[ { "cls_id": "homologset.agr.SGD:S000007272", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P00159-1", "uniprot_id": "CYB_RAT", "id": "P00159-1", "name": "Cytochrome b", "aln": "-MTNIRKSHPLFKIINHSFIDLPAPSNISSWWNFGSLLGVCLMVQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYT--FLETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAIVHLLFLHETGSNNPTGLNSDADKIPFHPYYTIKDLLGVFMLLLFLMTLVLFFPDLLGDPDNYTPAN----------------------------PLNTPPHIKPEWYFLFAYAILRS-------IPNKLGGVVALILS------------ILILAFLPFLHTSKQRSLTFRP--------------------------------------------------------------------ITQILYWILVANLLILTWIGGQPVEHPFIIIGQLASISYFSIILILMPISGIVEDKMLKWN---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00158-1", "uniprot_id": "CYB_MOUSE", "id": "P00158-1", "name": "Cytochrome b", "aln": "-MTNMRKTHPLFKIINHSFIDLPAPSNISSWWNFGSLLGVCLMVQIITGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYT--FMETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAIVHLLFLHETGSNNPTGLNSDADKIPFHPYYTIKDILGILIMFLILMTLVLFFPDMLGDPDNYMPAN----------------------------PLNTPPHIKPEWYFLFAYAILRS-------IPNKLGGVLALILS------------ILILALMPFLHTSKQRSLMFRP--------------------------------------------------------------------ITQILYWILVANLLILTWIGGQPVEHPFIIIGQLASISYFSIILILMPISGIIEDKMLKLYP--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00156-1", "uniprot_id": "CYB_HUMAN", "id": "P00156-1", "name": "Cytochrome b", "aln": "-MTPMRKTNPLMKLINHSFIDLPTPSNISAWWNFGSLLGACLILQITTGLFLAMHYSPDASTAFSSIAHITRDVNYGWIIRYLHANGASMFFICLFLHIGRGLYYGSFL--YSETWNIGIILLLATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGYSVDSPTLTRFFTFHFILPFIIAALATLHLLFLHETGSNNPLGITSHSDKITFHPYYTIKDALGLLLFLLSLMTLTLFSPDLLGDPDNYTLAN----------------------------PLNTPPHIKPEWYFLFAYTILRS-------VPNKLGGVLALLLS------------ILILAMIPILHMSKQQSMMFRP--------------------------------------------------------------------LSQSLYWLLAADLLILTWIGGQPVSYPFTIIGQVASVLYFTTILILMPTISLIENKMLKWA---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18935-1", "uniprot_id": "CYB_DROME", "id": "P18935-1", "name": "Cytochrome b", "aln": "MNKPLRNSHPLFKIANNALVDLPAPINISSWWNFGSLLGLCLIIQILTGLFLAMHYTADINLAFYSVNHICRDVNYGWLLRTLHANGASFFFICIYLHVGRGIYYGSYK--FTPTWLIGVIILFLVMGTAFMGYVLPWGQMSFWGATVITNLLSAIPYLGMDLVQWLWGGFAVDNATLTRFFTFHFILPFIVLAMTMIHLLFLHQTGSNNPIGLNSNIDKIPFHPYFTFKDIVGFIVMIFILISLVLISPNLLGDPDNFIPAN----------------------------PLVTPAHIQPEWYFLFAYAILRS-------IPNKLGGVIALVLS------------IAILMILPFYNLSKFRGIQFYP--------------------------------------------------------------------INQVMFWSMLVTVILLTWIGARPVEEPYVLIGQILTVVYFLYYLVN-PLITKWWDNLLN-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9ZZW7-1", "uniprot_id": "MBI3_YEAST", "id": "Q9ZZW7-1", "name": "Cytochrome b mRNA maturase bI3", "aln": "--MAFRKSNVYLSLVNSYIIDSPQPSSINYWWNMGSLLGLCLVIQIVTGIFMAMHYSSNIELAFSSVEHIMRDVHNGYILRYLHANGASFFFMVMFMHMAKGLYYGSYRSPRVTLWNVGVIIFILTIATAFLGYCCVYGQMSHWGATVITNLFSAIPFVGNDIVSWLWGGFNMEDPYYSNMMLNKSVLCWNIFIWMMNYYIIQLIIYNNMIWNKNNMVKMFIMRRKLAVINMYMYMKLIIQRTYSYYMNNTIIYDKNHKLNTDNPIYAYIGGLFEGDGWITISKKGKYLLYELGIEMHIRDIQLLYKIKNILGIGKVTIKKLKMKDGTIKEMCKFNVRNKNHLKNIIIPIFDKYPMLTNKHYDYLYFKDNLLKDIKYYNDLSYYLRPIKPFNTTEDILNKNYFSSWLIGFFEAESCFSIYKPMNKKMKTASFEVSQNNSMEVMLAIKSYLKITQNIYTDKFNNSRMTTKSINGIKNVVMFINNNPIKLLGYKKLQYLLFLKDLRTITKYNNYFKIPPKY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*::: :.: * ::* * * .*. ***:***** **::** **:*:****:.: ** *: ** ***: *:::* :******:**: :::*:.:*:****: * :*::::: .:.***:** :****.*********:****::* :*.*:***: ::.. :.:: : :* : : : :: .* . .. . : :: :. : : ::: : :: * :: :: * **: : ** : * * : : * *: *: .: : * . : : : : * .. . .: : . : * .:: ", "identical_positions": 95, "similar_positions": 117, "identity": "18.3%" }, { "cls_id": "homologset.agr.SGD:S000007273", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P00159-1", "uniprot_id": "CYB_RAT", "id": "P00159-1", "name": "Cytochrome b", "aln": "-MTNIRKSHPLFKIINHSFIDLPAPSNISSWWNFGSLLGVCLMVQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYTFLET--WNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAIVHLLFLHETGSNNPTGLNSDADKIPFHPYYTIKDLLGVFMLLLFLMTLVLFFPDLLGD----------------------------------------------------------------------------------PDNYTPANPLNTPPHIKP-------------------------------------------------------------EWYFLFAY---------------AILRSIPNKLG--------------------GVVALILSIL----------------ILAFLPFLHTSKQRS-----LTFRPITQILYWILVANLLILTWIGG-------QPVEHPFIIIG--------------------QLASISY-------------------------FSIILILMPISGIVEDKMLKWN------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00158-1", "uniprot_id": "CYB_MOUSE", "id": "P00158-1", "name": "Cytochrome b", "aln": "-MTNMRKTHPLFKIINHSFIDLPAPSNISSWWNFGSLLGVCLMVQIITGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYTFMET--WNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAIVHLLFLHETGSNNPTGLNSDADKIPFHPYYTIKDILGILIMFLILMTLVLFFPDMLGD----------------------------------------------------------------------------------PDNYMPANPLNTPPHIKP-------------------------------------------------------------EWYFLFAY---------------AILRSIPNKLG--------------------GVLALILSIL----------------ILALMPFLHTSKQRS-----LMFRPITQILYWILVANLLILTWIGG-------QPVEHPFIIIG--------------------QLASISY-------------------------FSIILILMPISGIIEDKMLKLYP-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00156-1", "uniprot_id": "CYB_HUMAN", "id": "P00156-1", "name": "Cytochrome b", "aln": "-MTPMRKTNPLMKLINHSFIDLPTPSNISAWWNFGSLLGACLILQITTGLFLAMHYSPDASTAFSSIAHITRDVNYGWIIRYLHANGASMFFICLFLHIGRGLYYGSFLYSET--WNIGIILLLATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGYSVDSPTLTRFFTFHFILPFIIAALATLHLLFLHETGSNNPLGITSHSDKITFHPYYTIKDALGLLLFLLSLMTLTLFSPDLLGD----------------------------------------------------------------------------------PDNYTLANPLNTPPHIKP-------------------------------------------------------------EWYFLFAY---------------TILRSVPNKLG--------------------GVLALLLSIL----------------ILAMIPILHMSKQQS-----MMFRPLSQSLYWLLAADLLILTWIGG-------QPVSYPFTIIG--------------------QVASVLY-------------------------FTTILILMPTISLIENKMLKWA------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18935-1", "uniprot_id": "CYB_DROME", "id": "P18935-1", "name": "Cytochrome b", "aln": "MNKPLRNSHPLFKIANNALVDLPAPINISSWWNFGSLLGLCLIIQILTGLFLAMHYTADINLAFYSVNHICRDVNYGWLLRTLHANGASFFFICIYLHVGRGIYYGSYKFTPT--WLIGVIILFLVMGTAFMGYVLPWGQMSFWGATVITNLLSAIPYLGMDLVQWLWGGFAVDNATLTRFFTFHFILPFIVLAMTMIHLLFLHQTGSNNPIGLNSNIDKIPFHPYFTFKDIVGFIVMIFILISLVLISPNLLGD----------------------------------------------------------------------------------PDNFIPANPLVTPAHIQP-------------------------------------------------------------EWYFLFAY---------------AILRSIPNKLG--------------------GVIALVLSIA----------------ILMILPFYNLSKFRG-----IQFYPINQVMFWSMLVTVILLTWIGA-------RPVEEPYVLIG--------------------QILTVVY-------------------------FLYYLVN-PLITKWWDNLLN--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P03879-1", "uniprot_id": "MBI4_YEAST", "id": "P03879-1", "name": "Intron-encoded RNA maturase bI4", "aln": "--MAFRKSNVYLSLVNSYIIDSPQPSSINYWWNMGSLLGLCLVIQIVTGIFMAMHYSSNIELAFSSVEHIMRDVHNGYILRYLHANGASFFFMVMFMHMAKGLYYGSYRSPRVTLWNVGVIIFILTIATAFLGYCCVYGQMSHWGATVITNLFSAIPFVGNDIVSWLWGGFSVSNPTIQRFFALHYLVPFIIAAMVIMHLMALHIHGSSNPLGITGNLDRIPMHSYFIFKDLVTVFLFMLILALFVFYSPNTLGQNMALLLITYVINILCAVCWKSLFIKYQWKIYNKTTYYFIIQNILNTKQLNNFVLKFNWTKQYNKMNIVSDLFNPNRVKYYYKEDNQQVTNMNSSNTHLTSNKKNLLVDTSETTRTTKNKFNYLLNIFNMKKMNQIITKRHYSIYKDSNIRFNQWLAGLIDGDGYFCITKNKYASCEITVELKDEKMLRQIQDKFGGSVKLRSGVKAIRYRLQNKEGMIKLINAVNGNIRNSKRLVQFNKVCILLNIDFKEPIKLTKDNAWFMGFFDADGTINYYYSGKLKIRPQLTISVTNKYLHDVEYYREVFGGNIYFDKAKNGYFKWSINNKELHNIFYTYNKSCPSKSNKGKRLFLIDKFYYLYDLLAFKAPHNTALYKAWLKFNEKWNNN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*::: :.: * ::* * * .*. ***:***** **::** **:*:****:.: ** *: ** ***: *:::* :******:**: :::*:.:*:****: . * :*::::: .:.***:** :****.*********:****::* :*.*:***::*...*: ***::*:::***: *:. :**: ** **.** *:... *:*.:*.*: :** : .::::: * :.: *: **: ** :* : .*: . : ** :: :**.: :*:* *:: *: :: ** : : . * : * : : : : . : : *. ::* :: .: * : . * . *: ", "identical_positions": 129, "similar_positions": 133, "identity": "20.16%" }, { "cls_id": "homologset.agr.SGD:S000007274", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q71S46-1", "uniprot_id": "AT5G3_RAT", "id": "Q71S46-1", "name": "ATP synthase F(0) complex subunit C3, mitochondrial", "aln": "MFACAKLACTPSLIR-----AGSRVAYRPISASVLSRPEASRTGEGSTVFNGAQNGVSQLIQREFQTSAISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48201-1", "uniprot_id": "AT5G3_HUMAN", "id": "P48201-1", "name": "ATP synthase F(0) complex subunit C3, mitochondrial", "aln": "MFACAKLACTPSLIR-----AGSRVAYRPISASVLSRPEASRTGEGSTVFNGAQNGVSQLIQREFQTSAISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56384-1", "uniprot_id": "AT5G3_MOUSE", "id": "P56384-1", "name": "ATP synthase F(0) complex subunit C3, mitochondrial", "aln": "MFACAKLARTPALIR-----AGSRVAYRPISASVLSRPE-TRTGEGSTVFNGAQNGVCQLIRREFQTSVISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9CR84-1", "uniprot_id": "AT5G1_MOUSE", "id": "Q9CR84-1", "name": "ATP synthase F(0) complex subunit C1, mitochondrial", "aln": "MQTTKALLISPALIR-----SCTRGLIRPVSASLLSRPEAPSKQPSCSSSP------LQVARREFQTSVISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06645-1", "uniprot_id": "AT5G1_RAT", "id": "Q06645-1", "name": "ATP synthase F(0) complex subunit C1, mitochondrial", "aln": "MQTTKALLISPVLIR-----SCTRGLIRPVSASLLSRPEAPSKKPSCCSSP------LQVARREFQTSVISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05496-1", "uniprot_id": "AT5G1_HUMAN", "id": "P05496-1", "name": "ATP synthase F(0) complex subunit C1, mitochondrial", "aln": "MQTAGALFISPALIR-----CCTRGLIRPVSASFLNSPVNSSKQPSYSNFP------LQVARREFQTSVVSRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56383-1", "uniprot_id": "AT5G2_MOUSE", "id": "P56383-1", "name": "ATP synthase F(0) complex subunit C2, mitochondrial", "aln": "MYACSKFVSTRSLIRSTSLRSTSQLLSRPLSAVELKRPQ-MPTDESLSSLAVRRPLTSLIPSRSFQTSAISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06646-1", "uniprot_id": "AT5G2_RAT", "id": "Q06646-1", "name": "ATP synthase F(0) complex subunit C2, mitochondrial", "aln": "MYACSKFVSTRSLIR-----STSQLLSRPLSAVELKRPQ-MPTDEGLSCLAVRRPLTSLIPSRSFQTSAISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q06055-1", "uniprot_id": "AT5G2_HUMAN", "id": "Q06055-1", "name": "ATP synthase F(0) complex subunit C2, mitochondrial", "aln": "MFACSKFVSTPSLVK-----STSQLLSRPLSAVVLKRPE-ILTDESLSSLAVSCPLTSLVSSRSFQTSAISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61829-1", "uniprot_id": "ATP9_YEAST", "id": "P61829-1", "name": "ATP synthase subunit 9, mitochondrial", "aln": "-----------------------------------------------------------------------MQLVLAAKYIGAGISTIGLLGAGIGIAIVFAALINGVSRNPSIKDTVFPMAILGFALSEATGLFCLMVSFLLLFGV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ***:**** :*:*: *:* **. **.:** * :****:*: :*. ********** *******:**:**.:", "identical_positions": 45, "similar_positions": 19, "identity": "30.61%" }, { "cls_id": "homologset.agr.SGD:S000007281", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P00406-1", "uniprot_id": "COX2_RAT", "id": "P00406-1", "name": "Cytochrome c oxidase subunit 2", "aln": "----------------MAYPFQLGLQDATSPIMEELTNFHDHTLMIVFLISSLVLYIISLMLTTKLTH----TSTMDAQEVETIWTILPAVILILIALPSLRILYMMDEINNPVLTVKTMGHQWYWSYEYTDYED-----LCFDSYMIPTNDLKPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATVTSNRPGLFYGQCSEICGSNHSFMPIVLEMVPLKYFENWSASMI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00405-1", "uniprot_id": "COX2_MOUSE", "id": "P00405-1", "name": "Cytochrome c oxidase subunit 2", "aln": "----------------MAYPFQLGLQDATSPIMEELMNFHDHTLMIVFLISSLVLYIISLMLTTKLTH----TSTMDAQEVETIWTILPAVILIMIALPSLRILYMMDEINNPVLTVKTMGHQWYWSYEYTDYED-----LCFDSYMIPTNDLKPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATVTSNRPGLFYGQCSEICGSNHSFMPIVLEMVPLKYFENWSASMI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00403-1", "uniprot_id": "COX2_HUMAN", "id": "P00403-1", "name": "Cytochrome c oxidase subunit 2", "aln": "----------------MAHAAQVGLQDATSPIMEELITFHDHALMIIFLICFLVLYALFLTLTTKLTN----TNISDAQEMETVWTILPAIILVLIALPSLRILYMTDEVNDPSLTIKSIGHQWYWTYEYTDYGG-----LIFNSYMLPPLFLEPGDLRLLDVDNRVVLPIEAPIRMMITSQDVLHSWAVPTLGLKTDAIPGRLNQTTFTATRPGVYYGQCSEICGANHSFMPIVLELIPLKIFEMGPVFTL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00408-1", "uniprot_id": "COX2_DROME", "id": "P00408-1", "name": "Cytochrome c oxidase subunit 2", "aln": "----------------MSTWANLGLQDSASPLMEQLIFFHDHALLILVMITVLVGYLMFMLFFNNYVN----RFLLHGQLIEMIWTILPAIILLFIALPSLRLLYLLDEINEPSVTLKSIGHQWYWSYEYSDFNN-----IEFDSYMIPTNELMTDGFRLLDVDNRVVLPMNSQIRILVTAADVIHSWTVPALGVKVDGTPGRLNQTNFFINRPGLFYGQCSEICGANHSFMPIVIESVPVNYFIKWISSNNS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00410-1", "uniprot_id": "COX2_YEAST", "id": "P00410-1", "name": "Cytochrome c oxidase subunit 2", "aln": "MLDLLRLQLTTFIMNDVPTPYACYFQDSATPNQEGILELHDNIMFYLLVILGLVSWMLYTIVMTYSKNPIAYKYIKHGQTIEVIWTIFPAVILLIIAFPSFILLYLCDEVISPAMTIKAIGYQWYWKYEYSDFINDSGETVEFESYVIPDELLEEGQLRLLDTDTSMVVPVDTHIRFVVTAADVIHDFAIPSLGIKVDATPGRLNQVSALIQREGVFYGACSELCGTGHANMPIKIEAVSLPKFLEWLNEQ--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :**:::* * : :**: :: :.:* ** : : . . : ..* :* :***:**:**::**:**: :**: **: .* :*:*::*:****.***:*: . : *:**::* * . :***:.*. :*:*:: **::::: **:*.:::*:**:*.*. ******.. * *::** ***:**:.*: *** :* :.: * ", "identical_positions": 80, "similar_positions": 81, "identity": "31.62%" }, { "cls_id": "homologset.agr.SGD:S000007283", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05505-1", "uniprot_id": "COX3_RAT", "id": "P05505-1", "name": "Cytochrome c oxidase subunit 3", "aln": "------MTHQTHAYHMVNPSPWPLTG--ALSALLLTSGLVMWFHYNSTILLSLGLLTNILTMYQWWRDIIREGTYQGHHTPIVQKGLRYGMILFIVSEVFFFAGFFWAFYHSSLVPTHDLGGCWPPTGITPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGNRNHMNQALLITILLGLYFTILQASEYFETSFSISDGIYGSTFFMATGFHGLHVIIGSTFLIVCLLRQLKFHFTSKHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00416-1", "uniprot_id": "COX3_MOUSE", "id": "P00416-1", "name": "Cytochrome c oxidase subunit 3", "aln": "------MTHQTHAYHMVNPSPWPLTG--AFSALLLTSGLVMWFHYNSITLLTLGLLTNILTMYQWWRDVIREGTYQGHHTPIVQKGLRYGMILFIVSEVFFFAGFFWAFYHSSLVPTHDLGGCWPPTGISPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGKRNHMNQALLITIMLGLYFTILQASEYFETSFSISDGIYGSTFFMATGFHGLHVIIGSTFLIVCLLRQLKFHFTSKHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00414-1", "uniprot_id": "COX3_HUMAN", "id": "P00414-1", "name": "Cytochrome c oxidase subunit 3", "aln": "------MTHQSHAYHMVKPSPWPLTG--ALSALLMTSGLAMWFHFHSMTLLMLGLLTNTLTMYQWWRDVTRESTYQGHHTPPVQKGLRYGMILFITSEVFFFAGFFWAFYHSSLAPTPQLGGHWPPTGITPLNPLEVPLLNTSVLLASGVSITWAHHSLMENNRNQMIQALLITILLGLYFTLLQASEYFESPFTISDGIYGSTFFVATGFHGLHVIIGSTFLTICFIRQLMFHFTSKHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9MIY4-1", "uniprot_id": "COX3_DANRE", "id": "Q9MIY4-1", "name": "Cytochrome c oxidase subunit 3", "aln": "------MAHQAHAYHMVDPSPWPLTG--AVAALLMSSGLAIWFHLHSMTLIVLGMILLILTMIQWWRDIIREGTFQGHHTPPVQKGLRYGMILFITSEVFFFLGFFWAFYHSSLAPTPELGGCWPPTGLTTLDPFEVPLLNTAVLLASGVTVTWAHHSLMEGERKQAIQSLALTILLGLYFTALQAMEYYEAPFTIADGVYGSTFFVATGFHGLHVIIGSTFLAVCLLRQVLFHFTSDHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P00417-1", "uniprot_id": "COX3_DROME", "id": "P00417-1", "name": "Cytochrome c oxidase subunit 3", "aln": "-----MSTHSNHPFHLVDYSPWPLTG--AIGAMTTVSGMVKWFHQYDISLFVLGNIITILTVYQWWRDVSREGTYQGLHTYAVTIGLRWGMILFILSEVLFFVSFFWAFFHSSLSPAIELGASWPPMGIISFNPFQIPLLNTAILLASGVTVTWAHHSLMENNHSQTTQGLFFTVLLGIYFTILQAYEYIEAPFTIADSIYGSTFFMATGFHGIHVLIGTTFLLVCLLRHLNNHFSKNHHFGFEAAAWYWHFVDVVWLFLYITIYWWGG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00420-1", "uniprot_id": "COX3_YEAST", "id": "P00420-1", "name": "Cytochrome c oxidase subunit 3", "aln": "MTHLERSRHQQHPFHMVMPSPWPIVVSFALLSLALSTALTMHGYIGNMNMVYLALFVLLTSSILWFRDIVAEATYLGDHTMAVRKGINLGFLMFVLSEVLIFAGLFWAYFHSAMSPDVTLGACWPPVGIEAVQPTELPLLNTIILLSSGATVTYSHHALIAGNRNKALSGLLITFWLIVIFVTCQYIEYTNAAFTISDGVYGSVFYAGTGLHFLHMVMLAAMLGVNYWRMRNYHLTAGHHVGYETTIIYTHVLDVIWLFLYVVFYWWGV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. *.:*:* ****:. *. :: :.:. : . :. *. : : *:**: *.*: * ** * *:. *:::*: ***::* .:***::**:: * **. *** *: ..:* ::***** :**:**.::*::**:*: .::.: ..* :*. * : *. * ** ::.*:*:*.:***.*: .**:* :*::: :::* : * *:: **.*:*:: * *.:**:*****: :**** ", "identical_positions": 90, "similar_positions": 95, "identity": "33.46%" }, { "cls_id": "homologset.agr.SGD:S000007348", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4FZG7-1", "uniprot_id": "TI8AB_MOUSE", "id": "Q4FZG7-1", "name": "Putative mitochondrial import inner membrane translocase subunit Tim8 A-B", "aln": "MESAWSSRGTSLGSSDP-QLQRFMEAEVQKQRVQLLIHHMTELCWEKCMDKPG-PRLDGRAELCLVNCVERFIDTSQFILNRLEQTQKARPLFSERLSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZV76-1", "uniprot_id": "D3ZV76_RAT", "id": "D3ZV76-1", "name": "Mitochondrial import inner membrane translocase subunit", "aln": "MESSWSSLGGSLGSADP-QLQRFMEAEVQKQRVQLLIHHMTELCWEKCMDKPG-PKLDSRAELCLVNCVERFIDTSQFILNRLEHTHKAKPFFSQNLSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVA2-1", "uniprot_id": "TIM8A_MOUSE", "id": "Q9WVA2-1", "name": "Mitochondrial import inner membrane translocase subunit Tim8 A", "aln": "MESSTSSSGSALGAVDP-QLQHFIEVETQKQRFQQLVHQMTELCWEKCMDKPG-PKLDSRAEACFVNCVERFIDTSQFILNRLEQTQKSKPVFSESLSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WVA1-1", "uniprot_id": "TIM8A_RAT", "id": "Q9WVA1-1", "name": "Mitochondrial import inner membrane translocase subunit Tim8 A", "aln": "MESSSSSSGSALAAVDP-QLQHFIEVETQKQRFQQLVHQMTELCWEKCMDKPG-PKLDSRAEACFVNCVERFIDTSQFILNRLEQTQKSKPVFSESLSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60220-1", "uniprot_id": "TIM8A_HUMAN", "id": "O60220-1", "name": "Mitochondrial import inner membrane translocase subunit Tim8 A", "aln": "MDSSSSSSAAGLGAVDP-QLQHFIEVETQKQRFQQLVHQMTELCWEKCMDKPG-PKLDSRAEACFVNCVERFIDTSQFILNRLEQTQKSKPVFSESLSD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DEM5-1", "uniprot_id": "TIM8A_DANRE", "id": "Q6DEM5-1", "name": "Mitochondrial import inner membrane translocase subunit Tim8 A", "aln": "MDTQG-------VATDP-QLQQFIEIESQKQRFQQLVHQMTEVCWEKCMDKPG-PKLDSRTEVCFVNCVERFIDTSQFILNRLEQTQRSRGAFSETMTD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P62077-1", "uniprot_id": "TIM8B_MOUSE", "id": "P62077-1", "name": "Mitochondrial import inner membrane translocase subunit Tim8 B", "aln": "MAELG-------EADEA-ELQRLVAAEQQKAQFTAQVHHFMELCWDKCVEKPG-SRLDSRTENCLSSCVDRFIDTTLAITGRFAQIVQK----GGQ---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62078-1", "uniprot_id": "TIM8B_RAT", "id": "P62078-1", "name": "Mitochondrial import inner membrane translocase subunit Tim8 B", "aln": "MAELG-------EADEA-ELQRLVAAEQQKAQFTAQVHHFMELCWDKCVEKPG-SRLDSRTENCLSSCVDRFIDTTLAITGRFAQIVQK----GGQ---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5J9-1", "uniprot_id": "TIM8B_HUMAN", "id": "Q9Y5J9-1", "name": "Mitochondrial import inner membrane translocase subunit Tim8 B", "aln": "MAELG-------EADEA-ELQRLVAAEQQKAQFTAQVHHFMELCWDKCVEKPG-NRLDSRTENCLSSCVDRFIDTTLAITSRFAQIVQK----GGQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y1A3-1", "uniprot_id": "TIM8_DROME", "id": "Q9Y1A3-1", "name": "Mitochondrial import inner membrane translocase subunit Tim8", "aln": "MSDFEN-----LSGNDK-ELQEFLLIEKQKAQVNAQIHEFNEICWEKCIGKPS-TKLDHATETCLSNCVDRFIDTSLLITQRFAQMLQKR--GGGDL--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P57744-1", "uniprot_id": "TIM8_YEAST", "id": "P57744-1", "name": "Mitochondrial import inner membrane translocase subunit TIM8", "aln": "MSSLSTSDLASLDDTSKKEIATFLEGENSKQKVQMSIHQFTNICFKKCVESVNDSNLSSQEEQCLSNCVNRFLDTNIRIVNGLQNTR------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . :: :: * .* :. :*.: ::*:.**: . . .*. * *: .**:**:**. * : : ", "identical_positions": 17, "similar_positions": 27, "identity": "17.17%" }, { "cls_id": "homologset.agr.SGD:S000007455", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NPE3-1", "uniprot_id": "NOP10_HUMAN", "id": "Q9NPE3-1", "name": "H/ACA ribonucleoprotein complex subunit 3", "aln": "MFLQYYLNEQGDRVYTLKKFDPMGQQTCSAHPARFSPDDKYSRHRITIKKRFKVLMTQQPRPVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CQS2-1", "uniprot_id": "NOP10_MOUSE", "id": "Q9CQS2-1", "name": "H/ACA ribonucleoprotein complex subunit 3", "aln": "MFLQYYLNEQGDRVYTLKKFDPMGQQTCSAHPARFSPDDKYSRHRITIKKRFKVLMTQQPRPVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZMP6-1", "uniprot_id": "D3ZMP6_RAT", "id": "D3ZMP6-1", "name": "H/ACA ribonucleoprotein complex subunit 3", "aln": "MFLQYYLNEQGDRVYTLKKFDPMGQQTCSAHPARFSPDDKYSRHRITIKKRFKVLMTQQPRPVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZWP8-1", "uniprot_id": "A0A8I5ZWP8_RAT", "id": "A0A8I5ZWP8-1", "name": "Nucleolar protein 10", "aln": "MFLQYYLNEQGDRVYTLKKFDPMGQQTCSAHSARFSTDDKYSKHRITIKKSFKVLMTQQPRAC-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DRH5-1", "uniprot_id": "NOP10_DANRE", "id": "Q6DRH5-1", "name": "H/ACA ribonucleoprotein complex subunit 3", "aln": "MFLQFYLNENGERVYTLKKVDPSGQPTSSAHPARFSPDDKFSRHRVTIKKRFGLLLTQQPRPVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6Q547-1", "uniprot_id": "NOP10_YEAST", "id": "Q6Q547-1", "name": "H/ACA ribonucleoprotein complex subunit NOP10", "aln": "MHLMYTLGPDGKRIYTLKKVTESGEITKSAHPARFSPDDKYSRQRVTLKKRFGLVPGQ------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9V5P6-1", "uniprot_id": "NOP10_DROME", "id": "Q9V5P6-1", "name": "H/ACA ribonucleoprotein complex subunit 3", "aln": "MYLMYTINENGDRVYTLKKRTEDGRPTLSAHPARFSPEDKYSRQRLTIKKRFGLLLTQKPEPIY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.* : :. :*.*:***** *. * ***.****.:**:*::*:*:** * :: * ", "identical_positions": 27, "similar_positions": 18, "identity": "42.19%" }, { "cls_id": "homologset.agr.SGD:S000007488", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K199-1", "uniprot_id": "COXM2_MOUSE", "id": "Q8K199-1", "name": "COX assembly mitochondrial protein 2 homolog", "aln": "MHPDLSPHLHTEECNVLINLLKECHKNHNILKFFGHCNDLDREMRKCLKNEYSERRT----RSREHGAAMRRRLSDPPEEAGR---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRP2-1", "uniprot_id": "COXM2_HUMAN", "id": "Q9NRP2-1", "name": "COX assembly mitochondrial protein 2 homolog", "aln": "MHPDLSPHLHTEECNVLINLLKECHKNHNILKFFGYCNDVDRELRKCLKNEYVENRT----KSREHGIAMRKKLFNPPEESEK---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DHJ6-1", "uniprot_id": "COXM2_DANRE", "id": "Q6DHJ6-1", "name": "COX assembly mitochondrial protein 2 homolog", "aln": "MHPDLSPHLHTDECNQLITLLKQCHKEHNVLKFFGTCNDMDRAMRECLRKEYQTKRE----RSKAHAEEMRRRLKEQPKEHP----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7Z0J4-1", "uniprot_id": "B7Z0J4_DROME", "id": "B7Z0J4-1", "name": "COX assembly mitochondrial protein", "aln": "MHTDLSSHLHTPACNKLIEELQACHENNAFAKFVGVCNSIDDKVVKCLKGERIARSA----ANRAKARERQAKYKEKLLQQESN--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3E7A4-1", "uniprot_id": "COXM2_YEAST", "id": "Q3E7A4-1", "name": "COX assembly mitochondrial protein 2", "aln": "MHPQLEAERF-HSCLDFINALDKCHQKEYYKRIFGLCNNEKDALNKCLKEASLNNKKRAVIESRIKRADVEKRWKKIEEEEYGEDAILKTILDRQYAKKKQESDNDANSK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.:*... . * :* *. **::. ::.* **. . : :**: . .: : . : . : ", "identical_positions": 13, "similar_positions": 27, "identity": "11.82%" }, { "cls_id": "homologset.agr.SGD:S000007496", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60841-1", "uniprot_id": "ENSA_RAT", "id": "P60841-1", "name": "Alpha-endosulfine", "aln": "MSQKQE--EENPAEETGEEK------QDTQEKEGILPEKAEEAKLKAKYPSLGQKPGG-SDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLPSAG-ADKNLVTGDHIPTPQDLPQRKSSLVT--SKLAGGQVE-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60840-1", "uniprot_id": "ENSA_MOUSE", "id": "P60840-1", "name": "Alpha-endosulfine", "aln": "MSQKQE--EENPAEETGEEK------QDTQEKEGILPEKAEEAKLKAKYPSLGQKPGG-SDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLPSAG-ADKNLVTGDHIPTPQDLPQRKSSLVT--SKLAGGQVE-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43768-1", "uniprot_id": "ENSA_HUMAN", "id": "O43768-1", "name": "Alpha-endosulfine", "aln": "MSQKQE--EENPAEETGEEK------QDTQEKEGILPERAEEAKLKAKYPSLGQKPGG-SDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLPSAG-PDKNLVTGDHIPTPQDLPQRKSSLVT--SKLAGGQVE-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56212-1", "uniprot_id": "ARP19_MOUSE", "id": "P56212-1", "name": "cAMP-regulated phosphoprotein 19", "aln": "MS------AEVPEAASAEEQ------KEMEDK-VTSPEKAEEAKLKARYPHLGQKPGG-SDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQLPAAA-PDKTEVTGDHIPTPQDLPQRKPSLVA--SKLAG---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q712U5-1", "uniprot_id": "ARP19_RAT", "id": "Q712U5-1", "name": "cAMP-regulated phosphoprotein 19", "aln": "MS------AEVPEAASAEEQ------KEMEDK-VTSPEKAEEAKLKARYPHLGQKPGG-SDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQLPAAA-PDKTEVTGDHIPTPQDLPQRKPSLVA--SKLAG---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56211-1", "uniprot_id": "ARP19_HUMAN", "id": "P56211-1", "name": "cAMP-regulated phosphoprotein 19", "aln": "MS------AEVPEAASAEEQ------KEMEDK-VTSPEKAEEAKLKARYPHLGQKPGG-SDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQLPTAA-PDKTEVTGDHIPTPQDLPQRKPSLVA--SKLAG---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BF67-1", "uniprot_id": "A2BF67_DANRE", "id": "A2BF67-1", "name": "Alpha-endosulfine", "aln": "MSSDNQ--DTETHPEQVDET------QESQDT-NSNPVRTEEAKLKAKYPNLGQKPGG-SDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLPAAAGPDKNIVTGDHIPTPQDLPQRKSSLVT--SKLAG---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q1L8X2-1", "uniprot_id": "ENSA_DANRE", "id": "Q1L8X2-1", "name": "Alpha-endosulfine", "aln": "MSENPDDLELESEEKQCELKSGCVYLQDSPEK-TCNPILSEEAKLKAKYPSLGHKPGG-SDFLMKRLQKGQKYFDSGDYNMAKAKMKSKHVVQSA-AEKSLVTGDHIPTPQDLPQRKNTILT--SKLAG---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUB8-1", "uniprot_id": "Q9VUB8_DROME", "id": "Q9VUB8-1", "name": "", "aln": "MSSAEE--NSNSPATTPQDT------ETTEQANLTDLEKIEEEKLKSKYPSGMRVPGGHSAFLQKRLQKGQKFFDSGDYQMAKQKGGGVKQVFAN----KVTTGEAIPTPETVPARKTSIIQPCNKFPATS-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9P305-1", "uniprot_id": "IGO2_YEAST", "id": "Q9P305-1", "name": "mRNA stability protein IGO2", "aln": "MS-----EDLSPTSSRVDLSN-----PHGFTKEGVDLSKLSPQELKL-YKMYGKLPSK-KDLLRHKMQD-RQYFDSGDYALKKAGVIKSDDVIVNNSSNNLPVTNPSGLRESIIRRRMSSSSGGDSISRQGSISSGPPPRSPNK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . : . :** * : *. . :* :::*. :::****** : * . . . : : : *: : ..:. ", "identical_positions": 16, "similar_positions": 28, "identity": "11.11%" }, { "cls_id": "homologset.agr.SGD:S000007547", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5TGZ0-1", "uniprot_id": "MIC10_HUMAN", "id": "Q5TGZ0-1", "name": "MICOS complex subunit MIC10", "aln": "------------------------MSESELGRKWDRCLADAVVKIGTGFGLGIVFSLTFFKRRMWPLAFGSGMGLGMAYSNCQHDFQ-----APYLLHGKYVKEQEQ----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TNS2-1", "uniprot_id": "MIC10_MOUSE", "id": "Q7TNS2-1", "name": "MICOS complex subunit Mic10", "aln": "------------------------MSESELGRKWDRCMADTVVKLGTGFGLGIVFSLTFFKRRMWPLAFGSGVGLGMAYSNCQHDFQ-----APYLLHGKYVKEQ------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2RYW8-1", "uniprot_id": "MIC10_RAT", "id": "B2RYW8-1", "name": "MICOS complex subunit Mic10", "aln": "------------------------MSESEPGRKWDRCMADALVKLGTGFGLGMVFSLTFFKRRKWPLAFGSGVGLGMAYSNCQHDFQ-----APYLLHGKYVKEQ------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZZC8-1", "uniprot_id": "A0A8I5ZZC8_RAT", "id": "A0A8I5ZZC8-1", "name": "MICOS complex subunit MIC10", "aln": "------------------------MLESELGRKWDGCMADAVLKLGSGFGLG-IFSLTFFKRRMWPLAFGSGVGLGMTYSNCQHDFLGSIFFSTWKICQRAVTYAENIPVGGKRNRVYFSGILKCPGVR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96VH5-1", "uniprot_id": "MIC10_YEAST", "id": "Q96VH5-1", "name": "MICOS complex subunit MIC10", "aln": "MSEQAQTQQPAKSTPSKDSNKNGSSVSTILDTKWDIVLSNMLVKTAMGFGVGVFTSVLFFKRRAFPVWLGIGFGVGRGYAEGDAIFR-----SSAGLRSSKV---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VY65-1", "uniprot_id": "Q9VY65_DROME", "id": "Q9VY65-1", "name": "MICOS complex subunit MIC10", "aln": "-----MSTTPED---RLRENIN-------------RCLSDSLVKGVGGLVIGSVVTLLFFRRRIWPVWLGTGFGVGVAYRGCEKELND------VKFGQRK----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W1B2-1", "uniprot_id": "Q9W1B2_DROME", "id": "Q9W1B2-1", "name": "MICOS complex subunit MIC10", "aln": "-----MSHEPQK---PAKSAVKEPPVVSEETRTTDKCLADFCLKGGSGLIIGSAVTLFFTRPQTYPIWLGLGVGMGVAYDCCQARWN-----------QQ-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: :* *: :* :: * : : :*: :* *.*:* * : ", "identical_positions": 10, "similar_positions": 16, "identity": "7.75%" }, { "cls_id": "homologset.agr.SGD:S000007586", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q06C60-1", "uniprot_id": "Q06C60_RAT", "id": "Q06C60-1", "name": "BolA-like protein 1", "aln": "-------MLSARLARCMVSMATRA-----CVSRGSAG---SAAGGPVEAAIRAKLEQALSPEVLELRNESGGHAVPAGSETHFRVAVVSSRFEGMSPLQRHRLVHEALSEELAGP----VHALAIQAKTPAQWRENPQLDISPPCLGGSKKTRGTS--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D8S9-1", "uniprot_id": "BOLA1_MOUSE", "id": "Q9D8S9-1", "name": "BolA-like protein 1", "aln": "-------MLSARSAQCMVSMATRS-----CVSRGSAG---SAAAGPVEAAIRAKLEQALSPEVLELRNESGGHAVPAGSETHFRVAVVSSRFEGMSPLQRHRLVHEALSEELAGP----VHALAIQAKTPAQWRENPQLDISPPCLGGSKKTRGTS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3E2-1", "uniprot_id": "BOLA1_HUMAN", "id": "Q9Y3E2-1", "name": "BolA-like protein 1", "aln": "-------MLSGRLVLGLVSMAGRV-----CLCQGSAG---SGAIGPVEAAIRTKLEEALSPEVLELRNESGGHAVPPGSETHFRVAVVSSRFEGLSPLQRHRLVHAALAEELGGP----VHALAIQARTPAQWRENSQLDTSPPCLGGNKKTLGTP--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N196-1", "uniprot_id": "A0A8M1N196_DANRE", "id": "A0A8M1N196-1", "name": "BolA-like protein 1", "aln": "-------MLSS-ALRCLRPISSTL-----VLSRPLAHHMDPSVPRPVETTIRTKLSKALNPEHLEVINESHMHAVPPGSESHFKVLVVSPQFEGLSLLQRHRLVNETLKEELSTC----IHALSIQAKTPQQWSSNPSLAKSPPCMGGSRHDHTMAEKLKAGRD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC53-1", "uniprot_id": "Q9VC53_DROME", "id": "Q9VC53-1", "name": "BolA-like protein DDB_G0274169", "aln": "MLNFTLRRLTGVSIRNLNQLTPTISSLGQILPRATMS-QEAGQYPPIESAMRKALNTELKPVYLEVINESPQHNVPKRSESHFRVFVVSEKFNDLTLIKRHRLVNDTVKNALKEAGFEFMHALSIEAKTPKQWEPEQEPEKSPPCLGGHGK-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3E793-1", "uniprot_id": "BOL1_YEAST", "id": "Q3E793-1", "name": "BolA-like protein 1", "aln": "--------MFKRAMSTDGPVARTI------LKRLECG-----------FPDYKNFAFGLYNDSHKHKGHAGVQGN-VSAETHFRIEMVSKKFEGLKLPQRHRMVYSLLQDEMAQANG--IHALQLSLKTPQEYESKAK--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: : : . : * : ..: : :*:**:: :** :*:.:. :***:* : : : :*** :. :** :: : . ", "identical_positions": 16, "similar_positions": 35, "identity": "9.76%" }, { "cls_id": "homologset.agr.SGD:S000007587", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96FX2-1", "uniprot_id": "DPH3_HUMAN", "id": "Q96FX2-1", "name": "Diphthamide biosynthesis protein 3", "aln": "MAVFHDEVEIEDFQYDEDSETYFYPCPCGDNFSITKEDLENGEDVATCPSCSLIIKVIYDKDQFVCGETVPAPSANKELVKC-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K0W9-1", "uniprot_id": "DPH3_MOUSE", "id": "Q8K0W9-1", "name": "Diphthamide biosynthesis protein 3", "aln": "MAVFHDEVEIEDFQYDEDSETYFYPCPCGDNFAITKEDLENGEDVATCPSCSLIIKVIYDKDQFMCGETVPAPSTNKELVKC-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4G8-1", "uniprot_id": "DPH3B_HUMAN", "id": "Q9H4G8-1", "name": "Putative DPH3 homolog B", "aln": "MAVFHDEVEIEDFQYDEDSETYFCPCPCGDNFSITKEELENGEGVAMCPGCSLIIKVIYDKDQFACGETVPVPSVNKE---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGQ9-1", "uniprot_id": "DPH3_DROME", "id": "Q9VGQ9-1", "name": "Diphthamide biosynthesis protein 3", "aln": "MSIYHDEVEIEDFEYDEEEEMYYYPCPCGDRFQISKEELIEGEEVATCPSCSLVIKVIYDPEMFKAEEDEES-ALNEKLGDLKLEKN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3E840-1", "uniprot_id": "DPH3_YEAST", "id": "Q3E840-1", "name": "Diphthamide biosynthesis protein 3", "aln": "MSTY-DEIEIEDMTFEPENQMFTYPCPCGDRFQIYLDDMFEGEKVAVCPSCSLMIDVVFDKEDLAEYYEEAGIHPPEPIAAAA----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : **:****: :: :.: : ******.* * ::: :** ** **.***:*.*::* : : : ", "identical_positions": 27, "similar_positions": 23, "identity": "31.03%" }, { "cls_id": "homologset.agr.SGD:S000007588", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88892-1", "uniprot_id": "SERF1_MOUSE", "id": "O88892-1", "name": "Small EDRK-rich factor 1", "aln": "--------------------------------------------------------------------------------------------------MARGNQREIARQKNMKKTQEISKGKRKEDSLTASQRKQRDSEIMQQKQKIANEKKSMQT-TEK-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A096MK48-1", "uniprot_id": "A0A096MK48_RAT", "id": "A0A096MK48-1", "name": "", "aln": "QRTLFLASAHSSPGGRAVGRGRSEASGPGTRTRSGSPATPRLLWVGGRGGRLTERGVATPRALSGLSLPQRRAATAAERASRRCFSRSLSSSLRLVVSMARGNQREIARQKNMKKTQEISKGKRKEDSLTASQRKQRDSEIMQQKQKVANEKKSMQT-RDK-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75920-1", "uniprot_id": "SERF1_HUMAN", "id": "O75920-1", "name": "Small EDRK-rich factor 1", "aln": "--------------------------------------------------------------------------------------------------MARGNQRELARQKNMKKTQEISKGKRKEDSLTASQRKQSSGGQKSESKMSAGPHLPLKAPRENPCFPLPAAGGSRYYLAYGSITPISAFVFVVFFSVFFPSFYEDFCCWI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P84102-1", "uniprot_id": "SERF2_MOUSE", "id": "P84102-1", "name": "Small EDRK-rich factor 2", "aln": "--------------------------------------------------------------------------------------------------MTRGNQRELARQKNMKKQSDSVKGKRRDDGLSAAARKQRDSEIMQQKQKKANEKKEEPK---------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P84101-1", "uniprot_id": "SERF2_HUMAN", "id": "P84101-1", "name": "Small EDRK-rich factor 2", "aln": "--------------------------------------------------------------------------------------------------MTRGNQRELARQKNMKKQSDSVKGKRRDDGLSAAARKQRDSEIMQQKQKKANEKKEEPK---------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q4L4-1", "uniprot_id": "F1Q4L4_DANRE", "id": "F1Q4L4-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------MTRGNQRELARQKNAKKQTDSSKGKRNEDGLSAAARKQRDAEIMQQKQKKANEK-PEPKGK-------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEW2-1", "uniprot_id": "SERFL_DROME", "id": "Q9VEW2-1", "name": "Putative SERF-like protein", "aln": "--------------------------------------------------------------------------------------------------MTRGNQRDLARQKNQKKQADLTKGKR-TDNLTVEQRKARDAELMREKQKKKEEAAAAGTSK-------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3E7B7-1", "uniprot_id": "YD85C_YEAST", "id": "Q3E7B7-1", "name": "SERF-like protein YDL085C-A", "aln": "--------------------------------------------------------------------------------------------------MARGNQRDLARQKNLKKQKDMAKNQKKSGDP--KKRMESDAEILRQKQAAADARREAEKLEKLKAEKTRR----------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*****::***** ** : *.:: .. * .. :.: ", "identical_positions": 15, "similar_positions": 14, "identity": "7.21%" }, { "cls_id": "homologset.agr.SGD:S000007596", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIP1-1", "uniprot_id": "PELO_RAT", "id": "Q5XIP1-1", "name": "Protein pelota homolog", "aln": "MKLVRKDIEKDNAGQVTLVPEEPEDMWHTYNLVQVGDSLRASTIRKVQTESSTGSVGSNRVRTTLTLCVEAIDFDSQACQLRVKGTNIQENEYVKMGAYHTIELEPNRQFTLAKKQWDSVVLERIEQACDPAWSADVAAVVMQEGLAHVCLVTPSMTLTRAKVEVNIPRKRKGNCSQHDRALERFYEQVVQAIQRHINFEVVKCILVASPGFVREQFCDYMFQQAVKTDNKVLLENRSKFLQVHASSGHKYSLKEVLCDPTVASRLSDTKAAGEVKALDDFYKMLQHEPDRAFYGLKQVERANEALAIDTLLISDELFRHQDVATRSRYVRLVDSVKENAGTVRIFSSLHVSGEQLGQLTGVAAILRFPVPELSDQEDD----------SSSEED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80X73-1", "uniprot_id": "PELO_MOUSE", "id": "Q80X73-1", "name": "Protein pelota homolog", "aln": "MKLVRKDIEKDNAGQVTLVPEEPEDMWHTFNLVQVGDSLRASTIRKVQTESSTGSVGSNRVRTTLTLCVEAIDFDSQACQLRVKGTNIQENEYVKMGAYHTIELEPNRQFTLAKKQWDSVVLERIEQACDPAWSADVAAVVMQEGLAHVCLVTPSMTLTRAKVEVNIPRKRKGNCSQHDRALERFYEQVVQAIQRHINFEVVKCVLVASPGFVREQFCDYMFQQAVKTDNKVLLENRSKFLQVHASSGHKYSLKEALCDPTVASRLSDTKAAGEVKALDDFYKMLQHEPDRAFYGLKQVERANEALAIDTLLISDELFRHQDVATRSRYVRLVDSVKENAGTVRIFSSLHVSGEQLGQLTGVAAILRFPVPELSDQEDD----------SSSEED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BRX2-1", "uniprot_id": "PELO_HUMAN", "id": "Q9BRX2-1", "name": "Protein pelota homolog", "aln": "MKLVRKNIEKDNAGQVTLVPEEPEDMWHTYNLVQVGDSLRASTIRKVQTESSTGSVGSNRVRTTLTLCVEAIDFDSQACQLRVKGTNIQENEYVKMGAYHTIELEPNRQFTLAKKQWDSVVLERIEQACDPAWSADVAAVVMQEGLAHICLVTPSMTLTRAKVEVNIPRKRKGNCSQHDRALERFYEQVVQAIQRHIHFDVVKCILVASPGFVREQFCDYLFQQAVKTDNKLLLENRSKFLQVHASSGHKYSLKEALCDPTVASRLSDTKAAGEVKALDDFYKMLQHEPDRAFYGLKQVEKANEAMAIDTLLISDELFRHQDVATRSRYVRLVDSVKENAGTVRIFSSLHVSGEQLSQLTGVAAILRFPVPELSDQEGD----------SSSEED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZWC4-1", "uniprot_id": "PELO_DANRE", "id": "Q7ZWC4-1", "name": "Protein pelota homolog", "aln": "MKLVHKDIEKDNAGQVTLIPDEAEDMWHTYNLLQVGDSLRASTIRKVQTESSTGSVGSSRVRTTLTLCVETIDFDSQACQLRVKGTNIQENQYVKMGAYHTIELELNRKFTLAKKVWDSVVLDRIEQACDPAQKADVAAVVMQEGLANLVLVTPAMTLLRAKVEVTIPRKRKGSCTQHDKALERFYEAVMQGILRHFNFDVVKCILVASPGFVKDQFISYLFKEAVRQDCKLLLENRSKFMVVHSSSGHKYSLKEVLCDPAVTARLSDTKAAGEVKALEDFYKMLQQEPDRAFYGLAHVERASEALAIDILLISDTLFRHQDVATRGRYVRLVDNVKENGGTVRIFSSLHVSGEQLNQLSGVAAILRFPIADVSEPEEN----------SSSDED", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48612-1", "uniprot_id": "PELO_DROME", "id": "P48612-1", "name": "Protein pelota", "aln": "MKLLGKYVDKGMQGNVTLVPEESEDMWHAYNLIAKGDSVRSTTIRKVQNETATGSSTSSRVRTTLTIAVESIDFDTQACVLRLKGRNIEENQYVKMGAYHTLDLELNRKFELRKPEWDTIALERIEMACDPTQSADVAAVVMQEGLAHVCLITASMTLVRSKIEVSIPRKRKGSVQQHEKGLAKFYEQVMQSILRHVNFDVVKCVLIASPGFVRDQFYDYMFQQAVKMDYKLLLDNKSKFMLVHASSGFKHSLREILQDPAVLAKMSDTKAAGEVKALEQFYMMLQCEPAKAFYGKKHVLQAAESQAIETLLISDNLFRCQDVSLRKEYVNLVESIRDAGGEVKIFSSMHISGEQLAQLTGIAALLRFPMPELEDSDDDDDEDGAAGGVADSDSD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q96VH2-1", "uniprot_id": "YC01B_YEAST", "id": "Q96VH2-1", "name": "Putative pelota-like protein YCL001W-B", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDDFLEHLSKDDNKAWYGAEETERAAKLDAIETLLITDSVLKRNDVKKREKYLDLIENSGNNNGKIFVLSTSKIT---VSNLTNQQI-------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::* *. : :*:** .. :* : **: ***:* ::: :** * .*: *::. : * : ::*: ::: : :*:. ", "identical_positions": 20, "similar_positions": 34, "identity": "5.06%" }, { "cls_id": "homologset.agr.SGD:S000007603", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZEI7-1", "uniprot_id": "D3ZEI7_RAT", "id": "D3ZEI7-1", "name": "General transcription and DNA repair factor IIH subunit TFB5", "aln": "MVNVLKGVLIECDPAMKQFLLYLDESNALGKKFIIQDIDDTHVFVIAELVNVLQERVGELMDQNAF-SLTQK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZYL4-1", "uniprot_id": "TF2H5_HUMAN", "id": "Q6ZYL4-1", "name": "General transcription factor IIH subunit 5", "aln": "MVNVLKGVLIECDPAMKQFLLYLDESNALGKKFIIQDIDDTHVFVIAELVNVLQERVGELMDQNAF-SLTQK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K2X8-1", "uniprot_id": "TF2H5_MOUSE", "id": "Q8K2X8-1", "name": "General transcription factor IIH subunit 5", "aln": "MVNVLKGVLIECDPAMKQFLLYLDEANALGKKFIIQDIDDTHVFVIAELVNVLQERVGELMDQNAF-SLTQK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K606-1", "uniprot_id": "A0A0G2K606_RAT", "id": "A0A0G2K606-1", "name": "General transcription and DNA repair factor IIH subunit TFB5", "aln": "MANTLKGVLIECDSATKQFFLYLNESNALGKKFVIQDIDDTHAFVIVELVNVLQEQVGELMDQNAS-CLTQK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SNQ6-1", "uniprot_id": "Q5SNQ6_DANRE", "id": "Q5SNQ6-1", "name": "General transcription and DNA repair factor IIH subunit TFB5", "aln": "MVNVLKGVLVECDPAMKQFLLYLDETSALGKKFIIQDLDDTHVFILAEVVQILQERVGELMDQNSF-PITQK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7Z018-1", "uniprot_id": "B7Z018_DROME", "id": "B7Z018-1", "name": "General transcription and DNA repair factor IIH subunit TFB5", "aln": "MVNVMKGVLVECDPAMKQFLLHLDEKLALGRKFIIQDLDENHLFISTDIVEVLQARVDDLMDRISF-PLHDKDA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3E7C1-1", "uniprot_id": "TFB5_YEAST", "id": "Q3E7C1-1", "name": "General transcription and DNA repair factor IIH subunit TFB5", "aln": "MARARKGALVQCDPSIKALILQIDAKMS---DIVLEELDDTHLLVNPSKVEFVKHELNRLLSKNIYNPMDEEENQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*... **.*::**.: * ::* :: : .::::::*:.* :: . *:.:: .:. *:.: : :: ", "identical_positions": 12, "similar_positions": 38, "identity": "16.0%" }, { "cls_id": "homologset.agr.SGD:S000007605", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0K036-1", "uniprot_id": "SDHF1_RAT", "id": "B0K036-1", "name": "Succinate dehydrogenase assembly factor 1, mitochondrial", "aln": "-MSRLSRLQRQVLSLYRELLRAGRGKPGAEAR-----VRAEFRQHASLPRSDVLRIEYLYRRGRRQLQLLRSGHATAMGTFVRPRGPTEEPVDATAPGNRLDDSDALKNPCEGTGARETRSDGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U276-1", "uniprot_id": "SDHF1_MOUSE", "id": "Q3U276-1", "name": "Succinate dehydrogenase assembly factor 1, mitochondrial", "aln": "-MSRPSRLQRQVLSLYRELLRAGRGTPGAEAR-----VRAEFRQHASLPRTDVLRIEYLYRRGRRQLQLLRSGHATAMGTFVRPRGPAEEPGDATAPGTRLDDGGAPKNSCEDTGARETRSDGR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NFY7-1", "uniprot_id": "SDHF1_HUMAN", "id": "A6NFY7-1", "name": "Succinate dehydrogenase assembly factor 1, mitochondrial", "aln": "-MSRHSRLQRQVLSLYRDLLRAGRGKPGAEAR-----VRAEFRQHAGLPRSDVLRIEYLYRRGRRQLQLLRSGHATAMGAFVRPRAPTGEPG---GVGCQPDDGDSPRNPHDSTGAPETRPDGR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3E785-1", "uniprot_id": "SDHF1_YEAST", "id": "Q3E785-1", "name": "Succinate dehydrogenase assembly factor 1, mitochondrial", "aln": "MPKRLSGLQKEVLHLYRASIRTAHTKPKENQVNFVNYIHEEFGKYRNLPRKDFTTIEHLLRVGNKKIATFSHPELTNIH---------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* * **::** *** :*:.: .* : :: ** :: .***.*. **:* * *.::: : . * : ", "identical_positions": 23, "similar_positions": 24, "identity": "18.55%" }, { "cls_id": "homologset.agr.SGD:S000007620", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q05310-1", "uniprot_id": "L10K_RAT", "id": "Q05310-1", "name": "Leydig cell tumor 10 kDa protein", "aln": "MAQGQRKFQAQKP-KSK--AAAAERSRGPRKGGRV-IGPKKARVVQQQKLKKSLEVGIRKKIEHDVVMKASSSLPKKLALLKGASKK---TGAT-PGKTPS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1F0-1", "uniprot_id": "L10K_MOUSE", "id": "Q8R1F0-1", "name": "Leydig cell tumor 10 kDa protein homolog", "aln": "MAQGQRKFQAQKP-KSK--AAAAERSRGPRKGGRV-IAPKKARVVQQQKLKKSLEVGIRKKIEHDVVMKASSSLPKRLALLKGASKK---SEATIPGKTPS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UNZ5-1", "uniprot_id": "L10K_HUMAN", "id": "Q9UNZ5-1", "name": "Leydig cell tumor 10 kDa protein homolog", "aln": "MAQGQRKFQAHKPAKSKTAAAASEKNRGPRKGGRV-IAPKKARVVQQQKLKKNLEVGIRKKIEHDVVMKASSSLPKKLALLKAPAKKK-GAAAATSSKTPS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24JV4-1", "uniprot_id": "U390_DANRE", "id": "Q24JV4-1", "name": "UPF0390 protein zgc136864", "aln": "MAQGKQKFKAQRPGGAK---KHQNKPKGLKKGGRI-IAPKKAQVVQQQKLKKGLEVAIRNKIEHEVTQKASTSLHKKLSVLKTPAQKSGTAGAPKPAAGPSK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3E747-1", "uniprot_id": "YL363_YEAST", "id": "Q3E747-1", "name": "Uncharacterized protein YLR363W-A", "aln": "MPQKPLKVTKKAK-DPR---RVTKKQKNLRKAAPLQLKSKKKSLQHLKKLKK--SSSLTETTERLVASKVG-----HLELLRGTRKEL--EKGKKNSK----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.* *. : .: :: :. :*.. : : .** : : :**** . .: :. *: *. *.. :* :*: . :: . . ", "identical_positions": 15, "similar_positions": 35, "identity": "14.71%" }, { "cls_id": "homologset.agr.SGD:S000007626", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N2Z9-1", "uniprot_id": "CENPS_HUMAN", "id": "Q8N2Z9-1", "name": "Centromere protein S", "aln": "MEEEAETEEQQRFSYQQRLKAAVHYTVGCLCEEVALDKEMQFSKQTIAAISELTFRQCENFAKDLEMFARHAKRTTINTEDVKLLARRSNSLLKYITDKSEEIAQINLERKAQKKKKSEDGSKNSRQ-----PAEAGVVESEN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D084-1", "uniprot_id": "CENPS_MOUSE", "id": "Q9D084-1", "name": "Centromere protein S", "aln": "-MEEVEAEEPQEFSHRQRLKAAVHYTVGCLCQEVTLNKQVNFSKQTIAAISEVTFRQCENFAKDLEMFARHAKRSTVTTEDVKLLARRNNSLLKYITEKNEEIAQLNLKGKAKKKRKPEDESRSSRESMAEELDGAEELQSES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3E835-1", "uniprot_id": "CENPS_YEAST", "id": "Q3E835-1", "name": "Inner kinetochore subunit MHF1", "aln": "----MNDDED-----RAQLKARLWIRVEERLQQVLSSEDIKYTPRFINSLLELAYLQLGEMGSDLQAFARHAGRGVVNKSDLMLYLRKQPDLQERVTQE--------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* : :*** : * ::* .:::::: : * :: *::: * ::..**: ***** * .:...*: * *:. .* : :*:: ", "identical_positions": 22, "similar_positions": 38, "identity": "15.38%" }, { "cls_id": "homologset.agr.SGD:S000007651", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y5U9-1", "uniprot_id": "IR3IP_HUMAN", "id": "Q9Y5U9-1", "name": "Immediate early response 3-interacting protein 1", "aln": "-------MAFTLYSLL-QAALLCVNAIAVLHE-ERFLKNIGWGTD-----------QGIG-GFG--EEPGIKSQL--------MNLIRSVRTVMRVPLIIVNSIAIV----LLLLFG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CR20-1", "uniprot_id": "IR3IP_MOUSE", "id": "Q9CR20-1", "name": "Immediate early response 3-interacting protein 1", "aln": "-------MAFTLYSLM-QAALLCVNAIAVLHE-ERFLKNIGWGTD-----------QGIG-GFG--EEPGIKSQL--------MNLIRSVRTVMRVPLIIVNSITIV----LLLLFG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4VBI2-1", "uniprot_id": "IR3IP_DANRE", "id": "Q4VBI2-1", "name": "Immediate early response 3-interacting protein 1", "aln": "-------MAFTLYALI-QTAILFTNAIAVLHE-ERFLSKIGWGAE-----------QGVG-GFG--DDPGIKAQL--------LNLIRSVRTVMRVPLIAVNSVCIV----LLLLFG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3E834-1", "uniprot_id": "YOS1_YEAST", "id": "Q3E834-1", "name": "Protein transport protein YOS1", "aln": "------MVLFGLGRLF-YVILLLINAVAVLSE-ERFLRRIGLGRS-----------NDETPVFGQ-DQNTTKSKV--------VQLIGAVQTLLRIPLIGINILVIV----YELLLG", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VTE1-1", "uniprot_id": "Q9VTE1_DROME", "id": "Q9VTE1-1", "name": "Immediate early response 3-interacting protein 1", "aln": "--------MFTLWTLI-ESSLLCLNAVCILHE-ERFLAKFGWGRQ-----------AGQQ-DFG---APTAKDQV--------LNLIRSIRTVAKIPLIFLNIIAII----FKLLLG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7TNZ8-1", "uniprot_id": "Q7TNZ8_RAT", "id": "Q7TNZ8-1", "name": "", "aln": "MQVRAASGHQGLCSCVPDAQLIVAEQVQCVCKGLTFMSVLPFEEEVKCLVKKYQEVAGCG-QWQCHILVGIREKVSGAWGQFEVTIAFTLYSLMQAALLCVNTTSVLHEECFLKNIG", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . :: : : : : *: : . . : : :: : : :: :: : .*: :* :: :*", "identical_positions": 5, "similar_positions": 28, "identity": "4.27%" }, { "cls_id": "homologset.agr.SGD:S000028508", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5EB76-1", "uniprot_id": "VA0E2_RAT", "id": "Q5EB76-1", "name": "V-type proton ATPase subunit e 2", "aln": "MTAHSFALPVIIFTTFWGLIGIAGPWFVPKGPNRGVIITMLVATAVCCYLFWLIAILAQLNPLFGPQLKNETIWYVRFLWE-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XE7-1", "uniprot_id": "VA0E2_MOUSE", "id": "Q91XE7-1", "name": "V-type proton ATPase subunit e 2", "aln": "MTAHSFALPVIIFTTFWGLIGIAGPWFVPKGPNRGVIITMLVATAVCCYLFWLIAILAQLNPLFGPQLKNETIWYVRFLWE-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NHE4-1", "uniprot_id": "VA0E2_HUMAN", "id": "Q8NHE4-1", "name": "V-type proton ATPase subunit e 2", "aln": "MTAHSFALPVIIFTTFWGLVGIAGPWFVPKGPNRGVIITMLVATAVCCYLFWLIAILAQLNPLFGPQLKNETIWYVRFLWE-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CQD8-1", "uniprot_id": "VA0E1_MOUSE", "id": "Q9CQD8-1", "name": "V-type proton ATPase subunit e 1", "aln": "MAYHGLTVPLIVMSVFWGFVGLLVPWFIPKGPNRGVIITMLVTCSVCCYLFWLIAILAQLNPLFGPQLKNETIWYLKYHWP-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q794C0-1", "uniprot_id": "VA0E1_RAT", "id": "Q794C0-1", "name": "V-type proton ATPase subunit e 1", "aln": "MAYHGLTVPLIVMSVFWGFVGLLVPWFIPKGPNRGVIITMLVTCSVCCYLFWLIAILAQLNPLFGPQLKNETIWYLKYHWP-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15342-1", "uniprot_id": "VA0E1_HUMAN", "id": "O15342-1", "name": "V-type proton ATPase subunit e 1", "aln": "MAYHGLTVPLIVMSVFWGFVGFLVPWFIPKGPNRGVIITMLVTCSVCCYLFWLIAILAQLNPLFGPQLKNETIWYLKYHWP-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZG7-1", "uniprot_id": "Q9VZG7_DROME", "id": "Q9VZG7-1", "name": "V-type proton ATPase subunit", "aln": "--M-EVFLTIVFFTIFWAAVAKYGPILFTKQPHDDLVRCIFLLTAVVCWLFWLCCYLAQLNPLLGPKLNGNTIRIIASSWGNPIKEG-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZE9-1", "uniprot_id": "Q9VZE9_DROME", "id": "Q9VZE9-1", "name": "V-type proton ATPase subunit", "aln": "--MGAAFFPVLFFTALWGGVGIAMPIMTPKGPHQNLIRCILMLTAACCWLFWLCCYMAQMNPLIGPKLKRDVVAMIGRSWNNPIVAG-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VP18-1", "uniprot_id": "Q9VP18_DROME", "id": "Q9VP18-1", "name": "V-type proton ATPase subunit", "aln": "--MVSEWVAPIVITSIWAFIGIICP-FFARGPNRGVTQCCLMLTAATCWLFWLCCYMTQLNPLIGPKLSMNEIMIMAREWGNEIKDTMAVTV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VEQ6-1", "uniprot_id": "Q9VEQ6_DROME", "id": "Q9VEQ6-1", "name": "V-type proton ATPase subunit", "aln": "---MDKHVAFMVITVFWLLFAIIGFLVSYRYEERGLIRCCVILTAVCCYLAWMVTFVMQLNPLTGPRAKQKIILGMITYWPRSIIHDEKDP-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3E7B6-1", "uniprot_id": "VA0E_YEAST", "id": "Q3E7B6-1", "name": "V-type proton ATPase subunit e", "aln": "---MSSFYTVVGVFIVVSAMSVLFWIMAPKN-NQAVWRSTVILTLAMMFLMWAITFLCQLHPLVAPRRSD-----LRPEFAE----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . .. . : . : .: . :* * : *::** .*: . : : ", "identical_positions": 6, "similar_positions": 22, "identity": "6.52%" }, { "cls_id": "homologset.agr.SGD:S000028509", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A5T1-1", "uniprot_id": "D4A5T1_RAT", "id": "D4A5T1-1", "name": "Splicing factor 3B subunit 5", "aln": "MTDRYTIHSQLEHLQSKYIGTGHADTTKWEWLVNQHRDSYCSYMGHFDLLNYFAIAENESKAR-VRFNLMEKMLQPSGPPADKPEEN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q923D4-1", "uniprot_id": "SF3B5_MOUSE", "id": "Q923D4-1", "name": "Splicing factor 3B subunit 5", "aln": "MTDRYTIHSQLEHLQSKYIGTGHADTTKWEWLVNQHRDSYCSYMGHFDLLNYFAIAENESKAR-VRFNLMEKMLQPSGPPADKPEEN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BWJ5-1", "uniprot_id": "SF3B5_HUMAN", "id": "Q9BWJ5-1", "name": "Splicing factor 3B subunit 5", "aln": "MTDRYTIHSQLEHLQSKYIGTGHADTTKWEWLVNQHRDSYCSYMGHFDLLNYFAIAENESKAR-VRFNLMEKMLQPCGPPADKPEEN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHI4-1", "uniprot_id": "SF3B5_DROME", "id": "Q9VHI4-1", "name": "Splicing factor 3B subunit 5", "aln": "MGERYNIHSQLEHLQSKYIGTGHADTTKFEWLTNQHRDSLASYMGHYDILNYFAIAENESKAR-VRFNLMERMLQPCGPPPEKLED-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0C074-1", "uniprot_id": "YSF3_YEAST", "id": "P0C074-1", "name": "RDS3 complex subunit 10", "aln": "MAEKQRQLKLQKIYKQKYIGLGDESTTREQWQRNVRNDTLNTLQGHSASLEYVSLSRGDLSIRDTRIHLLKSMS-P-GYKAYLREER", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: . : :.**** *. .**: :* * :.*: : ** *:*.:::..: . * .*::*:: * * * . *: ", "identical_positions": 22, "similar_positions": 30, "identity": "25.29%" }, { "cls_id": "homologset.agr.SGD:S000028510", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VYX1-1", "uniprot_id": "ENY2_DROME", "id": "Q9VYX1-1", "name": "Enhancer of yellow 2 transcription factor", "aln": "-----MSTSGAVD-----QYTVLTGDRSKIKDLLCSRLTECGWRDEVRLMCRNILMEKGTNNSFTVEQLIAEVTPKARTLVPDAVKKELLMKIRTILTEIEEEPDEPEDES", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VI60-1", "uniprot_id": "ENY2B_DROME", "id": "Q9VI60-1", "name": "Enhancer of yellow 2b transcription factor", "aln": "---MTINKETGTDPDPGYKPTLRSQDKAALKELLHTRLVECGWHKDIKEMIRNIIMERGVDN-INRDQLAAQIVPQARALVPEVVKNEMMLRVHAALDK------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9NPA8-1", "uniprot_id": "ENY2_HUMAN", "id": "Q9NPA8-1", "name": "Transcription and mRNA export factor ENY2", "aln": "MVVSKMNKDAQMRAAIN-QKLIETGERERLKELLRAKLIECGWKDQLKAHCKEVIKEKGLEH-VTVDDLVAEITPKGRALVPDSVKKELLQRIRTFLAQHASL--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JIX0-1", "uniprot_id": "ENY2_MOUSE", "id": "Q9JIX0-1", "name": "Transcription and mRNA export factor ENY2", "aln": "MVVSKMNKDAQMRAAIN-QKLIETGERERLKELLRAKLIECGWKDQLKAHCKEVIKEKGLEH-VTVDDLVAEITPKGRALVPDSVKKELLQRIRTFLAQHASL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZWF5-1", "uniprot_id": "D3ZWF5_RAT", "id": "D3ZWF5-1", "name": "Transcription and mRNA export factor ENY2", "aln": "-MVSKMNKDAQMRAAIN-QKLIETGERERLKELLRAKLIECGWKDQLKAHCKEVIKEKGLEH-VTVDDLVAEITPKGRALVPDSVKKELLQRIRTFLAQHASL--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DH42-1", "uniprot_id": "ENY2_DANRE", "id": "Q6DH42-1", "name": "Transcription and mRNA export factor ENY2", "aln": "-----MSKESQMRAAIN-QKLIEMGERERLKELLRAKLIECGWRDQLKALCKEVIKEKGIEN-VTVEDLVAGVTPKGRALVPDSVKKELLQRIRAFLAQHST---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6WNK7-1", "uniprot_id": "SUS1_YEAST", "id": "Q6WNK7-1", "name": "SAGA complex subunit SUS1", "aln": "-----MTMDTAQLKSQIQQYLVESGNYELISNELKARLLQEGWVDKVKDLTKSEMNINESTN---FTQILSTVEPKALEMVSDSTRETVLKQIREFLEEIVDTQ-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . : : : :.: * ::* : ** ..:: :. : . : :: : : *:. :*.: .:: :: ::: * : ", "identical_positions": 7, "similar_positions": 39, "identity": "6.31%" }, { "cls_id": "homologset.agr.SGD:S000028512", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CR70-1", "uniprot_id": "LAGE3_MOUSE", "id": "Q9CR70-1", "name": "EKC/KEOPS complex subunit Lage3", "aln": "MQTAHTGLSHTADG-----ADGQ-------------------------------------------TSRCCPGNAGTKAVIPSGAHPVARALEASRNSSKSMVP----LTQRPGTRHHRFSLFVPFPTSLEAEIACGSLVPDVEPHRGLVGKELKVSGCMLEVRWIAEDSRLLRLSIINFLDQLSLVVNTIQLFGPPVSC-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14657-1", "uniprot_id": "LAGE3_HUMAN", "id": "Q14657-1", "name": "EKC/KEOPS complex subunit LAGE3", "aln": "MRDADADAGGGADG-----GDGR-------------------------------------------GGHSCRGGVDT-AAAPAGGAPPAHAPGPGRDAASAARG----SRMRP----HIFTLSVPFPTPLEAEIAHGSLAPDAEPHQRVVGKDLTVSGRILVVRWKAEDCRLLRISVINFLDQLSLVVRTMQRFGPPVSR-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2K6Q0-1", "uniprot_id": "A0A0G2K6Q0_RAT", "id": "A0A0G2K6Q0-1", "name": "L antigen family member 3", "aln": "MRDPVEG-LGGRAGVEEG-EDGQRRPQAPDAQAGSRSSATEGDHGNFPRSCPQDSGRLAAPRTPAASGQAALGGPGPGSAAGSGAAAAEAAVIAHGEQAPLGPGPSGDTASATGSRLLEFSVTVPFRTAVEADMARRSLVANARRQQVMVQQEFTVNDSILAVRWTTEDPVLFRISINSFLDQLSLVMRNIQRLEFVAIVKRGRGRSRES---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0R3X9-1", "uniprot_id": "M0R3X9_RAT", "id": "M0R3X9-1", "name": "L antigen family member 3", "aln": "MQGPDEDDSGGRKGLDEGGEDGRHRPQAADAHPRSQSSATEVDHDSSP--------RLNSPQD--ARSQAAPGSSGRGSPAVSGVSAEEAAIIPQDEQVPLLPGPSGDAATTT-SRLLEFSVRVPFSSAVEADMARRSLVANAQRQLLMVPQEYTVNDSILAVRWTTEDPLLFRISINNFLDQLSLVMRNIQHLQFVAFKRR-RERSRNN---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZZR7-1", "uniprot_id": "D3ZZR7_RAT", "id": "D3ZZR7-1", "name": "L antigen family member 3", "aln": "MQDPSGDKVCRAGGEEEG-EDGQHTSRVHDTEANLNRSEVESGHDNTP--------RVNRVRD--FDSQAAPGSLSSRSAIEARLVVEEAAIAPQAEQPPIIPGPSGDAATTAGSRLLEFSVTVPFRTAVEANIACRTLASNVQHQQVMVQQEFTVNDTILTVRWTTEDPVLFRASINNFLDHLSLVMRTIPRPVFIAVVKQGRGRNNEV---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E1JIY8-1", "uniprot_id": "E1JIY8_DROME", "id": "E1JIY8-1", "name": "L antigen family member 3", "aln": "-------------------------------------------------------------------------------------------MMPQIANKP-----------------NESIIRVPFETPRLAEIAYKVLGVDQEPRRNFVKKTLSLENDVLVVHFQSDQVKSLRTAITSFFECLLLCQDTINQFGDSKKEKLIPESNDNAGTHSSSDSP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3E833-1", "uniprot_id": "PCC1_YEAST", "id": "Q3E833-1", "name": "EKC/KEOPS complex subunit PCC1", "aln": "-------------------------------------------------------------------------------------------MTSKREKSLD----------------HTLELKIPFETERQATIATKVLSPDPILKPQDFQVDYSSEKNVMLVQFRSIDDRVLRVGVSSIIDSIKTIVEAMDVLS------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :** : * :* * : : . . . :: *:: : : :* .: .::: : : ", "identical_positions": 7, "similar_positions": 25, "identity": "3.2%" }, { "cls_id": "homologset.agr.SGD:S000028514", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61908-1", "uniprot_id": "CMC4_MOUSE", "id": "Q61908-1", "name": "Cx9C motif-containing protein 4", "aln": "-MP--QKDPCQK--QACE-IQKCLQANNYL---ESKCQAVIQELRKCCARYPKG-----RSLVCSG---FEKEE---------------EEKLAMKSGSK--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56277-1", "uniprot_id": "CMC4_HUMAN", "id": "P56277-1", "name": "Cx9C motif-containing protein 4", "aln": "-MP--QKDPCQK--QACE-IQKCLQANSYM---ESKCQAVIQELRKCCAQYPKG-----RSVVCSG---FEKEE---------------EENLTRKSASK--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7YZN8-1", "uniprot_id": "B7YZN8_DROME", "id": "B7YZN8-1", "name": "Cx9C motif-containing protein 4", "aln": "-MSDTRKDPCKP--NACR-IQACLTKNHYQ---EDKCLDVLEAMRQCCLKWHK------ESLCCSG---IDLEKTY--------LPDASKEKNATGKSNK--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3E7A9-1", "uniprot_id": "CMC4_YEAST", "id": "Q3E7A9-1", "name": "Cx9C motif-containing protein 4, mitochondrial", "aln": "-MS----NPCQK--EACA-IQDCLLSHQYD---DAKCAKVIDQLYICCSKFYNDNGKDSRSPCCPLPSLLELKMK--------------QRKLTPGDS----------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A0G2K2W2-1", "uniprot_id": "A0A0G2K2W2_RAT", "id": "A0A0G2K2W2-1", "name": "Protein p13 MTCP-1", "aln": "MAREDTGAPPTRLWVHCEGVYRDEHQRTWVAAAEEDTATLKARVRRVPVPLGDAS-KPRDLLTSPLPLMWQLYPEGRYMDNKSRLWQIRRHSVVRGAQELLLQLLPET", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : . : : . : : . .. : ... . ", "identical_positions": 2, "similar_positions": 15, "identity": "1.85%" }, { "cls_id": "homologset.agr.SGD:S000028515", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K3C0-1", "uniprot_id": "RNK_MOUSE", "id": "Q8K3C0-1", "name": "Ribonuclease kappa", "aln": "---------------------------------------MASLLCCGPKLAACGIVLSAWGVIMLIMLGIFFNVHSAVLIEDVPFTEKDFENG---PQNIYNLYEQVSYNCFIAAGLYLLLGGFSFCQVRLNKRKEYMVR-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P5S7-1", "uniprot_id": "RNK_HUMAN", "id": "Q6P5S7-1", "name": "Ribonuclease kappa", "aln": "MGWLRPGPRPLCPPARASWAFSHRFPSPLAPRRSPTPFFMASLLCCGPKLAACGIVLSAWGVIMLIMLGIFFNVHSAVLIEDVPFTEKDFENG---PQNIYNLYEQVSYNCFIAAGLYLLLGGFSFCQVRLNKRKEYMVR-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0P442-1", "uniprot_id": "RNKB_DANRE", "id": "Q0P442-1", "name": "Ribonuclease kappa-B", "aln": "---------------------------------------MPSLLFCGPKLAACGIVLSVWGVIMLSMLGIFFSAKSAVLIEDVPFTEEDIRNDKDPPQIIYGLYNQVGINCFIAAAIYVGVGAVSLCQVRLNKRQEYMVT-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0P467-1", "uniprot_id": "RNKA_DANRE", "id": "Q0P467-1", "name": "Ribonuclease kappa-A", "aln": "---------------------------------------MVSLLFCGPKLAACGLVLSIWGVIMLALLGIFFTTHSAILIEDVPLTEEDLHSQDTPPQSVYKLYNQVGYNCFIAAVIYVGIGFLSFCQVRLNKRKEYLVH-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MSF5-1", "uniprot_id": "RNK_DROME", "id": "Q8MSF5-1", "name": "Ribonuclease kappa", "aln": "------------------------------------------MKICGPKLSLCGLIISVWGIVQLVLMGLFFYINSVALIEDLPL-EEEYHSLEDFYAAANRAYNQNAYNCWIAACIYVLTLLLSAQQFYMNSRVTAN-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W286-1", "uniprot_id": "Q9W286_DROME", "id": "Q9W286-1", "name": "", "aln": "-------------------------------------------MFCGRKCCLFCLFMSAWGFLMLNLLGIFFYVQSLMLLESLPL-PHHFPSQEAFKEQADEAYQDVSTRCFVAAVFYLGFVFIAIVAIRRDNKRRKRLYKRGPGHLRFRR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0C5R9-1", "uniprot_id": "RNK_YEAST", "id": "P0C5R9-1", "name": "V-type proton ATPase subunit f", "aln": "---------------------------------------MRPVVSTG--KAWCCTVLSAFGVVILSVIAHLFNTNHESFVGSIND-----------PEDG----PAVAHTVYLAALVYLVFFVFCGFQVYLARRKPSIELR----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .:* :*.: * ::. :* : :: .: . ::** .*: .. . : ", "identical_positions": 8, "similar_positions": 24, "identity": "5.3%" }, { "cls_id": "homologset.agr.SGD:S000028520", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A8MT69-1", "uniprot_id": "CENPX_HUMAN", "id": "A8MT69-1", "name": "Centromere protein X", "aln": "MEGAGAGSGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVR-----QAQAEDALRVDV--DQLEKVLPQLLLDF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C4X1-1", "uniprot_id": "CENPX_MOUSE", "id": "Q8C4X1-1", "name": "Centromere protein X", "aln": "MEGN---SGFRKELVSRLLHLHFRDCKTKVSGDALQLMAEFLRIFVLEAAVRGVW-----QAQAEDLDVVEV--DQLEKVLPQLLLDF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3E829-1", "uniprot_id": "CENPX_YEAST", "id": "Q3E829-1", "name": "Inner kinetochore subunit MHF2", "aln": "--------MLSKEALIKILSQNEGGNDMKIADEVVPMIQKYLDIFIDEAVLRSLQSHKDINGERGDKSPLELSHQDLERIVGLLLMDM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** : ::* : . . *::.:.: :: : * :*: **.:*.: :.: * ::: ::**::: **:*:", "identical_positions": 15, "similar_positions": 35, "identity": "17.05%" }, { "cls_id": "homologset.agr.SGD:S000028698", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CR64-1", "uniprot_id": "KISHA_MOUSE", "id": "Q9CR64-1", "name": "Protein kish-A", "aln": "MSAIFNFQSLLTVILLLICTCAYIRSLAPSILDRNK-TGLLGIFWKCARIGERKSPYVAICCIVMAFSILFIQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LK67-1", "uniprot_id": "A0ABK0LK67_RAT", "id": "A0ABK0LK67-1", "name": "Protein kish", "aln": "MSAIFNFQSLLTVILLLICTCAYVRSLAPSILDRNK-TGLLGIFWKCARIGERKSPYVAICCIVMAFSILFIQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TBQ9-1", "uniprot_id": "KISHA_HUMAN", "id": "Q8TBQ9-1", "name": "Protein kish-A", "aln": "MSAIFNFQSLLTVILLLICTCAYIRSLAPSLLDRNK-TGLLGIFWKCARIGERKSPYVAVCCIVMAFSILFIQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5BJC2-1", "uniprot_id": "KISHA_DANRE", "id": "Q5BJC2-1", "name": "Protein kish-A", "aln": "MSAIFNFQSLLTVILLLICTCAYIRSLTPSLLDKNK-TGFLGIFWKCARIGERKSPYVAFCCIVMALTILFSE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWH8-1", "uniprot_id": "KISH_DROME", "id": "Q9VWH8-1", "name": "Protein kish", "aln": "MSALFNFHSLLSVILLLICTCAYLRSLFPSLIDRNK-TGFMGTFWKLARIGERKSPWVGAACLIMAFTVLFWS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8TGJ3-1", "uniprot_id": "KISH_YEAST", "id": "Q8TGJ3-1", "name": "Protein Kish", "aln": "MSALFNFRSLLQVILLLICSCSYVHGQWPSLLDRYKNHEVLGAFWKMARVGERASPYVSLACILMAISQFNS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:***:*** *******:*:*::. **::*: * .:* *** **:*** **:*. .*::**:: : ", "identical_positions": 37, "similar_positions": 21, "identity": "50.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000125-12", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P12843-1", "uniprot_id": "IBP2_RAT", "id": "P12843-1", "name": "Insulin-like growth factor-binding protein 2", "aln": "MLPRLGGPALPLLLPSLL--LLLLLGAGGCGPGVRAEVLFRCPPCTPERLAACGPPPDAP--------------CAELVREPGCGCCSVCARQEGEACGVYIPRCAQTLRCYPNPGSELPLKALVTGAGTCEKRR---VGATPQQVADSEDDHSEGGLVENHVDGTMNMLGG-SSAGRKPPKSGMKELAVFREKVNEQHRQMGKGAK-HLSLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDDRGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKPIQGAPTIRGDPECHLFYNEQQENDGAHAQRVQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47877-1", "uniprot_id": "IBP2_MOUSE", "id": "P47877-1", "name": "Insulin-like growth factor-binding protein 2", "aln": "MLPRLGGPALPLLLPSLL--LLLLLGAGGCGPGVRAEVLFRCPPCTPERLAACGPPPDAP--------------CAELVREPGCGCCSVCARQEGEACGVYIPRCAQTLRCYPNPGSELPLKALVTGAGTCEKRR---VGTTPQQVADSDDDHSEGGLVENHVDGTMNMLGGGSSAGRKPLKSGMKELAVFREKVNEQHRQMGKGAK-HLSLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDDRGPLEHLYSLHIPNCDKHGRYNLKQCKMSLNGQRGECWCVNPNTGKPIQGAPTIRGDPECHLFYNEQQETGGAHAQSVQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18065-1", "uniprot_id": "IBP2_HUMAN", "id": "P18065-1", "name": "Insulin-like growth factor-binding protein 2", "aln": "MLPRVGCPALPLPPPPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEKRRDAEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKPLKSGMKELAVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECHLFYNEQQEARGVHTQRMQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PTH3-1", "uniprot_id": "IBP2A_DANRE", "id": "Q9PTH3-1", "name": "Insulin-like growth factor-binding protein 2-A", "aln": "MLSYVSCG--------------LLLALVTFHGTARSEMVFRCPSCTAERQAAC-PMLTET--------------CGEIVREPGCGCCPVCARQEGEQCGVYTPRCSSGLRCYPKPDSELPLELLVQGLGRCGRKV----DTEPTGSAEPRE-------VSGEVQDPLDIGLTEVPPIRKPTKD-----SPWKESAVLQHRQQLKSKMKYHKVEDPK--APHAKQSQCQQELDQVLERISKITFKDNRTPLEDLYSLHIPNCDKRGQYNLKQCKMSVNGYRGECWCVNPHTGRPMPTSPLIRGDPNCNQYLDGQEMDPSVDPPN--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. :. ***. .*:*::****.**.** *** * . *.*:*********.**** *** **** ***.. *****:*.*****: ** * * * :: .: * *: : *...*:..::: .. *** *. : ::*.. **** *. : :*:** * . :: *************.: : *:* ***.***********:* *********:** *********:**: : :* *****:*: : : *: .... ", "identical_positions": 138, "similar_positions": 69, "identity": "42.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000125-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88671-1", "uniprot_id": "DLL3_RAT", "id": "O88671-1", "name": "Delta-like protein 3", "aln": "MVSLQVS-SLPQTLILAFL-LPQALPAGVFELQIHSFGPGPGPGTPRSPCNARGP---------CRLFFRVCLKPGVSQEAAESLCALGAALSTSGPVYTEQPGVPAAALSL-PDGLVRVPFLDAWPGTFSLIIETWREQLGERAAGPAWNLLARVAGRRRLAAGAPWARDVQRTGAWELHFSYRARCEPPAVGAACARLCRSRSAPS----RCGPGLRPCTP--FPDECEAPRESLTVCRAGCSPEHGYCEEPDECHCLEGWTGPLCTVPVSTSSCLN----------------------------SRVSGPAGTGCLLPGPG----------------------PCDGNPCANGGSCSETPGS---FECACPRGFYGPRCEVSGVTCADGPCFN--------------------------------------GGLCVGGEDPDSAYVCHCPPAFQGSNCERRVDRCSLQPCQNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGARRCSCALGFGGRDCRERADPCASRPCAHGGRCYAHFSGLVCACAPGYMGVRCEFA----VRPD--GADAVPAAPRGLRQADSQRFLLPPALGLLAAAALAGAALLLIHVRRRGPGRDTGTRLLSGTR----EPSVHTLPDALNNLRLQDGAGDGP------TSSADWNHPEDGDSRSIYVIPAPSIYAREA----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88516-1", "uniprot_id": "DLL3_MOUSE", "id": "O88516-1", "name": "Delta-like protein 3", "aln": "MVSLQVS-PLSQTLILAFL-LPQALPAGVFELQIHSFGPGPGLGTPRSPCNARGP---------CRLFFRVCLKPGVSQEATESLCALGAALSTSVPVYTEHPGESAAALPL-PDGLVRVPFRDAWPGTFSLVIETWREQLGEHAGGPAWNLLARVVGRRRLAAGGPWARDVQRTGTWELHFSYRARCEPPAVGAACARLCRSRSAPS----RCGPGLRPCTP--FPDECEAP----SVCRPGCSPEHGYCEEPDECRCLEGWTGPLCTVPVSTSSCLN----------------------------SRVPGPASTGCLLPGPG----------------------PCDGNPCANGGSCSETSGS---FECACPRGFYGLRCEVSGVTCADGPCFN--------------------------------------GGLCVGGEDPDSAYVCHCPPGFQGSNCEKRVDRCSLQPCQNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGSRRCSCALGFGGRDCRERADPCASRPCAHGGRCYAHFSGLVCACAPGYMGVRCEFA----VRPD--GADAVPAAPRGLRQADPQRFLLPPALGLLVAAGLAGAALLVIHVRRRGPGQDTGTRLLSGTR----EPSVHTLPDALNNLRLQDGAGDGP------SSSADWNHPEDGDSRSIYVIPAPSIYAREDWL--------------IQVLF-------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYJ7-1", "uniprot_id": "DLL3_HUMAN", "id": "Q9NYJ7-1", "name": "Delta-like protein 3", "aln": "MVSPRMSGLLSQTVILALIFLPQTRPAGVFELQIHSFGPGPGPGAPRSPCSARLP---------CRLFFRVCLKPGLSEEAAESPCALGAALSARGPVYTEQPGAPAPDLPL-PDGLLQVPFRDAWPGTFSFIIETWREELGDQIGGPAWSLLARVAGRRRLAAGGPWARDIQRAGAWELRFSYRARCEPPAVGTACTRLCRPRSAPS----RCGPGLRPCAP--LEDECEAP----LVCRAGCSPEHGFCEQPGECRCLEGWTGPLCTVPVSTSSCLS----------------------------PRGPSSATTGCLVPGPG----------------------PCDGNPCANGGSCSETPRS---FECTCPRGFYGLRCEVSGVTCADGPCFN--------------------------------------GGLCVGGADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHFSGLVCACAPGYMGARCEFP----VHPD--GASALPAAPPGLRPGDPQRYLLPPALGLLVAAGVAGAALLLVHVRRRGHSQDAGSRLLAGTP----EPSVHALPDALNNLRTQEGSGDGP------SSSVDWNRPEDVDPQGIYVISAPSIYAREVATPLFPPLHTGRAGQRQHLLFPYPSSILSVK---------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9IAT6-1", "uniprot_id": "DLLC_DANRE", "id": "Q9IAT6-1", "name": "Delta-like protein C", "aln": "------MARVLLTCFFILISSHLGKSSGVFELKVLSFTS------TSSVCKGSSD---------CQIFFRVCLKHSQALILPEPPCTYGTGMSEILSADSISS-----------SAYISVPFNFKWPGIVSLIIETWNAETSDQSTENNNNMISRLATKRRLAISEDWSQDVHLGRQSQLRFSYRVVCDEFYHGEECSDFCRPRNDTFGHFNCDAAGNRICLPGWKGDYCTEP-----ICLSGCSEENGYCEAPGECKCRIGWEGPLCDECTRHPGCLHGTCNQPFQCTCKEGWGGLFCNEDLNFCTNHKPCRNDATCTNTGQGSYTCICKPGFSGKNCE--IETNECDSNPCKNGGSCNDQEND---YTCTCPQGFYGKNCEVSAMTCADGPCFN--------------------------------------GGTCME--KGSGSYSCRCPPGYMGSNCEKKIDRCSSDPCANGGQCLDLGNKATCRCRPGFTGSRCETNIDDCSSNPCQNAGTCVDGINGYTCTCTLGFSGKDCRVRSDACSFMPCQNGGTCYTHFSGPVCQCPAGFMGTQCEYK----QKPTPVNSPALPAALIVSFTLGLITLTLVICAAIVVLRQMRQNHKASSTTVRNNLDSVNNRISLSPTSPLGREKEAFLIPGGPFKVSNKDMALRSTSVDTHSSDKSNYKQKMVDYNLSIDEKHTNNKLEKNSESTLLVPPLNYPKEGVYHPVYIIPEHIEQRVFATEV----------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P10041-1", "uniprot_id": "DL_DROME", "id": "P10041-1", "name": "Neurogenic locus protein delta", "aln": "----MHWIKCLLTAFICFTVIVQVHSSGSFELRLKYFSNDHGRDNEGRCCSGESDGATGKCLGSCKTRFRVCLKHYQATIDTTSQCTYGDVITPILGENSVNLTDAQRFQNKGFTNPIQFPFSFSWPGTFSLIVEAWHDTNNSGNARTNKLLIQRLLVQQVLEVSSEWKTNKSESQYTSLEYDFRVTCDLNYYGSGCAKFCRPRDDSFGHSTCSETGEIICLTGWQGDYCHIP-----KCAKGC--EHGHCDKPNQCVCQLGWKGALCNECVLEPNCIHGTCNKPWTCICNEGWGGLYCNQDLNYCTNHRPCKNGGTCFNTGEGLYTCKCAPGYSGDDCENEIYSCDADVNPCQNGGTCIDEPHTKTGYKCHCANGWSGKMCEEKVLTCSDKPCHQGICRNVRPGLGSKGQGYQCECPIGYSGPNCDLQLDNCSPNPCINGGSCQPSGKCICPAGFSGTRCETNIDDCLGHQCENGGTCIDMVNQYRCQCVPGFHGTHCSSKVDLCLIRPCANGGTCLNLNNDYQCTCRAGFTGKDCSVDIDECSSGPCHNGGTCMNRVNSFECVCANGFRGKQCDEESYDSVTFDAHQYGATTQARADGLTNAQVVLIAVFSVAMPLVAVIAACVVFCMKRKRKRAQEKDDAEARKQNEQNAVATMHHNGSGVGVALASASLGGKTGSNSGLTFDGGNPNIIKNTWDKSVNNICASAAAAAAAAAAADECLMYGGYVASVADNNNANSDFCVAPLQRAKSQKQLNTDPTLMHRGSPAGSSAKGASGGGPGAAEGKRISVLGEGSYCSQRWPSLAAAGVAGACSSQLMAAASVAGSGAGTAQQQRSVVCGTPHM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: : .:* ***:: * *.. *: ****** : . . *: * :: : : .** *** .*:::*:*. .. :: *: :: * . * : .*.:.:*. *: * *: :**.*. . .* * . * * * * ** *:*.*: *.:* * ** *.** . ..*: : . * .* * .* *** ***:* : : * *..*: * ** . :**:* **.: . *: . . : * **..: *:.** .:* * . * *** *:*: : *:* .** *.:*. .:* * ..* *.***:: . *:* ** *:** * *: ** :** * :... * *. *: * :*: * . * . .: : *. . . . .. : . . . : : .: : ", "identical_positions": 127, "similar_positions": 134, "identity": "15.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000128-11", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5NSW5-1", "uniprot_id": "DBX1_RAT", "id": "Q5NSW5-1", "name": "Homeobox protein DBX1", "aln": "---------------------------------------------------------------------------------------------------------------------------MMFPGLLAPPAGYP----SLLRPTPTLTLP----------------------------QSLQSAFSGHSSFLVEDLIRISRP--------------------------------------PTYLPRSIP------------------------TASLSPPRQEAPTALADSGTSDLGSPGSGSRRG-----------SSPQTALSPASEPTFLKFGVNAILSSA---------------PRRETSPALLQSPPPKTFAFPYFEG--------SFQPFIRSSYFPASSSVVPIPG--TFSWPLAARGKPRRGMLRRAVFSDVQRKALEKTFQKQKYISKPDRKKLASKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQK--------------GPGDEEED----SPGASLAYHAPPDPRHL-------------------------------------LEGPLPASPAHSSSPGKPSDFSDSD--------------------------------------------------------------------------------------------------EDEEGEEDEEITVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52950-1", "uniprot_id": "DBX1_MOUSE", "id": "P52950-1", "name": "Homeobox protein DBX1", "aln": "---------------------------------------------------------------------------------------------------------------------------MMFPGLLAPPAGYP----SLLRPTPTLTLP----------------------------QSLQSAFSGHSSFLVEDLIRISRP--------------------------------------PTYLSRSIP------------------------AASLSPPSQEAPAALADSGTSDLGSPGSGSRRG-----------SSPQTALSPASEPTFLKFGVNAILSSA---------------PRRETSPALLQSPPPKTFAFPYFEG--------SFQPFIRSSYFPASSSVVPIPG--TFSWPLAARGKPRRGMLRRAVFSDVQRKALEKTFQKQKYISKPDRKKLASKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQK--------------GPGDEEED----NPGARLAYHAPADPRHL-------------------------------------LEGPLPASPAHSSSPGKPSDFSDSD--------------------------------------------------------------------------------------------------EDEEGEEDEEITVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NMT0-1", "uniprot_id": "DBX1_HUMAN", "id": "A6NMT0-1", "name": "Homeobox protein DBX1", "aln": "---------------------------------------------------------------------------------------------------------------------------MMFPGLLAPPAGYP----SLLRPTPTLTLP----------------------------QSLQSAFSGHSSFLVEDLIRISRP--------------------------------------PAYLPRSVP------------------------TASMSPPRQGAPTALTDTGASDLGSPGPGSRRG-----------GSPPTAFSPASETTFLKFGVNAILSSG---------------PRTETSPALLQSVPPKTFAFPYFEG--------SFQPFIRSSYFPASSSVVPIPG--TFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQK--------------GPGNEEEEEGPGSPSHRLAYHASSDPQHLRD---------------------------------PRLPGPLPPSPAHSSSPGKPSDFSDSE--------------------------------------------------------------------------------------------------EEEEGEEQEEITVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PTU0-1", "uniprot_id": "DBX1B_DANRE", "id": "Q9PTU0-1", "name": "Homeobox protein DBX1-B", "aln": "---------------------------------------------------------------------------------------------------------------------------MMLPSVIAPPAMYP----SFLRPSSALSLP----------------------------PALQSAFTTHSSFLVEDLLRISRP--------------------------------------AAFMHRSIP------------------------SPSASPPATGVTTLNTTSSAVHVAMSTALAKRS-----------SSPQTSIS--SDPNYLKFGVNAILAST---------------TRNASPPPPVQGMNAKTFPFPCFDG--------SFHPFIRASYFPASSSAVPIPG--TFAWPLTARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLATKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKMNPNPDLSDVGKR--------------FEHEAVLR-----ESPRAPFCQSRGDHEFN-------------------------------------ADLHFKSPSISS---KHSDFSES---------------------------------------------------------------------------------------------------------EDEEITVS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W064-1", "uniprot_id": "Q9W064_DROME", "id": "Q9W064-1", "name": "", "aln": "MSTAFLVDSLLHAQQTYTESQLKSSLSEMLLSRRSATGTDAADPADQPTESCGCSKLRGYKCDKCREIRAESVESIEEMDEDDGSSSADEIVADIGSVEGEEPHMDLDEELEEELADVDEPVSIKLPKVEPKETSMPTVGNTILKDTNSKPILKFSVSAILGDTREGVRVRNEFMQPQHIWPYLQQNFMQQHSHQYQQHHQQQQPHSHPQHQPLAVPGHQHSHPHSHHHHHHHPGAGHAHFPHPAFLTHQLPPHQHHQQQQHVQQQHPGNSCQPQTASSSSSPGSTISDSDNNHGASTANGNGSGTGNSGQDARPHELANSNPDEDSSASRRLTQDKQQQQQLLGAGGTGGGGGGGHGHGHPTPPPPPPPPVIAKPMPSRPTPFLPHTLNHPHLHSLLAHCRNPYMSVGAQVFPLPPGQGFPWAHSTRGKPRRGMMRRAVFSDSQRKGLEKRFQQQKYISKPDRKKLAERLGLKDSQVKIWFQNRRMKWRNSKERELLASGGSRDQTLPNKNNPNPDLSDAKCDRPLTPLSPSLLSPNGSATPPPPGAVAKDEPPTAAVTPKSPQSVSSRSSPSVGYGLQISSPPPLLTSLKMGDQSASATPTPLPGTTVSSAAASPPGVTASEFQAKINAEMQKQLVAADLKFKLENSIQEAKQRRFEQLQQQLHHSPHFSAMREVELAAAAAAAQLHHHHQQQQQQQQQQHAQQQHAQQQHQGGSEFMKLYYDDYDDSNSDSDEEISVT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* : . : * ::*: : : .: **. * : *. :: : .:* .::: :.:* :.* *.* . .: . : .. ..* * . * : :*.: . ..*. : . : . * : *: .. * .*:...:...*:* *.*. ::********:******* ***.*** **:************* :****************************:***.*:****.* **:*****. . . . : . . *.: *. . *:*. . .:***:*:", "identical_positions": 113, "similar_positions": 97, "identity": "15.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000128-8", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5NSW5-1", "uniprot_id": "DBX1_RAT", "id": "Q5NSW5-1", "name": "Homeobox protein DBX1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMFPGLLAP-------------------------PAGYPSLLRPTPTLTLPQSLQSAFSG---------HSSFLVEDLIRISRP----------PTYLPRSIPTASLSPPRQEAPTALADSGTSDLGSPGSGSRRG-----------SSPQTALSPASEPTFLKFGVNAILSSA-----------------PRRETSPALLQSPP-------PKTFAFPYFEGSFQPFIRSSYFPASSSVVPIPG--TFSWPLAARGKPRRGMLRRAVFSDVQRKALEKTFQKQKYISKPDRKKLASKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQK--------------GPGDEEED----SPGASLAYHAPPDPRHL-------------------------------------LEGPLPASPAHSSSPGKPSDFS--------------------------------------------------------------------------------------------------DSDEDEEGEEDEEITVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52950-1", "uniprot_id": "DBX1_MOUSE", "id": "P52950-1", "name": "Homeobox protein DBX1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMFPGLLAP-------------------------PAGYPSLLRPTPTLTLPQSLQSAFSG---------HSSFLVEDLIRISRP----------PTYLSRSIPAASLSPPSQEAPAALADSGTSDLGSPGSGSRRG-----------SSPQTALSPASEPTFLKFGVNAILSSA-----------------PRRETSPALLQSPP-------PKTFAFPYFEGSFQPFIRSSYFPASSSVVPIPG--TFSWPLAARGKPRRGMLRRAVFSDVQRKALEKTFQKQKYISKPDRKKLASKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQK--------------GPGDEEED----NPGARLAYHAPADPRHL-------------------------------------LEGPLPASPAHSSSPGKPSDFS--------------------------------------------------------------------------------------------------DSDEDEEGEEDEEITVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NMT0-1", "uniprot_id": "DBX1_HUMAN", "id": "A6NMT0-1", "name": "Homeobox protein DBX1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMFPGLLAP-------------------------PAGYPSLLRPTPTLTLPQSLQSAFSG---------HSSFLVEDLIRISRP----------PAYLPRSVPTASMSPPRQGAPTALTDTGASDLGSPGPGSRRG-----------GSPPTAFSPASETTFLKFGVNAILSSG-----------------PRTETSPALLQSVP-------PKTFAFPYFEGSFQPFIRSSYFPASSSVVPIPG--TFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQK--------------GPGNEEEEEGPGSPSHRLAYHASSDPQHLRD---------------------------------PRLPGPLPPSPAHSSSPGKPSDFS--------------------------------------------------------------------------------------------------DSEEEEEGEEQEEITVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PTU1-1", "uniprot_id": "DBX1A_DANRE", "id": "Q9PTU1-1", "name": "Homeobox protein DBX1-A", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMIPSVIAP-------------------------PAIYSAFMRP------AASLHSPFPA---------HPSFLVEDLLRINRP----------SGFLSQTAHSPCASPPNSTPLSIPDNCRILDRVSPGITEKHGP----------CSPKTPVS-SKDPTYLKFGVSAILAPS-----------------PKKATSPPSVHSIH-------PKGFSVPYFDGSFCPFVRSSYFPAPSSVVPIPG--TFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKTNPHPDLSDVGKK--------------SSEDEDED------DACAPSHFCLSPRRV------------------------------------------MSNSTDSSITFKHSDFS--------------------------------------------------------------------------------------------------ESED--------EITVS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W064-1", "uniprot_id": "Q9W064_DROME", "id": "Q9W064-1", "name": "", "aln": "MSTAFLVDSLLHAQQTYTESQLKSSLSEMLLSRRSATGTDAADPADQPTESCGCSKLRGYKCDKCREIRAESVESIEEMDEDDGSSSADEIVADIGSVEGEEPHMDLDEELEEELADVDEPVSIKLPKVEPKETSMPTVGNTILKDTNSKPILKFSVSAILGDTREGVRVRNEFMQPQHIWPYLQQNFMQQHSHQYQQHHQQQQPHSHPQHQPLAVPGHQHSHPHSHHHHHHHPGAGHAHFPHPAFLTHQLPPHQHHQQQQHVQQQHPGNSCQPQTASSSSSPGSTISDSDNNHGASTANGNGSGTGNSGQDARPHELANSNPDEDSSASRRLTQDKQQQQQLLGAGGTGGGGGGGHGHGHPTPPPPPPPPVIAKPMPSRPTPFLPHTLNHPHLH-SLLAHCRNPYMSVGAQVFPLPPGQGFPWAHSTRGKPRRGMMRRAVFSDSQRKGLEKRFQQQKYISKPDRKKLAERLGLKDSQVKIWFQNRRMKWRNSKERELLASGGSRDQTLPNKNNPNPDLSDAKCDRPLTPLSPSLLSPNGSATPPPPGAVAKDEPPTAAVTPKSPQSVSSRSSPSVGYGLQISSPPPLLTSLKMGDQSASATPTPLPGTTVSSAAASPPGVTASEFQAKINAEMQKQLVAADLKFKLENSIQEAKQRRFEQLQQQLHHSPHFSAMREVELAAAAAAAQLHHHHQQQQQQQQQQHAQQQHAQQQHQGGSEFMKLYYDDYDDSNSDSDEEISVT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* * : * . : .: * . * : . *.:**..:* .: . :. :.. *.* . : . * .. .* * : * * . :*... * ..* :. *: : *::. *: .. *..*:.. :.*.*:* *.*. ::********:******* ***.*** **:************* :****************************:***.*:****.* **:*****. . .. . .*: : ...: *. . *:*. :. : **:*:", "identical_positions": 116, "similar_positions": 90, "identity": "15.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000201-13", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23352-1", "uniprot_id": "KALM_HUMAN", "id": "P23352-1", "name": "Anosmin-1", "aln": "-----MVPG--------VPGAVLTLCLWLAASSGCLAAGPGA-----------AAARRLDESLSAGSVQRARCASRCLSLQITRISAFFQHFQNNGSLVWCQNHKQCSKCLEPCKESGDLRKHQCQSFCEPLFPKKSYECLTSCEFLKYILLVKQGDCPAPEKASGFAAACVESCEVDNECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELQSGQLEVKWSSKFNISIEPVIYVVQRRWNYGIHPSEDDATHWQTVAQTTDERV-------QLTDIRPSRWYQFRVAAVNVHGTRGFTAPSKHFRSSKDPSAPPAPANLRLANSTVNSDGSVTVTIVWDLPEEPDIPVHHYKVFWSWMVSSKSLVPTKKKRRKTTDGFQNSVILEKLQPDCDYVVELQAITYWGQTRLKSAKVSLHFTSTHATNNKEQLVKTRKGGIQTQLPFQRRRPTRP-LEVGAPFYQDGQLQVKVYWKKTEDPTVN---RYHVRWFPEACAHNRTTGSEASSGMTHENYIILQDLSFSCKYKVTVQPIRPKSHSKAEAVFFTTPPCSALKGKSHKPVGCLGEAGH-VLSKVLAKPENLSASFIVQDVNITGHFSWKMAKAN-LYQPMTGFQVTWAEVTTESRQNSLPNSIISQSQILPSDHYVLTVPNLRPSTLYRLEVQVLTPGGEGPATIKTFRTPELPPSSAHRSHLKHRHPHHYKPSPERY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IDR3-1", "uniprot_id": "A0AC58IDR3_DANRE", "id": "A0AC58IDR3-1", "name": "", "aln": "MSTRCFCRGSNSEDDWRRTGSIWTMAAGDTEMRKGQTQTPAAGVMFTSKRLTVSVARRTEEAESLEKMESARCVSRCLTLHITQITAAFRHLQNDRVLGWCENHRRCSQCLQPCKELWETRRALSPKTCE------HHECVTSAEFLRSLRVQKQGDCPPAQRASGFAAACVESCARDHECSGVKKCCSNGCGHTCQSPANLFKGVPLKPRRDISFSEDHQGHVKVTWMSKFNVSVEPVLYVLQRRWNHGIHPSEDEATAWQTVLMTMEDRS-------VLKDIRPHRWYQFRVSAVNSQGTRGFTTPSKHFFSVRDPLPPETPQNARTANQTLHPDGTVSVLVLWETPRESDLVLHHYKVTWSPRGTPS---SSQSRAGRVTDGDVTQMELQGLQPNTPYTAQIQAISYWGQNRLKSSRAHVSFTTTSQNS-----ATSSNGEFSNELPVSHSSPSVLRLEAAAPHYHDNQLQVKVFWKSRVQESQKDSSSYILRWYPEVCSHNVTK--DEKTATVQGTHYVITGLLFACKYRVAVKPVAEQ--RSEVTTSVTTPLCLSLMGRRKKPAACAREERHPQLKKALRRPEKLAVLFQPVNGSLQALFSWQLSPESSGQTPSSGFQFSWVKVSSGSSNG----SLISQTHVLPPDQLSLTVDALQPSSVYRVQVQVLSEAGNGPSVAKTLHTPALN-STIH-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCC7-1", "uniprot_id": "Q9VCC7_DROME", "id": "Q9VCC7-1", "name": "", "aln": "------------------MGSMQVALLALLVLGQLFPSAVAN----------------------GSSSYSSTSTSASNQLQRQKLAHWFRDSND------VKDKILELQCLAKCGSNPTTKAGREQ-------------CLN-KCIQELLLGPRAGSCPKIGRQSRARLSCLDNCQYDHECPEVQKCCPSSCGPMCVEPLGVRNNTQLPPIPKILYFRRSRG-HAVDLKIESSLLVYYFHVEVRSHIGRHFAARKLGPWQWQKVEKTMEENIGHSKHTYIFFHMRPGRWYEVRVAAVNAYGFRGYSEPSDPFPSTGNPKPPKSPNDSKIIGKQFDG-RYMTLKLVWCPSK-SNLPVEKYKITWSLYVNSA---KASMITNSSYVKDTHQFEIKELLPNSSYYIQVQAISYLGSRRLKSEQWSMLFNTT----------------LQPLEPIT----------------------------------------------PLQCSGNGNR-----------RRHHHTSSSMSSERATTSEPVALN---------------------EVSPTITNRTSAAATYEVGFRLNRKFGMIVQILGFQPHKEKVYELCPQETNCEQRE-FRAIRAKKDP-----------LEFSKLKYNTTYVLRIPRSSPNSVLDDSRNVFTFTTPKCENFR-KRFPKLQIKCSD-------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: . . . . : ..* . *: ::: *:. :: ::: :** * . : *:. : . : : *.** : * :*::.* *:**. *:***...** * * : :.. * * .: : . * * : .: : . :: : . : . : . **.* * ::. : .:** ***:.**:*** * **:: **. * * :* .* :* : : .. .. ::: ::* .. .:: :.:**: ** .. :. .. :: * *: * ::***:* *. **** : : *.:* :. *. * *: * . . ::.: .: :*: : .*. . : .::. . . . :::. . *: .: . :. ::: * : *.:: . :*:: : : * * . . ", "identical_positions": 84, "similar_positions": 168, "identity": "11.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000201-9", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23352-1", "uniprot_id": "KALM_HUMAN", "id": "P23352-1", "name": "Anosmin-1", "aln": "MVPGVPGAVLTLCLWLAASSGCLAAGPGAAAARRLDESLSAGSVQRARCASRCLSLQITRISAFFQHFQNNGSLVWCQNHKQCSKCLEPCKESGDLRKHQCQSFCEPLFPKKSYECLTSCEFLKYILLVKQGDCPAPEKASGFAAACVESCEVDNECSGVKKCCSNGCGHTCQVPKTLYKGVPLKPRKELRFTELQSGQLEVKWSSKFNISIEPVIYVVQRRWNYGIHPSEDDATHWQTVAQTTDE-------RVQLTDIRPSRWYQFRVAAVNVHGTRGFTAPSKHFRSSKDPSAPPAPANLRLANSTVNSDGSVTVTIVWDLPEEPDIPVHHYKVFWSWMVSSKSLVPTKKKRRKTTDGFQNSVILEKLQPDCDYVVELQAITYWGQTRLKSAKVSLHFTSTHATNNKEQLVKTRKGGIQTQLPFQRRRPTRPLEVGAPFYQDGQLQVKVYWKKTEDPTVNRYHVRWFPEACAHNRTTGSEASSGMTHENYIILQDLSFSCKYKVTVQPIRPKSHSKAEAVFFTTPPCSALKGKSHKPVGCLGEAGHVLSKVLAKPENLSASFIVQDVNITGHFSWKMAKANLYQPMTGFQVTWAEVTTESRQNSLPNSIISQSQILPSDHYVLTVPNLRPSTLYRLEVQVLTPGGEGPATIKTFRTPELPPSSAHRSHLKHRHPHHYKPSPERY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PBX0-1", "uniprot_id": "A0A8M1PBX0_DANRE", "id": "A0A8M1PBX0-1", "name": "", "aln": "MRDGLTGLCIGIILLLNG---------GLVVMRRQDSSSALGSIFRTRCAARCLSLHSTRIALSPRHFQSNGSLGWCQSHKQCAKCLEPCKDSWELKDGPCRDLCEHAFPKRHGECVTSCEFLRSVMVVKQGDCPPPERASGFAAACVEGCEEDGECSGQKKCCPNGCGHTCQSPKNLYRGAPLKPRKELVFEELESGVLEVRWSSKFNVSAEPVLNVLQRRWNYGIHPSEDGATEWQVVARTSEE-------RVWLTDIRPGRWYQFRVAAVNVHGTRGYTTPSRHFRSSKDPPPPPAPSDLHVSDMTFGADHSASVRLSWSISADLDIPVNHYKLSWS---SSDHTLPPKLKKRETVNGDSTYAELDDLRENGSYTVELQAVSYWGQVPLKSSKAILQFTTSQTQSDLEPTVS----------PVFIKPQSDLLDVGTPFYQDGQLQVRVYWKK-KDPTVNRYRVQWAPEFCSHNRSRTQEK--LITQENFASLSGLQFSCKYKVIIQPVGLKGRAQVESTTFYTPSCATIQSKSPKPIPCSSVP-VVQPKVLVKAENLTAAFSVYLGNVTGLFSWVVAMPQQPQQVTGYQVTWAEVITESRRNNLPNSLISQSQILPPERNILVVSGLQLASLYRLEVQVITAAGQGPATSRTFQTPTHSKPVLH--YKPRIKKHHLRSVIERH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCC7-1", "uniprot_id": "Q9VCC7_DROME", "id": "Q9VCC7-1", "name": "", "aln": "--MGSMQVALLALLVLG--------------QLFPSAVANGSSSYSSTSTSASNQLQRQKLAHWFRDSND------VKDKILELQCLAKCGSNPTTKAG-------------REQCLNKC-IQELLLGPRAGSCPKIGRQSRARLSCLDNCQYDHECPEVQKCCPSSCGPMCVEPLGVRNNTQLPPIPKILYFRRSRG-HAVDLKIESSLLVYYFHVEVRSHIGRHFAARKLGPWQWQKVEKTMEENIGHSKHTYIFFHMRPGRWYEVRVAAVNAYGFRGYSEPSDPFPSTGNPKPPKSPNDSKIIGKQFDG-RYMTLKLVWCPSKS-NLPVEKYKITWS---LYVNSAKASMITNSSYVKDTHQFEIKELLPNSSYYIQVQAISYLGSRRLKSEQWSMLFNTTLQP----------------------------LEPITPLQCSGNGNRRRHHHTSSSMSSERATTSEPVALNEVSPTITNRTSAAATYE-----VGFRLNRKFGMIVQILG--FQPHKEKVYELCPQETNCEQREFRAIRAKKDP---------------LEFSKLKYNTTYVLRIPRSSPNSVLDDSRNVFTFTTPKCENFRKRFPKLQIKCSD----------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * * . .* : .:: . .*: ::: :. :. :.: :** * .. : :*:..* : . :: : *.** : * :*::.*: * **. :***...** * * : ... * * :: : . . * * . : .: . :: : . : . : .. .** * :* :* : .:**.***:.******.:* **:: ** * *: :* .* :* : :: . ... :: : * . . ::**.:**: ** .. ..: :..* : .* :::**::* *. *** : : *.:: *: :*: .*: : : : :. .. : :* . . : .. * * .: :. *: : :* : :.: * . * : : :. :.: . . * * * : : .: : .*:: *. :: :*: *. *: ", "identical_positions": 91, "similar_positions": 178, "identity": "13.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000208-18", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P32362-1", "uniprot_id": "DCUP_RAT", "id": "P32362-1", "name": "Uroporphyrinogen decarboxylase", "aln": "----NGLGL-QNFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCELTLEPVRRFP--LDAAIIFSDILVVPQALAMEVTMVPGKGPSFPEPLREERDLERLRD-PAAVASELGYVFQAITLTRQQLAGRVPLIGFAGAPWTLMTYMVEGGSFKTMAQAKRWLYQKPVASHKLLGILTHALVPYLIGQVAAGAQALQLFESHAGHLGSELFSKFALPYIRDVAKRVKAGLQKAG-LTRMPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKKAREPVGKTVTLQGELDPCALYASEEEIGRLVQQMLNDFG--PQRYIANLGHGLYPDMDPEHVGAFLDAVHKHSRLLRQN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70697-1", "uniprot_id": "DCUP_MOUSE", "id": "P70697-1", "name": "Uroporphyrinogen decarboxylase", "aln": "-MEANGFGL-QNFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCELTLQPLRRFP--LDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREERDLERLRD-PAAAASELGYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGSSSTMAQAKRWLYQRPQASHKLLGILTDVLVPYLIGQVAAGAQALQLFESHAGHLGTELFSKFALPYIRDVAKRVKAGLQKAG-LAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARERVGKAVTLQGNLDPCALYASEEEIGRLVQQMLDDFG--PQRYIANLGHGLYPDMDPERVGAFVDAVHKHSRLLRQN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06132-1", "uniprot_id": "DCUP_HUMAN", "id": "P06132-1", "name": "Uroporphyrinogen decarboxylase", "aln": "-MEANGLGP-QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCELTLQPLRRFP--LDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRD-PEVVASELGYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGGSSTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAG-LAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIGQLVKQMLDDFG--PHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PTS2-1", "uniprot_id": "DCUP_DANRE", "id": "Q9PTS2-1", "name": "Uroporphyrinogen decarboxylase", "aln": "MMDKDSFILPKDFPELRNDTFLRAARGEEIEHIPVWCMRQAGRYLPEFRESRAGKDFFETCRSPEACCELTLQPLRRFP--FDAAIIFSDILVVPQAMGMEVQMCPGKGPTFPEPLKEPEDLQRLKT-QVDVYSELDYVFKAITLTRHKIEGKVPLIGFTGAPWTLMSYMIEGGGSATHSKAKRWLYRYPEASHKLLSQLTDVIVEYLLGQVKAGAQALQVFESHTGCLGPVEFKEFSLPYLRDIARRVKDKIKESG-LDNVPMIVFAKDGHYGLEDLSESAYEVVGLDWTIDPRSARVRTGGKVSLQGNMDPCALYGTKESISEIVRRMLEGFG--TKGYIANLGHGLYPDMDPENVGAFVEAVHNHSRQLLKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V595-1", "uniprot_id": "DCUP_DROME", "id": "Q9V595-1", "name": "Uroporphyrinogen decarboxylase", "aln": "------MKDAKPFPVLKNDNLLRAARGEVVDRVPVWVMRQAGRYLPEFQELRKHHDFFTVCRTPELACEVTMQPLRRFD--LDASIIFSDILVIPQALGLTVEMHAGVGPVLPQPIVVPEDLKRLT--PDGALSRLSYVGDAITMMRHKLEGRVPLIGFTGAPWTLMGYMIEGGGSKTMSKAKAWLNEHPEDSKLFLNLLTDAIVDYLEMQVKAGAQMLQVFESSAEHLSKEQFLQWCVPYLKRIRDELVDRLTKKA-IPVVPMTLFAKGAGHSLKEQSELGYDVIGLDWTVDPLEARNLVGPNITLQGNLDPQDMYRDPDELRNLTTEMVHKFG--KSRYIANLGHGITPQTPITSMEVLVEAVHKAL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32347-1", "uniprot_id": "DCUP_YEAST", "id": "P32347-1", "name": "Uroporphyrinogen decarboxylase", "aln": "------MGN---FPAPKNDLILRAAKGEKVERPPCWIMRQAGRYLPEYHEVKNNRDFFQTCRDAEIASEITIQPVRRYRGLIDAAIIFSDILVIPQAMGMRVEMLEGKGPHFPEPLRNPEDLQTVLDYKVDVLKELDWAFKAITMTRIKLDGEVPLFGFCGGPWTLMVYMTEGGGSRLFRFAKQWINMYPELSHKLLQKITDVAVEFLSQQVVAGAQILQVFESWGGELSSVDFDEFSLPYLRQIAERVPKRLQELGIMEQIPMIVFAKGSWYALDKLCCSGFDVVSLDWSWDPREAVKINKNRVTLQGNLDPGVMYGSKEVITKKVKQMIEAFGGGKSRYIVNFGHGTHPFMDPDVIKFFLEECHRIGSK----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** :** :**** ** : * * **********::* : :*** .** .* ..*:*::*:**: :**:********:***:.: * * * ** :*:*: .**: : . ..*.:. .***: * :: *.***:** *.***** ** ***. ** *: * *: :* :*.. * :* ** **** **:*** *. * ::.:**:: : .: : : . : :** :***.. ..*.. . .::*:.***: * .* ::***::** :* : : . . .*:. ** **.*:*** * : ::: *. ", "identical_positions": 131, "similar_positions": 100, "identity": "34.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000208-20", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H2W2-1", "uniprot_id": "MIXL1_HUMAN", "id": "Q9H2W2-1", "name": "Homeobox protein MIXL1", "aln": "MATAESRALQFAEGAAFPAYRAPHAGGALLPPPSPAAALLPAPPAGPGPATFAGFLGRDPGPAPPPPASLGSPAPPKGAAAPSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPESRIQVWFQNRRAKSRRQSGKSFQPLAR---------------------------------------------------------------------------------------------PEIILNHC----------------------APGTETKCLKPQLPLEVDVNCLPE-PNGVGGGIS--DSSSQGQNFETCSPLSEDIGSKLDS----WEEHIFSAFGNF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WUI0-1", "uniprot_id": "MIXL1_MOUSE", "id": "Q9WUI0-1", "name": "Homeobox protein MIXL1", "aln": "MAAAGSQQLQFAEGAAFPIFPAAHPGGQLLPAMRPASGLPAAPHDSRAPAATQCFPNRDSSPTAQTPAGLDPPGPSKGSAAPSAPQRRKRTSFSSEQLQLLELVFRQTMYPDIHLRERLAALTLLPESRIQVWFQNRRAKSRRQSGKSFQPLSS---------------------------------------------------------------------------------------------RRGVFLHCP---------------------APGTEARCLKPQLPLEADVNHVPD-PSMTGGGVC--TSGS--QSFETYSSLSEDIGSKLDS----WEEHIFSALGNF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TYX1-1", "uniprot_id": "Q5TYX1_DANRE", "id": "Q5TYX1-1", "name": "", "aln": "MAVVHGN-LGNGHLKQFQLFPN---------------------------ADMERRTGMHTSDYVLQDRMKFLDGASRADNVSLFTHRRKRTNFTQQQIDVLEKVYLDTKYPDIYLREKLEALTGLPESRIQVWFQNRRAKSRRQVGISIPNKTSGNILTPNNLLMHQFTTHQNHSGLENLQRTSTFTADSFHQQLINSSEEKISTIKGDIYDPTTIPCMFSRTQENPIKTDHLSVVVPRSYTQQYPKEHEQFTHSANHAKSTMKQFLVEYDNFPPNKTIGPEMKVVIPPLPSQSNFMMSSSSPKHIACSVQNMSVQTQPELFATFSPIRASEAVEFSDSDSDWERDAMSGFNGFI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.. .. * .. * : * . ... ...:. .. .:*****.*: :*:::** *: * ****:***:* *** ******************** * *: : . : *. : *.* : : * ** : :. .. *. . .: : : * * *.: . . ::.. **.. :*.:..* ", "identical_positions": 63, "similar_positions": 64, "identity": "17.75%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000208-21", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QWT9-1", "uniprot_id": "KIFC1_MOUSE", "id": "Q9QWT9-1", "name": "Kinesin-like protein KIFC1", "aln": "----------------------------MDVQAQRPPLLEVKRNVELKAALVKSSSRVPLSASRLKRGPDQMEDALEPAKKRTRVMGAVTKVDTSRPRGPLLSTVSQTQGHTAAQKGPKKTGPRGCSAIGTV-LRSQKPVPAAPAQKPGTSTAPVVVG-KRAGKRPAWDLKGQLCDLNEELKRYREKTQTLE----LENRGLREQLREVQEQATTLGTERNTLEGELASVRSRAEQDQQRLETLSARVLELEEC-------------LGTRERLLQELQGERLQLQEERSTLSTQLEEQERRFQATEAALSSSQEEVVCLRQ----------------------------KTEAQVTLLAEQGDRLYGLEMERRRLHNQLQELKGNIRVFCRVRPVLEGESTPSPGFLVFPPGPAGPSDPPTGLSLSRSDDRRSTLTGAPAPTVRHDFSFDRVFPPGSKQEEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPRGDPQLEGLIPRAMRHLFSVAQEMSGQGWTYSFVASYVEIYNETVRDLLATGPRKGQGGECEIR---RASPGSEELTVTNARYVPVSCEKEVEALLHLAHQNRAVAHTAQNKRSSRSHSVFQLQISGEHAARGLQCGAPLNLVDLAGSERLDPGLHLGPGERDRLRETQAINSSLSTLGLVIMALSNKES---HVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANKK--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PUA5-1", "uniprot_id": "E9PUA5_MOUSE", "id": "E9PUA5-1", "name": "Kinesin-like protein", "aln": "----------------------------MDVQAQRK-GREGKRNVELKAALVKSSSRLPLSASSLKRGPDQMEDALEPAKKRTRVMGAVTKVDTSRPRGPLLSTVSQTQGHNAAQKGPKKTGPGGCSAVGTV-LRSQKPAPAAPA-KPGTSTAPVVVG-KRAGKRPAWDLKGQLCDLNEELKRYREKTETLE----LENRGLREQLREVQEQATTLGTERNTLEGELASVRSRAEQDQQRLETLSARVLELEEC-------------LGTRERLLQELQGERLQLQEERSTLSTQLEEQERRFQATEAALSSSQEEVVCLRQ----------------------------KTEAQVTLLAEQGDRLYGLEMERRRLHNQLQELKGNIRVFCRVRPVLEGESTPSPGFLVFPPGPAGPSDRPTGLSLSRSDDRRSTLTGAPAPTVRHDFSFDRVFPPGSKQEEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPRGDPQLAGLIPRAMRHLFSVAQEMSGQGWTYSFVASYVEIYNETVRDLLATGPRKGQGGECEIR---RASPGSEELTVTNARYVPVSCEKEVEALLHLAHQNRAVAHTAQNKRSSRSHSVFQLQISGEHAARGLQCGAPLNLVDLAGSERLDPGLPLGPGERDRLRETQAINSSLSTLGLVIMALSNKES---HVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANKK--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XI63-1", "uniprot_id": "KIFC1_RAT", "id": "Q5XI63-1", "name": "Kinesin-like protein KIFC1", "aln": "----MRGRGSRDTGTQSAAFASRPVRTTVDMQAQRAPLMEVKRNLELSTTLVKSSSRLPLPGSRLKRGPDQMEDGLEPAKKRTRGMGTVTKVDTSRPRGPPLSAVS-----TAAQKGPRKTGPRGCSAVGPV-LRNQKPAPAAPAQKPGTSTAPAVAG-KKPGKRPAWDLKGQLCDLHEELKQYREKTQTLD----RENQGLREQLREVQEQATTLGTERNTLEEELASVRRRAEQSQQKLETLGARVLELEEC-------------LGTKERLVQELQTERLQLQEERSTLSTQLEEREREFQASEAALSSSRAEVLCLRQ----------------------------KTAAQVTLLAEQGDRLYGLEMERRRLHNQLQELKGNIRVFCRVRPVLEGESTPSPGFLVFPPGPAGPSDPPTRLCLSRSDDRRSTLTRAPAAATRHDFSFDRVFPPGSKQEEVFEEISMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPRGDPQLEGLIPRAMRHLFSVAQEMSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGGDCEIR---RAGPGSEELTVTNARYVPVSCEKEVEALLHLAQQNRAVARTAQNERSSRSHSVFQLQISGEHAARGLQCGAPLNLVDLAGSERLDPGLTLGPGERDRLRETQAINSSLSTLGLVIMALSNKES---HVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANKK--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BW19-1", "uniprot_id": "KIFC1_HUMAN", "id": "Q9BW19-1", "name": "Kinesin-like protein KIFC1", "aln": "------------------------------MDPQRSPLLEVKGNIELKRPLIKAPSQLPLSGSRLKRRPDQMEDGLEPEKKRTRGLGATTKITTSHPRVPSLTTVPQTQGQTTAQKVSKKTGPRCSTAIATG-LKNQKPVPAVPVQKSGTSGVPPMAGGKKPSKRPAWDLKGQLCDLNAELKRCRERTQTLD----QENQQLQDQLRDAQQQVKALGTERTTLEGHLAKVQAQAEQGQQELKNLRACVLELEER-------------LSTQEGLVQELQKKQVELQEERRGLMSQLEEKERRLQTSEAALSSSQAEVASLRQ----------------------------ETVAQAALLTEREERLHGLEMERRRLHNQLQELKGNIRVFCRVRPVLPGEPTPPPGLLLFPSGPGGPSDPPTRLSLSRSDERRGTLSGAPAPPTRHDFSFDRVFPPGSGQDEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPGGDPQLEGLIPRALRHLFSVAQELSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGGECEIR---RAGPGSEELTVTNARYVPVSCEKEVDALLHLARQNRAVARTAQNERSSRSHSVFQLQISGEHSSRGLQCGAPLSLVDLAGSERLDPGLALGPGERERLRETQAINSSLSTLGLVIMALSNKES---HVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANRK--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LUU7-1", "uniprot_id": "Q1LUU7_DANRE", "id": "Q1LUU7-1", "name": "Kinesin-like protein", "aln": "-------------------------------------------------MNKENTSRLPVMSGKRAHTNSTDGEQQQPAQKKMR----KVEVEPSQ-RFRPAASVAPPRRPVAVKAPVKPLRPTGAATVAAAPARGDQRRPVAAVAKATAAVS----------RRPGWDLKGKVSDMEAKVQNYQSKVKTVN----QENECLKDSIAKVQRRTADIEQENNGLRRRLG----DCEKELVKLATVKDDLEHTTKE-------------RDGLQKDLSKLTEEHKVLEGLRDHLESELRNIQTQLAIQTSALGRCQDSLKESQE----------------------------LARNLEETVARQREELHLGEMERRKLHNTIQELKGNIRVFCRVRPLLTGNQSDILHIQLPPHDN-------KALTLAKMEESHTGRT--TDTQKSYNFSFDRVFGPRSSQSEVFEEISLLVQSALDGYNVCCFAYGQTGSGKTFTMEGGEQ--EELWGVIPRAVQQIFKSAKALSEQGWQYSFTASFVEIYNETLRDLLYKG-KPNKRPEHEIR---KVS--NNEITVTNLTYQKVNNEDEVHNLIMLANQNRSTARTCMNDHSSRSHSVFQLDIEGENTARDSKCKSMLCLVDLAGSERVQKSQSQG----ERFKEMTAINSSLTNLGIVIAALANKDS---FVPYRNSKLTYLLQNCLGGNSKTLMFANISPEEESFSESLNSLRFASKVNDCVIGTASANKK--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20480-1", "uniprot_id": "NCD_DROME", "id": "P20480-1", "name": "Protein claret segregational", "aln": "----MESRLPKPSGLKKPQMPIKTVLPTDRIRAGLGGGAAGAGAFNVNANQTYCGNLLPPLSRDLNNLPQVLERRGGGARAASPEPMKLGHRAKLRRSRSACDINELRGNKRTAAAPSLPSIPSKVSRLGGALTVSSQRLVRPAAPSSITATAVKRPPVTRPAPRAAGGAAAKKPAGTGAAASSGAAAAAPKRIAPYDFKARFHDLLEKHKVLKTKYEKQTEDMGELESMPQQLEETQNKLIETESSLKNTQSD-------------NECLQRQVKQHTAKIETITSTLGRTKEELSELQAIHEKVKTEHAALSTEVVHLRQRTE---------------------ELLRCNEQQAAELETCKEQLFQSNMERKELHNTVMDLRGNIRVFCRIRPPLESEENRMCCTWTYHDES--------------TVELQSIDAQAKSKMGQQIFSFDQVFHPLSSQSDIFEMVSPLIQSALDGYNICIFAYGQTGSGKTYTMDGVPES----VGVIPRTVDLLFDSIRGYRNLGWEYEIKATFLEIYNEVLYDLLSNE-----QKDMEIR---MAKNNKNDIYVSNITEETVLDPNHLRHLMHTAKMNRATASTAGNERSSRSHAVTKLELIGRHAEKQEISVGSINLVDLAGSESPKTS--------TRMTETKNINRSLSELTNVILALLQKQD---HIPYRNSKLTHLLMPSLGGNSKTLMFINVSPFQDCFQESVKSLRFAASVNSCKMTKAKRNRYLNNSVANSSTQSNNSGSFDK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17119-1", "uniprot_id": "KAR3_YEAST", "id": "P17119-1", "name": "Kinesin-like protein KAR3", "aln": "MESLPRTPTKGRSTQHLSTPSPKNDILAMNGHKRRNTTTPPPKHTLLKPQRTDIHRHSLASQSRISMSPNRELLKNYKGTANLIYGNQKSNSGVTSFYKENVNELNRTQAILFEKKATLDLLKDELTETKEKINAVNLKFETLREEKIKIEQQLNLKNNELISIKEEFLSKKQFMNEGHEIHLKQLAASNKKELKQMENEYKTKIEKLKFMKIKQFENERASLLDKIEEVRNKITMNPSTLQEMLNDVEQKHMLEKEEWLTEYQSQWKKDIELNNKHMQEIESIKKEIENTLKPELAEKKKLLTEKRNAYEAIKVKVKEKEEETTRLRDEVALKQKTNLETLEKIKELEEYIKDTELGMKELNEILIKEETVRRTLHNELQELRGNIRVYCRIRPALKNLENSDTSLINVNEFD------------DNSGVQSMEVTKIQNTAQVHEFKFDKIFDQQDTNVDVFKEVGQLVQSSLDGYNVCIFAYGQTGSGKTFTMLNPGD------GIIPSTISHIFNWINKLKTKGWDYKVNCEFIEIYNENIVDLLRSDNNNKEDTSIGLKHEIRHDQETKTTTITNVTSCKLESEEMVEIILKKANKLRSTASTASNEHSSRSHSIFIIHLSGSNAKTGAHSYGTLNLVDLAGSERINVSQVVG----DRLRETQNINKSLSCLGDVIHALGQPDSTKRHIPFRNSKLTYLLQYSLTGDSKTLMFVNISPSSSHINETLNSLRFASKVNSTRLVSRK------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . . : : . . : . . :. .: * : . : .. :* : : .: .: : : * : *: *** : :*:*****:**:** * . . : *.**::* . : ::*: :. *:**:**** :* ***********:** . *:** :: :*. . ** *.. . ::***** : *** . . :: .: ::* : . : :: *. *:.* *. *.:*****:: :.: * :: . . : ******** . . *: * ** **: * ** ** : :. .:*:******:** .* *.:* *** *:** .. ..*:::*****:.**. : . . ", "identical_positions": 116, "similar_positions": 124, "identity": "14.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000208-23", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K069-1", "uniprot_id": "A0A0G2K069_RAT", "id": "A0A0G2K069-1", "name": "Collagen alpha-2(XI) chain", "aln": "MERCSRCHRLLLLLPLVLGLSAAPGWAGAPSVDVLRALRFPSLPDGVRKSKGVCP------ADVAYRVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRSGLQAPLLTLYSAQGVQQLGLELGRPVRFLYEDQRGRPQASAQPIFRGLSLADGKWHHVAVAVKGQSVTLIVDCKKRVTRPLPRSVHPVLDTHGVVIFGAHVLDDEVFEGDVQELLIVPGVQAAYQSCGQKDLECER----------------EQRD-------------------------------------------------------GPQTQKPHRAQRSPKKEP-----------------------------------------------------------------------------------------------------------------------------------------------ARLHKPQNQEP----------------------------------------------------QQQPTESLYYDYEPPYYDVMTTETSPDYQYPTPGEEEGVLESSLLPSLEEEQTDLQVPPTADSFQAEEYGEGGTEPPA------------GFYDYTYGYGD------DYREETELGPALSAETDHTGAVAHGPRGLKGEKGEPAVLEPGMFVEGPPGPEGPAGLAGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGPPGPPGTSLMLPFRFGSSGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGEPGVKGDRGFDGLPGLPGEKGQRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPHGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPRGKPGLPGMPGSDGLPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPTGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPAGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGESGPMGERGHPGPPGPPGEQGLPGTAGKDGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPAGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPFGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGVQGEPGVKGPRGERGEKGESGQAGEAGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEAGPRGQDGAKGSQGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGTPGPEGRQGEKGAKGDPGAVGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPTGEQGEKGDRGLPGPQGSPGQKGETGIPGASGPIGPGGPPGLPGPSGPKGAKGATGPAGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSKLMQDE--EATPTGGAPGSPA--GLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTPRDDVT-----------------------QFSYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSG------VSQDG----PLKLRGANEDELSPETSPYVKEFRDGCQTQQ--GRTVLEVRTPVLEQLPVLDASFSDLGAPTRRGGVLLGPVCFMG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64739-2", "uniprot_id": "COBA2_MOUSE", "id": "Q64739-2", "name": "Collagen alpha-2(XI) chain", "aln": "MERCSRCHRLLLFLPLVLGLSAAPGWAGAPSVDVLRALRFPSLPDGVRRSKGVCP------GDVAYRVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVQQLGLELGRPVRFLYEDQRGRPQASAQPIFRGLSLADGKWHHVAVAVKGQSVTLIVDCKKRVTRPLPRSVHPVLDTHGVVIFGAHILDDEVFEGDVQELLVVPGVQAAYQSCGQKDLECER----------------EQRD-------------------------------------------------------GPQTQKPHRAQRSPKKEP-----------------------------------------------------------------------------------------------------------------------------------------------ARLHKPQSQEP----------------------------------------------------QKQPTESLYYDYEPPYYDVMTTGTAPDYQYPTPGEEEGVLESSPLPFLEEEQTDLQVSPTADSFQAEEYGEGGTDSPA------------GFYDYTYGYGD------DYREETELGPALSAETAHSGAVAHGPRGLKGEKGEPAVLEPGMFVEGPPGPEGPAGLAGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGPPGPPGTSLMLPFRFGSSGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGEPGMKGDRGFDGLPGLPGEKGQRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPHGPKGSLGPQGEPGPPGQQGTPGAQGLPGPQGAIGPHGEKGARGKPGLPGMPGSDGLPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPTGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPAGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGTAGESGPMGERGHSGPPGPPGEQGLPGTSGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPAGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDGGPMGPPGPPGPRGPAGPNGADGPQGSPGGVGNLGPPGEKGEPGESGSPGVQGEPGVKGPRGERGEKGESGQAGEAGPPGPKGPTGDNGPKGNPGPVGFPGDPGPPGEAGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGTPGPEGRQGEKGAKGDPGAVGAPGKTGPVGPAGLAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPTGEQGEKGDRGLPGPQGSPGQKGETGIPGASGPIGPGGPPGLPGPSGPKGAKGATGPAGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSKLIQDE--EAVPTGGAPGSPA--GLEEIFGSLDSLREEIEQMRRPAGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTPRDDVT-----------------------QFSYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSG------VSQDG----PLKLRGANEDELSPETSPYVKEFRDGCQTQQ--GRTVLEVRTPVLEQLPVLDASFADLGAPTRRGGVLLGPVCFMG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13942-1", "uniprot_id": "COBA2_HUMAN", "id": "P13942-1", "name": "Collagen alpha-2(XI) chain", "aln": "MERCSRCHRLLLLLPLVLGLSAAPGWAGAPPVDVLRALRFPSLPDGVRRAKGICP------ADVAYRVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPVRFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSARPVLDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEG----------------GQRE-------------------------------------------------------RPQNQQPHRAQRSPQQQP-----------------------------------------------------------------------------------------------------------------------------------------------SRLHRPQNQEP----------------------------------------------------QSQPTESLYYDYEPPYYDVMTTGTTPDYQDPTPGEEEEILESSLLPPLEEEQTDLQVPPTADRFQAEEYGEGGTDPPE------------GPYDYTYGYGD------DYREETELGPALSAETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPLGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQED--EAIPTGGAPGSPG--GLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTPRDDVT-----------------------QFSYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPCSG------AARDG----PLRLRGANEDELSPETSPYVKEFRDGCQTQQ--GRTVLEVRTPVLEQLPVLDASFSDLGAPPRRGGVLLGPVCFMG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T5W0-1", "uniprot_id": "A0AB32T5W0_DANRE", "id": "A0AB32T5W0-1", "name": "", "aln": "MDIRKKRRPWCMETSFVLLLCLS--MAQADPVDVLRVLQLPSLPEGVQKVPGFCTSRLSGTPDHAYRITKKAQISAPTKQLFSGRFPENFSIMTLVKAKAGLQAFLLSIYNEQGVQQLGLELGRSPIFLYEDQHRKPAPEDYPLFKGVNLADGKWHRIAISVQKKNITLILDCKNRITKTLPRSNNPVLDTKGITVFGARLLDEEVFQGEIQQLLIASNPQAAYDFCEHYSPDCDSPLPKVQSQDPNTYHFDEEQDDYEYPYYYEGTTSVPPSPSKPPSVPAETLTEQAGKANNGKVTKQKTAPAAKPAPAKPAKSKPTPAPKTAKSKPTAAQLLISKIKPTPASKLAAKPKATPAPKNDKKKTNDNGKVNNGQTKVNGNGNGKSNGNGKDTNGKAKAGSNGKPNNNGNGNGKKTNGDAKINGNGPKTVKTVTKVASAKKSETPATKTVTGKPKAQVKAQPTKSKTDKTKANASPAKPKDTKAKAASVTQKPAVFKPTPVPLPRPSKTILDVNNVKSMSRNFPPFDKAVVSATTIKKKPTNGYQQDVDPAYSEADHTPTETDYYYTVEEEAAPQPESDLTGYDESINQVDETVPVEEMDATKTGGEVASQTPEEPFTEEYITSDFGMKEYDYSYKDYNEPIIESKTEDTLGPALSAVTEEGGASVR---AIKGEKGEPAVLEPGMLIEGPPGPEGPAGLPGPSGPQGQPGSVGDPGERGPTGKAGLPGADGVPGPPGTSVMLPFRFGQSAGEKGPVASAQEAQAQAILSQARLALKGPSGPMGFTGRPGPLGTPGSPGFKGERGDPGAQGPRGPQGVSGPPGKAGRRGRAGADGARGMPGESGIKGDRGFDGLPGLPGDKGYRGQPGGMGPPGPHGEDGERGDDGDVGPRGLPGEPGPRGLLGPKGPSGLPGPPGVRGNDGPHGPKGNLGPQGEPGPPGQQGAPGTQGMPGPQGATGPPGEKGPTGKPGLPGMPGADGPPGHPGKEGPGGTKGNQGPNGPQGSIGYPGPRGLKGAQGIRGLKGHKGEKGEDGFPGIKGDFGVKGERGEVGVPGPRGEDGPEGPKGRVGPPGEIGPLGLLGEKGKLGVPGLPGYPGRQGIKGSLGFPGFPGTNGEKGTRGLIGKPGPRGQRGPTGPRGQRGPRGATGKSGAKGGSGSDGPPGPPGERGLTGPQGANGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKVGPPGPPGVVGPHGPSGETGQMGERGHPGPPGPPGEQGLSGSSGKEGTKGDPGPPGGPGKDGPPGLRGFPGERGLPGTPGSGGLKGNEGPAGPPGPAGSSGERGGAGTAGPVGPPGRPGPQGPPGTSGEKGVPGEKGPVGPAGRDGIQGPVGLPGPAGPPGISGEDGDKGEVGEPGQKGAKGSKGEHGPPGPPGPMGPVGQPGAAGADGETGPRGQQGQFGAKGDEGTRGFPGPPGPIGLQGLPGPGGEKGETGDVGPLGPPGPPGPRGPAGPNGADGPQGPPGGLGNPGPIGEKGEPGESGPPGVGGEPGKLGPRGERGEKGESGQPGTPGPPGGKGPTGDDGPKGNPGPVGFPGDPGPPGEVGPRGQDGAKGDRGEDGEQGEAGSPGPTGENGPPGPPGKRGPAGTRGPEGRQGEKGSKGDSGALGPPGKTGPVGPQGQPGKPGTEGLRGLPGTVGEQGSPGAAGPKGPPGPLGPPGLAGLRGDPGAKGEKGHPGMLGLIGPAGEQGEKGDRGMPGPQGSTGPKGETGISGGTGPLGPAGPAGMPGPRGVKGAKGASGGAGPKGEKGVQGPPGPPGPPGDVIQPLPIQIPKKSKRSIDASKILSEADAEAADTTGSEFLTGNEGMEEIFGSLNSLRQEIESMRFPLGTKESPGRTCQDLHLSQPDLKDGEYWIDPNQGCARDSFKVYCNFTAGGETCLYPSKAVENVKMNSWIKEKPGSLFSQFAKGNKFSYVDSVGEAVGVVQLGFLRLLSVQARQNLTYHCQRSVAWTDQTTDGGYKRALRLQGANDEEISYETSPYIKALIDGCSYRKGLDRTVLEVNTPQVEQLPLLDIRISDFGEDNQKFGFEVGPVCFLG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .: : : .:** *. : * * .*****.*::****:**:: *.*. * ***::: **:****:***.* **::**::*:*:::.**** **::*. ***:********. ****** :* . *:*:*:.*******::*::*: :.:***:***:*:*:.**** .*****:*: :***::**:***:*::*:* :... ****: * : . :*: ::: * ..:* * ::.:.:* : :*:. :. :.:**:. * :*.* :. * * .** .. * **. *. : :. *. : :: ** .::.* * :* *.* * : : * ******* * . ** .: .:**************::************ **.* **:**.*********.*:*****:** *******:*******...*:****.:**********.******:**.****:******** *****:*** ** *.********::**********************:.*:**************:** **:.*. * *** **********::********.***********.*:******** ***:****.**************:**:**:****** ** ****. **********:** ********* ********.****.:*******:**.:*******************:***:****:********.************.**.*: ** **:******************* ***********:.****:*** **.****:*********************** **.*** ********.****.********* **.********************.***********:*.:**:* ******.***********.*::**:**********.******.**************.*. ********:********.****.**:.**:*************::***********:**:****:**************::**********:*****:**.************:**************.*.** **:************ ************** ******** **:**********************.***:** ** **********.**: **** **************.* .**** ******:******************** **********.:***** *:.************** *******: *.***** **:***.**:*.********* * .****.:*******:**:** ***:* *****:*****.*****.**********::*****.**********:******.* *** **.*.:**:**.**.*:*** * ******:* .************* *****:********:***::**:*.*:::.: ** * *: .. *:*******:***:***.** * **::**.******:*.:*:* *****:*********:*:*:**********: * . * :****** *..****** *******.*:*:::* *. : ** .*:*:***::*:* *****:* : ***. :: .******.** :****:** ::*:* :: *. :*****:*", "identical_positions": 1217, "similar_positions": 333, "identity": "58.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000208-28", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y4X3-1", "uniprot_id": "CCL27_HUMAN", "id": "Q9Y4X3-1", "name": "C-C motif chemokine 27", "aln": "MK-GPPTFCSLLLLSLLLSPDPTAAFLLPPSTACCTQLYRKPLSDKLLRKVIQVELQEADGDCHLQAFVLHLAQRSICIHPQNPSLSQWFEHQERKLHGTLPKLNFGMLRKMG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IRX2-1", "uniprot_id": "A0A0R4IRX2_DANRE", "id": "A0A0R4IRX2-1", "name": "C-C motif chemokine", "aln": "MEFRSSCLLLLVCFTIIILTDNKAGAAIP---TCCLSVLRR-IPKRVLRSVRTYEVQDTSGHCEIKALILHFKGKKICAHPK---LERFLK----KMLKHKPKKP--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .. : *: ::::: .* .*. :* :** .: *: :..::**.* *:*::.*.*.::*::**: :.** **: *.:::: *: ** ", "identical_positions": 26, "similar_positions": 44, "identity": "23.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000208-8", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ABY2-1", "uniprot_id": "COPG2_RAT", "id": "D4ABY2-1", "name": "Coatomer subunit gamma-2", "aln": "-----MIKKFDKKDEESGSGSNPFQHLEKSAVLQEAR-IFNETPINPRRCLHILTKILYLLNQGEHFGTMEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKRWINEAQEAAS----------------SDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSG-LKSQFAYCMLIRIASRLLKES----EDGHESPLFDFIESCLRNKHEMVIYEAASAIIHLPNCTARELAP-----AVSVLQLFCSSPKPALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAIS-LCQKYPRKHSVMMTFLSNMLRD-DGGFEYKKAIVDCIISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPVPSKYIRFIFNRVVLENEAVRAAAVSALAKFGAQ--NESLLPSILVLLQRCMMDTDDEVRDRATFYLNVLQQRQMA---LNATYIFNGLTVSIPGMEKALHQYTLEPSE---KPFDMKSIP-------------------------------LAMAPVFEQKSEITLVTPK--PEKLAPSRQDIFQEQLAAIPEFVNLGPLFKSS-EPVQLTEAETEYFVRCVKHMFTDHIVFQFDCTNTLNDQLLEKVTVQMEPSD----SYEVLCCVPAPSLPYNQPGICYTLVRLPDEDPTA------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXK3-1", "uniprot_id": "COPG2_MOUSE", "id": "Q9QXK3-1", "name": "Coatomer subunit gamma-2", "aln": "-----MIKKFDKKDEESGSGSNPFQHLEKSAVLQEAR-IFNETPINPRRCLHILTKILYLLNQGEHFGTMEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAVERYMKQAIVDKVSSVASSALVSSLHMMKISYDVVKRWINEAQEAAS----------------SDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSG-LKSQFAYCMLIRIASRLLKES----EDGHESPLFDFIESCLRNKHEMVIYEAASAIIHLPNCTARELAP-----AVSVLQLFCSSPKPALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAISALCHKYPRKHSVMMTFLSNMLRD-DGGFEYKKAIVDCIISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPVPSKYIRFIFNRVVLENEAVRAAAVSALAKFGAQ--NESLLPSILVLLQRCMMDTDDEVRDRATFYLNVLQQRQMA---LNATYIFNGLTVSIPGMEKALHQYTLEPSE---KPFDMKSIP-------------------------------LAMAPVFEQKSEITLVTPK--PEKLAPSRQDIFQEQLAAIPEFMNLGPLFKSS-EPVQLTEAETEYFVRCVKHMFTDHIVFQFDCTNTLNDQLLEKVTVQMEPSD----SYEVLCCIPAPSLPYNQPGICYTLVRLPDEDPTAVAGTFSCTMKFTVRDCDPNTGVPD--EDGYDDEYVLEDLEVTVSDHIQKILKPNFAAAWEEVG--DAFEKEETFALSSTKTLEEAVNNIITFLGMQPCERSDKVPENKNSHSLYLAG--VYRGGYDLLVRSRLALADGVTMQVTVRSKERTPVDVILASVG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBF2-1", "uniprot_id": "COPG2_HUMAN", "id": "Q9UBF2-1", "name": "Coatomer subunit gamma-2", "aln": "-----MIKKFDKKDEESGSGSNPFQHLEKSAVLQEAR-IFNETPINPRRCLHILTKILYLLNQGEHFGTTEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKRWINEAQEAAS----------------SDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSG-LKSQFAYCMLIRIASRLLKET----EDGHESPLFDFIESCLRNKHEMVIYEAASAIIHLPNCTARELAP-----AVSVLQLFCSSPKPALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAISALCQKYPRKHSVMMTFLSNMLRD-DGGFEYKRAIVDCIISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPVPSKYIRFIFNRVVLENEAVRAAAVSALAKFGAQ--NESLLPSILVLLQRCMMDTDDEVRDRATFYLNVLQQRQMA---LNATYIFNGLTVSVPGMEKALHQYTLEPSE---KPFDMKSIP-------------------------------LAMAPVFEQKAEITLVATK--PEKLAPSRQDIFQEQLAAIPEFLNIGPLFKSS-EPVQLTEAETEYFVRCIKHMFTNHIVFQFDCTNTLNDQLLEKVTVQMEPSD----SYEVLSCIPAPSLPYNQPGICYTLVRLPDDDPTAVAGSFSCTMKFTVRDCDPNTGVPD--EDGYDDEYVLEDLEVTVSDHIQKVLKPNFAAAWEEVG--DTFEKEETFALSSTKTLEEAVNNIITFLGMQPCERSDKVPENKNSHSLYLAG--IFRGGYDLLVRSRLALADGVTMQVTVRSKERTPVDVILASVG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PUE4-1", "uniprot_id": "COPG2_DANRE", "id": "Q9PUE4-1", "name": "Coatomer subunit gamma-2", "aln": "-----MIKKFDKKDEESGSGSNPFQHLEKSAVLQEAR-IFNETPINPRRCLHILTKIIYLLNQGEHFGTTEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMANISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDTTMLQAIERYMKQAIVDKVPSVSSSALVSSLHMVKMSFDVVKRWVNEAQEAAS----------------SDNIMVQYHALGLLYHLRKNDRLAVTKMLNKFTKSG-LKSPFAYCMMIRIASKLLEET----EGGHDSPLFDFIESCLRNKHEMVVYEAASAIVHMPNCTARELAP-----AVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAISALCQKYPRKHSVMMNFLSNMLRD-DGGFEYKRAIVDCIISIIEENPESKETGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPTPSKYIRFIFNRVVLESEAVRAAAVSALAKFGAQ--NDDLLPSVLVLMQRCMMDSDDEVRDRATFYMNVLQQKQKA---LNAAYIFNGLSVSVLGLEKSLHQYTLEPSE---KPFDMKTVP-------------------------------LATAPITEHKTEIAPVATSKLPEKLAPSRQDIYQEQLSAIPEFQGLGPLFKSS-EPVQLTEAETEYVVRCIKHTFANHMIFQFDCTNTLNDQLLQKVLVQMEPSE----SYEVLHYVPAANLPYSQPGSCYSLVRLPEDDPTAVSCTFSCTMKYLVRDCDPNTGEPD--DDGYDDEYVLEDLEVTVADHIQKVLKPNFAAAWDEVG--DECEKEETFALATVRTLDEAVNNIVSFLGMQPCERSDKVPENKNSHVLFLAG--VFRGGHDVLVRARLALADGVTIQVTVRSTDDNVVDVILASVG-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9QZE5-1", "uniprot_id": "COPG1_MOUSE", "id": "Q9QZE5-1", "name": "Coatomer subunit gamma-1", "aln": "-----MLKKFDKKDEESGGGSNPLQHLEKSAVLQEAR-VFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQAVERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNEAQEAAS----------------SDNIMVQYHALGLLYHVRKNDRLAVSKMISKFTRHG-LKSPFAYCMMIRVASKQLEEE----DGSRDSPLFDFIESCLRNKHEMVVYEAASAIVNLPGCSAKELAP-----AVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRLMKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLRE-EGGFEYKRAIVDCIISIIEENSESKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPKTNNPSKYIRFIYNRVVLEHEEVRAGAVSALAKFGAQ--NEEMLPSILVLLKRCVMDDDNEVRDRATFYLNVLEQKQKA---LNAGYILNGLTVSIPGLEKALQQYTLEPSE---KPFDLKSVP-------------------------------LATTPMAEQRPESTATAAVKQPEKVAATRQEIFQEQLAAVPEFQGLGPLFKSSPEPVALTESETEYVIRCTKHTFSDHLVFQFDCTNTLNDQTLENVTVQMEPTE----AYEVLSYVPARSLPYNQPGTCYTLVALPTEDPTAVACTFSCVMKFTVKDCDPNTGEID--EEGYEDEYVLEDLEVTVADHIQKVMKVNFEAAWDEVG--DEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPENKNTHTLLLAG--VFRGGHDILVRSRLLLLDTVTMQVTARSSEELPVDIILASVG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4AEF8-1", "uniprot_id": "COPG1_RAT", "id": "Q4AEF8-1", "name": "Coatomer subunit gamma-1", "aln": "-----MLKKFDKKDEESGGGSNPLQHLEKSAVLQEAR-VFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQAVERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNEAQEAAS----------------SDNIMVQYHALGLLYHVRKNDRLAVSKMISKFTRHG-LKSPFAYCMMIRVASKQLEEE----DGSRDSPLFDFIESCLRNKHEMVVYEAASAIVNLPGCSAKELAP-----AVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRLMKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLRE-EGGFEYKRAIVDCIISIIEENSESKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPKTNNPSKYIRFIYNRVVLEHEEVRAGAVSALAKFGAQ--NEEMLPSILVLLKRCVMDDDNEVRDRATFYLNVLEQKQKA---LNAGYILNGLTVSIPGLEKALQQYTLEPSE---KPFDLKSVP-------------------------------LATTPMTEQRPESTSTAAVKQPEKVAATRQEIFQEQLAAVPEFQGLGPLFKSSPEPVALTESETEYVIRCTKHTFSDHLVFQFDCTNTLNDQTLENVTVQMEPTE----AYEVLSYVPVRSLPYNQPGTCYTLVALPKEDPTAVACTFSCVMKFTVKDCDPNTGEID--EEGYEDEYVLEDLEVTVADHIQKVMKVNFEAAWDEVG--DEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPENKNTHTLLLAG--VFRGGHDILVRSRLLLLDTVTMQVTARSSEELPVDIILASVG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y678-1", "uniprot_id": "COPG1_HUMAN", "id": "Q9Y678-1", "name": "Coatomer subunit gamma-1", "aln": "-----MLKKFDKKDEESGGGSNPFQHLEKSAVLQEAR-VFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNEAQEAAS----------------SDNIMVQYHALGLLYHVRKNDRLAVNKMISKVTRHG-LKSPFAYCMMIRVASKQLEEE----DGSRDSPLFDFIESCLRNKHEMVVYEAASAIVNLPGCSAKELAP-----AVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRLMKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLRE-EGGFEYKRAIVDCIISIIEENSESKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPKTTNPSKYIRFIYNRVVLEHEEVRAGAVSALAKFGAQ--NEEMLPSILVLLKRCVMDDDNEVRDRATFYLNVLEQKQKA---LNAGYILNGLTVSIPGLERALQQYTLEPSE---KPFDLKSVP-------------------------------LATAPMAEQRTESTPITAVKQPEKVAATRQEIFQEQLAAVPEFRGLGPLFKSSPEPVALTESETEYVIRCTKHTFTNHMVFQFDCTNTLNDQTLENVTVQMEPTE----AYEVLCYVPARSLPYNQPGTCYTLVALPKEDPTAVACTFSCMMKFTVKDCDPTTGETD--DEGYEDEYVLEDLEVTVADHIQKVMKLNFEAAWDEVG--DEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPDNKNTHTLLLAG--VFRGGHDILVRSRLLLLDTVTMQVTARSLEELPVDIILASVG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8I0G5-1", "uniprot_id": "COPG_DROME", "id": "Q8I0G5-1", "name": "Coatomer subunit gamma", "aln": "MNYFSLTSHKKHRGHPSAGPSNAYQNLEKTSVLQETR-TFNETPVNPRKCIHILTKILYLINQGEQLVAREATDCFFAMTKLFQSKDVVLRRMVYLGIKELSSIAEDVIIVTSSLTKDMTGKEDLYRAAAIRALCSITDNTMLQAVERYMKQCIVDKNAAVSCAALVSSLRLANTAGDVVKRWANEAQEALN----------------SDNIMVQYHALGLLYHIRKSDRLAVSKLVNKLTRGS-LKSPYAVCMLIRIACKLIEEEDIPSEELSDSPLFTFIESCLRHKSEMVIYEAAHAIVNLKNTNPRMLSP-----AFSILQLFCSSPKATLRFAAVRTLNKVAMTHPAAVTTCNLDLEGLITDSNRSVATLAITTLLKTGAESSVERLMKQISTFVAEISDEFKVVVVQAICALCTKYPRKHTVLMNFLSGMLRE-EGGLEYKTSIVDTIITIIEENADAKESGLSHLCEFIEDCEHVSLAVRILHLLGKEGPFAATPSKYIRFIYNRVILESPIVRAAAVTAMAQFGAS--CPALLSNILVLLGRCQMDPDDEVRDRATYYLSILNSERPE---LYKNYIIERENCSLALLEKSLVEHLNGDVD---TRFDISIVP-------------------------------KAAIVKPVIANDVMLVTSS-APRPPKITREEESAARLAQLPGIQVLGPIHRST-APIQLTESETEYTVQCIKHIFGQHVVFQFDCLNTLSDQILENVRVELTLPE----GFTTRAVIPCPKLPYNDLQTTFVIVEFPPDAANSIA-TFGATLRFVVKDCDPNTGEPES-EEGYDDEYMLEDLELTVADQIQKTRKNNFQVSWDAADSEEWLQAEDTFVLSAVTTLQDAVNTIVKILGLGAANLSENVPEGTHLHTLLCSG--TFRGGAEILVRAKLALSEGVTLNLTVRSTDQDVAELITAAIG-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32074-1", "uniprot_id": "COPG_YEAST", "id": "P32074-1", "name": "Coatomer subunit gamma", "aln": "-----MSAHTYKKFENSTSG----DLPDKMTIYQDCMNTFNESPVNSKRCRLLISRLLRLLAQGETFPQNEATALFFSISKLFQHQNDPLRQAVYLAIKELSGISEDVLMATSSIMKDVQNGSDLIKPDAIRSLTYVLDESTAFSAERLLKSAVVSRHPSISSAALCTSYHLLPISEVTIRRFTNETQEAVLDLKQFPNQHGNSEYYPNSTYISQYHALGLLYQLKKTDKMALLKLVRHFSENNSMKNQLAKVELVKIVNDLIYRD-----PQLFSQFRPLLSDWLSNKFESVQLETAKLITSFATRNSRLVAPELYAAAISALQSLLTVPRVSSRFAALRILNRISMVSPEKIVVCNPELESLINDSNRNISTYAITTLLKTGTSKNISSLISTITNFIHDVSDDFKIIIIDAVRTLSLNFPQEWKSILNFLIDVLKNSEGGFKFKNSIVEALIDIVSFVPQSKELALENLCDFIEDCEFNEILVRILHLLGKEGPSAPNPSLYVRHIYNRVVLENSIIRSAAVVALSKFALTKNDPTLYESIISLLKRIANDKDDEVRDRATIALEFIDSARNKDDVIAQNLIESKYFYDIPSLESKLSSYISSNTDSFATAFDVNQVRKFTEDEMKAINLKRKQEQIFNQKSETTLDTTPEAESVPEKRADANSFAGPNLDDHQEDLLATKYADELLSIEQIKPFGQLVNSS-RAISLTEPEAEFVVRGVKHLFKDNVVLQFNITNTLTDIALDNVSVVCTPEISDEAELEELFTLQVDRLLPSEEAACYVAFKKLD---EIVMEGFLNNLTFTTKEINPDTNEPFDGDEGFQDEYEIDSIFLNAGDYVKSSFTGNFSATFDELP----CEEVAVFNIQEDLSIQEVVDKIILNSSCLPVESTQFAPSDSNSHTLKLFGKSALTGSKVALQIKMIKSSKGLALKVHGKGEDSLLCSDLVNGLMQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: . * . : :* :: *: ***:*:*.::* :::::: *: *** : *** **::::*** :: **: ** ***:: *:***::.***: **: . .* : *:*:* : * : : ** :*..:*.: .:::.:** :* :: : .::*: **:*** ... : ******:**:::*.*::*: *:: :.:. . :*. * ::::. : . * : ::.. * :* * * *:* * : ..: ::* *.* ** : : *: : *:**:* **:::* * :..** :**.*:.****.::* *********:...:. *:. *:.*: ::**:**:::::*: *. ::*:: ::.** :*:: :**:::* :**: :* *:. .::** .* :**:******. : .:******:*** : ** *:*.*:***:** :*:.** *:::*. : .:: *: * * *:******* :..::. : : * . .: :* * .: : . **:. : : : .* : : :* : .*: .: ***.*:*: :: ** * :::::**: ***.* *::* * : * .: : . ", "identical_positions": 202, "similar_positions": 247, "identity": "21.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000209-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55005-1", "uniprot_id": "ROBO1_RAT", "id": "O55005-1", "name": "Roundabout homolog 1", "aln": "---MKWKHLPLLVMISLLTLSKKH---------LLLAQLIPDPEDLERGNDNGTPA-----------PTSDNDDNSLGYTGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYICVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDER--------ITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESKVADVTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTFGWRKDD--GELPKSRYEIRDD-HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG--DLTVTNVQRSDVG-YYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTLTLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLESG--VLQIRYAKLGDTGRYTCTASTPSGEATWSAYIEVQEFGVP-VQPPRPTDPNLIPSAPSKPEVTDVSKNTVTLLWQPNL--NSG-ATPTSYIIEAFSHASGSSWQTVAENVKTETFAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQD--------VPPTTQGVDHKQVQRELGN-VVLHLHNPTILSSSSVEVHWT--VDQQSQYIQGYKILYRPSGASHGE------------------------------------------------------------SEWLVFEVRTPTKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEERPSAPPRSVTVSKNDGNGTAILVTWQPP-PEDTQNGMVQEYKVWCLGNE-----TRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGPGVKSEPQFIQLDSHGNPVSP--EDQVSLAQQIS--DVVKQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLSSTYAGIR--KVPSFTFTPTVTYQRGGEAVSSGGRPGLLNISEPATQPWLADTWPNTGNSHNDCSINCCTASNGNSDSNLTTYSRPADCIANYNNQLDNKQTNLMLPESTVYGDVDLSNKINEMKTFNSPNLKDGRFVNPS---GQPTPYATTQLIQANLINN-MNNGGGDSS--------EKHWKP----PGQQKQEVAPIQYNIMEQNKLNKD-YRANDTILPTIPYNHSYDQNTGGSYNSSDRGSSTSGSQGHKKGARTPKAPKQGGMNWADLLPPPPAHPPPHSNSEEYSMSVDESYDQEMPCPVPPARMYLQQDELEEEEA----ERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEDLGHMPHPPDRRRQPVSPPPPPRPISPPHTYGYISGPLVSDMD----TDAPEEEEDEADMEVAKMQTR-------------RLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEEDNISSGRS-SVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQ-------DAAGRRHFHASQCPRPTSPVSTDSNMSAAVIQKARPTKKQKHQP----GHLRREAYTDDLPPPPVPPPAIK-SPSVQSKAQLEA-RPIMGPKLASIEARADRSSDRKGGSYKGREALDGRQVTDLRTSPGDPREAQEQPNEGKARGTKTAKRDLPPAKTHLIPEDILPYCRPTFPTSNNPR---DPSSSSSMSSRGSGSRQREQANVGRRNMAEMQVLGGFERGDENNEELEETES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89026-1", "uniprot_id": "ROBO1_MOUSE", "id": "O89026-1", "name": "Roundabout homolog 1", "aln": "-----------------MIAEPAH---------FYLFGLIC------------------------------------LCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYICVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDER--------ITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDD--GELPKSRYEIRDD-HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG--DLTITNVQRSDVG-YYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTLILSCVATGSPAPTILWRKDGVLVSTQDSRIKQLESG--VLQIRYAKLGDTGRYTCTASTPSGEATWSAYIEVQEFGVP-VQPPRPTDPNLIPSAPSKPEVTDVSKNTVTLSWQPNL--NSG-ATPTSYIIEAFSHASGSSWQTAAENVKTETFAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQD--------VPPTSQGVDHKQVQRELGN-VVLHLHNPTILSSSSVEVHWT--VDQQSQYIQGYKILYRPSGASHGE------------------------------------------------------------SEWLVFEVRTPTKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPRSVTVSKNDGNGTAILVTWQPP-PEDTQNGMVQEYKVWCLGNE-----TKYHINKTVDGSTFSVVIPSLVPGIRYSVEVAASTGAGPGVKSEPQFIQLDSHGNPVSP--EDQVSLAQQIS--DVVRQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLTSTYAGIR--KVPSFTFTPTVTYQRGGEAVSSGGRPGLLNISEPATQPWLADTWPNTGNNHNDCSINCCTAGNGNSDSNLTTYSRPADCIANYNNQLDNKQTNLMLPESTVYGDVDLSNKINEMKTFNSPNLKDGRFVNPS---GQPTPYATTQLIQANLSNN-MNNGAGDSS--------EKHWKP----PGQQKPEVAPIQYNIMEQNKLNKD-YRANDTIPPTIPYNQSYDQNTGGSYNSSDRGSSTSGSQGHKKGARTPKAPKQGGMNWADLLPPPPAHPPPHSNSEEYNMSVDESYDQEMPCPVPPAPMYLQQDELQEEED----ERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEDLGHMPHPPDRRRQPVSPPPPPRPISPPHTYGYISGPLVSDMD----TDAPEEEEDEADMEVAKMQTR-------------RLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEEDNISSGRS-SVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQ-------DAAGRRHFHASQCPRPTSPVSTDSNMSAVVIQKARPAKKQKHQP----GHLRREAYADDLPPPPVPPPAIK-SPTVQSKAQLEV-RPVMVPKLASIEARTDRSSDRKGGSYKGREALDGRQVTDLRTNPSDPREAQEQPNDGKGRGTRQPKRDLPPAKTHLGQEDILPYCRPTFPTSNNPR---DPSSSSSMSSRGSGSRQREQANVGRRNMAEMQVLGGFERGDENNEELEETES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6N7-1", "uniprot_id": "ROBO1_HUMAN", "id": "Q9Y6N7-1", "name": "Roundabout homolog 1", "aln": "---MKWKHVPFLVMISLLSLSPNH---------LFLAQLIPDPEDVERGNDHGTPI-----------PTSDNDDNSLGYTGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDER--------ITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDD--GELPKSRYEIRDD-HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG--DLTITNVQRSDVG-YYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG--VLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVP-VQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNL--NSG-ATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQD--------VLPTSQGVDHKQVQRELGN-AVLHLHNPTVLSSSSIEVHWT--VDQQSQYIQGYKILYRPSGANHGE------------------------------------------------------------SDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPP-PEDTQNGMVQEYKVWCLGNE-----TRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEPQFIQLDAHGNPVSP--EDQVSLAQQIS--DVVKQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLTSTYAGIR--KVPSFTFTPTVTYQRGGEAVSSGGRPGLLNISEPAAQPWLADTWPNTGNNHNDCSISCCTAGNGNSDSNLTTYSRPADCIANYNNQLDNKQTNLMLPESTVYGDVDLSNKINEMKTFNSPNLKDGRFVNPS---GQPTPYATTQLIQSNLSNN-MNNGSGDSG--------EKHWKP----LGQQKQEVAPVQYNIVEQNKLNKD-YRANDTVPPTIPYNQSYDQNTGGSYNSSDRGSSTSGSQGHKKGARTPKVPKQGGMNWADLLPPPPAHPPPHSNSEEYNISVDESYDQEMPCPVPPARMYLQQDELEEEED----ERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEETGHMQHQPDRRRQPVSPPPPPRPISPPHTYGYISGPLVSDMD----TDAPEEEEDEADMEVAKMQTR-------------RLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEEDNISSGRS-SVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQ-------DAAGRRHFHASQCPRPTSPVSTDSNMSAAVMQKTRPAKKLKHQP----GHLRRETYTDDLPPPPVPPPAIK-SPTAQSKTQLEV-RPVVVPKLPSMDARTDRSSDRKGSSYKGREVLDGRQVVDMRTNPGDPREAQEQQNDGKGRGNKAAKRDLPPAKTHLIQEDILPYCRPTFPTSNNPR---DPSSSSSMSSRGSGSRQREQANVGRRNIAEMQVLGGYERGEDNNEELEETES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T813-1", "uniprot_id": "A0AB32T813_DANRE", "id": "A0AB32T813-1", "name": "", "aln": "---MEFIPLVVSILAMLVMMGVQHGGTPG---VPRHASLRNQPNQWCKRPHGSFLVGAHHRPTQQRHHNSKKHKCFQDFQRSRLRQEDYAPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTVEWYKDGERVETDRDNPRSHRMLLPTGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSHNASLEVAILRDDFRQNPVDVMVAAGEPAVMECQPPRGHPEPTISWKKDGVNIDDRDER--------ITIRGGKLMITNTRKTDAGKYVCVGTNMMGERESEIAELTVLERPSFLRKPSSQSVLVDQSVEFRCEAQGDPVPTIRWRKED--GELPKGRYEIWED-HTLKLKRLTSGDAGTYTCQAENMMGKTEASATLTVHVPPVFVVRPRNQVAGMGRTVTFQCEATGSPQPAIFWQKEGSQNLLFSSQPPPPSSRFSVSQTG--DLTITAVERSDGG-YYSCQALNIAGSVITKALLEVTDVISDRPPPIVRQGPTNQTVAVDGTVVLSCQATGTPIPTILWRKDGVLVSTHDSRLKQLDTG--ALQIRYAKLGDTGMYTCTASTPSGEASWKAYLEVQEFGAP-VQPGRPTDPNLIPSAPSKPDVTDVSRTSVSLSWKPNL--NAG-ATPTSYVIEAFSHAAGSSWQTLADHVKTESFVLKGLKPSAVYLFLVRAANAYGLSDPSPISDAVKTQD--------VPPTSQGVEHGQIQRELGD-VVIHLHNPTILSSSSVRVQWT--VEQQSQYIQGYKVMYRPSPEGAPQR-----------------------------------------------------------VDWAMFEVGAPGEHSAVVTQLKKGITYEFKVRPFFNEFQGTDSDIKVGKTLEEAPSAAPRGVTVTGSGDNGTAVLVAWQPP-PEEEQNGVVQEYKIWCLGNE-----SRYHINRTVDGSTHSVLIPGLVAGVTYRLEVAAGTGAGPGVKSDPTSFQLDSSGRVLPPPLDDDNTISQQIS--DVVRQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLSSSYAGIR--KVPSFTFTPTVAYQRGGEAVSSAGRPGLLNIGEPATQPWLADTWPNSCSNHNDCTINCCTGSNGNSDSNLATYSRPADCIANYSNQMDNKATNLLAPDTGLYSDVDLSNKINEMKTFNSPNLKDGRFMGPG---GQPTPYATTQLIQSSLANNNMNSSSGGSGGGSADFNEKQSWKSSQGTPQKQADINTPLQYNVMEQNKLNKDHYRGEGPISVTIPYNQAQDVLTGETYSSSDRGSSTSGSQGQKKGGRTTKQAKQNPMNWTELLPPPPVNPPP---CQEYTLVMDDSYDTDLQCPLPPSRMYLQPDELEEEEDEVELERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEEMHPMLQDNPD-------LHERRRLLVSPPPPPRPLSPPHTYGYISSPLGLDTDGLEEEDDDEEEGDETDAEVARVHQHHMMHPHQQHLPQQRALLRGLEQTPASSTCDLESSVTGSMINGWGSASEEDNASSGRSSAVSSSDGSFFTDADFAQAVAAAAEYAGLRVAKHPGKGHHQLPVSGAARKYQNLPAGHRPGSPVSTDSNVSAAPGQR-RPLKRQKQHPAAQTGYQRREAYTEDLPPPPIPPPAMLKSPTHPAKTIPEGPRGAMSPRSSSADGKDRRTGAG------GPRVRDG---SDTRTSSSERRDGQDVQR-GQRTGKNSKQDEAVKSRQHPGSEDILPYSRPSFPAVHSPRGERDPSSSSSLSSRGSGGRRRGEGPPGARRNPADIGLNTIGAFQTGGDELEMVES", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PC46-1", "uniprot_id": "M9PC46_DROME", "id": "M9PC46-1", "name": "", "aln": "MHLCEMRGMPLRLQPQCLTNESEIQIKIKSKIKNKTASEIKRRHRNNRDFHGERLKIMPVDRSRRAVFPLLLLLAGLNGLTQVGALKGENPRIIEHPMDTTVPKNDPFTFNCQAEGNPTPTIQWFKDGRELKTDTG---SHRIMLPAGGLFFLKVIHSRR-ESDAGTYWCEAKNEFGVARSRNATLQVAFLRDEFRLEPANTRVAQGEVALMECGAPRGSPEPQISWRKNGQTLNLVGNKRI------RIVDGGNLAIQEARQSDDGRYQCVVKNVVGTRESATAFLKVHVRPFLIRGPQNQTAVVGSSVVFQCRIGGDPLPDVLWRRTASGGNMPLRRVHVLED-RSLKLDDVTLEDMGEYTCEADNAVGGITATGILTVHAPPKFVIRPKNQLVEIGDEVLFECQANGHPRPTLYWSVEGNSSLLLPGYR-DGRMEVTLTPEGRSVLSIARFAREDSGKVVTCNALNAVGSVSSRTVVSVDTQF-ELPPPIIEQGPVNQTLPVKSIVVLPCRTLGTPVPQVSWYLDGIPIDVQEHERRNLSDAGALTISDLQRHEDEGLYTCVASNRNGKSSWSGYLRLDTPTNPNIKFFRAPELSTYPGPPGKPQMVEKGENSVTLSWTRSN--KVGGSSLVGYVIEMFGKNETDGWVAVGTRVQNTTFTQTGLLPGVNYFFLIRAENSHGLSLPSPMSEPITVG---------TRYFNSGLDLSEARASLLSGDVVELSNASVVDSTSMKLTWQ--IIN-GKYVEGFYVYARQLPNPIVNNPAPVTSNTNPLLGSTSTSASASASASALISTKPNIAAAGKRDGETNQSGGGAPTPLNTKYRMLTILN-GGGASSCTITGLVQYTLYEFFIVPFYKSVEGKPSNSRIARTLEDVPSEAPYGMEALLLN--SSAVFLKWKAP-ELKDRHGVLLNYHVIVRGIDTAHNFSRILTNVTIDAASPTLVLANLTEGVMYTVGVAAGNNAGVGPYCVPATLRLDPITKRLDPFINQRYPINQDHVN-DVLTQPWFIILLGAILAVLMLSFGAMVFVKRKHMMMKQSALNTMRGNHTS-DVLKMPSLSARNGNGYWLDSSTGGMVWRPSPGGDSLEMQKDHIADYAPVCGAPGSPAGGGTSSG----GSGGAGSGASGGDDIHGGHGSERNQQRYVGEYSNIPTDYAEVSSFGKAPSEYGRHGN-----ASPAPYATSSILSP----------------------------------------------HQQQQQQQPRYQQRPVPGYGLQRPMHPHYQQQQHQQQQAQQTHQQHQALQQHQQ---LPPSNIYQQMSTTSEIYPTNTGPSRSVYSEQY-----------YYPKDKQRHIHITENKLSNCH------------------TYEAAPGAKQSSPISSQF------------------------------------------------------------------------------------------------ASVRRQQLPPNCSIGRESARFK----------VLNTDQGKNQ-QNLLDLDGSSMCYNGLADSGCGGSPSPMAMLMSHEDE----------------HALYHTADGDLDDMERLYVKVDEQQPPQQQQQLIP--------------------------------------------LVPQHPAEGHLQSWRNQS-----------------TRSSRKNGQECIKEPSELIYAPGSVASERSLLSNSGSGTSSQPAGHNVXPLLPGSSLG---QSQSKSQSQSQSQSDLQSQEQLYAREVRELLAWCERFNNGGVENFE------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPZ7-1", "uniprot_id": "Q9VPZ7_DROME", "id": "Q9VPZ7-1", "name": "", "aln": "-------------------------------------------------------------MDLRFVFIVFLLKW-------THAQGSHPPRIVEHPIDTTVPRHEPATLNCKAEGSPTPTIQWYKDGVPLKILPG---SHRITLPAGGLFFLKVVNSRR-ETDAGIYWCEAKNELGVARSRNATLQVAVLRDEFRLEPQNTRIAQGDTALLECAAPRGIPEPTVTWKKGGQKLDLEGSKRV------RIVDGGNLAIQDARQTDEGQYQCIAKNPVGVRESSLATLKVHVKPYIIRGPHDQTVLEGASVTFPCRVGGDPMPDVLWLRTASGGNMPLDRVSVLED-RSLRLERVTIADEGEYSCEADNVVGAITAMGTLTVYAPPKFIQRPASKSVELGADTSFECRAIGNPKPTIFWTIKNNSTLIFPGAPPLDRFHSLNTEEGHSILTLTRFQRTDKDLVILCNAMNEVASITSRVQLSLDSQE-DRPPPIIISGPVNQTLPIKSLATLQCKAIGLPSPTISWYRDGIP--VQPSSKLNITTSGDLIISDLDRQQDQGLYTCVASSRAGKSTWSGFLRIELPTNPNIKFYRAPEQTKCPSAPGQPKILNATASALTIVWPTSD--KAGASSFLGYSVEMYCTNQSRTWIPIASRLSEPIFTVESLTQGAAYMFIVRAENSLGFSPPSPISEPITAGKLVGVRDGSESTGTSQLLLSDVETLLQANDVVELLEANASDSTTARLSWD--IDS-GQYIEGFYLYARELHS--------------------------------------------------------------SEYKMVTLLNKGQGLSSCTVPGLAKASTYEFFLVPFYKSIVGKPSNSRRMRTLEDVPEAPPYGMEAIQFN--RTSVFLKWLPPQPNRTRNGILTSYNVVVKGLD-VHNTTRIFKNMTIDAAAPTLLLANLTTGVTYYIAVAAATRVGVGPFSKPAVLRIDARTQSLDTGY-TRYPISRDIAD-DFLTQTWFIVLLGSIIAIIVFLLGALVLFKR-YQFIKQTSLGSLHGNHAIGTVRKFPTLPLNGGGAVGAGGSNSTAAAGQSGHGLWIDPTSG-VWRQAAGGGNPGGVGSCTTKEQ----LPGYAQATAQQGQQPTLLPDYERLSPLNMPDYAEVACSTFKSPTHGAPPMGGGGGGQSASLYDSCGAYATTNVVAN----------------------------------------------VKLYQN---RYATKPNQSSGSNNNNHQGNDYQSTGMYSAPPSAHYGCLEPKQQQ---QQQQPNLMTTSTASTAILTNS-------------------------PAKVKKINITENKMDQLEG----------------KSERTNPFNQQQQLLLASN------------------------------------------------------------------------------------------------ALKQGLGAYANTTLAAQMASGG----------GAGTLRRQRQPKTLYKSENNILGKSGLRQNTMNASVG-------------------------------APSNGQMDFLT--------GGPPSEGGDFSG--------------------------------------------LGLCNSTNQLLNDWASSA-----------------SIAAPGDYHFGSKQPSKQHLYVKAKDGTWSAVSSDAYQSFKHQQQH--HPFLAGSGDN---TKSLASVNSLAGDSKFLS-------------------SFGSSANV-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W213-1", "uniprot_id": "Q9W213_DROME", "id": "Q9W213-1", "name": "", "aln": "-----------------------------------MHPMHPENHAIARSTSTTNNPSRSRSSRMWLLPAWLLLVLVASNGLPAVRGQYQSPRIIEHPTDLVVKKNEPATLNCKVEGKPEPTIEWFKDGEPVSTNEK--KSHRVQFKDGALFFYRTMQGKK-EQDGGEYWCVAKNRVGQAVSRHASLQIAVLRDDFRVEPKDTRVAKGETALLECGPPKGIPEPTLIWIKDGVPLDDLKAMSFGASSRVRIVDGGNLLISNVEPIDEGNYKCIAQNLVGTRESSYAKLIVQVKPYFMKEPKDQVMLYGQTATFHCSVGGDPPPKVLWKKEE--GNIPVSRARILHDEKSLEISNITPTDEGTYVCEAHNNVGQISARASLIVHAPPNFTKRPSNKKVGLNGVVQLPCMASGNPPPSVFWTKEGVSTLMFPNSS---HGRQHVAADG--TLQITDVRQEDEG-YYVCSAFSVVDSSTVRVFLQVSSLD-ERPPPIIQIGPANQTLPKGSVATLPCRATGNPSPRIKWFHDGHAVQAGNRYSIIQGSS---LRVDDLQLSDSGTYTCTASGERGETSWAATLTVEKPGST--SLHRAADPSTYPAPPGTPKVLNVSRTSISLRWAKSQEKPGAVGPIIGYTVEYFSPDLQTGWIVAAQRVGDTQVTISGLTPGTSYVFLVRAENTQGISVPSGLSNTIKTIE--------ADFDAASANDLSAARTLLTGKSVELIDASAINASAVRLEWMLHVSADEKYVEGLRIHYKDASVPS--------------------------------------------------------------AQYHSITVMDASAESFVVGNLKKYTKYEFFLTPFFETIEGQPSNSKTALTYEDVPSAPPDNIQIGMYN--QTAGWVRWTPP-PSQHHNGNLYGYKIEVSAGN----TMKVLANMTLNATTTSVLLNNLTTGAVYSVRLNSFTKAGDGPYSKPISLFMDPTHHVHPPRAHPSGTHDGRHEGQDLTYHNNGNIPPGDINPTTHKKTTDYLSGPWLMVLVCIVLLVLVISAAISMVYFKRKHQMTKELGHLSVVSDNEITALNINSKESLWIDHHRGWRTADTD----------------------------KDSGLSESKLLSHVNSSQSNYNNSDGGTDYAEVDTRNLTTFYNCRKSPDN-----PTPYATTMIIGTS-----------------------------------------------------------SSETCTKTTSISADKDSGTHSPYSDAFAGQVPAVPVVKSN----YLQYPVEPINWSEFLPPPPEHPPP------------------------SSTYGYAQGSPESSRK----------------SSKSAGSGISTNQSILNAS------------------------------------------------------------------------------------------------IHSSSSGGFSAWGVSPQYAVACPPENVYSNPLSAVAGGTQNRYQITPTNQHPPQLPAYFATTGPGGAVPPNHLPFATQRH--------------AASEYQAGLNAARCAQSRACNSCDALATPSPMQPPPP---------------------------------------------VPVPEGWYQPVHPNSHP-----------------MHPTSSNHQIYQCSSECSDHSRSSQSHKRQLQLEEHGSSAKQRGGHHRRRAPVVQPCMESENENMLAEYEQRQYTSDCCNSSREGDTCSCSEGSCLYAEAGEPAPRQMTAKNT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:*** * * : :* *:**:.** * **::*:*.* :. ***: : *.*** : ::.:: . * * * * *:* .* * *::*:*::*.***:** :* :. :* *: *::** .*:* *** : * *.* :: : **:* * .. * *.* *: * :* *** * : * :* ::: * . . :. * * *** * . * : *::* * : .* ::*.: :* * * * * *.* :* * . * * ** * :* .: . :. . : * * * * *:::* :. ..*::. . : * * :: . : * . *.::. . * :. :.: : ***:: **.***:. . * * : * * * : * ** . . : * * *** ** *:::* . : :: . . *..: . *..*. *.: : .:::: * . . .. .* :* : * . .: . .* .. *.*::** *: *:* ** :*:.:.. . * :.* :.. .::: .: * : :*::* : : : * .: * : **: **:: . * *: : * *: *. .* .: . :: : * .* ::* : *:: . : : * *::.:: :::: *. * * : : : . .* * . * : :*. . . . *. : * : : . . . . . : . : : . . .***: :: : . :.: . :. . .. .. . : : . . . : . : : : .: . * . : . . . .. : . : . ", "identical_positions": 194, "similar_positions": 295, "identity": "10.59%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000209-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2I4-3", "uniprot_id": "ROBO3_MOUSE", "id": "Q9Z2I4-3", "name": "Roundabout homolog 3", "aln": "MLRYLLKTLLQMNLFADSLARDISNSSELLFGFNSSLAALNPSLLPPGDPS-LNGSRVGPEDAMPRIVEQPPDLVVSRGEPATLPCRAEGRPRPNIEWYKNGARVATAREDPRAHRLLLPSGALFFPRIVHGRRSRPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPAVMECVPPKGHPEPLVTWKKGKIKLKEEEGR--------ITIRGGKLMMSHTFKSDAGMYMCVASNMAGERESGAAELVVLERPSFLRRPINQVVLADAPVNFLCEVQGDPQPNLHWRKDD--GELPAGRYEIRSDH-SLWIDQVSSEDEGTYTCVAENSVGRAEASGSLSVHV----PPQFVTKPQNQTVAPGANVSFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPMGRLLVSPRGQLNITEVKIG---DGGYYVCQAVSVAGSILAKALLEIKGASIDGLPPIILQGPANQTLVLGSSVWLPCRVIGNPQPNIQWKKDERWLQGDDSQFNLMDNGTLHIASIQEM-DMGFYSCVAKSSIGEATWNSWLRKQEDW--GASPGPATGPSNPPGPPSQPIVTEVTANSITLTWKPNP--QSG-ATATSYVIEAFSQAAGNTWRTVADGVQLETYTISGLQPNTIYLFLVRAVGAWGLSEPSPVSEPVQTQDSSLSRP-AEDPWKGQRGLAEVA--------VRMQEPTVLGPRTLQVSWTVDG--PVQLVQGFRVSWRIAGLDQGSWTMLDLQSPHKQSTVLRGLPPGAQIQIKVQVQGQEGLGAESPFVTRSIPEEAPSGPPQGVAVALGGDRNSS-VTVSWEPP-LPSQRNGVITEYQIWCLGNES----RFHLNRSAAGWARSVTFSGLLPGQIYRALVAAATSAGVGVASAPVLVQLPFP---PAAEPG---PEVSEGLAERLAKVLR---------KPAFLAGSSAACGALLLGFCAALYRRQKQRKELSHYTASFAYTPAVSFPHSEGLSGSSSRP-PMGLGPAAYPWLADSWPHPPRSPSAQEPRGSCCPSNPDPDDRYYNEAGISLYLAQTARGANASGEGPVYSTIDPVGEELQTFHGGFPQHSS-------------------GDPSTWS--------QYAPPEWSEGDSGARGGQGKLLGKPVQMPSLSWPEALPPPPPSCELS-CPEGPEEELKG--SSDLEEWCPPVPEKSHLVGSSSSGACMVAPAPRDTPSPTSSYGQQSTATLTPSPPDPPQPPTDIPHLHQMPR------------RVPLGPSSPLSVSQPALSSHDGRPVG----LGAGPVLSYHASPSPVPSTASSAPGRTRQVTGEMTPPLHGHRARIRKKP-KALPYRREHSPGDLPPPPLPPPEEETSWPLGLRAAGSMSSLERERSGERRVVQAVPLGAQPLGAQRGPHPDAALLGCAAEEAWLPYGRPSFLSHGQGTSTCSTAGSNSSRGSNSSRGSRGSRGPGRSRSRSRSQSQSQRPGRNRREEPR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AJI9-1", "uniprot_id": "A0A8I6AJI9_RAT", "id": "A0A8I6AJI9-1", "name": "Roundabout homolog 3", "aln": "MLRYLLKTLLQMNLFADSLAGDITNSSELLFGFNSSLAALNPSLLPPGDPS-LNGSRVGPEDAMPRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATAREDPRAHRLLLPSGALFFPRIVHGRRSRPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPAVMECVPPKGHPEPLVTWKKGNTKLKEEEGR--------ITIRGGKLMMSHTFKSDAGMYMCVASNMAGERESGAAELVVLERPSFLRRPINQVVLADAPVNFLCEVQGDPQPNLRWRKDD--GELPTGRYEIRSDH-SLWIEQVSAEDEGTYTCVAENSVGRAEASGSLSVHV----PPQFVTKPQNQTAAPGENVSFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPMGRLLVSPRGQLNITEVKIG---DGGYYVCQAVSVAGSILAKALLEIKGASIDGLPPIILQGPANQTLVLGSSVWLPCRVIGNPQPNVQWKKDETWLQGDNSQFNLMDNGTLYIASVQEM-DMGFYSCVAKSSIGEATWNSWLRKREHW--GASPGPATEPGNPPGPPSQPIVTEVTTNSITLTWKPNP--QSG-ARATSYVIEAFSQAAGNTWRTVADGVQLETHTVSGLQPNTIYLFLVRAVGAWGLSEPSPVSEPVQTQDSSLSRP-VEDPWKGQQGLAEVA--------VRMQEPIVLGPRTLQVSWTVEG--PGQLVQGFRVSWRIAGLDQGSWTALDVQSPHKQSTVLRGLPPGSQIQIKVQVQGQEGLGAESPSVTRSIPEEAPSGPPQGVAVALGGDRNSS-ITVSWEPP-LPSQQNGVITEYQIWCLGNES----RFHLNRSAAGWARSVMFRGLLPGLLYRAIVAAATSAGVGVASAPVLVQLPFP---PVAEPG---PEVSEGLAERLSRVLR---------KPAFLAGSSAACGALLLGLCAALYRRQKQRKELSHYTASFAYTPAVSFPHSEGLSGSSSRP-PMGLGPAAYPWLADSWPHPSRSPSAQEPRGSCCPSNPDPDDRYYNEAGISLYLAQTARGANAPGEGPVYSTIDPVGEELQTFHGGFPQHSS-------------------GDPSTWS--------QYAPPEWSEGDSGARGGKGKLLGKPVQMPSLSWPEALPPPPPSCELS-CPEGPEEELKG--SSDLEEWCPPMPEKKHLIDSRSSGACMVAPARGETPSPTSSYGQQSTATLTPSPPDPPQPPSDIPHLHQMPR------------RVPLGPSSPLSVSQPALSSHDGRPVG----LGAGPIVSYHPSPSPVPSTASSAPGRTRQVTGEMTPPLHGHRARIRKKT-KALPHRREHSPGDLPPPPLPPPEEETSWPLGLRAAGSMSSLEREHSGERRVAQAVPLGAQPPGAQRGPHPDAALLGCAAEEAWLPYGRPSFLSHGQGTSTCSTAGSNSSRGSNSSRGSRGSRGPGRSRSRS--QSQSQRPGRNRRQEPR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96MS0-1", "uniprot_id": "ROBO3_HUMAN", "id": "Q96MS0-1", "name": "Roundabout homolog 3", "aln": "MLRYLLKTLLQMNLFADSLAGDISNSSELLLGFNSSLAALNHTLLPPGDPS-LNGSRVGPEDAMPRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGALFFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEEGR--------ITIRGGKLMMSHTLKSDAGMYVCVASNMAGERESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKED--GELPTGRYEIRSDH-SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHV----PPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRG---DAGYYVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANGTLYIANVQEM-DMGFYSCVAKSSTGEATWSGWLKMREDW--GVSPDPPTEPSSPPGAPSQPVVTEITKNSITLTWKPNP--QTG-AAVTSYVIEAFSPAAGNTWRTVADGVQLETHTVSGLQPNTIYLFLVRAVGAWGLSEPSPVSEPVRTQDSSPSRP-VEDPWRGQQGLAEVA--------VRLQEPIVLGPRTLQVSWTVDG--PVQLVQGFRVSWRVAGPEGGSWTMLDLQSPSQQSTVLRGLPPGTQIQIKVQAQGQEGLGAESLSVTRSIPEEAPSGPPQGVAVALGGDGNSS-ITVSWEPP-LPSQQNGVITEYQIWCLGNES----RFHLNRSAAGWARSAMLRGLVPGLLYRTLVAAATSAGVGVPSAPVLVQLPSP---PDLEPG---LEVGAGLAVRLARVLR---------EPAFLAGSGAACGALLLGLCAALYWRRKQRKELSHYTASFAYTPAVSFPHSEGLSGASSRP-PMGLGPAPYSWLADSWPHPSRSPSAQEPRGSCCPSNPDPDDRYYNEAGISLYLAQTARGTAAPGEGPVYSTIDPAGEELQTFHGGFPQHPS-------------------GDLGPWS--------QYAPPEWSQGDSGAKGGKVKLLGKPVQMPSLNWPEALPPPPPSCELS-CLEGPEEELEG--SSEPEEWCPPMPERSHLTEPSSSGGCLVTPSRRETPSPTPSYGQQSTATLTPSPPDPPQPPTDMPHLHQMPR------------RVPLGPSSPLSVSQPMLGIREARPAG----LGAGPAASPHLSPSPAPSTASSAPGRTWQGNGEMTPPLQGPRARFRKKP-KALPYRRENSPGDLPPPPLPPPEEEASWALELRAAGSMSSLERERSGERKAVQAVPLAAQ-----RVLHPD--------EEAWLPYSRPSFLSRGQGTSTCSTAGSNSSRGSSSSRGS---RGPGRSRSRSQSRSQSQRPGQKRREEPR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BJU1-1", "uniprot_id": "A0A8M2BJU1_DANRE", "id": "A0A8M2BJU1-1", "name": "", "aln": "MLRYLIKTLLQMNLFTDTIR-DATNGTDLFFNISS-IPSFNSSLLDWANFTGLNGSRPRLEDAAPRIVEHPSDLIVSKGEPATLNCKAEGRPTPMVEWYKDGERVETDREDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGVYVCVARNYLGEAVSRNASLEVAILRDDFRQTPSDVVVAAGEPAVMECIPPRGHPEPTISWKRNNVKVNDKDER--------ITIRGGKLMISNTRKSDAGMYVCVGTNMVGEKDSDPAELVVFERPMFVRRPVNQVVLADDTVDFQCEVQGDPAPTIRWKKEE--GELPRGRFEIRADN-SLRLTQVKAEDEGSYTCLSENSVGKAEASGSLQVHVGPSLPPQIVVRPRDQISAQGRTVTFLCGTKGNPPPAVFWQKEGSQVLLFPSQPPSQSGRFSVSLSGELTITDVHSE---DSGYYICQAISVAGSILTKALLEVESTPSDRIPPIIRQGPANQTLAPGTTAQLQCHVMGNPLPSIQWERDGQRILGIDERISLMENGTLQITALQET-DSGAYTCVASSLSGETSWSGVLTVKESG--GLSASPVSEPYQLPGPPQKPVVTDVTRNSVTLTWQPNA--HEGGAAVTSYIIEAFSQSAGSTWQTVADFVKLEKHTVTGLSPNTIYLFIVRAVNAYGLSDPSPISEPVRTQDVSPTGQ-GVDHRQVQRELGEMS--------VQLHEPVLLTASSVKISWNVDR--QSQYIQGYRLLYRPVG---GSWSQQEVKGATERSAVIANLLKGTEYEIKIRPYFNEFQGLDSRSQTLRTPEEVPSAPPRAVNVATVKLSNSSSISVSWQPP-PTDMQNGVIQEYKVWCLGNDSQ--TRYNINQTVDGSVLSTVLKGLLPGVLYQVEVAAVTSAGVGKHSQPVSVLIKLPAEQPTVTGGGSESEENVSLAEQITDVVK---------QPAFIAGIGGACWVILMGFSVWIYCRRKKRKELSHYTASFAYTPAVGFPHGE-SSGLNGRPGMLGANMGNYPWLADSWPTTNLVHNGKDSVN-CCTSKHETPERYYNEAGISNYLNQNEKYSADSNEGPIYSTIDPTSEDLRSFTAQYSQHTTPYASTPIMPFTNQAPCSPEQDGSHWMTQPGTSNAQYAQPDRSKTEN-VKQPKQKLMGKPVKTPSLNWMDALPPPPISGDLEQCDEEDDNELIQDMGSDEEEWCPPLPERSYLMDGMVEDG-PVPPPRGEASSPTTSYSHQSTATLTPSPRDD-GHFHDIPRLHQLEQPHMTRRLPCGPVPVPRAPSPPLTQSNPNLSANQECPDNTVPHRSAHKRDLSQGAAQSVENISNTTPGRARPSADHTSS---GQKSKVKKKASKSAQYRRDILQGDLPPPPEPPPEDQDNCAHVGGFECGQTSLERAGSSNSSMERREQSTPN--------RKNSAHRRIDADDDLIPYNKPNFLSRGQMSSNCSTTGSSSSRGSTGSRGQ--------------------GTGRKRNDEMR-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W213-1", "uniprot_id": "Q9W213_DROME", "id": "Q9W213-1", "name": "", "aln": "--------MHPMHPENHAIARSTSTTNNPSRSRSSRMWLLPAWLLLVLVAS-NGLPAVRGQYQSPRIIEHPTDLVVKKNEPATLNCKVEGKPEPTIEWFKDGEPVSTN--EKKSHRVQFKDGALFFYRTMQGKKEQ-DGGEYWCVAKNRVGQAVSRHASLQIAVLRDDFRVEPKDTRVAKGETALLECGPPKGIPEPTLIWIKDGVPLDDLKAMSFGASSRVRIVDGGNLLISNVEPIDEGNYKCIAQNLVGTRESSYAKLIVQVKPYFMKEPKDQVMLYGQTATFHCSVGGDPPPKVLWKKEE--GNIPVSRARILHDEKSLEISNITPTDEGTYVCEAHNNVGQISARASLIVHA----PPNFTKRPSNKKVGLNGVVQLPCMASGNPPPSVFWTKEGVSTLMFPNSS---HGRQHVAADGTLQITDVRQE---DEGYYVCSAFSVVDSSTVRVFLQVSSLD-ERPPPIIQIGPANQTLPKGSVATLPCRATGNPSPRIKWFHDGHAVQAGN-RYSIIQGSSLRVDDLQLS-DSGTYTCTASGERGETSWAATLTVEKPG--STSLHRAADPSTYPAPPGTPKVLNVSRTSISLRWAKSQEKPGAVGPIIGYTVEYFSPDLQTGWIVAAQRVGDTQVTISGLTPGTSYVFLVRAENTQGISVPSGLSNTIKTIEADFDAASANDLSAARTLLTGKS--------VELIDASAINASAVRLEWMLHVSADEKYVEGLRIHYKDASVPSAQYHSITVMDASAESFVVGNLKKYTKYEFFLTPFFETIEGQPSNSKTALTYEDVPSAPPDNIQIGMYNQTAGW---VRWTPP-PSQHHNGNLYGYKIEVSAGNT---MKVLANMTLNATTTSVLLNNLTTGAVYSVRLNSFTKAGDGPYSKPISLFMDPTHHVHPPRAHPSGTHDGRHEGQDLTYHNNGNIPPGDINPTTHKKTTDYLSGPWLMVLVCIVLLVLVISAAISMVYFKRKHQMTKELGHLSVVSDNEITALNINSKESLWIDHHRGWRTADTDKDSGLSESKLLSHVNSSQSNYNNSDGGTDYAEVDTRNLTTFYNCRKSPDNPTPYATTMIIGTSSSETCT-----------------------------------KTTSISADKDSGTHSPYSDAFAGQVPAVPVVKSNYLQYPVEPINWSEFLPPPPEHPPP---SSTYGYAQGSPESSRKSSKSAGSGISTNQSILNASIHSSSSGGFSAWGVSPQYAVACPPENVYSNPLSAVAGG----------TQNRYQITPTNQHPPQLPAYFATTGPG---GAVPPNHLPFATQRHAASEYQAGLNAARCAQSRACNSCDALATPSPMQPPPPVPVPEGWYQPVHPNSHPMHPTSSNHQIYQCSSECSDHSRSSQSHKRQLQLEEHGSSAK-------QRGGHHRRRAPVVQPCMESENENMLAEYEQRQYTSDCCNSSREGDTCSCSE-----------GSCLYAEAGEPAPRQMTAKNT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPZ7-1", "uniprot_id": "Q9VPZ7_DROME", "id": "Q9VPZ7-1", "name": "", "aln": "---------------------------------MDLRFVFIVFLLKWTHAQ---------GSHPPRIVEHPIDTTVPRHEPATLNCKAEGSPTPTIQWYKDG---VPLKILPGSHRITLPAGGLFFLKVVNSRRET-DAGIYWCEAKNELGVARSRNATLQVAVLRDEFRLEPQNTRIAQGDTALLECAAPRGIPEPTVTWKKGGQKLDLEGSK------RVRIVDGGNLAIQDARQTDEGQYQCIAKNPVGVRESSLATLKVHVKPYIIRGPHDQTVLEGASVTFPCRVGGDPMPDVLWLRTASGGNMPLDRVSVLEDR-SLRLERVTIADEGEYSCEADNVVGAITAMGTLTVYA----PPKFIQRPASKSVELGADTSFECRAIGNPKPTIFWTIKNNSTLIFPGAPPLDRFHSLNTEEGHSILTLTRFQRTDKDLVILCNAMNEVASITSRVQLSLDSQE-DRPPPIIISGPVNQTLPIKSLATLQCKAIGLPSPTISWYRDGIPVQPSS-KLNITTSGDLIISDLDRQQDQGLYTCVASSRAGKSTWSGFLRIELPTNPNIKFYRAPEQTKCPSAPGQPKILNATASALTIVWPTSD--KAGASSFLGYSVEMYCTNQSRTWIPIASRLSEPIFTVESLTQGAAYMFIVRAENSLGFSPPSPISEPITAGKLVGVRDGSESTGTSQLLLSDVETLLQANDVVELLEANASDSTTARLSWDIDS---GQYIEGFYLYARELHSSEYKMVTLLNKGQGLSSCTVPGLAKASTYEFFLVPFYKSIVGKPSNSRRMRTLEDVPEAPPYGMEAIQFNRTSVF---LKWLPPQPNRTRNGILTSYNVVVKGLDVHNTTRIFKNMTIDAAAPTLLLANLTTGVTYYIAVAAATRVGVGPFSKPAVLRIDAR--TQSLDTGYTRYPISRDIADDFLTQTW---------FIVLLGSIIAIIVFLLGALVLFKRYQFIKQTSLGSLHGNHAIGTVRKFPTLPLNGGGAVGAGGSNSTAAAGQSGHGLWIDP----TSGVWRQAAGGGNPGGVGSCTTKEQLPGYAQATAQQGQQPTLLPDYERLSPLNMPDYAEVACSTFKSP----------------------------------THGAPPMGGGGGGQSASLYDSCGAYATTNVVANVKLYQNR--------YATKPNQSSGS--NNNNHQGNDYQSTGMYSAPPSAHYGCLEPKQQQQQQQPNLMTTSTASTAILTNSPAKVKKINITENKMDQLE-------------GKSERTNPFNQQQQLLLASNALKQG------LGAYANTTLAAQMASGGGAGTLRRQRQPKTLYKSENNILGKSGLRQNTMNASVGAPSNGQMDFLTGGPPSEGGDFSGLGLCNSTNQLLNDWASSASIAAPGDYHFGSK-------QPSKQHLYVKAKDGTWSAVSSDAYQSFKHQQQHHPFLAGSGDNTKSLASVN--------------SLAGDSKFLSSFGSSANV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ** ***:*:* * * : ***** *:.** * * ::*:*:* . :**: : *.*** : ::.:: * * * * *:* :* * **:*:*::*:***:** * :. :* *:.*::** .*:* *** : * :. :. : **:* :... * * * *:. * .* ::* * : * :* ::: * :*.:* . .. * * * *** * : * : *::* .* : *. ** : .:. *** * * :.* ** * .:* *:. **:: :* .: . . : * : *** *::** :. ..*:**. . : : * :* .: . :*.*.. . * :. *.:.. : **:* **.**** : . * *:. * * * : * :* : . : . .. * : :: * * *:*.*.. *:::* . * . . . . *..* * : : : .:::: * . . . .* :* :. * *. : *: .* .: *:*:*** .: *:* ** :*:.: : . . : * *.: :. . : ::.* :. : ::* : : . . * .: .* : :: : : * * *:.*..** : : * ** :** : *:: . : : * : . . : : .* .* * : : * .* * * * : : . . : . * : :. . . : .. . . . * . . .. . * : . . . . . . . . . : . : .. . . : . :: : .. . . * . * : . . : . . . . .: : . . . ... . .. : . . ", "identical_positions": 195, "similar_positions": 305, "identity": "12.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000210-10", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3KR92-1", "uniprot_id": "TPST1_RAT", "id": "Q3KR92-1", "name": "Protein-tyrosine sulfotransferase 1", "aln": "-MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPARLENPKATVRTGLDIKANKTFTYHKNMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEVIVKHGEPAPYLCNKDPFALKSLTYLARLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLHIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKILENTRRVHKGEFQLPDFLKEKPQTEQVE--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70281-1", "uniprot_id": "TPST1_MOUSE", "id": "O70281-1", "name": "Protein-tyrosine sulfotransferase 1", "aln": "-MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPARLENPKATVRAGLDIKANKTFTYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEVIVKHGEPAPYLCNKDPFALKSLTYLARLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLHIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKILENTRRVYKGEFQLPDFLKEKPQTEQVE--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60507-1", "uniprot_id": "TPST1_HUMAN", "id": "O60507-1", "name": "Protein-tyrosine sulfotransferase 1", "aln": "-MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPVKLESTRTTVRTGLDLKANKTFAYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLSRLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKIIENTRRVYKGEFQLPDFLKEKPQTEQVE--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PTE6-1", "uniprot_id": "TPST1_DANRE", "id": "Q9PTE6-1", "name": "Protein-tyrosine sulfotransferase 1", "aln": "-MIGKLKQNLLVACLVISSVTVFYLCRHAMDCHHRIEERSQPL-LSSLHATLRTGQNLST--PFIYNKDMPLIFIGGVPRSGTTLMRAMLDAHPDVRCGEETRVIPRILAMKQMWSRSGREKMRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPANYLCNKDPFALKSLTYLAKIFPHAKFILMVRDGRASVHSMISRKVTIAGFDLSSYRDCLTKWNRAIETMYTQCLEA-ADKCLPVHYEQLVLHPEKWMRTLLRFLNIPWNDAVLHHEELIGKAGGVSLSKVERSTDQVIKPVNVEALSKWVGKIPLDVQRDMAVIAPMLARLGYDPHANPPNYGRPDPLVLDNTRRLQK--------SPEKPNPS-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYB7-1", "uniprot_id": "TPST_DROME", "id": "Q9VYB7-1", "name": "Protein-tyrosine sulfotransferase", "aln": "MRLPYRNKKVTLWVLFGIIVITMFLFKFTELRPTCLFKVDAANELSSQMVRVEKYLTDDNQRVYSYNREMPLIFIGGVPRSGTTLMRAMLDAHPDVRCGQETRVIPRILQLRSHWLKSEKESLRLQEAGITKEVMNSAIAQFCLEIIAKHGEPAPRLCNKDPLTLKMGSYVIELFPNAKFLFMVRDGRATVHSIISRKVTITGFDLSSYRQCMQKWNHAIEVMHEQCRDIGKDRCMMVYYEQLVLHPEEWMRKILKFLDVPWNDAVLHHEEFINKPNGVPLSKVERSSDQVIKPVNLEAMSKWVGQIPGDVVRDMADIAPMLSVLGYDPYANPPDYGKPDAWVQDNTSKLKANRMLWESKAKQVLQMSSSEDDNTNTIINNSNNKDNNNNQYTINKIIPEQHSRQRQHVQQQHLQQQQQQHLQQQQHQRQQQQQQREEESESEREAEPDREQQLLHQKPKDVITIKQLPLAGSNNNNINNNINNNNNNNNIMEDPMADT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::: : *. * .::* :.: : : . . *.. . :. . : *:::**************************:***:********* ::. * :* :*.:**:***:*.**::**: * **:*.****** ******::** :*: .:**:***::*******:***:*******:****.***:*: ***:***.*: ** : .:*: *:*********.***.:*:**.:***.:******:*.*..**.*******:********: *:*****:** ** :*** *****: *****:****:**:**. : :** :: : : . ", "identical_positions": 192, "similar_positions": 97, "identity": "38.48%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000210-13", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQ18-1", "uniprot_id": "D3ZQ18_RAT", "id": "D3ZQ18-1", "name": "F-box only protein 50", "aln": "MACPAPPPPVNLDPRNHDPVVQTLGMEKIPDRDALSGRMEAEGSQNSEELPPHPQSPPPPPSPR---------SPTSPETPELPQPNAPTEFEARQLLVEEWGPVSGKLELPPSISWKLLFLERPLYRNLLNSPNPEGINIYQPAPPTG------PTRKP--LKELGNFRGWYITTENLQGPLS---------------WTVKEQCVNLLAKKLWEELLDDEQPDITIMDWFEDSRLDQCVYELHVWLLAADRRTVIAQHHVAPRTNGRGPPGRWVQVSHVFRQYGPGVRFVHFQHKTKNRMEPGGLRRTRVTDSSVSVQLRE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3X9C2-1", "uniprot_id": "FBX50_MOUSE", "id": "G3X9C2-1", "name": "F-box only protein 50", "aln": "-------------------------MEKTQDRDTLSGRMEAEGSLNSEELPPHPQSPPPPPSPR---------SPTSPVTPELPQPNAPTEVEARQLLVEEWGPLSGKLELPPRISWQLLFLERPLYRNLLSSPNPEGINIYQPAPPTG------PTRKP--LKELGNFRGWYITTQNLQGPLS---------------WTVKEQCVNLLAKKLWEELLDDEQPDITIMDWFEDSRLDQCVYELHVWLLAADRRTVIAQHHVAPRTNGRGPPGRWIQVSHVFRQYGPGVRFVYFQHKAKNRMEPGGLRRTRVTDSSVSVQLRE----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZVX7-1", "uniprot_id": "FBX50_HUMAN", "id": "Q6ZVX7-1", "name": "F-box only protein 50", "aln": "-------------------------MEEVREGHALGGGMEADGPASLQELPPSPRSPSPPPSPPPLPSPPSLPSPAAPEAPELPEPAQPSEAHARQLLLEEWGPLSGGLELPQRLTWKLLLLRRPLYRNLLRSPNPEGINIYEPAPPTG------PTQRP--LETLGNFRGWYIRTEKLQQNQS---------------WTVKQQCVDLLAEGLWEELLDDEQPAITVMDWFEDSRLDACVYELHVWLLAADRRTVIAQHHVAPRTSGRGPPGRWVQVSHVFRHYGPGVRFIHFLHKAKNRMEPGGLRRTRVTDSSVSVQLRE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q568V3-1", "uniprot_id": "FBX50_DANRE", "id": "Q568V3-1", "name": "F-box only protein 50", "aln": "-----------------------------------------------------------------------------------------MATDWKQKCDSEWQLGAHGVPMPDTVDWKSVFETKPFERNLLQNPSPYGVNHTVPPPEPHRSGIPPPSDRPPQLEPEGNFSGWKTNTEVLPYDTSGIPPGVVICQLPQHRWFTLEQCVDLKAAGLWDQLLDDFQPEIVIEDWYEESQLHKCIYQLDVKLLGADGETVIKQHTYNPEEDLECYSHTWKKVSHVFSKYAPGVRYIHFLHRLKNQFMVEFFN-TKVTDSSVIVKASKPSVK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* .** : : :* : *: :: :*: **** .*.* *:* *.* . *: :* *: *** ** *: * * * . :***:* * **::**** ** *.: **:*:*:*. *:*:*.* **.** .*** ** *. . . . * :***** :*.****:::* *: **:: :. *:****** *: : ", "identical_positions": 84, "similar_positions": 55, "identity": "25.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000210-17", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q15717-1", "uniprot_id": "ELAV1_HUMAN", "id": "Q15717-1", "name": "ELAV-like protein 1", "aln": "--------------------------------------MSNGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNKSHK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QTX4-1", "uniprot_id": "A0A2R8QTX4_DANRE", "id": "A0A2R8QTX4-1", "name": "ELAV-like protein", "aln": "MAVRRGHIRYLKVCEVQNQGNDRDSHKGASSIKQEVYDMPNGYEDPMGDEPSD--AKTNLIINYLPQNMSQEELRSLFSSIGEVESAKLIRDKMAGHSLGYGFVNYVNPSDAERAINTLNGLRLQSKTIKVSYARPSSDGIKDANLYISGLPKTMTQKNVEDMFTQYGRIINSRILVDQASGLSRGVAFIRFDKRSEAEEAIKDLNGSKPSGASEPITVKFAANPNQSKNSQLLSQLYHTQSRRFGGPVHHQPQRFRFSPMSVDHS--VSSMNVASSSSSGWCIFVYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTSKCKGFGFVTMTNYEEAAMAISSLNGYRLGDKVLQVSFKSSKSHK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.***** *.:: . .:****:*******:*:*********************:*************...****************************: ************:*****:*****:::*******:****::*********************..:** **.*:**************.** *******: :**********.********.*** :*.:**...:*******:*********************************.********************:**********:******:.****", "identical_positions": 267, "similar_positions": 46, "identity": "73.35%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000210-20", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04762-1", "uniprot_id": "CATA_RAT", "id": "P04762-1", "name": "Catalase", "aln": "MADSRDPASDQMKQWKEQRAPQKPDVLTTGGGNPIG-DKLNIMTAGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDAMLFPSFIHSQKRNPQTHL---KDPDMVWDFWSLCPE--SLHQVTFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLPVEEAGRLAQEDPDYGLRDLFNAIASGNYPSWTFYIQVMTFKEAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNRNPANYFAEVEQMAFDPS-NMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVN------CPYR------------ARVAN-YQRDGPMCMHDNQGGAPNYYPN-----------------------------SFSAPEQQG--SALEHHSQCSADVKRFNSAN-EDNVTQVRTFYTKVLNE-EERKRLCENIANHLKDAQ-LFIQRKAVKNFTDVHPDYGARVQALLDQYNS-QKPKNAIHTYVQAGSHIAAKGKANL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24270-1", "uniprot_id": "CATA_MOUSE", "id": "P24270-1", "name": "Catalase", "aln": "MSDSRDPASDQMKQWKEQRASQRPDVLTTGGGNPIG-DKLNIMTAGSRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVTGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDAILFPSFIHSQKRNPQTHL---KDPDMVWDFWSLRPE--SLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNADGEAVYCKFHYKTDQGIKNLPVGEAGRLAQEDPDYGLRDLFNAIANGNYPSWTFYIQVMTFKEAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNKNPVNYFAEVEQMAFDPS-NMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVN------CPYR------------ARVAN-YQRDGPMCMHDNQGGAPNYYPN-----------------------------SFSAPEQQR--SALEHSVQCAVDVKRFNSAN-EDNVTQVRTFYTKVLNE-EERKRLCENIAGHLKDAQ-LFIQKKAVKNFTDVHPDYGARIQALLDKYNA-EKPKNAIHTYTQAGSHMAAKGKANL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04040-1", "uniprot_id": "CATA_HUMAN", "id": "P04040-1", "name": "Catalase", "aln": "MADSRDPASDQMQHWKEQRAAQKADVLTTGAGNPVG-DKLNVITVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITKYSKAKVFEHIGKKTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPILFPSFIHSQKRNPQTHL---KDPDMVWDFWSLRPE--SLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLSQEDPDYGIRDLFNAIATGKYPSWTFYIQVMTFNQAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNRNPVNYFAEVEQIAFDPS-NMPPGIEASPDKMLQGRLFAYPDTHRHRLGPNYLHIPVN------CPYR------------ARVAN-YQRDGPMCMQDNQGGAPNYYPN-----------------------------SFGAPEQQP--SALEHSIQYSGEVRRFNTAN-DDNVTQVRAFYVNVLNE-EQRKRLCENIAGHLKDAQ-IFIQKKAVKNFTEVHPDYGSHIQALLDKYNA-EKPKNAIHTFVQSGSHLAAREKANL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PT92-1", "uniprot_id": "CATA_DANRE", "id": "Q9PT92-1", "name": "Catalase", "aln": "MADDREKSTDQMKLWKEGRGSQRPDVLTTGAGVPIG-DKLNAMTAGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHVGKTTPIVVRFSTVAGEAGSPDTVRDPRGFAVKFYTDEGNWDLTGNNTPTFFIRDTLLSPSFIHSQKRNPQTHL---KDPDMVWDFWSLRPE--SLHQVSFLFSDRGIPDGYRHMNGYGSHTFKLVNAQGQPVYCKFHYKTNQGIKNIPVEEADRLAATDPDYSIRDLYNAIANGNFPSWTFYIQVMTFEQAENWKWNPFDLTKVWSHKEFPLIPVGRFVLNRNPVNYFAEVEQLAFDPS-NMPPGIEPSPDKMLQGRLFSYPDTHRHRLGANYLQLPVN------CPYR------------TRVAN-YQRDGPMCMHDNQGGAPNYYPN-----------------------------SFSAPDVQP--RFLESKCKVSPDVARYNSAD-DDNVTQVRTFFTQVLNE-AERERLCQNMAGHLKGAQ-LFIQKRMVQNLMAVHSDYGNRVQALLDKHNA-EGKKNTVHVYSRGGASAVAAASKM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P17336-1", "uniprot_id": "CATA_DROME", "id": "P17336-1", "name": "Catalase", "aln": "MAG-RDAASNQLIDYKNSQ-TVSPGAITTGNGAPIG-IKDASQTVGPRGPILLQDVNFLDEMSHFDRERIPERVVHAKGAGAFGYFEVTHDITQYCAAKIFDKVKKRTPLAVRFSTVGGESGSADTARDPRGFAVKFYTEDGVWDLVGNNTPVFFIRDPILFPSFIHTQKRNPQTHL---KDPDMFWDFLTLRPE--SAHQVCILFSDRGTPDGYCHMNGYGSHTFKLINAKGEPIYAKFHFKTDQGIKNLDVKTADQLASTDPDYSIRDLYNRIKTCKFPSWTMYIQVMTYEQAKKFKYNPFDVTKVWSQKEYPLIPVGKMVLDRNPKNYFAEVEQIAFSPA-HLVPGVEPSPDKMLHGRLFSYSDTHRHRLGPNYLQIPVN------CPYK------------VKIEN-FQRDGAMNVTDNQDGAPNYFPN-----------------------------SFNGPQECPRARALSSCCPVTGDVYRYSSGDTEDNFGQVTDFWVHVLDK-CAKKRLVQNIAGHLSNAS-QFLQERAVKNFTQVHADFGRMLTEELNLAKS-SKF----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLI6-1", "uniprot_id": "Q9VLI6_DROME", "id": "Q9VLI6-1", "name": "", "aln": "MCS-RDTASNQLIDYKNND-SEVQREITTSSGTPVG-VKDAIQTVGPRGPALLQDFQFLDEVMHFDSERIPERVAYAKGAGAFGYFECTHDISKFCAASIFDKVRKRTAVAMRFSVACGEQGSADTVREQRGFAVKFYTDDGIWDIVGCNMPVHYVRDPMLFPSLVHAQKRNPQTHL---KDPDMFWDFMTLRPE--TLHALLMYFSDRGTPDGYRHLHGYGVHTYRMINASGETQYVRFHFKTDQGIKNLDARRCEELMSHDPDYAIRDLYNSIKKGNYPSWSMYIQVMLNEEAKKCRFNPFDVTKVWPQKDFPLLPVGKIVLDRNPTNYFTEVEQLAFSPA-HMVPGIEPSPDKMLQGRLFAYGDSQRHRLGVNYMQIPVN------CPYR------------VNVRN-FQRDGAMTVTDNQNGAPNYFPN-----------------------------SFCGPRESPRALGLQTCCPLSGDVYRFMSGDTEDNFSQVTDFWTYTLDN-CGRKRLVRNLSEHLTEAS-QFLQERAVKLFTMVHSDFGRLMTEALNTARI-SKF----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15202-1", "uniprot_id": "CATA_YEAST", "id": "P15202-1", "name": "Peroxisomal catalase A", "aln": "-----MSKLGQEKNEVNYSDVREDRVVTNSTGNPIN-EPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNL---RDADMFWDFLTTPENQVAIHQVMILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNENPLNFFAQVEQAAFAPS-TTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVN------CPYA------------SKFFNPAIRDGPMNVNGNFGSEPTYLANDK---------------------------SYTYIQQDRPIQQHQEVWNGPAIPYHWATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGAC-PQIQQRVYDMFARVDKGLSEAIKKVAEAKHA-SELSSNSKF----------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P06115-1", "uniprot_id": "CATT_YEAST", "id": "P06115-1", "name": "Catalase T", "aln": "------------MNVFGKKEEKQEKVYSLQNGFPYSHHPYASQYSRPDGPILLQDFHLLENIASFDRERVPERVVHAKGGGCRLEFELTDSLSDITYAAPYQNVGYKCPGLVRFSTVGGESGTPDTARDPRGVSFKFYTEWGNHDWVFNNTPVFFLRDAIKFPVFIHSQKRDPQSHLNQFQDTTIYWDYLTLNPE--SIHQITYMFGDRGTPASWASMNAYSGHSFIMVNKEGKDTYVQFHVLSDTGFETLTGDKAAELSGSHPDYNQAKLFTQLQNGEKPKFNCYVQTMTPEQATKFRYSVNDLTKIWPHKEFPLRKFGTITLTENVDNYFQEIEQVAFSPTNTCIPGIKPSNDSVLQARLFSYPDTQRHRLGANYQQLPVNRPRNLGCPYSKGDSQYTAEQCPFKAVN-FQRDGPMSYY-NFGPEPNYISSLPNQTLKFKNEDNDEVSDKFKGIVLDEVTEVSVRKQEQDQIRNEHIVDAKINQYYYVYGISPLDFEQPRALYEKVYND-EQKKLFVHNVVCHACKIKDPKVKKRVTQYFGLLNEDLGKVIAECLGVPWEPVDLEGYAKTWSIASAN---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * . ** *:** : :.: *: *.:*:* :*:*.*. ** *..:: : :.:: ***.. *: *:.**.*: **.: ****: * * . * * .::**. * ::*:***:**::* :*. : **: : : : * : *.*** * . ::.*. *:: * .*. * :.* :: *::.: . .: .*** .*: : . : *.:. *:*.* .:* . :. *:**:*.: ::** .* :.* .* *:* ::** ** *: * :.* * :*:.***:* *::*:*** *: ::*** *** . * ***.* * . *.* .. . . : . :. * :: .. :: : *: * ::.: . : :. . . : ", "identical_positions": 117, "similar_positions": 147, "identity": "19.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000210-31", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P13053-1", "uniprot_id": "VDR_RAT", "id": "P13053-1", "name": "Vitamin D3 receptor", "aln": "--------------------------------MEATAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMIMKRKEEEALKDS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LRPKLSEE------------QQHIIAILLDAHHKTYDPTYADFRDFRPPVRMDGSTGSYSPRP--------------------TLSFSGNSSSSSSDLYTTSLDMMEPSGFSNLDLNGE--------------------------------------------------------------------------DSDDPSVTLDLSPLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDMSWDCGS--QDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMIQKLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFGNEIS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48281-1", "uniprot_id": "VDR_MOUSE", "id": "P48281-1", "name": "Vitamin D3 receptor", "aln": "--------------------------------MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMIMKRKEEEALKDS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LRPKLSEE------------QQHIIAILLDAHHKTYDPTYADFRDFRPPIRADVSTGSYSPRP--------------------TLSFSGDSSSNS-DLYTPSLDMMEPASFSTMDLNEE--------------------------------------------------------------------------GSDDPSVTLDLSPLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTLDDMSWDCGS--QDYKYDITDVSRAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMIQKLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFGNEIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11473-1", "uniprot_id": "VDR_HUMAN", "id": "P11473-1", "name": "Vitamin D3 receptor", "aln": "--------------------------------MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LRPKLSEE------------QQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRH----------------TPSFSGDSSSSCSDHCITSSDMMDSSSFSNLDLSEE--------------------------------------------------------------------------DSDDPSVTLELSQLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGN--QDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLEVFGNEIS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PTN2-1", "uniprot_id": "VDRA_DANRE", "id": "Q9PTN2-1", "name": "Vitamin D3 receptor A", "aln": "MLTENSAVNSGGKSKCEAGACESRVNGDATSVMDLMAVSTSATGQDEFDRNAPRICGVCGDKATGFHFNAMTCEGCKGFFRRSMKRKASFTCPFNGNCTITKDNRRHCQACRLKRCIDIGMMKEFILTDEEVQRKKDLIMKRKEEEAAREA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RKPRLSDE------------QMQIINSLVEAHHKTYDDSYSDFVRFRPPVREGPVTRSASRAA--------------------SLHSLSDASSDSFNHSPESVDTKLNFSNLLMMYQDS--------------------------------------------------------------------------GSPDSSEEDQQSRLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMSWSCGG--PDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMAICLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHP--GGRLLYAKMIQKLADLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEVS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24143-1", "uniprot_id": "HR96_DROME", "id": "Q24143-1", "name": "Nuclear hormone receptor HR96", "aln": "-------------------------------------------------MSPPKNCAVCGDKALGYNFNAVTCESCKAFFRRNALAKKQFTCPFNQNCDITVVTRRFCQKCRLRKCLDIGMKSENIMSEEDKLIKRRKIETNRAKRRLMENGTDACDADGGEERDHKAPADSSSSNLDHYSGSQDSQSCGSADSGANGCSGRQASSPGTQVNPLQMTAEKIVDQIVSDPDRASQAINRLMRTQKEAISVMEKVISSQKDALRLVSHLIDYPGDALKIISKFMNSPFNALTVFTKFMSSPTDGVEIISKIVDSPADVVEFMQNLMHSPEDAIDIMNKFMNTPAEALRILNRILSGGGANAAQQTADRKPLLDKEPAVKPAAPAERADTVIQSMLGNSPPISPHDAAVDLQYHSPGVGEQPSTSSSHPLPYIANSPDFDLKTFMQTNYNDEPSLDSDFSINSIESVLSEVIRIEYQAFNSIQQAASRVKEEMSYGTQSTYGGCNSAANNSQPHLQQPICAPSTQQLDRELNEAEQMKLRELRLASEALYDPVDEDLSALMMGDDRIKPDDTRHNPKLLQLINLTAVAIKRLIKMAKKITAFRDMCQEDQVALLKGGCTEMMIMRSVMIYDDDRAAWKVPHTKENMGNIRTDLLKFAEGNIYEEHQKFITTFDEKWRMDENIILIMCAIVLFTSARSRVIHKDVIRLEQNSYYYLLRRYLESVYSGCEARNAFIKLIQKISDVERLNKFIINVYLNVNPS-----QVEPLLREIFDLKNH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *: *.****:* *::***:***.**.****. * ****** :* ** .**.** ***::*:**** .* *:::*: *: * ..: :. : :* *..* : * * :: : . : *: . * : * . .: * .. : . . : . . * : . * :* :*.: :*:::* :** *..***: :**:.***... *::::** : : :* : .*: : .. * : . :* .:.*: ::: ** :.:. *. * . :. *: *: *:. :. .: : *:***::*:. **: : * :. . :: **: *:*. : ", "identical_positions": 100, "similar_positions": 127, "identity": "12.87%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000210-32", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15532-1", "uniprot_id": "NDKA_MOUSE", "id": "P15532-1", "name": "Nucleoside diphosphate kinase A", "aln": "-MANSERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFLQ-----------ASEDLLKEHYTDLKDRPFFTGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFQPEELVEYKSCAQNWIYE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05982-1", "uniprot_id": "NDKA_RAT", "id": "Q05982-1", "name": "Nucleoside diphosphate kinase A", "aln": "-MANSERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFIQ-----------ASEDLLKEHYIDLKDRPFFSGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEISLWFQPEELVDYKSCAQNWIYE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15531-1", "uniprot_id": "NDKA_HUMAN", "id": "P15531-1", "name": "Nucleoside diphosphate kinase A", "aln": "-MANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQ-----------ASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q01768-1", "uniprot_id": "NDKB_MOUSE", "id": "Q01768-1", "name": "Nucleoside diphosphate kinase B", "aln": "-MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLR-----------ASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIHLWFKPEELIDYKSCAHDWVYE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19804-1", "uniprot_id": "NDKB_RAT", "id": "P19804-1", "name": "Nucleoside diphosphate kinase B", "aln": "-MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLR-----------ASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFKPEELIDYKSCAHDWVYE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22392-1", "uniprot_id": "NDKB_HUMAN", "id": "P22392-1", "name": "Nucleoside diphosphate kinase B", "aln": "-MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLR-----------ASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFKPEELVDYKSCAHDWVYE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A7B3-1", "uniprot_id": "A0AB13A7B3_DANRE", "id": "A0AB13A7B3-1", "name": "Nucleoside diphosphate kinase", "aln": "MSAKTERTFIAVKPDGVQRGLMGEIIKRFEQKGFRLVAMKFLQVCVLMVDQDAVASEDLLKQHYIDLKDRPFYPGLVKYMSSGPVLAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIEVGRNIIHGSDSVDSANTEISLWFKPEELVSFKSCAQQWIYE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08879-1", "uniprot_id": "NDKA_DROME", "id": "P08879-1", "name": "Nucleoside diphosphate kinase", "aln": "MAANKERTFIMVKPDGVQRGLVGKIIERFEQKGFKLVALKFTW-----------ASKELLEKHYADLSARPFFPGLVNYMNSGPVVPMVWEGLNVVKTGRQMLGATNPADSLPGTIRGDFCIQVGRNIIHGSDAVESAEKEIALWFNEKELVTWTPAAKDWIYE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36010-1", "uniprot_id": "NDK_YEAST", "id": "P36010-1", "name": "Nucleoside diphosphate kinase", "aln": "MSSQTERTFIAVKPDGVQRGLVSQILSRFEKKGYKLVAIKLVK-----------ADDKLLEQHYAEHVGKPFFPKMVSFMKSGPILATVWEGKDVVRQGRTILGATNPLGSAPGTIRGDFGIDLGRNVCHGSDSVDSAEREINLWFKKEELVDWESNQAKWIYE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ***** :*********:.:*:.***:**::**.:*: *... *::** : :**:. :*.:* ***::. **** :**: ** :** *** .* ******** *::***: ****:*.**: ** ***: :**: : . .*:**", "identical_positions": 77, "similar_positions": 46, "identity": "46.95%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000210-34", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V816-1", "uniprot_id": "G3V816_RAT", "id": "G3V816-1", "name": "Nucleoside diphosphate kinase", "aln": "MICLVLTIFANLFPSAYSGVNERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQASEELLREHYVELRERPFYSRLVKYMGSGPVVAMVWQGLDVVRASRALIGATDPGDAMPGTIRGDFCVEVGKNVIHGSDSVESAQREIALWFREDELLCWEDSAGHWLYE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV85-1", "uniprot_id": "NDKC_MOUSE", "id": "Q9WV85-1", "name": "Nucleoside diphosphate kinase C", "aln": "MICLVLTIFANLFPSAYSGVNERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQASEELLREHYVELREKPFYSRLVKYMSSGPVVAMVWQGLDVVHASRALIGATDPGDAMPGTIRGDFCMEVGKNVIHGSDSVESAHREIALWFREAELLCWEDSAGHWLYE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13232-1", "uniprot_id": "NDKC_HUMAN", "id": "Q13232-1", "name": "Nucleoside diphosphate kinase C", "aln": "MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQASEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATNPADAPPGTIRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PTF3-1", "uniprot_id": "NDKC_DANRE", "id": "Q9PTF3-1", "name": "Nucleoside diphosphate kinase C", "aln": "MIILCLTIFANIFKPGWTGANERTFLAVKPDGVQRRLVGEIIRRFERKGFKLVGMKLLQASEAQLRQHYWELREKPFYNGLVKYMSSGPIVAMVWQGLDVVKTARKMLGETNPADSLPGTIRGDYCVEVGRNVIHGSDSVESAAREISLWFEDHELFCYEECGQHWIYA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36010-1", "uniprot_id": "NDK_YEAST", "id": "P36010-1", "name": "Nucleoside diphosphate kinase", "aln": "----------------MSSQTERTFIAVKPDGVQRGLVSQILSRFEKKGYKLVAIKLVKADDKLLEQHYAEHVGKPFFPKMVSFMKSGPILATVWEGKDVVRQGRTILGATNPLGSAPGTIRGDFGIDLGRNVCHGSDSVDSAEREINLWFKKEELVDWESNQAKWIYE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. ****:********* **.:*: ***:**:***.:**::*.: *.:** * :**: :*.:* ***::* **:* ***: .* ::* *:* .: *******: :::*:*: ******:** *** ***. **. :*. :*:* ", "identical_positions": 77, "similar_positions": 44, "identity": "45.56%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000210-35", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXL7-1", "uniprot_id": "NDK7_RAT", "id": "Q9QXL7-1", "name": "Nucleoside diphosphate kinase 7", "aln": "MKAGQQGRSCGLISPYLAPKNQSERFAFIAEWYDPNASLLRRYELLYYPVDGSVEMHDVKNRRTFLKRTKYEDLRVEDLFIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLALIKPDAVSK-AGEIIEMINKSGFTITKLRMMTLSRKEAADFHVDHHSRPFYN-ELIQFITSGPVIAMEILRDDAICEWKRLLG--PANSGIARSEAPGSVRALFGTDGIRNAAHGSDTFESAAREMELFFPSSGGCGPANTAKFTNCTCCIIKPHAISEGMLGKILIAIRDACFEISAIQMFNMDRANVEEFYEVYKGVVSEYNDMVTELYSGPCVAIEIQQSNP----TKTFREFCGPSDPEIARHLRPETLRANFGKTKVQNAVHCTDLPEDGLLEVQYFFKILDN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXL8-1", "uniprot_id": "NDK7_MOUSE", "id": "Q9QXL8-1", "name": "Nucleoside diphosphate kinase 7", "aln": "MRACQQGRSSSLVSPYMAPKNQSERFAFIAEWYDPNASLLRRYELLFYPTDGSVEMHDVKNRRTFLKRTKYEDLRLEDLFIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLALIKPDAVSK-AGEIIEMINKSGFTITKLRMMTLTRKEAADFHVDHHSRPFYN-ELIQFITSGPVIAMEILRDDAICEWKRLLG--PANSGLSRTDAPGSIRALFGTDGVRNAAHGPDTFASAAREMELFFPSSGGCGPANTAKFTNCTCCIIKPHAISEGMLGKILIAIRDACFGMSAIQMFNLDRANVEEFYEVYKGVVSEYNDMVTELCSGPCVAIEIQQSNP----TKTFREFCGPADPEIARHLRPETLRAIFGKTKVQNAVHCTDLPEDGLLEVQYFFKILDN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5B8-1", "uniprot_id": "NDK7_HUMAN", "id": "Q9Y5B8-1", "name": "Nucleoside diphosphate kinase 7", "aln": "-------------------MNHSERFVFIAEWYDPNASLLRRYELLFYPGDGSVEMHDVKNHRTFLKRTKYDNLHLEDLFIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLALIKPDAISK-AGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFN-ELIQFITTGPIIAMEILRDDAICEWKRLLG--PANSGVARTDASESIRALFGTDGIRNAAHGPDSFASAAREMELFFPSSGGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNA----TKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVQYFFKILDN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UZE3-1", "uniprot_id": "A0A8N7UZE3_DANRE", "id": "A0A8N7UZE3-1", "name": "Nucleoside diphosphate kinase 7", "aln": "---------------------MEERFAFLAEWYDPSAALLRRYQLLYYPKDGSVEMFDMKNQRTFLRRTKLEELQPEDLFVGNRVNIFSRQLNLISYGDQYTANKLGSKKERTLAMIKPDAVSK-VGDIIQMIYDANLIVTKAKMTKLTWKQAADFYMEHQSKSFFN-NLVQFVSSGPVIAMELMGDEAVSTWRKVLG--PTDSGVAQKEAAHSLRGQFGTDGTKNAGHGSDSLASAARELEYFFPSTAGHGLSNTAKYSDCTCCIIKPHAISEALTGKILKSIIENGFEISALQMFNMDRANAEEFLEVYKGVVAEYTKMVDELCSGPCMALEIHATDA----PRTFREFCGPADPEIARHLRPKTLRALYGKNKLQNGVHCTDLPEDGILEVQYFFKILDG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VH94-1", "uniprot_id": "Q9VH94_DROME", "id": "Q9VH94-1", "name": "", "aln": "-------------MKPAAIPASERRLAFVAEWFHAEAGIIRTFLITYYVSDKAVEVFDQRNKRTFLRRTKIPELTQRDFFVGSKINVFGRQFDIVDYADDTTRTNLAKYRKKGFVLLKNNMWTKHLGKFLKTLIDNKININQGMMVQFSPKMVTQFLSGKDTTDVSSSVLMNELLAGPAISLELIGDNVVETIKACAQYKSTEAETPSVKLSPSLEELFESEEIRYGFYYSD--NDNDVEMDLKFISEARHSIIKECVFKNTTLAIIKPHSIKDGLLGDIISEILSNGFRLTAMRMILMARINCEEFYEVYRGVVPEYIPMVAQLASGVCMCMEIACADPEKKTDREFRNFCGPMDPEIAKLLRPHTLRAKFGKSKVQNAVHCTDLPDDSNLELQYMFKIID-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..*:.*:***:...*.::* : : :* * :**:.* :*:****:*** :* .*:*:*.::*:*.**: ::.*.*: * :*.. ::: :.::* : :* *.::: : . : :.: * :: * . :* :.: . . *:: : :** *::*:: *:.: : .::: . . . *:. * :: : . : .* . *:: * * . . : . :.: * .*:***::.:.: *.*: * . * ::*::*: : * * *** ***:***.** ** :: ** *:.:** :. : **:**** *****: *** **** :**.*:**.*******:*. **:**:***:* ", "identical_positions": 120, "similar_positions": 142, "identity": "29.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000210-8", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04961-1", "uniprot_id": "PCNA_RAT", "id": "P04961-1", "name": "DNA sliding clamp PCNA", "aln": "MFEARLIQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVSIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIEDEEGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P17918-1", "uniprot_id": "PCNA_MOUSE", "id": "P17918-1", "name": "DNA sliding clamp PCNA", "aln": "MFEARLIQGSILKKVLEALKDLINEACWDVSSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVIKMPSGEFARICRDLSHIGDAVVISCAKNGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVHLTFALRYLNFFTKATPLSPTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIEDEEAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12004-1", "uniprot_id": "PCNA_HUMAN", "id": "P12004-1", "name": "DNA sliding clamp PCNA", "aln": "MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIEDEEGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PTP1-1", "uniprot_id": "PCNA_DANRE", "id": "Q9PTP1-1", "name": "DNA sliding clamp PCNA", "aln": "MFEARLVQGSILKKVLEALKDLITEACWDVSSSGISLQSMDSSHVSLVQLTLRSDGFDSYRCDRNLAMGVNLSSMSKILKCAGNEDIITLRAEDNADALALVFETLNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSQIGDAVMISCAKDGVKFSASGELGTGNIKLSQTSNVDKEDEAVTIEMNEPVQLIFALNYLNFFTKATPLSKTVTLSMSADIPLVVEYKIADMGHVKYYLAPKIDEESS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P17917-1", "uniprot_id": "PCNA_DROME", "id": "P17917-1", "name": "DNA sliding clamp PCNA", "aln": "MFEARLGQATILKKILDAIKDLLNEATFDCSDSGIQLQAMDNSHVSLVSLTLRSDGFDKFRCDRNLSMGMNLGSMAKILKCANNEDNVTMKAQDNADTVTIMFESANQEKVSDYEMKLMNLDQEHLGIPETDFSCVVRMPAMEFARICRDLAQFSESVVICCTKEGVKFSASGDVGTANIKLAQTGSVDKEEEAVIIEMQEPVTLTFACRYLNAFTKATPLSTQVQLSMCADVPLVVEYAIKDLGHIRYYLAPKIEDNET-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VIT0-1", "uniprot_id": "PCNA2_DROME", "id": "Q9VIT0-1", "name": "DNA sliding clamp PCNA2", "aln": "MLEARLSQTLLLKKIVDALKEIIAQGTLDCSENGLELQSMDNSHVSLVALSLASDCFEKFHCDRNVSLGLDLKSLGKVLKCANSDDAVTIKAVDRPEKITLSFESDGKERTADYELKLLNLDQDHMEIPKKDYTCFIQLPSSEFARICRDMSMFDESLTIACSSKGIRFLAKGDLGTANIQLSAGTAMD-----VSIEVQEPVTQSFAGRYLNTFTKATPLADRVKLYLSDERPLLVEYPIEDYGHIRYYLAPKVNDPDF-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15873-1", "uniprot_id": "PCNA_YEAST", "id": "P15873-1", "name": "DNA sliding clamp PCNA", "aln": "MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYRCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMDIDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLKS-GFLQFFLAPKFNDEE--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:**:: : ::*::::.:*: : : ...*: *::*.*:* ** * : : *: ::**: :::*::* *:.*:*:*... * :*: * : .: : : ** ::: ::*.:**:::* : : * : :: . : :*: **::* **:: :.::: * :.. ::* *.*::*...: : :: : :*:::** *. .** : *.:.*: * : :. : * :.:: : . *.::::****.:: . ", "identical_positions": 58, "similar_positions": 122, "identity": "22.22%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000223-14", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O14813-1", "uniprot_id": "PHX2A_HUMAN", "id": "O14813-1", "name": "Paired mesoderm homeobox protein 2A", "aln": "---MDYSYLNSYDSCVAAMEASAYGDFGACSQPGGFQYSPLRPAFPAAGPPCPALGSSNCALGALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAASAKGAAGAAGAKKGEARCSSEDDDSKESTCSPTPDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGPGPGPQPLKGALWAGVAGGGGGGPGAGAAELLKAWQPAESGPGPFSGVLSSFHRKPGPALKTNLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62066-1", "uniprot_id": "PHX2A_MOUSE", "id": "Q62066-1", "name": "Paired mesoderm homeobox protein 2A", "aln": "---MDYSYLNSYDSCVAAMEASAYGDFGACSQPGGFQYSPLRPAFPAAGPPCPALGSSNCALGALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAASAKGAAGATGAKKGEARCSSEDDDSKESTCSPTPDSTASLPPPPAPSLASPRLSPSPLPAALGSG----PGPQPLKGALWAGVAGGGGGGPGTGAAELLKAWQPAEPGPGPFSGVLSSFHRKPGPALKTNLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1RCT9-1", "uniprot_id": "F1RCT9_DANRE", "id": "F1RCT9-1", "name": "", "aln": "MYKMDYSYLNTYDSCMAAMEASAYADFNSCSQSNGFQYNPIRSGF-SSGPACAPLATASCTLGALREHQPAPYSTVPYKFFSDASGLNEKRKQRRIRTTFTSSQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAANSKASSSSGGKKPSDARSSSEDDESKESTCSPTPDSTANMSSPGARSSLSP--SPAPGPASTFSP---ASISPALKSSPWPSLGSGTPGPTHTHTQELLKAWQPADSMSGPFAGVLSSFHRK-NNTIKSNLF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *******:****:********.**.:***..****.*:*..* ::**.*..*.::.*:*****:*******:******.:.***:**************:****************************************************.:*.::.: * * .:**.*****:**************.:..* * . ** **:* *.: * . . .**.: *..:..* * . : : *********:. .***:********* . ::*:***", "identical_positions": 186, "similar_positions": 68, "identity": "64.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000308-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K0Y2-1", "uniprot_id": "A0A0G2K0Y2_RAT", "id": "A0A0G2K0Y2-1", "name": "", "aln": "MNKLYIGNLSDHAGPADLESVFKDAKIPVAGPFLVKTGYAFVDCPDEGWALKAIEALSGKMELHGKPMEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVN-TDSETAVVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDETAAQQSPSPQLRGRRGPGQRGSSRQTSPGSVSKQK-PCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENTGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKFT------EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFP------PTSG--MPPPTSGPPSAMTPPYPQF-EQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPD----AKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTP---DENDQVVVKITGHFYACQVAQRKIQEILTQVK-------------QHQQQKALQSGAPQSRRK-----------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CPN8-1", "uniprot_id": "IF2B3_MOUSE", "id": "Q9CPN8-1", "name": "Insulin-like growth factor 2 mRNA-binding protein 3", "aln": "MNKLYIGNLSDHAGPADLESVFKDAKIPVAGPFLVKTGYAFVDCPDEGWALKAIEALSGKMELHGKPMEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVN-TDSETAVVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDETAAQQNPSPQLRGRRGPGQRGSSRQASPGSVSKQK-PCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENTGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKFT------EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGSVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFP------PTSG--MPPPTSGPPSTLTPPYPQF-EQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPD----AKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQSLSSAEVVVPRDQTP---DENDQVVVKITGHFYACQVAQRKIQEILTQVK-------------QHQQQKALQSGPPQSRRK-----------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00425-1", "uniprot_id": "IF2B3_HUMAN", "id": "O00425-1", "name": "Insulin-like growth factor 2 mRNA-binding protein 3", "aln": "MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGKIELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVN-TDSETAVVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSSRQGSPGSVSKQK-PCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKFT------EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFP------PTSG--MPPPTSGPPSAMTPPYPQF-EQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPD----AKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTP---DENDQVVVKITGHFYACQVAQRKIQEILTQVK-------------QHQQQKALQSGPPQSRRK-----------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PW80-1", "uniprot_id": "IF2B3_DANRE", "id": "Q9PW80-1", "name": "Insulin-like growth factor 2 mRNA-binding protein 3", "aln": "MNKLYIGNVSEQASALDLESIFEQWKIPFSAPFLVKSGYAFVDCPDEKVAMRAIDTLSGKVELHGKVLEVEHSVPKRQRSCKLQIRNIPPHMQWEVLDGLLAQYGTVESCEQVN-TDTETAVVNVRYGAKDQAREAMDKLNGFLMENYALKVSYIPDETAAADAP--AVGGRRGFNPRGPPRQGSPSLGARPKLQSDVPLRLLVPTQFVGAIIGKEGATIRNITKQTHSKIDIHRKENAGAAEKPITVHSTPEGCSSACRNIMEIMQKEAIDTKIT------EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQDLTLYNPERTITVKGTLDACAKAEEEIMKKVRESYENDVAAMHLQSNLIPGLNLNALGLFPG-----AASGGISPSVVSGPPPGAQAGYQSFGAQMESETVHLFIPALAVGAIIGKQGQHIKQLSRFAGASIKIAPADGID----AKQRMVIISGPPEAQFKAQGRIFGKLKEENFFGPKEEVKLEAHIKVPSFAAGRVIGKGGKTVNELQNLTSAEVVVPRDQTP---DENDQVVVKITGHFYASQLAQRKIQEIISQVR-------------RQQQPKPSAAGPPVARRK-----------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9NF14-1", "uniprot_id": "M9NF14_DROME", "id": "M9NF14-1", "name": "", "aln": "-------MASELDQFADLELSKEDREQIFDPPLDRQQ--------------------------------LEGAGTSSVTTSKILISGIPMQTRFEDIEPLLKPYGIVKQCEAISSKDQNTQTVHITFENPEQAQRAAVGLNGVEFEGSKLHAEQLDKNQRR---------------SQRNQRNPYPGMPGPGR-QADFPLRILVQSEMVGAIIGRQGSTIRTITQQSRARVDVHRKENVGSLEKSITIYGNPENCTNACKRILEVMQQEAISTNKGELSPECSEICLKILAHNNLIGRIIGKSGNTIKRIMQDTDTKITVSSINDINSFNLERIITVKGLIENMSRAENQISTKLRQSYENDLQAMAPQSLMFPGLHPMAMMSTPGNGMVFNTSMPFPSCQSFAMSKTPASVVPPVFPNDLQETTYLYIPNNAVGAIIGTRGSHIRSIMRFSNASLKIAPLDADKPLDQQTERKVTIVGTPEGQWKAQYMIFEKMREEGFMCGTDDVRLTVELLVASSQVGRIIGKGGQNVRELQRVTGSVIKLPEHALAPPSGGDEETPVHIIGLFYSVQSAQRRIRAMMLSTNPPPITKKQKAAKEQLQQQQQSLAGAASSGSQQQQPQSPSQQQALPPQLHHQPVSSASSSSTPPAHHQQQASTAATSHQLQQQQPSPPPPGNATAAAAQQQQQLASSQQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: *** :: : . *: : :* : .. *: * .** : ::* :: ** ** *:.** :. .* :* .*:: : :**:.* ***. :*. *:. : .: : *: *. . : .*.***:** :::******::*:***.**:*:::::*:*****.*: **.**: ..**. : **: *:*:*::** . : .** ********::**:***.*..:*:* ********:*.::::. :* ** ***** :: ::**::* .*:*:*****: :* *: ::***: *: * :* . . . . . : **.:*:** :******.:*.**:.: **:.**:**** :. . . * * * *.**.*:*** *: *::**.*. .::*:* ..: *.* .**:*****:.*.*** ::.: : :*.. . . :::. *:* * **: * ***:*: :: ... : ** : :*.. : : ", "identical_positions": 189, "similar_positions": 184, "identity": "27.27%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000322-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P20472-1", "uniprot_id": "PRVA_HUMAN", "id": "P20472-1", "name": "Parvalbumin alpha", "aln": "MSMTDLLNAEDIKKAVGAFSATDSFDHKKFFQMVGLKKKSADDVKKVFHMLDKDKSGFIEEDELGFILKGFSPDARDLSAKETKMLMAAGDKDGDGKIGVDEFSTLVAES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I8V0-1", "uniprot_id": "PRV2_DANRE", "id": "Q9I8V0-1", "name": "Parvalbumin-2", "aln": "MAFAGILKDEDVAAALKDCAAADSFNYKNFFAKVGLSAKSPDDIKKAFFVIDQDKSGFIEEDELKLFLQNFSAGARALTDAETKAFLSAGDSDGDGKIGVDEFALLVKA-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:::.:*: **: *: :*:***::*:** ***. **.**:**.*.::*:*********** ::*:.**..** *: *** :::***.***********: ** ", "identical_positions": 59, "similar_positions": 33, "identity": "53.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000322-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5SX39-1", "uniprot_id": "MYH4_MOUSE", "id": "Q5SX39-1", "name": "Myosin-4", "aln": "--MSSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKSSVFVVDAKESYVKATVQSREGGKVTAKTEGGAT-VTVKDDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKEEATSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKK-PELIEMLLITTNPYDFAYVSQG-EITVPSIDDQEELMATDTAVDILGFSADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNSVGALAKSMYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNTLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIDWEFIDFGMDLAACIELIEK---PMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAK-GKAEAHFSLVHYAGTVDYNIIGWLDKNKDPLNETVVGLYQKSGLKTLAFLFSG-GQAAEAEG-GG--GKKGGKK--KGSSFQTVSALFRENLNKLMTNLKSTHPHFVRCLIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKAS-----EKLLGSIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAVCRGYLMRVEFKKMMERRESIFCIQYNVRAFMN-VKHWPWMKLYFKIKPLLKSAETEKEMANMKEDFEKAKEDLAKSEAKRKELEEKMVALMQEKNDLQLQVQAEADGLADAEERCDQLIKTKIQLEAKIKELTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDENIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG--ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMETVSKAKGNLEKMCRTLEDQLSEVKTKEEEQQRLINELSTQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEESKAKNALAHALQSARHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKIKKQIDQEKSELQASLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEAIRNLRNTQGMLKDTQLHLDDALRGQDDLKEQLAMVERRANLMQAEIEELRASLEQTERSRRVAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELENEVENEQKRNIEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKIQHELEEAEERADIAESQVNKLRVKSREVHTKVISEE----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q29RW1-1", "uniprot_id": "MYH4_RAT", "id": "Q29RW1-1", "name": "Myosin-4", "aln": "--MSSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKSSVFVVDAKESYVKATVQSREGGKVTAKTEGGAT-VTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKEEAPSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQVMSNKK-PELIEMLLITTNPYDFAYVSQG-EITVPSIDDQEELMATDTAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNSVGALAKAMYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNTLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEK---PMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAK-GKAEAHFSLVHYAGTVDYNIIGWLDKNKDPLNETVVGLYQKSGLKTLAFLFSG-GQAAEAEG-GG--GKKGGKK--KGSSFQTVSALFRENLNKLMTNLKSTHPHFVRCLIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKAS-----EKLLGSIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAVCRGYLMRVEFRKMMERRESIFCIQYNVRAFMN-VKHWPWMKLYFKIKPLLKSAETEKEMATMKEDFEKAKEDLAKSEAKRKELEEKMVALMQEKNDLQLQVQAEADGLADAEERCDQLIKTKIQLEAKIKELTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDENIVKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG--ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMETVSKAKGNLEKMCRTLEDQLSEVKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEESKAKNALAHALQSARHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKIKKQIDQEKSELQASLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEAIRNLRNTQGMLKDTQLHLDDALRGQDDLKEQLAMVERRANLMQAEIEELRASLEQTERSRRVAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELENEVENEQKRNIEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKIQHELEEAEERADIAESQVNKLRVKSREVHTKVISEE----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y623-1", "uniprot_id": "MYH4_HUMAN", "id": "Q9Y623-1", "name": "Myosin-4", "aln": "--MSSDSEMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKVTAKTEAGAT-VTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKK-PELIEMLLITTNPYDFAFVSQG-EITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEK---PMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAK-GKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLFSG-AQTAEAEG-GG--GKKGGKK--KGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKAS-----EKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMN-VKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG--ATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSREVHTKVISEE----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SX40-1", "uniprot_id": "MYH1_MOUSE", "id": "Q5SX40-1", "name": "Myosin-1", "aln": "--MSSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKSSVFVVDAKESFVKATVQSREGGKVTAKTEGGTT-VTVKDDQVYPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEATSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKK-PDLIEMLLITTNPYDYAFVSQG-EITVPSIDDQEELMATDSAIDILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEK---PMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAK-GKVEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSMKTLAYLFSGAAAAAEAES-GGGGGKKGAKK--KGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKAS-----EKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQAMCRGYLARVEYQKMVERRESIFCIQYNVRAFMN-VKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKAKENLAKAEAKRKELEEKMVALMQEKNDLQLQVQSEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDVENDKQQLDEKLKKKEFEMSNLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG--ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMEVISKSKGNLEKMCRTLEDQVSELKTKEEEQQRLINELTAQRGRLQTESGEYSRQLDEKDSLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKYEETHAELEASQKESRSLSTELFKIKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQIEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHIRVVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHSNRMAAEALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNVEAIKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQSKVKAYKRQAEEAEEQSNVNLAKFRKIQHELEEAEERADIAESQVNKLRVKSREVHTKIISEE----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12882-1", "uniprot_id": "MYH1_HUMAN", "id": "P12882-1", "name": "Myosin-1", "aln": "--MSSDSEMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSREGGKVTAKTEAGAT-VTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKK-PDLIEMLLITTNPYDYAFVSQG-EITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEK---PMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAK-GKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLALLFVG-ATGAEAEA-GG--GKKGGKK--KGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKAS-----EKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMN-VKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG--ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSREVHTKIISEE----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3UW82-1", "uniprot_id": "MYH2_MOUSE", "id": "G3UW82-1", "name": "Myosin-2", "aln": "--MSSDAEMAVFGEAAPYLRKSEKERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSKDAGKVTVKTEAGAT-LTVKEDQIFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKEEATSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKK-PELIEMLLITTNPYDYPFVSQG-EISVASIDDQEELMATDSAIDILGFTNDEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQGLNSADLLKALCYPRVKVGNEYVTKGQTVEQVTNAVGALAKAMYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEK---PMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSANFQKPKVVK-GKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNETVVGLYQKSSVKTLAYLFSG-AQTAEAEASSGGAAKKGAKK--KGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQYIDSKKAS-----EKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNIRAFMN-VKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDDLAKSEAKRKELEEKMVSLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDERLKKKEFEMSNLQSKIEDEQAIGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG--ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQVSELKSKEEEQQRLINDLTTQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEVKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKYEETHAELEASQKEARSLGTELFKMKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHIRVVESMQSTLDAEIRSRNDAIRIKKKMEGDLNEMEIQLNHSNRMAAEALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLSKFRKIQHELEEAEERADIAESQVNKLRVKSREVHTKIISEE----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKX2-1", "uniprot_id": "MYH2_HUMAN", "id": "Q9UKX2-1", "name": "Myosin-2", "aln": "--MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKVTVKTEGGAT-LTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKK-PELIEMLLITTNPYDYPFVSQG-EISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEK---PMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVVK-GKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSG-AQTAEGEG-AGGGAKKGGKK--KGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKAS-----EKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMN-VKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG--ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKVISEE----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P13542-1", "uniprot_id": "MYH8_MOUSE", "id": "P13542-1", "name": "Myosin-8", "aln": "MSAGSDAEMAIFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSVIQSKDGGKVTVKTESGAT-LTVKEDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKEE--SGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKK-PELIEMLLITTNPYDYAFVSQG-EITVPSIDDQEELMATDSAIDILGFSPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQCLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEK---PLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKPTK-GKAEAHFSLVHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFST-YASAEADG----GAKKGAKK--KGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFIDSKKAS-----EKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGYLMRVEYQKMLLRRESIFCIQYNVRAFMN-VKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDENIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG--ATSAQVEMNKKRETEFQKLRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLSSNAEAIAKAKGNLEKMCRTLEDQVSELKSKEEEQQRLINELTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKRQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKVLSEWRQKYEETQAELESCQKESRTLSTELFKVKNAYEESLDHLETLRRENKNLQQEISDLTEQIAEGGKHIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHVRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13535-1", "uniprot_id": "MYH8_HUMAN", "id": "P13535-1", "name": "Myosin-8", "aln": "MSASSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVTVKTEGGAT-LTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKDE--SGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKK-PDLIEMLLITTNPYDYAFVSQG-EITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEK---PLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVVK-GKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFST-YASAEADS----SAKKGAKK--KGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFIDSKKAS-----EKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMN-VKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG--ATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UKX3-1", "uniprot_id": "MYH13_HUMAN", "id": "Q9UKX3-1", "name": "Myosin-13", "aln": "--MSSDAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTRENDKVIVKTLDDRM-LTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKET-QPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKK-PELIDLLLISTNPFDFPFVSQG-EVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEK---PMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAK-GKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLSFLFSN-YAGAETGDSGG--SKKGGKK--KGSSFQTVSAVFRENLNKLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEGQFIDSKNAS-----EKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMN-VKHWPWMNLFFKIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASG--ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQKMEE-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AFM0-1", "uniprot_id": "A0A8I6AFM0_RAT", "id": "A0A8I6AFM0-1", "name": "", "aln": "--MSTDAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFAVDDKEMYVKGMIQSRENDKVIVKTLDDRE-LTLNSDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKK------------RQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEQ-QPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKK-PELIDLLLISTNPFDFPFVSQG-EVTVASIDDSEELLATDNAIDILGFSPEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEK---PMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAK-GKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLSFLFSN-YAGAEAGDSTG--GKKGGKK--KGSSFQTVSAVFRENLNKLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEGQFIDSKNAS-----EKLLNSIDVDREQFRFGHTKVFFKAGLLGLLEEMRDEKLVTLMTRTQAVCRGYLMRVEFKKMMERREAIFCIQYNVRSFMN-VKHWPWMNLFFKIKPLLKSAEAEKEMATMKEDFERAKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKIQLEAKVKELNERLEEEEETNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEETISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLMKINVKLEQQTDDLEGSLEQEKKLRADLERVKRKLEGDLKMSQESIMDLENDAQQLEEKLKKKEFEMSQLQTRIDDEQILSLQLQKKIKELQARTEELEEEIEAEHTVRAKIEKQRSDLARELEEISERLEEASG--ATSAQIEMNKKREAEFQKLRRDLEEATLQHEATAATLRKKHADTVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEAVSKSKSNMERMCRSVEDQFNEIKAKDDQQTQLIHDLNMQKARLQTQNGELNHQVEEKESLVSQLTKSKQALTQQLEELKRQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTEASNSKCASLEKTKQRLQGEVDDLMLDLEKANTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTEIFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEVEKTKKQMEQEKSDLQAALEEVEGSLEHEESKILRVQLELSQVKSELDRKVTEKDEEIEQIKRNSQRAVEAMQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLSHANRQVAETQKHLRTVQGQLKDSQLHLDDAQRSNEDLKEQLAIVERRNGLLQEELEEMKVALEQTERTRRLSEQELLDSSDRVQLLHSQNTSLINTKKKLEADLAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELESELDAEQKRGAEALKGAHKYERKVKEMTYQAEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAEERADIAESQVNKLRAKSRDVGGQKMEE-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B8A568-1", "uniprot_id": "B8A568_DANRE", "id": "B8A568-1", "name": "", "aln": "--MSTDAEMAVYGKAAIYLRKPEKERVEAQNKPFDAKTACYVVDDKELYVKGTIKSKDGGKVTVITLDTKEEKVVKEDDVHPMNPPKFDKIEDMAMMTHLNEPSVLYNLKERYAAWMIYTYSGLFCATVNPYKWLPVYDAEVVAAYRGKK------------RMEAPPHIFSVSDNAYQFMLTDRENQSVLITGESGAGKTVNTKRVIQYFATVAVQGPEKKKEQASGKMQGSLEDQIIAANPLLEAYGNAKTVRNDNSSRFGKFIRIHFGTSGKLASADIETYLLEKSRVTFQLPDERGYHIFYQMMTNHK-PELIEMTLITTNPYDFPMCSQG-QITVASIDDKEELVATDTAIDILGFNNEEKMGIYKFTGAVLHHGNMKFKQKQREEQAEPDGTEEADKIGYLLGLNSADMLKALCYPRVKVGNEFVTKGQTVPQVYNSVSALSKSIYERMFLWMVVRINQMLDTKQQRNFFIGVLDIAGFEIFDFNSMEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIVWEFIDFGMDLAACIELIEK---PLGIFSILEEECMFPKATDTSFKNKLYDQHLGKCNAFQKPKPAK-GKAEAHFSLVHYAGTVDYNISGWLDKNKDPLNESVVQLYQKSSVKLLATLYPP--VVEETGG-----GKKGGKK--KGGSMQTVSSQFRENLGKLMTNLRSTHPHFVRCLIPNESKTPGLMENFLVIHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASVIPEGQFIDNKKAS-----EKLLGSIDVNHDEYRFGHTKVFFKAGLLGTLEEMRDEKLASLVTMTQALCRAYLMRREFVKMMERRDAIYTIQYNVRSFMN-VKHWPWMKVYYKIKPLLKSAETEKELATMKEDFVKCKEDLAKAEAKKKELEEKMVALLQEKNDLQLAVASESENLSDAEERCEGLIKSKIQLEAKLKETTERLEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAAQDESIGKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKSKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDLENDKQQSEEKLKKKDFETSQLLSKIEDEQSLGAQLQKKIKELQARIEELEEEIEAERAARAKVEKQRADLSRELEEISERLEEAGG--ATAAQIEMNKKREAEFQKLRRDLEESTLQHEATAAALRKKQADSVAELGEQIDNLQRVKQKLEKEKSEYKMEIDDLSSNMEAVAKAKANLEKMCRTLEDQLSEIKSKNDENLRQINDLSAQRARLQTENGEFGRQLEEKEALVSQLTRGKQAFTQQIEELKRQIEEEVKAKNALAHAVQSARHDCDLLREQFEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEESKKKLAQRLQEAEEQIEAVNSKCASLEKTKQRLQGEVEDLMIDVERANALAANLDKKQRNFDKVLAEWKQKYEEGQAELEGAQKEARSLSTELFKMKNSYEETLDQLETLKRENKNLQQEISDLTEQLGETGKSIHELEKSKKAVETEKAEIQTALEEAEGTLEHEESKILRVQLELNQVKSEIDRKLAEKDEEIEQIKRNSQRITDSMQSTLDSEVRSRNDALRIKKKMEGDLNEMEIQLSHANRQAAEAQKQLRNVQAQLKDAQLHLDDAVRGQEDMKEQVAMVERRNTLMQSEIEELRAALEQTERGRKVAEQELVDASERVGLLHSQNTSLLNTKKKLEADLVQIQSEVEDTVQEARNAEDKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEVTVKDLQHRLDEAENLAMKGGKKQLQKLESRVRELESEVEAEQRRGADAVKGVRKYERRVKELTYQTEEDKKNVNRLQDLVDKLQLKVKAYKRQSEEAEEQANSHLSKLRKVQHELEEAEERADIAESQVNKLRAKSRDSGKGKDAAE----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P05661-3", "uniprot_id": "MYSA_DROME", "id": "P05661-3", "name": "Myosin heavy chain, muscle", "aln": "--MPKPVANQEDEDPTPYLFVSLEQRRIDQSKPYDSKKSCWIPDEKEGYLLGEIKATKGDIVSVGLQGGET-RDLKKDLLQQVNPPKYEKAEDMSNLTYLNDASVLHNLRQRYYNKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRGKR------------RNEVPPHIFAISDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGAS----KKTDEAAKSKGSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAGADIETYLLEKARVISQQSLERSYHIFYQIMSGSV-PGVKDICLLTDNIYDYHIVSQG-KVTVASIDDAEEFSLTDQAFDILGFTKQEKEDVYRITAAVMHMGGMKFKQRGREEQAEQDGEEEGGRVSKLFGCDTAELYKNLLKPRIKVGNEFVTQGRNVQQVTNSIGALCKGVFDRLFKWLVKKCNETLDTQQKRQHFIGVLDIAGFEIFEYNGFEQLCINFTNEKLQQFFNHHMFVLEQEEYKREGIDWAFIDFGMDLLACIDLIEK---PMGILSILEEESMFPKATDQTFSEKLTNTHLGKSAPFQKPKPPKPGQQAAHFAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKKSQNKLLIEIFAD--HAGQSGG--GEQAKGGRGK--KGGGFATVSSAYKEQLNSLMTTLRSTQPHFVRCIIPNEMKQPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRYKIMCPKLLQG--VEKDKKAT-----EIIIKFIDLPEDQYRLGNTKVFFRAGVLGQMEEFRDERLGKIMSWMQAWARGYLSRKGFKKLQEQRVALKVVQRNLRKYLQ-LRTWPWYKLWQKVKPLLNVSRIEDEIARLEEKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQDYQERNAKLTAQKNDLENQLRDIQERLTQEEDARNQLFQQKKKADQEISGLKKDIEDLELNVQKAEQDKATKDHQIRNLNDEIAHQDELINKLNKEKKMQGETNQKTGEELQAAEDKINHLNKVKAKLEQTLDELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKELSSITAKLEDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEELGERLEEAGG--ATSAQIELNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNKLKAKAEKEKNEYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSIENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERATLLGKFRNLEHDLDNLREQVEEEAEGKADLQRQLSKANAEAQVWRSKYESDGVARSEELEEAKRKLQARLAEAEETIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIANAAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEIDRRIQEKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAEANALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRKNHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQAISKFRAKGRAGSVGRGASPAPRATSVRPQFDGLAFPPRFDLAPENEF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08964-1", "uniprot_id": "MYO1_YEAST", "id": "P08964-1", "name": "Myosin-1", "aln": "----MTGGQSCSSNMIVWIPDEKEVFVKGELMSTDINKNKFTGQEEQIGIVHPLDSTEVS----------NLVQVRISDVFPVNPSTFDKVENMSELTHLNEPSVLYNLEKRYDCDLIYTYSGLFLVAINPYHNLNLYSEDHINLYHNKHNRLSKSRLDENSHEKLPPHIFAIAEEAYENLLSEGKDQSILVTGESGAGKTENTKKILQYLASITSGSPSNIAPVSGSSIVESFEMKILQSNPILESFGNAQTVRNNNSSRFGKFIKIEFNEHGMINGAHIEWYLLEKSRIVHQNSKERNYHIFYQLLSGLDDSELKNLRLKSRNVKDYKILSNSNQDIIPGINDVENFKELLSALNIIGFSKDQIRWIFQVVAIILLIGNIEFVSDRAEQASFKN---DVSAICSNLGVDEKDFQTAILRPRSKAGKEWVSQSKNSQQAKFILNALSRNLYERLFGYIVDMINKNLDHGSATLNYIGLLDIAGFEIFENNSFEQLCINYTNEKLQQFFNNHMFVLEQSEYLKENIQWDYIDYGKDLQLTIDLIESKGPPTGVLPLLDEEAVLPKSTDESFYSKLISTWDQNSSKFKRSRLKN------GFILKHYAGDVEYTVEGWLSKNKDPLNDNLLSLLSSSQNDIISKLFQPEGEKSSSAGVEANISNQEVKKSARTSTFKTTSSRHREQQITLLNQLASTHPHFVRCIIPNNVKKVKTFNRRLILDQLRCNGVLEGIRLAREGYPNRIAFQEFFQRYRILYPENSTTTTFSSKLKASTKQNCEFLLTSLQLDTKVYKIGNTKLFFKAGVLADLEKQKDVKLNNIMIKLTATIRGYTVRKEITYHLQKLKKTRVIGNTFRLYNRLVKEDPWFNLFIRIKPLLTSSNDMTRTKKFNEQINKLKNDLQEMESKKKFLEEKNQKTVNELENTQDLLNQEKENLRKNESLLNRVKTSSETLQKQFDDLVSEKDEISREKLEVAQNLEEAHQKIQGLQETIREREATLEKLHSKNNELIKQISDLNCDISKEQSSQSLIKESKLKLENEIKRLKDVINSKEEEIKSFNDKLSSSEEDLDIKLVTLEKNCNIAMSRLQSLVTENSDLRSKNE---NFKKEKAALNNQLKNKESELLKMKEKIDNHKKELATFSKQRDDAVSEHGKITAELKETRIQLTEYKSNYQKIKEEYSNFQRETKEQEQKKRNSLVESLNDSKIKELEARLSQEISLNQYLNKRISGNSVETNISSTRRSTSYSDDPLDKEDIIKKYYDLQLAFTEITRNLENEIEEKKNLISRLRFTETRLASSSFEDQKIKAQMKKLKKLIQDMDP-SIPLDSILNEPLDNCPDKESDINKLMLEVDYLKRQLDIETRAHYDAENAISALHSKFRKIQGESSLSSSDIYKLKFEASEERVKSLEDKLKTMP-LRDRTNLPVGDIIKNRDSISKYEEEIRYYKLENYKLQEILNESNGKLSQLTLDLRQSKSKEALLSEQLDRLQKDLESTERQKELLSSTIKQQKQQFENCMDDLQGNELRLREHIHALKQAEEDVKNMASIIEKLKTQNKQKEKLIWEREMERNDSDMQLQETLLELKRVQDVKKILSDDLAHLKERLSAVE------------DRSQYTDEINRLKEELNCSLKAETNLKKEFATLKYKLETSTNDSEAKISDLLKQLDHYTKVVEMLNNEKDAISLAEKELYQKYEALNTECESLKGKIVSLTKIKQELESDLNQKTDALQISNAALSSSTQKNKEITEK-IKYLEETLQLQMEQNSRNGELVKTLQASCNG---YKDKFDDEKQKNIDLYEE---NQTLQKLNTDLQLQLKNLHERLSDTTEKNAWLSK--IHELENMVSLETDLKYEEMKKNKSLERAVEELQTKNSQQTDVIELANKNRSEFEEATLKYEAQISDLEKYISQQELEMKKSIRDNSSYRDKVQEMAQEIEFWKSRYESTMIGSKNIDSNNAQSKIFS-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: . : . * :. : : :: : :.: . . :. . : :**..::* *:*: :*:*::..**:**.:** :******** .::***: :* *:.*: : : *****:::: ** :*:: :**:*:********* ***::: *:*:: .. ::* ::: :**:**::***:****:*********:*.*. * : .*.** *****:*: * **.******: :. . : :: * : * *: *:. : :..*:* *:: *.:*:**. :: :::... :: *.::* . *: : : . : :: . : ** *.*:*:*::.:. *. :.**.: :::::* ::* *: ** . :**:*********: * :******:**********:*******.** :*.* * :**:* ** *:***. * *::.:*:**.::**:** :* .** . :. *::.: : * : **** *.*.: ***.*******:.:: ..* . : :: . .: * : . : *.*: .:*: .*:. * **:******:***: * .: *::.** *********:.*:*:*.*: : :* **::: .. .. :*: * :: ::: :::*:**:**:**:*. :*: :* :* :: * *.: * : : ..* : . :: ** ::: ::****. :. . ::*. : :: :* ** : * : * * . :. : . *: :. : .. : . . :: : .: .:: . *:. * : * .: * ...: ::: :*. ::: :. :.:.* : :: : :: *:::: : . . *: * :**:: :: . : . :.**: :* : :.: :: ::.*: * : ::::.: .:: .: :. :: *:: : :: :.: .: .* .:: .. :* .: .:*..: *:. : . . : : : : :. . . .. * . *: : :: . : : * : : . . . : :: ::.: : ::* .: ::: *: : * : : . . . :: : . . . .*: *: . : : * . *:: * : ** . : : *:: :. . ::.:* :: :::: .:: ::* : . . : : : :. ::: .. :: . .* . *: ..: **: . :..* * : : : * * :: : : : *:..: : ...: : : .*. *. : .: : * : ::. *.:* . : : :* *:* . *: * :.. : . : . : . . .: : : . : : : : :* *:: : :: * .: :: : : . . :*: : :.:: . :: : *. *. : * :* * :::.. :: :*:*: **.:: .* :::** * . * :: . : .: : : .: : * .** .::: . * : ::. :: .: * : :.:::* :. :: :. .. .: ", "identical_positions": 351, "similar_positions": 671, "identity": "17.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000328-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09087-1", "uniprot_id": "ABDB_DROME", "id": "P09087-1", "name": "Homeobox protein abdominal-B", "aln": "MQQHHLQQQQQQQQQQEQQHLQEQQQHLQQLHHHAHHHLPQPLHTTSHHHSAHPHLQQQQQQQQHAVVASSPSSVLQQQQQQSTPTTHSTPTHAVMYEDPPPVPLVAVQQQHLPAPQQQQQLQQQQQQQQQQLATTPVAGALSPAQTPTGPSAQQQQHLTSPHHQQLPQQQTPNSVASGASSNLQQQQQQQNAAVAPGQTQIVAPTTASVSPSSVSSQKEDINMSIQLAPLHIPAIRAGPGFETDTSAAVKRHTAHWAYNDEGFNQHYGSGYYDRKHMFAYPYPETQFPVGQYWGPNYRPDQTTSAAAAAAYMNEAERHVSAAARQSVEGTSTSSYEPPTYSSPGGLRGYPSENYSSSGASGGLSVGAVGPCTPNPGLHEWTGQVSVRKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRMKNKKNSQRQANQQNNNNNSSSNHNHAQATQQHHSGHHLNLSLNMGHHAAKMHQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9PWL7-1", "uniprot_id": "HXBAA_DANRE", "id": "Q9PWL7-1", "name": "Homeobox protein Hox-B10a", "aln": "----------------------------------------MALHRHPFVHGAASWDGEQ----------------------------------------PSPVQLPHISACPFTSSGRKE----------------------DPFYFTLDPTGQARQPLDISAFSRIMTDMGSLNSAD---------DHRPETSFYSGHKLLSLNTDTDPESPSLSSHSD----SQHLHSLSLSAPCS----ETDN----------------------------KHDMQYLAMESTKYPS--QWS------ESRTNRSIITTLSISQRSKDDIEPNNLQTDFTRGDKTPREK---------TQDVTLENAANG-----------------WLSAKAGRKKRCPYSKHQILELEKEFLFNMYLTRERRLEISRSINLTDRQVKIWFQNRRMKLKKMTREHRTRDPGTSFTV---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .** .. *.* . :* *.** * :. :.:. ::: .* . .*:.* :* * . ..:: : . . *. ::: :::. .*:. : * :. ...*:**:.: * :* .* :.* : ***. ::.* . .*::* *. :: : : : :. ::* . :.:: * . :.* . ::: : ..*:.* * . : **** ****.* ********** *:::::* *::*.::**:************* ** ::.: .:: ... : ", "identical_positions": 77, "similar_positions": 116, "identity": "15.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000328-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A0V9-1", "uniprot_id": "D4A0V9_RAT", "id": "D4A0V9-1", "name": "Homeobox protein", "aln": "MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPAVFSTSWAPVPSQSSVVYHPYGPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRHYALKPDAYPGRRA-DCGPGDGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09633-1", "uniprot_id": "HXC9_MOUSE", "id": "P09633-1", "name": "Homeobox protein Hox-C9", "aln": "MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPAVFSTSWAPVPSQSSVVYHPYGPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRHYALKPDAYPGRRA-DCGPGDGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31274-1", "uniprot_id": "HXC9_HUMAN", "id": "P31274-1", "name": "Homeobox protein Hox-C9", "aln": "MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPAVFSTSWAPVPSQSSVVYHPYGPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRHYALKPDAYPGRRA-DCGPGEGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9YGS6-1", "uniprot_id": "HXC9A_DANRE", "id": "Q9YGS6-1", "name": "Homeobox protein Hox-C9a", "aln": "MSATGPISNYYVDSLINHESEDVLASRFTATGPISSSSRPTPLVPECADYPSCSFAPKPPVFTTSWAPVHSQSSVVYHPYTHQPHLGTDSRYVRSWLEPIPGTVSFPGYAGNSRHYGLKPDTFQDPRAGDCLGSNGRTYTDYLYCSAVDIREKQ-QNTPSPETESLSSGKHKDDKAELDPNNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKNDSKEQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************.*:.**:*****.***. .:::**: ***:*:*:*********.**:****** ********** *****:*:**:*:****:.*:****.:....***.****:: . ** ** .:**:*.**:* *. ::*:: *. ****:::*:..***::**:***.**************************************************************************.*.::.", "identical_positions": 187, "similar_positions": 59, "identity": "71.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000329-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60709-1", "uniprot_id": "ACTB_HUMAN", "id": "P60709-1", "name": "Actin, cytoplasmic 1", "aln": "-MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60711-1", "uniprot_id": "ACTB_RAT", "id": "P60711-1", "name": "Actin, cytoplasmic 1", "aln": "-MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60710-1", "uniprot_id": "ACTB_MOUSE", "id": "P60710-1", "name": "Actin, cytoplasmic 1", "aln": "-MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7ZVI7-1", "uniprot_id": "ACTB1_DANRE", "id": "Q7ZVI7-1", "name": "Actin, cytoplasmic 1", "aln": "-MDEEIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMGTAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITSLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P63260-1", "uniprot_id": "ACTG_MOUSE", "id": "P63260-1", "name": "Actin, cytoplasmic 2", "aln": "-MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63261-1", "uniprot_id": "ACTG_HUMAN", "id": "P63261-1", "name": "Actin, cytoplasmic 2", "aln": "-MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10987-1", "uniprot_id": "ACT1_DROME", "id": "P10987-1", "name": "Actin-5C", "aln": "MCDEEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P02572-1", "uniprot_id": "ACT2_DROME", "id": "P02572-1", "name": "Actin-42A", "aln": "MCDEEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIVAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53501-1", "uniprot_id": "ACT3_DROME", "id": "P53501-1", "name": "Actin-57B", "aln": "MCDDEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMESCGIHETVYNSIMKCDVDIRKDLYANIVMSGGTTMYPGIADRMQKEITSLAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKEEYDESGPGIVHRKCF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P02574-1", "uniprot_id": "ACT4_DROME", "id": "P02574-1", "name": "Actin, larval muscle", "aln": "MCDEEASALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDCYVGDEAQSKRGILSLKYPIEHGIITNWDDMEKVWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRTPEALFQPSFLGMESCGIHETVYQSIMKCDVDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P60010-1", "uniprot_id": "ACT_YEAST", "id": "P60010-1", "name": "Actin", "aln": "-MDSEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGIMVGMGQKDSYVGDEAQSKRGILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKSNREKMTQIMFETFNVPAFYVSIQAVLSLYSSGRTTGIVLDSGDGVTHVVPIYAGFSLPHAILRIDLAGRDLTDYLMKILSERGYSFSTTAEREIVRDIKEKLCYVALDFEQEMQTAAQSSSIEKSYELPDGQVITIGNERFRAPEALFHPSVLGLESAGIDQTTYNSIMKCDVDVRKELYGNIVMSGGTTMFPGIAERMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLTTFQQMWISKQEYDESGPSIVHHKCF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: :***:********************************:********.*************:*:*******:********:************************:***:************** **:**:********:********:******:*.**** *::*******:***************:******:************************** *** *:*:******************** **:**:**.**:*:.**.:*.::********:**:**.* *:******:****:*******:****::*:**:*******************:*********:*******.***:***", "identical_positions": 315, "similar_positions": 52, "identity": "83.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000329-10", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TQQ0-1", "uniprot_id": "OR4E2_MOUSE", "id": "Q7TQQ0-1", "name": "Olfactory receptor 4E2", "aln": "-------------------------------------MGAL--NQT-RVTEFIFLGLTDNWVLEILFFVPFTVTYMLTLLGNFLIVVTIVFTPRLHNPMYFFLSNLSFIDICHSSVTVPKMLEGLLLERKTISFDNCIAQLFFLHLFACSEIFLLTIMAYDRYVAICIP---------LHYSNVMNMKVCVQLVFALWLGGTIHSLVQTFLTIRLPYCGPNIIDSYFCDVPPVIKLACTDTYLTGILIVSNSGTISLVCFLALVTS--YTVILFSLRKQSAEGRRKALSTCSAHFMVVA--LFFGPCIFLYTRP----DSSFS---IDKVVSVFYTVVTPLLNPLIYTLRNEEVKTAMKHLRQRRICS--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ADC0-1", "uniprot_id": "D4ADC0_RAT", "id": "D4ADC0-1", "name": "Olfactory receptor", "aln": "-------------------------------------MGAL--NQT-RVTEFVFLGLTDNWVLEILFFIPFTVTYVLTLLGNVLIVVTIVFTPRLHNPMYFFLSNLSFIDICHSSVTVPKMLEGLLLVRKTISFDNCIAQLFFLHLFACAEIFLLTIMAYDRYVAICIP---------LHYPNVMNMKVCVQLVFALWLGGTVHSLVQTFLTIRLPYCGPNTIDSYFCDVPPVIKLACTDTYLTGILIVSNSGTISLVCFLALVTS--YTVILFSLRKQSAEGRRKALSTCSAHFMVVA--LFFGPCIFIYTWP----DTSFS---IDKVVSVFYTVVTPLLNPLIYTLRNEEVKTSMKHLRQRRICS--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGC2-1", "uniprot_id": "OR4E2_HUMAN", "id": "Q8NGC2-1", "name": "Olfactory receptor 4E2", "aln": "-------------------------------------MDSL--NQT-RVTEFVFLGLTDNRVLEMLFFMAFSAIYMLTLSGNILIIIATVFTPSLHTPMYFFLSNLSFIDICHSSVTVPKMLEGLLLERKTISFDNCITQLFFLHLFACAEIFLLIIVAYDRYVAICTP---------LHYPNVMNMRVCIQLVFALWLGGTVHSLGQTFLTIRLPYCGPNIIDSYFCDVPLVIKLACTDTYLTGILIVTNSGTISLSCFLAVVTS--YMVILVSLRKHSAEGRQKALSTCSAHFMVVA--LFFGPCIFIYTRP----DTSFS---IDKVVSVFYTVVTPLLNPFIYTLRNEEVKSAMKQLRQRQVFFTKSYT---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R0K4-1", "uniprot_id": "Q9R0K4_MOUSE", "id": "Q9R0K4-1", "name": "Olfactory receptor", "aln": "----------------------------------MEKAVLI--NETSVMS-FRLTGLSTNPLVQMAVFFIFLIFYVLTLVGNILIVITIIYDRRLHTPMYFFLSNLSFIDVCHSTVTVPKMLSDTFSEEKLISFDACVVQMFFLHLFACTEIFLLTVMAYDRYVAICKP---------LQYMTIMNWKVCMMLAAALWTGGTIHSISLTSLTIKLPYCGPDEIDNFFCDVPQVIKLACTDTHIIEILIVSNSGLISVVCFVVLVVS--YAVILVSLRQQISDGKRKALSTCAAHLTVVT--LFLGHCIFIYSRP----STSLP---EDKVVSVFFTAVTPLLNPIIYTLRNEDMKSALNKLIKRREK---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C645-1", "uniprot_id": "OR4E1_HUMAN", "id": "P0C645-1", "name": "Olfactory receptor 4E1", "aln": "----------------------------------MEEAILL--NQTSLVTYFRLRGLSVNHKARIAMFSMFLIFYVLTLIGNVLIVITIIYDHRLHTPMYFFLSNLSFIDVCHSTVTVPKMLRDVWSEEKLISFDACVTQMFFLHLFACTEIFLLTVMAYDRYVAICKP---------LQYMIVMNWKVCVLLAVALWTGGTIHSIALTSLTIKLPYCGPDEIDNFFCDVPQVIKLACIDTHVIEILIVSNSGLISVVCFVVLVVS--YAVILVSLRQQISKGKRKALSTCAAHLTVVT--LFLGHCIFIYSRP----STSLP---EDKVVSVFFTAVTPLLNPIIYTLRNEEMKSALNKLVGRKERKEEK-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2I3BQG5-1", "uniprot_id": "A0A2I3BQG5_MOUSE", "id": "A0A2I3BQG5-1", "name": "Olfactory receptor", "aln": "-------------------------MSAPTSVYQGSNSVLL--NQT-LVTEFLLLGVTDIQELNPILFVTVLAMYFVNVAGNGAILLIVISDPRLHSPMYFFLGNLACLDICFSTVTVPKILDNFFSTSKAISFLGCITQLYFFHLLGSTEALLLAVMAFDRFVAICRP---------LHYPSIMNGQVCIQVAISIWAIPFVHALVHSILTSQLNFCGSNQIHHFFCDVKPLLELACGNTELNRWLLNTFTGTFAIGLFFLTFLSYFYIITYLFLKTRSCSMLHKALSTCASHFMVVM--IFYAPVLFIYINP--DSGSSLE---KDRIIAVMYTVVTPALNPLIYTLRNKEVRGALNRKLRILL----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2I3BRX0-1", "uniprot_id": "A0A2I3BRX0_MOUSE", "id": "A0A2I3BRX0-1", "name": "Olfactory receptor", "aln": "-------------------------MSAPTSVSQEGNSVLL--NHT-LVTEFLLLGVTDIQELNPILFVTVLAMYFVNVAGNGAILMIVISDPRLHLPMYFFLGNLACLDICFSTVTVPKMLENFFSTSKAISFLGCITQLHFFHFLGSTEALLLTVMAFDRFVAICRP---------LHYPAIMNSQVCIQVAISIWAIPFLHALVHSILTSQLNFCGSNHIHHFFCDVKPLLELACGNTELNRWLLNTLTGTVAIGLFFLTFLSYFYIVTYLFLKTRSCSMLHKALSTCASHFMVVM--IFYAPVLFIYINP--DSGSSLE---KDRIIAVMYTVVTPALNPLIYTLRNKEVRGALNRKIRILL----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58182-1", "uniprot_id": "O12D2_HUMAN", "id": "P58182-1", "name": "Olfactory receptor 12D2", "aln": "---------------------------------------ML--NTT-SVTEFLLLGVTDIQELQPFLFVVFLTIYFISVTGNGAVLMIVISDPRLHSLMYFFLGNLSYLDICYSTVTLPKMLQNFLSTHKAISFLGCISQLHFFHSLGSTESMLFAVMAFDLSVAICKP---------LRYTVIMNPQLCTQMAITIWVIGFFHALLHSVMTSRLNFCGSNRIHHFLCDIKPLLKLACGNTELNQWLLSTVTGTIAMGPFFLTLLSYFYIITYLFFKTRSCSMLCKALSTCASHFMVVI--LFYAPVLFTYIHP--ALESFMD---QDRIVAIMYTVVTPVLNPLIYTLRNKEVKGALGRVIRRL-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VG96-1", "uniprot_id": "Q8VG96_MOUSE", "id": "Q8VG96-1", "name": "Olfactory receptor", "aln": "---------------------------------------ME--NST-SVDEFLLLGLTSVQKLQPIIFVMFLTIYLLNLVGNGVILMIVTLERRLHSPMYFFLGNLSCLDICYSSVTLPKVLINLLSRRRAISFLGCITQLYFFHFLGSTEAILLAVMAFDRFVAICSP---------LRYTAIMNPQLCILLAATAWFTSFFYALLHSVMTAHLNFCHSHKLSHFFCDVKPLLEVACGNTVLNQWLLSVVTGSISMGAFLLILLSYFYIIAFLLFKNRSCRMLKKALSTCTSHFMVVC--LFYGPVGFTYIRPATASASSMS---EDRVVAIIYSAVTPVLNPLIYTLRNKEVMLALKKNFGKKLFKGN------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGF7-1", "uniprot_id": "O12D3_HUMAN", "id": "Q9UGF7-1", "name": "Olfactory receptor 12D3", "aln": "---------------------------------------ME--NVT-TMNEFLLLGLTGVQELQPFFFGIFLIIYLINLIGNGSILVMVVLEPQLHSPMYFFLGNLSCLDISYSSVTLPKLLVNLVCSRRAISFLGCITQLHFFHFLGSTEAILLAIMAFDRFVAICNP---------LRYTVIMNPQVCILLAAAAWLISFFYALMHSVMTAHLSFCGSQKLNHFFYDVKPLLELACSDTLLNQWLLSIVTGSISMGAFFLTLLSCFYVIGFLLFKNRSCRILHKALSTCASHFMVVC--LFYGPVGFTYIRP--ASATSMI---QDRIMAIMYSAVTPVLNPLIYTLRNKEVMMALKKIFGRKLFKDWQQHH--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LI97-1", "uniprot_id": "A0ABK0LI97_RAT", "id": "A0ABK0LI97-1", "name": "Olfactory receptor", "aln": "-----------------------------------------------MVIEFLFSVFPPLHEGGLLFFILLILVYAFIISGNLVIFVAVQLDLALHTPMYFFISVLSFLEIWYTTTTIPKMLSSLVSEKKTISLGGCLMQMYFFHSLGITEGCVLTAMSIDRYIAICYP---------LRYPTIMTSKLCIQLTAGSCFCGFLLVLPEIAWIATLPFCGSNKIHQIFCDFTPVLRLACTDTSLVV-IVDAIHAVEILASFLVIALSY-IRIIMVILGMPSAEGRHKAFSTCAAHLAVFL--LFFGSVAVMYLRF--SATYSVF---WDTVIAVTFVILAPFLNPIIYSLRNKEMKDAIGRLFH-RKRDARAQK---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGW6-1", "uniprot_id": "OR6K6_HUMAN", "id": "Q8NGW6-1", "name": "Olfactory receptor 6K6", "aln": "---------MKQYSVGNQHSNYRSLLFPFLCSQMTQLTASG--NQT-MVTEFLFSMFPHAHRGGLLFFIPLLLIYGFILTGNLIMFIVIQVGMALHTPLYFFISVLSFLEICYTTTTIPKMLSCLISEQKSISVAGCLLQMYFFHSLGITESCVLTAMAIDRYIAICNP---------LRYPTIMIPKLCIQLTVGSCFCGFLLVLPEIAWISTLPFCGSNQIHQIFCDFTPVLSLACTDTFLVV-IVDAIHAAEIVASFLVIALSY-IRIIIVILGMHSAEGHHKAFSTCAAHLAVFL--LFFGSVAVMYLRF--SATYSVF---WDTAIAVTFVILAPFFNPIIYSLKNKDMKEAIGRLFHYQKRAGWAGK---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6A5L7-1", "uniprot_id": "A0A8I6A5L7_RAT", "id": "A0A8I6A5L7-1", "name": "Olfactory receptor", "aln": "-------------------------------------MRIN--RTT-SVTEFLFSGLPEFEDGRFLFFIPLFFIYVFIVIGNLIVFFAVRMDTRLHNPMYNFISIFSFLEIWYTTATIPKMLSNLISKRRTISLIGCLLQMYFFHSLGNSEGILLTTMAIDRYIAICNP---------LRYPTIMTPRLCAQLSAGSCIFGFLVLLPEIAWISTLPFCGPNQIHQIFCDFEPVLRLACTDTSMIL-VEDVVHAVAIIFSVLVIAFSY-IRIITVILRIPSGEGRRKAFSTCAAHLGVFL--MFYGSVSLMYLRF--SATFPPV---LDTAIALMFAVLAPFFNPIIYSLRNKDMKTAIKKLLSSPTMLPTSAS---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGY3-1", "uniprot_id": "OR6K3_HUMAN", "id": "Q8NGY3-1", "name": "Olfactory receptor 6K3", "aln": "--------------------MCWTMPSPFTG-SSTRNMESG--NQS-TVTEFIFTGFPQLQDGSLLYFFPLLFIYTFIIIDNLLIFSAVRLDTHLHNPMYNFISIFSFLEIWYTTATIPKMLSNLISEKKAISMTGCILQMYFFHSLENSEGILLTTMAIDRYVAICNP---------LRYQMIMTPRLCAQLSAGSCLFGFLILLPEIVMISTLPFCGPNQIHQIFCDLVPVLSLACTDTSMIL-IEDVIHAVTIIITFLIIALSY-VRIVTVILRIPSSEGRQKAFSTCAGHLMVFP--IFFGSVSLMYLRF--SDTYPPV---LDTAIALMFTVLAPFFNPIIYSLRNKDMNNAIKKLFCLQKVLNKPGG---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AP46-1", "uniprot_id": "A0A8I6AP46_RAT", "id": "A0A8I6AP46-1", "name": "Olfactory receptor", "aln": "-------------------------------------MDHV--NCT-WNWIFILAGFNTSGTLQQLAVFGTLCIYLLTLAGNLFIIVLVQADSGLSTPMYFFISVLSFLEIWYVSTTVPTLLHTLLHGHSPIPSAACFIQLYVFHSLGMTECYLLGVMALDRYLAICRP---------LHYHSLMSRQVQRELVLITWVAGFSAALVPAGLTATLPYC-LKEVAHYFCDLGPVMQLACVDTSWHARVYIAVIGMINTCNLVFILGLY-GGIVKAVLRLPSAASRAKAFSTCSSHITVVT--LFFGSAFIVYVGP--PEIRAEG---RGKLIALVYTLFTPFFNPIIYTLRNKEVKAAFKRVTQRIKGVLG------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZIK6-1", "uniprot_id": "D3ZIK6_RAT", "id": "D3ZIK6-1", "name": "Olfactory receptor", "aln": "-------------------------------------MDHV--NYT-WTRTFILAGFTTSGTLQQLSVFGTLCIYLLTIAGNIFIIVLVQADSGLSTPMYFFISVLSFLEIWYVSTSVATLLHTLLHGHSPIPSAACFIQLYVFHSLGMTECYLLSVMALDRYLAICRP---------LHYHALMSRQVKIQLVLITWVAGFSVALVPAGLTASLPYC-LKEVAHYLCDLEPVIRLACVDTSWHARVYITVIGIIITCNLVSILGLY-GGIAKAVLRLPSAASRAKAFSTCSSHITVVT--LFYGSAFIVYVGP--PEIRAEG---RDKLIALVYTLFTPFFNPIIYTLRNKEVKAAFKRVTQRIQGVLS------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q8M2-1", "uniprot_id": "E9Q8M2_MOUSE", "id": "E9Q8M2-1", "name": "Olfactory receptor", "aln": "-------------------------------------MDHV--NYT-WTRTFILAGFTTSGTLQHLAVFGTLCIYLLTLAGNLFIIVLIQADSGLSTPMYFFISVLSFLELWYVSTTVPTLLHTLLHGPSPIPSSACFVQLYVFHSLGMTECYLLGVMALDRYLAICRP---------LHYHALMSRQVQKQLVGVTWLAGFSAALVPAGLTASLPYC-LKEVAHYFCDLAPVMQLACVDTSWHARLYIAVIGMINTCNLTFILGLY-GGIVRAVLKLPSAASRAKAFSTCSSHITVVT--LFFGSAFIVYVGP--PEIRAEG---RDKLIALVYTLLTPFFNPIIYTLRNKEVKEAFKRVTQRINAVLK------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TRV9-1", "uniprot_id": "Q7TRV9_MOUSE", "id": "Q7TRV9-1", "name": "Olfactory receptor", "aln": "-------------------------------------MDHV--NYT-WTRTFILAGFTTSGALRPLAFLGTLCIYLLTLAGNLFIIVLVQADSGLSTPMYFFISVLSFLELWYVSTTVPTLLHTLLHGHSPIPSSACFVQLYVFHSLGMTECYLLGVMALDRYLAICRP---------LHYHALMSRQVQLWLAGATWVAGFSAALVPACLTASLPYC-LKEIAHYFCDLAPLMRLACVSTRWHARVHGAVIGVATGCNFVLILGLY-GGILTAVLKLPSAASRAKAFSTCSSHMTVVA--LFYASAFTVYVGS--PQSRPEG---TDKLIALVYALLTPFLNPIIYSLRNKEVKEAVKRVSEKIRTLLRDT----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGG9-1", "uniprot_id": "Q8VGG9_MOUSE", "id": "Q8VGG9-1", "name": "Olfactory receptor", "aln": "-------------------------------------MDG---DNQTIVTEFILLGLTRQSEKEEVVFGLFLWMYLVTISGNLLIILAISCDPHLHTPMYFFLANLSSVDISAPSVIVPKALVNHMLGSKSISYTGCMTQIYFFITFSNMDGFLLSVMAYDRYVAICHP---------LHYTMMMRPRLCVLLVAISWAITNLHALLHTLLMVRLTFCSHNAVHHFFCDPYPILKLSCSDTFINDLMVFTIGGLVFMTPFTCIIVSYAYIFSKVLK-LKSAHGIRKALSTCGSHLTVVS--LFYGAILGIYMHP--SSTYTVQ----DTVATVIFTVVTPMVNPFIYSLRNRDIKGALRKIILRS-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGH1-1", "uniprot_id": "Q8VGH1_MOUSE", "id": "Q8VGH1-1", "name": "Olfactory receptor", "aln": "-------------------------------------MDG---DNETMVAEFLLLGLSGKSEQEEVVFGMFLGMYLVTISGNLLIILAISCDPHLHTPMYFFLANLSSVDICFSSVTVPKALVNHVLGSKSISYTECMIQIYFFITFINMDGFLLSVMAYDRYVAICHP---------LHYTMMMRSRLCVLLVAISWVITNLHALLHTLLMVRLTFCSHNAVHHFFCDPYPILKLSCSDTFINDLMVFTVGGVIFLTPFSCIVVSYVYIFSKVLK-IPSARGIRKALSTCGSHLTVVS--LFYGAILGVYMRP--SSSYSLQ----DTVATVIFTVVTPLVNPFIYSLRNQDMKGALRKIMLRS-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NHA8-1", "uniprot_id": "OR1FC_HUMAN", "id": "Q8NHA8-1", "name": "Putative olfactory receptor 1F12P", "aln": "-------------------------------------MEG---KNQTNISEFLLLGFSSWQQQQVLLFALFLCLYLTGLFGNLLILLAIGSDHCLHTPMYFFLANLSLVDLCLPSATVPKMLLNIQTQTQTISYPGCLAQMYFCMMFANMDNFLLTVMAYDRYVAICHP---------LHYSTIMALRLCASLVAAPWVIAILNPLLHTLMMAHLHFCSDNVIHHFFCDINSLLPLSCSDTSLNQLSVLATVGLIFVVPSVCILVSYILIVSAVMK-VPSAQGKLKAFSTCGSHLALVI--LFYGAITGVYMSP--LSNHSTEK---DSAASVIFMVVAPVLNPFIYSLRNNELKGTLKKTLSRPGAVAHACNPSTLGGRGGWIMRSGDRDHPG------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VGK1-1", "uniprot_id": "Q8VGK1_MOUSE", "id": "Q8VGK1-1", "name": "Olfactory receptor", "aln": "-------------------------------------ME-----NESSVSEFFLQGISGFSEQQQLLYGLFLCMYLVTLTGNVLIILAIGSDPHLHTPMYFFLANLSFADMGLISSTVTKMLFNVQTRCHTISYTGCLTQMYFFLMFGDLDSFLLAVMAYDRYVAICHP---------LHYSTIMSARVCALMLALCWVLTNIVALTHTLLMARLSFCVVGEIAHFFCDITPVLKLSCSDTHVNELMVFALGGTVLMVPFVCIVISYIHIVFAILK-VRTPGGGTKAFSTCSSHLCVVC--VFYGTLFSAYLCP--PSVVST---EKDVAAAAMYTVVTPMLNPFIYSLRNKDMKGALKRLLCHRKFLS-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGK0-1", "uniprot_id": "Q8VGK0_MOUSE", "id": "Q8VGK0-1", "name": "Olfactory receptor", "aln": "-------------------------------------ME-----NQSSVSEFFLRGISGFPEQQQLLYGLFLCMYLVTLTGNVLIILAISCDPHLHTPMYFFLANLSFADMGLISSAVTKMLFNVQTQRHTISYTGCLTQMYLFMMFGDLDSFFLAVMAYDRYVAICHP---------LHYSTIMSARVCALMLALCWVLTNIVALTHTLLMTRLSFCVVGEIAHFFCDITSVMKLSCSDTHVNELVLSGFGGTVLMVPFVSIVISYVRIVFAVLR-VQTSGGSSKAFSTCSSHLCVVC--VFYGTLFSVYLFP--SSGETT---EKDVVAAAMYTVVTPMLNPFIYSLRNKDMKGALKRLLCHRRKFSP------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGS0-1", "uniprot_id": "OR1N1_HUMAN", "id": "Q8NGS0-1", "name": "Olfactory receptor 1N1", "aln": "-------------------------------------ME-----NQSSISEFFLRGISAPPEQQQSLFGIFLCMYLVTLTGNLLIILAIGSDLHLHTPMYFFLANLSFVDMGLTSSTVTKMLVNIQTRHHTISYTGCLTQMYFFLMFGDLDSFFLAAMAYDRYVAICHP---------LCYSTVMRPQVCALMLALCWVLTNIVALTHTFLMARLSFCVTGEIAHFFCDITPVLKLSCSDTHINEMMVFVLGGTVLIVPFLCIVTSYIHIVPAILR-VRTRGGVGKAFSTCSSHLCVVC--VFYGTLFSAYLCP--PSIASE---EKDIAAAAMYTIVTPMLNPFIYSLRNKDMKGALKRLFSHRSIVSS------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VGJ8-1", "uniprot_id": "Q8VGJ8_MOUSE", "id": "Q8VGJ8-1", "name": "Olfactory receptor", "aln": "-------------------------------------MGKISRVNQSVASDFLLLGLSEQPGEQPLLFGIFLGMYLVTMVGNLLIIFVISSDAHLHTPMYFFLANLSLTDACFTSASVPKMLANIYTQSQTISYSGCLTQLYFLLMFGGLDNCLLAVMAYDRYVAICQP---------LHYSTAMSPQLCALMLCTCWVLTNCPALMHTLLLTRVAFCAHTAIPHFYCDPSALLKLACSDTHINELMIITMGLVFLAVPLMLIVFSYVCISWAVLG-IPSSGGRWKAFSTCGSHLTVVL--LFYGSLMGVYLLP--PSTHST---ERESRAAVLYMIVIPMLNPFIYSLRNRDMKEAMGKLFGGGKTVFLL-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGR9-1", "uniprot_id": "OR1N2_HUMAN", "id": "Q8NGR9-1", "name": "Olfactory receptor 1N2", "aln": "-------------------------------------MGKPGRVNQTTVSDFLLLGLSEWPEEQPLLFGIFLGMYLVTMVGNLLIILAISSDPHLHTPMYFFLANLSLTDACFTSASIPKMLANIHTQSQIISYSGCLAQLYFLLMFGGLDNCLLAVMAYDRYVAICQP---------LHYSTSMSPQLCALMLGVCWVLTNCPALMHTLLLTRVAFCAQKAIPHFYCDPSALLKLACSDTHVNELMIITMGLLFLTVPLLLIVFSYVRIFWAVFV-ISSPGGRWKAFSTCGSHLTVVL--LFYGSLMGVYLLP--PSTYST---ERESRAAVLYMVIIPTLNPFIYSLRNRDMKEALGKLFVSGKTFFL------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TQU7-1", "uniprot_id": "Q7TQU7_MOUSE", "id": "Q7TQU7-1", "name": "", "aln": "-------------------------------------MAP---ENQTTVLEFHLMGLSEDPDLQTILFGLFLSMYLVTVFGNLLIILAIISDSHLHTPMYFFLCNLSLVDIFFCSTTVPKMLVNIQTQSRAISFTGCLVQMYAFHLFGTIDSFLLAVMAIDRLVAIAYP---------LRYSVLMSPHVCALLVGGTWVITNLQSLVHTCLMAQLTFCARSEIPHFFCDLMPLLKLSCSDTHINELVIFAFGIVMGLSPLSCILVSYICIFRAVFR-IPSAQGKWKAFSTCGSHLTVVS--LFYGTIFTGYLLP--ASPSSS---QKDKAAALMFGVVIPTLNPFIYSLRNKDMKAALRKLGSKAVS----------------------------------FQS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60431-1", "uniprot_id": "OR1I1_HUMAN", "id": "O60431-1", "name": "Olfactory receptor 1I1", "aln": "-------------------------------------MEP---EKQTEISEFFLQGLSEKPEHQTLLFTMFLSTYLVTIIGNALIILAIITDSHLHTPMYFFLFNLSLVDTLLSSTTVPKMLANIQAQSRAIPFVGCLTQMYAFHLFGTMDSFLLAVMAIDRFVAIVHP---------QRYLVLMCSPVCGLLLGASWMITNLQSLIHTCLMAQLTFCAGSEISHFFCDLMPLLKLSGSDTHTNELVIFAFGIVVGTSPFSCILLSYIRIFWTVFK-IPSTRGKWKAFSTCGLHLTVVS--LSYGTIFAVYLQP--TSPSSS---QKDKAAALMCGVFIPMLNPFIYSIRNKDMKAALGKLIGKVAVPCPRPEQLLDVYHVPGSLLAARDTEMHPIPYPGGVQSLAGNRDME", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH06-1", "uniprot_id": "OR1P1_HUMAN", "id": "Q8NH06-1", "name": "Olfactory receptor 1P1", "aln": "--------------------------MGLTQDFFPPTSELLEGGNQTSTFEFLLWGLSDQPQQQHIFFLLFLWMYVVTVAGNLLIVLAIGTDTHLHTPMYFFLASLSCADIFSTSTTVPKALVNIQTQSRSISYAGCLAQLYFFLTFGDMDIFLPATMAYDRYVAICHL---------LHYMMIMSLHRCAFLVTACWTLTSLLAMTRTFLIFRLSLCSK-ILPGFFCDLGPLMKVSCSDAQVNELVLLFLGGAVILIPFMLILVSYIRIVSAILR-APSAQGRRKAFSTCDSHLVVVA--LFFGTVIRAYLCP--SSSSSNS-VKEDTAAAVMYTVVTPLLNPFIYSMRNKDMKAAVVRLLKGRVSFSQGQ----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGA1-1", "uniprot_id": "OR1M1_HUMAN", "id": "Q8NGA1-1", "name": "Olfactory receptor 1M1", "aln": "-------------------------------------MEP---RNQTSASQFILLGLSEKPEQETLLFSLFFCMYLVMVVGNLLIILAISIDSHLHTPMYFFLANLSLVDFCLATNTIPKMLVSLQTGSKAISYPCCLIQMYFFHFFGIVDSVIIAMMAYDRFVAICHP---------LHYAKIMSLRLCRLLVGALWAFSCFISLTHILLMARLVFCGSHEVPHYFCDLTPILRLSCTDTSVNRIFILIVAGMVIATPFVCILASYARILVAIMK-VPSAGGRKKAFSTCSSHLSVVA--LFYGTTIGVYLCP--SSVLTT---VKEKASAVMYTAVTPMLNPFIYSLRNRDLKGALRKLVNRKITSSS------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VFM9-1", "uniprot_id": "OR1M1_MOUSE", "id": "Q8VFM9-1", "name": "Olfactory receptor 1M1", "aln": "-------------------------------------MEP---QNHTSASEFILLGLSEKPDHDPVLFSLFLCMYMITVVGNLLIILAISFDSHLHTPMYFFLANLSLVDFCLATNTVPKMLVNIQTRNKSISYPCCLTQMYFFHFFGIMDSVLIAVMAYDRFVAICHP---------LHYSTIMSPRLCGLLVGVPWVYSCFISLTHILLMARLVFCGKNELPHYFCDLTPLLRLSCTDTTVNKIFVLIVAGMVIATPFVCILASYARIIVAIMK-VPSAGGRKKAFSTCSSHLSVVA--LFYGTTIGVYLCP--SSVRTA---VKEKASAVMYTAVTPMLNPFIYSLRNRDLKGALKKIINRKISTSS------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30953-1", "uniprot_id": "OR1E1_HUMAN", "id": "P30953-1", "name": "Olfactory receptor 1E1", "aln": "-------------------------------------MMG---QNQTSISDFLLLGLPIQPEQQNLCYALFLAMYLTTLLGNLLIIVLIRLDSHLHTPMYLFLSNLSFSDLCFSSVTIPKLLQNMQNQDPSIPYADCLTQMYFFLLFGDLESFLLVAMAYDRYVAICFP---------LHYTAIMSPMLCLALVALSWVLTTFHAMLHTLLMARLCFCADNVIPHFFCDMSALLKLAFSDTRVNEWVIFIMGGLILVIPFLLILGSYARIVSSILK-VPSSKGICKAFSTCGSHLSVVS--LFYGTVIGLYLCS--SANSST---LKDTVMAMMYTVVTPMLNPFIYSLRNRDMKGALSRVIHQKKTFFSL-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47887-1", "uniprot_id": "OR1E2_HUMAN", "id": "P47887-1", "name": "Olfactory receptor 1E2", "aln": "-------------------------------------MMG---QNQTSISDFLLLGLPIQPEQQNLCYALFLAMYLTTLLGNLLIIVLIRLDSHLHTPVYLFLSNLSFSDLCFSSVTMPKLLQNMQNQDPSIPYADCLTQMYFFLYFSDLESFLLVAMAYDRYVAICFPMHYTAICFLLHYTAIMSPMLCLSVVALSWVLTTFHAMLHTLLMARLCFCADNVIPHFFCDMSALLKLACSDTRVNEWVIFIMGGLILVIPFLLILGSYARIVSSILK-VPSSKGICKAFSTCGSHLSVVS--LFYGTVIGLYLCP--SANSST---LKDTVMAMMYTVVTPMLTPFIYSLRNRDMKGALERVICKRKNPFLL-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8WZA6-1", "uniprot_id": "OR1E3_HUMAN", "id": "Q8WZA6-1", "name": "Olfactory receptor 1E3", "aln": "-------------------------------------MMK---KNQTMISEFLLLGLPIQPEQQNLFYALFLAVYLTTLLGNLLVIVLIRLDSHLHMPMYLCLSNLSFSDLCFSSVTMPKLLQNMQSQNPSIPFADCLAQMYFHLFYGVLESFLLVVMAYHCYVAICFP---------LHYTTIMSPKCCLGLLTLSWLLTTAHATLHTLLMARLSFCAENVIPHFFCDTSTLLKLACSNTQVNGWVMFFMGGLILVIPFLLLIMSCARIVSTILR-VPSTGGIQKAFSTCGPHLSVVS--LFYGTIIGLYLCP--LTNHNT---VKDTVMAVMYTGVTHMLNPFIYSLRNRDMRGNPGQSLQHKENFFVFKIVIVGILPLLNLVGVVKLIMKYHSKSVA------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZVZ1-1", "uniprot_id": "D3ZVZ1_RAT", "id": "D3ZVZ1-1", "name": "Olfactory receptor", "aln": "-------------------------------------MTQ---DNESTVSDFNLLGLPIRAEDQGVYSVLFLIMYLTTVLGNLLIILLIRLDPHLHTPMYFFLSHLALTDISFSSVTAPKMLMNMLTHSQSISYAGCVSQVYFYIAFSDLDSFLLTSMAYDRYVAICHP---------LHYNTIMSQNLCVLLLVMSWALSSANALVHTLLLARLSHFRNNTISHYFCELSALLKLSSSDTTINKMVILPLGTVVITLPFVLILVSYGCIGVTILK-IPSINGIYKTLSTCGSHLCVVS--LYYGAIIGLYFVP--SSNNTN---DQDAIVAVIYTVVTPMLNPFIYSLRNRDMKGALKNILSRR-LCSQ------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LIW9-1", "uniprot_id": "A0ABK0LIW9_RAT", "id": "A0ABK0LIW9-1", "name": "Olfactory receptor", "aln": "-------------------------------------MME---TNQSTVSEFILLGLPIQPEDQAVYSVLFLAMYMTTVLGNLLIILLIRLDSHLHTPMYFFLSHLAFTDISFSSVTAPKMLMNMLTHSQSISYAGCVSQIYFFLLFGCIDNFLLTSMAYDRYVAICHP---------LHYTTVMSQSLCVLLVMISWVFSSTNGLVHTLLFARLSHFKDNTVHHFFCDLSALLKLSISDTTINELVILTLAVVVITVPFICILISYGHIGATILR-TPTIQGICKALSTCGSHLCVVF--LYYGAIIGLYFFP--SSNNTN---AKDVIASVLYTVVTPMLNPFIYSLRNRDMKGALKNTLSRR-LCSH------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGS3-1", "uniprot_id": "OR1J1_HUMAN", "id": "Q8NGS3-1", "name": "Olfactory receptor 1J1", "aln": "-------------------------------------MSP---ENQSSVSEFLLLGLPIRPEQQAVFFALFLGMYLTTVLGNLLIMLLIQLDSHLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQHLAVFYKGCISQTYFFIFFADLDSFLITSMAYDRYVAICHP---------LHYATIMTQSQCVMLVAGSWVIACACALLHTLLLAQLSFCADHIIPHYFCDLGALLKLSCSDTSLNQLAIFTAALTAIMLPFLCILVSYGHIGVTILQ-IPSTKGICKALSTCGSHLSVVT--IYYRTIIGLYFLP--PSSNTN---DKNIIASVIYTAVTPMLNPFIYSLRNKDIKGALRKLLSRSGAVAHACNLNTLGG---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3Z9I7-1", "uniprot_id": "D3Z9I7_RAT", "id": "D3Z9I7-1", "name": "Olfactory receptor", "aln": "-------------------------------------MRL---KNHSSVSEFLLLGLPIRAEQSGIFFSMFLAMYLTTVLGNLLIILLIRLDSHLHTPMYFFLSHLAFTDISFSSVTVPKMLTKVPNQNIPITYEGCVSQTYFFIFFADLDSFLITSMAYDRYMAICHP---------LNYTTIMNQSRCATLVAISWIIASACALLHTLLLDQLSFCADHTIPHFFCDLGALLKLSCSDTSLNQLVIFTAGLAAIMLPFLCILISYGHIGFTILQ-VPSTKGICKALSTCGSHLSVVA--LYYGSIIGLYFLP--PSNSTI---NNNIVASVMYTVVTPMLNPFIYSLRNKDMKGALRKLLSKKVEFSN------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGS2-1", "uniprot_id": "OR1J2_HUMAN", "id": "Q8NGS2-1", "name": "Olfactory receptor 1J2", "aln": "-------------------------------------MSP---ENQSSVSEFLLLGLPIRPEQQAVFFTLFLGMYLTTVLGNLLIMLLIQLDSHLHTPMYFFLSHLALTDISFSSVTVPKMLMDMRTKYKSILYEECISQMYFFIFFTDLDSFLITSMAYDRYVAICHP---------LHYTVIMREELCVFLVAVSWILSCASSLSHTLLLTRLSFCAANTIPHVFCDLAALLKLSCSDIFLNELVMFTVGVVVITLPFMCILVSYGYIGATILR-VPSTKGIHKALSTCGSHLSVVS--LYYGSIFGQYLFP--TVSSSI---DKDVIVALMYTVVTPMLNPFIYSLRNRDMKEALGKLFSRATFFSW------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGS1-1", "uniprot_id": "OR1J4_HUMAN", "id": "Q8NGS1-1", "name": "Olfactory receptor 1J4", "aln": "-------------------------------------MKR---ENQSSVSEFLLLDLPIWPEQQAVFFTLFLGMYLITVLGNLLIILLIRLDSHLHTPMFFFLSHLALTDISLSSVTVPKMLLSMQTQDQSILYAGCVTQMYFFIFFTDLDNFLLTSMAYDRYVAICHP---------LRYTTIMKEGLCNLLVTVSWILSCTNALSHTLLLAQLSFCADNTIPHFFCDLVALLKLSCSDISLNELVIFTVGQAVITLPLICILISYGHIGVTILK-APSTKGIFKALSTCGSHLSVVS--LYYGTIIGLYFLP--SSSASS---DKDVIASVMYTVITPLLNPFIYSLRNRDIKGALERLFNRATVLSQ------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH92-1", "uniprot_id": "OR1S1_HUMAN", "id": "Q8NH92-1", "name": "Olfactory receptor 1S1", "aln": "-------------------MKTFS-----SFLQIGRNMHQ---GNQTTITEFILLGFFKQDEHQNLLFVLFLGMYLVTVIGNGLIIVAISLDTYLHTPMYLFLANLSFADISSISNSVPKMLVNIQTKSQSISYESCITQMYFSIVFVVIDNLLLGTMAYDHFVAICHP---------LNYTILMRPRFGILLTVISWFLSNIIALTHTLLLIQLLFCNHNTLPHFFCDLAPLLKLSCSDTLINELVLFIVGLSVIIFPFTLSFFSYVCIIRAVLR-VSSTQGKWKAFSTCGSHLTVVL--LFYGTIVGVYFFP--SSTHPED---TDKIGAVLFTVVTPMINPFIYSLRNKDMKGALRKLINRKISSL-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGQ3-1", "uniprot_id": "OR1S2_HUMAN", "id": "Q8NGQ3-1", "name": "Olfactory receptor 1S2", "aln": "-------------------MKTLC-----SFLQISRNMHQ---ENQTTITEFILLGLSNQAEHQNLLFVLFLSMYVVTVVGNGLIIVAISLDIYLHTPMYLFLAYLSFADISSISNSVPKMLVNIQTNSQSISYESCITQMYFSIVFVVTDNLLLGTMAFDHFVAICHP---------LNYTTFMRARFGTLLTVISWFLSNIIALTHTLLLIQLLFCDHNTLPHFFCDLAPLLKLSCSDTMINELVLFIVGLSVIIFPFVLIFFSYVCIIRAVLG-VSSTQGKWKAFSTCGSHLTIAL--LFYGTTVGVYFFP--SSTHPED---TDKIGAVLFTVVTPMMNPFIYSLRNKDMKGALRKLINRKISSL-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1LV45-1", "uniprot_id": "F1LV45_RAT", "id": "F1LV45-1", "name": "Olfactory receptor", "aln": "-----------------------------------RNMSQ---GNQTTISEFILLGLSNQAEKQKFIFVIFLSMYLVTVLGNSLIILVIGLDVNLHTPMYLFLANLSFADISSSSTSVPKMLMNIQTKSQYISYEGCFTQMYFSIVFVVIDNFLLGVMAYDRYVAICHP---------LTYTSIMHSTFCLLLTVCPWALSNIVALTHTLLANQLIFCNDNTIQHFFCDLAPLLKLSCSDAMINNIVKFIVGLSVITFPFALILFSYVCIIRDVLR-ISSMEGKWKAFSTCGSHLTVVF--LFYGTIIGVYFFP--LSTHPED---TDKIGAVLFTVVTPMLNPFIYSLRNKDMKGAFKKLINKSHFFLLMS----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEU7-1", "uniprot_id": "Q8VEU7_MOUSE", "id": "Q8VEU7-1", "name": "Olfactory receptor", "aln": "-------------------MLPFNDEDEFSLFRYSRTMHQ---GNQTAISGFILLGLTVGSEQQLLLFTLFLCMYLVTMVGNSLIILAIISDTHLYSPMYFFLANLSFTDICFTTTTVPKILADIQSQNPTISFVGCFTQMYFFMFLVDLDNFLLAAMAYDRYIAICHP---------LHYAALLNPKRCALLVVVPWVISNLVSVLHLSLLSRLPFCDQRVIPHFFCDLEPVLRLACSDTQINNLLILIVGGTVIFVPFVFILVSYALIGTAVLN-VPSVKGKWKTFSTCGSHLSAVS--LFYGSIVGVYFLP--ASSYSAE---RDKVAAIMYTVVTPMMNPFIYSLRNKDMKRALRRLLSQKSLICSW-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A4S6-1", "uniprot_id": "D4A4S6_RAT", "id": "D4A4S6-1", "name": "", "aln": "-------------------------------------MAV---TNLTYRPQFQLLGLMDGADTHPLLFLLFLSIYLLNALGNLSMVVLVRSDGALCSPMYYFLGHLSLVDVCFTTVTVPRLLVTLLHPGQAMSFQDCFAQMYFFVALGITESYLLAAMSYDRVVAVCRP---------LHYGVVMTPWRCFVLVAASWTVAHLHSLLHTLLISALSYPRSAPVHHFFCDMTVMLSLATSDTSTAETAIFSEGLAVVLTPLILVSLSYARILVAVLG-MQTTGGRHRVFSTCGAHLVVVS--LFFGSVLSVYFRP--SFGYSAR---YDRMASVVYAVVTPTLNPFIYSLRNKEVKGALKRGFRWRAAAQDE-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VFY0-1", "uniprot_id": "Q8VFY0_MOUSE", "id": "Q8VFY0-1", "name": "", "aln": "-------------------------------------MAV---TNLTYKPQFQLLGLMDGTDPHPLLFLLFLSIYLLNALGNLSMVVLVRSDGALCSPMYYFLGHLSLVDVCFTTVTVPRLLATLLHPGQAISFQACFAQMYFFVALGITESYLLAAMSYDRAVAVCRP---------LHYGAVMTPWRCFLLVAASWAVAHLHSLLHTLLISALTYPPSAPVRHFFCDMTVMLSLATSDTSAAETAIFSEGLTVVLTPLLLVSLSYARILVAVLG-IRTTGGRHRVFSTCGAHLVVVS--LFFGSVLSVYFRP--SSAYSAR---YDRMASVVYAVVTPTLNPFIYSLRNKEVKSALKRGFRWRAAPQDE-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A286YEU6-1", "uniprot_id": "OR1R1_HUMAN", "id": "A0A286YEU6-1", "name": "Olfactory receptor 1R1", "aln": "-------------------------------------MAP---TNLTSAPVFLLLGLVDGTDAHPLLFLLCLGIYLLNALSNLSMVALVRSDGALRSPMYYFLGHLSLVDVCFTTVTVPRLLAGLLHPGQAISFQACFAEMYFFVALGITESYLLAAMSYDRPTAACRP---------LRYGALVTPWRCASLVRASWAVTHLHSLLHTLLLSALSYPYPTPVRPFFCDMTVMLSLATSDTSAAETAIFSEGLAVVLAPLLLVFLFLR--AHPGRG-ARLAGGRRRAFSTCGAHLVAVAVALFFGSVLSVYFPP--SSAYSAR---YDRLASVVYAVITPTLNPFINSLRNKEVKGALKRGLRWRAAPQEA-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGR2-1", "uniprot_id": "OR1L6_HUMAN", "id": "Q8NGR2-1", "name": "Olfactory receptor 1L6", "aln": "MSYFYRLKLMKEAVLVKLPFTSLPLLLQTLSRKSRDMEIK---NYSSSTSGFILLGLSSNPQLQKPLFAIFLIMYLLAAVGNVLIIPAIYSDPRLHTPMYFFLSNLSFMDICFTTVIVPKMLVNFLSETKVISYVGCLAQMYFFMAFGNTDSYLLASMAIDRLVAICNP---------LHYDVVMKPRHCLLMLLGSCSISHLHSLFRVLLMSRLSFCASHIIKHFFCDTQPVLKLSCSDTSSSQMVVMTETLAVIVTPFLCIIFSYLRIMVTVLR-IPSAAGKWKAFSTCGSHLTAVA--LFYGSIIYVYFRP--LSMYSVV---RDRVATVMYTVVTPMLNPFIYSLRNKDMKRGLKK-LQDRIYR--------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TRY4-1", "uniprot_id": "Q7TRY4_MOUSE", "id": "Q7TRY4-1", "name": "Olfactory receptor", "aln": "-------------------------------------MLR---ENQSHMTEFLLLGLTSNPKQQVWLFASFLAMYLVNVIGNSVIIASIQRDARLHTPMYFFLSNLSLVDICFTTVIVPQMLVNLLTQRKTILFAQCLTQMYFFVAFGITDSFLLAAMAIDRYVAICNP---------LHYNTVMSPRRCRLLVVASWAVSHLHSLTHTILMGRLSFCGPNVIHHFFCDVQPLLTLSCSDTSINELLAFTEGSVVIMSPFIFIVVSYIYITRTVLR-VPSGEGRYKVFSTCGSHLTVVA--LFYGTIISVYIRP--SSTYSVT---KDRVVTVIYTVVTPMLNPFIYSLRNKDMKQALRK-LAKRTE---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LNM5-1", "uniprot_id": "A0ABK0LNM5_RAT", "id": "A0ABK0LNM5-1", "name": "", "aln": "-------------------------------------MAP---VNQSVVTMFILQNFVDDPWIQDVLFCLFFALFMMAIAGNGLIIMTIYSSANLHTPMYFFLVNLSLMDVICTVTVLPKVLQSLVA-ENAISYGGCLTQMFVFSWVLGSELLLFSAMAYDRYLAICRP---------LHYGTLMNGRACVALATFVWFTGALNSLVLTCLVLPLSFCGPNLITHFFCEIPSVLMLSCSSTFINDIMTVITDMFLTGLNFLLTMTSYVFIIASILR-IRSAEGKKRAFSTCSAHLVVVT--LYYSTVLYTYVRP--ALGTAGL---LDKAVAVLYTTVTPSLNPLIYTLRNKEFKTSFKKLLFPH-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6B0Y0-1", "uniprot_id": "A0A8I6B0Y0_RAT", "id": "A0A8I6B0Y0-1", "name": "", "aln": "-------------------------------------MAP---INQSVVTMFFLQNFVDDPWIQNVLFCFFFALFVAAIAGNGLIITVIHSSANLHTPMYFFLVNLSLMDVICTVTVLPKVLQSLVA-ENAISYGGCLTQMFVFSWVLGSELLLFSAMAYDRYLAICRP---------LHYGTLMSGRVCIALATFVWFTGALNSLVLTCLVLPLSFCGPNLITHFFCEIPSVLMLSCSPTFINDIMTVIADMFLTGLNFLLTMTSYGFIIASILR-IRSAEGKKRAFSTCSAHLVVVT--LYYSTVLYTYVRP--ALGTSGL---LDKVIAVLYTTVTPSLNPLIYTLRNKEFKTSFKKLLFPN-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2K0L2-1", "uniprot_id": "A0A0G2K0L2_RAT", "id": "A0A0G2K0L2-1", "name": "", "aln": "-------------------------------------------MNGTLVTEFLILGFSEMPHLRVP-LLSFLCLYMAAISGNLLIMVTVSASPALHTPMYFFLVNLAVVDILCTSTILPKLLDIMVG-GRTISYGGCMAQLFFFTWSMGAELLLFSAMAYDRFVAICCP---------LHYSTWMGPRVCAFLAGLVWSISLTNTSVNTSLVLHLPFCSSNVIEHFFCEIPPLLKLSCAPTQLNEVMAFAADVFLAVGNFSVIILSYGFIVTSILK-IRSTEGKQRAFSTCSAHLFVVT--MYYSTIIYTYIRP--ASSYSLN---KDKVVSIIYTSVAPTLNPLIYTLRNKDVKVALRKLLSSC-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TRT9-1", "uniprot_id": "Q7TRT9_MOUSE", "id": "Q7TRT9-1", "name": "", "aln": "---------------------------------------M---MNGTLVTEFLILGFSEMPHLRVPLLFSFLCLYMAAISGNLLIMVTISASPALHTPMYFFLVNLAIVDILCTSTILPKLLDSMMT-GRTISYGGCMAQLFFFTWSLGAELLLFSAMAYDRFVAICCP---------LHYSAWMGPRVCAFLAGIVWTISLTNTSVHTGLMLRLPFCSSNVIEHFFCEIPPLLKLSCAPTQLNEAMAFAADVFLAVGNFSVTILSYGFIVASILK-IRSAEGKRRAFSTCSAHLIVVT--MYYSTVIYTYIRP--SSSYSLN---KDKVVSIIYTSVAPTLNPLIYTLRNKDVKVALRRLLSCC-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGL2-1", "uniprot_id": "Q8VGL2_MOUSE", "id": "Q8VGL2-1", "name": "", "aln": "-------------------------------------------MNGTLVTEFLILGFSDMPHLRILLFLSFLCLYMAAVSGNLLIMVTISASPTLHTPMYFFLVNLAVVDILCTSTILPKLLDTMVG-GRTISYGGCMAQLFFFTWSLGVELLLFSAMAYDRFVAICCP---------LHYSTWMGPRVCAFLAGIVWAISLTNTSINSSLVLRLPFCSSNVVEHFFCEIPPLLKLSCAPTQLNEAMAFAADVFLAVGNFSVIILSYGFIVASILK-IRSAEGKQRAFSTCSAHLIVVT--MYYSTVIYTYIRP--SSSYSLN---KDKVVSIIYTSVAPTLNPLIYTLRNKDVKVALRRLFSCC-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TS01-1", "uniprot_id": "Q7TS01_MOUSE", "id": "Q7TS01-1", "name": "", "aln": "---------------------------------------M---MNFSIVSEFMILGLTQKSELQGILFIVFLFIYLVALLGNMLIVVAIIYNTTLHTPMYILLLALAVVDIICTTSIIPKMLGTMLTSKNSISYGGCMSQLFFFTWSLGAEMVLFTTMAYDRYVAICFP---------LRYSTIMNHYTCVGLLSIVMAIAVTNSWVHTGLILRLTFCGPNIIDHFFCEIPPLLALSCSPVRVNEVMVYVADITLAVGDFTLTCISYGFIIAAILR-IRTTEGKKKAFSTCSSHLMVVS--LYYSPVIYTYIRP--ASSYTFD---KDKVVAALYTLVTPTLNPIVYSFRNKEMQSGIKKVFAFLKG---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGZ3-1", "uniprot_id": "O13G1_HUMAN", "id": "Q8NGZ3-1", "name": "Olfactory receptor 13G1", "aln": "-------------------------------------------MNHSVVTEFIILGLTKKPELQGIIFLFFLIVYLVAFLGNMLIIIAKIYNNTLHTPMYVFLLTLAVVDIICTTSIIPKMLGTMLTSENTISYAGCMSQLFLFTWSLGAEMVLFTTMAYDRYVAICFP---------LHYSTIMNHHMCVALLSMVMAIAVTNSWVHTALIMRLTFCGPNTIDHFFCEIPPLLALSCSPVRINEVMVYVADITLAIGDFILTCISYGFIIVAILR-IRTVEGKRKAFSTCSSHLTVVT--LYYSPVIYTYIRP--ASSYTFE---RDKVVAALYTLVTPTLNPMVYSFQNREMQAGIRKVFAFLKH---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A8W9-1", "uniprot_id": "A0AB13A8W9_DANRE", "id": "A0AB13A8W9-1", "name": "", "aln": "---------------------------------MSSLNASSYKNTSIVHPEYFFISGLSGIPYSSYYYVFLFITYFITIIGNSVVLLIIAFERSLHSPKYIVVFNLALADIGETNALIPNMMKTFLFDSQYISYNACLVNMFFVFLFSTMQSFTLVVLAYDRFVAICLP---------LRYHAIVNNSSITLILSAKWAFNSSMVALMVSLITRISFCDSNVIQSYFCDHGPVYRLACNDNSINRFMGSFITCLYLVVPLAIIILSYIGIFLALNK-ITTWESRLKALKTCVSHLLLVG--IYFLPMSCTYIAAWLLALAPNAR----VITTSLAYTISPMLNPIIYVLNTAEIKDLLRKMFKNKSAPSKDNIAK-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : .* :. * : : :: : . : : *. : . : :: . * * : : : : : : :: :.:.** *: : * : . ..*:: :.. :. . ", "identical_positions": 10, "similar_positions": 47, "identity": "2.43%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000329-13", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IF42-1", "uniprot_id": "OR2A2_HUMAN", "id": "Q6IF42-1", "name": "Olfactory receptor 2A2", "aln": "--------------------------------------------------ME-GNQTW---ITDITLLGFQVGPA-LAILLCGLFSVFYTLTLLGNGVIFGIICLDSK-LHTPMYFFLSHLAIIDMSYASNNVPKMLANLMNQKRTISFVPCIMQTFLYLAFAVTECLILVVMSYDRYVAICHPFQYTVIMSWRVCTILVLTSWSCGFALSLVHEILLLRLPFCGPRDVNHLFCEILSVLKLACADTWVNQVVIFATCVFVLVGPLSLILVSYMHILGAILKIQTKEGRIKAFSTCSSHLCVVGLFFGIAMVVYMVPDS--NQREEQEKMLSLFHSVFNPMLNPLIYS------------------LRNAQLK-----------GALHRALQ--------RKRSMRTVYGLCL-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96R47-1", "uniprot_id": "O2A14_HUMAN", "id": "Q96R47-1", "name": "Olfactory receptor 2A14", "aln": "--------------------------------------------------ME-GNKTW---ITDITLPRFQVGPA-LEILLCGLFSAFYTLTLLGNGVIFGIICLDCK-LHTPMYFFLSHLAIVDISYASNYVPKMLTNLMNQESTISFFPCIMQTFLYLAFAHVECLILVVMSYDRYADICHPLRYNSLMSWRVCTVLAVASWVFSFLLALVPLVLILSLPFCGPHEINHFFCEILSVLKLACADTWLNQVVIFAACVFILVGPLCLVLVSYLRILAAILRIQSGEGRRKAFSTCSSHLCVVGLFFGSAIVTYMAPKS--RHPEEQQKVLSLFYSLFNPMLNPLIYS------------------LRNAEVK-----------GALRRALR--------KERLT-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGT9-1", "uniprot_id": "OR2A1_HUMAN", "id": "Q8NGT9-1", "name": "Olfactory receptor 2A1/2A42", "aln": "--------------------------------------------------MG-ENQTM---VTEFLLLGFLLGPR-IQMLLFGLFSLFYIFTLLGNGAILGLISLDSR-LHTPMYFFLSHLAVVDIAYTRNTVPQMLANLLHPAKPISFAGCMTQTFLCLSFGHSECLLLVLMSYDRYVAICHPLRYSVIMTWRVCITLAVTSWTCGSLLALAHVVLILRLPFSGPHEINHFFCEILSVLRLACADTWLNQVVIFAACVFFLVGPPSLVLVSYSHILAAILRIQSGEGRRKAFSTCSSHLCVVGLFFGSAIIMYMAPKS--RHPEEQQKVFFLFYSFFNPTLNPLIYS------------------LRNGEVK-----------GALRRALG--------KESHS-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGY7-1", "uniprot_id": "O10J6_HUMAN", "id": "Q8NGY7-1", "name": "Putative olfactory receptor 10J6", "aln": "--------------------------------------------------MRRKNLTE---VTEFVFLGFSRFHK-HHITLFVVFLILYTLTVAGNAIIMTIICIDRH-LHTPMYFFLSMLASSKTVYTLFIIPQMLSSFVTQTQPISLAGCTTQTFFFVTLAINNCFLLTVMGYDHYMAICNPLRYRVITSKKVCVQLVCGAFSIGLAMAAVQVTSIFTLPFCHT-VVGHFFCDILPVMKLSCINTTINEIINFVVRLFVILVPMGLVFISYVLIISTVLKIASAEGWKKTFATCAFHLTVVIVHYGCASIAYLMPKS--ENSIEQDLLLSVT------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47893-1", "uniprot_id": "OR3A2_HUMAN", "id": "P47893-1", "name": "Olfactory receptor 3A2", "aln": "--------------------------------------------MSLQKLMEPEAGTNRTAVAEFILLGLVQTEE-MQPVVFVLLLFAYLVTTGGNLSILAAVLVEPK-LHAPMYFFLGNLSVLDVGCITVTVPAMLGRLLSHKSTISYDACLSQLFFFHLLAGMDCFLLTAMAYDRLLAICQPLTYSTRMSQTVQRMLVAASLACAFTNALTHTVAMSTLNFCGPNEVNHFYCDLPQLFQLSCSSTQLNELLLFAVGFIMAGTPLVLIITAYSHVAAAVLRIRSVEGRKKAFSTCGSHLTVVCLFFGRGIFNYMRLGS--EEASDKDKGVGVFNTVINPMLNPLIYS------------------LRNPDVQ-----------GALWQIFL--------GRRSLT------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47888-1", "uniprot_id": "OR3A3_HUMAN", "id": "P47888-1", "name": "Olfactory receptor 3A3", "aln": "--------------------------------------------MSLQKLMEPEAGTNRTAVAEFILLGLVQTEE-MQPVVFVLLLFAYLVTTGGNLSILAAVLVEPK-LHAPMYFFLGNLSVLDVGCITVTVPAMLGRLLSHKSTISYDACLSQLFFFHLLAGMDCFLLTAMAYDRLLAICQPLTYSTRMSQTVQRMLVAASWACAFTNALTHTVAMSTLNFCGPNEVNHFYCDLPQLFQLSCSSTQLNELLLFVAAAFMAVAPLVFISVSYAHVVAAVLQIRSAEGRKKAFSTCGSHLTVVGIFYGTGVFSYMRLGS--VESSDKDKGVGVFMTVINPMLNPLIYS------------------LRNTDVQ-----------GALCQLLV--------GKRSLT------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47881-1", "uniprot_id": "OR3A1_HUMAN", "id": "P47881-1", "name": "Olfactory receptor 3A1", "aln": "--------------------------------------------------MQPESGANGTVIAEFILLGLLEAPG-LQPVVFVLFLFAYLVTVRGNLSILAAVLVEPK-LHTPMYFFLGNLSVLDVGCISVTVPSMLSRLLSRKRAVPCGACLTQLFFFHLFVGVDCFLLTAMAYDRFLAICRPLTYSTRMSQTVQRMLVAASWACAFTNALTHTVAMSTLNFCGPNVINHFYCDLPQLFQLSCSSTQLNELLLFAVGFIMAGTPMALIVISYIHVAAAVLRIRSVEGRKKAFSTCGSHLTVVAIFYGSGIFNYMRLGS--TKLSDKDKAVGIFNTVINPMLNPIIYS------------------FRNPDVQ-----------SAIWRMLT--------GRRSLA------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47883-1", "uniprot_id": "OR3A4_HUMAN", "id": "P47883-1", "name": "Putative olfactory receptor 3A4", "aln": "--------------------------------------------------MDLGNSGNDSVVTKFVLLGLTETAA-LQPILFVIFLLAYVTTIGGTLSILAAILMETK-LHSPMYFFLGNLSLPDVGCVSVTVPAMLSHFISNDRSIPYKACLSELFFFHLLAGADCFLLTIMAYDRYLAICQSLTYSSRMSWGIQQALVGMSCVFSFTNALTQTVALSPLNFCGPNVINHFYCDLPQPFQLSCSSVHLNGQLLFVAAAFMGVAPLVLITVSYAHVAAAVLRIRSAEGRKKAFSTCSSHLTVVGIFYGTGVFSYTRLGS--VESSDKDKGIGILNTVISPMLNPLIYWTSLLDVGCISHCSSDAGVSPGPPVQ-----------SSLCCLQFTALLSPPPGWGGLSPLNSHGL-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH94-1", "uniprot_id": "OR1L1_HUMAN", "id": "Q8NH94-1", "name": "Olfactory receptor 1L1", "aln": "MERNHNPDNCNVLNFFFADKKNKRRNFGQIVSDVGRICYSVSLSLGEPTTMGRNNLTR---PSEFILLGLSSRPE-DQKPLFAVFLPIYLITVIGNLLIILAIRSDTR-LQTPMYFFLSILSFVDICYVTVIIPKMLVNFLSETKTISYSECLTQMYFFLAFGNTDSYLLAAMAIDRYVAICNPFHYITIMSHRCCVLLLVLSFCIPHFHSLLHILLTNQLIFCASNVIHHFFCDDQPVLKLSCSSHFVKEITVMTEGLAVIMTPFSCIIISYLRILITVLKIPSAAGKRKAFSTCGSHLTVVTLFYGSISYLYFQPLS--NYTV-KDQIATIIYTVLTPMLNPFIYS------------------LRNKDMK-----------QGLAKLMH--------RMKCQ-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH93-1", "uniprot_id": "OR1L3_HUMAN", "id": "Q8NH93-1", "name": "Olfactory receptor 1L3", "aln": "--------------------------------------------------MGMSNLTR---LSEFILLGLSSRSE-DQRPLFALFLIIYLVTLMGNLLIILAIHSDPR-LQNPMYFFLSILSFADICYTTVIVPKMLVNFLSEKKTISYAECLAQMYFFLVFGNIDSYLLAAMAINRCVAICNPFHYVTVMNRRCCVLLLAFPITFSYFHSLLHVLLVNRLTFCTSNVIHHFFCDVNPVLKLSCSSTFVNEIVAMTEGLASVMAPFVCIIISYLRILIAVLKIPSAAGKHKAFSTCSSHLTVVILFYGSISYVYLQPLS--SYTV-KDRIATINYTVLTSVLNPFIYS------------------LRNKDMK-----------RGLQKLIN--------KIKSQMSRFSTKTNKICGP-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGR8-1", "uniprot_id": "OR1L8_HUMAN", "id": "Q8NGR8-1", "name": "Olfactory receptor 1L8", "aln": "--------------------------------------------------MERINHTSS--VSEFILLGLSSRPE-DQKTLFVLFLIVYLVTITGNLLIILAIRFNPH-LQTPMYFFLSFLSLTDICFTTSVVPKMLMNFLSEKKTISYAGCLTQMYFLYALGNSDSCLLAVMAFDRYVAVCDPFHYVTTMSHHHCVLLVAFSCSFPHLHSLLHTLLLNRLTFCDSNVIHHFLCDLSPVLKLSCSSIFVNEIVQMTEAPIVLVTRFLCIAFSYIRILTTVLKIPSTSGKRKAFSTCGFYLTVVTLFYGSIFCVYLQPPS--TYAV-KDHVATIVYTVLSSMLNPFIYS------------------LRNKDLK-----------QGLRKLMS--------KRS---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q15612-1", "uniprot_id": "OR1Q1_HUMAN", "id": "Q15612-1", "name": "Olfactory receptor 1Q1", "aln": "--------------------------------------------------MDNSNWTS---VSHFVLLGISTHPE-EQIPLFLVFSLMYAINISGNLAIITLILSAPR-LHIPMYIFLSNLALTDICFTSTTVPKMLQIIFSPTKVISYTGCLAQTYFFICFAVMENFILAVMAYDRYIAICHPFHYTMILTRMLCVKMVVMCHALSHLHAMLHTFLIGQLIFCADNRIPHFFCDLYALMKISCTSTYLNTLMIHTEGAVVISGALAFITASYACIILVVLRIPSAKGRWKTFSTCGSHLTVVAIFYGTLSWVYFRPLS--SYSVTKGRIITVVYTVVTPMLNPFIYS------------------LRNGDVK-----------GGFMKWMS--------RMQTFFFR----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y585-1", "uniprot_id": "OR1A2_HUMAN", "id": "Q9Y585-1", "name": "Olfactory receptor 1A2", "aln": "--------------------------------------------------MKKENQSF---NLDFILLGVTSQQE-QNNVFFVIFLCIYPITLTGNLLIILAICADIR-LHNPMYFLLANLSLVDIIFSSVTIPKVLANHLLGSKFISFGGCLMQMYFMIALAKADSYTLAAMAYDRAVAISCPLHYTTIMSPRSCILLIAGSWVIGNTSALPHTLLTASLSFCGNQEVANFYCDIMPLLKLSCSDVH-FNVKMMYLGVGVFSLPLLCIIVSYVQVFSTVFQVPSTKSLFKAFCTCGSHLTVVFLYYGTTMGMYFRPLT--SYSP-KDAVITVMYVAVTPALNPFIYS------------------LRNWDMK-----------AALQKLFS--------KRISS-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9P1Q5-1", "uniprot_id": "OR1A1_HUMAN", "id": "Q9P1Q5-1", "name": "Olfactory receptor 1A1", "aln": "--------------------------------------------------MRENNQSS---TLEFILLGVTGQQE-QEDFFYILFLFIYPITLIGNLLIVLAICSDVR-LHNPMYFLLANLSLVDIFFSSVTIPKMLANHLLGSKSISFGGCLTQMYFMIALGNTDSYILAAMAYDRAVAISRPLHYTTIMSPRSCIWLIAGSWVIGNANALPHTLLTASLSFCGNQEVANFYCDITPLLKLSCSDIH-FHVKMMYLGVGIFSVPLLCIIVSYIRVFSTVFQVPSTKGVLKAFSTCGSHLTVVSLYYGTVMGTYFRPLT--NYSL-KDAVITVMYTAVTPMLNPFIYS------------------LRNRDMK-----------AALRKLFN--------KRISS-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47884-1", "uniprot_id": "OR1D4_HUMAN", "id": "P47884-1", "name": "Olfactory receptor 1D4", "aln": "--------------------------------------------------MDGDNQSE---NSQFLLLGISESPE-QQQILFWMFLSMYLVTVLGNVLIILAISSDSH-LHTPMYFFLANLSFTDLFFVTNTIPKMLVNFQSQNKAISYAGCLTQLYFLVSLVTLDNLILAVMAYDRYVAICCPLHYVTAMSPGLCVLLLSLCWGLSVLYGLLLTFLLTRVTFCGPREIHYLFCDMYILLWLACSNTHIIHTALIATGCFIFLTLLGFMTTSYVRIVRTILQMPSASKKYKTFSTCASHLGVVSLFYGTLAMVYLQPLH--TYSM-KDSVATVMYAVLTPMMNPFIYS------------------LRNKDMH-----------GAPGRVLW--------RPFQRP------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P58170-1", "uniprot_id": "OR1D5_HUMAN", "id": "P58170-1", "name": "Olfactory receptor 1D5", "aln": "--------------------------------------------------MDGDNQSE---NSQFLLLGISESPE-QQRILFWMFLSMYLVTVLGNVLIILAISSDSH-LHTPMYFFLANLSFTDLFFVTNTIPKMLVNFQSQNKAISYAGCLTQLYFLVSLVTLDNLILAVMAYDRYVATCCPLHYVTAMSPGLCVLLLSLCWGLSVLYGLLLTFLLTRVTFCGPREIHYLFCDMYILLWLACSNTHIIHTALIATGCFIFLTPLGFMTTSYVRIVRTILQMPSASKKYKTFSTCASHLGVVSLFYGTLAMVYLQPLH--TYSM-KDSVATVMYAVLTPMMNPFIYR------------------LRNKDMH-----------GAPGRVLW--------RPFQRPK-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGB8-1", "uniprot_id": "O4F15_HUMAN", "id": "Q8NGB8-1", "name": "Olfactory receptor 4F15", "aln": "--------------------------------------------------MNGMNHSV---VSEFVFMGLTNSRE-IQLLLFVFSLLFYFASMMGNLVIVFTVTMDAH-LHSPMYFLLANLSIIDMAFCSITAPKMICDIFKKHKAISFRGCITQIFFSHALGGTEMVLLIAMAFDRYMAICKPLHYLTIMSPRMCLYFLATSSIIGLIHSLVQLVFVVDLPFCGPNIFDSFYCDLPRLLRLACTNTQELEFMVTVNSGLISVGSFVLLVISYI-FILFTVWKHSSGGLAKALSTLSAHVTVVILFFGPLMFFYTWPSP--TSHL--DKYLAIFDAFITPFLNPVIYT------------------FRNKDMK-----------VAMRRLCS--------RLAHFTKIL---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGB9-1", "uniprot_id": "OR4F6_HUMAN", "id": "Q8NGB9-1", "name": "Olfactory receptor 4F6", "aln": "--------------------------------------------------MDEANHSV---VSEFVFLGLSDSRK-IQLLLFLFFSVFYVSSLMGNLLIVLTVTSDPR-LQSPMYFLLANLSIINLVFCSSTAPKMIYDLFRKHKTISFGGCVVQIFFIHAVGGTEMVLLIAMAFDRYVAICKPLHYLTIMNPQRCILFLVISWIIGIIHSVIQLAFVVDLLFCGPNELDSFFCDLPRFIKLACIETYTLGFMVTANSGFISLASFLILIISYI-FILVTVQKKSSGGIFKAFSMLSAHVIVVVLVFGPLIFFYIFPFP--TSHL--DKFLAIFDAVITPVLNPVIYT------------------FRNKEMM-----------VAMRRRCS--------QFVNYSKIF---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH21-1", "uniprot_id": "OR4F5_HUMAN", "id": "Q8NH21-1", "name": "Olfactory receptor 4F5", "aln": "---------------------------------------------------------M---VTEFIFLGLSDSQE-LQTFLFMLFFVFYGGIVFGNLLIVITVVSDSH-LHSPMYFLLANLSLIDLSLSSVTAPKMITDFFSQRKVISFKGCLVQIFLLHFFGGSEMVILIAMGFDRYIAICKPLHYTTIMCGNACVGIMAVTWGIGFLHSVSQLAFAVHLLFCGPNEVDSFYCDLPRVIKLACTDTYRLDIMVIANSGVLTVCSFVLLIISYT-IILMTIQHRPLDKSSKALSTLTAHITVVLLFFGPCVFIYAWPFP--IKSL--DKFLAVFYSVITPLLNPIIYT------------------LRNKDMK-----------TAIRQLRK--------WDAHSSVKF---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGD3-1", "uniprot_id": "OR4K5_HUMAN", "id": "Q8NGD3-1", "name": "Olfactory receptor 4K5", "aln": "--------------------------------------------------MDKSNSSV---VSEFVLLGLCSSQK-LQLFYFCFFSVLYTVIVLGNLLIILTVTSDTS-LHSPMYFLLGNLSFVDICQASFATPKMIADFLSAHETISFSGCIAQIFFIHLFTGGEMVLLVSMAYDRYVAICKPLYYVVIMSRRTCTVLVMISWAVSLVHTLSQLSFTVNLPFCGPNVVDSFFCDLPRVTKLACLDSYIIEILIVVNSGILSLSTFSLLVSSYI-IILVTVWLKSSAAMAKAFSTLASHIAVVILFFGPCIFIYVWPFT--ISPL--DKFLAIFYTVFTPVLNPIIYT------------------LRNRDMK-----------AAVRKIVN--------HYLRPRRISEMSLVVRTSFH----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGC6-1", "uniprot_id": "OR4KH_HUMAN", "id": "Q8NGC6-1", "name": "Olfactory receptor 4K17", "aln": "--------------------------------------------------MKLLNQSQ---VSEFILLGLTSSQD-VEFLLFALFSVIYVVTVLGNLLIIVTVFNTPN-LNTPMYFLLGNLSFVDMTLASFATPKVILNLLKKQKVISFAGCFTQIFLLHLLGGVEMVLLVSMAFDRYVAICKPLHYMTIMNKKVCVLLVVTSWLLGLLHSGFQIPFAVNLPFCGPNVVDSIFCDLPLVTKLACIDIYFVQVVIVANSGIISLSCFIILLISYS-LILITIKNHSPTGQSKARSTLTAHITVVILFFGPCIFIYIWPFG--NHSV--DKFLAVFYTIITPILNPIIYT------------------LRNKEMK-----------ISMKKLWR--------AFVNSREDT---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH42-1", "uniprot_id": "OR4KD_HUMAN", "id": "Q8NH42-1", "name": "Olfactory receptor 4K13", "aln": "--------------------------------------------------MERANHSV---VSEFILLGLSKSQN-LQILFFLGFSVVFVGIVLGNLLILVTVTFDSL-LHTPMYFLLSNLSCIDMILASFATPKMIVDFLRERKTISWWGCYSQMFFMHLLGGSEMMLLVAMAIDRYVAICKPLHYMTIMSPRVLTGLLLSSYAVGFVHSSSQMAFMLTLPFCGPNVIDSFFCDLPLVIKLACKDTYILQLLVIADSGLLSLVCFLLLLVSYG-VIIFSVRYRAASRSSKAFSTLSAHITVVTLFFAPCVFIYVWPFS--RYSV--DKILSVFYTIFTPLLNPIIYT------------------LRNQEVK-----------AAIKKRLC--------I-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH43-1", "uniprot_id": "OR4L1_HUMAN", "id": "Q8NH43-1", "name": "Olfactory receptor 4L1", "aln": "--------------------------------------------------MDLKNGSL---VTEFILLGFFGRWE-LQIFFFVTFSLIYGATVMGNILIMVTVTCRST-LHSPLYFLLGNLSFLDMCLSTATTPKMIIDLLTDHKTISVWGCVTQMFFMHFFGGAEMTLLIIMAFDRYVAICKPLHYRTIMSHKLLKGFAILSWIIGFLHSISQIVLTMNLPFCGHNVINNIFCDLPLVIKLACIETYTLELFVIADSGLLSFTCFILLLVSYI-VILVSVPKKSSHGLSKALSTLSAHIIVVTLFFGPCIFIYVWPFS--SLAS--NKTLAVFYTVITPLLNPSIYT------------------LRNKKMQ-----------EAIRKLRF--------QYVSSAQNF---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGD2-1", "uniprot_id": "OR4K2_HUMAN", "id": "Q8NGD2-1", "name": "Olfactory receptor 4K2", "aln": "--------------------------------------------------MDVGNKST---MSEFVLLGLSNSWE-LQMFFFMVFSLLYVATMVGNSLIVITVIVDPH-LHSPMYFLLTNLSIIDMSLASFATPKMITDYLTGHKTISFDGCLTQIFFLHLFTGTEIILLMAMSFDRYIAICKPLHYASVISPQVCVALVVASWIMGVMHSMSQVIFALTLPFCGPYEVDSFFCDLPVVFQLACVDTYVLGLFMISTSGIIALSCFIVLFNSYV-IVLVTVKHHSSRGSSKALSTCTAHFIVVFLFFGPCIFIYMWPLS--SFLT--DKILSVFYTIFTPTLNPIIYT------------------LRNQEVK-----------IAMRKLKN--------RFLNFNKAMPS-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q15615-1", "uniprot_id": "OR4D1_HUMAN", "id": "Q15615-1", "name": "Olfactory receptor 4D1", "aln": "--------------------------------------------------MEPQNTTQ---VSMFVLLGFSQTQE-LQKFLFLLFLLVYVTTIVGNLLIMVTVTFDCR-LHTPMYFLLRNLALIDLCYSTVTSPKMLVDFLHETKTISYQGCMAQIFFFHLLGGGTVFFLSVMAYDRYIAISQPLRYVTIMNTQLCVGLVVAAWVGGFVHSIVQLALILPLPFCGPNILDNFYCDVPQVLRLACTDTSLLEFLMISNSGLLVIIWFLLLLISYT-VILVMLRSHSGKARRKAASTCTTHIIVVSMIFIPCIYIYTWPFT--PFLM--DKAVSISYTVMTPMLNPMIYT------------------LRNQDMK-----------AAMRRLGK--------CLVICRE-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGJ1-1", "uniprot_id": "OR4D6_HUMAN", "id": "Q8NGJ1-1", "name": "Olfactory receptor 4D6", "aln": "--------------------------------------------------MDQINHTN---VKEFFFLELTRSRE-LEFFLFVVFFAVYVATVLGNALIVVTITCESR-LHTPMYFLLRNKSVLDIVFSSITVPKFLVDLLSDRKTISYNDCMAQIFFFHFAGGADIFFLSVMAYDRYLAIAKPLHYVTMMRKEVWVALVVASWVSGGLHSIIQVILMLPFPFCGPNTLDAFYCYVLQVVKLACTDTFALELFMISNNGLVTLLWFLLLLGSYT-VILVMLRSHSGEGRNKALSTCTSHMLVVTLHFVPCVYIYCRPFM--TLPM--DTTISINNTVITPMLNPIIYS------------------LRNQEMK-----------SAMQRLQR--------RLGPSESRKWG-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGL7-1", "uniprot_id": "OR4P4_HUMAN", "id": "Q8NGL7-1", "name": "Olfactory receptor 4P4", "aln": "----------------------------------------------------MEKSNN---STLFILLGFSQNKN-IEVLCFVLFLFCYIAIWMGNLLIMISITCTQL-IHQPMYFFLNYLSLSDLCYTSTVTPKLMVDLLAERKTISYNNCMIQLFTTHFFGGIEIFILTGMAYDRYVAICKPLHYTIIMSRQKCNTIIIVCCTGGFIHSASQFLLTIFVPFCGPNEIDHYFCDVYPLLKLACSNIHMIGLLVIANSGLIALVTFVVLLLSYV-FILYTIRAYSAERRSKALATCSSHVIVVVLFFAPALFIYIRPVT--TFSE--DKVFALFYTIIAPMFNPLIYT------------------LRNTEMK-----------NAMRKVWC--------CQILLKRNQLF-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGB4-1", "uniprot_id": "OR4S1_HUMAN", "id": "Q8NGB4-1", "name": "Olfactory receptor 4S1", "aln": "----------------------------------------------------MGAKNN---VTEFVLFGLFESRE-MQHTCFVVFFLFHVLTVLGNLLVIITINARKT-LKSPMYFFLSQLSFADICYPSTTIPKMIADTFVEHKIISFNGCMTQLFSAHFFGGTEIFLLTAMAYDRYVAICRPLHYTAIMDCRKCGLLAGASWLAGFLHSILQTLLTVQLPFCGPNEIDNFFCDVHPLLKLACADTYMVGLIVVANSGMISLASFFILIISYV-IILLNLRSQSSEDRRKAVSTCGSHVITVLLVLMPPMFMYIRPST--TLAA--DKLIILFNIVMPPLLNPLIYT------------------LRNNDVK-----------NAMRKLFR--------VKRSLGEK----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGM1-1", "uniprot_id": "OR4CF_HUMAN", "id": "Q8NGM1-1", "name": "Olfactory receptor 4C15", "aln": "----------------------------------------------------MQNQSF---VTEFVLLGLSQNPN-VQEIVFVVFLFVYIATVGGNMLIVVTILSSPALLVSPMYFFLGFLSFLDACFSSVITPKMIVDSLYVTKTISFEGCMMQLFAEHFFAGVEVIVLTAMAYDRYVAICKPLHYSSIMNRRLCGILMGVAWTGGLLHSMIQILFTFQLPFCGPNVINHFMCDLYPLLELACTDTHIFGLMVVINSGFICIINFSLLLVSYA-VILLSLRTHSSEGRWKALSTCGSHIAVVILFFVPCIFVYTRPPS--AFSL--DKMAAIFYIILNPLLNPLIYT------------------FRNKEVK-----------QAMRRIWN--------RLMVVSDEKENIKL----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH37-1", "uniprot_id": "OR4C3_HUMAN", "id": "Q8NH37-1", "name": "Olfactory receptor 4C3", "aln": "----------------------------------------------------MDIPQN---ITEFFMLGLSQNSE-VQRVLFVVFLLIYVVTVCGNMLIVVTITSSPT-LASPVYFFLANLSFIDTFYSSSMAPKLIADSLYEGRTISYECCMAQLFGAHFLGGVEIILLTVMAYDRYVAICKPLHNTTIMTRHLCAMLVGVAWLGGFLHSLVQLLLVLWLPFCGPNVINHFACDLYPLLEVACTNTYVIGLLVVANSGLICLLNFLMLAASYI-VILYSLRSHSADGRCKALSTCGAHFIVVALFFVPCIFTYVHPFS--TLPI--DKNMALFYGILTPMLNPLIYT------------------LRNEEVK-----------NAMRKLFT--------W-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH83-1", "uniprot_id": "OR4A5_HUMAN", "id": "Q8NH83-1", "name": "Olfactory receptor 4A5", "aln": "----------------------------------------------------MRQNNN---ITEFVLLGFSQDPG-VQKALFVMFLLTYLVTVVGNLLIVVDIIASPS-LGSPMYFFLACLSFIDAAYSTTISPKLIVGLFCDKKTISFQGCMGQLFIDHFFGGAEVFLLVVMACDRYVAICKPLHYLTIMNRQVCFLLLVVAMIGGFVHSAFQIV-VYSLPFCGPNVIVHFSCDMHPLLELACTDTYFIGLTVVVNSGAICMVIFNLLLISYG-VILSSLKTYSQEKRGKALSTCSSGSTVVVLFFVPCIFIYVRPVS--NFPT--DKFMTVFYTIITHMLSPLIYT------------------LRNSEMR-----------NAIEKLLG--------KKLTIF---IIGGVSVLM------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH70-1", "uniprot_id": "O4A16_HUMAN", "id": "Q8NH70-1", "name": "Olfactory receptor 4A16", "aln": "----------------------------------------------------MRPSSN---VTEFVLLGLTQDPD-VKKTLFVMFLLIYIVTMVGNLLIWVTTIGSPS-LGSLMYFFLAYLSLMDAIYSTAMSPKLMIDLLCDKIAISLSACMGQLFIEHLLGGAEVFLLVVMAYDRYVAISKPLHYLNIMNRLVCILLLVVAMIGGFVHSVVQIVFLYSLPICGPNVIDHSVCDMYPLLELLCLDTYFIGLTVVANGGIICMVIFTFLLISCG-VILNFLKTYSQEERHKALPTCISHIIVVALVFVPCIFMYVRPVS--NFPF--DKLMTVFYSIITLMLNPLIYS------------------LRQSEMK-----------NAMKNLWC--------EKLSIVRKRVSPTLNIFIPSSKATNRR---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IF82-1", "uniprot_id": "O4A47_HUMAN", "id": "Q6IF82-1", "name": "Olfactory receptor 4A47", "aln": "----------------------------------------------------MEPRKN---VTDFVLLGFTQNPK-EQKVLFVMFLLFYILTMVGNLLIVVTVTVSET-LGSPMYFFLAGLSFIDIIYSSSISPRLISGLFFGNNSISFQSCMAQLFIEHIFGGSEVFLLLVMAYDCYVAICKPLHYLVIMRQWVCVVLLVVSWVGGFLHSVFQLSIIYGLPFCGPNVIDHFFCDMYPLLKLVCTDTHAIGLLVVANGGLACTIVFLLLLISYG-VILHSLKNLSQKGRQKALSTCSSHMTVVVFFFVPCIFMYARPAR--TFPI--DKSVSVFYTVITPMLNPLIYT------------------LRNSEMT-----------SAMKKLWR--------RDLISSST----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGN8-1", "uniprot_id": "OR4A4_HUMAN", "id": "Q8NGN8-1", "name": "Putative olfactory receptor 4A4", "aln": "----------------------------------------------------MEPRKN---VTDFVLLGFTQNPK-EQKVLFVMFLLFYILTMVGNLLIVVTVTVSET-LGSPMSFFLAGLTFIDIIYSSSISPRLISDLFFGNNSISFQSFMAQLFIEHLFGGSEVFLLLVMAYDRYVAICKPLHYLVIMRQWVCVLLLVVSWVGGFLQSVFQLSIIYGLPFCGPNVIDHFFCDMYPLLKLACTDTHVIGLLVVANGGLSCTIAFLLLLISYG-VILHSLKKLSQKGRQKAHSTCSSHITVVVFFFVPCIFMCARPAR--TFSI--DKSVSVFYTVITPMLNPLIYT------------------LRNSEMT-----------SAMKKL----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGL6-1", "uniprot_id": "O4A15_HUMAN", "id": "Q8NGL6-1", "name": "Olfactory receptor 4A15", "aln": "----------------------MELLTNNLKFITDPFVCRLRHLSPTPSEEHMKNKNN---VTEFILLGLTQNPE-GQKVLFVTFLLIYMVTIMGNLLIIVTIMASQS-LGSPMYFFLASLSFIDTVYSTAFAPKMIVDLLSEKKTISFQGCMAQLFMDHLFAGAEVILLVVMAYDRYMAICKPLHELITMNRRVCVLMLLAAWIGGFLHSLVQFLFIYQLPFCGPNVIDNFLCDLYPLLKLACTNTYVTGLSMIANGGAICAVTFFTILLSYG-VILHSLKTQSLEGKRKAFYTCASHVTVVILFFVPCIFLYARPNS--TFPI--DKSMTVVLTFITPMLNPLIYT------------------LKNAEMK-----------SAMRKLWS--------KKVSLAGKWLYHS-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NHA9-1", "uniprot_id": "O4C46_HUMAN", "id": "A6NHA9-1", "name": "Olfactory receptor 4C46", "aln": "----------------------------------------------------MENRNN---MTEFVLLGLTENPK-MQKIIFVVFFVIYIITVVGYVLIVVTITASPS-LGSPMYLSLAYLSFIDACYSSVNTPNLITHSLYGKKAILFNGCMTQVFGEHFFGGAEGILLTVMAYDHYVAICKPLHYMTIMNQCVCALLMGVVWMGGFLHATIQILFIFQLPFCGPNVIDHFMCDLNPLLNLACTDTHMLELFIAANSGFICLLNFALLLVSYV-VILCSLRTHSLEARHKALSTCVSHITVVILFFVPCIFVYMRPAA--TLPI--DKAVAIFYTMITPMLNPLIYT------------------LKNAQMK-----------NAIRKLCS--------RKDISGDK----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGP0-1", "uniprot_id": "OR4CD_HUMAN", "id": "Q8NGP0-1", "name": "Olfactory receptor 4C13", "aln": "----------------------------------------------------MANRNN---VTEFILLGLTENPK-MQKIIFVVFSVIYINAMIGNVLIVVTITASPS-LRSPMYFFLAYLSFIDACYSSVNTPKLITDSLYENKTILFNGCMTQVFGEHFFRGVEVILLTVMAYDHYVAICKPLHYTTVMKQHVCSLLVGVSWVGGFLHATIQILFICQLPFCGPNVIDHFMCDLYTLINLACTNTHTLGLFIAANSGFICLLNCLLLLVSCV-VILYSLKTHSLEARHEALSTCVSHITVVILSFIPCIFVYMRPPA--TLPI--DKAVAVFYTMITSMLNPLIYT------------------LRNAQMK-----------NAIRKLCS--------RKAISSVK----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96R67-1", "uniprot_id": "OR4CC_HUMAN", "id": "Q96R67-1", "name": "Olfactory receptor 4C12", "aln": "----------------------------------------------------MEKKKN---VTEFILIGLTQNPI-MEKVTFVVFLVLYMITLSGNLLIVVTITTSQA-LSSPMYFFLTHLSLIDTVYSSSSAPKLIVDSFQEKKIISFNGCMAQAYAEHIFGATEIILLTVMACDCYVAICKPLNYTTIMSHSLCILLVAVAWVGGFLHATIQILFTVWLPFCGPNVIGHFMCDLYPLLKLVCIDTHTLGLFVAVNSGFICLLNFLILVVSYV-IILRSLKNNSLEGRCKALSTCISHIIVVVLFFVPCIFVYLRSVT--TLPI--DKAVAVFYTMVVPMLNPVVYT------------------LRNAEVK-----------SAIRKLWR--------KKVTSDND----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH72-1", "uniprot_id": "OR4C6_HUMAN", "id": "Q8NH72-1", "name": "Olfactory receptor 4C6", "aln": "----------------------------------------------------MENQNN---VTEFILLGLTENLE-LWKIFSAVFLVMYVATVLENLLIVVTIITSQS-LRSPMYFFLTFLSLLDVMFSSVVAPKVIVDTLSKSTTISLKGCLTQLFVEHFFGGVGIILLTVMAYDRYVAICKPLHYTIIMSPRVCCLMVGGAWVGGFMHAMIQLLFMYQIPFCGPNIIDHFICDLFQLLTLACTDTHILGLLVTLNSGMMCVAIFLILIASYT-VILCSLKSYSSKGRHKALSTCSSHLTVVVLFFVPCIFLYMRPVV--THPI--DKAMAVSDSIITPMLNPLIYT------------------LRNAEVK-----------SAMKKLW----------MKWEALAGK--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGB2-1", "uniprot_id": "OR4C5_HUMAN", "id": "Q8NGB2-1", "name": "Olfactory receptor 4C5", "aln": "-----------------------------MYVSNCNPCAIHRKINYPNTKLDFEQVNN---ITEFILLGLTQNAE-AQKLLFAVFTLIYFLTMVDNLIIVVTITTSPA-LDSPVYFFLSFFSFIDGCSSSTMAPKMIFDLLTEKKTISFSGCMTQLFVEHFFGGVEIILLVVMAYDCYVAICKPLYYLITMNRQVCGLLVAMAWVGGFLHALIQMLLIVWLPFCGPNVIDHFICDLFPLLKLSCTDTHVFGLFVAANSGLMCMLIFSILITSYV-LILCSQR--------KALSTCAFHITVVVLFFVPCILVYLRPMI--TFPI--DKAVSVFYTVVTPMLNPLIYT------------------LRNTEVK-----------NAMKQLWS--------QIIWGNNLCD--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IEV9-1", "uniprot_id": "OR4CB_HUMAN", "id": "Q6IEV9-1", "name": "Olfactory receptor 4C11", "aln": "----------------------------------------------------MQQNNS---VPEFILLGLTQDPL-RQKIVFVIFLIFYMGTVVGNMLIIVTIKSSRT-LGSPMYFFLFYLSFADSCFSTSTAPRLIVDALSEKKIITYNECMTQVFALHLFGCMEIFVLILMAVDRYVAICKPLRYPTIMSQQVCIILIVLAWIGSLIHSTAQIILALRLPFCGPYLIDHYCCDLQPLLKLACMDTYMINLLLVSNSGAICSSSFMILIISYI-VILHSLRNHSAKGKKKALSACTSHIIVVILFFGPCIFIYTRPPT--TFPM--DKMVAVFYTIGTPFLNPLIYT------------------LRNAEVK-----------NAMRKLWH--------GKIISENKG---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGF9-1", "uniprot_id": "OR4X2_HUMAN", "id": "Q8NGF9-1", "name": "Olfactory receptor 4X2", "aln": "-------------------------------------------------------------MTEFIFLVLSPNQE-VQRVCFVIFLFLYTAIVLGNFLIVLTVMTSRS-LGSPMYFFLSYLSFMEICYSSATAPKLISDLLAERKVISWWGCMAQLFFLHFFGGTEIFLLTVMAYDHYVAICKPLSYTTIMNWQVCTVLVGIAWVGGFMHSFAQILLIFHLLFCGPNVINHYFCDLVPLLKLACSDTFLIGLLIVANGGTLSVISFGVLLASYM-VILLHLRTWSSEGWCKALSTCGSHFAVVILFFGPCVFNSLRPST--TLPI--DKMVAVFYTVITAILNPVIYS------------------LRNAEMR-----------KAMKRLWI--------RTLRLNEK----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH49-1", "uniprot_id": "OR4X1_HUMAN", "id": "Q8NH49-1", "name": "Olfactory receptor 4X1", "aln": "----------------------------------------------------MVATNN---VTEIIFVGFSQNWS-EQRVISVMFLLMYTAVVLGNGLIVVTILASKV-LTSPMYFFLSYLSFVEICYCSVMAPKLIFDSFIKRKVISLKGCLTQMFSLHFFGGTEAFLLMVMAYDRYVAICKPLHYMAIMNQRMCGLLVRIAWGGGLLHSVGQTFLIFQLPFCGPNIMDHYFCDVHPVLELACADTFFISLLIITNGGSISVVSFFVLMASYL-IILHFLRSHNLEGQHKALSTCASHVTVVDLFFIPCSLVYIRPCV--TLPA--DKIVAVFYTVVTPLLNPVIYS------------------FRNAEVK-----------NAMRRFIG--------GKVI--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8YED5-1", "uniprot_id": "O5BS1_HUMAN", "id": "A0A2R8YED5-1", "name": "Olfactory receptor 5BS1", "aln": "--------------------------------------------------MEVSNMTT---VTVFILLGLSNNPQ-VQALLFVLFLVIYLLTLLGNLLMVLVISTDSH-LCTPMYFFLRQLSFLDAFYSSIIVPKLLENLLSKGETISFLECFTQISLVIFSGATEACLLSVMAYDRFQAMCHPLLYVVIINRRVCAGLVGASWAIGMGTGLINTLLLAQQHFCGPNVIHSFACELPPVLLLTCSDPCASIVSILTTMSVLGLGTLVLLLGSYSCIIMTALRINSATGRSKIFSTCSSHFLVVTIFYTSGVLRYMIPAS--GSAL--EQVLSVQYSVITPLLNPLIYS------------------LKSQEVK-----------VALRRMLAR------KSR----------------LPL---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH09-1", "uniprot_id": "OR8S1_HUMAN", "id": "Q8NH09-1", "name": "Olfactory receptor 8S1", "aln": "--------------------------------------------------MALGNHST---ITEFLLLGLSADPN-IRALLFVLFLGIYLLTIMENLMLLLMIRADSC-LHKPMYFFLSHLSFVDLCFSSVIVPKMLENLLSQRKTISVEGCLAQVFFVFVTAGTEACLLSGMAYDRHAAICRPLLYGQIMGKQLYMHLVWGSWGLGFLDALINVLLAVNMVFCEAKIIHHYSYEMPSLLPLSCSDISRSLIALLCSTLLHGLGNFLLVFLSYTRIISTILSISSTSGRSKAFSTCSAHLTAVTLYYGSGLLRHLMPNS--GSPI--ELIFSVQYTVVTPMLNSLIYS------------------LKNKEVKGERSLRDSSHLPQLHKGQAR------WKRPAFTEGRREPGHPELSIPVTPQPQGACACSALRAAPTALP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGX8-1", "uniprot_id": "OR6Y1_HUMAN", "id": "Q8NGX8-1", "name": "Olfactory receptor 6Y1", "aln": "---------------------------------------------MTTIILEVDNHTV---TTRFILLGFPTRPA-FQLLFFSIFLATYLLTLLENLLIILAIHSDGQ-LHKPMYFFLSHLSFLEMWYVTVISPKMLVDFLSHDKSISFNGCMTQLYFFVTFVCTEYILLAIMAFDRYVAICNPLRYPVIMTNQLCGTLAGGCWFCGLMTAMIKMVFIAQLHYCGMPQINHYFCDISPLLNVSCEDASQAEMVDFFLALMVIAIPLCVVVASYAAILATILRIPSAQGRQKAFSTCASHLTVVILFYSMTLFTYARPKL--MYAYNSNKVVSVLYTVIVPLLNPIIYC------------------LRNHEVK-----------AALRKTIHCR------GSGPQGNGAFSS------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3V8B7-1", "uniprot_id": "G3V8B7_RAT", "id": "G3V8B7-1", "name": "Olfactory receptor", "aln": "-------------------------------------------------MENIACNGSGDSQTSFYLIGIPSLQKSLFLPVFFIFLLLYLLILMGNTLILVAVVAEPS-LHKPMYFFLINLSALDILFTTTTVPKMLSLLLLGDRLLSFPACFLQMYLFHSFSCSEAFILVVMAYDRYVAICRPLHYPVHMTPQTNTALAASAWITALLLPIPAVVQTSHMAFDNIAYIYHCFCDHLAVVQASCSDTSPQTLMGFCIAMVVSFLPLLLVLLSYVRILISVLRINSKEGRSKAFSTCSSHLLVVGTYYSSIAISYVAYRA--DLPVDFHIMGNVVYAILTPVLNPIIYT------------------LRNKDVK-----------AAITKIVC--------HQDPKSIGKP--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q519-1", "uniprot_id": "E9Q519_MOUSE", "id": "E9Q519-1", "name": "Olfactory receptor", "aln": "-------------------------------------------------MENIACNGSGNSQTSFYLTGIPSLQKSLFLPVFLIFLLLYLLILVGNALILVAVVTERS-LHKPMYFFLINLSALDILFTTTTVPKMLSLLLLGDRFLSFPACFLQMYLFHSFSCSEAFILVVMAYDRYVAICRPLHYPVHMTPQTNTALAASAWITALLLPIPAVIQTSQMAFDNIAYIYHCFCDHLAVVQASCSDTTPQTLMGFCIAMVVSFLPLLLVLLSYARILSSVLRINSKEGRSKAFSTCSSHLLVVGTYYSSIAIAYVAYRA--DLPLDFHIMGNVVYAILTPVLNPLIYT------------------LRNKDVK-----------SAITKMMC--------HQDPKSIGKP--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RC72-1", "uniprot_id": "M0RC72_RAT", "id": "M0RC72-1", "name": "Olfactory receptor", "aln": "-------------MCELQYAIENLVPAKPCAGTLDVPATHDPDLRFCSTMETTTCNGSVDGSTVFYLVGIPSLPEPFYLPVFFLFLLFYLLILMGNTLILVAVVAEPS-LHKPMYFFLINLSALDILFTTTTVPKMLSLLLLGDRFLSFPSCLLQMYLFQSFTCSEAFILVVMAYDRYVAICRPLHYPVHMTPQTNTALAASAWITALLLPVPAVVKTSQMVYNDVAYIYHCFCDHLALVQSSCSDTTPQTLMGFCIAMVVSFLPLLLVLLSYVRILISVLRINSKEGRSKAFSTCSSHLLVVGTYYSSIAIAYVAYRA--DLPLDFHIMGNVVYSILTPILNPLIYT------------------LRNKDVK-----------AAITKIVY--------LKSVM-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q518-1", "uniprot_id": "E9Q518_MOUSE", "id": "E9Q518-1", "name": "Olfactory receptor", "aln": "-------------------------------------------------MEATTCNGSVDGSTVFYLVGIPSLPEPFYLPVFFLFLLFYLLILVGNALILVAVVAERS-LHKPMYFFLINLSALDILFTTTTVPKMLSLLLLGDRFLSFPACLLQMYLFQSFTCSEAFILVVMAYDRYVAICRPLHYPVHMTPQTNTALAASAWITALLLPVPAVVKTSQMVYNDIAYIYHCFCDHLALVQSSCSDTTPQTLMGFCIAMVVSFLPLLLVLLSYVRILTSVLRINSKEGRSKAFSTCSSHLLVVGTYYSSIAIAYVAYRA--NLPLDFHIMGNVVYSILTPILNPLIYT------------------LRNKDVK-----------VAITKIVY--------LKGMM-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NND4-1", "uniprot_id": "O2AT4_HUMAN", "id": "A6NND4-1", "name": "Olfactory receptor 2AT4", "aln": "-------------------------------------------------MDATACNESVDGSPVFYLLGIPSLPETFFLPVFFIFLLFYLLILMGNALILVAVVAEPS-LHKPMYFFLINLSTLDILFTTTTVPKMLSLFLLGDRFLSFSSCLLQMYLFQSFTCSEAFILVVMAYDRYVAICHPLHYPVLMNPQTNATLAASAWLTALLLPIPAVVRTSQMAYNSIAYIYHCFCDHLAVVQASCSDTTPQTLMGFCIAMVVSFLPLLLVLLSYVHILASVLRISSLEGRAKAFSTCSSHLLVVGTYYSSIAIAYVAYRA--DLPLDFHIMGNVVYAILTPILNPLIYT------------------LRNRDVK-----------AAITKIMS--------QDPGCDRSI---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PRJ2-1", "uniprot_id": "Q9PRJ2_DANRE", "id": "Q9PRJ2-1", "name": "Olfactory receptor", "aln": "-----------------------------------------------------MSAGNISFVKEFFIVGFPGLQKGYFDSVAALMLFVFVCILAGNGTFLILFSLEKS-LHKPMYYVILNLVASDILFSTTTLPKIIARYLFQDGGISFMGCFIQMYFVHYFGTVNAFILAIMAFDRYVAICNPLRYPNIVTKWNIFYLCLISWVIANVTPLMMVIRAYPLPYCAENTIIQCYCDHISITSLACTNRAPYSIPAFVLAMVALLTPLAFIVFSYCAIILAVLRISSTQARLKTFSTCSPQLIIIALYFLPRCFIYLSSNIGIYFSTDLRLAIIMMYSLFPPMFNPLIYC------------------LRTKDVK-----------ECLVKRLK--------ISTNVKFNLTKVDISSVSS-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . . : : : . * .: : : * *. : . .: : . * . : : . : : : ", "identical_positions": 4, "similar_positions": 27, "identity": "0.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000329-17", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACL4-1", "uniprot_id": "D4ACL4_RAT", "id": "D4ACL4-1", "name": "", "aln": "MGEHNLLNPGFVG-------------PLVNIHTGDTFYFPN-FRASGAQLPGLPSLSYPRRDN----VCSLP--------------------------WPSAEPCNGYPQPYLGSPVSLN--------------------------PPFGRTCELARVEDSKGYYREP-------CAEGGGGGLKREERGREPGAGPGAALLQLEPSGPPALG-------------------------------------------------FKYDYPAGGGGGDGN--TGPPHDPPS------------CQSLESDSSSSLLNEGNKGASAGDPGSLVSP----LNPGGGLSASGAPWYPIHSRS-------------------------------RKKRKPYSKLQLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKRLLLREQALSFF--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K5B8-1", "uniprot_id": "HXC12_MOUSE", "id": "Q8K5B8-1", "name": "Homeobox protein Hox-C12", "aln": "MGEHNLLNPGFVG-------------PLVNIHTGDTFYFPN-FRASGAQLPGLPSLSYPRRDN----VCSLP--------------------------WPSAEPCNGYPQPYLGSPVSLN--------------------------PPFGRTCELARVEDSKGYYREP-------CAEGGGGGLKREERGREPGAGPGAALLQLEPSGPPALG-------------------------------------------------FKYDYTASGGGGDGS--TGPPHDPPS------------CQSLESDSSSSLLNEGNKSASAGDPGSLVSP----LNPGGGLSASGAPWYPIHSRS-------------------------------RKKRKPYSKLQLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKRLLLREQALSFF--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31275-1", "uniprot_id": "HXC12_HUMAN", "id": "P31275-1", "name": "Homeobox protein Hox-C12", "aln": "MGEHNLLNPGFVG-------------PLVNIHTGDTFYFPN-FRASGAQLPGLPSLSYPRRDN----VCSLS--------------------------WPSAEPCNGYPQPYLGSPVSLN--------------------------PPFGRTCELARVEDGKGYYREP-------CAEGGGGGLKREERGRDPGAGPGAALLPLEPSGPPALG-------------------------------------------------FKYDYAAGGGGGDGGGGAGPPHDPPS------------CQSLESDSSSSLLNEGNKGAGAGDPGSLVSP----LNPGGGLSASGAPWYPINSRS-------------------------------RKKRKPYSKLQLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKRLLLREQALSFF--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9YGT0-1", "uniprot_id": "HXCCB_DANRE", "id": "Q9YGT0-1", "name": "Homeobox protein Hox-C12b", "aln": "MGEHNLFNPGFVG-------------QLVNINARDAFYLSN-FRASGGQLAGLQTLRLSRRDN----VCSLP--------------------------WNPSEACSGYPQSHISGPVTLN--------------------------HTYNQSCDITRQEDNKCFYSDSA------CATSGGGDNNSTNLISKEGALDNSSVSITAENGQNNLN-------------------------------------------------GMDNGGSYSKYDCLTPAEQPIPNPRL------------CRSLESVSGCSFINEGAK-TSSGITHSLTSPD---IQTSVAALNGGALWYPMHRQT-------------------------------RKKRKPYSKLQLNELEGEFILNEFITRQRRRELSDRLNLTDQQVKIWFQNRRMKKKRLLMREQALSYF--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09087-1", "uniprot_id": "ABDB_DROME", "id": "P09087-1", "name": "Homeobox protein abdominal-B", "aln": "MQQHHLQQQQQQQQQQEQQHLQEQQQHLQQLHHHAHHHLPQPLHTTSHHHSAHPHLQQQQQQQQHAVVASSPSSVLQQQQQQSTPTTHSTPTHAVMYEDPPPVPLVAVQQQHLPAPQQQQQLQQQQQQQQQQLATTPVAGALSPAQTPTGPSAQQQQHLTSPHHQQLPQQQTPNSVASGASSNLQQQQQQQNAAVAPGQTQIVAPTTASVSPSSVSSQKEDINMSIQLAPLHIPAIRAGPGFETDTSAAVKRHTAHWAYNDEGFNQHYGSGYYDRKHMFAYPYPETQFPVGQYWGPNYRPDQTTSAAAAAAYMNEAERHVSAAARQSVEGTSTSSYEPPTYSSPGGLRGYPSENYSSSGASGGLSVGAVGPCTPNPGLHEWTGQVSVRKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRMKNKKNSQRQANQQNNNNNSSSNHNHAQATQQHHSGHHLNLSLNMGHHAAKMHQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :*:* : * ::: .::.: ::::. : .. * :::: *.* . .. . . * :: .* : . . :.: : . . . * ..... : : . .. . : .. . : . . . * :. :: .: :..: :**. : ..:. *: .. :. .* ** . : *********:* *** **:.* ::::*:* **: .*:*:::************:*: *: . ", "identical_positions": 53, "similar_positions": 104, "identity": "10.75%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000329-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18864-1", "uniprot_id": "HXB7_RAT", "id": "P18864-1", "name": "Homeobox protein Hox-B7", "aln": "--MSS-------LYYAN---------------------------------------------------------------ALFSKYPAASSVFAPGAFPEQTS----------------------------------------CAFASNPQRP-GYG-AGPGAPFSAS----VQGLYSGGG------GMAGQSAAGVYEAGYGLEP-----------------SSFNMHCAPFEQ-NLSGVCPGDP--------------AKA--AGAKEQRDSDLAAESN---FRIYPWMRSSG---TERKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTSGPGTTGQDKAEADEEEEEEE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09024-1", "uniprot_id": "HXB7_MOUSE", "id": "P09024-1", "name": "Homeobox protein Hox-B7", "aln": "--MSS-------LYYAN---------------------------------------------------------------ALFSKYPAASSVFAPGAFPEQTS----------------------------------------CAFASNPQRP-GYG-AGPGAPFSAS----VQGLYSGGG------AMAGQSAAGVYAAGYGLEP-----------------SSFNMHCAPFEQ-NLSGVCPGDP--------------AKA--AGAKEQRDSDLAAESN---FRIYPWMRSSG---PDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWKKENKTSGPGTTGQDKAEAEEEEEE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09629-1", "uniprot_id": "HXB7_HUMAN", "id": "P09629-1", "name": "Homeobox protein Hox-B7", "aln": "--MSS-------LYYAN---------------------------------------------------------------TLFSKYPASSSVFATGAFPEQTS----------------------------------------CAFASNPQRP-GYG-AGSGASFAAS----MQGLYPGGG------GMAGQSAAGVYAAGYGLEP-----------------SSFNMHCAPFEQ-NLSGVCPGDS--------------AKA--AGAKEQRDSDLAAESN---FRIYPWMRSSG---TDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWKKENKTAGPGTTGQDRAEAEEEEEE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AWY9-1", "uniprot_id": "HXB7A_DANRE", "id": "Q8AWY9-1", "name": "Homeobox protein Hox-B7a", "aln": "--MSS-------LYYAN---------------------------------------------------------------ALFSKYQVASSAFSTGVFPEQTS----------------------------------------CAFSCSSQRASGYGSASTGAPVSSSSSVSLPSMYTNGT------SLS-SHTQGMYPTAYELGA-----------------VSLNMHSSLFDHPNLPMVSAGDL--------------CKAQSSGKEEQRGYHQNNENN---LRIYPWMRSTG---ADRKRGRQTYSRYQTLELEKEFHFNRYLSRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKSTDRCSPAADQIGGDEEEEDDE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P02833-1", "uniprot_id": "ANTP_DROME", "id": "P02833-1", "name": "Homeotic protein antennapedia", "aln": "MTMSTNNCESMTSYFTNSYMGADMHHGHYPGNGVTDLDAQQMHHYSQNANHQGNMPYPRFPPYDRMPYYNGQGMDQQQQHQVYSRPDSPSSQVG-GVMPQAQTNGQLGVPQQQQQQQQQPSQNQQQQQAQQAPQQLQQQLPQVTQQVTHPQQQQQQPVVYASCKLQAAVG--GLGMVPEGGSPPLVDQMSGHHMNAQMTLPHHMGHPQAQLGYTDVGVPDVTEVHQNHHNMGMYQ-QQSGVPPVGAPPQGMMHQGQGPPQMHQGHPGQHTPPSQNPNSQSSGMPSPLYPWMRSQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTKGEPGSGGEGDEITPPNSPQ-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CY11-1", "uniprot_id": "HMRA1_YEAST", "id": "P0CY11-1", "name": "Silenced mating-type protein A1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDDICSMAENINR-----------------TLFNILGTEIDEINLNTNNLYNF--------------IMESNLTKVEQHTLHKNISNNR--LEIYHHIKKEK-----SPKGKSSISPQARAFLEQVFRRKQSLNSKEKEEVAKKCGITPLQVRVWFINKRMRSK--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : . : . . ... :* ::. :*:.: : **: *: :: *. :.: *:*: :* *:::** *:**: * ", "identical_positions": 17, "similar_positions": 34, "identity": "4.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000329-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60709-1", "uniprot_id": "ACTB_HUMAN", "id": "P60709-1", "name": "Actin, cytoplasmic 1", "aln": "-MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60711-1", "uniprot_id": "ACTB_RAT", "id": "P60711-1", "name": "Actin, cytoplasmic 1", "aln": "-MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60710-1", "uniprot_id": "ACTB_MOUSE", "id": "P60710-1", "name": "Actin, cytoplasmic 1", "aln": "-MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7ZVF9-1", "uniprot_id": "ACTB2_DANRE", "id": "Q7ZVF9-1", "name": "Actin, cytoplasmic 2", "aln": "-MDDEIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMGTAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITSLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P63260-1", "uniprot_id": "ACTG_MOUSE", "id": "P63260-1", "name": "Actin, cytoplasmic 2", "aln": "-MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63261-1", "uniprot_id": "ACTG_HUMAN", "id": "P63261-1", "name": "Actin, cytoplasmic 2", "aln": "-MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10987-1", "uniprot_id": "ACT1_DROME", "id": "P10987-1", "name": "Actin-5C", "aln": "MCDEEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P02572-1", "uniprot_id": "ACT2_DROME", "id": "P02572-1", "name": "Actin-42A", "aln": "MCDEEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIVAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P60010-1", "uniprot_id": "ACT_YEAST", "id": "P60010-1", "name": "Actin", "aln": "-MDSEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGIMVGMGQKDSYVGDEAQSKRGILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKSNREKMTQIMFETFNVPAFYVSIQAVLSLYSSGRTTGIVLDSGDGVTHVVPIYAGFSLPHAILRIDLAGRDLTDYLMKILSERGYSFSTTAEREIVRDIKEKLCYVALDFEQEMQTAAQSSSIEKSYELPDGQVITIGNERFRAPEALFHPSVLGLESAGIDQTTYNSIMKCDVDVRKELYGNIVMSGGTTMFPGIAERMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLTTFQQMWISKQEYDESGPSIVHHKCF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.::****:********************************:************************:*****************************************:***:**************.**:**:********:********:******:*.**** *::*******:***************:******:************************** ***.***:********************.**:**:**.**:*:.**.:**:*********:**:**.* *:******:****:*******:****:**:**:*******************:*********************:***", "identical_positions": 326, "similar_positions": 45, "identity": "86.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000329-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q04721-1", "uniprot_id": "NOTC2_HUMAN", "id": "Q04721-1", "name": "Neurogenic locus notch homolog protein 2", "aln": "MPALRPALLWALLALWLCCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVA--QAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVAN-QFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCAR--GPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQS----SCGQVKCRKGEQCVHTASGPRCFCPS---PRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINN-QCDELCNTVECLFDNFECQGNSKT--CKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADQPENLAEGTLVIVVLMPPEQLLQDARSFLRALGTLLHTNLRIKRDSQGELMVYPYYGEKSAAMKKQRMTRRSLP--GEQEQEVAGSKVFLEIDNRQCVQDSDHCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPERTQLLYLLAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRDASNHKRREPVGQDAVGLKNLSVQVSEANLIGTGTSEHWVDDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHLEAADIRRTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSD-----LSDEDED--AEDSSANIITDLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITDHMDRLPRDVARDRMHHDIVRLLDEYNVTPSP---PGTVLTS-ALSPVICGPNRS--FLSLKHTPMGKKSRRPSAKSTMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSESSVTLSPVDSLESPHTYVSDTTSSPMITSPGILQASPNPMLATAAPPAPVHAQHALSFSNLHEMQPLAHGASTVLPSVSQLLSHHHIVSPGSGSAGSLSRLHPVPVPADWMNRMEVNETQYNEMFGMVLAPAEGTHPGIAP-QSRPPEGKHITTPREPLPPIVTFQLIPKGS-----------IAQPAGAPQPQSTCPPAVAGPLPTMYQIPEMARLPSVAFPTAMMPQQDGQVAQTILP--------AYHPFPASVGKYPTPPSQHSYASSNAAERTPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGG-------------AGGGQRGPGTHMSEPPHNN----MQVYA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35516-1", "uniprot_id": "NOTC2_MOUSE", "id": "O35516-1", "name": "Neurogenic locus notch homolog protein 2", "aln": "MPALRPAALRALLWLWLCGAGPAHALQCRGGQEPCVNEGTCVTYHNGTGFCRCPEGFLGEYCQHRDPCEKNRCQNGGTCVP--QGMLGKATCRCAPGFTGEDCQYSTSHPCFVSRPCQNGGTCHMLSRDTYECTCQVGFTGKQCQWTDACLSHPCENGSTCTSVAS-QFSCKCPAGLTGQKCEADINECDIPGRCQHGGTCLNLPGSYRCQCPQGFTGQHCDSPYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHKCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCTNRNGGYGCVCVNGWSGDDCSENIDDCAYASCTPGSTCIDRVASFSCLCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEVNECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGILCDENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGLNCEINFDDCASNPCMHGVCVDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINDVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGVNCEVDKNECLSNPCQNGGTCNNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDVSGYTCHCMLPYTGKNCQTVLAPCSPNPCENAAVCKEAPNFESFSCLCAPGWQGKRCTVDVDECISKPCMNNGVCHNTQGSYVCECPPGFSGMDCEEDINDCLANPCQNGGSCVDHVNTFSCQCHPGFIGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCTCPAGFHGVHCENNIDECTESSCFNGGTCVDGINSFSCLCPVGFTGPFCLHDINECSSNPCLNAGTCVDGLGTYRCICPLGYTGKNCQTLVNLCSRSPCKNKGTCVQEKARPHCLCPPGWDGAYCDVLNVSCKAAALQKGVPVEHLCQHSGICINAGNTHHCQCPLGYTGSYCEEQLDECASNPCQHGATCNDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDECAG--GPHCLNGGQCVDRIGGYTCRCLPGFAGERCEGDINECLSNPCSSEGSLDCVQLKNNYNCICRSAFTGRHCETFLDVCPQKPCLNGGTCAVASNMPDGFICRCPPGFSGARCQS----SCGQVKCRRGEQCIHTDSGPRCFCLN---PKDCESGCASNPCQHGGTCYPQRQPPHYSCRCPPSFGGSHCELYTAPTSTPPATCQSQYCADKARDGICDEACNSHACQWDGGDCSLTMEDPWANCTSTLRCWEYINN-QCDEQCNTAECLFDNFECQRNSKT--CKYDKYCADHFKDNHCDQGCNSEECGWDGLDCASDQPENLAEGTLIIVVLLPPEQLLQDSRSFLRALGTLLHTNLRIKQDSQGALMVYPYFGEKSAAMKKQKMTRRSLPEEQEQEQEVIGSKIFLEIDNRQCVQDSDQCFKNTDAAAALLASHAIQGTLSYPLVSVFSELESPRNAQLLYLLAVAVVIILFFILLGVIMAKRKRKHGFLWLPEGFTLRRDSSNHKRREPVGQDAVGLKNLSVQVSEANLIGSGTSEHWVDDEGPQPKKAKAEDEALLSE-DDPIDRRPWTQQHLEAADIRHTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSD-----LSDEDED--AEDSSANIITDLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITDHMDRLPRDVARDRMHHDIVRLLDEYNVTPSP---PGTVLTS-ALSPVLCGPNRS--FLSLKHTPMGKKARRPNTKSTMPTSLPNLAKEAKDAKGSRRKKCLNEKVQLSESSVTLSPVDSLESPHTYVSDATSSPMITSPGILQASPTPLLAAAAPAAPVHTQHALSFSNLHDMQPLAPGASTVLPSVSQLLSHHHIAPPGSSSAGSLGRLHPVPVPADWMNRVEMNETQYSEMFGMVLAPAEGAHPGIAAPQSRPPEGKHMSTQREPLPPIVTFQLIPKGS-----------IAQAAGAPQTQSSCPPAVAGPLPSMYQIPEMPRLPSVAFPPTMMPQQEGQVAQTIVP--------TYHPFPASVGKYPTPPSQHSYASSNAAERTPSHGGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGG-------------GGGGQRGPGTHMSEPPHSN----MQVYA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1RCH4-1", "uniprot_id": "F1RCH4_DANRE", "id": "F1RCH4-1", "name": "", "aln": "MGQLPGVSSGGVILLLICFLKTSYALQCIDHEKPCVNG-TCVISSNGTHYCRCAPGFLGEYCHHSDPCNLLYCKNGGECKVSVAGVPGSPSCVCPLGFAGEHCEIQKNSTCYPNNPCTNGGKCLLLPNDQYKCQCALGWTGQHCEQEDACLSSPCANKGICNALPNREYSCTCAPGFHGSRCLNDTDECVDPLVCKNKGVCVNTIGSYRCNCQPGFTGLDCGSPYFPCSPSPCQNGGTCRQTTETTYVCHCLPGFNGTNCEVNIDDCPDHRCQNGATCMDGVNTYNCQCPPEWTGQFCTDDVDECRLQPNACQNGGTCSNTRNGYNCVCVNGWSGLDCSENIDDCAAEPCTAGSTCIDRVASFVCSCPPGKTGLLCHIDDACISNPCKMGAHCDTNPVNGKFSCNCPSGYKGSTCAEDIDECVIG-PNPCEHGGSCKNTEGSFTCNCAPGYTGPRCEQDINECGSNPCQNDATCLDQIGDYTCICMPGFDGTHCENDINECLSSPCLNNGRCLDQVSRFVCECPQGFTGETCQVDIDECASTPCHNGAKCLDRPNGYECECAEGFTGPLCMENINDCEPQPCHHGKCIDGIATFHCDCLPGYMGPICSEQIRECQSDPCQNGGRCVDMVNRYQCNCQPGTAGENCQINYDDCASNPCQHGTCEDGINEYKCVCEPGYTGERCADEINECSSNPCQSGGTCEDKVNGFKCKCPVGTYGPLCLSGADRCIRMPCRHGECIGKQEGYLCQCEPGWEGTNCDQEKNECLSNPCQNGGTCNDRLNDYTCVCARGFAGFNCEININECESNPCMNQGTCVDGVNSYVCHCKPPYTGKHCLEKLIPCASQPCQRRGVCQPSLDYTSYTCKCHSGWEGAQCTEDKDECKKSPCQNGARCVNIVGSYRCECPPGYSGDNCQTNIDDCSSNPCRNGGTCVDKVGRYLCECRAGFYGERCEEEVDECASNPCWNGGHCTDYVNSYTCQCPPGYDGINCERDIPDCTETSCLNNGTCVDGINHFSCRCRQGFSGQYCQFELNECDSHPCKNGGTCIDGLGTFHCNCPLMYNGKTCESMVNLCSQIKCQNGGTCIQKEINWRCSCQPGWTGLYCDIPSMSCHAVALNKGVAENMVCKHAGHCKNIGNTHQCECQKGYTGSYCETEIDECLSSPCRNGGTCVDYQGGYDCKCKAGFQGVNCEYNVNECQSNPCRNGGTCIDLINHFSCSCPPGTKGLQCEVDVDECAPEFGPRCKNGGQCVDGVGRYTCNCPPGFAGEHCEGDVNECRSGPCYSPGTIDCVPLINSYQCRCRLGYTGQRCESMVDLCQSKPCHNNGRCTTNSSSVHGYICTCPPGFSGFNCGNYEMFPCASLRCLNGGQCVEIKSRPQCHCPVGFTGTHCEMLTNHCVCQNGGTCMPD-ESNKFSCRCPPGFSGETCQET-------PPSCPYPDCEQRAGDKVCDLRCKNPECDWDGSDCTLHWDKPWKNCKASVSCPDLFHNGRCDPECNNAGCLFDSFECDKHSSVGICKYDKYCADHYANGHCNQGCNTEACGWDGLDCARDTPPKLANGTLVIVVLLQPKELLADLKGFLRSLGTLLHTNLQVKLDEHNKLMVYPFYRNEQNEIQNEIAAMKQRGK-RELENEIIGSRVHLEIDNRLCTQNSDECISSADQAAAFIAAEYLKSDLPYPIYSITTKPPKETGFNFLYLVAVAAAIILLILVLGVLAAKRKRKHGTLWLPDGFLPNKES---KRREPVGQDDFGMKSMQKPQ-DGGLLDCSSNHHWSEED-HLPKKPRMEDKPLLPVGVDGVDRREWTLQHHKAADIT------LTPPQADNDMESLDVNVKGPDGFTPLMLASLRNGSSPDCGSMLGEEEEESGADEPGTNVITDLIGQGASLNAQTDRTGETALHLAARYARADAAKRLLDAGADANAHDNMGRTPLHAAVAADAQGVFQILIRNRATDLDARMNDGTTPLILSARLAVEGMVEELVHCHADVNAVDDHGKSALHWAAAVNNVDATLVLLKNGANRDMQDNKEETPLFLAAREGSFEAAQILLDHYSNRDITDHLDRLPRDTAQERMHHDIVRLLDEYNLVHSPHSGPNHVGNGGGHSSMVCGTNGTGYILGMRPGPQGKKNRRAGGKANG--VAAGTAKDLKEMKAKRRKK------------------------PTGGEGPSVVPVTTAGGNVSRAAGGLSESSVTMSPVDSLESP---HSYAGEPVATSSTANSPPLLSSQSARPMLPPVSHMLG--QQQSWVGLSKHSYNGHMFSLMPHHQMS----AGHSGMQQHHSPGMSAP---MNVTMSREQLPPIVTFQMMPTGSGQSLLKQPQQGQMQAQGQNQPQAQHLHCSQG---MMYPIPDVSMQHSLSHALQHPSHAHNHTLQHGLPDGQARQVVSYQPRQSPVDKYPTPPSQHSYATAGSEGTTPGHPAQKPSEHPYLTPSPESPDPWSSSSPHSNSDWSDVTTSPTPLGNPHTMPPSCHTHIPEQAQLQPPSQAAQPTQSQQSQRSSVYA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * . .:: * :* .::**** . :**** ** *** :*:*. *******:* ***: *:*** * .: *..:* *. **:**.*: ... .*: ..** ***.* :*..* *:* * :*:**:.*: ***** ** * . *.::.. ::**.* .*: *.:* * :** * *:: *.*:* ***:*:* **** *.* *.**:**** ******** : *: *:*****:*:.** ******:*:****..*:********:***:*******:***** ************:* ..**.********* ********** .**.*********** * ** **:*****:*********: ** *****:**:: *.**.****: *:**:***.:. .*****.*.* **:*:* *:* **:***** ***** *:**********:**.:**:*****.*.*** ::*** *.**:***:*:*:*.** * ** **** .**:***:*:**** *****:*:******:** **** ** ***::*:*:*****:* *** :: * * *****.***:** ** *.** *.***:*:** *********:* **:**:******** ** * ****.*.***.**:**:** :*:**:****:.*.** : ****:* ** *.: * * * .:.*: ** **:* * .** * *:.** * **: :***************:: :*.* *.* :** *:**::**:** ****:*****.*.:..*.*** *****:* * **:.:**:. .**: : :: *::* * .**:* :** * *** ..** * . * * *** ******:** :*: :*:** :***:***:*:* *. : * * .** *::*: :::** *:** *** *:******** * .*:.*::**.:* :***:**:*.******** *** * **:* :* .::***.*:** * ***:*****::* *** *.**.*:::*****: *:* ***:*:: . :* * .** * ***: .:**. .* .:** : :*:*:* * * **** *:* ******** ::*** *.**::*.** *: *** *:* .*:*******:*:***.:**:********:***.*******:** ** ::*:** **:* *****:* :* *:*.* ******:****:*** *.** * *::**: * *.* * ** .:**::**:::*:* . ** *.* *:. *. .*:** ******* .* . .*..::* .* **:. * *:*.* .** **:**:* *: :. :**:*.* *.*. *: *.:* * ::* * :** *:. *:***.**:* :.** **.:.: * : ::* :** **.. ****.***: :*.. **********: :.**:****:* ********* * * :**:***:****: *::** * :.***:*********::* *.:. *****:: ::. :::: : :. * *:*: **::.****** *.*:**.*:..:* ***::*:. ::. *.**: *: :: . ::***:***..***::::***: ******** ****:** .::: ********* .*:*.:. :..*:. .:..** ::: *** : **:.**. * :*** ** ** :**** ******::::: *****:**** *********.*** *.:*:*: *::..:*:****: *****:******** ********:*****************:***** *********************.****************:********* **::*:***********************:***:***************************:***:*****::*******:******.*::**************:. ** *. * .. . *.::**.* : :*.:: * *** **.. *:. .. **: *: *..**** * ...: *: *: * :. :. : ::.. :**.: .: : : :*:* .::: *.: . * : : .* * * : * :. . * .. : :* * .* : :. * * ::: ** ********::*.** *. * *.*: . * ** **::. *::.. .: ..:. * :* :*:* :.*.************::.: **.* .: .************* ******** ************ * .* * :: ::*.:.: .***", "identical_positions": 1329, "similar_positions": 618, "identity": "52.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000330-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLV2-1", "uniprot_id": "TP4AP_MOUSE", "id": "Q9JLV2-1", "name": "Short transient receptor potential channel 4-associated protein", "aln": "MAAAPAAAGAGASRGRRLAATAAAWGGWGGRPRPGNILLQLRQGQLTGRGLVRAVQFTETFLTERDKLSKWSGIPQLLLKLYATSHLHSDFVECQSILKEISPLLSMEAMAFVTEDRKFTQEATYPNTYIFDLFGGVDLLVEILMRPTISIRGQKLKISDEMSKDCLSILYNTCVCTEGVTKRLAEKNDFVIFLFTLMTSKKTFLQTATLIEDILGVKKEMIRLDEVPNLSSLVSNFDQQQLANFCRILAVTISEMDTGNDDKHTLLAKNAQQKKSLSLGPSAAEINQAALLSIPGFVERLCKLATRKVSESTGTASFLQELEEWYTWLDNALVLDALMRVANEESEHNQAPTVFPSLGTSEEGGLPHTSARAQLPQSMKIMHEIMYKLEVLYVLCVLLMGRQRNQVHRMIAEFKLIPGLNNLFDKLIWRKHSASALVLHGHNQNCDCSPDITLKIQFLRLLQSFSDHHENKYLLLNNQELNELSAISLKANIPEVEAVLNTDRSLVCDGKRGLLTRLLQVMKKEPAESSFRFWQARAVESFLRGTTSYADQMFLLKRGLLEHILYCIVDSECKSRDVLQSYFDLLGELMKFNVDAFKRFNKYINTDAKFQVFLKQINSSLVDSNMLVRCVTLSLDRFENQV-DMKVAEVLSECRLLAYISQVPTQMSFLFRLINIIHVQTLTQENVSCLNTSLVILMLARRKERLPLYLRLLQRMEHSKKYPGFLLNNFHNLLRFWQQHYLHKDKDSTCLENSSCISFSYWKETVSILLNPDRQSPSALVSYIEEPYMDIDRDFTEE---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TEL6-1", "uniprot_id": "TP4AP_HUMAN", "id": "Q8TEL6-1", "name": "Short transient receptor potential channel 4-associated protein", "aln": "MAAAPVAAGSGAGRGRRSAATVAAWGGWGGRPRPGNILLQLRQGQLTGRGLVRAVQFTETFLTERDKQSKWSGIPQLLLKLHTTSHLHSDFVECQNILKEISPLLSMEAMAFVTEERKLTQETTYPNTYIFDLFGGVDLLVEILMRPTISIRGQKLKISDEMSKDCLSILYNTCVCTEGVTKRLAEKNDFVIFLFTLMTSKKTFLQTATLIEDILGVKKEMIRLDEVPNLSSLVSNFDQQQLANFCRILAVTISEMDTGNDDKHTLLAKNAQQKKSLSLGPSAAEINQAALLSIPGFVERLCKLATRKVSESTGTASFLQELEEWYTWLDNALVLDALMRVANEESEHNQASIVFPPPGASEENGLPHTSARTQLPQSMKIMHEIMYKLEVLYVLCVLLMGRQRNQVHRMIAEFKLIPGLNNLFDKLIWRKHSASALVLHGHNQNCDCSPDITLKIQFLRLLQSFSDHHENKYLLLNNQELNELSAISLKANIPEVEAVLNTDRSLVCDGKRGLLTRLLQVMKKEPAESSFRFWQARAVESFLRGTTSYADQMFLLKRGLLEHILYCIVDSECKSRDVLQSYFDLLGELMKFNVDAFKRFNKYINTDAKFQVFLKQINSSLVDSNMLVRCVTLSLDRFENQV-DMKVAEVLSECRLLAYISQVPTQMSFLFRLINIIHVQTLTQENVSCLNTSLVILMLARRKERLPLYLRLLQRMEHSKKYPGFLLNNFHNLLRFWQQHYLHKDKDSTCLENSSCISFSYWKETVSILLNPDRQSPSALVSYIEEPYMDIDRDFTEE---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P2D2-1", "uniprot_id": "A0A8M1P2D2_DANRE", "id": "A0A8M1P2D2-1", "name": "", "aln": "--MATRGPGFSRTQTRR------------GKP-CKNIFHKIRQGQVTGEGLTRGSQVPVALLEERDKRAQWQGIPVLLRRLHKSSHPNSDLSKIHSIVMELSSLLSMEAISFVTEERKMPQESISPNTYTFDLFGGVDLFMEILMRPTLTIQQNTPTMSDDLIKDCLSVLYNCCICTEGVTKSLAAREDFVMYLFTLMSNKKVFLQTATLIEDILSVRKEIIQLEEIPNLDSLVQSFNQQQLANFCRILSVTISEPDVGVDDKHTLLARSTQQKT--STCPSHAENNQVALLNIPGFIERLCKLATRKVTEAA-DASARLELEDWHSWLDNALVLDTLMQLAIEEAEQ-------SSTESSDESSLSSSPLRHRLPQSMKIVHEIMYKVEVLYVLCVLLMGRQRNQVHRMLAEFKLIPGLNNLFDKLIWRKQ-PFGHILHRQNQSCDCSPEISFKIQFLRLLQSFSDHHENKYLLLSGQELNELSDIYLNANIFEMEALNNTDRNLVCDGKKGLLTRLISVMKKEPIDSSFRFWQARAVESFLRGTPSYADQVFLLRRGLLEHILYCIIDSGCKSHDVLQSYFDLLGELMKFNIDAFKRFNKYVTTEEKFQMFLTQINSSLVDSNMLVRCIVLSLDRFENETNDVKVVEVFSECRLLSYMAQVENRLLFLLRLISIINVQTLTQENVSCLNTSLVILMLARRRGKLPLYLSALREKEYSEKYPGCLLNNFHNLLRFWQHHYLNKDKDSTCLENSSCIPFTYWKETVSVLLGSGRSSRCAIATYIDEPYRDLDRDFMELSLETERTLFTSQTHPACGYNS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. ..* . : ** *:* **: ::****:**.**.*. *.. ::* **** ::*.*** ** :*: :** :**: : :.*: *:*.******::****:**:.**: **** *********::*******::*: :. .:**:: *****:*** *:******* ** ::***::*****:.**.************.*:**:*:*:*:***.***..*:***********:***** *.* ********:.:***. * ** ** **.***.****:***********:*:: ** ***:*::*********:**::* **:*: .. :*:*..*. :. * :*******:******:*********************:********************: . . :** :**.*****:*::**********************..******* * *:*** *:**: ****.******:******:.****** :******************.*****:***:***********:** ***:*****************:*********:.*: ***:**.***************:.********:. *:**.**:******:*::** .:: **:***.**:************************: :***** *:. *:*:**** *************:***:**************.*:*******:**...*.* .*:.:**:*** *:**** * ", "identical_positions": 538, "similar_positions": 167, "identity": "65.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000330-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P30305-1", "uniprot_id": "MPIP2_HUMAN", "id": "P30305-1", "name": "M-phase inducer phosphatase 2", "aln": "MEVPQPEPAPGSALSPAGVCG-GAQRPGHLPGLLLGSHG-----LLGSPVRAAASSPVTTLTQTMHDLAGLG--SETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSEAGSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSP--DRKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKTLEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEE-QQEAEEPKARVLRSKSLCHDEIENLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETMVALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQDQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A5N7-1", "uniprot_id": "B8A5N7_DANRE", "id": "B8A5N7-1", "name": "M-phase inducer phosphatase", "aln": "MDIDMVPGDVSPVYDPFSTGPESALGAPRFTLPELGARGSPCMKSLASPGPMAVLSPVTNLALNMNNLAVLGGQCETPK------------RKKNLPLLKIP---SFASDAS--SDAGLGLECPSPLDSLDAEQKFEKAMQDATRAV-NEKMPIRRIHSLPLQFLGHSPNLR----SKELDPSRYGVWTHSHDSANKENMAEENFEFKKPSMPALRCRTRSTG---GSKDAFACRPNSAPALMLSPPPTNQPDSPNEISPFILRRPSLSCLQ-DDDDDDGFLEGLD-DVENDSEVPLGMDSLLTAPLVAKQIPETDS-PVIRCRPRGLFRSPSMPCAVGRIPLKRPERPQDENTPVRVKRRRSLAGTQVSTTEQEDVVHQVQRSKSFNHSQIERMLDTDPSNVIGDFTKAPALPTVQGKHQELKYITPEIMVKAMSGQFQDLVERLFVIDCRYPYEYEGGHIKGALNLHQEDQIEDYFLRSPILPDCPKKRVLLIFHCEFSSERGPRMCRYVRERDRFVNEYPNLHYPELYILKGGYKEFFQIHKAICEPQMYRPMLHEEFKEDLRKFRLKSRTWAGERSKRDMYSRLKKL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: ... .* .. .* . ::. **::* *.** *. ****.*: .*::** ** .**** * .:*.* : . *::*::* ***** ::.***:*. ***.**:*:* *:* : **::.***::*:*:::***** ** *: * * . . *:. *: ::.* ** * *: . *:: . . ::*** **.*** ** .* :: . :*:**: * * **: : * ::****:: *: *:::*. ** **:**::**** . * :. *: .: : *********:* * *** *****.:***: *****:: .: * *: :* ****: *.:**.:**:* ::***::** * **:****:****:** ** ::*:*.::*:::.::************** *:** * : *.::*:*** * . .***:*****************::***** **:**.*:***:*********** * :**** **** ** **::*:.****:*:******:*:: ***:. ", "identical_positions": 271, "similar_positions": 159, "identity": "45.85%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000330-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62952-1", "uniprot_id": "BLCAP_HUMAN", "id": "P62952-1", "name": "Apoptosis inducing factor BLCAP", "aln": "MYCLQWLLPVLLIPKPLNPALWFSHSMFMGFYLLSFLLERKPCTICALVFLAALFLICYSCWGNCFLYHCSDSPLPESAHDPGVVGT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62951-1", "uniprot_id": "BLCAP_MOUSE", "id": "P62951-1", "name": "Apoptosis inducing factor BLCAP", "aln": "MYCLQWLLPVLLIPKPLNPALWFSHSMFMGFYLLSFLLERKPCTICALVFLAALFLICYSCWGNCFLYHCSDSPLPESAHDPGVVGT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62950-1", "uniprot_id": "BLCAP_RAT", "id": "P62950-1", "name": "Apoptosis inducing factor BLCAP", "aln": "MYCLQWLLPVLLIPKPLNPALWFSHSMFMGFYLLSFLLERKPCTICALVFLAALFLICYSCWGNCFLYHCSDSPLPESAHDPGVVGT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9IB61-1", "uniprot_id": "BLCAP_DANRE", "id": "Q9IB61-1", "name": "Apoptosis inducing factor BLCAP", "aln": "MYCLQWLLPVLLIPKPLNPALWFNHSMFMGFYLLSFLLERKPCTICALVFLAALFLICYSCWGNCFLYHCHDSPLPDSAHDPSIVGT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3L0-1", "uniprot_id": "Q9V3L0_DROME", "id": "Q9V3L0-1", "name": "", "aln": "MYCLQCLLPVLLIPKPSNPALMETHVMFIVLYLVGFFLERKPCTICSLVFLTAVSLICYSGVGNCIFWGNCEGHQCENG--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** ********** **** .* **: :**:.*:*********:****:*: ***** ***::: :. :.. ", "identical_positions": 47, "similar_positions": 17, "identity": "54.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000330-8", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P38432-1", "uniprot_id": "COIL_HUMAN", "id": "P38432-1", "name": "Coilin", "aln": "MAAS--ETVRLRLQFDYPPPATPHCTAFWLLVDLNRCRVVTDLISLIRQRFGFSSGAFLGLYLEGGLLPPAESARLVRDNDCLRVKLEERGVAENSVVISNGDINLSLRKAKKRAFQLEEGEETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVSVCSKESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGFSLTPSKGKTSG-TTSSSSDSSAESDDQCLMSSSTPECAAGFLKTVGLFAGRGRPGPGLSSQTAG---AAGWRRSGSNGGGQ-APGASPSVSLPASLGRGWGREENLFSWKGAK-GRGMRGRGRGRGHPVSCVVNRSTDNQRQQQLNDVVKNSSTIIQN-PVETPKKDYSLLPLLAAAPQVGEKIAFKLLELTSSYSPDVSDYKEGRILSHNPETQQVDIEILSSLPALREPGKFDLVYHNENGAEVVEYAVTQESKITVFWKELIDPRLIIESPSNTSSTEPA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S7K8-1", "uniprot_id": "B0S7K8_DANRE", "id": "B0S7K8-1", "name": "", "aln": "MATSSLNTARVRLYFDYPPPATPECRMCWLLVDLNKCRVVADLSSIIKEKFGYSRKTILDLFIEECYLPSAESIYIVRDNDSVRVKVS-------CPVQVNG---------------------TEAEAQNSKSKKRGRED------------ETQTCDGLSKKQKQDNAQMNGLGPDEDEKKKKKKKKKKKKKEVKESITKPATP--QKSTAALSTKTKSKSTSAVASSDKTNRTKNHKPAS--SSSDSSEDESQKKAPPPKP-KPSKKPCVAAQKESTDSSSSDETEKLKSSIPLPITPKPSSSTSKLQTPQQRESSSSSSSSPIIKNSQAAGQSSSTTQKSLQPVSSSVPKKPQDEGESSSSDESEIELVIKKPNLQGLGLRIAGVSPGFGEAAGRGRGNAQGQERGRGRGANRGSGRGGFSRARGTPWKQNFHYSYENEERQKPEDSLTNESFILQNPPELAPKRDYATLPLLAAPPAVGQKIAFKLLELTENYTPEVSDYKEGKILAFNPQTKVTELELLSRPQAPAEPGKFDLVYQNPDGSERVEYAVTQGSQLTERWDSLLEPRLIVENAK--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* :*.*:** *********.* *******:****:** *:*:::**:* ::*.*::* **.*** :*****.:***:. . * ** **.:.: **.: :.**: :: * : :***:*:.* * *::*: *:*. ***:* * *:. .:* :* * . . : .* . ** * *::*. . . .* *.*.***.** .:: . * * : :. :::* .*: *..: : * .:: *.*. * :.** :*. ****.**: .:. :..:.. : *:.*. . : . * **.: ::.. :* * .*.**... .*. *** .: :: :**: * * * .*.** * . .: * :*:.:*: :* :.*.* *:** * :**:**: ******.* **:**********..*:*:*******:**:.**:*: .::*:** * *********:* :*:* ******* *::* *..*::****:*... ", "identical_positions": 214, "similar_positions": 174, "identity": "36.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000330-9", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88777-1", "uniprot_id": "PSN2_RAT", "id": "O88777-1", "name": "Presenilin-2", "aln": "--MLTFMASDSE----EEVCDERTSLMSAE---SPTSRSCQD----SRPGPEDGENTAQWRSQENEDDCEEDPDHYACSGV-PGRPSG--LEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQ-LIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVFKTYNVAMDYPTLFLAVWNFGAVGMVCIHWKGPLVLQQAYLIVISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLD-PSSQGALQLPYDPEMEEDSYDSFGEPSYPEAFEAP------------------------------------------------------------------------------QPGYPGEEPEEEEERGVKLGLGDFIFYSVLVGKAAATGNGDWSTTLACFIAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61144-1", "uniprot_id": "PSN2_MOUSE", "id": "Q61144-1", "name": "Presenilin-2", "aln": "--MLAFMASDSE----EEVCDERTSLMSAE---SPTSRSCQE----GRPGPEDGESTAQWRTQESEEDCEEDPDRYACSGA-PGRPSG--LEEELTLKYGAKRVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQ-LIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLFLAVWNFGAVGMVCIHWKGPLVLQQAYLIVISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLD-PSSQGALQLPYDPEMEEDSYDSFGEPSYPEAFEAP------------------------------------------------------------------------------LPGYPGEELEEEEERGVKLGLGDFIFYSVLVGKAAATGNGDWNTTLACFIAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49810-1", "uniprot_id": "PSN2_HUMAN", "id": "P49810-1", "name": "Presenilin-2", "aln": "--MLTFMASDSE----EEVCDERTSLMSAE---SPTPRSCQE----GRQGPEDGENTAQWRSQENEEDGEEDPDRYVCSGV-PGRPPG--LEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQ-LIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLD-PSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPP------------------------------------------------------------------------------LTGYPGEELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90ZE4-1", "uniprot_id": "PSN2_DANRE", "id": "Q90ZE4-1", "name": "Presenilin-2", "aln": "-----MNTSDSE----EDSYNERSALVQSE---SPTVPSYNQDNAMSLPQDTDSKRSGAVRSRSASGSGDAGP---VDRER-ADTPDG--EEEELTLKYGAKHVIMLFIPVTLCMVVVVATIKSVSFYTEKSGQRLIYTPFEEDPNSVGQRLLNSVLNTLVMISVIVFMTIILVLLYKYRCYKFIHGWLILSSLMLLFWFSFMYLGEVFKTYNVAMDYPTLLMIIWNFGVVGMICIHWKGPLRLQQAYLIVISALMALIFIKYLPEWSAWVILGAISIYDLIAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWMVGMADSNNPDSAGERRRSGGGVRTQE-----GVESEHDAPQAG------------------------------------------------------------------------------RRQYSAEE-DLEEDRGVKLGLGDFIFYSVLVGKAAATG-GDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFSTDNLVRPFMDSLAAHQYYI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O02194-1", "uniprot_id": "PSN_DROME", "id": "O02194-1", "name": "Presenilin homolog", "aln": "MAAVNLQASCSSGLASEDDANVGSQIGAAERLERPPRRQQQRNNYGSSNQDQPDAAILAVPNVVMREPCGSRPSRLTGGGGGSGGPPTNEMEEEQGLKYGAQHVIKLFVPVSLCMLVVVATINSISFYNSTDVY-LLYTPFHEQSPEPSVKFWSALANSLILMSVVVVMTFLLIVLYKKRCYRIIHGWLILSSFMLLFIFTYLYLEELLRAYNIPMDYPTALLIMWNFGVVGMMSIHWQGPLRLQQGYLIFVAALMALVFIKYLPEWTAWAVLAAISIWDLIAVLSPRGPLRILVETAQERNEQIFPALIYSSTVVYALVNTVTPQQSQATASSSPSSSNSTTTTRATQNSLASPEAAAASGQRTGNSHPRQNQRDDGSVLATEGMPLVTFKSNLRGNAEAAGFTQEWSANLSERVARRQIEVQSTQSGNAQRSNEYRTVTAPDQNHPDGQEERGIKLGLGDFIFYSVLVGKASSYG--DWTTTIACFVAILIGLCLTLLLLAIWRKALPALPISITFGLIFCFATSAVVKPFMEDLSAKQVFI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* *. *: : : : :* *. . : . . . * . .. * *** *****::** **:**:***:******:*: **.... *:**** *:. . . :: .:: *:*:::**:*.**::*::*** ***::******:**:**** *:::** *::::**:.***** :: :****.***:.***:*** ***.***.::*****:********:**.:*.***::**:***.*:****:********** *********::*: : : .. . . . : :. . :. : :*:**:*****************:: * **.**:***:**************:::**************:* *:*. :*:***: *:::* :*", "identical_positions": 210, "similar_positions": 121, "identity": "38.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000403-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70239-1", "uniprot_id": "AXIN1_RAT", "id": "O70239-1", "name": "Axin-1", "aln": "--MNVQEQG--FPLDLGASFTEDAPRPPVPGEEGELVSTDSRPVNHSFCSGKGTSIKSETSTATPRRSDLDLGYEPEGSASPTPPYLRWAESLHSLLDDQDGISLFRTFLKQEG--CADLLDFWFACSGFRKLEPCDSNEEKRLKLARAIYRKYILDSNGIVSRQTKPATKSFIKDCVMKQQIDPAMFDQAQTEIQSTMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGMSGYLPTLNEDEEWKCDQDADEDDGRDSVPPSRLTQKLLLETAAPRAPSSRRYNEGRELRYGSWREPVNPYYVNSGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIPRTYRMPKEIRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDGEMPSGP-MASHKLPSVPAWHHFPPRYVDMGCSG--LRDAHEENP-ESILDEHVQRVMRTPGCQSPGPG-----HRSPDSGHVAKT-AVLGGTASGHGKHAPKLGLKLDSAGLHHHRHVHHHVHHNSARPKEQMEAEAARRVQSSFSWGPETHGH-AKPRSYSESTGTNPSAGD-LAFGGKASAPSKRNTKKAESGKNASAEVPSTTEDAEKNQKIMQWIIEGEKEISRHRKAGHGS-SGMRKQQAHESSRPLSIERPGAVHPWVSAQLRNSVQPSHLFIQDPTMPPNPAPNPLTQLEEARRRLEEEEKRANKLPSKQR------------------------------------TKSQRKAGGGSAPPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAILPVFEEKIIGKVEKVD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35625-1", "uniprot_id": "AXIN1_MOUSE", "id": "O35625-1", "name": "Axin-1", "aln": "--MNVQEQG--FPLDLGASFTEDAPRPPVPGEEGELVSTDSRPVNHSFCSGKGTSIKSETSTATPRRSDLDLGYEPEGSASPTPPYLRWAESLHSLLDDQDGISLFRTFLKQEG--CADLLDFWFACSGFRKLEPCDSNEEKRLKLARAIYRKYILDSNGIVSRQTKPATKSFIKDCVMKQQIDPAMFDQAQTEIQSTMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGMSGYLPTLNEDEEWKCDQDADEDDGRDPLPPSRLTQKLLLETAAPRAPSSRRYNEGRELRYGSWREPVNPYYVNSGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESIQVNGRVPLPHIPRTYRMPKEIRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDGEMPSGP-MASHKLPSVPAWHHFPPRYVDMGCSG--LRDAHEENP-ESILDEHVQRVMRTPGCQSPGPG-----HRSPDSGHVAKT-AVLGGTASGHGKHVPKLGLKLDTAGLHHHRHVHHHVHHNSARPKEQMEAEVARRVQSSFSWGPETHGH-AKPRSYSENAGTTLSAGD-LAFGGKTSAPSKRNTKKAESGKNANAEVPSTTEDAEKNQKIMQWIIEGEKEISRHRKAGHGS-SGLRKQQAHESSRPLSIERPGAVHPWVSAQLRNSVQPSHLFIQDPTMPPNPAPNPLTQLEEARRRLEEEEKRANKLPSKQRYVQAVMQRGRTCVRPACAPVLSVVPAVSDLELSETETKSQRKAGGGSAPPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15169-1", "uniprot_id": "AXIN1_HUMAN", "id": "O15169-1", "name": "Axin-1", "aln": "--MNIQEQG--FPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEG--CADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPTLNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREPVNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAG--LRDAHEENP-ESILDEHVQRVLRTPGRQSPGPG-----HRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVHHSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGVACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGS-SGTRKPQPHENSRPLSLE-----HPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKRASRAPSKQRYVQEVMRRGRACVRPACAPVLHVVPAVSDMELSETETRSQRKVGGGSAQPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P57094-1", "uniprot_id": "AXIN1_DANRE", "id": "P57094-1", "name": "Axin-1", "aln": "MSMSVNEKGICYLPDLGSSFTEDAPRPPVPGEEGDLVSSDGRQYNHSFYSSKSDSLKNEASIATPRRPDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGIHLFRTFLKQEE--CADMLDFWFACSGFRKQEANDGNE-KMLKLAKAIYKKYILDNNGIVSRQIKPATKSFIKDCVTKLHIDPAMFDQAQTEIQTMMEENTYPLFLKSDIYLEYTRTGGESPKLFSDQSSVSGNGKVLPGYLPTVIEDVEWRCDQEEEQIAESDPTPSNRLTQKLPLETVPQRVANSKRYQDNREYRHASWREPVNPYYVNSGYALAPATSANDSEQQSMSSDADTLSLTDSSVDGVPPYRYRKPHRREIHESAKVNGRVPLPHIPRTNRIPKDIHVEPEKFAAELISRLEGVLREREAQEKLEERLKRVRLEEEGDDADISTGPSLANHRVPPAVHVQHYGGRYSEMSYNGLQLRDAHEENP-ESILDEHVQRVMKTPGCQSPGTGRHSPKSRSPDGLPAGKIPGLMMPLSGGQGKHQARQGPKGEAAHLHHHKHIHHTHYAAAGKPKEQAEAEAAR-MHGGFAWNTEQHHYGPKSRNYADGMSVGPNTMDPMGYSSKGSTLSKRPVRKGEDGRNFEMREPLPADDMERNQKILQWMMEGEKEAGRYKRGPYGSISGPKKAQGHEPARPSSVERLGAVHPWVTAQLRNNVQPSHPFIQDPTMPPNPAPNPLTQLEEARRRLEEERRKSGTLQAKQR------------------------------------HKNMKKQ------PCENITVAYYFRGEPIPYRTSVKGRIVTLGQFKELLTKKGSYKYYFKKVSYEFDCGVVFEEVREDDAILPIFEEKIIGKVEKVD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V407-1", "uniprot_id": "AXN_DROME", "id": "Q9V407-1", "name": "Axin", "aln": "--MSGHPSG----IRKHDDNECSGPRPPVPGEESRVKKMTEG--------------------------------VADTSKNSSPSYLNWARTLNHLLEDRDGVELFKKYVEEEAPAYNDHLNFYFACEGLKQQTD----PEKIKQIIGAIYR-FLRKSQLSISDDLRAQIKAIKTN--PEIPLSPHIFDPMQRHVEVTIRDNIYPTFLCSEMYILYIQQMSAQQERCTSSG---ATGSGSAGSSGSGGSSLAGACALPPTTASGKQQLPQLVPPGAFINLPVSSVSGPPAGTCSASGSVYGPSTSASSSGSISATDTLPRSSTLPTLHEDSVLSLCDDFEKVQMQEGGGS---LGSGSVGAGARAPDYPIRLTRDLLIATQKRRLEIRPPG---AHGYVYNPSTTNTSYVPNSRVDSERASVSSGGRTDSDTMSISSCSMDGRPYIQRRHSSTESKAIRQSAMANKETNTFQVIPRTQRLHSNEHRPLKEEELVSLLIP------KLEEVKRKRDLEERARERNPGAALLTNERSSASDRAFAEAIREKFALDEDNDQDILDQHVSRVWKDQTPHRSPGTMSPCPPIPSRRRTATHDSGMVSDGAMSLSGHSMKHSKSMPDHSSCSRKLTNKWPSMNTDSGISMFSADTVTKYKDASSRSGSSTASKLEEAKRRLEDEPRRSRRYAQPPMQHLSQQPLASFSSSSSGGSISLPHQPPPLPAKPP-----------------------------------------------------------------------------ETIVVFSFCEEPVPYRIKIPGTQPTLRQFKDYLPRRGHFRFFFKTHCEDPDSPVIQEEIVNDSDILPLFGDKAMGLVKPSD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : .* . ..*********. : . .: * ..:*.**.**.:*: **:*:**: **:.::::* * *:*:*** *::: * :: ***: :: ..: :* : :. *:: .. : :.* :** * .:: :.:* ** ** *::*: * : . . : :... ..*. .* : .. * : * . : ... . . :.. .. .. :.: :*. ::: .::*: * .* :. .: . .* . . .: . *:. : * : ::: * : . . . .:.:::.. * . :. . .. : : . . ::.: * . *..: :* :: * : : . * . . . : * . :. . :* :.. : : . .* : . : . :. ..: .* :.. .:. . * * . : : : :. .* .. . :: .* *. * . . ..* *. * ** ..:* . *.: * **:*** : * ** ***: *.::* ::::**. . : *. *: **: :*. :**:* :* :* *: *", "identical_positions": 114, "similar_positions": 240, "identity": "12.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000403-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70240-1", "uniprot_id": "AXIN2_RAT", "id": "O70240-1", "name": "Axin-2", "aln": "MSSAVLVTLLPDPSSSFREDAPRPPVPGEEGETPPCQPS-VGKVQSTKPMP------VSSNARRNEDGLGEPEGRASPDSPLTRWTKSLHSLLGDQDGAYLFRTFLEREK--CVDTLDFWFACNGFRQMNLKDTKTLRVAKAIYKRYIENNSVVSKQLKPATKTYIRDGIKKQQIGSVMFDQAQTEIQAVMEENAYQVFLTSDIYLEYVRSGGENTAYMSNGGLGSLKVLCGYLPTLNEEEEWTCADLKCKLSPTVVGLSSKTLRATASVRSTETAENGFRSFKRSEPVNPYHVGSGYVFAPATSANDSELSSDALTDDSMSMTDSSVDGIPPYRMGSKKQLQREMHRSVKANGQVSLPHFPRTHRLPKEMTPVEPAAFAAELISRLEKLKLELESRHSLEERLQQIREDEEKEGSEQALSSRDGAPVQHPLALLPSGSYEEDPQTILDDHLSRVLKTPGCQSPGVGRYSPRSRSPDHH--HHHHQQCHALLPTGGKLPPEAA----CPLLGGKSFLTKQTTKHVHHHYIHHHAVPKTKEEIEAEATQRVRCLCPGGTDYYCYSKCKSHSKPPEPLPG-EQFCGSRGGTLPKRNTKGTEPGLALPAREGGMSSAAGAPQLPGEEGDRSQDVWQWMLESERQSKSKPHSTQSIRKSYPLESARAPPGERVSRHHLLG-ASGHPRSAARAHPFTQDPAMPPLTPPNTLAQLEEACRRLAEVSKPQKQRCCVASQQRDRNHPATGQAGPTSFSNPSLASEDHKEPKRLASVHALQASELIVTYFFCGEEIPYRRMLKAQSLTLGHFKEQLSKKGNYRYYFKKASDEFACGAVFEEIWDDETVLPMYEGRILGKVERID", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88566-1", "uniprot_id": "AXIN2_MOUSE", "id": "O88566-1", "name": "Axin-2", "aln": "MSSAVLVTLLPDPSSSFREDAPRPPVPGEEGETPPCQPS-VGKVQSTKPMP------VSSNARRNEDGLGEPEGRASPDSPLTRWTKSLHSLLGDQDGAYLFRTFLEREK--CVDTLDFWFACNGFRQMNLKDTKTLRVAKAIYKRYIENNSVVSKQLKPATKTYIRDGIKKQQIGSVMFDQAQTEIQAVMEENAYQVFLTSDIYLEYVRSGGENTAYMSNGGLGSLKVLCGYLPTLNEEEEWTCADLKCKLSPTVVGLSSKTLRATASVRSTETAENGFRSFKRSDPVNPYHVGSGYVFAPATSANDSELSSDALTDDSMSMTDSSVDGVPPYRMGSKKQLQREMHRSVKANGQVSLPHFPRTHRLPKEMTPVEPAAFAAELISRLEKLKLELESRHSLEERLQQIREDEEKEGSEQALSSRDGAPVQHPLALLPSGSYEEDPQTILDDHLSRVLKTPGCQSPGVGRYSPRSRSPDHHHQHHHHQQCHTLLPTGGKLPPVAA----CPLLGGKSFLTKQTTKHVHHHYIHHHAVPKTKEEIEAEATQRVRCLCPGGTDYYCYSKCKSHPKAPEPLPG-EQFCGSRGGTLPKRNAKGTEPGLALSARDGGMSSAAGAPQLPGEEGDRSQDVWQWMLESERQSKSKPHSAQSIRKSYPLESACAAPGERVSRHHLLG-ASGHSRSVARAHPFTQDPAMPPLTPPNTLAQLEEACRRLAEVSKPQKQRCCVASQQRDRNHSAAGQAGASPFANPSLAPEDHKEPKKLASVHALQASELVVTYFFCGEEIPYRRMLKAQSLTLGHFKEQLSKKGNYRYYFKKASDEFACGAVFEEIWDDETVLPMYEGRILGKVERID", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2T1-1", "uniprot_id": "AXIN2_HUMAN", "id": "Q9Y2T1-1", "name": "Axin-2", "aln": "MSSAMLVTCLPDPSSSFREDAPRPPVPGEEGETPPCQPG-VGKGQVTKPMP------VSSNTRRNEDGLGEPEGRASPDSPLTRWTKSLHSLLGDQDGAYLFRTFLEREK--CVDTLDFWFACNGFRQMNLKDTKTLRVAKAIYKRYIENNSIVSKQLKPATKTYIRDGIKKQQIDSIMFDQAQTEIQSVMEENAYQMFLTSDIYLEYVRSGGENTAYMSNGGLGSLKVVCGYLPTLNEEEEWTCADFKCKLSPTVVGLSSKTLRATASVRSTETVDSGYRSFKRSDPVNPYHIGSGYVFAPATSANDSEISSDALTDDSMSMTDSSVDGIPPYRVGSKKQLQREMHRSVKANGQVSLPHFPRTHRLPKEMTPVEPATFAAELISRLEKLKLELESRHSLEERLQQIREDEEREGSELTLNSREGAPTQHPLSLLPSGSYEEDPQTILDDHLSRVLKTPGCQSPGVGRYSPRSRSPDHH--HHHHSQYHSLLPPGGKLPPAAASPGACPLLGGKGFVTKQTTKHVHHHYIHHHAVPKTKEEIEAEATQRVHCFCPGGSEYYCYSKCKSHSKAPETMPS-EQFGGSRGSTLPKRNGKGTEPGLALPAREGGAPGGAGALQLPREEGDRSQDVWQWMLESERQSKPKPHSAQSTKKAYPLESARSSPGERASRHHLWGGNSGHPRTTPRAHLFTQDPAMPPLTPPNTLAQLEEACRRLAEVSKPPKQRCCVASQQRDRNHSATVQTGATPFSNPSLAPEDHKEPKKLAGVHALQASELVVTYFFCGEEIPYRRMLKAQSLTLGHFKEQLSKKGNYRYYFKKASDEFACGAVFEEIWEDETVLPMYEGRILGKVERID", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P57095-1", "uniprot_id": "AXIN2_DANRE", "id": "P57095-1", "name": "Axin-2", "aln": "----MNRTLTDPMVSSFREDDPRPPVPGEEGETTCHHPSKLAMMRPKDPVKTIMADLRCSTARRDEDGLGEPEGSASPDSPLARWTKSLHFLLGDQDGAQLFRAYLEREK--CVDTLDFWFACNGFRQMDLKDTKTHRVAKAIYKRYIENNSIVAKQLKPATKTFIRDNIKRQQIDSAMFDQAQMEIQTAMEENAYQMFLTSDIYLEYVRTGCENPSHVNPNGLGGLKLVCGYLPTLNEEEEWSCNDFKAKALATVVGLSAKTLRSPP-LRAVEALEKGYRSYRRSDPGNPNRFTSGYSFAPATSANDSEVSSDALTDDSMSMTDSSVDAIPPYKLGSKKQLQREMQRNMRMNGQVSLPPFPRTRRPPKEMTPVEPAAFAAQLIARLERLKREQETMSSLEERLQQIQEEEERDESEMSSSS-----ASHSLPLLPPGTCEEDPQAILDEHLSRVLKTPGCQSPGLLRHSPRSRSPEQR-----------PLPRGG-LSTRSQSSSMNGYVPAKTFISRQSTKHIHHHYIHHHAGPKSKEQIEVEATQRVQCLCHGTSECCTAPYIRSRSLGRDQCASPAEVALGHSSTLSKRLCKSGEE-VNMEGLEN------SLLQLPADSTDRSQNVWQWILESDRQTKHKPHSTQNVKKSHSLEPTR-------THTWGGGGSSGHLRAHQPAHPFVQDPAMPPLPPPNTLAQLEEARRRLEEVSKPSKQRHSTSSLQRDKSHPVPVQNGSSAFP-----MDERKDPKKMSGCHSSLGSETVVTYFFCGEEIPYRRMMKTHSLTLGHFKEQLRKKGNYRYFFKRASDEFECGAVFEEVWDDCTVLPMYEGKILGKVDRMD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V407-1", "uniprot_id": "AXN_DROME", "id": "Q9V407-1", "name": "Axin", "aln": "---MSGHPSGIRKHDDNECSGPRPPVPGEE-----------------------------SRVKKMTEGVADTSKNSSP--SYLNWARTLNHLLEDRDGVELFKKYVEEEAPAYNDHLNFYFACEGLKQQTDPE-KIKQIIGAIYRFLRKSQLSISDDLRAQIKAIKTN--PEIPLSPHIFDPMQRHVEVTIRDNIYPTFLCSEMYILYIQQMSAQQERCTSSGATGSGSAG------SSGSGGSSLAGACALPPTTASGKQQLPQLVPPGAFINLPVS-----SVSGPPAGTCSASGSVYGPSTSASSS---GSISATDTLPRSST----LPTLHEDSVLSLCDDFEKVQMQEGGGSLGSGS-----------VGAGARAPDYPIRLTRDLLIATQKRRLEIRPPGAHGYVYNPSTTNTSYVPNSRVDSERASVSSGGRTDSDTMSISSCSMDGRPYIQRRHSSTESKAIRQSAMANKET------NTFQVIPRTQRLHSNEHR--------------PLKEEELVSLLIPKLEEVKRKRDLEERARERNPGAALLTNERSSASDRAFAEAIREKFALDEDNDQDILDQHVSRVWKDQTPHRSPGTMSPCPPIPSRRRTATHDSGMVSDGAMSLSGHSMKHSKSMPDHSSCSRKLTNKWPSMN---------------TDSGISMFSADTVTKYKDASSRSGSSTASKLEEAKRRLEDEPRRSR-RYAQPPMQHLSQQPLASFSSSSSGGSISLPHQPPPLPAKPP--------ETIVVFSFCEEPVPYRIKIPGTQPTLRQFKDYLPRRGHFRFFFKTHCEDPDSPVIQEEIVNDSDILPLFGDKAMGLVKPSD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. . . ********* * .:: :*:.:.. :** . .*:::*: ** *:**. **: ::*.* * *:*:***:*::* : * :: ***: :.: ::.:*:. *: : . :.. :** * .:: .:.:* * ** *::*: *:: : . .* . .. . :. . .*... . : : . : . * * ** :.*:***..* .. : *::. :.: :*. : .* .* ::.: :* ** . * ..: *.: ** : ** * : . : : .. .: . * :.*. :* . :. :*. : :* .::. :* * . . :.: * : * *.::* .* :* . .: . : . : . . .* *. . . :. *:.. . .* :::* *. :. :* .: :. : *. ..: .. . ..* ::**** *** : .: : * . .. *: .:. . ..:. : * : . * :*.: ** * :*** : . ** :**: * ::*::*::** .:: . .: **: :* :**:: .: :* *. *", "identical_positions": 130, "similar_positions": 242, "identity": "15.2%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000405-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AGR6-1", "uniprot_id": "A0A8I6AGR6_RAT", "id": "A0A8I6AGR6-1", "name": "", "aln": "MDDQSRMLQTLAGVNLAGHSVQGGMALPPPPHGHEG-ADGDGRKQ-DIGDILHQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGVSGPEKGGGSAAAAAAAAASGGS------SDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQ----------VSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNS--------------------------GSSGSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGANSLYSPHNLNANGGWQDATTPSSVTSPTEGPGSVHSDTSN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35317-1", "uniprot_id": "PBX3_MOUSE", "id": "O35317-1", "name": "Pre-B-cell leukemia transcription factor 3", "aln": "MDDQSRMLQTLAGVNLAGHSVQGGMALPPPPHGHEG-ADGDGRKQ-DIGDILHQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGVSGPEKGGGSAAAAAAAAASGGS------SDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQ----------VSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNS--------------------------GSSGSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGANSLYSPHNLNANGGWQDATTPSSVTSPTEGPGSVHSDTSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40426-1", "uniprot_id": "PBX3_HUMAN", "id": "P40426-1", "name": "Pre-B-cell leukemia transcription factor 3", "aln": "MDDQSRMLQTLAGVNLAGHSVQGGMALPPPPHGHEG-ADGDGRKQ-DIGDILHQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGVSGPEKGGGSAAAAAAAAASGGS------SDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQ----------VSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNS--------------------------GSSGSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANGGWQDATTPSSVTSPTEGPGSVHSDTSN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B506-1", "uniprot_id": "A0A8M3B506_DANRE", "id": "A0A8M3B506-1", "name": "", "aln": "MDEQARIMQTLGGVSLAGHSVQGGMALPPP-HGHDG-TDGDGRKQ-DIGDILHQIMTITDQSLDEAQAKKHGLNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAAAGSP------TDNSIEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQGVGTTITVAQVSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAAAAAVQNSQTNSPTTPNSGFQMKDEEFQLDSAENKNTLLTNMFTGSSGSFNLPNSGDLFMSMQNLNGDSYQGAQVGANVQSQVDTLRHVISQTAGYNDVLGGNPMYSPHGLNGNGGWQDATTPSSVISPTEGPGSVHSDTSN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40427-1", "uniprot_id": "EXD_DROME", "id": "P40427-1", "name": "Homeobox protein extradenticle", "aln": "MEDPNRMLAHTG-----GMMAPQGYGLSGQDDGQNAGSENEVRKQKDIGEILQQIMSISEQSLDEAQARKHTLNCHRMKPALFSVLCEIKEKTVLSIRNTQEEEPPDPQLMRLDNMLIAEGVAGPEKGGGGAAAASAAAASQGGSLSIDGADNAIEHSDYRAKLAQIRQIYHQELEKYEQACNEFTTHVMNLLREQSRTRPITPKEIERMVQIIHKKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQASEILNEYFYSHLSNPYPSEEAKEELARKCGITVSQ----------VSNWFGNKRIRYKKNIGKAQEEANLYAAKKAAGASPYSMAGPPSGTTTPMMSPAP---------------------------PQDSMGYP-----------MGSGGYDQQQP--------------------YDNSMGG---YDPN--------------------------LHQDLSP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: *:: . * . * .*. .*::. ::.: *** ***:**:***:*::********:** ********************* ****.:***:*************:****:*******.****:****: . :**:**********:******* *****************************:******** ***:**************************************:*************************:**.***** ****************** **********.*. *: *. .. *.. :* . ...*:. * :....*: * *.: :*. *.*: :*.* * ", "identical_positions": 261, "similar_positions": 68, "identity": "54.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000405-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABZ3NN70-1", "uniprot_id": "A0ABZ3NN70_RAT", "id": "A0ABZ3NN70-1", "name": "", "aln": "MNRVVGEHSRGRTPHRQARNPGGRATLHPTAGSAGPGANPASPRPPRRSPPPPAAARPASPRPRLLPVPPLLPSSSSRSPPPAASLAPPSPSSLLSHTHPRLGLLSLSLRLHFLRRRGPGSPVGVPRRHPGSPLQCRGEPPKGAGRRVAGRGWGGGSSGPSEFGGEVTRRGEGRAGRGPQGPPPAMDERLLGPPPPGGGRGGLGLVGGEPG---------GPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGGG----VSPDNSIEHSDYRSKLAQIRHIYHSELEKYEQACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAVKTAVSVAQGGHSRTSSPTPPSSAGSGGSFNLSGSGDMFLGMPGLNGDSYPASQVESLRHSMGPASYGDNIGGGQIYSPREMRANGGWQEAVTPSSVTSPTEGPGSVHSDTSN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35984-1", "uniprot_id": "PBX2_MOUSE", "id": "O35984-1", "name": "Pre-B-cell leukemia transcription factor 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDERLLGPPPPGGGRGGLGLVGAEPG---------GPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGGG----VSPDNSIEHSDYRSKLAQIRHIYHSELEKYEQACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAVKTAVSVAQGGHSRTSSPTPPSSAGSGGSFNLSGSGDMFLGMPGLNGDSYPASQVESLRHSMGPGSYGDNIGGGQIYSPREIRANGGWQEAVTPSSVTSPTEGPGSVHSDTSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40425-1", "uniprot_id": "PBX2_HUMAN", "id": "P40425-1", "name": "Pre-B-cell leukemia transcription factor 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDERLLGPPPPGGGRGGLGLVSGEPG---------GPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGGG----VSPDNSIEHSDYRSKLAQIRHIYHSELEKYEQACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAVKTAVSVTQGGHSRTSSPTPPSSAGSGGSFNLSGSGDMFLGMPGLNGDSYSASQVESLRHSMGPGGYGDNLGGGQMYSPREMRANGSWQEAVTPSSVTSPTEGPGSVHSDTSN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40427-1", "uniprot_id": "EXD_DROME", "id": "P40427-1", "name": "Homeobox protein extradenticle", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDPNRMLAHTGG--------MMAPQ---------GYG--LSGQDDGQNAGSENEVRKQKDIGEILQQIMSISEQSLDEAQARKHTLNCHRMKPALFSVLCEIKEKTVLSIRNTQEEEPPDPQLMRLDNMLIAEGVAGPEKGGGGAAAASAAAASQGGSLSIDGADNAIEHSDYRAKLAQIRQIYHQELEKYEQACNEFTTHVMNLLREQSRTRPITPKEIERMVQIIHKKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQASEILNEYFYSHLSNPYPSEEAKEELARKCGITVSQVSNWFGNKRIRYKKNIGKAQEEANLYAAKKAA-----GASPYSMAGPPSGTTT----------------PMMS----PAPPQDSMGYPMGSGGYDQ-------QQPYDNSMGG-----YDPN-----------LHQDLSP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M6YV86-1", "uniprot_id": "A0A8M6YV86_DANRE", "id": "A0A8M6YV86-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLQPQQPITGNGPSASRGGGLSVHPGMHPLNSIHPAAQHRPDGADPAGLEGTENGHDNRRDIGDILQQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSMRNVQEEEPPDPQLVRLDNMLLAEGVAGPEKGGG-AAAAVSAATSSGG----MSPDSSLEHSDYKSKLSQIRNIYHTELEKYEQACSEFTTHVMNLLREQSRTRPVSPREIERMVAIIHRKFSSIQTQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKQCSITVSQVSNWFGNKRIRYKKNIGKYQEEANLYAMKTALGATQSEDSPHTPNSTGSGSFS-----LSGSADCFLGVPPMNG----EQPPYHMGAQDAQSRFSER-----LYITRESRTNGNWQEQNSPPSAASP----GTDHSVDSD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . * * . .* * . * ::***:******:*::********:**:********************* **:*. ***** ****:******:************ **** :**:* ** ..*.::*****::**:***:*** *********.******************::*:*:**** ***:***:** *******************************:*:***********************::*.*********************** *****:** *.* * : . *.: : * :. : . . :.: . : .* * *. * ", "identical_positions": 236, "similar_positions": 59, "identity": "37.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000405-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NR90-1", "uniprot_id": "DAZ3_HUMAN", "id": "Q9NR90-1", "name": "Deleted in azoospermia protein 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAANPETPNS-----TISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGS--QIHFHGKKLKLGPAIRKQK--LCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT---------GCQLLVYNYQEYPTYPDSAFQ---------------------------------VTTGYQLPVYN-------------------------------------YQPFPAYPRSPFQVTAGYQLP---------------VYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNS------------------------------------------------------------------------PFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q13117-1", "uniprot_id": "DAZ2_HUMAN", "id": "Q13117-1", "name": "Deleted in azoospermia protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAANPETPNS-----TISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGS--QIHFHGKKLKLGPAIRKQK--LCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT---------GCQLLVYNYQEYPTYPDSAFQ---------------------------------VTTGYQLPVYN-------------------------------------YQPFPAYPRSPFQVTAGYQLP---------------VYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86SG3-1", "uniprot_id": "DAZ4_HUMAN", "id": "Q86SG3-1", "name": "Deleted in azoospermia protein 4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAANPETPNS-----TISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGS--QIHFHGKKLKLGPAIRKQK--LCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQS-AANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSS------------------------------------------------------------------------PFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NQZ3-1", "uniprot_id": "DAZ1_HUMAN", "id": "Q9NQZ3-1", "name": "Deleted in azoospermia protein 1", "aln": "MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNS-----TISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGS--QIHFHGKKLKLGPAIRKQK--LCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQS-AANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSS------------------------------------------------------------------------PFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JYV3-1", "uniprot_id": "A0A0G2JYV3_RAT", "id": "A0A0G2JYV3-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MSATTSEAPNS-----AVSREASTQSSSATTSQGYVLPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFYNDVDVQKIVES--QINFHGKKLKLGPAIRKQN--LCTYHVQPRPLIFNPPPPPQFQSVWSSPNAETYMQPPTMMNPITQYVQA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YPPYPSSPVQVITGYQLPVYNYQMPPQWP-------AGEQR---SYVIPPAYT-------------TVNYHCSEVDPGA------------------------------------------------------------------------------------------DLLPN-----------ECSVHDAAPASGNGPQKKSVDRSIQTVVSCLFN--PENRLRNSLVTQDDYFKDKRVHHFRRSRAVLKSDHLC--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64368-1", "uniprot_id": "DAZL_MOUSE", "id": "Q64368-1", "name": "Deleted in azoospermia-like", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MSATTSEAPNS-----AVSREASTQSSSATTSQGYVLPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFYNDVDVQKIVES--QINFHGKKLKLGPAIRKQN--LCTYHVQPRPLIFNPPPPPQFQSVWSSPNAETYMQPPTMMNPITQYVQA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YPPYPSSPVQVITGYQLPVYNYQMPPQWP-------AGEQR---SYVIPPAYT-------------TVNYHCSEVDPGA------------------------------------------------------------------------------------------DILPN-----------ECSVHDAAPASGNGPQKKSVDRSIQTVVSCLFN--PENRLRNSLVTQDDYFKDKRVHHFRRSRAVLKSDHLC--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92904-1", "uniprot_id": "DAZL_HUMAN", "id": "Q92904-1", "name": "Deleted in azoospermia-like", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTANPETPNS-----TISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVES--QINFHGKKLKLGPAIRKQN--LCAYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNPITQYVQA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YPTYPNSPVQVITGYQLPVYNYQMPPQWP-------VGEQR---SYVVPPAYS-------------AVNYHCNEVDPGA------------------------------------------------------------------------------------------EVVPN-----------ECSVHEATPPSGNGPQKKSVDRSIQTVVSCLFN--PENRLRNSVVTQDDYFKDKRVHHFRRSRAMLKSV-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9YGW7-1", "uniprot_id": "DAZL_DANRE", "id": "Q9YGW7-1", "name": "Deleted in azoospermia-like", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MVQGVQLPVCLICGLYSQDIQKHRQGFPSSLKLSNGYILPEGKMTPNTLFVGGIDMKVDENEIREFFAKYGSVKEVKIITYRGGICKGYGFVYFSEDVDIQTIVDQ--PISFKGKKLKLGPAIMKER--SSRSVSSP---MIGP-------SQWVNPTPYMYCS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CCPPGLAPPSPVFSGGNQ----YMQP------------------------------------------YSYSSPPG-------------------------------------------------------------------------------------------------------------------IMVPQVPMNYAQTTYAYQYPLPQWCGEQ-------RTRLVNQN----------FVDCGVQTLLTLM---------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24207-1", "uniprot_id": "BOULE_DROME", "id": "Q24207-1", "name": "Protein boule", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MHKIAAAPPPS-------ATPGGGLETPLAAPK-----YGTLIPNRIFVGGISGDTTEADLTRVFSAYGTVKSTKIIVDRAGVSKGYGFVTFETEQEAQRLQADGECVVLRDRKLNIAPAIKKQPNPLQSIVATNGAVYYTTTPPAPISNIPMDQFAAAVYPPAAGVP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AIYPPSAMQYQPFYQYYSVPMNVPTIWP--------------------------------------QNYQENHS-------------------------------------------------------------------------------------------------------------------PLLHSPTSNPHSPHSQSHPQSPCWSIED------LRDTLPRV---------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :. .: *.: ** :*****. * :: *. **:**..***. * *:.****** * : : * : . : ::.:**::.*** *: . . . . .. . : .* . . : ", "identical_positions": 34, "similar_positions": 44, "identity": "4.12%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000406-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RDK4-1", "uniprot_id": "M0RDK4_RAT", "id": "M0RDK4-1", "name": "Membrane-associated phosphatidylinositol transfer protein 3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKAGSAG---------GPSPG---GGAPWHLRNVLSDSVESSDDEFFDAREEVAEGKNAILIGMSQWSSND----LVEQIETMGKLDEHQGEGATACTSSILQEKQRELYRVSLRRQKFPAQGSIEIHEDVEEGCSQRSCKTHVLLLVLHGGNVLDTGSGDPSCKAADIHTFSSVLEKVTRAHFPAALGHILIKFVPCPAICSEAFSLVSNLNPYSHDEGCLSTSQD---HVPLAALPLLAISSPQYQDAVATVIERANHIYGEFLKSSDGIGFNGQVCLIGDCVGGLLAFDAICYSAGPSGDSPGSSSRKGSISSTQDTP-VVVEEDCNLASSKRLSKSNIDVSSGVEDED-PKRPLTRKQSDSSTYDCEAITQHHAFLSSIHSSVLKDEAEAPAAGTPQLSEVSLGRFDFDVSDFFLFGSPLGLVLAMRRTVLPGIDGFQMRPACSQVYSFFHCADPSASRLEPLLEPKFHLVPPVSVPRYQRFPLGDGQSLLLADALHTHSPLFLEGSSRGSPPLLDAPASPPQAPRSQRPERRLSEGSSHSDSSESSDSLAPMGASRITAKWWGTKRIDYALYCPDVLTAFPTVALPHLFHASYWESTDVVAFILRQVMRYESAS-VKESTGLDPTALSPANPREKWLRKRTQVKLRNVTANHRANDVIAAEDGPQVLVGRFMYGPLDMVALTGEKVDILVMTEPSSGRWVHLDTEITNNSGRITYNVPRPRRLGVGVYPVKMVVRGDQTCAMSYLTVLPRGMECVVFSIDGSFAASVSIMGSDPKVRPGAVDVVRHWQDLGYMILYITGRPDMQKQRVVSWLSQHNFPQGMIFFSDGLVHDPLRQKAIFLRNLMQECFIKITAAYGSTKDISVYSVLGLPASQIFIVGRPTKKYQTQCQFLSEGYAAHLAALEASHRSRPKKNNSRMILRKGSFGLHAQPEFLR--------KRN-HLRRTMSVQQPDPP---ATNPKPERAQSQPESDKDHERPLPALS----WARGAPKFESVP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UHE1-1", "uniprot_id": "PITM3_MOUSE", "id": "Q3UHE1-1", "name": "Membrane-associated phosphatidylinositol transfer protein 3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKAGSAG---------GPSPG---GGAPWHLRNVLSDSVESSDDEFFDAREEVAEGKNAILIGMSQWSSND----LVEQIETIGKLDERQGDGATACTSSILQEKQRELYRVSLRRQRFPAQGSIEIHEDGEEGCSQRSCKTHVLLLVLHGGNVLDTGSGDPSCKAADIHTFSSVLEKVMRAHFPAALGHILIKFVPCPAICSEAFSLVSNLNPYSHDEGCLGTSQD---HVPLAALPLLAISSPQYQDAVATVIERANHIYGEFLKSSDGIGFNGQVCLIGDCVGGLLAFDAICYSAGPSGDSPGSSSRKGSISSTQDTP-VVVEEDCSLASSKRLSKSNVDVSSGVEDED-PKRPLPRKQSDSSTYDCEAITQHHAFLSSIHSSVLKDEAEAPAAGTPQLSEVSLGRFDFDVSDFFLFGSPLGLVLAMRRTVLPGIDGFQMRPACSQVYSFFHCADPSASRLEPLLEPKFHLVPPVSVPRYQRFPLGDGQSLLLADALHTHSPLFLEGSSRGSPPLLDAPASPPQAPRFQRTERRLSKGSSHSDSSESSDSLAPMGASRITAKWWGTKRIDYALYCPDVLTAFPTVALPHLFHASYWESTDVVAFILRQVMRYESAS-VKESTGLDPTALSPANPREKWLRKRTQVKLRNVTANHRANDVIAAEDGPQVLVGRFMYGPLDMVALTGEKVDILVMTEPSSGRWVHLDTEITNNSGRITYNVPRPRRLGVGVYPVKMVVRGDQTCAMSYLTVLPRGMECVVFSIDGSFAASVSIMGSDPKVRPGAVDVVRHWQDLGYMILYITGRPDMQKQRVVSWLSQHNFPQGMIFFSDGLVHDPLRQKAIFLRNLMQECFIKITAAYGSTKDISVYSVLGLPASQIFIVGRSTKKYQTQCQFLSEGYAAHLAALEASHRSRPKKNNSRMILRKGSFGLHAQPEFLR--------KRN-HLRRTMSVQQPDPP---AANPKPERAQSQPESDKDHERPLPALS----WARGPPKFESVP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZ71-1", "uniprot_id": "PITM3_HUMAN", "id": "Q9BZ71-1", "name": "Membrane-associated phosphatidylinositol transfer protein 3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKAGRAG---------GPPPG---GGAPWHLRNVLSDSVESSDDEFFDAREEMAEGKNAILIGMSQWNSND----LVEQIETMGKLDEHQGEGTAPCTSSILQEKQRELYRVSLRRQRFPAQGSIEIHEDSEEGCPQRSCKTHVLLLVLHGGNILDTGAGDPSCKAADIHTFSSVLEKVTRAHFPAALGHILIKFVPCPAICSEAFSLVSHLNPYSHDEGCLSSSQD---HVPLAALPLLAISSPQYQDAVATVIERANQVYREFLKSSDGIGFSGQVCLIGDCVGGLLAFDAICYSAGPSGDSPASSSRKGSISSTQDTP-VAVEEDCSLASSKRLSKSNIDISSGLEDEE-PKRPLPRKQSDSSTYDCEAITQHHAFLSSIHSSVLKDESETPAAGGPQLPEVSLGRFDFDVSDFFLFGSPLGLVLAMRRTVLPGLDGFQVRPACSQVYSFFHCADPSASRLEPLLEPKFHLVPPVSVPRYQRFPLGDGQSLLLADALHTHSPLFLEGSSRDSPPLLDAPASPPQASRFQRPGRRMSEGSSHSESSESSDSMAPVGASRITAKWWGSKRIDYALYCPDVLTAFPTVALPHLFHASYWESTDVVAFILRQVMRYESVN-IKESARLDPAALSPANPREKWLRKRTQVKLRNVTANHRANDVIAAEDGPQVLVGRFMYGPLDMVALTGEKVDILVMAEPSSGRWVHLDTEITNSSGRITYNVPRPRRLGVGVYPVKMVVRGDQTCAMSYLTVLPRGMECVVFSIDGSFAASVSIMGSDPKVRPGAVDVVRHWQDLGYMILYITGRPDMQKQRVVSWLSQHNFPQGMIFFSDGLVHDPLRQKAIFLRNLMQECFIKISAAYGSTKDISVYSVLGLPASQIFIVGRPTKKYQTQCQFLSEGYAAHLAALEASHRSRPKKNNSRMILRKGSFGLHAQPEFLR--------KRN-HLRRTMSVQQPDPP---AANPKPERAQSQPESDKDHERPLPALS----WARGPPKFESVP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P8F6-1", "uniprot_id": "A0A8M1P8F6_DANRE", "id": "A0A8M1P8F6-1", "name": "Membrane-associated phosphatidylinositol transfer protein 3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDRMTQE---------TRVPSRKHSASHWRLQNIAQESVESSDEEFFDAR-DVMEGKTALLLEMSQWNSND----LVEQIETLGHLEHS----------------RESLYR--LRHPRCAPQSSVDGLEDME-----RKCRTQLLILVIHGGHILDSGGGDPGGKAGDAATLASVLERVARAHFQAAADSMLVRLVPCPPVCADAFTLVSNLNPYSYDENCVSTSVD---HLPLAALPILAIAAPHYQNAVAAVIAQANQVYRNFLQSPEGVGFTGQVCLVADCVGGVLCFDALCFSGDKQHRSPEGGSTNNSTESLKEKPGVVNSLSPTLRGSKRLSKSNIDVSTPCDVLSGIRHPLIRKQSDSCDADVASG-QREVFISSLSQ---DDQCGSRQALSP-------GCFEFEVSDCFLLGCPLGLVLAMRRTVVPGVDVAQLRPACSQIFNLFYPSDPSASRLEPLLHSVLTQLPPFPVPRYQRCPLGDGRSTLIVDTVLRHVTEGGVSADGAADQCYGGSVSR------RGSDRAVPLGSEGTAPSE------PVSISQVCSRWWGSKRLDYVLYCPDVLTTFPTIALPHLFHASYWESTDAVAFILRQVMRCDCLK-AGEADCSDAIPISPSSPREKWLRRRTHVKLRNITANHRVHDVIVTEDGPQTLVGRFMYGPLDMVTLTGEKVDVFLKTQSGSGRWVLFDTVVTSSSGRVSYTIPDNKRLGVGVYPIKMVVKGDQTSAEAFLTVLPQGMECVVFSIDGSFAASVSLMGSDPKVRPGAVDVVRHWQDLGYLIIYITGRPDMQKQRVVSWLSQHNFPQGMVFFSEGLVHDPLRQKTIFLKSLVKECHIKISAAYGSMKDMSVYSTLGLAPNQIYIVGRPSKKHQHQCQFLSEGYAAHLSTLEFEHGSRSKKN--RMVLRQGSFGLSSKTDFLSPSPDFLSCKRTPLLRRAMSVQQPSPPSSSVSTPKPERAQSQPESHKDGPEIRIQYDDQDEEEEEEGRIQDVVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43125-1", "uniprot_id": "RDGB_DROME", "id": "P43125-1", "name": "Protein retinal degeneration B", "aln": "MLIKEYRIPLPLTVEEYRIAQLYMIAKKSREESHGEGSGVEIIINEPYKDGPGGNGQYTKKIYHVGNHLPGWIKSLLPKSALTVEEEAWNAYPYTRTRYTCPFVEKFSLDIETYYYPDNGYQDNVFQLSGSDLRNRIVDVIDIVKDQLWGGDYVKEEDPKHFVSDKTGRGPLAEDWLEEYWREVKGKKQPTPRNMSLMTAYKICRVEFRYWGMQTKLEKFIHDVALRKMMLRAHRQAWAWQDEWFGLTIEDIRELERQTQLALAKKMGGGEECSDDSVSEPYVSTAATAASTTGSERKKSAPAVPPIVTQQPPSAEASSDEEGEEEEDDDEDENDAIGTGVDLSANQGGSAQRSRSQSIQMAQKGKFGSKGALHSPVGSAHSFDLQVANWRMERLEVDSKSNSDEEFFDCLDTNETNSLAKWSSLELLGEGDDSPPPHGGPSSAASVGGRGNSRQEDSIFNQDFLMRVASERGNKRQLRSSASVDRSHDSSPPGSPSTPSCPTTILILVVHAGSVLDAAS-ELTAKKSDVTTFRGSFEAVMRQHYPSLLTHVTIKMVPCPSICTDALGILSSLSPYSFDASPSAADIPNIADVPIGAIPLLSVASPEFHETVNKTVAAANIVYHEFLKSEEGHGFSGQIVMLGDSMGSLLAYEALCRSNGSQPGTASGASNSGGDAAT-----NINTHNPLSPRNSRLDDDERFIEADLDAKRLLVAPSPRRRRSSSSSDSRAT-----------------------------------KLDFEVCDFFMFGSPLSVVLAARK--LHDAKAALPRPNCHQVYNLFHPTDPIASRLEPLLSARFSILAPVNVPRYAKYPLGNGQPLHLLEVIQSHPQHFNDGNN-----LLAG--------------RRLSDASMQSTISGLIENVSLSTIHALQNKWWGTKRLDYALYCPEGLSNFPAHALPHLFHASYWESPDVIAFILRQIGKFEGIPFVGSNDDKDNASFHPGQPREKWIKKRTSVKLKNVAANHRANDVIVQEGREQRLNARFMYGPLDMITLHGEKVDVHIMKDPPAGEWTFLSTEVTDKNGRISYSIPDQVSLGYGIYPVKMVVRGDHTSVDCYMAVVPPLTECVVFSIDGSFTASMSVTGRDPKVRAGAVDVCRHWQELGYLLIYITGRPDMQQQRVVSWLSQHNFPHGLISFADGLSTDPLGHKTAYLNNLVQNHGISITAAYGSSKDISVYTNVGMRTDQIFIVGKVGKKLQSNATVLSDGYAAHLAGLQAVGGSRPAKGNARMVIPRGCFNLPGQTANPR--------RRRYLERKTVSS----------------CCLMVFQTT----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:. . : *::..: :* ..**:****. .. * :. ...* .: . : : * *: : ... . . .. .* * :*:**:*.* :**:.. : * .* *: . :* * * *: : : :::****.:*::*: ::* *.***.* . .:. .:*:.*:*:*::::*.::::* .: ** :* :**:* :* **.**: ::.*.:*.:*.::*:* * . . :. ..* ... : . ..**...: :.: : * *:: .*. * : ::*:*.* *::*.**.:*** *: : . . ** * *::.:*: :** ******** . : :.*. **** : ***:*:. : :.: * . . . * :. .* : * : :***:**:**.****: *: **: *************.*.:******: : : . * .: *..*****:::** ***:*::****.:***. *. * * .*********::* *****: : :. :*.*. :.* :*...**::*.:* ** *:**:****:**:*.. .:::*:* ***********:**:*: * *****.***** ****:***:::*********:*************:*:: *::** *** :*: :*..*::: *.*:***** **:***: :*: ..**:***: ** * :. .**:******: *: **. *. **:: :*.*.* .:. :* *:::* . :: ", "identical_positions": 309, "similar_positions": 282, "identity": "22.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000411-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXQ5-1", "uniprot_id": "WNT4_RAT", "id": "Q9QXQ5-1", "name": "Protein Wnt-4", "aln": "MSPRSCL----RSLRLLVFAVFSAAASNWLYLAKLSSVGSISEEETCEKLKGLIQRQVQMCKRNLEVMDSVRHGAQLAIEECQYQFRNRRWNCSTLDS-LPVFGKVVTQGTREAAFVYAISSAGVAFAVTRACSSGDLEKCGCDRTVHGVSPQGFQWSGCSDNIAYGVAFSQSFVDVRERSKGASSSRALMNLHNNEAGRKAILTHMRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALKEKFDGATEVEPRRVGSSRALVPRNAQFKPHTDEDLVYLEPSPDFCEQDMRSGVLGTRGRTCNKTS-KAIDGCELLCCGRGFHTAHVELAERCGCRFHWCCFVKCRQCQRLVEMHTCR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22724-1", "uniprot_id": "WNT4_MOUSE", "id": "P22724-1", "name": "Protein Wnt-4", "aln": "MSPRSCL----RSLRLLVFAVFSAAASNWLYLAKLSSVGSISEEETCEKLKGLIQRQVQMCKRNLEVMDSVRRGAQLAIEECQYQFRNRRWNCSTLDS-LPVFGKVVTQGTREAAFVYAISSAGVAFAVTRACSSGELEKCGCDRTVHGVSPQGFQWSGCSDNIAYGVAFSQSFVDVRERSKGASSSRALMNLHNNEAGRKAILTHMRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALKEKFDGATEVEPRRVGSSRALVPRNAQFKPHTDEDLVYLEPSPDFCEQDIRSGVLGTRGRTCNKTS-KAIDGCELLCCGRGFHTAQVELAERCGCRFHWCCFVKCRQCQRLVEMHTCR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56705-1", "uniprot_id": "WNT4_HUMAN", "id": "P56705-1", "name": "Protein Wnt-4", "aln": "MSPRSCL----RSLRLLVFAVFSAAASNWLYLAKLSSVGSISEEETCEKLKGLIQRQVQMCKRNLEVMDSVRRGAQLAIEECQYQFRNRRWNCSTLDS-LPVFGKVVTQGTREAAFVYAISSAGVAFAVTRACSSGELEKCGCDRTVHGVSPQGFQWSGCSDNIAYGVAFSQSFVDVRERSKGASSSRALMNLHNNEAGRKAILTHMRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALKEKFDGATEVEPRRVGSSRALVPRNAQFKPHTDEDLVYLEPSPDFCEQDMRSGVLGTRGRTCNKTS-KAIDGCELLCCGRGFHTAQVELAERCSCKFHWCCFVKCRQCQRLVELHTCR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P855-1", "uniprot_id": "A0A8M1P855_DANRE", "id": "A0A8M1P855-1", "name": "Protein Wnt", "aln": "MPTVSSVTLTGRLLLLLLWAAHLAMATNWLSLARLSRSRPVSGAEPCGRLRGLSPGQVGVCRARGEVMESVRKASEMVIEECQHQFRNRRWNCSTTPRGINVFGRVMNQGTREAAFVHALSSAAVAVAVTRGCSRGELERCGCDRKVRGVSPEGFQWSGCSDNLSYGVAFSQTFVDEPERAKGMSSGRPLMNIHNNEAGRKAILHNMQVECKCHGVSGSCELRTCWKVMPPFRRVGAVLKERFDGATEVRLTRVGSRTALLPRDPQVKPPATRDLVYLAPSPDFCRLDPDNGIPGTAGRRCNGTSRLAPDGCELLCCGPGFRAGRAEVVQRCSCKFSWCCSVRCQQCKNTVLIHTCRE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. *.: * * **::*.. * *:*** **:** .:* *.* :*:** ** :*: . ***:***:.:::.*****:*********** : ***:*:.*********:*:***.**.****.** *:**:*****.*:****:**********::*******:*** **:** **.*.***:*********** :*:*************::***:.:****:** .***:*******. **** **:**:.*.** : .***** ******. * .*: ** ** ** ** * ********* **::.:.*:.:**.*:* *** *:*:**:. * :**** ", "identical_positions": 220, "similar_positions": 82, "identity": "61.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000412-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23363-1", "uniprot_id": "BDNF_RAT", "id": "P23363-1", "name": "Neurotrophic factor BDNF precursor form", "aln": "---------------------------------------------------------MTILFLTMVISYFGCMKAAPMKEAN-VHG----QGNLAYPAVRTHGTLESVNGPRAGSRGLTTTSLADTFEHVIEELLDED----QKVRP------------NEENHKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21237-1", "uniprot_id": "BDNF_MOUSE", "id": "P21237-1", "name": "Neurotrophic factor BDNF precursor form", "aln": "---------------------------------------------------------MTILFLTMVISYFGCMKAAPMKEVN-VHG----QGNLAYPGVRTHGTLESVNGPRAGSRGLTTTSLADTFEHVIEELLDED----QKVRP------------NEENHKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23560-1", "uniprot_id": "BDNF_HUMAN", "id": "P23560-1", "name": "Neurotrophic factor BDNF precursor form", "aln": "---------------------------------------------------------MTILFLTMVISYFGCMKAAPMKEAN-IRG----QGGLAYPGVRTHGTLESVNGPKAGSRGLT--SLADTFEHVIEELLDED----QKVRP------------NEENNKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G051-1", "uniprot_id": "A0AC58G051_DANRE", "id": "A0AC58G051-1", "name": "Brain-derived neurotrophic factor", "aln": "MLPASSATQTNIKNSWSRERICGSGAFSEIRPSQMGPPVQHYIAAQHSIEFQQVRRVMTILFVTMVISYFSCMRAAPMREIPGVQGGHRAEGYLGAAAAAAAAVTSGSRGHGTPQSGGGLPSLTDTFEQVIEELLEVEGEATQQLGPGADQGQGGGGPIDAADSKDVDLYASRVMISNQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSISQWVTAVDKKTAIDMSGQTVTVLEKVPVTNGQLKQYFYETKCNPLGYTKEGCRGIDKRHYNSQCRTTQSYVRALTMDSKRKIGWRFIRIDTSCVCTLTIKRGR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****:*******.**:****:* ::* :* *. ... : .. .. .* : . * **:****:******: : *:: * : : **.***:****:*.***********************************************:****.*****:**** **********::**************:**************:*******************::**********************", "identical_positions": 187, "similar_positions": 40, "identity": "57.19%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000426-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P02751-15", "uniprot_id": "FINC_HUMAN", "id": "P02751-15", "name": "Fibronectin", "aln": "MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMIWDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP--FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQET-AVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRIGDQWDKQHD-MGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHMLNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGD---EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDTTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSS--TELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPG--EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP---PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA---IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVT--LPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHPVG-TDEEPLQFRVPGTSTSATLTGLTRGATYNVIVEALKDQQRHKVREEVVTVGNSVN-EGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTN--TNVNCPIECFMPLDVQADREDSRE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S602-1", "uniprot_id": "B0S602_DANRE", "id": "B0S602-1", "name": "Fibronectin", "aln": "MFGGPLGTALAVALLACAVQCMPKGTGKHKRQAQEHS------VSSVSQDGCVMDGQFYGAGEKWERIYLGSTLLCTCHGVSK-IECKSKPDAEETCYDKVNSRSYRVGETYERPKDGMIWDCTCIGSARGKISCTIANRCHEGGHSYKIGDTWQRPHDTGDYMLECVCLGNGKGEWTCKPVAERCYDNTAGTSYMVGETWEKPYQGWMIVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKTDSRGHVLQCLCTGNGRGEWKCERHASLHTTSLGTGSRVVTNVQPAVYHPQGVPEHPVEGSCLTEAGVSYAPGMRWSKAQGSKQMLCTCLGNGVSCEESESQSQVYGGTSGGEPCAFPFVFMGKTFYSCTSEGRNDGQLWCSTSSDFEKDYKYSFCTSNNVVVTTRGGNSNGALCQFPFLYNGRNYTDCTADGRRDGMKWCGTTYNFDKEQRFGFCPMAAHEEVCTTNEGVMYRVGDQWDRRHDVLGHMMRCTCVGNGRGEWSCIAYSQLKDQCIVDNLTYEVNQTFTKRHDEGYTMNCTCFGQGRGRWKCDAIDQCQEPETRVFYQIGESWDKLIQGIHYRCYCYGNGIGELSCEPQHSISGGHRPVQVIISEAGNQPNSHPIQWNAPASAHITQYILKWRPKNTHIQWMEVTIPGHVNSYTIAGLKPGVTYEGQLISILRFGRRETTRFDFSTVHGSLETSE----GETTQPPRMVDTSESVTEITSSSFVISWVSASDTVSGFRVEYELSEEGGQTGQPMILDLPHSATSVNISELLPGRKYTVNVYEVTGEGEPNLILTTSQTTAPDAPSDHEVEDVADTSIRISWSKPLAPITGYRVVYTPSEEGSSGSVELNLPEHSTSLTLGDLRPGVLYNISIFSVEENQESEPVFVQVTTAGEPLAEEVPSPTDLQFYEVSDSKITITWTSPSSEVSGYRVSVGEVGPDGLIEKEVPYPVTQNAYAEITHLQPGTLYRFFIFSLKSGEESEPLVGEQATKPDPPTDIYFSNITEDSAVIVWLPPTAQITGYRLFLTVEG-SNPKQLRIPGRLSQYTLLNLQPDTEYSATLHAERGNVLSEGSIATFATTPPMGNAPYFSTDVTDTSIIVSWSPLPKIGYKLTVRPSQGGEAPRDVTSELGSVLISGLTPGVEYTYSVQPVISGQEHGNPITRRVVTPLSPPTDLNLESNPNTGKLTVQWNDANIPDITGYRVTCTPTKGQQGNSLEEFVKAGQNSCTLENLSPGVEYNVSVFTVKDDMESVPVFTTVTPDVPKITDLSFINVTDSTIGLSWSPLNSTAVTGYRITVLAAGDSVPIFVEFVEPTTGFYTVHGLEPGIDYDITVTTVTENGESEPITITQQTAVPAPYGLSFGEVTADTMLVTWKAPQVPKSSDINQYIIRYHPVDEDDETTERTVEGSENFVVLRHLVPNTEYLVSVICVYEGREGSPAIGTQRTVFDAPVGLQFSDVGTTSFTVRWQAPRAIISGYRIRYQMTSG-GRAKEERLPPSRSHFTLTGLTPETEYSISVYAVSGSRDSLPLTGTQSTISDAPTDLEVISSTPTSITVRWDAPSVTVRYYRITHGESGGSDAPLEFMVPGSQSTATIEDLRPGTDYTITVYAVTGRGDSPASSTPIHVKHRTDIDSPSQMEVTDVKDNTITVRWTPAAGPISRYRVNATPLTGEGPVLHAETTSDHTEITFSGLMPAVEYSIKVYALGQDGESLPLVENVVTTVDKPKDLSFTDVESSSMRISWDSPDGVVSSYRVLYYSPEEGERELFPAPHGDDESAVLHGLRPGTEYTVKVIALHDQSPSTALVGTQTTGIPGPTRLQFSQVGPTSFTVSWSSSDASLTGYRVAVSPKSKSGPTKEENITPDSTEFHATGLMPGTDYEVEVYGVKNSLTSPRVKGEITTPDNISPPRRVRISNVKDSSITLTWRSKTEAISGFLVEATPTMGGHNPIQRTIEPDSRTYTIAGLEPGTNYKINIYTLNGNSRSEPFTLTATTAKPVISPPTNLHFTSLASTSISFTWEPPRSTITGYYVTYEEAGGIPKELTPRPQAARTFASISGLIPGTEYIIKIVALNGAQRSTPLIGKARTQLEIEQLPPQLPNPSRPHLEVLDVPE--DNDNFNNHVHVLGPNRHNTLGQQGQHIYTEYQSFNLGNNGQQPHHPNHGEPLVYIPLPGAD--GQRVPVVKVN--EGQEAGFPFG-GLFNETNLPQESQTQTTIVWQPVPHTSEYVVWCDPITEINEKSFQMRLPGTSTSATLIGLTSGASYNVLVESVNGDQKQKVLQDVVTVGNSVPGAGVIPTGRDVCYDSFTATYHEVNTEWERMSETGFKLWCKCLGLGSGHFRCDSSKWCHDSGHNYRIGEKWDRRAENGHMMSCTCLGNGKGEFKCEPHESTCYDEGKLYQVGNQWQKEYLGAICTCTCYGGQQGWRCENCRRPGAEVDADLIQPPVRTDAFDRYRENALRKLNIQCPIECLRP-DLLADAHSPHD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ** * :*: . .. ..*:.* *****: . * *: ** :*:.* .::*** ***.:*:***:* *: ::*:***:*****:** ...:****:*******.*********:.**:*************:********:***:**.*******************:**:*:*::*****:*************:**************************************.*.**::***:**************:*::*** *:*. .*:*:.***:** *: * * *:*::** *: **:* *:**.**************:*: : :*.***.*.****.:**.: *:******:***:**:*****:*::*:* ******.:.*:* ***********:******.:******::****.******* *:* :*:***********:**********:*****::** :****************:*******:******::**:**:** ***:**: :***************.:****:.** .*****:**:* ::*::*:*****.**** *:* :: ... **:*:*:*: .************ .:**::***:*****: :* *.*****:***** ******.******** ::*::*.*****:*. * .:. **** . :* *********:****:**********************. :* **** :******.:******* ****::: :** .***:**********.* *::* **** : **:* *******:**:** **** .****** :.*:**.**:*** ***:*::******* **.:* *:* * :: **** **** **:* *:** **.*.* *:****.* *. * *: *:::*::**:* *.**. * * :*::. *.**:**..:*:** *.**:: * * *:.:.:: * ** ******** : : .:*:* .: :*:*.* **** :**:.:* * :** * : ..*:* * .. * :.*:**:*:*:::*:* *:**:** ***********:***: **:::*********.*::* : .***:. **..:*********:*:**:**:** ***.*: :. *******:* ***:*********.*:*.*.***::*****:******:***** ****: *: *:**::*****:::***:*** *:****::: ******:***:.:*** :**:.:.*:*** **********:* *: :.*** * *:*******.* .* * :: .*** *** . * * *:.::::** **.::::.:* ::. *:* *** :*:*.***:*** .*** :*.:* * *:* :*:*.*::***: :.****:* **** *:*****:: **.:*:*:* **. :***.*** *** :*: *:.* .:* * * ***:**.* ****:::****: : ****:*********:**:**... ** ****:*****..*:**.*******************.** :::**:**.****:****:**:*:*:* *::.*:: ***.:** .* **. : .*:**:*:.** *:*** :.*** . .*** ***:..**.:*:**.*:****: .*::*:*:**:* ** *** * ***:* :******.*::::* *:*****:****.*:****: * .*:***:*.**.** *:*:** ***::..*:..:..****** *:**.*:** ** *::***:.. .:*** .*.***.**.:*::*** .:* :** :*:*****.*:::..:::**::**:***:*:** *:*.*: * :.******:** *:***:**:***:*** :****.*:**.*..: *:** *..*:**:* : :..*: .:*:***: **** :.**:.*. *:*:.***:.. * *:*:** ***** * ::**:. *:* ****: :*: : :. **:*. *:****. :: * .* * : * .**: . * : :. ::. *. . *: : * * . *:.: : :: : : :*.* ** ::. **: :**** * *. .****:: *.*: :*:.:*:*:********* *** **:***:**:::.:*::** ::******** *: . * *:*.:*.::: *. *******:**** *:***:**********:****.* **:*******:.***:****************:***:****:** *:**:***********:***:***:****:******.* ..: .: :**::.: *::*****: * *: ** ...::", "identical_positions": 1441, "similar_positions": 675, "identity": "57.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000427-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A6M3Q9I2-1", "uniprot_id": "A0A6M3Q9I2_DROME", "id": "A0A6M3Q9I2-1", "name": "", "aln": "--MHSPAAKVSGYVVLMIVQIIFLVLFWLFVRYEKTALPLAIDAEDAGSANEHVSKYPQFQDIQVMIFIGFGFLMTFLRKYGYSATGFTLFMAALVVQWAVLMKGFLHME-GGKISLSLENIIDADIAAAVPLISMGALLGRTTPIQLLCMSVFEVALFAANEYLALHVFSICDCGGSITVHAFGAYFGLAVALMLRPASDQNETGKLEGASYTSDIFAMIGTTFLWVYWPSFNSVLAD-GAGGERAILNTFLSLAAATVTTFVVSALVSHENKLDMVHVQNSTLAGGVAVGTVCNLLLGAHGAVLIGIIAGTVSVLGYRYLTPWMTANLRLHDTCGVHNLHGMPALISAIASAIYASMATVGEYQSELQDIFPAMVGTNG---------TETKIMGGLGRNATSQAGYQLFGIAVTLLIAIGGGILTGAVLKYTNFRNLKKDEHHQDEHYWEVPAAENKEEYLNMLAKLLDDDAAATNSNSQSAANFNWRPFLLRNWNAIVPANNLYVRGALH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B0UYU0-1", "uniprot_id": "B0UYU0_DANRE", "id": "B0UYU0-1", "name": "", "aln": "MKKNSTNLRLRLPALIFASEVVIVVLYACFVTYDDHANALLQNNQTRHMENSFYQNYPFFADIQVMIFIGFGCLLAFFRRYGFGGMVFNFLVATFTIQWAILIQGFFQFFYDGKIHLSVLNLINAEFACAVVLISFGAVLGKTSPVQLLIMALLEIPLFGVTEWAVLKYLRINDAGGSILIHIFACYFGLGVTFVLYRPS-LNEGHPKVSTSYQSDLLSVMGTLFLWVFWPSFNSALTFKGDDQHRAVLHTFIGLSASTITAFALSSMLSKNGKISMADVQNVTLAGGVTVGASVDMMISPAAAYVLGVMGCFACMLGYKYLSPVLAQKLRIQDQCGIHNLHGLTGLISSLAGICAILLATEETYGPSLYETFSHQAPPEGDPQLMELQQLIPDLEAGLGRSAKEQALFQVAALFGTIAVSAVGGMLTGVVLKLPFLASPSDEQCFDDEVFFTVPS---------------DYDCVNVLSETRKAENE--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. :: .::: :::::**: ** *:. * .* : : *.. .:** * *********** *::*:*:**:.. *.:::*::.:***:*::**::: .*** **: *:*:*::*.** ***:**:**:*:*:*** *:::*:.**...*: .*: : * *.**** :* *..****.*:::* .* ** .:** **:::::** ****:******.*: * . .**:*:**:.*:*:*:*:*.:*:::*::.*:.*..*** ******:**: ::::.. .* ::*::. ..:***:**:* :: :**::* **:*****:..***::*. :** * ..* : *. . .:* ..: .****.*..** :*: .: *: :: **:***.*** . : . ..:: .:** :: **: * *.. . *:::.* * ", "identical_positions": 179, "similar_positions": 183, "identity": "34.82%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000427-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49654-1", "uniprot_id": "P2RX3_RAT", "id": "P49654-1", "name": "P2X purinoceptor 3", "aln": "-----MNCISDFFTYETTKSVVVKSWTIGIINRAVQLLIISYFVGWVFLHEKAYQVRDTAIESSVVTKVKGFGRYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPENEEKYRCVSDSQCGPER--FPGGGILTGRCVN---YSSVLRTCEIQGWCPTEVDTVEMPIMMEAENFTIFIKNSIRFPLFNFEKGNLLPNLTDKDIKRCRFHPEKAPFCPILRVGDVVKFAGQDFAKLARTGGVLGIKIGWVCDLDKAWDQCIPKYSFTRLDGVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKAFGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADHYKARKFEEVTETTLKGTASTNPVFASDQA---TVEKQSTDSGAYSIGH---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UR32-1", "uniprot_id": "P2RX3_MOUSE", "id": "Q3UR32-1", "name": "P2X purinoceptor 3", "aln": "-----MNCISDFFTYETTKSVVVKSWTIGIINRAVQLLIISYFVGWVFLHEKAYQVRDTAIESSVVTKVKGFGRYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPENEEKYRCVSDSQCGPER--FPGGGILTGRCVN---YSSVRRTCEIQGWCPTEVDTVEMPIMMEAENFTIFIKNSIRFPLFNFEKGNLLPNLTDKDIKKCRFHPEKAPFCPILRVGDVVKFAGQDFAKLARTGGVLGIKIGWVCDLDKAWDQCIPKYSFTRLDGVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKAFGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADHYKARKFEEVTETTLKGTASTNPVFTSDQA---TVEKQSTDSGAYSIGH---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56373-1", "uniprot_id": "P2RX3_HUMAN", "id": "P56373-1", "name": "P2X purinoceptor 3", "aln": "-----MNCISDFFTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIESSVVTKVKGSGLYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPESEEKYRCVSDSQCGPER--LPGGGILTGRCVN---YSSVLRTCEIQGWCPTEVDTVETPIMMEAENFTIFIKNSIRFPLFNFEKGNLLPNLTARDMKTCRFHPDKDPFCPILRVGDVVKFAGQDFAKLARTGGVLGIKIGWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKAFGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADQYKAKKFEEVNETTLKIAALTNPVYPSDQT---TAEKQSTDSGAFSIGH---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58H6R0-1", "uniprot_id": "A0AC58H6R0_DANRE", "id": "A0AC58H6R0-1", "name": "P2X purinoceptor", "aln": "MAPRVLGFIKGFFVYETAKSVVVKSWSVGIINRIVQLLIILYFICWVFMHEKAHQLRDTGIESAVMTKVKGLGNFNDRVMDVADYVIPSQGASSFSIITNMVVTANQTQGYCPEIEKKFSCTSDGDCEKKIGLNIGNGMITGKCLNDNGTSNDTWRCEIQGWCPAEDDTISGKPMHEVENFTIFIKNSIRFPLFGVARGNFPSSLNRSYIQSCNYDPVRHPFCPIFKVGDILKHLNQSLENITKIGGEIGININWKCNLDYDEENCNPKYFFTRLDAAFEHSSVSKGYNFRFAKYYQSEDGTEYRTLHKAYAIRFEIIVSGNAGKFNVVPFLINLVAAFTSVGLATVFCDIILLNFHKGADEYKAKKFEEVSGVVPE--SGSNILYKGSQVSIKALEKNSNDSGTFSIGRQEM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. *..**.***:********::***** ****** **: ***:****:*:***.***:*:***** * : :*****:*** *.**:* * ***:*:** ** **:*** *:*: *.**.:* : *.*::**:*:* *. ********:* **:. * *.****************.. :**: ..*. :: *.:.* : *****::***::*. .*.: :::: ** :**:*.* *:** ::* *** *****.. *:**** **********: *:*:***** **:.***:::* *******::* :*. ********:.**:******** ****.***:*****. .. : : :* :: ..*. : **:*.***::***: ", "identical_positions": 227, "similar_positions": 107, "identity": "54.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000427-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KAH3-1", "uniprot_id": "A0A0G2KAH3_RAT", "id": "A0A0G2KAH3-1", "name": "T-box transcription factor TBX20", "aln": "---------------------------------------------------------------MEFTASPKPQLSSRANAFSIAALMSSG--GPKEKEAAENTIKPLEQF---------------VEKSSCAQP-----------------------------------------------------------LGELTSLDAHAEFGGGGGSSPSSSS--------------------------------LCTEP--LIPTTPIIP----SEEMAKIACSLETKELWDKFHELGTEMIITKSGRRMFPTIRVSFSG----VDPEAKYIVLMDIVPVDNKRYRYAYHRSSWLVAGKADPPLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELDQHGHIILNSMHKYQPRVHIIKK---KDHTASLLNLKSEEFRTFIFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDIERESVESLIQKHSYARSPIRTYG--------------EEDVLGEESQTTPNRGSAFTTSDNLSLSSWVSSSSSFP-----------------GFQHPQPLTALGTSTASIATPIPHPIQGS----LPPYSRLGMPLTPSAIASSMQGSGPTFPSFHMPRYHHYFQQGPYAAIQGLR----------HSSAVMTPFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ES03-1", "uniprot_id": "TBX20_MOUSE", "id": "Q9ES03-1", "name": "T-box transcription factor TBX20", "aln": "---------------------------------------------------------------MEFTASPKPQLSSRANAFSIAALMSSG--GPKEKEAAENTIKPLEQF---------------VEKSSCAQP-----------------------------------------------------------LGELTSLDAHAEFGGGGGS-PSSSS--------------------------------LCTEP--LIPTTPIIP----SEEMAKIACSLETKELWDKFHELGTEMIITKSGRRMFPTIRVSFSG----VDPESKYIVLMDIVPVDNKRYRYAYHRSSWLVAGKADPPLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELDQHGHIILNSMHKYQPRVHIIKK---KDHTASLLNLKSEEFRTFIFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDIERESVESLIQKHSYARSPIRTYG--------------EEDVLGEESQTTQSRGSAFTTSDNLSLSSWVSSSSSFP-----------------GFQHPQPLTALGTSTASIATPIPHPIQGS----LPPYSRLGMPLTPSAIASSMQGSGPTFPSFHMPRYHHYFQQGPYAAIQGLR----------HSSAVMTPFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UMR3-1", "uniprot_id": "TBX20_HUMAN", "id": "Q9UMR3-1", "name": "T-box transcription factor TBX20", "aln": "---------------------------------------------------------------MEFTASPKPQLSSRANAFSIAALMSSG--GSKEKEATENTIKPLEQF---------------VEKSSCAQP-----------------------------------------------------------LGELTSLDAHGEFGGGSGSSPSSSS--------------------------------LCTEP--LIPTTPIIP----SEEMAKIACSLETKELWDKFHELGTEMIITKSGRRMFPTIRVSFSG----VDPEAKYIVLMDIVPVDNKRYRYAYHRSSWLVAGKADPPLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELDQHGHIILNSMHKYQPRVHIIKK---KDHTASLLNLKSEEFRTFIFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDIERESVESLIQKHSYARSPIRTYGG-------------EEDVLGDESQTTPNRGSAFTTSDNLSLSSWVSSSSSFP-----------------GFQHPQSLTALGTSTASIATPIPHPIQGS----LPPYSRLGMPLTPSAIASSMQGSGPTFPSFHMPRYHHYFQQGPYAAIQGLR----------HSSAVMTPFV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I9K7-1", "uniprot_id": "TBX20_DANRE", "id": "Q9I9K7-1", "name": "T-box transcription factor TBX20", "aln": "---------------------------------------------------------------MEYTSSPKPQLSSRANAFSIAALMSSG--KTKDKESEENTIKPLEQF---------------VEKSSCHPN-----------------------------------------------------------LGDLPPLETHSDFSSGGGT-GSGAP--------------------------------LCTEP--LIPTTPGVP----SEEMAKISCSLETKELWDKFHELGTEMIITKSGRRMFPTIRVSFSG----VDPDAKYIVLMDIVPVDNKRYRYAYHRSSWLVAGKADPPLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELDQHGHIILNSMHKYQPRVHIIKK---KDHTASLLNLKSEEFRTFVFTETVFTAVTAYQNQLITRLKIDSNPFAKGFRDSSRLTDIERESVESLIHKHSYARSPIRTYAG-------------DEETLGEEGHSAHSRGSAFTASDNLSLSSWVTTTSGFS-----------------GFQHPQSLSAIGTSTASLASPLPHPIQGS----LPPYSRLGMPLTPSALASSMQATGPTFPSFHMPRYHHYFQQGPYAAIQGLR----------HSSTVMTPFV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94890-1", "uniprot_id": "H15_DROME", "id": "Q94890-1", "name": "T-box protein H15", "aln": "MLLSNQPANTKPQQTPSPSQTQNFKSKLQQQIVSAAAAAAANIANGSSHHHHHQNHHHHHPLNNHHNHNHNQHNISFATDFSIAAIMARGGNAPSSREPSERSLSPASVERYSGQDADDDVDVDVVDCSDSEMPSATAAAAAAATTAAAAAAALQAQQQARQALRVAQQQQQQQQQQRQQTHHHATTGKQQRQHHNHHSSNTNNSSNSGNSNTNSKSSSQRGRSAAAVGAAATPSPPPPPPSQSPEELERLSPEESPAQQPTPKIVGSCNCDDLTPVQCHLETKELWDKFHELGTEMIITKSGRRMFPTVRVSFSGPLRQIQPADRYAVLLDVVPLDSRRYRYAYHRSSWLVAGKADPPPPSRIYAHPDCPLSPEALRKQVVSFEKVKLTNNEMDKSGQVVLNSMHRYQPRIHLVRLSHGQSIPGSPKELQDMDHKTFVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLSDFDRDPMDAFFFDQHMRTAPLRFFPDPLMSQLTPQEADAASMALLEKARQHLQMFG-RSPYTEMLLPHLYQRSAAPP-PPPPAPHLSAFQLGMWQQQWPQLTAGFLASANQQAALALAAAGAN---RTPPPSMAVAPPAPATPTSSCGSASPDLRARPQLN-HYPQRFSPYQVPQHQ-------ASPPASNRAESP--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMR2-1", "uniprot_id": "Q9VMR2_DROME", "id": "Q9VMR2-1", "name": "", "aln": "MLVGSHPYLCN----------------------GVPAAPAAPNASG------------------QTTTTASKSAAGSATDFSIAAIMAR--EDASSRESSIRSASPISVE--------DEVDVDVVDCSDAEEP-------------------------PTKARRLNHHQHHQHHQHHHNNNNNNNN--NNVAHKSRNSGGAVAQTASAESQLNTSSTSSQGR---------CSTPPQSPGTEDSE--ERLTPEP---VQKAPKIVGSCNCDDLKPVQCHLETKELWDRFHDLGTEMIITKTGRRMFPTVRVSFSGPLRQIQPADRYAVLMDIIPMDSKRYRYAYHRSAWLVAGKADPAPPARLYAHPDSPFSCEALRKQVISFEKVKLTNNEMDKNGQIVLNSMHRYQPRIHLVRLSHGQSIPSNPKELQDLDHKTYVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDFDRDPMEALLLEQQLR-SPLRLFPDPLMQQFAAQ-GDPSSMALFEKARQHLQMFGGNSPYAQLMMPQMYQAAAAAAGPPPPPPGLGAFH--MFQQQWPQLTAGFLASANQQAAAAQAAAQAQAQAQAAAAAMAANRTPPPPPTASTPSSTSSGSPSPDMRPRQYQRFSPYQLPGGQGPPSSAAGSPPAVNASRSPAH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . *. *****:*: ...:*. .: .* . *: *.. . . : . .. . : :. * .* :* : .::: : * ********:**:*********:*******:****** ::* :* **:*::*:*.:*********:*********. *:*:*.***.*:: * * **::***********:*: *:::*****:****:*::: :. ... :*:. :.:*::*.****************:******************:*::*:.::::: .: :*:* : . .* ::.: . . :. :: :. ::. . * ** :.: :*: . *: . .. .. : .*.. ::* .: . . . : : .** . :* ", "identical_positions": 158, "similar_positions": 147, "identity": "23.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000501-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4QQT3-1", "uniprot_id": "CELF1_RAT", "id": "Q4QQT3-1", "name": "CUGBP Elav-like family member 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNGTLDHP-------------------------------------------------------DQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINILRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRTMAQTAIKA-MHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQ-----------------------------------------------LQQQMQQISAASVWGNLAGLN-------TLGPQYLAL----------------------YLQLLQQTANSGN-----LNTLSSLHP--MGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSSA----------------GSSPSSSSSNSVNPIASLGALQTLAG---------------ATAGLN--------------VGSLAGMAALNGGLGSSGLSNGTGS--TMEALTQ---------AYSGIQQYAAA-ALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28659-1", "uniprot_id": "CELF1_MOUSE", "id": "P28659-1", "name": "CUGBP Elav-like family member 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNGTLDHP-------------------------------------------------------DQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINILRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRTMAQTAIKA-MHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQ-----------------------------------------------LQQQMQQISAASVWGNLAGLN-------TLGPQYLAL----------------------YLQLLQQTASSGN-----LNTLSSLHP--MGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSS-----------------GSSPSSSSSNSVNPIASLGALQTLAG---------------ATAGLN--------------VGSLAGMAALNGGLGSSGLSNGTGS--TMEALTQ---------AYSGIQQYAAA-ALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92879-1", "uniprot_id": "CELF1_HUMAN", "id": "Q92879-1", "name": "CUGBP Elav-like family member 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNGTLDHP-------------------------------------------------------DQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKA-MHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQ-----------------------------------------------LQQQMQQISAASVWGNLAGLN-------TLGPQYLAL----------------------YLQLLQQTASSGN-----LNTLSSLHP--MGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSS-----------------GSSPSSSSSNSVNPIASLGALQTLAG---------------ATAGLN--------------VGSLAGMAALNGGLGSSGLSNGTGS--TMEALTQ---------AYSGIQQYAAA-ALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9IBD0-1", "uniprot_id": "CELF1_DANRE", "id": "Q9IBD0-1", "name": "CUGBP Elav-like family member 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNGSLDHP-------------------------------------------------------DQPDIDSIKMFVGQIPRTWSEDQLRELFEPYGAVYEINVLRDRSQNPPQSKGCCFVTYYTRKSALEAQNALHNMKILPGMHHPIQMKPADSEKNNAVEDRKLFVGMISKKCNENDIRLMFSPYGQIEECRILRGPDGLSRGCAFVTFTARQMAQSAIKS-MHQSQTMEGCSSPIVVKFADTQKDKEQKRIAQQ-----------------------------------------------LQQQMQQLNAASMWGNLTGLN-------SLGPQYLAL----------------------YLQLLQQSASSG-------NALNNLHP--MSGLNAMQ--NLAALAAAASATQATPTGSSALTTSSSPLSVLTSSGTPSGQPAQSAWDAYKAGSSPTSSTSSSVNPMASLGALQSLAAG--------------AGAGLN--------------MSSLASMAALNGGLGSGGLSNGSGS--TMEALTQA--------AYSGIQQYAAA-ALPSLYSQSLLSQQNVSAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSSQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0E8R3-1", "uniprot_id": "Q0E8R3_DROME", "id": "Q0E8R3-1", "name": "", "aln": "MMLQSLSLHADKLSGNSPAAAAATG------------------------------AAAATSEATAVASAAAATTMLATAPVAH--VANGNNSNSSAGSSSNSNSSSNNHSLYSNNNLNTGNNSQQQQQQQQQHPQILPVK------------YEYLENLTSSGATSGAIAATTT----FTGAAKSFHPYLRP-------------TGSGSNSNNSIAALSTTTAATAAKMSTTLFETLLHNQINSSPIALPAATAIAAISAAATAATATPGTAATAAAAAAAAPSTQLNSSINSRTS--LGDQGGAIVVVTPAPPVAAPPTGGPNRNQSPTRDCSVKMELMESTSPDSIKDQPDADNIKMFVGQIPKTWDETRLRQMFEQFGPVHTLNVLRDKVTS--ISRGCCFVTYYTRKAALRAQDALHNIKTLDGMHHPIQMKPADSENRN---ERKLFVGMLNKKYTEADVRQLFTGHGTIEECTVLRDQAGQSKGCAFVTFATKQNAIGAIKA-LHQSQTMEGCSAPLVVKFADTQKEKDQKKMQQIHAFCGINTPSGATAGAATPTINAATALIAAPPSAGRTNPSMAAALAAVPQVQQAGSAATAPTTLVPLNSTTALSASLTPNLLATNAAHQGAAAAAAYLGADPAAAAHLQLYQQLHGYGLSPAHYLPGLNFHHPPENSAHHSQHSPGIGGASAASLSAAAATAASNPLGGAPPPTPTPTSSAGHAAGAG--------LLAAPSMSMQNLVALLATPTAHHQLSLHHSSSSSGHNNGNSSATSGLHNQRLTYAAAPPPPPISTTYNMPQLIGHTATPTQPGGSSQSLTFNALWPPNAADPYSSSLSGLTNGAAYGAASQPVTTSALQAAAAGVTGKQIEGPDGSNLFIYHLPQEFIDTDLASTFLPFGNVLSAKVFIDKQTNLSKCFGFVSYDNPHSANAAIQAMHGFQIGSKRLKVQLKRSKDAAKPY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IP90-1", "uniprot_id": "Q8IP90_DROME", "id": "Q8IP90-1", "name": "", "aln": "-MLSSLDALAGKIATATPGTGAVTADSKNTQSLHHHHRLDYDYSAVEIEPPAEQLANSPRSERERLQQAQQAYEQQAQAELEFGLAEVDAKLTQLKSSHSLQHHHSHHHQLQRHTALNQQQQQLHHHQPHHNHHHHHPYQRPRPTSPPQQQTSSYQQQLSQLAALQDHHDLLQTQQELFHKQLATMQEYQRERERERERERERERERERERDRSSFIDNSDYDSQTEFKICLRDSAFGMSDKSSSATNSLPNSPIHSNNNNPSLLNNNNNNSNGTSSNNSLNVGNNNSNPSLGGSNSNALVSVGSNGIMSAAGLVNNNNNPCSANRNVVAMVDDDACFRLDTDATVTYGEKEPDPDNIKMFVGQVPKSMDESQLREMFEEYGAVHSINVLRDKATG--ISKGCCFVTFYTRHAALKAQDALHNVKTLNGMYHPIQMKPADSENRN---ERKLFVGMLNKKLNENDVRKLFEVHGAIEECTVLRDQNGQSKGCAFVTFATKHAAISAIKVTLSQNKIMEGCTSPLVVKFADTQKEKEQKKIQQI-----------------------------------------------QANLWNLASNINIPLGQTATS-------VTTPILPNP----------------------PQQPSPVLGADAITP----ASIQLLQQLQAVGLQHQLLQALTGLGAQQSSSATDTSAVAAAG-LLTPMTVQNLAAIAA-------------MTQPSLSNAAAAAAAATSPGSAQLTN----------------TAALL--------------WSDPNPMASAYMSTAAGLPQFGSAS------------------ALST-----------SPLASVALSAAAAAAAGKQIEGPEGCNLFIYHLPQEFTDTDLASTFLPFGNVISAKVFIDKQTSLSKCFGFVSFDNPDSAQVAIKAMNGFQVGTKRLKVQLKKPKD-SKPY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::. .:** * *******:*:: .* **::** :*.*: :*:***: . *:******:***::**.**:****:* * **:***********:.* :****:**:.** .* *:* :* .* **** :**. * *:*******::: * *** : * : ****::*:*********:*:**:: * : : . . . . * * . :. : . : : . .* :: .:. . .* .. . : : *: * . *: . *: :.* . *. .: *:.. : * * ..:*.* ***:*.*********** * ** . *:*****:**********.*********:*** *::.**::*:***:* ********:.*: :***", "identical_positions": 189, "similar_positions": 115, "identity": "19.48%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000501-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AGJ7-1", "uniprot_id": "A0A8I6AGJ7_RAT", "id": "A0A8I6AGJ7-1", "name": "CUGBP Elav-like family member 3", "aln": "MKEPDAIKLFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPADSESRGE--DRKLFVGMLGKQQTDEDVRKMFEPFGTIDECTVLRGPDGTSKGCAFVKFQTHAEAQAAINTLHSSRTLPGASSSLVVKFADTEKERGLRRMQQVATQLGMFSPIAL-QFGAYSAYTQ-----ALMQQQAALVAAHSAYLSPMATMAAVQMQHMAAINANGLIATP---ITPSS--GTSTP---PAIAATPVSAIPAALGVNGYSPVPTQPTGQPAPDALYPNGVHPYPDEALSAERSAGEAPIMPQTHSWLVMLSAAQSPAAPVDPLQQAYAGMQHYT-AAYPAAYSLVAPAFPQPPALVAQQPPPPPQQQQQQQQQQQQQQQQQQQQQQQREGPDGCNIFIYHLPQEFTDSEILQMFVPFGHVISAKVFVDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CIN6-1", "uniprot_id": "CELF3_MOUSE", "id": "Q8CIN6-1", "name": "CUGBP Elav-like family member 3", "aln": "MKEPDAIKLFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPADSESRG---DRKLFVGMLGKQQTDEDVRKMFEPFGTIDECTVLRGPDGTSKGCAFVKFQTHAEAQAAINTLHSSRTLPGASSSLVVKFADTEKERGLRRMQQVATQLGMFSPIAL-QFGAYSAYTQ-----ALMQQQAALVAAHSAYLSPMATMAAVQMQHMAAISANGLIATP---ITPSS--GTSTP---PAIAATPVSAIPAALGVNGYSPVPTQPTGQPAPDALYPNGVHPYP----------------------------AQSPAAPVDPLQQAYAGMQHYT-AAYPAAYSLVAPAFPQPPALVAQQPPPPPQQQQQQQQQQQQQQQQ-------REGPDGCNIFIYHLPQEFTDSEILQMFVPFGHVISAKVFVDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SZQ8-1", "uniprot_id": "CELF3_HUMAN", "id": "Q5SZQ8-1", "name": "CUGBP Elav-like family member 3", "aln": "MKEPDAIKLFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPADSESRGE--DRKLFVGMLGKQQTDEDVRKMFEPFGTIDECTVLRGPDGTSKGCAFVKFQTHAEAQAAINTLHSSRTLPGASSSLVVKFADTEKERGLRRMQQVATQLGMFSPIAL-QFGAYSAYTQ-----ALMQQQAALVAAHSAYLSPMATMAAVQMQHMAAINANGLIATP---ITPSS--GTSTP---PAIAATPVSAIPAALGVNGYSPVPTQPTGQPAPDALYPNGVHPYP----------------------------AQSPAAPVDPLQQAYAGMQHYT-AAYPAAYSLVAPAFPQPPALVAQQPPPPPQQQQQQQQQQQQQQQR--------EGPDGCNIFIYHLPQEFTDSEILQMFVPFGHVISAKVFVDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9IBD1-1", "uniprot_id": "CELF3_DANRE", "id": "Q9IBD1-1", "name": "CUGBP Elav-like family member 3", "aln": "MKEADAIKLFIGQIPRNLEEKDLKPIFEQFGKIYELTVIKDKYTGMHKGCAFLTYCARESALKAQNALHEQKTLPGMNRPIQVKPADSEGRG---DRKLFVGMLGKQLSDADVRKMFEPFGSIEECTVLRGPDGASKGCAFVKYQSNAEAQAAISALHGSRTLPGASSSLVVKFADTEKERGIRRMQQVASQLGVISPMSL-HLGAYNAYTQ-----ALVQQQA--LVAQSAYLSPVATVAAVQMQQLAALNPSSIIATPIASITPSS--GTSTP---PTIAATPVPALPPPIAVNSYPPVPAAPNGQSASEALYTNGVHPYQ----------------------------AQSPAL--DPLQQAYTGMQHYT-ATYPAAYGLVGQPFPHQPTLVAQQP-----------QQPQQLQQR--------EGPEGCNIFIYHLPQEFTDSEMLQMFLPFGNVISAKVFVDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A6M3Q6L8-1", "uniprot_id": "A0A6M3Q6L8_DROME", "id": "A0A6M3Q6L8-1", "name": "", "aln": "----------------------MVHIIELVG-------------------------------QPKVEFAQQVT---MNRALQLKPAENESRSEHLDRKLFVGMLSKQQTEDDVRQIFHPFGTIEECTILRGPDGASKGCAFVKFGSQQEAQSAITNLHGSQTMPGASSSLVVKYADTEKERQIRRMQQMAGHMNLLNPFVFNQFSPYGAYAQQQQQAALMAAAATAPGSAAAYMNPMAALATQIPHGLNGTGQPPSLPSP---TMPNFNMGANTPNGQPGGAAAAAAAAAAADGVFTNGIPQTAFPGHPLHLTIPPQGLPNGD-----------------------------------AATLQHAFPGLPPFPGVAFPAVYGQFPQALPPPLAAVAPTQ-----------REDFLMFPG-----CSISGPEGCNLFIYHLPQEFGDAELMQMFLPFGNVISSKVFIDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDASRPYXQSEFLKRNSQQPTGATTSATGALPTTTAFSAATPTSAVTSVSATVTTTAHYNNLGSSFRPTLPLPTESSNHNAHIPYTFASWRSGTYCYRNHNNNSENYSDNNNNHRNVPDSQSQNDTSSNTNCSKVELVERLFMWQQQKRKA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:* .* :.: : :* * ***.:*:***:.*.*. *********.** :: ***::*.***:*:***:******:********: :: ***:**. **.*:*:**********:******* :*****:* ::.::.*: : ::..*.**:* **: * : :**:.*:*::*: : : . . :.:* *. *:.** * **:...* ... .* : *:. :: .:*: .**:*:.*: :. .::**.*. . .:* : ** :: .**:***:********* *:*::***:***:***:***:************************************************.*** ", "identical_positions": 196, "similar_positions": 114, "identity": "29.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000509-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8WYA1-1", "uniprot_id": "BMAL2_HUMAN", "id": "Q8WYA1-1", "name": "Basic helix-loop-helix ARNT-like protein 2", "aln": "MAAEEEAAAGG-KVLREENQCIAPVVSSRVSPGTRPTAMGSFSSHMTEFPRKRKGSDSDPSQSGIMTEKVVEKLSQNPLTYLLSTRIEISASSGSRVEDGEHQVKMKAFREAHSQTEKRRRDKMNNLIEELSAMIPQCNPMARKLDKLTVLRMAVQHLRSLKGLTNSYVGSNYRPSFLQDNELRHLILKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAKVKEQLSSFDISPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHGCLP-NSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKKDNSNFTCLVAIGRLQPYIVPQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLTDKHKAVLQSKEKILTDSYKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVSVNTLVLGHSEPGE-ASFLPC--SSQSSEESSRQS--CMSVPGMSTGT-VLGAGSIGTDIANEILDLQRLQSSSYLDDSSPTGLMKDTHTVN----CRSMSNKELFPPSPSEMGELEATRQNQSTVAVHSHEPLLSDGAQLDFD-----ALCDNDDTAMAAFMNYLEAEGGLGDPGDFSDIQWTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2VPD4-1", "uniprot_id": "BMAL2_MOUSE", "id": "Q2VPD4-1", "name": "Basic helix-loop-helix ARNT-like protein 2", "aln": "----------------------------------------------MEFPRKRRGRDSQPLQSEFMTDTTVESLPQNPFASLLSTRTGVSAPSG--------------IREAHSQMEKRRRDKMNHLIQKLSSMIPPHIPTAHKLDKLSVLRRAVQYLRSLRGMTELYLGENSKPSFIQDKELSHLILKAAEGFLFVVGCERGRIFYVSKSVSKTLRYDQASLIGQNLFDFLHPKDVAKVKEQLS-CDGSPREKPIDTKT-SQVYSHPYTGRPRMHSGSRRSFFFRMKSCTVPVKEEQPCSS-CSKKKDHRKFHTVHCTGYLRSWPLNVVGMEKESGGGKDSGPLTCLVAMGRLHPYIVPQKSGKINVRPAEFITRFAMNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHSSLTDKHKAVLQSKEKILTDSYKFRVKDGAFVTLKSEWFSFTNPWTKELEYIVSVNTLVLGRSETR--LSLLHCGGSSQSSEDSFRQS--CINVPGVSTGT-VLGAGSIGTDIANEVLSLQRLHSSS-PEDASPSEEVRDDCSVNGGNAYGPASTREPFAVSPSETEVLEAARQHQSTEPAHPHGPLPGDSAQLGFD-----VLCDSDSIDMAAFMNYLEAEGGLGDPGDFSDIQWAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IH97-1", "uniprot_id": "A0A0R4IH97_DANRE", "id": "A0A0R4IH97-1", "name": "", "aln": "MSSRNTAAGGGDGATGENTGDVLEEEPQGLSASLSGLMTPTSASSLMELPRKRKGSMDN------LEMKSASNLDEDMEDDAGRSEDDQHLKIK-------------CIREPHSQIEKRRRDKMNNLIDELAAMIPTCNPMSRKLDKLTVLRMAVQHLKSLKGATSSFAEANYKPAFLPDDELKHLVLRAADGFLFVVGCDRGKIVFVSESVSKTLNYSRTELIGQSLFDYVHPKDIGKVKEQLSASELYPRERLIDAKTGLQVQAELPVGSARLCSGARRSFFCRMKYNKITVKEEKDFQAGASKKKESQRYCTVHCTGYMRTWPTRQLATEGEAEADKESSHFSCLVAMGRVHPHTLPQANGEIKVKPTEFVTRYAMDGKFTFVDQRATTILGYLPQELLGTSCYEYFHLDDLPHLAERHRKVLRSKEKIETNCYKFKTKSGSFVNLQSQWFSFINPWTKEVEYIVSTNTVVSGKSNPGGSGDKAEQPSSSKASEDDAKKSQQVPIIPGISSASGMIYAGCIGTQIANEIMDFNRMNSSPSSGNTSPFSLLQDKSPLA---LAQASSNVPNGEATDVEMPGKSSSEEEARGGPFSTGDNLMEASSQLDLEGVPGLGALSTDEAAMAVIMSLLETDANLGEAVNFDEMHWSL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:****:* .: : . ...* :: :. :**.*** *********:**::*::*** * ::*****:*** ***:*:**:* *. : * :*:*: *.** **:*::*:********:**:*.:**:**** *.*.::.* **.***::****:.******* : ***: **:** ** :. .* .*: **:***** *:* .:.****: . ****: ::: *:*****:*:** . :. * * . *:.. ::****:**::*: :** .*:*:*:*:**:**:*::***.:******:******************* ** *:::*: **:***** *:.***:.*.*:**.*:*:**** ******:*****.**:* *:*:. . **::**:. ::* :**:*:.: :: **.***:****::.::*::**. ::** ::* .: . *. : * .::.:. . . * .:**.:: ..*. **.:*. **::..**:. :*.:::*:*", "identical_positions": 256, "similar_positions": 183, "identity": "39.2%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000511-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61295-1", "uniprot_id": "HAND2_RAT", "id": "P61295-1", "name": "Heart- and neural crest derivatives-expressed protein 2", "aln": "MSLVGGFPHHPVVHHEGYPFAAAAAAAAAAAASRCSHEENPYFHGWLIGHPEMSPPDYSMALSYSPEYASGAAGLDHSHYGGVPPGAGPPGLGGPRPVKRRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKD-DQNGEAEAFKAEIKKTDVKEEKRKKELNEILKSTVSSNDKKTKGRTGWPQHVWALELKQ---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61039-1", "uniprot_id": "HAND2_MOUSE", "id": "Q61039-1", "name": "Heart- and neural crest derivatives-expressed protein 2", "aln": "MSLVGGFPHHPVVHHEGYPFAAAAAAAAAAAASRCSHEENPYFHGWLIGHPEMSPPDYSMALSYSPEYASGAAGLDHSHYGGVPPGAGPPGLGGPRPVKRRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKD-DQNGEAEAFKAEIKKTDVKEEKRKKELNEILKSTVSSNDKKTKGRTGWPQHVWALELKQ---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61296-1", "uniprot_id": "HAND2_HUMAN", "id": "P61296-1", "name": "Heart- and neural crest derivatives-expressed protein 2", "aln": "MSLVGGFPHHPVVHHEGYPFAAAAAAAAAAAASRCSHEENPYFHGWLIGHPEMSPPDYSMALSYSPEYASGAAGLDHSHYGGVPPGAGPPGLGGPRPVKRRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKD-DQNGEAEAFKAEIKKTDVKEEKRKKELNEILKSTVSSNDKKTKGRTGWPQHVWALELKQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P57102-1", "uniprot_id": "HAND2_DANRE", "id": "P57102-1", "name": "Heart- and neural crest derivatives-expressed protein 2", "aln": "MSLVGGFPHHPVMHHDGYSFA------AAAAASRC-HEEPPYFHGWLISHPEMSPPDYTMAPSYSPEYSTGAPGLDHSHYGGVP-GAGAVGMG-PRTVKRRPTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDILDKD-EQNGETEAFKAEFKKTDAKEERRKKEMNDVLKSSGSSNDKKTKGRTGWPQHVWALELKQ---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VL05-1", "uniprot_id": "Q9VL05_DROME", "id": "Q9VL05-1", "name": "", "aln": "------------MFKN-------------SVALTC--EYSTMYYNSIYNTSNMFDMKHSESQVQQQIYNT-------SHLGYVP-------TSNTRIVKKRNTANKKERRRTQSINNAFSYLREKIPNVPTDTKLSKIKTLKLAILYINYLVNVLDGDLDPKG---GFRAELKPVSRKICSEKK---HCLKSEIQNVPLSTKGRTGWPQDVWASELIPEHN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:: :.* * * . ::. : . .:* .:: : . * : ** * ** . .* **:* ***:**********.**: *** *****:**********:** ** **:::* * : :* .*:**:* .. * .** . *** .. .*********.*** ** ", "identical_positions": 80, "similar_positions": 44, "identity": "36.2%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000511-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V8L1-1", "uniprot_id": "G3V8L1_RAT", "id": "G3V8L1-1", "name": "Apoptosis-associated speck-like protein containing a CARD", "aln": "-MGRARDAILDALENLTADEFKKFKMKLLTAPVREGYGRIPRGALLQM-DPIDLTDKLVSYYLEGYGLELTMTVLRDMGIQELAEQLQKIMEE-------SGAVATATSVPAQGTARTE-HFVDQHRQALIARVTEVDGLLDALYG-NVLTEGQYQAVRAETTNQNKMRKLFS-FAPAWNLTCKNLFLEALRQTQPYLVTDLEQS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPB4-1", "uniprot_id": "ASC_MOUSE", "id": "Q9EPB4-1", "name": "Apoptosis-associated speck-like protein containing a CARD", "aln": "-MGRARDAILDALENLSGDELKKFKMKLLTVQLREGYGRIPRGALLQM-DAIDLTDKLVSYYLESYGLELTMTVLRDMGLQELAEQLQTTKEE-------SGAVAAAASVPAQSTARTG-HFVDQHRQALIARVTEVDGVLDALHG-SVLTEGQYQAVRAETTSQDKMRKLFS-FVPSWNLTCKDSLLQALKEIHPYLVMDLEQS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULZ3-1", "uniprot_id": "ASC_HUMAN", "id": "Q9ULZ3-1", "name": "Apoptosis-associated speck-like protein containing a CARD", "aln": "-MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSM-DALDLTDKLVSFYLETYGAELTANVLRDMGLQEMAGQLQAATHQG------SGAAPAGIQAPPQSAAKPGLHFIDQHRAALIARVTNVEWLLDALYG-KVLTDEQYQAVRAEPTNPSKMRKLFS-FTPAWNWTCKDLLLQALRESQSYLVEDLERS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I9N6-1", "uniprot_id": "ASC_DANRE", "id": "Q9I9N6-1", "name": "Apoptosis-associated speck-like protein containing a CARD", "aln": "MAESFKEHLQEAFEDLGADNLRKFKSKLGDRRQEP---RVTKSAIEKLKDEIDLADLMVGVFTSKDAVSVTVEILRAIKCNAVADDLLRNTGQSESKGALSDESKCASSKAVSKVAFSKVNFIDEHWKELIDRVNNVDPILDILRQKKVITNEDYCTIRNKETPQKKMRELLTGPITCAGNKGKEVLYDALRESNKFLMDDLEDAE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : :*:*:* .::::*** ** . *:.:.*: .: * :**:* :*. : . . .:* :** : : :* :* : *. . . . . .* . :*:*:* ** **.:*: :** * .*:*: :* ::* : * .***:*:: .. . . *: : :**:: : :*: *** : ", "identical_positions": 49, "similar_positions": 72, "identity": "23.79%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000511-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QX67-1", "uniprot_id": "DAP1_RAT", "id": "Q9QX67-1", "name": "Death-associated protein 1", "aln": "MSSPPEGKLETKAGHPPAVKVAGIRIVQKHPHTGDGKEKKD-KDDQEWESTSPPKPTVYISGVIARGDKDFPPAAAQVAHQKPHASMDKHVSPR--TQHIQQPRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XC8-1", "uniprot_id": "DAP1_MOUSE", "id": "Q91XC8-1", "name": "Death-associated protein 1", "aln": "MSSPPEGKLETKAGHPPAVKAGGMRIVQKHPHTGDGKEERD-KDDQEWESTSPPKPTVFISGVIARGDKDFPPAAAQVAHQKPHASMDKHVSPR--TQHIQQPRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51397-1", "uniprot_id": "DAP1_HUMAN", "id": "P51397-1", "name": "Death-associated protein 1", "aln": "MSSPPEGKLETKAGHPPAVKAGGMRIVQKHPHTGDTKEEKD-KDDQEWESPSPPKPTVFISGVIARGDKDFPPAAAQVAHQKPHASMDKHPSPR--TQHIQQPRK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I9N1-1", "uniprot_id": "DAP1A_DANRE", "id": "Q9I9N1-1", "name": "Death-associated protein 1 homolog", "aln": "MSSPPKEKTETRAGHLPAVKAGGMRIVQKHQSAIEVPDKKDDKDSTEYETVIPPKLPVVVSGVVTKGDKDFTPAAAQVAHQKPVPSAQKLPAGQHLNQHIHQPRK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****: * **:*** ****..*:****** : : :::* **. *:*: *** .* :***:::*****.*********** .* :* : : .***:****", "identical_positions": 59, "similar_positions": 25, "identity": "56.19%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000511-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FMI3-1", "uniprot_id": "F7FMI3_RAT", "id": "F7FMI3-1", "name": "", "aln": "MGQLQLALSLRAPTRHWHTDTMANEVQVLSSPLKGRHAPAVKAGGMRISKK--QEMGVLERHTKKTGLEKTSAITNVAKIQMLDTLTD-TLDKLHHKFPAT-VHTAHQKPTPALEKAAPLKRAYIIQQPRKC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D757-1", "uniprot_id": "DAPL1_MOUSE", "id": "Q9D757-1", "name": "Death-associated protein-like 1", "aln": "---------------------MANEVQVLPSPLKGRYAPAVKAGGMRISKK--QEMGVLERHTKKTGLEKTSAITNVAKIQMLDALTD-TLDKLNHKFPAT-VHTAHQKPTPALEKAAPMKRAYIIQQPRKC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0PJW8-1", "uniprot_id": "DAPL1_HUMAN", "id": "A0PJW8-1", "name": "Death-associated protein-like 1", "aln": "---------------------MANEVQDLLSPRKGGHPPAVKAGGMRISKK--QEIGTLERHTKKTGFEKTSAIANVAKIQTLDALND-ALEKLNYKFPAT-VHMAHQKPTPALEKVVPLKRIYIIQQPRKC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I9N0-1", "uniprot_id": "DAP1B_DANRE", "id": "Q9I9N0-1", "name": "Death-associated protein-like 1 homolog", "aln": "--------------------MVQLSKTGVRDTLKAGHPPAVKAGGKRVVKKSADENANVEKETRKT--DKPRSVLAPSRMQHLSLLLSGPLEKLGHDFPETPVSVRHSRVRPSVEKPH-ISRIPCIQQPRKF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : .. *. :.******* *: ** :* . :*:.*:** :*. :: :::* *. * . .*:** :.** * * *.: *::** :.* ****** ", "identical_positions": 38, "similar_positions": 34, "identity": "28.79%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000511-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZC5-1", "uniprot_id": "D3ZZC5_RAT", "id": "D3ZZC5-1", "name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "aln": "--------MAADQNGHEEWVGSAYLFLESSMDKVVLSEAYTDPKKKVAIYKALQAALSESGDSPDVLQILKIHCSDPQLIVQLRFCGRLLCGRFLQAYREGALRTALQRCMAAALAQ-EAVRLQLELRAGAEQLDSWLTDEERCLNYILAQKPDRLRDEELAELEDEFCKLTCDSTGQGGATQVAPAGSKSLVSSPAEEKP--LPAAGQTFLFHGQLIVNRPLNLQDQQTFARSVGLKWRRVGRSLQRSCRALRDPALDSLAYEYERDGLYEQAFQLLRRFIQAEGRRATLQRLVEALEENELTSLAEDLLGQAEPEGGQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U0V2-1", "uniprot_id": "TRADD_MOUSE", "id": "Q3U0V2-1", "name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "aln": "--------MAAGQNGHEEWVGSAYLFLESAVDKVILSEAYTDPKKKVAIYKALQTALSESGDSSDVLQILKIHCSDPQLIVQLRFCGRVLCGRFLQAYREGALRTALQRCMAPALAQ-EALRLQLELRAGAEQLDSWLTDEERCLNYILAQKPDRLRDEELAELEDELCKLTCDCTGQGGAIQVASAGSKFPVSSPTEEKP--LPAACQTFLFHGQLVVNRPLTLQDQQTFARSVGLKWRRVGRSLQRNCRALRDPALDSLAYEYERDGLYEQAFQLLRRFMQAEGRRATLQRLVEALEENELTSLAEDLLGQAEPDGGLA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15628-1", "uniprot_id": "TRADD_HUMAN", "id": "Q15628-1", "name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "aln": "--------MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQ-HSVPLQLELRAGAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRGCRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAEDLLGLTDPNGGLA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I9N5-1", "uniprot_id": "TRADD_DANRE", "id": "Q9I9N5-1", "name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "aln": "MDSIDTKRLNDSNASDRALSGCAVLFLGCSSLEHNFLSLYKDERGKFSVFKVIKLTLSDSVGGLEGYEILKLHDADPYLGVELKFMAMPPCQRFLESYACGSLTQFLSQHASRLLALPDGVEIETQLKAGVHTLDHSLQDIEICLDHIRQSQPVRLRDDEVTQLEQQLQN------------------SYGPPSQPPQELP------RNCFLFQKRVFDDRPLTPADQQRFAAHVGRDWKRVGRALQKNCRALKGPAIDNLAYEYEREGLYEQAYQLLGRFIQSEGRSAKLSRLISALEETKMTSMAEIMLGIQPRD----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: ... *.* **: .: : : . * . : *.::::.:: :*::* .. : ::**:* :** * *:*:* . * ***.:* *:* *.: : ** ..: :: :*:**.. ** * * * **. * .:* ****:*:::**: : : .. .: * : ***: : . :***. *** ** ** .*::***:**:.****:.**:*.*******:******:*** **:*:*** *.*.**:.****.::**:** :** : ", "identical_positions": 109, "similar_positions": 95, "identity": "33.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000511-8", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q923U9-1", "uniprot_id": "S40A1_RAT", "id": "Q923U9-1", "name": "Ferroportin", "aln": "MTKSRDQTHQEGCCGSLANYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLLTAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKNELLNMYHGWVLTVCYILIITIANIANLASTATAITIQRDWIVVVAGENRSRLADMNATIRRIDQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYFLLWKVYQKTPALAVKAALK-VEESELKQLTSPKDTE--PKPLEGTHLMGEKDSNIRELECEQEPTCASQIAEPFRTFRDGWVSYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSVLMGASAITGIMGTVAFTWLRRKCGLVRTGLFSGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFIHEEA--VSSTTKIPET--EMLMSNVSNVVNTVHEMSTKSVPIISVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHLMYFRFAQKTLGNQIFV-CAPDEKEVTDESQPNTSVV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHI9-1", "uniprot_id": "S40A1_MOUSE", "id": "Q9JHI9-1", "name": "Ferroportin", "aln": "MTKARDQTHQEGCCGSLANYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLLTAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKNELLTMYHGWVLTVCYILIITIANIANLASTATAITIQRDWIVVVAGENRSRLADMNATIRRIDQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYFLLWKVYQKTPALAVKAALK-VEESELKQLTSPKDTE--PKPLEGTHLMGEKDSNIRELECEQEPTCASQMAEPFRTFRDGWVSYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAFTWLRRKCGLVRTGLFSGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFVNVEP--VSPTTKIPET--VFTTEMHMSNMSNVHEMSTKPIPIVSVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHLMYFRFAQKTLGNQIFV-CGPDEKEVTDENQPNTSVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NP59-1", "uniprot_id": "S40A1_HUMAN", "id": "Q9NP59-1", "name": "Ferroportin", "aln": "MTRAGDHNRQRGCCGSLADYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLLTAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKHELLTMYHGWVLTSCYILIITIANIANLASTATAITIQRDWIVVVAGEDRSKLANMNATIRRIDQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYVLLWKVYQKTPALAVKAGLK-EEETELKQLNLHKDTE--PKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWVSYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAFTWLRRKCGLVRTGLISGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFIQGES--ITP-TKIPEITTEIYMSNGSNSANIVPETSPESVPIISVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHIMYFRFAQNTLGNKLFA-CGPDAKEVRKENQANTSVV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I9R3-1", "uniprot_id": "S40A1_DANRE", "id": "Q9I9R3-1", "name": "Solute carrier family 40 member 1", "aln": "MDSPASKKPR---CERFREFFKSAKFLIYVGHALSTWGDRMWNFAVAVFLVELYGNSLLLTAVYGLVVAGSVLLLGAIIGDWVDKNPRLKVAQTSLVVQNSAVILCGALLMAVFQFKQQLSSMYDGWLLTTCYIMVISIANIANLASTAMSITIQRDWVVVVAGDDRSKLADMNATVRIIDQLTNILAPMLVGQIMAFGSHFIGCGFISGWNLFSMCLEYFLLWKVYQKTPALAFKAGQKDSDDQELKHLNIQKEIGNTESPVEASQLMTESS------ETKKDTGCCYQMAEPIRTFKDGWVAYYNQSIFFAGMSLAFLYMTVLGFDCITTGYAYTQGLNGSVLSLLMGASAVSGICGTVAFTWIRKKCGLIRTGFIAGVTQLSCLTLCVASVFAPGSPFDLSVSPFEEVLRHLFGDSGSLRESPTFIPTT------EPPIQANVTVFEEAPPVESYMSVGLLFAGVIAARVGLWSFDLTVTQLIQENVIESERGVINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVIISVSFVAMGHMMYFRFAYKSLGSRLFLFCSPEQKPDPNIPSLPNSV-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . .:. : * : :::.*****:*:**:*********:***:**************************:************.************* :***** :** ** .*::* .**.**:** ***::*:*********** :*******:*****::**:**:****:* *********** *****:*** .***********.***:**.*************.**. * :: ***:*. *: .*:*.::** .. * :::. *. *:***:***:****:****.:*:***.************************.**:**:******::** *******:*:****:***:::*::***** *** *** ****:********:: ::. . . * ** . . * * :. . :**.**********:************:**********:*********************************:**********:****** ::**.::* *.*: * . . .** ", "identical_positions": 378, "similar_positions": 110, "identity": "65.4%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000526-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7S6-1", "uniprot_id": "G3V7S6_RAT", "id": "G3V7S6-1", "name": "", "aln": "-------------------------------------MKRPCEETTSES---------------DLDETIDVGSENNYSGHSASSVMRSNSPTTTSQIMARKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGY-FDAHALATDFMSIGFRECLTEVARYLSSVEGLDPSDPLRVRLVSHLSTCASQREAAVMTSS-----------------------MSHHHHPLHPHHWAAAFHHLPTSLLQPNGLHTSESTPCRLSTSSEVPPAHGSALLTATFAHADSALRMPSTG-----------TVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPSNAAAAAAVAAATAISPPLSVSAASSPQQTSSGTNSKPYRPWGTEVGAF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QUS4-1", "uniprot_id": "HEY2_MOUSE", "id": "Q9QUS4-1", "name": "Hairy/enhancer-of-split related with YRPW motif protein 2", "aln": "-------------------------------------MKRPCEETTSES---------------DLDETIDVGSENNYPGHATSSVMRSNSPTTTSQIMARKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGY-FDAHALATDFMSIGFRECLTEVARYLSSVEGLDPSDPLRVRLVSHLSTCASQREAAVMTSS-----------------------MAHHHHPLHPHHWAAAFHHLPTALLQPNGLHTSESTPCRLSTSSEVPSAHGSALLTATFAHADSALRMPSGG-----------TVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPSNAAAAAAVAAATAISPPLSVSAASSPQQTSTGTNNKPYQPWGTEVGAF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBP5-1", "uniprot_id": "HEY2_HUMAN", "id": "Q9UBP5-1", "name": "Hairy/enhancer-of-split related with YRPW motif protein 2", "aln": "-------------------------------------MKRPCEETTSES---------------DMDETIDVGSENNYSGQSTSSVIRLNSPTTTSQIMARKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGY-FDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSS-----------------------MAHHHHPLHPHHWAAAFHHLPAALLQPNGLHASESTPCRLSTTSEVPPAHGSALLTATFAHADSALRMPSTG-----------SVAPCVPPLSTSLLSLSATVHAAAAAATAAAHSFPLSFAGAFPMLPPN--AAAAVAAATAISPPLSVSATSSPQQTSSGTNNKPYRPWGTEVGAF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I9L0-1", "uniprot_id": "HEY2_DANRE", "id": "Q9I9L0-1", "name": "Hairy/enhancer-of-split related with YRPW motif protein 2", "aln": "-------------------------------------MKRPCEDSTSDS---------------DMDETIDVGSENNYSGQSNGSFIRCGSPTTTSQVMARKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQATGGKGY-FDAHSLAMDFLSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSSCASQREAAAMTTS-----------------------IAHHQQALHPHHWAAALHPIPAAFLQQSGLPSSESSSGRLS---EAPQRG-----AALFSHSDSALRAPSTG-----------SVAPCVPPLSTSLLSLSATVHAAAAAA--AAQTFPLSFPAGFPLFSPS-VTASSVASSTVSS---SVSTSTTSQQ-SSGSSSKPYRPWGTEVGAF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KM13-1", "uniprot_id": "HEY_DROME", "id": "Q7KM13-1", "name": "Hairy/enhancer-of-split related with YRPW motif protein", "aln": "MDHNMHVNAPSLHHWGYAAGPGVVMPGATATTPQSHWVPPPQSHHSAHSNHSHGHSQGHSHGIGSLKRTLSESDCDDLYSEESSKEQISPSEPGSCQLMSRKKRRGVIEKKRRDRINSSLTELKRLVPSAYEKQGSAKLEKAEILQLTVEHLKSLQSKTLDSLSYDPQRVAMDYHIIGFRECAAEVARYLVTIEGMDIQDPLRLRLMSHLQYFVQQRELSAKSCASPGGWSPAAPSSSGYQPNCAAAPYQSYAAPANPGAYVSSYPTLSASPSQQAQQLGGRTSVSRTSGSAVTESLPSHDLHSDSSSQQQQQQQQQQQQQQQHQQQQHQQQQQRTQTTPQPTQQQHYTHDHSAVHSEQQVPTYIELTNSNRPAAIGSDSLSYSAAPQYPVSGLPGQDYNNSSVLQYATPNGAKPYRPWGAEMAY-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .. ::.* .:..*:. .. :: .. .. * . :.*:*:******:***:******.**:**:****:*:***************:**:*** **:. .. :*.: :* *: ****** :****** ::**:* .****:**:***. . *** :. : : : . :* :.:: :.:: * ..:: * * . : :: :. : . .. ..: . : *:*. : .. : *: . . : .. : ::.. .. . . :: * :: .. ***:***:*:. ", "identical_positions": 97, "similar_positions": 117, "identity": "22.77%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000605-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63046-1", "uniprot_id": "RUNX1_RAT", "id": "Q63046-1", "name": "Runt-related transcription factor 1", "aln": "---------------------------------------------------------------------------------------------------------------------MRIP-----------------------------------------VDASTS-------------------------RRFTPPSTALSPGKMSEALPLGAPDG-GAALAS---------------------------------------------KLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRR------------------------HRQKLD----------DQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDARQIQPSPP-WSYDQSYQYLGSITSS-VHPATPISPGRASGMTSLSAELSSRLSTAPDLTAFGDP----------------------RQFPTLPSISD-----PRMHYP-GAFTYSP-PVTSGIGIGMS---------------------------AMSS-TSRYHTYLPPPYP-GSSQAQA-GPFQTG-------------------SPSYHLYYGTSAGSYQFSMVG------GERSPP--------------------------------RILPPCTNASTGAALLNPSLPSQSD-VVETEGSHSNSPTNMPP-----------------------------------------ARLEEAVWRPY------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03347-1", "uniprot_id": "RUNX1_MOUSE", "id": "Q03347-1", "name": "Runt-related transcription factor 1", "aln": "---------------------------------------------------------------------------------------------------------------------MRIP-----------------------------------------VDASTS-------------------------RRFTPPSTALSPGKMSEALPLGAPDG-GPALAS---------------------------------------------KLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRR------------------------HRQKLD----------DQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDARQIQPSPP-WSYDQSYQYLGSITSSSVHPATPISPGRASGMTSLSAELSSRLSTAPDLTAFGDP----------------------RQFPTLPSISD-----PRMHYP-GAFTYSP-PVTSGIGIGMS---------------------------AMSS-ASRYHTYLPPPYP-GSSQAQA-GPFQTG-------------------SPSYHLYYGASAGSYQFSMVG------GERSPP--------------------------------RILPPCTNASTGAALLNPSLPSQSD-VVETEGSHSNSPTNMPP-----------------------------------------ARLEEAVWRPY------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01196-1", "uniprot_id": "RUNX1_HUMAN", "id": "Q01196-1", "name": "Runt-related transcription factor 1", "aln": "---------------------------------------------------------------------------------------------------------------------MRIP-----------------------------------------VDASTS-------------------------RRFTPPSTALSPGKMSEALPLGAPDA-GAALAG---------------------------------------------KLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRR------------------------HRQKLD----------DQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPP-WSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDP----------------------RQFPALPSISD-----PRMHYP-GAFTYSPTPVTSGIGIGMS---------------------------AMGS-ATRYHTYLPPPYP-GSSQAQG-GPFQAS-------------------SPSYHLYYGASAGSYQFSMVG------GERSPP--------------------------------RILPPCTNASTGSALLNPSLPNQSD-VVEAEGSHSNSPTNMAPS----------------------------------------ARLEEAVWRPY------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JET8-1", "uniprot_id": "A0AC58JET8_DANRE", "id": "A0AC58JET8-1", "name": "Runt-related transcription factor", "aln": "--------------------------------------------------------------------------------------------------------------------MHRVPGQNRLAGPTQADRGVPAVGQIREPFKIREQIKLEALDSDEDVDKQTLPMASNSIFESFQSYQSCFSREPAPGRRFTPPSTTLSSGKMSEGLPLGAQESTGAALVG---------------------------------------------KLRMADRSMVEVLSDHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDIPDGTLVTVMAGNDENYSAELRNATAAIKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYQRAIKITVDGPREPRR------------------------HRQKPD----------EAVKPGALAFSE------QLRRSAMRCSPHH-GPAPNTRPTLN-TPPFGSPAHSQIPDSRQMQTSPS-WSYEQSYPYLGPISTPAVHPTTPISPNRTA-------------LHCPELTAFTDPR-----------------VGLERSFPSLPSLPDGRFSDPRVPYPTGAFTYTPTPVTSAIGIGMS---------------------------AMSSPAGRYHTYLPPAYPAGSSQAQA-GAFQAS-------------------SSPYHLYYSSAAGSYQFSMMPSGGAAAGERSPP--------------------------------RILP-CTNASTGSALLHPSLPNQSEGVVEAEGSHSSSPTSMSV---------------------------------------------EAVWRPY------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W349-1", "uniprot_id": "LOZEN_DROME", "id": "Q9W349-1", "name": "Protein lozenge", "aln": "MHLHLLAAEKTPPSPSPNPTPTPSASPSGHTGAAGESQLDLASQTESQLQLGLPLASGYGLGLGLGLGLGLGLGQELVADHSTTVAPVSVAGPGRLGRSINGSGGSHHHHH----LHHHYSPYHHAHPYHPPHPHAPHHHHHHHPPYPYPPAGPHPPAMVTSSSTSPTGNGWSSSTGDFKGITAVATATGGGVGGATQGATASTGATAAEVLAVSSSASVGSSSPTGGASNGTAHSGHSGHTGGHSSSTASNNNNNGASNSNSNNNNAVHQDLLWMERLVQKRQQEHPGELVRTSNPYFLCSALPAHWRSNKTLPMAFKVVALAEVGDGTYVTIRAGNDENCCAELRNFTTQMKNDVAKFNDLRFVGRSGRGKSFTLTITVATSPPQVATYAKAIKVTVDGPREPRS------------------------KTSPTGGPHYRALGLGQRPYIDGFPSTKALHELESLRRSAKVAAVTTAAAAAATAASAANAVAAAAAAVAVTPTGGGGGVAAGGVAGGAGAGLVQQLSSNYSSPNSTINSDCQVYKPNAPHIQAAEMMGAGEWTNGSSS-------------------SAAAYYHSHAHHPHAHHAHAHLQHQMALPPPPPPPAAAPVSVGVGGNGATMGMGMGVGVGMGMNHYGGGYDSANSLEAGQYAAHLPAVLPEMHGHGFATDPYQTAGYGGGNTGGGSASKSELDYGGSYNQAWSNGYQNYQYGSCLATAQYGPQAAPPPQPPPPPPVVLCPQLYSTVNQNQIHLHLHSSEKLEQYLGTATSADHLTIGSLTGSSRSSIEIGQDQYHQQVHHAQQQQQQQQQQQQVHHPQQQQVESAGEVGGSGAGGVESAREEDVGDLSQVWRPY------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PI08-1", "uniprot_id": "M9PI08_DROME", "id": "M9PI08-1", "name": "", "aln": "-------------------------------------------------------------------------------MHLTTTSSNSTASNANNNNNNTANNNNTSSNNNTTNTNG-------------------------------------------SSNNNTS--------------------------GNNNNSSGNNSNTEQNTPPTPAQLLNEAYTKMT--------------------------------------------SDILAERTLGDFLTEHPGELIRTSSPLFVCTVLPPHWRSNKTLPVAFKVVSLGDIMDGTMVTVRAGNDENYCAELRNCTAVMKNQVAKFNDLRFVGRSGRGKSFTLTITVSTNPPHIATYNKAIKVTVDGPREPRSKTMLSLLGQQQQFHFAFGQRPFHFSTDPLSGFRMPPIGNCQSASNTHWGYGSAASAYSPYLASSGLSSCTTPTSAQFNNPALGFTCSSNDQSNNQDFGGATNRDCVPMLPDSTASDLDQHLSSLVGSTSGQMTHHSLLGAGGQTSISSTVNGASGGGSAGAGTAGGGAGSGGGAGGGAGGNSILVPRYHTNASNEYNVHSSQNGPRSLSDSSQAESPVQEDLLTTNTPN-------------LGSTAGGGAANGGAGSNAGSGAAGSGAGGAGGASSAVGNPAMLGAN---------------QNFPGIVNQAQHSAASAYGGGTGVVGGGHGSAAAAAAGCNGSLYPVLPASLLYSQLYTAANQSAHG--FHSHTLPAHASPNSSVHGELQSVMDHISNVGVRQQHNIMAGGGVTHPGDLTLIGNCGASVRNIEDGNSNRQVAALAAHRGHHNPTDNGGSVWRPYXGQVLWCGSAVL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VRA9-1", "uniprot_id": "Q9VRA9_DROME", "id": "Q9VRA9-1", "name": "", "aln": "-------------------------------------------------------------------------------MHISAEVSSTTSNQIQQQQQQHQQQQQHQLLQHQQQQTATTTTTKRRNAESSASSN-------------------------NNNNNNTSTTNNNN-------------------TNNNNNSTTNNNNNNNNNNVKTKPVDTSPYLTP----------------------------------------------ENLIERTVDVLLAEHPGELVKTGSPHVVCTTLPTHWRSNKTLPIAFKVLALGEVMDGTIVTIRAGNDENFCGELRNCTAVMKNQVAKFNDLRFVGRSGRGKSFTLTIVISTNPIQIATYTKAIKVTVDGPREPRSKVRHQG------------FHPFAFGPQRFGPDPLMAGLPFKLPGFAHHLVGMHSHLHAPDWRAHMALGGRPAAFTAAPFFGHHAAAFPTASGLRGLSGDSQQHQQQQQQHQLATVGAAHSTTSPEGSPTTTTTSGTQLSAFVQPPMTSSPPPVTSLQHDNNNNNSNNNNSSSHIDAGFESDSISVTGSPRKSLGSPLTHDEEEAEAEAEAEAEAEAEAEEAEVGGLSRNGGGIQG----PLHSESSPGSGGAFTALIQRSGKNPTELFGGFAAAGGNHFAPSGHSFNP---------ALAAQLFLQSPLLPQSSQWLYTQLYGSYSDLPWLRNAAAAAAANINPGQENSGIPPLGSNPDHDGVNLIKRCVTLITHNPPDAENANPNASPPVSSTRRSPSPVETIDLDDVSTTSRSASGS----------------SGHGGGVGGGGAVGPIRTRTPKPSADVWRPY------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. . :: . . : . :* : :*****::*..* .:*:.**.***.*****:****::*.:: *** **: ****** ..**** *: :**:**:********************.: *.* ::*** :***:********* . . . : . : : :: . . . . . . . . . : : . . . . :.. . : . . . ***** ", "identical_positions": 86, "similar_positions": 75, "identity": "9.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000607-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9HCL0-1", "uniprot_id": "PCD18_HUMAN", "id": "Q9HCL0-1", "name": "Protocadherin-18", "aln": "MHQMN-AKMHFRFVFALLIVSFNHDVLGKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRGNSPLLVVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHVTRIRAIDRDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKVLLKCMIFEYAESVTSTAMTS--VSQASLDVSMIIIISLGAICAVLLVIMVLFATRCNREKKDTRSYNCRVAESTYQHHPKRPSRQIHKGDITLVPTINGTLPIRSHHRSSPSSSPTLERGQMGSRQSHNSHQSLNSLVTISSNHVPENFSLELTHATPAVEQVSQLLSMLHQGQYQPRPSFRGNKYSRSYRYALQDMDKFSLKDSGRGDSEAGDSDYDLGRDSPIDRLLGEGFSDLFLTDGR---IPAAMRLCTEECRVLGHSDQCWMPPLPSPSSDYRSNMFIPGEEFPTQPQQQHPHQSLEDDAQPADSGEKKKSFSTFGKDSPNDEDTGDTSTSSLLSEMSSVFQRLLPPSLDTYSECSEVD----RSNSLERRKGPLPAKTVG----YPQGVAAWAASTHFQNP--TTNCGPPLGTHSSVQPSSKWLPAMEEIPENYEEDDFDNVLN----HLNDGKHELMDASELVAEINKLLQDVRQS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VHR0-1", "uniprot_id": "PCD18_MOUSE", "id": "Q8VHR0-1", "name": "Protocadherin 18", "aln": "MHQMN-TKMHFRFALALLMAFFSHDVLAKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSAVRFRAMPRGNSPLLVVNENTGEISIGAKIDREQLCQKNLNCSIEFDVLTLPTEHLQLFHIEVDVLDINDNSPQFSRPVIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDYFNIEVRTRTDGAKYAELIVVKELDRELKASYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQPSYTIQLLENSPVGTLLLDLNATDPDEGANGRIVYSFSSHVSPKIIETFKIDSEKGHLTLFKPVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEISINLMSPGKEEVSYVFEGDPIDTFVAIVRVQDKDSGLNGEIICKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYSLTVIAEDKGTPSLSSVRHFTVQINDINDNPPRFQRSRYEFVISENNSPGAYITTVTATDPDLGENGHVTYTILESFVLGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSQKQLSSNTTVVLTIIDENDNVPVVIGPAMHNNTAEISIPKGAESGFHVTRIRVVDRDSGANAEFSCSIVSGNEENIFIMDPRSCDIHTNVSMESIPSAEWALSVIIQDKGSPPLHTKVLLRCMVFDYAESVTSTAMTS--VSRASLDVSMIIIISLGAICAVLLVIMVLFATRCNREKKDTRSYNCRVAESTYQHHPKRPSRQIHKGDITLVPTINGTLPIRSHHRSSPSSSPTLERGQMGSRQSHNSHQSLNSLVTISSNHVPENFSLELTHATPAVE-VSQLLSMLHQGQYQPRPSFRGNKYSRSYRYALQDMDKFSLKDSGRGDSEAGDSDYDLGRDSPIDRLLGEGFSDLFLTDGR---IPAAMRLCTEECRVLGHSDQCWMPPLPSPSSDYRSNMFIPGEEFPAQPQQQHSHQGLDDDSQPAENGEKKKSFSTFGKDSPSDEDSGDSSTSSLLSEMSSVFQRLLPASLDTFSECNEGD----RSNSLERRKGPAQGKTGG----YPQGVAAWAASTHFQNP--TSSSGTPLGTHSSVQPSSKWLPAMEEIPENYEEDDFDNVLN----HLSDGKHELMDASELVAEINKLLQDVRQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QRP2-1", "uniprot_id": "F1QRP2_DANRE", "id": "F1QRP2-1", "name": "", "aln": "METSKGTVLCATLLKLALLVTLAGYTTAATLKYQVYEEQKVGTVIARLREDVADVLSKLPSSIPLRFRAMQRGSASLLSVRDQDGEISIRTKIDREKLCEKNLNCTIEFDVLTLPTEHLQLFHIEVEILDINDNAPQFARPVIPIEISETAAVGTRIPLDSATDPDVGENSLNTYSLTPSDFFKIDILTRTDGAKYAELVVLKELDREVRASYELQLTASDRGVPPKFGTTLLKISIADSNDNNPVFEKPSYVINLLENSPLGSLLIDLNATDPDEGANGKIIYSFSSHVSPKILETFKINSDNGHLTLMRKVDFESTNSYDIDVQAQDMGPNSMPAHCKVIIKVVDVNDNKPDISVNLMSTGNEEIAYISETAPVDTFVALVSVNDLDSGLNGEVECRLYGQGHFRLQKSYEKNYMILTNVTLDREKRSEFSLTVIAEDKGSPSLSTIKNFIVEVQDENDNAPSFAKSRYEISKAENNSPGAYLSSVKASDPDLGPNGQVSYSILESMVHGSSISTYVTIDPSNGDIYALRTFDREDVSQISFLVQARDSGNP-PLRSNVTVVLTVLDENDNRPVIMMPQLWNHTADVPVSKYAEIGDVVTVVRAMDHDAGANGDLSCSVVGGNEAGYFNMDPKTCEIRTNVSIQEVPRDHVELTILVQDHGTPTLSARALLRLSLYENIENLMNPHLTGGRNGDGPLDVSMIIIISLGAICAVLLLIMVAFALRCSREKKDTRSYNCRVAESTYQQHPKKPSRQIHKGDITLMPTVNGTLPIRAHHR-SPTSSPGPERAHMGSRQSQHSRQSLNSLVTISSNHIPENFALELTHATPPVEQVSQLLSILHQGQYQPRPSFRGNKYSRSYRYALQDMDKFSLKDSGRGDSDAGDSDCEMGRDSPIDRLLGDGFGDLFHSDGHHRLHPAVMRLCTEECRVLGHSDQCWMP--SQASSDYRANMFIPGEESRPQ--------VLEEDQQSVDS--AKKSFSTFGKD--NEEECG----GSLLSEMNNVFQRLLPTSYADVRELDESTSQPASSIGMEIRKGFLPGKASSTGSAYPQGVAVWAANTHFQNPGGAVTSGHATTNHAASQAHLKWLPAMEEIPENYEEDDLESVLSQRQGKRNDTRHEVVDASELVAEINKLLQDVRQS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : : : : *:. : . . .***::****:**:***** ******* ***.. .:***** **.:.** *.:: ***** :.****:**:*****:*****:**************::******:***:*.:*******:************ *********:****:..*:*:*:: ***********:*::*****:::********** *** : *:::*****:*****.*.**: ** *:******:*:**:*************:*:***********:*****:*:.*****:: **:* *:**:*******:****:*****:************:*.:****.*:**::*: * *:*****:* *:* *******: *:*:*:***:***:**:**:****.*********:********:*:****::::* *:::* ***.* * :****: :********:::*.*:***** **:*:*:****:: ****:********** ***** **:*:****:*:*:***.*. * **.*****::***** **:: * : *:**::.:.* ** * ** :*.:*:*:*.*.::**::*.*** . * :**::*:*:****::.:* . *::::**:*.* * ::.**: ::: *.: .. :*. . ..*******************:*** ** **.*******************:***:************:**:*******:*** **:*** **.:******::*:*************:****:********.** ******:*****************************************:***** ::***********:**.*** :**: **.******************** ...*****:******** .* *::* *..:. ********** .:*: * .******..*******.* * .* * .:* *** .*: . ******.***.****** : ..* . .*:: *. *****************::.**. : .* :**::*******************", "identical_positions": 745, "similar_positions": 255, "identity": "64.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000607-13", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M8W4-1", "uniprot_id": "SOX5_RAT", "id": "F1M8W4-1", "name": "Transcription factor SOX-5", "aln": "MLTDPDLPQEFERMSSKRPASPYGETDGEVAMVTSRQKVEEEESERLPAFHLPLHVSFPNKPHSEEFQPVSLLTQEACGPRTPAAQHSTMEVDGNK--VMSSLAPYNSSTSPQKAEEGG---RQSGESVSSAALGTPERRKGSLADVVDTLKQRKMEELIKNEPEDTPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQ-VQGQLPPLMIPVFPPDQRTLAAAA-QQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQFYAAQLAAMQVSPGGKLLGLPQGNLG-AAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPASPTSPHMPALRINSGAGPLKASVPAALASPSARVS---------TIGYLNDHDAVTKAIQEARQMKEQLRREQQALDGKVAVVNSIGISNCRTEK----EKTTLESLTQQLAVKQNEEGKFSHGMMDFNMSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDINGEIYEEYEEEEEDPDVDYGSDSENHIAGQAN---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35710-1", "uniprot_id": "SOX5_MOUSE", "id": "P35710-1", "name": "Transcription factor SOX-5", "aln": "MLTDPDLPQEFERMSSKRPASPYGETDGEVAMVTSRQKVEEEESERLPAFHLPLHVSFPNKPHSEEFQPVSLLTQETCGPRTPTVQHNTMEVDGNK--VMSSLSPYNSSTSPQKAEEGG---RQSGESVSSAALGTPERRKGSLADVVDTLKQRKMEELIKNEPEDTPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQ-VQGQLPPLMIPVFPPDQRTLAAAA-QQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQFYAAQLAAMQVSPGGKLLGLPQGNLG-AAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPASPTSPHMPALRINSGAGPLKASVPAALASPSARVS---------TIGYLNDHDAVTKAIQEARQMKEQLRREQQALDGKVAVVNSIGLSNCRTEK----EKTTLESLTQQLAVKQNEEGKFSHGMMDFNMSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATAGVVYPSAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGAKGEEPHIKEEIQAEDINGEIYEEYDEEEEDPDVDYGSDSENHIAGQAN---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35711-1", "uniprot_id": "SOX5_HUMAN", "id": "P35711-1", "name": "Transcription factor SOX-5", "aln": "MLTDPDLPQEFERMSSKRPASPYGEADGEVAMVTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQPVSLLTQETCGHRTPTSQHNTMEVDGNK--VMSSFAPHNSSTSPQKAEEGG---RQSGESLSSTALGTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQ-VQGQLPPLMIPVFPPDQRTLAAAA-QQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGIPQGNLG-AAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPTSPTSPHMPALRINSGAGPLKASVPAALASPSARVS---------TIGYLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCRTEK----EKTTLESLTQQLAVKQNEEGKFSHAMMDFNLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDINGEIYDEYDEEEDDPDVDYGSDSENHIAGQAN---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q0N4-1", "uniprot_id": "A0A8M9Q0N4_DANRE", "id": "A0A8M9Q0N4-1", "name": "", "aln": "MLTEPELPQEFNRMSSKRPASPYGGTDGEVVMATSRQRLEDEEVDGHAVIHLPLSS------YCSKVSPRSPRLLD-----SPPTLHANMDQDGSKGLALSPYAQHNSSTSPSKQQQEDSSMRPGSEPGSASALGTPERRKGSLADVVDTLKQRKMEELIKNEPEEAPSIERLLSKDWKDKLLAMGSGNFGEIKGTPDSLAEKERQLMGMITQLSSLREQLLAAHEEQKKLAASQIEKQRQQMELAKQQQDQIARQQQQLLQQQHKINLLQQQIQQVQGQLPPLMIPVFPPDQRTLAAAAAQQGFLLPPGFNYKPGCSEPYPLQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGAKHSTVPQANLATGTLSPTSGQSEKNRSTPPPKPKDEGAQPLNLSSKPKASESKSPTSPASPQVPALKLGPGS--LKHSAPSSIGGPPSRLSSIDLLSSITSAGYLNDHEAVTKAFQEARKMKEQLKREEQVLDAKVAAVNSLSLNNGRSEKVRFMEKAALESLSQQL--KQSEESKFTHAMMDFGISGDSDGSPSVSDSRIFREARGRGSSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFTVGQQAQLPLSSAGVVYPGALSMAGMPSPQMPSEHSSMSSSPEPVPPTSQASY-FKEVEPRVKEELRMDDGNGDAYDDFDYEDDDG--DYGSDSENHITQ------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q59DN5-1", "uniprot_id": "Q59DN5_DROME", "id": "Q59DN5-1", "name": "", "aln": "-------------MKPPGEDQTNEKEHSDLGMIKQLQLIRNRILS--------------------------------------QAHYDSMT---------------DIDASAQQQQQLQNVQRLQHESCLQELHNHLSSQYGAVRFTAANPQHQNQQAVSVSSGNLMPFLPAFLQPPMPN-----AQQLLQLIPGHENAQSVPTHHHSHPQSEAFSTHKMALAPMWSTAAVAAAHIQAALAAAAVAAANNN---KNSSHFSNNTNIVGLATRGNELLNTDSDPQMEIGETRRGGNGGSCR-----SRPESPTYEN-----PPYEILSYSHNTPPESPHGR----------------TADCSKNFSPSPTDNLSIASVSEAQ--------------DSEMDAPLNLS-KPKGSPSSSPNSSSQRDH-----------CENLTPVVSSPPLSWHQG--------QPHYAEIELPLLKSHGRVWNSAVACSGGSRATRVSRDSVNSCGTNSERSAA--------------------LDPESLNSGQLGPVPASPSSQPLRQGNGHGHGGNHGHVHSKPHIKRPMNAFMVWAKDERRKILKACPDMHNSNISKILGARWKAMSNADKQPYYEEQSRLSKLHMEQHPDYRYRPRPKRTCIVDGKKMRISEYKVLMRNRRAEMRQLWCR----------TGGVSGGSGSLCADACP-----KGSGGSNSQVAVAAAAAVYHLQDMASSAASTAHGHDCGHTPPQQFFYPPESLSPSGFSSDEVELASQRELDD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. .. ..:: * .. * :.:. . : .* : .:*..: :: * *. . . : *:: .. . :::: : : .. : * : :*. : .. : * * :: : :: .: * :: **. . :**::*: :* ::: ::..:: :: : :.* : : :: : * * . . .:. * . .*: * :::. : :.. :. * .. . : * **. .::* :. ..* ***** *** * ..** *.:. . : .* . * : . * : . .: *: .. : .:. . *** . .. *: : .:. . :. :. *. . .:.: . :*: .:**********************:* *************:***:*:* :********:**** *:*::***:*:*******:*****:**.***.:***** **** : :* * .: ::.. ..* :.* .*..: .. : * : . . : .* . ::: :. . *..* .:: ", "identical_positions": 147, "similar_positions": 214, "identity": "18.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000607-16", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M5B7-1", "uniprot_id": "A0ABK0M5B7_RAT", "id": "A0ABK0M5B7-1", "name": "B-cell CLL/lymphoma 7 protein family member A", "aln": "MSGRSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLRIYKWVPVTEPKVDDKNKNKKKGKDEKCGSEVTTPENSSSPGMMDMHDDNSNQSSIADASPIKQENSSNSSPAPEPNAPVPSDGTEAKADEAQAEGKEHPGAEDASDEQNSQSSMENSTNSSEKAERQPSAESGLAAETSAISQDLEG-VPPSKKMKLEASQQNSEEM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CXE2-1", "uniprot_id": "BCL7A_MOUSE", "id": "Q9CXE2-1", "name": "B-cell CLL/lymphoma 7 protein family member A", "aln": "MSGRSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLRIYKWVPVTEPKVDDKNKNKKKGKDEKCGSEVTTPENSSSPGMMDMHDDNSNQSSIADASPIKQENSSNSSPAPETNPPVPSDGTEAKADEAQADGKEHPGAEDASEEQNSQSSMENSVNSSEKAERQPSAESGLAAETSAVSQDLEG-VPPSKKMKLEASQQNSEEM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4VC05-1", "uniprot_id": "BCL7A_HUMAN", "id": "Q4VC05-1", "name": "B-cell CLL/lymphoma 7 protein family member A", "aln": "MSGRSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLRIYKWVPVTEPKVDDKNKNKKKGKDEKCGSEVTTPENSSSPGMMDMHDDNSNQSSIADASPIKQENSSNSSPAPEPNSAVPSDGTEAKVDEAQADGKEHPGAEDASDEQNSQSSMEHSMNSSEKVDRQPSGDSGLAAETSAISQDLEG-VPPSKKMKLEASQQNSEEM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XFY4-1", "uniprot_id": "BCL7A_DANRE", "id": "Q5XFY4-1", "name": "B-cell CLL/lymphoma 7 protein family member A", "aln": "MSGRSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLRIYKWVPVTEPKSDD-NKNKKKGKDDKYGSEVTTPENSSSPGMMDMHDDNSNQSSIADSSPLKQETSNNTSPAPEPMAASQNDSSDLKNDQYPS--KQPSSGQDHKSEQN-HCSSE-SMTS--KRDSKSQGDSESFLDSSKSAQELEDGAPPSKKGKIDSSSEES---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O76857-1", "uniprot_id": "O76857_DROME", "id": "O76857-1", "name": "", "aln": "-MSRSVRAETRSRAKDDIKRVMQAVDKVRHWEKKWVTISDTTMKIYKWVPIAS-------ASEKKAKLESSPGSAAVRRPPPGSGVTPVGGSKSDK-----------ENSQKGTPTPPQITPSYQGLTAEDSNTCFSVVSDSQGADFVS---------------------------SMPFSEDSNSQGSDG---PVKRLKTSD--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .******************* *::***:*******:.**:::******::. .:**.* :. ...:. . ....*: : ..:*:: *.*.: :*:* .. .. : . : : .: ..: . . . :* :. * *: * . ", "identical_positions": 51, "similar_positions": 60, "identity": "24.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000607-21", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGK6-1", "uniprot_id": "YLAT2_MOUSE", "id": "Q8BGK6-1", "name": "Y+L amino acid transporter 2", "aln": "-------------MEAQELGSPTPT---YHLLPKANQHTVKEDAGSPSQGSPE--TMQLK---KEISLLNGVSLVVGNMIGSGIFVSPKGVLKYTASYGLS-LIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLIVEPTSQAIIAITFANYIIKPSFPTCDPPYVACRLLAAACVCLLTFVNCAYVKWGTRVQDTFTYAKVLALIAIIIMGLVKLCQG-----HTEHFQDAFKGSSWNVGD--LSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNIQDVHKS-DAVAVTFADQTFG--MFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPNLLSMIHIERFTPVPALLFN-----CTMTLIYLVVKDVFLLIN-YFSFSYWFFVGLSVVGQLYLRWKEP----DWPRPLKLSLFFPIVFCVCSLFLVAVPLFSDT------------INSLIGIGIALSGVPVYFLGVYLPESR--RPLFIRNVLATVTRVTQKLCFCVLTELDVTEEKNVERKTD--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZMM8-1", "uniprot_id": "YLAT2_RAT", "id": "D3ZMM8-1", "name": "Y+L amino acid transporter 2", "aln": "-------------MEARELGSPTPT---YHLLPKANQHTVKEDASSPSQGSPE--TMQLK---KEISLLNGVSLVVGNMIGSGIFVSPKGVLKYTASYGLS-LVVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLIVEPTSQAIIAITFANYIIKPSFPTCDPPYVACRLLAAACVCLLTFVNCAYVKWGTRVQDTFTYAKVLALIAIIIMGLVKLCQG-----HTEHFQDAFKGSSWNVGD--LSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNIQDVHKS-DAVAVTFADQTFG--MFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPNLLSMIHIERFTPVPALLFN-----CTMTLIYLVVKDVFLLIN-YFSFSYWFFVGLSVVGQLYLRWKEP----DWPRPLKLSLFFPIVFCICSLFLVAVPLFSDT------------INSLIGIGIALSGVPVYFMGVYLPEAR--RPLFIRKVLATVTRVTQKLCFCVLTELDVAEEKNVERKTD--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92536-1", "uniprot_id": "YLAT2_HUMAN", "id": "Q92536-1", "name": "Y+L amino acid transporter 2", "aln": "-------------MEAREPGRPTPT---YHLVPNTSQSQVEEDVSSPPQRSSE--TMQLK---KEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMS-LIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQG-----HSEHFQDAFEGSSWDMGN--LSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSS-DAVAVTFADQTFG--MFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFN-----CTMALIYLIVEDVFQLIN-YFSFSYWFFVGLSVVGQLYLRWKEP----KRPRPLKLSVFFPIVFCICSVFLVIVPLFTDT------------INSLIGIGIALSGVPFYFMGVYLPESR--RPLFIRNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q59I64-1", "uniprot_id": "YLAT2_DANRE", "id": "Q59I64-1", "name": "Y+L amino acid transporter 2", "aln": "--------------------------------------------------------MQLK---KEISLLNGVSLIVGNMIGSGIFVSPKGVLIYSASYGLS-LVIWAIGGIFSVVGALCYAELGTTITKSGASYAYILESFGGFIAFIRLWTSLLIIEPTSQAVIAITFANYLVQPLFPTCEPPYSASRLIAAACICLLTFINSAYVKWGTRVQDVFTYAKVLALIVIIITGIVKLCQG-----FTINFEDSFQGSSRDPGG--IALALYSALFSYSGWDTLNFVTEEIKNPERNLPLSIAISMPIVTIIYILTNVAYYAVLDMSAILAS-DAVAVTFADHTLG--VMSWTIPIAVALSCYGGLNSSIIAASRLFFVGAREGHLPDALSMIHIERFTPVPALLFN-----CAMALIYLTVEDVFQLIN-YYSFSYWFFVGLSIAGQIYLRWKEP----DRPRPLKLSLVYPIIFCLCVVFLVAVPLYSDT------------LNTLIGIAIALSGVPVYFLGIHLPESK--RPPIITKLLSAITRFTQFTCFYVLTEMDTVD-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHK8-1", "uniprot_id": "A0A0B4KHK8_DROME", "id": "A0A0B4KHK8-1", "name": "Y+L amino acid transporter 2", "aln": "-------------METESLNRKNSSRK-SSIVNGNGDASAKLTNGDGDGGGDGGGEVTLK---AKMSLLNGCTVIVGSIIGSGIFVSPTGVLMYTGSVNLA-LIVWVISGLFSMVGAYCYAELGTMITKSGADYAYIMETFGPFMAFIRLWIECMIVRPCSQAIVALTFSTYVLKPFFPECTPPEDSARLLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIATGVYQLYLG-----NTQYFT--FENTDTKVTS--IALSFYSGLFAYNGWNYLNFIIEELKDPVKNLPRAIAISCTLVTIVYVMANVSFYTILSPDEVMGS-SAVAVTYAERAFG--MLAWTIPVFVALSTFGAVNGILLTSSRLFYAGANNGQMPEILTMIQIQRFTPTPAVLAM-----ALLSMLYLTVSDIFALIN-YVGFATWLSIGVAVLCLPWLRWAQP----NLPRPIRVPMVFPIVYLIATIFVTVVPMYASP------------VETGYGILMILSSIPVYLV--FIAWKN--KPIWFQKTMVSLTRFLQKMLMVLGKQTKPAQV----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50276-1", "uniprot_id": "MUP1_YEAST", "id": "P50276-1", "name": "High-affinity methionine permease", "aln": "-----MSEGRTFLSQLNVFNKENYQFSSSTTKKEVSNSTVDADNGASDFEAGQQFATELDQGEKQLGILSCIGLICNRMLGTGVFAVSSTIYTLCGSVGLA-LIMWAVGAIIAISGLYVYMEFGTAIPKNGGEKNYLEAIFRKPKFFITCMYAAYIFFLGWAAGNSINTAIMFLTAADTEVTKWNQ--RGIGVAVVFFAFLINSLNVKIGLYLQNILGIFKIGIVLFISITGWVALGGGLKDGYQSHNFRNAFEGTETATAYG-IVNALYSVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSMVFLAIIYIFVNIAYFAVVPKDKLISSKLILAADFFDIVFGG-QAKRAAAALVGLSALGNVLSVIFSQGRIIQQLGREGVLPFSNFFASSKPFNSPMVGLFQH-FIVCTVTILAPPPGDAYLLVQNLISYPMNIINFAISAGLLWIYWQRRQGKIEWNPPIKAGVFVTGFFTLSNLYLIIAPYVPPSNGESVYSSMPYWIHCVIAWGIFFFGGVYYVVWAQLLPRWGHYKLVSKDVLGEDGFWRVKIAKVYDDTIGDVDTQEDGVIETNIIEHYKSEQEKSL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38734-1", "uniprot_id": "MUP3_YEAST", "id": "P38734-1", "name": "Low-affinity methionine permease", "aln": "MEPLLFNSGKANPSQDVFIDVEVGDITTKYGSTNTGSFSSMDTVEAQAIKAETARFMEVPQG-RHLGVFSTVVLFVSRIMGSGIFAVPSVILLNTGGNKLIYFAIWVFSAAIAFAGLYLFLEFGSWIPKSGGRKNFLERSFERPRLLISVVFSCYSVLTGYALTGSIVFGKYVLSAFG---VTDDSWSKYVSISFIIFAVLIHGVSVRHGVFIQNALGGLKLIMIVLMCFAGLYTLFFYKSTGQVAWDLPVTQVEKDSLLSVSSIATAFISSFFCFSGWDTVHTVTSEIKNPVKTLKVSGPLSLIICFVCYTMMNVAYLKVLTYEEIVSAGPLVGSVLFTKLFGPRVGGKFIAFSIAISAASNILVVIYSISRVNQEIFKEGYLPFSIHMSKNWPFDAPLPSISLCGFITIAWILILPKEGESFNYLVSMDGYGNQFFLLLVAIGLFIWRFKHK----NEVPEIRASTFGVLAIITLSLYMLMAPFFADPSLN--------RVGFLPPYQIMSLLVIVACFFFWLVKFVLLPKFFHYKLLPKITYLHDGLIVTEWVKKPCLC-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:.::. :. . ::*:*:*. .. : .. : : :*.... ::. * : *:*: *.*.*. :: * :* . :: . .: . : :. . : . ::: *: . :*: : *: :. : * * : : .. : :: * ::.: *:. :: *:*:* :.* : * : : * : *::: :: . : : :. :* . :.:* . : : : .*: .:* :* : * . : :: : : : .: : : . . :: . ::: .* . . : : . : . : ", "identical_positions": 33, "similar_positions": 140, "identity": "5.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000607-49", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88923-7", "uniprot_id": "AGRL2_RAT", "id": "O88923-7", "name": "Adhesion G protein-coupled receptor L2", "aln": "--MVSSGCRMRS----------LWFIMIISFSPNTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTDCYLPDAFKIMTQRCNNRTQCVVVTGSDVFPDPCPGTYKYLEVQYECVPYMEQKVFVCPGTLKAIVDSPSIYEAEQKAGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNSRQTTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETTYDKRAASNAFMICGVLYVVRSVYQDNESEAGKNVIDYIYNTRLSRGEHVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELFKTTVSTTSSTSQRGPVSSTVAGPQEGSRGTKPPPAVSTTKIPPVTNIFPLPERFCEALEMKGIKWPQTQRGMMVERPCPKGTRGTASYLCMASTGTWNPKGPDLSNCTSHWVNQLAQKIRSGEN-AASLANELAKHTKG-TVFAGDVSSSVRLMEQLVDILDAQLQELKPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRAETLDCWKHMNSSEQAHTATMLLDTLEEGAFVLADNLLEPTRVSMPTDNIVLEVAVLSTEGQVQDFTFHLG--FKGAFSSIQLSANTVKQNSRNGLAKVVFIIYRSLGPFLSTENATVKLG-ADLLGRNSTIAVN-----------------SHVLSVSINKESSRVYLTDPVLFSMPHIDSDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIVYKDGVHKLL--LTVITWVGIVVSLVCLAICIFTFCFFRG--LQSDRNTIHKNLCINLFIAEFIFLIGIDKTQYTIACPVFAGLLHFFFLAAFSWMCLEGVQLYLMLV----EVFESEYSRKKYYYVAGYLFPATVVGVSAAIDSKSYGTLEACWLHVDNYFIWS-FIGPVTFIILLNIIFLVITLCKMVKHSNTLKPDSSRLENINNYRVCDGYYNTDLPGYEDNKPFIKSWVLGAFALLCLLGLTWSFGLLFVN------EETVVMAYLFTAFNAFQGLFIFIFHCALQKKVRKEYAKCFR------HWYCCGGLPTESPHSSVKASTSRTSARYSSGTQSRIRR---------------------------------MWNDTVRKQSESSFISGDINSTSTLNQG-------------------------------------------------MTGNYLLTNPLLRPHGTNNPYNTLLAETVVCNAPS-----------------------------------------------------------------APVFNSPG-------------------------------------------HSLNNTRDTSAMDTLPLNGNFNNSYSLRKADYHDGVQVVDCGLSLNDTAFEKMIIS-----------------------------ELVHNNLRGSNKTHNLELKLPVKPVIGGSSSEDDAIVADASSLMHG------DNPGLEFRH-------------KELEAPLIPQRTHSLLYQPQKKVKPEATD----SYVSQLTAEADEHLQSPNRDSLYTSMPNLRDSPYPESSPDMAEDLSP------------------SRRSENEDIYYKSMPNLGAGRQLQMCYQISRGNSDGYIIPINKEGCIPEGDVREGQMQLVTSL----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JZZ7-1", "uniprot_id": "AGRL2_MOUSE", "id": "Q8JZZ7-1", "name": "Adhesion G protein-coupled receptor L2", "aln": "--MVSSGCRMRS----------LWFIIIISFSPSTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTDCYLPDAFKIMTQRCNNRTQCIVVTGSDVFPDPCPGTYKYLEVQYECVPYSKMLVFVCPGTLKAIVDSPCIYEAEQKSGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNSRQTTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETAYDKRAASNAFMICGVLYVVRSVYQDNESEAGKNTIDYIYNTRLSRGEYVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELFKTTISTTSSASQRGPVSSTAAGPQDGSRGTKPPPAVSTTKIPPVTNIFPLPERFCEALDWKGIKWPQTQRGMMVERPCPKGTRGTASYLCMASTGTWNPKGPDLSNCTSHWVNQLAQKIRSGEN-AASLANELAKHTKG-HVFAGDVSSSVRLMEQLVDILDAQLQELKPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRAEALESWKHMNSSEQAHTATMLLDTLEEGAFVLADNLLEPTRVSMPTENIVLEVAVLSTEGQVQDFKFPLG--LKGLGSSIQLSANTVKQNSRNGLAKLVFIIYRSLGQFLSTENATIKLG-ADLMGRNSTIAVN-----------------SPVISVSINKESSRVYLTDPVLFTLPHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDGVHHLL--LTVITWVGIVVSLVCLAICIFTFCFFRG--LQSDRNTIHKNLCINLFIAEFIFLIGIDKTKYTIACPVFAGLLHFFFLAAFSWMCLEGVQLYLMLV----EVFESEYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTVQACWLHVDNYFIWS-FIGPVTFIILLNIIFLVITLCKMVKHSNTLKPDSSRLENINNYRVCDGYYNTDLPGYEDNKPFIKSWVLGAFALLCLLGLTWSFGLLFVN------EETVVMAYLFTAFNAFQGLFIFIFHCALQKKVRKEYGKCFR------HWYCCGGLPTESPHSSVKASTTRTSARYSSGTQSRIRR---------------------------------MWNDTVRKQSESSFISGDINSTSTLNQG-------------------------------------------------MTGNYLLTNPLLRPHGTNNPYNTLLAETVVCNAPS-----------------------------------------------------------------APAFNSPG-------------------------------------------HSLNNARDTSAMDTLPLNGNFNNSYSLRKADYHDGVQVVDCGLSLNDTAFEKMIIS-----------------------------ELVHNNLRGGNKTHNLELKLPVKPVIGGSSSEDDAIVADASSLMHG------DNPGLEFRH-------------KELEAPLIPQRTHSLLYQPQKKVKPEATD----SYVSQLTAEADDHLQSPNRDSLYTSMPNLRDSPYPESSPDMAEDLSP------------------SRRSENEDIYYKSMPNLGAGRHLHMCYQISRGNSDGYIIPINKEGCIPEGDVREGQMQLVTSL----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95490-1", "uniprot_id": "AGRL2_HUMAN", "id": "O95490-1", "name": "Adhesion G protein-coupled receptor L2", "aln": "--MVSSGCRMRS----------LWFIIVISFLPNTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTDCYLPDAFKIMTQRCNNRTQCIVVTGSDVFPDPCPGTYKYLEVQYECVPY----IFVCPGTLKAIVDSPCIYEAEQKAGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNSRQTTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETVYDKRAASNAFMICGVLYVVRSVYQDNESETGKNSIDYIYNTRLNRGEYVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELFKTIISTTSTTSQKGPMSTTVAGSQEGSKGTKPPPAVSTTKIPPITNIFPLPERFCEALDSKGIKWPQTQRGMMVERPCPKGTRGTASYLCMISTGTWNPKGPDLSNCTSHWVNQLAQKIRSGEN-AASLANELAKHTKG-PVFAGDVSSSVRLMEQLVDILDAQLQELKPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRPEALESWKHMNSSEQAHTATMLLDTLEEGAFVLADNLLEPTRVSMPTENIVLEVAVLSTEGQIQDFKFPLG--IKGAGSSIQLSANTVKQNSRNGLAKLVFIIYRSLGQFLSTENATIKLG-ADFIGRNSTIAVN-----------------SHVISVSINKESSRVYLTDPVLFTLPHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDGVHELL--LTVITWVGIVISLVCLAICIFTFCFFRG--LQSDRNTIHKNLCINLFIAEFIFLIGIDKTKYAIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLV----EVFESEYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWS-FIGPVTFIILLNIIFLVITLCKMVKHSNTLKPDSSRLENI------------------------KSWVLGAFALLCLLGLTWSFGLLFIN------EETIVMAYLFTIFNAFQGVFIFIFHCALQKKVRKEYGKCFR------HSYCCGGLPTESPHSSVKASTTRTSARYSSGTQSRIRR---------------------------------MWNDTVRKQSESSFISGDINSTSTLNQG-------------------------------------------------MTGNYLLTNPLLRPHGTNNPYNTLLAETVVCNAPS-----------------------------------------------------------------APVFNSPG-------------------------------------------HSLNNARDTSAMDTLPLNGNFNNSYSLHKGDYNDSVQVVDCGLSLNDTAFEKMIIS-----------------------------ELVHNNLRGSSKTHNLELTLPVKPVIGGSSSEDDAIVADASSLMHS------DNPGLELHH-------------KELEAPLIPQRTHSLLYQPQKKVKSEGTD----SYVSQLTAEAEDHLQSPNRDSLYTSMPNLRDSPYPESSPDMEEDLSP------------------SRRSENEDIYYKSMPNLGAGHQLQMCYQISRGNSDGYIIPINKEGCIPEGDVREGQMQLVTSL----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GRP1-1", "uniprot_id": "A0AC58GRP1_DANRE", "id": "A0AC58GRP1-1", "name": "", "aln": "MWKAESPVRARMGCSEWKSLVLCGLVFVLTVVQSSDGFSRAAMPFGLVRRELSCEGYPIDLRCPGSDVIMIETANYGRTDDKICDADPFQMENINCYLPDAFKIMSQRCNNRTQCIVITGPDVFPDPCPGTYKYLEVQYECVPY----IFVCPGTLKAVGDPSFLYEAEQQAGSWCKDPLQAGDKVYFMPWTPYRTDTLIEYNSLDDFQNSRQTTTYKLPHRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINNANYHDTSPYKWGGKTDIDLAVDENGLWVIYATEQNNGMMVISQLNPYTLRFEATWETTYDKRSASNAFMICGVLYVVRSTYEDNESEVSKSLIDYMYNTKLNHGEYVDIHFPNQYQYIAAVEYNPRDNQLYVWNNFYILRYNLVFGPPDPAHAPPISEASTSPKVLKPTTTTTTTTQPKGQVTTITTTGTRAVNKTPKSPPVLPQTTTPPSLESFPPPERFCESVELRDILWPQTQRGMLVERPCPKGTRGTASYLCVLSTGTWNPKGPDLSNCTSHWVNQVAQKIRSGEN-AANLANELAKHTKG-AIFAGDISSTMRLMEQLVDILDAQLQELRPSEKDSTGRSFNKLQKRERTCRAYMKAIVDTVDNLLRPEALKSWRDMNTTEQTHAATMLLDTLEEGAFVLADNLMEPAIVKVPASNIILDVYVLSTDGQVQDFRFPQS--GRGG-ISIQLSSNTVKLNSRNGVAKLVFALYKNLGQFLSTENATMKLG-QEVNGRNLSVAVN-----------------SDVIAASINKESSRVFISEPVIFTLEHIDMQHYYNSNCSFWNYSERTMMGYWSTQGCKLIHANKSHTTCSCSHLTNFAVLMAHRELLGADKVQELL--LSVISRVGIVVSLICLAMSIFTFCFFRG--LQSDRNTIHKNLCINLFIAELIFLIGIDMTEPKLACSIIAGILHYFFLASFAWMCLEGVQLYLMLV----EVFESEYSRRKYFYMAGYLLPAVVVGVSAAVDFRSYGTKKACWLRMDNHFIWS-FIGPVTFIIMLNLIFLLITMYKMMKHSTSLKPDSSRLEHIN---------------YEDNKPFIKSWVMGGFALLCLLGLTWSFGLFFIS------ESSVVLAYLFTIFNTFQGMFIFTFHCLLQKKVRREYSKCLR------HTYCCSRITTESSHSSTKTSTTRTSARYSSGTQSRIRR---------------------------------MWNDTVRKQSESSFISGDINSTSTLNQGKTKHKTISEPLEG------------------------------------MTGNYLLTNPLLRPQGTNNPYNTLLAETIVCNTPT-----------------------------------------------------------------VPVFHSPVTY-------------------------------------RETRHSVTSGRDTNTFGTLPLNGNFNNSYSLHN--YSDGMQVVDCGLSLNDTAFEKMIIS-----------------------------ELVHNNLR------AAESRIGTKKGAGISRGEE-PVVAETSSLVQVGGDSEMERLGLHHTHP------------RTLEAPLIPQRTHSLLYHTQERARPEAEASHPQSYIGQLPPPAETALPSPNRDSVYTSMPNLRDSPFSESSLDIVQDLSP------------------SKNSPNEDVYYKSMPNLGSGQQLHAYYQMSRDSSEGLIIPVSKDACVPEGDVREGQMQLVTSL----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7G7-4", "uniprot_id": "LPHN_DROME", "id": "A1Z7G7-4", "name": "Latrophilin Cirl", "aln": "-----------------------MLPTILSIS-----YEHISLDLSKYQTAYACEGKKLTIECDPGDVINLIRANYGRFSITICNDHGNVEWSVNCMFPKSLSVLNSRCAHKQSCGVLAATSMFGDPCPGTHKYLEAHYQCISAAQTSTTTNRPSPPPWVLSNGPPIFGNGSGLIHPPGVGAGAPPPPRLPTLPGVVGISGNPGLFNVPPQHTAVTHSTPS---SSTTAVGGGRLKGGATSTTTTKHPAGRHDGLPPPPQLHHHHNHHGEDTASPTKPSSKLPAGGN---ATSPSNTRILTGVGGSGTDDGTLLTTKSSPNRPPGTAASGSVVPGNGSVVRTINNINLNAAG-----------MSGGDDESKLFCG-----------PTHARNLYWN---MTRVGDVNVQPCPGGAAGIAKWRCVLMKRIPDSGYDEYDDDISSTTPAPSGGDCLHNSSSCEPPVSMAHKVNQRLRNFEP---------------------------------------------TWHPATPDLTQCRSLWLNNLEMRVNQRDSSLISIANDMSEVTSSKTLYGGDMLVTTKIIQTVSEKMMHDKETFPDQ------------RQREAMIMELLHCVVKTGSNLLDESQLSSWLDLNPEDQMRVATSLLTGLEYNAFLLADTIIRERSVVQKVKNILLSVRVLETKTIQSSVVFPDSDQWPLSSDRIELPRAALIDNSEGGLVRIVFAAFDRLESILKPSYDHFDLKSSRSYVRNTAILSNDSDVNAGEIQQRLRILNSKVISASLGK-GRHIQLSQPITLTLKHLKTENVTNPTCVFWNYID----HAWSANGCSLESTNRTHSVCSCNHLTNFAILMDVVDEHQHSLFTMFDGNMRIFIYISIGICVVFIVIALLTLKLFNGVFVKSARTSIYTSIYLCLLAIELLFLLGIEQTETSIFCGFITIFLHCAILSGTAWFCYEAFHSYSTLTSDELLLEVDQTPKVNCYYLLSYGLSLSVVAISLVIDPSTYTQNDYCVLMEANALFYATFVIPVLVFFVAAIGYTFLSWIIMCRKSRTGLKTKEHTRLAS----------------------VRFDIRCSFVFLLLLSAVWCSAYFYLRGAKMDDDTADVYGYCFICFNTLLGLYIFVFHCIQNEKIRREYRKYVRQHAWLPKCLRCSKTSISSGIVTGNGPTAGTLCSVSTSKKPKLPLGVSEEAHDDPQQQQQTPVPITEDAIMGATSDCELNEAQQRRTLKSGLMTGTLQAPPQTLGGHVVLERGSTLRSTGHASPTSSAGSTHLIFAHKQQQQQQQQGPLGESYYHQPDYYSWKQPSTGTGGLKTPREYYNNAGAAASSPQQAHEVFYWTQKPNSGHNGKKKRGAGGVPASPSGSLHSRTAAASQVLFYPSYKKTKPGQPTGYPQYAEALDPPLATGNAAAYYQQQQQLRRQQLHQQQQQQQQQQLSSDEEQAEQHAHLLHLQRRAGSQQQLPAPPPHMAQYQQEFMQRQYRNKHSNCDLGMGDAYYNQGSVGGADGGPVYEEILSNRNSDVQHYEVGDFDVDEVYNNSVGTGVFNNMRAAVAAGGSRYGGGSLSGGSVSSRSQQQQLKKQQQQQSLAQQRSARRCTADDDDDEDEEEDEEATAAEQLHDSVCDEDEEEDESDLEDDAHGLPPQSDERMRRLMAMQDEDFKRRFQRQLRKHGAPLDYGALPPGAGPQPEHNGAVFGVSGGVGEGSLRGAFRQQQQQALNAKSPGGRLAVNELFGHGNSGPPLPPANQTPAQKRQQLQKLSPQSTTSSSSHTSHSNPNPHPHQLTHPHPHQHPPHHQQRHLSAMLDENNTVRCYLEPLAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::. :.: :: :. : :*** : :.* .*** : ***** . .**: . . :* :*.::.::..** :: .* *::...:* ******:****.:*:*:. . : . . : :* : *. * . : .* :. .: :.*:. * .: .* .* : . * . : * . . :: : *. . *.. .*... * . .:: . * .. . : :. .. :*:.. :: * ***: : * . .. :. *: . * . * . : ** : * . * *. .. : . . * . . **. . . * **:* ***::* * *:*:: ::.. :. .:**:::: *.. ::.**: : :::: : : : : : : . ::** ::.:*.* .*** . *..* .:*. :* :.** ** ** .**:***.::. * ..**:*.* **.*. ... * . *:*. :: **..*:.::** : * :*... ..* ** :: * * *::.*:.* . :: :::*: ::: *:. :: *..* **** : **::**.* :*::::.*:*.******:** : . . : : :: :.* :.:: :.:.::*: :*.* ::* *.:*:..: : *: *::**:**: *: : * .:: :** :*:. :*:* *..: * *. : .: .: : :*: .* :. **.:* .:* :* . * * * :::: *: ** .::: : : .:: * ::* : ..: . : : .*.:* **. .*. . ::: : : * .* * **:: *::** *** ::*:*:** * .* : *. . .* : : .*: * . *:..:.:: : : *: :*.:::* :::.. * .. * .:* . * :.* : ...:* . .:..* * : * :.: ** . .*. . : :*.*.:.*: ::: :. : *:** . : . . . . *:. *. : : . . . * . .:: *. : . ::. . . * : :.* :**. . . : . .* * .. .: ::: ..* :* :.:..* : * .: . . :::: . * .** ", "identical_positions": 256, "similar_positions": 498, "identity": "13.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000607-52", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GLZ3-1", "uniprot_id": "A0A8I6GLZ3_RAT", "id": "A0A8I6GLZ3-1", "name": "histone acetyltransferase", "aln": "-----MVKLANPLYTEWILEAVQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDHPGRFSSVKPGTFPKPTKGPKGPPCNDLRNVDWNKLLKRAIEGLEEPSGSSLKSIEKYLRSQSDLTGTTDHPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNTGSSDGRGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELVSCADCGSSGHPSCLKFCPELTANVKALRWQCIECKTCSACRVQGKNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKK-GRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDEGSVNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKTTTSSTYISASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHMLATGTTQKLKPPPSALPPPAPISGQSPSSQ---KSSTSTSSAPTQSSSSRSSEPSFSSLINSSQLKALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTEFSSTAKAKACFFGKRDFR----SRFLSHSSCS-WGMTRGHIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLADGRINPDQDNDTEIKISIKQESMDVNVMGNKDLVTEEDLDVFKQAQELSWEKIECESGVED---------CGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKG---------CHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSYLAYWKSVILEYLYRHH-ERHISIKAISRATGMCPHDIATTLQYLHMIDRRDGRFVIIRRE------KLILGHMEKLKNCSRPNEVDPESLRWTPILISNAVVSEEEREAEKEAERLMEQASCWEKEEQENLSSRVTSRQSSAKVQSKNKYLHSPERRPVAGERGQLLGLSKESSEEEEEEEDDEDEEEEEE------------------EEE-SIPTSPPRLTKPQSVSIKRKRPFVVKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDE----ERPMPRLEPTCEIQVEEAGRKPVLRKAFQHQPGKKRQTEEGDGKDNHFFKNAALCRNDVDDDAEHL------EEGSRDSAEPLKCRQVWPKAAKRGLSKWRQSKERRPGLKLNLCTPPETPMEPEGLTKVVKEQKGISEDKGSP--VGEDREVTETEEALLPQDGNGREETGTPVSPHKSPGGKADEEDLIKGEEEEEEEG------------------TTEKDPDGAKSKEKAEAEISMEKE--DAVHLDDHEEDEDEEEEPSHNEDHDADDEDDGHMEATNVDRGDLPKEAFKDALEGQEAFLGLSIQPSHSDPEGLVNCGGDLAVSCGSEPKELAG--DAGTAPESDSE----------------------------------------------------------------LPE-EQTQEQDQEKSNGADTELKDGGTATVEIDSETVQAVQSLTQENREQDDTFQDCAETQEACRSLQNYTHTDQSPQIATTLDECQQSDHSSPVSSVHSHPGQSVRSVNSPS---------------------------VPALENSYAQISPDQTAITVPPLQN-METSPMMDVPSVSDHSQQVVDSGFSDLG---------SIESTTENYENPSSYDSTMGGSICGN-----SSSQNSCSYGSLTSS-SLTQSSCAVTQQMS----NISGSCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQ-----------------------------------------QLAQCSMAANFTPP-MQLADIPETSN--ANIGLYERMGQSD------------------FGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSA--AATSYAN-SASLSTPLS--NTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASKGP----VSMRTKSASLSPAAATHQSQIYGR----------------SQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQTP------PHSNMMYTAPGHHGYMNTGMSKQSLNGSYMRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BRB7-1", "uniprot_id": "KAT6B_MOUSE", "id": "Q8BRB7-1", "name": "Histone acetyltransferase KAT6B", "aln": "-----MVKLANPLYTEWILEAVQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGTFPKPTKGSKGPPCNDLRNVDWNKLLKRAIEGLEEPNGSSLKNIEKYLRSQSDLTGTTNHPAFQQRLRLGAKRAVNNGRLLKEGPQYRVNSGSSDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTANVKALRWQCIECKTCSACRVQGKNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKK-GRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDEGSMSAFTGRGSPGRGQKTKVSTTPSSGHAASGKHSSSRLAVTDPTRPGATTKTTTSSTYISASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLAT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DTDIKISIKQESADVSLVGNKELVTEEDLDVFKQAQELSWEKIECESGVED---------CGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKG---------CHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSYLAYWKSVILEYLYRHH-ERHISIKAISRATGMCPHDIATTLQHLHMIDRRDGRFVIIRRE------KLILGHMEKLKNCSRPNELDPESLRWTPMLISNAVVSEEEREAEKEAERLMEQASCWEKEEQEILSSRVSSRQSSAKVQSKNKYLHSPERRPVAGERGQLLELSKESSEEEEEEEEEDDEEEEEE------------------EEEESIQTSPPRLTKPQSVSIKRKRPFVVKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDE----ERPMPQLEPTCEIPVEEGGRKPVLRKAFPHQPGKKRQTEEEEGEDNHFFKTAALCRKDVDDDAEHL------KEGSKDNPEPLKCRQVWPKGAKRGLSKWKQSKERKTGFKLNLYTPPETPMEPEDQVTIE-EQKELSEDKGSP--VGMEREVTETVDALLPQEGSRREETGIPVSPHKSPGGKVDEEDLIRGEEEGEEEGEEEGEREEQEEEEEV---TTEKDLDGAKSKENPEPEISMEKE--DPVHLGDHEEDEDEEEEPSHNEDHDADDEDDGHMEAANMERGDLPRETFKDALEGQEAFLDLSIQPSHSNPEVLMNCGVDLTMSCNSEPKELAG--DTGTAPESDAE----------------------------------------------------------------PPE-EQTQKQDQKNSDGVDAELEEGGPAAVEIDSETAQAVQSLTQENREHDDTFPDCAETQEACRSLQNYTHTDQSPQIATTLDECQQSDHSSPVSSVHSHPGQSVRSVNSPS---------------------------VPALENSYAQISPDQTAITVPPLQN-METSPMMDVPSVSDHSQQVVDSGFSDLG---------SIESTTENYENPSSYDSTMGGSICGN-----GSSQNSCSYSSLTSS-NLTQNSCAVTQQMS----NISGSCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQ-----------------------------------------QLAQCSMAANFTPP-MQLADIPETSN--ANIGLYERMGQSD------------------FGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSA--AVTSYAN-SASLSTPLS--NTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASKGH----VSMRTKAASLSPAAATHQSQIYGR----------------SQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGSQPYAQQPMQTP------PHANMMYTAPGHHGYMNTGMSKQSLNGSYMRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WYB5-1", "uniprot_id": "KAT6B_HUMAN", "id": "Q8WYB5-1", "name": "Histone acetyltransferase KAT6B", "aln": "-----MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGS-CNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKK-GRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPDGRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLATGTTQKLKPPPSSLPPPTPISGQSPSSQ---KSSTATSSPSPQSSSSQCSVPSLSSLTTNSQLKALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIR----SRFISHSSSSSWGMARGSIFKAIAHFKRTTFLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKPDQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVED---------CGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKG---------CHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSYLAYWKSVILEYLYHHH-ERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRRE------KLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEE----EEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDE----ERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNL------KEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVE-EQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKP-EDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKE--DSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAG--DPEAVPESDEE----------------------------------------------------------------PPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPS---------------------------VPALENSYAQISPDQSAISVPSLQN-METSPMMDVPSVSDHSQQVVDSGFSDLG---------SIESTTENYENPSSYDSTMGGSICGN-----GSSQNSCSYSNLTSS-SLTQSSCAVTQQMS----NISGSCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQ-----------------------------------------QLAQCSMAANFTPP-MQLAEIPETSN--ANIGLYERMGQSD------------------FGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSA--AVTSYAN-SASLSTPLS--NTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASKGH----ISMRTKSASLSPAAATHQSQIYGR----------------SQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQTP------PHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BER5-1", "uniprot_id": "A0A8M3BER5_DANRE", "id": "A0A8M3BER5-1", "name": "histone acetyltransferase", "aln": "-----MVKLANPLYTEWILEAIQKIKRQKQRPSEERICHAVSSTRGLDKGVVLHQLELAVKDGSILKVTSKGCASYKDPDNPGRITPFKLGGSGTVSVGSVIP-AGDLRHVDWNKILRRAIEGLGVPSGSSLRNIERFLRSQGDLVNVVANPRFQQRLRLAAKRAVNNGRLLKDGPLYRLNSGGLGGKSCFRNVGVFGVDLPPVTLLPHERDQPRADPIPICSFCLGTKESNRDKRPEELLSCADCGSSGHPSCLKFSADLTANVKALRWQCIECKTCSSCQIQGKNADEMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKEQEGKRLLHKTAAQIKRRYAKP-GRPRKNLAHPTMSDSGGPGSV-ELSEKARHGRGSISTFCTPPSS---------STFIPTTD----GRSLTDPLTSTPTLTTLPPINKKTKGLIDGLSKFFTPSPLGRRLRGEASGSSNQHRPRKRGYRKHHASMMTPGVR----LNAPSSVLLTPSPSQGHSPISLNPTQSSSPSSAHSPHSSSSQSSGPSLSSLPGNSQLKGLFDGLSHIFTTQGQSRQKGLPSYAPPKRVRRTQDMSTSPKMSLQLQGKKPVKGFCSKLASLASSASGWPPKRGRPFKSALHFKRTPILRKHKLLGRFRFKASPQRENITPGKGRLADGRVKPDPNHAFNVERCLRREPQEGRMTLVNDHVAEEDLKLFRHVKELTAKKNGGDQ--------------GQSPPLIEFGKYEIQTWYSSPYPPEYLRLPKLYLCEFCLKYMKSQDILQRHSKKCGWFHPPANEIYRKDNLSVFEVDGNISKIFCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDEKG---------CHLVGYFSKEKLCQQKYNVSCIMIMPQFQRQGFGRFLIDFSYLLSRLEGQAGSPEKPLSDLGRLSYLAYWKSVILEYLHNHP-DKSVSIRGMSRATGMCPHDIATTLQQLNMIDFQDGRFVIIQRH------QLIEEHMDRLRVKPRLHEVDPDCLSWTPALVCRSPPVDLKSALALQARDHRADYTASTRNLAMGMG-YIGTRPPLTKCKNFRRRYSDP---LFGNSTGKDFEVSEESSSDDDDDNNDDDDDDEDG-------------------EDSAVQSQS-------GQGLKRRRAPTMRRKRGRRRTRINSSVTTETILERTEVLDEPFENSDV----ESPLPEHSRRCCSEDEEEEKS---QRSAVCRPGRPRTNEE----DNHSNQ----------SKEEEN------VEVKKDNPRPAKRKKGWPKGVKRGPPKWR-LKERKMGFKLNLYTPPETPMVTVEQEQDD-EQDASPASFSGP---------CQSFRESRPEDPELDTCVSVPPSPEPPKSHKVNEDESTDKSDTVENSPSADDTNETTPGPID----DPEQSTQNAEELEDLKPEGETEGRPVKGSGEGDEEEDEDEEPEPSHLDDHDADDEDDSHEQRMEDPVPLPERDLTEDTEPSPSNNNNKQPEEQPSPGEPPSHCSEELASESALVNLGMQDGDTVDSDHTPDSE----------------------------------------------------------------TEEEDNLEKPEEKQMGPLTPAIKEDHNICPELDMETAQAVQSLTQES-EQERHFQDCAETQEACHSLQRYVHVEQSPQMTP-VDDCQQSDHSSPLSSVHSHPSQSVRSVNSPA---------------------------VSILESGYTQISPDQGTVSVHSLHNNMETSPIMDVPSVSDHSQQVVDSGFSDLG---------SIESTTENYENPSSYDSTLGNSICGTGAGAGASSQSSCSYGNLSSGGSHSQSSCAVSQQMAGPVVNNTGACSMLQQTSMSSPQGCSVKSPQGCVPERQPSHSHGHGH--GHGHGHGHSHSHHHSHHQHHPHHQHHQHPQHQYQQPLSHCSMPASFPPPPMQLPDIPESNNPSTNLGLYDRMGQGE------------------YGTGHYG------HLHKLQQLTNTIMDHSLPFSHSASHSIPSYANNNGSLSTQLGPHNPTLVSLSQP----GGGPQSQSTVTPPPNMTPPPM-----MLQRNMATPNMNLAPSQRLQTQMPPKNHHHHPVSIRSKSAPLPP---HHQQQMYGRG---------------PQSVAMQAPGRTLAMPTRMNMGVNLMPAPAYNVNSMNVNVN--MAMNTYRVTQPMMNGGYHGNPTYMNQSPQY--SMQMGMMGTQPYPQQPMQAP------PHGNMMYSPAGHHSYVNTGMSKQPLNGPYMRR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P34218-1", "uniprot_id": "SAS3_YEAST", "id": "P34218-1", "name": "Histone acetyltransferase SAS3", "aln": "----------------------MSLTANDESPKPKKNALLKN-----------------------LEIDDLIHSQFVRSDTNG----------------------------------HRTTRRLFNSDASISHRIRGSVRSDKGLN-KIKKGLISQQSKLASENSSQN----------------IVNRDNKMGAVSFPIIEPNIEVSEELKVRIKYDSIKFFNFER-------------LISKSSVIAPLVNKNITSSGPLIG---------FQRRVNRLKQTWDLATENMEYPYSSDN-------------------------------TPFRDNDSWQWYVPYGGTIKKMKDFSTKRTLPTWEDKIKFLTFLE-----------------------------------------------------------NSKSATYINGNVSLCNHNETDQENEDRKKRKGKVPRIKNKVWFS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QIEYIVLRNYEIKPWYTSPFPEHINQNKMVFICEFCLKYMTSRYTFYRHQLKCLTFKPPGNEIYRDGKLSVWEIDGRENVLYCQNLCLLAKCFINSKTLYYDVEPFIFYILTEREDTENHPYQNAAKFHFVGYFSKEKFNSNDYNLSCILTLPIYQRKGYGQFLMEFSYLLSRKESKFGTPEKPLSDLGLLTYRTFWKIKCAEVLLKLR-DSARRRSNNKNEDTFQQVSLNDIAKLTGMIPTD----VVFGLE------QLQVLYRHKTRSLSSLDDFN-----------------------------YIIKIDSWNRIENIYKTWSSKNYPR----VKYDKLLWEPIILGPSFGINGMMNLEPTALADEALTNETMAPVISNN------------------------------------THIENYNNSRAHNKRRRRRRRSSEHKTSKLHVNNIIEPEVPATDFFE----DTVSSLTEYMCDYKNTN--------------------------------------------NDRLI------YQAEKRVLESIHDRKGIPRSKFSTETHWELCFTIKN---------SETPLG---------------------------------------NHAARRNDTGISSLEQDEVENDVDTELYVG---------------------------------ENAKEDEDEDEDFTLDDD-------IEDEQISEENDEEEDTYEEDSDDDEDGKRKGQEQDENDIESHIRKERVRKRRKITLIEDDEE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W1A9-1", "uniprot_id": "Q9W1A9_DROME", "id": "Q9W1A9-1", "name": "histone acetyltransferase", "aln": "MMRESAHDINMDTWNQWILEAISKIRSQKQRPSVQRICQAIGTHHKFHEDIVAEKLEKAVESGAVIKVYNKGLHSYKAPMAKRRVKVDKN--------------------TNLYKLVAKAVHDLGECEGSTIKSIENYIQK-FNCIDLSPNVDFKAVIKASIKKAVDAGFLIQEGKLYKKGKSLTTPRKCAPVSEVVIKGEESCTHCSGNSQKNLNGIPEPLSSCKQCG---------ISLHTTCANIAGRCKSQSYVLLYMLVTKGTIWDCQNCADCAVCKMRNR-GPCLLQCFVCKDHFHLTCLDTIPDKKPKHPYRCKTCSKQGFDTPKLVKKDNSRIKMEAERMTPSYKYASNKRQSIKKDGNIESPSTSKLCVYNDGNGQRRKVPASLSSRKMNHSEDQFEFPSKQKRSQILQGGYLASQETRKRTFSDLSSTSSSSESEDEDDEDDDRNRNGDDNDQDESTSSDSCTSSSSDSDSSESSSDTSEWDDEYDEEEDYDTDRSTIREKNVFESGKQSCAKLSTGDGLGSPQNNELGSENWGFAAVAKNPIDIFVKSKHNSNVKGIGYSKPAASTFATSPAANRVQKSTPVASSTPEKNSAPIGGMTIKRQTANGQKKKIVPLKSMPLEAGKSYEKCEDDIPYLTEETVMKVQLLEEIERSRETHSQADGKREMNNDEDAPGESTKRANPFENQPLPPGVTATDVELYQEVLHKAVVQMSNNHIEKVNDVSLKSGQNTQSPKSIQIGKWDIETWYSSPFPQEYARLLKLFLCEFCLKYTKSRSVLDRHQNKCIWKQPPGTEIFRQGNISVFEVDGNVNKIYCQNLCLLAKFFLDHKTLYYDVEPFLFYILTKNDQSG---------CHLVGYFSKEKHCTQKYNVSCILTMPQYQRQGYGRFLIDFSYLLSREEGQLGTPEKPLSDLGRLSYFSYWKSVVLEYLYKHRNYTKITFKDIAIKTGLAISDIALAFELLNFIKLRKNDGDIRYQINVKIEWKKVLAHHNKMANSKTRIIIEPDCLRWSPLLSVSKLPNIIKPISNREYLSNQMETNSSFKEINEDKISVKQGVSTSSKVNQESSELSTKNRGPSSEKLIDERENQRKRAYPEEFLKSASNEAKKPKLTAPQPNLEDQSFGELSDSSDCKSSKDLSEQLTKRAQRLAKRNDLIPHTNKRKHFDRPLENNTTSTDHNPPAQSQADTAGTENGHKSEETAAKENCKNVVEKEHVDKPVNIMPKLRGKQSNGKRSEEPQFNENPTSDPVAVASLSPAKEITREPVKVAKTESPGKNQESAKHDAEPNSVSDQVLDAVAKKTKKTLFSDVASYNTEDVKYNSEEKPMAIAQEPKESPTEAGIKETKPLEVPEQKAKAKSPEKPATVAETVLQHVHAPVNTEKISTEESKLELDVHYLKLSPDSALNPPVASVQKPVPEPPAPKEKAKDLQAAQPSEALQKQ----PEIEMVKKTETKTETPVSNPPSNRTDVSSLVEQPVKAAPEKVEQPMVKEAVDIKDKALKKPVPDVPVVKPEATSCEKKIDHSKTKVFHEKEAIKTDQQLVQVKEEEKSNARAPSAPIPIRDKIQLKGNEHAQLQNSIPSQFPLNQMPNYHTSQYWQWEYYGYNLSHLDASQKGQKQFHKDLATTMAYTHNFTQNLYQSANLAMQHAHHQMHQTKEKHKVERKNSGKKEEQNKVVSSVNVVSTAREDAHVQHCNEYAANNQAALYNQKCASQQKQAQQMKSLANVQNPVPRQSNSNAPESTVLMPNPVISQAGSVPAKQKVEHGVNSTSVISREGKLNKIGHSNIHATAQHANLQVGGGQSDVNPNMVYNTESSANSAMQHYDCGISAQINMDSPANIGSAIAHGPQEISATSNVHMHQPHRQFSDCSMQNQPVTTPMHMSIQNSHMQQQNNLNLNLAPEGSSNINLLSNPQHQHQSRKLNAQADIAVSSPTPSHRATTPKQIRSGNTQQRDAKNAAPPTTTTNTHHQIPQGGAAANISKSHHDSLHNLQFSQHGHQQNMQPIDYVPIPQISQNFSANPSNYDIVGMPAVIQQRMSLNGSVHSLANSHQRIEQPSSACAVNNFYLQNNMPAAENAPRVPVSSSLGGPPTAGNNDQRQAGQDSITTANSSGATASLAGNLCSLSKLQQLTNCLESQPCNTSPGAQVNLAPSPHHPIPPNSTPPPHLLMQNRNISTPPNMLQTQVTPLQYKYYPGNMNIPPITSAQNTSRNTRNTPSAPVQHTSTPMGSGNNRTANVHISPNLMAPYGAINSYRMSPQQSPPTGSYSSGGDYPNSQIPMQMMNMQSQYQDACVLQRGTPSNPMYPTYSPYLPLNGSIRR-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :.: *. :: . . ::: . .: . :: . * ..* : *. ::. . : :. : . :.: : : . : . . : : . . . : : . : .. : .: : : : . . ..: :. . . .:. .. .. . . * : :::*:.**:**:* . : :::******* .*: : **. ** :**..**:* .:**:*:**. . ::********* *:: **********:**:**:.::. *:******** :.**:***: :* .**:*:*:**::******* *.: *:********* *:* ::** * * . : .: : :* : : : .: .: . . : . . : :. . : . . : :: :: * . *:. : : . : . . . . : .. : :. :. . . : : *:. : . . : :: . : : * .. : : :: ", "identical_positions": 107, "similar_positions": 203, "identity": "4.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000607-58", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TYE7-1", "uniprot_id": "TLCD5_MOUSE", "id": "Q3TYE7-1", "name": "TLC domain-containing protein 5", "aln": "MAVGLCVQVLCSLGGWLSLYTSFCCLNKHRSCEWSCRLVTFTHGVLSIGLSAYIGFIDGPWPFTHPGSPNTPLQVHVLCLTLGYFIFDLGWCIYFQSEGPLMLAHHTLSILGIIMALALGESGTEVNAVLFGSEITNPLLQMRWFLRETGHYHSFTGDVVDFLFVALFTGVRIGVGAHLLFCEMVSPTPKWFVKVGGVAMYAVSWCFMVSIWRFAWKKSIKKYHAWRSRRNEERQLRHNGHLKTH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZRR5-1", "uniprot_id": "TLCD5_HUMAN", "id": "Q6ZRR5-1", "name": "TLC domain-containing protein 5", "aln": "MALALCLQVLCSLCGWLSLYISFCHLNKHRSYEWSCRLVTFTHGVLSIGLSAYIGFIDGPWPFTHPGSPNTPLQVHVLCLTLGYFIFDLGWCVYFQSEGALMLAHHTLSILGIIMALVLGESGTEVNAVLFGSELTNPLLQMRWFLRETGHYHSFTGDVVDFLFVALFTGVRIGVGACLLFCEMVSPTPKWFVKAGGVAMYAVSWCFMFSIWRFAWRKSIKKYHAWRSRRSEERQLKHNGHLKIH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F142-1", "uniprot_id": "E7F142_DANRE", "id": "E7F142-1", "name": "", "aln": "MSP-LVLGVGVCLAGWIALYALLCYTNGSCGYEWNCRLVTLFHGILAVCITAYIGYIDGPWPFTYPGTKNTPLQISALVVSLGYFIFDMAWCVYFRTEGLVMLAHHTMSILGILLTLWLEESGIESCAVLFGSEITNPLLQTRWFLKHSGRYDSILGDVVDILFVALFVFMRIFVGGAMLYCELISPRPKFIIKCGGVAMYALSWVFMADIVRFTYR----KYQVWMNRHKMMAEVNG-LNVKRD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * : * .* **::** :* * . **.*****: **:*:: ::****:********:**: *****: .* ::*******:.**:**::** :******:*****:::* * *** * *******:****** ****:.:*:*.*: *****:******. :** **. :*:**::** **:::* *******:** ** .* **::: **:.* .*:. ::. ::* .", "identical_positions": 132, "similar_positions": 65, "identity": "53.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000607-65", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08719-1", "uniprot_id": "EVL_RAT", "id": "O08719-1", "name": "Ena/VASP-like protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFAF---EEFSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQDQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMN----SQEGGPSTQRQVQNGPS------PEEMDIQRR------QVMEQ--QHRQESLERRIS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATGPILPPGHPSSAASAT-------FSCSGPPPPP-----PPPVPPPPTGSTPPPPPPLPAGGAQGT---NHDESSASGLAAALAGAKLRRVQRPEDASGGSSPSGTSKSDANRAS---SGGGGGGLMEEMNKLLAKRRKAASQTDKPADRKEDENQTEDPSTSPSPGSRATSQPPNSSEAGRKPWERSNSVEKPVSSLLSRTPSVAKSPEAKSPLQSQPHSRVKPAGSVNDVGLDALDLDRMKQEILEEVVRELHKVKEEIIDAIRQELSGISTT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70429-1", "uniprot_id": "EVL_MOUSE", "id": "P70429-1", "name": "Ena/VASP-like protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASSTFRVVGVKLQDQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMN----SQEGGPSTQRQVQNGPS------PEEMDIQRR------QVMEQ--QHRQESLERRIS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATGPILPPGHPSSAASTT-------LSCSGPPPPP-----PPPVPPPPTGSTPPPPPPLPAGGAQGT---NHDESSASGLAAALAGAKLRRVQRPEDASGGSSPSGTSKSDANRAS---SGGGGGGLMEEMNKLLAKRRKAASQTDKPADRKEDESQTEDPSTSPSPGTRATSQPPNSSEAGRKPWERSNSVEKPVSSLLSRTPSVAKSPEAKSPLQSQPHSRVKPAGSVNDVGLDALDLDRMKQEILEEVVRELHKVKEEIIDAIRQELSGISTT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UI08-1", "uniprot_id": "EVL_HUMAN", "id": "Q9UI08-1", "name": "Ena/VASP-like protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQDQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMN----SQEGGPSSQRQVQNGPS------PDEMDIQRR------QVMEQHQQQRQESLERRTS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATGPILPPGHPSSAASAP-------VSCSGPPPPP-----PPPVPPPPTGATPPPPPPLPAGGAQGS---SHDESSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRAS---SGGGGGGLMEEMNKLLAKRRKAASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSILSRTPSVAKSPEAKSPLQSQPHSRMKPAGSVNDMALDAFDLDRMKQEILEEVVRELHKVKEEIIDAIRQELSGISTT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B578-1", "uniprot_id": "A0A8M2B578_DANRE", "id": "A0A8M2B578-1", "name": "Ena/VASP-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAHSVQFCLPQSHSDSGLHTSG---CKISEQSICQARASVMIYDDTSKKWVPVKPGQQGFSRINIYHNTVNNSFRVVGVKLQDQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSTAMLFALNVLG----SQDAGPGAHR--QNGPV------TDDGEAQRR------QMMDQ--HQMQMERERRTSGSAVSTLQFKVSASASQSETSLHDLRQYRANTLPPSYAHLNPAASSAHTAIPPLQEGGYHMVDSPQKKAQQLSQLSTSLASAFSPVQQGVVPPPRNIKQIPLSPPTSQQDLKHATWSSAHMYAPLPAASPPVVMAVKQPGLPVALPLPPLNNGPKAPSNTSHLDPIMHLQQSSNGQAEECYPYQSPSGGPLHPHYPIQESSCPLPPLIGQPVQGPGLHPQQLYQTTPPFETTPTSHTTPKTSPSPVYQNAAAASTGPPVPPGHPSMLSAAPPVHPPTSASMVGPPAPP-----PPPGPPPPGPPPPGPPPPVTGPPPTPPPLPAGGGPAPSGLAAALAGAKLRKVQRPEESSSSSNNSSNSKNDASRSSGG-SGGGGEGLMQEMNALLARRRKAS---EKPED-----SQNEESNGSPS------SSRGQNSDPVKKPWERANSADK-----------------------SSAVSRAKPLGSTSDA--ESFDFDRMKQEILEEVVRELQKVKEEIIDAIRRELLRIGST", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8T4F7-4", "uniprot_id": "ENA_DROME", "id": "Q8T4F7-4", "name": "Protein enabled", "aln": "MAMKKLYAKTSFTSKKPSSAANSTPILAYHQQQHQQPGNGICEFQVVAPGHSGELMIRRSQSMHHKMSPPVGGLGSKSEYYSIEELQELDLLDYRHPMYHHYQQQELRQRYHEHEQLVLQLPKATSPKAGPIYEAPQRSQQQQDQMLYVPTAAQRDSSSSAAATSIASSSTLTSSPSPSSSSSLIFSTLRKCVSPSNPSVNPNQPSKTQPSKLGCSMSFSIRTTTATAATAAAANAATATLSTQQQQQQAQQQHKQHLYSNIHHYLIRQQQQKQHYTLQRRHNSVKDKFIGGITTIFAEQSIIGARASVMVYDDNQKKWVPSGS-SSGLSKVQIYHHQQNNTFRVVGRKLQDHEVVINCSILKGLKYNQATATFHQWRDSKFVYGLNFSSQNDAENFARAMMHALEVLSGRVANNPGGPPTNGNGYEEDMGYRTMTSEDAAILRQNNSIGGHVTPSAQTPTSQTNQNNIPQSPPTPQGHHRTSSAPPAPQPQQQQQQQQAQQMGQPGSHYGPTGNGPTSNGLPQQVNSQIPPAPQQQPQQQQFQQQQQQQQYQQMVQAGYAPSQQYQQPHYVLSNSNPNLTVHQYPTQQAQQQPPQAPQPPLQNGGMYMVGHGHLP-------SSASANSVVYASQQQMLPQAHPQAPQAPTMPGPGYGGPPVPPPQQQAENPYGQVPMPPPMNPSQQQQPGQVPLNRMSSQGGPGGPPAPAPPPPPPSFGGAAGGGPPPPAPPQMFNGAPPPPAMGGGPPPAPPAPPAMGGGPPPAPGGPGAPPPPPPPPGLGGAPKKE---DPQADLMGSLASQLQQIKLKKNKVTTSAPENSGSSTSSGGSGNYGTIGRSSNGMASMMDEMAKTLARRRAQAEKKDPDPEAEVKKRPWEKSNTLPHK-----LSGGAGSGSAGSGHEGANGNSGGAGSNTTNSGGESPRPMRKRFGSASEETILKVNGDGLSLALSNGDLDTLKAEIVREMRLEIQKVKNEIIDAIKSEFNRR---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::**** ******:***..***** . ..*:*:::***: ..:***** ****::**** **:*********.*******:: ******:*:::* .*: **:.**:::. .: .** :: : .:: *: :: . . :.. . : * **. *. .:. . .**.** *** * * ..* **** . . ..**: : **:: : . .:. .*. * .* .... .: *..* .:*:** **:** : : : *... * . .* . . * :*. . :. : * *. . . *:* :* **:.*: *::***:******: *: ", "identical_positions": 128, "similar_positions": 120, "identity": "12.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000607-70", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZYX7-1", "uniprot_id": "A0A8I5ZYX7_RAT", "id": "A0A8I5ZYX7-1", "name": "", "aln": "EALKDCHGLPEPKRQHPLIGAPGSAPRAGGHHPNERRLGRLFLQDPPTVRASRRWAPTAVPRAGRGQGLPGPAGARTPITGSHQEPGRRALAQPRSPARLFFSIHADAQSCRRRRQRGRRRRPSGLAGGRGAGTFPRPAARAAHRRRCRRGPGTRPGQSGRAGWGGSVAIAGLVSPAGPPFLPAAGPPPPAAPSRAPAEPTHCRRAGAGSRGGAQRAWSARPAPLRLPIRVARRRLAGARGCPGAAAPPLPQPPRLLRPPPIPGKGRSVGKGWLSFNQRLSVSGISVHAPPAAERRAAAQLTPPCPPRDPPGSPRSATMKRAHPDYSSSDSE--------LDETIEVEKESADENGNLSSALGSMSPTTSSQVLARKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGY-FDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHGGLG--------------------------------HIPWGSAFGHHP-HIAHPLLLPQN---GHGNAGTTASP-----------------TEPHHQGRLASAHPEAPALRAPPS------------------GGLGPVLPVVTSASKLSPPLLSSVASLSAFPFSFSSFHLLSP-----STPSQAANLGKPYRPWGTEIGAF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV93-1", "uniprot_id": "HEY1_MOUSE", "id": "Q9WV93-1", "name": "Hairy/enhancer-of-split related with YRPW motif protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKRAHPDYSSSDSE--------LDETIEVEKESADENGNLSSALCSMSPTTSSQVLARKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGY-FDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLLVRLVSHLNNYASQREAASGAHGGLG--------------------------------HIPWGSAFGHHP-HIAHPLLLPQN---GHGNAGTAASP-----------------TEPHHQGRLASAHPEAPALRAPPS------------------GGLGPVLPVVTSASKLSPPLLSSVASLSAFPFSFSSFHLLSP-----STPTQAANLGKPYRPWGTEIGAF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5J3-1", "uniprot_id": "HEY1_HUMAN", "id": "Q9Y5J3-1", "name": "Hairy/enhancer-of-split related with YRPW motif protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKRAHPEYSSSDSE--------LDETIEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGY-FDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLG--------------------------------HIPWGTVFGHHP-HIAHPLLLPQN---GHGNAGTTASP-----------------TEPHHQGRLGSAHPEAPALRAPPS------------------GSLGPVLPVVTSASKLSPPLLSSVASLSAFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRPWGTEIGAF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AXV6-1", "uniprot_id": "HEY1_DANRE", "id": "Q8AXV6-1", "name": "Hairy/enhancer-of-split related with YRPW motif protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKRNH-DFSSSDSE--------LDENIEVEKESADENAGANSPLGSMSPSTTSQVQARKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHAAGGKGY-FDAHALAMDYRGLGFRECLAETARYLSIIEGLDNTDPLRIRLVSHLNSYASQRE----AHSGLG--------------------------------HLAWGSAFGTPPSHLAHHLLLQQQQQQGAPLARSTSSPPSSNSSSPSSSSPSAPSTEPRLSGTVISEAGQTGPLRVPPS------------------TSLPPGLTPPT-ASKLSPPLLTSLSSLSAFPFPLSAFPLLSPS--SLGPATPSSSLGKPYRPWSMEIGAF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KM13-1", "uniprot_id": "HEY_DROME", "id": "Q7KM13-1", "name": "Hairy/enhancer-of-split related with YRPW motif protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDHNMHVNAPSLHHWGYAAGPGVVMPGATATTPQSHWVPPPQSHHSAHSNHSHGHSQGHSHGIGSLKRTLSESDCDDLYSEESSKEQISPSEPGSCQLMSRKKRRGVIEKKRRDRINSSLTELKRLVPSAYEKQGSAKLEKAEILQLTVEHLKSLQSKTLDSLSYDPQRVAMDYHIIGFRECAAEVARYLVTIEGMDIQDPLRLRLMSHLQYFVQQRELSAKSCASPGGWSPAAPSSSGYQPNCAAAPYQSYAAPANPGAYVSSYPTLSASPSQQAQQLGGRTSVSRTSGSAVTESLPSHDLHSDSSSQQQQQQQQQQQQQQQHQQQQHQQQQQRTQTTPQPTQQQHYTHDHSAVHSEQQVPTYIELTNSNRPAAIGSDSLSYSAAPQYPVSGLPGQDYNN-SSVLQYATPNGAKPYRPWGAEMAY-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :.* ..*: *...:. .. . . .. * * . :.*: :**:***:***:******.**:**:******:***************:**:*** *:: .. :*.: :****: :***** **.**** ***:* *** :**:***: :..*** : .. * ::. ..:. * : *: * . * : : * : : . . : *. .: * * :.: :. *:: :* :....: . :.. .******. *:. ", "identical_positions": 101, "similar_positions": 94, "identity": "14.39%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000607-75", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y3T9-1", "uniprot_id": "NOC2L_HUMAN", "id": "Q9Y3T9-1", "name": "Nucleolar complex protein 2 homolog", "aln": "MAAAGSRKRRLAELTVDEFLASGFDSESESESENSPQAETREAREAARSPDKPGG----SPSASRRKGRASEHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDSDSSEEEEGP----FHSLPDVLEEASEEEDGAEEGEDGDRVPRGLKGKKN---SVPVTVAMVERWKQAAKQRLTPKLFHEVVQAFRAAVATTRGDQESAEANKFQVTDSAAFNALVTFCIRDLIGCLQKLLFGKVA-KDSSRMLQPSSSPLWGKLRVDIKAYLGSAIQLVSCLSETTVLAAVLRHISVLVPCFLTFPKQCRMLLKRMVIVWSTGEESLRVLAFLVLSRVCRHKKDTFLGPVLKQMYITYVRNCKFTSPGALPFISFMQWTLTELLALEPGVAYQHAFLYIRQLAIHLRNAMTTRKKETYQSVYNWQYVHCLFLWCRVLSTAGPSEALQPLVYPLAQVIIGCIKLIPTARFYPLRMHCIRALTLLSGSSGAFIPVLPFILEMFQQVDFNRKPGRMSSKPINFSVILKLSNVNLQEKAYRDGLVEQLYDLTLEYLHSQAHCIGFPELVLPVVLQLKSFLRECKVANYCRQVQQLLGKVQENSAYICSRRQRVSFGVSEQQAVEAWEKLTREEGTPLTLYYSHWRKLRDREIQLEISGKERLEDLNFPEIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILR-PLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDAEAGLAPG-----ELQQLAQGPEDELEDLQLSEDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WV70-1", "uniprot_id": "NOC2L_MOUSE", "id": "Q9WV70-1", "name": "Nucleolar complex protein 2 homolog", "aln": "MAASRAPRRRLEDLSVDEFLASGFESGSESELEG--AAEERRARGAAWNRERRGARTSPGPAGRLRKGRASEHKDQLSRLKDRDPEFYKFLQENDRSLLDFSDSDSSAEEEEP----FHSLPDTLEEASETEE--DGGEDSDALPRGLRSKKNE--PVPVTLAMVERWRQGSRHHLTPRLFHEVVQAFRAAVATTQGEQEAAETCRFQVADSAVFNALVTFCIRDLCGCLQKLLFGKTP-KDSNRLLLPSSSPLWGKLRVDVKSYLSAVVQLAACLAEATVSAAVLQHISSLVPYFLTFPKQCRMLLKRMVVLWSTGEESLRVLAFLVLIRVCRHKKEAFLGPILKQMYIMYVRNCKFTSPSTLPLISFMQRTLTEMLALDPSVSYQHAFLYIRQLAVHLRNAMTTGKKETHQSVYNWQYVHCLYLWCRVLSTLGSSEILQPLLYPLSQIIIGCIKLLPTARFYPLRMHCVRALTLLSQTIGTFIPVLPFILEIFQQVDFNRRPGRMSSKPINFSVILKLSSTNLQEKAYRDGLLEQLCDLILEYLHSQAHSIAFPELVLPTVLQLKSFLRECKVANYCRQVRQLLEKVQENARHIESLRQSATFSVSDRTAVDAWEKQVREEGTPLTRYYGHWKKLRDREIQLEISGKERLEDLNFPEIKRRKVEDRKDEDRKELKDLFELDSSEGEDSTDFFERGVPR-LPEAHQGLKEDQE-EEDKEEGDSDSEDGDTDTGVDLS-------ELWQLAQGAQDELEDLQLSEED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QFC4-1", "uniprot_id": "F1QFC4_DANRE", "id": "F1QFC4-1", "name": "", "aln": "--MAGKNKRKLEDLSVDEFMLSGFDSDEEDDCED---EEPSPKKGKSKTPALQKT-------SVKKHGKASEHKDQLSALKTKDPEFYKFLEQNDQELLNFDDTDSDEEEEDEEEQMYHKLPSQLEEDDDDDDEEEEEDEEDSKKKDVKKQKSSKEGTKVTEAMIENWKTALKKEPTPTLIRDITQAFKAAVATTKGDSD--ELCRYVISDSAVFNSLVLFCIRDMHAALQKMLKLKTPDKDTKKLVLPFSSTRWQKNQIDIKMYLAGVVQLLSSLTQATVIAAVLRHANQMVPYYLCLPKQCRQFLKSLIKHWSTGEETVRVLAFLALNKICRHKPDAHLSAVLKQMYIAYVQNCKFTSPNTLPMINFMQRTLAEMYSLDTQVSYQHTFLYIRQLAIHLRNAMNLKKKETYQSVYNWQYVHCLYLWCRVLSTIYPSEVLEPLIYPLCQVIIGCIKLVPISRYYPLRLHCVRAIILLSGNTKTFVPALPFLLEILQQEDFNKKPGRMSVKPINFAVILKLSKFNLQEKAYKDGLVEQLYDLILECFHTQACSIGFPELALPTIIQLKAFLKECKVANYCKQMRQLLEKIQENCSHITGRRQKAAFGVADVTAVAAWEKLVAEEGTPLTKYYSQWKKLREKEIQLEISGKERMEDLNLPEIKRKKAEEKK-ADKKEFKGLFESDSDDDDDDNLFQSKEEKDDSDEDDEGLEDLTDLSDEDNEDDSDGDQKQPSSSKGKAPKKMLSTELKQVAEGDEDMVEDLELSDQD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*:* :*:****: ***:* .*.: *. * : : . . ::*:********* ** :********::**:.**:*.*:**. *** :*.**. *** .: :: : :: * :.:: :*. . ** **:*.*: . ::. ** *::::.***:******:*:.: * :: ::***.**:** *****: ..***:* *.. **:.::: * **. * * ::*:* **...:** :.*:::** ****:* . :** :* :***** :** :: ******::******.* ::**** ::.*..:****** **:*******.:**:*.*** **:*: :*:. *:***:********:******. ****:************:******** .** *:**:***.*:*******:* :*:****:**:**: *** . :*:*.***:**::** ***::***** *****:******. *******:***:*** ** ** :*:** .*.****.**.::***:**:********:*::*** *:***. :* . ** .:*.*:: ** **** . ******* **.:*:***::***********:****:*****:* ::* *:*::*.**: :*.: :* * .: . .*::: : .:: :*..*:.:: :..: . : ** *:*:* :* :***:**::*", "identical_positions": 380, "similar_positions": 223, "identity": "49.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000607-77", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5YBN1-1", "uniprot_id": "A0A8I5YBN1_RAT", "id": "A0A8I5YBN1-1", "name": "", "aln": "--------------------------------------------------------------------MEESEGQKCEPNLPP--------SADSRQMPQQGKSNLHVTSQEDAACRRPKERLSNGNTRAQ--VSKPARN-IPRRHTLGGPRSSKEILGMQTSEMDRKREAFLEHLKQKYPHHATAIMGHQERLRDQTKSPK--LSHSPQPPNLGDPVEHLSETSGDSLEAMSEGDVPSPFARGSRTRASLPVVRSTNQTKERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDESRNVYYELNDVRNIQDRSLLKVYNKDPSHAFNHMAKAVNGDVRMQREIVYARGDGLVAPRPGSTAHPPHVIPNSPPSTPVPHSLPPSPSRIPYGGS-RPMAIPGNATIPRDRLS-SLPV-SRSISPSPSAILERRDVKPDEDMSSKNLVM-FRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDHVIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKPRKYPDSHLPALGSKTPPASPHRVGDLRMIDMHPQLNVHGPPHTLQPDRASPSRQSFKKESGTLVYIEKPRNTPGLSGLVDLGPPLVEKQVFAYSTATIPKDRETRERMQAMEKQIASLTGLVQSALFKGPITSSSKEASSEKMMKATANRNQAEGAGAA-HVSAGKSLGAVESSLPPSQPLPAGTSPIHTSLLDMRRNVAELRLQLQQMRQLQLQNQEILRAMMKKAELEISSKVKETMKRLEDPVQRQ-RTLVEQERQKYLHEEERIVKKLRELEDFVEDLKKDS--SSAGRVVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMRAVLRIEVEAVR----FLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYVAMEKATAAEVLKHQEETTHAPGQPLHCSTGSPGDVKSEVVPLSTMTVHHVQSSPVVMQPSQHSSALTNPAQNLPGGTRPHTAIS---QEVISSPQSAPAPQSPQTPLNGSSVQSLFIEEIHSVSAKN--RAVSIEKAERKWEEKRQNLEHYNGKEFEKLLEEAQVNIMKSIPNLEMP---------PTSSPVAKGDGTAVDK-----LELSEDSPNSEQELDKLGGKSP---------------------------------------------PPPPPPPRRSYLPGSGLTTTRSGDVIYTGRKE-SMSKVTSEEPGPTPQTRATKCPPEEPAPACVPSPPPVPASSSKDGEEEEE-GDKIMAELQAFQRCSFTDVNPNSHAEQSRADSHLKDTRPGATAPPKEKKNLEFFHEDVRKSDVECENGPQAESQKVTAGALRPSGPPKWGRAMVDSLSDTSRTSECRADTFTEEIA-PNKNLYQDGRNYSQKNVPKVSFN-FTGLNSLEGDINKGSKVSGLQYAGPDTENQ----KLNFGKIKEIVQHGQENADKGQIPPPTQSAEFSVHDVKTQDQDVPVADYGQVVLRSKVGRHTNMNMNEDGESTPSSPSEE--HTATDNIAFMITKTAVQVLSSGEVHDIVSQKGQDVQTVNIDGRKETASQQ-------EGTEGEEPVVCLDKKPVIIIFDEPMDIRSAYKRLSTIFEECDEELERMLTEEKIEEEEEDENGD-----QTSSQMSHEQVNSGSGRIGQKAETQSQPHIRSAESLTPGEQEVHKAEQRKLSSADSPDSGNR-CEVADDQFESPKKKFKFKFPKKQLAALTQAIRTGTKTGKKTLQVVVYEEEEE-DGTLKQHKEAKRFEITRSQPEDALKTMARRQEQLSLEGTFPTSRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPRTLVDTPCSSNRDC--------------GASLPHITQEVSPRS---LLVLDEVPPAPEPPTSISS--------ASRKGSSTTPQTSRMPVPMTSKNRPGS----LDKASKPSKLQDP-RQYRQANGSAKKAGGDCKPTSPSLPASKIPALSPSSGKSSSLPSASGDSSNLPSAPATKSSIASTPLSPQAGRSVHSASLIPSVSNGSFKFQSPPHAGKG-HHLSFALQAQNGRAAPTSSSSSSPPSPASPTSLNQGARGIRTIHTPSLASY-KAQNGGSSK---ATPSTAKETS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AQ25-1", "uniprot_id": "SKT_MOUSE", "id": "A2AQ25-1", "name": "Sickle tail protein", "aln": "--------------------------------------------------------------------MEESEGQKCEPNLPP--------SGDSRQMPQQGRSNLHVTSQEDAACRRPRERLSNGNARAQ--VSKPARN-IPRRHTLGGPRSSKEILGMQPSEMDRKREAFLEHLKQKYPHHATAIMGHQERLRDQTKSPK--LSHSPQPPNLGDPVEHLSETSGDSLEAMSEGEVPSPFARGSRTRASLPVVRSANQTKERSLGVLYLQYGDETKQLRMPNEVTSTDTIRALFVSAFPQQLTMKMLESPSVAIYIKDDSRNVYYELNDVRNIQDRSLLKVYNKDPSHAFNHMTKAVNGDMRMQREIVYARGDGLVAPRPGSVAHPPHVIPNSPPSTPVPHSLPPSPSRIPYGGS-RPMAIPGNATIPRDRLS-SLPV-SRSISPSPSAILERRDVKPDEDMSSKNLVM-FRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDHVIAYHRTAIRSASAYCSPSLQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVGDLRMIDLHPHLNTHGPPHTLQPDRASPSRQSFKKEPGTLVYIEKPRNTSGLSSLVDLGPPLVEKQGFAYSTTTIPKDRETRERMQAMEKQIASLTGLVQSALFKGPITSSSKEASSEKMVKATANRNQADGAGTA-HVSAGKVLGSVEFSLPPSQPLPAGTSPIHTSLLDMRRNVAELRLQLQQMRQLQLQNQEILRAMMKKAELEISNKVKETMKRLEDPVQRQ-RTLVEQERQKYLHEEERIVKKLCELEDFVEDLKKDS--SSTGRVVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMRAVLRIEVEAVR----FLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTDASQAAQYVAMEKATAAEVLKHQEETAHAPGQPLHCSTGSPGDVKSEVVPLSTMTVHHVQSSPVVMQPSQHSSALMNPAQNLPGGTRPHTASPPAITQEVTSAQSAPGPQSPQTPVNGSSMQSLFIEEIHSVSAKN--RAVSIEKAEKKWEEKRQNLEHYNGKEFEKLLEEAQANIMKSIPNLEMP---------PASSPVSKGD-AAGDK-----LELSEDSPNSEQELDKIGGKSP---------------------------------------------PPPPPPPRRSYLPGSGLTTTRSGDVVYTGR---SMSKVSSEDPGPTPQTRATKCPPEEPASAWAPSPPPVPAPSSKEEEEEEEEGDKIMAELQAFQKCSFMDVNPNSHAEQSRANSHLKDTRAGATAPPKEKKNLEFYHEDVRKSDVECENGPQVESQKVTAGALRPSGPPKWERVMVDSISDTSRTSECRADTFTEENATPNKSLFRDSRNYSQKNVPKVSFS-SSGLNSLEGEINKGPNVSGLQCAIPDLENQ----KLNFGKTKEIGQQGQENADKSHIPLPTRSAEFSIHDVKTQDQDVPVTGYGQVVLRSKVGRHANMNMNEDGESTPSSPSEE--HTATDNIAFMITKTAVQVLSSGEVHDIVSQKGQDVQTVNIDGRKETASQH-------EGTEGEEPVVCLDKKPVIIIFDEPMDIRSAYKRLSTIFEECDEELERMLTEEKIEEEEEDENEDSGV--RTSSQMSCEQVDSRSDRMGQKAETQSQPHVLSAELLTPGVQGVRKAEQRKLSSADSPDSGNK-CGMVDDQFESPKKKFKFKFPKKQLAALTQAIRTGTKTGKKTLQVVVYEEEEE-DGTLKQHKEAKRFEITRSQPEDALKTMARRQEQLSPEGTLPASRTDEIRKSTYRTLDSLEQTIKQLENTISEMSPRALVDTSCSSNRDC--------------GASLPHMAQEVSPRS---LLVLDEVPPAPEPPTSISP--------ASRKGSSTTPQTSRMPVPMTSKNRPGS----LDKASKQSKLQDP-RQYRQANGSAKKAGGDCKPTSPSLPASKIPALSPSSGKSSSLPSASGDSSNLPNAPATKPSIASTPLSPQAGRSAHSASLIPSVSNGSLKFQSPPHAGKGHHHLSFALQTQNGRAAPTTSSSSSPPSPASPTSLNQGARGIRTIHTPSLASY-KAQNGSSSK---ATPSTAKETS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T5P2-1", "uniprot_id": "SKT_HUMAN", "id": "Q5T5P2-1", "name": "Sickle tail protein homolog", "aln": "--------------------------------------------------------------------MEENESQKCEPCLPY--------SADRRQMQEQGKGNLHVTSPEDAECRRTKERLSNGNSRGS--VSKSSRN-IPRRHTLGGPRSSKEILGMQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQTRSPK--LSHSPQPPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTKERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDESRNVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGT-RSMVVPGNATIPRDRIS-SLPV-SRPISPSPSAILERRDVKPDEDMSGKNIAM-YRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDHIIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSDLRMIDMHAHYNAHGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPLMEKQVFAYSTATIPKDRETRERMQAMEKQIASLTGLVQSALFKGPITSYSKDASSEKMMKTTANRNHTDSAGTP-HVSGGKMLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQLQQMRQLQLQNQELLRAMMKKAELEISGKVMETMKRLEDPVQRQ-RVLVEQERQKYLHEEEKIVKKLCELEDFVEDLKKDS--TAASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMRAILRIEVEAVR----FLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAMEKATAAEVLKSQEEAAHTSGQPFHS-TGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNLP-HVASSPAVP---QEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKN--RAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMP---------PATGPLPRGD-APVDK-----VELSEDSPNSEQDLEKLGGKSP---------------------------------------------PPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQAFQKCSFMDVNSNSHAEPSRADSHVKDTRSGATVPPKEKKNLEFFHEDVRKSDVEYENGPQMEFQKVTTGAVRPSDPPKWERGMENSISDASRTSEYKTEIIMKENSISNMSLLRDSRNYSQETVPKASFG-FSGISPLEDEINKGSKISGLQYSIPDTENQ----TLNYGKTKEMEKQ---NTDKCHVSSHTRLTESSVHDFKTEDQEVITTDFGQVVLRPKEARHANVNPNEDGESSSSSPTEE--NAATDNIAFMITETTVQVLSSGEVHDIVSQKGEDIQTVNIDARKEMTPRQ-------EGTDNEDPVVCLDKKPVIIIFDEPMDIRSAYKRLSTIFEECDEELERMMMEEKIEEEEEEENGDSVVQNNNTSQMSHKKVAPGNLRTGQQVETKSQPHSLATETRNPGGQEMNRTELNKFSHVDSPNSECKGEDATDDQFESPKKKFKFKFPKKQLAALTQAIRTGTKTGKKTLQVVVYEEEEE-DGTLKQHKEAKRFEIARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKNTYRTLDSLEQTIKQLENTISEMSPKALVDTSCSSNRDS--------------VASSSHIAQEASPRP---LLVPDEGPTALEPPTSIPS--------ASRKGSSGAPQTSRMPVPMSAKNRPGT----LDKPGKQSKLQDP-RQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKG-HHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSY-KAQNGSSSK---ATPSTAKETS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B9S0-1", "uniprot_id": "A0A8M2B9S0_DANRE", "id": "A0A8M2B9S0-1", "name": "", "aln": "MSKPSRLARPSSAGPKLSSSRRDTPGGKPRMPVVEEKVMRIGSEGSIVGHRPPVNGTTHSQILQSAHLKEEDEASQSKSRISPPKGSTTNVSQQQVTQPKPLKGNLKVTSSEDSEHLTRKQQVVSANSSGNRCEAKSSRAGVPRRHTVGGARSSREILAMQPSDMDKKREAFLEHLKQKYPHHASAIMGHQERLREQTRGSKQSVGCPSPVPVFVDQVEHGSLVSLDALEVMSECDMPLAFTRGSRSRASLPVVRSTNQTKDRSLGVLYLQYGDDTKQIRMPNEITSVDTIRALFVSAFPHQLNMKMLESPSTAIYVKDETRNVYYELTDVRSITDHSCLKVYHKDPAHAFSHGPRPSNGDTRVHREMIFAGRDGHPLRNPPMGPPPPHMQGSMSPTT--PHGMPPSPSRIPFGPR-NPG--GGVATMPRERAGHTLPAPARASSPCPSAILERRDVKPDEDVAAKTMSLNTRAESHYADPYML---------LHHAPPPDTVDH--AYHRATMR---SYSNPSVPLEP--PDHLFRQKSR---NSQLPMLGSKTPPPSPHRMGEMRMVDIHTVQ----PQSSMTLERASPVRQSFRKEAPPMDAMVKARGGMGSPATPDLQ---------VHNPLAPPTDPQTRERMKAMEEQIASLTGLVQHALLKSNSTNSNKEHSSERPVKSGSPAHSTSSTGGS-PVLAPKVVAAPPERSPAPTP-PLGPAPLHVNLHLFRKNVSELRLQLQHMRQLQLQNQECVRAQIKRAEQEIGVKLAEMLRRQDDPTQKQ-RMLVEEERHRYLSMQERVLTQLGDLEQFVETLRTDSGPAASQRAVTLKEVEDGAVSLRKVGENLAGLKGEFPALQSRMRSVLRVEVEAVK----FLKEEPHKLDSMLKRVRTLTDTLSNLRRCATDNLLKPTDQVCSTPPASEK----PELIESPEPAPVTP---------QSSIVRSEVMTSNPVVIHHAQASPVASQQSQQSTAPS-PIPTQRRESTPSPTKQLRKPSLEQTQNNTSNGVSANGVHGKGPSPNLIIEEIHASHSKNKNRAVSIEAAEKEWEEKRQNLGHYDGQEFERILQEAEANMLRGIPNLEVPSQLEGSPAPPAMLPASLEEVVEINEPVAAPREHDDNQPNSEKPAKTASEKPPKPLEKPVKPALEKPLKPSLSIKSNLERQSKTQEKVKLQSTEKTNKSPPPPPPRRNYTTNTGMTTTRSGEVIYTSRKE-SVTEGEEESNISTMSQPEPKTPPEVKPKPITP--PPISASAITE---EEDEGDKIMAELQVFQKCSVKEVGLKGLVEP-----QIRELRPGVLLPLKDKKNTENQDDKNTDTDENGNNTIRQSPGVIYYVTAQISKGTPPPSEESTERRDASQSFPSQVSQINASDQSQSQQQVSNNKSDALKNIGLANFSGTQQQNQLSRSASLKLHPASSWEEVPGSPTQGKVHVVKAAQVQVSIEERVESPTAVCSPVSFGDSEPILSKVIPVETALTNQKLPFGSSKVKERKFEQMEENNEAFLSPDLSGEEPPPPPPDNFAFMITNTKVQALSTGEYHQLVNAKKGSVQTVTFGNKQPSASYSGMASGGDANTNGPPGADNTSKKPVIIIFDEPMDIRSAYKRLSTVF-ECEEELDRMLAEERIDEESEE--------------TEEEEWTRGEKVKQNGVERQSVKRTLADVTDG----EVKNSSSSLLVAGDAK--------------QDGKKKFKLKFPKKQLAALTQAIRAGSKTGKKTLQVVVYEDEEESDGTVKQHKETKRYEIASSKTESSKSNTQESN-----------GRTDEIRKSTYKTLDSLEQTIKQLENTICEMGPTSSEDTESLTNSETQENKVVENSGHSEKGLSSKTLVPRLSAASKGPSLRKKTKPQLLPRPTNIPTTGVSVTPVATHQNANVVSPTSRMPVPVSVKARQPSSTSEKERATKPQKLQDSQRQFRQANGSAKRSGGDPKSTSPTVPASKIPAFSTSTGKSLSQSDSTNNVNSSSPLSSSLPTSKSSIPPPRS--SSIPSSHIPSISNGSLKYAPPTHSTKG---LSIPTQTQNGRPS-TSSSSSCSHSPLSPTMLSQSAKSIRTIHTPSFNSYSRPHNGSAGKSAIPTVTVAKDAA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KW14-1", "uniprot_id": "CCDCX_DROME", "id": "Q7KW14-1", "name": "Coiled-coil domain-containing protein CG32809", "aln": "-------------------------------------------------------------------MLIRWKSKDKSASSNQ--------SVGGSSSSSSKKKRKGREGEEDWQNEAKSGRLPSNEQGGDE-RRRAMRRDDPRRHTLGG-------------------DMLVYGSQHPHAHQMAPQQQRAMDLEMSTRAQK---NKKNQPMRGYAPVNQGPLFDDDPGIMSEVETASTGFRRGGKQRSSLPVVRTPSKTLERPLGLVFLQYRSETKRALLPNEITSIDTVRALFVRSFPRQLTMSYLEGPNVKIYIHDASKDMFYELEDVR----SHLREIRDRSVLRLFESTEVAAP-------PQILPGGPGIPQPLPQAQANWDQDQSYFSEPEFDSDYKHQHIHKSKIGKQPAPYYVGSSQTLPRGMYS-----------------SERNKVSMDGYTSSPERSS----RGNYEEPYYSQYG----------------------TRGAVVAPIIDEEQSDGTMTEDQYALYGIKVGPGPNRLTHRGNQIYDPTRPEDLHRIRVEHMERQLANLTGLVQKALVNQNPQIAPLAVPTLDPNYLVVPSQMQANGSGDELY----------IREKAPKLGKNSCQKSVSFEKSVSFSDDIQGIPKSHNPLHAAETKPTKPAIKSSTLPRTSSQERDRLKPPPPPKPIVLAQTAHPNYRADIALAPEVYNHLRGLQKKAKDLRMEVRTLRRLSQAQAVAVREDIKGTFMRIRATLLASSGSFWDHQGDQDATRISREEELYKQEVIRLEKDLSDLEGSVENLRGEV--INRRTRVNMTAVEDMALVLSRASKTVAELKLKFPSLSNGLRCILSNEMEKVVREEKFLKEEPDRLESALRRCKKLTGTLVTLKR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LASVQEQRLP---------------------------------PNEPTISEETPRSADISAPD--------------------------------------------KPIPTPRMGSFALSGGLAP--------------------------------------------------------------ENALDALLDELKTFSKPIAQQQQQQQQQQQ-----------------QQQQQHQHQQLYEIRPEDSASDESAQAAVQSTVTTQISQARLYTEASVNVQQATTGSMVIAVASGTVSAQAQAQRGVLTHQQSQSQAQLMVHTNMG------SLRRLHSYPSESDGELPGPPPTGPR---------------------ASETSSSTSLANGGSSSKPPVPERNAELITKVGHKRIPPPPPPRTSSRSPLASPTSPNVPPNQ--------------------AAAATVNLIPNSNSNASANANANANSNATGNK--------GIVGETTSVVSG-----------------------------------------------------------------DTSSGDNSSGNESGN-----------------------------------------------DHVQRQVALEMRHQELLKKQKMLQEQYQR-------------------LQQMSKLPSVDVASSSSSS-------------------------------------AQDIASGSNTLRKLG-------------------------------SETNIQQKIAALS-----------------------------LACETSGAAAAAAAAAAAAATNGGVVAS----------------------DATSGAIGGGGGAGAAG---AAGASAAAAHSNSNSNSNLNLNLNSQHQTATTTTKQLYETEIL------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :... .. * . : . . ** :: . : .. :. * *****:** : :: :: :.*: :. : *. .*:. * . *:: . . *. . . * **.: *:******:..:* :*.**:::*** .:**: :***:** **:***** :**:**.*. **.*.. **::* :::::*** *** :: .:. : *. . : . * * . : . . .. : * . . *:** . **..*. * :. .. * :** * :: . * *: * : .. *. *. : :*: .:. . .* .: . : . . . :* : . :: :: ::*:.:: .: . :. ... :. .: :. . * : * . .. :: * :::.. :**:::: :*:*. : :* :* : .* .: * * :..*.. * :: ..* :** ** *: : *.:. *** *. * :..: :* ** :**:*.. :*.:* *:* * ******.:*:* *:* :.:*..* *:* : .: : .:* :: . **: . . ..* * *.* .: . *::. *: * :: **:.*.: : : : ::::: . . * :: : : . * . . : . : : ..:. * . . . * : . . . . . . :.. . :: ::. : : . : ... . .. : . . . . . : : :::. ::: :::* : :: : ::* .: ::: *.... * * . .**: ::. * : . :. . * . .. .. :: ... : : :*...* .**. .:. .*. .* : *..:* * . . : . . .:: : ", "identical_positions": 175, "similar_positions": 384, "identity": "8.12%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000607-82", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DBH0-1", "uniprot_id": "WWP2_MOUSE", "id": "Q9DBH0-1", "name": "NEDD4-like E3 ubiquitin-protein ligase WWP2", "aln": "MASASSSRAGVALPFEKSQLTLKVVSAKP---KVHNRQPRINSYVEVAVDGLPSETKKTGKRIGSSELLWNEIIVLNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENTQLTLNLQTENKGSVVSGGELTIFLDGPTVDLGSVPNGSAVTDGSQPPSRESSGTAIAPETRHQPPSTNCFGGRSRTHRHSGGSARTATAASEQSPGARNRHRQPVKNSSSSGLANGTVNEEPTPASEPEESSVVGVTSLPAAALSVSSNPNTTSLPAQSTPAEGEEASTSGTQQLPAAAQAPDALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQRPTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRVYYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFESGTKQG-SPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELFFIQDMEILGKVTTHELKEGGENIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKNAIYRHYTKSSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDRVGKETWLPRSHTCFNRLDLPPYKSYEQLKEKLLYAIEETEGFGQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00308-1", "uniprot_id": "WWP2_HUMAN", "id": "O00308-1", "name": "NEDD4-like E3 ubiquitin-protein ligase WWP2", "aln": "MASASSSRAGVALPFEKSQLTLKVVSAKP---KVHNRQPRINSYVEVAVDGLPSETKKTGKRIGSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENMQLTLNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQPPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPTTATDPEEPSVVGVTSPPAAPLSVTPNPNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPDALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQRPTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRVYYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFESGTKQG-SPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFNRLDLPPYKSYEQLREKLLYAIEETEGFGQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6P346-1", "uniprot_id": "F6P346_DANRE", "id": "F6P346-1", "name": "E3 ubiquitin-protein ligase", "aln": "MAAASVSQSASIQAIEKSQLTLKVLSAKPQSPKLPNRHSRLSSFVEVTADGLSSETKKTGKRSGHLELQWNEDLTLNVTPQSRLDLKVWSCHTLRKELLGSATIDLLDTLRTHDGKMENVQLSLVLQTENKGSVVAGGELNVCLDGLVVDLGSLPNGSAASDKIHS-SRSSLHRAHSEETPSTSSPRGRSLGQSSRGSCGDSPAEIQGAALTNGDVNGALAETTSRHNSKTTVNNLSSAGKGETAANGLESAHLTCPAPSSPSLSSNPPDGTVPPPAAEPPASTEQSDTT------SDTQNTDALPAGWEQRILPHGRVYYVDHNTKTTTWERPLPPGWEKRVDQRGRFYYVDHNTRTTTWQRPTAESVRNYEQWQSQRSQLQGAMQQFNQRYLYQPSGAVVENDPLGALPPGWEKRQDNGRVYYVNHNTRTTQWEDPRTQGMIQEPPLPPGWEMKYTAEGVRYFVDHNSRTTTFKDPRPGFESGSRQGGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKKPTLKDLESIDPEFYNSIMWVKENDLEECGVELYFAQDMEILGKVTTHQLKDDGENELVTQDNKEEYIGLLTDWRFTRGVEEQTKAFLDGFNEVVPLEWLRYFDEKELELMLCGMQEIDLNDWQKNTIYRHYTKNSKQIHWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFNRLDLPPYKNLEQLREKLLFAIEETEGFGQE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:** *::. .:*********:**** *: **:.*:.*:***:.***.********* * ** *** : ****.**:************:****:*:::* :.*:.:.***** **:* **********:****.: *** .****.:***** :* : **.* * : *. ... . *:* ....*. *: :. . . ::.. : : * : : .*:: *.: : .: .:..** .. .*.. ** .**. *:..*: : :* .********** **:**************************.* ********************** ***********.*******:*.**:***.*.* .::****.**************************************.**********:**********:***************::** *******************************************************************************************************************************************************:*****************:*:***:*****:**:* ************:**:.**. **::****** *************************.************************:.****.:*******.****:***********************************************:***********************. ***:****:***********", "identical_positions": 648, "similar_positions": 131, "identity": "74.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000616-11", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHN8-1", "uniprot_id": "WHR1_MOUSE", "id": "Q9JHN8-1", "name": "Winged helix repair factor 1", "aln": "MNRKRRLLASEAFGVKRRRAPGPVRADPLRTRAGSAREAIEELVKLFPRGLFEDALPPIALRSQVYSLVPDRTVADLQLKELQELGEIRIIQLGFDLDAHGIVFTEDYRTRVLKACDGRPCAGAVQKFLASVLPACGDLSFQQDQMTQTYGFRDPEITQLVNAGVLTVRDAGSWWLAVPGAGRFIKCFVKGRQAVLSMVRKAKYRELALSELLGRRAPLAVRLGLAYHVHDLIGAQLVDCVPTTSGTLLRLPDT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49842-4", "uniprot_id": "WHR1_HUMAN", "id": "P49842-4", "name": "Winged helix repair factor 1", "aln": "MSWKRHHLIPETFGVKRRRKRGPVESDPLRGEPGSARAAVSELMQLFPRGLFEDALPPIVLRSQVYSLVPDRTVADRQLKELQEQGEIRIVQLGFDLDAHGIIFTEDYRTRVLKACDGRPYAGAVQKFLASVLPACGDLSFQQDQMTQTFGFRDSEITHLVNAGVLTVRDAGSWWLAVPGAGRFIKYFVKGRQAVLSMVRKAKYRELLLSELLGRRAPVVVRLGLTYHVHDLIGAQLVDCISTTSGTLLRLPET--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IK86-1", "uniprot_id": "A0A0R4IK86_DANRE", "id": "A0A0R4IK86-1", "name": "", "aln": "MSRKR-ALIADTFCLKRRRCAADSLTGETHDGATDIRSSIQYLMTLFSRKLFNDTLPPVVLKHQLYSLHTDKTSVDKHVNDLRENGELLMFQLGFDSEAFALVFAEDYRAKVLQEEAGRKTLGTAEKFLDKLIPGCSDLSFNKDKMLKEFLFSDSEITQLVKSGLLTVRDAGSWWLSIPNSGRFIKYFIKGRKAVLNMVKKSKYSEILRTELEERRTTAQVKFQMKYHVHDIIGADLVECIQTTSGTVLRYVDGNN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. ** * .::* :**** . :. : . . * ::. *: **.* **:*:***:.*: *:*** .*:* .* ::::*:* **: :.***** :*..::*:****::**: ** *:.:*** .::*.*.****::*:* : : * *.***:**::*:***********::*.:***** *:***:***.**:*:** *: :** **:. *:: : *****:***:**:*: *****:** : ", "identical_positions": 120, "similar_positions": 82, "identity": "46.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000616-15", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7Y6-1", "uniprot_id": "G3V7Y6_RAT", "id": "G3V7Y6-1", "name": "Forkhead box protein H1", "aln": "-----------------------------------------------------MASGWDLASTYSPTTLSPQLVQALAQGYIPCMGPLDNSQLRPPEAES------LSKTPKRRKKRYLRHDK-PPYTYLAMIALVIQ--------AAPFRRLKLAQIIRQVQAVFPFFRDDYEGWKDSIRHNLSSNRCFRKVPKDPAKPQAKGNFWAVDVSLIPAEALRLQNTALCRRWQNRGTHRAFAKDLSPYVLHG-------QPYRPPS--PPPPSREDFSIKSLLGDPGKASTWPQHPRLAGQSTPAQASTLSKGEE--GIGAGPSNVSDKPLWPLSSLPRPTRIEGETSQGEVIRPSPVS--------SDQGSWPLHLLQDSSDSMGMSRRGSRASLWGQLPTSYLPIYTP------------NVVMPLATLPPTSCP----RCPSSASPAYWSVGTE---SQGSQDLLCDLDSLFQGVPPNKSIYDVWVSHPRDLAAPAPGWLLS------WYSM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88621-1", "uniprot_id": "FOXH1_MOUSE", "id": "O88621-1", "name": "Forkhead box protein H1", "aln": "-----------------------------------------------------MASGWDLASTYTPTTPSPQLALAPAQGYLPCMGPRDNSQLRPPEAES------LSKTPKRRKKRYLRHDK-PPYTYLAMIALVIQ--------AAPFRRLKLAQIIRQVQAVFPFFRDDYEGWKDSIRHNLSSNRCFHKVPKDPAKPQAKGNFWAVDVSLIPAEALRLQNTALCRRWQNRGTHRAFAKDLSPYVLHG-------QPYQPPS--PPPPPREGFSIKSLLGDPGKESTWPQHPGLPGQSTAAQAGTLSKGEE--GMGTGPSSSSETPLWPLCSLPGPTIIEGESSQGEVIRPSPVT--------PDQGSWPLHLLEDSADSRGVPRRGSRASLWGQLPTSYLPIYTP------------NVVMPLATLPTTSCP----QCPSSASPAYWSVGTE---SQGSQDLLCDLDSLFQGVPPNKSIYDVWVSHPRDLAAPAPGWLLS------WYSM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75593-1", "uniprot_id": "FOXH1_HUMAN", "id": "O75593-1", "name": "Forkhead box protein H1", "aln": "------------------------------------------------------------------------------------MGPCSGSRLGPPEAES------PSQPPKRRKKRYLRHDK-PPYTYLAMIALVIQ--------AAPSRRLKLAQIIRQVQAVFPFFREDYEGWKDSIRHNLSSNRCFRKVPKDPAKPQAKGNFWAVDVSLIPAEALRLQNTALCRRWQNGGARGAFAKDLGPYVLHG-------RPYRPPS--PPPPPSEGFSIKSLLGGSGEGAPWP---GLAPQSSPVPAGTGNSGEE--AVPTPPLPSSERPLWPLCPLPGPTRVEGETVQGGAIGPSTLS--------PEPRAWPLHLLQGTAVPGGRSSGGHRASLWGQLPTSYLPIYTP------------NVVMPLAP-PPTSCP----QCP-STSPAYWGVAPE---TRGPPGLLCDLDALFQGVPPNKSIYDVWVSHPRDLAAPGPGWLLS------WCSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I9E1-1", "uniprot_id": "FOXH1_DANRE", "id": "Q9I9E1-1", "name": "Forkhead box protein H1", "aln": "---------MTKHWGGPGLLAPPVITVGEG-----------------AQRDHHLDCRIGYSSSKRSCHRSSNPLLELGGRLDKSTGMAQDSCYRAKATNQGPWELQDGNSSGGKKKNYQRYPK-PPYSYLAMIAMVIQ--------NSPEKKLTLSEILKEISTLFPFFKGNYKGWRDSVRHNLSSYDCFVKVLKDPGKPQGKGNFWTVEVNRIPLELLKRQNTAVSRQDE-----TIFAQDLAPYIFQGYSQPNKSKPLPPESSLPPVPTRQSPPPSEDPYRPKLDSTFAIDSLLHSLRPASSAGEGLRERESWGVGPPPHTRSTTPPRPCNASYNGSSSASSVSPASDFSDEDWRGVTVVGKRSGDRGITSDAYSDSCPPPNKSSKRGNTPPW-ELPTSYAKYTPPNAVAPPSMRFNGNPFMPLGGIPFYGYGGAHVTTSHLIGHPYWPILPSGPVSIQAPPLLMDLDSMLQSVPPNKSVFDALGSNNQTVHPSPNQYALQNGPSLCKYSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32030-1", "uniprot_id": "SLP1_DROME", "id": "P32030-1", "name": "Fork head domain transcription factor slp1", "aln": "--MVKSEMEFKSNFSIDAILAKKPINTATQPIKTEPVHHHHQYVHPYSNSDGELSASEDFDSPSRTSTPMSSAAESLSSQNNDKLDVEFDDELEDQLDEDQ--ESEDGNPSKKQKMTAGSDTKKPPYSYNALIMMAIQ--------DSPEQRLTLNGIYQYLINRFPYFKANKRGWQNSIRHNLSLNKCFTKIPRSYDDP-GKGNYWILDPS--AEEVFIGETTGKLRRKN-----------------------------------PGASRTRLAAYRQAIFSP----------MMAASPYGAPASS---------YGYPAVPFAAAAAAALYQRMNPAAYQAAYQQMQYQQAPQAH----------HHQAPHPAQMQGYPQQLNAELFQRMQFFGKFPSS----------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40466-1", "uniprot_id": "FKH1_YEAST", "id": "P40466-1", "name": "Fork head protein homolog 1", "aln": "MSVTSREQKFSGKYSSYTAQDRQGLVNAVTCVLSSSSDPVAVSSDYSNSLSIAREVNAYAKIAGCDWTYYVQKLEVTIGRNTDSLNLNAVPGTVVKKNIDIDLGPAKIVSRKHAAIRFNLESGSWELQIFGRNGAKVNFRRIPTGPDSPPTVLQSGCIIDIGGVQMIFILPEQETIISDYCLNHLMPKLLSTYGTNGNNNPLLRNIIEGSTYLREQRLQEEARLQQLDHLHTPLSSSSDVNPIGDPHGDTIMMEEDEEDENYTRGGIRPNTYTSSSNNAVTNGNVPHIENPSDLSLDENRYIKPPQSYASMIT---QAILSTPEGSISLADIYKFISDNYAFYRFSQMAWQNSVRHN----LSLNKAFEKVPKRAGQQGKGMNWKISDEVRRDFLNKWNAGKLSKIRRG-----------ASVTRQLQLHMSKFGEIPAPESSSIDPRGIKAQKVKKSLQATSSILGESAPQLQRTQLTGQISTTTSMDVTTNANVNNSSLS-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . :: :* * * : :: : . .. * : . . . * . . : . . : . . . . . . : :. ", "identical_positions": 5, "similar_positions": 33, "identity": "0.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000616-16", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P38532-1", "uniprot_id": "HSF1_MOUSE", "id": "P38532-1", "name": "Heat shock factor protein 1", "aln": "MDLA-VGPG--AAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVTSVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHAQQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPYSAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQEPPSPPHSPRVLEASP-------GRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTG-----AQAPALPTPSTPEKCLSVACLDK-----NELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTMPDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTGSSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00613-1", "uniprot_id": "HSF1_HUMAN", "id": "Q00613-1", "name": "Heat shock factor protein 1", "aln": "MDLP-VGPG--AAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVTSVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHAQQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGSGPYSAPSPAYSSSSLYAPDAVASSGPIISDITELAPASPMASPGGSIDERPLSSSPLVRVKEEPPSPPQSPRVEEASP-------GRPSSVDTLLSPTALIDSILRESEPAP-ASVTALTDARGHTDTEGRPPSPPPTSTPEKCLSVACLDK-----NELSDHLDAMDSNLDNLQTMLSSHGFSVDTSALLDLFSPSVTVPDMSLPDLDSSLASIQELLSPQEPPRPPEAENSSPDSGKQLVHYTAQPLFLLDPGSVDTGSNDLPVLFELGEGSYFSEGDGFAEDPTISLLTGSEPPKAKDPTVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6P697-1", "uniprot_id": "F6P697_DANRE", "id": "F6P697-1", "name": "", "aln": "MEYHSVGPGGVVVTGNNVPAFLTKLWTLVEDPDTDPLICWSPNGTSFHVFDQGRFSKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPEKDDTEFQHPYFIRGQEQLLENIKRKVTTVSNIKHEDYKFSTDDVSKMISDVQHMKGKQESMDSKISTLKHENEMLWREVATLRQKHSQQQKVVNKLIQFLITLARSNRVLGVKRKMPLMLNDSSSAHSMPKFSRQYSLESP------APSSTAFTGTGVFSSESPVKTGPIISDITELAQSSPVAT-DEWIEDR---TSPLVHIKEEPSSPAHSPEVEEVCPVEVEVGAGSDLPVDTPLSPTTFINSILQESEPVSALTPPPSEQKCLSVACLDNYPQMSEISRLFSGFSTSSLHLRPHSGTELHDHLESIDSGLENLQQILNAQSINFDSSPLFDIFS-----SAASDVDLDS-LASIQDLLSP-DPVKETES-GVDTDSGKQLVQYTSQPIVLPDPLSTDSSSTDLPMLLELQDDSYFS--SEPTEDPTIALLN--FQPVPEDPKLS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: **** .. .*************.*****.******.*.********:*:****************************************:******** *:***************:**.:* ** *: *.*:::::*** ******.****: ::***** ******:*****:**************:*.:***:******:****.**.****:**:.**:*** :..*.*::.:.:::.:: ..:*********** :**:*: . *::* :*.**::*:**.**.:**.* *..* * .:** ****::*:***:****.. : .. : . * . * . :*.:.*. .** ***:::**.*:*** :*.::.:..*:*.*:*:** . * **** *****:**** :* : *: . ..*******:**:**:.* ** :.*:.*.:**:*:** :.**** . ::****:**. .:**.:*", "identical_positions": 299, "similar_positions": 143, "identity": "54.86%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000616-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R7V1-1", "uniprot_id": "M0R7V1_RAT", "id": "M0R7V1-1", "name": "DNA-binding death effector domain-containing protein 2", "aln": "--GRGGRTCASWAKEEERGDAGVIIEKVPERSKTSGCGRRPEVIGRWNLVVGGQLTECELELLAFLLDEA-----------------PGAPGG----------------------------LARARSGLELLLELERRGQCDESNLRLLSQLLRVLARHDLLPHLARKRRRPVSPERYSYGNSSSSSKRTEDSGRCRRRASSSSHSPQSQWDTGSPPTKRQRRSQGRPSSGARQRRRAGLAASQQQQQQQQEPGRSSSEGKVTCDIRLRVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVLRSRDLGSVVCDIKFSELSYLDAFWGDYLSGALLQALRGVFLTEALREAVGREAVRLLVSVDEADYEAGRRRLLLMEEEEGRRGTEAS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8QZV0-1", "uniprot_id": "DEDD2_MOUSE", "id": "Q8QZV0-1", "name": "DNA-binding death effector domain-containing protein 2", "aln": "-MALSGSTPAPSWEEDECLDYYGMLS-----------------LHRMFEVVGGQLTECELELLAFLLDEA-----------------PGAPGG----------------------------LARARSGLELLLELERRGQCDESNLRLLSQLLRVLARHDLLPHLARKRRRPVSPERYSYGNPSSSSKRTEDSCRRRRQASSSSDSPQSQWDTGSPPTKRQRRSRGRPSSGARQRRRAGLAAS-QQHQQHQELGRPSSEGKVTCDIRLRVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVLRSRDLGSVVCDIKFSELSYLDAFWGDYLSGALLQALRGVFLTEALREAVGREAVRLLVSVDEADYEAGRRRLLLMEEEGGRRGTEAS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WXF8-1", "uniprot_id": "DEDD2_HUMAN", "id": "Q8WXF8-1", "name": "DNA-binding death effector domain-containing protein 2", "aln": "-MALSGSTPAPCWEEDECLDYYGMLS-----------------LHRMFEVVGGQLTECELELLAFLLDEA-----------------PGAAGG----------------------------LARARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYG-TSSSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGRPSGGARRRRRGAPAAP----QQQSEPARPSSEGKVTCDIRLRVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVLRSRDLGSVVCDIKFSELSYLDAFWGDYLSGALLQALRGVFLTEALREAVGREAVRLLVSVDEADYEAGRRRLLLMEEEGGRRPTEAS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YTH0-1", "uniprot_id": "A0A8M6YTH0_DANRE", "id": "A0A8M6YTH0-1", "name": "", "aln": "MSSVKCSRYSLYWEETECLSYYETLS-----------------LHEIFEIVGSQLTETDVEVLSFLLDETYPGKHPLDPEGWTEDLPPGPDGSPQANTPCPRLLKSWQRMQPQKEGCSIASRHRPKSGVELLLELERRGYLSDANLRPLLQLLRILTRHDVLPFVSQKKRRTVSPERQKIDYPEVDFRQDREVG-SNTNIPSFENTQDHHWRAGSGSSMTSASSNRRKRGRGHHWSRKSRGPP--------EIQPQSTPNKVTCDIRLRVRAEYSEHESALRGGVSSDKPQPLERQFELFSRASLLLRTRDLGSIVCDIKFSELTNLDAFWADYLSGALLEALKGVFITDSLKRAAGQEGVRLLVSVDQDDYEEGRK-LLINSQTQNWTNWEAQRP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :* * . :. : . :**.**** ::*:*:*****: **. *. *.:**:********** .::*** * ****:*:***:**.:::*:**.***** . . .. . :: . . . .* .: : :* :** .: . *. * . .:: * . ... * *: .**************.** .**. **:* :**.* **:::*.:*: :**:*****:*********: *****.********:**:***:*::*:.*.*:*.********: *** **: **: .: . **. ", "identical_positions": 146, "similar_positions": 96, "identity": "36.87%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000616-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LKQ1-1", "uniprot_id": "A0ABK0LKQ1_RAT", "id": "A0ABK0LKQ1-1", "name": "", "aln": "MCVQRAVSSGFPGLSASLK-------------------------VQLSLPRDLGAENCLSENNHPDKPLKVLEELGKEFLTEYLEKLVQSNVLKLKEEEKQKFNNAERSDKRWVFVDVLKRKHNQVGKMLLQTFLNVDSGSHHGEANLEMEE------------------------------------------PE--ESVDTLKLCSSEEFTRLCREKKQEIYPIKETNGRTRKALIICNTEFKHLSL-RYGANIDISGMKGLLEELGYDVVVKEELTAEGMESEMKDFAALSEHQTSDSTFLVLMSHGTLQGLCGTMHS--EATPDVLLYDTIYQIFNNCHCPGLRDKPKVIIVQACRGGNPGEVWIRESSGAHSYRAVD--LPRNMEADAVRMSHVEKDFIALYSTTPHHLSYRDKTRGSYFISKLISCFRIHACSCHLFDIFLKVQQSFEKASIN---SQMPTIDRATLTRYFYLFPGN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70343-1", "uniprot_id": "CASP4_MOUSE", "id": "P70343-1", "name": "Caspase-4", "aln": "----------------------------------------------------------MAENKHPDKPLKVLEQLGKEVLTEYLEKLVQSNVLKLKEEDKQKFNNAERSDKRWVFVDAMKKKHSKVGEMLLQTFFSVDPGSHHGEANLEMEE------------------------------------------PE--ESLNTLKLCSPEEFTRLCREKTQEIYPIKEANGRTRKALIICNTEFKHLSL-RYGANFDIIGMKGLLEDLGYDVVVKEELTAEGMESEMKDFAALSEHQTSDSTFLVLMSHGTLHGICGTMHS--EKTPDVLQYDTIYQIFNNCHCPGLRDKPKVIIVQACRGGNSGEMWIRESSKPQLCRGVD--LPRNMEADAVKLSHVEKDFIAFYSTTPHHLSYRDKTGGSYFITRLISCFRKHACSCHLFDIFLKVQQSFEKASIH---SQMPTIDRATLTRYFYLFPGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49662-1", "uniprot_id": "CASP4_HUMAN", "id": "P49662-1", "name": "Caspase-4", "aln": "MAEG----------------------------------------------------------NHRKKPLKVLESLGKDFLTGVLDNLVEQNVLNWKEEEKKKYYDAKTEDKVRVMADSMQEKQRMAGQMLLQTFFNIDQISPNKKAHPNMEAGP----------------------------------------PESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFDHLPP-RNGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGILEGICGTVHD--EKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDSPASLEVASSQ--SSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQKYSWCCHLEEVFRKVQQSFETPRAK---AQMPTIERLSMTRYFYLFPGN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P51878-1", "uniprot_id": "CASP5_HUMAN", "id": "P51878-1", "name": "Caspase-5", "aln": "MAEDSGKKKRRKNFEAMFKGILQSGLDNFVINHMLKNNVAGQTSIQTLVPNTDQKSTSVKKDNHKKKTVKMLEYLGKDVLHGVFNYLAKHDVLTLKEEEKKKYYDTKIEDKALILVDSLR-KNRVAHQMFTQTLLNMDQKITSVKPLLQIEAGP----------------------------------------PESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDHLPA-RNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHK--KKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQ--SSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLMEIFRKVQKSFEVPQAK---AQMPTIERATLTRDFYLFPGN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q920D5-1", "uniprot_id": "CASPC_RAT", "id": "Q920D5-1", "name": "Caspase-12", "aln": "---------------------------------------------------------MAAKRTHERDPIYKIKGLAKDMLDGVFDDLMDKNVLNGDELLKIGEGASLILSKAENLVESFFEKTEMAGKIFAGHIANSDKQLSLQFPSDDEEDELQKMFTPSSASESRGKVEDEEMEVNVGVAHASHLMLTVPQGIQSTEVQDSLKLCSRDWFCTMKTERAEEIYPVMEKEGRTRLALIICNKKFDYLFD-RDDAETDILNMKELLQNLGYSVVIKENLTAQEMETELMKFAGRPEHQSSDSTFLVFMSHGILEGICGVKHR--NKKPDVLHDDTIFTIFNNSNCPSLRNKPKILIMQACRGRHTGTIWVSTSKGIATADTDEECVLSHRWNNSITKAHVETDFIAFKSSTPHNISWKVGKSGSLFISKLIDCFKKYCWCYHLEEIFRKVQYSFEVPGEL---TQMPTIERVSMTRYFYLFPGN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08736-1", "uniprot_id": "CASPC_MOUSE", "id": "O08736-1", "name": "Caspase-12", "aln": "---------------------------------------------------------MAARRTHERDPIYKIKGLAKDMLDGVFDDLVEKNVLNGDELLKIGESASFILNKAENLVENFLEKTDMAGKIFAGHIANSQEQLSLQF-SNDEDDGPQKICTPSSPSESKRKVEDDEMEVNAGLAHESHLMLTAPHGLQSSEVQDTLKLCPRDQFCKIKTERAKEIYPVMEKEGRTRLALIICNKKFDYLFD-RDNADTDILNMQELLENLGYSVVLKENLTAQEMETELMQFAGRPEHQSSDSTFLVFMSHGILEGICGVKHR--NKKPDVLHDDTIFKIFNNSNCRSLRNKPKILIMQACRGRYNGTIWVSTNKGIATADTDEERVLSCKWNNSITKAHVETDFIAFKSSTPHNISWKVGKTGSLFISKLIDCFKKYCWCYHLEEIFRKVQHSFEVPGEL---TQMPTIERVSMTRYFYLFPGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UXS9-1", "uniprot_id": "CASPC_HUMAN", "id": "Q6UXS9-1", "name": "Inactive caspase-12", "aln": "---------------------------------------------------------MADEKPSNGVLVHMVKLLIKTFLDGIFDDLMENNVLNTDEIHLIGKCLKFVVSNAENLVDDITETAQIAGKIFREHLWNSKKQLSSDISSDGERE-----------ANMPG--------------------------------------------------------------------LNIRNKEFNYLHN-RNGSELDLLGMRDLLENLGYSVVIKENLTAQEMETALRQFAAHPEHQSSDSTFLVFMSHSILNGICGTKHW--DQEPDVLHDDTIFEIFNNRNCQSLKDKPKVIIMQACRGNGAGIVWFTTDSGKASADTHGRLLQGNICNDAVTKAHVEKDFIAFKSSTPHNVSWRHETNGSVFISQIIYYFREYSWSHHLEEIFQKVQHSFETPNIL---TQLPTIERLSMTRYFYLFPGN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43527-1", "uniprot_id": "CASP1_RAT", "id": "P43527-1", "name": "Caspase-1", "aln": "----------------------------------------------------------MADKVLRAKRKQFINSVSVGTINGLLDELLEKRVLNQEEMDTIKLANITVMEKARDLCDHVTKKGPRASQMFITYICNEDCYLAEILELQSGPSAETVFVTEDSKGGHPFSSETKEKL--------------NKEGGAFPGPSGSLKFCPLEIAQKLWKENHSEIYPIMKTPTRTRLALIICNTDFQHLSR-RVGADVDLREMKLLLQDLGYTVKVKENLTALEMTKELKEFAACPEHKTSDSTFLVFMSHGLQEGICGITYS--NEVADILKVDTIFQMMNTLKCPSLKDKPKVIIIQACRGEKQGVVLLKDSVGNS-EEGFL--TDAIFEDDGIKKAHIEKDFIAFCSSTPDNVSWRHPVRGSLFIESLIKHMKEYAWSCDLEDIFRKVRFSFEQPDSR---LQMPTTERVTLTKRFYLFPGH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29452-1", "uniprot_id": "CASP1_MOUSE", "id": "P29452-1", "name": "Caspase-1", "aln": "----------------------------------------------------------MADKILRAKRKQFINSVSIGTINGLLDELLEKRVLNQEEMDKIKLANITAMDKARDLCDHVSKKGPQASQIFITYICNEDCYLAGILELQSAPSAETFVATEDSKGGHPSSSETKEEQ--------------NKEDGTFPGLTGTLKFCPLEKAQKLWKENPSEIYPIMNTTTRTRLALIICNTEFQHLSP-RVGAQVDLREMKLLLEDLGYTVKVKENLTALEMVKEVKEFAACPEHKTSDSTFLVFMSHGIQEGICGTTYS--NEVSDILKVDTIFQMMNTLKCPSLKDKPKVIIIQACRGEKQGVVLLKDSVRDS-EEDFL--TDAIFEDDGIKKAHIEKDFIAFCSSTPDNVSWRHPVRGSLFIESLIKHMKEYAWSCDLEDIFRKVRFSFEQPEFR---LQMPTADRVTLTKRFYLFPGH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29466-1", "uniprot_id": "CASP1_HUMAN", "id": "P29466-1", "name": "Caspase-1", "aln": "----------------------------------------------------------MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQD-------------NPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPR-RTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHS--EQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLP--TTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGR---AQMPTTERVTLTRCFYLFPGH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I9L7-1", "uniprot_id": "CASPA_DANRE", "id": "Q9I9L7-1", "name": "Caspase a", "aln": "-----------------------------------------------------------MAKSIKDHLQDALSNIGADNLRRFQSRLGDR-----KQEPRVRKSTIEKLKDEIDLVDLLVNTFTSDAVSVTVDILRGIKCNAVAEELLENTGQGGVSQPEPPVPEPIPK-------------------------DPAQLKELKVTPCSQQFKNKILREKGQETYEIKDKSVRKRLALLINNVDFDDKAMKRSGSEKDEENMEKLLKELDYQVVKRPNLSAKEMDEAIRDFAQREEHKYSDSAFVVIMSHGKRDAIMGVHYHRTNNPSDSFPVDNVYRRLNSENCPALRDKPKVILIQACRGGEHGRVWASDG-----------EPDEPIEIEDDDFVHKEKDFISLMSCTPDTKSYRHVQNGTFYVQTLVDVFIKCAHEDHIEELFRKVLRRFEHPNMIGNFKQMACKDRATLPKLFYLFPGL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . * . .: .. : : . . : * * * .*. * .:. * * **: *.* * . :*:* * : ** **: ***:*:*:***. ..: * : . .* : : :: :*. :* .*::***::::***** * : . : * *.***:: * **. *:: *: :: :: : . .: ::* ** ** . *:. :* ::.: ****** ", "identical_positions": 65, "similar_positions": 78, "identity": "13.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000616-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPV5-1", "uniprot_id": "APAF_RAT", "id": "Q9EPV5-1", "name": "Apoptotic protease-activating factor 1", "aln": "--MDAKARNCLLQHKEALEKDIKTSYIMDHMISNG---VLTVVEEEKVKSQATQYQRAAALIKMILNKDNYAYISFYNALLHEGYKDLAGLLHSGLPLVSSSSGKDTDGGNTSFVRTVLCEGGVPQRPVIFVTRKKLVSAIQQKLWKLNGEPGWVTIYGMAGCGKSVLAAEAVRDHALLEGCFSGGVHWVSIGKQDKS-GLLMKLQNLCTRLGQEES----FSQRLPLNIEEAKDRLR-VLMLRKHPRSLLILDDVWDPWVLKAFDNQCQILLTTRDKSVTDSVMGPKYVIP----VESGLGKEKGLEILSLFVNMKKEDLPVEAHSIIKECKGSPLVVSLVGALLRDFPNRWAYYLRQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCVLWDLETEEVEDILQEFVN--KSLLFCNRNGKSFCYYLHDLQVDFLTEKNRSQLQDLHRKMVTQFQRYHQPHTLSPGQEDCMYWYNFLAYHMASAGMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVCENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDTGRLYLEWINKKTIKNLSRLVVRPHTDAVYHACFSQDGQRIASCGADKTLQVFKAETGE--KLLDIKAHEDEVLCCAFSSDDSYIATCSVDKKVKIWDSGTGKLVHTYE-EHSEQVN-----------------------CCHFTNKSNHLLLATGSNDSFL---KLWDLNQKECRNTMFGHTNSVTHCRFSPDDELLASCSADGTLKLWDVRSAN----EKKSINVK------------------------------------RFFLSSEDPPEDVEVIVKCCSWSADGDRIIVAAKNKVLLLDIHTSG-LLTEIHTGHHSTIQYCDFSPYDHLAVIALSQYCVELWNIDSRVKVADCRGH----LSWVHG---------------------VMFSPDGSSFLTASDDQTIRVWETRK-------VCKNSAIVLKQEIDVVFQENEMMVLAVDNIRGLQLIAGKTGQIDYLPEAQVS---CCCLSPHLEYVAFGDEEGAIKIIELPNNRVFSSGIGHKKAVRHIQFTADGKTLISSSEDSVIQVWNWQTEEYVFLQAHQETVKDFRLLRDS---RLLSWSFDGTVKVWNVITG---RIERDFTCHQGTVLSCAISSDATKFSSTSADKTAKIWSFE---LPSPLHELKGHNSCVRCSAFSLDGILLATGDDNGEIRIWNVSDGQ----------------LLHLCAPISIEEGTATHGGWVTDVCFSPDRKMLVSAGGYLKWWN----VVTGESSQTFYTNGTNLKKIHVSPDFRTYVTVDNLGILYILQVLE-------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88879-1", "uniprot_id": "APAF_MOUSE", "id": "O88879-1", "name": "Apoptotic protease-activating factor 1", "aln": "--MDAKARNCLLQHREALEKDIKTSYIMDHMISNG---VLSVIEEEKVKSQATQYQRAAALIKMILNKDNCAYISFYNALLHEGYKDLAALLQSGLPLVSSSSGKDTDGGITSFVRTVLCEGGVPQRPVIFVTRKKLVHAIQQKLWKLNGEPGWVTIYGMAGCGKSVLAAEAVRDHSLLEGCFSGGVHWVSIGKQDKS-GLLMKLQNLCMRLDQEES----FSQRLPLNIEEAKDRLR-VLMLRKHPRSLLILDDVWDPWVLKAFDNQCQILLTTRDKSVTDSVMGPKHVVP----VESGLGREKGLEILSLFVNMKKEDLPAEAHSIIKECKGSPLVVSLIGALLRDFPNRWAYYLRQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCVLWDLETEEVEDILQEFVN--KSLLFCNRNGKSFCYYLHDLQVDFLTEKNRSQLQDLHRKMVTQFQRYYQPHTLSPDQEDCMYWYNFLAYHMASANMHKELCALMFSLDWIKAKTELVGPAHLIHEFVAYRHILDEKDCAVCENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYRQAKLQAKQEGDTGRLYLEWINKKTIKNLSRLVVRPHTDAVYHACFSQDGQRIASCGADKTLQVFKAETGE--KLLDIKAHEDEVLCCAFSSDDSYIATCSADKKVKIWDSATGKLVHTYD-EHSEQVN-----------------------CCHFTNKSNHLLLATGSNDFFL---KLWDLNQKECRNTMFGHTNSVNHCRFSPDDELLASCSADGTLRLWDVRSAN----ERKSINVK------------------------------------RFFLSSEDPPEDVEVIVKCCSWSADGDKIIVAAKNKVLLFDIHTSG-LLAEIHTGHHSTIQYCDFSPYDHLAVIALSQYCVELWNIDSRLKVADCRGH----LSWVHG---------------------VMFSPDGSSFLTASDDQTIRVWETKK-------VCKNSAIVLKQEIDVVFQENETMVLAVDNIRGLQLIAGKTGQIDYLPEAQVS---CCCLSPHLEYVAFGDEDGAIKIIELPNNRVFSSGVGHKKAVRHIQFTADGKTLISSSEDSVIQVWNWQTGDYVFLQAHQETVKDFRLLQDS---RLLSWSFDGTVKVWNVITG---RIERDFTCHQGTVLSCAISSDATKFSSTSADKTAKIWSFD---LLSPLHELKGHNGCVRCSAFSLDGILLATGDDNGEIRIWNVSDGQ----------------LLHSCAPISVEEGTATHGGWVTDVCFSPDSKTLVSAGGYLKWWN----VATGDSSQTFYTNGTNLKKIHVSPDFRTYVTVDNLGILYILQVLE-------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14727-1", "uniprot_id": "APAF_HUMAN", "id": "O14727-1", "name": "Apoptotic protease-activating factor 1", "aln": "--MDAKARNCLLQHREALEKDIKTSYIMDHMISDG---FLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQDKS-GLLMKLQNLCTRLDQDES----FSQRLPLNIEEAKDRLR-ILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVP----VESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVN--KSLLFCDRNGKSFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDCMYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVSENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINKKNITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGE--KLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYD-EHSEQVN-----------------------CCHFTNSSHHLLLATGSSDCFL---KLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSAN----ERKSINVK------------------------------------QFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSG-LLGEIHTGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGH----LSWVHG---------------------VMFSPDGSSFLTSSDDQTIRLWETKK-------VCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLTEAQVS---CCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQETVKDFRLLKNS---RLLSWSFDGTVKVWNIITG---NKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD---LLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGE----------------LLHLCAPLS-EEGAATHGGWVTDLCFSPDGKMLISAGGYIKWWN----VVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQTLE-------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I9H8-1", "uniprot_id": "APAF_DANRE", "id": "Q9I9H8-1", "name": "Apoptotic protease-activating factor 1", "aln": "--MEERARSRLLRSKATLEQDIKASYLMDHMISDG---VLTNDEEAKVLSKATRKEQAVALLETLLRKDNRAYISFYNALIRESYGDLASLLHSDLPLLSPEGEKSFADGVSPSVQAILSVGGVPQRPVVFVSRPPLLNLIREMLYQLRDTPGWVTVFGMAGSGKSVMAAEVVRDRSLIKECFPDGVHWLSVGQCERA-DLLVRMQSLCFRLEQCQSS--DTSQRPPSTVEEAKERLR-FLMLRRFPRSLLILDDVWDSSSLRSFDIQCRVLLTTRNRALTDSVSGVRYEVP----VENGLDEEKALEILALYVNGKMHKLPEQARSIVSECKGSPLVVSLIGALLREFPDRWSYYLRQLQQKQFKRIRKSSSYDYEALDQAMDASLQVLEAEHQELYRDLSVMQKDIKVPAKVLSVLWGLELEEVEDVLQEFVN--KSLLFRDCNQRPYRYYLHDLQLDFLAEQNRDQIAELHKKMVRQYQRFYSKRPPDSADKDSLYWYQFIPYHMAKAGLSKELYSLMFSLDWVKEKARIMGSAHLINDYVEYGEILDKENSEVRVQFQEFLSLNGHHLEQRPFPDVVQLALSQPDRSEVYRQALMQAQKRASRGQIYLNWVNKNIEEGLSRLVMHPHQGAVYYACFSKDGSKIASCGASKALRVFKSTSGE--KLLELQAHEEDVLCCAFSPDDRHIATCASDRKVKLWNVERGVLIREFEVEHEEQIN-----------------------HCQFTNTGRRVLLATCSNDKFTN-TRLWNPNKKTSQNTMFGHMEPVNHCCFSPNDLYLATSSSDGSLKLFEVSSAN----EWKSIDVD------------------------------------SFFPESD---EEIKAMVKCSTWSADGSQIICAARNTVFVFDVETSD-LLLKLKTSRLSTIQFCHACPNSSLLAVALSHYTVELWNFESSKKKAECSGH----LSWVHC---------------------VQFSPDGSLLLSSSDDQTIRLWETDR-------VHTSSAVALKRDTDVLSSHSDATIIAPDSSNRLQVLSGSTGAVVLESEELSSRIRCSCISRNAAFVALGSEDGTVQVIEVPSSKASVKLSGHTKTVHHCQFTDDCEILITSSEDSTIRVWKWRTGECMVLQGHMEPVRKFHLLSSSSSPHLFSWSFDGTVKVWDLTRG---QMLQDLVCHEGAVLSCDVSSDGRLFATTSANRTAKVWSSA---SWKMLFLLEGHKDCVRSCRFSWDNKRLATGDDNGEIRLWSMLDGA----------------LLKICPRDTKDSMNSYHAGWVTDLHFSPDNRVLVSTAGYIKWWS----VESGEALQTFYTMGGNLKKIHVSPDFSTFITVDSIGILYILKRLEGEGT---------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KLI1-1", "uniprot_id": "APAF_DROME", "id": "Q7KLI1-1", "name": "Apoptosome protein Dark", "aln": "MDFETGEHQYQYKDILSVFEDAFVDNFDCKDVQDMPKSILSKEEIDHIIMSKDAVSGTLRLFWTLLSKQEEMVQKFVEEVLRINYKFLMSPIKTEQRQPSMMTRMYIEQRDRLYNDNQVFAKYN-------VSRLQPYLKLRQALLELR-PAKNVLIDGVLGSGKTWVALDVCLS-YKVQCKMDFKIFWLNLKNCNSPETVLEMLQKLLYQIDPNWTSRSDHSSNIKLRIHSIQAELRRLLKSKPYENCLLVLLNVQNAKAWNAFNLSCKILLTTRFKQVTDFLSAATTTHISLDHHSMTLTPDEVKSLLLKYLDCRPQDLPREVLTTN------PRRLSIIAESIRDGLATWDNWKHVNCDKLTTIIESSLNVLEPAEYRKMFDRLSVFPPSAHIPTILLSLIWFDVIKSDVMVVVNKLHKYSLVEKQPKESTISIPSIYLELKVKLENEYALHRSIVDHYNIPKTFDSDDLIPPYLDQYFYSHIGHHLKNIEHP----ERMTLFRMVFLDFRFLEQKIRHDSTAWNASGSILNTLQQLKFYKPYICDNDPKYERLVNAILDFLPKIEENLICSKYTDLLRIALMAED-EAIFEEAHKQVQRFDDR-----VWFTNHGRFHQHRQIINLGDNEGRHAVYLHNDFCLIALASGQILLTDVSLEGEDTYLLRDESDSSDILRMAVFNQQKHLITLHCNGSVKLWSLWPDCPGRRHSGGSKQQLVNSVVKRFIGSYANLKIVAFYLNEDAGLPEANIQLHVAFINGDVSILNWDEQDQEFKLSHVPVLKTMQSGIRCFVQVLKRYYVVCTSNCTLTVWDLTNGSSNTLELHVFNVENDTPLALDVFDERSKTATVLLIFKYSVWRLNFLPGLSVSLQSEAVQLPEGSFITCGKRSTDGRYLLLGTSEGLIVYDLKISDPVLRSNVSEHIECVDIYELFDPVYKYIVLCGAKGKQVVHVHTLRSVSGSNSHQNREIAWVHSADEISVMTKACLEPNVYLRSLMDMTRERTQLLAVDSKERIHLIKPAISRISEWSTITPTHAASNCKINAISAFNDEQIFVGYVDGVIIDVIHDTALPQQFIEEPIDYLKQVSPNILVASAHSAQKTVIFQLEKIDPLQPNDQWPLMMDVSTKYASLQEGQYIILFSDHGVCHLDIANPSAFVKPKDSEEYIVGFDLKNSLLFLAYENNIIDVFRLIFSCNQLRYEQICEEEIAQKAKISYLVATDDGTMLAMGFENGTLELFAVENRKVQLIYSIEEVHEHCIRQLLFSPCKLLLIS--CAEQLCFWNVTHMRNNQLEREQKRRRSRRHKQHSVTQEDAVDAAPIAADIDVDVTFVADEFHPVNRGTAELWRNKRGNAIRPELLACVKFVGNEARQFFTDAHFSHFYAIDDEGVYYHLQLLELSRLQPPPDPVTLDIANQYEDLKNLRILDSPLMQDSDSEGADVVGNLVLEKNGGVARATPILEEASS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :. : :: :* .. : : :.: .*: * :: . . : *: :* *:: .* : ::: .* * . :: * : *:* ::: * :*. . * : *: *.**: :* :. . :: : :.*:.: : : . :* :*.* :: : *.. :.. : .** .* : . ..**:* :* :. .:*: .*::***** : :** : . . * :: .:* ::: : .** :. : * :*::. :*: * : : :* . *..* . * . * :.:: . : **:: *: . :: : : . **. :* . *: : * ** :*. : : :* : *: : : . :. .: ::*. : : .. : . ::.. : :: : * * : : : :**. . * :.:::::.* : . ::.:* *.:: . *..:: * ::. . :* : .:. : : .:.: * . : ** ** ::...::* *. :: .: * : .**:*. . : .. .:*: . :.: . :: :* ..* : : * .: .:: :. :* .. . . .::: :* ::: ... * : ::*. . . : ::.* . *:** :: .: : ::: *:. *. :* . : : . :: . : . :: : .: . : . .* ::*** : :: : : :*: ...: *:: :. . . : : . :.: .: ::. : : *. * . . . ..: .:: :: : . .. : : : :* *:.. :: . : : * : * * . . :* ::. . .: .::. : : *. :: : * :::: . *: *:* ** * : :: :*.: . : . . . .. .*: * .* :. . * . . : . * : :::.....* : ::*. *: * *: ** ", "identical_positions": 140, "similar_positions": 442, "identity": "9.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000616-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55266-1", "uniprot_id": "DSRAD_RAT", "id": "P55266-1", "name": "Double-stranded RNA-specific adenosine deaminase", "aln": "--------------MSQGFRGPTGVFPHQTQP------------CLDPSYEHSKWRYLQPRGSESYLR------------------------------SFQLQQIEFLKGRLPEAPLIGAQTQ--SLPPFLPGHWPRFP---GPPAQGKQPEIWGFPR-SVTLRNQGFHIGPPLPPPHSRG----PPWRG---------------AEGLCSHFQELSISQNPE-----------------------------------QKVLNRLEELGEGKATTAYALARELRTPKKDINRILYSLERKGKLHRGVGKPPLWSLVPLSQACTQPP-------------------------------------------------RAVNSD---KEVPRGEPDLDSEDGDPASDLEGPSELLDMAEIK---EKICDYLFNVSKSSALNLAKNIGLAKARDVNAVLIDLERQGDVYR-EGATPPIWYLTDKKRERLQMKRSTHSGP------AATPAAVSEATQSTSFPTCHPPQSGG--------SSSMATSKRVEN-GQEPVTKYESRHEARPGPVRLRPHAYHNGPSRAGYVASENGPWATDDIPDNLNSIHTAPGEFRAIMEMPSFYSPTLPRCSPYKKLTECQLKNPVSGLLEYAQFTSQTCDFNLIEQSGPSHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAVKAMAILLREAKAKDSGQPEEL----SNCPMEEDPEKPAESQPPSSSATSLFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHDPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALQEEAAN-------------SADDQSGGANTDSLD----ESVAPNKIRRIGELVRYLNTNPVGGLLEYARSHGFAAEFKLIDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQDAADAALRVLIGESEKAEQLGFAEVTPVTGASLRRTMLLLSRSPDAHPKTLPLTGSTFHDQIAMLSHRCFNALTNSFQPSLLGRKILAAIIMKRDPEDMGVVVSLGTGNRCVKGDSLS-LKGETVNDCHAEIISRRGFIRFLYSELMKYNHHTAKNSIFELARGGEKLQIKKTVSFHLYISTAPCGDG---AHFDKSCSDRAVESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGAL-LTHFLQPVYLKSVTLGYLFSQG--HLTRAICCRVTRDGNAFEDGLRYPFIVNHPKVGRVSVYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPGKE--LSRVSKKNIFLQFKKLCSFRARRDLLQLS-YGEAKKAARDYDLAKNYFKKSLRDMGYGNWISKPQEEK---------------------------NFYLCPVPND--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MU3-1", "uniprot_id": "DSRAD_MOUSE", "id": "Q99MU3-1", "name": "Double-stranded RNA-specific adenosine deaminase", "aln": "--------------MSQGFRGPTGVFPHQTQS------------YLDPSHEHSKWRYPQPQGPESYPR------------------------------SFQLQQIEFLKGRLPEAPLIGIQTQ--SLPPFLPGHWPRFP---GPPAQDRQLEIWEFPR-SVTLRNQGFHIGPPLPPPHSRG----TPWRG---------------ADGLCSHFRELSISQSPE-----------------------------------QKVLNRLEELGEGKATTAHVLARELRIPKRDINRILYSLEKKGKLHRGRGKPPLWSLVPLSQAWTQPP-------------------------------------------------GVVNPDSCIQEFPRGEPGLDSEDGDPASDLEGPSEPLDMAEIK---EKICDYLFNVSNSSALNLAKNIGLTKARDVTSVLIDLERQGDVYR-QGATPPIWYLTDKKRERLQMKRSTHSAP------APTPTAVPEATRSPSFPACHPPPAGA--------SSSVAASKRVEN-GQEPAIKHESRHEARPGPMRLRPHAYHNGPSRAGYVASENGQWATDDIPDNLNSIHTAPGEFRAIMEMPSFYSPTLPRCSPYKKLTECQLKNPVSGLLEYAQFTSQTCDFNLIEQSGPSHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAVKAMAILLREAKAKDSGQPEDL----SHCPMEEDSEKPAEAQAPSSSATSLFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHDPKFQYCVAVGAQTFPPVSAPSKKVAKQMAAEEAMKALQEEAAS-------------SADDQSGGANTDSLD----ESMAPNKIRRIGELVRYLNTNPVGGLLEYARSHGFAAEFKLIDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQDAADAALRVLIGESEKAEQLGFAEVTPVTGASLRRTMLLLSRSPDAHPKTLPLSGSTFHDQIAMLSHRCFNALTNSFQPSLLGRKILAAIIMKRDPEDMGVVVSLGTGNRCVKGDSLS-LKGETVNDCHAEIISRRGFIRFLYSELMKYNHHTAKNSIFELARGGEKLQIKKTVSFHLYISTAPCGDG---ALFDKSCSDRAVESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGAL-LTHFLQPVYLKSVTLGYLFSQG--HLTRAICCRVTRDGKAFEDGLRYPFIVNHPKVGRVSVYDSKRQSGKTKETSVNWCMADGYDLEILDGTRGTVDGPGKE--LSRVSKKNIFLQFKKLCSFRARRDLLQLS-YGEAKKAARDYDLAKNYFKKSLRDMGYGNWISKPQEEK---------------------------NFYLCPVPND--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55265-1", "uniprot_id": "DSRAD_HUMAN", "id": "P55265-1", "name": "Double-stranded RNA-specific adenosine deaminase", "aln": "--------------MNP--RQGYSLSGYYTHP------------FQG--YEHRQLRYQQP-GPGSSPS------------------------------SFLLKQIEFLKGQLPEAPVIGKQTP--SLPPSLPGLRPRFPVLLASSTRGRQVDIRGVPR-GVHLRSQGLQRGFQHPSPRGRS----LPQRG---------------VDCLSSHFQELSIYQDQE-----------------------------------QRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLAKKGKLQKEAGTPPLWKIAVSTQAWNQHSGVVRPDGHSQGAPNSDPSLEPEDRNSTSVSEDLLEPFIAVSAQAWNQHSGVVRPDSHSQGSPNSDPGLEPEDSNSTSALEDPLEFLDMAEIK---EKICDYLFNVSDSSALNLAKNIGLTKARDINAVLIDMERQGDVYR-QGTTPPIWHLTDKKRERMQIKRNTNSVP------ETAPAAIPETKRNAEFLTCNIPTSNA--------SNNMVTTEKVEN-GQEPVIKLENRQEARPEPARLKPPVHYNGPSKAGYVDFENGQWATDDIPDDLNSIRAAPGEFRAIMEMPSFYSHGLPRCSPYKKLTECQLKNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEES----SHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSM-----------ASDNQPEGMISESLDNL--ESMMPNKVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLS-LKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDG---ALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGAL-LTHFLQPIYLKSVTLGYLFSQG--HLTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPRNE--LSRVSKKNIFLLFKKLCSFRYRRDLLRLS-YGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEK---------------------------NFYLCPV-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P8J0-1", "uniprot_id": "A0A8M1P8J0_DANRE", "id": "A0A8M1P8J0-1", "name": "", "aln": "MSRGRGGNYKDSQRFSLPFRKGQPQFYSSTTTGQSRGPRVPSPSSLSGSSPHPSFYSSYSSGPGVPPRDHPFPPRHSDPSLWASPQHGSDQISDSNGVSFRQNQVQFLRGQSAQAPQFKAPQPRGSQSSSRGEEVSTEPIQYQTGYRDFKSNSYSFGRRNCYGRGQDNWQGEQNFGPKKRSGWNHPHQKGQYYSNQHYKQFWNARANDLSSGIYNLSFGDRVKRVDTSDTLSCSNSSSKVSSSSSSFRDSLYLTPEIHQQVCAFLTSLRPAETIQAKVLGKKLGLPKKIVNKVLYDLLKSNQVVKQGETPPLWRLCEESRESIREKDQTQSSKDLEKEPGQSPYINQKVGGDFTTTSTP-----SPSKIPIDADSDTSDESEDSEGDDSCEKLLADQDKKTLSPTVQSVTLSTMADSKDSKEKILQYLYEAGTGNALVIAKNLGLRSAKQVNPTLYALEKQGDVNRNTEVNPPTWELSAHRQEKMDRQRKAAATANQDVNSAATLSLEDDEIANVALVNFEPMEGGGKPLVEMLDNDNVFGNTEIDIPGLEPVSKASDLSSSTHRNFQPNQFPYYQETPSNG---GEQSQWASDDIPEFLNTIR---SEVAVSLAAPPPPTQSME-SNRLQKLKEARSKNPVSGLMEFAQHLGYTCEFLLLEQSGPSHDPRFRMQVMLDGRRFPAAEGSNKKVAKKDAAAITLKILWKELDGGGGEEEEEPNIEGAGSTTDMADDMGGTDTPPQALSRSLPGGKNPVSVLMEHSQRSGHPIQFIKTGQEGPSHDPRFMFRVKVGERLFQEASAPSKKAARQLAAEEAVKELMGDGLLHLNKPPSSFCPMGDSESQPMFPACPSLPPLTAAELQAAHEAGVGDLINHLNNNAVSGLLEYARARGFAAEIRLVGQSGPSHEPKFTYQAKLGGRWFPAVCASNKKQGKQEAADAALRVLIGEAEKAARTG--ELMP----------------------ELPVSGSTIHDQIAMLSHQRFNALTARIQHSLLGRKILATIVMRNGTDSLGKVVSLGTGNRCVKGEELS-LRGDTVNDCHAEIISRRGFIRFLYSELMKHWESPGDETIFELAGDG-KLKIKSDITFHLYISTAPCGDG---ALFDKSCS-EAAELNGSGHMPLFENIKQGKLRTKVENGEGTIPVESSDIVPTWDGIQHGERLRTMSCSDKILRWNVLGLQGAL-LTHFIHPIYLHSITLGYLYSHG--HLTRAVCCRLSRDGDTFKSSLPANFTLNHPEVGRVSVYDSTRHTSKTKESSVNWSQPDQYSVEVLDGTKGKLDSPKME--VSRVSKSNLFRLFHALCQRAGRADLLALQSYAHAKMAATSFQEAKRLFFLALSQHGYGAWIGKPLEEKSFEGEAKSFEPMGGSGDVQASGCVVDPNSFLSSENNNFLSAAQGF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53065-1", "uniprot_id": "TAD1_YEAST", "id": "P53065-1", "name": "tRNA-specific adenosine deaminase 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVSCQGTRPCIVNLLTMPSEDKLGEEISTRVIN----------------------------EYSKLKSACRPIIRPSGIREWTILAG------------VAAINRDGGANKIEILSIATGVKALPDSELQRSEGKILHDCHAEILALRGANTVLLNRIQNYNPSSGDKFIQHNDEIPARFNLKENWELALYISRLPCGDASMSFLNDNCKNDDFIKIEDSDEFQYVDRSVKTILRGRLN-------FNRRNVVRTKPGRYDSNITLSKSCSDKLLMKQRSSVLNCLNYELFEKPVFLKYIVIPNLEDETKHHLEQSFHTRLPN----LDNEIKFLNCLKPFYDDKLDEEDVPGLMCSVKLFMDDFSTEEAILNGVRNGFYTKSSKPLRKHCQSQVSRFAQWELFKKIRPEYEGISYLEFK--SRQKKRSQLIIAIKNILSP-------DGWIPTRTDDVK--------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. ..: : . . :** .: . . *: : * . : :. *: .: : : . . ::*:.** :.: ...*. .*. ::******:: ** .* ..: :: .... * . ::::*. : **** ****. *:. . : * . .:. : ** ::: .: ::* * * .: : *****:* : .: ..* * :*::*: :.: * .. ** ::. *:.. :.. : :: .::. * ..* ::. : : :* . . * : *:**: : *: : . * :. .. * : *. : . ** . :: ", "identical_positions": 64, "similar_positions": 139, "identity": "4.48%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000627-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91ZS8-1", "uniprot_id": "RED1_MOUSE", "id": "Q91ZS8-1", "name": "Double-stranded RNA-specific editase 1", "aln": "------------------MDIEDEENMSSSSTDIKENRNLDNMPPKDSSTPGPGEGIPLSNGGGGSTSRKRPLEEGS--NGHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYMLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKSEPPFYVGSNGDDSFSSSGDVSLSASPVPASLTQPPLPIPPPFPPP---SGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALATVFNLHLDQTPSRQ-----PVLSEGLQLHLPQVLADAVSRLVLGKFSDLTDNFSSPHARRKVLSGVVMTTG-TDVKDAKVISVSTGTKCING-EYMSDRGLALNDCHAEIISRRSLLRFLYAQLELYLNN-KEDQKKSIFQKSERGGFRLKDTVQFHLYISTSPCGDARIFSPHEPVLEG----------------MTP--------------DSHQLTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSL-LSIFVEPIYFSSIILGSLYHG--DHLSRAMYQRISN-IEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDATIEVINATTGKDELGRPSRLCKHALYCRWMRVHGKVPPHLLRTKITKPTTYHESKLAAREYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSFTP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51400-1", "uniprot_id": "RED1_RAT", "id": "P51400-1", "name": "Double-stranded RNA-specific editase 1", "aln": "------------------MDIEDEENMSSSSIDVKENRNLDNMPPKDSSTPGPGEGIPLSNGGGGSTSRKRPLEEGS--NGHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYMLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKSEPPFYVGSNGDDSFSSSGDVSLSASPVPASLTQPPLPIPPPFPPP---SGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALATVFNLHLDQTPSRQ-----PVLSEGLQLHLPQVLADAVSRLVLGKFSDLTDNFSSPHARRKVLSGVVMTTG-TDVKDAKVISVSTGTKCING-EYMSDRGLALNDCHAEIISRRSLLRFLYAQLELYLNN-KEDQKKSIFQKSERGGFRLKDTVQFHLYISTSPCGDARIFSPHEPVLEG----------------MAP--------------DSHQLTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGAL-LSIFVEPIYFSSIILGSLYHG--DHLSRAMYQRISN-IEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDTAIEVINATTGKDELGRPSRLCKHALYCRWMRVHGKVPPHLLRTKITKPTTYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSFTP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P78563-1", "uniprot_id": "RED1_HUMAN", "id": "P78563-1", "name": "Double-stranded RNA-specific editase 1", "aln": "------------------MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGS--NGHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPP---SGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLHLDQTPSRQ-----PIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG-TDVKDAKVISVSTGTKCING-EYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNN-KDDQKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSL-LSIFVEPIYFSSIILGSLYHG--DHLSRAMYQRISN-IEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLTP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P669-1", "uniprot_id": "A0A8M1P669_DANRE", "id": "A0A8M1P669-1", "name": "", "aln": "MNEVGASGRPRGQQKFCSLDVDEDKHLSTCSMDVKENRNLDNLSSKE----VLGEGPHLANGSARGLSRKRPLEEGNKGHGHSKFRPKKRRKPQGPILPKNALMQLNEIKPGLQYKLLSQTGPVHAPVFVMTVEVNGQLFEGSGPTKKKAKLNAAEKALRSFVQFPNASEAHLAMGRTLTVNADFTSDQADFPDMLFNGFETPVPPDDPFYLSLGSNGSLCSLKEYRLPVTLKYKNRPHPPLPLAPALTAPPTGSGKNAVMILNELRPGLKYEFVAESGESHAKNFIMSVTVDTQKFQGSGRNKKLAKARAAQAALSGLFNMQLDQTPSRQ-----PIPREGLQLHLPQVLADAVSRLVVDKFSELTDNFSSPHARRKVLAGVVMTTG-KDVMDAQVICVTTGTKCING-EYMSDRGLALNDCHAEIIARRSLIRYLYNQLEYFLSDSTEEHEKSIFRWCSEHGYRLKDDIQFHLYISTSPCGDARIFSPHEAGAED----------------------------------------QGDRHPNRKARGQLRTKIESGEGTIPVRTSNTIQTWDGVLQGERLLTMSCSDKIARWNVIGVQGSL-LSYFTEPIYFSSLILGSLYHA--DHLSRAMYQRIAD-MDDIPPPFRINRPLLSGISNTEARQPGKAPNFSVNWTVGDQGLEIINATTGKDDLGRQSQLCKHALYSRWVCLHAKLS-ETLRIRGSRPGSYHEAKQGAVEYHEAKQTLFKAFYKAGLGAWVEKPIEQDQFSLTP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NII1-1", "uniprot_id": "ADAR_DROME", "id": "Q9NII1-1", "name": "Double-stranded RNA-specific editase Adar", "aln": "--------------------MLNSANNNSPQHPVSAPSDIN------------------MNGYNRKLPQKRGYEMPK--YSDPKKKMCKERIPQ----PKNTVAMLNELRHGLIYKLESQTGPVHAPLFTISVEVDGQKYLGQGRSKKVARIEAAATALRSFIQFKDG--AVLSP-LKPAGNLDFTSD-----EHLENGIENLSSSKMFEIIQTMLTEKLSNPTSLEQPTFCMSQNVSKSAITVDGQKKVP----DKGPVMLLYELFNDVNFECINIDGAQNNCRFKMTVTINEKKFDGTGPSKKTAKNAAAKAALASLCNISYSPMVVPQKNVPLPIDDKSSSMELPQIHADTIGRLVLEKFMEVIKGQE-AYSRRKVLAGIVMTEN-MNFCEAKVISVSTGTKCVSG-EHMSVNGAVLNDSHAEIVSRRCLLKYLYAQLDLQCNQATAYQSIFVRNTDGQYPYKLKSGVHFHLYINTAPCGDARIFSPHENDTG------------------------------------------VDKHPNRKARGQLRTKIESGEGTIPVKSSDGIQTWDGVLQGQRLLTMSCSDKIARWNIVGIQGSL-LSSIIEPVYLHSIVLGSLLHP--EHMYRAVCGRIEKSIQGLPPPYHLNKPRLALVTSAEPRNQAKAPNFGINWTIGDTELEVVNSLTGRTIGGQVSRITKQAFFVKYGFLMANLPGILVRKVTT---DYGQTKANVKDYQIAKLELFSAFKREDLGSWLKKPIEQDEFGLAE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53065-1", "uniprot_id": "TAD1_YEAST", "id": "P53065-1", "name": "tRNA-specific adenosine deaminase 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVSCQGTRPCIVNLLTMPSEDK---------------LGEEISTRVINEYSKLKSACRPIIR---PSGIREWTILAGVAAINRDGGANKIEILSIATGVKALPDSELQRSEGKILHDCHAEILALRGANTVLLNRIQNYNPS--SGDKFIQHNDEIPARFNLKENWELALYISRLPCGDASMSFLNDNCKND---------------------------------------DFIKIEDSDEFQYVDRSVKTILRGRLNFNRRNVVRTKPGRYDSNITLSKSCSDKLLMKQRSSVLNCLNYELFEKPVFLKYIVIPNLEDETKHHLEQSFHTRLPN-LDNEIKFLNCLKPFYDDKLDEE-----DVPGLMCSVKLFMDDFSTEEAILNGVRNGFYTKSSKPLRKHCQSQVSRFAQWELFKKIRPEYEGISYLEFKSRQKKRSQLIIAIKNILS-PDGWIPTRTDDVK-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .::..: : .: . .:. : .:* : . .:*:*:. . . :::.::**.*.: . * .* *:*.****:: * * ::: . .. . :.**. .: ***. ***** : :: . . . : : *: .* : .. ::* * :.: *: *****: : .: ..* . : :*::: ::: .* . .*: ::. *: . ::. :* . * ..*.: . .: :. :: . * :: * : .: . : : : :: : ..*: . :: : ", "identical_positions": 47, "similar_positions": 134, "identity": "6.06%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000629-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NHW5-1", "uniprot_id": "RLA0L_HUMAN", "id": "Q8NHW5-1", "name": "Putative ribosomal protein uL10-like", "aln": "MPREDRATWKSNYFLKIIQLLDDYPKCFIVGADNVGSKQMQQIRMSLRGKVVVLMGKN-TMMRKAIRGHLENNPALEKLLPHIWGNVGFVFTKEDLTEIRDMLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNML---NISPFSFGLVIQQVFDNGSIYNPEVLDKTEETLHSRFLEGVRNVASVCLQTGYPTVASVPHSIINGYKRVLALSVETDYTFPLAENVKAFLADPSAFVAAAPVAADTTAAPAAAAAPAKVEAKEESEESDEDMGFGLFD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05388-1", "uniprot_id": "RLA0_HUMAN", "id": "P05388-1", "name": "Large ribosomal subunit protein uL10", "aln": "MPREDRATWKSNYFLKIIQLLDDYPKCFIVGADNVGSKQMQQIRMSLRGKAVVLMGKN-TMMRKAIRGHLENNPALEKLLPHIRGNVGFVFTKEDLTEIRDMLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNML---NISPFSFGLVIQQVFDNGSIYNPEVLDITEETLHSRFLEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFVAAAPVAAATTAAPAAAAAPAKVEAKEESEESDEDMGFGLFD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19945-1", "uniprot_id": "RLA0_RAT", "id": "P19945-1", "name": "Large ribosomal subunit protein uL10", "aln": "MPREDRATWKSNYFLKIIQLLDDYPKCFIVGADNVGSKQMQQIRMSLRGKAVVLMGKN-TMMRKAIRGHLENNPALEKLLPHIRGNVGFVFTKEDLTEIRDMLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNML---NISPFSFGLIIQQVFDNGSIYSPEVLDITEQALHTRFLEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFAAAAPVAAATTAAPAAAAAPAKVEAKEESEESDEDMGFGLFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14869-1", "uniprot_id": "RLA0_MOUSE", "id": "P14869-1", "name": "Large ribosomal subunit protein uL10", "aln": "MPREDRATWKSNYFLKIIQLLDDYPKCFIVGADNVGSKQMQQIRMSLRGKAVVLMGKN-TMMRKAIRGHLENNPALEKLLPHIRGNVGFVFTKEDLTEIRDMLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNML---NISPFSFGLIIQQVFDNGSIYNPEVLDITEQALHSRFLEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETEYTFPLTEKVKAFLADPSAFAAAAPAAAATTAAPAAAAAPAKAEAKEESEESDEDMGFGLFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZJT4-1", "uniprot_id": "D3ZJT4_RAT", "id": "D3ZJT4-1", "name": "60S acidic ribosomal protein P0", "aln": "MPREDRVTCKSNYFLKIIQLLDDYPKCFIMGADNVSSKQMQQIRMSLQGKAVVLMIKNNAMMRKAIREHLEKNRALEKLPPHTRGNVGFMFTKEDLTEIRDMLLTNKVPAATQAGALAPCEVTAHAQNTGLGPEKTSFFQVLGINTKISRGIIEILSDVQLIKTGNKVGAGEATLL------NISPSVSGLIIRQVFDNGSIYNPEVLDITEQILRSHFLEGVRNVAAVCLQIGEPTVTSVPHSIINGSKRVLALSVETDYTFPLAEKVKAFLADPSAFAAAAPVAAATTAAPAAAAAPAKAKAKEESEESDEDVRFGLFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9PV90-1", "uniprot_id": "RLA0_DANRE", "id": "Q9PV90-1", "name": "Large ribosomal subunit protein uL10", "aln": "MPREDRATWKSNYFLKIIQLLDDFPKCFIVGADNVGSKQMQTIRLSLRGKAVVLMGKN-TMMRKAIRGHLENNPALERLLPHIRGNVGFVFTKEDLTEVRDLLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKPGDKVGASEATLLNMLNMLNISPFSYGLIIQQVYDNGSVYSPEVLDITEDALHKRFLKGVRNIASVCLQIGYPTLASIPHTIINGYKRVLAVTVETDYTFPLAEKVKAYLADPTAFAVAAPVAAATEQKSAAPAAKEEAP-KEDSEESDEDMGFGLFD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P19889-1", "uniprot_id": "RLA0_DROME", "id": "P19889-1", "name": "Large ribosomal subunit protein uL10", "aln": "MVRENKAAWKAQYFIKVVELFDEFPKCFIVGADNVGSKQMQNIRTSLRGLAVVLMGKN-TMMRKAIRGHLENNPQLEKLLPHIKGNVGFVFTKGDLAEVRDKLLESKVRAPARPGAIAPLHVIIPAQNTGLGPEKTSFFQALSIPTKISKGTIEIINDVPILKPGDKVGASEATLLNML---NISPFSYGLIVNQVYDSGSIFSPEILDIKPEDLRAKFQQGVANLAAVCLSVGYPTIASAPHSIANGFKNLLAIAATTEVEFKEATTIKEYIKDPSKFAAAASASAAPAAGGATEKKEEAKKPESESEEEDDDMGFGLFD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05317-1", "uniprot_id": "RLA0_YEAST", "id": "P05317-1", "name": "Large ribosomal subunit protein uL10", "aln": "--MGGIREKKAEYFAKLREYLEEYKSLFVVGVDNVSSQQMHEVRKELRGRAVVLMGKN-TMVRRAIRGFLSDLPDFEKLLPFVKGNVGFVFTNEPLTEIKNVIVSNRVAAPARAGAVAPEDIWVRAVNTGMEPGKTSFFQALGVPTKIARGTIEIVSDVKVVDAGNKVGQSEASLLNLL---NISPFTFGLTVVQVYDNGQVFPSSILDITDEELVSHFVSAVSTIASISLAIGYPTLPSVGHTLINNYKDLLAVAIAASYHYPEIEDLVDRIENPEKYAAAAPAATSAASGDAAPAEEAAAE---EEEESDDDMGFGLFD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *::** *: : :::: . *::*.***.*:**: :* .*:* .**** ** :*:*:*** .*.. :*:* *. *****:**: *:*::: :: .:* *.::.**:** .: * ***: * ******.*.: ***::* ***:.** ::..*:*** .**:** **** ** : **:*.*.:: ..:** . : * :* ..* .:*::.* * **:.* *:: *. * :**:: :. : : : :* :..**..:: . *: :.**.*:*: *****", "identical_positions": 113, "similar_positions": 108, "identity": "35.2%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000629-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P25427-1", "uniprot_id": "NGF_RAT", "id": "P25427-1", "name": "Beta-nerve growth factor", "aln": "MSMLFYTLITAFLIGVQAEPYTDSNVPEGDSVPEAHWTKLQHSLDTALRRARSAPAEPIAARVTGQTRNITVDPKLFKKRRLRSPRVLFSTQPPPTSSDTLDLDFQAHGTISFNRTHRSKRSSTHPVFHMGEFSVCDSVSVWVGDKTTATDIKGKEVTVLGEVNINNSVFKQYFFETKCRAPNPVESGCRGIDSKHWNSYCTTTHTFVKALTTDDKQAAWRFIRIDTACVCVLSRKAARRG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P01139-1", "uniprot_id": "NGF_MOUSE", "id": "P01139-1", "name": "Beta-nerve growth factor", "aln": "MSMLFYTLITAFLIGVQAEPYTDSNVPEGDSVPEAHWTKLQHSLDTALRRARSAPTAPIAARVTGQTRNITVDPRLFKKRRLHSPRVLFSTQPPPTSSDTLDLDFQAHGTIPFNRTHRSKRSSTHPVFHMGEFSVCDSVSVWVGDKTTATDIKGKEVTVLAEVNINNSVFRQYFFETKCRASNPVESGCRGIDSKHWNSYCTTTHTFVKALTTDEKQAAWRFIRIDTACVCVLSRKATRRG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P01138-1", "uniprot_id": "NGF_HUMAN", "id": "P01138-1", "name": "Beta-nerve growth factor", "aln": "MSMLFYTLITAFLIGIQAEPHSESNVPAGHTIPQAHWTKLQHSLDTALRRARSAPAAAIAARVAGQTRNITVDPRLFKKRRLRSPRVLFSTQPPREAADTQDLDFEVGGAAPFNRTHRSKRSSSHPIFHRGEFSVCDSVSVWVGDKTTATDIKGKEVMVLGEVNINNSVFKQYFFETKCRDPNPVDSGCRGIDSKHWNSYCTTTHTFVKALTMDGKQAAWRFIRIDTACVCVLSRKAVRRA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6YBR5-1", "uniprot_id": "NGF_DANRE", "id": "Q6YBR5-1", "name": "Nerve growth factor", "aln": "--MRWSMLVLLLLSCSQTFAQR-----PGDICPQ----NPHHGQDVT---ANTVP---------------TVDPKLFNKRRYRSPRVLFSEHPPDSEPS----------------RSRTKR-KAGPPQHRGVYSVCESISHWEGNKTKATDITGNEVTVLPDVIINNSKKKQYFFETTCSSGRTGGSGCLGIDARHWNSYCTNSHTFVRALTSFKNLVAWRLIRINVACVCVLSRKSWRA-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : *: :* *: . *. *: : :*. *.: *.:.* ****:**:*** :******* :** .. *:** .: * * * :***:*:* * *:**.****.*:** ** :* **** :******.* .. *** ***::*******.:****:*** : .***:***:.*********: * ", "identical_positions": 100, "similar_positions": 47, "identity": "41.49%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000629-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62961-1", "uniprot_id": "YBOX1_RAT", "id": "P62961-1", "name": "Y-box-binding protein 1", "aln": "-----------------MSSEAETQQPPAAP--AAALSAADTKPGSTGSGAGSGGPGGLTSAAPAG---------------GDKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSKYAADRNHYRR--YPRRRGPPRNYQQNYQN---SESGEKNEGSES-APEG-----QAQQRRPYR-----RRRFPPYYMRRPYARRPQYSNPPV--QGEVMEGADNQGAGEQG-RPVRQNMYRG--YRPRFR-RGPPRQRQPREDGNEEDKENQGDETQGQQPPQRR-YRRNFNYRRR-RPENPKPQDGKETKAADPPAENSSAPEAEQGGAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZEV0-1", "uniprot_id": "D3ZEV0_RAT", "id": "D3ZEV0-1", "name": "", "aln": "-----------------MSSEAETQQPPAAP--AAALSAADTKPGSTGSGAGSGGPGGLTSAAPAG---------------GDKKVIATKVLGTVKWFNVRNGYGFINSNDTREDVFVHQTAIKKNKPRKYLRSV----------VEGEKGAEAANVTGPGGVPVQGSKYAADRNHYRR--YPRRRGPPRNYQQNYQN---SESGEKNEGSES-APEG-----QAQQRRPYR-----RRRFPPYYMRRPYARRPQYSNPPV--QGEVMEGADNQGAGEQG-RPVRQNMYRG--YRPRFR-RGPPRQRQPREDGNEEDKENQGDETQGQQPPQRR-YRRNFNYRRR-RPENPKPQDGKETKAADPPAENSSAPEAEQGGAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62960-1", "uniprot_id": "YBOX1_MOUSE", "id": "P62960-1", "name": "Y-box-binding protein 1", "aln": "-----------------MSSEAETQQPPAAP--AAALSAADTKPGSTGSGAGSGGPGGLTSAAPAG---------------GDKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSKYAADRNHYRR--YPRRRGPPRNYQQNYQN---SESGEKNEGSES-APEG-----QAQQRRPYR-----RRRFPPYYMRRPYARRPQYSNPPV--QGEVMEGADNQGAGEQG-RPVRQNMYRG--YRPRFR-RGPPRQRQPREDGNEEDKENQGDETQGQQPPQRR-YRRNFNYRRR-RPENPKPQDGKETKAADPPAENSSAPEAEQGGAE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GL75-1", "uniprot_id": "A0A8I6GL75_RAT", "id": "A0A8I6GL75-1", "name": "", "aln": "-----------------MSSEAETQQPPAAP--AAALSAADTKPGSTGSGAGSGGPGGLTSAAPAG---------------GDKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSKYAADRNHYRR--YPRRRGPPRNYQQNYQN---SESGEKNEGSES-APEG-----QAQQRRPYR-----RRRFPPYYMRRPYARRPQYSNPP--------------GAGEQG-RPVRQNMYRG--YRPRFR-RGPPRQRQPREDGNEEDKENQGDETQGQQPPQRR-YRCNFNYRRR-RPENPKPQDGKETKAADPPAENSSAPEAEQGGAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P67809-1", "uniprot_id": "YBOX1_HUMAN", "id": "P67809-1", "name": "Y-box-binding protein 1", "aln": "-----------------MSSEAETQQPPAAPPAAPALSAADTKPGTTGSGAGSGGPGGLTSAAPAG---------------GDKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSKYAADRNHYRR--YPRRRGPPRNYQQNYQN---SESGEKNEGSES-APEG-----QAQQRRPYR-----RRRFPPYYMRRPYGRRPQYSNPPV--QGEVMEGADNQGAGEQG-RPVRQNMYRG--YRPRFR-RGPPRQRQPREDGNEEDKENQGDETQGQQPPQRR-YRRNFNYRRR-RPENPKPQDGKETKAADPPAENSSAPEAEQGGAE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B5DE31-1", "uniprot_id": "YBOX1_DANRE", "id": "B5DE31-1", "name": "Y-box-binding protein 1", "aln": "-----------------MSSEAETQQPPQPA--------ADAESPSS------------PAAAATA---------------GDKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSKYAADRNRYRR--YPRRRAPPRDYQENYQSDPEAEPREKREGAES-APEGEM---QQQQRRPTYP---GRRRYPPYFVRRRYGRRPPYTNSQRGEMTEGGEGEENQGGPDQGNKPMRQNYYRG--FRP--S-RGPSRPR-PVRDG-EEDKENQSESGQNQEPRQRR-YRRNFNYRRR-RPQTTKPQDGKDSKAADASADKSAAPEAEQGGAD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q62764-1", "uniprot_id": "YBOX3_RAT", "id": "Q62764-1", "name": "Y-box-binding protein 3", "aln": "MSEAGEATTGG-TTLPQAAADAPAAAPPDPAPKSPAASGAPQ--APAPAALLAGSPGGDAAPGPAPASSAP-----AGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEE----EGSGSSEGFEPPAADGQFSGARNQLRRPQYRPPYRQRRFPPYHVGQTFDRRSRVFPHPN--RMQAGEIGEMKDGVPEG-AQLQ--VHRNPTYRPRFR-RGPARPRPAPAIGEAEDKENQQAANGPNQPSARRGFRRPYNYRRRPRPLNAVSQDGKETKAGEAPTEN-PAPATEQSSAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16989-1", "uniprot_id": "YBOX3_HUMAN", "id": "P16989-1", "name": "Y-box-binding protein 3", "aln": "MSEAGEATTTTTTTLPQAPTEAAAAAPQDPAPKSPVGSGAPQAAAPAPAAHVAGNPGGDAAPAATGTAAAASLATAAGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEE----EGSGSSEGFDPPATDRQFSGARNQLRRPQYRPQYRQRRFPPYHVGQTFDRRSRVLPHPN--RIQAGEIGEMKDGVPEG-AQLQGPVHRNPTYRPRYRSRGPPRPRPAPAVGEAEDKENQQATSGPNQPSVRRGYRRPYNYRRRPRPPNAPSQDGKEAKAGEAPTEN-PAPPTQQSSAE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::* : * .. * .: .:...: .:***:********************* ***:*************:******** ***************.****:**:*****.:*** * ***.***:* : :. * . ** :. *.: : * *** :**:***.: : : **. .. :* :: :*. :** ***.* * . * ****** ::* ** :* :***** ** .. .****::**.:..::: .** ::*..*:", "identical_positions": 140, "similar_positions": 74, "identity": "36.84%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000705-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E1JHB7-1", "uniprot_id": "E1JHB7_DROME", "id": "E1JHB7-1", "name": "", "aln": "MAMLPRLILLPLLLILRISWSDAVPLQQFSPDPDDSIENCGGENGAPLMTPCKSAIILDAQTSTTLKCEDDEPMSWWTSQSQYVHVKSFDNTEDPARPFGTSLHLIEVTADYVAAYYCVKTSKFSQIAKEEQSDEAMIELVNQGYASSIYVYVNDPDTKLVDS----HNVVTARQYTDVVIPCKPAMPDTEVLLETSNGEMHSSKSVG-RYDPQRGFTIEIRSIVDGGDYYCRPNPPFPHNEEEMTSIEVRFIATGLDIPRTQTTNMVYTYAPGVTDGDDEVLTVTNQSTGNLALIRGGDGTLSRERARRSPARLAPMNASPSPRPGQDGKPLPKPVIRSSVEHHVFTDTNFTLDCEQSAYVESVYGMEWFTPSRDENRIFASQSRTDPKTRNSTHQTGRSTLTVLNAQPSDTGLYKCVTTDNSNQNVQRATYRIKVLKQNESYLNVGEPSGHYNVQEYANRTIQMTANFEGFPTPSFSWFKPDGTEVRQSENNFKILSTELSTMLQVLNAQLQDSGTYVLRGSNSFGVVQR--------EYNVSVMDAPALKMSDAYVQVGSVARLECTVRSYPPAIVTFFFRPCSLEPQWPTCSVLNQNFSLPSEQEKYQFQTRPRPGKLSVERIYEVSFLPTEPGILTCIAQNIIDGKERRTLTKAHVLLGNISENMTIYGFDKDHKIAKEDNVNFTCEALAYHFDGNLKWFINGEDLKESDSVHIETSHTKYSYKSTVHITTISDRDRGTYECRAYHNDKDAVYSSREIDLYVHDPSAPQWTNGGQEGHSKIKRKLSQTLELECASTAVPVAIVRWFKDDKEVTESKLRHIIEKESKLLITHLYPGDEGVYKCVVENRLDRIERSFTVVISDLPGISMAWVWFGVILFLILIGLCVFLAVRYQKEHKRHLALKAAGLANFEEGAVGHINPDLTLDEQAELLPYN-REFEFPRENLKLGKQLGAGAFGVVLKGEAKGIRREEPTTTVAVKMVKATADNEVVRALVSELKIMVHLGQHLNVVNLLGAVTKNIAKRELMVIVEYCRFGNIQNFLLRNRKCFINQINPDTDHIDPSIMTQRMSDNYELHRDTNGGGLKYANVGFPIHSYINEPHNNNTQPPTHRRNSDNDPRSGTRAGRTGSGTATYSYDRQMDTCATVMTTVPEDDQIMSNNSVQPAWRSNYKTDSTEAMTVTTVDLISWAFQVARGMDYLSSKKVLHGDLAARNILLCEDNVVKICDFGLARSMYRGDNYKKSENGKLPIKWLALESLSDHVFSTYSDVWSYGIVLWEMFSLAKVPYPGIDPNQELFNKLNDGYRMEKPKFANQELYEIMLECWRKNPESRPLFAELEKRFANMLGEDVASHYLDLNNPYMQSNIEYMKKQSTDYLALMGSPDELAPAAPRYVNGHIVPDIRIEELPDDYMEMSRDSDPDACTAIFSPTRLEGESSDFPDFSSETTFNFPGARQSPTLSNNLNSGSSKPLRKKNGMPTVDVADQAPEEIPMLHRSSTGSDGSPEQGRRFNQALKQQYVTPTPSPRHHVETKLNGEPSENYVNMKPPRKNIPGKTTTGGGGAAAGASTEAFSNPSYQPLSTVNEKEQRRY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8AXB3-1", "uniprot_id": "VGFR4_DANRE", "id": "Q8AXB3-1", "name": "Vascular endothelial growth factor receptor kdr-like", "aln": "--------MTPLKTSVKAFFTLHVLFSCISHGLVE-----GSRLPDPQLLPDGDTHLQHVGGTLTLICRGSTALHWRLASRNVSSVR-IESCEERLHKHCSKLVIHNLRHNDTGIYSCSHK-------------------KSSDHEVSTYVFVKDPHHPFVEAYSLPHPLFAYRNDPYFVVPCRTTYPNQNVILETQMNPMADDVKRGVQWDPKKGFTVPLKPYDS------------------------------------------YHLITCLTRVDNAEFSSVYLLKRLTMEIKN--LAIEPERPR------------------------------------VLVGDTLILNCSAETTYNGRIHFEWEFH---KERINRTHHFSTTPVQLAQIMVMSKALIVPNVTMEDKGTYTCTGS----IEFKKLQMSTKVIVYEHPFLNVTHNKRKFTSTVEG-RRVQFEPRVNAVPAPDRVLWYKDGVAISENSTCYETAGYNLT----IKQVRQKDAGIFTIALSNQERGLYRNISYKLEVRVKPKIFEEDVAPAGPQTFRYDQRHKLTCTAFGIPMPNITWFWQPCDPSANLTECKLYTDPLPIENVDDHFPQNP-IKDVNSKVGLLKSKNRTISTLVVKTANVSGVYSCTARNELGNRTMRIPFYVDDHPQPFEIEPSTAVAGDDITLTCRGTRYLYDR-LTWYDPLGHKVPKDETTLRIEP--YTISLSIKLPNVSRNHTLGYECQALKINTNKVVN-VTSALTIDERQGPWLMQN----LTNQDVNSSSTLTLACLAYGVPAPFITWYKDKTPVTEGPG-ITLKDDGTLIIERVKKDDEGIYECRASNDGGEAKTSAVITVVGEDGKPNIEVIILVSTGAAATFLWIMLILFIRKLRKPSSADLKTGYLSIIMDPE-----QMPLDEQCDRLPYDSNKWEFPQDRLRLGKTLGHGAFGKVVEASAFGIDKISTCKTVAVKMLKVGATNNEWRALMSELKILIHIGHHLNVVNLLGACTK--RGGPLMIIVEFCKYGNLSNYLRSKR------------------------GDFVVYKSQDGKAVRSS----------------------------------------SGCDLSELIKRRLESVASTGSSASSG--FIEDKSYCDSEEEEEEQEDLYKKVLTLEDLICYSFQVAKGMEFLASRKCIHRDLAARNILLSENNVVKICDFGLARDVYKDPDYVRKGDARLPLKWMAPEAIFDKIYTTQSDVWSFGVLMWEIFSLGASPYPGLHIDEEFCCRLKEGTRMKAPEYSSSEIYQTMLDCWHGEPSQRPTFTELVERLGDLLQASVQ----QEGKHYIPINTALLTKADPSNQSPTEETS-TRPVSLRDSGTAWNIKIRPESVKTFDEVILENGTNKIHEGGQSDSGIGLSSDDLKTLKRLESLARPRSFMSRAMKR----------KSKESVLLEGEMDKYPPLVPSLSLEDS--------------SLDSEMECHSPPPDYNYVVRYSTPPV----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** :: :: * :. :* . : *.. * : * .: : .. : ** *... .: * :. : *: ::. *: : . :.* : :: : .. * * :. ...: * **:*:**. :*:: * :.: *: . .*:**:.: *: :*:***. . * .. . * ::**::***: ::. . * . :* *: :: . . *:. ::. **.* *:.. .: *:*. .: :. :** ::** :: : . .: : . .:* * *. .*.* *.*. : :.:: **: :..:*** . . ::. . * :*: ...:..*:*. : **. : :... :: . :*: : :.: :*:* :.: **. : * . : .::: . . .: .. :* **. . * . :*:*::**. ..: . *.: .: :.: . :::: :. : : .* : . . : : *. ...: . . *. * : : : :: . : . . *::.:**.. * :* *.*: . .*.. :. . *: . ::::..:* .. ***:* : :.: * . * :.: ..* :. :: . : *.** * * : .**..:: *:**.. ***. ::.:..*:* :: .***:*:* ..* .. : * .:.: . * . * : * * ::* : :* :* * :* .: .. ::.****.: ***: .::***::.*:*** ** **** *::..* ** : .. .******:*. * *: ***:*****::*:*:********** ** **:***:*::**:.*:* :* .:: :::. :* .:: : .. : .*:::: *:. ::.... ::.::* : ..: : :. .:* ***.::****:**::*:*:* :* *********.*:************.:*:. :* :. :.:**:**:* *:: *::::* *****:*:::**:***. ****:. ::*: :*::* **: *:::..*:*: **:**: :*..** *:** :*:.::* .* : .: *: * :.* ... : ... *.: * . .** *.: : .:. . . * : : .*.*: :. :: * : * ::.. :.*:.: . *: * :* * ..: :*..: :*.* :: .: . * ", "identical_positions": 313, "similar_positions": 528, "identity": "19.67%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000710-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJH2-1", "uniprot_id": "GP173_RAT", "id": "Q9JJH2-1", "name": "Probable G protein-coupled receptor 173", "aln": "MAN---TTGEPEE-----------VSGALSLPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERALHKAPYYFLLDLCLADGIRSAICFPFVLASVRHGSSWTFSALSCKIVAFMAVLFCFHAAFMLFCISVTRYMAIAHHRFYAKRMTLWTCAAVICMAWTLSVAMAFPPVFDVGTYKFIREEDQCIFEHRYFKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMKPVQMVPAISQNWTFHGPGATGQAAANWIAGFGRGPMPPTLLGIRQNGHAASRRLLGMDEVKGEKQLGRMFYAITLLFLLLWSPYIVACYWRVFVKACAVPHRYLATAVWMSFAQAAVNPIVCFLLNKDLKKCLRTHAPCWGTGGAPAPREPYCVM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PI62-1", "uniprot_id": "GP173_MOUSE", "id": "Q6PI62-1", "name": "Probable G protein-coupled receptor 173", "aln": "MAN---TTGEPEE-----------VSGALSLPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERALHKAPYYFLLDLCLADGIRSAICFPFVLASVRHGSSWTFSALSCKIVAFMAVLFCFHAAFMLFCISVTRYMAIAHHRFYAKRMTLWTCAAVICMAWTLSVAMAFPPVFDVGTYKFIREEDQCIFEHRYFKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMKPVQMVPAISQNWTFHGPGATGQAAANWIAGFGRGPMPPTLLGIRQNGHAASRRLLGMDEVKGEKQLGRMFYAITLLFLLLWSPYIVACYWRVFVKACAVPHRYLATAVWMSFAQAAVNPIVCFLLNKDLKKCLRTHAPCWGTGGAPAPREPYCVM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NS66-1", "uniprot_id": "GP173_HUMAN", "id": "Q9NS66-1", "name": "Probable G protein-coupled receptor 173", "aln": "MAN---TTGEPEE-----------VSGALSPPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERALHKAPYYFLLDLCLADGIRSAVCFPFVLASVRHGSSWTFSALSCKIVAFMAVLFCFHAAFMLFCISVTRYMAIAHHRFYAKRMTLWTCAAVICMAWTLSVAMAFPPVFDVGTYKFIREEDQCIFEHRYFKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMKPVQMVPAISQNWTFHGPGATGQAAANWIAGFGRGPMPPTLLGIRQNGHAASRRLLGMDEVKGEKQLGRMFYAITLLFLLLWSPYIVACYWRVFVKACAVPHRYLATAVWMSFAQAAVNPIVCFLLNKDLKKCLRTHAPCWGTGGAPAPREPYCVM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I918-1", "uniprot_id": "GP173_DANRE", "id": "Q9I918-1", "name": "Probable G protein-coupled receptor 173", "aln": "MANGNASSDGPGNPLAAVVSTTGGVMGGAPSSAVSTYVKLVLLGLIICISLVGNLVVSLLVLRDRALHKAPYYFLLDLCLADTIRSAVCFPFVLVSIKNGSAWTYSVLSCKVVAFMAVLFCFHAAFMLFCISVTRYMAIAHHRFYSKRMTFWTCVAVVCMVWTLSVAMAFPPVFDVGTYKFIREEDQCIFEHRYFKANDTLGFMLMLAVLILATHVVYMKLLLFEYKHRKMKPVQMVPAISQNWTFHGPGATGQAAANWIAGFGRGPMPPTLLGIRQNLHNQNRRLLGMEEFKAEKQLGRMFYVITLFFLVLWSPYIVACYWRVFVKACTIPHRYLSTTVWMSFAQAGVNPIICFFLNKDLKKGLLAHLPPCCRTPPQLPREPYCVM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ::. * : * *. . .:.*:**********:*:**.** ::*****::****************** ****:******.*:::**:**:*.****:*********************************:****:***.**:**.*************************************************: ***.** *******:*************************************************** * .******:*.*.*********.***:**:******************::*****:*:********.****:**:******* * :* * . ********", "identical_positions": 300, "similar_positions": 50, "identity": "77.52%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000710-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60895-1", "uniprot_id": "GPR85_RAT", "id": "P60895-1", "name": "Probable G protein-coupled receptor 85", "aln": "MANYSHAADN-ILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPREPYCVI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60894-1", "uniprot_id": "GPR85_MOUSE", "id": "P60894-1", "name": "Probable G protein-coupled receptor 85", "aln": "MANYSHAADN-ILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPREPYCVI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P60893-1", "uniprot_id": "GPR85_HUMAN", "id": "P60893-1", "name": "Probable G protein-coupled receptor 85", "aln": "MANYSHAADN-ILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPREPYCVI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I919-1", "uniprot_id": "GPR85_DANRE", "id": "Q9I919-1", "name": "Probable G protein-coupled receptor 85", "aln": "MANYSHAGDHNILQNVSPLATFLKLTSLGFIIGVGVVGNLLISILLVKDKSLHRAPYYFLLDLCASDILRSAICFPFVFTSVKNGSAWTYGTLTCKVIAFLGVLSCFHTAFMLFCVSVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVPAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGIRQNSNAAGRRRLLVLDEFKTEKRISRMFYIITFFFLSLWGPYLVACYWRVFARGPVIPGGYLTAAVWMSFAQAGVNPFICIFSNRELRRCFSTTLLYCRKSRLPREPYCVI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******.*: ****:***::*************.***************:*************.**************.******:****************************:**********************************************************************************************************.****************************************:*::************ **********:**:**:*******************:***:*************:***:********************************", "identical_positions": 347, "similar_positions": 22, "identity": "93.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000710-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88426-1", "uniprot_id": "NDK6_RAT", "id": "O88426-1", "name": "Nucleoside diphosphate kinase 6, mitochondrial", "aln": "MTSILRSPQTLQLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRMRELLWKPEDCRRFYREHEGRFFYQRLVEFMTSGPIRAYILAHKDAIQLWRTLMGPTRVFRARHIAPDSIRGSLGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVHYSPEEGIHCAAETGGPKPA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88425-1", "uniprot_id": "NDK6_MOUSE", "id": "O88425-1", "name": "Nucleoside diphosphate kinase 6, mitochondrial", "aln": "MTSILRSPQALQLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRTRELQWKLEDCRRFYREHEGRFFYQRLVEFMTSGPIRAYILAHKDAIQLWRTLMGPTRVFRARYIAPDSIRGSLGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVHYSPEEGIHCAAETGGHKQPNKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75414-1", "uniprot_id": "NDK6_HUMAN", "id": "O75414-1", "name": "Nucleoside diphosphate kinase 6, mitochondrial", "aln": "MASILRSPQALQLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRMRELLWRKEDCQRFYREHEGRFFYQRLVEFMASGPIRAYILAHKDAIQLWRTLMGPTRVFRARHVAPDSIRGSFGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVCYSPEGGVHYVAGTGGLGPA---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DI51-1", "uniprot_id": "NDK6_DANRE", "id": "Q6DI51-1", "name": "Nucleoside diphosphate kinase 6, mitochondrial", "aln": "----MRCVKALQLTLAVIKPDAMAHPLILEALHQKILEN-FIIIRKKDLIWRKADSEMFYAEHSGRFFFQRLVEFMSSGPMRAYILAREDAITHWRTMMGPTKVFRARFSSPETLRGKYGLTDTRNTTHGSDSIESAKREISFFFPEFSAEEWMMREEPHFRLGHTEYNEESQIHTVKHT---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VY27-1", "uniprot_id": "Q9VY27_DROME", "id": "Q9VY27-1", "name": "Nucleoside diphosphate kinase", "aln": "----------MEITLALIKPHVLRNTYAMQQIRALISQN-FTILDQKEVCITKELSERFYAEHKGKFFYHRLTSFMNSGPSYALILQSETCIQKWRSLLGPTKVFRAVYSDPNCIRALYGISDTRNACHGSDSEASALREISILFPEFDAA-----------VGSRQAKREEA----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::***:***..: :. :: :: * .* * *: ::: .. ** **.*:**::**..** *** * ** : .* **:::***:**** . *: :*. *::****: ***** ** ***: :**:*. * . * ", "identical_positions": 59, "similar_positions": 44, "identity": "31.22%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000804-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CJE2-1", "uniprot_id": "PER3_RAT", "id": "Q8CJE2-1", "name": "Period circadian protein homolog 3", "aln": "--------------------------------MDP--CGNPAV--PGGDCPQTRGPG-------LQGSS--GQEGPLQGICVDSS----------------------------------------------------HSEHE---------DRNRMSEELIMVVQEMKKYFPAERHT--KPSTLDALNYALRCVHSVQANSEFFQSLSPRGAR-QAEATVYNLEELTSLASEHTSKN-----TDTFVAVFSFLSGRLVHISEQAAWILNSKKGFLKSLHFVDLLAPRDVRVFYAHTAP-TQLPFWNTWTQRAS-QYECAPVKPFFCRICGGG-DREQKRHYSPFRILPYLVHVHSPAQPEPE-------PCCLTLVEKIHSGYEAPRIPVDKR--VFTTTHTPGCVFLEVDERAVPLLGFLPQDLIGTSILTYLHPEDRPLMVAVHQKVLKYVGHP--PFEHSPIRFCTQNGDYVILDSSWSSFVNPWSRKVSFIIGRHKVRTSPLNEDVFATRIKKAT-SHDEDITELQEQIHRLLLQPVHASASSGYGSLGSSGSQEQHISVTSSSESSGHCVEEAQQEQMTLQQVYASVNKIKNVGQQLYIESMARSSVKPVMETCTEPQGSDEQKDFSS-SQTLKNKS-TDTGSGGDLRPEQHSSSYQQMNCIDSVIRYLTSYSFPALKRKCISCTN-TSSSS---EEAKPNPEAD--GSLRDTEQLLDIPEQE--TTTPSADAEGG--VARTLSTAALSMASGVSQCSCSSTTDHVPPLQSE--------------SVAGACEPWALRTKA-HVTAEGFKPVGLTAAVLSAHTQKEEQNYVDRFREKILTSPYGCYLQQEGRNHAKYACVVGAGATPKHSRCAGSERRKHKRKKLPTPVDSSSSSAHLCPHVRGLLP-----DVQHWSASVT-SPCATGLALPSALVVPNQTPYLLSSFPLQDMAPHGVGDSAPWGAAAECP---PLSAGPHPVSTFPSAYMGTFMTVLLHNSPLFPLWPASFSPYPFLGATGPSQMAP-LVPAMAPDLEPTPSDHGPRRVEENWETHSEEEHPFISSRSSSPLQLNLLQEEMPAPSEYADALRRG--ACPDAKQLCVTGNSGSRSPPCATGELATASVQQESP---------------------------------------------------------------------------SAAASGSSASSVHGSGSDYTSEVSENGQRSQDTHRDR--AFSGAAEESIWRMIERTPQCVLMTYQVPERGRDTVLREDLEKLHSMERQRPQFSSAQKEELAKVRSWIHSHPAPEERQLQRAMSPVKTEV------QLVTLQRPVNSVQQKTPVEQL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70361-1", "uniprot_id": "PER3_MOUSE", "id": "O70361-1", "name": "Period circadian protein homolog 3", "aln": "--------------------------------MDP--CGDPAV--PGGDCPQTRGPG-------LQGAS--GQEGPLQGTCVDSS----------------------------------------------------HSEHE---------DRNRMSEELIMVVQEMKKYFPAERHT--KPSTLDALNYALRCVHSVQANSDFFQSLGPRGAH-QADVTVYSLEDLTALASEHTSKN-----TDTFAAVFSFLSGRLVHISEQAALILNSKRGFLKSVHFVDLLAPQDVRAFYAHTAP-TQLPFWNNWTQRAS-QYECAPAKPFFCRICGGG-DRE-KRHYSPFRILPYLVHVHSSAQPEPE-------PCCLTLVEKIHSGYEAPRIPVDKR--IFTTTHTPGCVFLEVDERAVPLLGYLPQDLIGTSILTYLHPEDRPLMVAIHQKVLKYAGHP--PFEHSPVRFCTQNGEYVILDSSWSSFVNPWSRKVSFIIGRHKVRTSPLNEDVFATRIKKAA-SNDKDIAELQEQIHKLLLQPVHASASSGYGSLGSSGSQEQHVSITSSSESSGHCPEEGQHEQMTLQQVYASVNKIKNVGQQLYIESMARSSVKPVAETCVEPQGGDEQKDFSS-SQTLKNKSTTDTGSGGNLQQEQPSSSYQQMNCIDSVIRYLTSYSLPALKRKCISCTN-TSSSS---EEAKPIPEVD--SSQRDTEQLLDIRKQE--TTGPSTDIEGG--AARTLSTAALSVASGISQCSCSSTSGHAPPLQSE--------------SVAVACKPWALRTKASHLAAGGFKHVGLTAAVLSAHTQKEEQNYVDRFREKILTSPYGCYLQQESRNRAQYSCVQ-AGSTAKHSRCAGSERQKHKRKKLPAPVDTSSPGAHLCPHVTGLLP-----DEQHWGPSASPSPLGAGLAFPSALVVPSQTPYLLPSFPLQDMASQGVGVSAAWGAAAGCP---PLSAGPQAVAAFPSAYVDTLMTIFLHNAPLFPLWPPSFSPYPSLGAAGSSELAP-LVPAMAPNPEPTTSGHSQRRVEENWEAHS-EELPFISSRSSSPLQLNLLQEEMPAPSESADAVRRG--AGPDAKHHCVTGPSGSRSRHCTSGELATATAQQES-----------------------------------------------------------------------------AAASGSSASSIYFSSTDYASEVSENRQRPQDRQRDE--ALPGAAEESIWRMIERTPECVLMTYQVPERGREEVLKQDLEKLQSMEQQQPLFSPAQREELAKVRSWIHSHTAPQEGHLQSCVACEDRGS------VGDTAEVLEQHPAEDTS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56645-1", "uniprot_id": "PER3_HUMAN", "id": "P56645-1", "name": "Period circadian protein homolog 3", "aln": "---------------------------------MP--RGEAPG--PGRRGAKDEALG-------EESGERWSPEFHLQRKLADSS----------------------------------------------------HSEQQ---------DRNRVSEELIMVVQEMKKYFPSERRN--KPSTLDALNYALRCVHSVQANSEFFQILSQNGAP-QADVSMYSLEELATIASEHTSKN-----TDTFVAVFSFLSGRLVHISEQAALILNRKKDVLASSHFVDLLAPQDMRVFYAHTAR-AQLPFWNNWTQRAA-RYECAPVKPFFCRIRGGE-DRKQEKCHSPFRIIPYLIHVHHPAQPELESE-----PCCLTVVEKIHSGYEAPRIPVNKR--IFTTTHTPGCVFLEVDEKAVPLLGYLPQDLIGTSILSYLHPEDRSLMVAIHQKVLKYAGHP--PFEHSPIRFCTQNGDYIILDSSWSSFVNPWSRKISFIIGRHKVRTSPLNEDVFATKIKKMN-DNDKDITELQEQIYKLLLQPVHVSVSSGYGSLGSSGSQEQLVSIASSSEASGHRVEETKAEQMTLQQVYASVNKIKNLGQQLYIESMTKSSFKPVTGTRTEPNGGGECKTFTSFHQTLKNNS-VYTEPCEDLRNDEHSPSYQQINCIDSVIRYLKSYNIPALKRKCISCTNTTSSSS---EEDKQNHKADDVQALQAGLQIPAIPKSEMPTNGRSIDTGGG--APQILSTAMLSLGSGISQCGYSSTIVHVPPPETAR-------------DATLFCEPWTLNMQPAPLTSEEFKHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRSKAKYSYFQ-GDSTSKQTRSAGCRKGKHKRKKLPEPPDSSSSNTGSGPR-RGAHQ-----NAQPCCPSAASSPHTSSPTFPPAAMVPSQAPYLVPAFPLPAATSPGREYAAPGTAPEGLHGL-PLSEGLQPYPAFPFPYLDTFMTVFLPDPPVCPLLSPSFLPCPFLGATASSAISPSMSSAMSPTLDPPPSVTSQRREEEKWEAQS-EGHPFITSRSSSPLQLNLLQEEMPRPSESPDQMRRN--TCP-QTEYCVTGNNGSESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTGSPPMKNPSHPTASTLSMGLPPSRTPSHPTATVLSTGSPPSESPSRTGSAASGSSDSSIYLTSSVYSSKISQNGQQSQDVQKKE--TFPNVAEEPIWRMIRQTPERILMTYQVPERVKEVVLKEDLEKLESMRQQQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTCENEDS------ADGAATSCGQVLVEDSC----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PBM5-1", "uniprot_id": "A0A8M1PBM5_DANRE", "id": "A0A8M1PBM5-1", "name": "", "aln": "MPGGDGFPDGEQDNSSPGPDIHTGQTDQTSSGQDPGTSGNISA--SGEEEEAEERIGRRSSGCEESGGEQTHEDVDMNSTHTSSSGNDSIHHRHHHHHRHHHHHHHHSSSNCSPGSTTGSGSTKSSKSATGSSSSSFHSTHHTECGEQTETGREHTHREMMHTVQEMKKRLPSEKRSRSKASTVEALHYALNCVKQVQANSEYYNLLMSSGLDERRDATVCTLEELEGFTSEHTLKN-----TDSFVVVFSLASGKVVYASEQASSVLHCKRKFLESAKFVEMLYHQDVNVFYSHTAQ-PRLPSWNLGTDSAAVLFECAQVKSFFCRIRGGK-DRDGDMRYSPFRITPYLLKVQGSSG-EEE-------PCCLALAERIISGYEAPRIPMDKR--IFSTTHSPGCVFLEVDDRAVPLLGYLPQDLIGTSVLTCLHPDDRLLMLAMHRKIVKYAGQP--PFEHSPIRFRCQNGDYVTLDSSWSSFINPWSRKVAFIIGRHKVRTGPLNEDVFAARSKADQPVTCEDVKELQAMIHKLFLQPVHNNGSSGYGSLGSNGSHEHYISVASSSDSNGNLWEDSHRETMTLQQFCADVNKVKNWGQQAYLESRKK---LTALGPATAVAGAG---VHASSSHDLGIRD-HLKQSLQKARKQPHIPSYQQINCVDSIIRYLESCATSALKRKCESLSITTSSSSSTSEEDKPTSAAHENTDEAALDAARALDSQVSAGSATTAAVVGAPLTDITISTEAMSVVSVTSQCSYSSTIVHVPQPESEVTALEDAPMGSEPADSAPAPASPAPDSGSASTSQEELLVLGLTKEVLSAHTQKEEQQFVDRFRHRILQSPYSSYLQQDN-------------SSNAHSHHRGDVVRQPNKHKRPKPEDSSDSYECSQPGNYWSLPGPTAAPHSSWPSSESSQPPPSNIGFVPPMAVPMQTP---PYFNIIGADQQPVMLQPDPGVQNLQPMT-PMMVVLLP--SFPMYPPNNGMYFPMAAPGVVPYNIGGFVPPGAPMPAEAPLQGHNLESAGVGVPAEPDSIPEPWFGEDLDAAQP--TALFSSSRSSSPIQLNLLQEELTKPSEAQTSTNADSLQEPHTKTDDARSECGHQDAHSSSSEMLDQLLQEDARSGTGSNASGSGSGESGG---------------------------------------------SLGSGSGLGSNGTSTSHTGSSNSSKYFASND-SSDTSRKARKSAEAQERERSGFKKHVDDPLWSMIKQTPEPVMLTYQISSRDQAQVLQEDREKLILMQPMQPWFTSDQKKELAEVHPWIQQNTVPQEINTQGCVSCNTIEPNKKLNLQTDSPNPPDISCPQDCPPQENRPDTDT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07663-1", "uniprot_id": "PER_DROME", "id": "P07663-1", "name": "Period circadian protein", "aln": "------MEGGESTESTHNTKVSDSAYSNSCSNSQSQRSGSSKSRLSGSHSSGSSGYGGKPSTQASSSDMIIKRNKDKSRKKKKNKGAGQGAGQAQTLISASTSLEGRDEEKPRPSGTGCVEQQICRELQDQQHGEDHSEPQAIEQLQQEEEEDQSGSESEADRVEGVAKSEAAQSFPIPSPLSVTIVPPSMGGCGGVGHAAGLDSGLAKFDKTWEAGPGKLESMTGVGAAAAGTGQRGERVKEDSFCCVISMHDGIVLYTTPSITDVLGYPRDMWLGRSFIDFVHLKDRATFASQITTGIPIAESRGSVPKDAKSTFCVMLRRYRGLKSGGFGVIGRPVSYEPFRLGLTFREAPEEARPDNYMVSNGTNMLLVICATPIKSSYKVPDEILSQKSPKFAIRHTATGIISHVDSAAVSALGYLPQDLIGRSIMDFYHHEDLSVMKETYETVMKKGQTAGASFCSKPYRFLIQNGCYVLLETEWTSFVNPWSRKLEFVVGHHRVFQGPKQCNVFEAAPTCKL-----KISEEAQSRNTRIKEDIVKRLAETVSRPSDTVKQEVSRRCQALASFMETLMDEVSRADLKLELPHENELTVSERDSVMLGEISPHHDYYDSKSSTETPPSYNQLNYNENLLRFFNSKPVTAPAELDPPKTEPPEPRGTCVSGASGPMSPVHEGSGGSGSSGNFTTASNIHMSS-----VTNTSIAGTGGTGTGTGTGTGTGTGTGTGTGTGTGTGTG-------TGTGTGTGTGTGNGTNSGTGTGTASSSKGG-------------SAAIPPVTLTESLLNKHNDEMEKFMLKKHRESRGRTGEKSKKSANDTLKMLEYSGPGHGIKRGGSHSWEG------EANKPKQQLTLGTDAIKGAAGSAGGAVGTGGVGSGGAGVAGGGGS-----GTGVAGTPEGRATTTSGTGTPGGAGGGGGAGAAAAAGASSSVGSSTPGPSSYPTCTQNINLWPPFSVGITPPVHSTHTAMAQSSFSSAGLFPTFYYIPASLTPTSPTRSPRMHKHPHKGGTDMPTTSQQAAAAAAQAMPLQYMAGVMYPHPSLFYTHPAAAAATAMMYQPMPFPGMANALQIPE--------RPLGSQSAYNKSVYTTTPASMTKKVPG-------------------------------------------------------------------------------AFHSVTTPAQVQRPSSQSASVKTEPGSSAAVSDPCKKEVPDSSPIPSVMGDYNSDPPCSSSNPANNKKYTDSNGNSD-------DMDGSSFSSFYSSFIKTTDGSESPPDTEKDPKHRKLKSMSTSES--------KIMEHPEEDQTQHGDG---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *. .* * .. : . ... . : : .. *: : * .:: .. :: : :: * : . * . . :: * :. *:* *:*: .* ::: : . : :* : . . *:::: :* .* :: : :. . . : *. : : ** :.***: : .. : : : . * *.*:.* :.:: *: *:. :: .**. **. **:******* *:: * :* :* :..::* . .* .* ** *** *: *::.*:**:******: *::*:*:* .* : :** : . .: * : : : :. . ... .:* : :. :: :.*: . .:.: .. * : . . . . : : . : : . :. .. : : . : . : : ** . . . . : . : .: *.* .. .. . : . : : . :*.::. * :: .* : . . : * : . . .:.. .. . :. : . . *: . . .: * .. . . : : : ::.::. :: : :. *. .. :: : : :: :. ... :* :. . . . .: . * . .: ..* . *: . : . . :: . : : :. ", "identical_positions": 91, "similar_positions": 281, "identity": "6.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000816-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LSN4-1", "uniprot_id": "F1LSN4_RAT", "id": "F1LSN4-1", "name": "Fibroblast growth factor receptor", "aln": "MVVPACVLVFCVAV--VAGVTSEPPGPEQRVGRRAAEVPGPEPSQQEQVAFGSGDTVELSCHPPGGAPTGPTLWAKDGVGLVASHRILVGPQRLQVLNATHEDAGVYSCQQRLTRRVLCHFSVRVTDAPSSGDDED-GEDVAEDT----GAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDRELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELMEVDEAGSVYAGVLSYGVGF--FLFILVVAAVTLCRLRSPPKKGLGSPTVHKVSRFPLKRQQVSLES--NSSMNSNTPLVRIARLSSGEGPVLAN------VSELELPADPKWELSRTRLTLGKPLGEGCFGQVVMAEAIGIDKDRTAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGMDYSFDACRLP----EEQLTCKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGG-SPYPGIP-VEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRILTVTSTDEYLDLSVPFEQYSPGGQDTPSSSSSGDDSVFTHDLLPPGP------PSNGGPRT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61851-1", "uniprot_id": "FGFR3_MOUSE", "id": "Q61851-1", "name": "Fibroblast growth factor receptor 3", "aln": "MVVPACVLVFCVAV--VAGATSEPPGPEQRVVRRAAEVPGPEPSQQEQVAFGSGDTVELSCHPPGGAPTGPTVWAKDGTGLVASHRILVGPQRLQVLNASHEDAGVYSCQHRLTRRVLCHFSVRVTDAPSSGDDED-GEDVAEDT----GAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAILGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELMETDEAGSVYAGVLSYGVVF--FLFILVVAAVILCRLRSPPKKGLGSPTVHKVSRFPLKR-QVSLES--NSSMNSNTPLVRIARLSSGEGPVLAN------VSELELPADPKWELSRTRLTLGKPLGEGCFGQVVMAEAIGIDKDRTAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGMDYSFDACRLP----EEQLTCKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTPGGPSPYPGIP-VEELFKLLKEGHRMDKPASCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRILTVTSTDEYLDLSVPFEQYSPGGQDTPSSSSSGDDSVFTHDLLPPGP------PSNGGPRT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22607-1", "uniprot_id": "FGFR3_HUMAN", "id": "P22607-1", "name": "Fibroblast growth factor receptor 3", "aln": "MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDED-GEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGF--FLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKR-QVSLES--NASMSSNTPLVRIARLSSGEGPTLAN------VSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPP----EEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGG-SPYPGIP-VEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAP------PSSGGSRT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I8X3-1", "uniprot_id": "FGFR3_DANRE", "id": "Q9I8X3-1", "name": "Fibroblast growth factor receptor 3", "aln": "-MVPLCLLLYLATLVFPPVYSAHLLSPEP-----TDWVSSEVEVFLEDYVAGVGDTVVLSCTP--QDFLLPIVWQKDGDAVSSSNRTRVGQKALRIINVSYEDSGVYSCRHAHKSMLLSNYTVKVIDSLSSGDDEDYDEDEDEAGNGNAEAPYWTRSDRMEKKLLAVPAANTVKFRCPAAGNPTPSIHWLKNGKEFKGEQRMGGIKLRHQQWSLVMESAVPSDRGNYTCVVQNKYGSIKHTYQLDVLERSPHRPILQAGLPANQTVVVGSDVEFHCKVYSDAQPHIQWLKHIEVNGSQYGPNGAPYVNVLKTAGINTTDKELEILYLTNVSFEDAGQYTCLAGNSIGYNHHSAWLTVLPAVEMEREDD-----YADILIYVTSC--VLFILTMVIIILCRMWINTQKTLPAPPVQKLSKFPLKR-QVSLES--NSSMNSNTPLVRIARLSSSDGPMLPN------VSELELPSDPKWEFTRTKLTLGKPLGEGCFGQVVMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKIP----NETLTFKDLVSCAYQVARGMEYLASKKCIHRDPAARNVLVTEDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGG-SPYPGIP-VEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDHDRVLSMTSTDEYLDLSVPFEQYSPTCPDSNSTCSSGDDSVFAHDPLPEEPCLPKHHHSNGVIRT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q07407-1", "uniprot_id": "FGFR1_DROME", "id": "Q07407-1", "name": "Fibroblast growth factor receptor homolog 1", "aln": "-----------------------------------MAAAWSWRASHSTITMTSGSLVVL--------FLLLSIWQP--AVQVEGRRQMANSQ-----EMIKDHLGARSQNKTPAITNNANQSSTSSADLDDGAADD-DDNKADLPVNVSSKPYWRNPKKMS-FLQTRPSGSLLTLNCHALGNPEPNITWYRNG---TVDWTRGYGSLKRNRWTLTMEDLVPGDCGNYTCKVCNSLGCIRHDTQVIVSDRVNHKPILMTG-PLNLTLVVNSTGSMHCKYLSDLTSKKAWI-FVPCHGMTNCSNNRSIIAEDKDQ-----------LDFVNVRMEQEGWYTCVESNSLGQSNSTAYLRVVRSLHVLEAGVASGSLHSTSFVYIFVFGGLIFIFMTTLFVFYAIRKMKHEKVLKQRIETVHQWTKKVIIFKPEGGGDSSGSMDTMIMPVVRIQKQRTTVLQNGNEPAPFNEYEFPLDSNWELPRSHLVLGATLGEGAFGRVVMAEVN---------NAIVAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNGPLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYVLKIADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQ-QPYPTIMSAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKLLQTK--EDYLDVDIANLDTPPSTSDEEEDETDNLQKWCNY---------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . . *. * * :* ..* .. : : :. *. * .: .: : ..* :* .:: : *** ...:*. * : *:.. : :.* * *** *.* * :** : * .*::::*:*.**. **.* ***** * *. *.*:: : * :* *:*** :* * * * ::.* .:*** ** .: *: .: :* .:. . : * * : ** :*: * ***: .**:* .: :*:* *: : . :: : * .:**: . . : : :: : :..: ::. * .. *. ::* . :* :: :.*:.. . * * ..* *:* *.:**:.*::*.** .****.**:*****. *****:*:. **.*::.** ***:**:**:* *******.*:*.*****:****.:***:::* .** * * . *:.: * . :* ***:. *:*:****:****::***** *******::* *:**********::. ***:*.******:******:* ::.* :*****:*:*****:* * .*** * .***:. * .*:**:***.*: ::*::**:*** ..:**.* ::** *::* . ::***:. . : .* * . :.. :. : ", "identical_positions": 256, "similar_positions": 224, "identity": "30.84%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000822-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09630-1", "uniprot_id": "HXC6_HUMAN", "id": "P09630-1", "name": "Homeobox protein Hox-C6", "aln": "----------MNSYFTNPSLSCHLAGGQD------------------------------------------------------------------VLPNVALN----------STAYDPVRHFSTYGAAVAQNRI----------YSTPFYSPQENVVFSSSRGPYDYGSNSFYQEKDMLSNCRQNT----------------------------------------------------LGHNTQTSIAQDFSSEQGRTAPQDQKASIQIYPWMQRMNS--------HSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGGGATADSLGGKEEKREETEEEKQKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10629-1", "uniprot_id": "HXC6_MOUSE", "id": "P10629-1", "name": "Homeobox protein Hox-C6", "aln": "----------MNSYFTNPSLSCHLAGGQD------------------------------------------------------------------VLPNVALN----------STAYDPVRHFSTYGAAVAQNRI----------YSTPFYSPQENVVFSSSRGPYDYGSNSFYQEKDMLSNCRQNT----------------------------------------------------LGHNTQTSIAQDFSSEQGRTAPQDQKASIQIYPWMQRMNS--------HSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGGGATADSLGGKEEKREETEEEKQKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9PWM5-1", "uniprot_id": "HXC6B_DANRE", "id": "Q9PWM5-1", "name": "Homeobox protein Hox-C6b", "aln": "----------MNSYFTNPSLSCHLNSGQE------------------------------------------------------------------VLPSVAIS----------STNYDPVRHFSPYGAAVAQNRI----------YSNPFYSHQENVMFGSSR-PYDYGSNMFYQDKDVLPSCRQG-----------------------------------------------------FGQ-TQGSLTQDYASDQGKTVE--PKGVVQIYPWMQRMNS--------HR-VGYGSDRRRGRQIYSRYQTLELEKEFHYNRYLTRRRRIEIANTLCLSERQIKIWFQNRRMKWKKESNLTSILNDNGS-VGAGQDTDKEETGETAEKDEHD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18865-1", "uniprot_id": "HXC4_RAT", "id": "P18865-1", "name": "Homeobox protein Hox-C4", "aln": "-------------------------------------------------------------------------------------------------LVVMLE----------SRFPGPAR-----------------------------------------------G----------VANCRQ--------------------------------------------------------------------------------------------------------------------------QVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDH---------------DSPTPK--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P02833-1", "uniprot_id": "ANTP_DROME", "id": "P02833-1", "name": "Homeotic protein antennapedia", "aln": "MTMSTNNCESMTSYFTNSYMGADMHHGHYPGNGVTDLDAQQMHHYSQNANHQGNMPYPRFPPYDRMPYYNGQGMDQQQQHQVYSRPDSPSSQVGGVMPQAQTNGQLGVPQQQQQQQQQPSQNQQQQQAQQAPQQLQQQLPQVTQQVTHPQQQQQQPVVYASCKLQAAVGGLGMVPEGGSPPLVDQMSGHHMNAQMTLPHHMGHPQAQLGYTDVGVPDVTEVHQNHHNMGMYQQQSGVPPVGAPPQGMMHQGQGPPQMHQGHPGQHTPPSQNPNSQSSGMPSPLYPWMRSQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENK------------TKGEPGSGGEGDEITPPNSPQ-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . * : * . * *.********:*************::***:*****************: .. ", "identical_positions": 45, "similar_positions": 13, "identity": "11.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000822-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10105-2", "uniprot_id": "LAB_DROME", "id": "P10105-2", "name": "Homeotic protein labial", "aln": "MMDVSSMYGNHPHHHHPHANAYDGYSTTTASAANASSYFAPQQHQPHLQLQQQQQHQHLQQPQQHLTYNGYESSSPGNYYPQQQAQLTPPPTSSHQVVQQHQQQQQAQQQQLYPHSHLFSPSAAEYGITTSTTTGNPGTPLHPSSHSPADSYYESDSVHSYYATAAVATVAPPSNSSPITAANASATSNTQQQQQQAAIISSENGMMYTNLDCMYPTAQAQAPVHGYAGQIEEKYAAVLHASYAPGMVLEDQDPMMQQATQSQMWHHQQHLAGSYALDAMDSLGMHAHMHHGLPHGHLGNLANNPHQQQPQVQQQQQQPHQQPQHPQNQSPAAHQQHHQNSVSPNGGMNRQQRGGVISPGSSTSSSTSASNGAHPASTQSKSPNHSSSIPTYKWMQLKRNVPKPQAPKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGLGSGSGLSSCSLSSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVKEGLIPADILTQHSTSVISEKPPQQQQPQPPELQLKSQGSDLGGNELATGAPSTPTTAMTLTAPTSKQS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q98SH9-1", "uniprot_id": "HXC1A_DANRE", "id": "Q98SH9-1", "name": "Homeobox protein Hox-C1a", "aln": "------------------MNSYHGFRDTTS-----------------------------------LFIKGYHATG---------------------VMRLHQDHG------------------------------------STADFPSREDVNNEADFLQYHFTNLCATATGACSKPCEDPGRANSTRPPFPQNQ--------------------------------------------------------------------------------------------------------DFYRPVHPNRPQVPSFQSCREQGLSRKGFSPSSDTFRTFSSAHCELGPVNNTQTEVRTYDGPVRHSAVEDDNTGHGALNTLNETLHSG--KTFEWMRVRRNQSRAAKIQL---GKCSDRELKTNHGRDSDEDTSSGGS-------------------------------------------------------------------RTNFTTKQLTELEKEFHFNKYLTRARRIEIANPLQLSETQVKIWFQNRRMKQKKMLREGLAQGLMLISG----CDEDSKKSDTCSSPD-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*.*: **: * :**.::. *:: **:: .:.... :. :. .. .*: * **.: ..... ...*.:* . *:* :: . * ::*** . *. .* .: ...: : ...: . * :*. * *. *:.. .* .* * . :.. **. *::**:::** .:. :* * .* :: : * * .. ..*** *****.*************:************.***.***************** ::*** . :* . .*.. :.: ..*: ", "identical_positions": 104, "similar_positions": 109, "identity": "16.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000822-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACL0-1", "uniprot_id": "D4ACL0_RAT", "id": "D4ACL0-1", "name": "", "aln": "--------------------------------------------------------------MFNSVNLGNFCSPSRKERGADFGERGSCTSNLYLPSCTYYVPEFSTVSSFLPQAPSRQ--------------------------------------ISYPYS---AQVPPVREVSYGLEPSGKWHHRNSYSSCYAAADELMHRECLPPS--------------------------------TVTEILMKNEGSYGGHHHPSAPHAAPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDAPAEPPCSGKGE-AKGEPEAPPASGLASRAEAGAEAEAEEENTNP------------SSSGSSHSATKEPAKGAAPN--------APRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSR--------------------DRLQYFSGNPLL--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31313-1", "uniprot_id": "HXC11_MOUSE", "id": "P31313-1", "name": "Homeobox protein Hox-C11", "aln": "--------------------------------------------------------------MFNSVNLGNFCSPSRKERGADFGERGSCTSNLYLPSCTYYVPEFSTVSSFLPQAPSRQ--------------------------------------ISYPYS---AQVPPVREVSYGLEPSGKWHHRNSYSSCYAAADELMHRECLPPS--------------------------------TVTEILMKNEGSYGGHHHPSAPHAAPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDAPAEPPCSGKGE-AKGEPEAPPASGLASRAEAGAEAEAEEENTNP------------SSSGSSHSATKEPAKGAAPN--------APRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSR--------------------DRLQYFSGNPLL--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43248-1", "uniprot_id": "HXC11_HUMAN", "id": "O43248-1", "name": "Homeobox protein Hox-C11", "aln": "--------------------------------------------------------------MFNSVNLGNFCSPSRKERGADFGERGSCASNLYLPSCTYYMPEFSTVSSFLPQAPSRQ--------------------------------------ISYPYS---AQVPPVREVSYGLEPSGKWHHRNSYSSCYAAADELMHRECLPPS--------------------------------TVTEILMKNEGSYGGHHHPSAPHATPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDPPAEPPCSGKGE-AKGEPEAPPASGLASRAEAGAEAEAEEENTNP------------SSSGSAHSVAKEPAKGAAPN--------APRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSR--------------------DRLQYFSGNPLL--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ARL6-1", "uniprot_id": "A0A8M3ARL6_DANRE", "id": "A0A8M3ARL6-1", "name": "", "aln": "--------------------------------------------------------------MFNSVNIGNFCSQSRKERTSEFGERASCASNLYLPS-TYYVPEFSTVSSFLPQAQSRQ--------------------------------------ITYSYSTNFTQVPQVRDLPFELNPSGKWHHRGNYSSCY-AEEDLVHRDCLPPSA-------------------------------TMTEMLMKNENVYNHHHYHPAINHPGTGFYSSIGKTNVLPQSFDRFLDCAHSG-ADGGSEGNCLQKGSSGKPESASQVSSVLRSTADGEKELECEKNTTSG------------SFETSSGTKNDNQTKSGHST--------TPRMRKKRCPYTKFQIRELEREFFFNVYINKEKRLQLSRILNLTDRQVKIWFQNRRMKEKKLSR--------------------DRLHYFSGNPLM--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09087-1", "uniprot_id": "ABDB_DROME", "id": "P09087-1", "name": "Homeobox protein abdominal-B", "aln": "MQQHHLQQQQQQQQQQEQQHLQEQQQHLQQLHHHAHHHLPQPLHTTSHHHSAHPHLQQQQQQQQHAVVASSPSSVLQQQQQQSTPTTHSTPTHAVMYEDPPPVPLVAVQQQHLPAPQQQQQLQQQQQQQQQQLATTPVAGALSPAQTPTGPSAQQQQHLTSPHHQQLPQQQTPNSVASGASSNLQQQQQQQNAAVAPGQTQIVAPTTASVSPSSVSSQKEDINMSIQLAPLHIPAIRAGPGFETDTSAAVKRHTAHWAYNDEGFNQHYGSGYYDRK-HMFAYPYPETQFPVGQYWGPNYRPDQTTSAAAAAAYMNEAERHVSAAARQSVEGTSTSSYEPPTYSSPGGLRGYPSENYSSSGASGGLSVGAVGPCTPNPGLHEWTGQVSVRKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRMKNKKNSQRQANQQNNNNNSSSNHNHAQATQQHHSGHHLNLSLNMGHHAAKMHQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* .. .* :::: . * .:: : . . :* .:. ...** . .:* :: .: .* ..:. ... : ::: . :: . ::: . * * *. :*.. : :: : :*:*. : . * . :* : * : . . *. :: . .:. . * . . * . :: . .. **** **:*** ***:**:**.*:.*:** :*:* *:**:*************:** *: ::.**: * ", "identical_positions": 64, "similar_positions": 102, "identity": "12.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000822-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZKV8-1", "uniprot_id": "D3ZKV8_RAT", "id": "D3ZKV8-1", "name": "", "aln": "MTTSLLLHPRWPESLMYVYEDSAAES--GSGGGGGGGGAGGAGGGCSGASPGKAPSMDGLGGSCPASHCRDLLPHPVLARPPAPLGAPQGAVYTDIPAPEAARQCAPPPAPPTSSSATLGYGYPFGGSYYGCRLSH--NVNLQQKPCSYHPGDKYPEPSGALPGDDLSSRAKEFAFYPSFASSYQAMPGYLDVSVVPGISGHPEPRHDALIPVEGYQHWALSNGWDSQVYCSKEQSQSAHLWKSPFPDVVPLQPEVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKEKKVVSKSKAP-HLHST", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50207-1", "uniprot_id": "HXC13_MOUSE", "id": "P50207-1", "name": "Homeobox protein Hox-C13", "aln": "MTTSLLLHPRWPESLMYVYEDSAAES--GSGGGGGGGGAGGAGGGCSGASPGKAPSMDGLGGSCPASHCRDLLPHPVLARPPAPLGAPQGAVYTDIPAPEAARQCAPPPAPPTSSSATLGYGYPFGGSYYGCRLSH--NVNLQQKPCAYHPGDKYPEPSGALPGDDLSSRAKEFAFYPSFASSYQAMPGYLDVSVVPGISGHPEPRHDALIPVEGYQHWALSNGWDSQVYCSKEQSQSAHLWKSPFPDVVPLQPEVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKEKKVVSKSKAP-HLHST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31276-1", "uniprot_id": "HXC13_HUMAN", "id": "P31276-1", "name": "Homeobox protein Hox-C13", "aln": "MTTSLLLHPRWPESLMYVYEDSAAESGIGGGGGGGGGGTGGAGGGCSGASPGKAPSMDGLGSSCPASHCRDLLPHPVLGRPPAPLGAPQGAVYTDIPAPEAARQCAPPPAPPTSSSATLGYGYPFGGSYYGCRLSH--NVNLQQKPCAYHPGDKYPEPSGALPGDDLSSRAKEFAFYPSFASSYQAMPGYLDVSVVPGISGHPEPRHDALIPVEGYQHWALSNGWDSQVYCSKEQSQSAHLWKSPFPDVVPLQPEVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKEKKVVSKSKAP-HLHST", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6JIY5-1", "uniprot_id": "HXCDA_DANRE", "id": "Q6JIY5-1", "name": "Homeobox protein Hox-C13a", "aln": "MTTSQVLHPRWADTLMYVYEKSPNEN-----------------------NQNKSQIMEGLSGNCPATHCRELISHPALGRHSGTIATHQGSVYSDISSPETGRQC---PAPQTSSSASLSYGYPFGNPYYGCRLSHSHNVNLQQKPCSYHPAEKYAETSSALPTEELSSRAKEFAFYPSLASSYQAVPGYLDMSVVPSISVHPEPRHDALIPMEGYQHWALSNGWDGQVYCSKEQTQSSHLWKSPFPDVVPLQPEVSSYRRGRKKRVPYTKIQLKELEKEYAASKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKFVSKSKTNNHMHT-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** :*****.::******.*. *. . .*: *:**...***:***:*:.**.*.* ...:.: **:**:**.:**:.*** *** *****:*.******..******** *********:***.:**.*.*.*** ::*************:******:*****:****.** ***********:*************.********:**:********************************:*****************:*****************************.*****: *:*: ", "identical_positions": 234, "similar_positions": 58, "identity": "70.27%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000822-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZKV8-1", "uniprot_id": "D3ZKV8_RAT", "id": "D3ZKV8-1", "name": "", "aln": "MTTSLLLHPRWPESLMYVYEDSAAES--GSGGGGGGGGAGGAGGGCSGASPGKAPSMDGLGGSCPASHCRDLLPHPVLARPPAPLGAPQGAVYTDIPAPEAARQCAPPPAPPTSSSATLGYGYPFGGSYYGCRLS--HNVNLQQKPCSYHPGDKYPEPSGALPGDDLSSRAKEFAFYPSFASSYQAMPGYLDVSVVPGISGHPEPRHDALIPVEGYQHWALSNGWDSQVYCSKEQSQSAHLWKSPFPDVVPLQPEVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKEKKVVSKSK--APHLHST", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50207-1", "uniprot_id": "HXC13_MOUSE", "id": "P50207-1", "name": "Homeobox protein Hox-C13", "aln": "MTTSLLLHPRWPESLMYVYEDSAAES--GSGGGGGGGGAGGAGGGCSGASPGKAPSMDGLGGSCPASHCRDLLPHPVLARPPAPLGAPQGAVYTDIPAPEAARQCAPPPAPPTSSSATLGYGYPFGGSYYGCRLS--HNVNLQQKPCAYHPGDKYPEPSGALPGDDLSSRAKEFAFYPSFASSYQAMPGYLDVSVVPGISGHPEPRHDALIPVEGYQHWALSNGWDSQVYCSKEQSQSAHLWKSPFPDVVPLQPEVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKEKKVVSKSK--APHLHST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31276-1", "uniprot_id": "HXC13_HUMAN", "id": "P31276-1", "name": "Homeobox protein Hox-C13", "aln": "MTTSLLLHPRWPESLMYVYEDSAAESGIGGGGGGGGGGTGGAGGGCSGASPGKAPSMDGLGSSCPASHCRDLLPHPVLGRPPAPLGAPQGAVYTDIPAPEAARQCAPPPAPPTSSSATLGYGYPFGGSYYGCRLS--HNVNLQQKPCAYHPGDKYPEPSGALPGDDLSSRAKEFAFYPSFASSYQAMPGYLDVSVVPGISGHPEPRHDALIPVEGYQHWALSNGWDSQVYCSKEQSQSAHLWKSPFPDVVPLQPEVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKEKKVVSKSK--APHLHST", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6JIY4-1", "uniprot_id": "HXCDB_DANRE", "id": "Q6JIY4-1", "name": "Homeobox protein Hox-C13b", "aln": "--------------------------------------------------------MEGLSGNCPASHCRDFISHPALGRHSGSLASHQGTVYPDITTQDAGRQFP---APQASSGTSLGYGYAFGSPYYGCRLSYSHNVNLQQK--SYHPAEKYMETSGALPAEELSSRSKEFAIYPSFASSYQTVPGYLDVPVVPGISAHPESRHEALFPMDSYQHWALSNGWDEQLYCSKEQTHFNHLWKSQFSDVVPHQAEMNGYRRGRKKRVPYTKIQLKELEKEYAASKFITKDRRRRISATTSLSERQVTIWFQNRRVKEKKFVCKSSKSSTNMHSV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:**...********::.**.*.* ...*.: **:**.**.: :*.** . ** :**.::*****.**..******* ******** :***.:** *.*****.::****:****:*********::******.******.***.**:**:*::.***********.*:******:: ***** *.**** *.*:..*************:*****************::********.*******************.*.**. :.::**.", "identical_positions": 191, "similar_positions": 68, "identity": "57.19%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000823-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P31269-1", "uniprot_id": "HXA9_HUMAN", "id": "P31269-1", "name": "Homeobox protein Hox-A9", "aln": "----MATTGALGNYYVDSFLLGADAADELSVGRYAPGTLGQPPRQAATL-AEHPDFSPCSFQSKATVFGAS---------WNPVHAAGANAVPAAVYHHHHHHPYVHPQAPVAAAAPDGRYMRSWLEPTPGALSFAGLPSSRPYGIKPEPLSARRGDCPTLDTHTLS-----LTDYACGSPPVDREKQPSEGAFSENNAENESGGDKPPIDPNN----------------------------------------------------------------------------------------------------------------------------------------PAANWLHAR--------------------------STRKKRCPYTKHQTLEL---EKEFLFNMYLT-------------------------RDR---------RYEVARLLN-LTERQVKIWFQNRR--MKMKKINKDRAKDE----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09631-1", "uniprot_id": "HXA9_MOUSE", "id": "P09631-1", "name": "Homeobox protein Hox-A9", "aln": "----MATTGALGNYYVDSFLLGADAADELGAGRYAPGTLGQPPRQAAAL-AEHPDFSPCSFQSKAAVFGAS---------WNPVHAAGANAVPAAVYHHHHH-PYVHPQAPVAAAAPDGRYMRSWLEPTPGALSFAGLPSSRPYGIKPEPLSARRGDCPTLDTHTLS-----LTDYACGSPPVDREKQPSEGAFSENNAENESGGDKPPIDPNN----------------------------------------------------------------------------------------------------------------------------------------PAANWLHAR--------------------------STRKKRCPYTKHQTLEL---EKEFLFNMYLT-------------------------RDR---------RYEVARLLN-LTERQVKIWFQNRR--MKMKKINKDRAKDE----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZSU5-1", "uniprot_id": "D3ZSU5_RAT", "id": "D3ZSU5-1", "name": "", "aln": "----MATTGALGNYYVDSFLLGADAADELGAGRYAPGALGQPQRQAAAL-AEHPDFSPCSFQSKAAVFGAS---------WNPVHAAGANAVPAAVYHHHHH-PYVHPQAPVAAAAPDGRYMRSWLEPTPGALSFAGLPSSRPYGIKPEPLSARRGDCPTLDTHTLS-----LTDYACGSPPVDREKQPSEGAFSENNAENESGGDKPPIDPSKCL-------------------------------------------------------------------------------------------------------------------------------------LPANRPLPPRRPPGSTS------------------ASAFSRACLRSRWVPLNLGPENQKLVFGTPLIGAPSPENRVDQAGPARGKGGGYCSTRGRGGRASGAETRRPSPKLPRPRTDRLWAVLRKQRREVFCAARLCTNCGSDVSRAI------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9PWL6-1", "uniprot_id": "HXA9A_DANRE", "id": "Q9PWL6-1", "name": "Homeobox protein Hox-A9a", "aln": "----MSTSGALTGYYVDSIVIPGSEETRFSSG------LGLIQHRPTILPADLSDLGPCTFPAKQPVYGTSD--------WGHIPTHFSTGVP-SVYQ-------PHAQPPVVG-----DYVQSWLLDSACGLPQTEPPTVNHNHAKSDTNETNDDGTEYSPHTILQ-----PEVFTNGGCSTKTEAESSRTAEKSGDIEG-----KPGADPEN----------------------------------------------------------------------------------------------------------------------------------------PVSNWLHAS--------------------------STRKKRCPYTKHQILEL---EKEFLFNTYLT-------------------------RDR---------RYEVARLLN-LTERQVKIWFQNRR--MKMKKFNKNETKED----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09087-1", "uniprot_id": "ABDB_DROME", "id": "P09087-1", "name": "Homeobox protein abdominal-B", "aln": "MQQHHLQQQQQQQQQQEQQHLQEQQQHLQQLHHHAHHHLPQPLHTTSHHHSAHPHLQQQQQQQQHAVVASSPSSVLQQQQQQSTPTTHSTPTHAVMYEDPPPVPLVAVQQQHLPAPQQQQQLQQQQQQQQQQLATTPVAGALSPAQTPTGPSAQQQQHLTSPHHQQLPQQQTPNSVASGASSNLQQQQQQQNAAVAPGQTQIVAPTTASVSPSSVSSQKEDINMSIQLAPLHIPAIRAGPGFETDTSAAVKRHTAHWAYNDEGFNQHYGSGYYDRKHMFAYPYPETQFPVGQYWGPNYRPDQTTSAAAAAAYMNEAERHVSAAARQSVEGTSTSSYEPPTYSSPGGLRGYPSENYSSSGASGGLSVGAVGPCTPNPGLHEWTGQVSVRKKRKPYSKFQTLEL---EKEFLFNAYVS-------------------------KQK---------RWELARNLQ-LTERQVKIWFQNRR--MKNKKNSQRQANQQNNNNNSSSNHNHAQATQQHHSGHHLNLSLNMGHHAAKMHQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : . * : .: : ..: : .* .:* : :. . :*. * ::. *. : . .. .:. : *. . : : .. * . .. .*.. * . . *. .: :: *:* :::::*. : : : * .: . *:* : ::** : : .: ", "identical_positions": 19, "similar_positions": 73, "identity": "3.56%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000823-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P31269-1", "uniprot_id": "HXA9_HUMAN", "id": "P31269-1", "name": "Homeobox protein Hox-A9", "aln": "----------------------------------------MATTGALGNYYVDSFLLGADAADELSVGRYAPGTLGQPPRQAATLAEHPD------------------------------------FSPCSFQSKATVFGASWNPVHAAGANAVPAAVYHHHHHHPYVHPQAPVAAAAPDGRYMRSW---------------LEPTPGALSFAGLPSSR------------------------------------PYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPP----------VDREKQPSEGAFSENNAENESGGDKPPIDPNN------------------PAANWLHAR--------------------------STRKKRCPYTKHQTLEL---EKEFLFNMYLT-------------------------RDR---------RYEVARLLN-LTERQVKIWFQNRR--MKMKKINKDRAKDE----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09631-1", "uniprot_id": "HXA9_MOUSE", "id": "P09631-1", "name": "Homeobox protein Hox-A9", "aln": "----------------------------------------MATTGALGNYYVDSFLLGADAADELGAGRYAPGTLGQPPRQAAALAEHPD------------------------------------FSPCSFQSKAAVFGASWNPVHAAGANAVPAAVYHHHHH-PYVHPQAPVAAAAPDGRYMRSW---------------LEPTPGALSFAGLPSSR------------------------------------PYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPP----------VDREKQPSEGAFSENNAENESGGDKPPIDPNN------------------PAANWLHAR--------------------------STRKKRCPYTKHQTLEL---EKEFLFNMYLT-------------------------RDR---------RYEVARLLN-LTERQVKIWFQNRR--MKMKKINKDRAKDE----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZSU5-1", "uniprot_id": "D3ZSU5_RAT", "id": "D3ZSU5-1", "name": "", "aln": "----------------------------------------MATTGALGNYYVDSFLLGADAADELGAGRYAPGALGQPQRQAAALAEHPD------------------------------------FSPCSFQSKAAVFGASWNPVHAAGANAVPAAVYHHHHH-PYVHPQAPVAAAAPDGRYMRSW---------------LEPTPGALSFAGLPSSR------------------------------------PYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPP----------VDREKQPSEGAFSENNAENESGGDKPPIDPSKCL---------------LPANRPLPPRRPPGSTS------------------ASAFSRACLRSRWVPLNLGPENQKLVFGTPLIGAPSPENRVDQAGPARGKGGGYCSTRGRGGRASGAETRRPSPKLPRPRTDRLWAVLRKQRREVFCAARLCTNCGSDVSRAI------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9YGT5-1", "uniprot_id": "HXA9B_DANRE", "id": "Q9YGT5-1", "name": "Homeobox protein Hox-A9b", "aln": "----------------------------------------MSTLGTLS-YYADSHIP--HENDDHLAPRFSSGPVVQQQSRELTLLEYSE------------------------------------QEPYTFQAKSSIFGASWSPVQPTGA----SIAYH-----PYIH--HPCSTGDSDGASVRPWA--------------LEPLP-ALPFTGLSTDT------------------------------------HQDIKLEPLVGS-GECT---THTLLVAETDNNTTQ----------TER-KVPDDAVSNGSHDEKIPAETKLDLDPNN------------------PSSNWLHAK--------------------------STRKKRCPYTKHQTLEL---EKEFLFNMYLS-------------------------RDR---------RYEVARLLN-LTERQVKIWFQNRR--MKMKKCNKDRPKDI----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09087-1", "uniprot_id": "ABDB_DROME", "id": "P09087-1", "name": "Homeobox protein abdominal-B", "aln": "MQQHHLQQQQQQQQQQEQQHLQEQQQHLQQLHHHAHHHLPQPLHTTSHHHSAHPHLQQQQQQQQHAVVASSPSSVLQQQQQQSTPTTHSTPTHAVMYEDPPPVPLVAVQQQHLPAPQQQQQLQQQQQQQQQQLATTPVAGALSPAQTPTGPSAQQQQHLTSPHHQQLPQQQTPNSVASGASSNLQQQQQQQNAAVAPGQTQIVAPTTASVSPSSVSSQKEDINMSIQLAPLHIPAIRAGPGFETDTSAAVKRHTAHWAYNDEGFNQHYGSGYYDRKHMFAYPYPETQFPVGQYWGPNYRPDQTTSAAAAAAYMNEAERHVSAAARQSVEGTSTSSYEPPTYSSPGGLRGYPSENYSSSGASGGLSVGAVGPCTPNPGLHEWTGQVSVRKKRKPYSKFQTLEL---EKEFLFNAYVS-------------------------KQK---------RWELARNLQ-LTERQVKIWFQNRR--MKNKKNSQRQANQQNNNNNSSSNHNHAQATQQHHSGHHLNLSLNMGHHAAKMHQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : ....: . :: . :...: * : : :. . :.:.: ** . .:*. : * :.. . :: : * . ::. :.:.:. : * : *. .* : . . : . . .. . .: .. : :: .. *: . . *. .: :: .*:* :::::*. : : : * .: . *:* : ::** : : .: ", "identical_positions": 19, "similar_positions": 101, "identity": "3.56%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000823-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZM81-1", "uniprot_id": "D3ZM81_RAT", "id": "D3ZM81-1", "name": "", "aln": "MQKATYYDSSAIYGGYPYQAANGFAYNASQQPYAPSATLGTDGVEYHRPACSLQSPASAGAHPKSHELSEACLRTLSGPPSQPPGLGDPPLPPPPPQAAPPAPQPPQPPPQPPAPTPAAPPPPSSVSPPQSANSNPTPASTAKSPLLNSPTVGKQIFPWMKESRQNTKQKTSGSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGG-------YLNSMHSLVNSVPYEPQSPPPFSKPPQGAYGLPPASYPAPLPSCAPPPPPQKRYTAAGSGAGGTPEYDPHAHGLQGNGSYGTPHLQGSPVFV--GGSYVEPMGNSGPALFGLTHLPHTTSAAVDYGGSGPLGSGHHHGPGPGEPHPTYTDLTAHHPSQGRIQEAPKLTHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P02831-1", "uniprot_id": "HXA3_MOUSE", "id": "P02831-1", "name": "Homeobox protein Hox-A3", "aln": "MQKATYYDSSAIYGGYPYQAANGFAYNASQQPYAPSAALGTDGVEYHRPACSLQSPASAGGHPKTHELSEACLRTLSGPPSQPPGLGEPPLPPPPPQAAPPAPQPPQPPPQPPAPTPAAPPPPSSVSPPQSANSNPTPASTAKSPLLNSPTVGKQIFPWMKESRQNTKQKTSGSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGG-------YLNSMHSLVNSVPYEPQSPPPFSKPPQGAYGLPPASYPAPLPSCAPPPPPQKRYTAAGSGAGGTPDYDPHAHGLQGNGSYGTPHLQGSPVFV--GGSYVEPMSNSGP-LFGLTHLPHTTSAAMDYGGTGPLGSGHHHGPGPGEPHPTYTDLTAHHPSQGRIQEAPKLTHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43365-1", "uniprot_id": "HXA3_HUMAN", "id": "O43365-1", "name": "Homeobox protein Hox-A3", "aln": "MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADG-EYHRPACSLQSPSSAGGHPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPPPPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGG-------YLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHIQGSPVFV--GGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGHHHGPGPGEPHPTYTDLTGHHPSQGRIQEAPKLTHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AWZ2-1", "uniprot_id": "HXA3A_DANRE", "id": "Q8AWZ2-1", "name": "Homeobox protein Hox-A3a", "aln": "MQKATYCDGSAIYSGLPYQSANGLGYDASQQQYLQ--ALHAES-EYHRPACSLQSPGISAGLHTSNEMSEVCQQ-INGTQATVTDTSDNKQPP----TAPSGPSSPSSLNQIPNIDSAAKN-PVHVSP--------------------TPSTRKHIFPWMKESRQNTKQKSCSIISVESCAGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGLGMMPSPGAQSP-HSPVSLSSGGGGGGGSAYLSSMHSLVNSVTYDSPSPASYNKPQSNTYSLP-TSYP-PLNNCPPP---QKRYQGTGT---ATPEYD--THHIQGNNNYGT-QVQGSPVYVSGGGGYSDSLVGMGASVFGLTHLPHPSQGNIDYNGAITMGNSHQQGACDSNPC-TFTDLTPHY-SQGRIQEAPKLTHL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****** *.****.* ***:***:.*:*.** * :* ::. ************. :.. .::*:**.* : :... : .. .: * :**..*..*.. * * .** * .** :*:. *:***************:.. * ***********.*:************************************************************** **:.*.*.*** :***. .:** **.*********.*:. **..:.** ..:*.** :*** .* .*.** **** .:*: .**:** :* :***..*** ::*****:* **.* :.: . *. :********.:.. :**.*: .:*..*::*. .:* *:**** *: **************", "identical_positions": 243, "similar_positions": 109, "identity": "53.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000823-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q00056-1", "uniprot_id": "HXA4_HUMAN", "id": "Q00056-1", "name": "Homeobox protein Hox-A4", "aln": "MTMSSFLIN--------------SNYIEPKFPPFEE--------YAQHSGSGGADGGPGGGP---------------------------GYQQPPAPPTQHLPLQQPQLPHAGGGREPTASYYAPRTAREPAYPAAALYPAHGAADTAYPYGYRGGASPGRPPQPEQPPAQAKGPAHGLHASHVLQPQL------------PPPLQPRAVPPAAPRRCEAAPATPGVPAGGSAPACPL--------------------------------------------------------------------LLADKSPLGLKGK----------------------EPVVYPWMKKIHVS-AVNPSYN-GGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNTK-----------------MRSSNSASASAGPPGKAQTQSPHLHPHPHPST-----------STPVPSSI---------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06798-1", "uniprot_id": "HXA4_MOUSE", "id": "P06798-1", "name": "Homeobox protein Hox-A4", "aln": "MTMSSFLIN--------------SNYIEPKFPPFEE--------FAPHGGPGGGDGAVGGGP---------------------------GYPRPQSAP--HLPAPN---PHAA--RQPPA-YYAPR-AREPSYPGG-LYPAP---AAACPYACRG-ASPGRPEQS---------PAPGAHPSPAPQP--------------PVPLG----------HCAPGPTTPAVATGGSAPACPL--------------------------------------------------------------------LLADQGPAGPKGK----------------------EPVVYPWMKKIHVS-AVNSSYN-GGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNTK-----------------MRSSNTASAPAGPPGKAQTHSPHHHPHPLPGA-----------STPIPSSI---------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9PWL5-1", "uniprot_id": "HXA4A_DANRE", "id": "Q9PWL5-1", "name": "Homeobox protein Hox-A4a", "aln": "MIMSSYLIN--------------SNYIEPSFPPCEE--------YHQNG------YMPVSSD---------------------------YYERPKDPG----------FPHHE----------------EASYPRS-NYQEQ-------SYDYGNVSTNDLNDFS---------DRHHAQPQSVSQN-----------------------------HGPRLTTESCVGSDGNKDCS----------------------------------------------------------------------LVSDALPGSQKSK----------------------EPVVYPWMKKVHVN-TVTASYS-GGVPKRSRTAYTRQQALELEKEFHFNRYLTRRRRVEIAHTMCLSERQVKIWFQNRRMKWKKDHKLPNTK-----------------IRSSSSAPSNH----HVKTDATQQQQTLLP--------------TPCSSNL---------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07548-1", "uniprot_id": "DFD_DROME", "id": "P07548-1", "name": "Homeotic protein deformed", "aln": "--MSSFLMGYPHAPHHVQSPMSMGNGLDPKFPPLADDYHHYNGHYSMTASTGHMSGAVGGGAGVGSVGGGGAGGMTGHPHSMHPADMVSDYMAHHHNPHSHSHSHTHSLPHHHSNSAISGHHQASAGGYSSNYANATPPSHPHSHPHAHPHQSLGYYVHHAPEFISAGAVHSDPTNGYGPAANVPNTSNGGGGGGSGAVLGGGAVGGSANGYYGGYGGGYGTANGSVGSTHSQGHSPHSQMMDLPLQCSSTEPPTNTALGLQELGLKLEKRIEEAVPAGQQLQELGMRLRCDDMGSENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKIHVAGVANGSYQPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNKLPNTKNVRKKTVDANGNPTPVAKKPTKRAASKKQQQAQQQQQSQQQQTQQTPVMNECIRSDSLESIGDVSSSLGNPPYIPAAPETTSSYPGSQQHLSNNNNNGSGNNNNNNNNNNSNLNNNNNNNQMGHTNLHGHLQQQQSDLMTNLQLHIKQDYDLTAL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:*:. .* ::*.*** : : . .. * ** .. *. . .: . . . : .: * : . . *: * * .: * ::******:** ... **. * ***.******:* ********:*********:*****: *****:**************:****** :.:. *.: : : .: : : * .*.: ", "identical_positions": 89, "similar_positions": 59, "identity": "15.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000823-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08656-1", "uniprot_id": "HXA1_RAT", "id": "O08656-1", "name": "Homeobox protein Hox-A1", "aln": "-------------MDNARLNSFLEYP-ILGSGDSG-----------TCSARVYSSDHGITTFQS-CAVSANSCGGDDRFLGGRGVQITSP--HHHHHHHHHPQPATYQ---------------------------TSGNLGVSYSHSSCGPSYGAQNFSAPYGPYGLNQEADVSGGYPPCAP------------------------------------------------------------------------------------------AVYSGNLSSPMVQHHHHHQGYAGGTVGSP---QYIHHSYGQ--EHQSLALAT-YNNSLSPLHASHQEACRSP-------------------------------------ASETSSPAQTFDWMKVKRNPPK------------------------------------------TGKVGEYGYVGQP-------------------------------------------NAVRTNFTTKQLTELEKEFHFNKYLTRAR-SEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPMSPATPPGSDEKTEESSEKSSSSP-----------------SAPSPASSTSDTLTTSH-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09022-1", "uniprot_id": "HXA1_MOUSE", "id": "P09022-1", "name": "Homeobox protein Hox-A1", "aln": "------------------MNSFLEYP-ILGSGDSG-----------TCSARAYPSDHGITTFQS-CAVSANSCGGDDRFLVGRGVQISSPHHHHHHHHHHHPQTATYQ---------------------------TSGNLGISYSHSSCGPSYGAQNFSAPYGPYGLNQEADVSGGYPPCAP------------------------------------------------------------------------------------------AVYSGNLSTPMVQHHHHHQGYAGGTVGSP---QYIHHSYGQ--EQQTLALAT-YNNSLSPLHASHQEACRSP-------------------------------------ASETSSPAQTFDWMKVKRNPPK------------------------------------------TGKVGEYGYVGQP-------------------------------------------NAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGSDEKTEESSEKSSPSP-----------------SAPSPASSTSDTLTTSH-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49639-1", "uniprot_id": "HXA1_HUMAN", "id": "P49639-1", "name": "Homeobox protein Hox-A1", "aln": "-------------MDNARMNSFLEYP-ILSSGDSG-----------TCSARAYPSDHRITTFQS-CAVSANSCGGDDRFLVGRGVQIGSP-HHHHHHHHRHPQPATYQ---------------------------TSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALNQEADVSGGYPQCAP------------------------------------------------------------------------------------------AVYSGNLSSPMVQHHHHHQGYAGGAVGSP---QYIHHSYGQ--EHQSLALAT-YNNSLSPLHASHQEACRSP-------------------------------------ASETSSPAQTFDWMKVKRNPPK------------------------------------------TGKVGEYGYLGQP-------------------------------------------NAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDEKAEESSEKSSSSP-----------------CVPSPGSSTSDTLTTSH-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q98SI1-1", "uniprot_id": "HXA1A_DANRE", "id": "Q98SI1-1", "name": "Homeobox protein Hox-A1a", "aln": "------------------MSTFLDFSSISGGGDGGS--------GGSCSVRAFHGDHGLSTFQSSCAVRLNSCSGDERFMSN----ISSQ----DVINSQPQQAGSYQ---------------------------SPGTLSITY---SAHPSYGTQSFCTGYNHYALNQDVESSVSFPQCGP------------------------------------------------------------------------------------------LVYSGNISSTVVQHRHHRHGYSSGNVHLHGQFQYGSATYGNSSDQANLTFVAGCSNPLSPLHVPHHDACCSP-------------------------------------LSDGVPTGQTFDWMKVKRNPPK------------------------------------------TGKAGEYGFGGQP-------------------------------------------NTVRTNFSTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPKSLSEQKDGLEKTEDASEKSPSAP-----------------STPSP-SPTVEAYSSN------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P10105-2", "uniprot_id": "LAB_DROME", "id": "P10105-2", "name": "Homeotic protein labial", "aln": "MMDVSSMYGNHPHHHHPHANAYDGYSTTTASAANASSYFAPQQHQPHLQLQQQQQHQHLQQPQQHLTYNGYESSSPGNYYPQQQAQLTPPPTSSHQVVQQHQQQQQAQQQQLYPHSHLFSPSAAEYGITTSTTTGNPGTPLHPSSHSPADSYYESDSVHSYYATAAVATVAPPSNSSPITAANASATSNTQQQQQQAAIISSENGMMYTNLDCMYPTAQAQAPVHGYAGQIEEKYAAVLHASYAPGMVLEDQDPMMQQATQSQMWHHQQHLAGSYALDAMDSLGMHAHMHHGLPHGHLGNLANNPHQQQPQVQQQQQQPHQQPQHPQNQSPAAHQQHHQNSVSPNGGMNRQQRGGVISPGSSTSSSTSASNGAHPASTQSKSPNHSSSIPTYKWMQLKRNVPKPQAPKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGLGSGSGLSSCSLSSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVKEGLIPADILTQHSTSVISEKPPQQQQPQPPELQLKSQGSDLGGNELATGAPSTPTTAMTLTAPTSKQS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: :. ... .. . : .: : *. : .... .: : . . : * * ..*. . .. . * ::.. : * .: . * . * .. *: : .: * * ::* . * : : . : :: .* .. * *:: . ** .: .. *:.**::*** ** .* *. * * *: ****:.*************:****** *** :********************** ****:* . . :*...::. . * .. :* :.* : ", "identical_positions": 88, "similar_positions": 96, "identity": "13.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000823-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09067-1", "uniprot_id": "HXB5_HUMAN", "id": "P09067-1", "name": "Homeobox protein Hox-B5", "aln": "--------MSSYFVNSFSGRYPNGPDYQLLNYGSG---------------------------SSLSGSYRDPAAMHTGSYGYNYNGMDLSVNRSSASSSHFGAVGE-----------SSRAFPAPAQEPRFRQAASSCSLSSPES-------LPCTNGDSHGAKPSASSPSDQATS-------------ASSSANFTEIDEASASSEPEEAASQLSSPSLARAQPEPMATST-------------------------------------------------------------AAP-EGQTPQIFPWMRKLHISHDMTGP--DGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSLATAGSAFQP------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09079-1", "uniprot_id": "HXB5_MOUSE", "id": "P09079-1", "name": "Homeobox protein Hox-B5", "aln": "--------MSSYFVNSFSGRYPNGPDYQLLNYGSG---------------------------SSLSGSYRDPAAMHTGSYGYNYNGMDLSVNRSSASSSHFGAVGE-----------SSRAFPASAQEPRFRQATSSCSLSSPES-------LPCTNGDSHGAKPSASSPSDQATP-------------ASSSANFTEIDEASASSEPEEAASQLSSPSLARAQPEPMATST-------------------------------------------------------------AAP-EGQTPQIFPWMRKLHISHDMTGP--DGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSLATAGSAFQP------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09013-1", "uniprot_id": "HXB5B_DANRE", "id": "P09013-1", "name": "Homeobox protein Hox-B5b", "aln": "--------MSSYFLNSFSGRYPNGSDYQLLNYGTN---------------------------GAMNASYRDSTSMHSGSFGYNYNGIDLSVNRP--NNGHFGAVGD-----------NSRAFQNPSQETRYRQ--SSCSLSSPDP-------LSCATSDTLELK-GSSPPSDQSTPTGNSRLTNSNNLTSSNSTHFADTDETNVSSETEEGA-QTTTTSHTQKQ-ESVATST-------------------------------------------------------------TTPNDGQTPQIFPWMRKLHISHDMTGP--DGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSLATAGSAFQN------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09077-1", "uniprot_id": "SCR_DROME", "id": "P09077-1", "name": "Homeotic protein Sex combs reduced", "aln": "MDPDCFAMSSYQFVNSLASCYPQQMNPQQNHPGAGNSSAGGSGGGAGGSGGVVPSGGTNGGQGSAGAATPGANDYFPAAAAYTPNLYPNTPQAHYANQAAYGGQGNPDMVDYTQLQPQRLLLQQQQQQQQQQHAHAAAAVAAQQQQQLAQQQHPQQQQQQQQANISCKYANDPVTPGGSGGGGVSGSNNNNNSANSNNNNSQSLASPQDLSTRDISPKLSPSSVVESVARSLNKGVLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGDSDSESDSGNEAGSSQNSGNGKKNPPQIYPWMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKMASMNIVPYHMGPYGHPYHQFDIHPSQFAHLSA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:**::. **: : * : *:. .: ..: .. ...: .*. * : : ... :*. *: . : *: : :: ::.:::: : . : : ... ..* *. ..*:: : :. . :* : .: : :. . *.:* * : . :.***:***:::*:. . ... : ** **:*********************************:*****************::*: **.:.. . ", "identical_positions": 84, "similar_positions": 96, "identity": "20.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000823-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17509-1", "uniprot_id": "HXB6_HUMAN", "id": "P17509-1", "name": "Homeobox protein Hox-B6", "aln": "----------MSSYFVNSTFPVTLASGQESFLG-------QLPLYSSGYADP-------LRHYP-APYGPGPGQDKGFATSSYYPP------AGGGYGR-----------------------------------------------AAPCDYGPAPAFYREKESACALSGA-----DEQPPFHPEPR------------------------------KSDCAQDKSVFGETEEQKCSTPV-------------------------YPWMQRMNSCNSSSFGPS-------------GRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQAE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09023-1", "uniprot_id": "HXB6_MOUSE", "id": "P09023-1", "name": "Homeobox protein Hox-B6", "aln": "----------MSSYFVNSTFPVTLASGQESFLG-------QLPLYSSGYADP-------LRHYP-APYGPGPGQDKGFAASSYYPP------AGGGYGR-----------------------------------------------AAPCDYGPAPAFYREKDAACALSGA-----DEPPPFHPEPR------------------------------KSDCAQDKSVFGETEEQKCSTPV-------------------------YPWMQRMNSCNSSSFGPS-------------GRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKPAE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9YGT4-1", "uniprot_id": "HXB6B_DANRE", "id": "Q9YGT4-1", "name": "Homeobox protein Hox-B6b", "aln": "----------MSSYFVNSTFPVSLPGGQESFLG-------QIPLYSSGYTDS-------LRHYPSATFGATNVQDK-VYTSSYYQQ------AGGVFGRSGS--------------------------------------------TSACDYS-TPNIYRTADRSCAIGSL-----EDSLVLTQDQC------------------------------KTDCTEQGTERYFSTEDKPCTPV-------------------------YPWMQRMNSCNG-MPGST-------------GRRGRQTYTRFQTLELEKEFHFNRYLTRRRRIEISHALCLTERQIKIWFQNRRMKWKKENKAVNSAKVSDEEDGGKAG----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P02833-1", "uniprot_id": "ANTP_DROME", "id": "P02833-1", "name": "Homeotic protein antennapedia", "aln": "MTMSTNNCESMTSYFTNSYMGADMHHGHYPGNGVTDLDAQQMHHYSQNANHQGNMPYPRFPPYDRMPYYNGQGMDQQQQHQVYSRPDSPSSQVGGVMPQAQTNGQLGVPQQQQQQQQQPSQNQQQQQAQQAPQQLQQQLPQVTQQVTHPQQQQQQPVVYASCKLQAAVGGLGMVPEGGSPPLVDQMSGHHMNAQMTLPHHMGHPQAQLGYTDVGVPDVTEVHQNHHNMGMYQQQSGVPPVGAPPQGMMHQGQGPPQMHQGHPGQHTPPSQNPNSQSSGMPSPLYPWMRSQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTKGEPGSGGEGDEITPPNSPQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CY11-1", "uniprot_id": "HMRA1_YEAST", "id": "P0CY11-1", "name": "Silenced mating-type protein A1", "aln": "----------MDDICS---MAENINRTLFNILG--------------------------------------TEIDEINLNTN--------------------------------------------------------------------------NLYN------FIMESN---------------------------------------------LTKVEQHTLHKNISNNR-------------------------------LEIYHHIKKEKS--------------------PKGKSSISPQARAFLEQVFRRKQSLNSKEKEEVAKKCGITPLQVRVWFINKRMRSK-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : : * *: .* : :. :. : :. :. .. :*:.: : **: *: :: *. :.: *::: :* *:::** *:**: * ", "identical_positions": 18, "similar_positions": 39, "identity": "4.76%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000823-8", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V6Z0-1", "uniprot_id": "G3V6Z0_RAT", "id": "G3V6Z0-1", "name": "", "aln": "-------------------------------------------------------------MMDFDERGPCSSNMYLPSCTYYVSGPDFSSLPSFLPQTPSSRPMTYSYSSNLPQVQPVREVTFR-------------------------------EYAIEPATKWHPRGNLAHCYSA---EELVHRDCLQAPSAAGVPGDVLAKSSANVYHHPTP----------------------------AVSSNFYSTVGRNGVLPQAFDQFFETAYGTPENLASSDYPGDKN-----------AEKGPPTAAATSAAAVAAAATGAPATSSSDGGGGGGCQE--AAAEEKERRRRPESSSSPESSSGHTEDKAGGS----------GGQRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINR--------------------DRLQYYSANPLL--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31311-1", "uniprot_id": "HXA11_MOUSE", "id": "P31311-1", "name": "Homeobox protein Hox-A11", "aln": "-------------------------------------------------------------MMDFDERGPCSSNMYLPSCTYYVSGPDFSSLPSFLPQTPSSRPMTYSYSSNLPQVQPVREVTFR-------------------------------EYAIEPATKWHPRGNLAHCYSA---EELVHRDCLQAPSAAGVPGDVLAKSSANVYHHPTP----------------------------AVSSNFYSTVGRNGVLPQAFDQFFETAYGTPENLASSDYPGDKN-----------AEKGPQAAAATSAAAVAAAATGAPATSSSDGGGGGGCQE--AAAEEKERRRRPESSSSPESSSGHTEDKAGGS----------GGQRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINR--------------------DRLQYYSANPLL--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31270-1", "uniprot_id": "HXA11_HUMAN", "id": "P31270-1", "name": "Homeobox protein Hox-A11", "aln": "--------------------------------------------------------------MDFDERGPCSSNMYLPSCTYYVSGPDFSSLPSFLPQTPSSRPMTYSYSSNLPQVQPVREVTFR-------------------------------EYAIEPATKWHPRGNLAHCYSA---EELVHRDCLQAPSAAGVPGDVLAKSSANVYHHPTP----------------------------AVSSNFYSTVGRNGVLPQAFDQFFETAYGTPENLASSDYPGDKS-----------AEKGPPAATATSAAA-AAAATGAPATSSSDSGGGGGCRETAAAAEEKERRRRPESSSSPESSSGHTEDKAGGS----------SGQRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINR--------------------DRLQYYSANPLL--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DDU0-1", "uniprot_id": "HXABA_DANRE", "id": "Q9DDU0-1", "name": "Homeobox protein Hox-A11a", "aln": "-------------------------------------------------------------MMDFDERVSVGSNMYLPSCTYYVPGADFSTLPSFLSQSPSTRPVTYSYASNLPQVQHVREVTFR-------------------------------DYAIDPSTKWPHRGPLAHCYPS---EDSVHKECLPAVTTVG---EMFPKNNASAYYHSTSN--------------------------TTSASNFYGNVGRNGVLPQAFDQFFDTAYGGSDSVVDNDY------------------------AARDKMHSSKQSTPAPAP-----------------EQQPEGKERPETSS-PESSSGNNEEKTSGAN---------SGPRFRKKRCPYTKFQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKMWFQNRRMKEKKLNR--------------------DRLQYYSTNPLL--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09087-1", "uniprot_id": "ABDB_DROME", "id": "P09087-1", "name": "Homeobox protein abdominal-B", "aln": "MQQHHLQQQQQQQQQQEQQHLQEQQQHLQQLHHHAHHHLPQPLHTTSHHHSAHPHLQQQQQQQQHAVVASSPSSVLQQQQQQSTPTTHSTPTHAVMYEDPPPVPLVAVQQQHLPAPQQQQQLQQQQQQQQQQLATTPVAGALSPAQTPTGPSAQQQQHLTSPHHQQLPQQQTPNSVASGASSNLQQQQQQQNAAVAPGQTQIVAPTTASVSPSSVSSQKEDINMSIQLAPLHIPAIRAGPGFETDTSAAVKRHTAHWAYNDEGFNQHYGSGYYDRKHMFAYPYPETQFPVGQYWGPNYRPDQTTSAAAAAAYMNEAERHVSAAARQSVEGTSTSSYEPPTYSSPGGLRGYPSENYSSSGASGGLSVGAVGPCTPNPGLHEWTGQVSVRKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRMKNKKNSQRQANQQNNNNNSSSNHNHAQATQQHHSGHHLNLSLNMGHHAAKMHQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . *.: . .. .. :. :.: : *.. *:. .:** * ::: : :: .* : : .:. .: .: ::: :.. ::.. ..*.. ... :: . ..: . :.*:*.: :.* . : * :* : . *.* .*. * . :*.* . .. . . **** **:*:* ***:**:*..*:.*:** :*:* *:**:****:********:** .: *::* : * ", "identical_positions": 59, "similar_positions": 105, "identity": "11.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000823-9", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52949-1", "uniprot_id": "HXA5_RAT", "id": "P52949-1", "name": "Homeobox protein Hox-A5", "aln": "-----------------------------HNYGDHSSVSEQFRDSASMHSGRYGYG-YNGMDLSVGRSGSG----------------------HFGS-------------------------------GEXXRSYXAGASAAPAEPRYSQPATSTHS-PPPDPLPCSAVAPLPGSD-THHGGKNSLGNSSGCSANCG-----------------------------STHISSREGVG-----TASAAE------------------------------EDAPASSEQAGAQSEPSPAPPAQPQIYPWMRKLHISHDNIGGP-EGKRARTCYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDK----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09021-1", "uniprot_id": "HXA5_MOUSE", "id": "P09021-1", "name": "Homeobox protein Hox-A5", "aln": "-------MSSY-FVNSFCGRYPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYG-YNGMDLSVGRSGSG----------------------HFGS-------------------------------GERARSYAAGASAAPAEPRYSQPATSTHS-PPPDPLPCSAVAPSPGSD-SHHGGKNSLGNSSGASANAG-----------------------------STHISSREGVG-----TASAAE------------------------------EDAPASSEQAGAQSEPSPAPPAQPQIYPWMRKLHISHDNIGGP-EGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSM-----SMAAAGGAFRP-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20719-1", "uniprot_id": "HXA5_HUMAN", "id": "P20719-1", "name": "Homeobox protein Hox-A5", "aln": "-------MSSY-FVNSFCGRYPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYG-YNGMDLSVGRSGSG----------------------HFGS-------------------------------GERARSYAASASAAPAEPRYSQPATSTHS-PQPDPLPCSAVAPSPGSD-SHHGGKNSLSNSSGASADAG-----------------------------STHISSREGVG-----TASGAE------------------------------EDAPASSEQASAQSEPSPAPPAQPQIYPWMRKLHISHDNIGGP-EGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSM-----SMAAAGGAFRP-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9YGT6-1", "uniprot_id": "HXA5A_DANRE", "id": "Q9YGT6-1", "name": "Homeobox protein Hox-A5a", "aln": "-------MSSY-FVNSFCGRYPNGVDYPLHNYGDHNS-SGQCRDSTGMHSGRYACG-YNGMDLSTGHSSPG----------------------HFLSS------------------------------GERTQSYKDSPTATP--VRYNQPVTASSAEPSSDHLPCSSLANSPVSEQSHRALKISLSSTAGSASKSF-----------------------------GTVLS-REGVSK----VSSSME------------------------------EEKPPGSGQTASQN-VSEAP----QIYPWMRKLHISHDNLAGP-EGKRPRTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDNKLKSM-----NMAAAGSGYRP-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09077-1", "uniprot_id": "SCR_DROME", "id": "P09077-1", "name": "Homeotic protein Sex combs reduced", "aln": "MDPDCFAMSSYQFVNSLASCYPQQMNPQQNHPGAGNSSAGGSGGGAGGSGGVVPSGGTNGGQGSAGAATPGANDYFPAAAAYTPNLYPNTPQAHYANQAAYGGQGNPDMVDYTQLQPQRLLLQQQQQQQQQQHAHAAAAVAAQQQQQLAQQQHPQQQQQQQQANISCKYANDPVTPGGSGGGGVSGSNNNNNSANSNNNNSQSLASPQDLSTRDISPKLSPSSVVESVARSLNKGVLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGDSDSESDSGNEAGSSQNSGNGKKNPPQIYPWMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKMASMNIVPYHMGPYGHPYHQFDIHPSQFAHLSA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CY11-1", "uniprot_id": "HMRA1_YEAST", "id": "P0CY11-1", "name": "Silenced mating-type protein A1", "aln": "------------------------------------------------------------------------------------------------------------------------------------MDDICSMAENINRTLFNILGTEIDEINLNTNNLYNFIMESNLTKVEQHTLHKNISNNR---------------------------------------------------------------------------------------------------------------LEIYHHIKKE-----------KSPKGKSSISPQARAFLEQVFRRKQSLNSKEKEEVAKKCGITPLQVRVWFINKRMRSK-------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . ... :** ::: : : ::. : **: *: :: *. :.: *:*: :: *:::** *:**: * ", "identical_positions": 15, "similar_positions": 33, "identity": "3.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000828-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88420-1", "uniprot_id": "SCN8A_RAT", "id": "O88420-1", "name": "Sodium channel protein type 8 subunit alpha", "aln": "--MAARLLAPPGPDSFKPFTPESLANIERRIAESKLK------------------KPPKADGSHREDDEDSKPKPNSDLEAGKSLPF-IYGDIPQGLVAVPLEDFDPYYLTQKTFVVLNRGKTLFRFSATPALYILSPFNLIRRIAIKILIHSVFSMIIMCTILTNCVFMTFSNPPEWSKNVEYTFTGIYTFESLVKIIARGFCIDGFTFLRDPWNWLDFSVIMMAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCVVWPINFNESYLEN-GTRGFDWEEYINNKTNFYMVPGMLEPLLCGNSSDAGQCPEGFQCMK-AGRNPNYGYTSFDTFSWAFLALFRLMTQDYWENLYQLTLRAAGKTYMIFFVLVIFVGSFYLVNLILAVVAMAYEEQNQATLEEAEQKEAEFKAMLEQLKKQQEEAQAAAMATSAGTVSEDAIEEEGEDGVGSPRSSSELSKLSSKSAKERRNRRKKRKQKELSEGEEKGDPEKVFKSESEDGMRRKAFRLPDNRIGRKFSIMNQSLLSIPGSPFLSRHNSKSS-IFSFR-GPGRFRDPGSENE---------------FADDEHSTVEESE--------------GRRDSLFIPIRARERRSSYSGYSGYSQCSRSSRIF--PSLRRSVKRNSTVDCNG-------VVSLIG-PGSHIG-RLLPEA-----------TTEVEIKKKGPGSLLVSMDQL-ASYGRKDRINSIMSVVTNTLVEELEES----QRKCPPCWYKFANTFLIWECHPYWIKLKEIVNLIVMDPFVDLAITICIVLNTLFMAMEHHPMTPQFEHVLAVGNLVFTGIFTAEMFLKLIAMDPYYYFQEGWNIFDGFIVSLSLMELSLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKINQECKLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLIVFMMVMVIGNLVVLNLFLALLLSSFSADNLAATDDDGEMNNLQISVIRIKKGVAWTKVKVHAFMQAHFKQRE-----------ADEVKPLDELYEKKANCIANHTG-VDIHRNGDFQKNGNGTTSGIGSSVEKYIIDEDHMSFINNPNLTVRVP------IAVGESDFENLNTEDVSS-----ESDPEGSKDKLDDTSSSEGSTIDIKPEVEEVP-VEQPEEYLD----------------PDACFTEGCVQRFKCCQVNIEEGLGKSWWILRKTCFLIVEHNWFETFIIFMILLSSGALAFEDIYIEQRKTIRTILEYADKVFTYIFILEMLLKWTAYGFVKFFTNAWCWLDFLIVAVSLVSLIANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKYHYCFNETSEIRFEIDIVNNKTDCEKLMEGNSTEIRWKNVKINFDNVGAGYLALLQVATFKGWMDIMYAAVDSRKPDEQPDYEGNIYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGG-QDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKIQGIVFDFVTQQAFDIVIMMLICLNMVTMMVETDTQSKQMENILYWINLVFVIFFTCECVLKMFALRHYYFTIGWNIFDFVVVILSIVGMFLADIIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIFSIFGMSNFAYVKHEAGIDDMFNFETFGNSMICLFQITTSAGWDGLLLPILNRPPDCSLDKEHPGSGFKGDCGNPSVGIFFFVSYIIISFLIVVNMYIAIILENFSVATEESADPLSEDDFETFYEIWEKFDPDATQFIEYCKLADFADALEHPLRVPKPNTIELIAMDLPMVSGDRIHCLDILFAFTKRVLGDSGELDILRQQMEERFVASNPSKVSYEPITTTLRRKQEEVSAVVLQRAYRGHLAR--------------------RGFICRKMASN-KLENGG------THRDKKESTPSTASLPSYDSVTKPDKEKQQRAEEGRRERA----------------------KRQKEVRESKC----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTU3-1", "uniprot_id": "SCN8A_MOUSE", "id": "Q9WTU3-1", "name": "Sodium channel protein type 8 subunit alpha", "aln": "--MAARVLAPPGPDSFKPFTPESLANIERRIAESKLK------------------KPPKADGSHREDDEDSKPKPNSDLEAGKSLPF-IYGDIPQGLVAVPLEDFDPYYLTQKTFVVLNRGKTLFRFSATPALYILSPFNLIRRIAIKILIHSVFSMIIMCTILTNCVFMTFSNPPEWSKNVEYTFTGIYTFESLVKIIARGFCIDGFTFLRDPWNWLDFSVIMMAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCVVWPINFNESYLEN-GTRGFDWEEYINNKTNFYMVPGMLEPLLCGNSSDAGQCPEGFQCMK-AGRNPNYGYTSFDTFSWAFLALFRLMTQDYWENLYQLTLRAAGKTYMIFFVLVIFVGSFYLVNLILAVVAMAYEEQNQATLEEAEQKEAEFKAMLEQLKKQQEEAQAAAMATSAGTVSEDAIEEEGEDGVGSPRSSSELSKLSSKSAKERRNRRKKRKQKELSEGEEKGDPEKVFKSESEDGMRRKAFRLPDNRIGRKFSIMNQSLLSIPGSPFLSRHNSKSS-IFSFR-GPGRFRDPGSENE---------------FADDEHSTVEESE--------------GRRDSLFIPIRARERRSSYSGYSGYSQCSRSSRIF--PSLRRSVKRNSTVDCNG-------VVSLIG-PGSHIG-RLLPEA-----------TTEVEIKKKGPGSLLVSMEQL-ASYGRKDRINSIMSVVTNTLVEELEES----QRKCPPCWYKFANTFLIWECHPYWIKLKEIVNLIVMDPFVDLAITICIVLNTLFMAMEHHPMTPQFEHVLAVGNLVFTGIFTAEMFLKLIAMDPYYYFQEGWNIFDGFIVSLSLMELGLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKISQECKLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLIVFMMVMVIGNLVVLNLFLALLLSSFSADNLAATDDDGEMNNLQISVIRIKKGVAWAKVKVHAFMQAHFKQRE-----------ADEVKPLDELYEKKANCIANHTG-VDIHRNGDFQKNGNGTTSGIGSSVEKYIIDEDHMSFINNPNLTVRVP------IAVGESDFENLNTEDVSS-----ESDPEGSKDKLDDTSSSEGSTIDIKPEVEEVP-VEQPEEYLD----------------PDACFTEGCVQRFKCCQVNIEEGLGKSWWILRKTCFLIVEHNWFETFIIFMILLSSGALAFEDIYIEQRKTIRTILEYADKVFTYIFILEMLLKWTAYGFVKFFTNAWCWLDFLIVAVSLVSLIANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKYHYCFNETSEIRFEIDEVNNKTDCEKLMEGNNTEIRWKNVKINFDNVGAGYLALLQVATFKGWMDIMYAAVDSRKPDEQPDYEGNIYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGG-QDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKIQGIVFDFVTQQAFDIVIMMLICLNMVTMMVETDTQSKQMENILYWINLVFVIFFTCECVLKMFALRHYYFTIGWNIFDFVVVILSIVGMFLADIIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIFSIFGMSNFAYVKHEAGIDDMFNFETFGNSMICLFQITTSAGWDGLLLPILNRPPDCSLDKEHPGSGFKGDCGNPSVGIFFFVSYIIISFLIVVNMYIAIILENFSVATEESADPLSEDDFETFYEIWEKFDPDATQFIEYCKLADFADALEHPLRVPKPNTIELIAMDLPMVSGDRIHCLDILFAFTKRVLGDSGELDILRQQMEERFVASNPSKVSYEPITTTLRRKQEEVSAVVLQRAYRGHLAR--------------------RGFICRKITSN-KLENGG------THREKKESTPSTASLPSYDSVTKPDKEKQQRAEEGRRERA----------------------KRQKEVRESKC----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQD0-1", "uniprot_id": "SCN8A_HUMAN", "id": "Q9UQD0-1", "name": "Sodium channel protein type 8 subunit alpha", "aln": "--MAARLLAPPGPDSFKPFTPESLANIERRIAESKLK------------------KPPKADGSHREDDEDSKPKPNSDLEAGKSLPF-IYGDIPQGLVAVPLEDFDPYYLTQKTFVVLNRGKTLFRFSATPALYILSPFNLIRRIAIKILIHSVFSMIIMCTILTNCVFMTFSNPPDWSKNVEYTFTGIYTFESLVKIIARGFCIDGFTFLRDPWNWLDFSVIMMAYITEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCVVWPINFNESYLEN-GTKGFDWEEYINNKTNFYTVPGMLEPLLCGNSSDAGQCPEGYQCMK-AGRNPNYGYTSFDTFSWAFLALFRLMTQDYWENLYQLTLRAAGKTYMIFFVLVIFVGSFYLVNLILAVVAMAYEEQNQATLEEAEQKEAEFKAMLEQLKKQQEEAQAAAMATSAGTVSEDAIEEEGEEGGGSPRSSSEISKLSSKSAKERRNRRKKRKQKELSEGEEKGDPEKVFKSESEDGMRRKAFRLPDNRIGRKFSIMNQSLLSIPGSPFLSRHNSKSS-IFSFR-GPGRFRDPGSENE---------------FADDEHSTVEESE--------------GRRDSLFIPIRARERRSSYSGYSGYSQGSRSSRIF--PSLRRSVKRNSTVDCNG-------VVSLIGGPGSHIGGRLLPEA-----------TTEVEIKKKGPGSLLVSMDQL-ASYGRKDRINSIMSVVTNTLVEELEES----QRKCPPCWYKFANTFLIWECHPYWIKLKEIVNLIVMDPFVDLAITICIVLNTLFMAMEHHPMTPQFEHVLAVGNLVFTGIFTAEMFLKLIAMDPYYYFQEGWNIFDGFIVSLSLMELSLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKINQDCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLIVFMMVMVIGNLVVLNLFLALLLSSFSADNLAATDDDGEMNNLQISVIRIKKGVAWTKLKVHAFMQAHFKQRE-----------ADEVKPLDELYEKKANCIANHTG-ADIHRNGDFQKNGNGTTSGIGSSVEKYIIDEDHMSFINNPNLTVRVP------IAVGESDFENLNTEDVSS-----ESDPEGSKDKLDDTSSSEGSTIDIKPEVEEVP-VEQPEEYLD----------------PDACFTEGCVQRFKCCQVNIEEGLGKSWWILRKTCFLIVEHNWFETFIIFMILLSSGALAFEDIYIEQRKTIRTILEYADKVFTYIFILEMLLKWTAYGFVKFFTNAWCWLDFLIVAVSLVSLIANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKYHYCFNETSEIRFEIEDVNNKTECEKLMEGNNTEIRWKNVKINFDNVGAGYLALLQVATFKGWMDIMYAAVDSRKPDEQPKYEDNIYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGG-QDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKIQGIVFDFVTQQAFDIVIMMLICLNMVTMMVETDTQSKQMENILYWINLVFVIFFTCECVLKMFALRHYYFTIGWNIFDFVVVILSIVGMFLADIIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIFSIFGMSNFAYVKHEAGIDDMFNFETFGNSMICLFQITTSAGWDGLLLPILNRPPDCSLDKEHPGSGFKGDCGNPSVGIFFFVSYIIISFLIVVNMYIAIILENFSVATEESADPLSEDDFETFYEIWEKFDPDATQFIEYCKLADFADALEHPLRVPKPNTIELIAMDLPMVSGDRIHCLDILFAFTKRVLGDSGELDILRQQMEERFVASNPSKVSYEPITTTLRRKQEEVSAVVLQRAYRGHLAR--------------------RGFICKKTTSN-KLENGG------THREKKESTPSTASLPSYDSVTKPEKEKQQRAEEGRRERA----------------------KRQKEVRESKC----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PT64-1", "uniprot_id": "A0A8M9PT64_DANRE", "id": "A0A8M9PT64-1", "name": "Sodium channel protein", "aln": "--MAAPLLAPPGPNSYKYFTRESLREIEKRIEEEKAK------------------PPPKPDNSYRDDDDENKPKPNGDLEAGKSLPF-IYGDIPPGMVATPLEDFDPFYINQKTFVVLNKGKTIFRFSATPALYMISPFNLARRIAIKILIHSVFSMFIMCTILTNCVFMTFSNPPEWSKQVEYTFTGIYTFESAVKIIARGFCIDGFTFLRDPWNWLDFMVISMAYITEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRQKCVIWPINITEMFPDVNGSRAFNWDEYILNETNFYFLPDQLDALLCGNSSDSGRCPEGYTCMK-AGRNPNYGYTSFDSFGWAFLALFRLMTQDFWENLYQLTLRAAGKTYMIFFVLVIFVGSFYLVNLILAVVAMAYEEQNQATMEEAERKEAEFKAMLEQLKKQQEDAQANAMATSAGTVSEDVVEDDGDGEGNLSCSSSEMSKLSSKSAKERRNRKKKWRQKEQD--KEKGDSEKFVKSESDDGSRRR-FRFPDNRLGRRSSIMNQSLLSIPGSPFPSRRNSKSS-IFS------RCKDGGSENE---------------FADDEHSTVEEYD--------------ERRDSFLSPQ----RRSSYTGFYG--------------------KRNSTVDCNG-------VVSLIG---PGPGGRLLPEVIIDKAATDDSPTTDLEIKKKLSGSLMVSVEQLNTSFGRKERANSVMSALTNTLVEELEES----QRKCPPCWYKFANTFLIWECGPLWMSIKEIVNLIVMDPFVDLAITICIVLNTLFMAMEHYPMTPQFEHVLSVGNLVFTGIFTAEMFAKLVAMDPYYYFQEGWNIFDGFIVSLSLMELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKDCVCKIAQDCELPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLIVFMMVMVIGNLVVLNLFLALLLSSFSADNLAASDDDGEMNNLQIAVIRIKKGIAWVKAKVRELVNIILGRKV-----------TDEAKPLDDMYDRKLNCIANHTG-VDISRDLDYQKNGNGTTSGIGSSVGKYMIDDDHMSFIHNPNLTVCVP------IAVGESDFENLNTEDFSS-----ESEAEGSKE-LDDISSSEGSTIDIKPEVEEAVVVETVEEYVD----------------PEACWTEACIARYKCCDVPITEGWGKNWWFLRKTCYLIVEHNWFETLIIFMILLSSGALAFEDVYIEQRKTIRIILEYADMVFTYIFILEMLLKWVAYGFVKYFTNAWCWLDFFIVDVSIVSLIANALGYSDLGPIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNMFAGKYYYCYNETEKAYFELDVVNNKSECFALIEQNYTEVRWKNVKINFDNVGAGYLALLQVATFKGWMDIMYAAVDSRRVEDQPKYEDNIYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGG-QDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPQNKLQGMVFDFVTQQVFDISIMILICLNMVTMMVETDDQSQETENILYWINFIFIVAFTSEFVLKLFALRHYYFTNGWNIFDCVVVILSIVGMFLADLIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIFSIFGMSNFAYVKRESGIDDMYNFETFGNSMICLFMITTSAGWDGLLAPILNYPPDCEPTKENPGTSVKGNCGNPSVGIFFFVMYIIVSFLIVVNMYIAIILENFSVATEESADPLCEDDFESFYEIWEKFDPTASQFITFAKLGDFADTLEHPLRVPKPNTIELIAMDLPMVSGDRIHCLDILFAFTKRVLGDSGDLDMMRQQMEERFIAANPSKVSFEPITTTLRRKQEHMSAGVIQRAFRAHLIR--------------------KGFICKRLLSSSRLENGG------TNQDKKEGTPSTASLPSYDSVTKPEKEKLEESD-SKGKKG----------------------KNQKDVKESKF----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35500-1", "uniprot_id": "SCNA_DROME", "id": "P35500-1", "name": "Sodium channel protein para", "aln": "MTEDSDSISEEERSLFRPFTRESLVQIEQRIAAEHEKQKELERKRAEGEVPQYGRKKKQKEIRYDDEDEDEGPQPDPTLEQGVPIPVRLQGSFPPELASTPLEDIDPYYSNVLTFVVVSKGKDIFRFSASKAMWMLDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTP-TVESTEVIFTGIYTFESAVKVMARGFILCPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCIKK-FPLDGSWGNL---TDENWDYHNRNSSNWYSEDEGISFPLCGNISGAGQCDDDYVCLQGFGPNPNYGYTSFDSFGWAFLSAFRLMTQDFWEDLYQLVLRAAGPWHMLFFIVIIFLGSFYLVNLILAIVAMSYDELQKKAEEEEAAEEEAIREAEEAAAAKAAKLEERANAQAQAAADAAAAEEAALHPEMAKSPTYSCISYELFVGGEKGNDDNNKEKMSIRSVEVESESVSVIQRQPAP---------TTAHQATKVRKVSTTSLSLPGSPFNIRRGSRSSHKYTIRNGRGRFGIPGSDRKPLVLSTYQDAQQHLPYADDSNAVTPMSEENGAIIVPVYYGNLGSRHSSYTSHQSRISYTSHGDLLGGMAVMGVSTMTKESKLRNRNTRNQSVGATNGGTTCLDTNHKLDHRDYEIGLECTDEAGKIKHHDNPFIEPVQTQTVVDMKDVMVLNDIIEQAAGRHSRASDRGVSVYYFPTEDDDEDGPTFKDKALEVILKGIDVFCVWDCCWVWLKFQEWVSLIVFDPFVELFITLCIVVNTMFMAMDHHDMNKEMERVLKSGNYFFTATFAIEATMKLMAMSPKYYFQEGWNIFDFIIVALSLLELGLEGVQGLSVLRSFRLLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYHDHKDRFP-DGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMYVG-DVSCIPFFLATVVIGNLVVLNLFLALLLSNFGSSSLSAPTADNDTNKIAEAFNRIGRFKSWVKRNIADCFKLIRNKLTNQISDQPSGERTNQISWIWSEGKGVCRCISAEHGDNELELGHDEILADGLIKKGIKEQTQLEVAIGDGMEFTIHGDMKNNKPKKSKYLNNATDDDTASINSYGSHKNRPFKDESHKGSAETMEGEEKRDASKEDLGLDEELDEEGECEEGPLDGDIIIHAHDEDILDEYPADCCPDSYYKKFPILAGDDDSPFWQGWGNLRLKTFQLIENKYFETAVITMILMSSLALALEDVHLPQRPILQDILYYMDRIFTVIFFLEMLIKWLALGFKVYFTNAWCWLDFVIVMVSLINFVASLVGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCEDMN-GTKLSHEIIPNRNACE------SENYTWVNSAMNFDHVGNAYLCLFQVATFKGWIQIMNDAIDSREVDKQPIRETNIYMYLYFVFFIIFGSFFTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDIIIMLFIGLNMFTMTLDRYDASDTYNAVLDYLNAIFVVIFSSECLLKIFALRYHYFIEPWNLFDVVVVILSILGLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKEKSGINDVYNFKTFGQSMILLFQMSTSAGWDGVLDAIIN-EEACDPPDNDKG--YPGNCGSATVGITFLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQQFDPEGTQYIRYDQLSEFLDVLEPPLQIHKPNKYKIISMDIPICRGDLMYCVDILDALTKDFFARKG--NPIEETGEIGEIAARPDTEGYEPVSSTLWRQREEYCARLIQHAWRKHKARGEGGGSFEPDTDHGDGGDPDAGDPAPDEATDGDAPAGGDGSVNGTAEGAADADESNVNSPGEDAAAAAAAAAAAAAAGTTTAGSPGAGSAGRQTAVLVESDGFVTKNGHKVVIHSRSPSITSRTADV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: . :: ** *** :**:** .: * : : : ::*::. *:*: ** * .:*. : *.:* :.:.****:**:* . ****:.:** :*****: *::::.*** **:** **:*.:**::*: ***.**::* :...* :..* ********* **::**** : **:***.****** ** :**:* ::***::*************::::*********:*:***:* **:***:*.******:***::** * :**: : : : : :*: : *.:*:* :. **** *.:*:* :.: *:: * **********:*.****: *******:**:****.***** :*:**:::**:***********:***:*:* :: : ** :* :: * : . : * * : .:.. . *: . .: . . . . *: * :: .: . : :.:. ...: :. . : . : :. : **:***** *:.*:** :: * **:.: :***.::.. : *.* . :*: . * .**.:*.... . :. * . *. . . .::* : : : **:.* .. : .*: :*. : *. * :.* :*:* *:.::* *.***:****:* **:***:**:****:*: *. ::*:** ** .**. *: * **:**.* *********** :**:***:**.* .*:************************:**.*:*.::*******:**.**:*****:*******.*:: :: : .****:: **:***:************:***** *. :. *: .*: .:*****************.*.:..*:*. *.: *:: :. ** : :*.* :: .: : ::: . : . . .**: . * :: . * .. ..** ... : * *.* : ::. * . :.* .:*: . . :.. :** : ::. .. :.*. *: : * * * :* * * .:. :: . :.* ** . : ::*:::*** :* ***:** ***:**::: ** :: ** * * :** **:****:** * ** :**********.** **::.::*. :* . : .:*::***********:**::********** *****:*************:****::*****. * : . :. : : *:. * : * * :***:** .**.*:********::** *:***. :.** * *****:***:**********************:**** ** ::****:**********:***** *.**** : *.:**::**:: *** **::* ***.** :: *. : :* ::* :*:: *:.* :**:****::** **:** *******:*:.*:*:**********:**:*:*::**:***:************* ********* **********:***** * :**.::**:*::**:***:*** ** ::*******:* .*:* *. .:. * *:**..:*** *:: *:::*****:*****:****:* ***: : * :**:: :****::*** .:*:* : :*.:* *.** **:: ***. ::*:**:*: ** ::*:*** *:** .:. .* : :.: * :*:.*.. .:**:::** *::*. .* ::*:*:* * * * . :. ** * . :. *... *. *:.: . : . : :* * .*: ", "identical_positions": 849, "similar_positions": 573, "identity": "39.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000831-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q05920-1", "uniprot_id": "PYC_MOUSE", "id": "Q05920-1", "name": "Pyruvate carboxylase, mitochondrial", "aln": "-MLKFQTVRGGLRLLGVRRS-SSAPVASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELGIRTVAVYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENGVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDSPISSLHEAHEFSNTFGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPATHLDPQLRSRLTSDSVKLAKQVGYENAGTVEFLVDKHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVSEGRSLPDLGLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIPFLQNVLNNQQFLAGTVDTQFIDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVNVSPSPVDPAVPVVPIGPPPAGFRDILLREGPEGFARAVRNHQGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFNKLFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVFKFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSLEYYMGLAEELVRAGTHILCIKDMAGLLKPAACTMLVSSLRDRFPDLPLHIHTHDTSGAGVAAMLACAQAGADVVDVAVDSMSGMTSQPSMGALVACTKGTPLDTEVPLERVFDYSEYWEGARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQMLGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGIPHGGFPEPFRSKVLKDLPRIEGRPGASLPPLNLKELEKDLIDRHGEEVTPEDVLSAAMYPDVFAQFKDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFELNGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVAAGDKVAKGQPLCVLSAMKMETVVTSPMEGTIRKVHVTKDMTLEGDDLILEIE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11498-1", "uniprot_id": "PYC_HUMAN", "id": "P11498-1", "name": "Pyruvate carboxylase, mitochondrial", "aln": "-MLKFRTVHGGLRLLGIRRT-STAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELGIRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDLGLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQFIDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAGFRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSKLFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVFKFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSLQYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGVAAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEGARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQMLGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFPEPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHFKDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFELNGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVLSAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QYZ6-1", "uniprot_id": "F1QYZ6_DANRE", "id": "F1QYZ6-1", "name": "Pyruvate carboxylase", "aln": "MLLHLGGSRAKTGILFIRRAGLFCRSAHLSSQTLEYHPIKKVMVANRGEIAIRVFRACTELGIRTVAVYSEQDTGQMHRQKADEAYLIGRGLSPVAAYLHIPDIIKVAKENNVDAIHPGYGFLSERADFAQACAEAGVRFIGPSPEVVRKMGDKVEARALAIKAGVPVVPGTDAPISCLQEAQEFAKTYDFPIIFKAAYGGGGRGMRVVRNYEELEENYQRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDKYGNVIHLYERDCSIQRRHQKVVEIAPAAHLDSHLRDRLTLDSVNLAKQVGYENAGTVEFLVDKHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQLRVCEGRSLPELGLEQDKIQINGCAIQCRVTTEDPSRGFQPDTGRIEVFRSGEGMGIRLDSASAFQGAIISPHYDSLLVKVIASGKDLPTAATKMHRALTEFRVRGVKTNIPFLQNVLSNSQFLYATVDTQFIDENQNLFNLKPTQNRAQKLLHYLGHVMVNGPMTPIPVKAKPSPVDPVIPSVSLGEPPLGFREVLLREGPEGFARAIRQHQGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVSHNFSNLFSLENWGGATFDVAMRFLSECPWKRLQELRALIPNVPFQMLLRGANAVGYTNYPDNAVFKFCEVAKENGMDIFRVFDSLNYIPNMLLGMEAAGAAGGVVEAAISYTGDVSDPMRQKYSLDYYLKLADELVKAGTHILSIKDMAGLLKPQASRLLIEALRDRFPDIPIHVHTHDTAGAGVAAMLACAQAGADIVDVAVDSMAGMTSQPSMGAIVACTKGTKLDTGISLDKVFDYSEYWEVARGLYAPFDCTATMKSGNADVYENEIPGGQYTNLHFQAHSMGLGNKFKEVKKAYTEANKLLGDLIKVTPSSKIVGDLAQFMVQNSLSLAEVEKRADELSFPLSVVEFLQGHIGIPHGGFPEPFRSKVLKSLPRIEGRPGASLPPMDFEALESGLRAAHGDEITPEDVMSAAMYPKVFQEFKEFTSTFGPVDCLNTRLFLDGPKIAEEFQVELERGKILHIKALALGDLNKSGQREVFFELNGQLRSVLVKDTAAMKEMHFHPKALKDVRGQVGAPMPGKVVEVKVKAGQKVEKGQPLCVLSAMKMETVVNSPISGIISKVHVNADSSLEGEDLILEITE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:: :. :* :**: . * . : ***:******************************:************************:** ***************.***:***************** :************************:** **********:**:.*:**:**::*:.*******************:.******** **********************************:***::**********************:***.:** *** ***:******************:********************************::*.******:***.*::*:***************:*.**********************.*******:************** *** ******* ***:***********.******.*.*** .********** :**:*:*:******************* *****:..***.**.:* *.:* ** ***::************:*:* *********************************:***.:***:*************** ****:****** ****:********************.**************:*********:***********:***************:** * ****:**: **:***:******.********** *. :*:.:*******:*:*:*****:****************:****.***:**********:****:** *** :.:::********* ******.***********:*************************.*********.***::************************.** **.* :*:***** ********:**:***************.***:**********:::: **. * **:*:*****:******.** .**:**:****:*.*******:********:******* *******:.***::***:***********:***** ***************:**:********:::** ** ** *****************.**:.* : ****. * :***:****** ", "identical_positions": 965, "similar_positions": 153, "identity": "81.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000831-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08195-2", "uniprot_id": "4F2_HUMAN", "id": "P08195-2", "name": "Amino acid transporter heavy chain SLC3A2", "aln": "MSQDTEVDMKEVELNELEPEKQPMNAASGAAMSLAGAEKNGLVKIKVAEDEAEAAAAAKFTGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPAQKWWHTGALYRIGDLQAFQGHGAGNLAGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNYRGENSWFS-TQVDTVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNITKGFSEDRLLIAGTNSSDLQQILSLLESNKDLLLTSSYLSDSGSTGEHTKSLVTQYLNATGNRWCSWSLSQ-ARLLTSFLPAQLLRLYQLMLFTLPGTPVFSYGDEIGLDAAALPGQPMEAPVMLWDESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGPGLFSYIRHWDQNERFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLLSTQPGR---EEGSPLELERLKLEPHEGLLLRFPYAA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10852-1", "uniprot_id": "4F2_MOUSE", "id": "P10852-1", "name": "Amino acid transporter heavy chain SLC3A2", "aln": "MSQDTEVDMKDVELNELEPEKQPMNAADGAAA----GEKNGLVKIKVAEDETEAG--VKFTGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPVQRWWHKGALYRIGDLQAFVGRDAGGIAGLKSHLEYLSTLKVKGLVLGPIHKNQKDEINETDLKQINPTLGSQEDFKDLLQSAKKKSIHIILDLTPNYQGQNAWFLPAQADIVATKMKEALSSWLQDGVDGFQFRDVGKLMNAPLYLAEWQNITKNLSEDRLLIAGTESSDLQQIVNILESTSDLLLTSSYLSNSTFTGERTESLVTRFLNATGSQWCSWSVSQ-AGLLADFIPDHLLRLYQLLLFTLPGTPVFSYGDELGLQG-ALPGQPAKAPLMPWNESSIFHIPRPVSLNMTVKGQNEDPGSLLTQFRRLSDLRGKERSLLHGDFHALSSSPDLFSYIRHWDQNERYLVVLNFRDSGRSARLGASNLPAGISLPASAKLLLSTDSARQSREEDTSLKLENLSLNPYEGLLLQFPFVA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QSI9-1", "uniprot_id": "F1QSI9_DANRE", "id": "F1QSI9-1", "name": "", "aln": "--MNKEDEMKEVELNEMDQEKQPMTGETPTGT-----EKNGSVKVKVPEDA-----EVKFTGLSKEELMKVAGTAGWVRTRWALLVLFWLGWVGMLAGAIVIIVQAPRCKPIPEMHWWNEGPLYQISNLDAFS---KNGLKGVEEKLDYLSQMKVKGLVLGPVHSVQADQSSALELTSINPDFGSESELTSLLDRAHRKGISIVLDLTPNYRGVSSWFN--NAASVAEKLKKACVYWLNKGVDGIFLSDLNDIVNTYAWSSIQAIFNKTDGTPKKALMGTASSLSVDETSLLLNQSGVDLLLTKLPYPAGLSGRQATLMQRLCSGHQEASLGWGLGQTAGSQASRTPALPVKLYQTLLFALPGTPVFSAGDELGLKA----------GEAMWED-----------VNSTAE---EERTAVRNFFKTLSDLKGKERSLLHGEYVNLHNSPTSLAFLRLWDQSERFMVAVNWGNDSISMTPTNDDLPAEARVRATTDIEKLA--------VDSKVKLEKLELGSKQAVLLSYPFPG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* :**:*****:: *****.. :. **** **:**.** .**********:****:.**********:******:******:****:****: :* :**: *.**:*.:*:** ..: *:: :*:*** :*********:*. * *: :* .*:* :**:.:: .**: *::*.* ::*******:* .:** :. ** *:*.* **: ****: . *: .: :: : : :.* . : : ** ** : .:* . ..: * : *. . . : :*: : .. . .*.:.* * :. * ::*** :**:******** ***:**.. *:: * *.: *: :: . *: *** :.********:: : .* ::::* ***.**::*.:*: : . * .:*** : *.:.: : .: ::**.*.* . :.:** :*: .", "identical_positions": 194, "similar_positions": 156, "identity": "36.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000831-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q13217-1", "uniprot_id": "DNJC3_HUMAN", "id": "Q13217-1", "name": "DnaJ homolog subfamily C member 3", "aln": "--MVAPGSVTSRLGSVFP---FLLVLVDLQYEGAEC-GVNADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRLRSQALNAFGSGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPEMRKKFDDGEDPLDAESQQGGGGNPFHRSWNSWQGFNPFSSGGPFRFKFHFN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91YW3-1", "uniprot_id": "DNJC3_MOUSE", "id": "Q91YW3-1", "name": "DnaJ homolog subfamily C member 3", "aln": "--MVAPGSVGSRLGAVFP---FLLVLVDLQYEGAEC-GVNADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIALKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSEQEEKEAESQLVKADEMQRLRSQALDAFDGADYTAAITFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKSDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSVAEYTVRSKERICHCFSKDEKPVEAIRICSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYEAAQEHNENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPEMRKKFDDGEDPLDAESQQGGGGNPFHRSWNSWQGFNPFSSGGPFRFKFHFN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1P8N0-1", "uniprot_id": "A0A8M1P8N0_DANRE", "id": "A0A8M1P8N0-1", "name": "DnaJ homolog subfamily C member 3", "aln": "MTIIMESGRRRGLNSVLSSLSLLCVVLDLQLDGVLG-ATPVEIEHHLEMGRKLLAAGQLAEALSHYHSAVEGDSKNYLTYYKRATVFLAMGKSKSALPDLTQAIQLKPDFLAARLQRGNILLKQGSTQEAREDFQAVLNHSP---DHEEAHDQLLKADKLESLQEEAHEAHRRGDCRIAVQVLEHVIELSPWDPESRELRAECYIQLGEPRKAIMDLTPASRLRADNRAAFLKLSQLHYSLGEHHDSLNQVRECLKLDQDDKECFALYKQVKKLSKQLDSAEELISEQRFQEAIEKYESVMRTEPNVAFYTNKAKERTCFCLVKMKSAEEAVDICSEAHQREPQNIHILRDRAEAYILMQEYEKAVEDYQEAREFDQENQELREGLDRAHKLLKISRKRDYYKILGVSRSANKQEIIKAYRKLAQQWHPDNFQSEADKKEAEKKFIDIASAKEVLTDPEMRQKFDSGEDPLDPENQQGGGGG-GPREWP--FGFNPFE-GGNFHFKFNFN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHA8-1", "uniprot_id": "Q9VHA8_DROME", "id": "Q9VHA8-1", "name": "", "aln": "MALPLSDLLMIGGGEKKLAACLVLLLLELFLEGAESTASPADIENHLELGKEFLARGQLSDALTHYHAAVEGDANNYLTLFKRGTVYLALGKTRFAVQDFSRVLELKPDFMAARIQRGVVHMKSGEYEQAIQDFDQVLQEEPNNGLVLEHYSRLAPAQEQWVLVQQLIQYS---DHQNAIPMITQLLEISPWAVPFRQARSDAYIAINDPLLAIADLRQVNRLTQDSTEGHYKIAQLLYTIGHATNALKEIRECLKFDPEHKLCFPFYKKLRKVEKQLVNAEQAREEKHFAECIAAGEAVLRNEPEETMIRYEGHKVLCTCYTGDEQFGKALQQCKEALDIMKD-AQVYCDRADALLGTEMYDDAIHSFQAALDLEESNTRAKEGIQRAKKLQKQSERRDYYKILGVKRSASKQEIVKAYRKAAQKWHPDNFRDE-EKKVAEKKFIDIAAAKEVLTDPEKRRQFDNGEDPLDPESNQRGG---FHGEHP----FGHFQHGSPFQFKFHFN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . :: ::::* :*. . .::*:***:*:::** ***::**:::*:**:**..**:: ::*.**:**:**:: *: *:::.: ** ** ***:*** : :*.*. ::* :**. **: .* * .:* ::: * .: : * *: .: :::*:. * *: *::.:* .:* ** ** ..:* *. .. *:: * * :*. :*.::*****:* :.* **. **:::*:.* : .**: : :: :. *:*::.**. : ..:: * * :. :*: *.*. : : : ***:* : : *:.*:..:: * : ::.: . :**:::*::* * *.:*********.*.*.****:***** * :******:.* :** *********:*****:*** *::**.******.*.:* ** . *. *. *. *:***:**", "identical_positions": 176, "similar_positions": 174, "identity": "34.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000831-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9P1W9-1", "uniprot_id": "PIM2_HUMAN", "id": "Q9P1W9-1", "name": "Serine/threonine-protein kinase pim-2", "aln": "-----------------------------------------------------------MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAIKVIPRNRVLGWSPLSDSVT-CPLEVALLWKVGAGGG----HPGVIRLLDWFETQ-EGFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQTPAEDVPLNPSKGGPAPLAWSLLP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62070-1", "uniprot_id": "PIM2_MOUSE", "id": "Q62070-1", "name": "Serine/threonine-protein kinase pim-2", "aln": "MARATNLNAAPSAGASGPPDSLPSTLAPPSPGSPAALPRASTPCGLSGFSGLNIRSTSSMLTKPLQGHPSPPVTPTQPPGGKDRAAFEAEYRLGPLLGKGGFGTVFAGHRVTDRRQVAIKVISRNRVLGWSTVSDSVT-CPLEVALLWKVGEGNG----HPGVIRLLDWFETP-EGFMLVLERPMPAQDLFDYITEKGPLGESCSRSFFTQVVAAVQHCHARGVVHRDIKDENILIDLCRGSIKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGVLLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPCSRPSLEEILLDPWMQSPAEEKPINSSKGSPTPLPWSLLP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9YHZ5-1", "uniprot_id": "PIM2_DANRE", "id": "Q9YHZ5-1", "name": "Serine/threonine-protein kinase pim-2", "aln": "-----------------------------------------------------------MLDKRIVDVRLDQLEILKAKNGK--EHFEKQYTMGNLLGSGGFGSVYSGHRISDGQKVAIKQISRDRIQQWSKMPGEVNPVPNEIALLQSLGGGSGSVPGHRGIIRMLDWFEIPGQEYLIVFEKPQHCQDLFDFITERGALDESLARRFLKQVIEAVQFCHSKGIVHRDIKDENILVDTRTGDIKVIDFGSGATLKDSMYTDFEGTRVYSPPEWILYHKYHALPLTVWSLGVLLYDMVCGDIPFEQDTDIVKAKPSFNKRISNDCRSLICSCLSYNPGDRPSLEQILQHPWMMESSVD---NGDLQEESKIKPSL--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** * : . . .** ** :* :* ***.****:*::***::* :**** *.*:*: ** :...*. * *:*** .:* *.* * *:**:***** : :::*:*:* .*****:***:*.*.*. :* *: **: *:*.**::*:***********:* * *:******* *:*. ****:*********** *:***** ******:*************:* :*::*: * ::* ** :** **: :* .*****:** .*** .: : * . : : ** ", "identical_positions": 159, "similar_positions": 73, "identity": "42.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000906-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AWM3-1", "uniprot_id": "A0A8I6AWM3_RAT", "id": "A0A8I6AWM3-1", "name": "Spectrin beta chain", "aln": "----------------------------------------MTSATEFENVGNQ--------------PPYSRINARWDAPDDE------------------------------LDNDSSS------------------------ARLFERS-------------------RIKALADEREVVQKKTFTKWVNSHLARVSCRISDLYKDLRDGRMLIKLLEVLSGEMLPRPTKGKMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQT----QEGR-ETRSAKDALLLWCQMKTAGYPQVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLEHAFDVAERQLGIIPLLDPEDVFTENPDEKSIITYVVAFYHYFSKMKVLAVEGKRVGKVIDHAIETEKMIEKYSGLASDLLTWIEQTISVLNSRKFANSLSGVQQQLQAFSTYRTVEKPPKFQEKGNLEVLLFTIQSRMRANNQKVYTPHDGKLVSDINRAWESLEEAEYQRELALRSELIRQEKLEQLARRFDRKAAMRETWLNENQRLVTQDNFGYDLAAVEAAKKKHEAIETDTAAYEERVKALEDLAQELEKENYHDQKRISARKNNILRLWSYLQELLRSRRQRLEATLALQKLFQDMLHSIDWMDEIKAHILSAEFGKHLLEVEDLLQKHKLMEADIAIQGDKVKTITAATLQFTEGK--GYQPCDPQVIQDRVSHLEQCFSELSNMAAGRKAQLEQSKRLWKFFWEMDEAESWIKEKEQIYSSLDYGKDLTSVLILQRKHKAFEDELRGLDAHLKQIFQEAEDMVAQKQFGHPQIETRVKEVSAQWDHLKELAAFRKKDLQDAENFFQFQGDADDLKAWLQDAHRLLSGEDVGQDEGATRALGKKHKEFLEELEESRGVMEHLENQAQGFPEEFRDSPDVTNRLQALRKLYQQVMAQAELRGHKLQEALDLYTVFGESDACELWMTEKGKWLDQMDIPNTLEDLEVVQHRFDILDQEMKTLMAQIDGVNLAANNLVESGHPRSGEVKQYQDRLNKRWQAFQAVVSEQREAVDSALRVNNYCVDCEETSKWIVDKTKVVESTKDLGQDLAGVIAIQRKLSGLERDVLAIRDRVSALERESQYLMESHPDQKEDIGQRQADVEKMWKGLQDALQGQELSLGEASKLQAFLQDLDDFKAWLSMAQKAVASEDMPESLPEAEQLLQQHAAIKEEIDAHKDDYHRVKASGEKVIE--GQT-DPDYQLLGQRLEGLDTDWDALWRMWESRGNTLTQCLGFQEFQKDAKQAEAILSNQEYTLAHLEPPDSLAAAEAGIRKFEDFLVSMENNRDKVLSPVDSGNMLVSEGNLYSNKIKEKVQLIEDRHMKNNEKAQEVTALLKDNLELQNFLQNCKELTLWINDKLLTSPDISYDEARNLHNKWMKHQAFMAELASHQGWLENIVAEGRQLMAEKPQFTDVVSERLEALHKLWDELQTTTKAKTEQLSAARSSDLRLQTHADLSKWISAMEDQLR--SDDLGKDLTTVNRMLVKLKRVEEQVNLRKEELEELFAEAPPLGAEAGD---TDMSIEKR-----FLDLLEPLGRRKKQLELSKAKLQISRDLEDETLWVEERLPLAQSADYGTNLQTVQLFMKKNQTLQNEILGHAPRVEDVLHRGQELVKAAEIDCQD--IEERLGHLQSSWDTLREAAAGRLQRLREAHEAQQYYLDAGEAEAWISEQELYVFSDEPPKDEEGAIVMLKRHLRQQRTVEEYGRNIKQLAGRAQSLLSAGHPEGEQIIRLQGQVDKQYAGLKDMAEERRRKLENMYHLFQLKREADDLEQWITEKEMVASSQEMGQDFDHVTMLRDKFRDFARETGAIGQERVDNVNSIIERLIDAGHSEAATIAEWKDGLNDMWADLLELIDTRMQLLAASYDLHRYFYTGTEILGLIDEKHRELPEDVGLDASTAESFHRVHTAFERELHLLGVQVQQFQDVATRLQTAYAGEKADAIQSKEQEVSAAWQALLDACAGRRAQLVDTADKFRFFSMVRDLLSWMESIIRQIETQERPRDVSSVELLLKYHQGIKAEINTRAKNFSTCLELGESLLQRQHQASDEIREKLQQVISRRQEMNDKWEARSDRLHMLLEVCQFSRDASVAEAWLIAQEPYLASRDFGHTVDSVEKLIKRHEAFEKSTASWAERFAALEKPTTLELKERQTPD------RPTEEPGPQEEEGETAGEAPQVHHAATERTSPGEERGPWPQDLQPPPLPGHHKDEQEKSVGDERPATEPLFKVLDTPLS---------EGDEPTTLPAQRDLGHTVQMEGYLGRKHDLEGPNKKASNRSWNNLYCVLRNSQLTFYKDAKNLALG--VPYHGEEPLALRHAICEIAVNYKKKKHVFKLRLSNGSEWLFHGKDEEEMLLWLQGMSTAINESQSI------RVKAQSLPLPSLAGPDASVGKKDKEKRFSFFPKKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15508-1", "uniprot_id": "SPTB1_MOUSE", "id": "P15508-1", "name": "Spectrin beta chain, erythrocytic", "aln": "----------------------------------------MTSATEFENVGNQ--------------PPFSRINARWDAPDDE------------------------------LDNDNSS------------------------ARLFERS-------------------RIKALADEREVVQKKTFTKWVNSHLARVSCRISDLYKDLRDGRMLIKLLEVLSGEMLPRPTKGKMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQT----QEGR-EQRSAKDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLEHAFDVAERQLGIIPLLDPEDVFTENPDEKSIITYVVAFYHYFSKMKVLAVEGKRVGKVIDHAIETEKMIEKYSGLASDLLTWIEQTISVLNSRKFANSLSGVQQQLQAFSTYRTVEKPPKFQEKGNLEVLLFTIQSRMRANNQKVYTPHDGKLVSDINRAWESLEEAEYQRELALRSELIRQE--------FDRKAAMRETWLNENQRLVTQDNFGYDLAAVEAAKKKHEAIETDTAAYEERVKALEDLAQELEKENYHDQKRIIARKDNILRLWSYLQELLRSRRQRLEATLALQKLFQDMLHSIDWMDEIKAHILSAEFGKHLLEVEDLLQKHKLMEADIAIQGDKVKAITAATLQFAEGK--GYQPCDPQVIQDRVSHLEQCFSELSNMAAGRKAQLEQSKRLWKFFWEMDEAESWIKEKEQIYSSLDYGKDLTSVLILQRKHKAFEDELRGLDAHLKQIFQEADDMVAQKQFGHPQIETRVKEVSAQWDHLKELAAFRKKDLQDAENFFQFQGDADDLKAWLQDAHRLLSGEDVGQDEGATRALGKKHKEFLEELEESRGVMEHLEHQAQGFPEEFRDSPDVTNRLQALRKLYQQVLTQAELRGHKLQEALDLYTVFGESDACELWMTEKGKWLDQMDIPNTLEDLEVVQHRFDILDQEMKTLMAQIDGVNLAANNLVESGHPRSGEVKQYQDRLNKRWQAFQAVVSEQREAVDSALRVNNYCVDCEETSKWIMDKTKVVESTKDLGQDLAGVIAIQRKLSGLERDVLAIRDRVSALERESQYLMESHPEQKEDIGQRQADVEKLWKGLQDALQGQELSLGEASKLQAFLQDLDDFKAWLSMAQKAVASEDMPESLPEAEQLLQQHAAIKEEIDAHRDDYHRVKASGEKVIE--GQT-DPDYQLLGQRLEGLDTDWDALRRMWESRGNTLTQCLGFQEFQKDAKQAEAILSNQEYTLAHLEPPDSLAAAEAGIRKFEDFLVSMENNRDKILSPVDSGNKLVAEGNLYSNKIMEKVQLIEDRHKKNNEKAQEATVLLKDNLELQNFLQNCKELTLWINDKLLTSPDVSYDEARNLHNKWMKHQAFMAELASHQGWLENIDAEGRQLMAEKPQFKDVVSERLEALHKLWEELQSTAKAKAEQLSAARSSDLRLQTHADLNKWIGAMEDQLR--SDDLGKDLTTVNRMLAKLKRVEEQVNLRKEELEELFADAPSLGAEAGD---TDMSIEKR-----FLDLLEPLGRRKKQLELSKAKLQISRDLEDETLWVEERLPLAQSADYGTNLQTVQLFMKKNQTLQNEILGHAPRVEDVLRRGQELVKAAEIDCQD--IEERLGHLQSSWDTLREAAAGRLQRLRDAHEAQQYYLDAGEAEAWISEQELYVFSDEPPKDEEGAIVMLKRHLRQQRTVEEYGRNIKQLAGRAQSLLSAGHPEGEQIIRLQGQVDKQYAGLKDMAEERRRRLENMYHLFQLKREADDLEQWITEKEMVASSQEMGQDFDHVTMLRDKFRDFARETGAIGQERVDNVT-IIERLIDAGHSEAATIAEWKDGLNDMWADLLELIDTRMQLLAASYDLHRYFYTGTEILGLIDEKHRELPEDVGLDASTAESFHRVHTAFERELHLLGVQVQQFQDVATRLQTAYAGEKADAIQSKEQEVSAAWQALLDACAGRRAQLVDTADKFRFFSMVRDLLSWMESIIRQIETQERPRDVSSVELLLKYHQGIKAEINTRAKNFSTCLELGESLLQRQHQASDEIREKLQQVISRRQEMNDKWEARSDRLHMLLEVCQFSRDASVAEAWLIAQEPYLASRDFGHTVDSVEKLIKRHEAFEKSTASWAERFAALEKPTTLELKERQTPE------RPTEEPGPQEEEGETAGEAPQVHHAATERTSP-------------------------------VSFMSRLSSSWESLLP---------EPAHPF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11277-1", "uniprot_id": "SPTB1_HUMAN", "id": "P11277-1", "name": "Spectrin beta chain, erythrocytic", "aln": "----------------------------------------MTSATEFENVGNQ--------------PPYSRINARWDAPDDE------------------------------LDNDNSS------------------------ARLFERS-------------------RIKALADEREVVQKKTFTKWVNSHLARVSCRITDLYKDLRDGRMLIKLLEVLSGEMLPKPTKGKMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQT----QEGR-ETRSAKDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLEHAFNVAERQLGIIPLLDPEDVFTENPDEKSIITYVVAFYHYFSKMKVLAVEGKRVGKVIDHAIETEKMIEKYSGLASDLLTWIEQTITVLNSRKFANSLTGVQQQLQAFSTYRTVEKPPKFQEKGNLEVLLFTIQSRMRANNQKVYTPHDGKLVSDINRAWESLEEAEYRRELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVAQDNFGYDLAAVEAAKKKHEAIETDTAAYEERVRALEDLAQELEKENYHDQKRITARKDNILRLWSYLQELLQSRRQRLETTLALQKLFQDMLHSIDWMDEIKAHLLSAEFGKHLLEVEDLLQKHKLMEADIAIQGDKVKAITAATLKFTEGK--GYQPCDPQVIQDRISHLEQCFEELSNMAAGRKAQLEQSKRLWKFFWEMDEAESWIKEKEQIYSSLDYGKDLTSVLILQRKHKAFEDELRGLDAHLEQIFQEAHGMVARKQFGHPQIEARIKEVSAQWDQLKDLAAFCKKNLQDAENFFQFQGDADDLKAWLQDAHRLLSGEDVGQDEGATRALGKKHKDFLEELEESRGVMEHLEQQAQGFPEEFRDSPDVTHRLQALRELYQQVVAQADLRQQRLQEALDLYTVFGETDACELWMGEKEKWLAEMEMPDTLEDLEVVQHRFDILDQEMKTLMTQIDGVNLAANSLVESGHPRSREVKQYQDHLNTRWQAFQTLVSERREAVDSALRVHNYCVDCEETSKWITDKTKVVESTKDLGRDLAGIIAIQRKLSGLERDVAAIQARVDALERESQQLMDSHPEQKEDIGQRQKHLEELWQGLQQSLQGQEDLLGEVSQLQAFLQDLDDFQAWLSITQKAVASEDMPESLPEAEQLLQQHAGIKDEIDGHQDSYQRVKESGEKVIQ--GQT-DPEYLLLGQRLEGLDTGWNALGRMWESRSHTLAQCLGFQEFQKDAKQAEAILSNQEYTLAHLEPPDSLEAAEAGIRKFEDFLGSMENNRDKVLSPVDSGNKLVAEGNLYSDKIKEKVQLIEDRHRKNNEKAQEASVLLRDNLELQNFLQNCQELTLWINDKLLTSQDVSYDEARNLHNKWLKHQAFVAELASHEGWLENIDAEGKQLMDEKPQFTALVSQKLEALHRLWDELQATTKEKTQHLSAARSSDLRLQTHADLNKWISAMEDQLR--SDDPGKDLTSVNRMLAKLKRVEDQVNVRKEELGELFAQVPSMGEEGGD---ADLSIEKR-----FLDLLEPLGRRKKQLESSRAKLQISRDLEDETLWVEERLPLAQSADYGTNLQTVQLFMKKNQTLQNEILGHTPRVEDVLQRGQQLVEAAEIDCQD--LEERLGHLQSSWDRLREAAAGRLQRLRDANEAQQYYLDADEAEAWIGEQELYVISDEIPKDEEGAIVMLKRHLRQQRAVEDYGRNIKQLASRAQGLLSAGHPEGEQIIRLQGQVDKHYAGLKDVAEERKRKLENMYHLFQLKRETDDLEQWISEKELVASSPEMGQDFDHVTLLRDKFRDFARETGAIGQERVDNVNAFIERLIDAGHSEAATIAEWKDGLNEMWADLLELIDTRMQLLAASYDLHRYFYTGAEILGLIDEKHRELPEDVGLDASTAESFHRVHTAFERELHLLGVQVQQFQDVATRLQTAYAGEKAEAIQNKEQEVSAAWQALLDACAGRRTQLVDTADKFRFFSMARDLLSWMESIIRQIETQERPRDVSSVELLMKYHQGINAEIETRSKNFSACLELGESLLQRQHQASEEIREKLQQVMSRRKEMNEKWEARWERLRMLLEVCQFSRDASVAEAWLIAQEPYLASGDFGHTVDSVEKLIKRHEAFEKSTASWAERFAALEKPTTLELKERQIAE------RPAEETGPQEEEGETAGEAPVSHHAATERTSP-------------------------------VSLWSRLSSSWESLQP---------EPSHPY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B5B6-1", "uniprot_id": "A0A8M2B5B6_DANRE", "id": "A0A8M2B5B6-1", "name": "Spectrin beta chain", "aln": "MSSPCLCRAVPVSQTRLREVKLSLKTSRETIAIRSTPVVREVSSRQYTTVKDVPTRTNAPGSRSRSTPPVYRAQSKRGAKNNSPHIGEPEHLPERNGTLLGITPKLAPMTLTSISSTSSSSSSCTPRGHRPSPLRSSPSCPLSPSRGMRRARWLSYSASNICFNNSILDGRFRQLQDEREAVQKKTFTKWVNSILARVSCRISDLYLDLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLILGLIWTIILRFQIQDIIVETGQADQTGRQETRSAKDALLLWCQMKTAGYPNINITNFTTSWKDGMAFNALIHKHRPDLVDYGNLKRSNPTHNLQQAFNVAEKKLGVTKLLDPEDVFTENPDEKSIITYVVAFYHYFSKMKALAVEGKRIGKVLDQAIETEKMIEKYETLSSDLLTWIEQTIVVLNNRKLANSLTGVQQQLQAFNSYRTVEKPPKFQEKGNLEVLLFTIQSRMRANNQKVYTPKEGALVSDINKAWERLEKAEYDRERVLRDELIRQEKLEQMARRFDRKAAMRETWLMENQRLVSQDNFGYDLPAVEAAKKKHDAIETDIAAYEERVQALVALSKELESERYHDAKRIDARKDNILRLWDYLQELLKARRGRLDKNLTLQRIFQEMLHIISWMDEMKGRLLSPDFGKHLLEVEDLLQKHSLVEADIAVQAERVKSANAAALKFANGD--SYKPCDPQVIRDRVQHLDLCYQELCALAAQRKARLEQSRRLWNFLWEIAELESWIREREQIFSSLDYGKDLTSVLILQSKHSVFEDELAARRDNLKQVMDEGESMIQIKHLGSPKVQQRMNDVQRQWQQLEELAAFRKQNLQDTQRFFQFQGDADDLKAWLVDAMRQMSSDDVGHDEYTTQRLLKKHRDLRDEAAKNGATIDALSKQANALPEELRNTPDIQGRLNDIRDMYIELLTLSDLRQKKLDDTMALYTIFSETDACELWMGQKETWLVGLETPENLEDLEIVQNRLSILAQEMGNMQTRVDNVNKAAKQLEDSRHPQTKQVKDCQIRLNKRWEAFKAMVEDKKHRVDSALSLHNYDLDCDETESWIKEKTRVIESTQDLGNDLAAVITIQRKLFGMERDLAAIQDKLDSLRDEAQKLVKEHPENASDILARQEELDAAWDTLKRTLKDREDSLGEVSKLQTFLQDMDDFQAWLFKSQKAVASEDMPDGLPEAEQLLNLHDALRHDMDGHEEDYHRVKDTGAAVIQ--GQEDDPQYQQLEQRLEGLDKGWGELHKMWDSRKNFLDQGLGFQQFMRDAKQADAILNNQEYTLAHVDKPDTLDGAEKALKKHEDFVTTMDANKEKILSTLETGQRLVDSENLYSGKVKDKMSSIEERNKKNQDKAKEVSGKLKDNRELQHFLQNTQDLTLWINEKMLTAQDTSYDEARNLHSKWQKHQAFMAELASNKDWLHNIDKEGQELMESKPEFEPIVKDRLAKLHELWDKLESTTQEKARLLFDANRSELFDQSLADLKKWLAELQQQLQGDVEEEVKDLTSANILLKKHQITENQVRDRARELEELQEAVEQHGSLREDQ--PELEIEQQNLQRDFQKLLTPLSQRKGKLEAAKAVHQFFRDLADEILWVNERLPMAMSDDHGNNLQTVQLLLKKNQSLQKEIDGHQPRIDEVLERGRRMAAAAEGSPEEERMSEEMKKLQVVWAQLQEEMAKRRERLYGSNEAQQYYNDADDSEAWIGEQELYMIADEMAKDEQSAMIMLKRHLVLKQTVDDYAYSIQQLADRAQKMLAEEHPDGEAIIRRQGQVDKQYAGLKELAEDRKKKLDHTYHHFLLSREVEDLEQWIAERDVVASSQEMGQDLDHVTILRDKFREFARETGTVGQERVDTVNRIIDELIEGGHSESATLAEWKDGVNESWADLLELIDTRAQLLTSSYDLLKYFYDGKELVGHIEEKKNELPEDLGEDFSKAESFHRMHAAFERDISSLGKQVKQFQETAARLHAQYAGDQATAIQATEKEVVEAWKGLLDACAGRRKQLEETADKFRFFTMVRDLMAWMESILQQIETQEKPRDVSSVELLMKYHQGIRAEIETRGPKFNQCVQLGQALLERKHKDSAEIKEKLMQLVEKRKEMMLKWDDRWDWLRLLLEVCQFARDASVAEAWLIAQEPYVASKDVGQTVDEVEKLLKRHEAFEKSTATWEERFSALERLTTLELLEIRKQQQEIQQYRQEAEKESRREDTGFAEESSQLYPTEEQSLSGLGVIEPSSGGVDG------------TAGESTVPLISEMQESVSLELDPSTSIQVTKETEKAASLPTESTQVQPVLMEGTLARKHELEGPNKKAPNRSWNNLYCVLKPGHLSIYKDAKSFSHS--VTFHGEEPLTLTNSSCEILTNYKKKKQVFKLRLGDGSEYLFQCKDEEELQNWTQAIEQAAQVQIEEPVAGPSGVKALSLPPPSSTTLEVPSTKKDKEKRFSLFAKKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q00963-1", "uniprot_id": "SPTCB_DROME", "id": "Q00963-1", "name": "Spectrin beta chain", "aln": "------------------------------------------MTTDISIVRWD--------------PSQGPGNEYIDEYEYD--------------------------------GGNSS------------------------SRLFERS-------------------RIKALAEERESVQKKTFTKWVNSHLCRVNCRIADLYVDMRDGKHLIKLLEVLSGERLPKPTKGKMRIHCLENVDKALQFLREQRVHLENIGSHDIVDGNASLNLGLIWTIILRFQIQDITIEE----VDNK-ETKSAKDALLLWCQMKTAGYHNVNVRNFTTSWRDGLAFNAIIHKHRPDLVQFEKLSKTNAIHNLNNAFDVAEDKLGLAKLLDAEDVFVEHPDEKSIITYVVTYYHYFSKLKQETVQGKRIGKVVGIAMENDKMVHDYENFTSDLLKWIETTIQSLGEREFENSLAGVQGQLAQFSNYRTIEKPPKFVEKGNLEVLLFTLQSKMRANNQKPYTPKEGKMISDINKAWERLEKAEHERELALREELIRQEKLEQLAARFDRKASMRETWLSENQRLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESERYHDVKRILLRKDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLMTDDYGKHLMGVEDLLQKHSLVEADINILGERVKVVVQNSQKFLSDDPESYKPCDPEIIVSRVQQLEDAYAELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTTVNLMLSKHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDLTKYRRQRLENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVADELKNYAEVIDALHKQAESLKLNEAEKANVDKRLEAIDNRYKELTELAKLRKQRLLDALSLYKLMSEADGVEQWIKEKTKMLDTMTPGKDIEDVEIMKHRFEGFDKEMNANASRVAVVNQLARQLLHVEHPNSDEILERQNHLNQEWSTLREKAEAKMDDLKSAHGVQTFYIECRETISWIEDKKRILTETDSLEMDLTGVMTLQRRLSGMDRDLAAIQAKLSSLEREANSIEDEHPEEAKIIRERIAQIELIWEQLTQMLKERDSKLEEAGDLHRFLRDLDHFQTWLTKTQTDVASEDTPTSLPEAEKLLNQHQSIREEIDNYTEDYKNMMEYGERLTSEGSTSDDPQYMFLRERLNALKDGWEELHQMWENRQVLLSQSLDQQLFNRDARQTEVLLSQQEHFLSKDDTPVNLEQAENQLKRHEAFLTTMEANDDKINTLLQVADTLVEKDHFDADKIGKRAENITGRRDDNRQRALDQHEKLKNQVKLHEFLQDLEELAEWVQEKYATSQDESYRSAKTIHSKWTRHQAFEAEIAANKERLFEAEKSAQELSKEKPEFKDVIEPKLKELAKQFDDLEVHTKEKGAMLFDANREVLVQQTCDDIDSYITDLEKQIV--SGDTANDLTSVNILMQKQQVIQTQMAVKARQVEEIDKQTEYLQKTVPEEKIEPIVVKKTAVLERFEKIKAPLLERQKALEKKKEAFQFCRDVEDEKLWIDEKLPVANSPDYGNSLFNVHVLKKKNQSLATEIDNHEPRINAICNNGRKLIDEGHEDAKK--FEALISDLTQKWQELKDAIENRRKHLLESEKVQQYFFDAQEAESWMSEQELYMMVEDRGKDEISAQNLMKKHENLEQSVEDYANTIRQLGEVARQFSGDDISSGDAVAVKQSQLDKLYAGLKDLAGERRARLNEALQLFMLSREVDDLEQWITDREVVAGSQELGQDFDHVTLLSERFNEFARDTEAVGGERVAKVNGIADNLIQAGHSDSATIAEWKDNLNESWQDLLELIETRTQMLAASRELHKFFHDCKDVLGRILEKQHGVSDELGRDAGSVSTLQRKHYNFLQDLITLYSQVQQIQEESAKLQDAYAGDKAKEITNREQEVLHAWDNLQAMCDARKQKLADTGDLFRFFNMVRILMIWMEDLVRQMNTSEKPRDVSGVELLMNNHQSLKAEIDTREDNFGACISLGKELLTRNHYASADIKDRLMTLSNSRNALLRRWEERWENLQLILEVYQFARDAAVAEAWLIAQEPYLLSSELGHTIDEVENLIKKHEAFEKSAAAQEERFSALERLTTFELKEMKRRQE--LAEEAERQRIKEEQEAKAASEAAEQAKREAERRDD-------------------------------VDVGASHDDSERGGTP---------GAGEGH--------------EGYVTRKHEWDSTTKKASNRSWDKVYMAAKAGRISFYKDQKGYKSNPELTFRGEPSYDLQNAAIEIASDYTKKKHVLRVKLANGALFLLQAHDDTEMSQWVTSLKAQSD--------------STAVAASRSQTLPATSQKDEPKRRSFFTLKKK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * *. : . : . . .** :* :.*: *:: * :*** ************ *.**.***:*** *:***: *********** **:****:****************:**:*****:********* * **************** :: .: * :***************** ::*: ***:**:**:****:********::: :*. :*. ***::**:*** :**: ***.****.*:***********::******:* :*:***:***:. *:*.:**:..*. ::****.*** ** *..*:: ***:*** ** *..***:****** ***********:**:******* ***::* ::****:*** **:**: ** .**.****** *****:****** ******:*****:**.***** ***:***** ******:*: :..***.*.*** *** **:*::*** ** ***::** **: .* **: **:**: :. *:*:* ::: ::****: ********.*:**** : .::** : :* ... .*:****::* .*:.:*: .: ** :*. *:::**:*::**:* *: : *.**:*:*** *: : *:***:* :: **..:*.*: . :*::: . . :: ::* ::: *:::: :*::* :*: : :: *::: .:**: .****:. *: *: * :*.:***:** .: * ***::. :* : .:: * :**:.: : :..:: **: : . * :: :.** ::* ::: **.::.*:*. * *: :* . * : . :**:*::::*:. : :** ::: ** *..* . **.: :: : * :** .*.::: .. : . :.** ::.: ::* ** .** :*.::: .*..* **:.::::**:* *::**: **: ::.:*. *:: : ..**:: . * * .:: *. * *: :: * *...*: **:*:*.*::** :*. ***** * .*****:**: * .::.::* : :.*:.: * : . . **:* * :**:.*. .* * :**:.* * * *. * * :**:*::.:*.:**: *:: : * .* ** :::.* *: :*: * :*: : :: .: ** . :: :.*: .: . * *. .*.::* : *::: :*:.***: ::*: *:::* *: * ** .*:.:*.** :**** **:*::: * : ..::* .**:* ::. :* * . ::.*: :: * * *. . * *: *:..:: ::.*: : :***:.* :: * : : *: : .:: *: . : : ::: * .: ** .*: ** : *: **: ** **::*:**:* * *:*..* .*::: ****:* .** .* **:: : ..*:.: .. . :. :. : .* * *:: * ::* :.:.***: ** ::*:*:.*****:: :: *** .* ::*:* :::*::*. .*:**. *: : . ..*: : *.*:** *****::* :*: :*:. : * *.**.:******:::::**.* *:***:****:* ::*.:***:* ::* *** .*. : :.**:.***::**:*****.:*: * ******:** *:*::* :* ::*: :::* * **:. :.:::* * ....:::* * * ::: * **:*:*: :::*: ***::* * *:** **. * * .*: :* :*.* ****.*.* *: ***.:::*::*.*:*****.****:: **.:.***:** :*. *:.**: ** *:* * :*:::* : . *: : :*: * : *:::*** **:***:************: * :.*:*:*.**:*:*:*******:*: ***:***: **:** * : : . : ..:: * *:. : . . . ", "identical_positions": 859, "similar_positions": 717, "identity": "34.35%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000921-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q504M2-1", "uniprot_id": "PDP2_MOUSE", "id": "Q504M2-1", "name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial", "aln": "MSSTVSYWIFNSARNRIALLRGGRRLYSRAATSRNLLKWRPFSPALASSALKCGSPPGG----FALRKAYRHTSTEEEDFHLQLSPEQVSDLLRAGESSHKVLDFNN-GVPNSVLRFESNQLAANSPVEDRQGVATCVQTNGMMFGIFDGHGGHACAQAVSERLFYYMAVSLMSHQTLEQMEEATENMKPLLPILRWLKHP-----GDSIYKDVTSVHLDHLRVYWQELLD-LHMEMGLSIEEALMYSFQRLDSDISLEIQAPLEDEVTRN--LSLQVAFSGATACMAHVNGVH--LHVANAGDCRAILGVQE-ENGAWSCLPLTCDHNAWNEAELSRLKREHPESEDRTLIIDDRLLGVLMPCRAFGDVQLKWSKELQRNVLARG-FDTEALNIYQFTPPHYYTPPYLTAKPEVTYHRLRRQDKFLVLASDGLWDMLGNEDVVRLVVGHLSKVGRHKPD-LDQRPAN--LGLMQSLLLQRKASGL---------------HAADQNTATHLIRHAIGSNEYGEMEPERLAAMLTLPEDVARMYRDDITVMVVFFNSDSIDTYCKEG-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88484-1", "uniprot_id": "PDP2_RAT", "id": "O88484-1", "name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial", "aln": "MSSTASYRIFNFARNRIAVLRGGRRLYSRAATSRNQVKWRLFSP--ASLAVNDSSPHGG----FALRKAYRHTSTEEEDFHLQLSPEQVSDLLRAGESSHKVLDFNS-GVPNSVLRFESNQLAANSPVEDRQGVASCVQTRGTMFGIFDGHGGHACAQAVSERLFYYMAVSLMSHKTLEQMEEAMENMKPLLPILQWLKHP-----GDSIYKDITSVHLDHLRVYWQELLD-LHMETGLSTEEALMYSFQRLDSDISLEIQAPLEDEVTKN--LSLQVAFSGATACMAHVDGVH--LHIANAGDCRAILGVQG-DNGAWSCLPLTCDHNAWNEAELSRLKREHPESEDRTLIIDDRLLGVLLPCRAFGDVQLKWSKELQRNVLERG-FDTEALNIYQFTPPHYHTPPYLTAKPEVTYHRLRPQDKFLVLASDGLWDMLDNEDVVRLVVGHLSKVGHQKPA-LDQRPAN--LGHMQSLLLQRKASGL---------------HAADQNAATHLIRHAIGSNEYGEMEPERLAAMLTLPEDVARMYRDDITVMVVFFNSESIDTYFKEG-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P2J9-1", "uniprot_id": "PDP2_HUMAN", "id": "Q9P2J9-1", "name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial", "aln": "MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSR--VPPTLN-SSPCGG----FTLCKAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLES-RVPNSVLRFESNQLAANSPVEDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESMKPLLPILHWLKHP-----GDSIYKDVTSVHLDHLRVYWQELLD-LHMEMGLSIEEALMYSFQRLDSDISLEIQAPLEDEVTRN--LSLQVAFSGATACMAHVDGIH--LHVANAGDCRAILGVQE-DNGMWSCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERG-FNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSNEDVVRLVVGHLAEADWHKTD-LAQRPAN--LGLMQSLLLQRKASGL---------------HEADQNAATRLIRHAIGNNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P8M8-1", "uniprot_id": "A0A8M1P8M8_DANRE", "id": "A0A8M1P8M8-1", "name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial", "aln": "MSGYLRSALLLGTR--------GRHLSSSFAASQHVLPDVACRALLFSSPARSFSSRGGRSDGSSGQEGENRLHPPRHEMDFQMSRLQINAVLRANEQSVRVPEFDGRGGPSPVLRFESNQLPANTPLEDRRSSASSLQTRSMLFGVFDGHGGHACAQAVSERLPYYISVAMMAESVLEDLEAAMETSRPVPPILQWYKHH-----NDYNYRESAALYVDHLRVFWQELLASEEHGDGMRPADALSYAFQRLDTDLSLEAQVPLANDLMRN--TALQAAFAGCTACVAHVGPEG--VHVANAGDCRAVLGVQE-TDGSWSALPLTKDHNAANVAEMERVWRQHPASERQTVVVDDRLLGVLMPLRAFGDVRFKWSRELQQSVLENGDSDLEALNIYQYAPPNYLTPPYLEVTPEVTHHRLRPQDRFLILASDGLWDEMSNDEAVRLVAEHLTGVHLQAP--VSARQLN--LGQMHQLLLRRRARAT---------------PALDLNAATHLIRHALGTNEYGEMDQERLATMLALPSDLARMYRDDITVTVIYFNPNFNKNNNKEH-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3Q1-1", "uniprot_id": "Q9W3Q1_DROME", "id": "Q9W3Q1-1", "name": "", "aln": "MFKFVLNDAASYVR------------SNVREFSLNALRLLPQLP--------------------------------------QLSPYDVNLVLRENEFVYNFP------VDGVIRSYETNQLGSNWPCEDSRTEASFLHRNGFICGIFDGHAGAACGQVVSKRLLRYVSAATLPRQVLR------EQMKQGADSQSFLKCH-----NDN--VDFVSMIKPMYEASFLKYVNQLLETPQRDVSSELVNAFLQLDEEISQEALT--SNDVR-----TMNVALSGAVACLVHIEGLQ--MHVASTGDCGAVLGVLDPQTQQWHSKKLNIEHNADNMSEVRRILAEHPKEEHETVIRNGRLLSQLAPLRAFGDFRYKWSQEIMQ-------QKVLPMFGVQAMAPNYYTPPYLTARPDVQQHELGPNDKFLVIASDGLWDFLPPSEVVSLVGEHINSKKILEPMRLPEGDTT--LQEISQQLAERKAGLTR--------------KPVDQNAATHLIRHALGGTDYG-IEHSKISYYLTLPRDAVRLYRDDITITVIYFNSEHIAKLHSDVDQTEVTAPVA-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12511-1", "uniprot_id": "PDP1_YEAST", "id": "Q12511-1", "name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial", "aln": "MSPLTRTVAIKKTVKVLSKCQSGREYTQKFLQRAYSTSHANSTYYSRTKLFISSHSKALNIALLSGSLLLTYSYYSPKKILSLDTINGIKDYSTNTSGNINMPSPNPKGTETQKSQRSQNDQSVLILNDSKIEAKLHDREESHFVNRGTGIFRYDVAQLPSNHPIEDDHVEQIITIPIESEDG--KSIEKDLYFFGIFDGHGGPFTSEKLSKDLVRYVAYQLGQVYDQNKTVFHSDPNQLIDSAISKGFLKLDNDLVIESFRKLFQDPNNTNIANTLPAISGSCALLSLYNSTNSILKVAVTGDSRALICGLD-NEGNWTVKSLSTDQTGDNLDEVRRIRKEHPGEPN--VIRNGRILGSLQPSRAFGDYRYKIKEVDGKPLSDLP---EVAKLYFRREPRDFKTPPYVTAEPVITSAKIGENTKFMVMGSDGLFELLTNEEIASLVIRWMDKNMNLAPVKAEPGKLPKVIDVSEDKEAQRPAFRYKDNNSSSPSGSNPEYLIEDKNVATHLIRNALS----AGGRKEYVSALVSIPSPMSRRYRDDLTVTVAFFGDSGTPSIVSNATSIVMNPEATTKPKPRL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . : :. . .. . *: :. : .. : . * .* *:: . : :. : . . .: : . : : . : .* :** :: * :: *::*. * : :::* :**. *:: * *. ::.. * *: *: :** . :: :.*:*. * * ***** : * .. : . : . .: ****: . * : .: : :*:::.****:: : .: . ** : . : . .* * * *.**:***:*:. . . :: :::* * ****:*: * :*. . . ", "identical_positions": 64, "similar_positions": 116, "identity": "10.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000926-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LH80-1", "uniprot_id": "A0ABK0LH80_RAT", "id": "A0ABK0LH80-1", "name": "", "aln": "----------------------------MKSACKPHGPPAGARGAPPCAGAAERAVSCAGPGRLESAARRRLAANARERRRMQG-----LNTAFDR--------------------------------------------LRRVVPQWGQDKKLSKYETLQMALSYIVALTRILAEAER------DWVGLRCEQ-----------------------RGRNHPYLPFPGARLQVDPEPYGQKFFGFQPESFPMAS------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2E5-1", "uniprot_id": "ATOH7_MOUSE", "id": "Q9Z2E5-1", "name": "Transcription factor Atoh7", "aln": "----------------------------MKSACKPHGPPAGARGAPPCAGAAERAVSCAGPGRLESAARRRLAANARERRRMQG-----LNTAFDR--------------------------------------------LRRVVPQWGQDKKLSKYETLQMALSYIIALTRILAEAER------DWVGLRCEQ-----------------------RGRDHPYLPFPGARLQVDPEPYGQRLFGFQPEPFPMAS------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N100-1", "uniprot_id": "ATOH7_HUMAN", "id": "Q8N100-1", "name": "Transcription factor ATOH7", "aln": "----------------------------MKS-CKPSGPPAGARVAPPCAGGTECAGTCAGAGRLESAARRRLAANARERRRMQG-----LNTAFDR--------------------------------------------LRRVVPQWGQDKKLSKYETLQMALSYIMALTRILAEAERFGS-ERDWVGLHCEH-----------------------FGRDH-YLPFPGAKLPGESELYSQRLFGFQPEPFQMAT------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AW52-1", "uniprot_id": "ATOH7_DANRE", "id": "Q8AW52-1", "name": "Transcription factor atoh7", "aln": "--------------------------------MKPR--------RPSCADSGSDSDSRD-PEKFESAMRRRMAANARERKRMQG-----LNTAFDR--------------------------------------------LRKVVPQWGQDKKLSKYETLQMALSYIMALNRILSDAGRHVDPQKDWLNLQFDG-----------------------LQTEGYFMHYDSP---VESD-CMLSSFSYHYESL----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48987-1", "uniprot_id": "ATO_DROME", "id": "P48987-1", "name": "Protein atonal", "aln": "MSSSEIYRYYYKTSEDLQGFKTAAAEPYFNPMAAYNPGVTHYQFNGNTLASSSNYLSANGFISFEQASSDGWISSSPASHRSESPEYVDLNTMYNGGCNNMAQNQQYGMIMEQSVVSTAPAIPVASPPAVEVMGSSNVGTCKTIPASAGPKPKRSYTKKNQPSTTATSTPTAAAESSASVNLYTEEFQNFDFDNSALFDDSVEDDEDLMLFSGGEDFDGNDGSFDLADGENQDAAAGGSGKKRRGKQITPVVKRKRRLAANARERRRMQNLNQAFDRLRQYLPCLGNDRQLSKHETLQMAQTYISALGDLLR---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9Y0A7-1", "uniprot_id": "AMOS_DROME", "id": "Q9Y0A7-1", "name": "Basic helix-loop-helix transcription factor amos", "aln": "--------------------------------MLTNNELMEQFYFPDEAPAIPEFLSNDTFQQLEQLMYQQEFSTSDSQSDGAN--SCSLEMYYDT-------------------------------------------------PSVLELEHMLNAQEQQQHHLQANPLGKNQGRSPR------YWNK----------------------------QQRSKPYDKLSTSMSSSTSSASSSSSSSAGFGGEVLKKRRLAANARERRRMNSLNDAFDKLRDVVPSLGHDRRLSKYETLQMAQAYIGDLVTLLSRDY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :*. :.: . *: :: .. : : * . : : . : . . ", "identical_positions": 3, "similar_positions": 22, "identity": "0.95%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-000928-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GEM4-1", "uniprot_id": "A0A8I6GEM4_RAT", "id": "A0A8I6GEM4-1", "name": "Ferrochelatase", "aln": "MGPEPRLGEKIRVASKKIKPPLRMGLKPQPTGEGGLQRVSLPEEMLGKPPLPGVVYGSSRACQPWRCQSGP-AVVATTEKAHHAKTTKPQAQPERRKPKTGILMLNMGGPETLGEVQDFLQRLFLDRDLMTLP--IQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKMWTSKQGEGMVKLLDELSPDTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNEVGRKPTMKWSTIDRWPTHPLLIQCFADHILKELDHFPEEKRSEVVILFSAHSLPMSVVNRGDPYPQEVGATVHRVMEQLGYPNPYRLVWQSKVGPVPWLGPQTDEAIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAQKCGAENIRRAESLNGNPLFSKALADLVHSHIQSNKLCSTQLSLSCPLCV-NPVCRKTKSFFTSQQL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22315-1", "uniprot_id": "HEMH_MOUSE", "id": "P22315-1", "name": "Ferrochelatase, mitochondrial", "aln": "----------MLSASANMAAALRA--------AGALLREPL-------------VHGSSRACQPWRCQSGA-AVAATTEKVHHAKTTKPQAQPERRKPKTGILMLNMGGPETLGEVQDFLQRLFLDRDLMTLP--IQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKMWTSKQGEGMVKLLDELSPATAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNEVGQKPTMKWSTIDRWPTHPLLIQCFADHILKELNHFPEEKRSEVVILFSAHSLPMSVVNRGDPYPQEVGATVHKVMEKLGYPNPYRLVWQSKVGPVPWLGPQTDEAIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAQKCGAENIRRAESLNGNPLFSKALADLVHSHIQSNKLCSTQLSLNCPLCV-NPVCRKTKSFFTSQQL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22830-1", "uniprot_id": "HEMH_HUMAN", "id": "P22830-1", "name": "Ferrochelatase, mitochondrial", "aln": "----------MRSLGANMAAALRA--------AGVLLRDPL-------------ASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQVQPQKRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLP--IQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCV-NPVCRETKSFFTSQQL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PIE9-1", "uniprot_id": "A0A8M9PIE9_DANRE", "id": "A0A8M9PIE9-1", "name": "Ferrochelatase", "aln": "----------MAVLGG----------------ACRLVQLVR--------------CGS----PVGLCLSSSLRRQSTATAAAFNTTATPETK-ESRKPKTGILMLNMGGPEKLEDVHDFLLRLFMDTDLMQLP--VQNKLGPFIAKRRTPKIQEQYSKIGGGSPIKAWTTMQGEGMVKLLDEMCPDTAPHKFYIGFRYVHPLTEEAIELMEKDGVERAVAFTQYPQYSCSTTGSSLNAIYRYYSNRADRPKMRWSVIDRWPTHPLLIECFAEHVRNELDKFPVEKRDDVVILFSAHSLPLSVVNRGDPYPQEVGATVQRVMDRLGHCNPYRLVWQSKVGPMAWLGPQTDEVIKGLCQRGKRNLLLVPIAFTSDHIETLHELDIEYSQVLGEEVGVENIRRAESLNGNPLFFRALADLVQSHLQSNESCSRQLTLRCPLCV-NPTCAQTKAFFSSQKL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V9S8-1", "uniprot_id": "HEMH_DROME", "id": "Q9V9S8-1", "name": "Ferrochelatase, mitochondrial", "aln": "-----------------------------------------------------------------MFLHNTKFCRLASGLAGGVRNLS------GQKPKTAILMLNMGGPTHTDQVHDYLLRIMTDRDMIQLP--VQSRLGPWIAQRRTPEVQKKYKEIGGGSPILKWTELQGQLMCEQLDRISPETAPHKHYVGFRYVNPLTENTLAEIEKDKPERVVLFSQYPQYSCATSGSSFNSIFTHYRSNNLPSDIKWSIIDRWGTHPLLIKTFAQRIRDELAKFVETKRNDVVILFTAHSLPLKAVNRGDAYPSEIGASVHMVMQELGQTNPYSLAWQSKVGPLPWLAPATDDAIKGYVKQGLKNFILVPIAFVNEHIETLHELDIEYCDELAKEVGVEEIRRAATPNDHPLFIDALTNVVADHLKSQQAVNPKFLMRCPMCS-NPKCRESKSWYRQLCSN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P16622-1", "uniprot_id": "HEMH_YEAST", "id": "P16622-1", "name": "Ferrochelatase, mitochondrial", "aln": "-------------------------------------------------------------MLSRTIRTQGSFLRRSQLTITRSFSVTFNMQNAQKRSPTGIVLMNMGGPSKVEETYDFLYQLFADNDLIPISAKYQKTIAKYIAKFRTPKIEKQYREIGGGSPIRKWSEYQATEVCKILDKTCPETAPHKPYVAFRYAKPLTAETYKQMLKDGVKKAVAFSQYPHFSYSTTGSSINELWRQIKALDSERSISWSVIDRWPTNEGLIKAFSENITKKLQEFPQPVRDKVVLLFSAHSLPMDVVNTGDAYPAEVAATVYNIMQKLKFKNPYRLVWQSQVGPKPWLGAQTAEIAEFLGPK-VDGLMFIPIAFTSDHIETLHEIDLG---VIGESEYKDKFKRCESLNGNQTFIEGMADLVKSHLQSNQLYSNQLPLDFALGKSNDPVKDLSLVFGNHEST", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ::. *.*:::***** :. *:* ::: * *:: :. *. :. :**: ***:::::* .******* *: *. : : **. .* ***** *:.***.:*** :: : :* ::.: *:***::* :*:***:* :: : ** **** *: **: *::.: .:* .* *..**:**:*****:..** **.** *:.*:* :*:.* *** *.***:*** .**.. * : : : .::::****..:*****:*:*: :.:. ::::*. : *.: * .::::* .*::*:: . :: : .: * . . : . ", "identical_positions": 117, "similar_positions": 131, "identity": "25.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001020-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A585-1", "uniprot_id": "D4A585_RAT", "id": "D4A585-1", "name": "", "aln": "--------------MPEPGPDASGTASAPPPQPPPQPPAPKESPFSIRN----------------------------------------------------------------------------------------------------------------------------LLNGDHHRPPPKPQPPPRTLFAPASAAAAAAAAAAAAAKGALEGAAGFALSQVGDLAFPRFEIP--------------------------------------------AQRFALPAHYLERSPAWW---------YPYTLTPAGGHLPRPEASEKALLRDSSPASGTDRDSPDPLLKADPDHK--ELDSKSPDEIILEESDSEEGKKEGEAVPGAAGTTVGATAATPGSEDWKAGADSPEKKPA------------------------------------------------CRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEAANLS--HAAAQRIVRVPILYHENSAAEG-AAAAAGAPVPVSQPLLTFPHPVYYSHPVVSSVPLLRPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42581-1", "uniprot_id": "HMX3_MOUSE", "id": "P42581-1", "name": "Homeobox protein HMX3", "aln": "--------------MPEPGPDASGTASAPPPQPPPQPPAPKESPFSIRN----------------------------------------------------------------------------------------------------------------------------LLNGDHHRPPPKPQPPPRTLFAPASAAAAAAAAAAAAAKGALEGAAGFALSQVGDLAFPRFEIP--------------------------------------------AQRFALPAHYLERSPAWW---------YPYTLTPAGGHLPRPEASEKALLRDSSPASGTDRDSPEPLLKADPDHK--ELDSKSPDEIILEESDSEEGKKEGEAVPGAAGTTVGATTATPGSEDWKAGAESPEKKPA------------------------------------------------CRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEAANLS--HAAAQRIVRVPILYHENSAAEG-AAAAAGAPVPVSQPLLTFPHPVYYSHPVVSSVPLLRPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NHT5-1", "uniprot_id": "HMX3_HUMAN", "id": "A6NHT5-1", "name": "Homeobox protein HMX3", "aln": "--------------MPEPGPDAAGTASAQPQPPPPPPPAPKESPFSIKN----------------------------------------------------------------------------------------------------------------------------LLNGDHHRPPPKPQPPPRTLFAPASAAAAAAAAAAAAAKGALEGAAGFALSQVGDLAFPRFEIP--------------------------------------------AQRFALPAHYLERSPAWW---------YPYTLTPAGGHLPRPEASEKALLRDSSPASGTDRDSPEPLLKADPDHK--ELDSKSPDEIILEESDSEESKKEGEAAPGAAGASVGAAAATPGAEDWKKGAESPEKKPA------------------------------------------------CRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEAANLS--HAAAQRIVRVPILYHENSAAEGAAAAAAGAPVPVSQPLLTFPHPVYYSHPVVSSVPLLRPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q504H8-1", "uniprot_id": "HMX3_DANRE", "id": "Q504H8-1", "name": "Homeobox protein HMX3", "aln": "--------------MPETTQDTCASA--------------KDSPFFIKN----------------------------------------------------------------------------------------------------------------------------LLNSDSK--PSKPKP----ILAPT--------------KAGLDGS--FSLSQVGEINFPRFELP--------------------------------------------TQRFALPA-YLERASAWW---------YPYTLS-ASAHLHRTEAAQKA--RDSSPTTGTDRDSPELVLKSDPDAKDDEDDNKSGDEIVLEEGDTEDGKKEG------------------GIDDWKKSDDGADKKP-------------------------------------------------CRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEAANLS--HAAAQRIVRVPILYHENSASES--TNTAGN-VPVSQPLLTFPHPVYYSHPIVTSVPLLRPV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEI9-1", "uniprot_id": "HMX_DROME", "id": "Q9VEI9-1", "name": "Homeobox protein Hmx", "aln": "MSSSEAEVDISVVSSPEPSPLGAAARDSPLLARSPARSADGSSPPATPTHRSNTPNTAAGTPTTSASGGNHFHHSPSGGAVPPAVLHHHLQHHLSSLGSHPVALHHALHTFGHLHPAHGATHPALLQHALTPTGQQQQQQLQVQQQHQQSHVERLSPPMKSPERNGGDEVQGHSLNNNNSKALNHNNTCASAAAAAAAAAVAAANLSNNSNDSNGSSGGGGGKSTTGSNGFTSFSISSILSRSEPAKKNGAAGLITPIPQLPQPGAGGPQDAAMLSRLGFISQWGALAGRYAALCPPGWPWAPQRLPFHSPTHDSSSTNTTENPPSPTSMSPNNNNNNSNTTASSNQASKSPSHHPLHPLYHPLGSQQQQQQQQQHQQHPQQQQHPQQQQQQHPHQPTTPTSSSSSGGGSSLTHHPHPHLTGSHGGYLLPSSSNESDEEGEEIIEEDDGTDGPSDSSSPHGDGNSKRKKKTRTVFSRAQVFQLESTFDLKRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKRQLAAELEAANMANMAHAAQRLVRVPVLYHDGTTAGF-----VPPPPPHHHPMQYYAAARNTSPPRPPLSSLV---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **. ..: .** . **.: : :. *.: .. ... . * .*. *. *.:. :* **.. * ... * :. * :. : . .: .: :.. ... *.: *: .. .: :: : .: : : .. . . .. ::* ***********:**********:****************:*****************************:: ****:****:***:.::: . * :*: :. . * * . .*: ", "identical_positions": 102, "similar_positions": 90, "identity": "17.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001030-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q02548-1", "uniprot_id": "PAX5_HUMAN", "id": "Q02548-1", "name": "Paired box protein Pax-5", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MDLEKNYPTPRTSR-----TGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQ--------------------------------------QPPNQPVPASSHSIVSTGSVTQVSSVSTDSAG---------------------------SSYSISGILGITSPSADTNK-----------------RKRDEGIQESPVPNGHS------------LPGRDFLR------------KQMRGDL--------------------FTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQTTEYS-AMASLAGG----------LDDMKA---------------------NLASPTPADIGSSVPG------PQS------YPIVT-------------------------------------------------------------GRDLASTTLPGYPPHVPPAGQ-----------------------GSYSAPTLTG-----------MVPGSEFSGSPYSHPQYSSYNDSWRFPNP----------GLLG-------------------SPYYYSAAARGA--APPAAATAYDRH--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02650-1", "uniprot_id": "PAX5_MOUSE", "id": "Q02650-1", "name": "Paired box protein Pax-5", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MDLEKNYPTPRTIR-----TGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQ--------------------------------------QPPNQPVPASSHSIVSTGSVTQVSSVSTDSAG---------------------------SSYSISGILGITSPSADTNK-----------------RKRDEGIQESPVPNGHS------------LPGRDFLR------------KQMRGDL--------------------FTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQTTEYS-AMASLAGG----------LDDMKA---------------------NLTSPTPADIGSSVPG------PQS------YPIVT-------------------------------------------------------------GRDLASTTLPGYPPHVPPAGQ-----------------------GSYSAPTLTG-----------MVPGSEFSGSPYSHPQYSSYNDSWRFPNP----------GLLG-------------------SPYYYSPAARGA--APPAAATAYDRH--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LPW6-1", "uniprot_id": "A0ABK0LPW6_RAT", "id": "A0ABK0LPW6-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MEIHCKH-DPFASM-----HRHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQ--------------------------------------QPPNQPVPASSHSIVSTGSVTQVSSVSTDSAG---------------------------SSYSISGILGITSPSADTNK-----------------RKRDEGIQESPVPNGHS------------LPGRDFLR------------KQMRGDL--------------------FTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQTTEYS-AMASLAGS----------LDDMKA---------------------NLTSPTPADIGSSVPG------PQS------YPIVT-------------------------------------------------------------GRDLASTTLPGYPPHVPPAGQ-----------------------GSYSAPTLTG-----------MVPGSEFSGSPYSHPQYSSYNDSWRFPNP----------GLLG-------------------SPYYYSAAARGA--APPAAATAYDRH--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1QGF8-1", "uniprot_id": "F1QGF8_DANRE", "id": "F1QGF8-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MDLDQKGPSLRIGR-----SGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVDKIADYKRQNPTMFAWEIRDRLLAERVCDNDSVPSVSSINRIIRTKVQ--------------------------------------QPPGQSGAVSAHNLASTVAVTQVSAVTSDAAG---------------------------SSYSISGILGISSP-ADASK-----------------RKRDDPLQDSPLANGHS------------HSGRDFLR------------KQMRGEL--------------------FTPQQLE-------------------------TTDYS-AMASLAGG----------LEEMKN---------------------SLANQTGAELGSTVAG------PQS------YPLVS-------------------------------------------------------------GRDLASTTLPGYPPHVPPTGQ-----------------------GSYSTPSLTG-----------MVPGGDFSGSPYSHPQYSTYNESWRFANPSLLVFQQEYGSLLGSERAASSGLFPGQTPQPTGSPYYYSAATRGAGTAATATASAYDRH--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O16117-1", "uniprot_id": "O16117_DROME", "id": "O16117-1", "name": "", "aln": "MLIMDIQTSTHHIHGLGTHELQHRILHPHILHSTQEETLNTSTGQLEHDSQHLQQHHLTHHQQQDVSPTLHNLQNTRTGDSLSTTINTNQNQHGHQHLSGSNMYTSSQMEDKSKANKYDEYSSRTLSNISDANTTPSANNFITQSQGIEWITAMNDIQNGAEDSHSSQGSISGDGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKILSRYYETGSFKAGVIGGSKPKVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVPSVSSINRIVRNKAAEKAKHVHHHQQHHVSQSLGGGHIATESVDSSTGTIGEPQPPTSNSSANSVNTNVSASASVHASIPTSGTDSVQVSVGHINANSNETTHINSTAEQRTTGYSINGILGIQHGHHSHNNNNNSSVNNNNNTESSCKRKRIEAHDENHDTNIHSDNDDGKRQRMSTYSGDQLYTNIWSGKWCIKDDHKLLAELGNLTASTGNCPATYYEASNGFSTTPISGSGATASGNDTSMLYDSITTISQTQSSIYTPAIGPSIGTGSLTPLVPISMHEMKLSANSIQEQTVPPFYTALAFDGNYTSMTSLENCSSLVGQEHIVMPESSDSNTLCPISTRIVPDITETNSTRVKEPLTNSDGCSEDNNKEPEKSNSSQSSDHIASPHLHHIGEEQLRGNRRSNLNASTHPSSLIPLQPSGGSSLLNINPSENRSDVELNLSNNVGLYSTPTVLPSFNHYSAGCSSVVPGSDYAYNP-AYTQYGGAYGSYGYGTG---------SGLINSSYYYESGQTQSPLTHDLRSPLVATRANSLASAASPGSGSACTKSESSDIFLA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. ******************************:**********************.*******::.************* **: **:***:**************** :*.:*.**********:*.*. *** . ...: . : :.: :::.:..:. :.***.***** . .: *** : ::. .* ** .* :: ::: .:* *: :. :: *: *:.. * :.:** . :. * : *:: * *:* *: : :* ::* *. : *:* * **:*:: :***.::: .* ::.**. *: : . .*:. ** : * * *...:.:* : ", "identical_positions": 163, "similar_positions": 110, "identity": "19.09%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001031-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P26367-1", "uniprot_id": "PAX6_HUMAN", "id": "P26367-1", "name": "Paired box protein Pax-6", "aln": "----------------------MQNS---HSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQ-------------VSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMG---ADGMYDKLRMLNGQTGSWGTRPG--------WYPGTSVP-------GQPTQDGCQQQ------EGGGENTNSISSNGED------SDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQAS-----------NTPSHIPISSSFSTS-------VYQPIPQPTTPVSSFTSGSMLGRT--------DTALTNTYSALP----------------------PMPSFTMANNLP-----MQPPVPSQTSSYSCMLPT-----SPSVNGRSYDTYT--------PPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGS---EPDMSQYWPRLQ----------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63015-1", "uniprot_id": "PAX6_MOUSE", "id": "P63015-1", "name": "Paired box protein Pax-6", "aln": "----------------------MQNS---HSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQ-------------VSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMG---ADGMYDKLRMLNGQTGSWGTRPG--------WYPGTSVP-------GQPTQDGCQQQ------EGGGENTNSISSNGED------SDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQAS-----------NTPSHIPISSSFSTS-------VYQPIPQPTTPVSSFTSGSMLGRT--------DTALTNTYSALP----------------------PMPSFTMANNLP-----MQPPVPSQTSSYSCMLPT-----SPSVNGRSYDTYT--------PPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGS---EPDMSQYWPRLQ----------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63016-1", "uniprot_id": "PAX6_RAT", "id": "P63016-1", "name": "Paired box protein Pax-6", "aln": "----------------------MQNS---HSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQ-------------VSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMG---ADGMYDKLRMLNGQTGSWGTRPG--------WYPGTSVP-------GQPTQDGCQQQ------EGQGENTNSISSNGED------SDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQAS-----------NTPSHIPISSSFSTS-------VYQPIPQPTTPVSSFTSGSMLGRT--------DTALTNTYSALP----------------------PMPSFTMANNLP-----MQPPVPSQTSSYSCMLPT-----SPSVNGRSYDTYT--------PPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGS---EPDMSQYWPRLQ----------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0R4IQL7-1", "uniprot_id": "A0A0R4IQL7_DANRE", "id": "A0A0R4IQL7-1", "name": "Paired box protein Pax-6", "aln": "---MPQKEYHNQPTWESGVASMMQNS---HSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHDDAKVQLDNKNVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVGKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMG---ADGMYDKLRMLNGQSGTWGTRPG--------WYPGTSVP-------GQPNQDGCQQQ------DNGGENTNSISSNGED------SDETQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQAS-----------NSSSHIPISSSFNTS-------VYQAIPQPTTPVS-FTTGSMLGRP--------DTALTNTYTGLP----------------------PMPSFTMANNLP-----MQP---SQTSSYSCMLPS-----SPSVNGRSFDTYT--------PPHMQAHMNSQTMATSGTASTGLISPGVSVPVQVPGT---EPDMSQYWSRLQ----------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A6H2EG63-1", "uniprot_id": "A0A6H2EG63_DROME", "id": "A0A6H2EG63-1", "name": "", "aln": "MMLTTEHIMHGHPHSSVGQSTLFGCSTAGHSGINQLGGVYVNGRPLPDSTRQKIVELAHSGARPCDISRILQ-------------VSNGCVSKILGRYYETGSIKPRAIGGSKPRVATTPVVQKIADYKRECPSIFAWEIRDRLLSEQVCNSDNIPSVSSINRVLRNLASQKEQQAQQQNESVYEKLRMFNGQTGGWAWYPSNTTTAHLTLPPAASVVTSPANLSGQADRDDVQKRELQFSVEVSHTNSHDSTSDGNSEHNSSGDEDSQMRLRLKRKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGLPEARIQVWFSNRRAKWRREEKMRTQRRSADTVDGSGRTSTANNPSGTTASSSVATSNNSTPGIVNSAINVAERTSSALVSNSLPEASNGPTVLGGEANTTHTSSESPPLQPAAPRLPLNSGFNTMYSSIPQPIATMAENYNSSLGSMTPSCLQQRDAYPYMFHDPLSLGSPYVSAHHRNTACNPSAAHQQPPQHGVYTNSSPMPSS---NTGVISAGVSVPVQISTQNVSDLTGSNYWPRLQXSSIFGSPLDHLSKATAAAIIAAQAAEKSHKHRKEHSIVSIHTTKRKKNPPSLKRQTTCCSSRYLNMTFGAGKDVDVVIGQGLIVSLTPHISGKPELFGSPNVNYHQDFQVI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ***:******:******************************** *******************:*************. ** ***:******************** **..******************:*:* . :.:*:****:***:* *. *. *.:** **. :*. *:: : *::. :*:*:. .:::****:************::***::******************** **.**********************:*.***.*. *..* . ***. ** * ..* . . * :.:.*: . :: *:* : * * * ***:* * * .* .:*. *: ** *..: :* **: .: **..* :* .**:**.*******:. : *:**.*** ", "identical_positions": 262, "similar_positions": 90, "identity": "39.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001101-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29476-1", "uniprot_id": "NOS1_RAT", "id": "P29476-1", "name": "Nitric oxide synthase 1", "aln": "MEENTFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQAGDIILAVNDRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTIRVTQPLGPP--TKAVDLSHQPSASKDQSLAVDRVTGLGNGPQHAQGHGQGAGSVSQANGVA-----IDPTMKSTKANLQDIGEHDELLKEIEPVLSILNSGSKATNRGGPAKAEMKDTGIQVDRDLDGKSHKAPPLGGDNDRVFNDLWGKDNVPVILNNPYSEKEQSPTSGKQSPTK---NGSPSRCPRFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPSQHTRKPEDVRTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKGTNGTP---TKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHAFDAKAMSMEEYDIVHLEHEALVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQEERKSYKVR----FNSVSSYSDSRKSSGDGPDLRDNFEST-------------GPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKPNNSLISNDRSWKRNKFRLTYVAEAPDLTQGLSNVHKKRVSAARLLSRQN--LQSPKFSRSTIFVRLHTNGNQELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPANHVVKVEMLEERNTALGVISNWKDESRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATNEKEKQRLLVLSKGLQEYEEWKWGKNPTMVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYHTRDGEGPVHHGVCSSWLNRIQADDVVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMNPCP-MVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDRPKKYVQDVLQEQLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSEEDAGVFISRLRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDADEVFSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0J4-1", "uniprot_id": "NOS1_MOUSE", "id": "Q9Z0J4-1", "name": "Nitric oxide synthase 1", "aln": "MEEHTFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQAGDIILAVNDRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTIRVTQPLGTP--TKAVDLSRQPSASKDQPLAVDRVPGPSNGPQHAQGRGQGAGSVSQANGVA-----IDPTMKNTKANLQDSGEQDELLKEIEPVLSILTGGGKAVNRGGPAKAEMKDTGIQVDRDLDGKLHKAPPLGGENDRVFNDLWGKGNVPVVLNNPYSENEQSPASGKQSPTK---NGSPSRCPRFLKVKNWETDVVLTDTLHLKSTLETGCTEQICMGSIMLPSHHIRKSEDVRTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVEFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKGTNGTP---TKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHAFDAKAMSMEEYDIVHLEHEALVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQEERKSYKVR----FNSVSSYSDSRKSSGDGPDLRDNFEST-------------GPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTYVAEAPELTQGLSNVHKKRVSAARLLSRQN--LQSPKSSRSTIFVRLHTNGNQELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPANHVVKVEMLEERNTALGVISNWKDESRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATNEKEKQRLLVLSKGLQEYEEWKWGKNPTMVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYHTRDGEGPVHHGVCSSWLNRIQADDVVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMNPCP-MVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDRPKKYVQDVLQEQLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSEEDAGVFISRLRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29475-1", "uniprot_id": "NOS1_HUMAN", "id": "P29475-1", "name": "Nitric oxide synthase 1", "aln": "MEDHMFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQAGDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTIRVTQPLGPP--TKAVDLSHQPPAGKEQPLAVDGASGPGNGPQHAYDDGQEAGSLPHANGLAPRPPGQDPAKKATRVSLQGRGENNELLKEIEPVLSLLTSGSRGVKGGAPAKAEMKDMGIQVDRDLDGKSHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPTSGKQSPTK---NGSPSKCPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRPEDVRTKGQLFPLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKGTNGTP---TKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQEERKSYKVR----FNSVSSYSDSQKSSGDGPDLRDNFESA-------------GPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTFVAEAPELTQGLSNVHKKRVSAARLLSRQN--LQSPKSSRSTIFVRLHTNGSQELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPVNQMVKVELLEERNTALGVISNWTDELRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSWLNRIQADELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMNPCP-MVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEQLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRMRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IQG7-1", "uniprot_id": "A0A0R4IQG7_DANRE", "id": "A0A0R4IQG7-1", "name": "Nitric oxide synthase", "aln": "MQESEPSVCQLQPNIISVRLFKRKIGGLGFLVKQRVCKPPVIVSDLIRGGAAEECGLVQVGDIVLAVNNKPLVDMSYERALETLKNVSPESHAVLILRGPEGFTTHLETTLSSDGKTKTIRVTRPVNPAQSRPCERCSPLTPNMTKELRAIENLSSSSTPRKESRDDKPLIPLLSQDSLLR--------EGGHAGLLLNGVEDNNDLLKEIEPVLKLIKNSKKEINGEGQRVIDRKDAEVQVERDLGVGNGQNAQLASDNDRVFDDLWRKDNMPTVLNNPYSESDKPQSYERVSPTKAVQNGSPSKCPRFMKVKNWETGALYNDTLHHSSSKVPICTEHVCIGSIMVPNQHAHKPDEDRRKEELLPLATDFIDQYYTSIKRCCSKAHVDRLEEVKKEIETSGTYQLKDTELIYGAKHAWRNAARCVGRIQWSKLQVFDARDCTTAHGMFNYICNHIKYATNKGNLRSAITIFPQKTDGKHDFRVWNSQLIRYAGYKQPDGSILGDPASVELTEICMQQGWKAPKGRFDVLPLLLQANGNDPELFEIPDDLVLEVPIIHPKFEWFKELNLKWYGLPAVSNMLLEIGGLEFTACPFSGWYMGTEIGVRDFCDSSRYNILEEVATMMGLDTRKTSSLWKDQALVEINIAVLYSYQMSKVTIVDHHSATESFMKHMENEYRVRGGCPGDWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKGVNGTP---TKKRAIGFKKLAKAVKFSAKLMGQAMAKRVKATILFATETGKSQDYAKTLCEIFKHAFDAKVMSMDEYDTVDLEHETLVIVVTSTFGNGDPPENGEKFGAALMEMRHPTTSVEDRKTYKVR----FNSVSSYSDTRKSSSDEPESKANFEST-------------GPLANVRFSVFGLGSRAYPHFCAFAHAVDTLFEELGGERILRMGEGDELCGQEESFRTWAKKVFKAACDVFCVGDDVNIEKANDSLISNDRSWKKSKFRMTYTAEAPTLTQALYSIHKKKVYGAKVVQRQN--LQSARSNRLTIFVRLDANNHESLKYLPGDHLGVFPGNNEDLVTTLIEKLEDAPPVNQIVKVEFLEERNTALGVISNWTDESRIPPCTIYQAFKYFLDITTPPSPVLLQQFAPLATNEKQRKRLEVLSKGLQEYEEWKWYNNPTMVEVLEEFPSLQIPSTLLLTQLPLLQPRYYSISSSPDLYPGEIHLTVAVVSYRPRDGEGPIHHGVCSSWLNSLDEGDTVPCFVRGAPSFRMPKDSQVPCILIGPGTGIAPFRAFWQQRQYDVENKGIKACP-MILVFGCRQSQIDHIYKEQTIQAKNKEVFKELYTAYSREPGRPKKYVQDVLREQLSETVYKCLREEGGHIYVCGDVTMAGDVLKTVQQIFKLHGNMSLEDAGFYISKLRDENRYHEDIFGVTLRTYEVTNRLRSESIAYIEESKKDIDEVFCS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q27571-1", "uniprot_id": "NOS_DROME", "id": "Q27571-1", "name": "Nitric oxide synthase", "aln": "----------------MSQHFTSIFENLRFVTIKRSTN------------AQQQQ---QQQQQQLQQQQQQLQQQKAQTQQQNSRKIKT--QATPTLNG-NGLLSGNPNGGGGDSSP-SHEVDHP-----------------GGAQGAQAAGGLPSSSGTPLRHHKR---ASISTASPPIR-----------------ERRGTNTSIVVELD------GSGSGSGSGGG---------GVGVGQGAGCPPSGSCTASGKSSRELSPSPKNQQQPRKMSQDYRSRAGSFMHLDD-------EGRSLLMRKPMRLKNIEGRPEVYDTLHCKGREILSCSKATCTSSIMN---IGNAAVEARKSDLILEHAKDFLEQYFTSIKRTSSTAHETRWKQVRQSIETTGHYQLTETELIYGAKLAWRNSSRCIGRIQWSKLQVFDCRYVTTTSGMFEAICNHIKYATNKGNLRSAITIFPQRTDAKHDYRIWNNQLISYAGYKQADGKIIGDPMNVEFTEVCTKLGWKSKGSEWDILPLVVSANGHDPDYFDYPPELILEVPLTHPKFEWFSDLGLRWYALPAVSSMLFDVGGIQFTATTFSGWYMSTEIGSRNLCDTNRRNMLETVALKMQLDTRTPTSLWKDKAVVEMNIAVLHSYQSRNVTIVDHHTASESFMKHFENESKLRNGCPADWIWIVPPLSGSITPVFHQEMALYYLKPSFEYQDPAWRTHVWKKGRGESKGKKPRRKFNFKQIARAVKFTSKLFGRALSKRIKATVLYATETGKSEQYAKQLCELLGHAFNAQIYCMSDYDISSIEHEALLIVVASTFGNGDPPENGELFSQELYAMRVQESSEHGLQDSSIGSSKSFMKASSRQEFMKLPLQQVKRIDRWDSLRGSTSDTFTEETFGPLSNVRFAVFALGSSAYPNFCAFGQYVDNILGELGGERLLRVAYGDEMCGQEQSFRKWAPEVFKLACETFCLDPEESLSDASLALQND--SLTVNTVRLVPSANKGSLDSSLSKYHNKKVHCCKAKAKPHNLTRLSEGAKTTMLLEICAPG---LEYEPGDHVGIFPANRTELVDGLLNRLVGVDNPDEVLQLQLLKEKQTSNGIFKCWEPHDKIPPDTLRNLLARFFDLTTPPSRQLLTLLAGFCEDTADKERLELLVNDSSAYEDWRHWRLPHLLDVLEEFPSCRPPAPLLLAQLTPLQPRFYSISSSPRRVSDEIHLTVAIVKYRCEDGQGDERYGVCSNYLSGLRADDELFMFVRSALGFHLPSDRSRPIILIGPGTGIAPFRSFWQEFQVLSDLDPTAKLPKMWLFFGCRNRDVD-LYAEEKAELQKDQILDRVFLALSREQAIPKTYVQDLIEQEFDS-LYQLIVQERGHIYVCGDVTMAEHVYQTIRKCIAGKEQKSEAEVETFLLTLRDESRYHEDIFGITLRTAEIHTKSR--ATARIRMASQP-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. . .* *:. :* : * :: * : * : : * : . : : : : . :.. *.* :*: : . .*... : .* :* . * .. . . . : : : .:: *:: .. . . : * :. . . ...* :. : : * :.: * . . :* . : :::** * **** .. *:: * .*** . . : * . :: *.:*::**::**** *.** * ::*.:.*:::. ***.:******** ****::**:************.* **: ***: ****:******************:**.***:*:**.*** ******.**. :*** .*::**:* : ***. ..:*:***::.***:**: *: * :*:****: ****:**.:*.*:**.*****.**:::**::*:* .******.**** *: **..* *:** ** * ** *..:*****:*:**:*****:*:* :*******:*:***:**:*** : *.***.**:*****:************ * *.****** .*.***** .* . . :* :.**::*.****::**:*:*::**:***:*:*******: *** ***:: ***:*: .*.:** :***:*::**:************* *. * ** : . : .: * ..** .: * . : . .::* ***:****:**.*** ***:****.: **.:: ******:*:: ***:****::**.** :*** **:.**:. : .:.... :* .: * . ...*:. *: * ..* . *:*:* .: : : : .. : *:::.: : . *:* ****:*:**.*. :** *:::* .. :.::::::*:*::*: *::. * . ::** *: : : ::*:****: * :* :. . :::** :* :. . **:*: . * :::******* : *:.***:**. ****:******* ..*:*****:*.*: .**:* ::****.:*. : .: : ***.* .*::* : . * **:**********:***: * : . * * *.****: .:* :* *:. : ::. :: .:: * *** **.****::.::: . :*: : :: ************ .* ::::: : : : * :. :: :**:.********:**** *: .: * : * *. :.: ", "identical_positions": 537, "similar_positions": 425, "identity": "36.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001103-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LYL9-1", "uniprot_id": "SOX9_RAT", "id": "F1LYL9-1", "name": "Transcription factor SOX-9", "aln": "MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDLK--KESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKS-VKNGQAEAEEATEQTHISPNAIFKALQ------------ADSPHSSSGMSEVHSPGEHSGQSQGPP-------------TPPTTPKTDVQAGKVDLKREGRPLAE-GGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPP-NGHPGVPATHGQVSYTGSYGISSTAPTPATAGHVWMSKQQAPPPPPQQPPQAPQAPQAPPQ-QQAPPQPQQAPQQQ-QAHTLTTLS-SEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQISYSPFN---LPHYNPSYPTITRSQYDYTDHQN---SGSYYSHAAGQGSGLYSTFTYMNPAQRPMYTPIADTSGVPSIPQT-HSPQHWEQ-PVYTQLTRP-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q04887-1", "uniprot_id": "SOX9_MOUSE", "id": "Q04887-1", "name": "Transcription factor SOX-9", "aln": "MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDLK--KESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKS-VKNGQAEAEEATEQTHISPNAIFKALQ------------ADSPHSSSGMSEVHSPGEHSGQSQGPP-------------TPPTTPKTDVQAGKVDLKREGRPLAE-GGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPP-NGHPGVPATHGQVTYTGSYGISSTAPTPATAGHVWMSKQQAPPPPPQQPPQAPQAPQAPPQ-QQAPPQQPQAPQQQ-QAHTLTTLS-SEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQISYSPFN---LPHYSPSYPPITRSQYDYADHQN---SGSYYSHAAGQGSGLYSTFTYMNPAQRPMYTPIADTSGVPSIPQT-HSPQHWEQ-PVYTQLTRP-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48436-1", "uniprot_id": "SOX9_HUMAN", "id": "P48436-1", "name": "Transcription factor SOX-9", "aln": "MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDLK--KESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKS-VKNGQAEAEEATEQTHISPNAIFKALQ------------ADSPHSSSGMSEVHSPGEHSGQSQGPP-------------TPPTTPKTDVQPGKADLKREGRPLPE-GGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPP-NGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPPQPQAAPPQQPAAPPQQPQAHTLTTLS-SEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQIAYSPFN---LPHYSPSYPPITRSQYDYTDHQN---SSSYYSHAAGQGTGLYSTFTYMNPAQRPMYTPIADTSGVPSIPQT-HSPQHWEQ-PVYTQLTRP-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DFH2-1", "uniprot_id": "Q9DFH2_DANRE", "id": "Q9DFH2-1", "name": "", "aln": "MNLLDPYLKMTDEQEKCLSDAPSPSMSEDSAGSPCPSASGSDTENTRPAENSLLAADGTLGDFKKDEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNEVEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKS-VKNGQSESEDGSEQTHISPNAIFKALQQ-----------ADSPASS--MGEVHSPSEHSGQSQGPP-------------TPPTTPKTDTQPGKADLKREARPLQENTGRPLSINFQDVDIGELSSDVI---ETFDVNEFDQYLPP-NGHQNAP-------YAGGY-------------AAWMTKPQNGSP---------------------------------QSSQLTPLNPAEPDQPRTTHIKTEQLSPSHYNEQQ-GSPQHISYGSFNVQHLQHYSTSFPSITRAQYDYSDSHQGG-ASSYYTHAGGQSSGLYSTFSYMSSSQRPMYTPIADSTGVPSIPQSNHSPQHWDQQPVYTQLSRP-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VA17-1", "uniprot_id": "Q9VA17_DROME", "id": "Q9VA17-1", "name": "", "aln": "--------------------------MSDSSSSNCSKDRAKPVETLVLANYALKAEQKKAQGQGGRKEDER---ITTAVMKVLEGYDWNLVQASAKAP-TDRKKEHIKRPMNAFMVWAQAARRVMSKQYPHLQNSELSKSLGKLWKNLKDSDKKPFMEFAEKLRMTHKQEHPDYKYQPRRKKARVLPSQQSGEGGSPGPEMTLSATMGSSGKPRSSNSNGQRRAGKGNAAADLGSCASTISHANVGSNSSDVFSNEAFMKSLNSACAASLMEQSLIETGLDSPCSTASSMSSLTPPATPYNVAPSNAKASAANNPSLLLRQLSEPVANAGDGYGVLLEAGREYVAIGEVNYQGQSAGVQSGAEGGGAGQEMDFLENINGYGGYTGSRVSYPAYSYPANGGHFATEEQQQQQALQASEALNYKPAAADIDPKEIDQYFMDQMLPMTQHHHPHHTHPLHHPLHHSPPLNSSASLSSACSSASSQQPVAEYYEHLGYSPAASSASQNPNFGPQQPYANGAASMTPTLGDPAPQQELQSQQQEQQHQNPSQHHLWGTYTYVNP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .**:.* *.. .. .*. : :: : :**: * ** :**:****.** ..:. :.::* *:**************** ::.*****:*:****:*****: *:: :*:**:* **:**: **::**********:*: * .* ..* .: ..:: .* : : *.. :: :.. *. .*:. ..... :. ::. : . :..*. . . . . :* .: .:.. . : : : . :*: * : : * . : :. :.*..:::. . .: : :: .: .. *:... . : . :. . ..** * . . :. :: . .*:* . *. : . . * . :. * :* : : :: ", "identical_positions": 96, "similar_positions": 160, "identity": "17.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001103-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TBJ5-1", "uniprot_id": "FEZF2_HUMAN", "id": "Q8TBJ5-1", "name": "Fez family zinc finger protein 2", "aln": "--------------------MASSAS--LETMVPPACPRAG---ASPATSK---TLAFSIERIMAKTSEPRAPFEPRPG----ALEADGSQGKKLLNLCSPLPCMIPLQPLGYEVPSKTLLSYSELWKSSLRAGGGGGGGGGGGGGGGGAPVCGASGLCKTNCGVCCKAELGLAPSALPAGRVIKPQVINQAVGLPASGSLYYFNYLDSTAYPPSELLS---GHLFPSGLLNAQAPAALAAHPKLFLLENAKLAGLAADKFPHPAPYPHKERLPAPLEQVLKENSALTAERGGVKGHS---------KLPGGSADGKPKNFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHIRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQYKCTICNKAFHQVYNLTFHMHTHNDKKPFTCATCGKGFCRNFDLKKHVRKLHDS---VGP-AAPSAKDLTRTVQS-----------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9ESP5-1", "uniprot_id": "FEZF2_MOUSE", "id": "Q9ESP5-1", "name": "Fez family zinc finger protein 2", "aln": "--------------------MASSAS--LETMVPPACPRAG---ASPATSK---TLAFSIERIMAKTSEPRAPFEPRPA----ALEADSSQSKKLLNLCSPLPCMIPLQPLGYEVPSKTLLSYSEFWKSSLRAGGGGGGGSGGG-----APVCGASGLCKTNCGVCCKAELGLAPSALPAGRVIKPQVINQAVGLPASGSLYYFNYLDSTAYPPSELLG---GHLFPSGLLNAQAPTSLAAHPKLFLLENAKLASLAADKFPHPASYPHKERLHAPLEQVLKENSALTAERGGVKSHS---------KLPGGSTDSKPKNFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHIRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQYKCTICNKAFHQVYNLTFHMHTHNDKKPFTCATCGKGFCRNFDLKKHVRKLHDS---VGPTATPSAKDLARTVQS-----------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q804Q5-1", "uniprot_id": "FEZF2_DANRE", "id": "Q804Q5-1", "name": "Fez family zinc finger protein 2", "aln": "--------------------MASSLP--LETVMS--CPRLDDRSGATAAPK---SLAFSIDRIMSKTSEPKA-----------AAAEERSEGKKTVGLCSPIPCMIPIQPFSYDLQAKALMNYSEFWKVNFRG-----------------ALCTSAAMCKTNCGVCSKADAGIKHSVLPGTRVIKPQVIHQALAMPANGSLCYFNYLDS-AY-QSELLS---GHLFSSAIANSQA-QAISAHQKLLLLENAKLACVSPEKFPTPQ-YPHKEHLPGQLDQIVRESHNLTE-KNGVKAHS---------KTNNCSSDGKPKNFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHIRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQYKCSICSKAFHQIYNLTFHMHTHNDKKPFTCGTCGKGFCRNFDLKKHIRKLHDN---ANC--LSGGNDSSRGHQN-----------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQ56-1", "uniprot_id": "ERM_DROME", "id": "Q9VQ56-1", "name": "Fez family zinc finger protein erm", "aln": "MVYFSPRGMQPCSPAGEIAMMPPSKSPVMESAASEQNPAQQSQQQDEQSAKRACPLKFSIAKIMEPDHRPSQVPPPQPAPVSFATNDDDEDEDPEIDADSERSCS-PIEVISLD-QSPSTVNYDSAFKKYVPGPCSGATSSVASPPSTAAVQQFVSSRHQELLSQYPLLYYAPNQLMCAAAAAQYAALTAQQQSLASAAHLSSFTASLNASLHHSQSLRRNLGHPLAAAAAVAAVAQSQAVPNLQHTLEKSPVAQRTAQ-SSGLQANLKRKRSPQDQGEVTPPPASTATSATGARSRSPSPQGSIEDSSPGSASGGKPKTFSCLECGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTSEKPHKCQTCGKAFNRSSTLNTHSRIHAGYKPFVCEYCGKGFHQKGNYKNHKLTHSGEKAYKCNICNKAFHQVYNLTFHMHTHNDKKPYTCRVCAKGFCRNFDLKKHMRKLHEIGGDLDDLDMPPTYDRRREYTRREPLASGYGQASGQLTPDSSSGSMSPPINVTTPPLSSGETSNPAWPRSAVSQYPPGGFHHQLGVAPPHDYPSGSAFLQLQPQQPHPQSQQHHQQQQRLSETFIAKVF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *..* . :*: . * :.* .* *** :** .* * : .: . :. * .* *:: :. : : : :.*.. :* . . :. : . . .. . . : * .:.: . * *. . : *: * ** :.:. : . : :. **:: :* :.: . :::: :: : *.:.:* . . ::..***.*:* ***********************************************.******: ************** ************:********************** ***.**.*****:***************:** .*.************:****: . . * * ", "identical_positions": 182, "similar_positions": 99, "identity": "29.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001103-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P22443-1", "uniprot_id": "CP19A_RAT", "id": "P22443-1", "name": "Aromatase", "aln": "MFLEMLNPMHYNVTIMVPETVPVSAMPLLLIMGLLLL-IRNCESSSSIPGPGYCLGIGPLISHGRFLWMGIGSACNYYNKMYGEFMRVWISGEETLIISK--SSSMVHVMKHSNYISRFGSKRGLQCIGMHENGIIFNNNPSLWRTVRPFFMKALTGPGLIRMVEVCVESIKQHLDRLGDVTDNSGYVDVVTLMRHIMLDTSNTLFLGIPLDES---------SIVKKIQGYFNAWQALLIKPNIFFKISW------LYRKYERSVKDLKDEIEILVEKKRQKVSSAEK-------------LEDCMDFATDLIFAERRGD--LTKENVNQCILEMLIAAPDTMSVTLYVMLLLIAEYPEVETAILKEIHTVVG---DRDIRIGDVQNLKVVENFINESLRYQPVVDLVMRRALEDDVIDGYPVKKGTNIILN-IGRMHRLEYFPKPNEFTLENFEK-----NVPYRYFQPFGFGPRSCAGKYIAMVMMKVVLVTLLKRFHVKTLQKRCIENMPKNNDLSLHL-DEDSPIVEIIFRHIFNTPFLQCLYISL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28649-1", "uniprot_id": "CP19A_MOUSE", "id": "P28649-1", "name": "Aromatase", "aln": "MFLEMLNPMQYNVTIMVPETVTVSAMPLLLIMGLLLL-IWNCESSSSIPGPGYCLGIGPLISHGRFLWMGIGSACNYYNKMYGEFMRVWISGEETLIISK--SSSMFHVMKHSHYISRFGSKRGLQCIGMHENGIIFNNNPSLWRTIRPFFMKALTGPGLVRMVEVCVESIKQHLDRLGEVTDTSGYVDVLTLMRHIMLDTSNMLFLGIPLDES---------AIVKKIQGYFNAWQALLIKPNIFFKISW------LYRKYERSVKDLKDEIAVLVEKKRHKVSTAEK-------------LEDCMDFATDLIFAERRGD--LTKENVNQCILEMLIAAPDTMSVTLYFMLLLVAEYPEVEAAILKEIHTVVG---DRDIKIEDIQNLKVVENFINESMRYQPVVDLVMRRALEDDVIDGYPVKKGTNIILN-IGRMHRLEYFPKPNEFTLENFEK-----NVPYRYFQPFGFGPRGCAGKYIAMVMMKVVLVTLLRRFQVKTLQKRCIENIPKKNDLSLHP-NEDRHLVEIIFSPRNSDKYLQQ--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11511-1", "uniprot_id": "CP19A_HUMAN", "id": "P11511-1", "name": "Aromatase", "aln": "MVLEMLNPIHYNITSIVPEAMPAATMPVLLLTGLFLL-VWNYEGTSSIPGPGYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISK--SSSMFHIMKHNHYSSRFGSKLGLQCIGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVRMVTVCAESLKTHLDRLEEVTNESGYVDVLTLLRRVMLDTSNTLFLRIPLDES---------AIVVKIQGYFDAWQALLIKPDIFFKISW------LYKKYEKSVKDLKDAIEVLIAEKRRRISTEEK-------------LEECMDFATELILAEKRGD--LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG---ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILN-IGRMHRLEFFPKPNEFTLENFAK-----NVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHP-DETKNMLEMIFTPRNSDRCLEH--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PGW6-1", "uniprot_id": "A0A8M9PGW6_DANRE", "id": "A0A8M9PGW6-1", "name": "aromatase", "aln": "-MMEHVVKDAVNIGAVVQGTLLLLTGTLMLILLHRIFGVKNWRNQSALPGPGWWLGLGPVLSYSRFLWMGIGTACNYYNEKYGSIARVWINGEETVILSKQVSSAVYHVLKSNNYTGRFASAKGLQCIGMFEQGIIFNSNIAKWKKVRTYFTKALTGPGLQKSVEVCVSATNRQLDVLQEFTDASGHVDVLNLLRCIVVDVSNRLFLRIPLNEK---------ELLIKIHRYFSTWQTVLIQPDIFFKLDF------VYRKYHLAAKELQDEMGKLVEQKRQAINNTEK-------------LDE-MDFATELIFAQNHDE--LSVDDVRQCVLEMVIAAPDTLSISLFFMLLLLKQNSAVEEQIVQEIQSQIG---SRDVESADLQKLNVLERFIKESLRYHPVVDFIMRQSLEDDYIDGYRVAKGTNLILN-IGRMHKTEFFKKPNEFSLENFEN-----TVPSRYFQPFGCGPRACVGKHIAMVMTKAILVTMLSRFTVCPRHGCTISTIRQTNNLSMQPVEEDPDCLAMRFIPRAQNSNGETADNRTSKE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVN6-1", "uniprot_id": "CP312_DROME", "id": "Q9VVN6-1", "name": "Probable cytochrome P450 312a1", "aln": "-----MFWLGFGLLLLALSLYLLYVFERQSRIDRLTH---KWPAPPALPFIGHLHILAKLVGPHPLRRA----TEMINEHLHDHRAKLWMGTKLYLVDCN--PKDIQALCSAQQLLQKTNDYRVFENWLCEG---LFTSGFEKWSHRRKIVMPAFNYTMIKQFVAVFEKQSRILLTNVAKFAESGDQIDFLQLISCFTLDTICETALGVSVGSQSSAKSEYLDAVKSILVIIDKRLKNIFYRNSFIFKRTS------HYKREQELIKTLHGFTEGIIQKRIDEINQDAENRNYQSSDAELDGVKRTLCFLDTLLLSKGPDGKPLTVKDIREEVDTIIFGGFDLTATTLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPISIEQVRQLEFLEACIKETLRMYPSGPLTARKATANCTINDFFIPKGSDVIISPIYMGRCKDFFPDPMVFKPDRWAIGA-EPKIEATTFIPFMAGARSCMGQRYAMVMLKMVLAHLLRNFLFEPLGERQVK-LKLNFVITLHT------VEPYLCRAKNLD-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O46054-1", "uniprot_id": "C4AE1_DROME", "id": "O46054-1", "name": "Cytochrome P450 4ae1", "aln": "--------------MLVVLLVALLVTRLVASLFRLALKELRHPLQGVVPSVSRVPLLGAAWQMRSFQPDNLHDKFAEYVKRFGRSFMGTVLGHVVMVTAE--PRHIDALLQGQHQLKKGTMYFALRGWLGDG---LLLSRGKEWHTMRKIITPTFHFSILEQFVEVFDRQSSILVERLRTLSYGNEVVNIYPLVGLAALDIITETAMGVNVDAQG-----ADSEVVHAVKDLTNILATRFMRPHLLFPHLFRLCWPSGFRKQQAGVICLHEFTNGIIEQRRRLLAREANQ----------DKPTKPHALLDTLLRATVDGQ-PLTDKQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEELRMHYGQDLFRGVILSDFATLPYLSCVVKESLRLYPPIPAVARCLEKDLVIDEGYIPVGTNVVVLLWQLLRDEAIFTDPLVFQPERHLGEE-APRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHYQLLPMG----ADVEPSIKIVLRS----KSGVNVGLRPRLY--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V4T3-1", "uniprot_id": "C4AD1_DROME", "id": "Q9V4T3-1", "name": "Probable cytochrome P450 4ad1", "aln": "-------------MFLIAIAIILATILVFKGVRIFNYIDHMAGIMEMIPGPTPYPFVGNLFQFGLKPAEYPKKVLQYCRKYDFQGFRSLVFLQYHMMLSD--PAEIQNILSSSSLLYKEHLYSFLRPWLGDG---LLTSSGARWLKHQKLYAPAFERSAIEGYLRVVHRTGGQFVQKLDVLSDTQEVFDAQELVAKCTLDIVCENATGQDSSSLNGETSDLHGAIKDLCDVVQERTFSIVKRFDALFRLTS------YYMKQRRALSLLRSELNRIISQRRHQLAAENTCQ---------QGQPINKPFLDVLLTAKLDGK-VLKEREIIEEVSTFIFTGHDPIAAAISFTLYTLSRHSEIQQKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRETLRLYPSVPLIARTNRNPIDINGTKVAKCTTVIMCLIAMGYNEKYFDDPCTFRPERFENPTGNVGIEAFKSVPFSAGPRRCIAEKFAMYQMKALLSQLLRRFEILPAVDGLPPGINDHSREDCVPQSEYDPVLNIRVTLKSENGIQIRLRKR----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :* :. . : . :: .. . : : . . : :. :: . * : :: . : : * : : .: .: *: :* . : . . : :* : : . *: :: :: : : *: : . *. :: : : ::: . * : :: . : : : :* * . : :. : *::* * * *: : : ::: * .* * :. : ** *.* * .: *: * :: :: .: . . : ", "identical_positions": 27, "similar_positions": 103, "identity": "4.87%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001103-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1L1-1", "uniprot_id": "CLD7_RAT", "id": "Q9Z1L1-1", "name": "Claudin-7", "aln": "MANSGLQLLGFSMAMLGWVGLIASTAIPQWQMSSYAGDNIITAQAMYKGLWMECVTQSTGMMSCKMYDSVLALPAATQATRALMIVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMTGGIIFIVAGLAALVACSWIGHQIVTDFYNPLTPMNIKYEFGPAIFIGWAGSALVLLGGALLSCSCPGSESKAAY----RAPRSYPKSNSSKEYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z261-1", "uniprot_id": "CLD7_MOUSE", "id": "Q9Z261-1", "name": "Claudin-7", "aln": "MANSGLQLLGFSMAMLGWVGLIASTAIPQWQMSSYAGDNIITAQAMYKGLWMECVTQSTGMMSCKMYDSVLALPGALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKAKKARIAMTGGIVFIVAGLAALVACSWIGHQIVTDFYNPLTPMNVKYEFGPAIFIGWAGSALVLLGGALLSCSCPGSESKAAY----RAPRSYPKSNSSKEYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95471-1", "uniprot_id": "CLD7_HUMAN", "id": "O95471-1", "name": "Claudin-7", "aln": "MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMGGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGALLSCSCPGNESKAGY----RVPRSYPKSNSSKEYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9YH92-1", "uniprot_id": "CLD7B_DANRE", "id": "Q9YH92-1", "name": "Claudin-7-B", "aln": "MAHKGLQLLGFTLSLLGLIGLIIGTIMPQWKMSAYVGDNIITAIAMYQGLWMSCAYQSTGQQQCKVYDSVLQLDSALQATRALMVVAILLTVAGLGVASMGMKCTNCGGDDKVKKSRIAMTGGIILSVGALCSIVACGWFTSQIIRDFYNPFTPVNTKYEFGAAIFIAWAGAFLDIMGGGMLASSCSKGQSSPNYPKSSRPVKSSRPPSSSKEYV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:.*******::::** :**: * :***:**:*.******* ***:****.*. **** .**:***** * .* *******:*:::* . .: **:******.******.**:**** ***:: *..*.::***.* **: *****: * * *****.****.***: * ::**.:*:.**. .:*.. * * :* ..******", "identical_positions": 123, "similar_positions": 56, "identity": "57.21%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001106-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ADM6-1", "uniprot_id": "A0A8I6ADM6_RAT", "id": "A0A8I6ADM6-1", "name": "Protein Wnt", "aln": "MAPLGYLLVL-CSLKQALGSYPIWWSLAVGPQYSSLSTQPILCASIPGLVPKQLRFCRNYVEIMPSVAEGVKAGIQECQHQFRGRRWNCTTVSNSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGSAAICGCSSRLQGSPGEGWKWGGCSEDIEFGGMVSREFADARENRPDARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRTIGDFLKDKYDSASEMVVEKHRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNARTERRREKCHCVFHWCCYVSCQECTRVYDVHTCK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P27467-1", "uniprot_id": "WNT3A_MOUSE", "id": "P27467-1", "name": "Protein Wnt-3a", "aln": "MAPLGYLLVL-CSLKQALGSYPIWWSLAVGPQYSSLSTQPILCASIPGLVPKQLRFCRNYVEIMPSVAEGVKAGIQECQHQFRGRRWNCTTVSNSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGSAAICGCSSRLQGSPGEGWKWGGCSEDIEFGGMVSREFADARENRPDARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRTIGDFLKDKYDSASEMVVEKHRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNARTERRREKCHCVFHWCCYVSCQECTRVYDVHTCK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56704-1", "uniprot_id": "WNT3A_HUMAN", "id": "P56704-1", "name": "Protein Wnt-3a", "aln": "MAPLGYFLLL-CSLKQALGSYPIWWSLAVGPQYSSLGSQPILCASIPGLVPKQLRFCRNYVEIMPSVAEGIKIGIQECQHQFRGRRWNCTTVHDSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTAAICGCSSRHQGSPGKGWKWGGCSEDIEFGGMVSREFADARENRPDARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNARAERRREKCRCVFHWCCYVSCQECTRVYDVHTCK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BB70-1", "uniprot_id": "A0A8M2BB70_DANRE", "id": "A0A8M2BB70-1", "name": "Protein Wnt", "aln": "MIYLGYFLFLFCGLTRVMASYPIWWSLAVGHQYTSLGTQPIMCSSIPGLVPKQLRFCRNYVEIMPSVAEGVKIGIQECQHQFRGRRWNCTTINDKLAIFGPVLDKATRESAFVHAIASAGVAFAVTRACAEGSATICGCDSRRKGPPGEGWKWGGCSEDVEFGSMVSREFADARENRPDARSAMNRHNNEAGRSSITDHMYLKCKCHGLSGSCEVKTCWWSQPDFRVIGDYMKDKYDSASEMVVEKHRESRGWVETLRPKYPYYKPPTETDLVYYESSPNFCEPNPETGSFGTRDRTCNLTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCIFHWCCYVSCQECTRVYDVHTCK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ***:*.* *.*.:.:.*********** **:**.:***:*:**************************:* ******************: :.********************************:****:*:****.** :*.**:**********:***.*****************************.:*:.**:*************************.***::***************************:*.*:* *** ******:**********************::*****************:*:*:*:***:*:**********************", "identical_positions": 298, "similar_positions": 46, "identity": "84.42%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001106-11", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LWD2-1", "uniprot_id": "A0ABK0LWD2_RAT", "id": "A0ABK0LWD2-1", "name": "Ig-like domain-containing protein", "aln": "MGMLL-QVLVGLLMFPAVWVNT-QKLQQSPQSLTIQEGDELTMSCNSS--SSLYALHWYRQGRDGGPIFLVTLQKGGDEKRKD-----KITAKLDKKMRQSFLSIQASQPSYAGTYLCAGSAQWSIDCRGLSPNLQLGHSCSDTGPLRQD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A075B657-1", "uniprot_id": "A0A075B657_MOUSE", "id": "A0A075B657-1", "name": "", "aln": "MGMRL-QVLAWLLTFQAAWVNT-QMLHQSPQSLTIQEGDEVTMSCNLS--TSLYALLWYRQGDDGSLVSLVTLQKGGDEKSKD-----KITANLDKKMQQSSLWIQASQPSHSGTYLCGGK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J273-1", "uniprot_id": "TVA34_HUMAN", "id": "A0A0B4J273-1", "name": "T cell receptor alpha variable 34", "aln": "METVL-QVLLGILGFQAAWVSS-QELEQSPQSLIVQEGKNLTINCTSS--KTLYGLYWYKQKYGEGLIFLMMLQKGGEEKSHE-----KITAKLDEKKQQSSLHITASQPSHAGIYLCGAD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5R1B6-1", "uniprot_id": "Q5R1B6_MOUSE", "id": "Q5R1B6-1", "name": "", "aln": "MNRFL-GISLVTLWFRVAWAKS-QWGEENLQALSIQEGEDVTMNCSYK--TYTTVVHWYRQDSGRGPALIILIRSNEREKRSG-----RLRATLDTSSQSSSLSITAAQCEDTAVYFCATD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B633-1", "uniprot_id": "A0A075B633_MOUSE", "id": "A0A075B633-1", "name": "", "aln": "MNRFL-GISLVTLWFQVAWAKS-QWGEENLQALSIQEGEDVTMNCSYK--TYTTVVQWYRQKSGKGPAQLILIRSNEREKRSG-----RLRATLDTSSQSSSLSITGTLATDTAVYFCATD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B641-1", "uniprot_id": "A0A075B641_MOUSE", "id": "A0A075B641-1", "name": "", "aln": "MHSLL-GLL---LWLQLTRVNS-QLAEENSWALSVHEGESVTVNCSYK--TSITALQWYRQKSGKGPAQLILIRSNEREKRNG-----RLRATLDTSSQSSSLSITATRCEDTAVYFCATD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5R1H8-1", "uniprot_id": "Q5R1H8_MOUSE", "id": "Q5R1H8-1", "name": "", "aln": "MHSLL-GLLMVSLWLQLTRVNS-QLAEENLWALSVHEGESVTVNCSYK--TSITALQWYRQKSGEGPAQLILIRSNEREKRNG-----RLRATLDTSSQSSSLSITATRCEDTAVYFCATD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J275-1", "uniprot_id": "TVA17_HUMAN", "id": "A0A0B4J275-1", "name": "T cell receptor alpha variable 17", "aln": "METLL-GVSLVILWLQLARVNS-QQGEEDPQALSIQEGENATMNCSYK--TSINNLQWYRQNSGRGLVHLILIRSNEREKHSG-----RLRVTLDTSKKSSSLLITASRAADTASYFCATD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J279-1", "uniprot_id": "TVA21_HUMAN", "id": "A0A0B4J279-1", "name": "T cell receptor alpha variable 21", "aln": "METLL-GLLI--LWLQLQWVSSKQEVTQIPAALSVPEGENLVLNCSFTD-SAIYNLQWFRQDPGKGLTSLLLIQSSQREQTSG-----RLNASLDKSSGRSTLYIAASQPGDSATYLCAVR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B6U4-1", "uniprot_id": "TVA7_HUMAN", "id": "A0A075B6U4-1", "name": "T cell receptor alpha variable 7", "aln": "MEKMR-RPVLIIFCLCLGWANGENQVEHSPHFLGPQQGDVASMSCTYSV-SRFNNLQWYRQNTGMGPKHLLSMYSAGYEKQKG-----RLNATLLKNG--SSLYITAVQPEDSATYFCAVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J274-1", "uniprot_id": "TVA20_HUMAN", "id": "A0A0B4J274-1", "name": "T cell receptor alpha variable 20", "aln": "MEKML-ECAFIVLWLQLGWLSGEDQVTQSPEALRLQEGESSSLNCSYTV-SGLRGLFWYRQDPGKGPEFLFTLYSAGEEKEKE-----RLKATLTKKE--SFLHITAPKPEDSATYLCAVQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B6V5-1", "uniprot_id": "TVA36_HUMAN", "id": "A0A075B6V5-1", "name": "T cell receptor alpha variable 36/delta variable 7", "aln": "MMKCP-QALLAIFWLLLSWVSSEDKVVQSPLSLVVHEGDTVTLNCSYEV-TNFRSLLWYKQE-KKAPTFLFMLTSSGIEKKSG-----RLSSILDKKELFSILNITATQTGDSAIYLCAVE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J272-1", "uniprot_id": "TVA24_HUMAN", "id": "A0A0B4J272-1", "name": "T cell receptor alpha variable 24", "aln": "MEKNPLAAPLLILWFHLDCVSSILNVEQSPQSLHVQEGDSTNFTCSFPS-SNFYALHWYRWETAKSPEALFVMTLNGDEKKKG-----RISATLNTKEGYSYLYIKGSQPEDSATYLCAF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J1J9-1", "uniprot_id": "A0A0B4J1J9_MOUSE", "id": "A0A0B4J1J9-1", "name": "", "aln": "MKKRL-SACWVVLWLHYQWVAGKTQVEQSPQSLVVRQGENCVLQCNYSV-TPDNHLRWFKQDTGKGLVSLTVLVDQKDKTSNG-----RYSATLDKDAKHSTLHITATLLDDTATYICVVG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J240-1", "uniprot_id": "TVA10_HUMAN", "id": "A0A0B4J240-1", "name": "T cell receptor alpha variable 10", "aln": "MKKHL-TTFLVILWLYFYRGNGKNQVEQSPQSLIILEGKNCTLQCNYTV-SPFSNLRWYKQDTGRGPVSLTIMTFSENTKSNG-----RYTATLDADTKQSSLHITASQLSDSASYICVVS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B642-1", "uniprot_id": "A0A075B642_MOUSE", "id": "A0A075B642-1", "name": "", "aln": "-MKTSLHTVFLFLWLWMDWESHGEKVEQHESTLSVREGDSAVINCTYTD-TASSYFPWYKQEAGKSLHFVIDIRSNVDRKQSQ-----RLIVLLDKKAKRFSLHITATQPEDSAIYFCAAS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B622-1", "uniprot_id": "A0A075B622_MOUSE", "id": "A0A075B622-1", "name": "", "aln": "-MKTSLHTVFLFLWLWMDWESHGEKVEQHESTLSVREGDSAVINCTYTD-TASSYFPWYKQEAGKSLHFVIDIRSNVDRKQSQ-----RLTVLLDKKAKRFSLHITATQPEDSAIYFCAAS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5R1F6-1", "uniprot_id": "Q5R1F6_MOUSE", "id": "Q5R1F6-1", "name": "", "aln": "-MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYEN-SASNYFPWYKQEPGENPKLIIDIRSNMERKQTQ-----GLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B652-1", "uniprot_id": "A0A075B652_MOUSE", "id": "A0A075B652-1", "name": "", "aln": "-MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCSYED-SASNYFPWYKQEPGENPKLIIDIRSNMERKQIQ-----ELIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B5Z7-1", "uniprot_id": "A0A075B5Z7_MOUSE", "id": "A0A075B5Z7-1", "name": "", "aln": "-MKTAIHALFIFFWLQMDWKSQGEQVEQLPSSLIVQEGASVLINCSYTD-SASVYFPWYKQEPGKRLQFIIDIRSNMERKQTQ-----RLTLLFDKKTKHLSLHITATQPGDSAIYFCSAS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J249-1", "uniprot_id": "TVA5_HUMAN", "id": "A0A0B4J249-1", "name": "T cell receptor alpha variable 5", "aln": "-MKTFAGFSFLFLWLQLDCMSRGEDVEQS-LFLSVREGDSSVINCTYTD-SSSTYLYWYKQEPGAGLQLLTYIFSNMDMKQDQ-----RLTVLLNKKDKHLSLRIADTQTGDSAIYFCAES---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J241-1", "uniprot_id": "TVAM1_HUMAN", "id": "A0A0B4J241-1", "name": "T cell receptor alpha variable 13-1", "aln": "--MTSIRAVFIFLWLQLDLVN-GENVEQHPSTLSVQEGDSAVIKCTYSD-SASNYFPWYKQELGKGPQLIIDIRSNVGEKKDQ-----RIAVTLNKTAKHFSLHITETQPEDSAVYFCAAS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J235-1", "uniprot_id": "TVAM2_HUMAN", "id": "A0A0B4J235-1", "name": "T cell receptor alpha variable 13-2", "aln": "--MAGIRALFMYLWLQLDWVSRGESVGLHLPTLSVQEGDNSIINCAYSN-SASDYFIWYKQESGKGPQFIIDIRSNMDKRQGQ-----RVTVLLNKTVKHLSLQIAATQPGDSAVYFCAEN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B614-1", "uniprot_id": "A0A075B614_MOUSE", "id": "A0A075B614-1", "name": "", "aln": "----------------------GEQVEQRPPHLSVREGDSAVIICTYTD-PNSYYFFWYKQEPGAGLQLLMKVFSSTEINEGQ-----GFTVLLNKKDKQLSLNLTAAHPGDSAVYFCAV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B5Z4-1", "uniprot_id": "A0A075B5Z4_MOUSE", "id": "A0A075B5Z4-1", "name": "", "aln": "----MLQMWGFVLYLFLTVGGAAGQGVEQPAKLMSVEGTFARVNCTYST-SGFNGLSWYQQREGQAPVFLSYVVLDG-LKDSG-----HFSTFLSRSNGYSYLLLTELQIKDSASYLCAVR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5R1I9-1", "uniprot_id": "Q5R1I9_MOUSE", "id": "Q5R1I9-1", "name": "", "aln": "------MKQVAKVTVLLILVSWSLAKTTQPPSMEAYEGQEVNVSCSHTNIATSEYIYWYRQVPHQGPQFIIQGYKDYVVNEVA-----SLFISADRKL--STLSLPWVSLRDAAVYYCIVTD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B6C4-1", "uniprot_id": "A0A075B6C4_MOUSE", "id": "A0A075B6C4-1", "name": "", "aln": "------MGCVSGIAILLALGIAGDAKTTQPDSMESTEGETVHLPCSHATISGNEYIYWYRQVPLQGPEYVTHGLQQNTTNSMA-----FLAIASDRKS--STLILPHVSLRDAAVYHCILRV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PDP1-1", "uniprot_id": "A0A8M1PDP1_DANRE", "id": "A0A8M1PDP1-1", "name": "", "aln": "--MNHIIYVIIFLFHPQVSGKNNCTVDQVDEVLTTQEGHIVLLPCLLLE-DHFHRVIWYKQVLGEKPVVIVSSYHHSQPNEFSSDFKETQRFHAVRKADSFNLTIRRTLKSDSGTYFCGSAFANVVSFGTGTILLVKGADLKPAVIQHPVHAFIKPESNVTLRCSVEGKTCDKGVQSVYWFRQSLNTTHQGIVYTHGKSKNECADSSDTQSCLQNLAKMSVDVSEAGLYYCSVVTCDEVLFGNGTTLVIKDGFISESIQKCILIGLTVLSAVSLTINILLSLPLRRNGGKPQQMQTNDDITRVQFQNADDVNYAALNLSSKRGQRKMTLEKTPTQTNAAR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* . * . *:: : * : :. * * ", "identical_positions": 6, "similar_positions": 10, "identity": "1.76%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001106-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A075B5Z4-1", "uniprot_id": "A0A075B5Z4_MOUSE", "id": "A0A075B5Z4-1", "name": "", "aln": "--------------MLQMWGFVLYLFLTVGGAAGQGVEQPAKLMSVEGTFARVNCTYST-SGFNGLSWYQQREGQAPVFLSYVVLDG-LKDSGHFSTF----LSRSNGYSYLLLTELQIKDSASYLCAVR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LWD2-1", "uniprot_id": "A0ABK0LWD2_RAT", "id": "A0ABK0LWD2-1", "name": "Ig-like domain-containing protein", "aln": "----------MGMLL-QVLVGLLMFPAVWVNT-QKLQQSPQSLTIQEGDELTMSCNSS--SSLYALHWYRQGRDGGPIFLVTLQKGGDEKRKDKITAK----LDKKMRQSFLSIQASQPSYAGTYLCAGSAQWSIDCRGLSPNLQLGHSCSDTGPLRQD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A075B657-1", "uniprot_id": "A0A075B657_MOUSE", "id": "A0A075B657-1", "name": "", "aln": "----------MGMRL-QVLAWLLTFQAAWVNT-QMLHQSPQSLTIQEGDEVTMSCNLS--TSLYALLWYRQGDDGSLVSLVTLQKGGDEKSKDKITAN----LDKKMQQSSLWIQASQPSHSGTYLCGGK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J273-1", "uniprot_id": "TVA34_HUMAN", "id": "A0A0B4J273-1", "name": "T cell receptor alpha variable 34", "aln": "----------METVL-QVLLGILGFQAAWVSS-QELEQSPQSLIVQEGKNLTINCTSS--KTLYGLYWYKQKYGEGLIFLMMLQKGGEEKSHEKITAK----LDEKKQQSSLHITASQPSHAGIYLCGAD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5R1B6-1", "uniprot_id": "Q5R1B6_MOUSE", "id": "Q5R1B6-1", "name": "", "aln": "----------MNRFL-GISLVTLWFRVAWAKS-QWGEENLQALSIQEGEDVTMNCSYK--TYTTVVHWYRQDSGRGPALIILIRSNEREKRSGRLRAT----LDTSSQSSSLSITAAQCEDTAVYFCATD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B633-1", "uniprot_id": "A0A075B633_MOUSE", "id": "A0A075B633-1", "name": "", "aln": "----------MNRFL-GISLVTLWFQVAWAKS-QWGEENLQALSIQEGEDVTMNCSYK--TYTTVVQWYRQKSGKGPAQLILIRSNEREKRSGRLRAT----LDTSSQSSSLSITGTLATDTAVYFCATD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B641-1", "uniprot_id": "A0A075B641_MOUSE", "id": "A0A075B641-1", "name": "", "aln": "----------MHSLL-GLL---LWLQLTRVNS-QLAEENSWALSVHEGESVTVNCSYK--TSITALQWYRQKSGKGPAQLILIRSNEREKRNGRLRAT----LDTSSQSSSLSITATRCEDTAVYFCATD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5R1H8-1", "uniprot_id": "Q5R1H8_MOUSE", "id": "Q5R1H8-1", "name": "", "aln": "----------MHSLL-GLLMVSLWLQLTRVNS-QLAEENLWALSVHEGESVTVNCSYK--TSITALQWYRQKSGEGPAQLILIRSNEREKRNGRLRAT----LDTSSQSSSLSITATRCEDTAVYFCATD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J275-1", "uniprot_id": "TVA17_HUMAN", "id": "A0A0B4J275-1", "name": "T cell receptor alpha variable 17", "aln": "----------METLL-GVSLVILWLQLARVNS-QQGEEDPQALSIQEGENATMNCSYK--TSINNLQWYRQNSGRGLVHLILIRSNEREKHSGRLRVT----LDTSKKSSSLLITASRAADTASYFCATD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J279-1", "uniprot_id": "TVA21_HUMAN", "id": "A0A0B4J279-1", "name": "T cell receptor alpha variable 21", "aln": "----------METLL-GLLI--LWLQLQWVSSKQEVTQIPAALSVPEGENLVLNCSFTD-SAIYNLQWFRQDPGKGLTSLLLIQSSQREQTSGRLNAS----LDKSSGRSTLYIAASQPGDSATYLCAVR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B6U4-1", "uniprot_id": "TVA7_HUMAN", "id": "A0A075B6U4-1", "name": "T cell receptor alpha variable 7", "aln": "----------MEKMR-RPVLIIFCLCLGWANGENQVEHSPHFLGPQQGDVASMSCTYSV-SRFNNLQWYRQNTGMGPKHLLSMYSAGYEKQKGRLNAT----LLKNG--SSLYITAVQPEDSATYFCAVD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J274-1", "uniprot_id": "TVA20_HUMAN", "id": "A0A0B4J274-1", "name": "T cell receptor alpha variable 20", "aln": "----------MEKML-ECAFIVLWLQLGWLSGEDQVTQSPEALRLQEGESSSLNCSYTV-SGLRGLFWYRQDPGKGPEFLFTLYSAGEEKEKERLKAT----LTKKE--SFLHITAPKPEDSATYLCAVQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B6V5-1", "uniprot_id": "TVA36_HUMAN", "id": "A0A075B6V5-1", "name": "T cell receptor alpha variable 36/delta variable 7", "aln": "----------MMKCP-QALLAIFWLLLSWVSSEDKVVQSPLSLVVHEGDTVTLNCSYEV-TNFRSLLWYKQE-KKAPTFLFMLTSSGIEKKSGRLSSI----LDKKELFSILNITATQTGDSAIYLCAVE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J272-1", "uniprot_id": "TVA24_HUMAN", "id": "A0A0B4J272-1", "name": "T cell receptor alpha variable 24", "aln": "----------MEKNPLAAPLLILWFHLDCVSSILNVEQSPQSLHVQEGDSTNFTCSFPS-SNFYALHWYRWETAKSPEALFVMTLNGDEKKKGRISAT----LNTKEGYSYLYIKGSQPEDSATYLCAF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J1J9-1", "uniprot_id": "A0A0B4J1J9_MOUSE", "id": "A0A0B4J1J9-1", "name": "", "aln": "----------MKKRL-SACWVVLWLHYQWVAGKTQVEQSPQSLVVRQGENCVLQCNYSV-TPDNHLRWFKQDTGKGLVSLTVLVDQKDKTSNGRYSAT----LDKDAKHSTLHITATLLDDTATYICVVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J240-1", "uniprot_id": "TVA10_HUMAN", "id": "A0A0B4J240-1", "name": "T cell receptor alpha variable 10", "aln": "----------MKKHL-TTFLVILWLYFYRGNGKNQVEQSPQSLIILEGKNCTLQCNYTV-SPFSNLRWYKQDTGRGPVSLTIMTFSENTKSNGRYTAT----LDADTKQSSLHITASQLSDSASYICVVS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B642-1", "uniprot_id": "A0A075B642_MOUSE", "id": "A0A075B642-1", "name": "", "aln": "-----------MKTSLHTVFLFLWLWMDWESHGEKVEQHESTLSVREGDSAVINCTYTD-TASSYFPWYKQEAGKSLHFVIDIRSNVDRKQSQRLIVL----LDKKAKRFSLHITATQPEDSAIYFCAAS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B622-1", "uniprot_id": "A0A075B622_MOUSE", "id": "A0A075B622-1", "name": "", "aln": "-----------MKTSLHTVFLFLWLWMDWESHGEKVEQHESTLSVREGDSAVINCTYTD-TASSYFPWYKQEAGKSLHFVIDIRSNVDRKQSQRLTVL----LDKKAKRFSLHITATQPEDSAIYFCAAS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5R1F6-1", "uniprot_id": "Q5R1F6_MOUSE", "id": "Q5R1F6-1", "name": "", "aln": "-----------MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYEN-SASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVL----LDKKAKRFSLHITDTQPGDSAMYFCAAS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B652-1", "uniprot_id": "A0A075B652_MOUSE", "id": "A0A075B652-1", "name": "", "aln": "-----------MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCSYED-SASNYFPWYKQEPGENPKLIIDIRSNMERKQIQELIVL----LDKKAKRFSLHITDTQPGDSAMYFCAAS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B5Z7-1", "uniprot_id": "A0A075B5Z7_MOUSE", "id": "A0A075B5Z7-1", "name": "", "aln": "-----------MKTAIHALFIFFWLQMDWKSQGEQVEQLPSSLIVQEGASVLINCSYTD-SASVYFPWYKQEPGKRLQFIIDIRSNMERKQTQRLTLL----FDKKTKHLSLHITATQPGDSAIYFCSAS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J249-1", "uniprot_id": "TVA5_HUMAN", "id": "A0A0B4J249-1", "name": "T cell receptor alpha variable 5", "aln": "-----------MKTFAGFSFLFLWLQLDCMSRGEDVEQS-LFLSVREGDSSVINCTYTD-SSSTYLYWYKQEPGAGLQLLTYIFSNMDMKQDQRLTVL----LNKKDKHLSLRIADTQTGDSAIYFCAES----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J241-1", "uniprot_id": "TVAM1_HUMAN", "id": "A0A0B4J241-1", "name": "T cell receptor alpha variable 13-1", "aln": "------------MTSIRAVFIFLWLQLDLVN-GENVEQHPSTLSVQEGDSAVIKCTYSD-SASNYFPWYKQELGKGPQLIIDIRSNVGEKKDQRIAVT----LNKTAKHFSLHITETQPEDSAVYFCAAS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J235-1", "uniprot_id": "TVAM2_HUMAN", "id": "A0A0B4J235-1", "name": "T cell receptor alpha variable 13-2", "aln": "------------MAGIRALFMYLWLQLDWVSRGESVGLHLPTLSVQEGDNSIINCAYSN-SASDYFIWYKQESGKGPQFIIDIRSNMDKRQGQRVTVL----LNKTVKHLSLQIAATQPGDSAVYFCAEN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B614-1", "uniprot_id": "A0A075B614_MOUSE", "id": "A0A075B614-1", "name": "", "aln": "--------------------------------GEQVEQRPPHLSVREGDSAVIICTYTD-PNSYYFFWYKQEPGAGLQLLMKVFSSTEINEGQGFTVL----LNKKDKQLSLNLTAAHPGDSAVYFCAV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5R1I9-1", "uniprot_id": "Q5R1I9_MOUSE", "id": "Q5R1I9-1", "name": "", "aln": "----------------MKQVAKVTVLLILVSWSLAKTTQPPSMEAYEGQEVNVSCSHTNIATSEYIYWYRQVPHQGPQFIIQGYKDYVVNEVASLFIS----ADRKL--STLSLPWVSLRDAAVYYCIVTD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B6C4-1", "uniprot_id": "A0A075B6C4_MOUSE", "id": "A0A075B6C4-1", "name": "", "aln": "----------------MGCVSGIAILLALGIAGDAKTTQPDSMESTEGETVHLPCSHATISGNEYIYWYRQVPLQGPEYVTHGLQQNTTNSMAFLAIA----SDRKS--STLILPHVSLRDAAVYHCILRV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58G0B8-1", "uniprot_id": "A0AC58G0B8_DANRE", "id": "A0AC58G0B8-1", "name": "", "aln": "MGNSKHKDHFEGRLIMRYYFIVLLSSTIFCSTGFDVVQEDTVKIVEAGGDVNFTCIFPG-HVPSTKAWFKQTTVGKYLQIVSLDLKKQLKWNSSFEKTNRFNVTKVDDYFNLTILKTKPSDSATYYCVVSAYETIGMGSATRLLVKDAAADRNTTLHQSLIETVDPGDSVNLQCSIFTESCAGDHSVYWFKQSSGHPEGVLYTKGERNGRCKNNTESQTQSCVYSLHKNNISRSDSGIYYCAVDQCGEILFGRGTQLNIREYFDFNPGLLALGISNIMFLALVVVLGIKLCRSQIKTSASQTTQDEDGLNYASITFRQKPLNTRRARAKFTQDQSLYAQVRSHQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * *:: : * : :. * * ", "identical_positions": 6, "similar_positions": 7, "identity": "1.74%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001106-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LWD2-1", "uniprot_id": "A0ABK0LWD2_RAT", "id": "A0ABK0LWD2-1", "name": "Ig-like domain-containing protein", "aln": "----------MGMLL-QVLVGLLMFPAVWVNT-QKLQQSPQSLTIQEGDELTMSCNSS--SSLYALHWYRQGRDGGPIFLVTLQKGGDEKRKDKIT----AKLDKKMRQSFLSIQASQPSYAGTYLCAGSAQWSIDCRGLSPNLQLGHSCSDTGPLRQD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A075B657-1", "uniprot_id": "A0A075B657_MOUSE", "id": "A0A075B657-1", "name": "", "aln": "----------MGMRL-QVLAWLLTFQAAWVNT-QMLHQSPQSLTIQEGDEVTMSCNLS--TSLYALLWYRQGDDGSLVSLVTLQKGGDEKSKDKIT----ANLDKKMQQSSLWIQASQPSHSGTYLCGGK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J273-1", "uniprot_id": "TVA34_HUMAN", "id": "A0A0B4J273-1", "name": "T cell receptor alpha variable 34", "aln": "----------METVL-QVLLGILGFQAAWVSS-QELEQSPQSLIVQEGKNLTINCTSS--KTLYGLYWYKQKYGEGLIFLMMLQKGGEEKSHEKIT----AKLDEKKQQSSLHITASQPSHAGIYLCGAD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5R1B6-1", "uniprot_id": "Q5R1B6_MOUSE", "id": "Q5R1B6-1", "name": "", "aln": "----------MNRFL-GISLVTLWFRVAWAKS-QWGEENLQALSIQEGEDVTMNCSYK--TYTTVVHWYRQDSGRGPALIILIRSNEREKRSGRLR----ATLDTSSQSSSLSITAAQCEDTAVYFCATD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B633-1", "uniprot_id": "A0A075B633_MOUSE", "id": "A0A075B633-1", "name": "", "aln": "----------MNRFL-GISLVTLWFQVAWAKS-QWGEENLQALSIQEGEDVTMNCSYK--TYTTVVQWYRQKSGKGPAQLILIRSNEREKRSGRLR----ATLDTSSQSSSLSITGTLATDTAVYFCATD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B641-1", "uniprot_id": "A0A075B641_MOUSE", "id": "A0A075B641-1", "name": "", "aln": "----------MHSLL-GLL---LWLQLTRVNS-QLAEENSWALSVHEGESVTVNCSYK--TSITALQWYRQKSGKGPAQLILIRSNEREKRNGRLR----ATLDTSSQSSSLSITATRCEDTAVYFCATD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5R1H8-1", "uniprot_id": "Q5R1H8_MOUSE", "id": "Q5R1H8-1", "name": "", "aln": "----------MHSLL-GLLMVSLWLQLTRVNS-QLAEENLWALSVHEGESVTVNCSYK--TSITALQWYRQKSGEGPAQLILIRSNEREKRNGRLR----ATLDTSSQSSSLSITATRCEDTAVYFCATD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J275-1", "uniprot_id": "TVA17_HUMAN", "id": "A0A0B4J275-1", "name": "T cell receptor alpha variable 17", "aln": "----------METLL-GVSLVILWLQLARVNS-QQGEEDPQALSIQEGENATMNCSYK--TSINNLQWYRQNSGRGLVHLILIRSNEREKHSGRLR----VTLDTSKKSSSLLITASRAADTASYFCATD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J279-1", "uniprot_id": "TVA21_HUMAN", "id": "A0A0B4J279-1", "name": "T cell receptor alpha variable 21", "aln": "----------METLL-GLLI--LWLQLQWVSSKQEVTQIPAALSVPEGENLVLNCSFTD-SAIYNLQWFRQDPGKGLTSLLLIQSSQREQTSGRLN----ASLDKSSGRSTLYIAASQPGDSATYLCAVR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J1J9-1", "uniprot_id": "A0A0B4J1J9_MOUSE", "id": "A0A0B4J1J9-1", "name": "", "aln": "----------MKKRL-SACWVVLWLHYQWVAGKTQVEQSPQSLVVRQGENCVLQCNYSV-TPDNHLRWFKQDTGKGLVSLTVLVDQKDKTSNGRYS----ATLDKDAKHSTLHITATLLDDTATYICVVG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J240-1", "uniprot_id": "TVA10_HUMAN", "id": "A0A0B4J240-1", "name": "T cell receptor alpha variable 10", "aln": "----------MKKHL-TTFLVILWLYFYRGNGKNQVEQSPQSLIILEGKNCTLQCNYTV-SPFSNLRWYKQDTGRGPVSLTIMTFSENTKSNGRYT----ATLDADTKQSSLHITASQLSDSASYICVVS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B6U4-1", "uniprot_id": "TVA7_HUMAN", "id": "A0A075B6U4-1", "name": "T cell receptor alpha variable 7", "aln": "----------MEKMR-RPVLIIFCLCLGWANGENQVEHSPHFLGPQQGDVASMSCTYSV-SRFNNLQWYRQNTGMGPKHLLSMYSAGYEKQKGRLN----ATLLKNG--SSLYITAVQPEDSATYFCAVD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J274-1", "uniprot_id": "TVA20_HUMAN", "id": "A0A0B4J274-1", "name": "T cell receptor alpha variable 20", "aln": "----------MEKML-ECAFIVLWLQLGWLSGEDQVTQSPEALRLQEGESSSLNCSYTV-SGLRGLFWYRQDPGKGPEFLFTLYSAGEEKEKERLK----ATLTKKE--SFLHITAPKPEDSATYLCAVQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B6V5-1", "uniprot_id": "TVA36_HUMAN", "id": "A0A075B6V5-1", "name": "T cell receptor alpha variable 36/delta variable 7", "aln": "----------MMKCP-QALLAIFWLLLSWVSSEDKVVQSPLSLVVHEGDTVTLNCSYEV-TNFRSLLWYKQE-KKAPTFLFMLTSSGIEKKSGRLS----SILDKKELFSILNITATQTGDSAIYLCAVE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J272-1", "uniprot_id": "TVA24_HUMAN", "id": "A0A0B4J272-1", "name": "T cell receptor alpha variable 24", "aln": "----------MEKNPLAAPLLILWFHLDCVSSILNVEQSPQSLHVQEGDSTNFTCSFPS-SNFYALHWYRWETAKSPEALFVMTLNGDEKKKGRIS----ATLNTKEGYSYLYIKGSQPEDSATYLCAF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B642-1", "uniprot_id": "A0A075B642_MOUSE", "id": "A0A075B642-1", "name": "", "aln": "-----------MKTSLHTVFLFLWLWMDWESHGEKVEQHESTLSVREGDSAVINCTYTD-TASSYFPWYKQEAGKSLHFVIDIRSNVDRKQSQRLI----VLLDKKAKRFSLHITATQPEDSAIYFCAAS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B622-1", "uniprot_id": "A0A075B622_MOUSE", "id": "A0A075B622-1", "name": "", "aln": "-----------MKTSLHTVFLFLWLWMDWESHGEKVEQHESTLSVREGDSAVINCTYTD-TASSYFPWYKQEAGKSLHFVIDIRSNVDRKQSQRLT----VLLDKKAKRFSLHITATQPEDSAIYFCAAS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5R1F6-1", "uniprot_id": "Q5R1F6_MOUSE", "id": "Q5R1F6-1", "name": "", "aln": "-----------MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYEN-SASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLI----VLLDKKAKRFSLHITDTQPGDSAMYFCAAS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B652-1", "uniprot_id": "A0A075B652_MOUSE", "id": "A0A075B652-1", "name": "", "aln": "-----------MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCSYED-SASNYFPWYKQEPGENPKLIIDIRSNMERKQIQELI----VLLDKKAKRFSLHITDTQPGDSAMYFCAAS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B5Z7-1", "uniprot_id": "A0A075B5Z7_MOUSE", "id": "A0A075B5Z7-1", "name": "", "aln": "-----------MKTAIHALFIFFWLQMDWKSQGEQVEQLPSSLIVQEGASVLINCSYTD-SASVYFPWYKQEPGKRLQFIIDIRSNMERKQTQRLT----LLFDKKTKHLSLHITATQPGDSAIYFCSAS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J249-1", "uniprot_id": "TVA5_HUMAN", "id": "A0A0B4J249-1", "name": "T cell receptor alpha variable 5", "aln": "-----------MKTFAGFSFLFLWLQLDCMSRGEDVEQS-LFLSVREGDSSVINCTYTD-SSSTYLYWYKQEPGAGLQLLTYIFSNMDMKQDQRLT----VLLNKKDKHLSLRIADTQTGDSAIYFCAES------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J241-1", "uniprot_id": "TVAM1_HUMAN", "id": "A0A0B4J241-1", "name": "T cell receptor alpha variable 13-1", "aln": "------------MTSIRAVFIFLWLQLDLVN-GENVEQHPSTLSVQEGDSAVIKCTYSD-SASNYFPWYKQELGKGPQLIIDIRSNVGEKKDQRIA----VTLNKTAKHFSLHITETQPEDSAVYFCAAS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J235-1", "uniprot_id": "TVAM2_HUMAN", "id": "A0A0B4J235-1", "name": "T cell receptor alpha variable 13-2", "aln": "------------MAGIRALFMYLWLQLDWVSRGESVGLHLPTLSVQEGDNSIINCAYSN-SASDYFIWYKQESGKGPQFIIDIRSNMDKRQGQRVT----VLLNKTVKHLSLQIAATQPGDSAVYFCAEN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B614-1", "uniprot_id": "A0A075B614_MOUSE", "id": "A0A075B614-1", "name": "", "aln": "--------------------------------GEQVEQRPPHLSVREGDSAVIICTYTD-PNSYYFFWYKQEPGAGLQLLMKVFSSTEINEGQGFT----VLLNKKDKQLSLNLTAAHPGDSAVYFCAV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B5Z4-1", "uniprot_id": "A0A075B5Z4_MOUSE", "id": "A0A075B5Z4-1", "name": "", "aln": "--------------MLQMWGFVLYLFLTVGGAAGQGVEQPAKLMSVEGTFARVNCTYST-SGFNGLSWYQQREGQAPVFLSYVVLDG-LKDSGHFS----TFLSRSNGYSYLLLTELQIKDSASYLCAVR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5R1I9-1", "uniprot_id": "Q5R1I9_MOUSE", "id": "Q5R1I9-1", "name": "", "aln": "----------------MKQVAKVTVLLILVSWSLAKTTQPPSMEAYEGQEVNVSCSHTNIATSEYIYWYRQVPHQGPQFIIQGYKDYVVNEVASLF----ISADRKL--STLSLPWVSLRDAAVYYCIVTD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B6C4-1", "uniprot_id": "A0A075B6C4_MOUSE", "id": "A0A075B6C4-1", "name": "", "aln": "----------------MGCVSGIAILLALGIAGDAKTTQPDSMESTEGETVHLPCSHATISGNEYIYWYRQVPLQGPEYVTHGLQQNTTNSMAFLA----IASDRKS--STLILPHVSLRDAAVYHCILRV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58G3K4-1", "uniprot_id": "A0AC58G3K4_DANRE", "id": "A0AC58G3K4-1", "name": "", "aln": "MSKSESADFYQSFKMIHCFFILLLYLLTCTSDNANKQGQNHVKIIQAGDAVNLTCIFPK-ESRTSVVWVKQRVGEKPLLIASAYQGLAGKYENDFDKQNRFFIEKDEGSFNLSIANTEISDTATYYCVAYVYEFIFGNSTDLIVNAGELNIKSEHQRSESEDLQCSVISQSCAEEHKVYWFRQRSGESPPGVIYTQNNRSAQCEKSSDRNSAAHKCIYSLPKTDEDPAIYYCAVVACGQILFGDVVTIPGFWTLWKTVALALAISNSLLMIVIIFLGMRFYKFQKNDRTQNIQLGQLMDEDRGVLNYAALSFQQKSSTSRRPKEKHLR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * . * : : * : :. * * ", "identical_positions": 6, "similar_positions": 7, "identity": "1.83%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001106-8", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LWD2-1", "uniprot_id": "A0ABK0LWD2_RAT", "id": "A0ABK0LWD2-1", "name": "Ig-like domain-containing protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MGMLLQVLVGLLMFPAVWVNTQ-KLQQSPQSLTIQEGDELTMSCNSSSS----LYALHWYRQGRDGGPIFLVTLQKGGDEKRKDKITAKLDKKMRQSFLSIQASQPSYAGTYLCAGSAQWSIDCRGLSPNLQLGHSCSDTGPLRQD------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A075B657-1", "uniprot_id": "A0A075B657_MOUSE", "id": "A0A075B657-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MGMRLQVLAWLLTFQAAWVNTQ-MLHQSPQSLTIQEGDEVTMSCNLSTS----LYALLWYRQGDDGSLVSLVTLQKGGDEKSKDKITANLDKKMQQSSLWIQASQPSHSGTYLCGGK-----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J273-1", "uniprot_id": "TVA34_HUMAN", "id": "A0A0B4J273-1", "name": "T cell receptor alpha variable 34", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------METVLQVLLGILGFQAAWVSSQ-ELEQSPQSLIVQEGKNLTINCTSSKT----LYGLYWYKQKYGEGLIFLMMLQKGGEEKSHEKITAKLDEKKQQSSLHITASQPSHAGIYLCGAD-----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J1J9-1", "uniprot_id": "A0A0B4J1J9_MOUSE", "id": "A0A0B4J1J9-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MKKRL-SACWVVLWLHYQWVAGKTQVEQSPQSLVVRQGENCVLQCNYSVTP---DNHLRWFKQDTGKGLVSLTVLVDQKDKTSNGRYSATLDKDAKHSTLHITATLLDDTATYICVVG-----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J240-1", "uniprot_id": "TVA10_HUMAN", "id": "A0A0B4J240-1", "name": "T cell receptor alpha variable 10", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MKKHL-TTFLVILWLYFYRGNGKNQVEQSPQSLIILEGKNCTLQCNYTVSP---FSNLRWYKQDTGRGPVSLTIMTFSENTKSNGRYTATLDADTKQSSLHITASQLSDSASYICVVS-----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B6U4-1", "uniprot_id": "TVA7_HUMAN", "id": "A0A075B6U4-1", "name": "T cell receptor alpha variable 7", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MEKMR-RPVLIIFCLCLGWANGENQVEHSPHFLGPQQGDVASMSCTYSVSR---FNNLQWYRQNTGMGPKHLLSMYSAGYEKQKGRLNATLLKNG--SSLYITAVQPEDSATYFCAVD-----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J274-1", "uniprot_id": "TVA20_HUMAN", "id": "A0A0B4J274-1", "name": "T cell receptor alpha variable 20", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MEKML-ECAFIVLWLQLGWLSGEDQVTQSPEALRLQEGESSSLNCSYTVSG---LRGLFWYRQDPGKGPEFLFTLYSAGEEKEKERLKATLTKKE--SFLHITAPKPEDSATYLCAVQ-----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B6V5-1", "uniprot_id": "TVA36_HUMAN", "id": "A0A075B6V5-1", "name": "T cell receptor alpha variable 36/delta variable 7", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MMKCP-QALLAIFWLLLSWVSSEDKVVQSPLSLVVHEGDTVTLNCSYEVTN---FRSLLWYKQE-KKAPTFLFMLTSSGIEKKSGRLSSILDKKELFSILNITATQTGDSAIYLCAVE-----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J272-1", "uniprot_id": "TVA24_HUMAN", "id": "A0A0B4J272-1", "name": "T cell receptor alpha variable 24", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MEKNPLAAPLLILWFHLDCVSSILNVEQSPQSLHVQEGDSTNFTCSFPSSN---FYALHWYRWETAKSPEALFVMTLNGDEKKKGRISATLNTKEGYSYLYIKGSQPEDSATYLCAF------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5R1B6-1", "uniprot_id": "Q5R1B6_MOUSE", "id": "Q5R1B6-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MNRFLGISLVTLWFRVAWAKS-QWGEENLQALSIQEGEDVTMNCSYK-TY---TTVVHWYRQDSGRGPALIILIRSNEREKRSGRLRATLDTSSQSSSLSITAAQCEDTAVYFCATD-----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B633-1", "uniprot_id": "A0A075B633_MOUSE", "id": "A0A075B633-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MNRFLGISLVTLWFQVAWAKS-QWGEENLQALSIQEGEDVTMNCSYK-TY---TTVVQWYRQKSGKGPAQLILIRSNEREKRSGRLRATLDTSSQSSSLSITGTLATDTAVYFCATD-----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B641-1", "uniprot_id": "A0A075B641_MOUSE", "id": "A0A075B641-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MHSLLGLL---LWLQLTRVNS-QLAEENSWALSVHEGESVTVNCSYK-TS---ITALQWYRQKSGKGPAQLILIRSNEREKRNGRLRATLDTSSQSSSLSITATRCEDTAVYFCATD-----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5R1H8-1", "uniprot_id": "Q5R1H8_MOUSE", "id": "Q5R1H8-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MHSLLGLLMVSLWLQLTRVNS-QLAEENLWALSVHEGESVTVNCSYK-TS---ITALQWYRQKSGEGPAQLILIRSNEREKRNGRLRATLDTSSQSSSLSITATRCEDTAVYFCATD-----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J275-1", "uniprot_id": "TVA17_HUMAN", "id": "A0A0B4J275-1", "name": "T cell receptor alpha variable 17", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------METLLGVSLVILWLQLARVNS-QQGEEDPQALSIQEGENATMNCSYK-TS---INNLQWYRQNSGRGLVHLILIRSNEREKHSGRLRVTLDTSKKSSSLLITASRAADTASYFCATD-----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J279-1", "uniprot_id": "TVA21_HUMAN", "id": "A0A0B4J279-1", "name": "T cell receptor alpha variable 21", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------METLLGLL--ILWLQLQWVSSKQEVTQIPAALSVPEGENLVLNCSFTDSA---IYNLQWFRQDPGKGLTSLLLIQSSQREQTSGRLNASLDKSSGRSTLYIAASQPGDSATYLCAVR-----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B642-1", "uniprot_id": "A0A075B642_MOUSE", "id": "A0A075B642-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MKTSLHTVFLFLWLWMDWESHGEKVEQHESTLSVREGDSAVINCTYTDTA---SSYFPWYKQEAGKSLHFVIDIRSNVDRKQSQRLIVLLDKKAKRFSLHITATQPEDSAIYFCAAS-----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B622-1", "uniprot_id": "A0A075B622_MOUSE", "id": "A0A075B622-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MKTSLHTVFLFLWLWMDWESHGEKVEQHESTLSVREGDSAVINCTYTDTA---SSYFPWYKQEAGKSLHFVIDIRSNVDRKQSQRLTVLLDKKAKRFSLHITATQPEDSAIYFCAAS-----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5R1F6-1", "uniprot_id": "Q5R1F6_MOUSE", "id": "Q5R1F6-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYENSA---SNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS-----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B652-1", "uniprot_id": "A0A075B652_MOUSE", "id": "A0A075B652-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCSYEDSA---SNYFPWYKQEPGENPKLIIDIRSNMERKQIQELIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS-----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B5Z7-1", "uniprot_id": "A0A075B5Z7_MOUSE", "id": "A0A075B5Z7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MKTAIHALFIFFWLQMDWKSQGEQVEQLPSSLIVQEGASVLINCSYTDSA---SVYFPWYKQEPGKRLQFIIDIRSNMERKQTQRLTLLFDKKTKHLSLHITATQPGDSAIYFCSAS-----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J249-1", "uniprot_id": "TVA5_HUMAN", "id": "A0A0B4J249-1", "name": "T cell receptor alpha variable 5", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MKTFAGFSFLFLWLQLDCMSRGEDVEQS-LFLSVREGDSSVINCTYTDSS---STYLYWYKQEPGAGLQLLTYIFSNMDMKQDQRLTVLLNKKDKHLSLRIADTQTGDSAIYFCAES-----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J241-1", "uniprot_id": "TVAM1_HUMAN", "id": "A0A0B4J241-1", "name": "T cell receptor alpha variable 13-1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MTSIRAVFIFLWLQLDLVN-GENVEQHPSTLSVQEGDSAVIKCTYSDSA---SNYFPWYKQELGKGPQLIIDIRSNVGEKKDQRIAVTLNKTAKHFSLHITETQPEDSAVYFCAAS-----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J235-1", "uniprot_id": "TVAM2_HUMAN", "id": "A0A0B4J235-1", "name": "T cell receptor alpha variable 13-2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MAGIRALFMYLWLQLDWVSRGESVGLHLPTLSVQEGDNSIINCAYSNSA---SDYFIWYKQESGKGPQFIIDIRSNMDKRQGQRVTVLLNKTVKHLSLQIAATQPGDSAVYFCAEN-----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B614-1", "uniprot_id": "A0A075B614_MOUSE", "id": "A0A075B614-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------GEQVEQRPPHLSVREGDSAVIICTYTDPN---SYYFFWYKQEPGAGLQLLMKVFSSTEINEGQGFTVLLNKKDKQLSLNLTAAHPGDSAVYFCAV------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B5Z4-1", "uniprot_id": "A0A075B5Z4_MOUSE", "id": "A0A075B5Z4-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MLQMWGFVLYLFLTVGGAAGQGVEQPAKLMSVEGTFARVNCTYSTSG---FNGLSWYQQREGQAPVFLSYVVLDG-LKDSGHFSTFLSRSNGYSYLLLTELQIKDSASYLCAVR-----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5R1I9-1", "uniprot_id": "Q5R1I9_MOUSE", "id": "Q5R1I9-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MKQVAKVTVLLILVSWSLAKTTQPPSMEAYEGQEVNVSCSHTNIAT--SEYIYWYRQVPHQGPQFIIQGYKDYVVNEVASLFISADRKL--STLSLPWVSLRDAAVYYCIVTD----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B6C4-1", "uniprot_id": "A0A075B6C4_MOUSE", "id": "A0A075B6C4-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MGCVSGIAILLALGIAGDAKTTQPDSMESTEGETVHLPCSHATISG--NEYIYWYRQVPLQGPEYVTHGLQQNTTNSMAFLAIASDRKS--STLILPHVSLRDAAVYHCILRV----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58G3I5-1", "uniprot_id": "A0AC58G3I5_DANRE", "id": "A0AC58G3I5-1", "name": "", "aln": "MIRQLIQLMFYTADALPAATQCCKMSLQSSFTFFFLIFAYGTCEEDFIHQQPLVVAELGSRVTLPCFHSDDYVTTVSWTKHSAGKKPLLIAYSDFNSGRVTYQNAFNNTNRFFITVASGSYNLTIIHLEKEDFATYYCVKDFLNRLMFGEGTILLRKETDRISSTSVIQQPVSDRLHPGDSVTLQCSVSSHICAGHYRVYWFKRSSGYSQPGFIYTHDNRSDQCLESSEKSSFVQSCVYSLSQTELTTSDAGVYYCAVDTCGKIHFGNGTKLTIEASSFWNPVVVILFTISVTSIVANIVLVLQNRRKETTEQLRGQINQIETDDLNYAALHFSKTKPSTSRRSSIKTIQETIYSETTVH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * . *:: . * :. * * ", "identical_positions": 6, "similar_positions": 7, "identity": "1.67%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001120-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LE61-1", "uniprot_id": "A0ABK0LE61_RAT", "id": "A0ABK0LE61-1", "name": "StAR-related lipid transfer protein 3", "aln": "MSKLPGDLAG-DLERSLPALASLGTSLSHS-QSLSS-HFIPPPLEKRRV-------VSDVRRTFCLFVTFDLLFISLLWIIELNTN-TGIRKNLEQEVIHYSFQSSFFDIFVLAFFRFSGLLLGYAVLRLQHWWVIAITTLVSSAFLIVKVILSELLS--KGAFGYLLPIVSFVLAWLETWFLDFKVLPQEAEEERWYLAAQ-AAVARGPLLFSGALSEGQFYSPPESFAGSDSESDEEVAGKKSFSAQEREYIRQGKEATAVVDQILAQEENWKLERRNEYGDTVYTIEVPFHGKTFILKTFLPCPAELVYQEVILQPERMVLWNKTVTACQILQRVEDNTLVSYDVSSGAAGGVVSPRDFVNVR-------------------------------------------------------------------------------------------------------------------------RIERRRD-RYLSSGIATTHCSKPPTHKYVRGENGPGGFIVLKSASNPRVCTFVWILNTDLKGRLPRYLIHQSLGATMFEFAFYLRQRVGELGARA--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61542-1", "uniprot_id": "STAR3_MOUSE", "id": "Q61542-1", "name": "StAR-related lipid transfer protein 3", "aln": "MSKRPGDLAC-DLERSLPALASLGTSLSHS-QSLSS-HFIPPPLEKRRA-------ISDVRRTFCLFVTFDLLFISLLWIIELNTN-TGIRKNLEQEVIHYSFQSSFFDIFVLAFFRFSGLLLGYAVLRLQHWWVIAVTTLVSSAFLIVKVILSELLS--KGAFGYLLPIVSFVLAWLETWFLDFKVLPQEAEEERWYLAAQ-AAVARGPLLFSGALSEGQFYSPPESFAGSDNESDEEVTGKKSFSAQEREYIRQGKEATAVVDQILAQEENWKFERSNEYGDTVYTIEVPFHGKTFILKTFLPCPAELVYQEVILQPERMVLWNKTVTACQILQRVEDNTLVSYDVSSGAAGGVVSPRDFVNVR-------------------------------------------------------------------------------------------------------------------------RIERRRD-RYLSSGIATTHCSKPPTHKYVRGENGPGGFIVLKSANNPRVCTFVWILNTDLKGRLPRYLIHQSLGATMFEFAFHLRQRVGELGARA--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14849-1", "uniprot_id": "STAR3_HUMAN", "id": "Q14849-1", "name": "StAR-related lipid transfer protein 3", "aln": "MSKLPRELTR-DLERSLPAVASLGSSLSHS-QSLSS-HLLPPP-EKRRA-------ISDVRRTFCLFVTFDLLFISLLWIIELNTN-TGIRKNLEQEIIQYNFKTSFFDIFVLAFFRFSGLLLGYAVLRLRHWWVIAVTTLVSSAFLIVKVILSELLS--KGAFGYLLPIVSFVLAWLETWFLDFKVLPQEAEEERWYLAAQ-VAVARGPLLFSGALSEGQFYSPPESFAGSDNESDEEVAGKKSFSAQEREYIRQGKEATAVVDQILAQEENWKFEKNNEYGDTVYTIEVPFHGKTFILKTFLPCPAELVYQEVILQPERMVLWNKTVTACQILQRVEDNTLISYDVSAGAAGGVVSPRDFVNVR-------------------------------------------------------------------------------------------------------------------------RIERRRD-RYLSSGIATSHSAKPPTHKYVRGENGPGGFIVLKSASNPRVCTFVWILNTDLKGRLPRYLIHQSLAATMFEFAFHLRQRISELGARA--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DFS4-1", "uniprot_id": "STAR3_DANRE", "id": "Q9DFS4-1", "name": "StAR-related lipid transfer protein 3", "aln": "---MPSAVDYSELGGSLPAIASLNASYSQASLSLPSPYYCPLPPGERKA-------FSDVRRTFCLFVTFDLLFITLLWIIELNIS-KSIWNSLENEVVHYNFKSSFFDIFLLAVFRFLCLQLGYAAFRLRHWWVIAITTLVTTAFLIAKVILSDLFS--QNAFGYVLPITSFVVAWLETWFLDFKVLTQEAEDERVYLAAVNAACEPAPLICPRPVSDGQFYSPPESLAGSEDDLDEEGLGRRAVTEQEKAFVRQGREAMAVVEQILTQEENWKFEKTNELGDAVYTLEIPFHGKTFILKGLLQCTAELVYQEVILQPEKMVQWNRTVSVCQILQRVDDNTMVSYDVSAGAAGGVVSPRDFVNVR-------------------------------------------------------------------------------------------------------------------------RVERRRD-CYISAGMATNHNSKPHHSRYVRGENGPGGFVVLKSSSNPSVCTFIWVLNTDLKGRLPRYLIHQSLAATMFEFMSHLRQRINEVHVSYR-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W145-1", "uniprot_id": "STRT1_DROME", "id": "Q9W145-1", "name": "Steroidogenic acute regulatory protein-like", "aln": "MSNMDPSDVR-STAQLILANARQGNSAYNMQYDMSRAHSINLITEDFLAGYMQDGRMSVVRRFFCLFVTFDLVFVSLLWLICIVINGDNIFTAFHKQIVEYTIYKSLFDVVAVAICRFLVLIFFYAILYINHWSIIALSTSGSCLFLISKVFVFDWLDSKQQVFEVILIITSFILAWGEAWFLDCRVIPQERHAQHYFRTMT--SNDRTPMEQPAILIEQ--ERPPQSVTDFYSLMDTARHSDE-EDELDDEYTQMGLDCLRKAYEIIESSD-WKVEKVNQKGDTIHSTQRDKIGKIYKLTARIKYPAKALMEDLFYRIEDCPKWNPALLESKIVRKINSYTDITYQVSVGGGGGMVKSRDFVNLRSCRLFYNGQICDDDETAQLSSDDGNSSLNRSCEGSVSTISDGDSNTPLLPSSVSSCKATFPTSSKGAAMPFDTLGNSLGAKSLGPIVNFDEEPPPLDQDEFEDAKDKVDGEANNMTKPNVPSVGKTKDRVWVTSAVSVQYAAVPPSPKYTRGQNIVSGFAFREIVGKSDSCIVEWVLCLDLKGYIPRYVLDAALTSSMTDYISNLRKHVNELRQKGRGRAPRTH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * * . * : .:. : . . .* *** *********:*::***:* : . .* . :.::::.*.: .*:**:. :*. ** * : ** : :.** :**::* : *** **:: : :. : .* :* *.**::** *:**** :*:.** . :: : : : *: . : : **:*.:. . * . . : : : * :. . :*: ..: **.*: *: **:::: : ** : *. : .*: : :::: : * ** :: .:*:::::. * ::*:** *..**:*..*****:* : : :* ::::.::. : : * :*.**:* .** . : .:. * . *:* **** :***::. :* ::* :: **:::.*: ", "identical_positions": 115, "similar_positions": 161, "identity": "19.49%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001120-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97826-1", "uniprot_id": "STAR_RAT", "id": "P97826-1", "name": "Steroidogenic acute regulatory protein, mitochondrial", "aln": "MLLATFKLCAGSSYRHMRNMKGLRHQAVLAIGQELNRRALGDPSPG-WMGQVRRRSSLLGSQLEATLYSDQELSYIQQGEEAMQKALGILNNQEGWKKESQQENGDEVLSKVVPGVGKVFRLEVLLDQPMDRLYEELVDRMEAMGEWNPNVKEIKVLKKIGKDTVITHELAAAAAGNLVGPRDFVSVRCTKRRGSTCVLAGMATHFGEMPEQSGVIRAEHGPTCMVLHPLAGSPSKTKLTWLLSIDLKGWLPKTIINQVLSQTQIEFASHLRKRLESSPASEAQC--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51557-1", "uniprot_id": "STAR_MOUSE", "id": "P51557-1", "name": "Steroidogenic acute regulatory protein, mitochondrial", "aln": "MFLATFKLCAGSSYRHMRNMKGLRHQAVLAIGQELNWRALGDSSPG-WMGQVRRRSSLLGSQLEATLYSDQELSYIQQGEVAMQKALGILNNQEGWKKESQQENGDEVLSKMVPDVGKVFRLEVVVDQPMDRLYEELVDRMEAMGEWNPNVKEIKVLQRIGKDTVITHELAAAAAGNLVGPRDFVSVRCTKRRGSTCVLAGMATHFGEMPEQSGVIRAEHGPTCMVLHPLAGSPSKTKLTWLLSIDLKGWLPKTIINQVLSQTQIEFANHLRKRLEASPASEAQC--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49675-1", "uniprot_id": "STAR_HUMAN", "id": "P49675-1", "name": "Steroidogenic acute regulatory protein, mitochondrial", "aln": "MLLATFKLCAGSSYRHMRNMKGLRQQAVMAISQELNRRALGGPTPSTWINQVRRRSSLLGSRLEETLYSDQELAYLQQGEEAMQKALGILSNQEGWKKESQQDNGDKVMSKVVPDVGKVFRLEVVVDQPMERLYEELVERMEAMGEWNPNVKEIKVLQKIGKDTFITHELAAEAAGNLVGPRDFVSVRCAKRRGSTCVLAGMATDFGNMPEQKGVIRAEHGPTCMVLHPLAGSPSKTKLTWLLSIDLKGWLPKSIINQVLSQTQVDFANHLRKRLESHPASEARC--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DG10-1", "uniprot_id": "STAR_DANRE", "id": "Q9DG10-1", "name": "Steroidogenic acute regulatory protein, mitochondrial", "aln": "MLPATFKLCAGISYRHMRNMTGLRKNAMIAIHHELN--KLSGPGASTWINHIRRRSSLLSSPIAEETYSEADQCYVQQGQEALQKSISILEDQDGWQTEIESINGEKVMSKVLPGIGKVFKLEVTLEQQTGDLYDELVDNMEQMGEWNPNVKQVKILQKIGQETMITHEISAETPGNVVGPRDFVNVRHAKRRGSTCFLAGMSTQHPGMPEQKGFVRAENGPTCIVMRPSADDPNKTKFTWLLSLDLKGWIPKTVINRVLSQTQVDFVNHLRDRMASGGGIDAAIAC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ******** ********.***::*::** :*** *... .. *:.::*******.* : **: : .*:***: *:**::.**.:*:**:.* :. **::*:**::*.:****:*** ::* **:***:.** *********::*:*::**::*.****::* :.**:*******.** :*******.****:*.. ****.*.:***:****:*::* *..*.***:*****:*****:**::**:******::*..***.*: : . :* ", "identical_positions": 159, "similar_positions": 91, "identity": "55.4%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001128-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52803-1", "uniprot_id": "EFNA5_HUMAN", "id": "P52803-1", "name": "Ephrin-A5", "aln": "MLHVEMLTLVFLVLWMCVFSQDPGSKAVADRYAVYWNSSNPRFQRGDYHIDVCINDYLDVFCPHYEDSVPEDKTERYVLYMVNFDGYSACDHTSKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSLGFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPTNSCMKTIGVHDRVFDVNDKVENSLEPADD-TVHESAEPSRG-ENAAQTPRIPSRLLAILLFLLAMLLTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97605-1", "uniprot_id": "EFNA5_RAT", "id": "P97605-1", "name": "Ephrin-A5", "aln": "MLHVEMLTLLFLVLWMCVFSQDPGSKVVADRYAVYWNSSNPRFQRGDYHIDVCINDYLDVFCPHYEDSVPEDKTERYVLYMVNFDGYSACDHTSKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSLGFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPTNSCMKTIGVRDRVFDVNDKVENSLEPADD-TVHESAEPSRG-ENAAQTPRIPSRLLAILLFLLAMLLTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08543-1", "uniprot_id": "EFNA5_MOUSE", "id": "O08543-1", "name": "Ephrin-A5", "aln": "MLHVEMLTLLFLVLWMCVFSQDPGSKVVADRYAVYWNSSNPRFQRGDYHIDVCINDYLDVFCPHYEDSVPEDKTERYVLYMVNFDGYSACDHTSKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSLGFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPTNSCMKTIGVHDRVFDVNDKVENSLEPADD-TVHESAEPSRG-ENAAQTPRIPSRLLAILLFLLAMLLTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PZ39-1", "uniprot_id": "A0A8M1PZ39_DANRE", "id": "A0A8M1PZ39-1", "name": "EPH-related receptor tyrosine kinase ligand 7", "aln": "MPQVEMFYLLFSSLWMSVLGLDPASKVVADRYAVFWNRTNPRFYRGDYHIDVCINDYLDVYCPHYMDTVPEERTERYVLYMVNYDGYSSCDHTAKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSLGFEFRPGREYYYISSTLAENGRRSCLRLKVFVRPTNNCDKS---HDRVDKFDDRSINSIENNNDGTSHESAEPSRSDVNSAGRVQTVGPLLASVLVLLASLSSL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :***: *:* ***.*:. **.**.*******:** :**** ****************:**** *:***::**********:****:****:******************************************:****::.:*******:*********.* *: :*** ..:*: **:* :* * ********. *:* : . *** :*.*** * :*", "identical_positions": 161, "similar_positions": 39, "identity": "70.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001205-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q00495-1", "uniprot_id": "CSF1R_RAT", "id": "Q00495-1", "name": "Macrophage colony-stimulating factor 1 receptor", "aln": "MELGPPLVL-LLATVWHGQGAPVIEPS-----GPELVVEPGETVTLRCVSNGSVEWDGPISPYWTLDPESPGST--LTTRNATFKNTGTYRCTEL-EDPMAGSTTIHLYVKDPAHSWNLLAQEVTVV--EGQEAVLPCLITDPALKDSVSLMREGGRQVLRKTVYFFSAWRGFIIRKAKVLDSNTYVCKTMVNGRESTSTGIWLKVNRVHPEPPQIKLEPSKLVRIRGEAAQIVCSATNAEVGFNVILKRGDTKLEIPL-NSDFQDNYYKKVRALSLNAVDFQDAGIYSCVASNDVGTRTATMNFQVVESAYLNLT-------SEQSLLQEVSVGDSLILTVHADAYPSIQHYNWTYLGPFFEDQR--KLEFITQRAIYRYTFKLFLNRVKASEAGQYFLMAQNKAGWNNLTFELTLRYPPEVSVTWMPVNGSDVLFCDVSGYPQPSVTWMECRGHTDRCDEAQALQVWNDTHPEVLSQKPFDKVIIQSQLPIGTLKHNMTYFCKTHNSVGNSSQYFRAVSLGQSKQLPDESLFTPVVVACMSVMSLLVLLLLLLLYKYKQKPKYQVRWKIIERYEGNSYTFIDPTQLPYNEKWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITEYCCYGDLLNFLRRKAEAMLGPSLSPGQDSEGDSSYKNIHLEKKYVRRDSGFSSQGVDTYVEMRPVSTSSSDSFFKQDLD-KEPSRPLELWDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTSGHVAKIGDFGLARDIMNDSNYVVKGNARLPVKWMAPESILYCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNNKFYKLVKDGYQMAQPVFAPKNIYSIMQSCWDLEPTRRPTFQQICFLLQEQARLERRDQD---YANLPSSGGSSGSDSGGGSSGGSSSEPEEESSSEHLACCEPGDIAQPLLQPNNYQFAC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09581-1", "uniprot_id": "CSF1R_MOUSE", "id": "P09581-1", "name": "Macrophage colony-stimulating factor 1 receptor", "aln": "MELGPPLVL-LLATVWHGQGAPVIEPS-----GPELVVEPGETVTLRCVSNGSVEWDGPISPYWTLDPESPGST--LTTRNATFKNTGTYRCTEL-EDPMAGSTTIHLYVKDPAHSWNLLAQEVTVV--EGQEAVLPCLITDPALKDSVSLMREGGRQVLRKTVYFFSPWRGFIIRKAKVLDSNTYVCKTMVNGRESTSTGIWLKVNRVHPEPPQIKLEPSKLVRIRGEAAQIVCSATNAEVGFNVILKRGDTKLEIPL-NSDFQDNYYKKVRALSLNAVDFQDAGIYSCVASNDVGTRTATMNFQVVESAYLNLT-------SEQSLLQEVSVGDSLILTVHADAYPSIQHYNWTYLGPFFEDQR--KLEFITQRAIYRYTFKLFLNRVKASEAGQYFLMAQNKAGWNNLTFELTLRYPPEVSVTWMPVNGSDVLFCDVSGYPQPSVTWMECRGHTDRCDEAQALQVWNDTHPEVLSQKPFDKVIIQSQLPIGTLKHNMTYFCKTHNSVGNSSQYFRAVSLGQSKQLPDESLFTPVVVACMSVMSLLVLLLLLLLYKYKQKPKYQVRWKIIERYEGNSYTFIDPTQLPYNEKWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITEYCCYGDLLNFLRRKAEAMLGPSLSPGQDSEGDSSYKNIHLEKKYVRRDSGFSSQGVDTYVEMRPVSTSSSDSFFKQDLD-KEASRPLELWDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTSGHVAKIGDFGLARDIMNDSNYVVKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNNKFYKLVKDGYQMAQPVFAPKNIYSIMQSCWDLEPTRRPTFQQICFLLQEQARLERRDQD---YANLPSSGGSSGSDSGGGSSGGSSSEPEEESSSEHLACCEPGDIAQPLLQPNNYQFC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07333-1", "uniprot_id": "CSF1R_HUMAN", "id": "P07333-1", "name": "Macrophage colony-stimulating factor 1 receptor", "aln": "MGPGVLLLL-LVATAWHGQGIPVIEPS-----VPELVVKPGATVTLRCVGNGSVEWDGPPSPHWTLYSDGSSSI--LSTNNATFQNTGTYRCTEP-GDPLGGSAAIHLYVKDPARPWNVLAQEVVVF--EDQDALLPCLLTDPVLEAGVSLVRVRGRPLMRHTNYSFSPWHGFTIHRAKFIQSQDYQCSALMGGRKVMSISIRLKVQKVIPGPPALTLVPAELVRIRGEAAQIVCSASSVDVNFDVFLQHNNTKLAIPQ-QSDFHNNRYQKVLTLNLDQVDFQHAGNYSCVASNVQGKHSTSMFFRVVESAYLNLS-------SEQNLIQEVTVGEGLNLKVMVEAYPGLQGFNWTYLGPFSDHQPEPKLANATTKDTYRHTFTLSLPRLKPSEAGRYSFLARNPGGWRALTFELTLRYPPEVSVIWTFINGSGTLLCAASGYPQPNVTWLQCSGHTDRCDEAQVLQVWDDPYPEVLSQEPFHKVTVQSLLTVETLEHNQTYECRAHNSVGSGSWAFIPISAGAHTHPPDEFLFTPVVVACMSIMALLLLLLLLLLYKYKQKPKYQVRWKIIESYEGNSYTFIDPTQLPYNEKWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITEYCCYGDLLNFLRRKAEAMLGPSLSPGQDPEGGVDYKNIHLEKKYVRRDSGFSSQGVDTYVEMRPVSTSSNDSFSEQDLD-KEDGRPLELRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYIVKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQICSFLQEQAQEDRRERD---YTNLPSS-----SRSGG--SGSSSSELEEESSSEHLTCCEQGDIAQPLLQPNNYQFC-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I8N6-1", "uniprot_id": "CSF1R_DANRE", "id": "Q9I8N6-1", "name": "Macrophage colony-stimulating factor 1 receptor", "aln": "MFFALLFLIGILLGQVQGWSEPRIRLSSGALAGTDVILESGSPLQLVCEGDGPVTFLPRLAKHKRYISKEVGKIRSFRVEKTTVDFTGTYKCVYMNGNDSNLSSSVHVFVRDSRVLFVSPSTSLRYVRKEGEDLLLPCLLTDPEATD-FTFRMDNGSAAPYGMNITYDPRKGVLIRNVHPGFNADYICCARIGGAEKVSKIFSINIIQRLRFPPYVYLKRNEYVKLVGERLQISCTTNNPNFYYNVTWTHSSRMLPKAEEKSTMEGDRLAIESILTIPSVQLSHTGNITCTGQNEAGANSSTTQLLVVEEPYIRLSPKLSSKLTHRGLSIEVSEGDDVDLGVLIEAYPPLTSHKWETPTSHNASLP----ENRFFNHNDRYEALLLLKRLNFEEIGQYTLNVKNSMKSASITFDIKMYTKPVARVKWENVT---TLSCRSYGYPAPSILWYQCTGIRTTCPENTTDLQPIQTQTVEFQKESFGAVGVESVLTVGPNRR-MTVVCVAFNLVGQGSDTFSMEVS--------DQIFTSAMCGSTVAMVVLGLLLIFMIYKYKQKPRYEIRWKIIEATNGNNYTFIDPTQLPYNEKWEFPRDKLKLGKTLGAGAFGKVVEATAYGLGKEDNITRVAVKMLKASAHPDEREALMSELKILSHLGQHKNIVNLLGACTHGGPVLVITEYCCHGDLLNFLRSKAENFLNFVMTIPNFPEPMTDYKNVSTERMFVRSDSGISSTCSDHYLDMRPVTSRPTNSALDSSSECQEDSWPLDMDDLLRFSSQVAQGLDFLAAKNCIHRDVAARNVLLTNSRVAKICDFGLARDIMNDSNYVVKGNARLPVKWMAPESIFECVYTVQSDVWSYGIMLWEIFSLGKSPYPNILVDSKFYKMIKCGYQMSRPDFAPPEMYTIMKMCWNLDAAERPTFSKISQMIQRMLGETSEQQDTQEYKNIPTE-----AEAEQQLESCDPVKHEDES---FETSCDQEEEDQPLMKPNNYQFC-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . ::: :: :* . * *. * .:::::.* .: * * .:*.* : : : .. .. : ..::*.. ****:*. : *:::*::*:*. : : .: . *.:: :****:*** .:: * :.. :*. *:..: . * * : :.* : * : ::: : ** : * : *:: ** ** *::.. :. ::* :.. * . :* :..: *.: *::..:* :*...* * .::: : ***..*:.*: :.:.* **: *:.: * * :*** : .:* .. . *: * * *:: .* *:* : .:* :**::.: * . * * :. .* * *** *.: * :* * * * . :. . :.::.* * ::* *.: . .: * * :.* **..* * : :**..: .. * :* ***::::*******:*::****** :**.*******************::*::*****************:****** : :*******::**.**:*********:******:***********************:******** *** :*. :: : .* .***: *: :** ***:** * *::****:: ..:* ... : :* . **:: ***:********: ***:****************..:**** **************:*****************: **************:******** .***.***:.****::* ****::* *** ::*:**: ** *:.:.****.:*. ::*. .::* * *:*:. : : .. .. : *:** . :.*: : ***::******. ", "identical_positions": 387, "similar_positions": 284, "identity": "38.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001206-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6XYB7-1", "uniprot_id": "LBX2_HUMAN", "id": "Q6XYB7-1", "name": "Transcription factor LBX2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSGREPR--------------TPRTLLSIADILAPRMVPRAP-------SAPQLPESGPG----------PTSPLCALEELTSKTFRGLDARAL-QPSEGRAGPDA-------LGPGPFGRKRRKSRTAFTAQQVLELERRFVFQKYLAPSERDGLATRLGLANAQVVTWFQNRRAKLKRDVEEMRADVASLRALS---------------------PEVLCSLALPEGAPDPGLCLGPAGPDSRP------------------HLS--DEEIQVDD-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WUN8-1", "uniprot_id": "LBX2_MOUSE", "id": "Q9WUN8-1", "name": "Transcription factor LBX2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSVHQRR--------------TP---FSIADILGPSMVPEAP-------SAPQLPEAGPD----------PASPLCALEELASKTFLGHSPRATPQPSEGRAAPEAP------PGPGAGVRRRRKSRTAFTAQQVLELERRFVFQKYLAPSERDGLAARLGLANAQVVTWFQNRRAKLKRDVEEMRADVASLCGLS---------------------PGVLCYPALPDSTSSPDP--GPSGPDSEP------------------NLS--DEEIQVDD-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q804R0-1", "uniprot_id": "LBX2_DANRE", "id": "Q804R0-1", "name": "Transcription factor LBX2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSSSKDMKAGSVLQSSGEERRRGPLDQLPPPANSNKPLTPFSIEDILNKPSVKKSVGS----LCPPRVLEKVTGSSASRNGISAPSSPLCALEELASKTFKGLEVSVI-QAAEGREHINA-------FGQRQASKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESLKKIP---------------------PQALQKLVSMEDMEDAHGGSGPISPSLSPRAFPQSPSSSRGQTTD--EFSEEDEEIEVDD-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KH37-1", "uniprot_id": "A0A0B4KH37_DROME", "id": "A0A0B4KH37-1", "name": "", "aln": "----MPQRTPSPANSDVSVG-SPSPPP-------------------------------------------------LRSLN----------MKRLRLLRS---------------PISLEHDRQKSSPVRVKSFSIADILGRG--HEEDRVEKKPER--IAIPNALPGVP---------APLALINERLQIPLVPN----------CPPPAALHTFLSPALLHSYEQRLAWDYQRQLQEHFQAQAQLLRQMTLNPAIIASEDGSSERSQRSSSSNGSTECCSPTQAEKVEKRS-QEDRMEVPKKSPEEQPKGASKSSGDTPLDALFQLSTKNFDEEQDPATLNIFATRSNPKKKRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLSNAQVITWFQNRRAKLKRDMEELKKDVQCEKIPDQSADPNRSHHNHPHYHQQHQHYAHMQSIGSDRDMDKDRCREKEKDKDKEELRMLKLMTLMRYSDGKLLYQQPPASYLPIPHRQNAD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KS77-1", "uniprot_id": "Q7KS77_DROME", "id": "Q7KS77-1", "name": "", "aln": "MLCPPTMRPASPAESEISVGGAPSPLPTQHHTHPHSHPHPLQHPRASTIDLLQQQQLLMQHHAAAAAAAAAAASGLTRSAVGNLPEDYFHPLKRLRMSSSSSEPRDHTPSPPSAVPEPQTNQTTKSAIEGVKSFSIADILGHSEKQREESVSPPPNANLLAPPASRPIAPSGGLLQPRTEPLDVHPAAAAAMLLPSGQIVRPWDHLLGPTMPVRPFIPSALLH-YEQRLALDYHRQLQEHFNAQAQLLRHMGMNPAIIASEDGSSERSQRSSSSNGSTECCSPRQAEKLEKLTTQEGSEEAQKKKSEEQPTGSGKSNGDTPLDALFQMTTKDFDESQDKSHLDIFSNRPQPKKKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQKRDIEELKKDFDSVKVFS-------------------AHKSFLENVN---DLS------ILKKKPMHESDMVGLAAAAAAAG----MVVPVPGSVPMGGAPPK-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: : :: * : ..* * . :.*: . . * : . . :::******** :*: ***:**::****:*::** :* ***:****:********* ***:**:: *. . : . : : ", "identical_positions": 49, "similar_positions": 41, "identity": "9.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001207-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZR84-1", "uniprot_id": "A0A8I5ZR84_RAT", "id": "A0A8I5ZR84-1", "name": "Transcription elongation factor SPT5", "aln": "---------------------------------------------------------------MSDSEDSNFSEEEDSERSSEAEEAEVEED---RRSAAGS------------------------------------EKEEEPE-EEEEEEEEEYDEEEEEEDDDRPPKKPR---HGGFILDEADVDDEYEDEDQWEDG---AEDILEKALFPASNIDNVVLDEDRSGARRLQNLWRDQREE---ELGEYYMKKYAKSSVGETVYG-GSDELSDDITQQQLLPGVKDPNLWTVKCKIGEERATAISLMRKFIAYQFTDTP--LQIKSVVAPEHVKGYIYVEAYKQTHVKQAIEGVGNLRLGYWNQQMVPIKEMTDVLKVVK-EVANLKPKSWVRLKRGIYKDDIAQVDYVEPSQNTISLKMIPRIDYDRIKARMS---LKDWFAKRKKFKRPPQRLFDAEKIRSLGGDVASDGDFLIFEGNRYSRKGFLFKSFAMSAVITEGVKPTLSELEKFEDQPEGIDLEVV--TESTGKEREHNFQPGDNVEVCEGELINLQGKVLSVDGNKITIMPKHEDLKDMLEFPAQELRKYFKMGDHVKVIAGRFEGDTGLIVRVEENFVILFSDLTMHELKVLPRDLQLCSETASGVDVGGQHEWGELVQLDPRTVGVIVRLERETFQVLNMHGKVVTVRHQAVTQKKDNRFAVALDSDQNNIHVKDIVKVIDGPHSGREGEIRHLYRSFAFLHCKKLVENGGMFVCKARHLVLAGGSKPRDVTNLTVGGFTPMSPRISSPMHPSAEGEMGSEFRDWSWEEPYLFNLRALGQSGVWKGLGFTEQVEELLTQLGGLTLVERDLRMSWLWAQHKRDKHNSWAPTSSHPTGQHGGFGSPGG----MSRGRGRRDNELIGQTVRISQGPYKGYIGVVKDATESTARVELHSTCQTISVDRQRLTTVDSQRPGGMTSTYG----RTPMYGSQTPMY-GSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSRAEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMTPGAPSPGGYNPHTPGSGIEQNSSDWVTTDIQVKVRDTYLDTQIVGQTGVIRSVTGGMCSVYLKDSEKVVSISSEHLEPITPTKNNKVKVILGEDREATGVLLSIDGEDGIIRMDLEDQQIKILNLRFLGKLLEA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55201-1", "uniprot_id": "SPT5H_MOUSE", "id": "O55201-1", "name": "Transcription elongation factor SPT5", "aln": "---------------------------------------------------------------MSDSEDSNFSEEEDSERSSEAEEAEVEED---QRSAAGS------------------------------------EKEEEPE-EEEEEEEE-YDEEEEEEDDDRPPKKPR---HGGFILDEADVDDEYEDEDQWEDG---AEDILEKEEIEASNIDNVVLDEDRSGARRLQNLWRDQREE---ELGEYYMKKYAKSSVGETVYG-GSDELSDDITQQQLLPGVKDPNLWTVKCKIGEERATAISLMRKFIAYQFTDTP--LQIKSVVAPEHVKGYIYVEAYKQTHVKQAIEGVGNLRLGYWNQQMVPIKEMTDVLKVVK-EVANLKPKSWVRLKRGIYKDDIAQVDYVEPSQNTISLKMIPRIDYDRIKARMS---LKDWFAKRKKFKRPPQRLFDAEKIRSLGGDVASDGDFLIFEGNRYSRKGFLFKSFAMSAVITEGVKPTLSELEKFEDQPEGIDLEVV--TESTGKEREHNFQPGDNVEVCEGELINLQGKVLSVDGNKITIMPKHEDLKDMLEFPAQELRKYFKMGDHVKVIAGRFEGDTGLIVRVEENFVILFSDLTMHELKVLPRDLQLCSETASGVDVGGQHEWGELVQLDPRTVGVIVRLERETFQVLNMHGKVVTVRHQAVTQKKDNRFAVALDSDQNNIHVKDIVKVIDGPHSGREGEIRHLYRSFAFLHCKKLVENGGMFVCKARHLVLAGGSKPRDVTNLTVGGFTPMSPRISSPMHPSAEG--------------------------------------------------------------------------------QHGGFGSPGG----MSRGRGRRDNELIGQTVRISQGPYKGYIGVVKDATESTARVELHSTCQTISVDRQRLTTVDSQRPGGMTSTYG----RTPMYGSQTPMY-GSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSRAEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMTPGAPSPGGYNPHTPGSGIEQNSSDWVTTDIQVKVRDTYLDTQIVGQTGVIRSVTGGMCSVYLKDSEKVVSISSEHLEPITPTKNNKVKVILGEDREATGVLLSIDGEDGIIRMDLEDQQIKILNLRFLGKLLEA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00267-1", "uniprot_id": "SPT5H_HUMAN", "id": "O00267-1", "name": "Transcription elongation factor SPT5", "aln": "---------------------------------------------------------------MSDSEDSNFSEEEDSERSSDGEEAEVDEE---RRSAAGS------------------------------------EKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPR---HGGFILDEADVDDEYEDEDQWEDG---AEDILEKEEIEASNIDNVVLDEDRSGARRLQNLWRDQREE---ELGEYYMKKYAKSSVGETVYG-GSDELSDDITQQQLLPGVKDPNLWTVKCKIGEERATAISLMRKFIAYQFTDTP--LQIKSVVAPEHVKGYIYVEAYKQTHVKQAIEGVGNLRLGYWNQQMVPIKEMTDVLKVVK-EVANLKPKSWVRLKRGIYKDDIAQVDYVEPSQNTISLKMIPRIDYDRIKARMS---LKDWFAKRKKFKRPPQRLFDAEKIRSLGGDVASDGDFLIFEGNRYSRKGFLFKSFAMSAVITEGVKPTLSELEKFEDQPEGIDLEVV--TESTGKEREHNFQPGDNVEVCEGELINLQGKILSVDGNKITIMPKHEDLKDMLEFPAQELRKYFKMGDHVKVIAGRFEGDTGLIVRVEENFVILFSDLTMHELKVLPRDLQLCSETASGVDVGGQHEWGELVQLDPQTVGVIVRLERETFQVLNMYGKVVTVRHQAVTRKKDNRFAVALDSEQNNIHVKDIVKVIDGPHSGREGEIRHLFRSFAFLHCKKLVENGGMFVCKTRHLVLAGGSKPRDVTNFTVGGFAPMSPRISSPMHPSAGG--------------------------------------------------------------------------------QRGGFGSPGGGSGGMSRGRGRRDNELIGQTVRISQGPYKGYIGVVKDATESTARVELHSTCQTISVDRQRLTTVGSRRPGGMTSTYG----RTPMYGSQTPMY-GSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSRAEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMTPGAPSPGGYNPHTPGSGIEQNSSDWVTTDIQVKVRDTYLDTQVVGQTGVIRSVTGGMCSVYLKDSEKVVSISSEHLEPITPTKNNKVKVILGEDREATGVLLSIDGEDGIVRMDL-DEQLKILNLRFLGKLLEA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DDT5-1", "uniprot_id": "SPT5H_DANRE", "id": "Q9DDT5-1", "name": "Transcription elongation factor SPT5", "aln": "---------------------------------------------------------------MSDSEDSDFSDNQ-SERSSEAEEVEENEEEEEQGSVAGS------------------------------------DKAEEEG--EDLEDEEEYDEEEEE-DDDRPRKKAR---HGGFILDEADVDDEYEDEDPWEDG---AEDILEKEEAEVSNLDHVVLDEDHSGSRRLQNLWRDSREE---ALGEYYMRKYAKSSGGEHFYG-GSEDLSDDITQQQLLPGVKDPNLWTVKCKIGEERATAISLMRKFVAYQCTDTP--LQIKSVVAPEHVKGYIYVEAYKQTHVKAAIEGVGNLRMGFWNQQMVPIKEMTDVLKVVK-EVTNLKPKSWVRLKRGLYKDDIAQVDYVEPSQNTISLKMIPRIDLDRIKARMS---MKDWFAKRKKFKRPPQRLFDAEKIRSLGGEVSHDGDFMIFEANRYSRKGFLFKSFAMSAVITEGVKPTLSELEKFEDQPEGIDLEVV--TETTGKEREHNLQAGDNVEVCEGELINLQGKILSVDGNKITIMPKHEDLKDPLEFPAHELRKYFRMGDHVKVIAGRYEGDTGLIVRVEENFVILFSDLTMHELKVLPRDLQLCSETASGVDAGGQHEWGELVQLDPQTVGVIVRLERETFQVLNMHGKVLTVRHQAVNRRKDNRFAVALDSEQNNIHVKDIVKVIDGPHSGREGEIRHIFRGFAFLHCKKLVENGGMFVCKARHLVLAGGSKPRDVTNFTVGGFAPMSPRISSPMHPGGGGQ------------------------------------------------------------------------------PQRGGGGGGGGG---MGRGRGRRDNDLIGQTVRISQGPYKGYIGVVKDATESTARVELHSTCQTISVDRQRLTTVGGKERQGRSSTHL----RTPMYGSQTPIY-GTGSRTPMYGSQTPLHDGSRTPHYGSQTPLHDGSRTPGQSGAWDPNNPNTPSRPDDEYEFAYDDEPSPSPQGYGGTPNPQTPGYPEVPSPQVNPQYNPQTPGTPAMYNTDQYSPYAAPSPQGSYQPSPSPQSYHQVAPSPVGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMTPGAPSPGGYNPHTPGSNIDQASNDWVTTDIMVRVKDTFLDGGVINQTGIIRSVTGGMCSVFLQDTEKVVSISSEHLEPVTPTKNNKVKVILGEDREATGVLLSIDGEDGIVRMEL-DEQLKILNLRFLGKLEV--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V460-1", "uniprot_id": "SPT5H_DROME", "id": "Q9V460-1", "name": "Transcription elongation factor SPT5", "aln": "---------------------------------------------------------------MSDSEVSNMSDSGSEDGSISNKSQRSARSKSRSRSRSGSRGSRSVSRSRSRSQSGHSRSGSESPQRRDNRGKSDESGEEEEEPPGEDIDSEEYDEEENDDHPRKKKKKER---FGGFIIDEAEVDDEVDEDDEWEEG---ANEIG-IVGNEIDELGPTARDIEIR--RRGTNLWDTQKED---EIEEYLRKKYADESIAKRHFGDGGEEMSDEITQQTLLPGIKDPNLWMVKCRIGEEKATALLLMRKYLTYLNTDDP--LQIKSIIAPEGVKGYIYLEAYKQTHVKTCIDNVGNLRMGKWKQEMVPIKEMTDVLKVVK-EQVGLKVKQWVRLKRGLYKDDIAQVDYVDLAQNQVHLKLLPRIDYTRMRGALRTTATESDDSKRKKKRRPAAKPFDPEAVRAIGGEVHSDGDFLLFEGNRYSRKGFLYKNFTMSAILSDGVKPTLAELERFEESPEEVNLEIMG-TVKDDPTMAHSFSMGDNVEVCVGDLENLQAKIVAIDGTMITVMPKHQDLKDPLIFKASELRKYFKTGDHARVLAGRYEGETGLIIRVEPTRVVLVSDLTNHELEVLPRDLQLCSDVATGVDCLGQFQWGDMVQLDSQNVGVIVRLERENFHVLGMNGKCIECKPTALHKRKENRHTVALDADQNQIRRRDVVKVMEGPHAGRSGEIKHLYRSLAFLHCRMYTENGGIFVCKTRHLQLAGGSKTTVSNAGIVGGLGFMSPRIQSPMHPSGGRG-------------------------------------------------------------------------------ARGGARGGRGG------FRVTRDREILGKTIKISGGPYKGAVGIVKDATESTARVELHTSCQTISVDRNHIAIVGVTGKEGSVSTYGRTPARTPGYGAQTPSYTAAGSKTPLVGSQTPNWDTDTRTPYGTMTPSHDGSMTP-RHGAWDPTANTTPAR-NNDFDYSLE-EPSPSP-GY----NPSTPGY------QMTSQFAPQTPGT--LYGSDR-----SYSP---FNPSPSP----------------------APSPYPVGYMNTPSPS--TYSPNTPGGIPQSPYNPQTPGASLDSSMGDWCTTDIEVRIH-THDDTDLVGQTGIIRTVSNGVCSVFLRQEDRSVSIVSEHLAPVLPCNGDEFKIIYGDDRESVGRVLSKDGD---VFVCRINEEIKLLPINFLCKMKSID", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P27692-1", "uniprot_id": "SPT5_YEAST", "id": "P27692-1", "name": "Transcription elongation factor SPT5", "aln": "MSDNSDTNVSMQDHDQQFADPVVVPQSTDTKDENTSDKDTVDSGNVTTTESTERAESTSNIPPLDGEEKEAKSEPQQPEDNAETAATEQVSSSNGPATDDAQATLNTDSSEANEIVKKEEGSDERKRPREEDTKNSDGDTKDEGDNKDEDDDEDDDDDDDDEDDDDEAPTKRRRQERNRFLDIEAEVSDDEDEDEDEEDSELVREGFITHGDDEDDEASAPGARRDDRLHRQLDQDLNKTSEEDAQRLAKELRERYGRSS--SKQYR--AAAQDGYVPQRFLLPSVDTATIWGVRCRPGKEKELIRKLLKKKFNLDRAMGKKKLKILSIFQRDNYTGRIYIEAPKQSVIEKFCNGVPDIYIS--QKLLIPVQELPLLLKPNKSDDVALEEGSYVRIKRGIYKGDLAMVDQISENNLEVMLKIVPRLDYGKFDEIDPTTQQRKSRRPTFAHRAPPQLFNPTMALRLDQANLYKRDDRHFTYKNEDYIDGYLYKSFRIQHVETKNIQPTVEELARFGSKEGAVDLTSVSQSIKKAQAAKVTFQPGDRIEVLNGEQRGSKGIVTRTTKDIATIKLN--GFTTPLEFPISTLRKIFEPGDHVTVINGEHQGDAGLVLMVEQGQVTFMSTQTSREVTITANNLSKSIDTTA---TSSEYALHDIVELSAKNVACIIQAGHDIFKVIDETGKVSTITKGSILSKINTARARVSSVDANGNEIKIGDTIVEKVGSRREGQVLYIQTQQIFVVSKKIVENAGVFVVNPSNVEAVASKDNMLSNKMDLS---KMNPEIISKMGPPSSKT-------------------------------------------------------------------------------FQQPIQSRGGR------------EVALGKTVRIRSAGYKGQLGIVKDVNGDKATVELHSKNKHITIDKHKLTYYNREGGEGIT------------YDELVNRR-GRVPQARMGPSYVSAPRNMATGGIAAGAAATSSGLSGGMTPGWS----------------SFDGGKTPAVNAHGGSGGGGVSSWGG------ASTWGGQGNGGASAWGGAG------------------------------------------GGASAWGGQGTGATSTWGGASAWGNKSSWGGASTWASGGESNGAMSTWGG----TGDRSAYGGASTWGGNNNNKSTRDGGASAWGNQDD----------GNRSAWNNQGNKSNYGGNSTWGGH-----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :...* . *: : . . . . : .. . :* : :.: *::::: . . .* * . *: **:*.*: :::: *:. : : .: . : *: : *: : : .:*. .* . : . .. :.*: ***.:. ..:* *:*: *:*: *::* . : *:* *:. : .* **:** **: :: :.* :: :. :: ::*::*:. :** * : . *: .:**:***:**.*:* ** :. : : **::**:* :: .. : *. . :* .:: .* : *. .*:*:*.* :. : :..::**: ** :* .. ::* : : . .:. **.:** *: . :. : *: : .:. * * *** *. ***. *: *..:*::**:: ** * :.* * :*: : ..:*. . :.:: .:. ::*:*..:.*. *:: :: *:*:. ** :: : :. : . . : * . : .::: : *.*:: :: *: .: .**.*:** :. :: ..... . :. *.*.* * * * . : . * . :*:*::* . *** :*:***.. ..* ****:. : *::*::::: . * *. . . .:: : * .. .: :. ... : .*. : : :*: .: . ...: . : * * :. . . . : :.* :. . . . .. :.*. : . * . : :. . . .. ::. .* .*.: .: : . :.: * * : * ", "identical_positions": 157, "similar_positions": 350, "identity": "12.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001207-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q78E60-1", "uniprot_id": "ARNT2_RAT", "id": "Q78E60-1", "name": "Aryl hydrocarbon receptor nuclear translocator 2", "aln": "MATPAAVNPPEMASDIPGSVTLPVAPMAATGQVRMAGAMPARGGKRR-SGMDFDDEDGEGPSKFS---------------RENHSEIERRRRNKMTQYITELSDMVPTCSALARKPDKLTILRMAVSHMKSMRGTGNKSTDGAYKPSFLTEQELKHLILEAADGFLFVVAAETGRVIYVSDSVTPVLNQPQSEWFGSTLYEQVHPDDVEKLREQLCTSENSMTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGNAPLDHLPLNRITTMRKRFRNGLGPVKEGEAQYAVVHCTGYIKAWPPAGMS--IPEEDADVGQGSKYCLVAIGRLQVTSSPVCMDMSGMSVPTEFLSRHNSDGIITFVDPRCISVIGYQPQDLLGKDILEFCHPEDQSHLRESFQQVVKLKGQVLSVMYRFRTKNREWLLIRTSSFTFQNPYSDEIEYVICTNTNVKQLQQQQ-AELEVHQRDGLSSYDLSQVPVPNLPTGVHEAGKPVEKADAIFSQERDPRFAEMFAGISASEKKMMSSASASGSQQIYSQGSPFPAGHSGKAFSSSVVHVPGVNDIQSSS-STGQNISQISRQLNQGQVAWTGSRPPFPGQ-----PSKTQSSAFGIGSSHPYPADPSSYSPLSSPAASSPSGNAYPSLANRTPGFAESG---QSGGQFQGRPSEVWSQWQSQHHGQQSGEQHSHQQPGQTEVFQDMLPMPGDPTQGTGNYNIEDFADLGMFPPFSE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61324-1", "uniprot_id": "ARNT2_MOUSE", "id": "Q61324-1", "name": "Aryl hydrocarbon receptor nuclear translocator 2", "aln": "MATPAAVNPPEMASDIPGSVALPVAPMAATGQVRMAGAMPARGGKRR-SGMDFDDEDGEGPSKFS---------------RENHSEIERRRRNKMTQYITELSDMVPTCSALARKPDKLTILRMAVSHMKSMRGTGNKSTDGAYKPSFLTEQELKHLILEAADGFLFVVAAETGRVIYVSDSVTPVLNQPQSEWFGSTLYEQVHPDDVEKLREQLCTSENSMTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGNAPLDHLPLNRITTMRKRFRNGLGPVKEGEAQYAVVHCTGYIKAWPPAGMT--IPEEDADVGQGSKYCLVAIGRLQVTSSPVCMDMSGMSVPTEFLSRHNSDGIITFVDPRCISVIGYQPQDLLGKDILEFCHPEDQSHLRESFQQVVKLKGQVLSVMYRFRTKNREWLLIRTSSFTFQNPYSDEIEYVICTNTNVKQLQQQQ-AELEVHQRDGLSSYDLSQVPVPNLPAGVHEAGKSVEKADAIFSQERDPRFAEMFAGISASEKKMMSSASASGSQQIYSQGSPFPAGHSGKAFSSSVVHVPGVNDIQSSS-STGQNISQISRQLNQGQVAWTGSRPPFPGQ-----PSKTQSSAFGIGSSHPYPADPSSYSPLSSPAASSPSGNAYPSLANRTPGFAESG---QSGGQFQGRPSEVWSQWQSQHHGQQSGEQHSHQQPGQTEVFQDMLPMPGDPTQGTGNYNIEDFADLGMFPPFSE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HBZ2-1", "uniprot_id": "ARNT2_HUMAN", "id": "Q9HBZ2-1", "name": "Aryl hydrocarbon receptor nuclear translocator 2", "aln": "MATPAAVNPPEMASDIPGSVTLPVAPMAATGQVRMAGAMPARGGKRR-SGMDFDDEDGEGPSKFS---------------RENHSEIERRRRNKMTQYITELSDMVPTCSALARKPDKLTILRMAVSHMKSMRGTGNKSTDGAYKPSFLTEQELKHLILEAADGFLFVVAAETGRVIYVSDSVTPVLNQPQSEWFGSTLYEQVHPDDVEKLREQLCTSENSMTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGNAPLDHLPLNRITTMRKRFRNGLGPVKEGEAQYAVVHCTGYIKAWPPAGMT--IPEEDADVGQGSKYCLVAIGRLQVTSSPVCMDMNGMSVPTEFLSRHNSDGIITFVDPRCISVIGYQPQDLLGKDILEFCHPEDQSHLRESFQQVVKLKGQVLSVMYRFRTKNREWMLIRTSSFTFQNPYSDEIEYIICTNTNVKQLQQQQ-AELEVHQRDGLSSYDLSQVPVPNLPAGVHEAGKSVEKADAIFSQERDPRFAEMFAGISASEKKMMSSASAAGTQQIYSQGSPFPSGHSGKAFSSSVVHVPGVNDIQSSS-STGQNMSQISRQLNQSQVAWTGSRPPFPGQQIPSQSSKTQSSPFGIGTSHTYPADPSSYSPLSSPATSSPSGNAYSSLANRTPGFAESG---QSSGQFQGRPSEVWSQWQSQHHGQQSGEQHSHQQPGQTEVFQDMLPMPGDPTQGTGNYNIEDFADLGMFPPFSE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DG12-1", "uniprot_id": "ARNT2_DANRE", "id": "Q9DG12-1", "name": "Aryl hydrocarbon receptor nuclear translocator 2", "aln": "MATPAAVNPSEMGTDLPGPVSMPGAVVGA-GQVRMTGAMPGRGGKRRSAGMDFDDEDGEGPSKFSRYDDDQIPGDKERYARENHSEIERRRRNKMTQYITELSDMVPTCSALARKPDKLTILRMAVSHMKSMRGTGNTSTDGAYKPSFLTEQELKHLILEAADGFLFVVAAETGRVIYVSDSVTPVLNHPQSEWFGSTLFEQVHPDDVDKLREQLSTSENSMTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGSAPLDHISLNRLSSMRKRYRNGLGPSKEGEAQYSVVHCTGYIKAWPPAGMT--IPDEDTEAGQTSKYCLVAIGRLQVTSSPVSMDMNGLSVPTEFLSRHNSDGIITFVDPRCINVIGYQPQDLLGKDILEFCHPEDQSHLRESFQQVVKLKGQVLSVMYRFRMKNREWMLIRTSSFTFQNPYSDEIEYIICTNTNVKQLQQQQQAELEVHQRDGLTAYDLSQVPVSGVSAGVHESGKTIDKTESLFSQERDPRFSDIYTGISTSEKKMMVPSSTSGGQQLYSQGSPFQPGHSGKSFSSSVIHVPGVNDIQSTAGSAGQNLSQISRQINTGQVSWSGNRPPFSGQQIPAQSNKAQSSPFGIGSSHSYQADPSSYSPLSSPATSSPSGNAYSNLANRNTAFDVSGESSQSGGQFQGRPSEVWSQWQSQHHSQQAGDPHPHTQASQTEVFQDMLPMPGDPTQGTTNYNIEDFADLGMFPPFSE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O15945-1", "uniprot_id": "ARNT_DROME", "id": "O15945-1", "name": "Aryl hydrocarbon receptor nuclear translocator homolog", "aln": "----------------------------------------------------MDEANIQDKERFAS--------------RENHCEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVAHMKALRGTGNTSSDGTYKPSFLTDQELKHLILEAADGFLFVVSCDSGRVIYVSDSVTPVLNYTQSDWYGTSLYEHIHPDDREKIREQLSTQESQNAGRILDLKSGTVKKEGHQSSMRLSMGARRGFICRMRVGNVNPESMVSGHLNRLKQ--RNSLGPSRDG-TNYAVVHCTGYIKNWPPTDMFPNMHMERDVDDMSSHCCLVAIGRLQVTST-AANDMSGSNNQSEFITRHAMDGKFTFVDQRVLNILGYTPTELLGKICYDFFHPEDQSHMKESFDQVLKQKGQMFSLLYRARAKNSEYVWLRTQAYAFLNPYTDEVEYIVCTNSSGKTMHGAP--------LDAAAAHTPEQVQQQQQ----QEQHVYVQAAPGVDYARRELTPVGSATNDGMYQTHMLAMQAPTPQQQQQQQQRPGSAQTTPVGYTYDTTHSP--YSAGGPS-PLAKIPKSGTSPTPVAPNSWAALRPQQQQQQ---QQPVTEGYQYQQTSPARSPSGP-TYTQLSAGNGNRQQAQPGAYQAGPPPPPNAPG--MWDWQQAGGHPHPPHPTAHPHHPHAHPGGPAGAGQP-QGQEFSDMLQMLDHTPTTFEDLNINMFS-----TPFE-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: : :. .:*: ****.*********** *****************************:***::*****.*:**:*******:******************:.::*************** .**:*:*::*:*::**** :*:****.*.*.. :*******:*******:*****:.**:**.****** *.. : : .::. ::: **.*** ::* ::*:********* ***:.* : * . *: ************: .. **.* . :**::** ** :**** * :.::** * :**** :* *******::***:**:* ***::*::** * ** *:: :**.:::* ***:**:**::***:. * :: *. ::: .** :* :: : .: .*: :. . :.:*: :.: ** .* * . : .:: .. * * . ..: . .: .. : . :*:. ** * ::. : :. :.* :*: **: . ..:. . *. . .* . * *:* . :.:* :.* *. * : *.*** * .... : **: *: .**. ", "identical_positions": 276, "similar_positions": 186, "identity": "37.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001207-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54764-1", "uniprot_id": "EPHA4_HUMAN", "id": "P54764-1", "name": "Ephrin type-A receptor 4", "aln": "------------------MAGIFYFALFSCLFGICDAVTGSRVYP------------------------------------ANEVTLLDSRSVQGELGWIASPL-----EGGWEEVSIMDEKNTP-IRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERF--IRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCGADGEWLVPIGNCLCNAGHEE--RSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNL-ISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVS--------------------------------VTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYR-IVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEAD-----------------------EEKHLNQG------VRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPG--KREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTR---------GGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLD-----PSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSVQAMRTQMQQMHGRMVPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03137-1", "uniprot_id": "EPHA4_MOUSE", "id": "Q03137-1", "name": "Ephrin type-A receptor 4", "aln": "------------------MAGIFYFILFSFLFGICDAVTGSRVYP------------------------------------ANEVTLLDSRSVQGELGWIASPL-----EGGWEEVSIMDEKNTP-IRTYQVCNVMEASQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERF--IRESQFGKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCGADGEWLVPIGNCLCNAGHEE--QNGECQACKIGYYKALSTDASCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNL-ISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTRVSITDLLAHTNYTFEIWAVNGVSKYNPSPDQSVS--------------------------------VTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYR-IVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEAD-----------------------EEKHLNQG------VRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPG--KREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTR---------GGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGSESSRPNTALLD-----PSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHMSQDDLARIGITAITHQNKILSSVQAMRTQMQQMHGRMVPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O13148-1", "uniprot_id": "EPA4A_DANRE", "id": "O13148-1", "name": "Ephrin type-A receptor 4a", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IGIGEFGEVCSGRLKMPG--KREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIRLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGILRGIASGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEEDPDAAYTTREITGTYQSQGGKIPIRWTAPEAITYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPVSLHQLMLDCWQKERAERPKFSQIVNMLDKLIRNPNSLKRTGGEIARPNTTLLE-----PSSPE-----------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P29321-1", "uniprot_id": "EPHA8_RAT", "id": "P29321-1", "name": "Ephrin type-A receptor 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RIHIEKIIGSGESGEVCYGRLQVPG--QRDVPVAIKALKAGYTERQRQDFLREAAIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDAFLRTHDGQFTILQLVGMLKGVGAGMRYLSDLGYIHRDLAARNILVDGRLVCKVSDFGLSRALEDDPEAAYTTA---------GGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNQDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRFSHVVSVLEALVHSPESLRATATVSRCPAPAFARSCFDLRAGGNGNGDLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLHMNAQDVRALGITLMGHQKKILGSIQTMRSQLSCTQGPRRHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9V4E5-1", "uniprot_id": "Q9V4E5_DROME", "id": "Q9V4E5-1", "name": "receptor protein-tyrosine kinase", "aln": "MKMVGCHPNDKKVKYDGIKSKTSSVTILTSVLNDAISALKSAFYKNQAPISEQNRSQIVSRMSLLRTILLIIISIHFKLAHADQVVLLDTTR-EATLEWTRYPYGPQAQTPGWVEESFTDFVKGINWRSYVVCDVAYHNVNNWLWSPFIDRGSANRLYIEIQFTIRDCSLFPGNALSCKETFSLLFYEFDAATREPPPWQTDSYRLIARIAAGEGRFNQNSD---VDINTEVKSIA-VNKKGVYFAFRDQGACISVLAVKVYYITCPAVTENFAHFNETPTGREITIIEKQNGTCVDNAEPYETPTYLCKGDGKWTILTGGCRCKAGYEPNYTNKTCTECPLGTFKSP-EVTKCTPCPPNSNASKTGSPFCKCASGFYRHPNDGRHMPCYSPPAAPTNLTLLFVDQTSAIISWSAPAKNESFSSETNSKIYHS-DIVYKIKCNICSPNVVYNPSTDTFNETKITLTNLEPVTTYTVQIHAINSVSHINEFKRHSNESSLVAVSDIVFSNTSLLNIPLDLNEVKTGQAEIVFTTESVLLSTVFNLRILAITNKDADLEWDKPVQSDFPLEFYEVRWFPKVELDAINKSALNTKETKAHIVGLLENTEYGFQVRCKTNNGFGSYSNMIYAQTLQSVGSVYDDSVQIRFIAGAIVTGVLFLVIFIIATVYFMRSKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTPIVKKLHLNVTTPLFGNSRSYVDPHTYEDPNQAIREFAREIDANYITIEAIIGGGEFGDVCRGRLKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSLDTFLRVNDGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREIEN-ASDAYTTR---------GGKIPVRWTAPEAIAFRKFTSASDVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVSTLDNLARQPQSLLTTRPSPESDGNHILD------GQRGQNIFISTDLWLEHIKMSRYCHHFKEANLINAQQISRLTAQQLSDMGITLVGHQKKILHQARQLDTII----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ** *:** ***::* ::: ****:**.* ::: * *** **:*********:* *:****: . .**:**********:*** :**:* :**: :*:*:.:** ****:.*:********:**:..*:**::***:** :*: .. **** *****:********::*.*:*******:*:*:***::*******: :*****.::*:*****.**.** :*:*******:*:*:.** *. :*. *: * :.*:** * : . ", "identical_positions": 160, "similar_positions": 76, "identity": "14.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001208-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VUJ1-1", "uniprot_id": "Q9VUJ1_DROME", "id": "Q9VUJ1-1", "name": "Proteasome subunit beta", "aln": "-------MDLDNARDLP--RAGFNFDNCKRNATLLNRG----FKPPTTTKTGTTIVGIIYKDGVILGADTRATEGPIVSDKNCAKIHYLAKNIYCCGAGTAADTEMTTDLISSQLELHRLQTDREVRVVAANTMLKQMLFRYQGHISAALVLGGVDKTGPHIYSIHPHGSSDKLPYATMGSGSLAAMTVFESRWKPDLSEEEGKKLVRDAIASGVFNDLGSGSNIDLCVIRK-GSVEYLRNYELANKKGKRQLDYRFKTGTSTVLHTNI--KDLLVT-ERVQAVPMEIS-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W470-1", "uniprot_id": "Q9W470_DROME", "id": "Q9W470-1", "name": "Proteasome subunit beta", "aln": "MLFPFSARKANTSADFVGLRSGFNFINCRRNAELLSKG----YEPPKAIKTGTSIVGIIYKDGVILGADTRATEGPIVSDKNCSKIHHLQDHIYCCGAGTAADTEMITLTTSAELDLHRLNTERRVPVVCASMMLRRTLFRYQGHIGAALVMGGVDTTGPQLYCIYPCGSNDKIPYAAMGSGTLAAMSVLEHGWKPDLDLEQGKQLVREAISAGVFNDLGSGSNIDLCVITA-KGAVYLRTDTIASEKGERLGKYGIKPNSTMVTSISV--LSLQVTDERIYAVDDQQPGTSGVQLDSQQADEELPEGSQTKSP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25043-1", "uniprot_id": "PSB2_YEAST", "id": "P25043-1", "name": "Proteasome subunit beta type-2", "aln": "-------------------MAGLSFDNYQRNNFLAENS----HTQPKATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESI--VNICDIQEEQVDITA----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q1LWY1-1", "uniprot_id": "Q1LWY1_DANRE", "id": "Q1LWY1-1", "name": "Proteasome subunit beta", "aln": "--------MALTSHVLEPSLCGFNFENATRNIVLENGAEEGKIKPPKALKTGTTIAGVVFKDGVVLGADTRATSDEVVADKMCAKIHYIAPNIYCCGAGTAADTEKTTDMLSSNLTIFSMNSGRNPRVVMAVNIIQDMLFRYHGMIGANLILGGVDCTGSHLYTVGPYGSMDKVPYLAMGSGDLAAMGILEDRFKVNMDLEQAKALVSDAIQAGIMCDLGSGNNIDLCVITK-EGVDYIRPHKESPYNYKRQAKYKYKSGTTPILTKTVNKLELDLVQETVQMMETSASS------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*:.* * ** * . . *.: .***:*.*: :::**::.****:*.. :*:** *:*:* : :*:*.********* * .::: :. : : *. ** * ::: **:*:* *.* *::.*** **.::: : . ** * * ::*** **** ::* :* :: *:. *. :** :*: *****.*:*:**: .. *:* . . :: .* .:: : .: .: * : ", "identical_positions": 84, "similar_positions": 86, "identity": "26.75%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001212-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06687-1", "uniprot_id": "AT1A3_RAT", "id": "P06687-1", "name": "Sodium/potassium-transporting ATPase subunit alpha-3", "aln": "------MGDKK------------DDKSSPKK----------SKAKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQLSIHETEDPNDNRYLLVMKGAPERILDRCATILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQRKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PIC6-1", "uniprot_id": "AT1A3_MOUSE", "id": "Q6PIC6-1", "name": "Sodium/potassium-transporting ATPase subunit alpha-3", "aln": "------MGDKK------------DDKSSPKK----------SKAKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQLSIHETEDPNDNRYLLVMKGAPERILDRCATILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQRKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13637-1", "uniprot_id": "AT1A3_HUMAN", "id": "P13637-1", "name": "Sodium/potassium-transporting ATPase subunit alpha-3", "aln": "------MGDKK------------DDKDSPKK----------NKGKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQLSIHETEDPNDNRYLLVMKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQRKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P271-1", "uniprot_id": "Q6P271_DANRE", "id": "Q6P271-1", "name": "Sodium/potassium-transporting ATPase subunit alpha", "aln": "------MGYGRSDSYRVATTQDNDDKESPKK----------GKG--GKDLDDLKKEVPLTEHKMSIEEVCRKYNTDIVQGLTNARAAEYLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYAIQAATEDEPAGDNLYLGIVLSAVVIITGCFSYFQEAKSSKIMESFKNMVPQQALVIREGEKLQINAEEVVGGDLVEVKGGDRIPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNIAFFSTNCVEGTARGIVVCTGDRTVMGRIATLTSGLETGKTPIAKEIEHFIHIITGVAVFLGVTFFILSIILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGASFDKSSGTWLALARVAALCNRAVFKAGQESLPILKRDVAGDASESALLKCIELSCGSVKAMRDKNKKVAEIPFNSTNKYQLSVHELDESEENHYLLVMKGAPERILDRCSTILQQGKEQPMDEELKEAFQNAYLELGGLGERVLGFCHLVMPGDKYPKGFAFDTDDINFQTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDLSQDQMDEVLKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLFFILVNIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPLRDKLVNERLISIAYGQIGMIQALGGFFSYFVILAENGFLPSVLVGIRLNWDDRSNNDLEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADVIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13607-1", "uniprot_id": "ATNA_DROME", "id": "P13607-1", "name": "Sodium/potassium-transporting ATPase subunit alpha", "aln": "MALRSDYEHGRADSYRVATVIATDDDNRTADGQYKSRRKMPAKVNKKENLDDLKQELDIDFHKISPEELYQRFQTHPENGLSHAKAKENLERDGPNALTPPKQTPEWVKFCKNLFGGFAMLLWIGAILCFVAYSIQASTSEEPADDNLYLGIVLSAVVIVTGIFSYYQESKSSKIMESFKNMVPQFATVIREGEKLTLRAEDLVLGDVVEVKFGDRIPADIRIIEARNFKVDNSSLTGESEPQSRGAEFTHENPLETKNLAFFSTNAVEGTAKGVVISCGDHTVMGRIAGLASGLDTGETPIAKEIHHFIHLITGVAVFLGVTFFVIAFILGYHWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIIEADTTEDQSGVQYDRTSPGFKALSRIATLCNRAEFKGGQDGVPILKKEVSGDASEAALLKCMELALGDVMNIRKRNKKIAEVPFNSTNKYQVSIHETEDTNDPRYLLVMKGAPERILERCSTIFINGKEKVLDEEMKEAFNNAYMELGGLGERVLGFCDFMLPSDKYPNGFKFNTDDINFPIDNLRFVGLMSMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHPITAKAIAKSVGIISEGNETVEDIAQRLNIPVSEVNPREAKAAVVHGAELRDVSSDQLDEILRYHTEIVFARTSPQQKLIIVEGCQRMGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLAFILCDIPLPLGTVTILCIDLGTDMVPAISLAYEHAEADIMKRPPRDPFNDKLVNSRLISMAYGQIGMIQAAAGFFVYFVIMAENGFLPKKLFGIRKMWDSKAVNDLTDSYGQEWTYRDRKTLEYTCHTAFFISIVVVQWADLIICKTRRNSIFQQGMRNWALNFGLVFETVLAAFLSYCPGMEKGLRMYPLKLVWWFPAIPFALAIFIYDETRRFYLRRNPGGWLEQETYY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **.. . . * .:*****:*: : **:* **: ::::*. :**::::* * * ********** ********::*****::**********:**.***.*.::*:.*********:****:** ***:**:*************** * *******: :.**::* **:**:* ***:***:***.*:. **************:*..: **:*****:*::*****.*****:*:*:. **:******* *:***:.*:**** **.***::**********:**::::**** **:********************************* ******************************************** **********..:*::* : **:::* ***** **.**:.:*:**::*:*****:*****:**: *.* :*.:***:**:*********:*:** ::.:: :*************:**:**: :***: :***:****:***:*************. :* :::*:** *: **:** *** *******************.*************************.*************** *******:****:***.*:**::*:*.:.:*:**:*: *********************** ****************************:**************************************************:*** **: :*******:******************** **:***** **:* *****.****:********** .*** ****:******* *.*** **.:: *** *****:***.:** :*:*******:*********:*********:*****:* * ***. **.***********: .******* *** *:*::: **:*** *:: ********:*:****", "identical_positions": 746, "similar_positions": 181, "identity": "71.66%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001221-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q90X44-2", "uniprot_id": "NRF1_DANRE", "id": "Q90X44-2", "name": "Nuclear respiratory factor 1", "aln": "----------------------------------------------------------MEDHTVHQTEHMTTIEAHAVSQQVGQVHVATYTEHGMLSADEDSPSSPDDDAYDDSDILNSTGTDEVTAHLAAAGPVGMAAAAAVATGKKRKRPHIFESNPSIRKRQQTRLLRKLRATLDEYTTRVGQQAIVLCISPSKPNPVFRVFGAAPLENVVRKYKSMILEDLENALAEHAPPGGGELS--SELPPLTIDGIPVSVDKMTQAQLRAFIPEMLKYSTGRGKPGWGKESCKPIWWPEDIPWANVRSDVRTEEQKQRVSWTQALRTIVKNCYKQHGREDLLYAFEDQVTTQVATTATHS------------IAHLVPSQTVVQTISNPDGTVSLIQVGTGATVATLADASELPGTVTVAQVN--------YSTVTDGEVEQNWATLQ-----------------------GGEMTIQTTQAS-EATQAVASLAEAAVAASQEMQTGATVTMALNRYSLEGALKFGEAAAHAVATLAEATLQGGGQIVLAGETAAAVGALTGVPDG---------------------------------------------------------------------SGLVQIPVSMYQTVVT--SLAQGNRPVQVAMAPVTTRIDN-TMTLDG-----------------QAVEVVTLEQ--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q62792-1", "uniprot_id": "NRF1_RAT", "id": "Q62792-1", "name": "Nuclear respiratory factor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VEQNWATLQ-----------------------GGEMTIQTTQAS-EATQAVASLAEAAVAASQEMQQGATVTMALN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16656-1", "uniprot_id": "NRF1_HUMAN", "id": "Q16656-1", "name": "Nuclear respiratory factor 1", "aln": "----------------------------------------------------------MEEHGVTQTEHMATIEAHAVAQQVQQVHVATYTEHSMLSADEDSPSSPEDTSYDDSDILNSTAADEVTAHLAAAGPVGMAAAAAVATGKKRKRPHVFESNPSIRKRQQTRLLRKLRATLDEYTTRVGQQAIVLCISPSKPNPVFKVFGAAPLENVVRKYKSMILEDLESALAEHAP-APQEVN--SELPPLTIDGIPVSVDKMTQAQLRAFIPEMLKYSTGRGKPGWGKESCKPIWWPEDIPWANVRSDVRTEEQKQRVSWTQALRTIVKNCYKQHGREDLLYAFEDQQ-TQTQATATHS------------IAHLVPSQTVVQTFSNPDGTVSLIQVGTGATVATLADASELPTTVTVAQVN--------YSAVADGEVEQNWATLQ-----------------------GGEMTIQTTQAS-EATQAVASLAEAAVAASQEMQQGATVTMALN----------SEAAAHAVATLAEATLQGGGQIVLSGETAAAVGALTGVQDA---------------------------------------------------------------------NGLVQIPVSMYQTVVT--SLAQGNGPVQVAMAPVTTRISDSAVTMDG-----------------QAVEVVTLEQ--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WU00-1", "uniprot_id": "NRF1_MOUSE", "id": "Q9WU00-1", "name": "Nuclear respiratory factor 1", "aln": "----------------------------------------------------------MEEHGVTQTEHMATIEAHAVAQQVQQVHVATYTEHSMLSADEDSPSSPEDTSYDDSDILNSTAADEVTAHLAAAGPVGMAAAAAVATGKKRKRPHVFESNPSIRKRQQTRLLRKLRATLDEYTTRVGQQAIVLCISPSKPNPVFKVFGAAPLENVVRKYKSMILEDLESALAEHAP-APQEVN--SELPPLTIDGIPVSVDKMTQAQLRAFIPEMLKYSTGRGKPGWGKESCKPIWWPEDIPWANVRSDVRTEEQKQRVSWTQALRTIVKNCYKQHGREDLLYAFEDQQ-TQTQATTTHS------------IAHLVPSQTVVQTFSNPDGTVSLIQVGTGATVATLADASELPTTVTVAQVN--------YSAVADGEVEQNWATLQ-----------------------GGEMTIQTTQAS-EATQAVASLAEAAVAASQEMQQGATVTMALN----------SEAAAHAVATLAEATLQGGGQIVLSGETAAAVGALTGVQDA---------------------------------------------------------------------NGLVQIPVSMYQTVVT--SLAQGNGPVQVAMAPVTTRISDSAVTMDG-----------------QAVEVVTLEQ--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q24312-1", "uniprot_id": "EWG_DROME", "id": "Q24312-1", "name": "DNA-binding protein Ewg", "aln": "MATTSYRLVVAPAGSQRSSTGNVVVTTTSSGSHSSNGANGGTGGTSAGSSTLGSGLNVTTITATSGGQLQSAGNTSQSNGTTYKIEMLEEDIQSLGSDDDDEDLISSDGSLYEGDLGSMPVNDDVAHQLAAAGPVGVAAAAAIASSKKRKRPHCFETNPSVRKRQQNRLLRKLRAIIYEFTGRVGKQAVVLVATPGKPNTSYKVFGAKPLEDVLRNLKNIVMDELDNALAQQAPPPPQDDPSLFELPGLVIDGIPTPVEKMTQAQLRAFIPLMLKYSTGRGKPGWGRESTRPPWWPKELPWANVRMDARSEDDKQKISWTHALRKIVINCYKYHGREDLLPTFADDEDKVNALISQSGDEDEDMELSNPPTIHTVTTMTPPTGNSNQPQQVNVVKINSAGTVITTHTAQSNTPAPTIIQSTNNQHVTTTATLPASTKIEICQAPAQNQQHHQHHQTHLPNAVHIQPVAGGQPQTIQLTTASGTATATAVQTTAAAVSAAQAHAHSQSQAHSQSSANQTVTAQQIANAQVCIEPITLSDVDYTTQTVLSQNADGTVSLIQVDPNNPIITLPDGTTAQVQGVATLHQGEGGATIQTVQSLTDVNGHENMTVDLTETQDGQIYITTEDGQGYPVSVSNVISVPVSMYQSVMANVQQIQTNSDGTVCLAPMQVENGDQLETITMSPGMHQMMIQGGPGQEPQLVQVVSLKDATLLSKAMEAINSGNVKSEDTIIMEQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *. * * *** * ** ** :... : ***:*:* . : : : . ", "identical_positions": 17, "similar_positions": 14, "identity": "2.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001222-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7K0-1", "uniprot_id": "G3V7K0_RAT", "id": "G3V7K0-1", "name": "Visual system homeobox 2", "aln": "----MTGKAGEALSK--------------------------PKSETVAKSTSGG-------------APARCTGFGIQEILG------LNKEPPSSHPRAALDGLAPG-HLLAARSVLSPAGVGS--------MGLLGPG--------------G----------------------LPGFYAQP-------------TFLEVLSDPQSVHLQPLGRASGPLDTSQTASSDSEDVSS------------------------------------------SDRKMSKSALNQT---------------------------------------------------------------------------------------------------------------------KKRKKRRH-RTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLP---------------------ESILKSAKDGIMDSCAPWLLG-----MHKKSLEAAAE-SGRKPEV-------------------------------------------------------------------------------------------------------------------------------------ERQ-VLPKLDKMEQEERAPDAQAAISQ-----------EELRENSIAALRAKAQEHSTKVLGTVSGPDGLARNAEKPEEEEAMDEDRPAEKLSPPQLEDMA---------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61412-1", "uniprot_id": "VSX2_MOUSE", "id": "Q61412-1", "name": "Visual system homeobox 2", "aln": "----MTGKAGEALSK--------------------------PKSETVAKSTSGG-------------APARCTGFGIQEILG------LNKEPPSSHPRAALDGLAPG-HLLAARSVLSPAGVGS--------MGLLGPG--------------G----------------------LPGFYTQP-------------TFLEVLSDPQSVHLQPLGRASGPLDTSQTASSDSEDVSS------------------------------------------SDRKMSKSALNQT---------------------------------------------------------------------------------------------------------------------KKRKKRRH-RTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLP---------------------ESILKSAKDGIMDSCAPWLLG-----MHKKSLEAAAE-SGRKPEV-------------------------------------------------------------------------------------------------------------------------------------ERQ-ALPKLDKMEQEERAPEAQAAISQ-----------EELRENSIAALRAKAQEHSTKVLGTVSGPDSLARNAEKPEEEDATEEDRPAEKLSPPQLEDMA---------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58304-1", "uniprot_id": "VSX2_HUMAN", "id": "P58304-1", "name": "Visual system homeobox 2", "aln": "----MTGKAGEALSK--------------------------PKSETVAKSTSGG-------------APARCTGFGIQEILG------LNKEPPSSHPRAALDGLAPG-HLLAARSVLSPAGVGG--------MGLLGPG--------------G----------------------LPGFYTQP-------------TFLEVLSDPQSVHLQPLGRASGPLDTSQTASSDSEDVSS------------------------------------------SDRKMSKSALNQT---------------------------------------------------------------------------------------------------------------------KKRKKRRH-RTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLP---------------------ESILKSAKDGIMDSCAPWLLG-----MHKKSLEAAAE-SGRKPEG-------------------------------------------------------------------------------------------------------------------------------------ERQ-ALPKLDKMEQDERGPDAQAAISQ-----------EELRENSIAVLRAKAQEHSTKVLGTVSGPDSLARSTEKPEEEEAMDEDRPAERLSPPQLEDMA---------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O42477-1", "uniprot_id": "VSX2_DANRE", "id": "O42477-1", "name": "Visual system homeobox 2", "aln": "----MTGKDGAVLSESL------------------------NKSKSLCATENGGNNNPHLSKSSIT-HPPKCTGFGIQEILG------LNKEP-SSAPRSTLDSFPAGAHLLASRSMLGPAGVGVGVG-----MGLIGPG--------------G----------------------IPSFYSQP-------------AFLEVLSDAQNVHLQPLSRTVGPLEHNQSASSDSDDVSS------------------------------------------SERKMSKSSLSQS---------------------------------------------------------------------------------------------------------------------KKRKKRRH-RTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLPVQDGFPTTSCFSKHEYPPFFAESILKSAKDGIMDSCAPWLLG-----MHKKSLETAGHQSNEKSDV-------------------------------------------------------------------------------------------------------------------------------------TQTPTNPKPDEAEAEER--RTESPMSK-----------EELRENSIAALRAKAQEHSAKVLGTVS-SERLEHNMETTATE-----EKSSEQIDAKEEEKSS---------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4B2-1", "uniprot_id": "Q9W4B2_DROME", "id": "Q9W4B2-1", "name": "", "aln": "-MQATKMRTPFAIQEIL-------------------GLGAYQQQATASATPSEAPPSPAATPPPTANTPANGSLSAVQQQQQQQQQQQQQQQQLQQQQQQAIDSLRESRSISPDVSRLSAAAAAAAAAAAHCQLPVFNPANFYAAAGYAAAADPGNAAAAHHHHMTTLAAAAYLRGFLPPGFSTPHEFRGHFQQHFGAQFAEQAAARGQEYASSLANASGDEQSPSKNSSSSGNGGSGGSGSGSGGGNPTSNGLGHLGSPTASNGGSGGGAGVGGSGGGSGTSGSNSSTSGNGGNGGSSGSRSSPAGPHHSAALAAHQHAAAAAAAAHHHAAAAAAAHHAHHAHAQAHAHAHAHVHAHAAHAAHAAHAHAHHAEAFLGAAGGAGGNPNSLLAAHGGDVLVGPGGTGPGGKKKNKRRHGRTIFTSSQLEELEKAFKEAHYPDVSARELLSMKTGLAEDRIQVWYQNRRAKWRKTEKCWGHSTKMAEYGLYGAMVRHSLPLP---------------------ETIIKSAKE--DESVAPWLLG-----MHKKSLEAAELLKSDESDRETPTSDDTNTSYSAGSTHNSPISSFSISRLLFDAPPPAAGSAGGKGHHHHHHHHKGHHHAHVHAQAQAHAHMLLHHQQQQQQQQQQQQHHHHLHAAENSLQQQQVAGTGSGSGSGSGSGTGAGSTGPPAHHPYNQQQHLHHLQQLQQQQQQQQQQAQQQQQHHHHQHHHSVHHMHHHNAAAGYAEAAVAAAAAAAAVAAAANARNAAAAAAVAAASASASAAVTIAESEAEEEQDDIEDMELDKDCEVEEDVEPVDNDTNTNNEHDNECDADADVEADVDADADADPEIDICDDHDEEMRLQEQLLLKVKQEQAHLGSR--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "X2JDS9-1", "uniprot_id": "X2JDS9_DROME", "id": "X2JDS9-1", "name": "Visual system homeobox 2", "aln": "----MPQRSPFAIQELLGLAVAAATEAPTDLTTTAGATVAKERQTPTPPKTTNATMATAATSAATAATPTNAAEGNLTSVSEPQQQPQQQQQEQQHHQPHHHQYREHHQMTMAAASRMAYFNAHAAVAAAFMPHQLAAAVHHHHQHQHQHHPHHHP-------------------HHPHGAVGGP------------PPPPPMQHHHPHHPHHPLLHAQGFPQLKSFAAGAGTCLPG----------------------------------------SLAPKDFGMESLNGFG--------------------------------------------------------------------------------------------------------------VGPNSKKKKKKRRHSRTIFTSYQLEKLEEAFKEAHYPDVYAREMLSLKTELPEDRIQVWFQNRRAKWRKTEKVWGGSTIMAEYGLYGAMVRHSLPLP---------------------DTILKSAKD--NDAVAPWLLGMEQKCMHRKSIEAQSALKDDSGVSDHEDSAGSKSAHSEDLSRSRCHALSSSTESLNVVSPAPSSCPTSASTSAPPTSTSGYAG---------------------------------------------AASSAATTPTGASTTNSSSSPHIELGSPSPQQQQHLQLQQQQQQQASLYLGAGAVVTGCAPPSYHPLLDAANAAGAGAAASSKDFHMIMNTAVAAAAAAAQQQHQQQQQQQQQATATAPGLHAHNLAAALMEHDPDAFRNNSIACLRAKAQEHQARLLNNGGLFLQVRRFAQGQAQIQDPSD-MLKLSEEHNNNSPIPIPPAHSTVNTQVNVKMELTANGGSMKNYEEA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04116-1", "uniprot_id": "YHP1_YEAST", "id": "Q04116-1", "name": "Homeobox protein YHP1", "aln": "MESRNTVLPSLPN------------------------IITGTSNSPFQLHTLPNTNFPSDDQGDIRLPPLAASAHIVRPVVN------IYKSPCDEERPKRKSPQAVDFLSQRVTTSMTPLSKPKKLSS----HSPFTPT-------------------------------------VRVCSKEQ-------------PPQSMHSYKKVNILTPLSAAKAVLTPTTRKEKKRSFAFIT----------------------------------------HSQETFPKKEPKIDN---------------------------------------------------------------------------------------------------------------------ARLARRK-RRRTSSYELGILQTAFDECPTPNKAKRIELSEQCNMSEKSVQIWFQNKRQAAKKHKNSGNTSHCKVHSNDSMSMISYSDAAL-----------------------EITSTPTSTKEAITAELLK-------TSPANTSSIFEDHHITP------------------------------------------------------------------------------------------------------------------------------------------CKPGGQLKFHRKSVLVKRTLSN--------------TGHSEIIKSPKGKENRLKFNAYERKPLGEVDLNSFKN--------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * : : :. . . : : . .* : . : . . : **: * :* :* *: **.*. *: * *: : :.*. :*:*:**:* :* :: . * .. . :*: :* . :.*: :: :. ** .. :: .. : : .. ... . ", "identical_positions": 27, "similar_positions": 66, "identity": "3.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001228-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48303-1", "uniprot_id": "S1PR1_RAT", "id": "P48303-1", "name": "Sphingosine 1-phosphate receptor 1", "aln": "MVSSTSIPVVKALRSQVSDYGNYDIIVRHYNYTGKLNIGVEKDHGIKLTSVVFILICCLIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNSSRSFLLISACWVISLILGGLPIMGWNCISSLSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNIS--KASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKAKTCDILYKAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIISCCKCPNGDSAGKFKRPIIPGMEFSRSKSDNSSHPQKDDGDNP--ETIMSSGNVNSSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08530-1", "uniprot_id": "S1PR1_MOUSE", "id": "O08530-1", "name": "Sphingosine 1-phosphate receptor 1", "aln": "MVS-TSIPEVKALRSSVSDYGNYDIIVRHYNYTGKLNIGAEKDHGIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNSSRSFLLISACWVISLILGGLPIMGWNCISSLSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNIS--KASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKAKTCDILYKAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIVSCCKCPNGDSAGKFKRPIIPGMEFSRSKSDNSSHPQKDDGDNP--ETIMSSGNVNSSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21453-1", "uniprot_id": "S1PR1_HUMAN", "id": "P21453-1", "name": "Sphingosine 1-phosphate receptor 1", "aln": "-MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNIS--KASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNP--ETIMSSGNVNSSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DDK4-1", "uniprot_id": "S1PR1_DANRE", "id": "Q9DDK4-1", "name": "Sphingosine 1-phosphate receptor 1", "aln": "---------------------MDDLIARHYNFTGKFRK-VHKDPGLKADSVVFIIVCCFIILENVLVLLTIWRTKKFHKPMYYFIGNLALSDLLAGVVYTANILLSGANTYKLTPTQWFFREGSMFVALAASVFSLLAIAIERHLTMLKMKLHNNGKTCRVFMLISTVWFIAAILGGLPVMGWNCIDSMNNCSTVLPLYHKAYILFCTTVFSVILMAIVILYARIYALVRTRSRKLVFRKVANGRGSNKSSEKSMALLKTVIIVLSCFIACWAPLFILLLLDVACQTLTCSILYKAEWFLALAVLNSAMNPLIYTLTSNEMRRAFIKMLNCGVCVQ--PSGKFSRPIMG-AEFSRSKSDNSSHPNKDEPEYSPRETIVSSGNITSSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*.****:***:. ..*: .:* *****::**:*****::******:*****:******************.****:*****.******:***:*********:*************::*********..:. * *:***: *.*: ******:******.::..********** *********:::*::*****.***:*******:*.*** . :.:*****:*********** ****************.*:. **.**::**:**.******. **:*****.:*******:::.* * . .:***.***: *************:**: : . ***:****:.***", "identical_positions": 253, "similar_positions": 81, "identity": "65.37%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-001229-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08680-1", "uniprot_id": "HEM0_MOUSE", "id": "P08680-1", "name": "5-aminolevulinate synthase, erythroid-specific, mitochondrial", "aln": "MVAAAMLLRSCPVLSQGPTGLLGKVAKTYQFLFSIGRCPILATQ-----GPTCSQIHLKATKAGGDSPSWAKSHCPFMLSELQDRKS-KI-VQRAAPEVQEDVKTFKTDLLSTMDSTTRSHSFPSFQEPEQTEGAVPHLIQNNMTGSQAFGYDQFFRDKIMEKKQDHTYRVFKTVNRWANAYPFAQHFSEASMASKDVSVWCSNDYLGISRHPRVLQAIEETLKNHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKLLPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPGHLKKLLEKSDPKTPKIVAFETVHSMDGAICPLEELCDVAHQYGALTFVDEVHAVGLYGARGAGIGER----------------------DGIMHKLDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGFPVIPCPSHIIPIRVGNAALNSKICDLLLSKHSIYVQAINYPTVPRGEELLRLAPSPHHSPQMMENFVEKLLLAWTEVGLP-------LQD-VSVAACNFCHRPVHFE------LMSEWERSYFGNMGPQYVTTYA---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63147-1", "uniprot_id": "HEM0_RAT", "id": "Q63147-1", "name": "5-aminolevulinate synthase, erythroid-specific, mitochondrial", "aln": "MVAAAMLLRSCPVLSKGPTGLLGKVAKTYQFLFGIGRCPILATQ-----GPTCSQIHLKATKAGADSPSWTKSHCPFMLSELQDRKS-KI-VQRAAPEVQEDVKTFKTDLLSFMESTTRSQSVPRFQDPEQTGGAPPLLIQNNMTGSQAFGYDQFFRDKIMEKKQDHTYRVFKTVNRWANAYPFAQHFSEASMDSKDVSVWCSNDYLGISRHPRVLQAIEETLKNHGAGAGGTRNISGTSKFHVELEQELAELHHKDSALLFSSCFVANDSTLFTLAKLLPGCEIYSDAGNHASMIQGIRNSGAVKFVFRHNDPGHLKKLLEKSDPKTPKIVAFETVHSMDGAICPLEELCDVAHQYGALTFVDEVHAVGLYGTRGAGIGER----------------------DGIMHKLDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGFPVIPCPSHIIPIRVGNAALNSKICDLLLAKHSIYVQAINYPTVPRGEELLRLAPSPHHSPQMMENFVEKLLLAWTEVGLP-------LQD-VSVAACNFCRRPVHFE------LMSEWERSYFGNMGPQYVTTYA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22557-1", "uniprot_id": "HEM0_HUMAN", "id": "P22557-1", "name": "5-aminolevulinate synthase, erythroid-specific, mitochondrial", "aln": "MVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIGRCPILATQ-----GPNCSQIHLKATKAGGDSPSWAKGHCPFMLSELQDGKS-KI-VQKAAPEVQEDVKAFKTDLPSSLVSVSLRKPFSGPQEQEQISGKVTHLIQNNMPGNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIGER----------------------DGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRVGNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAWTAVGLP-------LQD-VSVAACNFCRRPVHFE------LMSEWERSYFGNMGPQYVTTYA---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9YHT4-1", "uniprot_id": "HEM0_DANRE", "id": "Q9YHT4-1", "name": "5-aminolevulinate synthase, erythroid-specific, mitochondrial", "aln": "---MSAFLHHCPFLKSSPGPSARKVAT---YLNLADRCPIIVRQISAKAAQSSEQNGLLPHKEPKRQLATTATQVAVSMSQSCPFVSSKIGLVKASPQVQEDVQP---NLENQDTSGLISSLFSGLQSHQSTG--PTHLLQDNFN-RPTFSYDEFFTQKIVEKKKDHTYRIFKTVNRFAEVFPFAEDYSIAGRLGSQVSVWCSNDYLGMSRHPRVVKAIGDALKKHGAGAGGTRNISGTSNYHVALENELARLHQKDGALVFSSCFVANDSTLFTLAKMLPGCEIYSDMGNHASMIQGIRNSGAKRFIFRHNDASHLEELLSRSDPLTPKIVAFETVHSMDGAICPLEELCDVAHKYGALTFVDEVHAVGLYGAHGAGVGER----------------------DNVMHKIDIVSGTLGKAFGCVGGYIASTAALVDTVRSFAAGFIFTTSLPPMVLAGALESVRVLKSDEGQALRRAHQRNVKHMRQLLLDAGLPVVNCPSHIIPIRVGNAAKNSEVCDILLEKHNIYVQAINYPTVPRGEELLRLAPSPFHNPIMMNYFAEKLLDVWQEVGLP-------LNG-PAQASCTFCDRPLHFD------LMSEWEKSYFGNMEPRYITVAAQ--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O18680-1", "uniprot_id": "O18680_DROME", "id": "O18680-1", "name": "5-aminolevulinate synthase", "aln": "--------MQCPFLNRFTASFIRNYAETLCQSYGS-HCPVVGKT----------------LVSGEKKLSLVAASVTRSHSTGANAHA-----NAGGPATANATAP-----VSAPASAD----------------------PGKASAKETFPYERFFNEQIMKKKRDHSYRVFKKVNRLAGDGLFPHALEYSERTEKPITVWCSNDYLGMSAHPGVKRAVQDALNRHGSGAGGTRNISGNSLHHERLESKLAELHQKEAALLFTSCFVANDSTLFTLAKLLPGCEIFSDAGNHASMIMGIRNSGVPKHIFRHNDVDHLHQLLKQTDKSVPKIVAFETVHSMTGAICPLEELLDVAHEHGAITFIDEVHAVGLYGDHGAGVGER----------------------DGVLHKMDIISGTLGKAFGNIGGYIAGTHNLVDMIRSYAAGFIFTTSLPPTVLCGALEAVNILASEEGRQLRHLHQRNVSYLKSLLKREGFPVEETPSHIIPIKIGDPLKSSQISNVLIEQFGHYLQSINYPTVARGQEKLRLAPTPFHTFEMMNALVTDLKKVWEMVDLS-------TNVPLSPNACMFCNSESCWH------QDTSPDLECGIPNCPRLEISLAA--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P09950-1", "uniprot_id": "HEM1_YEAST", "id": "P09950-1", "name": "5-aminolevulinate synthase, mitochondrial", "aln": "--------MQRSIFAR----------------FGNSSAAVSTLN----------------------RLSTTAAPHAKNGYATATGAG-----AAAATATASSTHA------AAAAAAA----------------------ANHSTQESGFDYEGLIDSELQKKRLDKSYRYFNNINRLAKEFPLAHRQREADK----VTVWCSNDYLALSKHPEVLDAMHKTIDKYGCGAGGTRNIAGHNIPTLNLEAELATLHKKEGALVFSSCYVANDAVLSLLGQKMKDLVIFSDELNHASMIVGIKHANVKKHIFKHNDLNELEQLLQSYPKSVPKLIAFESVYSMAGSVADIEKICDLADKYGALTFLDEVHAVGLYGPHGAGVAEHCDFESHRASGIATPKTNDKGGAKTVMDRVDMITGTLGKSFGSVGGYVAASRKLIDWFRSFAPGFIFTTTLPPSVMAGATAAIRYQRCH--IDLRTSQQKHTMYVKKAFHELGIPVIPNPSHIVPVLIGNADLAKQASDILINKHQIYVQAINFPTVARGTERLRITPTPGHTNDLSDILINAVDDVFNELQLPRVRDWESQGGLLGVGESGFVEESNLWTSSQLSLTNDDLNPNVRDPIVKQLEVSSGIKQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: ..: : . . . ... . . . . : .: * *: :: .:: :*: *::** *:.:** * :.. : ::********.:* ** * * .::..:*.********:* . ** :** **:*:.**:*:**:****:.* *.: : . *:** ****** **:::.. :.:*:*** ..*.:**. **::***:*:** *::. :*:: *::.::**:**:********** :***:.*: . ::.::*:::*****:** :***:*.: *:* .**:*.******:*** *:.** ::. . ** :*::. :::. : *:** ****:*: :*:. .: .::*: :. *:*:**:***.** * **::*:* *. : : : : .: : *. . . * : . : . : . ", "identical_positions": 157, "similar_positions": 171, "identity": "24.8%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010110-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VIB2-1", "uniprot_id": "DAXX_RAT", "id": "Q8VIB2-1", "name": "Death domain-associated protein 6", "aln": "----------------------------------------------------------------------------------------------MATDDSIIVLDDDDEDEAAAQPGPSNPASNPVSPGP------EASGPSESHGDGGSSN---------------------------------------SGSRKCYKLENEKLFEEFLELCKMQTSDHPEVVPFLHKLQQRAQSAFLASAEFRNILSRVLSRSRNRPAKLYVYINELCTVLKAHSIKKK---LNLAPAAS--AESSGDNPPTDPPSDLTNTETTASEASR----TRGSRRQIQRLEQLLALYVAEIQRLQEKELDLS--------------------------------------------ELDDPDSSYLQEARLKRKLIRLFGRLCDLKDCSSLTGKVIEQRIPYRGTRYPEVNRRIER-------------LINKP-GPDTFPDYG--DVLRAVEKAATRHSLGLPRQQLQLLAQDAFRDVGVRLQERRHLDLIY-NFGCHLTDDYRPGVDPALTDPTLARRLRENRTLAMSRLDEVISKYAMMQDKSEEGE------RQKRRARLLATS-QSSDLPKASSDSGEGPSGVASQEDPTTPKAETEDEEDDEESDDE-------EEEEEEEEEEATE-DEDEDLEQLQEDQD-DEEEEEGD-------------------------NEDDKSPASPSPIFRRKEFSNPQKGSGP-QEEQQERGLTGTPASPLEASPGLPSTDAESSGEQLQERLLAGESPVSQLSELDMEALPEETI--PSPEERGISSSRRKSDSSLPTILENGAAMVTSTSFNGRVSSHPCRDASPPSKRFRKEKKQLGPGPLGNSYVKKQTMAQQDSGWKISVLSTPSSPLAS-----VGPVADSSTRVD--------SPSHELVTSSLCNPSPSLILQTPQSQSPRPCIYKTSVATQCDPEEIIVLSDSD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35613-1", "uniprot_id": "DAXX_MOUSE", "id": "O35613-1", "name": "Death domain-associated protein 6", "aln": "----------------------------------------------------------------------------------------------MATDDSIIVLDDDDEDEAAAQPGPSNLPPNPASTGPGPGLSQQATGLSEPRVDGGSSN---------------------------------------SGSRKCYKLDNEKLFEEFLELCKTETSDHPEVVPFLHKLQQRAQSVFLASAEFCNILSRVLARSRKRPAKIYVYINELCTVLKAHSIKKK---LNLAPAASTTSEASGPNPPTEPPSDLTNTENTASEASR----TRGSRRQIQRLEQLLALYVAEIRRLQEKELDLS--------------------------------------------ELDDPDSSYLQEARLKRKLIRLFGRLCELKDCSSLTGRVIEQRIPYRGTRYPEVNRRIER-------------LINKP-GLDTFPDYG--DVLRAVEKAATRHSLGLPRQQLQLLAQDAFRDVGVRLQERRHLDLIY-NFGCHLTDDYRPGVDPALSDPTLARRLRENRTLAMNRLDEVISKYAMMQDKTEEGE------RQKRRARLLGTAPQPSDPPQASSESGEGPSGMASQECPTTSKAETDDDDDDDDDDDEDNEESEEEEEEEEEEKEATE-DEDEDLEQLQEDQGGDEEEEGGD-------------------------NEGNESPTSPSDFFHRR-NSEPAEGLRT-PEGQQKRGLTETPASPPGASLDPPSTDAESSGEQLLEPLLGDESPVSQLAELEMEALPEE---------RDISSPRKKSEDSLPTILENGAAVVTSTSVNGRVSSHTWRDASPPSKRFRKEKKQLGSGLLGNSYIKEP-MAQQDSGQNTSVQPMPSPPLAS-----VASVADSSTRVD--------SPSHELVTSSLCSPSPSLLLQTPQAQSLRQCIYKTSVATQCDPEEIIVLSDSD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UER7-1", "uniprot_id": "DAXX_HUMAN", "id": "Q9UER7-1", "name": "Death domain-associated protein 6", "aln": "----------------------------------------------------------------------------------------------MATANSIIVLDDDDEDEAAAQPGPSHPLPNAASPGA------EAPSSSEPHGARGSSS---------------------------------------SGGKKCYKLENEKLFEEFLELCKMQTADHPEVVPFLYNRQQRAHSLFLASAEFCNILSRVLSRARSRPAKLYVYINELCTVLKAHSAKKK---LNLAPAATTSNEPSGNNPPTHLSLDPTNAENTASQSPR----TRGSRRQIQRLEQLLALYVAEIRRLQEKELDLS--------------------------------------------ELDDPDSAYLQEARLKRKLIRLFGRLCELKDCSSLTGRVIEQRIPYRGTRYPEVNRRIER-------------LINKP-GPDTFPDYG--DVLRAVEKAAARHSLGLPRQQLQLMAQDAFRDVGIRLQERRHLDLIY-NFGCHLTDDYRPGVDPALSDPVLARRLRENRSLAMSRLDEVISKYAMLQDKSEEGE------RKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEE-------EEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAG--------------------KDGDKSPMSSLQISNEKNLEPGKQISRS-SGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELEIEALPLDT---PSSVETDISSSRKQSEEPFTTVLENGAGMVSSTSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNGKKICTLPSPPSPLAS-----LAPVADSSTRVD--------SPSHGLVTSSLCIPSPARLSQTPHSQPPRPGTCKTSVATQCDPEEIIVLSDSD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HYH8-1", "uniprot_id": "A0AC58HYH8_DANRE", "id": "A0AC58HYH8-1", "name": "Death domain-associated protein 6", "aln": "-------------------------------MLLTNKRKESVWHVRIKELQSSNQKVNADFET-----PVWILTVLINSMLSAQQIRSPPFRMAGAGMESIVILDDDDEEAASTSASCSQATAQHLKTPVK---SQPVPAPTHITQSPFASA---------------------------------------KKDTHVLKVENEKLFNEFVEHCSKHSQEHPEVMTYLQTRYSKALPTFLTSVEFRNTLGRCLTRAQANAGKTFVYINELCTVLKQHTPRKRSSIQSLSVKAKPEEKSNGVNVKEDTQGEQDGGKDVKQQEEESKKTKRASRRQIAYLENLLKVYNEEIRRLQEGDLSLD--------------------------------------------DLEKEDSSYIQEHKLKRKMMKIYEKLCELKGCNTLTGRVIEQKIPYSGTRYPEINKKVER-------------FINSSEALLNPPDYS--DILKIVQRANERYNLQLSRKQQAQISQEAFRETGNKLQERRHLDMVY-NFGSHLTDPYKPTLDPALMDPALHRKLRSNRDVAISSLEEVINKYANKQEDMEVEE------TKKRQDRERLKKEAVNGQQSESKEK------------------EKEEQEEKEKEDEE-------EEEEDEEEDDSSDPDIEDEIQASEQQAGPEDDEEDVE-----------------------------EEPANISDNDQPINESSPLSIKSS-VQDTEEDEEQSPLSSTHEGSAETNTNTNGPAKQSLESTEIKPES-------IKPESIKPES------IKPETIKPESIKPENTDSLAEVKTEQVSSNHVEAVSASTETVSIVSEESSTAVTRSANCSPLLPTSPLLIDETGNYRKRKRRSTENHTSAHNGN-----CTEDSDIPLDMG--------VICCSEQEDLTCLKTPPRKTARNSQATPPPKKNKVNVATQCDPEEVIVLSDSE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMD0-1", "uniprot_id": "DAXX_DROME", "id": "Q9VMD0-1", "name": "Daxx-like protein", "aln": "MSASVICVDLSSESDEESPAKRRRLEDPLRLLTPSGRQSFPAKLLNIPKASLGSAMVVPVAETGPARETPVIVDPLRSMHIPSGITITKHQKNVLATNGNMNLSLAESNNNNNTTSLNKNVTPKQINVGTGQKVAWSVSSKAPSPNAVITTVPSHQVRVTPFNPIRLAPGSKIIPASNAMPAKIQPILGMGQPQQQAQAQQPKAIIVGFPKPNTAVAQMAQHQKPLTLQIHQKLIAGQQQHIASISQLQQVSLQQQQPLRPVSIQLQQQQNQRNGSLPGKQQKPLECPVPAQQEKLPRGP-LPTKPAEPLSGPLPTEPDEPLGGPLPTRPKPPVRSLQQPVNKNTAIGVQIQQSQEPLGGTLPTRQKPLGGQLLTQQKPPVGSIQQSVKQNTGIGVQIQQIPKVVVGQQPQKVYLNKLQQEQQKIFLGHLQQQQQKTFLGQLQQEQQKILGQLQQQKQQQQQQQKKILGQSQQQKVPLGQPQPQQKLPQQLNNSLVQLQQQHQQRTSVGQLQQQQPHQSQQKNSMVHVKQQPQQQKKISVGQFQQQPQQQQKTSVAQLQQQPQQQQKISVGQLQQQSQQQQKPSVGQLQQQSQQQQTPLVGQLQRQTQQQQKTSAGQFQQQPQQQQKISAGQLQEHSQQQQKTLAGQLQQQAQQQLNTSAGQLQQQQKPPKASLAQQAAAQKQGAGLGQQQQFQSQPQQRTSAGLLQQQQMPQKKIVMQPQLPKTSVVLPRPQQLPKNPLLVAQQQSPKTPLVNSVMGPQFPSQQPSLPVVNQITHKSMTIQRLPMLQTVQKILPKQIAPQQTPPPAHIVQKQTMPNAAMQNPPFAHRPPIVRPMTVAKISPVPTNNKVCIPMKPQMASYVSPTDPTMTAARTLPFRSSQRKTSEAPMTSTHVQGFTASATPPQRLLATPPHCAAALNEPLLLNLPPTTSITPQLTPTTTPPPAGPSAAVQQQQLAKAAAIKLNSLPEASISPVNRSPTASAKRIQPITVLKKSDEEWQRHLEQQQQKKHVQLQSSSMTTIVLVESPPTTPPTDKPEPERGPMTVEKSSIKPMATDKQSRAIKRPAVMISTKKSGLVVTEIVDLDEIPDIPPEKRGKECFPPIKNAAKAAPSVNAPFTTEYAALLRLCREVDKSTHMERLVKGELTQYYYSAPESFVMSCGFRNLVTMAMARIRSESYLVYVHLKYVLDELASRRLTKMFPTVRAIPPASQFPLPPASQFPLPPTLTTPKQPAIVKAPGQQTVMAGREQDDEVEEVTLVNVGTVSCEERRRDERIRHFYRTLHAITKRIKMLEEAEVDLNDEDSSYLQLERFKKRACQIYEKICDLKGESKSVRRQLKKPIHFKDSDYPHFNNSLSAFVNRMQDFPDYHDVLQILEKCNKEKELGLAKYEMKRIAYDAFNKVGRMLQSRRKNDLYETVTHYTANGKDPASSDPELLAKLKENNKKQTKISDILEKYALEQDLNAEERQEARLKEKKLKQVKADEEAAKLAALAEDDDKPCTSAQAAAKAAALAALKRGPAARGNVIRKKRAANGRIFKIADDGDDSEEESDSEDDDVEEFVNNFQANSDVSDADSEVEAVTSPKRDALPLAEEEDVIDITRDETGKKNDEGTPNGRLKIMSVSSLNANFVHGQDLHRKPNPMPSAKPVIADQIIISDEES", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: : :.:: : . .: .: . ... : :: . : : : :: * : . : . . .: . . * : : : : ::: . : *: . . * . * . . . : .: : *:: : ::*: : *. : :. : :*::: ::: : : .:: *:: ::: * : ::: :: :... . *: .::: :: * .: ::* :*: . : * ::: .: :* : : :. : :* ::: .: . :: . *:. : :: : : . . . . : ::: :.: . . : : . .::: . : :: ::. : * . . . .: . :. : :. :. ::: . : . . . . :. . : : .: : .. .. . :. . : . . . :. . *.: :* :: **.: ", "identical_positions": 25, "similar_positions": 218, "identity": "1.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010110-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6MGC7-1", "uniprot_id": "Q6MGC7_RAT", "id": "Q6MGC7-1", "name": "Zinc finger and BTB domain-containing protein 22", "aln": "MEPSPMSPSGATLPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTELLREGRSSAATTTVTAVAAPSVSVPCASVPSGSGGTVAPATVGSVRSHTSSRASENQSPSSSNYFSPRESTDFSSSSQDAFVASAVGSGNRRDGGPVFPVPVVGSAGTTSGKLLLEADELCDDGGDGRG------AAAPGAGLRRPNCLPASAVPQKHWVYVKRARNCPAPASLVHQDPDLEDEEE--EEDLVLTCEDDEDEDLGNGSGVPAGGEPEATLSISDVRTLTEPAEKGEE--QVNFCESSNDFGPYEGGGAGAGLDDPGGPTPS------------SYGLTHPPRPLLPLDVPGNQILVFPSSSS----------QAPGQPPGNTAEHGAVTLGGASAVGLGIPSGSGGTPGGAGNSDGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECSVCAKKFMWRDSFMRHRGHCERRHRMGAGGAASVPGPGPG--APTGP-----------ALQPKRESSAVGGGSGDEANSATPPSNRRVWSPPSVHKVEMDFSGGGGAAH-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0G7-1", "uniprot_id": "ZBT22_MOUSE", "id": "Q9Z0G7-1", "name": "Zinc finger and BTB domain-containing protein 22", "aln": "MEPSALSPSGATLPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTELLREGRSAATTTTVTTAAAPSVSVPCASVPSGNGGTVAPATVGSVRSHTSSRASENQSPSSSNYFSPRESTDFSSTSQDAFVASAAGSGNRRDGGPVFPAPVVGSAGTTSGKLLLEADELCDDGGDGRG------AVAPGAGLRRSNCMPASAVPQKHWVYVKQARNCPAPASLVHQDPDLEDEEE--EEDLVLTCEDDEDEEMGGGSGVPAGGEPEATLSISDVRTLTEPADKGEE--QVNFCESSNDFGPYEGGGAGAGLDDPGGPTPS------------SYALTHPPRPLLPLDVPGNQILVFPSSSS----------QAPGQPPGNTAEHGAVTLGGTSAVGLGIPSGSGGAPGGTGNSDGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECSVCAKKFMWRDSFMRHRGHCERRHRMGVGGVGSGPGPGPGPGTPSGP-----------ALQPKRESSTVGGGSGDEANSATPPSHRRVWSPPSVHKVEMDFSGGGGAAH-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15209-1", "uniprot_id": "ZBT22_HUMAN", "id": "O15209-1", "name": "Zinc finger and BTB domain-containing protein 22", "aln": "MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTELLREGR-ASATTTITTAAATSVTVPGAGVPSGSGGTVAPATMGSARSHASSRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSGERRGGGPVFPAPVVGSGGATSGKLLLEADELCDDGGDGRG------AVVPGAGLRRPTYTPPSIMPQKHWVYVKRGGNCPAPTPLVPQDPDLEEEEE--EEDLVLTCEDDEDEELGGSSRVPVGGGPEATLSISDVRTLSEPPDKGEE--QVNFCESSNDFGPYEGGGPVAGLDDSGGPTPS------------SYAPSHPPRPLLPLDMQGNQILVFPSSSSSSSS------QAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVPGGTGSGDGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRHRGHCERRHRLG--GVGAVPGPG----TPTGP-----------SLPSKRESPGVGGGSGDEASAATPPSSRRVWSPPRVHKVEMGFGGGGGAN------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LUU5-1", "uniprot_id": "Q1LUU5_DANRE", "id": "Q1LUU5-1", "name": "", "aln": "--------------MQSATADQTFVDSTGSVVQVCFPRAQTSVLDSLNRQREEGHLCDLSIHVQGQVFKAHRCVLAASSPYFHDQVLLKNMSTVSIPAVMDPLAFESVLSCAYTGQLRMLREDIVNYLTVGSVLQMWHIVDKCTELLKEGKGGSSGPQGSGEKENIGQGSGTNKVAQADGGEAPSTP---QPPSRPSFSESQSPSSTNYFSPRD-ANFGG----AMVSTIAVGEGAVHSTPSYCMPSGGEEGFMIEDEEDDDDELLFSRKRDRGGKQKSTSSVSDQEVGVSDSFGVSSYQDGDSSPPQKHPSYIQPSIMPRKQWVVVKTEHSRDDDLIVVSGGEEGGDDEEEREMAIVRERDRTFNISNVRTLSGLREDAEMDAQVDYCQSSEDYLKFERGIIDQTSSQHPPENSSQCPNRAMSGMLGSVQSTSARAQLFPLDMQGNQILLYNQAALESTSPLGLTGGMSGVSLKGSLEHGAVHLPSQGALGSGMEGLDAGSAGSSG-----KVFMCHCGKTFTHKSMRDRHINMHLNLRPFHCPVCAKKFKMKHHLTEHMKTHTGLKPYDCHGCGKKFMWRDSFMRHRSHCERRGRSERASERSVISPPHHLKLPSASEPNQGGAGARSGLPILSPQHSISSNGVSCLSMAASGSLLGMSSQSGSHSLGSGILGIGGNRSGCVEDVCEENVDESSVT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * .: .:.:**:*.**.. :::*:***:** :*:***:**:***: *:***.****************.*:::*:*:**** ***:**:.****:* * ****:********************:**: .:: . : . :. : .* **:* :. : . **.*****:******: ::*.. *:.:: . . . * : * *. * . : *** . .** : ... : . * : . :: . *: : :: : . *. ::**::.. .:*. : :. : *:.**:****: :..* **::*:**:*: :* * .: ..* * : . *:***: *****:: .:: .* . . ***** : . .. . *: . .* .*.:* *:*:*****:*:********:*********.**** **********************:* *.*************.***** * . : .* *:.. .* . :.... . . *:. * : * . *.: .: * ** ", "identical_positions": 238, "similar_positions": 175, "identity": "34.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010111-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A8K3-1", "uniprot_id": "D4A8K3_RAT", "id": "D4A8K3-1", "name": "", "aln": "----MALPGSSQAETWNLDSLVSTASLP--LGPQEQEVGGGPGASGGLPLEKVKRPMNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDDEEKRPFVEEAKRLRARHLHDYPDYKYRPRRKS-----KNPGTGSVHFSQG-----------GGGPVCGGPHWG--PGYTTTQG-SRGFGYQPP----------------NYSTAYMPGSYTSS---------HCRPEAP--SPCTVPQSDP-RLQGELIPSFPHYPSPGSPTPYI----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43267-1", "uniprot_id": "SOX15_MOUSE", "id": "P43267-1", "name": "Transcription factor SOX-15", "aln": "----MALTSSSQAETWSLHPRASTASLP--LGPQEQEAGGSPGASGGLPLEKVKRPMNAFMVWSSVQRRQMAQQNPKMHNSEISKRLGAQWKLLGDEEKRPFVEEAKRLRARHLRDYPDYKYRPRRKS-----KNSSTGSVPFSQE-----------GGGLACGGSHWG--PGYTTTQG-SRGFGYQPP----------------NYSTAYLPGSYTSS---------HCRPEAP--LPCTFPQSDP-RLQGELRPSFSPYLSPDSSTPYNTS---------LAGAPMPVTHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60248-1", "uniprot_id": "SOX15_HUMAN", "id": "O60248-1", "name": "Transcription factor SOX-15", "aln": "----MALPGSSQDQAWSLEPPAATAAASSSSGPQEREGAGSPAAPGTLPLEKVKRPMNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKRLRARHLRDYPDYKYRPRRKA-----KSSGAGPSRCGQG-----------RGNLASGGPLWG--PGYATTQP-SRGFGYRPP----------------SYSTAYLPGSYGSS---------HCKLEAP--SPCSLPQSDP-RLQGELLPTYTHYLPPGSPTPYNPP---------LAGAPMPLTHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DDD7-1", "uniprot_id": "SX19B_DANRE", "id": "Q9DDD7-1", "name": "Transcription factor Sox-19b", "aln": "MYSMMEHELKTAGPPHTLQHSPGMSPPGSGVGNAHH-VSKTACPPGVDPMDKVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLTDVEKRPFIDEAKRLRAVHMKEYPDYKYKPRRKTKALMKKDNPVGKYPLAAGNLLASAVAQGQGGSPRMDGYGWGHAGGYMGMQGDALGYPQQLHRYDLSALQYPAAQPYMNSASSYSQMSYSSSPQQPSPVMSMVKPEPLSHSPTGVPNHHRGAFQGDLRDMISMYIPGGDTSESSNQRAYPGVQQHYLGGTVPLTHI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: . .*. . :. * .: . . ..* *::************* ***:***:***************:**** : *****::******* *:::******:****: *. .* . *. .* ** ** * : *: : . :::* ** ** : *. * .*: . :**:* . * . ...: ", "identical_positions": 88, "similar_positions": 52, "identity": "30.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010112-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LWX7-1", "uniprot_id": "A0ABK0LWX7_RAT", "id": "A0ABK0LWX7-1", "name": "", "aln": "---MVRFCNSWWPHVSGGGSEACRVLAPQDAASVPSENHLLRALHECYAENNGTTQRFIMRCIFNREEFMRFDSAVGEFRALTAMGRPWAESWNKQKDYMERRRSEVDTVCRHNYE-LSQGFTVKRRVRPKVHVSPSKKVTLKHHDLLVCHVTDFYPGSIQVRWFQNSQEETTGVVSTNLIRNGDWTFQILVMLEMTPQRGDVYMWNTP--ALRAPSHLFFPGIQSDSARNKMLTGVVGLVLGLIFLAVGILKHVWSKQGLLSMVRKSQPELPSQSRGGVGEEPG--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04440-1", "uniprot_id": "DPB1_HUMAN", "id": "P04440-1", "name": "HLA class II histocompatibility antigen, DP beta 1 chain", "aln": "---MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNG--TQRFLERYIYNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYE-LGGPMTLQRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWK-AQSDSARSKTLTGAGGFVLGLIICGVGIFMHRRSK--------KVQ-------RGSA-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P79483-1", "uniprot_id": "DRB3_HUMAN", "id": "P79483-1", "name": "HLA class II histocompatibility antigen, DR beta 3 chain", "aln": "---MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYFHNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYG-VGESFTVQRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWR-ARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P01911-1", "uniprot_id": "DRB1_HUMAN", "id": "P01911-1", "name": "HLA class II histocompatibility antigen, DRB1 beta chain", "aln": "---MVCLKLPGGSCMTALTVTLMVLSSPLALSGDTRPRFLWQPKRECHFFNGTERVRFLDRYFYNQEESVRFDSDVGEFRAVTELGRPDAEYWNSQKDILEQARAAVDTYCRHNYG-VVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFLNGQEEKAGMVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWR-ARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q30154-1", "uniprot_id": "DRB5_HUMAN", "id": "Q30154-1", "name": "HLA class II histocompatibility antigen, DR beta 5 chain", "aln": "---MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDIYNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYG-VGESFTVQRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWR-AQSESAQSKMLSGVGGFVLGLLFLGAGLFIYFKNQKGHSGLHPTGLVS----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P13762-1", "uniprot_id": "DRB4_HUMAN", "id": "P13762-1", "name": "HLA class II histocompatibility antigen, DR beta 4 chain", "aln": "---MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYIYNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYG-VVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWS-ARSESAQSKMLSGVGGFVLGLLFLGTGLFIYFRNQKGHSGLQPTGLLS----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P01921-1", "uniprot_id": "HB2D_MOUSE", "id": "P01921-1", "name": "H-2 class II histocompatibility antigen, A-D beta chain", "aln": "----MALQIP-SLLLSAAVVVLMVLSSPRTEGGNSERHFVVQFKGECYYTNGTQRIRLVTRYIYNREEYVRYDSDVGEYRAVTELGRPDAEYWNSQPEILERTRAEVDTACRHNYEGPETSTSLRRLEQPNVAISLSRTEALNHHNTLVCSVTDFYPAKIKVRWFRNGQEETVGVSSTQLIRNGDWTFQVLVMLEMTPHQGEVYTCHVEHPSLKSPITVEWR-AQSESARSKMLSGIGGCVLGVIFLGLGLFIRHRSQKGPRGPPPAGLLQ----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29826-1", "uniprot_id": "HB2B_RAT", "id": "P29826-1", "name": "Rano class II histocompatibility antigen, B-1 beta chain", "aln": "----MALQTP-SFLLPAAVVVLMVLSSPGTEGRDSPRDFVYQFKGLCYYTNGTQRIRDVIRYIYNQEEYLRYDSDVGEYRALTELGRPSAEYFNKQ--YLEQTRAELDTVCRHNYEGSEVRTSLRRLEQPNVAISLSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTQLIRNGDWTFQILVMLEMTPQRGEVYICHVDHPSLESPVTVEWR-AQSESAQSKMLSGIGGFVLGVIFLGLGLFIRHKRQKGPRGPPPAGLLQ----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06341-1", "uniprot_id": "HB2A_RAT", "id": "P06341-1", "name": "Rano class II histocompatibility antigen, A beta chain", "aln": "-------------------------------------DFVYQFKGLCYYTNGTQRIRSVDRRFYNQEEFLRYDSDVGEFRALTELGRSWADDWNSQKEILEQKRAEMDTVCRYNYEETEVPTSLRRLERPNVAISLSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETTGVVSTQLIKNGDWTFQILVMLEMTPQRGDVYTCHVDHASLESPVTVEWR-AQSESAQSKMLSGIGGLVLGVIFLGLGLFIRHKRQKGPQGPPPAGLLQ----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P01920-1", "uniprot_id": "DQB1_HUMAN", "id": "P01920-1", "name": "HLA class II histocompatibility antigen, DQ beta 1 chain", "aln": "MSWKKALRIPGGLRAATVTLMLAMLSTPVAEGRDSPEDFVYQFKAMCYFTNGTERVRYVTRYIYNREEYARFDSDVEVYRAVTPLGPPDAEYWNSQKEVLERTRAELDTVCRHNYQ-LELRTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWTFQILVMLEMTPQHGDVYTCHVEHPSLQNPITVEWR-AQSESAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQKG--------LLH----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05538-1", "uniprot_id": "DQB2_HUMAN", "id": "P05538-1", "name": "HLA class II histocompatibility antigen, DQ beta 2 chain", "aln": "MSWKMALQIPGGFWAAAVTVMLVMLSTPVAEARDFPKDFLVQFKGMCYFTNGTERVRGVARYIYNREEYGRFDSDVGEFQAVTELG-RSIEDWNNYKDFLEQERAAVDKVCRHNYE-AELRTTLQRQVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTSLIRNGDWTFQILVMLEITPQRGDIYTCQVEHPSLQSPITVEWR-AQSESAQSKMLSGIGGFVLGLIFLGLGLIIRHRGQKGPRGPPPAGLLH----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZVP9-1", "uniprot_id": "A0A8I5ZVP9_RAT", "id": "A0A8I5ZVP9-1", "name": "", "aln": "------MGAGRAPWVVALLVNLMRPDSFMVEGRDSPEDFVIQAKAECYFTNGTEKVRFLVRFIFNLEEYLHFDSDLGFFVALTELGEVDADQWNKRLDLLETSRAAVNMVCRQEYK-LGAPFTVERNVPPEVTVYPERTPLLQQHNLLLCSVTDFYPGDISVRWFRNGQEERSGVMSTGLVRNGDWTFQTTVMLEMIPELGDVYSCLVEHPGLLRPVSVAWV-AQSEYSWEKILSGAAAFLLGLTVFLVGAVIHLKAQKGGSRQVLSLRAPPGKPHLMLTGDLILSFQRPWRLSLAMRLQGRFSHLTPTKILMEASPPEPEEV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35424-1", "uniprot_id": "O35424_MOUSE", "id": "O35424-1", "name": "", "aln": "------MGAGRAPWVVALLVNLMRLDSFMIEGRDSPENFVIQAKADCYFTNGTEKVHLLVRFIFNLEEYLHFDSDLGMFVALTELGEPDADQWNKRLDLLETSRAAVNMVCRQKYK-LGAPFTVERNVPPEVTVYPERTPLLQQHNLLLCSVTGFYPGDISVKWFRNGQEERSGVMSTGLVRNGDWTFQTTVMLEMIPELGDIYSCLVEHPGLLRPVSVAWM-AQSEYSWKKILSGAAVFLLGLIVFLVGVVIHLKAQKA------SVETQPGN--------------------------------EASRESLHSQP------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13765-1", "uniprot_id": "DOB_HUMAN", "id": "P13765-1", "name": "HLA class II histocompatibility antigen, DO beta chain", "aln": "------MGSGWVPWVVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDSDVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYR-LGAPFTVGRKVQPEVTVYPERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLEMTPELGHVYTCLVDHSSLLSPVSVEWR-AQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLRAQKG------YVRTQMSGN-------------------------------EVSRAVLLPQSC-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B5P7-1", "uniprot_id": "A0A8M2B5P7_DANRE", "id": "A0A8M2B5P7-1", "name": "", "aln": "-------------MFNVLVIRLALLLPFLLETAHGHYGFVQFT---CHMLGSLQNVEVTYSIYFDTTELLRFNSTENKAVAYTEYAMKWANDLNKQPKWLHEQVEKNIADCKLFGE--TYFPLVAKTVKPEVFVRSLREASGKRPALLSCSAYNFYPKHIKLTWMRDDKVVTADVMSTKVMADGDWYYQIHSHLEYFPQPGEKISCVVEHASSHKPMIYYWDSFLTESNKNKIITGAAGIVLGAIMAAGGLIYYKRKHTVGNTSAGSQYIGCSEPLQTLSE------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: *: .. .: * :::* * * . : *. :. *: : : * * : : :: * * . .*** *.: *: :.: .: ** : :*** :* ** *. *. . . . : :: * ::* :** . * . : ", "identical_positions": 31, "similar_positions": 49, "identity": "9.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010122-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55075-1", "uniprot_id": "FGF8_HUMAN", "id": "P55075-1", "name": "Fibroblast growth factor 8", "aln": "MGSPRSALSCLLLHLLVLCLQAQ----------------------------------------------------------------EGPGRGPALGRELASLFRAGREPQGVSQQHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZL19-1", "uniprot_id": "A0A8I5ZL19_RAT", "id": "A0A8I5ZL19-1", "name": "Fibroblast growth factor", "aln": "MGSPRSALSCLLLHLLVLCLQAQVRSAAQKRGPGAGDPADTLGQGHEDRSFGQRSRAGKNFTNPAPNYPEEGSKEQRDSVLPKVTEREGPGGGPALGREPASLLRAGREPQGVSQQHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P37237-1", "uniprot_id": "FGF8_MOUSE", "id": "P37237-1", "name": "Fibroblast growth factor 8", "aln": "MGSPRSALSCLLLHLLVLCLQAQVRSAAQKRGPGAGNPADTLGQGHEDRPFGQRSRAG----------------------------KNFTNPAPNYPEEGSKEQRDSVLPK-VTQRHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q805B2-1", "uniprot_id": "FGF8B_DANRE", "id": "Q805B2-1", "name": "Fibroblast growth factor 8b", "aln": "MRLKSSRLGYLFLQFMTLCFYTQ------------------------------------------------------------------------------MTMQSISMPN--FKHHVTEQSRLSDRMSRRLTRTYQLYSRTSGKHVQVLGNKRVNANAEDGDIHAKLVVETDTFGSRVRIRGAKTGYYICMNKKGKLIGRRKGRGKDCIFTEIVLENNYTALQNAKYKGWYMAFTRKGRPRKAMQTRQHQREAHFMKRLPRGHLLTEQKP-FDLIPYP-LNKRTKHHQRASVN---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * *. *:*:::.**: :* : *: ::** *** ::*::**** *****************.***:** ***** .***:***********:***:** ***********.: :*:****:******************:**************. :*******.********** ***. *::: ** :.: : **: . ", "identical_positions": 138, "similar_positions": 41, "identity": "46.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010125-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35372-1", "uniprot_id": "OPRM_HUMAN", "id": "P35372-1", "name": "Mu-type opioid receptor", "aln": "MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTK---YRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P42866-1", "uniprot_id": "OPRM_MOUSE", "id": "P42866-1", "name": "Mu-type opioid receptor", "aln": "MDSSAGPGNISDCSDPLAPASCSPAP--GSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTK---YRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B8JHS2-1", "uniprot_id": "B8JHS2_DANRE", "id": "B8JHS2-1", "name": "Mu-type opioid receptor", "aln": "MMENTG--NISDLLYALSNPMVSNSS--IFCRNFSNSSGLVN-----MNSSVCDRTPELDKSSTP-VIVAIIITALYSIVCVMGLVGNVLVMYVIIRYTKMKTATNIYIFNLALADSLATSTLPFQSVNYLMGTWPFGDELCKIVMSIDYYNMFTSIFTLTTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMVMASTTSDLHSNGIIDCTLLFPHPSWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIFVIIKALVTIPNSLLQTITWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCVPSPSVLDLQNSTRSRNPQRDGQSSGHTVDRTNQQV-----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ..:. * *: .*: . * :. *:*: .* . .:.: . . :.:* ::.** * ********:**.**.******:********************:********************* *****:************** ***************************:****************.**:*. : :* ***** *.**:*************************************************************************:******:***:: :**::**********************************:*:.* :: ***:* *: *: *:.:******:*: ", "identical_positions": 279, "similar_positions": 60, "identity": "69.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010126-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63604-1", "uniprot_id": "NTRK2_RAT", "id": "Q63604-1", "name": "BDNF/NT-3 growth factors receptor", "aln": "MSPWPRWHGPAMARLWGLCLLVLGFWRASLACPMSCKCSTTRIWCTEPSPGIVAFPRLEPNSIDPENITEILIANQKRLEIINEDDVEAYVGLKNLTIVDSGLKFVAYKAFLKNGNLRHINFTRNKLTSLSRRHFRHLDLSDLILTGNPFTCSCDIMWLKTLQETKSSPDTQDLYCLNESSKNTPLANLQIPNCGLPSARLAAPNLTVEEGKSVTISCSVGGDPLPTLYWDVGNLVSKHMNETS--HTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCIPFTVRGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLMAKNEYGKDERQISAHFMGRPGVDYETNPNYPEVLYEDWTTPT-DIGDTTNKSNEIPSTDVADQTNREHLSVYAVVVIASVVGFCLLVMLLLLKLARHSKFGMKGPASVISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEG--NPPTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQEVYELMLGCWQREPHTRKNIKNIHTLLQNLAKASPVYLDILG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15209-1", "uniprot_id": "NTRK2_MOUSE", "id": "P15209-1", "name": "BDNF/NT-3 growth factors receptor", "aln": "MSPWLKWHGPAMARLWGLCLLVLGFWRASLACPTSCKCSSARIWCTEPSPGIVAFPRLEPNSVDPENITEILIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAYKAFLKNSNLRHINFTRNKLTSLSRRHFRHLDLSDLILTGNPFTCSCDIMWLKTLQETKSSPDTQDLYCLNESSKNMPLANLQIPNCGLPSARLAAPNLTVEEGKSVTLSCSVGGDPLPTLYWDVGNLVSKHMNETS--HTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCIPFTVRGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLMAKNEYGKDERQISAHFMGRPGVDYETNPNYPEVLYEDWTTPT-DIGDTTNKSNEIPSTDVADQSNREHLSVYAVVVIASVVGFCLLVMLLLLKLARHSKFGMKGPASVISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEG--NPPTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQEVYELMLGCWQREPHTRKNIKSIHTLLQNLAKASPVYLDILG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16620-1", "uniprot_id": "NTRK2_HUMAN", "id": "Q16620-1", "name": "BDNF/NT-3 growth factors receptor", "aln": "MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEPNSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHINFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETS--HTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPSTDVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEG--NPPTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPVYLDILG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A3P4-1", "uniprot_id": "A0AB13A3P4_DANRE", "id": "A0AB13A3P4-1", "name": "Tyrosine-protein kinase receptor", "aln": "MSFGMTGCG------FGWAVMLLALWRPATACPELCTCTGLRISCVDAERSIMAFPKLES-EADMENVTDIYIANQISFTSINERDLEFYRSLRNLTVINTKLAYIARLAFQSNPKLQYLNLKENNLSKLSWRTFRHLNISYLLLAGNPLQCLCDNMWLKQWRVEEA----EELLCVEEGGKRRALATLTLPDCVLPTVTLTPTNVTMKKGLNVTLTCNTSGMPTPNLTWTTCKLNSAFKEEGSGQISRSQLKLTNVSSLDNKCRITCRSDNMVGESEASVELDILFPPVISKLTDAIPDHHWCIPFSVSGNPKPKLRWLLDEQPIQEGKFIHTMIHDYSEGEYHGCLQLDSPTHINNGMYTLLARNQFGEDSKAVSAHFMHEP-------WNVSEPLYYDATTDDTPLGPPEDK-----------------VAVYVVVGIAAITFTGFVLMLVILKFGRNSKFGIKGPSSVISNDDDSASPLHHVSNGSNTPSSSDMNADAVIIGMTKIPVIENPQYFRSTSSLLKSDTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLSADQEKILVAVKTLKEASENARKDFHREAELLTNLQHEHIVTFYGVCVESDPLIMVFEYMMHGDLNKFLRAHGPDAVLMSDGQIQQQAELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPKEVYDLMLGCWQREPHTRLNIKEIHNLLLNLAKASPVYLDILG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * :* . :::.:**.: *** *.*: ** * :.. .*:***:**. . * **:*:* **** : *** *:* * .*:***:::: * ::* ** .* :*:::*:..*:*:.** : ****::* *:*.***: * ** **:* : :: ::* *::*..*. .**.* :*:* **:. *:..*:*:::* .:*::*...* * *.: * . :* * . :* * ::..*::**:** *. :*:* ::*:***.: **:* : *.*.*: * .. .********:* ***** *:*: : ::*.*:* * ** .. *********.***:*** ***:*:*::*:*.: :***** * * .: :* * * :* . :: ::**.** **::. :::**.:**:.*:****:***:***************:**********: ..******************* *.* **.**********************************..:*:**********:**:**********************.*******.********** ******************::* : :*************************************************************************************************************************************:***:*********** * *** **.** **************", "identical_positions": 505, "similar_positions": 172, "identity": "61.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010126-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q16620-1", "uniprot_id": "NTRK2_HUMAN", "id": "Q16620-1", "name": "BDNF/NT-3 growth factors receptor", "aln": "MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEPNSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHINFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGN-----LVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPSTDVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNP--PTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPVYLDILG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ILA2-1", "uniprot_id": "A0A0R4ILA2_DANRE", "id": "A0A0R4ILA2-1", "name": "Tyrosine-protein kinase receptor", "aln": "MTAGVRG-----MACWGLCGFLFGLLRISSACPVSCFCNASRISCIDQEPGIEDFPVLMPES-DMENITDIYISNQKRLFTINEDHMKFYSNLRNLTVTNTHLTYVSTMAFFNNSKLQYLNLGDNNLSTLSWMAMRNSNVSTLLLSGNPLQCACENIWIKLWLDD---SERDVLQCLQEGGKAKTLSRLTLPLCEHPRVEVFPTDVSQMAGSDATVICNASGSPTPELTWTLNSSEHPPLSTSHEISKMDLQSVLTLNGLSPNDNGRKLICSAENIVGQIEATVMLNISFPPTVLELYLPERSQDWCIPFVVTGNPRPDLHWYHEGKPLEEQEYIRTEIHDITNTEYHGCLKLDTPTHIHNGIYTLVASNEFGEDRGNVTAHFMRIPDVDHSG---IEGVFYYDT-TVSPDIPPLEDR-----------------VAVYIVVGIAGVALTGCILMLVFLKYGRSSKFGMKGSSSVISNDDDSASPLHHVSNGNNTPSSSEMGPDAVIIGMTKIPVIENPQYFRNPGSMLKSDTLVQHIKRHNILLKRELGEGAFGKVFLAECYNLSPDQEKILVAVKTLKEASESGRADFHREAELLTNLQHEHIVKFYGVCVESDPLIMVFEYMKHGDLNKFLRAHGPDAVLMADGQQSLLVELTQPQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRRFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPKEVYDLMLGCWQREPYMRLNIKEIHNLLQSLAKASPVYLDILG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: :* **:* ::.*: * : ***.** *.**** * * .*** ** * *:* * ****:*:*:***** ****.:: * .*****:.:: *.:*: **::**:**::*: *:*::** :*: ::* *:* ***: *:*: :*** : .: : * **:*..* .*:.* :* * * .:: ..::: *.. *: *..:*.*.*:: * :.. * :.* .. . *. * :..:*.:*.*::: * ***:**: : :* *.: *.**: * * .:.*****.*.***:* *:*:::* *:*.:** *:** .:*******:**.***::** ***:*.**:*:*. :::**** *.:*... .*:* * *.: ** :* ::** ** **.*. ::**.:** .* *******.:***************:***.******* ********************* ..* **.**:*********:*********************.*:*:**********:**:..* **************************.******************************:*: .****.*****************************************************************************:**************************************************:***:**********:** *** **.***.*************", "identical_positions": 505, "similar_positions": 175, "identity": "60.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010126-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q16288-1", "uniprot_id": "NTRK3_HUMAN", "id": "Q16288-1", "name": "NT-3 growth factor receptor", "aln": "MDVSLCPAKCSFWRIFLLGSVWLDYVGSVLACPANCVCSKTEINCRRPDDGNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRSLHTLNAVDMELYTGLQKLTIKNSGLRSIQPRAFAKNPHLRYINLSSNRLTTLSWQLFQTLSLRELQLEQNFFNCSCDIRWMQLWQEQGEAKLNSQNLYCINADGSQLPLFRMNISQCDLPEISVSHVNLTVREGDNAVITCNGSGSPLPDVDWIVTGLQSINTHQTNLNWTNVHAINLTLVNVTSEDNGFTLTCIAENVVGMSNASVALTVYYPPRVVSLEEPELRLEHCIEFVVRGNPPPTLHWLHNGQPLRESKIIHVEYYQEGEISEGCLLFNKPTHYNNGNYTLIAKNPLGTANQTINGHFLKEPFPESTDNFILFDEVSPTPPITVTHKPEEDTFGVSIAVGLAAFACVLLVVLFVMINKYGRRSKFGMKGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHALGKATPIYLDILG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QKJ0-1", "uniprot_id": "F1QKJ0_DANRE", "id": "F1QKJ0-1", "name": "Tyrosine-protein kinase receptor", "aln": "MDLFSIPPRVCLWRILFLLSIFQDYMSSMLDCPPTCTCSTTDIFCNKSYQGNFFPLLALQDT-VSDGNTTNSLPDLFENISTIHIENW-SLQTLKDLDMELYTGLQRLNIVNCNLRTIQSRAFAKNPHLRYINLSRNPLTTLSWQLFQNLQLLELKLEGVVFNCSCNIRWIQLWQQRGEAGLHNQQLFCFNG-YSKIPLQLMNISQCDFPEISVSHSNLTVTEGDRVMITCNGSGIPVPEVDWTVGGLHSINTHQANQYPPNVHSINLTLVNVSRDDNGFMLTCIAENIVGMTNASIQLSVQFPPAIINFEEPQKRHDTCMMFTVRANPLPTLHWSFKGEEIKATEYVHPEMEVYQDNLEGCLLFKNPTQHNNGNYTLEARNYLGVAVKTVYAHFLHPPFEDYPD----YVSPTPTAIPTMTHRPEEDTFGVSIAVGLAGFACVLLVVMFVLINKYGRRSKFGMKGPVAVISGEEDSASPLHHVNHGIITPCTLDAGPDAVVIGMTRIPVIENPQYFRHGHNCNKPATYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKTLKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCVDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPLQTNGELGLSQMLHIASQIASGMVYLGSQHFVHRDLATRNCLVGNGLLVKIGDFGMSRDIYSTDYYR--------------VGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLANNEVIECITQGRVLERPRLCPKEVYDIMLGCWQREPQQRLNIKDIQKILFALGKATPVYLDILG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: *.: .:***::* *:: **:.*:* **..*.**.*:* *.:. :**:**** **: *:**:: .:.*: .**::****** **:**: :*********:*.* *..**:**.*************** * **********.*.* **:** .*****:***:****::*** *:.*:*:*:*. *::** *******:******* **** ***..:******* *:*:*** * **:******:* .***:********: :**** *******:***:***: *:* :** ::.:***: * : *: *.**.** ***** .:*: :: :: :* * : ******::**::******* *:* **.* :*: .***: ** : .* : . :**. *:**:***************.********:**:*******************************:**** **.:******:******************:****:** *********************************************:********************************** ************************************ *::**********************.***************** .*************:******* *************************************************:*.****************:*******:****************:* ***.*******:******", "identical_positions": 613, "similar_positions": 133, "identity": "73.06%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010126-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q03351-1", "uniprot_id": "NTRK3_RAT", "id": "Q03351-1", "name": "NT-3 growth factor receptor", "aln": "MDVSLCPAKCSF-WRIFLLGSVWLDYVGSVLACPANCVCSKTEINCRRPDDGNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRGLHTLNAVDMELYTGLQKLTIKNSGLRNIQPRAFAKNPHLRYINLSSNRLTTLSWQLFQTLSLRELRLEQNFFNCSCDIRWMQLWQEQGEARLDSQSLYCISADGSQLPLFRMNISQCDLPEISVSHVNLTVREGDNAVITCNGSGSPLPDVDWIVTGLQSINTHQTNLNWTNVHAINLTLVNVTSEDNGFTLTCIAENVVGMSNASVALTVYYPPRVVSLVEPEVRLEHCIEFVVRGNPTPTLHWLYNGQPLRESKIIHMDYYQEGEVSEGCLLFNKPTHYNNGNYTLIAKNALGTANQTINGHFLKEPFPESTDFFDFESDASPTPPITVTHKPEEDTFGVSIAVGLAAFACVLLVVLFIMINKYGRRSKFGMKGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYREGPYQKGPFSVSWQQQRLAASAASTLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHALGKATPIYLDILG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6VNS1-1", "uniprot_id": "NTRK3_MOUSE", "id": "Q6VNS1-1", "name": "NT-3 growth factor receptor", "aln": "MDVSLCPAKCSF-WRIFLLGSVWLDYVGSVLACPANCVCSKTEINCRRPDDGNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRGLHTLNAVDMELYTGLQKLTIKNSGLRNIQPRAFAKNPHLRYINLSSNRLTTLSWQLFQTLSLRELRLEQNFFNCSCDIRWMQLWQEQGEARLDSQSLYCISADGSQLPLFRMNISQCDLPEISVSHVNLTVREGDNAVITCNGSGSPLPDVDWIVTGLQSINTHQTNLNWTNVHAINLTLVNVTSEDNGFTLTCIAENVVGMSNASVALTVYYPPRVVSLVEPEVRLEHCIEFVVRGNPTPTLHWLYNGQPLRESKIIHMDYYQEGEVSEGCLLFNKPTHYNNGNYTLIAKNALGTANQTINGHFLKEPFPESTDFFDFESDASPTPPITVTHKPEEDTFGVSIAVGLAAFACVLLVVLFIMINKYGRRSKFGMKGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYR---------------------------------------VGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHALGKATPIYLDILG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16288-1", "uniprot_id": "NTRK3_HUMAN", "id": "Q16288-1", "name": "NT-3 growth factor receptor", "aln": "MDVSLCPAKCSF-WRIFLLGSVWLDYVGSVLACPANCVCSKTEINCRRPDDGNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRSLHTLNAVDMELYTGLQKLTIKNSGLRSIQPRAFAKNPHLRYINLSSNRLTTLSWQLFQTLSLRELQLEQNFFNCSCDIRWMQLWQEQGEAKLNSQNLYCINADGSQLPLFRMNISQCDLPEISVSHVNLTVREGDNAVITCNGSGSPLPDVDWIVTGLQSINTHQTNLNWTNVHAINLTLVNVTSEDNGFTLTCIAENVVGMSNASVALTVYYPPRVVSLEEPELRLEHCIEFVVRGNPPPTLHWLHNGQPLRESKIIHVEYYQEGEISEGCLLFNKPTHYNNGNYTLIAKNPLGTANQTINGHFLKEPFPESTDNFILFDEVSPTPPITVTHKPEEDTFGVSIAVGLAAFACVLLVVLFVMINKYGRRSKFGMKGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYR-------------------------LFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHALGKATPIYLDILG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RHB8-1", "uniprot_id": "A0A8M1RHB8_DANRE", "id": "A0A8M1RHB8-1", "name": "Tyrosine-protein kinase receptor", "aln": "MDVWLCSAVPVFTWRLFFLSSIFQGYWSSMLDCPPTCSCSPTEIYCNKSDVGNFFPLLALQESAG-NGSNNNDIEELFRNITSIHIENWTGLQILRDVDMELYTGLQRLTIINCNLRQIQPRAFSRNPHLRYINLSRNPLASLSWQLFQHLQLVELRLEGVVFDCGCKIRWIQLWRLRGEAGLHTQQLYCKDG-ASKISLRSMSIAHCDLQDISVAHSNLTVLEGGNVTLSCNGSGSPVPEVDWAVKGLHSINTHQSTVYLPNTHSINLTLVNVSRDDNGFVLTCISENVVGMNNVSLQLSVLFPPVILKLDEPERRHHTCIEFTVRGFPHPTLHWFYKGREILQSEYIRMEMDYYKDYLEGCLTFENPTHYDNGNYTLVATNSLGSVSKTVFGHFLDPPFMEDDGIMEY------TPPPEDEGKRPEDSFGMSIAVGLAGFGCVFLIVIFVLINKYSRRNKFGIKGPVAVISGEEDSASPLHHVNHGIVTPCSLDAGPDAVVIGMSRIPVIENPQYFRHGHNCNKPTTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKTLKDPTLTARKDFQREAELLTNLQHEHIVKFYGVCVDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPMQSNGELGLSQMLHIATQIAAGMVYLSSQHFVHRDLATRNCLVGNGLLVKIGDFGMSRDIYSSDYYR---------------------------------------VGGHTMLPIRWMPPESIMYRKFSTESDVWSFGVIMWEIFTYGKQPWFHLSNNEVIECITQGRVLDRPRLCPKEVYDLMLGCWQREPQQRLNIKDIQKVLYALGKATPVYLDILG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** **.* * **:*:*.*:: .* .*:* **..* ** *** *.:.* **:**** *:*.. **. . :* :: *********** .*: *. **********:*** *..**.******::********** * *::******* *.* **:** .*:*.*.***:***: :*** *.:*.*** .. .*::.* *.*::*** :***:* **** **.*..::*******:*:*** *.**:******:.: .*.*:********: :****.****:******.*.*: *:* :** ::.* *** * . ****.*** * *****:::*: : :*: *::: : **** *::****:******:*.*.**:..:*: ****. ** *. . : *** * **:**:*******.*.**:*:*:*::****.**.***:*******************:****.**.*******:*****:************:****:** *********************************************:******:*************************** ************************************ *::************:***:*****:***************** .*************:**:**** **********************:***********:************:***.************:***:*******:****************:* *:*:*******:******", "identical_positions": 587, "similar_positions": 152, "identity": "67.86%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010130-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q13363-1", "uniprot_id": "CTBP1_HUMAN", "id": "Q13363-1", "name": "C-terminal-binding protein 1", "aln": "---MGSSHLLNKGLP---LGVRPPIMNGPLHPRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRATWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGVERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKNCVNKDHLTAATHWASMD--PAVVHPE--LNGAAY-RYPPG------VVGVAPTGIP-------------AAVEGIVPSAMS---------LSHGLPPVAHPPHAPSPGQTVKPEADRDHASDQL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88712-1", "uniprot_id": "CTBP1_MOUSE", "id": "O88712-1", "name": "C-terminal-binding protein 1", "aln": "---MGSSHLLNKGLP---LGVRPPIMNGPMHPRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRTTWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGIERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKNCVNKDHLTAATHWASMD--PAVVHPE--LNGAAYSRYPPG------VVSVAPTGIP-------------AAVEGIVPSAMS---------LSHGLPPVAHPPHAPSPGQTVKPEADRDHTSDQL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PBY6-1", "uniprot_id": "A0A8M1PBY6_DANRE", "id": "A0A8M1PBY6-1", "name": "", "aln": "MALMDKHKVKRQRLDRICEGIRPPILNGPMHPRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVAALLYHTITLSRDDLDKFKGLRVIVRIGSGFDNVDIKAAAELGIAVCNVPAASVEETADTAMCLILNLYRRVTWMHQALREGTRASSVEQIREVAGGAARIRGETLGIIGLGRVGQAVALRAKAFGFGVIFYDPYLPDGVERSLGLQRMATLQDLLMHSDCVSLHCSLNEHNHHLINDFTIKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHETEPFSFSQGPLKDAPNLICTPHTSWYSEQASIEAREEAAREVRRAITGRIPDSLKNCVNKEYLMAASQWPSME--ATTVHSE--LNGAAAYRFPAG------LIGVAAGGLPG----------AGAGVEGIVAGSLP---------LAHAIAPVSHPPHTPSPGQPSKAEADRDIPSDQ----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O46036-1", "uniprot_id": "CTBP_DROME", "id": "O46036-1", "name": "C-terminal-binding protein", "aln": "---MDKNLMMPKRSR---IDVKGNFANGPLQARPLVALLDGRDCSIEMPILKDVATVAFCDAQSTSEIHEKVLNEAVGALMWHTIILTKEDLEKFKALRIIVRIGSGTDNIDVKAAGELGIAVCNVPGYGVEEVADTTMCLILNLYRRTYWLANMVREGKKFTGPEQVREAAHGCARIRGDTLGLVGLGRIGSAVALRAKAFGFNVIFYDPYLPDGIDKSLGLTRVYTLQDLLFQSDCVSLHCTLNEHNHHLINEFTIKQMRPGAFLVNTARGGLVDDETLALALKQGRIRAAALDVHENEPYNVFQGALKDAPNLICTPHAAFFSDASATELREMAATEIRRAIVGNIPDVLRNCVNKEYFMRTPPAAAAGGVAAAVYPEGALHHRAHSTTPHDGPHSTTNLGSTVGGGPTTVAQAAAAAVAAAAAAALLPSPVPSHLSPQVGGLPLGIVSSQSPLSAPDPNNHLSSSIKTEVKAESTEAP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. : : .:: : ***::.************::*******************.***********.**::*** *:::**:***.**:******* **:*:*:*.:*********. .***.**:::* *******. *: : :***.: . **:**.* *.*****:***::****:*.***********.*:******.**::::*** *: ******::****:*** **********:**:**** **************:::** ***:****.*******.**:.. **.************::::*: :: * ** ** *:****.*.*** *:*****::: :. .: .:.*:.* *: * * . :. : * * *.. .::...:. *. .: . * :*.*.: ... . : ::. ", "identical_positions": 248, "similar_positions": 126, "identity": "51.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010130-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P56545-1", "uniprot_id": "CTBP2_HUMAN", "id": "P56545-1", "name": "C-terminal-binding protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALVDKHKVKRQ-------RLDRICEGIRPQIMNGPLHPRPLVALLDGRDCTVEMPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPESLRNCVNKEFFVTSAPWS--------VIDQQAIHPELNGATYRYPPG---IVGVAPGG-------------LPAAMEGIIPGGIPVTHN---------LPTVAHPSQAPSPNQPTKHGDNREHPNEQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56546-1", "uniprot_id": "CTBP2_MOUSE", "id": "P56546-1", "name": "C-terminal-binding protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALVDKHKVKRQ-------RLDRICEGIRPQIMNGPLHPRPLVALLDGRDCTVEMPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTVCHILNLYRRNTWLYQALREGTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPESLRNCVNKEFFVTSAPWS--------VIDQQAIHPELNGATYRYPPG---IVGVAPGG-------------LPPAMEGIIPGGIPVTHN---------LPTVAHPSQAPSPNQPTKHGDNREHPNEQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9EQH5-1", "uniprot_id": "CTBP2_RAT", "id": "Q9EQH5-1", "name": "C-terminal-binding protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALVDKHKVKRQ-------RLDRICEGIRPQIMNGPLHPRPLVALLDGRDCTVEMPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTVCHILNLYRRNTWLYQALREGTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPESLRNCVNKEFFVTSTPWS--------VIDQQAIHPELNGATYRYPPG---IVGVAPGG-------------LPPAMEGIIPGGIPVTHN---------LPTVAHPSQAPSPNQPTKHGDNREHPNEQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AB32T658-1", "uniprot_id": "A0AB32T658_DANRE", "id": "A0AB32T658-1", "name": "C-terminal-binding protein 2", "aln": "MVSSFLLPSPPAVFPRLIIQRSPSERSHLIARPFHCDRDGTQKLLLDLSKQLPIGRSQSWDTLGGNEGHWERSDSVYEQQARMAGRRNSLSYGADAGGGWYEPAPGVRPPDLDLKREPEAYQESLYNQGYLDRPDPRNIRKSSVPELNSHYDRPPIAHRGTMPPHDYYQQDPGMPSRPTEGFYRGEQPHSLNRSSSHYGMMAGPRQIWEQGSGGRPGSVAPTPGVPPPPPPTVHDMGRIYRDPMLSGPLPATPGTKMMHEGQRIPSRAQSPARYIMEPNSPRYAAEPPASLTSHTVYSDVNGRPIDPHQPTATCLVVDPVAQGMDGTSRGMVMHPENPSPYTIQQQQQAQQQQQMQQQIQQQQMQQVQPVQQMQQVQPVQQMQQVQPVQQMQQAQPVQQMQQAQPVQQMQPVQPVQQMQPVQQVQQVPQVQPVQQVPHVQPVASPNPIYTPVPPVAPAPVTTPGVAVIPAPLPQLPAQPLTAAPPPSVPQTPVAPVDPKKNADPEFLALLHKEGLSESTINSLLQQGFDSTAMLAVMEENDVRSVAPNLGQARVLSRVVLCCKRPPEIVPATPLHPSAPARGRSNSFSHRSDIYVHQPPPLTPGLESQYIQPPSTPMQTMSPRIGDGYSRRPSSAPSQQLLETSGYPGPRVSGVYSGAMVPVQPRPLSGYNPHSGLPVTAMSQQVAIPAHLPGIQQQMAALPPQIHAMPLPALSAVPQSMTVPALAPQQAPKAYTTNYTVPMELMKRDRSLATMSPMPSPHLSPQVMRKAGVSSDGALVPIGGAVPGQNMNLANQKLSRRTGPPVIVSTMASPDTSIRPQIMNGPMHPRPLVALLDGRDCTVEMPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRIIIRIGSGYDNIDIKAAGEMGIAVCNIPSAAVEETADSTLCHILNLYRRNTWLYQAMREGTRVQSVEQIREVASGAARIRGETLGLIGFGRSGQAVAVRAKAFGFNVIFYDPYLQDGLERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFTQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPDSLRNCVNKEFFVTTAPWG--------VMEQQ-VHPELNGGAYRFPPG---AVGVSPGG-------------MGGQIEGMMPGGLPSAHP---------LPPGTQPSLAPSPTQLLKHNDHREHLAKS----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O46036-1", "uniprot_id": "CTBP_DROME", "id": "O46036-1", "name": "C-terminal-binding protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDKNLMMPK----------RSRIDVKGNFANGPLQARPLVALLDGRDCSIEMPILKDVATVAFCDAQSTSEIHEKVLNEAVGALMWHTIILTKEDLEKFKALRIIVRIGSGTDNIDVKAAGELGIAVCNVPGYGVEEVADTTMCLILNLYRRTYWLANMVREGKKFTGPEQVREAAHGCARIRGDTLGLVGLGRIGSAVALRAKAFGFNVIFYDPYLPDGIDKSLGLTRVYTLQDLLFQSDCVSLHCTLNEHNHHLINEFTIKQMRPGAFLVNTARGGLVDDETLALALKQGRIRAAALDVHENEPYNVFQGALKDAPNLICTPHAAFFSDASATELREMAATEIRRAIVGNIPDVLRNCVNKEYFMRTPPAAAAGGVAAAVYPEGALHHRAHSTTPHDGPHSTTNLGSTVGGGPTTVAQAAAAAVAAAAAAALLPSPVPSHLSPQVGGLPLGIVSSQSPLSAPDPNNHLSSSIKTEVKAESTEAP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: .:: :: ***::.************::*******:***********.*************:*:*** **:**********:*:***** **:*:*****:******:*. .***.**:*:* *******. ** : :***.:. . **:**.* *.*****:****:*:** *.***:*******.******** **:::***: *********:*********.**********:******* ******:*******:::** ***:****.*******.**:.. **.************:*::*: :: *:** *********.*.**: ********:*: :.* . * : :* . :. : : * :* : ** .::*. :* : . * **.*.: . . : * :. ", "identical_positions": 264, "similar_positions": 102, "identity": "20.66%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010131-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6MGC5-1", "uniprot_id": "Q6MGC5_RAT", "id": "Q6MGC5-1", "name": "", "aln": "---------------------------------------------------------------------------------------------MLPRPLR---LLLDTNPPGGVVLSSFRSRDPEEGGDPGGRAVGGGQEEEEEEEEEAS---------------------------------------------VSIWDEEEDGATFTVTSRQYRPLDPSAPLPPPR------------SSRRLRAGTLEALVRHLLDARTSGADMTFTPALLATHRAFTSTPALFGLVADRLEALES--------------------HPPGELERTTGVAIS-VLSTWLASHPEDFG-----------------SEVKG-QLDRLESFLLRTGYAAREGVVG--------GSADLIRNLRARVDPR----------------APDLPK-PLALPDDSPADPTDVLVFLADHLAEQLTLLDAELFLSLIPSQCLGGLWGHRDRPGHSHLCPSVRATVTQFNKVAGAVVSSVLGATPTGEGPREVTVRPLRPPQRARLLEKWIRVAEECRLLRNFSSVYAVVSALQSSPIHRLRAAWGETTRDSLRIFSSLCQIFSEEDNYSQSRELLMQEVKLQPP-VEPHSKKAPRS-------GSRGGGVVPYLGTFLKDLVMLDAASKDELEV-SVCVCVPPSQEFAVLSELLRLQNECRGYDLRPNPDIQQWLQGLQPLTEAQSHRVSCEVEPSGTIDSPAARTLRPALVITQWTEVLGSVGGPTPLVSWDRPTVGG-----DEVPGTPAPLLTRLAQHMKWPSVSSLDSALESSPSLHSPADPGHLSPPASSPRPSRGHRRSASCGSPLSGGTGEGASRSAGCGGGVSGPGSSDCRIIRVQMELGE----DGSVYKSILVTSQDKAPSVISRVLKKNNRDSAVASEFELVQLLPGDRELTIPHSANVFYAMDG-ASHDFLLRQRRRPSAATSGSHSGPSASGTPPSEGGGGSFPRIKATGRKIARALF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61193-1", "uniprot_id": "RGL2_MOUSE", "id": "Q61193-1", "name": "Ral guanine nucleotide dissociation stimulator-like 2", "aln": "---------------------------------------------------------------------------------------------MLPRPLR---LLLDTTPPGGVVLSSFRSRDPEEGGDPGGRAVGGGQEEEDEEEEEAS---------------------------------------------VSVWDEEEDGATFTVTSRQYRPLDPLAPLPPPR------------SSRRLRAGTLEALVRHLLDARTAGADMMFTPALLATHRAFTSTPALFGLVADRLEALES--------------------HPPGELERTTGVAIS-VLSTWLASHPEDFG-----------------SEVKG-QLDRLESFLLRTGYAAREGVVG--------GSADLIRNLRARVDPR----------------APDLPK-PLALPGDSPADPTDVLVFLADHLAEQLTLLDAELFLNLIPSQCLGGLWGHRDRPGHSHLCPSVRATVTQFNKVAGAVVSSVLGATSIGEGPREVTVRPLRPPQRARLLEKWIRVAEECRLLRNFSSVYAVVSALQSSPIHRLRAAWGETTRDSLRVFSSLCQIFSEEDNYSQSRELLMQEVKPQPP-VEPHSKKAPRS-------GFRGGGVVPYLGTFLKDLVMLDAASKDELEN-GYINFDKRRKEFAILSELLRLQKECRGYDLRPNSDIQQWLQGLQPLTEAQSHRVSCEVEPPGTSDSPAARTPRPTLVITQWTEVLGSVGGPTPLVSWDRPSVGG-----DEVPGTPAPLLTRLAQHMKWPSVSSLDSALESSPSLHSPADPGHLSPPASSPRPSRGHRRSASCGSPLSGNTGEGTSRSAGCGGGVSGPGSSDCRIIRVQMELGE----DGSVYKSILVTSQDKAPSVISRVLKKNNRDSAVASEFELVQLLPGDRELTIPHSANVFYAMDG-ASHDFLLRQRRRPSAATPGSHSGPSASGTPPSEGGGGSFPRIKATGRKIARALF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15211-1", "uniprot_id": "RGL2_HUMAN", "id": "O15211-1", "name": "Ral guanine nucleotide dissociation stimulator-like 2", "aln": "---------------------------------------------------------------------------------------------MLPRPLR---LLLDTSPPGGVVLSSFRSRDPEEGGGPGGLVVGGGQEEEEEEEEEAP---------------------------------------------VSVWDEEEDGAVFTVTSRQYRPLDPLVPMPPPR------------SSRRLRAGTLEALVRHLLDTRTSGTDVSFMSAFLATHRAFTSTPALLGLMADRLEALES--------------------HPTDELERTTEVAIS-VLSTWLASHPEDFG-----------------SEAKG-QLDRLESFLLQTGYAAGKGVGG--------GSADLIRNLRSRVDPQ----------------APDLPK-PLALPGDPPADPTDVLVFLADHLAEQLTLLDAELFLNLIPSQCLGGLWGHRDRPGHSHLCPSVRATVTQFNKVAGAVVSSVLGATSTGEGPGEVTIRPLRPPQRARLLEKWIRVAEECRLLRNFSSVYAVVSALQSSPIHRLRAAWGEATRDSLRVFSSLCQIFSEEDNYSQSRELLVQEVKLQSP-LEPHSKKAPRS-------GSRGGGVVPYLGTFLKDLVMLDAASKDELEN-GYINFDKRRKEFAVLSELRRLQNECRGYNLQPDHDIQRWLQGLRPLTEAQSHRVSCEVEPPGSSDPPAPRVLRPTLVISQWTEVLGSVGVPTPLVSCDRPSTGG-----DEAPTTPAPLLTRLAQHMKWPSVSSLDSALESSPSLHSPADPSHLSPPASSPRPSRGHRRSASCGSPLSGG-AEEASGGTGYGGEGSGPGASDCRIIRVQMELGE----DGSVYKSILVTSQDKAPSVISRVLKKNNRDSAVASEYELVQLLPGERELTIPASANVFYAMDG-ASHDFLLRQRRRSSTATPGVTSGPSASGTPPSEGGGGSFPRIKATGRKIARALF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B5A7-1", "uniprot_id": "A0A8M2B5A7_DANRE", "id": "A0A8M2B5A7-1", "name": "", "aln": "---------------------------------------------------------------------------------------------MIPRSMKSSGVDLPGVGPREVPLIGYRALQTELDGSPDQLWKESEHREADHHTQGEPSP--------------------------------MKTTWYCPLDLSTVSEMEEDGIIYTVVVKQG-PGSPTSPQSTAA------------RSQHVKAGTEEKLVLHLLHSFSMG-DSSFISIFLSTYRSFTSTQRVLDILICRLENPPG--------------------ESHSNSRQMFNKAVCTVFSTWMTDYPEDFR-----------------SLSDPSRLLRLAPLLPTDSSGAEIKSRL--------LRIAEELSEKTLLSAS----------------LSDPTKGLLSPPNPSDFDATSVLGFPSSVIAEQLTRIETDLFLKLVPHHCLGSLWSQRDKKGQEGACWSVRATIKQFNRLANAVTASCLWMT------------TLKSQQRARLLEKWISVAEACRTRKNFSSLYAILSALQSNPIHRLRKTWQETDREAVKRYEELSDIFSEKDNYSQSRELLKEEGTSKFANHDTKINNRRFT-------GSCAQGTVPYLGIFLRDLTMLDTAVKDRLEN-GFINFDKRRREFEVIAQIRLLQSSCKNSIFRTDETFIHWYHSVPTLREEESYKLSNQIEAPG--EPSPGRGLNPTVIITQCPDALSAVANTT------MDADGI-----FDFPSPVNQLLSKLCKHVKSPSVSCLD--VDSSPPSND-STPSILTTPTTAVKS---HRRSVSCGNNPTNSKPEAG---------------PDMRIVRIRMDLH-----DGNLYRSILVTSNDKTPTVISSALEKHNQNAQEASKYELIQLLPEGKELIIPPTGNVFYAMSS-ASVDFLLR-RRGGNTPTGSPNLGNETSAT---------FPRIKAKGRRLVRTLF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PCE9-1", "uniprot_id": "M9PCE9_DROME", "id": "M9PCE9-1", "name": "", "aln": "MNFTSRANCKCPHSQKHQQKPALIKSHTCAYQLQDLTGYNRALMPPLDNTDFSNAWRQVNNNTTSQSCAYHQQRQQQQQQQDAKDSKRHYHHHTCPRQRK---KSMTPVEPTHLCQKHQEAKQRRSRSASAKPRRNSSYHSYDDLDVSSAVLNAERKVVASLKYLCACTGATLRNLSKKTKDLHAKNYTYTKPTWRLWGEEHEKNAIFTVYLKKVRYHRPTPTASNDSDDEISHLEWETVRVRFVKAATLARLVEALATD-DGELESTFINVFLSTYRTFSTPKQVLSLLTQRYDALHEKHLEELEQAQQNGQVMDPAYDPHASIHEQHKKTLVSALHVWLDGFPEDWHEDNLQQILAFATKRLKRSDLHIKVLNRLERLIKQSLYGNGGGSGGSENNGHSWLSAARSQQMQQFMIPTHYGSSYDLTDQFNGMYLSPMGHGPIYRGPTHFLQAFRFPHVPVRHFAEQLTRMDTELFKRLIPHQCLGHTWARRDSGGSE----TVVATINQFNAVLFRVVSSILIDR-------------LKPQERALNISRWIDIAQELRMLKNFSSLKAIISALNSNSIYRLSKIWEVLPKERMEVFTELANICSEDNNAWTLREVLKREGTAKNPDPGSDHSDRHLQKLILNLGTQTSHGTIPYLGTFLTDLTMIHTANPDYLTENKLINFDKKRKEFEVLAQIKLLQGAANTYNLQADALFDHWFNSMPVFDEREAFELSCRLEPPPPAPRKSVVSTNTSLTNTTASSTASIMGHRKTDSIHSNSSSGAGSQFYCELNSSTSSRHNSLDRDVHHQHASLMSASSSVSNLSLDSSNSGGRQSGKLTHSQSMGNGLKSHGNGTTNGGSPHINAQLVQPSSG-TPHSAPDFYIIRVTYETDNIELDGIVLYKSIMLGNNERTPQVIRNAMLKLGLE-DDPDRFTLAQVLP-DKELVMPKNANVYYAVNTNYNLNFILRPRKEEGVAGSXSTAVP--------------LSQLWCLGYEGEE---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : : * : .: : . . . . .. :. . : .*.. :** :: * . . : ::*.* ** * : * :*:*:*:*::. ::.:: * : .. . .. :: .: .*: ..***: * . * ** :: . . : : . . : : :. . . :***** ::::** *:* :*** *.:** * . :* **:.*** : *.:* * *:. :** :.:** :*: * :****: *::***:*..*:** * :: :. : .*.:* **.:* **:* .* . : . .. .. . *.:**** ** **.*:.:* * * :** ::::: ** .. ::.: : :* :.: : * ::..:* .:*.. . ..:: : ... . :. . : * : . . * :.:: .* :. . * . : .. . : : . .. ... . .* *:*: : . :*:**:: .::::* ** .: * . : ...: * *:** :** :* ..**:**:. . :*:** *: ... :.:: . * . . ", "identical_positions": 131, "similar_positions": 239, "identity": "12.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010201-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K7K3-1", "uniprot_id": "A0A0G2K7K3_RAT", "id": "A0A0G2K7K3-1", "name": "", "aln": "MATSPAEPSAGPAAQGEA---AAATEEEEEEARQLLQTLQAAEGEAAAAG-AGEG-AAADS---GSPSGPGSPRETGTEAPTGLRFSPEQVACVCEALLQAGHAGRLSRFLGALPP-AERLRGSDPVLRARALVAFQRGEYAELYQLLESRPFPAAHHAFLQDLYLRARYHEAERARGRALGAVDKYRLRKKFPLPKTIWDGEETVYCFKERSRAALKACYRGNRYPTPDEKRRLATLTGLSLTQVSNWFKNRRQRDRTGTGGGAPCKSESDGNPTTEDESSR-SPEDLERGVASVAAEAPTQSSIFLAGA---TPSATCPASSSILVNGSFLAASSPPAVLLNGSPVIINSLTLGE--------GSSLGPLLLTGGGGTPQPQP--SPQGVSETKTSLVLDPQTGEVR-LDEAQSEAPEAKGVHGTTP----GEEIPGTLPQVVPGPPPASTFPLT------------------------PGAVPSVAAPQVVPLSPSS-------GYPTGLSPTSPLLNLPQVVPTSQVVTLPQAVGPLQLLAAGPGSPVKVAATAGPTN-VHLINSSVGVTALQLPSSATPGNLLLANPVSGSPIVTG---------------------------------------------------VAVQQGR---ILLTATFPTRMLVS------------QVLPPAPSLALPLKQ--------------------------EPAITVPEGALP-------------------------VGPSPTLPEG-------------------------------------HTLGPVSTQPLPPAPAVTS------------ATSLPFSPD-----------SSGLLSSFSAPLPEGLMLSPAAVP--------VWPAGLELSTGVEG-------LGTQATHTVLRLPD-------------PDHQGLLLGATAG-------TEVDEGLEAEAKVLTQLQSVPVEEPLEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70178-1", "uniprot_id": "SIX5_MOUSE", "id": "P70178-1", "name": "Homeobox protein SIX5", "aln": "MATSPAEPSAGPAARGEA---AAATEEQEEEARQLLQTLQAAEGEAAAAG-AGDAAAAADS---GSPSGPGSPRETVTEVPTGLRFSPEQVACVCEALLQAGHAGRLSRFLGALPP-AERLRGSDPVLRARALVAFQRGEYAELYQLLESRPFPAAHHAFLQDLYLRARYHEAERARGRALGAVDKYRLRKKFPLPKTIWDGEETVYCFKERSRAALKACYRGNRYPTPDEKRRLATLTGLSLTQVSNWFKNRRQRDRTGTGGGAPCKSESDGNPTTEDESSR-SPEDLERGVASMAAEAPAQSSIFLAGA---TSPATCPASSSILVNGSFLAASSPPAVLLNGSPVIINSLALGE--------NSSLGPLLLTGG-SAPQPQP--SLQGVSEAKNSLVLDPQTGEVR-LDEAQSEAPETKGVHGTT-----GEEIPGALPQVVPGPPPASTFPLT------------------------PGAVPAVAAPQVVPLSPSS-------GYPTGLSPTSPRLNLPQVVPTSQVVTLPQAVGPLQLLAAGPGSPVKVAAAAGPTN-VHLINSSVGVTALQLPSSTAPGNFLLANPVSGSPIVTG---------------------------------------------------VAVQQGK---IILTATFPTSMLVS------------QVLPPAPSLALPLKQ--------------------------EPAITVPEGALP-------------------------VGPSPTLPEG-------------------------------------HTLGPISTQPLPPASVVTS------------GTSLPFSPD-----------SSGLLSSFSAPLPEGLMLSPAAVP--------VWPAGLELSTGVEG-------LGTQATHTVLRLPD-------------PDPQGLLLGATTG-------TEVDEGLEAEAKVLTQLQSVPVEEPLEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N196-1", "uniprot_id": "SIX5_HUMAN", "id": "Q8N196-1", "name": "Homeobox protein SIX5", "aln": "MATLPAEPSAGPAAGGEAVAAAAATEEEEEEARQLLQTLQAAEGEAAAAAGAGAGAAAAGAEGPGSPGVPGSPPEAASEPPTGLRFSPEQVACVCEALLQAGHAGRLSRFLGALPP-AERLRGSDPVLRARALVAFQRGEYAELYRLLESRPFPAAHHAFLQDLYLRARYHEAERARGRALGAVDKYRLRKKFPLPKTIWDGEETVYCFKERSRAALKACYRGNRYPTPDEKRRLATLTGLSLTQVSNWFKNRRQRDRTGAGGGAPCKSESDGNPTTEDESSR-SPEDLERGAAPVSAEAAAQGSIFLAGT---GPPAPCPASSSILVNGSFLAASGSPAVLLNGGPVIINGLALGE--------ASSLGPLLLTGGGGAPPPQP--SPQGASETKTSLVLDPQTGEVR-LEEAQSEAPETKGAQVAAPGPALGEEVLGPLAQVVPGPPTAATFPLP------------------------PGPVPAVAAPQVVPLSPPP-------GYPTGLSPTSPLLNLPQVVPTSQVVTLPQAVGPLQLLAAGPGSPVKVAAAAGPAN-VHLINSGVGVTALQLPSATAPGNFLLANPVSGSPIVTG---------------------------------------------------VALQQGK---IILTATFPTSMLVS------------QVLPPAPGLALPLKP--------------------------ETAISVPEGGLP-------------------------VAPSPALPEA-------------------------------------HALGTLSAQQPPPAAATTS------------STSLPFSPD-----------SPGLLPNFPAPPPEGLMLSPAAVP--------VWSAGLELSAGTEGLLEAEKGLGTQAPHTVLRLPD-------------PDPEGLLLGATAG-------GEVDEGLEAEAKVLTQLQSVPVEEPLEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N1Z226-1", "uniprot_id": "A0A8N1Z226_DANRE", "id": "A0A8N1Z226-1", "name": "", "aln": "MASLSLES----------------TEQTENGPKESAQNEAKVKEETDPDE--------------------VSEQLLQSFQNSALSFSTDQVACLCEALLQAGNVDRLWRFLATIPPSADLLRGNETLLKAQALVAFHRDEFKELYAILDSHDFHPSNHGFLQDLYLKARYKEAERSRGRSLGAVDKYRLRKKFPLPKTIWDGEETVYCFKEKSRNALKECYKINRYPTPAEKKNLAKVTGLSLTQVSNWFKNRRQRDRTPSG--TNSKSESDGNHSTEDEASKGDLEDITDKPAAQETGSSNASLISVPGAPCGTGQLVLNSPGGFLTSPHPLLLNGSPILSGAGTGVIINGLTLSDGHTVTLSPVTANAPLLLNGAQVISKDERGISDLEAQGSLTTVVLNPQASLTSTIPLSLSEDTKSTSSNVSPLDFISLPEALKNTDNTHPVPANSISLPTISTSVISSTSLSSGILAPNSISASIPGSVSSVISSPVVPLQPTQPPEIVVLGKAEPLSSTCSSFSSPQVLSLPQVVPSIQGVPVSQLMQPPSGTTVSSRPQLVPVSPVNPQLSQVSIPQFPTQTFHMGPRLAQAQPQNGSVTLNTSSALTLPQIADGQVTQVLTPQLGNESTLASLPQIQTSLGTQVIPISSPTQVVPISQTKDSSQMVPLSLPQLMPVSSITGTTGTFSFPQVVPATPSLSIPSHGGAFQILTSGAGTGLSVAQGPIRLSPIGPPQSVPTGTIPGVQLLNSGVIKLPTASPGNILLAGGIGSSPILSVQNGKLILTIPAGIQFASMPVKSVPDNSVSSNSNLDSQISTVHSLENQPAPPLIAQTSNSLQSSPLAFVGSSALYCSPEPGTTANTTPGASPNTPDSSSTPTPTSILQSQQALSPDSMLSLSPICSGVVTGHHLSQPAWSPVPLSSSASLTLFDMRGKGELPEDPALLGLPGGESLLLGTPSPGEDMERDSHLDDDMDGDSKILTQLQSVPVDDDLGL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: . *. **: *: .:: *. .: *: . * : :.* **.:****:********:..** ***.::** *: ***.:.:*:*:*****:*.*: *** :*:*: * .::*.*******:***:****:***:*******************************:** *** **: ****** **:.**.:********************* :* : .******* :****:*: . **: *. : :. . * :.*: :...:*.. * ...* : * ****.*:*.: :: .****.*. . : * .. : .::**:**:. . : : ** .::.. : :. * :. * *. : ::* **.*.:* :. ****.*. * . **.*.. :. ***:. .***. *.* **: . .*:.*. . *.. *: * *.:. : : .: *:* .** :. *.:.* : ::. ::* * ** **:*.:*.*::* : .. :** * :* :..** *. :: .:. * ** . ** .::* **: *.. . .:* * .:: * *:. :*: . . *.:.*. *:: : . *. :.****:.: .:*:.::.::*:*********:: * *", "identical_positions": 268, "similar_positions": 229, "identity": "27.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010202-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P45983-1", "uniprot_id": "MK08_HUMAN", "id": "P45983-1", "name": "Mitogen-activated protein kinase 8", "aln": "MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMG-YKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPT-VRTYVENRPKYAGYSFEKLFPDVLFPADSEHN-KLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEER-------------------TKNGVIRGQPSPLGAAVINGSQHPSSSSSVN-------DVSSMSTDPTLASDTDSSLEAAAGPLGCCR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49185-1", "uniprot_id": "MK08_RAT", "id": "P49185-1", "name": "Mitogen-activated protein kinase 8", "aln": "MSRSKRDNNFYSVEIADSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMG-YKENVDLWSVGCIMGEMVCLKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPT-VRTYVENRPKYAGYSFEKLFPDVLFPADSEHN-KLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEER-------------------TKNGVIRGQPSPLGAAVINGSQHPVSSPSVN-------DMSSMSTDPTLASD------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91Y86-1", "uniprot_id": "MK08_MOUSE", "id": "Q91Y86-1", "name": "Mitogen-activated protein kinase 8", "aln": "MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMG-YKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPT-VRTYVENRPKYAGYSFEKLFPDVLFPADSEHN-KLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEER-------------------TKNGVIRGQPSPLAQVQQ----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9DGD9-1", "uniprot_id": "MK08_DANRE", "id": "Q9DGD9-1", "name": "Mitogen-activated protein kinase 8", "aln": "MNRNKREKEYYSIDVGDSTFTVLKRYQNLRPIGSGAQGIVCSAYDHVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQME-LDHERLSYLLYQMLCGIKHLHAAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAATGLLMTPYVVTRYYRAPEVILGMG-YQANVDVWSIGCIMAEMVRGSVLFPGTDHIDQWNKVIEQLGTPSQEFMMKLNQS-VRTYVENRPRYAGYSFEKLFPDVLFPADSDHN-KLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEVEAPPPAITDKQLDEREHSVEEWKELIYKEVLEWEER-------------------TKNGVIRGQPASLAQVQQ----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P92208-1", "uniprot_id": "JNK_DROME", "id": "P92208-1", "name": "Stress-activated protein kinase JNK", "aln": "--MTTAQHQHYTVEVGDTNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQMD-LDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFMMTPYVVTRYYRAPEVILGMG-YTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPT-VRNYVENRPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDEALKHEYINVWYDAEEVDAPAPEPYDHSVDEREHTVEQWKELIYEEVMDYEAH-------------------NTNNRTR---------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32485-1", "uniprot_id": "HOG1_YEAST", "id": "P32485-1", "name": "Mitogen-activated protein kinase HOG1", "aln": "---MTTNEEFIRTQIFGTVFEITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSP-----LEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDP--QMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENTLKFVTSLPHRDPIPFSERF-------------KTVEPDAVDLLEKMLVFDPKKRITAADALAHPYSAPYHDPTDEPVADAKF-DWHFNDADLPVDTWRVMMYSEILDFHKIGGSDGQIDISATFDDQVAAATAAAAQAQAQAQAQVQLNMAAHSHNGAGTTGNDHSDIAGGNKVSDHVAANDTITDYGNQAIQYANEFQQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.:. :: .: * : .** :*.*:* ** *:**:* * : .: *****: :**.. . ***:***: *:* :.*:*:* * : * . ::*:*:* ** .::* :::* *::: :.*:***:* *:*::*:**:**********::: :* *** ****** . ** ** ********::* * :**:** ***:.**: **** *::.*:. : : **:* ..: : . .:* . *: .*.. * : .:* :**.****:*..:**:. :** * * ::*. : .. . * .:: : .:: *: ::*.*::: . . : ", "identical_positions": 126, "similar_positions": 123, "identity": "27.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010202-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P47811-1", "uniprot_id": "MK14_MOUSE", "id": "P47811-1", "name": "Mitogen-activated protein kinase 14", "aln": "MSQ-ERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTP---ARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADP-YDQSFESRDLLIDEWKSLTYDEVISFVPP-----------------------PLDQEEMES---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16539-1", "uniprot_id": "MK14_HUMAN", "id": "Q16539-1", "name": "Mitogen-activated protein kinase 14", "aln": "MSQ-ERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTP---ARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADP-YDQSFESRDLLIDEWKSLTYDEVISFVPP-----------------------PLDQEEMES---------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70618-1", "uniprot_id": "MK14_RAT", "id": "P70618-1", "name": "Mitogen-activated protein kinase 14", "aln": "MSQ-ERPTFYRQELNKTVWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTP---ARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVAEP-YDQSFESRDFLIDEWKSLTYDEVISFVPP-----------------------PLDQEEMES---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DGE2-1", "uniprot_id": "MK14A_DANRE", "id": "Q9DGE2-1", "name": "Mitogen-activated protein kinase 14A", "aln": "MSQKERPTFYRQEVNKTIWEVPVQYQNLSPVGSGAYGSVCSAFDAKTGFKVAVKKLSRPFQSIIHAKRTYRELRLLKHMRHENVIGLLDVFTP---ATSLKEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNVTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPSSLISRMPSHEARTYISSLPQMPKRNFADVFIGANPQAVDLLEKMLVLDTDKRITAAEALAHPYFAQYHDPDDEPEAEP-FDQSFESRELDIEEWKRQTYEEMISFEPP-----------------------VFDVDEMES---------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O61443-1", "uniprot_id": "MK38B_DROME", "id": "O61443-1", "name": "Mitogen-activated protein kinase p38b", "aln": "MSR-KMAKFYKLDINRTEWEIPETYQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQKLSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPAESEMTGYVATRWYRAPEIMLNWMHYNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTPADEFMSRISSESARNYIRSLPVMPRRNFRDIFRGANPLAIDLLEKMLELDADKRITAEQALAHPYMEKYHDPTDEQTAAL-YDQSFEENELPVEKWREMVFSEVTAFKPT-----------------------AAFAELLPKEQ-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32485-1", "uniprot_id": "HOG1_YEAST", "id": "P32485-1", "name": "Mitogen-activated protein kinase HOG1", "aln": "MTT--NEEFIRTQIFGTVFEITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLS--------PLEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENTLKFVTSLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADALAHPYSAPYHDPTDEPVADAKFDWHFNDADLPVDTWRVMMYSEILDFHKIGGSDGQIDISATFDDQVAAATAAAAQAQAQAQAQVQLNMAAHSHNGAGTTGNDHSDIAGGNKVSDHVAANDTITDYGNQAIQYANEFQQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * : :: * :*:. *::*.*** **:* ** * *. **:**: :**.: : ********:****: ***:* * *:* . ::::*:**.* .:**:.::: : * .:.**:::*********:***.:*********: :**:*:*:* ****** : :*****:**:********.* :*: .****.***:**:: *:.****.**:.*:. * : *:* ..:. : *..: .:: **. * : * .:* *:******* :*..***** :****.* **** ** * :* *:. :: :: *: :.*: * : . ", "identical_positions": 156, "similar_positions": 106, "identity": "35.06%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010202-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70236-1", "uniprot_id": "MP2K6_MOUSE", "id": "P70236-1", "name": "Dual specificity mitogen-activated protein kinase kinase 6", "aln": "--------------------------MSQSKGKKRNP-GLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSADFVDFTSQCLKKNSKERPTYPELMQHPFFTVHESKAADVASFVKLILGD-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M3C5-1", "uniprot_id": "A0ABK0M3C5_RAT", "id": "A0ABK0M3C5-1", "name": "mitogen-activated protein kinase kinase", "aln": "-------------------------MHRDLKGKKRNP-GLKIPREAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSADFVDFTSQCLKKNSKERPTYPELMQHPFFTVHEAKAADVASFVKLILGD-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52564-1", "uniprot_id": "MP2K6_HUMAN", "id": "P52564-1", "name": "Dual specificity mitogen-activated protein kinase kinase 6", "aln": "--------------------------MSQSKGKKRNP-GLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVASFVKLILGD-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DGE0-1", "uniprot_id": "MP2K6_DANRE", "id": "Q9DGE0-1", "name": "Dual specificity mitogen-activated protein kinase kinase 6", "aln": "MEGGSDKESKVFCDSPSPNPKGEMSVPSNVRGKKKLPKELKLPKEVFEKPAPAPTPPRDLDSKAYVTIGEKNFVVKADDLEQIGELGRGAYGVVDKMRHVPSGVIMAVKRIRATVNTQEQKRLLMDLDISMRTVDCFYTVTFYGALFREGDVWICMELMDTSLDKFYKQVHEKGKTIPEDILGKITVSIVKALEHLHSNLSVIHRDVKPSNVLINMQGQVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPETNQKGYNVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADRFSADFVDFTSQCLRKNSTERPTYTELMQHPFFTLHDSKDTDVASFVKTILGD-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O62602-1", "uniprot_id": "O62602_DROME", "id": "O62602-1", "name": "mitogen-activated protein kinase kinase", "aln": "----------------------------MSKRHRLTP--FTIAKE----PEAAIVPPRNLDSRATIQIGDRTFDIDADSLEKICDLGRGAYGIVDKMRHKQTDTVLAVKRIPMTVNIREQHRLVMDLDISMRSSDCPYTVHFYGAMYREGDVWICMEVMSTSLDKFYPKVFLHDLRMEESVLGKIAMSVVSALHYLHAQLKVIHRDVKPSNILINRAGQVKICDFGISGYLVDSIAKTIDAGCKPYMAPERIDPQGNPAQYDIRSDVWSLGIGMIEMATGRYPYDNWRTPFEQLRQVVEDSPPRLPEGTFSPEFEDFIAVCLQKEYMARPNYEQLLKHSFIVEHLQRNTDISEFVARILDLPDAQPAQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: * :.:.:* * .: .***:***:* : **::.* :.**.** * :*******:*:**** :. ::***** *** :**:**:****:***: ** :** ****::**********:*.******* :* :. : *.:****::*:*.**.:**::*.**********:*** ****:************:***:*************:*: * *.::**:***** ***:* *:***.* ***:**:****:..*:** . **.:* ** : **:*: **.* :*::*.*:. * : :*::.** **. ", "identical_positions": 184, "similar_positions": 90, "identity": "50.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010219-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P01275-1", "uniprot_id": "GLUC_HUMAN", "id": "P01275-1", "name": "Pro-glucagon", "aln": "MK-SIYFVAGLFVMLVQGSWQRSLQDTEEKSRSFSASQADPLSDPDQMNEDKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGRGRRDFPEEVAIVEELGRRHADGSFSDEMNTILDNLAARDFINWLIQTKITDRK-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P55095-1", "uniprot_id": "GLUC_MOUSE", "id": "P55095-1", "name": "Pro-glucagon", "aln": "MK-TIYFVAGLLIMLVQGSWQHALQDTEENPRSFPASQTEAHEDPDEMNEDKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGRGRRDFPEEVAIAEELGRRHADGSFSDEMSTILDNLATRDFINWLIQTKITDKK-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IS85-1", "uniprot_id": "A0A0R4IS85_DANRE", "id": "A0A0R4IS85-1", "name": "", "aln": "MKGVQYFASLLLLLFVHKCICVPLQGDSTSTETADSFLARAPG----LTTMKRHSEGTFSNDYSKYLETRRAQDFVQWLMNAKRNGG-------SVKRHAEGTYTSDVSSYLQDQAAQSFVAWLKSGQPKPDVANNKG-ANMAQRRHVDGSFTSDVNKVLDSIAAKEYLQWVMNSKASGTSGKRGGNQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **.: *::::*: . .**. . ...: : : . :. ****:***:.******::************:*** . ..:******:********:.***:.*:*** .*: : *..:: . .: ***.****:.::..:**.:*::::::*::::* :. . ", "identical_positions": 71, "similar_positions": 69, "identity": "37.77%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010226-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LYZ4-1", "uniprot_id": "A0ABK0LYZ4_RAT", "id": "A0ABK0LYZ4-1", "name": "Glial cell line-derived neurotrophic factor", "aln": "MGFGPLGVNVQLGVYGDRIRGAAAGRDSKMKLWDVVAVCLVLLHTASAFP----LPAGKRLL---EAPAED---HSLGHRRVP--FALTSDSNMPEDYPDQFDDVMDFIQATIKRLKRSPDKQAAALPRRERNRQAAAASPENSRGKGR------RG--------QRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCEAAETMYDKILKNLSRSRRLTSDKVGQACCRPVAFDDDLSFLDDSLVYHILRKHSAKRCGCI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48540-1", "uniprot_id": "GDNF_MOUSE", "id": "P48540-1", "name": "Glial cell line-derived neurotrophic factor", "aln": "-----------------------------MKLWDVVAVCLVLLHTASAFP----LPAGKRLL---EAPAED---HSLGHRRVP--FALTSDSNMPEDYPDQFDDVMDFIQATIKRLKRSPDKQAAALPRRERNRQAAAASPENSRGKGR------RG--------QRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCESAETMYDKILKNLSRSRRLTSDKVGQACCRPVAFDDDLSFLDDNLVYHILRKHSAKRCGCI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P39905-1", "uniprot_id": "GDNF_HUMAN", "id": "P39905-1", "name": "Glial cell line-derived neurotrophic factor", "aln": "-----------------------------MKLWDVVAVCLVLLHTASAFP----LPAGKRPP---EAPAED---RSLGRRRAP--FALSSDSNMPEDYPDQFDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENSRGKGR------RG--------QRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q98TU0-1", "uniprot_id": "GDNF_DANRE", "id": "Q98TU0-1", "name": "Glial cell line-derived neurotrophic factor", "aln": "-----------------------------MKLWDILATCLLLLSSVSTRPLFHKLQPSKRAVVRSESPALDPIIDSQPETSNPKQASMEEQYDLTGLYPEQFEDVMDFIEATLGRLRRSSD--VEPQMKRDRVRQKAAANTEKSGGRGRGERKRSRGRARSRDDRVKGQGRGCLLKEIHLNVTDLDLGYRTKEELIFRYCSGPCHDAETNYDKILNNLTHNKKLDKDTPSRTCCRPIAFDDDISFLDDSLEYHTLKKHSAKKCACV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****::*.**:** :.*: * * ..** *:** * * . * :: .: ::. **:**:******:**: **:**.* :*:* ** ***..*:* *:** ** :*:.***:*. ********.***.************.*. *** *****:**::.::* .*. .::****:*****:*****.* ** *:*****:*.*:", "identical_positions": 118, "similar_positions": 57, "identity": "44.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010302-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61572-1", "uniprot_id": "FOXC1_MOUSE", "id": "Q61572-1", "name": "Forkhead box protein C1", "aln": "MQARYSVSSPNSLGVVPYLGGEQSYYRAAAAAAGGGYTAMPAPMSVYSHPAHAEQYPGSMARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDNKQGWQN----SIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAVKDKE---EKGRLHLQEPPPPQAGRQPAPAPPEQAEGSAPGPQPPPVRIQDIKTENGTCPSPPQPLSPAAALGSGSAATVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDAAEPAPPP--QPAPPPHHSQGFSVDNIMTSLRGSPQGSAAELGSGLLASAAASSRAGIAPPLALGAYSPGQSSLYSSPCSQSSSAGSSGGGGGGGGGGGGSSSAAGTGGAATYHCNLQAMSLYAAGERGGHLQGPAGGAGSAAVDDPLPDYSLPPATSSSSSSLSHGGGG------QEASHHPASHQGRLTSWYLNQAGGDLGHLASAAAAAAAAGYPGQQQNFHSVREMFESQRIGLNNSPVNGNSSCQMAFPASQSLYRTSGAFVYDCSKF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LLL4-1", "uniprot_id": "A0ABK0LLL4_RAT", "id": "A0ABK0LLL4-1", "name": "", "aln": "MQARYSVSSPNSLGVVPYLGGEQSYYRAAAAAAGGGYTAMPAPMSVYSHPAHAEQYPGGMARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDNKQGWQN----SIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAVKDKE---EKGRLHLQEPPPPQAGRQPAPAPPEQAEGSAPGPQQPPVRIQDIKTENGTCPSPPQPLSPAAALGSGSAATVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDAAEPAPPP--QPAPPPHHSQGFSVDNIMTSLRGSPQGSAAELGSGLLASAAASSRAGIAPPLALGAYSPGHSSLYSSPCSQSSSAGSSGGGGGGGGGGGGSSSAAGTGGAATYHCNLQAMSLYAAGERGGHLQGPAGGGGSAAVDDPLPDYSLPPATSSSSSSLSHGGGG------QETSHHPASHQGRLTSWYLNQAGGDLGHLASAAAAAAAAGYPGQQQNFHSVREMFESQRIGLNNSPVNGNSSCQMAFPASQSLYRTSGAFVYDCSKF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12948-1", "uniprot_id": "FOXC1_HUMAN", "id": "Q12948-1", "name": "Forkhead box protein C1", "aln": "MQARYSVSSPNSLGVVPYLGGEQSYYRAAAAAAGGGYTAMPAPMSVYSHPAHAEQYPGGMARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDNKQGWQN----SIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAVKDKE---EKDRLHLKEPPPP--GRQPPPAPPEQADGNAPGPQPPPVRIQDIKTENGTCPSPPQPLSPAAALGSGSAAAVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDGADSAPPPPAPSAPPPHHSQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAASSRAGIAPPLALGAYSPGQSSLYSSPCSQTSSAGSSGGGGGGAG------AAGGAGGAGTYHCNLQAMSLYAAGERGGHLQGAPGGAGGSAVDDPLPDYSLPPVTSSSSSSLSHGGGGGGGGGGQEAGHHPAAHQGRLTSWYLNQAGGDLGHLASAAAAAAAAGYPGQQQNFHSVREMFESQRIGLNNSPVNGNSSCQMAFPSSQSLYRTSGAFVYDCSKF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DE25-1", "uniprot_id": "FXC1A_DANRE", "id": "Q9DE25-1", "name": "Forkhead box C1-A", "aln": "MQARYSVSSPNSLGVVPYISSDQSYYR---AAAGGGYTGMPAPMTMYSHAAH-DQYPASMARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNSPDKKVTLNGIYQFIMERFPFYRDNKQGWQN----SIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAMKDKE---DRG---VKEAPSR----QAQPQAREQEQ-SVPGSQ--PVRIQDIKTENGTS-TPPQAVSP-------TLSTVPKIESPDSSSS-MSSGS--PHSIPSTRSLSLDSAGEQHHQ----AP----AQGFSVDNIMTSLRGSPHS-----SGELTPSLVAPSRTGITPTLSLN-YSPNQSSVYSSPCSQNSISTTSN---------------------ATYHCNMQAMSLYAGGDRSGHLG-----TTATTVDETLPDYSITTTTS----SLSHGNLS-----SAQEGHHP--HQGRLASWYLNQAG-DIGHLG--------ATYPAQQQNFHSVREMFESQRIGLNNSPVNGNNSCQMSFPPSQPIYRTSGAFVYDCSKF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32027-1", "uniprot_id": "CROC_DROME", "id": "P32027-1", "name": "Fork head domain-containing protein crocodile", "aln": "---MHTLFSDQNSFTRHYAQTAAGYGSASAVAAASSASAAAAAHYAYDQYSR---YPYSAS-AYGLGAPHQN-KEIVKPPYSYIALIAMAIQNAADKKVTLNGIYQYIMERFPYYRDNKQGWQN----SIRHNLSLNECFVKVARDDKKPGKGSYWTLDPDSYNMFDNGSFLRRRRRFKKKDVMREKEEAIKRQAMMNEKLAEMKPLKLMTNGILEAKHMAAHAAHFKKEPLMDLGCLSGKEVSHAAMLNS----CHDSLAQMNHLAGGGVEHPGFTVDSLMNVYNPRIHHSAYPYHLNEDNLATVASSQMHHVHHAAAAHHAQQLQRHVAHVAHPLTPGGQGAGGQSS--GHSPTTISTPHGPAHGGWYTPETPPSEPVPHNG--------------QQGTPTHPGHNNNNSSSVLNHNGVGNGGGGGGGGGGGSSSVLTSSPTSALG-------------------------FRDMIFEQNQSCQLDTGSPTGSLQSASPPASASVAAASAAAAAAVISSHHHHHHHHAALSGNLGQLGQLSNLSHYRPHVGHYQEYGIKYGV---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40466-1", "uniprot_id": "FKH1_YEAST", "id": "P40466-1", "name": "Fork head protein homolog 1", "aln": "----MSVTSREQKFSGKYSSYTAQDRQGLVNAVTCVLSSSSDPVAVSSDYSN----SLSIAREVNAYA------KIAGCDWTYYVQKLEVTIGRNTDSLNLNAVPGTVVKKNIDIDLGPAKIVSRKHAAIRFNLESGSWELQIFGRNGAKVNFRRIPTGPDSPPTVLQSGCIIDIGGVQMIFILPEQETIISDYCLNHLMPKLLSTYGTNGNNNPLLRNIIEGSTYLREQRLQEEARLQQLDHLHTPLSSSSDVNPIGDPHGDTIMMEEDEEDENYTRGGIRPNTYTSSSNNAVTNGN---------VPHIENPSDLSLD--ENRYIKPPQSYASMITQAILSTPEGSISLADIYKFISDNYAFYR---FSQMAWQNSVR--------------------------------HNLSLNKAFEKVPKRAGQQGKGMNWKISDEVRRDFLN------------------------KWNAGKLSKIRRGASVTRQLQLHMSKFGEIPAPESSSIDPRGIKAQKVKKSLQATSSILGESAPQLQRTQLTGQISTTTSMDVTTNANVNNSSLS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * :. * *. :. . . .. :. . . : . : .:. ::* . . . ..:.**.: ::.: . . :**.**. .. ::: : : . .*** . :.. : .: : ::* . . .. : : . . .. : . . : .. . : . : : . . :. : :: .. * : : . : : . : . : . : .. . . . ", "identical_positions": 15, "similar_positions": 106, "identity": "2.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010302-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61572-1", "uniprot_id": "FOXC1_MOUSE", "id": "Q61572-1", "name": "Forkhead box protein C1", "aln": "MQARYSVSSPNSLGVVPYLGGEQSYYRAAAAAAGGGYTAMPAPMSVYSHPAHAEQYPGSMARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLN-GIYQFIMDRFPFYRDNKQG--WQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAVKDKEEKGRLHLQEPPPPQAGRQPAPAPPEQAEGSAPGPQPPPVRIQDIKTENGTCPSPPQPLSPAAALGSGSAATVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDAAEPAPPP--QPAPPPHHSQGFSVDNIMTSLRGSPQGSAAELGSGLLASAAASSRAGIAPPLALGAYSPGQSSLYSSPCSQSSSAGSSGGGGGGGGGGGGSSSAAGTGGAATYHCNLQAMSLYAAGERGGHLQGPAGGAGSAAVDDPLPDYSLPPATSSSSSSLSHGGGG------QEASHHPASHQGRLTSWYLNQAGGDLGHLASAAAAAAAAGYPGQQQNFHSVREMFESQRIGLNNSPVNGNSSCQMAFPASQSLYRTSGAFVYDCSKF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LLL4-1", "uniprot_id": "A0ABK0LLL4_RAT", "id": "A0ABK0LLL4-1", "name": "", "aln": "MQARYSVSSPNSLGVVPYLGGEQSYYRAAAAAAGGGYTAMPAPMSVYSHPAHAEQYPGGMARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLN-GIYQFIMDRFPFYRDNKQG--WQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAVKDKEEKGRLHLQEPPPPQAGRQPAPAPPEQAEGSAPGPQQPPVRIQDIKTENGTCPSPPQPLSPAAALGSGSAATVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDAAEPAPPP--QPAPPPHHSQGFSVDNIMTSLRGSPQGSAAELGSGLLASAAASSRAGIAPPLALGAYSPGHSSLYSSPCSQSSSAGSSGGGGGGGGGGGGSSSAAGTGGAATYHCNLQAMSLYAAGERGGHLQGPAGGGGSAAVDDPLPDYSLPPATSSSSSSLSHGGGG------QETSHHPASHQGRLTSWYLNQAGGDLGHLASAAAAAAAAGYPGQQQNFHSVREMFESQRIGLNNSPVNGNSSCQMAFPASQSLYRTSGAFVYDCSKF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12948-1", "uniprot_id": "FOXC1_HUMAN", "id": "Q12948-1", "name": "Forkhead box protein C1", "aln": "MQARYSVSSPNSLGVVPYLGGEQSYYRAAAAAAGGGYTAMPAPMSVYSHPAHAEQYPGGMARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLN-GIYQFIMDRFPFYRDNKQG--WQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAVKDKEEKDRLHLKEPPPP--GRQPPPAPPEQADGNAPGPQPPPVRIQDIKTENGTCPSPPQPLSPAAALGSGSAAAVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDGADSAPPPPAPSAPPPHHSQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAASSRAGIAPPLALGAYSPGQSSLYSSPCSQTSSAGSSGGGGGGAG------AAGGAGGAGTYHCNLQAMSLYAAGERGGHLQGAPGGAGGSAVDDPLPDYSLPPVTSSSSSSLSHGGGGGGGGGGQEAGHHPAAHQGRLTSWYLNQAGGDLGHLASAAAAAAAAGYPGQQQNFHSVREMFESQRIGLNNSPVNGNSSCQMAFPSSQSLYRTSGAFVYDCSKF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DE24-1", "uniprot_id": "FXC1B_DANRE", "id": "Q9DE24-1", "name": "Forkhead box C1-B", "aln": "MQARYPVSSQSPLGVVPYIPGDQGFYR---TATGGGYTGMPAPMSMYSHATH-EQYPGGMARAYGPYAPAQQPKDMVKPPYSYIALITMAIQNSSDKKITLN-GIYQFIMERFPFYRDNKQG--WQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVLREKEDRD-------------RQGKDNPGQACEQDAQQP----VKLRDIKTENGACTPPHDSTPP--------LSTVPKTESPDRSGGSACSGSP------------------------QSQTP---QQAFSMDTIMTGLRGSPQ-HAAELP---------ASRAALPGSVSLTYSPTPQPAHYSPPCGQP----------------------------ATYHCNMQATSLYTG-DRG---HG----------DDTLPEYTN--TTNASSISHPHQSSS------QESQHL---QQNRLAPWYLNQSG-ELGHLS--------ASYPGQQQNFHAVREMFETQRIALNSSPVTGSNSCQMAFPSSQPLYRASGAFVYDCSKF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32027-1", "uniprot_id": "CROC_DROME", "id": "P32027-1", "name": "Fork head domain-containing protein crocodile", "aln": "---MHTLFSDQNSFTRHYAQTAAGYGSASAVAAASSASAAAAAHYAYDQYSR---YP-YSASAYGLGAPHQN-KEIVKPPYSYIALIAMAIQNAADKKVTLN-GIYQYIMERFPYYRDNKQG--WQNSIRHNLSLNECFVKVARDDKKPGKGSYWTLDPDSYNMFDNGSFLRRRRRFKKKDVMREK-----------------EEAIKRQAMMNEKLAEMKPLKLMTNGILEAKHMAAHAAHFKKEPLMDLGCLSGKEVSHAAMLNSCHDSLAQMNHLAGGGVEHPGFTVDSLMNVYNPRIHHSAYPYHLNEDNLATVASSQMHHVHHAAAAHHAQQLQR----HVAHVAHPLTPGGQGAGGQSSGHSPTTISTPHGPAHGGWYTPETPPSEPVPHNGQQGTPTHPGHNNNNSSSVLNHNGVGNGGGGGGG---------------GGGGSSSVLTSSPTS------ALGFRDMIFEQNQSCQLDTGSPTGSLQSASPPASASVAAASAAAAAAVISSHHHHHHHHAALSGNLGQLGQLSNLSHYRPHVGHYQEYGIKYGV---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40466-1", "uniprot_id": "FKH1_YEAST", "id": "P40466-1", "name": "Fork head protein homolog 1", "aln": "MSVTSREQKFSGKYSSYTAQDRQGLVNAVTCVLSSSSDPVAVSSDYSNSLSIAREVNAYAKIAGCDWTYYVQKLEVTIGRNTDSLNLNAVPGTVVKKNIDIDLGPAKIVSRKHAAIRFNLESGSWELQIFGRNGAKVNFRRIPTGPDSP------PTVLQSGCIIDIGGVQMIFILPEQETIISDYCLN---------------HLMPKLLSTYGTNGNNNPLLRNIIEGSTYLREQRLQEEARLQQLDHLHTPLSSSSDVNPIGDPHGDTIMMEEDEEDENYTRGGIRPNTYTSSSNNAVTNGNVPHIENPSDLSLDENRYIKPPQSYASMITQAILST----PEGSISLADIYKFISDNYAFYRFSQMAWQN----------------------------SVRHNLSLNKAFEKVPKRAGQQGKG--------------MNWKISDEVRRDFLNKWNAG------KLSKIRRGASVTRQLQLHMSKFG-EIPAPESSSIDPRGIKAQKVKKSLQATSSILGESAPQLQRTQLTGQISTTTSMDVTTNANVNNSSLS------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . ... ... . : * : : ::. : : . . .*:: :: * : : :.. * * :. *: .* . . : * ::. . ..* . :* ::: *.. ::: : : . . . : .: . : .: . : *: . :. . . . : . . . : :* . : .. .: . : *. . : . . .: ", "identical_positions": 14, "similar_positions": 96, "identity": "2.48%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010306-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O94813-1", "uniprot_id": "SLIT2_HUMAN", "id": "O94813-1", "name": "Slit homolog 2 protein", "aln": "---------MRGVGWQMLSLSLGLVLAILNKVAPQA------------------------------------CPAQCSCSGSTVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLRQRPRVGLYTQCMGPSHLRGHNVAEVQKREFVCS----GHQSFMAPSCSVLH-CPAACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPIETSGARCTSPRRLANKRIGQIKSKKFRCSAKEQYFIP-------GTEDYRSKLSGDCFADLACPEKCRCEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLRKKRIVTGNPRCQKPYFLKEIPIQDVAIQDFTCDDGNDDNSCSPLSRCPTECTCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPKE-LSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSDWVKSEYKEPGIARCAGPGEMADKLLLTTPSKKFTC-----------QGPVDVNILAKCNPCLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEEDGFWCICADGFEGENCEVNVDDCE-DNDCENNSTCVDGINNYTCLCPPEYT---------GELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNGYTCICPEGYSGLFCEFS--PPMVLPRTSPCDNFDCQNGAQCIVRIN--EPICQCLPGYQGEKCEKLVSVNFINKESYLQIPSAKVRPQTNITLQIATDEDSGILLYKGDKDHIAVELYRGRVRASYDTGSHPASAIYSVETINDGNFHIVELLALDQSLSLSVDGGNPKIITNLSKQSTLNFDSPLYVGGMPGKSNVASLRQAPGQNGTSFHGCIRNLYINSELQDFQKVPMQTGILPGCEPCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFS---YSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCDREISCRGERIRDYYQKQQGYAACQTTKKVSRLECRGGCAGG-QCCGPLRSKRRKYSFECTDGSSFVDEVEKVVKCGCTRCVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R1B9-1", "uniprot_id": "SLIT2_MOUSE", "id": "Q9R1B9-1", "name": "Slit homolog 2 protein", "aln": "---------MSGIGWQTLSLSLGLVLSILNKVAPQA------------------------------------CPAQCSCSGSTVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKIDFAGLRHLRVLQLMENRISTIERGAFQDLKELERLRLNRNNLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLRQRPRVGLYTQCMGPSHLRGHNVAEVQKREFVCS----GHQSFMAPSCSVLH-CPAACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNSIRVIPPGAFSPYKKLRRLDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTVAKGTFSALRAIQTMHLAQNPFICDCHLKWLADYLHTNPIETSGARCTSPRRLANKRIGQIKSKKFRCS---------------GTEDYRSKLSGDCFADLACPEKCRCEGTTVDCSNQRLNKIPDHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRISCVGNDSFIGLGSVRLLSLYDNQITTVAPGAFDSLHSLSTLNLLANPFNCNCHLAWLGEWLRRKRIVTGNPRCQKPYFLKEIPIQDVAIQDFTCDDGNDDNSCSPLSRCPSECTCLDTVVRCSNKGLKVLPKGIPKDVTELYLDGNQFTLVPKE-LSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSDWVKSEYKEPGIARCAGPGEMADKLLLTTPSKKFTC-----------QGPVDITIQAKCNPCLSNPCKNDGTCNNDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGENAGFWCTCADGFEGENCEVNIDDCE-DNDCENNSTCVDGINNYTCLCPPEYT---------GELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYIGEHCDIDFDDCQDNKCKNGAHCTDAVNGYTCVCPEGYSGLFCEFS--PPMVLPRTSPCDNFDCQNGAQCIIRIN--EPICQCLPGYLGEKCEKLVSVNFVNKESYLQIPSAKVRPQTNITLQIATDEDSGILLYKGDKDHIAVELYRGRVRASYDTGSHPASAIYSVETINDGNFHIVELLTLDSSLSLSVDGGSPKVITNLSKQSTLNFDSPLYVGGMPGKNNVASLRQAPGQNGTSFHGCIRNLYINSELQDFRKMPMQTGILPGCEPCHKKVCAHGMCQPSSQSGFTCECEEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFS---YSCKCLEGHGGVLCDEEEDLFNPCQMIKCKHGKCRLSGVGQPYCECNSGFTGDSCDREISCRGERIRDYYQKQQGYAACQTTKKVSRLECRGGCAGG-QCCGPLRSKRRKYSFECTDGSSFVDEVEKVVKCGCARCAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WVC1-1", "uniprot_id": "SLIT2_RAT", "id": "Q9WVC1-1", "name": "Slit homolog 2 protein", "aln": "---------MSGIGWQTLSLSLALVLSILNKVAPHA------------------------------------CPAQCSCSGSTVDCHGLALRIVPRNIPRNTERLDLNGNNITRITKTDFAGLRHLRILQLMENKISTIERGAFHDLKELERLRLNRNNLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLRQRPRVGLYTQCMGPSHLRGHNVAEVQKREFVCSDEEEGHQSFMAPSCSVLH-CPIACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNSIRVIPPGAFSPYKKLRRLDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTVAKGTFSALRAIQTMHLAQNPFICDCHLKWLADYLHTNPIETSGARCTSPRRLANKRIGQIKSKKFRCS---------------GTEDYRSKLSGDCFADLACPEKCRCEGTTVDCSNQKLNKIPDHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINLSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRISCVGNDSFTGLGSVRLLSLYDNQITTVAPGAFGTLHSLSTLNLLANPFNCNCHLAWLGEWLRRKRIVTGNPRCQKPYFLKEIPIQDVAIQDFTCDDGNDDNSCSPLSRCPSECTCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9QD64-1", "uniprot_id": "A0A8M9QD64_DANRE", "id": "A0A8M9QD64-1", "name": "Slit homolog 1 protein", "aln": "----------------MFVLKSVVLCALLCGAGAQS------------------------------------CPSQCSCSGTAVDCHGQSLRSVPRNIPRNVERLDLNANNLTKITKADFAGLKNLRVLQLMENKISSIERGAFQDLQELERLRLNRNNLQVLPELLFLGTTKLFRLDLSENQIQGIPRKAFRGSTEIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNISRLSVASFNHMPKLRTFRLHSNNLLCDCNVAWLSDWLRQRPRLGLYTQCMAPPSLRGHNIAEVQKKEFMCT----GPQSHSS--CSVLQ-CPELCTCSNNVVDCRGKGLTEIPTNLPETITEIRLEQNSIKIIPAGAFAPYKRLRRIDLSNNQITELASDSFQGLRSLNSLVLYGNKITELPKGLFDGLFSLQLLLLNANKINCLRVDSFQDLQNLNLLSLYDNKLQTIAKGTFSSLRAIQTLHLAQNPFMCDCHLKWLADYLQDNPIETSGARCTSPRRLANKRIGQIKSKKFRCSAKEQYFIPGIHHINKCVEDYRSKLGGDCFADLACPEKCRCEGTTVDCSGQKLTKIPDHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINLSNNKITDIEEGTFEGASGVNELILTSNRLEGVHYSMLKGLGGLRTLMLRSNRISCVNNGSFTGLSSVRLLSLYDNLITSMSPGAFDTLHSLSTLNLLANPFNCNCHLAWLGEWLRKKRIVTGNPRCQSPYFLKEIPIQDVAVQDFACEEGNDENSCSPLARCPAECSCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNEFTQVPLE-LSNYKHLTLIDLSNNQISTLSNHSFSNMSELLTLILSYNRLRCIPAKAFDGLKSLRLLSLHGNDIAVIPDGAFKDLSSLSHLALGANPLYCDCHMQWLSDWVKSGYKEPGIARCTGPGDMTDKLLLTTPSKKFTCTEVPGTCGFPVPGPVDVSILAKCNPCLSNPCKNDGTCSNHPVDFYRCTCPYGFKGQDCEEPIHACISNPCQNGGTCHLKDGEENTHWCVCPEGFEGDECEINIDDCE-DNDCENNSTCVDGINNYTCLCSPEYTAANNNEVEKGELCEDKLDFCASELNLCQHDSKCILTAKGFMCECTPGYTGEHCEVDFDDCEDNKCKNGAQCIDAVNGYTCVCPEGYSGLFCEFS--PPMVLPRTSPCDHYDCANGAQCVVKDT--DPVCQCLPGYEGVHCERLVSVNFINRESFLQIPSNLITEQANISLQIATDEDNGVLLYKGDNEHIAVELYRGRLRVSYDSGSYPPSAIYSVETINDGSFHVVELVAKDQSLSLSIDGGSPKSINTANSPSPVPSPAPLYLGGLPQQSGLASLRQGSGRNGSSFHGCIRNLYINDQLQDLTQFLLQEGVVPGCQPCQRSMCAHGQCHATGQSSFSCECEAGWTGPLCDQQVNNPCDGNKCIHGSCMAINSYS---YSCRCLPGFAGVLCDEEEQLS-PCQYIACKYGRCRVSGLGKAYCECNSGYTGQSCDREMACRGERVRDHYQTQQGYAACQSTEKVSRLECRGSCGDGTSCCAPLRSKRRKYTFQCTDGSSFVQEVEKVVKCGCTKCPS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P24014-1", "uniprot_id": "SLIT_DROME", "id": "P24014-1", "name": "Protein slit", "aln": "MAAPSRTTLMPPPFRLQLRLLILPILLLLRHDAVHAEPYSGGFGSSAVSSGGLGSVGIHIPGGGVGVITEARCPRVCSCTGLNVDCSHRGLTSVPRKISADVERLELQGNNLTVIYETDFQRLTKLRMLQLTDNQIHTIERNSFQDLVSLERLRLNNNRLKAIPENFVTSSASLLRLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFACDCHLSWLSRFLRSATRLAPYTRCQSPSQLKGQNVADLHDQEFKCS----GLTEHAPMECGAENSCPHPCRCADGIVDCREKSLTSVPVTLPDDTTELRLEQNFITELPPKSFSSFRRLRRIDLSNNNISRIAHDALSGLKQLTTLVLYGNKIKDLPSGVFKGLGSLQLLLLNANEISCIRKDAFRDLHSLSLLSLYDNNIQSLANGTFDAMKSIKTVHLAKNPFICDCNLRWLADYLHKNPIETSGARCESPKRMHRRRIESLREEKFKCS----------------WDELRMKLSGECRMDSDCPAMCHCEGTTVDCTGRGLKEIPRDIPLHTTELLLNDNELGRISSDGLFGRLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKIKEISNKMFLGLHQLKT------------------------LNLYDNQISCVMPGSFEHLNSLTSLNLASNPFNCNCHLAWFAEWLRKKSLNGGAARCGAPSKVRDVQIKDLPHSEFKCSSENSE-GCLGDGYCPPSCTCTGTVVRCSRNQLKEIPRGIPAETSELYLESNEIEQIHYERIRHLRSLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKLQCLQRHALSGLNNLRVLSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDWIKLDYVEPGIARCAEPEQMKDKLILSTPSSSFVCR-----------GRVRNDILAKCNACFEQPCQNQAQCVALPQREYQCLCQPGYHGKHCEFMIDACYGNPCRNNATCTVLE--EGRFSCQCAPGYTGARCETNIDDCLGEIKCQNNATCIDGVESYKCECQPGFS---------GEFCDTKIQFCSPEFNPCANGAKCMDHFTHYSCDCQAGFHGTNCTDNIDDCQNHMCQNGGTCVDGINDYQCRCPDDYTGKYCEGHNMISMMYPQTSPCQNHECKHGVCFQPNAQGSDYLCRCHPGYTGKWCEYLTSISFVHNNSFVELEPLRTRPEANVTIVFSSAEQNGILMYDGQDAHLAVELFNGRIRVSYDVGNHPVSTMYSFEMVADGKYHAVELLAIKKNFTLRVDRGLARSIINEGSNDYLKLTTPMFLGGLPVDPAQQAYKNWQIRNLTSFKGCMKEVWINHKLVDFGNAQRQQKITPGCALLE----GEQQEEEDDEQDFMDET------PHIKEEPVDPCLENKCRRGSRCVPNSNARDGYQCKCKHGQRGRYCDQGEGSTEPPTVTAAS-----------------------------TCRKEQVREYYTEN----DCRSRQPLKYAKCVGGCGN--QCCAAKIVRRRKVRMVCSNNRKYIKNLDIVRKCGCTKKCY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : :* . :: ** ***:* *** .* ***:*. :.***:*:.**:* * : ** * :**:*** :*:* :***.:*:** .*******.*.*: :** :. .::.* ***:*:* * : *:.*:*: .::.**** ***:*::: **:.* :**:*******:: *. *. : :**::** .* : ***:::*** :**. .*:. **:* .*. *:*:*:*:::.:** *: * .. . *.. : ** * *::.:**** *.**.:*..**: **:***** * :*. :*:.:::***:*****:*:.:* *::.**:.*.:********.:**..:*.** **********:*.*:* *:*:**:.*.*******::*::*:***..:::*:*:***:***:***:*:******: ********** **:*: .:** .::.:**:** :: * **.*:* * ** *:********:.: *.:** .** :*:** **:**: :.: *:* :**:* *:::..*::*.** .:***** ::*: * .*::: : .*: ** *:* *.**** *: : **:* *:**::*** :*******:***:.****:* : * .** * :::: *:*:. .:* *.. *.: .* . **..*:* .******.: ** :*:*** :.:****:.*:: : ", "identical_positions": 341, "similar_positions": 250, "identity": "21.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010306-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O75094-1", "uniprot_id": "SLIT3_HUMAN", "id": "O75094-1", "name": "Slit homolog 3 protein", "aln": "MAPGWAGVGAAVRARLALALALASVLSGPPAVACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAP-HSEPPSCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIVKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEESSCQLS-PRCPEQCTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCK----------GPVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQ-TSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLITVNFVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQFHSVELVTLNQTLNLVVDKGTPKSLGKLQKQPAVGINSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEAR-DPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQENPCLGQVVREVIRRQKGYASCATASKVPIMECRGGCGP-QCCQPTRSKRRKYVFQCTDGSSFVEEVERHLECGCLACS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WVB4-1", "uniprot_id": "SLIT3_MOUSE", "id": "Q9WVB4-1", "name": "Slit homolog 3 protein", "aln": "MALGRTGAGAAVRARLALGLALASILSGPPAAACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSIIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGVTGVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTIGQFTLCMAPVHLRGFSVADVQKKEYVCPGP-HSEAPACNANSLSCPSACSCSNNIVDCRGKGLTEIPANLPEGIVEIRLEQNSIKSIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIPKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFVPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRNRFSSECFMDLVCPEKCRCEGTIVDCSNQKLARIPSHLPEYTTDLRLNDNDISVLEATGIFKKLPNLRKINLSNNRIKEVREGAFDGAAGVQELMLTGNQLETMHGRMFRGLSSLKTLMLRSNLISCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHMAWLGRWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEESSCQLS-PRCPEQCTCVETVVRCSNRGLHALPKGMPKDVTELYLEGNHLTAVPKELSAFRQLTLIDLSNNSISMLTNHTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPESMADRLLLTTPTHRFQCK----------GPVDINIVAKCNACLSSPCKNNGTCSQDPVEQYRCTCPYSYKGKDCTVPINTCVQNPCEHGGTCHLSENLRDGFSCSCPLGFEGQRCEINPDDCEDNDCENSATCVDGINNYACLCPPNYTGELCDEVIDYCVPEMNLCQHEAKCISLDKGFRCECVPGYSGKLCETNNDDCVAHKCRHGAQCVDEVNGYTCICPQGFSGLFCEHPPPMVLLQ-TSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLITVNFVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQFHSVELVMLNQTLNLVVDKGAPKSLGKLQKQPAVGSNSPLYLGGIPTSTGLSALRQGADRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSCTVCRHGLCRSVEKDSVVCECHPGWTGPLCDQEAR-DPCLGHSCRHGTCMATGDSYVCKCAEGYGGALCDQKNDSASACSAFKCHHGQCHISDRGEPYCLCQPGFSGHHCEQENPCMGEIVREAIRRQKDYASCATASKVPIMECRGGCGS-QCCQPIRSKRRKYVFQCTDGSSFVEEVERHLECGCRACS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58H752-1", "uniprot_id": "A0AC58H752_DANRE", "id": "A0AC58H752-1", "name": "", "aln": "-MMRWVKYWGTVAVLCGL---LSCAVNG-----CPHKCSCSGSHVDCQGQAFKTVPRGIPRNAERLDLDRNNITRITKVDFSGLKNLRVLHLENNQISVIERGAFEGLKQLERIRLNRNRLQVLPELLFQSTTKLSRLDLSENQIQAVPRKAFRGITTVKNLQLDSNHISCIEDGAFRALRDLEILTLNNNNITLIPLSSFNHMPKLRTLRLHSNNLHCDCHLSWLSDWLRQRRGLAPFTQCMAPAHMRGLNVPDVQKREFVCTGPVETEPRSCAPQVTICPAACTCNNNIVDCRRKGLTEIPANLPEGIVEIRLEQNMIKNIPAGAFSTYKKLKRIDLSKNQISEIAEDAFSGLRSLTSLVLYGNKIAEIPKGLFDGLVSLQLLLLNANKINCLRVNTFKDLQNLNLLSLYDNKLQTISKGLFAPLRAIKTLHLAQNPFMCDCHLKWLADYLFDNPIETSGARCSHPRRLANKRISQVKGKKFRCTGAEDYRSRLSGECFQDLVCPERCRCEGTVVDCSNLKLTKIPPHLPEHTTDLRLNDNEISILEATGAFKKLPNLRKINLSNNKLRDIREGAFDGAGGVLELLLTGNKLQSVSGRMFKGLIGLKTLMLRSNQISCVDNATFTGLSSVRLLSLYDNRISTIAPGAFNTLHSLSTINLLSNPYVCDCHLAWLGLWLKKTRVVSGNPRCQKPAFLKEIPIQDVAMPDFSCDGAEENVCLPSAPRCPESCTCSETVVRCSNRGLRSLPKTIPKDTTELYLEGNLLTSVPKELPNLKQLTLLDLSNNSISHLAPLTFSNMTQLATLILSYNQIRCVPVHAFDGLRSLRLLTLHGNDLSTVPEGAFNHLTSLSHLALGANPLYCDCELRWLSQWVKAGFKEPGIARCTGPPDMADRLLLTTPLNRFQCKDAALEMPHTSGPADLNLMSKCAPCLATPCQNNGTCVSDVTGSYHCTCPFGYKGRNCEIPINACISLPCTNGGTCHLTPGLDGQYSCVCPPGYEGQQCELNPDDCEDNDCENNSTCVDGINNYTCVCPPNYKGDLCEEVVDPCLPGFDLCQHDSKCVPLSKGYRCECLPGYVGQQCEQDYNDCLENKCQHGAECVDAINGYTCVCKEGFSGLFCENHPPMVLLQNTSPCDQSDCQNGSECLVMEGEPVCRCLPGYFGTKCQKMVTLHFLGKEAYVELSGTRIRPPMHISFQVATDKDNGILLYKEDHDPLALELYQGHIRLIYDISKYPPTTVYSVESVNDGLFHTVEVLIQNQTLSLVVDKGTPKSLGKLPRPPAVDHNTQLYIGGVPSLIGTSGLRPG---PFQSFNGCLHDVRLNGELQDLGAGLAGIEGVLFGCHSCSVCDQGACRQRGDEGVTCDCPTGHSGPLCEQMSSQDPCESSRCVHGECVAKGSSYSCLCVDGYSGQFCD-RQDESSACKGLHCVYGECRLTESGEPACHCQPGYSGPTCETELTCEGEAVRDYLYRQMAHKICTSTSRVQRLECRHSCSSGLCCAPTKSRRRKLSFKCPDGSSFSEEMEITVECGCTKCSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:* . .* *:. :.* ** **:**.: ***:* .:::************************:**:***********:**:*:******:.******:***:*:************.**:**********.:*******:* *******.***************************: * ::*******:********:*:*****:********** :. ** ****.*:**:.*.****:*:**..* .:*. :* .: **:.*:*.******* *** ****************** ** ******: ********:******:** ***.**:************:** ****************************:***********************.**::*:*********:************ ************ ***********:*.*****:*:****.*:*.*** ******:******:***** **.:**.****:.********::*:***** ***************:::::********..* **:****:*::: **:*:** .********* *.**.* **:***************:**:****.** ***********: *:**:**** **:* *:********** ***********: **:*** **. * * *****.*** ********:**::**: :***.******** **:**:**. :::***:******** *: *****::*:*******::**:*****:******:*******:*:****:**.**********:***:***.*****:*****:********:.* ********** :***** **.*:*:::** .**::**:***** .* . *:*:**:.***::* :***:*:. ** :******: . . :** ** *:***:**:************.:*********.*:*****.*:**:**:* *:* ::****::**:.*.**: ***:*** *: ** : :**: :**:***:*** :***** * :**** ***: ******* ****** :****::*:*:: **.*** **: *.:*:*::*::*:**::****:.:::** :**:************** *:***********:**:** . *********:**** **:**:: ****.******:******* : ***. *: **:**:*: * *.** * *: .*:**:*:**:*.****: * . ** **:**:** :* **. .:.*.*:* .* :****:* : *** . * ** *:*.* ** * *.:**.* :** ::*.:.**..::* :*:*:::: *** * ****:** *: * .* *: **: : ** : *:::*:* :*** .*.. ** * :*:*** *:*.***** **:* :**** ** ", "identical_positions": 1027, "similar_positions": 318, "identity": "66.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010308-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R7Y1-1", "uniprot_id": "M0R7Y1_RAT", "id": "M0R7Y1-1", "name": "Olfactory receptor", "aln": "-------------------------------------------------------MQLLNQTEVTLASFFLTGTPDLEDMHIW-ISIPFCSMYAIAVVGNCGLLYLIFFEDT-LHRSMYYFLAMLSLTDLVMCSASIPKTLCIFWFHLKEISFIDCLVQMFFIHTFTAMESGVLMLMALDRYVAICYPLHYSTILTNPIIVKAGLATFLRAVVLIIPLIFITKQLPFCRSSILIHHTYCDQLSVAKVSCGNIKVNIVYGLMIALFIGGFDILCITVSYTMILRAVVSLSSADARQKAFSTCTAHICAIIFSYSPAFFCFFSHRFGGHTIPPSCLIIVANLYLLLPPTMNPVVYG------------------VKTKQIR-----------DCVIRILS--------GSKDSKAPSI----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZF02-1", "uniprot_id": "D3ZF02_RAT", "id": "D3ZF02-1", "name": "Olfactory receptor", "aln": "-----------------------------------------------------MVMSVQNNTDLTPASFVLNGIPGLEDIHIW-ISFPFCSMYAVAMMGNCGLLYLIVFEDS-LHRPMYYFLAMLSLTDLVICSSIIPKALCIFWFHQKEIGFDDCLVQMFFTHTFTGVESGVLMLMALDRYIAICYPLCYSTILTNAIIAKIGIATFLRGALLIIPIIFVIKYLPYCRG-NIINHTYCDHMSVAKLSCGNVKVNAIYGLMVALLIGGFDILCITVSYTM--RAVVSLSSADARQKAFSTCTAHICAIVFSYSPALFSLFSHWFGGHTFPPSCHIIVANIYLLLPPTMNPIVYG------------------VKMKQIR-----------DCVIRILS--------GSKDFKAHSI----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0R9M1-1", "uniprot_id": "M0R9M1_RAT", "id": "M0R9M1-1", "name": "", "aln": "-------------------------------------------------------MSLLNVSSLTPASLILNGIPGLEEVNLC-IFFPLFTMYSIALTGNFGLIYLIYSEEV-LHRPMYIFLALLSFTDVLMCTSTIPNTLFISWFNFKKIDFKACLAQMFFVHTFTGMESGVLVLMVLDLYIAMCYPLRYATILTNVVIAKAGMLTFLRGVALVIPFIFLTKRFPYCKG-NVIPHTYCDHISVAKISCGNVQINAIYGLMVVLLIGDFDIPCITVSYTMILWAAVSLSSADARQKAFSTCTAHICAIVITYVPAFFTFFTHRFGWHTIPSHIHIIMANLYLLMPPTMNPIVYG------------------VKTKQIQ-----------KRVIRFFF--------KGRENSSHKF----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A8A3-1", "uniprot_id": "D4A8A3_RAT", "id": "D4A8A3-1", "name": "Olfactory receptor", "aln": "-------------------------------------------------------MPVIWLNTSS-CPFLLTGFPSLEKAHHL-ISLPLLMAYISILLGNGTLLFLIKDDHN-LHEPMYYFLGMLAATDLGVTLTTMPTVLGVLWLNHREIGHGACFSQAYFIHTLSIVESGVLLAMAYDRFVAIRNPLRYTTILTDTRVIKIGIGVVMRAGLSIMPIIIRLHWFPYCQS-HVLSHAFCLHQDVIKLACADITFNRLYPVVVVFCMGLLDFLVICFSYFLILKTVMSIASTDERTKALNTCVSHICCILVFYGTEVGLTFIHRFG-KNIPHIVHITVSYICFLFPPFMNPVIFS------------------IKTKQIQ-----------ISLLRLFS--------PPYSRTQP------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGB8-1", "uniprot_id": "O4F15_HUMAN", "id": "Q8NGB8-1", "name": "Olfactory receptor 4F15", "aln": "------------------------------------------------------MNG---MNHSVVSEFVFMGLTNSREIQLL-LFVFSLLFYFASMMGNLVIVFTVTMDAH-LHSPMYFLLANLSIIDMAFCSITAPKMICDIFKKHKAISFRGCITQIFFSHALGGTEMVLLIAMAFDRYMAICKPLHYLTIMSPRMCLYFLATSSIIGLIHSLVQLVFVVDLPFCGPN-IFDSFYCDLPRLLRLACTNTQELEFMVTVNSGLISVGSFVLLVISYI-FILFTVWKHSSGGLAKALSTLSAHVTVVILFFGPLMFFYTWPSPT---SHL--DKYLAIFDAFITPFLNPVIYT------------------FRNKDMK-----------VAMRRLCS--------RLAHFTKIL-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGB9-1", "uniprot_id": "OR4F6_HUMAN", "id": "Q8NGB9-1", "name": "Olfactory receptor 4F6", "aln": "------------------------------------------------------MDE---ANHSVVSEFVFLGLSDSRKIQLL-LFLFFSVFYVSSLMGNLLIVLTVTSDPR-LQSPMYFLLANLSIINLVFCSSTAPKMIYDLFRKHKTISFGGCVVQIFFIHAVGGTEMVLLIAMAFDRYVAICKPLHYLTIMNPQRCILFLVISWIIGIIHSVIQLAFVVDLLFCGPN-ELDSFFCDLPRFIKLACIETYTLGFMVTANSGFISLASFLILIISYI-FILVTVQKKSSGGIFKAFSMLSAHVIVVVLVFGPLIFFYIFPFPT---SHL--DKFLAIFDAVITPVLNPVIYT------------------FRNKEMM-----------VAMRRRCS--------QFVNYSKIF-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH21-1", "uniprot_id": "OR4F5_HUMAN", "id": "Q8NH21-1", "name": "Olfactory receptor 4F5", "aln": "----------------------------------------------------------------MVTEFIFLGLSDSQELQTF-LFMLFFVFYGGIVFGNLLIVITVVSDSH-LHSPMYFLLANLSLIDLSLSSVTAPKMITDFFSQRKVISFKGCLVQIFLLHFFGGSEMVILIAMGFDRYIAICKPLHYTTIMCGNACVGIMAVTWGIGFLHSVSQLAFAVHLLFCGPN-EVDSFYCDLPRVIKLACTDTYRLDIMVIANSGVLTVCSFVLLIISYT-IILMTIQHRPLDKSSKALSTLTAHITVVLLFFGPCVFIYAWPFPI---KSL--DKFLAVFYSVITPLLNPIIYT------------------LRNKDMK-----------TAIRQLRK--------WDAHSSVKF-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGD3-1", "uniprot_id": "OR4K5_HUMAN", "id": "Q8NGD3-1", "name": "Olfactory receptor 4K5", "aln": "------------------------------------------------------MDK---SNSSVVSEFVLLGLCSSQKLQLF-YFCFFSVLYTVIVLGNLLIILTVTSDTS-LHSPMYFLLGNLSFVDICQASFATPKMIADFLSAHETISFSGCIAQIFFIHLFTGGEMVLLVSMAYDRYVAICKPLYYVVIMSRRTCTVLVMISWAVSLVHTLSQLSFTVNLPFCGPN-VVDSFFCDLPRVTKLACLDSYIIEILIVVNSGILSLSTFSLLVSSYI-IILVTVWLKSSAAMAKAFSTLASHIAVVILFFGPCIFIYVWPFTI---SPL--DKFLAIFYTVFTPVLNPIIYT------------------LRNRDMK-----------AAVRKIVN--------HYLRPRRISEMSLVVRTSFH------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGC6-1", "uniprot_id": "OR4KH_HUMAN", "id": "Q8NGC6-1", "name": "Olfactory receptor 4K17", "aln": "------------------------------------------------------MKL---LNQSQVSEFILLGLTSSQDVEFL-LFALFSVIYVVTVLGNLLIIVTVFNTPN-LNTPMYFLLGNLSFVDMTLASFATPKVILNLLKKQKVISFAGCFTQIFLLHLLGGVEMVLLVSMAFDRYVAICKPLHYMTIMNKKVCVLLVVTSWLLGLLHSGFQIPFAVNLPFCGPN-VVDSIFCDLPLVTKLACIDIYFVQVVIVANSGIISLSCFIILLISYS-LILITIKNHSPTGQSKARSTLTAHITVVILFFGPCIFIYIWPFGN---HSV--DKFLAVFYTIITPILNPIIYT------------------LRNKEMK-----------ISMKKLWR--------AFVNSREDT-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH42-1", "uniprot_id": "OR4KD_HUMAN", "id": "Q8NH42-1", "name": "Olfactory receptor 4K13", "aln": "------------------------------------------------------MER---ANHSVVSEFILLGLSKSQNLQIL-FFLGFSVVFVGIVLGNLLILVTVTFDSL-LHTPMYFLLSNLSCIDMILASFATPKMIVDFLRERKTISWWGCYSQMFFMHLLGGSEMMLLVAMAIDRYVAICKPLHYMTIMSPRVLTGLLLSSYAVGFVHSSSQMAFMLTLPFCGPN-VIDSFFCDLPLVIKLACKDTYILQLLVIADSGLLSLVCFLLLLVSYG-VIIFSVRYRAASRSSKAFSTLSAHITVVTLFFAPCVFIYVWPFSR---YSV--DKILSVFYTIFTPLLNPIIYT------------------LRNQEVK-----------AAIKKRLC--------I-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH43-1", "uniprot_id": "OR4L1_HUMAN", "id": "Q8NH43-1", "name": "Olfactory receptor 4L1", "aln": "------------------------------------------------------MDL---KNGSLVTEFILLGFFGRWELQIF-FFVTFSLIYGATVMGNILIMVTVTCRST-LHSPLYFLLGNLSFLDMCLSTATTPKMIIDLLTDHKTISVWGCVTQMFFMHFFGGAEMTLLIIMAFDRYVAICKPLHYRTIMSHKLLKGFAILSWIIGFLHSISQIVLTMNLPFCGHN-VINNIFCDLPLVIKLACIETYTLELFVIADSGLLSFTCFILLLVSYI-VILVSVPKKSSHGLSKALSTLSAHIIVVTLFFGPCIFIYVWPFSS---LAS--NKTLAVFYTVITPLLNPSIYT------------------LRNKKMQ-----------EAIRKLRF--------QYVSSAQNF-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGD2-1", "uniprot_id": "OR4K2_HUMAN", "id": "Q8NGD2-1", "name": "Olfactory receptor 4K2", "aln": "------------------------------------------------------MDV---GNKSTMSEFVLLGLSNSWELQMF-FFMVFSLLYVATMVGNSLIVITVIVDPH-LHSPMYFLLTNLSIIDMSLASFATPKMITDYLTGHKTISFDGCLTQIFFLHLFTGTEIILLMAMSFDRYIAICKPLHYASVISPQVCVALVVASWIMGVMHSMSQVIFALTLPFCGPY-EVDSFFCDLPVVFQLACVDTYVLGLFMISTSGIIALSCFIVLFNSYV-IVLVTVKHHSSRGSSKALSTCTAHFIVVFLFFGPCIFIYMWPLSS---FLT--DKILSVFYTIFTPTLNPIIYT------------------LRNQEVK-----------IAMRKLKN--------RFLNFNKAMPS---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VG74-1", "uniprot_id": "Q8VG74_MOUSE", "id": "Q8VG74-1", "name": "Olfactory receptor", "aln": "--------------------------------------------------------M---ENYTRVKELIFLGLTQSQEVSMV-LFLFLLLVYVTTLLGNLLIMVTVTCESR-LHTPMYFLLRNLSVADICFSSITAPKVLVDLLSDRKTISFNGCLTQMFFFHLIGGVDVFSLSVMALDRYVAISKPLHYVTIMSRGRCIGLIVASWVGGFAHSIVQISLLLTLPFCGPN-VLDTFYCDVPQVIKLACTDIFVLELLMISNNGLVATLWFVLLVVSYT-VILMMLRSHSGEGRKKAISTCTSHITVVTLHFVPCIYVYARPFTA---LPT--DKAISVTFTVISPLLNPLIYT------------------LRNQEMK-----------SAMRRLRK--------RLEPFDREEQ----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGJ1-1", "uniprot_id": "OR4D6_HUMAN", "id": "Q8NGJ1-1", "name": "Olfactory receptor 4D6", "aln": "------------------------------------------------------MDQ---INHTNVKEFFFLELTRSRELEFF-LFVVFFAVYVATVLGNALIVVTITCESR-LHTPMYFLLRNKSVLDIVFSSITVPKFLVDLLSDRKTISYNDCMAQIFFFHFAGGADIFFLSVMAYDRYLAIAKPLHYVTMMRKEVWVALVVASWVSGGLHSIIQVILMLPFPFCGPN-TLDAFYCYVLQVVKLACTDTFALELFMISNNGLVTLLWFLLLLGSYT-VILVMLRSHSGEGRNKALSTCTSHMLVVTLHFVPCVYIYCRPFMT---LPM--DTTISINNTVITPMLNPIIYS------------------LRNQEMK-----------SAMQRLQR--------RLGPSESRKWG---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q15615-1", "uniprot_id": "OR4D1_HUMAN", "id": "Q15615-1", "name": "Olfactory receptor 4D1", "aln": "------------------------------------------------------MEP---QNTTQVSMFVLLGFSQTQELQKF-LFLLFLLVYVTTIVGNLLIMVTVTFDCR-LHTPMYFLLRNLALIDLCYSTVTSPKMLVDFLHETKTISYQGCMAQIFFFHLLGGGTVFFLSVMAYDRYIAISQPLRYVTIMNTQLCVGLVVAAWVGGFVHSIVQLALILPLPFCGPN-ILDNFYCDVPQVLRLACTDTSLLEFLMISNSGLLVIIWFLLLLISYT-VILVMLRSHSGKARRKAASTCTTHIIVVSMIFIPCIYIYTWPFTP---FLM--DKAVSISYTVMTPMLNPMIYT------------------LRNQDMK-----------AAMRRLGK--------CLVICRE-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH83-1", "uniprot_id": "OR4A5_HUMAN", "id": "Q8NH83-1", "name": "Olfactory receptor 4A5", "aln": "------------------------------------------------------MR-----QNNNITEFVLLGFSQDPGVQKA-LFVMFLLTYLVTVVGNLLIVVDIIASPS-LGSPMYFFLACLSFIDAAYSTTISPKLIVGLFCDKKTISFQGCMGQLFIDHFFGGAEVFLLVVMACDRYVAICKPLHYLTIMNRQVCFLLLVVAMIGGFVHSAFQIV-VYSLPFCGPN-VIVHFSCDMHPLLELACTDTYFIGLTVVVNSGAICMVIFNLLLISYG-VILSSLKTYSQEKRGKALSTCSSGSTVVVLFFVPCIFIYVRPVSN---FPT--DKFMTVFYTIITHMLSPLIYT------------------LRNSEMR-----------NAIEKLLG--------KKLTIF---IIGGVSVLM--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH70-1", "uniprot_id": "O4A16_HUMAN", "id": "Q8NH70-1", "name": "Olfactory receptor 4A16", "aln": "------------------------------------------------------MR-----PSSNVTEFVLLGLTQDPDVKKT-LFVMFLLIYIVTMVGNLLIWVTTIGSPS-LGSLMYFFLAYLSLMDAIYSTAMSPKLMIDLLCDKIAISLSACMGQLFIEHLLGGAEVFLLVVMAYDRYVAISKPLHYLNIMNRLVCILLLVVAMIGGFVHSVVQIVFLYSLPICGPN-VIDHSVCDMYPLLELLCLDTYFIGLTVVANGGIICMVIFTFLLISCG-VILNFLKTYSQEERHKALPTCISHIIVVALVFVPCIFMYVRPVSN---FPF--DKLMTVFYSIITLMLNPLIYS------------------LRQSEMK-----------NAMKNLWC--------EKLSIVRKRVSPTLNIFIPSSKATNRR-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IF82-1", "uniprot_id": "O4A47_HUMAN", "id": "Q6IF82-1", "name": "Olfactory receptor 4A47", "aln": "------------------------------------------------------ME-----PRKNVTDFVLLGFTQNPKEQKV-LFVMFLLFYILTMVGNLLIVVTVTVSET-LGSPMYFFLAGLSFIDIIYSSSISPRLISGLFFGNNSISFQSCMAQLFIEHIFGGSEVFLLLVMAYDCYVAICKPLHYLVIMRQWVCVVLLVVSWVGGFLHSVFQLSIIYGLPFCGPN-VIDHFFCDMYPLLKLVCTDTHAIGLLVVANGGLACTIVFLLLLISYG-VILHSLKNLSQKGRQKALSTCSSHMTVVVFFFVPCIFMYARPART---FPI--DKSVSVFYTVITPMLNPLIYT------------------LRNSEMT-----------SAMKKLWR--------RDLISSST------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGN8-1", "uniprot_id": "OR4A4_HUMAN", "id": "Q8NGN8-1", "name": "Putative olfactory receptor 4A4", "aln": "------------------------------------------------------ME-----PRKNVTDFVLLGFTQNPKEQKV-LFVMFLLFYILTMVGNLLIVVTVTVSET-LGSPMSFFLAGLTFIDIIYSSSISPRLISDLFFGNNSISFQSFMAQLFIEHLFGGSEVFLLLVMAYDRYVAICKPLHYLVIMRQWVCVLLLVVSWVGGFLQSVFQLSIIYGLPFCGPN-VIDHFFCDMYPLLKLACTDTHVIGLLVVANGGLSCTIAFLLLLISYG-VILHSLKKLSQKGRQKAHSTCSSHITVVVFFFVPCIFMCARPART---FSI--DKSVSVFYTVITPMLNPLIYT------------------LRNSEMT-----------SAMKKL------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGL6-1", "uniprot_id": "O4A15_HUMAN", "id": "Q8NGL6-1", "name": "Olfactory receptor 4A15", "aln": "--------------------MELLTNNLKFITDPFVCRLRHLSPTPS----EEHMK-----NKNNVTEFILLGLTQNPEGQKV-LFVTFLLIYMVTIMGNLLIIVTIMASQS-LGSPMYFFLASLSFIDTVYSTAFAPKMIVDLLSEKKTISFQGCMAQLFMDHLFAGAEVILLVVMAYDRYMAICKPLHELITMNRRVCVLMLLAAWIGGFLHSLVQFLFIYQLPFCGPN-VIDNFLCDLYPLLKLACTNTYVTGLSMIANGGAICAVTFFTILLSYG-VILHSLKTQSLEGKRKAFYTCASHVTVVILFFVPCIFLYARPNST---FPI--DKSMTVVLTFITPMLNPLIYT------------------LKNAEMK-----------SAMRKLWS--------KKVSLAGKWLYHS-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NHA9-1", "uniprot_id": "O4C46_HUMAN", "id": "A6NHA9-1", "name": "Olfactory receptor 4C46", "aln": "------------------------------------------------------ME-----NRNNMTEFVLLGLTENPKMQKI-IFVVFFVIYIITVVGYVLIVVTITASPS-LGSPMYLSLAYLSFIDACYSSVNTPNLITHSLYGKKAILFNGCMTQVFGEHFFGGAEGILLTVMAYDHYVAICKPLHYMTIMNQCVCALLMGVVWMGGFLHATIQILFIFQLPFCGPN-VIDHFMCDLNPLLNLACTDTHMLELFIAANSGFICLLNFALLLVSYV-VILCSLRTHSLEARHKALSTCVSHITVVILFFVPCIFVYMRPAAT---LPI--DKAVAIFYTMITPMLNPLIYT------------------LKNAQMK-----------NAIRKLCS--------RKDISGDK------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGP0-1", "uniprot_id": "OR4CD_HUMAN", "id": "Q8NGP0-1", "name": "Olfactory receptor 4C13", "aln": "------------------------------------------------------MA-----NRNNVTEFILLGLTENPKMQKI-IFVVFSVIYINAMIGNVLIVVTITASPS-LRSPMYFFLAYLSFIDACYSSVNTPKLITDSLYENKTILFNGCMTQVFGEHFFRGVEVILLTVMAYDHYVAICKPLHYTTVMKQHVCSLLVGVSWVGGFLHATIQILFICQLPFCGPN-VIDHFMCDLYTLINLACTNTHTLGLFIAANSGFICLLNCLLLLVSCV-VILYSLKTHSLEARHEALSTCVSHITVVILSFIPCIFVYMRPPAT---LPI--DKAVAVFYTMITSMLNPLIYT------------------LRNAQMK-----------NAIRKLCS--------RKAISSVK------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96R67-1", "uniprot_id": "OR4CC_HUMAN", "id": "Q96R67-1", "name": "Olfactory receptor 4C12", "aln": "------------------------------------------------------ME-----KKKNVTEFILIGLTQNPIMEKV-TFVVFLVLYMITLSGNLLIVVTITTSQA-LSSPMYFFLTHLSLIDTVYSSSSAPKLIVDSFQEKKIISFNGCMAQAYAEHIFGATEIILLTVMACDCYVAICKPLNYTTIMSHSLCILLVAVAWVGGFLHATIQILFTVWLPFCGPN-VIGHFMCDLYPLLKLVCIDTHTLGLFVAVNSGFICLLNFLILVVSYV-IILRSLKNNSLEGRCKALSTCISHIIVVVLFFVPCIFVYLRSVTT---LPI--DKAVAVFYTMVVPMLNPVVYT------------------LRNAEVK-----------SAIRKLWR--------KKVTSDND------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH72-1", "uniprot_id": "OR4C6_HUMAN", "id": "Q8NH72-1", "name": "Olfactory receptor 4C6", "aln": "------------------------------------------------------ME-----NQNNVTEFILLGLTENLELWKI-FSAVFLVMYVATVLENLLIVVTIITSQS-LRSPMYFFLTFLSLLDVMFSSVVAPKVIVDTLSKSTTISLKGCLTQLFVEHFFGGVGIILLTVMAYDRYVAICKPLHYTIIMSPRVCCLMVGGAWVGGFMHAMIQLLFMYQIPFCGPN-IIDHFICDLFQLLTLACTDTHILGLLVTLNSGMMCVAIFLILIASYT-VILCSLKSYSSKGRHKALSTCSSHLTVVVLFFVPCIFLYMRPVVT---HPI--DKAMAVSDSIITPMLNPLIYT------------------LRNAEVK-----------SAMKKLW----------MKWEALAGK----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGB2-1", "uniprot_id": "OR4C5_HUMAN", "id": "Q8NGB2-1", "name": "Olfactory receptor 4C5", "aln": "---------------------------MYVSNCNPCAIHRKINYPNT----KLDFE-----QVNNITEFILLGLTQNAEAQKL-LFAVFTLIYFLTMVDNLIIVVTITTSPA-LDSPVYFFLSFFSFIDGCSSSTMAPKMIFDLLTEKKTISFSGCMTQLFVEHFFGGVEIILLVVMAYDCYVAICKPLYYLITMNRQVCGLLVAMAWVGGFLHALIQMLLIVWLPFCGPN-VIDHFICDLFPLLKLSCTDTHVFGLFVAANSGLMCMLIFSILITSYV-LILCSQR--------KALSTCAFHITVVVLFFVPCILVYLRPMIT---FPI--DKAVSVFYTVVTPMLNPLIYT------------------LRNTEVK-----------NAMKQLWS--------QIIWGNNLCD----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH37-1", "uniprot_id": "OR4C3_HUMAN", "id": "Q8NH37-1", "name": "Olfactory receptor 4C3", "aln": "------------------------------------------------------MD-----IPQNITEFFMLGLSQNSEVQRV-LFVVFLLIYVVTVCGNMLIVVTITSSPT-LASPVYFFLANLSFIDTFYSSSMAPKLIADSLYEGRTISYECCMAQLFGAHFLGGVEIILLTVMAYDRYVAICKPLHNTTIMTRHLCAMLVGVAWLGGFLHSLVQLLLVLWLPFCGPN-VINHFACDLYPLLEVACTNTYVIGLLVVANSGLICLLNFLMLAASYI-VILYSLRSHSADGRCKALSTCGAHFIVVALFFVPCIFTYVHPFST---LPI--DKNMALFYGILTPMLNPLIYT------------------LRNEEVK-----------NAMRKLFT--------W-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGM1-1", "uniprot_id": "OR4CF_HUMAN", "id": "Q8NGM1-1", "name": "Olfactory receptor 4C15", "aln": "------------------------------------------------------MQ-----NQSFVTEFVLLGLSQNPNVQEI-VFVVFLFVYIATVGGNMLIVVTILSSPALLVSPMYFFLGFLSFLDACFSSVITPKMIVDSLYVTKTISFEGCMMQLFAEHFFAGVEVIVLTAMAYDRYVAICKPLHYSSIMNRRLCGILMGVAWTGGLLHSMIQILFTFQLPFCGPN-VINHFMCDLYPLLELACTDTHIFGLMVVINSGFICIINFSLLLVSYA-VILLSLRTHSSEGRWKALSTCGSHIAVVILFFVPCIFVYTRPPSA---FSL--DKMAAIFYIILNPLLNPLIYT------------------FRNKEVK-----------QAMRRIWN--------RLMVVSDEKENIKL------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0RCK1-1", "uniprot_id": "M0RCK1_RAT", "id": "M0RCK1-1", "name": "Olfactory receptor", "aln": "------------------------------------------------------MQ-----NHSFVTEFILLGLSQNLNVEKM-LLCLLLFIYFATIAGNMVIVVTIMYSPALLGSPMYFFLIFLSLLDACTSSSVIPKIIIDCFSERKTISFECCMIQLFAVHFFTGAEVIVLSAMAYDRYVAICKPLHYSSIMTQRLCGILVVVSWAGGFLHSIIQVIFTLQLPFCGPN-VIDHYMCDLFPLLKLACTDTHIYIFMIFANSGAICIIIFSLLLVSYG-VILFSLRTHSSEGRCKALSTCGSHIIVVLLFFVPCILIYARPTSA---FSF--EKNVVTFMNAVTPLINPMVYT------------------FRNKEMK-----------NAIRKMWK--------RLIVISDEF-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6IEV9-1", "uniprot_id": "OR4CB_HUMAN", "id": "Q6IEV9-1", "name": "Olfactory receptor 4C11", "aln": "------------------------------------------------------MQ-----QNNSVPEFILLGLTQDPLRQKI-VFVIFLIFYMGTVVGNMLIIVTIKSSRT-LGSPMYFFLFYLSFADSCFSTSTAPRLIVDALSEKKIITYNECMTQVFALHLFGCMEIFVLILMAVDRYVAICKPLRYPTIMSQQVCIILIVLAWIGSLIHSTAQIILALRLPFCGPY-LIDHYCCDLQPLLKLACMDTYMINLLLVSNSGAICSSSFMILIISYI-VILHSLRNHSAKGKKKALSACTSHIIVVILFFGPCIFIYTRPPTT---FPM--DKMVAVFYTIGTPFLNPLIYT------------------LRNAEVK-----------NAMRKLWH--------GKIISENKG-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGL7-1", "uniprot_id": "OR4P4_HUMAN", "id": "Q8NGL7-1", "name": "Olfactory receptor 4P4", "aln": "------------------------------------------------------ME-----KSNNSTLFILLGFSQNKNIEVL-CFVLFLFCYIAIWMGNLLIMISITCTQL-IHQPMYFFLNYLSLSDLCYTSTVTPKLMVDLLAERKTISYNNCMIQLFTTHFFGGIEIFILTGMAYDRYVAICKPLHYTIIMSRQKCNTIIIVCCTGGFIHSASQFLLTIFVPFCGPN-EIDHYFCDVYPLLKLACSNIHMIGLLVIANSGLIALVTFVVLLLSYV-FILYTIRAYSAERRSKALATCSSHVIVVVLFFAPALFIYIRPVTT---FSE--DKVFALFYTIIAPMFNPLIYT------------------LRNTEMK-----------NAMRKVWC--------CQILLKRNQLF---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGB4-1", "uniprot_id": "OR4S1_HUMAN", "id": "Q8NGB4-1", "name": "Olfactory receptor 4S1", "aln": "------------------------------------------------------MG-----AKNNVTEFVLFGLFESREMQHT-CFVVFFLFHVLTVLGNLLVIITINARKT-LKSPMYFFLSQLSFADICYPSTTIPKMIADTFVEHKIISFNGCMTQLFSAHFFGGTEIFLLTAMAYDRYVAICRPLHYTAIMDCRKCGLLAGASWLAGFLHSILQTLLTVQLPFCGPN-EIDNFFCDVHPLLKLACADTYMVGLIVVANSGMISLASFFILIISYV-IILLNLRSQSSEDRRKAVSTCGSHVITVLLVLMPPMFMYIRPSTT---LAA--DKLIILFNIVMPPLLNPLIYT------------------LRNNDVK-----------NAMRKLFR--------VKRSLGEK------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGF9-1", "uniprot_id": "OR4X2_HUMAN", "id": "Q8NGF9-1", "name": "Olfactory receptor 4X2", "aln": "-----------------------------------------------------------------MTEFIFLVLSPNQEVQRV-CFVIFLFLYTAIVLGNFLIVLTVMTSRS-LGSPMYFFLSYLSFMEICYSSATAPKLISDLLAERKVISWWGCMAQLFFLHFFGGTEIFLLTVMAYDHYVAICKPLSYTTIMNWQVCTVLVGIAWVGGFMHSFAQILLIFHLLFCGPN-VINHYFCDLVPLLKLACSDTFLIGLLIVANGGTLSVISFGVLLASYM-VILLHLRTWSSEGWCKALSTCGSHFAVVILFFGPCVFNSLRPSTT---LPI--DKMVAVFYTVITAILNPVIYS------------------LRNAEMR-----------KAMKRLWI--------RTLRLNEK------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH49-1", "uniprot_id": "OR4X1_HUMAN", "id": "Q8NH49-1", "name": "Olfactory receptor 4X1", "aln": "------------------------------------------------------MV-----ATNNVTEIIFVGFSQNWSEQRV-ISVMFLLMYTAVVLGNGLIVVTILASKV-LTSPMYFFLSYLSFVEICYCSVMAPKLIFDSFIKRKVISLKGCLTQMFSLHFFGGTEAFLLMVMAYDRYVAICKPLHYMAIMNQRMCGLLVRIAWGGGLLHSVGQTFLIFQLPFCGPN-IMDHYFCDVHPVLELACADTFFISLLIITNGGSISVVSFFVLMASYL-IILHFLRSHNLEGQHKALSTCASHVTVVDLFFIPCSLVYIRPCVT---LPA--DKIVAVFYTVVTPLLNPVIYS------------------FRNAEVK-----------NAMRRFIG--------GKVI----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47893-1", "uniprot_id": "OR3A2_HUMAN", "id": "P47893-1", "name": "Olfactory receptor 3A2", "aln": "--------------------------------------------MSL----QKLMEPEAGTNRTAVAEFILLGLVQTEEMQPV-VFVLLLFAYLVTTGGNLSILAAVLVEPK-LHAPMYFFLGNLSVLDVGCITVTVPAMLGRLLSHKSTISYDACLSQLFFFHLLAGMDCFLLTAMAYDRLLAICQPLTYSTRMSQTVQRMLVAASLACAFTNALTHTVAMSTLNFCGPN-EVNHFYCDLPQLFQLSCSSTQLNELLLFAVGFIMAGTPLVLIITAYSHVAAAVLRIRSVEGRKKAFSTCGSHLTVVCLFFGRGIFNYMRLGSE---EASDKDKGVGVFNTVINPMLNPLIYS------------------LRNPDVQ-----------GALWQIFL--------GRRSLT--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47888-1", "uniprot_id": "OR3A3_HUMAN", "id": "P47888-1", "name": "Olfactory receptor 3A3", "aln": "--------------------------------------------MSL----QKLMEPEAGTNRTAVAEFILLGLVQTEEMQPV-VFVLLLFAYLVTTGGNLSILAAVLVEPK-LHAPMYFFLGNLSVLDVGCITVTVPAMLGRLLSHKSTISYDACLSQLFFFHLLAGMDCFLLTAMAYDRLLAICQPLTYSTRMSQTVQRMLVAASWACAFTNALTHTVAMSTLNFCGPN-EVNHFYCDLPQLFQLSCSSTQLNELLLFVAAAFMAVAPLVFISVSYAHVVAAVLQIRSAEGRKKAFSTCGSHLTVVGIFYGTGVFSYMRLGSV---ESSDKDKGVGVFMTVINPMLNPLIYS------------------LRNTDVQ-----------GALCQLLV--------GKRSLT--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47881-1", "uniprot_id": "OR3A1_HUMAN", "id": "P47881-1", "name": "Olfactory receptor 3A1", "aln": "------------------------------------------------------MQPESGANGTVIAEFILLGLLEAPGLQPV-VFVLFLFAYLVTVRGNLSILAAVLVEPK-LHTPMYFFLGNLSVLDVGCISVTVPSMLSRLLSRKRAVPCGACLTQLFFFHLFVGVDCFLLTAMAYDRFLAICRPLTYSTRMSQTVQRMLVAASWACAFTNALTHTVAMSTLNFCGPN-VINHFYCDLPQLFQLSCSSTQLNELLLFAVGFIMAGTPMALIVISYIHVAAAVLRIRSVEGRKKAFSTCGSHLTVVAIFYGSGIFNYMRLGST---KLSDKDKAVGIFNTVINPMLNPIIYS------------------FRNPDVQ-----------SAIWRMLT--------GRRSLA--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47883-1", "uniprot_id": "OR3A4_HUMAN", "id": "P47883-1", "name": "Putative olfactory receptor 3A4", "aln": "------------------------------------------------------MDLGNSGNDSVVTKFVLLGLTETAALQPI-LFVIFLLAYVTTIGGTLSILAAILMETK-LHSPMYFFLGNLSLPDVGCVSVTVPAMLSHFISNDRSIPYKACLSELFFFHLLAGADCFLLTIMAYDRYLAICQSLTYSSRMSWGIQQALVGMSCVFSFTNALTQTVALSPLNFCGPN-VINHFYCDLPQPFQLSCSSVHLNGQLLFVAAAFMGVAPLVLITVSYAHVAAAVLRIRSAEGRKKAFSTCSSHLTVVGIFYGTGVFSYTRLGSV---ESSDKDKGIGILNTVISPMLNPLIYWTSLLDVGCISHCSSDAGVSPGPPVQ-----------SSLCCLQFTALLSPPPGWGGLSPLNSHGL-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH94-1", "uniprot_id": "OR1L1_HUMAN", "id": "Q8NH94-1", "name": "Olfactory receptor 1L1", "aln": "MERNHNPDNCNVLNFFFADKKNKRRNFGQIVSDVGRICYSVSLSLGE----PTTMG--RNNLTR-PSEFILLGLSSRPEDQKP-LFAVFLPIYLITVIGNLLIILAIRSDTR-LQTPMYFFLSILSFVDICYVTVIIPKMLVNFLSETKTISYSECLTQMYFFLAFGNTDSYLLAAMAIDRYVAICNPFHYITIMSHRCCVLLLVLSFCIPHFHSLLHILLTNQLIFCASN-VIHHFFCDDQPVLKLSCSSHFVKEITVMTEGLAVIMTPFSCIIISYLRILITVLKIPSAAGKRKAFSTCGSHLTVVTLFYGSISYLYFQPLSN---YTV-KDQIATIIYTVLTPMLNPFIYS------------------LRNKDMK-----------QGLAKLMH--------RMKCQ---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH93-1", "uniprot_id": "OR1L3_HUMAN", "id": "Q8NH93-1", "name": "Olfactory receptor 1L3", "aln": "------------------------------------------------------MG--MSNLTR-LSEFILLGLSSRSEDQRP-LFALFLIIYLVTLMGNLLIILAIHSDPR-LQNPMYFFLSILSFADICYTTVIVPKMLVNFLSEKKTISYAECLAQMYFFLVFGNIDSYLLAAMAINRCVAICNPFHYVTVMNRRCCVLLLAFPITFSYFHSLLHVLLVNRLTFCTSN-VIHHFFCDVNPVLKLSCSSTFVNEIVAMTEGLASVMAPFVCIIISYLRILIAVLKIPSAAGKHKAFSTCSSHLTVVILFYGSISYVYLQPLSS---YTV-KDRIATINYTVLTSVLNPFIYS------------------LRNKDMK-----------RGLQKLIN--------KIKSQMSRFSTKTNKICGP-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGR8-1", "uniprot_id": "OR1L8_HUMAN", "id": "Q8NGR8-1", "name": "Olfactory receptor 1L8", "aln": "------------------------------------------------------ME--RINHTSSVSEFILLGLSSRPEDQKT-LFVLFLIVYLVTITGNLLIILAIRFNPH-LQTPMYFFLSFLSLTDICFTTSVVPKMLMNFLSEKKTISYAGCLTQMYFLYALGNSDSCLLAVMAFDRYVAVCDPFHYVTTMSHHHCVLLVAFSCSFPHLHSLLHTLLLNRLTFCDSN-VIHHFLCDLSPVLKLSCSSIFVNEIVQMTEAPIVLVTRFLCIAFSYIRILTTVLKIPSTSGKRKAFSTCGFYLTVVTLFYGSIFCVYLQPPST---YAV-KDHVATIVYTVLSSMLNPFIYS------------------LRNKDLK-----------QGLRKLMS--------KRS-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q15612-1", "uniprot_id": "OR1Q1_HUMAN", "id": "Q15612-1", "name": "Olfactory receptor 1Q1", "aln": "------------------------------------------------------MD--NSNWTS-VSHFVLLGISTHPEEQIP-LFLVFSLMYAINISGNLAIITLILSAPR-LHIPMYIFLSNLALTDICFTSTTVPKMLQIIFSPTKVISYTGCLAQTYFFICFAVMENFILAVMAYDRYIAICHPFHYTMILTRMLCVKMVVMCHALSHLHAMLHTFLIGQLIFCADN-RIPHFFCDLYALMKISCTSTYLNTLMIHTEGAVVISGALAFITASYACIILVVLRIPSAKGRWKTFSTCGSHLTVVAIFYGTLSWVYFRPLSS---YSVTKGRIITVVYTVVTPMLNPFIYS------------------LRNGDVK-----------GGFMKWMS--------RMQTFFFR------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y585-1", "uniprot_id": "OR1A2_HUMAN", "id": "Q9Y585-1", "name": "Olfactory receptor 1A2", "aln": "------------------------------------------------------MK--KENQSF-NLDFILLGVTSQQEQNNV-FFVIFLCIYPITLTGNLLIILAICADIR-LHNPMYFLLANLSLVDIIFSSVTIPKVLANHLLGSKFISFGGCLMQMYFMIALAKADSYTLAAMAYDRAVAISCPLHYTTIMSPRSCILLIAGSWVIGNTSALPHTLLTASLSFCGNQ-EVANFYCDIMPLLKLSCSDVHFN-VKMMYLGVGVFSLPLLCIIVSYVQVFSTVFQVPSTKSLFKAFCTCGSHLTVVFLYYGTTMGMYFRPLTS---YSP-KDAVITVMYVAVTPALNPFIYS------------------LRNWDMK-----------AALQKLFS--------KRISS---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9P1Q5-1", "uniprot_id": "OR1A1_HUMAN", "id": "Q9P1Q5-1", "name": "Olfactory receptor 1A1", "aln": "------------------------------------------------------MR--ENNQSS-TLEFILLGVTGQQEQEDF-FYILFLFIYPITLIGNLLIVLAICSDVR-LHNPMYFLLANLSLVDIFFSSVTIPKMLANHLLGSKSISFGGCLTQMYFMIALGNTDSYILAAMAYDRAVAISRPLHYTTIMSPRSCIWLIAGSWVIGNANALPHTLLTASLSFCGNQ-EVANFYCDITPLLKLSCSDIHFH-VKMMYLGVGIFSVPLLCIIVSYIRVFSTVFQVPSTKGVLKAFSTCGSHLTVVSLYYGTVMGTYFRPLTN---YSL-KDAVITVMYTAVTPMLNPFIYS------------------LRNRDMK-----------AALRKLFN--------KRISS---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47884-1", "uniprot_id": "OR1D4_HUMAN", "id": "P47884-1", "name": "Olfactory receptor 1D4", "aln": "------------------------------------------------------MD--GDNQSE-NSQFLLLGISESPEQQQI-LFWMFLSMYLVTVLGNVLIILAISSDSH-LHTPMYFFLANLSFTDLFFVTNTIPKMLVNFQSQNKAISYAGCLTQLYFLVSLVTLDNLILAVMAYDRYVAICCPLHYVTAMSPGLCVLLLSLCWGLSVLYGLLLTFLLTRVTFCGPR-EIHYLFCDMYILLWLACSNTHIIHTALIATGCFIFLTLLGFMTTSYVRIVRTILQMPSASKKYKTFSTCASHLGVVSLFYGTLAMVYLQPLHT---YSM-KDSVATVMYAVLTPMMNPFIYS------------------LRNKDMH-----------GAPGRVLW--------RPFQRP--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P58170-1", "uniprot_id": "OR1D5_HUMAN", "id": "P58170-1", "name": "Olfactory receptor 1D5", "aln": "------------------------------------------------------MD--GDNQSE-NSQFLLLGISESPEQQRI-LFWMFLSMYLVTVLGNVLIILAISSDSH-LHTPMYFFLANLSFTDLFFVTNTIPKMLVNFQSQNKAISYAGCLTQLYFLVSLVTLDNLILAVMAYDRYVATCCPLHYVTAMSPGLCVLLLSLCWGLSVLYGLLLTFLLTRVTFCGPR-EIHYLFCDMYILLWLACSNTHIIHTALIATGCFIFLTPLGFMTTSYVRIVRTILQMPSASKKYKTFSTCASHLGVVSLFYGTLAMVYLQPLHT---YSM-KDSVATVMYAVLTPMMNPFIYR------------------LRNKDMH-----------GAPGRVLW--------RPFQRPK-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZL22-1", "uniprot_id": "D3ZL22_RAT", "id": "D3ZL22-1", "name": "Olfactory receptor", "aln": "------------------------------------------------------MSKWGENETG-VIEFLLLGITNDPQQQRI-LFWAFLCMYLVTVAGNTLIFLAISSDPH-LHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLG-AVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDS---FST-QDTVATIMFTVVTPMLNPFIYS------------------LRNKDMK-----------ETVTRLLH--------RGSKSS--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4AB86-1", "uniprot_id": "D4AB86_RAT", "id": "D4AB86-1", "name": "Olfactory receptor", "aln": "------------------------------------------------------MSKWGENETR-ASGFLLLGITNDPQQQQI-LFWAFLCMYLVTVAGNTLIFLAISSDPR-LHTPMYFFLANLSFVDVCFTTNLIPRLLASHVSGTEIISYAHCLTQMYFLISFANVDTFLLAAMALDRFVAICYPLQYHTIITPQLCVGLAAVVWICSGLISLVHTLLMNRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLG-AVVLFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDS---FST-QDTVATIMYTVVTPMLNPFIYS------------------LRNKDMK-----------QTVTRLFN--------RGSQSS--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZPR8-1", "uniprot_id": "A0A8I5ZPR8_RAT", "id": "A0A8I5ZPR8-1", "name": "Olfactory receptor", "aln": "------------------------------------------------------MSKWGENETG-VSEFLLLGITNDPQQQRI-LFWAFLCMYLVTVAGNTLIFMAISSDPR-LHTPMYFFLANLSFNEVCFTTNLIPRLLASHVSGIGTISYAHCLTQMYFLISFADVDFCLLTAMALDRFVAICYPLQYHTIITPRLCVGLAAVVWISCGLIALVHTLFMSRLTFCSSIPEISHFYCDPYLLMKLACSDTRVDQLLFLG-AVVLFVAPCILIVFSYARIAVAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDS---FST-QDTVATIMYTVVTPMLNPFIYS------------------LRNKDMK-----------ETVTRLLH--------RCSKSS--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VFM8-1", "uniprot_id": "Q8VFM8_MOUSE", "id": "Q8VFM8-1", "name": "Olfactory receptor", "aln": "------------------------------------------------------ME--SKNQTD-VSEFFLMGITDDIALKPL-IFSMFTSMYLITILGNLLIILTVCSDSH-LQTPMYIFLSNLSFNDICLSTTIIPKTLVNIHAQDQSITYTSCLTQICFTLLFCSFESCLLSVMAYDRYVAICHPLNYTTIMNPQTCGLLILLSLIISLVNSGLLGLMVLRLSFCTNL-EIPLFFCELAQVIKLACSDTLVNYILIYLATIILNGIPISGIIFSYTQIASSVLRMSSVKGKYKAISTCGSHLSVVSLFYGTALGVYISSSFT---TSVTNTAFAYVMCTLVPQMLNPFIYS------------------LRNRDME-----------VALRKHIN--------RAMCLL--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2R8YED5-1", "uniprot_id": "O5BS1_HUMAN", "id": "A0A2R8YED5-1", "name": "Olfactory receptor 5BS1", "aln": "------------------------------------------------------MEVS---NMTTVTVFILLGLSNNPQVQAL-LFVLFLVIYLLTLLGNLLMVLVISTDSH-LCTPMYFFLRQLSFLDAFYSSIIVPKLLENLLSKGETISFLECFTQISLVIFSGATEACLLSVMAYDRFQAMCHPLLYVVIINRRVCAGLVGASWAIGMGTGLINTLLLAQQHFCGPN-VIHSFACELPPVLLLTCSDPCASIVSILTTMSVLGLGTLVLLLGSYSCIIMTALRINSATGRSKIFSTCSSHFLVVTIFYTSGVLRYMIPASG---SAL--EQVLSVQYSVITPLLNPLIYS------------------LKSQEVK-----------VALRRMLA--------RKSR----------------LPL---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH09-1", "uniprot_id": "OR8S1_HUMAN", "id": "Q8NH09-1", "name": "Olfactory receptor 8S1", "aln": "------------------------------------------------------MALG---NHSTITEFLLLGLSADPNIRAL-LFVLFLGIYLLTIMENLMLLLMIRADSC-LHKPMYFFLSHLSFVDLCFSSVIVPKMLENLLSQRKTISVEGCLAQVFFVFVTAGTEACLLSGMAYDRHAAICRPLLYGQIMGKQLYMHLVWGSWGLGFLDALINVLLAVNMVFCEAK-IIHHYSYEMPSLLPLSCSDISRSLIALLCSTLLHGLGNFLLVFLSYTRIISTILSISSTSGRSKAFSTCSAHLTAVTLYYGSGLLRHLMPNSG---SPI--ELIFSVQYTVVTPMLNSLIYS------------------LKNKEVKGERSLRDSSHLPQLHKGQA--------RWKRPAFTEGRREPGHPELSIPVTPQPQGACACSALRAAPTALP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IF42-1", "uniprot_id": "OR2A2_HUMAN", "id": "Q6IF42-1", "name": "Olfactory receptor 2A2", "aln": "--------------------------------------------------ME--------GNQTWITDITLLGFQVGPALAIL-LCGLFSVFYTLTLLGNGVIFGIICLDSK-LHTPMYFFLSHLAIIDMSYASNNVPKMLANLMNQKRTISFVPCIMQTFLYLAFAVTECLILVVMSYDRYVAICHPFQYTVIMSWRVCTILVLTSWSCGFALSLVHEILLLRLPFCGPR-DVNHLFCEILSVLKLACADTWVNQVVIFATCVFVLVGPLSLILVSYMHILGAILKIQTKEGRIKAFSTCSSHLCVVGLFFGIAMVVYMVPDSN---QREEQEKMLSLFHSVFNPMLNPLIYS------------------LRNAQLK-----------GALHRALQ--------RKRSMRTVYGLCL-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96R47-1", "uniprot_id": "O2A14_HUMAN", "id": "Q96R47-1", "name": "Olfactory receptor 2A14", "aln": "--------------------------------------------------ME--------GNKTWITDITLPRFQVGPALEIL-LCGLFSAFYTLTLLGNGVIFGIICLDCK-LHTPMYFFLSHLAIVDISYASNYVPKMLTNLMNQESTISFFPCIMQTFLYLAFAHVECLILVVMSYDRYADICHPLRYNSLMSWRVCTVLAVASWVFSFLLALVPLVLILSLPFCGPH-EINHFFCEILSVLKLACADTWLNQVVIFAACVFILVGPLCLVLVSYLRILAAILRIQSGEGRRKAFSTCSSHLCVVGLFFGSAIVTYMAPKSR---HPEEQQKVLSLFYSLFNPMLNPLIYS------------------LRNAEVK-----------GALRRALR--------KERLT---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGT9-1", "uniprot_id": "OR2A1_HUMAN", "id": "Q8NGT9-1", "name": "Olfactory receptor 2A1/2A42", "aln": "--------------------------------------------------MG--------ENQTMVTEFLLLGFLLGPRIQML-LFGLFSLFYIFTLLGNGAILGLISLDSR-LHTPMYFFLSHLAVVDIAYTRNTVPQMLANLLHPAKPISFAGCMTQTFLCLSFGHSECLLLVLMSYDRYVAICHPLRYSVIMTWRVCITLAVTSWTCGSLLALAHVVLILRLPFSGPH-EINHFFCEILSVLRLACADTWLNQVVIFAACVFFLVGPPSLVLVSYSHILAAILRIQSGEGRRKAFSTCSSHLCVVGLFFGSAIIMYMAPKSR---HPEEQQKVFFLFYSFFNPTLNPLIYS------------------LRNGEVK-----------GALRRALG--------KESHS---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGY7-1", "uniprot_id": "O10J6_HUMAN", "id": "Q8NGY7-1", "name": "Putative olfactory receptor 10J6", "aln": "--------------------------------------------------MRR-------KNLTEVTEFVFLGFSRFHKHHIT-LFVVFLILYTLTVAGNAIIMTIICIDRH-LHTPMYFFLSMLASSKTVYTLFIIPQMLSSFVTQTQPISLAGCTTQTFFFVTLAINNCFLLTVMGYDHYMAICNPLRYRVITSKKVCVQLVCGAFSIGLAMAAVQVTSIFTLPFCHT--VVGHFFCDILPVMKLSCINTTINEIINFVVRLFVILVPMGLVFISYVLIISTVLKIASAEGWKKTFATCAFHLTVVIVHYGCASIAYLMPKSE---NSIEQDLLLSVT--------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGX8-1", "uniprot_id": "OR6Y1_HUMAN", "id": "Q8NGX8-1", "name": "Olfactory receptor 6Y1", "aln": "---------------------------------------------MTTIILEV-------DNHTVTTRFILLGFPTRPAFQLL-FFSIFLATYLLTLLENLLIILAIHSDGQ-LHKPMYFFLSHLSFLEMWYVTVISPKMLVDFLSHDKSISFNGCMTQLYFFVTFVCTEYILLAIMAFDRYVAICNPLRYPVIMTNQLCGTLAGGCWFCGLMTAMIKMVFIAQLHYCGMP-QINHYFCDISPLLNVSCEDASQAEMVDFFLALMVIAIPLCVVVASYAAILATILRIPSAQGRQKAFSTCASHLTVVILFYSMTLFTYARPKLM---YAYNSNKVVSVLYTVIVPLLNPIIYC------------------LRNHEVK-----------AALRKTIH--------CRGSGPQGNGAFSS------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VFD8-1", "uniprot_id": "Q8VFD8_MOUSE", "id": "Q8VFD8-1", "name": "Olfactory receptor", "aln": "------------------------------------------------------MSG---VSENQTTWLTLVGFGKLKHLGFL-PFALFLAIYVATVGGNILIVLAVASSRT-LHTPMYFFLCHFSLLEIGYTSNIVPRLLQSFLEGGDLISLVGCLAQFYVFASLAAAECLMLSAMSYDRYLAICHPLHYPVLMSTWCCVRLATGAWFSGFFFSAFTLALAAPLSLCPGRRVIDHYFCDFAPVVGLFCGEVWVMWGAGVSISGCLTLAPFLLIVASYVFILRAVLRIPSSHGRQKAFSTCSSHLSVVAVFYGTLIVVYVAPTEH---MPALLRKAFSVFYTVLTPMFNPIIYS------------------LKNQEVK-----------WALRRLCR--------QLL-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NND4-1", "uniprot_id": "O2AT4_HUMAN", "id": "A6NND4-1", "name": "Olfactory receptor 2AT4", "aln": "-----------------------------------------------------MDATACNESVDGSPVFYLLGIPSLPETFFLPVFFIFLLFYLLILMGNALILVAVVAEPS-LHKPMYFFLINLSTLDILFTTTTVPKMLSLFLLGDRFLSFSSCLLQMYLFQSFTCSEAFILVVMAYDRYVAICHPLHYPVLMNPQTNATLAASAWLTALLLPIPAVVRTSQMAYNSIA-YIYHCFCDHLAVVQASCSDTTPQTLMGFCIAMVVSFLPLLLVLLSYVHILASVLRISSLEGRAKAFSTCSSHLLVVGTYYSSIAIAYVAYRAD---LPLDFHIMGNVVYAILTPILNPLIYT------------------LRNRDVK-----------AAITKIMS--------QDPGCDRSI-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2PRB3-1", "uniprot_id": "Q2PRB3_DANRE", "id": "Q2PRB3-1", "name": "", "aln": "---------------------------------------------------------MTFTNVTVFTEFYLLGFPELHPDYYGAVGTLFLFVYLTLLGGNIFIIAFIAYEKS-LQKPTYVIFCNLAVCDLTFGTVVLPQAIAMYFININTISFSRCFVQMFFVHYLGSVSSLIILIMTIDRIVAIQNPFRYCVLITNKTIFIACGVIWTAITPLMAIIVYEAYDEPYCATN-VVTQIFCERNVVIKLSCRDVRQKLLLTLAWAMIVVLGPSLFVLFSFIAIFMFVFNISDNQTRYKTLSTCTPQLFIICLYFVPKFVLYVYDITVA--LSPSFRIALSLCFCLLPPVVNPMIYC------------------FKTKEIK-----------DALKMKIR---------HASVNQVIL----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : : : : . * : : : : * : .: . * . : : : : ", "identical_positions": 3, "similar_positions": 21, "identity": "0.67%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010308-11", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TQQ0-1", "uniprot_id": "OR4E2_MOUSE", "id": "Q7TQQ0-1", "name": "Olfactory receptor 4E2", "aln": "----------------------------------------MGALNQT-RVTEFIFLGLTDNWVLEILFFVPFTVTYMLTLLGNFLIVVTIVFTPRLHNPMYFFLSNLSFIDICHSSVTVPKMLEGLLLERKTISFDNCIAQLFFLHLFACSEIFLLTIMAYDRYVAICIP---------LHYSNVMNMKVCVQLVFALWLGGTIHSLVQTFLTIRLPYCGPNIIDSYFCDVPPVIKLACTDTYLTGILIVSNSGTISLVCFLALVTS--YTVILFSLRKQSAEGRRKALSTCSAHFMVVA--LFFGPCIFLYTRP----DSSFS---IDKVVSVFYTVVTPLLNPLIYTLRNEEVKTAMKHLRQRRICS--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ADC0-1", "uniprot_id": "D4ADC0_RAT", "id": "D4ADC0-1", "name": "Olfactory receptor", "aln": "----------------------------------------MGALNQT-RVTEFVFLGLTDNWVLEILFFIPFTVTYVLTLLGNVLIVVTIVFTPRLHNPMYFFLSNLSFIDICHSSVTVPKMLEGLLLVRKTISFDNCIAQLFFLHLFACAEIFLLTIMAYDRYVAICIP---------LHYPNVMNMKVCVQLVFALWLGGTVHSLVQTFLTIRLPYCGPNTIDSYFCDVPPVIKLACTDTYLTGILIVSNSGTISLVCFLALVTS--YTVILFSLRKQSAEGRRKALSTCSAHFMVVA--LFFGPCIFIYTWP----DTSFS---IDKVVSVFYTVVTPLLNPLIYTLRNEEVKTSMKHLRQRRICS--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGC2-1", "uniprot_id": "OR4E2_HUMAN", "id": "Q8NGC2-1", "name": "Olfactory receptor 4E2", "aln": "----------------------------------------MDSLNQT-RVTEFVFLGLTDNRVLEMLFFMAFSAIYMLTLSGNILIIIATVFTPSLHTPMYFFLSNLSFIDICHSSVTVPKMLEGLLLERKTISFDNCITQLFFLHLFACAEIFLLIIVAYDRYVAICTP---------LHYPNVMNMRVCIQLVFALWLGGTVHSLGQTFLTIRLPYCGPNIIDSYFCDVPLVIKLACTDTYLTGILIVTNSGTISLSCFLAVVTS--YMVILVSLRKHSAEGRQKALSTCSAHFMVVA--LFFGPCIFIYTRP----DTSFS---IDKVVSVFYTVVTPLLNPFIYTLRNEEVKSAMKQLRQRQVFFTKSYT---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R0K4-1", "uniprot_id": "Q9R0K4_MOUSE", "id": "Q9R0K4-1", "name": "Olfactory receptor", "aln": "-------------------------------------MEKAVLINETSVMS-FRLTGLSTNPLVQMAVFFIFLIFYVLTLVGNILIVITIIYDRRLHTPMYFFLSNLSFIDVCHSTVTVPKMLSDTFSEEKLISFDACVVQMFFLHLFACTEIFLLTVMAYDRYVAICKP---------LQYMTIMNWKVCMMLAAALWTGGTIHSISLTSLTIKLPYCGPDEIDNFFCDVPQVIKLACTDTHIIEILIVSNSGLISVVCFVVLVVS--YAVILVSLRQQISDGKRKALSTCAAHLTVVT--LFLGHCIFIYSRP----STSLP---EDKVVSVFFTAVTPLLNPIIYTLRNEDMKSALNKLIKRREK---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C645-1", "uniprot_id": "OR4E1_HUMAN", "id": "P0C645-1", "name": "Olfactory receptor 4E1", "aln": "-------------------------------------MEEAILLNQTSLVTYFRLRGLSVNHKARIAMFSMFLIFYVLTLIGNVLIVITIIYDHRLHTPMYFFLSNLSFIDVCHSTVTVPKMLRDVWSEEKLISFDACVTQMFFLHLFACTEIFLLTVMAYDRYVAICKP---------LQYMIVMNWKVCVLLAVALWTGGTIHSIALTSLTIKLPYCGPDEIDNFFCDVPQVIKLACIDTHVIEILIVSNSGLISVVCFVVLVVS--YAVILVSLRQQISKGKRKALSTCAAHLTVVT--LFLGHCIFIYSRP----STSLP---EDKVVSVFFTAVTPLLNPIIYTLRNEEMKSALNKLVGRKERKEEK-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2I3BQG5-1", "uniprot_id": "A0A2I3BQG5_MOUSE", "id": "A0A2I3BQG5-1", "name": "Olfactory receptor", "aln": "----------------------------MSAPTSVYQGSNSVLLNQT-LVTEFLLLGVTDIQELNPILFVTVLAMYFVNVAGNGAILLIVISDPRLHSPMYFFLGNLACLDICFSTVTVPKILDNFFSTSKAISFLGCITQLYFFHLLGSTEALLLAVMAFDRFVAICRP---------LHYPSIMNGQVCIQVAISIWAIPFVHALVHSILTSQLNFCGSNQIHHFFCDVKPLLELACGNTELNRWLLNTFTGTFAIGLFFLTFLSYFYIITYLFLKTRSCSMLHKALSTCASHFMVVM--IFYAPVLFIYINP--DSGSSLE---KDRIIAVMYTVVTPALNPLIYTLRNKEVRGALNRKLRILL----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2I3BRX0-1", "uniprot_id": "A0A2I3BRX0_MOUSE", "id": "A0A2I3BRX0-1", "name": "Olfactory receptor", "aln": "----------------------------MSAPTSVSQEGNSVLLNHT-LVTEFLLLGVTDIQELNPILFVTVLAMYFVNVAGNGAILMIVISDPRLHLPMYFFLGNLACLDICFSTVTVPKMLENFFSTSKAISFLGCITQLHFFHFLGSTEALLLTVMAFDRFVAICRP---------LHYPAIMNSQVCIQVAISIWAIPFLHALVHSILTSQLNFCGSNHIHHFFCDVKPLLELACGNTELNRWLLNTLTGTVAIGLFFLTFLSYFYIVTYLFLKTRSCSMLHKALSTCASHFMVVM--IFYAPVLFIYINP--DSGSSLE---KDRIIAVMYTVVTPALNPLIYTLRNKEVRGALNRKIRILL----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58182-1", "uniprot_id": "O12D2_HUMAN", "id": "P58182-1", "name": "Olfactory receptor 12D2", "aln": "------------------------------------------MLNTT-SVTEFLLLGVTDIQELQPFLFVVFLTIYFISVTGNGAVLMIVISDPRLHSLMYFFLGNLSYLDICYSTVTLPKMLQNFLSTHKAISFLGCISQLHFFHSLGSTESMLFAVMAFDLSVAICKP---------LRYTVIMNPQLCTQMAITIWVIGFFHALLHSVMTSRLNFCGSNRIHHFLCDIKPLLKLACGNTELNQWLLSTVTGTIAMGPFFLTLLSYFYIITYLFFKTRSCSMLCKALSTCASHFMVVI--LFYAPVLFTYIHP--ALESFMD---QDRIVAIMYTVVTPVLNPLIYTLRNKEVKGALGRVIRRL-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VG96-1", "uniprot_id": "Q8VG96_MOUSE", "id": "Q8VG96-1", "name": "Olfactory receptor", "aln": "------------------------------------------MENST-SVDEFLLLGLTSVQKLQPIIFVMFLTIYLLNLVGNGVILMIVTLERRLHSPMYFFLGNLSCLDICYSSVTLPKVLINLLSRRRAISFLGCITQLYFFHFLGSTEAILLAVMAFDRFVAICSP---------LRYTAIMNPQLCILLAATAWFTSFFYALLHSVMTAHLNFCHSHKLSHFFCDVKPLLEVACGNTVLNQWLLSVVTGSISMGAFLLILLSYFYIIAFLLFKNRSCRMLKKALSTCTSHFMVVC--LFYGPVGFTYIRPATASASSMS---EDRVVAIIYSAVTPVLNPLIYTLRNKEVMLALKKNFGKKLFKGN------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGF7-1", "uniprot_id": "O12D3_HUMAN", "id": "Q9UGF7-1", "name": "Olfactory receptor 12D3", "aln": "------------------------------------------MENVT-TMNEFLLLGLTGVQELQPFFFGIFLIIYLINLIGNGSILVMVVLEPQLHSPMYFFLGNLSCLDISYSSVTLPKLLVNLVCSRRAISFLGCITQLHFFHFLGSTEAILLAIMAFDRFVAICNP---------LRYTVIMNPQVCILLAAAAWLISFFYALMHSVMTAHLSFCGSQKLNHFFYDVKPLLELACSDTLLNQWLLSIVTGSISMGAFFLTLLSCFYVIGFLLFKNRSCRILHKALSTCASHFMVVC--LFYGPVGFTYIRP--ASATSMI---QDRIMAIMYSAVTPVLNPLIYTLRNKEVMMALKKIFGRKLFKDWQQHH--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VGK1-1", "uniprot_id": "Q8VGK1_MOUSE", "id": "Q8VGK1-1", "name": "Olfactory receptor", "aln": "-------------------------------------ME-----NES-SVSEFFLQGISGFSEQQQLLYGLFLCMYLVTLTGNVLIILAIGSDPHLHTPMYFFLANLSFADMGLISSTVTKMLFNVQTRCHTISYTGCLTQMYFFLMFGDLDSFLLAVMAYDRYVAICHP---------LHYSTIMSARVCALMLALCWVLTNIVALTHTLLMARLSFCVVGEIAHFFCDITPVLKLSCSDTHVNELMVFALGGTVLMVPFVCIVISYIHIVFAI-LKVRTPGGGTKAFSTCSSHLCVVC--VFYGTLFSAYLCP--PSVVST---EKDVAAAAMYTVVTPMLNPFIYSLRNKDMKGALKRLLCHRKFLS-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGK0-1", "uniprot_id": "Q8VGK0_MOUSE", "id": "Q8VGK0-1", "name": "Olfactory receptor", "aln": "-------------------------------------ME-----NQS-SVSEFFLRGISGFPEQQQLLYGLFLCMYLVTLTGNVLIILAISCDPHLHTPMYFFLANLSFADMGLISSAVTKMLFNVQTQRHTISYTGCLTQMYLFMMFGDLDSFFLAVMAYDRYVAICHP---------LHYSTIMSARVCALMLALCWVLTNIVALTHTLLMTRLSFCVVGEIAHFFCDITSVMKLSCSDTHVNELVLSGFGGTVLMVPFVSIVISYVRIVFAV-LRVQTSGGSSKAFSTCSSHLCVVC--VFYGTLFSVYLFP--SSGETT---EKDVVAAAMYTVVTPMLNPFIYSLRNKDMKGALKRLLCHRRKFSP------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGS0-1", "uniprot_id": "OR1N1_HUMAN", "id": "Q8NGS0-1", "name": "Olfactory receptor 1N1", "aln": "-------------------------------------ME-----NQS-SISEFFLRGISAPPEQQQSLFGIFLCMYLVTLTGNLLIILAIGSDLHLHTPMYFFLANLSFVDMGLTSSTVTKMLVNIQTRHHTISYTGCLTQMYFFLMFGDLDSFFLAAMAYDRYVAICHP---------LCYSTVMRPQVCALMLALCWVLTNIVALTHTFLMARLSFCVTGEIAHFFCDITPVLKLSCSDTHINEMMVFVLGGTVLIVPFLCIVTSYIHIVPAI-LRVRTRGGVGKAFSTCSSHLCVVC--VFYGTLFSAYLCP--PSIASE---EKDIAAAAMYTIVTPMLNPFIYSLRNKDMKGALKRLFSHRSIVSS------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VGJ8-1", "uniprot_id": "Q8VGJ8_MOUSE", "id": "Q8VGJ8-1", "name": "Olfactory receptor", "aln": "-------------------------------------MGKISRVNQS-VASDFLLLGLSEQPGEQPLLFGIFLGMYLVTMVGNLLIIFVISSDAHLHTPMYFFLANLSLTDACFTSASVPKMLANIYTQSQTISYSGCLTQLYFLLMFGGLDNCLLAVMAYDRYVAICQP---------LHYSTAMSPQLCALMLCTCWVLTNCPALMHTLLLTRVAFCAHTAIPHFYCDPSALLKLACSDTHINELMIITMGLVFLAVPLMLIVFSYVCISWAV-LGIPSSGGRWKAFSTCGSHLTVVL--LFYGSLMGVYLLP--PSTHST---ERESRAAVLYMIVIPMLNPFIYSLRNRDMKEAMGKLFGGGKTVFLL-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGR9-1", "uniprot_id": "OR1N2_HUMAN", "id": "Q8NGR9-1", "name": "Olfactory receptor 1N2", "aln": "-------------------------------------MGKPGRVNQT-TVSDFLLLGLSEWPEEQPLLFGIFLGMYLVTMVGNLLIILAISSDPHLHTPMYFFLANLSLTDACFTSASIPKMLANIHTQSQIISYSGCLAQLYFLLMFGGLDNCLLAVMAYDRYVAICQP---------LHYSTSMSPQLCALMLGVCWVLTNCPALMHTLLLTRVAFCAQKAIPHFYCDPSALLKLACSDTHVNELMIITMGLLFLTVPLLLIVFSYVRIFWAV-FVISSPGGRWKAFSTCGSHLTVVL--LFYGSLMGVYLLP--PSTYST---ERESRAAVLYMVIIPTLNPFIYSLRNRDMKEALGKLFVSGKTFFL------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TQU7-1", "uniprot_id": "Q7TQU7_MOUSE", "id": "Q7TQU7-1", "name": "", "aln": "-------------------------------------MAP---ENQT-TVLEFHLMGLSEDPDLQTILFGLFLSMYLVTVFGNLLIILAIISDSHLHTPMYFFLCNLSLVDIFFCSTTVPKMLVNIQTQSRAISFTGCLVQMYAFHLFGTIDSFLLAVMAIDRLVAIAYP---------LRYSVLMSPHVCALLVGGTWVITNLQSLVHTCLMAQLTFCARSEIPHFFCDLMPLLKLSCSDTHINELVIFAFGIVMGLSPLSCILVSYICIFRAV-FRIPSAQGKWKAFSTCGSHLTVVS--LFYGTIFTGYLLP--ASPSSS---QKDKAAALMFGVVIPTLNPFIYSLRNKDMKAALRKLGSKAVS----------------------------------FQS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60431-1", "uniprot_id": "OR1I1_HUMAN", "id": "O60431-1", "name": "Olfactory receptor 1I1", "aln": "-------------------------------------MEP---EKQT-EISEFFLQGLSEKPEHQTLLFTMFLSTYLVTIIGNALIILAIITDSHLHTPMYFFLFNLSLVDTLLSSTTVPKMLANIQAQSRAIPFVGCLTQMYAFHLFGTMDSFLLAVMAIDRFVAIVHP---------QRYLVLMCSPVCGLLLGASWMITNLQSLIHTCLMAQLTFCAGSEISHFFCDLMPLLKLSGSDTHTNELVIFAFGIVVGTSPFSCILLSYIRIFWTV-FKIPSTRGKWKAFSTCGLHLTVVS--LSYGTIFAVYLQP--TSPSSS---QKDKAAALMCGVFIPMLNPFIYSIRNKDMKAALGKLIGKVAVPCPRPEQLLDVYHVPGSLLAARDTEMHPIPYPGGVQSLAGNRDME", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH06-1", "uniprot_id": "OR1P1_HUMAN", "id": "Q8NH06-1", "name": "Olfactory receptor 1P1", "aln": "--------------------------MGLTQDFFPPTSELLEGGNQT-STFEFLLWGLSDQPQQQHIFFLLFLWMYVVTVAGNLLIVLAIGTDTHLHTPMYFFLASLSCADIFSTSTTVPKALVNIQTQSRSISYAGCLAQLYFFLTFGDMDIFLPATMAYDRYVAICHL---------LHYMMIMSLHRCAFLVTACWTLTSLLAMTRTFLIFRLSLCSK-ILPGFFCDLGPLMKVSCSDAQVNELVLLFLGGAVILIPFMLILVSYIRIVSAI-LRAPSAQGRRKAFSTCDSHLVVVA--LFFGTVIRAYLCP--SSSSSNS-VKEDTAAAVMYTVVTPLLNPFIYSMRNKDMKAAVVRLLKGRVSFSQGQ----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGA1-1", "uniprot_id": "OR1M1_HUMAN", "id": "Q8NGA1-1", "name": "Olfactory receptor 1M1", "aln": "-------------------------------------MEP---RNQT-SASQFILLGLSEKPEQETLLFSLFFCMYLVMVVGNLLIILAISIDSHLHTPMYFFLANLSLVDFCLATNTIPKMLVSLQTGSKAISYPCCLIQMYFFHFFGIVDSVIIAMMAYDRFVAICHP---------LHYAKIMSLRLCRLLVGALWAFSCFISLTHILLMARLVFCGSHEVPHYFCDLTPILRLSCTDTSVNRIFILIVAGMVIATPFVCILASYARILVAI-MKVPSAGGRKKAFSTCSSHLSVVA--LFYGTTIGVYLCP--SSVLTT---VKEKASAVMYTAVTPMLNPFIYSLRNRDLKGALRKLVNRKITSSS------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VFM9-1", "uniprot_id": "OR1M1_MOUSE", "id": "Q8VFM9-1", "name": "Olfactory receptor 1M1", "aln": "-------------------------------------MEP---QNHT-SASEFILLGLSEKPDHDPVLFSLFLCMYMITVVGNLLIILAISFDSHLHTPMYFFLANLSLVDFCLATNTVPKMLVNIQTRNKSISYPCCLTQMYFFHFFGIMDSVLIAVMAYDRFVAICHP---------LHYSTIMSPRLCGLLVGVPWVYSCFISLTHILLMARLVFCGKNELPHYFCDLTPLLRLSCTDTTVNKIFVLIVAGMVIATPFVCILASYARIIVAI-MKVPSAGGRKKAFSTCSSHLSVVA--LFYGTTIGVYLCP--SSVRTA---VKEKASAVMYTAVTPMLNPFIYSLRNRDLKGALKKIINRKISTSS------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGG9-1", "uniprot_id": "Q8VGG9_MOUSE", "id": "Q8VGG9-1", "name": "Olfactory receptor", "aln": "-------------------------------------MDG---DNQT-IVTEFILLGLTRQSEKEEVVFGLFLWMYLVTISGNLLIILAISCDPHLHTPMYFFLANLSSVDISAPSVIVPKALVNHMLGSKSISYTGCMTQIYFFITFSNMDGFLLSVMAYDRYVAICHP---------LHYTMMMRPRLCVLLVAISWAITNLHALLHTLLMVRLTFCSHNAVHHFFCDPYPILKLSCSDTFINDLMVFTIGGLVFMTPFTCIIVSYAYIFSKV-LKLKSAHGIRKALSTCGSHLTVVS--LFYGAILGIYMHP--SSTYTVQ----DTVATVIFTVVTPMVNPFIYSLRNRDIKGALRKIILRS-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGH1-1", "uniprot_id": "Q8VGH1_MOUSE", "id": "Q8VGH1-1", "name": "Olfactory receptor", "aln": "-------------------------------------MDG---DNET-MVAEFLLLGLSGKSEQEEVVFGMFLGMYLVTISGNLLIILAISCDPHLHTPMYFFLANLSSVDICFSSVTVPKALVNHVLGSKSISYTECMIQIYFFITFINMDGFLLSVMAYDRYVAICHP---------LHYTMMMRSRLCVLLVAISWVITNLHALLHTLLMVRLTFCSHNAVHHFFCDPYPILKLSCSDTFINDLMVFTVGGVIFLTPFSCIVVSYVYIFSKV-LKIPSARGIRKALSTCGSHLTVVS--LFYGAILGVYMRP--SSSYSLQ----DTVATVIFTVVTPLVNPFIYSLRNQDMKGALRKIMLRS-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NHA8-1", "uniprot_id": "OR1FC_HUMAN", "id": "Q8NHA8-1", "name": "Putative olfactory receptor 1F12P", "aln": "-------------------------------------MEG---KNQT-NISEFLLLGFSSWQQQQVLLFALFLCLYLTGLFGNLLILLAIGSDHCLHTPMYFFLANLSLVDLCLPSATVPKMLLNIQTQTQTISYPGCLAQMYFCMMFANMDNFLLTVMAYDRYVAICHP---------LHYSTIMALRLCASLVAAPWVIAILNPLLHTLMMAHLHFCSDNVIHHFFCDINSLLPLSCSDTSLNQLSVLATVGLIFVVPSVCILVSYILIVSAV-MKVPSAQGKLKAFSTCGSHLALVI--LFYGAITGVYMSP--LSNHSTEK---DSAASVIFMVVAPVLNPFIYSLRNNELKGTLKKTLSRPGAVAHACNPSTLGGRGGWIMRSGDRDHPG------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P30953-1", "uniprot_id": "OR1E1_HUMAN", "id": "P30953-1", "name": "Olfactory receptor 1E1", "aln": "-------------------------------------MMG---QNQT-SISDFLLLGLPIQPEQQNLCYALFLAMYLTTLLGNLLIIVLIRLDSHLHTPMYLFLSNLSFSDLCFSSVTIPKLLQNMQNQDPSIPYADCLTQMYFFLLFGDLESFLLVAMAYDRYVAICFP---------LHYTAIMSPMLCLALVALSWVLTTFHAMLHTLLMARLCFCADNVIPHFFCDMSALLKLAFSDTRVNEWVIFIMGGLILVIPFLLILGSYARIVSSI-LKVPSSKGICKAFSTCGSHLSVVS--LFYGTVIGLYLCS--SANSST---LKDTVMAMMYTVVTPMLNPFIYSLRNRDMKGALSRVIHQKKTFFSL-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47887-1", "uniprot_id": "OR1E2_HUMAN", "id": "P47887-1", "name": "Olfactory receptor 1E2", "aln": "-------------------------------------MMG---QNQT-SISDFLLLGLPIQPEQQNLCYALFLAMYLTTLLGNLLIIVLIRLDSHLHTPVYLFLSNLSFSDLCFSSVTMPKLLQNMQNQDPSIPYADCLTQMYFFLYFSDLESFLLVAMAYDRYVAICFPMHYTAICFLLHYTAIMSPMLCLSVVALSWVLTTFHAMLHTLLMARLCFCADNVIPHFFCDMSALLKLACSDTRVNEWVIFIMGGLILVIPFLLILGSYARIVSSI-LKVPSSKGICKAFSTCGSHLSVVS--LFYGTVIGLYLCP--SANSST---LKDTVMAMMYTVVTPMLTPFIYSLRNRDMKGALERVICKRKNPFLL-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8WZA6-1", "uniprot_id": "OR1E3_HUMAN", "id": "Q8WZA6-1", "name": "Olfactory receptor 1E3", "aln": "-------------------------------------MMK---KNQT-MISEFLLLGLPIQPEQQNLFYALFLAVYLTTLLGNLLVIVLIRLDSHLHMPMYLCLSNLSFSDLCFSSVTMPKLLQNMQSQNPSIPFADCLAQMYFHLFYGVLESFLLVVMAYHCYVAICFP---------LHYTTIMSPKCCLGLLTLSWLLTTAHATLHTLLMARLSFCAENVIPHFFCDTSTLLKLACSNTQVNGWVMFFMGGLILVIPFLLLIMSCARIVSTI-LRVPSTGGIQKAFSTCGPHLSVVS--LFYGTIIGLYLCP--LTNHNT---VKDTVMAVMYTGVTHMLNPFIYSLRNRDMRGNPGQSLQHKENFFVFKIVIVGILPLLNLVGVVKLIMKYHSKSVA------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZVZ1-1", "uniprot_id": "D3ZVZ1_RAT", "id": "D3ZVZ1-1", "name": "Olfactory receptor", "aln": "-------------------------------------MTQ---DNES-TVSDFNLLGLPIRAEDQGVYSVLFLIMYLTTVLGNLLIILLIRLDPHLHTPMYFFLSHLALTDISFSSVTAPKMLMNMLTHSQSISYAGCVSQVYFYIAFSDLDSFLLTSMAYDRYVAICHP---------LHYNTIMSQNLCVLLLVMSWALSSANALVHTLLLARLSHFRNNTISHYFCELSALLKLSSSDTTINKMVILPLGTVVITLPFVLILVSYGCIGVTI-LKIPSINGIYKTLSTCGSHLCVVS--LYYGAIIGLYFVP--SSNNTN---DQDAIVAVIYTVVTPMLNPFIYSLRNRDMKGALKNILSRR-LCSQ------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LIW9-1", "uniprot_id": "A0ABK0LIW9_RAT", "id": "A0ABK0LIW9-1", "name": "Olfactory receptor", "aln": "-------------------------------------MME---TNQS-TVSEFILLGLPIQPEDQAVYSVLFLAMYMTTVLGNLLIILLIRLDSHLHTPMYFFLSHLAFTDISFSSVTAPKMLMNMLTHSQSISYAGCVSQIYFFLLFGCIDNFLLTSMAYDRYVAICHP---------LHYTTVMSQSLCVLLVMISWVFSSTNGLVHTLLFARLSHFKDNTVHHFFCDLSALLKLSISDTTINELVILTLAVVVITVPFICILISYGHIGATI-LRTPTIQGICKALSTCGSHLCVVF--LYYGAIIGLYFFP--SSNNTN---AKDVIASVLYTVVTPMLNPFIYSLRNRDMKGALKNTLSRR-LCSH------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGS3-1", "uniprot_id": "OR1J1_HUMAN", "id": "Q8NGS3-1", "name": "Olfactory receptor 1J1", "aln": "-------------------------------------MSP---ENQS-SVSEFLLLGLPIRPEQQAVFFALFLGMYLTTVLGNLLIMLLIQLDSHLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQHLAVFYKGCISQTYFFIFFADLDSFLITSMAYDRYVAICHP---------LHYATIMTQSQCVMLVAGSWVIACACALLHTLLLAQLSFCADHIIPHYFCDLGALLKLSCSDTSLNQLAIFTAALTAIMLPFLCILVSYGHIGVTI-LQIPSTKGICKALSTCGSHLSVVT--IYYRTIIGLYFLP--PSSNTN---DKNIIASVIYTAVTPMLNPFIYSLRNKDIKGALRKLLSRSGAVAHACNLNTLGG---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3Z9I7-1", "uniprot_id": "D3Z9I7_RAT", "id": "D3Z9I7-1", "name": "Olfactory receptor", "aln": "-------------------------------------MRL---KNHS-SVSEFLLLGLPIRAEQSGIFFSMFLAMYLTTVLGNLLIILLIRLDSHLHTPMYFFLSHLAFTDISFSSVTVPKMLTKVPNQNIPITYEGCVSQTYFFIFFADLDSFLITSMAYDRYMAICHP---------LNYTTIMNQSRCATLVAISWIIASACALLHTLLLDQLSFCADHTIPHFFCDLGALLKLSCSDTSLNQLVIFTAGLAAIMLPFLCILISYGHIGFTI-LQVPSTKGICKALSTCGSHLSVVA--LYYGSIIGLYFLP--PSNSTI---NNNIVASVMYTVVTPMLNPFIYSLRNKDMKGALRKLLSKKVEFSN------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGS2-1", "uniprot_id": "OR1J2_HUMAN", "id": "Q8NGS2-1", "name": "Olfactory receptor 1J2", "aln": "-------------------------------------MSP---ENQS-SVSEFLLLGLPIRPEQQAVFFTLFLGMYLTTVLGNLLIMLLIQLDSHLHTPMYFFLSHLALTDISFSSVTVPKMLMDMRTKYKSILYEECISQMYFFIFFTDLDSFLITSMAYDRYVAICHP---------LHYTVIMREELCVFLVAVSWILSCASSLSHTLLLTRLSFCAANTIPHVFCDLAALLKLSCSDIFLNELVMFTVGVVVITLPFMCILVSYGYIGATI-LRVPSTKGIHKALSTCGSHLSVVS--LYYGSIFGQYLFP--TVSSSI---DKDVIVALMYTVVTPMLNPFIYSLRNRDMKEALGKLFSRATFFSW------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGS1-1", "uniprot_id": "OR1J4_HUMAN", "id": "Q8NGS1-1", "name": "Olfactory receptor 1J4", "aln": "-------------------------------------MKR---ENQS-SVSEFLLLDLPIWPEQQAVFFTLFLGMYLITVLGNLLIILLIRLDSHLHTPMFFFLSHLALTDISLSSVTVPKMLLSMQTQDQSILYAGCVTQMYFFIFFTDLDNFLLTSMAYDRYVAICHP---------LRYTTIMKEGLCNLLVTVSWILSCTNALSHTLLLAQLSFCADNTIPHFFCDLVALLKLSCSDISLNELVIFTVGQAVITLPLICILISYGHIGVTI-LKAPSTKGIFKALSTCGSHLSVVS--LYYGTIIGLYFLP--SSSASS---DKDVIASVMYTVITPLLNPFIYSLRNRDIKGALERLFNRATVLSQ------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH92-1", "uniprot_id": "OR1S1_HUMAN", "id": "Q8NH92-1", "name": "Olfactory receptor 1S1", "aln": "-------------------MKTFS-----SFLQIGRNMHQ---GNQT-TITEFILLGFFKQDEHQNLLFVLFLGMYLVTVIGNGLIIVAISLDTYLHTPMYLFLANLSFADISSISNSVPKMLVNIQTKSQSISYESCITQMYFSIVFVVIDNLLLGTMAYDHFVAICHP---------LNYTILMRPRFGILLTVISWFLSNIIALTHTLLLIQLLFCNHNTLPHFFCDLAPLLKLSCSDTLINELVLFIVGLSVIIFPFTLSFFSYVCIIRAV-LRVSSTQGKWKAFSTCGSHLTVVL--LFYGTIVGVYFFP--SSTHPED---TDKIGAVLFTVVTPMINPFIYSLRNKDMKGALRKLINRKISSL-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGQ3-1", "uniprot_id": "OR1S2_HUMAN", "id": "Q8NGQ3-1", "name": "Olfactory receptor 1S2", "aln": "-------------------MKTLC-----SFLQISRNMHQ---ENQT-TITEFILLGLSNQAEHQNLLFVLFLSMYVVTVVGNGLIIVAISLDIYLHTPMYLFLAYLSFADISSISNSVPKMLVNIQTNSQSISYESCITQMYFSIVFVVTDNLLLGTMAFDHFVAICHP---------LNYTTFMRARFGTLLTVISWFLSNIIALTHTLLLIQLLFCDHNTLPHFFCDLAPLLKLSCSDTMINELVLFIVGLSVIIFPFVLIFFSYVCIIRAV-LGVSSTQGKWKAFSTCGSHLTIAL--LFYGTTVGVYFFP--SSTHPED---TDKIGAVLFTVVTPMMNPFIYSLRNKDMKGALRKLINRKISSL-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1LV45-1", "uniprot_id": "F1LV45_RAT", "id": "F1LV45-1", "name": "Olfactory receptor", "aln": "-----------------------------------RNMSQ---GNQT-TISEFILLGLSNQAEKQKFIFVIFLSMYLVTVLGNSLIILVIGLDVNLHTPMYLFLANLSFADISSSSTSVPKMLMNIQTKSQYISYEGCFTQMYFSIVFVVIDNFLLGVMAYDRYVAICHP---------LTYTSIMHSTFCLLLTVCPWALSNIVALTHTLLANQLIFCNDNTIQHFFCDLAPLLKLSCSDAMINNIVKFIVGLSVITFPFALILFSYVCIIRDV-LRISSMEGKWKAFSTCGSHLTVVF--LFYGTIIGVYFFP--LSTHPED---TDKIGAVLFTVVTPMLNPFIYSLRNKDMKGAFKKLINKSHFFLLMS----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEU7-1", "uniprot_id": "Q8VEU7_MOUSE", "id": "Q8VEU7-1", "name": "Olfactory receptor", "aln": "-------------------MLPFNDEDEFSLFRYSRTMHQ---GNQT-AISGFILLGLTVGSEQQLLLFTLFLCMYLVTMVGNSLIILAIISDTHLYSPMYFFLANLSFTDICFTTTTVPKILADIQSQNPTISFVGCFTQMYFFMFLVDLDNFLLAAMAYDRYIAICHP---------LHYAALLNPKRCALLVVVPWVISNLVSVLHLSLLSRLPFCDQRVIPHFFCDLEPVLRLACSDTQINNLLILIVGGTVIFVPFVFILVSYALIGTAV-LNVPSVKGKWKTFSTCGSHLSAVS--LFYGSIVGVYFLP--ASSYSAE---RDKVAAIMYTVVTPMMNPFIYSLRNKDMKRALRRLLSQKSLICSW-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A4S6-1", "uniprot_id": "D4A4S6_RAT", "id": "D4A4S6-1", "name": "", "aln": "-------------------------------------MAV---TNLT-YRPQFQLLGLMDGADTHPLLFLLFLSIYLLNALGNLSMVVLVRSDGALCSPMYYFLGHLSLVDVCFTTVTVPRLLVTLLHPGQAMSFQDCFAQMYFFVALGITESYLLAAMSYDRVVAVCRP---------LHYGVVMTPWRCFVLVAASWTVAHLHSLLHTLLISALSYPRSAPVHHFFCDMTVMLSLATSDTSTAETAIFSEGLAVVLTPLILVSLSYARILVAV-LGMQTTGGRHRVFSTCGAHLVVVS--LFFGSVLSVYFRP--SFGYSAR---YDRMASVVYAVVTPTLNPFIYSLRNKEVKGALKRGFRWRAAAQDE-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VFY0-1", "uniprot_id": "Q8VFY0_MOUSE", "id": "Q8VFY0-1", "name": "", "aln": "-------------------------------------MAV---TNLT-YKPQFQLLGLMDGTDPHPLLFLLFLSIYLLNALGNLSMVVLVRSDGALCSPMYYFLGHLSLVDVCFTTVTVPRLLATLLHPGQAISFQACFAQMYFFVALGITESYLLAAMSYDRAVAVCRP---------LHYGAVMTPWRCFLLVAASWAVAHLHSLLHTLLISALTYPPSAPVRHFFCDMTVMLSLATSDTSAAETAIFSEGLTVVLTPLLLVSLSYARILVAV-LGIRTTGGRHRVFSTCGAHLVVVS--LFFGSVLSVYFRP--SSAYSAR---YDRMASVVYAVVTPTLNPFIYSLRNKEVKSALKRGFRWRAAPQDE-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A286YEU6-1", "uniprot_id": "OR1R1_HUMAN", "id": "A0A286YEU6-1", "name": "Olfactory receptor 1R1", "aln": "-------------------------------------MAP---TNLT-SAPVFLLLGLVDGTDAHPLLFLLCLGIYLLNALSNLSMVALVRSDGALRSPMYYFLGHLSLVDVCFTTVTVPRLLAGLLHPGQAISFQACFAEMYFFVALGITESYLLAAMSYDRPTAACRP---------LRYGALVTPWRCASLVRASWAVTHLHSLLHTLLLSALSYPYPTPVRPFFCDMTVMLSLATSDTSAAETAIFSEGLAVVLAPLLLVFLFLR--AHPG-RGARLAGGRRRAFSTCGAHLVAVAVALFFGSVLSVYFPP--SSAYSAR---YDRLASVVYAVITPTLNPFINSLRNKEVKGALKRGLRWRAAPQEA-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGR2-1", "uniprot_id": "OR1L6_HUMAN", "id": "Q8NGR2-1", "name": "Olfactory receptor 1L6", "aln": "MSYFYRLKLMKEAVLVKLPFTSLPLLLQTLSRKSRDMEIK---NYSS-STSGFILLGLSSNPQLQKPLFAIFLIMYLLAAVGNVLIIPAIYSDPRLHTPMYFFLSNLSFMDICFTTVIVPKMLVNFLSETKVISYVGCLAQMYFFMAFGNTDSYLLASMAIDRLVAICNP---------LHYDVVMKPRHCLLMLLGSCSISHLHSLFRVLLMSRLSFCASHIIKHFFCDTQPVLKLSCSDTSSSQMVVMTETLAVIVTPFLCIIFSYLRIMVTV-LRIPSAAGKWKAFSTCGSHLTAVA--LFYGSIIYVYFRP--LSMYSVV---RDRVATVMYTVVTPMLNPFIYSLRNKDMKRGLKK-LQDRIYR--------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TRY4-1", "uniprot_id": "Q7TRY4_MOUSE", "id": "Q7TRY4-1", "name": "Olfactory receptor", "aln": "-------------------------------------MLR---ENQS-HMTEFLLLGLTSNPKQQVWLFASFLAMYLVNVIGNSVIIASIQRDARLHTPMYFFLSNLSLVDICFTTVIVPQMLVNLLTQRKTILFAQCLTQMYFFVAFGITDSFLLAAMAIDRYVAICNP---------LHYNTVMSPRRCRLLVVASWAVSHLHSLTHTILMGRLSFCGPNVIHHFFCDVQPLLTLSCSDTSINELLAFTEGSVVIMSPFIFIVVSYIYITRTV-LRVPSGEGRYKVFSTCGSHLTVVA--LFYGTIISVYIRP--SSTYSVT---KDRVVTVIYTVVTPMLNPFIYSLRNKDMKQALRK-LAKRTE---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LNM5-1", "uniprot_id": "A0ABK0LNM5_RAT", "id": "A0ABK0LNM5-1", "name": "", "aln": "-------------------------------------MAP---VNQS-VVTMFILQNFVDDPWIQDVLFCLFFALFMMAIAGNGLIIMTIYSSANLHTPMYFFLVNLSLMDVICTVTVLPKVLQSLVA-ENAISYGGCLTQMFVFSWVLGSELLLFSAMAYDRYLAICRP---------LHYGTLMNGRACVALATFVWFTGALNSLVLTCLVLPLSFCGPNLITHFFCEIPSVLMLSCSSTFINDIMTVITDMFLTGLNFLLTMTSYVFIIASI-LRIRSAEGKKRAFSTCSAHLVVVT--LYYSTVLYTYVRP--ALGTAGL---LDKAVAVLYTTVTPSLNPLIYTLRNKEFKTSFKKLLFPH-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6B0Y0-1", "uniprot_id": "A0A8I6B0Y0_RAT", "id": "A0A8I6B0Y0-1", "name": "", "aln": "-------------------------------------MAP---INQS-VVTMFFLQNFVDDPWIQNVLFCFFFALFVAAIAGNGLIITVIHSSANLHTPMYFFLVNLSLMDVICTVTVLPKVLQSLVA-ENAISYGGCLTQMFVFSWVLGSELLLFSAMAYDRYLAICRP---------LHYGTLMSGRVCIALATFVWFTGALNSLVLTCLVLPLSFCGPNLITHFFCEIPSVLMLSCSPTFINDIMTVIADMFLTGLNFLLTMTSYGFIIASI-LRIRSAEGKKRAFSTCSAHLVVVT--LYYSTVLYTYVRP--ALGTSGL---LDKVIAVLYTTVTPSLNPLIYTLRNKEFKTSFKKLLFPN-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2K0L2-1", "uniprot_id": "A0A0G2K0L2_RAT", "id": "A0A0G2K0L2-1", "name": "", "aln": "-------------------------------------------MNGT-LVTEFLILGFSEMPHLRVP-LLSFLCLYMAAISGNLLIMVTVSASPALHTPMYFFLVNLAVVDILCTSTILPKLLDIMVG-GRTISYGGCMAQLFFFTWSMGAELLLFSAMAYDRFVAICCP---------LHYSTWMGPRVCAFLAGLVWSISLTNTSVNTSLVLHLPFCSSNVIEHFFCEIPPLLKLSCAPTQLNEVMAFAADVFLAVGNFSVIILSYGFIVTSI-LKIRSTEGKQRAFSTCSAHLFVVT--MYYSTIIYTYIRP--ASSYSLN---KDKVVSIIYTSVAPTLNPLIYTLRNKDVKVALRKLLSSC-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TRT9-1", "uniprot_id": "Q7TRT9_MOUSE", "id": "Q7TRT9-1", "name": "", "aln": "---------------------------------------M---MNGT-LVTEFLILGFSEMPHLRVPLLFSFLCLYMAAISGNLLIMVTISASPALHTPMYFFLVNLAIVDILCTSTILPKLLDSMMT-GRTISYGGCMAQLFFFTWSLGAELLLFSAMAYDRFVAICCP---------LHYSAWMGPRVCAFLAGIVWTISLTNTSVHTGLMLRLPFCSSNVIEHFFCEIPPLLKLSCAPTQLNEAMAFAADVFLAVGNFSVTILSYGFIVASI-LKIRSAEGKRRAFSTCSAHLIVVT--MYYSTVIYTYIRP--SSSYSLN---KDKVVSIIYTSVAPTLNPLIYTLRNKDVKVALRRLLSCC-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGL2-1", "uniprot_id": "Q8VGL2_MOUSE", "id": "Q8VGL2-1", "name": "", "aln": "-------------------------------------------MNGT-LVTEFLILGFSDMPHLRILLFLSFLCLYMAAVSGNLLIMVTISASPTLHTPMYFFLVNLAVVDILCTSTILPKLLDTMVG-GRTISYGGCMAQLFFFTWSLGVELLLFSAMAYDRFVAICCP---------LHYSTWMGPRVCAFLAGIVWAISLTNTSINSSLVLRLPFCSSNVVEHFFCEIPPLLKLSCAPTQLNEAMAFAADVFLAVGNFSVIILSYGFIVASI-LKIRSAEGKQRAFSTCSAHLIVVT--MYYSTVIYTYIRP--SSSYSLN---KDKVVSIIYTSVAPTLNPLIYTLRNKDVKVALRRLFSCC-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TS01-1", "uniprot_id": "Q7TS01_MOUSE", "id": "Q7TS01-1", "name": "", "aln": "---------------------------------------M---MNFS-IVSEFMILGLTQKSELQGILFIVFLFIYLVALLGNMLIVVAIIYNTTLHTPMYILLLALAVVDIICTTSIIPKMLGTMLTSKNSISYGGCMSQLFFFTWSLGAEMVLFTTMAYDRYVAICFP---------LRYSTIMNHYTCVGLLSIVMAIAVTNSWVHTGLILRLTFCGPNIIDHFFCEIPPLLALSCSPVRVNEVMVYVADITLAVGDFTLTCISYGFIIAAI-LRIRTTEGKKKAFSTCSSHLMVVS--LYYSPVIYTYIRP--ASSYTFD---KDKVVAALYTLVTPTLNPIVYSFRNKEMQSGIKKVFAFLKG---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGZ3-1", "uniprot_id": "O13G1_HUMAN", "id": "Q8NGZ3-1", "name": "Olfactory receptor 13G1", "aln": "-------------------------------------------MNHS-VVTEFIILGLTKKPELQGIIFLFFLIVYLVAFLGNMLIIIAKIYNNTLHTPMYVFLLTLAVVDIICTTSIIPKMLGTMLTSENTISYAGCMSQLFLFTWSLGAEMVLFTTMAYDRYVAICFP---------LHYSTIMNHHMCVALLSMVMAIAVTNSWVHTALIMRLTFCGPNTIDHFFCEIPPLLALSCSPVRINEVMVYVADITLAIGDFILTCISYGFIIVAI-LRIRTVEGKRKAFSTCSSHLTVVT--LYYSPVIYTYIRP--ASSYTFE---RDKVVAALYTLVTPTLNPMVYSFQNREMQAGIRKVFAFLKH---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LI97-1", "uniprot_id": "A0ABK0LI97_RAT", "id": "A0ABK0LI97-1", "name": "Olfactory receptor", "aln": "------------------------------------------------MVIEFLFSVFPPLHEGGLLFFILLILVYAFIISGNLVIFVAVQLDLALHTPMYFFISVLSFLEIWYTTTTIPKMLSSLVSEKKTISLGGCLMQMYFFHSLGITEGCVLTAMSIDRYIAICYP---------LRYPTIMTSKLCIQLTAGSCFCGFLLVLPEIAWIATLPFCGSNKIHQIFCDFTPVLRLACTDTSLVV-IVDAIHAVEILASFLVIALSYIRIIMVI-LGMPSAEGRHKAFSTCAAHLAVFL--LFFGSVAVMYLRF--SATYSVF---WDTVIAVTFVILAPFLNPIIYSLRNKEMKDAIGRLFH-RKRDARAQK---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGW6-1", "uniprot_id": "OR6K6_HUMAN", "id": "Q8NGW6-1", "name": "Olfactory receptor 6K6", "aln": "---------MKQYSVGNQHSNYRSLLFPFLCSQMTQLTAS---GNQT-MVTEFLFSMFPHAHRGGLLFFIPLLLIYGFILTGNLIMFIVIQVGMALHTPLYFFISVLSFLEICYTTTTIPKMLSCLISEQKSISVAGCLLQMYFFHSLGITESCVLTAMAIDRYIAICNP---------LRYPTIMIPKLCIQLTVGSCFCGFLLVLPEIAWISTLPFCGSNQIHQIFCDFTPVLSLACTDTFLVV-IVDAIHAAEIVASFLVIALSYIRIIIVI-LGMHSAEGHHKAFSTCAAHLAVFL--LFFGSVAVMYLRF--SATYSVF---WDTAIAVTFVILAPFFNPIIYSLKNKDMKEAIGRLFHYQKRAGWAGK---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6A5L7-1", "uniprot_id": "A0A8I6A5L7_RAT", "id": "A0A8I6A5L7-1", "name": "Olfactory receptor", "aln": "-------------------------------------MRI---NRTT-SVTEFLFSGLPEFEDGRFLFFIPLFFIYVFIVIGNLIVFFAVRMDTRLHNPMYNFISIFSFLEIWYTTATIPKMLSNLISKRRTISLIGCLLQMYFFHSLGNSEGILLTTMAIDRYIAICNP---------LRYPTIMTPRLCAQLSAGSCIFGFLVLLPEIAWISTLPFCGPNQIHQIFCDFEPVLRLACTDTSMIL-VEDVVHAVAIIFSVLVIAFSYIRIITVI-LRIPSGEGRRKAFSTCAAHLGVFL--MFYGSVSLMYLRF--SATFPPV---LDTAIALMFAVLAPFFNPIIYSLRNKDMKTAIKKLLSSPTMLPTSAS---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGY3-1", "uniprot_id": "OR6K3_HUMAN", "id": "Q8NGY3-1", "name": "Olfactory receptor 6K3", "aln": "--------------------MCWTMPSPFTG-SSTRNMES---GNQS-TVTEFIFTGFPQLQDGSLLYFFPLLFIYTFIIIDNLLIFSAVRLDTHLHNPMYNFISIFSFLEIWYTTATIPKMLSNLISEKKAISMTGCILQMYFFHSLENSEGILLTTMAIDRYVAICNP---------LRYQMIMTPRLCAQLSAGSCLFGFLILLPEIVMISTLPFCGPNQIHQIFCDLVPVLSLACTDTSMIL-IEDVIHAVTIIITFLIIALSYVRIVTVI-LRIPSSEGRQKAFSTCAGHLMVFP--IFFGSVSLMYLRF--SDTYPPV---LDTAIALMFTVLAPFFNPIIYSLRNKDMNNAIKKLFCLQKVLNKPGG---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AP46-1", "uniprot_id": "A0A8I6AP46_RAT", "id": "A0A8I6AP46-1", "name": "Olfactory receptor", "aln": "-------------------------------------MDH---VNCT-WNWIFILAGFNTSGTLQQLAVFGTLCIYLLTLAGNLFIIVLVQADSGLSTPMYFFISVLSFLEIWYVSTTVPTLLHTLLHGHSPIPSAACFIQLYVFHSLGMTECYLLGVMALDRYLAICRP---------LHYHSLMSRQVQRELVLITWVAGFSAALVPAGLTATLPYC-LKEVAHYFCDLGPVMQLACVDTSWHARVYIAVIGMINTCNLVFILGLYGGIVKAV-LRLPSAASRAKAFSTCSSHITVVT--LFFGSAFIVYVGP--PEIRAEG---RGKLIALVYTLFTPFFNPIIYTLRNKEVKAAFKRVTQRIKGVLG------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZIK6-1", "uniprot_id": "D3ZIK6_RAT", "id": "D3ZIK6-1", "name": "Olfactory receptor", "aln": "-------------------------------------MDH---VNYT-WTRTFILAGFTTSGTLQQLSVFGTLCIYLLTIAGNIFIIVLVQADSGLSTPMYFFISVLSFLEIWYVSTSVATLLHTLLHGHSPIPSAACFIQLYVFHSLGMTECYLLSVMALDRYLAICRP---------LHYHALMSRQVKIQLVLITWVAGFSVALVPAGLTASLPYC-LKEVAHYLCDLEPVIRLACVDTSWHARVYITVIGIIITCNLVSILGLYGGIAKAV-LRLPSAASRAKAFSTCSSHITVVT--LFYGSAFIVYVGP--PEIRAEG---RDKLIALVYTLFTPFFNPIIYTLRNKEVKAAFKRVTQRIQGVLS------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q8M2-1", "uniprot_id": "E9Q8M2_MOUSE", "id": "E9Q8M2-1", "name": "Olfactory receptor", "aln": "-------------------------------------MDH---VNYT-WTRTFILAGFTTSGTLQHLAVFGTLCIYLLTLAGNLFIIVLIQADSGLSTPMYFFISVLSFLELWYVSTTVPTLLHTLLHGPSPIPSSACFVQLYVFHSLGMTECYLLGVMALDRYLAICRP---------LHYHALMSRQVQKQLVGVTWLAGFSAALVPAGLTASLPYC-LKEVAHYFCDLAPVMQLACVDTSWHARLYIAVIGMINTCNLTFILGLYGGIVRAV-LKLPSAASRAKAFSTCSSHITVVT--LFFGSAFIVYVGP--PEIRAEG---RDKLIALVYTLLTPFFNPIIYTLRNKEVKEAFKRVTQRINAVLK------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TRV9-1", "uniprot_id": "Q7TRV9_MOUSE", "id": "Q7TRV9-1", "name": "Olfactory receptor", "aln": "-------------------------------------MDH---VNYT-WTRTFILAGFTTSGALRPLAFLGTLCIYLLTLAGNLFIIVLVQADSGLSTPMYFFISVLSFLELWYVSTTVPTLLHTLLHGHSPIPSSACFVQLYVFHSLGMTECYLLGVMALDRYLAICRP---------LHYHALMSRQVQLWLAGATWVAGFSAALVPACLTASLPYC-LKEIAHYFCDLAPLMRLACVSTRWHARVHGAVIGVATGCNFVLILGLYGGILTAV-LKLPSAASRAKAFSTCSSHMTVVA--LFYASAFTVYVGS--PQSRPEG---TDKLIALVYALLTPFLNPIIYSLRNKEVKEAVKRVSEKIRTLLRDT----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9I8Z1-1", "uniprot_id": "Q9I8Z1_DANRE", "id": "Q9I8Z1-1", "name": "", "aln": "--------------------------------------MSLYENNSIVRPEYFFIIGLSGIPN-SSYYYIFLFIIYCITVIGNSLVLLIIALDRSLHSAKYLCVFNLALADFGETNAVIPNMLKTFLFDSQYISYNACLANMFFVNYFINVQSATLVVLAFDRVIAICLP---------LRYHSIVNNIVMLIVFFGIWTLNTLVVALSVSLMTRLSICKSNVVESYYCDYGPVLRLACNDSTVNKIITNVIAVMSLVAPVILIVLSYLGIFFAL-SKITTWEGRLKALKTCVSHLLIVG--LFFLPVICIFIASS-TSTLTPN---VRIISTSLSFTLPPMLNPIIYVLNTAEIKDTIRKKFKKRIFT--------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . : .* :. * : : :: : . * : *. : . : :: . * * : : : : : :: :: :.:.** *: : : : . ..*:: :.. :. . ", "identical_positions": 11, "similar_positions": 48, "identity": "2.66%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010308-12", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TQQ0-1", "uniprot_id": "OR4E2_MOUSE", "id": "Q7TQQ0-1", "name": "Olfactory receptor 4E2", "aln": "----------------------------------------MGALNQT-RVTEFIFLGLTDNWVLEILFFVPFTVTYMLTLLGNFLIVVTIVFTPRLHNPMYFFLSNLSFIDICHSSVTVPKMLEGLLLERKTISFDNCIAQLFFLHLFACSEIFLLTIMAYDRYVAICIP---------LHYSNVMNMKVCVQLVFALWLGGTIHSLVQTFLTIRLPYCGPNIIDSYFCDVPPVIKLACTDTYLTGILIVSNSGTISLVCFLALVTS--YTVILFSLRKQSAEGRRKALSTCSAHFMVVA--LFFGPCIFLYTRP----DSSFSIDKVVSVFYTVVTPLLNPLIYTLRNEEVKTAMKHLRQRRICS--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ADC0-1", "uniprot_id": "D4ADC0_RAT", "id": "D4ADC0-1", "name": "Olfactory receptor", "aln": "----------------------------------------MGALNQT-RVTEFVFLGLTDNWVLEILFFIPFTVTYVLTLLGNVLIVVTIVFTPRLHNPMYFFLSNLSFIDICHSSVTVPKMLEGLLLVRKTISFDNCIAQLFFLHLFACAEIFLLTIMAYDRYVAICIP---------LHYPNVMNMKVCVQLVFALWLGGTVHSLVQTFLTIRLPYCGPNTIDSYFCDVPPVIKLACTDTYLTGILIVSNSGTISLVCFLALVTS--YTVILFSLRKQSAEGRRKALSTCSAHFMVVA--LFFGPCIFIYTWP----DTSFSIDKVVSVFYTVVTPLLNPLIYTLRNEEVKTSMKHLRQRRICS--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGC2-1", "uniprot_id": "OR4E2_HUMAN", "id": "Q8NGC2-1", "name": "Olfactory receptor 4E2", "aln": "----------------------------------------MDSLNQT-RVTEFVFLGLTDNRVLEMLFFMAFSAIYMLTLSGNILIIIATVFTPSLHTPMYFFLSNLSFIDICHSSVTVPKMLEGLLLERKTISFDNCITQLFFLHLFACAEIFLLIIVAYDRYVAICTP---------LHYPNVMNMRVCIQLVFALWLGGTVHSLGQTFLTIRLPYCGPNIIDSYFCDVPLVIKLACTDTYLTGILIVTNSGTISLSCFLAVVTS--YMVILVSLRKHSAEGRQKALSTCSAHFMVVA--LFFGPCIFIYTRP----DTSFSIDKVVSVFYTVVTPLLNPFIYTLRNEEVKSAMKQLRQRQVFFTKSYT---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R0K4-1", "uniprot_id": "Q9R0K4_MOUSE", "id": "Q9R0K4-1", "name": "Olfactory receptor", "aln": "-------------------------------------MEKAVLINETSVMS-FRLTGLSTNPLVQMAVFFIFLIFYVLTLVGNILIVITIIYDRRLHTPMYFFLSNLSFIDVCHSTVTVPKMLSDTFSEEKLISFDACVVQMFFLHLFACTEIFLLTVMAYDRYVAICKP---------LQYMTIMNWKVCMMLAAALWTGGTIHSISLTSLTIKLPYCGPDEIDNFFCDVPQVIKLACTDTHIIEILIVSNSGLISVVCFVVLVVS--YAVILVSLRQQISDGKRKALSTCAAHLTVVT--LFLGHCIFIYSRP----STSLPEDKVVSVFFTAVTPLLNPIIYTLRNEDMKSALNKLIKRREK---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C645-1", "uniprot_id": "OR4E1_HUMAN", "id": "P0C645-1", "name": "Olfactory receptor 4E1", "aln": "-------------------------------------MEEAILLNQTSLVTYFRLRGLSVNHKARIAMFSMFLIFYVLTLIGNVLIVITIIYDHRLHTPMYFFLSNLSFIDVCHSTVTVPKMLRDVWSEEKLISFDACVTQMFFLHLFACTEIFLLTVMAYDRYVAICKP---------LQYMIVMNWKVCVLLAVALWTGGTIHSIALTSLTIKLPYCGPDEIDNFFCDVPQVIKLACIDTHVIEILIVSNSGLISVVCFVVLVVS--YAVILVSLRQQISKGKRKALSTCAAHLTVVT--LFLGHCIFIYSRP----STSLPEDKVVSVFFTAVTPLLNPIIYTLRNEEMKSALNKLVGRKERKEEK-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2I3BQG5-1", "uniprot_id": "A0A2I3BQG5_MOUSE", "id": "A0A2I3BQG5-1", "name": "Olfactory receptor", "aln": "----------------------------MSAPTSVYQGSNSVLLNQT-LVTEFLLLGVTDIQELNPILFVTVLAMYFVNVAGNGAILLIVISDPRLHSPMYFFLGNLACLDICFSTVTVPKILDNFFSTSKAISFLGCITQLYFFHLLGSTEALLLAVMAFDRFVAICRP---------LHYPSIMNGQVCIQVAISIWAIPFVHALVHSILTSQLNFCGSNQIHHFFCDVKPLLELACGNTELNRWLLNTFTGTFAIGLFFLTFLSYFYIITYLFLKTRSCSMLHKALSTCASHFMVVM--IFYAPVLFIYINP--DSGSSLEKDRIIAVMYTVVTPALNPLIYTLRNKEVRGALNRKLRILL----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2I3BRX0-1", "uniprot_id": "A0A2I3BRX0_MOUSE", "id": "A0A2I3BRX0-1", "name": "Olfactory receptor", "aln": "----------------------------MSAPTSVSQEGNSVLLNHT-LVTEFLLLGVTDIQELNPILFVTVLAMYFVNVAGNGAILMIVISDPRLHLPMYFFLGNLACLDICFSTVTVPKMLENFFSTSKAISFLGCITQLHFFHFLGSTEALLLTVMAFDRFVAICRP---------LHYPAIMNSQVCIQVAISIWAIPFLHALVHSILTSQLNFCGSNHIHHFFCDVKPLLELACGNTELNRWLLNTLTGTVAIGLFFLTFLSYFYIVTYLFLKTRSCSMLHKALSTCASHFMVVM--IFYAPVLFIYINP--DSGSSLEKDRIIAVMYTVVTPALNPLIYTLRNKEVRGALNRKIRILL----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58182-1", "uniprot_id": "O12D2_HUMAN", "id": "P58182-1", "name": "Olfactory receptor 12D2", "aln": "------------------------------------------MLNTT-SVTEFLLLGVTDIQELQPFLFVVFLTIYFISVTGNGAVLMIVISDPRLHSLMYFFLGNLSYLDICYSTVTLPKMLQNFLSTHKAISFLGCISQLHFFHSLGSTESMLFAVMAFDLSVAICKP---------LRYTVIMNPQLCTQMAITIWVIGFFHALLHSVMTSRLNFCGSNRIHHFLCDIKPLLKLACGNTELNQWLLSTVTGTIAMGPFFLTLLSYFYIITYLFFKTRSCSMLCKALSTCASHFMVVI--LFYAPVLFTYIHP--ALESFMDQDRIVAIMYTVVTPVLNPLIYTLRNKEVKGALGRVIRRL-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VG96-1", "uniprot_id": "Q8VG96_MOUSE", "id": "Q8VG96-1", "name": "Olfactory receptor", "aln": "------------------------------------------MENST-SVDEFLLLGLTSVQKLQPIIFVMFLTIYLLNLVGNGVILMIVTLERRLHSPMYFFLGNLSCLDICYSSVTLPKVLINLLSRRRAISFLGCITQLYFFHFLGSTEAILLAVMAFDRFVAICSP---------LRYTAIMNPQLCILLAATAWFTSFFYALLHSVMTAHLNFCHSHKLSHFFCDVKPLLEVACGNTVLNQWLLSVVTGSISMGAFLLILLSYFYIIAFLLFKNRSCRMLKKALSTCTSHFMVVC--LFYGPVGFTYIRPATASASSMSEDRVVAIIYSAVTPVLNPLIYTLRNKEVMLALKKNFGKKLFKGN------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGF7-1", "uniprot_id": "O12D3_HUMAN", "id": "Q9UGF7-1", "name": "Olfactory receptor 12D3", "aln": "------------------------------------------MENVT-TMNEFLLLGLTGVQELQPFFFGIFLIIYLINLIGNGSILVMVVLEPQLHSPMYFFLGNLSCLDISYSSVTLPKLLVNLVCSRRAISFLGCITQLHFFHFLGSTEAILLAIMAFDRFVAICNP---------LRYTVIMNPQVCILLAAAAWLISFFYALMHSVMTAHLSFCGSQKLNHFFYDVKPLLELACSDTLLNQWLLSIVTGSISMGAFFLTLLSCFYVIGFLLFKNRSCRILHKALSTCASHFMVVC--LFYGPVGFTYIRP--ASATSMIQDRIMAIMYSAVTPVLNPLIYTLRNKEVMMALKKIFGRKLFKDWQQHH--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VGG9-1", "uniprot_id": "Q8VGG9_MOUSE", "id": "Q8VGG9-1", "name": "Olfactory receptor", "aln": "-------------------------------------MDG---DNQT-IVTEFILLGLTRQSEKEEVVFGLFLWMYLVTISGNLLIILAISCDPHLHTPMYFFLANLSSVDISAPSVIVPKALVNHMLGSKSISYTGCMTQIYFFITFSNMDGFLLSVMAYDRYVAICHP---------LHYTMMMRPRLCVLLVAISWAITNLHALLHTLLMVRLTFCSHNAVHHFFCDPYPILKLSCSDTFINDLMVFTIGGLVFMTPFTCIIVSYAYIFSKV-LKLKSAHGIRKALSTCGSHLTVVS--LFYGAILGIYMHPSSTYT--VQ-DTVATVIFTVVTPMVNPFIYSLRNRDIKGALRKIILRS-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGH1-1", "uniprot_id": "Q8VGH1_MOUSE", "id": "Q8VGH1-1", "name": "Olfactory receptor", "aln": "-------------------------------------MDG---DNET-MVAEFLLLGLSGKSEQEEVVFGMFLGMYLVTISGNLLIILAISCDPHLHTPMYFFLANLSSVDICFSSVTVPKALVNHVLGSKSISYTECMIQIYFFITFINMDGFLLSVMAYDRYVAICHP---------LHYTMMMRSRLCVLLVAISWVITNLHALLHTLLMVRLTFCSHNAVHHFFCDPYPILKLSCSDTFINDLMVFTVGGVIFLTPFSCIVVSYVYIFSKV-LKIPSARGIRKALSTCGSHLTVVS--LFYGAILGVYMRPSSSYS--LQ-DTVATVIFTVVTPLVNPFIYSLRNQDMKGALRKIMLRS-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NHA8-1", "uniprot_id": "OR1FC_HUMAN", "id": "Q8NHA8-1", "name": "Putative olfactory receptor 1F12P", "aln": "-------------------------------------MEG---KNQT-NISEFLLLGFSSWQQQQVLLFALFLCLYLTGLFGNLLILLAIGSDHCLHTPMYFFLANLSLVDLCLPSATVPKMLLNIQTQTQTISYPGCLAQMYFCMMFANMDNFLLTVMAYDRYVAICHP---------LHYSTIMALRLCASLVAAPWVIAILNPLLHTLMMAHLHFCSDNVIHHFFCDINSLLPLSCSDTSLNQLSVLATVGLIFVVPSVCILVSYILIVSAV-MKVPSAQGKLKAFSTCGSHLALVI--LFYGAITGVYMSPLSNHS--TEKDSAASVIFMVVAPVLNPFIYSLRNNELKGTLKKTLSRPGAVAHACNPSTLGGRGGWIMRSGDRDHPG------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH92-1", "uniprot_id": "OR1S1_HUMAN", "id": "Q8NH92-1", "name": "Olfactory receptor 1S1", "aln": "-------------------MKTFS-----SFLQIGRNMHQ---GNQT-TITEFILLGFFKQDEHQNLLFVLFLGMYLVTVIGNGLIIVAISLDTYLHTPMYLFLANLSFADISSISNSVPKMLVNIQTKSQSISYESCITQMYFSIVFVVIDNLLLGTMAYDHFVAICHP---------LNYTILMRPRFGILLTVISWFLSNIIALTHTLLLIQLLFCNHNTLPHFFCDLAPLLKLSCSDTLINELVLFIVGLSVIIFPFTLSFFSYVCIIRAV-LRVSSTQGKWKAFSTCGSHLTVVL--LFYGTIVGVYFFPSSTHP--EDTDKIGAVLFTVVTPMINPFIYSLRNKDMKGALRKLINRKISSL-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGQ3-1", "uniprot_id": "OR1S2_HUMAN", "id": "Q8NGQ3-1", "name": "Olfactory receptor 1S2", "aln": "-------------------MKTLC-----SFLQISRNMHQ---ENQT-TITEFILLGLSNQAEHQNLLFVLFLSMYVVTVVGNGLIIVAISLDIYLHTPMYLFLAYLSFADISSISNSVPKMLVNIQTNSQSISYESCITQMYFSIVFVVTDNLLLGTMAFDHFVAICHP---------LNYTTFMRARFGTLLTVISWFLSNIIALTHTLLLIQLLFCDHNTLPHFFCDLAPLLKLSCSDTMINELVLFIVGLSVIIFPFVLIFFSYVCIIRAV-LGVSSTQGKWKAFSTCGSHLTIAL--LFYGTTVGVYFFPSSTHP--EDTDKIGAVLFTVVTPMMNPFIYSLRNKDMKGALRKLINRKISSL-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1LV45-1", "uniprot_id": "F1LV45_RAT", "id": "F1LV45-1", "name": "Olfactory receptor", "aln": "-----------------------------------RNMSQ---GNQT-TISEFILLGLSNQAEKQKFIFVIFLSMYLVTVLGNSLIILVIGLDVNLHTPMYLFLANLSFADISSSSTSVPKMLMNIQTKSQYISYEGCFTQMYFSIVFVVIDNFLLGVMAYDRYVAICHP---------LTYTSIMHSTFCLLLTVCPWALSNIVALTHTLLANQLIFCNDNTIQHFFCDLAPLLKLSCSDAMINNIVKFIVGLSVITFPFALILFSYVCIIRDV-LRISSMEGKWKAFSTCGSHLTVVF--LFYGTIIGVYFFPLSTHP--EDTDKIGAVLFTVVTPMLNPFIYSLRNKDMKGAFKKLINKSHFFLLMS----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEU7-1", "uniprot_id": "Q8VEU7_MOUSE", "id": "Q8VEU7-1", "name": "Olfactory receptor", "aln": "-------------------MLPFNDEDEFSLFRYSRTMHQ---GNQT-AISGFILLGLTVGSEQQLLLFTLFLCMYLVTMVGNSLIILAIISDTHLYSPMYFFLANLSFTDICFTTTTVPKILADIQSQNPTISFVGCFTQMYFFMFLVDLDNFLLAAMAYDRYIAICHP---------LHYAALLNPKRCALLVVVPWVISNLVSVLHLSLLSRLPFCDQRVIPHFFCDLEPVLRLACSDTQINNLLILIVGGTVIFVPFVFILVSYALIGTAV-LNVPSVKGKWKTFSTCGSHLSAVS--LFYGSIVGVYFLPASSYS--AERDKVAAIMYTVVTPMMNPFIYSLRNKDMKRALRRLLSQKSLICSW-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGA1-1", "uniprot_id": "OR1M1_HUMAN", "id": "Q8NGA1-1", "name": "Olfactory receptor 1M1", "aln": "-------------------------------------MEP---RNQT-SASQFILLGLSEKPEQETLLFSLFFCMYLVMVVGNLLIILAISIDSHLHTPMYFFLANLSLVDFCLATNTIPKMLVSLQTGSKAISYPCCLIQMYFFHFFGIVDSVIIAMMAYDRFVAICHP---------LHYAKIMSLRLCRLLVGALWAFSCFISLTHILLMARLVFCGSHEVPHYFCDLTPILRLSCTDTSVNRIFILIVAGMVIATPFVCILASYARILVAI-MKVPSAGGRKKAFSTCSSHLSVVA--LFYGTTIGVYLCPSSVLT-TVKEK-ASAVMYTAVTPMLNPFIYSLRNRDLKGALRKLVNRKITSSS------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VFM9-1", "uniprot_id": "OR1M1_MOUSE", "id": "Q8VFM9-1", "name": "Olfactory receptor 1M1", "aln": "-------------------------------------MEP---QNHT-SASEFILLGLSEKPDHDPVLFSLFLCMYMITVVGNLLIILAISFDSHLHTPMYFFLANLSLVDFCLATNTVPKMLVNIQTRNKSISYPCCLTQMYFFHFFGIMDSVLIAVMAYDRFVAICHP---------LHYSTIMSPRLCGLLVGVPWVYSCFISLTHILLMARLVFCGKNELPHYFCDLTPLLRLSCTDTTVNKIFVLIVAGMVIATPFVCILASYARIIVAI-MKVPSAGGRKKAFSTCSSHLSVVA--LFYGTTIGVYLCPSSVRT-AVKEK-ASAVMYTAVTPMLNPFIYSLRNRDLKGALKKIINRKISTSS------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NH06-1", "uniprot_id": "OR1P1_HUMAN", "id": "Q8NH06-1", "name": "Olfactory receptor 1P1", "aln": "-----------------------MGLTQDFFPPTSELLEG---GNQT-STFEFLLWGLSDQPQQQHIFFLLFLWMYVVTVAGNLLIVLAIGTDTHLHTPMYFFLASLSCADIFSTSTTVPKALVNIQTQSRSISYAGCLAQLYFFLTFGDMDIFLPATMAYDRYVAICHL---------LHYMMIMSLHRCAFLVTACWTLTSLLAMTRTFLIFRLSLCSK-ILPGFFCDLGPLMKVSCSDAQVNELVLLFLGGAVILIPFMLILVSYIRIVSAI-LRAPSAQGRRKAFSTCDSHLVVVA--LFFGTVIRAYLCPSSSSSNSVKEDTAAAVMYTVVTPLLNPFIYSMRNKDMKAAVVRLLKGRVSFSQGQ----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VGK1-1", "uniprot_id": "Q8VGK1_MOUSE", "id": "Q8VGK1-1", "name": "Olfactory receptor", "aln": "-------------------------------------ME-----NES-SVSEFFLQGISGFSEQQQLLYGLFLCMYLVTLTGNVLIILAIGSDPHLHTPMYFFLANLSFADMGLISSTVTKMLFNVQTRCHTISYTGCLTQMYFFLMFGDLDSFLLAVMAYDRYVAICHP---------LHYSTIMSARVCALMLALCWVLTNIVALTHTLLMARLSFCVVGEIAHFFCDITPVLKLSCSDTHVNELMVFALGGTVLMVPFVCIVISYIHIVFAI-LKVRTPGGGTKAFSTCSSHLCVVC--VFYGTLFSAYLCPPSVVS--TEKDVAAAAMYTVVTPMLNPFIYSLRNKDMKGALKRLLCHRKFLS-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGK0-1", "uniprot_id": "Q8VGK0_MOUSE", "id": "Q8VGK0-1", "name": "Olfactory receptor", "aln": "-------------------------------------ME-----NQS-SVSEFFLRGISGFPEQQQLLYGLFLCMYLVTLTGNVLIILAISCDPHLHTPMYFFLANLSFADMGLISSAVTKMLFNVQTQRHTISYTGCLTQMYLFMMFGDLDSFFLAVMAYDRYVAICHP---------LHYSTIMSARVCALMLALCWVLTNIVALTHTLLMTRLSFCVVGEIAHFFCDITSVMKLSCSDTHVNELVLSGFGGTVLMVPFVSIVISYVRIVFAV-LRVQTSGGSSKAFSTCSSHLCVVC--VFYGTLFSVYLFPSSGET--TEKDVVAAAMYTVVTPMLNPFIYSLRNKDMKGALKRLLCHRRKFSP------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGS0-1", "uniprot_id": "OR1N1_HUMAN", "id": "Q8NGS0-1", "name": "Olfactory receptor 1N1", "aln": "-------------------------------------ME-----NQS-SISEFFLRGISAPPEQQQSLFGIFLCMYLVTLTGNLLIILAIGSDLHLHTPMYFFLANLSFVDMGLTSSTVTKMLVNIQTRHHTISYTGCLTQMYFFLMFGDLDSFFLAAMAYDRYVAICHP---------LCYSTVMRPQVCALMLALCWVLTNIVALTHTFLMARLSFCVTGEIAHFFCDITPVLKLSCSDTHINEMMVFVLGGTVLIVPFLCIVTSYIHIVPAI-LRVRTRGGVGKAFSTCSSHLCVVC--VFYGTLFSAYLCPPSIAS--EEKDIAAAAMYTIVTPMLNPFIYSLRNKDMKGALKRLFSHRSIVSS------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VGJ8-1", "uniprot_id": "Q8VGJ8_MOUSE", "id": "Q8VGJ8-1", "name": "Olfactory receptor", "aln": "-------------------------------------MGKISRVNQS-VASDFLLLGLSEQPGEQPLLFGIFLGMYLVTMVGNLLIIFVISSDAHLHTPMYFFLANLSLTDACFTSASVPKMLANIYTQSQTISYSGCLTQLYFLLMFGGLDNCLLAVMAYDRYVAICQP---------LHYSTAMSPQLCALMLCTCWVLTNCPALMHTLLLTRVAFCAHTAIPHFYCDPSALLKLACSDTHINELMIITMGLVFLAVPLMLIVFSYVCISWAV-LGIPSSGGRWKAFSTCGSHLTVVL--LFYGSLMGVYLLPPSTHS--TERESRAAVLYMIVIPMLNPFIYSLRNRDMKEAMGKLFGGGKTVFLL-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGR9-1", "uniprot_id": "OR1N2_HUMAN", "id": "Q8NGR9-1", "name": "Olfactory receptor 1N2", "aln": "-------------------------------------MGKPGRVNQT-TVSDFLLLGLSEWPEEQPLLFGIFLGMYLVTMVGNLLIILAISSDPHLHTPMYFFLANLSLTDACFTSASIPKMLANIHTQSQIISYSGCLAQLYFLLMFGGLDNCLLAVMAYDRYVAICQP---------LHYSTSMSPQLCALMLGVCWVLTNCPALMHTLLLTRVAFCAQKAIPHFYCDPSALLKLACSDTHVNELMIITMGLLFLTVPLLLIVFSYVRIFWAV-FVISSPGGRWKAFSTCGSHLTVVL--LFYGSLMGVYLLPPSTYS--TERESRAAVLYMVIIPTLNPFIYSLRNRDMKEALGKLFVSGKTFFL------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TQU7-1", "uniprot_id": "Q7TQU7_MOUSE", "id": "Q7TQU7-1", "name": "", "aln": "-------------------------------------MAP---ENQT-TVLEFHLMGLSEDPDLQTILFGLFLSMYLVTVFGNLLIILAIISDSHLHTPMYFFLCNLSLVDIFFCSTTVPKMLVNIQTQSRAISFTGCLVQMYAFHLFGTIDSFLLAVMAIDRLVAIAYP---------LRYSVLMSPHVCALLVGGTWVITNLQSLVHTCLMAQLTFCARSEIPHFFCDLMPLLKLSCSDTHINELVIFAFGIVMGLSPLSCILVSYICIFRAV-FRIPSAQGKWKAFSTCGSHLTVVS--LFYGTIFTGYLLPASPSS--SQKDKAAALMFGVVIPTLNPFIYSLRNKDMKAALRKLGSKAVS----------------------------------FQS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60431-1", "uniprot_id": "OR1I1_HUMAN", "id": "O60431-1", "name": "Olfactory receptor 1I1", "aln": "-------------------------------------MEP---EKQT-EISEFFLQGLSEKPEHQTLLFTMFLSTYLVTIIGNALIILAIITDSHLHTPMYFFLFNLSLVDTLLSSTTVPKMLANIQAQSRAIPFVGCLTQMYAFHLFGTMDSFLLAVMAIDRFVAIVHP---------QRYLVLMCSPVCGLLLGASWMITNLQSLIHTCLMAQLTFCAGSEISHFFCDLMPLLKLSGSDTHTNELVIFAFGIVVGTSPFSCILLSYIRIFWTV-FKIPSTRGKWKAFSTCGLHLTVVS--LSYGTIFAVYLQPTSPSS--SQKDKAAALMCGVFIPMLNPFIYSIRNKDMKAALGKLIGKVAVPCPRPEQLLDVYHVPGSLLAARDTEMHPIPYPGGVQSLAGNRDME", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P30953-1", "uniprot_id": "OR1E1_HUMAN", "id": "P30953-1", "name": "Olfactory receptor 1E1", "aln": "-------------------------------------MMG---QNQT-SISDFLLLGLPIQPEQQNLCYALFLAMYLTTLLGNLLIIVLIRLDSHLHTPMYLFLSNLSFSDLCFSSVTIPKLLQNMQNQDPSIPYADCLTQMYFFLLFGDLESFLLVAMAYDRYVAICFP---------LHYTAIMSPMLCLALVALSWVLTTFHAMLHTLLMARLCFCADNVIPHFFCDMSALLKLAFSDTRVNEWVIFIMGGLILVIPFLLILGSYARIVSSI-LKVPSSKGICKAFSTCGSHLSVVS--LFYGTVIGLYLCSSANSS--TLKDTVMAMMYTVVTPMLNPFIYSLRNRDMKGALSRVIHQKKTFFSL-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47887-1", "uniprot_id": "OR1E2_HUMAN", "id": "P47887-1", "name": "Olfactory receptor 1E2", "aln": "-------------------------------------MMG---QNQT-SISDFLLLGLPIQPEQQNLCYALFLAMYLTTLLGNLLIIVLIRLDSHLHTPVYLFLSNLSFSDLCFSSVTMPKLLQNMQNQDPSIPYADCLTQMYFFLYFSDLESFLLVAMAYDRYVAICFPMHYTAICFLLHYTAIMSPMLCLSVVALSWVLTTFHAMLHTLLMARLCFCADNVIPHFFCDMSALLKLACSDTRVNEWVIFIMGGLILVIPFLLILGSYARIVSSI-LKVPSSKGICKAFSTCGSHLSVVS--LFYGTVIGLYLCPSANSS--TLKDTVMAMMYTVVTPMLTPFIYSLRNRDMKGALERVICKRKNPFLL-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8WZA6-1", "uniprot_id": "OR1E3_HUMAN", "id": "Q8WZA6-1", "name": "Olfactory receptor 1E3", "aln": "-------------------------------------MMK---KNQT-MISEFLLLGLPIQPEQQNLFYALFLAVYLTTLLGNLLVIVLIRLDSHLHMPMYLCLSNLSFSDLCFSSVTMPKLLQNMQSQNPSIPFADCLAQMYFHLFYGVLESFLLVVMAYHCYVAICFP---------LHYTTIMSPKCCLGLLTLSWLLTTAHATLHTLLMARLSFCAENVIPHFFCDTSTLLKLACSNTQVNGWVMFFMGGLILVIPFLLLIMSCARIVSTI-LRVPSTGGIQKAFSTCGPHLSVVS--LFYGTIIGLYLCPLTNHN--TVKDTVMAVMYTGVTHMLNPFIYSLRNRDMRGNPGQSLQHKENFFVFKIVIVGILPLLNLVGVVKLIMKYHSKSVA------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZVZ1-1", "uniprot_id": "D3ZVZ1_RAT", "id": "D3ZVZ1-1", "name": "Olfactory receptor", "aln": "-------------------------------------MTQ---DNES-TVSDFNLLGLPIRAEDQGVYSVLFLIMYLTTVLGNLLIILLIRLDPHLHTPMYFFLSHLALTDISFSSVTAPKMLMNMLTHSQSISYAGCVSQVYFYIAFSDLDSFLLTSMAYDRYVAICHP---------LHYNTIMSQNLCVLLLVMSWALSSANALVHTLLLARLSHFRNNTISHYFCELSALLKLSSSDTTINKMVILPLGTVVITLPFVLILVSYGCIGVTI-LKIPSINGIYKTLSTCGSHLCVVS--LYYGAIIGLYFVPSSNNT--NDQDAIVAVIYTVVTPMLNPFIYSLRNRDMKGALKNILSRR-LCSQ------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LIW9-1", "uniprot_id": "A0ABK0LIW9_RAT", "id": "A0ABK0LIW9-1", "name": "Olfactory receptor", "aln": "-------------------------------------MME---TNQS-TVSEFILLGLPIQPEDQAVYSVLFLAMYMTTVLGNLLIILLIRLDSHLHTPMYFFLSHLAFTDISFSSVTAPKMLMNMLTHSQSISYAGCVSQIYFFLLFGCIDNFLLTSMAYDRYVAICHP---------LHYTTVMSQSLCVLLVMISWVFSSTNGLVHTLLFARLSHFKDNTVHHFFCDLSALLKLSISDTTINELVILTLAVVVITVPFICILISYGHIGATI-LRTPTIQGICKALSTCGSHLCVVF--LYYGAIIGLYFFPSSNNT--NAKDVIASVLYTVVTPMLNPFIYSLRNRDMKGALKNTLSRR-LCSH------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGS3-1", "uniprot_id": "OR1J1_HUMAN", "id": "Q8NGS3-1", "name": "Olfactory receptor 1J1", "aln": "-------------------------------------MSP---ENQS-SVSEFLLLGLPIRPEQQAVFFALFLGMYLTTVLGNLLIMLLIQLDSHLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQHLAVFYKGCISQTYFFIFFADLDSFLITSMAYDRYVAICHP---------LHYATIMTQSQCVMLVAGSWVIACACALLHTLLLAQLSFCADHIIPHYFCDLGALLKLSCSDTSLNQLAIFTAALTAIMLPFLCILVSYGHIGVTI-LQIPSTKGICKALSTCGSHLSVVT--IYYRTIIGLYFLPPSSNT--NDKNIIASVIYTAVTPMLNPFIYSLRNKDIKGALRKLLSRSGAVAHACNLNTLGG---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3Z9I7-1", "uniprot_id": "D3Z9I7_RAT", "id": "D3Z9I7-1", "name": "Olfactory receptor", "aln": "-------------------------------------MRL---KNHS-SVSEFLLLGLPIRAEQSGIFFSMFLAMYLTTVLGNLLIILLIRLDSHLHTPMYFFLSHLAFTDISFSSVTVPKMLTKVPNQNIPITYEGCVSQTYFFIFFADLDSFLITSMAYDRYMAICHP---------LNYTTIMNQSRCATLVAISWIIASACALLHTLLLDQLSFCADHTIPHFFCDLGALLKLSCSDTSLNQLVIFTAGLAAIMLPFLCILISYGHIGFTI-LQVPSTKGICKALSTCGSHLSVVA--LYYGSIIGLYFLPPSNST--INNNIVASVMYTVVTPMLNPFIYSLRNKDMKGALRKLLSKKVEFSN------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGS2-1", "uniprot_id": "OR1J2_HUMAN", "id": "Q8NGS2-1", "name": "Olfactory receptor 1J2", "aln": "-------------------------------------MSP---ENQS-SVSEFLLLGLPIRPEQQAVFFTLFLGMYLTTVLGNLLIMLLIQLDSHLHTPMYFFLSHLALTDISFSSVTVPKMLMDMRTKYKSILYEECISQMYFFIFFTDLDSFLITSMAYDRYVAICHP---------LHYTVIMREELCVFLVAVSWILSCASSLSHTLLLTRLSFCAANTIPHVFCDLAALLKLSCSDIFLNELVMFTVGVVVITLPFMCILVSYGYIGATI-LRVPSTKGIHKALSTCGSHLSVVS--LYYGSIFGQYLFPTVSSS--IDKDVIVALMYTVVTPMLNPFIYSLRNRDMKEALGKLFSRATFFSW------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGS1-1", "uniprot_id": "OR1J4_HUMAN", "id": "Q8NGS1-1", "name": "Olfactory receptor 1J4", "aln": "-------------------------------------MKR---ENQS-SVSEFLLLDLPIWPEQQAVFFTLFLGMYLITVLGNLLIILLIRLDSHLHTPMFFFLSHLALTDISLSSVTVPKMLLSMQTQDQSILYAGCVTQMYFFIFFTDLDNFLLTSMAYDRYVAICHP---------LRYTTIMKEGLCNLLVTVSWILSCTNALSHTLLLAQLSFCADNTIPHFFCDLVALLKLSCSDISLNELVIFTVGQAVITLPLICILISYGHIGVTI-LKAPSTKGIFKALSTCGSHLSVVS--LYYGTIIGLYFLPSSSAS--SDKDVIASVMYTVITPLLNPFIYSLRNRDIKGALERLFNRATVLSQ------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZPB5-1", "uniprot_id": "D3ZPB5_RAT", "id": "D3ZPB5-1", "name": "Olfactory receptor", "aln": "-------------------------------------MQS---RNHS-TVLEFLLVGLTGDAQLQPLIFSLFLCIYLVTVLGNLLIILAVSSDLHLQTPMYFFLSSLSINDICLSTNTIPNMLINMITQNQSITYTGCLTQVWFVLVFTGLENCLLAVMAYDRYVAVCHP---------LRYSTIMNPSCCVLMVLVSLLLSLVFGLLHTLMVLHLSFCKDVEIPHFFCELAQLIKLSCSDTLINNILVYFASCIFGGIPISGIIFSYTHILSAV-LRMPSSGRRYKIFSTCGSHLCVVS--LFYGTILGVYISSSVTDS--PEKSIVASVMYSVVPQMLNPFIYSLRNKDMKQALRKFITRLCAVLSSHVNFTEE----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0R8T8-1", "uniprot_id": "M0R8T8_RAT", "id": "M0R8T8-1", "name": "Olfactory receptor", "aln": "-------------------------------------MDL---KNQT-AVSEFHLLGLTDNHKLLPLIFFMFLSMYLITVLGNLVIILAISSGSQLHTPMYLFLSILSINDICYSTVTIPKMLVNIQAHDDSISYIECLSQICFVSIFCGMENFLLAVMAYDRYVAICKP---------LRYTVIMNPIFCVLMILFSLFFSITDALLHSLMILKLSFCTELEIPHFFCELAQIIKLACSDTFLNNFLIFVAAFVFGGGPVCGIVFSYIYIVSRV-LRMPSSGGKHRAFSTCASHLSVVS--LFYGTGFGVYISSALQDS--LRNTAMASMMYSVVPPLLNPFIYSLRNREMKKALRTLVGRLIYLV-------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A4S6-1", "uniprot_id": "D4A4S6_RAT", "id": "D4A4S6-1", "name": "", "aln": "-------------------------------------MAV---TNLT-YRPQFQLLGLMDGADTHPLLFLLFLSIYLLNALGNLSMVVLVRSDGALCSPMYYFLGHLSLVDVCFTTVTVPRLLVTLLHPGQAMSFQDCFAQMYFFVALGITESYLLAAMSYDRVVAVCRP---------LHYGVVMTPWRCFVLVAASWTVAHLHSLLHTLLISALSYPRSAPVHHFFCDMTVMLSLATSDTSTAETAIFSEGLAVVLTPLILVSLSYARILVAV-LGMQTTGGRHRVFSTCGAHLVVVS--LFFGSVLSVYFRPSFGYS--ARYDRMASVVYAVVTPTLNPFIYSLRNKEVKGALKRGFRWRAAAQDE-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VFY0-1", "uniprot_id": "Q8VFY0_MOUSE", "id": "Q8VFY0-1", "name": "", "aln": "-------------------------------------MAV---TNLT-YKPQFQLLGLMDGTDPHPLLFLLFLSIYLLNALGNLSMVVLVRSDGALCSPMYYFLGHLSLVDVCFTTVTVPRLLATLLHPGQAISFQACFAQMYFFVALGITESYLLAAMSYDRAVAVCRP---------LHYGAVMTPWRCFLLVAASWAVAHLHSLLHTLLISALTYPPSAPVRHFFCDMTVMLSLATSDTSAAETAIFSEGLTVVLTPLLLVSLSYARILVAV-LGIRTTGGRHRVFSTCGAHLVVVS--LFFGSVLSVYFRPSSAYS--ARYDRMASVVYAVVTPTLNPFIYSLRNKEVKSALKRGFRWRAAPQDE-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A286YEU6-1", "uniprot_id": "OR1R1_HUMAN", "id": "A0A286YEU6-1", "name": "Olfactory receptor 1R1", "aln": "-------------------------------------MAP---TNLT-SAPVFLLLGLVDGTDAHPLLFLLCLGIYLLNALSNLSMVALVRSDGALRSPMYYFLGHLSLVDVCFTTVTVPRLLAGLLHPGQAISFQACFAEMYFFVALGITESYLLAAMSYDRPTAACRP---------LRYGALVTPWRCASLVRASWAVTHLHSLLHTLLLSALSYPYPTPVRPFFCDMTVMLSLATSDTSAAETAIFSEGLAVVLAPLLLVFLFLR--AHPG-RGARLAGGRRRAFSTCGAHLVAVAVALFFGSVLSVYFPPSSAYS--ARYDRLASVVYAVITPTLNPFINSLRNKEVKGALKRGLRWRAAPQEA-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGR2-1", "uniprot_id": "OR1L6_HUMAN", "id": "Q8NGR2-1", "name": "Olfactory receptor 1L6", "aln": "MSYFYRLKLMKEAVLVKLPFTSLPLLLQTLSRKSRDMEIK---NYSS-STSGFILLGLSSNPQLQKPLFAIFLIMYLLAAVGNVLIIPAIYSDPRLHTPMYFFLSNLSFMDICFTTVIVPKMLVNFLSETKVISYVGCLAQMYFFMAFGNTDSYLLASMAIDRLVAICNP---------LHYDVVMKPRHCLLMLLGSCSISHLHSLFRVLLMSRLSFCASHIIKHFFCDTQPVLKLSCSDTSSSQMVVMTETLAVIVTPFLCIIFSYLRIMVTV-LRIPSAAGKWKAFSTCGSHLTAVA--LFYGSIIYVYFRPLSMYS--VVRDRVATVMYTVVTPMLNPFIYSLRNKDMKRGLKK-LQDRIYR--------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TRY4-1", "uniprot_id": "Q7TRY4_MOUSE", "id": "Q7TRY4-1", "name": "Olfactory receptor", "aln": "-------------------------------------MLR---ENQS-HMTEFLLLGLTSNPKQQVWLFASFLAMYLVNVIGNSVIIASIQRDARLHTPMYFFLSNLSLVDICFTTVIVPQMLVNLLTQRKTILFAQCLTQMYFFVAFGITDSFLLAAMAIDRYVAICNP---------LHYNTVMSPRRCRLLVVASWAVSHLHSLTHTILMGRLSFCGPNVIHHFFCDVQPLLTLSCSDTSINELLAFTEGSVVIMSPFIFIVVSYIYITRTV-LRVPSGEGRYKVFSTCGSHLTVVA--LFYGTIISVYIRPSSTYS--VTKDRVVTVIYTVVTPMLNPFIYSLRNKDMKQALRK-LAKRTE---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LNM5-1", "uniprot_id": "A0ABK0LNM5_RAT", "id": "A0ABK0LNM5-1", "name": "", "aln": "-------------------------------------MAP---VNQS-VVTMFILQNFVDDPWIQDVLFCLFFALFMMAIAGNGLIIMTIYSSANLHTPMYFFLVNLSLMDVICTVTVLPKVLQSLVA-ENAISYGGCLTQMFVFSWVLGSELLLFSAMAYDRYLAICRP---------LHYGTLMNGRACVALATFVWFTGALNSLVLTCLVLPLSFCGPNLITHFFCEIPSVLMLSCSSTFINDIMTVITDMFLTGLNFLLTMTSYVFIIASI-LRIRSAEGKKRAFSTCSAHLVVVT--LYYSTVLYTYVRPALGTA--GLLDKAVAVLYTTVTPSLNPLIYTLRNKEFKTSFKKLLFPH-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6B0Y0-1", "uniprot_id": "A0A8I6B0Y0_RAT", "id": "A0A8I6B0Y0-1", "name": "", "aln": "-------------------------------------MAP---INQS-VVTMFFLQNFVDDPWIQNVLFCFFFALFVAAIAGNGLIITVIHSSANLHTPMYFFLVNLSLMDVICTVTVLPKVLQSLVA-ENAISYGGCLTQMFVFSWVLGSELLLFSAMAYDRYLAICRP---------LHYGTLMSGRVCIALATFVWFTGALNSLVLTCLVLPLSFCGPNLITHFFCEIPSVLMLSCSPTFINDIMTVIADMFLTGLNFLLTMTSYGFIIASI-LRIRSAEGKKRAFSTCSAHLVVVT--LYYSTVLYTYVRPALGTS--GLLDKVIAVLYTTVTPSLNPLIYTLRNKEFKTSFKKLLFPN-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2K0L2-1", "uniprot_id": "A0A0G2K0L2_RAT", "id": "A0A0G2K0L2-1", "name": "", "aln": "-------------------------------------------MNGT-LVTEFLILGFSEMPHLRVP-LLSFLCLYMAAISGNLLIMVTVSASPALHTPMYFFLVNLAVVDILCTSTILPKLLDIMVG-GRTISYGGCMAQLFFFTWSMGAELLLFSAMAYDRFVAICCP---------LHYSTWMGPRVCAFLAGLVWSISLTNTSVNTSLVLHLPFCSSNVIEHFFCEIPPLLKLSCAPTQLNEVMAFAADVFLAVGNFSVIILSYGFIVTSI-LKIRSTEGKQRAFSTCSAHLFVVT--MYYSTIIYTYIRPASSYS--LNKDKVVSIIYTSVAPTLNPLIYTLRNKDVKVALRKLLSSC-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TRT9-1", "uniprot_id": "Q7TRT9_MOUSE", "id": "Q7TRT9-1", "name": "", "aln": "---------------------------------------M---MNGT-LVTEFLILGFSEMPHLRVPLLFSFLCLYMAAISGNLLIMVTISASPALHTPMYFFLVNLAIVDILCTSTILPKLLDSMMT-GRTISYGGCMAQLFFFTWSLGAELLLFSAMAYDRFVAICCP---------LHYSAWMGPRVCAFLAGIVWTISLTNTSVHTGLMLRLPFCSSNVIEHFFCEIPPLLKLSCAPTQLNEAMAFAADVFLAVGNFSVTILSYGFIVASI-LKIRSAEGKRRAFSTCSAHLIVVT--MYYSTVIYTYIRPSSSYS--LNKDKVVSIIYTSVAPTLNPLIYTLRNKDVKVALRRLLSCC-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGL2-1", "uniprot_id": "Q8VGL2_MOUSE", "id": "Q8VGL2-1", "name": "", "aln": "-------------------------------------------MNGT-LVTEFLILGFSDMPHLRILLFLSFLCLYMAAVSGNLLIMVTISASPTLHTPMYFFLVNLAVVDILCTSTILPKLLDTMVG-GRTISYGGCMAQLFFFTWSLGVELLLFSAMAYDRFVAICCP---------LHYSTWMGPRVCAFLAGIVWAISLTNTSINSSLVLRLPFCSSNVVEHFFCEIPPLLKLSCAPTQLNEAMAFAADVFLAVGNFSVIILSYGFIVASI-LKIRSAEGKQRAFSTCSAHLIVVT--MYYSTVIYTYIRPSSSYS--LNKDKVVSIIYTSVAPTLNPLIYTLRNKDVKVALRRLFSCC-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TS01-1", "uniprot_id": "Q7TS01_MOUSE", "id": "Q7TS01-1", "name": "", "aln": "---------------------------------------M---MNFS-IVSEFMILGLTQKSELQGILFIVFLFIYLVALLGNMLIVVAIIYNTTLHTPMYILLLALAVVDIICTTSIIPKMLGTMLTSKNSISYGGCMSQLFFFTWSLGAEMVLFTTMAYDRYVAICFP---------LRYSTIMNHYTCVGLLSIVMAIAVTNSWVHTGLILRLTFCGPNIIDHFFCEIPPLLALSCSPVRVNEVMVYVADITLAVGDFTLTCISYGFIIAAI-LRIRTTEGKKKAFSTCSSHLMVVS--LYYSPVIYTYIRPASSYT--FDKDKVVAALYTLVTPTLNPIVYSFRNKEMQSGIKKVFAFLKG---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGZ3-1", "uniprot_id": "O13G1_HUMAN", "id": "Q8NGZ3-1", "name": "Olfactory receptor 13G1", "aln": "-------------------------------------------MNHS-VVTEFIILGLTKKPELQGIIFLFFLIVYLVAFLGNMLIIIAKIYNNTLHTPMYVFLLTLAVVDIICTTSIIPKMLGTMLTSENTISYAGCMSQLFLFTWSLGAEMVLFTTMAYDRYVAICFP---------LHYSTIMNHHMCVALLSMVMAIAVTNSWVHTALIMRLTFCGPNTIDHFFCEIPPLLALSCSPVRINEVMVYVADITLAIGDFILTCISYGFIIVAI-LRIRTVEGKRKAFSTCSSHLTVVT--LYYSPVIYTYIRPASSYT--FERDKVVAALYTLVTPTLNPMVYSFQNREMQAGIRKVFAFLKH---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LI97-1", "uniprot_id": "A0ABK0LI97_RAT", "id": "A0ABK0LI97-1", "name": "Olfactory receptor", "aln": "------------------------------------------------MVIEFLFSVFPPLHEGGLLFFILLILVYAFIISGNLVIFVAVQLDLALHTPMYFFISVLSFLEIWYTTTTIPKMLSSLVSEKKTISLGGCLMQMYFFHSLGITEGCVLTAMSIDRYIAICYP---------LRYPTIMTSKLCIQLTAGSCFCGFLLVLPEIAWIATLPFCGSNKIHQIFCDFTPVLRLACTDTSLVV-IVDAIHAVEILASFLVIALSYIRIIMVI-LGMPSAEGRHKAFSTCAAHLAVFL--LFFGSVAVMYLRFSATYS--VFWDTVIAVTFVILAPFLNPIIYSLRNKEMKDAIGRLFH-RKRDARAQK---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGW6-1", "uniprot_id": "OR6K6_HUMAN", "id": "Q8NGW6-1", "name": "Olfactory receptor 6K6", "aln": "---------MKQYSVGNQHSNYRSLLFPFLCSQMTQLTAS---GNQT-MVTEFLFSMFPHAHRGGLLFFIPLLLIYGFILTGNLIMFIVIQVGMALHTPLYFFISVLSFLEICYTTTTIPKMLSCLISEQKSISVAGCLLQMYFFHSLGITESCVLTAMAIDRYIAICNP---------LRYPTIMIPKLCIQLTVGSCFCGFLLVLPEIAWISTLPFCGSNQIHQIFCDFTPVLSLACTDTFLVV-IVDAIHAAEIVASFLVIALSYIRIIIVI-LGMHSAEGHHKAFSTCAAHLAVFL--LFFGSVAVMYLRFSATYS--VFWDTAIAVTFVILAPFFNPIIYSLKNKDMKEAIGRLFHYQKRAGWAGK---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6A5L7-1", "uniprot_id": "A0A8I6A5L7_RAT", "id": "A0A8I6A5L7-1", "name": "Olfactory receptor", "aln": "-------------------------------------MRI---NRTT-SVTEFLFSGLPEFEDGRFLFFIPLFFIYVFIVIGNLIVFFAVRMDTRLHNPMYNFISIFSFLEIWYTTATIPKMLSNLISKRRTISLIGCLLQMYFFHSLGNSEGILLTTMAIDRYIAICNP---------LRYPTIMTPRLCAQLSAGSCIFGFLVLLPEIAWISTLPFCGPNQIHQIFCDFEPVLRLACTDTSMIL-VEDVVHAVAIIFSVLVIAFSYIRIITVI-LRIPSGEGRRKAFSTCAAHLGVFL--MFYGSVSLMYLRFSATFP--PVLDTAIALMFAVLAPFFNPIIYSLRNKDMKTAIKKLLSSPTMLPTSAS---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGY3-1", "uniprot_id": "OR6K3_HUMAN", "id": "Q8NGY3-1", "name": "Olfactory receptor 6K3", "aln": "--------------------MCWTMPSPFTG-SSTRNMES---GNQS-TVTEFIFTGFPQLQDGSLLYFFPLLFIYTFIIIDNLLIFSAVRLDTHLHNPMYNFISIFSFLEIWYTTATIPKMLSNLISEKKAISMTGCILQMYFFHSLENSEGILLTTMAIDRYVAICNP---------LRYQMIMTPRLCAQLSAGSCLFGFLILLPEIVMISTLPFCGPNQIHQIFCDLVPVLSLACTDTSMIL-IEDVIHAVTIIITFLIIALSYVRIVTVI-LRIPSSEGRQKAFSTCAGHLMVFP--IFFGSVSLMYLRFSDTYP--PVLDTAIALMFTVLAPFFNPIIYSLRNKDMNNAIKKLFCLQKVLNKPGG---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AP46-1", "uniprot_id": "A0A8I6AP46_RAT", "id": "A0A8I6AP46-1", "name": "Olfactory receptor", "aln": "-------------------------------------MDH---VNCT-WNWIFILAGFNTSGTLQQLAVFGTLCIYLLTLAGNLFIIVLVQADSGLSTPMYFFISVLSFLEIWYVSTTVPTLLHTLLHGHSPIPSAACFIQLYVFHSLGMTECYLLGVMALDRYLAICRP---------LHYHSLMSRQVQRELVLITWVAGFSAALVPAGLTATLPYC-LKEVAHYFCDLGPVMQLACVDTSWHARVYIAVIGMINTCNLVFILGLYGGIVKAV-LRLPSAASRAKAFSTCSSHITVVT--LFFGSAFIVYVGPPEIRA--EGRGKLIALVYTLFTPFFNPIIYTLRNKEVKAAFKRVTQRIKGVLG------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZIK6-1", "uniprot_id": "D3ZIK6_RAT", "id": "D3ZIK6-1", "name": "Olfactory receptor", "aln": "-------------------------------------MDH---VNYT-WTRTFILAGFTTSGTLQQLSVFGTLCIYLLTIAGNIFIIVLVQADSGLSTPMYFFISVLSFLEIWYVSTSVATLLHTLLHGHSPIPSAACFIQLYVFHSLGMTECYLLSVMALDRYLAICRP---------LHYHALMSRQVKIQLVLITWVAGFSVALVPAGLTASLPYC-LKEVAHYLCDLEPVIRLACVDTSWHARVYITVIGIIITCNLVSILGLYGGIAKAV-LRLPSAASRAKAFSTCSSHITVVT--LFYGSAFIVYVGPPEIRA--EGRDKLIALVYTLFTPFFNPIIYTLRNKEVKAAFKRVTQRIQGVLS------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q8M2-1", "uniprot_id": "E9Q8M2_MOUSE", "id": "E9Q8M2-1", "name": "Olfactory receptor", "aln": "-------------------------------------MDH---VNYT-WTRTFILAGFTTSGTLQHLAVFGTLCIYLLTLAGNLFIIVLIQADSGLSTPMYFFISVLSFLELWYVSTTVPTLLHTLLHGPSPIPSSACFVQLYVFHSLGMTECYLLGVMALDRYLAICRP---------LHYHALMSRQVQKQLVGVTWLAGFSAALVPAGLTASLPYC-LKEVAHYFCDLAPVMQLACVDTSWHARLYIAVIGMINTCNLTFILGLYGGIVRAV-LKLPSAASRAKAFSTCSSHITVVT--LFFGSAFIVYVGPPEIRA--EGRDKLIALVYTLLTPFFNPIIYTLRNKEVKEAFKRVTQRINAVLK------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TRV9-1", "uniprot_id": "Q7TRV9_MOUSE", "id": "Q7TRV9-1", "name": "Olfactory receptor", "aln": "-------------------------------------MDH---VNYT-WTRTFILAGFTTSGALRPLAFLGTLCIYLLTLAGNLFIIVLVQADSGLSTPMYFFISVLSFLELWYVSTTVPTLLHTLLHGHSPIPSSACFVQLYVFHSLGMTECYLLGVMALDRYLAICRP---------LHYHALMSRQVQLWLAGATWVAGFSAALVPACLTASLPYC-LKEIAHYFCDLAPLMRLACVSTRWHARVHGAVIGVATGCNFVLILGLYGGILTAV-LKLPSAASRAKAFSTCSSHMTVVA--LFYASAFTVYVGSPQSRP--EGTDKLIALVYALLTPFLNPIIYSLRNKEVKEAVKRVSEKIRTLLRDT----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9I8Z0-1", "uniprot_id": "Q9I8Z0_DANRE", "id": "Q9I8Z0-1", "name": "", "aln": "-------------------MYYFAYFLTFYFQPVQNKADMSLSQNSSSVYPEYFFIIGLSGIHNSNYYYMFLCITYFVTVTGNSLVLLLIALYRSLHSPKYIGVFNLALADFGETNALIPNMMKTFLFDSQYISYNACLANMFFVHFFSTVQSFTLVVLAYDRFIAIFLP---------LRYHAIVNYTFMYFVFSIIWVFNASIVAFAVSLITRLSFCESNKVNGYYCDYGPVYRLACNDNSICASMAQLSAALYVVAPVIIIVLSYLGIFLAL-SKITTWEGRLKALKTCVSHLLLVG--SFFLPIICIFIATSTNSLS-LNARVISTSLAHALPPMLHPIIYVLNTAEIKDIIIKIVRNKCLPVRKNILKLRK----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : .* :. * : : :: : . : : *. : : :: . * * : : : : : : :: : :.** *: : : . . *:: :.. :. ", "identical_positions": 9, "similar_positions": 43, "identity": "2.2%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010308-14", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TQQ0-1", "uniprot_id": "OR4E2_MOUSE", "id": "Q7TQQ0-1", "name": "Olfactory receptor 4E2", "aln": "--------------------------------------MGALNQT-RVTEFIFLGLTDNWVLEILFFVPFTVTYMLTLLGNFLIVVTIVFTPRLHNPMYFFLSNLSFIDICHSSVTVPKMLEGLLLERKTISFDNCIAQLFFLHLFACSEIFLLTIMAYDRYVAICIP---------LHYSNVMNMKVCVQLVFALWLGGTIHSLVQTFLTIRLPYCGPNIIDSYFCDVPPVIKLACTDTYLTGILIVSNSGTISLVCFLALVTS--YTVILFSLRKQSAEGRRKALSTCSAHFMVVA--LFFGPCIFLYTRP----DSSFS---IDKVVSVFYTVVTPLLNPLIYTLRNEEVKTAMKHLRQRRICS--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ADC0-1", "uniprot_id": "D4ADC0_RAT", "id": "D4ADC0-1", "name": "Olfactory receptor", "aln": "--------------------------------------MGALNQT-RVTEFVFLGLTDNWVLEILFFIPFTVTYVLTLLGNVLIVVTIVFTPRLHNPMYFFLSNLSFIDICHSSVTVPKMLEGLLLVRKTISFDNCIAQLFFLHLFACAEIFLLTIMAYDRYVAICIP---------LHYPNVMNMKVCVQLVFALWLGGTVHSLVQTFLTIRLPYCGPNTIDSYFCDVPPVIKLACTDTYLTGILIVSNSGTISLVCFLALVTS--YTVILFSLRKQSAEGRRKALSTCSAHFMVVA--LFFGPCIFIYTWP----DTSFS---IDKVVSVFYTVVTPLLNPLIYTLRNEEVKTSMKHLRQRRICS--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGC2-1", "uniprot_id": "OR4E2_HUMAN", "id": "Q8NGC2-1", "name": "Olfactory receptor 4E2", "aln": "--------------------------------------MDSLNQT-RVTEFVFLGLTDNRVLEMLFFMAFSAIYMLTLSGNILIIIATVFTPSLHTPMYFFLSNLSFIDICHSSVTVPKMLEGLLLERKTISFDNCITQLFFLHLFACAEIFLLIIVAYDRYVAICTP---------LHYPNVMNMRVCIQLVFALWLGGTVHSLGQTFLTIRLPYCGPNIIDSYFCDVPLVIKLACTDTYLTGILIVTNSGTISLSCFLAVVTS--YMVILVSLRKHSAEGRQKALSTCSAHFMVVA--LFFGPCIFIYTRP----DTSFS---IDKVVSVFYTVVTPLLNPFIYTLRNEEVKSAMKQLRQRQVFFTKSYT---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R0K4-1", "uniprot_id": "Q9R0K4_MOUSE", "id": "Q9R0K4-1", "name": "Olfactory receptor", "aln": "-----------------------------------MEKAVLINETSVMS-FRLTGLSTNPLVQMAVFFIFLIFYVLTLVGNILIVITIIYDRRLHTPMYFFLSNLSFIDVCHSTVTVPKMLSDTFSEEKLISFDACVVQMFFLHLFACTEIFLLTVMAYDRYVAICKP---------LQYMTIMNWKVCMMLAAALWTGGTIHSISLTSLTIKLPYCGPDEIDNFFCDVPQVIKLACTDTHIIEILIVSNSGLISVVCFVVLVVS--YAVILVSLRQQISDGKRKALSTCAAHLTVVT--LFLGHCIFIYSRP----STSLP---EDKVVSVFFTAVTPLLNPIIYTLRNEDMKSALNKLIKRREK---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C645-1", "uniprot_id": "OR4E1_HUMAN", "id": "P0C645-1", "name": "Olfactory receptor 4E1", "aln": "-----------------------------------MEEAILLNQTSLVTYFRLRGLSVNHKARIAMFSMFLIFYVLTLIGNVLIVITIIYDHRLHTPMYFFLSNLSFIDVCHSTVTVPKMLRDVWSEEKLISFDACVTQMFFLHLFACTEIFLLTVMAYDRYVAICKP---------LQYMIVMNWKVCVLLAVALWTGGTIHSIALTSLTIKLPYCGPDEIDNFFCDVPQVIKLACIDTHVIEILIVSNSGLISVVCFVVLVVS--YAVILVSLRQQISKGKRKALSTCAAHLTVVT--LFLGHCIFIYSRP----STSLP---EDKVVSVFFTAVTPLLNPIIYTLRNEEMKSALNKLVGRKERKEEK-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VG74-1", "uniprot_id": "Q8VG74_MOUSE", "id": "Q8VG74-1", "name": "Olfactory receptor", "aln": "----------------------------------------MENYT-RVKELIFLGLTQSQEVSMVLFLFLLLVYVTTLLGNLLIMVTVTCESRLHTPMYFLLRNLSVADICFSSITAPKVLVDLLSDRKTISFNGCLTQMFFFHLIGGVDVFSLSVMALDRYVAISKP---------LHYVTIMSRGRCIGLIVASWVGGFAHSIVQISLLLTLPFCGPNVLDTFYCDVPQVIKLACTDIFVLELLMISNNGLVATLWFVLLVVS--YTVILMMLRSHSGEGRKKAISTCTSHITVVT--LHFVPCIYVYARP----FTALP---TDKAISVTFTVISPLLNPLIYTLRNQEMKSAMRRLRKRLEPFDREEQ---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2I3BQG5-1", "uniprot_id": "A0A2I3BQG5_MOUSE", "id": "A0A2I3BQG5-1", "name": "Olfactory receptor", "aln": "--------------------------MSAPTSVYQGSNSVLLNQT-LVTEFLLLGVTDIQELNPILFVTVLAMYFVNVAGNGAILLIVISDPRLHSPMYFFLGNLACLDICFSTVTVPKILDNFFSTSKAISFLGCITQLYFFHLLGSTEALLLAVMAFDRFVAICRP---------LHYPSIMNGQVCIQVAISIWAIPFVHALVHSILTSQLNFCGSNQIHHFFCDVKPLLELACGNTELNRWLLNTFTGTFAIGLFFLTFLSYFYIITYLFLKTRSCSMLHKALSTCASHFMVVM--IFYAPVLFIYINP--DSGSSLE---KDRIIAVMYTVVTPALNPLIYTLRNKEVRGALNRKLRILL----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2I3BRX0-1", "uniprot_id": "A0A2I3BRX0_MOUSE", "id": "A0A2I3BRX0-1", "name": "Olfactory receptor", "aln": "--------------------------MSAPTSVSQEGNSVLLNHT-LVTEFLLLGVTDIQELNPILFVTVLAMYFVNVAGNGAILMIVISDPRLHLPMYFFLGNLACLDICFSTVTVPKMLENFFSTSKAISFLGCITQLHFFHFLGSTEALLLTVMAFDRFVAICRP---------LHYPAIMNSQVCIQVAISIWAIPFLHALVHSILTSQLNFCGSNHIHHFFCDVKPLLELACGNTELNRWLLNTLTGTVAIGLFFLTFLSYFYIVTYLFLKTRSCSMLHKALSTCASHFMVVM--IFYAPVLFIYINP--DSGSSLE---KDRIIAVMYTVVTPALNPLIYTLRNKEVRGALNRKIRILL----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58182-1", "uniprot_id": "O12D2_HUMAN", "id": "P58182-1", "name": "Olfactory receptor 12D2", "aln": "----------------------------------------MLNTT-SVTEFLLLGVTDIQELQPFLFVVFLTIYFISVTGNGAVLMIVISDPRLHSLMYFFLGNLSYLDICYSTVTLPKMLQNFLSTHKAISFLGCISQLHFFHSLGSTESMLFAVMAFDLSVAICKP---------LRYTVIMNPQLCTQMAITIWVIGFFHALLHSVMTSRLNFCGSNRIHHFLCDIKPLLKLACGNTELNQWLLSTVTGTIAMGPFFLTLLSYFYIITYLFFKTRSCSMLCKALSTCASHFMVVI--LFYAPVLFTYIHP--ALESFMD---QDRIVAIMYTVVTPVLNPLIYTLRNKEVKGALGRVIRRL-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VG96-1", "uniprot_id": "Q8VG96_MOUSE", "id": "Q8VG96-1", "name": "Olfactory receptor", "aln": "----------------------------------------MENST-SVDEFLLLGLTSVQKLQPIIFVMFLTIYLLNLVGNGVILMIVTLERRLHSPMYFFLGNLSCLDICYSSVTLPKVLINLLSRRRAISFLGCITQLYFFHFLGSTEAILLAVMAFDRFVAICSP---------LRYTAIMNPQLCILLAATAWFTSFFYALLHSVMTAHLNFCHSHKLSHFFCDVKPLLEVACGNTVLNQWLLSVVTGSISMGAFLLILLSYFYIIAFLLFKNRSCRMLKKALSTCTSHFMVVC--LFYGPVGFTYIRPATASASSMS---EDRVVAIIYSAVTPVLNPLIYTLRNKEVMLALKKNFGKKLFKGN------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGF7-1", "uniprot_id": "O12D3_HUMAN", "id": "Q9UGF7-1", "name": "Olfactory receptor 12D3", "aln": "----------------------------------------MENVT-TMNEFLLLGLTGVQELQPFFFGIFLIIYLINLIGNGSILVMVVLEPQLHSPMYFFLGNLSCLDISYSSVTLPKLLVNLVCSRRAISFLGCITQLHFFHFLGSTEAILLAIMAFDRFVAICNP---------LRYTVIMNPQVCILLAAAAWLISFFYALMHSVMTAHLSFCGSQKLNHFFYDVKPLLELACSDTLLNQWLLSIVTGSISMGAFFLTLLSCFYVIGFLLFKNRSCRILHKALSTCASHFMVVC--LFYGPVGFTYIRP--ASATSMI---QDRIMAIMYSAVTPVLNPLIYTLRNKEVMMALKKIFGRKLFKDWQQHH--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LI97-1", "uniprot_id": "A0ABK0LI97_RAT", "id": "A0ABK0LI97-1", "name": "Olfactory receptor", "aln": "----------------------------------------------MVIEFLFSVFPPLHEGGLLFFILLILVYAFIISGNLVIFVAVQLDLALHTPMYFFISVLSFLEIWYTTTTIPKMLSSLVSEKKTISLGGCLMQMYFFHSLGITEGCVLTAMSIDRYIAICYP---------LRYPTIMTSKLCIQLTAGSCFCGFLLVLPEIAWIATLPFCGSNKIHQIFCDFTPVLRLACTDTSLVV-IVDAIHAVEILASFLVIALSY-IRIIMVILGMPSAEGRHKAFSTCAAHLAVFL--LFFGSVAVMYLRF--SATYSVF---WDTVIAVTFVILAPFLNPIIYSLRNKEMKDAIGRLFH-RKRDARAQK---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGW6-1", "uniprot_id": "OR6K6_HUMAN", "id": "Q8NGW6-1", "name": "Olfactory receptor 6K6", "aln": "----------MKQYSVGNQHSNYRSLLFPFLCSQMTQLTASGNQT-MVTEFLFSMFPHAHRGGLLFFIPLLLIYGFILTGNLIMFIVIQVGMALHTPLYFFISVLSFLEICYTTTTIPKMLSCLISEQKSISVAGCLLQMYFFHSLGITESCVLTAMAIDRYIAICNP---------LRYPTIMIPKLCIQLTVGSCFCGFLLVLPEIAWISTLPFCGSNQIHQIFCDFTPVLSLACTDTFLVV-IVDAIHAAEIVASFLVIALSY-IRIIIVILGMHSAEGHHKAFSTCAAHLAVFL--LFFGSVAVMYLRF--SATYSVF---WDTAIAVTFVILAPFFNPIIYSLKNKDMKEAIGRLFHYQKRAGWAGK---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6A5L7-1", "uniprot_id": "A0A8I6A5L7_RAT", "id": "A0A8I6A5L7-1", "name": "Olfactory receptor", "aln": "--------------------------------------MRINRTT-SVTEFLFSGLPEFEDGRFLFFIPLFFIYVFIVIGNLIVFFAVRMDTRLHNPMYNFISIFSFLEIWYTTATIPKMLSNLISKRRTISLIGCLLQMYFFHSLGNSEGILLTTMAIDRYIAICNP---------LRYPTIMTPRLCAQLSAGSCIFGFLVLLPEIAWISTLPFCGPNQIHQIFCDFEPVLRLACTDTSMIL-VEDVVHAVAIIFSVLVIAFSY-IRIITVILRIPSGEGRRKAFSTCAAHLGVFL--MFYGSVSLMYLRF--SATFPPV---LDTAIALMFAVLAPFFNPIIYSLRNKDMKTAIKKLLSSPTMLPTSAS---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGY3-1", "uniprot_id": "OR6K3_HUMAN", "id": "Q8NGY3-1", "name": "Olfactory receptor 6K3", "aln": "---------------------MCWTMPSPFTG-SSTRNMESGNQS-TVTEFIFTGFPQLQDGSLLYFFPLLFIYTFIIIDNLLIFSAVRLDTHLHNPMYNFISIFSFLEIWYTTATIPKMLSNLISEKKAISMTGCILQMYFFHSLENSEGILLTTMAIDRYVAICNP---------LRYQMIMTPRLCAQLSAGSCLFGFLILLPEIVMISTLPFCGPNQIHQIFCDLVPVLSLACTDTSMIL-IEDVIHAVTIIITFLIIALSY-VRIVTVILRIPSSEGRQKAFSTCAGHLMVFP--IFFGSVSLMYLRF--SDTYPPV---LDTAIALMFTVLAPFFNPIIYSLRNKDMNNAIKKLFCLQKVLNKPGG---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AP46-1", "uniprot_id": "A0A8I6AP46_RAT", "id": "A0A8I6AP46-1", "name": "Olfactory receptor", "aln": "--------------------------------------MDHVNCT-WNWIFILAGFNTSGTLQQLAVFGTLCIYLLTLAGNLFIIVLVQADSGLSTPMYFFISVLSFLEIWYVSTTVPTLLHTLLHGHSPIPSAACFIQLYVFHSLGMTECYLLGVMALDRYLAICRP---------LHYHSLMSRQVQRELVLITWVAGFSAALVPAGLTATLPYC-LKEVAHYFCDLGPVMQLACVDTSWHARVYIAVIGMINTCNLVFILGLY-GGIVKAVLRLPSAASRAKAFSTCSSHITVVT--LFFGSAFIVYVGP--PEIRAEG---RGKLIALVYTLFTPFFNPIIYTLRNKEVKAAFKRVTQRIKGVLG------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZIK6-1", "uniprot_id": "D3ZIK6_RAT", "id": "D3ZIK6-1", "name": "Olfactory receptor", "aln": "--------------------------------------MDHVNYT-WTRTFILAGFTTSGTLQQLSVFGTLCIYLLTIAGNIFIIVLVQADSGLSTPMYFFISVLSFLEIWYVSTSVATLLHTLLHGHSPIPSAACFIQLYVFHSLGMTECYLLSVMALDRYLAICRP---------LHYHALMSRQVKIQLVLITWVAGFSVALVPAGLTASLPYC-LKEVAHYLCDLEPVIRLACVDTSWHARVYITVIGIIITCNLVSILGLY-GGIAKAVLRLPSAASRAKAFSTCSSHITVVT--LFYGSAFIVYVGP--PEIRAEG---RDKLIALVYTLFTPFFNPIIYTLRNKEVKAAFKRVTQRIQGVLS------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q8M2-1", "uniprot_id": "E9Q8M2_MOUSE", "id": "E9Q8M2-1", "name": "Olfactory receptor", "aln": "--------------------------------------MDHVNYT-WTRTFILAGFTTSGTLQHLAVFGTLCIYLLTLAGNLFIIVLIQADSGLSTPMYFFISVLSFLELWYVSTTVPTLLHTLLHGPSPIPSSACFVQLYVFHSLGMTECYLLGVMALDRYLAICRP---------LHYHALMSRQVQKQLVGVTWLAGFSAALVPAGLTASLPYC-LKEVAHYFCDLAPVMQLACVDTSWHARLYIAVIGMINTCNLTFILGLY-GGIVRAVLKLPSAASRAKAFSTCSSHITVVT--LFFGSAFIVYVGP--PEIRAEG---RDKLIALVYTLLTPFFNPIIYTLRNKEVKEAFKRVTQRINAVLK------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TRV9-1", "uniprot_id": "Q7TRV9_MOUSE", "id": "Q7TRV9-1", "name": "Olfactory receptor", "aln": "--------------------------------------MDHVNYT-WTRTFILAGFTTSGALRPLAFLGTLCIYLLTLAGNLFIIVLVQADSGLSTPMYFFISVLSFLELWYVSTTVPTLLHTLLHGHSPIPSSACFVQLYVFHSLGMTECYLLGVMALDRYLAICRP---------LHYHALMSRQVQLWLAGATWVAGFSAALVPACLTASLPYC-LKEIAHYFCDLAPLMRLACVSTRWHARVHGAVIGVATGCNFVLILGLY-GGILTAVLKLPSAASRAKAFSTCSSHMTVVA--LFYASAFTVYVGS--PQSRPEG---TDKLIALVYALLTPFLNPIIYSLRNKEVKEAVKRVSEKIRTLLRDT----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGK1-1", "uniprot_id": "Q8VGK1_MOUSE", "id": "Q8VGK1-1", "name": "Olfactory receptor", "aln": "------------------------------------ME-----NESSVSEFFLQGISGFSEQQQLLYGLFLCMYLVTLTGNVLIILAIGSDPHLHTPMYFFLANLSFADMGLISSTVTKMLFNVQTRCHTISYTGCLTQMYFFLMFGDLDSFLLAVMAYDRYVAICHP---------LHYSTIMSARVCALMLALCWVLTNIVALTHTLLMARLSFCVVGEIAHFFCDITPVLKLSCSDTHVNELMVFALGGTVLMVPFVCIVISYIHIVFAI-LKVRTPGGGTKAFSTCSSHLCVVC--VFYGTLFSAYLCP--PSVVST---EKDVAAAAMYTVVTPMLNPFIYSLRNKDMKGALKRLLCHRKFLS-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGK0-1", "uniprot_id": "Q8VGK0_MOUSE", "id": "Q8VGK0-1", "name": "Olfactory receptor", "aln": "------------------------------------ME-----NQSSVSEFFLRGISGFPEQQQLLYGLFLCMYLVTLTGNVLIILAISCDPHLHTPMYFFLANLSFADMGLISSAVTKMLFNVQTQRHTISYTGCLTQMYLFMMFGDLDSFFLAVMAYDRYVAICHP---------LHYSTIMSARVCALMLALCWVLTNIVALTHTLLMTRLSFCVVGEIAHFFCDITSVMKLSCSDTHVNELVLSGFGGTVLMVPFVSIVISYVRIVFAV-LRVQTSGGSSKAFSTCSSHLCVVC--VFYGTLFSVYLFP--SSGETT---EKDVVAAAMYTVVTPMLNPFIYSLRNKDMKGALKRLLCHRRKFSP------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGS0-1", "uniprot_id": "OR1N1_HUMAN", "id": "Q8NGS0-1", "name": "Olfactory receptor 1N1", "aln": "------------------------------------ME-----NQSSISEFFLRGISAPPEQQQSLFGIFLCMYLVTLTGNLLIILAIGSDLHLHTPMYFFLANLSFVDMGLTSSTVTKMLVNIQTRHHTISYTGCLTQMYFFLMFGDLDSFFLAAMAYDRYVAICHP---------LCYSTVMRPQVCALMLALCWVLTNIVALTHTFLMARLSFCVTGEIAHFFCDITPVLKLSCSDTHINEMMVFVLGGTVLIVPFLCIVTSYIHIVPAI-LRVRTRGGVGKAFSTCSSHLCVVC--VFYGTLFSAYLCP--PSIASE---EKDIAAAAMYTIVTPMLNPFIYSLRNKDMKGALKRLFSHRSIVSS------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VGJ8-1", "uniprot_id": "Q8VGJ8_MOUSE", "id": "Q8VGJ8-1", "name": "Olfactory receptor", "aln": "------------------------------------MGKISRVNQSVASDFLLLGLSEQPGEQPLLFGIFLGMYLVTMVGNLLIIFVISSDAHLHTPMYFFLANLSLTDACFTSASVPKMLANIYTQSQTISYSGCLTQLYFLLMFGGLDNCLLAVMAYDRYVAICQP---------LHYSTAMSPQLCALMLCTCWVLTNCPALMHTLLLTRVAFCAHTAIPHFYCDPSALLKLACSDTHINELMIITMGLVFLAVPLMLIVFSYVCISWAV-LGIPSSGGRWKAFSTCGSHLTVVL--LFYGSLMGVYLLP--PSTHST---ERESRAAVLYMIVIPMLNPFIYSLRNRDMKEAMGKLFGGGKTVFLL-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGR9-1", "uniprot_id": "OR1N2_HUMAN", "id": "Q8NGR9-1", "name": "Olfactory receptor 1N2", "aln": "------------------------------------MGKPGRVNQTTVSDFLLLGLSEWPEEQPLLFGIFLGMYLVTMVGNLLIILAISSDPHLHTPMYFFLANLSLTDACFTSASIPKMLANIHTQSQIISYSGCLAQLYFLLMFGGLDNCLLAVMAYDRYVAICQP---------LHYSTSMSPQLCALMLGVCWVLTNCPALMHTLLLTRVAFCAQKAIPHFYCDPSALLKLACSDTHVNELMIITMGLLFLTVPLLLIVFSYVRIFWAV-FVISSPGGRWKAFSTCGSHLTVVL--LFYGSLMGVYLLP--PSTYST---ERESRAAVLYMVIIPTLNPFIYSLRNRDMKEALGKLFVSGKTFFL------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TQU7-1", "uniprot_id": "Q7TQU7_MOUSE", "id": "Q7TQU7-1", "name": "", "aln": "------------------------------------MAP---ENQTTVLEFHLMGLSEDPDLQTILFGLFLSMYLVTVFGNLLIILAIISDSHLHTPMYFFLCNLSLVDIFFCSTTVPKMLVNIQTQSRAISFTGCLVQMYAFHLFGTIDSFLLAVMAIDRLVAIAYP---------LRYSVLMSPHVCALLVGGTWVITNLQSLVHTCLMAQLTFCARSEIPHFFCDLMPLLKLSCSDTHINELVIFAFGIVMGLSPLSCILVSYICIFRAV-FRIPSAQGKWKAFSTCGSHLTVVS--LFYGTIFTGYLLP--ASPSSS---QKDKAAALMFGVVIPTLNPFIYSLRNKDMKAALRKLGSKAVS----------------------------------FQS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60431-1", "uniprot_id": "OR1I1_HUMAN", "id": "O60431-1", "name": "Olfactory receptor 1I1", "aln": "------------------------------------MEP---EKQTEISEFFLQGLSEKPEHQTLLFTMFLSTYLVTIIGNALIILAIITDSHLHTPMYFFLFNLSLVDTLLSSTTVPKMLANIQAQSRAIPFVGCLTQMYAFHLFGTMDSFLLAVMAIDRFVAIVHP---------QRYLVLMCSPVCGLLLGASWMITNLQSLIHTCLMAQLTFCAGSEISHFFCDLMPLLKLSGSDTHTNELVIFAFGIVVGTSPFSCILLSYIRIFWTV-FKIPSTRGKWKAFSTCGLHLTVVS--LSYGTIFAVYLQP--TSPSSS---QKDKAAALMCGVFIPMLNPFIYSIRNKDMKAALGKLIGKVAVPCPRPEQLLDVYHVPGSLLAARDTEMHPIPYPGGVQSLAGNRDME", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH06-1", "uniprot_id": "OR1P1_HUMAN", "id": "Q8NH06-1", "name": "Olfactory receptor 1P1", "aln": "-------------------------MGLTQDFFPPTSELLEGGNQTSTFEFLLWGLSDQPQQQHIFFLLFLWMYVVTVAGNLLIVLAIGTDTHLHTPMYFFLASLSCADIFSTSTTVPKALVNIQTQSRSISYAGCLAQLYFFLTFGDMDIFLPATMAYDRYVAICHL---------LHYMMIMSLHRCAFLVTACWTLTSLLAMTRTFLIFRLSLCSK-ILPGFFCDLGPLMKVSCSDAQVNELVLLFLGGAVILIPFMLILVSYIRIVSAI-LRAPSAQGRRKAFSTCDSHLVVVA--LFFGTVIRAYLCP--SSSSSNS-VKEDTAAAVMYTVVTPLLNPFIYSMRNKDMKAAVVRLLKGRVSFSQGQ----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGA1-1", "uniprot_id": "OR1M1_HUMAN", "id": "Q8NGA1-1", "name": "Olfactory receptor 1M1", "aln": "------------------------------------MEP---RNQTSASQFILLGLSEKPEQETLLFSLFFCMYLVMVVGNLLIILAISIDSHLHTPMYFFLANLSLVDFCLATNTIPKMLVSLQTGSKAISYPCCLIQMYFFHFFGIVDSVIIAMMAYDRFVAICHP---------LHYAKIMSLRLCRLLVGALWAFSCFISLTHILLMARLVFCGSHEVPHYFCDLTPILRLSCTDTSVNRIFILIVAGMVIATPFVCILASYARILVAI-MKVPSAGGRKKAFSTCSSHLSVVA--LFYGTTIGVYLCP--SSVLTT---VKEKASAVMYTAVTPMLNPFIYSLRNRDLKGALRKLVNRKITSSS------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VFM9-1", "uniprot_id": "OR1M1_MOUSE", "id": "Q8VFM9-1", "name": "Olfactory receptor 1M1", "aln": "------------------------------------MEP---QNHTSASEFILLGLSEKPDHDPVLFSLFLCMYMITVVGNLLIILAISFDSHLHTPMYFFLANLSLVDFCLATNTVPKMLVNIQTRNKSISYPCCLTQMYFFHFFGIMDSVLIAVMAYDRFVAICHP---------LHYSTIMSPRLCGLLVGVPWVYSCFISLTHILLMARLVFCGKNELPHYFCDLTPLLRLSCTDTTVNKIFVLIVAGMVIATPFVCILASYARIIVAI-MKVPSAGGRKKAFSTCSSHLSVVA--LFYGTTIGVYLCP--SSVRTA---VKEKASAVMYTAVTPMLNPFIYSLRNRDLKGALKKIINRKISTSS------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGG9-1", "uniprot_id": "Q8VGG9_MOUSE", "id": "Q8VGG9-1", "name": "Olfactory receptor", "aln": "------------------------------------MDG---DNQTIVTEFILLGLTRQSEKEEVVFGLFLWMYLVTISGNLLIILAISCDPHLHTPMYFFLANLSSVDISAPSVIVPKALVNHMLGSKSISYTGCMTQIYFFITFSNMDGFLLSVMAYDRYVAICHP---------LHYTMMMRPRLCVLLVAISWAITNLHALLHTLLMVRLTFCSHNAVHHFFCDPYPILKLSCSDTFINDLMVFTIGGLVFMTPFTCIIVSYAYIFSKV-LKLKSAHGIRKALSTCGSHLTVVS--LFYGAILGIYMHP--SSTYTVQ----DTVATVIFTVVTPMVNPFIYSLRNRDIKGALRKIILRS-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGH1-1", "uniprot_id": "Q8VGH1_MOUSE", "id": "Q8VGH1-1", "name": "Olfactory receptor", "aln": "------------------------------------MDG---DNETMVAEFLLLGLSGKSEQEEVVFGMFLGMYLVTISGNLLIILAISCDPHLHTPMYFFLANLSSVDICFSSVTVPKALVNHVLGSKSISYTECMIQIYFFITFINMDGFLLSVMAYDRYVAICHP---------LHYTMMMRSRLCVLLVAISWVITNLHALLHTLLMVRLTFCSHNAVHHFFCDPYPILKLSCSDTFINDLMVFTVGGVIFLTPFSCIVVSYVYIFSKV-LKIPSARGIRKALSTCGSHLTVVS--LFYGAILGVYMRP--SSSYSLQ----DTVATVIFTVVTPLVNPFIYSLRNQDMKGALRKIMLRS-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NHA8-1", "uniprot_id": "OR1FC_HUMAN", "id": "Q8NHA8-1", "name": "Putative olfactory receptor 1F12P", "aln": "------------------------------------MEG---KNQTNISEFLLLGFSSWQQQQVLLFALFLCLYLTGLFGNLLILLAIGSDHCLHTPMYFFLANLSLVDLCLPSATVPKMLLNIQTQTQTISYPGCLAQMYFCMMFANMDNFLLTVMAYDRYVAICHP---------LHYSTIMALRLCASLVAAPWVIAILNPLLHTLMMAHLHFCSDNVIHHFFCDINSLLPLSCSDTSLNQLSVLATVGLIFVVPSVCILVSYILIVSAV-MKVPSAQGKLKAFSTCGSHLALVI--LFYGAITGVYMSP--LSNHSTEK---DSAASVIFMVVAPVLNPFIYSLRNNELKGTLKKTLSRPGAVAHACNPSTLGGRGGWIMRSGDRDHPG------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH92-1", "uniprot_id": "OR1S1_HUMAN", "id": "Q8NH92-1", "name": "Olfactory receptor 1S1", "aln": "------------------MKTFS-----SFLQIGRNMHQ---GNQTTITEFILLGFFKQDEHQNLLFVLFLGMYLVTVIGNGLIIVAISLDTYLHTPMYLFLANLSFADISSISNSVPKMLVNIQTKSQSISYESCITQMYFSIVFVVIDNLLLGTMAYDHFVAICHP---------LNYTILMRPRFGILLTVISWFLSNIIALTHTLLLIQLLFCNHNTLPHFFCDLAPLLKLSCSDTLINELVLFIVGLSVIIFPFTLSFFSYVCIIRAV-LRVSSTQGKWKAFSTCGSHLTVVL--LFYGTIVGVYFFP--SSTHPED---TDKIGAVLFTVVTPMINPFIYSLRNKDMKGALRKLINRKISSL-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGQ3-1", "uniprot_id": "OR1S2_HUMAN", "id": "Q8NGQ3-1", "name": "Olfactory receptor 1S2", "aln": "------------------MKTLC-----SFLQISRNMHQ---ENQTTITEFILLGLSNQAEHQNLLFVLFLSMYVVTVVGNGLIIVAISLDIYLHTPMYLFLAYLSFADISSISNSVPKMLVNIQTNSQSISYESCITQMYFSIVFVVTDNLLLGTMAFDHFVAICHP---------LNYTTFMRARFGTLLTVISWFLSNIIALTHTLLLIQLLFCDHNTLPHFFCDLAPLLKLSCSDTMINELVLFIVGLSVIIFPFVLIFFSYVCIIRAV-LGVSSTQGKWKAFSTCGSHLTIAL--LFYGTTVGVYFFP--SSTHPED---TDKIGAVLFTVVTPMMNPFIYSLRNKDMKGALRKLINRKISSL-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1LV45-1", "uniprot_id": "F1LV45_RAT", "id": "F1LV45-1", "name": "Olfactory receptor", "aln": "----------------------------------RNMSQ---GNQTTISEFILLGLSNQAEKQKFIFVIFLSMYLVTVLGNSLIILVIGLDVNLHTPMYLFLANLSFADISSSSTSVPKMLMNIQTKSQYISYEGCFTQMYFSIVFVVIDNFLLGVMAYDRYVAICHP---------LTYTSIMHSTFCLLLTVCPWALSNIVALTHTLLANQLIFCNDNTIQHFFCDLAPLLKLSCSDAMINNIVKFIVGLSVITFPFALILFSYVCIIRDV-LRISSMEGKWKAFSTCGSHLTVVF--LFYGTIIGVYFFP--LSTHPED---TDKIGAVLFTVVTPMLNPFIYSLRNKDMKGAFKKLINKSHFFLLMS----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEU7-1", "uniprot_id": "Q8VEU7_MOUSE", "id": "Q8VEU7-1", "name": "Olfactory receptor", "aln": "------------------MLPFNDEDEFSLFRYSRTMHQ---GNQTAISGFILLGLTVGSEQQLLLFTLFLCMYLVTMVGNSLIILAIISDTHLYSPMYFFLANLSFTDICFTTTTVPKILADIQSQNPTISFVGCFTQMYFFMFLVDLDNFLLAAMAYDRYIAICHP---------LHYAALLNPKRCALLVVVPWVISNLVSVLHLSLLSRLPFCDQRVIPHFFCDLEPVLRLACSDTQINNLLILIVGGTVIFVPFVFILVSYALIGTAV-LNVPSVKGKWKTFSTCGSHLSAVS--LFYGSIVGVYFLP--ASSYSAE---RDKVAAIMYTVVTPMMNPFIYSLRNKDMKRALRRLLSQKSLICSW-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30953-1", "uniprot_id": "OR1E1_HUMAN", "id": "P30953-1", "name": "Olfactory receptor 1E1", "aln": "------------------------------------MMG---QNQTSISDFLLLGLPIQPEQQNLCYALFLAMYLTTLLGNLLIIVLIRLDSHLHTPMYLFLSNLSFSDLCFSSVTIPKLLQNMQNQDPSIPYADCLTQMYFFLLFGDLESFLLVAMAYDRYVAICFP---------LHYTAIMSPMLCLALVALSWVLTTFHAMLHTLLMARLCFCADNVIPHFFCDMSALLKLAFSDTRVNEWVIFIMGGLILVIPFLLILGSYARIVSSI-LKVPSSKGICKAFSTCGSHLSVVS--LFYGTVIGLYLCS--SANSSTL---KDTVMAMMYTVVTPMLNPFIYSLRNRDMKGALSRVIHQKKTFFSL-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47887-1", "uniprot_id": "OR1E2_HUMAN", "id": "P47887-1", "name": "Olfactory receptor 1E2", "aln": "------------------------------------MMG---QNQTSISDFLLLGLPIQPEQQNLCYALFLAMYLTTLLGNLLIIVLIRLDSHLHTPVYLFLSNLSFSDLCFSSVTMPKLLQNMQNQDPSIPYADCLTQMYFFLYFSDLESFLLVAMAYDRYVAICFPMHYTAICFLLHYTAIMSPMLCLSVVALSWVLTTFHAMLHTLLMARLCFCADNVIPHFFCDMSALLKLACSDTRVNEWVIFIMGGLILVIPFLLILGSYARIVSSI-LKVPSSKGICKAFSTCGSHLSVVS--LFYGTVIGLYLCP--SANSSTL---KDTVMAMMYTVVTPMLTPFIYSLRNRDMKGALERVICKRKNPFLL-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8WZA6-1", "uniprot_id": "OR1E3_HUMAN", "id": "Q8WZA6-1", "name": "Olfactory receptor 1E3", "aln": "------------------------------------MMK---KNQTMISEFLLLGLPIQPEQQNLFYALFLAVYLTTLLGNLLVIVLIRLDSHLHMPMYLCLSNLSFSDLCFSSVTMPKLLQNMQSQNPSIPFADCLAQMYFHLFYGVLESFLLVVMAYHCYVAICFP---------LHYTTIMSPKCCLGLLTLSWLLTTAHATLHTLLMARLSFCAENVIPHFFCDTSTLLKLACSNTQVNGWVMFFMGGLILVIPFLLLIMSCARIVSTI-LRVPSTGGIQKAFSTCGPHLSVVS--LFYGTIIGLYLCP--LTNHNTV---KDTVMAVMYTGVTHMLNPFIYSLRNRDMRGNPGQSLQHKENFFVFKIVIVGILPLLNLVGVVKLIMKYHSKSVA------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZVZ1-1", "uniprot_id": "D3ZVZ1_RAT", "id": "D3ZVZ1-1", "name": "Olfactory receptor", "aln": "------------------------------------MTQ---DNESTVSDFNLLGLPIRAEDQGVYSVLFLIMYLTTVLGNLLIILLIRLDPHLHTPMYFFLSHLALTDISFSSVTAPKMLMNMLTHSQSISYAGCVSQVYFYIAFSDLDSFLLTSMAYDRYVAICHP---------LHYNTIMSQNLCVLLLVMSWALSSANALVHTLLLARLSHFRNNTISHYFCELSALLKLSSSDTTINKMVILPLGTVVITLPFVLILVSYGCIGVTI-LKIPSINGIYKTLSTCGSHLCVVS--LYYGAIIGLYFVP--SSNNTND---QDAIVAVIYTVVTPMLNPFIYSLRNRDMKGALKNILSRR-LCSQ------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LIW9-1", "uniprot_id": "A0ABK0LIW9_RAT", "id": "A0ABK0LIW9-1", "name": "Olfactory receptor", "aln": "------------------------------------MME---TNQSTVSEFILLGLPIQPEDQAVYSVLFLAMYMTTVLGNLLIILLIRLDSHLHTPMYFFLSHLAFTDISFSSVTAPKMLMNMLTHSQSISYAGCVSQIYFFLLFGCIDNFLLTSMAYDRYVAICHP---------LHYTTVMSQSLCVLLVMISWVFSSTNGLVHTLLFARLSHFKDNTVHHFFCDLSALLKLSISDTTINELVILTLAVVVITVPFICILISYGHIGATI-LRTPTIQGICKALSTCGSHLCVVF--LYYGAIIGLYFFP--SSNNTNA---KDVIASVLYTVVTPMLNPFIYSLRNRDMKGALKNTLSRR-LCSH------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGS3-1", "uniprot_id": "OR1J1_HUMAN", "id": "Q8NGS3-1", "name": "Olfactory receptor 1J1", "aln": "------------------------------------MSP---ENQSSVSEFLLLGLPIRPEQQAVFFALFLGMYLTTVLGNLLIMLLIQLDSHLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQHLAVFYKGCISQTYFFIFFADLDSFLITSMAYDRYVAICHP---------LHYATIMTQSQCVMLVAGSWVIACACALLHTLLLAQLSFCADHIIPHYFCDLGALLKLSCSDTSLNQLAIFTAALTAIMLPFLCILVSYGHIGVTI-LQIPSTKGICKALSTCGSHLSVVT--IYYRTIIGLYFLP--PSSNTND---KNIIASVIYTAVTPMLNPFIYSLRNKDIKGALRKLLSRSGAVAHACNLNTLGG---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3Z9I7-1", "uniprot_id": "D3Z9I7_RAT", "id": "D3Z9I7-1", "name": "Olfactory receptor", "aln": "------------------------------------MRL---KNHSSVSEFLLLGLPIRAEQSGIFFSMFLAMYLTTVLGNLLIILLIRLDSHLHTPMYFFLSHLAFTDISFSSVTVPKMLTKVPNQNIPITYEGCVSQTYFFIFFADLDSFLITSMAYDRYMAICHP---------LNYTTIMNQSRCATLVAISWIIASACALLHTLLLDQLSFCADHTIPHFFCDLGALLKLSCSDTSLNQLVIFTAGLAAIMLPFLCILISYGHIGFTI-LQVPSTKGICKALSTCGSHLSVVA--LYYGSIIGLYFLP--PSNSTIN---NNIVASVMYTVVTPMLNPFIYSLRNKDMKGALRKLLSKKVEFSN------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGS2-1", "uniprot_id": "OR1J2_HUMAN", "id": "Q8NGS2-1", "name": "Olfactory receptor 1J2", "aln": "------------------------------------MSP---ENQSSVSEFLLLGLPIRPEQQAVFFTLFLGMYLTTVLGNLLIMLLIQLDSHLHTPMYFFLSHLALTDISFSSVTVPKMLMDMRTKYKSILYEECISQMYFFIFFTDLDSFLITSMAYDRYVAICHP---------LHYTVIMREELCVFLVAVSWILSCASSLSHTLLLTRLSFCAANTIPHVFCDLAALLKLSCSDIFLNELVMFTVGVVVITLPFMCILVSYGYIGATI-LRVPSTKGIHKALSTCGSHLSVVS--LYYGSIFGQYLFP--TVSSSID---KDVIVALMYTVVTPMLNPFIYSLRNRDMKEALGKLFSRATFFSW------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGS1-1", "uniprot_id": "OR1J4_HUMAN", "id": "Q8NGS1-1", "name": "Olfactory receptor 1J4", "aln": "------------------------------------MKR---ENQSSVSEFLLLDLPIWPEQQAVFFTLFLGMYLITVLGNLLIILLIRLDSHLHTPMFFFLSHLALTDISLSSVTVPKMLLSMQTQDQSILYAGCVTQMYFFIFFTDLDNFLLTSMAYDRYVAICHP---------LRYTTIMKEGLCNLLVTVSWILSCTNALSHTLLLAQLSFCADNTIPHFFCDLVALLKLSCSDISLNELVIFTVGQAVITLPLICILISYGHIGVTI-LKAPSTKGIFKALSTCGSHLSVVS--LYYGTIIGLYFLP--SSSASSD---KDVIASVMYTVITPLLNPFIYSLRNRDIKGALERLFNRATVLSQ------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VFM8-1", "uniprot_id": "Q8VFM8_MOUSE", "id": "Q8VFM8-1", "name": "Olfactory receptor", "aln": "------------------------------------MES---KNQTDVSEFFLMGITDDIALKPLIFSMFTSMYLITILGNLLIILTVCSDSHLQTPMYIFLSNLSFNDICLSTTIIPKTLVNIHAQDQSITYTSCLTQICFTLLFCSFESCLLSVMAYDRYVAICHP---------LNYTTIMNPQTCGLLILLSLIISLVNSGLLGLMVLRLSFCTNLEIPLFFCELAQVIKLACSDTLVNYILIYLATIILNGIPISGIIFSYTQIASSV-LRMSSVKGKYKAISTCGSHLSVVS--LFYGTALGVYISS--SFTTSVT---NTAFAYVMCTLVPQMLNPFIYSLRNRDMEVALRKHINRAMCLL-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGR2-1", "uniprot_id": "OR1L6_HUMAN", "id": "Q8NGR2-1", "name": "Olfactory receptor 1L6", "aln": "MSYFYRLKLMKEAVLVKLPFTSLPLLLQTLSRKSRDMEIK--NYSSSTSGFILLGLSSNPQLQKPLFAIFLIMYLLAAVGNVLIIPAIYSDPRLHTPMYFFLSNLSFMDICFTTVIVPKMLVNFLSETKVISYVGCLAQMYFFMAFGNTDSYLLASMAIDRLVAICNP---------LHYDVVMKPRHCLLMLLGSCSISHLHSLFRVLLMSRLSFCASHIIKHFFCDTQPVLKLSCSDTSSSQMVVMTETLAVIVTPFLCIIFSYLRIMVTV-LRIPSAAGKWKAFSTCGSHLTAVA--LFYGSIIYVYFRP--LSMYSVV---RDRVATVMYTVVTPMLNPFIYSLRNKDMKRGLKKLQDRIYR---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TRY4-1", "uniprot_id": "Q7TRY4_MOUSE", "id": "Q7TRY4-1", "name": "Olfactory receptor", "aln": "-------------------------------------MLR--ENQSHMTEFLLLGLTSNPKQQVWLFASFLAMYLVNVIGNSVIIASIQRDARLHTPMYFFLSNLSLVDICFTTVIVPQMLVNLLTQRKTILFAQCLTQMYFFVAFGITDSFLLAAMAIDRYVAICNP---------LHYNTVMSPRRCRLLVVASWAVSHLHSLTHTILMGRLSFCGPNVIHHFFCDVQPLLTLSCSDTSINELLAFTEGSVVIMSPFIFIVVSYIYITRTV-LRVPSGEGRYKVFSTCGSHLTVVA--LFYGTIISVYIRP--SSTYSVT---KDRVVTVIYTVVTPMLNPFIYSLRNKDMKQALRKLAKRTE----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A4S6-1", "uniprot_id": "D4A4S6_RAT", "id": "D4A4S6-1", "name": "", "aln": "------------------------------------MAV---TNLTYRPQFQLLGLMDGADTHPLLFLLFLSIYLLNALGNLSMVVLVRSDGALCSPMYYFLGHLSLVDVCFTTVTVPRLLVTLLHPGQAMSFQDCFAQMYFFVALGITESYLLAAMSYDRVVAVCRP---------LHYGVVMTPWRCFVLVAASWTVAHLHSLLHTLLISALSYPRSAPVHHFFCDMTVMLSLATSDTSTAETAIFSEGLAVVLTPLILVSLSYARILVAV-LGMQTTGGRHRVFSTCGAHLVVVS--LFFGSVLSVYFRP--SFGYSAR---YDRMASVVYAVVTPTLNPFIYSLRNKEVKGALKRGFRWRAAAQDE-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VFY0-1", "uniprot_id": "Q8VFY0_MOUSE", "id": "Q8VFY0-1", "name": "", "aln": "------------------------------------MAV---TNLTYKPQFQLLGLMDGTDPHPLLFLLFLSIYLLNALGNLSMVVLVRSDGALCSPMYYFLGHLSLVDVCFTTVTVPRLLATLLHPGQAISFQACFAQMYFFVALGITESYLLAAMSYDRAVAVCRP---------LHYGAVMTPWRCFLLVAASWAVAHLHSLLHTLLISALTYPPSAPVRHFFCDMTVMLSLATSDTSAAETAIFSEGLTVVLTPLLLVSLSYARILVAV-LGIRTTGGRHRVFSTCGAHLVVVS--LFFGSVLSVYFRP--SSAYSAR---YDRMASVVYAVVTPTLNPFIYSLRNKEVKSALKRGFRWRAAPQDE-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A286YEU6-1", "uniprot_id": "OR1R1_HUMAN", "id": "A0A286YEU6-1", "name": "Olfactory receptor 1R1", "aln": "------------------------------------MAP---TNLTSAPVFLLLGLVDGTDAHPLLFLLCLGIYLLNALSNLSMVALVRSDGALRSPMYYFLGHLSLVDVCFTTVTVPRLLAGLLHPGQAISFQACFAEMYFFVALGITESYLLAAMSYDRPTAACRP---------LRYGALVTPWRCASLVRASWAVTHLHSLLHTLLLSALSYPYPTPVRPFFCDMTVMLSLATSDTSAAETAIFSEGLAVVLAPLLLVFLFLR--AHPG-RGARLAGGRRRAFSTCGAHLVAVAVALFFGSVLSVYFPP--SSAYSAR---YDRLASVVYAVITPTLNPFINSLRNKEVKGALKRGLRWRAAPQEA-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LNM5-1", "uniprot_id": "A0ABK0LNM5_RAT", "id": "A0ABK0LNM5-1", "name": "", "aln": "------------------------------------MAP---VNQSVVTMFILQNFVDDPWIQDVLFCLFFALFMMAIAGNGLIIMTIYSSANLHTPMYFFLVNLSLMDVICTVTVLPKVLQSLVAEN-AISYGGCLTQMFVFSWVLGSELLLFSAMAYDRYLAICRP---------LHYGTLMNGRACVALATFVWFTGALNSLVLTCLVLPLSFCGPNLITHFFCEIPSVLMLSCSSTFINDIMTVITDMFLTGLNFLLTMTSYVFIIASI-LRIRSAEGKKRAFSTCSAHLVVVT--LYYSTVLYTYVRP--ALGTAGL---LDKAVAVLYTTVTPSLNPLIYTLRNKEFKTSFKKLLFPH-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6B0Y0-1", "uniprot_id": "A0A8I6B0Y0_RAT", "id": "A0A8I6B0Y0-1", "name": "", "aln": "------------------------------------MAP---INQSVVTMFFLQNFVDDPWIQNVLFCFFFALFVAAIAGNGLIITVIHSSANLHTPMYFFLVNLSLMDVICTVTVLPKVLQSLVAEN-AISYGGCLTQMFVFSWVLGSELLLFSAMAYDRYLAICRP---------LHYGTLMSGRVCIALATFVWFTGALNSLVLTCLVLPLSFCGPNLITHFFCEIPSVLMLSCSPTFINDIMTVIADMFLTGLNFLLTMTSYGFIIASI-LRIRSAEGKKRAFSTCSAHLVVVT--LYYSTVLYTYVRP--ALGTSGL---LDKVIAVLYTTVTPSLNPLIYTLRNKEFKTSFKKLLFPN-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2K0L2-1", "uniprot_id": "A0A0G2K0L2_RAT", "id": "A0A0G2K0L2-1", "name": "", "aln": "------------------------------------------MNGTLVTEFLILGFSEMPHLRVP-LLSFLCLYMAAISGNLLIMVTVSASPALHTPMYFFLVNLAVVDILCTSTILPKLLDIMVGGR-TISYGGCMAQLFFFTWSMGAELLLFSAMAYDRFVAICCP---------LHYSTWMGPRVCAFLAGLVWSISLTNTSVNTSLVLHLPFCSSNVIEHFFCEIPPLLKLSCAPTQLNEVMAFAADVFLAVGNFSVIILSYGFIVTSI-LKIRSTEGKQRAFSTCSAHLFVVT--MYYSTIIYTYIRP--ASSYSLN---KDKVVSIIYTSVAPTLNPLIYTLRNKDVKVALRKLLSSC-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TRT9-1", "uniprot_id": "Q7TRT9_MOUSE", "id": "Q7TRT9-1", "name": "", "aln": "--------------------------------------M---MNGTLVTEFLILGFSEMPHLRVPLLFSFLCLYMAAISGNLLIMVTISASPALHTPMYFFLVNLAIVDILCTSTILPKLLDSMMTGR-TISYGGCMAQLFFFTWSLGAELLLFSAMAYDRFVAICCP---------LHYSAWMGPRVCAFLAGIVWTISLTNTSVHTGLMLRLPFCSSNVIEHFFCEIPPLLKLSCAPTQLNEAMAFAADVFLAVGNFSVTILSYGFIVASI-LKIRSAEGKRRAFSTCSAHLIVVT--MYYSTVIYTYIRP--SSSYSLN---KDKVVSIIYTSVAPTLNPLIYTLRNKDVKVALRRLLSCC-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGL2-1", "uniprot_id": "Q8VGL2_MOUSE", "id": "Q8VGL2-1", "name": "", "aln": "------------------------------------------MNGTLVTEFLILGFSDMPHLRILLFLSFLCLYMAAVSGNLLIMVTISASPTLHTPMYFFLVNLAVVDILCTSTILPKLLDTMVGGR-TISYGGCMAQLFFFTWSLGVELLLFSAMAYDRFVAICCP---------LHYSTWMGPRVCAFLAGIVWAISLTNTSINSSLVLRLPFCSSNVVEHFFCEIPPLLKLSCAPTQLNEAMAFAADVFLAVGNFSVIILSYGFIVASI-LKIRSAEGKQRAFSTCSAHLIVVT--MYYSTVIYTYIRP--SSSYSLN---KDKVVSIIYTSVAPTLNPLIYTLRNKDVKVALRRLFSCC-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TS01-1", "uniprot_id": "Q7TS01_MOUSE", "id": "Q7TS01-1", "name": "", "aln": "--------------------------------------M---MNFSIVSEFMILGLTQKSELQGILFIVFLFIYLVALLGNMLIVVAIIYNTTLHTPMYILLLALAVVDIICTTSIIPKMLGTMLTSKNSISYGGCMSQLFFFTWSLGAEMVLFTTMAYDRYVAICFP---------LRYSTIMNHYTCVGLLSIVMAIAVTNSWVHTGLILRLTFCGPNIIDHFFCEIPPLLALSCSPVRVNEVMVYVADITLAVGDFTLTCISYGFIIAAI-LRIRTTEGKKKAFSTCSSHLMVVS--LYYSPVIYTYIRP--ASSYTFD---KDKVVAALYTLVTPTLNPIVYSFRNKEMQSGIKKVFAFLKG---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGZ3-1", "uniprot_id": "O13G1_HUMAN", "id": "Q8NGZ3-1", "name": "Olfactory receptor 13G1", "aln": "------------------------------------------MNHSVVTEFIILGLTKKPELQGIIFLFFLIVYLVAFLGNMLIIIAKIYNNTLHTPMYVFLLTLAVVDIICTTSIIPKMLGTMLTSENTISYAGCMSQLFLFTWSLGAEMVLFTTMAYDRYVAICFP---------LHYSTIMNHHMCVALLSMVMAIAVTNSWVHTALIMRLTFCGPNTIDHFFCEIPPLLALSCSPVRINEVMVYVADITLAIGDFILTCISYGFIIVAI-LRIRTVEGKRKAFSTCSSHLTVVT--LYYSPVIYTYIRP--ASSYTFE---RDKVVAALYTLVTPTLNPMVYSFQNREMQAGIRKVFAFLKH---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O42169-1", "uniprot_id": "O42169_DANRE", "id": "O42169-1", "name": "", "aln": "-------------------------------MNFLNESFYQNISFVHPQYFYIIGLSGTP-YSSYFYVFLFITYFITLFGNSVVLLIIALDRSLHSPKYIGVFNLALADIGETNALIPNMVKTFLFDSQYISYNACLANMFFVFLFSSIQSFALLVLAFDRFVAICLP---------LRYHALVNNTTMLLAFAAVWAFNSFVVALMVSLITRLSFCQSNMIQSYFCDHGPVYRIACNDFSINKFMAFLITGLYLVIPLFLIVLSYLGIFLAL-TKITTFEGRIKALKTCVSHLLLVG--TLFLPLFCTYFAQLLLSLSPNAR----VICTSLAYTIPPMLNPIIYVLNTAEIKDIIWKVFKNKSVAVESISK--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : .* :. * : : :: : . : : *. : : :: . * * : : : : : :: :.:.** *: * . ..*:: :.. :. . ", "identical_positions": 10, "similar_positions": 44, "identity": "2.43%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010308-17", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TQQ0-1", "uniprot_id": "OR4E2_MOUSE", "id": "Q7TQQ0-1", "name": "Olfactory receptor 4E2", "aln": "---------------------------------------MGALNQT-RVTEFIFLGLTDNWVLEILFFVPFTVTYMLTLLGNFLIVVTIVFTPRLHNPMYFFLSNLSFIDICHSSVTVPKMLEGLLLERKTISFDNCIAQLFFLHLFACSEIFLLTIMAYDRYVAICIP---------LHYSNVMNMKVCVQLVFALWLGGTIHSLVQTFLTIRLPYCGPNIIDSYFCDVPPVIKLACTDTYLTGILIVSNSGTISLVCFLALVTS--YTVILFSLRKQSAEGRRKALSTCSAHFMVVA--LFFGPCIFLYTRP----DSSFSIDKVVSVFYTVVTPLLNPLIYTLRNEEVKTAMKHLRQRRICS--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ADC0-1", "uniprot_id": "D4ADC0_RAT", "id": "D4ADC0-1", "name": "Olfactory receptor", "aln": "---------------------------------------MGALNQT-RVTEFVFLGLTDNWVLEILFFIPFTVTYVLTLLGNVLIVVTIVFTPRLHNPMYFFLSNLSFIDICHSSVTVPKMLEGLLLVRKTISFDNCIAQLFFLHLFACAEIFLLTIMAYDRYVAICIP---------LHYPNVMNMKVCVQLVFALWLGGTVHSLVQTFLTIRLPYCGPNTIDSYFCDVPPVIKLACTDTYLTGILIVSNSGTISLVCFLALVTS--YTVILFSLRKQSAEGRRKALSTCSAHFMVVA--LFFGPCIFIYTWP----DTSFSIDKVVSVFYTVVTPLLNPLIYTLRNEEVKTSMKHLRQRRICS--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGC2-1", "uniprot_id": "OR4E2_HUMAN", "id": "Q8NGC2-1", "name": "Olfactory receptor 4E2", "aln": "---------------------------------------MDSLNQT-RVTEFVFLGLTDNRVLEMLFFMAFSAIYMLTLSGNILIIIATVFTPSLHTPMYFFLSNLSFIDICHSSVTVPKMLEGLLLERKTISFDNCITQLFFLHLFACAEIFLLIIVAYDRYVAICTP---------LHYPNVMNMRVCIQLVFALWLGGTVHSLGQTFLTIRLPYCGPNIIDSYFCDVPLVIKLACTDTYLTGILIVTNSGTISLSCFLAVVTS--YMVILVSLRKHSAEGRQKALSTCSAHFMVVA--LFFGPCIFIYTRP----DTSFSIDKVVSVFYTVVTPLLNPFIYTLRNEEVKSAMKQLRQRQVFFTKSYT---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R0K4-1", "uniprot_id": "Q9R0K4_MOUSE", "id": "Q9R0K4-1", "name": "Olfactory receptor", "aln": "------------------------------------MEKAVLINETSVMS-FRLTGLSTNPLVQMAVFFIFLIFYVLTLVGNILIVITIIYDRRLHTPMYFFLSNLSFIDVCHSTVTVPKMLSDTFSEEKLISFDACVVQMFFLHLFACTEIFLLTVMAYDRYVAICKP---------LQYMTIMNWKVCMMLAAALWTGGTIHSISLTSLTIKLPYCGPDEIDNFFCDVPQVIKLACTDTHIIEILIVSNSGLISVVCFVVLVVS--YAVILVSLRQQISDGKRKALSTCAAHLTVVT--LFLGHCIFIYSRP----STSLPEDKVVSVFFTAVTPLLNPIIYTLRNEDMKSALNKLIKRREK---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C645-1", "uniprot_id": "OR4E1_HUMAN", "id": "P0C645-1", "name": "Olfactory receptor 4E1", "aln": "------------------------------------MEEAILLNQTSLVTYFRLRGLSVNHKARIAMFSMFLIFYVLTLIGNVLIVITIIYDHRLHTPMYFFLSNLSFIDVCHSTVTVPKMLRDVWSEEKLISFDACVTQMFFLHLFACTEIFLLTVMAYDRYVAICKP---------LQYMIVMNWKVCVLLAVALWTGGTIHSIALTSLTIKLPYCGPDEIDNFFCDVPQVIKLACIDTHVIEILIVSNSGLISVVCFVVLVVS--YAVILVSLRQQISKGKRKALSTCAAHLTVVT--LFLGHCIFIYSRP----STSLPEDKVVSVFFTAVTPLLNPIIYTLRNEEMKSALNKLVGRKERKEEK-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2I3BQG5-1", "uniprot_id": "A0A2I3BQG5_MOUSE", "id": "A0A2I3BQG5-1", "name": "Olfactory receptor", "aln": "---------------------------MSAPTSVYQGSNSVLLNQT-LVTEFLLLGVTDIQELNPILFVTVLAMYFVNVAGNGAILLIVISDPRLHSPMYFFLGNLACLDICFSTVTVPKILDNFFSTSKAISFLGCITQLYFFHLLGSTEALLLAVMAFDRFVAICRP---------LHYPSIMNGQVCIQVAISIWAIPFVHALVHSILTSQLNFCGSNQIHHFFCDVKPLLELACGNTELNRWLLNTFTGTFAIGLFFLTFLSYFYIITYLFLKTRSCSMLHKALSTCASHFMVVM--IFYAPVLFIYINP--DSGSSLEKDRIIAVMYTVVTPALNPLIYTLRNKEVRGALNRKLRILL----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2I3BRX0-1", "uniprot_id": "A0A2I3BRX0_MOUSE", "id": "A0A2I3BRX0-1", "name": "Olfactory receptor", "aln": "---------------------------MSAPTSVSQEGNSVLLNHT-LVTEFLLLGVTDIQELNPILFVTVLAMYFVNVAGNGAILMIVISDPRLHLPMYFFLGNLACLDICFSTVTVPKMLENFFSTSKAISFLGCITQLHFFHFLGSTEALLLTVMAFDRFVAICRP---------LHYPAIMNSQVCIQVAISIWAIPFLHALVHSILTSQLNFCGSNHIHHFFCDVKPLLELACGNTELNRWLLNTLTGTVAIGLFFLTFLSYFYIVTYLFLKTRSCSMLHKALSTCASHFMVVM--IFYAPVLFIYINP--DSGSSLEKDRIIAVMYTVVTPALNPLIYTLRNKEVRGALNRKIRILL----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58182-1", "uniprot_id": "O12D2_HUMAN", "id": "P58182-1", "name": "Olfactory receptor 12D2", "aln": "-----------------------------------------MLNTT-SVTEFLLLGVTDIQELQPFLFVVFLTIYFISVTGNGAVLMIVISDPRLHSLMYFFLGNLSYLDICYSTVTLPKMLQNFLSTHKAISFLGCISQLHFFHSLGSTESMLFAVMAFDLSVAICKP---------LRYTVIMNPQLCTQMAITIWVIGFFHALLHSVMTSRLNFCGSNRIHHFLCDIKPLLKLACGNTELNQWLLSTVTGTIAMGPFFLTLLSYFYIITYLFFKTRSCSMLCKALSTCASHFMVVI--LFYAPVLFTYIHP--ALESFMDQDRIVAIMYTVVTPVLNPLIYTLRNKEVKGALGRVIRRL-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VG96-1", "uniprot_id": "Q8VG96_MOUSE", "id": "Q8VG96-1", "name": "Olfactory receptor", "aln": "-----------------------------------------MENST-SVDEFLLLGLTSVQKLQPIIFVMFLTIYLLNLVGNGVILMIVTLERRLHSPMYFFLGNLSCLDICYSSVTLPKVLINLLSRRRAISFLGCITQLYFFHFLGSTEAILLAVMAFDRFVAICSP---------LRYTAIMNPQLCILLAATAWFTSFFYALLHSVMTAHLNFCHSHKLSHFFCDVKPLLEVACGNTVLNQWLLSVVTGSISMGAFLLILLSYFYIIAFLLFKNRSCRMLKKALSTCTSHFMVVC--LFYGPVGFTYIRPATASASSMSEDRVVAIIYSAVTPVLNPLIYTLRNKEVMLALKKNFGKKLFKGN------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGF7-1", "uniprot_id": "O12D3_HUMAN", "id": "Q9UGF7-1", "name": "Olfactory receptor 12D3", "aln": "-----------------------------------------MENVT-TMNEFLLLGLTGVQELQPFFFGIFLIIYLINLIGNGSILVMVVLEPQLHSPMYFFLGNLSCLDISYSSVTLPKLLVNLVCSRRAISFLGCITQLHFFHFLGSTEAILLAIMAFDRFVAICNP---------LRYTVIMNPQVCILLAAAAWLISFFYALMHSVMTAHLSFCGSQKLNHFFYDVKPLLELACSDTLLNQWLLSIVTGSISMGAFFLTLLSCFYVIGFLLFKNRSCRILHKALSTCASHFMVVC--LFYGPVGFTYIRP--ASATSMIQDRIMAIMYSAVTPVLNPLIYTLRNKEVMMALKKIFGRKLFKDWQQHH--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VGG9-1", "uniprot_id": "Q8VGG9_MOUSE", "id": "Q8VGG9-1", "name": "Olfactory receptor", "aln": "------------------------------------MDG---DNQT-IVTEFILLGLTRQSEKEEVVFGLFLWMYLVTISGNLLIILAISCDPHLHTPMYFFLANLSSVDISAPSVIVPKALVNHMLGSKSISYTGCMTQIYFFITFSNMDGFLLSVMAYDRYVAICHP---------LHYTMMMRPRLCVLLVAISWAITNLHALLHTLLMVRLTFCSHNAVHHFFCDPYPILKLSCSDTFINDLMVFTIGGLVFMTPFTCIIVSYAYIFSKV-LKLKSAHGIRKALSTCGSHLTVVS--LFYGAILGIYMHPSSTYTV--Q-DTVATVIFTVVTPMVNPFIYSLRNRDIKGALRKIILRS-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGH1-1", "uniprot_id": "Q8VGH1_MOUSE", "id": "Q8VGH1-1", "name": "Olfactory receptor", "aln": "------------------------------------MDG---DNET-MVAEFLLLGLSGKSEQEEVVFGMFLGMYLVTISGNLLIILAISCDPHLHTPMYFFLANLSSVDICFSSVTVPKALVNHVLGSKSISYTECMIQIYFFITFINMDGFLLSVMAYDRYVAICHP---------LHYTMMMRSRLCVLLVAISWVITNLHALLHTLLMVRLTFCSHNAVHHFFCDPYPILKLSCSDTFINDLMVFTVGGVIFLTPFSCIVVSYVYIFSKV-LKIPSARGIRKALSTCGSHLTVVS--LFYGAILGVYMRPSSSYSL--Q-DTVATVIFTVVTPLVNPFIYSLRNQDMKGALRKIMLRS-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NHA8-1", "uniprot_id": "OR1FC_HUMAN", "id": "Q8NHA8-1", "name": "Putative olfactory receptor 1F12P", "aln": "------------------------------------MEG---KNQT-NISEFLLLGFSSWQQQQVLLFALFLCLYLTGLFGNLLILLAIGSDHCLHTPMYFFLANLSLVDLCLPSATVPKMLLNIQTQTQTISYPGCLAQMYFCMMFANMDNFLLTVMAYDRYVAICHP---------LHYSTIMALRLCASLVAAPWVIAILNPLLHTLMMAHLHFCSDNVIHHFFCDINSLLPLSCSDTSLNQLSVLATVGLIFVVPSVCILVSYILIVSAV-MKVPSAQGKLKAFSTCGSHLALVI--LFYGAITGVYMSPLSNHST--EKDSAASVIFMVVAPVLNPFIYSLRNNELKGTLKKTLSRPGAVAHACNPSTLGGRGGWIMRSGDRDHPG------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P30953-1", "uniprot_id": "OR1E1_HUMAN", "id": "P30953-1", "name": "Olfactory receptor 1E1", "aln": "------------------------------------MMG---QNQT-SISDFLLLGLPIQPEQQNLCYALFLAMYLTTLLGNLLIIVLIRLDSHLHTPMYLFLSNLSFSDLCFSSVTIPKLLQNMQNQDPSIPYADCLTQMYFFLLFGDLESFLLVAMAYDRYVAICFP---------LHYTAIMSPMLCLALVALSWVLTTFHAMLHTLLMARLCFCADNVIPHFFCDMSALLKLAFSDTRVNEWVIFIMGGLILVIPFLLILGSYARIVSSI-LKVPSSKGICKAFSTCGSHLSVVS--LFYGTVIGLYLCSSANSST--LKDTVMAMMYTVVTPMLNPFIYSLRNRDMKGALSRVIHQKKTFFSL-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47887-1", "uniprot_id": "OR1E2_HUMAN", "id": "P47887-1", "name": "Olfactory receptor 1E2", "aln": "------------------------------------MMG---QNQT-SISDFLLLGLPIQPEQQNLCYALFLAMYLTTLLGNLLIIVLIRLDSHLHTPVYLFLSNLSFSDLCFSSVTMPKLLQNMQNQDPSIPYADCLTQMYFFLYFSDLESFLLVAMAYDRYVAICFPMHYTAICFLLHYTAIMSPMLCLSVVALSWVLTTFHAMLHTLLMARLCFCADNVIPHFFCDMSALLKLACSDTRVNEWVIFIMGGLILVIPFLLILGSYARIVSSI-LKVPSSKGICKAFSTCGSHLSVVS--LFYGTVIGLYLCPSANSST--LKDTVMAMMYTVVTPMLTPFIYSLRNRDMKGALERVICKRKNPFLL-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8WZA6-1", "uniprot_id": "OR1E3_HUMAN", "id": "Q8WZA6-1", "name": "Olfactory receptor 1E3", "aln": "------------------------------------MMK---KNQT-MISEFLLLGLPIQPEQQNLFYALFLAVYLTTLLGNLLVIVLIRLDSHLHMPMYLCLSNLSFSDLCFSSVTMPKLLQNMQSQNPSIPFADCLAQMYFHLFYGVLESFLLVVMAYHCYVAICFP---------LHYTTIMSPKCCLGLLTLSWLLTTAHATLHTLLMARLSFCAENVIPHFFCDTSTLLKLACSNTQVNGWVMFFMGGLILVIPFLLLIMSCARIVSTI-LRVPSTGGIQKAFSTCGPHLSVVS--LFYGTIIGLYLCPLTNHNT--VKDTVMAVMYTGVTHMLNPFIYSLRNRDMRGNPGQSLQHKENFFVFKIVIVGILPLLNLVGVVKLIMKYHSKSVA------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZVZ1-1", "uniprot_id": "D3ZVZ1_RAT", "id": "D3ZVZ1-1", "name": "Olfactory receptor", "aln": "------------------------------------MTQ---DNES-TVSDFNLLGLPIRAEDQGVYSVLFLIMYLTTVLGNLLIILLIRLDPHLHTPMYFFLSHLALTDISFSSVTAPKMLMNMLTHSQSISYAGCVSQVYFYIAFSDLDSFLLTSMAYDRYVAICHP---------LHYNTIMSQNLCVLLLVMSWALSSANALVHTLLLARLSHFRNNTISHYFCELSALLKLSSSDTTINKMVILPLGTVVITLPFVLILVSYGCIGVTI-LKIPSINGIYKTLSTCGSHLCVVS--LYYGAIIGLYFVPSSNNTN--DQDAIVAVIYTVVTPMLNPFIYSLRNRDMKGALKNILSRR-LCSQ------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LIW9-1", "uniprot_id": "A0ABK0LIW9_RAT", "id": "A0ABK0LIW9-1", "name": "Olfactory receptor", "aln": "------------------------------------MME---TNQS-TVSEFILLGLPIQPEDQAVYSVLFLAMYMTTVLGNLLIILLIRLDSHLHTPMYFFLSHLAFTDISFSSVTAPKMLMNMLTHSQSISYAGCVSQIYFFLLFGCIDNFLLTSMAYDRYVAICHP---------LHYTTVMSQSLCVLLVMISWVFSSTNGLVHTLLFARLSHFKDNTVHHFFCDLSALLKLSISDTTINELVILTLAVVVITVPFICILISYGHIGATI-LRTPTIQGICKALSTCGSHLCVVF--LYYGAIIGLYFFPSSNNTN--AKDVIASVLYTVVTPMLNPFIYSLRNRDMKGALKNTLSRR-LCSH------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGS3-1", "uniprot_id": "OR1J1_HUMAN", "id": "Q8NGS3-1", "name": "Olfactory receptor 1J1", "aln": "------------------------------------MSP---ENQS-SVSEFLLLGLPIRPEQQAVFFALFLGMYLTTVLGNLLIMLLIQLDSHLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQHLAVFYKGCISQTYFFIFFADLDSFLITSMAYDRYVAICHP---------LHYATIMTQSQCVMLVAGSWVIACACALLHTLLLAQLSFCADHIIPHYFCDLGALLKLSCSDTSLNQLAIFTAALTAIMLPFLCILVSYGHIGVTI-LQIPSTKGICKALSTCGSHLSVVT--IYYRTIIGLYFLPPSSNTN--DKNIIASVIYTAVTPMLNPFIYSLRNKDIKGALRKLLSRSGAVAHACNLNTLGG---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3Z9I7-1", "uniprot_id": "D3Z9I7_RAT", "id": "D3Z9I7-1", "name": "Olfactory receptor", "aln": "------------------------------------MRL---KNHS-SVSEFLLLGLPIRAEQSGIFFSMFLAMYLTTVLGNLLIILLIRLDSHLHTPMYFFLSHLAFTDISFSSVTVPKMLTKVPNQNIPITYEGCVSQTYFFIFFADLDSFLITSMAYDRYMAICHP---------LNYTTIMNQSRCATLVAISWIIASACALLHTLLLDQLSFCADHTIPHFFCDLGALLKLSCSDTSLNQLVIFTAGLAAIMLPFLCILISYGHIGFTI-LQVPSTKGICKALSTCGSHLSVVA--LYYGSIIGLYFLPPSNSTI--NNNIVASVMYTVVTPMLNPFIYSLRNKDMKGALRKLLSKKVEFSN------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGS2-1", "uniprot_id": "OR1J2_HUMAN", "id": "Q8NGS2-1", "name": "Olfactory receptor 1J2", "aln": "------------------------------------MSP---ENQS-SVSEFLLLGLPIRPEQQAVFFTLFLGMYLTTVLGNLLIMLLIQLDSHLHTPMYFFLSHLALTDISFSSVTVPKMLMDMRTKYKSILYEECISQMYFFIFFTDLDSFLITSMAYDRYVAICHP---------LHYTVIMREELCVFLVAVSWILSCASSLSHTLLLTRLSFCAANTIPHVFCDLAALLKLSCSDIFLNELVMFTVGVVVITLPFMCILVSYGYIGATI-LRVPSTKGIHKALSTCGSHLSVVS--LYYGSIFGQYLFPTVSSSI--DKDVIVALMYTVVTPMLNPFIYSLRNRDMKEALGKLFSRATFFSW------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGS1-1", "uniprot_id": "OR1J4_HUMAN", "id": "Q8NGS1-1", "name": "Olfactory receptor 1J4", "aln": "------------------------------------MKR---ENQS-SVSEFLLLDLPIWPEQQAVFFTLFLGMYLITVLGNLLIILLIRLDSHLHTPMFFFLSHLALTDISLSSVTVPKMLLSMQTQDQSILYAGCVTQMYFFIFFTDLDNFLLTSMAYDRYVAICHP---------LRYTTIMKEGLCNLLVTVSWILSCTNALSHTLLLAQLSFCADNTIPHFFCDLVALLKLSCSDISLNELVIFTVGQAVITLPLICILISYGHIGVTI-LKAPSTKGIFKALSTCGSHLSVVS--LYYGTIIGLYFLPSSSASS--DKDVIASVMYTVITPLLNPFIYSLRNRDIKGALERLFNRATVLSQ------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VGK1-1", "uniprot_id": "Q8VGK1_MOUSE", "id": "Q8VGK1-1", "name": "Olfactory receptor", "aln": "------------------------------------ME-----NES-SVSEFFLQGISGFSEQQQLLYGLFLCMYLVTLTGNVLIILAIGSDPHLHTPMYFFLANLSFADMGLISSTVTKMLFNVQTRCHTISYTGCLTQMYFFLMFGDLDSFLLAVMAYDRYVAICHP---------LHYSTIMSARVCALMLALCWVLTNIVALTHTLLMARLSFCVVGEIAHFFCDITPVLKLSCSDTHVNELMVFALGGTVLMVPFVCIVISYIHIVFAI-LKVRTPGGGTKAFSTCSSHLCVVC--VFYGTLFSAYLCPPSVVST--EKDVAAAAMYTVVTPMLNPFIYSLRNKDMKGALKRLLCHRKFLS-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGK0-1", "uniprot_id": "Q8VGK0_MOUSE", "id": "Q8VGK0-1", "name": "Olfactory receptor", "aln": "------------------------------------ME-----NQS-SVSEFFLRGISGFPEQQQLLYGLFLCMYLVTLTGNVLIILAISCDPHLHTPMYFFLANLSFADMGLISSAVTKMLFNVQTQRHTISYTGCLTQMYLFMMFGDLDSFFLAVMAYDRYVAICHP---------LHYSTIMSARVCALMLALCWVLTNIVALTHTLLMTRLSFCVVGEIAHFFCDITSVMKLSCSDTHVNELVLSGFGGTVLMVPFVSIVISYVRIVFAV-LRVQTSGGSSKAFSTCSSHLCVVC--VFYGTLFSVYLFPSSGETT--EKDVVAAAMYTVVTPMLNPFIYSLRNKDMKGALKRLLCHRRKFSP------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGS0-1", "uniprot_id": "OR1N1_HUMAN", "id": "Q8NGS0-1", "name": "Olfactory receptor 1N1", "aln": "------------------------------------ME-----NQS-SISEFFLRGISAPPEQQQSLFGIFLCMYLVTLTGNLLIILAIGSDLHLHTPMYFFLANLSFVDMGLTSSTVTKMLVNIQTRHHTISYTGCLTQMYFFLMFGDLDSFFLAAMAYDRYVAICHP---------LCYSTVMRPQVCALMLALCWVLTNIVALTHTFLMARLSFCVTGEIAHFFCDITPVLKLSCSDTHINEMMVFVLGGTVLIVPFLCIVTSYIHIVPAI-LRVRTRGGVGKAFSTCSSHLCVVC--VFYGTLFSAYLCPPSIASE--EKDIAAAAMYTIVTPMLNPFIYSLRNKDMKGALKRLFSHRSIVSS------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VGJ8-1", "uniprot_id": "Q8VGJ8_MOUSE", "id": "Q8VGJ8-1", "name": "Olfactory receptor", "aln": "------------------------------------MGKISRVNQS-VASDFLLLGLSEQPGEQPLLFGIFLGMYLVTMVGNLLIIFVISSDAHLHTPMYFFLANLSLTDACFTSASVPKMLANIYTQSQTISYSGCLTQLYFLLMFGGLDNCLLAVMAYDRYVAICQP---------LHYSTAMSPQLCALMLCTCWVLTNCPALMHTLLLTRVAFCAHTAIPHFYCDPSALLKLACSDTHINELMIITMGLVFLAVPLMLIVFSYVCISWAV-LGIPSSGGRWKAFSTCGSHLTVVL--LFYGSLMGVYLLPPSTHST--ERESRAAVLYMIVIPMLNPFIYSLRNRDMKEAMGKLFGGGKTVFLL-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGR9-1", "uniprot_id": "OR1N2_HUMAN", "id": "Q8NGR9-1", "name": "Olfactory receptor 1N2", "aln": "------------------------------------MGKPGRVNQT-TVSDFLLLGLSEWPEEQPLLFGIFLGMYLVTMVGNLLIILAISSDPHLHTPMYFFLANLSLTDACFTSASIPKMLANIHTQSQIISYSGCLAQLYFLLMFGGLDNCLLAVMAYDRYVAICQP---------LHYSTSMSPQLCALMLGVCWVLTNCPALMHTLLLTRVAFCAQKAIPHFYCDPSALLKLACSDTHVNELMIITMGLLFLTVPLLLIVFSYVRIFWAV-FVISSPGGRWKAFSTCGSHLTVVL--LFYGSLMGVYLLPPSTYST--ERESRAAVLYMVIIPTLNPFIYSLRNRDMKEALGKLFVSGKTFFL------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TQU7-1", "uniprot_id": "Q7TQU7_MOUSE", "id": "Q7TQU7-1", "name": "", "aln": "------------------------------------MAP---ENQT-TVLEFHLMGLSEDPDLQTILFGLFLSMYLVTVFGNLLIILAIISDSHLHTPMYFFLCNLSLVDIFFCSTTVPKMLVNIQTQSRAISFTGCLVQMYAFHLFGTIDSFLLAVMAIDRLVAIAYP---------LRYSVLMSPHVCALLVGGTWVITNLQSLVHTCLMAQLTFCARSEIPHFFCDLMPLLKLSCSDTHINELVIFAFGIVMGLSPLSCILVSYICIFRAV-FRIPSAQGKWKAFSTCGSHLTVVS--LFYGTIFTGYLLPASPSSS--QKDKAAALMFGVVIPTLNPFIYSLRNKDMKAALRKLGSKAVS----------------------------------FQS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60431-1", "uniprot_id": "OR1I1_HUMAN", "id": "O60431-1", "name": "Olfactory receptor 1I1", "aln": "------------------------------------MEP---EKQT-EISEFFLQGLSEKPEHQTLLFTMFLSTYLVTIIGNALIILAIITDSHLHTPMYFFLFNLSLVDTLLSSTTVPKMLANIQAQSRAIPFVGCLTQMYAFHLFGTMDSFLLAVMAIDRFVAIVHP---------QRYLVLMCSPVCGLLLGASWMITNLQSLIHTCLMAQLTFCAGSEISHFFCDLMPLLKLSGSDTHTNELVIFAFGIVVGTSPFSCILLSYIRIFWTV-FKIPSTRGKWKAFSTCGLHLTVVS--LSYGTIFAVYLQPTSPSSS--QKDKAAALMCGVFIPMLNPFIYSIRNKDMKAALGKLIGKVAVPCPRPEQLLDVYHVPGSLLAARDTEMHPIPYPGGVQSLAGNRDME", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH06-1", "uniprot_id": "OR1P1_HUMAN", "id": "Q8NH06-1", "name": "Olfactory receptor 1P1", "aln": "-------------------------MGLTQDFFPPTSELLEGGNQT-STFEFLLWGLSDQPQQQHIFFLLFLWMYVVTVAGNLLIVLAIGTDTHLHTPMYFFLASLSCADIFSTSTTVPKALVNIQTQSRSISYAGCLAQLYFFLTFGDMDIFLPATMAYDRYVAICHL---------LHYMMIMSLHRCAFLVTACWTLTSLLAMTRTFLIFRLSLCSK-ILPGFFCDLGPLMKVSCSDAQVNELVLLFLGGAVILIPFMLILVSYIRIVSAI-LRAPSAQGRRKAFSTCDSHLVVVA--LFFGTVIRAYLCPSSSSSNSVKEDTAAAVMYTVVTPLLNPFIYSMRNKDMKAAVVRLLKGRVSFSQGQ----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGA1-1", "uniprot_id": "OR1M1_HUMAN", "id": "Q8NGA1-1", "name": "Olfactory receptor 1M1", "aln": "------------------------------------MEP---RNQT-SASQFILLGLSEKPEQETLLFSLFFCMYLVMVVGNLLIILAISIDSHLHTPMYFFLANLSLVDFCLATNTIPKMLVSLQTGSKAISYPCCLIQMYFFHFFGIVDSVIIAMMAYDRFVAICHP---------LHYAKIMSLRLCRLLVGALWAFSCFISLTHILLMARLVFCGSHEVPHYFCDLTPILRLSCTDTSVNRIFILIVAGMVIATPFVCILASYARILVAI-MKVPSAGGRKKAFSTCSSHLSVVA--LFYGTTIGVYLCPSSVLTT--VKEKASAVMYTAVTPMLNPFIYSLRNRDLKGALRKLVNRKITSSS------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VFM9-1", "uniprot_id": "OR1M1_MOUSE", "id": "Q8VFM9-1", "name": "Olfactory receptor 1M1", "aln": "------------------------------------MEP---QNHT-SASEFILLGLSEKPDHDPVLFSLFLCMYMITVVGNLLIILAISFDSHLHTPMYFFLANLSLVDFCLATNTVPKMLVNIQTRNKSISYPCCLTQMYFFHFFGIMDSVLIAVMAYDRFVAICHP---------LHYSTIMSPRLCGLLVGVPWVYSCFISLTHILLMARLVFCGKNELPHYFCDLTPLLRLSCTDTTVNKIFVLIVAGMVIATPFVCILASYARIIVAI-MKVPSAGGRKKAFSTCSSHLSVVA--LFYGTTIGVYLCPSSVRTA--VKEKASAVMYTAVTPMLNPFIYSLRNRDLKGALKKIINRKISTSS------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NH92-1", "uniprot_id": "OR1S1_HUMAN", "id": "Q8NH92-1", "name": "Olfactory receptor 1S1", "aln": "------------------MKTFS-----SFLQIGRNMHQ---GNQT-TITEFILLGFFKQDEHQNLLFVLFLGMYLVTVIGNGLIIVAISLDTYLHTPMYLFLANLSFADISSISNSVPKMLVNIQTKSQSISYESCITQMYFSIVFVVIDNLLLGTMAYDHFVAICHP---------LNYTILMRPRFGILLTVISWFLSNIIALTHTLLLIQLLFCNHNTLPHFFCDLAPLLKLSCSDTLINELVLFIVGLSVIIFPFTLSFFSYVCIIRAV-LRVSSTQGKWKAFSTCGSHLTVVL--LFYGTIVGVYFFPSSTHPE--DTDKIGAVLFTVVTPMINPFIYSLRNKDMKGALRKLINRKISSL-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGQ3-1", "uniprot_id": "OR1S2_HUMAN", "id": "Q8NGQ3-1", "name": "Olfactory receptor 1S2", "aln": "------------------MKTLC-----SFLQISRNMHQ---ENQT-TITEFILLGLSNQAEHQNLLFVLFLSMYVVTVVGNGLIIVAISLDIYLHTPMYLFLAYLSFADISSISNSVPKMLVNIQTNSQSISYESCITQMYFSIVFVVTDNLLLGTMAFDHFVAICHP---------LNYTTFMRARFGTLLTVISWFLSNIIALTHTLLLIQLLFCDHNTLPHFFCDLAPLLKLSCSDTMINELVLFIVGLSVIIFPFVLIFFSYVCIIRAV-LGVSSTQGKWKAFSTCGSHLTIAL--LFYGTTVGVYFFPSSTHPE--DTDKIGAVLFTVVTPMMNPFIYSLRNKDMKGALRKLINRKISSL-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1LV45-1", "uniprot_id": "F1LV45_RAT", "id": "F1LV45-1", "name": "Olfactory receptor", "aln": "----------------------------------RNMSQ---GNQT-TISEFILLGLSNQAEKQKFIFVIFLSMYLVTVLGNSLIILVIGLDVNLHTPMYLFLANLSFADISSSSTSVPKMLMNIQTKSQYISYEGCFTQMYFSIVFVVIDNFLLGVMAYDRYVAICHP---------LTYTSIMHSTFCLLLTVCPWALSNIVALTHTLLANQLIFCNDNTIQHFFCDLAPLLKLSCSDAMINNIVKFIVGLSVITFPFALILFSYVCIIRDV-LRISSMEGKWKAFSTCGSHLTVVF--LFYGTIIGVYFFPLSTHPE--DTDKIGAVLFTVVTPMLNPFIYSLRNKDMKGAFKKLINKSHFFLLMS----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEU7-1", "uniprot_id": "Q8VEU7_MOUSE", "id": "Q8VEU7-1", "name": "Olfactory receptor", "aln": "------------------MLPFNDEDEFSLFRYSRTMHQ---GNQT-AISGFILLGLTVGSEQQLLLFTLFLCMYLVTMVGNSLIILAIISDTHLYSPMYFFLANLSFTDICFTTTTVPKILADIQSQNPTISFVGCFTQMYFFMFLVDLDNFLLAAMAYDRYIAICHP---------LHYAALLNPKRCALLVVVPWVISNLVSVLHLSLLSRLPFCDQRVIPHFFCDLEPVLRLACSDTQINNLLILIVGGTVIFVPFVFILVSYALIGTAV-LNVPSVKGKWKTFSTCGSHLSAVS--LFYGSIVGVYFLPASSYSA--ERDKVAAIMYTVVTPMMNPFIYSLRNKDMKRALRRLLSQKSLICSW-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGR2-1", "uniprot_id": "OR1L6_HUMAN", "id": "Q8NGR2-1", "name": "Olfactory receptor 1L6", "aln": "MSYFYRLKLMKEAVLVKLPFTSLPLLLQTLSRKSRDMEIK--NYSS-STSGFILLGLSSNPQLQKPLFAIFLIMYLLAAVGNVLIIPAIYSDPRLHTPMYFFLSNLSFMDICFTTVIVPKMLVNFLSETKVISYVGCLAQMYFFMAFGNTDSYLLASMAIDRLVAICNP---------LHYDVVMKPRHCLLMLLGSCSISHLHSLFRVLLMSRLSFCASHIIKHFFCDTQPVLKLSCSDTSSSQMVVMTETLAVIVTPFLCIIFSYLRIMVTV-LRIPSAAGKWKAFSTCGSHLTAVA--LFYGSIIYVYFRPLSMYSV--VRDRVATVMYTVVTPMLNPFIYSLRNKDMKRGLKKLQDRIYR---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TRY4-1", "uniprot_id": "Q7TRY4_MOUSE", "id": "Q7TRY4-1", "name": "Olfactory receptor", "aln": "-------------------------------------MLR--ENQS-HMTEFLLLGLTSNPKQQVWLFASFLAMYLVNVIGNSVIIASIQRDARLHTPMYFFLSNLSLVDICFTTVIVPQMLVNLLTQRKTILFAQCLTQMYFFVAFGITDSFLLAAMAIDRYVAICNP---------LHYNTVMSPRRCRLLVVASWAVSHLHSLTHTILMGRLSFCGPNVIHHFFCDVQPLLTLSCSDTSINELLAFTEGSVVIMSPFIFIVVSYIYITRTV-LRVPSGEGRYKVFSTCGSHLTVVA--LFYGTIISVYIRPSSTYSV--TKDRVVTVIYTVVTPMLNPFIYSLRNKDMKQALRKLAKRTE----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A4S6-1", "uniprot_id": "D4A4S6_RAT", "id": "D4A4S6-1", "name": "", "aln": "------------------------------------MAV---TNLT-YRPQFQLLGLMDGADTHPLLFLLFLSIYLLNALGNLSMVVLVRSDGALCSPMYYFLGHLSLVDVCFTTVTVPRLLVTLLHPGQAMSFQDCFAQMYFFVALGITESYLLAAMSYDRVVAVCRP---------LHYGVVMTPWRCFVLVAASWTVAHLHSLLHTLLISALSYPRSAPVHHFFCDMTVMLSLATSDTSTAETAIFSEGLAVVLTPLILVSLSYARILVAV-LGMQTTGGRHRVFSTCGAHLVVVS--LFFGSVLSVYFRPSFGYSA--RYDRMASVVYAVVTPTLNPFIYSLRNKEVKGALKRGFRWRAAAQDE-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VFY0-1", "uniprot_id": "Q8VFY0_MOUSE", "id": "Q8VFY0-1", "name": "", "aln": "------------------------------------MAV---TNLT-YKPQFQLLGLMDGTDPHPLLFLLFLSIYLLNALGNLSMVVLVRSDGALCSPMYYFLGHLSLVDVCFTTVTVPRLLATLLHPGQAISFQACFAQMYFFVALGITESYLLAAMSYDRAVAVCRP---------LHYGAVMTPWRCFLLVAASWAVAHLHSLLHTLLISALTYPPSAPVRHFFCDMTVMLSLATSDTSAAETAIFSEGLTVVLTPLLLVSLSYARILVAV-LGIRTTGGRHRVFSTCGAHLVVVS--LFFGSVLSVYFRPSSAYSA--RYDRMASVVYAVVTPTLNPFIYSLRNKEVKSALKRGFRWRAAPQDE-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A286YEU6-1", "uniprot_id": "OR1R1_HUMAN", "id": "A0A286YEU6-1", "name": "Olfactory receptor 1R1", "aln": "------------------------------------MAP---TNLT-SAPVFLLLGLVDGTDAHPLLFLLCLGIYLLNALSNLSMVALVRSDGALRSPMYYFLGHLSLVDVCFTTVTVPRLLAGLLHPGQAISFQACFAEMYFFVALGITESYLLAAMSYDRPTAACRP---------LRYGALVTPWRCASLVRASWAVTHLHSLLHTLLLSALSYPYPTPVRPFFCDMTVMLSLATSDTSAAETAIFSEGLAVVLAPLLLVFLFLR--AHPG-RGARLAGGRRRAFSTCGAHLVAVAVALFFGSVLSVYFPPSSAYSA--RYDRLASVVYAVITPTLNPFINSLRNKEVKGALKRGLRWRAAPQEA-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LNM5-1", "uniprot_id": "A0ABK0LNM5_RAT", "id": "A0ABK0LNM5-1", "name": "", "aln": "------------------------------------MAP---VNQS-VVTMFILQNFVDDPWIQDVLFCLFFALFMMAIAGNGLIIMTIYSSANLHTPMYFFLVNLSLMDVICTVTVLPKVLQSLVA-ENAISYGGCLTQMFVFSWVLGSELLLFSAMAYDRYLAICRP---------LHYGTLMNGRACVALATFVWFTGALNSLVLTCLVLPLSFCGPNLITHFFCEIPSVLMLSCSSTFINDIMTVITDMFLTGLNFLLTMTSYVFIIASI-LRIRSAEGKKRAFSTCSAHLVVVT--LYYSTVLYTYVRPALGTAG--LLDKAVAVLYTTVTPSLNPLIYTLRNKEFKTSFKKLLFPH-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6B0Y0-1", "uniprot_id": "A0A8I6B0Y0_RAT", "id": "A0A8I6B0Y0-1", "name": "", "aln": "------------------------------------MAP---INQS-VVTMFFLQNFVDDPWIQNVLFCFFFALFVAAIAGNGLIITVIHSSANLHTPMYFFLVNLSLMDVICTVTVLPKVLQSLVA-ENAISYGGCLTQMFVFSWVLGSELLLFSAMAYDRYLAICRP---------LHYGTLMSGRVCIALATFVWFTGALNSLVLTCLVLPLSFCGPNLITHFFCEIPSVLMLSCSPTFINDIMTVIADMFLTGLNFLLTMTSYGFIIASI-LRIRSAEGKKRAFSTCSAHLVVVT--LYYSTVLYTYVRPALGTSG--LLDKVIAVLYTTVTPSLNPLIYTLRNKEFKTSFKKLLFPN-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2K0L2-1", "uniprot_id": "A0A0G2K0L2_RAT", "id": "A0A0G2K0L2-1", "name": "", "aln": "------------------------------------------MNGT-LVTEFLILGFSEMPHLRVP-LLSFLCLYMAAISGNLLIMVTVSASPALHTPMYFFLVNLAVVDILCTSTILPKLLDIMVG-GRTISYGGCMAQLFFFTWSMGAELLLFSAMAYDRFVAICCP---------LHYSTWMGPRVCAFLAGLVWSISLTNTSVNTSLVLHLPFCSSNVIEHFFCEIPPLLKLSCAPTQLNEVMAFAADVFLAVGNFSVIILSYGFIVTSI-LKIRSTEGKQRAFSTCSAHLFVVT--MYYSTIIYTYIRPASSYSL--NKDKVVSIIYTSVAPTLNPLIYTLRNKDVKVALRKLLSSC-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TRT9-1", "uniprot_id": "Q7TRT9_MOUSE", "id": "Q7TRT9-1", "name": "", "aln": "--------------------------------------M---MNGT-LVTEFLILGFSEMPHLRVPLLFSFLCLYMAAISGNLLIMVTISASPALHTPMYFFLVNLAIVDILCTSTILPKLLDSMMT-GRTISYGGCMAQLFFFTWSLGAELLLFSAMAYDRFVAICCP---------LHYSAWMGPRVCAFLAGIVWTISLTNTSVHTGLMLRLPFCSSNVIEHFFCEIPPLLKLSCAPTQLNEAMAFAADVFLAVGNFSVTILSYGFIVASI-LKIRSAEGKRRAFSTCSAHLIVVT--MYYSTVIYTYIRPSSSYSL--NKDKVVSIIYTSVAPTLNPLIYTLRNKDVKVALRRLLSCC-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGL2-1", "uniprot_id": "Q8VGL2_MOUSE", "id": "Q8VGL2-1", "name": "", "aln": "------------------------------------------MNGT-LVTEFLILGFSDMPHLRILLFLSFLCLYMAAVSGNLLIMVTISASPTLHTPMYFFLVNLAVVDILCTSTILPKLLDTMVG-GRTISYGGCMAQLFFFTWSLGVELLLFSAMAYDRFVAICCP---------LHYSTWMGPRVCAFLAGIVWAISLTNTSINSSLVLRLPFCSSNVVEHFFCEIPPLLKLSCAPTQLNEAMAFAADVFLAVGNFSVIILSYGFIVASI-LKIRSAEGKQRAFSTCSAHLIVVT--MYYSTVIYTYIRPSSSYSL--NKDKVVSIIYTSVAPTLNPLIYTLRNKDVKVALRRLFSCC-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TS01-1", "uniprot_id": "Q7TS01_MOUSE", "id": "Q7TS01-1", "name": "", "aln": "--------------------------------------M---MNFS-IVSEFMILGLTQKSELQGILFIVFLFIYLVALLGNMLIVVAIIYNTTLHTPMYILLLALAVVDIICTTSIIPKMLGTMLTSKNSISYGGCMSQLFFFTWSLGAEMVLFTTMAYDRYVAICFP---------LRYSTIMNHYTCVGLLSIVMAIAVTNSWVHTGLILRLTFCGPNIIDHFFCEIPPLLALSCSPVRVNEVMVYVADITLAVGDFTLTCISYGFIIAAI-LRIRTTEGKKKAFSTCSSHLMVVS--LYYSPVIYTYIRPASSYTF--DKDKVVAALYTLVTPTLNPIVYSFRNKEMQSGIKKVFAFLKG---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGZ3-1", "uniprot_id": "O13G1_HUMAN", "id": "Q8NGZ3-1", "name": "Olfactory receptor 13G1", "aln": "------------------------------------------MNHS-VVTEFIILGLTKKPELQGIIFLFFLIVYLVAFLGNMLIIIAKIYNNTLHTPMYVFLLTLAVVDIICTTSIIPKMLGTMLTSENTISYAGCMSQLFLFTWSLGAEMVLFTTMAYDRYVAICFP---------LHYSTIMNHHMCVALLSMVMAIAVTNSWVHTALIMRLTFCGPNTIDHFFCEIPPLLALSCSPVRINEVMVYVADITLAIGDFILTCISYGFIIVAI-LRIRTVEGKRKAFSTCSSHLTVVT--LYYSPVIYTYIRPASSYTF--ERDKVVAALYTLVTPTLNPMVYSFQNREMQAGIRKVFAFLKH---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LI97-1", "uniprot_id": "A0ABK0LI97_RAT", "id": "A0ABK0LI97-1", "name": "Olfactory receptor", "aln": "-----------------------------------------------MVIEFLFSVFPPLHEGGLLFFILLILVYAFIISGNLVIFVAVQLDLALHTPMYFFISVLSFLEIWYTTTTIPKMLSSLVSEKKTISLGGCLMQMYFFHSLGITEGCVLTAMSIDRYIAICYP---------LRYPTIMTSKLCIQLTAGSCFCGFLLVLPEIAWIATLPFCGSNKIHQIFCDFTPVLRLACTDTSLVV-IVDAIHAVEILASFLVIALSYIRIIMVI-LGMPSAEGRHKAFSTCAAHLAVFL--LFFGSVAVMYLRFSATYSV--FWDTVIAVTFVILAPFLNPIIYSLRNKEMKDAIGRLFH-RKRDARAQK---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGW6-1", "uniprot_id": "OR6K6_HUMAN", "id": "Q8NGW6-1", "name": "Olfactory receptor 6K6", "aln": "--------MKQYSVGNQHSNYRSLLFPFLCSQMTQLTAS---GNQT-MVTEFLFSMFPHAHRGGLLFFIPLLLIYGFILTGNLIMFIVIQVGMALHTPLYFFISVLSFLEICYTTTTIPKMLSCLISEQKSISVAGCLLQMYFFHSLGITESCVLTAMAIDRYIAICNP---------LRYPTIMIPKLCIQLTVGSCFCGFLLVLPEIAWISTLPFCGSNQIHQIFCDFTPVLSLACTDTFLVV-IVDAIHAAEIVASFLVIALSYIRIIIVI-LGMHSAEGHHKAFSTCAAHLAVFL--LFFGSVAVMYLRFSATYSV--FWDTAIAVTFVILAPFFNPIIYSLKNKDMKEAIGRLFHYQKRAGWAGK---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6A5L7-1", "uniprot_id": "A0A8I6A5L7_RAT", "id": "A0A8I6A5L7-1", "name": "Olfactory receptor", "aln": "------------------------------------MRI---NRTT-SVTEFLFSGLPEFEDGRFLFFIPLFFIYVFIVIGNLIVFFAVRMDTRLHNPMYNFISIFSFLEIWYTTATIPKMLSNLISKRRTISLIGCLLQMYFFHSLGNSEGILLTTMAIDRYIAICNP---------LRYPTIMTPRLCAQLSAGSCIFGFLVLLPEIAWISTLPFCGPNQIHQIFCDFEPVLRLACTDTSMIL-VEDVVHAVAIIFSVLVIAFSYIRIITVI-LRIPSGEGRRKAFSTCAAHLGVFL--MFYGSVSLMYLRFSATFPP--VLDTAIALMFAVLAPFFNPIIYSLRNKDMKTAIKKLLSSPTMLPTSAS---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGY3-1", "uniprot_id": "OR6K3_HUMAN", "id": "Q8NGY3-1", "name": "Olfactory receptor 6K3", "aln": "-------------------MCWTMPSPFTG-SSTRNMES---GNQS-TVTEFIFTGFPQLQDGSLLYFFPLLFIYTFIIIDNLLIFSAVRLDTHLHNPMYNFISIFSFLEIWYTTATIPKMLSNLISEKKAISMTGCILQMYFFHSLENSEGILLTTMAIDRYVAICNP---------LRYQMIMTPRLCAQLSAGSCLFGFLILLPEIVMISTLPFCGPNQIHQIFCDLVPVLSLACTDTSMIL-IEDVIHAVTIIITFLIIALSYVRIVTVI-LRIPSSEGRQKAFSTCAGHLMVFP--IFFGSVSLMYLRFSDTYPP--VLDTAIALMFTVLAPFFNPIIYSLRNKDMNNAIKKLFCLQKVLNKPGG---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AP46-1", "uniprot_id": "A0A8I6AP46_RAT", "id": "A0A8I6AP46-1", "name": "Olfactory receptor", "aln": "------------------------------------MDH---VNCT-WNWIFILAGFNTSGTLQQLAVFGTLCIYLLTLAGNLFIIVLVQADSGLSTPMYFFISVLSFLEIWYVSTTVPTLLHTLLHGHSPIPSAACFIQLYVFHSLGMTECYLLGVMALDRYLAICRP---------LHYHSLMSRQVQRELVLITWVAGFSAALVPAGLTATLPYC-LKEVAHYFCDLGPVMQLACVDTSWHARVYIAVIGMINTCNLVFILGLYGGIVKAV-LRLPSAASRAKAFSTCSSHITVVT--LFFGSAFIVYVGPPEIRAE--GRGKLIALVYTLFTPFFNPIIYTLRNKEVKAAFKRVTQRIKGVLG------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZIK6-1", "uniprot_id": "D3ZIK6_RAT", "id": "D3ZIK6-1", "name": "Olfactory receptor", "aln": "------------------------------------MDH---VNYT-WTRTFILAGFTTSGTLQQLSVFGTLCIYLLTIAGNIFIIVLVQADSGLSTPMYFFISVLSFLEIWYVSTSVATLLHTLLHGHSPIPSAACFIQLYVFHSLGMTECYLLSVMALDRYLAICRP---------LHYHALMSRQVKIQLVLITWVAGFSVALVPAGLTASLPYC-LKEVAHYLCDLEPVIRLACVDTSWHARVYITVIGIIITCNLVSILGLYGGIAKAV-LRLPSAASRAKAFSTCSSHITVVT--LFYGSAFIVYVGPPEIRAE--GRDKLIALVYTLFTPFFNPIIYTLRNKEVKAAFKRVTQRIQGVLS------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q8M2-1", "uniprot_id": "E9Q8M2_MOUSE", "id": "E9Q8M2-1", "name": "Olfactory receptor", "aln": "------------------------------------MDH---VNYT-WTRTFILAGFTTSGTLQHLAVFGTLCIYLLTLAGNLFIIVLIQADSGLSTPMYFFISVLSFLELWYVSTTVPTLLHTLLHGPSPIPSSACFVQLYVFHSLGMTECYLLGVMALDRYLAICRP---------LHYHALMSRQVQKQLVGVTWLAGFSAALVPAGLTASLPYC-LKEVAHYFCDLAPVMQLACVDTSWHARLYIAVIGMINTCNLTFILGLYGGIVRAV-LKLPSAASRAKAFSTCSSHITVVT--LFFGSAFIVYVGPPEIRAE--GRDKLIALVYTLLTPFFNPIIYTLRNKEVKEAFKRVTQRINAVLK------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TRV9-1", "uniprot_id": "Q7TRV9_MOUSE", "id": "Q7TRV9-1", "name": "Olfactory receptor", "aln": "------------------------------------MDH---VNYT-WTRTFILAGFTTSGALRPLAFLGTLCIYLLTLAGNLFIIVLVQADSGLSTPMYFFISVLSFLELWYVSTTVPTLLHTLLHGHSPIPSSACFVQLYVFHSLGMTECYLLGVMALDRYLAICRP---------LHYHALMSRQVQLWLAGATWVAGFSAALVPACLTASLPYC-LKEIAHYFCDLAPLMRLACVSTRWHARVHGAVIGVATGCNFVLILGLYGGILTAV-LKLPSAASRAKAFSTCSSHMTVVA--LFYASAFTVYVGSPQSRPE--GTDKLIALVYALLTPFLNPIIYSLRNKEVKEAVKRVSEKIRTLLRDT----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58HBV7-1", "uniprot_id": "A0AC58HBV7_DANRE", "id": "A0AC58HBV7-1", "name": "", "aln": "------------MFLFFMLTFLKLAQNIKRKTAMSSVNASFSQNISIVRPEYFFISGLSGIPYSSYYYIFLFVVYFISVIGNSVVLLIIAVDRSLHSPKYIGVFNLALADIGETNALIPNMMKTFLFNSQYISYNGCMANMFFVFLFNSIQSFTLVALAYDRFIAICLP---------LRYHAIVNNTSMILIFLAIWAFNSSVVASMVSMITRLSICKSNVIPSYFCDHGPIFRLACNDIKINEFFAFFISILYLTMPMVIIALSYLNIFLAL-IKITTWEGRLKALKTCVSHLLLVG--IFFLPLLCTYIAQVLLALTP-NARVISTSLSYAIPPMLNPIIYVLNTAEIKYIIRKLFKRRLRSVSDNISK-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : .* :. * : : :: : . : : *. : . : :: . * * : : : : : :: :: :.:.** *: : * : . ..*:: :.. :. . ", "identical_positions": 10, "similar_positions": 48, "identity": "2.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010308-19", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TQQ0-1", "uniprot_id": "OR4E2_MOUSE", "id": "Q7TQQ0-1", "name": "Olfactory receptor 4E2", "aln": "--------------------------------------MGALNQT-RVTEFIFLGLTDNWVLEILFFVPFTVTYMLTLLGNFLIVVTIVFTPRLHNPMYFFLSNLSFIDICHSSVTVPKMLEGLLLERKTISFDNCIAQLFFLHLFACSEIFLLTIMAYDRYVAICIP---------LHYSNVMNMKVCVQLVFALWLGGTIHSLVQTFLTIRLPYCGPNIIDSYFCDVPPVIKLACTDTYLTGILIVSNSGTISLVCFLALVTSYTVILFS--LRKQSAEGRRKALSTCSAHFMVVA--LFFGPCIFLYTRPDSSFSI----DKVVSVFYTVVTPLLNPLIYTLRNEEVKTAMKHLRQRRICS--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ADC0-1", "uniprot_id": "D4ADC0_RAT", "id": "D4ADC0-1", "name": "Olfactory receptor", "aln": "--------------------------------------MGALNQT-RVTEFVFLGLTDNWVLEILFFIPFTVTYVLTLLGNVLIVVTIVFTPRLHNPMYFFLSNLSFIDICHSSVTVPKMLEGLLLVRKTISFDNCIAQLFFLHLFACAEIFLLTIMAYDRYVAICIP---------LHYPNVMNMKVCVQLVFALWLGGTVHSLVQTFLTIRLPYCGPNTIDSYFCDVPPVIKLACTDTYLTGILIVSNSGTISLVCFLALVTSYTVILFS--LRKQSAEGRRKALSTCSAHFMVVA--LFFGPCIFIYTWPDTSFSI----DKVVSVFYTVVTPLLNPLIYTLRNEEVKTSMKHLRQRRICS--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGC2-1", "uniprot_id": "OR4E2_HUMAN", "id": "Q8NGC2-1", "name": "Olfactory receptor 4E2", "aln": "--------------------------------------MDSLNQT-RVTEFVFLGLTDNRVLEMLFFMAFSAIYMLTLSGNILIIIATVFTPSLHTPMYFFLSNLSFIDICHSSVTVPKMLEGLLLERKTISFDNCITQLFFLHLFACAEIFLLIIVAYDRYVAICTP---------LHYPNVMNMRVCIQLVFALWLGGTVHSLGQTFLTIRLPYCGPNIIDSYFCDVPLVIKLACTDTYLTGILIVTNSGTISLSCFLAVVTSYMVILVS--LRKHSAEGRQKALSTCSAHFMVVA--LFFGPCIFIYTRPDTSFSI----DKVVSVFYTVVTPLLNPFIYTLRNEEVKSAMKQLRQRQVFFTKSYT---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R0K4-1", "uniprot_id": "Q9R0K4_MOUSE", "id": "Q9R0K4-1", "name": "Olfactory receptor", "aln": "-----------------------------------MEKAVLINETSVMS-FRLTGLSTNPLVQMAVFFIFLIFYVLTLVGNILIVITIIYDRRLHTPMYFFLSNLSFIDVCHSTVTVPKMLSDTFSEEKLISFDACVVQMFFLHLFACTEIFLLTVMAYDRYVAICKP---------LQYMTIMNWKVCMMLAAALWTGGTIHSISLTSLTIKLPYCGPDEIDNFFCDVPQVIKLACTDTHIIEILIVSNSGLISVVCFVVLVVSYAVILVS--LRQQISDGKRKALSTCAAHLTVVT--LFLGHCIFIYSRPSTSLPE----DKVVSVFFTAVTPLLNPIIYTLRNEDMKSALNKLIKRREK---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C645-1", "uniprot_id": "OR4E1_HUMAN", "id": "P0C645-1", "name": "Olfactory receptor 4E1", "aln": "-----------------------------------MEEAILLNQTSLVTYFRLRGLSVNHKARIAMFSMFLIFYVLTLIGNVLIVITIIYDHRLHTPMYFFLSNLSFIDVCHSTVTVPKMLRDVWSEEKLISFDACVTQMFFLHLFACTEIFLLTVMAYDRYVAICKP---------LQYMIVMNWKVCVLLAVALWTGGTIHSIALTSLTIKLPYCGPDEIDNFFCDVPQVIKLACIDTHVIEILIVSNSGLISVVCFVVLVVSYAVILVS--LRQQISKGKRKALSTCAAHLTVVT--LFLGHCIFIYSRPSTSLPE----DKVVSVFFTAVTPLLNPIIYTLRNEEMKSALNKLVGRKERKEEK-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VGG9-1", "uniprot_id": "Q8VGG9_MOUSE", "id": "Q8VGG9-1", "name": "Olfactory receptor", "aln": "------------------------------------MDG---DNQTIVTEFILLGLTRQSEKEEVVFGLFLWMYLVTISGNLLIILAISCDPHLHTPMYFFLANLSSVDISAPSVIVPKALVNHMLGSKSISYTGCMTQIYFFITFSNMDGFLLSVMAYDRYVAICHP---------LHYTMMMRPRLCVLLVAISWAITNLHALLHTLLMVRLTFCSHNAVHHFFCDPYPILKLSCSDTFINDLMVFTIGGLVFMTPFTCIIVSYAYIFSKV-LKLKSAHGIRKALSTCGSHLTVVS--LFYGAILGIYMHPSSTYTV--Q-DTVATVIFTVVTPMVNPFIYSLRNRDIKGALRKIILRS-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGH1-1", "uniprot_id": "Q8VGH1_MOUSE", "id": "Q8VGH1-1", "name": "Olfactory receptor", "aln": "------------------------------------MDG---DNETMVAEFLLLGLSGKSEQEEVVFGMFLGMYLVTISGNLLIILAISCDPHLHTPMYFFLANLSSVDICFSSVTVPKALVNHVLGSKSISYTECMIQIYFFITFINMDGFLLSVMAYDRYVAICHP---------LHYTMMMRSRLCVLLVAISWVITNLHALLHTLLMVRLTFCSHNAVHHFFCDPYPILKLSCSDTFINDLMVFTVGGVIFLTPFSCIVVSYVYIFSKV-LKIPSARGIRKALSTCGSHLTVVS--LFYGAILGVYMRPSSSYSL--Q-DTVATVIFTVVTPLVNPFIYSLRNQDMKGALRKIMLRS-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NHA8-1", "uniprot_id": "OR1FC_HUMAN", "id": "Q8NHA8-1", "name": "Putative olfactory receptor 1F12P", "aln": "------------------------------------MEG---KNQTNISEFLLLGFSSWQQQQVLLFALFLCLYLTGLFGNLLILLAIGSDHCLHTPMYFFLANLSLVDLCLPSATVPKMLLNIQTQTQTISYPGCLAQMYFCMMFANMDNFLLTVMAYDRYVAICHP---------LHYSTIMALRLCASLVAAPWVIAILNPLLHTLMMAHLHFCSDNVIHHFFCDINSLLPLSCSDTSLNQLSVLATVGLIFVVPSVCILVSYILIVSAV-MKVPSAQGKLKAFSTCGSHLALVI--LFYGAITGVYMSPLSNHST--EKDSAASVIFMVVAPVLNPFIYSLRNNELKGTLKKTLSRPGAVAHACNPSTLGGRGGWIMRSGDRDHPG------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P30953-1", "uniprot_id": "OR1E1_HUMAN", "id": "P30953-1", "name": "Olfactory receptor 1E1", "aln": "------------------------------------MMG---QNQTSISDFLLLGLPIQPEQQNLCYALFLAMYLTTLLGNLLIIVLIRLDSHLHTPMYLFLSNLSFSDLCFSSVTIPKLLQNMQNQDPSIPYADCLTQMYFFLLFGDLESFLLVAMAYDRYVAICFP---------LHYTAIMSPMLCLALVALSWVLTTFHAMLHTLLMARLCFCADNVIPHFFCDMSALLKLAFSDTRVNEWVIFIMGGLILVIPFLLILGSYARIVSSI-LKVPSSKGICKAFSTCGSHLSVVS--LFYGTVIGLYLCSSANSST--LKDTVMAMMYTVVTPMLNPFIYSLRNRDMKGALSRVIHQKKTFFSL-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47887-1", "uniprot_id": "OR1E2_HUMAN", "id": "P47887-1", "name": "Olfactory receptor 1E2", "aln": "------------------------------------MMG---QNQTSISDFLLLGLPIQPEQQNLCYALFLAMYLTTLLGNLLIIVLIRLDSHLHTPVYLFLSNLSFSDLCFSSVTMPKLLQNMQNQDPSIPYADCLTQMYFFLYFSDLESFLLVAMAYDRYVAICFPMHYTAICFLLHYTAIMSPMLCLSVVALSWVLTTFHAMLHTLLMARLCFCADNVIPHFFCDMSALLKLACSDTRVNEWVIFIMGGLILVIPFLLILGSYARIVSSI-LKVPSSKGICKAFSTCGSHLSVVS--LFYGTVIGLYLCPSANSST--LKDTVMAMMYTVVTPMLTPFIYSLRNRDMKGALERVICKRKNPFLL-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8WZA6-1", "uniprot_id": "OR1E3_HUMAN", "id": "Q8WZA6-1", "name": "Olfactory receptor 1E3", "aln": "------------------------------------MMK---KNQTMISEFLLLGLPIQPEQQNLFYALFLAVYLTTLLGNLLVIVLIRLDSHLHMPMYLCLSNLSFSDLCFSSVTMPKLLQNMQSQNPSIPFADCLAQMYFHLFYGVLESFLLVVMAYHCYVAICFP---------LHYTTIMSPKCCLGLLTLSWLLTTAHATLHTLLMARLSFCAENVIPHFFCDTSTLLKLACSNTQVNGWVMFFMGGLILVIPFLLLIMSCARIVSTI-LRVPSTGGIQKAFSTCGPHLSVVS--LFYGTIIGLYLCPLTNHNT--VKDTVMAVMYTGVTHMLNPFIYSLRNRDMRGNPGQSLQHKENFFVFKIVIVGILPLLNLVGVVKLIMKYHSKSVA------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZVZ1-1", "uniprot_id": "D3ZVZ1_RAT", "id": "D3ZVZ1-1", "name": "Olfactory receptor", "aln": "------------------------------------MTQ---DNESTVSDFNLLGLPIRAEDQGVYSVLFLIMYLTTVLGNLLIILLIRLDPHLHTPMYFFLSHLALTDISFSSVTAPKMLMNMLTHSQSISYAGCVSQVYFYIAFSDLDSFLLTSMAYDRYVAICHP---------LHYNTIMSQNLCVLLLVMSWALSSANALVHTLLLARLSHFRNNTISHYFCELSALLKLSSSDTTINKMVILPLGTVVITLPFVLILVSYGCIGVTI-LKIPSINGIYKTLSTCGSHLCVVS--LYYGAIIGLYFVPSSNNTN--DQDAIVAVIYTVVTPMLNPFIYSLRNRDMKGALKNILSRR-LCSQ------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LIW9-1", "uniprot_id": "A0ABK0LIW9_RAT", "id": "A0ABK0LIW9-1", "name": "Olfactory receptor", "aln": "------------------------------------MME---TNQSTVSEFILLGLPIQPEDQAVYSVLFLAMYMTTVLGNLLIILLIRLDSHLHTPMYFFLSHLAFTDISFSSVTAPKMLMNMLTHSQSISYAGCVSQIYFFLLFGCIDNFLLTSMAYDRYVAICHP---------LHYTTVMSQSLCVLLVMISWVFSSTNGLVHTLLFARLSHFKDNTVHHFFCDLSALLKLSISDTTINELVILTLAVVVITVPFICILISYGHIGATI-LRTPTIQGICKALSTCGSHLCVVF--LYYGAIIGLYFFPSSNNTN--AKDVIASVLYTVVTPMLNPFIYSLRNRDMKGALKNTLSRR-LCSH------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGS3-1", "uniprot_id": "OR1J1_HUMAN", "id": "Q8NGS3-1", "name": "Olfactory receptor 1J1", "aln": "------------------------------------MSP---ENQSSVSEFLLLGLPIRPEQQAVFFALFLGMYLTTVLGNLLIMLLIQLDSHLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQHLAVFYKGCISQTYFFIFFADLDSFLITSMAYDRYVAICHP---------LHYATIMTQSQCVMLVAGSWVIACACALLHTLLLAQLSFCADHIIPHYFCDLGALLKLSCSDTSLNQLAIFTAALTAIMLPFLCILVSYGHIGVTI-LQIPSTKGICKALSTCGSHLSVVT--IYYRTIIGLYFLPPSSNTN--DKNIIASVIYTAVTPMLNPFIYSLRNKDIKGALRKLLSRSGAVAHACNLNTLGG---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3Z9I7-1", "uniprot_id": "D3Z9I7_RAT", "id": "D3Z9I7-1", "name": "Olfactory receptor", "aln": "------------------------------------MRL---KNHSSVSEFLLLGLPIRAEQSGIFFSMFLAMYLTTVLGNLLIILLIRLDSHLHTPMYFFLSHLAFTDISFSSVTVPKMLTKVPNQNIPITYEGCVSQTYFFIFFADLDSFLITSMAYDRYMAICHP---------LNYTTIMNQSRCATLVAISWIIASACALLHTLLLDQLSFCADHTIPHFFCDLGALLKLSCSDTSLNQLVIFTAGLAAIMLPFLCILISYGHIGFTI-LQVPSTKGICKALSTCGSHLSVVA--LYYGSIIGLYFLPPSNSTI--NNNIVASVMYTVVTPMLNPFIYSLRNKDMKGALRKLLSKKVEFSN------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGS2-1", "uniprot_id": "OR1J2_HUMAN", "id": "Q8NGS2-1", "name": "Olfactory receptor 1J2", "aln": "------------------------------------MSP---ENQSSVSEFLLLGLPIRPEQQAVFFTLFLGMYLTTVLGNLLIMLLIQLDSHLHTPMYFFLSHLALTDISFSSVTVPKMLMDMRTKYKSILYEECISQMYFFIFFTDLDSFLITSMAYDRYVAICHP---------LHYTVIMREELCVFLVAVSWILSCASSLSHTLLLTRLSFCAANTIPHVFCDLAALLKLSCSDIFLNELVMFTVGVVVITLPFMCILVSYGYIGATI-LRVPSTKGIHKALSTCGSHLSVVS--LYYGSIFGQYLFPTVSSSI--DKDVIVALMYTVVTPMLNPFIYSLRNRDMKEALGKLFSRATFFSW------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGS1-1", "uniprot_id": "OR1J4_HUMAN", "id": "Q8NGS1-1", "name": "Olfactory receptor 1J4", "aln": "------------------------------------MKR---ENQSSVSEFLLLDLPIWPEQQAVFFTLFLGMYLITVLGNLLIILLIRLDSHLHTPMFFFLSHLALTDISLSSVTVPKMLLSMQTQDQSILYAGCVTQMYFFIFFTDLDNFLLTSMAYDRYVAICHP---------LRYTTIMKEGLCNLLVTVSWILSCTNALSHTLLLAQLSFCADNTIPHFFCDLVALLKLSCSDISLNELVIFTVGQAVITLPLICILISYGHIGVTI-LKAPSTKGIFKALSTCGSHLSVVS--LYYGTIIGLYFLPSSSASS--DKDVIASVMYTVITPLLNPFIYSLRNRDIKGALERLFNRATVLSQ------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VGK1-1", "uniprot_id": "Q8VGK1_MOUSE", "id": "Q8VGK1-1", "name": "Olfactory receptor", "aln": "------------------------------------ME-----NESSVSEFFLQGISGFSEQQQLLYGLFLCMYLVTLTGNVLIILAIGSDPHLHTPMYFFLANLSFADMGLISSTVTKMLFNVQTRCHTISYTGCLTQMYFFLMFGDLDSFLLAVMAYDRYVAICHP---------LHYSTIMSARVCALMLALCWVLTNIVALTHTLLMARLSFCVVGEIAHFFCDITPVLKLSCSDTHVNELMVFALGGTVLMVPFVCIVISYIHIVFAI-LKVRTPGGGTKAFSTCSSHLCVVC--VFYGTLFSAYLCPPSVVST--EKDVAAAAMYTVVTPMLNPFIYSLRNKDMKGALKRLLCHRKFLS-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGK0-1", "uniprot_id": "Q8VGK0_MOUSE", "id": "Q8VGK0-1", "name": "Olfactory receptor", "aln": "------------------------------------ME-----NQSSVSEFFLRGISGFPEQQQLLYGLFLCMYLVTLTGNVLIILAISCDPHLHTPMYFFLANLSFADMGLISSAVTKMLFNVQTQRHTISYTGCLTQMYLFMMFGDLDSFFLAVMAYDRYVAICHP---------LHYSTIMSARVCALMLALCWVLTNIVALTHTLLMTRLSFCVVGEIAHFFCDITSVMKLSCSDTHVNELVLSGFGGTVLMVPFVSIVISYVRIVFAV-LRVQTSGGSSKAFSTCSSHLCVVC--VFYGTLFSVYLFPSSGETT--EKDVVAAAMYTVVTPMLNPFIYSLRNKDMKGALKRLLCHRRKFSP------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGS0-1", "uniprot_id": "OR1N1_HUMAN", "id": "Q8NGS0-1", "name": "Olfactory receptor 1N1", "aln": "------------------------------------ME-----NQSSISEFFLRGISAPPEQQQSLFGIFLCMYLVTLTGNLLIILAIGSDLHLHTPMYFFLANLSFVDMGLTSSTVTKMLVNIQTRHHTISYTGCLTQMYFFLMFGDLDSFFLAAMAYDRYVAICHP---------LCYSTVMRPQVCALMLALCWVLTNIVALTHTFLMARLSFCVTGEIAHFFCDITPVLKLSCSDTHINEMMVFVLGGTVLIVPFLCIVTSYIHIVPAI-LRVRTRGGVGKAFSTCSSHLCVVC--VFYGTLFSAYLCPPSIASE--EKDIAAAAMYTIVTPMLNPFIYSLRNKDMKGALKRLFSHRSIVSS------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VGJ8-1", "uniprot_id": "Q8VGJ8_MOUSE", "id": "Q8VGJ8-1", "name": "Olfactory receptor", "aln": "------------------------------------MGKISRVNQSVASDFLLLGLSEQPGEQPLLFGIFLGMYLVTMVGNLLIIFVISSDAHLHTPMYFFLANLSLTDACFTSASVPKMLANIYTQSQTISYSGCLTQLYFLLMFGGLDNCLLAVMAYDRYVAICQP---------LHYSTAMSPQLCALMLCTCWVLTNCPALMHTLLLTRVAFCAHTAIPHFYCDPSALLKLACSDTHINELMIITMGLVFLAVPLMLIVFSYVCISWAV-LGIPSSGGRWKAFSTCGSHLTVVL--LFYGSLMGVYLLPPSTHST--ERESRAAVLYMIVIPMLNPFIYSLRNRDMKEAMGKLFGGGKTVFLL-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGR9-1", "uniprot_id": "OR1N2_HUMAN", "id": "Q8NGR9-1", "name": "Olfactory receptor 1N2", "aln": "------------------------------------MGKPGRVNQTTVSDFLLLGLSEWPEEQPLLFGIFLGMYLVTMVGNLLIILAISSDPHLHTPMYFFLANLSLTDACFTSASIPKMLANIHTQSQIISYSGCLAQLYFLLMFGGLDNCLLAVMAYDRYVAICQP---------LHYSTSMSPQLCALMLGVCWVLTNCPALMHTLLLTRVAFCAQKAIPHFYCDPSALLKLACSDTHVNELMIITMGLLFLTVPLLLIVFSYVRIFWAV-FVISSPGGRWKAFSTCGSHLTVVL--LFYGSLMGVYLLPPSTYST--ERESRAAVLYMVIIPTLNPFIYSLRNRDMKEALGKLFVSGKTFFL------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TQU7-1", "uniprot_id": "Q7TQU7_MOUSE", "id": "Q7TQU7-1", "name": "", "aln": "------------------------------------MAP---ENQTTVLEFHLMGLSEDPDLQTILFGLFLSMYLVTVFGNLLIILAIISDSHLHTPMYFFLCNLSLVDIFFCSTTVPKMLVNIQTQSRAISFTGCLVQMYAFHLFGTIDSFLLAVMAIDRLVAIAYP---------LRYSVLMSPHVCALLVGGTWVITNLQSLVHTCLMAQLTFCARSEIPHFFCDLMPLLKLSCSDTHINELVIFAFGIVMGLSPLSCILVSYICIFRAV-FRIPSAQGKWKAFSTCGSHLTVVS--LFYGTIFTGYLLPASPSSS--QKDKAAALMFGVVIPTLNPFIYSLRNKDMKAALRKLGSKAVS----------------------------------FQS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60431-1", "uniprot_id": "OR1I1_HUMAN", "id": "O60431-1", "name": "Olfactory receptor 1I1", "aln": "------------------------------------MEP---EKQTEISEFFLQGLSEKPEHQTLLFTMFLSTYLVTIIGNALIILAIITDSHLHTPMYFFLFNLSLVDTLLSSTTVPKMLANIQAQSRAIPFVGCLTQMYAFHLFGTMDSFLLAVMAIDRFVAIVHP---------QRYLVLMCSPVCGLLLGASWMITNLQSLIHTCLMAQLTFCAGSEISHFFCDLMPLLKLSGSDTHTNELVIFAFGIVVGTSPFSCILLSYIRIFWTV-FKIPSTRGKWKAFSTCGLHLTVVS--LSYGTIFAVYLQPTSPSSS--QKDKAAALMCGVFIPMLNPFIYSIRNKDMKAALGKLIGKVAVPCPRPEQLLDVYHVPGSLLAARDTEMHPIPYPGGVQSLAGNRDME", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH06-1", "uniprot_id": "OR1P1_HUMAN", "id": "Q8NH06-1", "name": "Olfactory receptor 1P1", "aln": "-------------------------MGLTQDFFPPTSELLEGGNQTSTFEFLLWGLSDQPQQQHIFFLLFLWMYVVTVAGNLLIVLAIGTDTHLHTPMYFFLASLSCADIFSTSTTVPKALVNIQTQSRSISYAGCLAQLYFFLTFGDMDIFLPATMAYDRYVAICHL---------LHYMMIMSLHRCAFLVTACWTLTSLLAMTRTFLIFRLSLCSK-ILPGFFCDLGPLMKVSCSDAQVNELVLLFLGGAVILIPFMLILVSYIRIVSAI-LRAPSAQGRRKAFSTCDSHLVVVA--LFFGTVIRAYLCPSSSSSNSVKEDTAAAVMYTVVTPLLNPFIYSMRNKDMKAAVVRLLKGRVSFSQGQ----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGA1-1", "uniprot_id": "OR1M1_HUMAN", "id": "Q8NGA1-1", "name": "Olfactory receptor 1M1", "aln": "------------------------------------MEP---RNQTSASQFILLGLSEKPEQETLLFSLFFCMYLVMVVGNLLIILAISIDSHLHTPMYFFLANLSLVDFCLATNTIPKMLVSLQTGSKAISYPCCLIQMYFFHFFGIVDSVIIAMMAYDRFVAICHP---------LHYAKIMSLRLCRLLVGALWAFSCFISLTHILLMARLVFCGSHEVPHYFCDLTPILRLSCTDTSVNRIFILIVAGMVIATPFVCILASYARILVAI-MKVPSAGGRKKAFSTCSSHLSVVA--LFYGTTIGVYLCPSSVLTT--VKEKASAVMYTAVTPMLNPFIYSLRNRDLKGALRKLVNRKITSSS------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VFM9-1", "uniprot_id": "OR1M1_MOUSE", "id": "Q8VFM9-1", "name": "Olfactory receptor 1M1", "aln": "------------------------------------MEP---QNHTSASEFILLGLSEKPDHDPVLFSLFLCMYMITVVGNLLIILAISFDSHLHTPMYFFLANLSLVDFCLATNTVPKMLVNIQTRNKSISYPCCLTQMYFFHFFGIMDSVLIAVMAYDRFVAICHP---------LHYSTIMSPRLCGLLVGVPWVYSCFISLTHILLMARLVFCGKNELPHYFCDLTPLLRLSCTDTTVNKIFVLIVAGMVIATPFVCILASYARIIVAI-MKVPSAGGRKKAFSTCSSHLSVVA--LFYGTTIGVYLCPSSVRTA--VKEKASAVMYTAVTPMLNPFIYSLRNRDLKGALKKIINRKISTSS------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NH92-1", "uniprot_id": "OR1S1_HUMAN", "id": "Q8NH92-1", "name": "Olfactory receptor 1S1", "aln": "------------------MKTFS-----SFLQIGRNMHQ---GNQTTITEFILLGFFKQDEHQNLLFVLFLGMYLVTVIGNGLIIVAISLDTYLHTPMYLFLANLSFADISSISNSVPKMLVNIQTKSQSISYESCITQMYFSIVFVVIDNLLLGTMAYDHFVAICHP---------LNYTILMRPRFGILLTVISWFLSNIIALTHTLLLIQLLFCNHNTLPHFFCDLAPLLKLSCSDTLINELVLFIVGLSVIIFPFTLSFFSYVCIIRAV-LRVSSTQGKWKAFSTCGSHLTVVL--LFYGTIVGVYFFPSSTHPE--DTDKIGAVLFTVVTPMINPFIYSLRNKDMKGALRKLINRKISSL-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGQ3-1", "uniprot_id": "OR1S2_HUMAN", "id": "Q8NGQ3-1", "name": "Olfactory receptor 1S2", "aln": "------------------MKTLC-----SFLQISRNMHQ---ENQTTITEFILLGLSNQAEHQNLLFVLFLSMYVVTVVGNGLIIVAISLDIYLHTPMYLFLAYLSFADISSISNSVPKMLVNIQTNSQSISYESCITQMYFSIVFVVTDNLLLGTMAFDHFVAICHP---------LNYTTFMRARFGTLLTVISWFLSNIIALTHTLLLIQLLFCDHNTLPHFFCDLAPLLKLSCSDTMINELVLFIVGLSVIIFPFVLIFFSYVCIIRAV-LGVSSTQGKWKAFSTCGSHLTIAL--LFYGTTVGVYFFPSSTHPE--DTDKIGAVLFTVVTPMMNPFIYSLRNKDMKGALRKLINRKISSL-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1LV45-1", "uniprot_id": "F1LV45_RAT", "id": "F1LV45-1", "name": "Olfactory receptor", "aln": "----------------------------------RNMSQ---GNQTTISEFILLGLSNQAEKQKFIFVIFLSMYLVTVLGNSLIILVIGLDVNLHTPMYLFLANLSFADISSSSTSVPKMLMNIQTKSQYISYEGCFTQMYFSIVFVVIDNFLLGVMAYDRYVAICHP---------LTYTSIMHSTFCLLLTVCPWALSNIVALTHTLLANQLIFCNDNTIQHFFCDLAPLLKLSCSDAMINNIVKFIVGLSVITFPFALILFSYVCIIRDV-LRISSMEGKWKAFSTCGSHLTVVF--LFYGTIIGVYFFPLSTHPE--DTDKIGAVLFTVVTPMLNPFIYSLRNKDMKGAFKKLINKSHFFLLMS----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEU7-1", "uniprot_id": "Q8VEU7_MOUSE", "id": "Q8VEU7-1", "name": "Olfactory receptor", "aln": "------------------MLPFNDEDEFSLFRYSRTMHQ---GNQTAISGFILLGLTVGSEQQLLLFTLFLCMYLVTMVGNSLIILAIISDTHLYSPMYFFLANLSFTDICFTTTTVPKILADIQSQNPTISFVGCFTQMYFFMFLVDLDNFLLAAMAYDRYIAICHP---------LHYAALLNPKRCALLVVVPWVISNLVSVLHLSLLSRLPFCDQRVIPHFFCDLEPVLRLACSDTQINNLLILIVGGTVIFVPFVFILVSYALIGTAV-LNVPSVKGKWKTFSTCGSHLSAVS--LFYGSIVGVYFLPASSYSA--ERDKVAAIMYTVVTPMMNPFIYSLRNKDMKRALRRLLSQKSLICSW-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGR2-1", "uniprot_id": "OR1L6_HUMAN", "id": "Q8NGR2-1", "name": "Olfactory receptor 1L6", "aln": "MSYFYRLKLMKEAVLVKLPFTSLPLLLQTLSRKSRDMEIK--NYSSSTSGFILLGLSSNPQLQKPLFAIFLIMYLLAAVGNVLIIPAIYSDPRLHTPMYFFLSNLSFMDICFTTVIVPKMLVNFLSETKVISYVGCLAQMYFFMAFGNTDSYLLASMAIDRLVAICNP---------LHYDVVMKPRHCLLMLLGSCSISHLHSLFRVLLMSRLSFCASHIIKHFFCDTQPVLKLSCSDTSSSQMVVMTETLAVIVTPFLCIIFSYLRIMVTV-LRIPSAAGKWKAFSTCGSHLTAVA--LFYGSIIYVYFRPLSMYSV--VRDRVATVMYTVVTPMLNPFIYSLRNKDMKRGLKKLQDRIYR---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TRY4-1", "uniprot_id": "Q7TRY4_MOUSE", "id": "Q7TRY4-1", "name": "Olfactory receptor", "aln": "-------------------------------------MLR--ENQSHMTEFLLLGLTSNPKQQVWLFASFLAMYLVNVIGNSVIIASIQRDARLHTPMYFFLSNLSLVDICFTTVIVPQMLVNLLTQRKTILFAQCLTQMYFFVAFGITDSFLLAAMAIDRYVAICNP---------LHYNTVMSPRRCRLLVVASWAVSHLHSLTHTILMGRLSFCGPNVIHHFFCDVQPLLTLSCSDTSINELLAFTEGSVVIMSPFIFIVVSYIYITRTV-LRVPSGEGRYKVFSTCGSHLTVVA--LFYGTIISVYIRPSSTYSV--TKDRVVTVIYTVVTPMLNPFIYSLRNKDMKQALRKLAKRTE----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A4S6-1", "uniprot_id": "D4A4S6_RAT", "id": "D4A4S6-1", "name": "", "aln": "------------------------------------MAV---TNLTYRPQFQLLGLMDGADTHPLLFLLFLSIYLLNALGNLSMVVLVRSDGALCSPMYYFLGHLSLVDVCFTTVTVPRLLVTLLHPGQAMSFQDCFAQMYFFVALGITESYLLAAMSYDRVVAVCRP---------LHYGVVMTPWRCFVLVAASWTVAHLHSLLHTLLISALSYPRSAPVHHFFCDMTVMLSLATSDTSTAETAIFSEGLAVVLTPLILVSLSYARILVAV-LGMQTTGGRHRVFSTCGAHLVVVS--LFFGSVLSVYFRPSFGYSA--RYDRMASVVYAVVTPTLNPFIYSLRNKEVKGALKRGFRWRAAAQDE-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VFY0-1", "uniprot_id": "Q8VFY0_MOUSE", "id": "Q8VFY0-1", "name": "", "aln": "------------------------------------MAV---TNLTYKPQFQLLGLMDGTDPHPLLFLLFLSIYLLNALGNLSMVVLVRSDGALCSPMYYFLGHLSLVDVCFTTVTVPRLLATLLHPGQAISFQACFAQMYFFVALGITESYLLAAMSYDRAVAVCRP---------LHYGAVMTPWRCFLLVAASWAVAHLHSLLHTLLISALTYPPSAPVRHFFCDMTVMLSLATSDTSAAETAIFSEGLTVVLTPLLLVSLSYARILVAV-LGIRTTGGRHRVFSTCGAHLVVVS--LFFGSVLSVYFRPSSAYSA--RYDRMASVVYAVVTPTLNPFIYSLRNKEVKSALKRGFRWRAAPQDE-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A286YEU6-1", "uniprot_id": "OR1R1_HUMAN", "id": "A0A286YEU6-1", "name": "Olfactory receptor 1R1", "aln": "------------------------------------MAP---TNLTSAPVFLLLGLVDGTDAHPLLFLLCLGIYLLNALSNLSMVALVRSDGALRSPMYYFLGHLSLVDVCFTTVTVPRLLAGLLHPGQAISFQACFAEMYFFVALGITESYLLAAMSYDRPTAACRP---------LRYGALVTPWRCASLVRASWAVTHLHSLLHTLLLSALSYPYPTPVRPFFCDMTVMLSLATSDTSAAETAIFSEGLAVVLAPLLLVFLFLR--AHPG-RGARLAGGRRRAFSTCGAHLVAVAVALFFGSVLSVYFPPSSAYSA--RYDRLASVVYAVITPTLNPFINSLRNKEVKGALKRGLRWRAAPQEA-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LNM5-1", "uniprot_id": "A0ABK0LNM5_RAT", "id": "A0ABK0LNM5-1", "name": "", "aln": "------------------------------------MAP---VNQSVVTMFILQNFVDDPWIQDVLFCLFFALFMMAIAGNGLIIMTIYSSANLHTPMYFFLVNLSLMDVICTVTVLPKVLQSLVA-ENAISYGGCLTQMFVFSWVLGSELLLFSAMAYDRYLAICRP---------LHYGTLMNGRACVALATFVWFTGALNSLVLTCLVLPLSFCGPNLITHFFCEIPSVLMLSCSSTFINDIMTVITDMFLTGLNFLLTMTSYVFIIASI-LRIRSAEGKKRAFSTCSAHLVVVT--LYYSTVLYTYVRPALGTAG--LLDKAVAVLYTTVTPSLNPLIYTLRNKEFKTSFKKLLFPH-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6B0Y0-1", "uniprot_id": "A0A8I6B0Y0_RAT", "id": "A0A8I6B0Y0-1", "name": "", "aln": "------------------------------------MAP---INQSVVTMFFLQNFVDDPWIQNVLFCFFFALFVAAIAGNGLIITVIHSSANLHTPMYFFLVNLSLMDVICTVTVLPKVLQSLVA-ENAISYGGCLTQMFVFSWVLGSELLLFSAMAYDRYLAICRP---------LHYGTLMSGRVCIALATFVWFTGALNSLVLTCLVLPLSFCGPNLITHFFCEIPSVLMLSCSPTFINDIMTVIADMFLTGLNFLLTMTSYGFIIASI-LRIRSAEGKKRAFSTCSAHLVVVT--LYYSTVLYTYVRPALGTSG--LLDKVIAVLYTTVTPSLNPLIYTLRNKEFKTSFKKLLFPN-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2K0L2-1", "uniprot_id": "A0A0G2K0L2_RAT", "id": "A0A0G2K0L2-1", "name": "", "aln": "------------------------------------------MNGTLVTEFLILGFSEMPHLRVP-LLSFLCLYMAAISGNLLIMVTVSASPALHTPMYFFLVNLAVVDILCTSTILPKLLDIMVG-GRTISYGGCMAQLFFFTWSMGAELLLFSAMAYDRFVAICCP---------LHYSTWMGPRVCAFLAGLVWSISLTNTSVNTSLVLHLPFCSSNVIEHFFCEIPPLLKLSCAPTQLNEVMAFAADVFLAVGNFSVIILSYGFIVTSI-LKIRSTEGKQRAFSTCSAHLFVVT--MYYSTIIYTYIRPASSYSL--NKDKVVSIIYTSVAPTLNPLIYTLRNKDVKVALRKLLSSC-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TRT9-1", "uniprot_id": "Q7TRT9_MOUSE", "id": "Q7TRT9-1", "name": "", "aln": "--------------------------------------M---MNGTLVTEFLILGFSEMPHLRVPLLFSFLCLYMAAISGNLLIMVTISASPALHTPMYFFLVNLAIVDILCTSTILPKLLDSMMT-GRTISYGGCMAQLFFFTWSLGAELLLFSAMAYDRFVAICCP---------LHYSAWMGPRVCAFLAGIVWTISLTNTSVHTGLMLRLPFCSSNVIEHFFCEIPPLLKLSCAPTQLNEAMAFAADVFLAVGNFSVTILSYGFIVASI-LKIRSAEGKRRAFSTCSAHLIVVT--MYYSTVIYTYIRPSSSYSL--NKDKVVSIIYTSVAPTLNPLIYTLRNKDVKVALRRLLSCC-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGL2-1", "uniprot_id": "Q8VGL2_MOUSE", "id": "Q8VGL2-1", "name": "", "aln": "------------------------------------------MNGTLVTEFLILGFSDMPHLRILLFLSFLCLYMAAVSGNLLIMVTISASPTLHTPMYFFLVNLAVVDILCTSTILPKLLDTMVG-GRTISYGGCMAQLFFFTWSLGVELLLFSAMAYDRFVAICCP---------LHYSTWMGPRVCAFLAGIVWAISLTNTSINSSLVLRLPFCSSNVVEHFFCEIPPLLKLSCAPTQLNEAMAFAADVFLAVGNFSVIILSYGFIVASI-LKIRSAEGKQRAFSTCSAHLIVVT--MYYSTVIYTYIRPSSSYSL--NKDKVVSIIYTSVAPTLNPLIYTLRNKDVKVALRRLFSCC-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TS01-1", "uniprot_id": "Q7TS01_MOUSE", "id": "Q7TS01-1", "name": "", "aln": "--------------------------------------M---MNFSIVSEFMILGLTQKSELQGILFIVFLFIYLVALLGNMLIVVAIIYNTTLHTPMYILLLALAVVDIICTTSIIPKMLGTMLTSKNSISYGGCMSQLFFFTWSLGAEMVLFTTMAYDRYVAICFP---------LRYSTIMNHYTCVGLLSIVMAIAVTNSWVHTGLILRLTFCGPNIIDHFFCEIPPLLALSCSPVRVNEVMVYVADITLAVGDFTLTCISYGFIIAAI-LRIRTTEGKKKAFSTCSSHLMVVS--LYYSPVIYTYIRPASSYTF--DKDKVVAALYTLVTPTLNPIVYSFRNKEMQSGIKKVFAFLKG---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGZ3-1", "uniprot_id": "O13G1_HUMAN", "id": "Q8NGZ3-1", "name": "Olfactory receptor 13G1", "aln": "------------------------------------------MNHSVVTEFIILGLTKKPELQGIIFLFFLIVYLVAFLGNMLIIIAKIYNNTLHTPMYVFLLTLAVVDIICTTSIIPKMLGTMLTSENTISYAGCMSQLFLFTWSLGAEMVLFTTMAYDRYVAICFP---------LHYSTIMNHHMCVALLSMVMAIAVTNSWVHTALIMRLTFCGPNTIDHFFCEIPPLLALSCSPVRINEVMVYVADITLAIGDFILTCISYGFIIVAI-LRIRTVEGKRKAFSTCSSHLTVVT--LYYSPVIYTYIRPASSYTF--ERDKVVAALYTLVTPTLNPMVYSFQNREMQAGIRKVFAFLKH---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LI97-1", "uniprot_id": "A0ABK0LI97_RAT", "id": "A0ABK0LI97-1", "name": "Olfactory receptor", "aln": "----------------------------------------------MVIEFLFSVFPPLHEGGLLFFILLILVYAFIISGNLVIFVAVQLDLALHTPMYFFISVLSFLEIWYTTTTIPKMLSSLVSEKKTISLGGCLMQMYFFHSLGITEGCVLTAMSIDRYIAICYP---------LRYPTIMTSKLCIQLTAGSCFCGFLLVLPEIAWIATLPFCGSNKIHQIFCDFTPVLRLACTDTSLVV-IVDAIHAVEILASFLVIALSYIRIIMVI-LGMPSAEGRHKAFSTCAAHLAVFL--LFFGSVAVMYLRFSATYSV--FWDTVIAVTFVILAPFLNPIIYSLRNKEMKDAIGRLFH-RKRDARAQK---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGW6-1", "uniprot_id": "OR6K6_HUMAN", "id": "Q8NGW6-1", "name": "Olfactory receptor 6K6", "aln": "--------MKQYSVGNQHSNYRSLLFPFLCSQMTQLTAS---GNQTMVTEFLFSMFPHAHRGGLLFFIPLLLIYGFILTGNLIMFIVIQVGMALHTPLYFFISVLSFLEICYTTTTIPKMLSCLISEQKSISVAGCLLQMYFFHSLGITESCVLTAMAIDRYIAICNP---------LRYPTIMIPKLCIQLTVGSCFCGFLLVLPEIAWISTLPFCGSNQIHQIFCDFTPVLSLACTDTFLVV-IVDAIHAAEIVASFLVIALSYIRIIIVI-LGMHSAEGHHKAFSTCAAHLAVFL--LFFGSVAVMYLRFSATYSV--FWDTAIAVTFVILAPFFNPIIYSLKNKDMKEAIGRLFHYQKRAGWAGK---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6A5L7-1", "uniprot_id": "A0A8I6A5L7_RAT", "id": "A0A8I6A5L7-1", "name": "Olfactory receptor", "aln": "------------------------------------MRI---NRTTSVTEFLFSGLPEFEDGRFLFFIPLFFIYVFIVIGNLIVFFAVRMDTRLHNPMYNFISIFSFLEIWYTTATIPKMLSNLISKRRTISLIGCLLQMYFFHSLGNSEGILLTTMAIDRYIAICNP---------LRYPTIMTPRLCAQLSAGSCIFGFLVLLPEIAWISTLPFCGPNQIHQIFCDFEPVLRLACTDTSMIL-VEDVVHAVAIIFSVLVIAFSYIRIITVI-LRIPSGEGRRKAFSTCAAHLGVFL--MFYGSVSLMYLRFSATFPP--VLDTAIALMFAVLAPFFNPIIYSLRNKDMKTAIKKLLSSPTMLPTSAS---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NGY3-1", "uniprot_id": "OR6K3_HUMAN", "id": "Q8NGY3-1", "name": "Olfactory receptor 6K3", "aln": "-------------------MCWTMPSPFTG-SSTRNMES---GNQSTVTEFIFTGFPQLQDGSLLYFFPLLFIYTFIIIDNLLIFSAVRLDTHLHNPMYNFISIFSFLEIWYTTATIPKMLSNLISEKKAISMTGCILQMYFFHSLENSEGILLTTMAIDRYVAICNP---------LRYQMIMTPRLCAQLSAGSCLFGFLILLPEIVMISTLPFCGPNQIHQIFCDLVPVLSLACTDTSMIL-IEDVIHAVTIIITFLIIALSYVRIVTVI-LRIPSSEGRQKAFSTCAGHLMVFP--IFFGSVSLMYLRFSDTYPP--VLDTAIALMFTVLAPFFNPIIYSLRNKDMNNAIKKLFCLQKVLNKPGG---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AP46-1", "uniprot_id": "A0A8I6AP46_RAT", "id": "A0A8I6AP46-1", "name": "Olfactory receptor", "aln": "------------------------------------MDH---VNCTWNWIFILAGFNTSGTLQQLAVFGTLCIYLLTLAGNLFIIVLVQADSGLSTPMYFFISVLSFLEIWYVSTTVPTLLHTLLHGHSPIPSAACFIQLYVFHSLGMTECYLLGVMALDRYLAICRP---------LHYHSLMSRQVQRELVLITWVAGFSAALVPAGLTATLPYC-LKEVAHYFCDLGPVMQLACVDTSWHARVYIAVIGMINTCNLVFILGLYGGIVKAV-LRLPSAASRAKAFSTCSSHITVVT--LFFGSAFIVYVGPPEIRAE--GRGKLIALVYTLFTPFFNPIIYTLRNKEVKAAFKRVTQRIKGVLG------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZIK6-1", "uniprot_id": "D3ZIK6_RAT", "id": "D3ZIK6-1", "name": "Olfactory receptor", "aln": "------------------------------------MDH---VNYTWTRTFILAGFTTSGTLQQLSVFGTLCIYLLTIAGNIFIIVLVQADSGLSTPMYFFISVLSFLEIWYVSTSVATLLHTLLHGHSPIPSAACFIQLYVFHSLGMTECYLLSVMALDRYLAICRP---------LHYHALMSRQVKIQLVLITWVAGFSVALVPAGLTASLPYC-LKEVAHYLCDLEPVIRLACVDTSWHARVYITVIGIIITCNLVSILGLYGGIAKAV-LRLPSAASRAKAFSTCSSHITVVT--LFYGSAFIVYVGPPEIRAE--GRDKLIALVYTLFTPFFNPIIYTLRNKEVKAAFKRVTQRIQGVLS------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q8M2-1", "uniprot_id": "E9Q8M2_MOUSE", "id": "E9Q8M2-1", "name": "Olfactory receptor", "aln": "------------------------------------MDH---VNYTWTRTFILAGFTTSGTLQHLAVFGTLCIYLLTLAGNLFIIVLIQADSGLSTPMYFFISVLSFLELWYVSTTVPTLLHTLLHGPSPIPSSACFVQLYVFHSLGMTECYLLGVMALDRYLAICRP---------LHYHALMSRQVQKQLVGVTWLAGFSAALVPAGLTASLPYC-LKEVAHYFCDLAPVMQLACVDTSWHARLYIAVIGMINTCNLTFILGLYGGIVRAV-LKLPSAASRAKAFSTCSSHITVVT--LFFGSAFIVYVGPPEIRAE--GRDKLIALVYTLLTPFFNPIIYTLRNKEVKEAFKRVTQRINAVLK------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TRV9-1", "uniprot_id": "Q7TRV9_MOUSE", "id": "Q7TRV9-1", "name": "Olfactory receptor", "aln": "------------------------------------MDH---VNYTWTRTFILAGFTTSGALRPLAFLGTLCIYLLTLAGNLFIIVLVQADSGLSTPMYFFISVLSFLELWYVSTTVPTLLHTLLHGHSPIPSSACFVQLYVFHSLGMTECYLLGVMALDRYLAICRP---------LHYHALMSRQVQLWLAGATWVAGFSAALVPACLTASLPYC-LKEIAHYFCDLAPLMRLACVSTRWHARVHGAVIGVATGCNFVLILGLYGGILTAV-LKLPSAASRAKAFSTCSSHMTVVA--LFYASAFTVYVGSPQSRPE--GTDKLIALVYALLTPFLNPIIYSLRNKEVKEAVKRVSEKIRTLLRDT----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2I3BQG5-1", "uniprot_id": "A0A2I3BQG5_MOUSE", "id": "A0A2I3BQG5-1", "name": "Olfactory receptor", "aln": "---------------------------MSAPTSVYQGSNSVLLNQTLVTEFLLLGVTDIQELNPILFVTVLAMYFVNVAGNGAILLIVISDPRLHSPMYFFLGNLACLDICFSTVTVPKILDNFFSTSKAISFLGCITQLYFFHLLGSTEALLLAVMAFDRFVAICRP---------LHYPSIMNGQVCIQVAISIWAIPFVHALVHSILTSQLNFCGSNQIHHFFCDVKPLLELACGNTELNRWLLNTFTGTFAIGLFFLTFLSYFYIITYLFLKTRSCSMLHKALSTCASHFMVVM--IFYAPVLFIYINP--DSGSSLEKDRIIAVMYTVVTPALNPLIYTLRNKEVRGALNRKLRILL----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2I3BRX0-1", "uniprot_id": "A0A2I3BRX0_MOUSE", "id": "A0A2I3BRX0-1", "name": "Olfactory receptor", "aln": "---------------------------MSAPTSVSQEGNSVLLNHTLVTEFLLLGVTDIQELNPILFVTVLAMYFVNVAGNGAILMIVISDPRLHLPMYFFLGNLACLDICFSTVTVPKMLENFFSTSKAISFLGCITQLHFFHFLGSTEALLLTVMAFDRFVAICRP---------LHYPAIMNSQVCIQVAISIWAIPFLHALVHSILTSQLNFCGSNHIHHFFCDVKPLLELACGNTELNRWLLNTLTGTVAIGLFFLTFLSYFYIVTYLFLKTRSCSMLHKALSTCASHFMVVM--IFYAPVLFIYINP--DSGSSLEKDRIIAVMYTVVTPALNPLIYTLRNKEVRGALNRKIRILL----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58182-1", "uniprot_id": "O12D2_HUMAN", "id": "P58182-1", "name": "Olfactory receptor 12D2", "aln": "-----------------------------------------MLNTTSVTEFLLLGVTDIQELQPFLFVVFLTIYFISVTGNGAVLMIVISDPRLHSLMYFFLGNLSYLDICYSTVTLPKMLQNFLSTHKAISFLGCISQLHFFHSLGSTESMLFAVMAFDLSVAICKP---------LRYTVIMNPQLCTQMAITIWVIGFFHALLHSVMTSRLNFCGSNRIHHFLCDIKPLLKLACGNTELNQWLLSTVTGTIAMGPFFLTLLSYFYIITYLFFKTRSCSMLCKALSTCASHFMVVI--LFYAPVLFTYIHP--ALESFMDQDRIVAIMYTVVTPVLNPLIYTLRNKEVKGALGRVIRRL-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VG96-1", "uniprot_id": "Q8VG96_MOUSE", "id": "Q8VG96-1", "name": "Olfactory receptor", "aln": "-----------------------------------------MENSTSVDEFLLLGLTSVQKLQPIIFVMFLTIYLLNLVGNGVILMIVTLERRLHSPMYFFLGNLSCLDICYSSVTLPKVLINLLSRRRAISFLGCITQLYFFHFLGSTEAILLAVMAFDRFVAICSP---------LRYTAIMNPQLCILLAATAWFTSFFYALLHSVMTAHLNFCHSHKLSHFFCDVKPLLEVACGNTVLNQWLLSVVTGSISMGAFLLILLSYFYIIAFLLFKNRSCRMLKKALSTCTSHFMVVC--LFYGPVGFTYIRPATASASSMSEDRVVAIIYSAVTPVLNPLIYTLRNKEVMLALKKNFGKKLFKGN------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGF7-1", "uniprot_id": "O12D3_HUMAN", "id": "Q9UGF7-1", "name": "Olfactory receptor 12D3", "aln": "-----------------------------------------MENVTTMNEFLLLGLTGVQELQPFFFGIFLIIYLINLIGNGSILVMVVLEPQLHSPMYFFLGNLSCLDISYSSVTLPKLLVNLVCSRRAISFLGCITQLHFFHFLGSTEAILLAIMAFDRFVAICNP---------LRYTVIMNPQVCILLAAAAWLISFFYALMHSVMTAHLSFCGSQKLNHFFYDVKPLLELACSDTLLNQWLLSIVTGSISMGAFFLTLLSCFYVIGFLLFKNRSCRILHKALSTCASHFMVVC--LFYGPVGFTYIRP--ASATSMIQDRIMAIMYSAVTPVLNPLIYTLRNKEVMMALKKIFGRKLFKDWQQHH--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B4K9-1", "uniprot_id": "A0A8M2B4K9_DANRE", "id": "A0A8M2B4K9-1", "name": "", "aln": "---------------MQSYRKLARNNKSKSAMSSVNASFSQNISIVHPENFFIIGLTG-IQHSGYYYIFLFFTYFISVIGNSVVLLIIALERNLHSAKYIGVFNLALADIGETSALIPNMMKNFLFDSQYISYNGCMANMFFVFLFSSMQSFTLVVMAYDRLIAICLP---------LRYHAIVNNTSMILMTLAIWAFNTFVVALMVSLINRLSFCESNMIQSYFCDHGPVFRLACNDNSMNKIMAYVISVLYILAPMVVIVFSYLAIFLAL-IKITTWEGRLKALKTCVSHLLLVG--IFFLPVCCTYIAQVLLYLTP-NARIISTSFSYAVPPVLNPIIYVLNTAEIKDIIKKMIKNKSAPIRENISK-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . : .* :. * : : :: : . : : *. : . : :: . * * : : : : : :: :: :.:.** *: : * : . ..*:: :.. :. . ", "identical_positions": 11, "similar_positions": 48, "identity": "2.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010308-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NGT7-1", "uniprot_id": "O2A12_HUMAN", "id": "Q8NGT7-1", "name": "Olfactory receptor 2A12", "aln": "--------MESNQTWITEVILLGFQ-VDPALELFLFGFFLLFYSLTLMGNGIILGLIYLDSRLHTPMYVFLSHLAIVDMSYASSTVPKMLANLVMHK-KVISFAPCILQTFLYLAFAITECLILVMMCYDRYVAICHPLQYTLIMNWRVCTVLASTCWIFSFLLALVHITLILRLPFCGPQKINHFFCQIMSVFKLACADTRLNQVVLFAGSAFILVGPLCLVLVSYLHILVAILRIQSGEGRRKAFSTCSSHLCVVGLFFGSAIVMYMAPKS--SHSQERRKILSLFYSLFNPILNPLIYSLRNAEVKGALKRVLWKQRSM---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96R48-1", "uniprot_id": "OR2A5_HUMAN", "id": "Q96R48-1", "name": "Olfactory receptor 2A5", "aln": "--------MTKNQTWVTEFILLGFP-LSLRIQMLLSGLFSLLYVFTLLGNGAILGLIWLDSRLHTPMYFFLSHLAIIDISYASNNVPKMLTNLGLNKRKTISFVPCTMQTFLYMAFAHTECLILVMMSYDRYMAICHPLQYSVIMRWGVCTVLAVTSWACGSLLALVHVVLILRLPFCGPHEINHFFCEILSVLKLACADTWLNQVVIFAASVFILVGPLCLVLVSYSRILAAILRIQSGEGRRKAFSTCSSHLCMVGLFFGSAIVMYMAPKS--RHPEEQQKVLSLFYSLFNPMLNPLIYSLRNAEVKGALKRVLWKQRSK---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TRW8-1", "uniprot_id": "Q7TRW8_MOUSE", "id": "Q7TRW8-1", "name": "Olfactory receptor", "aln": "----MESKFESNGTAVTEFILLGLV-ETAGLQPVIFVVFLFAYLLTVGGNLSILAAVFVEPKLHTPMYFFLGNLSMLDVGCISVTVPSMLGRLLSHK-RTVPYGACLTQLFFFHQLAGVDCFLLTAMAYDRFLAICRPLTYSTRMNHTVQRILVATSWACAFSNALTHTVAISTLNFCGPNVINHFYCDLPQLFQLSCSSTQLNELLLFGLGVLMAGAPVILIVTSYIHVAAAVLRIQSSEGRKKAFSTCSSHLTVVGIFYGTGVFSYMRLGS--VEASDKDKGIGILNTVISPMLNPLIYSLRNPDVQGALRRVLTGKRDLA--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VEY9-1", "uniprot_id": "Q8VEY9_MOUSE", "id": "Q8VEY9-1", "name": "Olfactory receptor", "aln": "-------MEAENHTAIVHFLLIGLS-EDPKIQSVLFGLFLSMFLITMLGNFLIVLVTSCDSHLHTPMYFFLCNLSFVDICLTSTTIPKMLVNIYMHT-MKISYTECLTQVYFFNNFLGMDNFLLTIMAYDRFVAICHPLNYTVIMNPRICGLLVLLSWIIMFWVSLIHMLLMKQLNFSTSTEIPHFFCELTELLRVARSDTHINNIFLYLVTAVLGMFPVIGIAFSYFHIVSALMKMSSIKNKYKAFSTCGSHLCVVSMFYGTGFVVHLSSAV--AHSSKRNTITSIMYTVVTPMLNPFIYSLRNKDVKGALVRLLRRVKFCP--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFJ4-1", "uniprot_id": "Q8VFJ4_MOUSE", "id": "Q8VFJ4-1", "name": "Olfactory receptor", "aln": "-------MEVKNKSVVLDIFLHGLT-DDIELQPFIFGFFLCMYLITIFGNLLIMLAIICDSHLHKPMYFFLCHLAFNDMYLISITVPKLLVNVQTQD-QRITLAGCLSQGCFVAVCFIFECFLLGIMAYDRYIAICFPLRYTVLINPFFCVIVVLISLFISIVNGLLHSLMVLHLSFCTDLEILHFFCEIAQILKLACSDNLINNILIFVTASSFAGVPLCGIIFSYVHIVSTVLKMPSSEGKYKAFSTCGSHLSVVSLFYGTGFGVYITSVV--IDSPKEIAIASVMYSIVPPMLNPFVYSLKNRDMKEALKKVIGRTVSLP--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGH0-1", "uniprot_id": "Q8VGH0_MOUSE", "id": "Q8VGH0-1", "name": "Olfactory receptor", "aln": "-------MVRENQSTAIEFLLLGIA-GQSKEEEVIFGMFLWMYLVTVCGNLLIILAISCDPHLHTPMYFFLANLSSVDICFSSVTVPKALVNYMLGI-KTISYTECMTQIYFFITFINMDGFLLSVMAYDRYVAICHPLHYTMMMRPRLCVLLVAISWAITNLHALLHTLLMVRLTFCSHNAMHHFFCDPYPILKLSCSDTFINDITAFTVGGLTSITPFTCITVSYGYILSNVLKFPSIQGIRKALSTCGSHLTVVSLFYGAILGVYMHPSS--TYSVQD-MVATAFFTVVTPMVNPFIYSLRNRDVKGALRKLMCRRLTSSRFYN----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VET4-1", "uniprot_id": "Q8VET4_MOUSE", "id": "Q8VET4-1", "name": "Olfactory receptor", "aln": "-------MDNTNYSVVSEFVLLGLS-SSRELQIFYFVFFSMLYIVIILGNLLIIIAVTSDSSLHSPMYFLLGNLSFFDICQASFATPKMIVDFLSEH-KTISFSGCIAQIFFIHLFTGGEMVILVSMAYDRYVAICKPLHYMTIMNQTTCTALVVISWAVGLVHTLSQLSFTVKLSFCGPNEVDSFFCDLPRVVKLACIDSYITEILIVVNSGILSLSTFSLLVSSYVIILVTVW-FKSSAAMAKAFSTLAAHIMVVVLFFGPCIFIYVWPFT--TYPVDK--ILAIFYTVFTPILNPIIYTLRNRDMKAVMGKIAAHYLRPPKVAEMSFVARISLY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGE7-1", "uniprot_id": "Q8VGE7_MOUSE", "id": "Q8VGE7-1", "name": "Olfactory receptor", "aln": "-------MDGSNRSLVSEFVLLGLA-RSQNLQVLLFIIFLVVYLLILSGNTIVMFLIITDKNLHSPMYFFLANLSFVDMWLSSATTPKMITDFLKEP-KIISFAGCMSQVFFDHCVGAVEMLLLVVMAYDRYVAICKPLHYFTIMSLKRCAGLVLTSWAIAFVHAMSQLLAVVQLPLCGHMEIDSFFCDIPLIIKLACMDSHILDIYMNVDCGFVVVTCFILLLISYTYILLTVR-QSSKAGASKALSTCTAHITVVMIFFVPCIFIYVWPLS--ITWLDK--FLAVFYTVFAPLLNPAIYTLRNKEMRNAVKKLKNHFMDYKGNT-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9Q7E7-1", "uniprot_id": "E9Q7E7_MOUSE", "id": "E9Q7E7-1", "name": "Olfactory receptor", "aln": "-------MDKKNQTKVTEFYFSDFP-QFEDGGLLLFILLLCVYLFIVVGDAVIFLDVQLDVRLHNPMYSFISIFSFLEICYTTVTIPQMLYNLVSKE-KTISFIGCLLQMYFFHSFGVTESLVLTIMAIDRYVAICNPLRYAIIITPKLCTQLSTGSFTLGFLMLLPEIVWISTLPFCGPNQIHQLFCDLEPVLLLACTDTSM-ILVEDVIHAISILSCVSIISLSYLRIITVVLKIPSGESRQKAFSTCTAHITIFVLFFGSVALMYLRFSV--TFQPLLEKVIALMFAVLAPFVNPIIYSLRNKDMKDAIKKMFGSQKILTVSGS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9I8Z6-1", "uniprot_id": "Q9I8Z6_DANRE", "id": "Q9I8Z6-1", "name": "Olfactory receptor", "aln": "MGSRSNVETYQNTTIITEFVLRGFPGLPPEYHGSVGALLFILYLVLATGNIFIIVFVMIEKSIQKPTYIIFCNLAMADLALGTTTYPRVIAKYWMSD-KIISFSGCFTQMFFVHFLGATNSFLMALMALDRFIAICNPLRYHTLIKNSTILIICAFVWTANMLQLVGVTLLSLSVKYCGSNVIPHCYCDHVSISKLACGDAATMKVTSTAIAMFVLWGPLSFILFSYVSIIISVSKISKSEGRYKTFSTCTPQLLIICLYYLPRTFVYITNISGYELSTDTRMVVSMMYSLIPAVINPFIYCFRTKEIKEAIFKRFKKNKVDRKISLG---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .. : .: .: : . *: :. : ::.* * :: :: :: : * : :. * * : : .:: *. **::*** ** * : : : : . : :*: : :: . : . : ** : : . *::** .:: :. ::: . :: : ::. ..:** :* ::. ::: .: : ", "identical_positions": 25, "similar_positions": 83, "identity": "7.42%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010308-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IF42-1", "uniprot_id": "OR2A2_HUMAN", "id": "Q6IF42-1", "name": "Olfactory receptor 2A2", "aln": "--------------------------------------------------ME-GNQTW----ITDITLLGFQVGPALAIL-LCGLFSVFYTLTLLGNGVIFGIICLDSK-LHTPMYFFLSHLAIIDMSYASNNVPKMLANLMNQKRTISFVPCIMQTFLYLAFAVTECLILVVMSYDRYVAICHPFQYTVIMSWRVCTILVLTSWSCGFALSLVHEILLLRLPFCGPRDVNHLFCEILSVLKLACADTWVNQVVIFATCVFVLVGPLSLILVSYMHILGAILKIQTKEGRIKAFSTCSSHLCVVGLFFGIAMVVYMVPDSNQREE-QEKMLSLFHSVFNPMLNPLIYS------------------LRNAQLKG-----------ALHRALQRKRSMRTVYGLCL-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96R47-1", "uniprot_id": "O2A14_HUMAN", "id": "Q96R47-1", "name": "Olfactory receptor 2A14", "aln": "--------------------------------------------------ME-GNKTW----ITDITLPRFQVGPALEIL-LCGLFSAFYTLTLLGNGVIFGIICLDCK-LHTPMYFFLSHLAIVDISYASNYVPKMLTNLMNQESTISFFPCIMQTFLYLAFAHVECLILVVMSYDRYADICHPLRYNSLMSWRVCTVLAVASWVFSFLLALVPLVLILSLPFCGPHEINHFFCEILSVLKLACADTWLNQVVIFAACVFILVGPLCLVLVSYLRILAAILRIQSGEGRRKAFSTCSSHLCVVGLFFGSAIVTYMAPKSRHPEE-QQKVLSLFYSLFNPMLNPLIYS------------------LRNAEVKG-----------ALRRALRKERLT---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGT9-1", "uniprot_id": "OR2A1_HUMAN", "id": "Q8NGT9-1", "name": "Olfactory receptor 2A1/2A42", "aln": "--------------------------------------------------MG-ENQTM----VTEFLLLGFLLGPRIQML-LFGLFSLFYIFTLLGNGAILGLISLDSR-LHTPMYFFLSHLAVVDIAYTRNTVPQMLANLLHPAKPISFAGCMTQTFLCLSFGHSECLLLVLMSYDRYVAICHPLRYSVIMTWRVCITLAVTSWTCGSLLALAHVVLILRLPFSGPHEINHFFCEILSVLRLACADTWLNQVVIFAACVFFLVGPPSLVLVSYSHILAAILRIQSGEGRRKAFSTCSSHLCVVGLFFGSAIIMYMAPKSRHPEE-QQKVFFLFYSFFNPTLNPLIYS------------------LRNGEVKG-----------ALRRALGKESHS---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGY7-1", "uniprot_id": "O10J6_HUMAN", "id": "Q8NGY7-1", "name": "Putative olfactory receptor 10J6", "aln": "--------------------------------------------------MRRKNLTE----VTEFVFLGFSRFHKHHIT-LFVVFLILYTLTVAGNAIIMTIICIDRH-LHTPMYFFLSMLASSKTVYTLFIIPQMLSSFVTQTQPISLAGCTTQTFFFVTLAINNCFLLTVMGYDHYMAICNPLRYRVITSKKVCVQLVCGAFSIGLAMAAVQVTSIFTLPFCHT-VVGHFFCDILPVMKLSCINTTINEIINFVVRLFVILVPMGLVFISYVLIISTVLKIASAEGWKKTFATCAFHLTVVIVHYGCASIAYLMPKSENSIE-QDLLLSVT------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9Q7E7-1", "uniprot_id": "E9Q7E7_MOUSE", "id": "E9Q7E7-1", "name": "Olfactory receptor", "aln": "--------------------------------------------------MDKKNQTK----VTEFYFSDFPQFEDGGLL-LFILLLCVYLFIVVGDAVIFLDVQLDVR-LHNPMYSFISIFSFLEICYTTVTIPQMLYNLVSKEKTISFIGCLLQMYFFHSFGVTESLVLTIMAIDRYVAICNPLRYAIIITPKLCTQLSTGSFTLGFLMLLPEIVWISTLPFCGPNQIHQLFCDLEPVLLLACTDTSM-ILVEDVIHAISILSCVSIISLSYLRIITVVLKIPSGESRQKAFSTCTAHITIFVLFFGSVALMYLRFSVTFQPL-LEKVIALMFAVLAPFVNPIIYS------------------LRNKDMKD-----------AIKKMFGSQKILTVSGS----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47881-1", "uniprot_id": "OR3A1_HUMAN", "id": "P47881-1", "name": "Olfactory receptor 3A1", "aln": "--------------------------------------------------MQPESGANGTV-IAEFILLGLLEAPGLQPV-VFVLFLFAYLVTVRGNLSILAAVLVEPK-LHTPMYFFLGNLSVLDVGCISVTVPSMLSRLLSRKRAVPCGACLTQLFFFHLFVGVDCFLLTAMAYDRFLAICRPLTYSTRMSQTVQRMLVAASWACAFTNALTHTVAMSTLNFCGPNVINHFYCDLPQLFQLSCSSTQLNELLLFAVGFIMAGTPMALIVISYIHVAAAVLRIRSVEGRKKAFSTCGSHLTVVAIFYGSGIFNYMRLGSTKLSD-KDKAVGIFNTVINPMLNPIIYS------------------FRNPDVQS-----------AIWRMLTGRRSLA--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TRW8-1", "uniprot_id": "Q7TRW8_MOUSE", "id": "Q7TRW8-1", "name": "Olfactory receptor", "aln": "--------------------------------------------------MESKFESNGTA-VTEFILLGLVETAGLQPV-IFVVFLFAYLLTVGGNLSILAAVFVEPK-LHTPMYFFLGNLSMLDVGCISVTVPSMLGRLLSHKRTVPYGACLTQLFFFHQLAGVDCFLLTAMAYDRFLAICRPLTYSTRMNHTVQRILVATSWACAFSNALTHTVAISTLNFCGPNVINHFYCDLPQLFQLSCSSTQLNELLLFGLGVLMAGAPVILIVTSYIHVAAAVLRIQSSEGRKKAFSTCSSHLTVVGIFYGTGVFSYMRLGSVEASD-KDKGIGILNTVISPMLNPLIYS------------------LRNPDVQG-----------ALRRVLTGKRDLA--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47893-1", "uniprot_id": "OR3A2_HUMAN", "id": "P47893-1", "name": "Olfactory receptor 3A2", "aln": "--------------------------------------------MSLQKLMEPEAGTNRTA-VAEFILLGLVQTEEMQPV-VFVLLLFAYLVTTGGNLSILAAVLVEPK-LHAPMYFFLGNLSVLDVGCITVTVPAMLGRLLSHKSTISYDACLSQLFFFHLLAGMDCFLLTAMAYDRLLAICQPLTYSTRMSQTVQRMLVAASLACAFTNALTHTVAMSTLNFCGPNEVNHFYCDLPQLFQLSCSSTQLNELLLFAVGFIMAGTPLVLIITAYSHVAAAVLRIRSVEGRKKAFSTCGSHLTVVCLFFGRGIFNYMRLGSEEASD-KDKGVGVFNTVINPMLNPLIYS------------------LRNPDVQG-----------ALWQIFLGRRSLT--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47888-1", "uniprot_id": "OR3A3_HUMAN", "id": "P47888-1", "name": "Olfactory receptor 3A3", "aln": "--------------------------------------------MSLQKLMEPEAGTNRTA-VAEFILLGLVQTEEMQPV-VFVLLLFAYLVTTGGNLSILAAVLVEPK-LHAPMYFFLGNLSVLDVGCITVTVPAMLGRLLSHKSTISYDACLSQLFFFHLLAGMDCFLLTAMAYDRLLAICQPLTYSTRMSQTVQRMLVAASWACAFTNALTHTVAMSTLNFCGPNEVNHFYCDLPQLFQLSCSSTQLNELLLFVAAAFMAVAPLVFISVSYAHVVAAVLQIRSAEGRKKAFSTCGSHLTVVGIFYGTGVFSYMRLGSVESSD-KDKGVGVFMTVINPMLNPLIYS------------------LRNTDVQG-----------ALCQLLVGKRSLT--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47883-1", "uniprot_id": "OR3A4_HUMAN", "id": "P47883-1", "name": "Putative olfactory receptor 3A4", "aln": "--------------------------------------------------MDLGNSGNDSV-VTKFVLLGLTETAALQPI-LFVIFLLAYVTTIGGTLSILAAILMETK-LHSPMYFFLGNLSLPDVGCVSVTVPAMLSHFISNDRSIPYKACLSELFFFHLLAGADCFLLTIMAYDRYLAICQSLTYSSRMSWGIQQALVGMSCVFSFTNALTQTVALSPLNFCGPNVINHFYCDLPQPFQLSCSSVHLNGQLLFVAAAFMGVAPLVLITVSYAHVAAAVLRIRSAEGRKKAFSTCSSHLTVVGIFYGTGVFSYTRLGSVESSD-KDKGIGILNTVISPMLNPLIYWTSLLDVGCISHCSSDAGVSPGPPVQSSLCCLQF---TALLSPPPGWGGLSPLNSHGL-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VEY9-1", "uniprot_id": "Q8VEY9_MOUSE", "id": "Q8VEY9-1", "name": "Olfactory receptor", "aln": "--------------------------------------------------MEAENHTA----IVHFLLIGLSEDPKIQSV-LFGLFLSMFLITMLGNFLIVLVTSCDSH-LHTPMYFFLCNLSFVDICLTSTTIPKMLVNIYMHTMKISYTECLTQVYFFNNFLGMDNFLLTIMAYDRFVAICHPLNYTVIMNPRICGLLVLLSWIIMFWVSLIHMLLMKQLNFSTSTEIPHFFCELTELLRVARSDTHINNIFLYLVTAVLGMFPVIGIAFSYFHIVSALMKMSSIKNKYKAFSTCGSHLCVVSMFYGTGFVVHLSSAVAHSSK-RNTITSIMYTVVTPMLNPFIYS------------------LRNKDVKG-----------ALVRLLRRVKFCP--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFJ4-1", "uniprot_id": "Q8VFJ4_MOUSE", "id": "Q8VFJ4-1", "name": "Olfactory receptor", "aln": "--------------------------------------------------MEVKNKSV----VLDIFLHGLTDDIELQPF-IFGFFLCMYLITIFGNLLIMLAIICDSH-LHKPMYFFLCHLAFNDMYLISITVPKLLVNVQTQDQRITLAGCLSQGCFVAVCFIFECFLLGIMAYDRYIAICFPLRYTVLINPFFCVIVVLISLFISIVNGLLHSLMVLHLSFCTDLEILHFFCEIAQILKLACSDNLINNILIFVTASSFAGVPLCGIIFSYVHIVSTVLKMPSSEGKYKAFSTCGSHLSVVSLFYGTGFGVYITSVVIDSPK-EIAIASVMYSIVPPMLNPFVYS------------------LKNRDMKE-----------ALKKVIGRTVSLP--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47884-1", "uniprot_id": "OR1D4_HUMAN", "id": "P47884-1", "name": "Olfactory receptor 1D4", "aln": "--------------------------------------------------MDGDNQSE----NSQFLLLGISESPEQQQI-LFWMFLSMYLVTVLGNVLIILAISSDSH-LHTPMYFFLANLSFTDLFFVTNTIPKMLVNFQSQNKAISYAGCLTQLYFLVSLVTLDNLILAVMAYDRYVAICCPLHYVTAMSPGLCVLLLSLCWGLSVLYGLLLTFLLTRVTFCGPREIHYLFCDMYILLWLACSNTHIIHTALIATGCFIFLTLLGFMTTSYVRIVRTILQMPSASKKYKTFSTCASHLGVVSLFYGTLAMVYLQPLHTYSMK-D-SVATVMYAVLTPMMNPFIYS------------------LRNKDMHG-----------APGRVLWRPFQRP--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P58170-1", "uniprot_id": "OR1D5_HUMAN", "id": "P58170-1", "name": "Olfactory receptor 1D5", "aln": "--------------------------------------------------MDGDNQSE----NSQFLLLGISESPEQQRI-LFWMFLSMYLVTVLGNVLIILAISSDSH-LHTPMYFFLANLSFTDLFFVTNTIPKMLVNFQSQNKAISYAGCLTQLYFLVSLVTLDNLILAVMAYDRYVATCCPLHYVTAMSPGLCVLLLSLCWGLSVLYGLLLTFLLTRVTFCGPREIHYLFCDMYILLWLACSNTHIIHTALIATGCFIFLTPLGFMTTSYVRIVRTILQMPSASKKYKTFSTCASHLGVVSLFYGTLAMVYLQPLHTYSMK-D-SVATVMYAVLTPMMNPFIYR------------------LRNKDMHG-----------APGRVLWRPFQRPK-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH94-1", "uniprot_id": "OR1L1_HUMAN", "id": "Q8NH94-1", "name": "Olfactory receptor 1L1", "aln": "MERNHNPDNCNVLNFFFADKKNKRRNFGQIVSDVGRICYSVSLSLGEPTTMGRNNLTR----PSEFILLGLSSRPEDQKP-LFAVFLPIYLITVIGNLLIILAIRSDTR-LQTPMYFFLSILSFVDICYVTVIIPKMLVNFLSETKTISYSECLTQMYFFLAFGNTDSYLLAAMAIDRYVAICNPFHYITIMSHRCCVLLLVLSFCIPHFHSLLHILLTNQLIFCASNVIHHFFCDDQPVLKLSCSSHFVKEITVMTEGLAVIMTPFSCIIISYLRILITVLKIPSAAGKRKAFSTCGSHLTVVTLFYGSISYLYFQPLSNYTV--KDQIATIIYTVLTPMLNPFIYS------------------LRNKDMKQ-----------GLAKLMHRMKCQ---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH93-1", "uniprot_id": "OR1L3_HUMAN", "id": "Q8NH93-1", "name": "Olfactory receptor 1L3", "aln": "--------------------------------------------------MGMSNLTR----LSEFILLGLSSRSEDQRP-LFALFLIIYLVTLMGNLLIILAIHSDPR-LQNPMYFFLSILSFADICYTTVIVPKMLVNFLSEKKTISYAECLAQMYFFLVFGNIDSYLLAAMAINRCVAICNPFHYVTVMNRRCCVLLLAFPITFSYFHSLLHVLLVNRLTFCTSNVIHHFFCDVNPVLKLSCSSTFVNEIVAMTEGLASVMAPFVCIIISYLRILIAVLKIPSAAGKHKAFSTCSSHLTVVILFYGSISYVYLQPLSSYTV--KDRIATINYTVLTSVLNPFIYS------------------LRNKDMKR-----------GLQKLINKIKSQMSRFSTKTNKICGP-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGR8-1", "uniprot_id": "OR1L8_HUMAN", "id": "Q8NGR8-1", "name": "Olfactory receptor 1L8", "aln": "--------------------------------------------------MERINHTSS---VSEFILLGLSSRPEDQKT-LFVLFLIVYLVTITGNLLIILAIRFNPH-LQTPMYFFLSFLSLTDICFTTSVVPKMLMNFLSEKKTISYAGCLTQMYFLYALGNSDSCLLAVMAFDRYVAVCDPFHYVTTMSHHHCVLLVAFSCSFPHLHSLLHTLLLNRLTFCDSNVIHHFLCDLSPVLKLSCSSIFVNEIVQMTEAPIVLVTRFLCIAFSYIRILTTVLKIPSTSGKRKAFSTCGFYLTVVTLFYGSIFCVYLQPPSTYAV--KDHVATIVYTVLSSMLNPFIYS------------------LRNKDLKQ-----------GLRKLMSKRS-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y585-1", "uniprot_id": "OR1A2_HUMAN", "id": "Q9Y585-1", "name": "Olfactory receptor 1A2", "aln": "--------------------------------------------------MKKENQSF----NLDFILLGVTSQQEQNNV-FFVIFLCIYPITLTGNLLIILAICADIR-LHNPMYFLLANLSLVDIIFSSVTIPKVLANHLLGSKFISFGGCLMQMYFMIALAKADSYTLAAMAYDRAVAISCPLHYTTIMSPRSCILLIAGSWVIGNTSALPHTLLTASLSFCGNQEVANFYCDIMPLLKLSCSDVHFNVKMMYLGVGVFSL-PLLCIIVSYVQVFSTVFQVPSTKSLFKAFCTCGSHLTVVFLYYGTTMGMYFRPLTSYSP--KDAVITVMYVAVTPALNPFIYS------------------LRNWDMKA-----------ALQKLFSKRISS---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9P1Q5-1", "uniprot_id": "OR1A1_HUMAN", "id": "Q9P1Q5-1", "name": "Olfactory receptor 1A1", "aln": "--------------------------------------------------MRENNQSS----TLEFILLGVTGQQEQEDF-FYILFLFIYPITLIGNLLIVLAICSDVR-LHNPMYFLLANLSLVDIFFSSVTIPKMLANHLLGSKSISFGGCLTQMYFMIALGNTDSYILAAMAYDRAVAISRPLHYTTIMSPRSCIWLIAGSWVIGNANALPHTLLTASLSFCGNQEVANFYCDITPLLKLSCSDIHFHVKMMYLGVGIFSV-PLLCIIVSYIRVFSTVFQVPSTKGVLKAFSTCGSHLTVVSLYYGTVMGTYFRPLTNYSL--KDAVITVMYTAVTPMLNPFIYS------------------LRNRDMKA-----------ALRKLFNKRISS---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VGH0-1", "uniprot_id": "Q8VGH0_MOUSE", "id": "Q8VGH0-1", "name": "Olfactory receptor", "aln": "--------------------------------------------------MVRENQST----AIEFLLLGIAGQSKEEEV-IFGMFLWMYLVTVCGNLLIILAISCDPH-LHTPMYFFLANLSSVDICFSSVTVPKALVNYMLGIKTISYTECMTQIYFFITFINMDGFLLSVMAYDRYVAICHPLHYTMMMRPRLCVLLVAISWAITNLHALLHTLLMVRLTFCSHNAMHHFFCDPYPILKLSCSDTFINDITAFTVGGLTSITPFTCITVSYGYILSNVLKFPSIQGIRKALSTCGSHLTVVSLFYGAILGVYMHPSSTYSV--QDMVATAFFTVVTPMVNPFIYS------------------LRNRDVKG-----------ALRKLMCRRLTSSRFYN----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15612-1", "uniprot_id": "OR1Q1_HUMAN", "id": "Q15612-1", "name": "Olfactory receptor 1Q1", "aln": "--------------------------------------------------MDNSNWTS----VSHFVLLGISTHPEEQIP-LFLVFSLMYAINISGNLAIITLILSAPR-LHIPMYIFLSNLALTDICFTSTTVPKMLQIIFSPTKVISYTGCLAQTYFFICFAVMENFILAVMAYDRYIAICHPFHYTMILTRMLCVKMVVMCHALSHLHAMLHTFLIGQLIFCADNRIPHFFCDLYALMKISCTSTYLNTLMIHTEGAVVISGALAFITASYACIILVVLRIPSAKGRWKTFSTCGSHLTVVAIFYGTLSWVYFRPLSSYSVT-KGRIITVVYTVVTPMLNPFIYS------------------LRNGDVKG-----------GFMKWMSRMQTFFFR------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGB8-1", "uniprot_id": "O4F15_HUMAN", "id": "Q8NGB8-1", "name": "Olfactory receptor 4F15", "aln": "--------------------------------------------------MNGMNHSV----VSEFVFMGLTNSREIQLL-LFVFSLLFYFASMMGNLVIVFTVTMDAH-LHSPMYFLLANLSIIDMAFCSITAPKMICDIFKKHKAISFRGCITQIFFSHALGGTEMVLLIAMAFDRYMAICKPLHYLTIMSPRMCLYFLATSSIIGLIHSLVQLVFVVDLPFCGPNIFDSFYCDLPRLLRLACTNTQELEFMVTVNSGLISVGSFVLLVISYI-FILFTVWKHSSGGLAKALSTLSAHVTVVILFFGPLMFFYTWPSPTSHL---DKYLAIFDAFITPFLNPVIYT------------------FRNKDMKV-----------AMRRLCSRLAHFTKIL-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGB9-1", "uniprot_id": "OR4F6_HUMAN", "id": "Q8NGB9-1", "name": "Olfactory receptor 4F6", "aln": "--------------------------------------------------MDEANHSV----VSEFVFLGLSDSRKIQLL-LFLFFSVFYVSSLMGNLLIVLTVTSDPR-LQSPMYFLLANLSIINLVFCSSTAPKMIYDLFRKHKTISFGGCVVQIFFIHAVGGTEMVLLIAMAFDRYVAICKPLHYLTIMNPQRCILFLVISWIIGIIHSVIQLAFVVDLLFCGPNELDSFFCDLPRFIKLACIETYTLGFMVTANSGFISLASFLILIISYI-FILVTVQKKSSGGIFKAFSMLSAHVIVVVLVFGPLIFFYIFPFPTSHL---DKFLAIFDAVITPVLNPVIYT------------------FRNKEMMV-----------AMRRRCSQFVNYSKIF-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH21-1", "uniprot_id": "OR4F5_HUMAN", "id": "Q8NH21-1", "name": "Olfactory receptor 4F5", "aln": "---------------------------------------------------------M----VTEFIFLGLSDSQELQTF-LFMLFFVFYGGIVFGNLLIVITVVSDSH-LHSPMYFLLANLSLIDLSLSSVTAPKMITDFFSQRKVISFKGCLVQIFLLHFFGGSEMVILIAMGFDRYIAICKPLHYTTIMCGNACVGIMAVTWGIGFLHSVSQLAFAVHLLFCGPNEVDSFYCDLPRVIKLACTDTYRLDIMVIANSGVLTVCSFVLLIISYT-IILMTIQHRPLDKSSKALSTLTAHITVVLLFFGPCVFIYAWPFPIKSL---DKFLAVFYSVITPLLNPIIYT------------------LRNKDMKT-----------AIRQLRKWDAHSSVKF-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGD3-1", "uniprot_id": "OR4K5_HUMAN", "id": "Q8NGD3-1", "name": "Olfactory receptor 4K5", "aln": "--------------------------------------------------MDKSNSSV----VSEFVLLGLCSSQKLQLF-YFCFFSVLYTVIVLGNLLIILTVTSDTS-LHSPMYFLLGNLSFVDICQASFATPKMIADFLSAHETISFSGCIAQIFFIHLFTGGEMVLLVSMAYDRYVAICKPLYYVVIMSRRTCTVLVMISWAVSLVHTLSQLSFTVNLPFCGPNVVDSFFCDLPRVTKLACLDSYIIEILIVVNSGILSLSTFSLLVSSYI-IILVTVWLKSSAAMAKAFSTLASHIAVVILFFGPCIFIYVWPFTISPL---DKFLAIFYTVFTPVLNPIIYT------------------LRNRDMKA-----------AVRKIVNHYLRPRRISEMSLVVRTSFH------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VET4-1", "uniprot_id": "Q8VET4_MOUSE", "id": "Q8VET4-1", "name": "Olfactory receptor", "aln": "--------------------------------------------------MDNTNYSV----VSEFVLLGLSSSRELQIF-YFVFFSMLYIVIILGNLLIIIAVTSDSS-LHSPMYFLLGNLSFFDICQASFATPKMIVDFLSEHKTISFSGCIAQIFFIHLFTGGEMVILVSMAYDRYVAICKPLHYMTIMNQTTCTALVVISWAVGLVHTLSQLSFTVKLSFCGPNEVDSFFCDLPRVVKLACIDSYITEILIVVNSGILSLSTFSLLVSSYV-IILVTVWFKSSAAMAKAFSTLAAHIMVVVLFFGPCIFIYVWPFTTYPV---DKILAIFYTVFTPILNPIIYT------------------LRNRDMKA-----------VMGKIAAHYLRPPKVAEMSFVARISLY------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NH42-1", "uniprot_id": "OR4KD_HUMAN", "id": "Q8NH42-1", "name": "Olfactory receptor 4K13", "aln": "--------------------------------------------------MERANHSV----VSEFILLGLSKSQNLQIL-FFLGFSVVFVGIVLGNLLILVTVTFDSL-LHTPMYFLLSNLSCIDMILASFATPKMIVDFLRERKTISWWGCYSQMFFMHLLGGSEMMLLVAMAIDRYVAICKPLHYMTIMSPRVLTGLLLSSYAVGFVHSSSQMAFMLTLPFCGPNVIDSFFCDLPLVIKLACKDTYILQLLVIADSGLLSLVCFLLLLVSYG-VIIFSVRYRAASRSSKAFSTLSAHITVVTLFFAPCVFIYVWPFSRYSV---DKILSVFYTIFTPLLNPIIYT------------------LRNQEVKA-----------AIKKRLCI-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGC6-1", "uniprot_id": "OR4KH_HUMAN", "id": "Q8NGC6-1", "name": "Olfactory receptor 4K17", "aln": "--------------------------------------------------MKLLNQSQ----VSEFILLGLTSSQDVEFL-LFALFSVIYVVTVLGNLLIIVTVFNTPN-LNTPMYFLLGNLSFVDMTLASFATPKVILNLLKKQKVISFAGCFTQIFLLHLLGGVEMVLLVSMAFDRYVAICKPLHYMTIMNKKVCVLLVVTSWLLGLLHSGFQIPFAVNLPFCGPNVVDSIFCDLPLVTKLACIDIYFVQVVIVANSGIISLSCFIILLISYS-LILITIKNHSPTGQSKARSTLTAHITVVILFFGPCIFIYIWPFGNHSV---DKFLAVFYTIITPILNPIIYT------------------LRNKEMKI-----------SMKKLWRAFVNSREDT-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGD2-1", "uniprot_id": "OR4K2_HUMAN", "id": "Q8NGD2-1", "name": "Olfactory receptor 4K2", "aln": "--------------------------------------------------MDVGNKST----MSEFVLLGLSNSWELQMF-FFMVFSLLYVATMVGNSLIVITVIVDPH-LHSPMYFLLTNLSIIDMSLASFATPKMITDYLTGHKTISFDGCLTQIFFLHLFTGTEIILLMAMSFDRYIAICKPLHYASVISPQVCVALVVASWIMGVMHSMSQVIFALTLPFCGPYEVDSFFCDLPVVFQLACVDTYVLGLFMISTSGIIALSCFIVLFNSYV-IVLVTVKHHSSRGSSKALSTCTAHFIVVFLFFGPCIFIYMWPLSSFLT---DKILSVFYTIFTPTLNPIIYT------------------LRNQEVKI-----------AMRKLKNRFLNFNKAMPS---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH43-1", "uniprot_id": "OR4L1_HUMAN", "id": "Q8NH43-1", "name": "Olfactory receptor 4L1", "aln": "--------------------------------------------------MDLKNGSL----VTEFILLGFFGRWELQIF-FFVTFSLIYGATVMGNILIMVTVTCRST-LHSPLYFLLGNLSFLDMCLSTATTPKMIIDLLTDHKTISVWGCVTQMFFMHFFGGAEMTLLIIMAFDRYVAICKPLHYRTIMSHKLLKGFAILSWIIGFLHSISQIVLTMNLPFCGHNVINNIFCDLPLVIKLACIETYTLELFVIADSGLLSFTCFILLLVSYI-VILVSVPKKSSHGLSKALSTLSAHIIVVTLFFGPCIFIYVWPFSSLAS---NKTLAVFYTVITPLLNPSIYT------------------LRNKKMQE-----------AIRKLRFQYVSSAQNF-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VGE7-1", "uniprot_id": "Q8VGE7_MOUSE", "id": "Q8VGE7-1", "name": "Olfactory receptor", "aln": "--------------------------------------------------MDGSNRSL----VSEFVLLGLARSQNLQVL-LFIIFLVVYLLILSGNTIVMFLIITDKN-LHSPMYFFLANLSFVDMWLSSATTPKMITDFLKEPKIISFAGCMSQVFFDHCVGAVEMLLLVVMAYDRYVAICKPLHYFTIMSLKRCAGLVLTSWAIAFVHAMSQLLAVVQLPLCGHMEIDSFFCDIPLIIKLACMDSHILDIYMNVDCGFVVVTCFILLLISYT-YILLTVRQSSKAGASKALSTCTAHITVVMIFFVPCIFIYVWPLSITWL---DKFLAVFYTVFAPLLNPAIYT------------------LRNKEMRN-----------AVKKLKNHFMDYKGNT-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGF9-1", "uniprot_id": "OR4X2_HUMAN", "id": "Q8NGF9-1", "name": "Olfactory receptor 4X2", "aln": "--------------------------------------------------------------MTEFIFLVLSPNQEVQRV-CFVIFLFLYTAIVLGNFLIVLTVMTSRS-LGSPMYFFLSYLSFMEICYSSATAPKLISDLLAERKVISWWGCMAQLFFLHFFGGTEIFLLTVMAYDHYVAICKPLSYTTIMNWQVCTVLVGIAWVGGFMHSFAQILLIFHLLFCGPNVINHYFCDLVPLLKLACSDTFLIGLLIVANGGTLSVISFGVLLASYM-VILLHLRTWSSEGWCKALSTCGSHFAVVILFFGPCVFNSLRPSTTLPI---DKMVAVFYTVITAILNPVIYS------------------LRNAEMRK-----------AMKRLWIRTLRLNEK------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH49-1", "uniprot_id": "OR4X1_HUMAN", "id": "Q8NH49-1", "name": "Olfactory receptor 4X1", "aln": "----------------------------------------------------MVATNN----VTEIIFVGFSQNWSEQRV-ISVMFLLMYTAVVLGNGLIVVTILASKV-LTSPMYFFLSYLSFVEICYCSVMAPKLIFDSFIKRKVISLKGCLTQMFSLHFFGGTEAFLLMVMAYDRYVAICKPLHYMAIMNQRMCGLLVRIAWGGGLLHSVGQTFLIFQLPFCGPNIMDHYFCDVHPVLELACADTFFISLLIITNGGSISVVSFFVLMASYL-IILHFLRSHNLEGQHKALSTCASHVTVVDLFFIPCSLVYIRPCVTLPA---DKIVAVFYTVVTPLLNPVIYS------------------FRNAEVKN-----------AMRRFIGGKVI----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGM1-1", "uniprot_id": "OR4CF_HUMAN", "id": "Q8NGM1-1", "name": "Olfactory receptor 4C15", "aln": "----------------------------------------------------MQNQSF----VTEFVLLGLSQNPNVQEI-VFVVFLFVYIATVGGNMLIVVTILSSPALLVSPMYFFLGFLSFLDACFSSVITPKMIVDSLYVTKTISFEGCMMQLFAEHFFAGVEVIVLTAMAYDRYVAICKPLHYSSIMNRRLCGILMGVAWTGGLLHSMIQILFTFQLPFCGPNVINHFMCDLYPLLELACTDTHIFGLMVVINSGFICIINFSLLLVSYA-VILLSLRTHSSEGRWKALSTCGSHIAVVILFFVPCIFVYTRPPSAFSL---DKMAAIFYIILNPLLNPLIYT------------------FRNKEVKQ-----------AMRRIWNRLMVVSDEKENIKL------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH37-1", "uniprot_id": "OR4C3_HUMAN", "id": "Q8NH37-1", "name": "Olfactory receptor 4C3", "aln": "----------------------------------------------------MDIPQN----ITEFFMLGLSQNSEVQRV-LFVVFLLIYVVTVCGNMLIVVTITSSPT-LASPVYFFLANLSFIDTFYSSSMAPKLIADSLYEGRTISYECCMAQLFGAHFLGGVEIILLTVMAYDRYVAICKPLHNTTIMTRHLCAMLVGVAWLGGFLHSLVQLLLVLWLPFCGPNVINHFACDLYPLLEVACTNTYVIGLLVVANSGLICLLNFLMLAASYI-VILYSLRSHSADGRCKALSTCGAHFIVVALFFVPCIFTYVHPFSTLPI---DKNMALFYGILTPMLNPLIYT------------------LRNEEVKN-----------AMRKLFTW-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH83-1", "uniprot_id": "OR4A5_HUMAN", "id": "Q8NH83-1", "name": "Olfactory receptor 4A5", "aln": "----------------------------------------------------MRQNNN----ITEFVLLGFSQDPGVQKA-LFVMFLLTYLVTVVGNLLIVVDIIASPS-LGSPMYFFLACLSFIDAAYSTTISPKLIVGLFCDKKTISFQGCMGQLFIDHFFGGAEVFLLVVMACDRYVAICKPLHYLTIMNRQVCFLLLVVAMIGGFVHSAFQIV-VYSLPFCGPNVIVHFSCDMHPLLELACTDTYFIGLTVVVNSGAICMVIFNLLLISYG-VILSSLKTYSQEKRGKALSTCSSGSTVVVLFFVPCIFIYVRPVSNFPT---DKFMTVFYTIITHMLSPLIYT------------------LRNSEMRN-----------AIEKLLGKKLTIF---IIGGVSVLM--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH70-1", "uniprot_id": "O4A16_HUMAN", "id": "Q8NH70-1", "name": "Olfactory receptor 4A16", "aln": "----------------------------------------------------MRPSSN----VTEFVLLGLTQDPDVKKT-LFVMFLLIYIVTMVGNLLIWVTTIGSPS-LGSLMYFFLAYLSLMDAIYSTAMSPKLMIDLLCDKIAISLSACMGQLFIEHLLGGAEVFLLVVMAYDRYVAISKPLHYLNIMNRLVCILLLVVAMIGGFVHSVVQIVFLYSLPICGPNVIDHSVCDMYPLLELLCLDTYFIGLTVVANGGIICMVIFTFLLISCG-VILNFLKTYSQEERHKALPTCISHIIVVALVFVPCIFMYVRPVSNFPF---DKLMTVFYSIITLMLNPLIYS------------------LRQSEMKN-----------AMKNLWCEKLSIVRKRVSPTLNIFIPSSKATNRR-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IF82-1", "uniprot_id": "O4A47_HUMAN", "id": "Q6IF82-1", "name": "Olfactory receptor 4A47", "aln": "----------------------------------------------------MEPRKN----VTDFVLLGFTQNPKEQKV-LFVMFLLFYILTMVGNLLIVVTVTVSET-LGSPMYFFLAGLSFIDIIYSSSISPRLISGLFFGNNSISFQSCMAQLFIEHIFGGSEVFLLLVMAYDCYVAICKPLHYLVIMRQWVCVVLLVVSWVGGFLHSVFQLSIIYGLPFCGPNVIDHFFCDMYPLLKLVCTDTHAIGLLVVANGGLACTIVFLLLLISYG-VILHSLKNLSQKGRQKALSTCSSHMTVVVFFFVPCIFMYARPARTFPI---DKSVSVFYTVITPMLNPLIYT------------------LRNSEMTS-----------AMKKLWRRDLISSST------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGN8-1", "uniprot_id": "OR4A4_HUMAN", "id": "Q8NGN8-1", "name": "Putative olfactory receptor 4A4", "aln": "----------------------------------------------------MEPRKN----VTDFVLLGFTQNPKEQKV-LFVMFLLFYILTMVGNLLIVVTVTVSET-LGSPMSFFLAGLTFIDIIYSSSISPRLISDLFFGNNSISFQSFMAQLFIEHLFGGSEVFLLLVMAYDRYVAICKPLHYLVIMRQWVCVLLLVVSWVGGFLQSVFQLSIIYGLPFCGPNVIDHFFCDMYPLLKLACTDTHVIGLLVVANGGLSCTIAFLLLLISYG-VILHSLKKLSQKGRQKAHSTCSSHITVVVFFFVPCIFMCARPARTFSI---DKSVSVFYTVITPMLNPLIYT------------------LRNSEMTS-----------AMKKL----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGL6-1", "uniprot_id": "O4A15_HUMAN", "id": "Q8NGL6-1", "name": "Olfactory receptor 4A15", "aln": "----------------------MELLTNNLKFITDPFVCRLRHLSPTPSEEHMKNKNN----VTEFILLGLTQNPEGQKV-LFVTFLLIYMVTIMGNLLIIVTIMASQS-LGSPMYFFLASLSFIDTVYSTAFAPKMIVDLLSEKKTISFQGCMAQLFMDHLFAGAEVILLVVMAYDRYMAICKPLHELITMNRRVCVLMLLAAWIGGFLHSLVQFLFIYQLPFCGPNVIDNFLCDLYPLLKLACTNTYVTGLSMIANGGAICAVTFFTILLSYG-VILHSLKTQSLEGKRKAFYTCASHVTVVILFFVPCIFLYARPNSTFPI---DKSMTVVLTFITPMLNPLIYT------------------LKNAEMKS-----------AMRKLWSKKVSLAGKWLYHS-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NHA9-1", "uniprot_id": "O4C46_HUMAN", "id": "A6NHA9-1", "name": "Olfactory receptor 4C46", "aln": "----------------------------------------------------MENRNN----MTEFVLLGLTENPKMQKI-IFVVFFVIYIITVVGYVLIVVTITASPS-LGSPMYLSLAYLSFIDACYSSVNTPNLITHSLYGKKAILFNGCMTQVFGEHFFGGAEGILLTVMAYDHYVAICKPLHYMTIMNQCVCALLMGVVWMGGFLHATIQILFIFQLPFCGPNVIDHFMCDLNPLLNLACTDTHMLELFIAANSGFICLLNFALLLVSYV-VILCSLRTHSLEARHKALSTCVSHITVVILFFVPCIFVYMRPAATLPI---DKAVAIFYTMITPMLNPLIYT------------------LKNAQMKN-----------AIRKLCSRKDISGDK------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGP0-1", "uniprot_id": "OR4CD_HUMAN", "id": "Q8NGP0-1", "name": "Olfactory receptor 4C13", "aln": "----------------------------------------------------MANRNN----VTEFILLGLTENPKMQKI-IFVVFSVIYINAMIGNVLIVVTITASPS-LRSPMYFFLAYLSFIDACYSSVNTPKLITDSLYENKTILFNGCMTQVFGEHFFRGVEVILLTVMAYDHYVAICKPLHYTTVMKQHVCSLLVGVSWVGGFLHATIQILFICQLPFCGPNVIDHFMCDLYTLINLACTNTHTLGLFIAANSGFICLLNCLLLLVSCV-VILYSLKTHSLEARHEALSTCVSHITVVILSFIPCIFVYMRPPATLPI---DKAVAVFYTMITSMLNPLIYT------------------LRNAQMKN-----------AIRKLCSRKAISSVK------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96R67-1", "uniprot_id": "OR4CC_HUMAN", "id": "Q96R67-1", "name": "Olfactory receptor 4C12", "aln": "----------------------------------------------------MEKKKN----VTEFILIGLTQNPIMEKV-TFVVFLVLYMITLSGNLLIVVTITTSQA-LSSPMYFFLTHLSLIDTVYSSSSAPKLIVDSFQEKKIISFNGCMAQAYAEHIFGATEIILLTVMACDCYVAICKPLNYTTIMSHSLCILLVAVAWVGGFLHATIQILFTVWLPFCGPNVIGHFMCDLYPLLKLVCIDTHTLGLFVAVNSGFICLLNFLILVVSYV-IILRSLKNNSLEGRCKALSTCISHIIVVVLFFVPCIFVYLRSVTTLPI---DKAVAVFYTMVVPMLNPVVYT------------------LRNAEVKS-----------AIRKLWRKKVTSDND------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH72-1", "uniprot_id": "OR4C6_HUMAN", "id": "Q8NH72-1", "name": "Olfactory receptor 4C6", "aln": "----------------------------------------------------MENQNN----VTEFILLGLTENLELWKI-FSAVFLVMYVATVLENLLIVVTIITSQS-LRSPMYFFLTFLSLLDVMFSSVVAPKVIVDTLSKSTTISLKGCLTQLFVEHFFGGVGIILLTVMAYDRYVAICKPLHYTIIMSPRVCCLMVGGAWVGGFMHAMIQLLFMYQIPFCGPNIIDHFICDLFQLLTLACTDTHILGLLVTLNSGMMCVAIFLILIASYT-VILCSLKSYSSKGRHKALSTCSSHLTVVVLFFVPCIFLYMRPVVTHPI---DKAMAVSDSIITPMLNPLIYT------------------LRNAEVKS-----------AMKKLW--MKWEALAGK----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGB2-1", "uniprot_id": "OR4C5_HUMAN", "id": "Q8NGB2-1", "name": "Olfactory receptor 4C5", "aln": "-----------------------------MYVSNCNPCAIHRKINYPNTKLDFEQVNN----ITEFILLGLTQNAEAQKL-LFAVFTLIYFLTMVDNLIIVVTITTSPA-LDSPVYFFLSFFSFIDGCSSSTMAPKMIFDLLTEKKTISFSGCMTQLFVEHFFGGVEIILLVVMAYDCYVAICKPLYYLITMNRQVCGLLVAMAWVGGFLHALIQMLLIVWLPFCGPNVIDHFICDLFPLLKLSCTDTHVFGLFVAANSGLMCMLIFSILITSYV-LILCSQR--------KALSTCAFHITVVVLFFVPCILVYLRPMITFPI---DKAVSVFYTVVTPMLNPLIYT------------------LRNTEVKN-----------AMKQLWSQIIWGNNLCD----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IEV9-1", "uniprot_id": "OR4CB_HUMAN", "id": "Q6IEV9-1", "name": "Olfactory receptor 4C11", "aln": "----------------------------------------------------MQQNNS----VPEFILLGLTQDPLRQKI-VFVIFLIFYMGTVVGNMLIIVTIKSSRT-LGSPMYFFLFYLSFADSCFSTSTAPRLIVDALSEKKIITYNECMTQVFALHLFGCMEIFVLILMAVDRYVAICKPLRYPTIMSQQVCIILIVLAWIGSLIHSTAQIILALRLPFCGPYLIDHYCCDLQPLLKLACMDTYMINLLLVSNSGAICSSSFMILIISYI-VILHSLRNHSAKGKKKALSACTSHIIVVILFFGPCIFIYTRPPTTFPM---DKMVAVFYTIGTPFLNPLIYT------------------LRNAEVKN-----------AMRKLWHGKIISENKG-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGL7-1", "uniprot_id": "OR4P4_HUMAN", "id": "Q8NGL7-1", "name": "Olfactory receptor 4P4", "aln": "----------------------------------------------------MEKSNN----STLFILLGFSQNKNIEVL-CFVLFLFCYIAIWMGNLLIMISITCTQL-IHQPMYFFLNYLSLSDLCYTSTVTPKLMVDLLAERKTISYNNCMIQLFTTHFFGGIEIFILTGMAYDRYVAICKPLHYTIIMSRQKCNTIIIVCCTGGFIHSASQFLLTIFVPFCGPNEIDHYFCDVYPLLKLACSNIHMIGLLVIANSGLIALVTFVVLLLSYV-FILYTIRAYSAERRSKALATCSSHVIVVVLFFAPALFIYIRPVTTFSE---DKVFALFYTIIAPMFNPLIYT------------------LRNTEMKN-----------AMRKVWCCQILLKRNQLF---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGB4-1", "uniprot_id": "OR4S1_HUMAN", "id": "Q8NGB4-1", "name": "Olfactory receptor 4S1", "aln": "----------------------------------------------------MGAKNN----VTEFVLFGLFESREMQHT-CFVVFFLFHVLTVLGNLLVIITINARKT-LKSPMYFFLSQLSFADICYPSTTIPKMIADTFVEHKIISFNGCMTQLFSAHFFGGTEIFLLTAMAYDRYVAICRPLHYTAIMDCRKCGLLAGASWLAGFLHSILQTLLTVQLPFCGPNEIDNFFCDVHPLLKLACADTYMVGLIVVANSGMISLASFFILIISYV-IILLNLRSQSSEDRRKAVSTCGSHVITVLLVLMPPMFMYIRPSTTLAA---DKLIILFNIVMPPLLNPLIYT------------------LRNNDVKN-----------AMRKLFRVKRSLGEK------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q15615-1", "uniprot_id": "OR4D1_HUMAN", "id": "Q15615-1", "name": "Olfactory receptor 4D1", "aln": "--------------------------------------------------MEPQNTTQ----VSMFVLLGFSQTQELQKF-LFLLFLLVYVTTIVGNLLIMVTVTFDCR-LHTPMYFLLRNLALIDLCYSTVTSPKMLVDFLHETKTISYQGCMAQIFFFHLLGGGTVFFLSVMAYDRYIAISQPLRYVTIMNTQLCVGLVVAAWVGGFVHSIVQLALILPLPFCGPNILDNFYCDVPQVLRLACTDTSLLEFLMISNSGLLVIIWFLLLLISYT-VILVMLRSHSGKARRKAASTCTTHIIVVSMIFIPCIYIYTWPFTPFLM---DKAVSISYTVMTPMLNPMIYT------------------LRNQDMKA-----------AMRRLGKCLVICRE-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGJ1-1", "uniprot_id": "OR4D6_HUMAN", "id": "Q8NGJ1-1", "name": "Olfactory receptor 4D6", "aln": "--------------------------------------------------MDQINHTN----VKEFFFLELTRSRELEFF-LFVVFFAVYVATVLGNALIVVTITCESR-LHTPMYFLLRNKSVLDIVFSSITVPKFLVDLLSDRKTISYNDCMAQIFFFHFAGGADIFFLSVMAYDRYLAIAKPLHYVTMMRKEVWVALVVASWVSGGLHSIIQVILMLPFPFCGPNTLDAFYCYVLQVVKLACTDTFALELFMISNNGLVTLLWFLLLLGSYT-VILVMLRSHSGEGRNKALSTCTSHMLVVTLHFVPCVYIYCRPFMTLPM---DTTISINNTVITPMLNPIIYS------------------LRNQEMKS-----------AMQRLQRRLGPSESRKWG---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8YED5-1", "uniprot_id": "O5BS1_HUMAN", "id": "A0A2R8YED5-1", "name": "Olfactory receptor 5BS1", "aln": "--------------------------------------------------MEVSNMTT----VTVFILLGLSNNPQVQAL-LFVLFLVIYLLTLLGNLLMVLVISTDSH-LCTPMYFFLRQLSFLDAFYSSIIVPKLLENLLSKGETISFLECFTQISLVIFSGATEACLLSVMAYDRFQAMCHPLLYVVIINRRVCAGLVGASWAIGMGTGLINTLLLAQQHFCGPNVIHSFACELPPVLLLTCSDPCASIVSILTTMSVLGLGTLVLLLGSYSCIIMTALRINSATGRSKIFSTCSSHFLVVTIFYTSGVLRYMIPASGSAL---EQVLSVQYSVITPLLNPLIYS------------------LKSQEVK-----------VALRRMLARKSR----------------LPL---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NH09-1", "uniprot_id": "OR8S1_HUMAN", "id": "Q8NH09-1", "name": "Olfactory receptor 8S1", "aln": "--------------------------------------------------MALGNHST----ITEFLLLGLSADPNIRAL-LFVLFLGIYLLTIMENLMLLLMIRADSC-LHKPMYFFLSHLSFVDLCFSSVIVPKMLENLLSQRKTISVEGCLAQVFFVFVTAGTEACLLSGMAYDRHAAICRPLLYGQIMGKQLYMHLVWGSWGLGFLDALINVLLAVNMVFCEAKIIHHYSYEMPSLLPLSCSDISRSLIALLCSTLLHGLGNFLLVFLSYTRIISTILSISSTSGRSKAFSTCSAHLTAVTLYYGSGLLRHLMPNSGSPI---ELIFSVQYTVVTPMLNSLIYS------------------LKNKEVKGERSLRDSSHLPQLHKGQARWKRPAFTEGRREPGHPELSIPVTPQPQGACACSALRAAPTALP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGX8-1", "uniprot_id": "OR6Y1_HUMAN", "id": "Q8NGX8-1", "name": "Olfactory receptor 6Y1", "aln": "---------------------------------------------MTTIILEVDNHTV----TTRFILLGFPTRPAFQLL-FFSIFLATYLLTLLENLLIILAIHSDGQ-LHKPMYFFLSHLSFLEMWYVTVISPKMLVDFLSHDKSISFNGCMTQLYFFVTFVCTEYILLAIMAFDRYVAICNPLRYPVIMTNQLCGTLAGGCWFCGLMTAMIKMVFIAQLHYCGMPQINHYFCDISPLLNVSCEDASQAEMVDFFLALMVIAIPLCVVVASYAAILATILRIPSAQGRQKAFSTCASHLTVVILFYSMTLFTYARPKLMYAYN-SNKVVSVLYTVIVPLLNPIIYC------------------LRNHEVKA-----------ALRKTIHCRGSGPQGNGAFSS------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NND4-1", "uniprot_id": "O2AT4_HUMAN", "id": "A6NND4-1", "name": "Olfactory receptor 2AT4", "aln": "--------------------------------------------------MDATACNESVDGSPVFYLLGIPSLPETFFLPVFFIFLLFYLLILMGNALILVAVVAEPS-LHKPMYFFLINLSTLDILFTTTTVPKMLSLFLLGDRFLSFSSCLLQMYLFQSFTCSEAFILVVMAYDRYVAICHPLHYPVLMNPQTNATLAASAWLTALLLPIPAVVRTSQMAYNSIAYIYHCFCDHLAVVQASCSDTTPQTLMGFCIAMVVSFLPLLLVLLSYVHILASVLRISSLEGRAKAFSTCSSHLLVVGTYYSSIAIAYVAYRADLPLD-FHIMGNVVYAILTPILNPLIYT------------------LRNRDVKA-----------AITKIMSQDPGCDRSI-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I8Z5-1", "uniprot_id": "Q9I8Z5_DANRE", "id": "Q9I8Z5-1", "name": "Olfactory receptor", "aln": "-----------------MYCFTLKSNACVNVNASIASILYASVFKLGSSSVMMAYYTN----ITEFYLLGFPGLHPEYYGAVGFLLLFVYLTLAGGNIFIISFIAYEKS-LQKPTYLIFCNLAVCDIAIGTVTLPKAIAKYFFDSSEITFLSCFVQMFFVHYLGSINSFLMLLMAVDRFVAVCNPLRYCVLITNKTILLACALIWMLCISWLTFMVYNTFDEPYCGSNIITQNYCDHNSIIKLSCGDIGQKKFYSFSFAMFVLLGPLIFIIFSFTAIIISVFRISDTQARFKTFSTCTPQLLIICLYYVPRCVVYVHDVTIAISPGIRVMLIMWYTLIPPIVNPMIYC------------------FRTKEIKD-----------AIKKKLKDRKVNVQI------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . : : : : . * : : : : *. : . .: . . : : : . ", "identical_positions": 2, "similar_positions": 24, "identity": "0.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010309-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VF29-1", "uniprot_id": "Q8VF29_MOUSE", "id": "Q8VF29-1", "name": "Olfactory receptor", "aln": "----------------------MDQI--------------NETVAFEFVLLGLSSSWKNTIFLMSTFSLLYVSIIVGNLFIVFLVINDSRL-QSPMYFLLANLSLIDVGLSSTTVPKMISDLLKEHKV--ISFHSCMTQICSIHIMGGVEMVLLIAMAFDRYTAICKPLHYMSIMSPRICISFVIAGWVTGVVHAMSQFSFVVNLPFCGPNKVDSFYCDFPRIIQLACTDRDTFEFVVAANS-GFMTLGTFFLLLLSYVFILVTVWQRSSGDL--SKALVTLSAHITVVVLFFTPCMFLYVWP--FPTSSTDKYLFIVDFAVTPALNPVIYTLRNKDMKEAIK---------KLSKQRCYIRIF-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TQY0-1", "uniprot_id": "Q7TQY0_MOUSE", "id": "Q7TQY0-1", "name": "Olfactory receptor", "aln": "----------------------MDQV--------------NASALPEFVLLGLAQSFGTQIFFGLFFSLFYVGILFGNLFIVFIVIVDSHL-HFPMYILLANLSLIDLGLSSTTIPRTISDLFTGCKV--ISFHSCMTQMFFIHVMGGVEMVLLIAMAYDRYIAICKPLHYLMIMNPKKCIILVIAAWVIGMIHAVSQFLFVVNLPFCGPYNVGSFYCDFPRVIKLACMDTYKLEFVVSANS-GFISMCTFFFLITSYIFILASVRQHSSTDL--SKAFVTLSAHITVVVLFFIPCMFLYVWP--FPTKSLDNFFAIVDFVLTPVLNPTIYTLRNKDMRLAIR---------RLSRQVLSSREFI----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VET0-1", "uniprot_id": "Q8VET0_MOUSE", "id": "Q8VET0-1", "name": "Olfactory receptor", "aln": "----------------------MDKA--------------NHSVVSEFVFLGLSNRWGIQLLLFLFSSMFYIASVMGNLLIVFSVTADSNL-HSPMYFLLANLSFLDLGVCSIAAPKMIFDLFRKHKA--ISFGGCITQIFFIHAIGGTEMVLLIAMAFDRYVAICKPLHYLTIMRPQICILILAVSWVLGLIHSVAQLAFVVDLPFCGPNILDSFYCDLPQLIKLACTETSKLVFMVTANS-GLISVGSFFILIISYIFILVTVRKHSSGSI--AKALSTLSAHVTVVVLFFGPLIFFYTWP--FPSSHLDKFLAIFDAVLTPFLNPVIYTFRNKEMKAAMR---------KLCSQLVNYRKVS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VF85-1", "uniprot_id": "Q8VF85_MOUSE", "id": "Q8VF85-1", "name": "Olfactory receptor", "aln": "----------------------MGEA--------------NCSVVSEFVFLGLSNSWAIQLFLFFFSCIFYVASLLGNFLIVLTVTSDPQL-QSPMYFLLGNLSIIDLIFCSSTTPKMIYDLFRRHKT--ISFGGCITQIFFIHAVGGTEMVLLIAMAFDRYVAICKPLHYLTIMSPQKCILILVASWIIGFIHSVTQLSFVVDLPFCGPNELDSFFCDLPRFIKLACVDTYTLGFMVTANS-GFISVASFLILIISYIFILVTVQKKSLGSL--GKALSTLSAHVIVVVLFFGPLIFFYTWP--FPTSHLDKFLAIFDAVITPFLNPVIYTLRNKEMKVAMR---------RLCSQFVNYNKIS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VG12-1", "uniprot_id": "Q8VG12_MOUSE", "id": "Q8VG12-1", "name": "Olfactory receptor", "aln": "--------------------MLMGGA--------------NLSVVSEFVFLGLTNSWDIQLLLFVFSSVFYVASMMGNSLIIFTVASDPHL-HTPMYFLLANLSFIDLGVSSVTSPKMIYDLFRKHKV--ISFTGCVIQIFSIHVIGGVEMVLLIAMAFDRYVAICKPLHYLTILSPRMCLFFVVIAWIVGLIHSLAQLVFVINLPFCGPNVLDSFYCDLPRFIKLACVDTHKLEFMVTANS-GFISVGSFFILIVSYIVIIISVQKHSSGGF--SKALSTLSAHISVVVLFFGPLIFVYTWP--TPSVHLDKFLAIFDAVITPFLNPVIYTFRNQEMKMAMK---------RVFKQLLSYRKIS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2AVW1-1", "uniprot_id": "A2AVW1_MOUSE", "id": "A2AVW1-1", "name": "Olfactory receptor", "aln": "----------------------MDGE--------------NHTVVSEFVFLGLTHSWEIQLLLLVLSSVLYILSMAGNILIVFSVTIDPHL-HSPMYFLLACLSFIDLVACSVTSPKMVYDLFRKHKV--ISFGGCITQIFFIHLVGGVEMVLLVAMAFDRYIAICKPLHYLTIMSPRVCVLFLGAAWGLGISHSLFQLAFLIDLPFCGPNILDSFYCDLPKLLRLACKDTYKLQFMVTINS-GFICVGSFLLLLISYIFILFSVWKHSSGGS--SKALSTLSAHITVVFLFFGPTLFIYTWP--HPNSQIDKFLALFDAVLTPFLNPVIYTFRNKEMKVVIR---------RVFKTLLTFRGIS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A288CFY5-1", "uniprot_id": "A0A288CFY5_MOUSE", "id": "A0A288CFY5-1", "name": "Olfactory receptor", "aln": "----------------------MKEASAETLFWNQSTWETNHSVVTEFILMGLSNSRELQIFLFAFFFVFYVGIVFGNLLIVITVTNDSHL-HSPMYFLLANLSFIDLCVSSVTAPKTIADFFYKRKV--ISVKGCFTQIFLLHFFGGSEMVTLVAMAFDRYVAICKPLSYTTVMRGNVCVSIVATAWAIGFLHSVSQLAFAISLPFCGPNRVDSFYCDLPRVIKLACAETYRLDIMVIANS-GVLSVCSFVLLIISYGIILMTIQRRPSDRS--SKALSTLTAHITVVLLFFGPCIFIYAWP--FPIKSLDKFLAVFYSVVTPLLNPIIYTLRNTEMKTAMR---------RLRQWNLSFWVKS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1L1SVB5-1", "uniprot_id": "A0A1L1SVB5_MOUSE", "id": "A0A1L1SVB5-1", "name": "Olfactory receptor", "aln": "----------------------MKEANTETLFWNESSREANDSVVKEFIFIGLSDSQGLQIFLFAFFLIFYVGIVFGNLLIVMTVTYDSHL-HSPMYFLLANLSFIDLCLSSVTAPKMIADFFRKHKV--ISVHGCFAQIFLLHFFGGSELVTLIAMAFDRYVAICKPLRYTIIMRGNVCAGIVATAWATGFLHSVSQLAFAVNLPFCGPNKVDSFYCDLPRVIKLACADTYRLDIMVIANS-GVLTVCSFVLLIISYSIILTTIQRRPSDRS--SKALSTLTAHITVVLLFFGPCIFIYAWP--FPIKSLDKFLAVFYSVVTPLLNPIIYTLRNTEMKTAMR---------RLRQWNLNFWVNS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PZU2-1", "uniprot_id": "E9PZU2_MOUSE", "id": "E9PZU2-1", "name": "Olfactory receptor", "aln": "----------------------MDYE--------------NGSAVTEFILVGFSGNWQLQIFFFVTFTLIYGATVVGNILIIVTVAANSAL-HSPMYFLLGNLSFLDMCLSTVTTPKMISDLLAAHKS--ISFQGCMAQMFFMHFFGGAEMTLLIVMAFDRYVAICKPLHYRIIMSHKLLNRFIILSWTIGFIHTMSQMALTVNLPFCGHNIINNIFCDLPLVIKLACIETYTLELFVIADS-GLLSFISFFLLLVSYTVILLIVKHKSPGSL--SKALSTLSAHIIVVTLFFGPCIFIYAWP--FGSFASNTTLAVFYTVITPLLNPIIYTLRNQEMKKAMR---------KLWIQQVSCT-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "K7N5X7-1", "uniprot_id": "K7N5X7_MOUSE", "id": "K7N5X7-1", "name": "Olfactory receptor", "aln": "----------------------MDYK--------------NGSAVTEFILVGFSGNWQLQIFFFVTFTLIYGATVVGNILIIVTVAANSAL-HSPMYFLLGNLSFLDMCLSTVTTPKMISDLLAAHKS--ISFQGCMVQMFFSHFLGGAEMTLLIVMAFDRYVAICKPLHYRIIMSHRLLNRFIILSWTIGFIHTMSQMALTVNLPFCGHNIINNIFCDLPLVIKLACIETYTLELFVIADS-GLLSFISFFLLLVSYTVILLIVKHKSPGSL--SKALSTLSAHIIVVTLFFGPCIFIYAWP--FGSFASNTTLAVFYTVITPLLNPIIYTLRNQEMKKAMR---------KLWNQQVSCR-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFT5-1", "uniprot_id": "Q8VFT5_MOUSE", "id": "Q8VFT5-1", "name": "Olfactory receptor", "aln": "----------------------METE--------------NRTVVTEFILIGLTQSHDIQRLVFVLSLIFYIIILPGNILIILTIRSDPGL-TAPLYFFLGNLAFLDASYSFIVAPRMLVDFFSEKKI--ISYKACITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHYSTVMSPRACYVMLLALWLGGFIHSIIQVVLILRLPFCGPNHLDNFFCDVPQVIKLACTDTFAVELLMIFNS-GLLTLLCFLGLLTSYAVILCHVHRSASEGK--NKAISTCTTHVIIIFIMFGPAIFIYTRP--FTALSADKVVSFFHTVIFPLMNPVIYTLRNQEVKTSMK---------KLIIRHIIC--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFC8-1", "uniprot_id": "Q8VFC8_MOUSE", "id": "Q8VFC8-1", "name": "Olfactory receptor", "aln": "----------------------MEIK--------------NSSVVTEFILLGLTQSQEAQLLVFALISVFYLIILPGNFLIIFTIRSDSGL-TAPLYFFLGNLAFLDASYSFIVAPRMLVDFFCEKKV--ISYKACITQLFFLHFLGAGEMFLLVVMAVDRYIAICRPLYYSTLMNPRVCYALLLALWLGGFAHSIVQVALILNLPFCGPNQLDNFFCDVPQVVKLACTDTFAVELLMVSNS-GLLTLLCFLGLLASYAVILYHVKGHSSEGK--SKAISTCTTHIIIVFLMFGPAIFIYTRP--FQALQADKVVSLFHTVIFPLMNPVIYTLRNQEVKTSMR---------KLLSQYVIC--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFT4-1", "uniprot_id": "OR4M1_MOUSE", "id": "Q8VFT4-1", "name": "Olfactory receptor 4M1", "aln": "----------------------MEPA--------------NDTTVTEFILTGLSQTREVQLVLFVIFLSFYLFILPVNILIICTIRLDSHL-SSPMYFLLANLAFLDIWYSSITAPKMLVDFFVERKI--ISFGGCIAQLFFLHFVGASEMFLLTVMAFDRYAAICRPLHYATIMNRRLCCILVALSWTGGFVHSIIQVALIVRLPFCGPNELDNYFCDITQVVRIACANTFLEEMVMIFSS-GLISVVCFIALLMSYAFLLTMLKKHSSSGESTSRAISTCYSHITIVVLMFGPSIYIYARP--FDSFSLDKVVSVFHTVIFPLLNPIIYTLRNKEVKAAMR---------KLVNRYIFCKEK-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFU9-1", "uniprot_id": "Q8VFU9_MOUSE", "id": "Q8VFU9-1", "name": "Olfactory receptor", "aln": "----------------------MELG--------------NHTKVTEFIFCGLTQSQELSLLLFFFLSIVYITTVLVNVTIMVTVTWESRL-HTPMYFLLRNLSVLDICFSSITVPKVLVDLLSRRKT--ISFNGCFTQIFFFHLLGGADIFSLSVMAFDRYMAIFRPLHYVTIMSRGRCTALIAASWVGGFVHSIVQIFLLLPLPFCGPNVVDSFYCDVPQVLKLACTDTFVLELLMISNN-GLITTLWFVLLLVSYTVILTMLRSHTGEGR--KKAISTCTSHITVVTLHFVPCIYVYARP--FTALPMDRAVSITLNIIVPVLNPMIYTLRNQEMKSAMK---------RLRKRLILSEVE-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2AUS6-1", "uniprot_id": "A2AUS6_MOUSE", "id": "A2AUS6-1", "name": "Olfactory receptor", "aln": "----------------------MEST----------------NNITEFILLGLSQNKKIKALCFLMFLFCYIAILGGNMIILISITCSQLI-EQPMYFFLNYLALSDLCYTSTVTPKFLTDLLVERNK--ISYTSCMAQLFTMHFFGGIEILILTVMAYDRYVAICKPLHYSIIMSRGRCHAMVTACCAGAFIHSFLQSLLAISLPFCGHNEMDHYFCDIYPLLTLSCTNTHRVGLLVVANS-GMMGLVTFVVLMWSYYFILYTIRAYPAESR--SKALSTCSSHVTVVIFFFVPVLFIYIRP--ATTYPEDKVFALFYTILAPMFNPLIYTLRNTEMKNALR---------KVWCHKLFFI-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VG47-1", "uniprot_id": "Q8VG47_MOUSE", "id": "Q8VG47-1", "name": "Olfactory receptor", "aln": "-----------------------MGY----------------GNLTEFILLGLFHNEDVKAICAVLFLLCYLAILCGNLVVLLTIKGSQLS-EQPMYFFLSYLSFMDVCFTSTVAPKFIIGLLVQCNT--ISYNGCIAQMFYAHFFGATEIFILVVMAYDRYVAICRPLYYMITMSRQVCYILVIGSVFGAFIHSLVHVLVIIRLPFCGSNEIDHYFCDIFPLLKLACTDTRLLVIVIITTT-GVMSILTFVALVISYIIILSILRTRSSESR--RKALSTCGSHITVVFMFFLPLIFTYVPM--GDSVGDDKVFALFYTMIAPLFNPLIYTLRNTDMKNAMR---------KVWCQDKLFEGK-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGG1-1", "uniprot_id": "Q8VGG1_MOUSE", "id": "Q8VGG1-1", "name": "Olfactory receptor", "aln": "----------------------MQNQ----------------SFVTEFILLGLSQNLNVEKMLFVLFLFIYIATIGGNMMIVVTIIYSPALLGSPMYFFLAFLSFLDACTSSTVTPKIIVDCFYERKT--ISFECCMTQLFTVHFFTGAEVIVLASMAYDRYVAICKPLHYSSIMTQRLCGILVVVSWAGGFLHSIIQIIFTLQLPLCGPNVIDHYMCDLFPLLKLACTDTHIYVLLIFANS-GAICIIIFSLLIVSYGVILFSLRAQSSEGR--RKALSTCGSHITVVLLFFVPCILIYARP--TSAFSFEKNMLIFVNVLTPLLNPMVYTFRNKEMINAIK---------KIWKRF-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "L7MU54-1", "uniprot_id": "L7MU54_MOUSE", "id": "L7MU54-1", "name": "Olfactory receptor", "aln": "----------------------MQNQ----------------SFVTEFIILGLSQNPIVEKILFFVLLLVYLATIGGNIIIVVTIMYSPALLGSPMYFFLAFLSFLDLCVSSTVIPKMIVDFFYEKKT--ISFGCCMMQLFSVHFFSGTEMIVLAAMAYDRYVAICKPLHYFSILTRRLCSILVAISWAGGFLHSIIQVIFTLQLPLCGPNVIDHYTCDLFPLLKLACTDTHIFVLLVFANS-GAICIIIFSLLLVSYGVILFSLRAHSSEGR--RKALSTCGAHVTVVVLFLVPCILIYARD--TSAFSFEKHTLLFVNVLTPLLNPTVYTFRNKEMINAIR---------KMCKRLKMIFVRF----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1L1SU13-1", "uniprot_id": "A0A1L1SU13_MOUSE", "id": "A0A1L1SU13-1", "name": "Olfactory receptor", "aln": "----------------------MLNQ----------------SFVTEFILLGLSQNPKVEKILFVLFFLVYLATIGGNIVIVVTILFSPALFGSPMYFFLSFLSFLDACISSVITPKMIVDFFYETKT--ISFECCMVQLFAVHFFTGVEVIVLSAMAYDRYVAICKPLHYSSIMNQRLCVILVGIAWAGGFLHSITQIIFTLQLPFCGPNVIEHFICDLFPLLKLACTNTHIFVILVFANS-GSICIIIFSLLLVSYGVILFSLRSHSSEGR--SKALSTCGSHITVVLLFFVPCILIYARN--TSAFSFEKNVFIFADVLTPLLNPMVYTFRNKEMKNAIK---------KIWRRLFNISDKH----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A3KGY4-1", "uniprot_id": "A3KGY4_MOUSE", "id": "A3KGY4-1", "name": "Olfactory receptor", "aln": "----------------------MQNQ----------------SIVTEFILLGLSQNPKVEKILSVLFFLVYLATIGGNIIIVVTIVFSPALSGSPMYFFLSFLSFLDACVSSVITPKMIVDFFYERKT--ISFECCMIQLFAVHFFTGVEVIVLSAMAYDRYVAICKPLHYSSIMTQRLCGILVGIAWAGGFLHSIIQIIFTLQLPFCGPNVIDHFVCDLFPLLKLACTNTHIFVILVFANS-GSICIIIFSILLVSYGVILFSLRNHSSEGR--RKALSTCGSHITVVLLFFVPCILIYARN--NSEFSFEKNVFIFDDVLTPMLNPLAYTFRNKEMKNAIK---------KMWRRLFNISDKH----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TQZ9-1", "uniprot_id": "Q7TQZ9_MOUSE", "id": "Q7TQZ9-1", "name": "Olfactory receptor", "aln": "----------------------MQNQ----------------SFITEFVFLGLSQNPNVQKIIFVICLLVYIATIGGNMMIVVTVVSTPALLGSPMYFFLAFLSLLDASFSSAMTPKMIVDSLYERKT--ISFEGCMIQLFAEHFFGGAEVIVLSAMAYDRYVAICKPLHYSSIMTLRLCGTLVGVAWTGGFLHSIIQIIFTLQLPFCGPNIIDHFICDLYPLLELACTDTHIFGLLVVANS-GFICIIIFTLLLVSYGFILLSLRSHSSEGR--WKALSTCGSHIAVVVLFFVPCIFTYARP--PTAFSFDKMVAIFYTMLSPLLNPMIYTFRNKDMKNAIR---------KMWTRLIVHSDKK----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VEX7-1", "uniprot_id": "Q8VEX7_MOUSE", "id": "Q8VEX7-1", "name": "Olfactory receptor", "aln": "----------------------MQNQ----------------SFVTEFVFLGLSQNPNLQKLIFIICLVVYIATMGSNMMIVVTVVCSPTLLGSPMYFFLAFLSLLDASFSSAMTPKMILDSLYKRKT--ISFEGCMIQLFVEHFLGGAEMILLTAMAYDRYVAICKPLHYSSIMTRKVCGTLVGVAWAGGLLHSTVQIIFTLQLPFCGPNVINHFMCDLFPLLELACTDTHIFGLFVVANS-GLICIIVFVLLLVSYGFILLSLRSQSSEGR--WKALSTCGSHVAVVVLFFVPCIFIYARP--HSAFSFDKMVALFYTMLSPLLNPIIYTFRNKDMKNAIR---------KLWKKLVMVSDER----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGM6-1", "uniprot_id": "Q8VGM6_MOUSE", "id": "Q8VGM6-1", "name": "Olfactory receptor", "aln": "----------------------MGQN----------------HNVTEFIFVGLSQDPAGQKVLFVLFSLTYIVTMFGNLLIALTVIASPSL-NSPMYFFLACLSVLDALYCNTISPNLIIDLLYNKKN--ISFRACMLQLFVEHLFGGVEVFLLVFMAYDRYVAICKPLHYLTIMNQRVCILLLLIAGVGGILHSLIQVLTVYKLPFCGPNVIDHFMCDMNQLLGLACTDTYFLGITVMANG-GVICVGIFTFLLVSYGIILNSLKTHSREGR--HKALFTCSSHIMVVVCFFAPCSFIYARP--VSNFPVDKYIAVFYTVVSPMLNPLIYTLRNSEMKNSIK---------KLWCKTLTT--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGM7-1", "uniprot_id": "Q8VGM7_MOUSE", "id": "Q8VGM7-1", "name": "Olfactory receptor", "aln": "----------------------MGQS----------------YNVTEFIFVDLTQDPAGKKALFVLFSLTYIVTMLGNLLIAVTVIASPSL-NSPMYFFLACLSVLDAFYCNTISPNLIIGLLKDKNN--ISFRACMLQLFVEHLFGGVEVFLLVFMAYDRYVAICKPLHYLTIMNQRVCILLLLVAGVGGILHSLIQVLTVYKLPFCGPNVIDHFMCDMNPLLGLACTDTYFLGITVIANG-GVICVGIFTFLLVSYGIILNSLKTHSQEGR--RKALSTCSSHIMVVVCFFAPCIFIYARP--VSNFSIDKYIAVFYTVVSPMLNPLIYTLRNSEMKNSIK---------KLWCKTLA---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1L1SQJ6-1", "uniprot_id": "A0A1L1SQJ6_MOUSE", "id": "A0A1L1SQJ6-1", "name": "Olfactory receptor", "aln": "----------------------MGEK----------------SNITEFILLGLTQDPAGRKILFFIFLLIYIVTMVGNLLIVVTVITSPSL-GSPMYFFLASLSLLDALFSTAISPKLIVDLFCDQKT--ISFTACMSQLFIEHLFGGVDIVILVAMAYDRYVAICKPLHYLAIMNRRVCITLLIIAWTGGFTHSLIQIVFVYNLPFCGPNVIDHFICDMSPLLVLACTDTYFIGLTVIANG-GAMCIVIFTLLLGSYGIILRSLKTHSQEGR--RKALSTCSSHILVVILFFVPCIFMYARP--VYNFPIDKCITVFYTIITPMLNPLIYTLRNSEMKTCMK---------KLWCKILSAD-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGM3-1", "uniprot_id": "Q8VGM3_MOUSE", "id": "Q8VGM3-1", "name": "Olfactory receptor", "aln": "----------------------MGQN----------------NNVTEFILLGLTQDPAGQKVLFIMFLLIYIVTIVGNLLIVGTVIASPSL-GSPMYFFLAFLSLMDAVYSTAILPKLLTDLLCDKKT--ISFTACLVQLFVEHLFGGSEVFILVVMAYDRYVAICKPLHYLTIMNRQVCILLLVVSWAGGFAHALLQVISVYLLPFCGPNVIDHFACDMYPLLGLACTDTYFLGLTVVGNN-GAMSIVVFILLLVSYGIILNSLKTHSQEGR--RKALSTCSSHIMVVVLFFVPCIFMYVRP--VSNFPIDKYITVFYTVFTPMLNPLIYTLRNMEIKNCMA---------KLWCKMFTKDIKRDSHH------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R0K2-1", "uniprot_id": "Q9R0K2_MOUSE", "id": "Q9R0K2-1", "name": "Olfactory receptor", "aln": "----------------------MEIP----------------HNITEFFMLGLSQRPEIQRLLFVVFLVIYAVTVCGNMLIVVTVTFSSSL-ASPMYFFLSNLSFIDTCYSSSLAPKLIADSLYEGTT--LSYEGCMAQLFGAHFLGGVEIILLTVMAYDRYVAICKPLHYTTTMTRHLCVVLVAVAWLGGFLHSLVQILLIFQLPFCGPNVINHFVCDLYPLLELACTNTYVIGLLVVANS-GVICLLNFLMLAASYIVILHSLRSHSAEGR--RKALSTCGAHFTVVTMFFVPCIFSYMRP--STTLPIDKNMAVFYGILTPMLNPLIYTLRNEEVKDAMR---------KLFTRSEVVGA------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q60878-1", "uniprot_id": "O4C3D_MOUSE", "id": "Q60878-1", "name": "Olfactory receptor 4C3D", "aln": "----------------------MDSP----------------RNVTEFFMLGLSQNPQVQRMLFGLFLLVFLVSVGGNMLIIITITFSPTL-GSPMYFFLSYLSFIDTCYSSCMTPKLIADSLHEGRA--ISFEGCLAQFFVAHLLGGTEIILLTVMAYDRYVAICKPLHYTTTMTRHVCIVLVAVAWLGGILHSTAQLFLVLQLPFCGPNVINHFVCDLYPLLELACTDTYVIGLLVVANS-GVICLLNFLMLAASYIVILRTLRSHSAEGR--RKALSTCGAHFTVVALFFVPCIFIYMRP--SSTLSIDKIVAVFYCILTPMFNPLIYTLRNAEVKNAMK---------NLWRK------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGN2-1", "uniprot_id": "Q8VGN2_MOUSE", "id": "Q8VGN2-1", "name": "Olfactory receptor", "aln": "-------------------------M----------------SNVTEFILLGLTQDPDLQKLLFIVCLIIYLITLAGNMLISVTIFISPAL-ATPMYFFLSYLSIIDGFYSSSITPKMIYDLISEKST--ISFNGCMTQLFAEHFFAAAEIILLISMAYDRYVAICKPLHYMTIMNRHVCIFLVVAAGIVGFVHGMIQTTFIAQLPFCGPNIINHFICDLIPLLELACTDTHTLGPLIAANS-GSMCLLIFSMLVASYVVILRSLRNHSAEGR--RKALSTCASHVTVVVLFFVPCSYLYVRP--VISFHIDKIVSVFYTLVTPLLNPLIYTLRNEEVKRVMK---------KLLGSNHVKH-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGN4-1", "uniprot_id": "Q8VGN4_MOUSE", "id": "Q8VGN4-1", "name": "Olfactory receptor", "aln": "-------------------------M----------------NNITEFILVGLTQNMELQIFSFVVFFIVYLLTLAGNLLIMVTISSSKAL-GSPMYFFLSFLSLIDGCCSSSMTPKMLADSLSVRKT--ISFSGCMTQVFAEHFFGAAEIILLTVMAYDRYVAICKPLRYTIIMNRFVCGLLVGVAWAGGFIHATIQILFTVWLPFCGPNVIDHFMCDLTPLLKLVCMDTHNLGLFVAANS-GFICLLNFLLLMISYIVILDALKSHSKEGR--CKALSTCVSHITVVILFFVPCIFVYLRP--VITFSIDKAVAVFYTMITPMLNPLIYTLRNTEVKNAMK---------KLCIKVD----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2AV11-1", "uniprot_id": "A2AV11_MOUSE", "id": "A2AV11-1", "name": "Olfactory receptor", "aln": "----------------------MMNK----------------NNVTEFILLGVTRDPELRKILSVLFLIMYMATVFGNLLIVVTITRSPSL-RSPMYFFLLSLSLMDVTYSSVIAPKLIMDSLSERTI--VSFERCMTQLFAEHFFGGVGIILLIVMAYDRYVAICKPLHYVKMMTPRVCCLMVGGAWVGGSMHATIQLLFMYQIPFCSSNIIDHFMCDLFPLLKLACMDTHILGLLVILNS-GVMCVSIFLILIASYMVILCSLKSYSSEGR--RKALSTCSSHFTVVVLFFVPCIFLYMRP--VVTFPIDKAMAVSFTIVEPMLNPLIYTLRNTEVKYAIK---------NMCRKQGSH--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F6XP16-1", "uniprot_id": "F6XP16_MOUSE", "id": "F6XP16-1", "name": "Olfactory receptor", "aln": "-----------------------MHN----------------NSMTEFILLGLTQDPEQQKAIFGVFLILYLMTLIGNFLIMVTIKMSQTL-GSPMYVFLFYLSFADACFSTTTAPRLIVNALSQKKI--ISYNECMTQVFAAHFFGCMEIFVLILMAIDRYVAICKPLRYTTIMNQNICDILVIIAWIGSCIHSSAQIFLALRLPFCGPNVIDHYFCDLQPLMKLACMDTYVINLLVVSNS-GAICMISFIVLFISYIFILYCLRNHSAEGR--RKALSTCTSHFIVVVIFFGPCIFIYTRP--LITLPIDKMVSVFYTIGTPLLNPLIYTLRNSEVKYAMK---------KLWCGKV----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFF8-1", "uniprot_id": "Q8VFF8_MOUSE", "id": "Q8VFF8-1", "name": "Olfactory receptor", "aln": "-----------------------MHN----------------YSVTEFILFGLTQDPEKQKAIFGVFLILYLMTLIGNFLIVMTIKMSQTL-GSPMYFFLFYLSFADACFSTTTAPRLIIDALSQKKI--ITYNECMTQVFAAHFFGCMEIFVLILMAIDRYVAICKPLRYTTIMSQRICGILVILAWVGSCIHSSAQIFLALRLPFCGPNVIDHYFCDLQPLLKLACMDTYVINLLVVSNS-GAICMVSFTLLLISYIFILYSLRNHSVEGR--RKALSTCTSHFIVVVIFFGPCIFIYTRP--PTTFPIDKMVSVFYTIGTPLLNPLIYTLRNAEVKIAMK---------KLWCGKV----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M7H6-1", "uniprot_id": "A0ABK0M7H6_RAT", "id": "A0ABK0M7H6-1", "name": "Olfactory receptor", "aln": "----------------------MMHN----------------NSVTEFILLGLTQDSEKQKAIFGVFLILYLMTLLGNFLIVVTIKMSHTL-SSPMYFFLFYLSFADACFSTTTAPRLIVDLLFQKKV--ITYNECMTQLFAAHFFGCMEIFVLILMAFDRYVAICKPLRYTIIMNQRICGILVILAWLGSCIHSLAQIFLALILPFCGPNVIDHFFCDLQPLMKLACMDTYVINLLVVSNS-GAICTISFIVLLISYIVILYSLRNHSAEGR--RKALSTCTSHFIVVVIFFGPCIFIYTRP--LITLPIDKMLSVFYTIGTPLLNPLIYTLRNAEVKNAMK---------KVWCSKV----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TR16-1", "uniprot_id": "Q7TR16_MOUSE", "id": "Q7TR16-1", "name": "Olfactory receptor", "aln": "-----------------------MYN----------------HTMTEFILFGLTQDPEQQKAIFGVFLILYLMTLMGNFLIMVTIKMSQTL-GSPMYFFLFYLSFADACFSTTTAPRLIADALLQKKI--ITYNECMTQVFAVHFFGCMEIFVLILMAFDRYVAICKPLRYTAIMSQHICGVLVILAWIGSCIHSSAQIFLALRLPFCGPNVIDHYFCDLQPLLKLACMDTYVINLLVVSNS-GAICTVSFIVLLISYIVILYSLRSHSAEGR--RKALSTCTSHIIVVILFFGPCIFIYTWP--PTTFPIDKMVSLFYTIGTPVLNPLIYTLRNAEVKHAMK---------KLWGNKV----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VG21-1", "uniprot_id": "Q8VG21_MOUSE", "id": "Q8VG21-1", "name": "Olfactory receptor", "aln": "----------------------MQLN----------------INVTEFILLGLTQDPSRKNIVFAIFLFFYMGTLLGNFLIIVTIKTSPAL-GSPMYFFLFYLSLSDTCFSTTVAPRTIVDSLLKEAS--ISFNECIIQVFTFHLFGSLEIFILILMAVDRYVAICKPLHYMTIMNRQVCGMLVATVCVGSCIHSSVQIILALSLPFCGPNEIDHYFCDLQPLLKLACSDTYVINLLLVSNS-GTLCTVSFLMLMVSYIIILYSLRNHSAEGR--RKALFTCVSHIIVVILFFVPCIFIYTRP--ATTFPMDKMISVFYTICTPFLNPLIYTLRNAEVKNAMR---------KLWSKKISDDI------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFS5-1", "uniprot_id": "Q8VFS5_MOUSE", "id": "Q8VFS5-1", "name": "Olfactory receptor", "aln": "----------------------MRANQ---------------TWITEVTLLGFQADLAVECFLFGLFSLFYSFTLLGNGIILVVICLDNRL-HTPMYFFLSHLAIVDMSYASNNVPKMLANLVTQRRT--ISFIPCIMQTFLYLAFASIECLILVVMSYDRFVAICHPLHYTVIMSWRVCTIMAAVSWIVGFLLALVHLILILRLPFCGPHKVNHFFCEILSVLKLACADTTLNQVVIFAAC-VFILVGPLCMVLVSYTRILVAILRIQSGEG-RRKAFSTCSSHLCVVGLFFGSAIVMYMAPKSQHPEMQQKILSLFYSLFNPMLNPLIYCLRNAEVKGALR---------RSLLKERSM--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "K9J725-1", "uniprot_id": "K9J725_MOUSE", "id": "K9J725-1", "name": "Olfactory receptor", "aln": "----------------------MKANQ---------------TWITEVTLLGFQADLAVECFLFGLFSLFYSFTLLGNGIIFGIICLDHRL-HTPMYFFLSHLAIVDMSYASNNVPKMLANLVTQRRT--ISFIPCLMQTFLYLAFAHIECLILVVMSYDRFVAICHPLHYTVIMSWRVCTILAAVSWIFSFLLALVHLVLILRLPFCGPHEVNHFFCEILSVLKLACADTTLNQVVIFAAC-VFILVGPLCLVLVSYTRILVAILRIQSGEG-RRKAFSTCSSHLCVVGLFFGSAIVMYMAPKSQHPELQQKILSLFYSLFNPMLNPLIYSLRNAEVKGALR---------RSLLKERSM--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFS6-1", "uniprot_id": "Q8VFS6_MOUSE", "id": "Q8VFS6-1", "name": "Olfactory receptor", "aln": "----------------------MRANQ---------------TWITEVTLLGFQADLSVECFLFGLFSLFYSFTLLGNGIILVVICLDNRL-HIPMYFFLSHLAIVDMSYASNNVPKMLANLVTQRRT--ISFILCIMQTFLYLAFACTECLILVVMSYDRFVAICHPLHYTVIMSWKVCTILAAVSWIAGFLLALVHLVLILKLPFCGPHEINHFFCEILSVLKLACADTTLNQVVILAAC-VFILVGPLCLVLVSYTRILVTILRIQSGEG-RRKAFSTCSSHLCVVGLFFGSAIVMYMAPKSQHPELQQKILSLFYSLFNPMLNPLIYCLRNAEVKGALR---------RSLWKERPM--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VES9-1", "uniprot_id": "Q8VES9_MOUSE", "id": "Q8VES9-1", "name": "Olfactory receptor", "aln": "----------------------MTENQ---------------TWIPEFTLQGFLLSPRMQMLLCGLFSLLYTFTLLGNGVILGLIWLDCRL-HTPMYFFLSHLAIVDISYATNNVPKMLANLLAKKKS--ISFAPCIMQTFLYMAFAHTECLILVMMSYDRYAAICQPLQYSVIMSWKVCTIMAVASWACGSLLALVHVVLILRLPFCGLHEINHFFCEILSVLKLVCADTTLNQIVIFAGS-VFILVGPLCFVLVSYTRILIAILKIQSGEG-RRKAFSTCSSHLCVVGLFFGSAIVMYMAPKSQHPETQQKVLSLFYSLFNPMLNPLIYSLRNAEVKGAVK---------RVLWKQRSR--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFS3-1", "uniprot_id": "Q8VFS3_MOUSE", "id": "Q8VFS3-1", "name": "Olfactory receptor", "aln": "----------------------MKENQ---------------TMVTEFILLGFCLGPRIHVILFALFSVCYIFTLLGNGFTLGLICLEPRL-HSPMYFFLSNLATVDIAYACNTVPQTLVNLLDETKP--ISFAGCMMQTYLFLTFGSTECVLLVVMSYDRYVAICHPLHYTVIMNWRVCTIMAAVSWIFSFLLALVHLVLILRLPFCGPHEVNHFFCEILSVLKLACADTTLNQVVIFAAC-VFALVGPLCLVLVSYTRILVTILRIQSGEG-RRKAFSTCSSHLCVVGLFFGSAIVMYIAPKSQHPEELQKILFLFYSFFNPMLNPLIYSLRNAEVKGALR---------RSLCNENHSQLV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VEV0-1", "uniprot_id": "Q8VEV0_MOUSE", "id": "Q8VEV0-1", "name": "Olfactory receptor", "aln": "------------------------MNQ---------------TWITEVILLGFQVDPSLEMLLFGLFLLFYCLTLMGNGIILGLICLDARL-HTPMYFFLSHLAIVDMSYASSTAPKMLTNMVMHQKS--ISFASCILQTFLYLAFAVTECLILVVMSYDRFVAICHPLKYTLIMSWRVCSILAATCWVFSFLLASLHITLILRLPFCGPQKVNHFFCQIMSVFRLACADTRLNQVVLFAGS-VMVLLGPLCLVLVSYTRILVAILGIHSGEG-RRKAFSTCSSHLCVVGLFFGCAIAMYMAPKSKHSQEQRKILSLFYSLFNPMLNPLIYSLRNTEVKGALR---------RVLWKQRSL--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VEV1-1", "uniprot_id": "Q8VEV1_MOUSE", "id": "Q8VEV1-1", "name": "Olfactory receptor", "aln": "----------------------MGANQ---------------TWVTDFILVGLQLSAGIEMFLFWIFSLLYIFSLLANGIILVVICLDPKL-HTPMYFFLSHLAILDISYASNNVPKMLSNLINQKRT--ISFAPCITQTFLYLAFAASECLILAAMSYDRFVAICHPLHYTVIMSWKVCVALAVTSWSCGFSLSVAHTILLLRLPFCGPQEINHLFCEILAVLKLACADTLINQIVILAAC-VFVLVGPLCSMLVSYTHILWTILKMQSKEG-RRKAFSTCSSHLCVVGLFFGIAMLVYMVPDSDQREEQEKILSLFHSLFNPMLNPLIYSLRNTQVKEAFH---------RALQKKRSV--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P34984-1", "uniprot_id": "OR2A7_MOUSE", "id": "P34984-1", "name": "Olfactory receptor 2A7", "aln": "----------------------MGNNM---------------TLITEFILLGFPLSPRMQMLLFALFSLFYAFTLLGNGTIVGLICLDSRL-HTPMYFFLSHLAIVDIAYACNTVPQMLVNLLDPVKP--ISYAGCMTQTFLFLTFAITECLLLVVMSYDRYVAICHPLRYSAIMSWRVCSTMAVTSWIIGVLLSLIHLVLLLPLPFCVSQKVNHFFCEITAILKLACADTHLNETMVLAGA-VSVLVGPFSSIVVSYACILGAILKIQSEEG-QRKAFSTCSSHLCVVGLFYGTAIVMYVGPRHGSPKEQKKYLLLFHSLFNPMLNPLIYSLRNSDVKNTLK---------RVLRTQRAL--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGP6-1", "uniprot_id": "Q8VGP6_MOUSE", "id": "Q8VGP6-1", "name": "Olfactory receptor", "aln": "----------------------MGGNQ---------------TLITQFILLGFPLSPRMQMLLFALFSLFYAFTLLGNGTILGLICLDSRL-HTPMYFFLSHLAIVDIAYACNTVPQMLVNLMDPAKP--ISFAGCMTQTFLFLTFAHTECLLLVVMSYDRYVAICHPLRYTAIMSWRVCVILVLTSWILGVLLALVHLVLLLPLPFCGSQKVNHFFCEIIAVLKLACSDTRINELMVLAGA-VSVLVGPFSSIVVSYAHILCAILKIKSQQG-RQKAFSTCSSHLCVVGLFYGTAIVMYIGPQHGKSNEQKKYLLLFHSLFNPMLNPLIYSLRNKEVKSALK---------RTLLKEDTS--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VF16-1", "uniprot_id": "Q8VF16_MOUSE", "id": "Q8VF16-1", "name": "Olfactory receptor", "aln": "---------------------MATKNR---------------TEVTEFVLLGLSSQPEMQPVIFGVVLIMYLMAVLGNTLLVLVACSDPKL-HTPMYFLLSQLSLIDISLTTIIVPQMLVHTLSVNRT--ISYNCCMTQLFSFMTVGSMEVHLLGAMAYDRYVAICDPLRYSSIVSHSLCLRITLTSWVVVSLNSLLYSVLVTRLTFCG-NKVTHFFCDITPLLKLSCTRPVVNEMLIFTEG-VAVVVSPIFFIFGSYVRIGIVIAHMHSVAA-LQKALSTCSSHVLVVMFLFGSLVHMYLKPSSSYNLEQDRQVAIFYTLISPMLNPLIYSLRNQEVKGALW---------RLFRKLYLRQCPAWISHNTCQ--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFT2-1", "uniprot_id": "Q8VFT2_MOUSE", "id": "Q8VFT2-1", "name": "", "aln": "----------------------MNNHSS------------SSSSTSDFILLGLSTNPWMQKPLFGIFIIMYLVTVMGNVLIILVIRSDSRL-HTPMYFFLSNLSFMDICFTTVIVPKMLVNFLSETKT--ISYVGCLVQMYFFMALGNTDSYLLASMAIDRLVAICNPLHYDVVMRPQRCLLMLLGSCTISHLHALFRVLLMSRLSFCASHVIKHFFCDTQPVLKLSCSDTSSSQIVVMTET-LAVIVTPFLCILFSYMRIIVTVLRIPSAAG-KWKAFSTCGSHLTVVVLFYGSIIYVYFRPLSMYSVVKDRVATVMYTVVTPMMNPFIYSLRNKDMKRGLR---------KLMGKVHL---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A140T8Q2-1", "uniprot_id": "A0A140T8Q2_MOUSE", "id": "A0A140T8Q2-1", "name": "", "aln": "----------------------MN-----------------SSSTSDFILLGLSTNPWMQKPLFGIFIIMYLVTVMGNVLIILVIRSDSRL-HTPMYFFLSNLSFMDICFTTVIVPKMLVNFLSETKT--ISYVGCLVQMYFFIALANTDSYLLASMAIDRLVAICNPLHYDVVMRSQRCLLMLLGSCTISHLHALFRVLLMSRLSFCASHVIKHFFCDTQPVLKLSCSDTSSSQIVVMTET-LAVIVTPFLCILFSYMKIIVTVLRIPSAAG-KWKAFSTCGSHLTVVALFYGSVIYVYFRPLSMYSVVKDRIATVMYTVVTPMMNPFIYSLRNKDMKRGLR---------KLRDRLHS---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NGR5-1", "uniprot_id": "OR1L4_HUMAN", "id": "Q8NGR5-1", "name": "Olfactory receptor 1L4", "aln": "----------------------METKN-------------YSSSTSGFILLGLSSNPKLQKPLFAIFLIMYLLTAVGNVLIILAIYSDPRL-HTPMYFFLSNLSFMDICFTTVIVPKMLVNFLSETKI--ISYVGCLIQMYFFMAFGNTDSYLLASMAIDRLVAICNPLHYDVVMKPWHCLLMLLGSCSISHLHSLFRVLLMSRLSFCASHIIKHFFCDTQPVLKLSCSDTSSSQMVVMTET-LAVIVTPFLCTIFSYLQIIVTVLRIPSAAG-KWKAFSTCGSHLTVVVLFYGSVIYVYFRPLSMYSVMKGRVATVMYTVVTPMLNPFIYSLRNKDMKRGLK---------KLRHRIYS---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VFP6-1", "uniprot_id": "Q8VFP6_MOUSE", "id": "Q8VFP6-1", "name": "Olfactory receptor", "aln": "----------------------MEGVN-------------QTRFVSEFILLGLSPRPEDQKPLFILFLTIYLVTLTGNLLIILAIRSDPHL-HTPMYFFLSFLSLTDICFTTTIVPKMLVNFLSEKKT--ISYAGCLTQMYFLYALGNSDSCLLAVMAFDRYVAICNPFHYVTIMNHHRCALLVTFSCSFPHFHSLLHTLLLNLLTFCDSNVIHHFLCDLSPLLKLSCSSTFVNEIVIVTEG-ALVLVTPFLCIAFSYIRILVTVLKIPSAAG-KRKAFSTCGSHFTVVTLFYGSIFYVYLQPVSTY-TVKDHIATIVYTVLSSMLNPFIYSLRNKDLKQGLR---------KLISRRHI---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFP4-1", "uniprot_id": "Q8VFP4_MOUSE", "id": "Q8VFP4-1", "name": "Olfactory receptor", "aln": "----------------------MDNSS--------------WTSVSHFVLLGISTNPVEQIPLFLLFLLMYIINISGNFFIVTLIISTSHL-HTPMYIFLSNLALADICFTSTTVPKMLQNIFSSTKV--ISYVGCLAQTYFFICFAAMENFLLAVMAYDRYIAICHPLRYSSILTGMLCAQMVALCHVLSHLHALLHTFLMGRLIFCADNRIPHFFCDLYPLMKISCSSTQLNTLMIHTEG-VIVINGALAFIIASYAFIISAVLRIPSANG-KWRSFSTCGSHLTVVAIFYGTLTWVYFRPLSSYSVVKGRIVTVMYTVVTPMLNPFIYSLRNGDVKEAFR---------KWVRRV-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NG99-1", "uniprot_id": "OR7G2_HUMAN", "id": "Q8NG99-1", "name": "Olfactory receptor 7G2", "aln": "----------------------MEARN-------------QT-AISKFLLLGLIEDPELQPVLFSLFLSMYLVTILGNLLILLAVISDSHL-HTPMYFFLSNLSFLDICLSTTTIPKMLVNIQAQNRS--ITYSGCLTQICFVLFFAGLENCLLAAMAYDRYVAICHPLRYTVIMNPRLCGLLILLSLLTSVVNALLLSLMVLRLSFCTDLEIPLFFCELAQVIQLTCSDTLINNILIYFAA-CIFGGVPLSGIILSYTQITSCVLRMPSASG-KHKAVSTCGSHLSIVLLFYGAGLGVYISSVVTDSPRKTAVASVMYSVFPQMVNPFIYSLRNKDMKGTLR---------KFIGRIPSLLWCAICFGFRFLE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGA0-1", "uniprot_id": "OR7G1_HUMAN", "id": "Q8NGA0-1", "name": "Olfactory receptor 7G1", "aln": "----------------------MGPRN-------------QT-AVSEFLLMKVTEDPELKLIPFSLFLSMYLVTILGNLLILLAVISDSHL-HTPMYFLLFNLSFTDICLTTTTVPKILVNIQAQNQS--ITYTGCLTQICLVLVFAGLESCFLAVMAYDRYVAICHPLRYTVLMNVHFWGLLILLSMFMSTMDALVQSLMVLQLSFCKNVEIPLFFCEVVQVIKLACSDTLINNILIYFAS-SVFGAIPLSGIIFSYSQIVTSVLRMPSARG-KYKAFSTCGCHLSVFSLFYGTAFGVYISSAVAESSRITAVASVMYTVVPQMMNPFIYSLRNKEMKKALR---------KLIGRL-----------FPF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VFF2-1", "uniprot_id": "Q8VFF2_MOUSE", "id": "Q8VFF2-1", "name": "Olfactory receptor", "aln": "-------------------MNNMEKRN-------------QT-TFPGFLLLGLTEDPKLQPVFVSLFFSIYLITILGNLLIILISISDAHL-HTPMYLFLSNLSLNDICLSTSTIPKMLVNIKENSQS--ITYKGCLTQMSFVLIFCGMENCLLAVMAYDRYIAICHPLRYTVIMEPCFCVLLILLSLLISVVDTLMHSLMVLRLSFCTHLEISNFICELPQILKLACSDTLIDNILIYLSA-CIFTGIPISGIVFSYVHIISSILRMSSLEG-KHKAFTTCGSHLSVVSLFYGTAFGVYITSIIMDSSRNTAVASVMYSVVPQMLNPFIYSLRNRDMKEAMG---------KFFSRM-----------ASFL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TRG2-1", "uniprot_id": "Q7TRG2_MOUSE", "id": "Q7TRG2-1", "name": "Olfactory receptor", "aln": "----------------------MESTN-------------QT-DAIEFLLLGLSDDPELQPIIFGLFLFMYLVTFLGNLIITLTISAECHL-HTPMYFFLSNLSVADICISSTTVPKMLLNIQTPDHR--ITYSGCLTQACFVLLFAGLENCLLAAMAYDRYVAICHPLRYTVIMNSCFCSILIVVSLAISAVNALLLSLMVLHLNFCTEVEIPHFFCELAQIIKLACSDTLINNILIYISA-FMFGGIPFFGIFLSYTEIVSSVLKIPSRQG-RHKAFSTCGSHLSVVSLFYGTGLGVYISSAVTESPRKTAVASVMYSIVTQMLNPFIYSLRNRDMKEALR---------KHVGRI-----------ASIV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1D5RMH6-1", "uniprot_id": "A0A1D5RMH6_MOUSE", "id": "A0A1D5RMH6-1", "name": "Olfactory receptor", "aln": "----------------------MELKN-------------QT-AVSEFHLLGLTDNHRMLPLVFIMFLFMYLITVFGNLIIIMAISSGSQL-HTPMYLFLSILSINDICYSTVTIPKMLVNIQAHDDS--ISYIECLSQICFVSIFGGMENFLLAVMAYDRYVAICKPLRYTVIMNPICCVLMVLFSLFFSIMDALLHSLMVLRLSFCTDLEIPHFFCELAQIIKLACSDTFLNNFLIFVAA-FVFGGGPVCGIIFSYIYIVSSVLRMPSSGG-KHRAFSTCASHLSVVSLFYGTGFGVYISSAVTDSLRNTAMASMMYSVVPPLLNPFIYSLRNREMKEALR---------KLVGRL-----------IYLI--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGG6-1", "uniprot_id": "Q8VGG6_MOUSE", "id": "Q8VGG6-1", "name": "Olfactory receptor", "aln": "----------------------MELEN-------------QT-RVIEFFLLGLSEDPELQPILFGLFLLMYLVTVSGNLLIILAIVSDAHL-HTPMYFFLSNLSFTDICFSTTTVPKMLTNLQKQSKS--ISYTGCITQLSFVLLFAGMENFLLAAMAYDRYVAICNPLRYTDIMKLHLCFVMIFLSLYISIVDALLHGLMTLRLSFCTFLEIPHFFCELYQVIKIACSDTLINNILIYVMS-SALGGMPLVGIIFSYYKIISSILRMPSPGG-RHKAFSTCGSHLSVVSLFYGTAFGVYISSAFTESYRRTSVASLMYTVFPPMLNPFIYSLRNKDMKKALR---------KIV--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2I3BPT4-1", "uniprot_id": "A0A2I3BPT4_MOUSE", "id": "A0A2I3BPT4-1", "name": "Olfactory receptor", "aln": "----------------MTLARNTEYKN-------------QT-FASEFILLGLTDDPELQLILFGIFLFMYLVTVLGNLIIICAVSLHPKL-HTPMYFFLSNLSFTDICFITSTVPKMLVNIQKQNNA--ISYPDCLTQMYFVIFLGGMENFLLAAMAYDRYVAICHPLRYTVIMNPSICILLTLLSVLSSTIDALLHSLLVLRLSFCTYLKIPHFFCELAHIIKLSCSDTLINNIVVYLAT-FIFGGLPFWGIILSYVQIVYSVLKKPSVRG-SYKALSTCGSHLSVVSLFYGSVIGVYISFAVTDSSRKAAVASVLYTVVPQMLNPFVYSLRNKDMKEAVR---------KLCGGIL----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TRG4-1", "uniprot_id": "Q7TRG4_MOUSE", "id": "Q7TRG4-1", "name": "Olfactory receptor", "aln": "----------------------MEISN-------------QS-GISEFFLTGLTYSPAIESFIFSLFLSIYFVTIFGNILIILAVRLDYHL-HTPMYFFIANLSFTDICISTTIIPKMLLNIETQNQS--ITYTGCLSQVCFVLIFGGLESCLLAVMAYDRYLAIVHPLRYTVIMNPCLCVLLVLLSLFISTINALLHSLMLLKLSFCKDQNILHFFCELVQVIKHACSDTFINTLLIYTVT-SVFAGFPLAGIIFSYIQIVSSILKISSVQG-RNKAFSTCGSHLSVVSLFYGTAFGVYMSSAVSDSSVKNIVFSMMYTVVPQMLNPFIYSLRNREMKQAMR---------HLLFPVVLSSP------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFF4-1", "uniprot_id": "Q8VFF4_MOUSE", "id": "Q8VFF4-1", "name": "Olfactory receptor", "aln": "----------------------MEPGN-------------QT-GTSYFILMRLNYDPTVEPLIFGFFMFTYLVTIVGNLLIIIAVSSDSHL-QTPMYLFLSKLSFTDICLSTTTVPNMLKNIHTQDHS--ISYTGCLTQACFVLSFAVLESSVLAAMAYDRYAAICHPLNYTVIMNPQFCGLLILLSLIISTANSLLQCLMILRLSFCTNNELPLFFCELAQVIKLACSDTLINYILIYLAT-FIFGGIPISGIIFSYTRIVSSILKISSLRG-RYKAFSTCGSHFVVVSLFYGAAVGVYICSAITVSPQITTVSYMMYTVLPQMLNPFIYSLRNRDMKKALG---------KLITKVSCFL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NG95-1", "uniprot_id": "OR7G3_HUMAN", "id": "Q8NG95-1", "name": "Olfactory receptor 7G3", "aln": "----------------------MKAGN-------------FS-DTPEFFLLGLSGDPELQPILFMLFLSMYLATMLGNLLIILAVNSDSHL-HTPMYFLLSILSLVDICFTSTTMPKMLVNIQAQAQS--INYTGCLTQICFVLVFVGLENGILVMMAYDRFVAICHPLRYNVIMNPKLCGLLLLLSFIVSVLDALLHTLMVLQLTFCIDLEIPHFFCELAHILKLACSDVLINNILVYLVT-SLLGVVPLSGIIFSYTRIVSSVMKIPSAGG-KYKAFSICGSHLIVVSLFYGTGFGVYLSSGATHSSRKGAIASVMYTVVTPMLNPLIYSLRNKDMLKALR---------KLISRIPSFH-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VGG4-1", "uniprot_id": "Q8VGG4_MOUSE", "id": "Q8VGG4-1", "name": "Olfactory receptor", "aln": "----------------------MKPEN-------------QT-NILEFLLLGFSQYPEHQPMLFGLFLLMFVVAVLGNLLIILAVSIDSHL-HTPMYFFLSNLSFSDIGFISTTVPKMLVNIQTQSKS--ISYAECITQIYFFMLFGGMDTLLLTVMAYDRFVAICHPLHYSVIMNPQLSGLLVLVSWFISFSYSLIQSLLMLRLSFCTNQIIKHFYCEYAKALTIACSDTLINHILLYIVI-WVLGFIPFSGILYSYYKIFSSILRIPSTDG-KYKAFSTCGSHLSVVSLFYGTGLSVYLSSDATSSSGKGVVASVMYTVVTPMLNPFIYSLRNKDIKKAL----------KTLGRILLLK-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TRF0-1", "uniprot_id": "Q7TRF0_MOUSE", "id": "Q7TRF0-1", "name": "Olfactory receptor", "aln": "----------------------MKPEN-------------QT-NILEFLLLGFSQYPEHQPMLFGLFLLMFVVAVFGNLLIILAVSIDSHL-HTPMYFFLSNLSFSDIGFISTTIPKMLVNIQTQSKS--ISYAECITQIYFFMLFGGMDILLLTVMAYDRFVAICHPLHYSVIMNPQLSGLLVLVSWFISFSYSLIQSLLMLRLSFCTNQIIKHFYCEYSRALTIACSDTLINHILLYILI-CVLGFIPFSGILYSYCKIVSSILRIPSTDG-KYKAFSTCGSHLSVVSLFYGTGLGVYLSSDVTSSSGKDVVASVMYTVVTPMLNPFIYSLRNKDIKKAL----------KTLGRILLLK-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76099-1", "uniprot_id": "OR7C1_HUMAN", "id": "O76099-1", "name": "Olfactory receptor 7C1", "aln": "----------------------METGN-------------QT-HAQEFLLLGFSATSEIQFILFGLFLSMYLVTFTGNLLIILAICSDSHL-HTPMYFFLSNLSFADLCFTSTTVPKMLLNILTQNKF--ITYAGCLSQIFFFTSFGCLDNLLLTVMAYDRFVAVCHPLHYTVIMNPQLCGLLVLGSWCISVMGSLLETLTVLRLSFCTEMEIPHFFCDLLEVLKLACSDTFINNVVIYFAT-GVLGVISFTGIFFSYYKIVFSILRISSAGR-KHKAFSTCGSHLSVVTLFYGTGFGVYLSSAATPSSRTSLVASVMYTMVTPMLNPFIYSLRNTDMKRALG---------RLLSRATFFNGDITAGLS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O60412-1", "uniprot_id": "OR7C2_HUMAN", "id": "O60412-1", "name": "Olfactory receptor 7C2", "aln": "----------------------MERGN-------------QT-EVGNFLLLGFAEDSDMQLLLHGLFLSMYLVTIIGNLLIILTISSDSHL-HTPMYFFLSNLSFADICFTSTTVPKMLVNIQTQSKM--ITFAGCLTQIFFFIAFGCLDNLLLTMTAYDRFVAICYPLHYTVIMNPRLCGLLVLGSWCISVMGSLLETLTILRLSFCTNMEIPHFFCDPSEVLKLACSDTFINNIVMYFVT-IVLGVFPLCGILFSYSQIFSSVLRVSARG--QHKAFSTCGSHLSVVSLFYGTGLGVYLSSAVTPPSRTSLAASVMYTMVTPMLNPFIYSLRNKDMKGSLG---------RLLLRATSLKEGTIAKLS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TQU8-1", "uniprot_id": "Q7TQU8_MOUSE", "id": "Q7TQU8-1", "name": "Olfactory receptor", "aln": "----------------------MEREN-------------QT-GERNFLLLGFTEDSDLQSFFFGLLLSMYLVTITGNLLIIVAIISDPHL-HMPMYLFLSNLSIADIGFTSTTIPKVLQNIRTQSKF--ISFSGCITQIFFFIVFGCLDNLLLSVMAYDRFVAICHPLHYVVIMNSCFCAMLALGSWIVSVMSSLPETLTVLRLSFCTNMEIPHFFCDLPEVLKLACSDTLVNNIVTYSIT-IVIAGFPFSGILLSYSKIFSSILRIPSAGG-KYKAFSTCGSHLLVVFLFYSNGLGVYLSSAATSSSRMSLVASLMYSIVTPMLNPFIYSLRNKDMQKALG---------KLLRKIMLLGEGTMVGLP-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NG98-1", "uniprot_id": "OR7D4_HUMAN", "id": "Q8NG98-1", "name": "Olfactory receptor 7D4", "aln": "----------------------MEAEN-------------LT-ELSKFLLLGLSDDPELQPVLFGLFLSMYLVTVLGNLLIILAVSSDSHL-HTPMYFFLSNLSFVDICFISTTVPKMLVSIQARSKD--ISYMGCLTQVYFLMMFAGMDTFLLAVMAYDRFVAICHPLHYTVIMNPCLCGLLVLASWFIIFWFSLVHILLMKRLTFSTGTEIPHFFCEPAQVLKVACSNTLLNNIVLYVAT-ALLGVFPVAGILFSYSQIVSSLMGMSSTKG-KYKAFSTCGSHLCVVSLFYGTGLGVYLSSAVTHSSQSSSTASVMYAMVTPMLNPFIYSLRNKDVKGALE---------RLLSRADSCP-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96RA2-1", "uniprot_id": "OR7D2_HUMAN", "id": "Q96RA2-1", "name": "Olfactory receptor 7D2", "aln": "----------------------MEAGN-------------QT-GFLEFILLGLSEDPELQPFIFGLFLSMYLVTVLGNLLIILAISSDSHL-HTPMYFFLSNLSWVDICFSTCIVPKMLVNIQTENKA--ISYMDCLTQVYFSMFFPILDTLLLTVMAYDRFVAVCHPLHYMIIMNPHLCGLLVFVTWLIGVMTSLLHISLMMHLIFCKDFEIPHFFCELTYILQLACSDTFLNSTLIYFMT-GVLGVFPLLGIIFSYSRIASSIRKMSSSGG-KQKALSTCGSHLSVVSLFYGTGIGVHFTSAVTHSSQKISVASVMYTVVTPMLNPFIYSLRNKDVKGALG---------SLLSRAASCL-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60892-1", "uniprot_id": "O7A42_MOUSE", "id": "Q60892-1", "name": "Olfactory receptor 7A42", "aln": "----------------------MESGN-------------STRRIPSFFLLGFSENPHLQFLIFVLFLSMYLVTVLGNLLIIMVIITQSPL-HTPMYFFLANLSFVDICFTSTTVPKMLVNIQTQSKA--ITYADCISQMSVFLVFAELDNFLLAVMAYDRYVAICHPLYYTFIVNQHLCILMVLLSWVVSILHAFLQSSIVLQLTFCGDVKIPHFFCELNQLSQLTCLDSLSSHLIMNLVP-VLLAVISFSSILYSYFKIVSSICSISSVQG-KYTAFSTCVSHLSIVFLFYSTGLGVYVSSAVVQSSHSAARASVMYTVVTPMLNPFIYSLRNKDVKKAL----------ERLLEGKL---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9Q5G9-1", "uniprot_id": "E9Q5G9_MOUSE", "id": "E9Q5G9-1", "name": "Olfactory receptor", "aln": "----------------------MESGN-------------STRRIPSFFLLGFSENPHLQFLIFVLFLSMYLVTVLGNLLIIMVIITQSHL-HTPMYFFLANLSFVDICFTSTTVPKMLVNIQTQSKA--ITYADCISQMSVFLVFAELDNFLLAVMAYDRYVAICHPLYYTVIVNQQLCILMVLLSWVVSILHAFLQSSIVLQLTFCGDVKIPHFFCELNQLSQLTCSDSFSSQLIMNLVP-VLLAVISFSSILYSYFKIVSSICSISSVQG-KYKAFSTCVSHLSIVSLFYSTGLGVYVSSVVIQSSHSAARASVMYTVVTPMLNPFIYSLRNKDVKKAV----------ERLLEGKL---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TQU9-1", "uniprot_id": "Q7TQU9_MOUSE", "id": "Q7TQU9-1", "name": "Olfactory receptor", "aln": "----------------------MESGN-------------RTRRISSFFLLGFSENPHLQFLIFVLFLSMYLVTVLGNLLIIMVTITQSPL-HTPMYFFLANLSFVDICFTSTTVPKMLVNIQTQSKA--ITYADCISQMSVFLVFGELDNFLLAVMAYDRYVAICHPLYYTVIVNQQLCMLMVLLSWVVSILHAFLQSSIVLQLTFCGDVKIPHFFCELNQLSQLTCSDSLSSHLIMHLVP-VLLGAISFSSILYSYFKIVSSICSISSVQG-KYKAFSTCVSHLSIVSLFYSTGLGVYVSSAVVQSSHSSARASVMYTVVTPMLNPFIYSLRNKDVKKAV----------ERLLEGKL---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76100-1", "uniprot_id": "OR7AA_HUMAN", "id": "O76100-1", "name": "Olfactory receptor 7A10", "aln": "----------------------MKSWN-------------NT-IILEFLLLGISEEPELQAFLFGLFLSMYLVTVLGNLLIILATISDSHL-HTPMYFFLSNLSFVDICFVSTTVPKMLVNIQTHNKV--ITYAGCITQMCFFLLFVGLDNFLLTVMAYDRFVAICHPLHYMVIMNPQLCGLLVLASWIMSVLNSMLQSLMVLPLPFCTHMEIPHFFCEINQVVHLACSDTFLNDIVMYFAV-ALLGGGPLTGILYSYSKIVSSIRAISSAQG-KYKAFSTCASHLSVVSLFYGTCLGVYLSSAATHNSHTGAAASVMYTVVTPMLNPFIYSLRNKHIKGAM----------KTFFRGKQ---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O14581-1", "uniprot_id": "OR7AH_HUMAN", "id": "O14581-1", "name": "Olfactory receptor 7A17", "aln": "----------------------MEPEN-------------DT-GISEFVLLGLSEEPELQPFLFGLFLSMYLVTVLGNLLIILATISDSHL-HTPMYFFLSNLSFADICFISTTIPKMLINIQTQSRV--ITYAGCITQMCFFVLFGGLDSLLLAVMAYDRFVAICHPLHYTVIMNPRLCGLLVLASWMIAALNSLSQSLMVLWLSFCTDLEIPHFFCELNQVIHLACSDTFLNDMGMYFAA-GLLAGGPLVGILCSYSKIVSSIRAISSAQG-KYKAFSTCASHLSVVSLFCCTGLGVYLTSAATHNSHTSATASVMYTVATPMLNPFIYSLRNKDIKRAL----------KMSFRGKQ---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NGA2-1", "uniprot_id": "OR7A2_HUMAN", "id": "Q8NGA2-1", "name": "Putative olfactory receptor 7A2", "aln": "---------------------MVKAGN-------------ET-QISEFLLLGFSEKQELQPFLFGLFLSMYLVTVLGNLLIILAAISDSCL-HTPMYFFLSNLSFVDICFASTMVPKMLVNIQTQSKV--ITYAGCITQMCFFVLFIVLDSLLLTVMAYDQFVAICHPLHYTVIMSPQLCGLLVLVSWIMSVLNSMLQSLVTLQLSFCTDLEIPHFFCELNEMIHLACSDTFVNNMVMHFAA-VLLDGGPLVGILYSYCRIVSSIRAISSTQG-KYKALSTCASHLSVVSIFYGTGLGVYLSSTMTQNLHSTAVASVMYTVVTPMLNPFIYSLRNKDIKGAL----------TQFFRGKQ---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q15622-1", "uniprot_id": "OR7A5_HUMAN", "id": "Q15622-1", "name": "Olfactory receptor 7A5", "aln": "----------------------MEPGN-------------DT-QISEFLLLGFSQEPGLQPFLFGLFLSMYLVTVLGNLLIILATISDSHL-HTPMYFFLSNLSFADICVTSTTIPKMLMNIQTQNKV--ITYIACLMQMYFFILFAGFENFLLSVMAYDRFVAICHPLHYMVIMNPHLCGLLVLASWTMSALYSLLQILMVVRLSFCTALEIPHFFCELNQVIQLACSDSFLNHMVIYFTV-ALLGGGPLTGILYSYSKIISSIHAISSAQG-KYKAFSTCASHLSVVSLFYGAILGVYLSSAATRNSHSSATASVMYTVVTPMLNPFIYSLRNKDIKRALGIHLLWGTMKGQFFKKCP---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JHB2-1", "uniprot_id": "O7A40_MOUSE", "id": "Q9JHB2-1", "name": "Olfactory receptor 7A40", "aln": "----------------------MELKN-------------DT-QISKFILLGISEDPLWQPFLFGLFLFMYLVTLLGNLLIIIATITDSHL-HTPMYFFLSNLSFADICFTSASIPKMLVNIQTKNKV--ITYEGCISQVFFFILFGVLDNFLLAVMAYDRYVAICHPLHYMVIMNCRLCGFLVLGSWVTTALNSLLQSSMALRLSFCTDLKIPHFVCELNQLVLLACNDTFPNDMVMYFAA-ILLGGGPLAGILYSYSKIVSSIRAISSSQG-KYKAFSTCASHLSVVSLFYSTLLGVYLSSSFTQNSHSTARASVMYSVVTPMLNPFIYSLRNKDLMGAL----------RRLLRRKS---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TRF6-1", "uniprot_id": "Q7TRF6_MOUSE", "id": "Q7TRF6-1", "name": "Olfactory receptor", "aln": "----------------------MEPYN-------------LT-GTLEFILLGLSEDPELQLILFALFLLIYLLTMLGNVLIILAISCDSHL-HSPMYFFLYNLSLSDMGFSSTTIPKMLINLHAHKRS--TTYAECLTQVSFFILFGCMDSFLLAVMAYDRWVAICHPLHYQVILNPCRCRYLVVMSFCISLIDSQVHCFMVSQLTFCTNIEIPHFFCDVPELVKLACSNTTINDIAMFLSS-IIVGFLPASGIFYSYYKITSSIFRVPSLLG-KYKAFSTCGSHLSVVCLFYGTGIGVYLSSTVSGSSRESMVASVMYTMVVPMMNPFIYSLRNRDIKKALW---------KIVCKIT----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TRF5-1", "uniprot_id": "Q7TRF5_MOUSE", "id": "Q7TRF5-1", "name": "Olfactory receptor", "aln": "----------------------MEPYN-------------ST-GTLEFILLGLSEDPELQFILFALFLLIYLLTVLGNVLIILAISCDSHL-HSPMYFFLYNLSLADMGFSSTTIPKMLINLHAHNRS--ITYAECLTQVSFFILFGCMDSILLAVMAYDRWVAICHPLHYQVILNPCRCRYLVVMSFCISLIDSQVHCFMVSQLTFCTNIKIPHFFCDVPELVKLACSNTTINDIVMFLLS-IITGFLPASGIFYSYYKITSSIFRVPSLLG-KYKAFSTCGSHLSVVCLFYGTGIGVYLSSTVSSSSKESMVASVMYTMVVPMMNPFIYSLRNRDIKKALW---------KIVCKIT----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1L1SUS1-1", "uniprot_id": "A0A1L1SUS1_MOUSE", "id": "A0A1L1SUS1-1", "name": "Olfactory receptor", "aln": "----------------------MEIIY-------------SL-RTLEFILLGLSEDPELQLILFALFLLIYMLTVLGNVLIILAISSDSHL-HSPMYFFLYNLSLSDMGFSSTTIPKMLINLHAHNRS--ITYAECLTQVSFFFLFGGMDSLLLAVMAYDRWVAICHPLYYQVILSPCLCRCLVIVSLFISLVSSQVHCLLVSQLTFCINVEIPHFFCDVPELVKLACSNTTISDIVIFLLG-IILGFLPASGIFYSYYKITSSIFRVPSLLG-KYKAFSTCGSHLSVVCLFYGTGIGVYLSSTVSSSSRESMVASVMYTMVVPMMNPFIYSLRNRDIKKALW---------KIVRQIT----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFF7-1", "uniprot_id": "Q8VFF7_MOUSE", "id": "Q8VFF7-1", "name": "Olfactory receptor", "aln": "----------------------MELYN-------------LT-SNLEFLLLGLSEDPELQPVLFALFLLIYLLTVLGNVLIILAISCDSHL-HSPMYFFLYNLSLSDMGFSSTTIPKMLINLHAHNRT--ITYAECLTQVSFFFLFGCMDSVLLAVMAYDRWVAICHPLHYQVILNPRLCRYLVVMSFCISLIDSQVHCFMVSQLKFCTNIKIPHFFCDVPELLKLACSDTSINSIVIFLVS-IIVGFLPASGIFYSYYKIISSIVRVPSSGG-KCKAFSTCGSHLSVVCLFYGTGLGVYLSSSISSSSKESVVTSVMYTMVVPMINPFIYSLRNKDIKKALQ---------KIFSQIIMLPTYIIP--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFJ1-1", "uniprot_id": "Q8VFJ1_MOUSE", "id": "Q8VFJ1-1", "name": "Olfactory receptor", "aln": "----------------------MEPYN-------------LT-GALEFLLLGLSEDPELQPVLFALFLLIYLLTVLGNVLIILAISSDSHL-HSPMYFFLYNLSLSDMGFSSTTIPKMLINMQTHNKS--ITYAACLTQVSFFTLFGCMDSLLLTVMAYDRWVAICRPLYYQVILNPGLCRRLVLMLFFISYMNSLVHYFIVSQLKFCTNMEIPHFFCDIPELLKLACSDTSINNLFRFLLS-IIFGFLPVSGIFYSYYKIISSIIRVPSLLG-KYKAFSTCGSHLSVVCLFYGTGLEAYLSSTISRSTRENMLASVIYTMRVPMINPFIYSLRNRAMKKALQ---------KIFS-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFI7-1", "uniprot_id": "Q8VFI7_MOUSE", "id": "Q8VFI7-1", "name": "", "aln": "--------------MIN-----NDVEN-------------LK-DVLEFHLMALSEDPELQLLLFGLFLSVYLVTVLGNLLIILIIIFDSNL-HNPMYFFLSNLSLIDILFISTTIPKMIVGIKMHSRV--ISYAGCLTQMSLFLFFVCMDDMILNVMAYDRFVAICHPLHYTVLMNPQVCVILILLSFSVSVFDSQLHNLIALQDTCFRDVEIANFFCHPSQLLNLACTNTLSSNIVIYFIG-VILGIFPVLGIILSYCKIVFSILKIPSSSG-KYKAFSTCGSHLLVVCLFYGTGIGVYLGSAVSHSPRKNAVASLMYTAVSPMLNPFIYTLRNRDISNALK---------RFHSRFS----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFI8-1", "uniprot_id": "Q8VFI8_MOUSE", "id": "Q8VFI8-1", "name": "Olfactory receptor", "aln": "--------------MMK-----LKMEN-------------IT-YVSQFYLLRVSDDPELQPFLSGLFLSMYLISVLGNLIIILIVSSFSHL-HTPMYFFLSILSLADIGFISTTVPNMIAELQIHSPV--ISYVGCLTQMSLFIIFACMDSMLLAVMAYDRFVAICHPLRYAIIMNPCRCGILVLMSFSASLFESLLHNLVALQLKCFKDVAIANFFCHPSQLLNLSCNNTFNNNILMYVIG-VILGVFPLSGILISYFKIISSILRITSSSG-RYKAFSTCGSHLAVVCLFYGTGLGEYFGSLLSHSSGNNVVASLMYTVVTPMLNPFIYSLRNQDISDSLK---------RLHF-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IFN5-1", "uniprot_id": "O7E24_HUMAN", "id": "Q6IFN5-1", "name": "Olfactory receptor 7E24", "aln": "----MSYFPILFFFFLKRCPSYTEPQN-------------LT-GVSEFLLLGLSEDPELQPVLAGLFLSMYLVTVLGNLLIILAVSSDSHL-HTPMYFFLSNLSLADIGFTSTTVPKMIVDMQTHSRV--ISYEGCLTQMSFFVLFACMDDMLLSVMAYDRFVAICHPLHYRIIMNPRLCGFLILLSFFISLLDSQLHNLIMLQLTCFKDVDISNFFCDPSQLLHLRCSDTFINEMVIYFMG-AIFGCLPISGILFSYYKIVSPILRVPTSDG-KYKAFSTCGSHLAVVCLFYGTGLVGYLSSAVLPSPRKSMVASVMYTVVTPMLNPFIYSLRNKDIQSALC---------RLHGRIIKSHHLHPFCYMG----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0VAX9-1", "uniprot_id": "O7178_MOUSE", "id": "Q0VAX9-1", "name": "Olfactory receptor 7E178", "aln": "MMDRYSFIMHQHRDDTVWCPSKIEEQN-------------IT-RISEFHLMGLSDDLQLQPILFGLFLSMYLVTLLGNLLIILTVSSDSHL-HSPMYFFLSNLSLADVSFTSTTLPKMIVDIQTHNRA--ISYSGCLTQMSFFMLFGCLDSLLLTAMAYDRFVAICHPLHYQFIMNPRLCGLLVFLSVLISLFVSQLHNSVVLQLTYFKSVDISHFFCDPSQLLNLACSDTFTNNIVMYFVG-AISGFLPISGIFFSYYKIVSSILRMPSPGG-KYKAFSTCGSHLSVVCLFYGTGLGVYLSSAVSLSPRKGAVASIVYTVVTPMLNPFIYSLRNQDIKRAMW---------RLLRKTV----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PX82-1", "uniprot_id": "E9PX82_MOUSE", "id": "E9PX82-1", "name": "Olfactory receptor", "aln": "--------MSLQRHSLGHCSNNIELQN-------------LT-LVSEFHLMRISDDPELQPILFGLFLSMYLVTVLGNLIIILAVNSDSNL-HTPMYFFLCNLSLADICFISTTVPKMIVNIQTHSKE--IIYVGCLTQMSFLILFGCMDGLLLTVMAYDRFVAVCHPLHYSLIMNPRLCGSLVCLSLLISLVDSQAHNLIALQIIYFKDVKISNFFCDPAQLLNLACFNTFINNIVMYFVG-AISGLLPISGIFFSYYKIVFSILKIPSKGG-RYKAFSTCGSHLSVVCLFYGTAIGVYLGSAVSHSPRSTAVASLIYTVVTPMLNPFIYSLRNKDIKRAVK---------RLHRRML----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P34982-1", "uniprot_id": "OR1D2_HUMAN", "id": "P34982-1", "name": "Olfactory receptor 1D2", "aln": "----------------------MDGGN-------------QS-EGSEFLLLGMSESPEQQRILFWMFLSMYLVTVVGNVLIILAISSDSRL-HTPVYFFLANLSFTDLFFVTNTIPKMLVNLQSHNKA--ISYAGCLTQLYFLVSLVALDNLILAVMAYDRYVAICCPLHYTTAMSPKLCILLLSLCWVLSVLYGLIHTLLMTRVTFCGSRKIHYIFCEMYVLLRMACSNIQINHTVLIATG-CFIFLIPFGFVIISYVLIIRAILRIPSVSK-KYKAFSTCASHLGAVSLFYGTLCMVYLKPLHTYSV-KDSVATVMYAVVTPMMNPFIYSLRNKDMHGALG---------RLLDKHFKRLT------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VFP5-1", "uniprot_id": "Q8VFP5_MOUSE", "id": "Q8VFP5-1", "name": "", "aln": "----------------------MMTRN-------------HS-SVSEFLLLGLSEHWEQEPLLFGIFLVIYLVTVVGNTLIILAIVSDPHL-HSPMYFFLANLSLTDMCLSSTTVPRMLVNIQTQRHS--IPYAGCLSQIYFFLWFIGLDVFLLAVMAYDRLVAICYPLHYTLVMSPRCCILLVTTSLFLAHSYALTHIILLSQLSFCMDNIILHFFCELLPMLKLSCSNTYANQCVLLYWGGALTVLIPL-LIIVSYVRIVATIVRVPSASG-KWKTFSTCGSHLSAVCLFYVSAIGVYFIPYAADSASRDRIASVMYAVVTPMLNPFIYSLRNKDMTSALR---------RFLNKILLQPPQS----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47890-1", "uniprot_id": "OR1G1_HUMAN", "id": "P47890-1", "name": "Olfactory receptor 1G1", "aln": "----------------------MEGKN-------------LT-SISECFLLGFSEQLEEQKPLFGSFLFMYLVTVAGNLLIILVIITDTQL-HTPMYFFLANLSLADACFVSTTVPKMLANIQIQSQA--ISYSGCLLQLYFFMLFVMLEAFLLAVMAYDCYVAICHPLHYILIMSPGLCIFLVSASWIMNALHSLLHTLLMNSLSFCANHEIPHFFCDINPLLSLSCTDPFTNELVIFITG-GLTGLICVLCLIISYTNVFSTILKIPSAQG-KRKAFSTCSSHLSVVSLFFGTSFCVDFSSPSTHSAQKDTVASVMYTVVTPMLNPFIYSLRNQEIKSSLR---------KLIWVRKIHSP------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TRX7-1", "uniprot_id": "Q7TRX7_MOUSE", "id": "Q7TRX7-1", "name": "Olfactory receptor", "aln": "----------------------MTGN--------------NQTLISKFLLLGLPILSEYHFLFYALFLAMYLTTILGNLLIIALVRLDSHL-HTPMYLFLSNLSFSDLCFSSVTIPKLLQNMQSQVPS--ISYVGCLTQLYFFMVFGDMESFLLVVMAYDRYVAICFPLHYTSIMSTKFCTSLVLLLWMLTTSNALMHTLLMARLSFCEKNVILRFFCDISALLKLSCSDTFVNELMIFIMG-GIIIIIPFLLIVMSYVRIFFSILKVPSTQG-IHKVFSTCGSHLSVVSLFYGTIIGLYLCPSSNNSTVKESAMAMMYTVVTPMLNPFIYSLRNRDMKRALI---------RVICSKKISL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGR3-1", "uniprot_id": "Q8VGR3_MOUSE", "id": "Q8VGR3-1", "name": "Olfactory receptor", "aln": "----------------------MAGK--------------NQTLILEFLLLGLPISSEYHLLFYALLLAMYLTTLLGNLLIILLVRLDSHL-HTPMYLFLSNLSFSDLCFSSVTIPKLLQNMQSQVPT--ISYADCLTQLYFFMVFGDMESFLLVVMAYDRYVAICFPLHYTSIMSTKFCALLVLLLWMLTISHALLHTLLMARLSFCEKNVILHFFCDISALLKLSCSDTYVNELMIFIMG-GIISIIPFLLIVMSYVRIFFSILKVPSSQD-IHKVFSTCGSHLSVVTLFYGTIIGLYLCPSGNNSTVNEISMAMMYTVVTPMLNPFIYRLRNRDMKRALI---------RVIFSKKISL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TRX6-1", "uniprot_id": "Q7TRX6_MOUSE", "id": "Q7TRX6-1", "name": "Olfactory receptor", "aln": "----------------------MTGN--------------NQTFILEFLLLGLPIPSEYQLLFNALFLAMYLTTLLGNLLIILLVRLDSHL-HMPMYLFLSNLSFSDLCFSSVTIPKLLQNMHSQVPT--ISYAGCLTQLYFFMVFGDMESFLLVAMAYDRYVAICFPLHYTSIMSTKLCVSLVLLLWMLTIFHALLHTLLTARLSFCEKNVILHFFCDLPALLKLSCSDTFVNELMIFILG-GIIIIIPFLLIGMSYVRIFFSILKVPSTQG-IHKVFSTCGSHLSVVSLFYGTIIGLYLCPSSNNSTLKKTAMALMYTLVTPMLNPFIYSLRNRDIKRALI---------RVISSKKISL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGR5-1", "uniprot_id": "Q8VGR5_MOUSE", "id": "Q8VGR5-1", "name": "Olfactory receptor", "aln": "------------------------MN--------------NKTVITQFLLLGLPIPPEYQHLFYALFLAMYLTTILGNLLIIVLIQLDSHL-HTPMYLFLSNLSFSDLCFSSVTMPKLLQNMQSQDPS--IPYGGCLAQIFFFMLFGDMESFLLVAMAYDRYVAICFPLHYTSIMSPKVCTFLVLLLWILTTSHATMQILLTVRLSFCENNVLLNFFCDIFVLLKLACSDTYVNDLMILIMG-GLIIVIPFLLIVISYARIISSTLKVPSTQG-IHKVFSTCGSHLSVVSLFYGTIIGLYLCPSGNNFSLKGSAMAMMYTVVTPMLNPFIYSLRNRDMKRALI---------RIIGSKKISL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGR6-1", "uniprot_id": "Q8VGR6_MOUSE", "id": "Q8VGR6-1", "name": "Olfactory receptor", "aln": "----------------------MKMN--------------NKTVITQFLLLGLPISLEYKHLFYALFLAMYLTTVLGNLLIIVLIKLDSHL-HTPMYLFLSNLSFSDLCFSSVTMPKMLHNMQSQDPS--IPYGGCLAQIYFLMAFGDMESFLLVVMAYDRYVAICFPLHYTSIMSPKLCTCLMLLLWILTTSHAMMHTLLAARLSFCENNVILNFFCDLFAVLKLSCSDTYINDLMILIFG-GLIFIIPFLLIVISYARIISSILKVPSTQG-IYKVFSTCGSHLSVVSLFYGTIIGLYLCPSGNNSTVKEIAMAMMYTVVTPMLNPFIYSLRNRDMKKALI---------RVICSKKISL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0U1RNJ4-1", "uniprot_id": "A0A0U1RNJ4_MOUSE", "id": "A0A0U1RNJ4-1", "name": "Olfactory receptor", "aln": "----------------------MIMK--------------NQTVITQFLLLGLPILPEHQHLFYALFLAMYLTTALGNLLIIVLVQLDSHL-HTPMYLFLSNLSFSDLCFSSVTMPKLLQNIQSQDPS--IPYAGCLAQTYFFMVFGDMESFLLVAMAYDRYVAICFPLHYTSIMSPKLCGCLMLLLWMLTTSHAMMHTLLAARLSFCENNVILNFFCDLFVLLKLACSDTYVNELMIFIMS-SLLIVIPFFLIVMSYARIIASILKVPSIQG-IYKVFSTCGSHLSVVTLFYGTIIGLYLCPSGNNSTVKGTVMAMMYTVVTPMLNPFIYSLRNRDMKRALI---------RVICSKKISL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VF79-1", "uniprot_id": "Q8VF79_MOUSE", "id": "Q8VF79-1", "name": "Olfactory receptor", "aln": "----------------------MIMN--------------NKTVISQFILLGLPIPQEYQHLYYALFLAMYLTTVLGNLIIIILIILDSHL-HTPMYLFLSNLSFSDLCFSSVTMPKLLQNMQSQDTS--ISYAGCLTQMYFLLVFGDLESILLLVMAYDRYVAVCFPLHYMSIMSPTLCVCLLVLSWVFTVLYSMLHTLLLSRLSFCEDNLIHHFFCDISALLKLACSDIHINELMIFIMG-GLVSIIPFLLIVVSYIQIVYSILKISSAHV-LHKIFSTCGSHLSVVSLFYGTIFALYLCPSANNSTVKEISMAMMCTVVTPMLNPFIYSLRNRDMRDALF---------GVLGKKKISL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TRX8-1", "uniprot_id": "Q7TRX8_MOUSE", "id": "Q7TRX8-1", "name": "Olfactory receptor", "aln": "----------------------MIIN--------------NQTAIPQFILLGLPILPEQQQMFYALFLAMYLTTVLGNLIIIILIRLDSHL-HTPMYLFLSNLSFSDLCFSSVTMPKLLQNIQSQDPS--ISYAGCLTQMYFFMVFANTENVLLVVMAYDRYVAICFPLHYTSIMSPKLCVSLVVLTWVFTVLYSMLHTLLLARLSFCEDNVITHFFCDISALLKLACSDTYINELMIFILG-TLDTVVPFLLIVVSYVQIVCSILKFSTKQG-IAKVFSTCGSHLSVVSLFYGTIIGVYLCPSANNSTVKEIVMALMYTVVTPMLNPFIYSLRNRDIKEALI---------RVLCKKQIPL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGT1-1", "uniprot_id": "Q8VGT1_MOUSE", "id": "Q8VGT1-1", "name": "Olfactory receptor", "aln": "----------------------MIKN--------------NQTVISQFLLLGLPIPPEHQHLFYALFLAMYLTTVLGNLIIIILIILDFHL-HTPIYLFLSNLSFSDLCFSSVTMPKLLQNMQSQDTT--ISYVGCLTQMYFPNVFANLENFLLMFMAYDRYVAICYPLRYTSIMSPILCVCMVFMSWLLTMLNSTLHTVLIVKLSFCEDNVIPHFFCDISAVLKLACSDIYINELTIFITG-AFIIVIPFLLIVVSYVQIVCSILKFSSTRG-IAKIFSTCGSHLSVVSLFYGTIIGLYLCPSTNNSTVKDTAMAMMYTVVTPMLNPFIYSLRNKDMKEALI---------RVLCKKEISL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SSP0-1", "uniprot_id": "Q5SSP0_MOUSE", "id": "Q5SSP0-1", "name": "Olfactory receptor", "aln": "----------------------MIMN--------------NKTVITQFILLGLPILPEYQHLFYALFLSMYLTTILGNLIIIILIQLDSHL-HTPMYLFLSNLSFSDLCFSSVTMPKLLLNMQSQDTS--IPYAGCLTQMYFSNLFGSLEIFLLVIMAYDRYAAICLPLHYTSIMSPKLCVCLVLLSWVISMLYSMLHTLLLARLSFCEDNVIPHFFCDISALLKLACSDIHINELMIFFLG-GPLTVIPFLLIVVSYIQIVFSILKISSTRA-IHKVFSTCGSHLSVVSLFYGTIIGLYLCPSANNFSVKKASITMMYTVVTPMLNPFIYSLRNRDIKEALV---------RVLIKK-ISL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGT3-1", "uniprot_id": "Q8VGT3_MOUSE", "id": "Q8VGT3-1", "name": "Olfactory receptor", "aln": "----------------------MIKN--------------NQTLFNQFLLLGLPIPAEHQQLFFALFLSMYLTTILGNLIIIILIRLDSHL-HTPMYLFLSNLSFSDLCFSSVTMPKLLQNMQSQDTS--ITYAGCLTQMYFFVLFGGLEIFLLVVMAYDRYVAICLPLHYTSIMSLKLCVCLVLLSWVISILNSMLHTLLLARLSFCEDNMIRHFFCDMSALLKLACSDIYINELMIFILG-GPLMVIPFLLIVMSYVQIIFSILKASSTRA-IYKVFSTCGSHLTVVSLFYGTIIGLYLCPSANNFTAKEASIAIMYTVVTPMLNPFIYSLRNRDIKEALI---------NVLIKK-IPL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGT2-1", "uniprot_id": "Q8VGT2_MOUSE", "id": "Q8VGT2-1", "name": "Olfactory receptor", "aln": "----------------------MTRR--------------NQTVISQFLLLGLPIPPEHQQLYYALLLSMYLTTVLGNLIIIILILLDSHL-HTPMYLFLSNLSFADLCFSSVTMPKLLQNMQSKVPS--IPYAGCLAQIYFFLYFGDLGNFLLVAMAYDRYVAICFPLHYMSIMSPRLCVSLVLLSWVLTTFHAMLHTLLMARLSFCEDNVIPHYFCDMSTLLKVACSDTHDNELAIFILG-GPIVVLPFLLIIVSYARIVSSIFKFPSFQG-IRKAFSTCGSHLSVVSLFYGTVIGLYLCPSANNTYVKETIMSLMYTMVTPMLNPFIYSLSNRDIKDALE---------KIMCKRQIPFFL-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGI1-1", "uniprot_id": "O1E16_MOUSE", "id": "Q8VGI1-1", "name": "Olfactory receptor 1E16", "aln": "----------------------MTER--------------NKTVISQFLLLGLPIPPEHQQLFYALFLVMYLTTVLGNLIIIILIILDSHL-HTPMYLFLSNLSFSDLCFSSVTMPKLLQNMQSQVPS--IPYAGCLAQIYFFLFFGDLGNFLLVAMAYDRYVAICYPLHYTTIMSPRLCVSLVVLSWVLTTFHAMLHTLLMARLSFCEDNVIPHYFCDMSALLKLACSDTRVNEVVIFIVA-SIFLVLPFALITMSYVRIVSSILKVPSSQG-IYKAFSTCGSHLSVVSLFYGTVIGLYLSPSSNNSTVKDTVMSLMYTVVTPMLNPFIYSLRNRDIKGALE---------RVFCKRKIQLNL-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGI2-1", "uniprot_id": "Q8VGI2_MOUSE", "id": "Q8VGI2-1", "name": "Olfactory receptor", "aln": "-------------------MQGTTER--------------NQTAISQFLLLGLPIPTEHQHLFYALFLAMYLTTVLGNLIIIILIHLDSHL-HTPMYSFLSNLSFSDLCFSSVTMPKLLQNMQSQDPS--IPYAGCLAQMYFFLFFADLESFLLVAMAYDRYVAICFPLHYMSIMSPRLCVSLVLLSWVLTTFHAMLHTLLMARLSFCEDNVIPHFFCDMSALLKLSCSDTYVNELVIFVMG-SLILVIPFVLILVSYARIVSSILKVPSARG-IRKAFSTCGSHLSVVSLFYGTVIGLYLCPSADNSTVKETVMAMMYTVVTPMLNPFIYSLRNRDMKGALI---------SVLCKKKILFCL-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TRX9-1", "uniprot_id": "Q7TRX9_MOUSE", "id": "Q7TRX9-1", "name": "Olfactory receptor", "aln": "----------------------MAEG--------------NQTVIFQFLLLGLPIPTEHQQLYYALFLLMYLTTVLGNLIIIILIRLDSHL-HTPMYLFLSNLSFSDLCFSSVTMPKLLQNMQSQDSS--ITYAGCLTQMYFFLLFGDLESFLLVAMAYDRYVAICFPLHYMSIMSPSLCVSLVLLSWVLTTFHAMLHTLLMARLSFCEDNVIPHFFCDMSALLKLSCSDTHVNELVIFVTG-GLILVIPFVLILVSYAQIVSSILKVPSARG-IRKAFSTCGSHLSVVSLFYGTIIGLYLCPSADNSTVKETVMAMMYTVVTPMLNPFIYSLRNRDMKGALA---------RVICKKKVFFCL-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TRX4-1", "uniprot_id": "Q7TRX4_MOUSE", "id": "Q7TRX4-1", "name": "Olfactory receptor", "aln": "----------------------MPGK--------------NQTVISRFILLGLPIPPEHQHLFYALFLAMYLTTVLGNLVIIVLIHLDSHL-HTPMYLFLSNLSFTDLCFSTVTMPNFLQNMQSQVSS--IPYAGCLAQMYFFLFFGDVESLLLVAMAYDRYVAICFPLHYTRIMSPNLCVSMVLLSWALTTLCAMLHTLLLTRLSFCKNNVIPHFFCDLSALLKLACSDIHINELMIMIIG-ALVVILPFLLIIVSYAHIVSSILKVPSTRG-IHKVFSTCGSHLSVVSLFYGSVIVLYLCPSSNNSTVKDTVMSMMYTVVTPMLNPFIYSLRNRDMKEALK---------RVLQKKIKLSSNYGNYISDVFIK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VEZ7-1", "uniprot_id": "Q8VEZ7_MOUSE", "id": "Q8VEZ7-1", "name": "Olfactory receptor", "aln": "----------------------MPGN--------------NQTIISQFLLLGLPIAPEYEHLFYALFLAMYLTTVLGNLIIIILIILDSHL-HTPMYLFLSNLSFSDLCFSSVTMPKLLQNMQSQDTS--IPYAGCLTQVYFFLFFAALENFLLVAMAYDRYVAICFPLHYASIMSPKLCVSLVLLIWVLTTLYAMLHTLLLTRLSFCENNVIPHFFCDLSALLKLACSDIHINELVILIIG-GLVVLLPFLLIIVSYARIISSILKVPSTRG-IHKLFSTCGSHLSVVSLFYGTIIGIYLGPSANNSTLKDIVMSMMYTVVTPMLNPFIYSLRNRDIKGALK---------KVFQKKSLL--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VEZ6-1", "uniprot_id": "Q8VEZ6_MOUSE", "id": "Q8VEZ6-1", "name": "Olfactory receptor", "aln": "----------------------MERG--------------NQTVVSEFLLLGLPIEPHQQDLFYALFLSMYLTTALGNLIIIILIHLDSHL-HTPMYLFLSNLSFSDFCFSSVTIPKLLQNMQSQVPS--IPYAGCLAQMYFFLLFADLESFLLVAMAYDRYVAICFPLHYTSIMSPKLCLCLVALSWLLTTVISLSHTLLMARLSFCANNVIPHFFCDMSALLKLACSDIQINKLMIFILG-GLVIIVPFLLIFSSYARIVSSILKVPSSRS-IRKAFSTCGSHLSVVSLFYGTIIGLYLCPSANNSTIKETVMAVMYTVVTPMLNPFIYSFRNQDIKGAFK---------KVFSKQMANFSLR----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGL0-1", "uniprot_id": "Q8VGL0_MOUSE", "id": "Q8VGL0-1", "name": "Olfactory receptor", "aln": "----------------------MRRD--------------NESTVSEFILLGLPIRAEDQGLYSALFLAMYLTTVLGNLLIILLIRLDSHL-HTPMYFFLSHLAFTDISFSSVASPKMVINMLTHSQS--ISYAGCVSQVYFFSFFADLESFLLTSMAYDRYVAICHPLHYSQIMSENLCVLLIVVSWTLSTANSLVHTLLLVQLSYFRNNTIPHYFCDLSTLLKLSSSDTTINELVILVLG-NMVITLPFICILVSYGHIGVTIMKIPSIKG-ICKALSTCGSHLCVVSLYYGAIIGLYFVPSSNNTSDKDAIVAMMYTMVIPMLNPFIYSLRNRDMKGALR---------NILSGRLWSQ-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGK4-1", "uniprot_id": "Q8VGK4_MOUSE", "id": "Q8VGK4-1", "name": "Olfactory receptor", "aln": "----------------------MRRD--------------NESTVSEFILLGLPIRAEEQGMYFALFLAMYLTTVLGNLLIILLIRLDSHL-HIPMYFFLSHLAFTDISFSSVTAPKMLVNMLTHSQS--ISYTGCVSQVYFFAIFADLDSFLLTSMAYDRYVAICHPLHYSQTMSQTLCVLLVLVSWALSIANALVRTLLLAHLSHFRDNTIPHYFCDLSDWLKLSSSDTTINELVILVLG-NVVITLPFICILVSYGHIGVTILKTPSIKG-ICKALSTCGSHLCVVSLYYGAIIGLYFVPSSNNTNDKDAIVAVMYTVVTPMLNPFIYSLRNRDMKGALR---------NILGRRLCS--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGK7-1", "uniprot_id": "Q8VGK7_MOUSE", "id": "Q8VGK7-1", "name": "Olfactory receptor", "aln": "----------------------MKRD--------------NESTVSEFILLGLPIRAEDQGLYSALFLAMYLTTMLGNLLIILLIRLDSHL-HTPMYFFLSHLAFTDISFSSVTAPKMLMNMLTHSQS--ISYAGCVSQMYFYIVFADLENFLLTSMAYDRYVAICHPLHYTTIMSQSLCLFLVVVSWALSSGNALVHTLLLAKLSHFRNNTVPHYFCDLSAMLKLSSSDTTINELLILTLG-TMVTIPPFICILVSYVRIGVTILRTPSIKG-ICKALSTCGSHLCVVSLYYGAIIALYFVPSSNNTNDKDVIVALMYTVVTPMLNPFIYSLRNRDMKGALR---------NVLSRRLCSQ-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGK9-1", "uniprot_id": "Q8VGK9_MOUSE", "id": "Q8VGK9-1", "name": "Olfactory receptor", "aln": "----------------------MRRD--------------NESTVSEFILLGLPIQPEDQGLYSALFLAMYLTTVLGNLLIILLIRLDSHL-HTPMYFFLSHLAFTDVSFSSVTAPKMLMNMLTHSQS--ISYAGCVSQVYFFSTFTDLDSFLLTSMAYDRYVAICHPLHYTTIMSQNLCVLLVVMSWVLSSANALVHTLLLARLSHFRNNTIPHYFCEPSALLSLSSSDTTINEMVILPLG-TLVITLPFICILVSYGRIGVTILRTPSIKG-ICKALSTCGSHLSVVCLYYGAIIGLYLVPSSNNTNDKDVIVAVIYSLVTPMVNPFIYSLRNRDIKGALR---------NILNRRLCPQW------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGK2-1", "uniprot_id": "Q8VGK2_MOUSE", "id": "Q8VGK2-1", "name": "Olfactory receptor", "aln": "----------------------MTEG--------------NESIVSEFILLGLPIQPEDQDLYSALFLAMYLTTVLGNLLIILLIRLDSHL-HTPMYFFLSHLAFTDISFSSVTAPKMLMNMLTHSQS--ISYAGCVFQVYFFLFFADLDNFLLTSMAYDRYVAICHPLHYTTMMSQNLCVLLVVVSWTLSTANALVHTLLLARLTHFRDNTISHYFCDLSTLLKLSSSDTTTNKLVILLLG-NVIITLPFICILVSYGLIAVTILKIPSMKG-ICKALSTCGSHLCVVSLYYGAIIGLYFVPSSNNTNVQDAIVAVMYNVVTPMLNPFIYSLRNQDMKGALR---------NILSRRLCLQ-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGK6-1", "uniprot_id": "Q8VGK6_MOUSE", "id": "Q8VGK6-1", "name": "Olfactory receptor", "aln": "------------------------MD--------------NESTVSEFILLGLPIRAEDQAVYSALFLVLYLTTVLGNLLIILLIRLDSHL-HTPMYFFLSHLAFTDISFSSVTAPKMLVNMLTHSQS--ISYAGCISQEYFFTVFAGIDSFLLTSMAYDRYVAICHPLHYITIMNQNLCVLLVVVSWALSSANCLVHTLLLACLSHFRNNTIPHYFCDLSTLLKLSSSDTTINQLVILVLG-NVVISLPFICILVSYGRIGVTIMKAPSIKG-ICKALSTCGSHLCVVSLYFGSIIGLYCVPSSNNINENNAIVSVMYTMVTPMLNPFIYSLRNRDIKRALK---------NILSRK-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGJ7-1", "uniprot_id": "Q8VGJ7_MOUSE", "id": "Q8VGJ7-1", "name": "Olfactory receptor", "aln": "----------------------MRMD--------------NESTVSEFILLGLPIRAKDQAVYSALILAMYLTTVLGNLLIILLIRLDPHL-HTPMYFFLSHLALTDISFSSVTVPRMLVNMLTQSQS--ISYTGCISQVYFFIVFGSIDSFLLPSMAYDRYVAICHPLHYTLIMNLNLCVLLVVVSWALSLVNALVHTLLLARLSHFRNNIIPHYFCDLSALLKLSSSDTSINELVILVLG-NVVITLPFICILVSYGYIGVTILKTPSTKG-IRKALSTCGSHLCVVSLYYGSVIGLYCVPSSNNTNDKDAIVAMMYTVVTPMLNPFIYSLRNRDMKRALR---------NILSRKK----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGK5-1", "uniprot_id": "O1J21_MOUSE", "id": "Q8VGK5-1", "name": "Olfactory receptor 1J21", "aln": "----------------------MMKS--------------NQSTVSEFILLGLPIQPEDQAVYFALFLAMYLTTVLGNLLIILLIRLDSHL-HTPMYFFLSHLAFTDISFSSVTAPKMLMNMLTHSQS--ISHAGCVSQIYFFLLFGCIDNFLLTSMAYDRYVAICHPLHYTTIMSQSLCVLLVMVSWAFSSSNGLVHTLLFARLSLFRDNTVHHFFCDLSALLKLSSSDTTINELVILTLA-VVVITVPFICILVSYGHIGATILRTPSIKG-ICKALSTCGSHLCVVSLYYGAIIGLYFFPSSNNTNDKDVIVAVLYTVVTPMLNPFIYSLRNRDINGALR---------KTLSRRLCSH-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGK3-1", "uniprot_id": "Q8VGK3_MOUSE", "id": "Q8VGK3-1", "name": "Olfactory receptor", "aln": "----------------------MKSTR-------------NQSSASEFILLGLPIQPEEQGMYYALFLATYLTTVLGNLLIILLIRLDSHL-HTPMYFFLSHLAFTDISFSSVTAPKMLMNMLIHSQS--ISYAGCISQVYFFLFFADLDSFLLTSMAYDRYVAICHPLHYTRIMSQSICILLVIESWFLSFAGALVHTILLARLSFFRGNTVHHFFCDLSALIKLSSSDTSINELVILVVG-SLVITVPFVCILVSYGRIGATILKTPSIKG-ICKALSTCGSHLSVVSLYYGAIIGLYFVPSSNDTNDKDVIVAVMYTMVTPMLNPFIYSLRNRDMKGALR---------NMLARATSSM-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFP8-1", "uniprot_id": "Q8VFP8_MOUSE", "id": "Q8VFP8-1", "name": "Olfactory receptor", "aln": "----------------------MKRD--------------NQSMVSEFILLGLPIRPEEQGMYYALFLTMYLTTVLGNLLIILLIRLDSHL-HTPMYFFLSHLAFTDISFSSVTVPKMLRNMHIHDPS--IPYAECIAQMYFFILFTDLDNFLLTSMAYDRYVAICHPLHYTTIMREELCILLVAISWILSCVSALSHTLLLARLSFCADNTISHFFCDLAALLKLSCSDISLNELVIFTVG-TTVITLPLICILISYGHIVATILKVSSNKG-ICKALSTCGSHLSVVSLYYGTIIGVYFIPSSFTSTDKGIVASVMYTVVTPLLNPFIYSIRNRDMKEALK---------KLFNRASIST-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q60879-1", "uniprot_id": "OR1J1_MOUSE", "id": "Q60879-1", "name": "Olfactory receptor 1J1", "aln": "----------------------MRLK--------------NHSSVSEFLLLGFPIRPEQGGIFFSLFLAMYLITVLGNLLIILLIRLDSHL-HTPMYFFLSHLAFTDISFSSVTVPKMLTKVQNQPIP--ITYEECVSQTYFFIFFADLDSFLITSMAYDRYMAICHPLHYITIMSQSRCAMLVAVSWVIASACALLHSLLLDQLSFCADHTVPHFFCDLGALLKLSCSDTSLNQLVIFTAG-LAAIMLPFLCILISYGRIGFTILQVPTTKG-ICKALSTCGSHLSVVALYYGSIIGLYFLPPSNSKINNNIVASVMYTVVTPMLNPFIYSLRNKDMKGALK---------KLLSKKTEFSK------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TRY6-1", "uniprot_id": "Q7TRY6_MOUSE", "id": "Q7TRY6-1", "name": "Olfactory receptor", "aln": "----------------------VRRE--------------NQSTVFEFLLLGLPIRPEHQNVFFTMFLAMYLTTVLGNLLIILLIRLDPHL-HTPMYFFLSHLAFSDISLSSITVPKMLMNIQAQHHS--ISYKGCISQMYFFILFVCLDNFLLAAMAYDRYVAICHPLHYITVMREELCVCLVAGSWFFSCVHALLHTLLLIQLSFCASNTVPNFFCDLTALLKLSCSDISLNKLVIFTEG-GLLFILPLSSIMGSYILIGRTALKAPSTKR-FIKTFSTCGSHLLVVSLYYGTLAGEYFFSSFQNSSDKDIVASVIYTVVTPLLNPFIYSLRNSDIKQALE---------IVVTKINCFK-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TRX1-1", "uniprot_id": "Q7TRX1_MOUSE", "id": "Q7TRX1-1", "name": "", "aln": "----------------------MREE--------------NESSTTDFTLLGVTRQREQEYFFFILFLFIYPITVFGNMLIILAIHSDTRL-HNPMYFFLANLSLVDIFFSSVTIPKMLANHLLGSKA--ISFGGCMAQMYFMIGLANTDSYILAAMAYDRAVAISRPLHYATIMSPQLCVLLVAGSWVIANANALPHTLLTARLSFCGNKDVANFYCDITPLLQLSCSDIRFN-VKMMYLG-VGVFSVPLLCIIISYVRVFSTVLRVPSTKG-FLKALSTCGSHLTVVSLYYGTVMGMYFRPLTSYS-LKHALITVMYTAVTPMLNPFIYSLRNRDMKAALK---------KLFHCPSSSSSLM----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TRX2-1", "uniprot_id": "Q7TRX2_MOUSE", "id": "Q7TRX2-1", "name": "", "aln": "----------------------MREE--------------NESSTIDFTLLGVTRQREQEYFFFILFLFIYPITVFGNMLIILAIHSDTRL-HNPMYFFLANLSLVDIFFSSVTIPKMLANHLLGSKA--ISFGGCMAQMYFMISLGNTDSYILAAMAYDRAVAISRPLHYATIMSPQLCVLLVAGSWVIANANALPHTLLTARLSFCGNKDVANFYCDITPLLQLSCSDIRFN-VKMMYLG-VGVFSVPLLCIIISYVRVFSTVLRVPSTKG-FLKALSTCGSHLTVVSLYYGTVMGMYFRPLTSYS-LKHALITVMYTAVTPMLNPFIYSLRNRDMKAALK---------KLFHCHSSSSSLM----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15619-1", "uniprot_id": "OR1C1_HUMAN", "id": "Q15619-1", "name": "Olfactory receptor 1C1", "aln": "----------------------MEKRN--------------LTVVREFVLLGLPSSAEQQHLLSVLFLCMYLATTLGNMLIIATIGFDSHL-HSPMYFFLSNLAFVDICFTSTTVPQMVVNILTGTKT--ISFAGCLTQLFFFVSFVNMDSLLLCVMAYDRYVAICHPLHYTARMNLCLCVQLVAGLWLVTYLHALLHTVLIAQLSFCASNIIHHFFCDLNPLLQLSCSDVSFNVMIIFAVG-GLLALTPLVCILVSYGLIFSTVLKITSTQG-KQRAVSTCSCHLSVVVLFYGTAIAVYFSPSSPHMPESDTLSTIMYSMVAPMLNPFIYTLRNRDMKRGLQ---------KMLLKCTVFQQQ-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VFD9-1", "uniprot_id": "Q8VFD9_MOUSE", "id": "Q8VFD9-1", "name": "Olfactory receptor", "aln": "----------------------MNCS-----------------QAPTFILLGLSSDAEKWQPLFSIFLVLYLLGLLGNLLLLLAIGTDVHL-HTPMYFFLSQLSLVDLCFITTTAPKMLEALWTGDGS--ISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLLYPLLMTPCRCRVLVSGSWGVAHCVSLTHTLLFSKLYFHNNQEIPHFFCDFGPLLLLSCSDTYLNESLMMALS-GLLAISAFLCIVSSYGCIFYAVAKVPSAQG-KRKALATCSSHLSVVLLFYSTVFATYLKPPSSSHSSQEVVAAVMYTLVTPTLNPFIYSLRNKDVKSSLR---------RILNMVKSQD-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFE4-1", "uniprot_id": "Q8VFE4_MOUSE", "id": "Q8VFE4-1", "name": "Olfactory receptor", "aln": "----------------------MNCS-----------------QAPTLILLGLSSDAEKWQPLFSIFLVIYLLGLLGNLLLLLAIGTDVHL-HTPMYFFLSQLSFVDLCFITTTAPKMLEALWTGDGS--ISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLRYSALMTPFRCGVLVSGSWGVTNCVSLTHTLLLSKLYFHTNQEIPHFFCEFGPLLLLSCSDTHLNKILVIILV-GILGISAVLCIVSSYGCIFYAVAKVPSAQG-KRKALSTCSSHLSVVLLFYSTVFATYLKPPSSSRSSEEVVAAVMYSLVTPTLNPFIYSLRNKDVKSSLR---------RILNME-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFW9-1", "uniprot_id": "Q8VFW9_MOUSE", "id": "Q8VFW9-1", "name": "Olfactory receptor", "aln": "----------------------MENST----------------EVTEFILTGLTDNPELQIPLFIVFLLIYLSTVLGNLGMVGLILLDSHL-HTPMYLFLSHLSLVDFGYSSAVTPKVMPGLLSIDKT--ITHNACGTQFFFFVSFITTESFLLAAMAYDRYAAVCKPLQYTTTMTTNTCACLTIGSYVCGVLNSSIHTGNIFRLSFCKFNVIDHFFCDAPPLLALSCSDTSVSEMVILFVV-GFNDIFSIVVIPISYLFIFITILRMRSSEG-RQKAFSTCASHLTVVFIFYGSGIFMYLQPSSSHTMGTDKMASVFYTMIIPMLNPLVYSLRNKEVKSAFK---------KAVEKAKISLAFTF---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFX1-1", "uniprot_id": "Q8VFX1_MOUSE", "id": "Q8VFX1-1", "name": "Olfactory receptor", "aln": "----------------------MENST----------------EVTEFILAGLTDDPKLQIPLFIVFLLIYLSTVLGNLGMVGLILLDSHL-HTPMYLFLSHLSLVDFGYSSAVTPKVMSGLLSIDKT--ISHNTCGTQFFFFVGFITTESFLLAAMAYDRYAAVCKPLHYTTTMTTNTCACLTIGSYVCGFLNSSIHTGNIFRLSFCKFNVIDHFFCDAPPLLALSCSDTYISETVIFFVV-GFNALFSIVVITISYLLIFITILRMRSSEG-RHKAFSTCASHLTAVSIFYGTVIFMYLQPSSSHTMGTDKMASVFYTMVIPMLNPLVYSLRNKEVKGAFK---------KAVGNAKSALTFLF---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFX4-1", "uniprot_id": "Q8VFX4_MOUSE", "id": "Q8VFX4-1", "name": "Olfactory receptor", "aln": "-------------------MTIMKNRT----------------EVTEFILLGLTNDPGMQLPLFITFLLIYTITVVGNLGMILLIVLDSRL-HTPMYIFLGNLSLVDFCYSSAVTPTVMTELLIGKKV--ISYNDCAAQMFFFGAFATVENYLLASMAYDRYAAVCKPLHYATIMTKSVYTRIITASYGISFMSASIHIADIFTLSFCKSNVIHHFFCDVPAIMALTCFDNQVRELVLLYIE-SLDVFFALIVICTSYMLIFVTILKMHSASG-HHKAISTCASHFTAVSIFYGTVIFMYLQPSSNHSMDIDKVTSVFYTMVIPMLNPLVYSMRNKEVKNAFI---------KLILH------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFX3-1", "uniprot_id": "Q8VFX3_MOUSE", "id": "Q8VFX3-1", "name": "Olfactory receptor", "aln": "-------------------MTIMKNRT----------------EVTEFILLGLTNDPGLQLPLFITFLLIYTITVVGNLGMILLIVLDSRL-HTPMYIFLGNLSLVDFCYSTAVTPTVMNGLLIGNKV--ISYNDCAAQMFFFGAFATVENYLLASMAYDRYAAVCKPLHYATIMTKSMYTWLITGSYVISFTNSSIHIADIFTLSFCKSNVIHHFFCDVPAIMALTCFDNQVREHVLLYIE-SLNVFFALIVICTSYMLIFVTILKMHSASG-HHKAISTCASHFTAVSIFYGTVIFMYLQPSSNHSMDTDKVTSVFYTMVIPMLNPLVYSLRNKEVKNAFI---------KLILHY-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFK3-1", "uniprot_id": "Q8VFK3_MOUSE", "id": "Q8VFK3-1", "name": "Olfactory receptor", "aln": "-------------------MSLMENNT----------------KVTEFLLLGLTNDPELQLPLFLIFLLIYTITLVGNLGLILLIVLDSCL-HTPMYIFLGNLSLVDFCYSSAVTPSVMTELLIGKKV--ISYNDCAAQTFFFVAFCTVENYLLASMAYDRYAAVCKPLHYASTMTTRVCIYLSIGSYVCGFLNASINTGNTFSLFFCRYNMIHHFFCDIPAVMVLSCSDRYFSELLLVYVV-SFSIFFALLVICISYIFIFITIAKMHSSAG-YGKAAPTCASHFTAVSIFYGTVIFMYLLPSSSHSMDTDQIASVFYTMIIPMLNPLVYSLRNKEVKSAFT---------KIFQVAKQSVMLYF---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFW5-1", "uniprot_id": "Q8VFW5_MOUSE", "id": "Q8VFW5-1", "name": "Olfactory receptor", "aln": "-------------------MSLMENNT----------------DVTQFLLLGLTDDPGLQFPLFITFLLIYTITLVGNLGMILLIVLDSRL-HTPMYFFLGNLSLVDFCYSSAVTPTVMTG-LIGEKI--ISYNDCAAQMFFFVAFATVENYLLASMAYDRYAAVCKPLHYATTMTANVCICLCIGSYTCGFLNASIHIGDTFSLSFCRSNVVHHFFCDIPAVMVLSCSDRHVSELVLVYVV-SFNIFFALSVIWISYIFIFITICKMHSSSG-YRKAISTCASHFIAVSIFYGTIIFMYLQPSSSHSMDTDKIASVFYTMIIPMLNPLVYSMRNKEVKSAFT---------KVLQVAK----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TQR2-1", "uniprot_id": "Q7TQR2_MOUSE", "id": "Q7TQR2-1", "name": "Olfactory receptor", "aln": "----------------------MENNT----------------EVTHFLLLGLTDDPELQLPLFMILLIIYTITLVGNLGKILLIFLDSCL-HTPMYFFLGNLSLVDFCYSSDVTPKVMSGLLKGDKV--ISYNGCAAQMFFFVAFATVENFLLASMAYDRYAAVCKPLHYATTMTSGVCVCLSIGSYACGFLIASIHIGDTFNLSFCRSNVVHHFFCDIPAVMILSCSDRHVSELVLFYVG-SFSIFFSVLVICISYIFIFITIFKMHSDAG-YGKAVSTCAAHFTAVSIFYGTGIFMYLQPSSSHSMDTDKITSVFYTMIIPMLNPLVYSMRNKEVKRAFT---------NVFHKAK----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFW1-1", "uniprot_id": "Q8VFW1_MOUSE", "id": "Q8VFW1-1", "name": "Olfactory receptor", "aln": "---------------------MMENQT----------------EVTEFILLGLTDDPELQIPLFITFLAIYTITVVGNLGMILLILMDSRL-HTPMYFFLGNLSLVDFCYSSAVTPKVMSGFLIGDKV--ISYNDCAAQMFIFAAFITVENYLLASMAYDRYAAVCKPLHYTTTMTTSVCTWLIIGSYVIGFMNASIHIGDTFHLYFCESNVVHHFFCDIPAVMVLSCSDRYASELVLVYIV-SFHIFFAFIVIWISYVFIFVTIVKMQSAAG-HHKAISTCASHFTAVSIFYGTSIFMYVQPSSNHSMDTDKIASVFYTMVIPMLNPLVYSLRNKEVKSALK---------KIILQTT----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TQR3-1", "uniprot_id": "Q7TQR3_MOUSE", "id": "Q7TQR3-1", "name": "Olfactory receptor", "aln": "-------------------MTPLKNWT----------------EVTHFLLLGLTDDPGLQLPLFIIFLLIYIFTLVGNLGLILLILLDSRL-HTPMYFFLGNLSLVDVFYSSAITPKVMAGLLLGDKI--ISYNSCAAQMFVFATFATVENYLLASMAYDRYAAVCKPLHYATTMTPSVCMCLIMGCYVLGFLSVSVYLGDTFSLSFCKSNVVHHFFCDMPALMALSCSDRHINELVLIYLA-SFTLFFALIIILVSYTIIFITILNMHTGAG-LQKAISTCASHFIAVFIFYGTTIFMYLQPSSRHSMDTDKIVSVFYTMVIPMLNPLVYSLRNKEVKSAFM---------KWILKEK----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFW4-1", "uniprot_id": "Q8VFW4_MOUSE", "id": "Q8VFW4-1", "name": "Olfactory receptor", "aln": "-------------------MTSLNNLT----------------EVTHFLLLGLTDDPGLQLPLFIIFLLIYIITLVGNLGMILLILLDSRL-HIPMYFFLANLSLVDVIYSSAVTPKVMAGLIIGDNL--ISYNECAAQMFFFAAFATVENYLLTSMACDRYAAVCKPLYYATTMTPSVCMCFIMGCYALGFLNASVYLGNTFSLSFCKSNVVHHFFCDMPAIMALSCSDRHVNELVLIYQA-SFIIFFALIIILISYIIIFITILKMHSEAG-VQKALSTCASHFTAVFIFYGTTIFMYLQPSSRHAMDTDKIVSVFYTMVIPMLNPLVYSLRNKEVKSAFM---------KVVLKEK----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VEV7-1", "uniprot_id": "Q8VEV7_MOUSE", "id": "Q8VEV7-1", "name": "Olfactory receptor", "aln": "-------------------MTLVKNWT----------------YVTEFILLGLTDDPGLQLPLFVIFLLIYIITLVGNLGMILLIFLDSQL-HIPMYFFLGNLSLVDVCYSSAVTPKVIAGLLIGDKF--ISYNDCAAQMFFFAAFATVENYLLASMAYDRYVAVCKPLHYTTTMTSNVCICLIMGCYGFSFLNVSVYLGDTFSLSFCNSNVVHHFFCDMPAIMALSCSDKHVNELVLIYLA-SFNIFVAFIMIIVSYLIIFITILNMRSRAG-VQKALSTCVSHLTAVFIFYGTIIFMYLQPSSRHAMDTDKIVSVFYTMVIPMLNPLVYSLRNKEVKSAFM---------KIVLKEKSL--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFX0-1", "uniprot_id": "Q8VFX0_MOUSE", "id": "Q8VFX0-1", "name": "Olfactory receptor", "aln": "----------------------MENRT----------------EVRCFILVGLTNDPSLQLPLSITFLLIYIITLIGNLGLILMILLDSRL-HTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLTGDKI--MSYNACASQMFFFANFGDVENYLLASMAYDRYVAVCKPLHYATTMTTHMCASLVIGCYICGFLSASIYTMDALSLSFCESNVIHHFFCDVLAVMIVSCSDSHVNELILIYVV-SFNMFFALIIILISYMFIFTNILKIHSSAG-YHKAVSTCASHFTAVSIFYGTIIFMYLQPSSSHTMDTDKIASVFYTMVICMLNPLVYSLRSKDVKSAFT---------KIVLRSK----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFW2-1", "uniprot_id": "Q8VFW2_MOUSE", "id": "Q8VFW2-1", "name": "Olfactory receptor", "aln": "----------------------MENRT----------------EVRCFILVGLTNDPGLQLPLFITFLLIYIITLIGNLGLILLILLDSRL-HTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLMGDKI--MSYNACASQMFFFANFADVENYLLVSMAYDRYVAVCKPLHYATTMTTHMCVCLLIGCYICGFLNASIYTVDALSLSFCESNVVHHFFCDVLAVMIISCSDRHVNELIFVYVA-SFNIFFALILIIISYTFIFTNILKLQSAAG-YRKAFFTCASHFTAVSIFYGTIIFMYLQPSSSHSMDTDKIASVFYTMVIPMLNPLVYSLRNKDVKSAFT---------KIILRSG----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFV9-1", "uniprot_id": "Q8VFV9_MOUSE", "id": "Q8VFV9-1", "name": "Olfactory receptor", "aln": "----------------------MENRT----------------EVTWFILVGLTNDSQLQLPLFITFLLIYTVTFVGNLGLILLILLDSRL-HTPMYIFLSNLSLVDFCYSSTITPKVIAGILTGDKI--MSYNACASQMFFFANFANVENYLLVSMAYDRYAAVCKPLHYATTMTKRVCASLVIGCYICGLLNASIYTMDALSLSFCESNVVHHFFCDVLAIMTTSCSDRHVNELILVYLA-SFNVFFALILILISYMFIFTNILKMHSASG-YCKAISTCASHLTAVFIFYGTIIFMYLQPSSHHSMDTDKIASVFYTMIIPMLNPLVYSLRNKDVKSAFT---------KIVLRSG----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1L1SSD5-1", "uniprot_id": "A0A1L1SSD5_MOUSE", "id": "A0A1L1SSD5-1", "name": "Olfactory receptor", "aln": "----------------------MENGT----------------EMVRFILMGLTDDPDLQLPLFITFLLIYIITLVGNLGLILLILLDSQL-HTPMYIFLSNLSLVDFCYSSTVTPKVMAGFIIGDKM--MSYNACASQMFFFANFANVENYLLASMAYDRYAAVCKPLHYATTMTTRVCACLVISCYICGFLNASIYTVNALYLTFCELNVVHHFFCDIPAVMIASCSHRHANDMVLISVA-SFNIFFALILILISYTFIFTNILKMHSNSG-YRKALSTCASHFTAVSIFYGTIIFMYLQPRSSHSMDTDKIASVFYTMVIPMLNPLVYSLRNKDVKSAFT---------KIVLRSR----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFW8-1", "uniprot_id": "Q8VFW8_MOUSE", "id": "Q8VFW8-1", "name": "Olfactory receptor", "aln": "----------------------MENRT----------------EVTEFILLGVTNAPALQTPLFILFTLIYFINMTGNLGMLVLILWDSRL-HTPMYIFLGNLSLVDIFYSSAVTPTVVAGLLVGNQA--ISYNACAAQMFLFVVFATAENFLLAAMAYDRYAAVCKPLHYTTTMTPTTCACLTMACYAGGFLNSSIHTGDTFRLYFCKSNVVHHFFCDVPAVMVLSCSDRHISEMVLLYGA-SFVICSALLVILISYIFIFITIFKMRSAAG-YQKAMSTCVSHFTAVSIFYGTLIFMYLQPSSSHSMDTDKIVSVFYTMVIPMLNPVVYSLRNKEVKSAFK---------KVVEKAKYTLGF-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFX5-1", "uniprot_id": "Q8VFX5_MOUSE", "id": "Q8VFX5-1", "name": "Olfactory receptor", "aln": "----------------------MENCT----------------KVREFILLGLTDDPGLQVSLCIMFTLIYLIDVVGNTGLIMLVLMDSHL-HTPMYFFLCNLSFVDLGYSSAVTPMVISEFFIVSKV--VSYNACAAQMFFFVGFATGENYLLASMAYDRYVAVCKPLHYSTRMTTSVCICLNIVSYICGFLNAIFHVGDIFSLSFCKSNVVHHFFCDVPAVLALSCSDIHLSEVILVFLS-TFNVFFALLIISVSYLFIFITVLKMKSDQG-HQKALSTCASHLTVVSIFYSTVIFMYLQPSSSHSMDADKVASMFYTMIIPTLNPLVYSLRNKEVNNAFK---------KVVERAKIFM-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VFX2-1", "uniprot_id": "O5B21_MOUSE", "id": "Q8VFX2-1", "name": "Olfactory receptor 5B21", "aln": "-------------------MTSMENIT----------------EVTEFILLGLTDDPNLQVPLLLIFLFIYLVTLIGNGGMMVIIFSDSHL-HTPMYFFLSNLSFVDLGYSSAVAPKMVAALQSGNKV--ISYNGCAAQFFFFVGFATVECYLLASMAYDRHAAVCRPLHYTTTMTTGVCTILTIGSYTCGFLNASIHAADTFKLSFCGSNKINHFFCDIPPLLALACSSTHISKLVVFFVV-GFNVFFTLLVIIISYFFIYIAIQNMKSSEG-RKKAFSTCASHLTAVSIFYGTIIFMYLQPSSGQSMDTDKIASVFYTVVIPMLNPLIYSLRNREVKSALW---------KILNRFYPASFSVSRK-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VGU2-1", "uniprot_id": "Q8VGU2_MOUSE", "id": "Q8VGU2-1", "name": "Olfactory receptor", "aln": "----------------------MRNHS----------------TVPEFILLGLSADAQVQALLFVLFLVIYLLTLMGNLMLLLVVKVDRHL-HTPMYFFLGQLSFLDLCHSSVSVPKLLENLLSVKKT--ISVEGCLAQVFFVFATGGTESCLLAVMAYDRYVAISSPLLYGQVMSRQLCAGLVWGSWSLAFLDAFINILVALNLDFCEAQNIHHFICELPSLYPLSCSDVSASFTTLLCSS-FIHFFGNFLLILLSYIRILLTILGISSASG-RSKAFSTCSSHLTAVSFFYGSGLLRYLMPNSGSTQEL--IFSLQYSVITPMLNPLIYSLKNKEVKAAVR---------RTVTKYLQCFK------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TS17-1", "uniprot_id": "Q7TS17_MOUSE", "id": "Q7TS17-1", "name": "Olfactory receptor", "aln": "----------------------MRNFS----------------VVSEFILLGLSDDAQVQALLFVAFLVIYVLTLTGNTMILLVIRVDAHL-RSPMYFFLGHLSFLDLLYSSVSTPKMLENLVSETKT--IPVKGCLAQAFFVFAIGGTEALLLAVMAYDRYAAICHPLLYGQMMNDWFCQVLVWGSWILAILNSLINTLLAVSLDFCHYGTIHNYNCEFPSLFPLSCSDVSTNATAIVCTF-VIHASGTFLLVVCSYGCIFSTILNMSSTRG-RSKAFSTCSSHLTIVTLYFGSACLRYVMPTSGSPMET--FFSLQYSVITPMLNPFVYSLKNKEVKMAMR---------KLLARCCQHFGEVDQRHRVKS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VET6-1", "uniprot_id": "Q8VET6_MOUSE", "id": "Q8VET6-1", "name": "Olfactory receptor", "aln": "--------------------MAWSNHS----------------VITEFVLTGLSDDPLIQALLFALFLGIYVLTMTGNLTMLLVITADSHL-HTPMYFFLSNLSFLDLCFSSVTVPKLLKDLLSAKKT--ISVEGCLAQVFFVFITAGTEAFLLSMMAYDRYAAVCHPLLYGQMMSNELCLKLVLLSWGLASLSSVVIVLLAVNLDFCEAYTIHHYTCELPSLFPLSCSDISINVDILICST-LLHGLGTFLPIFFSYARIVSTVLSMESTTG-RSKAFNTCSSHLIAVVLFFGSGLIRYLMPTSGSSLDL--LSSLQYSAVTPMLNPLIYSLKNQEVKAAVR---------RTLGKCLRYLE------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q90426-1", "uniprot_id": "Q90426_DANRE", "id": "Q90426-1", "name": "", "aln": "----------------------MDNQT---------------FRSSTLLMEGLQVANQYRQLAFIFVLIAYIFIMIFNIGLLIQISSEKSL-HQPMYILLCNLPLNDVFGTTLLLPRLLRNILLEPSERYITYVECVIQAFFGHLYGTTCHTILMIMAFDRYVAICNPLRYPAVMTSNMVVHLSAAAWGVAVVLVGILIGLTVRLSFCR-SVIENPFCDNASLFKLSCESTAINNIYGLSFT-VVLLTSSLGSIALTYLRIAIVCFKSKNKAT-NSKAIKTCSTHLAVYLIMMVSGLTTITLHRFPELSDSRKLSSIIKHIVPPCLNPIIYGLQVKEIRQRLF---------KLISKSKVNFM------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : * *:* :: *. * * : * * : : * *: *: * : : : *. . :* : *. . .** * : : . ", "identical_positions": 18, "similar_positions": 25, "identity": "4.8%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010319-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q92997-1", "uniprot_id": "DVL3_HUMAN", "id": "Q92997-1", "name": "Segment polarity protein dishevelled homolog DVL-3", "aln": "MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPSYKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVSWLVSAEGSHPDPAPFCADNPSELPPPMERTGGIGDSRPPSFHPHAGGGSQENLDNDTETDSLVSAQRER----PRRRDGPEHAT-RLNGTAKGERRREPGGY---DSSSTLMSSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRR-HKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAAWVSHTAAMTGTFPAYGMSPSLSTITSTSSSITSSIPDTERLDDFHLSIHSDMAAIVKAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGDLCGNMANLSLHDHDGSSGASDQDTLAPLPHPGAAPWPMAFPYQYPPPPHPYNPHPGFPELGYSYGGGSASSQHSEGSRSSGSNRSGSDRRKEKDPKAGDSKSGGSGSESDHTTRSSLRGPRERAPSERSGPAASEHSHRSHHSLASSLRSHHTHPSYGPPGVPPLYGPPMLMMPPPPAAMGPPGAPPGRDLASVPPELTASRQSFRMAMGNPSEFFVDVM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61062-1", "uniprot_id": "DVL3_MOUSE", "id": "Q61062-1", "name": "Segment polarity protein dishevelled homolog DVL-3", "aln": "MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPSYKFFFKSMDDDFGVVKEEISDDNAKLPCFNGRVVSWLVSAEGSHPEPAPFCADNPSELPPSMERTGGIGDSRPPSFHPHASGGSQENLDNDTETDSLVSAQRER----PRRRDGPEHAA-RLNGTTKGERRREPGGY---DSSSTLMSSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRR-HKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAAWVSHTAAMTGTFPAYGMSPSLSTITSTSSSITSSIPDTERLDDFHLSIHSDMAAIVKAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGDLCGNMANLSLHDHDGSSGASDQDTLAPLPHPGAAPWPMAFPYQYPPPPHPYNPHPGFPELGYSYGGGSASSQHSEGSRSSGSNRSGSDRRKEKDPKAGDSKSGGSGSESDHTTRSSLRGPRERAPSERSGPAASEHSHRSHHSLTSSLRSHHTHPSYGPPGVPPLYGPPMLMMTPPPAAMGPPGAPPGRDLASVPPELTASRQSFRMAMGNPSEFFVDVM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B8JMI2-1", "uniprot_id": "B8JMI2_DANRE", "id": "B8JMI2-1", "name": "", "aln": "MGETKVIYHLDDQETPYLVKLPIPAERVTLLDLKNALKKPNYKFFFKSMDDDFGVVKEEITDDNAKLPCYNGRVICWLVSSDGSHSDGCS-VAESQSERPPSHERSQGIGDSRPPSFHPKAAG-SRHGVDDETETDSVVSHRRDRDRDRSRRKHSHEHSGGKQNGYSRGGRGMDLGGYDICDSRSSLMSSELESSSCFDSD-DGSTSRFSSVTEQSGSSKLMTKKPRRRRRKTRAQQMERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDINFENMCNDDAVRVLREIVHKPGPVSLTVAKCWDPNPNSCFALPRSEPIRPIDPAAWVSHTAAMTGVYPPYGMSPSMSTVTSTSSSISSSIPETERFDDYHLSVHSDMATVAKAMACPDSGLEVRDRMWLKITIANAFIGSDVVDWLFHHVEGFTDRREARKYASNLLKAGFIRHTVNKITFSEQCYYIFGDLSGNMAHLSLQDHDGSSGASDQDTLAPLLHPAEAPWPAAFPYQYP------AAHSHLEEAG----GGSAGSQQSEGS--SGSNCSWS--RTEGKTAAGDFRLGG-GSEMGDAHEFDFR--RDRAPSERSGVPPSEGSVRSSRSHSYSLK--------------------------QGSARGGPGSPSGRHLAHIPPELTGSRRSCNTANG---EFFVDIM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:*****.**********:******* *:*..*::*.*******************:********:****:.****::***.: .. *:. ** **. **: ************:*.* *:..:*::*****:** :*:* .**:.. **: : ** ::* * : *** ** *:*******::* **** *.******* ****.:*:** : :***** :..::**************************************************************************:******.*****************::*********.*..**:************************.:*.******:**:*******:****:***:**:***:*****::.****.*:***************.************:*:*******************************************.****:***:***************** **. **** ******* .*. : * * ****.**:**** **** * * *.* .. *** : ** *** ..: . .:* *:******** ..** * ** :* : **: :* * **:*.**.** :*****.**:* . * * *****:*", "identical_positions": 498, "similar_positions": 117, "identity": "68.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010319-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35260-1", "uniprot_id": "NACC1_RAT", "id": "O35260-1", "name": "Nucleus accumbens-associated protein 1", "aln": "MAQTLQMEIPNFGNSILECLNEQRLQGLYCDVSVVVKGHAFKAHRAVLAASSSYFRDLFNSSR----SAVVELPAAVQPQSFQQILTFCYTGRLSMNMGDQFLLIYTAGFLQIQEIMEKGTEFFLKVSSPSCDSQGLHPEEAPSSEPQSPVAQILG-----------------WPACSTPLPLVSRVKTEQ-ELD--SVQCTPMAKRLWDSSQKEAG---GSGGNNGSRKMAKFSTPDLAPNRMPQPVS------VATATAAVA---------VVAVGGCVSGPSMSERTSPGTSSAYTSDSPSSYHNEEDEEEDAGEEGTDEQYRQICNMYTMYSMLNVGQTV-EKVEALPEQVVLESHSRIRVRQDLASLPAELINQIGNRCHPKLYDEGDPSEKLELVTGTNVYITRAQLMNCHVSAGTRHKVLLRRLLASFFDRNTLANSCGTGIRSSTNDPRRKPLDSRVLHAVKYYCQNFAPNFKESEMNAIAADMCTNARRVVRKSWLPKTKPLHLVEGDNYSSFISDTGKIEPDMMSMEHSFETASHDG-----EAGPSAEVLQ-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TSZ8-1", "uniprot_id": "NACC1_MOUSE", "id": "Q7TSZ8-1", "name": "Nucleus accumbens-associated protein 1", "aln": "MAQTLQMEIPNFGNSILECLNEQRLQGLYCDVSVVVKGHAFKAHRAVLAASSSYFRDLFNSSR----SAVVELPAAVQPQSFQQILTFCYTGRLSMNMGDQFLLIYTAGFLQIQEIMEKGTEFFLKVSSPSCDSQGLHPEEAPSSEPQSPVAQTLG-----------------WPACSTPLPLVSRVKTEQ-ELD--SVQCTPMAKRLWDSSQKEAG---GSGGNNGSRKMAKFSTPDLALNRMPQPLS------MATATAAVA---------VVAVGGCVSGPSMSERTSPGTSSAYTSDSPSSYHNEEDEEEDAGEEGTDEQYRQICNMYTMYSMLNVGQTA-EKVEALPEQVVLESRSRIRVRQDLASLPAELINQIGNRCHPKLYDEGDPSEKLELVTGTNVYITRAQLMNCHVSAGTRHKVLLRRLLASFFDRNTLANSCGTGIRSSTNDPRRKPLDSRVLHAVKYYCQNFAPNFKESEMNAIAADMCTNARRVVRKSWLPKTKPLHLVEGDNYSSFISDTCKIEPDMMSMEHSFETASHDG-----EAGPSAEVLQ-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RE7-1", "uniprot_id": "NACC1_HUMAN", "id": "Q96RE7-1", "name": "Nucleus accumbens-associated protein 1", "aln": "MAQTLQMEIPNFGNSILECLNEQRLQGLYCDVSVVVKGHAFKAHRAVLAASSSYFRDLFNNSR----SAVVELPAAVQPQSFQQILSFCYTGRLSMNVGDQFLLMYTAGFLQIQEIMEKGTEFFLKVSSPSCDSQGLHAEEAPSSEPQSPVAQTSG-----------------WPACSTPLPLVSRVKTEQQESD--SVQCMPVAKRLWDSGQKEAG---GGG--NGSRKMAKFSTPDLAANRPHQPPPPQQAPVVAAAQPAVAAGAGQPAGGVAAAGGVVSGPSTSERTSPGTSSAYTSDSPGSYHNEEDEEEDGGEEGMDEQYRQICNMYTMYSMMNVGQTA-EKVEALPEQVAPESRNRIRVRQDLASLPAELINQIGNRCHPKLYDEGDPSEKLELVTGTNVYITRAQLMNCHVSAGTRHKVLLRRLLASFFDRNTLANSCGTGIRSSTNDPRRKPLDSRVLHAVKYYCQNFAPNFKESEMNAIAADMCTNARRVVRKSWMPKVKVLK-AEDDAYTTFISETGKIEPDMMGVEHGFETASHEG-----EAGPSAEALQ-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YZ89-1", "uniprot_id": "A0A8M6YZ89_DANRE", "id": "A0A8M6YZ89-1", "name": "", "aln": "MAQTLQMAIPNFGNNVLECLNEQRLQGLYCDVSVVVKGHTFKAHRAVLAASSSYFRDLFNSSAGSKTPTVVELPPAVQPQSFQQILAFCYTGRLSMNVGDQFLLMYTAGFLQIQQIMEKGTEFFLKVSSPSCDSQGLHTEETPPSEPQSPVTQTAAGAAANGGAGVVATAASRPASCLTPLPLVSRVKTEQPETSPYSVVCTPVAKRLWEGSNREGSGGLGAAGGGGMRKAARFSQEMARGSAIQQQGS------MGGLGMGLGMGTGGHGAGSGSTNGNGTSSATPEGTSPGTLSAYASDSPISYHDDE-EEEEAVDDGTEEQYRQICNMYTMYSMLNVGATAGERVEALPDHS--ETRPRMRGRQDLASLPAELIAQIGNRCHPKLYEEGDPAEKLELVSGTSVYISRAQLMNCHVSAGTRHKVLLRRLLAAFFDRSTLANSCGTGIRSSTNDPSRKPLDSRVLHAVKFYCQNFATSFKESEMNAIAADMCTNARRVVRKSWIPKLKLLM-AEGDAYASFLPDSNKMEADGLSGEPTFETASLEGGASVETGGSSGESLQGVGGDNGTLFQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******* ******.:***********************:********************.* .:*****.***********:**********:******:*********:***********************.**:*.*******:* . .:* ************* * . ** * *:*****:..::*.. *.. .* ** *:** . * . :. .:. :..* :..: .* ***** ***:**** ***::* ***:. ::* :***************:*** *. *:*****:: *:: *:* ************ ***********:****:******:**.***:************************:****.***************** *************:******..*************************:** * * .*.* *::*:.:: *:*.* :. * ***** :* .*.*.* ** ", "identical_positions": 365, "similar_positions": 89, "identity": "63.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010319-31", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920M9-1", "uniprot_id": "SIAH1_RAT", "id": "Q920M9-1", "name": "E3 ubiquitin-protein ligase SIAH1", "aln": "MS------RQTATALPTG-----------TSKCPPSQRVPALTGTTASNN---------------DLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLGSIRNLAMEKVANSVLFPCKYASSGCEITLPHTEKAEHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61092-1", "uniprot_id": "SIA1A_MOUSE", "id": "P61092-1", "name": "E3 ubiquitin-protein ligase SIAH1A", "aln": "MS------RQTATALPTG-----------TSKCPPSQRVPALTGTTASNN---------------DLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLGSIRNLAMEKVANSVLFPCKYASSGCEITLPHTEKAEHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IUQ4-1", "uniprot_id": "SIAH1_HUMAN", "id": "Q8IUQ4-1", "name": "E3 ubiquitin-protein ligase SIAH1", "aln": "MS------RQTATALPTG-----------TSKCPPSQRVPALTGTTASNN---------------DLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLGSIRNLAMEKVANSVLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVG6-1", "uniprot_id": "SIAH1_DANRE", "id": "Q7ZVG6-1", "name": "E3 ubiquitin-protein ligase Siah1", "aln": "MS------RQTATALPTG-----------TSKCPPSQRVPTLSGTTASNS---------------DLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLGSIRNLAMEKVANSVLFPCKYASSGCEVTLPHTDKAEHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLLHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06985-1", "uniprot_id": "SIA1B_MOUSE", "id": "Q06985-1", "name": "E3 ubiquitin-protein ligase SIAH1B", "aln": "MS------RQAATALSTG-----------TSKCPPSQRVPALTDTTASNN---------------DLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLGSIRNLAVEKVANSVLFPCKYSASGCEITLPHTKKAEHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21461-1", "uniprot_id": "SINA_DROME", "id": "P21461-1", "name": "E3 ubiquitin-protein ligase sina", "aln": "MSNKINPKRREPTAAAAGAGATGVATNTSTSTGSSSAGNTSSANTSSSSSSSLSSAGGGDAGMSADLTSLFECPVCFDYVLPPILQCSSGHLVCVSCRSKLTCCPTCRGPLANIRNLAMEKVASNVKFPCKHSGYGCTASLVYTEKTEHEETCECRPYLCPCPGASCKWQGPLDLVMQHLMMSHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYDGHQQFFAIVQLIGSRKEAENFVYRLELNGNRRRLTWEAMPRSIHEGVASAIHNSDCLVFDTSIAQLFADNGNLGINVTISLV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *: .** .:* **. ..* .: :.*::*.. **:*******************.****** .**.************..*****:****..* ****::. ** :* :*.*::*** ** *** ************.** ** **: .***********************************.**************************:**:****.*******:******** *******:*:** ****************:***********: ", "identical_positions": 216, "similar_positions": 44, "identity": "68.79%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010323-11", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GMP8-1", "uniprot_id": "A0A8I6GMP8_RAT", "id": "A0A8I6GMP8-1", "name": "Protein enabled homolog", "aln": "-----------------------------------------MSEQSICQARAAVMVYDDAN----KKWVPAGGSTGFS----------------RVHIYHHTGNNTFRVVGRKIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVLNSQEAAQSKVTATQDSTNLRCIFCVFYLGPTLPR-----------------QNSQLPAQVQNGPSQEEMEIQRRQLQEQQRQKELERERMERERLERERLERERLERERLEQEQL--------------------------ERQRQEREHV--ERLERER--LERLERERQDR---------------------ERERERLEQLEREQVEWERERRMSNAAPSSDSSLYSAPLPEYSSCQPPSAPPPSYAKVISAPVSDAAPDYAVVTALPPTSTP--PTPPLRHSATRFATSLGSAFHPVLPHYATVPRPLNRNSRPSSPVNTPSSQPPAAKSCAWPTSNFSPLPPSPPIMISSPPGKATGPRPVLPVCVSSPVPQMPPSPT-APNGSLDSVTYPVSPPPTSGPAAPPPPPPPPPPPPPPP-PPPPLPPLASLSHCGSQASPPPGTPLASTPSSKPSVLPSPSAAAPASVETPLNPELG------DSSASEPGLQAASQPAETPAPQ-----------GHVLGPPAPPPPPPLPSGPAYAS---ALPPPPGPPPPPP-----LPSAGPPPPPPPPPPLPNQVPPP-PPPPPAPPLPASGIFSGSMSEDNRPLTGLAAAIAGAKLRKVSRVEDGSFPSGGNTVSVNLASSKTDSGRGNGPLPLGGSGLMEEMSALLARRRRIAEK-GSTIETEQKEDRSEDAEPVTSKAASTSTPEPTRKPWERTNTMNGSKSPVISR---------------------PKSTPSSQ--PSANGVQTEGLDYDRLKQDILDEMRKELAKLKEELIDAIRQELSKSNTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03173-1", "uniprot_id": "ENAH_MOUSE", "id": "Q03173-1", "name": "Protein enabled homolog", "aln": "-----------------------------------------MSEQSICQARAAVMVYDDAN----KKWVPAGGSTGFS----------------RVHIYHHTGNNTFRVVGRKIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVLNSQEAAQSKVTATQDSTNLRCIFC----GPTLPR-----------------QNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERMERERLERERLERERLERERLEQEQL--------------------------ERQRQEREHV--ERLERER--LERLERERQ-----------------------ERERERLEQLEREQVEWERERRMSNAAPSSDSSLSSAPLPEYSSCQPPSAPPPSYAKVISAPVSDATPDYAVVTALPPTSTP--PTPPLRHAATRFATSLGSAFHPVLPHYATVPRPLNKNSRPSSPVNTPSSQPPAAKSCAWPTSNFSPLPPSPPIMISSPPGKATGPRPVLPVCVSSPVPQMPPSPT-APNGSLDSVTYPVSPPPTSGPAAPPPPPPPPPPPPPPPLPPPPLPPLASLSHCGSQASPPPGTPLASTPSSKPSVLPSPSAGAPASAETPLNPELG------DSSASEPGLQAASQPAESPTPQ-----------GLVLGPPAPPPPPPLPSGPAYAS---ALPPPPGPPPPPP-----LPSTGPPPPPPPPPPLPNQAPPP-PPPPPAPPLPASGIFSGSTSEDNRPLTGLAAAIAGAKLRKVSRVEDGSFPGGGNTGSVSLASSKADAGRGNGPLPLGGSGLMEEMSALLARRRRIAEK-GSTIETEQKEDRNEDAEPITAKAPSTSTPEPTRKPWERTNTMNGSKSPVISR---------------------PKSTPSSQ--PSANGVQTEGLDYDRLKQDILDEMRKELAKLKEELIDAIRQELSKSNTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N8S7-1", "uniprot_id": "ENAH_HUMAN", "id": "Q8N8S7-1", "name": "Protein enabled homolog", "aln": "-----------------------------------------MSEQSICQARAAVMVYDDAN----KKWVPAGGSTGFS----------------RVHIYHHTGNNTFRVVGRKIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVLNSQET-----------------------GPTLPR-----------------QNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERL--------------------------EQEQLER-----ERQERER--QERLERQER--------------------------LERQERLER-QERLDRERQE------------------------------------------------------------------RQERERLER---------------LERERQERER---------QEQLEREQLEWERE----------RRISS-------------------------------------------------------------------------------------------------------------AAAPASVETPLNSVLG------DSSASEPGLQAASQPAETPSQQ-----------GIVLGPLAPPPPPPLPPGPAQASV--ALPPPPGPPPPPP-----LPSTGPPPPPPPPP-LPNQVPPP-PPPPPAPPLPASGFFLASMSEDNRPLTGLAAAIAGAKLRKVSRMEDTSFPSGGNAIGVNSASSKTDTGRGNGPLPLGGSGLMEEMSALLARRRRIAEK-GSTIETEQKEDKGEDSEPVTSKASSTSTPEPTRKPWERTNTMNGSKSPVISRRDSPRKNQIVFDNRSYDSLHRPKSTPLSQ--PSANGVQTEGLDYDRLKQDILDEMRKELTKLKEELIDAIRQELSKSNTA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B449-1", "uniprot_id": "A0A8M3B449_DANRE", "id": "A0A8M3B449-1", "name": "Protein enabled homolog", "aln": "-------------MQLQSAAQCKVSGFILNERCALSSKMEVHREQSICQARAAVMVYDDAN----KKWVPAGGSTGFS----------------RVHIYHHTGNNAFRVVGRKIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVLNSQDA-----------------------GPPLPR-----------------QTP----QVQNGPSPEELEVQRRQLQELQRQKEKEQERLDRERQERERQEREMLERERTERERQ--------------------------DRERQDRERQERERLERERTEQERLERERQEQELLERERQERELIERERAEREKQEREQQEQLDREQMDWERGRRISNAAFES--TLYTPPPPEYNKTTS------------SSPVSPSTPSYPPPAPLPSTATP--PTPPLRHSASRFATSLGSAFHPVLPHYATVPRRQPAPPTPPPP---APAPPPPSKSVIWTANNFTPLPPSPPVMISSPPGKATGPRPMIAIPAPSPLSQKPPSPISAPNGPPTSLHFHTSSPVSGQPFSSPPTPPPPPPLYSPS------------------PTLPHLAPHVSCPSPQPAVLPSPSTAFPASAEHSVNSGLG------DSCFSAP--EPPTHPADFPSQP-----------DSAHGVPTPPPPPPLPPSSTVTPTTAGPPPPPGPPPPPPPLPPTLTPTGPPPPPGPPPPPSGQAPPPAPPPPPAPPLPSGLFTPSPTTDENKGLSGLAAALAGAKLKKVPRSDEPLAPAAG--PAVSSGGAKPEASRGNGPLPGGG-GLMEEMSALLARRRRIAEK-GSSPEPEQKADDFEAT--VTPKVSACSTPDMPRKPWERTNTMNGSKSPVIGRRDTPWRNQMG-TDKYYDSLNRPRSTPTPTGSISANGVPTEALDYDRLKQDILEEMRKELSKLKEELIDAIREELGKSNSA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8T4F7-4", "uniprot_id": "ENA_DROME", "id": "Q8T4F7-4", "name": "Protein enabled", "aln": "MAMKKLYAKTSFTSKKPSSAANSTPILAYHQQQHQQPGNGICEFQVVAPGHSGELMIRRSQSMHHKMSPPVGGLGSKSEYYSIEELQELDLLDYRHPMYHHYQQQELRQRYHEHEQLVLQLPKATSPKAGPIYEAPQRSQQQQDQMLYVPTAAQRDSSSSAAATSIASSSTLTSSPSPSSSSSLIFSTLRKCVSPSNPSVNPNQPSKTQPSKLGCSMSFSIRTTTATAATAAAANAATATLSTQQQQQQAQQQHKQHLYSNIHHYLIRQQQQKQHYTLQRRHNSVKDKFIGGITTIFAEQSIIGARASVMVYDDNQKKWVPSGSSSGLSKVQIYHHQQNNTFRVVGRKLQDHEVVINCSILKGLKYNQATATFHQWRDSKFVYGLNFSSQNDAENFARAMMHALEVLSGRVANNPGGPPTNGNGYEEDMGYRTMTSEDAAILRQNNSIGGHVTPSAQTPTSQTNQNNIPQSPPTPQGHHRTSSAPPAPQPQQQQQQQQAQQMGQPGSHYGPTGNGPTSNGLPQQVNSQIPPAPQQQPQQQQFQQQQQQQQYQQMVQAGYAPSQQYQQPHYVLSNSNPNLTVHQYPTQQAQQQPPQAPQPPLQNGGMYMVGHGHLPSSASANSVVYASQQQMLPQAHPQAPQAPTMPGPGYGGPPVPPPQQQAENPYGQVPMPPPMNPSQQQQPGQVPLNRMSSQGGPGGPPAPAPPPPPPSFGGAAGGGPPPPAPPQMFNGAPPPPAMGGGPPPAPPAPPAMGGGPPPAPGGPGAPPPPPPPPGLGGAPKKEDPQADLMGSLA-SQLQQIKLKKNKVTTSAPENSGSSTSSGGSGNYGTIGRSSNGMASMMDEMAKTLARRRAQAEKKDPDPEAEVKKRPWEKSNTLPHKLSGGAGSGSAGSGHEGANGNSGGAGSNTTNSGGESPRPMR------KRFGSASEETILKVNGDGLSLALSNGDLDTLKAEIVREMRLEIQKVKNEIIDAIKSEFNRR---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. .::. :: :: * *.** . * * :*** :: :* :: :: : : * . : * :: : :* . ..::.:. *:: : : ..*.*. : .* * .. . ..: :. *::* * *::*: ..:.: .::: ::. :.* : : :.:: . .: : .: :. : .: : : : :.* . * : . * :. . * : . *. *: . * **.*.* *. .: . ****.** . * ***. *.* . *** * * *** *. . ...: :.* .::* ::*::: .: ... . . ... . * . * .:*:**: ***** *** .. *.* * * : :. * .. : . . . * :* .*. .. . . . . .. .: . * * ** :*: *** *: *:*:*:****:.*:.: ", "identical_positions": 99, "similar_positions": 186, "identity": "10.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010328-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIT8-1", "uniprot_id": "Q5XIT8_RAT", "id": "Q5XIT8-1", "name": "Claudin", "aln": "MASMGLQVLGISLAVLGWLGVILSCSLPMWRVTAFIGSNIVTAQTSWEGLWMNCVVQSTGQMQCKMYDSMLALPQDLQAARALMVISIIVGALGMLLSVVGGKCTNCMEDETVKAKVMITAGAVFIVASMLIMVPVSWTAHNVIRDFYNPLVASGQKREMGASLYIGWAASGLLLLGGGLLCCNCPPRRNEKPYSAKYSAARSVPASNYV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35054-1", "uniprot_id": "CLD4_MOUSE", "id": "O35054-1", "name": "Claudin-4", "aln": "MASMGLQVLGISLAVLGWLGIILSCALPMWRVTAFIGSNIVTAQTSWEGLWMNCVVQSTGQMQCKMYDSMLALPQDLQAARALMVISIIVGALGMLLSVVGGKCTNCMEDETVKAKIMITAGAVFIVASMLIMVPVSWTAHNVIRDFYNPMVASGQKREMGASLYVGWAASGLLLLGGGLLCCSCPPRSNDKPYSAKYSAARSVPASNYV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14493-1", "uniprot_id": "CLD4_HUMAN", "id": "O14493-1", "name": "Claudin-4", "aln": "MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIVAGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGLLCCNCPPR-TDKPYSAKYSAARSAAASNYV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P6R7-1", "uniprot_id": "A0A8M1P6R7_DANRE", "id": "A0A8M1P6R7-1", "name": "", "aln": "MVSAGLQMVGIALAVIGWIGVIVVCILPMWQVTAFIGQNIVTAQVTWEGIWMSCVVQSTGQMQCKVYDSMLALSSDLQAARALCIISILVGVVGILLAAAGGKCTTCIKEERAKAKVCVISGAIFIVAGVLCLIPVCWTANNIIRDFYNPMTNSAQKRELGASLFIGWGASALLIIGGSLLCANCPPQ---DQYKATY-TARSGGTKGYV--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Z0S4-1", "uniprot_id": "CLD13_MOUSE", "id": "Q9Z0S4-1", "name": "Claudin-13", "aln": "MVVSKQEAISFSVTSLGWVGAIVSCVLPVWRVT-FPDDETDPDATIWEGLWHICQVRENRWIQCTLYDTRILVAQDIKVSRVFMVICTIGTWLGLLLCVLGDWRINCFMNFTIEENLLKVAGGMFLSVGLLMLVPLSWVTHNIIHGFFNPLLGFSKKVQMGSSLSLAWTSSLLLLLGGILLCVNIPVCRDFPRCIETPSARPSGANNDTLDV", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : :.:::: :**:. :: * **:*:** * ..: . . ***:* * *:.. :**.:**: : :..*::.:*.: :*. : :*:**.. *. .*: : : : :* :*: ..:: ::*:.*.::*:*:.*:**: .:* ::*:** :.* :* **::** *** . * . : * .. : ", "identical_positions": 52, "similar_positions": 86, "identity": "24.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010328-15", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VD75-1", "uniprot_id": "HIP1_MOUSE", "id": "Q8VD75-1", "name": "Huntingtin-interacting protein 1", "aln": "MDRMASSMKQVSNPLPKVLSRRGVGAGMEAAERESFERTQTVSVNKAINTQEVAVKEKHARTCILGTHHEKGAQTFWSVVNRLPLSSNAMLCWKFCHVFHKLLRDGHPNVLKDSLRYKNELSDMSRMWGHLSEGYGQLCSIYLKLLRTRMEYHTKNPRFPGNLQMSDRQLDEAGESDVNNFFQLTVEMFDYLECELNLFQTVFNSLDMSRSVSVTTAGQCRLAPLIQVILDCSHLYDYTVKLLFKLHSCLPADTLQGHRDRFMEQFTKLKDLFQRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHISPVVVIPAEVSSPDSEPVLEKDDLMDMDASQQT-LFDNKFDDVFGSSLSSDPFNFNNQNGVNKDEKDHLIERLYREISGLTGQLDNMKIESQRAMLQLKGRVSELEAELAEQQHLGRQAMDDCEFLRTELDELKRQREDTEKAQRSLTEIERKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQVSVARQAQVDLEREKKELADSFAR--------TQEQQDVLENLKHELATSRQELQVLHSNLETSAQSEAKWLTQIAELEKEQGSLATVAAQREEELSALRDQLESTQIKLAGAQESMCQQVKDQRKTL---------------------LAGIRKAAEREIQEALSQLEEPTLISCAGSTDHLLSKVSSVSSCLEQLEKNGSQYLACPEDISELLHSITLLAHLTGDTIIQGSATSLRAPPEPADSLTEACRQYGRETLAYLSSLEEEGTMENADVTALRNCLSRVKTLGEELLPRGLDIKQEELGDLVDKEMAATSAAIEAATTRIEEILSKSRAGDTGVKLEVNERILGSCTSLMQAIKVLVVASKDLQKEIVESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATIMVDAADLVVQGKGKFEELMVCSREIAASTAQLVAASKVKANKGSLNLTQLQQASRGVNQATAAVVASTISGKSQIEETDSMDFSSMTLTQIKRQEMDSQVRVLELENDLQKERQKLGELRKKHYELAGVAEGWEEGTEASPSTVQEAIPDKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00291-1", "uniprot_id": "HIP1_HUMAN", "id": "O00291-1", "name": "Huntingtin-interacting protein 1", "aln": "MDRMASSMKQVPNPLPKVLSRRGVGAGLEAAERESFERTQTVSINKAINTQEVAVKEKHARTCILGTHHEKGAQTFWSVVNRLPLSSNAVLCWKFCHVFHKLLRDGHPNVLKDSLRYRNELSDMSRMWGHLSEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDVNNFFQLTVEMFDYLECELNLFQTVFNSLDMSRSVSVTAAGQCRLAPLIQVILDCSHLYDYTVKLLFKLHSCLPADTLQGHRDRFMEQFTKLKDLFYRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHISPVVVIPAEASSPDSEPVLEKDDLMDMDASQQN-LFDNKFDDIFGSSFSSDPFNFNSQNGVNKDEKDHLIERLYREISGLKAQLENMKTESQRVVLQLKGHVSELEADLAEQQHLRQQAADDCEFLRAELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQLEVLESLKQELATSQRELQVLQGSLETSAQSEANWAAEFAELEKERDSLVSGAAHREEELSALRKELQDTQLKLASTEESMCQLAKDQRKML---------------------LVGSRKAAEQVIQDALNQLEEPPLISCAGSADHLLSTVTSISSCIEQLEKSWSQYLACPEDISGLLHSITLLAHLTSDAIAHGATTCLRAPPEPADSLTEACKQYGRETLAYLASLEEEGSLENADSTAMRNCLSKIKAIGEELLPRGLDIKQEELGDLVDKEMAATSAAIETATARIEEMLSKSRAGDTGVKLEVNERILGCCTSLMQAIQVLIVASKDLQREIVESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATVMVDAADLVVQGRGKFEELMVCSHEIAASTAQLVAASKVKADKDSPNLAQLQQASRGVNQATAGVVASTISGKSQIEETDNMDFSSMTLTQIKRQEMDSQVRVLELENELQKERQKLGELRKKHYELAGVAEGWEEGTEASPPTLQEVVTEKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R6L2-1", "uniprot_id": "F1R6L2_DANRE", "id": "F1R6L2-1", "name": "Huntingtin-interacting protein 1", "aln": "MDRVKSSMQQVPNPIPKVLSRRAGGANSLEVEKENFERNQAVSINKAINTQEVAVKEKHARTCILGTHHEKGAHTFWLAVNRLPLSSNAVLCWKFCHVFHKLLRDGHPNVIKDSMRHKADLNDMSRMWGHLSEGYGKLCSIYLKLLITKMEFHIKNPRFPGNLQMSNRQLDEAGENDVNNFFQLTVEMFDYLECELNLFLGVFSSLDMSRSVSVTAAGQCRLAPLIQVILDSSHLYDYTVKLLFKLHSCLPADTLQGHRDRFQEQFKKLKSLFYRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHISPVVVIPAEASSPESEHVVETEDLVDTDIPPLTGTGDSKFDDLFGTSAATDPFNFNSQNGMRKDDKDRLIEQLTAELQALKEELESFRLESGRLCQALRGRVNELEAELAEQTHLKQQALGESEFLRAELDDLRRVKEDTEKEQRSLSEIERKAQANEQRYTKLKEKYTELVQSHADLLRKNAEVTRQMTVARAAQDEVENVKKEMQDRLKVAQDSASQQEKAQLEQLQALQAELMSSRTELETLKSTVTSSQQSNEQLGTQLSALVAEKAGLVETVSRKEVELSGLGAELERLQSSLTNERESGVKAAEALQNQLNEKESREQALESELVSLRWASLRAALEEAGKIVQDSLNQLEDPAHISCTSSADYLVSRCQVALDCVERLRSSRDGFVSDNTDVSGLVRAVTQFAHLVGDVIVQGSATSHMVPVEQADALADSVKACGAEALTLLCQLKEQESMGAADCSRLRTALDSVKALGEKLRPRGLELQQGELGDLVEQEMAATSAAVESAAARIEEMLNKSRAVDTGIKMEVNERILASCTDLMQAIRVLVLSSKDLQRDIVESGRGAASMKEFYAKNSRWTEGLISASKAVGWGATMLVDAADQVVQGKGKFEELMVCSHEIAASTAQLVAASKVKAEKGSSNLSRLQQASKGVTQATAGVVASTKSGKSQIEDTETMDFSAMTLTQIKRQEMDAQVLVLELETRLQKERERLGELRKKHYELAGVAEGWGGEEEGTG-----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***: ***:**.**:*******. **. .*:*.***.*:**:*****************************:*** .**********:********************:***:*:: :*.**************:********* *:**:* ************:********.*********************** **.***********:***************.****************************** ***.***.** *******************************************.***:** *:*.:**:* * . . *.****:**:* ::******.***:.**:**:***:* *:..*. :*:.:: ** * *:*:*.****:**** ** :** .:.****:***:*:* :***** ****:*************:******:****.************:*:::** ** ::*. ***: * : : * : *: *: ** :*: **:.*:..: :* **: : :::: * *: .*. .:::* ***.* :*: * .*:. .** : .: :: * * . : * : :*::*.***:*. ***:.*:*:*:* .*:*:*... . ::: *:* *::::* :***..*.* :*::*. .* * **:*::: : * *:*: *..*:*: :: ** : :*..*. :*::**:* ****:::* ******::********:*:*::****:*.**** ***:*:*******..**.*****:**:::*****::*******:** **************************::***** ****:**********:*****************:*.* **::*****:**.****.***** *******:*:.****:************:** *****. *****::****************** *.: ", "identical_positions": 668, "similar_positions": 226, "identity": "63.08%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010328-16", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ALC2-1", "uniprot_id": "A0A8I6ALC2_RAT", "id": "A0A8I6ALC2-1", "name": "Tyrosine-protein kinase BAZ1B", "aln": "MAPLLGRKPFPLVKPLPGE----EPLFTIPHTQEAFRTREEYEARLERYSERIWTCKSTGSSQLTHKEAWEEEQEVAELLKEEFPNWYEKLVLEMVHHNTASLEKLVDSAWLEIMTKYAVGEECDFEVGKEKMLKVKIVKIHPLEKVDEEAAEKKSDGTCDSPSSDKENSSQMAQDHQK-ETVVKEDGGRRESINDRARRSPRKLPTSLKKGERKWAPPKFLPHKYDVKLQSEDKIISNVPADSLIRTERPPNKEILRYFIRHNALRAGTGENAPWVVEDELVKKYSLPSKFSDFLLDPYKYMTLNPSTKRKNTGSPDRKPSKKPK----------------RDNSSLSSPLNPKLWCHVHLEKSLNGPPLKVKNSKNSKSPEEHLEEVMKIMSPN--KLHS-FHIPKKGPSTKKPGKHSDKPLKAKGRGKGILNGQKSTGNSKSPSKCVKTP-KTKMKQMTLLDMAKGTQKMTRTPRSSGGVPRSSGKPHKHLPPAALHLIAYYKENKDKEDKKSALSCVISKTARLLSSEDRARLPEELRALVQKRYELLEHKKRWASMSEEQRKEYLKKKRQELKERLREKAKERREKEMLERLEKQKRYEDQELGGRNLPTFRLVDTPEGLPNTLFGDVALVVEFLSCYSGLLLPDAQYPITAVSLMEALSADKGGFLYLNRVLVILLQTLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRLCLRRCDVQEDSEGSDTDDNKDSTPFEDNEVQDEFLEKLETSEFFELTSEEKLRILTALCHRILMTYSVQDHMETRQQMSAELWKERLAVLKEENDKKRAEKQKRKEMEARNKENGKEENVLGKVD--RKKEIVKIENQVEVEADDMISAVKSRRLLSMQAKRKREIQERETKVRLEREAEEERVRKHKAAAEKAFQEGIAKAKLVLRRTPIGTDRNHNRYWLFSNEVPGLFIEKGWVHNSIDYRFKHHRKDHNNLPDDDYCPRSKKAN--------------LGKNASVNAHLGSALE-AVETTVPKQGQNLWFLCDSQKELDELLNCLHPQGIRESQLKERLEKRYQEITHSIHLARKPNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYMEGTS---EFEARVISLEKLKDFGECVIALQASVIKKFLQGFMAPKQKKRKLQS-EDSTKSEEVDEEKKMVEEAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPPTARRNSRGRNYTEESTSEDSEGDESGDEEEEEEEEEEEEEDYEVAGLRLRPRKTIRG-------KQSVIP----AARPGRPPGKKS-HAARRSRPK----DDTEVDELVLQTKRS-SRRQSLELQKCEEILHKLVKYRFSWPFREPVTRDEAEDYYDVIDHPMDFQTMQNKCSCGNYRSVQEFLTDVKQVFANAELYNCRGSHVLSCMEKTEQCLLALLQKHLPGHPYVRRKRRKFPDRLADDEGDSDSESVGQSRGRRQKK--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z277-1", "uniprot_id": "BAZ1B_MOUSE", "id": "Q9Z277-1", "name": "Tyrosine-protein kinase BAZ1B", "aln": "MAPLLGRKPFPLVKPLPGE----EPLFTIPHTQEAFRTREEYEARLERYSERIWTCKSTGSSQLTHKEAWEEEQEVAELLKEEFPNWYEKLVLEMVHHNTASLEKLVDSAWLEIMTKYAVGEECDFEVGKEKMLKVKIVKIHPLEKVDEEAVEKKSDGACDSPSSDKENSSQMAQDLQKKETVVKEDEGRRESINDRARRSPRKLPTSLKKGERKWAPPKFLPHKYDVKLQNEDKIISNVPADSLIRTERPPNKEILRYFIRHNALRAGTGENAPWVVEDELVKKYSLPSKFSDFLLDPYKYMTLNPSTKRRNTGSPDRKPSKKPK----------------RDSSSLSSPLNPKLWCHVHLEKSLNGPPLKVKNSKNSKSPEEHLEGVMKIMSPNNNKLHS-FHIPKKGPAAKKPGKHSDKPLKAKGRGKGILNGQKSTGNSKSPSKCVKTP-KTKMKQMTLLDMAKGTQKMTRTPRSSGGVPRSSGKPHKHLPPAALHLIAYYKENKDKEDKKSALSCVISKTARLLSNEDRARLPEELRALVQKRYELLEHKKRWASMSEEQRKEYLKKKRQELKERLREKAKERREREMLERLEKQKRFEDQELGGRNLPAFRLVDTPEGLPNTLFGDVALVVEFLSCYSGLLLPDAQYPITAVSLMEALSADKGGFLYLNRVLVILLQTLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRLCLRRCDVQEDSEGSETDDNKDSTPFEDNEVQDEFLEKLETSEFFELTSEEKLRILTALCHRILMTYSVQDHMETRQQVSAELWKERLAVLKEENDKKRAEKQKRKEMEARNKENGKEENVLGKVD--RKKEIVKIEQQVEVEADDMISAVKSRRLLSMQAKRKREIQERETKVRLEREAEEERMRKHKAAAEKAFQEGIAKAKLVLRRTPIGTDRNHNRYWLFSNEVPGLFIEKGWVHNSIDYRFKHHRKDHSNLPDDDYCPRSKKAN--------------LGKNASVNAHHGPALE-AVETTVPKQGQNLWFLCDSQKELDELLSCLHPQGIRESQLKERLEKRYQEITHSIYLARKPNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYMEGTS---EFEARVISLEKLKDFGECVIALQASVIKKFLQGFMAPKQKKRKLQS-EDSTKSEEVDEEKKMVEEAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPPTARRNSRGRNYTEESTSEGSEGDESGEEEEEEEEEEEEEEDYEVAGLRLRPRKTIRG-------KQSVIP----AARPGRPPGKKS-HPARRSRPK----DDPEVDDLVLQTKRI-SRRQSLELQKCEDILHKLVKYRFSWPFREPVTRDEAEDYYDVIEHPMDFQTIQNKCSCGNYRSVQEFLTDMKQVFANAELYNCRGSHVLSCMEKTEQCLLALLQKHLPGHPYVRRKRRKFPDRLADDEGDSDSESVGQSRGRRQKK--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UIG0-1", "uniprot_id": "BAZ1B_HUMAN", "id": "Q9UIG0-1", "name": "Tyrosine-protein kinase BAZ1B", "aln": "MAPLLGRKPFPLVKPLPGE----EPLFTIPHTQEAFRTREEYEARLERYSERIWTCKSTGSSQLTHKEAWEEEQEVAELLKEEFPAWYEKLVLEMVHHNTASLEKLVDTAWLEIMTKYAVGEECDFEVGKEKMLKVKIVKIHPLEKVDEEATEKKSDGACDSPSSDKENSSQIAQDHQKKETVVKEDEGRRESINDRARRSPRKLPTSLKKGERKWAPPKFLPHKYDVKLQNEDKIISNVPADSLIRTERPPNKEIVRYFIRHNALRAGTGENAPWVVEDELVKKYSLPSKFSDFLLDPYKYMTLNPSTKRKNTGSPDRKPSKKSK----------------TDNSSLSSPLNPKLWCHVHLKKSLSGSPLKVKNSKNSKSPEEHLEEMMKMMSPN--KLHTNFHIPKKGPPAKKPGKHSDKPLKAKGRSKGILNGQKSTGNSKSPKKGLKTP-KTKMKQMTLLDMAKGTQKMTRAPRNSGGTPRTSSKPHKHLPPAALHLIAYYKENKDREDKRSALSCVISKTARLLSSEDRARLPEELRSLVQKRYELLEHKKRWASMSEEQRKEYLKKKREELKKKLKEKAKERREKEMLERLEKQKRYEDQELTGKNLPAFRLVDTPEGLPNTLFGDVAMVVEFLSCYSGLLLPDAQYPITAVSLMEALSADKGGFLYLNRVLVILLQTLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRLCLRRSDVQEESEGSDTDDNKDSAAFEDNEVQDEFLEKLETSEFFELTSEEKLQILTALCHRILMTYSVQDHMETRQQMSAELWKERLAVLKEENDKKRAEKQKRKEMEAKNKENGKVENGLGKTD--RKKEIVKFEPQVDTEAEDMISAVKSRRLLAIQAKKEREIQEREMKVKLERQAEEERIRKHKAAAEKAFQEGIAKAKLVMRRTPIGTDRNHNRYWLFSDEVPGLFIEKGWVHDSIDYRFNHHCKDHTVSGDEDYCPRSKKAN--------------LGKNASMNTQHGTATEVAVETTTPKQGQNLWFLCDSQKELDELLNCLHPQGIRESQLKERLEKRYQDIIHSIHLARKPNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYVEETS---EFEARVISLEKLKDFGECVIALQASVIKKFLQGFMAPKQKRRKLQS-EDSAKTEEVDEEKKMVEEAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPATARRNSRGRNYTEESASEDSEDDES-DEEEEEEEEEEEEEDYEVAGLRLRPRKTIRG-------KHSVIPP---AARSGRRPGKKP-HSTRRSQPKAPPVDDAEVDELVLQTKRS-SRRQSLELQKCEEILHKIVKYRFSWPFREPVTRDEAEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNAEVYNCRGSHVLSCMVKTEQCLVALLHKHLPGHPYVRRKRKKFPDRLAEDEGDSEPEAVGQSRGRRQKK--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BIL7-1", "uniprot_id": "BAZ1B_DANRE", "id": "A2BIL7-1", "name": "Tyrosine-protein kinase BAZ1B", "aln": "MAPLLGRKPYPLVKPLSEPPGPGEEVYTIEHTKEAFRNKEEYEARLRRYGERIWTCKSTGSSQLTHKEAWEEEQEVTELLQEEYPVWFEKPVLEIVHHNTVPLDKLVDQVWVEILTKYAVGEKCDLMVGNDKTLSVEVVKIHPLENPPEENAEKKMEGACDSPSSDKENAS---QENLKKEPQSKEEESRRESLSDRARRSPRKLPTTMKEEKKKWVMPKFLPHKYDVKLVNEDKVISDVPADNLFRTERPPNKEIMRYFIRHYALRLGSGESAPWVVEDELVKKFSLPSKFSDFLLDPHKFLAENPSTKRKSLSSPEGKPRKRLKNVETGTGGEGAKGDKKKNKDSQNIPLSPTIWSHMQVKK-VNGSPLKMKNSGTSKKSDE----------------ENVLGTPK---SSKKQGDKKSSDPKRR-RKSGLNKTPNSQRLSKKEDKSLGGAKKPRMKQMTLLDLAKSPAAAGSPKKQRRSSTTGSAKLGKPFPPMALHLLRFYKENKGKEDKKTTLSSLLSKAAKALSPEDRSRLPEELKELVQKRWELLEQKRRWALMSEEEKQSVLKQKRQEVKQKLREKAKERREKEMQVRREMSRRYEDQELEGKNLPAFRLFDMPEGLPNTIFGDVAMVVEFLHCYSGLLMPDDQYPITSIALLEALAGEKAGFLYLNRVLVVLLQTLLQDELAEGYSELDMPLSEIPLTMHSVSELVRLCLRPSDAHEEESARGSDDWQSGADFDD-MVSSEFLEKLETAEVFELDPQEKVSLLLALCHRILMTYSVEDHVEAVHQKSAEMWKERVATLKEANDRKRAEKQKRKEQMETKTDGDVLIKAEKKKESTVKKETPKVLPKEEPEPEDMISTVKSRRLMSIQAKKEKEEQERLNKVRMEKEAEEERIRRQKAATEKAFQDAVTKAKLVLRRTPLGTDRNHNRYWLFSDVVPGLYIEKGWVHESIDYSFTLPPEEEPVLTEEEEEEEEVKKEEETEDGEKEDEGSIISASNDISQQGAPSHESSIETTVPKQGQNLWFVCDTPKDFDELLESLHPQGVRESELKIRLQINYQEILHSIHLTKKGNPGLKTCDGHQELLKFLRSDIIEVASRLQKGGLGYLEDTSEFEEFEERVKTLEKLPEFGECVIALQESVIKKFLQGFMAPKQKKKKKTGGEESTTAEEVDDQKKLAEEARVATAVEKWKTAVREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRRKGEDDKLILCDECNKAFHLFCLRPALYRIPAGEWLCPACQPTIARRSSRGRNYKEDSE----EEEDSEEEDEEESEEEDSEEEHRNTGHSLRSRKKVKTSSKSKMQKKPAKPASRSASKTDTNPSKTSPKSSAKPKSRAAPSSPVDIDELVRQSSKPPSRKKDVELQKCEEILQKIMKFRHSWPFREPVSAEEAEDYQDVITSPMDLTTMQGKFKSSEYHSASDFIEDMKLIFSNAEEYNQPSSNVLTCMSRTEEAFVELLQKSLPGVSYLRRRTRKRAATPSDNSDDDDDDEEEDERSKKQKNGKQGKKASSKRKVEHSRTEKYQTKQK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********:******. * ::** **:****.:*******.**.**************************:***:**:* *:** ***:*****..*:**** .*:**:*******:**: **::* *.*::*******: ** .*** :*:**********:* *: * *. **: .****:.************::*: ::**. ************ .***:**:****.*:**********:****** *** *:**.************:*************:*::: ******:. .**: ** *: * :..* . **.*.:*.*::::* :.*.***:*** .**..:* .. : ** .:** *.:... * : * .*: : :* **. .* : . *.:********:**.. . :. . . *.* * :** ****: :*****.:***:::**.::**:*: ** ***:******: *****:****:*:*** ****:::. **:**:*:*::*:********:** * * .:*:***** *:***:***.* *******:*****:***** ******:** *****:::*:***:.:*.**********:*********:**.*.**.* *******:************ .*.:*:... :** :..: *:* *..********:*.*** .:**: :* ************:**:*: :* ***:****:*.*** **:********** :.:.. : * : *** *. : : *.:****:******:::***:::* *** **::*::*****:*::***:*****:.::*****:****:*************: ****:*******:**** *. ::. ::: .. * : :. . .:. : ..: * ::***.*********:**: *::****..*****:***:** **: .**:* ***:*::* * ***:***:****:*****:****:*********:* ** *** ** :**** :********* ****************::* . *:*:.:****::**:.***:**:*:******:***********************************:***************************.:* *** ******. ***.******.*:* * ::* :*:***.***:.**::. :* **.**.:: *:.. * *::.. *.*.. :.: :.:.: . ::*:** *:.: **::.:******:**:*::*:*.********: :***** *** ***: *:*.* ....*:*..:*: *:* :*:*** ** .*:**:** :**:.:: **:* *** .*:**: :* . :::..*.: : :.*.::**: ", "identical_positions": 872, "similar_positions": 391, "identity": "55.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010328-17", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1H245-1", "uniprot_id": "B1H245_RAT", "id": "B1H245-1", "name": "", "aln": "MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKSKSNNTAAREPNGFPSDASAN--SSLLLEFQDENSNQSSVSDVYQ--LKVDSSTNSSPSPQQSESLSPAHTSDFRTDDSQPPTLGQEILE---EPSLPASEVADEPPTLTKEEPVPIETQTTEEEEDSGAPPLKRFCVDQPVVPQTTSES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q921K9-1", "uniprot_id": "BCL7B_MOUSE", "id": "Q921K9-1", "name": "B-cell CLL/lymphoma 7 protein family member B", "aln": "MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKSKSNNTAAREPNGFPSDASAN--SSLLLEFQDENSNQSSVSDVYQ--LKVDSSTNSSPSPQQSESLSPAHTSDFRTDDSQPPTLGQEILE---EPSLPASEVADEPPTLTKEEPVPVETQTTEEEEDSGAPPLKRFCVDQPVVPQTTSES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQE9-1", "uniprot_id": "BCL7B_HUMAN", "id": "Q9BQE9-1", "name": "B-cell CLL/lymphoma 7 protein family member B", "aln": "MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKSKSNSSAAREPNGFPSDASAN--SSLLLEFQDENSNQSSVSDVYQ--LKVDSSTNSSPSPQQSESLSPAHTSDFRTDDSQPPTLGQEILE---EPSLPSSEVADEPPTLTKEEPVPLETQVVEEEEDSGAPPLKRFCVDQPTVPQTASES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BIL8-1", "uniprot_id": "BC7BB_DANRE", "id": "A2BIL8-1", "name": "B-cell CLL/lymphoma 7 protein family member B-B", "aln": "MSGRSVRAETRSRAKDDIKKVMAAIERVRRWEKKWVTVGDTSLRIFKWVPVTETKQIYKPKGAGPAVRELKGFPTDVVLENARSVLLDFQDDNSNQSFLSDAYQSNTKVDSSSNSSPQ-HVSEAVSPSHPPYYRTEDSQPPTLGQESMEAEREASTTSSEVTDEPPTLIKEDVLSLSTQ--EEEEAIGAPPLKRVCTEH---NSTVS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O76857-1", "uniprot_id": "O76857_DROME", "id": "O76857-1", "name": "", "aln": "-MSRSVRAETRSRAKDDIKRVMQAVDKVRHWEKKWVTISDTTMKIYKWVPIASASEKKAKLESSPGSAAVRRPPPGSGVT---------------------------PVGGSKSDKENSQKGTPTPPQITPSYQGLTAEDSNTCFSVVS--------DSQGADFVSSMPFSE---------DSNSQGSDGPVKRLKTSD----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .****************:** *:::**:*******:.**:::*:****::.:.: ... . *.. *..*.... . : . . .* .. :: :: .. . :. *: :* .:: .: :.:. . *:**. ... ", "identical_positions": 44, "similar_positions": 63, "identity": "21.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010328-18", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KA15-1", "uniprot_id": "A0A0G2KA15_RAT", "id": "A0A0G2KA15-1", "name": "General transcription factor II-I repeat domain-containing protein 1", "aln": "MALLGKH-CDIPTNGCGSERWNSTFARKDELINSLVSALDSMCSALSKLNTEVACVAVHNESVFVMGTEKGRVFLNTRKELQSDFLRFCRGPLWNDPEAGHPK---------KVQRCEGGGRSIPRSSLEQCSDVYLLQKMVEEVFDVLYSEAMGRATVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLRRPPDDGGQDTKALVEMNGISLLPKGSRDCGLHGQASKVSPQDLTPTATPSSMANFLYSTSMPNHTIRELKQEVPTCPLTPSDLGLGWP-VPEPHVPSTQDFSDCCGQ-APAGPAGPLIQN---VHASKRILFSIVHDKSEKWDPFIKEMEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIFTGN-KFTKDPMKLEPASP----PEDTATEVCRDSMLDLAGTAWSDMSSVS--EDCGPGTSGEIGMLRPIKIEPEELDIIQVTVSDPSPTSEEMTDSLPGHLPSEDSGYGMEMPADKGPSEEPWQEERPAEESPGDVIRPLRKQVEMLFNTKYAKAIGTSEPVKVPYSKFLMHPEELFVLGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTDGVKEPVMDTQ---------------ERDSWDPLVDETP--KRQGLQENYNTRLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILSVADKIKFTVTRPFQGLIPKP---------------------------DEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTYDIHRLEKILKARDHVRMVIINQLQPFTEVCNDP-------------------------------------------------------------------------------------------------------KVPAKDN-IPKRKRKRVSEGNSVSSSSSSSSSSSSNPESVASTNQISLVQ------------WPVYMVDY-------SGLNVQLPGPLDY-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JI57-1", "uniprot_id": "GT2D1_MOUSE", "id": "Q9JI57-1", "name": "General transcription factor II-I repeat domain-containing protein 1", "aln": "MALLGKH-CDIPTNGCGSERWNSTFARKDELINSLVSALDSMCSALSKLNTEVACVAVHNESVFVMGTEKGRVFLNTRKELQSDFLRFCRGPLWNDPEAGHPK---------KVQRCEGGGRSLPRSSLEQCSDVYLLQKMVEEVFDVLYSEAMGRATVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLRRPPDDGGQDTKALVEMNGISLLPKGSRDCGLHGQASKVAPQDLTPTATPSSMANFLYSTSMPNHTIRELKQEVPTCPLTPSDLGMGWP-VPEPHVPSTQDFSDCCGQ-TPAGPAGPLIQN---VHASKRILFSIVHDKSEKWDPFIKEMEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIFTGN-KFTKDPMKLEPASP----PEDTSTEVCRDSMLDLAGTAWSDMSSVS--EDCGPGTSGEIAMLRPIKIEPEELDIIQVTVSDPSPTSEEMTDSLPGHLPSEDSGYGMEMPADKGPSEEPWSEERPAEESPGDVIRPLRKQVEMLFNTKYAKAIGTSEPVKVPYSKFLMHPEELFVLGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTDGVKEPVLDTQ---------------ERDSWDRLVDETP--KRQGLQENYNTRLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILSVADKIKFTVTRPFQGLIPKPETKILTTGHEAGKTTRPRRLQQDTWQPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEVCNDPKVPEEDDSNKLGKKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFGDVCNNAKVPAKDN-IPKRKRKRVSEGNSVSSSSSSSSSSS-NPESVASTNQISLVVKSRGSELHPNSVWPLPLPRAGPSTAPGTGRHWALRGTQPTTEGQAHPLVLPTR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHL9-1", "uniprot_id": "GT2D1_HUMAN", "id": "Q9UHL9-1", "name": "General transcription factor II-I repeat domain-containing protein 1", "aln": "MALLGKR-CDVPTNGCGPDRWNSAFTRKDEIITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVGTEKGRMFLNARKELQSDFLRFCRGPPWKDPEAEHPK---------KVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGVSLIPKGSRDCGLHGQAPKVPPQDLPPTATSSSMASFLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRP-MPEPKATGAQDFSDCCGQ-KPTGPGGPLIQN---VHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIFTGN-KFTKDTTKLEPASP----PEDTSAEVSRATVLDLAGNARSDKGSMS--EDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPVEDSHGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIMDSQGTASSLGFSPPALPPERDSGDPLVDESL--KRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRPFQGLIPKP---------------------------DEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDA-------------------------------------------------------------------------------------------------------KVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQISLVQ------------WPMYMVDY-------AGLNVQLPGPLNY-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PLI6-1", "uniprot_id": "A0A8M9PLI6_DANRE", "id": "A0A8M9PLI6-1", "name": "", "aln": "MAQIRKLGCDGMRTNSRPELKVPQVSARQEILTSLVSALDSVCSAMSKLNAEVACVTVHEDSVIAVGTEKGRIFLNSRKEIQTDFHKFCKVSCLQALNSMNSHSKVPEVDCSRTGKDSSGQQGRQRALTDTHSNIFVLRKMVEEVFSVLYSEAVGKSSLVPVPYDWILKDPSSVVVYGLPDGVTLRKPSEYDTKTLMKILEQSNRIRFIVKRTPEEPSRDAKSCPEVNHHSSTSKSAS------NHTSVKPSVQEVSASNSMLSSFLYGMPMSSQPHPDSKLDLKPTSLHS--IGKERPGMWTPAEEKAVQAKECADNGERIGLAADLTQSPPSIHVSKRLLFSIVHEKSEKWDSFIRETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIIGIPDKIPFKRPCTYGVPKLKRILEERHAVRFVVRRMFDERIFTAAGKVAKEEGKQDGPASEDGFPEGLRIPSSSLELVSNTHSSRSTSSCVSPLAECEAGPSGDCLPLKKIKTEPPDGEIIQVTVPESSASTEESSEPQAERVTPDLCRPKEPVAEDLTPKSTPQGLKRAVEEDIGEMILQLRKQVESLFSCKYSEALGLPEPAKVPYSKFQMYPDDLYVTGLPEGMTFRRPNCFGAAKLRKILSASSQITFVITRPELLTEPVKNESVSKTTSES----------AETDSKDQSDDPGPASKRPGFSDSLEAKLSRIDLANTLREQVQDLFNRKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKISFSITRPFQGLIPKPAPRRITILKKG-----------YTPISEEDEVNRMGEKVILREQVKELFNKKYGEALGLDRSVIVPYKLIRANPGSLEVCGLPDDIPFRNPNTYDIVRLEKVLQAQDEITFNIKTPLQPFTELCTQS------------------------------------------------------------------------------------------------------CNKEGKEVSTNRRKRKRVLE--------SSQTSMPTAGDSALSTNQIPVMQ------------WPMYMVDY-------SGVNVQVPGKVKY-------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : * ** ... .: . .: ::*::.********:***:****:*****:**::*.:.:******:***:***:*:** :**: . : :: :.: :. : ..* :. *: : *::::*:*******.******:*::::**:**: :*::*. :.* ***:*:::*:*:***.*:** ***:*:**** ::*. :: .:*:*: *:* * .*.: : ..* *. :*: * ::.***. .:..:. : * : . .* . :* * : * : : .:*..: * .. * *. :*.***:******:******.**:* ********************************************:***************************:::*:::*********. *.:*: * : .:. **. . ::. : .: * ..:* :* .*.**: *: ** ** : :******.:.*.::** ::. . ::..: . : * .. . :*..*:. *::* ****** **. :*::*:* .**.******* *:*::*:* *****:::******* *******.**..* ***.******: **: :.. * ** * * ** *:.:. :::*****:*************:****************************************************:*****.*::*********** :**:.**:***************:********:*.*:******* .*.::** **************** ****:*:*::.: : * . ****:*:*.:. : .*: :****** * **.:* . :*. *:***.:: **: : :* : : * ", "identical_positions": 484, "similar_positions": 266, "identity": "42.27%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010328-19", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q15056-1", "uniprot_id": "IF4H_HUMAN", "id": "Q15056-1", "name": "Eukaryotic translation initiation factor 4H", "aln": "MADFDTYDDR--AYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRKQDKGG--FGFRKGGPDDRGMGSSRESRGG-WDSRDDFNS---------GFR-DDFLGGR--GGSRPGDRRTGPPMG-------SRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WUK2-1", "uniprot_id": "IF4H_MOUSE", "id": "Q9WUK2-1", "name": "Eukaryotic translation initiation factor 4H", "aln": "MADFDTYDDR--AYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRKQDKGG--FGFRKGGPDDRGMGGSRESRGG-WDSRDDFNS---------GYR-DDFLGGR--GGSRPGDRRAGPPMG-------SRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IG09-1", "uniprot_id": "A0A0R4IG09_DANRE", "id": "A0A0R4IG09-1", "name": "Eukaryotic translation initiation factor 4H", "aln": "MADYDNYDDRDRAYGSFGGGRGPRGGGGPSGPRKQKELPTEPPYTAYVGNLPFNTVQGDIDAIFRDLSVRSVRLVRDKETDKFKGFCYVEFDDLESLKEALTYDGALLGDRSLRVDIAEGRRQERGGGGFGFRK---DDRGRGGSRGARGGGRDSREDFDQSGGGAAGEMGFRDDDFMGGRSRGGGRPGDRRGGAGGGGGGGGGMGRFRDGPP-RGGQTDFREPSDEERAQRPRLQLKPRTVAGPLNQVANPNSAIFGGAKPREEN------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*.**** **.*******.**..* *.*.******************************:***:*********:*************:::**************************:*::** ***** **** *.** :*** ***:**:. *:* ***:*** **.****** *. * .******* **.: *****::***************** ****************:**** ", "identical_positions": 195, "similar_positions": 32, "identity": "71.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010328-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIT8-1", "uniprot_id": "Q5XIT8_RAT", "id": "Q5XIT8-1", "name": "Claudin", "aln": "MASMGLQVLGISLAVLGWLGVILSCSLPMWRVTAFIGSNIVTAQTSWEGLWMNCVVQSTGQMQCKMYDSMLALPQDLQAARALMVISIIVGALGMLLSVVGGKCTNCMEDETVKAKVMITAGAVFIVASMLIMVPVSWTAHNVIRDFYNPLVASGQKREMGASLYIGWAASGLLLLGGGLLCCNCPPRRNEKPYSAKYSAARSVPASNYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35054-1", "uniprot_id": "CLD4_MOUSE", "id": "O35054-1", "name": "Claudin-4", "aln": "MASMGLQVLGISLAVLGWLGIILSCALPMWRVTAFIGSNIVTAQTSWEGLWMNCVVQSTGQMQCKMYDSMLALPQDLQAARALMVISIIVGALGMLLSVVGGKCTNCMEDETVKAKIMITAGAVFIVASMLIMVPVSWTAHNVIRDFYNPMVASGQKREMGASLYVGWAASGLLLLGGGLLCCSCPPRSNDKPYSAKYSAARSVPASNYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14493-1", "uniprot_id": "CLD4_HUMAN", "id": "O14493-1", "name": "Claudin-4", "aln": "MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIVAGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGLLCCNCPPR-TDKPYSAKYSAARSAAASNYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9YH91-1", "uniprot_id": "CLDY_DANRE", "id": "Q9YH91-1", "name": "Claudin-like protein ZF-A89", "aln": "MASVGLQLLATVLAIIGWLGEIVICALPMWKVTAFIGNNIVTAQIFWEGLWMNCVQQSTGQMQCKVYDSMLALPQDLQAARALVVISIIVTFMGVFLTIAGGKCTNCIEDQDAKAKVVVAAGVFFLVGGILCLIPVCWSANSVIKDFYNPTLSDAQKRELGASLFIGWCASGLLLLGGALLCCQCPKN-EGRAYSVKYSAPRSAPG-AYV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:***::. **::***. :: *:****:******.****:* ********* *********:***:*************::***** :*::*::.*******:**: .*** ::.**..*::..:: ::**.*:*:.:*:***** ::..****:****::**.*********.****.** . :.**.****.**... **", "identical_positions": 128, "similar_positions": 63, "identity": "60.95%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010328-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIT8-1", "uniprot_id": "Q5XIT8_RAT", "id": "Q5XIT8-1", "name": "Claudin", "aln": "MASMGLQVLGISLAVLGWLGVILSCSLPMWRVTAFIGSNIVTAQTSWEGLWMNCVVQSTGQMQCKMYDSMLALPQDLQAARALMVISIIVGALGMLLSVVGGKCTNCMEDETVKAKVMITAGAVFIVASMLIMVPVSWTAHNVIRDFYNPLVASGQKREMGASLYIGWAASGLLLLGGGLLCCNCPPRRNEKPYSAKYSAARSVPASNYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35054-1", "uniprot_id": "CLD4_MOUSE", "id": "O35054-1", "name": "Claudin-4", "aln": "MASMGLQVLGISLAVLGWLGIILSCALPMWRVTAFIGSNIVTAQTSWEGLWMNCVVQSTGQMQCKMYDSMLALPQDLQAARALMVISIIVGALGMLLSVVGGKCTNCMEDETVKAKIMITAGAVFIVASMLIMVPVSWTAHNVIRDFYNPMVASGQKREMGASLYVGWAASGLLLLGGGLLCCSCPPRSNDKPYSAKYSAARSVPASNYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14493-1", "uniprot_id": "CLD4_HUMAN", "id": "O14493-1", "name": "Claudin-4", "aln": "MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIVAGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGLLCCNCPPR-TDKPYSAKYSAARSAAASNYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9YH90-1", "uniprot_id": "CLDZ_DANRE", "id": "Q9YH90-1", "name": "Claudin-like protein ZF-A9", "aln": "-MSTGLQLLGTTLGTLGWLGIIISCAIPLWRVTAFIGNNIVTAQTMWEGLWMSCVVQSTGQMQCKVYDSMLALAQDLQASRAILVISAIVGLIAMFASFAGGKCTNCLADNSAKALVATTGGVAFIIAGILGLVPPSWTANTIIRDFYNPLVAEAQKREFGAAIFICWGAAVLLVIGGGLLCSSYPKGRTSSRGRYTPASQNGRERSEYV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ***::* :*..****.:::.*::*:********.****:** ******.************:***:***.*****:**:::** **. :.:: *..*******: *::.** ..*..*::*.:: :** ****:.:*:*****:**..****:**:::: *.*: **::******.. * ... . :: .. *:**", "identical_positions": 109, "similar_positions": 71, "identity": "51.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010403-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WTQ9-1", "uniprot_id": "Q9WTQ9_RAT", "id": "Q9WTQ9-1", "name": "Cone-rod homeobox protein", "aln": "------------------MMTYMNPGPHYSVNALALSG---------PSVDLMHQAVPYSS------------APRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGVQAKARPAKRKAGTSPRPSTDVCTDPLGISDSYSPSLPG-----------------------------------PSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGSSLTSAPYAMTYA---------------PASAFCSSPSAYASPSSYFSGLD--PYLSPMVPQLG--------------------------------------------------------------------------------------------GPALSPLSG--------PSVGPSLAQSPTSLSGQSYST----YSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54751-1", "uniprot_id": "CRX_MOUSE", "id": "O54751-1", "name": "Cone-rod homeobox protein", "aln": "------------------MMAYMNPGPHYSVNALALSG---------PNVDLMHQAVPYSS------------APRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGAQTKARPAKRKAGTSPRPSTDVCTDPLGISDSYSPSLPG-----------------------------------PSGSPTTAVATVSIWSPASEAPLPEAQRAGLVASGPSLTSAPYAMTYA---------------PASAFCSSPSAYASPSSYFSGLD--PYLSPMVPQLG--------------------------------------------------------------------------------------------GPALSPLSG--------PSVGPSLAQSPTSLSGQSYST----YSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL-----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43186-1", "uniprot_id": "CRX_HUMAN", "id": "O43186-1", "name": "Cone-rod homeobox protein", "aln": "------------------MMAYMNPGPHYSVNALALSG---------PSVDLMHQAVPYPS------------APRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPG-----------------------------------PSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGPSLTSAPYAMTYA---------------PASAFCSSPSAYGSPSSYFSGLD--PYLSPMVPQLG--------------------------------------------------------------------------------------------GPALSPLSG--------PSVGPSLAQSPTSLSGQSYGA----YSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JIZ3-1", "uniprot_id": "Q8JIZ3_DANRE", "id": "Q8JIZ3-1", "name": "", "aln": "------------------MMSYIKQ-PHYAVNGLTLSA---------SGMDLLHTAVGYPA------------TPRKQRRERTTFTRTQLDILEALFTKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ------QQQTSG-QPKPRPPKKKS--SPPP--DLTSDPGTSSSVVAAPTPT-----------------------------------VPPSVSAGTAPVSVWSPTSLSPLPDPLCG--SGTPCVQRPAPYPMSYG---------------QPSSYSQG---YGS-SPYFSGLDCSPYLSPMTTQLSAS------------------------------------------------------------------------------------------GGALSPLTV--------PSMGGSLSQSP-SLSSQGYSTASLGFSSVDCLDYKDQQ-AWKLNFSTVDCLDHK------FQVL-----------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22810-1", "uniprot_id": "HMOC_DROME", "id": "P22810-1", "name": "Homeotic protein ocelliless", "aln": "----MAAGFLKSGDLGPHPHSYGGPHPHHSVPHGPLPPGMPMPSLGPFGLPHGLEAVGFSQG-------MWGVNTRKQRRERTTFTRAQLDVLEALFGKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQLQQQQQSNSLSSSKNASGGGSGNSCSSSSANSRSNSNNNGSSSNNNTQSSGGNNSNKSSQKQGNSQSSQQGGGSSGGNNSNNNSAAAAASAAAAVAAAQSIKTHHSSFLSAAAAAASGGTNQSANNNSNNNNQGNSTPNSSSSGGGGGSQAGGHLSAAAAAAALNVTAAHQNSSPLLPTPATSVSPVSIVCKKEHLSGGYGSSVGGGGGGGGASSGGLNLGVGVGVGVGVGVGVSQDLLRSPYDQLKDAGGDIGAGVHHHHSIYGSAAGSNPRLLQPGGNITPMDSSSSITTPSPPITPMSPQSAAAAAHAAQSAQSAHHSAAHSAAYMSNHDSYNFWHNQYQQYPNNYAQAPSYYSQMEYFSNQNQVNYNMGHSGYTASNFGLSPSPSFTGTVSAQAFSQNSLDYMSPQDKYANMV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A6NJG6-1", "uniprot_id": "ARGFX_HUMAN", "id": "A6NJG6-1", "name": "Arginine-fifty homeobox", "aln": "MRNRMAPENPQPDPFINRNYSNMKVIPPQDPASPSFTLLSKLECSGTVSAYCSLNLPGSTDPPTSASRVAATTAIRRRHKERTSFTHQQYEELEALFSQTMFPDRNLQEKLALRLDLPESTVKVWFRNRRFKLKKQ-----QQQQSAKQRNQILPSKKNVPTSPRTSPSPYAFSPVISDFYSSLPSQ-----------------------------------PLDPSNWAWNSTFTESSTSDFQMQDTQWERLVASVPALYSDAYDIFQI-----------------IELYNLPDENEISSSSFHCLY--QYLSPTKYQVGGQ------------------------------------------------------------------------------------------GSSLSIFAG--------PAVGLSPAQTWPNMTSQAFEA----YSLTDSLEFQKTSNMVDLGFL-----------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NFQ7-1", "uniprot_id": "DPRX_HUMAN", "id": "A6NFQ7-1", "name": "Divergent paired-related homeobox", "aln": "-------------------------------------------------MPGSEDLRKGKD-------------QMHSHRKRTMFTKKQLEDLNILFNENPYPNPSLQKEMASKIDIHPTVLQVWFKNHRAKLKKA-------------KCKHIHQKQETPQPPIPEGGVSTSVGLRNADTLPRLPN-----------------------------------------AAHPIGLVYTGHRVPSFQLILYPNLKVPANDFIGHRIV-HFG---------------------------CCRDPNIYCLY--PILESQVCAPS------------------------------------------------------------------------------------------------------------------FHSGSPACSSNQSRER------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::** **: * : *: ** :. :*: ::::* :::: : ::***:*:* * :: : . : .. . . . . . . . : . . * . . . : : . ", "identical_positions": 17, "similar_positions": 47, "identity": "3.07%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010406-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUI9-1", "uniprot_id": "NCOA2_RAT", "id": "Q9WUI9-1", "name": "Nuclear receptor coactivator 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGMGENTSDPSRAETRKRKECP-DQLGPSP---KRSTEKRNREQENKYIEELAELIFANFNDIDNFNFKPDKCAILKETVKQIRQIKEQEK--------------------------------------------AAAANIDEVQKSDVSSTGQGVIDKDALG-------------PMMLEALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSMVN------------------------------------------------GGSWTGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQE---AHQKYETMQCFAVSQPKSIKEEGEDKQSCLICVAR-------RVPMKERPALPSSESFTTRQDLQGKITFLDTSTMRDAMKPGWEDLVRRCIQKFHTQHEGESLSYAKRHHHEVLRQG--------LAFSQIYRFSLSDG-TLVAAQTKSKLIRSQTTNEPQLVISIHMLHREQN------VCVMNPDLT-GQAMGKPLSPMSSSSPARQAMCSGNPGQDVALGSNMN-FPMNGPREQMSMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMN-SPSQSSPGLNPGQPSSVLSPRHRMSPGVAGSPRVPPSQFSPAGSLHSPAGVCSS-------TGNSHSYTNSSLNALQALSEGHGVSLGPSLASPDLKMGNSQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQAQASCHPEEQKRPNDSSMPQAASEDRAE---------------------------GHSRLHESKGQTKLLQLLTTKSDQME----------PSPLPSSLSDTNKDSTG----SLPGPGSTHGTS----LKEKHKILHRLLQDSSSPVDLAKLTAEATGKELNQESSG-----------------TAPGSEVTVKQEPAS---PKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTKLIAMKTVKEEVSFEPSDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPTGSVDKQAIINDLMQLTADSSP-VTPVGAQKAALRMSQSTFNNPR----PGQLGRLLPNQNLPLDITLQSPTGAGPFPPIRNSSPYSVIPQPGMMGNQGMLGSQGN------------------------------LGNNSTGMIGSSTSRSSMPSGEWAPQ---SPAVRVTCAATTGAMNRP---IQGGMIRNPTASIPMRANSQPGQRQMLQPQVMNIGPSELEMNMGGPQYNQQQAPPNQTAPWPESILP-----------------IDQASFGSQNRHPFGSSPDDLLCPHPAAESPSDEGALLDQLYLALRNFDGLEEIDRALG---------IPELVSQSQAVDPEQFSSQESSMMLEQKPP----VFP-QQYAS-QTQMAQGS--YNPMQDPNFH----TMGQRPNYTTLRMQPRPGLRPTGIVQNQPNQLRLQLQHRLQAQQNRQ----------PLMNQISGVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQM-----HQQQQVQQRTLMMRGQGLNMTPSMVAPTG-LPAAMSNPRIPQANAQQFPFPPNYG----------------------------------------------------------------------ISQQPDPGFTGATTPQSPLMSPRMAHTQSPMMQQSQ-----------------ANPAYQPASDINGWAQGSMGGNSMFSQQSPPHFGQQANTSMYNNN-MNINVSMATNTAGLSNMNQMTGQMSMTSVTSVPTSGLSSMGPEQVNDPALRGSSLFTTNQLPGMDMIKQEGDGSRKYC-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61026-1", "uniprot_id": "NCOA2_MOUSE", "id": "Q61026-1", "name": "Nuclear receptor coactivator 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGMGENTSDPSRAETRKRKECP-DQLGPSP---KRSTEKRNREQENKYIEELAELIFANFNDIDNFNFKPDKCAILKETVKQIRQIKEQEK--------------------------------------------AAAANIDEVQKSDVSSTGQGVIDKDALG-------------PMMLEALDGFFFVVNLEGSVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSMVN------------------------------------------------GGSWSGEPPRRSSHTFNCRMLVKPLPDSEEEGHDSQE---AHQKYEAMQCFAVSQPKSIKEEGEDLQSCLICVAR-------RVPMKERPTLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLVRRCIQKFHTQHEGESLSYAKRHHHEVLRQG--------LAFSQIYRFSLSDG-TLVAAQTKSKLIRSQTTNEPQLVISLHMLHREQN------VCVMNPDLT-GQAMGKPLNPISSSSPAHQALCSGNPGQDMTLGSNIN-FPMNGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMN-SPSQSSPGMNPGQASSVLSPRQRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSS-------TGNSHSYTNSSLNALQALSEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQAEASCHPEEQKGPNDSSMPQAASGDRAE---------------------------GHSRLHDSKGQTKLLQLLTTKSDQME----------PSPLPSSLSDTNKDSTG----SLPGPGSTHGTS----LKEKHKILHRLLQDSSSPVDLAKLTAEATGKELSQESSS-----------------TAPGSEVTVKQEPAS---PKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTKLIAMKTVKEEVSFEPSDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPTGSVDKQAIINDLMQLTADSSP-VPPAGAQKAALRMSQSTFNNPR----PGQLGRLLPNQNLPLDITLQSPTGAGPFPPIRNSSPYSVIPQPGMMGNQGMLGSQGN------------------------------LGNNSTGMIGSSTSRPSMPSGEWAPQ---SPAVRVTCAATTGAMNRP---VQGGMIRNPTASIPMRANSQPGQRQMLQSQVMNIGPSELEMNMGGPQYNQQQAPPNQTAPWPESILP-----------------IDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALLDQLYLALRNFDGLEEIDRALG---------IPELVSQSQAVDAEQFSSQESSIMLEQKPP----VFP-QQYAS-QAQMAQGG--YNPMQDPNFH----TMGQRPNYTTLRMQPRPGLRPTGIVQNQPNQLRLQLQHRLQAQQNRQ----------PLMNQISSVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQM-----QQQ--VQQRTLMMRGQGLNVTPSMVAPAG-LPAAMSNPRIPQANAQQFPFPPNYG----------------------------------------------------------------------ISQQPDPGFTGATTPQSPLMSPRMAHTQSPMMQQSQ-----------------ANPAYQPTSDMNGWAQGSMGGNSMFSQQSPPHFGQQANTSMYSNN-MNISVSMATNTGGLSSMNQMTGQMSMTSVTSVPTSGLPSMGPEQVNDPALRGGNLFP-NQLPGMDMIKQEGDASRKYC-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15596-1", "uniprot_id": "NCOA2_HUMAN", "id": "Q15596-1", "name": "Nuclear receptor coactivator 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGMGENTSDPSRAETRKRKECP-DQLGPSP---KRNTEKRNREQENKYIEELAELIFANFNDIDNFNFKPDKCAILKETVKQIRQIKEQEK--------------------------------------------AAAANIDEVQKSDVSSTGQGVIDKDALG-------------PMMLEALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSIVN------------------------------------------------GGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQE---AHQKYETMQCFAVSQPKSIKEEGEDLQSCLICVAR-------RVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLVRRCIQKFHAQHEGESVSYAKRHHHEVLRQG--------LAFSQIYRFSLSDG-TLVAAQTKSKLIRSQTTNEPQLVISLHMLHREQN------VCVMNPDLT-GQTMGKPLNPISSNSPAHQALCSGNPGQDMTLSSNIN-FPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMN-SPSQSSPGMNPGQPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSS-------TGNSHSYTNSSLNALQALSEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQAESSCHPGEQKETNDPNLPPAVSSERAD---------------------------GQSRLHDSKGQTKLLQLLTTKSDQME----------PSPLASSLSDTNKDSTG----SLPGSGSTHGTS----LKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESSS-----------------TAPGSEVTIKQEPVS---PKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTKLIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAIINDLMQLTAENSP-VTPVGAQKTALRISQSTFNNPR----PGQLGRLLPNQNLPLDITLQSPTGAGPFPPIRNSSPYSVIPQPGMMGNQGMIGNQGN------------------------------LGNSSTGMIGNSASRPTMPSGEWAPQ---SSAVRVTCAATTSAMNRP---VQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGGPQYSQQQAPPNQTAPWPESILP-----------------IDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALLDQLYLALRNFDGLEEIDRALG---------IPELVSQSQAVDPEQFSSQDSNIMLEQKAP----VFP-QQYAS-QAQMAQGS--YSPMQDPNFH----TMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQQNRQ----------PLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQM-----HQQQQVQQRTLMMRGQGLNMTPSMVAPSG-MPATMSNPRIPQANAQQFPFPPNYG----------------------------------------------------------------------ISQQPDPGFTGATTPQSPLMSPRMAHTQSPMMQQSQ-----------------ANPAYQAPSDINGWAQGNMGGNSMFSQQSPPHFGQQANTSMYSNN-MNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQVNDPALRGGNLFP-NQLPGMDMIKQEGDTTRKYC-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q98TW1-1", "uniprot_id": "NCOA2_DANRE", "id": "Q98TW1-1", "name": "Nuclear receptor coactivator 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAVGENSSDPARSEAQKRKEGPSDLLGPSP---KRSTEKRNREHESKYIEELAELIFANFNDIDNFNVKPDKCAILKETVKQIRQIKEQEK--------------------------------------------AAAANEDEVQKADVSSTGQSVIDKDALG-------------PMMLEALDGFFFVVNMEGNIVFVSENVTQYLRYNQEELMNTSVYSILHVGDHAEFIKNLLPKSHVN------------------------------------------------GVPWSSENPRRNSHTFNCRMLVN--PHSEAEETQDHE---AQQKYETMQCFAVSEPKSIKEEGEDFQSCLICVAR-------RVPMKERPMLPTQESFTTRQDLQGKITSLDTSLLRASMKPGWEDLVRRCIQRFHLQNDGD-ISFAKRHQQEVIRHG--------QAFSPIYRFSLSDG-TIVSAHTKSKLVRSSSTNEPQLYMSLHILQREQP------VCGMASDLGNAQTMGKPMNPMSSPNTAGSSCTP--QGQDATISSNTSTFPSPGAQKEPGA-MHRFGCPGTMSHSATMQAATPQGSGYPLKLS-SPSQGSPGM--------LSPRHRASPGVAGSPRLPPPQFSPAGSLHSPASMCTSSTGGNGGAGANHGYTSSSLNALQALSECHGVSHGQSLGSPDRKLGSPAAHSVAVSHHLINKMSVPES---FGEQNQSEQGTPGQDEGIDLPRDEKG----NLGQFGNLDGSD---------------------------PQSRLRDNKSHTKLLQLLTTKTEPIES-------TSPPPMAGGEPGCKDGGAGNGGMGSQGGNGSHATS----LKEKHKILHRLLQNSSSPVDLAKLTAEATGKELCQDSAGG----------------TAGVPELAIKQEPVS---PKKKDNALLRYLLDKDDNVLKGK---GIKMEPGEIKEE---GGKMTGIKTEKTDGGYDRVE-PSSELD---DILDDLQNSQ-PGLFTDSRPVSLPSAVDKQSIINDILQMTGESGANMSPQQQRALQTAVSQQNFPAPR----PGQPGRAPPVRSVSLDMNMPPKGAQGQYPMMRNNNPYSIMQQQGMMGNHAVMPNQPN------------------------------MVN--AGVMGNNGPRVGMQQDGWGAQGTVGSAASPATAAPAGQHSLPQGALHSRMVPNPATGMPMRPNSQPGPRPMLQPQMMANAQSNMDMGMAGHQFPQQQAPPNQTAPWPDSVMP-----------------IEPVPFGNQSSSMYGGSQEDVLCP-PASEGPADEGALLSQLYSALKDFDGLEEIDRALG---------IPALVGQAQPVEQDQFPGQDPSMMMDQKPP----MYGQQQYASSPANMQQAG--YTPMQDATFHGLQGQMGQRPGYPMLRMQARPGLRPGGVVPNQPNTLRLQLQHRLQAQQNRQ----------PMMNQMGGVSNMNLPLRPNVPNQGTINAQMLAQRQRELLSNHLRQRQLDQQRQQQQQQQQQRSLAMRAQGLTMPPNMAAAAAGMPGAMSNPRIPQANLQQFPYPPNYGTGLASPPPSTSPFSPGSPNLPAPQLLSHSAMHGSQMSLANQGMLGSLSGQFGAVMSPQMQHSAFQFPSSGMSQQSDGGFGGAATPQSPLMSPRMGHAQSPMMQQAQ-----------------GNSSFQSSPDMNGWPQGNINTNSMFTQQSPPQFSQQANNNMYNGNGMNLNVSMAANS---SNMGQMGNQMSMSSMNSGPGSGMANMGPEQQ------------------------------KYC-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9ND53-1", "uniprot_id": "M9ND53_DROME", "id": "M9ND53-1", "name": "", "aln": "MSIAAAENAGLSPSDLPDHWASGTSNPSTSTSSSSSSSISASGSNNNKYNSGNISVCNLPRSSPAAATAAVTLSSAAGGIGSNLLSGLHHGLAPGTHPLQRATAASGGGAGAGGVAGASTAAALTLQQHQHQQQQQQQQQQAQHQHQHQHQQQTQQQQLAYQHQQLQQQIISHRSIQNKAAATAAAQTANLAAALQRSAAIMNAVASPISANSANSATSGRKIRRKTDSKVNLPQSQINKCNNEKRRREAENGYIEQLSEILTLNK-RGDMTSTKPDKAAILNQVVRTYREICDKGQNRDISSTSTNNNNSTTTTNNNTNSNNNNNTSKPQATSTRCSRCATDNCSIHPVQQGEVSSTEPPLPEPSLLLGQVPEISAYFEALEHYISGVGWVLLQVNANGIIESCTQNIRDLIGYEKQELYHQPLYMYLYSGDHAKLEPIINTMYNNPNGGNSNSANNSGPGGSSAGTSAGVWGDLEELNNGNASQGSNSSGAGGLGGAGGAAAGKKRSISTKVRMLVKDTRTATQTSSNCEEKPLRQSGHQDKYEEVVLIAAPVKDDADASSSVLCLITRPEDESPLEINIQQHVQQQPIEQMTFKLDIHGKILTLDPTALREPFKQHLQTWVGRLWQDLCHPHDLSTLKSHLRDIQDSASANSPGAGAGTSVVSRPFRLRLGAPDVYVHVKANSRLFLNQTPGEGDFIMSVQTLLNSENDMNSSNTGAGSGGLGLGQLCAMAPSPSLASSLLSSLSMDGLHGGTGSGSSSSPAASGMLPTHLLGGLVGGGQQGGGGNSTQTTSVGGPLMSSAIINGTGLQQQQQQQQRSGASSSASSSANALVNAFTASPAPAEHSFYGSDTFEFDIAAHSSSFELDP-SGGVGAWTDSRPNSRASVATPVSTPRPPSGHGFSPAVCASPATPYQLSSHSAASLPSPQSNASAGGGNYGGFNFHSFDSSDVKPEKDVQQQQNQQQSNNNSSSSNPLLGGGLPNGVGGMLLSQQQQQQQTPPQQQQQQQQQESSERLRHLLTKSQSMAGGLGGLGDDEKYFKPEGSEEEKHASGGFKMGGQPGGMGMFGPMGSMGRGVGNSSMLHKAGNSQNPMLLKLLNEKSEDDDGNGSGGGPGSMNNSRQSELMRQLKNPDGGSHGMHRNSASGNMSTEDLKAMLKIQSDPSLNRKRSLNEPDDDPSAKRSEDKPSKLCTQNKMLAKLLQNPPKIPKAPNPEQPLQVKTLPDITSSTVSSTLAAPGNLISAGSTGPKAAANRNRKQQQQQQQQQQQQQQQQVAGIPSQQQQQQPNDVYLSQQQQQQLQSPQLAFQHQQLATTATTSITTAASTSAAAAAAAAILGEGDSELSKLLDSVMEYYPDDTPIVTNAPSEASAINDIQKSLMLDVESAAFGNDLNQQLMMTQQQQHQQ--QQQQQQLLALQLAQQQQQQRQQHLQQPPAYPGMLNMQQQQHQQQQQQNQQHIMQRLEAMRNQGNQGFQRPPPMYPARGRGPMNAVATPGGVVLPAQQQLRNIRQQQQLAAAQQKERLLQQQQKQQLLVPENASEYWGNSNLQLIIKLIVSYILAGMNAGLNNIGSLLNTTGAPNVSLSRTNLPSDAQLSPNFAQTLMQQQLSPGRSAPYSPQPNQGYAPQFPQPGQRLSPQQQQQLSQQQQNNVQQQQLAYQQQQVGDGGRSNTPFGSNSGMQSPGMQNSPQQWGSGGGGGGGPGGPLPSGNAGRTLQQHNPMLIAQLQGVSPYNARQYQQNQRRGLNSPGAVGPGGNP-AAQAALQRQNSFQGQGGGGATTPDGSGVGFGGPQSPYGTNVNVFQQQQLQRLQRQGS----------------------VPQATQHLPGSPRFGSSPGSSNNTDSSAAAGNQQQQQQQQQQQQQQHQQQQHQQLMNGLSMSPHPHPHPAMMGVGGMGSGGGNGIIGLGGGGGNYGATLGGYGQSQQANDFYGRAQTAGGGGSVAGGNANSEFVKQELRAVVSVR-AQQAAAAATGGAGVGGGVAQRGQTPQSPLQQGSVIGGGGGIVGGVNSTNTMGNVTPTGSGNVSNSMLNTPPDPTLSFSFETPDFFTSSATR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. *:::.: : : *:: . *.. * ..***.** *. ***:*:*:: * * . ****.***::.*: *:* :: : : .. . **:.:**** : : . * :..:. .:: ** :* : ::*: : : *:::** : .:* *: ***::: : . * . . :: * : : ****: : : .* :. :: .* . .:*::.: .* * ::* .: :::: . *.:* : *::*** **.: :* .:* : * * * : :: . :. *. :: . ..* :*: *. . * .:::*:*. ..:..* :: :*:: * ..: . .* .* . . .* : . . * : .*. . . . . : * . .. * *. :: . .* . *. : ..:.** . .* :.::. . :* :* .:*.* *: ::: ... * . . : . :. .: :* * . . . .. * .: . . . :: :.: ::.: :: *: * **:: : . . :. . * . * . ... :. : : :*..*: * *. :: ..: .... .. . ::::..* ..:. :*:*: * . . . . . : . . : : : . . *..* . * *: .* . :. . ..:.. :: * : :. : **. *. . * : .:.:: . . . .... : : ... : . : : : :. :*.. : * * * . . : . : *: ..: : * ::* : : . * * *.. .* * : .. .:. . :::* * *:* .:.. * . : *:: . :* * . : : .. .:* :* .* : * . .:: * . .* *: : *: . : * * *. . .:.. :*: * . * * :.: * * . : .. **: *.**. *.. * :*.:: :. * .*. . * : ...: : **: . * .** : : * : . * * * . . .: . * . *: * .* . .*: :: ..* :* : . . : .: *:. .. .* . :.: . . * . .:. ", "identical_positions": 195, "similar_positions": 482, "identity": "9.4%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010410-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48168-1", "uniprot_id": "GLRB_MOUSE", "id": "P48168-1", "name": "Glycine receptor subunit beta", "aln": "MKFSLAISFFILMSLLFEDACAKEKSSKKGKGKK-KQYLCPSQQSPEDLARVPPNSTSNILNRLLVSYDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQLEK-IALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQADGKGG-NAAKKNTVNGTG-TPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKPQAKN-KKPPPAKPVIPTAAKRIDLYARALFPFCFLFFNVIYWSIYL-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20781-1", "uniprot_id": "GLRB_RAT", "id": "P20781-1", "name": "Glycine receptor subunit beta", "aln": "MKFSLAVSFFILMSLLFEDACSKEKSSKKGKGKK-KQYLCPSQQSAEDLARVPPNSTSNILNRLLVSYDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQLEK-IALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQADGKGG-NAAKKNTVNGTG-TPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKPQAKN-KKPPPAKPVIPTAAKRIDLYARALFPFCFLFFNVIYWSIYL-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48167-1", "uniprot_id": "GLRB_HUMAN", "id": "P48167-1", "name": "Glycine receptor subunit beta", "aln": "MKFLLTTAFLILISLWVEEAYSKEKSSKKGKGKK-KQYLCPSQQSAEDLARVPANSTSNILNRLLVSYDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQLEK-IALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQADGKGG-NVAKKNTVNGTG-TPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKSQAKNNKKPPPAKPVIPTAAKRIDLYARALFPFCFLFFNVIYWSIYL-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TUJ6-1", "uniprot_id": "A0AB32TUJ6_DANRE", "id": "A0AB32TUJ6-1", "name": "Glycine receptor subunit beta", "aln": "MLRCAAMLLKGLILLMLLVQFSAEEGGKPKKGKKGKQVICPSQLSAEDLDRVPANSTSNILNRLLMTYDSRIRPNFKGIPVEDKVNIFINSFGSIQETTMDYRVNIFLRQRWNDPRLRLPTDFK-SDALTVDPKMFQCLWKPDLFFANEKNANFHDVTQENILLFIFRNGDVLISMRLSVTLSCPLALQLFPMDTQYCKMQLESFGYTTKDLVFMWQSGDPVQMDE-IALPQFDVKQEDIKYANCTKFYPGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGILSVLSLSSECTSLASELPKVSYVKAIDIWMIACLLYGFASLVEYAVVQVMLNSPKRIEAEKIKMAEKEKAREKENKTPAKTNSANGTGGTPIHVSTLQVVENRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNFDCYGKPIEVTDASGKPQNKNNKKPAPPKPVIPSAAKRVDLYARALFPFTFLFFNVIYWSVYL-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94900-1", "uniprot_id": "GLUCL_DROME", "id": "Q94900-1", "name": "Glutamate-gated chloride channel", "aln": "--MGSGHYFWAILYFASLCSASLANNAKINFREKEKKVLDQILGAGKYDARIRPSGINGTDG-----------------PAIVRINLFVRSIMTISDIKMEYSVQLTFREQWTDERLKFDDIQGRLKYLTLT--EANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRFTLEKFLTDYCNSKTN---TGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYAS----RSGSNKANMHKENMKKKRRD------------------------LEQASLDAASDLLDTDSNATFAMKPLVRHPGDPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRQCSRSKRIDVISRITFPLVFALFNLVYWSTYLFREEEDE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: : : :..* :* *: : : : *: ... .. . *. :*:*:.*: :*.: .*:* *:: :*::*.* **:: . **: : :* *****:***..:**:: *: : ** :*.** *:*:*:**:**: * *:*:* * *.::: *:*:**.** *:*:.*****: : : **:* ::: .* *... ** *:*::* : ::*:..:*:: :* * ::*::**:***:: .* .***.**: ::*::::: : : :.** ***.**:*:* .** : *.:*:*:*:*: * ::* .: : : : . * . ...:. * ** : .* *. . ** * . . . : :**:*: :* **: * :**::*** ** ", "identical_positions": 130, "similar_positions": 157, "identity": "25.59%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010410-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61603-1", "uniprot_id": "GLRA4_MOUSE", "id": "Q61603-1", "name": "Glycine receptor subunit alpha-4", "aln": "MTTLVPASLFLLLWTLPGKVLLSVALAKEDVKSGLKGSQ-PMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNVFLRQQWNDPRLAYREYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLESFGYTMNDLMFEWLEDAPAVQVAEGLTLPQFILRDEKDLGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFMRLRRRQRRQRMEEDIIRESR-FYFRGYGLGHCLQARDGGPMEGSSIYSPQPPTPLLKEGETMRKLYVDRAKRIDTISRAVFPFTFLVFNIFYWVVYKVLRSEDIHQAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1RDZ6-1", "uniprot_id": "F1RDZ6_DANRE", "id": "F1RDZ6-1", "name": "", "aln": "MLPQVIRILYVLSFFFFQGGFIRLGSCKEEIKSSSRPAQKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQQWNDPRLAYSEYPDASLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQNGNVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLESFGYTMNDLIFEWLSDNP-VQVADDLTLPQFVLKEEKDLGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFIRLRKKQRRQRIEEELVRESRGFYFRGYGLGHCLQTKDGTAVEGSSVFAPPPPVQVLYDGEAVRKRFVDRAKRIDTISRAVFPLSFLIFNVFYWITYKVLRHEDIHANP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . * *::* : : :: :. .**::**. : :* ********************************************:********:*************** **** ****************************************:********************************************:****.* * ****:.******:*::***************************************************************************************************************************:***::*****:**:::**** *************::** .:****:::* **. :* :**::** :****************::**:**:***:.***** **** ", "identical_positions": 377, "similar_positions": 51, "identity": "82.31%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010413-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43308-1", "uniprot_id": "SSRB_HUMAN", "id": "P43308-1", "name": "Translocon-associated protein subunit beta", "aln": "MRLLSFVVLALFAVT---QAEEGARLLASKSLLNRYAVEGRDLTLQYNIYNVGSSAALDVELSDDSFPPEDFGIVSGMLNVKWDRIAPASNVSHTVVLRPLKAGYFNFTSATITYLAQEDGPVVIGSTSAPGQGGILAQREFDRRFSPHFLDWAAFGVMTLPSIGIPLLLWYSSKRKYDTPKTKKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F8W477-1", "uniprot_id": "F8W477_DANRE", "id": "F8W477-1", "name": "Translocon-associated protein subunit beta", "aln": "MKMRILCIFALVAVVGLVAGEEGARLLASKSLLNRYAVEGRDLTLQYSIYNVGTSAALEVELSDDSFPPEDFGIVSGMLNVKWDRIAPASNVSHTVVLRPLKAGYFNFTSASVSYLAQEGGQVVVGYTSAPGQGGILAQREFDRRFSPHYLDWAAFGVMTLPSIGIPLLLWYSSKRKYDSPKSKKN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: : ::**.**. .***************************.*****:****:****************************************************:::*****.* **:* **********************:*****************************:**:***", "identical_positions": 158, "similar_positions": 19, "identity": "84.95%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010426-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P11532-1", "uniprot_id": "DMD_HUMAN", "id": "P11532-1", "name": "Dystrophin", "aln": "--------MLWWEEVEDCY---------EREDVQKKTFTKWVNAQFSKFGKQHIENLFSDLQDGRRLLDLLEGLTGQKLPKEKGSTRVHALNNVNKALRVLQNNNVDLVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNVMKNIMAGLQQTNSEKILLSWVRQSTRNYPQVNVINFTTSWSDGLALNALIHSHRPDLFDWNSVVCQQSATQRLEHAFNIARYQLGIEKLLDPEDVDTTYPDKKSILMYITSLFQVLPQQVSIEAIQEVEMLPRPP-KVTKEEHFQLHHQMHYSQQITVSLAQGYERTSS--PKPRFKSYAYTQAAYVTTSDPTRSPFPSQHLEAPEDKSFGSSLMESEVN-LDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIGTGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQNQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWTEDRWVLLQDILLKWQRLTEEQCLFSAWLSEKEDAVNKIHTTGFKDQNEMLSSLQKLAVLKADLEKKKQSMGKLYSLKQDLLSTLKNKSVTQKTEAWLDNFARCWDNLVQKLEKSTAQISQAVTTTQPSLTQTTVMETVTTVTTREQILVKHAQEELPPPPPQKKRQITVDSEIRKRLDVDITELHSWITRSEAVLQSPEFAIFRKEGNFSDLKEKVNAIEREKAEKFRKLQDASRSAQALVEQMVNEGVNADSIKQASEQLNSRWIEFCQLLSERLNWLEYQNNIIAFYNQLQQLEQMTTTAENWLKIQPTTPSEPTAIKSQLKICKDEVNRLSDLQPQIERLKIQSIALKEKGQGPMFLDADFVAFTNHFKQVFSDVQAREKELQTIFDTLPPMRYQETMSAIRTWVQQSETKLSIPQLSVTDYEIMEQRLGELQALQSSLQEQQSGLYYLSTTVKEMSKKAPSEISRKYQSEFEEIEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPALGDSEILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEAEPEFASRLETELKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEYLERDFEYKTPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKKELETLTTNYQWLCTRLNGKCKTLEEVWACWHELLSYLEKANKWLNEVEFKLKTTENIPGGAEEISEVLDSLENLMRHS-EDNPNQIRILAQTLTDGGVMDELINEELETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHLIQESLTFIDKQLAAYIADKVDAAQMPQEAQKIQSDLTSHEISLEEMKKHNQGKEAAQRVLSQIDVAQKKLQDVSMKFRLFQKPANFEQRLQESKMILDEVKMHLPALETKSVEQEVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQKKQTENPKELDERVTALKLHYNELGAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWGKATQKEIEKQKVHLKSITEVGEALKTVLGKKETLVEDKLSLLNSNWIAVTSRAEEWLNLLLEYQKHMETFDQNVDHITKWIIQADTLLDESEKKKPQQKEDVLKRLKAELNDIRPKVDSTRDQAANLMANRGDHCRKLVEPQISELNHRFAAISHRIKTGKASIPLKELEQFNSDIQKLLEPLEAEIQQGVNLKEEDFNKDMNEDNEGTVKELLQRGDNLQQRITDERKREEIKIKQQLLQTKHNALKDLRSQRRKKALEISHQWYQYKRQADDLLKCLDDIEKKLASLPEPRDERKIKEIDRELQKKKEELNAVRRQAEGLSEDGAAMAVEPTQIQLSKRWREIESKFAQFRRLNFAQIHTVREETMMVMTEDMPLEISYVPSTYLTEITHVSQALLEVEQLLNAPDLCAKDFEDLFKQEESLKNIKDSLQQSSGRIDIIHSKKTAALQSATPVERVKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLTEAEQFLRKTQIPENWEHAKYKWYLKELQDGIGQRQTVVRTLNATGEEIIQQSSKTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASIPLEPGKEQQLKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDVKETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVKRKLEDLSSEWKAVNRLLQELRAKQPDLAPGLTTIGASPTQTVTLVTQPVVTKETAISKLEMPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLRELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11531-1", "uniprot_id": "DMD_MOUSE", "id": "P11531-1", "name": "Dystrophin", "aln": "--------MLWWEEVEDCY---------EREDVQKKTFTKWINAQFSKFGKQHIDNLFSDLQDGKRLLDLLEGLTGQKLPKEKGSTRVHALNNVNKALRVLQKNNVDLVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNVMKTIMAGLQQTNSEKILLSWVRQSTRNYPQVNVINFTSSWSDGLALNALIHSHRPDLFDWNSVVSQHSATQRLEHAFNIAKCQLGIEKLLDPEDVATTYPDKKSILMYITSLFQVLPQQVSIEAIQEVEMLPRTSSKVTREEHFQLHHQMHYSQQITVSLAQGYEQTSSS-PKPRFKSYAFTQAAYVATSDSTQSPYPSQHLEAPRDKSLDSSLMETEVN-LDSYQTALEEVLSWLLSAEDTLRAQGEISNDVEEVKEQFHAHEGFMMDLTSHQGLVGNVLQLGSQLVGKGKLSEDEEAEVQEQMNLLNSRWECLRVASMEKQSKLHKVLMDLQNQKLKELDDWLTKTEERTKKMEEEPFGPDLEDLKCQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWTEDRWIVLQDILLKWQHFTEEQCLFSTWLSEKEDAMKNIQTSGFKDQNEMMSSLHKISTLKIDLEKKKPTMEKLSSLNQDLLSALKNKSVTQKMEIWMENFAQRWDNLTQKLEKSSAQISQAVTTTQPSLTQTTVMETVTMVTTREQIMVKHAQEELPPPPPQKKRQITVDSELRKRLDVDITELHSWITRSEAVLQSSEFAVYRKEGNISDLQEKVNAIAREKAEKFRKLQDASRSAQALVEQMANEGVNAESIRQASEQLNSRWTEFCQLLSERVNWLEYQTNIITFYNQLQQLEQMTTTAENLLKTQSTTLSEPTAIKSQLKICKDEVNRLSALQPQIEQLKIQSLQLKEKGQGPMFLDADFVAFTNHFNHIFDGVRAKEKELQTIFDTLPPMRYQETMSSIRTWIQQSESKLSVPYLSVTEYEIMEERLGKLQALQSSLKEQQNGFNYLSDTVKEMAKKAPSEICQKYLSEFEEIEGHWKKLSSQLVESCQKLEEHMNKLRKFQNHIKTLQKWMAEVDVFLKEEWPALGDAEILKKQLKQCRLLVGDIQTIQPSLNSVNEGGQKIKSEAELEFASRLETELRELNTQWDHICRQVYTRKEALKAGLDKTVSLQKDLSEMHEWMTQAEEEYLERDFEYKTPDELQTAVEEMKRAKEEALQKETKVKLLTETVNSVIAHAPPSAQEALKKELETLTTNYQWLCTRLNGKCKTLEEVWACWHELLSYLEKANKWLNEVELKLKTMENVPAGPEEITEVLESLENLMHHS-EENPNQIRLLAQTLTDGGVMDELINEELETFNSRWRELHEEAVRKQKLLEQSIQSAQEIEKSLHLIQESLEFIDKQLAAYITDKVDAAQMPQEAQKIQSDLTSHEISLEEMKKHNQGKDANQRVLSQIDVAQKKLQDVSMKFRLFQKPANFEQRLEESKMILDEVKMHLPALETKSVEQEVIQSQLSHCVNLYKSLSEVKSEVEMVIKTGRQIVQKKQTENPKELDERVTALKLHYNELGAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDTELTKRSAVEGMPSNLDSEVAWGKATQKEIEKQKAHLKSVTELGESLKMVLGKKETLVEDKLSLLNSNWIAVTSRVEEWLNLLLEYQKHMETFDQNIEQITKWIIHADELLDESEKKKPQQKEDILKRLKAEMNDMRPKVDSTRDQAAKLMANRGDHCRKVVEPQISELNRRFAAISHRIKTGKASIPLKELEQFNSDIQKLLEPLEAEIQQGVNLKEEDFNKDMSEDNEGTVNELLQRGDNLQQRITDERKREEIKIKQQLLQTKHNALKDLRSQRRKKALEISHQWYQYKRQADDLLKCLDEIEKKLASLPEPRDERKLKEIDRELQKKKEELNAVRRQAEGLSENGAAMAVEPTQIQLSKRWRQIESNFAQFRRLNFAQIHTLHEETMVVTTEDMPLDVSYVPSTYLTEISHILQALSEVDHLLNTPELCAKDFEDLFKQEESLKNIKDNLQQISGRIDIIHKKKTAALQSATSMEKVKVQEAVAQMDFQGEKLHRMYKERQGRFDRSVEKWRHFHYDMKVFNQWLNEVEQFFKKTQNPENWEHAKYKWYLKELQDGIGQRQAVVRTLNATGEEIIQQSSKTDVNILQEKLGSLSLRWHDICKELAERRKRIEEQKNVLSEFQRDLNEFVLWLEEADNIAITPL--GDEQQLKEQLEQVKLLAEELPLRQGILKQLNETGGAVLVSAPIRPEEQDKLEKKLKQTNLQWIKVSRALPEKQGELEVHLKDF-------RQLEEQLDHLLLWLSPIRNQLEIYNQPSQAGPFDIKEIEVTVHGKQADVERLLSKGQHLYKEKPSTQPVKRKLEDLRSEWEAVNHLLRELRTKQPDRAPGLSTTGASASQTVTLVTQSVVTKETVISKLEMPSSLLLEVPALADFNRAWTELTDWLSLLDRVIKSQRVMVGDLEDINEMIIKQKATLQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQIQWDEVQEQLQNRRQQLNEMLKDSTQWLEAKEEAEQVIGQVRGKLDSWKEGPHTVDAIQKKITETKQLAKDLRQRQISVDVANDLALKLLRDYSADDTRKVHMITENINTSWGNIHKRVSEQEAALEETHRLLQQFPLDLEKFLSWITEAETTANVLQDASRKEKLLEDSRGVRELMKPWQDLQGEIETHTDIYHNLDENGQKILRSLEGSDEAPLLQRRLDNMNFKWSELQKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDIHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNAEWDKLNLRSADWQRKIDEALERLQELQEAADELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVNRVNDLAHQLTTLGIQLSPYNLSTLEDLNTRWRLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSESMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNAPGKPMREDTM------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IXX0-1", "uniprot_id": "A0A0R4IXX0_DANRE", "id": "A0A0R4IXX0-1", "name": "Dystrophin", "aln": "MAEAVNPQDQWEEGFEDEFGEIIKTRSDEREDVQKKTFTKWINSQFAKTRRPPIDDLFTDLCDGRRLLELLEVLVGHEIVKERGFTRVHSLNNVNRALQILQKNNVDLVNIGGADIVDGNHKLTLGLIWSIILHWQVKDVMKDVMADLQQTNSEKILLSWVRQSLKNYQDVNVVNFSSSWADGFAFNALIHSHRPELFSWSVVEQQDNAIERLDHAFGVAEKSLGIDRLLDPEDVATVHPDKKSIIMYVTSLFKVLPHGVSLEAIQEVETLPRAA--VTKEEHVLYQTQQRYSQQITVSVAQSRVRSPSPSYKPRFKSYAFTQAAYVKTPEQQRKFLIAQSPDKADELRPSPSPLPQGLNELESYQSALEEVLTWLLSAEDGLQAQPPISSFVEEVKEQFHTHEGYMVELTSHQGSVGRVLKAGSVLLSGGQLTDDEEREVREQMNLLNSRWEHLRVASMERQSRLHEVLMDLQHQQLKQLSDWLDTTETRIKRMGAQALGPELDDIKRQIEEQKLLQEDLELEQVRVNSLTHMVVVVDENSGDGATAALEEKLQNLGERWAAICKWTEERWILLQKILLCWQHFSEEQLLFDSWLTQKEELVQSIQSSGTNDPNEVAANLRKLAILKADLELKRQTMDKLCSLVQDLLTNIKSKEAAGKLEAKLERFAQRWDKLVQALQLTSTKISTIVTTSQSEITHTT-MATVTKVTTNQKKMVKHTKEGMSTPPPQKKRQIVVDSELRKRFDVDFTEIHSFMTRSEAVLQNPEFSISRKEGSVADLYEKVLAIDREKPEKFRKLQEATRSAQALVDQLTSDGQNSEDIQQAAQQLRARWVDFCALLAERLAWLAYQTKVLAFYNLFQQLEQAAATAENWLKVQSPPACEPEPLRIQLERCRDEISRLSALQPQVAKLHEQLEELRQKEETPVLFDADISAFQEHYHQVLEDLRARERQLVLVQSSLPPARYKDVMAALLAWLQQCENKLAIPSTAVTEYPVMEQRLKDIKAIQASQKEHQGDVDDLNKMAEQVFQKAPPEICQKYRTELDNVMVRWRRISEQLEENIQKLQDHMTKLQQFQNDTKTLQKWMAEVDVFLNEEWPALGDAEALEKQLEQCTALVNDIHTVQPSLNGINEVGLALKREAETPFAIKIQKMLDELNAQWELICKQAYAKKSALKGGLDMTVSLRKEMQEMQEWITQAEEEYLERDFQYKTPEELHKAVEELKRAQEEVHQKETKVKLLTDKVTNFISKAPPAAHDALKAELDVLTSNYQRLCSRLDGKCKTLEEVWACWCELLSYLELENAWMDLLEKKLDETEGLQGGIEEIEEALTSLDTMIREHPEYNRNQIRELAQTLMDGRVLDELIHKKVEDYNTRWDELMQRASQRRQQLEKSLHWAQENDKTLRLIQDSLNTTDRHLTAYIADGIDAAQIPQEAQKIQTELNGHEVTLDDMKKKAMEVDASEKVIGEIDATLDKLLQVKGKFRLFQKPANFDQRLRECERVLEEVKVKLGVLSIRSVEQEVVQSQLEQCMKFYKNLSEVKSEVETVIKTGRQIVQKQQTEQPKELDDRLTALKLAYNDLGSQVTEGKQELEKILKLLRKFRKEVNSLTEWLATTDGELTRRSSVEGMPSDLDAELAWAKAAQEDTEHHKPQLKLVRELAGTLKGLLHSQENLIDDKVSLLNCNWIAVTSRSEQWLKLLLDYQNQMKTLEQNISQINTWMDRAEEKLDEMDSQ--GCIEHVIKGLRMELEEMKGKVEAVQVLAEDLIKNTGEHCKAQVKPKLEQLNQRFDIVARRILMGQASS--QELDEYHRQANIWLQVLDEEIKLGESLKEEDFLEDATID-EEALNELFLKGENLLKRTPGGEKREAVREKHNLLHDRYDTLKNLRALRKKKALALASQWYQFCKKSDDMMQWLDRIEKSIRELPDPPEEPRVKAVGYEIDQQRPKLEDLRGLGRVLSEGGASRMVEPRLLPINKRWTELDVNFTRVR--------------------------------HKSELQFLLQCISENEALLNSPERWSTAFINLPQQEKCLKEVKVNLDKLEG---------PVAEAVGRGASQPEEGLLVQLLRTNWENLKMLYQDR----LKRLEKAKKFNEELKMLDNWLTDAERTIMKYEQ----DPINNRDHLKELQAGLEKQEAAVKGLNALGTDLSPQCSKDDRDHIKQQLASINSRWAKVSNQLTEIKRRSAGAKMLLAELNEDMGEFQSWLDDAEAVAALPVEAGRKEQLSATLEKVKARVVELPSRKQALHQINSKG------SSLPADKVKPLEKQLKVINMRWAKVSTDLPEKQRQIEDLLRDLS-------LYQEQLSKLSIWASNTKTQLEQSPTAVDP------KIEDDVKEKKPAVETLLAK------ERPPCQPEKGQYDGLSADWTSIQVLLKDWKDKCQLAAVTLTGSAAG-------------------------------DAALDKFNKSWTELDDWLALLDHMVQTQRVMVGDLDEINEMTVKLKSALQDMEQRCPQLNKQITAAQNLKNKTNNPETRATITDRIEKLQAHWEDSHAKLTARVLTLQNMYKDSSDWLEARKRVEPLIKKANEKLESWKKVSHSVEDLKGQNADVKQLSKDLQQWQTQMNVTNELANKLLTLYADDDTSKVKQMTESMNLAWANIKKRAGDKEADLEAGLRQLQHYYLDLEKFLNWLTEAETTANVLQDATFKEGLLENPATVRHLLEQWQDLQAEIDAHRETYHSLDENGHRIVSSLEGTDNAVVLQKRLDDMGQRWHELCNKVMSIRPYLDAGVDQWKHLHMSLQELLNWLQLKREELEKQKPVGGDVPTVHQQLLTHKAFRRELGAKEPVINGTLDNAKTFLAEMPREGLKQRPGQ-KDVSPEERVQNVGRILRKEVEDVTVRWKNLGAASVDWQQQLELALERLMELQDAQDQLDYKLRQAESVKNSWKPVGELLVDDLQNHIDRVKAFQEEIAPIQDNVNHVNQLASTFRPSDIQLSPDNLSRIDDLNMRWRLLQISIEEHLSQLTTAFKDLGPS-QNFLHASVESPLERSISPNNVPYYINHQTQTTCWDHPKMAELYQSLADLNNVRFSAYRTAMKLRRMQKALCLDLLSMPAACEAFEQHNLKQNEQFMDIVQVINCLTSIYDRLEQQHSSLVNVPLCVDMCLNWLLNVYDTGRAGKIRTLSFKTGIISLCKAHLEDKYRFLFREVASATGFCDQRRLGLLLHDAIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPELEASVFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMQYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTILEGDNMETPVTLINFWPVDHPPASSPQLSHDDTHSRIEHYASRLAEMENRNGSYVNDNVSPNESMDDEHLLIQHYCQSLNQGSPLSQPQSPAQILISMETEEKGELERVLNDLEQENRKLQAEYDRLKKAHDHKGLSPLPSPPQMLPVSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLTRLRQLLEQPQTESKVNGTALSSPSTASPRSDTS-LASLRVAASQTTETMGDDELSSPTQDASTGLEDVIEQLNNSFPHSQGPNVGSLFHMVDNIGHAMESLVHVITEEQDLD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * .** : *************:*:**:* : *::**:** **:***:*** *.*::: **:* ****:*****:**::**:*********.:***************.********:*** :**.***************** :** :***:**::**:**:*:*********:**.*. * *..* :**:***.:*. .***::******* *.:******:**:****:***: **:******* ***.. **:***. : * :********:**. ::.* ********:****** *.: :. :* : . : ..* : :* *: **:******:******* *:** **. ** **:***:***:*::**:*** **.:*: ** *:. *:*::*** **:*********** *******:**.**.******:*:**:*.*** .** * ::* :.:**:*:*:* *::::*:****** *****************.*** *******:*: **:*** **:***:**::**.*** **:::*** **.:**::**: ::.*:::* :* **: :.*:*:: ** *** *: :* ** ** ****: :*.*..: * * ::.**: **:*.* *: ::::** ***:*..:*:** * *** ***.:: :***::* :..*********.****:***:***:**:**::********..**:: ****..:** *** ** ***.*******:*:*******:*:..:* *::.*:**::**.:** :** **:**: ** **.::::*** :***** ::**** ** *... .** .:: **: *:**:.*** ****: :*: * *::* : *:::***: ** :*:::::..::*:*::* : .:*** **::.*::: :*:**.*.**::* :**:* :**:** .::*:*:* :*:*... *. .::: :***.**.:** :*:::: :*:::*.** * ***:::*.**:::**. :**:**********:********:* *:***:** **.**:*:*****.:** * :* *** ** :::. * ***:**: :*:*.*::*.***.**: ****:*::.**:**:************:****:**:.****:***:**. ***:******:.*...*::*** *::*** **:.**:*** **:**:************* ******* * *:: :* **. *.: .* *** *.* **:.:::. * * **** ***** ** *:****::::* :*:** ** :.* :::: **:*:: *** :*:*:***:** *::*:***:* :****:********::*..**::*::***: :* ::*:.:**.: .** :*. ***********:***.*.: :*:***::* .*. :******:****.:*:::**.********* ***********:***:*****:*:***** **:**::*** **:*** *** **:***:* ******:** ***:**:******:**:*:**.**:*:: *::* :** : *:. :** :* .:*.*::**:****.******** *:**:***:**::*:*::**:.:*..*: :*: *** :.: *.::* *: *::::: **::.: * .*: * *:**: *:*::.:**:** :::** *:** :**:::: : : *: *: **: * .****** :* . * * :::**: :*:** :* .. .*** :: *::**: ::::**:**: *:**** :: ****: :::**::: ** ***.: .**:* :* ::* :. *::::: :*: :* .. ***.**: *** : :.*** ::: :*::.* : :*: .: *.: * : ***:*: :. * :* :**:.**::* .*:: .* ..* . .: : : : : *::: :*::* : :** ::*: ::*::::**.:.*: : * : : : : :***** *: ::::.*: *** * :: *.** * . ::::*.*:. ** .:.::*:: ::* * :*:*::.*:.** **::*: :* *: * ::**. **:** . *** *: *:*:*..* :.: .:: . **::** *::* *** ***** ::* ::*: :***.:* :* * :.*** . : : * *: *:. ** :*:* *:*. ** * : :.* ::* ::: **:: : * * *: .*. .** .**::**** ***:***:::::********::**** :* *:::**:*** ***:: ***********.* *:*: ******::* :*:: : :* * *::* ***::****::..* :: :.. **:***: .::*: :: : ::.***:***:* * .::*:*:** *** *: *** **: :**.:* :* .*:**..::** ** * **:: ******* *:*************: ** ***:. *:.*:: *****.**::* : **.****.::*: ****:*:* :**:***:*. :* ** :* :.**.:*:*. ****:**:****** ***** :**.:* *:***.*:*::* *:**:*** :***** .**:..: **:* * ***:: : :::.****.*** *:***:.*:*...*.:*. *.***:::: :**** ***:* *:** ****** :*.**:***:**:*.**:*:::***:: ****:::**.:**:** : . .***** *** ::*** **:***:::*::: ** *.:*:**: *:** :**:.* **:****:*******:***********:*************************:**********:.***:*::*******:* ***:*:*****:*******:*..***********************:*:**.********************:**::***:***************:**********************************:**::************************************************************************:**********************************************:******************* .**************************** ****:**.:*****:****************.******:********:*:**:*****:* ***:***:*********: *:***********:*:*.****************************************** **********:*:*****::*****: ***:* ***..***:::**:::* **.**:*****:*:******** *:* *. . *.: ", "identical_positions": 2038, "similar_positions": 1015, "identity": "54.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010426-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97784-1", "uniprot_id": "CRY1_MOUSE", "id": "P97784-1", "name": "Cryptochrome-1", "aln": "---MGVNAVHWFRKGLRLHDNPALKECIQGADT------IRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMTPLSDDHDEK----YGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQLSRYRGLGLLASVPSNSNGNGGLMGYAPGENVPSCSSSGNGGLMGYAPGENVPSCSGGNCSQGSGILHYAHGDSQQTHSLKQGRSSAGTGLSSGKRPSQ---EEDAQSVGPKVQRQSSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q32Q86-1", "uniprot_id": "CRY1_RAT", "id": "Q32Q86-1", "name": "Cryptochrome-1", "aln": "---MGVNAVHWFRKGLRLHDNPALKECIQGADT------IRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCTTPLSDDHDEK----YGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQLSRYRGLGLLASVPSNPNGNGGLMGYAPGENVP---SGGSG---------------GGNCSQGSGILHYAHGDSQQTNPLKQGRSSMGTGLSSGKRPSQ---EEDAQSVGPKVQRQSSN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16526-1", "uniprot_id": "CRY1_HUMAN", "id": "Q16526-1", "name": "Cryptochrome-1", "aln": "---MGVNAVHWFRKGLRLHDNPALKECIQGADT------IRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLISKMEPLEIPVETITSEVIEKCTTPLSDDHDEK----YGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQLSRYRGLGLLASVPSNPNGNGGFMGYS-AENIP----GCSS---------------SGSCSQGSGILHYAHGDSQQTHLLKQGRSSMGTGLSGGKRPSQ---EEDTQSIGPKVQRQSTN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N1TWC6-1", "uniprot_id": "A0A8N1TWC6_DANRE", "id": "A0A8N1TWC6-1", "name": "Cryptochrome-1", "aln": "---MVVNTVHWFRKGLRLHDNPSLRDSIKGADN------LRCVYILDPWFAGSSNVGISRWRFLLQCLEDLDASLRKLNSRLFVIRGQPTDVFPRLFKEWKISRLSYEYDSEPFGKDRDAAIRKLATEAGVEVFVRISHTLYDLDKIIEFNGGQSPLTYKRFQTLISRMDPVEMPAETITAEIMGKCSTPVSDDHDDK----FGVPSLEELGFETEGLSTAVWPGGETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYRKVKKNSTPSLSLYGQLLWREFFYTAATNNPHFDKMEFNPICVQIPWDRNPEALAKWAEGQTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSVNAGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDYIRRYLPILRGFPAKFIYDPWNAPESVQKVAKCIIGVHYPKPMVNHAEASRINIERMKQIYQQLSCYRGLGLLATVPSNTANNEDSNGAGPSSGDT---QERTHITVHTLPASSQSEFPAFAVSCGQQLVNSVQPQPGYSGAGMVGQAHKQTQRVRGMTAFKRHGEDRTTDFPSKIQRNDCN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0E8P0-1", "uniprot_id": "Q0E8P0_DROME", "id": "Q0E8P0-1", "name": "", "aln": "MDSQRSTLVHWFRKGLRLHDNPALSHIFTAANAAPGKYFVRPIFILDPGILDWMQVGANRWRFLQQTLEDLDNQLRKLNSRLFVVRGKPAEVFPRIFKSWRVEMLTFETDIEPYSVTRDAAVQKLAKAEGVRVETHCSHTIYNPELVIAKNLGKAPITYQKFLGIV---EQLKVPKVLGVPEKLKNMPTPPKDEVEQKDSAAYDCPTMKQLVKRPEELGPNKFPGGETEALRRMEESLKDEIWVARFEKPNTAPNSLEPSTTVLSPYLKFGCLSARLFNQKLKEIIKRQPKHSQPPVSLIGQLMWREFYYTVAAAEPNFDRMLGNVYCMQIPWQEHPDHLEAWTHGRTGYPFIDAIMRQLRQEGWIHHLARHAVACFLTRGDLWISWEEGQRVFEQLLLDQDWALNAGNWMWLSASAFFHQYFRVYSPVAFGKKTDPQGHYIRKYVPELSKYPAGCIYEPWKASLVDQRAYGCVLGTDYPHRIVKHEVVHKENIKRMGAAYKVNREVR--------------------------------------------------------TGKEEESSFEEKSETS--------------TSGKRKVR-----RATGSAPKRKR----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **************:* . : .*: :* ::**** : . :** .***** * ***** .**********:**:*::****:**.*.: *: * * **:. ****::***. **.* .: ***:*: : :* * *:.*:**::* :: : :::* ..: : : ** .*: ::* :. *::::* .: *.. :******** *:*. *: : ***.**:*. .*** .*.* *****:*****.*** **.:: :: *:* *.:** ***:****:**.*: :*.**:* * *:****:.:*: * *:.*:**:*:***** ******************************** :***:**** **::***.*****.*:**:*:*: *.**.**::***:*.***:*:* * :** **:**:*. *:. *::*..**: :*:* . : **:** *: * *. . .. : * : : . .* :* ", "identical_positions": 255, "similar_positions": 148, "identity": "41.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010426-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q16526-1", "uniprot_id": "CRY1_HUMAN", "id": "Q16526-1", "name": "Cryptochrome-1", "aln": "---MGVNAVHWFRKGLRLHDNPALKECIQGADT------IRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLISKMEPLEIP-VETITSEVIEKCTTPLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQLSRYRGLGLLASVPSNPNGNGGFMGYS------AENIPG-CSSSGSCSQG------------------SGILHYAHGDSQQ-------------------------------THLLKQGRSSMGTGLSGGKRPSQ-EEDTQSIGPKVQRQSTN----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P943-1", "uniprot_id": "A0A8M1P943_DANRE", "id": "A0A8M1P943-1", "name": "", "aln": "---MAPNSIHWFRKGLRLHDNPALQEAVRGADT------VRCVYFLDPWFAGSSNLGVNRWRFLLQCLDDLDSNLRKLNSRLFVVRGQPANVFPRLFKEWKISRLTFEYDSEPFGKERDAAIKKLAMEAGVEVIVKTSHTLYNLDKIIELNGGQPPLTYKRFQTLISRMDPPEMP-VETLSNSIMGCCVTPVSEDHGDKYGVPSLEELGFDIEGLPSAVWPGGETEALTRIERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYRKVKKTSTPPLSLYGQLLWREFFYTAATTNPRFDKMEGNPICVRIPWDKNPEALAKWAEAKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSVNAGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDFIRRYLPILRGFPAKYIYDPWNAPDSVQAAAKCIIGVHYPKPMVNHAEASRLNIERMKQIYQQLSRYRGLGLLASVPSTHNGNGNGMAYSPGEQQSGTNTPAPAVSSGSVASGNRSGSILLNFDSEEHQGPSGIQQQHQQQQQQQQQQQLGYHHMPDSGHNSRFYKSNVSHDMAAGHLLHKGGSVTGKRERESERDLDGEDESLSTSHKLQRQIAEVTSVYASSGNQSSMRS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0E8P0-1", "uniprot_id": "Q0E8P0_DROME", "id": "Q0E8P0-1", "name": "", "aln": "MDSQRSTLVHWFRKGLRLHDNPALSHIFTAANAAPGKYFVRPIFILDPGILDWMQVGANRWRFLQQTLEDLDNQLRKLNSRLFVVRGKPAEVFPRIFKSWRVEMLTFETDIEPYSVTRDAAVQKLAKAEGVRVETHCSHTIYNPELVIAKNLGKAPITYQKFLGIVEQLKVPKVLGVPEKLKNMPTPPKDEVEQKDSAAYDCPTMKQLVKRPEELGPNKFPGGETEALRRMEESLKDEIWVARFEKPNTAPNSLEPSTTVLSPYLKFGCLSARLFNQKLKEIIKRQPKHSQPPVSLIGQLMWREFYYTVAAAEPNFDRMLGNVYCMQIPWQEHPDHLEAWTHGRTGYPFIDAIMRQLRQEGWIHHLARHAVACFLTRGDLWISWEEGQRVFEQLLLDQDWALNAGNWMWLSASAFFHQYFRVYSPVAFGKKTDPQGHYIRKYVPELSKYPAGCIYEPWKASLVDQRAYGCVLGTDYPHRIVKHEVVHKENIKRMGAAYKVNREVR------------TGKEEESSFE--------------EKSETSTSG-----------------------------------------------------------------KRKVRRATG------------------SAPKRKR--------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :***************.. . .*:: :* :::*** : . ::* ****** * *:*** :**********:**:**:****:**.*.: *::* * **:. ****::*** **.* .: ***:*: : :* * *:.*:**::* ::.::. :: * ..: :.:... *. *::::* : * . :******** *:*. *: : ***.**:*. .*** .*.* *****:*****.*** **.:: :: * * **:** ***:****:**.*: :*.**:* ** *::***:::*: * *:..:**:*:***** ******************************** :***:**** **::***.*****.*:**:*:*: *.**.**::***:*.:**:*:* * :** **:**:*. * . *::*..**: :*:* . : **:** *: . * .*: .:. .* : :.* :: * . * :* ", "identical_positions": 252, "similar_positions": 154, "identity": "37.67%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010426-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q16526-1", "uniprot_id": "CRY1_HUMAN", "id": "Q16526-1", "name": "Cryptochrome-1", "aln": "MGVNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLISKMEPLEIPVETITSEVIEKCTTPLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLER---KAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQLSRYRGLGLLASVPSN------PNGNGGFMG--------YSAENIPGCS------SSGSCSQGSGILHYAHGDSQQTHLLKQ----------GRSSMGTGLSGGKRPSQEED--------TQSIGPKVQRQSTN-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AXA7-1", "uniprot_id": "A0A8M3AXA7_DANRE", "id": "A0A8M3AXA7-1", "name": "", "aln": "MSVNSVHWFRKGLRLHDNPALLEALNGADTLRCVYFLDPWFAGASNLGVNRWRFLLQSLEDLDASLRKLNSCLFVIRGQPADIFPRLFKEWKVSRLTFEFDSEPFGKERDAAIKKLACEAGVEVIVKISHTLYDLDRIIELNGGQSPLTYKRFQTLVSSMEPPDPPLASPDRGMMGKCVTPISENHRDKYGVPLLEELGFDTEGLAPAVWPGGESEALKRMERHLGPDSTVAWQENFERPKMNASPLMASPLGLSPYLRFGCLSCRLFYCKLTQLYKKVKKNMNPSISLYDKILWREFFYTAATNNPRFDRMEGNPICIRIPWDRNAEALAKWAEAKTGFPWIDAIMMQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSVNAGSWLCHSCSSFFQQFFHCYCPVGFGRRIDPNGDFIRRYLPVLRDFPAKYIYDPWNAPHDVQLAAKCVIGVDYPKPMVNHAEASRLNIERMRQIYQQLSRYRGLSLLATVPSNHIEDAAANVNRGAMAPPTRRKTRNDASSYTGVRREQPGPSGAKHRHRHSLSHRPSPYATQSELTDHNHEFAVPQQPGRVSWPNVGGTGKKEGEAEHNCCRGDNGPSSSALKAQQQDNEKRREDAEGVAFST", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.**:**************** *.::****:****:*******:**:*:********.******.****** **********:********::::*::*:***************** ********:*********:********.**********:*.*** : *: : :: **.**:*::* :***** ********:**:.*******:***.*:**** ** *****:***..*:*** ***************** ***:******** .*.:***.::*****************:*******::****:*.********.:********** **********************************************:*****: ********************* *****:*********.*************..:* .***:***:*******************:************.***:**** .* * * *. .*.. .* *... : .: * . : *:.* .: ** * . . **: .: *. ..* . *.*:*..: ", "identical_positions": 428, "similar_positions": 104, "identity": "66.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010426-8", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q0E8P0-1", "uniprot_id": "Q0E8P0_DROME", "id": "Q0E8P0-1", "name": "", "aln": "MDSQRSTLVHWFRKGLRLHDNPALSHIFTAANAAPGKYFVRPIFILDPGILDWMQVGANRWRFLQQTLEDLDNQLRKLNSRLFVVRGKPAEVFPRIFKSWRVEMLTFETDIEPYSVTRDAAVQKLAKAEGVRVETHCSHTIYNPELVIAKNLGKAPITYQKFLGIVEQLKVP-KVLGVP--EKLKNMPTPPKDEVEQKDSAAYDCPTMKQLVKRPEELGPNKFPGGETEALRRMEESLKDEIWVARFEKPNTAPNSLEPSTTVLSPYLKFGCLSARLFNQKLKEIIKRQPKHSQPPVSLIGQLMWREFYYTVAAAEPNFDRMLGNVYCMQIPWQEHPDHLEAWTHGRTGYPFIDAIMRQLRQEGWIHHLARHAVACFLTRGDLWISWEEGQRVFEQLLLDQDWALNAGNWMWLSASAFFHQYFRVYSPVAFGKKTDPQGHYIRKYVPELSKYPAGCIYEPWKASLVDQRAYGCVLGTDYPHRIVKHEVVHKENIKRMGAAYKVNREVRTGKEEESSFEEKSETSTSGKRKVRRATGSAPKRKR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "F1QHM9-1", "uniprot_id": "F1QHM9_DANRE", "id": "F1QHM9-1", "name": "", "aln": "---MSHNTIHWFRKGLRLHDNPALIAALKDCR------HIYPLFLLDPWFPKNTRIGINRWRFLIEALKDLDSSLKKLNSRLFVVRGSPTEVLPKLFKQWKITRLTFEVDTEPYSQSRDKEVMKLAKEYGVEVTPKISHTLYNIDRIIDENNGKTPMTYIRLQSVVKAMGHPKKPIPAPTNEDMRGVSTPLSDDHEEK----FGIPTLEDLGLDTSSLGPHLFPGGEQEALRRLDEHMERTNWVCKFEKPKTSPNSLIPSTTVLSPYVRFGCLSARTFWWRLADVYRG-KTHSDPPVSLHGQLLWREFFYTTAVGIPNFNKMEGNSACVQVDWDNNPEHLAAWREARTGFPFIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGQKVFEELLLDSDWSLNAGNWQWLSASTFFHQYFRVYSPIAFGKKTDKHGDYIKKYLPVLKKFSTEYIYEPWKAPRSVQERAGCIVGKDYPRPIVDHEVVHKKNILRMKAAYAK----RSPEDKTINKGEKRKASPSIKEMFQK------KAKR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*************** :. .. .: *:*:*** : . ::* ****** ::*:***..*:***********.*:**:*::**.*:: ****.* **** :** * **** **.* .: ***:** : :* :* **:*:** :: .:*: : * * : .* *.::.:.** .*: *:* :. **:::* ...***: ***** *****::* :: **.:****:*:**** *********::******* * :* :: : .**:***** ***:****:**.*.. ***::* ** *:*: *:::*:** ** ..***:******* *********************************:***:****.**:****** *****:***********:******* :*.**:**:* *.*:.: *******. *. **::*.***: **.******:** ** *** *: ::: . ** ::*.* *. .:: * **", "identical_positions": 295, "similar_positions": 131, "identity": "54.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010430-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N1B4-1", "uniprot_id": "VPS52_HUMAN", "id": "Q8N1B4-1", "name": "Vacuolar protein sorting-associated protein 52 homolog", "aln": "MAAAATMAAAARELVLRAGTSDMEEEEGP-LAGGPGLQEPLQLGELDITSDEFILDEVDVHIQANLEDELVKEALKTGVDLRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQITACDAVLERMEQMLGAFQSDLSSISSEIRTLQEQSGAMNIRLRNRQAVRGKLGELVDGLVVPSALVTAILEAPVTEPRFLEQLQELDAKAAAVREQEARGTAACADVRGVLDRLRVKAVTKIREFILQKIYSFRKPMTNYQIPQTALLKYRFFYQFLLGNERATAKEIRDEYVETLSKIYLSYYRSYLGRLMKVQYEEVAEKDDLMGVEDTAKKGFFSKPSLRSRNTIFTLGTRGSVISPTELEAPILVPHTAQRGEQRYPFEALFRSQHYALLDNSCREYLFICEFFVVSGPAAHDLFHAVMGRTLSMTLKHLDSYLADCYDAIAVFLCIHIVLRFRNIAAKRDVPALDRYWEQVLALLWPRFELILEMNVQSVRSTDPQRLGGLDTRPHYITRRYAEFSSALVSINQTIPNERTMQLLGQLQVEVENFVLRVAAEFSSRKEQLVFLINNYDMMLGVLMERAADDSKEVESFQQLLNARTQEFIEELLSPPFGGLVAFVKEAEALIERGQAERLRGEEARVTQLIRGFGSSWKSSVESLSQDVMRSFTNFRNGTSIIQGALTQLIQLYHRFHRVLSQPQLRALPARAELINIHHLMVELKKHKPNF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IY52-1", "uniprot_id": "A0A0R4IY52_DANRE", "id": "A0A0R4IY52-1", "name": "Vacuolar protein sorting-associated protein 52 homolog", "aln": "MAEALIGGAVHINTSADSVTGAMACITLHDEKSNFDVIPPLNFGDLDITTDELILDEVDIHIQANLEDDLVKEALKTGVDLRQYSRQVETELQQIEQASIKDYIKESQNIASLHNQITACDSILERMEGMLSSFQSDLSSISSEIQTLQQQSVSMNMRLKNRQAVRSQLSQLVDELVVPSTMISVILDSPVTEQEFLEQLHELNNKINFAKELSFRETLACSDIQDIVDRLKIKAVTKIREFILQKIYSFRKPMTNYQIPQNTLLKYRFFYQFLLANERTVAKEIRDEYVDTMSKIYLSYFKSYSGRLLKVQYEDVADKDDLMGVEDTAKKGFFSKPSLKSRNTIFTLGQRGAILSPAELEGPILIPHAAQRGDSRYPYETLFRSQHYALLDNGCREFLFLSDFFMVAGNSALDLFNSIMGKTLSIFLKNLSTYLSDCYDSIAVFLCIHIILRFRAIVAKRNIPALDKYLEAVLELLWPRFELILEMNIQSIRNTDPQKLGVLDTRPHYITRRYAEFSSAIVSINQTFPNERTNTLLGQLQIEVENFVLKMAAEFPSRRDQLIFLINNYDMMLSVLMERAADDSKEVESFQQLLLARTQEFIEEILSPPFGGMIAFVKESEALMEKGQLDKLKNDEARITQLVRGFSGTWKQSVEALSQDVMRSFTNFKNGTSIIQGALTQLIQYYHGFHKVLSQPTFRSLAVRSELINLHHLMVEVKKHKPNF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * .*. : : *. * .. .: **::*:****:**:******:********:*************:**:*** ******* **:***:**:*************::***** **.:************:***:** :**:**:******.:*.:*** *****::::.**::**** .*****:**: * .:* . * * **:*::.::***::****************************.:************.***:.*********:*:*******::** ***:*****:**:*********************:********* **:::**:***.***:**:****:.***:*:************.***:**:.:**:*:* :* ***:::**:***: **:*.:**:****:*********:**** *.***::****:* * ** *************:**:*.****:** ******************:******:***** ******:*******::****.**::**:**********.******************** *********:*******::*****:***:*:** ::*:.:***:***:***..:**.***:************:*************** ** **:***** :*:*..*:****:******:*******", "identical_positions": 526, "similar_positions": 143, "identity": "72.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010430-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70489-1", "uniprot_id": "PPT2_RAT", "id": "O70489-1", "name": "Lysosomal thioesterase PPT2", "aln": "MPGLWRQRLPSAWALLLLPFLPLLLPAAPAPHRGSYKPVIVVHGLFDSSYSFRHLLDYINETHPGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMEKAPEGVHLICYSQGGLVCRALLSVMDEHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRICYSPWGQEFSICNYWHDPHHDDLYLNASSFLALINGERDHPNATAWRKNFLRVGRLVLIGGPDDGVITPWQSSFFGFYDANETVLEMEEQPVYLRDSFGLKTLLARGAIVRCPMAGVSHTTWHSNRTLYDA-------CIEPWLS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35448-1", "uniprot_id": "PPT2_MOUSE", "id": "O35448-1", "name": "Lysosomal thioesterase PPT2", "aln": "MPGLWRQRLPSAWALLLLPFLPLLMPAAPAAHRGSYKPVIVVHGLFDSSYSFRHLLDYINETHTGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMEKAPEGVHLICYSQGGLVCRALLSVMDNHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRVCYSPWGQEFSICNYWHDPHHDDLYLNASSFLALINGERDHPNATAWRKNFLRVGRLVLIGGPDDGVITPWQSSFFGFYDANETVLEMEEQPVYLRDSFGLKTLLARGAIVRCPMAGISHTTWHSNRTLYDT-------CIEPWLS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UMR5-1", "uniprot_id": "PPT2_HUMAN", "id": "Q9UMR5-1", "name": "Lysosomal thioesterase PPT2", "aln": "MLGLCGQRLPAAWVLLLLPFLPLLLLAAPAPHRASYKPVIVVHGLFDSSYSFRHLLEYINETHPGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMAKAPQGVHLICYSQGGLVCRALLSVMDDHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRICYSPWGQEFSICNYWHDPHHDDLYLNASSFLALINGERDHPNATVWRKNFLRVGHLVLIGGPDDGVITPWQSSFFGFYDANETVLEMEEQLVYLRDSFGLKTLLARGAIVRCPMAGISHTAWHSNRTLYET-------CIEPWLS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HX37-1", "uniprot_id": "A0AC58HX37_DANRE", "id": "A0AC58HX37-1", "name": "palmitoyl-CoA hydrolase", "aln": "MKGACVWTLVSVCVFCVC---------------VAYKPVIVVHGLFDSSADFVHLHRFINLSHPGTNVTVLDLFDRSASLQPLWKQVEGFTEAIYPIMQNAADGVHLICYSQGGLVCRGILSTLPDHNVHSFISLSAPQAGQYGDTDYLKYLFPQFVKSNLFHVCYTAVGQKISICNYWNDPHHRDMYINSSDYLALLNNERPNPNSTAWKQNFLRIKKLVLIGGPDDGVITPWQSSQFGFYDDNETVVEMKNQKVFLMDLFGLKTLSARGDLALCSVEGVAHIFWHSNETYFSALHQNRHFCYSDSASMENP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKH6-1", "uniprot_id": "PPT2_DROME", "id": "Q9VKH6-1", "name": "Lysosomal thioesterase PPT2 homolog", "aln": "----MRLRLQVLVALLTCSSISVS---------LAYKPVVILHGILSGAESMASLVREIEEFHPGTIVYNCDKFNGWYSLENAWRQVDQVRDYLNEVGKLHPEGIIVLGYSQGGLLARAAIQSLPEHNVKTFISLSSPQAGQYG-TSFLHLIFPDLAAKTAFELFYSRVGQHTSVGGYWNDPQRQDLYLKYSEFLPLINNEKKTSNSTSFKMGMVRLNKLVMIGGPNDDVITPWQSSHFGYFDENMDVIPFIRRPIFTSDSIGIRTLQEAGKLIIVVKPHVHHLAWHTRRDVIHE-------VIFPYLD----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: :****:::**::..: .: * *: *.** * * *: **. *.**: . : : : .:*: :: ******:.*. :. : :***.:*****:** **** *.:*: :** .. :.: *: **. *: .**:**:: *:*:: *.:*.*:*.*: .*:* :: .::*: :**:****:*.******** **::* * *: : .: :: * :*::** * : : * **:.. . ", "identical_positions": 92, "similar_positions": 92, "identity": "29.39%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010430-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q15477-1", "uniprot_id": "SKI2_HUMAN", "id": "Q15477-1", "name": "Superkiller complex protein 2", "aln": "MMETERLVLPPPDPLDLPLRAVELGCTGHWELL------NLPGAPESSLPHGLPPCAPDLQQEAEQLFLSSPAWLPLHGVEHSARKWQRKT----DPWSLLAVLGAPVPSDLQAQRHPTTGQILGYKEVLLENTNLSATTSLSLRRPPGPASQSLWGNPTQYPFWPGGMDEPTITDLNTREEAEEEIDFEKDLLTIPPGFKKGMDFAPKDCPTPAPGLLSLSCMLEPLDLGGGDEDENEAVGQPGGPRGDTVSASPCSAPLARASSLEDLVLKEASTAVSTPEAPEPPSQEQ------WAIPVDATSPVGDFYRLIPQPAFQWAFEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVWEEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYLFTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQP-THQGGPAQDRGVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKPSQLQSQFRLTYTMILNLLRVDALRVEDMMKRSFSEFPSRKDSKAHEQALAELTKRLGALEEPDMTGQLVDLPEYYSWGEELTETQHMIQRRIMESVNGLKSLSAGRVVVVKNQEHHNALGVILQVSSNSTSRVFTTLVLCDKPLSQD-PQDRGPATAEVPYPDDLVGFKLFLPEGPCDHTVVKLQPGDMAAITTKVLRVNGEKILEDFSKRQQPKFKKDPPLAAVTTAVQELLRLAQAHPAGPPTLDPVNDLQLKDMSVVEGGLRARKLEELIQGAQCVHSPRFPAQYLKLRERMQIQKEMERLRFLLSDQSLLLLPEYHQRVEVLRTLGYVDEAGTVKLAGRVACAMSSHELLLTELMFDNALSTLRPEEIAALLSGLVCQSPGDAGDQLPNTLKQGIERVRAVAKRIGEVQVACGLNQTVEEFVGELNFGLVEVVYEWARGMPFSELAGLSGTPEGLVVRCIQRLAEMCRSLRGAARLVGEPVLGAKMETAATLLRRDIVFAASLYTQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NZR5-1", "uniprot_id": "SKI2_MOUSE", "id": "Q6NZR5-1", "name": "Superkiller complex protein 2", "aln": "MMETERLVLPPLDPLNLPLRALEVGCTGRWELL------NVPGPPESTLPHGLPPCAPDLCQEAEQLFLSSPAWLPLHGVEHSARKWQRKT----DPWSLLAAVETPVPSDLQAQRHPTTGHILGYKEVLLENTNLSATTSLSLRRPPGPASQSLWGNPTQYPFWPGGMDEPSITDLHTREEAEEEIDFEKDLLTVPPGFKKGVDFAPKDHPAPVPGLLSLSRLLEPLDLSGGDEDEGEAAG---GPRGDNASPSPSGTPLVRASSLEDLVLKEAATVVSTPEPPKPPPQEQ------WAVPVDVTSPVGDFYRLIPQPAFQWAFEPDVFQKQAILHLEQHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDAERGVVWEEVLIMLPEHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVARPVPLEHYLFTGNSPKTQGELFLLLDSRGAFHTQGYYAAVEAKKERMSKHAQTFGAKQP-THQGGPAQDRGVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQLPQVLHMSELLRRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKPSQLQSQFRLTYTMILNLLRVDALRVEDMMKRSFSEFPSRKDSKAHEQALADLTKRLGALEEPDVTGQLADLPEYYSWAEELTETQNMIQRRIMESVNGLKSLSVGRVVVVKNEEHHNALGVILQVSSNSTSRVFTTLVLCDKPVVSDNPRDKGPATPDVPHPDDLIGFKLFLPEGPCEHTVAKLQPGDVAAISTKVLRVNGEKISEDFSKRQQPKFRKDPPLAAVTTAVQELLRLAQSYPAGPPTLDPINDLQLKDVAVVEGGLRARKLEELIRGAQCVHSPRFPAQYVKLRERMQIQKEMERLRFLLSDQSLLLLPEYHQRVEVLRTLGYVDEAGTVKLAGRVACAMSSHELLLTELMFDNALSALRPEEIAALLSGLVCQSPGDPGDQLPSTLKQGVERVKAVAKRIGEVQVACGLNQTVEEFVGELNFGLVEVVYEWARGMPFSELAGLSGTPEGLVVRCIQRLAEMCRSLRGAARLVGEPVLGAKMETAATLLRRDIVFAASLYTQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58HYF7-1", "uniprot_id": "A0AC58HYF7_DANRE", "id": "A0AC58HYF7-1", "name": "", "aln": "--MSILTDLPPVGPDDLPLSLLEMGCSGRFELITHTLPKNKPLPPHSTLPHGLPPTCLDLKTEVEKRFLRDPAWLPVHDVDDAFNKFLKISKREKEVDSLLHCSLSQLHSGLSVVRDPTTGMLLDFTEVLLEDTGLSAKNSLSLQRQPGPPSESLRGSNTNYPFLPAGMEELTLEQIKNKSELEEDIDFEKDLMTVPPGLKAGMDFSDKEARNTKSEVNLLSLLSTFDDVLDAPPEDKEGVS-----QKEEIVKLPRTNSLEDLGIKDSGSSQPQGNTGSLTEQKKKNLEEEKGDNKKWAIPVDISSPCADFYKRIPDPAFKYPFELDVFQKQAILRLEAHDSVFVAAHTSAGKTVVAEYAIALSQKHMTRTIYTSPIKALSNQKFRDFKNTFGDVGLLTGDVQLNPEGSCLIMTTEILRSMLYNGSEVIRDLEWVIFDEVHYINDAERGVVWEEVLIMLPEHVSIILLSATVPNAVEFSEWIGRIKKRHIYVISTIKRPVPLEHYLYTGNSTKTQKELFMLLDATGNFLTKGYYAAVEAKKERTSKHAQSFGTKNVSQHNTTASQDRAVWQTLLNYLSQRQQTPVVAFTFSRTRCDENARSLTSLDLTTSIEKSEIHSFLQKSLTRLRGGDRQLPQILLMRDLLKRGIGVHHSGILPILKEVIEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSIRKHDGTGFRNLLPGEYIQMAGRAGRRGLDATGTVIILCKAGVHDMGELHSMMLGKPTVLHSQFRLTYTMILNLLRVEALRVTDMMKRSFSEN--HRDTQAHEKRISELRNTLSSLPPLDTEGQLSDLLSYYHTITELHITTQSLQQAVLESVNGLKALSVGRVVIVNNSQHHNSLGVILQVSSDAVNRTFTALIICEKGNEEAASDEQ---SNKVALP--IYSKTLFIPEGPCSHTVQKLKLQDISAITTKALKVIPERIIDNYNKRLQPRFRLDPPGQAISTATQELLRLAEANMGGMTVLDPVNDLHLKGVDVVEGVMRQRVLQDSLKDFHCIHSPTFSEQFTRVQERMSVQEELDKLLFLVSDQSLTLLPEYHQRIKVLEALQYVDSSGAVQLKGRVACQISSHELLLTELLFENTLSPLAPEESAALLSCLVFTQNTQIEPHITNTLQEGINQVLAVAQRIGDLQRDCGIAQTAEDFVAQFKFGLTEVVYCWARGMPFAEIAQLTDVQEGTIVRCIQRLDEVLKEVRQAARIVGDSVLGSKMERASLAIRRDIVFTASLYTH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *** .* :*** :*:**:*::**: * * .*.*:******* . ** *.*: ** .*****:*.*:.: .*: : : : *** : : *.*.. *.**** :*.:.*****:*.***..****:* ***.*:** *. *:*** *.**:* :: :::.:.* **:*******:*:***:* *:**: *: . . : ** : *: .. :: *... : : * .* . :. : ... * .* : :*: **:*** :** .***: **:***::.** *********:** ************************:************************:***************:**.***************.**:******************.**************:**************:**::****:*:*:******: *********:****.*** ***:***: * * *:************ *****:**:*: *: .:***.*: :** * * * ***.***** ****:* .********* ****** ***:.*:****.******:* * :**.**:*************::*********************************:*****: **:******:************.*****:***. * :*.:** **:***: *:****************:**** ********* ::*::***: :::* : *.:* * *** ** .** ** * : :*: ::*******:**.****:*:*.:***:*********::..*.**:*::*:* . . :: : .*. * : . .**:*****.*** **: *::**:**.*:* *:* :::.** **:*: *** *::**.*******:: .* ..***:***:**.: **** :* * *:: ::. :*:*** *. *: :::***.:*:*:::* **:***** ********::**.:* ***.:*:*:* ***** :**********:*:*:**.* *** ***** ** . : ::..**::*:::* ***:***::* **: **.*:**.:::***.**** *******:*:* *:.. ** :******* *: :.:* ***:**:.***:*** *: :******:*****:", "identical_positions": 741, "similar_positions": 296, "identity": "58.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010501-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23511-1", "uniprot_id": "NFYA_HUMAN", "id": "P23511-1", "name": "Nuclear transcription factor Y subunit alpha", "aln": "----------------------MEQYTANSNSSTEQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVS----GGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPG-AGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKEKDSPHMQDPNQADEEAMTQIIRVS----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23708-1", "uniprot_id": "NFYA_MOUSE", "id": "P23708-1", "name": "Nuclear transcription factor Y subunit alpha", "aln": "----------------------MEQYTTNSNSSTEQIVVQAGQIQQQQ-GGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVS----GGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPG-AGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKEKDSPHMQDPNQADEEAMTQIIRVS----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18576-1", "uniprot_id": "NFYA_RAT", "id": "P18576-1", "name": "Nuclear transcription factor Y subunit alpha", "aln": "----------------------MEQYTANSNSSTEQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVS----GGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQ------GMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPG-AGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKEKDSPHMQDPNQADEEAMTQIIRVS----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3B723-1", "uniprot_id": "A0A8M3B723_DANRE", "id": "A0A8M3B723-1", "name": "Nuclear transcription factor Y subunit", "aln": "----------------------MEQYTTTTTTSGEQIVVQASGGQIQQQGTVTAVQLQTEPQVGQTAAQ--QVLQVVQGQPLMVQVS----GGQLITSSGQPIMVQAMTGGQGQTIMQVPVSGTQGLQQIQLVQPGQIQLPGGQTLQLQGQQGQTQQIIIQQPQTAVTAGQNQGQQQITVQGQQVAQTAEGQTIVYQPVNADGTILQQ------GMITIPAASLAGAQLVSAGSNTNTTNTGQGTVTVTLPMAGNMVNAGGMVMMVPGGSNSVPTMQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGDGGRFFSPKEKEEMALQAIKVSEGLELSSHWPATSAPPLG----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P06774-1", "uniprot_id": "HAP2_YEAST", "id": "P06774-1", "name": "Transcriptional activator HAP2", "aln": "--------------------------------------MSADETDAKFHPLETDLQSDTAAATSTAAASRSPSLQEKPIEMP-----------LDMGKAPSPRGEDQRVTNEEDLFLFNRLRASQNRVMDSLEPQQQSQYTSSSVSTMEPSADFTSFSAVTTLPPPPHQ-------------------------------------------------------QQQQQ-----------QQQQQQQQLVVQAQYTQNQPNLQSDVLG----------------TAIAEQPFYVNAKQYYRILKRRYARAKLEEKLRISRERKPYLHESRHKHAMRRPRGEGGRFLTAAEIKAMKSKKSGASDDPDDSHEDKKITTKIIQE-----QPHATSTAAAADKKT-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VSY9-1", "uniprot_id": "Q9VSY9_DROME", "id": "Q9VSY9-1", "name": "Nuclear transcription factor Y subunit", "aln": "MENHFSATSRPSATPRMCTTASAVGAAASAAAAAGNNNNNSNSSSNNNATTGNNLSVSTAAGGATNAAATAQPIQVIPMPMLPTGAAQIIIGQQPQGQATATGLQPQLIPLQANQIMLQAAQQQPQMQVMQLPDGQTIFYQTPTIAALDPNAAANAAAAMAAQPTPHYLNINGQLVQINPAPSANQAAPTAGQQIIMVPQTAMAAVNAAAANAGVGAGVGTVVTQQQQQQHQQVQSQTQNQQQQQQQQTVAAVAASAAVNNISADVSTSTTGTNTNSEDESS-KGEADEEPLYVNAKQYKRILIRRQARAKLES--RIPKERCKYLHESRHRHAMNRARGEGGRFHSAQEKGDQDSSGPEGGSMPMASSGGVTLSRGTARAPPKLIAPHQTPSITITAIKSE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:. . : . :. .* . . :. :* .: . : : :: .* :: . . : .. * * : . .: * *:*:******* *** ** ****** :*.:** *******:*** * **:**** :. * . .. : ", "identical_positions": 47, "similar_positions": 46, "identity": "11.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010501-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48634-1", "uniprot_id": "PRC2A_HUMAN", "id": "P48634-1", "name": "Protein PRRC2A", "aln": "MSDRSGPTAKGKDGK-KYSSLNLFDTYKGKSLEIQKPAVAPRHGLQSLGKVAIARRMPPPANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDE-----------------LEGPD--SKLHHGHDPRGG--------------LQPSGPPQFPPYRGMMPPF--MYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAG---PRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPE---------ADGKKGNSPNSEP---------PTPKTAWAETS----------------RP--------PETEPGP-------------------PAPKPPLPPPHRGPAGNWGPPGDYPDRGGPP-----CKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGS-FEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDG---------IGPTRQPPS--QGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVP--APQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPP-LDFYPPGVHPSGLVPRERSDSGGSSSEPFDR--HAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDD---KGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVLPSPARPFPASLGRAELHPVELKPFQDYQKLSSNLGGPGSSRTPPTGRSFSGLNSRLKATPSTYSGVFRTQRVDLYQQASPPDALRWIPKPWERTGPPPREGPSRRAEEPG-SRGDKEPGLPPPR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8PXX5-1", "uniprot_id": "A0A2R8PXX5_DANRE", "id": "A0A2R8PXX5-1", "name": "", "aln": "MSERSGQTAKGKDGKTKYASLNLFDTYKGKSLEAQKPVVAPRHGLQSLGKVASTRRMPPPANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQADPKSTDVLSAAQPESQQPVASQTSAPSIPRTPPAQEPPTPALAVGPRSWAPASVTHGAQGDGGKGSNQPSPFSREEFPTLQAAGDQDRAGKEQATADQWYGPGPSLRPQNVTSWRDGGGRALAPTLAGEAVAEGGAGGVILMEGAAGAPPIQQQNASSHGPPRTPPTSNPALPLPQPTIGPQFQAYRGIMPPFVSMYPPYLPFPPPYGPQGPYRYPPPNEAPRFSRNQGGIGPDGRPPGGPRGEVVKRPSILKQDDLKELDELDHDGDEGWAGAQEEIDYSAKLKFSDDEGEDDGEEERGENKNGTRESREQQRSQDGPVPVSRSRASDSGGDSRRTPPSSTEDGSVSPSSKPGWAEEGGSSWNSQANAGSYQGPRPGLGGTREQPSPPPGPLLGQGPHSYYRQDRPSNQSPIPGPILAPQKPSSAHAQQQAGTVPGGPTPPPSNTLHPQQQGEDEDETWRQRRKQSSTEISAAVERARRRREEEERRMQEERRAACAEKLKRLDEKQ----QQQTIKPSSPSDAPAN-SPSPSLSAHASSPNVSQPS---SPCVDTEEPPLLSAQGSGATLGLTNNNRQRAGSNSSHDSNNESQQVLQPQATQHPQSQDVPGPGDIKEEHVVGGPHIRSTRVGDDSVKVVECVGVTGRQGSGPSGQGFSKYQKSLPPRFQRQQQEQLLKQQQQWQQQQQQHNQVAAQNQLQSQPQ-NQQGPAPGTAPQSGPKQPTLYPPGSMGRPPPLP-MNFDPRWMMMP-YMDPRMMQGRPPPMDYYPPSMHPSGMMNRERSDSGGSGSDPFDRQQHAGPPHSHRGTPPMDPKLAWGPDVFPGG-TEGRGLSSPLRQKAVEEEEAGKGQRSDTPPVR--------------------------MREGG------------TASVQQP-------------------GVAPSSPSGSSNQTPPP--------------------------------------------------------------------LGIQVGGAGHHAHHQP--------------------------------FLDGRGGYSSYPDN--GSRMGSHLQQRANSGGTLHGFGHQEGSQPNQIWG--TPHPHYDRSDHSALESNSHHQHHGPPSHAPHFSLHPHKQENGREREKMVEPKKNDPSPPLHQPSLSSSCSSSSSS--------SSAREDGSGK-------------QSLHNQVP-------------------PLHEHDTGSTHASG-----------RKQDKTGNAHNQPPQHSGQQHHPRANPRNREHKT-----ETHWGPRPGSSSVSGSSTHNRKTGSGIIAITEPSGNQGAENKSFNQSDGITVKRAGPIKRP-----VLKEIKREGGEGGGEK-----TTGGSGKDKEQDAS-QTTTKQEPATGNQVILAPSGKDDAVSSNKPRTGGKERGNTGGSGKGSKNGESSMQNSGYSASQSRREREHSPERGSTTYHSSSSRGSRSNRGRGEFYGRGRGYRGTYVGSAGGGNRGKAGGRNS-RDYRPAANSGYHHP------SSNQDYKREASSGSGRHGTSQ------PNPGRARNRSETRSEGSEYEEVPKRRRQRGSETGSESAGSDLAHSDKEDRKLN----TKAGTVGENPTTGPSSSASVRNTQTRVFTPRGVPSRRGRGGGGAGGGLHRS-----------GGGAGVSGGQRPGPGSSSHGWSAKSANVRKPQTSSQPPPAKDLSRGVNVDKKKPAE---------QNQPQSQSANPTTTVASVPTTIQQGSTENGN-----VGAPMSSTN------------------APSNPAGAPTQS--------LPLPAPDGRNFPNRGFE---RPPRRRRHGRSQHQQDKP------PRFRRLKQERENAARINGSSGLIEVIAAQQQRTAPLLQNSLQQANSTPNVPDAVVANANHSVSTTP---------------------NSNNNSSNLAGGNQN------FNSHHHHHYQGNSQSHPQHHHNHNPAGGAKSPDVSNQNSDQANEEWETASESSDFTEFREREGGGG------GKSYSSHHHHHHHHHHPPGRGGGGGGGGDREMTAKELASGKRS------------FSSQRPGMERQNRRVNAGGGGGGKGQR-GPPGTGGPVGGAGNGGGNRGERRGNWPSPKNRK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*** ******** **:************** ***.************** :***************************************:****:*. :* **** ****.*.. *: *** ** :. * :*** *******:****:.*. * ****************:*.**: :*:* ********** *:*******. :**. . ::: : . * **: *** .***:**** *********************.*: ..**.* * * * * * * ******:*:***:*:**::.*:*****:**:**: ******:*. *.:** .*.:..::.: ::*. : *... *:* .: * *:.*..*** . ** *.. *** * * * *.* : ..* .* *. ** *****:*********:*** ********************************** :: . :*::*. **:. :*.*::. . .:* .. *: :* .:.***. .. * .* *:: :*..*: .:.. * .* .* *..:. * :: . *::... * :* * : * .* *:.************************ * **:*:..... * ** *..* ***: * *. **::*****:* *********:* *:***::***** :*:***.:****:: *********.*:**** ** . .*****:****** ***.. :* * *:***** * *:: ** **:**** :.* * .*.:* * * *: **..* *** * * * * . * * *** .:* .. *:* .. . * *. :* * .:* * :...: : *::. : .. ::: . *.: . .* * .:* :* : *.** ** :.: :: .. .* * *.*: :** : * ** *.::... *::. .: :::**:. ::. . .*. * *. : **. . ::*: :.: .* :... .: *.: . * :: .:*..:* :* * : * . * : ** *** : *. .:: :* * :: :.*.*. .* . .* . . *.... ** *. *.*:*.*.. .* :* . ...: .* *:: .: :** . : . * * :.** * *.* :: :. * . : *. **: .::. .. * **.: * * : *:*. :.* : *.:* : . : .*..*.: *. . *. .: *. .. : *** . :. : . *. :. .* . .*. : * ** *.: * **.** :. . . .:.. :**** . . :: :::* *. :. ...* . ..:* *::::.. ** .:.: : ** .*.* .** :* *:..*:.: . * *. : * : ..* :* * *: *.:. : ... ..: : .. :*: * **.. ::* . * . *. :* *: *: * *.*. ::: :** :. . ** . .* :* . * : . * ... . * . . *:: . : .:.: .. ** *..* .: . ** .* * :** .: :* :* :* *** ** * : * .**::. . *.*: ", "identical_positions": 681, "similar_positions": 529, "identity": "29.79%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010504-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50569-1", "uniprot_id": "STF1_RAT", "id": "P50569-1", "name": "Steroidogenic factor 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDYSYDED------------------------------------------------------------------------------------------------------------------------LDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQ--KKAQIRANGFKLETGPPMGVPPPPP-------------------------PPPDYMLPPSLHAPEPKALVSGPPSGPLGDFGAPSLPMAVPGPHGPLAGYLYPAFSN--------------------------------------RTIKSEYPEPYASPPQQPGPPYSYPEPFSGG--------PNVPELILQLLQLEPEEDQVRARIVGCLQEPAKSRP--DQPAPFSLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVLDHIYRQVQYGKEDSILLVTGQEVELSTVAVQAGSLLHSLVLRAQELVLQLHALQLDRQEFVCLKFLILFSLDVKFLNNHSLVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P33242-1", "uniprot_id": "STF1_MOUSE", "id": "P33242-1", "name": "Steroidogenic factor 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDYSYDED------------------------------------------------------------------------------------------------------------------------LDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQ--KKAQIRANGFKLETGPPMGVPPPPP-------------------------PPPDYMLPPSLHAPEPKALVSGPPSGPLGDFGAPSLPMAVPGPHGPLAGYLYPAFSN--------------------------------------RTIKSEYPEPYASPPQQPGPPYSYPEPFSGG--------PNVPELILQLLQLEPEEDQVRARIVGCLQEPAKSRS--DQPAPFSLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVLDHIYRQVQYGKEDSILLVTGQEVELSTVAVQAGSLLHSLVLRAQELVLQLHALQLDRQEFVCLKFLILFSLDVKFLNNHSLVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13285-1", "uniprot_id": "STF1_HUMAN", "id": "Q13285-1", "name": "Steroidogenic factor 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDYSYDED------------------------------------------------------------------------------------------------------------------------LDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQ--KKAQIRANGFKLETGPPMGVPPPPP-------------------------PAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPG--------------------------------------RAIKSEYPEPYASPPQ-PGLPYGYPEPFSGG--------PNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRP--DQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QJG0-1", "uniprot_id": "F1QJG0_DANRE", "id": "F1QJG0-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDFRADED------------------------------------------------------------------------------------------------------------------------LEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCTQNQDCGIDKTQRKRCPFCRFQKCLSVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQ--KRALIRASGFKLEANG-------------------------------------------TLLSGQTEFSSVGLQS-PY-DCPPPALGVALQNYGSFPAQYQYTAPSLP-------------------------------------KSIKAEYPDAYSSSPD-STLGYSYADGCLSASPHSVPINPALPPLVLELQSCDPDEEQVRGKICAYLHQEQSGRGKLEKSRPFSLLCVMADQTLFSIVEWARSCVFFKELKVGDQMRLLHNCWSELLLLDHICRQVHHGRDGSLLLITGQEVELS-AVLDAGPPLSSMVERGQDLSRRLQLLQVDSREMACLKFLILFNPNVKLLENPQFVESVQEQVNGALLEYTLFSYPQCVERFSQLILRLPELRSLSAEAEDFLCYKHLCGEVPCNNLLIEMLHAKRSSAQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P33244-1", "uniprot_id": "FTZF1_DROME", "id": "P33244-1", "name": "Nuclear hormone receptor FTZ-F1", "aln": "MDTFNVPMLAESSNTNYATEATSNHHHLQHQHQQQHSHQQQQQQQLLMPHHHKDQMLAAGSSPMLPFYSHLQLQQKDATATIGPAAAAAAVEAATTSANADNFSSLQTIDASQLDGGISLSGLCDRFFVASPNPHSNSNMTLMGTATAATTTTTNNNNNNNTNNNNNNNVEAKTVRPSNGNSVIIESVTMPSFANILFPTHRSANECIDPALLQKNPQNPNGNNSSIIVPPVEYHQLKPLEVNSSTSVSTSNFLSSTTAQLLDFEVQVGKDDGHISTTTTTGPGSGSASGSGSGSGSGSGSIARTIGTATPTTTTSMSNTANPTRSSLHSIEELAASSCAPRAASPNSNHTSSASTTPQQQQQQQHHMQSGNHSGSNLSSDDESMSEDEFGLEIDDNGGYQDTTSSHSQQSGGGGGGGGGNLLNGSSGGSSAGGGYMLLPQAASSSGNNGNPNAGHMSSGSVGNGSGGAGNGGAGGNSGPGNPMGGTSATPGHGGEVIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRNSMGPDIKPTPISPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASTGGVIATPMNAGTGGSGGGGLNGPSSVGNGNSSNGSSNGNNNSSTGNGTSGGGGGNNAGGGGGGTNSNDGLHRNGGNGNSSCHEAGIGSLQNTADSKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQV---EVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFN---ELQNKLQDLKFDMGDYVCMKFLILLNPSVRGIVNRKTVSEGHDNVQAALLDYTLTCYPSVNDKFRGLVNILPEIHAMAVRGEDHLYTKHCAGSAPTQTLLMEMLHAKRKG--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:: ::*********************************:* ***. .:.* **********:******* ***:************************* * * :: : ..:: . . :: : : * : * : .: . . . . . .: : .* : . : . . * ::. . :: : : :: . *:: .: : * *:* : **.::* *:*** :.**:*:* *** **::.**::*::**: :::: * .. * .** .:* . . * . . :* :* *:.* : .*:**:**:. .:: : * *.. :::.:.***:*** ** ::* *: * *::::: ..::.* ** .. * :.**:***:**:. ", "identical_positions": 155, "similar_positions": 134, "identity": "14.98%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010509-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9T2-1", "uniprot_id": "D4A9T2_RAT", "id": "D4A9T2-1", "name": "", "aln": "MNSHHV-VLTLASLMFLM-CLPVSQSCNKALCASDVSKCLIQELCQCRPGEGNCPCCKECMLCLGALWDECCDCVGMCNPRNYSDTPPTSKSTVEELHEPIPSLFRALTEG----DTQLNWNIVSFPVAEELTHHENLVSFLETVNQPHHQNVSVPSNNVHAPFPSDKEHMCTVVYFDDCMSIHQCKISCESMGASKYRWFHNACCECVGPECIDYGSKTVKCMNCMF------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EP52-1", "uniprot_id": "TWSG1_MOUSE", "id": "Q9EP52-1", "name": "Twisted gastrulation protein homolog 1", "aln": "MKSHYI-VLALASLTFLL-CLPVSQSCNKALCASDVSKCLIQELCQCRPGEGNCPCCKECMLCLGALWDECCDCVGMCNPRNYSDTPPTSKSTVEELHEPIPSLFRALTEG----DTQLNWNIVSFPVAEELSHHENLVSFLETVNQLHHQNVSVPSNNVHAPFPSDKERMCTVVYFDDCMSIHQCKISCESMGASKYRWFHNACCECIGPECIDYGSKTVKCMNCMF------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZX9-1", "uniprot_id": "TWSG1_HUMAN", "id": "Q9GZX9-1", "name": "Twisted gastrulation protein homolog 1", "aln": "MKLHYVAVLTLAILMFLT-WLPESLSCNKALCASDVSKCLIQELCQCRPGEGNCSCCKECMLCLGALWDECCDCVGMCNPRNYSDTPPTSKSTVEELHEPIPSLFRALTEG----DTQLNWNIVSFPVAEELSHHENLVSFLETVNQPHHQNVSVPSNNVHAPYSSDKEHMCTVVYFDDCMSIHQCKISCESMGASKYRWFHNACCECIGPECIDYGSKTVKCMNCMF------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DGH0-1", "uniprot_id": "TWS1A_DANRE", "id": "Q9DGH0-1", "name": "Twisted gastrulation protein homolog 1-A", "aln": "MRPALFLCPVLISVLFLLSSLSLISGCNKALCASDVSKCLLQGLCQCRPQEGNCSCCKECMLCLSSLWEECCDCVGMCNPRSYNDSPATSKSTVEELYRPIPSLFRALTEG----DAPINMMVVSFPVAEELSHHENLVSFLETLDS-QSQNISLPTS------SAQDDALCTVVYFDDCVSIRQCKQYCESMGGSKYRWFHNACCECIGPECLDYGSKTVKCMNCLI------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W494-1", "uniprot_id": "Q9W494_DROME", "id": "Q9W494-1", "name": "", "aln": "MEIWRSLTVGTIVLLAIVCFYGTVESCNEVVCASIVSKCMLTQSCKC--ELKNCSCCKECLKCLGKNYEECCSCVELCPKPNDTRNSLSKKSHVEDFDG-VPELFNAVATPDEGDSFGYNWNVFTFQVDFDKYLKG---PKLEKDGHYFLRTNDKNLDEAIQERDNIVTVNCTVIYLDQCVSWNKCRTSCQTTGASSTRWFHDGCCECVGSTCINYGVNESRCRKCPESKGELGDELDDPMEEEMQDFGESMGPFDGPVNNNY-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZE5-1", "uniprot_id": "Q9VZE5_DROME", "id": "Q9VZE5-1", "name": "", "aln": "--------MKTLLTIYILLSFG---------------------------ELG--------LANMAQ---------------------MRKKSHTEEFEG-MPALFRAMSSS-PNDGYTYNWSVVSFSTN-------------GKPGS---------------------GLNCTVLYLDQCTSWNKCRQTCLKTGATSYRWFHDGCCECVGELCMNYGVNESRCRLCPEP--GLEDEDD--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54356-1", "uniprot_id": "TSG_DROME", "id": "P54356-1", "name": "Protein twisted gastrulation", "aln": "-MQLLCYFVILFVGIAPWSSLANDDGCNEVVCGSVVSKCLITQSCQC--KLNDCHCCKDCLNCLGELYIECCGCLDMCPKHKDVLPSLTPRSEIGDIEG-VPELFDTLTAE---DDEGWSTIRFSMRAGFKQRVQG---GASGDAGNGNGNGNAGSAG----------VTLCTVIYVNSCIRANKCRQQCESMGASSYRWFHDGCCECVGENCLNYGINESRCRGCPEDQDQLLTADTVP-AEAEQDLERFFGNEEIEDEWGYGEEDEFS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. :* :: :* ** ::: . . .:: . . ***:*.:.* .:*: * . *.:. ****:.****:* *::** : :* * ", "identical_positions": 26, "similar_positions": 35, "identity": "9.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010601-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P26640-1", "uniprot_id": "SYVC_HUMAN", "id": "P26640-1", "name": "Valine--tRNA ligase", "aln": "MSTLYVSPHPDAFPSLRALIAARYGEAGEGPGWGGAHPRICLQPPPTSRTPFPPPRLPALEQGPGGLWVWGATAVAQLLWPAGLGGPGGSRAAVLVQQWVSYADTELIPAACGATLPALGLRSSAQDPQ-AVLGALGRALSPLEEWLRLHTYLAGEAPTLADLAAVTALLLPFRYVLDPPARRIWNNVTRWFVTCVRQPEFRAVLGEVVLYSGARPLSHQPGPE-----------------APALPKTAAQLKKEAKKREKLEKFQQKQKIQQQQ--PPPGEKKPKPEKREKRDPGVITYDLPTPPGEKKDVSGPMPDSYSPRYVEAAWYPWWEQQGFFKPEYGRPNVSAANPRGVFMMCIPPPNVTGSLHLGHALTNAIQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLWREQGLSRHQLGREAFLQEVWKWKEEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAAVTEAFVRLHEEGIIYRSTRLVNWSCTLNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGVLVSFAYKVQGSDSDEEVVVATTRIETMLGDVAVAVHPKDTRYQHLKGKNVIHPFLSRSLPIVFDEFVDMDFGTGAVKITPAHDQNDYEVGQRHGLEAISIMDSRGALINVPPPFLGLPRFEARKAVLVALKERGLFRGIEDNPMVVPLCNRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQRTWHAWMDNIREWCISRQLWWGHRIPAYFVTVSDPAVPPGEDPDGRYWVSGRNEAEAREKAAKEFGVSPDKISLQQDEDVLDTWFSSGLFPLSILGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVMLGLKLTGRLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIYGISLQGLHNQLLNSNLDPSEVEKAKEGQKADFPAGIPECGTDALRFGLCAYMSQGRDINLDVNRILGYRHFCNKLWNATKFALRGLGKGFVPSPTSQPGGHESLVDRWIRSRLTEAVRLSNQGFQAYDFPAVTTAQYSFWLYELCDVYLECLKPVLNGVD---QVAAECARQTLYTCLDVGLRLLSPFMPFVTEELFQRLPRRMP-QAPPSLCVTPYPEPSECSWKDPEAEAALELALSITRAVRSLRADYNLTRIRPDCFLEVADEATGALASAVSGYVQALASAGVVAVLALGAPAPQGCAVALASDRCSIHLQLQGLVDPARELGKLQAKRVEAQRQAQRLRERRAASGYPVKVPLEVQEADEAKLQQTEAELRKVDEAIALFQKML", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q740-1", "uniprot_id": "F1Q740_DANRE", "id": "F1Q740-1", "name": "Valine--tRNA ligase", "aln": "MDTLYISSHPDDFRSLLPLIAAGFCPS---------PPRILHQDPP---AELARSRPALVLAGAGGTVLSGTSAVSWYLAATGKRAGSDKKQESQVWQWLSFAENELTPVACAVAFPLLGIMGVDKKLQQSSRAELLRVLKALDGTLALRTFLVGESVTLADAAVAMAALLPFKYALEPADRKSLVNVTRWFNTCVNQPQFLKVLGKISLCEKMVPVTPKPNTASNVTVTAAAAAKPDSGPANGPPKTEAQLKKEAKKREKMEKFQQKKDMEEKKKMQPQTEKKAKPEKKE---LGVITYNVSTPPGEKKDVLSPLPDSYSPQYVEAAWYSWWEKQGFFKPEYGRKKLSEPNPRGVFMMCIPPPNVTGSLHLGHALTNAIQDCLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLMRERKMTRHDLGRENFIKEVWKWKNEKGDRIYHQLKKLGSSLDWDRACFTMDDKLSFAVQEAFIRMHEEGVIYRSKRLVNWSCTLNSAISDIEVDKKELTGRTLLPVPGYKDKVVFGVLVSFSYKIEGSD--EEVIVATTRIETMLGDTAVAVHPEDSRYKHLKGKMVIHPFCDRKMPVVFDDFVDMNFGTGAVKITPAHDHNDYEVGERHKLPFINILDENGLLINVPPPFLGMKRFEARTAVLQALKDRGQFKEVKDNPMVVPVCSRSKDIVEPLLKPQWYVDCREMGKQAADVVRNGELKIIPDHHLKTWFNWMDNIRDWCISRQLWWGHRIPAYFVTVNDPAVKPGEDVDGHYWVSGRSEQEAREKAAKRFNVTADKISLRQDEDVLDTWFSSGIFPFSIFGWPNESEDLRVFYPGTLLETGHDILFFWVARMVMMGLKLTGKLPFKEVYLHAVVRDAHGRKMSKSLGNVIDPLDVITGISLEGLYAQLADSNLDPLEIEKAKQGQKSDYPTGIPECGTDALRFALCAYTSQGRDINLDVNRILGYRHFCNKLWNAVKFAMRTLGEGFVPCEKAQLCGSESVSDRWILSRLSAAVALCDGGFKAYDFPTITTAIYNFWLYELCDVYLECVKPVFSRTDSKGQKQADVCRQTLYTCLEVGLRLLSPIMPFVSEELFQRLPRRRPRDSPPSISVTPYPDTAEFCWHSEDVDRQMEFVMSVVRTIRSLRADYNLTKTRADCFLQCIDSETAALVQKYSLQIQTLSYSQAVHSVVGDAAIPQGCAVAIASDKCTVNLMLKGLIDLGKEVTKLTAKKGELEKQMEKMKEKMTKNDYKEKVPVKVQEADAEKLRQSEAELQKVKEAIENFSKMM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.***:*.*** * ** .**** : : *** * ** : :. .* . : *.** : *::**: * .:* . ...: * **:*:*:.** *.**..::* **: . :. * : . * *.*..*: * *:*:*.**: **** *.. * ****:*.*:*. *: ****** ***.**:* ***:: * . *:: :*.. * . *** ************:******:.::::: * ***.****:* *****::.********* .*:******:*******.***:********** ::* .*******************************.********************************* **: ::**:**** *::******:*************************** *** ** ***:*:****:****.*****************************.*****:** *******:**::*** ***:************.******:*:**:***** ***** .*.:*:***:****:*************:******:** * *.*:*..* **********: *****.*** ***:** *: ::*******:*.****:*****:***** * **.: *: .* .*:*:*:*: * :**. ******:********************.**** **** **:******.* ********.*.*:.*****:*************:**:**:****:**** ************************:******:***:******:*********************** ****:**: ** :***** *:****:***:*:*:************.**** **************************.***:* **:****. .:* * **: **** ***: ** *.: **:*****::*** *.*************:***:. .* * *: .********:********:****:********** * ::***:.*****:.:* .*:. :.: :*:.:*:.*::**********: *.****: *. *.**.. * :*:*: : .* :. .*. *******:***:*:::* *:**:* .:*: ** **: * ::* ::::*: : ..* ***::***** **:*:****:**.*** *.**:", "identical_positions": 837, "similar_positions": 256, "identity": "64.98%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010605-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54844-1", "uniprot_id": "MAF_RAT", "id": "P54844-1", "name": "Transcription factor Maf", "aln": "-------------------------------------------------------------------------------------MASELAMNNSDLPTSPLAMEYVNDFDLMKFEVKKEPVETDRIISQCGRLIAGGSLSSTPMSTPCSSVPPSPSFSAPSPASGSEQKAHLEDYYWMTGYPQQLNPEALGFSPEDAVEALISNSHQLQGGFDGYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGG-------------------------APHYHHHHHH--------ATGHHHHPTAGAPGAAGSASASASGAGGAGGGGPASAGGGGGGGGGG----------------------TAGAGGALHPHHAAGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHLKQEISRLVRERDAYKEKYEKLVSSGFRENCSSSDN--PSSPEFFM--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54843-1", "uniprot_id": "MAF_MOUSE", "id": "P54843-1", "name": "Transcription factor Maf", "aln": "-------------------------------------------------------------------------------------MASELAMNNSDLPTSPLAMEYVNDFDLMKFEVKKEPVETDRIISQCGRLIAGGSLSSTPMSTPCSSVPPSPSFSAPSPGSGSEQKAHLEDYYWMTGYPQQLNPEALGFSPEDAVEALISNSHQLQGGFDGYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGA-------------------------APHYHHHHHH--------AAGHHHHPTAGAPGAAGGASASASGAGGAGGGGPASAGGGGGGGGGGG---------------------TAGAGGALHPHHAAGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHLKQEISRLVRERDAYKEKYEKLVSNGFRENGSSSDN--PSSPEFFM--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75444-2", "uniprot_id": "MAF_HUMAN", "id": "O75444-2", "name": "Transcription factor Maf", "aln": "-------------------------------------------------------------------------------------MASELAMSNSDLPTSPLAMEYVNDFDLMKFEVKKEPVETDRIISQCGRLIAGGSLSSTPMSTPCSSVPPSPSFSAPSPGSGSEQKAHLEDYYWMTGYPQQLNPEALGFSPEDAVEALISNSHQLQGGFDGYARGAQQLAAAAGAGAGASLGGSGEEMGPAAAVVSAVIAAAAAQSGA-------------------------GPHYHHHHHH--------AAGHHHHPTAGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGG------------------GGGAAGAGGALHPHHAAGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHLKQEISRLVRERDAYKEKYEKLVSSGFRENGSSSDN--PSSPEFFM--------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P0X6-1", "uniprot_id": "A0A8M9P0X6_DANRE", "id": "A0A8M9P0X6-1", "name": "Transcription factor Maf", "aln": "-------------------------------------------------------------------------------------MASELALSSSDLPTSPLAMEYVNDFDLMKFEVKKEPLEPDRSISQCSRLIAGGSLSSTPMSTPCSSVPPSPSFSAPSPGSGNEQKAHLEDFYWMTGYQQQLNPEALGFSPEDAVEALINSTHQLQS-YDGYARG-QQFSNTAGTGG----AMAGEEMGSAAAVVSAVIAAAAAQNG--------------------------APHHHHHHHH--------HGHHQQHQTPGVPSSTNSPVA----------------------------------------------------------HHQHS--HLDDRFSDDQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRYKRVQQRHILEGEKTQLIQQVDHLKQEISRLVRERDAYKEKYEKLVNSGFRENSSSSDNN-PSSPEFFMSSRKFLHL------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PG80-1", "uniprot_id": "M9PG80_DROME", "id": "M9PG80-1", "name": "", "aln": "MKMEDPTINDTYVQEFDLHHLEVGGNGAGQSHGAGAASQVTTLGHVKREDHSPPQPVAVKWTTIHGDPTNPDDDPDSLPLSGPEPAGAVEVSPSPHIKLRSFSGHHQWHMDERRLQPLSPPPEQYGPLPGQAILVNTSSGAGVPGGVPSTPPETPPVVGSPTGSSSCPAQTYAHHYARTPGSSVSVSASAAAAAAASAGAASVSAGLSHDMMWLTNSIRADQQPLDLRPLPYPGSQEEAEEWDRQRDYALQAAAAHHHHHGQPLMQAQHHPHGHGGHPHQVMLQQSKYPHHHHHHFHNLELTPINMHSNSYGSASGALTPTCLPQVPSNGSGSSGGGGGSGSGSGGPGSVGGGSCVITRAALQPCRPLSASSTRSSNNMSPRTCSGAYSNATLEDCLNDDMLTTLTVRELNKRLHGCPREEVVRLKQKRRTLKNRGYAQNCRSKRLHQRHELEKANRVLNQDLHRLKLEYSRVCQERDALMQRLQRAANGGVGAGGATAGGDSQSSPEFYLXRQLAVASGSSASSSSSSQQQQQHPQQLHLQHRGPQWNPQQLVN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . ...: .:: .: .:* ::: . * * :. . *: .* :..* ..*.:. ..* ..:*: .*. ::: ..: .* .:...* . :. .* * :. . : : : :* . . .** . . . ** : * **:****.* : :.*. .: . . . ::* :.*: *.*::*****::*:* .:***:****************.** **::*** ** : * *::.:** * **: :**** :: :: ...*. . :::.. *****:: ", "identical_positions": 84, "similar_positions": 120, "identity": "15.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010605-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZNT6-1", "uniprot_id": "MAFA_RAT", "id": "D3ZNT6-1", "name": "Transcription factor MafA", "aln": "MAAELAMGAELPSSPLAIEYVNDFDLMKFEVKKEPPEAERFCHRLPPGSLSSTPLSTPCSSVPSSPSFCAPSPGTG--SSAGGGGSAAQAGGAPGPPSGGPGTVGGASGKAVLEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHSAHHGAHHPAAAAAYEAFRGQSFAGGGGGGADDMGAGHHHGAHHTAHHHHSAHHHHHHHHHHGGSGHHGGGAGHGGGGAGHHVRLEERFSDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLEVGRLAKERDLYKEKYEKLAGRGGPGGAGGAGFPREPSPAQAGPGAAKGAPDFFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CF90-1", "uniprot_id": "MAFA_MOUSE", "id": "Q8CF90-1", "name": "Transcription factor MafA", "aln": "MAAELAMGAELPSSPLAIEYVNDFDLMKFEVKKEPPEAERFCHRLPPGSLSSTPLSTPCSSVPSSPSFCAPSPGTG--GGAGGGGSAAQAGGAPGPPSGGPGTVGGASGKAVLEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGQSFAGGGG--ADDMGAGHHHGAHHTAHHHHSAHHHHHHHHHHGGSGHHGGGAGHGGGGAGHHVRLEERFSDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLEVGRLAKERDLYKEKYEKLAGRGGPGGAGGAGFPREPSPAQAGPGAAKGAPDFFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NHW3-1", "uniprot_id": "MAFA_HUMAN", "id": "Q8NHW3-1", "name": "Transcription factor MafA", "aln": "MAAELAMGAELPSSPLAIEYVNDFDLMKFEVKKEPPEAERFCHRLPPGSLSSTPLSTPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAGGGG--ADDMGAGHHHGAHHAAHHHHAAHHHHHHHHHHGG-------AGHGGG-AGHHVRLEERFSDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLEVGRLAKERDLYKEKYEKLAGRGGPGSAGGAGFPREPSPPQAGPGGAKGTADFFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KMR8-1", "uniprot_id": "MAFA_DANRE", "id": "A3KMR8-1", "name": "Transcription factor MafAa", "aln": "MATDLAMSAELPNSPLAIEYVNDFDLMKFEIKKEPPEADRYCHRLPPGSLSSTPISTPCSSVPSSPSFCAPSPGSQ-----PGQNLVNGVNNNNNNSGNGNNNTQGSSGKPQMEDLYWIPNYQHHISPEALNLTPEDAVEALIGNAHHHHHHHHHQP-----YEGFRGQQYVG------EDLSAATNG-------HHHPVHHHHHHHGHH------------------AHARLEDRFSDEQLVSMTVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRYKRVQQRHMLESEKCTLQSQVEQLKQDVARLIKERDLYKEKYEKLASR----AFNGGGNTRDPS---SGNHVKTTSTDFFM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::***.****.*****************:*******:*:*************:*******************: * . ... . ...* . . *:***. :*****:..****:.*****************..** ** *:* **.*** :.* :*:.*. : ***..******* ** *.***:****:*****:************************************:*******:****** ********* :*.** **************.* . .*.* .*:** :* . :.***:", "identical_positions": 222, "similar_positions": 59, "identity": "61.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010605-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P14630-1", "uniprot_id": "APOM_RAT", "id": "P14630-1", "name": "Apolipoprotein M", "aln": "-MFHQVWAALLYLYGLLFNSMNQCPEHSQLMTLGMDDKETPEPHLGLWYFIAGAAPTMEELATFDQVDNIVFNMAAGSAPRQLQLRATIRTKNGVCVPRKWTYHLTEGKGNTELRTEGRPDMKTDLFSISCPGGIMLKETGQGYQR-FLLYNRSPHPPEECVEEFQSLTSCLDF--KAFLVTPRNQEACPLSSK-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1R3-1", "uniprot_id": "APOM_MOUSE", "id": "Q9Z1R3-1", "name": "Apolipoprotein M", "aln": "-MFHQVWAALLSLYGLLFNSMNQCPEHSQLTALGMDDTETPEPHLGLWYFIAGAASTTEELATFDPVDNIVFNMAAGSAPRQLQLRATIRTKSGVCVPRKWTYRLTEGKGNMELRTEGRPDMKTDLFSSSCPGGIMLKETGQGYQR-FLLYNRSPHPPEKCVEEFQSLTSCLDF--KAFLVTPRNQEACPLSSK-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95445-1", "uniprot_id": "APOM_HUMAN", "id": "O95445-1", "name": "Apolipoprotein M", "aln": "-MFHQIWAALLYFYGIILNSIYQCPEHSQLTTLGVDGKEFPEVHLGQWYFIAGAAPTKEELATFDPVDNIVFNMAAGSAPMQLHLRATIRMKDGLCVPRKWIYHLTEG--STDLRTEGRPDMKTELFSSSCPGGIMLNETGQGYQR-FLLYNRSPHPPEKCVEEFKSLTSCLDS--KAFLLTPRNQEACELSNN-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NXE0-1", "uniprot_id": "A0A8M1NXE0_DANRE", "id": "A0A8M1NXE0-1", "name": "", "aln": "MIAATLWGLVSSVMGLFYVGLQVMVPCLPPAPLSTSVINT-DEYTGTWYFVAAAVWDEDDLKTLQTTDSIVLQIQKNSD-STLKVTETMRIGDACLKNVTNYYALPATSPFLFREDFDTIAVIWDGKYINCPTCIIMLYVGEDEEMNTFLFSRDEKTTEEAIQEFKSKTECLLM--EDMWRAPLKNGYCKVDDSA------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P02763-1", "uniprot_id": "A1AG1_HUMAN", "id": "P02763-1", "name": "Alpha-1-acid glycoprotein 1", "aln": "----MALSWVLTVLSLLPLLEAQIPLCANLVPVPIT-NATLDRITGKWFYIASAFRNEEYNKSVQEIQATFFYFTPNKTEDTIFLREYQTRQDQCIYN-TTYLNVQRENGTISRYVGGQEHFAHLLILRDTKTYMLAFDVNDEKNWGLSVYADKPETTKEQLGEFYEALDCLRIPKSDVVYTDWKKDKCEPLEKQHEKERKQEEGES", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . .:: .: : * *:::*.* : :.: : .: : .. : : . . : . . . :: ..: : :: . ...:: : ** . .** . . : :: * .. ", "identical_positions": 9, "similar_positions": 55, "identity": "4.35%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010606-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09803-1", "uniprot_id": "CADH1_MOUSE", "id": "P09803-1", "name": "Cadherin-1", "aln": "-------------MGARCRSFSALLLLLQVSSWLCQELEPES--CSPGFS-SEVYTFPVPERHLERGHVLGRVRFEGCTGRPRTAFFSEDSRFKVATDGTITVKRHLKLHKLETSFLVRARDSSHRELSTKVTLKSMGHHHHRHHHRDPASESNPELLMFPSVYPGLRRQKRDWVIPPISCPENEKGEFPKNLVQIKSNRDKETKVFYSITGQGADKPPVGVFIIERETGWLKVTQPLDREAIAKYILYSHAVSSNGEAVEDPMEIVITVTDQNDNRPEFTQEVFEGSVAEGAVPGTSVMKVSATDADDDVNTYNAAIAYTIVSQDPELPHKNMFTVNRDTGVISVLTSGLDRESYPTYTLVVQAADLQGEGLSTTAKAVITVKDINDNAPVFNPSTYQGQVPENEVNARIATLKVTDDDAPNTPAWKAVYTVVN-DPDQQFVVVTDPTTNDGILKTAKGLDFEAKQQYILHVRVENEEPFEGSLVPSTATVTVDVVDVNEAPIFMPAERRVEVPEDFGVGQEITSYTAREPDTFMDQKITYRIWRDTANWLEINPETGAIFTRAEMDREDAEHVKNSTYVALIIATDDGSP-IATGTGTLLLVLLDVNDNAPIPEPRNMQFCQRNPQPHIITILDPDLPPNTSPFTAELTHGASVNWTIEYNDAAQESLILQPRKDLEIGEYKIHLKLADNQNKDQVTTLDVHVCDCEGTVNNCMKAGIVAAGLQVPAILGILGGILALLILILLLLLFLRRRTVVKEPLLPPDDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVT-RNDVAPTLMSVPQYRPRPANPDEIGNFIDENLKAADSDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDQDQDYDYLNEWGNRFKKLADMYGGGEDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R0T4-1", "uniprot_id": "CADH1_RAT", "id": "Q9R0T4-1", "name": "Cadherin-1", "aln": "-------------MGARCRSFSALLLLLQVSSWLCQQPESESDSCRPGFS-SEVYTFLVPERHLERGHILGRVKFEGCTGRPRTAFFSEDSRFKVSTDGVITVKRHLKLHKLETSFLVHAWDSSYRKLSTKVTLKSLGHHHHRHHHRDPVSESNPELLTFPSFHQGLRRQKRDWVIPPINCPENQKGEFPQRLVQIKSNRDKETTVFYSITGPGADKPPVGVFIIERETGWLKVTQPLDREAIDKYLLYSHAVSSNGEAVEDPMEIVVTVTDQNDNRPEFIQEVFEGSVAEGALPGTSVMQVSATDADDDINTYNAAIAYTILSQDPELPHKNMFTVNRDTGVISVVTSGLDRESYPTYTLVVQAADLQGEGLSTTAKAVITVKDINDNAPIFNPSTYQGQVLENEVGARIATLKVTDDDAPNTPAWNAVYTVVN-DPDHQFTVITDPKTNEGILKTAKGLDFEAKQQYILHVTVENEEPFEGSLVPSTATVTVDVVDVNEAPIFVPAEKRVEVPEDFGVGLEIASYTAREPDTFMEQKITYRIWRDTANWLEINPETGVISTRAEMDREDSEHVKNSTYTALIIATDDGSP-IATGTGTLLLVLSDVNDNAPIPEPRNMQFCQRNPKPHVITILDPDLPPNTSPFTAELTHGASVNWTIEYNDAEQESLILQPRKDLEIGEYKINLKLSDNQNKDQVTTLEVHVCDCEGTVNNCMKAISLEAGLQVPAILGILGGILALLILILLLLLFLRRRTVVKEPLLPPDDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVI-RNDVAPTLMSMPQYRPRPANPDEIGNFIDENLKAADSDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDQDQDYDYLNEWGNRFKKLADMYGGGEED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12830-1", "uniprot_id": "CADH1_HUMAN", "id": "P12830-1", "name": "Cadherin-1", "aln": "-------------MGPWSRSLSALLLLLQVSSWLCQEPEP----CHPGFD-AESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILN-DDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSP-VATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVT-RNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LL01-1", "uniprot_id": "A0ABK0LL01_RAT", "id": "A0ABK0LL01-1", "name": "", "aln": "MHRGTLWCNYILGIVCLEG-RMLGSHLHQVCWLRSVVSES----YREDFIREAGVTLEVGGTDLEPSQALEKEALAG------HEVLGADS------GGIITLN--------------------------------------RETVQGGKGVMNS------PPSRILRRRKREWVMPPISVPENGKGPFPQRLNQLKSNKDRGTKLFYSITGPGADSPPEGVFTIEKETGWLLLNMPLDREKIVKYELFGHAVSENGASVEEPMNISIIVTDQNDNKPKFTQDTFRGSVPEGVMPGTSVMQVTATDEDDAINTYNGVVAYSIHSQEPKEPHDLMFTIHKSTGTISVISSGLDREKVPEYTLTIQATDMDGDGSTTTAEAVVQILDTNDNAPEFQPQKYEAWVPENAVGHEVQRLTVTDLDSPNSPAWRATYHIVGGDDGDHFTVATHPETNQGILTTKKGLDFEAQNQHTLYIEVTNEASFAVKLPTATATVVVHVEDVNEAPVFVPPSKVIEAQEGISIGELVCVYTAQDPDK-EEQKISYSILRDPASWLAVDPDSGQITAAGILDREDEQFVKNDIYEVMVLATDNGNP-PTTGTGTLLLTLTDINDHGPIPEPRQIIICNQSPVPQVLNITDKDLSPNSSPFQAQLTHDSDIYWMAEVSEKG-DTVALSLKKFLKQDTYDLHLSLSDHGNREQLTMIRATVCDCHGQVLNDCPRPWKGG-----FILPVLGAVLALLTLLLALLLLVRKKRKVKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDITQLHRGLEARPEVVLRNDVAPTFIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDSLLVFDYEGSGSDAASLSSLTSSTSDQDQDYNYLTEWGSRFKKLADMYGGGEDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10287-1", "uniprot_id": "CADH3_MOUSE", "id": "P10287-1", "name": "Cadherin-3", "aln": "-------------MELLSGPHAFLLLLLQVCWLRSVVSEP----YRAGFIGEAGVTLEVEGTDLEPSQVLGKVALAG------QGMHHADN------GDIIMLT--------------------------------------RGTVQGGKDAMHS------PPTRILRRRKREWVMPPIFVPENGKGPFPQRLNQLKSNKDRGTKIFYSITGPGADSPPEGVFTIEKESGWLLLHMPLDREKIVKYELYGHAVSENGASVEEPMNISIIVTDQNDNKPKFTQDTFRGSVLEGVMPGTSVMQVTATDEDDAVNTYNGVVAYSIHSQEPKEPHDLMFTIHKSTGTISVISSGLDREKVPEYRLTVQATDMDGEGSTTTAEAVVQILDANDNAPEFEPQKYEAWVPENEVGHEVQRLTVTDLDVPNSPAWRATYHIVGGDDGDHFTITTHPETNQGVLTTKKGLDFEAQDQHTLYVEVTNEAPFAVKLPTATATVVVHVKDVNEAPVFVPPSKVIEAQEGISIGELVCIYTAQDPDK-EDQKISYTISRDPANWLAVDPDSGQITAAGILDREDEQFVKNNVYEVMVLATDSGNP-PTTGTGTLLLTLTDINDHGPIPEPRQIIICNQSPVPQVLNITDKDLSPNSSPFQAQLTHDSDIYWMAEVSEKG-DTVALSLKKFLKQDTYDLHLSLSDHGNREQLTMIRATVCDCHGQVFNDCPRPWKGG-----FILPILGAVLALLTLLLALLLLVRKKRKVKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDITQLHRGLEARPEVVLRNDVVPTFIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDSLLVFDYEGSGSDAASLSSLTTSASDQDQDYNYLNEWGSRFKKLADMYGGGEDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22223-1", "uniprot_id": "CADH3_HUMAN", "id": "P22223-1", "name": "Cadherin-3", "aln": "-------------MGLPRG-PLASLLLLQVCWLQCAASEP----CRAVFR-EAEVTLEAGGAEQEPGQALGKVFMGCPG--QEPALFSTDN------DDFTVRN--------------------------------------GETVQERRSLKERNPLKIFPSKRILRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAVEKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQATDMDGDGSTTTAVAVVEILDANDNAPMFDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDFEAKNQHTLYVEVTNEAPFVLKLPTSTATIVVHVEDVNEAPVFVPPSKVVEVQEGIPTGEPVCVYTAEDPDK-ENQKISYRILRDPAGWLAMDPDSGQVTAVGTLDREDEQFVRNNIYEVMVLAMDNGSP-PTTGTGTLLLTLIDVNDHGPVPEPRQITICNQSPVRQVLNITDKDLSPHTSPFQAQLTDDSDIYWTAEVNEEG-DTVVLSLKKFLKQDTYDVHLSLSDHGNKEQLTVIRATVCDCHGHVET-CPGPWKGG-----FILPVLGAVLALLFLLLVLLLLVRKKRKIKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDITQLHRGLEARPEVVLRNDVAPTIIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDTLLVFDYEGSGSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGEDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90Z37-1", "uniprot_id": "CADH1_DANRE", "id": "Q90Z37-1", "name": "Cadherin-1", "aln": "-------------MACVTTVGLGVIFFLFRVFSSGYTHMS---ICTPGFE-LEEFVFKVHRNHLHSGKRLGKVTFNNCDGRTRTLFQSIDKRFEINTDGTVTLKRQVTLHEGHKVFSVHAWDSS--------------GMKHTASVRVERVPAQVESSSDVDLTK-NKRVKRGWIIPPISVSENSKGPFPMRLVQIKSDYAIETRLAYKITGEGADLDPKGIFTIDRLSGWVSVTQLLDREKKASYKLRAHANGVDADVTEKPMDIIVTVTDQNDNKPVFTQNPFNGNVPEALEKGEVFMTVTATDADDKENTDNADISYVIISQDPPSPKPNMFAINPVSGGISVLEKGLDREQWFRYTLVITATDMNGEGLSTTGTAVITVTDSNDNAPLFEQSSYTASVPENQVGVEVAKLPVTDGDEPESTAWSTKYQIIAGDKGGFFNISTGPSRLEGIITTVKPLDYEKTKQYILSVIVVNDDKFVGPLPTSTATVTVNVKDVNEPPEFIPKEKFISRPENLPVGSNLIPFTAIDPDTEKKQNITYRIGNDPSDWLNITG-SGQIQVKNALDRESS-NVKDGKYKALILALDNDVESPATGTGTLVIELQDVNDNAPVINERTIKLCNRESAPVLLSITDKDLPPFAGPFKVEPQGDTSKNWSVFFNETG-HFLNIKPQSQLEQGEYKVVLRVADREGESQENIIQASVCDCKGEAFQCTDKQVAGIP--LFGVLGVLGGILLLLLLALLLLMFLRRKSNSKKEPLLPEDDVRDNIYYYDEEGGGEDDQDFDLSVLHRGLDNRPEVF-RNDVAPTFMPAPQYRPRPANPEEIGTFIDDNLKAADNDPTAPPYDSLLVFDYEGGGSDAGSLSSLNTSSSGNDQDYDFLNEWGPRFKKLADMYGGGED-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . * .: . . . .: * : : *. .. . : . :* ** *::.** .** ** ** .* *:**: : *.*** *** * *:* ::: :**: : **** .* * .** . :. .*.**:* : ******::* * *: *.*.* *. * .* *:*** ** * *. ::* * **:* *. **::: :* ***: .*****. * *.: *:*::*:* :**. **: : * ***.* *: .* . * ** .. : * *** * *::.** : * :: * . * : * * :*::.* * **:* .*: * : * * * * .:***:.*.* ****.* *:* .: :. *.: * : :** :**. .*:*:* * .*.:.** : :* : . :***. *::. * .:::* *.. :******:: * *:**:.*: : * : :*::.. ::.* * **.* :.** .: .:. * .: . : :. : *: . *.: * : *. ...* . : . ****.* . :* :**.:* ** * * **:::*:: *: * *:**.***::**.******:***:*:: *****: **** ****.**::. * * ******:***.** :*****:.********:********.**:*.*****.:* *.:****::*.*** *************: ", "identical_positions": 303, "similar_positions": 223, "identity": "33.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010607-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63279-1", "uniprot_id": "UBC9_HUMAN", "id": "P63279-1", "name": "SUMO-conjugating enzyme UBC9", "aln": "MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63281-1", "uniprot_id": "UBC9_RAT", "id": "P63281-1", "name": "SUMO-conjugating enzyme UBC9", "aln": "MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63280-1", "uniprot_id": "UBC9_MOUSE", "id": "P63280-1", "name": "SUMO-conjugating enzyme UBC9", "aln": "MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9DDJ0-1", "uniprot_id": "UBC9B_DANRE", "id": "Q9DDJ0-1", "name": "SUMO-conjugating enzyme UBC9-B", "aln": "MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFSP--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KNM2-1", "uniprot_id": "Q7KNM2_DROME", "id": "Q7KNM2-1", "name": "", "aln": "MSGIAITRLGEERKAWRKDHPFGFVARPAKNPDGTLNLMIWECAIPGKKSTPWEGGLYKLRMIFKDDYPTSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAITIKQILLGIQDLLNEPNIKDPAQAEAYTIYCQNRLEYEKRVRAQARAMAATE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50623-1", "uniprot_id": "UBC9_YEAST", "id": "P50623-1", "name": "SUMO-conjugating enzyme UBC9", "aln": "MSSLCLQRLQEERKKWRKDHPFGFYAKPVKKADGSMDLQKWEAGIPGKEGTNWAGGVYPITVEYPNEYPSKPPKVKFPAGFYHPNVYPSGTICLSILNEDQDWRPAITLKQIVLGVQDLLDSPNPNSPAQEPAWRSFSRNKAEYDKKVLLQAKQYSK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.:.: ** :*** ********* * *.*:.**:::* **..****:.* * **:: : : : ::**:.*** ** . ::*********:***:*:*::*******:***:**:*:**:.** :.*** *: :.:*: **:*:* **: : ", "identical_positions": 81, "similar_positions": 49, "identity": "50.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010608-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48986-1", "uniprot_id": "NDF6_MOUSE", "id": "P48986-1", "name": "Neurogenic differentiation factor 6", "aln": "MLTLPFDESVVMPESQMCRKFARQCEDQKQIKKPESFPKQVVLRGKSIKRAPGEETEKEEEEEDREEEDENGLSRRRGLRKKKTTKLRLERVKFRRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRIGKRPDLLTFVQNLCKGLSQPTTNLVAGCLQLNARSFLMGQ-GGEAAHHTRSPYSTFYPPYHSPELATPPGHGTLDNSKSMKPYNYCSAYESFYESTSPECASPQFEGPLSPPPINYNGIFSLKQEETLDYGKNYNYGMHYCAVPPRGPLGQGAMFRLPTDSHFPYDLHLRSQSLTMQDELNAVFHN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96NK8-1", "uniprot_id": "NDF6_HUMAN", "id": "Q96NK8-1", "name": "Neurogenic differentiation factor 6", "aln": "MLTLPFDESVVMPESQMCRKFSRECEDQKQIKKPESFSKQIVLRGKSIKRAPGEETEKEEEEEDREEEDENGLPRRRGLRKKKTTKLRLERVKFRRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRIGKRPDLLTFVQNLCKGLSQPTTNLVAGCLQLNARSFLMGQ-GGEAAHHTRSPYSTFYPPYHSPELTTPPGHGTLDNSKSMKPYNYCSAYESFYESTSPECASPQFEGPLSPPPINYNGIFSLKQEETLDYGKNYNYGMHYCAVPPRGPLGQGAMFRLPTDSHFPYDLHLRSQSLTMQDELNAVFHN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYU3-1", "uniprot_id": "NDF6A_DANRE", "id": "Q6NYU3-1", "name": "Neurogenic differentiation factor 6-A", "aln": "MLTLPFEDPVIM-DTQFGANFPRDCVGDLKGNKQEPFEKEETLS----HVMDDDDSEKDEDERE-DGQDENGLPRRRGPRKKKMTKARVDRVKVRRMEANARERNRMHGLNNALDSLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILSTGKRPDLLTFVQTLCKGLSQPTTNLVAGCLQLNARNFIPDQISGEASFSGRSPYESVYSTYHSPSVVTPSGP-SVDAVKPFRSFNYCSSYESFYESVSPECGSPQFEGPLSPP-INFNGIFSLKHEEPVEYGKSCHYGTRYCAVPPRASIGQSARG--SSDLHFPYDIHLRGQFYPVQDELN-TFHN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******::.*:* ::*: :*.*:* .: : :* *.* *: .* : .:::**:*:*.: : :*****.**** **** ** *::***.** **************:***.********************************** ***********.**********************.*: .* .***:. ****.:.*..****.:.**.* ::* *.::.:****:*******.****.*********** **:*******:**.::***. :** :*******..:**.* .:* *****:***.* .:***** .***", "identical_positions": 215, "similar_positions": 79, "identity": "63.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010608-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48986-1", "uniprot_id": "NDF6_MOUSE", "id": "P48986-1", "name": "Neurogenic differentiation factor 6", "aln": "MLTLPFDESVVMPESQMCRKFARQCEDQKQIKKPESFPKQVVLRGKSIKRAPGEETEKEEEEEDREEEDENGLSRRRGLRKKKTTKLRLERVKFRRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRIGKRPDLLTFVQNLCKGLSQPTTNLVAGCLQLNARSFLMGQGGEAAHHTRSPYSTFYPPYHSPELATPPG--HGTLDNSKSMKPYNYCSAYESFYESTSPECASPQFEGPLSPPPINYNGIFSLK-QEETLDYGKNYNYGMHYCAVPPRGPLGQGAMFRLPTDSHFPYDLHLRSQSLTMQDELNAVFHN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96NK8-1", "uniprot_id": "NDF6_HUMAN", "id": "Q96NK8-1", "name": "Neurogenic differentiation factor 6", "aln": "MLTLPFDESVVMPESQMCRKFSRECEDQKQIKKPESFSKQIVLRGKSIKRAPGEETEKEEEEEDREEEDENGLPRRRGLRKKKTTKLRLERVKFRRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRIGKRPDLLTFVQNLCKGLSQPTTNLVAGCLQLNARSFLMGQGGEAAHHTRSPYSTFYPPYHSPELTTPPG--HGTLDNSKSMKPYNYCSAYESFYESTSPECASPQFEGPLSPPPINYNGIFSLK-QEETLDYGKNYNYGMHYCAVPPRGPLGQGAMFRLPTDSHFPYDLHLRSQSLTMQDELNAVFHN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W6C7-1", "uniprot_id": "NDF6B_DANRE", "id": "Q9W6C7-1", "name": "Neurogenic differentiation factor 6-B", "aln": "MLTVPFEEPDMMRESQFGATFTRQ-EDVR------------TLSSAELKEAEDDNTDREEEEE--REEDENGLPKKKGPRKKKS-EGRGDRVKMRRQEANARERSRMHGLNDALESLRKVVPCYSKTQKLSKIETLRLAKNYIWALSETLSAGKRPDLLAFVQTLCKGLSQPTTNLVAGCLQLNARNFLTDHNGDVSFSGRPAYDSLYP-YPNAEMATPTGLSSGTRESVKPFRPYNYYASYESYYDSASPESSSPHFDGQMSPP-INYNGIFSLKKHDEQVEYSKNCHYGMRYCNVP-----GRGSMYRVSPDSHFPYDLHPRSQSFQSQDELNTGYHN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:**:*. :* ***: .*:*: ** : .* . .:*.* .::*::***** .*******.:::* ****: : * :***:**********.*********:.******************************** * *******:***.**********************.** .:.*:.:. *..*.::** * ..*::**.* ** :. *.::**** ::***:*:*:***.:**:*:* :*** ********** ::* ::*.** :***:** ** *:*:*:*:..********* ****: *****: :**", "identical_positions": 202, "similar_positions": 82, "identity": "59.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010608-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q15784-1", "uniprot_id": "NDF2_HUMAN", "id": "Q15784-1", "name": "Neurogenic differentiation factor 2", "aln": "MLTRLFSEPGLLSDVPKFASWGDGEDDEPRSDKGDAPPPPPPAPGPGAPGPARAAKPVPLRG-EEGTEATLAEVKEEGELGGEE--EEEEEEEEGLDEAEGERPKKRGPKKRKMTKARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGKRPDLVSYVQTLCKGLSQPTTNLVAGCLQLNSRNFLTEQGADGAGRFHGSGGPFAMHPYPYPCSRLAGAQCQAAGGLGGGAAHALRTHGYCAAYETLYAAAGGGGASPDYNSSEYEGPLSPPLCLNGNFSLKQDS--SPDHEKSYHYSMHYSALPGSRP-TGHGLVFGSSAVRGG-VHSENL-LSYDMHLHHDRGPMYEELNAFFHN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62414-1", "uniprot_id": "NDF2_MOUSE", "id": "Q62414-1", "name": "Neurogenic differentiation factor 2", "aln": "MLTRLFSEPGLLSDVPKFASWGDGDDDEPRSDKGDAPPQPPPAPGSGAPGPARAAKPVSLRGGEEIPEPTLAEVKEEGELGGEE--EEEEEEEEGLDEAEGERPKKRGPKKRKMTKARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGKRPDLVSYVQTLCKGLSQPTTNLVAGCLQLNSRNFLTEQGADGAGRFHGSGGPFAMHPYPYPCSRLAGAQCQAAGGLGGGAAHALRTHGYCAAYETLYAAAGGGGASPDYNSSEYEGPLSPPLCLNGNFSLKQDS--SPDHEKSYHYSMHYSALPGSRP-TGHGLVFGSSAVRGG-VHSENL-LSYDMHLHHDRGPMYEELNAFFHN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63689-1", "uniprot_id": "NDF2_RAT", "id": "Q63689-1", "name": "Neurogenic differentiation factor 2", "aln": "MLTRLFSEPGLLSDVPKFASWGDGDDDEPRSDKGDAPPQPPPAPGSGAPGPARATKPVSLRG-EEVPEPTLAEVKEEGELGGEE--EEEEEEEEGLDEAEGERPKKRGPKKRKMTKARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGKRPDLVSYVQTLCKGLSQPTTNLVAGCLQLNSRNFLTEQGADGAGRFHGSGGPFAMHPYPYPCSRLAGDQCQAAGGLGGGAAHALRTHGYCAAYETLYAAAGGGGASPDYNSSEYEGPLSPPLCLNGNFSLKQDS--SPDHEKSYHYSMHYSALPGSRP-AGHGLVFGSSAVRGG-VHSENL-LSYDMHLHHDRGPMYEELNAFFHN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W6C8-1", "uniprot_id": "NDF2_DANRE", "id": "Q9W6C8-1", "name": "Neurogenic differentiation factor 2", "aln": "MLTRLFKEPSLLPDMQKFGGWVDDSGSEDSKTKDEEQERCRLGDEDLDEG--------SVKG---------GGSRAQSEIAGEEDYDEDVDEDDCGEEGDGDRPKKRGPKKRKMTPARLERSKVRRQKANARERTRMHDLNSALDNLLKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRNGKRPDVVSYVQTLCKGLSQPTTNLVAGCLQLNSRNFLTEQCQEGV-RFHTPTPSFSIQSYPYQCSRLSSTNCQS-----GSSTHSLRNHSLCSAYEALYTEG----TSPEYISADFEGHHGPPVCVNGNFGVRQEEPLSPDAERGYQYSMHYTNLHGSRSSAAHGITCGPPGARSGSVHSENLPLFHDVHMHHDRTPAYEELNAFFHS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******.**.**.*: **..* *....* . *.: . * .::* . : :.*:.*** :*: :*:: :*.:*:************* *******:**********.******:***** *********************************.*****:********************************** :*. *** . .*:::.*** ****:. :**: *.::*:**.*. *:***:**: . :**:* *:::** .**:*:****.::*:. *** *:.*:*****: * ***. :.**:. *....*.* ****** * :*:*:**** * *********.", "identical_positions": 221, "similar_positions": 90, "identity": "56.67%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010625-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54838-1", "uniprot_id": "DUS5_RAT", "id": "O54838-1", "name": "Dual specificity protein phosphatase 5", "aln": "MKVTSLDGRRLRKMLRKEAEARCVVLDCRPYLAFAASSVRGSLNVNLNSVVLRRARGGAVSARYVLADEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLSAGPRVYFLKGGYETFYSQYPECCVDAKPISQEKLEGERGLLSQCGKPILSVAYRPAYDQGGPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACTTHLHYKWIPVEDSHTADISSHFQEAIDFIDCVREEGGKVLVHCEAGVSRSPTICMAYLMKTKQFRLKEAFEYIKQRRSVVSPNFGFMGQLLQYESEILPSTPTPQPPSCQGEAASSTFIGHLQTLSPDMQGAYCTFPTSVLAPVPTHATVAELHRSPVATATSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q1HL35-1", "uniprot_id": "Q1HL35_MOUSE", "id": "Q1HL35-1", "name": "Dual specificity protein phosphatase", "aln": "MKVTSLDGRQLRKMLRKEAEARCVVLDCRPYLAFAASSVRGSLNVNLNSVVLRRARGGAVSARYVLPDEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLPAGPRVYFLKGGYETFYSQYPECCVDVKPTSQEKIEGERSLLSQCGKPVLSVAYRPAYDQGGPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACTTHLHYKWIPVEDSHTADISSHFQEAIDFIDCVREEGGKVLVHCEAGVSRSPTICMAYLMKTKQFRLKEAFDYVKQRRSVVSPNFGFMGQLLQYESEILPSTPTLQPPSCQGEAASSTFIGHLQTLSPDMQGTYCTFRTSVLAPVPTHSTVPELHRSPVATATSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16690-1", "uniprot_id": "DUS5_HUMAN", "id": "Q16690-1", "name": "Dual specificity protein phosphatase 5", "aln": "MKVTSLDGRQLRKMLRKEAAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAVSARYVLPDEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLPAGPRVYFLKGGYETFYSEYPECCVDVKPISQEKIESERALISQCGKPVVNVSYRPAYDQGGPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPASVLAPVPTHSTVSELSRSPVATATSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PBT4-1", "uniprot_id": "Q6PBT4_DANRE", "id": "Q6PBT4-1", "name": "Dual specificity protein phosphatase", "aln": "MKVSSIDCRRLRKIIRKECGN-CLIVDCRPYFSFSNSCIRGSVNVNLNSVVVRRSRGGPVPLQFVIPDEKALFRLRE---GSISAVVALDDRTPHLQKLKKDSIAQIVIN-TLSHLTSSASICFLKGGYENFHAHYPELCTETRSVEVSEDKSERGVSSHCDK--LASHHKPDYDQGRPVEILPFLYLGSAYHACRQDYLSDLHITALLNVSRRDSRPARGQYNYKWIPVEDSHTADISSHFQEAIDFIERVKAEGGKVLVHCEAGISRSPTICMAYIMKTQRLRLEQAFDVIRQRRAIISPNFSFMGQLLQFESEVVSSTPPLVTPAAQ--ETPTFFSGDFTLETESFESSVFTFPTSFLTPIQPSFKLSPITALP-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*:* *:***::***. *:::*****::*: * :***:********:**:***.*. ::*:.** * ** : *.::***.**: : * ***:::* *::*:. *: *.:.. : *******.*::.*** *.:.:. . .: :.**.: *:*.* : ::* **** ****************.: ::*::************ *... : :*************************: *: :***********:**********:***:::**::**: ::***:::****.*******:***::.*** .*:.* : : : *.: : .::.: ** :*.*:*: . .:. : * ", "identical_positions": 193, "similar_positions": 118, "identity": "50.26%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010713-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70367-1", "uniprot_id": "CNMD_RAT", "id": "O70367-1", "name": "Leukocyte cell-derived chemotaxin 1", "aln": "MTENSDKVPITMVGPEDVEFCSPPAYATVTVKPSGSPTRLLKVGAVVLISGAVLLLFGAIGAFYFWKGNDNHIYNVHYTMSINGRLQDASMEIDAANNLETFKMGSGAEEAIEVNDFQNGITGIRFAGGEKCYIKAQVKARIPEVSTGTKQSIS-ELEGKIMPVKYEENSLIWVAVDQPVKDNSFLSSKILEFCGDLPIFWLKPMYPKEIPRERREVVRSSAPSTTRRPHSEPRGNAGPGRLSNRTRPSVQDDEEPFNPDNPYHQQEGE--SMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVVMPCSWWVARILGMV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1F6-1", "uniprot_id": "CNMD_MOUSE", "id": "Q9Z1F6-1", "name": "Leukocyte cell-derived chemotaxin 1", "aln": "MTENSDKVPITMVGPEDVEFCSPPAYTTVTVKPSGSPTRLLKVGAVVLISGAVLLLFGAIGAFYFWKGNDNHIYNVHYSMSINGKLQDGSMEIDAVNNLETFKMGSGAEEAIEVNDFKNGITGIRFAGGEKCYIKAQVKARIPEVGTVTKQSIS-ELEGKIMPANYEENSLIWVAVDQPVKDSSFLSSKILELCGDLPIFWLKPMYPKEIQRERREVVRNSAPSTTRRPHSEPRGNAGPGRLSNGTRPNVQDDAEPFNPDNPYHQQEGE--SMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVVMPCSWWVARILGMV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75829-1", "uniprot_id": "CNMD_HUMAN", "id": "O75829-1", "name": "Leukocyte cell-derived chemotaxin 1", "aln": "MTENSDKVPIALVGPDDVEFCSPPAYATLTVKPS-SPARLLKVGAVVLISGAVLLLFGAIGAFYFWKGSDSHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMGSGAEEAIAVNDFQNGITGIRFAGGEKCYIKAQVKARIPEVGAVTKQSISSKLEGKIMPVKYEENSLIWVAVDQPVKDNSFLSSKVLELCGDLPIFWLKPTYPKEIQRERREVVRKIVPTTTKRPHSGPRSNPGAGRLNNETRPSVQEDSQAFNPDNPYHQQEGE--SMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVIMPCSWWVARILGMV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P58239-1", "uniprot_id": "CNMD_DANRE", "id": "P58239-1", "name": "Leukocyte cell-derived chemotaxin 1", "aln": "MEETAEKTPVEAYS---------------TLKPK-GLMKMKKTALVAFIAGAALLLFGGVGAFYLWKVTEKEAISAHLGRNIDIKIENDS--------------DSAEGTIVEVQDFKAGITAVKFPGKEKCFIKSQARTELSEDEAGVKAEVA---------------SLVWITSEEPLKDSSFLSPEILRFCADLPIYWHHPANSRALRK------RRSATRMRRQTSAGVNRQPARRRNSTASARDERPTGPEYNPENPYHQNQGSEGTMVFDPMLDHRGICCTECHRSYTHCERVCEPLGGYWPWPYNYHGCRPVCRLIMPCRWWAARVLGLV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *.::*.*: . *:**. . :: *.. *.:*:**.*****.:****:** .:.. ..* .*: :::: * .*. : *:**: ***.::*.* ***:**:*.::.:.* : .* .:: **:*:: ::*:**.****.::*.:*.****:* :* .: : : * .. ::. : . :.. * .. : . : :**:*****::*. :*.*** ***.**** **:******:::*******:******:***..**::*** **.**:**:*", "identical_positions": 118, "similar_positions": 109, "identity": "35.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010716-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P78411-1", "uniprot_id": "IRX5_HUMAN", "id": "P78411-1", "name": "Iroquois-class homeodomain protein IRX-5", "aln": "MSYPQGYLYQPSASLALYSCPAYSTSVISGPRTDELGRSSSGSAFSPYAGSTAFTAPSPGYNSHLQYGADPAAAAAAAFSSYVGSPYDHTPGMAGSLGYHPYAAPLGSYPYGDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWTPRNRSEDEEEEENIDLEKNDEDEPQKPEDKGDPEGPEAGGAEQKAASG-CERLQGPPTPAGKETEGSLSDSDFKEPPSEGRLDALQGPPRTGGPSPAGPAAARLAEDPAPHYPAGAPAPGPHPAAGEVPPGPGGPSVIHSPPPPPPP--AVLAKPKLWSLAEIATSSDKVKDGGGGNEGSPCPPCPGPIAGQALGGSRASPAPAPSRSPSAQCPFPGGTVLSRPLYYTAPFYPGYTNYGSFGHLHGHPGPGPGPTTGPGSHFNGLNQTVLNRADALAKDPKMLRSQSQLDLCKDSPYELKKGMSDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JKQ4-1", "uniprot_id": "IRX5_MOUSE", "id": "Q9JKQ4-1", "name": "Iroquois-class homeodomain protein IRX-5", "aln": "MSYPQGYLYQPSASLALYSCPAYSTSVISGPRTDELGRSSSGSAFSPYAGSTAFTAPSPGYNSHLQYGADPAAAAAAAFS-YVGSPYDHTPGMAGSLGYHPYAAPLGSYPYGDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWTPRNRSEDEEEEENIDLEKNDEDEPQKPEDKGDLEGPESGGAEQKATAG-CERLQGPLSPAGKETEGSLSDSDFKESSSEGRHDELPRPPRAGESSPAGPATARLAEDAGPHYPASVPAPGPHPSAGELPPGSGGSSVIHSPPPPPPPPPAVLAKPKLWSLAEIATSSDKVKDGGGGSEGSPCPPCPGPMGGQTLGGSRASPAPAPARSPSAQCPFPGGTVLSRPLYYTAPFYPGYTNYGSFGHLHGHPGPGPSPTAGPGSHFNGLNQTVLNRADVLAKDPKMLRSQSQLDLCKDSPYELKKGMSDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q1LXU5-1", "uniprot_id": "IRX5A_DANRE", "id": "Q1LXU5-1", "name": "Iroquois homeobox protein 5a", "aln": "MAYPQGYLYQPSASLALYSCPAYSTSVISGPRTEELGRSSSGSAFAPYAGSTAFTSASPGYNSHLPYSAD--AAAAATFTSYVSSPYDHTTGMAGSIGYHPYAAPLGSYPYGDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWTPRNRSEDEEEDENIDLEKNDDDEPNKPTDKGDSTDTEADHKLINPGEIPCDRFKD--ETHSKDLDPPLTDSELKEA--EERTDLLAEQAKPTTSSPS--VLQRGSDLITQEKPS---EPGHAASTGNS----NVTSVIHSPPSAPKP--------KLWSLAEIATSSDRCK---GSSEAS-------QAAGLSQSTVIAS-AASPTRS-SPQCPLPNNTVLSRPIYYTSPFYPGYTNYSTFGHLHSSHGTNTSSTA----HFNGLSQTVLNRAEALVRESK-VRSQTQVDLCKDSPYELKKGMSNI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*******************************:***********:*********:.******** *.** *****:*: **.******.*****:*********************************************************************************************:*********:***:** **** ..*:. :. *:*::. . .*: : .*:**::**. * * * * .:. .**: . * :: . *: ** .::*: . .*******..* * *************: * *..*.* .* : . ** *.:*:** *.***:*..******:***:*********.:*****. *.....*: *****.*******:.*.::.* :***:*:***************:*", "identical_positions": 310, "similar_positions": 87, "identity": "63.79%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010716-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18424-1", "uniprot_id": "LCAT_RAT", "id": "P18424-1", "name": "Phosphatidylcholine-sterol acyltransferase", "aln": "-----------MGLPGSPWQWVLLLLGLLLPPATSFWLLNVLFPPHTTPKAELSNHTRPVILVPGCMGNRLEAKLDKP----------------NVVNWLCYRKTEDFFTIWLDFN----------MFLPLGVDCWIDNTRVVYNRSSGHMSNAPGVQIR-----------------VPGFGKTYSVEY----------------------------------------LDDNK---------------------LAG--YLHTLVQNLVNNGYVRDETVRAAPYDWRLA---PRQQDEYYQKLAGLVEEMYAAYG-KPVFLIGHSLGCLHVLHFLLRQPQS----------WKDHFIDGFISLGAPWGGSIKPMRILASGDNQGIPIMSNIKLREEQRITT------------TSPWMFP--AHHVWPEDHVFISTPNFN----------YTGQDFERFFADLHFEEGWHMFLQSR----------DLLAGLP--------------------------APGVEVYCLYGVGMPTAHTYIYDH---------NFPYKDPVAALYEDGDDTVATRSTELCGQWQGRQSQA------VHLLPMNG-------------TDHLNMVFSNKTLEHINAILLGAYRHGTPKSPTASLGPPTKE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16301-1", "uniprot_id": "LCAT_MOUSE", "id": "P16301-1", "name": "Phosphatidylcholine-sterol acyltransferase", "aln": "-----------MGLPGSPWQRVLLLLGLLLPPATPFWLLNVLFPPHTTPKAELSNHTRPVILVPGCLGNRLEAKLDKP----------------DVVNWMCYRKTEDFFTIWLDFN----------LFLPLGVDCWIDNTRIVYNHSSGRVSNAPGVQIR-----------------VPGFGKTESVEY----------------------------------------VDDNK---------------------LAG--YLHTLVQNLVNNGYVRDETVRAAPYDWRLA---PHQQDEYYKKLAGLVEEMYAAYG-KPVFLIGHSLGCLHVLHFLLRQPQS----------WKDHFIDGFISLGAPWGGSIKAMRILASGDNQGIPILSNIKLKEEQRITT------------TSPWMLP--APHVWPEDHVFISTPNFN----------YTVQDFERFFTDLHFEEGWHMFLQSR----------DLLERLP--------------------------APGVEVYCLYGVGRPTPHTYIYDH---------NFPYKDPVAALYEDGDDTVATRSTELCGQWQGRQSQP------VHLLPMNE-------------TDHLNMVFSNKTLEHINAILLGAYR--TPKSPAASPSPPPPE----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04180-1", "uniprot_id": "LCAT_HUMAN", "id": "P04180-1", "name": "Phosphatidylcholine-sterol acyltransferase", "aln": "-----------MGPPGSPWQWVTLLLGLLLPPAAPFWLLNVLFPPHTTPKAELSNHTRPVILVPGCLGNQLEAKLDKP----------------DVVNWMCYRKTEDFFTIWLDLN----------MFLPLGVDCWIDNTRVVYNRSSGLVSNAPGVQIR-----------------VPGFGKTYSVEY----------------------------------------LDSSK---------------------LAG--YLHTLVQNLVNNGYVRDETVRAAPYDWRLE---PGQQEEYYRKLAGLVEEMHAAYG-KPVFLIGHSLGCLHLLYFLLRQPQA----------WKDRFIDGFISLGAPWGGSIKPMLVLASGDNQGIPIMSSIKLKEEQRITT------------TSPWMFP--SRMAWPEDHVFISTPSFN----------YTGRDFQRFFADLHFEEGWYMWLQSR----------DLLAGLP--------------------------APGVEVYCLYGVGLPTPRTYIYDH---------GFPYTDPVGVLYEDGDDTVATRSTELCGLWQGRQPQP------VHLLPLHG-------------IQHLNMVFSNLTLEHINAILLGAYRQGPPASPTASPEPPPPE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P7R5-1", "uniprot_id": "A0A8M1P7R5_DANRE", "id": "A0A8M1P7R5-1", "name": "Phosphatidylcholine-sterol acyltransferase", "aln": "-----------MG-NSSLFRCVALFL-ILLHQTSGFWLFNVIFPPTAKPR-VINNSTPPLIIVPGNLGNRLEAKIDKP----------------TLVHWMCYKKSEDWFPLWIDLN----------MFMPIGVDCWIDNIRIVYNRTTRKTSNAPGVDVR-----------------VPGFGQTHPIEF----------------------------------------LDLNK---------------------LTG--YFHTMVQHLVSIGYVRNETVRGAPYDWRIA---PNEQEEYFSRLKNLVEEMHDEYK-QPVYLLGHSMGSNYILYFLNQQTQD----------WKDHYIKGFISLGAPWGGAVKPLRVLASGENDGIPFVSNIKIREEQRMTT------------TNPWMIP--SEETWPKDHTFISTPFFN----------YTNQDYMQFFKDINFEDGWYMWDDTR----------NLTAGLP--------------------------APGVEVYCLYGVGLPTPVTYIYDE---------QFPNADPIDILYDDGDDTVDSRSMSLCKRWIGKQEQA------VHVTEFRG-------------MPHLDMVFNHKSLTTVQRILEGTYREEKDVGFEQPSSIGFV-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7L9-1", "uniprot_id": "Q9I7L9_DROME", "id": "Q9I7L9-1", "name": "Group XV phospholipase A2", "aln": "-----------MRLKSGVLS--LLLLTTFLALGECFWPFSKWHGRNDNPSAPPEPKLSPVIFVPGDGGSQMDARLNKP----------------NSP-YLICQKTHDWYNLWLDLE----------QLVIPMVYCWIDNVKLYYDKVTRTTHNTPGVETR-----------------IPGWGNPEVVEW----------------------------------------IDPTK---------------------NSAGAYFKDIANELVKLGYIRKQNIHGAPYDFRKA---PNENQQFFIDLKQLVEDSYEANNQSAVTFISHSMGSLMTLVFLQEQTLQ----------WKAKYVKRMISLAGVWAGSFKAVKVFAMGDDLDSFALSAKILKAEQITHP------------STAWLLP--SPLFWKPSEVLAMTPSRN----------YTMAQLEEFFKDLDYMTGWEMRKDTI----------RYNRNFD--------------------------PPNVELHCLYGEGIDTVERLQYKK---------SDISGETPKLIMGLGDGTVNQRSLRACKYWAGYSKAP------INTLALQN-------------VDHLHILSNPDVLKYIRTVMQQP-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40345-1", "uniprot_id": "PDAT_YEAST", "id": "P40345-1", "name": "Phospholipid:diacylglycerol acyltransferase", "aln": "MGTLFRRNVQNQKSDSDENNKGGSVHNKRESRNHIHHQQGLGHKRRRGISGSAKRNERGKDFDRKRDGNGRKRWRDSRRLIFILGAFLGVLLPFSFGAYHVHNSDSDLFDNFVNFDSLKVYLDDWKDVLPQGISSFIDDIQAGNYSTSSLDDLSENFAVGKQLLRDYNIEAKHPVVMVPGVISTGIESWGVIGDDECDSSAHFRKRLWGSFYMLRTMVMDKVCWLKHVMLDPETGLDPPNFTLRAAQGFESTDYFIAGYWIWNKVFQNLGVIGYEPNK-MTSAAYDWRLAYLDLERRDRYFTKLKEQIELFHQLSG-EKVCLIGHSMGSQIIFYFMKWVEAEGPLYGNGGRGWVNEHIDSFINAAGTLLGAPKAVPALISGEMKDTIQLNTLAMYGLEKFFSRIERVKMLQTWGGIPSMLPKGEEVIWGDMKSSSEDALNNNTDTYGNFIRFERNTSDAFNKNLTMKDAINMTLSISPEWLQRRVHEQYSFGYSKNEEELRKNELHHKHWSNPMEVPLPEAPHMKIYCIYGVNNPTERAYVYKEEDDSSALNLTIDYESKQPVFLTEGDGTVPLVAHSMCHKWAQGASPYNPAGINVTIVEMKHQPDRFDIRGGAKSAEHVDILGSAELNDYILKIASGNGDLVEPRQLSNLSQWVSQMPFPM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . . . . . : *. . :. : .. * : ::::: .: : .:**: : : : .. :** .. .: :* . :. : : :.* ** .: : .*.**:* ..:.:: * :* : . * ::.**:*. : *: * ..:. :*. .. *: *.: : *: . :. : : . . ::* * . . * : * :: . * . .* ::::*:** . * *.. . : **.** : * * : :. *:.:: . : : ", "identical_positions": 44, "similar_positions": 119, "identity": "6.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010717-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ABF5-1", "uniprot_id": "D4ABF5_RAT", "id": "D4ABF5-1", "name": "", "aln": "MSDSPAG--SNPRTPESSGSGGS----GGGGKRPAVPAVVSLLPPADPLRQANRLPIRVLKMLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAAANGLGSEKDPSRSAPGAAS---AAAALKQLGDSPAED-KSSFKPYSKGSGGGDSRKDGGSSSVSSTT------SSSSSSPGDKAG-FRVPSAACPPFPPHGAAVSTSSNSSSPGGSRGGSPHHSDCKSGSGGAGGGGELDKKDQEAKPSPEPAAGSRGSSGDS-AHGGP---------------EATASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDP----------SKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHSASHLGGSSCSTCSAHDPAGPSLKASGYPLVYPG---HPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAA-SGPCDKRFATSEELLSHLRTHTALPGAE-KLLAAYPGASSLGSAAAAAAAAASCHLHLPPPAAPGS-PGSLSLRSPHTLGLSRYHPYGKSHLSTAGGLAVP---SLPTAGPYYSPYALYGQRLASASALGYQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0CL69-1", "uniprot_id": "ZN703_MOUSE", "id": "P0CL69-1", "name": "Zinc finger protein 703", "aln": "MSDSPAG--SNPRTPESSGSGGGSSSGGGGGKRPAVPAVVSLLPPADPLRQANRLPIRVLKMLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAAANGLGSEKDPSRSAPGAAS---AAAALKQLGDSPAED-KSSFKPYSKGSGGGDSRKDSGSSSVSSTT------SSSSSSPGDKAG-FRVPSAACPPFPPHGASVSTSSNSSSPGGSRGGSPHHSDCKNGGGGAG---ELDKKEQEAKPSPEPAAGSRGSGGDS-AHGGP---------------EATASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDP----------SKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHSASHLGGSSCSTCSAHDPTGPSLKASGYPLVYPG---HPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAA-SGPCDKRFATSEELLSHLRTHTALPGAE-KLLAAYPGASSLGSAAAAAAAAASCHLHLPPPAAPGS-PGSLSLRSPHTLGLSRYHPYGKSHLSTAGGLAVP---SLPTAGPYYSPYALYGQRLASASALGYQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H7S9-1", "uniprot_id": "ZN703_HUMAN", "id": "Q9H7S9-1", "name": "Zinc finger protein 703", "aln": "MSDSPAG--SNPRTPESSGSGSG-----GGGKRPAVPAAVSLLPPADPLRQANRLPIRVLKMLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAAN-GLGAEKDPGRSAPGAAS---AAAALKQLGDSPAED-KSSFKPYSKGSGGGDSRKDSGSSSVSSTS------SSSSSSPGDKAG-FRVPSAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGVGG--GELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGA---------------ESGASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDP----------SKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAGPSLKAGGYPLVYPG---HPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAA-SGPCDKRFATSEELLSHLRTHTALPGAE-KLLAAYPGASGLGSAAAAAAAAASCHLHLPPPAAPGS-PGSLSLRNPHTLGLSRYHPYGKSHLSTAGGLAVP---SLPTAGPYYSPYALYGQRLASASALGYQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90ZE2-1", "uniprot_id": "ZN703_DANRE", "id": "Q90ZE2-1", "name": "Zinc finger protein 703", "aln": "MSELPPGFAVSPRNQQTFKSHYITNDSSPTCLGLQVDSIAS-LPYRDPARQEKRLPIRILKMLTAHTSHILHPEYLQPLSSAPVS-IELDAKKSPLALLAQTCSQIGKPDPPPSSKLGSLSSSSHGDKDSRSSSSSLKSGEHQNLDDKSSFKPYSKTGSECRKEGAGINSSADKAGFRVPNGSSSSVTCTSLPPHAPSPRASSPQQTSGQSHTHRQSQSPLSQKTAHLQTTHMDSKAAGSDPGNDSSSSGSDRNGKKD--SDHNKSSLDVVQIANSSHARASVNSSSASSSSS---------------PQPDSKTDSQPPQPSLGTGHIAPVSPFKPGHSVFPLPSSTMGYHGSIVGAYTGYPSQFVPGLDP----------AKS-------SLGMGVP-GKHPSSSPLTGASPPSFMQGLCRDPYCLT-YPNAPHLGGSNCSSC-VHDPS--SALKSGFPLMYPTHHLHSLHPSSLSSSATSSLS--HPLYTYGFMLPNETLPHACNWVSV-GGPCDKRFATSEELLAHLRTHTALPGVDGKLLSGYP---------SSVSSAASCHLHLPPPSSPGALPSSLSLRGSPGLGLARYHPYGKAHLPGAPSLPMH---SLPATAPYYSPYALYSQRLGSASALGYQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJS8-3", "uniprot_id": "ELBOW_DROME", "id": "Q9VJS8-3", "name": "Zinc finger protein Elbow", "aln": "-------------------------------------------------------------MLQSSNHHYLRPDYMT---AAAAPTAQLDNKSSPLALLAQTCSAIGADTTNPK-LLAANIEKSTKQLQHHPKGSSGSGGSGS---FGLSQQASMDGSARDKSSPVSSHSSSVSTGSVEQQQLPPAHGSSSSSKPTPTTFKPYEPNNNISNITTAADCGATNLSSNNTSAQQRVKTPKSMTNGGGQRCDSNQSASSQHRESPTAAGSLRRTPTSGLAGGVMQHNGSPGLPPTASTTPGRSNSKESAAMHSPSAAAAAAAAAAQIASSNRLQEAALAAAKEANYVKALHAASQQGSASAAAAAASYYPPGYGSPYSMDLMTASSLMSPHHAMFKASAMNPYLNYARMKGLTEQSMMAATPNVCRDPYCTGCPASPHYINKAAGQPCPAGCPQCEGGGGGGGGSSKSSGSQGGSGGSSSAAAAAAAAAASSYHAQLAALAAASQMPYVCSWIGSDAAYCGKRFGTSDDLFQHLRTHTASVPDAVLSAAAAGGIPPN--------HPLFQRTYPTPPLSPLS----AARYHPYGKPS--MLPPSLAPPGMPGLP------PHPALAQYFAPYSLYGPRMGSSHP----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q24423-1", "uniprot_id": "NOC_DROME", "id": "Q24423-1", "name": "Zinc finger protein Noc", "aln": "----------------------------------------------------MVVLEGGGGVVTIGNNQYLQPDYLA---PLPT---TMDAKKSPLALLAQTCSQIGADSSAVKPLLAMDKNKTKPGACSSSSNSSSSSGSAE---ISAAKSPSGQAKSPKSSTPISSTATSASLSNTSTGEIKLAFKPYETNVLSHQNQNSFKSSSSLDAEPTRPSS--KNSSSAQERVPSRSKSNATPTDGGKAEISAHDSSSSRKTVSPSGSSQRGASPIVRSGMEVLNNANGTAQHP-----------KEMSSMAAAAAAAAAAYKAAGPYGLNPLSALCCPPGMEQHANPAFRPPFAGGFSHHHAAMLAVAANGG-------------YPGGAPGGGPAGQPNPYISYQRIKTPAGG---EAIVPVCKDPYCQGCPYSAHTQQMLMGAPCPAGCTQCEHQKYG-----LAMASAAGLPPAHPYSQAAAAAAAN--------AAAARSAPYVCSWVVG-DAYCGKRFQTSDELFSHLRTHTGNLSDPAAAAAALAQSQAQSLLGTLFPPSALRAGYPTPPLSPMSAAAAAARYHPYAKPPPGALAGGPSPFGAAGAFNPAAAAAAAALGPYYSPYAMYGQRMGAAHQ----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . : *:*:*: . .. :* *.*********** ** . . * : . . * . : . . : . :.. . : . .. . .. *. . . . . . . . : : . : .. . . . :. : * . * . . : :*:**** .. .* . . . . : : *: : *: *.*: . *.*** **::*: ******. :. . : .** :* : : . . . : . . .: . *::**::*. *:.:: ", "identical_positions": 54, "similar_positions": 106, "identity": "8.37%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010724-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYB8-1", "uniprot_id": "GO45_RAT", "id": "Q6AYB8-1", "name": "Golgin-45", "aln": "MEKMTTLKSFESKGILTSTPIRGAGDGMETEEPPKSVEVTHGVQPINQHVLPSPRKK-------------------VPSDSPGVLQLG---KILNEKTVEVEAVRIFVPKAAITHDIPT-KSAKVKSLGHHREELHNQSEVVTDP-----------------------------------------------RKELSEVKKVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDPQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNFRVVLQHQNRDAQSAIQDLLSEREQFRQEMISTQKFLEELLVSLQWGREQTYSPNTQPHSTADLALTNHRLAEAVHAHLLGNVGISHPKRTPATAEVCSTPAEKMAEKVLRILDPVACTESSPDNAFAES---TLLTTKKNIGRFHPYTRYENITFNCCSHCQGELLAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2X8-1", "uniprot_id": "GO45_MOUSE", "id": "Q8R2X8-1", "name": "Golgin-45", "aln": "MEKMTTLKSSENKGILTSTPIRGAGDGMETEEPPKSVEVTHGVQPINQHVLPSPRKK-------------------VSSDSPGVLQLG---KILNERTVEVEAVRIFVPKAAITHDIPT-KNTKVKSLGHHREELHNQAEVVTDP-----------------------------------------------RKELSEVKKVLEKLKNSERRLLQDKEGLSNQLRVQTEINRELKKLLVASVGDDPQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNFRVVLQRQNRDAQSAIQDLLSEREQFRQEMTSTQKFLEELLVSLQWGREQTYSPNTQPHSTADLALTNHGLAQAIHAHLLGNVGISHQKKIPTTVEFCSTPAEKMAEKVLRILDPVACTESSPDNQFAESSPTTLLTTKKNIGRFHPYTRYENITFNCCNHCQGELIAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2G9-1", "uniprot_id": "GO45_HUMAN", "id": "Q9H2G9-1", "name": "Golgin-45", "aln": "----MTTKNLETKVTVTSSPIRGAGDGMETEEPPKSVEVTSGVQSRKHHSLQSPWKKA------------------VPSESPGVLQLG---KMLTEKAMEVKAVRILVPKAAITHDIPN-KNTKVKSLGHHKGEFLGQSEGVIEP-----------------------------------------------NKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEELLVSLQWGREQTYSPSVQPHSTAELALTNHKLAKAVNSHLLGNVGINNQKKIPSTVEFCSTPAEKMAETVLRILDPVTCKESSPDNPFFESSPTTLLATKKNIGRFHPYTRYENITFNCCNHCRGELIAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8JM41-1", "uniprot_id": "B8JM41_DANRE", "id": "B8JM41-1", "name": "", "aln": "---MMSAELIIKD--VSVVAVRGPGDGMETDKPLPAPEQLT-EAPLQKICSPKHSPR-------------------VATGSPGVLHLG---KVSRDACLELEAVRIVVPRAAIIRTGRSGAHTDDRGSPQHGDEPPPAPPSPPPP-----------------------------------------------AEPLQEYKNSLEKLQSSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLAREKNHLILENETLCRNLSHTAEQLERMSIQCDVWRSKFLASRVMAEELTNARSALQRQTRDAQCAIQDLLSEREEFSRDMTHTHRCLEQLLVSLQWGRQQTYYPSAKPLSTGELATANHKLADAINAHLLGKLENSGGKKSPST-EICNTPAEKMAEKVLRSLDPVCVSEQEHDASSSDS---PFLPNRKSIGRFHPYTRYENITFNCCERCHGEIIVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHE3-1", "uniprot_id": "Q9VHE3_DROME", "id": "Q9VHE3-1", "name": "Golgin-45", "aln": "----MEANESAMPGTDKSQACRTSGDGMEQPENSGAAKTESEIPASADVDNKVKRPQLSRKDSSVVQEAVMGRKTSTSSGHSSNLPLPGLHTLYRRPENVTRSLAPVVPKGELVQMRPRLVTSADSLPEHKKTKAPKFVPYEPYPGAVNPMISEPTNKHKIHRDKNNLDIAVLVDQVSTLRTQELETETTDIKETDTASSHEVNSLKEELAKMRDERNYFQAQYKFQTQVNSELKSLLVASVGEDLQTRVNLLTEDKLQLARALLDTANNLTTHTEQIEFLAGQCEVWRSKFLASSVMVEELARWKADLTQKNQLLNESTKQLLHATHQIREIQLDMLKQLKFLAKIRFLN-----LPATDVISLSAENLN-------ILQRMVLHTGVGIPEETLKLSSASTSPLCEAEKYAVRALEFISQPLMATDEA--------IRALFDQAQRPHYVQSPASEVTPACDNQQLDKMQ-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . * .***** : : : . . : ..: .. * * .: .:: .**:. : : : :: : * : .: ::.*:.. :: :::: :. * :.**::* ***.*******:* * :.: *:.:* :* .* : :**:* :: **:********* **.:**:. : * ::.: : : ::** .:: . : *: * . * .. * . : ::: : . :. . ..:* : : .:* *: : * : . .. * * . . .*.. : : : ", "identical_positions": 64, "similar_positions": 119, "identity": "13.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010724-10", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29320-1", "uniprot_id": "EPHA3_HUMAN", "id": "P29320-1", "name": "Ephrin type-A receptor 3", "aln": "MDCQLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESSQVVMIAISAAVAIILLTVVIYVLIGRFCGY-KSKHGADEKRLHFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIISSIKALETQSKNGPVPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29319-1", "uniprot_id": "EPHA3_MOUSE", "id": "P29319-1", "name": "Ephrin type-A receptor 3", "aln": "MDCHLSILVLLGCCVLSCSGELSPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDD-HGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCTCNAGYEERGFICQACRPGFYKASDGAAKCAKCPPHSSTQEDGSMNCRCENNYFRAEKDPPSMACARPPSAPRNVISNINETSVILDWSWPLDTGGRKDITFNIICKKCGWNVRQCEPCSPNVRFLPRQLGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQYAAVSITTNQAAPSPVMTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYQKQEQETSYTILRARGTNVTISSLKPDTTYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGENSHVVMIAISAAVAIIVLTVVTYVLVGRFCGYHKSKHSAEEKRLHFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPEMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAMSYRKFTSASDVWSYGIVLWEVMSYGERPYSQMSNQDVIKAVDERYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDIATFHTTGDWLNGMRTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIISTIKALETQSKNGPVPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB13A7P7-1", "uniprot_id": "A0AB13A7P7_DANRE", "id": "A0AB13A7P7-1", "name": "receptor protein-tyrosine kinase", "aln": "MDCKTLILFLFFFTLIS-SADFIIHPSNEVNLLDSKASQGELGWISSPSHGWEEISGVDEHYTPIRTFQVCNVMEYSQNNWLRTNWIPRNSAQKIYVELKFTLRDCNSIPMVL-TCKETFNLHYLETEEDQGNKFREHQFSKIDTIAADESFTQMDLGDRILKLNTEVREVGPMTKKGFYLAFQDVGACVALVSVRVYFKKCPFTVRNLAMFPDTVPTDSQSLVEVRGSCVNNSKEEDPPKMYCSTEGEWLVPIGKCLCNIGYEERGVACQACRPGFYKASSGNVKCSKCPPHSYTHQEGSVHCGCEKNYFRADEDPASMACSRPPSAPRNVISAINETSVILDWNWPADNGGRKDVIFNVVCKRCWPGPRQCEPCRGAVRFLPRAFGLTNTTVTVADLLAHTNYTFEIEAQNGVSFQAPTIRQYAAVTITTNQAAPSAVTVIRKDRTSRNSISLSWMEPERPNGIILDYEVKYYEKQEQETSYTILRSKGTNVTLNGLKPDTTYLLQIRARTAAGYGSSSRKFEFETSPDSFSISSENSQVVLIAISSAVAIILLTVVLYIVISRFCRYSKSKH-PDEKRLPFGNGHLRLPGIKTYVDPHTYEDPSQAVHEFAKELDASSIAIDKVVGAGEFGEVCSGRLKLPSKKEICVAIKTLKAGYTEKQRRDFLSEASIMGQFDHPNIIRLEGVVTRSKPVMIVTEYMENGSLDGFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMECPATLYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPSSLKITASTASRPVNLLLDRNSTDITSFHTMGDWLESARTLPCKDAFSGVSYSSCDTLAKTSAEDFKKVGVTIVGPQKKIVSSLTTLETHSKNGPVPV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***: **.*: ::. .:: :***********: ******** ********************:******::**********:***********************:** ********:*:*::: :* *******:**************************:*****:.*******************************:********** **********************:**************** ** ******. *********** .* **:****** *:::**::* **:*****::**.****:****:****** **********.** *.*****: **::**:* . :***** ****** :*********:************:* **** :.. **:***:*********.* .*:************* ***:*************:************::*****:..***** *::***********:.****************.*.*:**:****:*****:**** *:::.*** * **** .:**** ******:***::***********:************:.*:**************************.*******.***********.*********************:*** *************.********************************************:*************************************:***::**************************** :************ *******:***:*********************************.**** :*:*:** *****:...**::*:* ****:. * **: *:**.******:** *::*:******:*******:*::.:***:********", "identical_positions": 797, "similar_positions": 130, "identity": "81.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010724-11", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K4R1-1", "uniprot_id": "A0A0G2K4R1_RAT", "id": "A0A0G2K4R1-1", "name": "Protein phosphatase 1 regulatory subunit", "aln": "MSGEDGPA---------AGPGAAAAAAAARERRQEQLRQWGARAGADPGPGERRAR---TVRFERAAEFLAACAGGDLDEARLMLRAADPGPGSGAATDPAVPPPARAVLDSTNADGISALHQACIDENLEVVRFLVEQGATVNQADNEGWTPLHVAASCGYLDIARYLLSHGANIAAVNSDGDLPLDLAESD---AMEGLLKAEITRRGVDVEAAKRAEEELLLHDTRCWLN-GGAMPEARHPRTGASALHVAAAKGYIEVMRLLLQAGYDTELRDGDGWTPLHAAAHWGVEDACRLLAEHGGGMDSLTHAGQRPCDLADEDVMNLLEELAQKQEDLR-------------------------------------NQKEASQGRGQESQVPSNSKHRRSSVCRLSS--------------------------------REKISLQDLSKERRPGGAGGLPIGDEDEGEEALAEHPAVEPRALNGVSSPA-----------------SSSPKSPVPPEEAPFSRRFGLQKTGSSGALGPSERKGTEGVLG----LQRSASSSVIEKASTQAREPRLARITPTPAQKVPEPFTLSEAAA-PPS-DHSAPPSRT-EPGSPVKPNVLTASAAPLADSRDR---DRRRSYQMPVRDEESESQRKARSRLMRQSRRSTQGVTLTDLKEAEKVAGK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPEPEQPALPSLDPSRRPRVPGVENA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EGPAQRAEAPEGQGQGPQAAREHRKAGHERRGPAEGEEAVPAERSP----------------ECSTVDGGSTVRRQRSQRD--------------LILESKQQHEEPDGGFRKLYTELRRENERLREALTETTLRLAQLKVELERATQRQERFAERPALLELERFERRALERKAAELEEELKALSDLRADNQRLKDENAALIRVISKLSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UMT1-1", "uniprot_id": "PP12C_MOUSE", "id": "Q3UMT1-1", "name": "Protein phosphatase 1 regulatory subunit 12C", "aln": "MSGEDGPA---------AGPGAAAAAAAARERRQEQLRQWGARAGADPGPGERRAR---TVRFERAAEFLAACAGGDLDEARLMLRAADPGPGSGAASDPAVPPPARAVLDSTNADGISALHQACIDENLEVVRFLVEQGATVNQADNEGWTPLHVAASCGYLDIARYLLSHGANIAAVNSDGDLPLDLAESD---AMEGLLKAEITRRGVDVEAAKRAEEELLLHDTRCWLN-GGAMPEARHPRTGASALHVAAAKGYIEVMRLLLQAGYDTELRDGDGWTPLHAAAHWGVEDACRLLAEHGGGMDSLTHAGQRPCDLADEDVMNLLEELAQKQEDLR-------------------------------------NQKEGSQGRGQESQVPSSSKHRRSSVCRLSS--------------------------------REKISLQDLSKERRPGGAGGPPIGDEDEGGEASAEHPAVEPRALNGVSSPV-----------------SSNPKSPVLPEEAPFSRRFGLQKTGSTGALGPSERRATEGVLG----LQRSASSSLLEKASTQAREPRLARITPTPAQKVPEPFTLYEAAT-PPSLDHSVPPSRR-EPGSIVKPNVLTASAAPLADSRD-----RRRSYQMPVRDEESESQRKARSRLMRQSRRSTQGVTLTDLKEAEKVAGK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPEPEQPALPSLDPSRRPRVPGVENA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EGPAQR-EAPEGQGQGPQAAREHRKAGHERRGPAEGEEAGPAERSP----------------ECSTVDGGSQVRRQHSQRD--------------LVLESKQEHEEPDGGFRKMYTELRRENERLREALTETTLRLAQLKVELERATQRQERFAERPALLELERFERRALERKAAELEEELKALSDLRADNQRLKDENAALIRVISKLSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZL4-1", "uniprot_id": "PP12C_HUMAN", "id": "Q9BZL4-1", "name": "Protein phosphatase 1 regulatory subunit 12C", "aln": "MSGEDGPA---------AGPG--AAAAAARERRREQLRQWGARAGAEPGPGERRAR---TVRFERAAEFLAACAGGDLDEARLMLRAADPGP--GAELDPAAPPPARAVLDSTNADGISALHQACIDENLEVVRFLVEQGATVNQADNEGWTPLHVAASCGYLDIARYLLSHGANIAAVNSDGDLPLDLAESD---AMEGLLKAEIARRGVDVEAAKRAEEELLLHDTRCWLN-GGAMPEARHPRTGASALHVAAAKGYIEVMRLLLQAGYDPELRDGDGWTPLHAAAHWGVEDACRLLAEHGGGMDSLTHAGQRPCDLADEEVLSLLEELARKQEDLR-------------------------------------NQKEASQSRGQEPQAPSSSKHRRSSVCRLSS--------------------------------REKISLQDLSKERRPGGAGGPPIQDEDEGEEGPTEPPPAEPRTLNGVSSPP-----------------HPSPKSPVQLEEAPFSRRFGLLKTGSSGALGPPERRTAEGAPGAG--LQRSASSSWLEGTSTQAKELRLARITPTPSPKLPEPSVLSEVTKPPPCLENSSPPSRIPEPESPAKPNVPTASTAPPADSRD-----RRRSYQMPVRDEESESQRKARSRLMRQSRRSTQGVTLTDLKEAEKAAGK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APESEKPAQ-SLDPSRRPRVPGVENS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DSPAQRAEAPDGQGPGPQAAREHRKVGKEWRGPAEGEEAEPADRSQ----------------ESSTLEGGPSARRQRWQRD--------------LNPEPEPESEEPDGGFRTLYAELRRENERLREALTETTLRLAQLKVELERATQRQERFAERPALLELERFERRALERKAAELEEELKALSDLRADNQRLKDENAALIRVISKLSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BDL9-1", "uniprot_id": "A0A8M2BDL9_DANRE", "id": "A0A8M2BDL9-1", "name": "Protein phosphatase 1 regulatory subunit 12C", "aln": "-MGDAAVAKRREQLTRWSGSSTDKEPAVPRSRWRGETSTR-APDGGRPDTNERQKKNRWRVTFEKTAEFLAVCASGDTEEAKAMLREVLLNE-------------EDDVVNCANADGITALHQACIDGSMEMVDFLLSHGANVNQVDSEGWTPLHVAASCGNLEIAEFLLQHGASLCSVNCDGDVPLDIAKDE---DTQMLLQKHILKQGMDLEAAKRAEEEWIMHDARHWLT-DGLPANLCQPRTGATPLHVAAAKGYLEAIKLLCQCGLDVSAKDCDGWTPLHAAAHWGQSDACRLLAEQLCDMEAHSNRGQSPFDVADESVASLLEELSKRQANWR-------------------------------------TEQQNSQ----TSNVNPANKKRRSSVCRMSS--------------------------------KDKISVQDQSKER--GVSGELELSDERESSPESS-----------TVSSPE-----------------STVPSS------------------------GTTEEKEVK--------------------ANDQDRASRTAVVPPTPQKRE-------------------------------------SPAESPSNTSGD------GRKYQAPVRDEESEFQRKARSRLMRQSRRSTQGVTLTDLKEAERSIVK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DNEPQHVSVQPVSPN-VTVTPAERDT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DPERESLEAQTKLG-----VRDRRKGRKERRSTG------VVQLAE----------------ENDDMDANEDAQQDNNARD--------------HQLDDSIHS---SLDYRKLYLRVLQENGNLKEKLQETQLQLNESKVQLEKLKQNQENGSDRPALLELERYEKKLLQRRAFELEDELKVLVDLRADNQRLKDENAALIRVISKLSK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9NEB2-1", "uniprot_id": "M9NEB2_DROME", "id": "M9NEB2-1", "name": "Protein phosphatase 1 regulatory subunit 12B", "aln": "------------------MSSLDARNNSAMMKRAEQLKRWEESDTNRAAPTPRHEHG-RRIKFSSGCVFLAACLSGDKDEVVQLLDQG-------------------ADINTANVDGLTALHQACIDDNLDMVEFLVERGADINRQDNEGWTPLHATASCGFVSIARYLVENGADVAAVNSDGDLALDLAIDVQHMAMIDYMEKMVQELNINVDEARKAEELAMLNDAKKWLRSDAAEVDRPHPKTGATALHVAAAKGYTKVLGLLLAGRGNVDRQDNDGWTPLHAASHWGQRETAEMLVESLADMDIRNYAGQSCIDVADRKIVKFLEELRANKRNKRRPSSQIRISDAMENHVEKTPTKLVRVEVRTDATKDAENVKPNQQIHAVEHPVEEEAPWRRKLPRTPSDSPTNNQVPDRELGTNSSETANDVILRRTQSFENDQKFYQKYNELRARIKANSCPILPANANANAAAANKSNNNNNLSSNNYHNNNNNNNKSDLLLGYAAGTTTTTSTPTTTTTTTSSTFNNTHSNTNNTSTTQQQPAAAAAASAANQLYSVQRSASLKDNSMYYRKPTVTIATSTAATAINSPSTTVQTPPIRSQVTAKIAEKSNNGSSSTASVSDAESSKPPPKQSASNMIKNFFKSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEELVKKKNMGMANNNNNNNISTTTTNTISNSGNETSSASSTSAPTPSILGSNEQQDELQPPPPPTTPPPAVIPTTTTATDETEIEEVVSSPPAGQSQNDTTASFTLSAPVRRSLSTEGEADANSDPEGDQDQTVVSASYTIMPRRERLPESSENVESIRSPQKTEPVAKSSSEDKSEEPPHARPTDLPLIPAPAAPSTEAIKSSSAATTPAALESPVRLRDKRGLSGSQESETKSDTASPVSSHPDFNARDSLLSLYARRTTDSSAGGGGVGGGAGVGAGGASGAATSSSTSAAERRPSWRLKFDAGSKFKLEDITSGGTYPPNNSTIIPSAPAVMAAANLSTTTGVQRRISSGPIALNASNQSLNSVGRPVSAPSEGTNNSAYVTPSARKFETNATSTGATTAATTTSNSTSNSVSATSANHTTATAPNATSNHDDKDNDKENDNRTQTVIQRRRKPKRRSTGVVHIDMDELDPERQNESSNNDNEEKEKESGSERTSRSRLGSTASTATTSESKSSSSNDKTENGDGIDYKALWEAEKLENDKLRQMLKQKDDEAVQTRATLERFANATTKNSLSELEKRERRAMERKLSELEEELKQLDAYKSDNHRLKEENAALIRVISKLSK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . : : . . *: : : *. . ***.* .** :*. :* :: :*.**::******** .:::* **:.:** :*: *.*******.:**** :.**.:*:.:**.:.:**.***:.**:* . :: : . .:::: *::*** :::*:: ** .. : :*:***:.********* :.: ** : . :* *********:*** ::..:*.* .*: . ** *:**..: .:**** .: : * . : .* . **. *. .:: *. .: * :. : . : . . ..* . :. . . : : ..*. .: .* * . :.: ******** ****::: :*::********* ::*.**. * . : .:... . .*. :: : * . ::. * .: . : * . : :.. * . . . . * : . : .: * : : : *: . :. . : : :* ***: *:: ::*: ***:*** * ::**:***:**************", "identical_positions": 176, "similar_positions": 204, "identity": "13.42%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010724-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O75396-1", "uniprot_id": "SC22B_HUMAN", "id": "O75396-1", "name": "Vesicle-trafficking protein SEC22b", "aln": "MVLLTMIARVADGLPLAASMQEDEQ--SGRDLQQYQSQAKQLFRKLNEQSPTRCTLEAGAMTFHYIIEQGVCYLVLCEAAFPKKLAFAYLEDLHSEFDEQHGKKVPT-VSRPYSFIEFDTFIQKTKKLYIDSRARRNLGSINTELQDVQRIMVANIEEVLQRGEALSALDSKANNLSSLSKKYRQDAKYLNMRSTYAKLAAVAVFFIMLIVYVRFWWL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZV15-1", "uniprot_id": "S22BA_DANRE", "id": "Q7ZV15-1", "name": "Vesicle-trafficking protein SEC22b-A", "aln": "MVLQTMIVRVADSLPLAASMQEDEQ--SGRDLQKYQSQAKQLCRKLNEQSPARCTLEAGKMCFHYVIEKGVCYLALCEAGFPKKLAFAYLEDLEGEFSEQYGAKVPS-VSRPYSFIEFDTYIQKTIKSYIDSRARRNLGNINSELHDVQRIMVANIEEVLQRGEALSALDSKASNLSSLSKKYRSDAKYLNTRSTYAKVAAGAVIIITLIIYVRFWWL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PGI6-1", "uniprot_id": "M9PGI6_DROME", "id": "M9PGI6-1", "name": "", "aln": "MALLTMIARVIDGLPLVGTMQDDEQVPSGRSILDYQNQAKMLFRKLGTHSPARCSIETGPYLFHYLIENDVCYLVMVDKMYSKRLAFNYLEDLAQEFHANYGRRVNS-VTRPYAFIEFDVYIQKAKKQLTDR--RRNISNINTQLQDVQRIMVQNIDDVLQRGTVLAELDTKTQNLSMMSQKYKKDAKLLNRKSMYVKAMALGMILLVFIMY--FWVL-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22214-1", "uniprot_id": "SEC22_YEAST", "id": "P22214-1", "name": "Protein transport protein SEC22", "aln": "-MIKSTLIYREDGLPLCTSVDNEND----PSLFEQKQKVKIVVSRLTPQSATEATLESGSFEIHYLKKSMVYYFVICESGYPRNLAFSYLNDIAQEFEHSFANEYPKPTVRPYQFVNFDNFLQMTKKSYSDKKVQDNLDQLNQELVGVKQIMSKNIEDLLYRGDSLDKMSDMSSSLKETSKRYRKSAQKINFDLLISQYAPIVIVAFFFVFLFWWIFLK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : *.*** ::::::: .: . :.:.* : :* :*.:..::*:* :**: :. * *:.: : :.:.*** **:*: ** ... . . . *** *::** ::* : * * : *:..:* :* .*::** **:::* ** * :. :..*. *::*:..*: :* : . :. : ::. : * ", "identical_positions": 48, "similar_positions": 87, "identity": "21.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010724-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P25189-1", "uniprot_id": "MYP0_HUMAN", "id": "P25189-1", "name": "Myelin protein P0", "aln": "MAPGAPSSSPSPILAVLLFSSLVLSPAQAIVVYTDREVHGAVGSRVTLHCSFWSSEWVSDDISFTWRYQPEGGRDAISIFHYAKGQPYIDEVGTFKERIQWVGDPRWKDGSIVIHNLDYSDNGTFTCDVKNPPDIVGKTSQVTLYVFEKVPTRYGVVLGAVIGGVLGVVLLLLLLFYVVRYCWLRRQAALQRRLSAMEKGKLHKPGKDASKRGRQTPVLYAMLDHSRSTKAVSEKKAKGLGESRKDKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P27573-1", "uniprot_id": "MYP0_MOUSE", "id": "P27573-1", "name": "Myelin protein P0", "aln": "MAPGAPSSSPSPILAALLFSSLVLSPALAIVVYTDREIYGAVGSQVTLHCSFWSSEWVSDDISFTWRYQPEGGRDAISIFHYAKGQPYIDEVGAFKERIQWVGDPRWKDGSIVIHNLDYSDNGTFTCDVKNPPDIVGKTSQVTLYVFEKVPTRYGVVLGAVIGGILGVVLLLLLLFYLIRYCWLRRQAALQRRLSAMEKGRFHKSSKDSSKRGRQTPVLYAMLDHSRSTKAASEKKSKGLGESRKDKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2R8QN30-1", "uniprot_id": "A0A2R8QN30_DANRE", "id": "A0A2R8QN30-1", "name": "", "aln": "------MLSVLALTSVVLLG--IASQSTALVVNTDSEKHALVGSDVRLSCSFFSWQWTSPEVSFTWHYRPDGAKDAISIFHYGGGEAYPANKGPFQNRLEFVGNPSRRDGSILIKNLDFGDNGTFTCDAKNPPDIGGHPSTIRLLVFEKVPVQAGVITGSIIGVVLGLLILVVAIYYLMRFLVARRVFSLS--MSKHGK-------KGKGKEGSQQKQASAVTDPAKLKAAASEKKKQ---ESRREKK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: :.:*:. : * : *:** ** * :. *** * * ***:* :*.* ::****:*:*:*.:********. *:.* : *.*::*:::**:* :****:*:***:.********.****** *:.* : * ******.: **: *::** :**:::*:: ::*::*: ** :*. :* * *. .*.* * *: * :: . *.**** : ***::**", "identical_positions": 105, "similar_positions": 72, "identity": "42.34%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010724-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P14408-1", "uniprot_id": "FUMH_RAT", "id": "P14408-1", "name": "Fumarate hydratase, mitochondrial", "aln": "MNRAFCLLAR-SRRFPRVPSAGAVLS---GEAATLPRCAPNVVRMASQNSFRIEYDTFGELKVPTDKYYGAQTVRSTMNFKIGGATERMPIPVIKAFGILKRAAAEVNQEYG-LDPKIASAIMKAADEVAEGKLNDH--FPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKKPVHPNDHVNKSQSSNDTFPTAMHIAAALEVHQVLLPGLQKLHDALSAKSKEFAQVIKIGRTHTQDAVPLTLGQEFSGYVQQVQYAMERIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLGPK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97807-1", "uniprot_id": "FUMH_MOUSE", "id": "P97807-1", "name": "Fumarate hydratase, mitochondrial", "aln": "MYRALRLLAR-SRRLLRVPSAGAAVS---GEATTLPRCAPNVARMASQNSFRVEFDTFGELKVPTDKYYGAQTVRSTMNFKIGGATERMPIPVIQAFGILKRAAAEVNQEYG-LDPKIASAIMKAADEVAEGKLNDH--FPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKKPVHPNDHVNKSQSSNDTFPTAMHIAAAVEVHKVLLPGLQKLHDALSAKSKEFAQVIKIGRTHTQDAVPLTLGQEFSGYVQQVQYAMVRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALVELSGAMNTAACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDASVSFTDNCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLGPK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07954-1", "uniprot_id": "FUMH_HUMAN", "id": "P07954-1", "name": "Fumarate hydratase, mitochondrial", "aln": "MYRALRLLAR-SRPLVRAPAAALASAPGLGGAAVPSFWPPNAARMASQNSFRIEYDTFGELKVPNDKYYGAQTVRSTMNFKIGGVTERMPTPVIKAFGILKRAAAEVNQDYG-LDPKIANAIMKAADEVAEGKLNDH--FPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKIPVHPNDHVNKSQSSNDTFPTAMHIAAAIEVHEVLLPGLQKLHDALDAKSKEFAQIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLGPK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SX99-1", "uniprot_id": "FUMH_DANRE", "id": "Q7SX99-1", "name": "Fumarate hydratase, mitochondrial", "aln": "MYRSARSLHRFSASLSDLRAAQRSIK--ARNVCPAPGLRHQTVRMASSEAFRIERDTFGELKVPSDKYYGAQTVRSTMNFRIGGVTERMPIQVIRAFGILKKAAAEVNKDYG-LDPKIADAIMKAADEVESGKLDDH--FPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGKLGSKDPVHPNDHVNKSQSSNDTFPTAMHIAAAKEVHEVLLPGLQTLHDALAAKAEQFKDIIKIGRTHTQDAVPLSLGQEFGGYVQQVKYSIARVKASLPRVYELAAGGTAVGTGLNTRIGFAEKVADKVSALTGLPFVTAANKFEALAAHDALVELSGALNTVAVSMMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMIIKNVLNSARLLGDASVSFTNNCVVGIEANTERINKLMSESLMLVTALNPHIGYDKAAKIAKTAHKDGSTLKEAALKLGFLNEQQFEEWVRPHDMLGPK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08417-1", "uniprot_id": "FUMH_YEAST", "id": "P08417-1", "name": "Fumarate hydratase, mitochondrial", "aln": "MLRFTNCSCK---------------------TFVKSSYKLNIRRMNS--SFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDH--FPLVVFQTGSGTQSNMNANEVISNRAIEILGGKIGSKQ-VHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGPK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W3X5-1", "uniprot_id": "Q9W3X5_DROME", "id": "Q9W3X5-1", "name": "fumarate hydratase", "aln": "MLKQNNGLHLARRNLWVVCSG--------LRAKDCDSGGKGGKGKENG-KFRTEKDTFGELKVPADKLYGAQTMRSKLNFPIGDIGERMPMPVIQAMGILKKACAEVNKDYG-LDGKVSDAVSCACDDVISGKLYKQGHFPLVIWQTGSGTQTNMNTNEVISNAAIKMMGGELGSKKPVHPNDHVNKSQSSNDTFPTAIHISVGMELNERLVPAVTHLRDALKSKSDEFKDIIKIGRTHLMDAVPLTLGQEFSGYTQQLTNGLERIKGCLPRVYELALGGTAVGTGLNTRKGFAEKVAKRISELTCLPFVSAPNKFEALAARDAMVEVHGVLNTIAVSLMKIANDIRLLGSGPRCGLGELMLPENEPGSSIMPGKVNPTQCESMTMLCAQVMGNQVAVTIGGSNGHFELNVFKPLVVSNVLRSIRLLADGSMTFSKNCVEGLQANKERIDKIMNESLMLVTALNPHIGYDKAALIAKTAHKNKTTLKEEALKTG-ITEEQFKEWVNPKEMLGPK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W3X6-1", "uniprot_id": "Q9W3X6_DROME", "id": "Q9W3X6-1", "name": "fumarate hydratase", "aln": "-----MVLPLLQR---STLRG--------VQQMTKPWAAIGSLRLASQ-EFRVESDTFGELKVPADKYYGAQTMRSQINFPIGGATERMPKPVVQAMGILKKAAAEVNKEFG-LDSKVSEAISKAADDVISGKLYDD-HFPLVIWQTGSGTQSNMNVNEVISNRAIELLGGKLGSKTPVHPNDHVNKSQSSNDTFPTAIHISVALELNNNLKPAIKTLHDALRAKSEEFKDIIKIGRTHTMDAVPLTLGQEFSGYAQQLAYAQERIDACLPRVYELALGGTAVGTGLNTRKGFAEKCAAKIAELTSLPFVTAPNKFEALAARDAMVEVHGVLNTIAVSLMKIANDIRFLGSGPRCGLGELSLPENEPGSSIMPGKVNPTQCESLTMLSAQVMGNQVAVTIGGSNGHFELNVFKPLIVSNVLRSIRLLSDGSRTFTANCVNGIQANRENIAKIMNESLMLVTALNPHIGYDKAAKIAKTAHKNGTTLKEEAINLGYLTEQQFNDWVRPEQMLGPK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTI5-1", "uniprot_id": "Q9VTI5_DROME", "id": "Q9VTI5-1", "name": "fumarate hydratase", "aln": "MSSTKK------------------------------------------VETRQESDTLGPMEVPMDRYYGAQTMRCLINFRIGGEEERMPRQIIQAMGILKKAAAETNQEFG-LDPKLSTAISNAADDVISGKLYDEGHFPLPIWQTGSGTQSNMNSNEVIGNRAIELLGGRIGTKDPVHPNDHVNKSQSSNDTFPSAIHIAVATALTKDLRPAVTALRDSLQAKSNEWKDIIKIGRTHTQDAVPLTLGQEFSGYAQQLTNGLQRIDAVLPRVYQLALGGTAVGTGLNTRRGFAEKCVKRIAQLSGLPFVVAPNFFEALACRDAMVEVHGALNVLAVSLMKVTNDIRFLGSGPRCGLGELFLPENEPGSSIMPGKVNPTQCEAMTMICAQVMGNHVAVSVGGANGHFELNVFKPLIASNVLRSIKLLADGCISFNCNCVKGIKPNKEKLAKIVNESLMLVTALNPHIGYDKSAQIAKAAHKNGTTLKVEALNAG-ISEKDFNEWVRPEKMLGPS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IPD2-1", "uniprot_id": "Q8IPD2_DROME", "id": "Q8IPD2-1", "name": "fumarate hydratase", "aln": "MSFDQKEIFS----------------------------LMYKLARLIVPDTRVEYDSMGAVHIPLDRMFGPQTMRSLMKFPIGGVEERMPRPLIKALGIVKKSAAETNKIHC-LEEHLCDAISKACDDVISGKLYDEEHFPLVIWQDGSGEHTNMNVNEVICNRAIEILGGQMGSKEPVDPNEHVNMAQSSHDTFSTAVRIAVAMQLQETLYPSLRTFIDLLGKKSNDWMDLIKIGRTHLMDAVPLSLGQEFSGYQQQLVNGRTRLDCAMCRLYQLPMGGTSVGTKVDTKAEYSAQCIKRIAELTFLPFVESPNFFESISACDCLVELHGELNTIAASVMKIANDIRFLGSGPRCGFGELHLPENEPGSSIMPGKVNPTQCEAMSMICAQVMGNHVAVSMGGSSGHFQLNTFMPMIASNVLRSITLLGDGMKSFCTNCLEGIEPNRSKIGSIVKESLMLVTALSPHIGYERSAAIAKAAHHNGTTLEQEAILDG-IQREDFREWVQPSKMLGPE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * *::* :.:* *: :*.** *. :* **. **** :::*:*::*::.* .*: *: ::. *: *.*:* .*** .. *** ::* *** ::*** **** * **:::**.:*:* *.**:* * :***:***.:.::*:.. : : * * : : : * *:.:: .::****** **.**:*****.** **: . *: : : *. ***:*** ::*: : : ::: : * * :.* **:::. *.:** * :*. * *::*:::*** ******.* ** ******************* *::: :..*****:.*::..*:.*:*:**.* *:: *:*.* *: *. :* :*: *::.* .: .::.:********.*:***: :: :** **:. **: *: * : ::* :** * .****.", "identical_positions": 190, "similar_positions": 153, "identity": "36.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010724-8", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62696-1", "uniprot_id": "DLG1_RAT", "id": "Q62696-1", "name": "Disks large homolog 1", "aln": "MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVISIFQSNLFQALIDIQEFYEVTLLDNP-KCVDHS--KQCEPVQPGNPWESGSLSSAAVTSESLPGGLSPPVEKYRYQDEEVL-PSERISPQVPNEVLGPELVHVSEKSLSEIENVHGFVSHSHISPIKPTEAVPP-SSPIVPVTPALPVPAESPVVLPS-TPQANPPPVLVNTDSLETPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKRRK--------------------AFRKNHEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNS----VCLEEVTHEEAVTALKNTSDFVYLKAAKPTSMYINDG-------YAPPDITNSSSQSVDNHVSPSSYLGQ--TPASP-------ARYS---------PISKAVLGDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTIVAQYRPEEYSRFEAKIHDLRETMMNSSVSSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARLKTVKFNSKTRGDKGEIPDDMGSKGLKHVTSN---------------ASDSE----SSYHEYGCSKGGQEEYVLSYEPVNQQEVNYTRPVIILGPMKDRVNDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVRAVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMENIMEMNKRLTDEQARKTFERAVRLEQEFTEHFTAIVQGDTLEDIYNQVKQIIEEQSGPYIWVPAKEKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q811D0-1", "uniprot_id": "DLG1_MOUSE", "id": "Q811D0-1", "name": "Disks large homolog 1", "aln": "MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTLLDNP-KCVDHS--KQCEPVQPVTTWEIASLPSTAVTSETLPGSLSPPVEKYRYQDEEVL-PPEHISPQVTNEVLGPELVHVSEKNLSEIENVHGFVSHSHISPIKPTEAVPP-SSPIVPVTPALPVPAESTVVLPS-APQANPPPVLVNTDSLETPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKRRKP-------------------ASEKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNS----VCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYINDG-------YAPPDITNSSSQSVDNHVSPSSCLGQ--TPTSP-------ARYS---------PISKAVLGDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSVSSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFRFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARLKTVKFNSKTRGDKGEIPDDMGSKGLKHVTSN---------------ASDSE----SSYR-------GQEEYVLSYEPVNQQEVNYTRPVIILGPMKDRVNDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVRAVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIVQGDTLEDIYNQVKQIIEEQSGPYIWVPAKEKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12959-1", "uniprot_id": "DLG1_HUMAN", "id": "Q12959-1", "name": "Disks large homolog 1", "aln": "MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTLLDNP-KCIDRS--KPSEPIQPVNTWEISSLPSSTVTSETLPSSLSPSVEKYRYQDEDTP-PQEHISPQITNEVIGPELVHVSEKNLSEIENVHGFVSHSHISPIKPTEAVLP-SPPTVPVIPVLPVPAENTVILPT-IPQANPPPVLVNTDSLETPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRLYVKRRKP-------------------VSEKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNN----VCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYMNDG-------YAPPDITNSSSQPVDNHVSPSSFLGQ--TPASP-------ARYS---------PVSKAVLGDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARLKTVKFNSKTR-DKGEIPDDMGSKGLKHVTSN---------------ASDSE----SSYR-------GQEEYVLSYEPVNQQEVNYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIVQGDTLEDIYNQVKQIIEEQSGSYIWVPAKEKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5PYH6-1", "uniprot_id": "DLG1_DANRE", "id": "Q5PYH6-1", "name": "Disks large homolog 1", "aln": "MPVRQKDAQRALQLLEEYQTKLSQTGDPHLRLSIERVINIFKSTLFQALVDIQEYYEVSLQDTEDKPIEDSSLKSRESFPPVNEWNLSVPPSTTGPTEPVPINLPQTEEKYRYQDEDTTSPPEHSSPHIPGDARPPELVQVSEKNISQIENVHGYVSHSHISPMKQADVIPPPSAPIIPVIPISPVPAETTAIIPAPASQASPAPVVVNTESLDSSPYVNGTEADYEYEEITLERGNSGLGFSIAGGTDNPHIGEDPSIFITKIIPGGAAAQDGRLRVNDCILRVNDVDVRDVTHSNAVEALKEAGCIVRLYVRRRKP-------------------LSEKIMDVKLVKGPKGLGFSIAGGVGNQHIPGDNSIYITKIIEGGAAHKDGRLQIGDKLLAVNA----VCLEEVTHEDAVAALKNTPDVVYLKVAKPTSVFMNDS-------YAPPDVTSSYSQHMENHISTQSYLSQPLTPATP-------SRYS---------PVSKGMLGDDEITREPRKIVLHRGTTGLGFNIVGGEDGEGIFISFILAGGPADLCGELRKGDRIVSVNGVDLRSATHEQAAAALKNAGQTVTIIAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRTLYVRALFDYDITKTVKFNSKSRD-------------------------------------KASLNDKRRKTLFSRKFLFSKNKDSGEQD---TSDVDQHVTSN---------------ASDSE----SSFR-------GQEDYVLSYETVTQQEVSYSRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVNSREQMEKDIQDHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQLAQLYPIAVFIKPKSVENILEMNKRLMEEQGRKTYDRAMKLEQEFLEHFTAIVQGDTLEEIYNQVKQIIEEQSGPFIWVPVKEKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P31007-2", "uniprot_id": "DLG1_DROME", "id": "P31007-2", "name": "Disks large 1 tumor suppressor protein", "aln": "MPVKKQEAHRALELLEDYHARLSEPQDRALRIAIERVIRIFKSRLFQALLDIQEFYELTLLDDS-KSIQQK---TAETLQIATKWEKD--GQAVKIADFIKSSNLNRNCAYEFNN-------DASSNQTNQSALNQNPIANNVSAQAQAEALSRTFKSELEEILNQRMRIESDTENAKEPTVEQQQKQQQAQQRSSRSPQQQNPQQQQGSKSRSGSQTVNGDDS-WLYEDIQLERGNSGLGFSIAGGTDNPHIGTDTSIYITKLISGGAAAADGRLSINDIIVSVNDVSVVDVPHASAVDALKKAGNVVKLHVKRKRGTATTPAAGSAAGDARDSAASGPKVIEIDLVKGGKGLGFSIAGGIGNQHIPGDNGIYVTKLMDGGAAQVDGRLSIGDKLIAVRTNGSEKNLENVTHELAVATLKSITDKVTLIIGKTQHLTTSASGGGGGGLSSGQQLSQSQSQLATSQSQSQVHQQQHATPMVNSQSTEPGSRYASTNVLAAVPPGTPRAVSTEDITREPRTITIQKGPQGLGFNIVGGEDGQGIYVSFILAGGPADLGSELKRGDQLLSVNNVNLTHATHEEAAQALKTSGGVVTLLAQYRPEEYNRFEARIQELKQQAALGAGGSGT-LLRTTQKRSLYVRALFDYDPNRDDGLPSRGLPFKHGDILHVTNASDDEWWQARRVLGDNEDEQIGIVPSKRRWERKMRARDRSVKFQGHAAANNNLDKQSTLDRKKKNFTFSRKFPFMKSRDEKNEDGSDQEPFMLCYTQDDANAEGASEENVLSYEAVQRLSINYTRPVIILGPLKDRINDDLISEYPDKFGSCVPHTTRPKREYEVDGRDYHFVSSREQMERDIQNHLFIEAGQYNDNLYGTSVASVREVAEKGKHCILDVSGNAIKRLQVAQLYPVAVFIKPKSVDSVMEMNRRMTEEQAKKTYERAIKMEQEFGEYFTGVVQGDTIEEIYSKVKSMIWSQSGPTIWVPSKESL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***::::::***.***:*:::**:. * ** :***** **:* *****:****:**::* * * :: . *.. . *: .:. :: : . *.::: : * : .. : : . . :: * : .. . . :: : . : : . .: .* . . .:.* . . *** :: : **:* ********************** *.**:***:*.***** **** :** *: **:..* **.*:.**:***:** :*:*:*:*:: * ::.*:** **********:*********.**:**:::****: **:*.*****:**. **:**** **::**. .* * * .*. : . . : :::.* ** .: ... * ** :**: * : :. ::******.:.:::*. ************:**::*********** .**::**:::***.*:* *:**:** ***.:* .**::********.****:*::*:: .: .**: ***:***:********** .: : *:. * : * * : ** :.. . ::.* . .**.* . : ..*: *****.* : .:.*:********:***:*******:****************:***********.******:***:* ********::****** *** *********************:*****:::******::.::***:*: :**.:**::**:::**** *:**.:*****:*:**.:**.:* .***. **** **.*", "identical_positions": 416, "similar_positions": 240, "identity": "42.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010802-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O00220-1", "uniprot_id": "TR10A_HUMAN", "id": "O00220-1", "name": "Tumor necrosis factor receptor superfamily member 10A", "aln": "MAPPPARVHLGAFLAVTPNPGSAASGTEAAAATPSKVWGSSAGRIEPRGGGRGALPTSMGQHGPSAR-ARAGRAPGPRPAREASPRLRVHKTFKFVV--VGVLLQVVPSSAATIKLH---DQSIGTQQWEHSPLGELCPPGSHRSEHPGACNRCTEGVGYTNASN-NLFACLPCTACKSDEEERSPCTTTRNTACQCKPGTFR-NDNSAEMCRKCSRGCPRGMVKVKDCTPWSDIECVHKESGNGHN-----------------------IWVILVVTLVVPLLLVAVLIVCCCIG-----------SGCGGDPKCMDRVCFWRLGLL-RGPGAEDNAHNEILSNADSLSTFVSEQQMESQEPADLTGVTVQSPGEAQCLLGPAEAEGSQRRRLLVPANGADPTETLMLFFDKFANIVPFDSWDQLMRQLDLTKNEIDVVRA-----------------GTAGPGDALYAMLMKWVNKTGRNASIHTLLDALERMEERHAREKIQDLLVDSGKFIYLEDGTGSAVSLE-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O14763-1", "uniprot_id": "TR10B_HUMAN", "id": "O14763-1", "name": "Tumor necrosis factor receptor superfamily member 10B", "aln": "--------------------------------------------MEQRG-----------QNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVV--AAVLLLVSAESALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWN-DLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFR-EEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKESGTKHSGEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKVLPYLKGICSGGGGDPERVDRSSQR--------PGAEDNVLNEIVSILQ--PTQVPEQEMEVQEPAEPTGVNMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRKLGLMDNEIKVAKA-----------------EAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIEDHLLSSGKFMYLEGNADSAMS-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O14798-1", "uniprot_id": "TR10C_HUMAN", "id": "O14798-1", "name": "Tumor necrosis factor receptor superfamily member 10C", "aln": "----------------------------------------------------------------------MARIP---------------KTLKFVVVIVAVLLPVLAYSATTARQEEVPQQTVAPQQQRHSFKGEECPAGSHRSEHTGACNPCTEGVDYTNASN-NEPSCFPCTVCKSDQKHKSSCTMTRDTVCQCKEGTFR-NENSPEMCRKCSR-CPSGEVQVSNCTSWDDIQCVE-EFGANATVETPAAEETMNTSPGTPAP---------------------------------------------AAEETMN-----------TSPGTPAPAAEETMTTSPGTPAPAAEETMTTS-----------------------------------PGTPAP-------------------------------------------------------------------------------AAEETMITSPGTPASSHYLSCTIVGIIVLIVLLIVFV---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UBN6-1", "uniprot_id": "TR10D_HUMAN", "id": "Q9UBN6-1", "name": "Tumor necrosis factor receptor superfamily member 10D", "aln": "--------------------------------------------MGLWG-----------QSVPTASSARAGRYPGARTASGTRPWLLDPKILKFVVFIVAVLLPVRVDSATIPRQDEVPQQTVAPQQQRRSLKEEECPAGSHRSEYTGACNPCTEGVDYTIASN-NLPSCLLCTVCKSGQTNKSSCTTTRDTVCQCEKGSFQ-DKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIKCKN-ESAASSTGKTPAAEETVTTILGMLASPYHYLIIIVVLVIILAVVVVGFSCRKKFIS-----YLKGICSGGGGGPERVHRVLFRRRSCPSRVPGAEDNARNETLSNRYLQPTQVSEQEIQGQELAELTGVTVELPEEPQRLLEQAEAEGCQRRRLLVPVNDAD-------------------------------------------------------------------------------SADISTLLDASATLEEGHAKETIQDQLVGSEKLFYEEDEAGSATSCL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZYZ1-1", "uniprot_id": "D3ZYZ1_RAT", "id": "D3ZYZ1-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------MLQAFLLLS-----FFVPVTAKLAQDRPADLQRLKQSP--LECPAGQYLSKEDGSCKACIDGENYTSGPN-VLPSCLSCRVCKEDKVIKSRCVKARNTECECKPGSFE-DKDSTEICQTCSN-CTDGEDEVIPCTPKANRKCVPKNTQIPQHNLG------------------------LIIGLLASVISVVLFVAVIWKT---------------KAWESVCLFMTRVYPGCEQDHE--NTVGLSLLDAQTSRKTNGSHHNTEPDR----------------------TQSSPLGRKLLVLANGNNPADALKLIFERCSTEVPFNSWDRLMRHMGLTDNQIQMVRA-----------------ETQVPCEVLYQMLLKWLYQTGLGASINHLLGALEAVGERCALEEIEDYAVKSGKFVYQNTTA------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZM4-1", "uniprot_id": "TR10B_MOUSE", "id": "Q9QZM4-1", "name": "Tumor necrosis factor receptor superfamily member 10B", "aln": "----------------------------------------------------------------MEPPGPSTPTASAAARADHYTPGLRPLPKRRLLYSFALLLAVLQAVFVPVTANPAHNRPAGLQRPEESPSRGPCLAGQYLS--EGNCKPCREGIDYTSHSNHSLDSCILCTVCKEDKVVETRCNITTNTVCRCKPGTFE-DKDSPEICQSCSN-CTDGEEELTSCTPRENRKCVSKTAWASWHKLG------------------------LWIGLLVPVV-LLIGALLVWKT---------------GAWRQWLLCIKR---GCERDPESANSVHSSLLDRQTSSTTNDSNHNTEPGK----------------------TQKT--GKKLLVPVNGNDSADDLKFIFEYCSDIVPFDSWNRLMRQLGLTDNQIQMVKA-----------------ETLVTREALYQMLLKWRHQTGRSASINHLLDALEAVEERDAMEKIEDYAVKSGRFTYQNAAAQPETGPGGSQCV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ER63-1", "uniprot_id": "TNR23_MOUSE", "id": "Q9ER63-1", "name": "Tumor necrosis factor receptor superfamily member 23", "aln": "-------------------------------------------------------------MVTF----SHVSSLSHWF--------LLLLLLNLFLPVIFAMPESYS------FNCPDGEYQSNDVCCKTCPSGTFVKAPCKIPHTQGQCEKCHPG-TFTGKDN-GLHDCELCSTCDKDQNMVADCSATSDRKCECQIGLYYYDPKFPESCRPCTK-CPQGIPVLQECNSTANTVCSSSVSNPRNWLF------------------------------------------------------------------------------------------------LLM---------------------------------------------------------------------------------------------------------------------------------------LIVFCI--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ER62-1", "uniprot_id": "TNR22_MOUSE", "id": "Q9ER62-1", "name": "Tumor necrosis factor receptor superfamily member 22", "aln": "-------------------------------------------------------------MFGFFC--SLVSSLSRWFLWRRLLLLLLLLLLNLPLQVKFAMLELHS------FKCPAGEYWSKDVCCKNCSAGTFVKAPCEIPHTQGQCEKCHPG-TFTEKDN-YLDACILCSTCDKDQEMVADCSATSDRKCQCRTGLYYYDPKFPESCRPCTK-CPQGIPVLQECNSTANTVCSSSVSNPRNRLF------------------------------------------------------------------------------------------------LLLSPLSVLIV------------------------------------------------------------------------------------------------------------------------------SVVVFRIIRR-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GM86-1", "uniprot_id": "A0A8I6GM86_RAT", "id": "A0A8I6GM86-1", "name": "", "aln": "-------------------------------------------------------------MIGFCALGFLVFSLKRSR-RSFLLLLLLLLLLNRFLQV-MAMLQSHSRQSLNSFNCALGEYRSSDLCCKLCPAGMFVQEPCTIPHTQGRCETCPPG-SFSRSAN-DLNSCIPCSTCTKEQEMVADCSATSDRVCQCQTGHYYYDPEVPEFCCPCTT-CPQGIPALQECNPTNDTVCRQSASSKTEAMIE-------------------------------------------------------------------------------------SGKKLVDHATLKMKPVTSCEF------------------------------------------------------------------------------------------------------------------------------QANLCYILSSRPAWA------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2K0D9-1", "uniprot_id": "A0A0G2K0D9_RAT", "id": "A0A0G2K0D9-1", "name": "", "aln": "-------------------------------------------------------------------------MMGKLK---------TLLLPGLLL--WVFKVSSTT-------QCESNEFKHENFCCQLCPAGTHLINPCHRNRGESECAPCQAQ-HFIDVNN-REPVCSRCSKCRDDQEEVSECSSTADRKCWCKQGTYCDSENCLEMCHDCSS-CPEGR-VIQECNATMDTVCD---SKQGLSGHS-------------------------------------------------------------------------------------PELWVILVSIAAAIATVAIAA------------------------------------------------------------------------------------------------------------------------------AGVIAFIRYSRHKKDRRALNDVNDTVSTSTML-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P83626-1", "uniprot_id": "TNR26_MOUSE", "id": "P83626-1", "name": "Tumor necrosis factor receptor superfamily member 26", "aln": "--------------------------------------------------------------------------MTRLR---------LLLLLGLLLRVAVCSVNTIT-------LCKIGEFKHENLCCLQCSAGTYLRNPCQENHNKSECAPCDSE-HFIDHKN-RESECFPCSVCRDDQEEVAKCSRTADRVCQCKQGTYCDSENCLERCHTCSS-CPDGR-VVRKCNATMDTVCDKFDSEPGQSGSQ-------------------------------------------------------------------------------------CFCFSKPLGIVVIIAAFIIII------------------------------------------------------------------------------------------------------------------------------GAVIILILKIICYCKR-----GENIQLSSTML-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1P718-1", "uniprot_id": "A0A8M1P718_DANRE", "id": "A0A8M1P718-1", "name": "", "aln": "------------------------------------------------------------------------MDKSEAMKVCMALVIFSLALVGHGAAELGVSADHQNRTARQMTCLENHEYPHNGFCCKNCEAGTYVKEKCTSGQVMGKCSPCEKG-TYAEHPT-GMEQCLQCSQCHRDQTVVAECTSTSNTKCDCKIGTFCLPDEPCEVCKKCTK-CKADEEEVSGCTPTSNTKCRRRPSHPTEGPTEKPSASNSTG------TIFVIVSILILLVICAIVGAILFLKRRQRQQSETDGNLEEVKVPIDECPRSEEEQENSRNAGLEKEEEHRPESRPLLTQETQETGSKSIPVEDEDRGLGDSLPNTTSSSQTSLSALPQIIGDSPRSSPPAQRPTDRDQTESWPREDDPPRKLLPLLGEEESLSKSFDLFDSLDVRYHNKFFRSIGVSDNSIKLAETQQPMDKVYDLLRVWMQKEGLRANINTLLQALLDLDQRYSAEHIASKAVERGYYKYE----------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * * : . * * * : : * : : * *. * : . * * * * . : *.. : * ", "identical_positions": 15, "similar_positions": 16, "identity": "2.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010803-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJA3-1", "uniprot_id": "D3ZJA3_RAT", "id": "D3ZJA3-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPPIPQSGVPLNPSSVMVQPLLDS-RVPHSRLQHPLTILPIDQMKTSHVENDYIDNPSLAPATGP---KRPRG-----GAPELAPTPARCDQ--DVTHHWISFSGRPSSVSSSSSTSSDQ-------RLLDHMAPPPVTEQASP-----------------RAVRLQPKVVHCKPLDLKGPAAPP----------------ELDKHFLLCEACGKCKCKECASPRTLPSCWVCNQECLCSAQTLVNYSTCMCLVQGIFYHCTNEDDEGS-------CADHPCSCSGSNCCARWSFMGALSLVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHTNSVICKAASGDTKASRSDKPF----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTP2-1", "uniprot_id": "SPY4_MOUSE", "id": "Q9WTP2-1", "name": "Protein sprouty homolog 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPPVPQSSVPVNPSSVMVQPLLDS-RAPHSRLQHPLTILPIDQMKTSHVENDYIDNPSLAPATGP---KRPRG-----GPPELAPTPARCDQ--DITHHWISFSGRPSSVSSSSSTSSDQ-------RLLDHMAPPPVAEQASP-----------------RAVRLQPKVVHCKPLDLKGPTAPP----------------ELDKHFLLCEACGKCKCKECASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGS-------CADHPCSCSGSNCCARWSFMGALSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHTNSVICKAASGDTKTSRSDKPF----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C004-1", "uniprot_id": "SPY4_HUMAN", "id": "Q9C004-1", "name": "Protein sprouty homolog 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPPIPQS-APLTPNSVMVQPLLDS-RMSHSRLQHPLTILPIDQVKTSHVENDYIDNPSLALTTGP---KRTRG-----GAPELAPTPARCDQ--DVTHHWISFSGRPSSVSSSSSTSSDQ-------RLLDHMAPPPVADQASP-----------------RAVRIQPKVVHCQPLDLKGPAVPP----------------ELDKHFLLCEACGKCKCKECASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGS-------CADHPCSCSRSNCCARWSFMGALSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHTNSVICKAASGDAKTSRPDKPF----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PQ80-1", "uniprot_id": "A0A8M9PQ80_DANRE", "id": "A0A8M9PQ80-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MESRVPHH-IPGVSSSIMVQPLLDS-RVPYGRLQHPLTIYPIDQMKALHLENDYIDTPAVISQQPPSHKANPRGQEVLLGAP-HHPNLSRCEVPDATTHPWISFSGRPSSISSSSSTSSDQ-------RLLDHAAPTPVVDPYTTGNS-----------HGRTLAAEQPKILSSK--NIKTLAALPE---------------EKKKHVLLCEKCGKCRCTECTLPRTLPSCWVCNQECLCSAQNLVDSVTCMCLVKGVFYHCTDEDEEGS-------CADKPCSCSHSNCCARWSFMAAVSLVLPCLVCYLPATGCAKLSQKCYDGVSRPGCRCKSTQS--CKVA--EIKACQPEKQAS---------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O44783-1", "uniprot_id": "SPY_DROME", "id": "O44783-1", "name": "Protein sprouty", "aln": "MDRRNGGDPLAPPRPPKLLPRVHRPRAPEPTLSGVDHNAGATASALASGASSAAPVAIHNNNSQQQLSISAAASNNNTISIIPASPDFDDYQIHHLTFLPQRPSSLSRNSSTASSTTATGISVSGSGSVSGSSSSFTRRRPPAPVPLNNSISNNNNNSINNNFLSHFQSAEPASNALGQPPASPVTLAQPRPESERLTNEYVDTPLQHATRSQHPAGQQDNGQTTTHHLLLLPQRNQHLHLQQHQQHLQQQQQQQQQQQQQQ--HLQHQQNQQHARLATTTQATSVGSDHTDGLLHSHLQNSTTKPPASKQPAPPRLGMGLGLGLGLGLNQPIITKQPTPATQKERMHALEELLQPGGAGGNGGPLVMAGDPSLLNPIVCPRCGRCRCEQCQSPRPLPQTWVCNKTCLCSAESVIDYASCLCCAKALFYHCARDNDLDCDDGNGTPCVDNPCSCGPYKRTQRWGWLGALSIFLPCLWFYWPMRGCMKLCEKCYGRFAGRGCRCQGIGGGGAGSGGGVGSIGSTSSMLPIVPLGVNGSGLGGGVSLSGGVTDGGLNQANGKAMDHGCSAARSILRKGDLTPEKRLLDSSPDY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. * . :.** :* * . :: ** . .* : : :*. . : . : : : * . .* :: :.::*..**: :* : : .*. . :. **. : : ::* **:*:* :* **.**. ****: *****:.::: :*:* .:.:****: ::: .. *.*:****. : **.::.*:*:.**** * * ** **.:: *. . ****: . . . . ... ", "identical_positions": 69, "similar_positions": 91, "identity": "11.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010813-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P02523-1", "uniprot_id": "CRBB1_RAT", "id": "P02523-1", "name": "Beta-crystallin B1", "aln": "MSQVAKAAA--TTAVNPGPDGKGKGTPSTGTAPAPGPTPVPASVPRPAAKVGELPPGSYRLVVFEQENFQGRRVEFSGECLNLGDRGFDRVRSLIVLSGPWVAFEQSAFRGEMFVLEKGEYPRWDTWTSSYRSDRLMSFRPIRMDSQEHKICLFEGANFKGNTMEIQEDDVPSLWVYGFCDRVGSITVSSGTWVGYQYPGYRGYQYLLEPGDFRHWNEWGAFQPQMQAVRRLRDRQWHQEGCFPVLTAEPPK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVJ5-1", "uniprot_id": "CRBB1_MOUSE", "id": "Q9WVJ5-1", "name": "Beta-crystallin B1", "aln": "MSQAAKASA--TTAVNPGPDGKGKGAPSTGPAPAPGPTPVPASVPRPAAKVGDLPPGSYRLIVFEQENFQGRRVEFSGECLNLGDRGFDRVRSLIVVSGPWVAFEQSAFRGEMFVLEKGEYPRWDTWTSSYRSDRLMSFRPIRMDSQEHKICLFEGANFKGNTMEIQEDDVPSLWVYGFCDRVGSITVSGGTWVGYQYPGYRGYQYLLEPGDFRHWNEWGAFQPQMQAVRRLRDRQWHQEGCFPVLTAEPPK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53674-1", "uniprot_id": "CRBB1_HUMAN", "id": "P53674-1", "name": "Beta-crystallin B1", "aln": "MSQAAKASASATVAVNPGPDTKGKGAPPAGTSPSPGTTLAPTTVPITSAKAAELPPGNYRLVVFELENFQGRRAEFSGECSNLADRGFDRVRSIIVSAGPWVAFEQSNFRGEMFILEKGEYPRWNTWSSSYRSDRLMSFRPIKMDAQEHKISLFEGANFKGNTIEIQGDDAPSLWVYGFSDRVGSVKVSSGTWVGYQYPGYRGYQYLLEPGDFRHWNEWGAFQPQMQSLRRLRDKQWHLEGSFPVLATEPPK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PDZ4-1", "uniprot_id": "A0A8M1PDZ4_DANRE", "id": "A0A8M1PDZ4-1", "name": "Beta-crystallin B1", "aln": "MSQTAKSAT------NQGTDAKEKGAP------------APAATSKASKTGDPGFMGNYKIFLFDQENFQGRMMEVQNECMNVCERGMDRVRSIIVECGPFVAFEQTNFRGEMFILEKGEYPRWDTWSNSYRSDCLMSLRPIRMDPMEHKICLFELSDFKGNKMEIQEDDVPTLWAHGFCDRVGSVRVPGGAWVGYQYPGYRGYQYLFECGDYRHYNEFCAFQPQIQSVRRVRDMQFHQRGCFNMTAAKQ--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.**::: * *.* * **:* .*::.. .: . *.*::.:*: ****** *...** *: :**:*****:** .**:*****: ******:*********:**:.***** ***:***:**. ****.*** ::****.:*** **.*:**.:**.*****: *..*:***************:* **:**:**: *****:*::**:** *:* .*.* : ::: ", "identical_positions": 136, "similar_positions": 66, "identity": "53.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010817-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R182-1", "uniprot_id": "ANGL3_MOUSE", "id": "Q9R182-1", "name": "Angiopoietin-related protein 3", "aln": "MHTIKLFLFVVPLVIASRVDPDLSSFDS------APSEPKSRFAMLDDVKILANGLLQLGHGLKDFVHKTKGQINDIFQKLNIFDQSFYDLSLRTNEIKEEEKELRRTTSTLQVKNEEVKNMSVELNSKLESLLEEKTALQHKVRALEEQLTNLILSPAGAQEHPEVTSLKSFVEQQDNSIRELLQSVEEQYKQLSQQHMQIKEIEKQLRKTGIQEPSENSLSSKSRAPRTTPPLQLNETENTE-QDDLPADCSAVYNRGEHTSGVYTIKPRNSQGFNVYCDTQSGSPWTLIQHRKDGSQDFNETWENYEKGFGRLDGEFWLGLEKIYAIVQQSNYILRLELQDWKDSKHYVEYSFHLGSHETNYTLHVAEIAGNIPGALPEHTDLMFST--WNHRAKGQLYCPESYSGGWWWNDICGENNLNGKYNKPRTKSRPERRRGIYWRPQSRKLYAIKSSKMMLQPTT-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FHP0-1", "uniprot_id": "F7FHP0_RAT", "id": "F7FHP0-1", "name": "Angiopoietin-related protein 3", "aln": "MHTIKLLLFVVPLVISSRVDPDLSPFDS------VPSEPKSRFAMLDDVKILANGLLQLGHGLKDFVHKTKGQINDIFQKLNIFDQCFYDLSLQTNEIKEEEKELRRTTSKLQVKNEEVKNMSLELNSKLESLLEEKMALQHRVRALEEQLTSLVQNPPGAREHPEVTSLKSFVEQQDNSIRELLQSVEEQYKQLSQQHIQIKEIENQLRKTGIQEPTENSLYSKPRAPRTTPPLHLKEAKNIE-QDDLPADCSAIYNRGEHTSGVYTIRPSSSQVFNVYCDTQSGTPRTLIQHRKDGSQNFNQTWENYEKGFGRLDGEFWLGLEKIYAIVKQSNYILRLELQDWKDSKHYAEYSFHLGNHETNYTLHVAEIAANIPEALPEHRDLMFST--WDHRAKGQLYCPESYSGGWWFSDMCGENNLNGKYNKPRAKSKPERRRGISWRPRGGKLYSIKSSKMMLQPTT-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5C1-1", "uniprot_id": "ANGL3_HUMAN", "id": "Q9Y5C1-1", "name": "Angiopoietin-related protein 3", "aln": "MFTIKLLLFIVPLVISSRIDQDNSSFDS------LSPEPKSRFAMLDDVKILANGLLQLGHGLKDFVHKTKGQINDIFQKLNIFDQSFYDLSLQTSEIKEEEKELRRTTYKLQVKNEEVKNMSLELNSKLESLLEEKILLQQKVKYLEEQLTNLIQNQPETPEHPEVTSLKTFVEKQDNSIKDLLQTVEDQYKQLNQQHSQIKEIENQLRRTSIQEPTEISLSSKPRAPRTTPFLQLNEIRNVK-HDGIPAECTTIYNRGEHTSGMYAIRPSNSQVFHVYCDVISGSPWTLIQHRIDGSQNFNETWENYKYGFGRLDGEFWLGLEKIYSIVKQSNYVLRIELEDWKDNKHYIEYSFYLGNHETNYTLHLVAITGNVPNAIPENKDLVFST--WDHKAKGHFNCPEGYSGGWWWHDECGENNLNGKYNKPRAKSKPERRRGLSWKSQNGRLYSIKSTKMLIHPTDSESFE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UZN6-1", "uniprot_id": "A0A8N7UZN6_DANRE", "id": "A0A8N7UZN6-1", "name": "Angiopoietin-related protein 3", "aln": "MLMLILLLWLSLSTTSAAPNSKKSPTEAPILITAPPTEARSRFAMLDDVRLLANGLLQLGQSLREFVHKTKSQINDIFQKLNIFDRSFYQLSVVTSEIKEEEEKLKETTIFLKANNEEIRNLSLEINSKINNILQERSQLHTKVGGLEEKLKGLSQSMMPLEQLQEITALKDVIETQERTITDLLRSVKEQHDQLNYQKIKIKSLEDKVNYDTFQDTIEKPMDLNPETPDPFRYLTTNSTNGTKDINDFPADCSEVFTRGQKTSGIYPIKPNQSEPFYVYCEITPDGAATVIQRREDGSVDFDQSWEKYEHGFGKLEKEFWLGLAKIHSIAQQGEYILHIELEDWKEEKRFIEYTFTLEGPASDYALHLAPLSGDLSDAMSNHTGMKFSTKDRDNDNHDESNCARNYTGGWWF-DACGDTNLNGRYAWMRSKARHQRRKGIYWRPSKGSSYTLKSTKITIRPSTQFQ--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : *:*:: . :: : . *. :: ..*.:*********::*********:.*::******.*************:.**:**: *.******::*:.** *:.:***::*:*:*:***::.:*:*: *: :* ***:*..* . : *:*:** .:* *:.:* :**::*::*:.**. *: :**.:*.::. :*:. * .: :..:* . * :. .. : :.:**:*: ::.**::***:*.*:* .*: * ***: .. . *:**:* *** :*:::**:*: ***:*: ****** **::*.:*.:*:*::**:***:.*:: **:* * . ::*:**:. ::.::. *:.:: .: *** :: :.. *...*:****: * **:.****:* *:*:: :**:*: *:. *::**:*: ::*: ", "identical_positions": 182, "similar_positions": 181, "identity": "38.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010822-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P13596-1", "uniprot_id": "NCAM1_RAT", "id": "P13596-1", "name": "Neural cell adhesion molecule 1", "aln": "-----------MLRTKDLIWTLFFLGTAVSLQVDIVPSQ--GEISVGESKFFLCQVAG--DAKDKDISWFSPNGEKLSP-----NQQRISVVWNDDDSSTLTIYNANIDDAGIYKCVVTAEDGTQSEATVNVKIFQKLMFKNAPTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMSWTKDGEPIENEEEDDEKHIFSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWR--TSTRNISSEEK--------ASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAP---KLQGPVAVYTWEGNQVNITCEVFAYPS-ATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDR-VEPYSSTAQVQFDEPEATGGVPILKYKAEWKSLGEEAWHSKWYDAKEANMEGIVTIMGLKPETRYAVRLAALNGKGLGEISAATEFKTQPVR----------------EPSAPKLEG--QMGEDGNSIKVNLIKQDDGGSPIRHYLVKYR-ALA-SEWKPEIRLPSGSDHVMLKS------LDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPANGSPTAGLSTGAIVGILIVIFVLLLVVMDITCYFLNKCGLLMCIAVNLCGKAGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KGPVETKSEPQESEAKPAPTEVKTVPNEATQTKENESKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13595-1", "uniprot_id": "NCAM1_MOUSE", "id": "P13595-1", "name": "Neural cell adhesion molecule 1", "aln": "-----------MLRTKDLIWTLFFLGTAVSLQVDIVPSQ--GEISVGESKFFLCQVAG--DAKDKDISWFSPNGEKLSP-----NQQRISVVWNDDDSSTLTIYNANIDDAGIYKCVVTAEDGTQSEATVNVKIFQKLMFKNAPTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMSWTKDGEPIENEEEDDEKHIFSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWR--TSTRNISSEE------------------KTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEFQYAP---KLQGPVAVYTWEGNQVNITCEVFAYPS-ATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDR-VEPYSSTAQVQFDEPEATGGVPILKYKAEWKSLGEESWHFKWYDAKEANMEGIVTIMGLKPETRYSVRLAALNGKGLGEISAATEFKTQPVR----------------EPSAPKLEG--QMGEDGNSIKVNLIKQDDGGSPIRHYLVKYR-ALA-SEWKPEIRLPSGSDHVMLKS------LDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPANGSPTAGLSTGAIVGILIVIFVLLLVVMDITCYFLNKCGLLMCIAVNLCGKAGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPELPADTTATVEDMLPSVTTVTTNSDTITETFATAQNSPTSETTTLTSSIAPPATTVPDSNSVPAGQATPSKGVTASSSSPASAPKVAPLVDLSDTPTSAPSASNLSSTVLANQGAVLSPSTPASAGETSKAPPASKASPAPTPTPAGAASPLAAVAAPATDAPQAKQEAPSTKGPDPEPTQPGTVKNPPEAATAPASPKSKAATTNPSQGEDLKMDEGNFKTPDIDLAKDVFAALGSPRPATGASGQASELAPSPADSAVPPAPAKTEKGPVETKSEPPESEAKPAPTEVKTVPNDATQTKENESKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13591-2", "uniprot_id": "NCAM1_HUMAN", "id": "P13591-2", "name": "Neural cell adhesion molecule 1", "aln": "-----------MLQTKDLIWTLFFLGTAVSLQVDIVPSQ--GEISVGESKFFLCQVAG--DAKDKDISWFSPNGEKLTP-----NQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIE-QEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWR--TSTRNISSEEK--------ASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAP---KLQGPVAVYTWEGNQVNITCEVFAYPS-ATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDQ-VEPYSSTAQVQFDEPEATGGVPILKYKAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAASEFKTQPVQG---------------EPSAPKLEG--QMGEDGNSIKVNLIKQDDGGSPIRHYLVRYR-ALS-SEWKPEIRLPSGSDHVMLKS------LDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPANGSPTSGLSTGAIVGILIVIFVLLLVVVDITCYFLNKCGLFMCIAVNLCGKAGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KGPVEAKPECQETETKPAPAEVKTVPNDATQTKENESKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B0V3-1", "uniprot_id": "A0A8M3B0V3_DANRE", "id": "A0A8M3B0V3-1", "name": "", "aln": "-----------MFPTKAIILVLLFFDNAVSLQVDITPAH--GEISVGESRFFLCEVIG--GAK--EIDWFAPAGEKIEP-----GRPDISVIRNDETSSTLTIYNAKVDNAGTYRCVASSGD-QDAEATVNLKIYQKITFTNVPSPQEFTEGDNAIIVCDVISSPPPTVLWKYKGAKIQFDKDVRFKTLSNNHLQIRGIRKTDEGVYTCEGRIKARGEVDFRSIKVVVNVLPTIRIRQAETNATADMGFSTLLACDPDGFPEPIVTWRRNNAPLE----SGNKYSFNEDGSEMTVLDVTKLDEGDYTCIAKNKAGESEQELSLKVFVQPKITYLESQTTTEMDEQVTLTCEATGDPTPTITWS--FGTRVFTEGEQEQQKRIYQASWTRPEQHKGPDGEVLVRSDARVSSLTLKYPQYTDAGQYLCTARNAIGETVQPVSLEVRYAP---KILGSVAVYTWEGNPANISCEVLAHPSDVSITWLRDGFQLPNANTSNIKIHNTPSASYLEVNPESQSDFGNYNCTTSNEIGTESREFIMIPADVPSAPSIGE-VQPYSSTAQVLFEEPESTGGVPVLKYRAEWRAVGRGKWVQRVYEVKDGLSS--VTVTGLKPETDYEVKMSAINGKGEGDSSPSMVFKTEHVRYSYTNGIFHFHTEDTGEPSPPILEG--TLQPKGNSLKVKWIKQDDGGSPITHYLVRYK-AREDSEWKPEIRLPSGSEYVMLIG------LDWDTEYDVFVVAENQQGKSKPGTLTFRTSSEPTATTDSMEDGPGLNTGVIVGILILVCVLLLLIVDATCCFLNKCGILMCI----CGKPGQSTKGKDIETGKAAFVQDVSKEPIVEVRTEEEATANHDAEGHLEPNETTPLTEPEQVTETAAAVVDLPLSVPTN---SDTITDTFDLSQSSPVSESTTLTSSITAPPSDPINPVHMTPPDSSTPKTHSRPSISSSDPANVTLLVDLAEVSPAVPSEEPVQVPSSPTSVDHPGTIISKVTENESVQGPSHAALNPISPQGDIAVPLVNHELEIDGEHPLASDTDATQDGSHAG--------------------------------------------------------------------------------GTAGSSGPSAPAQDEKILEDENAELKKVAPDAGFEPNAVTQTN-IESKA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P34082-1", "uniprot_id": "FAS2_DROME", "id": "P34082-1", "name": "Fasciclin-2", "aln": "MGELPPNSVGVFLALLLCSCSLIELTRAQSPILEIYPKQEVQRKPVGKPLILTCRPTVPEPSLVADLQWKDNRNNTILPKPNGRNQPPMYTETLPGESLALMITSLSVEMGGKYYCTASYANTEILEKGVTIKTYVAITWTNAPENQYPTLGQDYVVMCEVKADPNPTIDWLRNGDPIRTTNDK--YVVQTNGLLIRNVQESDEGIYTCRAAVIETGELLERTIRVEVFIQPEIISLPTNLEAVE--GKPFAANCTARGKPVPEISWIRDATQLN--VATADRFQVNPQTGLVTISSVSQDDYGTYTCLAKNRAGVVDQKTKLNVLVRPQIYELYNVTGAR-TKEIAITCRAKGRPAPAITFRRWGTQEEYTNGQQ------------DDDPRIILEPNFDEERGESTGTLRISNAERSDDGLYQCIARNKGADAYKTGHITVEFAPDFSHMKELPPVFSWEQRKANLSCLAMGIPN-ATIEWHWNGRKIKDLYDTNLKIVGTGPRSDLIVHPVTRQYYSGYKCIATNIHGTAEHDMQLKEARVPDFVSEAKPSQLTATTMTFDIRGPSTELGLPILAYSVQYKEALNPDWSTAYNRSWSPDSP--YIVEGLRPQTEYSFRFAARNQVGLGNWGVNQQQSTPRRSAPE-------EPKPLHNPVQHDKEEPVVVSPYSDHFELRWGVPADNGEPIDRYQIKYCPGVKISGTWTELENSCNTVEVMETTSFEMTQLVGNTYYRIELKAHNAIGYSSPASIIMKTTRGIDVIQVAER--QVFSSAAIVGIAIGGVLLLLFVVDLLCCITVHMGVMATMCR--KAKRSPSEIDDEAKLGSGQLVKEPPPSPLPLPPPVKLGGS----------PMSTPLDEKE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLRTPTGSIKQNSTIEFDGRFVHSRSGEIIGKNSAV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: *: : * * ::* * : . .**:. :: *. : ::.* .:.: * .: : . * :* * . .:: .* * *..: : * *.:* : : :.*.* * *:: :::*:* :. **: * :* : :* .:..* * **.::::*** * *.. : **: : *:* * : * : :*. * . * . * * * ::* :: :: ::. .. : . :*: .* : * . * *:*:*:** : *:*:.:*:* : . * . :::::**.*.* * *:**: . :. : : .. . ..:* :. : :* * * * * * .: :. : ..:** :: .*::** . .*::* .:. *. .:* * :* : . :*:** .* . * * * * :.. :..*:* : * * . :: : * .*. * . : ::* . : *.: *:*:* * .::: . * . : **:*:* * .:::* * * *: . .* :* * : .: :::. *.*.** :* ::* . * .*:. ...: ** * :: * : : *.* * *... : ::*: . :.:..**** * :***.::* * : : *:: : .* . . ..: : *.. : :: . .*: . : . :*** * * : . : . : :* .", "identical_positions": 163, "similar_positions": 274, "identity": "13.74%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010906-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P37136-1", "uniprot_id": "ACES_RAT", "id": "P37136-1", "name": "Acetylcholinesterase", "aln": "----MRPPWYPLHTPSLASPLLFLLLSLLGGGARAEGREDPQLLVRVRGGQLRGIRLKAPG-GPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGILDATTFQNVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTP-----------------------------YPRPTSPTP---VLIWIYGGGFYSGASSLDVYDGRFLAQVEGTVLVSMNYRVGTFGFLALP------GSREAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCPPGGAGGNDTELISCLRTRPAQDLVDHEWHVLPQESIFRFSFVPVVDGDFLSDTPDALINTGDFQDLQVLVGVVKDEGSYFLVYGVPG-FSKDNESLISRAQFLAGVRIGVPQASDLAAEAVVLHYTDWLHPEDPAHLRDAMSAVVGDHNVVCPVAQLAG------RLAAQG------------------------ARVYAYIFEHRASTLTWPLWMGVPHGYEIEFIFGLPLDPSLNYTVEERIFAQRLMQYWTNFARTGDPNDPRD---SKSPRWPPYTTAAQQYVSLNLKP--LEVRRGLRAQTCAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQERCSDL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21836-1", "uniprot_id": "ACES_MOUSE", "id": "P21836-1", "name": "Acetylcholinesterase", "aln": "----MRPPWYPLHTPSLAFPLLFLLLSLLGGGARAEGREDPQLLVRVRGGQLRGIRLKAPG-GPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGVLDATTFQNVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTP-----------------------------YPRPASPTP---VLIWIYGGGFYSGAASLDVYDGRFLAQVEGAVLVSMNYRVGTFGFLALP------GSREAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCPPGGAGGNDTELIACLRTRPAQDLVDHEWHVLPQESIFRFSFVPVVDGDFLSDTPEALINTGDFQDLQVLVGVVKDEGSYFLVYGVPG-FSKDNESLISRAQFLAGVRIGVPQASDLAAEAVVLHYTDWLHPEDPTHLRDAMSAVVGDHNVVCPVAQLAG------RLAAQG------------------------ARVYAYIFEHRASTLTWPLWMGVPHGYEIEFIFGLPLDPSLNYTTEERIFAQRLMKYWTNFARTGDPNDPRD---SKSPQWPPYTTAAQQYVSLNLKP--LEVRRGLRAQTCAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQERCSDL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22303-1", "uniprot_id": "ACES_HUMAN", "id": "P22303-1", "name": "Acetylcholinesterase", "aln": "----MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPG-GPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTP-----------------------------YPRPTSPTP---VLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALP------GSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPG-FSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAG------RLAAQG------------------------ARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRD---PKAPQWPPYTAGAQQYVSLDLRP--LEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQDRCSDL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DDE3-1", "uniprot_id": "ACES_DANRE", "id": "Q9DDE3-1", "name": "Acetylcholinesterase", "aln": "-----------MKTSDILLLPTVLLTFLFHN---CFAQAEPDLVVATRLGRVQGTRLPVPDRSHVIAFLGIPYAEPPIGKRRFKRAEPKKPWNNVFEAKEFSNACYQFVDTSYPGFPGIEMWNPNRVMSEDCLYLNVWVPP----------------------------TPRPQNLT----VMVWIYGGGFYSGSSSLDVYDGRYLAYTEKVVVVSMNYRVGAFGFLALN------GSSDAPGNVGLYDQRLALQWVQENIHFFGGNPKQVTIFGESAGAASVGMHVLSPDSRPLFTRAILQSGVPNTPWATVTFDEARRRTTKLGKLVGCTWG----NDTELIDCLRNKHPQELIDQEWQVLPWSSLFRFSFVPVVDGVFFPDTPDAMISSGNFKYTQILLGVNQDEGSYFLLYGAPG-FSKDNESLISREDFLESVKMGVPHANDIGLEAVILQYTDWMDENNGQKNRDAMDDIVGDQNVICPLQHFAKSYAQYAALHAQSSAAAPGTLGWGNSGPTGYNSGNSHGAVYLYLFDHRASNLAWPEWMGVIHGYEIEFVFGLPLEKRLNYTAEEEKLSRRIMRYWANFARTGNPNVNTDGTMDSRRRWPQFSANEQKHVGLNTEP--MKVHKGLRTQFCALWNRFLPRLLNITDNIDDVERQWKVEFHRWSSYMMHWKSQFDHYSKQERCTDL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07140-1", "uniprot_id": "ACES_DROME", "id": "P07140-1", "name": "Acetylcholinesterase", "aln": "MAISCRQSRVLPMSLPLPLTIPLPLVLVLSLHLSGVCGVIDRLVVQTSSGPVRGRSVTVQG-REVHVYTGIPYAKPPVEDLRFRKPVPAEPWHGVLDATRLSATCVQERYEYFPGFSGEEIWNPNTNVSEDCLYINVWAPAKARLRHGRGANGGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVASFQYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPVTRGLVKRGMMQSGTMNAPWSHMTSEKAVEIGKALINDCNCNASMLKTNPAHVMSCMRSVDAKTISVQQWN--SYSGILSFPSAPTIDGAFLPADPMTLMKTADLKDYDILMGNVRDEGTYFLLYDFIDYFDKDDATALPRDKYLEIMNNIFGKATQAEREAIIFQYTSWEG-NPGYQNQQQIGRAVGDHFFTCPTNEYAQ------ALAERG------------------------ASVHYYYFTHRTSTSLWGEWMGVLHGDEIEYFFGQPLNNSLQYRPVERELGKRMLSAVIEFAKTGNPAQDGE-------EWPNFSKEDPVYYIFSTDDKIEKLARGPLAARCSFWNDYLPKVRSWAGTCDGDSGSASISPR----LQLLGIAALIYICAALRTKRVF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . * :: *:* . * ::* : . . * .: ***:*:**: ** . * .** .:.:*. :. .* * :*** * *:**** :******:***.* .* . * :::******* :*:::**:*:. :. . .::.*::****:**** * : :******* ** **::*:::* ***:* :*:******::**. :::* :* *. *.::***. * **: : :* . . * . .* . * :.:: *:*. .: : ::*: . ..:: *. .*.:** *:. * :::.:.::: ::*:* :***:***:*. . *.**: : :.* .:* :. . :..: **::::**.* : : :: :. ***: . ** . * * :. . *: * * **:*. * **** ** ***:.** **: :* *. :.:*:: :**:**:* : .** :: : :. :: :* : *::** :**:: . :.. * . . . . : : : : . * . : ", "identical_positions": 175, "similar_positions": 202, "identity": "25.22%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-010919-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAW6-1", "uniprot_id": "D3ZAW6_RAT", "id": "D3ZAW6-1", "name": "", "aln": "MSHATETARDGVEASAEGPRAVFVLLEERRPADSAQLLSLNSLLPESGIVADIELENILDPDSFYELKSQPLSLRSSLPISLQATPTTPATLSASSSAGGSRTPAMSSSSS-RVLLRQQLMRAQAQEQERRERREQAAAAPFPSPAPASPAISVIGVSAGGHTLSRPPPAQVPREVLKVQTHLENPTRYHLQQARRQQVKQYLSTTLGPKLASQALTPP--PGPSSAQPLPAPETAHATGPTGSAPNSPMALLTIGSSSEKEIDDVIDEIISLESSYNDEMLSYLPGGTAGLQLPSTLPVSGNLLDVYSSQGVATPAITVSNSCPAELPNIKREIS------ETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPEMRWNKGTILKASVDYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQELELQAQIHGLPVPPNPGLLSLATSSVSDSLKP-EQLDIEEEGRPSTTTFHVSGGPTQNAPPQQPPAPPSDTLLDLHFP-SDHLGDLGDPFHLGLEDILMEEE-GMVGGLSGGALSPLRAASDPLLSSVSPAVSKSSSRRSSFSMEDES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64092-1", "uniprot_id": "TFE3_MOUSE", "id": "Q64092-1", "name": "Transcription factor E3", "aln": "MSHAAEPARDAVEASAEGPRAVFLLLEERRPAESAQLLSLNSLLPESGIVADIELENILDPDSFYELKSQPLFLRSSLPISLQATPTTPATLSASSSAGGSRTPAMSSSSS-RVLLRQQLMRAQAQEQERRERREQAAAAPFPSPAPASPAISVIGVSAGGHTLSRPPPAQVPREVLKVQTHLENPTRYHLQQARRQQVKQYLSTTLGPKLASQALTPP--PGPSSAQPLPAPETAHATGPTGSAPNSPMALLTIGSSSEKEIDDVIDEIISLESSYNDEMLSYLPGGTAGLQLPSTLPVSGNLLDVYSSQGVATPAITVSNSCPAELPNIKREIS------ETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPEMRWNKGTILKASVDYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQELELQAQIHGLPVPPNPGLLSLTTSSVSDSLKP-EQLDIEEEGRPS-TTFHVSGGPAQNAPPQQPPAPPSDALLDLHFP-SDHLGDLGDPFHLGLEDILMEEE-GMVGGLSGGALSPLRAASDPLLSSVSPAVSKASSRRSSFSMEEES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19532-1", "uniprot_id": "TFE3_HUMAN", "id": "P19532-1", "name": "Transcription factor E3", "aln": "MSHAAEPARDGVEASAEGPRAVFVLLEERRPADSAQLLSLNSLLPESGIVADIELENVLDPDSFYELKSQPLPLRSSLPISLQATPATPATLSASSSAGGSRTPAMSSSSSSRVLLRQQLMRAQAQEQERRERREQAAAAPFPSPAPASPAISVVGVSAGGHTLSRPPPAQVPREVLKVQTHLENPTRYHLQQARRQQVKQYLSTTLGPKLASQALTPP--PGPASAQPLPAPEAAHTTGPTGSAPNSPMALLTIGSSSEKEIDDVIDEIISLESSYNDEMLSYLPGGTTGLQLPSTLPVSGNLLDVYSSQGVATPAITVSNSCPAELPNIKREIS------ETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKASVDYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQELELQAQIHGLPVPPTPGLLSLATTSASDSLKP-EQLDIEEEGRPGAATFHVGGGPAQNAPHQQPPAPPSDALLDLHFP-SDHLGDLGDPFHLGLEDILMEEEEGVVGGLSGGALSPLRAASDPLLSSVSPAVSKASSRRSSFSMEEES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R1N1-1", "uniprot_id": "F1R1N1_DANRE", "id": "F1R1N1-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------MSS-RVLLRQQLMREQAQEQERREAQQQASVAQLR-PADTTPAISVSLPP----MAARPPPAQVPVEVLKVQTHLENPTKYHIQQAQRQQVKEYLSTTLGNKVATQTLGVS--PVPHSAS---APEMGPSAS---SAPNSPMAHLNLGSNKE-EMDDVIDDIISLESSFNDDILSLIDS---GLQLPNTLP--GNLLDVYNSPGMTTPTITVSNSCPADLPNIKREYTGNGIVIETEARAFMKERQKKDNHNLIERRRRFNINDRIKELGALIPKSTDPEMRWNKGTILKASVDYIRKLQKEQQRAKEIEMRQKKLEQSNQALILRIQELEIQARHHGLNATVSPGLNTEASFIQNQLLQPNASMQAGVGDGQPQSHLNMDGAMAQTSPSPFLSVPPSGSPAAVAVSGPLHL----ETFSFTELDEHASDLYPDVG-LSDILMDDVRGS-DVLFSPMSPGASKTSSQGSSVNMEDDL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38165-1", "uniprot_id": "RTG3_YEAST", "id": "P38165-1", "name": "Retrograde regulation protein 3", "aln": "-------------------------------------------------MMNNNESEAENQRLLDELMNQTKVLQETLDFSLVTP------TPHHNDDYKIHGSAYPGGETPAQQHEKLSYINTHNSNDNNNLMGSQARSNSQTPTASTIYEEAESQSSYLDDMFRTSQGGRPVTQNSISSIGQGPLRSSYSMAYDSPVDRAMNTPLQQQEGLKAELPHDFLFQHGTDDTMYNLTDDLSSSLSSSINSDMMTPNT-YSSSFSYNPQSLGPASVSSTYSPKVRSPSSSFRAGSFLSSSFR--HGSINTPRTRHTSISSNMTENIGPGSVPKILGGLT-----------SDEKLRRKREFHNAVERRRRELIKQKIKELGQLVPPSLLNYDDLGKQIKPNKGIILDRTVEYLQYLAEILEIQAR----KKKALLAKIKELEEKKSSVAALSPFTNNHHASSGQNNSENSEE-RIIDIRSVPNALMNEQNSKAELHNWEPPLYDSVGNHN--------------------HAGTMESHPHTN--IHEELKEFLSGDLIEAEDNAKLMFGDDNSNPADYLLEFGSG---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .: :.::..: . : : *: :: .. . *.. . * .:.: :.* : . * . *.. :.*.* : . :: .:. :. *: ** * . ... . : *:.*::. .: * . * *..:: . ::. : : .: ..* *..:*:* : : * *:*:: ** :***** *:::***** *:* * .* : .: *.:: * :: :* : : :::* :*:*** : . . . . : : .: : :: : . : * .. . : *. . : : * .. *:.:. ... ", "identical_positions": 53, "similar_positions": 138, "identity": "9.06%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011015-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAQ2-1", "uniprot_id": "D3ZAQ2_RAT", "id": "D3ZAQ2-1", "name": "Mothers against decapentaplegic homolog", "aln": "MFRSKRSGLVRRLWRSRVVPDREEG----------------------SGGGCGGDEDGSLGSRAEPAP-----------------------RAREGGGCGRSEVRSVAPRRLRDAVGPRGALIAGRRRRTGGPPRPVSEPGAGAGGSPLDVVEPGGPGWLPESDCETVTCCLFSERDAAGAPRDSGDPQARQSPEPEEGGGPRSREARSRLLLLEQELKTVTYSLLKRLKERSLDTLLEAVESRGGVPGGCVLVPRADLRLGG--------------QPAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGP---ESPPPPYSR----------LSPPDQHKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYD---LPQGSGFCLGQLNLE--QRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDFERSGLLQH---ADAAHGPYDPHSVRISFAKGWGPCYSRQFITSCPCWLEILLNNHR-------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35182-1", "uniprot_id": "SMAD6_MOUSE", "id": "O35182-1", "name": "SMAD family member 6", "aln": "MFRSKRSGLVRRLWRSRVVPDREEG----------------------SGGGGGVDEDGSLGSRAEPAP-----------------------RAREGGGCSRSEVRSVAPRRPRDAVGPRGAAIAGRRRRTGGLPRPVSESGAGAGGSPLDVAEPGGPGWLPESDCETVTCCLFSERDAAGAPRDSGDPQARQSPEPEEGGGPRSREARSRLLLLEQELKTVTYSLLKRLKERSLDTLLEAVESRGGVPGGCVLVPRADLRLGG--------------QPAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFTAAADGPTVCCNPYHFSRLCGP---ESPPPPYSR----------LSPPDQYKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYD---LPQGSGFCLGQLNLE--QRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDFERSGLLQH---ADAAHGPYDPHSVRISFAKGWGPCYSRQFITSCPCWLEILLNNHR-------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43541-1", "uniprot_id": "SMAD6_HUMAN", "id": "O43541-1", "name": "SMAD family member 6", "aln": "MFRSKRSGLVRRLWRSRVVPDREEGG---------------------SGGGGGGDEDGSLGSRAEPAP-----------------------RAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPESDCETVTCCLFSERDAAGAPRDASDPLAGAALEPAGGG--RSREARSRLLLLEQELKTVTYSLLKRLKERSLDTLLEAVESRGGVPGGCVLVPRADLRLGG--------------QPAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGP---ESPPPPYSR----------LSPRDEYKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYD---LPQGSGFCLGQLNLE--QRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDFERSGLQHAP-EPDAADGPYDPNSVRISFAKGWGPCYSRQFITSCPCWLEILLNNPR-------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N6X6-1", "uniprot_id": "A0A8M1N6X6_DANRE", "id": "A0A8M1N6X6-1", "name": "Mothers against decapentaplegic homolog", "aln": "MFRTRRTGLVRRLWRSRLVTAGKEG-------------------------GDGGPDDWSD-SNPEKIP-----------------------RTEYAPGNN--------------------AGSCGRRVEERG------EPGV--------LIEHDGP-LNDGSEGRTVTCCLFKD-----LPRSKNRLACRVEHRNHNNYSSLSGRERKTGAVTEQELKKCTYAFLKKLKDKSLDVLLEAVESQGGMPSGCVLVSQTEVRIGG--------------HLVSPQYLLCRLFRWPDLRLSSLLKPLCHCQSFRAE-DSQTLCCNPHHYSRLCGPVKDDTPPPPYSH----------LSPLPEHKPLNSSLPMLPYIETEATRSAGGLSQDYSDASMSPSSLAQNHWCNVAYWELRTRVGRLYPVHDASLSIFYD---LPQGTGLCLGLLPLS--PRSTSVQRTRGKIGHGILLSKEPDGVWAYNRSQHPIFVNSPTLEHHPYLSLTVRRVMPGYSIKVFDYEKSCQMQPASHPVHPEGPYDPNSVRISFAKGWGPCYSRQFITSCPCWLEILLNNHR-------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A6H2EEY2-1", "uniprot_id": "A0A6H2EEY2_DROME", "id": "A0A6H2EEY2-1", "name": "Mothers against decapentaplegic homolog", "aln": "MIFPREKKVLWRYASSNNPSNGVSAAPPAQPPRPPPPPHRPRPHQCTPSFGYSCNEEDSLAMRQTPLPPYSSIACGMDCSSSNSSSCGQSLSLSQGQGHNNNNSHPYRRLPNHMDVLPPPPSACDRCCTAPGYSCASSCDDMLIDGSDLDQDRSPDQGQVQPVDRRMISATTFTTMFRKCCGGATES-TSGSTLTIPVSTSRATAHPPQTQAQNGKRFREDFEALMKQLKRKQRNELLLAVKSRLDPPTKTQRDVVEPTTTTAPTYLQCILIPCKTQTVWEPHVTASRLFFWRELWNAKELKRLPTCP---AARDCIYMCCNPLHWFRILHQPETESPTPPYQRSKMLRLKDADFEEDSQNDAKSAALSTWSAESTSISNIYKPALYESVTTDGKDHNINSQVWCQIAYWEMAHRVGEFFHAKTNAVNIYTDGIVASEVDSMCLRDLTPAGNQIHSVVPKARHTVGLGVTLSLENGDVWIYNRGNTTIFVDSPTLSEN---LDRVCKVMPGYCLKAFETNRAELLSMRDHGHHPMGPVDYFSIKISFGKGWGRDYKRQDIMGCPCWLEVHFSHLRXQYLMLARSAGPHSASQHLVEPGMGCACDQVSSWRSRQLLQKAQKLLTRLCRQVCALTDYRPARTRWRCLAGRRSSRQLNTKQPIIWNNKGLQKKSF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .:.. :: * *. . .. * . :: * . * . * . . ..* * . . . : . ::. *. . . : . . :.:: :::*:** :. : ** **:*: . * . *: *** * :* : ** * * * * :**** *: *: ::*.***.: :. : .. . : . . .*. :. : :. . . **.:**** ***.:: . ::.*: * .: .:** * * ::* .:* *: ** * ..** ***.: .***:****. * :* ***.:*.*: ::: . ** * *::***.**** *.** * .******: :.: * ", "identical_positions": 104, "similar_positions": 122, "identity": "15.48%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011023-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P13611-1", "uniprot_id": "CSPG2_HUMAN", "id": "P13611-1", "name": "Versican core protein", "aln": "MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTS---EFLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKEATTIDLSILAETASPSLS----------------------------------------------------------------------------KEPQMVSDRTTPIIPLVDELPVIPTEFPPVG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NIVSFEQKATVQPQAITDSLATKLP--------------------------------------------------------------------------------------------------------------------------------TPTGSTKKPWDMDDYSPSASG-----------------------------------PLGKLDISEIKEEVLQSTTG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VSHYATDSWDGVVEDKQTQESVTQIEQIEVG-------------------------------------------------------------------------------------------------------------------------------------------------------------PLVTSMEILKHIPSKEFP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VTETPLVTARMILES---------------------------------------------------------------------------------------------------KTEKKMVSTVSELVT--------TGHYGFTLGEEDDEDRTLTVGSD--------------------------------ESTLIFDQIPEVITVSKTSEDTIHTHLED-------------------------------------------LESVSASTTVSPLIMPDNNG----------SSMDDWEERQTSGRITEEFLGKYLSTTPFPSQHRTEIELFPYSGDK-------------------------------------------------------------------ILVEGISTVIYPSLQTEMTHRRERTETLIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------EMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMTKSFD----------------------------------FPTLITKLSAEPTEVRDMEEDFTATP----GTTKYDENITT-------------------------------------------------------------------------------VLLAHGTLSVEAATVSKWSWDEDNTT-------------------------------------------------------------------------------------------------------SKPLESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDG----------------ADEFTLIPDSTQKQLEEVTDEDIAAHG-------------------KFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPIT--------------------------------STEGQVYATMEGSALGEVEDVDLSKPVSTVPQFAHTS----------------EVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVP-----------------------SEDEVLGEPSQDILVIDQTRLEATISPETMRTTKITEG------------TTQEEFPWKEQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDE----LLTGSERVPVLETTPVGKIDHS------------------------------------VSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKTSLEDIDLG---------------------------------------------SGLFEKPKATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSS---------------------------------------------------AITKKPPLIDREPGE-----------------------------------------------------------------------------------ETTSDMVIIGESTSHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPTRPPTVEDK----------EAFGPQALSTPQPP---ASTKFHPDINVYIIEVRENK---------------------------------------------------------------TGRMSDLSVIGHPIDS------------------------------------------------------------------------------------------------------------------ESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAP---------SQNFSDSSESDTHPFVIAKTELSTAVQPNE---------------------------------------------------------------------------STETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVG---HQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVTFG-------------------------------------------------------------------------------------------------------------------EEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGN------PWPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEVP---------------ATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTG----------------------------------TASTFEVYSSTQRSDQLILPFELESPNVATSSDSGTRKSFMSLTT----------------------------------------------------------------------------------------------------------------------------------------PTQSEREMTDSTPVFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLP-----RSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEVAG-----TLSPHVETTFSTEPTG---------------------------LVLSTVMDRVVAENITQTSREIVISERLGEPN-------------------------------------------YGAEIRGFSTGFPLEEDFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPSTVPTSVHISHISD------SEGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQK---------------------------------------------------------------------------FSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSG-----TVSTNFPQTIEPAKLWSRQEVNPVRQEIESETTSE------------------------------------------------------------------------------------------------EQIQEEKSFESPQNSPATEQTIFDS------------------------------------------------------------------------------------------------------------------------------------------QTFTETELKTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTP----DPDANGLESYTTLPEATEKSHFFLATALVTESIPAEHVVTDSPIKKEE----------------------------------------------STKHFPKGMRPTIQESDTELLFSGLGSGE--------------EVLPTLPTES-------VNFTEVEQINNTLYP--------------HTSQVESTSSDKIEDFNRMENVAKEVGPLVS-------------------------------QTDIFEGSGSVTSTTLIEILSDTGAEG-PTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNKNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAP-----------------------------------------------------------------------------------KPSDLYYEPSGEGSGEVDIVDSFHTSATTQATRQESS------------------------------------------------------------------------------------------------------------TTFVSDGSLEKHPEVPSAKAVTADG-------------FPTVSVMLPLHSEQNKSS------------------------------------PDPTSTLSNTVSYERSTDGSFQDRFREFEDSTLKPNRKKPTENIIIDLD-----------------------------------KEDKDLILTITESTILEILPELTSDKNT------------------------------------------------------------------------IIDIDHTKPVYEDILGMQTDIDTEVPSEPHDSNDESNDDSTQVQEIYEAAVNLSLTEETFEG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SADVLASYTQATHDESMTYEDRSQLDHMGFHFTTGIPAPSTETELDVLLPTATSLPIPRKSATVIPEIEGIKAEAKALDDMFESSTLSDGQAIADQSEIIPTLG--------------QFERTQEEYEDKKHAGPSFQPEFSSGAEEALVDHTPYLSIATTHLMDQSVTEVPDVMEGS--------------------------NPPYYTDTTLAVSTFAKLSSQTPSSPLTIYSGSEASGHTEIP--------------------------------------------------------------------------------------------------------------------------------------------QPSALPGIDVGSSVMSPQDSFKEIHVNIEATFKPSSEEYLHITEPPSLSPDTKLEPSEDDGKPE--LLEEMEASPTELIAVEG--------------------TEILQDFQNKTDGQVSGEAIKMFPTIKTPEAGTVITTADEIELEGATQWPHSTSAS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATYGVEAGVVPWLSP----------------------QTSERPTLSSSPE-----------------------------------------------------------------------------------------------------------------------------------INPETQAALIRGQ----------------------DSTIAASEQQVAARILDSNDQATVNPVEFNTEVATPPFS----------------------------------------------------------------------------------------------------LLETSN--------ETDFLIGINEESVEG-----------------------------------------------------------------------------TAIYLPGPDRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLPSYVGALCEQDTETCDYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDYQWIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNYHLTYTCKKGTVACGQPPVVENAKTFGKMKPRYEINSLIRYHCKDGFIQRHLPTIRCLGNGRWAIPKITCMNPSAYQRTYS------MKYFKNSSSAKDNSINTSKHDHRWSRRWQESRR-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PX21-1", "uniprot_id": "A0A8M9PX21_DANRE", "id": "A0A8M9PX21-1", "name": "Versican core protein", "aln": "MLLNIKHILWLFCIYHSTTGPVSSTLLEMRPVSGLLSGKVTLPCYFSIMPTIGPRNKDASGYDYLRIKWTRIDGG------VESTVLVTQNGVIKIGSGYRSRVSVQSHPEDIGDASLTMVKLRASDAGTYRCEVMFGIEDTQDTVNLNVDGVVFHYRSKVSRYILNYAQAVQACSDVGATIATSEQLRAAYEDGFDQCDAGWIADQTVRYPITRPRPGCFGNLPGKPGVRSYGKRKPTETYDVFCYVDKLEGNVFFAPTLQKMTFDEAKAVCESNNAELASPGQLHAAWRQGLDRCDYGWLSDGSARHPVSVPRSQCGGGLLGVRTMYRYRNQTGFPDPSMRLGAYCFQGTKIIFNQSSWIDVTIKSSTTIKPTTPFFSTKTTTGQTLIPDASSSNAITENNLSPTDAPSMFSTSMAPPKTSRVPDRLESVYTSYSAAVSVKSEESFSTTKLSDFDIEDFGAEKADDDAKVRGDVVRGELTTVAPKVTEEPMEEPEDKIIIKVKTVLPDVLLSAPPSTKPMFAIGRTEESIVVGVTTDRDLGTDATVLNTEESEHKTESSSQTASESSSGKDEDVSRASTRSTEATFLESANTVIPEYEDETADGVVMAGPPPLSTQSSTSPHPESSENSSGLNITDSAVTPTVFMQSTTQRPTIESSVTSQKGSQTFSSFSEKESTELTDHVTRSAVLITLSSGTVAAGAVITTPSVADHETTQEETASGPSDAPKETLTEATHTTAASDHASVNERLMPFEEPHSHIAQMVVIPELPDDVLTSDGVTVMESVDFLSSATVTPTDSYINGNLEVTLQPKVVTKEPRGDTFGSDSLGVTDKIETFELDSSLVEPGRTAHESLVSGSTIVSPLFSTTLDPNIEFGQINLVVESTLPSASIEITKEEMLISEGTNIPTSANEKQSSAKPVHAATPLDHDDTTESHISPQVHSVSSITGDKAKDTAATTKVIAKTAQKDEFTTTSPPTEITSASLDHLDTDKVSLGVHTPEVFTLIPPIQVHTTSELDTTNTQRESLIETAEMHTEKPSESIMDSTKKADMTTAKVELSTLHFSSVAPHSMAEASGVETSDMLRSTTLSNALYTTTKSDHKSMETTEKIPLSSSTKDELSNVETTEGHITESVSSLDFTEIFISSTVKPTEQTIIGQVSTSQSATISATVIEDDLSSKPPESTITDVLETLSNEALSKISLTNTMTSEKTTAKDVPSPSSLFSRLPSTESESSESGFPSKQFTSTGFSLISTTHSDQVFIKTSSEREKSTPVSGSTHAKATSDQTSEAHSREPVSLYGTVHTFASSTWGSTGQTVKSQDITSYAATSPVTVTEDRFLSAKPSESTKTDLPESLFSTPWTDNLDKTLSKITVTMTSENIVGQDTVSASFSSSFPSTESASSKHGTSDMYSKEFKTTSSSLFSTIKSDKEPIKTTSEREETDQTHAEATRGQTSEPQSREPVSTLDSTLSNTVHTFTFSTESSTGQSVPSQYMTSNTPTTTMTVMDRYLSTKPSESTVTYVSETLSSSAQTRYLDKPLSESTDTETSEKTTSTDVLSPSSLPSTGSEALSISSSTETKRDQRTETYSTEPISSVDLTESNTGYALTSLKTGDSTGQTVTSEDITSHTATPTATVMEDKELSAHTSHSAIIDDSGTWFSSTKAGDLDETTHGSTLTLKPTARDILTQSSFPSTVSKVSGDETSEIFSKDYTSYTLQTATILDQERSKPQSNTTETTELSSLTHAEDDQATETQSKDTAYTLDSATSTVHTFRSSGTEYSTGQAVTRQSITSHAATTTETVIEDKELSVKPSETTVVDVSGTLFSSQTDHLDKTSESPVTIQLESTTAKDILSPSSFLSSLPSTQTEHSVDETSDVFMTTTISMSSSSDITKDQTTYSTEPAFSLLNLSTEFSEVYTLTPLNTGYSTDKSEDVTSHIASNTATVMEDKHLSAISSEPTVFDETFLSSAQTGHIDNKSDAVSSTSLSSILPSKEIETSGDLTSEMFSKVFTTSSSLHTTAASVMDDQTTEIHSREPAFTPDSTSFSTMLIFTPSNTEYSTGRTVTSQYITSLTETAIKDTSLSSKPSDSQGLHTLSPLGTSEFTGSIVTLEDNTSDTEKGTNVIEQRGTFGMPTVSTIIDMSESLSSSANTEYLFEKSSEGTISSHDTTSKDIGLLSRLPSIDSEGSGEQISETPTTTGSLLQEKGLSTKSSESTVTDFSEKIFSSAQTGHLDKILSESTVTTTMTLKKTTAQNEPSPSSFFSTIRVDQEHTKTSSDMGETQDKTTRYQTTWTHGREPVSTAETSTEHAITASITEYTTGHTVPKQGITSYTATTAATGIEDKELSAHSSKSTISEASETFFSSAQTDHLEQTSKSTVTIASENTTAKDVISLILSQTVKSQDTASTVIIQGSTPFTATTAATVMKYEEVSTKPSESTIIDVSETQFSSAQTGHLDEISSESTVTSKMTSDKTTPKDVLSSSLSSSFPSTESKASGDGTSEMFIKQFTTSSPLHTTTISDRELTKTPTDREETISVSISTHAETVRDQTIVAQSRQPDPMLDSTETSTLHTFTLSTTENSTEHSTTSQDIPSAKPSVLTSTDVSETSFSSFQTDHLDKTSEINVTVTSDKTIAKDFVSPTSLLHTASRSDEDHTKPTETITVSSSTDAAVTSTKSSEKTTARDLFSTSRLALILSSSESESSGDGTVDVTSSEFTTSRSSLYTTPKPYTDLRKTTFHTTEAVSVSSSTHVEDQKTETDSTGPALSFMSTASITKHSFTSLSTGESTGQTITSQDTALTERTVTNQSSTPFTGTTAATVMKDEEVSTKPSESTIIDDLETQFSSTQTGDLDNISSESTVTSKMTPDKTTPKDGLSCSLSSSFPSTVSEDSVDETSEKTIAKDLLSPISLLHTTSRSDKDLTTPTETISVSSSTDAAVTSTKSSEKTTARDFFATSTIASILSSSESESSGDGTVDVTSSEFTTSRSSLYTTPKPDKDLSKTTFLTTEAVSVSSSTHVKDQKTETESTGPASSLLSTASMTKHTFTSLSTGESTGQTVASQDTASTVRTVTIQSNTPVTATSVMQDTKVKTKPSESTIIDVSEMEFSTAQTKNLDEISSDITVTSTMTSDKTTPKDVLTSSLSSSFLSTKSEASGDDTTEKFIKEFTTSSPHFTTTLSDQELTRTPSDTETTILVSSSAHTETVSNQTIEAQSREPVSMLDSTETRTMHTFTSLNIEYSTAQTVASQDTASMVRTVTNQGSTPFTTITAANVIKDEEVSTKPSKFTITDVSETQFPSTQTGHLYEKISESTFTSAMTSDKTTPKDVLSSLSLSSSFPSTESKASVDETLEKTTAKDLLSPTSLLHTTSRSDKDFTKPTETISVSSSTDAAVTSTQSSEKTTARDFFSTSTIASILSFSESESSGDGTVDVTVSEFTTSRPSLYTTPKPDKDLTKTTFHTTEAVSVSSSTHVEDQKTETDSTGPASSFMSTAYITKHSFTSLSTGESTGQTVTSQDTASTVRTVTNQGSTPFTATTAATVIRDEEVSTKPSESTIIDDSETQFSTQTGHLDEISSESTVTSTMPSDKTTPKNVLSSSLSSSFSSTESEASVDETSEKTTAKDLVSPISLLHTTSRSDKDLTKLTETITVSSSTDAAVTSTKSSEKTTARDFFATSRIASILSSSESESSGDGTGNVTSSEFPTSWPSLYTTQKPDKDLSKTTFHTTETVSVTSSTHVEDEKTETDSIKPASSLMSTASITKVTFTSLSTGESTGQTVTSKDTASTIRTFTNQGSTPFTATTAATVMKDEEVSTKPSESTIIDDLETQFSTTQTGDLDNISSESTITSTMTSDKTTPKDVLTLSFSSSFPSTESETSGDETSEKTTAKDLVSPISLLYTTSRSDKDLTKLTETISVSSSTDAAVTSTKSSEKTTARDFFATSTIASILSSSESEISGDGTEDVTSSEFTTSRPSLYSTPKPDKDLSKTTFHTTEAVSVSSSTHVEDQKTETDSIKPALSFMSTASITKHTFTLSTGESTGQTVTSQDTASTVETVTIQSSTPFTATTATSVMQDTKVTTKPFESTIIDVSEMQFSTAQTKRLDEISSEITITSKMTSDKTTPKDVLSSSSLSSRFLYTESEASGNESSEMFIKEFTTSFPLHTITISDQELTRTPSDTETMIPVSRSAHTETVSNQTIEAQSREPVSMLDSIETRTMHTFTSSNTEYSTAQTLASQDTASTVEKVTNQGSTTFTTTTANVMKDKEVSTKPSEFTIIDVSETQFLSAQTGHLDEISSESTVTSKMTPDKTTPKDVLSSSLSSSFPSTESKASGDGTSEMFIKQFTTSSPLHTTTISDRELTKTPTDREETISVSISTHAETVRDQTIVAQSRQPDPMLDSTETSTLHTFTLSTTENSTEHSTTSQDIPSAKPSVLTSTDVSETSFSSFQTDHLDKTSEITVTVTSDKTIAKDFVSPTSLLHTASRSDEDLTKPTETITVSSSTDAAVTSTKSSEKTTARDLFSTSRLALILSSSESESSGDGTVDVTSSEFTTSRSSLYTTPKPYTDLRKTTFHTTEAVSVSSSTHVEDQKTETDSTGPALSFMSTASITKHSFTSLSTGESTGQTVTSQDTPLTERTVTNQNSTPFTETTAATVMKDEEVSTKPSESTIIDDLETQFSSTQTGDLDNISSKSTVTSKMTSDKTTPKDVLSWSLSSIFSSTVSEDSVDETSKKTIAKDLVSPISLLYTTSRSDKDLTTPTETISVSSSTDAAVTSTKSSEKTTARDFFSTSTIASILSSSESESSGDGTVDVTSSEFTTSRSSLYSTPKPDKDLSKTTFHTTEAVSVSSSTHVEDQKTETDSTGPASSLLSTASMTKHTFTSLSTGESTGQTVASQDTASTVRTVTIQSSTPFTATNVMQDTKVTTKPSESTIIDVSEMQFSTAQTKRLDEISSEITITSKMTLDKTTPKDVLSSSSLSSSFLSTESEASGDETSEMFIKEFTTSFPLYTTTISDQELTRTPSDTETTIPVSRSAHTETVSNQTVEAQSREPVSKLDLTKTRTMHTFTSLNTEYSTAQTVASQDTASTVRKVNNQGSTPFTTITAANVIKDEEVSTKPSESTIIDVSETQFSSTQTGDLDTILSESTVTSKMTSDKTTPKDFPSLSLSSSFPSTVSEDSVDKTSEKTIAKDLVSPVSLLHTTSRSDKDLNTPTDTTSVSSSTDAAVTSTKSSMKTTARDFFATSRIASILLSSESESSGDGTVDVTIPEFTTSRLSLYTTPKPDKDLSKTTFHTTEAVSVSSSTHVEDEKTETDSIKPASSLMSTASITKPTFTSLSTGESTGQTVTSQATASTVRTVTNQSSTPFTATTAATVMQYEEVSTKPSESTVIDDLERQFSTTQTGHLDEISSESTVTTTMTSDKTTTKNVLSSSLSSSFPSTESEALGDETSEKTTVKDLLSPTSLMHTTSRSDKELTKPTETISVSSSTDAAVTSTKSSEKTTARDFFSTSTIASILSSSESESTGDGTVDVTSSEFTTSRPSLYSTQKPDKDLSKTTFNTTQAVSVTSSTHVEDQKTETDSIKPALSFMSTASITKHTFTLSTGESTGQTVSSQDTASTVETVTIQSSTPFTSTTATSGMQDTKVTTKPSESTITYVSGMQFSTAQTKHLDEISSEITITSTMTSDKTTPKDVLSSSSLSSSFPSSESEASGDYTSEMFIKGFTTSSPLFTTTISDQELTRTPSDTDTTIPVSSSAHTETVSNQTIEAQSREPVSILDSTVTRTMHTFTSSNTEYSTAQTVASQDTASTVRKVTNQGSTPFTTTAANLMQNEEVSTKPSESTINNVSEMQFSTAQTGHLSEISSESTVISTMTSDKTTPKDVLSLSLSSSFSSTESEASVDETSEKTIAKDLVSPTSLLHTTSISDKDFTTPKETTSMSSSTDVAVTSIKPSEKTTGRDIFSTSRIASILPSLESESSGDGTVDVTISEFTTSRSSLYTTPKPDKDLSKTTLHTTEAVSVTSSTHVEDEKTETDSIEPASSLMSTAYVTKHTFTSLSTGESTGQTVASQDTASTVRTATNRGSTPFTGTTSPTVMQDEKMSTKPSESTIPYVSEMQFPSAQTGHLNEISSESTVTSTVPSDKTAPKDVLSPSSLYSSFPSTESEASGDNTSEIFIKEFTTSSPLYTATISDQELTRTPSDKEERISFSSSTHGETETEQTIEAQSREPVSMLDFTETSTVHTFTSSNTEYLTEYTMSSQDIKSHTTTTTAILLKDKELSANPSVLISTDVSETMSSSTDPDVTSTTSPEKTTVRDFSSTSRIAFMILSSSESKSSGDETVDVTSSEFKTTSLKPPHPSSHTTSKPEQDLSKATFTTTEAVSVTISTHAKNQSTETESIKAASSIVSTAFSTLNTFTSLTAGESTEQTVSSQDNKSAAQTGSIQDSTPFTATTPAIAMLNEEVSTKTSEFTVIDVSETLFSSAQTRNLDEISSKSTVTSKMTSEKMTSNILSSSSFSSSFPPTKTEVSEDDTSDIFSKELITSSYFQTTYQPDQELTKTSSDGEETISVSSSAHADTTRDQKINAHSREPVSVLDSFESSTVHTFTSSSTEYSTEHAVTSQGITSNVATIIATVVEDKELTAKTSESSFIDVSDTFLSSTQINHLDNTTQTENSGILTSEKTTTKDAGSPISLLLTTSRSDKELTKPTEIISVSSSTDAAGTKSSEKTTARYFFSTSTLASILSSSESEISGDGPVDVTSSELTTSRSSLYTTPKPEQALSKATFQTPEPISVTSSTHAEEQRTDNSGDSTSENISHHSTKAHSSEPVSTLGSTVTSTVHTFTSLITGESTAQTVTSQDITSDTATTTATVMQDKELSVKPSESTINYKSETVFTSDQTNDKTSQSTVTMISEKTTLSSSYFSSRLPSTESDFSGDYSSEMLSKEFTTSPLPYTTTKSGLEFSKTPNTILVSSDEDRITPTAKSHDQYNVDTDETEVQESDHTLEPVRPDSLSTTELFSGKVQKVITESSIEQGSGELSESSGEISSSAVESIPPQVTPSEVKTTAVGSKSIADSREQSSDNITTTIYVRTTVNGYAELSSVTFEEVESSDHQTTEMFTTAPLELLTTSLPGSAIATHTASVPSRPYHTITDAQSARHTTESMISHAAVKTSKPSHITSSTVQTTPASLSHSQPLIDNTSYKVTSATARTRPITLSSSENHSKHTTLSSVDAEGDAGNEEKSGMSTPMGVSAAAIRTQTRTVHITSTEPDSRITITQSSNTITSVLSDSEGSGVVEDDRETAQLDGSGEEESVSTTAELYDNYTVATDEAEISDNVYTSKPVSIESFSHSVSSTTESTLLSSTVQTVISATEVTAESELEDDSSGSEFSPEALETVPGDMSSIGKTQGTEDALLDKVVSSTSETLSVSGTQNSTLQTRTINTDLSSQTKEDGKELTLPDDSTGYVFRTPTTKSYDDLTVRTDEAEVDETEKTSFSSAASVIGSTDVVHQSTSSPSPSVLISTQPAVTFTISNLEDDSGDDSTETDGAEDGSGDDTTYVTSSPLLSSSEMTEASISITPVSSVSSGEDITATVVLHSTITPEMQTVSSSTDAESYSLFSETEQEPTGGSVLDSTATSFTVLVTSSDMATSHIASPSAVTSQASVSTPTSSVSLKDTVDQVTSTSSVLIFTEEEEDEDKLFLTATASMRHTLNPEVTTKDDMIIDVDTMSVLEQSSPFALTIVTEEAAGVTPVVITAHPSNLMTEEPVGSGMDSTELPEFYAKSETIADESIHRHQQATSTPDILQSSPTYVDREPQATQTEQSENTNNDLPEQYSHIFTEPTLTMGTLTNNSASSASTESYIKTSTLSSQSVLIIQAGSSQASITKSETMSSTAVEGQTTPLPLHRMTSEAEASSQLTNQYEPTQTTTSILSVNTEEILEMTSANDIEQSTPSSDMVSQESESTNADVSSDISEKTTSALSTDDDSGDQIIDSFTELPELTESFLTDESVTFSMETDIEIHFATTLSPQANTVTDGELHQEALSEMTVTHKDNTEFRTDEDQPLSLTTMPTPLTSESNFNTTINIVTLVGSLSSTSIPGQSKKTGTTLPSEELTDDSIDYDTKTEPYNVESIPDFYSSENVTNTNDATQTGNEKSFTTSQPDIETGFDTTSQYEIETGFDTTLQPNVATGFETSSHSDTDNTFEDISESTADPDIEASPKPSENSASTDGNKVNQTDFESAAPFDVSSEAVTSFNDITQPDSVRIFTMSKPEIETGFEATSQPDIGTSFETSSYSYTQTTFDVISESTAGPEIEGSSKPSEDSASTDGDQVNQTAALLGVSSEHVTSTSDITQPENMGSITRSQPDIGTDFETTTQSDIESTFENISESTAHPEVGMSSEPDEDNGTSIDGNTENDASVTSPPFSRTSGLGRSTSGEVTNTSSEKHTTSTTPSEVTDEPNSAAINEEKYQEEGGREDTTLAEQTDIRFRSTAQPQFDNSFTSSIVKSSSEEGSIINSSSGEVQAVILSTTTGSPLLLTPENDVKIVSKETSSEKQEAAGQIEEAVTLKTEIPIQEMDLMTSSVPTTQSETATTLASPEDVLEAALVESSPTSAQNETTTRGAKDVAYPMIAQTVEIPGVHSCSDAVCLNGGTCIKTGGAQICICQPGYSGEQCEIDIDECHTNPCRNGGTCIDGLNSFTCLCLPSYAGALCEQDTETCSYGWHKFQGHCYKYFPHRRNWDTAERECRLQGAHLASVLSHDEQQYINRLGHDYQWIGLNDKMFENDFRWTDGRVVQYENWRPNQPDSFFSSGEDCVVMIWHEDGQWNDVPCNYHLTFTCKKGTVSCSQPPIVHNARTFGQPRPRYEINSLIRYQCMDGFIQRHVPTIRCRGDGLWDSPRISCMSPSNYQRSYTRRLQRYSVYRNNRKRSAEHSVDVHRRRHHHHHHHHGGKHIRTKQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::*** ***: . * . . .: : ** * *****:***:** ***: * : : ::*****::*: . *:****:*** ****..*:.**** :*** :******:*** ***** ***:**:*********.*.*********: .*** **: * :** ****.***.*** *******:******:********* ** **:*: **.***:** *.* *****:****:*:*:**. .. .*:**:** **.::*.**: *:*:****:*:*:********.*.****:*.*:***********:**:.****** *. *:.****: ..: .**: *: ::..* ::* :* * :.. . *. : :* :* :. . . . ** .*.**:.. .* *.*::* * .**.* *. *: .*:.::. .*.*: :: .*::: . * :: :*: : : *:***: . . :: ::*. *:* .: . :****: ::*** .*. :: *. .**: :.::::* .* * * . . **: *:. *. *.* * *. ::: : .*:** * : : *:.:*:.:**:. : .*:. **: . *.: :.. :* *: :: :::*: : :: ** . *: : .:* . :.*:**: .: .. :. :. : : *:. : :.:** *.* *:.. ::**. **. : : ..:::.: **: ::: *.: *. : : :*: :. *:: *:::** .:*: ::**.::* * . * ::* :.* : .* **.: .: : * : .:* * .** .. :* * * *:. : * *::: * *:. .:.*.:..: :.. :.::: :.*:: .*:* : *::* .:. *:: .. * :.* ..:..:: :* :. . ::* :* ..*: *...* * ..*. :. . : . **.* *: : *: * : * ..:: . . ..:*: :*: * .* : *..:: ***: .*.:.*.*. *. *.: * .: :*.. .*. **.. * .. : *.. .* ::* :..: : . .:.*:. .*:. .: *. .: : * ...:*:* * *...:: : ..*: . *. : :. :*::.* . .:*:: *. *.::**:* * . * :. :*.* .: .*:. : *: * ..* :*.:*. *::*:**: .: .: . :... : *. ***:* :.*.**. * : . . : *. *.* .* :*::* *::. ** * . * : .. .: : *::. . *: :* ..* *.:. : .: *:* *.: :. . ** *. . * *. : ..* * : .:.**::. ..* ** * :*..* :. :. **:.:...:*.*:.:. . * *. .. :..:* . * *::...*.**: * .: : : ::.*:.: :*:.:. :. .* ... * *... *: .:* *.*:: : * . ::. *: ..:* :: .*.* :: :.: :*.: ::.: . ..:: : :.: *::.:.. .* .**....* *..** .:* : :::*::*: . ..*. ::* *:.:..* ***: .** . . ... *: * *:::* **:* *:::* :. * ...*** : :.: **: * * : . : *:. *.*... .*.:..:. . :. :.*: . : ::**: *: ** **: ** * **: : .*:*: .:.: * .*:: * .* : * * * :. *.: *** *:.. :.. :: . * : .* .: . : :*:.* * *:*:::**:::. *** : *.. ...*.:....: :..:: *..* *. :.: .* **::: :::: *:. ...: . .* :.**. ..**: .:. . .::* . : .: .. ***:*.: **....* *. :.. ::* . : :***.:: : : ..::::.* * :::.::.:: .. ::. : :.. * :*: :.:* .. *. ::* . . *:: . .* * *.*.. ..* .*.*:: .:.: ..* .:**:* :** *.::*. ..:**. *. *. *** ::** : : : ...*:* :* .** ..*.** ::.* . *: :.:*: ::: .*. ** : * . * : . .* *.::..:* . : .** * * : .: * :* *:: . :*.: :.*.:*. :.: .* *:.:* : . : * ** ** .* * .*: *..: * . *.* :: * *.:.: * *:* *. *.* : *: **.* :. .::.. : *.: .:*...: : :**:* :. :**** : :..:* * *: .*. :. :.* * .*...: : . ** .. *::.. *: :**.::* : *.* . . :: .*::: .. .: :.*.:.: :.* :: ** :: : *..:* : :::: :*: ::* * ...*.. . : : . * :: * :. ..: : .* .** : : * :* ** : . *:* *..* .*. . . :::* : : *.* :.* .: : *.. *:.* * *.:: *.* .*.. ::. : * * : .*:* ** *:*: .* : * .....* : . :* : ** * * * .: .::.:.*.: : : . :*. : :.* : :*: .*.: :**.:* : * :*:*. . *.* ::: * :.:**: :**. .:: *.* ..: * .* :::. :.*. : . .* ::.*::**** :*.*:. *.*. * :* * * :: :** . *. ******* * : :* * *****:***:*:****:******.**:**:*:* *******.***********.********:*****.***.**:************:*:***:** ::**:***************:******* .:***************:******:****:*************:*******:*.***:*.**:***: :***********:* *******:***** *:* * *:*:**.** ***:*: * :* . : ::*::. :: *: :: : .:: ", "identical_positions": 1012, "similar_positions": 1340, "identity": "11.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011101-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACZ1-1", "uniprot_id": "D4ACZ1_RAT", "id": "D4ACZ1-1", "name": "", "aln": "------MIAAQAKLVYQLNKYYTERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMIADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQ---SSAESDAWVLQFGEAENRLLMGGCRNKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDEACLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALESAAKQTWRLAREILTNPKSLDKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BPP1-1", "uniprot_id": "MB212_MOUSE", "id": "Q8BPP1-1", "name": "Protein mab-21-like 2", "aln": "------MIAAQAKLVYQLNKYYTERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMIADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQ---SSAESDAWVLQFGEAENRLLMGGCRNKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDEACLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALESAAKQTWRLAREILTNPKSLDKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y586-1", "uniprot_id": "MB212_HUMAN", "id": "Q9Y586-1", "name": "Protein mab-21-like 2", "aln": "------MIAAQAKLVYQLNKYYTERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMIADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQ---SSAESDAWVLQFGEAENRLLMGGCRNKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALESAAKQTWRLAREILTNPKSLDKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8UUZ1-1", "uniprot_id": "MB212_DANRE", "id": "Q8UUZ1-1", "name": "Protein mab-21-like 2", "aln": "------MIATQAKLVYQLNKYYNERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEGMEVIAPNEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQ---SSAESDAWVLQFAEAENRLLMSGCRKKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALETAAKQTWRLAREILTNAKSLDKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y106-1", "uniprot_id": "MB21L_DROME", "id": "Q9Y106-1", "name": "Protein mab-21-like", "aln": "MLVPPDMMAAQTRMVYQMNRFCTERVQARMYKTATAIREICKIVQDILKEVELQEPRFISSLVECNGRFEGVEVISPNEFEIVLYLNQMGVFNFVDDGTLPGCAVLKLSDGRKRSMSLWVEFITASGYLSSRKIRARFQTLVAQACDKSVYRDMVKMVGDTSEVKLRIRERFVVQITPAFKCSGIWPRSAAHWPVPHLPWPHPNIVAEVKTEGFDLLSKESVIMQNKNNNAASMEGDAWVLSFFEAENRLLQGGCRRRCLSMLKTLRDRHLDLPGNPISAYHLKNLLLYECEKHPRDFEWDEGCIADRINGIFLQLISCLQYRRCPHYFLPALDMFKGKSPSALEQAAKQVWRLTRELLTNANAFEKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9U3W6-1", "uniprot_id": "MAB21_DROME", "id": "Q9U3W6-1", "name": "Protein mab-21", "aln": "MLVPSDMIAAQSKMVYQMNKYCADRVQVRKAQIHKQIQEVCRIVQDVLKEVEVQEPRFISSLNDYNGRFQGLEVISPTEFEIIIYLNQMGVLNFVDDGTLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQACDKCAYRDIVKMIADTTEVKLRIRERIIVQITPAFKCAGLWPRSASHWPLPGIPWPHPNIVAEVKTEGFNMLSKECIALQGKN---SAMEGDAWVLSFTDAENRLLQGASRRRCLSILKTLRDRHLDLPGNPVTSYHLKTLLLYECEKHPREMEWEENCIADRINGIFLQLISCLQCRRCPHYFLPNMDLFKGKSPGALENAAKQVWRLTRIMLTNVRCLEEL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*:*:::***:*:: :* *.* . *:*:*::*.*:*****:********* : :.*::*:***:*.***:::*******:******:*******************************:****:********* **. ***:***:.**:********* :*********:*:*****::**:* :*** ** *****:***::****. : .*: :: *.*****.* :****** ...*.:***:*********:***:*:. **:*.***********: :*:* *:.**:***:******** ********* :*:*:**. .*** ****.***:* :*** ..:::*", "identical_positions": 238, "similar_positions": 89, "identity": "64.67%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011102-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99JA8-1", "uniprot_id": "NGB_RAT", "id": "Q99JA8-1", "name": "Neuroglobin", "aln": "MERPESE---LIRQSWRAVSRSPLEHGTVLFSRLFALEPSLLPLFQYNGRQFSSPEDCLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLATLGRKHRAVGVRLSSFSTVGESLLYMLEKCLGPDFTPATRTAWSQLYGAVVQAMSRGWD--GE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER97-1", "uniprot_id": "NGB_MOUSE", "id": "Q9ER97-1", "name": "Neuroglobin", "aln": "MERPESE---LIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSPEDCLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVRLSSFSTVGESLLYMLEKCLGPDFTPATRTAWSRLYGAVVQAMSRGWD--GE----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPG2-1", "uniprot_id": "NGB_HUMAN", "id": "Q9NPG2-1", "name": "Neuroglobin", "aln": "MERPEPE---LIRQSWRAVSRSPLEHGTVLFARLFALEPDLLPLFQYNCRQFSSPEDCLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLASLGRKHRAVGVKLSSFSTVGESLLYMLEKCLGPAFTPATRAAWSQLYGAVVQAMSRGWD--GE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90YJ2-1", "uniprot_id": "NGB_DANRE", "id": "Q90YJ2-1", "name": "Neuroglobin", "aln": "MEKLSEKDKGLIRDSWESLGKNKVPHGIVLFTRLFELDPALLTLFSYSTNCGDAP-ECLSSPEFLEHVTKVMLVIDAAVSHLDDLHTLEDFLLNLGRKHQAVGVNTQSFALVGESLLYMLQSSLGPAYTTSLRQAWLTMYSIVVSAMTRGWAKNGEHKSN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: . : ***:**. :.:. : ** ***:*** *:* **.**.*. . .:* :********:*: **********::::** :**::* .*****:****. .**: *********:..*** :*.: * ** :*. **.**:*** ** ", "identical_positions": 84, "similar_positions": 43, "identity": "52.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011105-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62074-1", "uniprot_id": "KPCI_MOUSE", "id": "Q62074-1", "name": "Protein kinase C iota type", "aln": "---MP--TQRDSSTMSHTVACGGGGDHSHQVRVKAYYRGDIMITHFEPSISFEGLCSEVRDMCSFDNEQPFTMKWIDEEGDPCTVSSQLELEEAFRLYELNKDSELLIHVFPCVPERPGMPCPGEDKSIYRRGARRWRKLYCANGHTFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHKKCHKLVTIECGRHSLPPEPMMPMDQT-MHPDHTQTVIPYNPSSHESLDQVGEEKEAMNTRESGKASSSLG------LQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNFDSQFTNEPVQLTPDDDDIVRKIDQSEFEGFEYINPLLMSAEECV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M7Y5-1", "uniprot_id": "KPCI_RAT", "id": "F1M7Y5-1", "name": "Protein kinase C iota type", "aln": "---MP--TQRDSSTMSHTVACGGGGDHSHQVRVKAYYRGDIMITHFEPSISFEGLCSEVRDMCSFDNEQPFTMKWIDEEGDPCTVSSQLELEEAFRLYELNKDSELLIHVFPCVPERPGMPCPGEDKSIYRRGARRWRKLYCANGHTFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHKKCHKLVTIECGRHSLPPEPMMPMDQSSMHPDHTQTVIPYNPSSHESLDQVGEEKEAMNTRESGKASSSLG------LQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNFDSQFTNEPVQLTPDDDDIVRKIDQSEFEGFEYINPLLMSAEECV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41743-1", "uniprot_id": "KPCI_HUMAN", "id": "P41743-1", "name": "Protein kinase C iota type", "aln": "---MP--TQRDSSTMSHTVAGGGSGDHSHQVRVKAYYRGDIMITHFEPSISFEGLCNEVRDMCSFDNEQLFTMKWIDEEGDPCTVSSQLELEEAFRLYELNKDSELLIHVFPCVPERPGMPCPGEDKSIYRRGARRWRKLYCANGHTFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHKKCHKLVTIECGRHSLPQEPVMPMDQSSMHSDHAQTVIPYNPSSHESLDQVGEEKEAMNTRESGKASSSLG------LQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNFDSQFTNEPVQLTPDDDDIVRKIDQSEFEGFEYINPLLMSAEECV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90XF2-1", "uniprot_id": "KPCI_DANRE", "id": "Q90XF2-1", "name": "Protein kinase C iota type", "aln": "---MP--TLRDS-TMSHP------GENPHQVRVKAYYRGDIMITHFEPSISYEGLCNEVRDMCSMDNDQLFTMKWIDEEGDPCTVSSQLELEEALRLYELNKDSELIIHVFPCVPEKPGMPCPGEDKSIYRRGARRWRKLYYATGHAFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHKKCHKLVTVECGRQVIQDPMIGRIDPGSTHPEHPDQVLGKK-NSTESINHEGEEHEAVGSRESGKAVSSLG------LIDFDLLRVIGRGSYAKVLLVRLKKTERIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKGFLNKESKERLGCHPQTGFADIMAHPFFRNVDWDLMEQKQVVPPFKPNISGEFGLDNFDAQFTNEPIQLTPDDDDAVKKIDQSEFEGFEYINPLLMSAEECV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9X0-1", "uniprot_id": "APKC_DROME", "id": "A1Z9X0-1", "name": "Atypical protein kinase C", "aln": "MQKMPSQILNDGSSVSLNSASMNMANTPNSITVKTAYNGQIIITTINKNISYEELCYEIRNICRFPLDQPFTIKWVDEENDPCTISTKMELDEAIRLYEMNFDSQLVIHVFPNVPQAPGLSCDGEDRSIYRRGARRWRKLYRVNGHIFQAKRFNRRAFCAYCQDRIWGLGRQGFKCIQCKLLVHKKCHKLVQKHCTDQPEP-LVKERAEESSDPIPVPLPPLPYEAMSGGAEACETHDHAHIVAPPPPEDPLEPGTQRQYSLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFETASNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVLKGFLNKNPADRLGCHRESAFMDIVSHPFFKNMDWELLERKQVTPPFKPRLDSDRDLANFPPEFTGEAVQLTPDDDHVIDNIDQSEFEGFEYVNPLLMSLEDCV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** .*. ::* .: .:.: **: *.*:*:** :: .**:* ** *:*::* : :* **:**:***.****:*:::**:**:****:* **:*:***** **: **:.* ***:************** ..** **********.** * **********:***:************* .* : : . : : * : .:: : : . : . * * **:*:************:*.*::* *******:** **.**************** **************** ********:*.*****:******:*********:********:***:*************** ***************:**************************************::**:*******:.*:*:***************** *********:******.****:. :***** ::.* ** .****:*:**:::*:***.*****.:..: .* ** .:**.*.:*******. : :***********:****** *:**", "identical_positions": 389, "similar_positions": 114, "identity": "64.09%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011109-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ET58-1", "uniprot_id": "KLF2_RAT", "id": "Q9ET58-1", "name": "Krueppel-like factor 2", "aln": "MALSEPILPSFATFASPC-ERGLQERWPRNEPEAG-----------------STDEDLNSVLD--FILS--MGLDGLGAENP-----PEPPPQPPPPAFYYPE--PGAPPPYGTPAAGLGTELLRPDLDAPQGPALHGRFLLAPP------GRLVKAEPPEVDGGG-YGCAAGLARGPRGLKLEGALGATGACMRGPAGRPPPPSDTPPLSPDGPPRLPAPGPRNPFPPPFGPGPSFGGPGP-ALHYGPPAPGAFGLFDD---AAAALGLAPPATRGLLTPPSSPLELLEAKPKRGRRSWPRKRAATHTCSYTNCGKTYTKSSHLKAHLRTHTGEKPYHCNWDGCGWKFARSDELTRHYRKHTGHRPFQCHLCDRAFSRSDHLALHMKRHM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60843-1", "uniprot_id": "KLF2_MOUSE", "id": "Q60843-1", "name": "Krueppel-like factor 2", "aln": "MALSEPILPSFATFASPC-ERGLQERWPRNEPEAG-----------------GTDEDLNNVLD--FILS--MGLDGLGAENP-----PEPPPQPPPPAFYYPE--PGAPPPYSIPAASLGTELLRPDLDPPQGPALHGRFLLAPP------GRLVKAEPPEVDGGG-YGCAPGLAHGPRGLKLEGAPGATGACMRGPAGRPPPPPDTPPLSPDGPLRIPASGPRNPFPPPFGPGPSFGGPGP-ALHYGPPAPGAFGLFEDAAAAAAALGLAPPATRGLLTPPSSPLELLEAKPKRGRRSWPRKRAATHTCSYTNCGKTYTKSSHLKAHLRTHTGEKPYHCNWEGCGWKFARSDELTRHYRKHTGHRPFQCHLCDRAFSRSDHLALHMKRHM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5W3-1", "uniprot_id": "KLF2_HUMAN", "id": "Q9Y5W3-1", "name": "Krueppel-like factor 2", "aln": "MALSEPILPSFSTFASPCRERGLQERWPRAEPESG-----------------GTDDDLNSVLD--FILS--MGLDGLGAEAA-----PEPPPPPPPPAFYYPE--PGAPPPYSAPAGGLVSELLRPELDAPLGPALHGRFLLAPP------GRLVKAEPPEADGGGGYGCAPGLTRGPRGLKREGAPGPAASCMRGPGGRPPPPPDTPPLSPDGPARLPAPGPRASFPPPFG-GPGFGAPGP-GLHYAPPAPPAFGLFDDAAAAAAALGLAPPAARGLLTPPASPLELLEAKPKRGRRSWPRKRTATHTCSYAGCGKTYTKSSHLKAHLRTHTGEKPYHCNWDGCGWKFARSDELTRHYRKHTGHRPFQCHLCDRAFSRSDHLALHMKRHM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LXI7-1", "uniprot_id": "Q1LXI7_DANRE", "id": "Q1LXI7-1", "name": "", "aln": "MALSGTILPSISTFSAQK-EKCWENRWKDELDRSMHLSCIADLSNMDNLNRITDDEDLDKYLDLEFILANTAGSDNLGLGMAGDYRMQESRNMYNPTTYSVPEINPSPPPPYTT---SLMAELLQSDIDTYCQPSLQGRFLVRPAFPTQDISECIKVEPCMDSYGPVRGMVPKVKQEGNGACMRSYEQPRLANSPQGAGSMTPPQSPAELINTDCQSHSQMCHALTFSQSYQGNTGFPHAAPPQMQLPYQSTHHFSMCDD------GLAMPNANQRVLLTPPSSPLEL-DAKPKRGRRTWPRKRTATHTCTFSGCGKTYTKSSHLKAHHRTHTGEKPYHCSWEGCGWKFARSDELTRHFRKHTGHRPFQCHLCERAFSRSDHLALHMKRHM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** .****::**:: *: ::** .: *:**:. ** ***: * *.** . *. *.:: ** *..**** .* :***:.::*. *:*:****: *. .. :*.** . * * .. : : .* .. . : .* .** ... * . . .*. .: ...* ..* :: :. *.: :* .*.:. . * *****:***** :********:*****:*****:::.************** ***********.*:***************:**************:*****************", "identical_positions": 163, "similar_positions": 87, "identity": "41.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011115-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61983-1", "uniprot_id": "1433G_RAT", "id": "P61983-1", "name": "14-3-3 protein gamma", "aln": "--MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDG--GEGNN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61982-1", "uniprot_id": "1433G_MOUSE", "id": "P61982-1", "name": "14-3-3 protein gamma", "aln": "--MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDG--GEGNN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61981-1", "uniprot_id": "1433G_HUMAN", "id": "P61981-1", "name": "14-3-3 protein gamma", "aln": "--MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDG--GEGNN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PC29-1", "uniprot_id": "143G1_DANRE", "id": "Q6PC29-1", "name": "14-3-3 protein gamma-1", "aln": "--MVDREQLVQKARLAEQAERYDDMAAAMKSVTELNEALSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELETVCQDVLNLLDNFLIKNCGETQHESKVFYLKMKGDYYRYLAEVATGEKRAAVVESSEKSYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDEG--GEGNN-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P29310-1", "uniprot_id": "1433Z_DROME", "id": "P29310-1", "name": "14-3-3 protein zeta", "aln": "MSTVDKEELVQKAKLAEQSERYDDMAQAMKSVTETGVELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTEAS--ARKQQLAREYRERVEKELREICYEVLGLLDKYLIPKASNP--ESKVFYLKMKGDYYRYLAEVATGDARNTVVDDSQTAYQDAFDISKGKMQPTHPIRLGLALNFSVFYYEILNSPDKACQLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDTQGDEAEPQEGGDN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:*:*****:****:******* ***.*** . **********************************.*. :* ::.* ***::****. :* :**.***::** :..:. ***********************: * :**:.*:.:*.:*.:*** :**************:******* *:*::**:*** ************************************* *.*:. **.: ", "identical_positions": 178, "similar_positions": 47, "identity": "70.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011116-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P57682-1", "uniprot_id": "KLF3_HUMAN", "id": "P57682-1", "name": "Krueppel-like factor 3", "aln": "MLMFDPVP---------VKQEAMDPVSVSYPSNYMESMKPNKYGVIYSTPLPEKFFQTPEGLSHGIQMEPVDLTVNKRSSPPSAGNSPSSLKFPSSHRRASPGLSMPSSSPPIKKYSPPSPGVQP--FGVPLSMPPVMAAALSRHGIRSPGILPVIQPVVVQPVPFMYTSHLQQPLMVSLSEEMENSSSSMQVPVIESYEKPISQKKIKIEPGIEPQRTDYYPEEMSPPLMNSVSPPQALLQENHPSVIVQPGKRPLPVESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A4V3-1", "uniprot_id": "D4A4V3_RAT", "id": "D4A4V3-1", "name": "", "aln": "MLMFDPVP---------VKQEAMDPVTVSYPSNYIESMKPNKYGVIYSTPLPDKFFQTPEGLAHGIQMEPVDLTVNKRGSPPSAAGSPSSLKFP-SHRRASPGLSMPSSSPPIKKYSPPSPGVQP--FGVPLSMPPVMAAALTRHGIRSPGILPVIQPVVVQPVPFMYTSHLQQPLMVSLSEEMDNSNSGMPVPVIESYEKPILQKKIKIEPGIEPQRTDYYPEEMSPPLMNSVSPPQALLQENHPSVIVQPGKRPLPVESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60980-1", "uniprot_id": "KLF3_MOUSE", "id": "Q60980-1", "name": "Krueppel-like factor 3", "aln": "MLMFDPVP---------VKQEAMDPVSVSFPSNYIESMKPNKYGVIYSTPLPDKFFQTPEGLTHGIQVEPVDLTVNKRGSPPAAGGSPSSLKFP-SHRRASPGLSMPSSSPPIKKYSPPSPGVQP--FGVPLSMPPVMAAALSRHGIRSPGILPVIQPVVVQPVPFMYTSHLQQPLMVSLSEEMDNSNSGMPVPVIESYEKPLLQKKIKIEPGIEPQRTDYYPEEMSPPLMNPVSPPQALLQENHPSVIVQPGKRPLPVESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCDRSFSRSDHLALHRKRHMLV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2BG67-1", "uniprot_id": "A2BG67_DANRE", "id": "A2BG67-1", "name": "", "aln": "MLTCDPKPDMSLYQPYSTLIKSHETFGMVLPPAVVSGAHLYPSHYHPSYQLPYSHRQSQD--VHQAQIEPVDLSIGNKSS----GSSPSSSLAS-SSPRASP----PS---PYEAHSPASRCSQNRQLSPSLTLPIPAVTQVLTPFVSSPGMIPVIP--MPLSVLYPPSLHLSPSIIISPVTPEDPAN-HKHFSVIKS------ENTSDHHELLKPIKSEPHPEHTQDNHSQEKSVITALPNYNDRGNTQSP-----KVESPDLLKKRRIHRCDFNGCNKVYTKSSHLKAHRRTHTGEKPYKCMWEGCTWKFARSDELTRHYRKHTGVKPFHCPDCDRTFSRSDHLALHKKRHLLV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ** * . :: :.. : *. :.. : * ** .. *: : * *:*****::.::.* ..**** . * **** ** * : :**.* * :. .*::* .: : : ***::*** : .* : : **. .:::* : :. ..**:* ::. . . ::* ::: :**. . : * ** : *. . .* ***** :********::*************************** *****************:*****:***:******:**********:***:**", "identical_positions": 143, "similar_positions": 82, "identity": "40.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011128-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P78504-1", "uniprot_id": "JAG1_HUMAN", "id": "P78504-1", "name": "Protein jagged-1", "aln": "---------------------------------------------------MRSPRTRGRSGRPLSLLLALLCALRAKVCGASGQFELEILSMQNVNGELQNGNCCGG-ARNPGDRKCTRDECDTYFKVCLKEYQSRVTAGGP---CSFGSGSTPVIGGNTFNLK-ASRGNDRNRIVLPFSFAWPRSYTLLVEAWDSSNDTVQ---PDSIIEKASHSGMINPSRQWQTLKQNTGVAHFEYQIRVTCDDYYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICN-EPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLG--------------------------------------------------------------FECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA--------------------------------------------KPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQS--GGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITMG--------------------SVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKG-------HSECPSGQSCIPILDDQCFVHPCTGVGECRSSS---------LQPVKTKCTSDSYYQDNCANITFTFNKEMMSPGLTTEHICSELRNLNILKNVSAEYS--------IYIACEPSPSANNEIHVAISAEDIRDDG-NPIKEITDKIIDLVSK-----------RDGNSSLIAAVAEVRVQRRPLKN--RTDFLVPLLSSVLTVAWICCLVTAFYWCLRKRRKPGS--------HTHSASEDNTTNN-VREQLNQIKNPIEKHGAN------------TVPIK--DYENKNSKMSKIRTHNSEVEEDDMDKHQQKARFAKQPAYTLVDREEKPPNG--TPTKHPNWTNKQDNRDLESAQ------------SLNRMEYIV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QXX0-1", "uniprot_id": "JAG1_MOUSE", "id": "Q9QXX0-1", "name": "Protein jagged-1", "aln": "---------------------------------------------------MRSPRTRGRPGRPLSLLLALLCALRAKVCGASGQFELEILSMQNVNGELQNGNCCGG-VRNPGDRKCTRDECDTYFKVCLKEYQSRVTAGGP---CSFGSGSTPVIGGNTFNLK-ASRGNDRNRIVLPFSFAWPRSYTLLVEAWDSSNDTIQ---PDSIIEKASHSGMINPSRQWQTLKQNTGIAHFEYQIRVTCDDHYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPDCNKAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGTCN-EPWQCLCETNWGGQLCDKDLNYCGTHQPCLNRGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSSG--------------------------------------------------------------FECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA--------------------------------------------KPCVNARSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTTCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQS--GGKFTCDCNKGFTGTYCHENINDCESNPCKNGGTCIDGVNSYKCICSDGWEGAHCENNINDCSQNPCHYGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEVDTFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGDSFTCVCKEGWEGPICTQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYQCICPPGHSGAKCHEVSGRSCITMG--------------------RVILDGAKWDDDCNTCQCLNGRVACSKVWCGPRPCRLHKS-------HNECPSGQSCIPVLDDQCFVRPCTGVGECRSSS---------LQPVKTKCTSDSYYQDNCANITFTFNKEMMSPGLTTEHICSELRNLNILKNVSAEYS--------IYIACEPSLSANNEIHVAISAEDIRDDG-NPVKEITDKIIDLVSK-----------RDGNSSLIAAVAEVRVQRRPLKN--RTDFLVPLLSSVLTVAWVCCLVTAFYWCVRKRRKPSS--------HTHSAPEDNTTNN-VREQLNQIKNPIEKHGAN------------TVPIK--DYENKNSKMSKIRTHNSEVEEDDMDKHQQKVRFAKQPVYTLVDREEKAPSG--TPTKHPNWTNKQDNRDLESAQ------------SLNRMEYIV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q90Y57-1", "uniprot_id": "JAG1A_DANRE", "id": "Q90Y57-1", "name": "Protein jagged-1a", "aln": "------------------------------------------------------MILRPSATFAALSAHVLLRCLWMRVCEASGHFEMQVLSMQNVNGELQSGACCDG-ARDPAERSCAADQCDTFFRVCLKEYQSRVSSGGP---CSYGSGSTPVIGGNTFSVKPLDQTNDKTRIVLPFSFAWPRSYTLIVEALDFNNDSSTGSINGQVIEKAVQSGMINPNRQWQVLKHNGPVAQFQYQIRVTCDEHYFGFGCNKFCRPRDDFFGHYTCDHNGNKTCLEGWAGPECNTAICKQGCSIEHGSCKVPGNCRCLYGWQGEYCDQCIPHPGCVHGTCI-EPWQCLCDTNWGGQLCDKDLNTCGTLQPCLNGGTCSNTGPDKYHCACPDGYSGQNCERADNACLSEPCLNGGLCVESSLG--------------------------------------------------------------FECQCAAGWTGPSCNINEDDCSPNPCNHSGVCVDLVDGFKCICPVQWTGKTCLIDANECEE--------------------------------------------SPCVNAHSCRNLIGGYFCECLPGWTGQNCDINVNDCHGQCLNGGLCKDLVNGYRCVCAAGFAGDRCERDVDECASRPCLNGGRCQDTLNGFQCLCPPGFSGATCQLDLDYCESGPCQNGAQCFSLASDYYCKCPEDYEGKNCSQLKDHCLITPCQVIDSCTVAVVSNSTPGGLRLISSSVCGPHGRCRSHSHAGGHFSCDCQDGFTGTYCHENINDCESSPCLSGGTCIDKINAYQCICADGWEGPNCETNIDDCRTNPCRDRGVCRDLVNDFYCECENGWKGKTCHSRESQCDEDTCNNGGTCSDEGDSFKCLCSPGWEGATCNIAKNSSCLPNPCENGATCVVTGDGFTCVCKEGWEGPTCSQNSNDCNPQPCYNSGTCVDGDNWYRCECASGFAGPDCRININECQSSPCAFGSTCVDEINGYRCLCPPGRTGPRCQEVTGRPCVIGG--------------------RIAVDGAKWAEDCNTCYCHKGIVTCTKLFCGPKACRMLGSG------RGDCPTGQLCVPVRDEQCFVKPCSSQGECWSAH---------RPAVRTHCQPDS----HCANVTFTFNKDTMPQGVTVEQVCRELRHLYVTKNVTSEFS--------ISVSCELSSAASNEIHVAIHVTENGIHGRVPVKEITDNIIDLVSK-----------HSANSSVIGSIAEVRVQRKQPQNP-NVDYMVPLLVSVVTAIWVLALASVFLWCIRHHRKQSSSATAINPTSPFSTPEENTANN-AREHLNQIKNHIEKNASNG-----------SLPGKELHCDDKNTVNAKIRTQFPES---DASRRLQKTRFPHQPAYMLVDRDDRLSSNGTDIKKHPQWTNKRDNRDLESQHRVPDSQHRDSQHSLQKMEYIV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18168-1", "uniprot_id": "SERR_DROME", "id": "P18168-1", "name": "Protein serrate", "aln": "MYKMFRKHFRRKPATSSSLESTIESADSLGMSKKTATKRQRPRHRVPKIATLPSTIRDCRSLKSACNLIALILILLVHKISAAGNFELEILEISNTNSHLLNGYCCGMPAELRATKTIGCSPCTTAFRLCLKEYQTTEQGASISTGCSFGNATTKILGGSSFVLS----DPGVGAIVLPFTFRWTKSFTLILQALDMYNTSYP--DAERLIEETSYSGVILPSPEWKTLDHIGRNARITYRVRVQCAVTYYNTTCTTFCRPRDDQFGHYACGSEGQKLCLNGWQGVNCEEAICKAGCDPVHGKCDRPGECECRPGWRGPLCNECMVYPGCKHGSCNGSAWKCVCDTNWGGILCDQDLNFCGTHEPCKHGGTCENTAPDKYRCTCAEGLSGEQCEIVEHPCATRPCRNGGTCTLKTSNRTQAQVYRTSHGRSNMGRPVRRSSSMRSLDHLRPEGQALNGSSSPGLVSLGSLQLQQQLAPDFTCDCAAGWTGPTCEINIDECAGGPCEHGGTCIDLIGGFRCECPPEWHGDVCQVDVNECEAPHSAGIAANALLTTTATAIIGSNLSSTALLAALTSAVASTSLAIGPCINAKECRNQPGSFACICKEGWGGVTCAENLDDCVGQCRNGATCIDLVNDYRCACASGFKGRDCETDIDECATSPCRNGGECVDMVGKFNCICPLGYSGSLCEEAKENCTPSPCLEG-HCLNTPEGYYCHCPPDRAGKHCEQLRPLCSQPPCNEGCFANVSLATSATTTTTTTTTATTTRKMAKP------------------------------SGLPCSGHGSCEMSDVGTFCKCHVGHTGTFCEHNLNECSPNPCRNGGICLDGDGDFTCECMSGWTGKRCSERATGCYAGQCQNGGTCMPG-------------------APDKALQP----------------HCRCAPGWTGLFCAEAIDQCRGQPCHNGGTCESGAGWFRCVCAQGFSGPDCRINVNECSPQPCQGGATCIDGIGGYSCICPPGRHGLRCEILLSDPKSACQNASNTISPYTALNRSQNWLDIALTGRTEDDENCNACVCENGTSRCTNLWCGLPNCYKVDPLSKSSNLSGVCKQHEVCVPALSETCLSSPCNVRGDCRALEPSRRVAPPRLPAKSSCWPNQAVVNENCARLTILLALERVGKGASVEGLCSLVRVLLAAQLIKKPASTFGQDPGMLMVLCDLKTGTNDTVELTVSSSKLNDPQLPVAVGLLGELLSFRQLNGIQRRKELELQHAKLAALTSIVEVKLETARVADGSGHSLLIGVLCGVFIVLVGFSVFISLYWKQRLAYRTSSGMNLTPSLDALRHEEEKSNNLQNEENLRRYTNPLKGSTSSLRAATGMELSLNPAPELAASAASSSALHRSQPLFPPCDFERELDSSTGLKQAHKRSSQILLHKTQNSDMRKNTVGSLDSPRKDFGKRSINCKSMPPSSGDEGS--DVLATTVMV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .*: * : *:*:**:::*.:.*.*..* .* **. .. . :. . * * *::******: ... **:*..:* ::**.:* :. . *****:* *.:*:**:::* * * : :**:: **:* *. :*:.*.: *:: *::** * *:. *..******* ****:*. :*:* *::** * :*: ***: **. **.*. **:*.* **:* *::*: :*** ** * ..*:*:*:***** ***:*** *** :** : ***.**.****:*:*.:* ** :** .::.* : ** * * * .: . * *:*:.*****:*. * *:*: . *.*.*.* **:.**:* ** :* *..* :*.**** **:**:.*:* ..: * * ** * .* *::** *** *.. * ****.*** *..*: * ** *:****: ** ***.* : :. *:*:** *:** *: : * ..** :* :* . ...*:*:** * **:*.:*: * ..*: ..*::.:. *. ::.. .: .. ** . *:* . * * * *. ** *:::* ***: * * * .** *:* .**.** * .* : * *:***** * :.: * * * ** * *:: ::* :**:*.*** .* .*:** ** **:*******:***...** *:**:* *.** *:****: * :*. : . . . :: ::**:* * :* *::::** * . * : *:* .: *: **. *:* : . : :: :**.:*: : : : * :.* :* :* * : :. * : : *: . .:.: :.::: . : .:::.: . : .: : : ::.**::: : . :: :* .*. . .: : * * : .* . *::: * .*:*.: .* :: :. . * ...: . . : . : ::. *:.: :. . . :. .:*.::. .: :*", "identical_positions": 367, "similar_positions": 359, "identity": "24.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011128-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63722-1", "uniprot_id": "JAG1_RAT", "id": "Q63722-1", "name": "Protein jagged-1", "aln": "---------------------------------------------------MRSPRTRGRPGRPLSLLLALLCALRAKVCGASGQFELEILSMQNVNGELQNGNCCGG-ARNPGDRKCTRDECDTYFKVCLKEYQSRVTAG---GPCSFGSGSTPVIGGNTFNLKASRGNDRNRIVLPFSFAWPRSYTLLVEAWDSSNDTIQ-PDSIIEKASHSGMINPSRQWQTLKQNTGIAHFEYQIRVTCDDHYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPECNKAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGTCN-EPWQCLCETNWGGQLCDKDLNYCGTHQPCLNRGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSSG--------------------------------------------------------------FECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA--------------------------------------------KPCVNARSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSESGGKFTCDCNKGFTGTYCHENINDCEGNPCTNGGTCIDGVNSYKCICSDGWEGAHCENNINDCSQNPCHYGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCY----DEVDTFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGDSFTCVCKEGWEGPICTQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYQCICPPGHSGAKCHEVSGRSCITMGRVILDGAKWDDDCNTCQCLNGRVACSKVWCGPRPCR----LHKG---HGECPNGQSCIPVLDDQCFVRPCTGAGECRSSS---------LQPVKTKCTSDSYYQDNCANITFTFNKEMMSPGLTTEHICSELRNLN---ILKNVSAEYS-----IYIACEPSLSANNEIHVAISAEDIRDDGNPVKE------ITDKIIDLVSKR------DGNSSLIAAVAEVRVQ--RRPLKNRTDFLVPLLSSVLTVAWVCCLVTAFYWCVRKRRRKPSSHT------HSAPEDNTTNNVR--EQLNQIKNPIEKHGANTVPIKDYE---NKNSKMSKIRTHNSEVE-----------EDDMDKHQQKVRFAKQPVYTLVDREEK------------VPQRTPTKHPNWTNKQDNRDLESAQSLNRMEYIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXX0-1", "uniprot_id": "JAG1_MOUSE", "id": "Q9QXX0-1", "name": "Protein jagged-1", "aln": "---------------------------------------------------MRSPRTRGRPGRPLSLLLALLCALRAKVCGASGQFELEILSMQNVNGELQNGNCCGG-VRNPGDRKCTRDECDTYFKVCLKEYQSRVTAG---GPCSFGSGSTPVIGGNTFNLKASRGNDRNRIVLPFSFAWPRSYTLLVEAWDSSNDTIQ-PDSIIEKASHSGMINPSRQWQTLKQNTGIAHFEYQIRVTCDDHYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPDCNKAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGTCN-EPWQCLCETNWGGQLCDKDLNYCGTHQPCLNRGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSSG--------------------------------------------------------------FECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA--------------------------------------------KPCVNARSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTTCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCKNGGTCIDGVNSYKCICSDGWEGAHCENNINDCSQNPCHYGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCY----DEVDTFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGDSFTCVCKEGWEGPICTQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYQCICPPGHSGAKCHEVSGRSCITMGRVILDGAKWDDDCNTCQCLNGRVACSKVWCGPRPCR----LHKS---HNECPSGQSCIPVLDDQCFVRPCTGVGECRSSS---------LQPVKTKCTSDSYYQDNCANITFTFNKEMMSPGLTTEHICSELRNLN---ILKNVSAEYS-----IYIACEPSLSANNEIHVAISAEDIRDDGNPVKE------ITDKIIDLVSKR------DGNSSLIAAVAEVRVQ--RRPLKNRTDFLVPLLSSVLTVAWVCCLVTAFYWCVRKRR-KPSSHT------HSAPEDNTTNNVR--EQLNQIKNPIEKHGANTVPIKDYE---NKNSKMSKIRTHNSEVE-----------EDDMDKHQQKVRFAKQPVYTLVDREEK------------APSGTPTKHPNWTNKQDNRDLESAQSLNRMEYIV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78504-1", "uniprot_id": "JAG1_HUMAN", "id": "P78504-1", "name": "Protein jagged-1", "aln": "---------------------------------------------------MRSPRTRGRSGRPLSLLLALLCALRAKVCGASGQFELEILSMQNVNGELQNGNCCGG-ARNPGDRKCTRDECDTYFKVCLKEYQSRVTAG---GPCSFGSGSTPVIGGNTFNLKASRGNDRNRIVLPFSFAWPRSYTLLVEAWDSSNDTVQ-PDSIIEKASHSGMINPSRQWQTLKQNTGVAHFEYQIRVTCDDYYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICN-EPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLG--------------------------------------------------------------FECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA--------------------------------------------KPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCY----DEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCL----LHKG---HSECPSGQSCIPILDDQCFVHPCTGVGECRSSS---------LQPVKTKCTSDSYYQDNCANITFTFNKEMMSPGLTTEHICSELRNLN---ILKNVSAEYS-----IYIACEPSPSANNEIHVAISAEDIRDDGNPIKE------ITDKIIDLVSKR------DGNSSLIAAVAEVRVQ--RRPLKNRTDFLVPLLSSVLTVAWICCLVTAFYWCLRKRR-KPGSHT------HSASEDNTTNNVR--EQLNQIKNPIEKHGANTVPIKDYE---NKNSKMSKIRTHNSEVE-----------EDDMDKHQQKARFAKQPAYTLVDREEK------------PPNGTPTKHPNWTNKQDNRDLESAQSLNRMEYIV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90Y54-1", "uniprot_id": "JAG1B_DANRE", "id": "Q90Y54-1", "name": "Protein jagged-1b", "aln": "---------------------------------------------------MILRRS---SVFSAFYLHAFLLCLRTTVSDASGHFELEILSMQNANGELQNGACCDG-ARNPADRKCTRDECDTYFKVCLKEYQSRVSSA---GACSFGTGSTPVLGGNKFSTKGTR-SEKSRIVLPFSFAWPRSYTLIVEALDFNNETASESGKLIEKAYHSGMINPNRQWQRLTHNGPVAQFEYQIRVTCLEHYYGFGCNKFCRPRDEFFGHYTCDQNGNKTCLEGWTGPDCNTAICRQGCSTEHGSCKQPGGCKCLYGWQGPYCDKCIPHPGCVHGTCV-EPWQCLCDTNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCEDGYSGVNCERAEHACLSNPCANGGTCKETSQG--------------------------------------------------------------YECHCAIGWSGTSCEINVDDCTPNQCKHGGTCQDLVNGFKCACPPHWTGKTCQIDANECED--------------------------------------------KPCVNAKSCHNLIGAYFCECLPGWSGQNCDININDCKGQCLNGGTCKDLVNGYRCLCPPGYTGEQCEKDVDECASSPCLNGGRCQDEVNGFQCLCPAGFSGQLCQLDIDYCKPNPCQNGAQCFNLASDYFCKCPDDYEGKNCSHLKDHCRTTSCQVIDSCTVAVASNSTPEGVRYISSNVCGPHGRCRSQAGGQFTCECQEGFRGTYCHENINDCESNPCRNGGTCIDKVNVYQCICADGWEGVHCEINIDDCSLNPCLNKGACQDLVNDFYCECRNGWKGKTCHSRDSQCDEATCNNGGTCH----DEGDTFKCRCSPGWEGATCNIAKNSSCLPNPCENGGTCVVNGDSFNCVCKEGWEGSTCTENTNDCNPHPCYNSGTCVDGENWYRCECAPGFAGPDCRININECQSSPCAFGSTCVDEINGYRCLCPPGRIGPDCQEVVGRPCIANGQVTADGAKWEEDCNICQCQNGRIHCTMMWCGPKSCR----IGKA---RGGCPASQSCVPIKEEQCFVKPCPSLGECWPSA---------PPPPSKCHASFSYQDDSCANITFTFNKENMPQGLSVEHVCNELRHWY---LLKNLSTEYA-----VSISCEPSSSASNEIHISISTEEPRTDRSPIKD------ITVQIIDLVSKH------NGNSTIIKAITGVRVH--QIPSP-KTDYLVPLLSSIFIVLWIFALASAFLWCIHRRR-KQNTHSNT---ATSATEDNTTNNVR--EQLNQIKNPIEKHAAHGVPIKDYE---GKNSIIAKIRTHNSEVE-----------EEDMDKHLQKARFTKQPAYTLVEREER------------APN----KNPNWTNKQDNRDLETAQSLNRMEYIV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18168-1", "uniprot_id": "SERR_DROME", "id": "P18168-1", "name": "Protein serrate", "aln": "MYKMFRKHFRRKPATSSSLESTIESADSLGMSKKTATKRQRPRHRVPKIATLPSTIRDCRSLKSACNLIALILILLVHKISAAGNFELEILEISNTNSHLLNGYCCGMPAELRATKTIGCSPCTTAFRLCLKEYQTTEQGASISTGCSFGNATTKILGGSSFVLSDPG---VGAIVLPFTFRWTKSFTLILQALDMYNTSYPDAERLIEETSYSGVILPSPEWKTLDHIGRNARITYRVRVQCAVTYYNTTCTTFCRPRDDQFGHYACGSEGQKLCLNGWQGVNCEEAICKAGCDPVHGKCDRPGECECRPGWRGPLCNECMVYPGCKHGSCNGSAWKCVCDTNWGGILCDQDLNFCGTHEPCKHGGTCENTAPDKYRCTCAEGLSGEQCEIVEHPCATRPCRNGGTCTLKTSNRTQAQVYRTSHGRSNMGRPVRRSSSMRSLDHLRPEGQALNGSSSPGLVSLGSLQLQQQLAPDFTCDCAAGWTGPTCEINIDECAGGPCEHGGTCIDLIGGFRCECPPEWHGDVCQVDVNECEAPHSAGIAANALLTTTATAIIGSNLSSTALLAALTSAVASTSLAIGPCINAKECRNQPGSFACICKEGWGGVTCAENLDDCVGQCRNGATCIDLVNDYRCACASGFKGRDCETDIDECATSPCRNGGECVDMVGKFNCICPLGYSGSLCEEAKENCTPSPCLEG-HCLNTPEGYYCHCPPDRAGKHCEQLRPLCSQPPCNEGCFANVSLATSATTTTT---TTTTATTTRKMAKPSG-------------------------LPCSGHGSCEMSDVGTFCKCHVGHTGTFCEHNLNECSPNPCRNGGICLDGDGDFTCECMSGWTGKRCSERATGCYAGQCQNGGTCMPGAPDKALQPHCRCAPGWTGLFCAEAID-QCRGQPCHNGGTCESGAGWFRCVCAQGFSGPDCRINVNECSPQPCQGGATCIDGIGGYSCICPPGRHGLRCEILLSDPKS-------ACQNASN---TISP--------YTALNRSQNWLDIALTGRTEDDENCNACVCENGTSRCTNLWCGLPNCYKVDPLSKSSNLSGVCKQHEVCVPALSETCLSSPCNVRGDCRALEPSRRVAPPRLPAKSSCWPNQAVVNENCARLTILLALERVGKGASVEGLCSLVRVLLAAQLIKKPASTFGQDPGMLMVLCDLKTGTNDTVELTVSSSKLNDPQLPVAVGLLGELLSFRQLNGIQRRKELELQHAKLAALTSIVEVKLETARVADGSGHSLLIGVLCGVFIVLVGFSVFISLYWKQRLAYRTSSGMNLTPSLDALRHEEEKSNNLQNEENLRRYTNPLKGSTSSLRAATGMELSLNPAPELAASAASSSALHRSQPLFPPCDFERELDSSTGLKQAHKRSSQILLHKTQNSDMRKNTVGSLDSPRKDFGKRSINCKSMPPSSGDEGSDVLATTVMV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . * *:: * . .*:*:******.:.*.*..* ** **. .. . :. . * * *::******: .. ****..:* ::**..* . . . *****:* *.:*:**:::* * * : . :**:: :**:* *. :*: * : *:: *::** * **. *..******: ****:*..:*:* *::** * :*: ***: **.. **.*. ** *.* **:* *::*: :*** ** * ..*:*:*:***** ***:***:****:** : ***.**.****:*:* :* ** :** .**.* : ** * *:*. .: . : *.*: **:*.:*. *:*:*: . *.***** **:.**:* ***.* *..**:*.**** **:**:.*:* .:: * * ** * .* *::** *** *..:* ****.*** *..*: * .** *:****:.** ***.* : :. *:*:** *:**.**: : * *.** :* :* * ...*:*:** * **:*.:*: * ..*: ..*::*:. *. . ::... . : . :* ** . *:* * * * *..** *:::** *** * * * .** *:* .**.** * .* : * . *:***** *: :* *. ** * * * : .* :**.***** .. * *** :*:.*. * *.*:*.*:** ...**:** . * * *.** * *.* :.: :* :* : * :.* . .*. . . . :: :::** * * ** *: :*** * : *. . * : *:* .: *: ** *:* . . .. .. : ::.**.:*: : * : * :.* :*. :* ::*: :: :. : : *: . .:.: :.:::*:.. . *: :: : :: :.:: ..: : : ::. *::. : . . *: :*..:: * .: :: * : . . . *::.:**:: *:*.: .**:: : . .. * . . :: : .* :. * ::*. : *:. *:.: :. * *.. :. . : ...: :*", "identical_positions": 390, "similar_positions": 386, "identity": "26.75%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011128-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZII9-1", "uniprot_id": "D3ZII9_RAT", "id": "D3ZII9-1", "name": "Guanylyl cyclase-activating protein 1", "aln": "MGNVVEGKSVEELSSTECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSPSASQYVEQMFETFDFNKDGYIDFMEYVAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRAIRTINPWSDSSMSAEEFTDTVFAKIDINGDGELSLEEFMEGVQKDQMLLDTLTRSLDLTRIVRRLQNGEQEEAGAGDLAAEAAG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43081-1", "uniprot_id": "GUC1A_MOUSE", "id": "P43081-1", "name": "Guanylyl cyclase-activating protein 1", "aln": "MGNIMEGKSVEELSSTECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSPSASQYVEQMFETFDFNKDGYIDFMEYVAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRAIRTINPWSDSSMSAEEFTDTVFAKIDINGDGELSLEEFMEGVQKDQMLLDTLTRSLDLTGIVRRLQNGEHEEAGTGDLAAEAAG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43080-1", "uniprot_id": "GUC1A_HUMAN", "id": "P43080-1", "name": "Guanylyl cyclase-activating protein 1", "aln": "MGNVMEGKSVEELSSTECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSPSASQYVEQMFETFDFNKDGYIDFMEYVAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIQAIRAINPCSDTTMTAEEFTDTVFSKIDVNGDGELSLEEFIEGVQKDQMLLDTLTRSLDLTRIVRRLQNGEQDEEGA-DEAAEAAG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UZP3-1", "uniprot_id": "A0A8N7UZP3_DANRE", "id": "A0A8N7UZP3-1", "name": "", "aln": "MGNST-GSTVDDLQAVEMHLWYKKFMTECPSGQLTLHEFKQFFGLRGLDPEANAYIEQMFRTFDMNKDGYIDFMEYVAALSLVMRGKMEHKLRWYFRLYDVDGNGCIDRYELLNIIKAIRAINGSETQESSAEEFTNRVFERIDINGDGELSLDEFVAGARSDEEFMEVMMKSLDLTHIVAMIHNRRHSV------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *.:*::*.:.* * ****************:**:*****:.*.*.*. *:****.***:******************::**:*:******:************ ***.**:***:** . :*****: ** :**:********:**: *.:.*: :::.: :***** ** ::* .:. ", "identical_positions": 120, "similar_positions": 47, "identity": "59.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011128-8", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51842-1", "uniprot_id": "GUC2F_RAT", "id": "P51842-1", "name": "Retinal guanylyl cyclase 2", "aln": "----MFLGPWPFSRLLSWFAIS--SRLSGQHGLTSSKFLRYLCLLA---LLPLIWWGQALPYKIGVIGPWTCDPFFSKALPEVAAALAIERISRDMSFDRSYSFEYVILNEDCQTSKALTSFISHQQMASGFVGPANPG--------------YCEAASLLGNSWDKGIFSWACVNHELDNKHS---------------------------YPTFSRTLPSPIRVLVTVMKYFQWAHAGVISSDEDIWVHTANQVSSALRSHG------------------LPVGVVLTSGQD------------------------------------SRSIQKALQQIRQADRIRIIIMCMHSALIGGETQTHFLELAHDLKMTDGTYVFVPY----DVLLYSLPYKHSPYQVLRNNQKLREAYDAVLTITVES-HEKTFYEAFTEAAAGGEIPEKLDSHQVSPLFGTIYNSIYFIAQAMSNALKENGQASAASLTRHSRNMQFYGFN------------------------------------------------------------QLIRTDSNGNGISEYVILDTNGKE----WELRGTYTVDMETELLR----FRGTPIHFPGGRPTSADAKCWFAQGKICQGGIDP-ALAMMVCFALLLALLSINGFAYFIRRRINKIQLIKGPNRILLTLEDVTFIN-----------------------------------PHFGSKRGSRASVSFQIISEVQSGRSPR---LSFSSGSLTPATYENSNIAIYQGDWVWLKKFPPGDFGDIKSIKSSASDVFEMMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRRSLEDILTQDDVKLDWMFKSSLLLDLIKGMKYLHHR-EFIHGRLKSRNCVVDGRFVLKVTDYGFNNILEMLRLSEEEPSEEELLWTAPELLR---------APGGIRLGSFAGDVYSFAIIMQEVMVRGAPFCMMDLSAKEVIDRLKMPPPVYRPVVSPEFAPPECLQLMKQCWAEAAEQRPTFDEIFNQFKTFNKGKKTNIIDSMLRMLEQYSSNLEDLIRERTEELEIEKQKTEKLLTQMLPPSVAESLKKGCTVEPEGFDLVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPKRNGSRHAAEIANMSLDILSSVGTFKMRHMPEVPVRIRIGLHTGPVVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVSLSTVTILRTLSEGYEVELRGRTELKGKGTEETFWLVGKKGFTKPLPVPPPVGKDGQVGHGLQPAEIAAFQRRKAERQLVRNKP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SDA5-1", "uniprot_id": "GUC2F_MOUSE", "id": "Q5SDA5-1", "name": "Retinal guanylyl cyclase 2", "aln": "----MFLGPWPFSRLLSWFAIS--SRLSGQHGLPSSKFLRCLCLLA---LLPLLRWGQALPYKIGVIGPWTCDPFFSKALPEVAAALAIERISRDKTFDRSYSFEYVILNEDCQTSKALASFISHQQMASGFVGPANPG--------------FCEAASLLGTSWDKGIFSWACVNHELDNKHS---------------------------FPTFSRTLPSPIRVLVTVMKYFQWAHAGVISSDEDIWMHTANRVSSALRSQG------------------LPVGVVLTSGRD------------------------------------SQSIQKALQQIRQADRIRIIIMCMHSALIGGETQTHFLELAHDLKMTDGTYVFVPY----DVLLYSLPYKHSPYQVLRNNPKLREAYDAVLTITVES-HEKTFYEAYAEAAARGEIPEKPDSNQVSPLFGTIYNSIYFIAQAMNNAMKKNGRASAASLVQHSRNMQFYGFN------------------------------------------------------------QLIKTDSNGNGISEYVILDTNGKE----WELRGTYTVDMETELLR----FRGTPIHFPGGRPTSADAKCWFAERKICQGGIDP-ALAMMVCFALLIALLSINGFAYFIRRRINKIQLIKGPNRILLTLEDVTFIN-----------------------------------PHFGSKRGSRASVSFQIISEVQSGRSPR---LSFSSGSLTPATYENSNIAIYEGDWVWLKKFPPGDFGDIKSIKSSASDVFEMMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRRSLEDILTNDDVKLDWMFKSSLLLDLIKGMKYLHHR-EFIHGRLKSRNCVVDGRFVLKVTDYGFNDILEMLRLSEEEPSEEELLWTAPELLR---------APGGIRLGSFAGDVYSFAIIMQEVMVRGAPFCMMDLPAKEIIDRLKMPPPVYRPVVSPEYAPAECLQLMKQCWAEASEQRPTFDEIFNQFKTFNKGKKTNIIDSMLRMLEQYSSNLEDLIRERTEELEIEKQKTEKLLTQMLPLSVAESLKKGCTVEPEGFDLVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPKRNGSRHAAEIANMSLDILSSVGTFKMRHMPEVPVRIRIGLHSGPVVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVSLSTVTILQTLSEGYEVELRGRTELKGKGTEETFWLVGKKGFTKPLPVPPPVGKDGQVGHGLQPAEIAAFQRRKAERQLVRNKP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51841-1", "uniprot_id": "GUC2F_HUMAN", "id": "P51841-1", "name": "Retinal guanylyl cyclase 2", "aln": "----MFLGLGRFSRLVLWFAAF--RKLLGHHGLASAKFLWCLCLLS---VMSLPQQVWTLPYKIGVVGPWACDSLFSKALPEVAARLAIERINRDPSFDLSYSFEYVILNEDCQTSRALSSFISHHQMASGFIGPTNPG--------------YCEAASLLGNSWDKGIFSWACVNYELDNKIS---------------------------YPTFSRTLPSPIRVLVTVMKYFQWAHAGVISSDEDIWVHTANRVASALRSHG------------------LPVGVVLTTGQD------------------------------------SQSMRKALQRIHQADRIRIIIMCMHSALIGGETQMHLLECAHDLKMTDGTYVFVPY----DALLYSLPYKHTPYRVLRNNPKLREAYDAVLTITVES-QEKTFYQAFTEAAARGEIPEKLEFDQVSPLFGTIYNSIYFIAQAMNNAMKENGQAGAASLVQHSRNMQFHGFN------------------------------------------------------------QLMRTDSNGNGISEYVILDTNLKE----WELHSTYTVDMEMELLR----FGGTPIHFPGGRPPRADAKCWFAEGKICHGGIDP-AFAMMVCLTLLIALLSINGFAYFIRRRINKIQLIKGPNRILLTLEDVTFIN-----------------------------------PHFGSKRGSRASVSFQITSEVQSGRSPR---LSFSSGSLTPATYENSNIAIYEGDWVWLKKFSLGDFGDLKSIKSRASDVFEMMKDLRHENINPLLGFFYDSGMFAIVTEFCSRGSLEDILTNQDVKLDWMFKSSLLLDLIKGMKYLHHR-EFVHGRLKSRNCVVDGRFVLKVTDYGFNDILEMLRLSEEESSMEELLWTAPELLR---------APRGSRLGSFAGDVYSFAIIMQEVMVRGTPFCMMDLPAQEIINRLKKPPPVYRPVVPPEHAPPECLQLMKQCWAEAAEQRPTFDEIFNQFKTFNKGKKTNIIDSMLRMLEQYSSNLEDLIRERTEELEIEKQKTEKLLTQMLPPSVAESLKKGCTVEPEGFDLVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPKRNGSRHAAEIANMSLDILSSVGTFKMRHMPEVPVRIRIGLHSGPVVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVSLSTVTILQNLSEGYEVELRGRTELKGKGTEETFWLIGKKGFMKPLPVPPPVDKDGQVGHGLQPVEIAAFQRRKAERQLVRNKP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F111-1", "uniprot_id": "E7F111_DANRE", "id": "E7F111-1", "name": "Guanylate cyclase", "aln": "----MPHPSNAFHSFLPARGTSGLRSPSQMPHFSSDPKHIYLCLLWSTIILCLLPATNAATIKVGVVGPWSCDPIFTKAQPGVAARLAVAHINKDPYLSQGITFDYIILDEDCETSKSFARFLGYYTRASGFIGPVNPG--------------YCEAASLLGKSWNKAVFSWSCIEHELDDVRS---------------------------HPTFARTMPVPSLVLLSFMRHFRWAHVGIISSSEDVWVEAAIKLANALRSHG------------------LPVGIVTSARND------------------------------------HTSVRQTLAKVRKVADLRLVILVMHSVLIGGRTQKLLLETAHDMRMTDGSLVFMSY----DTLFYSLPYHHVTQPALRYNSKLLRAYDAVLTITIESPKEQSFYQAFEKAQEDGELPKHLKPQQVSPLFGTIYSSIVFMAHAVQSVRAAGQWMSGGNIAQNARNLLFKGGS------------------------------------------------------------SLQANSSD-FGMLDYVILDTDGFS----WELQPTYRIEMQTDMVR----FLGRHIHFPYAGPPRTDSSCWFTHGIICRGGVNLFHMISMFLLGFLFIFLSIG-CSYCIRRKINKIRLVRGPNKILLTLNDVTFIN-----------------------------------PSLSNKK---LSVDDSKASDTRMSISERS--LVSPMSSQSPATYENSNVAIYEGDWAWMKRLP---YGTFRSITPNTSDVFELMKDLRHENINPFLGFFHDCGVFAIVTEFCSRGSLEDLLVNDDVKLDWMFKSSLILDLIKGMKYLHHR-NVCHGRLKSRNCVVDGRFVLKITDYGYNEVLESQRFPYIEPPAEDLLWTAPEILR---------GSYPGLHGTHSGDVYSFSIIMQEVVMRGPPFCMLENTFDEIVQKVRKPPPMCRPIVSPDHAPMECIQLMKQCWNEQPEKRPTFDEIFDQFKNVNKGKKTNIIDSMLRMLEQYSSNLEELIRERTEELEIEKQKTEKLLTQMLPPSVAEALKLGTTVEPEHFESVSLYFSDIVGFTTISANSEPIEVVDLLNDLYTTFDAVIGNHDVYKVETIGDAYMVASGVPVPNGNRHAAEIANMALDILSAVGTFRMRHMPDVPVRIRIGLHTGPCVAGVVGLTMPRYCLFGDTVTTASRMESTGLPYRIHVHSSTVKILMELKLGYRVELRARTELKGKRIEETYWLTGRDGFTKPLPVPP-VLKSGQMAHGLQMEEIAAYKKRKAEAQLAKKKN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A4D6K026-1", "uniprot_id": "A0A4D6K026_DROME", "id": "A0A4D6K026-1", "name": "Guanylate cyclase", "aln": "MKLTTCQIAKVFPLLTAFFFLNSPSAASLSFGLSPTFASASASSSLSSSSSSSSHFHSEKPLHSDVLVLRAAKPSRAIATSADAATRSVPASAAETTLGSKSIWPTAIQTKSPRNAREAGRHKRQMQKPAIQQQPLQQQQQRINPPQQKRQQQQQQQQQVQHQAQRVGVLIPPSLHVDLTHVQQGFQNFLDFFQLHLFNVTVDFLRDVDLSGFIKLLELPKYTSVIKTLNAGIMVASHVDVDQNSTIYIGTPSQPRQQHRLHSKQEQEPHRHHHEDSKAKQFPAGEEESHSSGETEENHWNDARIFSGHCHQLAEQLALDFNKTVVLWPCPRMKISSNFLPSFEAISLAVQSISTKLNWSQVDIYIGDDNWGLGLAIAANLHVPYRIEIGRTIRDLHSQDKPGKAIIITAPLNDASTILLLSTIELDWTEQARKDGQGSRPGRQHTKILLIDMAASSLDTQHGFYKYLSRMGGSQSDAFARNTGSPAEVVSSNLLVLTLLNDRHRLFLNAAGLMATMQNFRAPLNGNYKDPPPSGHRNASLHKLYPYRNLLPLYDTIVTTTTQSDTSETSPQFDFVVLDIVRDAPVATYKWRPLLILESDPGSRGGGSVVEGGGSYISHSIHPGYDEWLLVSSVLLWQCGAICWTIAAICVCLLVIMIAGIVAGGIAMRNYFLRKRLSKGPNKIVLSASDFVFPVDSRRVDEGIEAMLCCWLQQLQEFGGPEVDKPDLLKGSIGSLKNLGFVIPGAAAPGSAGAITTTANGKSGSSATGSLARHNPAHLDMRARYNGDLVQLKEVNINGSAELRTKAMDLLVMAHGLRHENINPLIGWLSDPNRTAMVFDYCSRGSLQDVLIMDEIKLDWSFRLSLLTDLVRGMRYLHTSPLRVHGALTSRNCVVDARWVLKITDYGLNSFYESQGLPPRTRSAKELLWTAPELLRNMKLHQHHHQHGRIQLGTQLGDVYSFGIIMQEVVVRGEPYCMLSLSPEEIIVKIKKPPPLIRPSVSKGAAPPEAINIMRQCWAEQPDMRPDFNSVYERFKMLNHGRKVNFVDTMFQMLEKYSNNLEELIRERTEQLDIERKKTEQLLNRMLPSSVAEKLKMGLAVDPEEFSDVTIYFSDIVGFTTIAAHCSPVQVVDLLNDLYTIFDATINAYNVYKVETIGDAYMVVSGLPVKIP-DHAEQIATMALDLLHQSGRFNVKHLPGVPLQLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGSSWRIHMSQETRDRLDAR-GGYAIEPRGLIDIKGKGMMNTFWLLGKKGFDKPLPAPPPIGESHGLDESLIRNSITLKAQANKSRTSTNPSSSQSSSLAGESVEVKVEITPPTNADLASGTNLPNSYSLDSNSTNTISPNATLCPEFPGKTTPSSTSPQSRKLSELTPENLLNPNSFNRLPSSTGGSSSRLYKKIEEMMDLSSPYNHYKCLSPSESNLTQFYDGKYLYGSVAGGAGGGQAGGGACASIALSGSGCGGGASRFDSKPGSSRLLRRQFSLDRDDQQAKGEQQHHQHSLQANTYSGLVGGCGGGVKSSMLDIPLLHDTTRSPKGTLTRSHKQNSASITQDLEKIEEIPLSPASSQHHSSLDSNLNRSPPSTLEAQSPPLPPMSPPQLSAPTSPAPSRTLNGIYAHNSNSTSSHGAANNNNGTHPGPELTLNAEQLLSRXGTI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : :.. . . : .*: :... : * . ** :: : :. : * :. ..:: . .: * : : .: : .:: ..:. :* . . :* *: :. : * :.... ::: :. : . * :. :*.* : . :: : : . : : : : : * ...: : : .: :: .: :.:.* . : .* :. . .: . * * :* *:* : : : : .: . .:. :.* :. :::: . .. : *: . *: ::*:** :: : :: : . * ::. . . * .: : : * : : ::: : .* . :*. : : :* :***:*:*: .*..* :.. : : . . : . .: : * :: ::: : : :: . .: . : *:: : :.*****:**::*:: * . *:* ::*** **:*:* :::**** *: **: **::**:*** ** *.*******.*:***:**** *.. * :. . ::*******:** *: ******.******::** *:**:. . .*:: ::: ***: ** *. ** *.:::*:*** * .: ** *:.::::** .*:*:*.*::*:*::***:**.***:*******:*:**::***:**.:*** **** ** * :*:** *. *::***********:* ..*::********** *** *. ::*************.**:* ** :**.*:**:* * *.::*:* **:::*****:** ******************.********* .:***: .* * ** :* *. ::*** :*:** *:.** ****.** : :. : ..* .*: : : . .. . ", "identical_positions": 303, "similar_positions": 334, "identity": "17.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011128-9", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51840-1", "uniprot_id": "GUC2E_RAT", "id": "P51840-1", "name": "Retinal guanylyl cyclase 1", "aln": "--------------------MSAWLLPAGG-----FPGAGFCIPAWQSRSSLSRVLRWPGPGLPGLLLLLLLPSPS---AFSAVFKVGVLGPWACDPIFARARPDLAARLATDRLNRDLALDGGPWFEVTLLPEPCLTPGS---------------------------------------------------------------------------------------------LGAVSSALTRVSGLVGPVN------------------------------------------------------PAACRPAELLAQEAGVALVPWGCPGTRAAGTTAP----AVTPAADALYVLLKAFRWARVALITAPQDLWVEAGRALSTALRARGLPVALVTSMVPSDLSGAREALRRIRDGPRVRVVIMVMHSVLLG-----------GEEQRYLLEAAEELGLTDGSLVFLPFDT----------LHYALSPGPEALAAFVNSSKLRRAHDAVLTLTRRCPPGGSVQDSLRRAQEHQELPLDLDLKQVS----PLFGTIYDAVFLLAGGVTRARAAVGGGWVSGASVARQMREAQVFGF-----CGILGRTEEPSFVLLDTDAAGERLFTTHLLDP-----VLGSLRSAGTPVHFPRGAPAPGPDPSCWFDPDVICNGGVEPGLVFVGFLLVIVVGLTGAFLAHYLRHR--------------------LLHMQMVSG-----PNKIILTLEDVTFLHPQGG----SSRKVAQGSRSSLATRSTSDIRSVPSQPQESTNIGLYEGDWVWLKKFP-GEHHMAIRPATKMAFSKLRELRHENVALYLGLFLAGTADSPATPGEGILAVVSEHCARGSLHDLLAQRDIKLDWMFKSSLLLDLIKGMRYLHHR-GVAHGRLKSRNCVVDGRFVLKVTDHGHGRLLEAQRVLPEPPSAEDQLWTAPELLRDPALERR---------GTLAGDVFSLGIIMQEVVCRSTPYAMLELTPEEVIQRVRSPPPLCRPLVSMDQAPMECIQLMAQCWAEHPELRPSMDLTFDLFKGINKGRKTNIIDSMLRMLEQYSSNLEDLIRERTEELEQEKQKTDRLLTQMLPPSVAEALKMGTSVEPEYFEEVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPQRNGQRHAAEIANMSLDILSAVGSFRMRHMPEVPVRIRIGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNMSTVRILRALDQGFQMECRGRTELKGKGVEDTYWLVGRVGFNKPIPKPP------DLQPGASNHGISLQEIPPERRKKLEKARPGQFTGK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52785-1", "uniprot_id": "GUC2E_MOUSE", "id": "P52785-1", "name": "Retinal guanylyl cyclase 1", "aln": "--------------------MSAWLLPAGG-----LPGAGFCVPARQSPSSFSRVLRWPRPGLPGLLLLLLLPSPS---ALSAVFKVGVLGPWACDPIFARARPDLAARLAANRLNRDFALDGGPRFEVALLPEPCLTPGS---------------------------------------------------------------------------------------------LGAVSSALSRVSGLVGPVN------------------------------------------------------PAACRPAELLAQEAGVALVPWGCPGTRAAGTTAP----AVTPAADALYVLLRAFRWARVALITAPQDLWVEAGRALSTALRARGLPVALVTSMETSDRSGAREALGRIRDGPRVRVVIMVMHSVLLG-----------GEEQRYLLEAAEELALTDGSLVFLPFDT----------LHYALSPGPEALAAFVNSSQLRRAHDAVLTLTRRCPPGGSVQDSLRRAQEHQELPLDLNLKQVS----PLFGTIYDAVFLLAGGVKRARTAVGGGWVSGASVARQVREAQVSGF-----CGVLGRTEEPSFVLLDTDASGEQLFATHLLDP-----VLGSLRSAGTPMHFPRGGPAPGPDPSCWFDPDVICNGGVEPGLVFVGFLLVIGMGLTGAFLAHYLRHR--------------------LLHMQMASG-----PNKIILTLEDVTFLHPPGG----SSRKVVQGSRSSLATRSASDIRSVPSQPQESTNVGLYEGDWVWLKKFP-GEHHMAIRPATKTAFSKLRELRHENVALYLGLFLAGTADSPATPGEGILAVVSEHCARGSLHDLLAQREIKLDWMFKSSLLLDLIKGMRYLHHR-GVAHGRLKSRNCVVDGRFVLKVTDHGHGRLLEAQRVLPEPPSAEDQLWTAPELLRDPSLERR---------GTLAGDVFSLAIIMQEVVCRSTPYAMLELTPEEVIQRVRSPPPLCRPLVSMDQAPMECIQLMTQCWAEHPELRPSMDLTFDLFKSINKGRKTNIIDSMLRMLEQYSSNLEDLIRERTEELEQEKQKTDRLLTQMLPPSVAEALKMGTSVEPEYFEEVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGAHDVYKVETIGDAYMVASGLPQRNGQRHAAEIANMSLDILSAVGSFRMRHMPEVPVRIRIGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNMSTVRILRALDQGFQMECRGRTELKGKGIEDTYWLVGRLGFNKPIPKPP------DLQPGASNHGISLQEIPPERRKKLEKARPGQFTGK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02846-1", "uniprot_id": "GUC2D_HUMAN", "id": "Q02846-1", "name": "Retinal guanylyl cyclase 1", "aln": "--------------------MTACARRAGG-----LPDPGLCGPAWWAP-SLPRLPR-ALPRLP-LLLLLLLLQPP---ALSAVFTVGVLGPWACDPIFSRARPDLAARLAAARLNRDPGLAGGPRFEVALLPEPCRTPGS---------------------------------------------------------------------------------------------LGAVSSALARVSGLVGPVN------------------------------------------------------PAACRPAELLAEEAGIALVPWGCPWTQAEGTTAP----AVTPAADALYALLRAFGWARVALVTAPQDLWVEAGRSLSTALRARGLPVASVTSMEPLDLSGAREALRKVRDGPRVTAVIMVMHSVLLG-----------GEEQRYLLEAAEELGLTDGSLVFLPFDT----------IHYALSPGPEALAALANSSQLRRAHDAVLTLTRHCPSEGSVLDSLRRAQERRELPSDLNLQQVS----PLFGTIYDAVFLLARGVAEARAAAGGRWVSGAAVARHIRDAQVPGF-----CGDLGGDEEPPFVLLDTDAAGDRLFATYMLDP-----ARGSFLSAGTRMHFPRGGSAPGPDPSCWFDPNNICGGGLEPGLVFLGFLLVVGMGLAGAFLAHYVRHR--------------------LLHMQMVSG-----PNKIILTVDDITFLHPHGG----TSRKVAQGSRSSLGARSMSDIRSGPSQHLDSPNIGVYEGDRVWLKKFP-GDQHIAIRPATKTAFSKLQELRHENVALYLGLFLARGAEGPAALWEGNLAVVSEHCTRGSLQDLLAQREIKLDWMFKSSLLLDLIKGIRYLHHR-GVAHGRLKSRNCIVDGRFVLKITDHGHGRLLEAQKVLPEPPRAEDQLWTAPELLRDPALERR---------GTLAGDVFSLAIIMQEVVCRSAPYAMLELTPEEVVQRVRSPPPLCRPLVSMDQAPVECILLMKQCWAEQPELRPSMDHTFDLFKNINKGRKTNIIDSMLRMLEQYSSNLEDLIRERTEELELEKQKTDRLLTQMLPPSVAEALKTGTPVEPEYFEQVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPQRNGQRHAAEIANMSLDILSAVGTFRMRHMPEVPVRIRIGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNLSTVGILRALDSGYQVELRGRTELKGKGAEDTFWLVGRRGFNKPIPKPP------DLQPGSSNHGISLQEIPPERRRKLEKARPGQFS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BCH5-1", "uniprot_id": "A0A8M2BCH5_DANRE", "id": "A0A8M2BCH5-1", "name": "Guanylate cyclase", "aln": "--------MNDHTSFLCQSHHPRWQTQSSAGKRRRKQSSSQKSETPASPVSSSPVLRSHSWWGNCFLLPLVMLSYFPCEAWGTTFKIAIVGPWACDPMYSKALPDLAARLAMSRINKDPELNKGYWYDYTVINEDCSSSRG---------------------------------------------------------------------------------------------LARFAELEGYGSAFLGPAN------------------------------------------------------PGYCTAATLLAKNWNKGILSWGCLKAEMDEEMYPTFLRPLPLSSRVLFSVLRFFRWAHVGIVTAEGDMWEATGHELAASLRALGLPVGKVVTMEQ-DKEGPRQALQAIRDTDRVRVVIMCMHSALIG-----------GEEQYQLLTTALEMRMIDRGYIFIPYDT----------LLYSLPYENVKYPILANDSKLRRAYDGVLTVTMDQ-GEQNFYEAFNAAQESFEIRGSTSAEEVTRWVSPFFGTIYNMIYYTAMAAEQSRASSGGRWVSGDLLSQNEGGFEFDGFNQRISGGTNGEGMQVRYAVLDSDGSGSSLYRTHALEASHTYGKYGGLKYLGKSIHFA--GASPSSDANCWFSPYIACSGGLDGVTLFFLLMFFIVLIAGAGILFLQVRKYGAGG----------------FFGAFIGGGG---SPTKIVLTLDDLVFINTTLSRRKLNDESMLKSQLDVKTPRHSVSGRSYITSTPETSNVAVFEGDWVWLKKCPCADSITEISESTQTIFVKLRDMRHENLNLFLGLFMD----------TGIFGIVTEHCTRGSLEDLLNNEEMRLDWMFKSSLLLDLIRGMKYLHNR-GIIHGRLKSRNCVVDGRFVLKVTDYGFNEILNCQNIILEDNAPEDQFWTAPEILRNPDLKKK---------GTYPGDVYSFSIIMQEVISRCAPFCMLDMPPEEIIEKVRSPPPLCRPTVSMDEAPLDVIQLMKQAWSEEPEQRPTFEDIFRQFKSMNKGKKTNIIDSMLRMLEQYSSNLEDLIRERTEELEVERQKTDALLAQMLPKSVALALKTGKPVKPEHFAEVTLYFSDIVGFTTISALSEPIEVVDLLNDLYTHFDGIIAIHDVYKVETIGDAYMVASGVPNRNGTRHAAEMANMSLDILHCIGTFKMRHMPDVKVKIRIGLHSGPVVAGVVGLKMPRYCLFGDTVNTASRMESTGLPYRIHVNQSTVDVLNSLKLGYKIDTRGRTELKGKGVEETFWLVGRDGFDKPLPIPP------DLTPGASNHGISLDEIPTDRRQKFLDRQKRMGN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A4D6K026-1", "uniprot_id": "A0A4D6K026_DROME", "id": "A0A4D6K026-1", "name": "Guanylate cyclase", "aln": "MKLTTCQIAKVFPLLTAFFFLNSPSAASLSFGLSPTFASASASSSLSSSSSSSSHFHSEKPLHSDVLVLRAAKPSRAIATSADAATRSVPASAAETTLGSKSIWPTAIQTKSPRNAREAGRHKRQMQKPAIQQQPLQQQQQRINPPQQKRQQQQQQQQQVQHQAQRVGVLIPPSLHVDLTHVQQGFQNFLDFFQLHLFNVTVDFLRDVDLSGFIKLLELPKYTSVIKTLNAGIMVASHVDVDQNSTIYIGTPSQPRQQHRLHSKQEQEPHRHHHEDSKAKQFPAGEEESHSSGETEENHWNDARIFSGHCHQLAEQLALDFNKTVVLWPCPRMKISSNFLP----SFEAISLAVQSISTKLNWSQVDIYIGDDNWGLGLAIAANLHVPYRIEIGRTIRDLHSQDKPGKAIIITAPLNDASTILLLSTIELDWTEQARKDGQGSRPGRQHTKILLIDMAASSLDTQHGFYKYLSRMGGSQSDAFARNTGSPAEVVSSNLLVLTLLNDRHRLFLNAAGLMATMQNFRAPLNGNYKDPPPSGHRNASLHKLYPYRNLLPLYDTIVTTTTQSDTSETSPQFDFVVLDIVRDAPVATYKWRP-------LLILESDPGSRGGGSVVEGGGSYISHSIHP-----GYDEWLLVSSVLLWQCGAICWTIAAICVCLLVIMIAGIVAGGIAMRNYFLRKRLSKGPNKIVLSASDFVFPVDSRRVDEGIEAMLCCWLQQLQEFGGPEVDKPDLLKGSIGSLKNLGFVIPGAAAPGSAGAITTTANGKSGSSATGSLARHNPAHLDMRARYNGDLVQLKEVN-INGSAELRTKAMDLLVMAHGLRHENINPLIGWLSD----------PNRTAMVFDYCSRGSLQDVLIMDEIKLDWSFRLSLLTDLVRGMRYLHTSPLRVHGALTSRNCVVDARWVLKITDYGLNSFYESQGLPPRTRSAKELLWTAPELLRNMKLHQHHHQHGRIQLGTQLGDVYSFGIIMQEVVVRGEPYCMLSLSPEEIIVKIKKPPPLIRPSVSKGAAPPEAINIMRQCWAEQPDMRPDFNSVYERFKMLNHGRKVNFVDTMFQMLEKYSNNLEELIRERTEQLDIERKKTEQLLNRMLPSSVAEKLKMGLAVDPEEFSDVTIYFSDIVGFTTIAAHCSPVQVVDLLNDLYTIFDATINAYNVYKVETIGDAYMVVSGLPVKIP-DHAEQIATMALDLLHQSGRFNVKHLPGVPLQLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGSSWRIHMSQETRDRLDARG-GYAIEPRGLIDIKGKGMMNTFWLLGKKGFDKPLPAPPPIGESHGLDESLIRNSITLKAQANKSRTSTNPSSSQSSSLAGESVEVKVEITPPTNADLASGTNLPNSYSLDSNSTNTISPNATLCPEFPGKTTPSSTSPQSRKLSELTPENLLNPNSFNRLPSSTGGSSSRLYKKIEEMMDLSSPYNHYKCLSPSESNLTQFYDGKYLYGSVAGGAGGGQAGGGACASIALSGSGCGGGASRFDSKPGSSRLLRRQFSLDRDDQQAKGEQQHHQHSLQANTYSGLVGGCGGGVKSSMLDIPLLHDTTRSPKGTLTRSHKQNSASITQDLEKIEEIPLSPASSQHHSSLDSNLNRSPPSTLEAQSPPLPPMSPPQLSAPTSPAPSRTLNGIYAHNSNSTSSHGAANNNNGTHPGPELTLNAEQLLSRXGTI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .. : : * . : .*: : . . . .: .. * .: ::: * : * :: . :: : :. . : :*. . * ** : . :: * * . * .. : .: : : *::* : . : . : : : * * : : . :: :. *.:: :* * * : : : . . : : *. : .*. : .. .:. : . . . : .:*: : : :.:: :* : : .: * : :: :.. . .. : : . . . * * : : :: : : . : .* * : :: .: : . . . . . ::** * **: : : : : : :****: :* : . .:* ::*:****.*:* :::*** *: *** **::*::*** ** *.****:**.*:***:**:* . : :.* : . .:: :*****:**: *.:: ** ***:*:.******: * *:.**.:.***:: :::.**** ** ** . ** : * :* *.*:*.*: ** :: : ** :*:*:*.*::*:*::***:**.***:*******:*: *::**: ** :*** *** ** * .*.** * :**:***********:* ..*::********** **. * ::*************.**:* : ** ::*.*:**:* * *.::*:* * :::*****:** ******.********************* .:***:. .* * : *: :: ** ::**** :*:**:*: **:**:* ** .* . .:.*:*. . . * . . ", "identical_positions": 281, "similar_positions": 288, "identity": "16.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011205-10", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05508-1", "uniprot_id": "NU4M_RAT", "id": "P05508-1", "name": "NADH-ubiquinone oxidoreductase chain 4", "aln": "MLKIIFPSIMLLPLTWLSANKKIWTNVTSYSFLVSLLSLSLLWQNDENYLNFS-VMFSSDPLSTPLIILTTWLLPLMMLASQNHMKKENMMHQKLYISMLISLQILLIMTFSATELILFYILFEATLIPTLIIITRWGNQTERLNAGIYFLFYTLIGSIPLLIALISIQNSMGTLNFLILSLTTHPLPSTWSNTILWLACMMAFMIKMPLYGVHLWLPKAHVEAPIAGSMILAAILLKLGGYGMMRVSIILDPLTKSLAYPFIILSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVITAIMIQTPWSFMGATMLMIAHGLTSSLLFCLANTNYERIHSRTMIMARGLQMIFPLMATWWLLASLANLALPPLINLMGELFIVMATFSWSNPSIILMATNIVITGIYSMYMIITTQRGKLTSHMNNLQPSHTRELTLMALHIIPLMLLTINPKLITGLTM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P03911-1", "uniprot_id": "NU4M_MOUSE", "id": "P03911-1", "name": "NADH-ubiquinone oxidoreductase chain 4", "aln": "MLKIILPSLMLLPLTWLSSPKKTWTNVTSYSFLISLTSLTLLWQTDENYKNFS-NMFSSDPLSTPLIILTAWLLPLMLMASQNHLKKDNNVLQKLYISMLISLQILLIMTFSATELIMFYILFEATLIPTLIIITRWGNQTERLNAGIYFLFYTLIGSIPLLIALILIQNHVGTLNLMILSFTTHTLDASWSNNLLWLACMMAFLIKMPLYGVHLWLPKAHVEAPIAGSMILAAILLKLGSYGMIRISIILDPLTKYMAYPFILLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIASIMIQTPWSFMGATMLMIAHGLTSSLLFCLANSNYERIHSRTMIMARGLQMVFPLMATWWLMASLANLALPPSINLMGELFITMSLFSWSNFTIILMGINIIITGMYSMYMIITTQRGKLTNHMINLQPSHTRELTLMALHMIPLILLTTSPKLITGLTM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P03905-1", "uniprot_id": "NU4M_HUMAN", "id": "P03905-1", "name": "NADH-ubiquinone oxidoreductase chain 4", "aln": "MLKLIVPTIMLLPLTWLSKKHMIWINTTTHSLIISIIPLLFFNQINNNLFSCS-PTFSSDPLTTPLLMLTTWLLPLTIMASQRHLSSEPLSRKKLYLSMLISLQISLIMTFTATELIMFYIFFETTLIPTLAIITRWGNQPERLNAGTYFLFYTLVGSLPLLIALIYTHNTLGSLNILLLTLTAQELSNSWANNLMWLAYTMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLAAVLLKLGGYGMMRLTLILNPLTKHMAYPFLVLSLWGMIMTSSICLRQTDLKSLIAYSSISHMALVVTAILIQTPWSFTGAVILMIAHGLTSSLLFCLANSNYERTHSRIMILSQGLQTLLPLMAFWWLLASLANLALPPTINLLGELSVLVTTFSWSNITLLLTGLNMLVTALYSLYMFTTTQWGSLTHHINNMKPSFTRENTLMFMHLSPILLLSLNPDIITGFSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9MIY1-1", "uniprot_id": "NU4M_DANRE", "id": "Q9MIY1-1", "name": "NADH-ubiquinone oxidoreductase chain 4", "aln": "MLKVLIPTIMLFPTIWLSSSKWLWTTTTMNSFLIAFISLTWLKWTSDTGWNASNSYMAADPLSTPLLVLTCWLLPLMILASQNHINSEPVNRQRMYITLLASLQTFMIMAFGATKIIMFYIMFEATLIPTLIIITRWGNQAERLNAGTYFLFYTLAGSLPLLVALLLLQQSTGTLSMLVLQYSDPLLLNSWGHKIWWAGCLIAFLVKMPLYGMHLWLPKAHVEAPVAGSMILAAVLLKLGGYGMMRMMVMLDPLSKQLAYPFIILALWGVIMTGLVCLRQTDLKSLIAYSSVGHMGLVAGGILIQTPWGFTGAIILMIAHGLTSSALFCLANTSYERTHSRTMILARGLQMVLPLATVWWFIANLANLALPPLPNLMGELMIITALFNWSPWTIIITGMGTLITANYSLYMFLTSQRGSIPEHITNLSPSHTREHLLMTLHLIPIILLMLKPELMWGWCN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18931-1", "uniprot_id": "NU4M_DROME", "id": "P18931-1", "name": "NADH-ubiquinone oxidoreductase chain 4", "aln": "MLKIIFFLLFLIPFCFINN---MYWMVQIMMFFISFIFLLMNNFMN--YWSEISYFLGCDMLSYGLILLSLWICSLMLLASE--MINKHNNYKNLFLLNIIILLLLLILTFSSMSLFMFYLFFESSLIPTLFLILGWGYQPERLQAGLYLLFYTLLVSLPMLIGIFYLMNKIGSMNFYLMNN------FMFNYDLLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGMLRVISFLQLMNLKYSFVWISISLVGGVLVSLVCLRQTDLKALIAYSSVAHMGIVLSGLLTMTYWGLCGSYTLMIAHGLCSSGLFCLANVSYERLGSRSMLINKGLLNFMPSMTLWWFLLSSANMAAPPTLNLLGEIYLLNSIVSWSWISMILLSFLSFFSAAYTLYLYSFSQHGKLFSGVYSFSSGKIREYLLMLLHWLPLNLLILKSESFMLWL-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***::. ::*:* ::. : . ::::: * . . :..* *: *::*: *: .* ::**: : .. :.::: : * :*::* : .:::**::**::***** :* ** *.***:** *:***** *:*:*:.:: : *::.: :: : : : **::***:: :************::***:**.::****.***:*: :*: :. :: :: ::* * ::.. :********:******:.**.:* .:: * *.: *: ******* ** ****** .*** ** *:: :** .:* : **:: . **:* ** **:**: : : ..** :::: . ..:. *::*: :* *.: : .:... ** ** :* *: ** ... : ", "identical_positions": 147, "similar_positions": 155, "identity": "31.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011205-12", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P11661-1", "uniprot_id": "NU5M_RAT", "id": "P11661-1", "name": "NADH-ubiquinone oxidoreductase chain 5", "aln": "MN--MMTSSILMILILLTTPIIISMTNLPKLIDFPSYATSSIKFSFLLSLLPLLLFFHHNTEYMITNWHWLTINSIKLTMSFKIDYFSILFLSVALFVTWSIMQFSSWYMHSDPHINRFIKYLMMFLITMLILTSANNLFQLFIGWEGVGIMSFLLIGWWYGRADANTAALQAILYNRVGDIGFILAMTWFCLNMNSWELQQIFLT-NTN-NLVPLTGLLIAATGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLMIRFHPLTSNNSTIMTAMLCLGAITTLFTAICALTQNDIKKIVAFSTSSQLGLMMVTLGINQPYLAFLHICTHAFFKAMLFMCSGSIIHSLNDEQDIRKMGNMMKAMPFTSSCLIIGSLALTGMPFLTGFYSKDLIIEAINTCNTNAWALMITLIATSMTAVYSMRIIYFVTMTKPRYSPLITINENNPNLINPIKRLALGSILAGFLISLNIPPTNIQILTMPWHLKMTALLITILGFAIALELNN-LTLNLSMS-KPTKLSSFSTSLGYYPPIMHRIIPQKTLNSSYKLSLNLLDLIWLEKTIPKSTSITQTQLSKMMSNQ-KGLIKLYFLSFLITISLIFILHTLNPEWFQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P03921-1", "uniprot_id": "NU5M_MOUSE", "id": "P03921-1", "name": "NADH-ubiquinone oxidoreductase chain 5", "aln": "MN--IFTTSILLIFILLLSPILISMSNLIKHINFPLYTTTSIKFSFIISLLPLLMFFHNNMEYMITTWHWVTMNSMELKMSFKTDFFSILFTSVALFVTWSIMQFSSWYMHSDPNINRFIKYLTLFLITMLILTSANNMFQLFIGWEGVGIMSFLLIGWWYGRTDANTAALQAILYNRIGDIGFILAMVWFSLNMNSWELQQIMFS-NNNDNLIPLMGLLIAATGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLVRFHPLTTNNNFILTTMLCLGALTTLFTAICALTQNDIKKIIAFSTSSQLGLMMVTLGMNQPHLAFLHICTHAFFKAMLFMCSGSIIHSLADEQDIRKMGNITKIMPFTSSCLVIGSLALTGMPFLTGFYSKDLIIEAINTCNTNAWALLITLIATSMTAMYSMRIIYFVTMTKPRFPPLISINENDPDLMNPIKRLAFGSIFAGFVISYNIPPTSIPVLTMPWFLKTTALIISVLGFLIALELNN-LTMKLSMN-KANPYSSFSTLLGFFPSIIHRITPMKSLNLSLKTSLTLLDLIWLEKTIPKSTSTLHTNMTTLTTNQ-KGLIKLYFMSFLINIILIIILYSINLE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P03915-1", "uniprot_id": "NU5M_HUMAN", "id": "P03915-1", "name": "NADH-ubiquinone oxidoreductase chain 5", "aln": "MT--MHTTMTTLTLTSLIPPILTTLVNPNKKNSYPHYVKSIVASTFIISLFPTTMFMCLDQEVIISNWHWATTQTTQLSLSFKLDYFSMMFIPVALFVTWSIMEFSLWYMNSDPNINQFFKYLLIFLITMLILVTANNLFQLFIGWEGVGIMSFLLISWWYARADANTAAIQAILYNRIGDIGFILALAWFILHSNSWDPQQMALL-NANPSLTPLLGLLLAAAGKSAQLGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLIRFHPLAENSPLIQTLTLCLGAITTLFAAVCALTQNDIKKIVAFSTSSQLGLMMVTIGINQPHLAFLHICTHAFFKAMLFMCSGSIIHNLNNEQDIRKMGGLLKTMPLTSTSLTIGSLALAGMPFLTGFYSKDHIIETANMSYTNAWALSITLIATSLTSAYSTRMILLTLTGQPRFPTLTNINENNPTLLNPIKRLAAGSLFAGFLITNNISPASPFQTTIPLYLKLTALAVTFLGLLTALDLNY-LTNKLKMK-SPLCTFYFSNMLGFYPSITHRTIPYLGLLTSQNLPLLLLDLTWLEKLLPKTISQHQISTSIITSTQ-KGMIKLYFLSFFFPLILTLLLIT-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9MIY0-1", "uniprot_id": "NU5M_DANRE", "id": "Q9MIY0-1", "name": "NADH-ubiquinone oxidoreductase chain 5", "aln": "MTDMIMPLTLILIFAVLSYPLLKPKSYSKSNNSFQAWN--AVHVSFLISLIPLTMMLYKESDHVVMCWSWMNTQAFNVDLSFKFDYYSVTFTSIALFITWSILEFASWYMASYPQKELFYKYLLLFLMSMIILVTANNLFQLFIGWEGVGIMSFLLIGWWFGRTEANTASLQAVIYNRMGDIGFILTLAWMAMYLNSWDIQQIFILSKDFDMTIPQIGLIIAATGKSAQFTLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLIRLHPIMETNKLAPTICLCLGALTTLFAATCALTQNDIKKIVAFSTSSQLGLMMVAIGLNQPHLAFFHICTHAFFKAMLFLCSGAIIHSLNNEQDIRKMGGTYHTLPMTTNYLTIGKMALMGTPFLAGFFSKDAILEAMTTSHLNAWALTLTLIATSFTAVYSFRMIYLVCLGSPRHKTYETIDEN-HIPTNTIQRLAWGSIIAGLIISYTMIPLKTPILTMPIYLKLAAILVTLLGIILGLEIST-LANKINKNTTPGIPFHFSISLIFFP-ILHRLIPMRKLFMG-ESAATKIEKSWSELFGPCGIAFTLMTVATFVKDHRMASIKSYLAVFLTSIILKMMMLKLYT----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18932-1", "uniprot_id": "NU5M_DROME", "id": "P18932-1", "name": "NADH-ubiquinone oxidoreductase chain 5", "aln": "-------------MCSISFVNLISMS---------------------LSCFLLSLYFLLNDMIYFIEWELVSLNSMSIVMTFLFDWMSLLFMSFVLMISSLVIFYSKEYMMNDNHINRFIMLVLMFVLSMMLLIISPNLISILLGWDGLGLVSYCLVIYFQN-IKSYNAGMLTALSNRIGDVALLLSIAWMLNYGSWNYIFYLEIMQNEFEMLMIGSLVMLAAMTKSAQIPFSSWLPAAMAAPTPVSALVHSSTLVTAGVYLLIRFN-IILSTSWLGQLMLLLSGLTMFMAGLGANFEFDLKKIIALSTLSQLGLMMSILSMGFLKLAMFHLLTHALFKALLFMCAGAIIHNMNNSQDIRLMGGLSIHMPLTSACFNVSNLALCGMPFLAGFYSKDMILEIVSISNVNMFSFFLYYFSTGLTVSYSFRLVYYSMTGDLNCGSLNMLNDESWIMLRGMMGLLIMSIIGGSMLNWLIFPFP-YMICLPIYMKLLTLFVCIVGGLFGYLISLSNLFFLNKSLFMYNLSTFLGSMWFMPYISTYGMIFYPLNYG-QLVVKSFDQGWSEYFGGQHLYQKLSMYSKTLFLMHNNSLKIYLLLFVFWILILLILLFL------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . :* : : : : . * . :: .: ::* *: *: * ...*::: :: :: ** . : : * : :*:::*::* : *::.:::**:*:*::*: *: :: .: .*.: : : **:**:.::*::.*: . : : : :::** ****: : .***:** .*******:****:*.**::*::*:: : .. * *..:* :::. * : *:***:*:** ******* :.:. **::*: ***:***:**:*:*:***.: :.**** **. :*:*: : :..:** * ***:**:*** *:* . . * ::: : ::*.:* ** *:: . . . :::: . : * *::.* ::. : * :* .:* :: : .:* . :. :. . * : : * * * . : :: * * : :* *: *. : : ::: ", "identical_positions": 131, "similar_positions": 190, "identity": "21.27%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011205-14", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05503-1", "uniprot_id": "COX1_RAT", "id": "P05503-1", "name": "Cytochrome c oxidase subunit 1", "aln": "MLVNRWLFSTNHKDIGTLYLLFGAWAGMVGTALSILIRAELGQPGA--LLGDDQIYNVIVTAHAFVMIFFMVMPMMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHVVTYYSGKKEPFGYMG-MVWAMMSIGFLGFIVWAHHMFTVGLDVDTRAYFTSAT--MIIAIPTGVKVFSWLATLHG------------------GNIKWSPAMLWALGFIFLFTVGG--------------------------------------------------------LTGIVLSN------SSLDIVLHDTYYVVAHFHYVLSMG--------AVFAIMAGFVHWFPLFSGYTLN-DTWAKAHFAIMFVGVNMTFFPQHFLG-LAGMPRRYSDYPDAYTTWN----TVSSMGSFIS-----------LTAVLVMIFMIWEAFAS-------KREVLSISY---------------SSTNLEWLHGCPPPYHTFEEPSYVKVK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00397-1", "uniprot_id": "COX1_MOUSE", "id": "P00397-1", "name": "Cytochrome c oxidase subunit 1", "aln": "MFINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSILIRAELGQPGA--LLGDDQIYNVIVTAHAFVMIFFMVMPMMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHVVTYYSGKKEPFGYMG-MVWAMMSIGFLGFIVWAHHMFTVGLDVDTRAYFTSAT--MIIAIPTGVKVFSWLATLHG------------------GNIKWSPAMLWALGFIFLFTVGG--------------------------------------------------------LTGIVLSN------SSLDIVLHDTYYVVAHFHYVLSMG--------AVFAIMAGFVHWFPLFSGFTLD-DTWAKAHFAIMFVGVNMTFFPQHFLG-LSGMPRRYSDYPDAYTTWN----TVSSMGSFIS-----------LTAVLIMIFMIWEAFAS-------KREVMSVSY---------------ASTNLEWLHGCPPPYHTFEEPTYVKVK------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00395-1", "uniprot_id": "COX1_HUMAN", "id": "P00395-1", "name": "Cytochrome c oxidase subunit 1", "aln": "MFADRWLFSTNHKDIGTLYLLFGAWAGVLGTALSLLIRAELGQPGN--LLGNDHIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSLLLLLASAMVEAGAGTGWTVYPPLAGNYSHPGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMG-MVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSAT--MIIAIPTGVKVFSWLATLHG------------------SNMKWSAAVLWALGFIFLFTVGG--------------------------------------------------------LTGIVLAN------SSLDIVLHDTYYVVAHFHYVLSMG--------AVFAIMGGFIHWFPLFSGYTLD-QTYAKIHFTIMFIGVNLTFFPQHFLG-LSGMPRRYSDYPDAYTTWN----ILSSVGSFIS-----------LTAVMLMIFMIWEAFAS-------KRKVLMVEE---------------PSMNLEWLYGCPPPYHTFEEPVYMKS-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9MIY8-1", "uniprot_id": "COX1_DANRE", "id": "Q9MIY8-1", "name": "Cytochrome c oxidase subunit 1", "aln": "MTITRWFFSTNHKDIGTLYLVFGAWAGMVGTALSLLIRAELSQPGA--LLGDDQIYNVIVTAHAFVMIFFMVMPILIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSGVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTTINMKPPTISQYQTPLFVWAVLVTAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHVVAYYAGKKEPFGYMG-MVWAMMAIGLLGFIVWAHHMFTVGMDVDTRAYFTSAT--MIIAIPTGVKVFSWLATLHG------------------GAIKWETPMLWALGFIFLFTVGG--------------------------------------------------------LTGIVLAN------SSLDIVLHDTYYVVAHFHYVLSMG--------AVFAIMAGFVHWFPLFTGYTLN-SVWTKIHFGVMFIGVNLTFFPQHFLG-LAGMPRRYSDYPDAYALWN----TVSSIGSLIS-----------LVAVIMFLFILWEAFTA-------KREVLSVEL---------------TATNVEWLHGCPPPYHTFEEPAFVQIQSN----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P00399-1", "uniprot_id": "COX1_DROME", "id": "P00399-1", "name": "Cytochrome c oxidase subunit 1", "aln": "--SRQWLFSTNHKDIGTLYFIFGAWAGMVGTSLSILIRAELGHPGA--LIGDDQIYNVIVTAHAFIMIFFMVMPIMIGGFGNWLVPLMLGAPDMAFPRMNNMSFWLLPPALSLLLVSSMVENGAGTGWTVYPPLSAGIAHGGASVDLAIFSLHLAGISSILGAVNFITTVINMRSTGISLDRMPLFVWSVVITALLLLLSLPVLAGAITMLLTDRNLNTSFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIISQESGKKETFGSLG-MIYAMLAIGLLGFIVWAHHMFTVGMDVDTRAYFTSAT--MIIAVPTGIKIFSWLATLHG------------------TQLSYSPAILWALGFVFLFTVGG--------------------------------------------------------LTGVVLAN------SSVDIILHDTYYVVAHFHYVLSMG--------AVFAIMAGFIHWYPLFTGLTLN-NKWLKSHFIIMFIGVNLTFFPQHFLG-LAGMPRRYSDYPDAYTTWN----IVSTIGSTIS-----------LLGILFFFFIIWESLVS-------QRQVIYPIQ---------------LNSSIEWYQNTPPAEHSYSELPLLTN-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00401-1", "uniprot_id": "COX1_YEAST", "id": "P00401-1", "name": "Cytochrome c oxidase subunit 1", "aln": "-MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVVGHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVESGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFGHPEVYILIIPGFGIISHVVSTYS-KKPVFGEIS-MVYAMASIGLLGFLVWSHHMYIVGLDADTRAYFTSAT--MIIAIPTGIKIFSWLATIHG------------------GSIRLATPMLYAIAFLFLFTMGG--------------------------------------------------------LTGVALAN------ASLDVAFHDTYYVVGHFHYVLSMG--------AIFSLFAGYYYWSPQILGLNYN-EKLAQIQFWLIFIGANVIFFPMHFLG-INGMPRRIPDYPDAFAGWN----YVASIGSFIA-----------TLSLFLFIYILYDQLVNGLNNKVNNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPAVHSFNTPAVQS--------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9ZZX1-1", "uniprot_id": "SCE4_YEAST", "id": "Q9ZZX1-1", "name": "Intron-encoded DNA endonuclease aI5 alpha", "aln": "-MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVVGHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVESGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFGHPEVYILIIPGFGIISHVVSTYS-KKPVFGEIS-MVYAMASIGLLGFLVWSHHMYIVGLDADTRAYFTSAT--MIIAIPTGIKIFSWLMNPFSKDKNKNKNKKLIRNYQKMNNNNMMKTYLNNNNMIMMNMYKGNLYDIYPRSNRNYIQPNNINKELVVYGYNLESCVGMPTYTNIVKHMVGIPNNILYIMTGILLTDGWIDYTSKKDLDKKTIMEINCRFRLKQSMIH--SEYLMYVFMLLSHYCMSYPKMKIAKVKGKSYNQLEFYTRSLPCFTILRYMFYNGRVKIVPNNLYDLLNYESLAH----MIMCDGSFVKGGGLYLNLQSFTTKELIFIMNILKIKFNLNCTLHKSRNKYTIYMR---------VESVKRLFPMIYKYILPSMRYKFDIMLWQKKYNMIN--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P03878-1", "uniprot_id": "SCE2_YEAST", "id": "P03878-1", "name": "Intron-encoded DNA endonuclease aI4", "aln": "-MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVVGHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVESGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFGQTVATIIMLMMYNDMHFSKCWKLLKKWITNIMSTLFKALFVKMFMSYNNQQDKMMNNTMLKKDNIKRSSETTRKMLNNSMNKKFNQWLAGLIDGDGYFG----------IVSKKYVSLEITVALEDEMALKEIQN------------------------------------------------------KFGGSIKLR------SGVKAIRYRLTNKTGMIKLINAVNGNIRNTKRLVQFNKVCILLGIDFIYPIKLTKDNSWFVGFFDADGTINYSFKNNHPQLTISVTNKYLQDVQEYKNILGGNIYFDKSQNGYYK----------WSIQSKDMVLNFINDYIKMNPSRTTKMNKLYLSK---------------EFYNLKELKAYNKSSDSMQYKAWLNFENKWKNK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*::*** ***..**:::. ::*: **::*::** **. ** * *:.:::**:*..**.:****:*** :******:*:***:**.* ****:**::**:** .: *:.*: ** ************:. :* *.****:**:***:.:**:***:***.* :**:. :: : *****::.:**.*********:..***** ***:**:**: :********:*******:. . *::: :. : . ** . :. :. *: ::.: .:* : . . :* * :: . . *. .** . : : * : . :: :: : : . . * : . : . * : .. :. : . . . : . . ", "identical_positions": 150, "similar_positions": 134, "identity": "23.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011205-16", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05505-1", "uniprot_id": "COX3_RAT", "id": "P05505-1", "name": "Cytochrome c oxidase subunit 3", "aln": "------MTHQTHAYHMVNPSPWPLTG--ALSALLLTSGLVMWFHYNSTILLSLGLLTNILTMYQWWRDIIREGTYQGHHTPIVQKGLRYGMILFIVSEVFFFAGFFWAFYHSSLVPTHDLGGCWPPTGITPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGNRNHMNQALLITILLGLYFTILQASEYFETSFSISDGIYGSTFFMATGFHGLHVIIGSTFLIVCLLRQLKFHFTSKHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00416-1", "uniprot_id": "COX3_MOUSE", "id": "P00416-1", "name": "Cytochrome c oxidase subunit 3", "aln": "------MTHQTHAYHMVNPSPWPLTG--AFSALLLTSGLVMWFHYNSITLLTLGLLTNILTMYQWWRDVIREGTYQGHHTPIVQKGLRYGMILFIVSEVFFFAGFFWAFYHSSLVPTHDLGGCWPPTGISPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGKRNHMNQALLITIMLGLYFTILQASEYFETSFSISDGIYGSTFFMATGFHGLHVIIGSTFLIVCLLRQLKFHFTSKHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00414-1", "uniprot_id": "COX3_HUMAN", "id": "P00414-1", "name": "Cytochrome c oxidase subunit 3", "aln": "------MTHQSHAYHMVKPSPWPLTG--ALSALLMTSGLAMWFHFHSMTLLMLGLLTNTLTMYQWWRDVTRESTYQGHHTPPVQKGLRYGMILFITSEVFFFAGFFWAFYHSSLAPTPQLGGHWPPTGITPLNPLEVPLLNTSVLLASGVSITWAHHSLMENNRNQMIQALLITILLGLYFTLLQASEYFESPFTISDGIYGSTFFVATGFHGLHVIIGSTFLTICFIRQLMFHFTSKHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9MIY4-1", "uniprot_id": "COX3_DANRE", "id": "Q9MIY4-1", "name": "Cytochrome c oxidase subunit 3", "aln": "------MAHQAHAYHMVDPSPWPLTG--AVAALLMSSGLAIWFHLHSMTLIVLGMILLILTMIQWWRDIIREGTFQGHHTPPVQKGLRYGMILFITSEVFFFLGFFWAFYHSSLAPTPELGGCWPPTGLTTLDPFEVPLLNTAVLLASGVTVTWAHHSLMEGERKQAIQSLALTILLGLYFTALQAMEYYEAPFTIADGVYGSTFFVATGFHGLHVIIGSTFLAVCLLRQVLFHFTSDHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P00417-1", "uniprot_id": "COX3_DROME", "id": "P00417-1", "name": "Cytochrome c oxidase subunit 3", "aln": "-----MSTHSNHPFHLVDYSPWPLTG--AIGAMTTVSGMVKWFHQYDISLFVLGNIITILTVYQWWRDVSREGTYQGLHTYAVTIGLRWGMILFILSEVLFFVSFFWAFFHSSLSPAIELGASWPPMGIISFNPFQIPLLNTAILLASGVTVTWAHHSLMENNHSQTTQGLFFTVLLGIYFTILQAYEYIEAPFTIADSIYGSTFFMATGFHGIHVLIGTTFLLVCLLRHLNNHFSKNHHFGFEAAAWYWHFVDVVWLFLYITIYWWGG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00420-1", "uniprot_id": "COX3_YEAST", "id": "P00420-1", "name": "Cytochrome c oxidase subunit 3", "aln": "MTHLERSRHQQHPFHMVMPSPWPIVVSFALLSLALSTALTMHGYIGNMNMVYLALFVLLTSSILWFRDIVAEATYLGDHTMAVRKGINLGFLMFVLSEVLIFAGLFWAYFHSAMSPDVTLGACWPPVGIEAVQPTELPLLNTIILLSSGATVTYSHHALIAGNRNKALSGLLITFWLIVIFVTCQYIEYTNAAFTISDGVYGSVFYAGTGLHFLHMVMLAAMLGVNYWRMRNYHLTAGHHVGYETTIIYTHVLDVIWLFLYVVFYWWGV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. *.:*:* ****:. *. :: :.:. : . :. *. : : *:**: *.*: * ** * *:. *:::*: ***::* .:***::**:: * **. *** *: ..:* ::***** :**:**.::*::**:*: .::.: ..* :*. * : *. * ** ::.*:*:*.:***.*: .**:* :*::: :::* : * *:: **.*:*:: * *.:**:*****: :**** ", "identical_positions": 90, "similar_positions": 95, "identity": "33.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011205-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P03889-1", "uniprot_id": "NU1M_RAT", "id": "P03889-1", "name": "NADH-ubiquinone oxidoreductase chain 1", "aln": "------MYFINILTLLIPILIAMAFLTLVERKILGYMQLRKGPNIVGPYGILQPFADAMKLFMKEPMRPLTTSMSLFIIAPTLSLTLALSLWIPLPMPHPLINLNLGMLFILATSSLSVYSILWSGWASNSKYSLFGALRAVAQTISYEVTMAIILLSVLLMSGSFSLQMLITTQEHIWLLIPAWPMAMMWYISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFMAEYTNIILMNALTSIVFLGPLYHINYPELYSTSFMTETLLLSTTFLWIRASYPRFRYDQLMHLLWKNFLPLTLAFCMWYISLPIFLAGIPPYT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P03888-1", "uniprot_id": "NU1M_MOUSE", "id": "P03888-1", "name": "NADH-ubiquinone oxidoreductase chain 1", "aln": "------MFFINILTLLVPILIAMAFLTLVERKILGYMQLRKGPNIVGPYGILQPFADAMKLFMKEPMRPLTTSMSLFIIAPTLSLTLALSLWVPLPMPHPLINLNLGILFILATSSLSVYSILWSGWASNSKYSLFGALRAVAQTISYEVTMAIILLSVLLMNGSYSLQTLITTQEHMWLLLPAWPMAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFMAEYTNIILMNALTTIIFLGPLYYINLPELYSTNFMMEALLLSSTFLWIRASYPRFRYDQLMHLLWKNFLPLTLALCMWHISLPIFTAGVPPYM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P03886-1", "uniprot_id": "NU1M_HUMAN", "id": "P03886-1", "name": "NADH-ubiquinone oxidoreductase chain 1", "aln": "------MPMANLLLLIVPILIAMAFLMLTERKILGYMQLRKGPNVVGPYGLLQPFADAMKLFTKEPLKPATSTITLYITAPTLALTIALLLWTPLPMPNPLVNLNLGLLFILATSSLAVYSILWSGWASNSNYALIGALRAVAQTISYEVTLAIILLSTLLMSGSFNLSTLITTQEHLWLLLPSWPLAMMWFISTLAETNRTPFDLAEGESELVSGFNIEYAAGPFALFFMAEYTNIIMMNTLTTTIFLGTTYDALSPELYTTYFVTKTLLLTSLFLWIRTAYPRFRYDQLMHLLWKNFLPLTLALLMWYVSMPITISSIPPQT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9MIZ0-1", "uniprot_id": "NU1M_DANRE", "id": "Q9MIZ0-1", "name": "NADH-ubiquinone oxidoreductase chain 1", "aln": "MLDILTSHLINPLAYAVPVLIAVAFLTLVERKVLGYMQLRKGPNVMGPRGLLQSVADGVKLFIKEPIRPSMASPILFLTAPVLALILAMMLWAPMPMPYPVLDLNLGILFIMAISSLAVYSILGSGWASNSKYALIGALRAVAQTISYEVSLGLILLSAVIFSGGYTLQTFNTTQEDTWLLLPLWPLAIMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFLAEYSNILLMNTHSTVLFLGASFTPDAPELMTISIATKTAMLSILFLWMRASYPRFRYDQLMHLIWKNFLPITLVLVLWHIALPIALAGLPPQT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18929-1", "uniprot_id": "NU1M_DROME", "id": "P18929-1", "name": "NADH-ubiquinone oxidoreductase chain 1", "aln": "--MEFILSLIGSLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGLMGIPQPFCDAIKLFTKEQTYPLLSNYLSYYISPIFSLFLSLFVWMCMPFFVKLYSFNLGGLFFLCCTSLGVYTVMVAGWSSNSNYALLGGLRAVAQTISYEVSLALILLSFIFLIGSYNMIYFFFYQVYMWFLIILFPMALVWMSISLAETNRTPFDFAEGESELVSGFNVEYSSGGFALIFMAEYASILFMSMLFCVIFLG-------CDVFNLLFYMKLTFISFVFIWVRGTLPRFRYDKLMYLAWKCFLSFSLNYLLFFIGFKILLFSLL---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * : :*:::*** * ***:***:*:***** :* *: *...*.:*** ** * :. : :* ::* ::: :* :*: : .:*** **::. :**.**::: :**:***:*:*:*.************::.:**** ::: *.:.: : * *:*: :*:*::* :******:***::***********:**::* ***:*:***:.*::*. :*** :: . : : ::: *:*:* : ******:**:* ** **.::* ::.:.: * .: ", "identical_positions": 125, "similar_positions": 103, "identity": "38.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011205-8", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P11662-1", "uniprot_id": "NU2M_RAT", "id": "P11662-1", "name": "NADH-ubiquinone oxidoreductase chain 2", "aln": "-MNPITLIIIYFTILMGPVITMSSSNLLLMWVGLEMSLLAIIPLLANKKSPRSTEAATKYFLTQATASMIILLVIILNYKQSGMWTLQQQTNNMLLNMMLISLAMKLGLAPFHYWLPEVTQGIPLHIGLILLTWQKIAPLSILYQFYQLLNPTITTILAISSVFVGAWGGLNQTQTRKIMAYSSIAHMGWMTAILPYNPNLTLLNLTIYILLTVPMFITLMTNSATTINTLSLAWNKTPMILTMTSIILLSLGGLPPLTGFLPKWAIISELLKNNCSTLSTLMAIMALLSLFFYTRLIYSMSLTMFPTNNNSKMISHHHQNPKHNFILPTLTVLSTLTLPLSSQLIT---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P03893-1", "uniprot_id": "NU2M_MOUSE", "id": "P03893-1", "name": "NADH-ubiquinone oxidoreductase chain 2", "aln": "-MNPITLAIIYFTIFLGPVITMSSTNLMLMWVGLEFSLLAIIPMLINKKNPRSTEAATKYFVTQATASMIILLAIVLNYKQLGTWMFQQQTNGLILNMTLMALSMKLGLAPFHFWLPEVTQGIPLHMGLILLTWQKIAPLSILIQIYPLLNSTIILMLAITSIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLAILPYNPSLTLLNLMIYIILTAPMFMALMLNNSMTINSISLLWNKTPAMLTMISLMLLSLGGLPPLTGFLPKWIIITELMKNNCLIMATLMAMMALLNLFFYTRLIYSTSLTMFPTNNNSKMMTHQTKT-KPNLMFSTLAIMSTMTLPLAPQLIT---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P03891-1", "uniprot_id": "NU2M_HUMAN", "id": "P03891-1", "name": "NADH-ubiquinone oxidoreductase chain 2", "aln": "-MNPLAQPVIYSTIFAGTLITALSSHWFFTWVGLEMNMLAFIPVLTKKMNPRSTEAAIKYFLTQATASMILLMAILFNNMLSGQWTMTNTTNQYSSLMIMMAMAMKLGMAPFHFWVPEVTQGTPLTSGLLLLTWQKLAPISIMYQISPSLNVSLLLTLSILSIMAGSWGGLNQTQLRKILAYSSITHMGWMMAVLPYNPNMTILNLTIYIILTTTAFLLLNLNSSTTTLLLSRTWNKLTWLTPLIPSTLLSLGGLPPLTGFLPKWAIIEEFTKNNSLIIPTIMATITLLNLYFYLRLIYSTSITLLPMSNNVKMKWQFEHT-KPTPFLPTLIALTTLLLPISPFMLMIL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9MIY9-1", "uniprot_id": "NU2M_DANRE", "id": "Q9MIY9-1", "name": "NADH-ubiquinone oxidoreductase chain 2", "aln": "-MNPYVLMILMSSLGLGTTLTFSSSHWILAWMGLEINTLAIVPLMAQQHHPRAVEATTKYFLIQAAAAAMILFTSTTNAWISGQWDVTGMPGPATSTAMMFALALKIGLAPMHFWLPEVLQGLDLLTGLILSTWQKLAPMALIIQTTQTTDPLILTSLGIASSLIGGWSGLNQTQLRKILAYSSIAHMGWMIIVIQYAPQLTLIALGTYIFMTSAAFLTLKVLSATKINTLTTTWPKSPILAAIATLVMLSLGGLPPLTGFMPKWLILQELTKQDLPATATIMALTALLSLFFYLRLCHAMTLTTSPNTINSAPHWRVQTT-QNSLPLTISVTVTMGLLPLTPAILMLTT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P03896-1", "uniprot_id": "NU2M_DROME", "id": "P03896-1", "name": "NADH-ubiquinone oxidoreductase chain 2", "aln": "MFNNSSKILFITIMIIGTLITVTSNSWLGAWMGLEINLLSFIPLLSDNNNLMSTEASLKYFLTQVLASTVLLFSSILLMLKNNMNNEINES--FTSMIIMSALLLKSGAAPFHFWFPNMMEGLTWMNALMLMTWQKIAPLMLISYLN---IKYLLLISVILSVIIGAIGGLNQTSLRKLMAFSSINHLGWMLSSLMISESIWLIYFFFYSFLSFVLTFMFNIFKLFHLNQLFSWFVNSKILKFTLFMNFLSLGGLPPFLGFLPKWLVIQQLTLCNQYFMLTLMMMSTLITLFFYLRICYSAFMMNYFENNWIMKMNMNSINYNMYMIMTFFSIFGLFLISLFYFMF----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :: : *. :* *. : *:***:. *:::*:: .: :.**: ***: *. *: ::*: . . : :: :* * **:*:*.*:: :* .*:* ****:**: :: : * * : *. .*****. **::*:*** *:*** : .: :: : * ::: : : . : : : : :********: **:*** :: :: : *:* :*:.*:** *: :: : . . : :. . :.: :: ", "identical_positions": 73, "similar_positions": 98, "identity": "20.86%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011205-9", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05506-1", "uniprot_id": "NU3M_RAT", "id": "P05506-1", "name": "NADH-ubiquinone oxidoreductase chain 3", "aln": "-MN-LLIIITINITLSFILISIAFWLPQMNLYSEKANPYECGFDPTSSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAIQTTNTTTMMATAFILVTILALGLSYEWTQKGLEWTE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P03899-1", "uniprot_id": "NU3M_MOUSE", "id": "P03899-1", "name": "NADH-ubiquinone oxidoreductase chain 3", "aln": "-MN-LYTVIFINILLSLTLILVAFWLPQMNLYSEKANPYECGFDPTSSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAIQTIKTSTMMIMAFILVTILSLGLAYEWTQKGLEWTE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P03897-1", "uniprot_id": "NU3M_HUMAN", "id": "P03897-1", "name": "NADH-ubiquinone oxidoreductase chain 3", "aln": "-MN-FALILMINTLLALLLMIITFWLPQLNGYMEKSTPYECGFDPMSPARVPFSMKFFLVAITFLLFDLEIALLLPLPWALQTTNLPLMVMSSLLLIIILALSLAYEWLQKGLDWTE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9MIY3-1", "uniprot_id": "NU3M_DANRE", "id": "Q9MIY3-1", "name": "NADH-ubiquinone oxidoreductase chain 3", "aln": "-MNLFATILIIMTTLSLVLALVSFWLPQMNSDTEKLSPYECGFDPLGSARLPFSLRFFLVAVLFPLFDLEIALLLPLPWGDQLNNPMETLFWAMTVLILLTLGLAYEWAQGGLEWAE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18930-1", "uniprot_id": "NU3M_DROME", "id": "P18930-1", "name": "NADH-ubiquinone oxidoreductase chain 3", "aln": "MFSIIFIALLILLITTIVMFLASILSKKALIDREKSSPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVEIALILPMIIIMKYSNIMIWTITSIIFILILLIGLYHEWNQGMLNWSN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : : * :: : :: : ** .*:****** ..:*:***::***::: * :**:****:**: : : :: .: :* :.* :** * *:*::", "identical_positions": 33, "similar_positions": 38, "identity": "28.21%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011212-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0R9-1", "uniprot_id": "FADS2_MOUSE", "id": "Q9Z0R9-1", "name": "Acyl-CoA 6-desaturase", "aln": "-------------------------------MGKG------GNQGEGSTERQAPMP-------TFRWEEIQKHNLRT-DRWLVIDRKVYNVTKWSQRHPGGHRVIGHYSGEDATDAFRAFHLDLDFVGKFLKPLLIGELAPEEPSLDRGKSSQITEDFRALKKTAEDMNLFKTNHLFFFLLLSHIIVMESLAWFILSYFGTGWIPTLVTAFVLATSQAQAGWLQHDYGHLSVYKKSIWNHVVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDIKSLH-VFVLGEWQPLEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMISRRDWV-----DLAWAISYYMRFFYTYIPFYGILGALVFLNFIRFLESHWFVWVTQMNHLVMEIDLDHYRDWFSSQLAATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALIDIVSSLKKSGELWLDAYLHK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z122-1", "uniprot_id": "FADS2_RAT", "id": "Q9Z122-1", "name": "Acyl-CoA 6-desaturase", "aln": "-------------------------------MGKG------GNQGEGSTELQAPMP-------TFRWEEIQKHNLRT-DRWLVIDRKVYNVTKWSQRHPGGHRVIGHYSGEDATDAFRAFHLDLDFVGKFLKPLLIGELAPEEPSLDRGKSSQITEDFRALKKTAEDMNLFKTNHLFFFLLLSHIIVMESIAWFILSYFGNGWIPTVITAFVLATSQAQAGWLQHDYGHLSVYKKSIWNHIVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDIKSLH-VFVLGEWQPLEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIRRRDWV-----DLAWAISYYARFFYTYIPFYGILGALVFLNFIRFLESHWFVWVTQMNHIVMEIDLDHYRDWFSSQLAATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIVSSLKKSGELWLDAYLHK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95864-1", "uniprot_id": "FADS2_HUMAN", "id": "O95864-1", "name": "Acyl-CoA 6-desaturase", "aln": "-------------------------------MGKG------GNQGEGAAEREVSVP-------TFSWEEIQKHNLRT-DRWLVIDRKVYNITKWSIQHPGGQRVIGHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLH-VFVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWV-----DLAWAVSYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAYLHK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q920L1-1", "uniprot_id": "FADS1_MOUSE", "id": "Q920L1-1", "name": "Acyl-CoA (8-3)-desaturase", "aln": "-------------------------------MAPD------PVPTPGPASAQLRQTR------YFTWEEVAQRSGREKERWLVIDRKVYNISDFSRRHPGGSRVISHYAGQDATDPFVAFHINKGLVRKYMNSLLIGELAPEQPSFEPTKNKALTDEFRELRATVERMGLMKANHLFFLVYLLHILLLDVAAWLTLWIFGTSLVPFILCAVLLSTVQAQAGWLQHDFGHLSVFGTSTWNHLLHHFVIGHLKGAPASWWNHMHFQHHAKPNCFRKDPDINMHPLFFALGKVLPVELGREKKKHMPYNHQHKYFFLIGPPALLPLYFQWYIFYFVVQRKKWV-----DLAWMLSFYARIFFTYMPLLGLKGFLGLFFIVRFLESNWFVWVTQMNHIPMHIDHDRNVDWVSTQLQATCNVHQSAFNNWFSGHLNFQIEHHLFPTMPRHNYHKVAPLVQSLCAKYGIKYESKPLLTAFADIVYSLKESGQLWLDAYLHQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q920R3-1", "uniprot_id": "FADS1_RAT", "id": "Q920R3-1", "name": "Acyl-CoA (8-3)-desaturase", "aln": "-------------------------------MAPD------PVQTPDPASAQLRQMR------YFTWEEVAQRSGREKERWLVIDRKVYNISDFSRRHPGGSRVISHYAGQDATDPFVAFHINKGLVRKYMNSLLIGELAPEQPSFEPTKNKALTDEFRELRATVERMGLMKANHLFFLFYLLHILLLDVAAWLTLWIFGTSLVPFTLCAVLLSTVQAQAGWLQHDFGHLSVFSTSTWNHLVHHFVIGHLKGAPASWWNHMHFQHHAKPNCFRKDPDINMHPLFFALGKVLSVELGKEKKKHMPYNHQHKYFFLIGPPALLPLYFQWYIFYFVVQRKKWV-----DLAWMLSFYVRVFFTYMPLLGLKGLLCLFFIVRFLESNWFVWVTQMNHIPMHIDHDRNVDWVSTQLQATCNVHQSAFNNWFSGHLNFQIEHHLFPTMPRHNYHKVAPLVQSLCAKYGIKYESKPLLTAFADIVYSLKESGQLWLDAYLHQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60427-1", "uniprot_id": "FADS1_HUMAN", "id": "O60427-1", "name": "Acyl-CoA (8-3)-desaturase", "aln": "-------------------------------MAPD------PVAAET--AAQGPTPR------YFTWDEVAQRSGCE-ERWLVIDRKVYNISEFTRRHPGGSRVISHYAGQDATDPFVAFHINKGLVKKYMNSLLIGELSPEQPSFEPTKNKELTDEFRELRATVERMGLMKANHVFFLLYLLHILLLDGAAWLTLWVFGTSFLPFLLCAVLLSAVQAQAGWLQHDFGHLSVFSTSKWNHLLHHFVIGHLKGAPASWWNHMHFQHHAKPNCFRKDPDINMHPFFFALGKILSVELGKQKKKYMPYNHQHKYFFLIGPPALLPLYFQWYIFYFVIQRKKWV-----DLAWMITFYVRFFLTYVPLLGLKAFLGLFFIVRFLESNWFVWVTQMNHIPMHIDHDRNMDWVSTQLQATCNVHKSAFNDWFSGHLNFQIEHHLFPTMPRHNYHKVAPLVQSLCAKHGIEYQSKPLLSAFADIIHSLKESGQLWLDAYLHQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DEX7-1", "uniprot_id": "FADS2_DANRE", "id": "Q9DEX7-1", "name": "Acyl-CoA 6-desaturase", "aln": "-------------------------------MGGG------GQQTDRITDTNGRFS-------SYTWEEVQKHTKHG-DQWVVVERKVYNVSQWVKRHPGGLRILGHYAGEDATEAFTAFHPNLQLVRKYLKPLLIGELEASEPSQDRQKNAALVEDFRALRERLEAEGCFKTQPLFFALHLGHILLLEAIAFMMVWYFGTGWINTLIVAVILATAQSQAGWLQHDFGHLSVFKTSGMNHLVHKFVIGHLKGASAGWWNHRHFQHHAKPNIFKKDPDVNMLN-AFVVGNVQPVEYGVKKIKHLPYNHQHKYFFFIGPPLLIPVYFQFQIFHNMISHGMWV-----DLLWCISYYVRYFLCYTQFYGVFWAIILFNFVRFMESHWFVWVTQMSHIPMNIDYEKNQDWLSMQLVATCNIEQSAFNDWFSGHLNFQIEHHLFPTVPRHNYWRAAPRVRALCEKYGVKYQEKTLYGAFADIIRSLEKSGELWLDAYLNK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8K1P9-1", "uniprot_id": "FADS3_RAT", "id": "Q8K1P9-1", "name": "Fatty acid desaturase 3", "aln": "-------------------------------MGGV------GEPGGGPGPREGPAPLGAP-LPIFRWEQIRQHDLPG-DKWLVIERRVYDISRWAQRHPGGSRLIGHHSAEDATDAFHAFHQDLHFVRKFLKPLLIGELAPEEPSQDGAQNAQLIEDFRALRQAAEDMKLFEADTTFFALLLGHILAMELLAWLLVYLLGPGWVSSVLAALILAISQAQCWCLQHDLGHASIFPKSRWNHVAQQFVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAP-VFLLGESS-VEYGKKKRRYLPYNHQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWT-----DLLWAASFYSRFFLSYSPFYGATGTLLLFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWASSQLAATCNVEPSLFIDWFSGHLNFQIEHHLFPTMPRHNYRRVAPLVKAFCAKHGLHYEVKPFLTALVDIIGSLKKSGDIWLDAYLHQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJE7-1", "uniprot_id": "FADS3_MOUSE", "id": "Q9JJE7-1", "name": "Fatty acid desaturase 3", "aln": "-------------------------------MGGV------GEPGGGPGPREGPAPLGAP-LPIFRWEQIRQHDLPG-DKWLVIERRVYDISRWAQRHPGGSRLIGHHGAEDATDAFHAFHQDLHFVRKFLKPLLIGELAPEEPSQDGAQNAQLIEDFRALRQAAEDMKLFEADTTFFALLLGHILAMELLAWLIIYLLGPGWVSSILAALILAISQAQCWCLQHDLGHASIFTKSRWNHVAQQFVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAP-VFLLGESS-VEYGKKKRRYLPYNHQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWT-----DLLWAASFYSRFFLSYSPFYGATGTLLLFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWASSQLAATCNVEPSLFIDWFSGHLNFQIEHHLFPTMPRHNYRRVAPLVKAFCAKHGLHYEVKPFLTALVDIIGSLKKSGDIWLDAYLHQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5Q0-1", "uniprot_id": "FADS3_HUMAN", "id": "Q9Y5Q0-1", "name": "Fatty acid desaturase 3", "aln": "-------------------------------MGGV------GEPG----PREGPAQPGAP-LPTFCWEQIRAHDQPG-DKWLVIERRVYDISRWAQRHPGGSRLIGHHGAEDATDAFRAFHQDLNFVRKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQAAEDMKLFDASPTFFAFLLGHILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWCLQHDLGHASIFKKSWWNHVAQKFVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAP-VFLLGESS-VEYGKKKRRYLPYNQQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWA-----DLLWAASFYARFFLSYLPFYGVPGVLLFFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQLAATCNVEPSLFTNWFSGHLNFQIEHHLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKPFLTALVDIVRSLKKSGDIWLDAYLHQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZCK6-1", "uniprot_id": "D3ZCK6_RAT", "id": "D3ZCK6-1", "name": "", "aln": "MKLEEKLEHNESLVGKSRPCLNDTHQANGKHIANGNLRANGNVEVYEKQEANGKGDRLRKCLNLYTWQEIQKH-NQETDQWLVIDRKVYNVTDWAGKHPGGHRVLNHYAGEDATDAFRAMHLDPSIVQLYLKPLLIGELSPEEPSQEKNKNPQLVEDFRELRKTLEDMNMFSANLWFFFLHLAQILILEVLAWLILRHFSSGWIVTILISFLLTVSQAQSSFLQHDIGHLSMFKKSKWNHLMHKFVMCHLKGLSADWWNYRHFQHHVKPNIYPKDPDIDVGP-LFLLGDTQPIKYGKKKIKYIDYEKQHLYFYMVALPLLMPVYFNLQSMQVMYLRKYWT-----DIVWVSSFYIRYFITFGPFYGIFGTVLLIYLVKFIESPWIAYVTQMSHIPMKMSREENLDWLSTQIVATCNIEQSFFNDWFTGHLNFQIEHHLFPTMPRHNYHKVAPLVKSLCTKHGLQYINKPILKAFGDIVRSLKKSAALWMDAYYE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0VAX3-1", "uniprot_id": "FS2P1_MOUSE", "id": "Q0VAX3-1", "name": "Fatty acid desaturase 2-like protein FADS2B", "aln": "MKLEEKLEHNESLVGKSRPCLHDTHQANGKPIANGNPTANGKVEVYEKQEANGKGNRLGKCLNLYTWQEIQRH-SQEADQWLVIDRKVYNVTDWAGKHPGGRRVLNHYAGQDATDAFRAMHLDLGMVKLYLKPLLIGELSPEEPSQEKNKNAQLVEDFRELRKTLEAMNMFSANLRFFFLHLAQILILEISAWLILHHFGSSWLVTILISFLLTVSQAQCSFLQHDLGHLSMFKKSKWNHLMHKFVMCHLKGLSADWWNYRHFQHHVKPNIYPKDPDIDVGP-LFLVGDTQPIKYGKKKIKYIDYEKQHLYFYMVALPFLMPVYFNLQSMQVMYLRKYWM-----DIAWVSSFYIRYFITFGPFYGIFGTVLLIYLVKFIESPWIAYVTQMSHIPMKMSSEENHDWLSTQVVATCNIEQSFFNDWFTGHLNFQIEHHLFPTMPRHNYHKVAPLVKSLCAKHGLQYINKPILKAFGDIVRSLKKSASLWMNAYYE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MWK0-1", "uniprot_id": "FS2P1_HUMAN", "id": "A8MWK0-1", "name": "Putative fatty acid desaturase 2-like protein FADS2B", "aln": "MKFEEKCGDNGSIVGRNQSYPGEKHQPKGKPIANG------EAEVYAKQEANGKCSTPRKSLSMYTWLEIQRH-NHEADQ-LVINCKVYNVSSWADRHPGGHQVLNHCAGEDAMDVFRAMHPELDIVQLYLKPLLIGELAPGEPSQERHKNSQLVKDFQELWSIAEAMNMFHANLGFFFLHFVQILILEVLAWLIVYHFGSGWPVTMFISFLLTISQASSSFLQHDAGHLSIFRKSKWNHVVHKFVMCHLKGLSADRWNYWHFEQHVKPNIYPKDPDIDTDP-LFLLGDSQPVKYGKKKIKYINYEEQHLYFYKVWLPLFMPVYLKLPSMQAMYLQRYWVCFSLQDITWVSSFYI-YFITFGLYYGIFGTMLLIYLVKFLESPWIVYVTQMSHITMRMSTEENRDWLTTQVLATCNTES-FFND-FTGHLNFQIEHHLFPTMPRHNYHKVAPLVRSLCAKHGLHYVNKPMLRAFGDIVRALKKSAALWADAYYE-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : : * :: : :: :*:: :**::: : :**** :::.* ..:** : * *:* : :* :::.****** . :** : . : .:*: * * : :. ** . : :*: :: *:: : :. . . :.:*: *:.. **** ** *:: .. **: ::**: :*** .* **. **::*.*** : ****: * :*. :: * :* ::: *:.** **: : * : : :: : : * *: * ::* * : * : :: ::.:** *:.::***.*: .:. : ** : *: **** . * : *:************* :**** : ** *:::* *:*: * *.: *: **: :*::*. :* :** . ", "identical_positions": 124, "similar_positions": 142, "identity": "25.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011212-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P58197-1", "uniprot_id": "AP2A_RAT", "id": "P58197-1", "name": "Transcription factor AP-2-alpha", "aln": "-----MLWKLTDNIKYED---------------------CEDRHDGTSNGTARLPQLGTVGQSPYTSAPPLSHT-PNADFQPPYFPPPYQP--IYPQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQESGLLHTHRGLPHQLSGLDPRRDYRRHEDLLHGPHGLGSG--LGD--LPIHS-LPHAIEDVPHVEDPGINIPDQTVIKKGPVSLSKSNSNAVSAIPINKDNLFG------GVVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSSPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAVAEFLNRQHSDPNEQVARKNMLLATKQICKEFTDLLAQDRSPLGNSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNNPNSHTDNSAKSSDKEEKHRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P34056-1", "uniprot_id": "AP2A_MOUSE", "id": "P34056-1", "name": "Transcription factor AP-2-alpha", "aln": "-----MLWKLTDNIKYED---------------------CEDRHDGTSNGTARLPQLGTVGQSPYTSAPPLSHT-PNADFQPPYFPPPYQP--IYPQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQESGLLHTHRGLPHQLSGLDPRRDYRRHEDLLHGPHALGSG--LGD--LPIHS-LPHAIEDVPHVEDPGINIPDQTVIKKGPVSLSKSNSNAVSAIPINKDNLFG------GVVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAVAEFLNRQHSDPNEQVARKNMLLATKQICKEFTDLLAQDRSPLGNSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNNPNSHTDNSAKSSDKEEKHRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05549-1", "uniprot_id": "AP2A_HUMAN", "id": "P05549-1", "name": "Transcription factor AP-2-alpha", "aln": "-----MLWKLTDNIKYED---------------------CEDRHDGTSNGTARLPQLGTVGQSPYTSAPPLSHT-PNADFQPPYFPPPYQP--IYPQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQESGLLHTHRGLPHQLSGLDPRRDYRRHEDLLHGPHALSSG--LGD--LSIHS-LPHAIEEVPHVEDPGINIPDQTVIKKGPVSLSKSNSNAVSAIPINKDNLFG------GVVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAVAEFLNRQHSDPNEQVTRKNMLLATKQICKEFTDLLAQDRSPLGNSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNNPNSHTDNNAKSSDKEEKHRK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B9E2-1", "uniprot_id": "A0A8M2B9E2_DANRE", "id": "A0A8M2B9E2-1", "name": "Transcription factor AP-2-alpha", "aln": "MENEQTRINMKNNEVDEHPVNSKNVPAQMPSAFAGFSPESEDRHDGTSNGTARLPQLGSVGQSPYTSAPPLSHT-PNSDFQPPYFPPPYQP--IYPQSQDPYSHVNDPYSINSLHAQSQPQHPGWPGQRQSQESSLLHQHRGLPHQLC-----REYRR-EVLLPSGHGIDTG--LTDS-IPIHG-IPHSLEDVQQVEDQGIHIPDQTVIKKGPVSISKNNSN-ISAIPINKDGLFG------GVVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAIAEYMNRQHSDPNEQVQRKNMLLATKQICKEFTDLLSQDRSPLGNSRPQPILEPGIQSCLTHFSLISHGFGTPAVCAALTALQNYLTEAIKAMDKMYLNNNPNSHSETGSKAGDKDEKHRK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PIH9-1", "uniprot_id": "M9PIH9_DROME", "id": "M9PIH9-1", "name": "", "aln": "----MHILHRTNDHQFEDQKFMMERLSGHGSLGLSSGSAAYTTHSGGHTGRSGPATGHSGHSSTHGSAATMHHQSLQSDFQPPYFPPPFHHSTQSPPQQQISGYLQNHGALEYLGTDPYGQPLSSLHHAPLHHYNQLAGLRSTQDQLGIHRTHREAELQGHVTQLSHGFPYTDRRSDYGSAISAGAAHGTRLGHEHESLALHQALQNAVDDVQAPALDDNVAFMSDLPLIKSMKSGKEAGNIGSGSPSEVFCAVPGRLSLLSSTSKYKVTIAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRLLREKLEKIGLNLPAGRRKAANVTLLTSLVEGEATHLAKDFHFVCETEFPARQLAEYIVRHQTEPQDSYRRKELILHSQQITKELMQILSQDRTTHFGTRSQHLLEPSMQRHLTHFSLITHGFGSPAIMAVLHAFQTFLNESLNYLEKLYPSNGGGMVSSSLDKSKIDNEKK--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:: *. . *.* .* : . : .*.: **..: * ::**********:: * .*: .:::: ::: * ::. * . : :. . * *. .** *: . : *.: * .* . .*. . . *. .:: . *..:.. .. ..* :* :*: *. * * .*.****:*****************:********.*********************** *****:***************************.***:** :********: :**:: *::::*::. **:::* ::** **: ::*:***:. .:*.: :***.:* ****.**:****:**: *.: *:*.:*.*::: ::*:* .*. . :.. *: .:**: ", "identical_positions": 180, "similar_positions": 134, "identity": "37.74%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011220-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O15534-1", "uniprot_id": "PER1_HUMAN", "id": "O15534-1", "name": "Period circadian protein homolog 1", "aln": "-------MSGPLEGADGGGDPRPGESFCPGGVPSPGPPQHRPCPGPSLADDTDANSNG-----SSGNESNGHESRGASQRSSHSSSSGNGKDSALLETTESSKSTNSQSPSPPSSSIAYSLLSASSEQDNPSTSGCSSEQSARARTQKELMTALRELKLRLPPERRGKGRSGTLATLQYALACVKQVQANQEYYQQWSLEEGEPCSMDMSTYTLEELEHITSEYTLQNQDTFSVAVSFLTGRIVYISEQAAVLLRCKRDVFRGTRFSELLAPQDVGVFYGSTAPSRLPTWGTGASAGSGLRDFTQEKSVFCRIRGGPDRDPGPRYQPFRLTPYVTKIRVSDGAPAQPCCLLIAERIHSGYEAPRIPPDKRIFTTRHTPSCLFQDVDERAAPLLGYLPQDLLGAPVLLFLHPEDRPLMLAIHKKILQLAGQPFDHSPIRFCARNGEYVTMDTSWAGFVHPWSRKVAFVLGRHKVRTAPLNEDVFTPPAPSPAPSLDTDIQELSEQIHRLLLQPVHSPSPTGLCGVGAVTSPGPLHSPGSSSDSNGGDAEG-PGPPAPVTFQQICKDVHLVKHQGQQLFIESRARPQSRPRLPATGTFKAKALPCQSPDPELEAGSAPVQAPLALVPEEAERKEASSCSYQQINCLDSILRYLESCNLPSTTKRKCASSSSYTTSSASDDDRQRTGPVSVGTKKDPPSAALSGEGATPRKEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESDIIMMEDLPGLAPG----PAPSPAPSPTVAPDPAPDAYRPVG-----------------LTKAVLSLHTQKEEQAFLSRFRDLGRLRGLDSSSTAP-----SALGERGCHHGPAPP-----SRRHHCRSKAKRSR--HHQNP-----------RAEAPCYVS--HPSPVPPSTPWPT--------PPATTPFP---AVVQPYPLPVFSPRGGPQP-LPPAPTSVPPAAFPAPLVTPMVALVLPNYLFPTPSS-----------------------------------------YPYGALQTPAE---------GPPTPASHSPSPSLPALAPSP-PHRPD-------------------SPLFNSRCSSPLQLNLLQLEELP--RAEGAAVAGGPGSSAGP------PPPSAEAAEPEARLAEVTESS--NQDALSGSSDLLELLLQEDSRSGTGSAASGSLGSGLGSGSGSGSHEGGSTSASITRSSQSSHTSKYFGSIDSSEAEAGAARGGAEPG-DQVIKYVLQDPIWLLMANADQRVMMTYQVPSRDMTSVLKQDRERLRAMQKQQPRFSEDQRRELGAVHSWVRKGQLPRALDVMACVDCGSSTQDPGHP-DDPLFSELDGLGLEPMEEGGGEQGSSGGGSGEGEGCEEAQG--GAKASSSQDLAMEEEEEGRSSSSPALPTAGNCTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35973-1", "uniprot_id": "PER1_MOUSE", "id": "O35973-1", "name": "Period circadian protein homolog 1", "aln": "-------MSGPLEGADGGGDPRPGEPFCPGGVPSPGAPQHRPCPGPSLADDTDANSNG-----SSGNESNGPESRGASQRSSHSSSSGNGKDSALLETTESSKSTNSQSPSPPSSSIAYSLLSASSEQDNPSTSGCSSEQSARARTQKELMTALRELKLRLPPERRGKGRSGTLATLQYALACVKQVQANQEYYQQWSLEEGEPCAMDMSTYTLEELEHITSEYTLRNQDTFSVAVSFLTGRIVYISEQAGVLLRCKRDVFRGARFSELLAPQDVGVFYGSTTPSRLPTWGTGTSAGSGLKDFTQEKSVFCRIRGGPDRDPGPRYQPFRLTPYVTKIRVSDGAPAQPCCLLIAERIHSGYEAPRIPPDKRIFTTRHTPSCLFQDVDERAAPLLGYLPQDLLGAPVLLFLHPEDRPLMLAIHKKILQLAGQPFDHSPIRFCARNGEYVTMDTSWAGFVHPWSRKVAFVLGRHKVRTAPLNEDVFTPPAPSPAPSLDSDIQELSEQIHRLLLQPVHSSSPTGLCGVGPLMSPGPLHSPGSSSDSNGGDAEG-PGPPAPVTFQQICKDVHLVKHQGQQLFIESRAKPPPRPRLLATGTFKAKVLPCQSPNPELEVAPVPDQASLALAPEEPERKETSGCSYQQINCLDSILRYLESCNIPSTTKRKCASSSSYTASSASDDDKQRAGPVPVGAKKDPSSAMLSGEGATPRKEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESDIIMMEDLPGLAPG----PAPSPAPSPTVAPDPTPDAYRPVG-----------------LTKAVLSLHTQKEEQAFLNRFRDLGRLRGLDTSSVAP-----SAPG---CHHGPIPP-----GRRHHCRSKAKRSRHHHHQTP-----------RPETPCYVS--HPSPVPSSGPWPP--------PPATTPFP---AMVQPYPLPVFSPRGGPQP-LPPAPTSVSPATFPSPLVTPMVALVLPNYLFPTPPS-----------------------------------------YPYGVSQAPVE---------GPPTPASHSPSPSLPPPPLSP-PHRPD-------------------SPLFNSRCSSPLQLNLLQLEESP--RTEGGAAAGGPGSSAGP------LPPSEETAEPEARLVEVTESS--NQDALSGSSDLLELLLQEDSRSGTGSAASGSLGSGLGSGSGSGSHEGGSTSASITRSSQSSHTSKYFGSIDSSEAEAGAARARTEPG-DQVIKCVLQDPIWLLMANADQRVMMTYQVPSRDAASVLKQDRERLRAMQKQQPRFSEDQRRELGAVHSWVRKGQLPRALDVTACVDCGSSVQDPGHS-DDPLFSELDGLGLEPMEEGGGEGGGCGVGGGGGDGGEEAQTQIGAKGSSSQDSAMEEEEQGGGSSSPALPAEENSTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4ICG0-1", "uniprot_id": "A0A0R4ICG0_DANRE", "id": "A0A0R4ICG0-1", "name": "", "aln": "MNNNNFQAPASCGGFADKAAIEMDEEEGQNNISPAMTDNQSLCPGLNITNESQQTHSGDTDAQSSGIDSTERENDGRLGHGTSTCSSLHGKGSAT-ETTES-KSSNGNSPSPPSSSVSFSLLSGSSEQDHSTSQASNSDQPARLQTQRELLKVLRELKIHMPAERRRKGRSSTLASLQYALSCVKQVRANQEYYHQWSVEESHGCCLDLSSFTIEELDNVTSEYTLQNTDTFSVAVSFLSGKVVYISSQAASLLRCKAERLQGALFSELLAPQDVSTFYSSTAPSRLPPWSSCAGTSS-QVDCAEEKSMFCRISRGRDSNGEVKYHPFRLTPYQLTLRDSDTSQPEPCCLLIAERVHSGYEAPRIPADKRIFTTSHTPNCLFQEIDERAVPLLGYLPQDLVGKPVLVYLHPEDRLLMVAIHKKILQFAGQPFDHSPLRMRARSGEYLTIDTSWSSFINPWSRKVAFIVGRHKVRTSPLNEDVFTAPEGEEMKTMSPDVPQLNELIHRFLVQPVYGGSSQGYGSLGSSGSHEHQQGATSSSESNGHTSEDQIKPRKPMTFEQICQDMHMVKTSGQQVFIESRNRPP----ALKQGSLEALAKAADT----AEASARDGLASLALSSP-PRKELPMIYSYQQINCLDSIVRYLESFNVPGTVKRKCGSSS-CTTSSTSDDDKQREG---AGATQAETLVVTEGSKVVP---AAPAHPLTPLALHCKAESVVSATSQCSFSSTIVHVGDKKPPESDIVMMEEPPTTPTASTSAPATSVASPIPVNPQPMPSPTAAVHEKEKEKERRSGGSAGKGLTKAVLSAHTQQEEQAFLNRFRDLSQLRMVQPSGLPPPRRCTSIPGTKGVNSSQNYPSVGNTSSRRHGRGGKRQKHQVDGNIPNNTPISASGPYRGPNPAQIRPNFPSVQQSSNSWAPSAASQTNGAPVGTSFPPSYMTMFPTSSPFSVTQMGTDPSLQTGVPRFPAQGFPS-VMPPVMTFMMPNYMFPQLSNPGSQLNPANSQLNAQMNSFGQFPPPVVQMSVPMFNPAMGQFYPLGSQMNPAMPAMIPQQFYNPNYQLNFSNSPSMPAANVSTTPHGQSRSSTPQSTGPQAGERDGAGSPLFQSRCSSP--LNLLQLEELPSNRTDATQQTPPPGGGATQGGVVVVQNSSNRSNTQDAKLNDHPEVSESNQDALSTSSDMLDLLLQEDSRSGTGSSGSGSGSGSFASGS-----NGCSTSGSGTRSS---NTSKYFGSIDSSENDQNHKPASGDLGGEQFIKFVLQDPIWLLMANTDDKIMMTYQIPIKDKDSVLKEDRDALKAAQKHQPHFTEEQKKELTQVHPWIQTGCLPKAINVTSCTGCESPPDSSTLPPFDLEFHEMD-LNVVLREEAKQED-------------KLAETAFPLSPPSSDN---EQRDNQANLST-----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... * . . . .* ..:... . :: *** .:::::: . .* *** :*. *. * :.: :.** :**.** ***** **:*.:********:::****.*****:.::....*:*.** :**:**:..*****:::*.*** ****.***:*****:*****:******:***:**.. *.:*:*::*:***:::******:* **********:*::****.**. ***** : ::*: **********..**.**:*****.*.: :.:.* * ::***:**** * * : :*:******* .:* ** : .:*********:**********.******* ***.****::****.**********:* ***::****** **:********:*********:*: **.***:*:****:.*::********::*******:********.* . ::..*: :*.* ***:*:***:. *. * .:*. * :.. ***:*** :*. * *:**:***:*:*:** .***:***** :* *:::* . ..:: *... *.*** . ..:: . ***********:***** *:*.*.****.*** *:**:****:** * .*:.: . . .*. ..* .. . .*:**** *******.***********************:***: * ... **.* *.. .* *:* *.. .* ******* ***:******.*****.:** ::.*. .* * * : . * . *:* *. ::.: . : * * *. : .** .* .*.. .*. *.** : * . *. .: *.:* * .. . ... **: ::.*::::::***:** .. ** * *. .* ..* ***:*. *. ** . ****:****** ******** * *::. : **..* .* .: :*:* : .* * ****** ***:*:*************:.*** ...:.*** :* ***.* **** :************ : . . : * :*.** ************:*:::*****:* :* ****:**: *:* **:**:*:*:*::** **.*::.* **:*::* :*..* *. :.. . * * *:* *.: **. * : *: . .**:: *:.:: . *: ", "identical_positions": 625, "similar_positions": 361, "identity": "43.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011220-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z301-1", "uniprot_id": "PER2_RAT", "id": "Q9Z301-1", "name": "Period circadian protein homolog 2", "aln": "-----------------------------MNGYVDFSP----SPTSPTQEPGEPQPTQ--------AVLQEDVDMSS--GSSG----------NENCSTGRDSQGSDCDDSG----KELRMLVES-----SNTH----PSPDDTFRLMMTEAEH-NPSTSGCSSEQSAKADAHKELIRTLRELKVHLPADKKAKG-KASTLATLKYALRSVKQVKAN------------EEYYQLLMSSESQPCSVDVPSYTMEQVEGITSEYIVKNSDMFAVAVSLVSGKILYISNQVAPIFHCKKDAFSDAKFVEFLAPHDVSVFHSYTTP-YKLPPWSVSSGLDSFTQECMEEKSFFCRVSVGK-HHENEIRYQPFRMTPYLVKVQEQKGAA-------SQLCCLLLAERVHSGYEAPRIPPEKR--IFTTTHTPNCLFQDVDERAVPLLGYLPQDLIETPVLVQLHPSDRPLMLAIHKKILQ---ASGQPFDYSPIRFRTRNGEYITLDTSWSSFINPWSRKISFIIGRHKVRVGPLNEDVFAASPCPEEKTPHPSVQELTEQIHRLLMQPVPHSGSSGYGSLGSNGSHEHLMSQTSSSDSNG------QEESHWRRSGIFKTSGKSQSKSHFSPESGGQKEASVAEMQSSPPAQVRSVTTMERDSSGASLPKASFPEELTYKSQPPCSYQQISCLDSVIRYLESCNEAATLKRKCEFPANIPS------RKATVSPGLHSGEAARSSKVTS-------------HTEVSAHLSSLALPGKAESVVSLTSQCSYSSTIVHVGDKKPQPE--------------LETVEDVAS--GPESQDDAAG-----GLSQEKGSLQKLGLTKEVLAAHTQREEQGFLQRFREVSRLGALQAHCQNYLQERSRAPASDR---GLRNASG----IESSWKKTGKNRKLKSKRVKTRDSSESTGSGGPVSHRPPLVGLNATAWSPSDTSQSSCPSAPFPAPVP-AYPLPVFPAPGIVSTPGTVVAPPAAAHTGFTMPVVPMGTQPEFAVQPLPFAAPLA-PVMAFMLPSYPFPPATPNLPQAFFPS-QPHFPAHPTLASEITPASQAEFPSRTSMLRQ--------------------PCACPVTPPAG--------------TVALG---RASPPLFQSRGSSPLQLNLLQLEEAPESSTGAAGTLG---TTGTAASGLDCTSGASRDRQPKAPPTCSE--PSDTQNSDAISTSSDLLNLLLGEDLCSATGSALSRSGASATSDSLGSSSLGCDTSRSGAGSSDTS------HTSKYFGSIDSSENNHKAKMITD----TEESEQFIKYVLQDPIWLLMANTDDNIMMTYQLPSRDLQAVLKEDQEKLKLLQRSQPHFTEGQRRELREVHPWVHTGGLPTAIDVTGCVYCESE-------EKGNLCLPYEEDSPSLGLCDTSEAKEEESGQLANPRKEAQT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54943-1", "uniprot_id": "PER2_MOUSE", "id": "O54943-1", "name": "Period circadian protein homolog 2", "aln": "-----------------------------MNGYVDFSP----SPTSPTKEPGAPQPTQ--------AVLQEDVDMSS--GSSG----------NENCSTGRDSQGSDCDDNG----KELRMLVES-----SNTH----PSPDDAFRLMMTEAEH-NPSTSGCSSEQSAKADAHKELIRTLKELKVHLPADKKAKG-KASTLATLKYALRSVKQVKAN------------EEYYQLLMSSESQPCSVDVPSYSMEQVEGITSEYIVKNADMFAVAVSLVSGKILYISNQVASIFHCKKDAFSDAKFVEFLAPHDVSVFHSYTTP-YKLPPWSVCSGLDSFTQECMEEKSFFCRVSVGK-HHENEIRYQPFRMTPYLVKVQEQQGAE-------SQLCCLLLAERVHSGYEAPRIPPEKR--IFTTTHTPNCLFQAVDERAVPLLGYLPQDLIETPVLVQLHPSDRPLMLAIHKKILQ---AGGQPFDYSPIRFRTRNGEYITLDTSWSSFINPWSRKISFIIGRHKVRVGPLNEDVFAAPPCPEEKTPHPSVQELTEQIHRLLMQPVPHSGSSGYGSLGSNGSHEHLMSQTSSSDSNG------QEESHRRRSGIFKTSGKIQTKSHVSHESGGQKEASVAEMQSSPPAQVKAVTTIERDSSGASLPKASFPEELAYKNQPPCSYQQISCLDSVIRYLESCSEAATLKRKCEFPANIPS------RKATVSPGLHSGEAARPSKVTS-------------HTEVSAHLSSLTLPGKAESVVSLTSQCSYSSTIVHVGDKKPQPE--------------LETVEDMAS--GPESLDGAAG-----GLSQEKGPLQKLGLTKEVLAAHTQKEEQGFLQRFREVSRLSALQAHCQNYLQERSRAQASDR---GLRNTSG----LESSWKKTGKNRKLKSKRVKTRDSSESTGSGGPVSHRPPLMGLNATAWSPSDTSQSSCPSAPFPTAVP-AYPLPVFQAPGIVSTPGTVVAPPAATHTGFTMPVVPMGTQPEFAVQPLPFAAPLA-PVMAFMLPSYPFPPATPNLPQAFLPS-QPHFPAHPTLASEITPASQAEFPSRTSTLRQ--------------------PCACPVTPPAG--------------TVALG---RASPPLFQSRGSSPLQLNLLQLEEAPEGSTGAAGTLG---TTGTAASGLDCTSGTSRDRQPKAPPTCNE--PSDTQNSDAISTSSDLLNLLLGEDLCSATGSALSRSGASATSDSLGSSSLGFGTSQSGAGSSDTS------HTSKYFGSIDSSENNHKAKMIPD----TEESEQFIKYVLQDPIWLLMANTDDSIMMTYQLPSRDLQAVLKEDQEKLKLLQRSQPRFTEGQRRELREVHPWVHTGGLPTAIDVTGCVYCESE-------EKGNICLPYEEDSPSPGLCDTSEAKEEEGEQLTGPRIEAQT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15055-1", "uniprot_id": "PER2_HUMAN", "id": "O15055-1", "name": "Period circadian protein homolog 2", "aln": "-----------------------------MNGYAEFPP----SPSNPTKEPVEPQPSQ--------VPLQEDVDMSS--GSSGH-------ETNENCSTGRDSQGSDCDDSG----KELGMLVEP-----PDAR----QSPD-TFSLMMAKSEH-NPSTSGCSSDQSSKVDTHKELIKTLKELKVHLPADKKAKG-KASTLATLKYALRSVKQVKAN------------EEYYQLLMSSEGHPCGADVPSYTVEEMESVTSEHIVKNADMFAVAVSLVSGKILYISDQVASIFHCKRDAFSDAKFVEFLAPHDVGVFHSFTSP-YKLPLWSMCSGADSFTQECMEEKSFFCRVSVRK-SHENEIRYHPFRMTPYLVKVRDQQGAE-------SQLCCLLLAERVHSGYEAPRIPPEKR--IFTTTHTPNCLFQDVDERAVPLLGYLPQDLIETPVLVQLHPSDRPLMLAIHKKILQ---SGGQPFDYSPIRFRARNGEYITLDTSWSSFINPWSRKISFIIGRHKVRVGPLNEDVFAAHPCTEEKALHPSIQELTEQIHRLLLQPVPHSGSSGYGSLGSNGSHEHLMSQTSSSDSNG------HEDSRRRRAEICKNGNKTKNRSHYSHESGEQKKKSVTEMQTNPPAEKKAVPAMEKDSLG-----VSFPEELACKNQPTCSYQQISCLDSVIRYLESCNEAATLKRKCEFPANVPALRSSDKRKATVSPGPHAGEAEPPSRVNS-------------RTGVGTHLTSLALPGKAESVASLTSQCSYSSTIVHVGDKKPQPE--------------LEMVEDAAS--GPESLDCLAGPALACGLSQEKEPFKKLGLTKEVLAAHTQKEEQSFLQKFKEIRKLSIFQSHCHYYLQERSKGQPSERTAPGLRNTSG----IDSPWKKTGKNRKLKSKRVKPRDSSESTGSGGPVSARPPLVGLNATAWSPSDTSQSSCPAVPFPAPVPAAYSLPVFPAP------GTVAAPPAPPHASFTVPAVPVDLQHQFAVQPPPFPAPLA-PVMAFMLPSYSFPSGTPNLPQAFFPS-QPQFPSHPTLTSEMASASQPEFPSRTSIPRQ--------------------PCACPATRATP--------------PSAMG---RASPPLFQSRSSSPLQLNLLQLEEAPEGGTGAMGTTG---ATETAAVGADCKPGTSRDQQPKAPLTRDE--PSDTQNSDALSTSSGLLNLLLNEDLCSASG--------SAASESLGSGSLGCDASPSGAGSSDTS------HTSKYFGSIDSSENNHKAKMNTG----MEESEHFIKCVLQDPIWLLMADADSSVMMTYQLPSRNLEAVLKEDREKLKLLQKLQPRFTESQKQELREVHQWMQTGGLPAAIDVAECVYCENK-------EKGNICIPYEEDIPSLGLSEVSDTKEDENGSPLNHRIEEQT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QFB2-1", "uniprot_id": "A0A8M9QFB2_DANRE", "id": "A0A8M9QFB2-1", "name": "Period circadian protein homolog 2", "aln": "MSEDLDSKPYLFSSLEGQDGAIGCSSMATLHRMASFAEGTELGLASEGSDSSQDRPTSGHNTRKMSHSLHEDVEMKSSSGSSGSGTESHGNESHGNESHGNESHGNESSGSSNSRSKDSALLVSSGSNKSSNSHSPSPPSSTNAFSLLSASSEQDNPSTSGCSSEESAKAKTQKELIKTLKELKLHLPAEKRNKGSKSTTLNTLKYALRCVRQVEAN------------EEYYQLLMINDSQPSGLDVSSYTIEEIDSITSEYTLKNTDIFAVAVSLITGKIVYISDQAASILNCKRDVFKNAKFVEFLTPQDVSVFYSFTTP-YRLPSWSMCTGADSSPSDCMQEKSFFCRISGGK-ECEADLQYYPFRMTPYLMKVQDMEHSE-------DQFCCLLLAERVHSGYEAPRIPTDKR--IFTTTHTPSCVFQDVDERAVPLLGYLPQDLIGTPVLLHLHPNDRPTMLGIHRKILQ---CAGQPFDHS-IRFCARNGEYITIDTSWSSFVNPWSRKVSFVIGRHKVRMGPVNEDVFAAPATAEGKCVDSDIQDITEQIHRLLLQPVHNNGSSGYGSLGSN---DHLLSVASSSESNGNGTRQRHEEEDIRKAKPRSFQEICKGVHMQKNQELQSKKSPTKFVQKSPVVRPKDSAYPVNWRESQEEQRAAVQEELAFKDQTVYSYQQISCLDSVIRYLESCNVPITVKRKCQSSSNTTSSNSDEDKQRNADSSMQVSEEPAHLKEQSGLSTLEVSKKPPGSGVVSPSLTPLALPSKPESVVSITSQCSYSSTIVHVGDKKVVSSTRHISTKQEYSSKLQKIIEDVPSAEGTDVQGLAVPPAAVSPQNQEREAYKKLGLTKQVLAAHTQKEEQAFLSRFRELRGVHAFKADCSLYLERQKGQVTSEAVPAARSCKAGGGGAQETTTTRRGRNKKTKSKRVKPNESSDSTPSGRRPAHRPQLQGLNQTSWSPSDTSQSTFP-IAYPAVMP-AYPLQMYPGA------GGMQPRVDAPMPGFGEGQCTPDPRIPMQPIQTPYSAPLVTPMVALVLPNYMFPQVGSAPRQAFYPPKQGPFPTQPTFQTQPGFTPQASFPPQTTFTIQTQFTSQNPFSSQPTFQPQPFPFACPEDPPKAPEPELREEQSRSPTPQSMGGGGPPSPPLFQSRCSSPLQLNLLQLEETQRSADRQENTAPSAVPLNNCSAGVEKAGSVTGQSKPVKDVVQDEGSPVDGQHSDALSSSSDLLDILP-EDSRSGTG--------SATSGSMGSGSNRCGTSASGGSASRTESSNKSNNSSNYFGSVDSSQKSHKAKAQGSGVLALDGSENLIKYVLQDPLWLLMANVDEDVMMSYQLPSRDIQKVLREDREKLRQMQKSQPRFTDEQKRELADVHPWMRRGGLPKAIDIKACMGCEELSEALNEDDPPDLHMGEAENSDVTAAPNSQELQEPPN-SPTHSCPGPDT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07663-1", "uniprot_id": "PER_DROME", "id": "P07663-1", "name": "Period circadian protein", "aln": "----------------MEGGESTESTHNTKVSDSAYSN----SCSNSQSQRSGSSKSR--------LSGSHSSGSSGYGGKPSTQASSSDMIIKRNKDKSRKKKKNKGAGQG---AGQAQTLISASTSLEGRDEEKPRPSGTGCVEQQICRELQDQQHGEDHSEPQAIEQLQQEEEEDQSGSESEADRVEGVAKSEAAQSFPIPSPLSVTIVPPSMGGCGGVGHAAGLDSGLAKFDKTWEAGPGKLESMTGVGAAAAGTGQRGERVKEDSFCCVISMHDGIVLYTTPSITDVLGYPRDMWLGRSFIDFVHLKDRATFASQITTGIPIAESRGSVPKDAKSTFCVMLRRYRGLKSGGFGVIGRPVSYEPFRLGLTFREAPEEARPDNYMVSNGTNMLLVICATPIKSSYKVPDEILSQKSPKFAIRHTATGIISHVDSAAVSALGYLPQDLIGRSIMDFYHHEDLSVMKETYETVMKKGQTAGASFCSKPYRFLIQNGCYVLLETEWTSFVNPWSRKLEFVVGHHRVFQGPKQCNVFEAAPTCKLKISEEAQSRNTRIKEDIVKR----------------------LAETVSRPSDT-----VKQEVSRRCQALASFMETLMDEVSRADLKLELPHENELTVSERDSVMLGEISPHHDYYDSKSSTETPPSYNQLNYNENLLRFFNSKPVTAPAELDPPKTEPPEPRGTCVSGASGPMSPVHEGSGGSGSSGNFTTASNIHMSSVT-------------NTSIAGTGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG-------------TGTGNGTNSGTGTGTASSSKG---------GSAAIPPVTLTESLLNKHNDEMEKFMLKKHRESRGRTGEKSKKSANDTLKMLEYSGPG----HGIKRG------GSHSWEGEANKPKQQLTLGTDAIKGAAGSAGGAVGTGGVGSGGAGVAGGGGSGTGVAGTPEGRATTTSGTGTPGGAGGGGGAGAAAAAGASSSVGSSTPGPSSYPTCTQNINLWPPFSVGITPPVHSTHTAMAQSSFSSAGLFPTFYYIPASLTPTSPTRSPRMHKHPHKGGTDMPTTSQQ---------------------AAAAAAQAMP--------------LQYMAGVMYPHPSLFYTHPAAAAATAMMYQPMPFPGMANALQIPERPLGSQSAYNKSVYTTTPASMTKKVPGAFHSVTTPAQVQRPSSQS-----------------------------ASVKTEPGSSAAVSDPCKKEVPDSS------PIPSVMGDYNSDPPCSSSNPANN-----------KKYTDSNGNSDDMDGSSFSSFYSSFIKTTDGSESPPDTEKDPKHRKLKSMSTSESKIMEHPEEDQTQHGDG----------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . :. .: : .. .. *... : * . ....: .. ... : *:.. . * . : : .. *. :: : ::* . . .: *. : :: . : . . . :: :. * : : . .. : * *. .:*: * ::* : . : :: :* : . .*::*: :* ..* * :. :. . *: . *: : : * : * ***: : :. : . :: :: * ::*.*:.* .:: *: **.. ::. **. **. ********* .:: * .* . * :..::: .* .* . ** :** *: ::*.*:**:******:.*::*:*:* ** : :** * . : * . . *. . :: : :: : * *: ::: * . . . :. . . . .. : .: : : . : : . . . . : .* :. . . ... : :. . : ... .. : *. : :.* . .* . :. * *. . . : **:.:* *.:. *: :*.:.:* ::. : .. * . . *. .* *.: . :: ..: .. : . * . :. : .. * : . . . : . . . . .. . . *:.. :. *: : . . . :* *: ** .. .: . .: * *.. . :. . *.** :: ::. :: . . .. : : . * : *...: * :* . ..* :. . . :. .. :*. :*. .:: . * . .: * . . . : : : : : . : .:. : : . :: : * : . : .* ", "identical_positions": 121, "similar_positions": 368, "identity": "8.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-011221-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A138-1", "uniprot_id": "D4A138_RAT", "id": "D4A138-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------PGVPTCVAATPFVRRAYAPRPPAHLPCLWPACLCARVLLPRLEGCVQPRSLPAPRVPLELQPGAPGLAGGPGRARPQLDPPAGAARGPRGRGRVAAGSNLSVLSRAGGWVGYGTPAERRALRRQRRDYLGLARLVGALHEE--------------EEPDVRLDPKPEPKPSSAS-QQASK------ESSAAPERLCSFCKHNGESRAIYQSHVLKDEAGRVLCPILRDYVCPQCGATQEHAHTRRFCPLTGQGYTSVYCYTTRNSAGKKLTRPDKAKTQNAGHRLGGEAAA----GSKSGRKPPGPSPSACCPSTTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60324-1", "uniprot_id": "NANO3_MOUSE", "id": "P60324-1", "name": "Nanos homolog 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGTFNLWT----------------DYLGLARLVGALHKE--------------EELDVRLDPKPEPKPSSES-QQASK------ESSAAPERLCSFCKHNGESRAIYQSHVLKDEAGRVLCPILRDYVCPQCGATQEHAHTRRFCPLTSQGYTSVYCYTTRNSAGKKLTRPDKAKTQDAGHRLGGEAAAGVYAGSKSGRKPPGPSPSACCPSTTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P60323-1", "uniprot_id": "NANO3_HUMAN", "id": "P60323-1", "name": "Nanos homolog 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGTFDLWT----------------DYLGLAHLVRALSGK--------------EGPETRLSPQPEPEPMLEPDQKRSL------ESSPAPERLCSFCKHNGESRAIYQSHVLKDEAGRVLCPILRDYVCPQCGATRERAHTRRFCPLTGQGYTSVYSHTTRNSAGKKLVRPDKAKTQDTGHRRGGGGGAG---FRGAGKSEPSPS---CSPSMST", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90WW1-1", "uniprot_id": "NANO3_DANRE", "id": "Q90WW1-1", "name": "Nanos homolog 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFSLLQFILSAHGSMETRNQDFQPWK----------------DYMGLADMIRGMKRQEMQSDADSD-----EQAAALLESPSGPIRSRDSPEQNTSPGGGKPKSSPAERKFCSFCKHNGETEAVYTSHYLKNRDGDVMCPYLRQYKCPLCGATGAKAHTKRFCPMVDKNYCSVYAKSTW------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25724-1", "uniprot_id": "NANOS_DROME", "id": "P25724-1", "name": "Protein nanos", "aln": "MFRSNLEGSGAAAVGVANPPSLAQSGKIFQLQDNFSAFHARGGLNILGLQDMYLDTSGANSSATLSPPITPVTPDPSTSAQSTHFPFLADSAATANSLLMQRQYHYHLLLQQQQQLAMAQHQLALAASAAAASASHQQTDEIARSLKIFAQVTTGAAENAAGSMQDVMQEFATNGYASDDLGRMSYGSAPPQVQMPPQQQHQQQQGLHLPLGRNPAQLQTNGGNLMPIPLATHWLNNYREHLNNVWRN--MSYIPAAPNTMGLQAQTAATVSTNLGVGMGLGLPVQGEQLRGASNSSNNNNNNNKVYKRYNSKAKEISRHCVFCENNNEPEAVINSHSVRDNFNRVLCPKLRTYVCPICGASGDSAHTIKYCPKKPIITMEDAIKAESFRLAKSSYYKQQMKV---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .*: * .: : . . . :: . ..: : * **::*.*..*: ** :::. . *:** ** * ** ***: *** ::** . : ", "identical_positions": 27, "similar_positions": 32, "identity": "6.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020104-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23899-1", "uniprot_id": "HNF1B_RAT", "id": "P23899-1", "name": "Hepatocyte nuclear factor 1-beta", "aln": "----MVSKLTSLQQELLSALLSSGVTKEVLIQALEELLPSP-NFGVKLETLPLSPGSG--ADLDTKPVFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQSSGN-MTDKSSQDQLLFLFPEFSQQNQGPGQS-EDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHNLNPLLTHGSPHH-QPSSSPPNKLSGVRYSQPGNNEVTSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHSLLSPDSKM-ISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQSLNTSQAQGVPVINSVASSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSINTLTSMSSSKQCPLQAW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P27889-1", "uniprot_id": "HNF1B_MOUSE", "id": "P27889-1", "name": "Hepatocyte nuclear factor 1-beta", "aln": "----MVSKLTSLQQELLSALLSSGVTKEVLIQALEELLPSP-NFGVKLETLPLSPGSG--ADLDTKPVFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQSSGN-MTDKSSQDQLLFLFPEFSQQNQGPGQS-EDTCSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHNLNPLLTHGSPHH-QPSSSPPNKMSGVRYNQPGNNEVTSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHSLLSPDSKMQITVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQSLNTSQAQGVPVINSVASSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSINTLTSMSSSKQCPLQAW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35680-1", "uniprot_id": "HNF1B_HUMAN", "id": "P35680-1", "name": "Hepatocyte nuclear factor 1-beta", "aln": "----MVSKLTSLQQELLSALLSSGVTKEVLVQALEELLPSP-NFGVKLETLPLSPGSG--AEPDTKPVFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQSSGN-MTDKSSQDQLLFLFPEFSQQSHGPGQS-DDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHSLNPLLSHGSPHH-QPSSSPPNKLSGVRYSQQGNNEITSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHNLLSPDGKM-ISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQSLNTSQAQSVPVINSVAGSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSISTLTNMSSSKQCPLQAW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L1N5-1", "uniprot_id": "HN1BA_DANRE", "id": "A1L1N5-1", "name": "Hepatocyte nuclear factor 1-beta-A", "aln": "MFANMVSKLTSLQQELLSALLDSGVTKDVLLQALEDLDPSPSAFGVKLDSLQMSPSGSKLSDTDSKPVFHTLTNGHSKGKLSGDEGSEDGDDYDTPPILKELQSQNTEEAAEQRAEIERMLAEDPWRAARMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQATQGSGATMLDKGNQDQVLLFFSEFSQSGQGMVQPGDDAAIEPACKKLRRNRFKWGPASQQILYQAYERQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSG-PAHSLNSLLSHSSPHHPQTSSSPPSKMQGVRYSQQGPGEVTSSTTINHHSSNAMSTSQSVLQQVSPGALDPSHSLLSPDAKM-ISVSGGGLPPVSTLTNIH-ASHHVHQQTPNLIM-PLSGVMAIAQSLNTSQAQTVPVINSVAGSLAALQPVQFSQQLNSQHQQ-LMQQSSG-HMSQQSFMASVS---HSHMYPHKQEPPQYSHSSRFPPAMVVTDANSLSTLSSMSSSKQCPLQAW", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****************.*****:**:****:* *** *****::* :**... :: *:***********:**:***********************: ***********::***:*******:**************************************************************:.*.** * **..***:*::*.****..:* *. :*:. **: **:*******************:********************************************************************. :*.**.**:*.**** *.*****.*:.****.* * .*:***:**.**...** ***********.:***.*.*****.** *:**************** *** **: **** ****************** ********.**************:* *** *****.* **:**.***:*: :****.**********:****.******:.*:.**:.************", "identical_positions": 447, "similar_positions": 81, "identity": "78.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020107-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18052-1", "uniprot_id": "PTPRA_MOUSE", "id": "P18052-1", "name": "Receptor-type tyrosine-protein phosphatase alpha", "aln": "----------------MDSWFILVLFGSGLIHVS-ANNATTVSPSLGTTRLIKTSTTELAKEENKTSNS-------------TSSVISLSVAPTFSPNLTLEPTYVTTVNSSHSDNGTRRAASTE--SGGTTISPNGSWLIENQFTDAITEPWEGN--SSTAATTPETFPP---------ADETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPFLSLAVSKDAVKALNKTTPLLERRFIGKSNSRGCLSDDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNVRVSVEDVTVLVDYTVRKFCIQQVGDVTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHSERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMINIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAFSDYANFK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18433-5", "uniprot_id": "PTPRA_HUMAN", "id": "P18433-5", "name": "Receptor-type tyrosine-protein phosphatase alpha", "aln": "----------------MDSWFILVLLGSGLICVS-ANNATTVAPSVGITRLINSSTAEPVKEEAKTSNP-------------TSSLTSLSVAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTN--SIGITISPNGTWLPDNQFTDARTEPWEGN--SSTAATTPETFPPSGNSDSKDRRDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPY------------------------------------DHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAFSDYANFK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QE38-1", "uniprot_id": "F1QE38_DANRE", "id": "F1QE38-1", "name": "Receptor-type tyrosine-protein phosphatase alpha", "aln": "MQVSFLQGSMGVCPLLLHVAFVALSTAQTLPHLSGAVQTTKPTPHPPTTPLIIVTNGSPTAAPTSTPSPQLIATKAFNDSEGTAAPEATTAPPVVPPPAVPIPTVVLPVPPTPTAASPSLTTNKTGDHQTTVLAPAGTPTPDPTSTQSSSEPETETPYTPADATTADVNKPEG-----EEQDDTAIMAVMVALSSLLVIVFIIIILYMLRFKKYKQAGSHSNSFRLTNGRADDTELQSVPLLARSPSTNRKYPPLPVDKLEEEMNRRMADDNKLFREEFNALPVCPIQASCDAASKEENKEKNRYVNILPY------------------------------------DHSRVHLTSLEGVPDSDYINASYINGYQEKNKFIAAQGPKEETVNDYWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDTMILVDYTIRKFCIQQVGDVSGKKPQRLVTQFHFTSWPDFGVPFTPIGMLKFLKKVKNCNPQYAGPIMVHCSAGVGRTGTFIVIDAMLDMMGAERKVDVFGFVTRIRAQRCQMVQTDMQYVFIFQALLEHYLYGDTELEVTSLETHMNKLYAPLPGAGCGGLEAEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYINASFIDGYRQKDSYMACQGPLQHTIEDYWRMIWEWRSCSIVMLTELEERGQEKCAQYWPTDGVMVCGDMSIELKREEESESYTVRDLLVTNNRENKSRAVRQFHFHGWPEVGIPSDGKGMINIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAFSDYANFK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. *: : .. * :* * ::*. :* * ** :. . . .*... *:: : :..*...* . ** : .* .: : .. ::.. .::* *: : *:: :** . :.: ***.:. * *:*.*:*****************:*********************:***::*.* ***************************:*******************.*****:*:******************: ********.:************:***********************:****************************************:******. :*****:**********::.:*****:**************************** *******.*:*************:********* :******:***:*******************:**********************::*:* :**:. .*** *****************************************************:**************:*.**** *****:*******:***********************:**:: **:::***:***.************.****** :*********************.*******************************************************************************************", "identical_positions": 612, "similar_positions": 111, "identity": "70.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020107-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2A8L5-1", "uniprot_id": "PTPRF_MOUSE", "id": "A2A8L5-1", "name": "Receptor-type tyrosine-protein phosphatase F", "aln": "---MAPEPAPGRRMVPLVPALVMLGLMAGAHGDSKPVFVKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVS--SQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLG-EINTSAKLSVLEEDQLPSGFPTIDMGPQLKVVEKGRTATMLCAAGGNPDPEISWFKDFLPVDPAASNGRIKQLRSG------ALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPP-SSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVMRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNTEPVSFYGIQYRAAGTDGPFQEVDGVASTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPLSAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQANAESDTRIQLSWLLPPQ--ERIVKYELVYWAAEDEGQQHKVTFDPTSSYTLEDLKPDTLYHFQLAARSDLGVGVFTPTVEARTAQSTPSAPPQKVTCVSTGSTTVRVSWVPPPADSRNGIITQYSVAYEAVDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVSWKLPVPNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLAEAQ---------ETTISGLTPETTYSITVAAYTTKGDGARSKPKVVTTTGAVPGRPTMMVSTTAMH---TALLQWHPPKELPGELLGYRLQYRRADEARPNTIDFGKDDQHFTVTGLHKGATYVFRLAAKNRAGPGEEFEKEITTPEDVPSGFPQNLRVTGLTTSTTELTWDPPVLAERNGHITNYTVVYR-DINSQLELQNVTNDTHLTLLGLKPDTTYDIKVRAHTSKGAGPLSPSIQSRTMPVEQ-VFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLI--------ADLQPNTEYSFVLMNRGSS-AGGLQHLVSIRTAPDLLPQKPLPASAFIEDG-RFSLSMPQVQDPS----------------------------LVRWFYIVVVPIDRVG----------------------GNLLAPRWNTPE---------ELELDELLEAIEQGEEKQ-------------------------------RRRRRQAERLKPYVAAQVD--VLPDTFTLGDKKSYRGFYNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTP----------------------AQQQEEPEMLWVTGPVLAVILIILIVIAILLFKRKRTHSPSSKDEQSIG---LKDSLLAHS--SDPVEMRRLNYQTPG-----------MRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNSEVNKPKNRYANVIAYDHSRVLLTSIDG--VPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQR---TATVVMMTRLEEKSRVKCDQYWPVRGTETYGLIQVTLVDTVELATYTMRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAMCGHTEVLARNLYAHIQKLGQVPPGESVTAMELEFKLLANSKAHTSRFVSANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIG--------QVHKTKEQFGQDGPITVHCSAGVGRTGVFITLS-IVLERMRYEGVVD----------------MFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64604-1", "uniprot_id": "PTPRF_RAT", "id": "Q64604-1", "name": "Receptor-type tyrosine-protein phosphatase F", "aln": "---MAPEPAPGRRMVPLVPALVMLGLMAGAHGDSKPVFVKVPEDQIGLSGGVASFVCQATGEPKPRITWMKKGKKVS--SQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLG-EINTSAKLSVLEEDQLPSGFPTIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPASSNGRIKQLRSG------ALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPP-SSQEVMPGGNVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVMRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNTEPVSFYGIQYRAAGTDGPFQEVDGVASTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPLSAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAKAESDTRIQLSWLLPPQ--ERIIKYELVYWAAEDEGQQHKVTFDPTSSYTLEDLKPDTLYHFQLAARSDLGVGVFTPTVEACTAQSTPSAPPQKVTCVSTGSTTVRVSWVPPPADSRNGIITQYSVAYEAVDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVSWKLPVPNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLAEAQ---------ETTISGLTPETTYSITVAAYTTKGDGARSKPKVVTTTGAVPGRPTMMVSTTAMH---TALLQWHPPKELPGELLGYRLQYRRADEARPNTIDFGKDDQHFTVTGLHKGATYIFRLAAKNRAGPGEEFEKEITTPEDAPSGFPQNLRVTGLTTSTTELAWDPPVLAERNGRITNYTVVYR-DINSQHELQNVTGDVHLTLLGLKPDTTYDIKVRAHTSKGAGPLSPSIQSRTMPMEQ-VFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLI--------ADLQPNTEYSFVLMNRGTS-AGGLQHLVSIRTAPDLLPQKPLPASAFIEDG-RFSLSMPQVQDPS----------------------------LVRWFYIVVVPIDRVG----------------------GNLLAPRWSTPE---------ELELDELLEAIEQGEEKQ-------------------------------RRRRRQAERLKPYVAAQVD--ELPETFTLGDKKNYRGFYNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTP----------------------AQQQEEPEMLWVTGPVLAVILIILIVIAILLFKRKRTHSPSSKDEQSIG---LKDSLLAHS--SDPVEMRRLNYQTPG-----------MRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNSEVNKPKNRYANVIAYDHSRVLLTSIDG--VPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQR---IATVVMMTRLEEKSRVKCDQYWPARGTETYGLIQVTLVDTVELATYTMRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAMCGHTEVLARNLYAHIQKLGQVPPGESVTAMELEFKLLAGSKARASRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIG--------QVHKTKEQFGQDGPITVHCSAGVGRTGVFITLS-IVLERMRYEGVVD----------------MFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10586-1", "uniprot_id": "PTPRF_HUMAN", "id": "P10586-1", "name": "Receptor-type tyrosine-protein phosphatase F", "aln": "---MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVS--SQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLG-EINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSG------ALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPP-SSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQ--ERIIMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMN---TALLQWHPPKELPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFR-DINSQQELQNITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQ-VFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLI--------ADLQPNTEYSFVLMNRGSS-AGGLQHLVSIRTAPDLLPHKPLPASAYIEDG-RFDLSMPHVQDPS----------------------------LVRWFYIVVVPIDRVG----------------------GSMLTPRWSTPE---------ELELDELLEAIEQGGEEQ-------------------------------RRRRRQAERLKPYVAAQLD--VLPETFTLGDKKNYRGFYNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTP----------------------AQQQEEPEMLWVTGPVLAVILIILIVIAILLFKRKRTHSPSSKDEQSIG---LKDSLLAHS--SDPVEMRRLNYQTPG-----------MRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDG--VPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQR---TATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIG--------QVHKTKEQFGQDGPITVHCSAGVGRTGVFITLS-IVLERMRYEGVVD----------------MFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TXQ6-1", "uniprot_id": "A0AB32TXQ6_DANRE", "id": "A0AB32TXQ6-1", "name": "Receptor-type tyrosine-protein phosphatase F", "aln": "---MVPQTRQGSARHGATSLLLLLCLAVPIHADSMPSFVKTPEDQTGISGGVASFVCQAVGEPKPRITWMKKGKKVS--SQRFEVIEFDDGSGSVLRIQPLRTHRDEAIYECTATNSVG-EINTSAKLTVLEEDQIPHGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDINSSNGRIKQLRSGGTPIRGALQIENSEESDQGKYECVAVNSAGTRYSAPANLYVRVRRVPPRFSIPP-TNHEVMPGGSVNLTCVAVGAPMPYVKWMKGEQELTKEEEMPIGRNVLELTNIRQSGNYTCVAISSLGMIDTTAQITVKALPRPPASLIVTETTATSVTLTWDSGNPEPVSYYVIQYRSKISDNGFQEVDGVASTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSGMVETRTSEQAPSSPPLRVQARMLSATTMLVQWEPPEEPNGQIRGYRVYYTSDLHFPLSTWQKHNTEDSSLTTISGLVPDITYGLRVLAFTSVGDGPPSDILQVKTQQGVPAQPTGFEAEAELDTRIMLSWLWPVQ--DQITKYELTYWEADSDNK-HHVIFDPAGSYAIDSLKPDTLYKFSLAARSEMGLGVYTQPIEARTAQSAPSAPPQEVHLISLSSSSIKVSWVAPPAASRHGSIVRYSLAYQAVSGEDQERHEVKDIPADVSSYVLEGLEKWTEYTVWVKAHTDVGPGPESGSTRIRTQEDVPGAPPRRVEVDNINSTALRVSWKPPLQQKQHGHIRGYQVVYSRLENGEPRGQPIILDVALPEAQ---------EAVISGLLPETTYSVTVAAYTTKGDGARSKAKVVTTTGAVPGKPTMIISTTIGN---TALIQWQPPKEMVGELMGYRLRYKREEEDIYTVRDFRRTDDHFTVTGLHKGATYIFKLCAKNRAGNGEEYSKEISTPEDVPSSYPQNLKVVGLTTTTTKLAWDPPPLPERNGKIVRYVVVYR-DINSHQNQTNGTADTEMTIQGLKPDTTYDIRVRAFTGKGGGPISPSIQSRTMSTSMPEFTKNFGVKAVMKTSVLLTWEVPETYKSQVPFKILYNQQSVEVQGDLKRKLI--------TRLQPDTDYSFVLMSRGNS-AGGLQQQVSIRTAPDLFTTKPAHQKLDPEEGGKLAITLPEVHNSA----------------------------LVRWFYIVVVPVTPS--------------------------TLRHWENPE---------DIDLDELMGNN-RDAAVR-------------------------------RRRRQTQDFLRPYIAAKLE--SLPERFVLGDEKTYSNYYNKPLPGQQQYRTFILAALKD--RDSTFTVSPFSEPMMVKLHSG--------------------MSRHVEDPEMLWVMGPVLAVVLIIIIVIAILLFKRKRT-SPSAKDEHSAG---VKDHLLAHS--SDPVEMRRLNYQTQGSSAFNCPSTSRMREHPPVSVCALADHIERLRANDSLRFSQEYESVDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVVLTPVDG--VPGSDYINGNYIDGYRKQNAYIATQGPLPETLSDFWRMVWEQR---TSTIVMMTRLEEKSRVKCDQYWPSRGTETYGMIQVSMLDTVELATYSVRTFALYKNGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKSVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARSLYTHIQKLTQAPPGDTVTAMELEFKKLANSKAHTSRFISASLPCNKFKNRLVNIMPFESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLSETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIG--------QVHKTKEQFGQDGPITVHCSAGVGRTGVFITLS-IVLERMRYEGVVD----------------MFQTIKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT-----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P16621-1", "uniprot_id": "LAR_DROME", "id": "P16621-1", "name": "Tyrosine-protein phosphatase Lar", "aln": "MGLQMTAARPIAALSLLVLSLLTWTHPTIVDAAHPPEIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKVSGTQSRYTVLEQP-GGISILRIEPVRAGRDDAPYECVAENGVGDAVSADATLTIYEGDKTPAGFPVITQGPGTRVIEVGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPR---YSLKDG------FLQIENSREEDQGKYECVAENSMGTEHSKATNLYVKVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHVKWMKGSEDLTPENEMPIGRNVLQLINIQESANYTCIAASTLGQIDSVSVVKVQSLPTAPTDVQISEVTATSVRLEWSYKGPEDLQYYVIQYKPKNANQAFSEISGIITMYYVVRALSPYTEYEFYVIAVNNIGRGPPSAPATCTTGETKMESAPRNVQVRTLSSSTMVITWEPPETPNGQVTGYKVYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQQGVPSQPSNFRATDIGETAVTLQWTKPTHSSENIVHYEL-YWNDTYANQAHHKRISNSEAYTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGAPPRNITAIATSSTTISLSWLPPPVERSNGRIIYYKVFFVEVGREDDE---ATTMTLNMTSIVLDELKRWTEYKIWVLAGTSVGDGPRSHPIILRTQEDVP-GDPQDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHIHAQELRDEGKGFLNEPFKFDVVDTL---------EFNVTGLQPDTKYSIQVAALTRKGDGDRSAAIVVKTPGGVPVRPTVSLKIMEREPIVSIELEWERPAQTYGELRGYRLRWGVKDQALKEEMLSGPQMTKKRFDNLERGVEYEFRVAGSNHIGIGQETVKIFQTPEGTPGGPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFHKKIDHGLGSERNMTLRKAVFTNLEENTEYIFRVRAYTKQGAGPFSDKLIVETERDMG-RAPMSLQAEATSEQTAEIWWEPVTSRGKLLGYKIFYTMTAVEDLDDWQTKTVGLTESADLVNLEKFAQYAVAIAARFKNGLGRLSEKVTVRIKPEDVPLN-LRAHDVSTHSMTLSWSPPIRLTPVNYKISFDAMKVFVDSQGFSQTQIVPKREIILKHYVKTHTINELSPFTTYNVNVSAIPSDYSYRPPTKITVTTQMAAPQPMVKPDFYGVVNGEEILVILPQASEEYGPISHYYLVVVPEDKSNLHKIPDQFLTDDLLPGRNKPERPNAPYIAAKFPQRSIPFTFHLGSGDDYHNFTNRKLEREKRYRIFVRAVVDTP-QKHLYTSSPFSEFLSLDMREAPPGERPHRPDPNWPAEPEVSVNRNKDEPEILWVVLPLMVSTFIVSTALIVLCVVKRRRQPCKTPDQAAVTRPLMAADLGAGPTPSDPVDMRRLNFQTPG-----------MISHPPIPISEFANHIERLKSNDNQKFSQEYESIEPGQQFTWDNSNLEHNKSKNRYANVTAYDHSRVQLPAVEG--VVGSDYINANYCDGYRKHNAYVATQGPLQETFVDFWRMCWELK---TATIVMMTRLEERTRIKCDQYWPTRGTETYGQIFVTITETQELATYSIRTFQLCRQGFNDRREIKQLQFTAWPDHGVPDHPAPFLQFLRRCRALTPPESGPVIVHCSAGVGRTGCYIVIDSMLERMKHEKIIDIYGHVTCLRAQRNYMVQTEDQYIFIHDAILEAIICGVTEVPARNLHTHLQKLLITEPGETISGMEVEFKKLSNVKMDSSKFVTANLPCNKHKNRLVHILPYESSRVYLTPIHGIEGSDYVNASFIDGYRYRSAYIAAQGPVQDAAEDFWRMLWEHNSTIVVMLTKLKEMGREKCFQYWPHERSVRYQYYVVDPIAEYNMPQYKLREFKVTDARDGSSRTVRQFQFIDWPEQGVPKSGEGFIDFIG--------QVHKTKEQFGQDGPITVHCSAGVGRSGVFITLS-IVLERMQYEGVLD----------------VFQTVRILRSQRPAMVQTEDQYHFCYRAALEYLGSFDNYTN-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25044-1", "uniprot_id": "PTP1_YEAST", "id": "P25044-1", "name": "Tyrosine-protein phosphatase 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAPWYIRQRD-------------------------------------------------------------TDLLGKFKFIQNQEDGRLREATNGTVN-SRWSLGVSIEPRNDARNRYVNIMPYERNRVHLKTLSGNDYINASYVKVNVPGQSIEPGYYIATQGPTRKTWDQFWQMCYHNCPLDNIVIVMVTPLVEYNREKCYQYWPRGGVD----------DTVRIAS-------------------------KWESPGGANDMTQFPSDLK---------------------------------------------------------------------------------------------------------------------------------------------------------------------IEFVNVHKVKDYYTVTD------------------------------------------------------------------IKLTPTDPLVGPVKTVHHFYFDLWKDMNKP---EEVVPIME--------LCAHSHSLNSRGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITERSRHSDRATEEYTRDLIEQIVLQLRSQRMKMVQTKDQFLFIY-HAAKYLNSLSVNQ------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40048-1", "uniprot_id": "PTP3_YEAST", "id": "P40048-1", "name": "Tyrosine-protein phosphatase 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKDSVDCPSILPTDRTSVLSETSTLVGSSSHVYSRHAPMNSYHNSMNSNIYHSPKASSPLVSYKTSSP----------------------VLLKRATAPVLPSFKPKEQRYNKPQGCSLITAVELG-------------------------------------------KIIETLPDEKVLLLDVRPFTEHAKSIITNSIHVCLPSTLLRRKNFTFSKLLDNLTPSEQSVLKSKLAIDNLRIIIYDSTANQTES--------------------------------------------------------------SVSLPCYGIASKLIEFDTNVKKTVSILMCGFPQFKILFPDHINTNTFNSDCISSAEPK----------SPKTNLMNSLHNTAPHMTATTPLSSPQMNLKLKVPDDSRSDHSNFSSSPSPRN---------------------------VLSDSPMSSSSPISALFKFQLPAPQTNINQMFKFSQNEEIMGLETYLSAVNIKEEHERWYNNDSAKKSLQN-------------------------------FQFPKNQNSLEKDTNKDKLGFQIRYENLSKNYEKEVIDSVIPEWFQHLMSIPKIELVSQFQKLDFLEK-------------------------------------------------------------------RRLNHSVSFRKKENSFILEKPSSYPEQLTSTSSSTIMPPKFPDVN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KVQKRSHSQPIFTQYSKYKSMLSLESDSDSES--------------------------------------------DDVIISSGVELGAKNRYKDIFPYEHSRVILKKGLQSSKGIKHSHSTSDGGILDNYINANYLSLPRFSVEQ----NSSFQTTTTTTRRVR---YIATQAPMPSTVHDFYTCILNNG---VPLVLSLTNDFENGIEKCYRYWQEGNYNGIHVKLLEKKILKMPSTTSMRKNTMGTQNS------------SLYSAGVQGNSSNYSTDNDN-------------------------------------------------------------------------------------------------------------------------------------------------------------------DNDNNNNNNNNSNIAVTAAACDDDDDD--------------------------------------------------DDDAILIRKILLTYHDQEKPYELLQIQVKNWPDLGTLLNPISILQAINVKNHIIDTLFARNYYQNDQLPTILVHCSAGCGRTGTLCTIDSILSNFEMFEMLQKEFVKLKYPAKLFDP--ISWTINIFRKQRISMVQNINQFIFIYDCLLFYFRLRLDDITERTDGDGSNKDNISLSALIEQIEKLEILQTFVDDKLKELPQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :: . : : . .. . * : : .:. .:.: . . . *:***.* .* :*: . :: :* * ** :** . : :: . * : . : . .. .: :: * : :: . * : . .: : :. .: .* ****** **:*.: ::. :: : :: : . : : :*.** ***. :*: : * *: ", "identical_positions": 36, "similar_positions": 85, "identity": "1.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020107-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0V2N1-1", "uniprot_id": "PTPRS_MOUSE", "id": "B0V2N1-1", "name": "Receptor-type tyrosine-protein phosphatase S", "aln": "---MAPTWSPSVVSVVGPVGLFLVLLARGCLAEEPPRFIREPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVN-SQRFETIDFDESSGAVLRIQPLRTPRDENVYECVAQNSVGE-ITIHAKLTVLREDQLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLR---------SGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVR----VRRVAPRFSILP-MSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPVVTENTATSITVTWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSETSIGLSWSAPRQ--ESVIKYELLFREGDRGREVGRTFDPTTAFVVEDLKPNTEYAFRLAARSPQGLGAFTAVVRQRTLQAKPSAPPQDVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPDPKEVNNIPPTTTQILLEALEKWTEYRVTAVAYTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDIMLADAQ---------EMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQT---PEGSLLARWEPPADAAED-PVLGYRLQFGREDAAP-ATLELAAWERRFAAP-AHKGATYVFRLAARGRAGLGEEAAAALSIPEDAPRGFPQILGAAGNVSAGSVLLRWLPPVPAERNGAIIKYTVSVREAGAPGPATETELAAAAQPGAETALTLRGLRPETAYELRVRAHTRRGPGPFSPPLRYR-LARDPVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYNG-LTLDVDGRTTKKL-------ITHLKPHTFYNFVLTNRGSS-LGGLQQTVTARTAFN----------------MLSGKPSVAPKP--------------DNDGFIVVYLPDGQ----------------SPVTVQNYFIVMVP----LRKSRGGQFPVLLGSPE---------DMDLEELIQD--ISRLQRRSLRHSRQLEVPR-----------------------------PYIAARF--SILPAVFHPGNQKQYGGFDNRGLEPGHRYVLFVLAVLQKN-EPTFAASPFSDPFQLDNPDPQPIV--------------------DGEEGLIWVIGPVLAVVFIICIVIAILLYKN-KPDS-KRKDSEPRTKCLLNNADLAPHHPKDPVEMRRINFQTPG----------------MLSHPPIPITDMAEHMERLKANDSLKLSQEYESIDPGQQFTWEHSNLEANKPKNRYANVIAYDHSRVILQPLEG--IMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRMVWE---QRSATVVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSLHKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKTEKTVDVYGHVTLMRSQRNYMVQTEDQYGFIHEALLEAVGCGNTEVPARSLYTYIQKLAQVEPGEHVTGMELEFKRLASSKAHTSRFITASLPCNKFKNRLVNILPYESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGAPKSGEGFIDFIGQVHKTKEQFGQD--------GPISVHCSAGVGRTGVFITLS-IVLERMRYEGVVD----------------IFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLGSFDHYAT-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64605-1", "uniprot_id": "PTPRS_RAT", "id": "Q64605-1", "name": "Receptor-type tyrosine-protein phosphatase S", "aln": "---MAPTWRPSVVSVVGPVGLFLVLLARGCLAEEPPRFIREPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVN-SQRFETIDFDESSGAVLRIQPLRTPRDENVYECVAQNSVGE-ITVHAKLTVLREDQLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLR---------SGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVR----VRRVAPRFSILP-MSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPVVTENTATSITVTWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSETSIGLSWSAPRQ--ESVIKYELLFREGDRGREVGRTFDPTTAFVVEDLKPNTEYAFRLAARSPQGLGAFTAVVRQRTLQAKPSAPPQDVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPDPKEVNNIPPTTTQILLEALEKWTEYRVTAVAYTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDIMLADAQ---------EMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQT---PEGSLLARWEPPADAAED-PVLGYRLQFGREDAAP-ATLELAAWERRFAAP-AHKGATYVFRLAARGRAGLGEEASAALSIPEDAPRGFPQILGAAGNVSAGSVILRWLPPVPAERNGAIIKYTVSVREAGAPGPATETELAAAAQPGAETALTLQGLRPETAYELRVRAHTRRGPGPFSPPLRYR-LARDPVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYNG-LTLDVDGRTTKKL-------ITHLKPHTFYNFVLTNRGSS-LGGLQQTVTARTAFN----------------MLSGKPSVAPKP--------------DNDGSIVVYLPDGQ----------------SPVTVQNYFIVMVP----LRKSRGGQFPILLGSPE---------DMDLEELIQD--LSRLQRRSLRHSRQLEVPR-----------------------------PYIAARF--SILPAVFHPGNQKQYGGFDNRGLEPGHRYVLFVLAVLQKN-EPTFAASPFSDPFQLDNPDPQPIV--------------------DGEEGLIWVIGPVLAVVFIICIVIAILLYKN-KPDS-KRKDSEPRTKCLLNNADLAPHHPKDPVEMRRINFQTPG----------------MLSHPPIPITDMAEHMERLKANDSLKLSQEYESIDPGQQFTWEHSNLEANKPKNRYANVIAYDHSRVILQPLEG--IMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRMVWE---QRSATVVMMTRLEEKSRVKCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSLHKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPVVVHCSAGVGRTGCFIVIDAMLERIRTEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYTYIQKLAQVEPGEHVTGMELEFKRLASSKAHTSRFITASLPCNKFKNRLVNILPYESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGAPKSGEGFIDFIGQVHKTKEQFGQD--------GPISVHCSAGVGRTGVFITLS-IVLERMRYEGVVD----------------IFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLGSFDHYAT-----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13332-1", "uniprot_id": "PTPRS_HUMAN", "id": "Q13332-1", "name": "Receptor-type tyrosine-protein phosphatase S", "aln": "---MAPTWGPGMVSVVGPMGLLVVLLVGGCAAEEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVN-SQRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGE-ITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILP-MSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQ--ESIIKYELLFREGDHGREVGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQT---PEGSLLARWEPPAGTAED-QVLGYRLQFGREDSTPLATLEFPPSEDRYTASGVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLLRWLPPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVRAHTRRGPGPFSPPVRYRTFLRDQVSPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYNG-LTLDVDGRTTKKL-------ITHLKPHTFYNFVLTNRGSS-LGGLQQTVTAWTAFN----------------LLNGKPSVAPKP--------------DADGFIMVYLPDGQ----------------SPVPVQSYFIVMVP----LRKSRGGQFLTPLGSPE---------DMDLEELIQD--ISRLQRRSLRHSRQLEVPR-----------------------------PYIAARF--SVLPPTFHPGDQKQYGGFDNRGLEPGHRYVLFVLAVLQKS-EPTFAASPFSDPFQLDNPDPQPIV--------------------DGEEGLIWVIGPVLAVVFIICIVIAILLYKN-KPDS-KRKDSEPRTKCLLNNADLAPHHPKDPVEMRRINFQTPDSGLRSPLREPGFHFESMLSHPPIPIADMAEHTERLKANDSLKLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEG--IMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWE---QRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQVEPGEHVTGMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQD--------GPISVHCSAGVGRTGVFITLS-IVLERMRYEGVVD----------------IFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYAT-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TAP8-1", "uniprot_id": "A0AB32TAP8_DANRE", "id": "A0AB32TAP8-1", "name": "protein-tyrosine-phosphatase", "aln": "---MMPTGHLPILLSLS--ALLLSPLLTGSLALSSPRFTKVPVDMIGVSGGVVSFVCQATGDPKPKVTWNKKGKRVN-SQRIETIEFDEGAGAVLRIQPLRAPRDENVYECQAENSEGE-INVQAKLSIIREDLLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPIDPNTSNGRIKQLR---------SGALQIENTEETDQGKYECVASNVEGVRYSSPANLYVRELREVRRVPPRFSILP-TSQEIMPGGSVNITCVAVGSPMPYVKWMLNSEDLTPEDEMPVGRNVLELNSVRESANYTCVAMSSLGIIETVAQITVKSLPKPPGTPVVTETTATSITITWDSGNPEPVSHYIIQYRAKSPESKFETVDSITTTRYSIGGLSPNTDYEIRVSAFNTIGQGPPSEPVEARTGEQAPASPPRNIQARIISQNTVLVRWDEPDEPNGQIKGYRVYYTMDPTLPMSMWQIHNVQDSVLTTIQSLVTSETYTIRVLAFTSVGDGPFSDPIHVKVLQGVPGQPTNFQVGEVSDTGVELTWEPAFEK-EGIISYELHYKEGKDGPLGKKKFAPTSSFVVDGLRPNTEYFFSLAAVSSKGIGAFTNDLAQTTSQAKPSAPPQDIKCSSSSSTVLMVSWRPPPAESQNGELAGYIVRYAVVGAG-AEVSTEHVEAPTSDQILLQRLEKWTMYRVTVAASTSVGSGPESEPLLCRTDEDVPGAPPRRVEVEVLNSTAIKVMWRSLLPGKQHGQIRGYQVHYVRVENGESRGLPLIKDVMLADAQWEMDDTAEYEMVIGGLQPDTTYSITVAAYTTKGDGARSKPKLVLTKGAVPGPPFLSVNQN---SESTAIIRWQPPDYVAPGLEVQGYRLQFGRKDVNPLATLEFGPQELEYSISNIHRGATYIFKVSAKSKSGFGEEATQELRVPEEVPRGYPQITEGS-NITCCSVQFSWLPPVLAERNGAITEYTLSYQEAGTISGPKELRLPAD-----ENSYILNSLRPNAVYDVKIRAHTSVGPGPYSPPIQYRTVAYEADVPRNFTVKLVTKTTVLLSWKFYDSR-FPYKCTIEYHR-QKSDIDARMTKTL-------ITNLRPNTTYEFRISCQDSS-DGGPKHKLVARTAPH----------------IQIRKPELDLKR--------------ESESTLTIVFPPLE----------------TKDLIKAIYVVVVP----LKKGKGP--MRHIKSPD---------ELDLEELLGERRLGLHHSGTTRQLKQVDGKR-----------------------------PYIAASFKPSSMPPSFTLGNQMMYGSFENRALDRGQEYVLFILAELNTTGVKAFVSSPYTDPIMAPDLDPQPLE--------------------SGGDGLIWVVGPVLAVVFIICIVIAILLYKNSKPDSSKRKESEPRTKCLLNNADITPHHPTDPVEMRRINFQTPDSGLSSPVSEAGFDYESMMNHPPIPISELAEHTELLKANDNLKLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVILAPIEG--ITGSDYINSNYIDGYRKQNAYIATQGPLPETFGDFWRMVWE---QRAATVVMMTRLEEKSRIKCDQYWPSRGTETYGMIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIIAHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACGNTEVAARSLFSYIQKLAQVEAGEHVSGMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPYETTRVCLQPIRGLEGSDYINSSFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQD--------GPISVHCSAGVGRTGVFITLS-IVLERMRYEGVVD----------------IFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYAT-----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P16621-1", "uniprot_id": "LAR_DROME", "id": "P16621-1", "name": "Tyrosine-protein phosphatase Lar", "aln": "MGLQMTAARPIAALSLLVLSLLTWTHPTIVDAAHPPEIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKVSGTQSRYTVLEQPGGISILRIEPVRAGRDDAPYECVAENGVGDAVSADATLTIYEGDKTPAGFPVITQGPGTRVIEVGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPR---YSLK---------DGFLQIENSREEDQGKYECVAENSMGTEHSKATNLYVK----VRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHVKWMKGSEDLTPENEMPIGRNVLQLINIQESANYTCIAASTLGQIDSVSVVKVQSLPTAPTDVQISEVTATSVRLEWSYKGPEDLQYYVIQYKPKNANQAFSEISGIITMYYVVRALSPYTEYEFYVIAVNNIGRGPPSAPATCTTGETKMESAPRNVQVRTLSSSTMVITWEPPETPNGQVTGYKVYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQQGVPSQPSNFRATDIGETAVTLQWTKPTHSSENIVHYELYWNDTYANQAHHKRISNSEAYTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGAPPRNITAIATSSTTISLSWLPPPVERSNGRIIYYKVFFVEVGREDDEATTMTLN---MTSIVLDELKRWTEYKIWVLAGTSVGDGPRSHPIILRTQEDVPGDP-QDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHIHAQELRDEGKGFLNEPFKFDVVDTL---------EFNVTGLQPDTKYSIQVAALTRKGDGDRSAAIVVKTPGGVPVRPTVSLKIMEREPIVSIELEWERPAQTYGE--LRGYRLRWGVKDQALKEEMLSGPQMTKKRFDNLERGVEYEFRVAGSNHIGIGQETVKIFQTPEGTPGGPPSNITIR-FQTPDVLCVTWDPPTREHRNGIITRYDVQFHKKIDHGLGSERNMTLR-------KAVFTNLEENTEYIFRVRAYTKQGAGPFSDKLIVETERDMGRAPMSLQAEATSEQTAEIWWEPVTSRGKLLGYKIFYTMTAVEDLDDWQTKTVGLTESADLVNLEKFAQYAVAIAARFKNGLGRLSEKVTVRIKPEDVPLNLRAHDVSTHSMTLSWSPPIRLTPVNYKISFDAMKVFVDSQGFSQTQIVPKREIILKHYVKTHTINELSPFTTYNVNVSAIPSDYSYRPPTKITVTTQMAAPQPMVKPDFYGVVNGEEILVILPQASEEYGPISHYYLVVVPEDKSNLHKIPDQFLTDDLLPGRNKPERPNAPYIAAKFPQRSIPFTFHLGSGDDYHNFTNRKLEREKRYRIFVRAVVDTPQKHLYTSSPFSEFLSLDMREAPPGERPHRPDPNWPAEPEVSVNRNKDEPEILWVVLPLMVSTFIVSTALIVLCVVKRRRQPCKTPDQAAVTRPLMAADLGAGPTPSDPVDMRRLNFQTPG----------------MISHPPIPISEFANHIERLKSNDNQKFSQEYESIEPGQQFTWDNSNLEHNKSKNRYANVTAYDHSRVQLPAVEG--VVGSDYINANYCDGYRKHNAYVATQGPLQETFVDFWRMCWE---LKTATIVMMTRLEERTRIKCDQYWPTRGTETYGQIFVTITETQELATYSIRTFQLCRQGFNDRREIKQLQFTAWPDHGVPDHPAPFLQFLRRCRALTPPESGPVIVHCSAGVGRTGCYIVIDSMLERMKHEKIIDIYGHVTCLRAQRNYMVQTEDQYIFIHDAILEAIICGVTEVPARNLHTHLQKLLITEPGETISGMEVEFKKLSNVKMDSSKFVTANLPCNKHKNRLVHILPYESSRVYLTPIHGIEGSDYVNASFIDGYRYRSAYIAAQGPVQDAAEDFWRMLWEHNSTIVVMLTKLKEMGREKCFQYWPHERSVRYQYYVVDPIAEYNMPQYKLREFKVTDARDGSSRTVRQFQFIDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQD--------GPITVHCSAGVGRSGVFITLS-IVLERMQYEGVLD----------------VFQTVRILRSQRPAMVQTEDQYHFCYRAALEYLGSFDNYTN-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25044-1", "uniprot_id": "PTP1_YEAST", "id": "P25044-1", "name": "Tyrosine-protein phosphatase 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAPWYIRQR------------------------------DTDLLGKFKFIQNQEDGRLREATNGTVN-SRWSLGVSIEPRNDARNRYVNIMPYERNRVHLKTLSGNDYINASYVKVNVPGQSIEPGYYIATQGPTRKTWDQFWQMCYHNCPLDNIVIVMVTPLVEYNREKCYQYWPRGGVDDT---------------------------------------------------------VRIASKWESPGGANDMTQFPS---------------------------------------------------------------------------------------DLKIEFVNVHKVKDY-----------------------YTVTDIKLTPTDPLVG---------------------------------------------------------------------------------------------------PVKTVHHFYFDLWKDMNKP---EEVVPIMELCAHSHSLNSRG--------NPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITERSRHSDRATEEYTRDLIEQIVLQLRSQRMKMVQTKDQFLFIYHAA-KYLNSLSVNQ------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40048-1", "uniprot_id": "PTP3_YEAST", "id": "P40048-1", "name": "Tyrosine-protein phosphatase 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKDSVDCPSILPTDRTSVLSETSTLVGSSSHVYSRHAPMNSYHNSMNSN--------------IYHSPKASSPLVSYKTSSPVLLKRATAP------------------------------VLPSFKPKEQRYNKPQGCSLITAVELG----------------KIIETLPDEKVLLLDVRPFTEHAKSIITNSIHVCLPS---------------------------------------------------TLLRRKNFTFSKLLDNLTPSEQSVLKSKLAIDNLRIIIYDSTANQTESSVSLPCYGIASKLIEFDTNVKKTVSILMCG--------------------------------FPQFKILFPDHINTNTFNSDCISSAEPKSPKTNLMNSLHNTAPHMTATTPLSSPQMNLKLKVPDDSRSD---------------------------------------------------HSNFSSSPSPRNVLSDSPMSSSSPIS----------------------------------------ALFKFQLPAPQTNINQMFKFSQNEEIMGLETYLSAVNIKEEHERWYNNDSAKKSLQNFQFPKNQ-----------------------------------------------------------------NSLEKDTNKDKLGFQIRYENLSKNYEKEVIDSVIPEWFQHLMSIPKIELVSQFQKLDFLEKRRLNHSVSFRKKENSFILEKPSSYPEQLTSTSSS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TIMPPKFPDVNKVQKRSHSQPIFTQYSKYKSMLSLESDSDSES--------------------DDVIISSGVELGAKNRYKDIFPYEHSRVILKKGLQSSKGIKHSHSTSDGGILDNYINANYLSLPRFSVEQ----NSSFQTTTTTTRRVR---YIATQAPMPSTVHDFYTCILN---NGVPLVLSLTNDFENGIEKCYRYWQEGNYNGIHVK------------------------------------------------------LLEKKILKMPSTTSMRKNTMG----------------------------------------------------------------------------------------TQNSSLYSAGVQGNSSNYSTDNDNDNDNNNNNNNNSNIAVTAAACDDDDDDDDD-----------------------------------------------------------------------------------AILIRKILLTYHDQEKPYELLQIQVKNWPDLGTLLNPISILQAINVKNHIIDTLFARNYYQNDQLPTILVHCSAGCGRTGTLCTIDSILSNFEMFEMLQKEFVKLKYPAKLFDP--ISWTINIFRKQRISMVQNINQFIFIYDCLLFYFRLRLDDITERTDGDGSNKDNISLSALIEQIEKLEILQTFVDDKLKELPQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :. : :: . : : . .. . * : : .:. .:.: . . *:***.* .* :*: . :: :* * ** :** . : : * : . : . : : . : :: . * : . .: : : . .* ****** **:*.: ::. :: : :: : . : : :*.** ***. ::: * : . *: ", "identical_positions": 34, "similar_positions": 81, "identity": "1.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020108-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07602-1", "uniprot_id": "SAP_HUMAN", "id": "P07602-1", "name": "Prosaposin", "aln": "MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLYPQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMMHMQ---PKEICALVGFCD-EVKEMPMQTLVPAK-VASKNVIPALELVEPIK----KHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSG-------------------------------TRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61207-1", "uniprot_id": "SAP_MOUSE", "id": "Q61207-1", "name": "Prosaposin", "aln": "MYALALFASLLATALTSPVQDPKTCSGGSAVLCRDVKTAVDCGAVKHCQQMVWSKPTAKSLPCDICKTVVTEAGNLLKDNATQEEILHYLEKTCEWIHDSSLSASCKEVVDSYLPVILDMIKGEMSNPGEVCSALNLCQSLQEYLAEQN-QKQLESNKIPEVDMARVVAPFMSNIPLLLYPQDHPRSQPQPKANEDVCQDCMKLVSDVQTAVKTNSSFIQGFVDHVKEDCDRLGPGVSDICKNYVDQYSEVCVQMLMHMQDQQPKEICVLAGFCN-EVKRVPMKTLVPAT-ETIKNILPALEMMDPYE----QNLVQAHNVILCQTCQFVMNKFSELIVNNATEELLVKGLSNACALLPDPARTKCQEVVGTFGPSLLDIFIHEVNPSSLCGVIGLCAARPELVEALEQPAPAIVSALLKEPTPPKQPAQPKQSALPAHVPPQKNGGFCEVCKKLVLYLEHNLEKNSTKEEILAALEKGCSFLPDPYQKQCDDFVAEYEPLLLEILVEVMDPGFVCSKIGVCPSAYKLLLGTEKCVWGPSYWCQNMETAARCNAVDHCKRHVWN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FCT1-1", "uniprot_id": "E7FCT1_DANRE", "id": "E7FCT1-1", "name": "Prosaposin", "aln": "--MMLLTLLLVTTAVASPLLGTEQCARGPPYWCQNVKTASLCGAVQHCQQNVWNKPQMKTVPCDLCKEVLVVVEQLLKDNVTESELLGYLEKACQLIPDEGLANQCKEIVDNYFPVLMGIIQGELDDPGVVCGALGLCVSQQAALAKAQ----LTSNEIPQVDLNQRVSPFLLNIPQLLYPEE---KRETPKQKGDVCQDCVTFINDTQDEARVNSSFISTLIAQVENQCELLGPGMSDMCKEYISQYGPLVFQQLMSME-QQPKDICARAGFCPTKQKSVPMEKLLPAKSIPAVKMFPAVKVEKPVATMPAKNLVRVRDSPQCAICEYVMKEIENMIQDQTSEAEIVQAVEKVCNILPSTLTAQCKDLIETYGQAIIDLLVQEADPKTVCSFLALCSG--------------------------------VSHVPVMDKQHFAAGGFCDVCKMAVRYVDGILEQNATQSEIEEAVLKVCSFLPDAVKDECNQLIEQYEPLLVQLLLQTLDPDFVCMKLGACPEAVQRLLGLNQCSWGPAYWCKNVQTAARCNALNHCRRHVWS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * *: :*::.*: . : *: *.. *::**** ****:** * **.** *::***:** *:. . ::****.*:.*:* ****:*: : . .:: .***:**.*:**::.:*:**:. ** **.**.** * * **: : * **:**::*: . *:**: *** ****:: .: ** : ******: ::.* * .:.**:*:. :: :*:::*: ****::*:**:*:.**. : .* :* *: **:**. .*** : * :**:.*:**. . :::**::: .* :: * .:. * *::::::. ::* :: :* ::....: * **.. :*:::: *:* :::.:::.*..*. :*..: **:. . . ****:*** * *:: **:*:*:.** *: * ******. :.:*:::: :***:*:::*::.:**.*** *:*.**.* : *** ::* ***:***:* :***:***::**:****.", "identical_positions": 202, "similar_positions": 198, "identity": "35.82%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020108-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LMY4-1", "uniprot_id": "RYR1_RAT", "id": "F1LMY4-1", "name": "Ryanodine receptor 1", "aln": "MGDGG-GEGEDEVQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFILEQSLSVRALQEMLANTVEAGVE------SSQGGGHRTLLYGHAILLRHAHSRMYLSCLTTSRSMTDKLAFDVGLQEDATGEACWWTMHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTASGELQVDASFMQTLWNMNPICSCCE----EGFVTGGHVLRLFHGHMDECLTISPSDS-DDQRRLVYYEGGPVCTHARSLWRLEPLRISWSGSHLRWGQPLRIRHVTTGRYLALTEDQGLVVVDASKAHTKATSFCFRISKE-KLDVAPKRDVEGMGPPEIKYGESLCFVQHVASGLWLTYAAPDPKALRLG-VLKKKAMLHQEGHMDDALSLTRCQQEESQAARMIYSTAGLYNQFIKGLDSFSGKPRGSGPPAGSALPIEGVILSLQDLIGYFEPPSEELQHEEKQTKLRSLRNRQSLFQEEGMLSLVLNCIDRLNVYTTAAHFAEFAG-EEAAESWKEIVNLLYELLASLIRGNRTNCALFSTN--LDWLVSKLDRLEAS--SGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGSTQYGKWYFEVMVDEVAPFLTAQATHLRVGWALSEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWTGHVARPVTS--PGQHLLGPEDVVSCCLDLSVPSISFRINGCPVQGVFESFNLDGLFFPVVSFSAGIKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLHLQPIKEYRREGPRGPHLVGPSRCLSHLDFVPCPVDTIQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDNKRLHPCLVDFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLKKTKLP-KTYMMNNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVAQGWSYSAVQDIPARRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPPDQEPS-QVDSQSR---GDRARIFRAEKSYAVQSGRWYFEFEAVTTGR-ELGWARPELRPDVELGADDLAYVFNGHRGQRWHLG-SEPFGRPWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFREIEIG-DGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQFEP-VPLEHPHYEVARMDGTVDTPPCLRLTHRTWGSQNSLVEMLFLRLSLPVQFHQHFRCTAG------------------------------------------------------------------ATPLASPGLQPPAEDEARAAEPDTDYENLRRSAGGWGEAEAGKDGTAKEGTPGGAAQPGVEAQPARAENEKDATTEKN--KKRGFLFKAKKVAMMTQPPSTPALPRLPRDVVPADNRDDPEIILN-----------------------TTTYYYSVRVFAGQEPSCVWVGWVTPDYHQHDMSFDLSKVRAVTVTMGDEQGNVHSSLKCSNCYMVWGGDFVSPGQQGRISH---TDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQNVVQFDLRPGANIMPLSAAMFLSERKNPAPQCPPRLEVQMLMPVSWSRMPNHFLHVDTRRAGERLGWAVQCQEPLMMMALHIPEENSEPYIHLKRAQLDPRDLRDYRDTKFDSESSD-SDQTPQPGCYHVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTEETRAITLFPPGRSAEDGPRRHGLPGVGVTTSLRPPHHFSPPCFVVALPAAGAAEAPARLSPAIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLLVMGVFSDEDVKQILKMIEPEVFT-----------------------------------------------EEEEVEEEEEE-EEEDEEEKEEDEEEEAHEKEDEEKEEA---------EEAAEEEKEELEEGLLQMKLPESVKLQMCHLLEYFCDQELQHRVESLAAFAERYVDKLQSNQRGRYGLLMKAFTMSAAETARRTREFRSPPQEQINMLLQFKNGA--DEEDCPLPEEIREDLVNFHQDLLAHCGIQLEGEEEEPE---EESTLGSRLMSLLEKVRLVKKKEEKPEEEPAAEE-HKPQSLQELVSHTVVRWAQEDFVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISLSSVEDTMSLLECLGQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLG-----------------GGESKE-IRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLG---MQGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLLAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPALRGEGGSGLLAAIEEAIRISEDPAR------DGPGVRRDRRREHFG-EEPPEENRVHLGHAIMSFYAALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPLDDLVGIISLPLQIPTLGKDGALVQPKMSASFVPDHKASMVLFLDRVYGIENQDFLLHVLDVGFLPDMRAAASLDTATFSR-RWALALTRYLC-AVLPLITKCAPLLRGTEHRAIMVDSMLHTVYRLSRGRSLTKAQRDVIEDCLMALCRYIRPSMLQHLLRRLVFDVPILNEFAKMPLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDQELYRIAMPCLCAIAGALPPDYVDASYSSKTEKKATVDAEG--NFDPRPVETLNVIIPEKLDSFINKFAEYAHEKWAFDKIQNNWSYGENIDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTVEKAREGEEEKTEKKKTRKISQTAQT-YDPREG---YNPQPPDLSVVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGSHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAVTRHGKDMELD-----TSSIEKRFAFGFLQQLLRWMDISQEFIAHLEAVVS-SGRVEKSPHEQEIKFFAKILLPLINQYFTNHCLYFLSTPAKVLGSGGHASNKEKEMITSLFCKLAALVRHRVSLFGTDAPAVVNCLHILARSLDARTVMKSGPEIVKAGLRSFFESASEDIEKMVENLRLGKVSQARTQVKGVGQNLTYTTVALLPVLTTLFQHIAQHQFGDDVILDDVQVSCYRTLCSIYSLGTT---------RNPYVEKLRPALGECLARLAAAMPVAFLEPELNEYNACSVYTTKSPRERAILGLPNSVEEMCPDIPVLERLMAEIGGLAESGARYTEMPHVIEITLPMLCSYLPRWWERGPEAPPPALPAGAPPPCTAVTSDHLNSLLGNILRIIVNNLGIDEASWMKRLAVFAQPIVSRARPELLRSHFIPTIGRLRKRAGKVVAEEEQLR---LEAKAEAEEGELLVRDEFSVLCRDLYALYPLLIRYVDNNRSAWPRLPPSPSSSFSLPSPSELGRWLMKDHGHQLYEESFTVPLILDNAAFPLARNQSRAIGCAGVVRSGGSDQERTKK--KRRGDRYSVQTSLIVATLKKMLPIGLNMCAPTDQDLIVLAKARYALKDTDEEVREFLQNNLNLQGKVEGSPSLRWQMALYRGVPGREE-----------------DADDPEKIVRRVQEVSAVLYHLDQTEHPYKSKKAVWHKLLSKQRRRAVVACFRMTPLYNLPTHRACNMFLESYKASWILTEDHSFEDRMIDDLSKAGEQEEE---EEEVEEKKPDPLHQLVLHFSRTALTEKS-KLDEDYLYMAYADIMAKSCHLEEGGENVEEGGEEEEVEVSFE------EKEMEKQRLLYQQSRLHNRGAAEMVLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQTCRWPHKTLSQREGQEERVMKVQTSGTLVIINRQNGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDPRGLISKKDFQKAMDSQKQFTGPEIQFLLSCSEADENEMINCEEFANRFQEPARDIGFNVAVLLTNLSEHVPHDPRLRNFLELAESILDYFRPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGESEKMELFVSFCEDTIFEMQIAAQISEPEGEPEEDDDE-------GAEEAEEGAAGPDGSGSAAAAGVWTWLATAAGRTLRGLSYRSLRRRVRRLRRLTAREAATAVAVLLWAMVARAGGAGAGAAAGVLRLLWGSLFGGGLVDSAKKVTVTELLAGMPDPTGDEVHGQQPSGAGSDAEGEGQGEGEGDAAEGVGDEEVAADQAGTGGADRTVAVADGSPFRPEGAGGLGDMGDTTPVEPPTPEGSPILKRKLGVDGEEEEPQPEPEPEPEP--EPEKADTENGEKE------VPEPPPEPPKK-APPPPPPKKEEAGGAGLEEFWGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPGEDDIEGSGAGDMSGAGSGD---GSGWGSRA-SEEVEGDEDEN-MVYYFLEESTGYMEPALRCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPEDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIFGRERIAELLGMDLASLEIT-AHNERKPDPPP-GLLTWIMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PZQ0-1", "uniprot_id": "RYR1_MOUSE", "id": "E9PZQ0-1", "name": "Ryanodine receptor 1", "aln": "MGDGG-GEGEDEVQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFILEQSLSVRALQEMLANTVEAGVE------SSQGGGHRTLLYGHAILLRHAHSRMYLSCLTTSRSMTDKLAFDVGLQEDATGEACWWTMHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTASGELQVDASFMQTLWNMNPICSGCE----EGFVTGGHVLRLFHGHMDECLTISPSDS-DDQRRLVYYEGGPVCTHARSLWRLEPLRISWSGSHLRWGQPLRIRHVTTGRYLGLTEDQGLVVVDASKAHTKATSFCFRISKE-KLDVAPKRDVEGMGPPEIKYGESLCFVQHVASGLWLTYAAPDPKALRLG-VLKKKAMLHQEGHMDDALSLTRCQQEESQAARMIYSTAGLYNQFIKGLDSFSGKPRGSGPPAGSALPIEGVILSLQDLIGYFEPPSEELQHEEKQTKLRSLRNRQSLFQEEGMLSLVLNCIDRLNVYTTAAHFAEFAG-EEAAESWKEIVNLLYELLASLIRGNRTNCALFSTN--LDWLVSKLDRLEAS--SGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGSTQYGKWYFEVMVDEVAPFLTAQATHLRVGWALSEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWTGHVARPVTS--PGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFESFNLDGLFFPVVSFSAGIKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLHLQPIKEYRREGPRGPHLVGPSRCLSHLDFVPCPVDTIQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDNKRLHPCLVNFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLKKTKLP-KTYMMSNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVAQGWSYSAVQDIPARRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPPDQEPS-QVDSQSR---GDRARIFRAEKSYAVQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADDLAYVFNGHRGQRWHLG-SEPFGRPWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFRDIEIG-DGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQFEP-VPLEHPHYEVARMDGTVDTPPCLRLTHRTWGSQNSLVEMLFLRLSLPVQFHQHFRCTAG------------------------------------------------------------------ATPLASPGLQPPAEDEARAAEPDTDYENLRRSAGGWGEAEGGKDGTAKEGTPGGTAQAGVEAQPARAENEKDATTEKN--KKRGFLFKAKKVAMMTQPPSTPALPRLPRDVVPADNRDDPEIILN-----------------------TTTYYYSVRVFAGQEPSCVWVGWVTPDYHQHDMSFDLSKVRAVTVTMGDEQGNVHSSLKCSNCYMVWGGDFVSPGQQGRISH---TDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQNVVQFELGKQKNIMPLSAAMFLSERKNPAPQCPPRLEVQMLMPVSWSRMPNHFLQVDTRRAGERLGWAVQCQEPLMMMALHIPEENRCMDILELSERLDLQRFHSHTLSLYRSVCALGNNRVAHALCSHVDQAQLLHALEDARLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTPETRAITLFPPGRSAEDGPRRHGLPGVGVTTSLRPPHHFSPPCFVVALPAAGATEAPARLSPAIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLLVMGVFSDEDVKQILKMIEPEVFR-----------------------------------------------EEEEVEEEGEE-EEEDEEEKEEDEEEEAHEKEDEEKEEA---------EDAAEEEKEELEEGLLQMKLPESVKLQMCHLLEYFCDQELQHRVESLAAFAECYVDKMQGNQRGRYGLLMKAFTMSAAETARRTREFRSPPQEQINMLLHFKNGA--DEEECPLPEEIRQELVNFHQDLLAHCGIQLEGEEEEPE---EESTLGSRLMSLLEKVKLVKKTEEKPEEEPAPEE-HKPQSLQELVSHTVVRWAQEDFVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISVSSVEDTMSLLECLGQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLG-----------------GGESKE-IRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLG---MQGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLLAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPALRGEGGSGLLAAIEEAIRISEDPAR------DGPGVRRDRRREHFG-EEPPEENRVHLGHAIMSFYAALIDLLGRCAPETHLIQAGKGEALRIRAILRSLVPLDDLVGIISLPLQIPTLGKDGALVQPKMSASFVPDHKASMVLFLDRVYGIENQDFLLHVLDVGFLPDMRAAASLDTATFSTTEMALALNRYLCLAVLPLITKCAPLFAGTEHRAIMVDSMLHTVYRLSRGRSLTKAQRDVIEDCLMALCRYIRPSMLQHLLRRLVFDVPILNEFAKMPLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDQELYRIAMPCLCAIAGALPPDYVDASYSSKTEKKATVDAEG--NFDPRPVETLNVIIPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENIDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTVEKAREGEEEKTEKKKTRKISQTAQT-YDPREG---YNPQPPDLSVVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGSHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAVTRGLKDMELD-----TSSIEKRFAFGFLQQLLRWMDISQEFIAHLEAVVS-SGRVEKSPHEQEIKFFAKILLPLINQYFTNHCLYFLSTPAKVLGSGGHASNKEKEMITSLFCKLAALVRHRVSLFGTDAPAVVNCLHILARSLDARTVMKSGPEIVKAGLRSFFESASEDIEKMVENLRLGKVSQARTQVKGVGQNLTYTTVALLPVLTTLFQHIAQHQFGDDVILDDVQVSCYRTLCSIYSLGTT---------RNPYVEKLRPALGECLARLAAAMPVAFLEPELNEYNACSVYTTKSPRERAILGLPNSVEEMCPDIPVLERLMAEIGGLAESGARYTEMPHVIEITLPMLCSYLPRWWERGPEAPPPALPAGAPPPCTAVTSDHLNSLLGNILRIIVNNLGIDEASWMKRLAVFAQPIVSRARPELLRSHFIPTIGRLRKRAGKVVAEEEQLR---LEAKAEAEEGELLVRDEFSVLCRDLYALYPLLIRYVDNNRAHWLTEP-NPNAEELFRMVGEIFIYWSKSHNFKREEQNFVVQNEINNMSFLTADNKS-KMAKAGDVQSGGSDQERTKK--KRRGDRYSVQTSLIVATLKKMLPIGLNMCAPTDQDLIVLAKARYALKDTDEEVREFLQNNLNLQGKVEGSPSLRWQMALYRGVPGREE-----------------DADDPEKIVRRVQEVSAVLYHLDQTEHPYKSKKAVWHKLLSKQRRRAVVACFRMTPLYNLPTHRACNMFLESYKASWILTEDHSFEDRMIDDLSKAGEQEEE---EEEVEEKKPDPLHQLVLHFSRTALTEKS-KLDEDYLYMAYADIMAKSCHLEEGGENGEEGGEEEEVEVSFE------EKEMEKQRLLYQQSRLHNRGAAEMVLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQTCSVLDLNAFERQNKAEGLGMVNEDG--TVINRQNGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDPRGLISKKDFQKAMDSQKQFTGPEIQFLLSCSEADENEMINCEEFANRFQEPARDIGFNVAVLLTNLSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGESEKMEMFVSFCEDTIFEMQIAAQISEPEGEPEEDEDE-------GAEEAEEGAAGSDGSGSAAAAGVWVWLAATAGRTLRGLSYRSLRRRVRRLRRLTAREAATAVAALLWALVTRAGGAGAGAAAGALRLLWGSLFGGGLVDSAKKVTVTELLAGMPDPTGDEVHGQQPSGAGSDAEGEGEGEGEGDAADGAGDEEAAADQAGTGGADGAVAVADGSPFRPEGAGGLGDMGDTTPVEPPTPEGSPILKRKLGVDGEEEEPPPEPEPEPEP--EPEKADTENGEKE------VPEPPPEPPKK-TPPPPPPKKEEAGGAGLEEFWGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPGEDDIEGSGAGDMSGAGSGD---GSGWGSRA-GEEVEGDEDEN-MVYYFLEESTGYMEPALRCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPEDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIFGRERIAELLGMDLASLEIT-AHNERKPDPPP-GLLTWIMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21817-1", "uniprot_id": "RYR1_HUMAN", "id": "P21817-1", "name": "Ryanodine receptor 1", "aln": "MGD---AEGEDEVQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFVLEQSLSVRALQEMLANTVEAGVE------SSQGGGHRTLLYGHAILLRHAHSRMYLSCLTTSRSMTDKLAFDVGLQEDATGEACWWTMHPASKQRSEGEKVRVGDDIILVSVSSERYLHLSTASGELQVDASFMQTLWNMNPICSRCE----EGFVTGGHVLRLFHGHMDECLTISPADS-DDQRRLVYYEGGAVCTHARSLWRLEPLRISWSGSHLRWGQPLRVRHVTTGQYLALTEDQGLVVVDASKAHTKATSFCFRISKE-KLDVAPKRDVEGMGPPEIKYGESLCFVQHVASGLWLTYAAPDPKALRLG-VLKKKAMLHQEGHMDDALSLTRCQQEESQAARMIHSTNGLYNQFIKSLDSFSGKPRGSGPPAGTALPIEGVILSLQDLIIYFEPPSEDLQHEEKQSKLRSLRNRQSLFQEEGMLSMVLNCIDRLNVYTTAAHFAEFAG-EEAAESWKEIVNLLYELLASLIRGNRSNCALFSTN--LDWLVSKLDRLEAS--SGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGTTQYSKWYFEVMVDEVTPFLTAQATHLRVGWALTEGYTPYPGAGEGWGGNGVGDDLYSYGFDGLHLWTGHVARPVTS--PGQHLLAPEDVISCCLDLSVPSISFRINGCPVQGVFESFNLDGLFFPVVSFSAGVKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLHLEPIKEYRREGPRGPHLVGPSRCLSHTDFVPCPVDTVQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDNKRLHPCLVDFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLKKTKLP-KTYMMSNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVGQGWSYSAVQDIPARRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPPDQEPS-QVENQSR---CDRVRIFRAEKSYTVQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADELAYVFNGHRGQRWHLG-SEPFGRPWQPGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFREIEIG-DGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKGLPQFEP-VPLEHPHYEVSRVDGTVDTPPCLRLTHRTWGSQNSLVEMLFLRLSLPVQFHQHFRCTAG------------------------------------------------------------------ATPLAPPGLQPPAEDEARAAEPDPDYENLRRSAGGWSEAENGKEGTAKEGAPGGTPQAGGEAQPARAENEKDATTEKN--KKRGFLFKAKKVAMMTQPPATPTLPRLPHDVVPADNRDDPEIILN-----------------------TTTYYYSVRVFAGQEPSCVWAGWVTPDYHQHDMSFDLSKVRVVTVTMGDEQGNVHSSLKCSNCYMVWGGDFVSPGQQGRISH---TDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQNVIQFELGKQKNIMPLSAAMFQSERKNPAPQCPPRLEMQMLMPVSWSRMPNHFLQVETRRAGERLGWAVQCQEPLTMMALHIPEENRCMDILELSERLDLQRFHSHTLRLYRAVCALGNNRVAHALCSHVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTPETRAITLFPPGRSTENGHPRHGLPGVGVTTSLRPPHHFSPPCFVAALPAAGAAEAPARLSPAIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLLVMGIFGDEDVKQILKMIEPEVFT-----------------------------------------------EEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEE---------EAAEGEKEEGLEEGLLQMKLPESVKLQMCHLLEYFCDQELQHRVESLAAFAERYVDKLQANQRSRYGLLIKAFSMTAAETARRTREFRSPPQEQINMLLQFKDGT--DEEDCPLPEEIRQDLLDFHQDLLAHCGIQLDGEEEEPE---EETTLGSRLMSLLEKVRLVKKKEEKPEEERSAEE-SKPRSLQELVSHMVVRWAQEDFVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISPSSVEDTMSLLECLGQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLG-----------------GGESKE-IRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLG---MQGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLVAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPALRGEGGSGLLAAIEEAIRISEDPAR------DGPGIRRDRRREHFG-EEPPEENRVHLGHAIMSFYAALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPLEDLVGIISLPLQIPTLGKDGALVQPKMSASFVPDHKASMVLFLDRVYGIENQDFLLHVLDVGFLPDMRAAASLDTATFSTTEMALALNRYLCLAVLPLITKCAPLFAGTEHRAIMVDSMLHTVYRLSRGRSLTKAQRDVIEDCLMSLCRYIRPSMLQHLLRRLVFDVPILNEFAKMPLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDPELYRMAMPCLCAIAGALPPDYVDASYSSKAEKKATVDAEG--NFDPRPVETLNVIIPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENIDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTIEKAREGEEEKTEKKKTRKISQSAQT-YDPREG---YNPQPPDLSAVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAVTRGLKDMELD-----SSSIEKRFAFGFLQQLLRWMDISQEFIAHLEAVVS-SGRVEKSPHEQEIKFFAKILLPLINQYFTNHCLYFLSTPAKVLGSGGHASNKEKEMITSLFCKLAALVRHRVSLFGTDAPAVVNCLHILARSLDARTVMKSGPEIVKAGLRSFFESASEDIEKMVENLRLGKVSQARTQVKGVGQNLTYTTVALLPVLTTLFQHIAQHQFGDDVILDDVQVSCYRTLCSIYSLGTT---------KNTYVEKLRPALGECLARLAAAMPVAFLEPQLNEYNACSVYTTKSPRERAILGLPNSVEEMCPDIPVLERLMADIGGLAESGARYTEMPHVIEITLPMLCSYLPRWWERGPEAPPSALPAGAPPPCTAVTSDHLNSLLGNILRIIVNNLGIDEASWMKRLAVFAQPIVSRARPELLQSHFIPTIGRLRKRAGKVVSEEEQLR---LEAKAEAQEGELLVRDEFSVLCRDLYALYPLLIRYVDNNRAQWLTEP-NPSAEELFRMVGEIFIYWSKSHNFKREEQNFVVQNEINNMSFLTADNKS-KMAKAGDIQSGGSDQERTKK--KRRGDRYSVQTSLIVATLKKMLPIGLNMCAPTDQDLITLAKTRYALKDTDEEVREFLHNNLHLQGKVEGSPSLRWQMALYRGVPGREE-----------------DADDPEKIVRRVQEVSAVLYYLDQTEHPYKSKKAVWHKLLSKQRRRAVVACFRMTPLYNLPTHRACNMFLESYKAAWILTEDHSFEDRMIDDLSKAGEQEEE---EEEVEEKKPDPLHQLVLHFSRTALTEKS-KLDEDYLYMAYADIMAKSCHLEEGGENGE---AEEEVEVSFE------EKQMEKQRLLYQQARLHTRGAAEMVLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQTCSVLDLNAFERQNKAEGLGMVNEDG--TVINRQNGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDPRGLISKKDFQKAMDSQKQFSGPEIQFLLSCSEADENEMINCEEFANRFQEPARDIGFNVAVLLTNLSEHVPHDPRLHNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGEAEKMELFVSFCEDTIFEMQIAAQISEPEGEPETDEDEGAGAAEAGAEGAEEGAAGLEGTAATAAAGATARVVAAAGRALRGLSYRSLRRRVRRLRRLTAREAATAVAALLWAAVTRAGAAGAGAAAGALGLLWGSLFGGGLVEGAKKVTVTELLAGMPDPTSDEVHGEQPAGPGGDADGEGASEGAGDAAEGAGDEEEAVHEAGPGGADGAVAVTDGGPFRPEGAGGLGDMGDTTPAEPPTPEGSPILKRKLGVDGVEEELPPEPEPEPEPELEPEKADAENGEKEE-----VPEPTPEPPKKQAPPSPPPKKEEAGG----EFWGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPGEDDMEGSAAGDVSGAGSGG---SSGWGLGA-GEEAEGDEDEN-MVYYFLEESTGYMEPALRCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPEDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIYGRERIAELLGMDLATLEIT-AHNERKPNPPP-GLLTWLMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U3K9-1", "uniprot_id": "A0AB32U3K9_DANRE", "id": "A0AB32U3K9-1", "name": "", "aln": "MAEG--AEGEEEIQFLRTDDQVVLQCTATILKEQIKLCLSCEGFGNRLCFLETTSNAQNVPPDLAICCFILEQSLSVRALQEMLANTTELNEAVDLDKWSSQGGGHRTLLYGHAILLRHTHSGMYLSCLTTSRSLTDKLAFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRVGDDIILVSVSSERYLHLSYASGDLMVDASFMQTLWNMNPVCSGCELA--EGFLTGGHVLRLFHGHMDECLTIPGAEQGDDQRRNAHYEGGAVCSHARSLWRLEPLRIGWSGSHMKWGQSFRVRHITTGRYLCLDEEKGLLIVDPEKANTKQSAFCFRASKE-KTEVAQKRDVEGMGIPEIKYGESMCFVQHVATSLWLTYASVDAKSARLG-PLKRKAILHQEGHMDDALTVARSQTAESQAARMIYNTAGLFTQFIKGLDSLSGKSKSPGPSP--SLPLDAIVLSLQDLIFYFRPPEEELEHEEKQTKLRSLRNRQNLFQEEGMITLVLDCVDRLNVYNTSAHFSEFAG-EDAAESWKEIVNLFYELLASLIRGNRANCALFCDN--LDWLVSKLDRLEAS--SGILEVLYCILIESPEVLNIIQENHIKSIIALLDKHGRNHKVLDVLCSLCVCNGVAVRSNQNLITENLLPGRDLLLQTNIINYVTSMRPNIFLGTCEGSTQYKKWYYELIVDHVESFLTAHPFHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLHSYGFDGLNLWTGRVPRQVTS--PSQHILSAEDVVSCCLDLSVPSISFRINGHPVQGMFENFNLDGLFFPVVSFSAGIKVRFLLGGRQGDFKFLPPPGYAPCYEAVLPKDRLRIEPIKEYKHDNDGVRNLLGPTQSLSHTAFTPCPVDTVQIVLPPHLERIREKLAENSHELWAVTRIEQGWTYGLFRDDNKKLHPCLVDFQSLPDPEKSYNLAMSGETLKTLLALGCHVGMGDEKAEENLKKIKLP-KTYMQCNGYKPAPLDLNHVKLTPNQNTLVERLAENGHNVWARDRVRQGWTYSIIQDIVNKRNPRLVPYILLDEKTKKTNRDTVCAAVRTLIGYGYNIEPPDQESSGHGGGNGR---SDKIRVFRAEKSYAVTQGKWYFEFEAVTVGEMRVGWARPSVHADRELGSDDLAYVFNGFKSQRWHIG-NEPFGRQWQSGDVVGCMIDLTEQNIMFTLNGEMLISDSGSEMAFKDIEIG-EGFIPVCSLGMSQVGRINLGQNVSSLRYFTICGLQEGFEPFAINMKRDITMWFSKSLPQFVP-VPTDHPHIEVSRVDGTVESAPCLKLTHRTFGSQNANTDLLFFRLSMPIEFHETFKVPVG------------------------------------------------------------------ASPLTRTLTIP--EDETLEVDPESEFELLKKSATRKEQDEKEKEPSVPKELPG----------SKESENEKDTTTEKS--KKRGFFSKAKKAAFIAPPPVVPTMPRLMEDVVPDD-RDDVEIISN-----------------------TTTYYYSVRVFAGQEPSGVWVGWVTPDYHLYDLHFDLCKVRNVTVTVGDDKGNIHDSVKRSNCYMVWGGEFSSS-QQTRISQ---EDFVIGCLVDLDTGLMTFTANGKEINTFYQVEPNTKLFPAVFCLPSSQNMLQVELGKLKNIMPISAAMFRSDCKNPVPQCPPRLDLQMLTPVIWSRMPNHFLSPETGRVSERQGWKVQCMEPLVMMALHIPEENRCIDILELSERTDLMKFHYHTLKLYGSVCALGNNRVAHALCSHVDESQLFYAIENTYLPGPIRSGYYDLLISMHLESAKRNRLMTNKEFIVPMTDETRSITLYS------DAEKAHALPGVGLTTCLRPKLHFAPTGFVGTN------ADLYTLSPMLPLQMLKDHALSMLTEAVQDGGQAIRDPVGGSVEYHFVPILKLISTLLIMGVFDDDDVKHILKLIEPSVFSSNSETPAEETGDPEQQLVCKEEGAEVKEQEEPADGGNDGELLDEGMGEEEELEEEEEEEDEEYEEEVKKEEDEHAAEKTDREKTTDGETEKETGAAEAEVREEEDVGEGLLHMKLPESVKLQMCTLLQYFCDCELRHRVEAIIAFSDKFVNQVQTNQRQRYNELMQAFTMSAAETARKTREFRSPPQEQVNMLMNFKNCP--EEEDCPVPEDVRNGLLTFHHDLLAHCGVHIEEEEQEEE---VDTSLSGRLRRLVEKVKSLRK---KPEAEPEPEEDKKPSTLQELISHTMIYWAQESFIQNPELVRLMFSLLHRQYDALGELIRALPKAYIINAVSIQDTMELLECLGQIRSLLIVQMGPEEERLMIQSIGNIMSNRVFYQHPNLMRALGMHETVMEVMVNVLG-----------------GGDSKE-IRFPRMVTNCCRFLCYFCRISRQNQRSMFDHLGYLLQNSGIGLG---MRGSTPLDVAAASCIDNNELALALQEQDLEMVVKYLAGCGLQSCPMLLSKGYPDIGWNPVGGEKYLDFLRFAVFVNGESVEENANVVVRLLIRRPECFGPALRGEGGNGLLAAIEEAIKISEDPAR------DGPTVKKDRRFPMFGGEEQHEENRVHLGNAIMSFYSALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPIEDLVGVISLSVQIPAFGKDNSIIEPKMSASFVPDHKAPMVLFLDRVYGIDNQDFLLHVLEVGFLPDMRAAASLDTAAFSTTEMALALNRYLCSAVLPLITKCAPLFAGTDHRAIMIDSMLHTIYRLSRGRSLTKAQRDVIEECLMSLCRYLRPSMLQHLLRRLVFDVPILNEYAKMPLKLLTNHYERCWKYYCLPNGWANFGVSSEEELHLTRKLFWGIFESLAHKKFDAELFKIAMPCICAIAGAIPPDYVDASYSSKTEKKASVDAEG--NFDPKPVDTTNTIIPEKLDGFINRYAEYTHDRWAFEKIQNNWTFGEVMDENAKTHPMLRPYKTFSEKDKEIYRWPIKESIKAMIAWEWTLDKARDGEDEKVEKKTARKISQTAQATYDPSHG---YSPQPIDISGMTLSRELQSMAEQLAENYHNTWGRKKKMELQAKGGGTHPLLVPYDTLTAKEKARDREKAYELLKFLQLNGYAVTRGLKDMESD-----ISSIEKRFAYGFLQKLLKWMDIAQEFIAHLEAVVS-SGRVEKSPHEQEIKFFAKILLPLINQYFKNHCLYFLSTPAKILGSGGHASNKEKEMIASIFCKMSALVRHRVFLFGTDAPAIVNCLHILARSLDARTVMKSGPEIVKAGLRLFFESAADDIEKMVENLKLGKVSKGNQPVKGVSQNINYTTTALLPVLTSLFDHIAQHQFGDDVILDDLQMSCYRIMCSIYSLGTV---------KTPHAERHRPALGECLAHLAAAMPVAYLEPHLNEYNAFSVYTTKTPRERAILGLPNQVQELCLDIPELDVLLKEIGDLAESGARYTEMPHVIEVTLPMLCNYLPRWWERGLEN----FPDLEGKLCTDVTSESLNQLLGSIMKIVVNNLGIDEASWMKRLAVFSQPIVSRAKPEMLKSHFIPTMEKLKKRTSKVVAEEEHLR---LEGKSEGDEEEGTIRDEFAVLCRDLYALYPLLIRYVDNNRARWLTFR-DPDAEELFRMVGEVFIFWSKSHNFKREEQNFVVMNEINNMSFLTADSKS-KMSKAGDSEAGGSDVERTKK--KRRGDRYSVQTSLIVAALKKMLPIGLNMCSPADQELINLAKTRYSLKDTDEEVREFLQNNLHLQGKVD-NPSMRWQMALYKEMAGKAE-----------------DADAPENVVKRVQEVSAVLYHIEVTEHPFKSKKMVWHKLLSKQRRRAVVACFRMTPLYNLPRHRASNMFLDGYKRNWIRNEGYSFEDRMIDDLSKALEEEEE---EEEEKETKPDPLHQLILHFSRTALTEKS-KLDIDHLYMAYADIMAKSCHMDEEDEGGEEENEGGEEEMSFEVRQTEMEKEMEKQRLLYQQSRLHNRGAAEMVLQMISACKGETGCMVSSTLKLGISILNGGNCEVQQKMLDYLKDKKDVGFFLSVQALMQTCSVLDLNAFERQNKAEGLGMVSEEG--TNMKLERGEKVMADDEFTCDLFRFLQLLCEGHNNDFQNYLRTQTGSTTTINVIICTVDYLLRLQESISDFYWYYSGKDIIDEPGKRNFSKAMTVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIGLLKELLDLQKDMVVMLLSLLEGNVVNGTIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVASDAFRDYVTDPRGLISKKDFQKSMDSQKQYTPSEIQFLLSCSEADENEMINYEEFASRFQEPAKDIGFNIAVLLTNLSEHVPHDTRLQNFLEQAESVLNYFRPFLGRIEIMGASRKIERIYFEISEVNRKQWEMPQVKESKRQFIFDVVNEGGESEKMELFVNFCEDTIFEMNIASQISEQDEEEKEEDDIEEAE---GGDAGDEEGGGEEGQ--PESSSAFADFIQSIMNFLGMFTFRNIRRQYRRLRKMTIKEIVVGLATFMWTILLGILHFIYSVCKGFFLLIWHTLFGGGLVEGAKNMTVTELLASMPDPTQDEVHGDLPGEPRGGEEQETGGIMDSMDAGGGEEEDEDIQEKDGGKIPG-----------IDTPGGLGDMGDTTPVEPPTPEGTPLLKRKAQPDEAGPEQPPAIE-EPPP--EPEKADIENGEKAEKEVEVKPEPIPEEPKPQRATKAKKEKKSVKGAG-FELWNELDVQRNKFMNCLSRNFYNIRFLALFLAFALNFILLFYKVSDTPPSSDEFEGSGIFEGSGLFEGS---AEDFEGSG-GEDGGDDEDEEGPVYYFLEESTGYMQPTLSFLAILHTVIAFISIIGYNCLKIPLVIFKREKELARKLEFDGLYITEQPADDDIKGQWDRLVLNTPSFPTNYWDKFVKRKVLDKYGDIYGRERIAELLGMDLASLDVSKQQTDKKPEEPDNSMLAWFTSIDIKYQIWKFGVVFTDNTFLYLVWYTVMSLLGHYNNFFFACHLLDIAMGVKTLRTILSSVTHNGKQLMMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24498-2", "uniprot_id": "RYR_DROME", "id": "Q24498-2", "name": "Ryanodine receptor", "aln": "MAEAEGGSEQDDVSFLRTEDMVTLSCTATG----ERVCLAAEGFGNRHCFLENIADKN-VPPDLSQCVFVIEQALSVRALQELVTAAGSETGK-------GTGSGHRTLLYGNAILLRHHNSDMYLACLSTS-SSNDKLSFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYLHTTKENEQSIVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHG-GDECLTIPSTWGREAGQNIVIYEGGVVMAQARSLWRLELARTKWTGGFINWYHPMRIRHITTGRYLGVNDSNELILVKKEEASIATTTFCLRQEKDDEKKVLEDKDLEVIGSPIIKYGDTTVIVQHCETSLWLSYKSYETKKKGVGKVEEKQAILHEEGKMDDCLDFSRSQEEESKTARVIRKCSSLFTQFITALETLQSNRRHS--IFFQKVNLNEMVMCLEDLINYFSQPEDDMEHEEKQNRFRALRNRQDLFQEEGVLNLILEAIDKINIITSQGFLASFLAGDETGQSWDLISTYLYQLLAAIIKGNHTNCAQFANSNRLNWLFSRLGSQASSEGSGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLEKHGRDPKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTLLVDHVASIRPNIFVGRVDGSSMYQKWYFEVTMDHIEQTTHMMP-HLRIGWANTSGYVPYPGGGKKWGGNGVGDDLYSFGFDGAFLWTGGRKTLVVDALPEEPFIRKGDVIGVAIDLSVPIITFTFNGVKVRGSFRDFNLDGMFFPVMSCSSKLSCRFLFGGDHGRLKFAPPMGFSALVQCLMPQQILSLDPCFYFG--NLAKNVLAGPWLIEDDTAFVPKPVDTTGVTLPSSVDQIKEKLAENIHEMWALNKIEAGWSWGEHRDDYHRIHPCLTHFEKLPAAEKRYDNQLAVQTLKTIISLGYYITMD--KPPARIRPVRLPNEIFMQGNGYKPAPLDLSAVTLTPKLEELVDQLAENTHNLWARERIQQGWTYGLNEDSENHRSPHLVPYAKVDEAIKKANRDTASETVRTLLVYGYVLDPPTGEGTEALLAEAQRLKFAGFRTYRVERNYAVTSGKWYFEFEVLTSGPMRVGWARADCYPGAMLGSEDTSWAFDGHNVTKMHAGSIEHFGVRYEAGDVIGCFIDVKEQTISFSLNGELLMDALGGETTFADVTAEGVGFVPACTLGVGQKARLIYGQDVDSLKFFTTCGLQEGYEPFCVNMRRPVTHWYTKDQPIFENTEEMPDCRIDVTRIPGGADTPPHLKISHNTFET-MEKANWEFLRLSLPVTCMGEFISEQEKARRWDEIKNRQYRLMREAEIAAQMQVQTQAAHMDHMLKGGFNMNDIKGLTRNFDEHADAEADHMMRGPNRPPRKGSLTRNITFETDMSAALDEMQRSTSVLDMNGLGEEMDDKKKRGRSPFKFFSKKSRDQSREKMGARTLDTSLERRNTVAHGRNVVNQQMTTRAPTLRLNNAEIPPSPVPQGPKQLSGSNLGQQPVETSGDEMFDAECLKLINEYFYGVRIFPGQDPTHVYVGWVTTQYHLHSREFNKNKVRRGSVYIEDDYEMAIERIDRQSCYVVRADELFNEVTQDASGKGASQGMFVGCFVDTATGIIRFTCEGKDTSHRWMMEPDTKLFPAIFVEATSKEILQIELGRTPTTLPLSAAVLPTSDKHINPQSPPRLKVQCLRPHQWARVPNTALQVHALKLSDVRGWSMLCEDPVSMLALHIPEEDRCIDILELIEMDKLLSFHAHSLTLYAALCYQSNYRAAHALCQHVDQKQLLYAIRSEYMSGPLRQGFYDLLIALHLESHATTMEVCKNEYITPLGAELKELYSDEEMQHSLRSLVTESVRPQLRMTEITPPVIATSSMPSVSSEPIPDIDQLY--SPKFPLEVVRQFVMEALKDAVEINQVHNRDPIGWTNENLFLPLIKLTDRLLLVGVLTDEDVQRLLVMIDPETWD-----------------------------------------------------------------------------------------------QAFEREGKDEHRKGLLTMKMAEGAKLQMCYLLHHLYDTQLRHRVESIIAFSHDFVGDLQTDQLRRY-IEIKQSDLPSAVAAKKTKEFRCPPREQMNQILCFKNLEPDDQDNCTCGLELRGRLGDFHDSLMQKVSLNALQEPDGVEGTAIEEVKTGPITKIYNFINTVKELEEGPKEVEEPEKKTPEEVFRKVLIKTIVSWAEESQIENPKLVREMFSLLLRQYDTVGELVRALEKTYVINTRARDDVAEMWVGLSQIRALLPVQMSQEEEELMRKRLWKLVNNATFFQHPDLIRILRVHENVMAVMMNTLGRRAQAQSDAPTQSEVAEGAPSKEKDTSHEMVVACCRFLCYFCRTGRQNQKAMFDHFDFLLDNANILLARPSLRGSTPLDVAYSSLMENTELALALREHYLEKIAVYLSRCGLQSNSELVEKGYPDLGWDPVEGERYLDFLRYCVWVNGESVEENANLVIRLLIRRPECLGPALRGEG-EGLFRAIVEANRMSERISDRCKMQDEAEGTIAGLNFTHPLPEGEEDEDYIDTGAAILNFYCTLVDLLGRCAPDASVIEQGKNESLRARAILRSLVPLEDLQGVLSLKFTLSQTAPGEEKPKSDMPSGLLPNNKQSIVLFLERVYGIEAQDLFYRLLEDAFLPDLRTATILDKSDGSESDMALAMNRYIGNSILPLLIKHSKFYNEAENYASLLDATLHTVYRLSKNRMLTKGQREAVSDFLVALTSQMQPAMLLKLLRKLTVDVSKLSEYTTVALRLLTLHFDRCAKYYGSTQGQGSYGASSDEEKRLTMLLFSNIFDSLSNMDYDPELFGKALPCLIAIGCALPPDYSLSKNTDEDYYGRQMGAPDQPQYMPNPIDTNNVHLDNDLNSLVQKFSEHYHDAWASRRLEGGWTYGDIRSDNDRKHPRLKPYNMLSEYERERYRDPVRECLKGLLAIGWTVEHS-EVEVALNHRGSTRRQSKPQINEFQNEGSPFNYNPHPVDMSNLTLSREMQNMAERLAENSHDIWAKKKNEELNGCGGVIHPQLVPYDLLTDKEKKKDRERSQEFLKYMQYQGYKLHKPSKGGAVEEGGATQAAVELRFSYSLLEKLIQYLDRATINMKLLKPSTTFSRRSSFKTATRDIKFFSKVVLPLMEKYFSTHRNYFIAIATATNNIG-AASLKEKEMVASIFCKLAALLRNRLSAFGPDVRITVRCLQVLVKGIDARTLTKNCPEFIRTSMLTFFNQTSDDLGNTILNLQDGKYSHLRGTHLKTSTSLGYVNQVVLPVLTAMFDHLAACDYGSDLLLDEIQVASYKILAALYHLGTDGTLTHDRKYLKTEIERHRPALGSCLGAYSSCFPVAFLEPHLNKHNQYSLLNRIADHS---LEAQDIMVKMESCMPNLETILAEVDQFVESDKTYNDAPHIIDVILPLLCAYLPFWWSQGPDN----VSPTSGNHVTMVTADHMNPLLRNVLKMIKKNIGNDNAPWMTRIAAYTQQIIINTSEELLKDPFLPLAERVKKRTENMLHKEDSMRGFIKSATDDTSQVETQLQEDWNLLVRDIYSFYPLLIKYVDLQRNHWLKDN-IPEAEELYNHVAEIFNIWSKSQYFLKEEQNFISANEIDNMALIMPTATRRSAISEGAPAVGGKVKKKKKNRDKKRDKDKEVQASLMVACLKRLLPVGLNLFAGREQELVQHCKDRYLKKMPEYDVIEFARNQLTLPDKLDPSDEMSWQHYLYSKLGKTEEPVDEQALEKANVNSNEKGKDKTQETVDRIVAMAKVLFGLHMIDHPQQQSKNVYRSVVSIQRKRAVIACFRQTSLHSLPRHRACNIFARSYYEQWLQ-EENVGQEVMVEDLTQTFEDSEKSKKEGEETDSKPDPLTQLVTTFCRGAMTERSGALQEDLLYMSYAQIAAKSTGKEEEEGGDEEGGEGGEEGEGTS----IHEQEMEKQKLLFHQARLSNRGVAEMVLLHISASKGIPSEMVMTTLNLGIAILRGGNIDIQMGMLNHLKEKKDVGFFTSIAGLMNSCSVLDLDAFERNTKAEGLGVGSEGA--------AGEKNMHDAEFTCALFRFIQLTCEGHNLEWQNYLRTQAGNTTTVNVVICTVDYLLRLQESIMDFYWHYSSKEIIDPAGKANFFKAIEVASQVFNTLTEVIQGPCTLNQQALAHSRLWDAVGGFLFLFSHMQDKLSKHSSQVDLLKELLNLQKDMITMMLSMLEGNVVNGTIGKQMVDTLVESASNVELILKYFDMFLKLADLIESPSFHEVDMKNEGWVTPKDFREKMEQSKNYTPEEMDFLLACCERNHEGKIDYRAFVEHFHEPSKEIGFNLAVLLTNLSEHMPNEPRLARFLETAGSVLNYFEPFLGRIEILGSSKRIERVYFEIKDSNIEQWEKPQIRESKRAFFYSIVTEGGDKEKLEAFVNFCEDAIFEMTHASGLMATDDGGGNVKRD-------TAYSSYMSEEEEERAARDPIRRTITAVKEGLKFGVHMLSPANIKHQIGVMQTKSIPELIVGFFKIIFYIFYYTGYAHFCVVRYIFGILLNLMRGPAPEQEEEPVVEEETFGRALPPLPLEEPPGTVQAFGLDINKEENGMYKVVVHESPANSSMEEGGESSP---------------EDGAAASGELVEGEPHQEPIS-----IVDLLGGEAAKKAAQERQEAQKAQ--EAAMASIEAEAKK-------------------SSSAPQETPAVHQID-------FSQYTHRAVSFLARNFYNLKYVALVLAFSINFMLLFYKVTSFTEEADSSAEEELILGSGSGGGADITGSGFGGSGDGGSGDGEMEDEIPELVHVDEDFFYMEHVLRIAACLHSLVSLAMLIAYYHLKVPLAIFKREKEIARRLEFEGLFIAEQPEDDDFKSHWDKLVISAKSFPVNYWDKFVKKKVRQKYSETYDFDSISNLLGMEKSTFAAQ--------ESEETGIFKYIMNIDWRYQVWKAGVTFTDNAFLYSLWYFSFSVMGNFNNFFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLTVMLLTIIVYIYTVIAFNFFRKFYIQEEDE-EVDKKCHDMLTCFVFHLYKGVRAGGGIGDEIGDPDGDDYEVYRIIFDITFFFFVIIILLAIIQGLIIDAFGELRDQLESVKDNMESNCFICGMGKDFFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRSWDFFPVGDCFRKQYEDELSGGGGGG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: .. ::::.****:* *.*.*:** ::**:.****** **** :: : *****: * *::**:********::: : . . *.********:****** :* ***:**:** * .***:*******.: *******:******************:*****::***** : . : *:*** * *.::* : . *:: **.***:*** ******. : : :. . **** * ::******** * *:*..:.* :.:*:**:***:** : :.: *::*. .:* ::**:* .*: : .* .:*:* :* * ****:: :*** :.***:* : :.* :* :::*:**:**:***.* .:*.* **::**:* . .*:.***..*:::..: : . : :: :::.*:*** ** *.::::*****.::*:*****.******::.::*:.:*::*: .: ..::.* . :::.:**. * . :*:***::*:**::*** *. . *:**.*:*. :* **:*:**:*:**:***.**:::::*** **:**:****: *********** *******.*: * : ****::***** ::::*:*:*****:* :*:: * ***:*: :*.: . ***:*** :.** ****.*: **********:*:**** **** *.. * : :: **:. .:***** *:* :** *:* *..*****:****:* *: :. ***:** :* :** ** *::. :.::*:: * ::* : . * ** .. *.* **** :.**. :::*:****** **:**:.:** **::* *** :::****..*..** .*: *: :: :****:::** :: * *. .:: :** : :* **********. * *** **::**** **:***:*: ***:*. :* :*.*:**** :** *::***: . :****: *** ::** * : :.: * :*.*:.*:* .*:******.:* * .:****.. .. **::: ::.*:*.. : * * * ** ::.***:**:**:.*:.* *:****:*:. *.* :* :: **:*.*:** .* .:: **:*.**::*: ******:***.:**:* :* *::*. * * . : :*:*: * .::.* *:::*.*: : .: *:***:*: * * . . .: : .: .. : :::*: :: : .:.:: .: * .. ::*. . :.::.. .. .*:: :: * :. : : . . *:*.**:*.**:*: *:.****.:** :. *: *** :* : *: . :. ..**:* ..:: . * .: .:.:**:** **:: **.:**: . : :**:******:* .: ::::*.:* . :*:***:: :. *: **.****.:* * * *:*:** * .: : .: ** : * :*: *:*******: * . :: : : : . . :..:. * ***: **::*:.. :.**:* *:*****::**** . .*:*.*: * : : . ..: * : * :.. : ** :**: ::: .: * :**. . ***:* : * *:*::** . **::*:: *:**:::* :*:*..: . :: :*** **:.*..***** **.:: * :*:****:: **:. :*..:* :* ** :: :.:* :*::*:***.**:**:* :: **: ::::*. ::* * **..*: : .:: * : * : . : : : :. ::: *: .*: ::::: : :: **:*. ::.*:*** ***** **** :***:*** ::* *. : :*. .: *.***:** ***. :**.** : : :::.* .*:***:*:* * :**.** **:*.** *. *** .**. ********** .****::****:.:**:*:.* *. ::******** :* ::*.******:*: ** :. **: ***** . *: *****:**:* **:******:.*:***********:*:*****:***:******** .**: ** ** ::** : :. . . * :*: :. * **:.**.:*:********: :*: **.*:** *********::** *::** . :. . . :..*.:.::*::* .:****:*****: **:: ::*: .****:*:*: **.: * ***:.**: ::***: * : : ::: * ::*: ***:****:.* ***.**:.:.: *::* ::*:** :***:*..**. *.*::.:.*:*** *::** *** . * ..:*.:*:** :** ** .**:**:: .:* **: *:**: **. *:**** :. :.: :.* . :: *.*::* *. : :.*:.::::::*: *: ** :::..*::*: .:: :.** *:**: :** ::* ** *::*.:*.::* **:::: : * .: .:*: *:. :: . *.*:* *:* :*****:* ***:**** *: *.:**: **:. ** ** ***** ** *** :***:: *:**::* :** : : *. : :::* **::.:*::*::::* : : *:. .: * * . .. ::****:*::***:::**..* **:: .: . * ** *****::*:***::**:*:*: **.*. *.**::*.:.:****: *. **::::.: **:.:::*: : : **: ** *: . .. .: *.. .:*****::*:*:* ::*.*::**::*::.*: :.::* *** .. *: *****.**. ::.:***:***.**::* *: . : :. * : : :: :* *: :: ::. :.**. *.: **:*:: **:** *** **.:* : .. * **:: :* ** .::::: :*:* *:*.**.*:*.::* *: .: *:*:. *:* :::**: ::: :*: :* ... : .: * ::::: :* **:*::*****:*** :* * *.:. .*: *.: . *:.* ::* :: . * **. ::.*: *:*.. .**:**:** **::**:***: : :*:*: .* ** * .: :* ** :*:* * .*:: . .: ** ** : * . * .:: * *: :: **: :. :** :..* *::.::* **:***:**** *.*:.** ***.*:* .* *: * :: *::**::: *:.*: * * :.***** **: *.* *:**:* *: * ***:**:* *** :* . * * . . *::****:**::*:** .**.***** ***.** .. ** :**:***:**.*** ::* **::**:**:**** *: .**::* . :*: : * : . . *** * * *** ****:** ***** ::*******:*.***:*::************** ****:**.*::*: ** ** **: **.****:*** ****** ***:********** ***.:*:** **::.***: ******:*****:.*:**:******** *.:**** ****:****:***:******* *:: * :*:: . .* :: ***:: *:..*::: *::***:*.* :.: *: . *..:*:**:::****:**********:*::.** .*** * *:*:**.*:******:*:*::***:****.: * *** **::**** *::.:*.***: **:* **.****:**** *: : : . . . : . . . : :: .:::: :: : * ... ::: . . : :: : * . : : :. * :. * * . : * . . :.. . : ... *:: : * : * . : : * : *. *. * * .. . :. . :. : :. *:****.::::**.***::**:******:. . *. . ** * ...: . . . .: ::: .::*. **: .* : **::::: :*.* **:**.*******:**:***:**:*:*** ***.*.:**:**:.: *** ********:** :*:.: :. : *::****: ::: : .:: :: .** :**:** ** ****:*** ** :*::*::******.****:*:*.*******.*********::** **:::**:***:********* :.*** * * **.**:**::**:* ************ ** **:**:**::**********:******************** *.**::**::*****:*.*:** .****:**. :************:**** :**:****:***:***:*.*****.**********:*. ", "identical_positions": 1976, "similar_positions": 1584, "identity": "37.04%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020114-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35346-1", "uniprot_id": "FAK1_RAT", "id": "O35346-1", "name": "Focal adhesion kinase 1", "aln": "--------------------------------------MAAAYLDPNLNHTPSSSTKTHLGTGTERS---PGAMERVLKVFHYFESSNEPTTWASIIRHGDATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHP----PEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQDIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQTIQYSNSEDKDR----------------------KGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIP---KLANNEK--QGMRTHAVSVS------ETDDYAEI--IDEEDTYTMPS-------TRDYEIQRERIELGRCIGEGQFGDVHQGVYLSPEN------------------------PALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS-KGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKVQQEERMRMESRRQATVSWD-SGGSDEAPPKPSR-----------------------------------------------------------------------------------------------------------------------------------------------------------------PGYPSPRSSEGFYPSPQHMVQTN--------------------------------------------------------------HYQISGYPGSHGIPAMAGSIYPGQASL------------------------------LDQTELWNHR-PQEMSMWQPSVEDS---------------AALDLRGMGQVLPPHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSFQGPTGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLSNLSSISSPAESYNEGVKPWRLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPILPASTHREIEMAQKLLNSDLGELISKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH---------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P34152-3", "uniprot_id": "FAK1_MOUSE", "id": "P34152-3", "name": "Focal adhesion kinase 1", "aln": "--------------------------------------MAAAYLDPNLNHTPSSSTKTHLGTGMERS---PGAMERVLKVFHYFESSSEPTTWASIIRHGDATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHP----PEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMQEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQTIQYSNSEDKDR----------------------KGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIP---KLANSEK--QGMRTHAVSVS------ETDDYAEI--IDEEDTYTMPS-------TRDYEIQRERIELGRCIGEGQFGDVHQGVYLSPEN------------------------PALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS-KGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKVQQEERMRMESRRQATVSWD-SGGSDEAPPKPSR-----------------------------------------------------------------------------------------------------------------------------------------------------------------PGYPSPRSSEGFYPSPQHMVQTN--------------------------------------------------------------HYQVSGYPGSHGIPAMAGSIYQGQASL------------------------------LDQTELWNHR-PQEMSMWQPSVEDS---------------AALDLRGMGQVLPPHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSFQGPTGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLSNLSSISSPADSYNEGVK---LQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPALPASTHREIEMAQKLLNSDLGELISKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH---------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05397-1", "uniprot_id": "FAK1_HUMAN", "id": "Q05397-1", "name": "Focal adhesion kinase 1", "aln": "--------------------------------------MAAAYLDPNLNHTPNSSTKTHLGTGMERS---PGAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHP----PEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDR----------------------KGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGTSQSFIIRPQKEGERALPSIP---KLANSEK--QGMRTHAVSVS------ETDDYAEI--IDEEDTYTMPS-------TRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPEN------------------------PALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS-KGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWD-SGGSDEAPPKPSR-----------------------------------------------------------------------------------------------------------------------------------------------------------------PGYPSPRSSEGFYPSPQHMVQTN--------------------------------------------------------------HYQVSGYPGSHGITAMAGSIYPGQASL------------------------------LDQTDSWNHR-PQEIAMWQPNVEDS---------------TVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSYNEGVK---LQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH---------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HF58-1", "uniprot_id": "A0AC58HF58_DANRE", "id": "A0AC58HF58-1", "name": "Focal adhesion kinase 1", "aln": "MESSGCSPFPLCWARGACVYSYPPPLPKYDGQLAPTKAMAAAYLDPNPTHALNQGVKPRFSSGMERT---AAALERVLKIFHYFESSSEPCSWASNIRHGDSTDVRGIIQKILDIHKVRCVSCFGLRLSHLRTGEIHWLHPDMGVSHVRERYEHSHP----QDDWRYELRIRYLPKGFLNQFTEDQPTLNYFYHQVKSDYMMEIADQVDQDIALKLGCLEIRRFFRDMPGNALDKKSNYELLEKDVGLRRFFPKSLLDSVKAKSLRKLIQQTFKQFANLNNEQCMLKFFEILSPIYRFDKECFKCALGSSWVISVELAIGPEEGISYLTDKGSNPTHLANFTQVQTIQF---EERER----------------------KGMLLLDVAGAPEPLTVTTTTLNTAENMADLIDGYCRLVSGTSSSFIVRVQKEGERALPSIPKAPKSANHEKRLQGVRAKAISISDDIGGDETDDYAEI--IDEEDTYTMPSKYYGLDEARDYEIQRDRIELGRCIGEGQFGDVHQGIYICPDT------------------------PALSVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQIRKYNLDLASLILFSYQLSTALAYLESKRFVHRDIAARNVLVSSVDCVKLGDFGLSRYMEDSSYYKAS-KGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMYGVKPFQGVKNNDVIGRIENGERLAMPPNCPPTLYSLMTKCWAYDPSKRPRFTELKGQLSTILAEEKAQQEERSRMEMRRQVPVSWD-SGGSDEAPPKPSRRRPLQHSFSMDCLSPSVSTSAASRPPQQPFGSQISLCFRQTEPSASPLKPCVKS-------------------------------IINPSAHMQQNTPQLSIQTQRPLLLEPLPLHCSLLFPQGPRTRPSVPPGIFFDPYYPSMQQLSLSHAPYRFTQPSRPGYPSPRSSEGFYPSPQHMGQHN--------------------------------------------------------------HYQMAGHSGPHGLLSVPGGLYPPQATVT----------------------------GLDPHDSWNHRRVAQDHMWNPSMEDG---------------VALRGG------LSQLMEEQLILQQQQMEDDQRWLEHEERLLKPDGRSSRGSTERDDGSLQGPTGNQHIYQPIGKAEHAAPPKKPPRPGAPSHAAGVSGLN-PTESYNEGVK---IQPQEINPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPAHTHREIEMAQKLLNSDLAELINKMKLAQQYVMTSLQQDYKKQMLTAAHALAVDAKNLLDVIDQARLKLLGQARPH---------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7YZL9-1", "uniprot_id": "B7YZL9_DROME", "id": "B7YZL9-1", "name": "", "aln": "------------------------------------MNTAGATSQPPPTKNEINSEEYLIHVHMPNKSFKAVRFNVKETVFHVIRRTVEDLGTDGRTPSIQRYACRMLNMITKEVIWLARSTSMQKVLSHILTPGCSNVDCPNNQSELDEVLLEHGRRITDNRVWRVELRVRYVPNNIQELFEEDKATCFYYFNQVKEDFIQANVTAIDTEVAVQLCCLGIRHYFKNITVKAPDKKQHIDYIEKEIGFKSFLPQSVIATSKPKNLKKLIQVGYKKVYNYNDIEYLTRFFDLLKNIYLTNFEQFSVTLSSAWNISGILHVGPHIGISYQTHPQASLKNVAQFKDVVSIKTCTLPKEKLSKSGENTTEPELQNFNCNCQKIKTQIKISASNNVEDLVITCNGINTAESIADLIDGYCRLLSKDLEFTIWHRETNASNEDSAKA----LPNDATLGSNKSTSSQGKP-----MLTDDYAEIGLLEGEGDYSTPT-------VRNYELDRALITPSAKIGVGQFGDVYVGTYTLPKLGKGKNLAGNGKNSNSDQRNADSRPDVIQVAIKTCKANDDPEKTENFLAEAYIMQKFDHPHIIRLIGICSVMPIWIVMELAKLGELRAYLKTNSERLSHGTLLKYCYQLSTALSYLESKKFVHRDIAARNVLVSSPTCVKLADFGLSRWVSDQSYYHSTPTVALPIKWMSPESINFRRFTTASDVWMFGVCIWEILMLGVKPFQGVKNSDVILKLENGERLPLPPNCPPRLYSLMSQCWAYEPLKRPNFKRIKETLHEILIEDSINSSETLKREQRKVASMSWIGSDDIDIPPSKPSRVMHDPDITGLMPETTGLPQTYIIAQNPAVLAKLMMENQKRGINPAAYTTPASVFNTLAVGLDDSNPNVSLKTTKLPAADLLKLDPIAESERLRSQFSANSSASQLANPLTASVNPHESLNSHQAGMFTGSLPSKSSFVVCPPQTEEHMQAENISNPSVSKVSGYSLYGSLERHQPPPAKAMHSKGGSLERHQSLMSAQNLVFYNTKPPPNCTNTAERSRSMERNTYFHAYRQQMKTSIECEALPEEIYDFGGIGLKTCVSARQQPKFSPMVNVRPAELGQVQNTDCMGLQQNIPMDSFGVISPHNLDESLRHQREMERQWMTSGPQSITVNPNISISEGAACLATLQAEAMGNQGIHNVLGEKLRQQQKDSNSDSEWLIQEELLR--SCSIPQGSLNDHQAQMFKLDFMSAGPSSLPDCSNSSSRPMTPNANLSSLKSNHSSADHLSSLTSAEEQMGSNARNLGSAVPSRPPNRADDEVYCATTLVVKSIMALSQGVEKANTEGYLELVKNVGVKLRNLLTSVDKISIIFPAQALKEVQMAHQVLSKDMHELVSAMRLAQQYSDTTLDCEYRKSMLSAAHVLAMDAKNLFDVVDSIRQRYQHLFPPSATKETSCSSSFESTSGSIVAEPVNDLGGYIKTSTSGDLLQNTGIYDNDLHHSFNSQLQLQNPKASIDLSGGGSLQRGMSLGLDTTRSTNEPLRIVEETLGSPGEHMYCNTSALHGHA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 361, "similar_positions": 343, "identity": "23.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020117-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZMA3-1", "uniprot_id": "D3ZMA3_RAT", "id": "D3ZMA3-1", "name": "Diencephalon/mesencephalon homeobox protein 1", "aln": "MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLA-----DIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQK--EAEGSHGEG-KMETP-------------ASNTQLEAEQPPSLPSGDPPAELQLSLSEQSASESAPED-QLDREEDSRA--EEPKAEKSPGSESKVLGCKRASPKADSP-GSLAITPAAPAG-SLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAAAAVPYLGVNM---APLSSLHCQSYYQSLSAAAAAHQGVWGTPLLPAPPTGLAPASAALNSKTTSIENLRLRAKQHAASLGLDTLPN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZK4-1", "uniprot_id": "DMBX1_MOUSE", "id": "Q91ZK4-1", "name": "Diencephalon/mesencephalon homeobox protein 1", "aln": "MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQK--EAEGSHGEG-KVEAP-------------ASDTQLETEQPPGLPSGDPPAELQLSLSEQSASESAPED-QLDREEDSRA--EEPKAEKSPGSESKVPGCKRGSPKADSP-GSLAITPAAPGG-GLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLMHYSSFEVGGPAPAAAAAAAAAVPYLGVNM---APLSSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPTGLAPASAALNSKTTSIENLRLRAKQHAASLGLDTLPN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFW5-1", "uniprot_id": "DMBX1_HUMAN", "id": "Q8NFW5-1", "name": "Diencephalon/mesencephalon homeobox protein 1", "aln": "MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQK--EAEGSHGEG-KAEAP-------------TPDTQLDTEQPPRLPGSDPPAELHLSLSEQSASESAPED-QPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSP-GSLTITPVAPGG-GLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAP-AAAAAAAAVPYLGVNM---APLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTSIENLRLRAKQHAASLGLDTLPN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JI10-1", "uniprot_id": "DMX1A_DANRE", "id": "Q8JI10-1", "name": "Diencephalon/mesencephalon homeobox protein 1-A", "aln": "MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKDVSTDGALAASDKDEAPSTLNLENQPPSSTSSSSSMEAEAAPHALGSELSVELNVTSAEQSGSESATEDNATDKEEEIKQHREDLKVEKEPAPGNLSPLCKRLSPKPDSPLGSPAISSSSSGVTGGISQSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYPSFDMATPSS---------IPYLGMNVNMPAPLGSLPCQSYYQSLSHHA---QQVWNSPLLQAS-GGLP----SHNSKTTSIENLRLRAKQHAASLGLDTLPN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************************************************** ************************************************************************************** .::*: . . * *:* :..:.:::* .* ..: ..**::: :***.****.** *:**: : *: *.**.*.. . *** ***.*** ** :*:. :.. . :. ****************************:**.**::. *:. :****:*: ***.** ********* * * **.:*** *. **. : ****************************", "identical_positions": 264, "similar_positions": 62, "identity": "65.19%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020122-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A2T5-1", "uniprot_id": "D4A2T5_RAT", "id": "D4A2T5-1", "name": "", "aln": "MAQ-RYDELPHYGGMDGVGVPASMYGDPHAPRP-----IPPVH--HLNHGPPLHATQ-----HYGA--HAPHPNVMPAS--MGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHN-------------PSSWRDH-----DDATSTHSAGTPGPSS------------------------------------------GGHASQ---------SGDNS--SEQGDGLDNSVAS-PGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGLQSMPGDYVSQGGPVGMGMAQPSYTPPQMTPHPTQLRHGPPMHSYLPSHPHHPAMMMHGGPPTHPGMTMSAQSPTMLNSVDPNVGGQVMDIHAQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97367-1", "uniprot_id": "MEIS2_MOUSE", "id": "P97367-1", "name": "Homeobox protein Meis2", "aln": "MAQ-RYDELPHYGGMDGVGVPASMYGDPHAPRP-----IPPVH--HLNHGPPLHATQ-----HYGA--HAPHPNVMPAS--MGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHN-------------PSSWRDH-----DDATSTHSAGTPGPSS------------------------------------------GGHASQ---------SGDNS--SEQGDGLDNSVAS-PGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGLQSMPGDYVSQGGPMGMGMAQPSYTPPQMTPHPTQLRHGPPMHSYLPSHPHHPAMVMHGGPPTHPGMTMSAQSPTMLNSVDPNVGGQVMDIHAQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14770-1", "uniprot_id": "MEIS2_HUMAN", "id": "O14770-1", "name": "Homeobox protein Meis2", "aln": "MAQ-RYDELPHYGGMDGVGVPASMYGDPHAPRP-----IPPVH--HLNHGPPLHATQ-----HYGA--HAPHPNVMPAS--MGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHN-------------PSSWRDH-----DDATSTHSAGTPGPSS------------------------------------------GGHASQ---------SGDNS--SEQGDGLDNSVAS-PGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGLQSMPGDYVSQGGPMGMSMAQPSYTPPQMTPHPTQLRHGPPMHSYLPSHPHHPAMMMHGGPPTHPGMTMSAQSPTMLNSVDPNVGGQVMDIHAQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AK57-1", "uniprot_id": "A0A8M3AK57_DANRE", "id": "A0A8M3AK57-1", "name": "", "aln": "MAQ-RYDELAHYGGMDGVG----MYGDPHAPRP-----LPQVH--HLNHGPPLHASQ-----HYGT--HAPHPNVMPTS--MGSAVNDVLKRDKDQIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHMGNGW-IRSDRLQNPASWRDH-----DDATSTHSAGTPGPSS------------------------------------------GGLASQ---------SGDNS--SEQGDGLDNSVAS-PGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGPMSG----------MGMNMG------------------------------------------------MDGQWHYM------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O46339-1", "uniprot_id": "HTH_DROME", "id": "O46339-1", "name": "Homeobox protein homothorax", "aln": "MAQPRYDDGLHGYGMDSGAAAAAMYDPHAGHRPPGLQGLPSHHSPHMTHAAAAAATVGMHGYHSGAGGHGTPSHVSPVGNHLMGAIPEVHKRDKDAIYEHPLFPLLALIFEKCELATCTPREPGVQGGDVCSSESFNEDIAMFSKQIRSQKPYYTADPEVDSLMVQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDTTKPPELGSANGEGRSNADSTSHTDGASTPDVRPPSSSLSYGGAMNDDARSPGAGSTPGPLSQQPPALDTSDPDGKFLSSLNPSELTYDGRWCRREWSSPADARNADASRRLYSSVFLGSPDNFGTSASGDASNASIGSGEGTGEEDDDASGKKNQKKRGIFPKVATNILRAWLFQHLTHPYPSEDQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVYTPHPGPSG---YG--HDAMG-YMMDSQAHMMHRPPG-------------DPGFHQGYPHYPP------------------------------------------AEYYGQHL------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53147-1", "uniprot_id": "TOS8_YEAST", "id": "P53147-1", "name": "Homeobox protein TOS8", "aln": "---------------------------------------------------------------------------------MGTSIVNLNQK-----IELPPIQVLFESLNRENETKPHFEERRLYQPNPSFVPRTNIAVGSPVNPVPVSSPVFFIGPSPQRSIQNHNAIMTQNIRQYPVIYN-----NNREVISTGERNYIITVGGPPVTSSQPEYEHISTPNFYQEQRL-------------AQPHPVN------ESMMIGGYTNPQPIS-------------------------------------------ISRGK----------------MLSGNISTNSVRG--SNNGYSAKEKKHKAHGKRSNLPKATVSILNKWLHEHVNNPYPTVQEKRELLAKTGLTKLQISNWFINARRRKIFSGQNDANNFRRKFSS-----------STNLAKF------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P41817-1", "uniprot_id": "CUP9_YEAST", "id": "P41817-1", "name": "Homeobox protein CUP9", "aln": "-------------------------------------------------------------------------------MNYNCEIQNRNSKNVDNQVSLPPIQVLFNSIEKRSMPELAFSNIEYSHGN----LRSSTEEQNYPAPVLLPQHHSIAYPAINSGGTSTTATPTASTVETSKTSSSAMDTQSQYGSSKKSK--------SASDDAKPCYKSAPIYEIINKEKD-------------------------------AGAQYNRPFS---------------------------------------------------------------------------------DFVESKSRRKQNSGRRSNLPKETVQILNTWLLNHLNNPYPTQQEKRELLIKTGLTKIQLSNWFINVRRRKIFSDYYTLVNSIPNDNANNTPVERVQNVSAYHNTLSATNNTMYDATSTCSTDYELSKRFAHAPVTRRKKLIDRLEELKKLSNPDMN---------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: * : :* ::: . . : : . : . * : . : . : . : . : . * * . . :: :*. :** :..*:. ** :*:.:***: ::*::* .**** :*:.*****.*** : . . . ", "identical_positions": 30, "similar_positions": 56, "identity": "5.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020122-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70477-1", "uniprot_id": "PKNX1_MOUSE", "id": "O70477-1", "name": "Homeobox protein PKNOX1", "aln": "MMATQTLSIDSYQDG-QQMQVVTELKTEQDPNCSDPDAEG-VSPPPIESQTPMDADKQAIYRHPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKDGKPFFCEDPETDNLMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQSQQIQSAITGTLSPQGIVVPASALQQGNVTMATV------AGGTVYQPVTVVTPQGQVVTQALSPGTIRIQNSQLQLQLNQDLSILHQEDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKPAQNRPVQRFWPDSLASGVAQATPSELAMSEGAVVTITTPVNMNVDSLQSLSSDGATLAVQQVMMAGQSEDESVDSTEDEGGALAPTHISGLVLENSDSLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5BJP1-1", "uniprot_id": "Q5BJP1_RAT", "id": "Q5BJP1-1", "name": "", "aln": "MMATQTLSIDSYQDG-QQMQVVTELKTEQDPNCSDPDAEG-VSPPPIESQTPMDADKQAIYRHPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKDGKPFFCEDPETDNLMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQSQQIQSAITGTLSPQGIVVPASALQQGNVTMATV------AGGTVYQPVTVVTPQGQVVTQALSPGTIRIQNSQLQLQLNQDLSILHQEDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKPAQNRPVQRFWPDSLASGVAQATPGELAMSEGAVVTITTPVNMNVDSLQSLSSDGATLAVQQVMMAGQSEDESVDSTEDEGGALAPTHISGLVLENSDSLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55347-1", "uniprot_id": "PKNX1_HUMAN", "id": "P55347-1", "name": "Homeobox protein PKNOX1", "aln": "MMATQTLSIDSYQDG-QQMQVVTELKTEQDPNCSEPDAEG-VSPPPVESQTPMDVDKQAIYRHPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKEGKPFFCEDPETDNLMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQSQQIQSAITGTISPQGIVVPASALQQGNVAMATV------AGGTVYQPVTVVTPQGQVVTQTLSPGTIRIQNSQLQLQLNQDLSILHQDDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKTAQNRPVQRFWPDSIASGVAQPPPSELTMSEGAVVTITTPVNMNVDSLQSLSSDGATLAVQQVMMAGQSEDESVDSTEEDAGALAPAHISGLVLENSDSLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B5L4-1", "uniprot_id": "A0A8M3B5L4_DANRE", "id": "A0A8M3B5L4-1", "name": "", "aln": "MMAAQSVSIDKYPEGDQQMQVMEQSENDLKKGFSNGNTGNSSSPVSNEPQTQMDIDKACIYRHPLFPLLALLFEKCEQSTLGSDCVTSASFDVDIENFVRSQEKDGKAFFSEDPDLDNLMVKAIQVLRIHLLELEKVSDLCKDFCSRYISCLKAKMNSETLLSGDPGSPYSPVHD-QLSNPFSGPLSPQSLLIPSSGLQQGSVTVTTVNPSQVATGNTVYQPVTVVTPQGQVVTQAISPGALHIQNSQLQLQLNQDLSFFGGDDSSPKNKRGVLPKQATNVMRSWLFQHIAHPYPTEEEKKQIATQTNLTLLQVNNWFINARRRILQPMLDANSTEASKSKKKVAQSRPLHRFWSDSIASTGSQQ---QLTMPDGSLVTVG----MNVDGFQALSSDGATLAMQQVLMGNHSEDETDESGNEDDTDMSTANMPGLGLDVSD---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53147-1", "uniprot_id": "TOS8_YEAST", "id": "P53147-1", "name": "Homeobox protein TOS8", "aln": "-MGTSIVNLNQKIEL-PPIQVLFESLNR-------------------ENETKPHFEERRLYQP--------------------NPSFVPRTNIAVGSPVNPVPVSSPVFFIG-PSPQRSIQNHNAIMTQNIRQYPVIYNNNREVISTGERNYIITVGGPPVTSSQPEYEHISTPNFYQEQRLAQPHPVNESMMIG--------------------GYTNPQPISISR--GKMLSGNISTNSVRGSNNGYSAKE---------KKHKAHGKRSNLPKATVSILNKWLHEHVNNPYPTVQEKRELLAKTGLTKLQISNWFINARRRKIFSGQN----DANNFRRKFSSSTNLAKF-------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P41817-1", "uniprot_id": "CUP9_YEAST", "id": "P41817-1", "name": "Homeobox protein CUP9", "aln": "-MNYNCEIQN---------------------------------------RNSKNVDN---------------------------QVSLPPIQVLFN-SIEKRSMPELAFSNIEYSHGNLRSSTEEQNYPAPVLLPQHHSIAYPAINSGGTSTTATPTASTVETSKTSSSAMDTQSQYGSSKKSKSAS------------------------------DDAKPCYKSAPIYEIINKEKDAGAQYNRPFSDFVESK-------SRRKQNSGRRSNLPKETVQILNTWLLNHLNNPYPTQQEKRELLIKTGLTKIQLSNWFINVRRRKIFSDYYTLVNSIPNDNANNTPVERVQNVSAYHNTLSATNNTMYDATST------------CSTDYELSKRFAHAPVTRRKKLIDRLEELKKLSNPDMN---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : .. . :: . :: . :. * . . . . . . . .: :... . . .. : . . :* :::. ...: : . .:*. *** :..::..** :*: :**** :**::: :*.** :*:.*****.*** : . . : . : : : .. ", "identical_positions": 28, "similar_positions": 77, "identity": "6.31%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020123-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P47752-1", "uniprot_id": "S1PR2_RAT", "id": "P47752-1", "name": "Sphingosine 1-phosphate receptor 2", "aln": "--------------MGGLYSEYLNPEKVQEHYNYTKETLDMQETP---SRKVASAF---IIILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGPVTLSLTPLQWFAREGSAFITLSASVFSLLAIAIERQVAIAKVKLYGSDKSCRMLMLIGASWLISLILGGLPILGWNCLDHLEACSTVLPLYAKHYVLCVVTIFSVILLAIVALYVRIYFVVRSSHADVAGPQTLALLKTVTIVLGVFIICWLPAFSILLLDSTCPVRACPVLYKAHYFFAFATLNSLLNPVIYTWRSRDLRREVLRPLLCWRQGKGATGRR-GGNPGHRLLPLRSSSSLERG---LHMPTSPTFLEGNTVV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52592-1", "uniprot_id": "S1PR2_MOUSE", "id": "P52592-1", "name": "Sphingosine 1-phosphate receptor 2", "aln": "--------------MGGLYSEYLNPEKVLEHYNYTKETLDMQETT---SRKVASAF---IIILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGHVTLSLTPVQWFAREGSAFITLSASVFSLLAIAIERQVALAKVKLYGSDKSCRMLMLIGASWLISLILGGLPILGWNCLNQLEACSTVLPLYAKHYVLCVVTIFSVILLAIVALYVRIYFVVRSSHADVAGPQTLALLKTVTIVLGVFIICWLPAFSILLLDSTCPVRACPVLYKAHYFFAFATLNSLLNPVIYTWRSRDLRREVLRPLQCWRRGKGVTGRR-GGNPGHRLLPLRSSSSLERG---MHMPTSPTFLEGNTVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95136-1", "uniprot_id": "S1PR2_HUMAN", "id": "O95136-1", "name": "Sphingosine 1-phosphate receptor 2", "aln": "--------------MGSLYSEYLNPNKVQEHYNYTKETLETQETT---SRQVASAF---IVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERG---MHMPTSPTFLEGNTVV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I8K8-1", "uniprot_id": "S1PR2_DANRE", "id": "Q9I8K8-1", "name": "Sphingosine 1-phosphate receptor 2", "aln": "MTTCRLFAGFCQAVTMSKYSQYFNKTLIQVHYLTAKEMTAEELRDRIESKQSLSSLNILFVVICSIIILENLLVLIAVFRNKKFHSAMFFFIGNLAFSDLLAGSAYIANIFLSGPRTFHLTPVQWFIREGTAFIALSASVFSLLAIAIERYIAITKVKVYGSNKTCRMFLLIGACWVMSILLGGLPIIGWNCINNLDDCSAVLPLNTRYYIRFVVTIFSIILLSIVILYVRIYLIVRTSHQEATNSPAYALLKTVTIVLGVFIICWLPAFTILLLDTSCKMKQCPILNNAGIFFSFATLNSALNPLIYTLRSKDMRKEFLRVLCCW--GLLNCGRP----PHRCMVPLKSSSSMEHCTNKHEHQSIPIMQDCTTCV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **:*:* : ** :** : *:: *:: ::::*. *::********* **.******::*:**** ****** *::** :*** *: ***:*** ***:***:*************** :*::***:***:*:***::****.*::*::******:****:.:*: **:**** :::*: ******:***:** ****** :**:** : : . : **************:******:***** :* :: **:* :* **:.:**** ***:*** **:*:*:*.** * ** * ** * : ::**:****:*: . : * : : .* *", "identical_positions": 196, "similar_positions": 85, "identity": "52.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020125-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P19490-1", "uniprot_id": "GRIA1_RAT", "id": "P19490-1", "name": "Glutamate receptor 1", "aln": "------MPYIFAFFCTGFLGAVVGAN---------------FPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPP-----KLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSN------QFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLD--TAAEKNWQVTAVN--ILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNG-IGYHYILANLGFMDIDLNKFKESGAN-VTGFQLVNYTDTIPARIMQQWRTSDSRDHTRVDWKRPK-------YTSALTYDGVKVMAEAFQSLRRQRIDISR------------------------------------------------------RGNAGDCLANP--AVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKH-DGIRKIGYWNEDDKFVPAATDAQAGG-------DNSSVQNRTYIVTTILEDPYVMLKKN--ANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDP-DTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQT----------TSDQ------------------------------------------------SNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLP------RNSGAGASGGGGSGENGRVVSQDFPKSMQSIPCMSHSSGMPLGATGL------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23818-1", "uniprot_id": "GRIA1_MOUSE", "id": "P23818-1", "name": "Glutamate receptor 1", "aln": "------MPYIFAFFCTGFLGAVVGAN---------------FPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPP-----KLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSN------QFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLD--TAAEKNWQVTAVN--ILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNG-IGYHYILANLGFMDIDLNKFKESGAN-VTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPK-------YTSALTYDGVKVMAEAFQSLRRQRIDISR------------------------------------------------------RGNAGDCLANP--AVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKH-DGIRKIGYWNEDDKFVPAATDAQAGG-------DNSSVQNRTYIVTTILEDPYVMLKKN--ANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDP-DTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQT----------TSDQ------------------------------------------------SNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLP------RNSGAGASGGSGSGENGRVVSQDFPKSMQSIPCMSHSSGMPLGATGL------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42261-1", "uniprot_id": "GRIA1_HUMAN", "id": "P42261-1", "name": "Glutamate receptor 1", "aln": "------MQHIFAFFCTGFLGAVVGAN---------------FPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPP-----KLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSN------QFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLD--TAAEKNWQVTAVN--ILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNG-IGYHYILANLGFMDIDLNKFKESGAN-VTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPK-------YTSALTYDGVKVMAEAFQSLRRQRIDISR------------------------------------------------------RGNAGDCLANP--AVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKH-DGIRKIGYWNEDDKFVPAATDAQAGG-------DNSSVQNRTYIVTTILEDPYVMLKKN--ANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDP-DTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQT----------TSDQ------------------------------------------------SNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLP------RNSGAGASSG-GSGENGRVVSHDFPKSMQSIPCMSHSSGMPLGATGL------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F1V8-1", "uniprot_id": "E7F1V8_DANRE", "id": "E7F1V8-1", "name": "", "aln": "------MWQSFVLLLTGLLGLCSCSS---------------FPSNINIGGLFP-TDSHEYDVFRFALSQHNDVP-----KLVPQVDMVDTGSSFAMTYAFCSQFSKGVYAIIGLYDRKTMNMLMSFCGALHVCFVTPSFPIDTNN------QFVIQLRPELQDALIALVEHYKWNKFVYMYSSDSGLTVLQKILD--TAAEKTWQVTSIN--FDTLTEAAFLKAIQDLDNKKEFKIILDCELERLNSILNLIAAQKKNL-KNYHYILANLGFLDLNLTEFRKGGAN-VTGFQLMNYTNPTVSRTIQDWLEFDSKD-LKSPKRRLK-------YTGALTYDGVTVMATAFQNLRKQRIDISR------------------------------------------------------RGNAGECLANP--PAPWGQGIDIQRALQQVQFEGLTGHVQFNDKGHRTNFTVSVMEFGP-SGPKKVGYWNQREKYVSTATYSNMLN-------ETFGLQNRTYVVTTILEAPYVMLKKN--HEQLVGNDKYEGYCVELAAEIAKHVGYSYRLELVGDGKYGARDA-ETMMWNGMVGELVYGKADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPTKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHADDEEETADQQ----------NQNQPPSPEPNQSPNQS---------------------QNQREEKQEKQPEHTNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDGGSTKEFFRRSKIAVFEKMWSYMKSAEPTVFVKTTDEGVVRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRIPVNLAVLKLNEQAVLDKLKNKWWYDKGECGSKDSARKDKTSALSLSNVAGVFYILIGGLGLAMLVALVEFCYKSRIESRRMK-------QIIDAAMLSSTLT------RMGSG--------GENGRVMAHDFPKGAQTLPCMGQAAAMGLSTTGM------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03445-1", "uniprot_id": "GLR1_DROME", "id": "Q03445-1", "name": "Glutamate receptor 1", "aln": "MHSRLKFLAYLHFICASSIFWPEFSSAQQQ------QQTVSLTEKIPLGAIFEQGTDDVQSAFKYAMLNHNLNVSSRRFELQAYVDVINTADAFKLSRLICNQFSRGVYSMLGAVSPDSFDTLHSYSNTFQMPFVTPWFPEKVLAPSSGLLDFAISMRPDYHQAIIDTIQYYGWQSIIYLYDSHDGLLRLQQIYQELKPGNETFRVQMVKRIANVTMAIEFLHTLEDLGRFSKKRIVLDCPAEMAKEIIVQHVRDIKLGRRTYHYLLSGLVMDNHWPSDVVEFGAINITGFRIVDSNRRAVRDFHDSRKRLEPSGQSQSQNAGGPNSLPAISAQAALMYDAVFVLVEAFNRILRKKPDQFRSNHLQRRS-------HGGSSSS-----SATG--------------------TNESSALLDCNTSKGWVTPWEQGEKISRVLRKVEIDGLSGEIRFDEDGRRINYTLHVVEMSVNSTLQQVAEWRDDAGLLPLHSHNYASSSRSASASTGDYDRNHTYIVSSLLEEPYLSLKQYTYGESLVGNDRFEGYCKDLADMLAAQLGIKYEIRLVQDGNYGAENQYAPGGWDGMVGELIRKEADIAISAMTITAERERVIDFSKPFMTLGISIMIKKPVKQTPGVFSFLNPLSQEIWISVILSYVGVSFVLYFVTRFPPYEWRIVRRPQADS------------TAQQPPGIIGGATLSEP-----------------QAHVPPVPP----------NEFTMLNSFWYSLAAFMQQGCDITPPSIAGRIAAAVWWFFTIILISSYTANLAAFLTVERMVAPIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYMNANQ-HHSVHTYDEGIRRVRQSKGKYALLVESPKNEYVNARPPCDTMKVGRNIDTKGFGVATPIGSPLRKRLNEAVLTLKENGELLRIRNKWWFDKTECN-LDQETSTPN-ELSLSNVAGIYYILIGGLLLAVIVAIMEFFCRNKTPQLKSPGS-----NGSAGGVPG----------MLASS---------TYQRDSLSDAIMHSQAKLAMQASSEYDERLVGVELASNVRYQYSM------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PHV5-1", "uniprot_id": "M9PHV5_DROME", "id": "M9PHV5-1", "name": "", "aln": "----MRFGLKLSCLWPSFLLWLTWSSGGGGGSGVGVSAQPSLTEKIPLGAIFEQGTDEVQSAFKYAMLNHNLNVSSRRFELQAYVDVINTADAFKLSRLICNQFSRGVYSMLGAVSPDSFDTLHSYSNTFQMPFVTPWFPEKVLTPSSGFLDFALSMRPDYHQAIIDTIQFYGWRKIIYLYDSHDGLLRLQQIYQGLRPGNESFQVELVKRISNVSMAIEFLHTLEQIGRFENKHIVLDCPTEMAKQILIQHVRDLRLGRRTYHYLLSGLVMDDRWESEIIEFGAINITGFRIVDTNRRLVREFYDSWKRLDP---QMSVGAGRE----SISAQAALMYDAVFVLVEAFNKILRKKPDQFR-NNVQRRSQTLMVAQAAASTSSDGYNYSASGGGGGNGGAGGGFAGSDSGGSGGMASRALDCNTAKGWVNAWEHGDKISRYLRKVEIEGLTGDIKFNDDGRRVNYTLHVVEMTVNSAMVKVAEWNDDAGLQPLNAKYVRLR------PHVEFEKNRTYIVTTVLEEPYIMLKQVAFGEKLHGNNRFEGYCKDLADLLAKELGINYELRLVKDGNYGSEKSSAHGGWDGMVGELVRKEADIAIAAMTITAERERVIDFSKPFMSLGISIMIKKPVKQTPGVFSFMNPLSQEIWVSVIFSYIGVSIVLFFVSRFSPHEWRLVQQQPQQSQSPDPHAHHEQLANQQPPGIIGGAPLPAPPGPPTPGAQTAAGAAALQAALSAGSPGSGGSSSAVVNEFSVWNSFWFSLAAFMQQGCDLSPRSVSGRIAAASWFFFTLILISSYTANLAAFLTVERMVTPINSPEDLAMQTEVQYGTLLHGSTWDFFRRSQIGLHNKMWEYMNSRK-HVFVPTYDEGIKRVRNSKGKYALLVESPKNEYVNAREPCDTMKVGRNLDTKGFGIATPLGSALKDPINLAVLTLKENGELIKLRNKWWYEKAECS-THKDGETSHSELSLSNVAGIFYILIGGLLVSVFVAILEYCFRSRDSRSASSGSGMGLGMGLGGGMSGGSLGKANGSMMLGPSSAVPGGMPSSHQRSTLTD-TMHAKAKLTIQASRDYDNGRVGYLNCASLQYYPPAQLSATPPDAGDSLHMNAHGQVXHEHAQESRLXRTPCAPTIRRIMANSRQETEKMMGGGHGGTVTVSVPATCSSSMNGSHEGSLALSPSSGSATLMRHSPDINQHPYGK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : .. : :. :..:* :*.:* .. .*::*: : . :* . :*::: ..:* :: :*.***:***:::* . :.: * *:..:::: *:** ** .. :*.:.:**: ::*:* ::.* *..::*:*.:. ** **:: : ..::.::* :: . : :::: . .: :::** * : *: : ***:*:.* : : ... : ** :***:::: . :. :. .** **.* *:. **: : ::: * * . :* : .* :* .*.* *::*.::**:*.::*::.*:* *:*: *:*: . ::. *.: . : :*:**:*:::** **: **: :.: **:::**** :** :* .:* .*.:.:* **:**:.. *:******: .**:*::.:*** **.*********:********** *..******::**: ***:.::::*:***.**::*:**.*:**: . :* *** : **:*:**.********::* *::***... *:***:*:******************:**::.***: **:: **** *** :*****:*.:.:*** **:: : * * :**: ***:****** *:**. ***:: * ******** *:*:**:*:*** **.*: :* ***.*.*:. * :::.***::* **. . ********::******* ::::**::*: :.: .: . . * * :: : : .* ", "identical_positions": 306, "similar_positions": 296, "identity": "25.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020125-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P19491-1", "uniprot_id": "GRIA2_RAT", "id": "P19491-1", "name": "Glutamate receptor 2", "aln": "----MQKIMHISVLLSPVLWGLIFG---------------VSSNSIQIGGLFPRGADQEYSAFRVGMVQF----STSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSF------PTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVIT-IGKHVKGYHYIIANLGFTDG-DLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEE---KEYPGAHTAT----IKYTSALTYDAVQVMTEAFRNLRKQR------IEISRRG--------------------NAG----------------------------DCLANP--AVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTN-GPRKIGYWSEVDKMVVTLTELPSGNDTSG-------LENKTVVVTTILESPYVMMKKN--HEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTK-IWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH---------------------TEEFEDGRETQSSESTN-------------------------------------EFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKV---------------------------------------AKNPQNINPSSSQNSQNFATYKEGYNVYGIESVKI----------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23819-1", "uniprot_id": "GRIA2_MOUSE", "id": "P23819-1", "name": "Glutamate receptor 2", "aln": "----MQKIMHISVLLSPVLWGLIFG---------------VSSNSIQIGGLFPRGADQEYSAFRVGMVQF----STSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSF------PTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVIT-IGKHVKGYHYIIANLGFTDG-DLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEE---KEYPGAHTAT----IKYTSALTYDAVQVMTEAFRNLRKQR------IEISRRG--------------------NAG----------------------------DCLANP--AVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTN-GPRKIGYWSEVDKMVVTLTELPSGNDTSG-------LENKTVVVTTILESPYVMMKKN--HEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTK-IWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH---------------------TEEFEDGRETQSSESTN-------------------------------------EFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKV---------------------------------------AKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI----------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42262-1", "uniprot_id": "GRIA2_HUMAN", "id": "P42262-1", "name": "Glutamate receptor 2", "aln": "----MQKIMHISVLLSPVLWGLIFG---------------VSSNSIQIGGLFPRGADQEYSAFRVGMVQF----STSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSF------PTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVIT-IGKHVKGYHYIIANLGFTDG-DLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEE---KEYPGAHTTT----IKYTSALTYDAVQVMTEAFRNLRKQR------IEISRRG--------------------NAG----------------------------DCLANP--AVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTN-GPRKIGYWSEVDKMVVTLTELPSGNDTSG-------LENKTVVVTTILESPYVMMKKN--HEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTK-IWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH---------------------TEEFEDGRETQSSESTN-------------------------------------EFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKV---------------------------------------AKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI----------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BI34-1", "uniprot_id": "A0A8M2BI34_DANRE", "id": "A0A8M2BI34-1", "name": "Glutamate receptor", "aln": "--------MILSGLLLPALWGLALG---------------GSP-SVQIGGLFPRGADQEYSAFRIGMVQF----GTAEFRLTPHIDNLEVANSFAITNCFCSQFSRGVYAIFGFYDKKSVNTITSFCETLHVSFITPSF------PADGLNQFVLQMRPDIKGPLISLVEYYKWEKFAYLYDSDRGLSTLQAVLDTAAERKWQVTAINVGNLKDEWKDEAYRSLFQDLENKNERRVILDCEQDKVKDIMEQVIT-IGRHVKGYHYIIANFGFVDG-DLSKIQYGGANVSGFQIVDFDDPLVAKFDQRWEALEE---KEYPGADSR-----IRYTSALTYDAVQVMTEAFRFLHKQR------IDISRRG--------------------NNG----------------------------DCLANP--AVPWAQGVEIERALKQVRVDGLTGNIQFDQYGRRVNYTVNVMELKNS-GPVKIGYWNEMDKMAVTKSDLFP-NDTMG-------MENKTVIVTTILEAPYVMLKKN--AELFTDNERYEGYCVDLAAEIAKHCGFKYQLRIVADGKYGARDAETK-IWNGMVGELVYGKADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH---------------------TEEFEDG-QLGPSESTN-------------------------------------EFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDAGSTKEFFRRSKIALFDKMWQYMKSAEPSVFVKNTVEGVLRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALVEFCYKSRAEAKRMKMTFTD--------------------------------AMRSKARLSITGSTGENGR-VLTPDFSKAVHAVPYLRPGMAMPLSVSELS----------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03445-1", "uniprot_id": "GLR1_DROME", "id": "Q03445-1", "name": "Glutamate receptor 1", "aln": "MHSRLKFLAYLHFICASSIFWPEFSSAQQQ------QQTVSLTEKIPLGAIFEQGTDDVQSAFKYAMLNHNLNVSSRRFELQAYVDVINTADAFKLSRLICNQFSRGVYSMLGAVSPDSFDTLHSYSNTFQMPFVTPWFPEKVLAPSSGLLDFAISMRPDYHQAIIDTIQYYGWQSIIYLYDSHDGLLRLQQIYQELKPGNETFRVQMVKRIANVTMAIEFLHTLEDLGRFSKKRIVLDCPAEMAKEIIVQHVRDIKLGRRTYHYLLSGLVMDNHWPSDVVEFGAINITGFRIVDSNRRAVRDFHDSRKRLEPSGQSQSQNAGGPNSLPAISAQAALMYDAVFVLVEAFNRILRKKPDQFRSNHLQRRS-------HGGSSSS-----SATG--------------------TNESSALLDCNTSKGWVTPWEQGEKISRVLRKVEIDGLSGEIRFDEDGRRINYTLHVVEMSVNSTLQQVAEWRDDAGLLPLHSHNYASSSRSASASTGDYDRNHTYIVSSLLEEPYLSLKQYTYGESLVGNDRFEGYCKDLADMLAAQLGIKYEIRLVQDGNYGAENQYAPGGWDGMVGELIRKEADIAISAMTITAERERVIDFSKPFMTLGISIMIKKPVKQTPGVFSFLNPLSQEIWISVILSYVGVSFVLYFVTRFPPYEWRIVRRPQADS------------TAQQPPGIIGGATLSEP-----------------QAHVPPVPP----------NEFTMLNSFWYSLAAFMQQGCDITPPSIAGRIAAAVWWFFTIILISSYTANLAAFLTVERMVAPIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYMNANQ-HHSVHTYDEGIRRVRQSKGKYALLVESPKNEYVNARPPCDTMKVGRNIDTKGFGVATPIGSPLRKRLNEAVLTLKENGELLRIRNKWWFDKTECNLDQ-ETSTPN-ELSLSNVAGIYYILIGGLLLAVIVAIMEFFCRNKTPQLKSPGS-----NGSAGGVPG----------MLASS---------TYQRDSLSDAIMHSQAKLAMQASSEYDERLVGVELASNVRYQYSM------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PHV5-1", "uniprot_id": "M9PHV5_DROME", "id": "M9PHV5-1", "name": "", "aln": "----MRFGLKLSCLWPSFLLWLTWSSGGGGGSGVGVSAQPSLTEKIPLGAIFEQGTDEVQSAFKYAMLNHNLNVSSRRFELQAYVDVINTADAFKLSRLICNQFSRGVYSMLGAVSPDSFDTLHSYSNTFQMPFVTPWFPEKVLTPSSGFLDFALSMRPDYHQAIIDTIQFYGWRKIIYLYDSHDGLLRLQQIYQGLRPGNESFQVELVKRISNVSMAIEFLHTLEQIGRFENKHIVLDCPTEMAKQILIQHVRDLRLGRRTYHYLLSGLVMDDRWESEIIEFGAINITGFRIVDTNRRLVREFYDSWKRLDP---QMSVGAGRE----SISAQAALMYDAVFVLVEAFNKILRKKPDQFR-NNVQRRSQTLMVAQAAASTSSDGYNYSASGGGGGNGGAGGGFAGSDSGGSGGMASRALDCNTAKGWVNAWEHGDKISRYLRKVEIEGLTGDIKFNDDGRRVNYTLHVVEMTVNSAMVKVAEWNDDAGLQPLNAKYVRLR------PHVEFEKNRTYIVTTVLEEPYIMLKQVAFGEKLHGNNRFEGYCKDLADLLAKELGINYELRLVKDGNYGSEKSSAHGGWDGMVGELVRKEADIAIAAMTITAERERVIDFSKPFMSLGISIMIKKPVKQTPGVFSFMNPLSQEIWVSVIFSYIGVSIVLFFVSRFSPHEWRLVQQQPQQSQSPDPHAHHEQLANQQPPGIIGGAPLPAPPGPPTPGAQTAAGAAALQAALSAGSPGSGGSSSAVVNEFSVWNSFWFSLAAFMQQGCDLSPRSVSGRIAAASWFFFTLILISSYTANLAAFLTVERMVTPINSPEDLAMQTEVQYGTLLHGSTWDFFRRSQIGLHNKMWEYMNSRK-HVFVPTYDEGIKRVRNSKGKYALLVESPKNEYVNAREPCDTMKVGRNLDTKGFGIATPLGSALKDPINLAVLTLKENGELIKLRNKWWYEKAECSTHK-DGETSHSELSLSNVAGIFYILIGGLLVSVFVAILEYCFRSRDSRSASSGSGMGLGMGLGGGMSGGSLGKANGSMMLGPSSAVPGGMPSSHQRSTLTD-TMHAKAKLTIQASRDYDNGRVGYLNCASLQYYPPAQLSATPPDAGDSLHMNAHGQVXHEHAQESRLXRTPCAPTIRRIMANSRQETEKMMGGGHGGTVTVSVPATCSSSMNGSHEGSLALSPSSGSATLMRHSPDINQHPYGK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 326, "similar_positions": 289, "identity": "27.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020125-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P42262-1", "uniprot_id": "GRIA2_HUMAN", "id": "P42262-1", "name": "Glutamate receptor 2", "aln": "MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDS-----------------------------------------------KEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKV-------AKNAQNINPSSSQN----SQNF--ATYKEGYNVYGIES-VKI----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23819-1", "uniprot_id": "GRIA2_MOUSE", "id": "P23819-1", "name": "Glutamate receptor 2", "aln": "MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDS-----------------------------------------------KEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKV-------AKNAQNINPSSSQN----SQNF--ATYKEGYNVYGIES-VKI----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32T5C3-1", "uniprot_id": "A0AB32T5C3_DANRE", "id": "A0AB32T5C3-1", "name": "Glutamate receptor", "aln": "MQQLKNLSICLIALLLGMTTGGSP-SVQIGGLFPRGADQEYSAFRIGMVQFGTAEFRLTPHIDNLEVANSFAVTNCFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPLDGNQQFIIQMRPDIKGPLLSLIEYYKWDKFAYLYDSDRGLTTLQVVLDTAAEKKWQVTAINVGNMKDERKDEAYRSLFQDLENKKERRVILDCEQDKVKDIMEQVITIGRHVKGYHYIIANLGFVDGDLSKIQYGGANVSGFQIVDFDDPLVSKFDQRWEALEEKEYPGADS-KIRYTSALTYDAVQVMTEAFRYLHKQRIDISRRANNGDCLANPAVPWAQGVEIERALKQVRVDGLTGNIQFDQYGKRVNYTVNVMELKSNGAVKIGYWNEVDKMVVTKSDLFP-NDTMGLENKTVIVTTILEAPYVMLKKNADLFMDNERYEGYCVDLAAEIAKHCGFKYQLKIVGDGKYGARDAETKIWNGMVGELVYGKADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEYEDG-QIQTNESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIALFDKMWTYMKGAEPSVFVKTTAEGVMRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKVSPREQSDGTPVNLAVLKLSEQGTLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALVEFCYKSRAEAKRMKVTFSDAMRSKARLSVTGSTGENGRVMSPEFPKAVHAVPFVRPGVGMNVSLTDLS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:: ::*: * .:* *: * *. *:******************:*****.*:*********************.***************************************** **.: *:******:**.********:**************:***.***:***************:::::*** ********* ***********:***:**::******:**************.**** ***:************:**.***** :**.:*********.: .*:****************** *:****:****.* ***********.************:*:**:***:*** ***:***:*:****:**. *****.******** ::* . *** *******:******:****:*** ::: .***********************:*.************:*******************:*******************************************************************************:*** : *:.********************:*****************************************************:*************************:********:.*******:****** *************************************************** ************************************* *******************************:*************** :* .:. *:.:* * :* *.: : *: *.: ", "identical_positions": 744, "similar_positions": 97, "identity": "78.48%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020125-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P42263-1", "uniprot_id": "GRIA3_HUMAN", "id": "P42263-1", "name": "Glutamate receptor 3", "aln": "-MARQKKMGQSVLRAVFFLVLGLLGHSHGG-----------FPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSF------PTDADVQFVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNN---WQVTARSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKH-SRGYHYMLANLGFTD-ILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNA-------PLKYTSALTHDAILVIAEAFRYLRRQRVDVSR-----RGS---------------------AG----------------------------DCLANP--AVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKV-SGSRKAGYWNEYERFVPFSDQQISNDS--------ASSENRTIVVTTILESPYVMYKKN--HEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDP-ETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRD------------PQSPP----------------------------------DPP----------NEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDS------------------------------------------------------KDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAES----------------------------------------------KRMKLTKNTQNFKPAPATNT-QNYATYREGYNVYGTESVKI--------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19492-1", "uniprot_id": "GRIA3_RAT", "id": "P19492-1", "name": "Glutamate receptor 3", "aln": "-------MGQSVLRAVFFLVLGLLGHSHGG-----------FPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSF------PTDADVQFVIQMRPALKGAILSLLSYYKWEKFVYLYDTERGFSVLQAIMEAAVQNN---WQVTARSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKH-SRGYHYMLANLGFTD-ILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNA-------PLKYTSALTHDAILVIAEAFRYLRRQRVDVSR-----RGS---------------------AG----------------------------DCLANP--AVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKV-SGSRKAGYWNEYERFVPFSDQQISNDS--------SSSENRTIVVTTILESPYVMYKKN--HEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDP-ETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRD------------PQSPP----------------------------------DPP----------NEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDS------------------------------------------------------KDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAES----------------------------------------------KRMKLTKNTQNFKPAPATNT-QNYATYREGYNVYGTESVKI--------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2W9-1", "uniprot_id": "GRIA3_MOUSE", "id": "Q9Z2W9-1", "name": "Glutamate receptor 3", "aln": "-------MGQSVLRAVFFLVLGLLGHSHGG-----------FPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSF------PTDADVQFVIQMRPALKGAILSLLGYYKWEKFVYLYDTERGFSILQAIMEAAVQNN---WQVTARSVGNIKDIQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKH-SRGYHYMLANLGFTD-IVLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNA-------PLKYTSALTHDAILVIAEAFRYLRRQRVDVSR-----RGS---------------------AG----------------------------DCLANP--AVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKV-SGSRKAGYWNEYERFVPFSDQQISNDS--------SSSENRTIVVTTILESPYVMYKKN--HEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDP-ETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRD------------PQSPP----------------------------------DPP----------NEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAKDSGS------------------------------------------------------KDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAES----------------------------------------------KRMKLTKNTQNFKPAPATNT-QNYATYREGYNVYGTESVKI--------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58JH93-1", "uniprot_id": "A0AC58JH93_DANRE", "id": "A0AC58JH93-1", "name": "Glutamate receptor", "aln": "-------MRRRAHASVLLLPWLVL-QTQAG-----------FPNQINIGGLFMRSTVQEHSAFRFAVQLYNTNQNITEKPFHLNYNVDNLESSNSFSVTHAFCSQFSRGVYAIFGFYDRRSMNTLTSFCGALHTSFITPSF------PTDTDVQFVLQMRPSLRGALLSLLAHYKWEKFVYLYDTDRGFSILQAIMESAVMNN---WQVTARSVGNIVDPLEYRRIIEEMDRRQEKRFLIDCEVERINSILEQVVIAGKN-SRGYHYILANLGFTN-MSLDKVFSGGANITGFQIINPDSPIVQQFLQRWERLDEREFPESRSS-------PLKYTSALTHDAILVIAEAFRYLRRQRVDISR-----RGS---------------------AG----------------------------DCLANP--AVPWSQGIDIERALKMVQVQGMTGNIQFDSFGRRSNYTVDVYEMKP-GGARKIGYWNEFEKFVYIVEQQVTNES--------SSVENRTIVVTTIMEAPYVMYKRN--YMQLEGNDRYEGYCVDLASEIAKHVGIKYKLSIVADGKYGARDP-ETKTWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLDDN-EETKD------------PQTPP----------------------------------DPP----------NDFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFVKTTPDGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRSAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKHKARCPTVSLWLTDIRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGTKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMTVALVEFCYKSHQET----------------------------------------------KRLKLAKNAQNFKPAPPSTA-QSFTTYREGYNVYGTESVKI--------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03445-1", "uniprot_id": "GLR1_DROME", "id": "Q03445-1", "name": "Glutamate receptor 1", "aln": "MHSRLKFLAYLHFICASSIFWPEFSSAQQQ------QQTVSLTEKIPLGAIFEQGTDDVQSAFKYAMLNHN--LNVSSRRFELQAYVDVINTADAFKLSRLICNQFSRGVYSMLGAVSPDSFDTLHSYSNTFQMPFVTPWFPEKVLAPSSGLLDFAISMRPDYHQAIIDTIQYYGWQSIIYLYDSHDGLLRLQQIYQELKPGNETFRVQMVKRIANVTMAIEFLHTLEDLGRFSKKRIVLDCPAEMAKEIIVQHVRDIKLGRRTYHYLLSGLVMDNHWPSDVVEFGAINITGFRIVDSNRRAVRDFHDSRKRLEPSGQSQSQNAGGPNSLPAISAQAALMYDAVFVLVEAFNRILRKKPDQFRSNHLQRRS-------HGGSSSS-----SATG--------------------TNESSALLDCNTSKGWVTPWEQGEKISRVLRKVEIDGLSGEIRFDEDGRRINYTLHVVEMSVNSTLQQVAEWRDDAGLLPLHSHNYASSSRSASASTGDYDRNHTYIVSSLLEEPYLSLKQYTYGESLVGNDRFEGYCKDLADMLAAQLGIKYEIRLVQDGNYGAENQYAPGGWDGMVGELIRKEADIAISAMTITAERERVIDFSKPFMTLGISIMIKKPVKQTPGVFSFLNPLSQEIWISVILSYVGVSFVLYFVTRFPPYEWRIVRRPQADS------------TAQQPPGIIGGATLSEP-----------------QAHVPPVPP----------NEFTMLNSFWYSLAAFMQQGCDITPPSIAGRIAAAVWWFFTIILISSYTANLAAFLTVERMVAPIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYMNANQ-HHSVHTYDEGIRRVRQSKGKYALLVESPKNEYVNARPPCDTMKVGRNIDTKGFGVATPIGSPLRKRLNEAVLTLKENGELLRIRNKWWFDKTECNLDQETS-------------------------------------------------------TPN-ELSLSNVAGIYYILIGGLLLAVIVAIMEFFCRNKTPQLKSPGS-----NGSAGGVPG----------MLASS---------TYQRDSLSDAIMHSQAKLAMQASSEYDERLVGVELASNVRYQYSM------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PHV5-1", "uniprot_id": "M9PHV5_DROME", "id": "M9PHV5-1", "name": "", "aln": "----MRFGLKLSCLWPSFLLWLTWSSGGGGGSGVGVSAQPSLTEKIPLGAIFEQGTDEVQSAFKYAMLNHN--LNVSSRRFELQAYVDVINTADAFKLSRLICNQFSRGVYSMLGAVSPDSFDTLHSYSNTFQMPFVTPWFPEKVLTPSSGFLDFALSMRPDYHQAIIDTIQFYGWRKIIYLYDSHDGLLRLQQIYQGLRPGNESFQVELVKRISNVSMAIEFLHTLEQIGRFENKHIVLDCPTEMAKQILIQHVRDLRLGRRTYHYLLSGLVMDDRWESEIIEFGAINITGFRIVDTNRRLVREFYDSWKRLDP---QMSVGAGRE----SISAQAALMYDAVFVLVEAFNKILRKKPDQFR-NNVQRRSQTLMVAQAAASTSSDGYNYSASGGGGGNGGAGGGFAGSDSGGSGGMASRALDCNTAKGWVNAWEHGDKISRYLRKVEIEGLTGDIKFNDDGRRVNYTLHVVEMTVNSAMVKVAEWNDDAGLQPLNAKYVRLR------PHVEFEKNRTYIVTTVLEEPYIMLKQVAFGEKLHGNNRFEGYCKDLADLLAKELGINYELRLVKDGNYGSEKSSAHGGWDGMVGELVRKEADIAIAAMTITAERERVIDFSKPFMSLGISIMIKKPVKQTPGVFSFMNPLSQEIWVSVIFSYIGVSIVLFFVSRFSPHEWRLVQQQPQQSQSPDPHAHHEQLANQQPPGIIGGAPLPAPPGPPTPGAQTAAGAAALQAALSAGSPGSGGSSSAVVNEFSVWNSFWFSLAAFMQQGCDLSPRSVSGRIAAASWFFFTLILISSYTANLAAFLTVERMVTPINSPEDLAMQTEVQYGTLLHGSTWDFFRRSQIGLHNKMWEYMNSRK-HVFVPTYDEGIKRVRNSKGKYALLVESPKNEYVNAREPCDTMKVGRNLDTKGFGIATPLGSALKDPINLAVLTLKENGELIKLRNKWWYEKAECSTHKDGE-------------------------------------------------------TSHSELSLSNVAGIFYILIGGLLVSVFVAILEYCFRSRDSRSASSGSGMGLGMGLGGGMSGGSLGKANGSMMLGPSSAVPGGMPSSHQRSTLTD-TMHAKAKLTIQASRDYDNGRVGYLNCASLQYYPPAQLSATPPDAGDSLHMNAHGQVXHEHAQESRLXRTPCAPTIRRIMANSRQETEKMMGGGHGGTVTVSVPATCSSSMNGSHEGSLALSPSSGSATLMRHSPDINQHPYGK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 341, "similar_positions": 285, "identity": "27.08%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020125-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48058-1", "uniprot_id": "GRIA4_HUMAN", "id": "P48058-1", "name": "Glutamate receptor 4", "aln": "----MRIISRQIVLLFSGFWGLAMG---------------AFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSF------PTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVS-VGKHVKGYHYIIANLGFKD-ISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQ-----REYPGSET---PPKYTSALTYDGVLVMAETFRSLRRQKIDISR------------------------------------------------------RGNAGDCLANP--AAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRVNYTMDVFELKS-TGPRKVGYWNDMDKLVLIQDVPTLGNDT-------AAIENRTVVVTTIMESPYVMYKKN--HEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDA-DTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGP-----------SDQPP-----------------------------------------------NEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLRTPVNLAVLKLSEAGVLDKLKNKWWYDKGECGPKDSGSKDKTS-ALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKLT-------FSEAIRN-------------------------KARLSITGSVGENGRVLTPDCPKAVHTG-TAIRQSSGLAVIASDLP----------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z2W8-1", "uniprot_id": "GRIA4_MOUSE", "id": "Q9Z2W8-1", "name": "Glutamate receptor 4", "aln": "----MRIICRQIVLLFSGFWGLAMG---------------AFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSF------PTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVS-VGKHVKGYHYIIANLGFKD-ISLERFIHGGANVTGFQLVDFNTPMVTKLMDRWKKLDQ-----REYPGSET---PPKYTSALTYDGVLVMAETFRSLRRQKIDISR------------------------------------------------------RGNAGDCLANP--AAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRVNYTMDVFELKS-TGPRKVGYWNDMDKLVLIQDAPTLGNDT-------AAIENRTVVVTTIMESPYVMYKKN--HEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDA-DTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGP-----------SDQPP-----------------------------------------------NEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLRTPVNLAVLKLSEAGVLDKLKNKWWYDKGECGPKDSGSKDKTS-ALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKLT-------FSEAIRN-------------------------KARLSITGSVGENGRVLTPDCPKAVHTG-TAIRQSSGLAVIASDLP----------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19493-1", "uniprot_id": "GRIA4_RAT", "id": "P19493-1", "name": "Glutamate receptor 4", "aln": "----MRIICRQIVLLFSGFWGLAMG---------------AFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSF------PTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVS-VGKHVKGYHYIIANLGFKD-ISLERFIHGGANVTGFQLVDFNTPMVTKLMDRWKKLDQ-----REYPGSET---PPKYTSALTYDGVLVMAETFRSLRRQKIDISR------------------------------------------------------RGNAGDCLANP--AAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRVNYTMDVFELKS-TGPRKVGYWNDMDKLVLIQDMPTLGNDT-------AAIENRTVVVTTIMESPYVMYKKN--HEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDA-DTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGP-----------SDQPP-----------------------------------------------NEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTMNEYTEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTS-ALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKLT-------FSEATRN-------------------------KARLSITGSVGENGRVLTPDCPKAVHTG-TAIRQSSGLAVIASDLP----------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M6Z9L8-1", "uniprot_id": "A0A8M6Z9L8_DANRE", "id": "A0A8M6Z9L8-1", "name": "Glutamate receptor", "aln": "---------MRILVLIPLLWGLGEG---------------AFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNATEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLVTPSF------PAEGETQFVLQLRPSIRGALLSLLDHYDWSRFVFLYDTDRGYAVLQAIMEKAGQNGWQVSAICVENFN----DASYRRLLEDLDRRQEKKFVIDLEAERLQNILEQIVS-VGKHVKGYHYIVANLGFKD-ISLERFMHGGANVTGFQLVDFSKPMVIKLMQRWNKLDQ-----REYPGSES---PPRYTSSLTYDGVLVMAEAFRNLRRQKIDISR------------------------------------------------------RGNAGDCLANP--AAPWNQGIDMERTLKQVRIQGLTGNIQFDHYGRRVNYTMDVFELKS-NGPRKIGYWNDLDKLVLVQNELSMGND--------SAMENRTVIVTTIMEGPYVMLKKN--WEMYEGNEQFEGYCVDLASEIAKHIGIKYKISIVPDGKYGARDP-ETKIWNGMVGELVYGKAEIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEEGSDGPP----------SDQPP-----------------------------------------------NEFGIFNSLWFSLGAFMQQGCDFTPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPTVFTKTTAEGVARVRKSKGKYAFLLESTMNEYTEQRKPCDTMKVGGNLDSKGYGVATPKGSQLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKSSQALSLSNVAGVFYILVGGLGLAMLVALVEFCYKSRAEAKKLKLT-------FSEAMRN-------------------------KARLSITGSLGENGRVLTPDCPKAVHSG-PSYRHGPALAVVSSYLP----------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03445-1", "uniprot_id": "GLR1_DROME", "id": "Q03445-1", "name": "Glutamate receptor 1", "aln": "MHSRLKFLAYLHFICASSIFWPEFSSAQQQ------QQTVSLTEKIPLGAIFEQGTDDVQSAFKYAMLNHN--LNVSSRRFELQAYVDVINTADAFKLSRLICNQFSRGVYSMLGAVSPDSFDTLHSYSNTFQMPFVTPWFPEKVLAPSSGLLDFAISMRPDYHQAIIDTIQYYGWQSIIYLYDSHDGLLRLQQIYQELKPGNETFRVQMVKRIANVTMAIEFLHTLEDLGRFSKKRIVLDCPAEMAKEIIVQHVRDIKLGRRTYHYLLSGLVMDNHWPSDVVEFGAINITGFRIVDSNRRAVRDFHDSRKRLEPSGQSQSQNAGGPNSLPAISAQAALMYDAVFVLVEAFNRILRKKPDQFRSNHLQRRS-------HGGSSSS-----SATG--------------------TNESSALLDCNTSKGWVTPWEQGEKISRVLRKVEIDGLSGEIRFDEDGRRINYTLHVVEMSVNSTLQQVAEWRDDAGLLPLHSHNYASSSRSASASTGDYDRNHTYIVSSLLEEPYLSLKQYTYGESLVGNDRFEGYCKDLADMLAAQLGIKYEIRLVQDGNYGAENQYAPGGWDGMVGELIRKEADIAISAMTITAERERVIDFSKPFMTLGISIMIKKPVKQTPGVFSFLNPLSQEIWISVILSYVGVSFVLYFVTRFPPYEWRIVRRPQADS------------TAQQPPGIIGGATLSEP-----------------QAHVPPVPP----------NEFTMLNSFWYSLAAFMQQGCDITPPSIAGRIAAAVWWFFTIILISSYTANLAAFLTVERMVAPIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYMNANQ-HHSVHTYDEGIRRVRQSKGKYALLVESPKNEYVNARPPCDTMKVGRNIDTKGFGVATPIGSPLRKRLNEAVLTLKENGELLRIRNKWWFDKTECNLDQETS--TPN-ELSLSNVAGIYYILIGGLLLAVIVAIMEFFCRNKTPQLKSPGS-----NGSAGGVPG----------MLASS---------TYQRDSLSDAIMHSQAKLAMQASSEYDERLVGVELASNVRYQYSM------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PHV5-1", "uniprot_id": "M9PHV5_DROME", "id": "M9PHV5-1", "name": "", "aln": "----MRFGLKLSCLWPSFLLWLTWSSGGGGGSGVGVSAQPSLTEKIPLGAIFEQGTDEVQSAFKYAMLNHN--LNVSSRRFELQAYVDVINTADAFKLSRLICNQFSRGVYSMLGAVSPDSFDTLHSYSNTFQMPFVTPWFPEKVLTPSSGFLDFALSMRPDYHQAIIDTIQFYGWRKIIYLYDSHDGLLRLQQIYQGLRPGNESFQVELVKRISNVSMAIEFLHTLEQIGRFENKHIVLDCPTEMAKQILIQHVRDLRLGRRTYHYLLSGLVMDDRWESEIIEFGAINITGFRIVDTNRRLVREFYDSWKRLDP---QMSVGAGRE----SISAQAALMYDAVFVLVEAFNKILRKKPDQFR-NNVQRRSQTLMVAQAAASTSSDGYNYSASGGGGGNGGAGGGFAGSDSGGSGGMASRALDCNTAKGWVNAWEHGDKISRYLRKVEIEGLTGDIKFNDDGRRVNYTLHVVEMTVNSAMVKVAEWNDDAGLQPLNAKYVRLR------PHVEFEKNRTYIVTTVLEEPYIMLKQVAFGEKLHGNNRFEGYCKDLADLLAKELGINYELRLVKDGNYGSEKSSAHGGWDGMVGELVRKEADIAIAAMTITAERERVIDFSKPFMSLGISIMIKKPVKQTPGVFSFMNPLSQEIWVSVIFSYIGVSIVLFFVSRFSPHEWRLVQQQPQQSQSPDPHAHHEQLANQQPPGIIGGAPLPAPPGPPTPGAQTAAGAAALQAALSAGSPGSGGSSSAVVNEFSVWNSFWFSLAAFMQQGCDLSPRSVSGRIAAASWFFFTLILISSYTANLAAFLTVERMVTPINSPEDLAMQTEVQYGTLLHGSTWDFFRRSQIGLHNKMWEYMNSRK-HVFVPTYDEGIKRVRNSKGKYALLVESPKNEYVNAREPCDTMKVGRNLDTKGFGIATPLGSALKDPINLAVLTLKENGELIKLRNKWWYEKAECSTHKDGE--TSHSELSLSNVAGIFYILIGGLLVSVFVAILEYCFRSRDSRSASSGSGMGLGMGLGGGMSGGSLGKANGSMMLGPSSAVPGGMPSSHQRSTLTD-TMHAKAKLTIQASRDYDNGRVGYLNCASLQYYPPAQLSATPPDAGDSLHMNAHGQVXHEHAQESRLXRTPCAPTIRRIMANSRQETEKMMGGGHGGTVTVSVPATCSSSMNGSHEGSLALSPSSGSATLMRHSPDINQHPYGK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 333, "similar_positions": 302, "identity": "27.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020129-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q01815-1", "uniprot_id": "CAC1C_MOUSE", "id": "Q01815-1", "name": "Voltage-dependent L-type calcium channel subunit alpha-1C", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVNENTRMYVPEENHQ-----------GSNYGSP----RPAHAN-MNANAAAG-------LAPEHIPTPGAALS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WQAAIDAARQAKLMGSAGNATISTVSSTQRKRQ-------------------------------------------------------------------------------------------------------------------------------------QYG----------------------------------------------------------------------------------------------KPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIII--LLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRN------------------------GWNLLDFIIVVVGLFSAILEQATKADGANALGGKG-------------------------------------------AGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN-QEGIIDVPAEEDPSPCALETGHGRQCQNG--TVCKPGWDG-------------------PKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPEN----EDEGMDEDKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYN--QPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSP----LGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQ-TRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPG---MLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEK-PAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDT-AGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRN---HILGNADYVFT--------------------SIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQS-SAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVA-IRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELD---KNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK----------------------------GYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPS---------MSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTR---DWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAG-DDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFR--RAGGLFGNHVTYYQ-SDSRGNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALG-RFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKR-----------------------------------CHSRESQGATVNQEIFPDETR-SVRMSEEAEYCSEPSLLSTDMFSYQEDEHRQLT-----CPEEDKREIQPSPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPTTFPRPCPTPPVTPGSR---GRPLRPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGSSSMARRARPVSLTVPSQAG-APGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVAPEDESCAYALGRG-RSEEALADSR---------------SYVSNL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22002-1", "uniprot_id": "CAC1C_RAT", "id": "P22002-1", "name": "Voltage-dependent L-type calcium channel subunit alpha-1C", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIRAFAQPSTPPYQPLSSCLSEDTERKFKGKVVHEAQLNCFYISPGGSNYGSP----RPAHAN-MNANAAAG-------LAPEHIPTPGAALS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WLAAIDAARQAKLMGSAGNATISTVSSTQRKRQ-------------------------------------------------------------------------------------------------------------------------------------QYG----------------------------------------------------------------------------------------------KPKKQGGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIII--LLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRN------------------------GWNLLDFIIVVVGLFSAILEQATKADGANALGGKG-------------------------------------------AGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN-QEGIIDVPAEEDPSPCALETGHGRQCQNG--TVCKPGWDG-------------------PKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPEN----EDEGMDEDKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYN--QPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSP----LGISCWRCVRLLRIFKITRYWNSLSNLVASLLNSLRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQ-TRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPG---MLVCIYFIILFISPNYILLNLFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEK-PAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDT-AGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRN---HILFYFDIVFT--------------------TIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQS-SAINVVKILRVLRVLRPLR-INRAKGLKHVVQCVFVA-IRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAESKGNYITYKTGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELD---KNQRQCVEYALKARPLPRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK----------------------------HYFCDAWNTFDALIVVGSIVDIAITEVHPAEHTQCSPS---------MSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTR---DWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAG-DDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFR--RAGGLFGNHVSYYQ-SDSRSNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALG-RFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKR-----------------------------------CHSRESQGATVSQDMFPDETRSSVRLSEEVEYCSEPSLLSTDILSYQDDENRQLT-----CLEEDKREIQPCPKRSFLRSASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPSTFPRPRPTPPVTPGSR---GRPLQPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGGSSMARRARPVSLTVPSQAG-APGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVVPEDESCVYALGRG-RSEEALPDSR---------------SYVSNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13936-1", "uniprot_id": "CAC1C_HUMAN", "id": "Q13936-1", "name": "Voltage-dependent L-type calcium channel subunit alpha-1C", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVNENTRMYIPEENHQ-----------GSNYGSP----RPAHAN-MNANAAAG-------LAPEHIPTPGAALS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WQAAIDAARQAKLMGSAGNATISTVSSTQRKRQ-------------------------------------------------------------------------------------------------------------------------------------QYG----------------------------------------------------------------------------------------------KPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIII--LLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRN------------------------GWNLLDFIIVVVGLFSAILEQATKADGANALGGKG-------------------------------------------AGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN-QEGIADVPAEDDPSPCALETGHGRQCQNG--TVCKPGWDG-------------------PKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPEN----EDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYN--QPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSP----LGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQ-TRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPG---MLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQELVEK-PAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNPET-TGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRN---HILFYFDIVFTTIFTIEIALKILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQS-SAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVA-IRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELD---KNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPS---------MNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTR---DWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAG-DDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFR--RAGGLFGNHVSYYQ-SDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALG-RLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRERHVPMCEDLELRRDSGSAGTQAHCLLLRKANPSRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLT-----LPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSR---GWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGG-GGSSAARRVRPVSLMVPSQAG-APGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGR--PSEEELQDSR---------------VYVSSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TNI5-1", "uniprot_id": "A0AB32TNI5_DANRE", "id": "A0AB32TNI5-1", "name": "Voltage-dependent L-type calcium channel subunit alpha", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRGLFSWRRLKHERLEEEVEVRFKGKLVSERELGYTHVRPGGSNYSSP----SLAPVPSLNEDEHVGGGGGVLGLAPEHIPTPGAPLS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WQAAIDAARQAKLMGTTG-APISTASSTQRKRQ-------------------------------------------------------------------------------------------------------------------------------------HYT----------------------------------------------------------------------------------------------KPKKQASTASTRPPRALLCLTLKNPIRRACINIVEWKPFEIII--LMTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLCHPNAYLRN------------------------GWNLLDFIIVVVGLFSAILEQATKGDGGTSMGGKA-------------------------------------------AGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHRTCFFYKDGHKGHIAEEKPAPCAPSSAHGRHCSPPNITQCMMGWEG-------------------PNDGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPEN----DDEGLDDDKPRNLSMPASENESVNTDNAPAGDMEGETCCTRMANRISKSKFSRYSRRWNRLCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHHQ--QPEWLTNVQDIANKVLLALFTGEMLLKMYSLGLQAYFVSLFNRFDSFVVCGGILETILVETKIMSP----LGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDET---RRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPG---MLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKRQNSEKP-PLEDEKKEEKIELKSITSDGETPTATKINIDEYTGEDNEEKNPYPVNDFPAGEDDEEEPEMPVGPRPRPLSDIQLKEKAVPMPQAKAFFIFSPSNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAEDPVKNDSFRN---QILGYADYVFT--------------------GIFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLISSGIQS-SAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVA-IRTIGNIVIVTSLLQFMFACIGVQLFKGKFFYCTDTSKQTQAECRGAYILYKDGNVGKPEKAQRSWENSDFNFDDVLQGMMALFAVSTFEGWPGLLYRAIDSHAEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELD---KNQRQCVEYALKARPLRRYIPKNPYQYKVWYVVNSTYFEYLMFTLILLNTICLAMQHHGQSQSFNKAMNILNMLFTGLFTVEMILKLIAFKPRGYFSDPWNVFDFLIVIGSIIDVILSEINHYFVDAWNTFDALIVVGSVVDIAITEVNPADPSSSPPSSVVR-PMGLQNTEDNARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALRDNSQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPCEKGSEINHSSE---DCGSHFAIFYFVSFYMLCAFLIINLFVAVIMDNFDYLTR---DWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIVKKIWKRTSMKLLDQVVPPAG-DDEVTVGKFYATFLIQEYFRKFKKRKEQGLVAKIPPKTALSLQAGLRTLHDMGPEIRRAISGDLTVEEELERAMKETVCAASEDDIFRVKRSGGLFGNHVNYYHQSDGHVSFPQSFTTQRPLHISKSGS-PGEAESPSHQKLVDSTFTPSSYSSSGSNANINNANNTAIGHRYPKP-----TVSTVDGQTGPPLTTIPLPRPTWCFPNKRS--------------------------CFYDTFMRSDSSDSRLPIIRREEASTDETYDETFLDE----RDQAMLSMDMLEFQDEESKQLAPMVEAEVGEERRPWQSPRRRAFLCPTALGRRSSFHLECLRKHNRP--DVSQKTALPLHLVHHQALAVAGLSPLLRRSHSPTLFTRLCSTPPASPSGRSGGGPCYQPVPSLRLEGSGSYEKLNSSMPSVNCSSWYSD----SNGNHSGRAQRPVSLTVPPVTRRDSISLAHGSAGSLVEAVLISEGLGRYAHDPSFIQVAKQEIAEACDMTMEEMENAADNILNANAPPNANGNLLPFIQCRDTGSQESRCSLSLGLSPATGSDGALEAELEESEGAGQRNSPLMEDEDMECVTSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24270-1", "uniprot_id": "CAC1D_DROME", "id": "Q24270-1", "name": "Voltage-dependent calcium channel type D subunit alpha-1", "aln": "MNTGDRKEQASLTPQQQQSPQQPEQQQPITRHDALDSSSANNKLNHKHNNDKDKDTTSDKNWEAGRDLLPASVVIV--DESCASKSQKQPIEPSIVSRSGATSSSQRRRQLQFQRQKEAKLYDRGDGDRDREREREASTSTSTSTSASTTTTNTVMGGGELVNCIAYDDNTLVIERKPSPSSPSTSRRYLKAETPTRGSRKYNRKSSAKSDLEVVVVKPEHHHQHRSPTITLPVPANPLTTSASAGSSPTGAGLAAGLGTASGTVLQQSCSALDPPEDSNQPSGTRRRPTSTELALSNVTSQIVNNATYKLDFKQRRHKSNNGGSESGSLTGIATGPATSPAGPTGPTSSSGKRRKSSCTSCGGGGISAPPPRLTPEEAWQLQPQNSVTSAGSTNSSFSSGGGRDDNSSYSAVGGDSSSSNSCNCDITGDNSTLHGFGVGDVCSFIADCDDNSEDDDGDPNNQDLSSQTLRTAAIVAAVAAAAKEQAQEQSLADCESFSDRRQDADEDVRIIQDCCGGNNDSLEDVGEVDDNADVVVRKNSRNRPSIRRTCRITEEDDDEDENADYGDFDREDQELDDEEPEGTTIDIDEQEQQHDQGDSAEEEDDDEDVDEYFEEEEDDTQAFSPFYSSSAELIDNFGGGAGKFFNIMDFERGASGEGGFSPNGNGGPGSGDVSRTARYDSGEGDLGGGNNIMGIDSMGIANIPETMNGTTIGPSGAGGQKGGAAAGAAGQKRQQRRGKPQPDRPQRALFCLSVKNPLRALCIRIVEWKPFEFLI--LLTIFANCIALAVYTPYPGSDSNVTNQTLEKVEYVFLVIFTAECVMKILAYGFVLHNGAYLRN------------------------GWNLLDFTIVVIGAISTALSQLMKD------------------------------------------------------AFDVKALRAFRVLRPLRLVSGVPSLQVVLNSILKAMVPLFHIALLVLFVIIIYAIIGLELFSGKLHKACRD----EITGEYEENIRPCG----VGYQCPPG--YKCYGGWDG-------------------PNDGITNFDNFGLAMLTVFQCVTLEGWTDVLYSIQDAMGSDWQWMYFISMVILGAFFVMNLILGVLSGEFSKERNKAKNRGDFQKLREKQQIEEDLRGYLDWITQAEDIEPDA----VGGLISDGKGK------QPNEMDSTENLGEEMPEVQMTESRWR------KMKKDFDRVNRRMRRACRKAVKSQAFYWLIIVLVFLNTGVLATEHYG--QLDWLDNFQEYTNVFFIGLFTCEMLLKMYSLGFQGYFVSLFNRFDCFVVIGSITETLLTNTGMMPP----LGVSVLRCVRLLRVFKVTKYWRSLSNLVASLLNSIQSIASLLLLLFLFIVIFALLGMQVFGGKFNFDGKEEKYRMNFDCFWQALLTVFQIMTGEDWNAVMYVGINAYGGVSSYG---ALACIYFIILFICGNYILLNVFLAIAVDNLADADSLSEVEKEEEPHDES-AQKKSHSPTPTIDGMDD-HLSIDIDMEQQELD---------DEDKMDHETLSDEEVREMCE---------EEEEVDEEGMITARPRRMSEVNTATKILPIPPGTSFFLFSQTNRFRVFCHWLCNHSNFGNIILCCIMFSSAMLAAENPLRANDDLN---KVLNKFDYFFT--------------------AVFTIELILKLISYGFVLHDGAFCRSAFNLLDLLVVCVSLISLVSSS-NAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVIVA-VKTIGNIVLVTCLLQFMFAVIGVQLFKGKFFKCTDGSKMTQDECYGTYLVYDDGDVHKPRLREREWSNNRFHFDDVAKGMLTLFTVSTFEGWPGLLYVSIDSNKENGGPIHNFRPIVAAYYIIYIIIIAFFMVNIFVGFVIVTFQNEGEQEYKNCDLD---KNQRNCIEFALKAKPVRRYIPKHGIQYKVWWFVTSSSFEYTIFILIMINTVTLAMKFYNQPLWYTELLDALNMIFTAVFALEFVFKLAAFRFK----------------------------NYFGDAWNVFDFIIVLGSFIDIVYSEIKSKDTSQIAECDIVEGCKSTKKSAGSNLISINFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIVLLFFIYAVVGMQVFGKIALDGGNAITANNNFQTFQQAVLVLFRSATGEAWQEIMMSCSAQPDVKCDMNSDTPGE---PCGSSIAYPYFISFYVLCSFLIINLFVAVIMDNFDYLTR---DWSILGPHHLDEFIRLWSEYDPDAKGRIKHLDVVTLLRKISPPLGFGKLCPHRMACKRLVSMNMPLNSDGTVLFNATLFAVVRTSLSIKTDGNIDDANSELRATIKQIWKRTNPKLLDQVVPPPGNDDEVTVGKFYATYLIQDYFRRFKKRKEQEGKEGHPDSNTVTLQAGLRTLHEVSPALKRAISGNLDELDQEPEPMHRRHHTLFGSVWSSIRRHGNGTFRRSAKATASQSNGALAIGGSASAALGVGGSSLVLGSSDPAGGDYLYDTLNRSVADGVNNITRNIMQARLAAAG----------KLQDELQGAGSGGELRTFGESISMRPLAKN---------------------------------------GGGAATVAGTLPPEANAINYDNRNR------GILLHPYNNVYAPNG----------ALPGHERMIQSTPASPYDQRRLP-------------------TSSDMNGLAESLIG-GVLAAEGLGKYCDSEFVGTAAREMREALDMTPEEMN-------LAAHQILSNEHSLSLIGSSNGSIFGG-------------SAGGLGGAGSGGVGGLGGSSSIRNAFGGSGS--GPSSLSPQHQPYSGTLNSPPIPDNRLRRVATVTTTNNNNKSQVSQNNSNSLNVRANANSQMNMSPTGQP----VQQQSPLRGQGNQ--------------------------TYSS--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50077-1", "uniprot_id": "CCH1_YEAST", "id": "P50077-1", "name": "Calcium-channel protein CCH1", "aln": "--------------------MQGRKRTLTEPFEPNTNPFGDNAAVMTENVEDNSETDGNRLESKPQALVPPALNIVPPESSIHSTEEKKGDEYNGNDKDSSLISNIFRTRVGRSSHENLSRPKLSLKTASFGAAESSRRNVSPSTKSAKSSSQYIDLNDERLRRRSFSSYSRSSSRRVSNSPSSTDRPPRSAKVLSLIAADDMDDFEDLQKGFKSAIDEEGLTWLPQLKSEKSRPVSDVGEDRGEGEQESIPDVHTPNVGASATPGS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IHLTPEPAQNGSVSEGLEGSINNSRKKPSPKFFHHLSPQKEDKDQ-----------------------------------------------------------------------------------------------------------------------------TEVIEYAEDILDFET--------------------------------------------------------------------------------------LQRKLESRPFVLYGHSLGVFSPTNPLRIKIARFLLHRRYSLLYNTLLTFYAILLAIRTYNPHNVVFLYRFSNWTDYFIFILSACFTGNDIAKIIAFGFWDDSEMFKAYGREYKSILQRSGIMKLYIYLREKYGRKLIDFIIPFRIISPGEETKYQRSSLSTSLTKPYGAKENQRPFGTPRAFARSSWNRIDLVSSVSFWLGMFLSIKSYDTKTGIRIFKPLAILRILRLVNVDTGMPSILRGLKYGIPQLVNVSSMLVYFWIFFGILGVQIFQGSFRRQCVWFNPEDPTDTYQYDMQFCGGYLDPVTKRKQN--YIYEDGSEGSVSKGFLCPQYSKCVSNANPYNGRISFDNIVNSMELVFVIMSANTFTDLMYYTMDSD-EMAACLFFIVCIFVLTIWLLNLLIAVLVSSFEIANEEYKKKKFIYGSRKTGYVARIVTGYWKYFKLKANQTKFPNWSQKGLAIYSHVEFIFVILIICDIGMRASVKVSTSANCNNILLKTDRGISIVLFIESLARLVLYLPNMWKFLTKPSYVYDFIISIITLVISCLAVEGVLGHMYAWLSIFHISRFYRVIISFNLTKKLWKQILSNGVMIWNLSSFYFFFTFLVAIIMAVYFEGVIPPEEMADQPFGMYSLPNSFLSLFIIGSTENWTDILYALQKHSPNISSTFFCSVFFIIWFLLSNSVILNIFIALISES-MEVKEEEKRPQQIKHYLKFVYPQKIQEYTHASLVARIRKKFFGGHRNEDTRDFKQFLMRG-----TAIMNIAQNMGELADEFKEPPSENLFKKGLSKLTIGVPSLKRLRMFANNPFYKNSDVVFTETNDING-----RTYILELNEYEDEKLDYLKKYPLFNY-------SYYFFSPQHRFRRFCQRLVPPSTGKRTDGSRFFEDSTDLYNKRSYFHHIERDVFVFIFALATILLIVCSCYVTPLYRMHHKMGTWNWSSALDCAFIG--------------------AFSIEFIVKTVADGFIYSPNAYLRNPWNFIDFCVLISMWINLIAYLKNNGNLSRIFKGLTALRALRCLTISNTARQTFNLVMFDGLNKIFEAGLISLSLLFPFTVWGLSIFKGRLGTCNDGS-LGRADCYN---EYSNSVFQWDIMSPRVYQQPYLHLDSFASAFSSLYQIISLEGWVDLLENMMNSSGIGTPATVMGSAGNALFLVLFNFLSMVFILNLFVSFIVNNQARTTGSAYFTIEEKAWLESQKLLSQAKPKAIPNLIELSRVRQFFYQLAVEKKNFYYASFLQVVLYLHIIMLLSRSYNPGNLIGYQGVYFMFSTSVFLIQEALHMCGEGPR----------------------------LYFRQKWNSIRLSIIIIAFIMNAVAFHVP----------------------ASHYWFHNIKGFFLLVIFLFIIPQNDTLTELLETAMASLPPILSLTYTWGVLFLVYAIALNQIFGLTRLG--SNTTDNINFRTVIKSMIVLFRCSFGEGWNYIMADLTVSEPYCSSDDNSTYTDCG---SETYAYLLLMSWNIISMYIFVNMFVSLIIGNFSYVYRSGGSRSGINRSEIKKYIEAWSKFDTDGTGELELSYLPRIMHSFDGPLSF-KIWEGRLTIKSLVENYMEVNPDDPYDVKIDLIGLNKELNTIDKAKIIQRKLQYRRFVQSIHYTNAYNG----------------CIRFSDLLLQIPLYTAYSAR------------ECLGIDQYVHHLYILG---------------------------------------------KVDKYLENQRNFDVLEMVVTRWKFHCR-------------MKRTIEPEWDVKDPTVSSHISNINVNLEPAPG---------------ILEREPIATPRMDYGVNNFMWSPRMN--------------------------------------QDSTMEPPEEPIDNNDDSANDLIDR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . * : . :..: . .:: . . . . ::: .: :: ::* :: .**:* :: : :.:: *:*::* :*: * *. .. : . ::: ** : . *::*:*: . : * :*:** * . . : : .:: ::.: :** ****. ..: :*..: .: *.::: ::::. *::.*:*:::* *.::: * : . *. : * :* * .* .***: :* ** :: : :**::* *: ::*: ::. :::::**::.** ..*. .:: * : : *:. : . : ** .::. : . : . :. : : : : . * . : .*.. .* ::* :: * :* * ** .: .: *. * *. : .* . : * . .* :: : : . .. . : : : .. :::: :* : .*:* :: .:**: * * . ::. : : : * : :::: :. : : .: * . * * ::: . :: ** : *:.:.. .*: .. .. : . * . :: : .. * * :.: . . .. ** * : . : * :: :: . *: : * * *::*: :* : * . .:: *. :*::*: *: *. . .: :*:: * .**.** :. :: ::..: *:. :..* : ::: * * *: *:.:***:: *.* * . :. . *. . . * :.: :.:*.. .: :*: : ::*** ** ::* . . : : ::: :: .*::*:**.*:: . . . * . : . :.*: : ** * :.: : . ... : :: ::: : : :. :. . *: *.:* :: ::: . : ** : ** : *:: :.: : . . .: :* :: :: ::.:.: : ** * : *: .: :: :**::**: *:** * . . * **:*. :::::***.: **.*: ** : . : .. * ::*: ::. ::::*:**::*:.**.*: * . * :. .:.:: . *:::*.:..*.:: : ::: :. **.* *: *:: * **. * :*.*.. .: *:.: : *.. :: . * . :..: :* * : :. * : :: :: *: :. : .: . . : : . :. .. ** .* * : . . . ", "identical_positions": 216, "similar_positions": 551, "identity": "7.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020205-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GAW9-1", "uniprot_id": "A0A8I6GAW9_RAT", "id": "A0A8I6GAW9-1", "name": "Ubiquitin conjugation factor E4", "aln": "----------MEELSADEIRRRRLARLAGGQTSQP----TTPLTSPQRENPPGPPIAAS-------VPGPSQSLGLNVHNTTPATSPIGAAGVAHRSQSSEGVSSLSSSPSNSLETQSQS------------------------LSRSQSMDIDGVSCEKS-MSQVDVDSGIENMEVDENDR---------REKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIATAARSPDRNLMLNTGSSSGTSPMFCSLGSFSASSLSSLYETSPAPSTSLWSFVPGLSPSFASPSHTAPAASPHSSAPQGAVASQSLSPQSAATHPLSPHSVAPQAAVPSPSLSSHSTASVIATGSQPSSPRYRPYTVTHLWGSSPCPTPRSSILANPPGFPAHSSSPRAVPASSSRQRPRSRAPAFPPASPSAASRRPSSLRISPSMYDSPFSSLFLALSGDSSEEEEEEDEEDDDEGGGDDDFSCVQFGSSLGASGGASTWDSYSDHFTIETCKETDMLNYLIECFDRVGIEEKKAPKMCSQPAVSQLLSNIRSQCISHTALVLQGSLTQPRSLQQPSFLVPYMLCRNLPYGFIQELVRTTHQDEEVFKQIFIPILQGLARAAKECSLDSDYFKYPLMALGELCETKFGKTHPMCNLVASLPLWLPKSLSPGSGRELQRLSYLGAFFSFSVFAEDDAKVVEKYFSGPAITLENTRVVSQSLQHYLELGRQELFKILHSILLNGE-TREAALSYMAAIVNANMKKAQMQADDRLVSTDGFMLNLLWVLQQLS------TKIKLETVDPTYIFHPRCRITLPNDETRINATMEDVNEWLTELYGDQPPFSEPKFPTECFFLTLHAHHLSILPSCRRYIRRLRAIRELNRTVEDLKNNESQWKDSPLATRHREMLKRCKTQLKKLVRCKACADAGLLDESFLRRCLNFYGLLIQLMLRVLDPAYPD----ITLPLN---------------SEVP-KVFAALPEFYVEDVAEFLFFIVQYSP-QVLYEPCTQDIVMFLVVMLCNQNYIRNPYLVAKLVEVMFMTNPSVQPRTQKFFEMIENH-PLSTKLLVPSLMKFYTDVEHTGATSEFYDKFTIRYHISTIFKSLWQNIAHHG--TFMEEFNSGKQFVRYINMLINDTTFLLDESLESLKRIHEVQEEMKNQEQWDQLPRDQQ-QARQSQLAQDERVSRSYLALATETVDMFHLLTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCRDLKVENPEKYGFEPKKLLDQLTDIYLQLDCAR-FAKAIADDQRSYSKELFEEVISKMR-KAGIKSTIAIEKFKLLAEKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTI-MDRSIILRHLLNSPTDPFNRQMLTESMLEPVPELKEQIQAWMREKQSSDH-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ES00-1", "uniprot_id": "UBE4B_MOUSE", "id": "Q9ES00-1", "name": "Ubiquitin conjugation factor E4 B", "aln": "----------MEELSADEIRRRRLARLAGGQTSQP----TTPLTSPQRENPPGPPIAAS-------APGPSQSLGLNVHNMTPATSPIGAAGVAHRSQSSEGVSSLSSSPSNSLETQSQS------------------------LSRSQSMDIDGVSCEKS-MSQVDVDSGIENMEVDENDR---------REKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIATAARSPDRNLMLNTGSSSGTSPMFCNMGSFSTSSLS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLGASGGASNWDSYSDHFTIETCKETDMLNYLIECFDRVGIEEKKAPKMCSQPAVSQLLSNIRSQCISHTALVLQGSLTQPRSLQQPSFLVPYMLCRNLPYGFIQELVRTTHQDEEVFKQIFIPILQGLALAAKECSLESDYFKYPLMALGELCETKFGKTHPMCNLVASLPLWLPKSLSPGSGRELQRLSYLGAFFSFSVFAEDDAKVVEKYFSGPAITLENTRVVSQSLQHYLELGRQELFKILHSILLNGE-TREAALSYMAALVNANMKKAQMQADDRLVSTDGFMLNLLWVLQQLS------TKIKLETVDPTYIFHPRCRITLPNDETRINATMEDVNERLTELYGDQPPFSEPKFPTECFFLTLHAHHLSILPSCRRYIRRLRAIRELNRTVEDLKNNESQWKDSPLATRHREMLKRCKTQLKKLVRCKACADAGLLDESFLRRCLNFYGLLIQLMLRILDPAYPD----VTLPLN---------------SEVP-KVFAALPEFYVEDVAEFLFFIVQYSP-QVLYEPCTQDIVMFLVVMLCNQNYIRNPYLVAKLVEVMFMTNPSVQPRTQKFFEMIENH-PLSTKLLVPSLMKFYTDVEHTGATSEFYDKFTIRYHISTIFKSLWQNIAHHG--TFMEEFNSGKQFVRYINMLINDTTFLLDESLESLKRIHEVQEEMKNKEQWDQLPRDQQ-QARQSQLAQDERVSRSYLALATETVDMFHLLTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCRDLKVENPEKYGFEPKKLLDQLTDIYLQLDCAR-FAKAIADDQRSYSKELFEEVISKMR-KAGIKSTIAIEKFKLLAEKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTV-MDRSIILRHLLNSPTDPFNRQMLTESMLEPVPELKEQIQAWMREKQSSDH-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95155-1", "uniprot_id": "UBE4B_HUMAN", "id": "O95155-1", "name": "Ubiquitin conjugation factor E4 B", "aln": "----------MEELSADEIRRRRLARLAGGQTSQP----TTPLTSPQRENPPGPPIAAS-------APGPSQSLGLNVHNMTPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQS------------------------LSRSQSMDIDGVSCEKS-MSQVDVDSGIENMEVDENDR---------REKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSR-----------------------------------AASQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSG-----VSILSSSPSPPALASSPQAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISP----------------------------------------------SLGASGGASNWDSYSDHFTIETCKETDMLNYLIECFDRVGIEEKKAPKMCSQPAVSQLLSNIRSQCISHTALVLQGSLTQPRSLQQPSFLVPYMLCRNLPYGFIQELVRTTHQDEEVFKQIFIPILQGLALAAKECSLDSDYFKYPLMALGELCETKFGKTHPVCNLVASLRLWLPKSLSPGCGRELQRLSYLGAFFSFSVFAEDDVKVVEKYFSGPAITLENTRVVSQSLQHYLELGRQELFKILHSILLNGE-TREAALSYMAAVVNANMKKAQMQTDDRLVSTDGFMLNFLWVLQQLS------TKIKLETVDPTYIFHPRCRITLPNDETRVNATMEDVNDWLTELYGDQPPFSEPKFPTECFFLTLHAHHLSILPSCRRYIRRLRAIRELNRTVEDLKNNESQWKDSPLATRHREMLKRCKTQLKKLVRCKACADAGLLDESFLRRCLNFYGLLIQLLLRILDPAYPD----ITLPLN---------------SDVP-KVFAALPEFYVEDVAEFLFFIVQYSP-QALYEPCTQDIVMFLVVMLCNQNYIRNPYLVAKLVEVMFMTNPAVQPRTQKFFEMIENH-PLSTKLLVPSLMKFYTDVEHTGATSEFYDKFTIRYHISTIFKSLWQNIAHHG--TFMEEFNSGKQFVRYINMLINDTTFLLDESLESLKRIHEVQEEMKNKEQWDQLPRDQQ-QARQSQLAQDERVSRSYLALATETVDMFHILTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCRDLKVENPEKYGFEPKKLLDQLTDIYLQLDCAR-FAKAIADDQRSYSKELFEEVISKMR-KAGIKSTIAIEKFKLLAEKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTI-MDRSIILRHLLNSPTDPFNRQTLTESMLEPVPELKEQIQAWMREKQNSDH-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q5A9-1", "uniprot_id": "F1Q5A9_DANRE", "id": "F1Q5A9-1", "name": "Ubiquitin conjugation factor E4 B", "aln": "----------MEQLSPEEIRRRRLARLAGGQTSQPSTPLSTPLTSPQRETPPGPLPGPSGASSQPVPPAPSHTLALNAQNVTPATSPMGASGVAYRSQSSEGVSSLSSSPSNSLETQSQS------------------------LSRSQSMDIDTASCEKS-MSQVDVDSGIENMEVEDSDR---------REKRNLAEKDSSSNPDVSEELALQLICKILRVSWKEQDRDVIFLPSLAAEFQKNPKDVYSDFKDLIGQILMEALMMSTRSRDCNPFASLTATSQPIT-AARSPDHHLTLVPPSSQGGSPMMPCAGSFGASSLS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLGASAGGMAGDSGSDRFTIESCKETEMLNYLIERFDSVGMEERKAPKMCSQPAVSQLLSNIRSQCISHAALVLQGALTQPRAPLQPSLLVPYMLCRNLPYGFIQELVRMTHQEEDVFKQIFVPILQGLALAVKECSFDSDNFKFPLMALAELCEIKFGKTHPVCNLITSLPLWCPDPLSPGTGREIQRLSFLGAFFSLSVFAEDDTKVGDKYFSGPAITMENTRVVSQSLQHYLESARGDLFKILHNILLNGE-TREAALSYMAALVNRNVKKAQMQTDDKLVSTDGFMMNFLWVLQQLS------MKIKLETVDPLYIFHPKCRLNVSPEETRLKATMEELKSWLTELHEDPTKFSEPKFPTECFFLTLHAHHLSILPCCRRYIRRLRAIRDLNRTVEELKNSENQWKDSPLAGRHREMLKRCKTQLKKLVRSKACADAGLLDENLLRRCLQFFSMVIQLILRMVEPAFPH----VSLPLN---------------PEIP-KSFAALPEFYIEDVAEFMLFIVQYFP-QVLYEPCTEDIVTFLIVFICSQNYIKNPYLIAKLVEVLFVTNPAVQPRTQRFFEMLENH-PLSVNQLVPALMKFYTDVEHTGATSEFYDKFTIRYHISTIFKSLWQNINHQG--TFLEEFNSGKQFVRYINMLINDTTFLLDESLESLKRIHEIQEEMKNKEQWDLLPREQQ-QSRQSQLTQDERVSRSYLALATETVDMFHILTKQVQKPFLRPELGPRLAAMLNYNLQQLCGPKCRDLKVENPEKYGFEPKKLLDQLTDIYLQLDCPR-FAKAIADDQRSYSRELFEEVISKMR-KAGIKSTIAIEKFKLLLEKVEEIVARNSQSEMDYSDAPDEFKDPLMDTLMTDPVQLPSGNI-MDRSIILRHLLNSPTDPFNRQPLTESMLEPVPELKERIQAWMREKQTGRY-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VK44-1", "uniprot_id": "Q9VK44_DROME", "id": "Q9VK44-1", "name": "Ubiquitin conjugation factor E4 B", "aln": "MPEEEPPQKPMEEEEDDDQEQDQDQDHEQDQHEQDQQPQLAQGEIPGQQLPEQPNPDVQ-------PQQPAESVVVTELSAEEMRARR-LRTLAARSGIQCALAPLTTTPRKPTNVSGESRLVREATPGEKEVSLPTSAPAWRELSGKPDMDVEMKSVVSTPMQDVDMTTALSLPTAEATKRSVLQSCKISAGNAELSIETVVGPKKSADEQNEQLLSRLLNATWNEYGSGSIICAQSASFLEQQPHRRFDFECIVANVLMEAVLKIYNGELIEGDGVSVKADDKEFSSAKKIKSDDTEVQEILANAVATGGATASGETAAAAAGASG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PIEATSSEAAGTCVAPPVLSIVATTKHHVLLYLIRCYQNYQTECSRKTPLTQPALQLAFEQVMRMTVLVLTDRIYQN----LNGHMDQSALLDLMYMAKVSEPFLIDLIAHTHQDREAFDTIFSQVLRGLFAGMQRNICTSKISVQQIEWLSKLVVIKVGSVRPIADLVSRQPNFLPPICTKISGREIVKCSFLGPFLSVSLFAEENIKFAEFTTKN-----KLEDASSSRLRWELHSMRTNMHVVFHSLCVNAS-SRPKTLEYIASILRHNDRRVQFASDEKLLARDGFMINLMSVLQQLS------VKIKLDRIEPNFHYYKNSLVNIEQD-TKIRYSEEEYRNFLARDFS--QPVENTNFQTQCWFLTLQAHHLGYLPAIQRYRQKVRAIKELQKLIDELDRTKSHWMNSRYANRNNQFKERWEKQLRKLNRSKTCCEITLLDPGLLQRCTEFYSTVCEFMLYQFEGRPIEGPFISKLPVQ---------------QLLPTDAFSALPEWYIDDIAEFILFTMQHAN-MDIRQGIDHSIITWLLTCVCASHLIKNPYVTAKLVEVMFVFS---LKPANSVNAAMWNH-ELAQNALVSSLMRFYVDVETTGQSTEFYDKFTIRYHISHLFKSMWENPIHRQ--AVICESRVGNQFVKFVNMLMNDTTFLLDECLENLKRIHQTQQLLSDKANLSKMSAEQQ-QSRLTQLATDERQCRSYLTLARETVDLFHYLTSDIKEPFMRDELVDRLSSMLNFNLKQLAGPKCNDLKVKNPAKYGWEPRSLLAQIFDIYLHLDCDR-FAEALAADERSFDVQICNEAASRIK-RLALRSAVEVERFKALTQRAHEIYVTNLQTEDECADAPDEFKDPLMDTLMSDPVVLPSGTV-MDRAIITRHLLNSCTDPFNRQPLTEDMLVANIELKQRIDAWRKEQRGKRNNC---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54860-1", "uniprot_id": "UFD2_YEAST", "id": "P54860-1", "name": "E4 ubiquitin-protein ligase UFD2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTAIEDILQITTDPSDTRGYSLLKSEEVPQGSTLGVDFIDTLLLYQLTENE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLDKPFEYLNDCFRRNQQQKRITKNKPNAESLHSTFQEIDRLVIGYGVVALQIENFCMNGAFIN-YITGIVSNVNSYTDFLSQIIQRAILEGTALD-LLNAVFPTLLEYCNKHVSHFDLNESVIYNNVLTIFELFVTFKPIAEIFTKIDGFFADYSCK--PQDFERKTILGPILSLS--PIEAAVAIRNYGDNLLRSKQQTAMIHESLQAEHKVVIDRLFFIVDKLVRGSLNSRTDMISYFAHIANKNHLRRADHPPFKELSSNGFMSNITLLLVRFSQPFLDISYKKIDKIDANYFNNPSLFIDLSGE-TRLNSDFKEADAFYDKNRK--TADSKPNFISDCFFLTLTYLHYGLGGTLSFEEKMGSEIKALKEEIEKVKKIAANH--DVFARFITAQLSKMEKALKTTESLRFALQGFFAHRSLQLEVFDFICGASTFLIRVVDPEHEFPFKQIKLPLIPDQIGVENVDNADFLRAHAPVPFKYYPEFVVEGPVNYSLYISKYQTSPIFRNPRLGSFVEFTTMVLRCPELVSNPHLKGKLVQLLSVGAMPLTDNSPGFMMDIFEHDELVNKNLLYALLDFYVIVEKTGSSSQFYDKFNSRYSISIILEELYYKIPSYKNQLIWQSQNNADFFVRFVARMLNDLTFLLDEGLSNLAEVHNIQNELDNRARGAPPTREEEDKELQTRLASASRQAKSSCGLADKSMKLFEIYSKDIPAAFVTPEIVYRLASMLNYNLESLVGPKCGELKVKDPQSYSFNPKDLLKALTTVYINLSEQSEFISAVAKDERSFNRNLFVRAVDILGRKTGLASPEFIEKLLNFANKAEEQRKADEEEDLEYGDVPDEFLDPLMYTIMKDPVILPASKMNIDRSTIKAHLLSDSTDPFNRMPLKLEDVTPNEELRQKILCFKKQKKEEAKHKASE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : . :.: . : . : . . : ** : : . . : : * .. : : : *: ::: : : .:. :: :: * :. . : . . :*:.::.: : . ::: : : **.::*.* . : .. : . *: . :. :...: .. :* :.*:* : . * : . : :: :*** *: :* ::* *:: ::. : : : : *::. :: . .:.:* ::*:**** * . : *: *:. ::.:.. : . * .: :. *:. : . : : . .: . :* ::: .: .**: . * **: ::. .:: :: :: : : .:: : : . : **:: .***::: : : . : :* * : *: :*: **. ** ** :::*****. ** ** :::.:: : . . . .. **::: ::** ****** *..* .:*: *: :.:: . . ::: : ::*: .* .:* ** :::.:*. :.:: .*: *: **::***:**:.* **** :***::* .*.::*:.** : :*::*. * .*:* *:**:. :: .. . : : .: *. :*:: : ::..* : . : : .*.**** **** *:*.*** **:..: :**: * ***.. ****** *. . : . **:::* .: :::: ", "identical_positions": 150, "similar_positions": 315, "identity": "10.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020208-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43763-1", "uniprot_id": "TLX2_HUMAN", "id": "O43763-1", "name": "T-cell leukemia homeobox protein 2", "aln": "MEPGMLGPHNLPH--HEPISFGIDQILSGPETPGGGLGLGRGGQGHGENGAFSGGYHGASGYGPAGSLAP-LPGSSGVGP-----------------GGVIRVPAHRPLPVPP-------PAGGAPAVPGPSGLGGAGGLAGLTFPWMDSGRRFAKDRLTAALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALPRPLRPPLPPDPLCLHNSSLFALQNLQPWAEDNKVASVSGLASVV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61663-1", "uniprot_id": "TLX2_MOUSE", "id": "Q61663-1", "name": "T-cell leukemia homeobox protein 2", "aln": "MEPAVLAAHHLPH--HEPISFGIDQILSGPEPPGGGLGPGQSGQSHGESAAFSSGFHGASGYAPAGSLAS-LPRGSGVGP-----------------GGVIRVPAHRPLPVPP-------PSGAAPAVPGPSGLGGAGGLAGLTFPWMDSGRRFAKDRLTAALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALPRPLRPPLPPDPLCLHNSSLFALQNLQPWAEDNKVASVSGLASVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2R8QHC0-1", "uniprot_id": "A0A2R8QHC0_DANRE", "id": "A0A2R8QHC0-1", "name": "", "aln": "MEHTGIEEVNQTHQQHETISFGIDQILNGSDQSSSCMLPSRTGD--PDYALTPNVYNGYNSMYPACSMAAGLAGSYNVNMNMNVSMNMNVNVNSGNAGGVIRVPAHRPMPPAPHQPTAGHPPSIAAGIPTMPTVPSMGSPHSFTFPWMESSRRFAKDRLTAALSPFSVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERATLAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRLMLQLQQEAFQKTLSQPLQQDPLCLHNSSLYALQNLQPWAEDNKVTSVTSVASVV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : : .* **.*********.*.: ... : .: *: : . .. ::* .. ** *:*. *. . .*. ***********:* .* *.. *..:* . : . *. .:*****:*.**************** ************************* *: ***:** ***********:*****:*****************************::*.**:*:***:*: :.* ** **********:**************:**:.:****", "identical_positions": 179, "similar_positions": 61, "identity": "57.56%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020213-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXP6-1", "uniprot_id": "MKRN1_MOUSE", "id": "Q9QXP6-1", "name": "E3 ubiquitin-protein ligase makorin-1", "aln": "--MAEAAAPGTTATTSGAGA-----------------------AAAAVA----AASLTSIPTVAAPSPGAGGGGGGSDGSGGG-------------------------------WTKQVTCRYFMHGVCKEGDNCRYSHDLSDSPYGVVCKYFQRGYCVYGDRCRYEHSKPLKQEEVTATDLSAKPSLAASSSLSSGVGSLAEMNSGEAESRN--------------PSFPTVGAGSEDWVNAIEFVPGQPYCGRTAPS-CTEVPPQGSVTKEESEKEPTT--------------VETKKQLCPYAAVGECRYGENCVY-LHGDSCDMCGLQVLHPVDAAQRSQHIKSCIEAHEKDMELSFAVQRTKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLIQKYKEAMSNKACRYFDEGRGSCPFGGNCFYKHAYPDGRREEPQ--RQKVGTSSRYRAQRRSHFWELIEEREN-NPFDNDEEEVVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDFYDLDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2QC40-1", "uniprot_id": "A0A0G2QC40_RAT", "id": "A0A0G2QC40-1", "name": "RING-type E3 ubiquitin transferase", "aln": "--MAEAAAPGTTATTSGAGA-----------------------AAAAVA----AASLTSIPTVAAPSPGAGGGGGGSDGSGGG-------------------------------WTKQVTCRYFMHGVCKEGDNCRYSHDLSDSPYGVVCKYFQRGYCVYGDRCRYEHSKPLKQEEVTATDLSAKPSPAASSSLPSGVGSLAEMNPGEAESRN--------------PNFPTVGAGSEDWVNAIEFVPGQPYCGRTAPS-CTEVPLQGSVTKEESEKEPTT--------------VETEKQLCPYAAVGECRYGENCVY-LHGDSCDMCGLQVLHPMDAAQRSQHIKSCIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLIQKYKEAMSNKACRYFDEGRGSCPFGGNCFYKHAYPDGRREEPQ--RQKVGTSSRYRAQRRSHFWELIEEREN-NPFDNDEEEVVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDFYDLEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UHC7-1", "uniprot_id": "MKRN1_HUMAN", "id": "Q9UHC7-1", "name": "E3 ubiquitin-protein ligase makorin-1", "aln": "--MAEAATPGTTATTSGAGA-----------------------AAATAA----AASPTPIPTVTAPSLGAGGGGGGSDGSGGG-------------------------------WTKQVTCRYFMHGVCKEGDNCRYSHDLSDSPYSVVCKYFQRGYCIYGDRCRYEHSKPLKQEEATATELTTKSSLAASSSLSSIVGPLVEMNTGEAESRN--------------SNFATVGAGSEDWVNAIEFVPGQPYCGRTAPS-CTEAPLQGSVTKEESEKEQTA--------------VETKKQLCPYAAVGECRYGENCVY-LHGDSCDMCGLQVLHPMDAAQRSQHIKSCIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLILKYKEAMSNKACRYFDEGRGSCPFGGNCFYKHAYPDGRREEPQ--RQKVGTSSRYRAQRRNHFWELIEERENSNPFDNDEEEVVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDFYDLDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q13434-1", "uniprot_id": "MKRN4_HUMAN", "id": "Q13434-1", "name": "Putative E3 ubiquitin-protein ligase makorin-4", "aln": "--MAEAAAPGTTVTTSGAGA-----------------------AAAEAAETAEAVSPTPIPTVTAPSPRAGGGVGGSDGSDGSGGRGDSGAYDGSGACGGSDACDGSGDSSGDSWTKQVTCRYFKYGICKEGDNCRYSHDLSDRLCGVVCKYFQRGCCVYGDRCRCEHSKPLKQEEATATELTTKSSLAASSSLSSIVGPLVEMNTNEAESRN--------------SNFATVVAGSEDWANAIEFVPGQPYCGRTVPS-CTEAPLQGSVTKEESEEEQTA--------------VETKKQLCPYAAVGQCRYGENCVY-LHGDLCDMCGLQVLHPMDAAQRSQHIQACIEAHEKDMEFSFAVQRSKDKVCGICMEVVYEKANPNEHRFGILSNCNHTFCLKCIRKWRSAKEFESRIVKSCPQCRITSNFVIPSEYWVEEKEEKQKLIQKYKEAMSNKACKYFDEGRGSCPFGENCFYKHMYPDGRREEPQ--RQQVGTSSRNPGQQRNHFWEFFEEGANSNPFD-DEEEAVTFELGEMLLML-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4VBT5-1", "uniprot_id": "MKRN1_DANRE", "id": "Q4VBT5-1", "name": "Probable E3 ubiquitin-protein ligase makorin-1", "aln": "--MAEAAAASTAAPAVIGG-----------------------------------------------------------------------------------------------WTKHVTCRYFMHGLCKEGENCRYSHDLSSCKQTMICKFFQKGCCAFGDRCRYEHTKPSKQDEVPS----SKPSMPLTAAP--LAGTPEPVSDGPGGTTG--------------AQEKPQGSGAVDWVNAAEFVPGQPYCGRADPV-LCEGP--GPLIEEEYEKEQAN--------------KEMKKQLCPYAAVGECRYGLNCAY-LHGDVCDMCGLQVLHPSDTSQRSQHIRACIEAHEKDMEISFAIQRSKDMMCGVCMEVVFEKTNPSERRFGILSNCCHCYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEDKEEKQQLIQKYKDGMGTKPCRYFDEGRGTCPFGANCFYKHAFPDGRLEEPQPQRRQNGSNGRNRNTRRTHLWDLLDERENSDSFDNEDEEMVRFELSEMLLMLLAAGTDDDVTDSEDEWDLFHEELDDYYELYL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZY41-1", "uniprot_id": "D3ZY41_RAT", "id": "D3ZY41-1", "name": "RING-type E3 ubiquitin transferase", "aln": "--MEESTAPMEAYEAAGAEAGAEGG-EGVSAPPPPQFEASGASAVASSAPLQEASGLAPFLMAPVPANRRAASLRPAPAEGGGARSG--------------------PERNTGSWTKQILCRYYLHGQCKEGDNCRYSHDLSGRRKARGGQDSQPRASADRGPKMATHWEPPTQEVAEAPPTASSSSLPLIGSAAERGFSEAEIDNAGIGSAAERGFPEAEIDNAGLAAGAAGGAGAEGWEGAIEFVPGQPYRGRMIPPHGPEAPLQSPEIEREHMAMGMG----------------MPLPLCRYAARGQCLRGDRCAY-PHGEICDMCGQQALHPWDAAQQEAHRRACVEAHERDMELSFAVQRSMDKVCGICMEVVYEKADPSDRRFGILFSCNHTYCLKCIRRWRSATQFENRISKSCPQCRVSSGFVIPSEFWVEEEEEKEKLVQQYKEGMSQKACRYFAGGLGHCPFGEFCFYKHEYPEGWRDQPP--RPDGGGSS---SAYWHQVLEPVQLREGSVLFKSRKKEHSVLRLANQLLKKLLCLRG-SFSISDDRWLLLQYQLEEYFNLNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60764-1", "uniprot_id": "MKRN3_MOUSE", "id": "Q60764-1", "name": "E3 ubiquitin-protein ligase makorin-3", "aln": "--MEESTAPIEAHAAAGAEAGAEGG-EGVSVPPPPQFEAAGASAGVSSAPLQQASGLAPLLVTPGPAIRRAASLRPAPAEGGGARSG--------------------PERNSGSWTKQILCRYYLHGQCKEGDNCRYSHDLSGRRRSRGGQDAQPRASADRGPKMATRWEPPTQEVAEAPPAASSSSLPLIGSAAERGFTEAEIDNAGIRSAAERGFSEAEIDNASLAAGAAAGAGAEGWEGAIEFVPGQPYRGRMVPPHGPEAPLQSPAIEREHMAMGMGMPMPVPMPMPVPMPVPMPLPLCRYAARGQCLRGDRCAY-PHGEICDMCGQQALHPWDAAQQEAHRRACVEAHERDMELSFAVQRSMDKVCGICMEVVYEKADPSDRRFGILFSCNHTYCLRCIRRWRSATQFENRISKSCPQCRVSSGFVIPSEFWVEEEEEKEKLVQQYKEGMSQKACRYFAGGLGHCPFGEFCFYKHEYPEGWRDQPP--RPDGGGSS---SAYWHQVLEPVQLREGNVLFKSRKKEHSVLRLANQLLKKLLCLRG-SSSFSDDRWLLLQYQLEEYFSLNL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13064-1", "uniprot_id": "MKRN3_HUMAN", "id": "Q13064-1", "name": "E3 ubiquitin-protein ligase makorin-3", "aln": "--MEEPAAPSEAHEAAGAQAGAEAAREGVSGPDLPVCEPSGESAAPDSALPHAARGWAPFPVAPVPAHLRRGGLRPAPASGGGAWPSPL------------------PSRSSGIWTKQIICRYYIHGQCKEGENCRYSHDLSGRKMATEGGVSPPGASAGGGPSTAAHIEPPTQEVAEAPPAASSLSLPVIGSAAERGFFEAERDNADR--------------------GAAGGAGVESWADAIEFVPGQPYRGRWVAS-APEAPLQSSETERKQMAVGSG------------------LRFCYYASRGVCFRGESCMY-LHGDICDMCGLQTLHPMDAAQREEHMRACIEAHEKDMELSFAVQRGMDKVCGICMEVVYEKANPNDRRFGILSNCNHSFCIRCIRRWRSARQFENRIVKSCPQCRVTSELVIPSEFWVEEEEEKQKLIQQYKEAMSNKACRYFAEGRGNCPFGDTCFYKHEYPEGWGDEPP--GP-GGGSF---SAYWHQLVEPVRMGEGNMLYKSIKKELVVLRLASLLFKRFLSLRD-ELPFSEDQWDLLHYELEEYFNLIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VY21-1", "uniprot_id": "Q9VY21_DROME", "id": "Q9VY21-1", "name": "RING-type E3 ubiquitin transferase", "aln": "-------------MTSSRQN------------------------------------------------------------------------------------------------LHKICRYRLRGNCRFDDLCRYSHDVLQ---------------NDNLRPQISNNADEVVG------HANRYSRPMTGANA--------------------------------------------------------------------------------------------------------------------------------------------------------------TEEMKLSFAIAKSQDKMCGICLETVVKKRG-RECRFGILPKCKHIFCLTCIRRWRQAEYIEDNVKRGCPECRVFSEFVCPSAYWVDTKEEKDKLLSEYRAAMGAKDCKYFNGGLGKCPFGTNCFYNHRSLAGD----------------------NRIQRH-------------------------------SMEDDDF----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VY20-1", "uniprot_id": "Q9VY20_DROME", "id": "Q9VY20-1", "name": "RING-type E3 ubiquitin transferase", "aln": "-------------MSYRRS--------------------------------------------------------------------------------------------------QTICRFHLLGICRFGDLCRFSHDETTP--------------NDNQSPQISEIADEVVENEQVVASTSSYSRQMTWANAPEFVPRYKANSADFQA----------------------------------------------------------TEGVQDICPYGG----------------------------SCIWGSKCSYPLHMEICKMCDLYCLHPMDQNQRRAHNRECLEQHEQAMELSFAIARSKDKMCGICFDTVVEKKG-RERRFGILSKCKHIFCLTCIRTWRQAHQFEATVTRGCPECRVFSEFVCPSAYWVDTKEEKDKLLSEYRAAMGAKDCKYFNGGLGKCPFGNKCFYRHHRRCDD----------------------NQTQSN-------------------------------AVNSD------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VP20-1", "uniprot_id": "Q9VP20_DROME", "id": "Q9VP20-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MSAVTSSDTAISGMALGRS--------------------------------------------------------------------------------------------------QTICRYYVRGICRFGELCRFSHDLSRGRPECEEQ------VATDVLPKPSTSSSSTIGSR----SASISSQQRNWANAPVFVPSQKRYTAHEQSEF---------------------ETTVDPEAVMEAQAGASYDTLAPGVSWAEVVGGPSSLNKEDYGEENS----------------------------SCAWGEFSAYPIHMELCEMCDQYCLHPTDQVQRRSHNRECLQQHEQAMELSFAIARSKDKTCGICFDTIMEKAG-REKRFGILPNCNHIFCLECIRTWRQAKQFENKITRACPECRVCSDFVCPSAFWMETKEEKDKLLNDYRAALGAKDCKYFKKGEGKCPFGNKCFYKHALPNGDIVDVG------------LPKRTRKLQSQNEIIDLLDIYLWDYVDRRDYHWLEMISSDITSSESSDYSDED------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VVS2-1", "uniprot_id": "Q9VVS2_DROME", "id": "Q9VVS2-1", "name": "RING-type E3 ubiquitin transferase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTVASNDQHVDTGVLPVPSTNSPSSQIEQKGNEAIVPNYKAATAGEQGEA-----------------------------------------------------------------------------------------------------------QAGATCTTVAVRPSGVATSADIVKGSSSVSSHVQPSWRSSFAR--SQDKKCGICFETIMEKEG-GDKRFGILPSCNHVFCFQCICTWRHATQYAYQVTRACPECRVWSNFVCPSAFWVEEKVAKDQLINDHLAAMRARDCKYFKQGQGVCLFGNKCFYKHSIPNADYVDVG-------------------LPTHALGLPIPSDFSGLGNCLILVPFPNMFFDDFSNSDDYDFSDVN------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02799-1", "uniprot_id": "LEE1_YEAST", "id": "Q02799-1", "name": "Zinc finger protein LEE1", "aln": "---------------------------------------------------------------------------------------------------------------------MDAFENMSVSNHPGGNARRNSQSANEMLAS----------QIQDFQNIPRSFNDSNANVNLSKNCTVGNQLPFSSRQQKIIMEHLLITKNNSQQQK----------------------------------------------------------------------------------------------------------DYSHVPCKFFKMGNCQAGSSCPFSHSPDIISSANNLPCKYFAKGNCKFGNKCVNAHVLPNGFKMNSKEPIDITPPSQNNYLSHARSASFSTYTSPPLSAQTEFSHSASNANYFSSQYLMYSPQKSPEALYTEFFSPPSSSSSYINYSYNNSNINAYSPVSSSSSNIWQEQGQ-----------------TTLSNPSVNQNLRYRTGPAIQEESDNEIEDLLIHNFNSRYCHE-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . * . . :.* . : : . : : . . .* : : . : : . . *: . . . :. . ", "identical_positions": 4, "similar_positions": 30, "identity": "0.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020213-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VY21-1", "uniprot_id": "Q9VY21_DROME", "id": "Q9VY21-1", "name": "RING-type E3 ubiquitin transferase", "aln": "-------------------------MTSSRQNLHKICRYRLRGNCRFDDLCRYSHDVLQ---------NDNLRP-QISNNADEVVG--------------------HANRYSRPMTGANA-------------------------------------------------------------------------------------------------------------TEEMKLSFAIAKSQDKMCGICLETVVKKRG-RECRFGILPKCKHIFCLTCIRRWRQAEYIEDNVKRGCPECRVFSEFVCPSAYWVDTKEEKDKLLSEYRAAMGAKDCKYFNGGLGKCPFGTNCFYNHRSLAGD----------NRIQRH-------------------------------SMEDDDF------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VY20-1", "uniprot_id": "Q9VY20_DROME", "id": "Q9VY20-1", "name": "RING-type E3 ubiquitin transferase", "aln": "-------------------------MSYRRS--QTICRFHLLGICRFGDLCRFSHDETTP--------NDNQSP-QISEIADEVVENEQVV--------------ASTSSYSRQMTWANAPEFVPRYKANSADFQA-------------------------------------TEGVQDICPYGGSCIWGSKCSYPLHMEICKMCDLYCLHPMDQNQRRAHNRECLEQHEQAMELSFAIARSKDKMCGICFDTVVEKKG-RERRFGILSKCKHIFCLTCIRTWRQAHQFEATVTRGCPECRVFSEFVCPSAYWVDTKEEKDKLLSEYRAAMGAKDCKYFNGGLGKCPFGNKCFYRHHRRCDD----------NQTQSN-------------------------------AVNSD--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VP20-1", "uniprot_id": "Q9VP20_DROME", "id": "Q9VP20-1", "name": "RING-type E3 ubiquitin transferase", "aln": "------------MSAVTSSDTAISGMALGRS--QTICRYYVRGICRFGELCRFSHDLSRGRPECEEQVATDVLP-KPSTSSSSTIGSR------------------SASISSQQRNWANAPVFVPSQKRYTAHEQSEFETTVDPEAVMEAQAGASYDTLAPGVSWAEVVGGPSSLNKEDYGEENSSCAWGEFSAYPIHMELCEMCDQYCLHPTDQVQRRSHNRECLQQHEQAMELSFAIARSKDKTCGICFDTIMEKAG-REKRFGILPNCNHIFCLECIRTWRQAKQFENKITRACPECRVCSDFVCPSAFWMETKEEKDKLLNDYRAALGAKDCKYFKKGEGKCPFGNKCFYKHALPNGDIVDVGLPKRTRKLQSQNEIIDLLDIYLWDYVDRRDYHWLEMISSDITSSESSDYSDED--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VVS2-1", "uniprot_id": "Q9VVS2_DROME", "id": "Q9VVS2-1", "name": "RING-type E3 ubiquitin transferase", "aln": "-------------------------MSTVASNDQHVD----TGVLPVPSTNSPSSQIEQKG-------NEAIVPNYKAATAGEQGEAQAGA--------------TCTTVAVRPSGVATSADIVKGSSSVSS-------------------------------------------------------------------------------------------------HVQPSWRSSFARSQDKKCGICFETIMEKEG-GDKRFGILPSCNHVFCFQCICTWRHATQYAYQVTRACPECRVWSNFVCPSAFWVEEKVAKDQLINDHLAAMRARDCKYFKQGQGVCLFGNKCFYKHSIPNADYVDVGLPTHALGLPIPSDFSGLGNCLILVPFPN-------MFFDDFSNSDDYDFSDVN--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9H000-1", "uniprot_id": "MKRN2_HUMAN", "id": "Q9H000-1", "name": "E3 ubiquitin-protein ligase makorin-2", "aln": "MSTKQITCRYFMHGVCREGSQCLFSHDLANSKPSTICKYYQKGYCAYGTRCRYDHTRPSAAAGGAVGTMAH-SVPSPAFHSPHPPSEVTASIVKTNSHEPGKREKRTLVLRDRNLSGMAERKTQPSMVSNPGSCSDPQPSPEMKPHSYLDAIRSGLDDVEASSSYS--------NEQQLCPYAAAGECRFGDACVYLHGEVCEICRLQVLHPFDPEQRKAHEKICMLTFEHEMEKAFAFQASQDKVCSICMEVILEKASASERRFGILSNCNHTYCLSCIRQWRCAKQFENPIIKSCPECRVISEFVIPSVYWVEDQNKKNELIEAFKQGMGKKACKYFEQGKGTCPFGSKCLYRHAYPDGRLAEPEKPRKQLSSQGTVRFFNSVRLWDFIENRE---------SRHVPNNEDVDMTELGDLFMHLSGVESSEP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9ERV1-1", "uniprot_id": "MKRN2_MOUSE", "id": "Q9ERV1-1", "name": "E3 ubiquitin-protein ligase makorin-2", "aln": "MSTKQVTCRYFMHGVCREGSQCLFSHDLANSKPSTICKYYQKGYCAYGARCRYDHTKPPAAAGGAVGPAPN-PSPSSGLHSPHPSPDIATSVMRTHSNEPGKREKKTLVLRDRNLTGLAEDKTPPSKVNNPGGCSDPQTSPEMKPHSYLDAIRTGLDDLEASSSYS--------NEPQLCPYAAAGECRFGDACVYLHGDMCEICRLQVLHPFDPEQRKAHEKMCMSTFEHEMEKAFAFQASQDKVCSICMEVILEKASASERRFGILSNCSHTYCLSCIRQWRCAKQFENPIIKSCPECRVISEFVIPSVYWVEDQNKKNELIEAFKQGMGKKACKYFEQGKGTCPFGSKCLYRHAYPDGRLAEPEKPRKQLSSEGTVRFFNSVRLWDFIENRE---------TRQVPSTDDVDVTELGDLFMHLSGVESSEP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9DFG8-1", "uniprot_id": "MKRN2_DANRE", "id": "Q9DFG8-1", "name": "E3 ubiquitin-protein ligase makorin-2", "aln": "MSTKQVTCRYFLHGVCREGSRCLFSHDLTTSKPSTICKYYQRGACAYGDRCRYDHIKPPGRGSGAPADHSNRSSSSAGASAPGPGPPANTS----------KHLKKPLVLRDKALCSDSRPRVFSAESSELNECWEQRDDGAQKPHSYLEAIRSGLDASAAAAATAGTFPELQQTSPQICPFLAAGQCQYGESCPYLHGEMCEICRQHVLHPHDPEQRAAHEKKCMVAFEMDMERAFAVQQSQDKVCKICLDVVYEKSSPSERRFGILSSCAHTYCLNCIRQWRCVEQLHNQIRKSCPECRVVSEFVIPSIYWVEDQEQKNLLIEEFKSGVSKKACKYFDQGRGTCPFGGKCFYMHAYADGRRAEPDKPRKQLSAEGNVRFQNSVRLWDFIEERE---------HRSVPQLED-EVNDLGELFMQLSGASDAPH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * . . : : . :. *:** * **::.: :* . : *****..* * :*: ** ** . : :.****** *:** ** :*:: : *: *:. . .: : ****. * * * ** :*:* * :. ", "identical_positions": 46, "similar_positions": 42, "identity": "10.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020225-16", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LWD2-1", "uniprot_id": "A0ABK0LWD2_RAT", "id": "A0ABK0LWD2-1", "name": "Ig-like domain-containing protein", "aln": "MGMLL-QVLVGLLMFPAVWVNT-QKLQQSPQSLTIQEGDELTMSCNSS--SSLYALHWYRQGRDGGPIFLVTLQKGGDEKRKDKITAK----LDKKMRQSFLSIQASQPSYAGTYLCAGSAQWSIDCRGLSPNLQLGHSCSDTGPLRQD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A075B657-1", "uniprot_id": "A0A075B657_MOUSE", "id": "A0A075B657-1", "name": "", "aln": "MGMRL-QVLAWLLTFQAAWVNT-QMLHQSPQSLTIQEGDEVTMSCNLS--TSLYALLWYRQGDDGSLVSLVTLQKGGDEKSKDKITAN----LDKKMQQSSLWIQASQPSHSGTYLCGGK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J273-1", "uniprot_id": "TVA34_HUMAN", "id": "A0A0B4J273-1", "name": "T cell receptor alpha variable 34", "aln": "METVL-QVLLGILGFQAAWVSS-QELEQSPQSLIVQEGKNLTINCTSS--KTLYGLYWYKQKYGEGLIFLMMLQKGGEEKSHEKITAK----LDEKKQQSSLHITASQPSHAGIYLCGAD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5R1B6-1", "uniprot_id": "Q5R1B6_MOUSE", "id": "Q5R1B6-1", "name": "", "aln": "MNRFL-GISLVTLWFRVAWAKS-QWGEENLQALSIQEGEDVTMNCSYK--TYTTVVHWYRQDSGRGPALIILIRSNEREKRSGRLRAT----LDTSSQSSSLSITAAQCEDTAVYFCATD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B633-1", "uniprot_id": "A0A075B633_MOUSE", "id": "A0A075B633-1", "name": "", "aln": "MNRFL-GISLVTLWFQVAWAKS-QWGEENLQALSIQEGEDVTMNCSYK--TYTTVVQWYRQKSGKGPAQLILIRSNEREKRSGRLRAT----LDTSSQSSSLSITGTLATDTAVYFCATD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B641-1", "uniprot_id": "A0A075B641_MOUSE", "id": "A0A075B641-1", "name": "", "aln": "MHSLL-GLL---LWLQLTRVNS-QLAEENSWALSVHEGESVTVNCSYK--TSITALQWYRQKSGKGPAQLILIRSNEREKRNGRLRAT----LDTSSQSSSLSITATRCEDTAVYFCATD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5R1H8-1", "uniprot_id": "Q5R1H8_MOUSE", "id": "Q5R1H8-1", "name": "", "aln": "MHSLL-GLLMVSLWLQLTRVNS-QLAEENLWALSVHEGESVTVNCSYK--TSITALQWYRQKSGEGPAQLILIRSNEREKRNGRLRAT----LDTSSQSSSLSITATRCEDTAVYFCATD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J275-1", "uniprot_id": "TVA17_HUMAN", "id": "A0A0B4J275-1", "name": "T cell receptor alpha variable 17", "aln": "METLL-GVSLVILWLQLARVNS-QQGEEDPQALSIQEGENATMNCSYK--TSINNLQWYRQNSGRGLVHLILIRSNEREKHSGRLRVT----LDTSKKSSSLLITASRAADTASYFCATD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J279-1", "uniprot_id": "TVA21_HUMAN", "id": "A0A0B4J279-1", "name": "T cell receptor alpha variable 21", "aln": "METLL-GLLI--LWLQLQWVSSKQEVTQIPAALSVPEGENLVLNCSFTD-SAIYNLQWFRQDPGKGLTSLLLIQSSQREQTSGRLNAS----LDKSSGRSTLYIAASQPGDSATYLCAVR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J1J9-1", "uniprot_id": "A0A0B4J1J9_MOUSE", "id": "A0A0B4J1J9-1", "name": "", "aln": "MKKRL-SACWVVLWLHYQWVAGKTQVEQSPQSLVVRQGENCVLQCNYSV-TPDNHLRWFKQDTGKGLVSLTVLVDQKDKTSNGRYSAT----LDKDAKHSTLHITATLLDDTATYICVVG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J240-1", "uniprot_id": "TVA10_HUMAN", "id": "A0A0B4J240-1", "name": "T cell receptor alpha variable 10", "aln": "MKKHL-TTFLVILWLYFYRGNGKNQVEQSPQSLIILEGKNCTLQCNYTV-SPFSNLRWYKQDTGRGPVSLTIMTFSENTKSNGRYTAT----LDADTKQSSLHITASQLSDSASYICVVS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B6U4-1", "uniprot_id": "TVA7_HUMAN", "id": "A0A075B6U4-1", "name": "T cell receptor alpha variable 7", "aln": "MEKMR-RPVLIIFCLCLGWANGENQVEHSPHFLGPQQGDVASMSCTYSV-SRFNNLQWYRQNTGMGPKHLLSMYSAGYEKQKGRLNAT----LLKNG--SSLYITAVQPEDSATYFCAVD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J274-1", "uniprot_id": "TVA20_HUMAN", "id": "A0A0B4J274-1", "name": "T cell receptor alpha variable 20", "aln": "MEKML-ECAFIVLWLQLGWLSGEDQVTQSPEALRLQEGESSSLNCSYTV-SGLRGLFWYRQDPGKGPEFLFTLYSAGEEKEKERLKAT----LTKKE--SFLHITAPKPEDSATYLCAVQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B6V5-1", "uniprot_id": "TVA36_HUMAN", "id": "A0A075B6V5-1", "name": "T cell receptor alpha variable 36/delta variable 7", "aln": "MMKCP-QALLAIFWLLLSWVSSEDKVVQSPLSLVVHEGDTVTLNCSYEV-TNFRSLLWYKQE-KKAPTFLFMLTSSGIEKKSGRLSSI----LDKKELFSILNITATQTGDSAIYLCAVE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J272-1", "uniprot_id": "TVA24_HUMAN", "id": "A0A0B4J272-1", "name": "T cell receptor alpha variable 24", "aln": "MEKNPLAAPLLILWFHLDCVSSILNVEQSPQSLHVQEGDSTNFTCSFPS-SNFYALHWYRWETAKSPEALFVMTLNGDEKKKGRISAT----LNTKEGYSYLYIKGSQPEDSATYLCAF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B642-1", "uniprot_id": "A0A075B642_MOUSE", "id": "A0A075B642-1", "name": "", "aln": "-MKTSLHTVFLFLWLWMDWESHGEKVEQHESTLSVREGDSAVINCTYTD-TASSYFPWYKQEAGKSLHFVIDIRSNVDRKQSQRLIVL----LDKKAKRFSLHITATQPEDSAIYFCAAS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B622-1", "uniprot_id": "A0A075B622_MOUSE", "id": "A0A075B622-1", "name": "", "aln": "-MKTSLHTVFLFLWLWMDWESHGEKVEQHESTLSVREGDSAVINCTYTD-TASSYFPWYKQEAGKSLHFVIDIRSNVDRKQSQRLTVL----LDKKAKRFSLHITATQPEDSAIYFCAAS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5R1F6-1", "uniprot_id": "Q5R1F6_MOUSE", "id": "Q5R1F6-1", "name": "", "aln": "-MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYEN-SASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVL----LDKKAKRFSLHITDTQPGDSAMYFCAAS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B652-1", "uniprot_id": "A0A075B652_MOUSE", "id": "A0A075B652-1", "name": "", "aln": "-MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCSYED-SASNYFPWYKQEPGENPKLIIDIRSNMERKQIQELIVL----LDKKAKRFSLHITDTQPGDSAMYFCAAS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B5Z7-1", "uniprot_id": "A0A075B5Z7_MOUSE", "id": "A0A075B5Z7-1", "name": "", "aln": "-MKTAIHALFIFFWLQMDWKSQGEQVEQLPSSLIVQEGASVLINCSYTD-SASVYFPWYKQEPGKRLQFIIDIRSNMERKQTQRLTLL----FDKKTKHLSLHITATQPGDSAIYFCSAS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J249-1", "uniprot_id": "TVA5_HUMAN", "id": "A0A0B4J249-1", "name": "T cell receptor alpha variable 5", "aln": "-MKTFAGFSFLFLWLQLDCMSRGEDVEQS-LFLSVREGDSSVINCTYTD-SSSTYLYWYKQEPGAGLQLLTYIFSNMDMKQDQRLTVL----LNKKDKHLSLRIADTQTGDSAIYFCAES--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J241-1", "uniprot_id": "TVAM1_HUMAN", "id": "A0A0B4J241-1", "name": "T cell receptor alpha variable 13-1", "aln": "--MTSIRAVFIFLWLQLDLVN-GENVEQHPSTLSVQEGDSAVIKCTYSD-SASNYFPWYKQELGKGPQLIIDIRSNVGEKKDQRIAVT----LNKTAKHFSLHITETQPEDSAVYFCAAS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J235-1", "uniprot_id": "TVAM2_HUMAN", "id": "A0A0B4J235-1", "name": "T cell receptor alpha variable 13-2", "aln": "--MAGIRALFMYLWLQLDWVSRGESVGLHLPTLSVQEGDNSIINCAYSN-SASDYFIWYKQESGKGPQFIIDIRSNMDKRQGQRVTVL----LNKTVKHLSLQIAATQPGDSAVYFCAEN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B614-1", "uniprot_id": "A0A075B614_MOUSE", "id": "A0A075B614-1", "name": "", "aln": "----------------------GEQVEQRPPHLSVREGDSAVIICTYTD-PNSYYFFWYKQEPGAGLQLLMKVFSSTEINEGQGFTVL----LNKKDKQLSLNLTAAHPGDSAVYFCAV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B5Z4-1", "uniprot_id": "A0A075B5Z4_MOUSE", "id": "A0A075B5Z4-1", "name": "", "aln": "----MLQMWGFVLYLFLTVGGAAGQGVEQPAKLMSVEGTFARVNCTYST-SGFNGLSWYQQREGQAPVFLSYVVLDG-LKDSGHFSTF----LSRSNGYSYLLLTELQIKDSASYLCAVR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5R1I9-1", "uniprot_id": "Q5R1I9_MOUSE", "id": "Q5R1I9-1", "name": "", "aln": "------MKQVAKVTVLLILVSWSLAKTTQPPSMEAYEGQEVNVSCSHTNIATSEYIYWYRQVPHQGPQFIIQGYKDYVVNEVASLFIS----ADRKL--STLSLPWVSLRDAAVYYCIVTD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B6C4-1", "uniprot_id": "A0A075B6C4_MOUSE", "id": "A0A075B6C4-1", "name": "", "aln": "------MGCVSGIAILLALGIAGDAKTTQPDSMESTEGETVHLPCSHATISGNEYIYWYRQVPLQGPEYVTHGLQQNTTNSMAFLAIA----SDRKS--STLILPHVSLRDAAVYHCILRV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VTQ5-1", "uniprot_id": "Q5VTQ5_DANRE", "id": "Q5VTQ5-1", "name": "", "aln": "-----MRYYFIVLLSSTIFCSIGFDVVQEDNVKIVEAGEDVNFTCKFPE-LVQSINAWFKQTTDGKSLQIVSSYLNQQPSWNHNFEKTNRFIVANENGYFNLTIFKTKPLDSATYYCVISAYQTIGMGSGTRLLVGDSATDRNSTLHQSLIDTVDPGDSVNLQCSIFTESCAGDHSVYWFKQSSGDSEGVLYTKGERNGRCKNSTESQTQSCVYSLHKNNISRSDSGIYYCALAACGQILLGRGTQLNIRESDAVNPTLIALGILNVIFLVYAVFVTIELRNKVRLDICGEDILILADQNDLIAGLNVKFSEEHSFVKYSMIMQKNAYKTLQAIRSST", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * *:: : * : :. * * ", "identical_positions": 6, "similar_positions": 7, "identity": "1.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020225-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A075B642-1", "uniprot_id": "A0A075B642_MOUSE", "id": "A0A075B642-1", "name": "", "aln": "----------------------------------------------------MKTSLHTVFLFLWLWMDWESHGEKVEQHESTLSVRE-----------------------------------------------------------GDSAVINCTYTD---TASSYFPWYKQEAGKSLHFVIDIRSNVDRKQSQRLIVLLDKKAKRFSLHITATQPEDSAIYFCAAS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B622-1", "uniprot_id": "A0A075B622_MOUSE", "id": "A0A075B622-1", "name": "", "aln": "----------------------------------------------------MKTSLHTVFLFLWLWMDWESHGEKVEQHESTLSVRE-----------------------------------------------------------GDSAVINCTYTD---TASSYFPWYKQEAGKSLHFVIDIRSNVDRKQSQRLTVLLDKKAKRFSLHITATQPEDSAIYFCAAS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5R1F6-1", "uniprot_id": "Q5R1F6_MOUSE", "id": "Q5R1F6-1", "name": "", "aln": "----------------------------------------------------MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQE-----------------------------------------------------------GSSASINCTYEN---SASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B652-1", "uniprot_id": "A0A075B652_MOUSE", "id": "A0A075B652-1", "name": "", "aln": "----------------------------------------------------MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQE-----------------------------------------------------------GSSASINCSYED---SASNYFPWYKQEPGENPKLIIDIRSNMERKQIQELIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B5Z7-1", "uniprot_id": "A0A075B5Z7_MOUSE", "id": "A0A075B5Z7-1", "name": "", "aln": "----------------------------------------------------MKTAIHALFIFFWLQMDWKSQGEQVEQLPSSLIVQE-----------------------------------------------------------GASVLINCSYTD---SASVYFPWYKQEPGKRLQFIIDIRSNMERKQTQRLTLLFDKKTKHLSLHITATQPGDSAIYFCSAS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J249-1", "uniprot_id": "TVA5_HUMAN", "id": "A0A0B4J249-1", "name": "T cell receptor alpha variable 5", "aln": "----------------------------------------------------MKTFAGFSFLFLWLQLDCMSRGEDVEQS-LFLSVRE-----------------------------------------------------------GDSSVINCTYTD---SSSTYLYWYKQEPGAGLQLLTYIFSNMDMKQDQRLTVLLNKKDKHLSLRIADTQTGDSAIYFCAES-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J241-1", "uniprot_id": "TVAM1_HUMAN", "id": "A0A0B4J241-1", "name": "T cell receptor alpha variable 13-1", "aln": "-----------------------------------------------------MTSIRAVFIFLWLQLDLVN-GENVEQHPSTLSVQE-----------------------------------------------------------GDSAVIKCTYSD---SASNYFPWYKQELGKGPQLIIDIRSNVGEKKDQRIAVTLNKTAKHFSLHITETQPEDSAVYFCAAS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J235-1", "uniprot_id": "TVAM2_HUMAN", "id": "A0A0B4J235-1", "name": "T cell receptor alpha variable 13-2", "aln": "-----------------------------------------------------MAGIRALFMYLWLQLDWVSRGESVGLHLPTLSVQE-----------------------------------------------------------GDNSIINCAYSN---SASDYFIWYKQESGKGPQFIIDIRSNMDKRQGQRVTVLLNKTVKHLSLQIAATQPGDSAVYFCAEN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B614-1", "uniprot_id": "A0A075B614_MOUSE", "id": "A0A075B614-1", "name": "", "aln": "-------------------------------------------------------------------------GEQVEQRPPHLSVRE-----------------------------------------------------------GDSAVIICTYTD---PNSYYFFWYKQEPGAGLQLLMKVFSSTEINEGQGFTVLLNKKDKQLSLNLTAAHPGDSAVYFCAV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J273-1", "uniprot_id": "TVA34_HUMAN", "id": "A0A0B4J273-1", "name": "T cell receptor alpha variable 34", "aln": "---------------------------------------------------METVL-QVLLGILGFQAAWVSS-QELEQSPQSLIVQE-----------------------------------------------------------GKNLTINCTSS----KTLYGLYWYKQKYGEGLIFLMMLQKGGEEKSHEKITAKLDEKKQQSSLHITASQPSHAGIYLCGAD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B657-1", "uniprot_id": "A0A075B657_MOUSE", "id": "A0A075B657-1", "name": "", "aln": "---------------------------------------------------MGMRL-QVLAWLLTFQAAWVNT-QMLHQSPQSLTIQE-----------------------------------------------------------GDEVTMSCNLS----TSLYALLWYRQGDDGSLVSLVTLQKGGDEKSKDKITANLDKKMQQSSLWIQASQPSHSGTYLCGGK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5R1B6-1", "uniprot_id": "Q5R1B6_MOUSE", "id": "Q5R1B6-1", "name": "", "aln": "---------------------------------------------------MNRFL-GISLVTLWFRVAWAKS-QWGEENLQALSIQE-----------------------------------------------------------GEDVTMNCSYK----TYTTVVHWYRQDSGRGPALIILIRSNEREKRSGRLRATLDTSSQSSSLSITAAQCEDTAVYFCATD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B633-1", "uniprot_id": "A0A075B633_MOUSE", "id": "A0A075B633-1", "name": "", "aln": "---------------------------------------------------MNRFL-GISLVTLWFQVAWAKS-QWGEENLQALSIQE-----------------------------------------------------------GEDVTMNCSYK----TYTTVVQWYRQKSGKGPAQLILIRSNEREKRSGRLRATLDTSSQSSSLSITGTLATDTAVYFCATD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B641-1", "uniprot_id": "A0A075B641_MOUSE", "id": "A0A075B641-1", "name": "", "aln": "---------------------------------------------------MHSLL-GLL---LWLQLTRVNS-QLAEENSWALSVHE-----------------------------------------------------------GESVTVNCSYK----TSITALQWYRQKSGKGPAQLILIRSNEREKRNGRLRATLDTSSQSSSLSITATRCEDTAVYFCATD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5R1H8-1", "uniprot_id": "Q5R1H8_MOUSE", "id": "Q5R1H8-1", "name": "", "aln": "---------------------------------------------------MHSLL-GLLMVSLWLQLTRVNS-QLAEENLWALSVHE-----------------------------------------------------------GESVTVNCSYK----TSITALQWYRQKSGEGPAQLILIRSNEREKRNGRLRATLDTSSQSSSLSITATRCEDTAVYFCATD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J275-1", "uniprot_id": "TVA17_HUMAN", "id": "A0A0B4J275-1", "name": "T cell receptor alpha variable 17", "aln": "---------------------------------------------------METLL-GVSLVILWLQLARVNS-QQGEEDPQALSIQE-----------------------------------------------------------GENATMNCSYK----TSINNLQWYRQNSGRGLVHLILIRSNEREKHSGRLRVTLDTSKKSSSLLITASRAADTASYFCATD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J279-1", "uniprot_id": "TVA21_HUMAN", "id": "A0A0B4J279-1", "name": "T cell receptor alpha variable 21", "aln": "---------------------------------------------------METLL-GLLI--LWLQLQWVSSKQEVTQIPAALSVPE-----------------------------------------------------------GENLVLNCSFTD---SAIYNLQWFRQDPGKGLTSLLLIQSSQREQTSGRLNASLDKSSGRSTLYIAASQPGDSATYLCAVR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B6U4-1", "uniprot_id": "TVA7_HUMAN", "id": "A0A075B6U4-1", "name": "T cell receptor alpha variable 7", "aln": "---------------------------------------------------MEKMR-RPVLIIFCLCLGWANGENQVEHSPHFLGPQQ-----------------------------------------------------------GDVASMSCTYSV---SRFNNLQWYRQNTGMGPKHLLSMYSAGYEKQKGRLNATLLKNG--SSLYITAVQPEDSATYFCAVD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J274-1", "uniprot_id": "TVA20_HUMAN", "id": "A0A0B4J274-1", "name": "T cell receptor alpha variable 20", "aln": "---------------------------------------------------MEKML-ECAFIVLWLQLGWLSGEDQVTQSPEALRLQE-----------------------------------------------------------GESSSLNCSYTV---SGLRGLFWYRQDPGKGPEFLFTLYSAGEEKEKERLKATLTKKE--SFLHITAPKPEDSATYLCAVQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B6V5-1", "uniprot_id": "TVA36_HUMAN", "id": "A0A075B6V5-1", "name": "T cell receptor alpha variable 36/delta variable 7", "aln": "---------------------------------------------------MMKCP-QALLAIFWLLLSWVSSEDKVVQSPLSLVVHE-----------------------------------------------------------GDTVTLNCSYEV---TNFRSLLWYKQE-KKAPTFLFMLTSSGIEKKSGRLSSILDKKELFSILNITATQTGDSAIYLCAVE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J272-1", "uniprot_id": "TVA24_HUMAN", "id": "A0A0B4J272-1", "name": "T cell receptor alpha variable 24", "aln": "---------------------------------------------------MEKNPLAAPLLILWFHLDCVSSILNVEQSPQSLHVQE-----------------------------------------------------------GDSTNFTCSFPS---SNFYALHWYRWETAKSPEALFVMTLNGDEKKKGRISATLNTKEGYSYLYIKGSQPEDSATYLCAF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J1J9-1", "uniprot_id": "A0A0B4J1J9_MOUSE", "id": "A0A0B4J1J9-1", "name": "", "aln": "---------------------------------------------------MKKRL-SACWVVLWLHYQWVAGKTQVEQSPQSLVVRQ-----------------------------------------------------------GENCVLQCNYSV---TPDNHLRWFKQDTGKGLVSLTVLVDQKDKTSNGRYSATLDKDAKHSTLHITATLLDDTATYICVVG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J240-1", "uniprot_id": "TVA10_HUMAN", "id": "A0A0B4J240-1", "name": "T cell receptor alpha variable 10", "aln": "---------------------------------------------------MKKHL-TTFLVILWLYFYRGNGKNQVEQSPQSLIILE-----------------------------------------------------------GKNCTLQCNYTV---SPFSNLRWYKQDTGRGPVSLTIMTFSENTKSNGRYTATLDADTKQSSLHITASQLSDSASYICVVS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B5Z4-1", "uniprot_id": "A0A075B5Z4_MOUSE", "id": "A0A075B5Z4-1", "name": "", "aln": "-------------------------------------------------------MLQMWGFVLYLFLTVGGAAGQGVEQPAKLMSVE-----------------------------------------------------------GTFARVNCTYST---SGFNGLSWYQQREGQAPVFLSYVVLDG-LKDSGHFSTFLSRSNGYSYLLLTELQIKDSASYLCAVR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5R1I9-1", "uniprot_id": "Q5R1I9_MOUSE", "id": "Q5R1I9-1", "name": "", "aln": "---------------------------------------------------------MKQVAKVTVLLILVSWSLAKTTQPPSMEAYE-----------------------------------------------------------GQEVNVSCSHTNI--ATSEYIYWYRQVPHQGPQFIIQGYKDYVVNEVASLFISADRKL--STLSLPWVSLRDAAVYYCIVTD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A075B6C4-1", "uniprot_id": "A0A075B6C4_MOUSE", "id": "A0A075B6C4-1", "name": "", "aln": "---------------------------------------------------------MGCVSGIAILLALGIAGDAKTTQPDSMESTE-----------------------------------------------------------GETVHLPCSHATI--SGNEYIYWYRQVPLQGPEYVTHGLQQNTTNSMAFLAIASDRKS--STLILPHVSLRDAAVYHCILRV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QG83-1", "uniprot_id": "F1QG83_DANRE", "id": "F1QG83-1", "name": "", "aln": "MRYYFILLSSTIFCSFGVEVVQENNVKIAAAGEDVNLPCTFSRLLQATKAWFKQTADGKSLQIVSLYLDQIPNWNNNSENGFNIMKEDGYFNLTILKTKPSDSATYYCVISTAYNIGMGSGTRLFVRDSAKDRNTTLHQSLIDTVDPGDSVNLQCSIFTESCAGDHSVYWFKQSSGDSE---GVLYTKGERNGRCKDSTESQTQSCVYSLHKNNISRSDSGIYYCAVASCGEILLGRGTQLNIRESGHLYPGLLALFGVLNIIFLALAVFLGFKLFRGQRKTQESLNQDSLNYAAITFRQKPLNTKRARAQITQEQSLYAQVRSLQ---------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I5ZUS5-1", "uniprot_id": "A0A8I5ZUS5_RAT", "id": "A0A8I5ZUS5-1", "name": "", "aln": "---------------------------------------------MLLLHSSAHILHSALLLILLLELKGADMKELKVIQPQKLVSVYD----------------------------------------------------------GGSVILNCTVTS--LTPVGPTRWFKGE-GQNRQLIYSFRGDYFPRITN-IADVTKRNNTDFSIRISNIMLADAGTYYCVKFQKGTVEPDIEIQSGGGTELFVYGADMKKLKVVQPEKLISVDAGESVTLNCTVTSIIPMGPIKWFRGAQHSRHLIFNFTGGYFPRVTNVSDSSKRNNLDFSIRISNVMPADAGTYYCVKFQKELLETDIEIQSGGGTELLVFEPKTSGIAKILAAALLGYKLMLVIAVTLIHKHRCKIPE", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . * *:: : .:. * * ", "identical_positions": 5, "similar_positions": 8, "identity": "1.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020228-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2YDU8-1", "uniprot_id": "SPNS1_RAT", "id": "Q2YDU8-1", "name": "Protein spinster homolog 1", "aln": "---------------MAGSDTAPFLSQADDPDDGPAPGH-----------PGLPGPMGNPKSGELEVPDCEG-----------------LQRITGLSR------------GHSTLIVVVLCYINLLNYMDRFTVAGVLTDIEQFFNIGDGSTGLIQTVFISSYMVLAPVFGYLGDRYNRKYLMCGGIAFWSLVTLGSSFIPREHFWLLLLTRGLVGVGEASYSTIAPTLIADLFVADQRSRMLSIFYFAIPVGSGLGYIAGSKVKDLAGDWHWALRVTPGLGVLAVLLLFLVVQEPPRGAVERHSGSPPLSPTSWWADLKALARNPSFVLSSLGFTAVAFVTGSLALWAPAFLLRSRVVLGETPPCLPGDSCSSSDSLIFGLITCLTGVLGVGLGVEISRRLRRFNPRADPLVCAAGLLGSSPFLFLSLACARGSIVATYIFIFIGETLLSMNWAIVADILLYVVIPTRRSTAEAFQIVLSHLLGDAGSPYLIGLISDRLR------------------------------------------------RSWPPSFLSEFRALQFSLMLCAFVGALGGAAFLGTAMFIENDRRRAQLHVQGLLHETEPSDDQIVVPQRGRSTRVPVSSVLI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0G7-1", "uniprot_id": "SPNS1_MOUSE", "id": "Q8R0G7-1", "name": "Protein spinster homolog 1", "aln": "---------------MAGSDTAPFLSQADDPDDGPAPGH-----------PGLPGPMGNPKSGELEVPDCEG-----------------LQRITGLSR------------GHSTLIVVVLCYINLLNYMDRFTVAGVLTDIEQFFNIGDGSTGLIQTVFISSYMVLAPVFGYLGDRYNRKYLMCGGIAFWSLVTLGSSFIPREHFWLLLLTRGLVGVGEASYSTIAPTLIADLFVADQRSRMLSIFYFAIPVGSGLGYIAGSKVKDVAGDWHWALRVTPGLGVLAVLLLFLVVQEPPRGAVERHSGSPPLSPTSWWADLKALARNPSFVLSSLGFTSVAFVTGSLALWAPAFLLRSRVVLGETPPCLPGDSCSSSDSLIFGLITCLTGVLGVGLGVEISRRLRRFNPRADPLVCAAGLLGSAPFLFLALACARGSIVATYIFIFIGETLLSMNWAIVADILLYVVIPTRRSTAEAFQIVLSHLLGDAGSPYLIGLISDRLR------------------------------------------------RSWPPSFLSEFRALQFSLMLCAFVGALGGAAFLGTAMFIEDDRRRAQLHVQGLLHESGPSDDRIVVPQRGRSTRVPVSSVLI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2V7-1", "uniprot_id": "SPNS1_HUMAN", "id": "Q9H2V7-1", "name": "Protein spinster homolog 1", "aln": "---------------MAGSDTAPFLSQADDPDDGPVPGT-----------PGLPGSTGNPKSEEPEVPDQEG-----------------LQRITGLSP------------GRSALIVAVLCYINLLNYMDRFTVAGVLPDIEQFFNIGDSSSGLIQTVFISSYMVLAPVFGYLGDRYNRKYLMCGGIAFWSLVTLGSSFIPGEHFWLLLLTRGLVGVGEASYSTIAPTLIADLFVADQRSRMLSIFYFAIPVGSGLGYIAGSKVKDMAGDWHWALRVTPGLGVVAVLLLFLVVREPPRGAVERHSDLPPLNPTSWWADLRALARNPSFVLSSLGFTAVAFVTGSLALWAPAFLLRSRVVLGETPPCLPGDSCSSSDSLIFGLITCLTGVLGVGLGVEISRRLRHSNPRADPLVCATGLLGSAPFLFLSLACARGSIVATYIFIFIGETLLSMNWAIVADILLYVVIPTRRSTAEAFQIVLSHLLGDAGSPYLIGLISDRLR------------------------------------------------RNWPPSFLSEFRALQFSLMLCAFVGALGGAAFLGTAIFIEADRRRAQLHVQGLLHEAGSTDDRIVVPQRGRSTRVPVASVLI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZU13-1", "uniprot_id": "SPNS1_DANRE", "id": "Q7ZU13-1", "name": "Protein spinster homolog 1", "aln": "-------------MSQADADITPFFADDNE-GEGPVENG-----------VGSP----LPEDEEEESP-------------------------SGVTD------------RRAIMTVIVLCYINLLNYMDRFTVAGVLPDIEHFFGIGDGTSGLLQTVFICSYMFLAPLFGYLGDRYNRKLIMCVGIFFWSVVTLASSFIGKDHFWALLLTRGLVGVGEASYSTIAPTIIADLFVKEKRTNMLSIFYFAIPVGSGMGYIVGSKVDTVAKDWHWALRVTPGLGLLAVFLLMLVVQEPKRGAIEAHP-EHTLHRTSWLADMKALCRNPSFILSTFGFTAVAFVTGSLALWAPAFLFRAGVFTGVKQPCFKAP-CDDSDSLIFGAITVVTGILGVASGVQASKLLRTRTPRADPLVCAAGLLLAAPFLYLSIMFAQASTVATYVFIFLGETFLSMNWAIVADILLYVVIPTRRSTAEAFQIVLSHLLGDAISPYLIGVVSDSIK------------------------------------------------ESN--SYMWEFRSLQMSLLLCSFVAVAGGAFFLATAVFIEKDRDLAENYVP-------SDDAPIVVPRSGRSTKVSVSSVLI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9GQQ0-1", "uniprot_id": "SPIN_DROME", "id": "Q9GQQ0-1", "name": "Protein spinster", "aln": "MSLKHQKQSYQPLPTAAAMDNPAMIQSSGSSGSSSSEEGGSREDVANLSPLGLPTTYSSQQLMPSDTDSMEEERHRLRPHHHHHHPLGEHHHIPGIPPSAVVPSRLSSVGRSQWFTVTVLCFVNLINYMDRFTIAGVLTDVRNDFDIGNDSAGLLQTVFVISYMVCAPIFGYLGDRYSRPWIMAVGVGLWSTTTLLGSFMK--QFGWFIAFRALVGIGEASYSTIAPTIISDLFVHDMRSKMLALFYFAIPVGSGLGYIVGSKTAHLANDWRWALRVTPILGIVAVFLILLIK-DPVRG---HSEGSHNLEATTYKQDIKALVRNRSFMLSTAGFTCVAFVAGALAWWGPSFIY-----LGMKMQPGNENIVQDDVAFNFGVITMLAGLLGVPLGSFLSQYLVKRYPTADPVICAFGLLVSAPLLTGACLLVNSNSVGTYALIFFGQLALNLNWAIVADILLYVVVPTRRSTAEAFQILISHALGDAGSPYLVGAISEAIMKHLHKNPSDSGLTTELRSMSQVAGSAISNATQVIAEATTSLMETARSSASQEYSDVEQFEGLQYALFSTSFVEVLGGIFFIFTACFIIKDKYNATRGLQ-----------DATAQQQQRDERGQIA----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * ..:: . .. .... * * : : .*:. : * ***::**:*******:****.*:.: *.**:.::**:****: ***. **:********.* :*. *: :** .** .**: :* :: *.***:***********:*:**** : *:.**::**********:***.***. :* **:******* **::**:*::*: :* ** * *:: *::** ** **:**: ***.****:*:** *.*:*: * . ... :: ** ** ::*:*** * *: * * ***::** *** ::*:* : .... *.** :**:*: *.:*************:************::** **** ****:* :*: : . * : :*..** :*: :** . ** *: ** ** *: * : .. : *. : :: ", "identical_positions": 221, "similar_positions": 130, "identity": "35.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020228-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZIF4-1", "uniprot_id": "D3ZIF4_RAT", "id": "D3ZIF4-1", "name": "Sal-like protein 1", "aln": "---------MSRRKQAKPQHFQSDPEVASLPRRDGDTEKGQPSRPTKSKDAHVCGRCCAEFFELSDLLLHKKSCTKNQLVLIVNESPASPPKTFPPGPPSLNNPDEQMKFVASKADQEDCGDLSEHKGLDREESMETEVPVATSSSSSNGG-------TLSSVTNIATPSCHSGSSTGTSAITTSLPQLGDLTTLGNFSVINSNVIIENLQSTKVAVAQFSQEARCG-----GASGGKLLISALMEQLLALQQQQIHQLQLIEQIRHQILLLAS-QNADLSAS-SVPSQGTLRTSANPLTTLSSHLSQQLAVAAGLAQSLASQSANISGVKQLP-PVQLPQSSSGT-IIPPSSGPSPNVSMVTATVPTPSSEKVASNAGASH--VSPPAVSASSSPAAFAISSLLSPASNPLLPQPTPANAVFPTPLPNIATTAEDLNALSALAQQRKSKPPNVTAFEAKSTSDEAFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEHLDN-VPTSTGIPYGMSIPPEKPVTSWLD---TKPVLPTLTTSVGLPLP-----------------------------PTLPSLTPFIKTE-------------------EPAPIPISHSAASPQGSVKSDSGAPDLATRNPSGVPEEAEGSAVPPFGGKGEDSSVVS-SIPTAGSSALNSPVADGGAGG--TTFTNPLLP------------------------------------------------------------------LMSEQFKAKFPFGGLLDSAQASETSKLQQLVENIDKKATDPNECVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPVPDNYPESMESDTGSFDEKNFDDLDNFSDENME---ECPEGSIPDTPKSADASQDSLSSSPLPLEMSSIAALENQMKMINAGLAEQLQAS-LKSVENGSVEGDVLTNDSS--SVGGDVESQSSGSPAISESTSSMQALSPSNSTQEFHKSPNVEEKPQRVGPGEFANG--LSPTPVNGGALDLTSSHAEKIIKEDSLGILFPFRDRGKFKN----TACDICGKTFACQSALDIHYRSHTKERPFI-------CTVCSRGFSTKGNLKQHMLT------------HQMRDLPSQLFEP----SSNLGPNQNSAMIPASSLSSLIKTEVNGFVHVSPQDSKDAPTSHVPSGPLSSSATSP-------VLLPALPRR-----TPKQHYCNTCGKTFSSSSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHMGTHMWNSTPARRGRRLSVDGPMT-----------------FLGGNP---VKFPEMFQKDLAARSGSGDPSSFWNQYTAALSNGLAMKANEISVIQNGGIPP-IPGSLGNGSSSPISGLTGNVEKLGNSEPSAPLAGLEKMASSENGTNFRFTRFVEDSKEIVTS----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER74-1", "uniprot_id": "SALL1_MOUSE", "id": "Q9ER74-1", "name": "Sal-like protein 1", "aln": "---------MSRRKQAKPQHFQSDPEVASLPRRDGDTEKGQPSRPTKSKDAHVCGRCCAEFFELSDLLLHKKSCTKNQLVLIVNESPASPAKTFPPGP-SLNDPDDQMKDAANKADQEDCSDLSEPKGLDREESMEVEVPVATTTTTTTGGSGGSGGSTLSGVTNITTPSCHSGCSSGTSAITTSLPQLGDLTTLGNFSVINSNVIIENLQSTKVAVAQFSQEARCG-----GASGGKLLISTLMEQLLALQQQQIHQLQLIEQIRHQILLLAS-QSADLPAAPSIPSQGTLRTSANPLTTLSSHLSQQLAVAAGLAQSLASQSANISGVKQLP-HVQLPQSSSGTSIVPPSGGTSPNMSIVTAAVPTPSSEKVASNAGASH--VSSPAVSASSSP-AFAISSLLSPESNPLLPQPTPANAVFPTPLPNIATTAEDLNSLSALAQQRKSKPPNVTAFEAKSTSDEAFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEHLDN-VPTSTGIPYGMSIPSEKPVTSWLD---TKPVLPTLTTSVGLPLP-----------------------------PTLPSLTPFIKTE-------------------EPAPIPISHSAASPQGSVKSDSGAPDLATRNPSGVPEEVEGSAVPPFGGKGEESNMASSAVPTAGNSTLNSPVADGGPGG--TTFTNPLLP------------------------------------------------------------------LMSEQFKAKFPFGGLLDSAQASETSKLQQLVENIDKKATDPNECIICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPVPDNYPESMESDTGSFDEKNFDDLDNFSDENME---ECPEGSIPDTPKSADASQDSLSSSPLPLEMSSIAALENQMKMINAGLAEQLQAS-LKSVENGSMEGDVLTNDSS--SVGGDMESQSAGSPAISESTSSMQALSPSNSTQEFHKSPGMEEKPQRVGPGEFANG--LSPTPVNGGALDLTSSHAEKIIKEDSLGILFPFRDRGKFKN----TACDICGKTFACQSALDIHYRSHTKERPFI-------CTVCNRGFSTKGNLKQHMLT------------HQMRDLPSQLFEP----SSNLGPNQNSAVIPANSLSSLIKTEVNGFVHVSPQDSKDAPTSHVPQGPLSSSATSP-------VLLPALPRR-----TPKQHYCNTCGKTFSSSSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHMGTHMWNSTPARRGRRLSVDGPMT-----------------FLGGNP---VKFPEMFQKDLAARSGSGDPSSFWNQYTAALSNGLAMKANEISVIQNGGIPP-IPGSLGSGSS-PISGLTGNVEKLGNSEPSAPLAGLEKMASSENGTNFRFTRFVEDSKEIVTS----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NSC2-1", "uniprot_id": "SALL1_HUMAN", "id": "Q9NSC2-1", "name": "Sal-like protein 1", "aln": "---------MSRRKQAKPQHFQSDPEVASLPRRDGDTEKGQPSRPTKSKDAHVCGRCCAEFFELSDLLLHKKNCTKNQLVLIVNENPASPPETFSPSP-PPDNPDEQMNDTVNKTDQVDCSDLSEHNGLDREESMEVEAPVANKSGSGTSSGSHSSTAPSSSSSSSSSSGGGGSSSTGTSAITTSLPQLGDLTTLGNFSVINSNVIIENLQSTKVAVAQFSQEARCG-----GASGGKLAVPALMEQLLALQQQQIHQLQLIEQIRHQILLLAS-QNADLPTS-SSPSQGTLRTSANPLSTLSSHLSQQLAAAAGLAQSLASQSASISGVKQLP-PIQLPQSSSGNTIIPSNSGSSPNMNILAAAVTTPSSEKVASSAGASH--VSNPAVSSSSSP-AFAISSLLSPASNPLLPQQASANSVFPSPLPNIGTTAEDLNSLSALAQQRKSKPPNVTAFEAKSTSDEAFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEHLDN-IPTSTGIPYGMSIPPEKPVTSWLD---TKPVLPTLTTSVGLPLP-----------------------------PTLPSLIPFIKTE-------------------EPAPIPISHSATSPPGSVKSDSGGPESATRNLGGLPEEAEGSTLPPSGGKSEESGMVTNSVPTASSSVLSSPAADCGPAGSATTFTNPLLP------------------------------------------------------------------LMSEQFKAKFPFGGLLDSAQASETSKLQQLVENIDKKATDPNECIICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPVPDSYSESMESDTGSFDEKNFDDLDNFSDENME---DCPEGSIPDTPKSADASQDSLSSSPLPLEMSSIAALENQMKMINAGLAEQLQAS-LKSVENGSIEGDVLTNDSS--SVGGDMESQSAGSPAISESTSSMQALSPSNSTQEFHKSPSIEEKPQRAVPSEFANG--LSPTPVNGGALDLTSSHAEKIIKEDSLGILFPFRDRGKFKN----TACDICGKTFACQSALDIHYRSHTKERPFI-------CTVCNRGFSTKGNLKQHMLT------------HQMRDLPSQLFEP----SSNLGPNQNSAVIPANSLSSLIKTEVNGFVHVSPQDSKDTPTSHVPSGPLSSSATSP-------VLLPALPRR-----TPKQHYCNTCGKTFSSSSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHMGTHMWNSTPARRGRRLSVDGPMT-----------------FLGGNP---VKFPEMFQKDLAARSGSGDPSSFWNQYAAALSNGLAMKANEISVIQNGGIPP-IPGSLGSGNSSPVSGLTGNLERLQNSEPNAPLAGLEKMASSENGTNFRFTRFVEDSKEIVTS----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QI36-1", "uniprot_id": "F1QI36_DANRE", "id": "F1QI36-1", "name": "Sal-like protein 1", "aln": "---------MSRRKQAKPQHFQSDSQLV-LAEHNGDTETNPDDSPCKDSGAHVCSRCCAEFFELSDLEQHQKNCTKNQLVLIVNENPVSPSGTFSPGS-SPHNPDEQMNDTTNNTDQAELTDLLEQNILDKEEAMDTEMSGVSAPHN-DGNGRMAGSSPLSGVGTGHGTLGSTGSNLGSSVISASLPQLGNLTELGNFSMINSNVIIENLQSTKVAVAQFSQETRAT-----GGQ--RVAVPALMEQLLALQQQQIHQLQLIEQIRHQILLLAS-QSPELQAP-PSSSPVTLGSGTSPLTTLSSHLSQQLAAAAGLAQSIASQSASISSLKQMANVAQLPQSNSSVGESSQSLAAPG-----PAPVNAQPLEKRPGNAGSLHPPLGNPSLAKSSTP-AFAMGNLLNPVANTLLPQPPPGNPIFSSALPSVGSTVEDLNSLAALAQQRKGKPPNVSSFEPKSSSEDTFFKHKCRFCGKVFGSDSALQIHLRSHTGERPYKCNICGNRFSTRGNLKVHFQRHKEKYPHIQMNPYPVPEHLDN-IPTSTGIPYGMSMPPEKPVTSWLD---SKPVLSTLTSSVGMLLP-----------------------------PTIPSLPPFIKKE-------------------ENNSLAIS----SPSHSAKSDSGPADTPMKNTDSVLEEGESTTLPTSNGKAEENNQSSNLLSNMSSAVEGTIEYTTSNSP--PMATNPLMP------------------------------------------------------------------LMSEQFKAKFPFGGLLDPLQGSETSKLQQLVENIDRKVADPNECVICHRILSCQSALKMHYRTHTGERPFKCKVCGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPDNYPESMGSDAGSFDERNIDDLDNFSDDNMEGIEDGPDSSIPDTPKSVDASQDSLCSSPT-LHESFGMDERIQEKSANHGAGEEVQYDQGKSVENGLVEGDRFTNDSS--SLGGDIESQSAGSPAVSESTSSMQAPSPSNGIFQQQKSPSMEDRQQRALSLEHISASLMHSNSASPGALDLTSVNSSK----DPISMLFPFRERGTLKN----TACDICGKTFACQSALDIHYRSHTKERPFI-------CTVCNRGFSTKGNLKQHMLT------------HQMRDLPSQLFEPNTSLASSLASSPTPSLLSVGPLSSMMKTEVNGFLHGLQPEVKDLPPALVT----SSASTSP-------VLSAAPPRR-----TPKQHFCTTCGKTFSSSSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHMGTHMWNSAPARRGRRLSVDGPMA-----------------FLGTNP---VKFPELFQKDLSSRAGNGDPTSFWNQYAAAFSNGLAMKTNEISVIQNGGLPPPLSGSVGNGGSSPIGGLTGSMEKLHNSEPNPALAGLEKMANTENGTHFRFTRFMED-KEIVTN----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKH3-1", "uniprot_id": "Q9VKH3_DROME", "id": "Q9VKH3-1", "name": "", "aln": "---------MCSIFRNRINYRGTGGTRSGSGERERDRDRDRD---------------------------RDRDRERDRDTLLAKELDAD----------SNNNGTEPQMEAEAVPESDTERETAEERGEEQE------------------------------------------PENSNEALDLSLISSGGRESLP----GSGHVSLEALQHTKVAVAQFAATAMAG-----NHQSADLAM--VQSTIFNVQRQHLMQLQLIQHLQSQLKRAEA-AALGRHSH-SDEEEEEPEPEPEPKKQPTNGLKEELELEQGPESEQDQESRREENSKTDK---------------------------------RGTEDRKAEPEGYQS------MMCDISSS-------LASSIITNHDPPPAPNEPNCLEMLQRRTEEVLDSASQSLHAAQMQEEYSEYASKEAQSRGE--IFKHRCKYCGKIFGSYSALQIHLRSHTGERPFVCNVCGSKFTTKGNLKVHYQRHTQIFPPMLLPPGVAPNVGHSGQGQVQGEQYPIRLPFAPPVAPVGQEQHQNQVEEPEEIRQEIPVP-----------------------------QAEDLSKPMVKEK-------------------EKSHSPVER--VKTPKEVKTDAALPSSEKPEKEISKPVVTSSRRNGSVRKRQTSAVSPPQEDRERDLVEHLHIAKLVRRSSASRESQPAEYS-----------------------------------------------------------------LAQMERIIDKSWEDLIEIDKTSETSKLQQLVDNIENKLTDPNQCIFCQKVMSCRSSLQMHIRTHTGERPFRCKICGRAFATKGNLKAHMSIHKIKPPMRSQFKCPVCHQKFSNGIILQQHIRIHTMDDGSGGQGAPAANPGEAERLGIEDQNSNKSLGTSDTLDFS------------TTISDHSGQRSESSQGGDFDEFMTMDSTDDSR-DNSSAATATPHPLERERDREKERERRIPNDCS--DERSHSNPDLTGGRSESGEMPAMDLSSPSSNSGRIFATG-LANGAAGGGSGNGGLPMLGMPMPPNLLLMAAAREEMHALGHAHAKFPLLPFGPLGFMGLHPPPNVCNLCFKMLPSLAALESHLQSEHAKEPATGHAQRPQCSDAGSPYGAKLTLNPNLFAKKPPSSSSSSSGEKLPESSNPPFPAENPPATPIKEDPDQEQLMVEEGASAGEGSGTGATSNYPQEAGDAEQSLMKMQLHAHRFPASPLDFQQALMSAGPPTSSLDPPVNNKHFCHVCRRNFSSSSALQIHMRTHTGDKPFQCNVCQKAFTTKGNLKVHMGTHMWTNPTSRRGRRMSLELPMRPGPNSGQGHPGSSAEQEFMQRRPELFFPYLPPFFNGLPPKPGELSPGAFPNIPPPPFANGGKYPYPPGLLGFPGFLAQHPYILERRSSSKSPTPEPAQSPALREEEGSGNIWHPLSRIKVENNQNESMGGFNEQEDHAETDATGGDNDESESRDAEK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39770-1", "uniprot_id": "SALM_DROME", "id": "P39770-1", "name": "Homeotic protein spalt-major", "aln": "MKNHLSNVLCAMRSDFKDNHQETINKMIQFGTVKYGIVKQLKDRARSADKDIGSDQEENGGCSPLTTATTTASPSRSPEPEEEQPEEQSTSEQSIPEQSTPDHQLENDIKSEAKSEIEPVEDNNNRVAMTKPSSEEREPNASGSMPSSPVAEASAEEAATERTPEKEKEKDVEVDVEKPDEAPSSAVPSTEVTLPGG---AGAPVTLEAIQNMQMAIAQFAAKTIANGSNGADNEAAMKQLAFLQQTLFNLQQQQLFQIQLIQQLQSQLALNQAKQEEDTEEDADQEQDQEQETDTYEEEERIADMELRQKAEARMAEAKARQHLINAGVPLRE----------SSGSPAESLKRRREHDHESQPNRRPSLDNTHKADTAQDALAKLKEMENTPLP---FGSDLASSIITNHDDLPEPNS---LDLLQKRAQEVLDSASQGILANSMADDFAFGEKSGEGKGRNEPFFKHRCRYCGKVFGSDSALQIHIRSHTGERPFKCNVCGSRFTTKGNLKVHFQRHAQKFPHVPMNATPIPEHMDKFHPPLLDQMSPTDSSPNHSPAPPPLGSAPASFPPAFPGLQNLYRPPMEILKSLGAAAPHQYFPQELPTDLRKPSPQLDEDEPQVKNEPVEEKDQREEHEQEMAECSEPEPEPLPLEVRIKEERVEEQEQVKQEDHRIEPRRTPSPSSEHRSPHHHRHSHMGYPPVVQPIQPAALMHPQSSPGSQSHLDHLPTPGQLPPREDFFAERFPLNFTTAKMLSPEHHSPVRSPAGGALPPGVPPPPHHHPHHMARSPFFNPIKHEMAALLPRPHSNDNSWENFIEVSNTCETMKLKELMK--NKKISDPNQCVVCDRVLSCKSALQMHYRTHTGERPFKCRICGRAFTTKGNLKTHMAVHKIRPPMRNFHQCPVCHKKYSNALVLQQHIRLHTGEPTDLTPEQIQAAEIRDPPPSMMPGHFMNPFAAAAFHFGALP--GGPGGPPGPNHGAHNGALGSESSQGDMDDNMDCGEDYDDDVSSEHLSNSNLEQEGDRSRSGDDFKSLLFEQKLRIDATGVVNTNPVRPRSSASSHGHSVGSTSAPTSPSVHASSQVIKRSSSPARSEASQG--ALDLTPRAAPTSSSSSRSPLPKEKPVSPPSLPRSPSGSSHA-----SANILTSPLPPTVGIDCLPPGLQHHLQQQHQHLMQQQAAVAAAAAAQHHHHQQMAALHQHQEQLRREAAEAQQKAAAAAAAAAAAAAAQRQTPPQARDQRQEGGPGAGPPPNPLMGARPPFGMFPNLPLFPPATTQNMCNAMN-QIAQSVMPAAPFNPLALSGVRGSTTCGICYKTFPCHSALEIHYRSHTKERPFKCSICDRGFTTKGNLKQHMLTHKIRDMEQETFRNRAVK--------------------------------YMSEWNEDRE-----------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :: : . . . :. : . . .. : .: : : : . * .. * :* :* ::*:***: : . . . : : . :: :*:*:: *:***:::: *: : . . . :. . . : . . :. : . . * .. . . . * . * : . * . . . . : :***:*::*.*:*** ******:********: **:**.:*:*:******:*** : :* : : . *: .. . . . :. . . : * * :* : * .: .: : . . : . . : * . .: .::: : .** **::*:. :.* :***:*:.*.:::**:*:*:** *********:*::*****:******:* ::*: **:* ..**:*::*::*.::******:* . . . : . . . . . *. :. : . . : :: . . :.: : : . :.: : : . : . : . :* * .:: . :. .:: . . : .:: : :: : : : . . :: .. . . . : :: .. . . * * :.*.. ***:** *:** ::** *.:* :.******** ** ** . . *. ::. : : :. ", "identical_positions": 150, "similar_positions": 263, "identity": "9.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020228-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NSC2-1", "uniprot_id": "SALL1_HUMAN", "id": "Q9NSC2-1", "name": "Sal-like protein 1", "aln": "----MSRRKQAKPQHFQSDPEVASLPRRDGDTEKGQPSRPTKSKDAHVCGRCCAEFFELSDLLLHKKNCTKNQLVLIVN-ENP--ASPPETFSPSPPPDNPDEQMNDTVNKTDQVDCSDLSEHNGLDREESMEVEAPVANKSGSGTSSGSHSSTAPSSSSSSSSSSGGGGSSSTGTSAITTSLPQLGDLTTLGNFSVINSNVIIENLQSTKVAVAQFSQEA----RCGGASGGKLAVPALMEQ-LLALQQQQIHQLQLIEQIRHQILLLASQNADLPTS-SSPSQGTLRTSANPLSTLSSHLSQQLAAAAGLAQSLASQSASISGVKQLPPIQLPQSSSGNTIIPSNSGSSPNMNILAAAVTTPSSEKVASSAGASHVSNPAVSSSSSPAFAISSLLSPASNPLLPQQASANSVFPSPLPNIGTTAEDLNSLSALAQQRKSKPPNVTAFEAKSTSDEAFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEHLDNIP----------------TSTGIPYG---MSIPPEKPVTSWLDTKPVLPTLTTSVGLPLPPTLPSLIPFIKT---------------------------------EEPAPIPISHSATSPPGSVKSDSGGPESATRNLGGLPEEAEGSTLPPSGGKSEESGMVTNSVPTASSSVLSSPAADCGPAGSATTFTNPLLPLMSEQFKAKFPFG------------------------------------------------------------------GLLDSAQASETSKLQQLVENIDKKATDPNECIICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPVPDSYSESMESDTGSFDEKNFDDLDNFSDENMEDCPEGSIPDTPKSADASQDSLSSSPLPLEMSSIAALENQMKMINAGLAEQLQASLKSVENGSIEGDVLTNDSSSVGGDMESQSAGSPAISESTSSMQALSPSNSTQEFHKSPSIEEKPQRAVPSEFANGLSPTPVNGGALDLTSSHAEKIIKEDSLGILFPFRDRGKFKNTACDICGKTFACQSALDIHYRSHTKERPFICTVCNRGFSTKGNLKQHMLTHQMRDLPSQLFEPSSNLGPNQNSAVIP-ANSLSSLIKTEVNGFVHVSPQDSKDTPTSHVPSGPLSSSATSPVLLPALPRRTPKQHYCNTCGKTFSSSSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHMGTHMWNSTPARRGRRLSVDGPMTFLGGNPVKFPEMFQKDLAARSGSGDPSSFWNQYAAALSNGLAMKANEISVIQNGGIPPIPGSLGSGNSSPVSGLTGNLERLQNSEPNAPLAGLEKMASSENGTNFRFTRFVEDSKEIVTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9ER74-1", "uniprot_id": "SALL1_MOUSE", "id": "Q9ER74-1", "name": "Sal-like protein 1", "aln": "----MSRRKQAKPQHFQSDPEVASLPRRDGDTEKGQPSRPTKSKDAHVCGRCCAEFFELSDLLLHKKSCTKNQLVLIVN-ESP--ASPAKTFPPGPSLNDPDDQMKDAANKADQEDCSDLSEPKGLDREESMEVEVPVATTTTTTTGGSGGSGGSTLSGVTNITTPSCHSGCSSGTSAITTSLPQLGDLTTLGNFSVINSNVIIENLQSTKVAVAQFSQEA----RCGGASGGKLLISTLMEQ-LLALQQQQIHQLQLIEQIRHQILLLASQSADLPAAPSIPSQGTLRTSANPLTTLSSHLSQQLAVAAGLAQSLASQSANISGVKQLPHVQLPQSSSGTSIVPPSGGTSPNMSIVTAAVPTPSSEKVASNAGASHVSSPAVSASSSPAFAISSLLSPESNPLLPQPTPANAVFPTPLPNIATTAEDLNSLSALAQQRKSKPPNVTAFEAKSTSDEAFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEHLDNVP----------------TSTGIPYG---MSIPSEKPVTSWLDTKPVLPTLTTSVGLPLPPTLPSLTPFIKT---------------------------------EEPAPIPISHSAASPQGSVKSDSGAPDLATRNPSGVPEEVEGSAVPPFGGKGEESNMASSAVPTAGNSTLNSPVADGGPGG--TTFTNPLLPLMSEQFKAKFPFG------------------------------------------------------------------GLLDSAQASETSKLQQLVENIDKKATDPNECIICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPVPDNYPESMESDTGSFDEKNFDDLDNFSDENMEECPEGSIPDTPKSADASQDSLSSSPLPLEMSSIAALENQMKMINAGLAEQLQASLKSVENGSMEGDVLTNDSSSVGGDMESQSAGSPAISESTSSMQALSPSNSTQEFHKSPGMEEKPQRVGPGEFANGLSPTPVNGGALDLTSSHAEKIIKEDSLGILFPFRDRGKFKNTACDICGKTFACQSALDIHYRSHTKERPFICTVCNRGFSTKGNLKQHMLTHQMRDLPSQLFEPSSNLGPNQNSAVIP-ANSLSSLIKTEVNGFVHVSPQDSKDAPTSHVPQGPLSSSATSPVLLPALPRRTPKQHYCNTCGKTFSSSSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHMGTHMWNSTPARRGRRLSVDGPMTFLGGNPVKFPEMFQKDLAARSGSGDPSSFWNQYTAALSNGLAMKANEISVIQNGGIPPIPGSLGSG-SSPISGLTGNVEKLGNSEPSAPLAGLEKMASSENGTNFRFTRFVEDSKEIVTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B6U0-1", "uniprot_id": "A0ACD6B6U0_DANRE", "id": "A0ACD6B6U0-1", "name": "Sal-like protein 1", "aln": "----MSRRKQAKPQYVLLDHTMEIEP--------------SPTCDVHICEQCCAEFSSITELYQHQKDCSKDQLVLIVS-ENESLDSPPSALTVNSPFFNTEEHSDGVTNNDSTEDLGDSS-----NEGTLLEVEEPLDVLEIHGIDKKSHECSN-----------------DGLSSAYSASLPQDIALLELCKLSAFNSNVFIENLENTKVAVAQFSQETPLKTSCINASNAKKVDLGLIEQ-LLALQQQQMQQLKLIEEIRAQIMLLATQNSKTPLTTNSNGLSQSRS----LIKLSSELSEQLTAAAGLAENLAANAKQSTHVVPQNQDGLRGEKEDSKVT---SKIRDNTFPMKLDIDQSGNQSLHDSKVSNKVDGGANLKTPSPSPASDGIVN---KLELPHKPNSFNISANSLPSIGAIVEDLNALTALAQHRKAKPVNVSLCEHKRPSEDCIFKHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNICGNRFSTRGNLKVHFQRHKEKYPNVLMNPYPVPEHLDNVL----------------TSTGIPYG---MSVPQEKPPLSWLDSKPLVG---NSIGFMLSSSLPGLPVIIKK---------------------------------EEEG-----VSITKPHSPVVS------ELTKRINGHQEEFVCSPPIISNEKFQEVNQR-LSVSTLLRSSREGSREDIAVNT--SVNTGLITKLKSEQLEAKFLLG------------------------------------------------------------------SLPNPLGASETSKLEQLVENIDKKYTDPNECGICHRVLSCQSALKMHFRTHTGERPFKCRVCGRAFTTKGNLKTHYSIHRSMPPLRIQNSCPICQEKFTNAMVLQQHIHMHMGGHIPNVPMHDSSEELMDQDL-------VESMDTFPNEDTDTMQGASDLKNPDSLTESECSSPAS------SVFARSESQIKVANVEKLEN--TSKLVIQDGSVEGDCLTQGLASQN--IEHESLRRRIPSESTASWSPSSPKGYTTIDPKS--AESNNSNLTVSRLLDGAS-----------------GEVQKDTLTMVFPYINQGSLKSNVCDICNKMFACQSALDIHYRSHTKERPFICTACNRGFSTKGNLKQHMLTHQMRELPSQLFEPANKILVLPPNHLLPSVETNIPPKRIEHNGFIKK---DLKDSPSCIFS----SSASTMPVLPTPTLRRTAKQHFCQTCGKTFSSSSALQIHERTHTGEKPFACNICGRAFTTKGNLKVHMGTHMWSSSPARRGRKLSVDG--PYITSNSERFQDGHPKDVVAKVRNGDSVGLWSQH----HNGSGLRTNEIPVIQNGAIPHLS----------IS--AGHLENLEKLQLNRALPWLERLS--ENGAAFHFRQLVEDHKTTLMD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P39770-1", "uniprot_id": "SALM_DROME", "id": "P39770-1", "name": "Homeotic protein spalt-major", "aln": "MKNHLSNVLCAMRSDFKDNHQETINKMIQFGTVKYGIVKQLKDRARSADKDIGSDQEENGGCSPLTTATTTASPSRSPEPEEEQPEEQSTSEQSIPEQSTPDHQLENDIKSEAKSEIEPVEDNNNRVAMTKPSSEEREPNASGSMPSSPVAEASAEEAATERTPEKEKEKDVEVDVEKPDEAPSSAVPSTEVTLPGGAGAPVTLEAIQNMQMAIAQFAAKTIANGSNGADNEAAMKQLAFLQQTLFNLQQQQLFQIQLIQQLQSQLALNQAKQEEDTEEDADQEQDQEQE-------TDTYEEEERIADMELRQKAEARMAEAKARQHLINAGVPLRESSGSPAESLKRRREHDHESQPNR-RPSLDNTHKADTAQDALAKLKEMENTPLPFGSDLAS---SIITNHDDLPEPNSLDLLQKRAQEVLDSASQGILANSMADDFAFGEKSGEGKGRNEPFFKHRCRYCGKVFGSDSALQIHIRSHTGERPFKCNVCGSRFTTKGNLKVHFQRHAQKFPHVPMNATPIPEHMDKFHPPLLDQMSPTDSSPNHSPAPPPLGSAPASFPPAFPGLQNLYRPPMEILKSLGAAAPHQYFPQELPTDLRKPSPQLDEDEPQVKNEPVEEKDQREEHEQEMAECSEPEPEPLPLEVRIKEERVEEQEQVKQEDHRIEPRRTPSPSSEHRSPHHHRHSHMGYPPVVQPIQPAALMHPQSSPGSQSHLDHLPTPGQLPPREDFFAERFPLNFTTAKMLSPEHHSPVRSPAGGALPPGVPPPPHHHPHHMARSPFFNPIKHEMAALLPRPHSNDNSWENFIEVSNTCETMKLKELMK--NKKISDPNQCVVCDRVLSCKSALQMHYRTHTGERPFKCRICGRAFTTKGNLKTHMAVHKIRPPMRNFHQCPVCHKKYSNALVLQQHIRLHTGEPTDLTPEQIQAAEIRDPPPSMMPGHFMNPFAAAAFHFGALPGGPGGPPGPNHGAHNGALGSESSQGDMDDNMDCGEDYDDDVSSEHLSN--SNLEQEGDRSRSGDDFKSLLFEQKLRIDATGVVNTNPVRPRSSASSHGHSVGSTSAPTSPSVHASSQVIKRSSSPARSEAS--------------QGALDLTPRAAPTSSSSSRSPLPKEKPVSPPSLPRSPSGSSHASANILTSPLPPTVGIDCLPPG--LQHHLQQQHQHLMQQQAAVAAAAAAQHHHHQQMAALHQHQEQLRREAA-----------EAQQKAAAAAAAAAAAAAAQRQTPPQARDQRQEGGPGAGPPPNP----LMGARPPFGMFPNLPLFPPATTQNMCNAMNQIAQSVMPAAPFNPLALSGVRG-STTCGICYKTFPCHSALEIHYRSHTKE------------------RPFKCSICDRG--------------------FTTKGNLKQHMLTHKIRDMEQETFRNRAVKY-MSEWNEDRE-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. * . . : :: . . :. . . *. . . : . .:.: .. :. : . . * . . . . : .. : . .: * :* ::. ::*:***: :: . . :::* *: *****: *::**:::: *: * ::. . . . : .: .:: . * :. :. . . : ... . : .. :. . :... :* ..: . . : . * . . . * : **: . :: :***:**:*.************:********:***:**.**:*:********** :*:*:: **. *:***:*:. :.: * * *.* * . * *: . . * ::. .* . * . : . . : .. . . : . * .: : :* :. .: : :.** **::*:: :** :***:* :*.*****:***:**:***********::************** ::*: **:* :.**:*::*::**:******::* * .* . * : .: : . . . *. . . * . : *. . . .: :. : * .** :.. . :: . .. :* .. . . : .* . . . . . :. . . . . . :. :. ..: . * :: *: *. :.. *::*: :: : : .* .: :. . : * :: . ::::: . .. * :*. .* . .. : *. * * : : . * ::. : ::* . .* * . * :: : . : :. : .: :.* .* : . : :*: : :... : : . ** : ", "identical_positions": 191, "similar_positions": 334, "identity": "13.12%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020228-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A024-1", "uniprot_id": "D4A024_RAT", "id": "D4A024-1", "name": "Sal-like protein 3", "aln": "---------MSRRKQAKPQHLKSDEELPPQDGASEHGVPGDGAEDADSSSESRSGSEETSVCEKCCAEFFKWA---------DFLQHKKTCTKNPLVLIVHDD--EPAPPSEDFPEPSPAS---SPSDRTESEVAEEVAPPEGSE--------VKAVAKEVEPMDVEASADQ--------GPPGPSVPPPPPALPPQPEPAAFSMPSTNVTLETLLSTKVAVAQFSQGARAGGTTGAGGSVGAVAIPMILEQLVALQQQQIHQLQLIEQIRSQVALMSRQPGPP----------------LKPSASAPGAAS-VQLPGLTPHASLQLSAG-PATASAGSGSTLSAAFDGPQHLSQPQPASGTSTPCSTSAGPTDSGAHPACSTGPAPGAVAAASS-TVGNTVQ---------------PQNASTPPALGPGPLLSSASSLPSPLLPQTSSSSVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDN---------VPTCSGIPYGMSLPPE----------------------------------------------KPVTTWLDSKPVLPTVPTSVGLQLPPTVPGTHN-YTDSPSITPISR---------------------SPQRPSPASSECTSLSPGLNNTESGITVRPESPQPLLGG--PPLTKAEPVSLPCTS-TRTGDAPVVGGQVSGLPTPAATTVTDSACTSLGS----------------------PGLPAVSDQFKAQFP--------FGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGLQEAMDAELPFDEKNAETLSSFDDDVD---ENSMEEDSELKDTASDSSKPLLSYSGSCPPSPP--SVISSIAALENQMKMIDSVMNCQQLASLKSVENGSGES----DRLSNDSSSAVGDLESRSAGSPALSESS-SSQALSPAHSNGESFRSKSPGLSHQEDPQEIP-------LKTERLDSPPPGPGNGGALDLTAGHPGRPLIKEEAPFSLLFLSRERGKCASTVCGVCGKPFACKSALEIHYRSHTKERPFVCTVCRRGCSTMGNLKQHLLTHKLKELPSQVFDPNFTLGPSHSTPSLASSPAPTMIKMEVNGHSKAIALGEGPALPAGVQVPTG-PQTVMSPGLAPMLAPPP-RRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKG---NLK------------------------------------------------VHMGTHMWNNAPARRGRRLSVENPMALLGGDALKFSEMFQKDLAARAMNVDPSFWNQYAAAITNGLAMKNNEISVIQNGGIPQLPVSLGGGAIPPLGAMAGGVDKTRTGSSPPIVSLDKASPETGASRPFTRFIEDNKEIGIN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62255-1", "uniprot_id": "SALL3_MOUSE", "id": "Q62255-1", "name": "Sal-like protein 3", "aln": "---------MSRRKQAKPQHLKSDEELPPQDGASEHGVPGDGAEDADSGSESRSGSEETSVCEKCCAEFFKWA---------DFLQHKKTCTKNPLVLIVHDD--EPAPPSEDFPEPSPAS---SPSDRTESEVAEEVAPTEGSE--------VKAATKEAEPMDVEVSTDK--------GPPGPSVPPPPPALPPQPEPAAFSMPSTNVTLETLLSTKVAVAQFSQGARAGGTTGAGGSVGAVAIPMILEQLVALQQQQIHQLQLIEQIRSQVALMSRQPGPP----------------LKPSASAPGTAS-VQLQGLTPHAALQLSAG-PATASAGSGSTLPAAFDGPQHLSQP--ASGTSTPCSTSAAPPDSGAHPACSTGPAPGAVAAASS-TVGNAVQ---------------PQNASTPPALGPGPLLSSASNLPNPLLPQTSSSSVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDN---------VPTCSGIPYGMSLPPE----------------------------------------------KPVTTWLDSKPVLPTVPTSVGLQLPPTVPGTHN-YTDSPSITPVSR---------------------SPQRPSPASSECTSLSPGLNNTESGITVRPESPQPLLGG--PSLTKAEPVSLPCTS-TRTGDAPVVGGQVSGLPTSAATAVTDSACTSLGS----------------------PGLPAVSDQFKAQFP--------FGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGLQEAMDADLPFDEKNAETLSSFDDDID---ENSMEEDSELKDTASDSSKPLLSYSGSCPPSPP--SVISSIAALENQMKMIDSVMNCQQLANLKSVENGSGES----DRLSNDSSSAVGDLESRSAGSPALSESS-SSQALSPAHSNGESFRSKSPGLGHQEDPQEIP-------LKTERLDSPPPGPGNGGALDLTAGHPGRPLIKEEAPFSLLFLSRERGKCASTVCGVCGKPFACKSALEIHYRSHTKERRFVCTVCRRGCSTMGNLKQHLLTHKLKELPSQVFDPNFTLGPSHSTPSLASSPAPTMIKMEVNGHSKAIALGEGPALPAGVQVPTG-PQTVMSPGLAPMLAPPP-RRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKG---NLK------------------------------------------------VHMGTHMWNNAPARRGRRLSVENPMALLGGDALKFSEMFQKDLAARAMNVDPSFWNQYAAAITNGLAMKNNEISVIQNGGIPQLPVSLGGGAIPPLGAMASGVDKARTGSSPPIVSLDKASSETGASRPFARFIEDNKEIGIN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXA9-1", "uniprot_id": "SALL3_HUMAN", "id": "Q9BXA9-1", "name": "Sal-like protein 3", "aln": "---------MSRRKQAKPQHLKSDEELLPPDGAPEHAAPGEGAEDADSGPESRSGGEETSVCEKCCAEFFKWA---------DFLEHQRSCTKLPPVLIVHED--APAPPPEDFPEPSPAS---SPSERAESEAAEEAG-AEGAEG------EARPVEKEAEPMDAEPAGDT--------RAPRP---PPAAPAPPTP---AYGAPSTNVTLEALLSTKVAVAQFSQGARAAGGSGAGGGVAAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRP----------------SLSPAAAPSAPG-PAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRP--ESGASTPG----GPAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQ---------------PQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDN---------VPTCSGIPYGMSLPPE----------------------------------------------KPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHG-YADSPSATPASR---------------------SPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGG--PPLTKAEPVSLPCTN-ARAGDAP-VGAQAS-----AAPTSVDGAPTSLGS----------------------PGLPAVSEQFKAQFP--------FGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQDAMDSELAYDDKNAETLSSYDDDMD---ENSMEDDAELKDAATDPAKPLLSYAGSCPPSPP--SVISSIAALENQMKMIDSVMSCQQLTGLKSVENGSGES----DRLSNDSSSAVGDLESRSAGSPALSESS-SSQALSPAPSNGESFRSKSPGLGAPEEPQEIP-------LKTERPDSPAAAPGSG-------GAPGRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAG-PQTVMGPGLAPMLAPPP-RRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKG---NLK------------------------------------------------VHMGTHMWNNAPARRGRRLSVENPMALLGGDALKFSEMFQKDLAARAMNVDPSFWNQYAAAITNGLAMKNNEISVIQNGGIPQLPVSLGGSALPPLGSMASGMDKARTGSSPPIVSLDKASSETAASRPFTRFIEDNKEIGIN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TJ01-1", "uniprot_id": "A0AB32TJ01_DANRE", "id": "A0AB32TJ01-1", "name": "Sal-like protein 1", "aln": "---------MSRRKQAKPQQLRSDEDPTLLELLPEH-VSGEGVDDSDSGNESRSGSEETHVCEKCCAEFFKWS---------DFCEHLKTCTKNPLVLIISDNEVTSDPAQDYLPEPSPVPSCVSDPANSEDAVEVSHMPTEGDEGAEMMLESGAVLEKEDEPMEVELSPEKPIDPDDPVTLAEPDISLPPLEDHKQSSGAGYSIPSTNVTLETLHGTRVAVAQFSQGARGALAS----EVSTMAIPMILDQLMALQQQQLRQLKLIEQIRSQVALINNQAPTQTAVSHKVDHSINAALQVPSSSSIPAMPGQLHLRGFITPPINQLHMKGPNSLNVQASVAVSSALDVACTSGSP--AGGQLASSGMKSNIAINSLYPTTSNGVSPQMPPCSVSISSSSCTSSSTGTGGEINCGISLPRNTPSPLTLTHGRLLTSPSSLP--LVPHSSSNSVIFPNPLASIAATTNALDPLSALMKHRKGKPPNVSVFDTKPSSEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDN---------VPTSSGIPYGMSLPPE----------------------------------------------KPVTTWLDSKPILPTIPTSVALQLPPTIPSIIGSYGDSTSFSPLNR---------------------SPQRPSPPSSECTSLSPNHLITETSIAQISSSPQPNLASNTPPVLKPEALHLPANSTTRPGETSISTTSISQVISTTIVTTTCSTRTQLTDP------------VNSSSAVSHPSLQISLNQFKPKFP--------FGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRIHTGERPFKCKICGRAFTTKGNLKTHFGVHRSKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPDTFQDT-DADLSFDEKSLDAMSNYDDELIDEMDQALEDETGLKDENMDLQKQLHLYSEMSPSTSPPTSLISSIGAFENEMKLSDPAVNITHSFSVKPTENGSGVDGVNGDMLKNDLSSTLVDLENHSVGSPAQSESSGSMLALSPTYSQSESHRSKSPQANSSSKDEALTSTSAHAMVKSEQLDIHSPGSENTGALDLTATQPTRSFVKDENPFSLLFLGRDRG--------------------------------------------------------------------------LSTPSNISSES-STVKFEN-GHSKPPALCEGPHLPVGPQVPTATAQTTISSNITPMLAPPPPRRTPKQHNCHSCGKNFSSASALQIHERTHTGEKPFGCSICGRAFTTKG---NLKEEGRWFEPRLGQLVFLCGVCMLSLHSRGFPPGAPVSPIVQRHATQVNWVHMGTHMWNNAPARRGRRLSVENPMALLGGDAIKFSEMFQKDLAARAINVDPGFWNQYAVAITSGLAMKNNEISVIQNGGIPSIPISLSGGGIPAVGGMSGGIERSRTGSSPPVTGLEKTNLEMGTGHPFSRFREEEKEVGIN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P39770-1", "uniprot_id": "SALM_DROME", "id": "P39770-1", "name": "Homeotic protein spalt-major", "aln": "MKNHLSNVLCAMRSDFKDNHQETINKMIQFGTVKYGIVKQLKDRARSADKDIGSDQEENGGCSPLTTATTTASPSRSPEPEEEQPEEQSTSEQSIPEQSTPDHQLENDIKSEAKSEIEPVEDNNNRVAMTKPSSEEREPNASGSMP------SSPVAEASAEEAATERTPEKEKEKDVEVDVEKPD--EAPSSAVPSTEVTLPGGAGAPVTLEAIQNMQMAIAQFAAKTIANGSNGADNEAAMKQLAFLQQTLFNLQQQQLFQIQLIQQLQSQLALNQAKQEED----------------TEEDADQEQDQEQETDTYEEEERIADMELRQKAEARMAEAKARQHLINAGVPLRES---SGSPAESLKRRREHDHESQPNRRPSLDNTHKADTAQDALAKLKE-------------------MENTPLPFGSDLASSIITNHDDLPEPNSLDLLQKRAQEVLDSASQGILANSMADDFAFGEKS-----GEGKGRNEPFFKHRCRYCGKVFGSDSALQIHIRSHTGERPFKCNVCGSRFTTKGNLKVHFQRHAQKFPHVPMNATPIPEHMDKFHPPLLDQMSPTDSSPNHSPAPPPLGSAPASFPPAFPGLQNLYRPPMEILKSLGAAAPHQYFPQELPTDLRKPSPQLDEDEPQVKNEPVEEKDQREEHEQEMAECSEPEPEPLPLEVRIKEERVEEQEQVKQEDHRIEPRRTPSPSSEHRSPHHHRHSHMGYPPVVQPIQPAALMHPQSSPGSQSHLDHLPTPGQLPPREDFFAERFPLNFTTAKMLSPEHHSPVRSPAGGALPPGVPPPPHHHPHHMARSPFFNPIKHEMAALLPRPHSNDNSWENFIEVSNTCETMKLKELMK--NKKISDPNQCVVCDRVLSCKSALQMHYRTHTGERPFKCRICGRAFTTKGNLKTHMAVHKIRPPMRNFHQCPVCHKKYSNALVLQQHIRLHTG--EPTDLTPEQIQAAEIRDPPPSMMPGHFMNPFAAAAF--------HFGALPGGPGGPPGPNHGAHNGALGSES------SQGDMDDNMDCGEDYDDDVSSEHLSNSNLEQEGDR---SRSGDDFKSLLFEQKLRIDATGVVNTNPVRPRSSASSHGHSVGSTSAPTSPSVHASSQVIKRS-----SSPARSEASQGALDLTPRAAPTSSSSSRSPLPKEKPVSPPSLPRSPS-----------------------------------------------------------------------GSSHASANILTSPLPPTVGIDCLPPGLQHHLQQQHQHLMQQQAAVAAAAAAQHHHHQQMAALHQHQEQLRREAAEAQQKAAAAAAAAAAAAAAQRQTPPQARDQRQEGGPGAGPPP------------------------------------------------------NPLMGARPPFGMFPNLPLFPPATTQN-MCNAMNQIAQSVMPAAPFN--PLALSGVRGSTTCGICYKTFPCHSALEIHYRSHTKERPFKCSICDRGFTTKGNLKQHMLTHKIRDMEQETFRNRAVKYMSEWNEDRE-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.: * :: .: :. . .:. : *. **. *. : . : : :. :. : :. : .* .*. . :: ..* . * .* : : * .. . . ..: ****:: . ::*:***: : . . .. :.:: : *. *****: *::**:*::**:** . : : . : :: . .* : . . . : . . .* * * :. :*...: .:: .. : ::::.: . * .. *: . . ::*****:**:*.************:************:**.**:************ :*:**: **. *:**::*: ** *. :. : ** ** . :.:* : . *.. * ... * . . : ***.*.. :. . .* . : .. :.. ** . . : : : . * : .:: . :* : .::: :*.** **::*:: :**::******:*.*****:***:**** *********:***************:.**: :**:* *.**:*:**::**:*******:* * *. *: :* : : . . . :. : . * . . . : . * . ::::*. : . :. : . . . :* .* : : : : .: . . .. : :.: .:. . * .. . . : : .. : : . . *. : .* *.* * *. . ::.. :* . : :: . * : *.... . :. * * :. ::. ..: * ::*:* :: * . .. . * .. * ..* .*.: * : . . :.:: *. :.* .:* * . : * *:. *. : . . . .:: : : : : .::: . . : : ::.: *:.: ", "identical_positions": 228, "similar_positions": 361, "identity": "14.48%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020312-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A0M3-1", "uniprot_id": "D4A0M3_RAT", "id": "D4A0M3-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENELPVPHTSSRASITTNTSGTNSSSGCSSSSGGG---SGRPTAPQISVYSG-IPDRQTVQVIQQALHRQPS-TAAQYLQQMYAAQ----QQHLMLQTAALQQQHLSSAQLQSLAAVQQAS---------LVANRQGSTSGSSVSSQAPAQSSSLNLAASPAAAQLINRAQSVNSATASGLAQQAVLLGNTSSPALTASQAQMYLRAQM------------------------------------LIFTPTATVATVQPELGTGSPARPPTPAQVQNLTLRTQQTPAAAAAAAASGPAPTQPVLPSLALKPTPSSSQPLPPTPQGRTVVQGSPVG--AKPSVTDNVTEPLKT-DGNS----NMEARPGPDRATVPTVATHQLTAPAYTQLQP---HQLLPQPSSKHPQPQFVAQQQPQP----------PRPTPQVQSQPQLAAVSPSLALQPSPEGHAMPLGPV---------------------TQALPLQCSTAHVHKPGSSQQCHLPTPDSGSQNGHPEG--VSHAPQRRFQHTSAVILQLQPASPV----------------------------------------PQQCAPDDWKEVVPAEKSVPVTRPGLSPHQQAIITAIPGG---------------------------LPGPKSPNIQQCPAHETGQGIVHALTDLSSP-GMTSGNGNS---------ASSITGTAPQNGENKPP-------------------------------------------------------------------------------------QAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGTPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYN-----VGCTKRVGLFHSDRSKLQKAGTTTHNRRRASKASLPTLTKDTKKQPSGTVPLSVTAALQLAH----SQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELSDMHMRDLVGMG-HHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QWH1-1", "uniprot_id": "PHC2_MOUSE", "id": "Q9QWH1-1", "name": "Polyhomeotic-like protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENELPVPHTSNRASVTTNTSGTNSSSGCISSSGGGGGSGGRPTAPQISVYSG-IPDRQTVQVIQQALHRQPS-TAAQYLQQMYAAQ----QQHLMLQTAALQQQHLSSAQLQSLAAVQQAS---------LVANRQGSTPGSSVSSQAPAQSSSLNLAASPAAAQLINRAQSVNSAAASGLAQQAVLLGNTSSPALTASQAQMYLRAQM------------------------------------LIFTPTATVATVQPELCTGSPARPPTPAQVQNLTLRTQQTP----AAAASGPPPTQPVLPSLALKPTPSSSQPLPAPPQGRTMAQGSPAG--AKPSGTDNAPETLKAGDGNC----NMEGRPGPGRA-VPAVATHPLIAPAYAHLQS---HQLLPQPPAKHPQPQFVAQQQPQP----------PRPAPQVQSQPQLASVSPSLALQSSPEDHALPLGSV---------------------TQALPLQCSTTHVHKPGNSQQCHLPTLDTGSQNGHPEG--GSHPPQRRFQHTSAVILQVQPASPVT---------------------------------------PQQCAPDDWKEVVPAEKSVPVARPGPSPHQQAIIPAIPGG---------------------------LPGPKSPNIQQCPAHETGQGIVHALTDLSSP-GMTSGNGNS---------ASSIAGTAPQNGENKPP-------------------------------------------------------------------------------------QAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKPPQQDHTTTTDSEMEEPYLQESKEEGTPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYN-----VGCTKRVGLFHSDRSKLQKAGTTTHNRRRASKASLPTLTKDTKKQPSGTVPLSVTAALQLAH----SQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLDLPDMHMRDLVGVG-HHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IXK0-1", "uniprot_id": "PHC2_HUMAN", "id": "Q8IXK0-1", "name": "Polyhomeotic-like protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENELPVPHTSSSACATSSTSGASSSSGCNNSSSGG---SGRPTGPQISVYSG-IPDRQTVQVIQQALHRQPS-TAAQYLQQMYAAQ----QQHLMLQTAALQQQHLSSAQLQSLAAVQQAS---------LVSNRQGSTSGSNVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPALTASQAQMYLRAQM------------------------------------LIFTPTATVATVQPELGTGSPARPPTPAQVQNLTLRTQQTP----AAAASGPTPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPAG--AKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRT-VPAVAAHPLIAPAYAQLQP---HQLLPQPSSKHLQPQFVIQQQPQPQQQQPP-PQQSRPVLQAEPHPQLASVSPSVALQPSSEAHAMPLGPV---------------------TPALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEG--VPHTPQRRFQHTSAVILQLQPASPP-----------------------------------------QQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGG---------------------------LPVPTSPNIQPSPAHETGQGIVHALTDLSSP-GMTSGNGNS---------ASSIAGTAPQNGENKPP-------------------------------------------------------------------------------------QAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGAPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYN-----VGCTKRVGLFHSDRSKLQKAGAATHNRRRASKASLPPLTKDTKKQPTGTVPLSVTAALQLTH----SQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMHMRDLVGMG-HHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8QHL5-1", "uniprot_id": "PHC2_DANRE", "id": "Q8QHL5-1", "name": "Polyhomeotic-like protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKEQEQGSVASSASVTIPSTTSVSTSTSAGTLSNS--SSRQQTVPQISVYGG-ITDRQTVQVIQQALNRQPSTVAAQYLQQMYAAQ----QQHLMLQTAALQQQHLS------LAAVQQAS---------IVAGRQSCSQHGSTSQQTVASQTTINLATSPAARHLISRAQSG-SSVPVCIGQQAVLLGNSSTPTLTASQAQMYLRAQMAQQTNLVQVA--------------RSLGRAVPLSSQLIFTPTASVTAIQPEAPAPSINTPPTSGQVQNLALRSQQGA--------LTSTLSQSQLQSLSVKQSVASVTGQSVARLKGLGAEPSPQGTAAKASPAETSSETTAKNDKTS----DLTTSVCPSVT---SVAGHPFISTAYTQIQT---HQLLQQH-----KQQFVIQQQPQI-------------LQRGQAQLLEAAAIHPHTVQAVAIQSALPAQPQ---------------------QCPIPLLPKVPVTCQQATIFHSTTVSQQALAQNGQAHI--LTHTKAPPLQLT-AVKCQIHPVQIQ-----------------------------------------QGVASQN----VP-DKDTPVL---LEPQLLSIPIQEPTR---------------------------TELRQSD--KESQVKENTQGSVNVKAGVGSPPAMTSGSGNN---------APTVTGSAPQNGESKPPP------------------------------------------------------------------------------------QAVVKPQILTHVIEGFVIQEGAEPFPVERPSLLIENLKQKQHHAYS----DLQKHN--ADSEMEDLSLQELNNQPEPVR-TCEFCGNVDFAFNFKRSKRFCSTVCAKRYN-----VGCTKRMGLFPG------KSSPEDTKKPKASDESPKNCSTETRKR-NPSIQTTTGASLLSPHPSHPSHGESSQCSDMSSYEEPISPLSNSSFG-----APIEHEESFDHSRELTPLLTQHFLASDPTKWNVEDVYEFICSLPGCHEIAEEFRSQEIDGQALMLLKEDHLMSTMNIKLGPALKIFARISMLKDS------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W523-1", "uniprot_id": "Q9W523_DROME", "id": "Q9W523-1", "name": "", "aln": "MPHGFGAAPSVSVSGDTESESATTIRTPPPS--------PEATTSVKVNSTTRVDP--------------------------------QRPLRCLETLAQKAGISFDEDFAKSPSQSP---SSKAARGS---------------VGTPSIRRRHPLLPLSSRSPSAPDS---------KTTGRKLEKSQSPAQQVAAATNVPLQISPEQLQQLYANNPYAIQVKQEFPTHTTSGSGTELKHATNIMEVQQQLQLQQQLSEANGGGAASAGAGGAASPANSQQSQQQQHSTAISTMSPMQLAAATGGVGGDWTQGRTVQLMQPSTSFLYPQMIVSGNLLHPGGLGQQPIQVITAGKPFQGNGPQMLTTTTQNAKQMIGGQAGFAGGNYATCIPSNHNQSPQTVLISPVNVISHSPQQQQNLLQSMAAAAQQQQLTQQQQQQLNQQQQQLNQQQQQQQLTAALAKVGVDAQGKLAQKVVQKVTTTSSTVQAATGPGSTGSTQTQQVQQVQQQQQQTTQTTQQCVQVSQSTLPVGVGGQSVQTAQLLNAGQAQQMQIPWFWQNAAGLQPFGSNQIILRNQPDGTQGMFIQQQPATQTLQTQQNQIIQCNVTQTPTKARTQLDALAPKQQQQQQQVGTTNQTQQQQLAVATAQLQQQQQQLTAAALQRPGAPVMPHNGTQVRPASSVSTQTAQNQSLLKAKMRNKQQPVRPALATLKTEIGQVAGQNKVVGHLTTVQQQQQATNLQQVVNAAGNKMVVMSTTGTPITLQNGQTLHAATAAGVDKQQQQLQLFQKQHILQQQ-MLQQQIAAIQMQQQQAAVQAQQQQQQQVSQQQQVNAQQQQAVAQ--QQQAVAQAQQQQREQQQQVAQAQAQHQQALANATQQILQVAPNQFITSHQQQQQQQLHNQLIQQQLQQQAQAQVQAQVQAQAQQQQQQREQQQNIIQQIVVQQSTGATSQQQQQQPQQQSGQLQLSSVPFSVSPSMTAEDIAGITSSALQEALSVSGAIFQTTKPITCSSSTLPTSSVVTITSQSSTPLVTSSTVASMQQAQTQGTQIHQHQQLISATIAGGSQQQQQQQQLGLPSLTPTTPSPTTNPILAMTSMMNATVGHLSTAPP--VSVSSTAVTPSSGQLVTLSSASSGGGAGFPATPTKETPSKGPTATLVPIDSPKTPVSGKDTCTTPKSSTPATVSASVEASSSTGEALSNGDASDRSSTPSKGATTPTSKQSNAAVQPPSSTIPNSVSGKEEPKLTTCGSLTSATSTSTTTTITNGIGVARTTASTAVSTASTTTTSSGTFTTSCTSTTTTTTSSISNGSKDLPKAMIKPNVLTHVIDGFIIQEANEPFPVTRQRYADKDVS--------------DEPPKKKATMQEDIKLSGIASAPGSDMVACEQCGKMEHKAKLKR-KRYCSPGCSRQAKNGIGGVGSGETNGLGTGGIVGVDAMALVDRLDEAMAEEKMQTESYQTVSDALPIQAATPEVPPISMP---VLAAMSTSSPLSLPLTLPLPIAIAPTVSLPVVSAGVVAPVLAIPSSNINGSD-----RPPISSWSVEEVSNFIRELPGCQDYVDDFIQQEIDGQALLLLKENHLVNAMGMKLGPALKIVAKVESIKEVPP-GDVKD----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39769-1", "uniprot_id": "PHP_DROME", "id": "P39769-1", "name": "Polyhomeotic-proximal chromatin protein", "aln": "MDR--RALKFMQKRADTESDTTTPVSTTASQGISASAILAGGTLPLKDNSNIREKPLHHNYNHNNNNSSQHSHSHQQQQQQQVGGKQLERPLKCLETLAQKAGITFDEKYDVASPPHPGIAQQQATSGTGPATGSGSVTPTSHRHGTPPTGRRQTHTPSTPNRPSAPSTPNTNCNSIARHTSLTLEKAQNPGQQVAATTTVPLQISPEQLQQFYASNPYAIQVKQEFPTHTTSGSGTELKHATNIMEVQQQLQLQQQLSEANGGGAASAGAGGAASPANSQQSQQQQHSTAISTMSPMQLAAATGGVGGDWTQGRTVQLMQPSTSFLYPQMIVSGNLLHPGGLGQQPIQVITAGKPFQGNGPQMLTTTTQNAKQMIGGQAGFAGGNYATCIPTNHNQSPQTVLFSPMNVIS--PQQQQNLLQSMAAAAQQQQLTQQQQQFNQQQQQQLTQQQQQ--LTAALAKVGVDAQGKLAQKVVQKVTTTSSAVQAATGPGSTGSTQTQQVQQVQQQQQQTTQTTQQCVQVSQSTLPVGVGGQSVQTAQLLNAGQAQQMQIPWFLQNAAGLQPFGPNQIILRNQPDGTQGMFIQQQPATQTLQTQQNQIIQCNVTQTPTKARTQLDALAPKQQQQQQQVGTTNQTQQQQLAVATAQLQQQQQQLTAAALQRPGAPVMPHNGTQVRPASSVSTQTAQNQSLLKAKMRNKQQPVRPALATLKTEIGQVAGQNKVVGHLTTVQQQQQATNLQQVVNAAGNKMVVMSTTGTPITLQNGQTLHAATAAGVDKQQQQLQLFQKQQILQQQQMLQQQIAAIQMQQQQAAVQAQQQQQQQVSQQQQVNAQQQQAVAQ--QQQAVAQAQQQQREQQQQVAQAQAQHQQALANATQQILQVAPNQFITSHQQQQQQQLHNQLIQQQLQQQAQAQVQAQVQAQAQQQQQQREQQQNIIQQIVVQQSGATSQQTSQQQQHHQSGQLQLSSVPFSVSSSTTPAGIA--TSSALQAALSASGAIFQTAKPGTCSSSS-PTSSVVTITNQSSTPLVTSSTVASIQQAQTQSAQVHQHQQLISATIAGGTQQQPQ----GPPSLTPTT-----NPILAMTSMMNATVGHLSTAPPVTVSVTSTAVTSSPGQLVLLSTASSGGGGSIPATPTKETPSKGPTATLVPIGSPKTPVSGKDTCTTPKSSTPATVSASVEASSSTGEALSNGDASDRSSTPSKGATTPTSKQSNAAVQPPSSTTPNSVSGKEEPKLATCGSLTSATSTSTTTTITNGIGVARTTASTAVSTASTTTTSSGTFITSCTSTTTTTTSSISNGSKDLPKAMIKPNVLTHVIDGFIIQEANEPFPVTRQRYADKDVS--------------DEPPKKKATMQEDIKLSGIASAPGSDMVACEQCGKMEHKAKLKR-KRYCSPGCSRQAKNGIGGVGSGETNGLGTGGIVGVDAMALVDRLDEAMAEEKMQTEATPKLSESFPILGASTEVPPMSLP---VQAAISAPSPLAMPLGSPLSVALPTLAPLSVVTSGAAP-----KSSEVNGTD-----RPPISSWSVDDVSNFIRELPGCQDYVDDFIQQEIDGQALLLLKEKHLVNAMGMKLGPALKIVAKVESIKEVPPPGEAKDPGAQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::: :. . : . . : **. : .. *.. * *..**. . . ::** *:* **: ::* . * : **. ** . : . : . * :::: . :*. : .:.:. * . :*::* .: . .. * *:::: ::::.*.: ::* : . . * *:* * :* . * . ::: . : : : . :: : : . . ** : : :. : * :**: * : *. * *.* : : .: * : . .:. : . : . . ..:. . . :* : : *:: . . . * ... .. . * :.. . * . . .*. . : ..*: ..: . : .*. :** :*::**::*****:**:***. ***** * ::. :. : *: *. . . ** **.::. ::** **:** *::: : **. : ** . . :. . : . . : .. *: .. . *:. . . :: . :.*.*::* :** .****:: .::* ********:****.**:.:*.:******** *::. :*: ", "identical_positions": 128, "similar_positions": 234, "identity": "7.82%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020318-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P02692-1", "uniprot_id": "FABPL_RAT", "id": "P02692-1", "name": "Fatty acid-binding protein, liver", "aln": "MNFSGKYQVQSQENFEPFMKAMGLPEDLIQKGKDIKGVSEIVHEGKKVKLTITYGSKVIHNEFTLGEECELETMTGEKVKAVVKMEGDNKMVTTFKGIKSVTEFNGDTITNTMTLGDIVYKRVSKRI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12710-1", "uniprot_id": "FABPL_MOUSE", "id": "P12710-1", "name": "Fatty acid-binding protein, liver", "aln": "MNFSGKYQLQSQENFEPFMKAIGLPEDLIQKGKDIKGVSEIVHEGKKIKLTITYGPKVVRNEFTLGEECELETMTGEKVKAVVKLEGDNKMVTTFKGIKSVTELNGDTITNTMTLGDIVYKRVSKRI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07148-1", "uniprot_id": "FABPL_HUMAN", "id": "P07148-1", "name": "Fatty acid-binding protein, liver", "aln": "MSFSGKYQLQSQENFEAFMKAIGLPEELIQKGKDIKGVSEIVQNGKHFKFTITAGSKVIQNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKSVTELNGDIITNTMTLGDIVFKRISKRI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1AMT3-1", "uniprot_id": "FAB1A_DANRE", "id": "Q1AMT3-1", "name": "Fatty acid binding protein 1-A, liver", "aln": "MAFTGKYQLESHENFEAFMKAVGVPDDEVEKGKDIKSISEIHQDGKDFKVTVTAGTKVILYSFTVGEECELETFTGDRAKTVVQMDG-NKLTAFVKGIESVTELDGDTISNTLSFNGIVYKRISRRIS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *:****::*:****.****:*:*:: ::******.:*** ::**..*.*:* *.**: .**:********:**::.*:**:::* **:.: .*.*:****::** *:**:::..**:**:*:** ", "identical_positions": 70, "similar_positions": 48, "identity": "54.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020320-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1PFE1-1", "uniprot_id": "A0A8M1PFE1_DANRE", "id": "A0A8M1PFE1-1", "name": "", "aln": "MSKPNYTGVYNMISQDNFEEYLAALDVNYALRKVVCILKPSKHIEHDVNTDRMKIKTVTTFKNFDMDFTLGQEFTEDLGPVDGRKCQTTVDWDGD-KLICVQ---RGEKEGRGWTHWLEGNILHLELRAQGVTAKQVFKKVE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P82980-1", "uniprot_id": "RET5_HUMAN", "id": "P82980-1", "name": "Retinol-binding protein 5", "aln": "MP-PNLTGYYRFVSQKNMEDYLQALNISLAVRKIALLLKPDKEIEHQGN--HMTVRTLSTFRNYTVQFDVGVEFEEDLRSVDGRKCQTIVTWEEE-HLVCVQ---KGEVPNRGWRHWLEGEMLYLELTARDAVCEQVFRKVR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62965-1", "uniprot_id": "RABP1_MOUSE", "id": "P62965-1", "name": "Cellular retinoic acid-binding protein 1", "aln": "--MPNFAGTWKMRSSENFDELLKALGVNAMLRKVAVAAASKPHVEIRQDGDQFYIKTSTTVRTTEINFKVGEGFEEET--VDGRKCRSLPTWENENKIHCTQTLLEGDGPKTYWTRELANDELILTFGADDVVCTRIYVRE-", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** :* :.: *..*::: * **.:. :**:. .. .:* : :: ::* :*.:. ::* :* * *: ******:: *: : :: *.* .*: * : * .: * * : * .... ::: : ", "identical_positions": 32, "similar_positions": 53, "identity": "22.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020320-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZGQ0-1", "uniprot_id": "D3ZGQ0_RAT", "id": "D3ZGQ0-1", "name": "Interleukin-17 receptor D", "aln": "MAPWLQLCSFFFTVNACLNGSQLAVAAGGSGRARGADTCGWR-GVGPASRNSGLYN--ITFRYDNCTTYLSPVGKHMIADAQNITISQYACNDQVAVTILWSPGALGIEFLKGFRVILEELRSEGRLCQQLVLKDPKQLNSSFKRTGMESQPFLNMKFETDYFVKIVPFPSIKNESDYHPFFFRTRACDLLLQPDNLACKPFWKPRNLNITQYGSDMQVSFHHAPQNFGFRGFHVHYKLKHEGPFRRRTCRQDQNTETTSCLLQNVSPGDYVIELVDDSNTTRKAAQYVVKPVQSPWAGPIRAVAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESPESSTYAAVLPRDRLRPRPKVFLCYSSKDGQNHMNVVQCFAYFLQEFCGCEVALDLWEDFSHCIEGQREWVIQKIHESQFIIVVCSKGMKYFVDKKSYRHKGGSRGG----------TGQGELFLVAVAAIAEKLRQAKQSSSAALSKFITVYFDYSCEGDVPCTLDLSTKYKLMDNLPELCSHLHSGEQ--EELGQHPGHSSRRNYFRSKAGRSLYVAICNMHQFIDEEPDWFEKQFVPFHPPPVRYQEPVLEKFDSGLVLNDVISKPGPESDFCLKVEASILGATGPADSYSYLENQHAGLDQDTEAQPACDGGPALQPLLHAVKAGSPSDMPRDSGIYDSSVPSSELSLPLMEGLSPDQIETSSLTESVSSSSGLGEEDPPTFPSKLLASG-VSKGEHGFHSYT--DELQAAAPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JZL1-1", "uniprot_id": "I17RD_MOUSE", "id": "Q8JZL1-1", "name": "Interleukin-17 receptor D", "aln": "MAPWLQLCSFFFTVNACLNGSQLAVAAGGSGRARGADTCGWR-GVGPASRNSGLHN--ITFRYDNCTTYLNPGGKHAIADAQNITISQYACHDQVAVTILWSPGALGIEFLKGFRVILEELKSEGRQCQQLILKDPKQLNSSFRRTGMESQPFLNMKFETDYFVKIVPFPSIKNESNYHPFFFRTRACDLLLQPDNLACKPFWKPRNLNISQHGSDMHVSFDHAPQNFGFRGFHVLYKLKHEGPFRRRTCRQDQNTETTSCLLQNVSPGDYIIELVDDSNTTRKAAQYVVKSVQSPWAGPIRAVAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESPESSTYAAALPRDRLRPQPKVFLCYSNKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQREWAIQKIHESQFIIVVCSKGMKYFVDKKNFRHKGGSRG-----------EAQGEFFLVAVAAIAEKLRQAKQSSSAALRKFIAVYFDYSCEGDVPCSLDLSTKYKLMDHLPELCAHLHSGEQ--EVLGQHPGHSSRRNYFRSKSGRSLYVAICNMHQFIDEEPDWFEKQFIPFQHPPVRYQEPVLEKFDSGLVLNDVISKPGPESDFCRKVEACVLGAAGPADSYSYLESQHVGLDQDTEAQPSCDSAPALQPLLHAVKAGSPSEMPRDSGIYDSSVPSSELSLPLMEGLSPDQIETSSLTESVSSSSGLGEEDPPTLPSKLLASG-VSR-EHGCHSHT--DELQALAPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFM7-1", "uniprot_id": "I17RD_HUMAN", "id": "Q8NFM7-1", "name": "Interleukin-17 receptor D", "aln": "MAPWLQLCSVFFTVNACLNGSQLAVAAGGSGRARGADTCGWR-GVGPASRNSGLYN--ITFKYDNCTTYLNPVGKHVIADAQNITISQYACHDQVAVTILWSPGALGIEFLKGFRVILEELKSEGRQCQQLILKDPKQLNSSFKRTGMESQPFLNMKFETDYFVKVVPFPSIKNESNYHPFFFRTRACDLLLQPDNLACKPFWKPRNLNISQHGSDMQVSFDHAPHNFGFRFFYLHYKLKHEGPFKRKTCKQEQTTETTSCLLQNVSPGDYIIELVDDTNTTRKVMHYALKPVHSPWAGPIRAVAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESSESSTYTAALPRERLRPRPKVFLCYSSKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQREWVIQKIHESQFIIVVCSKGMKYFVDKKNYKHKGGGRG-----------SGKGELFLVAVSAIAEKLRQAKQSSSAALSKFIAVYFDYSCEGDVPGILDLSTKYRLMDNLPQLCSHLHSRDHGLQEPGQHTRQGSRRNYFRSKSGRSLYVAICNMHQFIDEEPDWFEKQFVPFHPPPLRYREPVLEKFDSGLVLNDVMCKPGPESDFCLKVEAAVLGATGPAD--SQHESQHGGLDQDGEARPALDGSAALQPLLHTVKAGSPSDMPRDSGIYDSSVPSSELSLPLMEGLSTDQTETSSLTESVSSSSGLGEEEPPALPSKLLSSG-SCKADLGCRSYT--DELHAVAPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8QHJ9-1", "uniprot_id": "I17RD_DANRE", "id": "Q8QHJ9-1", "name": "Interleukin-17 receptor D", "aln": "MAGSRRLAHFFMAS--CLFLCYTASVNGG--KRGNSDKCSYKQGTQTSSMDEGARKLGVTFRYDNCSVNWSPLGKHAIHEVNNISFSHLSCDSQAAVVVHWMASPLGIEHVKGFRVYLEDKNPERKQCQHLILKDPRQLNFSYKTIRMSSQPFSSLAFETDYMVRIVPFPTFLNDSFFPPSFLRTNSCEVLLGPDNLVCKPFWKPKMLNVSQLGSNLHVVFDHAPSTFGFSIYYLYYKLRQEGPFRLKRCKPEQNGPKTTCVLQDVTPGTYAIELRDDSNNTRRQTQYHVSQVHSPWAGPIRAMAITVPLVIMSAFATLFTVMCRKKQQENIYSHLDEESSESSSQTTALSADRPWPRPKIFICYSSRDGAKHLAVIQSFAFFLQDFCGCEVSLDLWEHLEICKEGQMSWLSRRIDEAHFIITVCSKGLKHFVEKRHRKGKATSKEKNREPSASDSSSSSRDLFIVASAIISEKLKEVHQKS-SDLSRFMSVYFDYSHETDVPTSLSLAPKFKLMDQLPQLFARLHSRQLSLTDREPQPPNVSKRNYFCSKSGRSLYVAIYNMHQHVTQEPDWLEKELMP---PPLPNKRTIPEKVDSGLVLNEVKLKHGSESE-CPPVRSNVLILPQTPQVGVSLSLSREDLGEGSSSQ----DAGSCRPVLHTDGSASPPEMPRDSGIYDSSVPSSELSIPLMDGLSPDHADNSSLADSVSSSSGLGDEEPPAVSSLHCTAHTICKADLHHQHLHPSEGLIAAAST", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :*. .*:: ** . * . ** : .:*.*.:: *. .:* :.* : :**:****:. .* *** * :.:**::*: :*..*.**.: * ...****.:***** **: ..* : **:*:****:*** *:: *.**** .: *****:*::****:: *:* : * *:**.:*::** ****.*******: **::* **:::* *.*** .*** ::: ***::****: : *: :*. .*:*:**:*:** * *** **:*.**: :* :. *:*********:*******::***************************.***: ::.*. :* *:**:*:***.:** :*: *:*.**:***:******:*****.:. * *** .* ::*.*::***.*****:*:**:*: : *. .: .. ::*:** : *:***::.:*.* : * :*::****** * *** *.*:.*::***:**:* ::*** : :. : *:**** **:******** ****.: :****:**:::* **: :..: **.*******:* * *.**: * *.: :* . ..: . .: .*.:. .:: .. : :*:**: :.**.:******************:***:***.*: :.***::*********:*:**:..* :: .: : : : * * *. ", "identical_positions": 355, "similar_positions": 232, "identity": "46.83%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020402-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O75311-1", "uniprot_id": "GLRA3_HUMAN", "id": "O75311-1", "name": "Glycine receptor subunit alpha-3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSAR-------------SRSAPMSPSDFLDKLMGRTSGYDARIRP------------------------NFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSE-YPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAF---------------------------------------------------------------------------------------------------------------------------------------ALEKFYRFSDMDDEVRESRFSFT-AYGMGPCLQAKDG----------------MTPKGPNHPVQVMPKSPDEMRKVFID-------------------------------------------------------RAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91XP5-1", "uniprot_id": "GLRA3_MOUSE", "id": "Q91XP5-1", "name": "Glycine receptor subunit alpha-3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHVRHFRTLVSGFYFWEAALLLSLVATKETNSAR-------------SRSAPMSPSDFLDKLMGRTSGYDARIRP------------------------NFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSE-YPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAF---------------------------------------------------------------------------------------------------------------------------------------ALEKFYRFSDTDDEVRESRFSFT-AYGMGPCLQAKDG----------------VVPKGPNHAVQVMPKSPDEMRKVFID-------------------------------------------------------RAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24524-1", "uniprot_id": "GLRA3_RAT", "id": "P24524-1", "name": "Glycine receptor subunit alpha-3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHVRHFRTLLSGFYFWEAALLLSLVATKETNSAR-------------SRSAPMSPSDFLDKLMGRTSGYDARIRP------------------------NFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSE-YPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAF---------------------------------------------------------------------------------------------------------------------------------------ALEKFYRFSDTDDEVRESRLSFT-AYGMGPCLQAKDG----------------VVPKGPNHAVQVMPKSADEMRKVFID-------------------------------------------------------RAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHHQQD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9Q7Y2-1", "uniprot_id": "A0A8M9Q7Y2_DANRE", "id": "A0A8M9Q7Y2-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTRKRLRSVAAWGFIAWEIGILLSLVASKEPESPR-------------RRAAPMSPSDFLDKLMGRTSGYDARIRP------------------------NFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSE-YPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEKGPVQVADGLTLPQFILKDESDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRRRKKSGKTFDQTFDEEL------------------------------------------------------------------------------------------------------------AESLRRINGSRS-AEPVYGSMGQLDQTNDMEEEVRESRLSFTPNAGKDGAVPKTAN----------------NAATTPSEPAVAPGKSHEEMRKLFID-------------------------------------------------------RAKKIDTVSRAGFPLAFLFFNIFYWVLYKILRHEDVHKP--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94900-1", "uniprot_id": "GLUCL_DROME", "id": "Q94900-1", "name": "Glutamate-gated chloride channel", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSGHYFWAILYFASLCSASLANNAK-------------INFREKE-KKVLDQILG-AGKYDARIRPSG---------------------INGTDGPAIVRINLFVRSIMTISDIKMEYSVQLTFREQWTDERLKFDD-IQGRLKYLTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRFTL-EKFLTDYCNSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSGSNKANMHKENMKKKRRD--------------------------------------------------------------------------------------------------------------------------------------LEQASLDAASDLLDTDSNATFAMKPLVRHPGDPLALEK----------------RLQCEVHMQAPKRPNCCKTWLSKFPTRQ---------------------------------------------------CSRSKRIDVISRITFPLVFALFNLVYWSTYLFREEEDE-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDU9-1", "uniprot_id": "Q9VDU9_DROME", "id": "Q9VDU9-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVFQIIILVICTICMKHY-------------AKGEFQQSLAITDILPEDIKRYDKMRPP------------------------KKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLPENMTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQWDPTTPLVVDENIELPQVALIRNETAD-CTQVYSTGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPIPKPMAYPPKPVAGDGPKKEGEGA------------------------------------------------------------------------------------------------------------PPGGSNSTASKQQATMLPLADEKIEKIEKIFDEMTKNRRIVTTTRRVVRPPLDADGPWIPRQESRIILTPTIAPPPPPPQPAAPEPELPKPKLTPAQER----------------------------------------------------LKRAIYIDRSSRVLFPALFASLNGIYWCVFYEYL---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PI70-1", "uniprot_id": "M9PI70_DROME", "id": "M9PI70-1", "name": "", "aln": "MGCVFEAAKEQPHKPRSRQLRRNQCRGKAEKAAAGTRGKVAVRGNNDKPAEDIKIKDNYQQNHKTQTETQTEVAAVVAIATDAGAETETETEAEAQKEPATGPEHLKAAAQVLLTIRQARQENNKHSSSQVAETHKDEGEDALARQGSIVDTAAGRIGIDIAATTIQVAERHEDGQHWQQHNVRRRRRQPDPAAHPASITKLSAISLHFHALAALAKTLQKHEDLSPVQDRQPLAYRAWQEHPYAETQMPATMSAAIIANVGATAAATSAAAFQYLGQHYKHYSQSISFYAASSVLLMLCYLTTASTAAATQSETGALDKHPIHGIDWSKFDESSSDKEILDLLLEKKRYDKRLLPPVNDEDFCCGLQSPDMATNQNARRPHNRGTLTVNVNVLLLSLASPDESSLKYEVEFLLNQQWNDPRLQYGN-KSHYDFLNALHHHDSIWTPDTYFIMHG-DFKDPIIPMHFALRIFRNGTITYAMRRHLILSCQGSLHIFPFDDPKCSFSMESISYEEAQIKYVWKNDEDTLRKSPSLTTLNAYLIKNQTTACDQNSWRGNYSCLQVELTFTRDRAYYFTTVFIPGIILVTSSFITFWLEWNAVPARVMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMNVWDGVCMCFIYASLLEFVCVNYVGRKRPLHNVVYRPGENPVTQRLPAVLSRIGVILASPLASAAATPAMSMMGGATPMSSGTPAASSSVATPGTPRITDPEEFFGGGMRWQEAHGGIIGAAVQNLRARSIKRKAARSPSTSISPHPSGRPTEHIYEEPGGSTSGVTSTKVKFKDELKEEQPEEAESSTKLRRSVATSTPALVVRIEAEIDPEAEDKPIQDMEMTERQLSLPLKPPRRKASRSNSPASVYSDAFENVEATPGEKRQNAGAPNEIVACTTCGGSNSPCTHSANNGCATETCFVQVRKKEPPHPIRVAKTIDVIARITFPTAYAIFLIFFFVHYKGFS---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . : ** * . * :: : .: : : .: * .:. : : *.* ** : . :* ** :* . : : : :: : .: * :: * *:* .: :* * * : : * . :: : *. . . : * . *:::*::* : : * **. :** ::* *:::**:. *.**** :*:*::*.: * .::** ** .*:: : .** *:: :*:*: :* . . . . . . . . : ** :* ** : : .:: : ", "identical_positions": 60, "similar_positions": 104, "identity": "6.07%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020402-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0AC58JH78-1", "uniprot_id": "A0AC58JH78_DANRE", "id": "A0AC58JH78-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWPERERKSRRPPLHTHTHTHTHTHTRTRIVVSQPVSGCCAQSDGSGGETRVHQNGRPAPQKHICSLKFSHGTPEKQLLNSERMFSVIWRILLELLLVCWMFEGVIRCVFSKELKSPSVRTKPMSPSDFLDKLMGKTSGYDARIRP----------------------NFKGP--PVNVTCNIFINSFGSITETTMDYRLNVFLRQQWNDPRLAY-KEYPDDSLDLDPS--MLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQNGNVLYSIRLTLILSCPMDLKNFPMDTQTCTMQLESFGYTMNDLIFQWLDEGP-VQVADDLMLPQFVLKEEKDLGYCTKHYN--------TGKFTCIEVKFHLERQMGYYLIQMYIPSLLTVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR-------QYKEF-------------------------------------------------------------------------------------FRLRRKLRQEQRNRAASGQAGAAETKNKSNNVTGG--------TPSRNAQRQCSACAREEQLASQNQDLYFPGFGIDTS---LSG-DGPLSEAAAMFAGL------------------------------------------------------------------PPGHALFD---IRRRFVEQAKR-------IDTISRAVFPLSFLVFNVFYWVTYKVLRNEDIHLALRP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q61603-1", "uniprot_id": "GLRA4_MOUSE", "id": "Q61603-1", "name": "Glycine receptor subunit alpha-4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTTLVPASLFLLLWTLPGKVLLSVALAK--------EDVKSGLKGSQPMSPSDFLDKLMGRTSGYDARIRP----------------------NFKGP--PVNVTCNIFINSFGSVTETTMDYRVNVFLRQQWNDPRLAY-REYPDDSLDLDPS--MLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLESFGYTMNDLMFEWLEDAPAVQVAEGLTLPQFILRDEKDLGYCTKHYN--------TGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR-------QHKEF-------------------------------------------------------------------------------------MRLRRRQRRQR----------------------------------------------MEEDIIRESR-FYFRGYGLGHC---LQARDGGPMEGSSIYSPQ------------------------------------------------------------------PPTPLLKEGETMRKLYVDRAKR-------IDTISRAVFPFTFLVFNIFYWVVYKVLRSEDIHQAL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q94900-1", "uniprot_id": "GLUCL_DROME", "id": "Q94900-1", "name": "Glutamate-gated chloride channel", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSGHYFWAILYFAS--LCSASLAN---------NAKINFREKE----KKVLDQILG-AGKYDARIRPSGI-------------------NGTDG--PAIVRINLFVRSIMTISDIKMEYSVQLTFREQWTDERLKF-DDIQGRLKYLTLT--EANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDP-VQVVKNLHLPRFTL-EKFLTDYCNSKTN--------TGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSGSNKANMHKEN-------------------------------------------------------------------------------------MKKKRRDLEQAS-------------------------------------------LDAASDLLDTDSNATFAMKPLVRHPGDPLALEKRLQCEVHMQAPK------------------------------------------------------------------RPNCCKTWLSKFPTRQCSRSKR-------IDVISRITFPLVFALFNLVYWSTYLFREEEDE------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDU9-1", "uniprot_id": "Q9VDU9_DROME", "id": "Q9VDU9-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVFQIIILVICTICMKH--------------YAKGEFQQSLAITDILPEDIKRYDKMRPP----------------------KKEGQ--PTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLPENMTQEYRLLEVD--WLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQWDPTTP-LVVDENIELPQVALIRNETAD-CTQVYS--------TGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPIPKPMAYPP-------------------------------------------------------------------------------------KPVAGDGPKKEGEGAPPGGSNSTASKQQ-ATMLPL--------ADEKIEKIEKIFDEMTKNRRIVTTTRRVVRPPLDADGPWIPRQESRIILTPTIAPPP------------------------------------------------------------------PPPQPAAPEPELPKPKLTPAQERLKRAIYIDRSSRVLFPALFASLNGIYWCVFYEYL----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W4G1-1", "uniprot_id": "Q9W4G1_DROME", "id": "Q9W4G1-1", "name": "pH-sensitive chloride channel 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEW------SLIISILLNCLYASASALD---------EDCPTLDDGDSLSQTQLLDRLTH-GCRYDRLERPITY-------------------SETGQRLPVDVYMRAYIYFMQNLEAHDLQFKIYALLQMRYLDPRLNFRNVSPKRRQPILGEEHLRNSLWMPHIFLANERDSSILGLTEKDILTSISPDGTVIVSNRIKATLYCWLNLKKFPFDEQHCSTVLESWMYNTSELVLHWEQKRP-ITYDGALHLTEFVLQRSWSNETVINADLSDLRHGAFAGNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITLGTSTLLTFITLASAQGKTLPKVSYIKVSEVWFLGCTIFIFGSMVEFAFVNTIWRRKKSVPVKKLNS-------------------------------------------------------------------------------------KHILKSTLSPNLLRRRSHARSRSFSGTALHKTADTGSLGGAGFNNYLTVNLPITTIKEGQ-VLDQQRTSRVVQKMDVNFVESAFGSMGSAQSTGAISAASSSQ-----------------------------------------------------------TLTNNNRTESAGHQEEIDLSGWTTLTPQEIAMWIDSRARFVFPLSFLVFNLFFWTFVYCI-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VVH4-1", "uniprot_id": "Q9VVH4_DROME", "id": "Q9VVH4-1", "name": "pH-sensitive chloride channel 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMNLHLSEIFW------ITLILVLSIWTSVGVKAEE---------EECPSMADAGSLQQTQLIQRLTH-VCRYDRLERPFEY-------------------DSDGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFN--RSDNILGQKHLSERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLESWMYNTSDLILEWEPHTP-ISFDPEMRLTEYNMAQFWHNTTIVQSDGDNLRHGAFAGNYSSLSFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSYIKVSEVWFLGCTFFIFGSLVEFAFVNTIWRRKENIELKKVNS-------------------------------------------------------------------------------------KYIIKSTLTPRPARRQIGG---SLSNESRARSCSS-------LDNIVSS---TESVRNGNGTVNQGFNNYLTVHPNLPIIRTEC----AEADTVSICSAR----------------------------------------------------------------TNNDHIVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNALYWTFVYVL-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9Y4-1", "uniprot_id": "PHCL2_DROME", "id": "Q9V9Y4-1", "name": "pH-sensitive chloride channel 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDTLGIFVLISYLGLSSAAGVHLGDLQQNLAANGSVVVSPLNTTDAFSVSINLSQS----TVNNCPSLKNAESMALMELLTRLTA-PCRYDRMVPPVVH-------------------NKDGEEVPMDIYARFYIYVMKNLDSSDLQFTVQGLLQLRYLDPRLAFSSYLPNRRQPIMGESELKKMLWVPHIFLTNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKCKTTLESWMYNTTLVQLHWETDNP-VSFDKQLQLTEYNLIGSLYNESIRVSNESYMSHGSLEGNYSIISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMKVSYVTMSEVWFLVCTIFIFGSLVEFAFVNTIWRRNNDLQLKKRTT-------------------------------------------------------------------------------------KYIVKSTFVPHLKKHRRHG---------YRRTDST-----------------MSTMSTTSMDKTCGPNNTVITIETPIIIGGSLS---REDSAISLDEQD-----------------------------------------------------------------ETSTSESSDSSKEKPAQTFATMTPKEVSLWIDRKMRFVFPLSFIVFNALFWTLVYCL-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PI70-1", "uniprot_id": "M9PI70_DROME", "id": "M9PI70-1", "name": "", "aln": "MGCVFEAAKEQPHKPRSRQLRRNQCRGKAEKAAAGTRGKVAVRGNNDKPAEDIKIKDNYQQNHKTQTETQTEVAAVVAIATDAGAETETETEAEAQKEPATGPEHLKAAAQVLLTIRQARQENNKHSSSQVAETHKDEGEDALARQGSIVDTAAGRIGIDIAATTIQVAERHEDGQHWQQHNVRRRRRQPDPAAHPASITKLSAISLHFHALAALAKTLQKHEDLSPVQDRQPLAYRAWQEHPYAETQMPATMSAAIIANVGATAAATSAAAFQYLGQHYKHYSQSISFYAASSVLLMLCYLTTASTAAATQSETGALDKHPIHGIDWSKFDESSSDKEILDLLLE-KKRYDKRLLPPVNDEDFCCGLQSPDMATNQNARRPHNRGTLTVNVNVLLLSLASPDESSLKYEVEFLLNQQWNDPRLQYGNKSHYDFLNALHH---HDSIWTPDTYFIMHG-DFKDPIIPMHFALRIFRNGTITYAMRRHLILSCQGSLHIFPFDDPKCSFSMESISYEEAQIKYVWKNDEDTLRKSPSLTTLNAYLIKNQTTACDQNSWR---------GNYSCLQVELTFTRDRAYYFTTVFIPGIILVTSSFITFWLEWNAVPARVMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMNVWDGVCMCFIYASLLEFVCVNYVGRKRPLHNVVYRPGENPVTQRLPAVLSRIGVILASPLASAAATPAMSMMGGATPMSSGTPAASSSVATPGTPRITDPEEFFGGGMRWQEAHGGIIGAAVQNLRARSIKRKAARSPSTSISPHPSGRPTEHIYEEPGGSTSGVTSTKVKFKDELKEEQPEEAESSTKLRRSVATSTPALVVRIEAEIDPEAEDKPIQDMEMTERQLSLPLKPPRRKASRSNSPASVYSDAFENVEATPGEKRQNAGAPNEIVACTTCGGSNSPCTHSANNGCATETCFVQVRKKEPPHPIRVAKTIDVIARITFPTAYAIFLIFFFVHYKGFS----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : ** * . : . : : . : : : : * ** . :* *. :: . : : .: : * * .: :* * *. : * : * : : . : *::: :.. . : * :*. ::* : * *:::**:. *.* :* :::*.: * .* ** . : : * *:: :::*: :* . : . ** * ** : : .:: ", "identical_positions": 40, "similar_positions": 79, "identity": "3.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020402-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LX95-1", "uniprot_id": "F1LX95_RAT", "id": "F1LX95-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------MAVSAPP-VISATSTSAGVPGGLFRAEP---------------------LYSSPGEPPRLTPNMIN----------------------SFMASNHNGSVVGGGIGGGSGGTSNTNTNECRMVDMHGVKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQM---TRKQAVNSSRPGRPPKRSLG-VLQDNARLLPH--------------------------------------------------AVPGLLSPGLITP---TGITAAAMAEAMKLQKMKLMAMNTLQGNGSQNGTESEPDDLNSTTGGSESSWDKEKIQSPLAAPGAQHGIAHAALAGQ-PGLGGAPTLNPLQQNHLLSNRLDLPFMMMP-------------HPLLPVSLPPASVAMAMNQMNHLN---------TIANMAAAAQIHSPLSRAGASVIKERIPESPSPAPSLEESHRPGSQTSSHPSSSVSSSPSQMDHQSERMVMMPNNREEIIIDQDNGQSIKKFQRDNKDIQLSQHHLLNTFLHWIELAPL--------SKKSLLHQKEVPAQIPMMKSPLDKIQLAPGQALPPGFPGPFIFADSLSSVETLLTNIQVNNISINKINGLLKVALDNARIQEKQIQQEKKELRIELYREREIRENLERQLAVELQSRSTMQKRLKKEKKAKRKLQEALEFESKRRE------------------------------QVEQALKQATSGDSGLRMLKDSGIPDIEIENSGTPHDSAAMQGGNYYCLAMAQQLCSA--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q925Q8-1", "uniprot_id": "DACH2_MOUSE", "id": "Q925Q8-1", "name": "Dachshund homolog 2", "aln": "--------------------------------------------------------------------------------------------------MAVSAPP-VISATSSSAGVPGGLFRAEP---------------------LYSSPGEPPRLTPNMIN----------------------SFMANNHNGSVLGGGIGGGSGGSSNTNTNECRMVDMHGVKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQM---TRKQAVNSSRPGRPPKRSLG-VLQDNARLLPH--------------------------------------------------AVPGLLSPGLITP---TGITAAAMAEAMKLQKMKLMAMNTLQGNGSQNGTESEPDDLNSTTGGSESSWDKDKIQSPLAASGPQHGIAHAALAGQ-PGLGGAPTLNPLQQNHLLSNRLDLPFMMMP-------------HPLLPVSLPPASVAMAMNQMNHLN---------TIANMAAAAQIHSPLSRAGASVIKERIPESPSPAPSLEESHRPGSQTSSHPSSSVSSSPSQMDHHSERMVMMPNNREELIVDQDNGQSIKKFQRDNK--------------------------------------EEVPAQIPVMKSPLDKIQLAPGQALHPGFPGPFIFADSLSSVETLLTNIQG----------LLKVALDNARIQEKQIQQEKKELRIELFREREIRENLERQLAVELQSRSTMQKRLKKEKKAKRKLQEALEFESKRRE------------------------------QVEQALKQATSGDSGLRMLKDSGIPDIEIENSGTPHDSAAMQGGNYYCLAMAQQLCSA--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96NX9-1", "uniprot_id": "DACH2_HUMAN", "id": "Q96NX9-1", "name": "Dachshund homolog 2", "aln": "--------------------------------------------------------------------------------------------------MAVSASP-VISATSSGAGVPGGLFRAEP---------------------LYSTPREPPRLTPNMIN----------------------SFVVNNHSNSAGGGGRG-------NTNTNECRMVDMHGMKVASFLMDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDISPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLFTDCTNARRKRQM---TRKQAVNSSRPGRPPKRSLG-VLQENARLLTH--------------------------------------------------AVPGLLSPGLITP---TGITAAAMAEAMKLQKMKLMAMNTLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQ-PGIGGAPTLNPLQQNHLLTNRLDLPFMMMP-------------HPLLPVSLPPASVAMAMNQMNHLN---------TIANMAAAAQIHSPLSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERM------------------------------------------------------------------EEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQG----------LLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRRE------------------------------QVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNYYCLEMAQQLYSA--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T9A7-1", "uniprot_id": "A0AB32T9A7_DANRE", "id": "A0AB32T9A7-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------MAVSATPPVLSPTSTPGGAS--LFRPDS---------------------LYSSPAESPRLTSSMIN----------------------SFITG--GGSTNGNGPG-------GVHNNECKMVEVHGVKVASFTVDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDICPVVCTVEQVRILRGLGAIQPGVNRCKLITRKDFETLYNDCTNA----------------SSRPGRPPKRSLGVAMQDSSRLLPH--------------------------------------------------SVHGLLSPGLLSP---TGLTAAAMAEAMKLQKMKLMAMNNIHGAGSQNGTESENEELNSSAGGSESSWDKEKLQSPPSS-GAQHGLAHAALSAQ-HGLSGS-HLSSLQQSHLLANRLDLPFMMMP-------------HPLLPVSLPPASVAMAMNQMNHLN---------TIANMAAAAQMHSPLSRAGASVIKECVQDSPSPTPSLEEAPRPGSQPSSHPSSSVSSSPNPHTQSPERLVLNPTDGDLP--ERDTGINMKKMLKEK---------------------------------------DEAQITLPMQKPGFEKLPLGT-QTLPPGFPAPFLFADGLSSVETLLTNIQAAQG-------LLKVAVDNARVQEKQVQQERKELKMELYREREMRESLERQLTSELHSRATIQKRLKKEKKAKRKLQEALEFESKRRE------------------------------QVEQALKQATSPESLRMSLNEAVIPEVKSEHNGNQQENSSVQENRPYSKPPIMY------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IP19-1", "uniprot_id": "Q8IP19_DROME", "id": "Q8IP19-1", "name": "", "aln": "MDSVTSEQSENNNNKAGAINNNINSGIERAAGNMNTTAMLMHHQQQQQAAAAAAAAAAQQQQQQHNGRDGSNSSRGANEDRPNGRSSHTGRGSSCSPASSPSRHPSAVSPVSSLNHSMMQQMQQQQQQQQQQQQQQQHHQLSPPPHGMPSGNGLPTGLPPRMPHGLPPHSLGLLNSLQMMHHASPLELMAAAHHHVPPRSYNSPPPISTSDPSANECKLVEYRGQKVAAFIISNETMLCLPQAFELFLKHLVGGLHTVYTKLKRLDIVPLVCNVEQVRILRGLGAIQPGVNRCKLLCCKDFDILYRDCTTARCLSIKPPESNSLQFRSSRPGRPPKRGPVGLSLPPTHLSQHPQLKKHRLDNGDYAYENGHISDMKSPLLANGYNPPPINHMAFMQMNAHHPGAAALMSPGMPPHGLHARPESQMLKAAAQNAGMSAANMDALARSGIWENCRAAYEDIVKHLERLREERTDERQQAMGVGGAVVDRVGNVMVAEHKPRDLSSRNCSPTRQSPVLNLSKSGGNTDHGGSNCDAGSERSDCHSVAGSPARGGSRSLDEGSRSGVGGGVASHVGGGIIGVEDDEEEEENLSDENQSEVDERCLAKDDEDLSDTERDNLSTGSAAAAAAAAAAAAHQLHQHAASHHHQTVGLSHLGVVPPHQRGSPSSAEAAAAALQHQRALNYSQLAAAAAVANGAAVGGGAVANGPTGGGGALTPNEALLAANDAAALAGGLALGP-LGIDAHAAVPASSTETLLRNIQS----------LLKVAADNARQQERQISYEKAELKMDVLREREVKDSLERQLVDERKLRVLYQKRFRRERKIRIRYQQQLGGGSGAVKGSPNANGSGGGGSGSACSESEACGGGGGDAKCNNNNNNNNNNNNSNSSSHGGDVETMKENDAGSEKSDKSLASNSSCDVTAGHSAGSVSGSISAGLNCPDSPTHFKREPSSDHEGSVERQPRSSAASLAAHDEDNTKRCGSRDRDERPPSGSAASVAAEGSLAAAAAAAAAAAAAAASNGKGPWSYPGIDLMATGAFWQNYSESLAQELEMERKSRAANAERDVKSPLSERPTAYYKNSVLFGSAN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * .:*..*: :: : : * .. *.. * : .::. . . . ***::*: :* ***:* :..: ::****.*:********************** *:**.**********************: ***: *: ***.* **********. ::* * .. .*:***: . : : : * : *. *: : * :. .: ::: . ... .:: *: . . . :.:. :: : .: .. :*. :* . *.: . .* :: .. . :. * .: : .. ** . * :.* . . * * . .: .:: .:::.:::. : . . : * :* . : * **.**** *** ***** **** **:*:. *: **:::: ****:::.*****. * : * ***:::*:* : : *: * * : : :: :: .. :. : : :: :. *. :.. :: . ", "identical_positions": 155, "similar_positions": 178, "identity": "14.19%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020402-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M0Y6-1", "uniprot_id": "F1M0Y6_RAT", "id": "F1M0Y6-1", "name": "", "aln": "---------------------------------MAVPAALIPPTQLVPPQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASSASSSAATTVTSPGGGG--SGGGGGSGGNGGGGGG----SNCNPSLAAGSN---GGGGGVSAGGGGASSTPITASTGSSSSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGKPVYSTPSPVENTPQNNECKMVDLRGAKVASFTVEGCELICLPQAFDLFLKHLVGGLHTVYTKLKRLEITPVVCNVEQVRILRGLGAIQPGVNRCKLISRKDFETLYNDCTNA----------------SSRPGRPPKRTQSVTSPENSHIMPH--------------------------------------------------SVPGLMSPGIIPP--------TGLTAAAAAAA---NAAIAEAMKVKKIKLEAMSNYHASNNQHGADSENGDMNSSVGSSGGSWDKETLHSPPSQGSQAPVAHARIPAAYSLPVSHPLNHLQHSHLPPNGLELPFMMMPHPLIPVSLPPASVTMAMSQMNHLSTIANMAAAAQVQSPPSRVETSVIKERVPDSPSPAPSLEEGRRPGSHPSSHRSSSVSSSPARTESSSDRIPVHQNGLSMNQMLMGLSPN-VLPGPKEGDLAGHDMGHESKRIHIEKDETPLSTPTARDS----------------------MDKLSLAGHGQPLPPGFPSPFLFPDG-----LSSIETLLTNIQGLLKVAIDNARAQEKQVQLEKTELKMDFLRERELRETLEKQLAMEQKNRAIVQKRLKKEKKAKRKLQEALEFET-----------------------------------------------------------------KRREQAEQTLKQAASADSLR----------------------------------------------------------------------------------------------------------------------VLNDSLTPEIEADRSGGRADAERTIQD-----GRLYLKTTVMY----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYB2-1", "uniprot_id": "DACH1_MOUSE", "id": "Q9QYB2-1", "name": "Dachshund homolog 1", "aln": "---------------------------------MAVPAALIPPTQLVPPQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASSASSSAAATVTSPGGGGGGSGGGGGSGGNGGGGG-----SNCNPSLAAGSS---GGG--VSAGGGGASSTPITASTGSSSSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGKPVYSTPSPVENTPQNNECKMVDLRGAKVASFTVEGCELICLPQAFDLFLKHLVGGLHTVYTKLKRLEITPVVCNVEQVRILRGLGAIQPGVNRCKLISRKDFETLYNDCTNA----------------SSRPGRPPKRTQSVTSPENSHIMPH--------------------------------------------------SVPGLMSPGIIPP--------TGLTAAAAAAAAATNAAIAEAMKVKKIKLEAMSNYHASNNQHGADSENGDMNSSVGSSGGSWDKETLHSPPSQGSQAPVAHARMPAAFSLPVSHPLNHLQHSHLPPNGLELPFMMMPHPLIPVSLPPASVTMAMSQMNHLSTIANMAAAAQVQSPPSRVETSVIKERVPDSPSPAPSLEEGRRPGSHPSSHRSSSVSSSPARTESSSDRIPVHQNGLSMNQMLMGLSPN-VLPGPKEGDLAGHDMGHESKRIHIEKDETPLSTPTARDS----------------------IDKLSLTGHGQPLPPGFPSPFLFPDG-----LSSIETLLTNIQGLLKVAIDNARAQEKQVQLEKTELKMDFLRERELRETLEKQLAMEQKNRAIVQKRLKKEKKAKRKLQEALEFET-----------------------------------------------------------------KRREQAEQTLKQAASADSLR----------------------------------------------------------------------------------------------------------------------VLNDSLTPEIEADRSGGRADAERTIQD-----GRLYLKTTVMY----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UI36-1", "uniprot_id": "DACH1_HUMAN", "id": "Q9UI36-1", "name": "Dachshund homolog 1", "aln": "---------------------------------MAVPAALIPPTQLVPPQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSS---SCGPLPGKPVYSTPSPVENTPQNNECKMVDLRGAKVASFTVEGCELICLPQAFDLFLKHLVGGLHTVYTKLKRLEITPVVCNVEQVRILRGLGAIQPGVNRCKLISRKDFETLYNDCTNA----------------SSRPGRPPKRTQSVTSPENSHIMPH--------------------------------------------------SVPGLMSPGIIPP--------TGLTAAAAAAAAATNAAIAEAMKVKKIKLEAMSNYHASNNQHGADSENGDMNSSVGSSDGSWDKETLPSSPSQGPQASITHPRMPGARSLPLSHPLNHLQQSHLLPNGLELPFMMMPHPLIPVSLPPASVTMAMSQMNHLSTIANMAAAAQVQSPPSRVETSVIKERVPDSPSPAPSLEEGRRPGSHPSSHRSSSVSSSPARTESSSDRIPVHQNGLSMNQMLMGLSPN-VLPGPKEGDLAGHDMGHESKRMHIEKDETPLSTPTARDS----------------------LDKLSLTGHGQPLPPGFPSPFLFPDG-----LSSIETLLTNIQGLLKVAIDNARAQEKQVQLEKTELKMDFLRERELRETLEKQLAMEQKNRAIVQKRLKKEKKAKRKLQEALEFET-----------------------------------------------------------------KRREQAEQTLKQAASTDSLR----------------------------------------------------------------------------------------------------------------------VLNDSLTPEIEADRSGGRTDAERTIQD-----GRLYLKTTVMY----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NA80-1", "uniprot_id": "A0A8M1NA80_DANRE", "id": "A0A8M1NA80-1", "name": "", "aln": "---------------------------------MATPAALLPATPMAH-APPMSISAVVN----SSTPATLSPSPSVTP---AGPSLFRTELLSS-----------------------------------------ASPGIP---------------------------------------------------------IGSLPHKPVYSTPSPVENTPQNNECKMVEVRGAKLASFTVNGNELICLPQAFDLFLKHLVGGLHTVYTKLKRLEITPVVCNVEQVRILRGLGAIQPGVNRCKLISRKDFEVLYNDCTNA----------------SSRPGRPPKRTQNVTSPDSPHVLPH--------------------------------------------------SVSGLMSSGLMSH--------TGLTAAT----------LAEAMK-KKIKLEVMNSYHGNNN-HSADSENGDITSSMG----------------------------------------------------LELPFMMMPHPLIPVSLPPASVTMAMNQMNHLSTIASMAAAAQVQSVPSRMVTSVIKERVPDSPSPVPSLDDGRRSGSHLSSRQSSSVSSSPAHTESSSDRPHLHQNGLSLGHALLGLSPS-APPGPKEGDLATHDTVHETKRASTEKEENVLCTPTSRDS----------------------YERLSHS--GPTLPPGFPAPLLFPEG-----LSSIETLLTNIQGLLKVAIDNARAQEKQVQLERTELKMELYRERELRETLERQLCVEQKNRALIQKRLKKEKKTKRKLQEALEVES-----------------------------------------------------------------KRRDHAEQTLQRTTSCERSP----------------------------------------------------------------------------------------------------------------------IHNDSQQ-ELETIHNTSKTDTERTIQD-----GRLFLKSTMMY----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IP19-1", "uniprot_id": "Q8IP19_DROME", "id": "Q8IP19-1", "name": "", "aln": "MDSVTSEQSENNNNKAGAINNNINSGIERAAGNMNTTAMLMHHQQQQQAAAAAAAAAAQQQQQQHNGRDGSNSSRGANEDRPNGRSSHTGRGSSCSPASSPSRHPSAVSPVSSLNHSMMQQMQQQQQQQQQQQQQQQHHQLSPPPHG-------MPSGNGLPTGLPPRMPHGLPPHSLGLLNSLQMMHHASPLELMAAAHHHVPPRSYNSPPPISTSDPSANECKLVEYRGQKVAAFIISNETMLCLPQAFELFLKHLVGGLHTVYTKLKRLDIVPLVCNVEQVRILRGLGAIQPGVNRCKLLCCKDFDILYRDCTTARCLSIKPPESNSLQFRSSRPGRPPKRGPVGLSLPPTHLSQHPQLKKHRLDNGDYAYENGHISDMKSPLLANGYNPPPINHMAFMQMNAHHPGAAALMSPGMPPHGLHARPESQMLKAAAQNAGMSAANMDALARSGIWENCRAAYEDIVKHLERLREERTDERQQAMGVGGAVVDRVGNVMVAEHKPRDLSSRNCSPTRQSPVLNLSKSGGNTDHGGSNCDAGSERSDCHSVAGSPARGGSRSLDEGSRSGVGGGVASHVGGGIIGVEDDEEEEENLSDENQSEVDERCLAKDDEDLSDTERDNLSTGSAAAAAAAAAAAAHQLHQHAASHHHQTVGLSHLGVVPPHQRGSPSSAEAAAAALQHQRALNYSQLAAAAAVANGAAVGGGAVANGPTGGGGALTPNEALLAANDAAALAGGLALGPLGIDAHAAVPASSTETLLRNIQSLLKVAADNARQQERQISYEKAELKMDVLREREVKDSLERQLVDERKLRVLYQKRFRRERKIRIRYQQQLGGGSGAVKGSPNANGSGGGGSGSACSESEACGGGGGDAKCNNNNNNNNNNNNSNSSSHGGDVETMKENDAGSEKSDKSLASNSSCDVTAGHSAGSVSGSISAGLNCPDSPTHFKREPSSDHEGSVERQPRSSAASLAAHDEDNTKRCGSRDRDERPPSGSAASVAAEGSLAAAAAAAAAAAAAAASNGKGPWSYPGIDLMATGAFWQNYSESLAQELEMERKSRAANAERDVKSPLSERPTAYYKNSVLFGSAN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ..* *: .. : :* . . ..: . * : . . :. :. :* :. *.*. . *. ****:*: ** *:*:* :.. ::******:********************:*.*:*************************:. ***: **.***.* ********** * .*: * ....***.*: . *.**: * * . : .. . .: : :....: .::* . *.: . .* :: .. . :. . ... : . . . . :* .* .. . *. . . *: *::.* : ::: :**:. * : :*** . * :.*. : : : : : . *.:.:: . : * : . .*. *:. * :. ** **** ***.***** **** **:*:. *::****:. ****::::**:** *:* *.: ***:::*:* : : *: * : ::::::* :* : .:* *:* :. :::** ::. : *.:::: ", "identical_positions": 177, "similar_positions": 189, "identity": "16.27%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020415-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62869-1", "uniprot_id": "ELOB_MOUSE", "id": "P62869-1", "name": "Elongin-B", "aln": "-----------------------------------------------------------------------------------------------------------------------------MDVFLMIRRHKTTIFTDAKESSTVFELKR--------------IVEG--ILKRPPEEQRLY----------KDDQLLDDG--KTLGECGFT------------SQTARPQAP-----------ATVGLAFRADDTFEALRIEPFSS--------------PPELP---------------DVMKPQDSGGSANEQAVQ-------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15370-1", "uniprot_id": "ELOB_HUMAN", "id": "Q15370-1", "name": "Elongin-B", "aln": "-----------------------------------------------------------------------------------------------------------------------------MDVFLMIRRHKTTIFTDAKESSTVFELKR--------------IVEG--ILKRPPDEQRLY----------KDDQLLDDG--KTLGECGFT------------SQTARPQAP-----------ATVGLAFRADDTFEALCIEPFSS--------------PPELP---------------DVMKPQDSGSSANEQAVQ-------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QLV3-1", "uniprot_id": "A0A8M1QLV3_DANRE", "id": "A0A8M1QLV3-1", "name": "DDE Tnp4 domain-containing protein", "aln": "MELLQQNVAAAGRVIMDAIQAEWEPLSNWELDQRLDRAVEEMIEADLVAQVQEQINSAQQKDSADQTQTPKQSEPKQPVQESALQRSHATEVMEANPTVQYVTNFLQSSNMGYSKNRMSGRARLSMSHTVLLSLTLLSKRVSYRSVSSSFHLEKGNIHRIFFSFCDQVIAQQNRIIQWPTGQEAIQNLLPFSSWHSRSEGLEERGLPRVLGVLGDTRIPIRLPSGKPDSETDAPDAKKLKSEVHPDSWLNLELVCNGDGRFIYCHISKGSESDRGKALTERLQKHPEMLPPGACLIAGVGHPLTEQILTPFSTGRSPQENLYNRALGNHLGRFNQAVADLKERFQKLRYLDMGNFERAKTVVLTACVLHNVFLDMGDVTKGLIEKSAVKDVEELNQDAAGVKMRETVANLLYSSLEEGTL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. ::: : .. :. *: *.*:: *.: *:: *. :: : :.: * : * :.** * * *:* *:* .: *. ..*. * *. *. * ** :::.* .:* *.:*: : ", "identical_positions": 29, "similar_positions": 47, "identity": "6.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020416-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BZJ7-1", "uniprot_id": "DCNL2_MOUSE", "id": "Q8BZJ7-1", "name": "DCN1-like protein 2", "aln": "----------------------------------------MHKLKSA-QKDKVRQFMACTQASERTAIYCLTQNEWKLDEATDSFFQNPE-AFHRESMKSSVDQKKLEQLYSRYKDPQDENKIGIDGIQQFCDDLSLDPASISVLVIAWKF-RAATQCEFSKKEFVDGMTELGCDSTERLKALLPRLEQELKDPAK-FKDLYQFTFTFAKNPGQKGLDLEMAVAYWKLVLSGRF------KFLDLWNTFLLEHHKRSIPRDTWNLLLDFGN---MIADDLSNYDEEGAWPVLIDDFVEYAR------------------PVVTGGRRSPF---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0U1RRP2-1", "uniprot_id": "A0A0U1RRP2_RAT", "id": "A0A0U1RRP2-1", "name": "DCN1-like protein", "aln": "----------------------------------------MHKLKSA-QKDKVRQFMACTQASEKTAIYCLTQNEWKLDEATDSFFQNPE-AFHRESMKSSVDQKKLEQLYSRYKDPQDENKIGIDGIQQFCDDLSLDPASISVLVIAWRF-RAATQCEFSKKEFVDGMTELGCDSTERLKALLPKLEQELKDSAK-FKDFYQFTFTFAKNPGQKGLDLEMAVAYWKLVLSGRF------KFLDLWNTFLLEHHKRSIPRDTWNLLLDFGN---MIADDLSNYDEEGAWPVLIDDFVEYAR------------------PVVTGGRRGPL---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PH85-1", "uniprot_id": "DCNL2_HUMAN", "id": "Q6PH85-1", "name": "DCN1-like protein 2", "aln": "----------------------------------------MHKLKSS-QKDKVRQFMACTQAGERTAIYCLTQNEWRLDEATDSFFQNPD-SLHRESMRNAVDKKKLERLYGRYKDPQDENKIGVDGIQQFCDDLSLDPASISVLVIAWKF-RAATQCEFSRKEFLDGMTELGCDSMEKLKALLPRLEQELKDTAK-FKDFYQFTFTFAKNPGQKGLDLEMAVAYWKLVLSGRF------KFLDLWNTFLMEHHKRSIPRDTWNLLLDFGN---MIADDMSNYDEEGAWPVLIDDFVEYAR------------------PVVTGGKRSLF---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GD41-1", "uniprot_id": "A0AC58GD41_DANRE", "id": "A0AC58GD41-1", "name": "DCN1-like protein", "aln": "MCVIFSLCMFVCVSFCLYTVLNVFLRLSEFMSEGISFVSTQHKLKSS-QKDKVRQFMSFTQAGEKTAVYCLTQNDWKLEVATDNYFQNPD-LYHKESMKSSVDRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLNLDPASISVLVVAWKF-RAATQCEFSKKEFIDGMTELGCDSPEKLRALLPRLEQDLKDSGK-FKDFYQFTFNFAKNPGQKGLDLEMAVAYWNLVLAGRF------KFLDLWNRFLLEHHKRSIPKDTWNLLLDFGN---MIADDMSNYDEEGAWPVLIDDFVEYAR------------------PIVTGSKRKTV---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUQ8-1", "uniprot_id": "DCNL1_DROME", "id": "Q9VUQ8-1", "name": "DCN1-like protein 1", "aln": "----------------------------------------MNKLKSSTHRDKVKKFISLTHTGEQTAIFCLQQNDWKFELASDNYFQNPE-YYYRE-----LDRKRIEQLFMRYRDPSDPLKIGSQGVIHFLEDLDLKPDSKLVLIIAWKF-HAEVQCEFSRDEFINGMCDLGIDSIDKLKTKLPILEQELNDAGK-FKDFYHFTFNYAKDPGQKGIDLEMAIAYWCIVLSGRF------KFLDIWCQFLEEKHKRAISRDTWNLLLDFAT---NIDDRMSNYDSEGAWPVLIDDFVEWCQENDHLKEDSSPASGYQQQSSASSSSQKNISSAYQTSHSTNMNYG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12395-1", "uniprot_id": "DCN1_YEAST", "id": "Q12395-1", "name": "Defective in cullin neddylation protein 1", "aln": "-----------------------------------MSNNKIKRKDASPEQEAIESFTSLTKCDPKVSRKYLQRNHWNINYALNDYYDKEIGTFTDEVSTVAHPPVYPKELTQVFEHYINNNLFDIDSLVKFIEELGYNLEDLATLCLAHLLGYKKLEEPLKREDFLSTWFMQGCSTISDMQECIKTLDVKLHEDLQYFTQIYNYAFNLILDPNRKDIDTDEGIQYWKLFFQPEYPVRMEPDLLEAWFRFLRDEGKTTISKDTWRMLLLFFKRYPTIQKIISDYDETAAWPFIIDEFYECLQ-----------------------DQQ------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .:: .:: :..* : *: . :.: * :*.*.:: * :.:::: * :.* :.. : :. :.: :* ::*. . . .* :* : : :.:.:*:. * .: . :: : *: .*:: : *.::*:::*. :*.:*.:* : .: ** :.: .: .:*: * ** :. * :*.:***.:** * . * . :*:**. .***.:**:* * : . : ", "identical_positions": 47, "similar_positions": 109, "identity": "13.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020416-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LJE4-1", "uniprot_id": "A0ABK0LJE4_RAT", "id": "A0ABK0LJE4-1", "name": "Triosephosphate isomerase", "aln": "MSSLIPGSFNLPMTIMELNSRKFFVGGNWKMNGKKKCLGELICTLNAAKMPADTEVVCAPPTAYIDFARQKLD-PKIAVAAQNCYKVTNGAFTGEISPGMIKDLGATWVVLGHSERRHVFGESDELIGQKVNHALSEGLGVIACIGEKLDEREAGITEKVVFEQTKAIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKCNVSEEVAQCTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48500-1", "uniprot_id": "TPIS_RAT", "id": "P48500-1", "name": "Triosephosphate isomerase", "aln": "MAP----------------SRKFFVGGNWKMNGRKKCLGELICTLNAAKLPADTEVVCAPPTAYIDFARQKLD-PKIAVAAQNCYKVTNGAFTGEISPGMIKDLGATWVVLGHSERRHIFGESDELIGQKVNHALSEGLGVIACIGEKLDEREAGITEKVVFEQTKAIADNVKDWCKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKCNVSEGVAQCTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60174-1", "uniprot_id": "TPIS_HUMAN", "id": "P60174-1", "name": "Triosephosphate isomerase", "aln": "MAP----------------SRKFFVGGNWKMNGRKQSLGELIGTLNAAKVPADTEVVCAPPTAYIDFARQKLD-PKIAVAAQNCYKVTNGAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSDAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17751-1", "uniprot_id": "TPIS_MOUSE", "id": "P17751-1", "name": "Triosephosphate isomerase", "aln": "MAP----------------TRKFFVGGNWKMNGRKKCLGELICTLNAANVPAGTEVVCAPPTAYIDFARQKLD-PKIAVAAQNCYKVTNGAFTGEISPGMIKDLGATWVVLGHSERRHVFGESDELIGQKVSHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVNDGVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q1MTI4-1", "uniprot_id": "TPISA_DANRE", "id": "Q1MTI4-1", "name": "Triosephosphate isomerase A", "aln": "MSS-----------------RKFFVGGNWKMNGDKESLGELIMTLNTASLNDETDVVCGAPSIYLDYARSKLD-QRIGVAAQNCYKVPKGAFTGEISPAMIKDCGIDWVILGHSERRHVFGESDELIGQKVAHCLESDLGVIACIGEKLEEREAGTTEDVVFEQTKVIADNVKDWTRVVLAYEPVWAIGTGKTASPEQAQEVHEKLRGWLRANVSDAVADSVRIIYGGSVTGGNCKELAAQADVDGFLVGGASLKPEFVDIINARS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P29613-2", "uniprot_id": "TPIS_DROME", "id": "P29613-2", "name": "Triosephosphate isomerase", "aln": "MSR------------------KFCVGGNWKMNGDQKSIAEIAKTLSSAALDPNTEVVIGCPAIYLMYARNLLP-CELGLAGQNAYKVAKGAFTGEISPAMLKDIGADWVILGHSERRAIFGESDALIAEKAEHALAEGLKVIACIGETLEEREAGKTNEVVARQMCAYAQKIKDWKNVVVAYEPVWAIGTGQTATPDQAQEVHAFLRQWLSDNISKEVSASLRIQYGGSVTAANAKELAKKPDIDGFLVGGASLKPEFVDIINARQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00942-1", "uniprot_id": "TPIS_YEAST", "id": "P00942-1", "name": "Triosephosphate isomerase", "aln": "MAR------------------TFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFVDIINSRN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .* ****:*:** ::.: *: *.:* : .:** *: *: :: . : .: :..**.* ..****** * :** * **:******* * *.* :*.:*. ..* ..: ** ****.*:*::** * .** .* . :::*** .**:*********** :*:*::**::* :* :* ::.. .: ** ****...... : :.*:*******************::.", "identical_positions": 107, "similar_positions": 79, "identity": "40.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020416-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LJE4-1", "uniprot_id": "A0ABK0LJE4_RAT", "id": "A0ABK0LJE4-1", "name": "Triosephosphate isomerase", "aln": "MSSLIPGSFNLPMTIMELNSRKFFVGGNWKMNGKKKCLGELICTLNAAKMPADTEVVCAPPTAYIDFARQKLD-PKIAVAAQNCYKVTNGAFTGEISPGMIKDLGATWVVLGHSERRHVFGESDELIGQKVNHALSEGLGVIACIGEKLDEREAGITEKVVFEQTKAIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKCNVSEEVAQCTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48500-1", "uniprot_id": "TPIS_RAT", "id": "P48500-1", "name": "Triosephosphate isomerase", "aln": "MAP----------------SRKFFVGGNWKMNGRKKCLGELICTLNAAKLPADTEVVCAPPTAYIDFARQKLD-PKIAVAAQNCYKVTNGAFTGEISPGMIKDLGATWVVLGHSERRHIFGESDELIGQKVNHALSEGLGVIACIGEKLDEREAGITEKVVFEQTKAIADNVKDWCKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKCNVSEGVAQCTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60174-1", "uniprot_id": "TPIS_HUMAN", "id": "P60174-1", "name": "Triosephosphate isomerase", "aln": "MAP----------------SRKFFVGGNWKMNGRKQSLGELIGTLNAAKVPADTEVVCAPPTAYIDFARQKLD-PKIAVAAQNCYKVTNGAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSDAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17751-1", "uniprot_id": "TPIS_MOUSE", "id": "P17751-1", "name": "Triosephosphate isomerase", "aln": "MAP----------------TRKFFVGGNWKMNGRKKCLGELICTLNAANVPAGTEVVCAPPTAYIDFARQKLD-PKIAVAAQNCYKVTNGAFTGEISPGMIKDLGATWVVLGHSERRHVFGESDELIGQKVSHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVNDGVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q90XG0-1", "uniprot_id": "TPISB_DANRE", "id": "Q90XG0-1", "name": "Triosephosphate isomerase B", "aln": "MSG-----------------RKFFVGGNWKMNGDKKSIEELANTLNSAKLNPDTEVVCGAPTIYLDYARSKLD-PNIDVAAQNCYKVAKGAFTGEISPAMIKDCGVKWVILGHSERRHVFGESDELIGQKVAHALENGLGVIACIGEKLDEREAGITEKVVFAQTKFIADNVKDWSKVVLAYEPVWAIGTGKTASPQQAQEVHDKLRQWLKTNVSEAVANSVRIIYGGSVTGGTCKELASQKDLDGFLVGGASLKPEFIDIINAKA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P29613-2", "uniprot_id": "TPIS_DROME", "id": "P29613-2", "name": "Triosephosphate isomerase", "aln": "MSR------------------KFCVGGNWKMNGDQKSIAEIAKTLSSAALDPNTEVVIGCPAIYLMYARNLLP-CELGLAGQNAYKVAKGAFTGEISPAMLKDIGADWVILGHSERRAIFGESDALIAEKAEHALAEGLKVIACIGETLEEREAGKTNEVVARQMCAYAQKIKDWKNVVVAYEPVWAIGTGQTATPDQAQEVHAFLRQWLSDNISKEVSASLRIQYGGSVTAANAKELAKKPDIDGFLVGGASLKPEFVDIINARQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00942-1", "uniprot_id": "TPIS_YEAST", "id": "P00942-1", "name": "Triosephosphate isomerase", "aln": "MAR------------------TFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFVDIINSRN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .* ****:*:** ::.: *: *.:* : ..*** *: *: :: . : :: :..**.* :.****** * :** *. **:******* * *.* :*.:*. .** :*: ** ****.*:*::** * .** * :::*** :**:*********** :*:*::**::* :* :* ::.. .: ** ****...... : .: *:**************:****:: ", "identical_positions": 109, "similar_positions": 76, "identity": "40.98%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020416-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJK7-1", "uniprot_id": "TBX6_RAT", "id": "D3ZJK7-1", "name": "T-box transcription factor TBX6", "aln": "MYHPRELYPSLGTGYRLGHPQPGADSTFPPALTEGYRYPDLDTSKLDCFLSGIEAAPHTLAAPPPLPLLPSALGPETAPPPPEALHSLPGVSLSLENQELWKEFSAVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVVPVDGARYRWQGQHWEPSGKAEPRLPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRATQLCSQHWG-GVASFRFPETTFISVTAYQNPRITQLKIAANPFAKGFRENGRNCKRERDARVKRKLRGPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVATEACG---------------------------------SGDTPGGP-------CDST-----LGGDIRD--------------------------------------------------------------SDPEPAP-----------TPQEAASASAP----------------PCGGPS--------------------------------------AEAYLLHPAAFHGAPSHLPART---------------------------------------------------PSFPEAP--DPGRPAPYSAAFLELQPGPG----------------SSAYQTTP-----------SVTPFAPHFIQG--------------------APFP---------------LPYP----------GPGGYLDMGSKQMY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70327-1", "uniprot_id": "TBX6_MOUSE", "id": "P70327-1", "name": "T-box transcription factor TBX6", "aln": "MYHPRELYPSLGTGYRLGHPQPGADSTFPPALTEGYRYPDLDTSKLDCFLSGIEAAPHTLAAAAPLPLLPSALGPETAPPPPEALHSLPGVSLSLENQELWKEFSAVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVVPVDGARYRWQGQHWEPSGKAEPRLPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRATQLCSQHWG-GVASFRFPETTFISVTAYQNPRITQLKIAANPFAKGFRENGRNCKRERDARVKRKLRGPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVATEACG---------------------------------SGDTPGGP-------CDST-----LGGDIRD--------------------------------------------------------------SDPEQAP-----------TPQEAASASAP----------------PCGGPS--------------------------------------AEAYLLHPAAFHGAPSHLPART---------------------------------------------------PSFAEAP--DPGRPAPYSAAFLDLQPGPG----------------GSAYQAAP-----------SVPSFAPHFIQG--------------------GPFP---------------LPYP----------GPGGYLDMGSKPMY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95947-1", "uniprot_id": "TBX6_HUMAN", "id": "O95947-1", "name": "T-box transcription factor TBX6", "aln": "MYHPRELYPSLGAGYRLGPAQPGADSSFPPALAEGYRYPELDTPKLDCFLSGMEAAPRTLAAHPPLPLLPPAMGTEPAPSAPEALHSLPGVSLSLENRELWKEFSSVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVIPVDGARYRWQGRRWEPSGKAEPRLPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRAAQLCSQHWG-GMASFRFPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRNCKRERDARVKRKLRGPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------PAATEAYG---------------------------------SGDTPGGP-------CDST-----LGGDIRE--------------------------------------------------------------SDPEQAP-----------APGEATAAPAP----------------LCGGPS--------------------------------------AEAYLLHPAAFHGAPSHLPTRS---------------------------------------------------PSFPEAP--DSGRSAPYSAAFLELPHGSG----------------GSGYPAAP-----------PAVPFAPHFLQG--------------------GPFP---------------LPYT----------APGGYLDVGSKPMY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JIS6-1", "uniprot_id": "TBX6_DANRE", "id": "Q8JIS6-1", "name": "T-box transcription factor TBX6", "aln": "MLG-VEMYPGLALG--------------PQRLSDCY-YRDRDVP---LYPSTCEMAAR---ALPPALLKPHANTDSPATPQ-------DSVRMELENAGLWKQFSTVGTEMIVTKKGRRMFPQLRVKLSGLNPSLRYILLLDIVPVDSSRYRFQDNSWQVVGGAEARLPDRVFIHPDSPATGEHWQNRTISFHRAKLTNNTLDAQGYIILHSLHRYQPRVHVIEARDVL--MWGRTQHSFTFPETQFITVTAYQNNKITELKINSNPFAKGFRENGMNCKKQREARLKRKITSSQEECLDIESCDPCDSTELLPQSVDLPSSALTIMNTALPITDSGFHTEVSSHPDQTDSDQTLVLEQAFLTSEMPSSMESQQQTTSETNVNNALMDETGQMMDLSGYTSSFPTPQLSSHTSVPQSSSMYSVVSSTQSSDLELPQASSISSPHSMPAYSSIPSAEYPGVNSSTAMPASTTSLSDSYPSISHSTSSHLLQSSSYHSLLPTDQSQDNLSPHTPTNPPFQSIPACQGTRLTIDSGQNQVDDGGLSSANATTPAVPNPTQTAFPFPPVQPNNDPDPTSPSCQSLPQSALPYQQVSQCNQIPTPSDPNTTPTAFPFPPSEQSTPNSIMVSSNPNTTAFPFPPVQQQLNLSTSGPSSFPVSQSSGLNAIPNPVHPTTGSFSFPSTSAIHQGPMQSVPNTLHPSTAYTFPSSLPKHTGPLPNPAPTSYPFPTPIPPGPHPLQSLTLPSSCSIPNTSQIQSTFPQSYHNPSFSHIPPQMANHSQITSQSFPPLQTSSAPQLLSQSSTHPQCPPPSNAYPAVAPTEIGTFPQLNSAAPYLPDVVLHPSILPSLDPSLSSSAPPSLYNPFPSYSLRLCQDPRSSLHLPLRHIYRQPQHAHGQGSYFDLGGRTVF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *:**.*. * * *:: * * : *.. : * * *.: * .* * * * ..*.. .* :.*** ***:**:******:** ****** **.::**:*. **::***::***.:***:*.. *: * **.******:********* ** .:.:****.****.***.:*::****:*:****:*::.* :: ** ** **** **:****** :**:*** :*********** ***::*:**:***: ..: *.:* : . * .** .* *:.* * : : ***: :* :* . :. * .*** : . ***:: : ** ** :: ***.. * ..:. * :* * ... ...* :.. .. .: *..: *** ** . *.*:*:*.: ::", "identical_positions": 188, "similar_positions": 124, "identity": "20.77%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020418-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61619-1", "uniprot_id": "S61A1_HUMAN", "id": "P61619-1", "name": "Protein transport protein Sec61 subunit alpha isoform 1", "aln": "-MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAIT--LFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRG--MEFEGAIIALFHLLATRTDKVR-ALREAFYRQNLPNLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLG-TWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKE---------QSEVGSMGALLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61621-1", "uniprot_id": "S61A1_RAT", "id": "P61621-1", "name": "Protein transport protein Sec61 subunit alpha isoform 1", "aln": "-MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAIT--LFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRG--MEFEGAIIALFHLLATRTDKVR-ALREAFYRQNLPNLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLG-TWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKE---------QSEVGSMGALLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61620-1", "uniprot_id": "S61A1_MOUSE", "id": "P61620-1", "name": "Protein transport protein Sec61 subunit alpha isoform 1", "aln": "-MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAIT--LFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRG--MEFEGAIIALFHLLATRTDKVR-ALREAFYRQNLPNLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLG-TWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKE---------QSEVGSMGALLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q90ZM2-1", "uniprot_id": "S61A1_DANRE", "id": "Q90ZM2-1", "name": "Protein transport protein Sec61 subunit alpha-like 1", "aln": "-MAIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAIT--LFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMIITIGQAIVYVMTGMYGDPSEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRG--TEFEGAIIALFHLLATRTDKVR-ALREAFYRQNLPNLMNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLG-TWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLDDPVHAVIYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEIFVKE---------QSEVGSMGALLF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32915-1", "uniprot_id": "SC61A_YEAST", "id": "P32915-1", "name": "Protein transport protein SEC61", "aln": "MSSNRVLDLFKPFESFLPEVIAPERKVPYNQKLIWTGVS--LLIFLILGQIPLYGIVSSETSDPLYWLRAMLASNRGTLLELGVSPIITSSMIFQFLQGTQLLQIRPESKQDRELFQIAQKVCAIILILGQALVVVMTGNYGAPSDLGLPICLLLIFQLMFASLIVMLLDELLSKGYGLGSGISLFTATNIAEQIFWRAFAPTTVNSGRG--KEFEGAVIAFFHLLAVRKDKKR-ALVEAFYRTNLPNMFQVLMTVAIFLFVLYLQGFRYELPIRSTKVRGQIGIYPIKLFYTSNTPIMLQSALTSNIFLISQILFQKYPTNPLIRLIG-VWG-IRPGTQGPQMALSGLAYYIQPLMSLSEALLDPIKTIVYITFVLGSCAVFSKTWIEISGTSPRDIAKQFKDQGMVINGKRETSIYRELKKIIPTAAAFGGATIGALSVGSDLLGTLGSGASILMATTTIYGYYEAAAKEGGFT-----KNLVPGFSDLM-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38353-1", "uniprot_id": "SSH1_YEAST", "id": "P38353-1", "name": "Sec sixty-one protein homolog", "aln": "MSGFRLIDIVKPILPILPEVELPFEKLPFDDKIVYTIFAGLIYLFAQFPLVGLPKATTPNVNDPIYFLRGVFGCEPRTLLEFGLFPNISSGLILQLLAGLKVIKVNFKIQSDRELFQSLTKVFAIVQYVILTNIFIFAGYFG--DDLSVVQIGLINFQLVGAGIFTTLLAEVIDKGFGFSSGAMIINTVVIATNLVADTFGVSQIKVGEDDQTEAQGALINLIQGLRSKHKTFIGGIISAFNRDYLPNLTTTIIVLAIAIIVCYLQSVRVELPIRSTRARGTNNVYPIKLLYTGCLSVLFSYTILFYIHIFAFVLIQLVAKNEPTHIICKIMGHYENANNLLAVPTFPLSLLAPPTSFFKGVTQQPLTFITYSAFILVTGIWFADKWQAISGSSARDVALEFKDQGITLMGRREQNVAKELNKVIPIAAVTGASVLSLITVIGESLGLKGKAAGIVVGIAGGFSLLEVITIEYQQSGGQSALNQVLGVPGAM-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.:::.**: .***: * .*: : :*:::* .: : :* : * :.: **:*::* ::..: **:*:*: * ::*.:*:*:* * ::::: . .** **: *: .:: : : : :::* :* .::. *: :**. *.::. ** *::.**:*:.** :: :. *. :. :*. : :: *.. * :**:* ::: * : .. .: .** * ***: : .: : .* *:*..* :***:*:: ** . *****:**. .:::. :: :.::: :* . * :: . . . *. * : . :*: : * .*:* : *:..* :**:*.:*:* ::*:* :.: *:** .: :**:: ** **. *. :. ::* .: ** *..:.*::. : : * . * . * .. : ", "identical_positions": 110, "similar_positions": 189, "identity": "22.31%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020419-13", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AM26-1", "uniprot_id": "A0A8I6AM26_RAT", "id": "A0A8I6AM26-1", "name": "Serrate RNA effector molecule homolog", "aln": "MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRG-------DDWNDR------EWDRGRERRSRGEYRDYDR-NRRERFSPPRHELSPPQKRMRRDWDEHSS--DPYHSGYDMPYAGGGGGPTYGPPQPWGHPDVHIMQ-HHVLPIQARLGSIAEIDLGVPPPIMKSFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLKVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTEHDLRILEQ---EEEEEQAGKTGETSKKEEGRAGPAPGD--GERKVNDKDEKKEDGKQAENDSSNDDKTKKPEGDGDKEEKKEEAE--KEAKKS-KKRNRKHSGDDSFDEGSVSESESESESG--------------------QAEEEKEEAEEALKEKEKP----KEE-EREKPKD-------------------------------------TAGLEC---------------------KPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASEPGTPP--------------APTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGPPPEEPPKEGNPAEINVERDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRVSHGEVLEWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQ-ILPPGLTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFRGQG-YPGKPRN-RMVRGDPRAIVEYRDLDAPDDVDFF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MR6-1", "uniprot_id": "SRRT_MOUSE", "id": "Q99MR6-1", "name": "Serrate RNA effector molecule homolog", "aln": "MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRG-------DDWNDR------EWDRGRERRSRGEYRDYDR-NRRERFSPPRHELSPPQKRMRRDWDEHSS--DPYHSGYDMPYAGGGGGPTYGPPQPWGHPDVHIMQ-HHVLPIQARLGSIAEIDLGVPPPIMKSFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLKVFLSLMESGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQ---EEEEEQAGKTGEASKKEEARAGPALGE--GERKANDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEEAE--KEAKKS-KKRNRKQSGDDSFDEGSVSESESESEGG--------------------QAEEEKEEAEEALKEKEKP----KEE-EKEKPKD-------------------------------------AAGLEC---------------------KPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASEPGTPP--------------VPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGPPPEEPPKEGNPAEINVERDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVLEWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQ-ILPPGLTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFRGQGGYPGKPRN-RMVRGDPRAIVEYRDLDAPDDVDFF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXP5-1", "uniprot_id": "SRRT_HUMAN", "id": "Q9BXP5-1", "name": "Serrate RNA effector molecule homolog", "aln": "MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRG-------DDWNDR------EWDRGRERRSRGEYRDYDR-NRRERFSPPRHELSPPQKRMRRDWDEHSS--DPYHSGYEMPYAGGGGGPTYGPPQPWGHPDVHIMQ-HHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQ---EEEEEQAGKPGEPSKKEEGRAGAGLGD--GERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSE--KEAKKSSKKRNRKHSGDDSFDEGSVSESESESESG--------------------QAEEEKEEAEEALKEKEKP----KEE-EWEKPKD-------------------------------------AAGLEC---------------------KPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASEPGTPP--------------LPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVERDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVLEWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQ-ILPPGLTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFRGQGGYPGKPRN-RMVRGDPRAIVEYRDLDAPDDVDFF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66I22-1", "uniprot_id": "SRRT_DANRE", "id": "Q66I22-1", "name": "Serrate RNA effector molecule homolog", "aln": "MGDSDDEYDRRRRDKFRRERSDYDRSREREDRRR--------DDWNDRRPSAR-EWDRGRERRSRGEYRDYDR-GRRERFSPPRHDMSPQQKRMRRDWDDHGG--DPYHGGYDLGYGGGGG-PSYAPPQPWGHPDMHLMQPHHGIPIQARLGNIHDMDLGPPPPVMKTFKEFLISLDDSVDETESVKRYNEYKIDFRRQQMQDFFLAHKDEEWFRSKYHPDEAGRRKAEAHSALQNRLGVYMYLMDNNWFESVSLDIERAPQITKILDAAVIKMEGGAENDLRILEQPSEEEEERERLSSGGTPSEPSKRDEPKPAD--TENKPSEEKDKMEEGEESAEKDGEKASAGGSEGE-EKTEKEAPAEPIPEPKKLSKKRKRKHSGD-SEDEASASESESDSDSDSNSHCSEKPSEREREPEEVEEKEEEEEEEGEAADGKEQT----DEQTEREKEKEKK----------------------------------VKDDQPP---------------------RPRPLHRTCSLFMRSIAPTISKAEIVALCRRYPGFMRVCLSEPQPERRFFRRCWVTFDRGVNIKEICWNLQNIRLRDCELAPGVNRDLARRVRNVNGITQHKQVLRNDIKLAAKLIHALDDREKLWSQKPREET--------------PTLELPAQNPILKNITDYLIEEVSAEEEELLGSAGGGDSEDGSKEGNPTEITVERDEKLVKVLDRLLFYLRIVHSIDYYNTCEYPSEDEMPNRCGIIHVRGPIPPNRITLREVSDWQKTFEEKMGPLFSVKENLSEDEAAKMGRKDPEQEVEKFVVANTQELGKDKWLCPLSGKKFKGPEFVRKHILNKHGDKIEEVKKEVVFFNNFLMDAKRPCIPEMKPPPHPGPGQGVLSPG---GLPFPPQGPQGLMGFGQPRPPLMGYG----------GGPPYPPNQYGGGRGNYDNFRGQGGYPGKPRNSRVMRGDPRNIIEYRDLDAPDDVDFF-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V9K7-1", "uniprot_id": "SRRT_DROME", "id": "Q9V9K7-1", "name": "Serrate RNA effector molecule homolog", "aln": "MGDSDDEYDRKRRDKFRGERESY-RTERRDDRRPVGGSAGARDEWAERNPFRGGASAGGGGARHRPDYSDYRGPGARPRYGSPVRDLPP-AKRMRPDWGDGDVRANPRFGGYDPYLMQAWNDHYQSMHSAYSHG-------GHAPPVRESIGGGGGDTLTQP--AMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRSEEQRGFLQRRTDVFMELLENGTIGSVKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLDEKPKDPVVYERKAEQMQSVKEVEKTINSPKEEMSEADPVSTQRKPVRPVNSDGENWDDDDAENSAPKKELAEDSKDSDSKPEDKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDG--LRAEQKTEAEKDRQEATKAKQGPQSPKLDEDEGNENTEPKGLDSKINTYEEIDNTLKSPEISSNPIKNTDNGDGSKVEEDGEKPSVGKDKVVETETIDLDKVKDGQPRALHRTSSIFLRNLAPSITRSEIEAVCNRFSGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCAKIALNLDEKFRLWAEGPKDDSNSARANESSENGSGSTYGFNSQNPVLQNITDYLIEEASAEEEELLGLTG----ENKDTEGEP----IERDEQLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGP-PPVRVTNNDVQEYIKIYESKLQQFLTKTVPLSDEEIKNLGAKDAETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEH-----PGTSK-------------RPESESARGGGGGYRPPMY---------------PPFSAMPYGFGPPMMGGGRGGRNFPPARRE--LPLEHQRRLIGYHDLDAPANSDMFD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********:****** **..* *:..*::** *:* :* * * * :* ** . * *:..* :::.* **** **.: . :* ..**: . . . ..:.* * *:: :*. * * * .:*:** : *:.:.::* :::*.:** **:***:::**:********:.****:: :* * :. **.* *:: *::.. : .: :* .:* : ::**:.***:***::.**::*:: : : . : : : * . . . * :: .. :. .: . . : *.. :: * *: **:.:*:. : * *:.* ***.*.*: : *::.:* :* . :.. .* * : * . :**.**:*.*:*:*.:**.*:::** ::*.*:.*::**.:::* ***::** *:** *.********.*:* ***:**:.. *****:**** **** ***::*.****.**: **:: :**:. * . . : :***:*:*********.********* :* *: .**:* :****:*:.***:*::*******:**** **** ************.*** ** *:: :* :: * :*.*: ::: **::* ::* **.* ****** :*****.******************:****:*** :*::**:*** :***:* *.*** :** **..: : .. * ***: **:. ** * . ** :* *: : . * :: *:***** : *:* ", "identical_positions": 348, "similar_positions": 250, "identity": "34.8%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020419-17", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35093-1", "uniprot_id": "TIM23_RAT", "id": "O35093-1", "name": "Mitochondrial import inner membrane translocase subunit Tim23", "aln": "---MEGGGGSSNKSTGGLAGFFGAGGAGYSNADLAGVP------LTG-------MNPLSPYLNVDP--RYLVQDTDEFILPTGAN---KTRGRFELAFFTIGGCCMTGAAFGALNGLRLGLKETQSMPWSKPRNVQILNMVTRQGALWANTLGSLALLYSAFGVIIEKTRGAEDDFNTVAAGTMTGMLYKCTGGLRGIARGGLAGLTLTSVYALYNNWEHMKGSLLQQSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTQ8-1", "uniprot_id": "TIM23_MOUSE", "id": "Q9WTQ8-1", "name": "Mitochondrial import inner membrane translocase subunit Tim23", "aln": "---MEGGGRSSNKSTSGLAGFFGAGGAGYSNADLAGVP------LTG-------MNPLSPYLNVDP--RYLVQDTDEFILPTGAN---KTRGRFELAFFTIGGCCMTGAAFGAMNGLRLGLKETQSMAWSKPRNVQILNMVTRQGALWANTLGSLALLYSAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCTGGLRGIARGGLAGLTLTSLYALYNNWVHMKGSLLQQSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14925-1", "uniprot_id": "TIM23_HUMAN", "id": "O14925-1", "name": "Mitochondrial import inner membrane translocase subunit Tim23", "aln": "---MEGGGGSGNKTTGGLAGFFGAGGAGYSHADLAGVP------LTG-------MNPLSPYLNVDP--RYLVQDTDEFILPTGAN---KTRGRFELAFFTIGGCCMTGAAFGAMNGLRLGLKETQNMAWSKPRNVQILNMVTRQGALWANTLGSLALLYSAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCTGGLRGIARGGLTGLTLTSLYALYNNWEHMKGSLLQQSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SRD1-1", "uniprot_id": "TI23B_HUMAN", "id": "Q5SRD1-1", "name": "Mitochondrial import inner membrane translocase subunit Tim23B", "aln": "---MEGGGGSGDKTTGVLAGFFGAGEAGYSHADLAGVP------LTG-------MNPLCPYLNVDP--RYLVQDTDEFILPTGAN---KTWGRFELAFFTIGGCCMTGAAFGAMNGLRLGLKETQNMAWSKPGNVQILNMVTRQGALWANTLGSLALLYSAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCT----------VSEMALDSPFCVL-----LSGS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T2P6-1", "uniprot_id": "TIM23_DANRE", "id": "Q7T2P6-1", "name": "Mitochondrial import inner membrane translocase subunit Tim23", "aln": "---MDNSTPPPGGFKGGLGSIFGGGTPEYSNTELSGVP------LTG-------MSPLSPYLNVDP--RYLIQDTDEFILPTGAN---KTRGRFELAFFTIGGCCITGAAFGTLNGLRMGLSETRDMPWSKPRNVQILNMVTRQGASWANTLGSVALLYSVFGVAIEKARGAEDDLNTVAAGTLTGMVFKSTGGLKGVARGGLIGLAMSGLYALYNNWDHLKGKSPSHY-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32897-1", "uniprot_id": "TIM23_YEAST", "id": "P32897-1", "name": "Mitochondrial import inner membrane translocase subunit TIM23", "aln": "MSWLFGDKTPTDDANAAVGGQDTTKPKELSLKQSLGFEPNINNIISGPGGMHVDTARLHPLAGLDKGVEYLDLEEEQLSSLEGSQGLIPSRGWTDDLCYGTGAVYLLGLGIGGFSGMMQGLQNIPPNSPGKLQLNTVLNHITKRGPFLGNNAGILALSYNIINSTIDALRGKHDTAGSIGAGALTGALFKSSKGLKP------MGYSSAMVAAACAVWCSVKKRLLEK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. . . .. :.. * : *. ::* * * .:* .** : ::: *:: : * : : *. : * .:* :.*: **.: . .* :** :*::*. .*. * :** *. :. *: ** .* .::.**::** ::*.: : . :. ", "identical_positions": 35, "similar_positions": 64, "identity": "15.22%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020419-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZWV7-1", "uniprot_id": "RL35_MOUSE", "id": "Q6ZWV7-1", "name": "Large ribosomal subunit protein uL29", "aln": "MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLTKHEEKLKTKKQQRKERLYPLR----------KYAVKA-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17078-1", "uniprot_id": "RL35_RAT", "id": "P17078-1", "name": "Large ribosomal subunit protein uL29", "aln": "MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLTKHEEKLKTKKQQRKERLYPLR----------KYAVKA-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42766-1", "uniprot_id": "RL35_HUMAN", "id": "P42766-1", "name": "Large ribosomal subunit protein uL29", "aln": "MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLNKHEENLKTKKQQRKERLYPLR----------KYAVKA-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JHJ1-1", "uniprot_id": "RL35_DANRE", "id": "Q8JHJ1-1", "name": "Large ribosomal subunit protein uL29", "aln": "MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAIRRQLTKHEENLMTKKMQRKSRLYSIR----------KFAVKA-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1M6G3-1", "uniprot_id": "F1M6G3_RAT", "id": "F1M6G3-1", "name": "Large ribosomal subunit protein uL29", "aln": "-----GSDLRGKKEEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVNSQTQKENLRKFFKGKKYKPLDLRPKKTGAMRRRLTKHEEKLKTKKQQWKERLYPLRTSTQSRTERMTMTIKCETDGKKKKKKEQI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LHE8-1", "uniprot_id": "A0ABK0LHE8_RAT", "id": "A0ABK0LHE8-1", "name": "Large ribosomal subunit protein uL29", "aln": "MAKIKARDLPSKEKEELLKQLEDLKVELSQLCVSKVTGGAASKLSKTGVIRKCSACVLTVINQTQEESLRKFYKGEKYKPLDLPPKKT--THRWLTKQEEELKTKKQQQKEWLYPLR----------RCAVEA-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W499-1", "uniprot_id": "Q9W499_DROME", "id": "Q9W499-1", "name": "Large ribosomal subunit protein uL29", "aln": "MVKVKCSELRIKDKKELTKQLDELKNELLSLRVAKVTGGAPSKLSKIRVVRKAIARVYIVMHQKQKENLRKVFKNKKYKPLDLRKKKTRAIRKALSPRDANRKTLKEIRKRSVFPQR----------KFAVKA-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX84-1", "uniprot_id": "RL35A_YEAST", "id": "P0CX84-1", "name": "Large ribosomal subunit protein uL29A", "aln": "MAGVKAYELRTKSKEQLASQLVDLKKELAELKVQKLS---RPSLPKIKTVRKSIACVLTVINEQQREAVRQLYKGKKYQPKDLRAKKTRALRRALTKFEASQVTEKQRKKQIAFPQR----------KYAIKA-------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX85-1", "uniprot_id": "RL35B_YEAST", "id": "P0CX85-1", "name": "Large ribosomal subunit protein uL29B", "aln": "MAGVKAYELRTKSKEQLASQLVDLKKELAELKVQKLS---RPSLPKIKTVRKSIACVLTVINEQQREAVRQLYKGKKYQPKDLRAKKTRALRRALTKFEASQVTEKQRKKQIAFPQR----------KYAIKA-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *.:::* .** :** ** .* * *:: ..*.* .:**. * * * : *.* :*:.:*.:**:* ** *** :: *. : . * * * :. * :::. ", "identical_positions": 36, "similar_positions": 36, "identity": "24.66%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020419-20", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0CX56-1", "uniprot_id": "RS18B_YEAST", "id": "P0CX56-1", "name": "Small ribosomal subunit protein uS13B", "aln": "MSLVVQEQGSFQHILRLLNTNVDGNIKIVYALT-------------------------------------------------------TIKG----------------------VGRRYSNLVCK---KADVDLHKRAGELTQEELERIVQIMQNPTHYKIPAWFLNRQNDITD---------------------GKDYHTLANNVESKLR-DDLERLKKIRAHRGIR-----------------HFWG---------------------LRVRG------QHTKTTGRR-RA------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX55-1", "uniprot_id": "RS18A_YEAST", "id": "P0CX55-1", "name": "Small ribosomal subunit protein uS13A", "aln": "MSLVVQEQGSFQHILRLLNTNVDGNIKIVYALT-------------------------------------------------------TIKG----------------------VGRRYSNLVCK---KADVDLHKRAGELTQEELERIVQIMQNPTHYKIPAWFLNRQNDITD---------------------GKDYHTLANNVESKLR-DDLERLKKIRAHRGIR-----------------HFWG---------------------LRVRG------QHTKTTGRR-RA------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P62269-1", "uniprot_id": "RS18_HUMAN", "id": "P62269-1", "name": "Small ribosomal subunit protein uS13", "aln": "MSLVIPEK--FQHILRVLNTNIDGRRKIAFAIT-------------------------------------------------------AIKG----------------------VGRRYAHVVLR---KADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKD---------------------GKYSQVLANGLDNKLR-EDLERLKKIRAHRGLR-----------------HFWG---------------------LRVRG------QHTKTTGRRGRTVGVSKKK-----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62270-1", "uniprot_id": "RS18_MOUSE", "id": "P62270-1", "name": "Small ribosomal subunit protein uS13", "aln": "MSLVIPEK--FQHILRVLNTNIDGRRKIAFAIT-------------------------------------------------------AIKG----------------------VGRRYAHVVLR---KADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKD---------------------GKYSQVLANGLDNKLR-EDLERLKKIRAHRGLR-----------------HFWG---------------------LRVRG------QHTKTTGRRGRTVGVSKKK-----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZM33-1", "uniprot_id": "D3ZM33_RAT", "id": "D3ZM33-1", "name": "Small ribosomal subunit protein uS13", "aln": "MSLVIPEK--FQHILRVLNTNIDGRRKIAFAIT-------------------------------------------------------AIKG----------------------VGRRYAHVVLR---KADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKD---------------------RKYSQVLANGLDNKLR-EDLERLKKIRAHRGLR-----------------HFWG---------------------LRVRG------QHTKTTGRRGRTVGVSKKK-----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F6YVP7-1", "uniprot_id": "F6YVP7_MOUSE", "id": "F6YVP7-1", "name": "Small ribosomal subunit protein uS13", "aln": "MSLVIPEK--FQHILRVLNTNIDGRRKIAFAIT-------------------------------------------------------AIKG----------------------VGRRYAHVVLR---KADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKD---------------------GKYSQVLANGLDNKLR-EDLERLKKIRAHRGLH-----------------HFWG---------------------LRVRG------QHTKTTGRRGQTVGVSKKK-----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2KA79-1", "uniprot_id": "A0A0G2KA79_RAT", "id": "A0A0G2KA79-1", "name": "Small ribosomal subunit protein uS13", "aln": "MSLVIPEK--FQHILRVLNTNIDGRWKIAFAIT-------------------------------------------------------AIKG----------------------VGRRYAHVVLR---KADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLDRQKDVKD---------------------GKYSQVLAKGLDNKLH-EDLERLKKIRAHRGLR-----------------HFWD---------------------LRVGG------QHSKTTGRRGHTVGVSKKK-----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JGS9-1", "uniprot_id": "RS18_DANRE", "id": "Q8JGS9-1", "name": "Small ribosomal subunit protein uS13", "aln": "MSLVIPEK--FQHILRVLNTNIDGRRKIAFAIT-------------------------------------------------------AIKG----------------------VGRRYAHVVLR---KADIDLNKRAGELTEDEVERVVTIMQNPRQYKIPDWFLNRQKDIKD---------------------GKYSQVLANGLDNKLR-EDLERLKKIRAHRGLR-----------------HFWG---------------------LRVRG------QHTKTTGRRGRTVGVSKKK-----------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZAU6-1", "uniprot_id": "D3ZAU6_RAT", "id": "D3ZAU6-1", "name": "Small ribosomal subunit protein uS13", "aln": "MSLVVPKK--FQHSLRVLDTNVDGQRKIALAIT-------------------------------------------------------AIKG----------------------VGWRYAHVVLR---KADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDMKD---------------------GKYSQVLANSLDNKLR-EDLERVKKIRAHRGLR-----------------HFWG---------------------LRVRG------RHTKTTGRRGRTVGVSKKK-----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41094-1", "uniprot_id": "RS18_DROME", "id": "P41094-1", "name": "Small ribosomal subunit protein uS13", "aln": "MSLVIPEK--FQHILRIMNTNIDGKRKVGIAMT-------------------------------------------------------AIKG----------------------VGRRYSNIVLK---KADVDLTKRAGECTEEEVDKVVTIISNPLQYKVPNWFLNRQKDIID---------------------GKYWQLTSSNLDSKLR-DDLERLKKIRSHRGLR-----------------HYWG---------------------LRVRG------QHTKTTGRRGRTVGVSKKK-----------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O88178-1", "uniprot_id": "B3GT4_RAT", "id": "O88178-1", "name": "Beta-1,3-galactosyltransferase 4", "aln": "MPLSLFRRLLLAVLLLVIIWTLFGPSGLGEELLSLSLASLLPAPASPGPPLALPRLLIPNPQACGGSGPPPFLLILVCTAPEHLNQRNAIRGSWGAIREARGFRVQTLFLLGEPMGQQFADLASESAAQGDVLQASFQDSYRNLTLKTLTGLNWVNKYCPMARYILKTDDDVYVNVPELVSELIQRGGPSEQWQKGKEPQEETTAVHKEHKGQAVPLLYLGRVHWRVRPTRTPESRHHVSEELWPENWGPFPPYASGTGYVLSISAVQLILKVASRAPYLPLEDVFVGVSARRVGLAPTHCVKLAGATHYPLDRCCYGKFLLTSHKVDPWKMQEAWKLVRGLNGRRTEPFCSWLQGFLGTLRCRFIAWLNS", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.* : .: : * :: .: * : : :*:* :* :::.:. . :.*: . .. : :. : : :. ::*. :.*: * : :. :..: : : : : * * :: . *. *:* . . .* : ", "identical_positions": 17, "similar_positions": 60, "identity": "4.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020419-21", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NTJ3-1", "uniprot_id": "SMC4_HUMAN", "id": "Q9NTJ3-1", "name": "Structural maintenance of chromosomes protein 4", "aln": "MPRKGTQPSTARRREEGPPPPSPDGASSDAEPEPPSGRTESPATAAETASEELDNRSLEEILNSIPPPPPPAMTNEAGAPRLMITHIVNQNFKSYAGEKILGPFHKRFSCIIGPNGSGKSNVIDSMLFVFGYRAQKIRSKKLSVLIHNSDEHKDIQSCTVEVHFQKIIDKEGDDYEVIPNSNFYVSRTACRDNTSVYHISGKKKTFKDVGNLLRSHGIDLDHNRFLILQGEVEQIAMMKPKGQTEHDEGMLEYLEDIIGCGRLNEPIKVLCRRVEILNEHRGEKLNRVKMVEKEKDALEGEKNIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEMETQKEKIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKESREKELMGFSKSVNEARSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAASETLKERKAAIRDIEGKLPQTEQELKEKEKELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVLDAIIQEKKSGRIPGIYGRLGDLGAIDEKYDVAISSCCHALDYIVVDSIDIAQECVNFLKRQNIGVATFIGLDKMAVWAKKMTEIQTPENTPRLFDLVKVKDEKIRQAFYFALRDTLVADNLDQATRVAYQKDRRWRVVTLQGQIIEQSGTMTGGGSKVMKGRMGSSLVIEISEEEVNKMESQLQNDSKKAMQIQEQKVQLEERVVKLRHSEREMRNTLEKFTASIQRLIEQEEYLNVQVKELEANVLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNHKLKAQQDKLDKINKQLDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTAELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQIDGHIAEHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPEDLEAIKNPDSITNQIALLEARCHEMKPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRKQRLNEFMAGFYIITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISDRLIGIYKTYNITKSVAVNPKEIASKGLC--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CG47-1", "uniprot_id": "SMC4_MOUSE", "id": "Q8CG47-1", "name": "Structural maintenance of chromosomes protein 4", "aln": "MRRKGTKPSTACHQEEGPPP-SQDGAHSDEEMEQPAGEAES-AAPAKPPGEELDNRSLEEILNSIPPPPPPAMASEAGAPRLMITHIVNQNFKSYAGEKVLGPFHKRFSCIIGPNGSGKSNVIDSMLFVFGYRAQKIRSKKLSVLIHNSDEHKDIQSCTVEVHFQKIIDKEGDDYEVLPNSNFYVSRTAYRDSTSVYHISGKKKTFKDVGNLLRSHGIDLDHNRFLILQGEVEQIAMMKPKGQTEHDEGMLEYLEDIIGCGRLNEPIKVLCRRVEILNEHRGEKLNRVKMVEKEKDALEGEKNIAIEFLTLENEMFKKKNHICQYYIYDLQNRIAEITTQKEKIHEDTKEITEKSNVLSNEMKAKNSAVKDVEKKLNKVTKFIEQNKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQKDKEKVEELKSVPAKSKTVINETTTRNNSLEKEREKEEKKLKEVMDSLKQETQGLQKEKEIQEKELMGFNKSVNEARSKMEVAQSELDIYLSRHNTAVSQLSKAKEALITASETLKERKAAIKDINTKLPQTQQELKEKEKELQKLTQEEINLKSLVHDLFQKVEEAKSSLAMNRSRGKVLDAIIQEKKSGRIPGIYGRLGDLGAIDEKYDIAISSCCHALDYIVVDSIDTAQECVNFLKKHNIGIATFIGLDKMTVWAKKMSKIQTPENTPRLFDLVKVKNEEIRQAFYFALRDTLVANNLDQATRVAYQRDRRWRVVTLQGQIIEQSGTMSGGGSKVMRGRMGSSVIDEISVEEVNKMESQLERHSKQAMQIQEQKVQHEEAVVKLRHSERDMRNTLEKFAASIQGLSEQEEYLCVQIKELEANVLTTAPDRKQQKLLEENVSVFKKEYDAVAEKAGKVEAEIKRLHNTIIDINNRKLKAQQNKLDTINKQLDECASAITKAQVAIKTADRNLKKAQDSVCRTEKEIKDTEKEINDLKTELKNIEDKAEEVINNTKTAETSLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQIDGHISEHNSKIKYWQKEISKIKLHPVEDNPVETVAVLSQEELEAIKNPESITNEIALLEAQCREMKPNLGAIAEYKKKEDLYLQRVAELDKITSERDNFRQAYEDLRKQRLNEFMAGFYVITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISDRLIGIYKTYNSTKSVAVNPKQIASKGLC--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FGC2-1", "uniprot_id": "E7FGC2_DANRE", "id": "E7FGC2-1", "name": "Structural maintenance of chromosomes protein", "aln": "MPVKTSKTAGRRAAEDSDEEVSKPRKAPSTAVQSSPPPALN-DGAAGESAEVVDSRSLEEILGSIPPAPPPAMSSEPGAPRLMITHIVNRNFKSYAGEQILGPFHKRFSCIIGPNGSGKSNVIDSMLFVFGYRAQKIRSKKLSVLIHSSDGHPDIQSCTVEVHFQKIIDKEGDDYDVIPDSSFYVARTAGKDNSSAYYINTKKATFKDVGTLLRSHGIDLDHNRFLILQGEVEQIAMMKPKGQTEHDEGMLEYLEDIIGSCRLKEPINILCRRVEALNEQRGEKLNRVKMVEKEKSALEGEKNKAVDFLSLENDIFKKRNLLCHFYVHDLQSRVSVKEAEKQQIQEDTKDLSDKSSQLTEEMKSKNEDLKAVEKKLTKLTKYIESQKEKFTQLDLQDVEVREKLKHTKSKTKKLQKQLQKDQEKLEEVRGVPASSEKIITEASAQKEELEKKKLLEEQKLAEVMESLKEETKGLQEDKEKKEKELLELSKSVNETRSRMDVAQSELDIYLSQHNTAINQLNQAKSALQETVDTLRERRAAIKDLQVKIPAQEEQLKKDERELEQISEQDKQTRAQVGDMRQKVAEAKSSLSSNRSRSKVLDTLMQQKRSGKIPGILGRLGDLGAIDEKYDVAISSSCGSLDNILVDTIDTAQKCVTFLKAQNIGVATFIGLDKMKVWQQSMGSISTPENIPRLFDMVRVKDESVRPAFYFALRDTLVAKDLEQATRVAFQKDKRWRVVTLQGQIIEQAGTMTGGGGRVMKGRMGSSVCADVTQEQLDKMESALNKEVTQLQDCQKRKNQLEEKVHKARCELRDMKNTLEKYTATIQSLTEQELHLKPQIKDLEANVIAAAPDKAKQKQMEKSLEAYRKDFEAASNKAGKVEAEVKRLHTLIVDINSHKLKAQQDKLDQINTQLDQCSSAVTKAQVAIKTAGRNLKKSEDGVSRLEQEISENEKLMEELTEQLKKLEEQAGEIMQSYQQAEEALPEVQDQHRAVVQEIKALQEQEHALQKESLSVRLKVEHIDTAITECHNKIKHWQKEASKLCLHHIDGVPAEELPALNPDQLQDIGNPDVIKNEIALLEDRCANMKPNLGAIAEFKKKEELYLQRVAELDDITTQRDSFKRGCEDLRKQRLHEFMAGFNIITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIYNLSGGEKTLSSLALVFALHHFKPTPLYFMDEIDAALDFKNVSIVACYIYEQTKNAQFIIISLRNNMFEMADRLIGIYKTHNTTKNVAINPKTIILREIQTA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * ::.: *:. * .. : .. : . .* ..* :*.*******.****.*****:.*.************:********::***********************************************.** * **********************:*:*:*.***:*** :*.:*.*:*. ** ******.************************************************. **:***::****** ***:***************.******* *::**:***::*:*:* :*::*:::**.*:: ::*::*:****::.:**. *::***:**. :* .****.*:**:**.:*********:**:*******:.**:***:******:**:**.:.:**.*:.:*.*:::::: ***:: **:** ***:***:**:***::** :****: :.*****:**:*:***********:****:.**.:**.** : :**:**:***:*:: *:* :::**:.*:**::::::: : :: * *: *** ******: ****.****:::*:*:**:**** **************:****.* :** *:**:** **:**.*** :***:********* ** :.* .*.**** *****:*:**:*.:* ************.:*:******:*:*:**************:***:***.:**:******: ::: *:::**** *:.. .: : *::* * ** * * * . *:*:*****::*:** * *** :* *:*:*****:::***: :** :*:.:..::.:::*.::********:****. *::**.:******:*** **.***:*:**:**********.***:*::*.* * *:**.:.** :::*. :**.:*::* *:::. : ** :***:*.:** ::**:*.:**:******::**::**:*:** *:* :.***:*:** **: ** ::. * * :..*. ::*: * **: *.*:***** :* :**********:****:**********.** :**.*::. ********:****** :***********************************************:********************:************************ **********************::*********:* **.**:*** * : : ", "identical_positions": 834, "similar_positions": 322, "identity": "64.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020419-22", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYL5-1", "uniprot_id": "SF3B4_RAT", "id": "Q6AYL5-1", "name": "Splicing factor 3B subunit 4", "aln": "MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIMN-MIKLYGKPIRVNKASAHNKNLDVG-----------ANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKG-ERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAGGHGPPAAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGY-TGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRGPLPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8QZY9-1", "uniprot_id": "SF3B4_MOUSE", "id": "Q8QZY9-1", "name": "Splicing factor 3B subunit 4", "aln": "MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIMN-MIKLYGKPIRVNKASAHNKNLDVG-----------ANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKG-ERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAGGHGPPAAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGY-TGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRGPLPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15427-1", "uniprot_id": "SF3B4_HUMAN", "id": "Q15427-1", "name": "Splicing factor 3B subunit 4", "aln": "MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIMN-MIKLYGKPIRVNKASAHNKNLDVG-----------ANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKG-ERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGY-TGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRGPLPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NWB3-1", "uniprot_id": "Q6NWB3_DANRE", "id": "Q6NWB3-1", "name": "Splicing factor 3B subunit 4", "aln": "MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIMN-MIKLYGKPIRVNKASAHNKNLDVG-----------ANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKG-ERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSMPTPVMTALGAAMPIPGMPPPGAFPP-VPPPGTMPPGMPPGMP---MPPAPGTPAPQGGGGPPPGHP--------PFPPAGMHPPGMPHMPMPPTGPPGMVPPPPGPPGSN-QPRAPPPPQMP---PPPMGVPPRGP-FGPPMGPP--MHP-GMRGPPPPMPPPGYGAGPPRPPPFGFQRGPPMPPRPP-----APRGPMRAPAPS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W424-1", "uniprot_id": "Q9W424_DROME", "id": "Q9W424-1", "name": "Splicing factor 3B subunit 4", "aln": "MAAGPIAERNQDATIYAGGLDDKVSETLLWELFVQAGPVVNVHMPKDRVTQMHQGYGFVEFLSEEDADYGIKIMN-MIKLYGKPIRVNKASAHQKNLDVG-----------ANIFIGNLDVEVDEKLLYDTFSAFGVILQTPKIMRDPETGKSKSFAFINFASFEASDAAMDAMNGQYLCNRPISVSYAFKKDHKG-ERHGSAAERLLAAQNPSTHADRPHQLFADAPVQTMMP-QMPGQIPAQMPGQMMPPPMMAPP--------PPVVPVSNN------NMGMLAPP--------------------PPVPQPAP------FPATIP-----PPPLPPMTGGQPPLPPAMGIP---PPPR------------MMQPNAWAPPGMPAPPPRPPPTNW-----RPPPVPFP--PTPYARPY-----QPDGYQY-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99181-1", "uniprot_id": "HSH49_YEAST", "id": "Q99181-1", "name": "Protein HSH49", "aln": "----MNYSADSGNTVYVGNIDPRITKEQLYELFIQINPVLRIKYPKDKVLQAYQGYAFIEFYNQGDAQYAIKIMNNTVRLYDRLIKVRQVTNSTGTTNLPSNISKDMILPIAKLFIKNLADSIDSDQLVKIFNKFGKLIREPEIFYLSNG--KLKCAYVYFEDFEKADLAIKSLNNQLVANNRITVDYAFKENGKGNAKYGDDVDRLLNKEALKHNMLK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.. *:*.*.:* :::: *:***:* .**:. : ***:* :***.*:** .: **:*.***** ::**.: *:*.:.: . :: *::** ** .:*.. * . *. ** ::: *:*: .: . *:: * .*: :* *:.::*.* :.*. *:*.****:: ** ::*. .:*** : : : ", "identical_positions": 65, "similar_positions": 79, "identity": "14.84%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020419-23", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63081-1", "uniprot_id": "VATL_RAT", "id": "P63081-1", "name": "V-type proton ATPase 16 kDa proteolipid subunit c", "aln": "-------------------------------MA--DIKNNPEYSSFFGVMGASSAMVFSAMGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANSLTD--GITLYRSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63082-1", "uniprot_id": "VATL_MOUSE", "id": "P63082-1", "name": "V-type proton ATPase 16 kDa proteolipid subunit c", "aln": "-------------------------------MA--DIKNNPEYSSFFGVMGASSAMVFSAMGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANSLTD--GITLYRSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27449-1", "uniprot_id": "VATL_HUMAN", "id": "P27449-1", "name": "V-type proton ATPase 16 kDa proteolipid subunit c", "aln": "-------------------------------MS--ESKSGPEYASFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEQIMKSIIPVVMAGIIAIYGLVVAVLIANSLND--DISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QSP4-1", "uniprot_id": "F1QSP4_DANRE", "id": "F1QSP4-1", "name": "V-type proton ATPase proteolipid subunit", "aln": "--------------------------------M--DTQN-PQYSPFFAVMGASSAMVFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANNIGD--KISLYKSFLHLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTKG------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P23380-1", "uniprot_id": "VATL_DROME", "id": "P23380-1", "name": "V-type proton ATPase 16 kDa proteolipid subunit c", "aln": "-------------------------------MSSEVSSDNPIYGPFFGVMGAASAIIFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAGALEEPSKYSLYRGFIHLGAGLAVGFSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVAIYLYTK-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQG3-1", "uniprot_id": "Q8IQG3_DROME", "id": "Q8IQG3-1", "name": "V-type proton ATPase proteolipid subunit", "aln": "------------------------------MATDAADKDKPAYSFFFGSMGAASAIIFSALGAAYGTAKSGTGIAAMAVMRPELIMKSIIPVVMAGIIAIYGLVVSVLIAGSLS--DSYTIRKGYIHLAAGLSVGFAGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVAIYLYTK-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTI6-1", "uniprot_id": "Q9VTI6_DROME", "id": "Q9VTI6-1", "name": "V-type proton ATPase proteolipid subunit", "aln": "------------------------------MVTAALNEE-PSYAFFLGCTGAAVAIIFTTLGASYGTAVSGVGIAKMAVNRPDMIMKAIIPVVMAGIIAIYGLVVSVLIAGSIG--DDYTMEDSYVHLGAGLSVGLPGLTAGVAIGIAGDAGVRGTAEQPRLFVGMVLILIFAEVLALYGLIVAIYLYTKL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKQ8-1", "uniprot_id": "Q9VKQ8_DROME", "id": "Q9VKQ8-1", "name": "V-type proton ATPase proteolipid subunit", "aln": "MEMDYYLPVYNGSNSVDVPGLIESLKLKETSISPIVLDRYPPYSPFYGVMGVVFSSVLTSAGAAYGTAVSGTGIAATAVMRPELVMKSIIPVVMAGIIAIYGLVVSVLLSGELAPAPKYSLPTGYVHLAAGLSVGFAGLAAGYAVGEVGEVGVRHIALQPRLFIGMILILIFAEVLGLYGLIIGIYLYTVNIK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25515-1", "uniprot_id": "VATL1_YEAST", "id": "P25515-1", "name": "V-type proton ATPase subunit c", "aln": "-----------------------------------MTELCPVYAPFFGAIGCASAIIFTSLGAAYGTAKSGVGICATCVLRPDLLFKNIVPVIMAGIIAIYGLVVSVLVCYSLGQ--KQALYTGFIQLGAGLSVGLSGLAAGFAIGIVGDAGVRGSSQQPRLFVGMILILIFAEVLGLYGLIVALLLNSRATQDVVC", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A1ZAL7-1", "uniprot_id": "A1ZAL7_DROME", "id": "A1ZAL7-1", "name": "V-type proton ATPase proteolipid subunit", "aln": "---------------------------------MELSLDEPQCASFFCILGAVCAIVFSTLGAAYGTAKASVGISSMSIKHPQLIMKAIVPVVMAGIIAIYGLVIAVLLAGSLSS--PYSAYKGFLNLSAGLAVGVSGMGAGIAIGVVGEAGVRASAQQPKLFVAIILILIFAEVLGLYGLIVAIYLFSK-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32842-1", "uniprot_id": "VATL2_YEAST", "id": "P32842-1", "name": "V-type proton ATPase subunit c'", "aln": "-----------------------------MSTQLASNIYAPLYAPFFGFAGCAAAMVLSCLGAAIGTAKSGIGIAGIGTFKPELIMKSLIPVVMSGILAIYGLVVAVLIAGNLSPTEDYTLFNGFMHLSCGLCVGFACLSSGYAIGMVGDVGVRKYMHQPRLFVGIVLILIFSEVLGLYGMIVALILNTRGSE----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * * : ::: **: *** :. **. :*: ::* ::**:*:**:******::**:. : : .:::*..**.**.. : :* *:* .*:.*** **:**:.::*****:***.***:*:.: * : ", "identical_positions": 54, "similar_positions": 51, "identity": "27.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020419-24", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49736-1", "uniprot_id": "MCM2_HUMAN", "id": "P49736-1", "name": "DNA replication licensing factor MCM2", "aln": "MAESSESFTMASSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARK-RRQVERATEDG---EEDEEMIESIENLEDLKGHSVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPGSCPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTANGFPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMPNTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFIDTQKFSVMRSMRKTFARYLSFRRDNNELLLFILKQLVAEQVTYQRNRFGAQQDTIEVPEKDLVDKARQINIHNLSAFYDSELFRMNKFSHDLKRKMILQQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IF65-1", "uniprot_id": "A0A0R4IF65_DANRE", "id": "A0A0R4IF65-1", "name": "DNA replication licensing factor MCM2", "aln": "MADSSESFNMATSPT--------------RGSRRGD-LTSSPGRDLPPFEDESEGLLGDTLPDEEDDDGEELIGDAMERDYRVIPELDRYEAEGLD-EDEDLSELSPSARAEAEAAMRRRDREQGLGMGRIGRGLLYDSEDEDDKRPTKRQRVLAERAAEGGAMEGEDEEMIESIENLEDMKGHTVREWVSMAAPRLEIYHRFKNFLRTHVDEHGHNVFKERISDMCKENKESLLVNYEELASREHVLAYFLPEAPAEMLKIFDEAAKEVVLAMYPKYDRIAHEIHVRIGNLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLGMVKYNCNKCNFILGPFFQSQNQEVKPGSCPECQSLGPFEINMEQTVYQNYQRITIQESPGKVAAGRLPRSKDAILLADLVDMCKPGDEIELTGIYHNNYDGSLNMANGFPVFATVILANHIARKDEGVAVAELTDEDVKAIVALSKDERIGERIFASIGPSIYAHEDIKRGLALALFGGEAKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYVEKVASRAVFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDVLCVVRDTVDPVQDEMLARFVVGSHIKHHPSNKEG-GVAG--LEEVVLPNTFDVPPIPQELLRKYIIYAKERVRPKLNQMDQDKVARIYSDLRKESMATGSIPITVRHIESMIRMAEAHARMHLRDYVLEDDVNMAIRVMLESFIDTQKFSVMRSMRKTFARYLAFRRDNNELLLFILKQLVSEQVSYQRNRYGAQQDTIEIAEKDLVDKARQINIHSLSAFYDSDLFRSNKFSHDVKKKLIVQQF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*****.**:**: *.*** * ********************* * **::********.******.***** ****** :***:.**:.* * ** ***:**** * *:**: *******::**::**::: * .***:*.* **************:***:********.*****:************.*****************:***:****:**:***************:*:****** *************::.*****.:***********************************.***********:**** ***************** ****:***:*:******* *************************** ********************** ***************:*:**: ***.******** *.:****::***:*****.****.****************.*******************************:***:***:******************************************************************************************************************:************************::******* *:*. * .:***:.* *:***:*:**********:************::*********************************:******:***********************************:*****************:***:*****:********:.**************.*******:*** ******:*:*:*:***", "identical_positions": 762, "similar_positions": 92, "identity": "83.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020419-25", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P83731-1", "uniprot_id": "RL24_HUMAN", "id": "P83731-1", "name": "Large ribosomal subunit protein eL24", "aln": "MKVELCSFSGYKIYPGHGRRYARTDGKVFQFLNAKCESAFLSKRNPRQINWTVLYRRKHKKGQSEEIQKKRTRRAVKFQRAITGASLADIMAKRNQKPEVRKAQREQAIRAAKEAKKAKQASKKTAMAAAKAPTKAAP-KQKIVKPVKVSAPRVGGKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P83732-1", "uniprot_id": "RL24_RAT", "id": "P83732-1", "name": "Large ribosomal subunit protein eL24", "aln": "MKVELCSFSGYKIYPGHGRRYARTDGKVFQFLNAKCESAFLSKRNPRQINWTVLYRRKHKKGQSEEIQKKRTRRAVKFQRAITGASLADIMAKRNQKPEVRKAQREQAIRAAKEAKKAKQASKKTAMAAAKAPTKAAP-KQKIVKPVKVSAPRVGGKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BP67-1", "uniprot_id": "RL24_MOUSE", "id": "Q8BP67-1", "name": "Large ribosomal subunit protein eL24", "aln": "MKVELCSFSGYKIYPGHGRRYARTDGKVFQFLNAKCESAFLSKRNPRQINWTVLYRRKHKKGQSEEIQKKRTRRAVKFQRAITGASLADIMAKRNQKPEVRKAQREQAIRAAKEAKKAKQASKKTAMAAAKAPTKAAP-KQKIVKPVKVSAPRVGGKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RBD1-1", "uniprot_id": "M0RBD1_RAT", "id": "M0RBD1-1", "name": "Large ribosomal subunit protein eL24", "aln": "MKVELCSFSGYKIYPGHGRHYARTDRKVFQFLNDKCESAFLSKRNPQQINWTVLYRRKHKKGQLEEIQKKRTSRAVKFQRAITGASVADIMAKKNQKPEVRKAQRKQAIRAAKEAKKAKQAWKKTAMAAAKAPTKADP-KQKILKPMKVSAPRVGGKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JGR4-1", "uniprot_id": "RL24_DANRE", "id": "Q8JGR4-1", "name": "Large ribosomal subunit protein eL24", "aln": "MKVELCSFSGYKIYPGHGRRYARVDGKVFQFLNAKCESAFLSKRNPRQINWTVLYRRKHKKGQSEEVSKKRTRRAVKFQRAITGASLAEILAKRNQKPEVRKAQREQAIRAAKEAKKAKQATKKQTTQSSKAPAKSAQ-KQKIAKPMKVSAPRVGGKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJY6-1", "uniprot_id": "RL24_DROME", "id": "Q9VJY6-1", "name": "Large ribosomal subunit protein eL24", "aln": "MKIGLCAFSGYKIYPGHGKTMVKIDGKSFTFLDKKCERSYLMKRNPRKVTWTVLYRRKHRKGIEEEASKKRTRRTQKFQRAIVGASLAEILAKRNMKPEVRKAQRDQAIKVAKEQKRAVKAAKKAAAPAP--AKKSAP-KQKAAKVTQKAAPRVGGKR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24000-1", "uniprot_id": "RL24B_YEAST", "id": "P24000-1", "name": "Large ribosomal subunit protein eL24B", "aln": "MKVEVDSFSGAKIYPGRGTLFVRGDSKIFRFQNSKSASLFKQRKNPRRIAWTVLFRKHHKKGITEEVAKKRSRKTVKAQRPITGASLDLIKERRSLKPEVRKANREEKLKANKEKKRAEKAARKAEKAKSAGVQGSKVSKQQAKGAFQKVAATSR---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P04449-1", "uniprot_id": "RL24A_YEAST", "id": "P04449-1", "name": "Large ribosomal subunit protein eL24A", "aln": "MKVEIDSFSGAKIYPGRGTLFVRGDSKIFRFQNSKSASLFKQRKNPRRIAWTVLFRKHHKKGITEEVAKKRSRKTVKAQRPITGASLDLIKERRSLKPEVRKANREEKLKANKEKKKAEKAARKAEKAKSAGTQSSKFSKQQAKGAFQKVAATSR---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: : :*** *****:* .: * * * * : *. : ::**::: ****:*::*:** ** ***: :: * **.*.***: * ::. *******:*.: ::. ** *:* :* :* . : **: : *. ", "identical_positions": 56, "similar_positions": 41, "identity": "35.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020419-26", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62241-1", "uniprot_id": "RU1C_MOUSE", "id": "Q62241-1", "name": "U1 small nuclear ribonucleoprotein C", "aln": "MPKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKDYYQ----------------------------------------------------KWMEEQAQSLIDKTTAAFQQGKIPPAPFSAPP------PAGAMIPPP--------PSLPGPPRPGMMPAPHMGGPPMMPMMGPPPPGMMPVGPAPGMRPPMGGHMPMMPGPPMMRPPARPMMVPTRPGMTRPDR------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZCL3-1", "uniprot_id": "RU1C_RAT", "id": "D3ZCL3-1", "name": "U1 small nuclear ribonucleoprotein C", "aln": "MPKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKDYYQ----------------------------------------------------KWMEEQAQSLIDKTTAAFQQGKIPPAPFSAPP------PAGAMIPPP--------PSLPGPPRPGMMPAPHMGGPPMMPMMGPPPPGMMPVGPAPGMRPPMGGHMPMMPGPPMMRPPARPMMVPTRPGMTRPDR------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09234-1", "uniprot_id": "RU1C_HUMAN", "id": "P09234-1", "name": "U1 small nuclear ribonucleoprotein C", "aln": "MPKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKDYYQ----------------------------------------------------KWMEEQAQSLIDKTTAAFQQGKIPPTPFSAPP------PAGAMIPPP--------PSLPGPPRPGMMPAPHMGGPPMMPMMGPPPPGMMPVGPAPGMRPPMGGHMPMMPGPPMMRPPARPMMVPTRPGMTRPDR------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JGS0-1", "uniprot_id": "RU1C_DANRE", "id": "Q8JGS0-1", "name": "U1 small nuclear ribonucleoprotein C", "aln": "MPKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKDYYQ----------------------------------------------------KWMEEQAQSLIDKTTAAFQQGKIPPTPFPGAP------PPGGSLLPH--------PSIGGPPRPGMLPAPPMGGPPMMPMMGPPPHAMMPGGPGPGMRPPMGGPMQMMPGPHMMRPPARPMMPAVRPGMVRPDR------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VE17-1", "uniprot_id": "RU1C_DROME", "id": "Q9VE17-1", "name": "U1 small nuclear ribonucleoprotein C", "aln": "MPKYYCDYCDTYLTHDSPSVRKTHCTGRKHRDNVKFYYQ----------------------------------------------------KWMEEQAQHLIDATTAAFKAGKITNNPFAGGPGGAPPKPAGVSIPP---------PNMGAPPRPGMPGMPYMP-PLMNPMMG-----MRP--------PPIMNPMAMM-GP----PPPLGTIPGVRPGIMNGPK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05900-1", "uniprot_id": "RU1C_YEAST", "id": "Q05900-1", "name": "U1 small nuclear ribonucleoprotein C", "aln": "MTRYYCEYCHSYLTHDTLSVRKSHLVGKNHLRITADYYRNKARDIINKHNHKRRHIGKRGRKERENSSQNETLKVTCLSNKEKRHIMHVKKMNQKELAQTSIDTLKLLYDGSPGYSKVFVDANRFDIGDLVKASKLPQRANEKSAHHSFKQTSRSRDETCESNPFPRLNNPKKLEPPKILSQWSNTIPKTSIFYSVDILQTTIKESKKRMHSDGIRKPSSANGYKRRRYGN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.::**:**.:*****: ****:* *::* . **: :* ** ** . :. . * * .: ..*. * : : . ..: : :: . :*. . : ", "identical_positions": 29, "similar_positions": 36, "identity": "12.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020419-28", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P30520-1", "uniprot_id": "PURA2_HUMAN", "id": "P30520-1", "name": "Adenylosuccinate synthetase isozyme 2", "aln": "MAFAETYP--AASSLPNGDCGRPRAR----------PGGNRVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGLEGWEKRLIISDRAHIVFDFHQAADGIQEQQRQ--EQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSD----FDGFSERFKVLANQYKSIYPTLEIDIEGELQKLKGYMEKIKPMVRDGVYFLYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVLLKYAHMINGFTALALTKLDILDMFTEIKVGVAYK-LDGEIIPHIPANQEVLNKVEVQYKTLPGWNTDISNARAFKELPVNAQNYVRFIEDELQIPVKWIGVGKSRESMIQLF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P7Y0-1", "uniprot_id": "A0A8M1P7Y0_DANRE", "id": "A0A8M1P7Y0-1", "name": "Adenylosuccinate synthetase", "aln": "MAADSTMSNGQETACLNGEPALKRSRDSLDSLRVPREPQNKVTVVLGAQWGDEGKGKVVDLLAMDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGVLNKKATSFIGNGVVIHLPGLFDEAEKNLQKGNGLQGWEERLKISDRAHIVFNFHQAVDGIQEQLRQ--QQAGKNLGTTKKGIGPAYSSKAARNGLRVCDLVSD----FSVFEEKFRVLAGHYQTTYPNLNIDIDAELQQLKNFAERLRPLVTDGVYFMHKALTGPSKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGVPPSHVGRVYGVVKAYTTRVGVGAFPTEQNNEIGDLLQSRGREFGVTTGRRRRCGWLDLVLVRYAHMVNGFSAIALTKLDILDTLPEIKIGTAYT-VDGKPLPSFPANMDVLTKVQVTYETFPGWSCSTEGVRSFDELPTQAQSYIKFIEDFLQVPVKWVGVGKSRESMIKLF--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y0Y2-1", "uniprot_id": "PURA_DROME", "id": "Q9Y0Y2-1", "name": "Adenylosuccinate synthetase", "aln": "MSASATNG----THYEQLHQGRTKMY------------KSKVDVVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCVSVIGNGVVIHLPSLFDEVLKNEAKG--LQHLENRLIISDRAHLVFDFHQHVDGMQEAEK-----GGKSLGTTKKGIGPAYSSKATRNGIRVGELLGD----FNLFSEKFKSIVATHVRLFPSINVDVEAELARYKDYADKVRPYVKDTICFLHTALRN-GKTILVEGANAAMLDIDFGTYPYVTSSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSLVNGYTCICLTKLDILDTLPEIKVAVAYKKPNGEKLDHFPGTIAELGNIEVEYAVLPGWQTSTEEVRNFKELPENAQSYVRLLESELSVPVRWVGVGKGRESIINVH--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P80210-1", "uniprot_id": "PURA_YEAST", "id": "P80210-1", "name": "Adenylosuccinate synthetase", "aln": "----------------------------------------MVNVVLGSQWGDEGKGKLVDLLVGKYDIVARCAGGNNAGHTIVVDGVKYDFHMLPSGLVNPNCQNLLGNGVVIHVPSFFKELETLEAKG--LKNARSRLFVSSRAHLVFDFHQVTDKLRELELSGRSKDGKNIGTTGKGIGPTYSTKASRSGLRVHHLVNDQPGAWEEFVARYKRLLETRRQRYGDFEYDFEAKLAEYKKLREQLKPFVVDSVVFMHNAIEA-KKKILVEGANALMLDIDFGTYPYVTSSNTGIGGVLTGLGIPPRTIDEIYGVVKAYTTRVGEGPFPTEQLNENGEKLQTIGAEFGVTTGRKRRCGWLDLVVLKYSTLINGYTSLNITKLDVLDTFKEIPVGISYS-IQGKKLDLFPEDLNILGKVEVEYKVLPGWDQDITKITKYEDLPENAKKYLKYIEDFVGVPVEWVGTGPARESMLHKEIK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ****:*********:**:*. . ***.** ********:*.:..::***:****::* : .:*******:*.:*.* . ** *: ..** :*.***:**:*** .* ::* **.:*** *****.**:**:*.*:*: .*:.* :. * ::: : : :: *.:.:* . * ::::* * * : *:: *: *.******** :*********:***** :*** ****:** :..: *********** *.***** *: *: **: * *.**** *:*******: :::*: ::**::.: :****:** : ** :. :*. :*: : :* * :::* * .:***. . :.:** :*:.*:: :*. : :**.*:*.* .***::: ", "identical_positions": 193, "similar_positions": 130, "identity": "40.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020419-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O94766-1", "uniprot_id": "B3GA3_HUMAN", "id": "O94766-1", "name": "Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3", "aln": "--MKLKLKNVFLAYFLVSIAGLLYALVQLGQPCDCLPPLRAAAEQLRQKDLRISQLQAELRRPPP--APAQPPEPEALPTIYVVTPTYARLVQKAELVRLSQTLSLVPRLHWLLVEDAEGPTPLVSGLLAASGLLFTHLVVLTPKAQRLREGEPGWVHPRGVEQRNKALDWLRGRGGAVGGEKDPPPPGTQGVVYFADDDNTYSRELFEEMRWTRGVSVWPVGLVGGLRFEGPQVQDGRVVGFHTAWEPSRPFPVDMAGFAVALPLLLDKPNAQFDSTAPRGHLESSLLSHLVDPKDLEPRAANCTRVLVWHTRTEKPKMKQEEQLQRQGRGSDPAIEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F8W289-1", "uniprot_id": "F8W289_DANRE", "id": "F8W289-1", "name": "Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase", "aln": "MRMRLKLKTVFVLYFMVSLFGLLYALMQLGQRCDCR-------DHEQSKDQQISQLKGELQKLQEHIKTSELSKKTDVPRIYVITPTYARLVQKAELTRLSHTFLHVPQLHWIVVEDAPQQTQLVSDFLSASGLTYTHLNKLTPKERKLQEGDPNWLKPRGAEQRNEGLRWLRWMGSTVHG--KEAAALEEAVVYFADDDNTYSLQLFEEMRYTYRVSVWPVGLVGGMKFERPVVEDGKVVRFHTGWRPNRPFPIDMAGFAVSLRLVLTNKEALFDGDAQMGFLESSFLQHLVTMDDLEPKADLCTKVLVWHTRTEKPKMKREEALLKQGMGSDPDVEV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:****.**: **:**: ******:**** *** :: :.** :****:.**:: .:: .: :* ***:*************.***:*: **:***::**** * ***.:*:**** :*** **** ::*:**:*.*::***.****:.* *** *.:* * . ... :.************ :******:* ***********::** * *:**:** ***.*.*.****:*******:* *:* : :* **. * *.****:*.*** .****:* **:**************:** * :** **** :**", "identical_positions": 199, "similar_positions": 74, "identity": "58.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020419-31", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC40-1", "uniprot_id": "NCBP2_RAT", "id": "B1WC40-1", "name": "Nuclear cap-binding protein subunit 2", "aln": "MSGGLLKALRSDSYVELSEYRDQHFRGDNEEQEKLLKK------SCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYREDYDAGRGGYGKLAQKQ----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ49-1", "uniprot_id": "NCBP2_MOUSE", "id": "Q9CQ49-1", "name": "Nuclear cap-binding protein subunit 2", "aln": "MSGGLLKALRSDSYVELSEYRDQHFRGDNEEQEKLLKK------SCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYREDYDAGRGGYGKLAQKQ----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52298-1", "uniprot_id": "NCBP2_HUMAN", "id": "P52298-1", "name": "Nuclear cap-binding protein subunit 2", "aln": "MSGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKK------SCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JGR6-1", "uniprot_id": "NCBP2_DANRE", "id": "Q8JGR6-1", "name": "Nuclear cap-binding protein subunit 2", "aln": "MS-IKLNALFSDSYVDVSQYRDQHFKGNRYEQEKLLKQ------SATLYVGNLSFYTTEEQVHELFAKCGDVKRIIIGLDKIKKTACGFCFVEYYTRADAENAMRFVNGTRLDDRIIRTDWDAGFKEGRQYGRGKSGGQVRDEYRQDYDPARGGYGKMVQKS----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3L6-1", "uniprot_id": "NCBP2_DROME", "id": "Q9V3L6-1", "name": "Nuclear cap-binding protein subunit 2", "aln": "--------MFAS--VELSSYRDQHFKGSRSEQERSLRD------SCTLYVGNLSFYTTEEQIHELFSRCGDVRVIVMGLDKYKKTPCGFCFVEYYVRSEAEAAMRFVNGTRLDDRLIRVDWDAGFVEGRQYGRGKTGGQVRDEYRTDYDAGRGGYGKLLSQKI------------APNTDNR--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A6PVI3-1", "uniprot_id": "NCB2L_HUMAN", "id": "A6PVI3-1", "name": "Nuclear cap-binding protein subunit 2-like", "aln": "MS-KDLKILCKDPALELSCYRDHQFSGRKFQQEKLLKE------SSTLNMGNLSFYTTEEKIHELFSRS-DIRNIFMGLDKIKKTACGFCFVECHNRADAENAMRFLTGTCLDEWIICTDWDVGFREGQQYGRGKSGGQVRDEFREDFHSGRGGFGRQTQI-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08920-1", "uniprot_id": "NCBP2_YEAST", "id": "Q08920-1", "name": "Nuclear cap-binding protein subunit 2", "aln": "MSLEEFDEVKYDHSTKRLDTPSRYLLRKARRNPNGLQELRESMKSSTIYVGNLSFYTSEEQIYELFSKCGTIKRIIMGLDRFKFTPCGFCFIIYSCPDEALNALKYLSDTKLDEKTITIDLDPGFEDGRQFGRGKSGGQVSDELRFDFDASRGGFAIPFAERVGVPHSRFDNSSSQSNTNNYIPPPDAMGTFRPGFDEEREDDNYVPQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . .: : .: . *:. *.*: :*******:**:::***::. :: *.:***: * *.*****: :* *::::..* **: * * * ** :*:*:***::**** ** * *:...***:. ", "identical_positions": 52, "similar_positions": 47, "identity": "25.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020419-32", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q13547-1", "uniprot_id": "HDAC1_HUMAN", "id": "Q13547-1", "name": "Histone deacetylase 1", "aln": "MAQT-QGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEK--EKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O09106-1", "uniprot_id": "HDAC1_MOUSE", "id": "O09106-1", "name": "Histone deacetylase 1", "aln": "MAQT-QGTKRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEEDPDKRISICSSDKRIACEEEFSDSDEEGEGGRKNSSNFKKAKRVKTEDEK--EKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2R8QIW0-1", "uniprot_id": "A0A2R8QIW0_DANRE", "id": "A0A2R8QIW0-1", "name": "Histone deacetylase 1", "aln": "MALSSQGTKKKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNKQQTDIAINWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPIMSKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTIKGHAKCVEYMKSFNLPLLMLGGGGYTIRNVARCWTFETAVALDSTIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNDYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAVQEDSGDE-EDDPDKRISIRAHDKRIACDEEFSDSEDEGQGGRRNAANYKKPKRVKTEEEKDGEEKKGEPTDVKEEEKASEEKMDTKGPKEELKTV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : ***::**************************************************************************************************************.************:**************************************************************************************************************:*******:**********:***********************::******:******************:*******: *********************************:*******************************: *:**** *:******** : ******:******::**:***:*::*:**.******:** *:. * .:*.****:.*** ::** ***:* .", "identical_positions": 431, "similar_positions": 39, "identity": "88.87%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020419-33", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DFJ4-1", "uniprot_id": "B5DFJ4_RAT", "id": "B5DFJ4-1", "name": "Vacuolar protein sorting-associated protein 18 homolog", "aln": "-MASILDEYEDSLSRSAVLQTGCPSVGIPHSGYVNAHLEKEVPIFTKQRIDFTPSE----RITSLVVSCSQLCMSLG---KDTLLRIDLGKASEPNRVELGRKDDA---KVHKMFLDHTGSHLLVALS--------STEVLYMNRNGQ------KARPLARWKGQLVESVGWNKALGSESSTGPILVGTAQG-QIFEAELSASEGGLFGPAPDLYFRPLYVLNEEGGPAPVCSLEAERGPDGRGFVIATTRQRLFQFIGRAVEDAEAQGFSGLFAAYTD--HPPPFREFPGNLGYSELAFYTPKLRSAPRAFAWMMGDGVLYGSLDCGR---------PDSLLSEEKV---WEYPAGIGPG---ANPPLAIVLTQFHFLLLLADRVEAVCTLTGQVVLRDHFLEK-FGPLRH--------MVKDSSTGHLWAYTERAVFRYHVQREARDVWRTYLDMNRFDLAKEYCRERPDCLDTVLAREADFCFRQHRYLESARCYALTQS---YFEEIALKFLEARQEEALAEFLQRKLAGLKPT----------ERTQATLLTTWLTELYLSRLGALQGDPDALNLYRDTRECFRTFLSSPRHKEWLFA----------SRASIHELLASHGDTEHMVYFAVIMQDYERVVTYHCQHEAYEEALAVLARHRDPQLFYKFSPVLIRHIPRQLVDAWIEMGSRLDARQLIPALVNYSQGGDAQQV----------SQAIRYMEFCVNVLGETEQAIHN--YLLSLYARGQPASLLAYLEQAGASPHRVHYDLKYALRLCAEHGHHRACVHVYKVLELYEEAVDLALQ---VDVDLAKQCADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASCP----LLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQELRGRYGTVEPQDKCSTCDFPLLNRPFYLFLCGHMFHADCLLQAVRPGLPTYKQARLEELQRKLGTAPPPTKGSVKAKEAEAGAAAVGP-SREQLKADLDELVAAECVYCGELMIRSIDRPFIDPQHYEEEHLSWL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R307-1", "uniprot_id": "VPS18_MOUSE", "id": "Q8R307-1", "name": "Vacuolar protein sorting-associated protein 18 homolog", "aln": "-MASILDEYEDSLSRSAVLQTGCPSVGIPHSGYVSAHLEKEVPIFTKQRVDFTPSE----RITSLVVSCNQLCMSLG---KDTLLRIDLGKASEPNRVELGRKDDA---KVHKMFLDHTGSHLLVALS--------STEVLYMNRNGQ------KARPLARWKGQLVESVGWNKAMGNESSTGPILVGTAQG-QIFEAELSASEGGLFGPAPDLYFRPLYVLNEEGGPAPVCSLEAERGPDGRGFVIATTRQRLFQFIGRAVEDTEAQGFAGLFAAYTD--HPPPFREFPSNLGYSELAFYTPKLRSAPRAFAWMMGDGVLYGSLDCGR---------PDSLLSEERV---WEYPAGVGPG---ANPPLAIVLTQFHFLLLLADRVEAVCTLTGQVVLRDHFLEK-FGPLRH--------MVKDSSTGHLWAYTERAVFRYHVQREARDVWRTYLDMNRFDLAKEYCRERPDCLDTVLAREADFCFRQHRYLESARCYALTQS---YFEEIALKFLEARQEEALAEFLQRKLAGLKPT----------ERTQATLLTTWLTELYLSRLGALQGDPDALTLYRDTRECFRTFLSSPRHKEWLFA----------SRASIHELLASHGDTEHMVYFAVIMQDYERVVAYHCQHEAYEEALAVLARHRDPQLFYKFSPILIRHIPRQLVDAWIEMGSRLDARQLIPALVNYSQGGEAQQV----------SQAIRYMEFCVNVLGETEQAIHN--YLLSLYARGQPASLLAYLEQAGASPHRVHYDLKYALRLCAEHGHHRACVHVYKVLELYEEAVDLALQ---VDVDLAKQCADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASCP----LLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQELRGRYGTVEPQDKCSTCDFPLLNRPFYLFLCGHMFHADCLLQAVRPGLPAYKQARLEELQRKLGAAPPPTKGSVKAKEAEAGAAAVGP-SREQLKADLDELVAAECVYCGELMIRSIDRPFIDPQRYEEEHLSWL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P253-1", "uniprot_id": "VPS18_HUMAN", "id": "Q9P253-1", "name": "Vacuolar protein sorting-associated protein 18 homolog", "aln": "-MASILDEYENSLSRSAVLQPGCPSVGIPHSGYVNAQLEKEVPIFTKQRIDFTPSE----RITSLVVSSNQLCMSLG---KDTLLRIDLGKANEPNHVELGRKDDA---KVHKMFLDHTGSHLLIALS--------STEVLYVNRNGQ------KVRPLARWKGQLVESVGWNKALGTESSTGPILVGTAQG-HIFEAELSASEGGLFGPAPDLYFRPLYVLNEEGGPAPVCSLEAERGPDGRSFVIATTRQRLFQFIGRAAEGAEAQGFSGLFAAYTD--HPPPFREFPSNLGYSELAFYTPKLRSAPRAFAWMMGDGVLYGALDCGR---------PDSLLSEERV---WEYPEGVGPG---ASPPLAIVLTQFHFLLLLADRVEAVCTLTGQVVLRDHFLEK-FGPLKH--------MVKDSSTGQLWAYTERAVFRYHVQREARDVWRTYLDMNRFDLAKEYCRERPDCLDTVLAREADFCFRQRRYLESARCYALTQS---YFEEIALKFLEARQEEALAEFLQRKLASLKPA----------ERTQATLLTTWLTELYLSRLGALQGDPEALTLYRETKECFRTFLSSPRHKEWLFA----------SRASIHELLASHGDTEHMVYFAVIMQDYERVVAYHCQHEAYEEALAVLARHRDPQLFYKFSPILIRHIPRQLVDAWIEMGSRLDARQLIPALVNYSQGGEVQQV----------SQAIRYMEFCVNVLGETEQAIHN--YLLSLYARGRPDSLLAYLEQAGASPHRVHYDLKYALRLCAEHGHHRACVHVYKVLELYEEAVDLALQ---VDVDLAKQCADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASCP----LLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQELRGRYGTVEPQDKCATCDFPLLNRPFYLFLCGHMFHADCLLQAVRPGLPAYKQARLEELQRKLGAAPPPAKGSARAKEAEGGAATAGP-SREQLKADLDELVAAECVYCGELMIRSIDRPFIDPQRYEEEQLSWL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P59015-1", "uniprot_id": "VPS18_DANRE", "id": "P59015-1", "name": "Vacuolar protein sorting-associated protein 18 homolog", "aln": "-MASILDQYEDSQNIRQHSRMSTANIGITHSGFVNVRLEEEKPIFTKQRIDFSPPE----KINQFSVCNNQLCMSLG---KDTLLRIDLGKPDQPNQIELGRKDDS---KVHRLFLDPTGSHLVICLT--------TNECVYLNRNTQ------KVRGLSRWRGHLIESIGWNKLIGSETNTGPILVGTSQG-IIFEAEISASEGSLFNTNPDQYFRQVHYLEEDGKPAPVCCLEVERGLETKYFIIATTRKRLFQFVGKLAEGSEQQGFSSIFAQNQD--LLPSFQEFPVNMGYSEITFYTSKLRSRPKTFAWMMGNGVLYGQLDYVR---------PDSLLSDVQV---WEYTQDIDLN---FVKPISIVLTQFHFLLLLPDRVRGICTLNGQVVHEDVFPEK-FGTLQK--------MIKDPITGLVWIYTEKAVFRYHIQKEARDVWQMYMNMNKFDLAKEYCKDRPECLDMVLAKEAEHCFQNKRYLESAKCYALTQN---YFEEIALKFIEAKQEEALKEFLIKKLVNLKPS----------EKTQITLLVTWLTELYLNRLGQLEADEGKQHLFLETREEFRTFLKSPKHKDCFYN----------NRSTIYDLLASHGDVDNMVYFSVIMQDYERVISHYCQHDDYSAALDVLSKHCDDKLFYKFSPVLMQHIPKKVVDAWIQMGNRLDPKNLIPALVNYSQMGSMQQI----------NETIRYMEFCVYELDVKEEAIHN--YLLSLYAKHKPDALLWYLEQAGTHVSDIHYDLKYALRLCSEHGYLQACVLVYKIMELYEEAVDLALK---VDVDLAKSCADLPEDDEELRKKLWLKIARHVVQEEKDVKKAMNCLSSCN----LLKIEDILPFFPDFVTIDHFKEAICSSLEEYNKHIEELKQEMEEATESAKRIREDIQEMRNKYGVVESQEKCATCDFPLLNRPFYLFLCGHMFHYDCLLQEVIPHLSVYKQNKLDELQKKLAATTQTTKARHKPREEDTVSLGKGQGSREQIKSDIDDIIACECVYCGELMIKSIDKPFIDPQKFDQEMSSWL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24314-1", "uniprot_id": "VPS18_DROME", "id": "Q24314-1", "name": "Vacuolar protein sorting-associated protein 18 homolog", "aln": "MDTSMPNQPKFLPRIEHNSSGATANSYVATASGNPFETDEEDEIFSRHKMVLRVPSNCTGDLMHLAVSRNWLVCLLGTPERTTLLRFFLPRAIPPGEAVLEKYLSGSGYKITRMFLDPTGHHIIIALVPKSATAGVSPDFLYIHCLESPQAQQLKVRRIEKFKDHEITAVAFNPYHGNESSTGPILLGTSRG-LIFETELNPAADGHVQR------KQLYDLGLGRPKYPITGLKLLRVPNSSRYIIVVTSPECIYTFQETLKAEE-RSLQAIFAGYVSGVQEPHCEERKTDLTFSQLRFFAPPNSKYPKQWAWLCGEGIRVGELSIEAN-------SAATLIGNTLINLDFEKTMHLSYGERRLNTPKAFVLTEYHAVLLYADHVRAICLLNQEQVYQEAFDEARVGKPLS--------IERDELTGSIYVYTVKTVFNLRVTREERNVWRIYLDKGQYELATAHAAEDPEHLQLVLCQRADAAFADGSYQVAADYYAETDK---SFEEVCLKFMVLPDKRPIINYVKKRLSRVTTKPMETDELDEDKMNIIKALVIWLIDLYLIQINMPDKDEE---WRSSWQTEYDEFMMEAHVLSCTRQ----------NRETVRQLIAEHADPRNMAQFAIAIGDYDEVVAQQLKAECYAEALQTLINQRNPELFYKYAPELITRLPKPTVDALMAQGSRLEVEKLVPTLIIME---NREQR----------EQTQRYLEFAIYKLNTTNDAIHN--FLLHLYAEHEPKLLMKYLEIQGRDESLVHYDIYYAHKVCTDLDVKEARVFLECMLRKWISAVDLALT---FDMKLAKETASRP-SDSKIRRKLWLRIAYHDIKGTNDVKKALNLLKECD----LLRIEDLLPFFADFEKIDNFKEAICDALRDYNQRIQELQREMAETTEQTDRVTAELQQLRQHSLTVESQDTCEICEMMLLVKPFFIFICGHKFHSDCLEKHVVPLLTKEQCRRLGTLKQQLEAEVQTQAQPQSGALSKQQAMELQR-KRAALKTEIEDILAADCLFCG-LLISTIDQPFVD--DWEQVNVEWE-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P27801-1", "uniprot_id": "PEP3_YEAST", "id": "P27801-1", "name": "Vacuolar membrane protein PEP3", "aln": "--------------------------------MIKTRIEEVQLQFLTGNT----------ELTHLKVSNDQLIVTTQR----TIYRINLQDPAIVNHFDCPLSKEL--ETIMNVHVSPMGSVILIRTN----------FGRYMLLKDG------EFTQLNKIKNLDLSSLHW-------INETTFLMGIKKTPKLYRVELTG-----------------------KDITTKLWYENKKLSGGIDGIAYWEGSLLLTIKDNILYWRDVTNMKFPLVLPDE-------SEQFERLKHHAIKKFDS----YNGLFAWVTSNGIVFGDLKEKQMEKDPASNNFGKFLSSSKVLLNFELPDYQNDK---DHLIKDIVLTAFHILLLRKNTVTMVSQLNNDVVFHETIPRHQLTGSNTDSNEKFLGLVRDSVKETFWCFSNINVFEIIIENEPNSVWNLLVRDNKFDKALSLKGLTVREIESVKLSKAMYLFHTAKDFHSAAQTLGSMKDLSHFGEIALNFLQIKDYNDLNVILIKQLDNVPWK------------STQVVLSSWIIWNFMKQLNDIELKINTTKPASTDEDNLLNWNLNLKEKSNELTKFLESHLEKLDNETVYQIMSKQNRQNELLIFASLINDMKFLLSFWIDQGNWYESLKILLTINNHDLVYKYSLILLLNSPEATVSTWMKIKD-LDPNKLIPTILKFFTNWQNNSKLITNISEYPENYSLTYLKWCVREVPKMCNPIVYNSILYMMITDPRNDMILENDIIKFMKSNENKYDLNFQLRLSLKFKKTKTSIFLLTRLNLFEDAIDLALKNNLIDDCKVIVNDEILIEDYKLRKRLWLKIAKHLLLSMKDIDIKQLIRTILNDSNEILTIKDLLPFFNEYTTIANLKEELIKFLENHNMKMNEISEDIINSKNLKVEINTEISKFNEIYRILEPGKSCDECGKFLQIKKFIVFPCGHCFHWNCIIRVILNSNDYNLRQKTENFLKAKSKHN---------------------------LNDLENIIVEKCGLCSDININKIDQPISID---ETELAKWNE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: * . : : *. . * *: *: * . .. . .: .:.:. * ::: *: : : : :. : :: : . .:*:* : ::..*:. . : : : : . : .: :. . * : . : : . :**: .:*: * *. .::.. : :* . . :*** :* :** : * :. *. : * .: : . . : :* . .: :: **. : .* ..**. : .::: * :: * .* * :* : . * *:.*:*: : . : : ::* : . * *: :: ::. : . . : . : . .. :: ::::.: .: *: : * . ::: . : :* * : .*.**:: *: . *. *.: : . *: .:*:*::: . :. . : *:::.: : :.* * : : . :: :**: : ::. . .: : : :. : .*:**** .* . . .* ::*::***:** * : :*:. :* *:*:**** :: .* ::** : . *. :* :::*:..:: ::. .: ::.::. :*. ..* * * : * :* *** ** :*: : : : : : ::::::. .* *. : * .**:*: : .* ", "identical_positions": 110, "similar_positions": 285, "identity": "10.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020419-34", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZER4-1", "uniprot_id": "D3ZER4_RAT", "id": "D3ZER4-1", "name": "Denticleless protein homolog", "aln": "MTSVWRGVWRPGLAVAGVGGKTVSRCGGRKRRLRRNLGAISSAFSSAESSPQDEMLFNSVLRQPQLGVLRNGWSSHYPLQSLLSGYRCSCNDEHTSYGETGVPVPPFGCTFCTAPSMEHILAVANEEGFVRLYNTESQTS--KKTCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAG--ELMGTCKGHQCSLKSVAFSKFQKAVFCTGGRDGNIMIWDTRCNKKDGFYRQVNQISGAHNTADKQTPSKPKKKQNSKGLAPSVDSQQSVTVVLFQDENTVVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGTSTRKLGYSSLVLDSTGSTLFANCTDDNIYMFNMTGLKTSPLAVFNGHQNSTFYVKSSLSPDDQFLISGSSDEAAYIWKVSMPWHPPTVLLGHSQEVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLE-EKPEGDKHSIVGWTSQKKKEVKAGPVSAP-------NSLSTPAKAPRSQCSPSASSPSSAR-TPSCAGDLPLP--SNTSTFSVKTTPVTTRSPVSRRGSSSSVSPKPPSSFKMSLRNWVTRTPSSSPPVTPPASETKISSPRKALIPVSQKSSQADACSESRNRVKRRLDSSCLESVKQKCVKSCNCVTELDGQVESLHLD---LCCLSGTQEVLSQDSAGPTKSSKTEGTGTSISEPPSPVSPFASEGCGPLPLPLGPCGEGSEMVGKENSSPEN-------KNWLLAMAAKHKAENSSPRSPSSQTPSSRRQSRKTSPGPVTITPNSMRKICTYFRRKTQDDFCSPEHSTEL---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TLR7-1", "uniprot_id": "DTL_MOUSE", "id": "Q3TLR7-1", "name": "Denticleless protein homolog", "aln": "------------------------------------------------------MLFNSVLRQPQLGVLRNGWSSHYPLQSLLSGYQCNCNDEHTSYGETGVPVPPFGCTFCTAPSMEHILAVANEEGFVRLYNTESQTS--KKTCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVRAG--ELMGTCKGHQCSLKSVAFPKFQKAVFSTGGRDGNIMIWDTRCNKKDGFYRQVNQISGAHNTADKQTPSKPKKKQNSKGLAPAVDSQQSVTVVLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGTSTRKLGYSSLVLDSTGSTLFANCTDDNIYMFNMTGLKTSPVAVFNGHQNSTFYVKSSLSPDDQFLISGSSDEAAYIWKVSMPWHPPTVLLGHSQEVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLE-EKP-GDKHSIVGWTSQKKKEVKACPVTVP-------SSQSTPAKAPRAKSSPSISSPSSAACTPSCAGDLPLP--SSTPTFSVKTTPATTRSSVSRRGSISSVSPKPLSSFKMSLRNWVTRTPSSSPPVTPPASETKISSPRKALIPVSQKSSQADACSESRNRVKRRLDSSCLESVKQKCVKSCNCVTELDGQAESLRLD---LCCLSGTQEVLSQDSEGPTKSSKTEGAGTSISEPPSPVSPYASEGCGPLPLPLRPCGEGSEMVGKENSSPEN-------KNWLLAIAAKRKAENSSPRSPSSQTPSSRRQSGKTSPGPVTITPSSMRKICTYFRRKTQDDFCSPEHSTEL---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZJ0-1", "uniprot_id": "DTL_HUMAN", "id": "Q9NZJ0-1", "name": "Denticleless protein homolog", "aln": "------------------------------------------------------MLFNSVLRQPQLGVLRNGWSSQYPLQSLLTGYQCSGNDEHTSYGETGVPVPPFGCTFSSAPNMEHVLAVANEEGFVRLYNTESQSF--RKKCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAG--ELIGTCKGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWDTRCNKKDGFYRQVNQISGAHNTSDKQTPSKPKKKQNSKGLAPSVDFQQSVTVVLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGSSTRKLGYSSLILDSTGSTLFANCTDDNIYMFNMTGLKTSPVAIFNGHQNSTFYVKSSLSPDDQFLVSGSSDEAAYIWKVSTPWQPPTVLLGHSQEVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLE-EKPGGDKLSTVGWASQKKKESRPGLVTVT-------SSQSTPAKAPRAKCNPSNSSPSSAACAPSCAGDLPLP--SNTPTFSIKTSPAKARSPINRRGSVSSVSPKPPSSFKMSIRNWVTRTPSSSPPITPPASETKIMSPRKALIPVSQKSSQAEACSESRNRVKRRLDSSCLESVKQKCVKSCNCVTELDGQVENLHLD---LCCLAGNQEDLSKDSLGPTKSSKIEGAGTSISEPPSPISPYASESCGTLPLPLRPCGEGSEMVGKENSSPEN-------KNWLLAMAAKRKAENPSPRSPSSQTPNSRRQSGKKLPSPVTITPSSMRKICTYFHRKSQEDFCGPEHSTEL---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RHI5-1", "uniprot_id": "DTL_DANRE", "id": "Q5RHI5-1", "name": "Denticleless protein homolog", "aln": "-----------------------------------------------------MTLFHHVVDRGAKKRGRNGEQRLFPLSSLLDGYECARRDEHISYGASAAAVPPFGCTFSSAHGQQNCLAVANEEGFVTIFNTGEK----QSSVLKEWQAHDNAVFDIAWVPGTNCLVTASGDQTARLWDVITG--DLLGTFKGHQCSLKSVAFYKQEKAVFSTGGRDGNIMIWDTRCSKKDGFYRQVKQISGAHMKPERFTPQTKKRR----GMAPPVDSQQGVTVVLFCDETKLISSGAVDGIIKMWDLRRNYTAYHQNPLPLQAYPYPGSCTRKLGYSGLSLDYTGSRLFSNCTDDNIYMFNISGLKTTPVAVFSGHSNSSFYVKSTVSPDDQFLASGSSDHNVYIWKISDPKQAPMMLQGHSQEVTSVAWCPTDFTKIASCSDDNTVRIWRLNRKPEGENSTIQDGNLVGWTIRKVQSPNRTPGHHS-------PVELTPSKNPGSVRSVSLASPQPATCAPTGA-ALPLP--SNTS----SAPPAKLTS------------PKMPS----SLQQWISRS-SKSP-------------VRKALTPVLQGLS-------FEHRVKRRLETG--DSASSGLGEEIDGVSELYPNVKRSRSS---VSTLK------KEDSFG-LESEKRLGS------------------------------DGAEASGKENSSPRR-------TDWLSVISQKFKG-SAQPKSPSS---GSSQQDTRTLESPAAVSPRPMKVFSPPTNKKASPSKPMKKISSYFMKRTQD---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24371-1", "uniprot_id": "L2DTL_DROME", "id": "Q24371-1", "name": "Protein lethal(2)denticleless", "aln": "-----------------------------------------------------MNIYNKLRAREHGYGNERTYDFALRRLSVAKEDSWRGIAPANYCPDFNPEPPIFSAKFANCDGYRHILAIANEDGKITLQDTTQRNHQPEEQSLVGPQCHFNAVFDLEWAPGQMRFVSASGDHTARLWEVAGSGIRGLNSYVGHTRSVKSAAFKRTDPAVFATGGRDGAILIWDIRANLNMDLTSRVDNCIYSGHTGGPGTPVSQRKQRTRTPKMAGGTTSSSITGLAFQDNDTLISCGAGDGVIKVWDLRRNYTAYKKEPLPRHKLPYAGSSTFRG-FTNLIVDASGTRLYANCMDNTIYCYNLASYSQRPLACYKGLLNSTFYIKSCLSPDGKYLLSGSSDERAYIWNLDHAEEPLVALAGHTVEVTCVAWGSSHDCPIVTCSDDARHKIWRIGPDLDGLSEAERAEKYRGTASYVREFGKKAFGPSSGNHKYNLRDLESTPRSLKRLMDQNERTPGSVEKTTTKRSFLEMLGVAGQETEATEQPQKRAKPLESRGRRLFGPSSQETACRHIQLQSINEEDASPSKRQKENSAAEDVSPLHKLLSTPSHSPLSENVNHVYTSPPTTSAAAAAVAADALNPPPISAAIYSPTSNLPNYVLDGEAPHLGIMSPKRKAKEKVDWLTNIRKQKLMSGRAHVTLSEKISEEQQADVLASPRLQSLRQSECSPRIHASPRRRISHTDGGGGTPAGSSSHSHSQSQPKTPTSSRRNSETTLLRFFSIQRSSSVPAEETTTTNAAPSSSDPHPPAVTAPAATPLSMRTPTTAVGSD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: : : .. . *: * *...*... . .: **:***:* : : :* .: .. : .* *****: *.** :*:*:**:**::*:* . :.: ** *:**.** : : ***.****** *::** *.. : .: :*.: : . ** . ::: . ...:* : * *: .::*.** **:**:****:*****:::*:. : *.*:.* : ::.* :* :*: *::** *:.** :*::. . *:* :.* **:**:** :***.::* *****. .***::. . .. * **: ***.*.* .:. *.:**** :***:. : . . * : : . . :..: . . :* .. :.: * : :. . . . .: : .::. . * * :* * . : . :. : : . : . ::. . . : :* : ::**.. . . : . . ...*::*:* .* : : : . . . .:. :. ", "identical_positions": 135, "similar_positions": 209, "identity": "16.4%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020419-35", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0Z5-1", "uniprot_id": "A0A8I6A0Z5_RAT", "id": "A0A8I6A0Z5-1", "name": "Protein MAK16 homolog", "aln": "NQNDSPTSLIVIWNTLGNKQFCSYKIRT-KTQGFCRNEYSLTGLCNRSSCPLANSQYATIKEEKGQCYLYMKVIERAAFPRRLWERVRLNKNYEKALEQIDENLIYWPRFIRHKCKQRFTKITQYLIRIRKLTLKRR-KKLVPLSKKVERREKRREEKALIAAQLDNAIEKELLERLKQDTYGD-IYNFPIHAFDKALEKQEAESDSED-EEDEE-EDEE----------------EDVGK----REFVE---DDEVEESDLSDFE----DMDKLNTDS-------------EED--DESSREEE----------AHKAKHKGKAPLKGPLR-KKRAYVEIEYEQETEPMAKAKAT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGS0-1", "uniprot_id": "MAK16_MOUSE", "id": "Q8BGS0-1", "name": "Protein MAK16 homolog", "aln": "MQSDD-----VIWNTLGNKQFCSFKIRT-KTQGFCRNEYSLTGLCNRSSCPLANSQYATIKEEKGQCYLYMKVIERAAFPRRLWERVRLSKNYEKALEQIDENLIYWPRFIRHKCKQRFTKITQYLIRIRKLTLKRQ-RKLVPLSKKVERREKRREEKALIAAQLDNAIEKELLERLKQDTYGD-IYNFPIHAFDKALEKQEAESDSED-EEEEEDEDEE----------------EDVGK----REFVE---DEEVEESDLSDFE----DMDKLNTDS-------------EEDQDDESSNDEE----------AHKAKHKGKAPLKGPLR-KKRAYVEIEYEQETEPMAKVKAT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXY0-1", "uniprot_id": "MAK16_HUMAN", "id": "Q9BXY0-1", "name": "Protein MAK16 homolog", "aln": "MQSDD-----VIWDTLGNKQFCSFKIRT-KTQSFCRNEYSLTGLCNRSSCPLANSQYATIKEEKGQCYLYMKVIERAAFPRRLWERVRLSKNYEKALEQIDENLIYWPRFIRHKCKQRFTKITQYLIRIRKLTLKRQ-RKLVPLSKKVERREKRREEKALIAAQLDNAIEKELLERLKQDTYGD-IYNFPIHAFDKALEQQEAESDSSDTEEKDDDDDDE----------------EDVGK----REFVE---DGEVDESDISDFE----DMDKLDASS-------------DEDQDGKSSSEEEEEK-------ALSAKHKGKMPLRGPLQ-RKRAYVEIEYEQETEPVAKAKTT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYD4-1", "uniprot_id": "MAK16_DANRE", "id": "Q6NYD4-1", "name": "Protein MAK16 homolog", "aln": "MQHDD-----VIWDLIGNKSFCSYKVKT-KTQQFCRNEYNITGLCNRSSCPLANSQYATIREEKGQCFLYMKVIERAAFPSRMWEKVKLDRNYAKALEQIDENLIYWPRFIRHKCKQRLTKITQYLIRIRKLTLKRQ-RKLVPLSRKVERREKRREEKALIAAQLENAIEKELLDRLKQGTYGD-IYNFPINAFDKAMEKQDEESESEE----EEEEEDE----------------EESGT----REFIA---EDEFEESDLSDFE----ELNNLKDSS-------------DEEVNDEEESSEESEEESEEEEVKSKAKSKGKAPLKGPSR-KKRAYVEIEYEQETEPAQKSKAT--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3B2-1", "uniprot_id": "Q9W3B2_DROME", "id": "Q9W3B2-1", "name": "Protein MAK16 homolog", "aln": "MQHDD-----VVWSII-NKSFCSHKVKT-DTRTFCRHEYNLTGLCTRRTCPLANSQYATVREEKGIIYLFIKTAERAHMPSKLWERIKLSRNFEKAIEQINENLVFWPKYMIAKNKQRFLKITQYLIRMRRLKLRRQ-KLIVPLSTKIERREARREEKALVAAKIDNHIEKALMDRLKNGTYRD-IYNFSQTAFNKALEAERVDEDDEE-ELDDEDENEEQLEREMEVDGDDSREAEEVQRSLLDEEFVEADTDDEEEDDDDDDDD----DEDDYDSDSGKREEVEVGSDFEESDEDDDADADDIEETKVPAKKTASKAKKDKKSPAGNSRRSRSKPKLQLEYEYEVEKEAQRQMRH-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10962-1", "uniprot_id": "MAK16_YEAST", "id": "P10962-1", "name": "Protein MAK16", "aln": "-MSDE-----IVWQVI-NQSFCSHRIKAPNGQNFCRNEYNVTGLCTRQSCPLANSKYATVKCDNGKLYLYMKTPERAHTPAKLWERIKLSKNYTKALQQIDEHLLHWSKFFRHKCKQRFTKLTQVMITERRLALREEERHYVGVAPKVKRREQNRERKALVAAKIEKAIEKELMDRLKSGAYGDKPLNVDEKVWKKIMGQMEEENSQDE--EEDWDEEEE----------------SDDGE----VEYVAD--DGEGEYVDVDDLEKWLADSDREASSAS------------ESESDSESESDSDS---------DEENKNSAKRRKKGTSAKTKRPKVEIEYEEEHEVQNAEQEVAQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. ::*. : *:.***.:::: . : ***:**.:****.* :******:***:: ::* :*::*. *** * ::**:::*.:*: **::**:*:*:.*.::: * ***: *:** :* *:* *:.. : * :: *::*** .**.***:**:::: *** *::***..:* * *. .:.* : :....: : :::* .: *:: : * : * .* : : : .: :.: .. . .. . * . * .. .:. :::*** * * : ", "identical_positions": 89, "similar_positions": 116, "identity": "24.86%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020419-37", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PQX0-1", "uniprot_id": "UXS1_RAT", "id": "Q5PQX0-1", "name": "UDP-glucuronic acid decarboxylase 1", "aln": "-MVSKGLLRLVSSVNRRKMKLLLGIALFAYAAS---------------VWGNFVN--MRSIQ----ENGELKIES-----KIEEIIEPLREKIRDLEKSFTQKYPPVKFLSEKDRKRILITGGAGFVGSHLTDKLMMDGHEVTVVDNFFTGRKRNVEHWIGHENFELINHDVVEPLYIEVDQIYHLASPASPPNYMYNPIKTLKTNTIGTLNMLGLAKRVGARLLLASTSEVYGDPEVHPQSEDYWGHVNPIGPRACYDEGKRVAETMCYAYMKQEGVEVRVARIFNTFGPRMHMNDGRVVSNFILQALQGEPLTVYGSGSQTRAFQYVSDLVNGLVALMNSNVSSPVNLGNPEEHTILEFAQLIKNLVGSGSEIQFLSEAQDDPQKRKPDIKKAKLMLGWEPVVPLEEGLNKAIHYFRKELEYQANNQYIPKPKPARVKKGRTRHS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XL3-1", "uniprot_id": "UXS1_MOUSE", "id": "Q91XL3-1", "name": "UDP-glucuronic acid decarboxylase 1", "aln": "-MVSKGLLRLVSSVNRRRMKLLLGIALFAYAAS---------------VWGNFVN--MRSIQ----ENGELKIES-----KIEEIVEPLREKIRDLEKSFTQKYPPVKFLSEKDRKRILITGGAGFVGSHLTDKLMMDGHEVTVVDNFFTGRKRNVEHWIGHENFELINHDVVEPLYIEVDQIYHLASPASPPNYMYNPIKTLKTNTIGTLNMLGLAKRVGARLLLASTSEVYGDPEVHPQSEDYWGHVNPIGPRACYDEGKRVAETMCYAYMKQEGVEVRVARIFNTFGPRMHMNDGRVVSNFILQALQGEPLTVYGSGSQTRAFQYVSDLVNGLVALMNSNVSSPVNLGNPEEHTILEFAQLIKNLVGSGSEIQFLSEAQDDPQKRKPDIKKAKLMLGWEPVVPLEEGLNKAIHYFRKELEYQANNQYIPKPKPARVKKGRTRHS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NBZ7-1", "uniprot_id": "UXS1_HUMAN", "id": "Q8NBZ7-1", "name": "UDP-glucuronic acid decarboxylase 1", "aln": "-MVSKALLRLVSAVNRRRMKLLLGIALLAYVAS---------------VWGNFVN--MRSIQ----ENGELKIES-----KIEEMVEPLREKIRDLEKSFTQKYPPVKFLSEKDRKRILITGGAGFVGSHLTDKLMMDGHEVTVVDNFFTGRKRNVEHWIGHENFELINHDVVEPLYIEVDQIYHLASPASPPNYMYNPIKTLKTNTIGTLNMLGLAKRVGARLLLASTSEVYGDPEVHPQSEDYWGHVNPIGPRACYDEGKRVAETMCYAYMKQEGVEVRVARIFNTFGPRMHMNDGRVVSNFILQALQGEPLTVYGSGSQTRAFQYVSDLVNGLVALMNSNVSSPVNLGNPEEHTILEFAQLIKNLVGSGSEIQFLSEAQDDPQKRKPDIKKAKLMLGWEPVVPLEEGLNKAIHYFRKELEYQANNQYIPKPKPARIKKGRTRHS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6GMI9-1", "uniprot_id": "UXS1_DANRE", "id": "Q6GMI9-1", "name": "UDP-glucuronic acid decarboxylase 1", "aln": "---MMRMSWMVTVINRRMMKILIALALIAYIAS---------------VWGTYAN--MRSIQ----EHGEMKIEQ-----RIDEAVGPLREKIRELELSFTQKYPPVKFLSEKDRKRILITGGAGFVGSHLTDKLMMDGHEVTVVDNFFTGRKRNVEHWIGHENFELINHDVVEPLYIEVDQIYHLASPASPPNYMYNPIKTLKTNTIGTLNMLGLAKRVGARLLLASTSEVYGDPEVHPQNEDYWGHVNPIGPRACYDEGKRVAETMCYAYMKQEGVEVRVARIFNTFGSRMHMNDGRVVSNFILQALQGEALTVYGSGSQTRAFQYVSDLVNGLVSLMNSNISSPVNLGNPEEHTILEFAQLIKSLVASRSHIQFLPEAQDDPQRRRPDIRKAKLLLGWEPVVPLEEGLNKTIQYFSRELEHQANNQYIPKPKAARMKKGRPRHN-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSE8-1", "uniprot_id": "Q9VSE8_DROME", "id": "Q9VSE8-1", "name": "UDP-glucuronic acid decarboxylase 1", "aln": "MTATKKRLKIVAAISLLLLLLVYLYRMASFCPSGKVAVSVPGVEEVQAKWPPTESPLQRSLQMAYEEQSSLIREQKAELQRTRENLARLEEQVRSLQTSTPRKYPKVKYLNYKNRKRILITGGAGFVGSHLVDDLMVQGHEVIVVDNFFTGRKRNVEHWLGHENFELIHHDIVNPLFIEIDEIYHLASPASPPHYMYNPVKTIKTNTMGTINVLGLAKRVMAKVLIASTSEVYGDPTVHPQPETYWGHVNPIGPRACYDEGKRVSETLSYAYAKQEKVQVRVARIFNTYGPRMHMNDGRVVSNFILQALRNETITVYGNGKQTRSFQYVSDLVDGMIALMASNYTQPVNLGNPVEQTIGEFAEIIKKLVGGPSVIKQSKAMEDDPQRRKPDITRARQLLHWEPKVPLETGLQRTISYFRNELARSDRFQ-------ESSNKYFDTHTP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: :. : :: : :: .* * . **:* *:..: *. : * : *.*::*.*: * .:*** **:*. *:*****************.*.**::**** ****************:********:**:*:**:**:*:***********:*****:**:****:**:*:******* *::*:********** **** * ********************:**:.*** *** *:*********:*.******************:.*.:****.*.***:********:*:::** ** :.******* *:** ***::**.**.. * *: :****:*:*** :*: :* *** **** **:::* ** .** . . * :* *. ", "identical_positions": 251, "similar_positions": 90, "identity": "56.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020419-38", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJF7-1", "uniprot_id": "D3ZJF7_RAT", "id": "D3ZJF7-1", "name": "Telomeric repeat-binding factor", "aln": "MAAGAGTAGPASGPGVVRDPMASQPRKRP------GGEGARRSNTMAGGGGSSDNGGRAANRRASRSGGRARRGRHEPGLGGAAERGAGEARLEEAVNRWVLKFYFHEALRAFRSSRYRDFRQIRDIMQALLVRPLGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTDSMVESSRRLVKEAAVIICIKNKEFEKASKILKKYMSKDPTTQKVRTDLLNIIREKNLAHPVIQNFSYEIFQQKMLRFLESHLDDTEPYLLTMAKK----ALRSESAASSTMKEEKHTEP--VEKPLREPP-RQPRNPPTTIGLRTVKAAFKALSTAQDSEAAFAKLDQKDLVLPNLASPSSPTHKNKRPRKDENESSAPAEGEGGSERQPRNNR-MTISRLVLEEDSQSSEPSPDLNSSRQ-------------------------------------------------------------------------------------ALSASPSKPRALNQPHTGEKNPKASKDKWNSPNGLEE-----------------------------------------------------------------KEVWSEEDQLFEVR-APGEDKSSNLARKQKWTIEESEWVKDGVQKYGEGNWVAISKSYPFVNRTAVMIKDRWRTMKKLGLN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35144-1", "uniprot_id": "TERF2_MOUSE", "id": "O35144-1", "name": "Telomeric repeat-binding factor 2", "aln": "MAAGAGTAGPASGPGVVRDPMASQPRKRPSREGGEGGEGERRSNTMAGGGGSSDSSGRAASRRASRSGGRARRGRHEPGLGGAAERGAGEARLEEAVNRWVLKFYFHEALRAFRSSRYRDFRQIRDIMQALLVRPLGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTDSMVESSRKLVKEAAVIICIKNKEFEKASKILKKYMSKDPTTQKLRTDLLNIIREKNLAHPVIQNFSYEVFQQKMLRFLESHLDDTEPYLLTMAKK----ALKSESAASSTMREEKHPEP--VEKPLREPPSRQPQNPPATIGIRTLKAAFKALSTAQDSEAAFAKLDQKDLVLANLASPSSPAHKHKRPRKDEHESAAPAEGEGGSDRQPRNSP-MTISRLLLEEDSQSTEPSPGLNSSHK-------------------------------------------------------------------------------------AMSAS--KPRALNQPHPGEKKPKASKDKWNSPNGLEE-----------------------------------------------------------------KEVWLEEDQLFEVQ-APGEDRSSSLTRKQKWTIEESEWVKDGVRKYGEGNWAAISKSYPFVNRTAVMIKDRWRTMKKLGMN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15554-3", "uniprot_id": "TERF2_HUMAN", "id": "Q15554-3", "name": "Telomeric repeat-binding factor 2", "aln": "MAAGAGTAGPASGPGVVRDPAASQPRKRPGRE---GGEGARRSDTMAGGGGSSDGSGRAAGRRASRSSGRARRGRHEPGLGGPAERGAGEARLEEAVNRWVLKFYFHEALRAFRGSRYGDFRQIRDIMQALLVRPLGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQNFSYETFQQKMLRFLESHLDDAEPYLLTMAKK----ALKSESAASSTGKEDKQPAPGPVEKPPREPA-RQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPKNKR-MTISRLVLEEDSQSTEPSAGLNSSQE-------------------------------------------------------------------------------------AASAPPSKPTVLNQPLPGEKNPKVPKGKWNSSNGVEE-----------------------------------------------------------------KETWVEEDELFQVQAAPDEDSTTNITKKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRLGMN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ART8-1", "uniprot_id": "A0A8M3ART8_DANRE", "id": "A0A8M3ART8-1", "name": "", "aln": "-----------------------------------------------------------------------------------MSDKPCEPSWEQIVNRWSFDFYAFQAFSAFRNGDYTAFTHFINIIESVVVRPVDGHPDMIPQLRLMQFLSRINNGDKLDLTFEEP--KTPLESALDVLESICRDMSVPHPEQQLIRHAISEMLVMVCIRSGEFEKAEEMLKHFSSSSDSAGKKK-LLLNLIRCRRSSHSVLQLSSYSHFKQDMLQFVERLFSVPEPFLLQMLRRSGWPSQRPEVRRSTQNNRRFTGKPSKRTPPHSSAAEDHGAECVSAVSRQGLQQVFDLLSEQYGVGISFFQLQDSVEVEAQQQQEGGVAGPELCLTLSETPMQTVILSDTEEQDEPRRYAGMTISRLVQEEDSQISAEHTHIEDDEEEEQTHTHRGGDWVVVLSDLESDDLDVQAGPVSSPSLRHTPKNRQNQHSSLSEPQCSSTQRSTPARLCKRSNTRVQQSESESQSSPAHCSTPARPSHPSNPRSSTRKKTPSRRRIIESSDSENEQTTPAAATHTPRGQRQQHRSIRVSSGSEPEVDSTSPAAHTRRSTPTSTHTRTTKRSKWLDASGIQDNWSDEDSLFHTSTAPAKKYT-----RKMWSVQESEWLKQGVVRYGVGHWERIRSSFPFAGRTAVNLKDRWRTMVKLKMV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . *. *: **** :.** .:*: ***.. * * :: :*:::::***:. . : **:** ****::*::** :*: ******::*** * ::::... : *: :.* *::**:. *****.::**:. *.. :: * : ***:** :. :*.*:* **. *:*.**:*:* :. .**:** * :: : :.* *: .. * * ... : : :::. :: .*. ** . :* :*::. * . .. : . .* : .: .: :*:. ******: ***** : . ::...: * .:. :* .:* .. :: . .: : .... *: :: * :**.**.. ** :. : :: *:::****:* ** :** *:* * ..:**..**** :******* :* : ", "identical_positions": 136, "similar_positions": 166, "identity": "19.4%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020419-39", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KB96-1", "uniprot_id": "A0A0G2KB96_RAT", "id": "A0A0G2KB96-1", "name": "", "aln": "-------------------------MSFPLSTAFTVSHTFG------------------------KPKLTVTEKAIRLAYRHAKQSKK-NVPCFLLGSLTVDEDEEGVTLTIDRFDPGRETRECLERTPTAALPGDFLIPCKVHTQGLCSRDTKVHNADDFSSALKALQHHVCSKDLLDCGKLLSLRAQITPRESLGGVDLNLQWTAVTLANPFKCIPVKPIPIIPTALARNLSSSLNISQVQGTCKHGYITMDETRKLLLLLESDPKVYSLPLVGIWLSGIIHIYSPQVWACCLRYMFSSSIQERVFSESGNFIIVLYSLTHKEPEFYECLPCDSRTPELQFQLLTNKETFHLFKNVEPSSKNLMHFELSAESQD--AEAEAKLFSKISKDLSVKRASQKVSPGKIPINKRDTDLEDEDFSPRPIPSPHPVSQKISKIQPSVPELSLVLDNNFTESSNPSKPVEVMAVENPLLI------KPSQPELCDDKHSSEANTGEPFLRGLPNQLSQDT--ALRQCRGKQS---STCMKESLPFRSTNAKPSLNAPSPDVAEKLQAVSAGSMSKEDYPVRPSLLDSRQPSLAPQAHPHN-LVFSPHNSTRPMELQVPTPSLP----SYYSTNVCSCCQHHGHIQYSTIN-SWQG-NTVGSVQDLRSEALPKHAFFHSSG-----CPSLCPNAIYSSSSPVTMKPQGGVDTYSPHSNGEPSPVAG-PSHVDSCVPHPCAVCMHTPTTA--PDNGMMGLSPDAYRFVTEQDRQLRLLQAQIQRLLEAQSLDPGSHKSVATAEDSVKAARQMELVSVEAQSSPGLHMRKSVSIAVSTGASLFWNAAGDDQEHDAQLKQDDTKISSEDMNFSVDINNEATSPPGSASSLKAVDIPSFEESNPAV-EEFNQPLPESNSS-EQRKEPDVPVFFPNALLAESVSMCLQTAPAEGASNSTESPQGTKVE------PFGPSDN-KIYQDLLGQVNHLLSNSSQETDQPPTRAVVINHECTKTQNAHHARKKRHTSGLVDTDCVLSATIKQLRSLGVKIDS-PTKVKKSAQKVDHASVLACISPEAVISGLNYMSFGNIGMSSLSPTG-VDLSMEANAIALRYLSENQLSQLSLAR--SNQNHCDSSLGLLHINSDKSSVGLSLVSPSNMSFATKKYMKRYGLLQSSDNSEDEDEEEPPGHSDSESNRVLNRNPACKPAQCGPERAPSRNACETAQCSNGGSGDTHTDVPVLRNITNQAQQPRAAEHLTQDSAVSLRNLKPHPAVNLRTGKAEFTRHPEKENERDIAVFPELSQSPETLKQMNSMNSVGTFLDVKRLRQLPKLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60988-1", "uniprot_id": "STIL_MOUSE", "id": "Q60988-1", "name": "SCL-interrupting locus protein homolog", "aln": "-------------------------MNTRFPSSKMVPFHFPPSKLALWNPMPIGECIYLHLSYYRKPKLMVTEKAIRLAYRHAKQNKK-NVPCFLLGSLTVDEDEEGVTLTIDRFDPGREIPECLERTPTASLPGDFLIPCRVHIQGLGSRDVIVHNADDFSSALKALQYHVCSKDFLDCGKLLCLRAQITPRESLDGVDFNLQWTAVTLANSFKCVPVKPIPIIPTALARNLSSNLNISQVQGTYKHGYITMDETRKLLLLLQSDPKVSSLPLVGIWLAGIIHVYSPQVWACCLRYMFSSSIQERVFSESGNFIIVLYSLTHKEPEFYECLPCESRTPDLQFQLLTNKETLHLFNNVEPSGKNPIHFELSAESQD--AEAEAEVLSKISKTLPVKRSSQKLSPGKIPINKHDTDLEDEDFSPRPIPSPHPVSQKISKVQPSVPELSLVLDNNFTESSNQSNPLEMMTVENPLLI------KPSQPELCDAKHSSEATTGEPFRRGPTNQLSQDT--ALRQSRGKQS---STCKKESLQFRNTNAKPSLSVPSPDVAEKLQAVSAGSMQKEDYPVRPSTLDSRQPSLAPQAQPHN-LVFSTHNSTRPMELQVPTPSLP----SYYPTNVCSCCQHHGHIQYSTIN-SWQG-NTVGSIQDLRSESLPKHAFFHSSG-----CPSLCPNAIYSSSSPVSMK-QGGMGAYSPHSNGEPSPVAG-PSHVDSCVPHPCAMCMHTPNTA--PDNGMMGLSPDAYRFVTEQDRQLRLLQAQIQRLLEAQSLDPGSHKTVATVEDTVKAAKQMELVSMEAQSSPGLHMRKSVSIAVSTGASLFWNAAGDDQEPDSQPKQDDTKISSEDMNFSVDINNEATSLPGSASSLKAVDIPSFEESNLAV-EEVNQPLPESNSSSEQSKEPGVPVFFPNALLAESVSMCLQTAPTEGASNSTELPQGTKDE------PYRPSDNQKIYQDLLGQVNHLLSNASQETEEPPTKAVVTNRECAKTQNTHHARKKRHNSGLVDKDCVLSATIKQLRSLGVKIDS-PTKVKKNEQKVDHASVLACISPEAVISGLNYMSFGNVGMSSLSPTG-VDLSMEANAIALKYLSENQLSQLSLAR--SKQNNGDSSVGLLHINSDRSTVGLSLVSPSNMSFATKKYMKRYGLLQSSDNSEDE--EEPPSHADSESDHVLNRNPACRPVQCGHEKEPSWNACEIAQCSDCGSADTRTDVPVLRNITNQAVQPRATEHLNEDSAISLRNLKPNPAMNLRTGKAEFTHHPEKENERDIAVFPGTLPSPETLKQMNSMDSVGTFLDVKRLRQLPKLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15468-1", "uniprot_id": "STIL_HUMAN", "id": "Q15468-1", "name": "SCL-interrupting locus protein", "aln": "--------------MEPIYPFARPQMNTRFPSSRMVPFHFPPSKCALWNPTPTGDFIYLHLSYYRNPKLVVTEKTIRLAYRHAKQNKK-NSSCFLLGSLTADEDEEGVTLTVDRFDPGREVPECLEITPTASLPGDFLIPCKVHTQELCSREMIVHSVDDFSSALKALQCHICSKDSLDCGKLLSLRVHITSRESLDSVEFDLHWAAVTLANNFKCTPVKPIPIIPTALARNLSSNLNISQVQGTYKYGYLTMDETRKLLLLLESDPKVYSLPLVGIWLSGITHIYSPQVWACCLRYIFNSSVQERVFSESGNFIIVLYSMTHKEPEFYECFPCDGKIPDFRFQLLTSKETLHLFKNVEPPDKNPIRCELSAESQ----NAETEFFSKASKNFSIKRSSQKLSSGKMPIHDHDSGVEDEDFSPRPIPSPHPVSQKISKIQPSVPELSLVLDGNFIESNPLPTPLEMVNNENPPLINHLEHLKPLQPQLYDEKHSPEVEAGEPSLRGIPNQLNQDKPALLRHCKVRQP---PAYKKGNPHTRNSIKPSSHNGPSHDIFEKLQTVSAGNVQNEEYPIRPSTLNSRQSSLAPQSQPHD-FVFSPHNSGRPMELQIPTPPLP----SYCSTNVCRCCQHHSHIQYSPLN-SWQGANTVGSIQDVQSEALQKHSLFHPSG-----CPALYCNAFCSSSSPIALRPQGDMGSCSPHSNIEPSPVARPPSHMDLCNPQPCTVCMHTPKTE--SDNGMMGLSPDAYRFLTEQDRQLRLLQAQIQRLLEAQSLMPCSPKTTA-VEDTVQAGRQMELVSVEAQSSPGLHMRKGVSIAVSTGASLFWNAAGEDQEPDSQMKQDDTKISSEDMNFSVDINNEVTSLPGSASSLKAVDIPSFEESNIAVEEEFNQPLSVSNSSLVVRKEPDVPVFFPSGQLAESVSMCLQTGPTGGASNNSETSEEPKIEHVMQPLLHQPSDNQKIYQDLLGQVNHLLNSSSKETEQPSTKAVIISHECTRTQNVYHTKKKTHHSRLVDKDCVLNATLKQLRSLGVKIDS-PTKVKKNAHNVDHASVLACISPEAVISGLNCMSFANVGMSGLSPNG-VDLSMEANAIALKYLNENQLSQLSVTR--SNQNNCDP-FSLLHINTDRSTVGLSLISPNNMSFATKKYMKRYGLLQSSDNSEDE--EEPPDNADSKSEYLLNQNLRSIPEQLGGQKEPSKNDHEIINCSNCESVGTNADTPVLRNITNEVLQTKAKQQLTEKPAFLVKNLKPSPAVNLRTGKAEFTQHPEKENEGDITIFPESLQPSETLKQMNSMNSVGTFLDVKRLRQLPKLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JGS1-1", "uniprot_id": "STIL_DANRE", "id": "Q8JGS1-1", "name": "SCL-interrupting locus protein homolog", "aln": "MNRVQVDFKGLPAHILENSIAAESLQNTRSSDNVLTPLTFPKSKVALWDPSANGEVVSLHFSYYRNPRLFLVEKALRLAHRHARQTNKPRFFCFLLGTLAVDSDEEGVTITLDRFDPGREQTGCLGKAPTALLPGDILVPCVFEAQHAAS--STVHSSEDLNISFKMLQHFCCSKELLELSKLLTLRAQLSCSENMDRLTFNLSWAAVTLACTLDAVPIRAVPIIPTALARNLSSPAGVTQNS---KRGFLTMDQTRKLLLILESDPKAYTLPLVGIWLSGVTHIHNPLVWAWCLRYLHSSSLQDKVLSEGGTFLVVLYSLTHRDPEFYQCKPSTGQQ-QLSFQLLTSRDSLTLYKNVEPSEGRPLQFELSSENQNQETVLFEEVLSQSVLTGTTLGAASAAPQNKLSISDHDSGVEDEDLSPRPSPNPHPVSQQTKRVHPLVPELSMVLDGSFLDGSVVNTQGSTPLSHSQSNVHRRNSSPALQGLSVLRPLVQGSVTKPPPIRRPLTPILSQPKNKLHPNPSQQTPQHSVSRKSLPSMRRSREGSSASSVSSSSSSSSTKNASPNGSFHQQRQRLSQGFPNKPQLIYSGPPTSGHSSAKKSSSVPSQTPVPHPSQHRIFHSTPAVNPCNCCTNHPSVAPLYQNNTWQG--TPGYPTAVHSPCVFHCSPETVPPGDHCLSPSRQSLGCRVSPTKSPVCYHSTPPHYSPSSGPCVPTIISNKGLVEQTPSCQAQCCQVKGSKEPCLDTPMGLLPADAYRMLIDQERQLKLLQLQIQKLLESQSKVP---------EVSSEQNAQQQRPNQVPASPP---KRTSVSIAVGTGASLFWSTPQETSTHEAS---------------SLEWQTETEPKSGCQNDSTVTSRDRSESACHYSEEHCPGSPQHPTSPQHNTSSGFGVQMFQSPVLGESASMYYQSQSQSKDLSENREIDDPRFYH-----ELLGQVQSRLQDSVIVEDKVEQDQQSLLKTQSLSPVVHQSRKPLTTSSIPQTQKTKQPSSPPNQDRVLSATLKQLQQFGVNIDLDSSQEKTTRATVESASTLACINPEAVIPRLALS--EPVGASIWGPSGSVDLSLEANAIALKYLSDSQLSRLSLGSQSSSPHSDPSTILLRRPAVEKSNVALSILSPSNMSLATCKYMKKYGLIEGEISSEEE--QEDPIQVDSALG--------------------CSVQHETSKTISLGQEREEQNTAVLKNITNKPVVNLHTSPIDSQ-EQILQDLRPKMQLLLRGGTNSEKENATKRN--LIERRSSLTENQRTQEVVDPQGSVGNFLDLSRLRQLPKLF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .. * :*:* :.**::***:***:*.:* . *****:*:.*.******:*:******** ** :*** ****:*:** .. * * **. :*:. ::* ** . ***: *: .*** **.::: *.:. : ::* *:***** :.. *::.:************* .::* . * *::***:******:*:****. :********:*: *::.* *** ****:..**:*::*:**.*.*::****:**::****:* *. .: :: *****.:::: *::****. . :: ***:*.* :.:*: . ::. . .*:.* .:*:.:****:**** *.******: .:::* *****:***..* :.. . . .. : . * : * * . : .: *: :*. .. * * : .* . * . .. :: . . .: * * ..:..* .. * . : :.* * : :* *. * ..* * ** :* : * :*** * * ::* .: : : . .*: . *.: .: :. ** *. ..: . :: . . * . .. *. * *..****:: :*:***:*** ***:***:** * * : : * : . . *.* *..*****.*******.:. : . ::. *:: :.*. . .*. .. .... *.: *. . ..*. .. :* . *.**.** *: . .... : .: . : :: :.:: : : .. * . :. : .* .:: *.. :::*. : * : * **.**:***:.:**:** .:: *.. .*: **.****.*****. * :* * .*.* ****:*******:**.:.***:**: *. : . . * : ::*.*.**::**.***:** ****:***::.. .**:* :* * : ** . * : . . . :..**:****: . : .. :::*:* : ** *. . ..:. *.* * . .* : ::. .***.***:.*********", "identical_positions": 385, "similar_positions": 383, "identity": "28.95%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020419-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P25205-1", "uniprot_id": "MCM3_HUMAN", "id": "P25205-1", "name": "DNA replication licensing factor MCM3", "aln": "MAGTVVLDDVELREAQRDYLDFLDDEEDQGIYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIDATYAKQYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGYTSGTFRTVLIACNVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQK--VELSESRLKAFKVALLDVFREAHAQSIGMNRLTESINRDSEEPFSSVEIQAALSKMQDDNQVMVSEGIIFLI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RIC5-1", "uniprot_id": "Q5RIC5_DANRE", "id": "Q5RIC5-1", "name": "DNA replication licensing factor MCM3", "aln": "-MAAEVVDDQEMREAQRDYLDFLDDDQDQGIYQSKVRQMISENKSRLIVNLNDLRRRNEKRAAKLLNNAFEELLAFQRALKDLVASIDATYAKQCEEFFIGLEGSFGSKHVSPRTLTSRLLGSMVCLEGIVTKCSLVRPKVVRSVHYCPATKKTMERKYTDLTSLDAFPSSAIYPTKDEENNPLETEFGLSVYKDHQTITIQEMPEKAPAGQLPRSVDIILDNDLVDAVKPGDRTQVIGTYRCLPGKKGGFTSGTFRTIMIACHVKQMSKEISHYFSADDVAKIKSFCRSRSKNVFDQLARSLAPSIHGHEYIKKAILCMLLGGVEKVLENGSRIRGDINVLLIGDPSVAKSQLLRYVLHTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLGDRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRDPHEQDGTALALGGTIDALATEDPDATQEEEEELQVYEKHNPLLHGSKKNKDRVVSKAFMRKYIHVAKAISPVLTQDAANHIAEEYSRLRNQEQLGSDIARTSPVTARTLETLIRLSTAHAKARMSKAVELVDTEVAVELVQFAYFKKVLEKERKRSRNGQQDAASEDEEEEEDEAQDTPRPPRKRRR-GSQGSESYDPYDFN-TETDIPQIQSPAPALQADEEPDQNGHTELSEDRFKEFKAALHKVFRSSHAQSVGLIALMESINKSCPSAFNETDFRAALARMQDDNQVMLADDIIFLI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: *:** *:*************::**********::**:*: *****:*****:***** :*********:********:*********** ***::****************** :*..:**:***************************:**:*:***:* *****::**************:******************************:***:**** .*****.**:************:*******::***:******: . ***:*:****.*.::***::*****:*********:*:******:******: *****:******:****************** ****************************************.*********************************************************************************************************** * **** *:.**.::* ***:**: :**:::: *:****: ****:**:*:::** ***:******* *.*****::*.:*********.*:.:.** *****************:**********:*:* *:* ******:**********:**.:..:::: :*****:.:* *: * ** *: .::..:*******. ** ::**:::* .* . : : .*: .****.*:* **.** .***.:****:*: * ****:.. ..*...:::***::********:::.*****", "identical_positions": 610, "similar_positions": 150, "identity": "75.31%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020419-40", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70126-1", "uniprot_id": "AURKB_MOUSE", "id": "O70126-1", "name": "Aurora kinase B", "aln": "-------------------------------------------MAQKENAYPWPYGSKTSQSGLN-----------------TLSQRVLRKEPATTSALALVNRFNSQSTAAPGQKLAENKSQGSTASQGSQ------------NKQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKS--RTFDEQRTATIMEELSDALTYCHKKKVIHRDIKPENLLLGLQGELKIADFGWSVHAP-SLRRKTMCGTLDYLPPEMIEGRMHNEMVDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSVPSGAQDLISKLLKHNPWQRLPLAEVAAHPWVRANSRRVLPPSAL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O55099-1", "uniprot_id": "AURKB_RAT", "id": "O55099-1", "name": "Aurora kinase B", "aln": "-------------------------------------------MAQKENVYPWPYGSKTSQSGLN-----------------TLPQRVLRKEPAVTPAQALMNRSNSQSTAVPGQKLTENK--GATALQGSQ------------SRQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKS--GTFDEQRTATIMEELSDALMYCHKKKVIHRDIKPENLLLGLQGELKIADFGWSVHAP-SLRRKTMCGTLDYLPPEMIEGRMHNEMVDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSMPLGAKDLISKLLKHNPSQRLPLEQVSAHPWVRANSRRVLPPSAL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96GD4-1", "uniprot_id": "AURKB_HUMAN", "id": "Q96GD4-1", "name": "Aurora kinase B", "aln": "-------------------------------------------MAQKENSYPWPYGRQTAPSGLS-----------------TLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENS----SGTPDIL------------TRH-FTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKS--CTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAP-SLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88445-1", "uniprot_id": "AURKC_MOUSE", "id": "O88445-1", "name": "Aurora kinase C", "aln": "------------------------------------------------------------------------------------------------------------------------------MEPSTS------------TRKHFTINDFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRH--QKLDQQRTATIIQELSDALTYCHEKKVIHRDIKPENLLLGLNGEVKISDFGWSVHTP-SLRRKTMCGTLDYLPPEMIAQKPYNEMVDLWCIGVLCYELLVGKPPFESSTSSETYRRIRQVDFKFPSSVPAGAQDLISKLLRYHPSERLSLAQVLKHPWVREHSRRVLP-C------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AD76-1", "uniprot_id": "D4AD76_RAT", "id": "D4AD76-1", "name": "non-specific serine/threonine protein kinase", "aln": "---------------------------------------------------MLEISRLLVSLGYP-----------------VPNLELLCQREQVQEPWTVVKSPSESTSLATGQ-----------MEPSTS------------TKKHFTINDFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIGKEGLEHQLRREVEIQSHLQHPNILRLYNYFYDDSRVYLILEYAPRGELYKELQRN--QKLNQQRTATIIEELSDALIYCHRNKVIHRDLKPENLLLGLKGEVKIADFGWSVHTP-SLRRKTMCGTLDYLPPEMIEGKSYNETVDLWCIGVLCYELLVGKPPFESSTSSETCRRICQVDFRFPSSMPAGAQDLISKLLRHHPSERLSLAQVLKHPWVRKHSQRMLPPCAQMAS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UQB9-1", "uniprot_id": "AURKC_HUMAN", "id": "Q9UQB9-1", "name": "Aurora kinase C", "aln": "----------------------------------------------------MSSPRAVVQLGKA-----------------QPAGEELATANQTAQ------------------------------QPSSP------------AMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKS--EKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTP-SLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSRRVLPPCAQMAS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NW76-1", "uniprot_id": "AURKB_DANRE", "id": "Q6NW76-1", "name": "Aurora kinase B", "aln": "-------------------------------------------MQNKENR--EPRVQQTPSAGVG-----------------PLRVEMNPDTHAVSGP---------------------------GRVPVKS------------NSKVLSIDDFDIGRPLGKGKFGNVYLARERKLKVVIALKVLFKSQMVKEGVEHQLRREIEIQSHLRHPNILRFYNYFHDDTRVFLILEYAPRGEMYKELQRY--GRFDDQRTATYMEEVSDALQYCHEKKVIHRDIKPENLLLGYRGELKIADFGWSVHAP-SLRRRTMCGTLDYLPPEMIEGHSHDEKVDLWSIGVLCYECLVGNPPFETASHAETYKRITKVDLQFPKLVSEGARDLISKLLRHSPSMRLPLRSVMEHPWVKANSRRVLPPVCSSEPH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGF9-1", "uniprot_id": "Q9VGF9_DROME", "id": "Q9VGF9-1", "name": "Aurora kinase", "aln": "MSHPSDHVLRPKENAPHRMPEKSAAVHNMQKNLLLGKKPNSENMAPASKPLPGSSGALIRKPGLGGSNSIASSEGNNFQKPMVPSVKKTTSEFAAPAPVAPIKKPESLSKQKPTAASSESSKELGAASSSAEKEKTKTETQPQKPKKTWELNNFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFKRQIGESNVEHQVRREIEIQSHLRHPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQPMKRFDERQSATYIQALCSALLYLHERDIIHRDIKPENLLLGHKGVLKIADFGWSVHEP-NSMRMTLCGTVDYLPPEMVQGKPHTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEHISKAASHLISKLLVLNPQHRLPLDQVMVHPWILAHTQ------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38991-1", "uniprot_id": "AURK_YEAST", "id": "P38991-1", "name": "Aurora kinase", "aln": "----------------------------MQRNSLVNIKLN--ANSPSKKTTTRPNTSRINKPWRIS----------------HSPQQRNPNSKIPSPVREKLNRLPVNNKKFLDMESSKIPSPIRKATSSKMIHENKK----LPKFKSLSLDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLH--GPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDAQDLILKLLKYDPKDRMRLGDVKMHPWILRNKPFWENKRL-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::*::*: **:****.** .* :. : ***:: * :: : .:::*.***:***: *.* :: : * **:* *::*::** * ::: *: ::: :: : :..** * * ..:****:****:*:* .. :*::*****: * . * *:***:***.***: : : . :* *.:***.:* :.* .** * ::* :* ::* :. * .** :** * *: * .: ***: :. ", "identical_positions": 90, "similar_positions": 90, "identity": "21.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020423-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P83883-1", "uniprot_id": "RL36A_RAT", "id": "P83883-1", "name": "Large ribosomal subunit protein eL42", "aln": "--------------MVNVPKTRRTFCK--KCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P83882-1", "uniprot_id": "RL36A_MOUSE", "id": "P83882-1", "name": "Large ribosomal subunit protein eL42", "aln": "--------------MVNVPKTRRTFCK--KCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P83881-1", "uniprot_id": "RL36A_HUMAN", "id": "P83881-1", "name": "Large ribosomal subunit protein eL42", "aln": "--------------MVNVPKTRRTFCK--KCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q969Q0-1", "uniprot_id": "RL36L_HUMAN", "id": "Q969Q0-1", "name": "Ribosomal protein eL42-like", "aln": "--------------MVNVPKTRRTFCK--KCGKHQPHKVTQYKKGKDSLYAQGRRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0R7E5-1", "uniprot_id": "M0R7E5_RAT", "id": "M0R7E5-1", "name": "", "aln": "MWRSLVAHVTATPYVVNVPKTRQTFCK--KCGKHQPHKVTQYKMGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKSTKKNVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKCQVIQF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0A6YW33-1", "uniprot_id": "A0A0A6YW33_MOUSE", "id": "A0A0A6YW33-1", "name": "", "aln": "--------------MVNVPKTRQTFCK--KCGKHQSHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLESVEPNCRSKRMLARKRCEHFELGGDKKRKGQVIQF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61485-1", "uniprot_id": "RL36A_DANRE", "id": "P61485-1", "name": "Large ribosomal subunit protein eL42", "aln": "--------------MVNVPKTRRTYCK--KCKKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLT7-1", "uniprot_id": "Q9VLT7_DROME", "id": "Q9VLT7-1", "name": "", "aln": "--------------MVNVPKQRRTFCK--KCKVHKLHKVTQYKKSKERKGAQGRRRYDRKQQGFGGQTKPIFRKKAKTTKKIVLRMECTE--CKYRKQTPLKRCKHFELGGDKKRKGQMIQF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX28-1", "uniprot_id": "RL44B_YEAST", "id": "P0CX28-1", "name": "Large ribosomal subunit protein eL42B", "aln": "--------------MVNVPKTRKTYCKGKTCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKVVLRLECVK--CKTRAQLTLKRCKHFELGGEKKQKGQALQF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX27-1", "uniprot_id": "RL44A_YEAST", "id": "P0CX27-1", "name": "Large ribosomal subunit protein eL42A", "aln": "--------------MVNVPKTRKTYCKGKTCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKVVLRLECVK--CKTRAQLTLKRCKHFELGGEKKQKGQALQF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :***** *:*:** .* * ******* .* ***:*******.*:******:*:****:*** ***:*..: *: : . ***:******:**:* * :**", "identical_positions": 64, "similar_positions": 22, "identity": "52.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020423-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q15904-1", "uniprot_id": "VAS1_HUMAN", "id": "Q15904-1", "name": "V-type proton ATPase subunit S1", "aln": "MMAAMATARVRMGPRCAQALWRMPWLPVFLSLAAAAAAAAAEQQVPLVLWSSDRDLWAPAADTHEGHITSDLQLSTYLDPALELGPRNVLLFLQDKLSIEDFTAYGGVFGNKQDSAFSNLENALDLAPSSLVLPAVDWYAVSTLTTYLQEKLGASPLHVDLATLRELKLNASLPALLLIRLPYTASSGLMAPREVLTGNDEVIGQVLSTLKSEDVPYTAALTAVRPSRVARDVAVVAG-GLGRQLLQKQPVSPVIHPPVSYNDTA--PRILFWAQNFSVAYKDQWEDLTPLTFGVQELNLTGSFWNDSFARLSLTYERLFG-TTVTFKFILANRLYPVSARHWFTMERLEVHSNGSVAYFNASQ-VTGPSIYSFHCEYVSSLSKKGSLLVART---QPSPWQMMLQDFQIQAFNVMGEQFSYASDCASFFSPGIWMGLLTSLFMLFIFTYGLHMILSLKTMDRFDDHKGPTISLTQIV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R1Q9-1", "uniprot_id": "VAS1_MOUSE", "id": "Q9R1Q9-1", "name": "V-type proton ATPase subunit S1", "aln": "MMAATVVSRIRTGTGRAPVMWLS------LSLVAVAAAVATEQQVPLVLWSSDRNLWAPVADTHEGHITSDMQLSTYLDPALELGPRNVLLFLQDKLSIEDFTAYGGVFGNKQDSAFSNLENALDLAPSSLVLPAVDWYAISTLTTYLQEKLGASPLHVDLATLKELKLNASLPALLLIRLPYTASSGLMAPREVLTGNDEVIGQVLSTLKSEDVPYTAALTAVRPSRVARDITMVAG-GLGRQLLQTQVASPAIHPPVSYNDTA--PRILFWAQNFSVAYKDEWKDLTSLTFGVENLNLTGSFWNDSFAMLSLTYEPLFG-ATVTFKFILASRFYPVSARYWFAMERLEIHSNGSVAHFNVSQ-VTGPSIYSFHCEYVSSVSKKGNLLVTN----VPSVWQMTLHNFQIQAFNVTGEQFSYASDCAGFFSPGIWMGLLTTLFMLFIFTYGLHMILSLKTMDRFDDHKGPTITLTQIV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2AR67-1", "uniprot_id": "A2AR67_DANRE", "id": "A2AR67-1", "name": "", "aln": "-MTEVGMRRCSLLTMAFTS-----------VLLFICSIYSCYAQVPLLMWTSDGSSMPHLAEAAAGHTVSGGQLVSYLRSALSTAPHNVLIFLQDQLSIEDFTMYGGVFGNKQDSAFLNIESALQTSSSPLVLSALDWTASHSVLDLFQKELSVSAVHIDTNTLNEMKLNNTQPSLLAVRLLYTAGS---QSKEMLLKNDMIIGEVLDMFKSQDMPYTAVYTGLKPSRIIEDTPVMAGFSMGRSLLQTPPPQ-SEKPPLVFNDTAGQPCIMLWADTLLAAYDGNQADLASNIFN-STPDTTGSFCNETVSRLVLNYRNILNLQSLQLIFSMSKIFFPVSARNWTVMDQVVLEYDGQRAMFNASAGINTPAEYSFRCQNVS--SAQSPLLVPRNATDNATKWTLIFTDFQIQSFSVTGDSFAFASDCAGFFSAGIWMGLVISLLMLLILTYGLHMIMQLRTMDRFDDPKGPAISVPLSE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: * . * .: : ****::*:** . . *:: ** .*. ** :** .**. .*:***:****:******* ************* *:*.**: :.*.***.*:** * :: :*::*..*.:*:* **.*:*** : *:** :** ***.* .:*:* ** :**:**. :**:*:****. *.::***: .* .::** .:**.***. . :**: :**** * *::**:.: .**..: **:. *. . : **** *::.: * *.*. ::. :: : * ::. ::***** * .*::: :. :*. * **.* :. *: ***:*: ** * :. ***.. .: * : : :****:*.* *:.*::*****.***.******: :*:**:*:*******:.*:******* ***:*::. ", "identical_positions": 200, "similar_positions": 145, "identity": "41.84%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020423-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68FR6-1", "uniprot_id": "EF1G_RAT", "id": "Q68FR6-1", "name": "Elongation factor 1-gamma", "aln": "MAAGTLYTYPENWRAFKALIAAQYSGAQIRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDDGFCVFESNAIAYYVSNEE---------LRG-STPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVKRILGLLDTHLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAILGEVKLCEKMAQFDAKKFAESQPKKDTPRK-EKGSREE-KQKPQ----TERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLPKSTFVLDEFKRKYSNEDTLSVALPYFWEHFDKDGWSLWYAEYRFPEELTQTFMSCNLITGMFQRLDKLRKNAFASVILFGTNNSSSISGVWVFRGQDLAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWEG--AFQHVGKAVNQGKIFK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D8N0-1", "uniprot_id": "EF1G_MOUSE", "id": "Q9D8N0-1", "name": "Elongation factor 1-gamma", "aln": "MAAGTLYTYPENWRAFKALIAAQYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDDGFCVFESNAIAYYVSNEE---------LRG-STPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVKRILGLLDTHLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAILGEVKLCEKMAQFDAKKFAESQPKKDTPRK-EKGSREE-KQKPQ----AERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLPKSTFVLDEFKRKYSNEDTLSVALPYFWEHFDKDGWSLWYAEYRFPEELTQTFMSCNLITGMFQRLDKLRKNAFASVILFGTNNSSSISGVWVFRGQELAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWEG--TFQHVGKAVNQGKIFK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P26641-1", "uniprot_id": "EF1G_HUMAN", "id": "P26641-1", "name": "Elongation factor 1-gamma", "aln": "MAAGTLYTYPENWRAFKALIAAQYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDDGFCVFESNAIAYYVSNEE---------LRG-STPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVRRILGLLDAYLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAVLGEVKLCEKMAQFDAKKFAETQPKKDTPRK-EKGSREE-KQKPQ----AERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLPKSTFVLDEFKRKYSNEDTLSVALPYFWEHFDKDGWSLWYSEYRFPEELTQTFMSCNLITGMFQRLDKLRKNAFASVILFGTNNSSSISGVWVFRGQELAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWEG--AFQHVGKAFNQGKIFK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PE25-1", "uniprot_id": "EF1G_DANRE", "id": "Q6PE25-1", "name": "Elongation factor 1-gamma", "aln": "MAAGTLYTYPENWRAFKAQIAAQYSGARLKIASAPPAFTFGQTNRSPAFLGNFPLGKVPAYQGDDGFCLFESNAIAHYLSNDV---------LRG-STPQASAQVLQWVSFADSEVIPPASAWVFPTLGIMQFNKQATEQAKEEVKRVLAVLNQHLNTRTFLVGERISLADITVVCSLLWLYKQVLEPAFRQPYPNVTRWFVTCVNQPQFKTVLGEVKLCEKMAQFDAKKFAEMQPKKEAPIKKEKGGKEGGKQQPQQQEKKEKKKEEKKAAPA-EEEMDECEAALASEPKAKDPFAHLPKSSFVMDEFKRKYSNEDTMTVALPYFWDHFDREGFSIWYAEYRFPEELTMAFMSCNLITGMFQRLDKLRKNAFASVILFGANNDSCISGIWVFRGQDLAFPLSDDWQIDYESYTWRKLDVDSEECKTMVKEYFAWEG--EFKHVGKPFNQGKIFK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NJH0-1", "uniprot_id": "EF1G_DROME", "id": "Q9NJH0-1", "name": "Elongation factor 1-gamma", "aln": "MVKGTLYTYPENFRAYKALIAAQYSGAQVKVADN---FKFGETNKSAEFLKKFPGGKVPAFETAEGQYLSESNAIAYLLANEQ---------LRGGKCPFVQAQVQQWISFADNEIVPASCAWVFPLLGILPQQKNS--TAKQEAEAVLQQLNQKLQDATFLAGERITLADIVVFSSLLHLYEYVLEPSVRSAFGNVNRWFVTILNQKQVQAVVKDYKLCEKALVFDPKKYAEFQAKTGAAKPQQQAQQQKQEKKPK-----EKKEAPKKAAEP-AEELDAADEALAAEPKSKDPFDALPKGTFNFDDFKRVYSNED-EAKSIPYFFDKFDAENYSIWFGEYKYNEELSKVFMSCNLITGMFQRLDKMRKAAFASVCLFGEDGNSTISGIWVWRGQDLAFTLSPDWQIDYEVYDWKKLDAKSEETKKLVTQYFSWSG--TDKD-GRKFNQGKIFK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P29547-1", "uniprot_id": "EF1G1_YEAST", "id": "P29547-1", "name": "Elongation factor 1-gamma 1", "aln": "MSQGTLYANFR-IRTWVPRGLVKALKLDVKVVTPD--------AAAEQFARDFPLKKVPAFVGPKGYKLTEAMAINYYLVKLSQDDKMKTQLLGADDDLNAQAQIIRWQSLANSDLCIQIANTIVPLKGGAPYNKKSVDSAMDAVDKIVDIFENRLKNYTYLATENISLADLVAASIFTRYFESLFGTEWRAQHPAIVRWFNTVRASPFLKDEYKDFKFADKPLS--PPQKKKEK---------------------------KAPAAAPAASKKKEEAKPAATETETSSKKPKHPLELLGKSTFVLDDWKRKYSNEDTRPVALPWFWEHYNPEEYSLWKVTYKYNDELTLTFMSNNLVGGFFNRLSASTKYMFGCLVVYGENNNNGIVGAVMVRGQDYVP--AFDVAPDWESYDYAKLDPTNDDDKEFINNMWAWDKPVSVNGEPKEIVDGKVLK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P36008-1", "uniprot_id": "EF1G2_YEAST", "id": "P36008-1", "name": "Elongation factor 1-gamma 2", "aln": "MSQGTLYINRS-PRNYASEALISYFKLDVKIVDLE--------QSSE-FASLFPLKQAPAFLGPKGLKLTEALAIQFYLANQVADEKERARLLGS--DVIEKSQILRWASLANSDVMSNIARPFLSFKGLIPYNKKDVDACFVKIDNLAAVFDARLRDYTFVATENISLGDLHAAGSWAFGLATILGPEWRAKHPHLMRWFNTVAASPIVKTPFAEVKLAEKALTYTPPKKQKAE---------------------------KPKAEKSKAEKKKDEAKPADDAAP--AKKPKHPLEALGKSTFVLDDWKRKYSNDDTRPVALPWFWEHYNPEEYSIWKVGYKYNDELTLTFMSNNLVGGFFNRLSASTKYMFGCLVVYGENNNNGIVGAVMVRGQDFAP--AFDVAPDWESYEYTKLDPTKEEDKEFVNNMWAWDKPVVVNGEDKEIVDGKVLK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **** * : . . ::: : * ** :.**: .* : *: ** . : : * . :*: :* *:*:.:: . ... * :*: . : :: *. *::. *.::*.*: . :: . * . *** * . .: : *:.:* . : : : : * * : *.*.*: * *.:* :*::** ***:* . ::*:*::::: : :*:* *:: :**: .*** **: *:*:**. * *..: ::* :... * * : ***: . : * *:* * : *** .:: : :: : ::*. : : . :**::*", "identical_positions": 84, "similar_positions": 123, "identity": "18.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020423-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R9L0-1", "uniprot_id": "M0R9L0_RAT", "id": "M0R9L0-1", "name": "", "aln": "MPGEATETVPATEQELPQPQAETAVLPMSSALNVTAAPGQPGS--PSPSSLGPQQSPLVTAAHQS-SPLPSSLPSTPFEVPFAQP---ETAVPSGAAPPAPTFLPHLIGPPISPAALALASPVIGPAQKGARSSSAPLSLVALAPHSIQKSSVCPPHPLTLPPSAAGAESGALTSLTASIPLLESKASTSQVPSQGTPNLKGTTTPCPPDVVSAFPSHLENPLASVQPGLTSCPQT-----LSITSP-VKGVPISSALT--QSLLSLNLRGPVSSP---------------PQSTVTPSIPPAASASLGSPLPLLHHSSLDSPVQPPGQSGLTVN-----TTISVDHPFVAASYPPERSAVSPLPSRHELAADSG-----AAPSIDKGSSAVTKETCSSSGSANEAG-TSLSPAAPLTPKSSNAALQPSVTQVPPPQKPGLKETPASCIRAMHPALDNPSTMSVAP------ATHVSPPASSGLIKSEDPASPVSSLSVPAAHKPFPAPSMSTTLGIPVSP-LPATEGLQNLPISVN----------------AGAPVSPAQAGLPIRKDTTVQTLAPVALKESPSSQSASSLEVLSED-----TKKTTGGPAPVVRPAIA---TGAPTTLDYPP-----AGYVNPNPVSQPLKSS--APAMAPFLSESCDSKGLVPRTAKDTFPSVNSPLVPLPSEGCPVAPSMALSHQNASVSVTTAKS-------VPFPAPPSAGVSFSSAKKVDVVSQMESSDSSQEGHPNASVSSQT---KRPASKKG---SFPSDVSPGNVSSPHCSLETSFLPEAGLSFQGPKG----------------------------ASIVPTETSVSSKKTPAEILPSPQKTPTATASRLTSAVQSPKLDPTVSDVIPAT-------VVPRDTSASLSLKSVPAVTSLSSQKAPAAPSPNEALVAPTEIPTSLKNALATTAPKETLATSTLKVASTAPVVTSPSPQKTPKSVSPKGAPAVTSKKAKEIAASKEVSTSQFPKEAPLLPHAAPTSPPKSPATDPLNGALTSPSPKVAPATLVESPTSPKKAPKTAAPKETPVTPSLEGVTAVPLEINPCPKKAPKTSTPKESSVTLSSKRTPKSAVSKEIPSNEVTAVPLEISLPLKETSKSAIPVEKSTSSSKSSPKTVAPKETLPEEVTAVPLEVSLPPKEMPQNASP------------------RETPPEGVTAVPLEIPPTPKKAPKTSVPKQIPVTPSPKDAFTTLAESPPSPKKAPTTAAPKEVPAAPSVGITAVS-EISPSPKKTSKTAVPKEDSATSYPKRSPKTATPKENSTSSPKRSPKIEAPKETLATSPEGVTAMPLEIPPSPAAPASKRVPVTPSPKGASNTLAESSASPKKAPKTAAPKETS-TPSPQKIPKMSGPKETPATPPSKKSPKTVAPKETSAPSEGVTALPLKVPPSPRKAPKTAVPKETPAPSPEGVTTALVQIPPSPRK-VKRTSSKETPTNPSPEGVTAAPLEIPLTSKKNPKMASPKEMLVTPPSKKVSQTGDPKETPPEGVTAVPLEILPSPKKTPKTVVPKQVPVTPSPKDAPTTLAESPPSPKKAPTTAAPPSERVTTAPPEKPATPQKASATVASKVLVPAETLEVAVS----------PKETHPSSHKKTPKTVDLKEGPAALPPSPTKSPKISSSKKAQNTSAPIEFPASSSIKAVTTSLAQTVP-CVQKAPSTIAPQENSAAPVAIPVSNKS-PAAPTTANASVALAAASLSPTPQVKISPSKKTPATSALQTVPKEATTIPSGKKAPAIETSNETSTTLSLKGAPKETSETSTSKGVLTSTVNSSSPKKVPSS---KRASTLPATTLPSIKEASVLSPVPTSSTKDSHTYPVSTACSTATTTPQASEKLPAKKEPAALTEVPAAPAPESALAITVPIQKVPRTKRNSA-SPPKCPDPSAKKDTKGLLSAVALAPQTVPVEKNSSKPIEVLPLCPAKGSDSVHSPKGPM---ESQEATPQAAFTSDKVLPKAVSKSVAPKPTLAASLTLAPSPVPPLPPKQPFLQSAPESVLESPSKLPVPADEDELPPLIPPEAVSGGVPFQPILVNMPTPKPAGIPAPAPSAKQPVLKNNKGSGTESDSDESVPELEEQDSTQTATQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEA----------------VSNIQENTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BZK3-1", "uniprot_id": "NACP4_HUMAN", "id": "Q9BZK3-1", "name": "Putative nascent polypeptide-associated complex subunit alpha-like protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGEATETVPAIEQQLLQPQAET--GSGTESDSDESVPELEEQDSTQ-VTAQVQLVVAAEIDEEPVSKAKQRRSEKKARKARFKLGLQQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYMVFGEAKIEDLSQEAQLAAAEKFKVQGEA----------------VSNIQENTQTPTVQEGSEDEEVDETGVEIKDIELVLSQANVWGAKAVRALKN-SNDIVNAIMELTM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JIU7-1", "uniprot_id": "NACA_DANRE", "id": "Q8JIU7-1", "name": "Nascent polypeptide-associated complex subunit alpha", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGEATETVPVTEQEMQQPQAET--GSGTESDSDESVPDLEEGDSAQTQTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVAGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEA----------------VSNIQENTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNNNDIVNAIMELTM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E9PAV3-1", "uniprot_id": "NACAM_HUMAN", "id": "E9PAV3-1", "name": "Nascent polypeptide-associated complex subunit alpha, muscle-specific form", "aln": "MPGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSS-SGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGT--PSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGS-VQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATY---------HYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPK-EPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASS---MTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTS-TYTTTASPFLEGTVSLAP---KNHPVKEGTLTTLPL-------VPT-ASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAG---TPPGTKKVDGISHTSALAPVASSPKECPTEDSGASAT-------------------------------------ASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEAS-------FLPENSLSFQGSKDSPATT-----HSPTPPSPKGAPTPSAVTPLSPKGV--TLPPKETPTPSVVNLPFPKEGPATPAPKQAP----ALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPAT---------PSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAAT---------PPSPKGGPATPSPKGAPT------PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATP---SLKGAPTPPAATP------------------PSPKGGPATPSPKGAPMPP--AATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA--TPPS-PKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT--PSPKGAPTTPAATPPSPKGGL-----ATPSPKGAPTTPAATPPSPKGGPATPPPKGAP-TPPAATPPSLKGGLATP-------------------PHKGAPNPAVVTPPSPKGGPATSPPKGA--PTPPAATPPSPKGSPGTPP-PKGAPTPPAVTPPSPKGTPTLPATT-PSSKGGPTTPSSKEGPT-PPAATPSHKGGPAMTPPS---------------------PKRGPAIPSPKGDPTSPAVIPLSPKKAP---------ATPVTREGAATPSKGDLT---------------------------PPAVTPVSLKKAPATSAPKGGPA------TPSSKGDPTLPAVTPPSPKEPPAP--------KQVATSS-SPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVT-PSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAP-LLPVQKDSSKT--------AKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEA----------------VSNIQENTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9H009-1", "uniprot_id": "NACA2_HUMAN", "id": "Q9H009-1", "name": "Nascent polypeptide-associated complex subunit alpha-2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGEATETVPATEQELPQSQAETGSGTASDSGESVPGIEEQDSTQTTTQKAWLVAAAEIDEEPVGKAKQSRSEKRARKAMSKLGLLQVTGVTRVTIWKSKNILFVITKLDVYKSPASDAYIVFGEAKIQDLSQQAQLAAAEKFRVQGEA----------------VGNIQENTQTPTVQEESEEEEVDETGVEVKDVKLVMSQANVSRAKAVRALKNNSNDIVNAIMELTV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70670-1", "uniprot_id": "NACAM_MOUSE", "id": "P70670-1", "name": "Nascent polypeptide-associated complex subunit alpha, muscle-specific form", "aln": "MPGEATETVPATEQELPQPQAETAVLPMSSALKV-AAVGQPGP--TPPSSLGPQQSPIVTAHQPS--PLPSSVSSTPFEVPFAQPITAETALPSGTAPPTPTFLPHLIGPPISPAALALASPMIGLAQKGARSSSAPLSLVALAPHSVQKSSVCPPHPLTSPPSAAGAELG---ALTASIPPLEPKTSTSQVPSQGTLNLKGT-APCPPDVVRAFPSHLENPLASVQPGLMSCPQT-----LSNTSP-VKGVPISSALT--QSRLSLNLKGPVSPP---------------ARNTAAPSIPLAPSTSLGCHLPLLHHSSVDSPIQPPGQSGLAVS-----NPTSVGHSGIAASCPPERCVVPALPSRLLAVDSG------AAPSDDKGSSAVTNELCSPPGSSNVAG-TSLSPKASLVPKGSNVALQPLVTQVPASQKTGLKEIPVSCIGATHHALDNPSAISVAP------ATHVPPPTSSGLVSSKDPASPVTSLVVPAAHKQFPAPPASATLGVPVSP-LPATEGLKNLPISALVN--------------VGAPVSPAQAGLPTRKDTTLQPLAPIALKESPSSQSASSLEVLSED---TVTKKTTGGPAPVVRPAIAGVATTTSLRADSPPAVIRADSCVSPNTVSQPLKRSVTDPAMAP-------------RTAKNTAPSTTSPLVPLASEGCPVASSMALSPQNASVSETALALSPEIPKSVPFPDPPLAEISFSNARKVDAVSHMESSGSSRQGHPDASVTAKGTVVCLADSSLDTSVSASKGSALSGASSPLYPLEVSFLPEAGLAVQGPKGSLNKLSPTPPSSKGAPVPSTGAPPSPKGAPIVPTESSISSKQVPAEILPSPQKTPEVTASRLISAVQSPKVDPIMSDVTPTSPKKTSATAVPKDTSATLSLKSVPAVTSLSPPKAPVAPS-NEATIVPTEIPTSLKNALAAATPKETLATSIPKVT-------SPSPQKTPKSVSLKGAPAMTSKKATEIAASKDVSPSQFPKEVPLLPHVPPTSPPKSPVSDTLSGALTSPPPKGPPATLAETPTYPKKSPKPAASKKTPATPSPEGVTAVPLEIPPCSKKAPKTAAPKESSATSSSKRAPKTAVSKEIPSKGVTAVPLEISLPLKETSKSATPGEKSASSPKRSPKTAGPKETPPGGVTAVPPEISLPPKETPQNATPNESLAASSQKRSPKTSVPKETPPGGVTAMPLEIPSAPQKAPKTAVPKQIP---TPEDAVTILAGSPLSPKKASKTAAPKEAPATPSVGVIAVSGEISPSPKKTSKTAAPKENSATLPPKRSPKTAAPKETPATSS-----------------EGVTAVPSEISPSPPTPASKGVPVTLTPKGAPNALAESPASPKKVPKTAAPEETSTTPSPQKIPKVAGPKEASATPPSKKTPKTAVPKETSAPSEGVTAVPLEIPPSPRKAPKTAAPKETPAPSPEGATTAPVQIPPSPRKGSKKAGSKETPTTPSPEGVTAAPLEIPISSKKTSKMASPKETLVTPSSKKLSQTVGPKETSLEGATAVPLEIPPSHKKAPKTVDPKQVPLTPSPKDAPTTLAESPSSPKKAPKTAAPPSERVTTVPPEKPATPQKASATTASKVPVPAETQEVAVSSRETPVTPAVPPVKNPSSHKKTSKTIELKEAPATLPPSPTKSPKIPSSKKAPRTSAPKEFPASPSIKPVTTSLAQTAPPSLQKAPSTTIPKENLAAPAVLPVSSKS-PAAPAAASASLSP--------------------ATAAPQTAPKEATTIPSCKKAAATETPIETSTAPSLEGAPKETSETSVSKVLMS-----SPPKKASSS---KRASTLPATTLPSLKEASVLSPTATSSGKDSHISPVSDACSTGTTTPQASEKLPSKKGPTAFTEMLAAPAPESALAITAPIQKSPG-ANSNSASSPKCPDPSSKKDTKGLPSAVALAPQTVPVEKDTSKAIETLLVSPAKGSDCLHSPKGPVG---SQVATPLAAFTSDKVPPEAVSASVAPKPAPAASLTLAPSPVAPLPPKQPLLESAPGSVLESPSKLPVPAEEDELPPLIPPEAVSGGEPFQPILVNMPAPKPAGTPAPAPSAKQPVLKNNKGSGTESDSDESVPELEEQDSTQTATQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEA----------------VSNIQENTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q94518-1", "uniprot_id": "NACA_DROME", "id": "Q94518-1", "name": "Nascent polypeptide-associated complex subunit alpha", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPELTEIKSEAAPSTSAEAK-PEDVRVEDDGSDSDSDGGMPGLEE--AVAATTQLGGGATGLPID--LVSKAKQSRGEKKARKIMLKLGLKQIQGVNRVTIRKSKNILFVINNPDVYKNPHSDTYIVFGEAKIEDLSQQAQVAAAEKFKAPEAAG--------------AADSVGATTSVAPIAEE-DEEDVDDTGVDEKDIELVITQANTTRAKAIKALKNNNNDIVNAIMELTML", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38879-1", "uniprot_id": "NACA_YEAST", "id": "P38879-1", "name": "Nascent polypeptide-associated complex subunit alpha", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAIPENANVTVLNKNEKKARELIGKLGLKQIPGIIRVTFRKKDNQIYAIEKPEVFRS-AGGNYVVFGEAKVDNFTQKLAAAQQQAQASGIMPSNEDVATKSPEDIQADMQAAAEGSVNAAAEEDDEEGEVDAGDLNKDDIELVVQQTNVSKNQAIKALKAHNGDLVNAIMSLSK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : :.**:**: **** *: *: ***: *..* ::.* : :*::. .. *:******:::::*: * : . : .. * :: :** .:: .*::**: *:*. :*::*** ..*:*****.*: ", "identical_positions": 45, "similar_positions": 54, "identity": "1.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020424-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q07243-1", "uniprot_id": "MTF1_MOUSE", "id": "Q07243-1", "name": "Metal regulatory transcription factor 1", "aln": "---------------------------MGEHSP-DDNIIFFKGEED-------DLTPHDKMLRFVDDNGLVP---SSSGTVYDRTTVLIEQDPGTLEDDEDDGQCGEPLPFLVEGE--EGF---LIDQEAMSQGYVQHIISPDQIHLTINPGSTPMPRNIEGATLTLQSECPETKRKEVKRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKAFLTSYSLRIHVRVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHTGKTFNCESQGCSKYFTTLSDLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTFSTQYSLKSHMKGHDNKGTAYSALPQHNGSEDTNHSLYLSELGLLSTDSELQENSSSTQDQDLSTISPAIIFESMFQNSDDPGIQDDPLQTAALIDSFNGDAESVIDVPPPAGNSASLSLPLVLQSGISEPPQPLLPATAPSAPPPAPSLGPGSQPAAFGSPPALLQPPEVPVPHSTQFAANHQEFLPHPQAPPQTIVPGLSVVAGAPASAATVASAVAAPAPPQSTTEPLPAMVQTLPLGANSVLTNNPTITITPTPNTAILQSSLVMGEQNLQWILNGATSSPQNQEQIQQASKVEQVYFATAVPVASGTGSSVQQIGLSVPVIIIKQEEACQCQCACRDSAKER--AAGRRKGCSSPPPPEPNPQPPDGPSLQLPP------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14872-1", "uniprot_id": "MTF1_HUMAN", "id": "Q14872-1", "name": "Metal regulatory transcription factor 1", "aln": "---------------------------MGEHSP-DNNIIYFEAEED-------ELTPDDKMLRFVDKNGLVP---SSSGTVYDRTTVLIEQDPGTLEDEDDDGQCGEHLPFLVGGE--EGFH--LIDHEAMSQGYVQHIISPDQIHLTINPGSTPMPRNIEGATLTLQSECPETKRKEVKRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKAFLTSYSLRIHVRVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHTGKTFNCESEGCSKYFTTLSDLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTFSTQYSLKSHMKGHDNKGHSYNALPQHNGSEDTNHSLCLSDLSLLSTDSELRENSSTTQGQDLSTISPAIIFESMFQNSDDTAIQEDPQQTASLTESFNGDAESVSDVPPSTGNSASLSLPLVLQPGLSEPPQPLLPASAPSAPPPAPSLGPGSQQAAFGNPPALLQPPEVPVPHSTQFAANHQEFLPHPQAP-QPIVPGLSVVAGASASAAAVASAVAAPAPPQSTTEPLPAMVQTLPLGANSVLTNNPTITITPTPNTAILQSSLVMGEQNLQWILNGATSSPQNQEQIQQASKVEKVFFTTAVPVASSPGSSVQQIGLSVPVIIIKQEEACQCQCACRDSAKER--ASSRRKGCSSPPPPEPSPQAPDGPSLQLPAQTFSSAPVPGSSSSTLPSSCEQSRQAETPSDPQTETLSAMDVSEFLSLQSLDTPSNLIPIEALLQGEEEMGLTSSFSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2KFP7-1", "uniprot_id": "A0A0G2KFP7_DANRE", "id": "A0A0G2KFP7-1", "name": "Metal regulatory transcription factor 1", "aln": "MTGASIYRRNKSTHVDTNPGLSFSVRIMGENGPLSETAMLFEDEEEDVDKLGREEEDEDKMANFDKDGNMISGPSSSSGTVYDRTTVLIEQDPIRLDEEGEE----DGMTFLPEGEGDEGSLAFMGDPDGMSQGYIHHTISPDQIQFIINPGSTPMPRNIEGATLTLHSECPETKQREVKRYQCLFEGCTRTYSTAGNLRTHQKTHRGEYTFVCNQQGCGKAFLTSYSLKIHVRVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHTGKTFNCESEGCTKYFTTLSDLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGEKPFFCPSDGCEKTFSSQYSLKSHIRGHD-KGPSFTVS-SHPLSEDANHSLCLSDLSLISTDSELQEN-HNSQGLDLNSVTPIRIFELMFQSPENSVSEDDPKPTESLAESFG------LEPSPQTAPADASTHPAFPQP----PPSTCSSSCSITAPAQDAQTPPTTQQAP---PPAVSSSSQTSSFPSAPPSSSQPAEVSSPSAP----SATQHYMMAQPVSSPSAASVSSVPAG---TAEVTAAVTHTVPLAAP------PTISIAPTLG---LQPSLVMSDQNLQWILSSAASAQQNPE--QQGPKVEKVFFTTAIPVGGNSGNAVQQIGLSLPVIIIKQEESCQCHCACRDSAKDKSTSSSQDKTKNTSPPPPPAPPPPP-PALPKEPPSCCPSKPHTQPQQDLP-------TAPLTPNPPTDALGSMDVSDLLSPETTANIEALLMVADGFSMADGGGSGAP---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:.* .:. : *: **: : .*** .* ....::. ****************** *::: :: : :.** ** ** : * :.*****::* ******:: *******************:*******::******* ****.**************************:************:*********************************************:**:*************************************************:******:*******:*******::*** ** ::.. .* ***:**** **:*.*:******:** .:*. **.:::* *** ***..::. ::** * :* :**. : .* :. : : : * . *. **.. .: : :**. .. * :* *. ***: ...:.. *: ::.: :. *.** . : . ..*:.:.**. :.** *:* .*:.:*:**.* ***:*:** . **.****.:*******..*:*: ** * **..***:*:*:**:**....*.:*******:*********:***:********:: ::.: * .:.*** * * .* *:* . ", "identical_positions": 382, "similar_positions": 164, "identity": "47.87%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020424-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70615-1", "uniprot_id": "LMNB1_RAT", "id": "P70615-1", "name": "Lamin-B1", "aln": "---------------------MATATPVQQ-RAGSRASAPATPFSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKFKAEHDQLLLNYAKKESDLSGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLSAAKKQLADETLLKVDLENRCQSLTEDLEFRKNMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSARGGMMESRMRIESLSSQLSNLQKDSRACLERIQELEDMLAKERDNSRRMLSDKEREMAEIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRG------------------------KRKRVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDT--SVSYKYTSRYVLKAGQTVTVWAANAGVTASPPTDLIWKNQNSWGTGEDVKVVLKNSQGEEVAQRSTVFKTTIPEEEEEEEEEPIGVPLE---EERFHQQGTPRASNKSCAIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14733-1", "uniprot_id": "LMNB1_MOUSE", "id": "P14733-1", "name": "Lamin-B1", "aln": "---------------------MATATPVQQQRAGSRASAPATPLSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKFKAEHDQLLLNYAKKESDLSGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLSAAKKQLADETLLKVDLENRCQSLTEDLEFRKNMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSAREELMESRMRIESLSSQLSNLQKESRACLERIQELEDMLAKERDNSRRMLSDREREMAEIRDQMQQQLSDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRG------------------------KRKRVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDT--SVSYKYTSRYVLKAGQTVTVWAANAGVTASPPTDLIWKNQNSWGTGEDVKVILKNSQGEEVAQRSTVFKTTIPEEEEEEEEEPIGVAVE---EERFHQQGAPRASNKSCAIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20700-1", "uniprot_id": "LMNB1_HUMAN", "id": "P20700-1", "name": "Lamin-B1", "aln": "---------------------MATATPVPP-RMGSRAGGPTTPLSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKCKAEHDQLLLNYAKKESDLNGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLAAAKKQLADETLLKVDLENRCQSLTEDLEFRKSMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSAREELMESRMRIESLSSQLSNLQKESRACLERIQELEDLLAKEKDNSRRMLTDKEREMAEIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRG------------------------KRKRVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDT--SVSYKYTSRYVLKAGQTVTIWAANAGVTASPPTDLIWKNQNSWGTGEDVKVILKNSQGEEVAQRSTVFKTTIPEEEEEEEE-AAGVVVE---EELFHQQGTPRASNRSCAIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QHC4-1", "uniprot_id": "F1QHC4_DANRE", "id": "F1QHC4-1", "name": "", "aln": "---------------------MASAACTPAGQQSLSRGTSSTPLSPARISRLQEKEELQQLNDRLAAYIDTVRSLESENSVLQIQIREREDVRNRELTGLRTLYETELADARKALDDTARERARLQIELGKIKSEQEQLQHTYAKKDADLTSSQNRLKDVEALLNAKEAALNTAVSERKTLENTLSDLQIRVQELEGGLISAKKQLSDETLLRVDLENRCQSLMEELEFRKNMFEEEIKDTRRRHETRLVEVDSGRQMEYEFKLAQALTDMRQQHDEQVKLYKEEMEQTYVSKLENIRLSSEMNSSSASMAREELRESTLRVESLAGQLANLQKEARAWQDRINELEGALSHEKDLSRRLLAEKEREIAEIRAKMQQQLDEYEQLLDVKLALDMEINAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRG------------------------KRKRVDVEESEASSSVSIAHSASATGNVSIDELDVDGKFIRLHNNSEQDQPMAGFQLTRTIGEV--TATYKFTAKYNLKAGQKVTIWASNAGISSNPPADLIWKNQPSWGTGENIKVALLSPAGEEVAVRSTVFKTAVEDEDDDEEEEKEAEVIE---EHFYHQQGDPRAAKRGCLIM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08928-1", "uniprot_id": "LMNB_DROME", "id": "P08928-1", "name": "Lamin", "aln": "MSSKSRRAGTATPQPGNTSTPRPPSAGPQPPPPSTHSQTASSPLSPTRHSRVAEKVELQNLNDRLATYIDRVRNLETENSRLTIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDDTARDRARAEIDIKRLWEENEELKNKLDKKTKECTTAEGNVRMYESRANELNNKYNQANADRKKLNEDLNEALKELERLRKQFEETRKNLEQETLSRVDLENTIQSLREELSFKDQIHSQEINESRRIKQTEYSEIDGRLSSEYDAKLKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEAAARTSNSTHKSIEELRSTRVRIDALNANINELEQANADLNARIRDLERQLDNDRERHGQEIDLLEKELIRLREEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLVGEEARLNITP---ATNTATVQSFSQSLRNST-----RATPSRR---TP----SAAVKRKRAVVDESEDHSVADYYVSASAKGNVEIKEIDPEGKFVRLFNKGSEEVAIGGWQLQRLINEKGPSTTYKFHRSVRIEPNGVITVWSADTKASHEPPSSLVMKS-QKWVSADNTRTILLNSEGEAVANLDRIKRIVSQHTSSSRLSRRRSVTAVDGNEQLYHQQGDPQQSNEKCAIM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03427-1", "uniprot_id": "LMNA_DROME", "id": "Q03427-1", "name": "Lamin-C", "aln": "MSARR--------VTLNTRVSRASTSTPVGGASTSSRVGATSPTSPTRTSRQQEKEELQHLNDRLACYIDRMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKLLDETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLADRKKFEDQAKELALENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTETRSRRQIEISEIDGRLSRQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAAQGSALATEEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAELQRMRDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRLNIESPGRPTTDSGISSNGSHLTASASSRSGRVTPSGRRSATPGISGSSAVKRRRTVIDESEDRTLSEYSVNAAAKGDLEIIEADVEGRFIKLHNKGTEEINLTGWQLTRIAGDE--ELAFKFSRGSKVLGGASVTIWSVDAGTAHDPPNNLVMK--KKWPVANSMRSVLANADKEDVASYDRVRANVSSHTSRHRSSGTPSTGFTLGSG-----AGSTGVRSLFSLLF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..:: .::* **:* ** ** **:.****** *** :*.**.*** * :: .:. ** :.:: ::* ** :*: **:**:::*: :*:: : *:::* ** : . :: . : * * : : .::*.:: .: . .*. : :*:* *** :***** *** *:* *:..:. :*:.::* :: . *:*. . :*: ** *:* ::* *:: *::: ::*:: * :::. : :: :. : : :::.* .:: :*:. **.:** * ::: : : * *: .:* :* :**.:*: *:*:*::**:** ** *** *** **:: . . * . : : **:*. ::*** : . .*:*.*:: * * * :*:*::* *.. :: : *::: * .: ::*: : . :*:*: :: : .** .*: * .* .:. : * .. * ** . : . . . . . . * . . . ::", "identical_positions": 139, "similar_positions": 199, "identity": "21.79%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020426-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52732-1", "uniprot_id": "KIF11_HUMAN", "id": "P52732-1", "name": "Kinesin-like protein KIF11", "aln": "MASQPNSSAKKKEEKGKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQEEQIVELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEYITSALESTEEKLHDAASKLLNTVEETTKDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHVSQIFNMILKEQSLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSILKINSQLKHIFKTSLTVADKIEDQKKELDGFLSILCNNLHELQENTICSLVESQKQCGNLTEDLKTIKQTHSQELCKLMNLWTERFCALEEKCEN-----------IQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFSQELRNFNQEGTKLVEESVKHSDKLNGNLEKISQETEQRCESLNTRTVYFSEQWVSSLNEREQELHNLLEVVSQCCEASSSDITEKSDGRKAAHEKQHNIFLDQMTIDEDKLIAQNLELNETIKIGLTKLNCFLEQDLKLDIPTGTTPQRKSYLYPSTLVRTEPREHLLDQLKRKQPELLMMLNCSE---NNKEETIPDVDVEEAVLGQYTEEPLSQEPSVDAGVDCSSIGGVPFFQHKKSHGKDKENRGINTLERSKVEETTEHLVTKSRLPLRAQINL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QK82-1", "uniprot_id": "F1QK82_DANRE", "id": "F1QK82-1", "name": "", "aln": "MASSQVPAAKK-DEKGRNIQVVVRCRPFNTVERKSGSHTVVECDQNRKEVIMRTGGATDKAARKTYTFDMVFGPSAKQIEVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGDRSPNEEFTWEEDPLAGIIPRTLHQIFEKLSNNGTEFSVKVSLLEIYNEELFDLLSPAPDVTERLQLFDDPRNKRGVTIKGLEEITVHNKNEVYQILERGAAKRKTASTLMNAYSSRSHSVFSVTIHMKEITLDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVIKALVERGPHVPYRESKLTRILQDSLGGRTKTSIIATVSPASINLEETLSTLDYANRAKSIMNKPEVNQKLTKRTLIKEYTEEIERLKRDLAATRDKHGVYLSVDNYETLNGKIVSQEEQITEYTERIAAMEEELKKIIDLFTDSKQKLEQCTEDLQDKNQRLEEAHKDLSETRHRLNQEEFISTQLQTNESHLYNTADQLLSTAEASTQDVGGLHAKLQRKKDVELHNSKVQESFSQCMENCYNSMQTSLKEQSQKHAAMIDYYRSSVGELLNTNGKVFKETLSAVCESYSSIKGAVGEGVERCKEQVLNQEKLSQDAQNSILEILDEHKQHLEEVLVAQAVPGIRSVMSMNDNLKQTLHKYHNLAEQMQGVKADMMTFFDAYTESLASMRECALQGFNTLRAEHDKLKQQISQAGNSHQVRVAELVQCLQNQMNLLAVDTQNDFEGLSQAASAQIPPLETLQSSIESKCTVAEEQAVSVRARLGSSVHGVISEMNSVTKEGERALEECAGYCGHLQTSLDSLAESGLKWCDEAKGLTESKAQEQLKLIRQTDTAVQDLLKSVEEKGEKAVQDCEARLGQMQQEMEATLGRVEMQTSKDEATLQEHRETLSSINTQALDTVHNFISSELRQDLPTGTTPQRKEYMYPRVLSRPRSREELEEEFRAQQEQLQSELKPCEIVMEVEEEKPVDQDSLEDDVSVSSDGNNTEQSCSDENLICYENGRIPFFKKKS----KKEN-GSKSLNRSKVENDSMSTPPRSKLPLRCQN--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***. .:*** :***:************ .***:.:*::**** **** :**** :**::***********.*:***:*************************************:******:**********************::***********************.*:.**:****:********** ************:*******:*****.**:********************** *:*************************************************.***** **********************:******:****:*********:**:***.*:***********::******************:*:*:***:* :*:..:.**:. *****.* *:*.*:****::: :** *.*::*:**..***:*.*.** ::*.*.**: :* :**:*:: *::.*.:*:::*.:**.*.* :*:**.***:**:*** *: **::.*: *.: ::. :*.*: :*: *.*: **:: ::: .*:**.:. ..:. :.. * :** *. *.: : :*:::.*: :::. : *::: * .* . * * : *::.:*.:**: ::. .:*::::. * :: *:. :.* .::* :: .: : : .:*.:::. ::*. .:.:*:: ::: * . :* **.::*..*:.*.. :: . :: :. .*. .*:....:** : :**.. :..:*: .*:.:::. : *:. : * ::: :. :.: : :::**: *.: * : .* : . : * . . * : ** .* :. *.. . .* .:: *:..:*: *:*********.*:** .* *...**.* :::: :* :* *: .* : :**. * * * :. :: :::.. * .: * . * :***::*. .*** * ::*:*****: : .:*:****.* ", "identical_positions": 521, "similar_positions": 335, "identity": "48.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020430-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1E1-1", "uniprot_id": "FLOT1_RAT", "id": "Q9Z1E1-1", "name": "Flotillin-1", "aln": "---MFFTCGPNEAMVVSGFCRSPPVMVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHGVPISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEIYKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGEAEAKRDAGIREAKAKQEKVSAQCLSEIEMAKAQRDYELKKATYDIEVNTRRAQADLAYQLQVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYRLERLAEAEKAQLIMQAEAEAESVRMRGEAEAFAVGARARAEAEQMAKKAEAFQMYQEAAQLDMLLEKLPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDILSRLPESVERLTGVSISQVNHNKPLRTA----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08917-1", "uniprot_id": "FLOT1_MOUSE", "id": "O08917-1", "name": "Flotillin-1", "aln": "---MFFTCGPNEAMVVSGFCRSPPVMVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHGVPISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEIYKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGEAEAKRDAGIREAKAKQEKVSAQCLSEIEMAKAQRDYELKKATYDIEVNTRRAQADLAYQLQVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYRLERLAEAEKAQLIMQAEAEAESVRMRGEAEAFAIGARARAEAEQMAKKAEAFQMYQEAAQLDMLLEKLPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDILSRLPESVERLTGVSISQVNHNKPLRTA----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75955-1", "uniprot_id": "FLOT1_HUMAN", "id": "O75955-1", "name": "Flotillin-1", "aln": "---MFFTCGPNEAMVVSGFCRSPPVMVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHGVPISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEIYKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGEAEAKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADLAYQLQVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYKLERLAEAEKSQLIMQAEAEAASVRMRGEAEAFAIGARARAEAEQMAKKAEAFQLYQEAAQLDMLLEKLPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDILTRLPESVERLTGVSISQVNH-KPLRTA----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZZ76-1", "uniprot_id": "Q7ZZ76_DANRE", "id": "Q7ZZ76-1", "name": "Flotillin", "aln": "---MFYTCGPNEAMVVSGFCRSPPVMISGGRVFVFPCVQQIQRISLNTLTLNVKSDKVYTRHGVPISVTGIAQMKIQGQNKQMLAAACQMFLGKSDSEIAHIALETLEGHQRAIIAHLTVEEIYKDRKKFSEQVFKVASSDLVNMGISVVSYTLKDVHDDQDYLHSLGKARTAQVQKDARIGEAKNKRDAVIREAHAMQEKVSAQYMNEIEMAKAQRDYELKKAIYDIEVFTKKAESEMAYQLQVAKTKQRIEEEKMQVLVVERSQQITLQEQEISRKEKELEAKVKKPAEAERYRLEKLAEAERLQLIMEAEAEAESIRVRGEAEAYAVEAKGRAEAEQMAKKAEAFQHYKEGAMVDMLLEKLPMMADEISKPLSATNKVTMVSSGGSEIGAAKLTGEVLDIMTKLPETIEKLTGVNISQCIEIKTSREESCSLYFVMQS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O61491-1", "uniprot_id": "FLOT1_DROME", "id": "O61491-1", "name": "Flotillin-1", "aln": "MTWGFVTCGPNEALVVSGCCYMKPLLVPGGRAFVWPVGQQVQRISLNTMTLQVESPCVYTSQGVPISVTGIAQVKVQGQNEDMLLTACEQFLGKSEAEINHIALVTLEGHQRAIMGSMTVEEIYKDRKKFSKQVFEVASSDLANMGITVVSYTIKDLRDEEGYLRSLGMARTAEVKRDARIGEAEARAEAHIKEAIAEEQRMAARFLNDTDIAKAQRDFELKKAAYDVEVQTKKAEAEMAYELQAAKTKQRIKEEQMQVKVIERTQEIAVQEQEIMRRERELEATIRRPAEAEKFRMEKLAEANKQRVVMEAEAEAESIRIRGEAEAFAIAAKAKAEAEQMAMKAEAYREYREAAMVEMLLDTLPKVAAEVAAPLSQAKKITMVSSGTGDIGAAKLTGEVLSIVNKVPELVKNITGVDIARSVHAG---------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *******:**** * *:::.***.** * **:*******:**:*:* *** :***********:*:****::** :**: ****:::** **** *********:. :*********:***:***:******.****:*****:**::*::.**:*** ****:*::*******: : :* *:** * :::::*: :.: ::******:***** **:** *::*::::**:**.*****:*:*:::** *:**:*::::***** *:*:**** :::*****::::*:****:: :::*:***** *:*:******:*: *:.:******* ****:: *:*.* ::***:.** :* *:: **: ::*:*:**** . :****:*****.*:.::** ::.:***.*:: . ", "identical_positions": 247, "similar_positions": 129, "identity": "56.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020430-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2S9-1", "uniprot_id": "FLOT2_RAT", "id": "Q9Z2S9-1", "name": "Flotillin-2", "aln": "MGNCHTVGPNEALVVSGGCCGSDYKQYVFGGWAWAWWCISDTQRISLEIMTLQPRCEDVETAEGVALTVTGVAQVKIMTEK-------------ELLAVACEQFLGKNVQDIKNVVLQTLEGHLRSILGTLTVEQIYQDRDQFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDADIGVAEAERDAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSAFSEEVNIKTAEAQLAYELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQEILRTDKELIATVRRPAEAEAHRIQQIAEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMALVLEALPQIAAKISAPLTKVDEIVVLSGDNSKVTSEVNRLLAELPASVHALTGVDLSKIPLIKNATGAQV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60634-1", "uniprot_id": "FLOT2_MOUSE", "id": "Q60634-1", "name": "Flotillin-2", "aln": "MGNCHTVGPNEALVVSGGCCGSDYKQYVFGGWAWAWWCISDTQRISLEIMTLQPRCEDVETAEGVALTVTGVAQVKIMTEK-------------ELLAVACEQFLGKNVQDIKNVVLQTLEGHLRSILGTLTVEQIYQDRDQFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDADIGVAEAERDAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSAFSEEVNIKTAEAQLAYELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQEILRTDKELIATVRRPAEAEAHRIQQIAEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMALVLEALPQIAAKISAPLTKVDEIVVLSGDNSKVTSEVNRLLAELPASVHALTGVDLSKIPLIKNATGAQV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14254-1", "uniprot_id": "FLOT2_HUMAN", "id": "Q14254-1", "name": "Flotillin-2", "aln": "MGNCHTVGPNEALVVSGGCCGSDYKQYVFGGWAWAWWCISDTQRISLEIMTLQPRCEDVETAEGVALTVTGVAQVKIMTEK-------------ELLAVACEQFLGKNVQDIKNVVLQTLEGHLRSILGTLTVEQIYQDRDQFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDADIGVAEAERDAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSAFSEEVNIKTAEAQLAYELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQEILRTDKELIATVRRPAEAEAHRIQQIAEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMALVLEALPQIAAKIAAPLTKVDEIVVLSGDNSKVTSEVNRLLAELPASVHALTGVDLSKIPLIKKATGVQV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q98TZ8-1", "uniprot_id": "FLOT2_DANRE", "id": "Q98TZ8-1", "name": "Flotillin-2a", "aln": "MGNCYTVGPNEALVVSGGCCGSDGKTYTVGGWAWAWWLITDIQKITLEIMTLQPKCEDVETAEGVAITVTGVAQVKVMTDN-------------ELLGYACEQFLGKTVTEIKSVILQTLEGHLRSILGTLTVEQIYQDRDQFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGKSQTAAVQRDADIGVAEAERDAGIREAECKKEMMDIKFQADTKMADSKRELEMQKAAFNQEVNTKKAEAQLAYELQAAKEQQKIRLEEIEIEVVQRKKQISIEEKEILRTDKELIATVRRPAEAEAFKMEQLAEAKKIKKVLTAQAEAEKIKRIGEAEAGSIEAVGKAEAEKMRLKAEAYQQYGEAAKTALVLEALPKIAGKVAAPLGRTNEIVILSGDGGRVTGEVNRLLAELPVSVNALTGVDLSKIPLLQKMTNPQA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O61492-1", "uniprot_id": "FLOT2_DROME", "id": "O61492-1", "name": "Flotillin-2", "aln": "MGNIHTTGPNEALIVSGGCCGSTKKRTIVGGWAWAWWLVTDVQRLSLNVMTLNPMCENVETSQGVPLTVTGVAQCKIMKSSSYKQTDYHNDEADELLGTASEQFLGKSVKEIKQTILQTLEGHLRAILGTLTVEEVYKDRDQFAALVREVAAPDVGRMGIEILSFTIKDVYDDVQYLASLGKAQTAVVKRDADAGVAEANRDAGIREAECEKSAMDVKYSTDTKIEDNTRMYKLQKANFDQEINTAKAESQLAYELQAAKIRQRIRNEEIQIEVVERRKQIEIESQEVQRKDRELTGTVKLPAEAEAFRLQTLAQAKQCQTIEGARAEAERIRKIGSAEAHAIELVGKAEAERMRMKAHVYKQYGDAAIMNIVLESLPKIAAEVAAPLAKTDEIVLIGG-NDNITNDVTRLVAQLPPSINALTGVDLSKV--LSKIPGAKA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** :*.******:******** * .******** ::* *:::*::***:* **:***::**.:******* *:*... ***. *.******.* :**..:*********:********::*:****** ***************************.*:**:****:***.*:**** *****:**********:*. :*:*: :***: *..* ::**: *.:*:* .**:*******.*: :*:** ***:****:*:*** :* :*: *.*:** .**: ******.::: :*:.:: : : *:****:*::**.*** ** :******:*::**..*::**:** :***:**:**.:::*** :.:***::.* ...:*.:*.**:*:** *::*********: :.: .. :.", "identical_positions": 254, "similar_positions": 127, "identity": "57.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020503-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24062-1", "uniprot_id": "IGF1R_RAT", "id": "P24062-1", "name": "Insulin-like growth factor 1 receptor", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKSGSGGGSPTSLWGLVFLSAALS---LWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGFLHILLIS------KAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTIDWSLILDAVSNNYIVGNKPPKE---CGDLCPGTLEEKPMCEKTTIN---------NEYNYRCWTTNRCQKMCPSVCGKRACTENNECCHPECLGSCHTPDD-NTTCVACRHYYYKGVCVPACPPGTYRFEGWRCVDRDFCANIPNAESSDSDGFVIHDGECMQECPSGFIRNSTQSMYCIPCEGPCPKVCGDEEKKTKTIDSVTSAQMLQGCTILKG----NLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEG-NYSFYVLDNQNLQQLWDWNHRNLTVRSGKMYFAFNPKLCVSEIYRMEEVTGTKGRQS-KGDINTRNNGERASCESDVLRFTSTTTWKNRIIITWHRYRPPD--YRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKEGEPG----ILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPTLPNGNLSYYIVRWQRQPQDGYLFRHNYCSKD-KIPIRKYADGTIDVEEVTENPKTEVCGGDKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRP--------------------------------ERRRR------DVLQVANTTMSS-RSRNTTVADTYNITDPEEFETEYP-----------FFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPG-----------PVTWE--PRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQR---ECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVP-AKTTYENFMHLIIALPVAILLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEV-----------ENN-LVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIIGSIKDEMEPS-FQEVSFYYSEE------------NKPPEPEELEMELELEPENMESVPLDPS-------------ASSASLPLP-------------------------------------------------------------------------------------------------------------------------------ERHSGHKAENGP--GVLVLRASFDERQPYAHMNGGRANERALPLPQSSTC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60751-1", "uniprot_id": "IGF1R_MOUSE", "id": "Q60751-1", "name": "Insulin-like growth factor 1 receptor", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKSGSGGGSPTSLWGLVFLSAALS---LWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGFLHILLIS------KAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTIDWSLILDAVSNNYIVGNKPPKE---CGDLCPGTLEEKPMCEKTTIN---------NEYNYRCWTTNRCQKMCPSVCGKRACTENNECCHPECLGSCHTPDD-NTTCVACRHYYYKGVCVPACPPGTYRFEGWRCVDRDFCANIPNAESSDSDGFVIHDDECMQECPSGFIRNSTQSMYCIPCEGPCPKVCGDEEKKTKTIDSVTSAQMLQGCTILKG----NLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEG-NYSFYVLDNQNLQQLWDWNHRNLTVRSGKMYFAFNPKLCVSEIYRMEEVTGTKGRQS-KGDINTRNNGERASCESDVLRFTSTTTWKNRIIITWHRYRPPD--YRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKEGEPG----ILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPTLPNGNLSYYIVRWQRQPQDGYLYRHNYCSKD-KIPIRKYADGTIDVEEVTENPKTEVCGGDKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRP--------------------------------ERRRR------DVMQVANTTMSS-RSRNTTVADTYNITDPEEFETEYP-----------FFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPG-----------PVTWE--PRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQR---ECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVP-AKTTYENFMHLIIALPVAILLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEV-----------EQNNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIIGSIKDEMEPS-FQEVSFYYSEE------------NKPPEPEELEMELEMEPENMESVPLDPS-------------ASSASLPLP-------------------------------------------------------------------------------------------------------------------------------ERHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRANERALPLPQSSTC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08069-1", "uniprot_id": "IGF1R_HUMAN", "id": "P08069-1", "name": "Insulin-like growth factor 1 receptor", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKSGSGGGSPTSLWGLLFLSAALS---LWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLIS------KAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKE---CGDLCPGTMEEKPMCEKTTIN---------NEYNYRCWTTNRCQKMCPSTCGKRACTENNECCHPECLGSCSAPDN-DTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPKVCE-EEKKTKTIDSVTSAQMLQGCTIFKG----NLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEG-NYSFYVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQS-KGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPD--YRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKDVEPG----ILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRHNYCSKD-KIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRP--------------------------------ERKRR------DVMQVANTTMSS-RSRNTTAADTYNITDPEELETEYP-----------FFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPG-----------PVTWE--PRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQR---ECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQ-AKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEM-----------ENN-PVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPG-FREVSFYYSEE------------NKLPEPE----ELDLEPENMESVPLDPS-------------ASSSSLPLP-------------------------------------------------------------------------------------------------------------------------------DRHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HSB5-1", "uniprot_id": "A0AC58HSB5_DANRE", "id": "A0AC58HSB5-1", "name": "Tyrosine-protein kinase receptor", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFPLKENSVIITRDILSTPSSPPVIFTGMRSGTARDVWTLFWGPALFLSTIC---LWCARGEVCGPHIDIRNDITEFKKLENCTVVEGYLQILLIGDKNNNLNQEHFRTLSFPKLTMVTDYILLFRVSGLDSLSVLFPNLNVIRGRNLFYNYALVIFEMTSLKDIGLYNLRNITRGAIRIEKNPELCYLDSVDWSLLMDAEFNNYIAGNKQSKE---CGDVCPGINEDRPHCIRTSFN---------DNYSYRCWTSNHCQKVCPKECEKRACTDAGQCCHPQCLGSCTEADN-DKACAACQHYFHEDRCVEACPPDTYKFEGWRCITMEMCARVHLPSEVD---FVIHNGECMPDCPPGFTRNETQSMFCSACDGLCDKVCE-----SKTIDSVDAAQSLQGCTVIKG----NLQINIRRGNNIASELESFMGLIQTVTGYVRIKHTHTLGSLSFLKSLRYIVGEELVDN-TYAFHAVDNHNLQYLWDWTQHNLTIKTGKLYFRFNPKLCMSEIRKMWEKTSVREKMA-EDDV--RSNGERASCESYILKFRSNHTQSTRIKLTWERYRPPD--YRDLISFIVYYKEAPFQNITEFDGQDGCGSNSWNMVDVDLPQEKSIDPG----VLLSPLKPWTQYAIFVKAVTL-VVEDKHVGGAKSEVVYIRTNASAPSMPLDARAYANSSSSLMVKWSPPIAPNGNKTFYFLRWQQQAEDGELYQHNYCSKELKIPIRISATSLSDMEGETKPTKSDVAGGEKG-CCPCPKTKEDLKAEAEDRSYRKVFENFLHNSIFTPRPP-------------------------------DRKRR------DLMGVANSTLVSGVSRNISVLES-NITQPELPEKEYP-----------FSEGKVHT-EFMEIHNLRPFTVYRIDIHACNYEVHR--CSAAAFVFSRTKPADKADDIPG-----------SVTQERDEKGEGIVLLRWPEPLHPNGLILMYEIKYRLGTEAEKH--ECVSRQQYKVLRGAQLSNLASGNYSARVRATSLAGNGSWTEPVSFYVPPPKRNYDNAFYVAIIIPVIVLLLLLFVIVAVIIVTKKRNSDRIGNGVLYASVNPEYFSPFEMYVPDEWEVAREKITMCRELGQGSFGMVYEGIAKGVVKDEPETRVAIKTVNESASVRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRSKE-----------QGSSSQSLPP-LKKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTNSDVWSFGVVLWEIATLAEQPYQGMSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIINSIKEELEPP-FREVSFFYSEE------------NKPPDTE----ELDMEVENMENVPLDPASTLAPSSQGNTGIQSQSPQPLSPAQGPGTPLGSAQ-------------------------------------------------------------------------------------------------TPSTSPPSSSASPGLALDKHSGQVAANGP---VVLLGPAFDETQPYAHMNGGRKNERALPLPQSSAC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09208-1", "uniprot_id": "INSR_DROME", "id": "P09208-1", "name": "Insulin-like receptor", "aln": "MFNMPRGVTKSKSKRGKIKMENDMAAAATTTACTLGHICVLCRQEMLLDTCCCRQAVEAVDSPASSEEAYSSSNSSSCQASSEISAEEVWFLSHDDIVLCRRPKFDEVETTGKKRDVKCSGHQCSNECDDGSTKNNRQQRENFNIFSNCHNILRTLQSLLLLMFNCGIFNKRRRRQHQQQHHHHYQHHHQQHHQQHHQRQQANVSYTKFLLLLQTLAAATTRLSLSPKNYKQQQQLQHNQQLPRATPQQKQQEKDRHKCFHYKHNYSYSPGISLLLFILLANTLAIQAVVLPAHQQHLLHNDIADGLDKTALSVSGTQSRWTRSESNPTMRLSQNVKPCKSMDIRNMVSHFNQLENCTVIEGFLLIDLIN-------DASPLNRSFPKLTEVTDYIIIYRVTGLHSLSKIFPNLSVIRGNKLFDGYALVVYSNFDLMDLGLHKLRSITRGGVRIEKNHKLCYDRTIDWLEILAENETQLVVLTENGKEKECRLSKCPGEIRIEEGHDTTAIEGELNASCQLHNNRRLCWNSKLCQTKCPEKCRN-NCIDEHTCCSQDCLGGCVIDKNGNESCISCRNVSFNNICMDSCPKGYYQFD-SRCVTANECITLTKFETNSVYSGIPYNGQCITHCPTGYQKSENKRMCEPCPGGKCDKECS-----SGLIDSLERAREFHGCTIITGTEPLTISIKRESGAHVMDELKYGLAAVHKIQSSLMVHLTYGLKSLKFFQSLTEISGDPPMDADKYALYVLDNRDLDELWGPNQ-TVFIRKGGVFFHFNPKLCVSTINQLLPMLASKPKFFEKSDVGADSNGNRGSCGTAVLNVTLQSVGANSAMLNVTTKVEIGEPQKPSNATIVFKDPRAFIGFVFYHMIDPYGNSTKSSDDPCDDRWKVSSPEKSGVMVLSNLIPYTNYSYYVR----TMAISSELTNAESDVKNFRTNPGRPSKVTEVVATAISDSKINVTWSYLDKPYGVLTRYFIKAKLINRPTRNNNRDYCTEP------LVKAMENDLPATTPTKKISDPLAGDCKCVEGSKKTSSQEYDDRKVQAGMEFENALQNFIFVPNIRKSKNGSSDKSDGAEGAALDSNAIPNGGATNPSRRRRDVALEPELDDVEGSVLLRHVRSITDDTDAFFEKDDENTYKDEEDLSSNKQFYEVFAKELPPNQTHFVFEKLRHFTRYAIFVVACREEIPSEKLRDTSFKKSLCSDYDTVFQTTKRKKFADIVMDLKVDLEHANNTESPVRVRWTPPVDPNGEIVTYEVAYKLQKPDQVEEKKCIPAADFNQTAG-YLIKLNEGLYSFRVRANSIAGYGDFTEVEHIKVE-PPPSYAKVFFWLLGIGLAFLIVSLFGYVCYLHKRKVPSND------LHMNTEVNPFYASMQYIPDDWEVLRENIIQLAPLGQGSFGMVYEGILKSFPPNGVDRECAIKTVNENATDRERTNFLSEASVMKEFDTYHVVRLLGVCSRGQPALVVMELMKKGDLKSYLRAHRPEERDEAMMTYLNRIGVTGNVQPPTYGRIYQMAIEIADGMAYLAAKKFVHRDLAARNCMVADDLTVKIGDFGMTRDIYETDYYRKGTKGLLPVRWMPPESLRDGVYSSASDVFSFGVVLWEMATLAAQPYQGLSNEQVLRYVIDGGVMERPENCPDFLHKLMQRCWHHRSSARPSFLDIIAYLEPQCPNSQFKEVSFYHSEAGLQHREKERKERNQLDAFAAVPLDQDLQDREQQEDATTPLRMGDYQQNSSLDQPPESPIAMVDDQGSHLPFSLPSGFIASSTPDGQTVMATAFQNIPAAQGDISATYVVPDADALDGDRGYEIYDPSPKCAELPTSRSGSTGGGKLSGEQHLLPRKGRQPTIMSSSMPDDVIGGSSLQPSTASAGSSNASSHTGRPSLKKTVADSVRNKANFINRHLFNHKRTGSNASHKSNASNAPSTSSNTNLTSHPVAMGNLGTIESGGSGSAGSYTGTPRFYTPSATPGGGSGMAISDNPNYRLLDESIASEQATILTTSSPNPNYEMMHPPTSLVSTNPNYMPMNETPVQMAGVTISHNPNYQPMQAPLNARQSQSSSDEDNEQEEDDEDEDDDVDDEHVEHIKMERMPLSRPRQRALPSKTQPPRSRSVSQTRKSPTNPNSGIGATGAGNRSNLLKENWLRPASTPRPPPPNGFIGREA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* : : . : : . :**** .:::******:**:* * **. . ***** :*:*::::**:**.**. :****.**** :** .****::. .* *:**::**.****.:***** .*** ::** :: .: :. .: ** . *** . . *::: .: **.:: **. **. * : * : ** :***.* .: : :* :*:: . . *: :** . *:*: **: : * : . . : ::.:*: .**.*: :. .: * * * * * : ***: *: ::***::.* .: *: . * :: .**: :. :. : . : :: :: * **.*::.* * *: :: .*:::.:**::*: **. : .: :: * ::* ******:* * :: . : : :.*: .**:*.** : :*.. . . :. . : : *: . .* ... :. * *..: . * * .* ::* * *:*:*: :*: :. ...: .*:*:: :***.. ** :. : : *.*.: *.*. * * : *::: : . .::**:: *: * * . . . * .*. . : : .. . *** *:* **.*. .*:** :: * .:.: :: .: * .: * : . : :** ** * * : :*. * : * : : . : . * * . *. : ::*. * .*** *: **: * : :*:. ::. * * .* * *: *::*.*::* *.:*: : * . * : :. : : : .*:: : : ... *: ..: : * . *:**:*** **:* ************: *.. : : . ******* *: *** :**.********: :******** *:***:**:****.:*****:**: *.: ** :: *** ********* *:***************:*:********************** *********.****:***::: ***:********:**** *****:*******:*::**::::*:****:*.:**: **::... *****:** :: : *:****::** *: : ::: .: :. . * ..:. .: . *:*: : : . : . * : : : * . * .: .::.: ", "identical_positions": 430, "similar_positions": 412, "identity": "19.75%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020503-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24062-1", "uniprot_id": "IGF1R_RAT", "id": "P24062-1", "name": "Insulin-like growth factor 1 receptor", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKSGSGGGSPTSLWGLVFLSAALSLWPTSGEICG----------------------------------------------------------------------------------------------------------------PGIDIRNDYQQLKRLENCTVIEGFLHILLIS-----KAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTIDWSLILDAVSNNYIVGNKPPKE---CGDLCPGTLEEKPMCEKTTINNEYNY---------RCWTTNRCQKMCPSVCGKRACTENNECCHPECLGSCHTPDD-NTTCVACRHYYYKGVCVPACPPGTYRFEGWRCVDRDFCANIPNAESSDSDGFVIHDGECMQECPSGFIRNSTQ----SMYCIPCEG-PCPKVCGDEEKKTKTIDSVTSAQMLQGCTILKG--NLLINIRR--GNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEG-NYSFYVLDNQNLQQLWDWNHRNLTVRSGKMYFAFNPKLCVSEIYRMEEVTGTKGRQS-KGDINTRNNGERASCESDVLRFTSTTTWKNRIIITWHRYRPPD--YRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKEGEPG----ILLHGLKPWTQYAVYVKAVTLTMVENDHIR-----GAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPTLPNGNLSYYIVRWQRQPQDGYLFRHNYCSKD-KIPIRKYADGTIDVEEVTENPKTEVCGGDKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRP--------------------------------ERRRR---------DVLQVANTT-MSSRSRNTTVADTYN----ITDPEEFETEYPFFESRVDNKE----RTVISNLRPFTLYRIDIHSCNHEAEK----------LGCSASNFVFARTMP---AEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVE---DQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVPAKTTYENFMHLIIALPVAILLIVGGLVIMLYVFHRK-RNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEVENN------------LVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIIGSIKDEMEPS-FQEVSFYYSEE------------NKPPEPEELEMELELEPE-------------------NMESVPLDPS-------------------ASSAS------------------------------------------------------------------------------------------------LPLPERHSGHKAENGP--------GVLVLRASFDERQPYAHMNGG-----RANERALPLPQSSTC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60751-1", "uniprot_id": "IGF1R_MOUSE", "id": "Q60751-1", "name": "Insulin-like growth factor 1 receptor", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKSGSGGGSPTSLWGLVFLSAALSLWPTSGEICG----------------------------------------------------------------------------------------------------------------PGIDIRNDYQQLKRLENCTVIEGFLHILLIS-----KAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTIDWSLILDAVSNNYIVGNKPPKE---CGDLCPGTLEEKPMCEKTTINNEYNY---------RCWTTNRCQKMCPSVCGKRACTENNECCHPECLGSCHTPDD-NTTCVACRHYYYKGVCVPACPPGTYRFEGWRCVDRDFCANIPNAESSDSDGFVIHDDECMQECPSGFIRNSTQ----SMYCIPCEG-PCPKVCGDEEKKTKTIDSVTSAQMLQGCTILKG--NLLINIRR--GNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEG-NYSFYVLDNQNLQQLWDWNHRNLTVRSGKMYFAFNPKLCVSEIYRMEEVTGTKGRQS-KGDINTRNNGERASCESDVLRFTSTTTWKNRIIITWHRYRPPD--YRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKEGEPG----ILLHGLKPWTQYAVYVKAVTLTMVENDHIR-----GAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPTLPNGNLSYYIVRWQRQPQDGYLYRHNYCSKD-KIPIRKYADGTIDVEEVTENPKTEVCGGDKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRP--------------------------------ERRRR---------DVMQVANTT-MSSRSRNTTVADTYN----ITDPEEFETEYPFFESRVDNKE----RTVISNLRPFTLYRIDIHSCNHEAEK----------LGCSASNFVFARTMP---AEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVE---DQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVPAKTTYENFMHLIIALPVAILLIVGGLVIMLYVFHRK-RNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEVEQNN-----------LVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIIGSIKDEMEPS-FQEVSFYYSEE------------NKPPEPEELEMELEMEPE-------------------NMESVPLDPS-------------------ASSAS------------------------------------------------------------------------------------------------LPLPERHSGHKAENGPGP------GVLVLRASFDERQPYAHMNGG-----RANERALPLPQSSTC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08069-1", "uniprot_id": "IGF1R_HUMAN", "id": "P08069-1", "name": "Insulin-like growth factor 1 receptor", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICG----------------------------------------------------------------------------------------------------------------PGIDIRNDYQQLKRLENCTVIEGYLHILLIS-----KAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKE---CGDLCPGTMEEKPMCEKTTINNEYNY---------RCWTTNRCQKMCPSTCGKRACTENNECCHPECLGSCSAPDN-DTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHDGECMQECPSGFIRNGSQ----SMYCIPCEG-PCPKVCE-EEKKTKTIDSVTSAQMLQGCTIFKG--NLLINIRR--GNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEG-NYSFYVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQS-KGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPD--YRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKDVEPG----ILLHGLKPWTQYAVYVKAVTLTMVENDHIR-----GAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRHNYCSKD-KIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRP--------------------------------ERKRR---------DVMQVANTT-MSSRSRNTTAADTYN----ITDPEELETEYPFFESRVDNKE----RTVISNLRPFTLYRIDIHSCNHEAEK----------LGCSASNFVFARTMP---AEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVE---DQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHRK-RNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENN------------PVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPG-FREVSFYYSEE------------NKLPEPE----ELDLEPE-------------------NMESVPLDPS-------------------ASSSS------------------------------------------------------------------------------------------------LPLPDRHSGHKAENGPGP------GVLVLRASFDERQPYAHMNGG-----RKNERALPLPQSSTC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PBN6-1", "uniprot_id": "A0A8M1PBN6_DANRE", "id": "A0A8M1PBN6-1", "name": "Tyrosine-protein kinase receptor", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRSSKQRRYWTLFSGLVLVLSTL----CHGEICG----------------------------------------------------------------------------------------------------------------PGIDIGNDIGNFKRLENCTVIEGYLQILLIGDKNSNNQEVFRTLSFPKLTMITDYLLLFRVSGLESLSTLFPNLAVIRGRNLFYNCALVIFELTSLKDIGLYNLRNITRGAIRIEKNPELCYLDSVDWSLILDAELNNFIDGNKQSKE---CGNVCPGIMEDNSQCT-------------------RCWTSNHCQKVCR--CGQRACTDSGQCCHPQCLGSCSVPDS-DRACAACQNYNHEGRCVEDCPPGTYKFEGWRCITRDFCS---KVHLPDYDRFVIHAGECISDCPPGFTRDESHGVSVSMLCTACDG-PCDKICD-----EKVIDSVDAAQSLKGCTVIKG--NLHINIRR--GTNIASELENFLGLIKTVTGYIKIRSSHTLTSLSFLKSLRYIHGEELWDN-TYAFAALDNQHLQLLWDWSQHNLTISEGKLYFRLNPKLCMSEIRKMWAKTGIKDNFV-ERDF--RNNGDRASCGTKILKFTSNNTRSNQIKLMWESYRPSD--SRDLVNFIVYYKEAPFQNITEFDGQDSCGSDSWDMVNVDLPDEKILNPG----VVLSTLKPWTQYAIFVKAVTLIVEDRDRDKDRLHLGPQSEVVYIRTKPSAPSMPVDIRAYANSSSKLVVRWAPPLAPNGNNTYYVLRWKQQGEDRELYQHNYCSKELKIPVRVSATGLTDTEDTKP-TYHETGGRDKTPCCPCPKTEEDLKRIEDDIYYRKAFENFLHNAIFTPRPP-------------------------------DRRRR---------DLFGVANVTSIHTLLAGHWNLTEGN----FSDDEPPRREFSFLERKVKER-----HIEITGLQPFTVYRIDLHACNEEVR------------HCSAAAFVFSRTKA---AEKADDIPGSVTWEGQ-EDSVFLKWPEPDKPNGLIMLYEIQYRLGTEP--EKHECVSRQHYRKHKGVKLSNLGPGNYSVRVRATSLAGNGSWTEPIAFSVHQLEQSSYDPVMFIAILPALLLIAG-LVVFGYTWMNKNRNNDRLGNGVLYASVNPEYFSAAEMYVPDEWEVEREKITMCRELGQGSFGMVYEGIAKGVVKDEPETRVAIKTVNESASLHERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLR-SVENTS-----------SLPLPP-LKKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTNSDVWSFGVVLWEIATLAEQPYQGMSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEDLEAG-FKETSFFYSEE------------NKPPDTE----ELDMENVG------------------TMENVPLEPSSSLQPLAPSISPPQQCTAAAQSCS------------------------------------------------------------------------------------------------TPSSPPSSPSSTDKHPLPTSAANGPSMVLRGPFEEGQPYAHMNGG-----RKNDRALPLPQSSAC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09208-1", "uniprot_id": "INSR_DROME", "id": "P09208-1", "name": "Insulin-like receptor", "aln": "MFNMPRGVTKSKSKRGKIKMENDMAAAATTTACTLGHICVLCRQEMLLDTCCCRQAVEAVDSPASSEEAYSSSNSSSCQASSEISAEEVWFLSHDDIVLCRRPKFDEVETTGKKRDVKCSGHQCSNECDDGSTKNNRQQRENFNIFSNCHNILRTLQSLLLLMFNCGIFNKRRRRQHQQQHHHHYQHHHQQHHQQHHQRQQANVSYTKFLLLLQTLAAATTRLSLSPKNYKQQQQLQHNQQLPRATPQQKQQEKDRHKCFHYKHNYSYSPGISLLLFILLANTLAIQAVVLPAHQQHLLHNDIADGLDKTALSVSGTQSRWTRSESNPTMRLSQNVKPCKSMDIRNMVSHFNQLENCTVIEGFLLIDLIN------DASPLNRSFPKLTEVTDYIIIYRVTGLHSLSKIFPNLSVIRGNKLFDGYALVVYSNFDLMDLGLHKLRSITRGGVRIEKNHKLCYDRTIDWLEILAENETQLVVLTENGKEKECRLSKCPGEIRIEEGHDTTAIEGELNASCQLHNNRRLCWNSKLCQTKCPEKCRNN-CIDEHTCCSQDCLGGCVIDKNGNESCISCRNVSFNNICMDSCPKGYYQFD-SRCVTANECITLTKFETNSVYSGIPYNGQCITHCPTGYQKSENK-----RMCEPCPGGKCDKECS-----SGLIDSLERAREFHGCTIITGTEPLTISIKRESGAHVMDELKYGLAAVHKIQSSLMVHLTYGLKSLKFFQSLTEISGDPPMDADKYALYVLDNRDLDELWGPNQ-TVFIRKGGVFFHFNPKLCVSTINQLLPMLASKPKFFEKSDVGADSNGNRGSCGTAVLNVTLQSVGANSAMLNVTTKVEIGEPQKPSNATIVFKDPRAFIGFVFYHMIDPYGNSTKSSDDPCDDRWKVSSPEKSGVMVLSNLIPYTNYSYYVRTMAISSELT---------NAESDVKNFRTNPGRPSKVTEVVATAISDSKINVTWSYLDKPYGVLTRYFIKAKLINRPTRNNNRDYCTEP---LVKAMEN---DLPATTPTKKISDPLAGDCKCVEGSKKTSSQEYDDRKVQAGMEFENALQNFIFVPNIRKSKNGSSDKSDGAEGAALDSNAIPNGGATNPSRRRRDVALEPELDDVEGSVLLRHVRSITDDTDAFFEKDDENTYKDEEDLSSNKQFYEVFAKELPPNQTHFVFEKLRHFTRYAIFVVACREEIPSEKLRDTSFKKSLCSDYDTVFQTTKRKKFADIVMDLKVDLEHANNTESPVRVRWTPPVDPNGEIVTYEVAYKLQKPDQVEEKKCIPAADFNQTAG-YLIKLNEGLYSFRVRANSIAGYGDFTEVEHIKVEPPPSYAKVFFWLLGIG-LAFLIVSLFGYVCYLHKRKVPSND------LHMNTEVNPFYASMQYIPDDWEVLRENIIQLAPLGQGSFGMVYEGILKSFPPNGVDRECAIKTVNENATDRERTNFLSEASVMKEFDTYHVVRLLGVCSRGQPALVVMELMKKGDLKSYLRAHRPEERDEAMMTYLNRIGVTGNVQPPTYGRIYQMAIEIADGMAYLAAKKFVHRDLAARNCMVADDLTVKIGDFGMTRDIYETDYYRKGTKGLLPVRWMPPESLRDGVYSSASDVFSFGVVLWEMATLAAQPYQGLSNEQVLRYVIDGGVMERPENCPDFLHKLMQRCWHHRSSARPSFLDIIAYLEPQCPNSQFKEVSFYHSEAGLQHREKERKERNQLDAFAAVPLDQDLQDREQQEDATTPLRMGDYQQNSSLDQPPESPIAMVDDQGSHLPFSLPSGFIASSTPDGQTVMATAFQNIPAAQGDISATYVVPDADALDGDRGYEIYDPSPKCAELPTSRSGSTGGGKLSGEQHLLPRKGRQPTIMSSSMPDDVIGGSSLQPSTASAGSSNASSHTGRPSLKKTVADSVRNKANFINRHLFNHKRTGSNASHKSNASNAPSTSSNTNLTSHPVAMGNLGTIESGGSGSAGSYTGTPRFYTPSATPGGGSGMAISDNPNYRLLDESIASEQATILTTSSPNPNYEMMHPPTSLVSTNPNYMPMNETPVQMAGVTISHNPNYQPMQAPLNARQSQSSSDEDNEQEEDDEDEDDDVDDEHVEHIKMERMPLSRPRQRALPSKTQPPRSRSVSQTRKSPTNPNSGIGATGAGNRSNLLKENWLRPASTPRPPPPNGFIGREA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . :::: :* .:. .:** * ::::*********:* * **. . ***** :*:*::::**:**.**. :****:**** :** . ***::. .* *:**::**.****.:***** .*** ::** ** .: : .: ** . *** :. : **.:: **. * * :. * :. ** :***.* .. : :* :*:: . . *: ** . *:*: **: : * . . . : : .:*: .**.*: :. .: * .* * * * * ***: *: ::***::.* * *.*:* * :: .**: :. :. : . : :: :: * **.*::.* * *: : .*:: .***:.*: **. .: .: : * ::* :*****:* * :: . * . : *. .**:*.** : :*..* .. * : . : *: . .* ... :. *. *..: . : * .* ::* * *:*:*: :*::::: ..:*:: :**:.. ** :: : : *.*:: * * * * : *.:: : . .::**:: :: * .. . . * .*. . : . . *** *:* **.*. .*:** *: . : : . : .* * : * * ..: : : *: ** * * : :*..* ** ** * *: . *: : . *..: ::*. * .*** *: **: * ::::*:. .:.: * * .*. * *: *::*.*::* *.:*: : * ::.: :**.. : . * .* .*. *: ..: : * *: *:**:*** **:* ************: *.. : : . ******* *: :** :**.********: :******** *:***:**:****.:********: * . .: ** :: *** ********* *:***************:*:********************** *********.****:***::: ***:********:**** *****:*******:*::**::::*:****:*.:**: **::... *****:**. :: : . *:*.**::** *: : ::: .::. * .* *.* . . . * .:.. : :. * : : : * . * : * * ..*.: ", "identical_positions": 444, "similar_positions": 397, "identity": "20.31%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020503-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15127-1", "uniprot_id": "INSR_RAT", "id": "P15127-1", "name": "Insulin receptor", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSGRGC--------------------------------ETTAVPLLMAVAVAG-GTAGHLYPG-------EVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDYVEDNYIVLNKD--DNEECGDVCPGTAKGKTNCPATVINGQFVER---------CWTHSHCQKVCPTICKSHGCTAEGLCCHKECLGNCSEPDDPTK-CVACRNFYLDGQCVETCPPPYYHFQDWRCVNFSFCQDLHYKCRNSRKPGCHQYVIHNNKCIPECPSGYT-MNSSNLMCTPCLG-PCPKVCQILEGEKTIDSVTSAQELRGCTVING--SLIINIR--GGNNLAAELEANLGLIEEISGFLKIRRSYALVSLSFFRKLHLIRGET-LEIGNYSFYALDNQNLRQLWDWNKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTK-GRQERNDIALKTNGDQASCENELLKFSFIRTSFDKILLRWEPYWPP--DFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPQRSNDPKSQTPSHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVYWERQAEDSELFELDYCLKGLKLPSRTWSPPFESDDSQKHNQSEYDDSASECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRKTSSGNGAED--------------------TRPSRKRR---SLEEVGNVTAT--TPTLPDFPNISSTIAPTSHEEHRPFEKVVN----------------KESLVISGLRHFTGYRIELQACNQDSPEERSGVAAYVS---------ARTMPEAKADDIVGPVTHEIFENN----VVHLMWQEPKEPNGLIVLYEVSYRR-YGD-EELHLCVSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNAKDIIKGEVETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSHLRSLRPDAEN------------NPGRPPPTLQEMIQMTAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPS-FPEVSFFYSEE---NKAPESEE-----------LEMEFEDMEN----VPLDRSSHCQREEAGCREGGSSLSIKRTYDEHIPYTHMN-------------------------------------------------------------------GGKKNGRVLTLPR-------------------------------SNPS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15208-1", "uniprot_id": "INSR_MOUSE", "id": "P15208-1", "name": "Insulin receptor", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGFGRGC--------------------------------ETTAVPLLVAVAALLVGTAGHLYPG-------EVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKD--DNEECGDVCPGTAKGKTNCPATVINGQFVER---------CWTHSHCQKVCPTICKSHGCTAEGLCCHKECLGNCSEPDDPTK-CVACRNFYLDGQCVETCPPPYYHFQDWRCVNFSFCQDLHFKCRNSRKPGCHQYVIHNNKCIPECPSGYT-MNSSNLMCTPCLG-PCPKVCQILEGEKTIDSVTSAQELRGCTVING--SLIINIR--GGNNLAAELEANLGLIEEISGFLKIRRSYALVSLSFFRKLHLIRGET-LEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTK-GRQERNDIALKTNGDQASCENELLKFSFIRTSFDKILLRWEPYWPP--DFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPQRSNDPKSQTPSHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVYWERQAEDSELFELDYCLKGLKLPSRTWSPPFESDDSQKHNQSEYDDSASECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFVP--------------------------------RPSRKRR---SLEEVGNVTAT--TLTLPDFPNVSSTIVPTSQEEHRPFEKVVN----------------KESLVISGLRHFTGYRIELQACNQDSPDERCSVAAYVS---------ARTMPEAKADDIVGPVTHEIFENN----VVHLMWQEPKEPNGLIVLYEVSYRR-YGD-EELHLCVSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNAKDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSHLRSLRPDAEN------------NPGRPPPTLQEMIQMTAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPS-FPEVSFFYSEE---NKAPESEE-----------LEMEFEDMEN----VPLDRSSHCQREEAGGREGGSSLSIKRTYDEHIPYTHMN-------------------------------------------------------------------GGKKNGRVLTLPR-------------------------------SNPS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06213-1", "uniprot_id": "INSR_HUMAN", "id": "P06213-1", "name": "Insulin receptor", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATGGRR--------------------------------GAAAAPLLVAVAALLLGAAGHLYPG-------EVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKD--DNEECGDICPGTAKGKTNCPATVINGQFVER---------CWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTK-CVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYT-MNSSNLLCTPCLG-PCPKVCHLLEGEKTIDSVTSAQELRGCTVING--SLIINIR--GGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGET-LEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTK-GRQERNDIALKTNGDQASCENELLKFSYIRTSFDKILLRWEPYWPP--DFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQN--HPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWERQAEDSELFELDYCLKGLKLPSRTWSPPFESEDSQKHNQSEYEDSAGECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRKTSSGTGAED--------------------PRPSRKRR---SLGDVGNVTVA--VPTVAAFPNTSSTSVPTSPEEHRPFEKVVN----------------KESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYVS---------ARTMPEAKADDIVGPVTHEIFENN----VVHLMWQEPKEPNGLIVLYEVSYRR-YGD-EELHLCVSRKHFALERGCRLRGLSPGNYSVRIRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAEN------------NPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPS-FPEVSFFHSEE---NKAPESEE-----------LEMEFEDMEN----VPLDRSSHCQREEAGGRDGGSSLGFKRSYEEHIPYTHMN-------------------------------------------------------------------GGKKNGRILTLPR-------------------------------SNPS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GDS8-1", "uniprot_id": "A0AC58GDS8_DANRE", "id": "A0AC58GDS8-1", "name": "Tyrosine-protein kinase receptor", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMTHYHLKMVSGDGVNRRRMTTLD----------------------TDKIARHTTTHTRKRHQDTVGTLGAEKETTGTTYICSSKDIRNNVTNLRVLENCTVIEGHLKILLMFTTKPEDFRGLSYPKLTVVTDYLLLFRVYGLESLSDLFPNLTVVRGNNLFFNYALVLFEMLQLKEIGLHSLMNITRGAVRVEKNPDLCYLSTLDWSMILDSVEDNYIVANKN--DRE-CGDICPGTVLGKTTCPLTTINGDFSER---------CWNQKYCQRMCPSSCKHRACTKDNQCCHDQCLGGCLEPHSSNK-CVACRNFMHNNMCVEKCPHGFYTFKGWRCVSFSFCQELHNKCKQG-KGDCHEYVIHNGACIPECPSGYTTVNSTTLNCTPCAG-LCPKVCMGL---KTVDSVTAAQALRGCTVING--SLVINIR--GGNNIAAELEANLGQLEEITGYLTVRHSYALVSLSFLRKLRIIHGET-QEVGNYSFYALDNQNLRQLWDWSKHNLTIQQGRMFFHHNSKLCMSEIRRMEEVTGTK-NRQTKNDIVSKTNGDQASCESKVLKFTRISTLSDKIIIKWEAFWPP--DFRDLLGFMVLYKEAPYKNVTEFDGQDACGSNSWVIADVDPPPRATEGKEHE---PGYLIFPLKPWTQYAIMVKTQLSASDEHQVHGAKSEIIYVRTNATKPSVPLDPISSSNSSSQIILKWKPPNDPNGNITHYLVFCQQQPEASELYKFDYCQKGMKLPTRAPT-QVDNEEEQKWNQTEEQGPDSRCCACPKTEKQLKKEAEETEYRKTFENYLHNEVFEL--------------------------------RPSRQRR---SLVGIANRTSSRLFTTPSSLPNGSATRSPEEEAEANKISLIVQA---------------KESTVISNLRHFTSYQIEIHACNHGSDPTRCSMAAYVS---------ARTMPEEKADDIVGKITCEVSEY-----SVHIRWIEPKAPNGMIILYEVHYKR-LGDTEELHHCVSRKNYIADGGCKLRVVHPGNYTVRIRATSLAGNGSWTEPTHFYVQDLRVDPSNVLKIVIGPVICFFLLLLLCVGFYIVKKK-QTEGPTGRLYTSPNPEYFS-----PDEVYEPDEWEVPREKITLLRELGQGSFGMVYEGNGKDIVKGESQTRVAVKTVNESASLRERIEFLNEASVMKAFSCHHVVRLLGVVSKGQPTLVVMELMTHGDLKSFLRSLRPDSEN------------NPGRPPPTLKEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAEDLTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTAHSDCWSFGVVLWEVSTLAEQPYQGLSNEQVLKFVMEGGYLDRPDNCADRLHNLMQMCWHYNPKMRPTFQEIIEMLREDLHPS-FQEVSFFYSEE---NKPPETEE-----------FDMDLENMES----IPLDPSSYSQRECCLDGDEGSSVGLRGSYEEHVPYTHMN-------------------------------------------------------------------GGKKNGRILSLPR-------------------------------STPS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09208-1", "uniprot_id": "INSR_DROME", "id": "P09208-1", "name": "Insulin-like receptor", "aln": "MFNMPRGVTKSKSKRGKIKMENDMAAAATTTACTLGHICVLCRQEMLLDTCCCRQAVEAVDSPASSEEAYSSSNSSSCQASSEISAEEVWFLSHDDIVLCRRPKFDEVETTGKKRDVKCSGHQCSNECDDGSTKNNRQQRENFNIFSNCHNILRTLQSLLLLMFNCGIFNKRRRRQHQQQHHHHYQHHHQQHHQQHHQRQQANVSYTKFLLLLQTLAAATTRLSLSPKNYKQQQQLQHNQQLPRATPQQKQQEKDRHKCFHYKHNYSYSPGISLLLFILLANTLAIQAVVLPAHQQHLLHNDIADGLDKTALSVSGTQSRWTRSESNPTMRLSQNVKPCKSMDIRNMVSHFNQLENCTVIEGFLLIDLINDASP---LNRSFPKLTEVTDYIIIYRVTGLHSLSKIFPNLSVIRGNKLFDGYALVVYSNFDLMDLGLHKLRSITRGGVRIEKNHKLCYDRTIDWLEILAENETQLVVLTENGKEKECRLSKCPGEIRIEEGHDTTAIEGELNASCQLHNNRRLCWNSKLCQTKCPEKCRNN-CIDEHTCCSQDCLGGCVIDKNGNESCISCRNVSFNNICMDSCPKGYYQFDS-RCVTANECITLTKFETNS----VYSGIPYNGQCITHCPTGYQ-KSENKRMCEPCPGGKCDKECSSG----LIDSLERAREFHGCTIITGTEPLTISIKRESGAHVMDELKYGLAAVHKIQSSLMVHLTYGLKSLKFFQSLTEISGDPPMDADKYALYVLDNRDLDELWGP-NQTVFIRKGGVFFHFNPKLCVSTINQLLPMLASKPKFFEKSDVGADSNGNRGSCGTAVLNVTLQSVGANSAMLNVTTKVEIGEPQKPSNATIVFKDPRAFIGFVFYHMIDPYGNSTKSSDDPCDDRWKVSSPEKS---GVMVLSNLIPYTNYSYYVRTMAISS---ELTNAESDVKNFRTNPGRPSKVTEVVATAISDSKINVTWSYLDKPYGVLTRYFIKAKLINRPTRNNNRDYCTEPLVKAMENDLPATTP----TKKISDPLAGDCKCVEGSKKTSSQEYDDRKVQAGMEFENALQNFIFVPNIRKSKNGSSDKSDGAEGAALDSNAIPNGGATNPSRRRRDVALEPELDDVEGSVLLRHVRSITDDTDAFFEKDDENTYKDEEDLSSNKQFYEVFAKELPPNQTHFVFEKLRHFTRYAIFVVACREEIPSEKLRDTSFKKSLCSDYDTVFQTTKRKKFADIVMDLKVDLEHANNTESPVRVRWTPPVDPNGEIVTYEVAYKLQKPDQVEEKKCIPAADFNQTAGYLIK-LNEGLYSFRVRANSIAGYGDFTEVEHIKVEPPPS-YAKVFFWLLGIGLAFLIVSLFGYVCYLHKRKVPSND--LHMNTEVNPFYAS-------MQYIPDDWEVLRENIIQLAPLGQGSFGMVYEGILKSFPPNGVDRECAIKTVNENATDRERTNFLSEASVMKEFDTYHVVRLLGVCSRGQPALVVMELMKKGDLKSYLRAHRPEERDEAMMTYLNRIGVTGNVQPPTYGRIYQMAIEIADGMAYLAAKKFVHRDLAARNCMVADDLTVKIGDFGMTRDIYETDYYRKGTKGLLPVRWMPPESLRDGVYSSASDVFSFGVVLWEMATLAAQPYQGLSNEQVLRYVIDGGVMERPENCPDFLHKLMQRCWHHRSSARPSFLDIIAYLEPQCPNSQFKEVSFYHSEAGLQHREKERKERNQLDAFAAVPLDQDLQDREQQEDATTPLRMGDYQQNSSLDQPPESPIAMVDDQGSHLPFSLPSGFIASSTPDGQTVMATAFQNIPAAQGDISATYVVPDADALDGDRGYEIYDPSPKCAELPTSRSGSTGGGKLSGEQHLLPRKGRQPTIMSSSMPDDVIGGSSLQPSTASAGSSNASSHTGRPSLKKTVADSVRNKANFINRHLFNHKRTGSNASHKSNASNAPSTSSNTNLTSHPVAMGNLGTIESGGSGSAGSYTGTPRFYTPSATPGGGSGMAISDNPNYRLLDESIASEQATILTTSSPNPNYEMMHPPTSLVSTNPNYMPMNETPVQMAGVTISHNPNYQPMQAPLNARQSQSSSDEDNEQEEDDEDEDDDVDDEHVEHIKMERMPLSRPRQRALPSKTQPPRSRSVSQTRKSPTNPNSGIGATGAGNRSNLLKENWLRPASTPRPPPPNGFIGREA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . * . **** ::.:. ****:****.* * *: : * . *:*** :***::::** **.**..:****:*:**..** .****::. ..* ::**:.* .****.**:*** .*** *:** ** * : :* .:: :.* . *** : *.*:*:: **. . ** ** *: . * : ** .:***.* .. .: *::***. :. *::.** :* *.. ***. . * * :. :. : :*. **..**:** .... * ** * * * * :**: *: ::***:*.* .* *.*: .* :: **: .*. :.:* . * :: :*.* **.*::.* * *:. : .:*::*.***::* :**. ::.: * :* :***.*.***:* *.:: : .:* :.*: .:**::.** . :*:.: . :. ::. . : . ::: . .: ... :. *. *..: * . .: :: * *:*:*: *:* * . .*:*:: .:*:. .** : :: : *.*:* :.*. ..* * :*:*:: : . :. : *** : : . . . : :: .* .*. .. : .: . **: *:* :* .***:** : : : :.: : : . : . :. : *:. ***** * * : **.. : ::: . :* . * *** :. :: . *:: * * *** *: *** *: * * : *:. .: * :: : * *:.*:**.*:** *.:** :: * ::: ::* : .::. :. *: :* .:. : :. ** * * * **:*** **:* * ************ :.: . : . *:*****.*: *** :**.****** * :******** *:***:******* :*****.**: **: .: . . *** .: **: ********* *****************.*:********************** *********.****:***::: ** :********:::** ************::*::** :: *:**.: : .**: **:.... **:* :*: *. : * * ****::** :: * :* :: :::: *. . . *:: . *.:.: .*:*:: . *** .*. *** *..* ", "identical_positions": 455, "similar_positions": 411, "identity": "20.87%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020506-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63132-1", "uniprot_id": "ROS1_RAT", "id": "Q63132-1", "name": "Proto-oncogene tyrosine-protein kinase ROS", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKRIRWLTPKPATFVVLGC-VWISVAQGTILSSCLTSCVTNLGRQLDSGTRYNLSEACIQGCQFWNSIDQEKCALKCNDTYVTICERESCEVGCSNAEGSYEEEVLDNTELPTAPFASSIG--------SNGVTLRWNPAN----ISGVKYIIQWKYAQLPGSWAYTETVSK-----------------------LSYMVEPLHPFTEYIFRVVWIFTAQLH--LYSPPSPSYRTHPYGVPETAPFITNIESSSPDTVEVSWAPPYFPGGPILGYNLRLISKTQKLDSGTQRTSFQ----FYSTLPNTTYRFSIAAVNEVGEGPEAESMITTPSPAVQEEEQWLFLSRKTSLRKRS-LKYLVDEAHCLWSDAIRHNITGISVNTQQEVVYFS----EGTIIWMKGAANMSDVSDLRIFYR----GSALVSSISVDWLYQRMYFIMDNRVHVCDLKHCSN-------LEEITPFSIVAPQKVVVDSYNGYVFYLLRDGIYRVHLPLPSVRDTKAVRIVESGTLKDFAVKPQSKRIIYFNGTMQVFMSTFLDGSAFHRVLPWVPLADVK---------SFACENNDFLITDGKAIFQQDSLS----FNEFIVGCDLSHIEEFGFGNLVIFGSSVQSYPLPGHPQEVSVLFGSREALIQWKPPI----LAIGA--------------SPSAWQNWTYEVKVSSQDILETTQVFLNISRTVLNVPKLQSSTKYMVSVRASSPKGPGPWSEPSVGTTLVPATEPPFIMAVKEDGLWSKPLSSFGPGEFLSSDVGNVSDMDWYNNSLYYSDTKGNVYVRPLNGMDISENYHISSIAGACALAFEWLGHFLYWAGKT-YVIQRQSVLTGHTDIVTHVKLLVNDMAVDPVGGYLYWTTLYSVESTRLNGESSLVLQAQPWLSGKKVIALTLDLSDGLLYWLVQDNQCIHLYTAVLRGWSGADATITEFAAWSTSEISQNALMYYSGRLFWINGF-RIITAQEIGQRTSVSVSEPGKFNQFTIIQTSLKPLPGNFSSTPTVIPDSVQESSFRIEGHTSSFRILWNEPPAVDWGIVFYSVEFSAHSKFLAIEQQSLPVFTVEGLEPYALFNLSVTPYTYWGKGQKTSLSFRAPESVPSAPENPRIFILSLGRYTRKNEVVVEFRWNKPKHENGVLTKSEIFYHISKQSGTNKSTEDWVSVSVTPPVMSFQLEAMSPGYIVSFQVRVFTSKGPGPFSDIVMSKTSEIKPCPYLISLLGNKIEFLDMDQNQVVWTFSLEGAVSTVGYTADDEMGYFAQGDALFLLNLHNHSSSKLFQDVLASDIAVIAVDWIARHLYFALKASQDGTQIFDVDLEHKVKSPREVKICKSHTAIISFSMYPLLSRLYWTEVSDLGYQMFYCNISSHTLHHVLQPKASNQHG-RRQCSCNVTESELSGAMTVDTSDPDRPWIYFTKQQEIWAMDLEGCQCWKVIMVPATPG-KRIISLTVDGEFIYWITTMKDDTEIYQAKKGSGAILSQVKAPRSKHILAYSSALQPFPDKAYLSVASNMVEASILNATNTSLILKLPPVKTNLTWHGITTPTSTYLVYYMEAN-RANSSDRKHNMLESQENVARIEGLQPFSTYVIQIAVKNYYSDPLEHLSLGKEIQGKTKSGVPGAVCHINATVLSDTSLLVFWTESHKPNGPKELVRYQLVMSYLAPIPETPLRQDEFPSARLSLLVTKLSGGQQYVLKILACHSEEMWCTESHPVSVNMFDTPEKPSALVPENTSLLLDWKAPSNANLTRFWFELQKWKYSEFYHVKASCSQGPVYVCNIANLQPYTPYNIRVVVVYTTGENSSSIPESFKTKAGVPSKPGIPKLLEGSKNSI--QWEKAEDNGNRLMYYTLEVRKSISNDSRDQSLRWT----------------------AVFNGSCSSICTWRSKNLKGTFQFRAVASNAIGFGEYSEISEDITLVEDGFWITETSFILTIIVGIFLVATVPLTFVWHRSLK--NHKATKEGLSVLNDNDQELAELRGLAAGVGLANACYAVHTLPTQEEIESLPAFPREKLSLRLLLGSGAFGEVYEGTAVDILGRGSG-EIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLSEPQYIILELMEGGDLLSYLRKARGTTLSGP----LLTLADLVELCVDISKGCVYLEQMHFIHRDLAARNCLVSVKDYTSP--RVVKIGDFGLAREIYKHDYYRKRGEGLLPVRWMAPENLMDGIFTSQSDVWSFGILVWEILTLGHQPYPAHSNLDVLNYVQAGGRLEPPRNCPDDLWNLMFRCWAQEPDQRPTFYNIQDQLQLFRNVSLNNVSHCGQAAPAGGVINKGFEGEDNEMAT-LNSDDTMPVALMETRNQEGLNYMVLATKCSQSEDRYEGPLGSKESGLHDLKKDERQP-ADKDFCQQPQVAYGSPGHSEGLNYACLAHSGHGDVSE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q78DX7-1", "uniprot_id": "ROS1_MOUSE", "id": "Q78DX7-1", "name": "Proto-oncogene tyrosine-protein kinase ROS", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKNICWLTLKLVKFVVLGCIIWISVAQSTVLSSCLTSCVTNLGRQLDSGTRYNLSEACIHGCQFWNSVDQETCALKCNDTYATICERESCEVGCSNAEGSYEEEVLESTELPTAPFASSIG--------SHGVTLRWNPAN----ISGVKYIIQWKYAQLPGSWTFTETVSK-----------------------LSYTVEPLHPFTEYIFRVVWIFTAQLH--LYSPPSPSYRTHPYGVPETAPLILNMESWSPDTVEVSWAPPHFPGGPILGYNLRLISKNQKLDSGTQRTSFQ----FYSTLPNTTYRFSIAAVNEVGEGPEAESTVTTPSPSVQEEEQWLFLSRKTSLRKRS-LKYLVDEAHCLWSDAIHHNITGISVYAQQQVVYFS----EGTVIWMKGAANMSDVSDLRIFYQ----GSGLVSSISIDWLYQRMYFIMDKLVYVCELKNCSN-------LEEITPFSLIAPQKVVVDSYNGYLFYLLRDGIYRVNLPLPSGRDTKAVRIVESGTLKDFAVKPQSKRIIYFNDTMQLFMSTFLDGSAFHRVLPWVPLVTVK---------SFACENNDFLITDGKAIFQQDSLS----FNEFIVGCDLSHIEEFGFGNLVIFGSSVQSYPLPGHPQEVSVLFGSREALIQWTPPA----LAIGA--------------SPSAWQNWTYEVKVYSQDILEITQVFSNISGTMLNVPELQSSTKYTVSVRASSPKGPGPWSAPSVGTTLVPATEPPFIMAVKEDGLWSKPLCSFGPGEFLSSDVGNVSDMDWYNNSLYYSDTKGNVYVRPLNGMDISENYHIPSIVGAGALAFEWLGHFLYWAGKT-YVIQRQSVLTGHTDIVTHVKLLVNDMAVDSVGGYLYWTTLYSVESTRLNGESSLVLQAQPWLSGKKVIALTLDLSDGLLYWLVQDNQCIHLYTAVLRGWSGGDATITEFAAWSTSEISQNALMYYSGRLFWINGF-RIITAQEIGQRTSVSVSEPAKFNQFTIIQTSLKPLPGNFSSTPKVIPDPVQESSFRIEGHTSSFQILWNEPPAVDWGIVFYSVEFSTHSKFLIIEQQSLPIFTVEGLEPYTLFNLSVTPYTYWGKGQKTSLSFRAPESVPSAPENPRIFILSSGRYTKKNEVVVEFRWNKPKHENGVLTKFEIFYHISKQSGTNRSTEDWMSASVIPPVMSFQLEAVSPEYTVAFQVRVFTSKGPGPFSDIVMSKTSEIKPCPYLISLLGNKIVFLDMDQNQVLWTFSLEGDVSTVGYTTDDEMGYFAQGDTLFLLNLRNHSSSKLFQDALVSDIRVIAVDWIARHLYFALKASQNGTQIFNVDLEHKVKSPREVKTCKAHTTIISFSIYPLLSRLYWTEVSDLGHQMFYCNISNHTSQHVLQPKASNQHG-RSQCSCNVTESELSGAMTVDTSDPDRPWIYFTKRQEIWAMDLEGCQCWKVIMVPTIPG-KRIISLTVDGEFIYWIMKTKDDAQIYQAKKGSGAILSQVKASRSKHILAYSSALQPFPDKAYLSLASDMVEATILYATNTSLTLKLPPVKTNLTWHGITHPTSTYLIYYMEAN-RANSSDRRHKMLESQENVARIEGLQPFSMYMIQIAVKNYYSEPLEHLPLGKEIQGQTKSGVPGAVCHINATVLSDTSLHVFWTESHKPNGPKESVRYQLVMSYLAPIPETPLRQGEFPSAKLSLLITKLSGGQLYVMKVLACHPEEMWCTESHPVSVNMFDTPEKPSALVPENTSLQLDWKARSNVNLTGFWFELQKWKYNEFYHVKASCSQGPVYVCNITDLQPYTSYNIRVVVVYTTGENSSSIPESFKTKAGVPSKPGIPKLLEGSKNSI--QWEKAEDNGSRLMYYTLEVRKGISNDSQNQSSRWK----------------------VVFNGSCSSICTWRSKNLKGTFQFRAVAANEIGLGEYSEISEDITLVEDGVWITETSFILTIIVGIFLVATVPLTFVWHRSLK--SHKASKEGLSVLNDNDKELAELRGLAAGVGLANACYAVHTVPTQEEIENLPAFPREKLSLRLLLGSGAFGEVYEGTAIDILGVGSG-EIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLGEPQYIILELMEGGDLLSYLRKARGTTFHGP----SLTLLDLVELCVDISKGCVYLEQMHFIHRDLAARNCLVSVKDYTSP--RVVKIGDFGLAREIYKNDYYRKRGEGLLPVRWMAPENLMDGIFTSQSDVWSFGILVWEILTLGHQPYPAHSNLDVLNYVQAGGRLEPPRNCPDDLWNLMSQCWAQEPDQRPTFHNIQNQLQLFRNVFLNNVSHCGEAAPTGGVINKGFEGEDDEMVT-LNSDDTMPVALMETKNQEGLNYMVLATKCSQGEGSYEGPLGPKELGSCDLKKDKKQPQADKDFCQEPQVAYGSPGLSEGLNYACLAHSEHGDVSE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08922-1", "uniprot_id": "ROS1_HUMAN", "id": "P08922-1", "name": "Proto-oncogene tyrosine-protein kinase ROS", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKNIYCLIPKLVNFATLGC-LWISVVQCTVLNSCLKSCVTNLGQQLDLGTPHNLSEPCIQGCHFWNSVDQKNCALKC---------RESCEVGCSSAEGAYEEEVLENADLPTAPFASSIG--------SHNMTLRWKSAN----FSGVKYIIQWKYAQLLGSWTYTKTVSR-----------------------PSYVVKPLHPFTEYIFRVVWIFTAQLQ--LYSPPSPSYRTHPHGVPETAPLIRNIESSSPDTVEVSWDPPQFPGGPILGYNLRLISKNQKLDAGTQRTSFQ----FYSTLPNTIYRFSIAAVNEVGEGPEAESSITTSSSAVQQEEQWLFLSRKTSLRKRS-LKHLVDEAHCLRLDAIYHNITGISVDVHQQIVYFS----EGTLIWAKKAANMSDVSDLRIFYR----GSGLISSISIDWLYQRMYFIMDELVCVCDLENCSN-------IEEITPPSISAPQKIVADSYNGYVFYLLRDGIYRADLPVPSGRCAEAVRIVESCTLKDFAIKPQAKRIIYFNDTAQVFMSTFLDGSASHLILPRIPFADVK---------SFACENNDFLVTDGKVIFQQDALS----FNEFIVGCDLSHIEEFGFGNLVIFGSSSQLHPLPGRPQELSVLFGSHQALVQWKPPA----LAIGANVILISDIIELFELGPSAWQNWTYEVKVSTQDPPEVTHIFLNISGTMLNVPELQSAMKYKVSVRASSPKRPGPWSEPSVGTTLVPASEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDTKGDVFVWLLNGTDISENYHLPSIAGAGALAFEWLGHFLYWAGKT-YVIQRQSVLTGHTDIVTHVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLVLQTQPWFSGKKVIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQSTGDTTITEFAAWSTSEISQNALMYYSGRLFWINGF-RIITTQEIGQKTSVSVLEPARFNQFTIIQTSLKPLPGNFSFTPKVIPDSVQESSFRIEGNASSFQILWNGPPAVDWGVVFYSVEFSAHSKFLASEQHSLPVFTVEGLEPYALFNLSVTPYTYWGKGPKTSLSLRAPETVPSAPENPRIFILPSGKCCNKNEVVVEFRWNKPKHENGVLTKFEIFYNISNQSITNKTCEDWIAVNVTPSVMSFQLEGMSPRCFIAFQVRAFTSKGPGPYADVVKSTTSEINPFPHLITLLGNKIVFLDMDQNQVVWTFSAERVISAVCYTADNEMGYYAEGDSLFLLHLHNRSSSELFQDSLVFDITVITIDWISRHLYFALKESQNGMQVFDVDLEHKVKYPREVKIHNRNSTIISFSVYPLLSRLYWTEVSNFGYQMFYYSIISHTLHRILQPTATNQQNKRNQCSCNVTEFELSGAMAIDTSNLEKPLIYFAKAQEIWAMDLEGCQCWRVITVPAMLAGKTLVSLTVDGDLIYWIITAKDSTQIYQAKKGNGAIVSQVKALRSRHILAYSSVMQPFPDKAFLSLASDTVEPTILNATNTSLTIRLPLAKTNLTWYGITSPTPTYLVYYAEVNDRKNSSDLKYRILEFQDSIALIEDLQPFSTYMIQIAVKNYYSDPLEHLPPGKEIWGKTKNGVPEAVQLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAISHLALIPETPLRQSEFPNGRLTLLVTRLSGGNIYVLKVLACHSEEMWCTESHPVTVEMFNTPEKPYSLVPENTSLQFNWKAPLNVNLIRFWVELQKWKYNEFYHVKTSCSQGPAYVCNITNLQPYTSYNVRVVVVYKTGENSTSLPESFKTKAGVPNKPGIPKLLEGSKNSI--QWEKAEDNGCRITYYILEIRKSTSNNLQNQNLRWK----------------------MTFNGSCSSVCTWKSKNLKGIFQFRVVAANNLGFGEYSGISENIILVGDDFWIPETSFILTIIVGIFLVVTIPLTFVWHRRLK--NQKSAKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSG-EIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGP----LLTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSP--RIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIYKSRDEANNSGVINESFEGEDGDVIC-LNSDDIMPVALMETKNREGLNYMVLATECGQGEEKSEGPLGSQESESCGLRKEEKEPHADKDFCQEKQVAYCPSGKPEGLNYACLTHSGYGDGSD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HQU1-1", "uniprot_id": "A0AC58HQU1_DANRE", "id": "A0AC58HQU1-1", "name": "Tyrosine-protein kinase receptor", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNGSELKCQTPRSGFKQCS--------------------------NAICQN----------------VACEL--------------------AAPYASWIG--------SHSISLTWESLN----QSDVVFVPQWTSPSLSGIWAQAENVTE-----------------------SSYTVEQLEPYTYYTFR-VWAVIAETQ--ACSPASPWYQTKPFGLPS-SPSIENVESISGESVEVRWTPPEKPRGPILGFNLNLTSNKHKISAATGGNVFSN--TFYPTFHNTTYRISIAAVNEEGQGSVAEASITTPAQVGQDGGRWVFASRWSSLRMREEDADFFTTAQCLSDSRIEGNITGVAVHYNSNHVYFS----EGSRIWVKGAGNLTDHSDLKLLHT----APLEVTALTVDWLYLRIYYASGGRIHYCGLDDCLS-------PVDTNVNLSSDAVNIIADPYNGWLYMLLSTGIYRSPLPDVSSQQQEISHIIKMPSVSNFVVSFPNKRIVYHDRSDQTLNATSLDG-LFPITLYTNVNFEAN---------SIVYEDNFFMLTNGYAVYKQVGQSQVPTFFEFAMDCDIIHSENGGFDNLCYFSTSAQLYPVPRKPKDLQVLFGSDKAYVYWNKPE----SMMGA--------------SPSAWQNWTYAINCTMNG--LVVMSIREVTSTYATVPDLQSSQHYNVTVRACSPGG-CSRSLSYEGTTLHPADEPPYIAAASDGDILKQDLDNIEFMEQIVSLIGDVKDMDWYNSTIYWTNSSGHINWFDLNNRSLSVMTMPSTPVHAEALAFDWLGQYLYWSCNT-NQICRGSTSGQAVEIFLQADQKILSLVIDSLNAAIYWTTETSVEACRLDGEGFQLLDKLSVFSGKEVAGVTLNMIEGNLYWLVQDGSLLNLYRVNISGDRMQKSKAVEFAKWTTSQIFDHQVSYYSERLVWLDEN-KQLRIQELNQNNSVLMSSNNTLTAFSVVQKMLKPLPDGFVSPPVVIPPAVS--KIVLVGNASFFQIHWE-PSSVDYGTVFYCVVSKEVWKNLDPLPN---MFPTRYCHPVNTFTETVINVTRFKPGAELNITITPFSYWGKGKSTETILITPAG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSDTDKTLIIAIVS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VAVGVTLIILILAVVIWQRHHKKKDHGKAKQPSSVQIHPDVELEYVRGLVG---LENGCFAISNTPSRAEIESLPVFPRDCLKLQRLLGSGAFGEVYEGVTVGSQINGVEPERKVAIKTLQKDASDYEKTEFLKEAHLMSQFNHPNILRLLGVCLLNEPHYLILELMEGGDLRSYLRGARPTNNHKE----LLSLSSLLDISLDAATGCAYLERMHFVHRDIAARNCLVSVRTYTDPE-RVVKIGDFGLARDVYKNDYYRKKGEGLLPVRWMSPESLTDGIFNKYSDVWAFGVLLWEILTLGKLPYPTYTNHEVLSYISTGGRLSSPAGCPQRLYNLMMSCWSKQPADRPNFQFLEETMRKLRNYEADKRAN--QTDGADGHVNQAYLGDEEEVCAGVEEDEDLETGLSPVLSNEGLNYLMYRAES----------LNSVQSDSSNGRED------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13368-1", "uniprot_id": "7LESS_DROME", "id": "P13368-1", "name": "Protein sevenless", "aln": "MTMFWQQNVDHQSDEQDKQAKGAAPTKRLNISFNVKIAVNVNTKMTTTHINQQAPGTSSSSSNSQNASPSKIVVRQQSSSFDLRQQLARLGRQLASGQDGHGGISTILIINLLLLILLSICCDVCRSHNYTVHQSPEPVSKDQMRLLRPKLDSDVVEKVAIWHKHAAAAPPSIVEGIAISSRPQSTMAHHPDDRDRDRDPSEEQHGVDERMVLERVTRDCVQRCIVEEDLFLDEFGIQCEKADNGEKCYKTRCTKGCAQWYRALKELESCQEACLSLQFYPYDMPCIGACEMAQRDYWHLQRLAISHLVERTQPQLERAPRADGQSTPLTIRWAMHFPEHYLASRPFNIQYQFVDHHGEELDLEQEDQDASGETGSSAWFNLADYDCDEYYVCEILEALIPYTQYRFRFELPFGENRDEVLYSPATPAYQTPPEGAPISAPVIEHLMGLDDSHLAVHWHPGRFTNGPIEGYRLRLSSSEGNATSEQLVPAGRGSYIFSQLQAGTNYTLALSMINKQGEGPVAKGFVQTHSARNEKPAKDLTESVLLVGRRAVMWQSLEPAGENSMIYQSQEELADIAWSKREQQLWLLNVHGELRSLKFESGQMVSPAQQLKLDLGNISSGRWVPRRLSFDWLHHRLYFAMESPERNQSSFQIISTDLLGESAQKVGESFDLPVEQLEVDALNGWIFWRNEESLWRQDLHG-----RMIHRLLRIRQPGWFLVQPQHFIIHLMLPQEGKFLEISYDGGFKHPLPLPPPSNGAGNGPASSHWQSFALLGRSLLLPDSGQLILVEQQG----QAASPSASWPLKNLPDCWAVILLVPESQPLTSAGGKPHSLKALLGAQAAKISWKEPERNPYQ------------------SADAARSWSYELEVLDVAS-QSAFSIRNIRGPIFGLQRLQPDNLYQLRVRAINVDGEPGEWTEPLAARTWPLGPHRLRWASRQGSVIHTNELGEGLEVQQEQLERLPGPMTMVNESVGYYVTGDGLLHCINLVHSQWGCPISEPLQHVGSVTYDWRGGRVYWTDLARNCVVRMDPWSGSRELLP--VFEANFLALDPRQGHLYYATSSQLSRHGSTPDEAVTYYRVNGLEG-SIASFVLDTQQDQLFWLVKGSGALRLYRAPLTAGGDSLQMIQQIKGVFQAVPDSLQLLRPLGALLWLERSGRRARLVRLAAPLDVMELPTPDQASPASALQLLDPQPLPPRDEGVIPMTVLPDSVRLDDGHWDDFHVRWQPSTSGGNHSVSYRLLLEFGQRLQTLDLSTPFARLTQLPQAQLQLKISITPRTAWRSGDTTRVQLTTPPVAPSQPRRLRVFVERLATALQEANVSAVLRWDAPEQGQEAPMQALEYHISCWVGSELHEELRLNQSALEARVEHLQPD---QTYHFQVEARVAATGAAAGAASHALHVAPEVQAVPRVLYANAEFIGELDLDTRNRRRLVHTASPVEHLVGIEGEQRLLWVNEHVELLTHVPGSAPAKLAR--MRAEVLALAVDWIQRIVYWAELDATAPQAAIIYRLDLCNFEGKILQGERVWSTPRGRLLKDLVALPQAQSLIWLEYEQGSPRNGSLRGRNLTDGSELEWATVQPLIRLHAGSLEPGSETLNLVDNQGKLCVYDVARQLCTASALRAQLNLLGEDSIAGQLAQDSGYLYAVKNWSIRAYGRRRQQLEYTVELEPEE-VRLLQAHNYQAYPPKNCLLLPSSGGSLLKATDCEEQRCLLNLPMITASEDCPLPIPGVRYQLNLTLARGPGSEEHDHG----VEPLGQWLLGAGESLNLTDLLPFTRYRVSGILSSFYQKKLALPTLVLAPLELLTASATPSPPRNFSVRVLSPRELEVSWLPPEQLRSESVYYTLHWQQELDGENVQDRREWEAHERRLETAGTHRLTGIKPGSGYSLWVQAHATPTKSNSSERLHVRSFAELPELQLLELGPYSLSLTWAGTPDPLG-SLQLECRSSAEQLRRNVAGNHTKMVVEPLQPRTRYQCRLLLGYAATPGAPLYHGTAEVYETLGDAPSQPGKPQLEHIAEEVFRVTWTAARGNGAPIALYNLEALQARSDIRRRRRRRRRNSGGSLEQLPWAEEPVVVEDQWLDFCNTTELSCIVKSLHSSRLLLFRVRARSLEHGWGPYSEESERVAEPFVSPEKRGSLVLAIIAPAAIVSSCVLALVLVRKVQKRRLRAKKLLQQSRPSIWSNLSTLQTQQQLMAVRNRAFSTTLS--DADIALLPQINWSQLKLLRFLGSGAFGEVYEGQLKTEDSEEPQ---RVAIKSLRKGAS--EFAELLQEAQLMSNFKHENIVCLVGICFDTESISLIMEHMEAGDLLSYLRAARATSTQEPQPTAGLSLSELLAMCIDVANGCSYLEDMHFVHRDLACRNCLVTESTGSTDRRRTVKIGDFGLARDIYKSDYYRKEGEGLLPVRWMSPESLVDGLFTTQSDVWAFGVLCWEILTLGQQPYAARNNFEVLAHVKEGGRLQQPPMCTEKLYSLLLLCWRTDPWERPSFRRCYNTLHAIS----TDLRRTQMASATADTVVSCSRPEFKVRFDGQPLEEHREHNERPEDENLTLREVPLKDKQ----------LYANEGVSRL----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : . .:: : .* . . : * ::: * :. : *: . * : . . :: * *:* * ** . : . **.:* *:* * * * :* * :: . . . : * * * . *** *:.*.* *. : : * .* * :::: :*: *:*. *:. : * : :. : : * * : .. :::.:: ..: ::: * : : . :: .:*:: . ::.***: *:*: . . . :: .*. **::: .::* * :::. * :. * : ** . *:. .. :::.:. : . . : : : . * . :*:.:..*:*: * : *. * ...* :.*:* :: . : :: . : **. * : *** . .: * * :..: . . * *.:: : : . : . . . :::::* * :**: : : * . ::. :.:*. . :*::* .:. : :.* .: ...*: :. *:***:.. :.** . : . :: : . : *.*:: : .: .* : *.* * : : *: . *:: *: ..: . * * : . : .. .. :. :: * : * : : . . ::: . ..: : : : . :: ..: * : * :* :: : * .:: :* ** : . *.* :************ :**:*:*:*.:: * *:*:**:***:*:* **: :*:*: *. :*:* **.*** :*** ** :. *:* .*: :.:* :.** *** ***:***:*.*****: : * **********::** *****.**********:**.* **:*.. ****:**:* *******: **.: .* :** ::. ****. * *.: *:.*: ** :* :**.* : :: : . . . : . : :: .. *. : : * . : ", "identical_positions": 250, "similar_positions": 375, "identity": "9.39%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020507-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A4A8-1", "uniprot_id": "D4A4A8_RAT", "id": "D4A4A8-1", "name": "Inversin", "aln": "MNISENVLSTGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSRRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLSTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHAKLLIKHDSNIGIPDVEGKIPLHWAANHKDASAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNLTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTVPSDSQGATPLHYAAQSNFAVLHYHGPDVPHHCAVSNKVFLQETVKVFLTHPSVRDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLDNDAQVDATDVMKHTPLFRACEMGHRDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAAFKIQAVYKGYKVRKAFRDRKNLLMKHEQLRKDAAAKKREEENKRKEAEQ-KGQPDTDPPR------PQVLPCPPSPQNEPSRQSAAPSKQPPASHTVQSPDPEQGR-PAGQCPGRASHRD--CSSDLQGTASRKPSESPREHCRGASAGVHPRSCEDGDSYRHQGTSSAEKCRGETSGEHQRCEQGPSRARQPVSTGSAGPAEKGEDSSPAITSASQRDRPRKPSKRQDGAPRSRGASQKRRTHQLR-DRCSPAGSSRPGSAKAEVARADQSSVHHDTPRNKVTQDKLVGGVSSDVPLSTEELGSGCQ-----KLYEDLCASPENNVAHGPRPGQSVNIHLLPVEQRLLIIQRERSRKELFRRKNKAAAVIQRAWRSYQLRKHLSRLLHLKQLGARDVLRCTQLCAALLLQVWRKELELKFPKSISVSRTSKSPSKGMSAAKSARHSVLRQIYGCSQEGKVHHPIRSPKVPPVLHLSS-----VNSLQSIHLD-SSGRSKKFSYNLQPASQSKNKPKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89019-1", "uniprot_id": "INVS_MOUSE", "id": "O89019-1", "name": "Inversin", "aln": "MNISEDVLSTGSSLASQVHAAAVNGDKGALQRLIVGNSALRDKEDRFGRTPLMYCVLADRVDCADALLKAGADVNKTDHSRRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLSTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHAKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNLTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFA----------------------ETVKVFLQHPSVKDDSDLEGRTSFMWAAGKGNDDVLRTMLSLKSDIDINMSDKYGGTALHAAALSGHVSTVKLLLDNDAQVDATDVMKHTPLFRACEMGHRDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAAFKIQAVYKGYKVRKAFRDRKNLLMKHEQLRKDAAAKKREEENKRKEAEQQKGQLDTDPPRSHCSSSAPVLPCPPSPQNEGSKQDATPSKQPPASHTVQSPDPEHSR-LPGRCPGRASQGD--SSIDLQGTASRKPSETPIEHCRGPSACVHPRSWEGGNSSKNQGTSSVEKRRGETNGKHRRCEEGPSSARQPLCTGSGRPAEKGEDSSPAVASASQQDHPRKPNKRQDRAARPRGASQKRRTHQLR-DRCSPAGSSRPGSAKGEVACADQSSLHRHTPRSKVTQDKLIGGVSSGLPLSTEASRSGCK-----QLYEDICASPETGVAHGPPPGQCMNIHLLPVEQRLLIIQRERSRKELFRRKNKAAAVIQRAWRSYQLRKHLSRLLHLKQLGAREVLRCTQVCTALLLQVWRKELELKFPKSISVSRTSKSPSKGSSATKYARHSVLRQIYGCSQEGKGHHPIKSSKAPAVLHLSS-----VNSLQSIHLD-NSGRSKKFSYNLQPSSQSKNKPKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y283-1", "uniprot_id": "INVS_HUMAN", "id": "Q9Y283-1", "name": "Inversin", "aln": "MNKSENLLFAGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFA----------------------ETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAAFKIQAVYKGYKVRKAFRDRKNLLMKHEQLRKDAAAKKREEENKRKEAEQQKGRRSPDSCR------PQALPCLPSTQDVPSRQSRAPSKQPPAGNVAQGPEPRDSRGSPGGSLGGALQKEQHVSSDLQGTNSRRPNETAREHSKGQSACVHFRPNEGSDGSRHPGVPSVEKSRGETAGDE-RCAKGKGFVKQPSCIRVAGPDEKGEDSRRAAASLPPHDSHWKPSRRHDTEPKAKCAPQKRRTQELRGGRCSPAGSSRPGSARGEAVHAGQNPPHHRTPRNKVTQAKLTGGLYSHLPQSTEELRSGARRLETSTLSEDFQVSKETDPAPGPLSGQSVNIDLLPVELRLQIIQRERRRKELFRKKNKAAAVIQRAWRSYQLRKHLSHLRHMKQLGAGDVDRWRQESTALLLQVWRKELELKFPQTTAVSKAPKSPSKGTSGTKSTKHSVLKQIYGCSHEGKIHHPTRSVKASSVLRLNS-----VSNLQCIHLLENSGRSKNFSYNLQSATQPKNKTKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8UVC1-1", "uniprot_id": "INVS_DANRE", "id": "Q8UVC1-1", "name": "Inversin", "aln": "----MAMLLPQN--PSQVHAAAVNGDKNTLHKLIT-ESALRDSEDQFGRTPLMYCVLADRLDCAEVLLKAGAGINKTDHSQRTALHLAAQKGNVRFMKLLLSRHADWRLKDLEEMTPLHLASRHSSSKPLSLLLKHMAPGEVDTQDRNKQTALHWSAFYNHPEHVKLLIKHDSNIGIPDSEGKIPLHWAAHNKHPNATRTVRCILEAAPTESLLNWQDYEGRTPLHFAVADGNEAVVEVLTSYEGCSVTAYDNLFRTPLHWAALLGHAKIVHLLLERNKSGMIPSDSQGATPLHYGAQSNFA----------------------DTVAVFLKHHSVRDEPDLEGRTAFMWAAGKGSNDVIKIMLDLKKDIDINMTDKYGGTALHAAALSGHVSTVRLLLEQGGMVDPLDVMKHTPLFRACEMGHRDVILTLIKGGARVDLVDIDGHSALHWAALGGNAEVCEVLMENGISPNLQDQAGRTPLQCAAYAGYINCMALLIQHDADPNIQDKEGRTALHWSCNNGYLDAVKLLLGCGAFPNHMEHTEERYTPLDYALLGEHQELTQFLLEHGALSIAAIQDIAASSIQALYKGYKVRRAFRERKKLLMRHEQLRKDAAKKR--EEERRREAEQQLSFAEAGQKQ-------RVLLAAVGVEKLSLDEAEQRVKDSVAAKGHKHKKSSSAH-----------------NSQSRREKPSRAERRTREPETSDAPSIRSLPPVTPMSTKKCPVTREEVCVRETFGPD---------TGISLNCGSANERRSPAGSSRPGSAKPVHTGTHVAPGHMETTPTPKPRPSTTGAHSKNASQDTPQHNETQTTSKGNKPISEHKP-TGSQPSNNTSVTRQKEKRQEKETHREKDKRSRTE--------GDKQTVREKQKGTG---IERAKERLMGRTRKKLAEKEKEKKKDGTCSKNQAAVVIQRAWRRSCVRGRIRKVLCRSLKGVESAEATALL--IQLLWEWPVLHDHTHRKPSDVQAPPTRIAGKKSSVLQNIYGAAPSKRGTSLRAAALKTQSQSQSQVLLDLSLRTHKQLSAVECVNLVDSVSQAKQFSYHLRPSSGASQSSQN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . . .************.:*::**. :***:*.**:**************:***:.******.:******:************ *******:*:*:* ***********::** *.* *:****.**********:**********:**:***.************** **********::*...*.:******:*************************** :**:******.*.:*:******************:************ :************.****** :** *** * **:*:.******:********.:**:: **.**.******:********************:***::.. **. ****************:*** ************* **** **********:**::*:** *.**:** ***********.*******:*::::*************************:****. .****:**:.**************::*: **:**************** .***:*******:***:**:***:********* *: **::*:**** . ... : .* . . :. : *:. *.: : .. .: . : : . :... . * . :. :: . . :: .. * ** * . . . . .. .* . :: . : . : : . .: ... ::. . .: :* .. :::.: : :.. * .:.: : . . : * . * . *. . * : : *: : :.:. :*: **:**.******* :* :: :: . *. .. ** * : .. :. *. ... : *.. :.. . * * .. :. . : :* *. :. ::.::* . .::*:***:*:.:: ..:..: ", "identical_positions": 518, "similar_positions": 258, "identity": "47.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020507-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P84889-1", "uniprot_id": "VANG2_RAT", "id": "P84889-1", "name": "Vang-like protein 2", "aln": "MDTESQYSGYSYKSGHSRSSRK--------------------HRDR-------RDRHRSKSRDGS-RGDKS---VTIQAPGEPLLDNE---STRGDERDDNWGETTTVVTG-TSEHSISHDDLTRIAKDMED-SVPLDCSRHLGVAAGAILALLSFLTPLAFLLLP--------------PLLWREELEPCGTACEGLFISVAFKLLILLLGSWALFFRRPKASLPRVFVLRALLMVLVFLLVISYWLFYGVRILD---------ARERSYQGVVQFAVSLVDALLFVHYLAVVLLELRQLQPQFTLKVVRSTDGASRFYNVGHLSIQRVAVWILEKYYHDFPVYNPALLNLPKSVLA---KKVSG-FKVYSLGEENSTNNSTGQSRAVIAAAARRRDNSHNEYYYEEAEHERRVRKRRARLVVAVEEAFTHIKRLQEEEQ----KNPREVMDPREAAQAIFASMARAMQKYLRTTKQQPYHTMESILQHLEFCITHDMTPKAFLERYLAAGPTIQYHKERWLAKQWTLVSEEPVTNGLKDGIVFLLKRQDFSLVVSTKKVPFFKLSEEFVDPKSHKFVMRLQSETSV---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZD4-1", "uniprot_id": "VANG2_MOUSE", "id": "Q91ZD4-1", "name": "Vang-like protein 2", "aln": "MDTESQYSGYSYKSGHSRSSRK--------------------HRDR-------RDRHRSKSRDGS-RGDKS---VTIQAPGEPLLDNE---STRGDERDDNWGETTTVVTG-TSEHSISHDDLTRIAKDMED-SVPLDCSRHLGVAAGAILALLSFLTPLAFLLLP--------------PLLWREELEPCGTACEGLFISVAFKLLILLLGSWALFFRRPKASLPRVFVLRALLMVLVFLLVISYWLFYGVRILD---------ARERSYQGVVQFAVSLVDALLFVHYLAVVLLELRQLQPQFTLKVVRSTDGASRFYNVGHLSIQRVAVWILEKYYHDFPVYNPALLNLPKSVLA---KKVSG-FKVYSLGEENSTNNSTGQSRAVIAAAARRRDNSHNEYYYEEAEHERRVRKRRARLVVAVEEAFTHIKRLQEEEQ----KNPREVMDPREAAQAIFASMARAMQKYLRTTKQQPYHTMESILQHLEFCITHDMTPKAFLERYLAAGPTIQYHKERWLAKQWTLVSEEPVTNGLKDGIVFLLKRQDFSLVVSTKKVPFFKLSEEFVDPKSHKFVMRLQSETSV---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULK5-1", "uniprot_id": "VANG2_HUMAN", "id": "Q9ULK5-1", "name": "Vang-like protein 2", "aln": "MDTESQYSGYSYKSGHSRSSRK--------------------HRDR-------RDRHRSKSRDGG-RGDKS---VTIQAPGEPLLDNE---STRGDERDDNWGETTTVVTG-TSEHSISHDDLTRIAKDMED-SVPLDCSRHLGVAAGATLALLSFLTPLAFLLLP--------------PLLWREELEPCGTACEGLFISVAFKLLILLLGSWALFFRRPKASLPRVFVLRALLMVLVFLLVVSYWLFYGVRILD---------ARERSYQGVVQFAVSLVDALLFVHYLAVVLLELRQLQPQFTLKVVRSTDGASRFYNVGHLSIQRVAVWILEKYYHDFPVYNPALLNLPKSVLA---KKVSG-FKVYSLGEENSTNNSTGQSRAVIAAAARRRDNSHNEYYYEEAEHERRVRKRRARLVVAVEEAFTHIKRLQEEEQ----KNPREVMDPREAAQAIFASMARAMQKYLRTTKQQPYHTMESILQHLEFCITHDMTPKAFLERYLAAGPTIQYHKERWLAKQWTLVSEEPVTNGLKDGIVFLLKRQDFSLVVSTKKVPFFKLSEEFVDPKSHKFVMRLQSETSV---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8UVJ6-1", "uniprot_id": "VANG2_DANRE", "id": "Q8UVJ6-1", "name": "Vang-like protein 2", "aln": "MDNESQYSGYSYKSSHSRSSRK--------------------HRDR-------RDRHRSKSRDSSSRGDKS---VTIQAPGEPLLDAE---STRGDDRDDNWGETTTVVTG-TSEHSVSNEDLTRASKELED-SSPLECRRFAGPIVSGVLGLFALLTPLAFLLLP--------------QLLWRDSLEPCGTPCEGLYVSLAFKLLVLLISSWALFLRPSRSTLPRFFVFRCLLMALVFLFVASYWLFYGVRVLE---------PRERDYRGIVGYAVSLVDALLFIQYLALVLLEVRHLRPAFCLKVVRTTDGASRFYNVGHLSIQRAAVWVLDHYYTDFPVYNPALLNLPKSILS---KKMSG-FKVYSLGEENSTNNSTGQSRAMIAAAARRRDNSHNEYYYEEAEMDRRVRKRKARLVVAVEEAFTHIKRLQDDEAAASPKHPREVMDPREAAQAIFAPMARAMQKYLRTTRQQPYHSMESIISHLQFCITHNMTPKAFLERYLTPGPTMQYQRENGRGRQWTLVSEEPVTAALRQGLVFSLRRLDFALVVTVTPLPFLNLGEEFIDPKSHKFVMRLQSETSV---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KEN4-1", "uniprot_id": "A0A0B4KEN4_DROME", "id": "A0A0B4KEN4-1", "name": "Vang-like protein", "aln": "MENESVKSEHSGRSRRSRNHNNNGGGGGGGGGGGGGSVNNGYHRERDRSRHSHRSTHSSKSAKGFQRGDMAPYQTSVNMTGDGSHDGQEVIEVQILPQDENWGENTTAVTGNTSEQSISMEDINNMWHRESDKGFSFACRRYVESSFYFLLGCGAFFSPVAMVVMPYVGFFPSAFDHPEITQTVRTQLLACSEQCKGQLVSLAARLLLLAIGLWAVFMRRTSATMPRIFLYRALVLLLVTICTFAYWLFYIVQVTNGAKIVVETGGDAVDYKSLVGYATNFVDTLLFIHYVAVVLLELRHQQPCYYIKIIRSPDGVSRSYMLGQLSIQRAAVWVLQHYYVDFPIFNPYLERIPISVSKSQRNKISNSFKYYEVDGVSNSQQQS-QSRAVLAANARRRDSSHNERFYEEHEYERRVKKRRARLITAAEEAFTHIKRIHNEPA------PALPLDPQEAASAVFPSMARALQKYLRVTRQQPRHTFESILKHLAHCLKHDLSPRAFLEPYLTESPVMQSEKERRWVQSWSLICDEIVSRPIGNECTFQLIQNDVSLMVTVHKLPHFNLAEEVVDPKSNKFVLKLNSETSVXHHHNAPPINTPTHSNQTQSSYLHVFV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 221, "similar_positions": 191, "identity": "35.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020509-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZGQ5-1", "uniprot_id": "NEK8_RAT", "id": "D3ZGQ5-1", "name": "Serine/threonine-protein kinase Nek8", "aln": "-----------------------------------------------------------------------------------------------------MEKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCN-SLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPLSHIMA--QPLCIRALLN--IHTDVGSVRMRRAEKCLTPGTPMAPGSTGSRATSARCRG--VPRGPVRPAIPPPLSS-------VYAWGGGLSIPLRLPMPNTEVVQVAAGRTQKAGVTRSGRLILWEAPPLGTGGGTLLPGAVELPQPQFVSRFLEGQSGVTIKHVACGDLFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLALSADGELFAWGRGDGGRLGLG-TRESHNCPQQVPMVPGQE-AQRVVCGIDCSMILTSPGRVLACGSNRFNKLGLDCLSLEEEPVPHQQVEEALSFTPLGSAPLDRETLLCVDLGTAHSAAVTASGACYTFGSNQHGQLGTSSRRVSRAPCRVQGLEGIKMVMVACGDAFTVAIGAEGEVYSWGKG---------------------ARGRLGR-----------------------------RDEDAGLPRPVQLDETHPYTVTSVSCCHGNTLLAVRSVTDEPVPP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZR4-1", "uniprot_id": "NEK8_MOUSE", "id": "Q91ZR4-1", "name": "Serine/threonine-protein kinase Nek8", "aln": "-----------------------------------------------------------------------------------------------------MEKYERIRVVGRGAFGIVHLCLRKADQKLVILKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCN-SLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPLSHIMA--QPLCIRALLN--IHTDVGSVRMRRAEKSLTPGPPIASGSTGSRATSARCRG--VPRGPVRPAIPPPLSS-------VYAWGGGLSSPLRLPMLNTEVVQVAAGRTQKAGVTRSGRLILWEAPPLGAGGGTLLPGAVELPQPQFVSRFLEGQSGVTIKHVACGDLFTACLTDRGIIMTFGSGSNGCLGHGNLTDISQPTIVEALLGYEMVQVACGASHVLALSTDGELFAWGRGDGGRLGLG-TRESHNCPQQVPVAPGQE-AQRVVCGIDSSMILTSPGRVLACGSNRFNKLGLDHLSLDEEPVPYQQVEEALSFTPLGSAPLDQEPLLCVDLGTAHSAAITASGDCYTFGSNQHGQLGTSSRRVSRAPCRVQGLEGIKMVMVACGDAFTVAVGAEGEVYSWGKG---------------------TRGRLGR-----------------------------RDEDAGLPRPVQLDETHPYMVTSVSCCHGNTLLAVRSVTDEPVPP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86SG6-1", "uniprot_id": "NEK8_HUMAN", "id": "Q86SG6-1", "name": "Serine/threonine-protein kinase Nek8", "aln": "-----------------------------------------------------------------------------------------------------MEKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCN-SLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPLSHIMA--QPLCIRALLN--LHTDVGSVRMRRAEKSVAP------SNTGSRTTSVRCRG--IPRGPVRPAIPPPLSS-------VYAWGGGLGTPLRLPMLNTEVVQVAAGRTQKAGVTRSGRLILWEAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLALSTERELFAWGRGDSGRLGLG-TRESHSCPQQVPMPPGQE-AQRVVCGIDSSMILTVPGQALACGSNRFNKLGLDHLSLGEEPVPHQQVEEALSFTLLGSAPLDQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAESEVYSWGKG---------------------ARGRLGR-----------------------------RDEDAGLPRPVQLDETHPYTVTSVSCCHGNTLLAVRSVTDEPVPP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90XC2-1", "uniprot_id": "NEK8_DANRE", "id": "Q90XC2-1", "name": "Serine/threonine-protein kinase Nek8", "aln": "-----------------------------------------------------------------------------------------------------MEKYEKTKVVGRGAFGIVHLCRRRTDSALVILKEIPVEQMTRDERLAAQNECQVLKLLSHPNIIEYYENFLEDKALMIAMEYAPGGTLADYIQKRCN-SLLDEDTILHSFVQILLALYHVHNKLILHRDLKTQNILLDKHQMIVKIGDFGISKILVSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLILNMLNLDPSKRPQLNEIMA--HAICIRPLLN--LYTDIGNVKMRRIEKPLSNVQAGPHGRPGGWITSTRTRGGLSSLTSSKMMHPLPLFS-------VYTWGSGISTPLRLPMLNTEVIQVSLGRTQKMGVTKSGRLITWEAPSVGSGE-PTLPGAVEQMQPQFISRFLEGQSGVTIKSVSCGDLFTTCLTDRGIIMTFGSGSNGCLGHGNFNDVTQPKIVEALLGYELVQVSCGASHVLAVTNEREVFSWGRGDNGRLGLA-TQDSHNCPQQVSLPADFE-AQRVLCGVDCSMIMSTQHQILACGNNRFNKLGLDKVSGTEEPSSFCQVEEVHLFQLVQSAPLNTEKIVYIDIGTAHSVAVTEKGQCFTFGSNQHGQLGCSHRRSSRVPYQVSGLQGIT--MAACGDAFTLAIGAEGEVYTWGKG---------------------ARGRLGR-----------------------------KEEDFGIPKPVQLDESHAFTVTSVACCHGNTLLAVKPFFEEPGPK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC32-1", "uniprot_id": "Q9VC32_DROME", "id": "Q9VC32-1", "name": "", "aln": "MKKFRAKASSLPIFNGRITDATTLTTSSLQLPLGQNTQRKQSTCTRVLPTVFTITDGTTGAASTSLAEAMSSSKAQMPNRQESLLQLSVPRETGVGVAGPELANYEKVRVVGQGSFGIAILYRRKSDGHQIVFKQINLSELSPPGRDLAMNEVDVFSKLHHPNIVSYLGSFIKDNTLLIEMEYADGGTLAQIIAERQGKLHFPERYIIAVFEQISSAINYMHSENILHRDLKTANVFLNR-RGIVKIGDFGISKIMNTKIHAQTVLGTPYYFSPEMCEGKEYDNKSDIWALGCILGEMCCLKKTFAASNLSELVTKIMAGNYTPVPSGYTSGLRSLMSNLLQVEAPRRPTASEVLVYWIPLIFRSLGKNKGYSYEDDVGGPGSDQLTAPVPAAAYSNVSMELELPTAQTETKQLMIADTAAPHEILEKRSVLYQLKAFGTCFSMAPIQLPPKAVIVDVAMSDSHFVVVNEDGSAYAWGEGTHGQLGLTALEAWKHYPSR------MESVRNYHVVSACAGDGFTILVTQAGSLLSCGSNAHLALGQDEQRNYHSPKLIARLADVRVEQVAAGLQHVLALSREGAVYVWGTSTCGALGLGNYQQQQKFPQKILLSHVKTKPSKIYCGPDTSAVLFANGELHVCGSNDYNKLG------------FQRSAKITAFKKVQLP----HKVTQACFSSTHSVFLVEGGYVYTMGRNAEGQRGIRHCNSVDHPTLVDSVKSRYIVKANCSDQCTIVASEDNIITVWGTRNGLPGIGSTNCGLGLQICTPNMELELGNNTAAFTNFLASVYKSELILEPVDILALFSSKEQCDRGYYVQVHDVYPLAHSVLVLVDTTTPLISSYEGDYPHL-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :**: :***:*:***. * *::* :::*:* :.::: * * ** :*:. * ***::.* .*::*::*:* **** *****: * :* . : * *: * ** *: ::*.. ******** *::*:: : :***********: :* :* **:*** *:***:**** *::*********:* *:..**::* *:**. ** ***:*.::*:.. *:. **.*: .:*.::..:** ..::. .: :*.* : :: ..* :: : . . : * : . : ::* :. . :: :::*: . :: *...* * . * . * . . . :*. . : ...** ** :*: * ::: **.:: .**:.. : .*.:: * . .: **:.* .****:: : :: ** . * ***. ::.:. **:: : ..:: ** * * :: . .**.* :**** . : : * : . . : :.::**. :. * :*:* * .** * . * *..::. . *.* *:. . :. : **. . .**. .*: . **:.: :. : : . .* * : * ", "identical_positions": 189, "similar_positions": 229, "identity": "21.85%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020513-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q921A4-1", "uniprot_id": "CYGB_RAT", "id": "Q921A4-1", "name": "Cytoglobin", "aln": "MEKVPGDMEIERRERNEELSEAERKAVQATWARLYANCEDVGVAILVRFFVNFPSAKQYFSQFKHMEDPLEMERSPQLRKHACRVMGALNTVVENLH---DPDKVSSVLALVGKAHALKHKVEPMYFKILSGVILDVIAEEFANDF-PVETQKAWTKLRGLIYSHVTAAYKEVGWVQQVPNTTTLPATLPSSGP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CX80-1", "uniprot_id": "CYGB_MOUSE", "id": "Q9CX80-1", "name": "Cytoglobin", "aln": "MEKVPGDMEIERRERSEELSEAERKAVQATWARLYANCEDVGVAILVRFFVNFPSAKQYFSQFRHMEDPLEMERSPQLRKHACRVMGALNTVVENLH---DPDKVSSVLALVGKAHALKHKVEPMYFKILSGVILEVIAEEFANDF-PVETQKAWAKLRGLIYSHVTAAYKEVGWVQQVPNTTTPPATLPSSGP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWM9-1", "uniprot_id": "CYGB_HUMAN", "id": "Q8WWM9-1", "name": "Cytoglobin", "aln": "MEKVPGEMEIERRERSEELSEAERKAVQAMWARLYANCEDVGVAILVRFFVNFPSAKQYFSQFKHMEDPLEMERSPQLRKHACRVMGALNTVVENLH---DPDKVSSVLALVGKAHALKHKVEPVYFKILSGVILEVVAEEFASDF-PPETQRAWAKLRGLIYSHVTAAYKEVGWVQQVPNATTPPATLPSSGP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8UUR3-1", "uniprot_id": "CYGB1_DANRE", "id": "Q8UUR3-1", "name": "Cytoglobin-1", "aln": "ME---GDGGVQLTQSPDSLTEEDVCVIQDTWKPVYAERDNAGVAVLVRFFTNFPSAKQYFEHFRELQDPAEMQQNAQLKEHGQRVLNALNTLVENLR---DADKLNTIFNQMGKSHALRHKVDPVYFKILAGVILEVLVEAFPQCFSPAEVQSSWSKLMGILYWQMNRVYAEVGWENSKK--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VF15-1", "uniprot_id": "Q9VF15_DROME", "id": "Q9VF15-1", "name": "", "aln": "------------------MNSDEVQLIKKTWEIPVATPTDSGAAILTQFFNRFPSNLEKFP-FRDVP-LEELSGNARFRAHAGRIIRVFDESIQVLGQDGDLEKLDEIWTKIAVSHIPR-TVSKESYNQLKGVILDVLTAACSLDE---SQAATWAKLVDHVYGIIFKAIDDDGNAK-----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. : :: * * : *.*:*.:** .*** : * *:.: *:. ..::: *. *:: .:: :: * * :*:. : :. :* : .*. :: * ****:*:. . . :*:** . :* : . : * : ", "identical_positions": 31, "similar_positions": 56, "identity": "15.98%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020513-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P6V0-1", "uniprot_id": "G6PI_RAT", "id": "Q6P6V0-1", "name": "Glucose-6-phosphate isomerase", "aln": "--------MAALTRNPEFQKLLEWHRANSANLKLRELFEADPERFNHFSLNLNT-NHGHILLDYSKNLVNKEVLHMLVDLAKSRGVEAARDNMFSGLKINSTEDRAVLHVALRNRSNRSIMMDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKAITDIINIGIGGSDLGPLMVTEALKPYSKGGPRVWFVSNIDGTHIAKTLANLNPESSLFIIASKTFTTQETITNAETAKEWFLQAA-KDPSAVAKHFVALSTNTDKVKEFGIDPKNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQLLSGAHWMDQHFMKTPLDKNAPVLLALLGIWYINFYGCETHAMLPYDQYMHRFAAYFQQGDMESNGKYITKSGARVDYQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRNGLHHKILLANFLAQTEALMKGKSPEEARKELQAAGKSPEELEKLLPHKVFEGNRPTNSIVFTKLTPFILGALIAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSSAVTSHDSSTNGLIGFIKLQRDTKID", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06745-1", "uniprot_id": "G6PI_MOUSE", "id": "P06745-1", "name": "Glucose-6-phosphate isomerase", "aln": "--------MAALTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLNT-NHGHILVDYSKNLVNKEVMQMLVELAKSRGVEAARDNMFSGSKINYTENRAVLHVALRNRSNTPIKVDGKDVMPEVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPRVWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAA-KDPSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQLLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQGDMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAGKSPEDLEKLLPHKVFEGNRPTNSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSAVTSHDSSTNGLISFIKQQRDTKLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06744-1", "uniprot_id": "G6PI_HUMAN", "id": "P06744-1", "name": "Glucose-6-phosphate isomerase", "aln": "--------MAALTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLNT-NHGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAA-KDPSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAGKSPEDLERLLPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQVTSHDASTNGLINFIKQQREARVQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PDD1-1", "uniprot_id": "A0A8M1PDD1_DANRE", "id": "A0A8M1PDD1-1", "name": "Glucose-6-phosphate isomerase", "aln": "---------MGLNNDPNFIKLEQWYKSSAGNLNMRQMFEADADRFNKFSLQLST-DDGDLLLDFSKNLINEDVMSLLFDMARSVGVEAAREQMFAGEKINFTEGRAVLHTALRNRSNTPIIVDGKDVMPEVNRVLEQMKSFCHKVRSGAWKGFSGKSITDVVNIGIGGSDLGPLMVTEALKPYSKGGPNVWFVSNIDGTHMAKTLAQLNAETTLFIIASKTFTTQETITNAETAREWFLQAA-KDKSAVAKHFVALSTNAPKVKEFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALHIGFDNFEQLLSGAHWMDNHFRSAPLEQNAPVILALLGVWYVNFFQAETHALLPYDQYMHRFAAYFQQGDMESNGKYITKSGTRVNYHTGPIVWGEPGTNGQHAFYQLIHQGTRLIPADFLIPAQSQHPIRDNLHHKILMANFLAQTEALMRGKTSDEAKKELQASGLSGDSLEKLLPHKVFQGNKPSNSIIFKKLTPFMLGALVAMYEHKIFVQGVMWNINSYDQWGVELGKQLAKKIEPELQDDAEVHSHDSSTNGLIGFFKKNRF----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P52029-1", "uniprot_id": "G6PI_DROME", "id": "P52029-1", "name": "Glucose-6-phosphate isomerase", "aln": "----MAGPLPPLNQEAAFQKLQEYYDSKGKDLNIKDLFVKDSKRFSKYSLRLHTQNDGEILLDYSKNRINDEVWDLLLTLAKVRRVNAARDAMFSGQHINITENRAVLHTALRNRGTDPVLVDDKDVMPDVRAELAHMKEFTNMVISGVWRGCTGKQITDVVNIGIGGSDLGPLMVTEALKPYGKG-LHSHFVSNIDGTHLAEVLKKVNYETTLFIVASKTFTTQETITNATSAKTWLLEHS-KEPESVAKHFVALSTNKEKVTEFGIDSTNMFGFWDWVGGRYSLWSAIGLSICLSIGFENFEQLLDGAHFMDNHFKTTPFEKNAPVILALLGVWYSNFFKAETHALLPYDQYLHRFAAYFQQGDMESNGKFVSKSGKPVKYSTGPIVWGEPGTNGQHAFYQLIHQGTRLIPCDFIAPAQTHNPIAGGKHHKILLSNFLAQTEALMAGKTVDEARTELSKAGLCGNELDNLLPHKVFVGNRPTNSIVVKKVSPFTLGALIALYEHKIFVQGIIWDINSFDQWGVELGKQLAKAIEPELDHCNEVSTHDSSTNGLINFIKANWK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12709-1", "uniprot_id": "G6PI_YEAST", "id": "P12709-1", "name": "Glucose-6-phosphate isomerase", "aln": "MSNNSFTNFKLATELPAWSKLQKIYESQGKTLSVKQEFQKDAKRFEKLNKTFTNYDGSKILFDYSKNLVNDEIIAALIELAKEANVTGLRDAMFKGEHINSTEDRAVYHVALRNRANKPMYVDGVNVAPEVDSVLKHMKEFSEQVRSGEWKGYTGKKITDVVNIGIGGSDLGPVMVTEALK-HYAGVLDVHFVSNIDGTHIAETLKVVDPETTLFLIASKTFTTAETITNANTAKNWFLSKTGNDPSHIAKHFAALSTNETEVAKFGIDTKNMFGFESWVGGRYSVWSAIGLSVALYIGYDNFEAFLKGAEAVDNHFTQTPLEDNIPLLGGLLSVWYNNFFGAQTHLVAPFDQYLHRFPAYLQQLSMESNGKSVTRGNVFTDYSTGSILFGEPATNAQHSFFQLVHQGTKLIPSDFILAAQSHNPIENKLHQKMLASNFFAQAEALMVGKDEEQVKAEGATGG--------LVPHKVFSGNRPTTSILAQKITPATLGALIAYYEHVTFTEGAIWNINSFDQWGVELGKVLAKVIGKELDNSSTISTHDASTNGLINQFKEWM-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . : ** : : *.:: * : .**.: . : . : ..:*.*:*** :..:: *. :*: * . *: ** * :** **.*** *.*****.. .: :*. :* *:* * :**.* . * ** *:* :** ***::***********:******* : * :********:*:.* :. *::**::******* ****** :*: *:*. : :: . :****.***** :* :****. *** * .*******:*******:.* :*:::** :*.**. :*:** :*::.* *:: .**.:** * : .:** : *:***:***.**:** .****** :::.. ..: **.*::***.**.**:*:**:****::**.**: ..*:::** *:*:* :**:**:**** ** ::.: * .* *:***** **:*:.**: *::* ****:* *** *.:* :*:***:********* *** * **: : :**:******. :* ", "identical_positions": 256, "similar_positions": 160, "identity": "45.07%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020516-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRJ3-1", "uniprot_id": "D3ZRJ3_RAT", "id": "D3ZRJ3-1", "name": "Putative nucleotidyltransferase MAB21L1", "aln": "------MIAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLNEMDNRYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWPGPNRVAEVKAEGFNLLSKECHSLAGKQ---SSAESDAWVLQFAEAENRLQMGGCRKKCLSILKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70299-1", "uniprot_id": "MB211_MOUSE", "id": "O70299-1", "name": "Putative nucleotidyltransferase MAB21L1", "aln": "------MIAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLNEMDNRYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWPGPNRVAEVKAEGFNLLSKECHSLAGKQ---SSAESDAWVLQFAEAENRLQMGGCRKKCLSILKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13394-1", "uniprot_id": "MB211_HUMAN", "id": "Q13394-1", "name": "Putative nucleotidyltransferase MAB21L1", "aln": "------MIAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLNEMDNRYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWPGPNRVAEVKAEGFNLLSKECHSLAGKQ---SSAESDAWVLQFAEAENRLQMGGCRKKCLSILKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYB4-1", "uniprot_id": "MB211_DANRE", "id": "Q6NYB4-1", "name": "Putative nucleotidyltransferase MAB21L1", "aln": "------MIAAQAKLVYHLNKYYNEKCQSRKAAISKTIREVCKVVSDVLKEVEVQEPRFISSLNEMDNRFEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWPGPNRVAEVKAEGFNLLSKECYSLNGKQ---SSAESDAWVLQFAEAENRLLLGGCRKKCLSLLKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDENCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y106-1", "uniprot_id": "MB21L_DROME", "id": "Q9Y106-1", "name": "Protein mab-21-like", "aln": "MLVPPDMMAAQTRMVYQMNRFCTERVQARMYKTATAIREICKIVQDILKEVELQEPRFISSLVECNGRFEGVEVISPNEFEIVLYLNQMGVFNFVDDGTLPGCAVLKLSDGRKRSMSLWVEFITASGYLSSRKIRARFQTLVAQACDKSVYRDMVKMVGDTSEVKLRIRERFVVQITPAFKCSGIWPRSAAHWPVPHLPWPHPNIVAEVKTEGFDLLSKESVIMQNKNNNAASMEGDAWVLSFFEAENRLLQGGCRRRCLSMLKTLRDRHLDLPGNPISAYHLKNLLLYECEKHPRDFEWDEGCIADRINGIFLQLISCLQYRRCPHYFLPALDMFKGKSPSALEQAAKQVWRLTRELLTNANAFEKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9U3W6-1", "uniprot_id": "MAB21_DROME", "id": "Q9U3W6-1", "name": "Protein mab-21", "aln": "MLVPSDMIAAQSKMVYQMNKYCADRVQVRKAQIHKQIQEVCRIVQDVLKEVEVQEPRFISSLNDYNGRFQGLEVISPTEFEIIIYLNQMGVLNFVDDGTLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQACDKCAYRDIVKMIADTTEVKLRIRERIIVQITPAFKCAGLWPRSASHWPLPGIPWPHPNIVAEVKTEGFNMLSKECIALQGKN---SAMEGDAWVLSFTDAENRLLQGASRRRCLSILKTLRDRHLDLPGNPVTSYHLKTLLLYECEKHPREMEWEENCIADRINGIFLQLISCLQCRRCPHYFLPNMDLFKGKSPGALENAAKQVWRLTRIMLTNVRCLEEL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:***:::**::*:: :: * * . *:*:*::*.*:*****:********* : :.*::*:*****.***:::*******:******:*******************************:****:********* **. ***:***:.**:*******:* :*********:*:*****:***:* :*** ** *****:***::****. : .*: :: *.*****.* :***** *..*::***:*********:***:*:. **:*.*: ********: :*:*.*:.**:***:******** ********* :*:*:**. .***:****.***:* :*** ..:*:*", "identical_positions": 237, "similar_positions": 89, "identity": "64.4%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020529-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96SF7-1", "uniprot_id": "TBX15_HUMAN", "id": "Q96SF7-1", "name": "T-box transcription factor TBX15", "aln": "MSERRRSAVALSSRAHAFSVEALIGSNKKRKLRDWEEKGLDLSMEALSPAGPLGDTEDAAAHGLEPHPDSEQSTGSDSEVLTERTSCSFSTHTDLASGAAGPVPAAMSSMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSPTTSSTGTPSPSASSHLLSPSCSPPTFHLAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYPGLSDSGYNRLQS--GTTSATQPSETFMPQRTPSLISG-----------IPTPPSLPGNSKMEAYGGQLGSFPTSQFQYVMQAGN---------AASSSSSPHMFGGS--HMQQSSYNAFSLHNPYNLYGYNFPTSPRLAASPEKLSASQSTLLCSSPSNGAFGERQYLPSGMEHSMHMISPSPNNQQATNTCDGRQYGAVPGSSSQMSVHMV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O70306-1", "uniprot_id": "TBX15_MOUSE", "id": "O70306-1", "name": "T-box transcription factor TBX15", "aln": "MSERRRSAVALSSRAHAFSVEALIGSNKKRKLRDWEEKGLDLSMEALSPAGPLGDTDDPATHGLEPHPDSEQSTGSDSEVLTERTSCSFSTHTDLASGAAGPVPAAMSSMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSPTTSSTGTPSPSASSHLLSPSCSPPTFHLAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYPGLSDSGYNRLQS--GTASATQPSETFMPQRTPSLISG-----------IPTPPSLPSNSKMEAYGGQLGSFPTSQFQYVMQAGN---------AASSSSSPHMFGGS--HMQQSSYNAFSLHNPYNLYGYNFPTSPRLAASPEKLSASQSTLLCSSPSNGAFGERQYLPTGMEHSMHMISPSTNNQQATNTCDGRQYGAVPGSASQMSVHMV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2R8QEJ0-1", "uniprot_id": "A0A2R8QEJ0_DANRE", "id": "A0A2R8QEJ0-1", "name": "", "aln": "MSDRRRSAAALSSRAHAFSVEALIGTNKKRKLRGWEEKELELSMESLASNGQLGDGEDPAN-CLDIDPDSEASPGSDGEGLAERTSCSFGSPADLTSAACDPSPS--ASMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKIVGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSELSPTKPVPTGEGVKTFSFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTNMQKQQGGSTGTSPTTSSTGTPSPSGATHLLSPSCSPPTFHLAPNTFNVGCRESQLCNLGLSEYPACARSNMAALQGYGGLADGSYGRLQTTGGAVASAQASESFLPQRTSSLIAAGMQGGAHGSLATGNSGSGSGGGKMDAYGSQLASFPASQLQYVMQAGASSASGSSASSGSSSSSAHMFSGSHHHVQQSTYNAFSLHNPYNLYGYNFPASPRLAASPEKP---QGGLLCSSSSAGAFAERQYLSNGGMDSMHMIGNPTGSQQGAGSCDGRQY----GSSSQMSMHMV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*****.****************:*******.**** *:****:*:. * *** :*.* *: .**** *.***.* *:*******.: :**:*.*..* *: :******************************************.******************************************************************************************************:********.*:*****.****************************************************************.************************.::*******************************.**:**.**********.* **:*..*.***: *:.:::*.**:*:****.***:. .. * ....**:***.**.***:**:******* :.*****.***.** *:***:******************:********** *. *****.* ***.*****..* .*****. ....**.:.:****** **:****:***", "identical_positions": 481, "similar_positions": 88, "identity": "76.84%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020529-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A1V6-1", "uniprot_id": "D4A1V6_RAT", "id": "D4A1V6-1", "name": "", "aln": "MAEKRRGSPCSMLSLKAHAFSVEALIGAEKQQQLQKKRRKLATEEAAGAVDDAGCSRGGGAREHRCTEADEDPAPPPPAAGSASGPARSCTDAERSCASRGPAGSCEDGFLQGASPLASPGGSPKGSPVPGLARPGTPLPAPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISFDKLKLTNNELDDQGHIILHSMHKYQPRVHIIRKDCGDDLSPIKPVPSGEGVKAFSFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDIPGIPKQGNTSSSALLPGTGNGVPAAHPHLLSGSSCSSPAFHLGPNTSQLCSMAPADYSACARSGLALNRYSTSL-AETYNRLTNQSSETFAPPRTPSYVSVSS-PSVNMSMGGTDGDTFSCPQTSLSMQISGMS---PQLQYIIPSPSSNAFAANQTHQGSYNTFRLHSPCALYGYNFSTSPKLAASPEKIVSSQGSFLGSSPSGTMTDRQMLPPVEGVHLLGSGNQQSFFDSRTLGSLTLSSSQVSAHMV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPZ6-1", "uniprot_id": "TBX18_MOUSE", "id": "Q9EPZ6-1", "name": "T-box transcription factor TBX18", "aln": "MAEKRRGSPCSMLSLKAHAFSVEALIGAEKQQQLQKKRRKLATEEAAGAVEDAGCSRSGGAGEHGCSEADEEAAAPPPAAGAASGPARSCADAERSCGSRGAAGSCEDGFLQGASPLASPGGSPKGSPVPGLARPGTPLPAPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDIPGIPKQGNTSSSALLQGTGNAVPATHPHLLSGSSCSSPAFHLGPNTSQLCSLTPADYSACARSGLALNRYSTSL-AETYSRLTNQSSETFAPPRTPSYVSVSSNPSVNMSMGGTDGDTFSCPQTSLSMQISGMS---PQLQYIMPSPSGNAFAANQTHQSSYNTFRLHSPCALYGYNFSTSPKLAASPEKIVSSQGSFLGSSPSGTMTDRQMLPPVEGVHLLSSGGQQSFFDSRTLGSLTLPSSQVSAHMV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95935-1", "uniprot_id": "TBX18_HUMAN", "id": "O95935-1", "name": "T-box transcription factor TBX18", "aln": "MAEKRRGSPCSMLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAAGAVDDGGCSRGGGAGEKGSSEGDEGAALPPPAG-ATSGPARSGADLER-----GAAGGCEDGFQQGASPLASPGGSPKGSPARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDIPGIPKQGNASSSTLLQGTGNGVPATHPHLLSGSSCSSPAFHLGPNTSQLCSLAPADYSACARSGLTLNRYSTSL-AETYNRLTNQAGETFAPPRTPSYVGVSSSTSVNMSMGGTDGDTFSCPQTSLSMQISGMS---PQLQYIMPSPSSNAFATNQTHQGSYNTFRLHSPCALYGYNFSTSPKLAASPEKIVSSQGSFLGSSPSGTMTDRQMLPPVEGVHLLSSGGQQSFFDSRTLGSLTLSSSQVSAHMV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PA62-1", "uniprot_id": "A0A8M1PA62_DANRE", "id": "A0A8M1PA62-1", "name": "", "aln": "MAEKRR-SPCTMS-LKAHAFSVEALIGTEK-------KRKLEEEDSENCFEEIN-------------EVPRMTESPQPSTGRTCPSTRSCE----------IDCTSDESPEPEDVLLDSPQPASQG--AQVLVQSAT--SSGEEMRVDLQGSDLWKRFHEIGTEMIITKAGRRMFPAMRVKIAGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKECGEELSPVKAVPTGDGVKAFSFTETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDIPGITKQGAAGS--------HGVVGSSAHLLSSSSCPSPTFHLGSGAGPVC-----DYSTCSRTSHPLHRYGPSLSADSYSRLTSPTADAFSTSRSSTYV------------SGTESEAFSCTQTGLPIQIHSMPSTTSQLQYLMPGHAHNAFSTNQSTQGSYNGFRLHNPYGLYGYNFSTSPRLATSPEKAAATQTSFLGSSPSGTLTDRQVLSTMDGLHMLSS-SQQNLFDSRTLG-LTSSSSQVTAHMA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****** ***:* *************:** :*** *:: ...:: . * . . * *: :. .:** .::. * ** :.:* . *.:..* .: : ******::*****************************:**********************************************************************************************:***:**::***:*.**:*:*******.****************************************************************.*** :.* :.* .: .****.***.**:****..:. :* ***:*:*:. .*:**..** *::*.***. :.::*:..*:.:** .**:.::***.**.*.:** .*. .****::*. : ***::**: *.*** ****.* .**********:**:**** .::* **********:****:*..::*:*:*.* .**.:******* ** .****:***.", "identical_positions": 374, "similar_positions": 125, "identity": "60.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020531-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UBC0-1", "uniprot_id": "HNF6_HUMAN", "id": "Q9UBC0-1", "name": "Hepatocyte nuclear factor 6", "aln": "MNAQLTMEAIGELHGVSHEPVPAPADLLGGSPHARSSVAHRGSHLPPAHPRSMGMASLLDGGSGGGDYHHHHRAPEHSLAGPLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSDKFPHHHHHHHHHHHPHHHQRLAGNVSGSFTLMRDERGLASMNNLYTPYHKDVAGMGQSLSP-LSSSGLGSIHN-----------SQQGLP--HYAHPGAAMPTDKMLTPNGFEAHHPAMLGRHGEQHLTPTSAGMVPINGLPPHHPHAHLNAQGH------GQLLGTAREPNPSVTGAQVSN-----GSNSGQ-MEEINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEHGK-DRGNTPKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELSTVSNFFMNARRRSLDKWQDEG-SSNSGNSSSSSS----TCTKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BF65-1", "uniprot_id": "A2BF65_DANRE", "id": "A2BF65-1", "name": "One cut domain family member", "aln": "MDGN-----MGEMSVHSHVELAH-------SQESRAMLHSR--DLTAAFPRPS-----LGGPVMGLESDHQSPTYDH------MATLGYSRDAPT--TCGSTYTTLTPLQPFD------DKF---HHHHHHPCLP------VSNVIGSFTLMREDRSLG--GNYYTSYGKDFG-LGQGLSPPLGSAGLDTAMHGYGTLGSQNGHSSQMLPGGHEVHMGSNGSNICRTVPDFVREMSPPSLG--AEHGVSHQLNKMDAHQHTPTYHHHLYNQSYQHHLPSQQASKLGELPSSSPSSSGSSLGREGMLAGSQNGSGGEEINTKDVAQRIITELKRYSIPQAIFAERVLCRSQGTLSDLLRNPKPWGKLKSGRETFKRMSRWLQEPEFQRMASLRLEACKRKEQEQSKVERNQGPKRTRLVFTDLQRRTLMAIFRENHRPTKDLQITISQQLGLELSTVSNFFMNARRRNLNRWAEEGRPSSTGSSGSSTASPAVTCSTA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.: :**: ** :. * .:*: : * .*..*.**. *.* * : .*: : :* .*: : ::*. : :**********: *** ****** * ..** *******::*.*. .* **.* **.. :**.*** *.*:**.: : *.* ** * .* *: .. .*: .. *. ** .*: :: * . : *.:* * : :: * .. ** ...** :*:.:.. **:.*. ******:***** **************:********************.*********:** :**********::*** ********:.* :*.: **:.******:***** ***:**:**:*:**************************.*::* :** .*.:*.*.**:: **:.*", "identical_positions": 228, "similar_positions": 115, "identity": "45.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020531-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P41738-1", "uniprot_id": "AHR_RAT", "id": "P41738-1", "name": "Aryl hydrocarbon receptor", "aln": "-MSSGANITYASRKRRKPVQKTVKPVPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSTPADRSRGQDQCRAQ-VRDWQD------LQEGEFLLQALNGFVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCTDSAQGVDETHGLPQPAVYYTPDQLPPENTAFMERCFRCRLRCLLDNSSGFLAMNFQGRLKYLHGQNKKGKDGALLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGQLILGYTEVELCNKGSGYQFIHAADMLHCAESHIRMIKTGESGMTVFRLLAKHSRWRWVQSNARLIYRNGRPDYIIATQRPLTDEEGREHLQKRSMTLPFMFATG-----------EAVLYEISSPFSPIMDPLPIRTKSNTSRK-----------------------------------------------DWAPQSTPSKDSFHPNSLMSALIQQDESIYLCPPSSP---APLDSHFLMDS---------------------------------------------------MSECGSWQGSFAVASNEALLKHEEIRHTQDVNLTLSGGPSELFPDNKNND-----------------------------LYSIMRNLGIDFEDIR---------SMQNEEFFRTDS--SGEVDFKDIDITDEILTYVQDSLNNSTLLNSACQQQ-PVSQHLSCMLQERLQLEQQQQLQQQHPTQTLEPQRQLCQVEVPQHELGQKTKHMQVNGMFASWNPAPPVSFSCPQQERKHYSLFSGLQGTAQEFPYKSEVDSMPYTQNFAPCNQSLLPEHSKGTQLDFPGRDFERSLHPNASNLEDFVSCLQVPENQRHG-INSQSAMVSPQAYYAGAMSMYQCQAGPQHTPVDQMQYSPEIPGSQAFLSKFQSPSILNEAYSADLSS-IGH-LQTAAHLP---RLAEAQPLPDITPSGFL------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30561-1", "uniprot_id": "AHR_MOUSE", "id": "P30561-1", "name": "Aryl hydrocarbon receptor", "aln": "-MSSGANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSTPADRNGGQDQCRAQ-IRDWQD------LQEGEFLLQALNGFVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNP----DSAQGVDEAHGPPQAAVYYTPDQLPPENASFMERCFRCRLRCLLDNSSGFLAMNFQGRLKYLHGQNKKGKDGALLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGQLILGYTEVELCTRGSGYQFIHAADMLHCAESHIRMIKTGESGMTVFRLFAKHSRWRWVQSNARLIYRNGRPDYIIATQRPLTDEEGREHLQKRSTSLPFMFATG-----------EAVLYEISSPFSPIMDPLPIRTKSNTSRK-----------------------------------------------DWAPQSTPSKDSFHPSSLMSALIQQDESIYLCPPSSP---APLDSHFLMGS---------------------------------------------------VSKCGSWQDSFAAAGSEAALKHEQIGHAQDVNLALSGGPSELFPDNKNND-----------------------------LYNIMRNLGIDFEDIR---------SMQNEEFFRTDSTAAGEVDFKDIDITDEILTYVQDSLNNSTLMNSACQQQ-PVTQHLSCMLQERLQLEQQQQLQQP-PPQALEPQQQLCQMVCPQQDLG--PKHTQINGTFASWNPTPPVSFNCPQQELKHYQLFSSLQGTAQEFPYKPEVDSVPYTQNFAPCNQPLLPEHSKSVQLDFPGRDFEPSLHPTTSNLD-FVSCLQVPENQSHG-INSQSTMVSPQAYYAGAMSMYQCQPGPQRTPVDQTQYSSEIPGSQAFLSKVQSRGIFNETYSSDLSS-IGHAAQTTGHLH---HLAEARPLPDITPGGFL------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35869-1", "uniprot_id": "AHR_HUMAN", "id": "P35869-1", "name": "Aryl hydrocarbon receptor", "aln": "MNSSSANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSSPTERNGGQDNCRAANFREGLN------LQEGEFLLQALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCTESGQGIEEATGLPQTVVCYNPDQIPPENSPLMERCFICRLRCLLDNSSGFLAMNFQGKLKYLHGQKKKGKDGSILPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGRIVLGYTEAELCTRGSGYQFIHAADMLYCAESHIRMIKTGESGMIVFRLLTKNNRWTWVQSNARLLYKNGRPDYIIVTQRPLTDEEGTEHLRKRNTKLPFMFTTG-----------EAVLYEATNPFPAIMDPLPLRTKNGTSGK-----------------------------------------------DSATTSTLSKDSLNPSSLLAAMMQQDESIYLYPASSTSSTAPFENNFFNES---------------------------------------------------MNECRNWQDNTAPMGNDTILKHEQIDQPQDVN-SFAGGHPGLFQDSKNSD-----------------------------LYSIMKNLGIDFEDIR---------HMQNEKFFRNDF--SGEVDFRDIDLTDEILTYVQDSLSKSPFIPSDYQQQQSLALNSSCMVQEHLHLEQQQQHHQK--QVVVEPQQQLCQK----------MKHMQVNGMFENWNSNQFVPFNCPQQDPQQYNVFTDLHGISQEFPYKSEMDSMPYTQNFISCNQPVLPQHSKCTELDYPMGSFEPSPYPTTSSLEDFVTCLQLPENQKHG-LNPQSAIITPQTCYAGAVSMYQCQPEPQHTHVGQMQYNPVLPGQQAFLNKFQN-GVLNETYPAELNN-INN-TQTTTHLQPLHHPSEARPFPDLTSSGFL------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A9V8-1", "uniprot_id": "A0AB13A9V8_DANRE", "id": "A0AB13A9V8-1", "name": "", "aln": "-MSSSN--IYASRKRRKPVQKSVK-QPLTCVKSNPSKRHRDRMNEVLASLAREIPFPQEIVSTLDKLTILRLSVSYLRAKSHFKITLNSKSSSQ-------QANNTKQAQE------QPEGEFLLQAINGFLLVVTSSGIVFYVSSNIEDYLGFHQSDVIHQSVYELIHTEDRHEFQRQLHWALNPGFTPDSRQLVQASP--DASRTCYSPEQLSLENSTCLERNFICRLRCLLDSTSGFLAVNFQGRLKFLYGQNESTGDGKRIPPQLALFALACPLQPPSILEIRTKNLMFKTKYKLDFTPIACDTNWNFVLGYTEAELCNSGSGYQFIHAADMMYCAEGHMRMMRTGKTGLTVFRLLTKQNRWVWVQSNGKLVYKNGQPDCIITSHRVITAEEGEENLRNRAMMLPFNFTTG-----------DAVLCAMNCP-----------TSSDPASS-----------------------------------------------DGNTQPKTTR-TVNPDSLLVSLLKQPKSIYLSPADER--------SVLVQS---------------------------------------------------LGNK-DLDGIYSINSQESVSVSRSCPFKQESVFSSER--------DDSCE-----------------------------ILNFMGSLGISLEDLK---------FLQHEDLFINMD---LDSHNDMADLSDDILSHVQQSLKT--------KMDCTVSKNTQGNMKEQELIRNPAQTIIP--NDSCDTITLLSQEQQMTFITDKTEPKIQLT-QIQPYTPQKGITYLQIDPHEHQDTRPQSYNGTGITLPKSSHSTIQTISQHLQFSNLPPFHEQ-VCEALRSP--QVCGNMAEVIDSDIQQVSPLFPPELQPSGCFYLERPILDPKLCTSSSQQLSSSQ----TTEGEPVEFT--TQDLEDLINDMNGVGERNNYSGLDRGMDIRSSLDQQAYIG----TGSPQRNEPPTYAAYV------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1JIM6-1", "uniprot_id": "E1JIM6_DROME", "id": "E1JIM6-1", "name": "", "aln": "--MSQLGTVYATKRRRRNGKSLKPPPKDGVTKSNPSKRHRERLNAELDLLASLLPFEQNILSKLDRLSILRLSVSYLRTKSYFQVVMHKDKEDNGVLPHIHAHDGYRTRELGAFEHGLLDGDMFLQALNGFLMILTCEGEVFFATHSIESYLGFHQSDIVHQSVYELVHSEDREELQRQLLWNSFLPADMSSMQ---------------LAETLAPDKALYLERSFTVRFRCLLDNTSGFLRLDIRGRIKVLHGQNRKTEE-----PPLALFAYCTPFGPPSLLEIPHKENMFKSKHKLDFSLVSMDQRGKHILGYADAELVNMG-GYDLVHYDDLAYVASAHQELLKTGASGMIAYRYQKKDGEWQWLQTSSRLVYKNSKPDFVICTHRQLMDEEGHDLLGKRTMDFKVSYLDTGLASTYFSEADQLVVPPSTSPTAHALPPPVTPTRPNRRYKTQLRDFLSTCRSKRKLQQQNQPQTQQTSPLGGQVGSPAPAVAVEYLPDPAAAVAAAYSNLNPMYTTSPYASAADNLYMGSSMPANAFYPVSENLFHQYRLQGAVGGYYTDYPHSGAPASAYVANGFLSYDGYAIASKADEKWQETGKYYSGYSSGYGSPTSTPQQIPLKTPKSSPQVMEVISCSSDGPSPVGGATPNGVGSVTPKVELAGTTAAAAAGQDPYERQTVLMWGTTHSSGVPLNSHGGRTGAGNPASPQRSTPLGNGLGYASANNNNNDLEPATAAKWNGTKELPGKSGSASTPESYQMQHDDSGLYSASSHTTSPQQQQQQQLQQSQRGVGSNVSAPSSSLTSTGTDQQAVHPSSCHQQQQQQQQQHHHAHPHPHSHHHHHHHHHHETAHQHSSEIILTTHHQQQSQQQQQSLAGYPLHHQLVGVGSGSPPPQPPVALSRSPTTLPAVSSLLNGSASAGGASDIPYQQLAIVSAPLVICAEEVGGGVSSIGRKSSKQQQSLQHLQQQQSLQQQQHAIYQQQHHHSQHHPHHQLLYPANITAHTALAYAPPTAGGAYADGSPLLSFSEVTNTLLNQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **:::**: :. *********:*:* * ** :** *:::..**:*::*********:**.*.:.::. .. : :*:::***:***::::* .. **:.: .*:.****:***::*******:*:*** *:**** * .* * .: :. ::: :** * *:*****.:**** ::::*::* *:**:.. : * ***** . *: ***:*** *: :*::*:****: :. * . . :***::.** . * **:::* *: : *..* .:::** :*: .:* *...* *:*:..:*:*:*.:** :* ::* : *** : * :* : . : : *: . * * . . * . : ..:* . . ..:*: .. .: . . . : . . .. : . : . . *: ::. *.. : . . . . . . : . . . . * . : . . . : : ... . *: : : * . . . : . : : .: : .: . : . . : : .. . : : . : : ..: ", "identical_positions": 156, "similar_positions": 222, "identity": "15.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020708-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07996-1", "uniprot_id": "TSP1_HUMAN", "id": "P07996-1", "name": "Thrombospondin-1", "aln": "MGLAWGLGVLFLMHVCGTNRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFRIEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALERKDHSGQVFSVVSNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELDVPIQSVFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCS-SSTSVLLTLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRKVTEENKELANEL-RRPPLCYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRC-WPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPNLPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYNHNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHNPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDNDGIPDDKDNCRLVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRFQMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDDDYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNALWHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYDKTYAGGRLGLFVFSQEMVFFSDLKYECRDP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35441-1", "uniprot_id": "TSP1_MOUSE", "id": "P35441-1", "name": "Thrombospondin-1", "aln": "MELLRGLGVLFLLHMCGSNRIPESGGDNGVFDIFELIGGARRGPGRRLVKGQDLSSPAFRIENANLIPAVPDDKFQDLLDAVWADKGFIFLASLRQMKKTRGTLLAVERKDNTGQIFSVVSNGKAGTLDLSLSLPGKQQVVSVEEALLATGQWKSITLFVQEDRAQLYIDCDKMESAELDVPIQSIFTRDLASVARLRVAKGDVNDNFQGVLQNVRFVFGTTPEDILRNKGCS-SSTNVLLTLDNNVVNGSSPAIRTNYIGHKTKDLQAICGLSCDELSSMVLELKGLRTIVTTLQDSIRKVTEENRELVSEL-KRPPLCFHNGVQYKNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRC-WPSDSADDGWSPWSEWTSCSATCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQRRSRLCNNPTPQFGGKDCVGDVTENQVCNKQDCPIDGCLSNPCFAGAKCTSYPDGSWKCGACPPGYSGNGIQCKDVDECKEVPDACFNHNGEHRCKNTDPGYNCLPCPPRFTGSQPFGRGVEHAMANKQVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPNLPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYNHNPDQADTDKNGEGDACAVDIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHNPDQLDSDSDLIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDNDGIPDDRDNCRLVPNPDQKDSDGDGRGDACKDDFDHDNVPDIDDICPENFDISETDFRRFQMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDDDYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNALWHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGYIRVVMYEGKKIMADSGPIYDKTYAGGRLGLFVFSQEMVFFSDMKYECRDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QL35-1", "uniprot_id": "F1QL35_DANRE", "id": "F1QL35-1", "name": "Thrombospondin-1", "aln": "-MKSTAIFLLLMLWNCESARVAESRDDNSVYDLFELVQVPRKNHGVTLVKGDDPYSPAYKILNPDLIPPVPESAFRDLIDSIHAEKGFLLLVNFKQFKRTRGSLLTVEKNDGSGPVFEIVSNGKANTLDIVFSTENKQQVVSIEEADLAVGHWKNITLFVQEDRVQFYVGCEEVNVAELDASIHTILTQEIPGVAKMRIGKGAVKDRFMGVLQNVRFVFGTTLEAILRNKGCQNSAMTDIITLDN-PINGSSPAIRTDYTGHKTKDLQMICGFSCEDLAAMFKELKGLGVVVQELSNELRKVTDDKNMLMNQMGIRAGVCLHNGIVHKNKEEWTVDDCTECTCQNSATVCRKISCPLIPCANATVPDGECCPRCGTPSDSAEDGWSPWSEWTHCSVSCGRGIQQRGRSCDRINNNCEGTSVQTRDCYLQECDKRFKQDGSWSHWSPWSSCSVTCGAGVITRIRLCNSPTPQMDGKDCQGEGRQTERCEKSPCPINGGWGPWSPWDTCSVTCGGGVQNRKRLCNNPVPKHGGKECVGDAKVSQICNKQACPVDGCLSSPCFEGAQCTSFPDGSWKCGKCPTGYTGNGINCKDVNECKEVPDACFEFNGVHRCENTVPGYNCLPCPTRYTGPQPFGRGVEDAAAKKQVCTPRNPCLDGSHDCNKNARCNYLGHFSDPMFRCECKPGFAGNGHICGEDTDLDGWPNADLVCVENATYHCKKDNCPNLPNSGQEDYDKDGIGDACDDDDDDDGIPDDRDNCPLVFNPRQYDYDRDDVGDRCDNCPYNSNPDQTDTDNNGEGDACAVDIDGDGILNEKDNCPYLYNVDQKDTDLDGVGDQCDNCPLEHNPDQLDSDSDRVGDKCDSNQDIDEDGHQNNLDNCPYIPNANQADHDKDGKGDACDYDDDNDGIPDEKDNCRLVFNPDQLDSDGDGRGDACKDDFDMDNVLDIYDVCPENFDISETDFRKFQMVPLDPKGTSQIDPNWVVRHQGKELVQTVNCDPGIAVGFDEFNSVDFSGTFFINTERDDDYAGFVFGYQSSSRFYVVMWKQITQTYWSSTPTKAQGYSGLSIKVVNSTTGPGEHLRNALWHTGDTPGQVRTLWHDPKNVGWKDFTAYRWHLTHRPRTGHIRVVMYEGKKIMADSGRIYDKTYAGGRLGLFVFSQEMVYFSDLKYECRDA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :*::: * : *:.** .**.*:*:*** .*:. * **** * ***::* :.:***.**:. *:**:*:: *:***::*..::*:*:***:**::*::* :* :*.:******.***: :: .**:***:*** **.*:**.*********.*:*:.*:::: ****..*::::*:::..:*::*:.** *:*.* ************* * *******. *: . ::**** :*********:* ******** ***:**::*::*. **:** .:* *.:.:****:::. * .:: *. :* ***: ::*:******.**** ****.*:*:*:***::**:************* *****:********** **.:**.********** :**.***:***** *::***********.*************** ************:***:** *:**.*:*: *:*..************** **********.*.******.*:.***:****.. .*:**** **:*****.*** *.:***:******** **.**:****:*.**:**********:.** ***:** *********.*:**.****:***.* *:****.***** **:*******:******:****:*******:**** ************* :**** ************************************:* *********: :** ******************* ****:***:********.**********:*** *:*****:***:************************ :**.**.******************:******************:*********::****** **** **************** *.* ** *:****.********:***:********* **********************:***:****:*************************************:**:**.:.**:********:*********************:************:::**********:*:***:**.**************** *********************:***:******.", "identical_positions": 866, "similar_positions": 221, "identity": "73.83%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020708-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q03350-1", "uniprot_id": "TSP2_MOUSE", "id": "Q03350-1", "name": "Thrombospondin-2", "aln": "-------MLWALALLALGIGPRASAGDHVKDTSFDLFSISNINRKTIGAKQFRGPDPGVPAYRFVRFDYIPPVNTDDLNRIVKLARRKEGFFLTAQLKQDRKSRGTLLVLEGPGTSQRQFEIVSNGPGDTLDLNYWVEGNQHTNFLEDVGLADSQWKNVTVQVASDTYSLYVGCDLIDSVTLEEPFYEQLEVDRSRMYVAKGASRESHFRGLLQNVHLVFADSVEDILSKKGCQHSQGAEVNTISEHTETLHLSPHITTDLVVQGVEKAQEVCTHSCEELSNMMNELSGLHVMVNQLSKNLERVSSDNQFLLELIGGPLKTRNMSACVQEGRIFAENETWVVDSCTTCTCKKFKTVCHQITCSPATCANPSFVEGECCPSCSHSADSDEGWSPWAEWTECSVTCGSGTQQRGRSCDVTSNTCLGPSIQTRTCSLGKCDTRIRQNGGWSHWSPWSSCSVTCGVGNVTRIRLCNSPVPQMGGKNCKGSGRETKPCQRDPCPIDGRWSPWSPWSACTVTCAGGIRERSRVCNSPEPQYGGKDCVGDVTEHQMCNKRSCPIDGCLSNPCFPGAKCNSFPDGSWSCGSCPVGFLGNGTHCEDLDECAVVTDICFSTNKAPRCVNTNPGFHCLPCPPRYKGNQPFGVGLEDARTEKQVCEPENPCKDKTHSCHKNAECIYLGHFSDPMYKCECQIGYAGDGLICGEDSDLDGWPNNNLVCATNATYHCIKDNCPKLPNSGQEDFDKDGIGDACDEDDDNDGVSDEKDNCQLLFNPRQLDYDKDEVGDRCDNCPYVHNPAQIDTDNNGEGDACSVDIDGDDVFNERDNCPYVYNTDQRDTDGDGVGDHCDNCPLMHNPDQIDQDNDLVGDQCDNNEDIDDDGHQNNQDNCPYISNSNQADHDNDGKGDACDSDDDNDGVPDDRDNCRLVFNPDQEDSDGDGRGDICKDDFDNDNVPDIDDVCPENNAITETDFRNFQMVPLDPKGTTQIDPNWVIRHQGKELVQTANSDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQVTQTYWEDKPSRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTEGQVRTLWHDPKNIGWKDYTAYRWHLIHRPKTGYMRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQEMVYFSDLKYECRDA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35442-1", "uniprot_id": "TSP2_HUMAN", "id": "P35442-1", "name": "Thrombospondin-2", "aln": "-------MVWRLVLLALWVWPSTQAGHQDKDTTFDLFSISNINRKTIGAKQFRGPDPGVPAYRFVRFDYIPPVNADDLSKITKIMRQKEGFFLTAQLKQDGKSRGTLLALEGPGLSQRQFEIVSNGPADTLDLTYWIDGTRHVVSLEDVGLADSQWKNVTVQVAGETYSLHVGCDLIDSFALDEPFYEHLQAEKSRMYVAKGSARESHFRGLLQNVHLVFENSVEDILSKKGCQQGQGAEINAISENTETLRLGPHVTTEYVGPSSERRPEVCERSCEELGNMVQELSGLHVLVNQLSENLKRVSNDNQFLWELIGGPPKTRNMSACWQDGRFFAENETWVVDSCTTCTCKKFKTICHQITCPPATCASPSFVEGECCPSCLHSVDGEEGWSPWAEWTQCSVTCGSGTQQRGRSCDVTSNTCLGPSIQTRACSLSKCDTRIRQDGGWSHWSPWSSCSVTCGVGNITRIRLCNSPVPQMGGKNCKGSGRETKACQGAPCPIDGRWSPWSPWSACTVTCAGGIRERTRVCNSPEPQYGGKACVGDVQERQMCNKRSCPVDGCLSNPCFPGAQCSSFPDGSWSCGSCPVGFLGNGTHCEDLDECALVPDICFSTSKVPRCVNTQPGFHCLPCPPRYRGNQPVGVGLEAAKTEKQVCEPENPCKDKTHNCHKHAECIYLGHFSDPMYKCECQTGYAGDGLICGEDSDLDGWPNLNLVCATNATYHCIKDNCPHLPNSGQEDFDKDGIGDACDDDDDNDGVTDEKDNCQLLFNPRQADYDKDEVGDRCDNCPYVHNPAQIDTDNNGEGDACSVDIDGDDVFNERDNCPYVYNTDQRDTDGDGVGDHCDNCPLVHNPDQTDVDNDLVGDQCDNNEDIDDDGHQNNQDNCPYISNANQADHDRDGQGDACDPDDDNDGVPDDRDNCRLVFNPDQEDLDGDGRGDICKDDFDNDNIPDIDDVCPENNAISETDFRNFQMVPLDPKGTTQIDPNWVIRHQGKELVQTANSDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQVTQTYWEDQPTRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTPGQVRTLWHDPRNIGWKDYTAYRWHLTHRPKTGYIRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQEMVYFSDLKYECRDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6V3-1", "uniprot_id": "A0ACD6B6V3_DANRE", "id": "A0ACD6B6V3-1", "name": "Thrombospondin-2", "aln": "MILRSNLCLWPLLLLCIRALP--QDGLVEDESVFDLFKISGISRKTIGAKLFKGHDWDSPAYRFIRFDHIPAVSTPALHQILKQVQNNEGFVFVATMRQDKGSRGTLLGVEGPGG-LRQLEIVSNGRANTLDLVYMVKGSQNVVSFEDVDLSDSQWKNISLYVHGENAHLYVGCSLIDSVILDEPFYELLHPEGSQMFVAKGSIRENHFRGLLQNVQFLFDTPIENILRNKGCEIAKPEEVNVVNESTESVSVGTSISTNFIGEKEKIASDVCERSCEELSNMVQELKGLRIIVGNLIDGLQKVTEENTVMKEVLGNMKNIKDKRMCWQDGRLFEDKEDWVVDSCTKCTCQESKIVCHQITCPPVACASPTFLDGECCPLCLP-KDSEDGWSPWSEWTECTVTCGTGTQQRGRSCDATSNPCSGPSIQTRRCSLGKCDSRVRQDGGWSLWSPWSSCSVTCGEGQITRIRHCNSPVPQLGGKDCEGSGRETQKCEAKPCPIDGAWGPWSPWAVCSVTCGGGTRTRTRVCNSPRPQYGGKKCPGDSVDTNACNKQDCPVDGCLSNPCFGGVECTSSPDGSWECGPCPLGFRGNGKVCEDVNECDMVPDLCYKVGDSQRCVNTDPGFHCLPCPPRYKGNQPFGMGVEAAKLNKQVCEQENPCKEKTHNCHRSAECIYLGHFSEPMFKCECKIGYAGDGLICGEDSDLDGWPNQNLVCGANQSYHCKKDNCPKLPNSGQEDFDKDGQGDACDKDDDNDGIMDETDNCPLLYNPRQFDYDKDLVGDRCDNCPYEHNPAQIDTDGNGEGDACAVDIDGDEVLNENDNCPYMYNTDQKDTDMDGVGDQCDNCPLLHNPEQTDSDNDRVGDECDNNQDIDEDGHQNSLDNCPYIPNANQADHDKDGKGDACDSDDDNDGVPDDKDNCRLVPNKDQRDSDGDGRGDACKDDFDNDSIPDFMDVCPENDAISNTDFRKFQMVHLDPKGTAQIDPNWVVRHQGKELVQTANSDPGIAVGFDEFNAVDFSGTFYVNTDRDDDYAGFVFGYQSSGRFYVVMWKQITQTYWEDNPSKAIGISGVSLKVVNSTTGTGEHLRNALWHTGDTPGQVRTLWHDPKNIGWKDYTAYRWHLIHRPKTGFIRVVVYEGKQIMADSGPVYDQTFAGGRLGLFVFSQELVYFSDLKYECRDN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* * **.: * . * .:: ****.**.*.******* *:* * . *****:***:**.*.: * :* * :.:***.:.* ::** ****** :**** **:****** .:**** * :.*.::. :***.*:******::: * .:. *:***.****. *:***** *. : *:*:****: **.*********:::* .:*:** :***: .: *:*.:.* **:: :.. ::*: : : :** :*****.**::**.**:::*.:* ..*::*:.:* .: *::*. : :: * *:**:* ::* *******.***:: * :******.*.:**.*:*::***** * *.::*****:***:*:****:**********.***.* ******* ***.***:*:**:**** ************ *::**** *******:***:*:******: *: ****** *.*****:.*:***.** * *:******.****** * ** : : ***:.**:********* *.:*.* *****.**.**:** ***. ***::** :*.*:*:.... *****:************:****.*:*:* *: :***** *****:***.**: **********:**:****: ******************** ****.:* :*** *****:************* *****.******: **.*** **:**** ***** ********** *********.*******:******:*:**.*****:*****:*** *****:******:***:* * *** ***:****:***:*****. ******.*:******.**:*****.**********:****** * **.* ******* ********.:**: ******:**::****:**** ******:*******:************************.:***************************.*********:*******:*::* * **************************:* **********:************** ******::**:*:****:******:****:*************:************ ", "identical_positions": 800, "similar_positions": 237, "identity": "67.85%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020708-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JZH3-1", "uniprot_id": "A0A0G2JZH3_RAT", "id": "A0A0G2JZH3-1", "name": "Thrombospondin-3", "aln": "MPLVPEAGDASKVIGSSLFQPPPPSPPAAPPTPARSSVPPPPFCSCSPPSLFPSQSPCLPGVVNRLSGMEKPELWVALA-LLLCSYTCGS----QDLQVIDLLTVSESRQMAAVAEKVRTALLTAGDIYLLSTFRLPPKQGG----------VLFGLYSRQDN-------TRWLEASVVGKINKVLVRYQREDGKVHAVNLQQA-GLADGRTHTALLRLRGPSRPSPGLQLYVDCKLGDQHAGLP-------------ALAPIPPAEVSGLEIRTGQKAYLRMQGFVESMKIILGGSMARVGALS---ECPFQGDESIHN-------AVTSALQSILGEQTKALVTQLTLFNQILVELRDDIRDQVKEMSLIRNTIMECQVCGFHEQ------RSHCSPSPCFRGVDCMEVYEYPGYRCGPCPPGLRGNGTHCEDIDECAHADPCFLGSSCINTMPGFHCEACPQGYKGTRVSGVGIDYARAS--KQVCSDIDECNDGNNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCTPAR-TCHSPAHSPCHIHAHCLFERNGAVSCQCNVGWAGNGNVCGPDTDIDGYPDQALPCMDNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPKVPNPLQTDRDEDGVGDTCDSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECDSDDDNDGVPDYVPP---GPDNCRLVPNPNQKDSDGNGVGDVCEDDFDNDAVVDPLDVCPESAEVTLTDFRAYQTVILDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYWQATPFRAVAQPGLQLKAVTSISGPGEHLRNALWHTGHTPDQVRLLWTDPRNVGWRDKTSYRWRLLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCNDTVP----EDFEPFRRQLLQGRV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q05895-1", "uniprot_id": "TSP3_MOUSE", "id": "Q05895-1", "name": "Thrombospondin-3", "aln": "--------------------------------------------------------------------MEKPELWGVLALLLLCSYTCGS----QDLQVIDLLTVGESRQMVAVAEKIRTALLTAGDIYLLSTFRLPPKQGG----------VLFGLYSRQDN-------TRWLEASVVGKINKVLVRYQREDGKVHAVNLQQA-GLADGRTHTALLRLRGPSRPSPGLQLYVDCKLGDQHAGLP-------------ALAPIPPAEVSGLEIRTGQKAYLRMQGFVESMKIILGGSMARVGALS---ECPFQGDDSIHN-------AVTSALQSILGEQTKALVTQLTLFNQILVELRDDIRDQVKEMSLIRNTIMECQVCGFHEQ------RSHCSPSPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCDDINECAHADPCFPGSSCINTMPGFHCEACPPGYKGTRVSGVGIDYARAS--KQVCNDIDECNDGNNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCVPAR-TCHSPAHSPCHIHAHCLFERNGAVSCQCNVGWAGNGNVCGPDTDIDGYPDQALPCMDNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPKVPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECDGDDDNDGVPDYIPP---GPDNCRLVPNPNQKDSDGNGVGDVCEDDFDNDAVVDPLDVCPESAEVTLTDFRAYQTVILDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYWQATPFRAVAQPGLQLKAVTSISGPGEHLRNALWHTGHTPDQVRLLWTDPRNVGWRDKTSYRWRLLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCNDTVP----EDFEPFRRQLLQGRV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49746-1", "uniprot_id": "TSP3_HUMAN", "id": "P49746-1", "name": "Thrombospondin-3", "aln": "--------------------------------------------------------------------METQELRGALALLLLCFFTSAS----QDLQVIDLLTVGESRQMVAVAEKIRTALLTAGDIYLLSTFRLPPKQGG----------VLFGLYSRQDN-------TRWLEASVVGKINKVLVRYQREDGKVHAVNLQQA-GLADGRTHTVLLRLRGPSRPSPALHLYVDCKLGDQHAGLP-------------ALAPIPPAEVDGLEIRTGQKAYLRMQGFVESMKIILGGSMARVGALS---ECPFQGDESIHS-------AVTNALHSILGEQTKALVTQLTLFNQILVELRDDIRDQVKEMSLIRNTIMECQVCGFHEQ------RSHCSPNPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCINTMPGFHCEACPRGYKGTQVSGVGIDYARAS--KQVCNDIDECNDGNNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLPAR-TCHSPAHSPCHIHAHCLFERNGAVSCQCNVGWAGNGNVCGTDTDIDGYPDQALPCMDNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPKVPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECDGDDDNDGIPDYVPP---GPDNCRLVPNPNQKDSDGNGVGDVCEDDFDNDAVVDPLDVCPESAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYWQATPFRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGHTPDQVRLLWTDPRNVGWRDKTSYRWQLLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCNDTVP----EDFEPFRRQLLQGRV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JHW2-1", "uniprot_id": "TSP3A_DANRE", "id": "Q8JHW2-1", "name": "Thrombospondin-3a", "aln": "--------------------------------------------------------------------MEQMFVHIWVSLVVLMSVWSAQSDKKQDVPVIDVLGLEDVKQTVAAVEKLSLALKTLSDVYVMSTFRLPPKLGG----------VLLGLYNKQDN-------KKYLEVAIMSKINKVLVRYVREDGKLHTVNMQSP-NVADGRPQSLILRVGGLRREYLSLELYVNCRLADSAQRLP-------------PLVDLP-RDAELVEIRNGHKAYARMQGSMDTLKLALGGTVAQAGALT---DCPFQGDASSYN-------IVNGEVNSILGDHTKALIGQLIIFNQILGELREDIREQVKEMSLVRNAILECQMCGFHEP------RSRCQPNPCFKGVSCMETFEYPGYRCGPCPDGMTGNGTHCQDIDECSEAQPCYTPGACVNTARGFTCESCPPGMWGPPLSGVGVEYAKSH--RQECSDIDECVDLAN-ACTPNSVCINIIGSFRCGQCKTGYVGNQTAGCFPRK-SCSSLSFNPCDANAHCVMQRNGDVSCACNVGWAGNGHTCGKDTDIDGYPDRSLPCMDNHKHCRQDNCVYTPNSGQEDADNDGIGDQCDEDADGDGIKNVEDNCRLVSNKDQQNSDTDSFGDACDNCPTVPNIDQKDTDSNGEGDACDDDIDGDGIQNVLDNCPKVPNPMQTDRDRDGVGDACDSCPEISNPMQTDVDNDLVGDVCDTNQDTDGDGHQDTRDNCPDIPNSSQLDSDNDGIGDDCDEDDDNDGIPDNHAINGIGPDNCRLISNPNQKDSDSNGVGDVCENDFDNDSVMDLVDVCPESAEVTLTDFRAYQTVILDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDCAGSIFGYQDSSSFYVVMWKQTEQTYWQSIPFRAMAEPGLQLKAVKSRTGPGEFLRNALWHAGDTDGEVKLLWKDPRNVGWLDKTSYRWQLSHRPQVGYIRVKLYEGSEMVADSDVVIDTSMRGGRLGVFCFSQENIIWSNLRYRCNDTVP----EDFSSHRKQVLMHIKV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VM97-1", "uniprot_id": "Q9VM97_DROME", "id": "Q9VM97-1", "name": "", "aln": "---------MNWTRVLLIGLTALALTFVDVASLSLDPVASAELEQFIRKGDVVISTRHIRPRRKLHISIEALFMIDFPMLKHKMSFFLDR---KQQRVTLDISANGATESRNFEIPNINETSTIRSLALQFSKNRITLHVDCKASTHHDIDMNLAKLYTQMDDPVIKLFRERKYPLHFDGDMEHSLQRANCQKGNHRRGNRRMLRNKITEREKNKKRDVRGWYEPTIAREGVVDHRHQEVPTDVERGDIPVLNGDCEDALARSLSDLLALVKLLREDVAHQRQE--IAYLRMLLENCAGCKNPLTTDNQLRIEPDCRSANPCYPGVECLDSAAGPRCGHCPLGFIGDGKSCKPGVTCAHHMCYPGVQCHDTVNGAQCDSCPAGYEGDGRTCSLRNPCLDTPCPSGAQCLQVGYPPYFHCISCPMGHEVNGTSCRDMNECLLYDPCDELATCTNLSPGFQCSPCPVGFDGTHAHGYFADYYSVDYRRQTCLDVDECR-TGFFRCPEHSTCINEIGSYRC-QCHEGYVTNGTYSCLDRSSVFMCPDGTVCDRNAVCLRMDNIRHKCHCNVGWAGNGLICGRDTDVDGWPDQAIGCPELR--CQRDNCPKLPNSGQEDADLDGHGDGCDDDADGDNVQNSQDNCWLAYNTEQLDSDGDKVGDVCDNCVLKYNPRQLDTDEDGLGDECDGDIDNDSIPNALDNCPLLPNPSQSDVDNDGVGDACDNCPNLPNPDQKDRDMDFVGDACHRDIDGDDDGVPNSLDNCPMVSNSDQLDTDGDGTGDECDDDMDGDGIPN-------YKDNCPLAKNPKQDDFNRNGKGDSCEDDEDVDGVPNGMDNCPNNSMIHHTDFRTLQTIPLDPKGLSQADPNWVVHANGTEIVQTLNSDPGLAVGKDAFGGVDFDGTFYINDDTDDDYAGFVFSYQSSYKYYVVQWKKGTQTYWEPRPFTASAAPGIQIKLVNSTEGPGPMMRNSLWHEGNTDGEARLLWKDPKNIAWKERTSYRWSLVHRPAIGLIRLQMHEGNRLIFDSGNVFDSTLKGGRLGVFCFSQRMIIWSNLQYKCNNRVKPLIYNDLSDYLKTKVELQD-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : *: .:*: .. :: : . :*. *:. : . * **.: *: : . ..::: * * :.*: : * : . * :. : * . . . *: : : : .*. ::: . *: * : : ::: * . . ..*: : :: * . : . . *. . .:: : : : :. *: . :..: :. .*:. *. * .** *..*::. * ::* .** * *** * *::** :** .:* * ** *..** * *. * :* :* * *:*** * :* * * :**::* *: *:: * : .* . . *. :* *: * .* ********* ** ***:**:**::: * : . *::*** ********* ** ** **:*****.::* :*** * *.:* :** *..**.**** * * *** :* ** **.*:*.*.* * ***** :*** *:* *.*****:**.**::.** *.* * *:***.*. : * *.** :: **** :.**.***:*.** **:** * *.**:*: *** * **:*.* : ** ** **:* * *.* : :* **:.: : ****: **: ***:* :* ****** :* *****:********* **.****:***::* **** ** :*.**.* :*** **: ****:. ** * * **:*:* *.* *** :**:*** *.* .:.:***.**:*:.* ::***** * *** :* **::::** .:: **. ::*::::***********. ******:*:**: * :*:. . : : ", "identical_positions": 355, "similar_positions": 244, "identity": "32.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020708-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49744-1", "uniprot_id": "TSP4_RAT", "id": "P49744-1", "name": "Thrombospondin-4", "aln": "MTMITPSSKLTLTKGNKSWSSTRCGAFLLLHLVLQPWQRAGAQATPQVFDLLPSSSQRLNPAALQP-VLTDPTLHELYVIS--------TFKLQSKSSATIFGLYSS-SDNSKYFEFTVMGRLNKAILRYLKDDGKIHLVVFNNLQLADGRRHRILLRLSNLQRGAGS-------------VELYLDCVQVDSVNNLPRAFSGLTQNPQAIELRTFQRKPQDFLEELKLVVRGSLFQVASLQDCFLQQSEPLA----ATGTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGP-------------LSFQSPTPNTLVPIAPPAPP---------------TRPTRRCDSSPCFRGVRCTDTRDGFQCGPCPDGYTG------------------------------------------NGITCSDVDECK-YHPCYPGVRCTNLAPGFRCDACPVGFTGPMVQGVGINFAKTN--KQVCTDVDECR---NGACVLNSICINTLGSYRCGPCKPGYTGDQTRGCRT-ERSCRNPEQNPCSVHAQCIEERQGDVTCVCGVGWAGRAGYVCGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNVDQRNTDKDIFGDACDNCRGVLNNDQKDTDGDGKGDACDDDMDGDGIKNILDNCPRVPNRDQQDRDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGMPDLFPPGPDNCRLVPNPAQEDSNNDGVGDICEADFDQDKVIDRIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP----EDFQEFQIQT-FDRLDN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1T2-1", "uniprot_id": "TSP4_MOUSE", "id": "Q9Z1T2-1", "name": "Thrombospondin-4", "aln": "--MPAPR--------------AAAAAFLLLHLVLQPWQRTSAQATPQVFDLLPSSSQRLNPSALQP-VLTDPTLHEVYLIS--------TFKLQSKSSATIFGLYSS-SDNSKYFEFTVMGRLNKAILRYLKNDGKIHLVVFNNLQLADGRRHRVLLRLSNLQRGDGS-------------VELYLDCAQADSVRNLPRAFSGLTQNPESIELRTFQRKPQDFLEELKLVVRGSLFQVASLQDCFLQQSEPLA----ATSTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGP-------------LSFQSPTPNTLVPIAPPAPP---------------TRPTRHCDSSPCFRGVRCTDTRDGFQCGPCPDGYTG------------------------------------------NGITCSDVDECK-YHPCYPGVRCVNLAPGFRCDACPVGFTGPMVQGVGINFAKTN--KQVCTDVDECQ---NGACVLNSICINTLGSYRCGPCKPGYTGDQTRGCKT-ERSCRNPEQNPCSVHAQCIEERQGDVTCVCGVGWAG-DGYVCGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNIDQRNSDKDIFGDACDNCRMVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPRVPNRDQQDRDGDDVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSSQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNNDGVGDICEADFDQDQVIDHIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP----EDFQEFQTQS-FDRLDN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35443-1", "uniprot_id": "TSP4_HUMAN", "id": "P35443-1", "name": "Thrombospondin-4", "aln": "--MLAPR----------------GAAVLLLHLVLQRWLAAGAQATPQVFDLLPSSSQRLNPGALLP-VLTDPALNDLYVIS--------TFKLQTKSSATIFGLYSS-TDNSKYFEFTVMGRLNKAILRYLKNDGKVHLVVFNNLQLADGRRHRILLRLSNLQRGAGS-------------LELYLDCIQVDSVHNLPRAFAGPSQKPETIELRTFQRKPQDFLEELKLVVRGSLFQVASLQDCFLQQSEPLA----ATGTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGP-------------LKFQSPTPSTVVPPAPPAPP---------------TRPPRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTG------------------------------------------NGITCIDVDECK-YHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSN--KQVCTDIDECR---NGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKA-ERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAG-DGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICESDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP----EDFQEFQTQN-FDRFDN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JGW0-1", "uniprot_id": "TSP4B_DANRE", "id": "Q8JGW0-1", "name": "Thrombospondin-4-B", "aln": "----------------------MAGTMHLLTAVSLILMLSSANAESTVYNLLTSP--DCLPDLLHG-GLAEQGVTELYILT--------TFRIQPGTGNTIFSLYNP-RDNSKYFEFSVFGKANKAILRYLRRDGRMSAVTFNKLNLADGEKHRLLFHLKGLEVGHPGGFPHSQGALPVPGVELHLDCRLVETLRDLPAVFNGLN-NHQAVELKTMQGKAQEGLEELKLAYGDSVENVASLQDCHTQ-SDSVQ----ALGLN--TKQLTTQMLELTKVINELKDVLIQQVKETSFLRNTISECQACG----------------------------LSGAEV---------------VKP--KCAPGVCFRDDMCIETAEGVECGPCPDGYTG------------------------------------------DGYSCDDVDECQ-FNPCFPGVRCVNMAPGFRCEACPLGFTGKPLEGVGVAYAQTH--KQVCDDIDECKGPDNGGCTANSICVNSVGSYQCGRCKTGFTGDQIRGCKP-EKSCGNRLQNPCDPNAQCTEERDGTITCQCGIGWAG-NGYLCGKDTDIDGYPDERLRCRDPTCRKDNCVTVPNSGQEDADGDGKGDACDPDADGDGILNEQDNCWLTPNINQQNSDKDSHGDACDNCVRVDNPDQRDTDSDGLGDACDDDMDGDGLKNFLDNCQRVKNRDQLDRDGDGVGDACDSCPDIPNPNQSDIDNDLVGDSCDTNQDSDGDGHQDSKDNCPMVINSSQLDTDKDGIGDECDDDDDNDGIPDSLPPGPDNCRLVPNPEQIDDNNDGVGDICESDFDQDKVIDRIDNCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFSGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWYLQHRPQVGYIRVRFYEGTELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP----EDFQEFSTQHGMDPL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VM97-1", "uniprot_id": "Q9VM97_DROME", "id": "Q9VM97-1", "name": "", "aln": "--MNWTR------------VLLIGLTALALTFVDVASLSLDPVASAELEQFIRKGDVVISTRHIRPRRKLHISIEALFMIDFPMLKHKMSFFLDRKQQRVTLDISANGATESRNFEIPNIN--ETSTIRSLALQFSKNRITLH-VDCKASTHHDIDMNLAKLYTQMDDPVIKLFRE---RKYPLHFDGDMEHSLQRANCQKGNHRRGNRRMLRNKITEREKNKKRDVRGWYEPTIAREGVVDHRHQEVPTDVERGDIPVLNGDCEDALARSLSDLLALVKLLREDVAHQRQEIAYLRMLLENCAGCKNPLTTDNQLRIEPDCRSANPCYPGVECLDSAAGPRCGHCPLGFIGDGKSCKPGVTCAHHMCYPGVQCHDTVNGAQCDSCPAGYEGDGRTCSLRNPCLDTPCPSGAQCLQVGYPPYFHCISCPMGHEVNGTSCRDMNECLLYDPCDELATCTNLSPGFQCSPCPVGFDGTHAHGYFADYYSVDYRRQTCLDVDECRTG-FFRCPEHSTCINEIGSYRC-QCHEGYVTNGTYSCLDRSSVFMCPDGTVCDRNAVCLRMDNIRHKCHCNVGWAG-NGLICGRDTDVDGWPDQAIGCPELRCQRDNCPKLPNSGQEDADLDGHGDGCDDDADGDNVQNSQDNCWLAYNTEQLDSDGDKVGDVCDNCVLKYNPRQLDTDEDGLGDECDGDIDNDSIPNALDNCPLLPNPSQSDVDNDGVGDACDNCPNLPNPDQKDRDMDFVGDACHRDIDGDDDGVPNSLDNCPMVSNSDQLDTDGDGTGDECDDDMDGDGIPNYK----DNCPLAKNPKQDDFNRNGKGDSCEDDEDVDGVPNGMDNCPNNSMIHHTDFRTLQTIPLDPKGLSQADPNWVVHANGTEIVQTLNSDPGLAVGKDAFGGVDFDGTFYINDDTDDDYAGFVFSYQSSYKYYVVQWKKGTQTYWEPRPFTASAAPGIQIKLVNSTEGPGPMMRNSLWHEGNTDGEARLLWKDPKNIAWKERTSYRWSLVHRPAIGLIRLQMHEGNRLIFDSGNVFDSTLKGGRLGVFCFSQRMIIWSNLQYKCNNRVKPLIYNDLSDYLKTK-VELQD-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * .. * . : ::: . . : . : :::: :* :: . :.: :*: **:. :. :.: :* * : :.:: :: . :* : :.* * . *::* .::. . . : ..: : :: .::: :: . . ::. . : . : . . : .: :* :: ::: : :* :* ::** : :* .* . * :* * *: . * :: :* :*..** ** * :* :* *::** :.** . * *::***:*..**:** * .* : . . :*.* *:***: * :* *:* :***:* *: *:. : .* . . *. :* * . : .* *.:**** * :**:*.*:*.:**: : * *::*** :********* ** **.** *****.: *.**** * * :* ::* * **.**** * * *** ** ** **.*:*.*.: * **** . * .* * *.*.******.**::.**:*.* * *:***:*. : *.*.** :* **** * ** ***** ** ******* *.**:*: *** *. ** * * * :* ** ** * * * * : :* **:*: : ****: **: ***:* :* ****** :* *****:********* **.****:***::* ********:*.**.* .:*** **: ****:. ** * * ****:* *:*. *** :****** *:*..:.******.:*:.**::.**** * *** :* **::::**..*: *** .:*:*::***********. ******:*:**: : :*:.:: .: ", "identical_positions": 355, "similar_positions": 255, "identity": "32.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020711-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P03966-1", "uniprot_id": "MYCN_MOUSE", "id": "P03966-1", "name": "N-myc proto-oncogene protein", "aln": "MPSCTASTMPGMICKNPDLEFDSLQPCFYPD--EDDFYFGGPDSTPPGEDIWKKFELLPTPPLSPSRAFPEHSPEPSNWATEMLLPEADLWGNPA-EEDAFGLGGLGGLTPNPVILQDCMWSGFSAREKLERAVNEKLQHGHGPPGVSSACSAPGVGASSPGGRALGGSSSASHTGATLPTDLSHPAAECVDPAVVFPFPVNKRESASVPAAPTSAPATSAAVTS---VSVPATAPVAAPARAGGRPASSGEAKALSTSGEDTLSDSDDEDDEEEDEEEEIDVVTVEKRRSSSNNKAVTTFTITVRPKTSALGLGRAQPGELILKRCVPIHQQHNYAAPSPYVESEDAPPQKKIKSEASPRPLKSVVPAKAKSLSPR-NSDSEDSERRRNHNILERQRRNDLRSSFLTLRDHVPELVKNEKAAKVVILKKATEYVHALQANEHQLLLEKEKLQARQQQLLKKIEHARTC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63379-1", "uniprot_id": "MYCN_RAT", "id": "Q63379-1", "name": "N-myc proto-oncogene protein", "aln": "MPSCTASTMPGMICKNPDLEFDSLQPCFYPD--EDDFYFGGPDSTPPGEDIWKKFELLPTPPLSPSRAFPEHSPEPSNWATEMLLPEADLWGNPA-EEDAFGLGGLGGLTPNPVILQDCMWSGFSAREKLERAVNEKLQHGHGPPGASSSCPAPGVGASSSGGRALGGSASAGRTGATLPTDLSHPAAECVDPAVVFPFPVNKRESASVPAAPTSAPATSAVVTS---VSVPAVAPVAAPARGSGRPANSGEHKALSTSGEDTLSDSDDEDDEEEDEEEEIDVVTVEKRRSSSNNKAVTTFTITVRPKTSALGLGRAQPGELILKRCVPIHQQHNYAAPSPYVESEDAPPQKKIKSEASPRPLKSVVPPKAKSLSPR-NSDSEDSERRRNHNILERQRRNDLRSSFLTLRDHVPELVKNEKAAKVVILKKATEYVHALQANEHQLLLEKEKLQARQQQLLKKIEHARTC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04198-1", "uniprot_id": "MYCN_HUMAN", "id": "P04198-1", "name": "N-myc proto-oncogene protein", "aln": "MPSCSTSTMPGMICKNPDLEFDSLQPCFYPD--EDDFYFGGPDSTPPGEDIWKKFELLPTPPLSPSRGFAEHSSEPPSWVTEMLL-ENELWGSPA-EEDAFGLGGLGGLTPNPVILQDCMWSGFSAREKLERAVSEKLQHGRGPPTAGSTAQSPGAGAASPAGRGHGGAAGAGRAGAALPAELAHPAAECVDPAVVFPFPVNKREPAPVPAAPASAPAAGPAVASGAGIAAPAGAPGVAPPRPGGRQTSGGDHKALSTSGEDTLSDSDDEDDEEEDEEEEIDVVTVEKRRSSSNTKAVTTFTITVRPKNAALGPGRAQSSELILKRCLPIHQQHNYAAPSPYVESEDAPPQKKIKSEASPRPLKSVIPPKAKSLSPR-NSDSEDSERRRNHNILERQRRNDLRSSFLTLRDHVPELVKNEKAAKVVILKKATEYVHSLQAEEHQLLLEKEKLQARQQQLLKKIEHARTC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23999-1", "uniprot_id": "MYCS_RAT", "id": "P23999-1", "name": "Protein S-Myc", "aln": "MLSCTTSTMPGMICKNSDLEFDSLKPCFYPE--DDDIYFGGRNSTPPGEDIWKKFELLPTPRLSPGRALAEDSLEPANWATEMLLPEADLWSNPAEEEDIFGLKGLSGSSSNPVVLQDCMWSGFSSREKPETVVSEKLPGGCGSLAVGAGTLVPGAAAATSAGHARSGTAGVGRRKAAWLTELSHLDSECVDSAVIF--PANKRESMPVATIPASAGAA----------------------------ISLGDHQGLSSSLEDFLSNS----GYVEEGGEEIYVVMLGETQFS---KTVTKLPTAAHSENAALTPECAQSGELILKRSDLIQEQHNYAAP-PLPYAEDARPLKKPRSQDPLGPLKCVLRPKAPRLRSRSNSDLEDIERRRNHNRMERQRRDIMRSSFLNLRDLVPELVHNEKAAKVVILKKATEYIHTLQTDESKLLVEREKLYERKQQLLEKIKQSAVC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9PSJ0-1", "uniprot_id": "MYCN_DANRE", "id": "Q9PSJ0-1", "name": "N-myc protein", "aln": "------------------------------------------------EDIWKKFELLPTPPLSPSR--------------------AALPGDPG------ELGAVAG---------DCSLMGFGLTDPLDWASELLLLPGDDIWG-----------------------------------------------------------------------------------------------------ASDGD---LFGSVLDTTDNS------------------------------------------------------IIIQDC----MWSGFSA-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15063-1", "uniprot_id": "MYCB_RAT", "id": "P15063-1", "name": "Protein B-Myc", "aln": "-----MPLHVSLANGNRDLDYDSVQPYFMCDDEEEDVHQQPPQPPAPSEDIWKKFELLPTPRPSPGHP--------------------GLYSPPC----------------------EAVAASFSPRDHDGDSFSTADLP--ELPG------------------------------------------------------------------------------------------------------DAVKQSFVCDPDDETFVKN------------------------------------------------------IILQDC----MWNGFSASAKLVSKLDPYQAVR-KEGASVSPAADVEPATPPDCTCNT-------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ************* **.: * . * :. .*. : . . . : . : .. :*:: . .::* ", "identical_positions": 20, "similar_positions": 23, "identity": "4.26%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020712-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B4F7E7-1", "uniprot_id": "PALS1_RAT", "id": "B4F7E7-1", "name": "Protein PALS1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTTSYMNGHVTEESDSGIKNLGLASPEEHP-----------------------------------------KHREMAVDCPG----------------DLGTR----------------------------------------------------------------------------------------------LMPVRRS-----------------------------AQLERIRQQQEDMRRRREEE---GKKQELDLNSSMRLKKLAQIPPKTGIDNPIFDTEEG---------------IVLESPHYAVKILEVEDLFSSLKHIQHTLVDS---QSQEDISLLLQLVQNRDFQNAFKIHNAVTVHMNKASPPFPLIANVQDLVQEVQTVLKPVHQKEGQELTALLNAPHIQALLLAHDKVAEQ------------------------------EMQLEPITDER-VYESIGHYG-----------------------------------------GETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS-----------------QQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDK----------EPEKSGKLWCAKKNKKKRKKV-------LYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRNRRDHEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRAQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWLR------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLB2-1", "uniprot_id": "PALS1_MOUSE", "id": "Q9JLB2-1", "name": "Protein PALS1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTTSYMNGHVTEESDSGIKNLDLASPEEYP-----------------------------------------KHREMAVDCPG----------------DLGTR----------------------------------------------------------------------------------------------MMPVRRS-----------------------------AQLERIRQQQEDMRRRREEE---GKKQELDLNSSMRLKKLAQIPPKTGIDNPIFDTEEG---------------IVLESPHYAVNILDVEDLFSSLKHIQHTLVDS---QSQEDISLLLQLVQNRDFQNAFKIHNAVTVHMSKASPPFPLIANVQDLVQEVQTVLKPVHQKEGQELTALLNAPHIQALLLAHDKVAEQ------------------------------EMQLEPITDER-VYESIGHYG-----------------------------------------GETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS-----------------QQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDK----------EPEKSGKLWCAKKNKKKRKKV-------LYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRNRRDHEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWLR------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N3R9-1", "uniprot_id": "PALS1_HUMAN", "id": "Q8N3R9-1", "name": "Protein PALS1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTTSHMNGHVTEESDSEVKNVDLASPEEHQ-----------------------------------------KHREMAVDCPG----------------DLGTR----------------------------------------------------------------------------------------------MMPIRRS-----------------------------AQLERIRQQQEDMRRRREEE---GKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEG---------------IVLESPHYAVKILEIEDLFSSLKHIQHTLVDS---QSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQ------------------------------EMQLEPITDER-VYESIGQYG-----------------------------------------GETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS-----------------QQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDK----------EPEKSGKLWCAKKNKKKRKKV-------LYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWLR------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JHF4-1", "uniprot_id": "PAL1A_DANRE", "id": "Q8JHF4-1", "name": "Protein PALS1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTTSHMNGYVTESDGGGGTDI---VEEGVQ-----------------------------------------RHREMAVDCPS----------------ELGAR----------------------------------------------------------------------------------------------TLPVRRS-----------------------------AQLEKIRQQQEDRRRREEEG---RSRQELDLNSSMRLKKLSQNP-KVGIDNPTFEQMEGP----------GGSAGGLQSLIAPPALLELEDLLMSLKQVQHSLNDS---QSQEDVELVLQLVQKPDFQKAFSIHNSVAHYMNRPSPPYPLTDHAQTLAQEVEVMVQNSSHKEGLELSSLLSTSHMQALMMAHDSVAEQ------------------------------EMQLEPLVPSVNASETLTQWG-----------------------------------------GETVKIVRIEKAKDIPLGATVRNDMDSVVISRIVKGGAAERSGLLHEGDEILEINGVEIRGKDVNEVFDILADMHGVLSFVLIPS-----------------AQIKSPPIKETVVHVKAHFDYDPSDDPYVPCRELGLCFQKGDILHIISQDDPNWWQAYRDGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDK----------EPEKTGKLWCAKKTKKKRKKM-------QYNANKNDDFDNEEILTYEEMALYHQPANRKRPIALIGPPNCGQNELRQRLLSTEPDRFAGPVPHTTRSRRDAEANGRDYHFVSRQAFEMDSAAGKFIESGEFEKNFYGTSTDSVRQVINTGKICLLCVHTQSLKVLRSSDLKPYIIFIAPPSQERLRALLAKDNKNPKPEELRDIIEKAREMEQNYGHLFDAAIVNTDLDKSYQELLRLINKLDTEPQWVPSSWLR------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E2QD98-1", "uniprot_id": "E2QD98_DROME", "id": "E2QD98-1", "name": "Protein PALS1", "aln": "MQANSSRSNLSAQSSGTPSASTISSSQGKQQVVELSGYVIILVENVEGKIKLYGSPPDRDNLEVGDEILEVNGLTLENISRTEVIRHIHDCIKSCTICLRVRKKNDSRLAWDIGNSVQDAFVIAVEEHARERLQRLAALNRVTPVDITQLSKKLQQTKSGTATSQRQDLSFLNESTPIYVTSFTSNQITCSSSTMTTATAGGPISAPSLATATTTVPTASSHTTTVVAQIEHGASALVSAAVAAATAADRNANSTTSAALKQTANCIGNSTSSLGTTSTTSSQSTSSATGHIYQTSQAQQQQLQQLQQQLAAAAAAGKPLQAKSLLASSLQHLAEEVDNEDLDDDDDVDGANYCGITYISYNNKHAQLPTTTLPATTALPAAAASLATTAAIYQQRQQQQHQQQQQQQQQPVHHHNHPPTASQLNRATAPAPLQLGGPVNPSFVDAQTSTSPLMAQQLHSQHADVDAAPPSSSSSSAVVVVERHVHGTTTPKTEYSTAISSGQLQQAFAELQLHSSNNNATQQQQQHLLLSNNNNSNNSMAAAQTTASLMKNCDLLISNNLYPPRRELLEDVIVHQASDVHSYSTSASAAAIASSSNRSQQQQQQQQQHQLLSAAYELQQQQQLQLQQQQQQQNSPTSSISIGRTELLLGDQSLRQDPRGNRRRSGSSIVVLDGDDLKPCLPDDYISGQHHLNHQQQLQLQQQLQQQHPLQQQHYRTHSGDIREIDQEMLTMLSVNQDNGPHREMAVDCPDTFIARNKTPPRYPPPRPPQKHKKSTNTTTTTTITALTNNDHANKMLIVAYHSSHQHEQLQQQHPSKTSTTTTTIALDVATQNLYNQKQQNKLEQIENYENCLQSERNEQHEQQFEQQKQHQATTAMAATQVAQQQTPSHKLQATLSSDPNGNSNSNNNSHIVGISSSSSSNNSSITDDFLCVVDGLYQGRKDTASPSSSAFDEVMSKHTLDSFGSIAYRHLHQQHQATSNGNSSSNTSNTNSNTNSNTNSNSNTNGNTSNNTAVSTKTATVTKTGVSSSNSNSNSLNSSNSSMHTSSSSSGHSSNIASATSSSSATSSSTVPDDLSLAPPGYEVSQQQQQQHLVATPVTMLLPPMAKHRELPVDVPDSFIEMVKTTPRYPPPAHLSSRGSLLSNGSASTAHTTLSSMGVAPSPVTATAAAAASASAACATTAVAAAAVSGVADGDARRVADELNGNAKPVPPPRDHLRVEKDGRLVNCSPAPQLPDRRAPGNASSGSSGATTHPLQHQQIAQIVEPTLEQLDSIKKYQEQLRRRREEEERIAQQNEFLRNSLRGSRKLKALQDTATPGKAVAQQQQQATLATQVVGVENEAYLPDEDQPQAEQIDGYGELIAALTRLQNQLSKSGLSTLAGRVSAAHSVLASASVAHVLAARTAVLQRR-RSRVSGPLHHSSLGLQKDIVELLTQSNTAAAIELGNLLTSHEMEGLLLAHDRIANHTDGTPSPTPTPTPAIGAATGSTLSSPVAGPKRNLGMVVPPPVVPPPLAQRGAMPLPRGESPPPVPMPPLATMPMSMPVNLPMSACFGTLNDQNDNIRIIQIEKS-TEPLGATVRNEGEAVVIGRIVRGGAAEKSGLLHEGDEILEVNGQELRGKTVNEVCALLGAMQGTLTFLIVPAGSPPSVGVMGGTTGSQLAGLGGAHRDTAVLHVRAHFDYDPEDDLYIPCRELGISFQKGDVLHVISREDPNWWQAYREGEED-QTLAGLIPSQSFQHQRETMKLAIAEEAGLARSRGKDGSGSKGATLLCARKGRKKKKKASSEAGYPLYATTAPDETDPEEILTYEEVALYYPRATHKRPIVLIGPPNIGRHELRQRLMAD-SERFSAAVPHTSRARREGEVPGVDYHFITRQAFEADILARRFVEHGEYEKAYYGTSLEAIRTVVASGKICVLNLHPQSLKLLRASDLKPYVVLVAPPSLDKLRQKKLRNGEPFKEEELKDIIATARDMEARWGHLFDMIIINNDTERAYHQLLAEINSLEREPQWVPAQWVHNNRDES", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:* . :.:..... .:: . :***:.** *. .*.:* :* **: **: *:: **: ***.** .::*: ** :** .. .:. : : :. . : :*: :*.::*: * .* :. .:: . .. :.: :.:: :. . ** * ::: :: . ** **.: .::.*::*** :*:: : :* :. . .: : * .:.::*::***: ********: ::*:*.***:*****:*********:**:** *:*** **** :*. *:*.*:*:::*: : . . :*:**:*******.** *:******:.*****:**:**::*********:*:** *.****:*.:***:***:** :* *: . .* ..* **:* :**:** * :. *: * ********::**: *.:**** **** * *::******: :**:..****:* **: *. * ****::***** * * :*:* **:** **** :::* *: :****:* ::.**** ** ******::::**** ::** ::.: * ***::** .:*:** . ** ** *:*.* :::*::** **.*: ******: *:: ", "identical_positions": 276, "similar_positions": 215, "identity": "13.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020717-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q71PD7-1", "uniprot_id": "H2AV_DANRE", "id": "Q71PD7-1", "name": "Histone H2A.V", "aln": "MAG---GKAGKDSGK--AKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKG------QQKTA-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q71UI9-1", "uniprot_id": "H2AV_HUMAN", "id": "Q71UI9-1", "name": "Histone H2A.V", "aln": "MAG---GKAGKDSGK--AKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKG------QQKTA-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3THW5-1", "uniprot_id": "H2AV_MOUSE", "id": "Q3THW5-1", "name": "Histone H2A.V", "aln": "MAG---GKAGKDSGK--AKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKG------QQKTA-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C0S7-1", "uniprot_id": "H2AZ_RAT", "id": "P0C0S7-1", "name": "Histone H2A.Z", "aln": "MAG---GKAGKDSGK--AKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKG------QQKTV-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08985-1", "uniprot_id": "H2AV_DROME", "id": "P08985-1", "name": "Histone H2A.v", "aln": "MAG---GKAGKDSGK--AKAKAVSRSARAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKEETVQDPQRKGNVILSQAY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12692-1", "uniprot_id": "H2AZ_YEAST", "id": "Q12692-1", "name": "Histone H2A.Z", "aln": "MSGKAHGGKGKSGAKDSGSLRSQSSSARAGLQFPVGRIKRYLKRHATGRTRVGSKAAIYLTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGDDELDSLIRATIASGGVLPHINKALLLKVE-------KKGSKK-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* * **...* .. :: * * ***********:*:** ::*.: ***:.**:* :*:***************:********************:******:****.***:***:*:*: * :* ", "identical_positions": 85, "similar_positions": 28, "identity": "58.22%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020731-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54370-1", "uniprot_id": "OAZ1_RAT", "id": "P54370-1", "name": "Ornithine decarboxylase antizyme 1", "aln": "--------------------------MVKSSLQRILNSHCFAREKEGDKRSATLHASRTMPLLSQHSRGGCSSESSRVALHCCSNLGPGPRWCSDVPHPPLKIPGGRG-NSQRDHSLSASILYSDERLNVTEEP-TSNDKTRVLSIQCTLTEAKQVTWRAVWNGGG--LYIELPAGPLPEGSKDSFAALLEFAEEQLRADHVFICFPKNREDRAALLRTFSFLGFEIVRPGHPLVP----KRPDACFMVYTLEREDPGEED-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54369-1", "uniprot_id": "OAZ1_MOUSE", "id": "P54369-1", "name": "Ornithine decarboxylase antizyme 1", "aln": "--------------------------MVKSSLQRILNSHCFAREKEGDKRSATLHASRTMPLLSQHSRGGCSSESSRVALNCCSNLGPGPRWCSDVPHPPLKIPGGRG-NSQRDHSLSASILYSDERLNVTEEP-TSNDKTRVLSIQSTLTEAKQVTWRAVWSGGG--LYIELPAGPLPEGSKDSFAALLEFAEEQLQADHVFICFPKNREDRAALLRTFSFLGFEIVRPGHPLVP----KRPDACFMVYTLEREDPGEED-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54368-1", "uniprot_id": "OAZ1_HUMAN", "id": "P54368-1", "name": "Ornithine decarboxylase antizyme 1", "aln": "--------------------------MVKSSLQRILNSHCFAREKEGDKPSATIHASRTMPLLSLHSRGGSSSESSRVSLHCCSNPGPGPRWCSDAPHPPLKIPGGRG-NSQRDHNLSANLFYSDDRLNVTEEL-TSNDKTRILNVQSRLTDAKRINWRTVLSGGS--LYIEIPGGALPEGSKDSFAVLLEFAEEQLRADHVFICFHKNREDRAALLRTFSFLGFEIVRPGHPLVP----KRPDACFMAYTFERESSGEEEE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9YI98-1", "uniprot_id": "OAZ1_DANRE", "id": "Q9YI98-1", "name": "Ornithine decarboxylase antizyme 1", "aln": "--------------------------MVKSNLQTILNSHCFVREKESNIP--------KMPVIELT-RNKPESESS----HRCSNPCPGPLWCSDVPLPPLKIPGGRG-NDQRDHSLSAKLFYSDAQLLVLEEAPQSNSRVRFLLFERRCSVSKHLVWRGALKGTN--LYIEIPTGVLPEGSKDSFSLLLEFAEEKLQVDHVFICFHKSRDDRASLLRTFSFMGFEIVRPGHPLVP----TRPDAFFMAYRIERDSDGDE--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P54361-1", "uniprot_id": "OAZ_DROME", "id": "P54361-1", "name": "Ornithine decarboxylase antizyme", "aln": "MPSNMNNKLDPVFSSGFVRREFNDSGIADGKLRTISTSSCATTMSSESYRISLGVGPLWWSDVPVHHRTDHDRASLLTGYSRKSSVDSAGGSLYEASSRASSLSSSQSDCSDLESQPDIHSLCSDDDCQEVLRQILQHDQPVQITIKLHVTEDQYTNWNTILNPVNNLLYVALPKDLPPAGSKQTFISLLEFAEEKLEVDGIVMVMPKDQPDRARLIEAFLFMGFEPLSRKAPQAPPAAINDNENYYFLYSIEE--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :....*: * .* * . .. . . : * . * *. .. :.. . .:...:. .: : . . : ** . .:.: : .: : : *. . . **: :* . * ***::* *******:*..* :.: : *.: *** *:.:* *:*** : * .* . : :: * :*. ", "identical_positions": 41, "similar_positions": 73, "identity": "15.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020731-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54368-1", "uniprot_id": "OAZ1_HUMAN", "id": "P54368-1", "name": "Ornithine decarboxylase antizyme 1", "aln": "---MVKSSLQRILNSHCFAREKE----GDKPSATIHASRTMPLLSLHSR---------------------GGSSSESSRVSLHCCSNPGPGPRWCSDAPHPPLKIPGGRGNSQRDHNLSANLFYSDDRLNVTEELTSNDKTRILNVQSRLTDAKRINWRTVLS--GGSLYIEIPGGALPEGSKDSFAVLLEFAEEQLRADHVFICFHKNREDRAALLRTFSFLGFEIVRPGHPLVPKRPDACFMAYTFERESSGEEEE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54369-1", "uniprot_id": "OAZ1_MOUSE", "id": "P54369-1", "name": "Ornithine decarboxylase antizyme 1", "aln": "---MVKSSLQRILNSHCFAREKE----GDKRSATLHASRTMPLLSQHSR---------------------GGCSSESSRVALNCCSNLGPGPRWCSDVPHPPLKIPGGRGNSQRDHSLSASILYSDERLNVTEEPTSNDKTRVLSIQSTLTEAKQVTWRAVWS--GGGLYIELPAGPLPEGSKDSFAALLEFAEEQLQADHVFICFPKNREDRAALLRTFSFLGFEIVRPGHPLVPKRPDACFMVYTLEREDPGEED-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9YI97-1", "uniprot_id": "OAZ2_DANRE", "id": "Q9YI97-1", "name": "Ornithine decarboxylase antizyme 2", "aln": "---MVKSNLQRILNSHCFAREKE----GKKQ----CESSIMEALSSSIT---------------------DRMASP----TVCCSSTTGPGPLWCSDAPHPPLKIPGGRGNGARDHPSTTQTLYSDRKLTVTEEPAGPGRPQILHFQSRPAAARLIQWEAVLR--GDGLFVEIPCEPFPDGSKESFISLLEFAEEHLKVVSVFVCFYKNREDRVKLVRTFSFLGFEMVKPGHALVPARPDVLFMAYNFDRDSSDED--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P54361-1", "uniprot_id": "OAZ_DROME", "id": "P54361-1", "name": "Ornithine decarboxylase antizyme", "aln": "MPSNMNNKLDPVFSSGFVRREFNDSGIADGKLRTISTSSCATTMSSESYRISLGVGPLWWSDVPVHHRTDHDRASLLTGYSRKSSVDSAGGSLYEASSRASSLSSSQSDCSDLESQPDIHSLCSDDDCQEVLRQILQHDQPVQITIKLHVTEDQYTNWNTILNPVNNLLYVALPKDLPPAGSKQTFISLLEFAEEKLEVDGIVMVMPKDQPDRARLIEAFLFMGFEPLSRKAPQAP--PAAINDNENYYFLYSIEE--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::..*: ::.* . ** : .. * :* :* : .. . *. : :. ..*. . . .. ..: . .* * .: .:. : .: : : *.:: .. *:: :* * ***::* *******:*.. :.: : *:: **. *:.:* *:*** : . .* * . . . *: ", "identical_positions": 39, "similar_positions": 75, "identity": "15.12%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020801-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MH9-1", "uniprot_id": "BBS2_RAT", "id": "Q99MH9-1", "name": "BBSome complex member BBS2", "aln": "MLLPVFTLKLRHKISPRMVAIGRYDGTHPCLAAATQAGKVFIHNPHMRSQHFSTSRVFQSPLESDVSLLNINQTVSCLGAGVLNPELGYDTLLVGTQTSLLAYDIYNNSDLFYREVADGANALVLGTLGDIAPPLAIIGGNCALQGFDHEGNDLFWTVTGDNVHSLALCDFDGDGKSELLVGSEDFDIRVFKEDEIVAEMTETEIVTSLCPMYGSRFGYALSNGTVGVYDKTARYWRIKSKNHAMSIHAFDINSDGVCELITGWSNGKVDARSDRTGEVIFKDNFSSAVAGVVEGDYRMDGHVQLICCSVDGEIRGYLPGTAEMKGNLLDTSVEQGLIRELSQKKQNLLLELRNYEENTKAELSSPLNEADGQKGIIPANTKLHTALSVNLGNDAQDAHAELRISTSNDTIIRAVLIFAEGIFAGESHVVHPSTHNLSSSIRVPITPPKDVPVDLHLKTFVGYRSSTQFHVFELIRQLPRFTMYALTSPDAASEPVSFVNFIVVERAQRMVTWLNQNFLLPEDSNIQNAPFHVCFTSLRNGGQLYIKMKPSGEITVNTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEELRKVLLKVDEYHSVHQKLSANMADNSNLIRSLLVRAEDARLMRDMKTMKTRYMELYDLNKDLLNGYKIRCNNHTELLGNLKAVNQAIQRAGRLRVGKPKNQVISACRDAIRSNNINTLFRIMRVGTAPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWF6-1", "uniprot_id": "BBS2_MOUSE", "id": "Q9CWF6-1", "name": "BBSome complex member BBS2", "aln": "MLLPVFTLKLRHKISPRMVAIGRYDGTHPCLAAATQAGKVFIHNPHTRSQHFSASRVFQSPLESDVSLLNINQTVSCLGSGVLNPELGYDTLLVGTQTSLLAYDIYNNSDLFYREVSDGANAIVLGTLGDIAPPLAIIGGNCALQGFDHEGNDLFWTVTGDNVHSLALCDFDGDGKTELLVGSEDFDIRVFKEDEIVAEMTETEIVTSLCPMYGSRFGYALSNGTVGVYDKTARYWRIKSKNHAMSIHAFDINSDGVCELITGWSNGKVDARSDRTGEVIFKDNFSSAVAGVVEGDYRMDGHVQLICCSVDGEIRGYLPGTAEMKGNLLDTSVEQDLIRELSQKKQNLLLELRNYEESTKAELSSPLNEADGQKGIIPANTRLHTALSVNMGNDLQDAHAELGISTSNDTIIRAVLIFAEGIFVGESHVVHPSIHNLSSSLRVPITPPKDVPVDLHLKTFVGYRSSTQFHVFELTRQLPRFTMYALTSPDAASEPVSYVNFSVAERTQRMVTWLNQNFLLPEDSNVQNSPFHVCFTSLRNGGQLYIKMKQSGEITVNTDDIDLAGDIIQSIASFFAIEDLQVEADFPVYFEELRKVLVKVDEYHSVHQKLSADMADNSNLIRSLLVRAEDARLMRDMKTMKSRYMELYDLNKDLLNGYKIRCNNHTELLGNLKAVNQAIQRAGRLRVGKPKNQVISACRDAIRSNNINTLFRIMRVGTAPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXC9-1", "uniprot_id": "BBS2_HUMAN", "id": "Q9BXC9-1", "name": "BBSome complex member BBS2", "aln": "MLLPVFTLKLRHKISPRMVAIGRYDGTHPCLAAATQTGKVFIHNPHTRNQHVSASRVFQSPLESDVSLLSINQAVSCLTAGVLNPELGYDALLVGTQTNLLAYDVYNNSDLFYREVADGANAIVLGTLGDISSPLAIIGGNCALQGFNHEGSDLFWTVTGDNVNSLALCDFDGDGKKELLVGSEDFDIRVFKEDEIVAEMTETEIVTSLCPMYGSRFGYALSNGTVGVYDKTSRYWRIKSKNHAMSIHAFDLNSDGVNELITGWSNGKVDARSDRTGEVIFKDNFSSAIAGVVEGDYRMDGHIQLICCSVDGEIRGYLPGTAEMRGNLMDTSAEQDLIRELSQKKQNLLLELRNYEENAKAELASPLNEADGHRGIIPANTRLHTTLSVSLGNETQTAHTELRISTSNDTIIRAVLIFAEGIFTGESHVVHPSIHNLSSSICIPIVPPKDVPVDLHLKAFVGYRSSTQFHVFESTRQLPRFSMYALTSLDPASEPISYVNFTIAERAQRVVVWLGQNFLLPEDTHIQNAPFQVCFTSLRNGGHLHIKIKLSGEITINTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEELRKVLVKVDEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSRYMELYDLNRDLLNGYKIRCNNHTELLGNLKAVNQAIQRAGRLRVGKPKNQVITACRDAIRSNNINTLFKIMRVGTASS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q98SP7-1", "uniprot_id": "BBS2_DANRE", "id": "Q98SP7-1", "name": "BBSome complex member BBS2", "aln": "MLVPIFTLKLNHKINPRMVAIGKYDGIHPCLTAATQAGKVFIHNPHTRAQRPTAHRLSQSTQDSDISLLNINQSVSCLTAGTLGPKSTGDTLLVGSQTNLLAYDVHDNTDVFYKEVTDGANAIVLGKLGDIQSPLAIIGGNCALQGFDYEGNDLFWTVTGDNVRSLVLCDFTADGKNELLVGSEDFDIRVFKEDELVTEMAENETVTSLCHMHGSRFGYALANGTVGVYDRTARYWRIKSKNHAMSIHAFDLNADGVVELITGWSNGKIDARSDRTGEVIFKDNFSSSVAGVVEGDYRMDGQIQLICTSVEGEVRGYLPASKEMKGNLMDSSIEQDLIRELSQRKQNLMLELRNYEENAKALPG--LSEGESKMGVIPANTQLQTALSVRRASESQKAHIELNISTPNETIIRAVLIFAEGIFEGESHVVHPSAQNLSGCVRVPIIPPKDIPVDLHIKAFVGGKTSTQFHVFEITRQLPRFSMYDLNVDPSAPEPTGKVTFCINDRPQRVVMWLNQNFLLPEGIDSPD----VTFSALRGGGLLRISLQTSGEITLRTDDIDLAGDLVQSLASFLAIEDLQAESDFPVYFKELRATLTEVDEFHSVHQKLTAAMADHSNYIRNMLVQAEDARLMGDWRNMKKRYIELYDLNRDLVNEYKIRSNNHNALLARLKSVNQAIQRAGRLRVGKPKSQVITACRDAIKNNNINALFKIMRAGTTSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*:*****.***.*******:*** ****:****:********* * *: :: *: **. :**:***.***:**** :*.*.*: *:****:**.*****:::*:*:**:**:*****:***.**** .**************::**.***********.**.**** .***.******************:*:**:*.* ***** *:********:********:*:******************:*:*** **********:******************::************::**** **:**:*****.: **:***:*:* **.*******:****:********.:** . *.*.:.: *:*****:*:*:*** ..: * ** ** ***.*:************** ********* :***..: :** ****:*****:*:*** ::******** ******:** *. .*.** . *.* : :*.**:* **.*******. . : * *::**.** * *.:: *****:.*********::**:***:******.*:******:*** .* :***:*******:* ***:** **.:** ******* * :.**.**:******:**:* ****.***. **..**:*****************.***:******:.****:**:***.**:.*", "identical_positions": 507, "similar_positions": 148, "identity": "70.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020802-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62915-1", "uniprot_id": "CSKP_RAT", "id": "Q62915-1", "name": "Peripheral plasma membrane protein CASK", "aln": "MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLG--ESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSEDPTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKIN-TKSSPQIRNPPSDAVQRAKEVLEEISCYPENN------DAKELKRILTQPHFMALLQTHHVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERDSPSTSRQSPANGHSSTNNSVS------------IYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHN-----ADLVTYEEVVKLPA----FKRKTLVLLGAHGVGRRHIKNTLITKHPERFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFPPFVVFIAAPTIT--PGLNE---------DESLQRLQKESDVLQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70589-1", "uniprot_id": "CSKP_MOUSE", "id": "O70589-1", "name": "Peripheral plasma membrane protein CASK", "aln": "MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLG--ESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSEDPTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKIN-TKSSPQIRNPPSDAVQRAKEVLEEISCYPENN------DAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERDSPSTSRQSPANGHSSTNNSVSDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNAVFDQLDLVTYEEVVKLPA----FKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTIT--PGLNE---------DESLQRLQKESDVLQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14936-1", "uniprot_id": "CSKP_HUMAN", "id": "O14936-1", "name": "Peripheral plasma membrane protein CASK", "aln": "MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLG--ESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSEDPTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKIN-TKSSPQIRNPPSDAVQRAKEVLEEISCYPENN------DAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERDSPSTSRQSPANGHSSTNNSVSDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNAVFDQLDLVTYEEVVKLPA----FKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTIT--PGLNE---------DESLQRLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z057-1", "uniprot_id": "A0A8M6Z057_DANRE", "id": "A0A8M6Z057-1", "name": "Peripheral plasma membrane protein CASK", "aln": "MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLG--ESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEAIIKGKYKMNPRQWGHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSEDPTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDHHLHTLLDLYDKIN-TKSSPQIRNPSSDAVQRAKEVLEEISCYPENT------DAKELRRILTQPHFMALLQTHDVVAHEVYSDDAMRVTPPPTSPYLNGDSPESTNGDMDIENVTRVRLVQFQKNTDEPMGITLKMNDLNHCIVARIMHGGMIHRQGTLHIGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQQSSCEKESPSTSRQSPANGHSSINSSILDLPSTIQPKGRQIYVRAQFEYDPVKDDLIPCKEAGIRFRVGDIIQIINKDDHNWWQGKLENTKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNAVFDQLDLVTYEEVVKLPA----FKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYFFVSHDQMMQDISNNDYLEYGSHEDAMYGTRLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPYVVFIAAPTIT--PGMNELPRWCRKLPDESLQRLQKESEILQKTYAHYFDQTIINNEIDETIRLLEEAIDMVCSTAQWVPVSWVY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24210-3", "uniprot_id": "CSKP_DROME", "id": "Q24210-3", "name": "Peripheral plasma membrane protein CASK", "aln": "MTEDEILFDDVYELCEVIGKGPFSIVRRCIHRESNQQFAVKIVDVAKFTASPGLSTADLKREATICHMLKHPHIVELLETYSSEGMLYMVFEFMEGSDLCFEVVRRAVAGFVYSEAVACHYMRQILEALRYCHENDILHRDVRPACALLATVDNSAPVKLGGFGSAIQLPGTRETIETHGRVGCPHYMAPEVVTRRLYGKGCDVWGAGVMLHVLLSGRLPFLGSGVRLQQSVARGRLSFEAPEWKSISANAKDLVMKMLAANPHHRLSITEVLDHPWIRDRDK-LQRTHLADTVEELKRYNARRKLKGAVQAIAGGTNMDPLYAT-DADMPITGATDEWADEEAGIEAVQRILDCLDDIYSLQDAH-VDADVLRDMLRDNRLHQFLQLFDRIAATVVTSNGRAPAAEAVGRCRDVLEQLSSTSGGNSLGGKYAKEELMRLLAAPHMQALLHSHDVVARDVYGEEALRVTPPPMVPYLNGDELDNVEG-GELQHVTRVRLVQFQKNTDEPMGITLKMTEDGRCIVARIMHGGMIHRQATLHVGDEIREINGQPVQHQSVGQLQRMLREARGSVTFKIVPSYRSAPPPCE-----------------------------------IFVRAQFDYNPLDDELIPCAQAGISFQVGDILQIISKDDHHWWQARLDTVG-GSAGLIPSPELQEWRIACQTVDKTKQEQ-VNCSIFGRKKKQCRDKYLAKHNAIFDTLDVVTYEEVVKVPVGDPNFQRKTLVLLGAHGVGRRHIKNTLISKYPDKYAYPIPHTTRPAKPEEENGRSYYFVSHDEMMADIGANEYLEYGTHEDAMYGTKLDTIRRIHTEGKMAILDVEPQALKILRTAEFTPYVVFIAAPSLQNIADY-----------DGSLERLAKESEMLRQLYGHFFDLTIVNNDISETIATLETAIDRVHTTPQWVPVSWLY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::*::**:***************:*****:**:.**************:****** ******:*******************:**********:*:*****:*:** **********.**************:*:*:****:* *.***: :*********** **** .. : : **** **:******.*. *** ****.**:*.:**** *** *: ** :.: :*: .::. :* ** .***** :** :* .*::: *.*:***:::**: : **.:***:*:::********** * ... :::.:*. ::* . :. *. .**.::**.*::*::* *. * *.*:.:::*::** :*:*:*:* * :.: * *.::** *.::***::*. . .. :** *:*: **: ***::*.***::**.::*:****** ******. :..:* ::::***********************.: .:***************.***:********* .* :*:* ***:**** ***:*********: ..** *:*****:*:* .*:**** :*** *:****:***.****:***.:*:. *:*************:** :::****** ..*: **:**** :******** *:********:*. *:**********************:*:*:::**********.* :****:.*:*****:** **. *:*****:********:*:***:** :* :***********:******.*:*******:: .. * **:** ***::*:: *.*:** **:**:*.*** ** *:: * ::.*******:*", "identical_positions": 552, "similar_positions": 224, "identity": "58.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020806-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51577-1", "uniprot_id": "P2RX4_RAT", "id": "P51577-1", "name": "P2X purinoceptor 4", "aln": "---MAGCCSVLGSFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSVVSSVTTKAKGVAVTNTSQLGFRIWDVADYVIPAQEENSLFIMTNMIVTVNQTQSTCPEIPDKTSICNSDADCTPGSVDTHSSGVATGRCVPFNESVKTCEVAAWCPVENDVGVPTPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTSYLKSCIYNAQTDPFCPIFRLGTIVEDAGHSFQEMAVEGGIMGIQIKWDCNLDRAASLCLPRYSFRRLDTRDLEHNVSPGYNFRFAKYYRDLAGKEQRTLTKAYGIRFDIIVFGKAGKFDIIPTMINVGSGLALLGVATVLCDVIVLYCMKKKYYYRDKKYKYVEDYEQGLSGEMNQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJX6-1", "uniprot_id": "P2RX4_MOUSE", "id": "Q9JJX6-1", "name": "P2X purinoceptor 4", "aln": "---MAGCCSVLGSFLFEYDTPRIVLIRSRKVGLMNRVVQLLILAYVIGWVFVWEKGYQETDSVVSSVTTKAKGVAVTNTSQLGFRIWDVADYVVPAQEENSLFIMTNMIVTVNQTQGTCPEIPDKTSICDSDANCTLGSSDTHSSGIGTGRCVPFNASVKTCEVAAWCPVENDAGVPTPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTSYLKSCIYNARTDPFCPIFRLGQIVADAGHSFQEMAVEGGIMGIQIKWDCNLDRAASHCLPRYSFRRLDTRDLEHNVSPGYNFRFAKYYRDLAGNEQRTLTKAYGIRFDIIVFGKAGKFDIIPTMINVGSGLALLGVATVLCDVIVLYCMKKRYYYRDKKYKYVEDYEQGLSGEMNQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99571-1", "uniprot_id": "P2RX4_HUMAN", "id": "Q99571-1", "name": "P2X purinoceptor 4", "aln": "---MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSVVSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCPEIPDATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVKTCEVAAWCPVEDDTHVPQPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVENAGHSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAKYYRDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLCDIIVLYCMKKRLYYREKKYKYVEDYEQGLASELDQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F8W463-1", "uniprot_id": "P2X4A_DANRE", "id": "F8W463-1", "name": "P2X purinoceptor 4a", "aln": "MSESVGCCDSVSQCFFDYYTSKILIIRSKKVGTLNRFTQALVIAYVIGYVCVYNKGYQDTDTVLSSVTTKVKGIALTNTSELGERIWDVADYIIPPQEDGSFFVLTNMIITTNQTQSKCAENPTPASTCTSHRDCKRGFNDARGDGVRTGRCVSYSASVKTCEVLSWCPLEKIVDPPNPPLLADAENFTVLIKNNIRYPKFNFNKRNILPNINSSYLTHCVFSRKTDPDCPIFRLGDIVGEAEEDFQIMAVHGGVMGVQIRWDCDLDMPQSWCVPRYTFRRLDNKDPDNNVAPGYNFRFAKYYKNSDGTETRTLIKGYGIRFDVMVFGQAGKFNIIPTLLNMGAGLALLGLVNVICDWIVLTFMKRKQHYKEQKYTYVDDF--GLLHNEDK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*** :. :*:* *.:*::***:*** :** .* *::*****:* *::****:**:*:******.**:*:****:** ********::*.**:.*:*::**:*:* ****. *.* * :: * *. .*. * .::..*: *****.:. ******* :***:*. . * *.:* *****:*:**** ******.********.::**. *::. :*** ******* ** :* ..** ***.**:**:*:.***:** . * *:***:*****.:* ::**:***********:: *.* *** *.******::***:****:****::*:*:******:..*:** *** **:: :*:::**.**:*: ** : ::", "identical_positions": 220, "similar_positions": 112, "identity": "56.27%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020806-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06211-1", "uniprot_id": "ESR1_RAT", "id": "P06211-1", "name": "Estrogen receptor", "aln": "MTMTLHTKASGMALLHQIQGNELEPLNRPQLKMPMERALGEVYVDNSKPAVFNYPEGAAYEFNAAAAAAAAGASAPVYGQSSITYGPGSEAAAFGANSLGAFPQLNSVSPSPLMLLHPPPHVSPFLHPHG------HQVPYYLENEPS---AYAVRDTGPPAFYRSNSDNRRQNGRERLSSSSEKGNMIMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDLEGRNEMGTSGDMRAANLWPSPLVIKHTKKN--SPALSLTADQMVSALLDAEPPLIYSEYDPSRPFSEASMMGLLTNLADRELVHMINWAKRVPGFGDLNLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKINDTLIHLMAKAGLTLQQQHRRLAQLLLILSHIRHMSNKGMEHLYNMKCKNVVPLYDLLLEMLDAHRLHAP--ASRMGVPPEEPSQSQLTTTSSTSAHSLQTYYIPPEAEGFPNTI----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19785-1", "uniprot_id": "ESR1_MOUSE", "id": "P19785-1", "name": "Estrogen receptor", "aln": "MTMTLHTKASGMALLHQIQGNELEPLNRPQLKMPMERALGEVYVDNSKPTVFNYPEGAAYEFNAAAAAAAA-ASAPVYGQSGIAYGPGSEAAAFSANSLGAFPQLNSVSPSPLMLLHPPPQLSPFLHPHG------QQVPYYLENEPS---AYAVRDTGPPAFYRSNSDNRRQNGRERLSSSNEKGNMIMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDLEGRNEMGASGDMRAANLWPSPLVIKHTKKN--SPALSLTADQMVSALLDAEPPMIYSEYDPSRPFSEASMMGLLTNLADRELVHMINWAKRVPGFGDLNLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHRRLAQLLLILSHIRHMSNKGMEHLYNMKCKNVVPLYDLLLEMLDAHRLHAP--ASRMGVPPEEPSQTQLATTSSTSAHSLQTYYIPPEAEGFPNTI----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P03372-1", "uniprot_id": "ESR1_HUMAN", "id": "P03372-1", "name": "Estrogen receptor", "aln": "MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQ-----VYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHG------QQVPYYLENEPS---GYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKN--SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAP--TSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P57717-1", "uniprot_id": "ESR1_DANRE", "id": "P57717-1", "name": "Estrogen receptor", "aln": "----MYPKEE------HSAGGISSSVN---------------YLDG----AYEYPN-PTQTFGTSSPAEPA----------SVGYYPAP-----PDPHEEHLQTLGGGSSSPLMFAPSSPQLSPYLSHHGGHHTTPHQVSYYLDSSSSTVYRSSVVSSQQAAVGLCEELCSATDRQELYTGSRAAG--GFDSGKETRFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYVCPATNQCTIDRNRRKSCQACRLRKCYEVGMMKGGIRKDR-GGRSVRRERRRSSNEDRDKSSSDQCSRAGVRTTGPQDKRKKRSGGVVSTLCMSPDQVLLLLLGAEPPAVCSRQKHSRPYTEITMMSLLTNMADKELVHMIAWAKKVPGFQDLSLHDQVQLLESSWLEVLMIGLIWRSIHSPGKLIFAQDLILDRSEGECVEGMAEIFDMLLATVARFRSLKLKLEEFVCLKAIILINSGAFSFCSSPVEPLMDNFMVQCMLDNITDALIYCISKSGASLQLQSRRQAQLLLLLSHIRHMSNKGMEHLYRMKCKNRVPLYDLLLEMLDAQRFQSSGKVQRVWSQSEKNPPSTPTTSSSSSNNSPRGGAAAIQSNGACHSHSPDP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.* . : *. ..:* *:*. .::**: .: *.:::.* . .: * *.. : *.. *.****: ..*::**:* ** :**.***:...* :* .: .*. :. . :* :.: * ::*.****:****.******************************:**********:**************************** *** ::::*:*.. *.*.: .: **. ..* ::.:.. :*.::.**:: **.**** : *. . :**::* :**.****:**:****** ***:**** **.*****:***.:***:*****:***:. ****:** :*:***.:*:*****.********* :*** ::*: *******:***:***.::* **.::.* :: :: :**:*.*:**: ::*:* :** * :* *****:**************** ***** *************:*:::. ..* *: : :*:.*:* :* : . :::* : ", "identical_positions": 280, "similar_positions": 165, "identity": "45.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020808-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZU86-1", "uniprot_id": "D3ZU86_RAT", "id": "D3ZU86-1", "name": "", "aln": "---------------------------------MLFSLNEWLWQETYWLPPNVTWAQLED--RDGL-----VFAHPHHVLAALPIALVLVAMRIIFERFVALPLSRWMGVQDPIRRKIKPNPVLEKYFLRMKQR-PVETQMVLLASQCGLTLRQIQRWFRRRRNQDRPCLSKKFCEASWRFVFYLCSFVGGTSILYH-ESWLWTPALCWENYPHQTLNLALSWWYLLELGFYISLLITLPFDIK--RKDFKEQVAHHFVTVGLIVFSYSVNLLRIGSVVLLLHDCSDYLLEGCKMLNYAHFQRGCDTLFIIFSLVFFYTRLVFFPTEVIYTAVFDS-----------IKNSGPFFGYYFFIVLLGMLQILHVYWFCLILRMICSFLRKGQMREDIRS-DVE-ESDSSDDEAVSEGP---QLKNGMARGSRAAITN----GPRSRAAACLTNGHTRAT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D6J1-1", "uniprot_id": "CERS4_MOUSE", "id": "Q9D6J1-1", "name": "Ceramide synthase 4", "aln": "---------------------------------MSFSLSEWLWQETYWLPPNVTWAELED--RDGL-----VFAHPHHVLAAFPVALVLVAVRIVFERFVALPLSRWMGVQDPIRRKIKPNPVLEKYFLRMKQC-PEETQMVLLASQCGLTLRQTQRWFRRRRNQDRPSLSKKFCEACWRFVFYLCSFVGGTSILYH-ESWLWSPSLCWENYPHQTLNLSLYWWYLLELGFYLSLLITLPFDVK--RKDFKEQVVHHFVAVGLIGFSYSVNLLRIGAVVLLLHDCSDYLLEGCKILNYAHFRRGCDALFIMFALVFFYTRLIFFPTQVIYTSVYDS-----------IKNSGPFFGYYFFIVLLVMLQILHVYWFCLILRMLYSFLHKGQMTEDIRS-DVE-EPDSSDDEPVSEGP---QLKNGMARGSRVAVTN----GPRSRAAACLTNGHTRAT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HA82-1", "uniprot_id": "CERS4_HUMAN", "id": "Q9HA82-1", "name": "Ceramide synthase 4", "aln": "---------------------------------MLSSFNEWFWQDRFWLPPNVTWTELED--RDGR-----VYPHPQDLLAALPLALVLLAMRLAFERFIGLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHR-PKEPQLSLLAAQCGLTLQQTQRWFRRRRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYH-ESWLWAPVMCWDRYPNQTLKPSLYWWYLLELGFYLSLLIRLPFDVK--RKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHDSSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTTYYES-----------ISNRGPFFGYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRS-DVE-ESDSSEEAAAAQEPL--QLKNGAAGGPRPAPTD----GPRSRVAGRLTNRHTTAT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TEC1-1", "uniprot_id": "A0AB32TEC1_DANRE", "id": "A0AB32TEC1-1", "name": "", "aln": "----------------------MCIPLINGFMQLEDNINRWLWREDFWLPPGVTWKDIAEGTSDGS-----RHPVPRDLLISFPLALGFIALRFVFERVVALPLSRRLGVRDRVRLHITPIPKLEAFYLQKKKTEPSQEDLQALVKLCGLSERQIQSWLRRRRIQDRPANSRKFSEASWRFGFYLIIFSAGLISLIH-TPWFWDHRECWSGYPAQAVAEAQYWYYIIELSFYLSLLLCVSVDIK--RKDFQEQIIHHIATIFLIAFSYCANYVRVGTLVMLVHDSSDFLLESAKMFNYAGWRKTCDALFVVFAAVFLVTRLIVFPFRIVYTAVVDS-----------LDVFSPYPGYYFFNGLLLVLQALHIFWAWLILRMVHKFVFLGKVERDERS-DDESEPDEDDEVGEEEEERSWEHKKGALNSKLASLANNCVLNNLTNQRQKMNSRTLKER", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W423-1", "uniprot_id": "Q9W423_DROME", "id": "Q9W423-1", "name": "", "aln": "-------------------------------MDILNEFSNVFWSTHIWLPPNTTWADIAPGSRPDV-----VHANYKDLIWPIPFAAVVMLVRYTLERFWISPVGKSLGIRSSRPKKAANVPILEKTYAKSTRL--DKKKLVPLSKQTDMSEREIERWWRLRRAQDKPSTLVKFCENTWRCIYYLYSFIFGVIVLWD-KPWFWDVKSCWYGYPHQSISNDIWWYYMISMSFYWSLTGTQFFDVK--RKDFWQMFIHHMVTLLLMSLSWVCNLHRVGSLVLVVHDCADIFLEAAKLTKYAKYQKLCDAIFAIFTVVWIVTRLGFYP-RIIYSSSVEA-----------PRILPMFPAYYIFNSLLLMLLVLHVIWTYMILKIVVDSLQKGLMSGDIRSSDSEDLTDSSGNARLTNGSARSKNKSISSAPSDKGSAG----GAGSRAGARVATTERREE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38703-1", "uniprot_id": "LAG1_YEAST", "id": "P38703-1", "name": "Ceramide synthase LAG1", "aln": "-MTSATDKSIDRLVVNAKTRRRNSSVGKIDLGDTVPGFAAMPESAASKNEAKKRMKALTGDSKKDSDLLWKVWFSYREMNYRHSWLTPFFILVCVYSAYFLSGNRTESNPLHMFVAISYQVDGTDSYAKGIKDLSFVFFYMIFFTFLREFLMDVVIRPFTVYLNVTSEHRQKRMLEQMYAIFYCGVSGPFGLYIMYHSDLWLFKTKPMYRTYPVITNPFLFKIFYLGQAAFWAQQACVLVLQLEKPRKDYKELVFHHIVTLLLIWSSYVFHFTKMGLAIYITMDVSDFFLSLSKTLNYLNS-VFTPFVFGLFVFFWIYLR-HVVNIRILWSVLTEFRHEGNYVLNFATQQYKCWISLPIVFVLIAALQLVNLYWLFLILRILYRLIWQGIQKDERSDSDSDESAE------NEESKEKCE-------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P28496-1", "uniprot_id": "LAC1_YEAST", "id": "P28496-1", "name": "Ceramide synthase LAC1", "aln": "MSTIKPSPSNNNLKVRSRPRRK-SSIGKIDLGDTVPSLGTMFETKESKTAAKRRMQRLSEATKNDSDLVKKIWFSFREISYRHAWIAPLMILIAVYSAYFTSGNTTKTNVLHRFVAVSYQIGDTNAYGKGINDLCFVFYYMIFFTFLREFLMDVVIRPFAIRLHVTSKHRIKRIMEQMYAIFYTGVSGPFGIYCMYHSDLWFFNTKAMYRTYPDFTNPFLFKVFYLGQAAFWAQQACILVLQLEKPRKDHNELTFHHIVTLLLIWSSYVFHFTKMGLPIYITMDVSDFLLSFSKTLNYLDS-GLAFFSFAIFVVAWIYLR-HYINLKILWSVLTQFRTEGNYVLNFATQQYKCWISLPIVFVLIGALQLVNLYWLFLIFRVLYRILWRGILKDDRSDSESDEESDESSTTPTDSTPTKKDI------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . :.: . .. : . . : : : : :: * : : * : . *:: : ** : :*: . .*: . .::: ***. : **:.:: *: *: : ::* : : * :* :*. .* :* * :* :: * .:::: : : . :. *: * ::: * :*:::: : * : . : : .: . . ", "identical_positions": 28, "similar_positions": 86, "identity": "6.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020809-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8WZ75-1", "uniprot_id": "ROBO4_HUMAN", "id": "Q8WZ75-1", "name": "Roundabout homolog 4", "aln": "-------------------------------------MGSGGDSLLGGRGSLPLLLLLIMGG--MAQDSPPQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLS---MVPPDPHHLLPDGTLLLLQPPARGHAHDGQ-ALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQPRDMVAVVGEQFTLECGPPWGHPEPTVSWWKDGKPLALQPGRHTVSGGSLLMARAEKSDEGTYMCVATNSAGHRESRAARVSIQEPQDYTEPVELLAVRIQLENVTLLNPD----------PAEGPKPR----------------------------------------------------------PAVWLSWKVSGPAAPAQSYTALFRTQTAPGGQ-----------------GAPWAEELLAG-WQSAELGGLHWGQDYEFKVRPSSGRARGPDSNVLLLRLPEKVPSAPPQEVTLKP---GNGTVFVSWVPPPAENHNGIIRGYQVWSLGNTSLPPANWTVVGEQTQLEIATHMPG-SYCVQVAAVTGAGAGEPSRPVCLLLEQAMERATQEPSEHGPWTLEQLRATLKRPEVIATCGVALWLLLLGTAVCIHRRRRARVHLG---PGLYRYTSEDAILKHRMDHSDSQWLADTWRSTSGSRDLSSSSSLSSRLGADARDPLDCRRSLLSWDSRSPGVPLLPDTSTFYGSLIAELPSS--TPARPSPQVPAVRRLPPQLAQLSSPCSSS-----------DSLCSRRGLSSPRLSLAPAEAWKAKKKQELQHANSSPLLRGSHSLELRACELGNRGSKNLSQSPG-------AVPQALVAWRALGPKLLSSSNELVTRHLPPAPLFPHETPPTQSQQTQPPVAPQAPSSILLPAAPIPILSPCSPPSPQASSLSGPSPASSRLSSSSLS----SLGE--DQDSVLTPEEVALCLELS---EGEETPRNSVSPMPRAPSPPTTYGYISVPTASEFTDMGRTGGGVGPKGGVLLCPPRPCLTPTPSEGSLANGWGSASEDNAASARASLVSSSDGSFLADAHFARALAVAVDSFGFGLEPREADCVFIDASSPPSPRDEIFLTPNLSLPLWEWRPDWLEDMEVSHTQRLGRGMPPWPPDSQISSQRSQLHCRMPKAGASPVDYS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C310-1", "uniprot_id": "ROBO4_MOUSE", "id": "Q8C310-1", "name": "Roundabout homolog 4", "aln": "-------------------------------------MGSGGTGLLGTEWPLPLLLLFIMGG--EALDSPPQILVHPQDQLLQGSGPAKMRCRSSGQPPPTIRWLLNGQPLS---MATPDLHYLLPDGTLLLHRPSVQGRPQDDQNILSAILGVYTCEASNRLGTAVSRGARLSVAVLQEDFQIQPRDTVAVVGESLVLECGPPWGYPKPSVSWWKDGKPLVLQPGRRTVSGDSLMVSRAEKNDSGTYMCMATNNAGQRESRAARVSIQESQDHKEHLELLAVRIQLENVTLLNPE----------PVKGPKPG----------------------------------------------------------PSVWLSWKVSGPAAPAESYTALFRTQRSPRDQ-----------------GSPWTEVLLRG-LQSAKLGGLHWGQDYEFKVRPSSGRARGPDSNVLLLRLPEQVPSAPPQGVTLRS---GNGSVFVSWAPPPAESHNGVIRGYQVWSLGNASLPAANWTVVGEQTQLEIATRLPG-SYCVQVAAVTGAGAGELSTPVCLLLEQAMEQSARDPRKHVPWTLEQLRATLRRPEVIASSAVLLWLLLLGITVCIYRRRKAGVHLG---PGLYRYTSEDAILKHRMDHSDSPWLADTWRSTSGSRDLSSSSSLSSRLGLDPRDPLEGRRSLISWDPRSPGVPLLPDTSTFYGSLIAEQPSS--PPVRPSPKTPAARRFPSKLAGTSSPWASS-----------DSLCSRRGLCSPRMSLTPTEAWKAKKKQELHQANSSPLLRGSHPMEIWAWELGSRASKNLSQSPGPNSGSPGEAPRAVVSWRAVGPQLHRNSSELASRPLPPTPLSLRGAS-SHDPQSQCVEKLQAPSSDPLPAAPLSVLNSSRPSSPQASFLSCPSPSSSNLSSSSLS----SLEEEEDQDSVLTPEEVALCLELS---DGEETPTNSVSPMPRAPSPPTTYGYISIPTCSGLADMGRAGGGVGSEVGNLLYPPRPCPTPTPSEGSLANGWGSASEDNVPSARASLVSSSDGSFLADTHFARALAVAVDSFGLSLDPREADCVFTDASSPPSPRGDLSLTRSFSLPLWEWRPDWLEDAEISHTQRLGRGLPPWPPDSRASSQRSWLTGAVPKAGDSS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1RE66-1", "uniprot_id": "F1RE66_DANRE", "id": "F1RE66-1", "name": "", "aln": "MQVSAWMLWVAWLCTCSKAVRQCACPPDEQVAQRSEGKGHLRHRLMHQRASHRDRAHRRKGSRLVSEINLPRIVHHPSDVVVRVGSPATLSCRAEGNPEPTIQWLRNGQPLDTDKMDAQSQPIVLPDGSLFFFSVVPGRKG-------QSHEAVYACIAHNSIGNATSRNASLHIAALREDFRVQPSDVEVAIGEMATINCSPPVGHPEPNVTWRKDGILINSSNEHYTELKGKLIIAPAQKNDSGVYSCIASNMIGVRESRAARLSVLAKPVLLRKPEDVSVQLGESAQFFCEADGDPMPSIEWSREQGPLPNGRYLINPDHSLQIHYVTAQDMGRYSCTVENKLGVSVASAQLLVEDAGGTRLRDLHKELSALRVSLENVTVMSTASNMSQVMWKLQSFGSQPHYLEGFEVLYRSLLPASSDWTAQRVPQPSLHTHVGPLKRGYKYEFKVRPYGSSLYGRESNTRHLRVPEIVPSAAPQDVSITMPAERNDTVHLSWEPPPHDAHNGIIQGYQVWCVESEEQTSFNWTVDSGTHSIEIFTLLPSRLYWVTVAAVNGAGVGVQSDPYKLLIESRLEATP---YQTGILSMSHFVSVIKEPVFIGSVGTLLWCVLMITAVFLYRRHIRPANPSGKSSGLYRLESEDLIIKHRMAAPDSPWISGGWRPGSNSEPKQGLWTPSQENSGLRRTTLPITVKKDPNPLRS-AVPIVPDNCGVYGTFYVDLTGNGLKTFNSPGRCPRMPHGNSQLQNSETIRITEPIVKTAVVRELQALPWKRTLPAQPNMGVKKESWEKNVKRELHAVKSAPLMP-LNQQALAVCSAPNHQQRFSQHPAG--------GVSEPVKPLSSPRILHYSASLQLVDMLPSPPPLPMEDNHSLSSEDESTRSTKLTVDIGSQQSVCAASGLQGPASANTGCPNNHSPAQLSPSYSHLSTASFCLSTDDYQDTTLSTQGHTQYMEISPKPQGQSTSHQSTPSMPRPFSPTPTLGYICGPGDREMDEEQETVP-IGLRRATLRSTPSSCCS--EWEGSLWNGWGSVSESNVTSARTSIISSSDCSFINDANFARVLALTAESMSGNLSDFSPPASPLSVLFPPRE----CFGEVEPLPVWDWSTAWVEELEAQFKASRDPRRPAR--NSGIERWRGHLESPSHR---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *: . . *. : . *:*: **.* :.: .** : *::.*:* ***:** *****. * . . :****:*:: : .: .**:* * * :*.*.**.* * :*.*:***::** * ..:** .::*.** *:*:*.*:* *** : . : * ..*::: *:*.*.*.* *:*:* * *******:*: . * ::*:: . : :.: :** * .:: :* : :.*.. : :: . : .* .: *: : :.:* *: * .******* .. * :**. **:** ****.** *:: *.:*.:** *** : ***:*:*****.: . . .. **** . .:** * :*. * * ****.***.* * * **:*. :* :. : ::.:: :.::.* .*.: .. ** :*: :* ::**: .: . .**** *** *:**** .** *::. **. *.*. .. : *.. . * .* . . ** .**::**.. .**:: .: ... . ... : * : .:* .: :. ::* :* * : . *:*: : *:**: .:*:**: : : . . .: .: .:..* * : * .:. **..* : . : : : . . : . . *.*.::. . **:. * * ** .* **:.*:.: : :*:* :*:.*. :*...***. **..* ***. * : : .: :* . . * .* .* : **** *****.**.*..***:*::**** **: *::***.**::.:*:. .*. .. . .. ** : .**:*:* . *:*: * ... . *. :* . *. * : ", "identical_positions": 284, "similar_positions": 324, "identity": "24.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020809-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P42684-1", "uniprot_id": "ABL2_HUMAN", "id": "P42684-1", "name": "Tyrosine-protein kinase ABL2", "aln": "MGQQVGRVGEAP--GLQ-QPQPRGIRG-SSAARPSGRR-RDPAGRTTETGFNIFTQHDHFASCVEDGFE--GDKTGGSSPEALHRPYGCDVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVAEELGRAAS---SSSVVPYLPRLPILPSKTRTLKKQVENKENIEGAQDATENSASSLAPG-FIRGAQASSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKR---------------NAPTPPKRSSSFREMENQPHKKYELTGNFS-SVASLQHADGFSFTPAQQEANLVPPKCYGGSFAQRNLCNDD-GGGGGGSGTAGGGWSGITGFFTPRLIKKTLGLRAGKPTASDDTS--KPFPRSNSTSSMSSGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEESAAPSRERPKAKLLPRGATALPLRTPSGDLAITEKDPPGVGVAGVAAAPKGKEKNGGARLGMAGVPEDGEQPGWPSPAKAAPVLPT-THNHKVPVLISPTLKHTPADVQLIGTDSQGNKFKLLSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSICSDPTEEPTALTAGQSTSETQEGG-KKAALGAVPISGKAGRPVMPPPQVPLPTSSISPAKMAN-GTAGTKVALRKTKQAAEKISADKISKEALLECADLLSSALT---EPVPNSQLVDTGHQLLDYCSGYVDCIPQTRNKFAFREAVSKLELSLQELQVSSAAAGV----PGTNPVLNNLLSCVQEISDVVQR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4JIM5-1", "uniprot_id": "ABL2_MOUSE", "id": "Q4JIM5-1", "name": "Tyrosine-protein kinase ABL2", "aln": "MGQQVGRVGEAP--GLQ-QPQPRGIRG-SSAARPSGRR-RDPAGRTADAGFNVFTQHDHFASCVEDGFE--GDKTGGSSPEVLHRPFGCDAESQALNEAIRWSSKENLLGATESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTTDSKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTFKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECSREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVAEELGRTAS---SSSVVPYLPRLPLLPSKTRTLRKQGENKENLDGGLDAAESLASSSAPAGFIRSTQASSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKR---------------NAPTPPKRSSSFREMENQPHKKYELTGNFS-PVASLQNADGFSVAPSQQEPNLVPAKCYGGSFAQRNLCADDDSGGGGGSGTAGGGWSGITGFFTPRLIKKTLGLRAGKPTASDDTS--KPFPRSNSTSSMSSGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEEGAAPARERPKAKLLPRGATALPLRAP--DPAITESDSPGVGVAGVAAAPKGKERNGGTRLGVAGVPEDGEQLGWSSPAKAVAVLPT-THNHKVPVLISPTLKHTPADVQLIGTDSQGNKFKLLSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSTCSDPEEEPTAPPAGQHTPETQEGG-KKAAPGPVPSSGKPGRPVMPPPQVPLPTSSISPAKMAN-GTAGTKVALRKTKQAAEKISADKISKEALLECADLLSSAIT---EPVPNSQLVDTGHQLLDYCSGYVDSIPQTRNKFAFREAVSKLELSLQELQVSSTAAGV----PGTNPVLNNLLSCVQEISDVVQR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IYB8-1", "uniprot_id": "A0A0R4IYB8_DANRE", "id": "A0A0R4IYB8-1", "name": "Tyrosine-protein kinase", "aln": "MGQQVGRVGEGASSGIQTQPQSQQQQGRSNRASSSGRRPRDGGGGGSSTLTLTGTPPGRSAAAAVNIMPDPGINVFTLHSEALHRPFG--LDSTALTEAVRWSSKENLLGAAESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTASDGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYNLTVAVKTLKEDTMEVEEFLKEASVMKEVKHPNLVQLLGVCTLEPPFYIVTEYMPHGNLLDYLRECERDQVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWQWSPLDRPSFAEIHQAFETMFHDSSISEEVAEELCKTASGGQSGVAHTFGPDMPLLPSKSRGQKKHSENKENME---EAGPHGPAGLATSLFVGDGRSSS-SPALPRKQRDKSPSSLLEDCQDTTFTRDRKAGFFSSFMKKKSMSSSSATSSPQQQQNLPMPPKRSSSFREMETQPHKKYEPTAGFSGPPPPLPQTDGLSFSPSHGEGNHVQSRCCGATFGQKPSSSNS--GATSGQVGSSSSWGSLAGFFTPRLIKKTLGLRTGKSSGIDEVSGAKPFPRSNSTSSMSAGLPDLERMALTLPRN--RSKPPLERTSSTTSQPENGATRPSDAILRKLDEGTAQIRDRPKAKLLPRGVAGG-VRAP--------------GVGGEAESDSNTRGKDGQ----------DDRQGWSSPSKTSTLGSVNLHNHKVPVLISPTLKHSSGDAHLVGVDSQGNRFKLLSD-----SGDRDRPRLVKPKCAPPPPPMLRSLQHAYSADAADEVVSGNMEVNGDTIKRSGREVRGARPSIPPPQVPPAPVVPSSNNTTQTKLANGASSGGPGPTSAKPTLRRTRQQTERIPLEKISKEALLECAECLSSALQGNSELSSSSQVLDVGHQLLDYCSGYVDCIPQTRNKFAFREAVGKLELSLQELRACSTGGGVGLSGPGTSPALDNLHMCIKEISDVVQR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********.. *:* ***.: :* *. * .**** ** .* :.: * .: *:.. : : * :. .*.****:* :. **.**:***********:***********************************************************************************************************************::*.**********************************************************************************.*******:**************:****:**************************:**********.*::*.********************************************************************************************************************************************:*** ******* ********************* ::** *. . .: * :*:****:* :*: *****:: :* .:. *.. *: . ::** *******************.::* ******.*********: * * ************.******* *..** . ..* ::**:*.:*:: * * * .:* *.:*.*: . :. *. .*. :...*..::***************:**.:. *:.* *************:***: :***:***** *** **** **:****:.. *..* : :* :*.:* *:**********.:. :*:* **.* * : .... :.* .:: **.**:*: .: .. ***************:..*.:*:*.*****:*****: ***:**** ***********::* ***. .. . * :. : . .:.* :.* .:* . . **:*..: . *. . *. .. *.:.:* :**:*:* :*:*. :***********: ****: * ..**::*.*************.**************.*********:..*:..** ***.*.*:** *::********", "identical_positions": 805, "similar_positions": 218, "identity": "65.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020809-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70176-1", "uniprot_id": "PACA_MOUSE", "id": "O70176-1", "name": "Pituitary adenylate cyclase-activating polypeptide", "aln": "MTMCSGARLALLVYGIIMHSSVSCSP-AAGLSFPGIRPEDEAYDQDGNPLQDF-YDWDPPGVGSPASALRDAYALYYPADRR--DVAHEILNEAYRKVLDQLSARKYLQSVVARGAGENLGGSAVDDPAPLTKRHSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNKGRRIAYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13589-1", "uniprot_id": "PACA_RAT", "id": "P13589-1", "name": "Pituitary adenylate cyclase-activating polypeptide", "aln": "MTMCSGARLALLVYGIIMHNSVSCSP-AAGLSFPGIRPEEEAYDQDGNPLQDF-YDWDPPGAGSPASALRDAYALYYPADRR--DVAHEILNEAYRKVLDQLSARKYLQSMVARGMGENLAAAAVDDRAPLTKRHSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNKGRRIAYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18509-1", "uniprot_id": "PACA_HUMAN", "id": "P18509-1", "name": "Pituitary adenylate cyclase-activating polypeptide", "aln": "MTMCSGARLALLVYGIIMHSSVYSSPAAAGLRFPGIRPEEEAYGEDGNPLPDF-DGSEPPGAGSPASAPRAAAAWYRPAGRR--DVAHGILNEAYRKVLDQLSAGKHLQSLVARGVGGSLGGGAGDDAEPLSKRHSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNKGRRIAYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DE29-1", "uniprot_id": "Q9DE29_DANRE", "id": "Q9DE29-1", "name": "", "aln": "MITSSKTTLAFLIYGLLVQCNV-CSP----LSYPKIRMETAGFDEEGNSLTDVTFDSDQITIRSSPTVTEDAYTLFSPPSKRLERHADGMFNKAYRKALGQLSARKYLHTLMAKRVGG--GSTTEDDNEPLSKRHSDGVFTDSYSRYRKQMAVKKYLATVLGKRYRQRYRSKGRRLAYL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .* : **:*:**:::: .* .** * :* ** * .:.::**.* *. . : *..:. . * : : *..:* *. ::*:****.*.**** *:*::::*: * .. : ** **:******:*******************:******:** :.****:***", "identical_positions": 82, "similar_positions": 52, "identity": "45.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020812-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LKQ1-1", "uniprot_id": "A0ABK0LKQ1_RAT", "id": "A0ABK0LKQ1-1", "name": "", "aln": "-MCVQRAVSSGFPGLSASLKVQLSLPRDLGAENCLSENNHPDKPLKVLEELGKEFLTEYLEKLVQSNVLKLKEEEKQKFNNAERSDKRWVFVDVLKRKHNQVGKMLLQTFLNVD-------------------------SGSHHGEANLEMEE-----------------PE--ESVDTLKLCSSEEFTRLCREKKQEIYPIKETNGRTRKALIICNTEFKHLSL-RYGANIDISGMKGLLEELGYDVVVKEELTAEGMESEMKDFAALSEHQTSDSTFLVLMSHGTLQGLCGTMHSEATPDVLLYDTIYQIFNNCHCPGLRDKPKVIIVQACRGGNPGEVWIRESS--GAHSYRAVDLPRNMEADAVRMSHVEKDFIALYSTTPHHLSYRDKTRGSYFISKLISCFRIHACSCHLFDIFLKVQQSFEKAS----INSQMPTIDRATLTRYFYLFPGN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70343-1", "uniprot_id": "CASP4_MOUSE", "id": "P70343-1", "name": "Caspase-4", "aln": "----------------------------------MAENKHPDKPLKVLEQLGKEVLTEYLEKLVQSNVLKLKEEDKQKFNNAERSDKRWVFVDAMKKKHSKVGEMLLQTFFSVD-------------------------PGSHHGEANLEMEE-----------------PE--ESLNTLKLCSPEEFTRLCREKTQEIYPIKEANGRTRKALIICNTEFKHLSL-RYGANFDIIGMKGLLEDLGYDVVVKEELTAEGMESEMKDFAALSEHQTSDSTFLVLMSHGTLHGICGTMHSEKTPDVLQYDTIYQIFNNCHCPGLRDKPKVIIVQACRGGNSGEMWIRESS--KPQLCRGVDLPRNMEADAVKLSHVEKDFIAFYSTTPHHLSYRDKTGGSYFITRLISCFRKHACSCHLFDIFLKVQQSFEKAS----IHSQMPTIDRATLTRYFYLFPGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49662-1", "uniprot_id": "CASP4_HUMAN", "id": "P49662-1", "name": "Caspase-4", "aln": "----------------------------------MAEGNHRKKPLKVLESLGKDFLTGVLDNLVEQNVLNWKEEEKKKYYDAKTEDKVRVMADSMQEKQRMAGQMLLQTFFNID-------------------------QISPNKKAHPNMEAGP---------------PESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFDHLPP-RNGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGILEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDSP--ASLEVASSQSSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQKYSWCCHLEEVFRKVQQSFETPR----AKAQMPTIERLSMTRYFYLFPGN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q920D5-1", "uniprot_id": "CASPC_RAT", "id": "Q920D5-1", "name": "Caspase-12", "aln": "---------------------------------MAAKRTHERDPIYKIKGLAKDMLDGVFDDLMDKNVLNGDELLKIGEGASLILSKAENLVESFFEKTEMAGKIFAGHIANSDKQLSLQFPSDDEEDELQKMFTPSSASESRGKVEDEEMEVNVGVAHASHLMLTVPQGIQSTEVQDSLKLCSRDWFCTMKTERAEEIYPVMEKEGRTRLALIICNKKFDYLFD-RDDAETDILNMKELLQNLGYSVVIKENLTAQEMETELMKFAGRPEHQSSDSTFLVFMSHGILEGICGVKHRNKKPDVLHDDTIFTIFNNSNCPSLRNKPKILIMQACRGRHTGTIWVSTSKGIATADTDEECVLSHRWNNSITKAHVETDFIAFKSSTPHNISWKVGKSGSLFISKLIDCFKKYCWCYHLEEIFRKVQYSFEVPG----ELTQMPTIERVSMTRYFYLFPGN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q504J1-1", "uniprot_id": "CASPB_DANRE", "id": "Q504J1-1", "name": "Caspase b", "aln": "MEDITQLLSDVLEDLVESELKQFTRQLWIGVKPGVEPIPRGKLENKDRQDVVDSMVQQYSEDAGTITVQTLRKIKQNERAKRLESNLLKVQSQGQENKQNSEEPQPIPQIISQP--------------------IQQIISQPINNAGSEDLQP----------------IQADWQRPRQIIPCSQETKNTLLKAHGDDIYTPRSGTQRKGLALLITNIQFANTQHNRNGADRDEENAEWLLRSLGFAVIKYRNLSGKDIRRAVENFSKRREHEDADSTFIVIMSHGTRIDNKDAIVG-VSDDVYFIEETFSHLNSVNCPALIDKPKVILIQACRGGQSSGVLAQDSV-----------------FASDSWVHMEKDFVCFMSTMPNTFAYRNPIEGSFFISYIVDVFCSSAHRDDIMELFRKVTLRMEKDQRFQGQAKLLPCIERTSISKRFYLFPGL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : ...: :. .* . : : . : .* : . . ::: : : *. : : : ::**. . *. **:* * :* * .*: * . : **. *.: * .:*:.. :. : *: **: :****:*:**** . .. . ** : : :*. :* .* :***::::***** : . : * : *:*.**:.: *: *: .::: ** **: :: * . .: ::* ** :* :* *:* :::: ****** ", "identical_positions": 69, "similar_positions": 100, "identity": "15.07%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020812-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9T2-1", "uniprot_id": "D4A9T2_RAT", "id": "D4A9T2-1", "name": "", "aln": "-MNSHHV-VLTLASLMFLMCLPVSQSCNKALCASDVSKCLIQELCQCRPGEGNCPCCKECMLCLGALWDECCDCVGMCNPRNYSDTPPTSKSTVEELHEPIPSLFRALTEGDTQLNWNIVSFPVAEELTHHENLVSFLETVNQPHHQN-VSVPSNNVHAPFPSDKEHMCTVVYFDDCMSIHQCKISCESMGASKYRWFHNACCECVGPECIDYGSKTVKCMNCMF------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EP52-1", "uniprot_id": "TWSG1_MOUSE", "id": "Q9EP52-1", "name": "Twisted gastrulation protein homolog 1", "aln": "-MKSHYI-VLALASLTFLLCLPVSQSCNKALCASDVSKCLIQELCQCRPGEGNCPCCKECMLCLGALWDECCDCVGMCNPRNYSDTPPTSKSTVEELHEPIPSLFRALTEGDTQLNWNIVSFPVAEELSHHENLVSFLETVNQLHHQN-VSVPSNNVHAPFPSDKERMCTVVYFDDCMSIHQCKISCESMGASKYRWFHNACCECIGPECIDYGSKTVKCMNCMF------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZX9-1", "uniprot_id": "TWSG1_HUMAN", "id": "Q9GZX9-1", "name": "Twisted gastrulation protein homolog 1", "aln": "-MKLHYVAVLTLAILMFLTWLPESLSCNKALCASDVSKCLIQELCQCRPGEGNCSCCKECMLCLGALWDECCDCVGMCNPRNYSDTPPTSKSTVEELHEPIPSLFRALTEGDTQLNWNIVSFPVAEELSHHENLVSFLETVNQPHHQN-VSVPSNNVHAPYSSDKEHMCTVVYFDDCMSIHQCKISCESMGASKYRWFHNACCECIGPECIDYGSKTVKCMNCMF------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q98SR9-1", "uniprot_id": "TWS1B_DANRE", "id": "Q98SR9-1", "name": "Twisted gastrulation protein homolog 1-B", "aln": "-MGSSSS-SSVVLLLLLLSSLSIALACNKALCASDVSKCLIQELCQCRPADGNCSCCKECMLCLGSLWEECCDCVGMCNPRSMSESPATGRSTVEDLFQPIPSLFRALTEGDAPTHTLVLTLPLAEELQYQHNLHNYLETLHNTQHNNTTSVPENSIHSSYHTQ-DKQCTVVYFDECVSIRQCKQYCESMGGSKYRWFHNACCQCIGPECVDYGSKSVRCLNCLY------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W494-1", "uniprot_id": "Q9W494_DROME", "id": "Q9W494-1", "name": "", "aln": "MEIWRSLTVGTIVLLAIVCFYGTVESCNEVVCASIVSKCMLTQSCKCELKN--CSCCKECLKCLGKNYEECCSCVELCPKPNDTRNSLSKKSHVEDFDG-VPELFNAVATPDEGDSFGYNWNVFTFQVDFDKYLKGPKLEKDGHYFLRTNDKNLDEAIQERDNIVTVNCTVIYLDQCVSWNKCRTSCQTTGASSTRWFHDGCCECVGSTCINYGVNESRCRKCPESKGELGDELDDPMEEEMQDFGESMGPFDGPVNNNY-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZE5-1", "uniprot_id": "Q9VZE5_DROME", "id": "Q9VZE5-1", "name": "", "aln": "--------MKTLLTIYILLSFG-------------------------ELG----------LANMAQ---------------------MRKKSHTEEFEG-MPALFRAMSSS-PNDGYTYNWSVVSFSTN----------GKPGS---------------------GLNCTVLYLDQCTSWNKCRQTCLKTGATSYRWFHDGCCECVGELCMNYGVNESRCRLCPEP--GLEDEDD--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54356-1", "uniprot_id": "TSG_DROME", "id": "P54356-1", "name": "Protein twisted gastrulation", "aln": "-MQLLCYFVILFVGIAPWSSLANDDGCNEVVCGSVVSKCLITQSCQCKLND--CHCCKDCLNCLGELYIECCGCLDMCPKHKDVLPSLTPRSEIGDIEG-VPELFDTLTAE---DDEGWSTIRFSMRAGFKQRVQGGASGDAGNGNGNGNAGSAG----------VTLCTVIYVNSCIRANKCRQQCESMGASSYRWFHDGCCECVGENCLNYGINESRCRGCPEDQDQLLTADTVP-AEAEQDLERFFGNEEIEDEWGYGEEDEFS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : :. :* :: :* ** ::: .: ***:*.:.* .:*: * . *.:. ****:.**:*:* *::** : :* * ", "identical_positions": 25, "similar_positions": 34, "identity": "9.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020814-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R066-1", "uniprot_id": "CXAR_RAT", "id": "Q9R066-1", "name": "Coxsackievirus and adenovirus receptor homolog", "aln": "---MALLLCFVLLCGVADFTSSLSITTP-EQRIEKAKGETAYLPCKFTLEPEDQGPLDIEWLISPSDNQKVDQVIILYSGDKIYDNYYPDLKGRVHFTSNDVKSGDASINVTNLQLSDIGTYQCKVKKAPGVANRKFLLTVLVKPSGTRCFVDGSGEIGNDFKLKCEPKEGSLPLQYEWQKLSDSQKMPTPWLAEMTSPVISVKNASSEYSGTYSCTVQNRVGSDQCMLRLDVVPPSNRAGTIAGAVIGTLLALVLIGAILFCCHKKRREEKYEKEVHHDIREDVPPPKSRTSTARSY--IGSNHSSLGSMSPSNMEGYSKTQYNQVPSEDFERAP-QSPTLAPAKVAAPNLSRMGAVPVMIPAQSKDGSIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97792-1", "uniprot_id": "CXAR_MOUSE", "id": "P97792-1", "name": "Coxsackievirus and adenovirus receptor homolog", "aln": "---MARLLCFVLLCGIADFTSGLSITTP-EQRIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPSDNQIVDQVIILYSGDKIYDNYYPDLKGRVHFTSNDVKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKFLLTVLVKPSGTRCFVDGSEEIGNDFKLKCEPKEGSLPLQFEWQKLSDSQTMPTPWLAEMTSPVISVKNASSEYSGTYSCTVQNRVGSDQCMLRLDVVPPSNRAGTIAGAVIGTLLALVLIGAILFCCHRKRREEKYEKEVHHDIREDVPPPKSRTSTARSY--IGSNHSSLGSMSPSNMEGYSKTQYNQVPSEDFERAP-QSPTLAPAKVAAPNLSRMGAVPVMIPAQSKDGSIV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78310-1", "uniprot_id": "CXAR_HUMAN", "id": "P78310-1", "name": "Coxsackievirus and adenovirus receptor", "aln": "---MALLLCFVLLCGVVDFARSLSITTP-EEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSY--IGSNHSSLGSMSPSNMEGYSKTQYNQVPSEDFERTP-QSPTLPPAKVAAPNLSRMGAIPVMIPAQSKDGSIV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90Y50-1", "uniprot_id": "CXAR_DANRE", "id": "Q90Y50-1", "name": "Coxsackievirus and adenovirus receptor homolog", "aln": "MDMRTSFLCVTYVILLTGSACGLQITSTGQTSIEKASGESVKLDCQFTLASDDSGPLDIEWSLQPSDNQKEEKVVIVYSGDRAFEHYYDPLKGRVHFNSPDPKNGDASMNIMGLKATDTGTYQCKIKKVPGIASRKYLLTVMVRPSKPKCSAEGQTYVGKNMVLKCSSVEGTQPMEYIWERTSGNKLLPPLAILDKVTGTMTLKNATGDASGTYRCQAKNRVGTEECVVEVTITQPPNTAGIIAGVIICILLLLILLALILFCCCRARHKKKYEKEIAYEIREDVPPPKSRVSTARSFTSVGSQRSSLGSMSPSNLHEYSKPQYDKIPSEEYDRPPSHAPIPPPSRMAGPNLSRMGAIPVMIPAQNKDGSIV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :**.. : :.. : .*.**:. : ****.**:. * *:*** .:*.******* :.*:*** ::*:*:****: ::.** *******.* * *.****:*: .*: :* ******:**.**:*.:* *.*:*:** .:* .:*. :*.:: :**.. **: *::: *:: *..: :*. : : .: .:::***:.: **** * .:****:::*::.: :. *.* ** ***.:* ** * *:. *:*** : *:::*****: ::***********.*****: :**::**********:. ***.**:::***:::*.* ::* .*:::*.********:*******.******", "identical_positions": 178, "similar_positions": 129, "identity": "47.85%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020829-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZMU8-1", "uniprot_id": "D3ZMU8_RAT", "id": "D3ZMU8-1", "name": "", "aln": "------------------------MKEKSKNAARTRREKENSEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRVVFPEGLGEAWGHTSRTSPLDNVGRELGSHLLQTLDGFIFVVAPDGKIMYISETASVHLGLSQVELTGNSIYEYIHPADHDEMTAVLTAHQPY-------------------------HSHFVQEYEIERSFFLRMKCVLAKRNAGLTCGGYKVIHCSGYLKIRQYSLDMSPFDGCYQNVGLVAVGHSLPPSAVTEIKLHSNMFMFRASLDMKLIFLDSRVAELTGYEPQDLIEKTLYHHVHGCDTFHLRCAHHLLLVKGQVTTKYYRFLAKHGGWVWVQSYATIVHNSRSSRPHCIVSVNYVLTDTEYKGLQLSLDQISPSKPTFSYTSSSTPTITDNRKGAKSRLSSSKSKSRTSPYPQYSGFHTERSESDHDSQWGGSPLTDTASPQLLDPE-RPGSQHELSCAYRQFPDRGSLCYGFALDHSRLVEDR---HFHTQACEGGRCEAGRYFLGAPPAGRDPWWG-SRAALPLTKASPESRETYENSMPHITSVHRLHGRGHWDEDSVVS-SPDPGSASESGDRYRSEQYQNSPHEPSKIETLIRATQQMIKEEENRLQLRKAPPDQ-LASINGAGKKHSLCFANYQQPPPAGEVCHSSALTSTSPCDHIQQREGKMLSPHENDYDNSPTALSRISSPSSDRITKSSLILAKDYLHSDMSPHQTAGDHPAISPNCFGSHRQYFDKH-AYTLTGYALEHLYDSETIRNYSLGCNG-SHFDVTSHLRMQPDPAQGHKGTSVIITNGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61045-1", "uniprot_id": "SIM1_MOUSE", "id": "Q61045-1", "name": "Single-minded homolog 1", "aln": "------------------------MKEKSKNAARTRREKENSEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRVVFPEGLGEAWGHTSRTSPLDNVGRELGSHLLQTLDGFIFVVAPDGKIMYISETASVHLGLSQVELTGNSIYEYIHPADHDEMTAVLTAHQPY-------------------------HSHFVQEYEIERSFFLRMKCVLAKRNAGLTCGGYKVIHCSGYLKIRQYSLDMSPFDGCYQNVGLVAVGHSLPPSAVTEIKLHSNMFMFRASLDMKLIFLDSRVAELTGYEPQDLIEKTLYHHVHGCDTFHLRCAHHLLLVKGQVTTKYYRFLAKQGGWVWVQSYATIVHNSRSSRPHCIVSVNYVLTDTEYKGLQLSLDQISASKPTFSYTSSSTPTISDNRKGAKSRLSSSKSKSRTSPYPQYSGFHTERSESDHDSQWGGSPLTDTASPQLLDPE-RPGSQHELSCAYRQFPDRSSLCYGFALDHSRLVEDR---HFHTQACEGGRCEAGRYFLGAPPTGRDPWWG-SRAALPLTKASPESREAYENSMPHITSIHRIHGRGHWDEDSVVS-SPDPGSASESGDRYRTEQYQNSPHEPSKIETLIRATQQMIKEEENRLQLRKAPPDQ-LASINGAGKKHSLCFANYQQPPPTGEVCHSSALASTSPCDHIQQREGKMLSPHENDYDNSPTALSRISSPSSDRITKSSLILAKDYLHSDMSPHQTAGDHPAISPNCFGSHRQYFDKH-AYTLTGYALEHLYDSETIRNYSLGCNG-SHFDVTSHLRMQPDPAQGHKGTSVIITNGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P81133-1", "uniprot_id": "SIM1_HUMAN", "id": "P81133-1", "name": "Single-minded homolog 1", "aln": "------------------------MKEKSKNAARTRREKENSEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRVVFPEGLGEAWGHSSRTSPLDNVGRELGSHLLQTLDGFIFVVAPDGKIMYISETASVHLGLSQVELTGNSIYEYIHPADHDEMTAVLTAHQPY-------------------------HSHFVQEYEIERSFFLRMKCVLAKRNAGLTCGGYKVIHCSGYLKIRQYSLDMSPFDGCYQNVGLVAVGHSLPPSAVTEIKLHSNMFMFRASLDMKLIFLDSRVAELTGYEPQDLIEKTLYHHVHGCDTFHLRCAHHLLLVKGQVTTKYYRFLAKHGGWVWVQSYATIVHNSRSSRPHCIVSVNYVLTDTEYKGLQLSLDQISASKPAFSYTSSSTPTMTDNRKGAKSRLSSSKSKSRTSPYPQYSGFHTERSESDHDSQWGGSPLTDTASPQLLDPADRPGSQHDASCAYRQFSDRSSLCYGFALDHSRLVEER---HFHTQACEGGRCEAGRYFLGTPQAGREPWWG-SRAALPLTKASPESREAYENSMPHIASVHRIHGRGHWDEDSVVS-SPDPGSASESGDRYRTEQYQSSPHEPSKIETLIRATQQMIKEEENRLQLRKAPSDQ-LASINGAGKKHSLCFANYQQPPPTGEVCHGSALANTSPCDHIQQREGKMLSPHENDYDNSPTALSRISSPNSDRISKSSLILAKDYLHSDISPHQTAGDHPTVSPNCFGSHRQYFDKH-AYTLTGYALEHLYDSETIRNYSLGCNG-SHFDVTSHLRMQPDPAQGHKGTSVIITNGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q98SJ5-1", "uniprot_id": "SIM1A_DANRE", "id": "Q98SJ5-1", "name": "Single-minded homolog 1-A", "aln": "------------------------MKEKSKNAGRTRREKENSEFYELAKLLPLPSAITSQSDKASIIRLTTSYLKMRIVFPEGLGESWGHVSRTTSLENVGRELGSHLLQTLDGFIFVVAPDGKILYISETASVHLGLSQEELTGNSIYEYIHPADHDEMTAVLTAHQPY-------------------------HSHFVHEYEMERSFFLRMKCVLAKANAGLTCGGYKVIHCSGYLKIRQYSLDMSPFDGCYQNVGLVAVGHSLPPSAVTEIKLHSNMFMFRASLDMKLIFLDSRVAELTGYEPQDLIEKTLYHHVHSCDTFHLRCAHHLLLVKGQVTTKYYRFLAKQGGWVWVQSYATIVHNSRSSRPHCIVSVNYVLTDTEYKGLQLSLDQAASTKPSFTYNSPSNP-VTENRRVGKSRVSRTKTKTRLSPYSQYPGFPTDRSESDQDSPWGGSPLTDSASPQLLEQC----EGIESSCVYRQFSDPRSLCYGLPLTEDHHTSNELYSHPHSESCERGCCKAGRYFLGTPQPGREAWWGAARSVLPLPKSSPENGDSFEGVSPHIASIHSLQVRGHWDEDSAVSSAPDGGSASDSGDRFRADQCRSSPQEPSKIETLIRATQQMIKEEESRLQLRKLPTDVPLEPTNSLAK--SFHSTDFPQSAMQSVVCRG---------------PAQVISPAP-----SPVPLSRLSSPLPDRLSKGKDFLQNELSSSQLPLTGTCAVSPTPALYSLHP-RQYLEKHAAYSLTSYALEHLYEADTFRGYSLGCSGSSHYDMTTHLRK-AEQAPGHKGTSVIITNGS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P05709-1", "uniprot_id": "SIM_DROME", "id": "P05709-1", "name": "Protein single-minded", "aln": "MTNHRRVRKDCYESRLHDIAKTCAMKEKSKNAARTRREKENTEFCELAKLLPLPAAITSQLDKASVIRLTTSYLKMRQVFPDGLGEAWG-SSPAMQRGATIKELGSHLLQTLDGFIFVVAPDGKIMYISETASVHLGLSQVELTGNSIFEYIHNYDQDEMNAILSLHPHINQHPLAQTHTPIGSPNGVQHPSAYDHDRGSHTIEIEKTFFLRMKCVLAKRNAGLTTSGFKVIHCSGYLKARIYPDRGDGQGSLIQNLGLVAVGHSLPSSAITEIKLHQNMFMFRAKLDMKLIFFDARVSQLTGYEPQDLIEKTLYQYIHAADIMAMRCSHQILLYKGQVTTKYYRFLTKGGGWVWVQSYATLVHNSRSSREVFIVSVNYVLSEREVKDLVLNEIQTGVVK-----------------------------REPISPAAQAAQAAQAAQAAQAAQAAQAAHVAQAVQAQVVVVP-------------QQSVVVQPQCAG-------------------------------------ATGQPVGPG-TPVSLALS-ASPKLDPYFEPELPLQPAVTPVPP----TNNSSSS-SNNNNGVWHHHHVQQQQQSGSMDHDSLSYTQLYPPLNDLVVSSSSSVGGGTASSAG--GGSSASASSSGVYSTEMQYPDTT---------------------TGNLYYNNNNHYYYDYDATVDVATSMIRPFSANS----NSCSSSSESERQLSTGNASIVNETSPSQTTYSDLS-----HNFELSYFSDNSSQQHQHQQQQQ--HLMEQQHLQYQYATW--------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ********.********:** *********:***** ****:*********** ***:****:** * : . :***********************:************** *******:**** *:***.*:*: * *.: : *:*::*********** ***** .*:********** * *. . .. **:**********.**:******.*******.*******:*:**::***************:::*..* : :**:*::** ************:* ***********:******** ********:: * *.* *. * . * : ** .* . . :: . .: ::::...*:: :* . * * .*: * : *.*. :**: :* * .:: : ::* * : : ... . . : :* . ::. . * . :::: .... : . .. .. .. .. :: . .:: . . :::. :: .. :. *. . . .: . * : .: *.:: : .: : . * **: ", "identical_positions": 274, "similar_positions": 156, "identity": "33.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020916-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZT32-1", "uniprot_id": "A0A8I5ZT32_RAT", "id": "A0A8I5ZT32-1", "name": "Guanylate kinase", "aln": "----------MLRRPLVGLAVAALGRVPVDGMAGPRPVVLSGPSGAGKSTLLKKLFQEHGSVFGFSVSRECLRTLKGKE---------------------------LRDYYFVTREMMQRDIAAGDFIEHAEFSGNLYGTSKEAVRAVQAMNRICVLDVDLQGVRSIKKT-DLHPIYISVQPPSMDVLEQRLRQRNTETEESLAKRLAAAQADMESSKEPGLFDLVIVNDNLDEAYVTLKQALSEEIKKAEGTEHA----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64520-1", "uniprot_id": "KGUA_MOUSE", "id": "Q64520-1", "name": "Guanylate kinase", "aln": "-------------------------------MAGPRPVVLSGPSGAGKSTLLKKLFQEHSSIFGFSVSHTTRNPRPGEED--------------------------GKDYYFVTREMMQRDIAAGDFIEHAEFSGNLYGTSKEAVRAVQAMNRICVLDVDLQGVRSIKKT-DLCPIYIFVQPPSLDVLEQRLRLRNTETEESLAKRLAAARTDMESSKEPGLFDLVIINDDLDKAYATLKQALSEEIKKAQGTGHA----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16774-1", "uniprot_id": "KGUA_HUMAN", "id": "Q16774-1", "name": "Guanylate kinase", "aln": "-------------------------------MSGPRPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTTRNPRPGEEN--------------------------GKDYYFVTREVMQRDIAAGDFIEHAEFSGNLYGTSKVAVQAVQAMNRICVLDVDLQGVRNIKAT-DLRPIYISVQPPSLHVLEQRLRQRNTETEESLVKRLAAAQADMESSKEPGLFDVVIINDSLDQAYAELKEALSEEIKKAQRTGA-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U008-1", "uniprot_id": "A0AB32U008_DANRE", "id": "A0AB32U008-1", "name": "Guanylate kinase", "aln": "-------------------------------MSGPRPVVLSGPSGAGKSTLLKRLMKEYEGVFGFSVSHTTRNPRPGEEDGKGLNCLPMLLGATLLPVADVLSSVTSEDYHFVTKEKMQEGIDKDEFIENAEFSGNMYGTSKSSIEDVQAQNLICILDVDIQGVKNIKKT-DLNPIYISIQPPSMEILEKRLRDRQTETEDSLQKRLEAARIDMELSKEPGVFDIVIVNDDLEEAYEKLKSVLIEEIEKVQDAQK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTB3-1", "uniprot_id": "Q9VTB3_DROME", "id": "Q9VTB3-1", "name": "Guanylate kinase", "aln": "MISFLFIVNRALSSSSSSSSAAASLTSKKMTAPGPRPLVLCGPSGSGKSTLLKRLFAEFPSTFGFSISHTTRKPREGEEH--------------------------GVHYYFVERPEMEAAIAGDEFIETAEFTGNLYGTSKAAVREIQAQGRVCILDIEQKGVEQIKRT-DLNPILIFNNPPSIKELERRLRKRGSETEESLSKRLNAAQVELDYGLTPGNFHKIINNVDIDVAYEEFRNFVVQELKEQQKQGVSVNLN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15454-1", "uniprot_id": "KGUA_YEAST", "id": "P15454-1", "name": "Guanylate kinase", "aln": "-------------------------------MS--RPIVISGPSGTGKSTLLKKLFAEYPDSFGFSVSSTTRTPRAGEVN--------------------------GKDYNFVSVDEFKSMIKNNEFIEWAQFSGNYYGSTVASVKQVSKSGKTCILDIDMQGVKSVKAIPELNARFLFIAPPSVEDLKKRLEGRGTETEESINKRLSAAQAELAYA-ETGAHDKVIVNDDLDKAYKELKDFIFAEK-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **:*:.****:*******:*: *. . ****:* . *: .* ** :: * .:*** *:*:** **:: ::. :. . *:**:: :**..:* :* . : ***:. *::**. * :***:*: *** **: :: . .* .. :* * .:: ** ::. : * ", "identical_positions": 64, "similar_positions": 60, "identity": "24.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020916-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O00418-1", "uniprot_id": "EF2K_HUMAN", "id": "O00418-1", "name": "Eukaryotic elongation factor 2 kinase", "aln": "MADEDLIFRLEGVDGGQ-SPR----------AGHDGDSDGDSDDEEGYFICPITDDPSS--------------NQNVN-SKVNKYYSNLTKSERYSSSGSPANSFHFKEAWKHAIQKAKHMPDPWAEFHLEDIATERATRHRYNAVTGEWLDDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRDVYFEDVRLQMEAKLWGEEYNRHKPPKQVDIMQMCIIELKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTETGTDFGDGNLGVRGMALFFYSHACNRICESMGLAPFDLSPRERDAVNQNTKLLQSAKTILRGTEEKCGSPQVRTLS-GSRPPLLRPLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFSDLDNMASRDHDHLDNHRESENSGDSGYPSEKRGELDDPEPREHGHSYSNRKY-ESDEDSLGSSGRVCVEKWNLLNSSRLHLPRASAVALEVQRLNALDLEKKIGKSILGKVHLAMVRYHEGGRFCEKGEEWDQESAVFHLEHAANLGELEAIVGLGLMYSQLPHHILADVSLKETEENKTKGFDYLLKAAEAGDRQSMILVARAFDSGQNLSPDRCQDWLEALHWYNTALEMTDCDEGGEYDGMQDEPRYMMLAREAEMLFTGGYGLEKDPQRSGDLYTQAAEAAMEAMKGRLANQYYQKAEEAWAQMEE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O08796-1", "uniprot_id": "EF2K_MOUSE", "id": "O08796-1", "name": "Eukaryotic elongation factor 2 kinase", "aln": "MADEDLIFCLEGVDGGR-CSR----------AGHNADSDTDSDDDEGYFICPITDDHMS--------------NQNVS-SKVQSYYSNLTKTECG-STGSPASSFHFKEAWKHAIEKAKHMPDPWAEFHLEDIATEHATRHRYNAVTGEWLKDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRSVYFEDVQLQMEAKLWGEDYNRHKPPKQVDIMQMCIIELKDRPGQPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFYSHACNRICQSMGLTPFDLSPREQDAVNQSTRLLQSAKTILRGTEEKCGSPRIRTLS-SSRPPLLLRLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFGDLDNMGPRDHDRMDNHRDSENSGDSGYPSEKRSDLDDPEPREHGHSNGNRRH-ESDEDSLGSSGRVCVETWNLLNPSRLHLPRPSAVALEVQRLNALDLGRKIGKSVLGKVHLAMVRYHEGGRFCEKDEEWDRESAIFHLEHAADLGELEAIVGLGLMYSQLPHHILADVSLKETEENKTKGFDYLLKAAEAGDRHSMILVARAFDTGLNLSPDRCQDWSEALHWYNTALETTDCDEGGEYDGIQDEPQYALLAREAEMLLTGGFGLDKNPQRSGDLYTQAAEAAMEAMKGRLANQYYEKAEEAWAQMEE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F318-1", "uniprot_id": "E7F318_DANRE", "id": "E7F318-1", "name": "Eukaryotic elongation factor 2 kinase", "aln": "MAEEELMFSMEEVGSARDGSRNRCVKNRVCFQNSNASDDDDEEDEDDLRICPITDDIISPTKGFCEFPKNLAHNQQLSNSLPKNSFTYKNKNDNIEDVRFGSLTEKGRATWKHAIEKAKAMPDPWAEFHLEEMETERCTRYRYSAITGEWAKDEIFIKVSSQTFGKGAMRECFRAKKLSNFSHSHNWKSASNYVAKRYMETVDRSVYFEDVRLQMEAKLWGEEFNRHRPPKQVDIMQMCVVEMTTRPGSPLFHLEHYIEGKYTKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTSKGTDFGDGNLGVRGMALFFHSHLCNKICRSMGLTRFDLSPAEIAQLDCTNKLLQSAKTVLRGFEEQCGSPRVRTTSLGHMPVLLSRLSETSSVDESSDT--DSIPCSPLSMG-VSVGRSPMGWSFMNEMN---ETHRSQNTEQQDSENGGDSGYPSEKRSEGDPVEHHGQGRPIYNRHYSESDEDSVR---RLTEEKWSFYHSSRSHIHRPSCVAVEVERLNALLLEKKIGKSILGKVHLAMVRYHEAGRFCEKDEPWDQISAMYHLETAAMCGELEAIVALGQCYLQLPHHILPEIELEPSEENSQKGFRFLLQAAEAGDRPSMILVARAFDTGLKLPSDRAMDWTEAVHWYDSALKMTDYDEGGEFDGMQDEPRYLLLARLAEMYQEGGNNLDADPQRAGDLFTEAADAAMEAMKGRLANQYYMKAEEAWAMMEE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*:*:* :* *...: .* . :...* *.:*::. ******* * **::. * :. :: .*.: . : : : : :*****:*** ***********:: **:.**:**.*:**** .**::**::**.**:********:****** *:::**.*********:*.***.******:**********::***:***********::*:. ***.************* ****************************************************..******************:** **:**.****: ***** * :: ..:*******:*** **:****::** * . * ** ***.*. :: **. **:*.** * * . : *..:.::: .:.: ::::***.**********.: * * : :*:. **:: ******: *: *.*.: :.** *: *.*.**:**:***** * :*****:*************.******.* **: **::*** ** *******.** * *******.::.*: :***. *** :**:******* **********:* :*..**. ** **:***::**: ** *****:**:****:* :*** *** ** .*: :***:***:*:**:*************** ******* ***", "identical_positions": 449, "similar_positions": 165, "identity": "59.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020919-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TP48-1", "uniprot_id": "APMAP_RAT", "id": "Q7TP48-1", "name": "Adipocyte plasma membrane-associated protein", "aln": "----------------------------------------MTFLMLAVSLAIPLLGAMMLLESPIDPQSFSFKEPPFMFGVLQPNTKLRQAERLFENQLNGPESIVNIGDVLFTGTADGRVVKLENGEIETIARFGSGPCKTRDDEPTCGRPLGIRVGPNG-TLFVVDAYKGLFEVNPQKRSVKLLLSSETPIEGKKMS----FVNDLTITRDGRKIYFTDSSSKWQRRDYLLLVMEGTDDGRLLEYDTVTKEVKVLLDQLQFPNGVQLSPEEDFVLVAETAMARIRRVYVSGLMKGGADMFVENMPGFPDNIRPSSSGGYWVAAATIRANPGFSMLDFLSDKPFIKRMIFKLFS---------------------------QETVMKFVPRYSLVLEVSDSGAFRRSLHDPDGQVVTYVSEAHEHDGYLYLGSFRSPFICRLSLQSI------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D7N9-1", "uniprot_id": "APMAP_MOUSE", "id": "Q9D7N9-1", "name": "Adipocyte plasma membrane-associated protein", "aln": "MSEADGLRQRRPLRPQVVT-DDGQVPEVKEGSSFSGRVFRMTFLMLAVSLAIPLLGAMMLLESPIDPQSFSFKEPPFMFGVLHPNTKLRQAERLFENQLSGPESIVNIGDVLFTGTADGRVVKLENGEIETIARFGSGPCKTRDDEPTCGRPLGIRAGPNG-TLFVVDAYKGLFEVNPQKRSVKLLLSSETPIEGKKMS----FVNDLTVTRDGRKIYFTDSSSKWQRRDYLLLVMEATDDGRLLEYDTVTKEVKVLLDQLQFPNGVQLSPEEDFVLVAETTMARIRRVYVSGLMKGGADMFVENMPGFPDNIRPSSSGGYWVAAATIRANPGFSMLDFLSDKPFIKRMIFKMFS---------------------------QETVMKFVPRYSLVLEVSDSGAFRRSLHDPDGQVVTYVSEAHEHDGYLYLGSFRSPFICRLSLQSI------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HDC9-1", "uniprot_id": "APMAP_HUMAN", "id": "Q9HDC9-1", "name": "Adipocyte plasma membrane-associated protein", "aln": "MSEADGLRQRRPLRPQVVTDDDGQAPEAKDGSSFSGRVFRVTFLMLAVSLTVPLLGAMMLLESPIDPQPLSFKEPPLLLGVLHPNTKLRQAERLFENQLVGPESIAHIGDVMFTGTADGRVVKLENGEIETIARFGSGPCKTRDDEPVCGRPLGIRAGPNG-TLFVADAYKGLFEVNPWKREVKLLLSSETPIEGKNMS----FVNDLTVTQDGRKIYFTDSSSKWQRRDYLLLVMEGTDDGRLLEYDTVTREVKVLLDQLRFPNGVQLSPAEDFVLVAETTMARIRRVYVSGLMKGGADLFVENMPGFPDNIRPSSSGGYWVGMSTIRPNPGFSMLDFLSERPWIKRMIFKLFS---------------------------QETVMKFVPRYSLVLELSDSGAFRRSLHDPDGLVATYISEVHEHDGHLYLGSFRSPFLCRLSLQAV------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803F5-1", "uniprot_id": "APMAP_DANRE", "id": "Q803F5-1", "name": "Adipocyte plasma membrane-associated protein", "aln": "MNEPEGLRFRRLNRPHIIT-DETHEPQYKATSTYSGKVFRVTLLTMVAFLLLPLLVVVFVLESPIQPEVFSLNEPPLMTGCYEPNLKLRQAERLFEERLVGPESLANIGDVFYTGTADGKIVKIEGRNIHVLATIGKPPCGSREHEHTCGRPLGIRVGPNG-TLFVADAYLGLFEVNPVTGEVKSLVSTEKRIAGRRLG----FVNDLDVTQDGKKVYFTDSSSRWQRRDFMHLIMEATADGRVLEYDTETKEVNVMMENLRFPNGIQLFPDEESVLVAETTMARIKRVHVSGLNKGGMDTFIENLPGFPDNIRRSSSGGYWVAMSAVRPNPGFSMLDFLSQRPWLKKLIFKLFS---------------------------QDTLLKFVPRYSLVVELQSDGTCVRSFHDPQGLVSAYSSEAHEYSGHLYLGSFRSPYLCKLDLSKV------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VB46-1", "uniprot_id": "APMAP_DROME", "id": "Q9VB46-1", "name": "Adipocyte plasma membrane-associated protein Hemomucin", "aln": "--------------------------------MGLLYALRVRIMNFMIFFLLIILMPGLPPRTTFPFKDYIVTPPKDLKGALESNFHLEGAERLLEGRVYGPECLIARNNEIYTGIHGGEVIKLTSN-HVTHVTKIGQPCEDIYEESRCGRPLGLAFDTQGNNLIIADAYYGLWQVDLGTNKKTLLVSPAQELAGKSINRPAKIFNGVTVSKEG-DVYWTDSSSDFTIEDLVFASFANPS-GRLFKYNRSKNVSEVLLDELAFANGLALSPNEDFIVVAETGAMRLTKYHLKGAKAGQSEVFVDGLPGLPDNLTPDAEG-IWVPLVQSADSEHPNGFTLFTRFPSVRLFLARMLALFELPFRYLNSVYPNKFSQRFVHFVGHMESITVLAPKRTTVVRVDWNGNIVGSLHG-FDKSAATVSHVLEFQDFLFLGSPTNQYLARVKSPKAKQPTLKVRNVRVEGEGLEASIGVPPSKATPKPKAAPSTTTPKPTTTTTTTTPKPTTKTTTTTTTPKPTTTTTTKKPTTTTTTTTTTPKPTTTKPPTAKPSTTTTTTTTPKPTTTTTPTTPTPEPSKPKVKRTVPEKPAPVEEDIPSDTQPPKKEKLKVINKQGVNVEL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAQ9-1", "uniprot_id": "Q9VAQ9_DROME", "id": "Q9VAQ9-1", "name": "", "aln": "--------------------------------MGFLAALLKTSLFLVLFLGSLFLLPVLYPSTTFPFEQYFIKPARDLNGTLELNNHLNGARKLWKDQIFGPECLIVLEDKIYTGIHSGEVIRLNNEESVQPITKIGQPCDYIFDDELCGYPVGLALDTQGNNLIVSDAYYGIWQVDLETKKKTVLVPAEQILPGKGANRRAKLFNSLVISRQG-DIFWTDSFS----EDFVFAAFANPS-GRLFRYDRVKKTNEVLLDELSFANGLALSPSEDFIILAETTAMRLRRYYLKGSRAGESEVFVEGLPGCPDNLTADEEG-IWVPLSVASDSQNPNLFAVLAPYPRLRSFLARLVALMRLPLRVLNHIYPNDIAARLFHSFN--DLVIRNAPKRSTVVRVDWNGNIVRSLHG-FDRSASGISHVLEVKGHLYLGSPFNHYVAKVKLP---------------EEGLKSVKGN-------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :* : :.: : .. . : * . * :*. *.:* : :: ***.: : ::** .*.:::: . ** .: ** *:*: ..:* .*:: *** *:::*: . . . *:.. : *: . :.*.: ::::* .:::*** * .* : : . **::.*: .. :*::::* *.**: * * *: :::*** *: : ::.* * : *::.:** ***: . .* ** . . : .:: * :: :: ::.: : : .*: : *:.:. .* *:*. . : *.. * ...*:*** . ::.::. ", "identical_positions": 72, "similar_positions": 143, "identity": "11.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020919-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2Q1-1", "uniprot_id": "SC31A_RAT", "id": "Q9Z2Q1-1", "name": "Protein transport protein Sec31A", "aln": "-MKLKEIDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPHKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQKDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFA------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSN----RMHCSGLAWHPDVATQMVLASEDDRLPVVQMWDLRFASSPLRVLEN-HARGILAIAWSMADPELLLSCGKDAKILCSNPNT----GEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRIRVYSIMGGSIDGLRQKQVDKLSSSFGNLDPFGTGQPLPPLQIPQQTSQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVTGQPQQGAEQPRRQP-VFISQVVTEKDFLSRSEQLQHVVQSQGFISYCQKKIDASQTDFEKNVWSFLKVNFEEDSRGKYLELLGYRREDLGEKIALALNRVDGSDVALKDSDRVAQSDGEESPAEEGQLLG-ERIKEEKQECD---------------FLPSAGGGTFNISVSGDIDGLITRALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLAQTQK-KYFAKS--QSKITRLITAVVMKNWKEIVESCDLKNWR--EALAAVLTYAKPDEFSALCDLLGARLESEGDS--LLRTQACLCYICAGNVERLVACWTKAQ--------------DGSNPLSLQDLIEKVVILRKAVQLTQALDTNTVGALLAEKMSQYANLLAAQGSIAAALAFLPDN------TNQPDIVQLRDRLCRAQGRSVPGQESSRSSYEGQPLPKGGPGPLAG----HPQVSRVQSQ--------QYYPQVRIAPTVTTWSDRTPTALPSHPPAACPSDTQGGNPPPPGFIMHGNVVPNSPAPLP----TSPGHMHSQPPPYPQPQPYQPAQQYSLGTGGSAVYRPQQPVAPPASKRYPNAPYV--------------------SPVASYSGQPHMYTAQ-PASSPTSSSAPLPPPP-SSGASFQHGGPGAPPSSSAYALPPGT--TGTPPAASELPASQRT-------------GPQNGWNDPPALN--RVPKKKKLPEN---FMPPVPITSPI----------MNPGGDPQPQGLQQQPSASGPRSSHASFPQPHLAGGQPFHGIQQPLAQTGMPPSFSKPNTEG---APGAPIGNTIQHVQALPTEKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTKRKLDDASKRLECLYDKLRDQ-TLSPTIISGLHSIARSIETRNYSEGLTVHTHIVSTSNFSETSAFMPVLKVVLSQASKLGV---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UPL0-1", "uniprot_id": "SC31A_MOUSE", "id": "Q3UPL0-1", "name": "Protein transport protein Sec31A", "aln": "-MKLKEIDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPHKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQKDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFA------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSN----RMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLEN-HARGILAVAWSMADPELLLSCGKDAKILCSNPNT----GEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSIDGLRQKQVDKLSSSFGNLDPFGTGQPLPPLQIPQQSAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFESVAVPLQQGAEQQRRQP-VFISQVVTEKDFLNRSAQLQHAVQSQGFIGYCQKKIEASQTEFEKNVWSFLKVNFEEDSRGKYLELLGYRKEDLGQKIALALNKVDGPDVALKDSDQVAQSDGEESPAAEEQLLG-ERIKEEKQECD---------------FLPSAGG-TFNISVSGDIDGLITRALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLAQTQK-KYFAKS--QSKITRLITAVVMKNWREIVESCDLKNWR--EALAAVLTYAKPDEFSALCDLLGTRLEREGDS--LLRTQACLCYICAGNVERLVACWTKAQ--------------DGSSPLSLQDLIEKVVILRKAVQLTQALDTNTVGALLAEKMSQYASLLAAQGSIAAALAFLPDN------TNQPNIVQLRDRLCKAQGKPVSGQESSQSPYERQPLSKGRPGPVAG----HSQMPRVQTQ--------QYYP-------------------------------HGENPPPPGFIMQGNVIPNPAAPLP----TAPGHMPSQLPPYPQPQPYQPAQQYSFGTGGAAAYRPQQPVAPPASNAYPNTPYI--------------------SPVASYSGQPQMYTAQ-QASSPTSSSAASFPPP-SSGASFQHGGPGAPPSSSAYALPPGT--TGTPPAASELPASQRTENQSFQDQASILEGPQNGWNDPPALN--RVPKKKKMPEN---FMPPVPITSPI----------MNPSGDPQSQGLQQQPSTPGPLSSHASFPQQHLAGGQPFHGVQQPLAQTGMPPSFSKPNTEG---APGAPIGNTIQHVQALPTEKITKKPIPEEHLILKTTFEDLIQRCLSSATDPQTKRKLDDASKRLEFLYDKLREQ-TLSPTIINGLHSIARSIETRNYSEGLSVHTHIVSTSNFSETSAFMPVLKVVLSQASKLGV---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94979-1", "uniprot_id": "SC31A_HUMAN", "id": "O94979-1", "name": "Protein transport protein Sec31A", "aln": "-MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFA------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSN----RMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLEN-HARGILAIAWSMADPELLLSCGKDAKILCSNPNT----GEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFGTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLLG-EHIKEEKEESE---------------FLPSSGG-TFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQK-KYFAKS--QSKITRLITAVVMKNWKEIVESCDLKNWR--EALAAVLTYAKPDEFSALCDLLGTRLENEGDS--LLQTQACLCYICAGNVEKLVACWTKAQ--------------DGSHPLSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDN------TNQPNIMQLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAG----HHQMPRVQTQ--------QYYP-------------------------------HGENPPPPGFIMHGNVNPNAAGQLP----TSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPNTPYI--------------------SSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGT--TGTLPAASELPASQRT-------------GPQNGWNDPPALN--RVPKKKKMPEN---FMPPVPITSPI----------MNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFSKPNIEG---APGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTKRKLDDASKRLEFLYDKLREQ-TLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSETSAFMPVLKVVLTQANKLGV---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SYD5-1", "uniprot_id": "SC31A_DANRE", "id": "Q7SYD5-1", "name": "Protein transport protein Sec31A", "aln": "-MKLKEINRTAIQAWSPAQQHPIYLAAGTSAQQLDATFSTNASLEIFELDLADSALAMKSCGSFSSPHRYHKLVWGPHGIENQGLPSGVLIAGGENGNIILYDASKIIAGDSEVIISQSEKHTGAVRALDVNSFQSNLVASGGNESEIYIWDLNNFS------SPMTPGPKTQPQEDISCVAWNKQVQHILASASPSGKASVWDLRKNDLIIKVSDHSN----RMHCSGLAWNPEVATQLVLASEDDRMPVIQMWDLRFATSPLKVLEN-HTRGILAIAWSVADPELLLSCGKDNRILCWNPNT----AEVLYELPTSTQWCFDIQWCPRNPAVLSAAAFDGHISIYSIMGGSNDNANNLQADQLSSSFGNVDPFGTGKTLPPLQLPQQTSPQSTITPLKKPPKWIRRPVGASFAFGGKLVTLDNIKPTAQQ--PQQTAAHVVHISQVVTETDFIHRSNQLQTTLNAGNFLEYCQNKIETVQNEFERTVWSFLKVNFEEDARLKYLELLGYEKEELALKIASALEGNCKPKEADMDKEEVLAEEEAESDLDDIPVNEEEPVVEETSNTE---------------VPPAPASDAINLKVSQDIDGLITQALLTGDYEAAVNLCLHDNRMADGIILAIAGGPELLAKTQR-KYFSKT--ESKISKLISAVVMKDWLDILETCDLQNWK--EALAAVMTYAKPEEFSALCGLLGSRLESSEDV--ELQAQACLCYICAGTVEQLVSFWTKTQ--------------DSCSPLSLQELVEKVVVLQRAVEKAQGAVPADMGALLAEKMNQYASLLASQGSLQTAISYLPTN------TEQVSVQQLRERLSRALGQHQHLQQPAAAVTGIQKMHQRRPAAVPMQTYTQPQPPQVPAQPAAPAVPPQYYQQGRSATTVTSWSNQTPTALPSVPRQLVPSSDPQGDSTPPAFGLQS----PAMASVP----ASTPFMYSQ-----QYQNYPPVQQFTPSAGTPGIYQP-LPYASSAGAPLPPPPSS--------------------SSSAAVYPPQFMLSASSQASAPPQSFCP--PPAVSSGGCFQHGGPGSPTS---YLPPPGARAPGTQHEPALIPASQRTDG-FYQETAWGLEGPQNGWNDPPALS--RAAKKKKVPQH---FTPPAPITAPI----------MAPLGDPQAPAGMQTLQPQQQVPDQSAGPATFT----PIQ--QQPLGPR--NPSMPQGNMEG---APGAPIGDVIKPLQAIPTEKITKKPIPEEHMVLKTTFEGLIQKCLTAASDPQTKRKLDDAHKRLELLYDKLREQ-TLSPAIIGGLHNMAQSIECRSYADGLNIHTHIVSNSNFSETSAFMPVLKVVLTQANKLGV---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4LEZ1-1", "uniprot_id": "A0A0B4LEZ1_DROME", "id": "A0A0B4LEZ1-1", "name": "Protein transport protein Sec31A", "aln": "-MKIKELQKTVNIAWSPAQQQQILLAAGTAAQQFDS--NANSTLELYSPNFSDATYDLELRASVSSQYKFQKLIWSPVGP----HPSGLIVGGCEAGQINIYSADKLLAGKEEPLLKRQDKHTGAVSGLDFNPFQNNLLASCASESEILIWDLNNPE------TSMSPGTKTQPLEDVKNVAWNRQVQHILASVFST-RCVIWDLRKSQQIIKLSDSQS----RVRWHAIEWHPEAATQVWLASEDDQAPVVQLWDLRYATAPAKTYQI-HERGVLGMSWCLQDNDLMVSCGKDNRIYCWNPNTKIPEGEILSEVATTASWYSDVQFCPRNPALIASASLEGAVSIYSLHGGTHHLVQT--ANKIADSFPGMDQFAQEP-------IPQQATQVVYHDLAHAPKWMKRPCGVAFGFGGKLVSFN-------------GTSKTVKVQQLTTESALVDRANALERSLVDANYSDYCRQRADETPDQHGRYIWYFIKANFELNPKEEMLNLLGYNKDDIDSKFNKFIKETDGNSHSDVDTLTTRISTLTHSDSSEVECDQSTNYSTDNSQTQDNKFDGNAIDSQNHNDFATPPRPQFKVPSGDHSDSLIAEAILTGNVDAAVELCLEAQRIPEALIIASTAGIETLNRTQT-RYLLQQ--KNELSHVISALVSRDWLDFVNRCTVDSWK--EALVAALKHSE-RKVVDICERLGDRLLSECASSAEFTRNAMLCYICAGSIDKLVTAWYQLKRLEQQNPG------YKPNTTELQDLAEMVMLMCKSLE--QQGISVDLAGRFAGFLTEYGGLLASQGALTAALQYITTLGGGAAASESDVLQSLRDRINNAVNLDYTQPQAAVAAAPHGYQPTRGRGSFSQPQPSAPMPYGQPPN--------QYAQPSWP---------------AQVPPLQTSYPGAQQPQAPPQIFNPQPVKPEPLAQPP----RPLSNASSSGGPPPAGGASSSGGSGLSGRSKYVLDPSVAAPTSSYGMPYNPVPAP--------------------VPSAVPFGGGGVPGPAPQPASVPTYNSNAFNTNPIAAAQPYNPSPLMPAQQNQFVPGVNPIETMPPPAVPPVIQNVQRNP-----------TPPPGWNDPPALKSSRAPKPKPVVEPSAAIFHPLFPVDPN----------QNQNGYVDPSQYQHAAPLGGVPNTYYNPAAFNNNPQQQQQHQQSYLQPQQPAPGIQQPNWQGQQQTIGYTEQPAPIQQQRQPAPPKEKPPLPEEYIYLQTVLEELKNRCLGATNDPRTKRKFVDVVKRLENLYDCLRDG-KLTPTTVQYLNQIVQYIQISDYANAMEIHTQIAFGTDFAQCAGFMQGLKVLLQSASELQLVLR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38968-1", "uniprot_id": "SEC31_YEAST", "id": "P38968-1", "name": "Protein transport protein SEC31", "aln": "MVKLAEFSRTATFAWS--HDKIPLLVSGTVSGTVDANFSTDSSLELWSLLAADS---EKPIASLQVDSKFNDLDWS--------HNNKIIAGALDNGSLELYSTN--EANNAINSMARFSNHSSSVKTVKFNAKQDNVLASGGNNGEIFIWDMNKCTESPSNYTPLTPGQSMSSVDEVISLAWNQSLAHVFASAGSSNFASIWDLKAKKEVIHLSYTSPNSGIKQQLSVVEWHPKNSTRVATATGSDNDPSILIWDLRNANTPLQTLNQGHQKGILSLDWCHQDEHLLLSSGRDNTVLLWNPES----AEQLSQFPARGNWCFKTKFAPEAPDLFACASFDNKIEVQTLQNLTNTLDEQETETKQQESETDFWNNVSRE---------ESKEKPTVFHLQAPTWYGEPSPAAHWAFGGKLVQIT---------------PDGKGVSITNPKISGLESNTTLSEALKTKDFKPLINQRLVKVIDDVNEEDWNLLEKLSMDGTEEFLKEALAFDNDESDAQDDANNEKEDDGEEFFQQIETNFQPEG-------------------------------------------------DFSLSGNIEQTISKNLVSGNIKSAVKNSLENDLLMEAMVIALDSNNERLKESVKNAYFAKYGSKSSLSRILYSISKREVDDLVENLDVSQWKFISKAIQNLYPNDIAQRNEMLIKLGDRLKENGHR-----QDSLTLYLAAGSLDKVASIWLSEFPDLEDKLKKDNKTIYEAHSECLTEFIERFTVFSNFIN----GSSTINNEQLIAKFLEFINLTTSTGNFELATEFLNSLP-----SDNEEVKTEKARVLIASGKSLPAQNPATATTSKAKYTNAKTNKNVPVLPTPGMPSTTSIPSMQAPFYGMTPGASANALPPKPYVPATTTSAPVHTEGKYAPPSQPSMASPFVNKTNSSTRLNSFAPPPNPYATATVPATNVSTTSIPQNTFAPIQPGMPIMGDYNAQSSSIPSQPPINAVSGQTPHLNRKANDGWNDLPLKVKEKPSRAKAVSVAPPNILSTPTPLNGIPANAASTMPPPPLSRAPSSVSMVSPPPLHKNSRVPSLVATSESPRASISNPYAPPQSSQQFPIGTISTANQTSNTAQVASSNPYAPPPQQRVATPLSGGVPPAPLPKASNPYAPTATTQPNGSSYPPTGPYTNNHTMTSPPPVFNKPPTGPPPISMKKRSNKLASIEQNPSQGATYPPTLSSSASPLQPSQPPTLASQVNTSAENVSHEIPADQQPIVDFLKEELARVTPLTP-KEYSKQLKDCDKRLKILFYHLEKQDLLTQPTIDCLHDLVALMKEKKYKEAMVIHANIATNHAQEGGNWLTGVKRLIGIAEATLN----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 128, "similar_positions": 377, "identity": "9.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020919-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A8U9-1", "uniprot_id": "D4A8U9_RAT", "id": "D4A8U9-1", "name": "Protein unc-45 homolog B", "aln": "------MAEA-EATQLKEEGNQHFQRQDYKAATKSYSQALKLTK--DKALLATLYRNRAACGLKMESYAQAASDASRAIDINSADIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQETLRRLNTSIQEQLRVQFSTDSRVQTMFEILLNENSEADKREKAANNLIVLGREEAGAERIFQSNGVALLLQLMDAKR-PELVLAAVRTLSGMCSGHRARATAILHAVRIDRICSLMALENEEMSLAVCSLLQAIIDSLSGEDKREHRGKEEALVLDTKKDLKQITSHLLDMLVSKKVSGQGRDQALNLLNKNVPRKDLSIHDNSRTIYVVDNGLRKVLKVVGQVPDLP--SCLPLTDNTRMLASILINKLYEDLRCDPERDHFRKICEEYITSKFDPQDMDKNVNAIQTVSGILQGPFDLGNQLLGMKGVMEMMVALCGSEREADQLVAVEALIHASTKLSRATFIITNGVTLLKQIYKTTKNEKIKIRTLVGLCKLGSAGGSDYGLRQFAEGSTEKLAKQCRKWLCNTAIDTRTRRWAVEGLAYLTLDADVKDDFVQDIPALQAMFELAKT--SDKTILYSVANTLVNCTNSYDVKE-VVPELVQLAKFSKQHVPEEHPK-DKKDFVDLRVKRLLKAGVISALACMVKADSAILTDQTKELLARVFLALCDNPKDRGTIVAQGGGKALIPLALEGTDVGK---VKAAHGLAKIAAVSNPDIAFPGERVYEVVRPLVSLLDTQRDG-------------LQNYEALLGLTNLSGRSDKLRQKIFKEKA-----LPDIENYMFENHDQLRQAATECMCNMVLN-----KEVQERFLADGNDRLKLVVLLCGEDDHKLQNAAAGALAMLTAAHKKLCLKMTEVTTQWLEILQRLCLH-DQLSVQHRGLVIAYNLLSADAELARKLVETELLEILTVVGKQEPDETRAAVVQTARECLIKCMDYGFIKPVS--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CGY6-1", "uniprot_id": "UN45B_MOUSE", "id": "Q8CGY6-1", "name": "Protein unc-45 homolog B", "aln": "------MAEA-EAAQLKEEGNRHFQLQDYKAATKSYSQALKLTK--DKALLATLYRNRAACGLKMESYAQAASDASRAIDINSADIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQETLRRLNTSIQEQLRVQFSTDSRVQTMFEILLNENSEADKREKAANNLIVLGREEAGAERIFQSNGVALLLQLMNTQR-PELLLAAVRTLSGMCSGHRARATAILHAVRIDRICSLMALENEEMSLAVCNLLQAIIDSLSGEDKREHRGKEEALVLDTKKDLKQITSHLLDMLVSKKVSGQGRDQALNLLNKNVPRKDLSIHDNSRTIYVVDNGLRKILKVVGQVPDLP--SCLPLTDNTRMLASILINKLYDDLRCDPERDHFRKICEEYITSKFDPQDMDKNVNAIQTVSGILQGPFDLGNQLLGMKGVMEMMVALCGSEREADQLVAVEALIHASTKLSRATFIITNGVTLLKQIYKTTKNEKIKIRTLVGLCKLGSAGGSDYGLRQFAEGSTEKLAKQCRKWLCNTAIDTRTRRWAVEGLAYLTLDADVKDDFVQDIPALQAMFELAKARTSDKTILYSVANTLVNCTNSYDVKE-VVPELVQLAKFSKQHVPEEHPK-DKKDFVDLRVKRLLKAGVISALACMVKADSAILTDQTKELLARVFLALCDNPKDRGTIVAQGGGKALIPLALEGTDVGK---VKAAHGLAKIAAVSNPDIAFPGERVYEVVRPLVSLLDTQRDG-------------LQNYEALLGLTNLSGRSDKLRQKIFKEKA-----LPDIENYMFENHDQLRQAATECMCNMVLN-----KEVQERFLADGNDRLKLVVLLCGEDDHKLQNAAAGALAMLTAAHKKLCLKMTEVTTQWLEILQRLCLH-DQLSVQHRGLVIAHNLLSADAELARKLVESELLEILTVVGKQEPDEKRAAVVQTARECLIKCMDYGFIKPVS--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IWX7-1", "uniprot_id": "UN45B_HUMAN", "id": "Q8IWX7-1", "name": "Protein unc-45 homolog B", "aln": "------MAEV-EAVQLKEEGNRHFQLQDYKAATNSYSQALKLTK--DKALLATLYRNRAACGLKTESYVQAASDASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNTSIQEKLRVQFSTDSRVQKMFEILLDENSEADKREKAANNLIVLGREEAGAEKIFQNNGVALLLQLLDTKK-PELVLAAVRTLSGMCSGHQARATVILHAVRIDRICSLMAVENEEMSLAVCNLLQAIIDSLSGEDKREHRGKEEALVLDTKKDLKQITSHLLDMLVSKKVSGQGRDQALNLLNKNVPRKDLAIHDNSRTIYVVDNGLRKILKVVGQVPDLP--SCLPLTDNTRMLASILINKLYDDLRCDPERDHFRKICEEYITGKFDPQDMDKNLNAIQTVSGILQGPFDLGNQLLGLKGVMEMMVALCGSERETDQLVAVEALIHASTKLSRATFIITNGVSLLKQIYKTTKNEKIKIRTLVGLCKLGSAGGTDYGLRQFAEGSTEKLAKQCRKWLCNMSIDTRTRRWAVEGLAYLTLDADVKDDFVQDVPALQAMFELAKAGTSDKTILYSVATTLVNCTNSYDVKE-VIPELVQLAKFSKQHVPEEHPK-DKKDFIDMRVKRLLKAGVISALACMVKADSAILTDQTKELLARVFLALCDNPKDRGTIVAQGGGKALIPLALEGTDVGK---VKAAHALAKIAAVSNPDIAFPGERVYEVVRPLVRLLDTQRDG-------------LQNYEALLGLTNLSGRSDKLRQKIFKERA-----LPDIENYMFENHDQLRQAATECMCNMVLH-----KEVQERFLADGNDRLKLVVLLCGEDDDKVQNAAAGALAMLTAAHKKLCLKMTQVTTQWLEILQRLCLH-DQLSVQHRGLVIAYNLLAADAELAKKLVESELLEILTVVGKQEPDEKKAEVVQTARECLIKCMDYGFIKPVS--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DGE9-1", "uniprot_id": "UN45B_DANRE", "id": "Q6DGE9-1", "name": "Protein unc-45 homolog B", "aln": "----MTMGEIGDSVQLKEEGNKHFQAGEIDQAIDCYTKAIKTCKKEDKKALAVIYRNRSACFLKKENYSNAASDATKAIDVDAADIKALYRRCQAFEKLGKLDMAFKDVQRCATIEPKNKTFLETLRRLGAEIQQKLKTTFSTDSRVQNMFDILFSDEPDKEKREKAANNLIVLAREDAGAERIFQNNGVPLLMQLIDTGK-PEMILAAIRTLSGMCTGHRARATAIIHSVGISKLCSIMAVDNEEIALATANLFQCVNDSLSGGDKR-NYGKEEALVLDSSKDLKDILLALLEMIASKNVSGHGRDQALNLLTKNVPRQNKKSTDNSKCLFTIDHGLKKILKVCGQVPDLP--DQLPMTENTQLIASVLLSKLYDDLRCDPERDQFRDICDDYIKSKFDPNDMDKNIHAINTLSGILQGPFDLGNVLAGRQGVMEMMVALCGSEREVDQLVAVEALIHASTKTSKASFFISNGVSLLKEMYKKTKNEKIKIRALVGLCKLGSAGGDDYSMRQFAEGSTEKLAKQCRKWLCNPTLDVRTRKWAIEGLAYLTNDADVKDDFAEDEPAMRAMFELTKS--NDKTILYAVACTLVNCTNSYDKKE-IIPEMVQLAKFSKQHVPEQHPK-DKKDFIVRRVKRLLKAGVTSALAVMVKADNSILTDQTKEMLARVFLALTEDVKDRGIIVAQGGGKALIPLALEGTDKGK---IKASHALAKIAAVSNPEIAFPGERIYEVVRPLVSLLGTDRDG-------------MENFEALRGLTNLAGLNDKLRVKILKEKA-----LPEIENYMFEDHEQIRQAATECMCNLVCC-----KEVQDRYLEDGNDKLKLLVLLCGEDEEKLQRAAAGALAMLTAAQKKLAVKMTKVTEQWLEILQRLCIH-DNPEIQHRGLVTVFNMLDADDQLAKKLVESDMLEILTYVAKLEDNPKKQNAIDAARACLSKAMDNGLIKPFSN-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHW4-1", "uniprot_id": "Q9VHW4_DROME", "id": "Q9VHW4-1", "name": "", "aln": "MTNTINSEEVSDAGSYKDKGNEAFKASRWEEAVEHYGKAIKAGS--KHKELAVFYKNRAAAYLKLGKYENAVEDCTESLKAAPGDPKALFRRAQAYEALEKFEEAYKDATALFKADPGNKTVQPMLQRLHVVVEERSARNAKTSTKVKQMMDLTFDLATPIDKRRAAANNLVVLAKEQTGAELLYKDHCIAKVASLTKVEKDQDIYVNMVHLVAALCENSVERTKGVLTELGVPWFMRVLDQKHENCVSTAQFCLQTILNALSGLKNKPDSKPEKELCTRNNREIDTLLTCLVYSITDRTISGAARDGVIELITRNVHYTALEWAER----LVEIRGLCRLLDVCSELEDYKYESAMDITGSSSTIASVCLARIYENMYYDEAKARFTDQIDEYIKDKLLAPDMESKVRVTVAITALLNGPLDVGNQVVAREGILQMILAMATTDDELQQRVSCECLIAASSKKDKAKALCEQGVDILKRLYHS-KNDGIRVRALVGLCKLGSYGGQDAAIRPFGDGAALKLAEACRRFLIKPGKDKDIRRWAADGLAYLTLDAECKEKLIEDKASIHALMDLARG--GNQSCLYGVVTTFVNLCNAYEKQE-MLPEMIELAKFAKQHIPEEHEL-DDVDFINKRITVLANEGITTALCALAKTES----HNSQELIARVLNAVCGLKELRGKVVQEGGVKALLRMALEGTEKGK---RHATQALARIGITINPEVSFSGQRSLDVIRPLLNLLQQDCTA-------------LENFESLMALTNLASMNESVRQRIIKEQG-----VSKIEYYLMEDHLYLTRAAAQCLCNLVMS-----EDVIKMFEGN-NDRVKFLALLCEDEDEETATACAGALAIITSVSVKCCEKILAIAS-WLDILHTLIAN-PSPAVQHRGIVIILNMINAGEEIAKKLFETDIMELLSGLG-QLPDDTRAKAREVATQCLAAAERYRIIERSDNAEIPDVFAENSKISEIIDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P51534-1", "uniprot_id": "SHE4_YEAST", "id": "P51534-1", "name": "SWI5-dependent HO expression protein 4", "aln": "-------------MPLCEKGNDPIDSSTIDSLCAAFDKTLKSTP-------------------DVQKYNDAINTIFQLRQKSES---------------GKMPADLTNSEALKDRQ---------------KIEEILTRSYQDHSESRVHLSKLIQNDIP-----FALNLFEILSR-------------------------------SSIHVFVG-CFSNKDATIALLNELQIR-----IHYGEDTHVTYLLSIILQLLNKFKYNFKEVRFLVKELILRISEDEVKSMMLIIFAELQSSFQKDFDK-AVVDFMSSLIVEAEID---------VGNDPLSIIVKTLSELYPSL------TTLCSEIFLTKGLSKLFKKRVFEEQDLQFTKELLRLLSSACIDETMRT--YITENYLQLLERSLNVEDVQIYSALVLVKTWSFTK--------------------------LTCINLKQLSEIFINAISRRIMPKIEN------------------VNESAVKLEEVPKVEMS------------VEALAYLSLKASVKIMIRSNESFTEILLTMIKSQ-KMTHCLYGLLVIMANLSTLPEESNGSSQSINDLKNYADLKGPGADKVGAEKESKEDILLFNEKYILRTELISFLKREMHNLSPNCKQQVVRVIYNITRSKNFIPQCISQGGTTIILEYLANKQDIGEPIRILGCRALTRMLIFTNPGLIFKKYSALNAIPFLFELLPRSTPVDDNPLHNDEQIKLTDNYEALLALTNLASSETSDGEEVCKHIVSTKVYWSTIENLMLDENVPLQRSTLELISNMMSHPLTIAAKFFNLENPQSLRNFNILVKLLQLSDVESQRAVAAIFANIATTIPLIAKELLTKKELIENAIQVFADQIDDIELRQRLLMLFFGLFEVIPDNGTNEVYPLLQENQKLKDALNMSLKRGDSGPEFSAAIPVILAKIKV------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::** :. . : :::* . .* :* . . . . *: .: : ::: . :. : :. :. * * : :*.: :: . . * . : :: : : : .: : : : :. :. :: : .. ::. : :. : . .. : .::::. : . * ::.. .:: * : : : : :::.. : :* . :.. * . :*: .::: : :: :: : .: *..:: . . * : : :: ** : : : :.****: .*. * : .: . . :: : : **.: :.* . : .: .: :* :::. : * . . : : : : : * : * : : :: :.**: : : : :** . :: : : *: . :.*::: ** : * :.: *. ** . :*:*:* .****:. . . .: *. . ** ::::: : ::: : :.*:: .. . : ..:::. * .: : * *. :* :::. . :: : :: : : . :::* :: .:: . : . : . . : * . . .: .: : ", "identical_positions": 61, "similar_positions": 272, "identity": "6.15%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020925-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NYC9-1", "uniprot_id": "DYH9_HUMAN", "id": "Q9NYC9-1", "name": "Dynein axonemal heavy chain 9", "aln": "MRLAEERAALAAENADGEPGADRRLRLLGTYVAMSLRPAAGAWERCAGSAEAEQLLQAFLGRDAAEGPRPLLVVRPGPRGLAIRPGLEVGPESGLAGAKALFFLRTGPEPPGPDSFRGAVVCGDLPAAPLEHLAALFSEVVLPVLANEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQVKGKTLLPLPAGSEKMEFADSKSETVLDSIDKSVIYAIESAVIKWSYQVQVVLKRESSQPLLQGENPTPKVELEFWKSRYEDLKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVVAALAEAQDIHVHLIPLQRHLEALENAEFPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTVLLQEICNLLIQQASNYLSPEDLLRSEVEESQRKLQVVSDTLSFFKQEFQDRRENLHTYFKENQEVKEWDFQSSLVFVRLDGFLGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQQVQQMHEEFQEMYRLLSGSSSDCLYLQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGLEHAFKLLDIAGNLLERPLVARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSPVHKNMPTVAGGLRWAQELRQRIQGPFSNFGRITHPCMESAEGKRMQQKYEDMLSLLEKYETRLYEDWCRTVSEKSQYNLSQPLLKRDPETKEITINFNPQLISVLKEMSYLEPREMKHMPETAAAMFSSRDFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLNWKTEGICDYVTEITSSIHDLEQRIQKTKDNVEEIQNIMKTWVTPIFKTKDGKRESLLSLDDRHDRMEKYYNLIKESGLKIHALVQENLGLFSADPTSNIWKTYVNSIDNLLLNGFFLAIECSLKYLLENTECKAGLTPIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIFRIPSLVPRLSPQNGSPHYQVDLDGIPDLANMRRTLMERVQRMMGLCCGYQSTFSQYSYLYVEDRKEVLGQFLLYGHILTPEEIEDHVEDGIPENPPLLSQFKVQIDSYETLYEEVCRLEPIKVFDGWMKIDIRPFKASLLNIIKRWSLLFKQHLVDHVTHSLANLDAFIKKSESGLLKKVEKGDFQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPETVFKQLEELPEKWNNIKKVAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQMLDARHIEIQQMESTMASISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRTELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMKRRPVWTDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITHDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVSRAGILYINPADLGWNPPVSSWIEKREIQTERANLTILFDKYLPTCLDTLRTRFKKIIPIPEQSMVQMVCHLLECLLTTEDIPADCPKEIYEHYFVFAAIWAFGGAMVQDQLVDYRAEFSKWWLTEFKTVKFPSQGTIFDYYIDPETKKFEPWSKLVPQFEFDPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGKSVLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLSLKEITNVQYVSCMNPTAGSFTINPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKLGNFPASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQTQSPNLYCHFANGIGEPKYMPVQSWELLTQTLVEALENHNEVNTVMDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNRENCWKFFIDRIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIEPTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLMAPRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRPYLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENVRWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVTPALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKNKYGEDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKGRFIKIGDKECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNKTALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGELSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKALLEEILERVTDEFNIPELMAKVEERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQRGPTYVWTFNLKTKENPSKWVLAGVALLLQI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B1AR51-1", "uniprot_id": "B1AR51_MOUSE", "id": "B1AR51-1", "name": "", "aln": "MPGAKEQAALAES-GDEEPG-DPRLRLLGTFVARSLRPAAGTWERCAGTAEAGRLLQAFLDHNAASDPRPLLVVQSGPGGLVVTPGLDAGPEPSRARAKGLFFLRTKSEPPGNHSLRGTVLCGDLPAVPLEHLAPLLSEVIIPVLANEKNHLEWPHMVCQDIRHHAHTLKSDLLVIFEHMKGRTLLPLPVGSEKLEFVDGHSEPVSDAIDKSTLYAVESAVIKWSHQVQVVLKRESSQALIQGQNPTPKVELEFWKSRCEDLEHIYNQLMTIKVKGMAELLDKLQSSYLPAFKAMFRDVEAALTEAQDIHVHLLPLQQHLDILENVEFPKVKGRLRPLLHVVCLIWATCKWYRSPGRLTVLLQEICNLLIQQASNYLSPEDLLRSEVEESQKKLQVVSDTLSFFKQAFQDRREHLHTYFKEDSEVRVWDFQASLVFVRLDGFLGRVHMVEDLLKTALDLNNLEKLEFSGLRGNSLSQKVQRMHEEFEEMYKVFLDCSYDCLDPKGTEFENDVCEFNKRVEDLDRRLGTILIQAFDDAPDVEHAFKLLDITGTLIKRPLVAQDVSQKYLALIRMFSTELDAVRVIYSQHIQKEAEHGFSPVHKNMPTMAGGICWAQELRQRVKGPFGNFKNIPHLYLQSAEGKRMIQKYEDLLSLLEEYERRLYEDWCQTVSEKSQYNLSLPLLHRDPNTKQLSVNFNPQLISVLKEMNYLQPSEVKTIPETAAAMFSSREFYRQLVANLELMANWYNKVIKILLEVEFPLVEEELQNIDLRLRAAEETLSWKTEGIWDYAMQITNSIHDLEQRIQKTKDNVEEIQNIMKTWVSPIFKRKDGKKEWPLSLDDQQDHMEKYYSLIQESGLKIHALVQENLVLFAADPASSIWKSYVNYIDSMLLDGFFLAIECSLKYLLENTECKPGLTPVFEAQLNLVTPELVFHPSLDSGVKGGLYDIVQSLVTRIFAMPSLVPRLSPHSGSPHYQGDLEDMADLAGLRSVLMERVQNMMTLCCGYRNTLSQYSYLYVEDRKEILGQFLLYGHVLTPEEIEAHAEDGIPENPPLLHHFKDQIDSYEKLYEEVVSLEPTKVFDGWMRVDVRPFKASLLNTIKKWSLMFKQHLVDFVTNSLSDLDSFIRSTESGLLKRVEKGDFQGLVEIMGHLVTLKERQSSTDDMFEPLKQTIELLKSYEQELPETVFKQLEELPEKWKNMKKMAITVRQQVAPLQANEVALLRQRCSAFDDEQQQFQERFRKEAPFRFDSINPHQMLDAWHVEIQHMESTMATISKSADLFEVNVPDYKQLRQCRKEACQLKELWDTIGMVTSSIRAWEATSWRNISVEAMDSECKQFARHIRNLDKEFRSWDAFTGLESTVLNTLTSLRAVAELQNPAIRDRHWRQLMQATGVNFTMNQDTTLAHLLQLQLHHFEDEVRGIVDRAVKEMSMEKTLKELQTTWASMEFQYESHARTRVPLLQSDEDLIEVLEDNQVQLQNLMMSKYVAFFLEEVSSWQKKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRAQLPQDSKRFEGIDSDFRELAYDAQKTPNVVEATNKSGLYEKLEDIQSRLCLCEKALAEYLDTKRLSFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMQFQLDASQNPTKTSLGMYSKEEEYVAFSEACDCSGQVEIWLNRVLRHMKATVRHEMTEGVTAYEEKPRDQWLFDYPAQVALTCTQIWWTTEVGIAFARLEEGYESAMKDYYKKQVAQLKTLITMLIGPLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDEAKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGIMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQRFSFLGEEISLDPSVGIFITMNPGYAGRTELPENLKALFRPCAMVVPDFELISEIMLVAEGFIEARLLARKFITLYRLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPVFMGLIGDLFPALDVPRKRDLDFEAVVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMRRRPVWTDLNPKAVTNDELFGIINPATREWKDGLFSSIMRELAIISHDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMRLLFEISHLRTATPATVSRAGILYINPADLGWNPPVSSWIDQREVQTERANLTILFDKYLPTCLDTLRTRFKKIIPVPEQSMIQMLCYLLECLLTKEDIPADCPKEIYELYFVFAAIWAFGSAVIQDQLVDYRAEFSKWWLTEFKTVKFPSQGTVFDYYIDPETKKFEPWAKLIPQFEFDPEMPLQACLVHTSETIRVCYFMERLMQWRRPVMLVGPAGSGKSVLVGAKLSSLNPEEYMVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNRKLIYFIDDMNMPEVDAYGTVQPHTVIRQHLDYGHWYDRNKLSLKEIMNVQYISCMNPTAGSFTINPRLQRHFSVFALCFPGADALSSIYSTILTHHLKFGNFPTTLQKSIPPLINLAVTFHQKIATTFLPTAIKFHYIFNLRDFANIFQGILFSSVECVKSTQDLVKLYLHESSRVYRDKMVEEKDFNLFDKIQTEFLKKNFDDSEEVLKQTQNLNMYCHFANGIGEPKYMPVQSWDLLNQTLVEALESHNEVNAVMDLVLFEDAIRHICHINRILESPRGNALLVGVGGSGKQSLTKLAAFISSMDVFQITLRKGYQIPDFKVDLASLCLKAGVKNLSTVFLMTDAHVADERFLVLINDLLASGEIPDLYSDEEEENIINNVRNEVKSQGLMDSRENCWKFFIERVQRQLKVTLCFSPVGNKLRIRSRKFPAIVNCTAINWFHEWPQEALESVSLRFLQNTKNIEPAVKQSISKFMAFVHISVNKTSQSYLTNEQRYNYTTPKSFLEFIRLYQSLLERNGKELQAKVERLENGLLKLHSTSAQVDDLKAKLATQEVELRHKNEDTDKLIQVVGVETSKVSREKAIADEEEQKVALIMLEVQQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLMAPGGKVPKDRSWKAAKITMAKVDSFLDSLIHFDKENIHENCLKAIRPYLQDPAFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATSDLTTAQEKLAAIKAKITHLNENLAKLTTKFEKATAEKLKCQQEAELTAGTISLANRLVGGLASENIRWAEAVQNFRQQERTLCGDILLTTAFISYLGFFTKKYRKSLMDGTWRPYLSQLKVPIPTTPTLDPLRMLTDDAEVAAWQNEGLPADRMSMENATILINCERWPLMVDPQLQGIKWIKNKYGEELRVTQIGQKGCLQTIERALEAGDVVLIENLEESIDPVLGPLLGREVIKKGRFIKIGDKECEFNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKSDLTKQQNGFKITLKTLEDNLLSRLSSASGNFLGETALVENLEVTKQTAADVEEKVQEAKLTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVEKAAPSESVTERVTNLIDSITFSVYQYTTRGLFECDKLTYLAQLTFQILLVNQEVNAAELDFLLRAPVQTGTPSPMEFLSHQAWGGIKALSSMEEFCNLDRDIEGSAKSWKKFVESECPEKEKFPQEWKNKTALQRLCMMRAMRPDRMTYAMRDFVEEKLGSKYVMGRALDFVTSFEESGPATPMFFILSPGVDPLKDVENQGKKLGYTFNNRNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEELSEESHPDFRVFISAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFKTILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANTKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLEEFIRPEMLEGELSLAPGFPLPGNMDYSGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLEMQPRDSQAGDGAGITREEKVKTFLEEILDRMTDEFNIAELMAKVEERTPYIVVALQECERMNILTREIQRSLRELHLGLQGELTMTSEMENLQNALYLDVVPESWARRAYPSTAGLAAWFLDLLNRIKELESWTGDFLMPSTVWLTGFFNPQSFLTAIMQSMARKNEWPLDQMALQCDVTKKNREEFRSPPREGAYIYGLFMEGACWDTQTGIIAEAKLKDLTPPMPVMFLKAIPADKQDCRSVYACPVYKTCQRGPTYVWTFNLKTKENPSKWVLAGVALLLQI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB13A7H0-1", "uniprot_id": "A0AB13A7H0_DANRE", "id": "A0AB13A7H0-1", "name": "Dynein axonemal heavy chain 17", "aln": "---MEEQEPLITD---------KRLDYLENCVLKALNVKPERWERCVSAEEQRRVIQEFLDQSEHS---TLSVSVNSAGQLVPALGLSAAVKS-----KAVFFVKRGKGALTADKMKTQLFSGDMCYSPLEQFSVLVDKVVEPVLSNLNNQRDFPKVVSQDLMRHIHALQNNVFVTAGQIKGKTHLPVPLGFKQFEQCSQQLDKRFHVVDKSLIHSMETVVIDWSHQVYKVLKKDSSEPLLEGRNPTPHAEIQFWRNRLADLQGIQQQLQSSKVLTLAELLLAVDSSYYPAFAKMIQDVMEAHNESKNITTFLKPLERLIEDLENADFTELKAKIPPLMHTVCLIWANCRYYSKPARVIVLLQEICNLLIQQARSFLNPDDILKGDVLESLLRVQAAVDLLTHFKNTYEDRRANLSHYQKNEDPVKPWDFSPLMVFVGLDHFMKRLRTIETVLLTVMDMMRLEKIEFGGIQGKSLSQIVQRLHEDFLQTYKSFSEKPYDCLDVNNMEFESDFAEFQLTVDDTNRRLGAIFCNAFDDASGLEHSFKVLDMFGRLLEQPLIAAEAQARYPILIKLFDKQLEDCKTIFKKQMQMEETRGYSPVSKNMPAVSGGLKFVQELQERIQTLYNNFRFINHPCMESVDAKEMMQKYDELMRQLKQYSSKLYDIWTSSVAEKSQFNLNKPLISREPRSRLLSVNFSPQLVSVLREVKYLEARQAEIIPDAAAEIYSSRELLWQYVANLELTTGWYNKIISSVLDVEMPLVQGQLTDIDNKLKGAQENLCWISEGIWEYIQDVREAVSDLEQRLRRTKDNVEEMQSLMKSWATPLHDRKEGKKEMLLNLEERSERVERTYSHIRSSGARIHLLLQENLHLFKADPSSPQWKIYVDYVDEMVIDGFFNAIESTLKFFMENTDADAGLEPLFEAQLRLQVPDLVFQPSLELRSSDSLHELVEGLLRDVFKTSTLVPRLAKHSGFPDYQDDMEDMEELVQTRQHVMQRVKRIMMKCCEYRNSLERYAYLYVDDRKEFMRQFLLYGHVLTSQEIEEHAEHGVPESPPTLERFRQQVDSYERLYEELQRMEPVMVFERWMRVDARAFKSALLNTVKKWSLMFKQHLIDHVTNSLSDLEEFIRLTEAGLGQKVEEGDYRGLVEIMGFLMAVKERQSSTDEMFEPLQQTIDLLKTYEQELPDVVYKQLEVLPEKWNNMKKQAVQVKQHVAPLQAAEVANLRRRCAAFDVEQHTFRETFRKKHFFRFDSVNVHEQLDTTHTQIQELESLMAGLTESANLFEVGVPDYRQLKQCRRELPLLKELWDQALAVRSCLEAWQRTPWSQINVDDMETECKRFSKELRLLDKEARAWDVFNGLDGMVKNTLTSLRAVAELQNPAIRPRHWQQLMAATGVQFTMDQDTTLADLLRLNLHHFEEEVRGIVDRAVKEMGMEKVLGELDATWTSMSFEFEAHPRTQVPLLKSSEELIETLEDNQVQLQNLMSSKYISFFLEEVSSWQRKLSVTDSVISIWFEVQRTWCHLESIFIGSDDIRSQLPEDSKRFEGIDGDFRELTLDARQTPNVVEATNKPGLYSKLEDIQSRLALCEKALSEYLDTKRLAFPRFYFISSADLLDILSSGTDPHQVQKHLSKLFDNMAKLQFQAGEDGGLQKTALGMFSKEDEHVPFSHACDCTGQVEVWLNRVMDSMRATVRHEMTEAVAAYEEKPREQWLFDYPAQVALTCTQIWWTTDVGMAFSRLEEGYENAMKEYYKKQVNQLNTLITMLIGQLTPGDRQKVMTICTIDVHARDVVDKIITQKVENSQAFLWLSQLRHRWGDREKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLVMSGAPAGPAGTGKTETTKDLGRALGIMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQRFNFMGEDVCLVPSVGIFITMNPGYAGRTELPENLKALFRPCAMVVPDFELICEIMLVAEGFIEARLLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPGRAEDQVLMRALRDFNVPKIVTDDMPVFMGLIGDLFPALDVPRKRDMDFEKLVRQSVLELKLQAEDNFVLKVVQLEELLAVRHSVFVVGNAGTGKSQVLKSLHRTYQNMQRRAVWSDLNPKAVTNDELFGIINPATREWRDGLFSNIMRELANITHSGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPSMRLLFEISHLRTATPATVSRAGILYINPADLGWNPLVSSWIDSREVQSEKANLTILFDKYLPSCLDTLRVRFKKIIPVPEQSQVQMLCRLLECLLVPEHTPPDSHKDLYELYFVFAAVWAFGGTMFQDQLLDYRLEFSKWWVTEFKSVKFPAQGSVFDYYIDPDSKKFEPWSKMVPKFEMDPEIPLQACLVHTTETIRVRYFLDRLLERRRPLMLVGNAGTGKSVLVGDKLASLDAEKYTIKNVPFNYYTSSAMLQAVLEKPLEKKAGRNYGPPGSKRLVYFIDDMNMPEVDEYGTVQPHTLIRQHMDYSHWYDRSKLQLKEIHNVQYVSCMNPTAGSFTINPRLQRHFCVFALSFPGADALHSIYCSILSQHVRGESFSVSVQKSCSQLVDLALALHQRITTAFLPTAIKFHYIFNLRDLSNIFQGILFCGSECLRTPQDLLKIYLHESSRVYRDKMLEERDFQLFDKLQEDTVKKIYEDVDALLQETRVMNLFCHFSAGVGEPRYLPVPTWSSLAHTLQEALEAHNELNPAMSLVLFEDAMAHICRISRILESPRGNALLVGVGGSGKQSLTRLAAFISSLDVFQITLKKGYSIPDLKSDLGSLYIKAGVKNIGTVLLMTDAQVADEKFLVLVNDLLASGEIPDLFPDDEVENIIGSLRNEVRAQGLMDTRDNCWRFFIERVRRQLKVALCFSPVGNKLRVRSRKFPAIVNCTAIDWFHEWPQEALESVSLRFLQDLEHIQPELKEPVSKFMAYVHVSVNKTSRDYLLNERRYNYTTPKSFLEQIKLYGNLLALKKRDLQSKMERLENGLEKLNSTTAQVDDLKAKLAAQEVELKLKNESADRLIQVVGVETEKVERERAVADQEEQKVACIAEEVMRKQRDCEEDLAKAEPALIAAQEALNTLNKNNLTELKSFGAPVSAVTNVTAAVMVLTAPGGRVPKDRSWKSAKVMMAKVDAFLEALITFKKENIHENCLKAIQPYLQDPEFQPELVASKSNAAAGLCSWVINIVRFYEVYCEVEPKRQALSKANTDLATAQEKLAVIKAKITLLNENLAKLTAKFEKATADKLRCQQEAETTERTIALANRLVGGLSLEKVRWAEAVQVFQQQERTLCGDVLLITAFVSYLGYFTKHYRLQLMDHCWRPYLSQLQVPVTEG--LDPLSMLTDDADRAVWQNEGLPADRMSTENATILSSCERWPLMVDPQLQGVQWIRNRYAERLRIIRIGQRGYLDSIERALSVGEVVLIENLEESVDPVLGPLLGRETIKKGRCIKIGDKECEYNPSFRLILHTKLANPHYQPELQAQCTLVNFTVTRDGLEDQLLAAVVSMERPDLEELKLNLTKQQNGFKITLKTLEDNLLSRLSSASGNFLGDIELVENLETTKCTAAEIERKVKEAKGTETDINDAREHYRPAAARASLLYFIMNDLNKIHPMYQFSLKAFSVVFQKAVQKAEPDESLKQRVCNLIDSITWCVFQYTTRGLFECDKLTYTAQLAFQVLLMNREISPHELDFLLRYPVQPGLISPVDFLSNHSWGGIKALSTMEEFHNLDRDIEGSAKRWKKFSESECPEKEKFPQEWKSKTALQRLCMMRALRPDRMTYAVRDFVEEKLGSAYVTGRSLDFSVSYEESGSATPMFFILSPGVDPLKDVEKHGRKLGYTFDNRNFHNVSLGQGQEVVAEQALDTAAREGHWVILQNIHLVAKWLGSLEKKLEQHAEGSHQDFRVFMSAEPSSSPDGHIIPQGILENAIKITNEPPTGMHANLHKALDNFTQDTLEMCVRENEFKSILFALCYFHAVVAERRKFGPQGWNRVYPFNTGDLTISVNVLYNYLEANSKVPFDDLRYLFGEIMYGGHITDDWDRRLCRAYLQEFIRPEMMEGELMLAPGFRLPTNTDYSGYHQYIDAALPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLEMQPRDGGAGDGAAGARDEKVKAALDEILEKLPEEFNMSELMAKVEERSPYVVVALQECERMNTLTQEIKRSLRELNLGLKGELTMSSDMESLQSALYLDQVPDSWTRRAYPSLCGLAVWFSDLQSRIRELESWSSDFCLPAAVWLAGFFNPQSFLTAIMQAAARRNQWPLDRMSLQCDVTKKSREEFSSAPREGAYIHGLYMEGARWDTQAGVVTDARLKELTPALPVLFIKAVPVDKQDTRSLYQCPVYKTRQRGHTHVWTFSLKTKDNPAKWTLAGVALLLQI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: .* . ** * . * :*. . ****..: * :::* **.:. . .* * .. *. **... :. *.:**:: . ..:: :..**: ***::: *..:*: ***:* :*: ::*:::.:*: :* *:*: :: * ::**:* **:* * :::* . : : . :*** ::::*:.**.**:** ***::**:.*::*.****:.*::**:.* **: * :** : .* :*:** ::*** *** * :** * *:::* ..* **:: :: ***.:*.::* :: **:*.******.*: * .*.*: ************** .:*.*:*:*:.:* ** ::*.. * *:.**: ::*** :* * *::. *: ***.. :*** ** *: ::: :* :* *.:*: .* *:**.*::*::*** **::**:* : *: : . *** :. :**.*..**: *:* :****:*: :*****..:**:**:**: * *:::**:* :.. :* **::*..:*: : *:.:::* * *:*** ****:::**: :.***::*:: :.** * * ::*.:.*.* ***:::: *::*. :**: * :*:****:**. **: *:*.:: :::**.***:***:*:.**:. : : :*::** ::***:: * ****** :.****::. :*:**:***: :* :** :*:.*:*.* * :*** :* :: .:: *****:::*******:*.:**:*.:*:.. *:**:* *.*::: :::*: *. *:.** :** *:**** ** ***:* ** **: :*.::::*** ***.:**:::***:...** *:***** * *:*** ***: ...: ::*:.*: :* .:*****: :.* *.** *::.: :*. * :*:**:.:* ** *:.::.:*:****:****.: *******:**.:*** *.*.*:**.** * :*: *:**** ****: :** **: **::* *.**::*** :*:***:*****:*.**:**::*: **: :*:** ::**:**::*******.*:::*****.**:*****:***:***:******:.*:**** *****:*:** *: *:*:****** **: **:**:*** **: * * *:*: *****:: *: **: * :**.:** ** :::**.****.****:**:***:* ****** * *.:.**: *.* :*.*: *: ***:*::.:* **** *:**.*.**:. * ***:************** ***:*** ****.***:******.**:*:***:*:*******:*.***.***.* **::**:.*.*::*.*.**.**** *.*:***.***********: ***::*******.**:***..*:************ ****** **:***:***:********* **:**: **:: ****::***.***.******.**.******:********:******:**:*******.** *:***:***********::** . . **:***:***:*:*.**..***:****:***:*: *:*********.*:*******:*****:***************:**:**:*******.***:****** **:******** *: *****:************** *:*:***:*:*************.*. ********************************************.**************************:************************************************************* *.*:**::.* ************************:***************.************: *********:**********************************.*.*******:*****:*********:****************:** :** :**:::::******************************.*********:***:*** *:**.**:******************** **:*****.****** *:*.*****:***********************************:*:********************************* *****:.**:*:*:************:******.*******:**** :**:* ******. *. *.*. *::** ******:****.::.****:*** ******:****:****:**::*******::******:*::*:**:***:*********:***** **::**: :**:**** **:******* **:**:.* * :*********:************************.::*:************ ********:****:**.*****.**.**** ****:********************.**.*.******* ***. **::*:: .*..::*** . *::**:::**:*:*:****.***********::********.. **:::. **:::*****.*******:**:**:****:* : :** ::* : :::*: *::***: *:***:*:** :*. * :** **** ***:*..*.*******: *:*:*.************************:*******:*******:***.* *:* **.** :******:.**:*****:****:****:************:.*:* ****..:****::***:*.*:***:***:*::*****:***********:**************.*******:***********: : *:* :*:.:*****:** ***:**:.** **:************ *:** .** : ::*:.* ******* **:**:***********:*****: ***.:*:*********.**.**:*:**:****** * ** :**:************* *** *******.*********:* **:**:****** ** *:********:**: *****.**::** *.************:****** *:**:**:** ******************:*:********.**.:**::******.*****: *********::******:**:****** * **:*********: *::***:*** *:*********:** ***:****:***:** .*:* ********:.*:. **** ** ***: *.************ ****** .**************::**:*:*.* **: :***:* *: **:**..* **********:***********.***** *********:**.*********************.**:**************************:** :*****************.**************: ****** ** ***::*.**:*** **..**:**********************.**************:******::* *.**: :** *******:.*:*** *********** ***:**:**:*:*:.. ******* ***.* **::***:::**.:*.**:**** *********** **** *********:*****.*********:**:********:********** ** **:*** .*:****.*******************.:*:******:*:**************** *** **::****************.:******: :* ** :****:****:.**:***********:****************************** **.***:************************* *****************:****:***:**************************:** *******:**** ***** ** * **.******** *********************************:****. * ***. :*:****: *:***:::.:***:.*********:**:***:*** *** **:**:******.***:*****:*.**.**.***:* **:**:****** .***.** ** .**:***:*:.** :*::***:**************: **:*:****:*:****:***.**** *.*******:**:**** ****:*::::*:**:***.:**:*:**:*.**** **:* ****** *** *:****.****:**:**.**********", "identical_positions": 3029, "similar_positions": 986, "identity": "67.52%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-020930-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P01150-1", "uniprot_id": "TRH_RAT", "id": "P01150-1", "name": "Pro-thyrotropin-releasing hormone", "aln": "MPGPWLLLALALIFTLTGIPESCALPEAAQEEGAVTPDLPGLENVQVRPERR-FLWKDLQRVRGDLGAALDS------WITKRQHPGKREEEEKD-IEAEERGDLGEGGAWRLHKRQHPGRRANQDKYSWADEEDSDWMPRSWLPDFFLDSWFSDVPQVKRQHPGRRSFPWMESDVTKRQHPGRRFIDPELQRSWEEKEGE----GVLMPEKRQHPGKRALGHPCGPQGTCGQTGLLQ-LLGDLSRGQETLVK-QSP-QVEPWDKEPLEE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62361-1", "uniprot_id": "TRH_MOUSE", "id": "Q62361-1", "name": "Pro-thyrotropin-releasing hormone", "aln": "MQGPWLMMALALIFVLTGIPKSCALLEAAQEEGAVTPDLPGLEKVQVRPERR-FLRKDLQRVRGDLGAALDS------WITKRQHPGKREEKEED-VEAEERGDLGEVGAWRPHKRQHPGRRANQDKDSWSDEGDSDWLPPSWLPDFFLDSWFSDAPQVKRQHPGRRSFPWMESDVTKRQHPGRRFIDPELQRSWEETEGEE---GGLMPEKRQHPGKRAVGHPCGPQGICGQTGLLQ-LLGDLSRGQETLAK-QTP-QLEAWVREPLEE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20396-1", "uniprot_id": "TRH_HUMAN", "id": "P20396-1", "name": "Pro-thyrotropin-releasing hormone", "aln": "MPGPWLLLALALTLNLTGVPGGRAQPEAAQQEAVTAAEHPGLDDFLRQVERLLFLRENIQRLQGDQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEE---EGGAVGPHKRQHPGRREDE------------------------ASWSVDVTQHKRQHPGRRS-PWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPEKRQHPGKRALGGPCGPQGAYGQAGLLLGLLDDLSRSQGAEEKRQHPGRRAAWVREPLEE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5EDF9-1", "uniprot_id": "TRH_DANRE", "id": "Q5EDF9-1", "name": "Pro-thyrotropin-releasing hormone", "aln": "-------MRAVCVFVLACVAVSGAPGVRGQDGPAEEELFQRAEDLLLRSILTQMEEQNSENDQPE-------------WMEKRQHPGKRQHPGKR------EEDLEPEVEMERWRRQHPGKRAPLDLG-------------------MLEDPTALSELSKRQHPGKRYLMLLH----KRQHPGR--------RELQEADGDS-----AELEKRQHPGKRRCEG--WADAGCGLLELLD--------TSGAPEKRQHPGRRAELEDELPGLE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : *: :. . * .*: . :.. : : :: :. : : *: ********:. : . :*****:* . ******:* : ******* *. :* : : ********* .:. * ** . : * * * : * ", "identical_positions": 50, "similar_positions": 41, "identity": "18.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021003-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P80203-1", "uniprot_id": "ACVL1_RAT", "id": "P80203-1", "name": "Activin receptor type-1-like", "aln": "-----------------------------------MTLGIFR------RVFLMLS--VALGLTKGDLVKPSRGQ----LVNCT--CENP-HCKRPICQGAWCTVVLVREQGRHPQVYRGCGSLNQELCLGRP--------------TEFVNHHCCYRSFCNHN---VSLMLEATQTPSEEPEVDAHLPLILGPVLALLVLVALGTLGLWRVRRRQEKQRGLHSDLGE------SSLILKASEQGDSMLGDFLVSDCTTGSGSGLPFLVQRTVARQVALVECVGKGRYGEVWRGSWHGESVAVKIFSSRDEQSWFRETEIYNTVLLRHDNILGFIASDMTSRNSSTQLWLITHYHEHGSLYDFLQRQTLEPQLALRLAVSAACGLAHLHVEIFGTQGKPAIAHRDLKSRNVLVKSNLQCCIADLGLAVMHSQSSDYLDIGNNPRVGTKRYMAPEVLDEQIRTDCFESYKWTDIWAFGLVLWEIARRTIINGIVEDYRPPFYDMVPNDPSFEDMKKVVCVDQQTPTIPNRLAADPVLSGLAQMMRECWYPNPSARLTALRIKKTLQKLSQNP----EKPKVIH-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61288-1", "uniprot_id": "ACVL1_MOUSE", "id": "Q61288-1", "name": "Activin receptor type-1-like", "aln": "-----------------------------------MTLGSFR------RGLLMLS--VAFGLTRGDLAKPSK------LVNCT--CESP-HCKRPFCQGSWCTVVLVREQGRHPQVYRGCGSLNQELCLGRP--------------TEFLNHHCCYRSFCNHN---VSLMLEATQTPSEEPEVDAHLPLILGPVLALPVLVALGALGLWRVRRRQEKQRDLHSDLGE------SSLILKASEQADSMLGDFLDSDCTTGSGSGLPFLVQRTVARQVALVECVGKGRYGEVWRGSWHGESVAVKIFSSRDEQSWFRETEIYNTVLLRHDNILGFIASDMTSRNSSTQLWLITHYHEHGSLYDFLQRQTLEPQLALRLAVSAACGLAHLHVEIFGTQGKPAIAHRDLKSRNVLVKSNLQCCIADLGLAVMHSQSSDYLDIGNNPRVGTKRYMAPEVLDEHIRTDCFESYKWTDIWAFGLVLWEIARRTIINGIVEDYRPPFYDMVPNDPSFEDMKKVVCVDQQTPTIPNRLAADPVLSGLAQMMRECWYPNPSARLTALRIKKTLQKLSHNP----EKPKVIH-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P37023-1", "uniprot_id": "ACVL1_HUMAN", "id": "P37023-1", "name": "Activin receptor type-1-like", "aln": "-----------------------------------MTLGSPR------KGLLMLL--MAL-VTQGDPVKPSRGP----LVTCT--CESP-HCKGPTCRGAWCTVVLVREEGRHPQEHRGCGNLHRELCRGRP--------------TEFVNHYCCDSHLCNHN---VSLVLEATQPPSEQPGTDGQLALILGPVLALLALVALGVLGLWHVRRRQEKQRGLHSELGE------SSLILKASEQGDSMLGDLLDSDCTTGSGSGLPFLVQRTVARQVALVECVGKGRYGEVWRGLWHGESVAVKIFSSRDEQSWFRETEIYNTVLLRHDNILGFIASDMTSRNSSTQLWLITHYHEHGSLYDFLQRQTLEPHLALRLAVSAACGLAHLHVEIFGTQGKPAIAHRDFKSRNVLVKSNLQCCIADLGLAVMHSQGSDYLDIGNNPRVGTKRYMAPEVLDEQIRTDCFESYKWTDIWAFGLVLWEIARRTIVNGIVEDYRPPFYDVVPNDPSFEDMKKVVCVDQQTPTIPNRLAADPVLSGLAQMMRECWYPNPSARLTALRIKKTLQKISNSP----EKPKVIQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P4Z5-1", "uniprot_id": "A0A8M9P4Z5_DANRE", "id": "A0A8M9P4Z5-1", "name": "receptor protein serine/threonine kinase", "aln": "--------------------------------MRDMKASVML------AVLFVLVYSGSYATTADHLMETSTLKNDESSLQCS--CENTNLCENNSCWGRICFYTSVHER-----VVRGC-FQTAEQCYVPA--------------IPGVYTKCCYTHHCNAN---LTMPEKPVCLFSVEKPIR--VILLVGVPLLVLLVIAMAACGLVLWLR---TRRQYCHPVEH------DTSMLKVPSGGDPTYGDIFDEFCTSGSGTGLPYLVQRTMARQISLVECVGKGRYGEVWRGTWMGESVAVKIFSSRDEQSWFRETEIYNTVQLRHENILGFIASDMTSKNSSTQLWLVTHFHELGSLYDFLQYSTLDPEGCLRMCLSIASGLVHLHTEILSTQGKPAIAHRDLKSRNILVKRNGQCCIADLGLAVIHSQSTDYLDVGTNPRVGTKRYMAPEVLDETIRVDVFESYKQTDIWALGLVLWEITRRTIVNGIVEEYRPPFFDMVPSDPSFEEMKKVVCVDQHRPSLHNRLHSHPILSAIAKIMKECWFQSPSARLTALRVRKSLSKLDQDHDYDIDKLKLDL-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K7J3-1", "uniprot_id": "A0A0B4K7J3_DROME", "id": "A0A0B4K7J3-1", "name": "receptor protein serine/threonine kinase", "aln": "MESNIYLVFLLTFLLYNNARAEISDHLREDIPDLDMELSSASSAHLNGKELPAVPQNSVQTHPRRHIKSKRRMKRRYKCYSCEPPCRDPYEFTHTCQNAIQCWKSRTRDADGQVQESRGCSTSPDQLPMICSQNSLKINGPSKRNTGKFVNVVCCAGDYCNEGDFPELLPFDSNDVTVITADTSSISKMLVAVLGPFLVIALLGAVTIFFIRRSHRKRLAASRTKQDPEAYLVNDELLRATSAGDSTLREYLQHSVTSGSGSGLPLLVQRTLAKQVTLIECIGRGKYGEVWRGHWHGESIAVKIFFSRDEESWKRETEIYSTILLRHENILGFIGSDMTSRNSCTQLWLMTHYYPLGSLFDHLNRNALSHNDMVWICLSIANGLVHLHTEIFGKQGKPAMAHRDLKSKNILVTSNGSCVIADFGLAVTHSHVTGQLDLGNNPKVGTKRYMAPEVLDESIDLECFEALRRTDIYAFGLVLWEVCRRTISCGIAEEYKVPFYDVVPMDPSFEDMRKVVCIDNYRPSIPNRWSSDSLMTGMSKLMKECWHQNPDVRLPALRIKKTIHKLASAD----EKIRLDFDEVCV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : : . . . * *... . * .:: *** : . : ** ** . : .. :::. . : :.. : * .: . . :*:... .*. : : *:***:*** *****:*:*::*:**:*:*:******* * ***:***** ****:** ******.*: ***:******.*****:**.*****:**:: ***:*.*: .:*. . : :.:* * **.***.**:..*****:****:**:*:**. * .* ***:**** **: :. **:*.**:************** * : **: : ***:*:******: **** **.*:*: **:*:** *****:*:****:*: *:: ** :..:::.::::*:***. .*..**.***::*:: *: :* :: ", "identical_positions": 197, "similar_positions": 135, "identity": "33.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021007-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P47811-1", "uniprot_id": "MK14_MOUSE", "id": "P47811-1", "name": "Mitogen-activated protein kinase 14", "aln": "MSQ-ERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTP---ARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADP-YDQSFESRDLLIDEWKSLTYDEVISFVPP-----------------------PLDQEEMES---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P70618-1", "uniprot_id": "MK14_RAT", "id": "P70618-1", "name": "Mitogen-activated protein kinase 14", "aln": "MSQ-ERPTFYRQELNKTVWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTP---ARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVAEP-YDQSFESRDFLIDEWKSLTYDEVISFVPP-----------------------PLDQEEMES---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16539-1", "uniprot_id": "MK14_HUMAN", "id": "Q16539-1", "name": "Mitogen-activated protein kinase 14", "aln": "MSQ-ERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTP---ARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADP-YDQSFESRDLLIDEWKSLTYDEVISFVPP-----------------------PLDQEEMES---------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DGE1-1", "uniprot_id": "MK14B_DANRE", "id": "Q9DGE1-1", "name": "Mitogen-activated protein kinase 14B", "aln": "MSQKARPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVMSAFDGKAGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFSP---ATSLEGFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRALKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARLTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPASLISRMPSHEARNYISSLPHMPKRNFADVFIGANPLAVDLLEKMLVLDTDKRITASQALAHPYFAQYHDPDDEPEADP-YDQSFESRDLEIEEWKSKIYIQNRN---------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O61443-1", "uniprot_id": "MK38B_DROME", "id": "O61443-1", "name": "Mitogen-activated protein kinase p38b", "aln": "MSR-KMAKFYKLDINRTEWEIPETYQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQKLSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPAESEMTGYVATRWYRAPEIMLNWMHYNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTPADEFMSRISSESARNYIRSLPVMPRRNFRDIFRGANPLAIDLLEKMLELDADKRITAEQALAHPYMEKYHDPTDEQTAAL-YDQSFEENELPVEKWREMVFSEVTAFKPT-----------------------AAFAELLPKEQ-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32485-1", "uniprot_id": "HOG1_YEAST", "id": "P32485-1", "name": "Mitogen-activated protein kinase HOG1", "aln": "MTT--NEEFIRTQIFGTVFEITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLS--------PLEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENTLKFVTSLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADALAHPYSAPYHDPTDEPVADAKFDWHFNDADLPVDTWRVMMYSEILDFHKIGGSDGQIDISATFDDQVAAATAAAAQAQAQAQAQVQLNMAAHSHNGAGTTGNDHSDIAGGNKVSDHVAANDTITDYGNQAIQYANEFQQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * : :: * :*:.: *::*.*** **:* * * :. **:**: :**.: : ********:****: ***:* * *:* . ::::*:**.* .:**:.::: : * .:.**:::*****.***:***.:*********: :**:*:*:* ****** : :*****:**:********.* :*: .****.***:**:: *:.****.**:.*:. * : *:* ..:. : *..: ::: **. * : * .:* *:******* :*..***** :****.* **** ** * :* *:. :: :: *: : : ", "identical_positions": 151, "similar_positions": 106, "identity": "33.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021008-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GMI6-1", "uniprot_id": "A0A8I6GMI6_RAT", "id": "A0A8I6GMI6-1", "name": "", "aln": "----------------------------------------------------------MVSLLPPHSDVTLPGSTRLEGEPQ--------GDLMQAPGLPGSPAP---------------------------------QNKHANFSCSSFVPDGPPERAPSLPPHSPSV----------ASPGPEQIQSHCTAGPGPGSFRLSPSDKYPGFGFEEGPAGSPGRFLRGNHMPFHPYKGHFHEDIFSEAQTAMALDGHSFKTQGALEAFEEIPVDVGDAEAFLPSFPAEAWCNGLPYPSQEHNQVLQ-------GSEVKVKPQALDNGPGMYCYQPPLQHVYCSSQPTFHQYSP--GGGSYPVPYLGSTHYPYQRIAPQANADG----------------------HQPLFPKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSS-RKGCLWALNPSKIDKMQEELQKWKRKDPIAVRKSMAKPEELDSLIGDKREKLGSPLLGCPPPGLAGPGPIRPLAPSAGLTQPLHPMHPAPGPMPGKNPLQDLLGGHAPSCYGQTYPHLSPSLAPSGHQQPLFSQPDGHLDLQAQPGTPQDSPLPAHTPPSHGAKLLAEPSSARTMHDTLLPDGDLGTDLDAINPSLTDFDFQGNLWEQLKDDSLALDPLVLVTSSPTSSSMLPPPPAAHCFPPGPCLAETGNEAGELAPPGSGGSGALGDMHLSTLYS-AFVELEPTPSSAAASTAVYLSPGSKPMALA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61575-1", "uniprot_id": "FOXN1_MOUSE", "id": "Q61575-1", "name": "Forkhead box protein N1", "aln": "----------------------------------------------------------MVSLLPPQSDVTLPGSTRLEGEPQ--------GDLMQAPGLPDSPAP---------------------------------QNKHANFSCSSFVPDGPPERTPSLPPHSPSI----------ASPDPEQIQGHCTAGPGPGSFRLSPSEKYPGFGFEEGPAGSPGRFLKGNHMPFHPYKRHFHEDIFSEAQTAMALDGHSFKTQGALEAFEEIPVDMGDAEAFLPSFPAEAWCNKLPYPSQEHNQILQ-------GSEVKVKPQALDSGPGMYCYQPPLQHMYCSSQPAFHQYSP--GGGSYPVPYLGSPHYPYQRIAPQANAEG----------------------HQPLFPKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSS-RKGCLWALNPSKIDKMQEELQKWKRKDPIAVRKSMAKPEELDSLIGDKREKLGSPLLGCPPPGLAGPGPIRPMAPSAGLSQPLHPMHPAPGPMPGKNPLQDLLGGHAPSCYGQTYPHLSPSLAPSGHQQPLFPQPDGHLELQAQPGTPQDSPLPAHTPPSHGAKLMAEPSSARTMHDTLLPDGDLGTDLDAINPSLTDFDFQGNLWEQLKDDSLALDPLVLVTSSPTSSSMLPPPPAAHCFPPGPCLAETGNEAGELAPPGSGGSGALGDMHLSTLYS-AFVELESTPSSAAAGPAVYLSPGSKPLALA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15353-1", "uniprot_id": "FOXN1_HUMAN", "id": "O15353-1", "name": "Forkhead box protein N1", "aln": "----------------------------------------------------------MVSLPPPQSDVTLPGPTRLEGERQ--------GDLMQAPGLPGSPAP---------------------------------QSKHAGFSCSSFVSDGPPERTPSLPPHSPRI----------ASPGPEQVQGHCPAGPGPGPFRLSPSDKYPGFGFEEAAASSPGRFLKGSHAPFHPYKRPFHEDVFPEAETTLALKGHSFKTPGPLEAFEEIPVDVAEAEAFLPGFSAEAWCNGLPYPSQEHGPQVL-------GSEVKVKPPVLESGAGMFCYQPPLQHMYCSSQPPFHQYSP--GGGSYPIPYLGSSHYQYQRMAPQASTDG----------------------HQPLFPKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSS-RKGCLWALNPAKIDKMQEELQKWKRKDPIAVRKSMAKPEELDSLIGDKREKLGSPLLGCPPPGLSGSGPIRPLAPPAGLSPPLHSLHPAPGPIPGKNPLQDLLMGHTPSCYGQTYLHLSPGLAPPGPPQPLFPQPDGHLELRAQPGTPQDSPLPAHTPPSHSAKLLAEPSPARTMHDTLLPDGDLGTDLDAINPSLTDFDFQGNLWEQLKDDSLALDPLVLVTSSPTSSSMPPPQPPPHCFPPGPCLTETGSGAGDLAAPGSGGSGALGDLHLTTLYS-AFMELEPTPPTAPAGPSVYLSPSSKPVALA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R9K2-1", "uniprot_id": "F1R9K2_DANRE", "id": "F1R9K2-1", "name": "", "aln": "----------------------------------------------------------MSSEPQGLSFLSISSSSSSPSPSA--------GQLQSFDSL-ESPCF---------------------------------QMPES----QCHQSNG----GEGFVPYSQRK----------SDP-----------------YSQKSAERFRRHSVDGSPVGRDCDLTENSH--YHPYRRQCSEGAISEGQPFSCVR-------RAGLAREIASADGLEEQSSWTTLGTDVETTSIMGTRRPYSEPQE-------SSEEPPG------------YTTVNHQAYSAISPLQHQYYP--SRGIDTV-----SHYYNQSLSTQTSQDSS---------------------PQPLYPKPVYSYSILIFLALRNSKTGSLPVSEIYSFMTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKNGNSS-RKGCLWALNPAKVEKMQEELHKWRRKDPLTVRRSMARPEELERLLGERPEKLKSHFS--LPSSHTHSQPFRVNMHPAYGHQPVHENR-----ILNQKALYNPLTSQNAVLP---PPYISPDPLAFQYYSPATHQPSVGHPSSPRTGS-LDSPLPAHTPPSYSTALQAGHSGTASMQELLL-DGEINNDVDALNPSLTDLQLHGSLWEELRNDSLAPDSLIVMDSASSLAQLSPPP--------------ARDSAGVCAETEDGVQGSISELYLSSFYTTAFTSAENMP-------GLISSSANTAIPLL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XTP7-1", "uniprot_id": "Q9XTP7_DROME", "id": "Q9XTP7-1", "name": "", "aln": "MFELEDYSSGIHEGFFSKYADAAGPSLDFYVSDSMQEMLNVDIRAEIANVVGSSSSDLTSSLDQTLEAISAINNNQSNGNSSQSASYNANANFLTSSGLHASPTAKWMGSSANFWSNSDYYADLGACVNPISVMPLINSTSAGMFSPKKNKTASSTQGRSGAVPSSPSAERDQHKSHLTFSPAQMKVSAGSMRRDQVMAHIPKQISVVTGTGTTAPATMATNSVLQRRNSSAVDAVRKDLVTELRKAQSSPVPNSLEELGKGKGSTLLNASVGATNTIKLAPGIGGLTFANSAAYQKLKQTSLVKSPGGISPGAGSNMGLKREDSNKRGLQASTTPKSIASAANSPHHQMQSNYSLGSPSSLSSSSASSPLGNVSNLVNIANNNTSGAGSGLVKPLQQKVKLPPVGSPFPKPAYSYSCLIALALKNSRAGSLPVSEIYSFLCQHFPYFENAPSGWKNSVRHNLSLNKCFEKIERPATNGNQRKGCRWAMNPDRINKMDEEVQKWSRKDPAAIRGAMVYPQHLESLERGEMKHG------------SADSDVELDSQSEIEESSDLEEHEFEDTMVDAMLVEEEDEEED-------------GDDDEQIINDFDAEDERHANGNQANNLPINHPLLGQKSNDFDIEVGDLYDAIDIEDDKESVRRIISNDQHIIELNPADLNATDGYNQQP----------------------------------------ALKRARVDINYAIGPAGELEQQYGQKVKVQQVIQPQQHP-------PTYNRRKMPLVNRVI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . :: . . . .:: .* ** . . . . . . * * .* . . . . .. . . : : :.:. : ... : . : . . .: . : .: .. ** . . * . . :: .. . . :*** **** ** :**:**::*********.*: :*****:.**.******************:*. ... **** **:** :::**:**::** **** ::* :*. *:.*: * . :: : .. . . : : . : : . . . : . . : ** .:.. ... : . .: :..* . :: . :*:: .. :: : . * * * : : : .. . . : * : ", "identical_positions": 90, "similar_positions": 144, "identity": "11.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021010-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P22909-1", "uniprot_id": "ADA2A_RAT", "id": "P22909-1", "name": "Alpha-2A adrenergic receptor", "aln": "------------------------------------------------------------------MFRQEQPLAEGSFAPMGSLQPDAGNSS-WNGTEAPGGGTRATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKVWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISIEKKGAGGGQQPAEPSCKINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTR-------------------------------------------------VPPSRRGP-----------------------DACSAPPGGADRRPNGLGPERGAGTAGAEAEPLP-----------------------------------------------TQLNG---------APGEPAPTRPRDGDALDLEES-----------------------SSSEHAERPQGPG---------KPERGPRAKGKTKASQVKPGDSLPRRGPGAAGPGASGSGQGEE---------------RAGGAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLIAVG---CPVPYQLFNFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCR-----------------GDRKRIV-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01338-1", "uniprot_id": "ADA2A_MOUSE", "id": "Q01338-1", "name": "Alpha-2A adrenergic receptor", "aln": "------------------------------------------------------------------MFRQEQPLAEGSFAPMGSLQPDAGNSS-WNGTEAPGGGTRATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKVWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISIEKKGAGGGQQPAEPSCKINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTR-------------------------------------------------VPPSRRGP-----------------------DACSAPPGGADRRPNGLGPERGAGPTGAEAEPLP-----------------------------------------------TQLNG---------APGEPAPAGPRDGDALDLEES-----------------------SSSEHAERPPGPR---------RPDRGPRAKGKTRASQVKPGDSLPRRGPGAAGPGASGSGHGEE---------------RGGGAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLIAVG---CPVPSQLFNFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCR-----------------GDRKRIV-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08913-1", "uniprot_id": "ADA2A_HUMAN", "id": "P08913-1", "name": "Alpha-2A adrenergic receptor", "aln": "------------------------------------------------------------------MFRQEQPLAEGSFAPMGSLQPDAGNAS-WNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTR-------------------------------------------------VPPSRRGP-----------------------DAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLP-----------------------------------------------TQLNG---------APGEPAPAGPRDTDALDLEES-----------------------SSSDHAERPPGPR---------RPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEE---------------RVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVG---CSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCR-----------------GDRKRIV-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90WY4-1", "uniprot_id": "ADA2A_DANRE", "id": "Q90WY4-1", "name": "Alpha-2A adrenergic receptor", "aln": "--------------------------------------------------------------------------------------------M-ICGANATNGTNATKEYTLLVALPLSIAVGLLILLIIFGNVLVIIAVFTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMGMWTFGGVWCEIYLALDVLFCTASITHLCAISLDRYWSITQAIEYNLKRTPQRIKRIIFIVWIIAAVISCPPLITMKKSEGD--------ICDINKEKWYIVSSCIGSFFLPCIIMVLVYIRIYQIAKKRTR-------------------------------------------------APPG-------------------------------------DHRKNEVGKK--------ENDPH------------------------------------------------EKLNG---------IQN-AEPDDKDEINGVDMEES-----------------------SSSDHKVSNPCSL---------KKKS---SKGKTKLSQIKPGD-----------------GDKTE---------------ACQTTKASRWKGRQNREKRFTFVLAVVIGVFVICWFPFFFTYTFTAFCD--CCVPETLFKFFFWFGYCNSSLNPIIYTIFNNDFRRSFKKILCR-----------------RDKRRVV-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHD0-1", "uniprot_id": "A0A0B4KHD0_DROME", "id": "A0A0B4KHD0-1", "name": "", "aln": "MDYSRLNANINTGNISTDDFLAVFSTGKPDNATLNPPLLSVDGQLTLPPGSGYVNVNDTIFFLNGSFYNSSLQLAAGFYNQSSASGATSGNLTNPNHTEVHWDGRYPSGYTLTHIVIASIIVTILMIIIVVGNMLVIIAIATEKSLKNIQNWFIASLAVADFFLGLIIMPFSLANELMGYWIFGSWWCDIHSAMDVLLCTASIMNLCLISLDRYWSITKAVDYLKSRTPARAAVMITAVWIMSALICIPPLLGWKVKMPEG----PLPKCELSEDIGYVLYSALGSFYIPSCIMVFVYIRIYFAAKARARRGIKKHPRKTNNEQVTSFTTAKKGTIPMPSSSGVSALQLHQQRQIATIETPPNSASLPMQIPTVTMDLASDISTSEAGELEAVAAQTVLAYANPNGAGTNSVTVVSSGNGGPGASGVPPSSPKETLQVSTIATGRVGLNVPVPPSMGSNSSINVLNNNNGTVAMDGGATAAGGGNGSAVATPGGLQQTGGNELRVSPIAGRCRALSVGVDTDMVSEFDPSSSDSGVVSRCAVVKPLKFRLCQPIFGRKSSNQQRRNEAKAAAKNQQSSGVASKNQQQQQQQQQQQVVKSELEPAIPKTPKPRDPEKEKRRIARKKEKRATLILGLIMGSFIACWLPFFFLYILVPACSSHCNIPESAFAVAFWLGYMNSALNPAIYTIFNKDFRRAFRRILFKXCLAYVCCYRCVYASIEKATERAMGSTPMGYGHGMYQHYRR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. . .. *:* : . :*::: :.**:*****: *.::*: ** *:.*** **:::. :::*******:** * ** **:*: *:***:**:** :** **********:*::* .*** * :* **:::*:*. ***: : . *.:..: *:: *.:***: *. **::**:*** ** *:* .**. . * * : : * ::* . * : .. ::. * ***: . : ...: : .: *.. : .: .: : :::*** *::*.:::* *: **:**** * : . * :* * . **:** **:*** ******:****:*::** : .* : ", "identical_positions": 139, "similar_positions": 121, "identity": "18.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021010-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P19328-1", "uniprot_id": "ADA2B_RAT", "id": "P19328-1", "name": "Alpha-2B adrenergic receptor", "aln": "-------------------------------------------------------------------------------------------MSGP-------TMDHQEPYSVQATAAIASAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFWRAWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQ--RPEPRGLPQCELNQEAWYILASSIGSFFAPCLIMILVYLRIYVIAKRSHCRGLGAKRGSGEGESKKPQ--------------------------------------------------------PVAGGVPTSAKVPTLVSP-LSSVGEANGHPKPPREKEEGETPEDPEAR------------------ALPPTWS-----ALPRSGQGQKKGTSGATAE---EGDEED---------------------------------------------------------------------EEEVEE----CEPQTLPASPASVCNPPLQQPQTSRVLATLRGQVLLGKNVGVASG-QWWRRRTQLSREKRFTFVLAVVIGVFVVCWFPFFFSYSLGAICPQHCKVPHGLFQFFFWIGYCNSSLNPVIYTVFNQDFRRAFRRILCRPWTQTGW----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30545-1", "uniprot_id": "ADA2B_MOUSE", "id": "P30545-1", "name": "Alpha-2B adrenergic receptor", "aln": "-------------------------------------------------------------------------------------------MSGP-------AMVHQEPYSVQATAAIASAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFWRAWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQ--RPEPHGLPQCELNQEAWYILASSIGSFFAPCLIMILVYLRIYVIAKRSHCRGLGAKRGSGEGESKKPH--------------------------------------------------------PAAGGVPASAKVPTLVSP-LSSVGEANGHPKPPREKEEGETPEDPEAR------------------ALPPNWS-----ALPRSVQDQKKGTSGATAE---KGAEED---------------------------------------------------------------------EEEVEE----CEPQTLPASPASVFNPPLQQPQTSRVLATLRGQVLLSKNVGVASG-QWWRRRTQLSREKRFTFVLAVVIGVFVVCWFPFFFSYSLGAICPQHCKVPHGLFQFFFWIGYCNSSLNPVIYTIFNQDFRRAFRRILCRQWTQTGW----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18089-1", "uniprot_id": "ADA2B_HUMAN", "id": "P18089-1", "name": "Alpha-2B adrenergic receptor", "aln": "-------------------------------------------------------------------------------------------------------MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQ--GPQPRGRPQCKLNQEAWYILASSIGSFFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESKQPR--------------------------------------------------------PDHGGALASAKLPALAS--VASAREVNGHSKSTGEKEEGETPEDTGTR------------------ALPPSWA-----ALPNSGQGQKEGVCGASPEDEAEEEEEE---------------------------------------------------------------------EEEEEE----CEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGRGVGAIGG-QWWRRRAQLTREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSSLNPVIYTIFNQDFRRAFRRILCRPWTQTAW----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90WY5-1", "uniprot_id": "ADA2B_DANRE", "id": "Q90WY5-1", "name": "Alpha-2B adrenergic receptor", "aln": "-------------------------------------------------------------------MDSPCPVAVGLPGHTNGTGGTSSPTCNQ-------SMIKLAPYSPEATAAFATAITLMMLITIVGNILVIIAVLTSRSLRGPQNLFLVSLAAADILVATLIIPFSLANELMGYWYFRSVWCEIYLALDVLFCTSSIVHLCAISLDRYMSISRAVTYGPKRTPKRIKCAILVVWLISAVISFPPLLSMNKNKGGGESGALPQCQLNDERWYILYSTIGSFFAPCLIMILVYMRIYQIAKQRTRCPPGEPRKEAPANATTPQHKIQN-----------------------------------------------GRGDETPGTLQKKARPPTLAVSQVESVQQAANTPIANNLLQAPSTTLTPTTP------------------CPSPSPSNSSEVAPSKSKEGKKEKKKKKNNKNKNKKEPDNNNG-------------------------------------------------------------ESMSSDSDTEQGGRGLEVPCTPTMTPSGIHSPATMQKYRDMIATAKGAKLVARKAKQDGTPNSARRKAMVNREKRFTFVLAVVIGVFVICWFPFFFSYSLQAVCPESCALPEPLFKFFFWIGYCNSCLNPVIYTIFNKDFRRAFKKILCKNTKGTFF----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHD0-1", "uniprot_id": "A0A0B4KHD0_DROME", "id": "A0A0B4KHD0-1", "name": "", "aln": "MDYSRLNANINTGNISTDDFLAVFSTGKPDNATLNPPLLSVDGQLTLPPGSGYVNVNDTIFFLNGSFYNSSLQLAAGFYNQSSASGATSGNLTNPNHTEVHWDGRYPSGYTLTHIVIASIIVTILMIIIVVGNMLVIIAIATEKSLKNIQNWFIASLAVADFFLGLIIMPFSLANELMGYWIFGSWWCDIHSAMDVLLCTASIMNLCLISLDRYWSITKAVDYLKSRTPARAAVMITAVWIMSALICIPPLLGWKVK---MPEGPLPKCELSEDIGYVLYSALGSFYIPSCIMVFVYIRIYFAAKARARRGIKKHPRKTNNEQVTSFTTAKKGTIPMPSSSGVSALQLHQQRQIATIETPPNSASLPMQIPTVTMDLASDISTSEAGELEAVAAQTVLAYANPNGAGTNSVTVVSSGNGGPGASGVPPSSPKETLQVSTIATGRVGLNVPVPPSMGSNSSINVLNNNNGTVAMDGGATAAGGGNGSAVATPGGLQQTGGNELRVSPIAGRCRALSVGVDTDMVSEFDPSSSDSGVVSRCAVVKPLKFRLCQPIFGRKSSNQQRRNEAKAAAKNQQSSGVASKNQQQQQQQQQQQVVKSELEPAIPKTPKPRDP-EKEKRRIARKKEKRATLILGLIMGSFIACWLPFFFLYILVPACSSHCNIPESAFAVAFWLGYMNSALNPAIYTIFNKDFRRAFRRILFKXCLAYVCCYRCVYASIEKATERAMGSTPMGYGHGMYQHYRR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . : :*::::: :.** ***:*: *.:**: ** *:.***.**:::. :*:********:*** * **::: *:***:**:**::** ****** ::::*: * .*** * * .**:::*:*.:***: : *:*:*.:: *:* *::***: *. **::**:*** ** : . * * ..*. .. . : . : .*. . .. :. . : ..: .. : : :.. . : : . : :*: .:*** *::*.:::* *: **:**** * * . *.. * :*. * . **:** **.***.***:**:******::** : ", "identical_positions": 129, "similar_positions": 123, "identity": "17.34%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021010-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P22086-1", "uniprot_id": "ADA2C_RAT", "id": "P22086-1", "name": "Alpha-2C adrenergic receptor", "aln": "-------------------------------------------------------------MASPALAAALAAAAAEGPNGSDAGEWGSGGGANASGTDWGPP---PGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSFYRRPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRT-------------------------------------------------------------------------------------------------------LSEKRGPAGPDGASPTTEN-----------------------------------------GLGKAA--GENGHCAPPRT--EVEPDES-SAAERRRRRGALRRGGRRREGAEGDTGSADGPGPG-LAAEQGARTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCR-----------------------------------RKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQLPEPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFR------------------RRRRGFRQ---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01337-1", "uniprot_id": "ADA2C_MOUSE", "id": "Q01337-1", "name": "Alpha-2C adrenergic receptor", "aln": "-------------------------------------------------------------MASPALAAALAAAAAEGPNGSDAGEWGSGGGANASGTDWVPP---PGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSFYRRPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRT-------------------------------------------------------------------------------------------------------LSEKRGPAGPDGASPTTEN-----------------------------------------GLGKAA--GENGHCAPPRT--EVEPDES-SAAERRRRRGALRRGGRRREGAEGDTGSADGPGPG-LAAEQGARTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCR-----------------------------------RKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQLPEPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFR------------------RRRRGFRQ---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18825-1", "uniprot_id": "ADA2C_HUMAN", "id": "P18825-1", "name": "Alpha-2C adrenergic receptor", "aln": "-------------------------------------------------------------MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPP---RGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRT-------------------------------------------------------------------------------------------------------LSEKRAPVGPDGASPTTEN-----------------------------------------GLGAAAGAGENGHCAPPPA--DVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCR-----------------------------------RKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFR------------------RRRRGFRQ---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90WY6-1", "uniprot_id": "ADA2C_DANRE", "id": "Q90WY6-1", "name": "Alpha-2C adrenergic receptor", "aln": "-------------------------------------------------------------MHN------LSYASEED-TYTDTDFTPSGNSTNST------------SYSPATIIGLAGLVSFLILFTIVGNVLVVIAVLTSRALKPPQNLFLVSLASADILVATLIIPFSLANELMGYWFFGEVWCNIYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKGMIVVVWLISAVISFPPLISMDRNTVDERRPMCQLNDHTWYILYSSIGSFFAPCVIMILVYIRIYQVAKTRTRN-------------------------------------------------------------------------------------------------------MSEKRRDPDGGSGTPRLEN-----------------------------------------GLSREDSRRENGHCSSSPG--ERKPAEDNPDADLEDSSSSDEK--AKRSQNETAPSKKD---------RRSSRKNSSSSKHSSRKSRASSKSLDLFSSRRKR-RNTISR-----------------------------------KKISQAREKRFTFVLAVVMGVFVVCWFPFFFSYSLYGICREPCAIPDPLFKFFFWIGYCNSSLNPVIYTIFNQDFRRAFQKILCK------------------SWKRSF-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHD0-1", "uniprot_id": "A0A0B4KHD0_DROME", "id": "A0A0B4KHD0-1", "name": "", "aln": "MDYSRLNANINTGNISTDDFLAVFSTGKPDNATLNPPLLSVDGQLTLPPGSGYVNVNDTIFFLNGSFYNSSLQLAAGFYNQSSASGATSGNLTNPNHTEVHWDGRYPSGYTLTHIVIASIIVTILMIIIVVGNMLVIIAIATEKSLKNIQNWFIASLAVADFFLGLIIMPFSLANELMGYWIFGSWWCDIHSAMDVLLCTASIMNLCLISLDRYWSITKAVDYLKSRTPARAAVMITAVWIMSALICIPPLLGWKVKMPEGPLPKCELSEDIGYVLYSALGSFYIPSCIMVFVYIRIYFAAKARARRGIKKHPRKTNNEQVTSFTTAKKGTIPMPSSSGVSALQLHQQRQIATIETPPNSASLPMQIPTVTMDLASDISTSEAGELEAVAAQTVLAYANPNGAGTNSVTVVSSGNGGPGASGVPPSSPKETLQVSTIATGRVGLNVPVPPSMGSNSSINVLNNNNGTVAMDGGATAAGGGNGSAVATPGGLQQTGGNELRVSPIAGRCRALSVGVDTDMVSEFDPSSSDSGVVSRCAVVKPLKFRLCQPIFGRKSSNQQRRNEAKAAAKNQQSSGVASKNQQQQQQQQQQQVVKSELEPAIPKTPKPRDPEKEKRRIARKKEKRATLILGLIMGSFIACWLPFFFLYILVPACSSHCNIPESAFAVAFWLGYMNSALNPAIYTIFNKDFRRAFRRILFKXCLAYVCCYRCVYASIEKATERAMGSTPMGYGHGMYQHYRR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . :.:. **. :*.. *: : : :* :*::: :***:**:**: *.::*: ** *:.*** **:::. :::*********.** **. **.:: *:***:**:**::** ********:*:**:* .*** *. *..**::**:*.:***:. . * * *.:. *:* *.:***: *. ** :** *** .** *:* :*. . . .. .* : . . ** . .. : :. : : * .. * .. . : *. . :. ::.:: . .: ::::: :*** *::*.::** *: **:**** * * * . * :* . * . **:** **:***.***:**:****:*::** : .*.: ", "identical_positions": 143, "similar_positions": 138, "identity": "19.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021010-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0B4KHD0-1", "uniprot_id": "A0A0B4KHD0_DROME", "id": "A0A0B4KHD0-1", "name": "", "aln": "MDYSRLNANINTGNISTDDFLAVFSTGKPDNATLNPPLLSVDGQLTLPPGSGYVNVNDTIFFLNGSFYNSSLQLAAGFYNQSSASGATSGNLTNPNHTEVHWDGRYPSGYTLTHIVIASIIVTILMIIIVVGNMLVIIAIATEKSLKNIQNWFIASLAVADFFLGLIIMPFSLANELMGYWIFGSWWCDIHSAMDVLLCTASIMNLCLISLDRYWSITKAVDYLKSRTPARAAVMITAVWIMSALICIPPLLGWKVKMPEGPLPKCELSEDIGYVLYSALGSFYIPSCIMVFVYIRIYFAAKARARRGIKKHPRKTNNEQVTSFTTAKKGTIPMPSSSGVSALQLHQQRQIATIETPPNSASLPMQIPTVTMDLASDISTSEAGELEAVAAQTVLAYANPNGAGTNSVTVVSSGNGGPGASGVPPSSPKETLQVSTIATGRVGLNVPVPPSMGSNSSINVLNNNNGTVAMDGGATAAGGGNGSAVATPGGLQQTGGNELRVSPIAGRCRALSVGVDTDMVSEFDPSSSDSGVVSRCAVVKPLKFRLCQPIFGRKSSNQQRRNEAKAAAKNQQSSGVASKNQQQQQQQQQQQVVKSELEPAIPKTPKPRDPEKEKRRIARKKEKRATLILGLIMGSFIACWLPFFFLYILVPACSSHCNIPESAFAVAFWLGYMNSALNPAIYTIFNKDFRRAFRRILFKXCLAYVCCYRCVYASIEKATERAMGSTPMGYGHGMYQHYRR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8JG70-1", "uniprot_id": "AA2DA_DANRE", "id": "Q8JG70-1", "name": "Alpha-2Da adrenergic receptor", "aln": "--------------------------------------------MSVTP--------------------------------TANSTEEAANIT---ASPRLWP------YTEPASAIIILVVSLIILLTIVGNVLVIVAVLTSRALRAPQNLFLVSLACADILVATLVIPFSLANEIMGYWYFGSTWCAFYLALDVLFCTSSIVHLCAISLDRYWSVTKAVRYNLKRTPRRIKCMIAVVWLISAVISFPPLIMTKHDEKE-----CLINDETWYILSSCAVSFFAPGLIMITVYCKIYRVAKQRS----------------STVFVAKNGLERQPSQSETCFVRKDK----FEKESPSSNSSESAQR----QEELDDIDLEES----------------------------------------------------------------------------------------------------------------------------------------------AASDS---------------------RARGSRFSKRRRVEGERRGPQRSCRVSWAAHQEPGSRQQQLAS-------------------KSKVAQMREKRFTFVLAVVMGVFVLCWFPFFFTYSLQAVCGERCGPPEALFKLFFWIGYCNSSVNPIIYTIFNRDFRKAFKKVVCW------------------SAQRT------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::.* :: * :.*:* : * ** . .* ::*:::::: :***:***:*: *.::*: ** *:.*** **:::. :::*******:**** *** ** :: *:***:**:**::** ********:**** * .*** * **:.**::**:*.:***: * . * * :.:: *:* *. **: *. **: ** :** .** *: ::. .**:* **.* .. :: .: *:*...:* . * : .**. .*: ::*** :.*. .:*...:. :. * * .* :*: .:***:.. * ::*: :*** *::*.::** *: **:**** * * ..*..:*. **: * : **:** **::** ******:***:**:::: :::*: ", "identical_positions": 165, "similar_positions": 145, "identity": "22.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021010-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0B4KHD0-1", "uniprot_id": "A0A0B4KHD0_DROME", "id": "A0A0B4KHD0-1", "name": "", "aln": "MDYSRLNANINTGNISTDDFLAVFSTGKPDNATLNPPLLSVDGQLTLPPGSGYVNVNDTIFFLNGSFYNSSLQLAAGFYNQSSASGATSGNLTNPNHTEVHWDGRYPSGYTLTHIVIASIIVTILMIIIVVGNMLVIIAIATEKSLKNIQNWFIASLAVADFFLGLIIMPFSLANELMGYWIFGSWWCDIHSAMDVLLCTASIMNLCLISLDRYWSITKAVDYLKSRTPARAAVMITAVWIMSALICIPPLLGWKVKMPEGPLPKCELSEDIGYVLYSALGSFYIPSCIMVFVYIRIYFAAKARARRGIKKHPRKTNNEQVTSFTTAKKGTIPMPSSSGVSALQLHQQRQIATIETPPNSASLPMQIPTVTMDLASDISTSEAGELEAVAAQTVLAYANPNGAGTNSVTVVSSGNGGPGASGVPPSSPKETLQVSTIATGRVGLNVPVPPSMGSNSSINVLNNNNGTVAMDGGATAAGGGNGSAVATPGGLQQTGGNELRVSPIAGRCRALSVGVDTDMVSEFDPSSSDSGVVSRCAVVKPLKFRLCQPIFGRKSSNQQRRNEAKAAAKNQQSSGVASKNQQQQQQQQQQQVVKSELEPAIPKTPKPRDPEKEKRRIARKKEKRATLILGLIMGSFIACWLPFFFLYILVPACSSHCNIPESAFAVAFWLGYMNSALNPAIYTIFNKDFRRAFRRILFKXCLAYVCCYRCVYASIEKATERAMGSTPMGYGHGMYQHYRR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8JG69-1", "uniprot_id": "AA2DB_DANRE", "id": "Q8JG69-1", "name": "Alpha-2Db adrenergic receptor", "aln": "------------MDLSTITFLLPNSS-EDTNGTSAP---------RLPPHS---------------------QCAS---------------------------------------VLIVLVVTVIILVTIVGNVLVVVAVFTSRALRAPQNLFLVSLAAADILVATLVIPFSLANEVMGYWYLGSTWCAFYLALDVLFCTSSIVHLCAISLDRYWSVTKAVSYNLKRTPRRIKIMITVVWVISAVISFPPLL-----MTKHDELECLLNNETWYILSSCIVSFFAPGLIMILVYCRIYRVAKQRAS----------------TVFVAKNGMERQPSQSETCFVRKGK----SEVESPSSHSSG---------------SRERKGELDDIDLE--------------------------------------------------------------ESSVSNRHRN--------------------------------------------------------SRFAKSRKVEGAQS------------CPKPNGRLSWACSR---------------------------------ASELE----QEPRARQLSLSKSKLAQMREKRFTFVLAVVMGVFVLCWFPFFFTYSLHAICRKSCTIPDSLFNLFFWIGYCNSSVNPIIYTIFNRDFRKAFKKIMCR------------------HSTRT------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::** ** *: : *.* * *** * * *: *: ::**::::: :***:**::*: *.::*: ** *:.***.**:::. :::*******:**** :** ** :: *:***:**:**::** ********:****.* .*** * :***.**::**:*.:**** *.: :* *.:: *:* *.: **: *. **::** *** .** ** :. .**:* **.* .. :: : : :*:*.. :* * .. ***: : : :**:. :.* *.* * . .*. * * ** * .* **** : *:.*: . .* ::*: :*** *::*.::** *: **:**** * * . * . *.**:* * : **:** **::** ******:***:**::*: : : *: ", "identical_positions": 184, "similar_positions": 130, "identity": "24.86%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021011-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI41-1", "uniprot_id": "TRAM1_RAT", "id": "Q5XI41-1", "name": "Translocating chain-associated membrane protein 1", "aln": "MAIR-----KKSNKNPPVLSHEFVLQNHADIVSCLAMLFLLGLMFEITAKGAIIFVALQYNVTRPA-TEEQAAESASLYYYGIKDLATVFFYMLVAIIVHAIIQEYVLDKINRRMHFSKTKHSKFNESGQLSAFYLFACVWGTFILVSENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFPELYFQKTK-KEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFYFSD--EKYQKGFSLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAVLASICITQAFMMWKFINFQLRRWREHSAFQAPPVKRKPAVTK-GRSSRKGTENGVNGTVTSNGADSPRSRKEKSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91V04-1", "uniprot_id": "TRAM1_MOUSE", "id": "Q91V04-1", "name": "Translocating chain-associated membrane protein 1", "aln": "MAIR-----KKSNKNPPLLSHEFLLQNHADIVSCLAMLFLLGLMFEVTAKGAIIFVALQYNVTRPA-TEEQATESASLYHYGIKDLATVLFYMLVAIIIHAIIQEYVLDKINRRMHFSKTKHSKFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQTKFFYISQLAYWLHAFPELYFQKTK-KEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFYFSD--EKYQKGFSLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAVLASICITQAFMMWKFINFQLRRWREHSAFQAPPVKRKPAVTK-GRSSRKGTENGVNGTVTSNGADSPRNRKEKSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15629-1", "uniprot_id": "TRAM1_HUMAN", "id": "Q15629-1", "name": "Translocating chain-associated membrane protein 1", "aln": "MAIR-----KKSTKSPPVLSHEFVLQNHADIVSCVAMVFLLGLMFEITAKASIIFVTLQYNVTLPA-TEEQATESVSLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFPELYFQKTK-KEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFYFSN--EKYQKGFSLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAVLASICVTQAFMMWKFINFQLRRWREHSAFQAPAVKKKPTVTK-GRSSKKGTENGVNGTLTSNVADSPRNKKEKSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P4U7-1", "uniprot_id": "Q6P4U7_DANRE", "id": "Q6P4U7-1", "name": "Translocating chain-associated membrane protein", "aln": "MGIR-----KKTTKNPPVLSHEFVIQNHADIVSCVAMVFLLGLMFEITSKVAVLFITVQYNVTIPA-NGGPEEATVNYFHYGLKDVATIFFYMLVAIIMHAIIQEYVLDKINRKMHFSKTKHSKFNESGQLSAFYLFSCLWGASILVSENILSNPVSLWDGYPHTLMQFQMKFYYICQLGYWLHAIPELYFQKAK-KEDIPRQLVYISLYLVHIAGAYALNLNRLGLVLLVLHYFVELIFHVSRLIYFSN--EERQSGFTVWAVLFVLGRLLTLSLSVLTVGFGLAGAEKQGLNLAEGSFNVLFVRVTVLAAICITQAFMMWKFINFQLRRWREQAQTQT--LKKKSSSSK-SKSKK---ANGVNGSVGASGADSPRARKEKSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8N609-1", "uniprot_id": "TR1L1_HUMAN", "id": "Q8N609-1", "name": "Translocating chain-associated membrane protein 1-like 1", "aln": "MGLR-----KKSTKNPPVLSQEFILQNHADIVSCVGMFFLLGLVFEGTAEASIVFLTLQHSVAVPA-AEEQATGSKSLYYYGVKDLATVFFYMLVAIIIHATIQEYVLDKINKRMQFTKAKQNKFNESGQFSVFYFFSCIWGTFILISENCLSDPTLIWKARPHSMMTFQMKFFYISQLAYWFHAFPELYFQKTK-KQDIPRQLVYIGLHLFHITGAYLLYLNHLGLLLLVLHYFVELLSHMCGLFYFSD--EKYQKGISLWAIVFILGRLVTLIVSVLTVGFHLAGSQNRNPDALTGNVNVLAAKIAVLSSSCTIQAYVTWNLITLWLQRWVEDSNIQASCMKKK----R-SRSSKKRTENGV-GVETSNRVDCPPKRKEKSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8QZR0-1", "uniprot_id": "TR1L1_MOUSE", "id": "Q8QZR0-1", "name": "Translocating chain-associated membrane protein 1-like 1", "aln": "MGLR-----KKNARNPPVLSHEFMVQNHADMVSCVGMFFVLGLMFEGTSEMSIAFLTLQHGVVVP--AEGLPSGSRTLYHYGVKDLATVFFYMLVAIIIHATIQEYVLDKLSRRLQLTKGKQNKLNEAGQLSVFYIVSGIWGMIILASENCLSDPTLLWKSQPHNMMTFQMKFFYISQLAYWFHSFPELYFQKVR-KQDIPGQLIYIGLHLFHIGGAYLLYLNHLGLLLLMLHYAVELLSSVCSLLYFGD--ERYQKGLSLWPIVFISGRLVTLIVSVVTVGLHLAG-TNRNGNALSGNVNVLAAKIAVLSSSCSIQVYITWTLTTVWLQRWLEDANLHV-CGRKR----R-SR-ARKGTEN---GVENPNRIDSPPKKKEKAP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9W5C2-1", "uniprot_id": "Q9W5C2_DROME", "id": "Q9W5C2-1", "name": "Translocating chain-associated membrane protein", "aln": "MAIKPGLGRKTSNKNPPILSHEFVIQNHADIISCVAMVFVVGLMNESTAAFASAFISLHHNVSGEDPSREQPYGKPYTYIAGIKDYCAIFFYTLTCIIMHAIIQEFVLDKISKKLHLSKFKLARFNESGQLVAFYLLSFVWGAHVLLKEGYLGQVAQLWEGFPDHPMSFLHKFYFVVQLAYYLHMLPELYFQKIKTKEEQQPKIVHSISGFTLIVLAYTLSFQRLALVLLTLHYFSELLSHVFQLIGVFDREERLAKLRVVNNAVFFLIRFATSVIGVLTLYYGIGG----------------VRSLLALGGLIALQGYLVFSFITEQLRAKREAKKEAKREAKLALQTKKPAKTPKDKVKRKKESDLPEADQTSPSPIKQKLK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:: *.. :.**:**:**::*****::**:.*.*::**: * *: : *:::::.* . : *:** .:::** *..**:** ***::***:.::::::* * ::**:**: .**:.: :** :* .*. :.: . :* . *. * * **::: **.*::* :******* : *:: :::: : * ** * :::*.*:** *** *:: : *: . : *. . : :*. *: * :.*:*: :. : .*.. * :: :.: . *: * : : .: : . . .* *:* ", "identical_positions": 95, "similar_positions": 124, "identity": "24.74%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021015-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50442-1", "uniprot_id": "GATM_RAT", "id": "P50442-1", "name": "Glycine amidinotransferase, mitochondrial", "aln": "MLRVRCLRGGSRGAEAVHYIGSRLGGSLTGWVQRTFQSTQAATASSQNSCAAEDKATHPLPKDCPVSSYNEWDPLEEVIVGRAENACVPPFTVEVKANTYEKYWPFYQKNGGLYFPKDHLKKAVAEVEEMCNILSMEGVTVKRPDPIDWSLKYKTPDFESTGLYSAMPRDILMVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYDQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPNPMHIDATFNIIGPGLVLSNPDRPCHQIDLFKKAGWTIVTPPTPVIPDDHPLWMSSKWLSMNVLMLDEKRVMVDANEVPIQKMFEKLGISTIKVNIRNANSLGGGFHCWTCDVRRRGTLQSYFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D964-1", "uniprot_id": "GATM_MOUSE", "id": "Q9D964-1", "name": "Glycine amidinotransferase, mitochondrial", "aln": "MLRVRCLRGGSRGAEAVHYIGSRLGGSLTGWVQRTFQSTQAATASSRNSCAAEDKATHPLPKDCPVSSYNEWDPLEEVIVGRAENACVPPFTVEVKANTYEKYWPFYQKNGGLYFPKDHLKKAVAEVEEMCNILSMEGVTVRRPDPIDWSLKYKTPDFESTGLYSAMPRDILMVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYDQNYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPNPMHIDATFNIIGPGLVLSNPDRPCHQIDLFKKAGWTIVTPPTPVIPDDHPLWMSSKWLSMNVLMLDEKRVMVDANEVPIQKMFEKLGISTIKVNIRNANSLGGGFHCWTCDVRRRGTLQSYFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50440-1", "uniprot_id": "GATM_HUMAN", "id": "P50440-1", "name": "Glycine amidinotransferase, mitochondrial", "aln": "MLRVRCLRGGSRGAEAVHYIGSRLGRTLTGWVQRTFQSTQAATASSRNSCAADDKATEPLPKDCPVSSYNEWDPLEEVIVGRAENACVPPFTIEVKANTYEKYWPFYQKQGGHYFPKDHLKKAVAEIEEMCNILKTEGVTVRRPDPIDWSLKYKTPDFESTGLYSAMPRDILIVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYNQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPNPMHIDATFNIIGPGIVLSNPDRPCHQIDLFKKAGWTIITPPTPIIPDDHPLWMSSKWLSMNVLMLDEKRVMVDANEVPIQKMFEKLGITTIKVNIRNANSLGGGFHCWTCDVRRRGTLQSYLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PH19-1", "uniprot_id": "GATM_DANRE", "id": "Q6PH19-1", "name": "Glycine amidinotransferase, mitochondrial", "aln": "MLRVRCLRGGSRGAEAAHLIGALVGRALSGRLSRASRSS-SSSAAAQLPLSAHEQVPEPTAEECPVCAHNEWDPLEEVIVGRAENACVPPFTVEVKANTYEKYWPFYQQYGGQTFPKEHVQKAVAEIEEMCNILQHEGVTVRRPEPVDWSLEYRTPDFSSTGMYAAMPRDILMVVGNEIIEAPMAWRARFFEYRAYRPLIKEYFRRGARWTTAPKPTMADQLYDQDYPIRTVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGTDIFVQRSQVTNYMGIEWMRRHLSPTYKIHIISFKDPNPMHIDATFNIIGPGLVLSNPDRPCRQIEMFKKAGWTVVTPPTPLIPDNHPLWMSSKWLSMNVLMLDEKRVMVDANESTIQKMFESLGIKTVKVSIRHANSLGGGFHCWTTDVRRRGTLQSYFL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************.* **: :* :*:* :.*: :*: :::*::: . :*.::...* .::***.::***********************:***************: ** ***:*::*****:*******. *****:**:*:****:*:****.***:*:*******:**************:*********.:**:**:***:***********:**:*:***::******************************* ***.********:*********:* *::***********************:*********:**::*******::*****:***:**************************** .******.***.*:**.**:************ ***********: ", "identical_positions": 328, "similar_positions": 77, "identity": "77.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021016-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61619-1", "uniprot_id": "S61A1_HUMAN", "id": "P61619-1", "name": "Protein transport protein Sec61 subunit alpha isoform 1", "aln": "-MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAIT--LFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRG--MEFEGAIIALFHLLATRTDKVR-ALREAFYRQNLPNLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLG-TWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKE---------QSEVGSMGALLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61621-1", "uniprot_id": "S61A1_RAT", "id": "P61621-1", "name": "Protein transport protein Sec61 subunit alpha isoform 1", "aln": "-MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAIT--LFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRG--MEFEGAIIALFHLLATRTDKVR-ALREAFYRQNLPNLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLG-TWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKE---------QSEVGSMGALLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61620-1", "uniprot_id": "S61A1_MOUSE", "id": "P61620-1", "name": "Protein transport protein Sec61 subunit alpha isoform 1", "aln": "-MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAIT--LFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRG--MEFEGAIIALFHLLATRTDKVR-ALREAFYRQNLPNLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLG-TWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKE---------QSEVGSMGALLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q90YL4-1", "uniprot_id": "S61A2_DANRE", "id": "Q90YL4-1", "name": "Protein transport protein Sec61 subunit alpha-like 2", "aln": "-MAIKFLEVIKPFCAVLPEIQKPERRIQFKEKVLWTAIT--LFIFLVCCQIPLFGIMSSDSADPFYWMRVIMASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLFGMIITIGQAVVYVMTGMYGDPSEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRG--TEFEGAIIALFHLLATRTDKVR-ALREAFYRQNLPNLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLG-TWSDTSTGGPARAYPVGGLCYYLSPPESFGTVLEDPIHAIIYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEIFVKE---------QSEVGSVGALLF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32915-1", "uniprot_id": "SC61A_YEAST", "id": "P32915-1", "name": "Protein transport protein SEC61", "aln": "MSSNRVLDLFKPFESFLPEVIAPERKVPYNQKLIWTGVS--LLIFLILGQIPLYGIVSSETSDPLYWLRAMLASNRGTLLELGVSPIITSSMIFQFLQGTQLLQIRPESKQDRELFQIAQKVCAIILILGQALVVVMTGNYGAPSDLGLPICLLLIFQLMFASLIVMLLDELLSKGYGLGSGISLFTATNIAEQIFWRAFAPTTVNSGRG--KEFEGAVIAFFHLLAVRKDKKR-ALVEAFYRTNLPNMFQVLMTVAIFLFVLYLQGFRYELPIRSTKVRGQIGIYPIKLFYTSNTPIMLQSALTSNIFLISQILFQKYPTNPLIRLIG-VWG-IRPGTQGPQMALSGLAYYIQPLMSLSEALLDPIKTIVYITFVLGSCAVFSKTWIEISGTSPRDIAKQFKDQGMVINGKRETSIYRELKKIIPTAAAFGGATIGALSVGSDLLGTLGSGASILMATTTIYGYYEAAAKEGGFT-----KNLVPGFSDLM-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38353-1", "uniprot_id": "SSH1_YEAST", "id": "P38353-1", "name": "Sec sixty-one protein homolog", "aln": "MSGFRLIDIVKPILPILPEVELPFEKLPFDDKIVYTIFAGLIYLFAQFPLVGLPKATTPNVNDPIYFLRGVFGCEPRTLLEFGLFPNISSGLILQLLAGLKVIKVNFKIQSDRELFQSLTKVFAIVQYVILTNIFIFAGYFG--DDLSVVQIGLINFQLVGAGIFTTLLAEVIDKGFGFSSGAMIINTVVIATNLVADTFGVSQIKVGEDDQTEAQGALINLIQGLRSKHKTFIGGIISAFNRDYLPNLTTTIIVLAIAIIVCYLQSVRVELPIRSTRARGTNNVYPIKLLYTGCLSVLFSYTILFYIHIFAFVLIQLVAKNEPTHIICKIMGHYENANNLLAVPTFPLSLLAPPTSFFKGVTQQPLTFITYSAFILVTGIWFADKWQAISGSSARDVALEFKDQGITLMGRREQNVAKELNKVIPIAAVTGASVLSLITVIGESLGLKGKAAGIVVGIAGGFSLLEVITIEYQQSGGQSALNQVLGVPGAM-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.:::.**: .***: * .:: :.:*:::* .: : :* : * :.: **:*::* ::..: **:*:*: * ::*.:*:*:* * ::::: . .** **: *: .:: : : : :::* :* .::. *: :**. *.::. ** *::.**:*:.** :: :. *. :. :*. : :: *.. * :**:* ::: * : .. .: .** * ***: : .: : .* *:*..* :***:*:: ** . *****:**. .:::. :: :.::: :* . * :: . . . *. * : . :*: : * *:* : *:..* :**:*.:*:* ::*:* :.: *:** .: :**:: ** **. *. :. ::* .: ** *..:.*::. : : * . * . * .. : ", "identical_positions": 109, "similar_positions": 190, "identity": "22.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021021-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V6M6-1", "uniprot_id": "G3V6M6_RAT", "id": "G3V6M6-1", "name": "", "aln": "----------MTQSLSGPRTLGKVSVRLEAPGAPWPRRNGDPAASPPSPAQPFRPPRMEAPASAQTPHP--HEPISFGIDQILNSPDQDS--------APAPRGPDGAS---YLGGPPGGRPGAAYPSLPASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLMLQLQHDAFQKSLNDSIQP--DPLCLHNSSLFALQNLQPWE-EDSSKVPAVTSLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55144-1", "uniprot_id": "TLX3_MOUSE", "id": "O55144-1", "name": "T-cell leukemia homeobox protein 3", "aln": "---------------------------------------------------------MEAPASAQTPHP--HEPISFGIDQILNSPDQDS--------APAPRGPDGAS---YLGGPPGGRPGAAYPSLPASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLMLQLQHDAFQKSLNDSIQP--DPLCLHNSSLFALQNLQPWE-EDSSKVPAVTSLV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43711-1", "uniprot_id": "TLX3_HUMAN", "id": "O43711-1", "name": "T-cell leukemia homeobox protein 3", "aln": "---------------------------------------------------------MEAPASAQTPHP--HEPISFGIDQILNSPDQDS--------APAPRGPDGAS---YLGGPPGGRPGATYPSLPASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLMLQLQHDAFQKSLNDSIQP--DPLCLHNSSLFALQNLQPWE-EDSSKVPAVTSLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PA75-1", "uniprot_id": "A0A8M1PA75_DANRE", "id": "A0A8M1PA75-1", "name": "", "aln": "---------------------------------------------------MDRAPSSSPSGTSQTSQPTQHEPISFGIDQILSGTDQESQQNSTRNSSESSSGSSSASGGCYHLGSPTGASATPYTTLTGTFHGIAAPYEESSPYGMNLTLAPGGVIRVPAHRPLAAAVPPPMASAVPG---------LGSLSFPWMESSQRFAKDRF--AAALTPFTVARRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKTLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRLMIQLQHDAFQKSLTDSVPT--DPLCIHNSSLFALQNLQPWASEESSKLGGVTALV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KS72-1", "uniprot_id": "Q7KS72_DROME", "id": "Q7KS72-1", "name": "", "aln": "MSSHEEDDHEHENEHGEEVEEQEIHVDVDSDSRMSCGSGSDVDMDGGSCYDESETPLSESLQSEQTRSSS-SENLPFSISRLLSKPFETS----------HHHHNNNNH---LLSSSPGSSSNNNNSGEKGEEKELLQQEDHDLAYKLATSIANSTYGSAAALYSYPHLYPSAAGGHVLRVPPQRTPLTWALPPLHHAALAHQAVKDRL--AAAFP---IARRIGHPYQNRTPPKRKKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQAANRLMLSLQAEAISKGFAPPSAPLGSQGGVNGAPLAALHGLQPWA--EASHAAGC----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : ** . * :.*.*.::*. . : * .. ..* . . . . : :. .* : ::* . ..* . . *.. . : . : ::: .***: ***:. ::**********************:*:*:.*******:*************: ******************************** *.***:.** :*:.*.: . . . ::.:.* **:.**** ::*: . ", "identical_positions": 110, "similar_positions": 76, "identity": "30.22%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021025-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LW16-1", "uniprot_id": "F1LW16_RAT", "id": "F1LW16-1", "name": "", "aln": "MGYQACPVFLLILDRLFILLDTGTTPVTRKAAAQQLGEVVKLHPHELNNLLSKVLIYLRSANWDTRIAAGQAVEAIVKNVPEWNPVPRTK-----------------QEPT-ECSMEDSSTTDR--LNFDRFDICRLLQHGASLLGSAGAEFEVQDEK----SGEVDP--KERIARQRKLLQKK--LGLNMGEAIGMSTEELFNDEDLDYTPTSAALVNK----------QSTLQAAELIDSEFRAG------MSNRQKNKAKRMAKLFAK---------------QRSRDAVETNEKSNDSTDGEPEEKRRKV-ANVVINQTASDAKVLIDNVPE---SSSFIEETNEWPLESFCEELCNDLFNPSWEVRHGAGTGLREILKAHGKSGGKMGDSTLEEMIQQHQEWLEDLVIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVVLKHMNETGVHKTVDVLLKLLT---------QEQWEVRHGGLLGIKYALAVRQDVINTL--LPKVLTRIIEGLQDLDDDVRAVAAASLVPVVESLVYLQ-TQKVPSIINTLWDSLLELDD-LTASTNSIMTLLSSMLTYPQVQQCSIQQSLT--------VLVPRVWPFLHHTISSVRRAALETLFTLLSTQ-------DQN----------------SSSWLIPILSDMLRHIFQFCVLESSQEILDLIHKVWMELLSKASVQYVVAAACPWMGAWLCLMMQPSHLPID---LNMLLEVK---------ARTKEKTGGKVRQG--QMQSKEVLQEYIAGADTIMEDPATRDFVVMR--ARMMAAKLLGALCCCICDPG--VNMVNQEIKPAESLGQLLLFHLNSKSALQRISAALVICEWAALQKECKAVTLAVQPRLLDILSEHLY-------YDEIAVPFTRMQNECKQFISSLADA-----------HIEVGNRVNN--NVLTIDQANDLVTTLFNEVTSTFD--LNPQVLQQLDSKRHQVQMTVAETNQEWQVLQLRVHTFAACAVVSLQQLPEKLNPIIKPLMETIKKEENTLVQNYAAQYIAKLLQQCTTRTPCPNS-KVIKNLCSSLCVDPYLTPCVTCPVPTQSG--QENSKGSNSEKDGMHHTVTKHRGIITLYRH----QKAAFAITSRRGP-IPKAIKAQIA-DLPAGSSGNILVELDEGQKPYLVQRRGAEFALTTVVKHFGAEMALKLPHLWDAMVGPLKTMIDLNNFDGKSLLERGDAPAQELVNSLQVFETAAASMDSELHP-LLVQHLPHLYMCLQYPSTAVRHMAARCVGVMSKIATMETMNIFLEKVLPWLGAIDDNVKQEGAIEALACVMEQLDVGIVPYIVLLVVPVLGRMSDQTDSVRFMATQCFATLIRLMPLEAGIPDPPNMSEELIQLKAKERHFLEQLLDGKKLENYKIPVPINAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHCQRAQEYARSKLAECMPLPSLVVCPPTLTGHWVDEVGKFCSR-EYLNPLHYTGPPTERIRLQHQV-KRHNLIVASYDVVRNDIDFFRNIKFNYCILDEGHVIKNGKTKLSKAVKQLTANYRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGVLAMDALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCTLSPLQVQLYEDFAKSRAKCDVDETVSSAALSEETEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEFKNTTEKLAVQNSSLHDIQHAPKLSALKQLLLDCGLG-------NGTSSESGTESVVAQHRILIFCQLKSMLDIVEHDLLKPHLPSVTYLRLDGSIPPGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMNIANTVISQENSSLQSMGTDQLLDLFTLD------------KDGKAEKAD----SSTSGKASMKSVLENLSDLWDAEQYDSEYNLETFMRSLE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9QAE3-1", "uniprot_id": "E9QAE3_MOUSE", "id": "E9QAE3-1", "name": "", "aln": "-------MAVSRLDRLFILLDTGTTPVTRKAAAQQLGEVVKLHPHELNNLLSKVLIYLRSTNWDTRIAAGQAVEAIVKNVPEWNPVPRTK-----------------QEPT-ESSMEDSSTTDR--LNFDRFDICRLLQHGASLLGSAGAEFEVQDEK----SGEVDP--KERIARQRKLLQKK--LGLNMGEAIGMSTEELFNDEDLDYTPTSAALVNK----------QSTLQAAELIDSEFRAG------MSNRQKNKAKRMAKLFAK---------------QRSRDAVETNEKSNDSTDGEPEEKRRKV-ANVVINQTASDSKVLIDNVPE---SSSLIEETNEWPLESFCEELCNDLFNPSWEVRHGAGTGLREILKAHGKSGGKMGDSTLEEMIQQHQEWLEDLVIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVVLKHMNETGVHKTVDVLLKLLT---------QEQWEVRHGGLLGIKYALAVRQDVINTL--LPKVLTRIIEGLQDLDDDVRAVAAASLVPVVESLVYLQ-TQKVPSIINTLWDSLLELDD-LTASTNSIMTLLSSMLTYPQVQQCSIQQSLT--------VLVPRVWPFLHHTISSVRRAALETLFTLLSTQ-------DEN----------------SSSWLIPILSDMLRHIFQFCVLESSQEILDLIHKVWMELLSKASVQYLVAAACPWMSAWLCLMMQPSHLPID---LNMLLEVK---------ARAKEKTGGKVRQG--QIQNKEVLQEYIAGADTIMEDPATRDFVVMR--ARMMAAKLLGALCCYICDPS--VNMVNQEIKPADSLGQLLLFYLNSKSALQRISVALVICEWAALQKECKAVTLAVQPRLLDILSEHLY-------YDEIAVPFTRMQNECKQFISSLADA-----------HIEVGNRVNN--NVLTIDQANDLVTTIFNEVTSTFD--LNPQVLQQLDSKRHQVQMTVAETNQEWQVLQLRVHTFAACAVVSLQQLPEKLNPIIKPLMETIKKEENTLVQNYAAQYIAKLLQQCTTRTPCPNS-KVIKNLCSSLCVDPYLTPCVTCPVPTQSG--QENSKGSNSEKDGMHHTVTKHRGIITLYRH----QKAAFAITSRRGP-IPKAIKAQIA-DLPAGSSGTILVELDEGQKPYLVQRRGAEFALTTIVKHFGAEMAVKLPHLWDAMVGPLKSMIDLNNFDGKSLLERGDVPAQELVNSLQVFEIAAASMDSALHP-LLVQHLPHLYMCLQYPSTAVRHMAARCIGVMSKIATMETMNIFLEKVLPWLGAIDDNVKQEGAIEALACVMEQLDVGIVPYIVLLVVPVLGRMSDQTDSVRFMATQCFATLIRLMPLEAGIPDPPNMSEELIQLKAKERHFLEQLLDGKKLENYKIPVPINAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHCQRAQEYARSKLAECMPLPSLVVCPPTLTGHWVDEVGKFCSR-EYLNPLHYTGPPTERIRLQHQV-KRHNLIVASYDVVRNDIDFFRNIKFNYCILDEGHVIKNGKTKLSKAVKQLTANYRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGVLAMDALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCTLSPLQVQLYEDFAKSRAKCDVDETVSSAALSEETEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEFKSTTEKLTVQNSSLHDIQHAPKLSALKQLLLDCGLG-------NGSSTESGTESVVAQHRILIFCQLKSMLDIVEHDLLKPHLPSVTYLRLDGSIPPGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMNIANTVISQENSSLQSMGTDQLLDLFTLD------------KDGKAEKAD----SSTSGKASMKSVLENLSDLWDAEQYDSEYNLETFMRSLE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14981-1", "uniprot_id": "BTAF1_HUMAN", "id": "O14981-1", "name": "TATA-binding protein-associated factor 172", "aln": "-------MAVSRLDRLFILLDTGTTPVTRKAAAQQLGEVVKLHPHELNNLLSKVLIYLRSANWDTRIAAGQAVEAIVKNVPEWNPVPRTR-----------------QEPTSESSMEDSPTTER--LNFDRFDICRLLQHGASLLGSAGAEFEVQDEK----SGEVDP--KERIARQRKLLQKK--LGLNMGEAIGMSTEELFNDEDLDYTPTSASFVNK----------QPTLQAAELIDSEFRAG------MSNRQKNKAKRMAKLFAK---------------QRSRDAVETNEKSNDSTDGEPEEKRRKI-ANVVINQSANDSKVLIDNIPD---SSSLIEETNEWPLESFCEELCNDLFNPSWEVRHGAGTGLREILKAHGKSGGKMGDSTLEEMIQQHQEWLEDLVIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVVLKHMNETGVHKTVDVLLKLLT---------QEQWEVRHGGLLGIKYALAVRQDVINTL--LPKVLTRIIEGLQDLDDDVRAVAAASLVPVVESLVYLQ-TQKVPFIINTLWDALLELDD-LTASTNSIMTLLSSLLTYPQVQQCSIQQSLT--------VLVPRVWPFLHHTISSVRRAALETLFTLLSTQ-------DQN----------------SSSWLIPILPDMLRHIFQFCVLESSQEILDLIHKVWMELLSKASVQYVVAAACPWMGAWLCLMMQPSHLPID---LNMLLEVK---------ARAKEKTGGKVRQG--QSQNKEVLQEYIAGADTIMEDPATRDFVVMR--ARMMAAKLLGALCCCICDPG--VNVVTQEIKPAESLGQLLLFHLNSKSALQRISVALVICEWAALQKECKAVTLAVQPRLLDILSEHLY-------YDEIAVPFTRMQNECKQLISSLADV-----------HIEVGNRVNN--NVLTIDQASDLVTTVFNEATSSFD--LNPQVLQQLDSKRQQVQMTVTETNQEWQVLQLRVHTFAACAVVSLQQLPEKLNPIIKPLMETIKKEENTLVQNYAAQCIAKLLQQCTTRTPCPNS-KIIKNLCSSLCVDPYLTPCVTCPVPTQSG--QENSKGSTSEKDGMHHTVTKHRGIITLYRH----QKAAFAITSRRGP-TPKAVKAQIA-DLPAGSSGNILVELDEAQKPYLVQRRGAEFALTTIVKHFGGEMAVKLPHLWDAMVGPLRNTIDINNFDGKSLLDKGDSPAQELVNSLQVFETAAASMDSELHP-LLVQHLPHLYMCLQYPSTAVRHMAARCVGVMSKIATMETMNIFLEKVLPWLGAIDDSVKQEGAIEALACVMEQLDVGIVPYIVLLVVPVLGRMSDQTDSVRFMATQCFATLIRLMPLEAGIPDPPNMSAELIQLKAKERHFLEQLLDGKKLENYKIPVPINAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHCHRAQEYARSKLAECMPLPSLVVCPPTLTGHWVDEVGKFCSR-EYLNPLHYTGPPTERIRLQHQV-KRHNLIVASYDVVRNDIDFFRNIKFNYCILDEGHVIKNGKTKLSKAVKQLTANYRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGVLAMDALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCTLSPLQVQLYEDFAKSRAKCDVDETVSSATLSEETEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEFKTTAEKLAVQNSSLHDIQHAPKLSALKQLLLDCGLG-------NGSTSESGTESVVAQHRILIFCQLKSMLDIVEHDLLKPHLPSVTYLRLDGSIPPGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMNIANTVISQENSSLQSMGTDQLLDLFTLD------------KDGKAEKAD----TSTSGKASMKSILENLSDLWDQEQYDSEYSLENFMHSLK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BGW0-1", "uniprot_id": "A0A8M2BGW0_DANRE", "id": "A0A8M2BGW0-1", "name": "", "aln": "-------MAVSRLERLFILLDTGTTPVTRKAAAQQLGDVVKLHPHELNNLLSKVLTYLRSPNWDTRIAAGQAVEAIVKNIPEWNPSPKPK-----------------DEVCAEDLSPEDVSTDR--LSFYRFDISRLLKHGASLLGSAGAEFELQDDK----SGETDP--KERLARQRKQLQKK--LGLDMGAAIGMDTEELFNDEDLEDACASSTNRTQPGKSLGCHFSRNHLPAAELIDSEFRPG------MSNRQKNKAKRMAKLVAK---------------QRSRD-VDSNEKSNDSFEGEPEEKRRKT-TNVVIEQPANDSKVLIDNVPD---NSSLFEETQEWPLESFCDELCNDLFNPSWEIRHGAGTGLREVLKCHGAGGGKTVGSTAEQMERQHQEWLEDLVIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVALRHMENSGVAMTVDILLKLLT---------EDQWEVRHGGLLGIKYALAVRQDLIAEL--LPRVLPAITEGLRDLDDDVRAVAAAALIPVVDGLVQLQ-PAKVPFIVDTLWNALLELDD-LTASTNSIMTLLSSLLTYPQVRQCSTQQSLT--------VLVPRVWPFLRHTIASVRRAALDTLFTLLSKA-------DQS----------------CAVWLNPIMQDMLRHIFQSCILESNQEILELIQKVWRELLRQAPQQYVVAASCPWMGAWLCLMMQAPHIPID---PNMLLEVK---------ARFKEKAAGKARQG--SVPVKETVQEYIGGAETVTEEPATRDYVVTR--ARLMAAKLLGALCSCICDPR--LNSSSLELRPAESLAQLLLFHLNSKSALQRIAVSMVICEWAGLQKECELLSSVVQPRLLVILSEQLY-------YDEIAIPFTRMQNECKQLIALLADA-----------HIDVRERINS--TVFTIDQANELVTTIFSESTSTLN--LKSRQFQPLDSKRIQAQSTVCETSAEWQQLQLRVHTFTACAVVGLGMLPDKLNPVVRPLMEAARREENSLVQGCAASNIAHLLQLCAARSPCPNA-KIVKNLCSSVCVDPMLTPSAACPVPPASTPIQESSKASVAEKDAMHHMVNKTKGIITLYRH----QKAAFAITSKRGP-TPKTPKSNTNNDLPVG--GSISTETDESKKPCLIQRRGAEFCLMTVARHFSKELTKTLPYLWESMTGPLRNALDAQEFDSSQLLKQGDSVAQDLVNSLQVLEVTAGAMSQELIP-LLMEQLPLLCTCLQHPYTAVRHMAARCVGVLSKIATMETMNVFLEQVLPWLGAIDDNTKQEGAIEALACVMEQLDVDIVPYIVLLVVPVLGRMSDPCDSVRFMATQCFATLIRLLPLEAGIPDPPSMSEDLIRQKARERHFLEQLLDGRKLENYKIPVPIKAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHFLRAQEYTRTKAPDSCPLPSIVVCPPTLTGHWVDEVGKFCSK-EFLNPLHYTGPPTERARLQHQV-KKHNLIVASYDVVRNDVEFFRDIKFNYCILDEGHVIKNGKTKLSKAIKQLTANYRLILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDAKSSSREQEAGVLAMEALHRQVLPFLLRRMKDDVLQDLPPKIIQDYYCNLSPLQVQLYEDFAKSRAKVNVDDVISTASTQEDEEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEYKHITEQLSTQHSSLRDIQHAPKLSALKQLLLDCGLG-------SAGASDSGTEAVVAQHRVLIFCQLKSMLDIVEQDLLKPQLPGVTYLRLDGSVQAGLRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMTIANTVISQENASLQSMGTEQLLNLFTLD------------KDDKAEKCDG--SSSSSGKSSMKSVLDGLGDLWDQQQYENEYDLGTFMHSLK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VF02-1", "uniprot_id": "Q9VF02_DROME", "id": "Q9VF02-1", "name": "", "aln": "--------MTSRLDRLFILLETGSTAATRQAAAKQIGEVQKLYPHELHALLNRLVGYLHSTSWETRIAAAQTVEAILKQVPPWQPEFQVLPKKERCATNTATAAAAAEEDSCQSSGSNSTTASERLLSFDEFDLQQILHKGARLIGSEGNEFDVQEEQPASGGGEEDRSLASRLSRQRAVLNDK--LGLTTAAKLGVNLTDMITDEDVALNRSGSTYNVN----------AEKLPVEHLLNIKTAANGSGQAPLSCREMNRAKRKARQNTSGCSVTAVTPTCSRRNSNSNHSTGSNHSSNGTTGAAIEEPEKKK-LKSTDRQEIFYS--LNAAVPD---ATGTWVDAVSWPLENFCSRLFIDLFHAKWEVRHGAATALRELINQHAQGAGKAVLQTREQMDEAHSRWLEDAALRLLCVLCLDRFGDFVSDQVVAPVRETCAQVLGTLVKEMEASKVQRIVNILLQLIQH--------KNEWDVRHGGLLGLKYVFVVREELLPIY--LPQSISNILIGLLDAVDDVGAVAAATLIPVSSWLPKLLNPAQVSSIVKMLWDLLLDQDE-LTSACNSFMGLLAAILCLPNAARWVEMEPMA--------ILVPRLWPFLSHSTSSVRRSTLKTLMTLTSADRVKSEPKDENQVKEEADKEEMKLNFGVSDWKWELLQQALRHIYQRILVEPQADIQALARQVWSNLIQHADLGALLHAACPFVSSWICLSMQPPRLAFD---AGVLIRAGGDVSTPGSTSRKRTPRIGDELGGNILAQSNASLKLYLGGSEATPLD--VRDANFMR--ARISSSRALGALSHYLVQPAPGVVYTPQTESPTDCYTKVLLGHLNAHSAVQRIVCGLIIAFWALEDEPVRPGPPNLQEKLHQCVSEYVY-------YDEVAISLTRLLQEAQDFIATLKQN-----------KIPINDFNNA--KILTLDQIEAVATTLS-ENLRSYP--LKPKVLDMLEERRRSLQASYQQTTSEQSAYHVSAQAALAGAICALHCLPDKLNPVVKPLMESIKREQCLQLQQLSAEFLVHLMDQVCDRNPSPNS-KILNNLCTLLRSDPEFTPKLVMPLETLKQTPVSSEVINNCVYYGILTLALQQTVTTTNTRSGAGGATTPTATTAPRGPGRPPTGEILSATNATAHIELKAQQAKEAEAKQCRIQRLGAACAIEKLCRIFGEQIIEKVAVFQHLMFGKVEQFVKEAYDWRLGSLLPDLGVCNELVSSMQLIETAAPHLHVALHP-QMFALLPSLGFIVCHPLKAVRHMAARCIAVLAEIDACQTMQFVVHDLLPLLGKIEQLIERQGAIEAIERVVSRLQIKVVPYIVLLVVPLLGAMSDPDESVRLLSTHCFANLVQLMPLDG--KTEQLKSDPLQARKTRDREFLDYLFNPKSIPNYKVPVPISVELRCYQQAGINWLWFLNKYNLHGILCDDMGLGKTLQTICILAGDHMHR-------QTANLANLPSLVICPPTLTGHWVYEVEKFLDQGSVLRPLHYYGFPVGREKLRSDIGTKCNLVVASYDTVRKDIDFFSGIHFNYCVLDEGHIIKNGKTKSSKAIKRLKANHRLILSGTPIQNNVLELWSLFDFLMPGFLGTEKQFVQRFSRPILSSRDAKSSAKEQEAGVLAMEALHRQVLPFLLRRVKEDVLKDLPPKITQDLLCELSPLQLRLYEDFSNKHLKDCLDKLGDSSSASMVTEN--LSAKTHIFQALRYLQNVCNHPKLVLR-QSEELTKVTSQLALSNSSLDDIEHSAKLPALKQLLLDCGIG-------VQTES-------VSQHRALIFCQLKAMLDIVEQDLLRRHLPSVTYLRLDGSVPASQRQDIVNNFNSDPSIDVLLLTTMVGGLGLNLTGADTVIFVEHDWNPMKDLQAMDRAHRIGQKKVVNVYRLITRNSLEEKIMGLQKFKILTANTVVSAENASLQTMGTSQIFDLFNGG------------KDKGAESGSSAVQGTASGGMSMNTIIENLPELWSEHQYEEEYDLGNFVQALKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32333-1", "uniprot_id": "BTAF1_YEAST", "id": "P32333-1", "name": "TATA-binding protein-associated factor MOT1", "aln": "-----MTSRVSRLDRQVILIETGSTQVVRNMAADQMGDLAKQHPEDILSLLSRVYPFLLVKKWETRVTAARAVGGIVAHAPSWDPN---------------------ESDLVGGTNEGSPLDNAQVKLEHEMKIKLEEATQNNQLNLLQEDHHLSSLS----DWKLNEILKSGKVLLASSMNDYNVLGKADDNIRKQAKTDDIKQETSMLNASDKANENK---------SNANKKSARMLAMARRKK-------KMSAKNTPKHPVDITES---------------SVSKTLLNGKNMTNSAASLATSPTSNQLNPKLEITEQADESKLMIESTVRPLLEQHEIVAGLVWQFQGIYELLLDNLMSENWEIRHGAALGLRELVKKHAYGVSRVKGNTREENNLRNSRSLEDLASRLLTVFALDRFGDYVYDTVVAPVRESVAQTLAALLIHLDSTLSIKIFNCLEQLVLQDPLQTGLPNKIWEATHGGLLGIRYFVSIKTNFLFAHGLLENVVRIVLYGLNQSDDDVQSVAASILTPITSEFVKLN-NSTIEILVTTIWSLLARLDDDISSSVGSIMDLLAKLCDHQEVLDILKNKALEHPSEWSFKSLVPKLYPFLRHSISSVRRAVLNLLIAFLSIK-------DDS----------------TKNWLN---GKVFRLVFQNILLEQNPELLQLSFDVYVALLEHYKVKHTEKTLDHVFSKHLQPILHLLNTPVGEKGKNYAMESQYILK-----PSQHYQLHPEKKRSISETTTDSDIPIPKNNEHINIDAPMIAGDITLLGLDVILNTRIMGAKAFALTLSM--FQDSTLQSFFTNVLVRCLELPFSTPRMLAGIIVSQFCSSWLQKHPEGEKLPSFVSEIFSPVMNKQLLNRDEFPVFRELVPSLKALRTQCQSLLATFVDVGMLPQYKLPNVAIVVQGETEAGPHAFGVETAEKVYGEYYDKMFKSMNNSYKLLAKKPLEDSKHRVLMAINSAKESAKLRTGSILANYASSILLFDGLPLKLNPIIRSLMDSVKEERNEKLQTMAGESVVHLIQQLLENNKVNVSGKIVKNLCGFLCVDTSEVPDFSVNAEYKEK---------------ILTLIKE-----------------------------------------SNSIAAQDDINLAKMSEEAQLKRKGGLITLKILFEVLGPSILQKLPQLRSILFDSLSDHENEEAS------KVDNEQGQKIVDSFGVLRALFPFMSDSLRSSEVFTRFPVLLTFLRSNLSVFRYSAARTFADLAKISSVEVMAYTIREILPLMNSAGSLSDRQGSTELIYHLSLSMETDVLPYVIFLIVPLLGRMSDSNEDVRNLATTTFASIIKLVPLEAGIADPKGLPEELVASRERERDFIQQMMDPSKAKPFKLPIAIKATLRKYQQDGVNWLAFLNKYHLHGILCDDMGLGKTLQTICIIASDQYLRKEDYEKTRSVESRALPSLIICPPSLTGHWENEFDQYAPF---LKVVVYAGGPTVRLTLRPQL-SDADIIVTSYDVARNDLAVLNKTEYNYCVLDEGHIIKNSQSKLAKAVKEITANHRLILTGTPIQNNVLELWSLFDFLMPGFLGTEKMFQERFAKPIAASRNSKTSSKEQEAGVLALEALHKQVLPFMLRRLKEDVLSDLPPKIIQDYYCELGDLQKQLYMDFTKKQKNVVEKDIENSEIAD---------GKQHIFQALQYMRKLCNHPALVLSPNHPQLAQVQDYLKQTGLDLHDIINAPKLSALRTLLFECGIGEEDIDKKASQDQNFPIQNVISQHRALIFCQLKDMLDMVENDLFKKYMPSVTYMRLDGSIDPRDRQKVVRKFNEDPSIDCLLLTTKVGGLGLNLTGADTVIFVEHDWNPMNDLQAMDRAHRIGQKKVVNVYRIITKGTLEEKIMGLQKFKMNIASTVVNQQNSGLASMDTHQLLDLFDPDNVTSQDNEEKNNGDSQAAKGMEDIANETGLTGKAKEALGELKELWDPSQYEEEYNLDTFIKTLR-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:* .**::**:* ..*: **.*:*:: * :*.:: **.:: :* .*:**::*.::* .*: : * *:* :. . . .:.: :. :..:.. . . : : . ::. ** : :.:* :. : : .:: . * .*: . . . *. :. :*.: . .: : : : : * ::.: . * :*: .**:****. .***::: *. . .: .* *: :.. *** . *** *:.******:* * *******: **.*.. : .:: : .: * :*: :. *:. ******::* . :: :.: * . : : ** : *** :***: * *: . : * : :: :*. * *: :::: .*:* **: : :. :.: ***:::*** *: :****:.*. *::: * *:. * . :* ::* ::* . :: * .*: *: : : .. : :: . ... . :. . : . . . : . . . : :: :** . : . . :: : * :.: : * . . . * . . . :. : :.: : : *:. .:. : :.:.::: : : * : : : :: . : : : : . *:. : : .:. . . : * :: : ** ****:::.**:: :.*. :* :.. :.:*:: .. : *:::*** : *. .* . : : . : ::* *. : : . :. .: .:. : : . : . . :.:*.*: ::. : * . :. :* * : ...*: *** .. :::* : :.* :..:** :. . .::*: * : : :: ::**:::*:**:** *** :.** ::* **.:::*:**:. . * : ::*.*:: ::: . :*:*:.*.. ** *** *:*** *****:****************:***:*.*: * : : ***:::***:***** *. :: *. : * * *. * *: :: . :::*:***..*:*: .: .:***:*****:***.::* :**:*.:.**:*:**:**************************: * *:.:** :**::::*::********::***:*****:***:*:***.****** ** * *. ** :** **::.: : .. .: . .. *:****:*::::**** *** : : . * .* ** ::.**.**: **::**:* ::*** ******* ***:**:**:: :*.***:*****: . *:.:* .**.***** ***** **************:*********.**************:******:**:.:************: *.**:. :*:.* :*.* *:::** . * * . :. . : : * :**. **:.**.* .*:::*. ", "identical_positions": 488, "similar_positions": 557, "identity": "23.95%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021028-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06748-1", "uniprot_id": "NPM_HUMAN", "id": "P06748-1", "name": "Nucleophosmin", "aln": "MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPKVEAKFINYVKNCFRMTDQEAIQDLWQWRKSL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61937-1", "uniprot_id": "NPM_MOUSE", "id": "Q61937-1", "name": "Nucleophosmin", "aln": "MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEDEEDVKLLGMSGKRSAPGGGNKVPQKKVKLDEDDEDDDEDDEDD-EDDDDDDFDEEETEEKVPVKKSVRDTPAKNAQKSNQNGKDLKP-STPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPKVEAKFINYVKNCFRMTDQEAIQDLWQWRKSL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FCU0-1", "uniprot_id": "E7FCU0_DANRE", "id": "E7FCU0-1", "name": "Nucleophosmin", "aln": "------MDLEQMGPQTFLYGCELKAGKDITFNPEDDDYDHQLSVRMACVDPSTKDELNVVEIEGQDSEGQKVKAVLATLKPSTLPSVCLGGFEITPPVVFRLRTGSGPVHISGQHLVIMGGDQSFDEEEEEEEEEETVMTSKKRPALSTPKPSKKMKMDEEDDDDDDEDDDD-EDDDE----EDESEEESPVKE--KKAPAK-PKTPTQNGKGPKP-STPAKQTPQKGKK-EQTPKTPQTPRTLADIKSKMMESVAKGVSLPKVQLKFENYVNNCFKGTDPKVVEELWKWRQTVK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:. : **.:*:******.** *: ::*: :****:* ..:...:****::** *. : **. :*..***** *. *:*.***********:**: ************* : * . ::*:**: : : .:. *. .. *.**:*: :::***::::** ****: ::*:**: ***: :.:*** .:...****. ** *** .: :. ** *:*****: * :: ***:** *: ** *****: ** ***:***: ** :.:::**:**::: ", "identical_positions": 136, "similar_positions": 94, "identity": "46.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021030-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K4F8-1", "uniprot_id": "CCNF_RAT", "id": "Q8K4F8-1", "name": "Cyclin-F", "aln": "MGSGGVIHCRCAKCFCYPTKRRIKRRPRNLTILSLPEDVLFHILKWLSVGDILAVRAVHSHLKYLVDNHASVWASASFQELWPSPQNLKLFERAAEKGNFEAAVKLGIAYLYNEGLSVSDEACAEVNGLKASRFFSMAERLNTG-SDPFIWLFIRPPWSVSGSCCKAVVHDSLRAECQLQRSHKASILHCLGRVLNLFEDEEKRKQAHNLFEESAHQGCLASSYLLWESDRKVDMSDPGRCLHSFRKLRDYAAKGCWEAQLALAKACAGGSQLGLEGKACSESVCQLFQASQAVNKQQIFSVQKGLSDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYKLQLLGIACMVICTRFISKEILTIREAVWLTDNTYKYEDLVRVMGEIISALEGKIRIPTVVDYKEVLLTLVPVAPRTQHLCSFLCELTLLHTSLSVYAPARLASAALLLARLMHGHTQPWTTQLWDLTGFSYSDLTPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKCYEEISQEEVLSYAELCSALGVKQESPEPPSFPSSG---EIHTFLSSPSGRRSKRKRENSLQEDRGSFVTTPTAELSNQEETLLGSLLDWSLD-CCSGYEGDQESEGEKEGDVTAPSGLLDVTVVYLNPEEHCCQESSDEEVWPEDKSHPTP-----GTQAPPASAPWPLPCNRGDPGKDVTTSGYSSVSSSSPISSLDGGMVGSPRSTSVLSVGSHSSTKPCYHQAKKSCLQCRPPNPPESGAHQQPVKRQNLSVHSDE-DTNLGFLKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51944-1", "uniprot_id": "CCNF_MOUSE", "id": "P51944-1", "name": "Cyclin-F", "aln": "MGSGGVIHCRCAKCFCYPTKRRIKRRPRNLTILSLPEDVLFHILKWLSVGDILAVRAVHSHLKYLVDNHASVWASASFQELWPSPQNLKLFERAAEKGNFEAAVKLGIAYLYNEGLSVSDEACAEVNGLKASRFFSMAERLNTG-SEPFIWLFIRPPWSVSGSCCKAVVHDSLRAECQLQRSHKASILHCLGRVLNLFEDEEKRKQARSLLEESSRQGCLISSYLLWESDRKVDMSDPGRCLHSFRKLRDYAAKGCWEAQLALAKACAGGSQLGLEGKACSESVCQLFQASQAVNKQQIFSVQKGLSDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYKLQLLGIACMVICTRFISKEILTIREAVWLTDNTYKYEDLVRVMGEIISALEGKIRIPTVVDYKEVLLTLVPVAPRTQHLCSFLCELTLLHTSLSIYAPARLASAALLLARLMHGQTQPWTTHLWDLTGFSYSDLVPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKCYEEISREEVLSYADLCSTIGVKQESPEPPSFPSSG---EIHTFLSSPSGRRSKRKRENSLQEDRGSFVTTPTAELSNQEETLLGSLLDWSLE-CCSGYEGDQESEGEKEGDVTAPSRLLDVTVVYLNPEEHCCQESSDEEAWPEDKIHPAP-----GTQAPPASAPRPLLCNRGDRAKDITTSGYSSVSSSSPISSLDGGMGGSPQSTSVLSVGSHSSTKPCHHQAKKSCLQCRPPNSPESGVHQQPVKRQNLSVHSDK-DMHLAS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41002-1", "uniprot_id": "CCNF_HUMAN", "id": "P41002-1", "name": "Cyclin-F", "aln": "MGSGGVVHCRCAKCFCYPTKRRIRRRPRNLTILSLPEDVLFHILKWLSVEDILAVRAVHSQLKDLVDNHASVWACASFQELWPSPGNLKLFERAAEKGNFEAAVKLGIAYLYNEGLSVSDEARAEVNGLKASRFFSLAERLNVG-AAPFIWLFIRPPWSVSGSCCKAVVHESLRAECQLQRTHKASILHCLGRVLSLFEDEEKQQQAHDLFEEAAHQGCLTSSYLLWESDRRTDVSDPGRCLHSFRKLRDYAAKGCWEAQLSLAKACANANQLGLEVRASSEIVCQLFQASQAVSKQQVFSVQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVELRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGFSYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRYGEISQEEVLSYSQLCAALGVTQDSPDPPTFLSTG---EIHAFLSSPSGRRTKRKRENSLQEDRGSFVTTPTAELSSQEETLLGSFLDWSLD-CCSGYEGDQESEGEKEGDVTAPSGILDVTVVYLNPEQHCCQESSDEEACPEDKGPQDPQALALDTQIPATPGPKPLVRTSREPGKDVTTSGYSSVSTASPTSSVDGGLGALPQPTSVLSLDSDSHTQPCHHQARKSCLQCRPPSPPESSVPQQQVKRINLCIHSEEEDMNLGLVRL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYX6-1", "uniprot_id": "CCNF_DANRE", "id": "Q6NYX6-1", "name": "Cyclin-F", "aln": "MKAG-ALHCRCAKCFSLPVRKRVRKRASAVSLLSLPEELLVFVLQCLSAEDLLSVRAVHSHLCDIIDTNASIWARVSFKDRWPAPDTVWLFERAAEKGNFEAAVKLGIAYLYNEGPLLSEEGRADLCGRMASRYLSLSESLRSPQAEPFIWLFIRPPWSVSGSCCKAVVFDRLQAECQTSPGRKGTLLYCLARVLQLFDDEEKRDEAELMLKESSRCGSLQSSYLLWAISRASSTADPGRYLQCMRTLRDYAARGCWEAQLAFVKSCGSANPLGLEPRACSELVSQFFQTGPSALRYQPHLQGQDIT-TKRYILVDWLVEVTTTKDFSSQVLHVTISCVDRYLHLRSVPKAQLQLLGIACMVICTRFISKEILTIREAVWLTDNTYQYEDLVHMMGEVISVLDGKIRTPTVLDYGEVLLSLLPVERRTAHLFSYICELSLLCSPATVPGPARLASAILLLTRALHNYVPVWPVQLEENTGFSKQDLVSCALTLYIKCFGQDVPKDYRHVSLTGVKQRFEDDSYQQISKDTVMGFKELCHVLEVPEVEPQVEVSSTSGQITEMHTFLSSPTSS-SKRRRADSMQAHRGAFVATPTAELSNQEETLLGDFLDWSLDTSCSGYEGDRESEGEKDGEISTMEVQMELPLDCADRQTHCCLLSSDDTSLCEEDEQEPP---------TGGSKPWTRHLSSSSTSSSSSSCGFCTDRHSSGYSSIQS----FPSPTGSSALVSPQNPPGVPSQRIRRQVKRKNTAAHSAGEAEQEDDAANLAFLSF-----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :* .:********. *.::*:::*. :::*****::*..:*: **. *:*:******:* ::*.:**:** .**:: **:* .: ************************** :*:*. *:: * ***::*::* *. : **********************.: *:**** . :*.::*:**.***.**:****:.:*. :::*::: *.* ****** .* . :**** *:.:*.******:*******::.*:*.... **** :*.** *.*:**:. :. : * . :.:. * ****:******:* ***:* **:*:.******: * **: :**********************************:*****::***::*.*:**** ***:** ****:*:** ** ** *::***:** :. : .*****:* ***:* *. . *..:* : **** .** .*.*:*: *** :*.*****:****.*******. * :**:: *:.: :** .: * : .*: ::* *:*:*****:. :**:* :*:* .**:**:*******.*******.:*****: .*******:******:*:::: . :::.: : : *** ***: *:. * . . * . . . ... ::.*:.: :* **::. * .*. :: * . . * : :: : . . .:. :* . **.. * ", "identical_positions": 380, "similar_positions": 227, "identity": "48.04%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021030-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P32232-1", "uniprot_id": "CBS_RAT", "id": "P32232-1", "name": "Cystathionine beta-synthase", "aln": "MPSGTSQCEDGSAG--CPQDLEVQPEKGQLEKGASGDK------------------------------------ERVWISPDTPSRCTWQLGRPMADSPHYHTVPTKSPKILPDILRKIGNTPMVRINRISKNAGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERAGTLKPG-DTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDDTAEEILQQCDG-----KVDMLVASAGTGGTITGIARKLKEKCPGCKIIGVDPEGSILAEPEELNQTEQTAYEVEGIGYDFIPTVLDRAVVDRWFKSNDDDSFAFARMLISQEGLLCGGSSGSAMAVAVKAAQ---ELKEGQRCVVILPDSVRNYMSKFLSDKWMLQKGFMK-EELSVKRP------------WWWHLRVQELSLSAPLTVLP-TVTCEHTIAILREKGFDQAPVVN-ESGAILGMVTLGNMLSSLLAGKVRPSDEVCKVLYKQFKPIHLTDTLGMLSHILEMDHFALVVHEQIQSRDQAWSGVVGGPTDRNNGVSSKQLMVFGVVTAIDLLNFVAAREQTRK-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WT9-1", "uniprot_id": "CBS_MOUSE", "id": "Q91WT9-1", "name": "Cystathionine beta-synthase", "aln": "MPSGTSQCEDGSAG--GFQHLDMHSEKRQLEKGPSGDK------------------------------------DRVWIRPDTPSRCTWQLGRAMADSPHYHTVLTKSPKILPDILRKIGNTPMVRINKISKNAGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERAGNLKPG-DTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDDTAEEILQQCDG-----KLDMLVASAGTGGTITGIARKLKEKCPGCKIIGVDPEGSILAEPEELNQTEQTAYEVEGIGYDFIPTVLDRAVVDKWFKSNDEDSFAFARMLIAQEGLLCGGSSGSAMAVAVKAAR---ELQEGQRCVVILPDSVRNYMSKFLSDKWMLQKGFMK-EELSVKRP------------WWWRLRVQELSLSAPLTVLP-TVTCEDTIAILREKGFDQAPVVN-ESGAILGMVTLGNMLSSLLAGKVRPSDEVCKVLYKQFKPIHLTDTLGTLSHILEMDHFALVVHEQIQSRDQAWSGVVGGPTDCSNGMSSKQQMVFGVVTAIDLLNFVAAREQTQT-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35520-1", "uniprot_id": "CBS_HUMAN", "id": "P35520-1", "name": "Cystathionine beta-synthase", "aln": "MPSETPQAEVGPTG--CPHRSGPHSAKGSLEKGSPEDKE---------------------------------AKEPLWIRPDAPSRCTWQLGRPASESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPG-DTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDG-----KLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQ---ELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKP------------WWWHLRVQELGLSAPLTVLP-TITCGHTIEILREKGFDQAPVVD-EAGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYH--------------STGKSSQRQMVFGVVTAIDLLNFVAAQERDQK-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N4Z7-1", "uniprot_id": "A0A8M1N4Z7_DANRE", "id": "A0A8M1N4Z7-1", "name": "Cystathionine beta-synthase", "aln": "MPAVPSSSESVGTGPVCPHAAKMLSNAANGESGINGDADDVFNGKAGHKLNETNGRHLKSLNGQHMDKGSEVSMERKWIRPDLPSRCTWKLGDLNMESPHNHYQRTKTSGILPNILSKIGETPMVRMNKIPKAFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPG-DTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTSARFDSPESHVGVAWRLKNEIPNAHILDQYRNPSNPLAHYDTTAEEILEQCGG-----KIDMLVAGAGTGGTITGIARKLKEKCPDIKIIGVDPEGSILAEPDELNKTDKTQYEVEGIGYDFIPTVLDRSVVDNWYKSNDEESFAMSRMLIREEGLLCGGSSGTAMSAAVNVAK---ELKEGQRCVVILPDSIRNYMSKFLSDKWMFEKGFMSEEDLVVNKP------------WWWNLTLQELRLSAPLTVLP-LVSIKKTIQILKEKAFDQAPVVD-EAGHILGMVTLGNMLASVLAGKVRPSDPISKVLYKQFKQVRLTDNLGKLSRILETDHFALVVHEQIQYM--------------SDGSPKMRQMVFGVVTAIDLLNYVTMRERRERTLSECSLSEDQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRD9-1", "uniprot_id": "Q9VRD9_DROME", "id": "Q9VRD9-1", "name": "Cystathionine beta-synthase", "aln": "MPQPKPYER-----------------------------------------------------------------PADFIDPGKPSKCKWHLG-TAEKSPHIHRGIAHRQQITPNILEVIGCTPLVKLNNIPASDGIECEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLKPG-YTIIEPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTEAAYDSPEGLIYVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLDN-----KVDMIVVSAGTAGTISGIGRKIKEQVPSCQIVGVDPYGSILARPAELNKTDVQFYEVEGIGYDFPPTVFDDTVVDVWTKIGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALEHAR---KLKKGQRCVVILPDGIRNYMTKFVSDNWMEARNFKE--PVNEHGH------------WWWSLAIAELELPAPPVILKSDATVGEAIALMKKHRVDQLPVVDQDDGSVLGVVGQETLITQIVSMNRQQSDPAIKALNKRVIRLNESEILGKLARVLEVDPSVLILGK----------------------NPAGKVELKALATKLDVTTFIAAGKQKPKANGTTNGGSH-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32582-1", "uniprot_id": "CBS_YEAST", "id": "P32582-1", "name": "Cystathionine beta-synthase", "aln": "----------------------------------------------------------------------------------------------MTKS-------EQQADSRHNVIDLVGNTPLIALKKLPKALGIKPQIYAKLELYNPGGSIKDRIAKSMVEEAEASGRIHPSRSTLIEPTSGNTGIGLALIGAIKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAAAWDSPESHIGVAKKLEKEIPGAVILDQYNNMMNPEAHYFGTGREIQRQLEDLNLFDNLRAVVAGAGTGGTISGISKYLKEQNDKIQIVGADPFGSILAQPENLNKTDITDYKVEGIGYDFVPQVLDRKLIDVWYKTDDKPSFKYARQLISNEGVLVGGSSGSAFTAVVKYCEDHPELTEDDVIVAIFPDSIRSYLTKFVDDEWLKKNNLWDDDVLARFDSSKLEASTTKYADVFGNATVKDLHL-KPVVSVKETAKVTDVIKILKDNGFDQLPVLT-EDGKLSGLVTLSELLRKLSINNSN-NDNTIKGKYLDFKKLNNFNDVSSYNENKSGKKKFIKFDENSKLSDLN-----RFFEKNSSAVITDGLKPIHIVTKMDLLSYLA------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* : ::: :* **:: ::.: *:: :: ** *: *.***:****. *:::** * ::*. *:*************: *::**: **.:***** ***..*::***:*:**** * :****. : ** :*:.* *.: :****.* ** *** *. ** * . :: :*...**.***:**.: :**: :*:*.** *****.* :**:*: *:******** * *:* ::* * * .*. .* :* * :**:* ***:* :. ..:: .. :* :.: *.*:**.:*.*::**:.*.*: ..: . : : : :* * * . : . ..* :::.: .** **: : * : *:* :: .: : . .* * . :. : :. . . . : . : :.* :*: .::: ", "identical_positions": 156, "similar_positions": 154, "identity": "24.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021030-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZMM2-1", "uniprot_id": "A0A8I5ZMM2_RAT", "id": "A0A8I5ZMM2-1", "name": "Multifunctional protein CAD", "aln": "MVPPLTCMVPPLTLPAACAVAVVLQLTTLRAPACRSRLLSSAPRSEPRGPTPARGVCLVPVGLAAPPASRCSPCLSSDPMAALVLEDGSVLQGRPFGAAVS-------TAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNYGIP---SDEEDEFGLSKWFESSE--IHVAGLVVGECCPTPSHWSATCTLHEWLQQHGIPGLQGVDTRELTKKLREQGSLLGKLVQKGTEPS-----------ALP---FVDPNARPLAPEVSIKTPRVFNA--------------GGAPRIFAVDCGLKYNQIRCLCQLGAEVTVVPWNHELDSRKYDGLFLSNGPGDPASYPGVVSTLNRVLSEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGTGRCFLTSQNHGFAVDADSLPAGWAPLFTNANDCSNEGIVHDNLPFFSVQFHPEHRAGPSDMELLFDVFLETVRDTVAGNAEGRTVRERLAQRLCPPELPIPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGILLTFGGQTALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGFASTKEELSALVAPAFAHTSQVLIDKSLKGWKEIEYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRRTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRNSVTGG-TAAFEPSLDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKALRMVDENCVGFDHTVKPVSDV----ELETPTDKRIFVVAAALWAG-YSVERLYELTRIDCWFLHRMKRIVTHAKLLEQHRG--RPLPQDLLHQAKCLGFSDKQIALAVLSTELVVRKLRQELGICPAVKQIDTVAAEWPAQTNYLYLTYWGNTHDLDFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQQLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLPNNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQTVGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAVACDGIVSAIAISEHVENAGVHSGDATLVTPPQDITPKTLERIKAIVHAVGQELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRIIMGEKVESVGLMTG-SGVVGVKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIGSYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECP---PQRSILDQLAENHFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEALGQIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHK--EDFASGTAAALAGGVTMVCAMPN--TRPPIIDAPALALAQKLAEAGARCDFTLFLGASSENAGTLGAVAGSAAGLKLYLNETFSELRLDSVAQWMEHFETWPSHLPIVAHAERQSVAAVLMVAQLTRRSVHICHVARKEEILLIKTAKAQGLPVTCEVAPHHLFLNREDLERLGPGKGEVRPELGSREDMEALWENMAVIDCFASDHAPHTLEEKCGPKPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIFHLPLQEDTYVEVDLEHEWTVPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLVPPGYGQDVRKWPQG--AVPQPPPPTPTTTEITTTPERPRRVIPG-------------LPDGRFHLPPRIHRASDPGLPAMYLRPGAGISWGSRAWAEEPKEKPPRKVAESELIGTPDGPCYPVPPVPRQASPQNLGSSGLLHPQMSPLLHSLVGQHILSVKQFTKDQMSHLFNVAHTLRMMVQKERSLDILK-GKVMASMFYEVSTRTSSSFAAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCRRPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVSLRYVAPPSLRMPSSVWDFVASRGTK-QEEFESIEEALPDTDVLYMTRIQKERFGSSQEYEACFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLATVLGRF----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RQC6-1", "uniprot_id": "PYR1_MOUSE", "id": "B2RQC6-1", "name": "Multifunctional protein CAD", "aln": "-------------------------------------------------------------------------------MAALVLEDGSVLQGRPFGAAVS-------TAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNYGIP---SDEEDEFGLSKWFESSE--IHVAGLVVGECCPTPSHWSANCTLHEWLQQRGIPGLQGVDTRELTKKLREQGSLLGKLVQKGTEPS-----------ALP---FVDPNARPLAPEVSIKTPRVFNA--------------GGAPRICALDCGLKYNQIRCLCQLGAEVTVVPWDHELDSQKYDGLFLSNGPGDPASYPGVVSTLSRVLSEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGTGRCFLTSQNHGFAVDADSLPAGWAPLFTNANDCSNEGIVHDSLPFFSVQFHPEHRAGPSDMELLFDVFLETVREAAAGNIGGQTVRERLAQRLCPPELPIPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATVQTSQGLADKVYFLPITLHYVTQVIRNERPDGVLLTFGGQTALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGFASTKEELSALVAPAFAHTSQVLIDKSLKGWKEIEYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRRTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRNSVTGG-TAAFEPSLDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKALRMVDENCVGFDHTVKPVSDM----ELETPTDKRIFVVAAALWAG-YSVERLYELTRIDCWFLHRMKRIVTHAQLLEQHRG--QALPQDLLHQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAVKQIDTVAAEWPAQTNYLYLTYWGNTHDLDFRAPHVLVLGSGVYRIGSSVEFDWCAVGCIQQLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLPNNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCHTVGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAVACDGIVSAIAISEHVENAGVHSGDATLVTPPQDITPKTLERIKAIVHAVGQELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRIIMGEKVEPVGLMTG-SGVVGVKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPEKNILLTIGSYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECP---PQRSILDQLAENHFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEALGQIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHK--EDFASGTAAALAGGVTMVCAMPN--TRPPIIDAPALALAQKLAEAGARCDFTLFLGASSENAGTLGAVAGSAAGLKLYLNETFSELRLDSVAQWMEHFETWPAHLPIVAHAERQSVAAVLMVAQLTQRPVHICHVARKEEILLIKTAKAQGLPVTCEVAPHHLFLNREDLERLGPGKGEVRPELGSREDMEALWENMAVIDCFASDHAPHTLEEKCGPKPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIFHLPLQEDTYVEVDLEHEWTVPSHMPFSKARWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLVPPGYGQDVRKWPQG--VVPQPPPSTPATTEITTTPERPRRVIPG-------------LPDGRFHLPPRIHRASDPGLP-----------------AEEPKEKPPRKVVEPELMGTPDGPCYPAPPVPRQASPQNLGSSGLLHPQMSPLLHSLVGQHILSVKQFTKDQMSHLFNVAHTLRMMVQKERSLDILK-GKVMASMFYEVSTRTSSSFAAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVIVLRHPQPGAVELAAKHCRRPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVSLRYVAPPSLRMPPSVRDFVASRGTK-QEEFESIEEALPDTDVLYMTRIQKERFGSVQEYEACFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLATVLGRF----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27708-1", "uniprot_id": "PYR1_HUMAN", "id": "P27708-1", "name": "Multifunctional protein CAD", "aln": "-------------------------------------------------------------------------------MAALVLEDGSVLRGQPFGAAVS-------TAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNYGIP---PDEMDEFGLCKWFESSG--IHVAALVVGECCPTPSHWSATRTLHEWLQQHGIPGLQGVDTRELTKKLREQGSLLGKLVQNGTEPS-----------SLP---FLDPNARPLVPEVSIKTPRVFNT--------------GGAPRILALDCGLKYNQIRCLCQRGAEVTVVPWDHALDSQEYEGLFLSNGPGDPASYPSVVSTLSRVLSEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTSQNHGFAVETDSLPADWAPLFTNANDGSNEGIVHNSLPFFSVQFHPEHQAGPSDMELLFDIFLETVKEATAGNPGGQTVRERLTERLCPPGIPTPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGVLLTFGGQTALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGFASNREELSALVAPAFAHTSQVLVDKSLKGWKEIEYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRNSVTGG-TAAFEPSVDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKALRMVDENCVGFDHTVKPVSDM----ELETPTDKRIFVVAAALWAG-YSVDRLYELTRIDRWFLHRMKRIIAHAQLLEQHRG--QPLPPDLLQQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAVKQIDTVAAEWPAQTNYLYLTYWGTTHDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQQLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLPNNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQTVGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAVASDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPVGLMTG-SGVVGVKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIGSYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECP---PQRSILEQLAEKNFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEALGQIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHK--EDFASGTAAALAGGITMVCAMPN--TRPPIIDAPALALAQKLAEAGARCDFALFLGASSENAGTLGTVAGSAAGLKLYLNETFSELRLDSVVQWMEHFETWPSHLPIVAHAEQQTVAAVLMVAQLTQRSVHICHVARKEEILLIKAAKARGLPVTCEVAPHHLFLSHDDLERLGPGKGEVRPELGSRQDVEALWENMAVIDCFASDHAPHTLEEKCGSRPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIFHLPPQEDTYVEVDLEHEWTIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLVPPGYGQDVRKWPQG--AVPQLPPSAPATSEMTTTPERPRRGIPG-------------LPDGRFHLPPRIHRASDPGLP-----------------AEEPKEKSSRKVAEPELMGTPDGTCYPPPPVPRQASPQNLGTPGLLHPQTSPLLHSLVGQHILSVQQFTKDQMSHLFNVAHTLRMMVQKERSLDILK-GKVMASMFYEVSTRTSSSFAAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCRRPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVSLRYVAPPSLRMPPTVRAFVASRGTK-QEEFESIEEALPDTDVLYMTRIQKERFGSTQEYEACFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLATVLGRF----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AL15-1", "uniprot_id": "A0A8M3AL15_DANRE", "id": "A0A8M3AL15-1", "name": "Multifunctional protein CAD", "aln": "---------------------------------------------------------------------------MSLKMASLVLEDGTTFKGRLFGAVSS-------VSGEVVFQTGMVGYPEALTDPSYKSQILTLTYPMIGNYGIP---KDEDGEFGLSKWFESSQ--IHAAALIVGEVSENPSHWSAAKSLDEWLREQGIPGLQGVDTRCLTKKIREKGTMLGKLVVEGTPAD-----------NIP---FDNPDARNLVKEVSMKAPKVFNP--------------EGTVRITAIDCGIKYNQIRCLCQRGARVTVVPWDQPLDSNDFDGLFISNGPGNPEYCKETVENIRKVACVENPKPIFGICLGHQLLSLVIGAKTYKMKYGNRGHNQPCIHKGTSRCYITSQNHGFAVDPETLPKDWDVLFTNANDQTSEGIVHNHKPLFSVQFHPEHMAGPTDLVGLFDVFLDTVRDVKE-NKAGKSVKQRLMEHLTFPGSPDP-NAFVRPRKVLVLGSGGLSIGQAGEFDYSGSQAIKAMKEENIQTILINPNIATVQTSKGLADKVYFLPITPEYVTQVIKNERPDGVLLTFGGQTALNCGVELKKQGVLEKYKVRVLGTPVASIEMTEDRKIFVEKMEEINEHVAPSEAAMSVEQAVAAAERLGYPVLVRSAFALGGLGSGFANNRDEMITLVTQAFAHTSQVLVDKSLKGWKEIEYEVVRDAYDNCVTVCNMENIDPLGIHTGESIVVAPSQTLNDYEYNMLRNTAIKVIRHLGVVGECNIQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLSLGIPLPVLKNSVTNSTTANFEPSLDYCVVKVPRWDLSKFLRVSTKIGSSMKSVGEVMAIGRSFEEAFQKALRMVDENCVGFDHTIKPESEE----ELQTPTDKRIFVLAAALHAG-YTVERLYELTKIDHWFLHKMKNIADHKKLLETYKQDESAMPPEIMRKAKQLGFSDKQIAQAVQSTELAVRKLRRDWKIFPVVKQIDTVAAEWPAQTNYLYLTYHGSESDVVFEQPHVMVIGSGVYRIGSSVEFDWCAVGCIMELRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYEMENPEGVILSMGGQLPNNIAMSLHRQQCRILGTSPEFIDNAENRFKFSRMLDTIGISQPRWKELSDTESAVNFCETVGYPCLVRPSYVLSGAAMNVAYSDTDMEKFLSSAVAVSKEHPVVISKFIQEAKEIDVDAVACDGEVIAIAVSEHVENAGVHSGDATLVTPPQDINQKTMERIKMIVHAIGQELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPYVSKTLGVDLVALATRVILGEEVEAVGLMRG-NGIVGVKVPQFSFSRLAGADVVLGVEMTSTGEVACFGENRYEAYLKAMLSTGFKIPKKNILLSIGSYKNKSELLPTVQTLESLGYNLYASLGTADFYTEHGVKVMAVDWPFEEESD--CPNKDKQRNIMDYLEENHFDLVINLSMRNSGGRRLSSFVTKGYRTRRMAIDFSVPLITDIKCTKLFVQALKQIGQAPRVKTHVDSMTSQKLIRLPGLIDVHVHLREPGATHK--EDFSSGTAAALAGGITMVCAMPN--TNPAIIDPNSFTMAQKLAKAGCRCDYALFVGASSDNAALLPSIASSTAGLKMYLNDTYSTLKMDNVSLWMEHFEKWPKHLPIVAHAEKQTVAAILLVAQLYQRPVHICHVAKKEEILIIRAAKQKGIQVTCEVAPHHLFLCEDNVPVIGKDKAQVRPMLGTREDMEALWENLDIIDCFATDHAPHSAEEKISEKPPPGYPGLETMLPLLFTAVSEGRLTVDDIIKRLYENPRKIFSLPAQEDTYVEVDLEQEWIIPKHMQFTKSKWTPFEGMKVKGKVMRVVLRGEVAYIDGQVLVPPGYGQDVKSWSATPTATTEVIMDAPKRVIEAMTPERPRQAAPVDVVRSRAPSPRRSAGDGRFILPPRIHRSSDPGLPPGFKR-----STMHPQKAFAEEEVSLRAPFDAELALPAEAYAHP-PPLARILSPQAGQPQILPHPQTSPLLHPLVGQHILSVRQFSKEQMSHLFNVAHTLRLMVQKERPLDILK-GKVMASMFYEVSTRTSSSFAAAMHRLGGSVVHFCESTSSTQKGESLVDSVNTMSCYADVIVLRHPIPGAVESAARHCRRPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLARLLTQYRITLRYVAPKNLSMPAEIIDFVASKGIK-QEEFNSIEEALPDTDVLYMTRIQKERFSSEKEYNACFGQFILTPHIMTGAKRKMVVMHPLPRVNEISVEVDTDPRAAYFRQAENGMYIRMALLATVLGR-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P05990-1", "uniprot_id": "PYR1_DROME", "id": "P05990-1", "name": "Multifunctional protein r", "aln": "---------------------------------------------------------------------------MASTDCYLALEDGTVLPGYSFGYVPSENESKVGFGGEVVFQTGMVGYTEALTDRSYSGQILVLTYPLIGNYGVP---APDEDEHGLPLHFEWMKGVVQATALVVGEVAEEAFHWRKWKTLPDWLKQHKVPGIQDIDTRALTKKLREQGSMLGKIVYEKPPVE-----------GLPKSSFVDPNVRNLAKECSVKERQVYGNPN------------GKGPRIAILDCGLKLNQLRCLLQRGASVTLLPWSARLEDEQFDALFLSNGPGNPESCDQIVQQVRKVIEE-GQKPVFGICLGHQLLAKAIGCSTYKMKYGNRGHNLPCLHRATGRCLMTSQNHGYAVDLEQLPDGWSELFVNANDGTNEGIVHASKPYFSVQFHPEHHAGPQDTEFLFDVFMESIQ------QKDLTIPQLIEQRLR-PTTPAIDSAPVMPRKVLILGSGGLSIGQAGEFDYSGSQAIKAMRESNIQTVLINPNIATVQTSKGMADKCYFLPLTPHYVEQVIKSERPNGVLLTFGGQTALNCGVQLERAGVFSKYNVRILGTPIQSIIETEDRKLFAERVNEIGEQVAPSEAVYSVAQALDAASRLGYPVMARAAFSLGGLGSGFANNEEELQSLAQQALAHSSQLIVDKSLKGWKEVEYEVVRDAYNNCITVCNMENFDPLGIHTGESIVVAPSQTLSDREYQMLRSTALKVIRHFGVVGECNIQYALCPHSEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGLPLPDIKNSVTGNTTACFEPSLDYCVVKIPRWDLAKFVRVSKHIGSSMKSVGEVMAIGRNFEEAFQKALRMVDSDVLGFDPDVVPLNKEQLAEQLSEPTDRRPFVIAAALQLG-MSLRELHQLTNIDYWFLEKLERIILLQSLLTRNGS---RTDAALLLKAKRFGFSDKQIAKYIKSTELAVRHQRQEFGIRPHVKQIDTVAGEWPASTNYLYHTYNGSEHDVDFPGGHTIVVGSGVYRIGSSVEFDWCAVGCLRELRKLQRPTIMINYNPETVSTDYDMCDRLYFEEISFEVVMDIYEMENSEGIILSMGGQLPNNIAMDLHRQQAKVLGTSPESIDCAENRFKFSRMLDRKGILQPRWKELTNLQSAIEFCEEVGYPCLVRPSYVLSGAAMNVAYSNQDLETYLNAASEVSREHPVVISKFLTEAKEIDVDAVASDGRILCMAVSEHVENAGVHSGDATLVTPPQDLNAETLEAIKRITCDLASVLDVTGPFNMQLIAKNNELKVIECNVRVSRSFPFVSKTLDHDFVATATRAIVGLDVEPLDVLHG-VGKVGVKVPQFSFSRLAGADVQLGVEMASTGEVACFGDNRYEAYLKAMMSTGFQIPKNAVLLSIGSFKHKMELLPSIRDLAKMGYKLYASMGTGDFYAEHGVNVESVQWTFDKTTPDDING--ELRHLAEFLANKQFDLVINLPMSGGGARRVSSFMTHGYRTRRLAVDYSIPLVTDVKCTKLLVESMRMNGGKPPMKTHTDCMTSRRIVKLPGFIDVHVHLREPGATHK--EDFASGTAAALAGGVTLVCAMPN--TNPSIVDRETFTQFQELAKAGARCDYALYVGASDDNWAQVNELASHACGLKMYLNDTFGTLKLSDMTSWQRHLSHWPKRSPIVCHAERQSTAAVIMLAHLLDRSVHICHVARKEEIQLIRSAKEKGVKVTCEVCPHHLFLSTKDVERLGHGMSEVRPLLCSPEDQEALWENIDYIDVFATDHAPHTLAEKRSERPPPGFPGVETILPLLLQAVHEGRLTMEDIKRKFHRNPKIIFNLPDQAQTYVEVDLDEEWTITGNEMKSKSGWTPFEGTKVKGRVHRVVLRGEVAFVDGQVLVQPGFGQNVRPKQSP-LASEASQDLLPSDNDANDTFTRLLTSEGP--------------GGGVHGISTKVHFVDGANFLR-------------------PNSPSPRIRLD-------------------SASNTTLREYLQRTTNSNPVAHSLMGKHILAVDMFNKDHLNDIFNLAQLLKLRGTKDRPVDELLPGKIMASVFYEVSTRTQCSFAAAMLRLGGRVISMDNITSSVKKGESLEDSIKVVSSYADVVVLRHPSPGAVARAATFSRKPLINAGDGVGEHPTQALLDIFTIREEFGTVNGLTITMVGDLKNGRTVHSLARLLTLYNVNLQYVAPNSLQMPDEVVQFVHQRGVK-QLFARDLKNVLPDTDVLYMTRIQRERFDNVEDYEKCCGHLVLTPEHMMRAKKRSIVLHPLPRLNEISREIDSDPRAAYFRQAEYGMYIRMALLAMVVGGRNTAL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07259-1", "uniprot_id": "PYR1_YEAST", "id": "P07259-1", "name": "Multifunctional protein URA2", "aln": "-----------------------------------------------------------MATIAPTAPITPPMESTGDRLVTLELKDGTVLQGYSFGAEKS-------VAGELVFQTGMVGYPESVTDPSYEGQILVITYPLVGNYGVPDMHLRDELVEELPRYFESNR--IHIAGLVISHYTDEYSHYLAKSSLGKWLQNEGIPAVYGVDTRSLTKHLRDAGSMLGRLSLEKSGSDRTISRSSSWRSAFDVPEWVDPNVQNLVSKVSINEPKLYVPPADNKHIELQTGPDGKVLRILAIDVGMKYNQIRCFIKRGVELKVVPWNYDFTKEDYDGLFISNGPGDPSVLDDLSQRLSNVLEA-KKTPVFGICLGHQLIARAAGASTLKLKFGNRGHNIPCTSTISGRCYITSQNHGFAVDVDTLTSGWKPLFVNANDDSNEGIYHSELPYFSVQFHPESTPGPRDTEFLFDVFIQAVK-----EFKYTQVLKPIAFPGGLLEDNVKAHPRIEAKKVLVLGSGGLSIGQAGEFDYSGSQAIKALKEEGIYTILINPNIATIQTSKGLADKVYFVPVTAEFVRKVILHERPDAIYVTFGGQTALSVGIAMK--DEFEALGVKVLGTPIDTIITTEDRELFSNAIDEINEKCAKSQAANSVDEALAAVKEIGFPVIVRAAYALGGLGSGFANNEKELVDLCNVAFSSSPQVLVEKSMKGWKEVEYEVVRDAFDNCITVCNMENFDPLGIHTGDSIVVAPSQTLSDEDYNMLRTTAVNVIRHLGVVGECNIQYALNPVSKDYCIIEVNARLSRSSALASKATGYPLAYTAAKLGLNIPLNEVKNSVTKSTCACFEPSLDYCVVKMPRWDLKKFTRVSTELSSSMKSVGEVMSIGRTFEEAIQKAIRSTEYANLGFNETDLDIDID---YELNNPTDMRVFAIANAFAKKGYSVDKVWEMTRIDKWFLNKLHDLVQFAEKISSFGT-KEELPSLVLRQAKQLGFDDRQIARFLDSNEVAIRRLRKEYGITPFVKQIDTVAAEFPAYTNYLYMTYNADSHDLSFDDHGVMVLGSGVYRIGSSVEFDWCAVTAVRTLRANNIKTIMVNYNPETVSTDYDEADRLYFETINLERVLDIYEIENSSGVVVSMGGQTSNNIAMTLHRENVKILGTSPDMIDSAENRYKFSRMLDQIGVDQPAWKELTSMDEAESFAEKVGYPVLVRPSYVLSGAAMNTVYSKNDLESYLNQAVEVSRDYPVVITKYIENAKEIEMDAVARNGELVMHVVSEHVENAGVHSGDATLIVPPQDLAPETVDRIVVATAKIGKALKITGPYNIQFIAKDNEIKVIECNVRASRSFPFISKVVGVNLIELATKAIMGLPLTPYPVEKLPDDYVAVKVPQFSFPRLAGADPVLGVEMASTGEVATFGHSKYEAYLKSLLATGFKLPKKNILLSIGSYKEKQELLSSVQKLYNMGYKLFATSGTADFLSEHGIAVQYLEVLNKDDDDQKSE-----YSLTQHLANNEIDLYINLPSAN-RFRRPASYVSKGYKTRRLAVDYSVPLVTNVKCAKLLIEAISRN--ITLDVSERDAQTSHRTITLPGLINIATYVPNASHVIKGPAELKETTRLFLESGFTYCQLMPRSISGPVITDVASLKAANSVSQDSSYTDFSFTIAGTAHNAHSVTQSASKVTALFLPLRELK-----NKITAVAELLNQWPTEKQVIAEAKTADLASVLLLTSLQNRSIHITGVSNKEDLALIMTVKAKDPRVTCDVNIYSLFIAQDDYP--------EAVFLPTKEDQEFFWNNLDSIDAFSVGALPVALANVTGNKVDVGMG-IKDSLPLLLAAVEEGKLTIDDIVLRLHDNPAKIFNIPTQ-DSVVEIDLDYSFRR-------NKRWSPFN-KDMNGGIERVVYNGETLVLSGELVSPGAKGKCIVNPSPASITASAELQSTSAKRRFSITEEAIADNLDA-------------AEDAIPEQPLEQKLMS---------------------------SRPPR----------------------ELVAPGAIQNLIRSN-------NPFRGRHILSIKQFKRSDFHVLFAVAQELRAAVAREGVLDLMK-GHVITTIFFEPSTRTCSSFIAAMERLGGRIVNVNPLVSSVKKGETLQDTIRTLACYSDAIVMRHSEEMSVHIAAKYSPVPIINGGNGSREHPTQAFLDLFTIREEIGTVNGITVTFMGDLKHGRTVHSLCRLLMHYQVRINLVSPPELRLPEGLREELRKAGLLGVESIELTPHIISKTDVLYCTRVQEERFNSPEEYARLKDTYIVDNKILAHAKENMAIMHPLPRVNEIKEEVDYDHRAAYFRQMKYGLFVRMALLAMVMGVDM---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:**:.: * ** * .**:*********.*::** **..***.:***::****:* : * ** :: :.*::.. *: :* .**::. :*.: .:*** ***::*: *::**:: : . . : : :*:.: *. : *:: ::: ** :* *:* **:**: : *. :.::**. : ...::.**:*****:* . : .* *:*********:: . *..* *:::****** ** :.** :******:**: : *. .* **.**** :.*** * * ******** .** * ***:*::::: : : : .:***:************************::*..* *:********:***:*:*** **:*:* .:* :** ***:.: :********. *: : . : *::****: :* ****. * : **.*: * *:*. *: :* *...:*:**:.*:*::*********....*: * *:: :.*::::**:*****:********:.**:*******:********:**********.* :*::** **::* :*:*:*****:**** * *::* *************************.****.*.:** ::**** . * ****:******:***** ** ***..:.*.********.***.****:***:* .: :**: . :*. *** * *.:* *: :: .: ::*.** ***.::. : . : :: :** :**.*:*** : *.*:.:*: *:: * * ********.*:** ***** ** . *: * .:*:****************** .: ** ***:************ .*****: *.:* *:****:**..*:::***** .**:** ***:: ::*****: ** ****:****:** *: ** *:**:. :.* .*.. **** :*************..*:. *:* :*. * **:::****:*:: :****::**** :* : .:****************:.****: :*:: * . :.. *.:***:*:*:***::::********.*****::**.:. ::: **: *:* : . : . *.********.****** *****:****** **..: *****::::***::*:: :**:***:*.* ***.::: * .:**.*:*: **.** :***: * :: .. : : * ::.::* ***. . ** :*::::**:***:* *:*:**: ::**:**::::: . . *. **:: : ***:*:: .:: :.. . * :: . * * .*.* **. : * * * :: :.::: .. *::: :..: .* : *. . .* : *.: ..: . :. ** . ::..*: *:::::: * *.:** *:.**:: :* :.* :. ***:* : **: .: * : :* * :*:*: ** *: . * : : . : * :: ****: ** **:*:::*: ::: ** ** :* * :: **:**: .: : *:**: .::* : *** .**. :.*::: . *: : . . * .. . . : . . . * : :.: *:***:: *.:..: :* :*: *: :: :* : *::::::*:* **** .** *** **** :: . .**.:***:* *::..::.*:*.:*:**. :* ** .. *:**.*:* ******:**:******:*****:*:*::****:*******. ** *.: :. *:* .* :* : : . * . . :..***** **:*.***.. ::* . :: . : **.. ::**:**:***. *:* * ******* : *:::****** *:* ", "identical_positions": 896, "similar_positions": 640, "identity": "37.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021030-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y176-1", "uniprot_id": "A0A8I5Y176_RAT", "id": "A0A8I5Y176-1", "name": "", "aln": "-----MSGQPPPPPPQQQ------PPPPPAAGAPGSGVALPAPAAASAGSSPAGSPGG-----GLGAAAAALLLHPPPPPP----------------PPPATAAPPPPASAAAPAT---APPGLA-----VGP---------GSVAGVPVPGLAAGSSAAAPFPHGDS--------------------------------------------------------------------------------ALNEQE------------------------------------------------------------------------------------------------KELQRR--------------------------------------------------------LKRLYPAVDEQETPLPRSWSPKDKFSYIGLSQNNLRVHYKGHGKTPKDAASVRATHPIP---AACGIYYFEVKIVSKGRDGYMGIG-LSAQGVNMN------RLPGWDKHSYGYHGDDGHSFCSSGTGQPYGPTFTTGDVIGCCVNLINNTCFYTKNGHSLGIAFTDLPPNLYPTVGLQTPGEVVDANFGQ-HPFVFD-IEDYMREWRTKIQAQIDRFPIGDREGEWQTMIQKMVSSYLVHHGYCATAEAFARSTDQTVLEELASIKNRQRIQKLVLAGRMGEAIETTQQLYPSLLERNPNLLFTLKVRQFIEMVNGTDSEVRCLGGRSPKSQDSYPVSPRPFSSPSMSPSHGMSIHSLAPGKGSTAHFPGFES-CSNGVISNKAHQSYCHS-KHQLSSLNVPELNSINVSRSQQVNNFTSNDVDMETDHYSNGVGETSSNGFLNGSSKHDHEMEDCDTEMEVDCSQLRRQLCGGSQAAIERMIHFGRELQAMSEQLRRECGKNTANKKMLKDAFSLLAYSDPWNSPVGNQLDPIQREPVCSALNSAILETHNLPKQPPLALAMGQATQCLGLMARAGVGSCAFATVEDYLH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P69566-1", "uniprot_id": "RANB9_MOUSE", "id": "P69566-1", "name": "Ran-binding protein 9", "aln": "-----MSGQPPPPPPQQQ------PPPP-----------------------------------------------------------------------------PPPASAAAPAT---APPGLA-----VGP---------GPAAGVPVPGLAAGSSAAAPFPHGDS--------------------------------------------------------------------------------ALNEQE------------------------------------------------------------------------------------------------KELQRR--------------------------------------------------------LKRLYPAVDEQETPLPRSWSPKDKFSYIGLSQNNLRVHYKGHGKTPKDAASVRATHPIP---AACGIYYFEVKIVSKGRDGYMGIG-LSAQGVNMN------RLPGWDKHSYGYHGDDGHSFCSSGTGQPYGPTFTTGDVIGCCVNLINNTCFYTKNGHSLGIAFTDLPPNLYPTVGLQTPGEVVDANFGQ-HPFVFD-IEDYMREWRTKIQAQIDRFPIGDREGEWQTMIQKMVSSYLVHHGYCATAEAFARSTDQTVLEELASIKNRQRIQKLVLAGRMGEAIETTQQLYPSLLERNPNLLFTLKVRQFIEMVNGTDSEVRCLGGRSPKSQDSYPVSPRPFSSPSMSPSHGMSIHSLAPGKSSTAHFSGFES-CSNGVISNKAHQSYCHS-KHQLSSLTVPELNSLNVSRSQQVNNFTSNDVDMETDHYSNGVGETSSNGFLNGSSKHDHEMEDCDTEMEVDCSQLRRQLCGGSQAAIERMIHFGRELQAMSEQLRRECGKNTANKKMLKDAFSLLAYSDPWNSPVGNQLDPIQREPVCSALNSAILETHNLPKQPPLALAMGQATQCLGLMARSGVGSCAFATVEDYLH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96S59-1", "uniprot_id": "RANB9_HUMAN", "id": "Q96S59-1", "name": "Ran-binding protein 9", "aln": "-----MSGQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAA-----------PPPPPPPPPPPASAAAPASGPPAPPGLA-----AGP---------GPAGGAPTPALVAGSSAAAPFPHGDS--------------------------------------------------------------------------------ALNEQE------------------------------------------------------------------------------------------------KELQRR--------------------------------------------------------LKRLYPAVDEQETPLPRSWSPKDKFSYIGLSQNNLRVHYKGHGKTPKDAASVRATHPIP---AACGIYYFEVKIVSKGRDGYMGIG-LSAQGVNMN------RLPGWDKHSYGYHGDDGHSFCSSGTGQPYGPTFTTGDVIGCCVNLINNTCFYTKNGHSLGIAFTDLPPNLYPTVGLQTPGEVVDANFGQ-HPFVFD-IEDYMREWRTKIQAQIDRFPIGDREGEWQTMIQKMVSSYLVHHGYCATAEAFARSTDQTVLEELASIKNRQRIQKLVLAGRMGEAIETTQQLYPSLLERNPNLLFTLKVRQFIEMVNGTDSEVRCLGGRSPKSQDSYPVSPRPFSSPSMSPSHGMNIHNLASGKGSTAHFSGFES-CSNGVISNKAHQSYCHSNKHQSSNLNVPELNSINMSRSQQVNNFTSNDVDMETDHYSNGVGETSSNGFLNGSSKHDHEMEDCDTEMEVDSSQLRRQLCGGSQAAIERMIHFGRELQAMSEQLRRDCGKNTANKKMLKDAFSLLAYSDPWNSPVGNQLDPIQREPVCSALNSAILETHNLPKQPPLALAMGQATQCLGLMARSGIGSCAFATVEDYLH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L252-1", "uniprot_id": "RANB9_DANRE", "id": "A1L252-1", "name": "Ran-binding protein 9", "aln": "----------------------------------------------------------------------------------------------------------------------------M-----SGP---------SSGCGFLMS----------VVVHGDL--------------------------------------------------------------------------------ALNEQE------------------------------------------------------------------------------------------------KELNQR--------------------------------------------------------LRRLYPAVNEQETPLPRSWSPKDKFSYIGLSQNNLRVHYKGHGKTPKDAASVRATHPIP---AACGVYYFEVKIISKGRDGYMGIG-LSAQGVNMN------RLPGWDKHSYGYHGDDGHSFCSSGTGQPYGPTFTTGDVIGCCVNLINNTCFYTKNGHSLGIAFTDLPPNLYPTVGLQTPGEVVDANFGQ-HPFVFD-IEDYMREWRTKIQSQIDRFPIGEREGEWQAMIQKMVASYLVHHSYCATAEAFAKSTDQAVHEELASIKNRQKIQKLVLSGRMGEAIETTQQLYPSLLERNPDLLFMLKVRQFIEMVNGTDSEVRCLGGRSPKSQDSYPGSPRLFNSPVHKPSS------------SQAYQTGFDSNYCNGVSSSKGHTS-AHSHKSCPPTLSSPELGVLNGSRGQQT--IVSSEVEMEVDHFSNGVSESSSNGFLNGSSTHGTEQEDCDADMEVDSTQSKRQLCGGSQAAIERMIQFGRELQSMSEHLRRERGKNSANKKMLKDAFSLLAYSDPWNSPVGYQLDSIQREPVCSTLNSAILETHNLPKQPPLALAMGQAAQCLSLMARTGSGSCAFASVDDYLH--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q4Z8K6-1", "uniprot_id": "RBP9X_DROME", "id": "Q4Z8K6-1", "name": "Ran-binding proteins 9/10 homolog", "aln": "----MENVEEAPPLSSESNSNSNNSSASSSSHQLSQSGAMGAEIAPSTSRSHSHSPTPSPPVPASSHDQPHPDHPSPPLNASETEARENSPHDHSPTPTFHQTAPPPTTSSTAPQRDEREQQQQQ-----EAPPLQQDQQENSPAQDQELHPLLDQQNQEYPAVHQDQQAEQNQELHHIEGLIRHRESQNPEEHPPQASLENRETLGREDTNQEPDEPQVRDPEIEPEAEPPPPLLLEDLDEQDSGSQDLNEQQPPLIIDANAIAETIDANAVERIDDYEDDDEEVDEEEEVVEDRVDRAGEVASVSGAQRLHSVAVLPRYSSASRAPRSSNNNNNNISNHNNNNNNSNSNSLSRRTRHFYSNNGSHFSNDMFPSHNPRSSTQTSSPRVGGRRHHSTPAASSNSPQHQGVDPLRLLYPNVNESETPLPRCWSPHDKCLSIGLSQNNLRVTYKGVGKQHSDAASVRTAYPIP---SSCGLYYFEVRIISKGRNGYMGIG-LTAQQFRMN------RLPGWDKQSYGYHGDDGNSFSSSGNGQTYGPTFTTGDVIGCCVNFVNNTCFYTKNGVDLGIAFRDLPTKLYPTVGLQTPGEEVDANFGQ-EPFKFDKIVDMMKEMRSNVLRKIDRYPHLLETP--ENLMNRLVSTYLVHNAFSKTAEAFNGYTNQTFNEDLASIKTRQKIIKLILTGKMSQAIEHTLRSFPGLLENNKNLWFALKCRQFIEMINGADIEN--VNNKVTATTQTMPTNQTSVIQSTKTFKH-------------SKSGSGNGNVNINQTQQQNNTAIPAVIKPQGGDRPDIKNMLVDDNSNKCVEHDSNSMDVEMEPCQSHSNGGDSSSNG---NASAVRNSLDAIDEEMDVDVSPSSR-NCG---RVIEKILEFGKELSSMGQQLEKENLMTEEERQMLEDAFSLIAYSNPWSSPLGWLLCPSRRESVSTTLNSAILESLNFERRPPLEYLVAHASELIKVIGQHSLGEDAFITIDDVFPQN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53076-1", "uniprot_id": "VID30_YEAST", "id": "P53076-1", "name": "GID complex subunit 1", "aln": "MSEYMDDVDREFINCLFPSYLLQQPVAYDLWILYLQHRKLFHKLKNTNLINADENPTGVGMGRTKLTALTRKEIWSKLMNLGVLGTISFEAVNDDYLIQVYKYFYPDVNDFTLRFGVKDSNKNSVRVMKASSDMRKNAQELLEPVLSEREMALNSNTSLENDRNDDDDDDDDDDDDDDDDDDDDDESDLESLEGEVDTDTDDNNEGDGSDNHEEGGEEGSRGADADVSSAQQRAERVADPWIYQRSRSAINIETE--------------SRNLWDTSDKNSGLQYYPPDQSPSSSFSSPRVSSGNDKNDNEATNVLSNSGSKKKNSMIPDIYKILGYFLPSRWQAQPNNSLQLSQDGITHLQPNPDYHSYMTYERSSASSASTRNRLRTSFENSGKVDFAVTWANKSLPDNKLTIFYYEIKVLSVTSTESAENSNIVIGYKLVENELMEATTKKSVSRSSVAGSSSSLGGSNNMSSNRVPSTSFTMEGTQRRDYIYEGGVSAMSLNVDGSINKCQKYGFDLNVFGYCGFDGLITNSTEQSKEYAKPFGRDDVIGCGINFIDGSIFFTKNGIHLGNAFTDLNDLEFVPYVALRPGNSIKTNFGLNEDFVFD-IIGYQDKWKSLAYEHICRG---------RQMDVSIEEFDSDESEEDETENGPEENKSTNVNEDLMDIDQEDGAAGNKDTKKLNDEKDNNLKF---LLGEDNRFIDGKLVRPDVNNINNLSVDDGSLPNTLNVMINDYLIHEGLVDVAKGFLKD-------------LQKDAVNVNGQHSESKDVIRHNERQIMKEERMVKIRQELRYLINKGQISKCINYIDNEIPDLLKNNLELVFELKLANYLVMIKKSSSKDDDEIENLILKGQELSNEFIYDTKIPQSLRDRFSGQLSNVSALLAYSNPLVEAPKEISGYLSDEYLQERLFQVSNNTILTFLHKDSECALENVISNTRAMLSTLLEYNAFGSTNSSDPRYYKAINFDEDVLNL--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . * :* : .*.: * :* :. ... ... . : * :*:* . . ...*. :: . :: : .. : .. * .*: * ::* ..:: : *:* : :** * ** *: .: *. .* .***** :*:::.: *:**** ** ** ** : . **: :.:*** . * ** * . : :: :* * . : : . * :. .. . *:* .*. .: : ::.: : . : ** .: : * :: :*. . : : . : . . . . . . . : .. . :: : . : . . . . : :: :. . . .*. :*. :. * . ::: . . :. . . * :::. .: * : . :. . .. .: ", "identical_positions": 64, "similar_positions": 168, "identity": "6.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021031-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97603-1", "uniprot_id": "NEO1_RAT", "id": "P97603-1", "name": "Neogenin", "aln": "------------------------------------------AAAKNGSPPQSAGASVRTFTPLYFLVEPVDTLSVRGSSVILNCS------------AYSEPSPNIEWK-KDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGFYQCVATVDNLGTIVSRTAKLAVAGLPRFTSQPEPSSIYVGNSGILNCEVNAD-----LVPFVRWEQNRQPLLLDDR-IVKLPSGTLVISNATEGDEGLYRCIVESGGPPKFSDEAELKVLQES----EEMLDLVFLMRPSSMIKVIGQSAVLPCVASGLPAPVIRWMKNEDVLDT-ESSGRLALLAGGSLEISDVTEDDAGTYFCVADNGNKTIEAQAELTVQVPPEFLKQPANIYARESMDIVFECEVTGKPAPTVKWVKNGDVVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEH----------------------------------------------------------------------------------------------------------------------------------------------------------------------APATTG---PLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGVARERVENTSQPGEMQVTIQNLMPATVYIFKVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNIRAYATSPTSITVTWETPLSGNGEIQNYKLYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTQDVAVRTLSDVPSAAPQNLSLEVRNSKSIVIHWQPPSSATQNGQITGYKIRYRKASRKSDVTETVVTGTQLSQLIEGLDRGTEYNFRVAALTVNGTGPATDWLSAETFESDLDESRVPEVPSSLHVRPLVTSIVVSWTPPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTD--TSEVDLFVIN-APYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGATFELVPTSPPKDVTVVSKEGKPRTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMG--PMSEAVQFRTPKADSSDKMPNDQALGSAGKGGR--LPD--LGSDYKPPMSGSNSPHGSPTSPLDSNMLLVIIVSIGVITIVVVVIIAVFCTRRTTSHQKKKRAACKSVNGSHKYKGNCKDVKPPDLWIHHERLELKPIDKSPDPNPVMTDTPIPRNSQDITPVDNSMDSNIHQRRNSYRGHESEDSMSTLAGRRGMRPKMMMPFDSQPPQ-----------------------------------------------------QSVRNTPSTDTMPASSSQTCCTDHQDPEGATSSSYLASSQEEDSGQSLPTAHVRPSHPLKSFAVPAIPPPGPPIYD-PALPSTPLLSQQALNHHLHSVKTASIGTLGRSRPPMPVVVPSAPEVQEATRMLEDSESSYEPDELTKEMAHLEGLMKDLNAITTA----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97798-1", "uniprot_id": "NEO1_MOUSE", "id": "P97798-1", "name": "Neogenin", "aln": "MAAEREAGRLLCTSSSRRCCPPPPLLLLLPLLLLLGRPASGAAATKSGSPPQSAGASVRTFTPFYFLVEPVDTLSVRGSSVILNCS------------AYSEPSPNIEWK-KDGTFLNLESDDRRQLLPDGSLFISNVVHSKHNKPDEGFYQCVATVDNLGTIVSRTAKLTVAGLPRFTSQPEPSSVYVGNSAILNCEVNAD-----LVPFVRWEQNRQPLLLDDR-IVKLPSGTLVISNATEGDGGLYRCIVESGGPPKFSDEAELKVLQDP----EEIVDLVFLMRPSSMMKVTGQSAVLPCVVSGLPAPVVRWMKNEEVLDT-ESSGRLVLLAGGCLEISDVTEDDAGTYFCIADNGNKTVEAQAELTVQVPPGFLKQPANIYAHESMDIVFECEVTGKPTPTVKWVKNGDVVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHDVAIPTLP--------------------------------------------------------------------------------------------------------------------------------------------------PTSLTSATTDHLAPATTG---PLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGVARERVENTSQPGEMQVTIQNLMPATVYIFKVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNIRAYATSPTSITVTWETPLSGNGEIQNYKLYYMEKGTDKEQDIDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTQDVAVRTLSDVPSAAPQNLSLEVRNSKSIVIHWQPPSSTTQNGQITGYKIRYRKASRKSDVTETLVTGTQLSQLIEGLDRGTEYNFRVAALTVNGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSWTPPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTD--TSEVDLFVIN-APYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGATFELVPTSPPKDVTVVSKEGKPRTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMG--PMSEAVQFRTPKADSSDKMPNDQALGSAGKGSR--LPD--LGSDYKPPMSGSNSPHGSPTSPLDSNMLLVIIVSVGVITIVVVVVIAVFCTRRTTSHQKKKRAACKSVNGSHKYKGNCKDVKPPDLWIHHERLELKPIDKSPDPNPVMTDTPIPRNSQDITPVDNSMDSNIHQRRNSYRGHESEDSMSTLAGRRGMRPKMMMPFDSQPPQPVISAHPIHSLDNPHHHFHSSSLASPARSHLYHPSSPWPIGTSMSLSDRANSTESVRNTPSTDTMPASSSQTCCTDHQDPEGATSSSYLASSQEEDSGQSLPTAHVRPSHPLKSFAVPAIPPPGPPLYD-PALPSTPLLSQQALNHHIHSVKTASIGTLGRSRPPMPVVVPSAPEVQETTRMLEDSESSYEPDELTKEMAHLEGLMKDLNAITTA----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92859-1", "uniprot_id": "NEO1_HUMAN", "id": "Q92859-1", "name": "Neogenin", "aln": "MAAERGARRLLSTPS-----------FWLYCLLLLGRRAPGAAAARSGSAPQSPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCS------------AYSEPSPKIEWK-KDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNNAILNCEVNAD-----LVPFVRWEQNRQPLLLDDR-VIKLPSGMLVISNATEGDGGLYRCVVESGGPPKYSDEVELKVLPDP----EVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDT-ESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEH----------------------------------------------------------------------------------------------------------------------------------------------------------------------APATTG---PLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPTSITVTWETPVSGNGEIQNYKLYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRYRKASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSWTPPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTD--TSEVDLFVIN-APYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGKPKTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMG--PMSEAVQFRTPKADSSDKMPNDQASGSGGKGSR--LPD--LGSDYKPPMSGSNSPHGSPTSPLDSNMLLVIIVSVGVITIVVVVIIAVFCTRRTTSHQKKKRAACKSVNGSHKYKGNSKDVKPPDLWIHHERLELKPIDKSPDPNPIMTDTPIPRNSQDITPVDNSMDSNIHQRRNSYRGHESEDSMSTLAGRRGMRPKMMMPFDSQPPQPVISAHPIHSLDNPHHHFHSSSLASPARSHLYHPGSPWPIGTSMSLSDRANSTESVRNTPSTDTMPASSSQTCCTDHQDPEGATSSSYLASSQEEDSGQSLPTAHVRPSHPLKSFAVPAIPPPGPPTYD-PALPSTPLLSQQALNHHIHSVKTASIGTLGRSRPPMPVVVPSAPEVQETTRMLEDSESSYEPDELTKEMAHLEGLMKDLNAITTA----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AUL1-1", "uniprot_id": "A0A8M3AUL1_DANRE", "id": "A0A8M3AUL1-1", "name": "Neogenin", "aln": "-MAERGAR------------------------LLLS-----LFCLTITVSHAEKGSAVRNFSPFWFSTEPSDTLAVRGAPVLLNCS------------VHSESPAKIEWK-KDGSFLSLASDERRQVLADGSLLISSVVHSKHNKPDEGVYQCVATIDNLGTIISRTARLNVAGIARFLSQPEMASVRVGDSQVLSCEVNPD-----LVSFIRWEQNKEAVELDHR-VFSLPSGALVISNATETDAGLYRCVIDNAGPTKTSEEAQLHILTET----GEERTLEFLQEPQHVSKLVGESVLLPCVVTGYPTPEITWMYKDQLIE--DSSGRFEILGGGSLRIFNLTEEDAGVYNCLAENTNGSIEAQAELTLKDSPQFLKKPVNVFAHEATDVIFECEVSGSPSPTIKWVKNGDAVIPSDYFKIIKEQNLQVLGLVKSDEGFYQCLAENDAGNVQSSAQLVILDQDVTLPLPR--------------------------------------------------------------------------------------------------------------------------------------------------PTSLTRATTDRLMPGSRGGAGPTPSAPRDVVASLVSTRFLKLTWRLPA-EPHGDDVTYSVYYSLEGTNRERIVNTSRPGEMQVTIQNLMPDTKYAFRVVAHNKNGPGESSVPLKVETQPEVQVPGPAPNLHAVVMSPSTVSLSWDVPLIGNGEIQNYKIYYMEKGMDSEQDLDVNTLSYTMTGLKKFTEYSFRLVAYNKHGPGVSTEDISVRTYSDVPSSPPQNMTVEVLNSKSLMIRWQPPPADAQNGEITGYKIRYRKGTRKSEVAE-ITSGSQLYQLIDGLQRGTEYMLRVSAMTVNGTGPATDWTTAETFESDLDESRVPDVPSSLHVRSLVNSIVVSWTPPENQDIVVRGYSISYGIGSPHAQTIKVDYKQRYYTIENLNPNSHYVITLKAFNNVGEGIPVYESAITRPQSDPIDPDVDLYELFHAPYTPVPDPIPMLPPVGVQASVLNQDTIKVTWADNSLPKNQKITDARYYTVRWKTNIPANTKFKVANTTTLFHTVTGLKPNTLYEFSVMVTKGRRTSTWSMTAHGTTFESIPSSPPKDVTVVSKEGRPKTIIVNWQPPSEANGKITGYIIYYSTDVKAEVHDWVIEPVVGNRLTHQIQELTLDTTYYFKIQARNSKGMG--PMSEAVQFRTPKAESSDKMANDQAPGISVKQGRPSAPDNGFGSPGKPDMSGTGDNH---------ILVIVIIVSVGAFTIIVVVVGAFLCTRRTTTQQKKKRAACKSANGSHKYKGNSKDLKPPDLWIHHERLELKPIDKSPEPNPVMTDTPIPRTSQDITPVDGSMDP-MLQRRNSYRGHESEDSMSTLAGRRGMRPKMMMPFDAQPPQPVISAHPIHSLDNHHHHYHLGSLASPTRSYLHHQSSTRSIATPISHLDRAESTESVRNTPNAELLPPSGQPSCTTDLS----ETDISFHSSAAEEEPAFATPTAHVRPTHPLKSFAVPAIP--AHAMYDSAALPSTPLLSQTGP----HSVKTASIGTLGRTRTPMPVIVPNAPDVSEGCRLHEDAGSNYETDELSEEMAHLEGLMKDLNAITTA----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z920-1", "uniprot_id": "A1Z920_DROME", "id": "A1Z920-1", "name": "", "aln": "-----------------------------MAITTNRSSRTLWNWLLSSCLIFQLIGSSLASQALSFTLEPQDAVVPEGHSVLLQCAGTASIGRGGKSKSNLPSSVSIRWRGPDGQDLVIVGDTFRTQLKNGSLYISSVEE---NRGLTGAYQCLLTAEGVGSILSRPALVAIVRQPDLNQDFLETYLLPGQTAYFRCMLGEANWQEGVKHSVQWLKDDLPLPLDKLRMVVLPNGALEIDEVGPSDRGSYQCNVTSGSSSRLSSKTNLNIKKPSDPGAENSVAPSFLVGPSPKTVREGDTVTLDCVANGVPKPQIKWLRNGMDLDFNDLDSRFSIVGTGSLQISSAEDIDSGNYQCRASNTVDSLDAQATVQVQEPPKFIKAPKDTTAHEKDEPELKCDIWGKPKPVIRWLKNGDLITPNDYMQLVDGHNLKILGLLNSDAGMFQCVGTNAAGSVHAAARLRVVPQGVKIKKRKSQGHSTKSLQTFDNLTKRRKPFNSGEQLRTKSGGSFPFPDEDDDLDDNDSGTTRLRIPSGKLPKFEQPLNDRRFNILNAGSALPLDNQSKSYEDDDDDYDEDDPAKEALLEAYKQGEDAHKILDSWQQSKSKKSQQQKQSPASPDSPEQDPSVPHPGGKPLDSGLQARLPSQPRDLVAQIVKSRFVTLSWVEPLQNAG-DVVYYTVYYKMNNSEREQKMVTKSHDDQQVNIQSLLPGRTYQFRVEANTNFGSGASSAPLEVSTQPEVNIAGPPRNFEGYARSHKEIYVKWEEPTVTNGEILKYRVYYSENDSGADLYHDSTALEAVLTELRPHTDYVISVVPFNRNGMGDSSAEIRVKTFSSTPSEPPNNVTLEVTSSSSITVHWEPPAEEDRNGQITGYKIRYRKFKDAPQVKS--TPANIRYFELSNLDRNAEYQVKIAAMTVNGSGPFTEWNRANTLENDLDETQVPGKPIWISIHPGANNIALHWGPPQHPEIKIRNYVLGWGRGIPDENTIELKETERYHILKNLESNMDYVVSLRARNVKGDGPPIYDNIKTRDEEP------------------VDAPTPLEVPVGLRAITMSSSSIVVYWIDTMLNKNQHVTDNRHYTVSYG--ITGSNRYRYHNTTDLNCMINDLRPNTQYEFAVKVVKGRRESSWSMSVLNSTYQNVPVTPPREVTVRLDEMNPPTVIVQWIPPKHTLGQITGYNIYYTTDTTKRDRDWSVEAFAGEETMLMLPNLKPYTTYYFKVQARTTKGANNAPFSALVSYTTSAAVTMQ-EPDTIAKGIDNEK-----------------------------------LLYIIIAATAVVLLVVLLGVLLLCRRKPQSSPEHTKKSYQ--------KNNVGVPKPPDLWIHHDQMELKNIDKG--LHTVTPVCSDGASSSGALTLPRSVVHSEYEVETPVPGHVTN-SLDKRSYVPGYMTTSMNGTMERPQYP---------------------------------------RTQYSHQNRSHMTMEAGLSQQSLTQPQSNSMAQTPEHPYGGYDANFCNAGNAAAGNGCVSTIESSKR-GHPLKSFSVPGPPPTGGATPVTKHTPAVTIRPQNQSPYKKPSFSAATPNRLQ-----------GGGSVVHSTDEIQRLAPSTSTEELNQEMANLEGLMKDLSAITANEFEC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: .: * ** *:: .* .*:*:*: .. .*.*: ** * : .* * * :*** **.* . *: * ***: * :.:*:*:**.* : :. . : .: : : *:. : * :. : ::* :: .: **. :. **.* * *.:. * * *:* : .....: *.:.:*:: . ** *. *: . * **..* * * : *: : :: : . *: ::. *.*.* . : *:* * * *.* :::*** : :: * *:* * : *:* : ::*:: *.* *.::*:**** : *.**::::. :**::***::** *::**:. * .*..::.*:* :: : * * ** ***:**.:*.:**:.*:* * :. * : *:*:*. :. **: *. .: **.**.*:* * *:* *:.: *.* **.**.*.*****::.**. *:.. . * . : :.*: * **** :*::** *:. . : * .: . .:. *: .*:* : :*.:*::* * *: :: *:* *..** .*:*:::** .*.*: ::*:**. :**:********** . .:* . .... :..*:*.:** .:::*:*:**:** *:* *:*:*.****::** * : ::. ...*.: * **:: :* :*.* :.:* * *. :**::. .:**: ::**:.. .**::*:* * *:* *:*:. ** . * * *: ***::* :. .:* : * *. * *:*::** *:*** : *....::: *:* * :..*:*** ***:* *.**** *:***:. .:*:: :* :**::*** .* .* *:**:* **..: *:**** ***:**.. . :** :*...*:. : :*. *.****:***.:** . *:* *.: *. * : : .: * * : :: :**.: ... ::*:: .:* *:. : ::.: : : *.* *********:::*** ***. :.: . . .*.. .: *: : ... ** :: *:.. : * .. * :* .. : .: * *.. : .: :. . ..: : : : * ******:**. * . . *:..: .* *..:*: . * .. .* . : .. ..:**.:***:********.***: ", "identical_positions": 399, "similar_positions": 467, "identity": "23.76%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021115-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P25800-1", "uniprot_id": "RBTN1_HUMAN", "id": "P25800-1", "name": "Rhombotin-1", "aln": "MMVLDKEDGVP----MLSVQPK----------------GKQKG------------------------------------------------CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q924W9-1", "uniprot_id": "RBTN1_MOUSE", "id": "Q924W9-1", "name": "Rhombotin-1", "aln": "MMVLDKEDGVP----MLSVQPK----------------GKQKG------------------------------------------------CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQVDYEEGHLNGTFESQVQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8JFQ2-1", "uniprot_id": "RBTN1_DANRE", "id": "Q8JFQ2-1", "name": "Rhombotin-1", "aln": "-MVLDKEEGVP----MLSVQPK----------------GKQKG------------------------------------------------CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQMDYEEGQLNGSFETQVQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q99MB5-1", "uniprot_id": "LMO3_RAT", "id": "Q99MB5-1", "name": "LIM domain only protein 3", "aln": "---------------MLSVQPK----------------GKQKG------------------------------------------------CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M9PI02-1", "uniprot_id": "M9PI02_DROME", "id": "M9PI02-1", "name": "", "aln": "MMTMDITKTEPGLVGLSSNQQQQQQQQSQQSNAGMNSGGQNNGPNPNGNGNVVNVVNSGGAGGGNNGNGNVQSIAAAANNNNNNNNNGSQLCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGNLMLCKRDYLRLFGNTGYCAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCENKILCEYDYEERLVFASMANHPMLKRHVSSLGQGSPTGAAGAQNTAGGLLGGGPGGGNVNGVGMVNGPRTPGDHNNNNNGPQTPTGGGSPFAAAAAAAAAAAHMKNQLGASSXNKALGMGAAGAVVPGSGVGAGVGVGVGAASQQFYSGFGLQHQHQHQQHHQQQQQQQQLMGLGLGMGGGGGVGGGGAGSAGGPGGGAGGGGGVGSIGSGCKRYQRKFYNRN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * : *:::* ****.::*:*****:*** ********.****************.**:**:********.** ******:*********** *****:***** **:******:*:* :* ***: **** : : ", "identical_positions": 100, "similar_positions": 24, "identity": "23.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021115-9", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99612-1", "uniprot_id": "KLF6_HUMAN", "id": "Q99612-1", "name": "Krueppel-like factor 6", "aln": "MDVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQEDLWTKIILAREKKEESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEELSPTAKFTSDPIGEVLVSSGK-LSSSVTSTPPSSPELSREP--SQLWGCVPGELPSPGKVRSGTSGKPGDKGN--GDASPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O08584-1", "uniprot_id": "KLF6_MOUSE", "id": "O08584-1", "name": "Krueppel-like factor 6", "aln": "MDVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQEDLWTKFILAREKKEESELKISSSPPEDSLISSSFNYNLETNSLNSDVSSESSDSSEELSPTTKFTSDPIGEVLVNSGN-LSSSVISTPPSSPEVNRES--SQLWGCGPGDLPSPGKVRSGTSGKSGDKGN--GDASPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1R7F0-1", "uniprot_id": "F1R7F0_DANRE", "id": "F1R7F0-1", "name": "", "aln": "MDVLPMCSIFQELQIVHDTGYFSALPSLEEYWQQTCLELERYLQSEP-YVSASDLKFEGQEDLWSKLILACGDKGDGNGSLPSVKEDD----NQDCQILETNSMNSDASSEASDSSEELSPTHIFTSNPLGSVLTESAHHLSSSIISTPPSSPEMPQEPGVPQVWGSTQTDLHIPVKIRQNGLGKALDKTTTGGDASPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****************:***************************** *****::**:.*****:*:*** .* :.: .:.* :* . *****:***.***:********** ***:*:*.**..*.: ****: ********: :*. .*:**. :* * *:*.. **. ** . ***********************************************************************************************", "identical_positions": 213, "similar_positions": 39, "identity": "73.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021118-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JYH9-1", "uniprot_id": "A0A0G2JYH9_RAT", "id": "A0A0G2JYH9-1", "name": "", "aln": "MAASVQAAAAPSGVLGTCGLEQILEALKLLLSPGGSGSTSLQNTKHDVLLETLKSNLSALEAKFLKDAQWKKLKTLRDEIADKAEWPQSSEDITWSFTSQTLLLLLCLKEIMTRLVAEFNPGKPNPRTPEAAPALSPDTLSVSQQKTFQSVLQFVVTLGVCPYLMPGVGVPLRDRTEFGAVVQGIVRLEAAPHATRRLYICCRVLLDLAQHASLGSLIFCRHFGDIAAGLCQLGFCPTKRKPPVPVEEVLTEEERTLSRQALRDILDQVYQPLAVRELLILQGGSPQSCTDVKTKLRCPAPAWLRRLCGQLLSERLMRPNGVQAVVRGILEGAGAGAAGGSDAEATAADWKKCDLIAKILASCPQQSLSPESYYKDICPQILDLFHLQDKLTARQFQRVATTTFTTMLRERPELAPKYLLQPMLAPLHRCSTTAEIPESDMVPGTVLVTEEELSRCVEDVFKVYVVANEPLPVLLDSLLPLLGVFFSLYCFTQQSASHIRSLCQEILLWALVKLERKRAIASLRGFSGLDKAVPALHPQCQFRAATHGGIVITVKEALSDDEDEALYQKVSSEQSQMEHLGDLLLHCQPCGLAGDFFIFCLKELSHLLEENEAEFTPKPPCSTSLLELEQHQTLLIEDQERKLLVLQLLAVLCEKMSEQIFTHITQVVDFVAATLQRACAGLAHEAESTVGSQTLSMAMGLVAAMLGGAVQKPFVGAALKSSDFVVLKQLLPLLEKVSNTYPDPVIQELAVDLRITISTHGAFSTEAVSTAAQSTLNKKDPEQKIKEQRQTSYDASTEGTQNRPEQEQNPLRTGQGSSEPCTATSQPPGNITTEQFREVLLSACDPQVPTRAAALRTLSRWVEQREGRALEEQKKLLQIFLENLEHEDSFVYLSAIQGVALLSDVYPEEILVDLLARYDSSKDKHTPETRMKVGEVLMRIVRALGDMVSKYREPLIHTFLRGVKDPDGAHRASSLSNLGELCQRLDFLLGPVVHEVTICLTAVAKTDTDVQVRRAAVHVVVLLLRGLSQKATEMPVQLTTALRVVGTSLFALVVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQSLFAFLEHRRMRRAGRPLKLHCSQRRRSVALCIAAYQEDPEYLRKCLRSAQRIAFPNLKVVMVVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGE----TEASLQEGMERVRAVVWASTFSCIMQKWGGKREVMYTAFKALGNSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGGVGGDVQILNKYDSWISFLSSVRYWMAFNVERACQSYFGCVQCISGPLGMYRNSLLQQFLEDWYHQKFLGSKCSFGDDRHLTNRVLSLGYRTKYTARSKCLTETPTKYLRWLNQQTRWSKSYFREWLYNSLWFHKHHLWMTYESVVTGFFPFFLIATVIQLFYRGRIWNILLFLLTVQLVGIIKATYACFLRGNAEMIFMSLYSLLYMSSLLPAKIFAIATINKSGWGTSGRKTIVVNFIGLIPVSIWVAVLLGGLAYTAYC--QDLFSETELAFLVSGAILYGCYWVALLMLYLAIIARRCGKKPEQYSLAFAEV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08650-1", "uniprot_id": "HYAS3_MOUSE", "id": "O08650-1", "name": "Hyaluronan synthase 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPVQLTTALRVVGTSLFALVVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQSLFAFLEHRRMRRAGRPLKLHCSQRPRSVALCIAAYQEDPEYLRKCLRSAQRIAFPNLKVVMVVDGNRQEDTYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGE----TEASLQEGMERVRAVVWASTFSCIMQKWGGKREVMYTAFKALGNSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGGVGGDVQILNKYDSWISFLSSVRYWMAFNVERACQSYFGCVQCISGPLGMYRNSLLQQFLEDWYHQKFLGSKCSFGDDRHLTNRVLSLGYRTKYTARSKCLTETPTRYLRWLNQQTRWSKSYFREWLYNSLWFHKHHLWMTYESVVTGFFPFFLIATVIQLFYRGRIWNILLFLLTVQLVGIIKATYACFLRGNAEMIFMSLYSLLYMSSLLPAKIFAIATINKSGWGTSGRKTIVVNFIGLIPVSIWVAVLLGGLAYTAYC--QDLFSETELAFLVSGAILYGCYWVALLMLYLAIIARRCGKKPEQYSLAFAEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00219-1", "uniprot_id": "HYAS3_HUMAN", "id": "O00219-1", "name": "Hyaluronan synthase 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQSLFAFLEHRRMRRAGQALKLPSP-RRGSVALCIAAYQEDPDYLRKCLRSAQRISFPDLKVVMVVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGE----TEASLQEGMDRVRDVVRASTFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGGVGGDVQILNKYDSWISFLSSVRYWMAFNVERACQSYFGCVQCISGPLGMYRNSLLQQFLEDWYHQKFLGSKCSFGDDRHLTNRVLSLGYRTKYTARSKCLTETPTKYLRWLNQQTRWSKSYFREWLYNSLWFHKHHLWMTYESVVTGFFPFFLIATVIQLFYRGRIWNILLFLLTVQLVGIIKATYACFLRGNAEMIFMSLYSLLYMSSLLPAKIFAIATINKSGWGTSGRKTIVVNFIGLIPVSIWVAVLLGGLAYTAYC--QDLFSETELAFLVSGAILYGCYWVALLMLYLAIIARRCGKKPEQYSLAFAEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AJI3-1", "uniprot_id": "A0A8M3AJI3_DANRE", "id": "A0A8M3AJI3-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTTMPSRFGTAVRIFITTLFAAVVLFAILLAYVTGYQFIHTEQHHLSFGLYGAFLSLHLLLQSLFAYLEHRQMRGPSRPQ-----HLRRTVALCIAAYQEDPDYLRKCLRSIRRISFPGLKVVLVVDGNRQEDAYMMDIFQEVMGGVEQTGCVVWKGNYHSNGDGGGGGGKGSVHAEEAARVARVVRSCRYSCIMQEWGGKREVMYTAFKALGDTVDYMQVCDSDTVLDPACTIEMLKILEEDPDVGGVGGDVQILNKYDSWISFLSSVRYWMAFNVERACQSYFGCVQCISGPLGMYRNSLLQQFLEPWYHQTFLGSKCSFGDDRHLTNRVLSFGFKTKFTARSQCQTETPTQYLRWLNQQTRWSKSYFREWLYNALWFHKHSLWMTYESVVTGFFPFFLVATVIHLFYRGRLWNILLFLLTVQLVGMVKATYACFLRGSLVMIFMSLYSLLYMSSLLPAKIFALLTINKAGWGTSGRKKMVVNLIGAVPVTVWTAILLGGVVYTIYCEVQEPFTETEKALLIAGTIVYASYWLILLVLYLAIVAKRCNKREEQFHLSYAEA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** :: **:*:. *:*** .** .** ************:*:********:*.****:*****:****:** ..:. :************:******** :**:**.****:*********:**:***:**:**.**:* .**:.*:*. *:* . : * ** ** :. :*****:****************::***:******************::*****:*************************************************************** ****.********************:*::**:****:* *****:**********************:****** *****************:****:******:**************::**********. **********************: ****:********.:***:** :**::*.*:****:.** ** *: *:*** *:*::*:*:*..**: **:*****:*:**.*: **: *::**.", "identical_positions": 415, "similar_positions": 94, "identity": "26.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021119-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35462-1", "uniprot_id": "DRD3_HUMAN", "id": "P35462-1", "name": "D(3) dopamine receptor", "aln": "------------------MASLS-----QLSGHLNYTCGAENS--TGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQT-----------------------------------------------LSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLG--------PLQP--RGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P30728-1", "uniprot_id": "DRD3_MOUSE", "id": "P30728-1", "name": "D(3) dopamine receptor", "aln": "------------------MAPLS-----QISSHINSTCGAENS--TGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSICSISNPDFVIYSSVVSFYVPFGVTVLVYARIYMVLRQRRRKRILTRQNSQCISIRPGFPQQSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKPYPQKCQDPLLSHLQPLSPGQTHGELKRYYSICQDTALRHPNFE-GGGGMSQVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLKLG--------PLQP--RGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QG18-1", "uniprot_id": "F1QG18_DANRE", "id": "F1QG18-1", "name": "D(3) dopamine receptor", "aln": "MGFCFGSSLEKLNRSSTLMAMFSSGEWLWNDSEHSFTPGGNYSPASGVEEAK-RNYYAMLYSLLILAIVFGNVLVCIAVLRERALQTTTNYLVVSLAVADLLVASLVMPWAVYLEVVGGAWLFSRLYCNVFVTLDVMMCTASILNLCAISIDRYTAVVMPVLYN--TTHSSRKRVSVMIATVWVLAFAVSCPLLFGFNTTDDPAVCSISNPDFVIYSSVVSFYLPFAVTLLVYVRIYIFLR-RRRKKITFRQGSGKVQPASAPPSVEMCLQDDAHKE----KRDLSPIRINVITESKEQVIRPRLLANCLRRKRPQTAPAENSLLPPVITLNYCSISQASFARTEQDANREEEEGG--DEEQVAVRSCEVKKLANGRTHTSLRPPRAAHAMVCPSQARCRSMHSKEKKATQMLAIVLGVFLICWLPFFVTHILNTHCRACHIPPEVYSAFTWLGYVNSALNPVIYTTFNIEFRRAFIKILSC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** :* ... . * *.: * :*...*: : ***: *. *****:*** *** ***:***********************:*****.*****.**.* ***: *:******************************** *: * :** :**::**::*******************.**::******************:**.**:***.***:.*: ****:* **.* . .. *. .. :. .* : :: ..* .: *. . . .. * **:**:*** ***: * *. *.: :*******:.****.*::******:**:*****::**:.**:* * ***********************:**:*****", "identical_positions": 243, "similar_positions": 84, "identity": "50.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021120-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10643-1", "uniprot_id": "CO7_HUMAN", "id": "P10643-1", "name": "Complement component C7", "aln": "----MKVISLFILVG------FIGEFQSFSSASSPVNCQWDFYAPWSECNGCTKTQTRRRSVAVYGQYGGQPCVGNAFETQSCEPTRGCPTEEGCGERFRCFSGQCISKSLVCNGDSDCDEDSADEDRCEDSERRPSCDIDKPPPNIELTGNGYNELTGQFRNRVINTKSFGGQCRKVFSGDGKDFYRLSGNVLSYTFQVKINNDFNYEFYNSTWSYVKHTSTEHTSSSRKRSFFRSSSSSSRSYTSHTNEIHKGKSYQLLVVENTVEVAQFINNNPEFLQLAEPFWKELSHLPSLYDYSAYRRLIDQYGTHYLQSGSLGGEYRVLFYVDSEKLKQNDFNSVEEKKCKSSGWHFVVKFSSHG-CKELENALKAASGTQNNVLRGEPFIRGGGAGFISGLSYLELDNPAGNKRRYSAWAESVTNLPQVIKQKLTPLYELVKEVPCASVKKLYLKWALEEYLDEFDPCHCRPCQNGGLATVEGTHCLCHCKPYTFGAACEQGVLVGNQAGGVDGGWSCWSSWSPCVQGKKTRSRECNNPPPSGGGRSCVGETTESTQCEDEELEHLRLLEPHCFPLSLVPTEFCPSPPALKDGFVQDEGTMFPVGKNVVYTCNEGYSLIGNPVARCGEDLRWLVGEMHCQKIACVLPVLMDGIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLCGSSLKWSPEMKNARCVQKEN-PLTQAVPKCQRWEKLQNSRCVCKMPYECGPSLDVCAQDERSKRILPLTVCKMHVLHCQGRNYTLTGRDSCTLPASAEKACGACPLWGKCDAESSKCVCREASECEEEGFSICVEVNG-KEQTMSECEAGALRCRGQSISVTSIRPCAAETQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3YXF5-1", "uniprot_id": "CO7_MOUSE", "id": "D3YXF5-1", "name": "Complement component C7", "aln": "----MQVTSLLILVC------FIAAFQVFSRASSPVNCKWDSYGPWSECNGCTKTQTRRRSVAVYGQYGGYPCEGSAFETQSCKPERGCPTEEGCGDRFRCFSGQCISKSLVCNGDPDCEEDGADEDKCENVAN-PSCNIDKPPPNIELTGYGYNVVTGQGKKRVINTKSFGGQCRKVFSGDGKDFYRLSGNILSYTFQVKVDNDFNYEFYNSSWSYIKHTSTEQNTFYSWKGLFSHSRNTYGHGSAKEEIDTKMKSYKLLVVQNTVEVAQFTNNNPEFLQVAEPFWKELSHLPTLYDYSAYRRLIDQYGTHYLQSGSLGGEYRVLFYVDSGSAKETGFQSDQDNACSSADFQFLFTSSADQRCMKQLETEKSTSGNKGRLLRGKPLVRGGDSGFVADLSFLDLDNPAGNKQRYSSWAGSVTRLPQVIKEKLAPLYELVKEVPCASVKRLYLKRAIEEYFDEFDPCHCRPCQNGGLAIVVETQCQCLCKPYTFGSACEQGVLVGDQAGGVDGGWNCWSSWSPCVQGKRTRSRECNNPPPRDDGKSCLGETTESKQCEDQDLEKLRLLEPHCFHSSLAPKEFCLSPPALKDGFVQGEGTMVPVGQSVVYACDEGYSLIGDPVARCGEDLQWLVGEMHCQKLACVLPGEMNGMQSHPQKPFYMVGEKVTLSCVGGMSLEGPSTLLCGSSLKWSPELKDAKCVQKATSTPPPAAPACQPWEKLQNSKCICKMPYECGSSLDVCARDESRNKILSLTICKMHVVHCHKRNYTLVGKESCTLPSPAEKVCGACPIWSKCDAQNGKCICREASECQTAGYRICVEVNG-KEETMSECEAGILRCRGQSISITAIKPCAEEAAQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PWA7-1", "uniprot_id": "A0A8M9PWA7_DANRE", "id": "A0A8M9PWA7-1", "name": "Complement component C7", "aln": "MLTCILCSIYNIKMCPQSSLIFLLTFLPYIWCEQPLNCRWGPYGDWSECDGCTKTQVRVRQVETFPQFGGKSCTGEDIQKQACLPKKSCPLQAGCENRFRCTSGQCINPSLVCNGDHNC-EDGLDEQRCTGSIV---CDKQKPPPNSDLTGRGFDELTGELRAGVINTRSFGGQCRKVFSGDHREFYRLPQNLLRYSFQVSVENDFTDDYYDSSWSYMRDE--------KQRRIIRGG----HDHKTFHNQLKQDKTYHLLIIRNEVEVAQFQNNAPEYLPLSEDFWKDLSALPITYEPSAYRLFIQRYGTHYMEEGSLGGQYRALLELDANYMMEMSRTETDFHQCITRVKRRLFYKKKTTKCVKLMKTIENFSENRNHKMPIKTDIIGGNSAYIAGLSLLDLENPDNNKQMYTKWAGSVKEFPKVIKQKLRPLHELVKEVACAGLKKVHLKRALEAYLEEQSPCHCRPCQNNGMAVLSEGVCTCVCRPGTSGNACQNGHVLGEQPGVIEGGWSCWSAWSSCSHGQKSRTRSCNNPTPRNGGKNCIGETIERRSCEEPDFEHLKILEPHCFDPTLTPVKTCKTPPPLANGFVLDPKDIYTVGKKIEYTCTDGYDRIGNPFAECTESLTWRISPMECKKSECDAPAVLRNVIVVPLKQSYRIGDSVTLSCPSGMQKDGEGEIRCRLGLSWYPDPKSVRCNPVEA-VPTQPSLLCKPWEKPGTGQCVCKMPFECKTSLHVCAT-VRPGRVNRMSVCQLGALQCLGKTFTLLQDSACSWPETKFTSCQDCHQWETCDG--SKCDCKDPEDCPDDSAHVCVSLMGGAPEMMSECEAGAWRCRGKEMNVLKIGACQS----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 335, "similar_positions": 259, "identity": "39.09%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021120-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5NCH9-1", "uniprot_id": "GRM6_MOUSE", "id": "Q5NCH9-1", "name": "Metabotropic glutamate receptor 6", "aln": "----------------MGRLR------VLLLWLAWWLSQAGIAHG---------AGSVRLAGGLTLGGLFPVHARGAAGRACGTLKKEQGVHRLEAMLYALDRINADPELLPGVRLGARLLDTCSRDTYALEQALSFVQALIRGRGDGEEASVRCPGGVPPLRAAPPERVVAVVGASASSVSIMVANVLRLFAIPQISYASTAPELSDSTRYDFFSRVVPPDSYQAQAMVDIVRALGWNYVSTLASEGNYGESGVEAFVQISREAGGVCIAQSIKIPREPKPGEFHKVIRRLMETPNARGIIIFANEDDIRRVLEATRQANLTGHFLWVGSDSWGSKISPILNLEEEAVGAITILPKRASIDGFDQYFMTRSLENNRRNIWFAEFWEENFNCKLTSSGGQSDDSTRKCTGEERIGQDSTYEQEGKVQFVIDAVYAIAHALHSMHQALCPGHTGLCPAMEPTDGRTLLHYIRAVRFNGSAGTPVMFNENGDAPGRYDIFQYQATNGSASSGGYQAVGQWAEALRLDMEALQWSGDPHEVPPSQCSLPCGPGERKKMVKGVPCCWHCEACDGYRFQVDEFTCEACPGHMRPTPNHTGCRPTPVVRLTWSSPWAALPLLLAVLGIMATTTIIATFMRHNDTPIVRASGRELSYVLLTGIFLIYAITFLMVAEPCAAVCASRRLLLGLGTTLSYSALLTKTNRIYRIFEQGKRSVTPPPFISPTSQLVITFGLTSLQVVGVIAWLGAQPPHSVIDYEEQRTVDPEQARGVLKCDMSDLSLIGCLGYSLLLMVTCTVYAIKARGVPETFNEAKPIGFTMYTTCIIWLAFVPIFFGTAQSAEKIYIQTTTLTVSLSLSASVSLGMLYVPKTYVILFHPEQNVQKRKRSLKKTSTMAAP-----PKSENSEDAK---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35349-1", "uniprot_id": "GRM6_RAT", "id": "P35349-1", "name": "Metabotropic glutamate receptor 6", "aln": "----------------MGRLP------VLLLWLAWWLSQAGIACG---------AGSVRLAGGLTLGGLFPVHARGAAGRACGALKKEQGVHRLEAMLYALDRVNADPELLPGVRLGARLLDTCSRDTYALEQALSFVQALIRGRGDGDEASVRCPGGVPPLRSAPPERVVAVVGASASSVSIMVANVLRLFAIPQISYASTAPELSDSTRYDFFSRVVPPDSYQAQAMVDIVRALGWNYVSTLASEGNYGESGVEAFVQISREAGGVCIAQSIKIPREPKPGEFHKVIRRLMETPNARGIIIFANEDDIRRVLEATRQANLTGHFLWVGSDSWGSKISPILNLEEEAVGAITILPKRASIDGFDQYFMTRSLENNRRNIWFAEFWEENFNCKLTSSGGQSDDSTRKCTGEERIGQDSAYEQEGKVQFVIDAVYAIAHALHSMHQALCPGHTGLCPAMEPTDGRTLLHYIRAVRFNGSAGTPVMFNENGDAPGRYDIFQYQATNGSASSGGYQAVGQWAEALRLDMEVLRWSGDPHEVPPSQCSLPCGPGERKKMVKGVPCCWHCEACDGYRFQVDEFTCEACPGDMRPTPNHTGCRPTPVVRLTWSSPWAALPLLLAVLGIMATTTIMATFMRHNDTPIVRASGRELSYVLLTGIFLIYAITFLMVAEPCAAICAARRLLLGLGTTLSYSALLTKTNRIYRIFEQGKRSVTPPPFISPTSQLVITFGLTSLQVVGVIAWLGAQPPHSVIDYEEQRTVDPEQARGVLKCDMSDLSLIGCLGYSLLLMVTCTVYAIKARGVPETFNEAKPIGFTMYTTCIIWLAFVPIFFGTAQSAEKIYIQTTTLTVSLSLSASVSLGMLYVPKTYVILFHPEQNVQKRKRSLKKTSTMAAP-----PQNENAEDAK---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15303-1", "uniprot_id": "GRM6_HUMAN", "id": "O15303-1", "name": "Metabotropic glutamate receptor 6", "aln": "----------------MARPRRAREPLLVALLPLAWLAQAGLARA---------AGSVRLAGGLTLGGLFPVHARGAAGRACGQLKKEQGVHRLEAMLYALDRVNADPELLPGVRLGARLLDTCSRDTYALEQALSFVQALIRGRGDGDEVGVRCPGGVPPLRPAPPERVVAVVGASASSVSIMVANVLRLFAIPQISYASTAPELSDSTRYDFFSRVVPPDSYQAQAMVDIVRALGWNYVSTLASEGNYGESGVEAFVQISREAGGVCIAQSIKIPREPKPGEFSKVIRRLMETPNARGIIIFANEDDIRRVLEAARQANLTGHFLWVGSDSWGAKTSPILSLEDVAVGAITILPKRASIDGFDQYFMTRSLENNRRNIWFAEFWEENFNCKLTSSGTQSDDSTRKCTGEERIGRDSTYEQEGKVQFVIDAVYAIAHALHSMHQALCPGHTGLCPAMEPTDGRMLLQYIRAVRFNGSAGTPVMFNENGDAPGRYDIFQYQATNGSASSGGYQAVGQWAETLRLDVEALQWSGDPHEVPSSLCSLPCGPGERKKMVKGVPCCWHCEACDGYRFQVDEFTCEACPGDMRPTPNHTGCRPTPVVRLSWSSPWAAPPLLLAVLGIVATTTVVATFVRYNNTPIVRASGRELSYVLLTGIFLIYAITFLMVAEPGAAVCAARRLFLGLGTTLSYSALLTKTNRIYRIFEQGKRSVTPPPFISPTSQLVITFSLTSLQVVGMIAWLGARPPHSVIDYEEQRTVDPEQARGVLKCDMSDLSLIGCLGYSLLLMVTCTVYAIKARGVPETFNEAKPIGFTMYTTCIIWLAFVPIFFGTAQSAEKIYIQTTTLTVSLSLSASVSLGMLYVPKTYVILFHPEQNVQKRKRSLKATSTVAAP-----PKGEDAEAHK---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NCL0-1", "uniprot_id": "A0A8M1NCL0_DANRE", "id": "A0A8M1NCL0-1", "name": "", "aln": "MPATMTSQLYAPSQSRHHRIIRAPKPHVGSLIHIMWILTMGFTPESQAASSDTQPHSIKIEGDITLGGLFPVHSRGPAGIPCGEVKKEKGIHRMEAMLYALDQINSDPDLLPNITLGARILDTCSRDTYALEQSLTFVQALIQ----KDNSDVRCSNGEPPIIPKP-ERVVGVIGASASSVSIMVANVLRLFAIPQISYASTAPELSDNNRYDFFSRVVPPDSFQAQAMVDIVKAMGWNYVSTLASEGNYGESGVDAFIQISREAGGLCIAQAIKIPREPRPGEFDKIIKRLMETSNARGVIIFANEDDIKRVLEAAKRANLTGHFLFVGSDSWGAKISPILNQEDVAEGAVTILPKRASIEGFDQYFTTRSLENNRRNIWFAEFWEDDFKCKLTRPGIRGDGGLRKCTGEERIGRDSGYEQEGKVQFVIDAVYAMAHALHSMHIDLCPGSMGVCDKMDPVDGRMLLTYIRAVNFNGSAGTGVMFNENGDAPGRYDIFQYQLSN--TTNPGYKLIGQWTNHLRLSAEDMQWSGGEKLVPDSVCSFPCESGERKRMVKGVPCCWHCELCDGYQFLLDEFNCDMCPFDMRPTPNRTACRPTPIIKLEWSSPWAIIPVFLAVLGILATTGVIATFIRFNDTPIVRASGRELSYVLLTGIFLIYLITFLMIAEPGTVVCAFRRLLLGLGMCISYSAMLTKTNRIYRIFEQGKKSVTPPKFISPTSQLIITFILISVQLLGIFIWFGVVPPHTNVDFDELRPPNPEFARGILKCDMSDLSLIGCLSYSMGLMVTCTVYAIKSRGVPETFNEAKPIGFTMYTTCIIWLAFVPIFFGTSQSTEKMFIQTTTLTVSMSLSATVSLGMLYIPKVYVIIFHPEQNVQKRKRSFKAVAQAATVSTHLSQKSSDKQNGETKVEPDRSQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * *: *:: . *::: *.:*********:**.** .** :***:*:**:********::*:**:***.: ****:*************:*:******: :: .***..* **: . * ****.*:**********************************..*************:*********:*:*******************:**:********:****:*******:**** *:*:*****.****:*********:*****:::********:*******:* ****. *: * **:*********:****** ******************::*:**** .* :.*.. **********:** ****************:******** **** *:* *:*.*** ** *****.******* ******************* :* ::. **: :***:: ***. * ::***. : ** * **:** .****:************ ****:* :***.*: ** .******:*.*****:::* ****** *::******:*** ::***:*.*:*********************** *****:*** :.:** ***:**** :****:***************:***** ********:*** * *:*::*:: *:*. ***: :*::* *. :** ***:**************.**: ***********:**********************************:**:**::*********:****:*******:**.***:*************:* .: *: :..: : : ", "identical_positions": 625, "similar_positions": 153, "identity": "68.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021125-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60264-1", "uniprot_id": "SMCA5_HUMAN", "id": "O60264-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "aln": "MSSAAEPPPPPPPESAPSKPAASIASGGSNSSNKGGPEGVAAQAVASAASAGPADAEMEEIFDDASPGKQKEIQEPDPTYEEKMQTDRANRFEYLLKQTELFAHFIQPAAQKTPTSPLKMKPGRPRIKKDEKQNLLSVGDYRHRRTEQEEDEELLTESSKATNVCTRFEDSPSYVKWGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKRWVPTLRSVCLIGDKEQRAAFVRDVLLPGEWDVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQKLVERLHMVLRPFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSAGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGRLVDQNLNKIGKDEMLQMIRHGATHVFASKESEITDEDIDGILERGAKKTAEMNEKLSKMGESSLRNFTMDTESSVYNFEGEDYREKQKIAFTEWIEPPKRERKANYAVDAYFREALRVSEPKAPKAPRPPKQPNVQDFQFFPPRLFELLEKEILFYRKTIGYKVPRNPELPNAAQAQKEEQLKIDEAESLNDEELEEKEKLLTQGFTNWNKRDFNQFIKANEKWGRDDIENIAREVEGKTPEEVIEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDTKIGRYKAPFHQLRISYGTNKGKNYTEEEDRFLICMLHKLGFDKENVYDELRQCIRNSPQFRFDWFLKSRTAMELQRRCNTLITLIERENMELEEKEKAEKKKRGPKPS-TQKRKMDGAPDGRGRKKKLKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91ZW3-1", "uniprot_id": "SMCA5_MOUSE", "id": "Q91ZW3-1", "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "aln": "MSSAVEPPPPPPPESAPSKPSAAGA-GGSSSGNKGGPEGGAAPAAPCAAGSGPADTEMEEVFDHGSPGKQKEIQEPDPTYEEKMQTDRANRFEYLLKQTELFAHFIQPAAQKTPTSPLKMKPGRPRVKKDEKQNLLSVGDYRHRRTEQEEDEELLTESSKATNVCTRFEDSPSYVKWGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKKWVPTLRSVCLIGDKEQRAAFVRDVLLPGEWDVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQKLVERLHMVLRPFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSAGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGRLVDQNLNKIGKDEMLQMIRHGATHVFASKESEITDEDIDGILERGAKKTAEMNEKLSKMGESSLRNFTMDTESSVYNFEGEDYREKQKIAFTEWIEPPKRERKANYAVDAYFREALRVSEPKAPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRSPDLPNAAQAQKEEQLKIDEAEPLNDEELEEKEKLLTQGFTNWNKRDFNQFIKANEKWGRDDIENIAREVEGKTPEEVIEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDTKIGRYKAPFHQLRISYGTNKGKNYTEEEDRFLICMLHKLGFDKENVYDELRQCIRNSPQFRFDWFLKSRTAMELQRRCNTLITLIERENMELEEKEKAEKKKRGPKPS-TQKRKMDGAPDGRGRKKKLKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B8A552-1", "uniprot_id": "B8A552_DANRE", "id": "B8A552-1", "name": "", "aln": "-MSQTESSMEQQREEEPSQLDPAGPAEDDTSEN-GHDEASDTAMDSEAQSSSPPSAKGKDLLGG---------------YEEKVQTDRTNRFEYLLKQTEVFAHFIQPAAQKTPTSPLKMKPGRPRIKKDEKQNLLSAGDNRHRRTEQEEDEELLSENSKATSVCTRFDDSPSYVKTGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLYNWMNEFKRWVPSLKAVCLIGDREERTAFIRDTLLPGEWDVCVTSYEMLIIERAVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSSEDFDAWFDTNNCLGDTKLVERLHTVLRPFLLRRIKADVEKSLLPKKEIKIYVGLSKMQREWYTKILMKDIDILNSAGKMDKMRLLNVLMQLRKCCNHPYLFDGAEPGPPYTTDLHLVVNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMWRNYGYCRLDGQTPHEERQISINAFNEPNSSKFLFMLSTRAGGLGINLATADVVIIYDSDWNPQVDLQAMDRAHRIGQKKQVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGRLVDPSMNKLGKDEMLSIIRHGATHVFASKESEITDEDIDGILERGERKTMEMKEKMANLGEGSLRNFTMDTENSVYNFEGEDYREK-KKVVTNWIEPPKRERKANYAVDAYFREALRVSEPKAPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDLPNSAEMQKEEQAKIDEAEPLNEEELEEKENLLSQGFTIWTKRDFNQFIKANEKWGRDDIENIAREVEGKTPEEVMEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDSKIGRYKAPFHQLRISYGTNKGKNYTEEEDRFLICMLHKLGFDKESVYDELRQCIRNSPQFRFDWFLKSRTAMELQRRCNTLITLIERENMELEEREKAEKKKRGPRTSSAQKRKQDGTPDGRGRKKKLKL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .*.. *. **: .: . ...* * * *. : . * .:.*..:: ::::. ****:****:***********:*************************:**********.** **************:*.****.*****:******* ****************************************************************:***.***:***:*::******:*:*:**:**.***************** *::*****************************************************:************::***:********** ******* ****************** ****:***************:**********************:**************************:***.******************************************** **********:*** ****:*****:**:*********************:**********************.* ************************************** .:**:******.:**************************** :** **:**::::**.**********.************* * ..*:*************************************************************:***********.*:***:*: ***** ******.**:*******:**:**** *.**********************************:*****************************************:********************************************.*************************************************:**********:.* :**** **:************", "identical_positions": 895, "similar_positions": 97, "identity": "85.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021204-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55028-1", "uniprot_id": "BCKD_MOUSE", "id": "O55028-1", "name": "Branched-chain alpha-ketoacid dehydrogenase kinase", "aln": "------MILTSVLGSGPRSWSSLWPLLGSSLSLRARST-----------SATDTHHVELARERSKTVTSFYNQSAIDVAAEKPSVRLTPTMMLYSGRSQDGSHLLKSGRYLQQELPVRIAHRIKGFRSLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHIQDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVITIANNDIDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRINPLFGHLDMHSGGQSGPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREESFRI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14874-1", "uniprot_id": "BCKD_HUMAN", "id": "O14874-1", "name": "Branched-chain alpha-ketoacid dehydrogenase kinase", "aln": "------MILASVLRSGPGGGLPLRPLLGPALALRARST-----------SATDTHHVEMARERSKTVTSFYNQSAIDAAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHIEDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVITIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQSGPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREESFRI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0R159-1", "uniprot_id": "B0R159_DANRE", "id": "B0R159-1", "name": "Protein-serine/threonine kinase", "aln": "MRGRVTGQAMELLGSGGCRISVTRLFLSPSAKAAAPVTGAHGVGRRFRSTSSMSSYSELARERSKTVTSFYNQSAIDASAEKPSVRLTPATMLYAGKSPDGQHILSSARYLHKELPVRIAHRIKGFRSLPFIIGCNPTILQVHELYIRAYHMLSDFPAIQDQETEARYSKMVKQLLDDHKDVVTMLAEGFRECRKHILDEMLVRNFLDTTLTSRLGIRMLATHHIALHEDNPDFVGIICRRLSPKKIIEKWVDFARRLCEHQYGNSPRVRINGHVAARFPFIPLPLDYILPELLKNAMRATMESHLDTPYNVPDVVVTIANNDTDFVIRISDRGGGIPHSILDKVMHYHFSTAEQSAQDPRMSNLFDSMTN-SGPQSGPMHGFGFGLPTSRAYAEYLGGSLAIQSMQGIGTDVYLRLRHIDGKGESFRV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:* ** :*..: * * ::: : : *:******************.:**********: ***:*:* **.*:*.*.***::**************.************:********:: *:***.*:** **:*.::*:***********:****:**.**** ** *** ***.***************:*****:******** *********************:***:*****************:********************************:****** *::**********.*. **:**.***:*** *:****:. **. : ** ************************** :**:****************: ****:", "identical_positions": 308, "similar_positions": 61, "identity": "71.79%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021205-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ANV3-1", "uniprot_id": "A0A8I6ANV3_RAT", "id": "A0A8I6ANV3-1", "name": "Neuron navigator 3", "aln": "MPVLGVASKLRQPAVGPKPVHAALPIPNLGISVSQRCSSRPLEFATPERSILSCQLTLKSTCEFGEK-------KALQGTAKDIEDS---KIYTDWANHYLAKSGHKRLIKDLQQDIADGVLLADIIQIIANEKVEDINGCPRSQSQMIENVDVCLSFLAARGVN-VQGLSAEEIRNGNLKAILGLFFSLSRYKQQQHHQQQYYQSLVELQQRVTHAAPQSEASQAKTQQDMQSSLTARYAAQSKHSGIATSQKKPTRLPGPSRVPAASS-SNKAQGASNLNRRSQSFNSIDKSKPPNYANGNEKDSSKGPQPSSGINGNTQPPSTSGQPPASAIPSPNASKPWRSKSMNVKHSATSTMLTVKQPSPATSPTP--SSDRLKPPVTEGVKSAPSGQKSMLEKFKLVNARTALRPPQATSSGPNDSGKDDDAFSESGEMEGFNSGLNSGGSTNSSPKVSPKLTPP-KAGSKNFSNKKSLLQPKEKEEKNRDKNKACAEKPGKEEKDQ-MMDATPKKTSKIASLIPKGSKTAAA--KKDSLIPSSSSGIPKPGSKVPTPKQTIS---PGSAASKESEKFRTSKGSSSQAFQKAITMEKTSTPSLSAPLEGREASQASPSSSCVLQVAHSSGQSP-----GNGAVHLPQQQQHSHPNTATVAPFIYRAHSENEGTLLPPADSCTSPTKMDSSYSKTAKQCLEELSGEDPEARRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDTTVTTEVNGRAIPNLTSRPTPMTWRLGQ-ACPRLQAGDAPSMGAGYSRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDVSSEVDVGGYMSDGDILGKSLRADDINSGYMTDGGLN-----LYTRSLN-------RVPDTATSRDVIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSISSYSNITVPSRKNTQLKTDTEKRSTTDET-WDSPEELKKTEEDLDSHVDGGAKWKGVASGLAEDSEKTGQKASLSVAQTGSWRRGMSAQGGTP--ARQKTSTSALKTPGKTDDAKASEKGKTPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTASSSFGYKKPSGVGASTMITSSGATITSGSATLGKIPKSAAIGGKS--NAGRKTSLDGSQNQED-VMHVS--SKATLQYRSLPRPSKSGTSG--IPGRGGHRSSTSSIDSNVSSKSAG--------ATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSDSVSLSGSPKSSPTSASACGTQGLRQPGSKYPDIASPTFRRLFGAKAG---GKSASAPNTEGVKSSSVVPSPSTSLARQGSLESPSSGTGSMGSAGGLSGSSS--PLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANLSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGSQSPLVSPSAMSSSATGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDDAQ-LCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKLRRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELIELRETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGNDADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHNAGESGSSSMKPSQSASA----------------------ICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLDQIREAMNRMQNEIEILKAENDRLKAETGNT-----AKPARPPSESSSTASSSSSRQSLGLSLNNLNITESVTSDILLDDTGDATGHKDGRPVKIIVSISKGYGRAKDQKSQAYLIGSIGVSGKTKWDVLDGVIRRLFKEYVFRIDTSSSLGLSSDCIASYCVGDLIRSHNLEVPELLPCGYLVGDNNIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHHRIILSGPSGTGKTYLANKLAEYVITKSGRKKTEDAIATFNVDHKSSKELQQYLANLAEQCSADNNGVELPVVIILDNLHHVGSLSDIFNGFLNCKYN-KCPYIIGTMNQGVSSSPNLELHHNFRWVLCANHMEPVKGFLGRYLRRKLIEMEIERNIRNNDLVKIIDWIPKTWHHLNSVLETHSSSDVTIGPRLFLPCPMDVEGSRVWFMDLWNYSLVPYVLEAVREGLQMYGKRA-PWEDPSKWVLDTYPWSSASLPQEGPALLQLRPEDVGYEGCTSTKEATTSKHIPQTDTEGDPLMNMLMKLQEAANYPGTQSCDSDSVSHHEDILDTSIESTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TN7-1", "uniprot_id": "NAV3_MOUSE", "id": "Q80TN7-1", "name": "Neuron navigator 3", "aln": "MPVLGVASKLRQPAVGPKPVHAALPIPNLGISVSRRCSSRPLEFATPERSMLSCQLTLKSTCEFGEK-------KALQGTAKEIEDS---KIYTDWANHYLAKSGHKRLIKDLQQDIADGVLLADIIQIIANEKVEDINGCPRSQSQMIENVDVCLSFLAARGVN-VQGLSAEEIRNGNLKAILGLFFSLSRYKQQQHHQQQYYQSLVELQQRVTHTAPQSEASQAKTQQDMQSSLTARYAAQSKHSGIATSQKKPTRLPGPSRVPAASS-SNKAQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSPKGPQPSSGINGNTQPPSTSGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQPSPATSPTP--SSDRLKPPVTEGVKSAPSGQKSMLEKFKLVNARTALRPPQAPSSGPNDGGREDDAFSESGEMEGFNSGLNSGGSTNSSPKVSPKLTPP-KAGSKNFSNKKSLLQPKEKEEKTRDKNKACAEKSGKEEKDQVTTEAAPKKTSKIASLIPKGSKTAAA--KKESLIPSSS-GIPKPGSKVPTPKQTIS---PGSAASKESEKFRTSKGSSSQAFPKAITAEKASTPSLSTPLDGREAGQASPSSSCVMQVTHSSGQSP-----GNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTSLPPADSCTSPTKMDSSYSKTAKQCLEEISGEDPEARRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDTTVTTEVNGRAIPNLTSRPSPMTWRLGQ-ACPRLQAGDAPSMGAGYSRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDVSSEVDVGGYMSDGDILGKSLRADDINSGYMTDGGLN-----LYTRSLN-------RVPDTATSRDVIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSISSYSNITVPSRKNTQLKTDAEKRSTTDET-WDSPEELKKAEGDCDSHGDGAAKWKGATSGLAEDSEKTGQKASLSVSQTGSWRRGMSAQGGTPATARQKTSTSALKTPGKTDDAKASEKGKTPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTASSSFGYKKPSGVGASTMITSSGATITSGSATLGKIPKSAAIGGKS--NAGRKTSLDGSQNQDDVVLHVS--SKTTLQYRSLPRPSKSSTSG--IPGRGGHRSSTSSIDSNVSSKSAG--------ATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGTQGLRQPGSKYPDIASPTFRRLFGAKAG---GKSASAPNTEGAKSSSVVLSPSTSLARQGSLESPSSGTGSMGSAGGLSGSSS--PLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANLSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSATGKYHFSNLVSPTNLSQFNLPAPSMMRSSSIPAQDSSFDLYDDAQ-LCGSATSLEERPRAVSHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKLRRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELIELRETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGNDADSKKKKKKNWL-------RSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHNAGESGSSSMKPSQSASA----------------------ICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLDQIREAMNRMQNEIEILKAENDRLKAETGNT-----AKPARPPSDSSSTASSSSSRQSLGLSLNNLNITESVTSDILLDDTGDATGHKDGRSVKIIVSISKGYGRAKDQKSQAYLIGSIGVSGKTKWDVLDGVIRRLFKEYVFRIDTSSSLGLSSDCIASYCIGDLIRSHNLEVPELLPCGYLVGDNNIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHHRIILSGPSGTGKTYLANKLAEYVITKSGRKKTEDAIATFNVDHKSSKELQQYLANLAEQCSADNNGVELPVVIILDNLHHVGSLSDIFNGFLNCKYN-KCPYIIGTMNQGVSSSPNLELHHNFRWVLCANHTEPVKGFLGRYLRRKLIEMEIERNIRNNDLVKIIDWIPKTWHHLNSFLETHSSSDVTIGPRLFLPCPMDVEGSRVWFMDLWNYSLVPYVLEAVREGLQMYGKRA-PWEDPSKWVLDTYPWSSASLPQEGPALLQLRPEDVGYEACTSTKEATTSKHIPQTDTEGDPLMNMLMKLQEAANYPSTQSCDGDSVSHREDILDTSIESTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IVL0-1", "uniprot_id": "NAV3_HUMAN", "id": "Q8IVL0-1", "name": "Neuron navigator 3", "aln": "MPVLGVASKLRQPAVGSKPVHTALPIPNLGTTGSQHCSSRPLELTETESSMLSCQLALKSTCEFGEK-------KPLQGKAKEKEDS---KIYTDWANHYLAKSGHKRLIKDLQQDIADGVLLAEIIQIIANEKVEDINGCPRSQSQMIENVDVCLSFLAARGVN-VQGLSAEEIRNGNLKAILGLFFSLSRYKQQQHHQQQYYQSLVELQQRVTHASPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGS-SSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTP--SSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSGGSTNSSPKVSPKLAPP-KAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQ-VTEMAPKKTSKIASLIPKGSKTTAA--KKESLIPSSS-GIPKPGSKVPTVKQTIS---PGSTASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSGSCTMTVAQSSGQST-----GNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRTIPNLTSRPTPMTWRLGQ-ACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLN-----LYTRSLN-------RIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDET-WDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAP--SRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKS--NAGRKTSLDGSQNQDDVVLHVS--SKTTLQYRSLPRPSKSSTSG--IPGRGGHRSSTSSIDSNVSSKSAG--------ATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAG---GKSASAPNTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSS--PLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDDSQ-LCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKLRRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELIELRETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGNDADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHNAGDCGSASMKPSQSASASPLVWPPKKRQNGPVIYKHRSRICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLDQIREAMNRMQNEIEILKAENDRLKAETGNT-----AKPTRPPSESSSSTSSSSSRQSLGLSLNNLNITEAVSSDILLDDAGDATGHKDGRSVKIIVSISKGYGRAKDQKSQAYLIGSIGVSGKTKWDVLDGVIRRLFKEYVFRIDTSTSLGLSSDCIASYCIGDLIRSHNLEVPELLPCGYLVGDNNIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHHRIILSGPSGTGKTYLANKLAEYVITKSGRKKTEDAIATFNVDHKSSKELQQYLANLAEQCSADNNGVELPVVIILDNLHHVGSLSDIFNGFLNCKYN-KCPYIIGTMNQGVSSSPNLELHHNFRWVLCANHTEPVKGFLGRYLRRKLIEIEIERNIRNNDLVKIIDWIPKTWHHLNSFLETHSSSDVTIGPRLFLPCPMDVEGSRVWFMDLWNYSLVPYILEAVREGLQMYGKRT-PWEDPSKWVLDTYPWSSATLPQESPALLQLRPEDVGYESCTSTKEATTSKHIPQTDTEGDPLMNMLMKLQEAANYSSTQSCDSESTSHHEDILDSSLESTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5TZ18-1", "uniprot_id": "NAV3_DANRE", "id": "Q5TZ18-1", "name": "Neuron navigator 3", "aln": "--------------------------------MAHGLAPRSSELRVTESPMLSCQLSFKTEIHDRRTNLVPAPAATLARSSREAEESKICKIYTDWANHYLAKSGCPRLIKDLTQDIPDGVLLAEIIQIIANEKIEDINSCPKSHSQMIENVECCLSFLGARGVS-VQGLSAEEVCNGNLKSILGLFFILSRYKQQQQHQQQYLQSLVELQQHVTHQTTGAAQLSQHKTQDMQSSLTARYTSPPGHSGIAAPQKKNTRLPGPSRVPAAGSGSNSSKGSSNLNRRSQSFNSIDKSKPLQYASGNDRGSMNGS--------GSVPSSTSGQQLASAIPSPTAGKTWRSKSMNMKHSATSSMLATKPPSPTSSPTPPSSSDRLRPPITDASKSAPGNQRSMLEKFRILNPRATSR---TSPSVAEMALQEEDDLSEFGDEGTFSPTPPCGISKQQGKPSASAFAPPSKSNNCKNHNNKSLPQPKDKEDKNKTKNKASTP-----PKEEPVIVETSKKGSKIASLIPKGSKTSAASVKKESAIPASS-SIPKPGLKAPTATSKPAGTQSCVPATTGGEKTKLNKGSQS------IYMQRSLGG-----LENRKTSMVLSTSTSALSASTTSGLGGGCALGGNGAVQLPQQQQHNHPNTATVAPFMYRTYSENDCTTVVPPEPCLSPTK-ELVYGKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQITHSTLETTFDTTVTTEVNGRGLPALSSRSSPMSWRLGQGSSPRLQAGDAPSYTPPRSSAGSTTVRYGEPSRLLYTAPLRRAAASGARGAEPGEKGGIS----EVGPEVDVTGYGSDGDILAKNVHADDIS-GYHTDGGIYSRNVDLYSRNVG-------RPAEMTPAREVVQKGVKEMQGE-DSWDDSSSVSSGLSDTLDNISTDDLNPAP----YSGISSRKSKAAQSNKETHRHIEQDASSWAGAEDLKKVDEEMEPGMDPSCKWKTSSPSSSCQGEDISQKTGLPMSQTGSWRRGMSAQVGITP-PRTKGTSTSLKTPGKTDDAKASEKGKGSPKSPSIQRSPSDAGKSSGDEGKKPPSGIARPPTTSSFGYKKIPGP-AGALITASGATLTSGSATLGKVPKSACIGKSTGISNGRKTSLDGAQHQDDAVLLGCGGSEVPLQYRSLPRPAKSSSGGSSVVSRSGHRSSSSSIDSNVSGKSAGGSGVAVGTPTSTKRRDTGKVGSGRSSPVTINQTDKEK--VAGSDQEGTGLPTSPKSSPTST----QSGLRQPGSKYPDIASPTFRRLFGSKAS---SKPSSPGTPDSGKCPSALGSPHGTLARQASLDSPSSGTGSLGSMGGQSGGSS--PLYGKTPDLGTDSP------ASSPASGLSLPSNARPWPPNLSSSSAGSKDTLSCHSMTSLHTSSESIDLPLPHHHGPK------------VTRTGSVKSTLSEGMPLDRNTLPKKGLR------QTSHEEGKEWLRSHSTGGLQDTGSP---LSPPGTTCANAGKYHYSNLLSPTSMSQYNIPSTSMSRSNSIPAQDS-FELYGEGHPLGGSATSLEERPRGMSRSGSFRDSTDEVHGSSLSLVSSTSSLYS--------AQIRKLRRELDASQEKVATLTSQLAANAHLVAAFEKSLANMTCRLQSLTMTAEQKESELAELRETIEALKTQNTDAQTAIQVALNGPDHVHRDLRIRRQHSSESMSSINSAASHSSLGSAKDAEDKKKKKKSWL-------RSSFKQAFSKKKTNKPQSSHDEIEEMTDSSLPSSPKLLHISRQASSPQPLLSSPSTT---------------------ELCECTEAEAEIILQLKNELREKELKLTDIRLEALSSAHHLDQIREAMNRMQNEIELLKAENDRLKSSGNTTPAATPAKTARPPSETSS-TSSSSSRQSLGLSLNNLNITDTIMSDILLDDGYEGNLRKEGRSVRIVVTINSDSNKTKAMQKKQYLIGSIGVSGKTKWDVLDGVIRRLFKEYVFRVDPLTSLGMNSDSIVCYRMGDVVRSHASEVPELLPCGYLVGDNNVITVTLKGVKEGSIDDLVFDTLIPKPIIQRYLNLLMEHRRIILSGPSGTGKSYLATKLAYFILSKTGREVTDTNLATFNVDQKSSKDLRQYLSSLAEQCNTEECEIELPTVVILDNLHHIGSLSDIFNGFLNCKYH-KCPYVIGTMNQGVSSSPNLELHHNFRWVLCANHTEPVKGFLGRFLRRKLIETEIDKNMRSNDLIKIIDWIPKIWQHLNSFLEAHSSSDVTIGPRLFLSCPMDADGSRVWFTDLWNYSLVPYLLEAVREGLQHEGQ----------------------------SLLQLRPEDVGYDGYSSSKDGAASKQVSQSDTEGDPLMNMLMRLQEAANYSSAQSCDSDSASHHEDLLDSSLESAL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIQ9-1", "uniprot_id": "NAV_DROME", "id": "Q9VIQ9-1", "name": "Protein neuron navigator", "aln": "--------------------------------------------------MLARCVSYQGSCDNING----------------ILTRDYAEIYTDWANYYLERAKSKRKVTDLSADCRDGLLLAEVIEAVTSFKVPDLVKKPKNQQQMFDNVNSCLHVLRSQSVGGLENITTNDICAGRLKAVLALFFALSRFKQQAKQTKSIGVGCGGGVGGSSSTLTGSGSVLGIGIGGLRTPGSSLNQDKNQQEQQQQQQQQQTPQQLAQSLENGNEMVNRQIAPAYAKVNGGTAIPLPATVMVQRRCPPDK---------------VRPLPPTPNHTPSIPGLGKSGSDFNTSRPNSPPTSNHTIQSLKSGNNNSLRPP---SIKSGIPSPSSPQTAP-QKHSMLDKLKLFNKEKQQNAVNAASVASKTQIQSKRTSSSSGFSSARSERSDSSLSLNDG--HGSQLKPP----SISVSSQKPQPKTKQSKLLAAQQKKEQANKATKLDKKE----KSPARSLNKEESGNESRSSTMGRTGKSSLVRAVG-GVEKNTPKTSSKSSLHS----KSDSKSSLKAPQLLQSPSSGGLPKPIAAIKGTSKLPSLGGGAGHLPAAESQQNQQLLKRETSDISS-----------------NISQPPPAEPPISTHAHIHQNQTPPPPYYANSQPTSHISSHGFLSEPSTPQHSSGIYGSSRLPPPKSALSAPRKLEYNAGPHILSSPTHHQRQGLPRPLVNSAPN-----TPTASPNKFHTIPSKIVGTIYESKEEQLLPAPPPASGGSSILPMRPLLRGYNSHVTLPTRGARGGHHP-HQSYLDFCESDIGQGYCSDGDALRVGSSPGGSRFHDIDNGYLSEGSSGLNGPSSSAGGISPGKHFLSMMRARTQLPTTIEERIRNSRGSLDSIGTAANGSSAASQASSSGGSTTTHAQNNNNNNNNNSGGGAKMDGSPHHRPGSRNGRDNWSKMPEPLNGQKVEKSDKSSPSRRSMGGGGSGSSSKQGSPSSSSRTKGVPPSFGYVKRANGSIASTAEQQNIAMMMAAGGAGANGLPCGR---TAHVSAVPRTAS--GRKVAGGTQTLPNDMNKLPPNTQHRSFSLTGPTATQLSQSIRERLATGSHSLPKPGSDLHVFQHRISNRGGTRHDGSLSDTQTYAEVKPEYSSYAMWLKHSNTAGSRLSDGESVEQLQIGSPALTRHGHKMIHNRSG------------GPGQMAGQMSGNESPYVQSPRMNRSNSIRSTKSEKMYPSMMSRAGEVEIEPYYCLPVGTNGVLTAQMAAAMAAQSQAAQGNPGVGVNVGGVAWSQPTSPTPLTRGPFNTAAGASVLSPTHGTTSAAGLVGPGGGAGGGAMVGHRLTYPKKNDEVHGSAASLLSGGSSLYGNAEERQAHEIRRLKRELQDARDQVLSLSSQLSTNAHVVTAFEQSLSNMTNRLHQLTATAERKDGELTDMRQTIELLRKQSIQAGLTTAHMQSMGVQTQGQGQVQGQALG--------------------QALGQPGSDQKPPNSGSQRAINANNGSMPLGMQRQHSTDSMCSLNS-ISSGCSAAQDKNKANKKKGWLRSSFTKAFSRNAKISKTS--------------RHVGHHHHHNHSQQELASGKLPLHNGHGEPLGLASLATQPAPPLPNSKQSSPAKTVTLIDNAKPIDAIDQEDQHVVEDLKKQLREKDLVLTDIRLEALSSASQLESLKEMMNKMRAEMMSLKHNNERLQKLVTTRSLAGSEASLGQAISPNGSVAGSSEVSRRYSLADSNSRPPMELPAR---------------------------------------LSEELELEEDCLPPAPAPEQPPPPAPNGVSVAPLSPSTHVDLTPPPP---------------ALEAAPMAS------PVHMASATEELADVCDGKKIAIACYLGQPEAFAKYCEELQELDGFYANGHEADS-----QSQSERKSNYTSASCNEFVIACTYISGKTTWQNLDYVVRKTFKDYVARIDPGTNLGLNTDSITSYHLGEAKRGPEMGFPELLPCGYIVGSVRTLYICLQGVG-----SLAFDSLIPRSIVHRYISLLTEHRRLILCGPSGTGKSYLARRLAEFLVARSARGNPSEAIATFNVDHKSSKDLRQYLGHIAEQAAIANGVSELPSVIILDNLHHASALGDVFSCLLSAGPANKLPCIIGTMSQATCNTTNLQLHHNFRWVLTANHMEPVKGFLGRFLRRRLFQLELQTQHPQPELAAVLAWLPSVWQHINRFLEVHSSSDVTIGPRLFLACPMDLKDSQVWFTDIWNYHLSPYLVEAVREGVQLYGRRGGAWNDPSAFIRNSYPWPYG--PDSVPPLRQINAEDVGLEGVALTN-----------GDQQDPLLNMLMRLQEAANYSEAQDQESDCASLDSNVTPESSAGAE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: :: : . . :*******:** :: * :.** * **:***::*: ::. *: *: *:.:.**::**: ** .* ::.*. ::.:::::: *.**::*.*** ***:*** :: :. . : . : .:::. :: :. *:: * .. : ... . ..: : .. : .: . : :: * ..: : .* .:.. :.:. * ::. :: : * . : .* * : * ... ::** ::***:*:::.* . . ... .. :.. *. * . .. * :.. .. : ** . . .:*. :.*:.: ::* : *.: :. : : . :. .:: . *.* : : . .: * *..: .. : :.. : : :.. * * : . . . . : :*. . : ..: .*: ::: .:: * . . .**. :. :: . : *. : *: . *. . ::** . .. :. :* : . *.: * :: .. : .: . :: : . . :* : . * *.: : .: . . . . ::. * . . : .**. ** ::*. : .:. : ::. ::: . ** . ::. **. *:: .. .: :. .. : * . . .* *: . : . . . : . . . : ..:. . . . *: *: . . .. : : : : * :. .. : . : .:: *:.* *:. .. :. *..: : ...:.. . .* : : : :::** :* * .. : . * . .. .. : . *. .: : ... :.* : .: : . :: : :* : **..** . . :.. : :..: . .::. .. : * .::*:. : .::.. . . . ...: : . * .*: **: ** * .. * .*.:. .: .: .. ** :. *: ... .: . : : :: * . .: ... . . *... : : : : * *: : ** : :*: ::.:: * : *: .*.. ** : . . . .: *.* .: . : ...:: ::: :. .:.* :*.* :... . .: .:: : ::. **:::*: . * . .: . : : * . . :: * * : :.*: :. :: . :: *. * *:*:. *:..:.*::. .: . ..::: :* .:*: **:. : : *. . .::**. .. :* :.* * * : : : ..: : .**.: *:* . *:: : ..: . ....: ::. *.: : .:: * .. :: . : .. .. . . : ::*.. :****.*: ** *:*: **:** *:*. :.**:.:*.*..* :*: *. .********:**. . : : *:** .:.**:***:.* :**:.** **:*:**.*******:*** :** ::::::.* .. :******:****:*:***. :***. : *** *:******* .:*.*:*. :*.. * * :****.*....:.**:********* *** *********:***:*:: *:: : . :* :: *:*. *:*:* .**.**************.**** ..*:*** *:*** * **::******:* *: .* *:..**** :. : :: . : ***:****:*******. :*. :.:..* .:: * .: ", "identical_positions": 387, "similar_positions": 779, "identity": "15.76%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021206-10", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K3U6-1", "uniprot_id": "FA7_RAT", "id": "Q8K3U6-1", "name": "Coagulation factor VII", "aln": "MVPQTHGLLLLYFLLQLQGPLGA---------------------VVFITQEEAHGVLHRQRRANS-LLEELWSSSLERECNEERCSFEEAREIFKSPERTKQFWTIYSDGDQCASNPCQNGGTCQDHLKSYVCFCPLDFEGRNCEKNKNEQLICANENGDCDQYCRDHVGTKRTCSCHEDYVLQPDEVSCKPKVEYPCGRIPVVEKRNFSRPQGRIVGGYVCPKGECPWQAVLKFNEALLCGAVLLDTRWIVTAAHCFDKFGKLVNITVVLGEHDFSEKEGTEQVRLVEQVIMPNKYTRGRTDHDIALVRLHRPVTFTDYVVPLCLPERAFSENTLASIRFSRVSGWG-----QLLDRGATALELMVIEVPRLMTQDCLEHAKHSANTPRITENMFCAGYMDGTKDACKGDSGGPHATHYHGTWYLTGVVSWGEGCAAIGHIGVYTRVSQYIDWLVKYMDSKLRVGISRVSLL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70375-1", "uniprot_id": "FA7_MOUSE", "id": "P70375-1", "name": "Coagulation factor VII", "aln": "MVPQAHGLLLLCFLLQLQGPLGT---------------------AVFITQEEAHGVLHRQRRANS-LLEELWPGSLERECNEEQCSFEEAREIFKSPERTKQFWIVYSDGDQCASNPCQNGGTCQDHLKSYVCFCLLDFEGRNCEKSKNEQLICANENGDCDQYCRDHVGTKRTCSCHEDYTLQPDEVSCKPKVEYPCGRIPVVEKRNSSSRQGRIVGGNVCPKGECPWQAVLKINGLLLCGAVLLDARWIVTAAHCFDNIRYWGNITVVMGEHDFSEKDGDEQVRRVTQVIMPDKYIRGKINHDIALLRLHRPVTFTDYVVPLCLPEKSFSENTLARIRFSRVSGWG-----QLLDRGATALELMSIEVPRLMTQDCLEHAKHSSNTPKITENMFCAGYMDGTKDACKGDSGGPHATHYHGTWYLTGVVSWGEGCAAIGHIGVYTRVSQYIDWLVRHMDSKLQVGVFRLPLL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08709-1", "uniprot_id": "FA7_HUMAN", "id": "P08709-1", "name": "Coagulation factor VII", "aln": "MVSQA--LRLLCLLLGLQGCLAAGGVAKASGGETRDMPWKPGPHRVFVTQEEAHGVLHRRRRANA-FLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWG-----QLLDRGATALELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UZT1-1", "uniprot_id": "A0A8N7UZT1_DANRE", "id": "A0A8N7UZT1-1", "name": "", "aln": "MRVGAAAVLLCVLTLRSTS-------------------------AVFLSKDEASALLQRFRRANSGFLEEMKAGNLERECVEEICDYEEAREVFEDDDRTKQFWLSYSNKEPCLTNPCRNNGTCVYLADSYYCLCSEGYEGKYCEKGLEETLKCQYVNGGCEQFC-DGSGARRSCSCAEGYALADDGTSCVSQVDYPCGKIPVQKN----TSQNQFLGGIHCPRGHCPWQVLIDYNGESVCGGALLEGPWLITAAHCVHQKDTR-FLKAVTGEHDLDVLDGSEEPYEVSAVFIHPNYDPETLDSDLALLRLRVPVQRSLYAVPICLPTPQLARSELWAARFHTLSGWGTRTAGHNLRREKGLKGPASGTLQRLAVP--LLPAAQCGN-ANTTANMFCAGYTEGDHASCRGHDGSPLVTRYGETSFLTGVVSWGRGCGPPGYYWIYTKVENFLIWMDTVMKTNTEDKSEQIANVSTKN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : * : * . **::::** .:*:* ****: :***: ...***** ** *.:*****:*:. :*** ** **: : * :.**:*.*:* .** *:* :**: **. :: * * **.*:*:* * *::*:* * *.* * * .** . *:****:**: :: *.:::** **:*.****.:: * :**..*:: *:::****..: : .* ****:. :* *: * *:: .* : *:**:**: ** : :.**:*** ::. * ** :**** : * * : ** . * : : .: .. * ****** :* : :*:*..*.* .*:* * :***:****.**.. *: :**:*.::: *: * :: . . . ", "identical_positions": 159, "similar_positions": 128, "identity": "33.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021206-13", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FJQ3-1", "uniprot_id": "F7FJQ3_RAT", "id": "F7FJQ3-1", "name": "NPC intracellular cholesterol transporter 2", "aln": "MTLNDSSYPNLTTPSSELPSLHLPHCTAFMPRMSFLTPTILLLALVAATQAEPLHFKDCGSKVG--VIKEVNVSPCPT----QPCQLHKGQSYSVNVTFTSGTQSQN-STALVHGILAGVPVYFPIPEPDGCK-----CGINCPIQKDKVYSYLNKLPVKSEYPSLKLVVEWKLQDDKKDN--LFCWEIPVEIKG-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0J0-1", "uniprot_id": "NPC2_MOUSE", "id": "Q9Z0J0-1", "name": "NPC intracellular cholesterol transporter 2", "aln": "--------------------------------MRFLAATILLLALVAASQAEPLHFKDCGSKVG--VIKEVNVSPCPT----DPCQLHKGQSYSVNITFTSGTQSQN-STALVHGILEGIRVPFPIPEPDGCK-----SGINCPIQKDKVYSYLNKLPVKNEYPSIKLVVEWKLEDDKKNN--LFCWEIPVQITS-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61916-1", "uniprot_id": "NPC2_HUMAN", "id": "P61916-1", "name": "NPC intracellular cholesterol transporter 2", "aln": "--------------------------------MRFLAATFLLLALSTAAQAEPVQFKDCGSVDG--VIKEVNVSPCPT----QPCQLSKGQSYSVNVTFTSNIQSKS-SKAVVHGILMGVPVPFPIPEPDGCK-----SGINCPIQKDKTYSYLNKLPVKSEYPSIKLVVEWQLQDDKNQS--LFCWEIPVQIVSHL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DGJ3-1", "uniprot_id": "NPC2_DANRE", "id": "Q9DGJ3-1", "name": "NPC intracellular cholesterol transporter 2", "aln": "--------------------------------MDYRVLGVVLLSFLAYTCADPVKFVDCGSVDG--KVVQVDIKPCSQ----QPCKLHKGQSYTVNVTFSSGVESQT-SKAVVHGVLAGVPVPFPIPIDDGCK-----SGIQCPIVPQKPYNYVTELPVKTEYPAIKVVVEWELRDDSSKD--LFCIKFPVQIVN-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQ62-1", "uniprot_id": "NPC2_DROME", "id": "Q9VQ62-1", "name": "NPC intracellular cholesterol transporter 2 homolog a", "aln": "-----------------------------------MLRYAVIACAALVVFAGALEFSDCGSKTG--KFTRVAIEGCDTTK--AECILKRNTTVSFSIDFALAEEATA-VKTVVHGKVLGIEMPFPLANPDACVD----SGLKCPLEKDESYRYTATLPVLRSYPKVSVLVKWELQDQDGAD--IICVEIPAKIQ------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VA42-1", "uniprot_id": "Q9VA42_DROME", "id": "Q9VA42-1", "name": "", "aln": "----------------------------MLRPSSLQAVAIAIVLISSSASAEVVNFEPCPDSVDTCTIQQVRVSPCPEALNNAACNIRRKHNSEMSFDFTPNFDADTLVASLGWAKSENVELPLLTLDSAACK------YTPCPVRSGVKQTYTTLVPIEAKFPLSPYTIRWALKDPVSQK--RCCFTIDIKVVR-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VA41-1", "uniprot_id": "Q9VA41_DROME", "id": "Q9VA41-1", "name": "", "aln": "----------------------------MLRLSSLLPVAFALVLS--SVSAEIVNFQTCEDSVDSCSISQVRVTPCPEANANAACHIRRRHRFTMSFDFTPHFDADTLVASLGWAKSENVELPLLTMDQEACK------YTTCPVRSGVTQTYTNNMPADARFPLSPYTIRWALKDPVSQK--RCCFTIDIKVVR-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VH31-1", "uniprot_id": "Q9VH31_DROME", "id": "Q9VH31-1", "name": "", "aln": "------------------------------MSSFKKLSLCLVLSIMWTSVADSTPIRQCADSNYP-QPLMVQIDDCDA----LPCDLWKGTEAKIDIQFVATRNTMKKLSAEVHLTSLGVTIPYDLEASRGNVCSNLLHGAYCPLDAGEDVTYQLLLPVTTNQPEVPTRLEVRLLDSDDENRVVSCFLADTRVKKPRSAV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : * . * : * * : : ... * :: : .: : . **: * :* * :. * * . * .: ", "identical_positions": 14, "similar_positions": 23, "identity": "7.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021206-14", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WV98-1", "uniprot_id": "TIM9_MOUSE", "id": "Q9WV98-1", "name": "Mitochondrial import inner membrane translocase subunit Tim9", "aln": "-------MAAQIPESDQIKQFKEFLGTYNKLTETCFLDCVKDFTTREVKPEEVTCSEHCLQKYLKMTQRISVRFQEYHIQQNE---ALAAKAGLLGQPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WV97-1", "uniprot_id": "TIM9_RAT", "id": "Q9WV97-1", "name": "Mitochondrial import inner membrane translocase subunit Tim9", "aln": "-------MAAQIPESDQIKQFKEFLGTYNKLTETCFLDCVKDFTTREVKPEEVTCSEHCLQKYLKMTQRISMRFQEYHIQQNE---ALAAKAGLLGQPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5J7-1", "uniprot_id": "TIM9_HUMAN", "id": "Q9Y5J7-1", "name": "Mitochondrial import inner membrane translocase subunit Tim9", "aln": "-------MAAQIPESDQIKQFKEFLGTYNKLTETCFLDCVKDFTTREVKPEETTCSEHCLQKYLKMTQRISMRFQEYHIQQNE---ALAAKAGLLGQPR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W762-1", "uniprot_id": "TIM9_DANRE", "id": "Q9W762-1", "name": "Mitochondrial import inner membrane translocase subunit Tim9", "aln": "-------MAAQVTESDQIKQFKEFLGTYNKLTENCFMDCVKDFTTREVKPEETTCSESCLQKYLKMTQRISMRFQEYHIQQNE---RWPQKPDY-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYD7-1", "uniprot_id": "TIM9_DROME", "id": "Q9VYD7-1", "name": "Mitochondrial import inner membrane translocase subunit Tim9", "aln": "MAKTPENIAIDQLDKDQIKTFSDFLMSYNKLSETCFTDCIRDFTTRDVKDSEEKCSLNCMEKYLKMNQRVSQRFQEFQVIAHENALAMAQKTGKL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O74700-1", "uniprot_id": "TIM9_YEAST", "id": "O74700-1", "name": "Mitochondrial import inner membrane translocase subunit TIM9", "aln": "MDALNSKEQQEFQKVVEQKQMKDFMRLYSNLVERCFTDCVNDFTTSKLTNKEQTCIMKCSEKFLKHSERVGQRFQEQNA-------ALGQGLGR-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : * :.:*: *.:* * ** **:.**** .:. .* .* * :*:** .:*:. **** : . ", "identical_positions": 24, "similar_positions": 24, "identity": "24.24%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021206-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ERS8-1", "uniprot_id": "SEBOX_RAT", "id": "Q9ERS8-1", "name": "Homeobox protein SEBOX", "aln": "--------------------------------------------------------------------------------------------------------------MASPVEASPG-CASGL------------------------GPHRRKRTTFSVGQLLELERVFAARPYPDISTREHLAQITHLPEAKIQVWFQNRRAKR------IKDRKPGALNARLELPPN-CSLPDTP-----------------------QLSWDPGTPSHP--------------LHS---------TSSAQQTSACPPQTSCLAPILG---PGQS---WSG-AKAAAPWG------TSEVSGVHS-LEQIVP-----------------------QTSLGNLSDLIYTSAIVTNVDHS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70368-1", "uniprot_id": "SEBOX_MOUSE", "id": "P70368-1", "name": "Homeobox protein SEBOX", "aln": "--------------------------------------------------------------------------------------------------------------MASPVEASPG-CASGL------------------------GPHRRKRTTFSVGQLVELERVFAARPYPDISTREHLAQVTHLPEAKIQVWFQNRRAKR------IKDRKPGALNSRLELPPNSCSLPDTP-----------------------QLPWDPGTSSHP--------------LHP---------TSSAQYTSACPPQTSCLGPILG---PGQS---WSG-AKVAAPWG------TSGASGIHSSLEQIVP-----------------------QTSLGNLSDLIYTSAIVTNVDHF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HB31-1", "uniprot_id": "SEBOX_HUMAN", "id": "Q9HB31-1", "name": "Homeobox protein SEBOX", "aln": "--------------------------------------------------------------------------------------------------------------MPSPVDASSADGGSGL------------------------GSHRRKRTTFSKGQLLELERAFAAWPYPNISTHEHLAWVTCLPEAKVQVWFQKRWAKI------IKNRKSGILSPGSECPQSSCSLPDTL-----------------------QQPWDPQMPGQP--------------PPS---------SGTPQRTSVCR-HSSCPAPGLS---PRQG---WEG-AKAVAPWG------SAGASEVHPSLERATP-----------------------QTSLGSLSDLIYALAIVVNVDHS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JJ26-1", "uniprot_id": "SEBOX_DANRE", "id": "Q8JJ26-1", "name": "Homeobox protein SEBOX", "aln": "--------------------------------------------------------------------------------MALFYDQSFDLGLVQKINMETESDFIFNTNMLQFTDVTTKHMLSSPELDRTG---------------HVEGQRKRKRTIFSRAQLSELERAFMITPYPDITLRERLAALTLLPESKIQVWFQNRRARS------MKSKKLITPVSR-RSPAKDCTFPATHPDLNLEQSPEANKSLRHHQQSLIRQALNPWPQNRP--------------PISPDLPEILQWANRNSETPGDSSFSSCPSERIQHPFPNQSSSVWQMNCFAAHPEGLKSYCTTSQALYSSVSVDQMIPAHPSSLEEALQR----QALTHYPQTSLGDISDLIYKAAVVTNLEEC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2P8-1", "uniprot_id": "Q9W2P8_DROME", "id": "Q9W2P8-1", "name": "", "aln": "MMTTTTSQHHQHHPIMPPAMRPAPVQESPVSRPRAVYSIDQILGNQHQIKRSDTPSEVLITHPHHGHPHHIHHLHSSNSNGSNHLSHQQQQQHSQQQHHSQQQQQQQQLQVQAKREDSPTNTDGGLDVDNDDELSSSLNNGHDLSDMERPRKVRRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLAMRLDLSEARVQVWFQNRRAKWRKREKFMNQDKAGYLLPEQGLPEFPLGIPLPPHG--LPGHPGSMQSEFWPPHFALHQHFNPAAAAAAGLLPQHLMAPHYKLPNFHTLLSQYMGLSNLNGIFGAGAAAAAAAASAGYPQNLSLHAGLSAMSQVSPPCS-NSSPRESPKLVPHPTPPHATPPAGGNGGGGLLTGGLISTAAQSPNSAAGASSNASTPVSVVTKGED-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :. .. :*.** *: ** :***.* **:: :* ** *.*:::*****:* *: ::. * . * :* . : :* . . . ::. . . . . . * . : : * ::: * *: ::*.: :. ", "identical_positions": 33, "similar_positions": 52, "identity": "7.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021206-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43865-1", "uniprot_id": "SAHH2_HUMAN", "id": "O43865-1", "name": "S-adenosylhomocysteine hydrolase-like protein 1", "aln": "-MSMPDAMPLPGVGEELKQAKEIED-AEKYS--------------------FMATVTKAPKKQIQFAD--DMQEFTKFPTKTGRRSLSRSISQSSTDSYSSAASYTDSSDD--EVSPREKQQTNSKGSSNFCVKNI-KQAEFGRREIEIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80SW1-1", "uniprot_id": "SAHH2_MOUSE", "id": "Q80SW1-1", "name": "S-adenosylhomocysteine hydrolase-like protein 1", "aln": "-MSMPDAMPLPGVGEELKQAKEIED-AEKYS--------------------FMATVTKAPKKQIQFAD--DMQEFTKFPTKTGRRSLSRSISQSSTDSYSSAASYTDSSDD--EVSPREKQQTNSKGSSNFCVKNI-KQAEFGRREIEIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B5DFN2-1", "uniprot_id": "SAHH2_RAT", "id": "B5DFN2-1", "name": "S-adenosylhomocysteine hydrolase-like protein 1", "aln": "-----------------------------------------------------------------------MQEFTKFPTKTGRRSLSRSISQSSTDSYSSAASYTDSSDD--EVSPREKQQTNSKGSSNFCVKNI-KQAEFGRREIEIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8N1TYR5-1", "uniprot_id": "A0A8N1TYR5_DANRE", "id": "A0A8N1TYR5-1", "name": "", "aln": "MTDCGEDAKLEATKQASKEFKESENVAEKYSAMTATKHSDVNMNVGELSAAFTAVPTHKSVKKIQFANQEDKQEFSKFPTKTGRRSLSRSISQSSTDSYSSAASYTDSSDD--ETSPREKSQVNSKGSSDFCVKNI-KQAEFGRREIEIAEQDMSALISLRKRAQGEKPLAGAKVAGCTHITAQTAVLIETLVALGAQCRWTACNIYSTQNEVAAALAESGVSVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPSVFKKVRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVCGYGEVGKGCCSALKALGAIVCVTEIDPICALQACMDGFRVVKLNEVVRQMDMVITCTGNKNVVTREHLDRMKNGCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHVIWPDGKRVILLAEGRLLNLSCSTVPSFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPNFDAHLTELSDEQAKYMGLNKNGPFKPNYYRY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P50245-1", "uniprot_id": "SAHH3_DROME", "id": "P50245-1", "name": "Adenosylhomocysteinase-like 2", "aln": "MAKMPETTFADLSLAD------------------------------------------------------------KTAVKKSS-IEARRFSDVSTCSFSSTC-FTGSSDE-EDVSPKDNHQRNSAGGTDFCVKSI-SKSAFGRREIEIAESEMPGIMTLRKRAKDEKPLKGANIVGCTHVNAQSAVLIETLVQLGATVRWAACNIYSTQNAVAAALAEAGIPIFAWRGETEEEFWWCLDRAIYSDGWQPNLILDDGGDATHLMLKKYPDYFKAIRGIVEESVTGVHRLYMLSKGGKLTVPAINVNDSVTKNKFDTFYTCRDSILDSLKRTTDIMFGGKQVVICGYGDVGKGCAQSLKGQGCIVYVTEVDPICALQAAMDGFRVVRLNEVIRTVDVVVTATGNKNVITRDHMNRMKNGCILCNMGHSCSEIDVNGLHTPELTWERVRSQVDHIRWPDGRMIILLAEGRLVNLSCSTISSFVVSVASSTQALALIELFSAP-GRYKSDVYLLPKKMDEYVASLHLATFDAHLTELTDEQSKFMGLNKAGPFKANYYRY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZX9-1", "uniprot_id": "SAHH2_DROME", "id": "Q9VZX9-1", "name": "Adenosylhomocysteinase-like 1", "aln": "MNNLADTVVVDPGFGGGDKQQQAGPAPQDAS----------------------VVVPPPATKQ-------------SSALKKTSRYRSRSLSASSTDSFSSAS-YTGSSEDGDDVPPREKVQKNSKGSSDFCVRNIGAQHAFGRREIEIAEQEMPGIIALKKRAAEDKPLKDAKIVGCTHINAQTAVLIETLVELGASVRWAACNIYSTQNEVAAALAESGIPIFAWRGETEEDFWWCIDRCVNAENWQPNMILDDGGDATHLMLKKYPTMFKLVKGIVEESVTGVHRLYQLSKAGKLTVPAMNVNDSVTKTKFDNLYSCKESILDSLKRSTDVMFGGKQVVVCGYGDVGKGCAQALKGQGCIVYITEIDPICALQASMDGFRVVKLNEVIRNVDIVVTATGNKNVVVREHMDKMKSGCIVCNMGHSNTEIDVNGLRTPDLTWEKVRSQVDHIIWPEGKYIILLAEGRLVNLSCSSIPSFAVSITSATQALALIELFNAPPGRYKSDVYLLPKKMDEYVASLHLPTFDAHLTELSDEQAKYMGLNKAGPFKPNYYRY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . *. :* :* ** *:**:. :*.**:: :..*::: * ** *.::***:.* : **********.:*..:::*:*** :*** .*::.****:.**:******* *** **:********* *******:*:.:***:**:*::****:**.: :.**.*:******* ** : **** ** ::************** ***.*** ***:******** ***.:* *::****.***:**:********:****:*****. :**. *.** :**:********.*******:****:* :*:*:*.******:.*:*:::**..**:****** :**** .*:**:****:*******: **:*: ::*******:*****::.:*.:*::::*********:.** ****.******************..********:*:*:*::**** ****.*****", "identical_positions": 306, "similar_positions": 124, "identity": "54.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021206-9", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P00742-1", "uniprot_id": "FA10_HUMAN", "id": "P00742-1", "name": "Coagulation factor X", "aln": "MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEA--------PDSITWKPYDAADLD-PTENPFDLLDFNQTQ-----PERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVI----TSSPLK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88947-1", "uniprot_id": "FA10_MOUSE", "id": "O88947-1", "name": "Coagulation factor X", "aln": "MGSPVQLSLLCVVLASLLLPGKGVFINRERANNVLARTRRANSFFEEFKKGNLERECMEEICSYEEVREIFEDDEKTKEYWTKYKDGDQCESSPCQNQGACRDGIGGYTCTCSEGFEGKNCELFVRKLCRLDNGDCDQFCREEQNSVVCSCASGYFLGNDGKSCISTAPFPCGKITTGRRKRSVALNTSDS-----------ELDLEDALLDEDFLS-PTENPIELLNLNETQ-----PERSSDDLVRIVGGRECKDGECPWQALLINEDNEGFCGGTILNEFYILTAAHCLHQARRFKVRVGDRNTEKEEGNEMVHEVDVVIKHNKFQRDTYDYDIAVLRLKTPITFRMNVAPACLPQKDWAESTLMTQKTGIVSGFGRTHEKGRQSNILKMLEVPYVDRNTCKLSTSFSITQNMFCAGYEAKLEDACQGDSGGPHVTRFKNTYYVTGIVSWGEGCARKGKYGIYTKVTTFLKWIDRSMKARVGPTAETPR--------TAGPPN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QLC3-1", "uniprot_id": "F1QLC3_DANRE", "id": "F1QLC3-1", "name": "coagulation factor Xa", "aln": "MS---WVFWNFISLFVTHSVCAEVFLNTRDANQVLIRQRRANSLFEEMKKGNMERECIEERCNYEEAREIFEDVKKTDEFWHKYVDGDACLSHPCVNGGQCKDAIGPYTCFCQQGFKGYNCEIVIPELCENENGGCDHFCEVMEKNVVCSCANGYELAPNGKSCQSQDPFKCGVIYP-KKTRSIFFHTPNITESENEEETELEATIEPVYNHSNPLNNQTDSMFGLHELEIIEEEPILPVVSTAGDGRIVNGVECPPGDCPWQALLINENNMGFCGGTILTEHFILSAAHCMNESLSIRVVVGEYDTLVPEGREATHDVDEILIHKNYQPDTYHNDIALIKLSKPIKFTKYIIPACLPEMKFAERVLMQQDDGLVSGFGRVREGGLSSTILQKLTVPYVNRAKCIESSNFKISGRMFCAGYDQEEKDACQGDSGGPHVTRFKNTWFITGVVSWGEGCARKGKYGVYTQVSKYIMWINNAMTKVMPETGASLKPKAKRELRHKTPIRRV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : * :*:. . **::* * ****::**:***::****:** *.***.**:*** .**.*:* ** *** * : ** * * *:*.:* *** * :**:* ***:. :** :**.**:**. ::.****** ** *. :**:* . *: ** ::.**: *.. : . *. *:. : * ::: : * . . ***.* ** *:**********:* ********.*.:**:****: :: ::* **: :* ** * .*:*: :: *:.: :**. ***:::*..**.* : *****: .:** .** *. *:******.:* * .*. *: * ****:* .* *:.* *: .******: : :****************:*:::**:**************:**:*: :: **:.:*. .. : * . ", "identical_positions": 217, "similar_positions": 128, "identity": "42.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021210-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JU49-1", "uniprot_id": "A0A0G2JU49_RAT", "id": "A0A0G2JU49-1", "name": "Metaxin-1", "aln": "MRLGGPPRNVRSGQRFERSRCSRGHVQFGKSPQRPLSRTRCPSSKPCLSPAVRGYARQRHRESPKRAWTAALLPYGGRLRTSPRRSS-EGQCSTSSSAAASPAARSHASLDLK---LRVATQAETRGCSSWREKADAYERVLPGQRMCKMAAPMELFCWSGGWGLPSVDLDSLAVLTYTRFTC--------APLKVHKISNPWQSPSDLFNIFSILGTLPALRTSSGKVITEPHKIITHLRK----------EKYNADYDLSARQG-ADTLAFISLLEEKLLPMLIHTFWIDAKNYVEVTRKWYAEAMPFPLNFFLPGRMQRRHMERLQLLCGEHRLESEEELE-KELYQEARECLTLLSHRLGSRKFFFGDAPASLDAFVFSHLVLLLQAKLPSGKLQAHLRGLQNLCVYCTHILNLYFPRDATDVPPPPCQTP--AGP-ETEEEPYRRRTQILSVLAGLAAMVGYALLSGIVSIQRASPARAPCTQALDLAEEDEED----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47802-1", "uniprot_id": "MTX1_MOUSE", "id": "P47802-1", "name": "Metaxin-1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MAAPMELFCWSGGWGLPSVDLDSLAVLTYTRFTG--------APLKIHKTSNPWQSPS---------GTLPALRTSDGKVITVPDKIITHLRK----------EKYNADYDLSARQG-ADTLAFMSLLEEKLLPVLIHTFWIDAKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQYMERLQLLCGEHKSENEEELE-KELYQEARECLTLLSQRLGSQKFFFGDAPASLDAFVFSHLALLLQAKLPSGKLQAHLRGLHNLCAYCTHILNLYFPRDGDEVP-LPRQTP--AAP-ETEEEPYRRRTQILSVLAGLAAMVGYALLSGIVSIQRTSPARAPGTRALGLAEEDEED----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13505-1", "uniprot_id": "MTX1_HUMAN", "id": "Q13505-1", "name": "Metaxin-1", "aln": "MLLGGPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPRSPEPAAPSGVRGSTWTRRRDSPRRAGPTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSLASPGISPGPLTATIGGAVAGGGPRQGRAEAHKEVFPGQRVGKMAAPMELFCWSGGWGLPSVDLDSLAVLTYARFTG--------APLKVHKISNPWQSPS---------GTLPALRTSHGEVISVPHKIITHLRK----------EKYNADYDLSARQG-ADTLAFMSLLEEKLLPVLVHTFWIDTKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQYMERLQLLTGEHRPEDEEELE-KELYREARECLTLLSQRLGSQKFFFGDAPASLDAFVFSYLALLLQAKLPSGKLQVHLRGLHNLCAYCTHILSLYFPWDGAEVP-PQRQTP--AGP-ETEEEPYRRRNQILSVLAGLAAMVGYALLSGIVSIQRATPARAPGTRTLGMAEEDEEE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PR98-1", "uniprot_id": "A0A8M9PR98_DANRE", "id": "A0A8M9PR98-1", "name": "Metaxin", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MAAPLELFCWKGDYGLPSVDVDCLAVLAYAKFAG--------APIKVHKITNPWRSPT---------GSLPALKTREEGSISQPSKIIIHLRK----------QKYNADYDLSAKEG-ADTLAFVSLLEEKLLPALVYTLWIDSKNYVDVTRCWYAENIPFPLNFLLPNRMHSQQLEKLRLVRGDPVLEPGEQLE-KELYRDAFECMTLLSQRLGSQKFFFGDSPSSLDAYVFAHLAPLLKIKLPNGKLQQHLNSLNNLEQFCSNILLLYFPSDQREAPARKIHVQ--SDSSDFDNEPHMRRNQILSVLFAVGAMLGYAVLTGIITIKRERPQLKNSSHED--GDEEDED----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHB6-1", "uniprot_id": "MTX1_DROME", "id": "Q9VHB6-1", "name": "Metaxin-1 homolog", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MEMQLGAMLYVYKGEYGLPSIDFECLRALCLLRFTR--------CPMDVQTSSNPLRSGA---------GKLPYLQIGNQK-FAGYRQIKRVLDL----------EGYPIDAHLSTKQK-HLSTAYANWVFTNLHAYYHYFLFGEPHNFDTTTRGLYAKRTPFPFNFYYPSSYQREACDVVQVMAGFDVNDKLDKHEGDYLVVNAKKVVNLLSRKLGRKVWFFGDTYSEFDAIVYSYLAIIFKIALPNNPLQNHIKGCQNLVNFINRITKDIFRIEGYSSVKLTKTPSGTEASLTASERKFLDSELNTKIVAGVGAVLAMGAFAAWRGIYNQLTTRSSTDYDGIDYEDDEMEEGLD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50110-1", "uniprot_id": "SAM37_YEAST", "id": "P50110-1", "name": "Sorting assembly machinery 37 kDa subunit", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MVKGSVHLWGKDGKASLISVDSIALVWFIKLCTSEEAKSMVAGLQIVFSNNTDLSSD---------GKLPVLILDNGTKVSGYVNIVQFLHKNICTSKYEKGTDYEEDLAIVRKKDRLLEYSLLNYVDVEISRLTDYQLFLNTKNYNEYTKKLFSKLLYFPMWYNTPLQLRSQARENCEEIIGSLTLEDDEEFVESKAMESASQLAQSKTFKIAHKNKIKGK--QELQQVKYN---LQFDNRLQS-CVSNWLAARKKLDDSVILSSDLLFLANLYVQLGLPDGNR---------IRSKLEQTFGSELLNSMSNKIDDFVHRPSNNLEQRDPQFREQGNVVMSLYNLACKYI--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : . :..:.: : :: . :.: .*. * *.** * .: :* * * * : :: : . : :: : :: :.:*: *: ::: **: : * : . : . : * : :: . .* : : ::. : : *. .:: : :. * . :. : . ::* * : . .:: .:. : : . . : . ", "identical_positions": 21, "similar_positions": 89, "identity": "4.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021210-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3YTP3-1", "uniprot_id": "D3YTP3_MOUSE", "id": "D3YTP3-1", "name": "Metaxin", "aln": "--MAAPMELSCWGGGWGLPSVHSESLVVLAYAKFSGAPLKINIIDNTWRGSRGDVPILTTEDSIVSKPAKILNFLRKQKYNADCELSAKQGADTLAYIALLEEKLLPAVLHTFWVENENYFTVTKPWFASRIPFPLSLILPGRMSRGALNRILLTRGEPPLYHVQEVEAQ-IYRDARECLNLLSNRLGTSQFFFGDTPSTLDAYVFGFLAPLYKVSFPKVHLQKHLKQLCNLCRFCDDILDSYFRPGPGG----VSP-AGQEMVDANLQKLTQLVNKESNLIEKMDGNLRQSPQLLPRKLPTLKLTPAEEESNSLQLLSP-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LPS2-1", "uniprot_id": "A0ABK0LPS2_RAT", "id": "A0ABK0LPS2-1", "name": "Metaxin", "aln": "--MAAPMELSCWGGGWGLPSVHSESLVVLAYAKFSGAPLKVNIIDNTWRGPRGDVPILTTEDSIVSKPEKILNFLRKQKFNADCELSAKQGADTLAYIALLEEKLLPGVLHTFWVENDNYFTVTKPWFASRIPFPLSLILPGRMSRGALNRILLTRGVPPLYHVQDVEAQ-IYRDAKECLNLLSNRLGTSQFFFGDTPSTLDAYVFGFLAPLYKVRFPKVHLQEHLKQLPNLCRLCDDILDSYFRHGAGG----ISP-AGQE-VDANLQKLTQLVNKESNLIEKMDGNLRQSPQLLPRKLPTLKLTPAEEESNSSQLLSP-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5HYI7-1", "uniprot_id": "MTX3_HUMAN", "id": "Q5HYI7-1", "name": "Metaxin-3", "aln": "--MAAPLELSCWGGGWGLPSVHSESLVVMAYAKFSGAPLKVNVIDNTWRGSRGDVPILTTEDDMVSQPAKILNFLRKQKYNADYELSAKQGADTLAYIALLEEKLLPAVLHTFWVESDNYFTVTKPWFASQIPFPLSLILPGRMSKGALNRILLTRGQPPLYHLREVEAQ-IYRDAKECLNLLSNRLGTSQFFFGDTPSTLDAYVFGFLAPLYKVRFPKVQLQEHLKQLSNLCRFCDDILSSYFRLSLGG----ISP-AGQETVDANLQKLTQLVNKESNLIEKMDDNLRQSPQLPPRKLPTLKLTPAEEENNSFQRLSP-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4VBW0-1", "uniprot_id": "MTX3_DANRE", "id": "Q4VBW0-1", "name": "Metaxin-3", "aln": "--MAEPIELLCWGGDWDLPSVQTDSLTVLAYAKFAGAELTVKFVDWTWRTITASVPQIHYEGTTVTEPTQILNFLRKQRFNADFELTAKQGADTMAYIALLEEKLRPALLHTFWVDAENYANLTRPWFTSHSPFPLNFFVPGRQASLALSRILLTKAESPLLNITEVEGK-IYSEAKECLNLLSHRLGNFNFFFGDTPTSLDAFVFGHIAPLIKAPLPSGQLQKHLNQLDNLCQFCNTILKNYFTDATAEKRMDCSPTVAHDPVDANLQKLTQLVNKESNLIEKMDDNLRSSPQHRPHRHEAKPSAPASDRNSTPA-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHB6-1", "uniprot_id": "MTX1_DROME", "id": "Q9VHB6-1", "name": "Metaxin-1 homolog", "aln": "MEMQLGAMLYVYKGEYGLPSIDFECLRALCLLRFTRCPMDVQTSSNPLRSGAGKLPYLQIGNQKFAGYRQIKRVLDLEGYPIDAHLSTKQKHLSTAYANWVFTNLHAYYHYFLFGEPHNFDTTTRGLYAKRTPFPFNFYYPSSYQREACDVVQVMAGFDVNDKLDKHEGDYLVVNAKKVVNLLSRKLGRKVWFFGDTYSEFDAIVYSYLAIIFKIALPNNPLQNHIKGCQNLVNFINRITKDIFRIEGYSSVKLTKTPSGTEASLTASERKFLDSELNTKIVAGVGAVLAMGAFAAWRGIYNQLTTRSSTDYDGIDYEDDEMEEGLD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : * :.***:. :.* .:. :*: . : :: . . * ..:* : . .: :* ..* : : * .*::** : ** : :* . : :: : .*: . *: ::.: ***:.: *. * . : : . :: . *.. : :*:: :****.:** :***** : :** *:..:* : * :*. **:*:: ** .: : * .. * .. . : : :: : ::::: :. * .. : : :. . ", "identical_positions": 53, "similar_positions": 109, "identity": "16.21%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021211-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64339-1", "uniprot_id": "ISG15_MOUSE", "id": "Q64339-1", "name": "Ubiquitin-like protein ISG15", "aln": "MAWDLKVKMLGGNDFLVSVTNSMTVSELKKQIAQKIGVPAFQQRLAHQTA---VLQDG-LTLSSLGLGPSSTVMLVVQNCSEPLSILVRNERGHSNIYEVFLTQTVDTLKKKVSQREQVHEDQFWLSFEGRPMEDKELLGEYGLKPQCTVIKHLRLRGGGGDQCA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05161-1", "uniprot_id": "ISG15_HUMAN", "id": "P05161-1", "name": "Ubiquitin-like protein ISG15", "aln": "MGWDLTVKMLAGNEFQVSLSSSMSVSELKAQITQKIGVHAFQQRLAVHPSG-VALQDR-VPLASQGLGPGSTVLLVVDKCDEPLSILVRNNKGRSSTYEVRLTQTVAHLKQQVSGLEGVQDDLFWLTFEGKPLEDQLPLGEYGLKPLSTVFMNLRLRGGGTEPGGRS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BHB8-1", "uniprot_id": "A2BHB8_DANRE", "id": "A2BHB8-1", "name": "", "aln": "--MQLTVKLLGGDVKRLEVSGDATVGILKQVISQYFNVPTFKQKLSAENGQRISLEDESRTLSSYGLNSDSVVMLLITTNPGTFQVFVKNEKGQVKTYDVDANETVDQLQTKIYQKERVPKDQQRLIFKGRQLESGMKLQDYDITSLSTIHMTLRLRGG--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.**:*.*: :.::.. :*. ** *:* :.* :*:*:*: . . *:* .*:* **...*.*:*:: . .:.::*:*::*: . *:* .:** *: :: * * .* * *:*: :*. * :*.:.. .*: ****** ", "identical_positions": 47, "similar_positions": 61, "identity": "28.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021211-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35763-1", "uniprot_id": "MOES_RAT", "id": "O35763-1", "name": "Moesin", "aln": "-MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKAFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERALLENEKKKRELAEKEKEKIEREKEELMEKLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLASEMAELTARVSQLEMARKKKESEAEECHQKAQMVQED---LEKTRAELKTAMSTPHVAEPAE--NEHDE---QDENGAEASAELRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTTNDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26041-1", "uniprot_id": "MOES_MOUSE", "id": "P26041-1", "name": "Moesin", "aln": "-MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKAFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERALLENEKKKRELAEKEKEKIEREKEELMEKLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLASEMAELTARISQLEMARKKKESEAVEWQQKAQMVQED---LEKTRAELKTAMSTPHVAEPAE--NEHDE---QDENGAEASAELRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P26038-1", "uniprot_id": "MOES_HUMAN", "id": "P26038-1", "name": "Moesin", "aln": "-MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQED---LEKTRAELKTAMSTPHVAEPAE--NEQDE---QDENGAEASADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66I42-1", "uniprot_id": "MOESA_DANRE", "id": "Q66I42-1", "name": "Moesin a", "aln": "-MPKTISVRVTTMDAELEFAIQPSTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQEATQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQAKYADYNKDAHTPGYLSNEKLLPQRVLEQHKLNKEQWEERIQVWHEEHKGMLREDSMMEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDKMTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAQRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAKEEKNHKKMERALLEDERKKREQAEKEKEKIEKEKEELMERLRVIEEQTRKAQQELEEQTRKALELEQERKRAQEEAERLERERRLAEEAKSALLQQSESQMKNQEHLATELAELTSKISLLEDAKKKKEDEALEWQTKATMVQED---LEKTKEELKNKVMSSHVTEPVHGENDNDE---GDESSAEASAELTSAAAYKDRSEEERMTEAEKNERVQKHLLALTSELANARDETKKTQNDIIHAENVRAGRDKYKTLRQIRSGNTKQRIDEFECM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P46150-1", "uniprot_id": "MOEH_DROME", "id": "P46150-1", "name": "Moesin/ezrin/radixin homolog 1", "aln": "MSPKALNVRVTTMDAELEFAIQSTTTGKQLFDQVVKTIGLREVWFFGLQYTDSKGDSTWIKLYKKVMNQDVKKENPLQFRFRAKFYPEDVAEELIQDITLRLFYLQVKNAILTDEIYCPPETSVLLASYAVQARHGDHNKTTHTAGFLANDRLLPQRVIDQHKMSKDEWEQSIMTWWQEHRSMLREDAMMEYLKIAQDLEMYGVNYFEIRNKKGTDLWLGVDALGLNIYEQDDRLTPKIGFPWSEIRNISFSEKKFIIKPIDKKAPDFMFFAPRVRINKRILALCMGNHELYMRRRKPDTIDVQQMKAQAREEKNAKQQE-------REKLQLALAARERAEKKQQEYEDRLKQMQEDMERSQRDLLEAQDMIRRLEEQLKQLQAAKDELELRQKELQAMLQRLEEAKNMEAVEKLKLEEEIMAKQMEVQRIQDEVNAKDEETKRLQDEVEDARRKQVIAAEAAAALLAASTTPQHHHVAEDENENEEELTNGDAGGDVSRDLDTDEHIKDPIED-RRTLAERNERLHDQLKALKQDLAQSRDETKETANDKIHRENVRQGRDKYKTLREIRKGNTKRRVDQFENM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **::.***************..************************** *:*. ***:** *** ***:**.** *:**********:*****: * ***:****:.**.*:*******:*********:::.*.** .*..*:*:.::******::***:.*::**: * .* :**:.*****:::*****************.*:****::***************:*::****************.:***:***********:*:* *:**************************:********:***: *: * ::* : * :*: *::::* ::*: ::*: .::*::* * .**:: *: * :.* .:: : . * : .. : : :* *: .:. :: : *:.*: . : :. .:.. :: * :.: . .. *:::* .: ..:.* :* : ** *: * * **:***::.:* **..:**::***:*:* ** ** **:* *********:**.****:*:*:** *", "identical_positions": 312, "similar_positions": 156, "identity": "53.24%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021211-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6HA08-1", "uniprot_id": "ASTL_HUMAN", "id": "Q6HA08-1", "name": "Astacin-like metalloendopeptidase", "aln": "MEGVGGLWPWVLGLLSLPGVILGAPLASSCAGACGTSFPDGLTPEGTQASGDKDIPAINQGLILEETPESSFLIEGDIIRPSPFRLLSATSN--KWPMGGSGVVEVPFLLSSKYDEPSRQVILEALAEFERSTCIRFVTYQDQRDFISIIPMYGCFSSVGRSGGMQVVSLAPT-CLQKGRGIVLHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSQSSNMLTPYDYSSVMHYGRLAFSRR-GLPTITPLWAPSVHIGQRWNLSASDITRVLKLYGCSPSGPRPRGRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLSAEASARQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGSPALPGGCVPRNHFKGMSED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LW01-1", "uniprot_id": "HE12_DANRE", "id": "Q1LW01-1", "name": "Hatching enzyme 1.2", "aln": "MD--------IRASLSILLLLFGLSQASPLR-----EFEAIFVSEPETVDITTQILETNKG-------SSEVLFEGDVVLPKNRNALICEDKSCFWKKNANNIVEVPYVVSGEFSINDKSVIANAISIFHAQTCIRFVPRSIQADYLSIENKDGCYSAIGRTGGKQVVSLNRKGCVYSG--IAQHELNHALGFYHEQSRSDRDQYVRINWNNISPGMAYNFLKQKTNNQNTPYDYGSLMHYGKTAFAIQPGLETITPIPDENVQIGQRQGLSKIDILRINKLYGC------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : . **: :::* . **. .* :..* .. .:* *:* .*..*:***:: *. . * . .: * ....:****:::*.::. .:.** :*:: *. .******. . * *::** **:*::**:** ***** . *: .* *. *** *.***:**::*:***:*:*:***:* **: **:*.::.* *****.*:****: **: : ** ****: .*:**** .** ** *: ***** ", "identical_positions": 111, "similar_positions": 86, "identity": "25.52%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021212-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZX56-1", "uniprot_id": "D3ZX56_RAT", "id": "D3ZX56-1", "name": "ATP-dependent RNA helicase", "aln": "MEHVTEGSWESLQVP-LHPLVLGALRELGFLHMTPVQSATIPLFMRNKDVAAEAVTGSGKTLAFVIPILEILLRR---EEKLKKNQVGAIVITPTRELAIQIDEVLSHFTKH----FPQFSQILWIGG--RNPGEDVERFKQHGGNIIVATPGRLEDMFRRKAEGLDLASYVKSLDVLVLDEADRLLDMGFEASINTILEFLPKQRRTGLFSATQTQEVENLVRAGLRNPVRISVKEKGVAASSTQKTPSRLENHYMICKADEKFNQLVHFLRS--RQQEKHLVFFSTCACVEYYGKALEALVQR------VKILCIHGKMKY-KRNKIFMEFRKLQS-GILVCTDVMARGIDIPEVNWVLQYDPPSNASAFVHRCGRTARIGHGGSALVFLLPMEEAYINFLAINQKCPLQEMS---------LQRNTVDLLPKLRAMALADRAVFEKGMKAFVSFVQAYAKHECSLIFRLKDLDFAGLARGFALLRMPRMPELKGKQ--------FPDFVP--VDIDTDTIPFKDKIREKQRQKLLE-----------QKRKERTENEGRRKFIKNKAWSKQ---KAKKERKKKMNAKR----KKDEGSDIDDEDMEELLNDTRLLKKFKKGKITEEEFEKGLLTSTKRTVRLTESGVSDSEEDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZPL9-1", "uniprot_id": "DDX55_MOUSE", "id": "Q6ZPL9-1", "name": "ATP-dependent RNA helicase DDX55", "aln": "MEHVTEGAWESLQVP-LHPRVLGALRELGFPHMTPVQSATIPLFMKNKDVAAEAVTGSGKTLAFVIPILEILLRR---EEKLKKNQVGAIVITPTRELAIQIDEVLSHFTKH----FPQFSQILWIGG--RNPGEDVERFKQHGGNIIVATPGRLEDMFRRKAEGLDLASCVKSLDVLVLDEADRLLDMGFEASINTILEFLPKQRRTGLFSATQTQEVENLVRAGLRNPVRISVKEKGVAASSTQKTPSRLENHYMICKADEKFNQLVHFLRS--RQQEKHLVFFSTCACVEYYGKALEALLKK------VKILCIHGKMKY-KRNKIFMEFRKLQS-GILVCTDVMARGIDIPEVNWVLQYDPPSNASAFVHRCGRTARIGHGGSALVFLLPMEEAYINFLAINQKCPLQEMS---------LQRNTIDLLPKLRAMALADRAVFEKGMKAFVSFVQAYAKHECSLIFRLKDLDFAGLARGFALLRMPRMPELRGKQ--------FPDFVP--VDIDTDTIPFKDKIREKQRQKLLE-----------QKRKERSENEGRKKFIKNKAWSKQ---KAKKERKKKMNAKR----KKDEGSDIDDEDMEELLNDTRLLKKFKKGKITEEEFEKGLLTSAKRTVQLTDLGVSDLEEDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NHQ9-1", "uniprot_id": "DDX55_HUMAN", "id": "Q8NHQ9-1", "name": "ATP-dependent RNA helicase DDX55", "aln": "MEHVTEGSWESLPVP-LHPQVLGALRELGFPYMTPVQSATIPLFMRNKDVAAEAVTGSGKTLAFVIPILEILLRR---EEKLKKSQVGAIIITPTRELAIQIDEVLSHFTKH----FPEFSQILWIGG--RNPGEDVERFKQQGGNIIVATPGRLEDMFRRKAEGLDLASCVRSLDVLVLDEADRLLDMGFEASINTILEFLPKQRRTGLFSATQTQEVENLVRAGLRNPVRVSVKEKGVAASSAQKTPSRLENYYMVCKADEKFNQLVHFLRN--HKQEKHLVFFSTCACVEYYGKALEVLVKG------VKIMCIHGKMKY-KRNKIFMEFRKLQS-GILVCTDVMARGIDIPEVNWVLQYDPPSNASAFVHRCGRTARIGHGGSALVFLLPMEESYINFLAINQKCPLQEMK---------PQRNTADLLPKLKSMALADRAVFEKGMKAFVSYVQAYAKHECNLIFRLKDLDFASLARGFALLRMPKMPELRGKQ--------FPDFVP--VDVNTDTIPFKDKIREKQRQKLLE-----------QQRREKTENEGRRKFIKNKAWSKQ---KAKKEKKKKMNEKR----KREEGSDIEDEDMEELLNDTRLLKKLKKGKITEEEFEKGLLTTGKRTIKTVDLGISDLEDDC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JHJ2-1", "uniprot_id": "DDX55_DANRE", "id": "Q8JHJ2-1", "name": "ATP-dependent RNA helicase DDX55", "aln": "MENITDGKWGSLPVK-LHDNILQTLKELGFTYMTPVQSACIPLFMSNKDVAAEAVTGSGKTLAFVIPALEILLKR---EEKLKKMQVGALIITPTRELAMQISEVMGRFLQG----FPQFTQILLIGG--SNPIEDVEKLKTQGANIIIATPGRLEDMFRRKADGLDLATAVKSLDVLVLDEADRLLDMGFEASLNTILGYLPKQRRTGLFSATQTQELEKLVRAGLRNPVRITVKEKGVAASSVQKTPAKLSNYYTMCRAEEKFNTLVAFLRQ--HKHEKQLVFFSTCACVEYFGKALEVLVKN------VSIHCIHGKMKH-KRNKIFADFRALKS-GILVCTDVMARGIDIPEVNWVLQYDPPSSASSFVHRCGRTARIGNQGNALVFLLPMEESYVNFLSINQKCPLQSFS---------SVKDVVDVLPKLKAMALGDRAMFEKGMRAFVSYVQAYAKHECSLIFRIKDLDFAALARGFALLRLPKMPELRGKT--------FPDFKA--EAIDTDTIRFKDKNREKQRQKWLA-----------EQKEK--EVPLRKNFIKNKAWSKQ---KIKKDRKKKRLPKA----KLDQDSDAAEEDLNELMNDTRLLKKLKKGKITEEDFDKQMSSTDKHKP----AGIDSSDGD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHU1-1", "uniprot_id": "DDX55_DROME", "id": "Q9VHU1-1", "name": "Probable ATP-dependent RNA helicase DDX55 homolog", "aln": "---MSRKKWSSLDKPPLSDAVLQVVQSFGFQQMTPVQTAAIPLLLARKDVSAEAVTGSGKTLAFLVPMLEILQRRHK-ETPWGPKEIGALVISPTRELARQISEVLAQFLEHE--DLEHLNQQLIVGG--NSIEEDIATLRRETPCILVCTPGRLEDLFQRKGDDLNLAAQVKSLEFLVLDEADRLLDLGFKTSVNNILGYLPRQRRTGLFSATQTTEVTDLIRAGLRNPVLVSVKEK-----ASVNTPARLQNFYRIVEPELKFVALLEFLSSPATVIGKVMVFFPTCACVEYWAEALPPLLPK------RTVLGIHGKMKN-KRANVVEKFRNTPQ-AVLLCTDVLARGLDVPEIEWVVQWDPPSTASSFVHRVGRTARQGNEGNALVFLLPSEDAYVHFLKINQKVELTKLLTEEAEDADREKKKLPAVLDQLHRLQAADKGVYDKGMRAFVSHVRAYTKHECSAILRLKDLDLGKMATAYGLLQLPRMPELKNYQ--------GGGYVAPAFEVDLSKLTYKNAQKEQVRQKKMETYEQTGSWPGQKQHKKRVESWDQTKKAKLDAKSKKELRKAKKQRKKAAEAEASRSGKGKKRQQFSQEDLDELASDIRLFKRLKKNKISEEDFDKAMGIEGNND---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25808-1", "uniprot_id": "SPB4_YEAST", "id": "P25808-1", "name": "ATP-dependent rRNA helicase SPB4", "aln": "--MSKSLEWDNLGFS-LLPWIRTGLDVMGFETMTPVQASTIPMLAGNKDVVVDSVTGSGKTAAFVIPVLEKVVKEEANTSKFKKAHFHSLIIAPTRELSRQIESVVLSFLEHYPSDLFPIKCQLLVGTNEATVRDDVSNFLRNRPQILIGTPGRVLDFLQMP------AVKTSACSMVVMDEADRLLDMSFIKDTEKILRLLPKQRRTGLFSATMRSAGSDIFKTGLRNPVRITVNSK-------NQAPSSLKLNYCVVNPAEKLQLLVSILNN--YKFKKCIVYFPTCVSVSYFYSFIQYLGKRNILVNEVEIFSLHGKLQTSARTKTLTAFTDSLSNSVLFTTDVAARGIDIPDVDLVIQLDPPTNTDMFMHRCGRTGRANRVGKAITFLNEGREEDFIPFMQVKNVELEELD-------LEVKGITTNFYEDFRNWILEDRDRFDKGVKAYVAFIKYYSNHSATSIFRLQSLDYVGIAKLYGLFRLPRMPEITKYLATEKQEGIFPGNWLVDPPVNMDEYKYKDKKREKERQETLKN----------ISLINDKKKLKSELKKKNLAWSDKTLTKERKLERKEKMSLK----RKAIEEELKAEELDENAEEERIKEDWKEIVLQNKRKKVSSKAIQGNFDDL------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * .* * : : :** *****:: **:: .*** .::******* **::* ** : :. .. :::*:*****: **..*: * : : :. * :* . :*: : . *:: ****: *::: * . : ..:*:********:.* . :.** **:********** .:.::****** ::*:.* ::*: *. * : .. *: *: :* . * :*:*.**..*.*: . : * : :***:: * : . * . .:*. *** ***:*:*::: *:* ***:.:. *:** ***.* .. *.*:.** .: . : :: * .: . .:: *: ::**::*:*:.:: *::*... *:*::.** :* :.*:::*:***: . :: . :*: :*: **: : . : : * * *.: * :* .:* : .: *:::* .: *: : *: : :: . . ", "identical_positions": 155, "similar_positions": 185, "identity": "23.59%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021213-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIQ5-1", "uniprot_id": "SDA1_RAT", "id": "Q5XIQ5-1", "name": "Protein SDA1 homolog", "aln": "MSGRN-NNKLPSNLPQLQNLIKRDPPAYVEEFLQQYNHYKSNMEIFKLQ------------------------------PNKPSKELAELVMFMAQIGHCYPEHLSEFPQELKDLLSYNHTVLDPDLRMTFCKALILLRNKNLINPSDLLELFFELLRCRD------------KLLRKTLYTHIVTDIKNINAKHKNNKVNVVLQNFMYTMLRDSNATAAKMSLDVMIELYRRNIWNDAKTVNVITTA-CFSKITKILVAALTFFLGKDEEEKQDSDSESEDDGPTARDLLVQYATG-KKGSKNKKKLEKAMKVLKKQKKK---KKPEVFNFSAIHLIHDPQDFAEKLLKQLESCKER----FEVKMMLMNLISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLFAAQASHHLVPPEIIQSLLLTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGK--------PTEASIEARIQEYGELDAKDYIPGAEVL-------ELEKEENTENDEDGWESASLS---------------EEEE-DGEWVDVHHS---------SDEEQQA----------------VAKKLDSMPM---EERKAKAAAVSTSRVLTQDDFQKIRMAQMKKEMDAAPGKAQKRKYLDMDSDEESRGELLSLRDIERLHKKPKSDKETRLATAMAGRTDRKEFVRKKTKINPFSSSTNKEKKKQKNFMMMRYSQNVRSKTSRSFREKQLALRDALLKKRKRMK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80UZ2-1", "uniprot_id": "SDA1_MOUSE", "id": "Q80UZ2-1", "name": "Protein SDA1 homolog", "aln": "MSGRN-NNKLPSNLPQLQNLIKRDPPAYVEEFLQQYNHYKSNMEIFKLQ------------------------------PNKPSKELAELVMFMAQIGQCYPEHLSNFPQELKDLLSYNHTVLDPDLRMTFCKALILLRNKNLINPSSLLELFFELLRCHD------------KLLRKTLYTHIVTDIKNINAKHKNNKVNVVLQNFMYTMLRDSNATAAKMSLDVMIELYRRNIWNDAKTVNVITTA-CFSKITKILVAALTFFLGKDEEEKQDSDSESEDDGPTARDLLVQYATG-KKGSKNKKKLEKAMKVLKKQKKK---KKPEVFNFSAIHLIHDPQDFAEKLLKQLESCKER----FEVKMMLMNLISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLFAAQASHHLVPPEIIQSLLVTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGK--------PTEASIEARIQEYGELDAKDYIPGAEVL-------ELEKGENTEDDEDGWESASLS---------------EEEEEDGEWVDVHHS---------SDEEQQA----------------IATKLDSMPM---EERKAKAAAISTSRVLTQDDFQKIRMAQMKKEMDAAPGKAQKRKYLEIDSDEESRGELLSLRDIERLHKKPKSDKETRLATAMAGRTDRKEFVRKKTKINPFSSSTNKEKKKQKNFMMMRYSQNVRSKSARSFRDKQLALRDALLKKRKRMK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NVU7-1", "uniprot_id": "SDA1_HUMAN", "id": "Q9NVU7-1", "name": "Protein SDA1 homolog", "aln": "MSNRN-NNKLPSNLPQLQNLIKRDPPAYIEEFLQQYNHYKSNVEIFKLQ------------------------------PNKPSKELAELVMFMAQISHCYPEYLSNFPQEVKDLLSCNHTVLDPDLRMTFCKALILLRNKNLINPSSLLELFFELFRCHD------------KLLRKTLYTHIVTDIKNINAKHKNNKVNVVLQNFMYTMLRDSNATAAKMSLDVMIELYRRNIWNDAKTVNVITTA-CFSKVTKILVAALTFFLGKDEDEKQDSDSESEDDGPTARDLLVQYATG-KKSSKNKKKLEKAMKVLKKQKKK---KKPEVFNFSAIHLIHDPQDFAEKLLKQLECCKER----FEVKMMLMNLISRLVGIHELFLFNFYPFLQRFLQPHQREVTKILLFAAQASHHLVPPEIIQSLLMTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGK--------PTEASIEARVQEYGELDAKDYIPGAEVL-------EVEKEENAENDEDGWESTSLS---------------EEEDADGEWIDVQHS---------SDEEQQE----------------ISKKLNSMPM---EERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRYSQNVRSKNKRSFREKQLALRDALLKKRKRMK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NV26-1", "uniprot_id": "SDA1_DANRE", "id": "Q6NV26-1", "name": "Protein SDA1 homolog", "aln": "MSGRH-NNKLPTNLPQLQNLIKRDPKSYTEEFLQQYRHYQSNVEIFKHQ------------------------------PDKANKDLSELVMFLAQVGHCYLEELSDFPQQLTDLLLNYHTVLESDLRMTFCKALIMLRNKDLVSPTSLLGLFFELLRCHD------------KLLRKTLYTHIVTDIKNINAKHKNNKMNTTLQNFMYTMLRDSNPIAAKISLDVMVELYRRNIWNDAKTVNVITTA-CFSKVTKILVAGLKFFLGKDEDEKKDDDSESEDEGSTARDLMMRYSTG-KKTSKNKKKLEKAMKVLKKHKKK---KKVEVFNFSAIHLIHDPQDFSEKLLKQLESSNER----FEVKIMMMELISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLCAAQSSHQLVPPEIIEPVIMTIANNFVTDRNSGEVMTVGINAIKEVVARCPLSMSEDLLQDLTQYKSHKDKNVVMSARGLIQLFRDLNPKMLTRKDRGR--------PTESSKEAKIHKYGELEAKDYIPGAEVL-------EAEKAEDEE-DEDGWESASMS---------------DDDE-DGEWVNVHHS---------SDDDQAE----------------VAEKLQSIPE---EERKAKAAMVSTSRLLTQDDFKKIRVAQMAKEVGNAPGKGQKRK--NVDSDEEERGELLSLRDIERLHKKPKSDKETRLATAMAGRTDRKEFTKKRGKLNPYASTSNKEKKRKKNFMMMRHSQNVRTKGKRSFREKQIALRDSLLKKRK-FK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KKH3-1", "uniprot_id": "SDA1_DROME", "id": "Q7KKH3-1", "name": "Protein SDA1 homolog", "aln": "MVRPN-NNQLPENLPQLQNLIKRDPESYSDEFHIQYQHFLSLLEVFALN------------------------------PSEENKSLDDIVMFVAQVAQCYPAVCEEFPKRLSDLLKNYATVLDPAMRNCFVKALILLRNKNLVPALDILELFFQLLRCPD------------KNLRTFLQTHIVTDIKNMNAKHKDMKLNSSLQAFMYSMLKDANPKAAKMSADIMIELYKKNIWNDSKTVNVIATVGCFSKVTKVLVTSLKFFLGHDEEDEEE-DTDSENEVDLKGALMANRVNK-KTKKRTKQLAQIKKQAVKAQKKK---KNAPAFNFSGIHLVHNPQGMAEGLFKQLQATNER----FEVKLMHLDVISRLIGIHDLFLFGFYPYITRFLQPHQRQVTRVLQFAAQASHELVPGDIIEPILKTIANNFITERNSSDVMAIGLNATREICMRCPLAMGEDLLQDLAMYKTYKEKSVMMAARSLITLYREQLPALLHKKDRGR--------QTEAQAERKVRAYGEREVHDTVLGAEALLKDSKTIDIESEDDTDSNDGEWVNVAHSDGEGGGADDDEEDEDEDEDDDDEDEDEENS---------NDEENEDEDNSDEGVESGEESAKAKKEKKDMRI---LNQKEAAQELALTRIFTDEDFKRINAANLKKTVTSAR----KR------PLEQDRAEFVKLNSIEMIYKKRKHDKESRLETVQAGRQDRERFGWKDGRVNEHCSKTNREKRKTKNFGMLRH--KARSKVKKSFKDKQQALRKHLLHQKK-MK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53313-1", "uniprot_id": "SDA1_YEAST", "id": "P53313-1", "name": "Protein SDA1", "aln": "MGRRSRAAMLPTNIILLQNLVKRDPESYQEEFLQQYAHYESLRDIFMLNGLAGGDSAAATNGLDVGNGSSTMAGTNGTTMSTSTSQLIELVGFVSQVCSCFPRETANFPSELKQLLLEHHKSLPFELKEKILSCLTMLRNKDVITAEELIQSLFPLLVAYSSHGNSLGVNSHAKELRKIIYTNLISLLKSCNTNGKNQKLNKSTQAVCFNLLDQPD-SQGIWATKLTRELWRRGIWDDSRTVEIMTQA-ALHQDVKIVMSGVMFFLDADREREENFEENSEDEDGFDLDALRHKMQVNKKTGRRGKKLENAIKTVKKKKKNGPGAPQGYLNFSAIHLLRDPQGFAEKLFKEHLSGKTKNKFDMEQKISLMQLLSRLIGTHKLIVLGIYTFFLKYLTPKQRDVTRIMSACAQACHDLVPPEVINVMVRKIADEFVSDGVANEVAAAGINTIREICSRAPLAIDEILLQDLVEYKGSKAKGVNMAAKSLIALYRDVAPEMLKKKDRGKNAAMEVQEAKKGGKDSKRPQFGADNSVQGIAGIELLAKWKK--EHGEESENEDADANWEVDVDS---------------EEDDVDGEWVTMDSDKEYDVDMEDSDDEKDNAKGKESDSDLELSDDDDEKEVKDEQEDADIDPEAAFREIASTRILTPADFAKLQELRNEESVAKIMG----------IHKQDKREELVDASTLTGPIKYKQS-REERLQKVLEGREGRDKFGSRRGKRDNMRSTTNREKERRKNFVMSIHKRSVRGKQKMSLRDKQKVLRAHITKQKKKGY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ** *: ****:**** :* :** ** *: * ::* : . ...* ::* *::*: *: :**..:.:** . * :: : ..* :****::: . .:: :* *: . . * **. : *:::: :*. *:: *: *:* * . :.:* :.: . : .: **:::.**:*::**:::: . .: : .*::::.: ***. *.: ::: : :**:: : . *. : : : :.:* :**: :***.***:::**.::* *:*: . : : :* *: ::::***:* *.*:::.:*.:. ::* *:**:**::: .**:.*.*** ::*: :: .:*::*::: :.:* : *:*: :*: *.**:: * *****. ** * *.* *:*: ** *:* * :* :* **: .:. : : :* : : : * * * : . .: : : * * :::: *.* . . .*::: : .. : : :: :*::* ** ::. . : : :: * *::. : * : :* ** .. *: .*..* : : : *.:*:**.: *** * : ..* * *:::** .** : :::* ", "identical_positions": 168, "similar_positions": 254, "identity": "21.08%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021217-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NX70-1", "uniprot_id": "MED29_HUMAN", "id": "Q9NX70-1", "name": "Mediator of RNA polymerase II transcription subunit 29", "aln": "---MAASQQQASAASSAAGVSGPSSAGGPGPQQQPQPPAQLVGPAQSGLLQQQQQDFDPVQRYKMLIPQLKESLQTLMKVAAQNLIQNTNIDNGQKSS----DGPIQRFDKCLEEFYALCDQLELCLRLAHECLSQSCDSAKHSPTLVPTATKPDAVQPDS--LPYPQYLAVIKAQISCAKDIHTALLDCANKVTGKTPAPPAGPGGTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DB91-1", "uniprot_id": "MED29_MOUSE", "id": "Q9DB91-1", "name": "Mediator of RNA polymerase II transcription subunit 29", "aln": "---MAAPQPQAAAVSSASGVSGPGSAGGPGPQQQPQP-TQLVGSAQSGLLQQQQQDFDPVQRYKMLIPQLKESLQTLMKVAAQNLIQNTNIDNGQKSS----DAPLQRFDKCLEEFYALCDQLELCLRLAHECLSQSCDSAKHSPTLVPTATKPDAVQPDS--LPYPQYLAVIKAQITCAKDIHTALLDCANKVTGKTTAPSTGPGGSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8JHI6-1", "uniprot_id": "MED29_DANRE", "id": "Q8JHI6-1", "name": "Mediator of RNA polymerase II transcription subunit 29", "aln": "----MASQQMSTNNAQMS-------AQQAAVLQQTQA-QQLS----------QQQDFDPVHRFKMLIPPLKDSLQNVMTIASLNFAHNTAIDNGLKTTEKGNDAAVQRFDKSLEEFYALCDQLELCLRLAHECLSQSIDSTKHSPNLVPTATKPDTVQTES--LSYSQYLSMIKSQISCAKDIHNALLECSKKIAGK------GQGACN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KBL8-1", "uniprot_id": "MED29_DROME", "id": "Q7KBL8-1", "name": "Mediator of RNA polymerase II transcription subunit 29", "aln": "MNPNMNMMPMSGPQMMQVMQSSPSGPPGPVQHQQQQPPQPLQQ-------QQQAEKLDNISRVKSLLGPLRESMFLTIRSSAFALQQNNLADNLKRDTG---AHHVPRFDKHLEDFYACCDQIEIHLKTAMQCLQQQNSSNHYLPGPVTPMRMETFMPDNAGPISYPTYLNTVRVHIQSAKDIHDTLISAAQNISQAD-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . ** *. * * :.:* : * * *: *::*: : :: : :*. ** : : : **** **:*** ***:*: *: * :**.*. .* :: * *.. : :: :.*. ** :: :* .***** :*:..::::: ", "identical_positions": 45, "similar_positions": 52, "identity": "21.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021217-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M9G7-1", "uniprot_id": "UTP25_RAT", "id": "Q5M9G7-1", "name": "U3 small nucleolar RNA-associated protein 25 homolog", "aln": "MGKRRSRGRSQLLSTMTKKQKKHLRDFGEEHPFYDRVSKKEVKPQICQLSESSDS-----SHSESESESEQEHVSG-YHRLLATLKNISEEEEEEEEEEEEEEEDKEE-----VDDSAVGDSEMNGEDGGED------VRVEETAESSETQDHMSLADNSKGK-DGEEPPGVSQKSSEEFTDVKHESLFSLETNFLEEESGGSYSQRTSQDPFQHHINKELQEKEIQAAASSPAATQQLKWPVLGHLVFSSKFQKMETFKPPKDIDLKSLHLQKPLESTWAKTNSQFLSGPGPQKSSSCFTPLQKELFLIMNSYRDLFYPERTALKNGEEVRHVYCLHAINHVLKANAQVLANNSRR-------RTQKLGVGDDDDFRDQGLTRPKVLIVVPFREAALRVVQLFISLLEG---DSKKKIIVSNKKRFQGEYGSDPEERPPNLKRPEDYEAVFVGNIDDHFRIGVAILQRSIRLYAPFYSSDILIASPLGLRTIIGGEGEKKRDFDFLSSIELLIIDQADIYLMQNWEHVLHLMNHMNLLPLDSHGVNFSRVRMWSLNNWSKYYRQTLLFGALQDAQINSVFNKHCVNAQGQVAVRNVP--MTGSISHVLVQLPHVFQRMEAQD--LASVIDARFHFFINKILPQYRDAV--MSHTLIYVPSYFDFVRLRNYFKKEE-LNFTHICEYTQRSGVSRARHFFLQGEKQFLLLTERFHFYKRYTIKGIRNLIFYELPTYAHFYSEVCNMLRATSR----GEEATWTCTVLYSKYDAQRLAAVVGVERAAQMLQSPKSVHLFITGEK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BTT6-1", "uniprot_id": "UTP25_MOUSE", "id": "Q8BTT6-1", "name": "U3 small nucleolar RNA-associated protein 25 homolog", "aln": "MGKRRNRGRSQMLSTMTKKQKKHLRDFGEEHPFYDRVSKKEAKPQICQLPESSDS-----SHSESESESEQEHVSG-YHRLLATLKNVSEEEEEEEEEEEEEEEEEEEEEEEEEDDSAVGDAEMNEEAGSEDGSVGEAAVSEAAEEAAETQEHMSLADNSKEK-DGEEPPGVSQKSSEEFTDVKHESLFSLETNFLEEDSGGSCSQRPSQDPFQQHVNKELKEKEIQAAASSPPATQQLKWPVLGHLVFSSKFQKTETFKPPKDIDLKLLHLQKPLESTWAKTNSQFLSGP--QKSNSSFTPLQKELFLIMNSYRDLFYPERTALKNGEEVRHVYCLHAINHVLKANAQVLANNSRR-------RSQKLGVGEDDDFRDQGLTRPKVLIVVPFREAALRVVQLFISLLEG---DSKKKIIVSNKKRFQGEYGSDPEERPPNLKRPEDYEAVFVGNIDDHFRIGVAILQRSIRLYAPFYSSDILIASPLGLRTIIGGEGEKKRDFDFLSSVELLIIDQADIYLMQNWEHVLHLMNHMNLLPLDSHGVDFSRVRMWSLNNWSKYYRQTLLFGALQDAQINSVFNKHCINAQGQVAVRNVP--MTGSISHVLVQLPHVFQRMEAQD--LSSVIDARFHFFINKILPQYRDAV--MSHTLIYVPSYFDFVRLRNYFKKEE-LNFTHICEYTQKSGISRARHFFLQGEKQFLLLTERFHFYKRYTIKGIRNLIFYELPTYPHFYSEVCNMLRATSR----GEEATWTCTVLYSKYDAQRLAAVVGVERAAQMLQSPKNVHLFVTGEK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68CQ4-1", "uniprot_id": "UTP25_HUMAN", "id": "Q68CQ4-1", "name": "U3 small nucleolar RNA-associated protein 25 homolog", "aln": "MGKRGSRSQSQLLNTLTKKQKKHLRDFGEEHPFYDRVSRKEAKPQICQLSESSDS-----SDSESDSESEPQQVSG-YHRLLATLKNVSEEEEEDEEEEEEE-------------DSIVDDAEMNDEDGGSD----VSVEEEMAAESTESPENVALSADPEGKEDGEEPPGTSQTSPEEFTDAKHESLFSLETNFLEEESGDNSSLKASQDPFLQHVNKELKEKAIQAVATNPKTTHELKWPILGQLFFSSKFQKLETFKPPKDIDLKSLHLQKPLESTWTKTNSQFLSGP--QKSSSPFTPLQKELFLIMNSYRDLFYPERTALKNGEEIRHVYCLHVINHILKANAQVLGNNSRR-------RSQKFGVGDDDDFRDQGLTRPKVLIVVPFREAALRVVQLFISLLEG---DSKKKIIVSNKKRFQGEYGSDPEERPPNLKRPEDYEAVFVGNIDDHFRIGVAILQRSIRLYAPFYSSDILIASPLGLRTIIGGEGEKKRDFDFLSSIELLIIDQADIYLMQNWEHVLHLMNHMNLLPLDSHGVDFSRVRMWSLNNWSKYYRQTLLFGALQDAQINSVFNKYCVNMQGQVAVRNVP--MTGSISHVLVQLPHVFQRMEAEN--LASVIDARFNFFVNKILPQYRDAV--MSHTLIYIPSYFDFVRLRNYFKKEE-LNFTHICEYTQKSGVSRARHFFLQGEKQFLLFTERFHFYKRYTIKGIRNLIFYELPTYPHFYSEICNMLRATNR----GEEATWTCTVLYSKYDAQRLAAVVGVERAAQMLQSNKNVHLFITGEK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PEH4-1", "uniprot_id": "UTP25_DANRE", "id": "Q6PEH4-1", "name": "U3 small nucleolar RNA-associated protein 25 homolog", "aln": "MGKRR-RGK-QEIDNLTKKQKKHLKEFGEQHPFHDKVVERPEKTQILRLPDSPQR-----PEPDSEDDSDAEQPSA-YQKLLSTMIQGDEDDVESEDEESEEEDNEEE-------AEVEGDSEEEVEDTDEE----DGNDAEEVLEDKVEETSDKLQKKHPEKTNGDVEENEEAEMEGEFTDKKNEAAFCLETNMPAEGEENTAQQEQDEDMFVKHQEIELSEEEVGRISQGSKVKTQVKWAKLGVLQCMCPLERFPAIGQASSAPLPPIH--KTLEANWHLLNLPFGAAT-------DVTELQKEMLGLMGTYRDLYLANLSPLKEAKEVRSAYCLHALNHVLKANSRVLRNNAKL-------KESKNG---DEDFRDQGLTRPKVLILVPFRDGALRVVQTFMTLLEP---KGKK-TDASNKKRFKEEYGEETDEKPPNLQRPDDYHAVFSGNIDDHFRIGMSILRHSMRLYAPFYSSDIIIASPLGLRTVLGAEGEKKRDHDFLSSIELLIVDQADVFLMQNWEHLLHVLEHLNLQPLDSHGVDFSRVRMWNLNNWAAYYRQTLVFSAIQEPQITNILTKHCHNYRGQVCSKTIP--KIGSICQVLVQLPHVFQMFHSDS--FMD-QDARFQFFVDKILPQYRDSV--MSHTFIYVPSYFDFVRLRNYLKKED-VSFANISEYSQRSEVSRARHYFQKGEKQFLLFSERFHFYKRYTIKGIHNLIFYGLPTYPHFYSEVCNMLQAGVRE--GGASVSFTCTALYSRYDVHRLAAITGADRAAQMLQSKKTTHLFITGEEKST", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1G1-1", "uniprot_id": "Q9W1G1_DROME", "id": "Q9W1G1-1", "name": "Digestive organ expansion factor homolog", "aln": "MKQKHSKNRAKPYKKPTPARRNER--FSKNYSFIQRSKQMEESHRRERMPTAPKQEYEPVAELLPEIQDDVDETEF-YKKLITGVNNIPTSDILRSKAEKEE-----------------------------------------------DHVIPVPRKIKPKKEKRSEQLGVDLEIYNSFS------------------------KRFDFELSTDNINDLIARKDVKTIKRNWSALGNVRFDIPRLTEDFKEPDCSEPKDIASTEDLQKLEVKASICANAKLP----------------LTALQSQLFYIANNYQDIYYPHRTHG-NAEDIRYVYCLHALNHMLKVRSLILRNNEKVSALAKSQKMSPNEISIPESFRDQGLKRMKVVFVVPFRESALRIVNILGDLLFGSQDDQARKTSIANYERFLGDYSGNTIYFPKTNPKPMDYEQTFSGNTDDNFKLGIRFTKKTMSLFSDMNASDMLIASPLGLRMLVT---DKESDFDFLNSIELLIIDQAELFLAQNWENLLHSLDHLHLQPQKLPDTNCQRVRTWCLSGASSFYRQTLFFSSHELPEFRAVFNSKCNNYQGKVRDSNLV--EHGDIRNVLTPIHQVFRLINCSS--VETTFDDRFQYFVKNIMPQFSKPG--FSHCMLYVPSYFDYVRIRNHFKTEM-VSFVQINEYTKKEKISRARDIFFHSGASVLLYSERAHFFRRTRIKGIRNLIMYQPPNFPHFYSEIINLMLKTNQNPRDGFGDEMSVSILYTKYDLLSLSNIVGSENAAKLTSGQKDSYLFSTKT----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40498-1", "uniprot_id": "UTP25_YEAST", "id": "P40498-1", "name": "U3 small nucleolar RNA-associated protein 25", "aln": "MSDSSVREKNDNFRGYRKRGRQELRKIKRSSARTEGGSTETLEDVAEDIDHRSDED--EVSDVDSGDDFDIEDEEGKKEKVYDALLTILKSEHPEPKRRRRE----------------------------------------------ADESNKAPAEVGEDEHENTEHGPVDDQLEIENGLLGNHEDDNDDDSSGDEKDIDSEDEQDPFESHFNQVPEKFVDKLSNAFKTKSVKYKSVKGSLSDSESYIYAKPVVIGEEALVESPYRSSSIYSYFLKQRLKVQNGLLDKK-----TDPLTALQKKLVDPMFQYKDILYEYDSYEKDEDEYRDLYALHVLNHIYKTRDRILKNNQRLQ------------DNPDTEHLDQGFTRPKVLIVVPTREVAYRVVDKIIS--------KSGIDQVDKKGKFYDQFRDDS---LPPKSKPKSFQHIFRGNTNDFFVVGLKFTRKAIKLYSNFYQSDIIVCSPLGIQMILENTDKKKRQDDFLSSIELMVIDQLHSIEYQNISHIFTIFDHLNKIPDQQHEADFSRIRMWYINEQAKLFRQTMVFTKYISPAANSLINGRCRNMAGRWKNHKVIGSENSSIGQSGLKIRQIFQRFDIIGNSIIEEPDYRFKFFTSVIIPGIVKSTGYEDGILIYIPDYTDFIRIRNYMKEKTTILFGDINEYSSQRQLNANRSLFQQGRLKVMLYTERLHHYRRYEIKGVKSVVFYKPPNNPEFYNEVVRFIGKNAFLG-NTDLNISTVRCIYSKLDGLSLERIVGTKRAAVLSHAQKEIYEFK-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : : . ::. : .. . : . : .. .. . : : :. . .:: : .: . . .* : . . . . : .: : : .:: : .* **.::. *:*: : : .: * *.**.:**: *.. :* ** : .. ***:.* **:::** *: * *:*: : : :* :: :. :* .:. * ** :* * :*: : :::: *:: : **:::.****:: :: .*: : ***.*:**:::** . ** .::: ::*:: * . .: .*:* * :. : :***:.* . ::. * * *: .: ..* : : ::*: :. . . * **::* . *:* .. . ::*:*.* *::*:**::* : : * .* **:.: :. * * :. ..:* :** *.::* ***::.:::* *. ..**.*: .:: : :*:: * * :.* ..** : . * : * ", "identical_positions": 110, "similar_positions": 210, "identity": "13.66%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021217-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RDU9-1", "uniprot_id": "M0RDU9_RAT", "id": "M0RDU9-1", "name": "", "aln": "MFNLMANCCNLFKRWREPVRKVTLVMVGLDNAGKTATAKGIQGEHPEDVAPTVGFSKIDLRQGKFEVTIFDLGGGKRIRGIWKNYYAESYGVIFVVDSSDEDRMEETKETMSEVLRHPRISGKPILVLANKQDKEGALGEADVIECLSLEKLVNEHKCLCQIEPCSAVLGYGKKIDKSIKKGLYWLLHIIAKDFDALSERIQKDTTEQRALEEQEKCERAERVRKLREERSFPPPPTNREQEQTELDGTSGLAEMDSGPVLTNPFQPIAAVIIENEKKQEKEKKKKTAEKDSDVGHPEHKGEQEGAESQNEAGGCLR-NPHRDVVNSYKEALSQQLDNEDELDQRVSEPGDNSKKKTKKLRMKRSHRVEPVNTDESAPKSPTPPPPPPPVGWGTPKVTRLPKLEPLGETRHNDFYGKPLPPLAVRQRPNGDAQDMIS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q640N2-1", "uniprot_id": "AR13B_MOUSE", "id": "Q640N2-1", "name": "ADP-ribosylation factor-like protein 13B", "aln": "MFSLMANCCNLFKRWREPVRKVTLVMVGLDNAGKTATAKGIQGEHPEDVAPTVGFSKIDLRQGKFQVTIFDLGGGKRIRGIWKNYYAESYGVIFVVDSSDEERMEETKETMSEVLRHPRISGKPILVLANKQDKEGALGEADVIECLSLEKLVNEHKCLCQIEPCSAVLGYGKKIDKSIKKGLYWLLHIIAKDFDALSERIQKDTTEQRALEEQEKRERAERVRKLREER---------EREQTELDGTSGLAEIDSGPVLANPFQPIAAVIIENEKKQEKEKKKQTVEKDSDVGLLEHKVEPEQAAPQSEADCCLQ-NPDERVVDSYREALSQQLDSEDEQDQRGSESGENSKKKTKKLRMKRSHRVEPVNTDESTPKSPTPPQPPPPVGWGTPKVTRLPKLEPLGETRHNDFYGKPLPPLAVRQRPNGDAQDTIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3SXY8-1", "uniprot_id": "AR13B_HUMAN", "id": "Q3SXY8-1", "name": "ADP-ribosylation factor-like protein 13B", "aln": "MFSLMASCCGWFKRWREPVRKVTLLMVGLDNAGKTATAKGIQGEYPEDVAPTVGFSKINLRQGKFEVTIFDLGGGIRIRGIWKNYYAESYGVIFVVDSSDEERMEETKEAMSEMLRHPRISGKPILVLANKQDKEGALGEADVIECLSLEKLVNEHKCLCQIEPCSAISGYGKKIDKSIKKGLYWLLHVIARDFDALNERIQKETTEQRALEEQEKQERAERVRKLREER------KQNEQEQAELDGTSGLAELD--PEPTNPFQPIASVIIENEGKLEREKKNQKMEKDSDGCHLKHKMEHEQIETQGQVNHNGQKNNEFGLVENYKEALTQQLKNEDETD-RPSLESANGKKKTKKLRMKRNHRVEPLNIDDCAPESPTPPPPPPPVGWGTPKVTRLPKLEPLGETHHNDFYRKPLPPLAVPQRPNSDAHDVIS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JHI3-1", "uniprot_id": "AR13B_DANRE", "id": "Q8JHI3-1", "name": "ADP-ribosylation factor-like protein 13B", "aln": "MFNLMANCCNWLKRWREPARKVTLVMVGLDNAGKTATVRGIQGESPLDVAPTVGFSKVDLKQGKFEVTIFDLGGGKRIRGIWKNYYSESYGVVFVVDSSDVQRIQETRDTMAEVLRHPRIAGKPVLVLANKQDQDGAMAEADIIETLSLEKLVNENKCLCQIEPCSAVLGYGKKVDKSIKNGLNWLLNNIAKDYEAISERVQKDTAEQKAQEEQDKKERAERVRRIREER------DRQEREEAEREGRTLKEEELDDVNMFNPFQPINNVLTENQDRLNREKEMQRQRENG-----QQGSVQEQIALQDEEE------------EEEDEESERQTPESTESG-----AVDQTKKKTRKLRLKRKHRVDPLRMEEAAPKSPTP--PPLPVGWATPKVSRLPKLEPLGDTRHSDFYGKPLPPVAIRQRPNSDTHDVIS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.***.**. :******.*****:************.:***** * **********::*:****:********* **********:*****:******* :*::**:::*:*:******:***:********::**:.***:** *********:***********: *****:*****:** ***: **:*::*:.**:**:*:**:* ***:* *******::**** *:*::* :* : * ****** *: **: : ::**: : .::. :: * *.: :. * :* .. * . : ****:***:**.***:*:. ::.:*:**** ** ****.****:*********:*:*.*** *****:*: ****.*::* **", "identical_positions": 250, "similar_positions": 94, "identity": "57.21%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021219-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q499E6-1", "uniprot_id": "AIRIM_MOUSE", "id": "Q499E6-1", "name": "AFG2-interacting ribosome maturation factor", "aln": "MAHDQPLLVVQEALRKCFPVVEEQQNLWQSTLQDCSPLLSSLSNLAEQLQAAQSLRFEDVPALRPFPDLQERLRRKQLEAGDVVLDKLAERLATLLKVRNTINSHVEQVFQAYEQHAAVLDIDTVLRPSVVSPSVADMLEWLQDIDRHYGSSYLKRKYLLSSIHWGDLASIQALPKAWDQISENECQTLVSDVLVSVSFFLEEPGGCAASGDLEHHS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AB92-1", "uniprot_id": "D4AB92_RAT", "id": "D4AB92-1", "name": "", "aln": "MAHDQPLLVVQEALKKCFPVVEEQQDLWQSTLQDCLPLLSSLSNLAEQLQAAQSLRFEDVLALRPFPDLQERLRRKQLEAGDIVLDKLTERLATLLRVRNTISSHVEQVFQTYEQHADVLDIDTLLRPSVVSPSVTDMLEWLQDIDRHFRSSYLKRKHLLSSIHWGDLASIQALPKAWDQISEDECQTLVSDILLSVSFFLEEAGSRAVSGDLEHRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NX04-1", "uniprot_id": "AIRIM_HUMAN", "id": "Q9NX04-1", "name": "AFG2-interacting ribosome maturation factor", "aln": "MTQDRPLLAVQEALKKCFPVVEEQQGLWQSALRDCQPLLSSLSNLAEQLQAAQNLRFEDVPALRAFPDLKERLRRKQLVAGDIVLDKLGERLAILLKVRDMVSSHVERVFQIYEQHADTVGIDAVLQPSAVSPSVADMLEWLQDIERHYRKSYLKRKYLLSSIQWGDLANIQALPKAWDRISKDEHQDLVQDILLNVSFFLEE--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JHH5-1", "uniprot_id": "AIRIM_DANRE", "id": "Q8JHH5-1", "name": "AFG2-interacting ribosome maturation factor", "aln": "MP-GSALLSLQQELRRGFEALKAAKDTFDGGHAECQELVSSLGNLAPQLKALKQVQISETP-LSGFPCLQQRLHYKLSLAVDALLAKLAEKMAALQKVWDAFAQQVFTVVQLYEKNTDALDISVCVSRSAVCPSVSDMLEWLQDADRYYRLQLMQSRLLLQTLTPTDLTSMETAPNRWRSVRSARQEERIADALCQVSIFLETE-------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . .** :*: *:: * .:: :. ::. :* *:***.*** **:* :.:::.:. * ** *::**: * * * :* ** *::* * :* : . .:* *.* **::: .:.*.. : *.*.***:******** :*:: . :: : **.:: **:.::: *: * : . . : : * * .**:*** ", "identical_positions": 66, "similar_positions": 74, "identity": "30.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021219-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UI12-1", "uniprot_id": "VATH_HUMAN", "id": "Q9UI12-1", "name": "V-type proton ATPase subunit H", "aln": "-MTKMDIRG-AVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISAEDCEFIQRFEMKRSPEEKQEMLQTEG---------SQCAKTFINLMTHICKEQTVQYILTMVDDMLQENHQRVSIFFDYARCSKNTAWPYFLPMLNRQDPFTVHMAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQKLRGSGVAVETGTVSSSDSSQYVQCVAG-CLQLMLRVNEYRFAWVEADGVNCIMGVLSNKCGFQLQYQMIFSIWLLAFSPQMCEHLRR--YNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALAMIQCKVLKQLENLEQQKYDDEDISEDIKFLLEKLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTKLLEVSD---------DPQVLAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNWEYLGKQLQSEQPQTAAARS---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BVE3-1", "uniprot_id": "VATH_MOUSE", "id": "Q8BVE3-1", "name": "V-type proton ATPase subunit H", "aln": "-MTKMDIRG-AVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISAEDCEFIQRFEMKRSSEDKQEMLQTEG---------SQCAKTFINLMTHISKEQTVQYILTMVDDMLQENHQRVSIFFDYAKRSKSTAWPYFLPMLNRQDPFTVHMAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQKLRGSGVAVETGTISSSDSSQYVQCVAG-CLQLMLRVNEYRFAWVEADGVNCIMGVLSNKCGFQLQYQMIFSIWLLAFSPQMCEHLRR--YNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALAMIQCKVLKQLENLEQQKYDDEDISEDIKFLLEKLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTKLLEVSD---------DPQVLAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNWEYLGKQLQSEQPQTAAARS---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZWI2-1", "uniprot_id": "A0A8I5ZWI2_RAT", "id": "A0A8I5ZWI2-1", "name": "V-type proton ATPase subunit H", "aln": "-MTKMDIRG-AVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISAEDCEFIQRFEMKRCSEEKQEMLQTEG---------SQCAKTFINLMTHISKEQTVQYILTMVDDMLQENHQRVSIFFDYAKRSKSTAWPYFLPMLNRQDPFTVHMAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQKLRGSGVAVETGTISASDSSQYVQCVAG-CLQLMLRVNEYRFAWVEADGVNCIMGVLSNKCGFQLQYQMIFSIWLLAFSPQMCEHLRR--YNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALAMIQCKVLKQLENLEQQKYDDEDISEDIKFLLEKLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTKLLEVSD---------DPQVLAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNW-YVSIQASQNRPNTSYAEVTVVRSQLCS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B0R0V8-1", "uniprot_id": "B0R0V8_DANRE", "id": "B0R0V8-1", "name": "V-type proton ATPase subunit H", "aln": "----MDIRG-AVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISGEDCEFIKKFEVAG-SEDKQAILTNEG---------HQCAKTFLNLMAHISKEQTVQYILTLIDDTLQENHQRVNIFFDYAKKTKNTAWSYFLPMLNRQDLFTVHMAARIIAKLAAWGRDLMEGSDLNYYFNWIKTQLSSQKLHGTGAEPGTGTISPSESSQYVQCVAG-CLQLMLRVNEYRFAWVEADGVNCITAVLSNKCGFQLQYQMIFCVWLLAFSPQLCEQLRR--YNVVPALSDILQESVKEKVTRIILAAFRNLLEKSAERETRQEYALAMIQCKVLKQLENLDQQKYDDEDITDDIKFLLERLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTRLLEVSD---------DPQVIAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQLVRYNALLAVQKLMVHNWEYLGKQLQSTEQTTPAVAARS-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3J1-1", "uniprot_id": "VATH_DROME", "id": "Q9V3J1-1", "name": "V-type proton ATPase subunit H", "aln": "MTTALYLPEENIDMIAATSVLQQQAADIRTRTINWASYMQSQMISEEDYKAISALDKSR-----ASFLAQNS---------SQVVKTLLNLVSHLSKDSTIQYILVLLDDLLQEDRSRVDLFHDTAGKLKQCIWGPFLNLLNRQDGFIVNMSSRILAKFACWGHETMPKSDLNFYLQFLKDQLAS------------------NNNEYIQSVAR-CLQMMLRVDEYRFAFVGVDGISTLIRILSTRVNFQVQYQLIFCLWVLTFNPLLAAKMNK--FSVIPILADILSDCAKEKVTRIILAVFRNLIEKPEDSSVAKDHCIAMVQCKVLKQLSILEQRRFDDEDITADVEYLSEKLQNSVQDLSSFDEYATEVRSGRLEWSPVHKSAKFWRENAQRLNEKNYELLRILVHLLETSK---------DAIILSVACFDIGEYVRHYPRGKHVLEQLGGKQIVMQHLGHEDPNVRYEALLAVQKLMVHNWEYLGKQLEKENENQKQGAAPIAGKA---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41807-1", "uniprot_id": "VATH_YEAST", "id": "P41807-1", "name": "V-type proton ATPase subunit H", "aln": "-------MG-ATKILMDSTHFNEIRSIIRSRSVAWDALARSEELSEIDASTAKALESILVKKNIGDGLSSSNNAHSGFKVNGKTLIPLIHLLSTSDNEDCKKSVQNLIAELLSSDKYGDDTVKFFQEDPKQLEQLFDVSLKGDFQTVLISGFN-VVSLLVQNGLHNVKLVEKLLKNNNLINILQNIEQMDTCYVCIRLLQELAVIPEYRDVIWLHEKKFMPTLFKILQRATDSQLATRIVATNSNHLGIQLQYHSLLLIWLLTFNPVFANELVQKYLSDFLDLLKLVKITIKEKVSRLCISIILQCCS-TRVKQHKKVIKQLLLLGNALPTVQSLSERKYSDEELRQDISNLKEILENEYQELTSFDEYVAELDSKLLCWSPPHVDNGFWSDNIDEFKKDNYKIFRQLIELLQAKVRNGDVNAKQEKIIIQVALNDITHVVELLPESIDVLDKTGGKADIMELLNHSDSRVKYEALKATQAIIGYTFK---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : : :*:..: * : :.: :* * . . :: * .. : .:::*:: ::. : : :: : *..:: . . *. : : . : . : ::: :. * . : : : : * . :* : : ::* : : . : . : *.: .:*:**: :: :*:*:*.* :. .: : . . * .::. ****:*: :: : : . . . : :: :.* :. *.::::.**:: *:. * * * :. *:*:***** :*: * * *** * . ** :* .:::.**:::: * .**:.. : :: ** *: . *. *.. *::: *** :*: : *.* *:*:** *.* :: :.: ", "identical_positions": 74, "similar_positions": 164, "identity": "14.37%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021220-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A218-1", "uniprot_id": "DMRT3_RAT", "id": "D4A218-1", "name": "Doublesex and mab-3 related transcription factor 3", "aln": "MNGYGSPYLYMGGPVSQPPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAAATAATASQSSPASQASQPPAPPRPATELAAAAALRWVAEPQPGTLPAQIAKPDLTEDRLGDSSSADNAAESFSDKDTDQRSSPDVVKSKNCFTPESPE-IVSVDEGGYAVQKNGGNPESCPDSPKYHAEQSHLLIEGPSGTVSLPFSLKANRPPLEVLKKIFPNQKPTVLELILKGCGGDLVSAVEVLLSSRSSAAGAERT--AEESLVLPSSGHIFEHTLGSYPISSSKWSVGSAFRVPDTLRFSADSSN-VVPNPLAVPLQHPFPQPPRYPLMLRNTLARNQSSPFLPNDVTLWNTMTLQQQYQLRSQYVSPFPSNSTSVFRSSPVLSSRTTEDPRISIPDDGCPIVAKQSIYT-EDDYDERSDSSDSRILNTSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80WT2-1", "uniprot_id": "DMRT3_MOUSE", "id": "Q80WT2-1", "name": "Doublesex- and mab-3-related transcription factor 3", "aln": "MNGYGSPYLYMGGPVSQPPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAAATAATASQSSPASQASQPPAPPRPTAELAAAAALRWVAEPQPGTLPAQLAKPDLTEERVGDSSSTDNTAEAFSDKDTDQRSSPDVVKSKNCFTPESPE-IVSVDEGGYAVQKNGGNPESCPDSPKYHAEQSHLLIEGPSGTVSLPFSLKANRPPLEVLKKIFPNQKPTVLELILKGCGGDLVSAVEVLLSSRSSAAGAERT--AEESLVLPSSGHIFEHTLGSYPISSSKWSVGSAFRVPDTLRFSADSSN-VVPNPLAVPLQHPFPQPPRYPLMLRNTLARNQSSPFLPNDVTLWNTMTLQQQYQLRSQYVSPFPSNSTSVFRSSPVLSSRTTEDPRISIPDDGCPIVTKQSIYT-EDDYDERSDSSDSRILNTSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQL9-1", "uniprot_id": "DMRT3_HUMAN", "id": "Q9NQL9-1", "name": "Doublesex- and mab-3-related transcription factor 3", "aln": "MNGYGSPYLYMGGPVSQPPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAVA----APQPPPASQPSQP-QPPRPAAELAAAAALRWTAEPQPGALQAQLAKPDLTEERLGDGKSADN-TEVFSDKDTDQRSSPDVAKSKGCFTPESPE-IVSVEEGGYAVQKNGGNPESRPDSPKCHAEQNHLLIEGPSGTVSLPFSLKANRPPLEVLKKIFPNQKPTVLELILKGCGGDLVSAVEVLLSSRSSVTGAERTSAEPESLALPSNGHIFEHTLSSYPISSSKWSVGSAFRVPDTLRFSADSSN-VVPSPLAGPLQPPFPQPPRYPLMLRNTLARSQSSPFLPNDVTLWNTMTLQQQYQLRSQYVSPFPSNSTSVFRSSPVLPARATEDPRISIPDDGCPFVSKQSIYT-EDDYDERSDSSDSRTLNTSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P83758-1", "uniprot_id": "DMT3A_DANRE", "id": "P83758-1", "name": "Doublesex- and mab-3-related transcription factor 3a", "aln": "MNGYGSPYLYMGGPVSQP-RAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRRQQANESLESLIPESLRALPG-----------------ITVSSGEQS-ANPR-----ASDIDLRWNTETG-----TPKTPQDLSDELSGEQSGGEN---GGSDREPEAVSSPEESKPNLCCTPDTSDPSPQLEESRFGLSKSCSDPEPKSDNPKYSPEP-NLLIEGLSGSVSLPFSLRANRPPLEVLKKIFPAHKPAVLELILKGCGGDLVGAIEILLSSRSTMKPEKILSESSDALVLPSNGHLFEHPLSSYPVSSSKWSVGSAFRVPDSLRFSSESSGGVVPGPLSMPLQHGFPQPPRYPLMLRNSLSRGQAGPFMHNDVTLWNTMTLQQQYQLRSQYVPPFSGPSAGVIRSSPLLTSRPSEEHRISIQEESCPVIAKQSMYAADEEYDDRSDSSDSRILNTSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************** *********************************************************************:******* ..*. .*. ** *: *** :*. : : **::: *: .. :* **::.: ***: *.: * **::.: .::*. :.:.*. .:**. .*.** .* :***** **:*******:************** :**:**************.*:*:******: : ::*.***.**:***.*.***:***************:****::**. ***.**: *** *************:*:*.*:.**: **********************.**.. *:.*:****:*.:*.:*: **** ::.**.::***:*: :::**:******** *****", "identical_positions": 294, "similar_positions": 98, "identity": "61.12%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021220-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NQL9-1", "uniprot_id": "DMRT3_HUMAN", "id": "Q9NQL9-1", "name": "Doublesex- and mab-3-related transcription factor 3", "aln": "MNGYGSPYLYMGGPVSQPPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQPQPPRPAAELAAAAALRWTAEPQPGALQAQLAKPDLTEERLGDGKSADNTEVFSDKDTDQRSSPDVAKSKGCFTPESPEIVSVEEGGYAVQKNGGNPESRPDSPKCHAEQNHLLIEGPSGTVSLPFSLKANRPPLEVLKKIFPNQKPTVLELILKGCGGDLVSAVEVLLSSRSSVTGAERTSAEPESLALPSNGHIFEHTLSSYPISSSKWSVGSAFRVPDTLRFSADSSNVVPSPLAGPLQPPFPQPPRYPLMLRNTLARSQSSPFLPNDVTLWNTMTLQQQYQLRSQYVSPFPSNSTSVFRSSPVLPARATEDPRISIPDDGCPFVSKQSIYTEDDYDERSDSSDSRTLNTSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DFI0-1", "uniprot_id": "DMT3B_DANRE", "id": "Q9DFI0-1", "name": "Doublesex- and mab-3-related transcription factor 3b", "aln": "------------------------------------MLSWLKGHKRYCRFKDCTCEKCILIIERQRV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :****************************** ", "identical_positions": 30, "similar_positions": 1, "identity": "6.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021220-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADS6-1", "uniprot_id": "D4ADS6_RAT", "id": "D4ADS6-1", "name": "Integrator complex subunit 7", "aln": "--MASNSTKSFLADAGYGEQELDANSALMELDKGLRSGKLGEQCEAVVRFPRLFQKYPFPILINSAFLKLADVFRVGNNFLRLCVLKVTQQSEKHLEKILNVDEFVKRVFSVIHSNDPVARAITLRMLGSLASIIPERKNAHHSIRQSLDSHDNVEVEAAVFAAANFSAQSKDFAVGICNKISEMIQGLATPVDLKLKLIPILQHMHHDAILASSARQLLQQLVTSYPSTKMVIVSLHTFTLLAASSLVDTPKQIQLLLQYLKSDPRKAVKRLAVQDLKLLASKTPHTWSKENIQALCECALHTPYDSLKLGMLSVLSTLSGTIAIKHYFSVAPGNVGSSPRSSDLVKLAQECCYHSNRAIAAHGVRVLTNITVSCQEKDLLSLEQDAVFGLESLLVLCSQDDSPGAQSTVKSALSCMVKLAKGRPHLSRSVVDTLLTQLHSS---QDAARILMCHCLAAIAMKLPVLG--------------------------DGMLG----DLVELYKVIGRSATDKQQELLVSLATVIFVASQKALSAEVKAVIKQQLESVSSGWTVYRIARQASRMGNHDMARELYQSLLTQVASEHFYFWLNSLKEFSHAEQCLTG--------------LQEGSFSSALSCIAESLKFYHKGIASLTAASTPLNPLSFQCEFVKLRIDLLQAFSQLICTCNSLKTSPPPAIATTIAMTLGNDLQRCGRISNQMKQSMEEFRSLASRYRDLYQASFDADSATLRNVELQQQSCLLIAHAIEALVLDPESASFQEYGSTGAAHADSEYERRMMSVYSHVLEEVESLNRKYAPVSYMHTACLCNAIIALLKVPLSFQRYFFQKLQSTSIKLALSPSPRNPAEPIAVQNNQQLALKVEGVVQHGSKPG-LFRRIQSVCLNVSSTLQS---KSSQDYKIPVDSMTNEMEQRVEPHNDYFSTQFLLNFAVLGTHSITVESSVRDANGIVWKTGPRTTMFVKSLEDPYSQQIRLQQQQAQQPLQPQPQPQPQPRGAYTRF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TQK1-1", "uniprot_id": "INT7_MOUSE", "id": "Q7TQK1-1", "name": "Integrator complex subunit 7", "aln": "--MASNSTKSFLADAGYGEQELDANSALMELDKGLRSGKLGEQCEAVVRFPRLFQKYPFPILINSAFLKLADVFRVGNNFLRLCVLKVTQQSEKHLEKILNVDEFVKRVFSVIHSNDPVARAITLRMLGSLASIIPERKNAHHSIRQSLDSHDNVEVEAAVFAAANFSAQSKDFAVGICNKISEMIQGLATPVDLKLKLIPILQHMHHDALLASSARQLLQQLVTSYPSTKMVIVSLHTFTLLAASSLVDTPKQIQLLLQYLKNDPRKAVKRLAVQDLKLLASKTPHTWSKENIQALCECALHTPYDSLKLGMLSVLSTLSGTIAIKHYFSVVPGNVGSSPRSSDLVKLAQECCYHSNRGIAAHGVRVLTNITVSCQEKDLLSLEQDAVFGLESLLVLCSQDDSPGAQSTVKSALSCMVKLAKGRPHLSRSVVDTLLTQLHSS---QDAARILMCHCLAAIAMQLPVLG--------------------------DGMLG----DLVELYKVIGRSATDKQQELLVSLATVIFVASQKALSAEVKAVIKQQLESVSSGWTVYRIARQASRMGNHDMARELYQSLLTQVASEHFYFWLNSLKEFSHAEQCLTG--------------LQEDSFSSALSCIAESLKFYHKGIASLTAASTPLNPLSFQCEFVKLRIDLLQAFSQLICTCNSLKTSPPPAIATTIAMTLGNDLQRCGRISNQMKQSMEEFRSLASRYRDLYQASFDADSATLRNVELQQQSCLLIAHAIEALVLDPESASFQEYGSTGAAHADSEYERRMMSVYSRVLEEVESLNRKYAPVSYMHTACLCNAIIALLKVPLSFQRYFFQKLQSTSIKLALSPSPRSPAEPIAVQNNQQLALKVEGVVQHGSKPG-LFRRVQSVCLNVSSTLQS---KSGQDYKIPIDSMTNEMEQRVEPHNDYFSTQFLLNFAVLGTHSITVESSVRDANGIVWKTGPRTTMFVKSLEDPYSQQIRLQQQ-AQQPLQPQPLPQPQPRSAYTRF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NVH2-1", "uniprot_id": "INT7_HUMAN", "id": "Q9NVH2-1", "name": "Integrator complex subunit 7", "aln": "--MASNSTKSFLADAGYGEQELDANSALMELDKGLRSGKLGEQCEAVVRFPRLFQKYPFPILINSAFLKLADVFRVGNNFLRLCVLKVTQQSEKHLEKILNVDEFVKRIFSVIHSNDPVARAITLRMLGSLASIIPERKNAHHSIRQSLDSHDNVEVEAAVFAAANFSAQSKDFAVGICNKISEMIQGLATPVDLKLKLIPILQHMHHDAILASSARQLLQQLVTSYPSTKMVIVSLHTFTLLAASSLVDTPKQIQLLLQYLKNDPRKAVKRLAIQDLKLLANKTPHTWSRENIQALCECALQTPYDSLKLGMLSVLSTLSGTIAIKHYFSIVPGNVSSSPRSSDLVKLAQECCYHNNRGIAAHGVRVLTNITVSCQEKDLLALEQDAVFGLESLLVLCSQDDSPGAQATLKIALNCMVKLAKGRPHLSQSVVETLLTQLHSA---QDAARILMCHCLAAIAMQLPVLG--------------------------DGMLG----DLMELYKVIGRSATDKQQELLVSLATVIFVASQKALSVESKAVIKQQLESVSNGWTVYRIARQASRMGNHDMAKELYQSLLTQVASEHFYFWLNSLKEFSHAEQCLTG--------------LQEENYSSALSCIAESLKFYHKGIASLTAASTPLNPLSFQCEFVKLRIDLLQAFSQLICTCNSLKTSPPPAIATTIAMTLGNDLQRCGRISNQMKQSMEEFRSLASRYGDLYQASFDADSATLRNVELQQQSCLLISHAIEALILDPESASFQEYGSTGTAHADSEYERRMMSVYNHVLEEVESLNRKYTPVSYMHTACLCNAIIALLKVPLSFQRYFFQKLQSTSIKLALSPSPRNPAEPIAVQNNQQLALKVEGVVQHGSKPG-LFRKIQSVCLNVSSTLQS---KSGQDYKIPIDNMTNEMEQRVEPHNDYFSTQFLLNFAILGTHNITVESSVKDANGIVWKTGPRTTIFVKSLEDPYSQQIRLQQQQAQQPLQQQ-----QQRNAYTRF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JGR7-1", "uniprot_id": "INT7_DANRE", "id": "Q8JGR7-1", "name": "Integrator complex subunit 7", "aln": "--MSLSAARSFLSEAAYGEQELDANSALMELDKGLRSCKLGEQCEAVVLFPKLFQKYPFPILINSAFLKLADIFRLGNNFLRLCVLKVTQLSEKHLEKILNVDEFVKRVFSVIHSNDPVARAITLRMLGSLASIIPERKNAHHSIRQSLDSHDNVEVEAAIFAAASFSSHSKDFAAGICNKISEMIQGLDTPVELKLKLIPMLQHMHHDASLASCSRELLQELVSSYPSTSMLIVTLHTFTQLATSSLVDIPEQICLLLQYLKEDPRKAVKRLSIQDLKLLAKKAPHLWTRKNIQVLCECALHTPYNSLKLGMLSVLSTLSGTIAIKQYFSPNAGDSSPAPHHTDLVKLAQECCYHSDLAVAAHGITVLTSIAAFCPEKEVIQLEQETVMGMESLILLCSQDDSKTAQATLKTALTSLVQMLKTCPHLSQSSVELLLRQLHCA---CDPARVLMCQALAAIATQQPVLV--------------------------EGMLG----DLLELFRVASHRTSEKQQELLVSLATVLFVASQASLSAEVKAVIRQQLENVANGWTVYQIARQASRMGCHDFSRELYQSLRTRVASEHFYFWLNSLMEFSQAEQCLSG--------------LEDGDYSAAMSAISEALKSYQKGIASLTAASTPLSPLTFQCEFVKLRIDTLQALSQLICTCNSLKTSPPPAIATTIALSSGSDLQRCGRISTQMKFSMDEFRSLAARYADLYQSSFDADYATLRNVELQQQSCLLVSYVIEALIIDPQTASFQEFGTHGSILAESEYELRMMAVFNHVLEEVENLSRKHPPVSYLHTGCLCDTVIAILKIPLSFQRYFFQKLQSTSIKLALSPSPRTPNEPIPVQNNQQLTLKVEGVIQHGSSPG-LFRKIQAVCLKVSSTLQT---KPGSDFKIPLESKTNEIEQKVEPHNDYFSTQFLLNFSILGTHQVSVEASVVDTSGIEWKTGPKNTVSVKSLEDPYSQQLRHQLQQQQQNVPQP----AAQRNISTRFQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VT41-1", "uniprot_id": "INT7_DROME", "id": "Q9VT41-1", "name": "Integrator complex subunit 7", "aln": "MSHLTGTRVSTFNESFLNENEHDSNAVLMELDKGLRSTKQGIQCEAVVRFPRLFEKYPFPILINSSFIKLADYFVSGSNLLRFWVLRVCQQSENHLDKILNIDSFVRCIFVVMHSNDPVARALLLRTLGAVSRVIPEKQQVHHAIRRALDSHDTVEVEAAIYASSCFAAQSSSFAISMCAKISDMIESLQVPVPMKLLLIPVLRHMHHEATTASLVSRLCMDLLPKYPAQSFVVAIIDTLTQLSSRTLVGVPGQLDVLLDFMQDLRTPVRIQVLRSFNELAGRQSVHAWPKPAIKALIDRFELCTNSKEQFLFLSILLKLSECPLTCQQLLREHRVALLRLCIQCISKLDDYTTAT--QAMAVLSVLVAFGLKKKGSGEQVDDILHMVNLHMEGLLLCTAKRSE--CTRDLRRVLTYGIRITKANAEFGTSFIGIVTNSLGDKGAYPPANAELMCEALAGLCEHFQLRKYAFSTAEDLIVDENAMDTDELPPPKINPMLARLPLILHKLNTIIDQENCDQQLRSVEILSSLVLQTTMGCYLPQKVVQCFEKCLGRLNCWTLYRIARTASRYGHHYVAAHIYTKVSQIVISDHMHYFLVALSQISQAECILNYGLEYAYMRDNYAPKVAPEPLIPLMKRLEMASNLYQQALASLRAGSSPQHPCTFQLEYLKIRAQFLQTLHLAVTVKNAQVIVPPPAIAGSLAQNSRDYLQKFGHVTNQLRKLVKALKACEETYARLYKSSFDADHVTLEFLEVAEFQCALFAHIIESICYATPPEPPVFLTTG--DHPETRYFAASCQRMEQMQKNLPQEPANAKTISNRHLDVIIAQIEIITKTPLCLPRYFFQILQSTQIKLSVSPQPRSATEPVNVQSGSNLVIKVEGVLQHFSKQKKHFRRVESVQLSLTSQLITPPPRSSQELPKQGANDTVTLNQIVKPQRDFLSGSFLLPISNGGHFQVTLETFVVDENGITWCTGPKSSMVVRVLEDPSKQGAPAPSTSQAVGQTRRF--------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: * : :: .*:* *:*:.********** * * ****** **:**:**********:*:**** * *.*:**: **:* * **:**:****:*.**: :* *:*********: ** **::: :***:::.**:**::*****.******::*:: *:::*..** .:* ***:**:.* .** :** ***:*:****:* ** .* :*:..**: .:::. :.*:* *:: :**. * *: :**::::. . :: . :* . :: * *.: *:.* : . .. :: :**:* .** : : : ** : .:*. .: * .: ::: : : . : :*.*:: :: .. . :: .*. ::: * ..:. * : : .* . ***..**.:. : : : **. * :* : .: ::* . : *::::: :: . : . :: . . **:*:*** *** * * .: .:* .: * *:*::::* :* ::*:** *. : . :. : : : *::.:*** *.*:* * :** *::*:* : **:: : . *: ****** ::* . . **: *:::.*:: :. ::: * **::***** .**. :*: : .* *.:: **:: . . . : .::.* .:: ::: . : .:* * : : : * **.: ***** ****.***::**.**.. **: **...:*.:*****:** *. **::::* *.::* * : :...: . * ::* *:*:.*::* .*** :: * ..:::*: * * .** * ***:.:: *: **** .* ", "identical_positions": 295, "similar_positions": 321, "identity": "28.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021223-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70596-1", "uniprot_id": "MC4R_RAT", "id": "P70596-1", "name": "Melanocortin receptor 4", "aln": "MNSTHHHGMYTSLHLWNRSSHGLHGNASESLGKGHSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLN-STDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVRRVGIIISCIWAACTVSGVLFIIYSDSSAVIICLITMFFTMLVLMASLYVHMFLMARLHIKRIAVLPGTGTIRQGANMKGAITLTILIGVFVVCWAPFFLHLLFYISCPQNPYCVCFMSHFNLYLILIMCNAVIDPLIYALRSQELRKTFKEIICFYP-LGGICELPGRY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56450-1", "uniprot_id": "MC4R_MOUSE", "id": "P56450-1", "name": "Melanocortin receptor 4", "aln": "MNSTHHHGMYTSLHLWNRSSYGLHGNASESLGKGHPDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLN-STDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVRRVGIIISCIWAACTVSGVLFIIYSDSSAVIICLISMFFTMLVLMASLYVHMFLMARLHIKRIAVLPGTGTIRQGTNMKGAITLTILIGVFVVCWAPFFLHLLFYISCPQNPYCVCFMSHFNLYLILIMCNAVIDPLIYALRSQELRKTFKEIICFYP-LGGICELSSRY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32245-1", "uniprot_id": "MC4R_HUMAN", "id": "P32245-1", "name": "Melanocortin receptor 4", "aln": "MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLN-STDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYP-LGGLCDLSSRY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0V1P1-1", "uniprot_id": "MC4R_DANRE", "id": "B0V1P1-1", "name": "Melanocortin receptor 4", "aln": "MNTSHHHGLHHSFRNHSQGALPVG---KPSHGDRGSASGCYEQLLISTEIFLTLGLVSLLENILVIAAIVKNKNLHSPMYFFICSLAVADLLVSVSNASETVVMALITGGNLTNRESIIKNMDNVFDSMICSSLLASIWSLLAIAVDRYITIFYALRYHNIMTQRRAGTIITCIWTFCTVSGVLFIVYSESTTVLICLISMFFTMLALMASLYVHMFLLARLHMKRIAALPGNGPIWQAANMKGAITITILLGVFVVCWAPFFLHLILMISCPRNPYCVCFMSHFNMYLILIMCNSVIDPLIYAFRSQEMRKTFKEICCCWYGLASLCV-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .: *:*:: *:: .:.: : . * *. . .******::*.*:*:***::*********.**.********************:******.***:*::*:. .. *: :*: *:***:**:********* ***:******:******:****** :*.* **:***: *****:***:**:*::*:****:******.***********:****:****.***.*.* *.:*******:***:**************:: ****:************:********::*******:****:******* * : *..:* ", "identical_positions": 221, "similar_positions": 76, "identity": "66.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021223-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P33032-1", "uniprot_id": "MC5R_HUMAN", "id": "P33032-1", "name": "Melanocortin receptor 5", "aln": "MNSSF-HLHFLDLNLNATEG----NLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCRGFRIACSFPRRD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41149-1", "uniprot_id": "MC5R_MOUSE", "id": "P41149-1", "name": "Melanocortin receptor 5", "aln": "MNSSS-TLTVLNLTLNASED----GILGSNVKNKSLACEEMGIAVEVFLTLGLVSLLENILVIGAIVKNKNLHSPMYFFVGSLAVADMLVSMSNAWETVTIYLLNNKHLVIADTFVRHIDNVFDSMICISVVASMCSLLAIAVDRYITIFYALRYHHIMTARRSGVIIACIWTFCISCGIVFIIYYESKYVIICLISMFFTMLFFMVSLYIHMFLLARNHVKRIAASPRYNSVRQRTSMKGAITLTMLLGIFIVCWSPFFLHLILMISCPQNVYCSCFMSYFNMYLILIMCNSVIDPLIYALRSQEMRRTFKEIVCCHGFRRPCRLLGGY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A3KGQ1-1", "uniprot_id": "A3KGQ1_DANRE", "id": "A3KGQ1-1", "name": "Melanocortin receptor 5", "aln": "MNTSETTLPFWGMHVNSSPASYILNATETPSHNKPKACEQLNIATEVFLILGIVSLLENILVICAIVKNKNLHSPMYFFVCSLAVADMLVSVSNAWETIVIYLLTNRQLVVEDHFIRQMDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHNIMTVRRAALIIGGIWTFCTGCGIVFIIYSDNTSVIVCLVSMFFIMLALMASLYSHMFMLARSHVKRIAALPGYNSIHQRASMKAAVTLTILLGIFIVCWAPFFLHLILMISCPRNLYCMCFMSHFNMYLILIMCNSVIDPLIYAFRSQEMRKTLKEIICCYSLRNVFGMSR--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* * . .: :*:: . . :**. .**::.**.**** **::********* **************** **********:*.****:.****.*::**: * *:*::***************************:*********:***.**:. **. **:** .******:* :.. **:**:**** ** ::.*** ***:***.******* * .* :**:**:.*:*:*:***:* ***:****** **:***:*:** ***:*************:******:******:*:***:** .:* : ", "identical_positions": 212, "similar_positions": 70, "identity": "64.24%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021223-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35345-1", "uniprot_id": "MC5R_RAT", "id": "P35345-1", "name": "Melanocortin receptor 5", "aln": "MNSSSHLTLLDLTLNASEDNILGQNVNNKSSA---CEDMGIAVEVFLTLGLVSLLENILVIGAIVKNKNLHSPMYFFVGSLAVADMLVSMSNAWETITIYLINNKHVVIADTFVRHIDNVFDSMICISVVASMCSLLAIAVDRYITIFYALRYHHIMTARRSGVIIACIWTFCISCGIVFIIYYESKYVIVCLISMFFTMLFFMVSLYIHMFLLARNHVKRIAASPRYNS-VRQRASMKGAITLTMLLGIFIVCWSPFFLHLILMISCPQNVYCACFMSYFNMYLILIMCNSVIDPLIYALRSQEMRRTFKEIICCHGFRRTCTLLGRY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41149-1", "uniprot_id": "MC5R_MOUSE", "id": "P41149-1", "name": "Melanocortin receptor 5", "aln": "MNSSSTLTVLNLTLNASEDGILGSNVKNKSLA---CEEMGIAVEVFLTLGLVSLLENILVIGAIVKNKNLHSPMYFFVGSLAVADMLVSMSNAWETVTIYLLNNKHLVIADTFVRHIDNVFDSMICISVVASMCSLLAIAVDRYITIFYALRYHHIMTARRSGVIIACIWTFCISCGIVFIIYYESKYVIICLISMFFTMLFFMVSLYIHMFLLARNHVKRIAASPRYNS-VRQRTSMKGAITLTMLLGIFIVCWSPFFLHLILMISCPQNVYCSCFMSYFNMYLILIMCNSVIDPLIYALRSQEMRRTFKEIVCCHGFRRPCRLLGGY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P33032-1", "uniprot_id": "MC5R_HUMAN", "id": "P33032-1", "name": "Melanocortin receptor 5", "aln": "MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSP---CEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASS-ARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCRGFRIACSFPRRD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q9X6-1", "uniprot_id": "F1Q9X6_DANRE", "id": "F1Q9X6-1", "name": "Melanocortin receptor 5", "aln": "MNSS-EWPTLSPNSSLSQANLSDESSRPKTSASAACEQVHIAPEVFLTLGLISLLENILVILAIVKNKNLHSPMYFFVCSLAVADMLVSVSNAWETIVIHLLANRSLVIEDHFIRQMDNVFDSLICISVVGSMWSLLAIAVDRYVTIFYALRYHNIMTVRRAGILIGSIWTFSTSCGIIFIIYSDTQPVVVCLVAMFFAMLLMMASLYSHMFLLARSHVKRMAALPGYNANIRQRASMKGAVTLTILLGIFIVCWAPFFLHLILMISCPRNIYCVCFMSHFNMYLILIMCNSVIDPLIYALRSQEMRKTFKEIVCCEGLRSFCNMVSKY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** *. . . :: .: . . . *: . **:: ** *******::********* **************** **********:*.****:.*:*: *: :** * *:*::******:******.** **********:*********:***.**:* :*. **:*. .***:**:* :: *::**::***:**:::.*** *******.****:** * .: ***:**:**:*:*:***:* ***:****** **:***:*:** ***:*************:******:******:*****:**.*:* * : ", "identical_positions": 207, "similar_positions": 73, "identity": "62.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021226-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A4D0S4-1", "uniprot_id": "LAMB4_HUMAN", "id": "A4D0S4-1", "name": "Laminin subunit beta-4", "aln": "--MQFQLTLFLHLGWLSYSKAQDDCNRGACHPTTGDLLVGRNTQLMASSTCGLSRAQKYCILSYLEGEQKCFICDSRFPYDPYDQPNSHTIENVIVSFEPDREKKWWQSENGLDHVSIRLDLEALFRFSHLILTFKTFRPAAMLVERSTDYGHNWKVFKYFAKDCATSFPNITSGQAQGVGDIVCDSKYSDIEPSTGGEVVLKVLDPSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDALLGRRQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLT-CDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAPLNFYLYEAEEATTLQGLAPLG-----------------------------------SETFGQSPAVH--------------------------------------------------------VVLGEPVPGNPVTWTGPGFARVLPGAGLRFAVNNIPFPVDFTIAIHYETQSAADWTVQIVVNPPGGSEHCIPKTLQSKPQSFALPAATRIMLLPTPICLEPDVQYSIDVYFSQPLQGESHAHSHVLVDSLGLIPQINSLENFCSKQDLDEYQLHNCVEIASAMGPQVLPGACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLAANMEDKRETLPVCEADFKDLRGNVSEIERILKHPVFPSGKFLKVKDYHDSVRRQIMQLNEQLKAVYEFQDLKDTIERAKNEADLLLEDLQEEIDLQSSVLNASIADSSENIKKYYHISSSAEKKINETSSTINTSANTRNDLLTILDTLTSKGNLSLERLKQIKIPDIQILNEKVCGDPGNVPCVPLPCGGALCTGRKGHRKCRGPGCHGSLTLSTNALQKAQEAKSIIRNLDKQVRGLKNQIESISEQAEVSKNNALQLREKLGNIRNQSDSEEENINLFIKKVKNFLLEENVPPEDIEKVANGVLDIHLPIPSQNLTDELVKIQKHMQLCEDYRTDENRLNEEADGAQKLLVKAKAAEKAANILLNLDKTLNQLQQAQITQGRANSTITQLTANITKIKKNVLQAENQTREMKSELELAKQRSGLEDGLSLLQTKLQRHQDHAVNAKVQAESAQHQAGSLEKEFVELKKQYAILQRKTSTTGLTKETLGKVKQLKDAAEKLAGDTEAKIRRITDLERKIQDLNLSRQAKADQLRILEDQVVAIKNEIVEQEKKYARCYS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JHV6-1", "uniprot_id": "LAMB4_DANRE", "id": "Q8JHV6-1", "name": "Laminin subunit beta-4", "aln": "MLLRLELSALLLLLIAAPVRLQDECVGNSCYPNLGDLMVGRAAQLAASSTCGLYRPQNYCILGYLENERKCFTCDSRSPYNDYHNPSSHRIENIITTFQPERKMKWWQSENGVHEVSIQLDLEAMFQFSHLILTFKSFRPASMLVERSKDFGRTWKVFRYFAEDCANSFPGISEGPAHSIDDLVCDSRYSGAEPSTEGEVVLKALDPSFDIHDPYDSTIQGLITLTNLRVNFTRLLTLGDTLLTRRKRNPQDKYYYALYEMVVRGSCFCNGHASQCIPVDGARGDTFTEPGMVHGRCVCQHNTAGYNCERCQDFYHDAPWRPGGKADSDVCKRCNCHSHSEKCHFELARYLATGGVSGGVCDDCRNNRIGPQCELCGPFYYQDPQRSVDDPYACIPCDCDLDGSVDRGLCD--------PVNGQCVCKQNIEGERCDRCKVGFYGFSRDDPSGCQLCRCNFLGTIQVGNPCDPTTGRCICEHFAYGSQCDQCLPGYWGLGNTVYGCIPCDCDIGGALKTECSSVDGQCKCRPNMVGQKCNDPAPGYFLAPLDFYIYEAENAAPLAVISPFIGPPPFVYPTEGIPERPTKLPLCPPAPKPSSVPYREHITVQPSPAPHNPQVTLPMCEHYFRQRGYDFKISNGRLVVVKREKRQTRRRRQGQRTIPFEPGSPLQILLRQRANDQSITWTGLGFVRVQDGAGLRFTVSNIPATLDYYVVVRYEPESTDDWTAIVSILSIGSEDERCPNDQSNK--MFTLPASGRTATLDLPVCLSDGNQYHVDITFRKQPSEDPHSSSFILIDSLGLIPKVESVPNFCSQSYLSQFQQYRCIELAVQAGGQTLPEVCEMLIGSMSAFIHNGAVSCNCHHVGAYGSSCSKFGGQCQCKPNVIGRCCDSCAPLTYGLGPNGCSPCDCDRSGSTTELCDQTTGQCSCRDGITGLQCNRCYPGYYGFPLCRRCQCNRLADICDPITGDCLDCREHSAGRNCERCEEGYVGDPVSGQPCEPCLCPDLNGSGRFFAFSCNKDPRSGAPYCECLPGHTGPQCDSCSPGFYGDLRLPGGRCKECCCNNNIDPRDGDACDPVTGECLRCLHNTEGPRCQSCKRGYYGNALAQDCKECSCDRRGTDDSKCPAG-SPCFCDQDTGQCPCRPGVQGALCNECDDGYWNMDGDYGCQPCNCNREHALNYICDKITGQCLCQPEYGGRICDECGPNHFGNPDLQCMFCDCNLEGTVHPACDAYTGECLCKPGVTGPFCDECAPGHNNNFPACEPCHACNHLWEKIISDLSLDAERIETMMPCPEDFR-----SRPELQHLQNLLEKLQNVLN--MGAQDELKKLEELLARIRNETEIIDPNIIIIDPTLLLNTDIDYIRLEFNKLLKNLREKAKEGPVTDIKAVNDIFNKIKKFYDEFTDSEKKVEAAKKVQEASRKTREKVTLELAKCQIGEMDKLER--KVKALSAANINEEVCGAPGDAECEKAKCGGALCG------KCGGPDCTGSLPISLNASKLAEMTEKNITALRSQLKEADAQLRNASEMTSYVKDQAENMMDKINRTKTKYEQEKTDTKALIEKVKTYLQDELVKPEDIEKLANAVLSIQLPKSPDEIKDMIEDIKKILANITEFNDDLEYLEKQAKIAGNMKERAKEILNRT-ELINVKEIEKALNDTAKLHDKIFNDLDEAEQNNDVIREKVNETEPKLKNIEDHLNLTRAKT-LLDEIEALKNKTEMNRAQGKEAKDTADAALNSANDTGKDLEELKEQFEKLKLNSTNQNVSSEANERLKNITMEAENLAKHVEDKMKEIEDLEEKILLSNERKDEMRKELEALQKEADDLKKFIVDKVQRYNLCSP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::::*: :* * : : **:* .:*:*. ***:*** :** ******* *.*:****.***.*:*** **** **: *.:*.** ***:*.:*:*:*: ********:..***:*****:*:*********:****:******.*:*:.****:***:***.***.*:.* *:.:.*:****:**. **** ******.*****:*.:**.. **.*:******:***:* ****:** **:.:. **********:************:* *:: ***.*: ******:******* * *****:**::******... :.:.*: *.*:***.:***::: ***:**:*****:**::* * :*: * *::*:** :::.********:** **::. *:* .* ***:**:*:** :**:** ..**:* ** *** * ** **:: . . ** **:*:* :. *::*::* ******* ::** ********* .. **. :***:***::.*:.*.:******:***:**:****:*:.* ::*: *. *** * ::* : . .:.:**** **.** ******:*.*** .:*: :.::**.:*: ***. : : . *..:. *: ..* *:***: * * *:**. . ** :*: * : . :.*: *.:*:*******:::*: ****:. *.::* :.*:*:* * *.** .** ** **** :*:***:*:** *: *****::******** *:***** *:. :*.** :** **.*. .**. :***.****.*:. ::* :*:** .**:*** *: * ***:*::*** **.*::* .::******* :** *:* *****.****** .*.::**.** :: *. *:** *:**.**..**.****: *:.*. *: *.****** * ::*. ************:*..** ** *:**.** * *:.***. *.. :**.* ..*:** ** *** *.* * *:.* *****: . ***.*:*: . : . **::**** *: ***: *.** *::*:* :*: **** ** :* **. ** * *: **:* **.** **.::**:* ** * . *:: **.** .: : : . ** * ...:::.*:. :.:::.:*: : ...:: *::: :*.: :: :: : *: *: : * : **::*:*: . . . :: * ::***:*. :.:***:: :... ::* :**:.: * . .*** ::* . :**:*** **:. * ****** ** **.* ***.:* ** : *: ::. * * .*:: . *:.. ** :. *::* :: :*:.. :.: :.*: : : :*:***.:* :* * ******:**.**.*:** ..:::.* : .*:* : ::. * : *:::*. * :: :** : : *:*:.: : *::: :.: . : : * *:::* ::* : ::::..*:*:: :: * * :. *:.* : :: :. :** *::* :.*.. *:: ***:*: *: :::. .::.*: ::*::. **:** ..* *::.* ***.** * :: .:*. *:.:. :*: **:: ::* * .", "identical_positions": 778, "similar_positions": 568, "identity": "41.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021226-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAA7-1", "uniprot_id": "F1MAA7_RAT", "id": "F1MAA7-1", "name": "Laminin subunit gamma-1", "aln": "-MTGGRRAALALQLQRRLWLLLAVLAAVAC--WVRAAMD----------------ECADEGGRPQRCMPEFVNAAFNVTVVATNTCGTPPE-EYCVQTGVTGVTKSCHLCDAGQLHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPNSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASECVKN----EFGKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESANQCLPCDCNGRSQECYFDPELYRSTGHGGHCTNCRDNTDGAKCERCRENFFRLGNTEACSPCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGS---TDECNVETGRCVCKDNVEGFSCERCKPGFFNLESSNPKGCTPCFCFGHSSVCTNAVGYSVYDISSTFQIDEDGWRVEQRDGSEASLEWSSDRQDIAVISDTYFPRYFVAPAKFLGNQVLSYGQNLSFSFRVDRRDTRLSAEDLVLEGAGLRVSVPLIAQGNSYPSETTVKYIFRLHEATDYPWRPALSPFEFQKLLNNLTSIKIRGTYSERSAGYLDDVTLQSARPGP-GVPATWVESCTCPVGYGGQFCETCLPGYRRETPSLGPYSPCVLCTCNGHSETCDPETGVCDCRDNTAGPHCEKCSDGYYGDSTLGTSSDCQPCPCPGGSSCAIVPKTKEVVCTHCPTGTAGKRCELCDDGYFGDPLGSNGPVRLCRPCQCNDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKEGFFGNPLAPNPADKCKACACNPYGTVQQQ---SSCNPVTGQCQCLPHVSGRDCGACDPGFYNLQSGQGCESCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCETNHFGFGPEGCKPCDCHHEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECPACYRLVKDKVAEHRVKLQELESLIANLGTGDETVTDQAFEDRLKEAEREVTDLLREAQEVK-DVDQNLMDRLQRVNNSLHSQISRLHNIRNTIEETGILAERARSRVESTEQLIEIASRELEKAK--------MAAANVSITQPESTGEPNNMTLLAEEARRLAERHKQEADDIVRVAKTANETSAEAYNLLLRTLAGENQTALEI-EELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLTP--VDSEALESEANKIKKEAADLDRLIDQKLKDYEDLREDMRGKEHEVKNLLEKGKAEQQTADQLLARADAAKALAEEAAKKGRNTLQEANDILNNLKDFDRRVNDNKTAAEEALRRIPAINRTIAEANEKTREAQLALGNAAADATEAKNKAHEAER-IASGVQKNATSTKADAERTFSEVTDLDNEVNGMLRQLEEAENELKRKQDDADQDMMMAGMASQAAQEAELNARKAKNSVSSLLSQLTDLLEQLGQLDTVDLNKLNEIEGSLNKAKDEMKVSDLDRKVSNLENEARKQEAAILDYDRDIAEIIKDIHNLEDIKKTLPTGCFNTPSIEKP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P02468-1", "uniprot_id": "LAMC1_MOUSE", "id": "P02468-1", "name": "Laminin subunit gamma-1", "aln": "-MTGGGRAALALQPRGRLWPLLAVLAAVAG--CVRAAMD----------------ECADEGGRPQRCMPEFVNAAFNVTVVATNTCGTPPE-EYCVQTGVTGVTKSCHLCDAGQQHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPNSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNEPKVLKSYYYAISDFAVGGRCKCNGHASECVKN----EFDKLMCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASESLPCDCNGRSQECYFDPELYRSTGHGGHCTNCRDNTDGAKCERCRENFFRLGNTEACSPCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDLRGS---TDECNVETGRCVCKDNVEGFNCERCKPGFFNLESSNPKGCTPCFCFGHSSVCTNAVGYSVYDISSTFQIDEDGWRVEQRDGSEASLEWSSDRQDIAVISDSYFPRYFIAPVKFLGNQVLSYGQNLSFSFRVDRRDTRLSAEDLVLEGAGLRVSVPLIAQGNSYPSETTVKYIFRLHEATDYPWRPALSPFEFQKLLNNLTSIKIRGTYSERTAGYLDDVTLQSARPGP-GVPATWVESCTCPVGYGGQFCETCLPGYRRETPSLGPYSPCVLCTCNGHSETCDPETGVCDCRDNTAGPHCEKCSDGYYGDSTLGTSSDCQPCPCPGGSSCAIVPKTKEVVCTHCPTGTAGKRCELCDDGYFGDPLGSNGPVRLCRPCQCNDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKEGFFGNPLAPNPADKCKACACNPYGTVQQQ---SSCNPVTGQCQCLPHVSGRDCGTCDPGYYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCETNHFGFGPEGCKPCDCHHEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECPACYRLVKDKAAEHRVKLQELESLIANLGTGDDMVTDQAFEDRLKEAEREVTDLLREAQEVK-DVDQNLMDRLQRVNSSLHSQISRLQNIRNTIEETGILAERARSRVESTEQLIEIASRELEKAK--------MAAANVSITQPESTGEPNNMTLLAEEARRLAERHKQEADDIVRVAKTANETSAEAYNLLLRTLAGENQTALEI-EELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLTP--VDSEALENEANKIKKEAADLDRLIDQKLKDYEDLREDMRGKEHEVKNLLEKGKAEQQTADQLLARADAAKALAEEAAKKGRSTLQEANDILNNLKDFDRRVNDNKTAAEEALRRIPAINRTIAEANEKTREAQLALGNAAADATEAKNKAHEAER-IASAVQKNATSTKADAERTFGEVTDLDNEVNGMLRQLEEAENELKRKQDDADQDMMMAGMASQAAQEAELNARKAKNSVSSLLSQLNNLLDQLGQLDTVDLNKLNEIEGSLNKAKDEMKASDLDRKVSDLESEARKQEAAIMDYNRDIAEIIKDIHNLEDIKKTLPTGCFNTPSIEKP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11047-1", "uniprot_id": "LAMC1_HUMAN", "id": "P11047-1", "name": "Laminin subunit gamma-1", "aln": "-MRGSHRAAPALRPRGRLWPVLAVLAAAAAAGCAQAAMD----------------ECTDEGGRPQRCMPEFVNAAFNVTVVATNTCGTPPE-EYCVQTGVTGVTKSCHLCDAGQPHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPSSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASECMKN----EFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGS---IDECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTNAVGYSVYSISSTFQIDEDGWRAEQRDGSEASLEWSSERQDIAVISDSYFPRYFIAPAKFLGKQVLSYGQNLSFSFRVDRRDTRLSAEDLVLEGAGLRVSVPLIAQGNSYPSETTVKYVFRLHEATDYPWRPALTPFEFQKLLNNLTSIKIRGTYSERSAGYLDDVTLASARPGP-GVPATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQ---SSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECPACYRLVKDKVADHRVKLQELESLIANLGTGDEMVTDQAFEDRLKEAEREVMDLLREAQDVK-DVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAEQARAHVENTERLIEIASRELEKAK--------VAAANVSVTQPESTGDPNNMTLLAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFEI-EELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLSP--LDSETLENEANNIKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAINQTITEANEKTREAQQALGSAAADATEAKNKAHEAER-IASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLLSIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAKKQEAAIMDYNRDIEEIMKDIRNLEDIRKTLPSGCFNTPSIEKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LVF0-1", "uniprot_id": "LAMC1_DANRE", "id": "Q1LVF0-1", "name": "Laminin subunit gamma-1", "aln": "---------MSLFSCLLLWTLWAA--------CSHGAMD----------------ECIDEDDRPQRCMPEFVNAAFNATVVATNTCGSPPE-EFCVQTGVTGVTKSCHICNAADPRLHHGAVYLTDYNQPVQPTWWQSQTMLAGIQYPNSINLTLHLGKSFDITYVRLKFHTSRPESFAIYKRSSEDGPWTPYQYYSGSCEKTYSKNNRGFIRTGEDEQQALCTDEFSDISPLYGGNVAFSTLEGRPSAYNFDNSPVLQDWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASECVKN----EYSKLVCNCKHNTEGADCNVCKPFYNDRPWRRATAENPNECLPCNCNGKSAECYFDPELYRATGHGGHCRNCADNTDGPKCERCLANYYREASGQRCLSCGCNPVGSLSTQCDNTGRCSCKPGVMGDKCDRCQPGYHSLSEAGCRPCSCNPAGS---TQECDVQTGRCQCKENVDGFNCDRCKLGYFNLDPQNPQGCTPCFCFQHSTVCESADGYSVHKITSTFDRDDEGWKGKQRDDSSVPVQWSPSSGEISLISEDYFPIYFVAPDKFLHNQLLSYGQNLTLNFRIQRHDARLSAEDVVLEGSGLRVAVPLIAQGNSYPGEETQTFVFRLHDTTDYPWRPTIKHADFQKLLYNLTSIMIRGTYSAQSAGYLDNVSLVTARRGP-GTPARWVEKCTCPQGYLGQHCEQCDQGFRRSRPELRRFSTCERCNCNGHSDTCDPETGMCNCQHNTAGLSCERCKDGFYGDSTVGSSSDCKACPCPAGATCAVVPKTNEVVCTNCPTGTTGKRCELCDDGFFGDPLGEKGPVRACRACSCNNNIDPNAVGNCNRESGECLKCIYNTAGVFCDRCKQGFYGDARAANVADKCKPCKCSPYGTVDRQ---TACSQVTGQCPCLPHVINRDCGACELGFYNLQSGKGCERCNCNPIGSTNGQCDIVSGQCECQPGVTGQHCERCEVNFFGFSSSGCKPCDCDPEGSESAQCKEDGRCHCRPGFVGSRCDMCEENYFYNRSTPGCQQCPNCYSLVRDKVNQQRQKLLDLQNLIDSLDNTETTVSDKAFEDRLKEAEKTIMDLLEEAQASK-EVDKGLLDRLNNINKTLNNQWNRLQNIKNTVDNTGAQADRARNRVRDAENLINTAREELDKAK--------EAISKVDIKIPTTSGDPNNMTLLAEEARKLSEKHKADADQIEKIAKDANDTSTKAYNMLKKALDGENKTSSDI-DELNRKYLEAKDLAKNLEKQAAKVHAEAEEAGNKALKIYANLTSLPP--INTKTLEDDANKIKKEASDLDKLIDKTEKEYNDLREDLRGKETEVRKLLDKGKTEQQTADQLLARADAAKALAEEAAKKGKSTFQEAQDILNNLRDFDKRVNDNKTAAEDAMRRIPQINATINEANDKTRRAEAALGNAAADAKDAKAKAEEAEK-IANDVQKGSAKTKADAEKAFEDTMKLDKDVDKMMDQLTAAEKELEKKKAEADTDMMMASMASDNAKDAEGNARKAKSAVREVLNTINALLGQLGNIDKVDLSKLNQIDNALKDAKDKMAGSELDRKLKELNDIAKSQEDMISDYDRQIQEIRADIANLNDIKNTLPEGCFNTPSLERP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15215-1", "uniprot_id": "LAMC1_DROME", "id": "P15215-1", "name": "Laminin subunit gamma-1", "aln": "MKRSRWSHSGSSTARLLLIGVLFASCSTAILGAQRPPINSAGGHELRGTTFMPALECYDPYGRPQKCLPEFINAAYQLQIESTNTCGEQNDNHFCIQT-MNQNHKNCEFCKYN----DHNPSFLTDLHDPQSPTWWQSETMFEGIQHPNYVNLTLHLGKSYDITYVRILFRSPRPESFTIYKRTSESGPWIPYQFYSATCRDTYSLPDSRAIRKGEGEAHALCTSEYSDISPLRDGEIAFSTLEGRPSGINFERSGELQEWVTATDIRITLDRLNTFGDELFGDSQVLKSYFYAISDIAVGARCKCNGHASKCVPSTGMHGERTLVCECRHNTDGPDCDRCLPLYNDLKWKRSTSTEVNECKACNCNGLADKCFFDANLFNRTGHGGHCLDCRENRDGPNCERCKENFYMRDDG-YCVNCACDPVGSRSLQCNSHGKCQCKPGVTGDKCDRCDNNYYQFGPHGCQQCGCDSGGSHQNTPACDTETGICFCKENVEGRRCNECKPGFFNLDKNNRFGCTPCFCYGHTSECMTAPGYSIVSVTSNFNKFKERWTAADLNQREVDIKYNQYSRSIGTTAQGNEHVYFQAPDRFLGDQRASYNRDLKFKLQLVGQVANTGVSDVILEGAGSRISLPIFAQGNGIPDQGVKEYTFRLHEHHDYQWQPSQSARGFLSILSNLTAIKIRATYSVQGEAILDDVELQTAHRGAAGHPATWIEQCTCPEGYLGQFCESCAPGYRHSPARGGPFMPCIPCDCHGHADICDSETGRCICQHNTHGDNCDQCAKGFYGNALGGTPNDCKRCPCPNDGACLQIN-EDTVICTECPKGYFGSRCEQCSDGFFGDPTGLLGEVQTCKSCDCNGNVDPNAVGNCNRTTGECLKCIHNTAGEHCDQCLSGHFGDPLAL-PHGRCDRCSCYEAGTEQDEQSITRCDQVTGQCQCKPNVIGRDCGECQPGYFNIRSGNGCENCLCDPVGSYNSTCDRYSGQCHCRPGVMGQRCDQCENYFYGFSSEGCKPCECDESGSKGFQCDQNGQCPCNDNVEGRRCDRCKEN-KYDRHR-GCIDCPDCYNLVQDAADLHRAKLFNLSQTLDEIAR-TPVTNDDEFEAKLKAVQEKVAVLAQDARDNSGDGGQTYAEVIDDLHKHLDSVREHLVSADKFQADANGEIDRARQNYTILDQITENAKKELQQALDLLNDEGAQALARAKEKSVEFGQQSEQISDISREARALADKLESEAQFDLKNAKDAKDAVEKAHQLAKSAIDLQLKIGTELRSEVGLELSHVKQSLGTVVQTSKEALRKANEVYDTALTLLNDVNRQTQPEIDISQLKKDAVAANERADELLKQITELSNSNGELFADFETEQELTEALLKRAEQQQLEDIELLERAKAAHDKATKAVEQGDNTLKEANNTYEKLAGFQSDVQRSSESAEKALQTVPNIEKEIQNAESLISQAEEALDGANKNANEAKKNAQEAQLKYAEQASKDAELIRRKANETKVAARNLREEADQLNHRVKLTEMDIFKLEESSTKDDNLVDDAKRKVGQAKADTQEAQKQIEKANADLTAIKDELENLKDINTGDLDRLENRLATVEGEINRVNLTGRIEKYREQRTIQKNLIDKYDAELRELKDEVQNIGLISKALPDSCFSRNRLEP-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : . : .:: ** * .***:*:***:***:: : :***** : .:*:** :. *.*.:*. .*.. :*** :: ..*****:**: *:*:*. :********::******: *::.*****:****: *.*** ***:**.:*..*** : **.* .* :****.*:****** .*::**********. **:.* **:********:**:********:*.:.:*****:*****:***.*********:*: . .*:*:*:*** * **: * *::** *:*:*: . .:. .*:*** : :*:**.:*:. ******* :* :* **.:**** *:: . * * *.**** * **:. *:*.***** *******: .::.: **: *.*: ** *: :** * **:**:* *:.** *:***: .* *******: *:: * .* ***: .::*.*: .: * : : .. :::. .*. :: ** ** :** .* **.::*.:.::: : :. ...*::***:* *:::*::****. *.: . : ****: ** *:*: . * .:* ***:* **.*** : . **:* * :*: *. * ** *:*.**** ** **.** * *:*:. . : .* * *:**:: **.*** * *:.** * *::* .*:**:: *:..**: **** ..:* : . *:**.**.* *.*** *.**:**** * * *: *: *.*..*:********** :*******:**** .**:* .*.:*:. * .:*. * * ** . : : *. ***** * *:* .:*** *: *::*::**:*** * *..:** *. ** :***.*:**: **:*::** .:**...*****:*. .** . **.::*:* *. .. * *** *:** *:* ** :** ** **:* . :* ** :*.. : .: ..*. ** :** .:. : * .:*: . : .: : :: ::. * . .:* . : ::. ::** . :.: : * .**::* * :... . :.:::: ::.*** *::: : :*: : ** *::: :*::: :: : : . :: .*:. : ..*: : : : .. :*:.. :.*: : .: . :: . *:.:* : .* :* : * : :. :* *:. :: .. **.:.: :* :** **.**: * :*.::* .*::**:: ::* .*: *: .. :**.*:: :* *: * :*:. .*: **..* :*.:** :*.**: *. ..*.: : .*:.: . .* ::.: : :: :* :: : : .: * :.. *. . :*: ::::*:. : . :. : :* ::. :: ..*:.::. * .:.:: :* ::.. .. *: * .*: :: *: :: *: * ::** .**. :* ", "identical_positions": 572, "similar_positions": 549, "identity": "34.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021231-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A4W3-1", "uniprot_id": "A0A8I6A4W3_RAT", "id": "A0A8I6A4W3-1", "name": "Pre-rRNA-processing protein TSR2 homolog", "aln": "-------------------MMAGAAEDVRLLFGAGVRAALEAWPALQIAVENGFGGVHSQEKAEWLGGAVEDYFIANADLELEEIEDFLGELMTTEFDTVVEDGSLPQVSQQLQTMFHHFQKGDGAALQEMTSHINQKKCKVTATPLKTAKETD----VAEDDVDSVEEMEVTATNDGATTDGVCPQSQPSDPDSQTIKEEDIVEDGWTIVRRKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C8T8-1", "uniprot_id": "TSR2_MOUSE", "id": "Q8C8T8-1", "name": "Pre-rRNA-processing protein TSR2 homolog", "aln": "--------------------MAGAAEDVRVLFGAAVRAALEAWPALQIAVENGFGGVHSQEKAEWLGGAVEDYFIANADLELEEIEDFLGELMTTEFDTVVEDGSLPQVSQQLQTMFHHFQKGDGAALQEMTSQINQKKCKVTATPLMTAKETD----VAEDDVDSVEEMEVTATNDGATTDEVCPQPQPSDPDTQTIKEEDIVEDGWTIVRRKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969E8-1", "uniprot_id": "TSR2_HUMAN", "id": "Q969E8-1", "name": "Pre-rRNA-processing protein TSR2 homolog", "aln": "--------------------MAGAAEDARALFRAGVCAALEAWPALQIAVENGFGGVHSQEKAKWLGGAVEDYFMRNADLELDEVEDFLGELLTNEFDTVVEDGSLPQVSQQLQTMFHHFQRGDGAALREMASCITQRKCKVTATALKTARETD----EDEDDVDSVEEMEVTATNDGAATDGVCPQPEPSDPDAQTIKEEDIVEDGWTIVRRKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3KRG3-1", "uniprot_id": "TSR2_DANRE", "id": "Q3KRG3-1", "name": "Pre-rRNA-processing protein TSR2 homolog", "aln": "--------------------MAPLSSSTREVFSEAVRAVLETWPVLQIAVDNGFGGAFSQQKAEWMVDALQQYFTDNGDLQPDEVEDFISELMNNEFDTVVDDGSLPQVAQQVCGMFQQCEQGRLAEVREQILKLNQKK-TSSGRAKATPAQTP----QDDDDDDEEEAMDCEGGSAGASVSSTAVN------DLHHEEEE---DDGWTVVRRKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBI0-1", "uniprot_id": "Q9VBI0_DROME", "id": "Q9VBI0-1", "name": "Pre-rRNA-processing protein TSR2 homolog", "aln": "-------------------MAAAQQTEFQKNFRVIVEKIFNHWQDLRLAVEHGMGGRNGQQVAIEIMDYTYQYCVSNENITQGELVEVLEELMDQEFNTLCDDDSIPEICRNLLRYKLMAQQNQFPQIEAELSKLPAGKEWLRPDVKITYTPIDGDSSSDEDMDDSDEEDDNEMGQGDEETPSGSGRMTRSQARKQQAEEFVEPEDGWTTVRRK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06672-1", "uniprot_id": "TSR2_YEAST", "id": "Q06672-1", "name": "Pre-rRNA-processing protein TSR2", "aln": "MSTQYIDETAFVQAEQGKTNLMFSDEKQQARFELGVSMVIYKWDALDVAVENSWGGPDSAEKRDWITGIVVDLFKNEKVVDAALIEETLLYAMIDEFETNVEDDSALPIAVEVINIYNDCFNLNYNKVEKLYLEWQEKQRTKKS---KRVVHIE-----GDDDEDDEDVEDYDDEDEDEEMDEVVPDLVSS--KPEPIVDEDGFELVQPKGRRKH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * * : * * :**::. ** . : : . : : : : : : : **:* :*.* :. :: . :. : :* *. : : . . . : : . *** ", "identical_positions": 18, "similar_positions": 39, "identity": "8.37%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-021231-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91VE6-1", "uniprot_id": "MK67I_MOUSE", "id": "Q91VE6-1", "name": "MKI67 FHA domain-interacting nucleolar phosphoprotein", "aln": "-MAGLAG---PAKPSLALNPQEDSQFEKALT--QIQGRTKKPQQKKKEKLN--------------------------------------RGVVYLGHLPSTLSESHIYNYCAQFGDISRFRLSRSKRTGNSKGYAFVEFESEDVAKIVAETMDNYLFGERLLSCKFMPRKKVHKDLFSQ-------------RNALFHRPSFPAVKRYNRKRGHLQMLKMEYRFKKKEKLLRKKLAAKGIDYS--FPSLVLPKPKNIAVAHRDSEGNQVLPDQKEGLSGEPRRKEKMMKEDISNNIPKKRKRSRRKKSSVDSQGPTPVCTPTFLERRKSQVMEVGGD-KDDEIILKLPVPPVKEDTQKTPTSASPGGKRPRKRKSKQ--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5RJM0-1", "uniprot_id": "MK67I_RAT", "id": "Q5RJM0-1", "name": "MKI67 FHA domain-interacting nucleolar phosphoprotein", "aln": "-MAEYSG---PAKPTLALNPREDSQFEKDLT--QIQRRAKK---KKEEKLN--------------------------------------SGVVYLGHLPSTLSESHIYDYCAQFGDIRRFRLSRSKRTGNSRGFAFVEFESEDVAKIVAETMDNYLFGERLLSCKFMPREKVHKDLFNQ-------------CNVPFHPPSFPAVKRYNQKRGHLQMLKMEYRFKKKEKLLRKKLAKKGIDYS--FPSLVLPKPKKEISSIANTHGD-----------------------------------------SEANQDPTPVCTPTFLERRKSQLMEIN---DDDEIILKLPVSPVKEDTQKTPAPESSGKKRLRKRKSKQ--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BYG3-1", "uniprot_id": "MK67I_HUMAN", "id": "Q9BYG3-1", "name": "MKI67 FHA domain-interacting nucleolar phosphoprotein", "aln": "-MATFSG---PAGPILSLNPQEDVEFQKEVA--QVRKRITQ--RKKQEQLT--------------------------------------PGVVYVRHLPNLLDETQIFSYFSQFGTVTRFRLSRSKRTGNSKGYAFVEFESEDVAKIVAETMNNYLFGERLLECHFMPPEKVHKELFKD-------------WNIPFKQPSYPSVKRYNRNRTLTQKLRMEERFKKKERLLRKKLAKKGIDYD--FPSLILQKTESISKTNRQTSTKGQVLRKKK---------------------KKVSGTLDTPEKTVDSQGPTPVCTPTFLERRKSQVAELNDDDKDDEIVFKQPISCVKEEIQETQTPTHSRKKR--RRSSNQ--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JIY8-1", "uniprot_id": "MK67I_DANRE", "id": "Q8JIY8-1", "name": "MKI67 FHA domain-interacting nucleolar phosphoprotein", "aln": "-MTEGKSSDKPAKRLLALNPKEDAEFQKKVQ--QVKKRPQT-----GQTLS--------------------------------------PGVLYVGHLPRGLFEPQLKSYFEQFGKVLRLRVSRSKKTGGSKGYGFVEFECDEVAKIVAETMNNYLMGERIIKCHVIPPEKVHEKLFVG-------------SIAGFKKPKYPAVTRYNKTHTEDDVKKVGTKLLSKESKLRKRLAAKGIDYD--FPGFAAQIPAKKAPSEAN--------------------------------------------VSVCSEDVTPVCTPSLLERRKS--LRVEDDDVDDEIVIKVKPLPENSDDVEESEEESAEEDEGEEEEAA---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCY1-1", "uniprot_id": "Q9VCY1_DROME", "id": "Q9VCY1-1", "name": "RRM domain-containing protein", "aln": "-MPPVKKP-KAQKIEKQSTPKKPIDAAKNVVSGQLKKKVTKARPQKPKGPE--------------------------------------RGVVIVKHLPHGFFEQQLRQYFRQFGRVLRVRLARSLRTGNSKGYAFVEFEYPEVAKVAADTMDNYLMFQKVVKATYIPPEKQTLNFFRTSLKKVVNKAGKEIYVSDLTKATQRSVKKQN-NWDESACQKRTVANLNKIKKLQEKYKDLGIDFSNLLVEPVKKAAGSAEASTSQAAAKKAGKKQKTAAKKEPTLEDLLGNTINEDSDDEDYVDASDDESDLEAEEEQADSEQTSDDSDEEEDLSPPPKQKKTKLADKLKRKPGTGGVQKKKIAPPAKSNKNAATQKLQLAAAKSLAKPLPKGKAKKSK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53927-1", "uniprot_id": "NOP15_YEAST", "id": "P53927-1", "name": "Ribosome biogenesis protein 15", "aln": "MVKSTSKTSTKETVTKQPTEEKPIQEKEELALETSSSSSDEEDEKDEDEIEGLAASDDEQSGTHKIKRLNPKKQANEKKSKDKKTLEEYSGIIYVSRLPHGFHEKELSKYFAQFGDLKEVRLARNKKTGNSRHYGFLEFVNKEDAMIAQESMNNYLLMGHLLQVRVLPKGAKIEKLYKY------------------------KKRVLVEKGITKPVKQLKDNMKQKHEERIKKLAKSGIEFKW---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .: : : : . *:: : :** : * .: .* *** : ..*::*. :**.*: :.*:** : * :. ::*:***: :::. :* .:: . : .* :: **::. ", "identical_positions": 25, "similar_positions": 51, "identity": "6.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030102-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P3X3-1", "uniprot_id": "TTC27_HUMAN", "id": "Q6P3X3-1", "name": "Tetratricopeptide repeat protein 27", "aln": "----MWTPELAILRGFPTEAERQQWKQEGVVGSESGSFLQLLLEGNYEAIFLNSMTQNIFNSTTTAEEKIDSYLEKQVVTFLDYSTDLDTTERQQLIFLLGVSSLQLFVQSNWTGPPVDLHPQDFLSSVLFQQFSEVKGLDAFVLSLLTLDGESIYSLTSKPILLLLARIILVNVRHKLTAIQSLPWWTLRCVNIHQHLLEERSPLLFTLAENCIDQVMKLQNLFVDDSGRYLAIQFHLECAYVFLYYYEYRKAKDQLDIAKDISQLQIDLTGALGKRTRFQENYVAQLILDVRREGDVLSNCEFTP--APTPQEHLTKNLELNDDTILNDIKLADCEQFQMPDLCAEEIAIILGICTNFQKNNPVHTLTEVELLAFTSCLLSQPKFWAIQTSALILRTKLEKGSTRRVERAMRQTQALADQFEDKTTSVLERLKIFYCCQVPPHWAIQRQLASLLFELGCTSSALQIFEKLEMWEDVVICYERAGQHGKAEEILRQELEKKETPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKDVQVLKILVRAVIDGMTDRSGDVATGLKGKLQELFGRVTSRVTNDGEIWRLYAHVYGNGQSEKPDENEKAFQCLSKAYKCDTQSNCWEKDITSFKEVVQRALGLAHVAIKCSKNKSSSQEAVQMLSSVRLNLRGLLSKAKQLFTDVATGEMSRELADDITAMDTLVTELQDLSNQFRNQY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CD92-1", "uniprot_id": "TTC27_MOUSE", "id": "Q8CD92-1", "name": "Tetratricopeptide repeat protein 27", "aln": "MPGMMWTPELALLRGFSTEAERLVWKQEGICGSDIGVFLELLLEGSYEALFFHSTTQTILNSTMMAEEKIDSYLEKQIVNFLDCSTDLEEIERQQLVFLLGVSSLQLFVQSNWTGPLVDLHPQDFLPSGLLEQFSEVKGLDAIIMGLLILDGESVYSLTSKPILLLIARIILVNIRHKLTALQSLPWWTLRYVNIHQQLLEERSPQLFALAKNCIDQVMKQENLFEGDSGRLLAIQFHLECAHVFLYYYEYKEAKDQFSTAKDISKLEIDLTGALGKRTRFQENYVAQLIVDVRRKEAVPFSCEFSP--APTPQECLAKNLELNDDTVLNEIKLADSERFQMPDLCAEELAVVLGVCTNFQKNNPVHKLTEEELLAFTSCLLSQPKFWAIQMSALILRTKLERGSTRRVERAMRQTQALADQFEDKATSVLERLKIFYCCQVPPHWAVQRQLAGLLFELGCTSSALQIFEKLEMWEDVVICHERAGRHGKAEEILRQELEKKETPGLYCLLGDVLQDHSCYDKAWELSRHRSARAQRSKALLHLRNKEFRECVECFERSVKINPMQLGVWFSLGCAYLALEDYGGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFGEAIKAYHRLLDLRDKYKDIQVLKILVQAVVNDMTDRSGAVASSLKGKLQELFGRITSRVTNDGEVWRLYAQVHGNGQSEKPDENDKAFQCLSKAYKCDTQSSCWEKDATAFKEVVQRAIGLAHVAMKCAESKSIPQEAVQTLSSVRLNLRGLLSKAKQNFTDVVSGEVSGELASEIAAVNALEAELQDLSNQLRNRY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "K7DY99-1", "uniprot_id": "K7DY99_DANRE", "id": "K7DY99-1", "name": "Tetratricopeptide repeat protein 27", "aln": "----MLQLEAAVLGGLS-----LDWKQSSFSTADAGSLLQLVYDGDFEAVLFSSAVQGLLGVCPEEGDSIEAYLERQVLSYLSDATEEQRSHREVALLAVAVGCLNLFAQSNWTGPPVELHVSDVLPEALLQNFSQPAALSTALLSSLQLDGESVYSLVSNPLLLLLTRVIFVNCAAKLESLQLLPWWTLRYVALHQQILEERSPQLLNLMLSCIEKVCKCDELFSSNAHRNLAIQFHLECSYICLTYYEYHKAKEHLQTARDLSGLDVNMTGALGKRTRFQENFLAQLILDVKRKDNSPFYNSESPSSTPTPKELLPKDHQLSDDTVLNQINLAEPSEHELPDLSAEEQAFILATCTDFQKNNPVHKLNDEELLAFTTCLLSQPKFWAVEVTSLCLRTKLERGSSRRVERAMMQTQTLVDFFSEKDCPVTERLKMFYSCRAPPLWDLQRQLASLLTDLGLTSSALLIYERLELWEDAVVCLERMGQHGKAEEILRRELEKKETPSLYCLLGDVLKDPQYYDRAWELSKHRSARAQRSKALHHLRHREFQQCVECFERSLQINSMQLGVWFSLGCAYFALESYEGAARAFQRCVGLEPDNSEAWNNLSTAYIKLRVKEKAFRTLQEALKCNYERWQIWENFIAVCVDLGEFSEAIRAYHRLMELKDKYKDVEVLEILVQAVVDNLTDHRGEQASILRPKLQELLGRVSSRCSTDAQIWKQYARLYGDGHSNNAEDNEKALQFLSKAHRCETQAAGWEKDTGSFKSVVKGARDMANVSISCSRSKRSPQEALQLLSSARLSLKSLTTKARQLYTDVATGELHDDLRDDVIELEQLITEIQDLSAQLRSQ-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * *:* *:. ***... :: * :*:*: :*.:**::: * .* ::. :.*::***:*::.:*. :*: : .*: :: :.*..*:**.******* *:** .*.*.. *:::**: .*.: ::. * *****:***.*:*:***::*:*:** ** ::* ******* * :**::****** *: * .**::* * ::** .:: * *********::: * ****::**:::. *:*:* *::::*************::****:**:*: . :* :***:* *.*: :*.***:**:*:**: ...::***.*** *.:*. **:********.*.: ******:**********:: ::* ******:**:******* ***:*.* *.:* .* ****:**.*:.** * :*****.** :** ***** *:*:**:***.*:* ** *:*********:********.********* * . **:*****::*********** ***::**::********::**.*************:***.* *:*:****** *****:********:**:*: * ***************:******:* ...*:***.***:*****::*:*****::**:***:**::.:**: * *: *: *****:**::** :.*.::*: **:::*:*:*::.::*:**:* ****::*:**: **** :**.**: * .:*:*::.*:..* .***:* ***.**.*:.* :**:* :***.:**: :* .:: :: * :*:**** *:*.: ", "identical_positions": 463, "similar_positions": 254, "identity": "54.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030102-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P40507-1", "uniprot_id": "AIR1_YEAST", "id": "P40507-1", "name": "Protein AIR1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTLLSEVESIDTLPYVKDTTP---TGSDSSSFNKLLAPSIEDVDANPEELRTLRGQGRYFG---------------ITDYDSNGAIMEA------------------------------------------------------------------EPKCNNCSQRGHLKRNCP---HVICTYCGFMDDHYSQHCPKAIICTNCNANGHYKSQC-PHK-WKKVFCTLCNSKRHSRERCPSIWRSYLLKTKD--ANQGDFD---FQTVFCYNCGNAGHFGDDCAERRSS--------------------------------------RVPNTDGSAFCGDN---------LATKFKQHYFNQLKDYKREASQRQHFDN---------------EHEFNLLDYEYNDDAYDLPGS----------RTYRDKMKWKGK----------VQSTRNKNSSNNRYESSNNRK--KKSPFSAQNYKVTKNKRVQTHPLDFPR------SSQNNRTNDYSSQFSYNRDDFPKGPKNKRGRSSS-NKSQRNGRY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12476-1", "uniprot_id": "AIR2_YEAST", "id": "Q12476-1", "name": "Protein AIR2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKNTAPFVVDTAP---TTPP----DKLVAPSIEEVNSNPNELRALRGQGRYFG---------------VSDDDKD-AIKEA------------------------------------------------------------------APKCNNCSQRGHLKKDCP---HIICSYCGATDDHYSRHCPKAIQCSKCDEVGHYRSQC-PHK-WKKVQCTLCKSKKHSKERCPSIWRAYILVDDNEKAKPKVLP---FHTIYCYNCGGKGHFGDDCKEKRSS--------------------------------------RVPNEDGSAFTGSN---------LSVELKQEYYRHMN---------RNSDE---------------NEDYQFSESIYDEDPLPRPSH----------KRHSQNDHSHSG----------RNKRRASNFHPPPYQKSNVIQPTIRGETLSLNNNISKNSRYQNTKVNVSS------ISENMYGSRYNPSTYVDNNSISNSSNYRNYNSYQPYRSGTLGKRR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "B1WC15-1", "uniprot_id": "ZCHC7_RAT", "id": "B1WC15-1", "name": "Zinc finger CCHC domain-containing protein 7", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFGGFETIEAFEDDLYRD--DSSSELSVDSEVEFQLYSQVHYSQNIHNANEEEGYEE----KNCESSETVSIQPDQKNLIVLSDSEVIQLSDTSEVITLSDEDSIYRCKRKNIEVQAQEKTQSPATPRSNK--VANKCKRSNKKPEPEESPSTIREVMIIEVSSDEEEESTISENENVESWMLLGCEEDDKDNDILLNLVGCKDAGAEGENDVN------WFISDKDIEAKIDNN---------------------------------------------------RSSGRWNNRYYSVNKNVTCRNCDKRGHLSKNCPLPQKVRPCCLCSERGHLQYGCP-ARYCLDCSLPMSSTHRC-FERSSWRKRCDRCDMIGHYADACPEIWRQYHLTTKPGPPKKPKTPSGQSALVYCYNCAQKGHYGHECTERRMF--------------------------------------NQAFPTSPFIYCYD---------DKYDIQQRDRRIKRKLKDIKKNGDFP-----------------RQFKRPHGEETD-RYHHDRRK---------SRFSGKRSRWPRE-----------SKETQKE-KTRGREGEKHRRDRQ---PRDEDEDFPRGLKPNSS-SSSNS------QKPSKSLHQASHYHRLREEKLRRE--SMRSKPKKR-KFVEDGSHDDLFLIKQRKKKPKSSGF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AX39-1", "uniprot_id": "ZCHC7_MOUSE", "id": "B1AX39-1", "name": "Zinc finger CCHC domain-containing protein 7", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFGGYETIEAFEDDLYRD--DSSSELSVDSEVEFQLYSQVHYAQSIHNANKEEGYEE----KNCENSETVSSQPNQKNLIVLSDSEVIQLSDTSEVITLSDEDSIYRCKRKNIEVQAEEKTQSPATSHSNK--VAQKCKRNNKKPKPEERPGVIREVMIIEVSSNEEEESTTSENENVESWMLLGSEEDGKDNDILLNLVGCETAGA--EDDVN------WFISDKDIEAKIDNN---------------------------------------------------RSSGRWNNRYYSVNKNVTCRNCDKRGHLSKNCPLPQKVRACCLCSERGHLQYGCP-ARYCLDCSLPMSSNHRC-FERLSWRKRCDRCDMIGHHADACPEIWRQYHLTTKPGPPKKPKTPSGQSALVYCYNCAQKGHYGHECTERRMF--------------------------------------NQTFPTSPFIYCYD---------GKYDIQQRDRRIKRKVKDLKKNGDFP-----------------RQFKRPHVEETDKRRHHDMRK---------SRSPRKYRRWPRE-----------NKETQKE-KTRSREGKTHRRGHQ---PRGEDEDFPRGSKPNAS-GCANN------QKPSKSLHHASHYHRLREERLLRE--SKRSKPKKR-KSTEDGSHDDLFLIKQKKKKPKPSGL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N3Z6-1", "uniprot_id": "ZCHC7_HUMAN", "id": "Q8N3Z6-1", "name": "Zinc finger CCHC domain-containing protein 7", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMFGGYETIEAYEDDLYRD--ESSSELSVDSEVEFQLYSQIHYAQDLDDVIREEEHEE----KNSGNSESSSSKPNQKKLIVLSDSEVIQLSDGSEVITLSDEDSIYRCKGKNVRVQAQENAHGLSSSLQSNELVDKKCKSDIEKPKSEERSGVIREVMIIEVSSSEEEESTISEGDNVESWMLLGCEVDDKDDDILLNLVGCENSVTEGEDGIN------WSISDKDIEAQIANN---------------------------------------------------RTPGRWTQRYYSANKNIICRNCDKRGHLSKNCPLPRKVRRCFLCSRRGHLLYSCP-APLCEYCPVPKMLDHSC-LFRHSWDKQCDRCHMLGHYTDACTEIWRQYHLTTKPGPPKKPKTPSRPSALAYCYHCAQKGHYGHECPEREVY--------------------------------------DPS-PVSPFICYYD---------DKYEIQEREKRLKQKIKVLKKNGVIP-----------------EPSKLPYIKAANENPHHDIRK---------GRASWKSNRWPQE-----------NKETQKEMKNKNRNWEKHRKADR---HREVDEDFPRGPKTYSSPGSFKT------QKPSKPFHRSSHYHTSREDKSPKE--GKRGKQKKKERCWEDDDNDNLFLIKQRKKKS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B5M8-1", "uniprot_id": "A0A8M3B5M8_DANRE", "id": "A0A8M3B5M8-1", "name": "Zinc finger CCHC domain-containing protein 7", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCSPLSNHVCVAPYFCAQAVEITLSLLGFLPRALLEMFSGLQERYDHEDELYRDEEDSSGLSDSDSELEFRLYSQLHYNAEFQENHEESSKVQPLVPQTQLQPETMPPAPPVDVIVIDSGPDSFTVSDST-----EDDESVCANKVQSLKHCKRKSQPSRFRSPSPPQVQAGRSSPDDVVVLDSDLEQSSSESEPPFVEDLDSDTDSDSDSDGLENWMILGKGRQDGDQSIQLNLAQSSFVNTEYVNYRGQEQK--WTVSEKDKQAQIYNKGHGP-----------------------------------------------RHVPNRSTYRYYTEKSITCRNCNKTGHLSKNCPTLKKVPCCSLCGLRGHLLRTCP-NRHCSNCSLPGHTSDDC-LERAFWYKRCHRCGMTGHFIDACPQIWRQYHLTTTAGPIRKSADPKACQKRAYCYNCSRKGHFGHQCSQRRMY--------------------------------------NWSYPSLPVITYYD---------TVNDIKCRDFRLKKKAREMQDAGLISPDGGVVTFTPQPPRKKQKVSHSPHPYSNNTNNHHTPKKRIAHTPKHNPQTNQQNTHWRVKQNSKKPGPHGKNTPQSKEFKSQNKEAKNKKRKKKKAAVIDEDADFPRGSKKSPHKAGFHSSTQKANVKPVKLFGVEKNHMKKKDKSKKKERIQRKRQQKAAKDSAAYPTDENLFQIKQRKVKRSK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVA9-1", "uniprot_id": "Q9VVA9_DROME", "id": "Q9VVA9-1", "name": "Zinc finger CCHC domain-containing protein 7", "aln": "MSDLEEMDSERLNELESILYASIHYSDGFEEHTAMDQPAKESTSDQDARSMPPPPQQKHPIPGQRFVSGTRVINNSMQKPRYWIDGAAAVGEGQVVQAEEQQATTNKTMPAVEESSSSQSMDVDMPQDKSLLLSPEKGTSNQPKTASQPPKHQQIPQAKQQQNIHAKQLQNQQAKPQEQKNSQQKQQQSLKQQNQQSKQHQNQQKKSAPVVQKPKPQPNASTKVNHEAYEAERFDQRLLVAIPPNCPPKKQNKPQQNKQQQQQNKQQQKKQQQSLQHNKQQQQSGPGPFGKANRKLEQIQRLADKKQKSKQAQLNKKQRKQQSPPVEFVNLAETSESSDDDDVVHVPLPPAPIIELDTSDGEQTCTSSQLFHEENAMDATDVKMGLSCITEPEGTSVVASSTTPPMHSPSCSVMSSDDFIVQKDTTRLLTECENANDEDLLVLTETAIREAIGEEPKDKEVVENASEEQEHDHAADTSSEYEFVPPSRLEEIKKNYRVDDQQFRALDVYESESDLTESGIYSKAKSKTTPTIIRNVDSSSGSSSVEEVVEPSVQKTKRLRKRSCSTNNHSQSDPNNDDGLDDSDSDDGVHATGVPGIARGMAVERCKRKIRRISTRHSSDDNSKKAATRIQKPKVAAVHHASSESASEDELPSARDIAERLLNQQQGQGKVQVQKGDGDDDAISIGSDEDSHAEAEFRDAMTDRLAAVFERLDAKAKKMEEDEEQVNASGYISDEEDSRDKSADTTVRSDEDIDASNDLEETNPDKNDRDVTNEEQHVHVEHNLQELRDESLPKSGDLIGWNEEMRSFYNDSWNGENFSVHKVQRMMTGHRHEWRINTADRCPVARPRSHAKCSNCFEMGHVRSKCPRPRKPLVCFICGTMGHAEPRCPNAICFGCGSKQEIYVQQCNKCSFHSRLVCQLCKMRGHGVDHCPDKWRRYHSTTRSNTELDSRVQYRSVQCSYCAGRHSFENCRQRIGDFRSTNYTSQIVSHQKIYKNRGGPIGNLGDLKSFFAIETPFHFKWNNPSMPKNCYYSRFLVNANLAKVQSVKRKSTTAVSQIPEKIYTHEYVPNAQVKAARGEVSTGTAKKPLTKQMPVVESIAENRTAEEPIGKLNREDEKSKDILPLPEVPPEVKQTQDEKLVEGQPNQSQPDEELPMKDDDQEEPSSSVQREEITTNFDNPPTEPGLSR-----TPLAPHELDSDSNYSFSEHFELPSSTTSDGQPNTQLPLVRTMGTLPDVIPLSKDDFELSSNVQGISMCVNSSSTSLRTDETPDPDSSEELPDVPSEGKIIMAREESEYLFSAEGRTFLAAAAKQCHVSVRMDFKDYGYVLVIYGLKKHQEELQVKLLRRSQEVKRKSIEFQSQKPPKRIDVLIRFLRDGINSLNTNLGNAKSHYVRIKELEGMNTKNGFKMAEKKRRQLNMILVGQAGLLNGKTHLDQLLVLLRRLIDDFSPDEHATPQLRNEIEEHWRMIFSSYPHPNYDSLLNSYGRLDQKNRLPSLHIDPVLLGLQQKKTQSQPQSPSKGPPSPTPLPPVRQDMAPPPPPKMSKKKQRQALDQQTQNQQRQQQQQQQRLQQQHQNQQQRLQQQQKQQQQSLQQQHQQQRVQQQRMQQQQQHQQQDNNQYQQNLRRPQIDQMPYNNLQQRSRSDLQLRHTLNPECDRLLSEMDHNQPGSINKDANKPSMFWSRESLKYLDDLFKMTSNTETVERLKRVLQRSQRGLLSHNDYRAVIRLHSLMCN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : . : ::: : . : . * ** : **: .** : .* ** * * * * : *.. ** * :* : . : . . . ..: . . : . . : : ... . . ", "identical_positions": 19, "similar_positions": 43, "identity": "1.09%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030103-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P78562-1", "uniprot_id": "PHEX_HUMAN", "id": "P78562-1", "name": "Phosphate-regulating neutral endopeptidase PHEX", "aln": "--MEAETGSSVETGKKANRGTRIALVVFVGGTLVLGTILFLVSQGLLSLQAKQEYCLKPECIEAAAAILSKVNLSVDPCDNFFRFACDGWISNNPIPEDMPSYGVYPWLRHNVDLKLKELLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLESNIGPEGVWSERKFSLLQTLATFRGQYSNSVFIRLYVSPDDKASNEHILKLDQATLSLAVREDYLDNSTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHENRTSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDISPSENVVVRVPQYFKDLFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLPQWDKCVNFIESALPYVVGKMFVDVYFQEDKKEMMEELVEGVRWAFIDMLEKENEWMDAGTKRKAKEKARAVLAKVGYPEFIMNDTHVNEDLKAIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFDNNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGLEEPLLPGITFTNNQLFFLSYAHVRCNSYRPEAAREQVQIGAHSPPQFRVNGAISNFEEFQKAFNCPPNSTMNRGMDSCRLW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70669-1", "uniprot_id": "PHEX_MOUSE", "id": "P70669-1", "name": "Phosphate-regulating neutral endopeptidase PHEX", "aln": "--MEAETGSTMETGKGTNRGIRIALALFIGGTLVLGTLLFLVSQGLLSFQAKQEYCLKPECIEAAAAIMSKVNLSVDPCENFFRFACDGWISNNPIPEDMPSYGVYPWLRHNVDLKLKALLEKSVSRRRDTEAVQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLEANIGPEGVWSERKFSLLQTLATFRGQYSNSVFIRLYVSPDDKASNEHILKLDQATLSLAVREDFLDNTTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHENRTSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDIGPSENVVVRVPQYFKDLFRILGAERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLPQWDKCVNFIESALPYVVGKMFVNVHFQEDKKEMMEELIEGVRWAFIDMLEKENEWMDAGTKRKAQEKARAVLAKVGYPEFIMNDTYVNEDLKAIKFSESDYFGNVLQTRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFDNNGRKYDKNGNLDPWWSVESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGVEEPLLPGITFTNNQLFFLSYAHVRCNSYRPEAAREQVQIGAHSPPQFRVNGAISNFEEFQKAFNCPRNSTMNRGADSCRLW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1R6K1-1", "uniprot_id": "F1R6K1_DANRE", "id": "F1R6K1-1", "name": "", "aln": "MEMERLGRGGTKASAGPNTLLKAALAVCVCVCIALLIAVITVSQ----KASNEDLCLGPHCVEAAGSILSKMDQSVDPCDDFYQYACGGWLRENPIPEDSSSYGIYPWLRQNVDLKLKELLEQPV-RSGDIEAVKKAKVLYASCMNESALEIEDANPLLKNLKQKEFRWPVLGDALGSSSRWVESQFNLLETLAQIRSQHSKSVLIRLFVAPDDKNSNQYIIKLDQASLSLSSREDYITNTTEAQMYREALLRLMVDVSVMLGASEQAAEAQMKSVLDFEMKLAQIVIPYENRTSENMYNKYSLSKLQRTVPDFNWLGFVRAVIDTELYPDLK-ISSSEQVIVRAPQYFKDLFKLINATDTRTVANYVIWRSVFSRITTLSRRFLYRYLDFARVTTGTTSLTPRWDKCVNYVENTLIYAAGRLFVDKHFQEDKKHMMEELINGIRWAFIDILEKENEWMDEETKRKAIDKAHAVLPKVGYPDFILNDTYINEDIKRLAFTMTDYFGNVMQTLKFIAQSDIGWLRKTVPRTEWFTNPTTVNAFYSSSTNQIRFPAGELQKPFFWGLNYPRSLSYGAIGVIVGHELTHGFDNNGRKYDKDGNLDQWWSNSSINRFTEKTQCMIDQYNSYYWKEAGLNVKGKRTLAENIADNGGIRESFRAYRRWVEKERGGVEEPLLPGVGLTHNQLFFLSYAHVRCNAYRPEAARDQIQSGAHSPPKYRVIGAMSNFEEFRKAFNCPETSIMNRGAESCRVW", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** . ::. .* : **.: : :.* :: *** :::: ** *.*:***.:*:**:: *****::*:::**.**: :****** .***:*****:******* ***:.: * * **::***:**:*****.*:* **:***: *::. ****** :*... * * :*.**:*** :*.*:*:**:***:*:**** **::*:*****:***: ***:: *:***: **:** ::***.:*:***... ** :***** :*:*:*:*:**:****** **** .:*:*. :*:*:***::: ****.***.** *..**:*:**.********:::.: .:*:***::** *:***..***** **:*:*:** ***:* *:******::*.:* *..*::**: :******.*****::*:******:********* ***** :**:***.*****:**:***::***:* : *: :******:** *::****: ****:**:***************:******************* :*****************:*************:**** *** .* ::*.***:***:**..****:***********.********:**:*****:*::..* *:*******: :*:**************:*******:*:* ******::** **:******:****** .* **** :***:*", "identical_positions": 470, "similar_positions": 190, "identity": "62.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030109-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y230-1", "uniprot_id": "RUVB2_HUMAN", "id": "Q9Y230-1", "name": "RuvB-like 2", "aln": "MATVTATTKVPEIRDVTRIERIGAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVLEMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALTQAFRRSIGVRIKEETEIIEGEVVEIQIDRPATGTGSKVGKLTLKTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSPHGIPIDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDAFLFNELKGET-MDTS---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WTM5-1", "uniprot_id": "RUVB2_MOUSE", "id": "Q9WTM5-1", "name": "RuvB-like 2", "aln": "MATVAATTKVPEIRDVTRIERIGAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVLEMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALTQAFRRSIGVRIKEETEIIEGEVVEIQIDRPATGTGSKVGKLTLKTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSPHGIPIDLLDRLLIVSTSPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDAFLFNELKGET-MDTS---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AAZ0-1", "uniprot_id": "A0A8I6AAZ0_RAT", "id": "A0A8I6AAZ0-1", "name": "RuvB-like helicase", "aln": "---CEAGRPAPRTPAVQEATPTCAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVLEMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALTQAFRRSIGVRIKEETEIIEGEVVEIQIDRPATGTGSKVGKLTLKTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSPHGIPIDLLDRLLIVSTSPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDAFLFNELRKET-MGSTPGGQPGRRTEAKRSSR-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P83571-1", "uniprot_id": "RUVB2_DANRE", "id": "P83571-1", "name": "RuvB-like 2", "aln": "MAAQVATTKVPEVRDITRIERIGAHSHIRGLGLDDALEPRQVSQGMVGQLASRRAAGLILEMIKDGQIAGRAVLIAGQPGTGKTAIAMGIAQSLGPDTPFTALAGSEIFSLEMSKTEALSQAFRKAIGVRIKEETEIIEGEVVEIQIDRPATGTGAKVGKLTLKTTEMETIYDLGTKMIESLSKERVQAGDVITIDKATGKISKLGRSFTRARDYDAMGAQTQFVQCPEGELQKRKEVVHTVSLHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVSEWREEGKAEIIPGVLFIDEVHMLDIECFSFLNRALESDLSPVLIMATNRGITRIRGTNYQSPHGIPIDMLDRLLIIATTPYTEKETRQILKIRCEEEDVELSEEAHTVLTRIGQETSLRYAIQLISTAGLVCRKRRGTEVQVEDIKRVYSLFLDEARSSQYMKEYQDSFLFNETQTSQ-MDTS---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3K3-1", "uniprot_id": "RUVB2_DROME", "id": "Q9V3K3-1", "name": "RuvB-like helicase 2", "aln": "----MAETEKIEVRDVTRIERIGAHSHIRGLGLDDVLEARLVSQGMVGQKDARRAAGVVVQMVREGKIAGRCILLAGEPSTGKTAIAVGMAQALGTETPFTSMSGSEIYSLEMSKTEALSQALRKSIGVRIKEETEIIEGEVVEIQIERPASGTGQKVGKVTLKTTEMETNYDLGNKIIECFMKEKIQAGDVITIDKASGKVNKLGRSFTRARDYDATGAQTRFVQCPEGELQKRKEVVHTVTLHEIDVINSRTHGFLALFSGDTGEIKQEVRDQINNKVLEWREEGKAEINPGVLFIDEVHMLDIECFSFLNRALESDMAPVVVMATNRGITRIRGTNYRSPHGIPIDLLDRMIIIRTVPYSEKEVKEILKIRCEEEDCIMHPDALTILTRIATDTSLRYAIQLITTANLVCRRRKATEVNTEDVKKVYSLFLDENRSSKILKEYQDDYMFSEITEEVERDPAAGGGAKRRVEGGGGDAQPMEH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12464-1", "uniprot_id": "RUVB2_YEAST", "id": "Q12464-1", "name": "RuvB-like protein 2", "aln": "--MSIQTSDPNETSDLKSLSLIAAHSHITGLGLDENLQPRPTSEGMVGQLQARRAAGVILKMVQNGTIAGRAVLVAGPPSTGKTALAMGVSQSLGKDVPFTAIAGSEIFSLELSKTEALTQAFRKSIGIKIKEETELIEGEVVEIQIDRSITG-GHKQGKLTIKTTDMETIYELGNKMIDGLTKEKVLAGDVISIDKASGKITKLGRSFARSRDYDAMGADTRFVQCPEGELQKRKTVVHTVSLHEIDVINSRTQGFLALFTGDTGEIRSEVRDQINTKVAEWKEEGKAEIVPGVLFIDEVHMLDIECFSFINRALEDEFAPIVMMATNRGVSKTRGTNYKSPHGLPLDLLDRSIIITTKSYNEQEIKTILSIRAQEEEVELSSDALDLLTKTGVETSLRYSSNLISVAQQIAMKRKNNTVEVEDVKRAYLLFLDSARSVKYVQENESQYIDDQGNVQISIAKSADPDAMDTTE-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ***** *****: *:.* .*:***** :*****::::*:::* ****.:*:** *.*****:*:*::*:** :.***:::****:***:******:**:*::**::******:**********:*. :* * * **:*:***:*** *:**.*:*: : *::: *****:****:**:.******:*:***** *::*:*****:******* *****:***********:******:******:.***:*** ** **:******* ***************.***:*****.:::*:::******::: ***.*:****:*:*:*** :*: * .*.*:: : ** **.:**: : :* :**: . :*****: :**:.* :. :*: . *:.:*:*:.* ****. ** : ::* :. :: .: . : ", "identical_positions": 257, "similar_positions": 129, "identity": "52.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030109-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60122-1", "uniprot_id": "RUVB1_MOUSE", "id": "P60122-1", "name": "RuvB-like 1", "aln": "-MKIEEVKS--------TTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESLQKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGVAELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIPLDLLDRVMIIRTMLYTPQEMKQIIKIRAQ-TEGINISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILADQQDKYMK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P60123-1", "uniprot_id": "RUVB1_RAT", "id": "P60123-1", "name": "RuvB-like 1", "aln": "-MKIEEVKS--------TTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESLQKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGVAELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIPLDLLDRVMIIRTMLYTPQEMKQIIKIRAQ-TEGINISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILADQQDKYMK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y265-1", "uniprot_id": "RUVB1_HUMAN", "id": "Q9Y265-1", "name": "RuvB-like 1", "aln": "-MKIEEVKS--------TTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESLQKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGIAELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIPLDLLDRVMIIRTMLYTPQEMKQIIKIRAQ-TEGINISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILADQQDKYMK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2K0H9-1", "uniprot_id": "A0A0G2K0H9_RAT", "id": "A0A0G2K0H9-1", "name": "RuvB-like helicase", "aln": "-MKIEEVKS--------TTKTQRIASHSHVKGLGLDESGLAKQAASGLIGQENAREACGVIVELIKSKKMAGRAVLLAGPPETGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESLQKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEKYVPLPNGDVHKKKEIIQDVTLQYLDVANVRPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGVAELVPGVLFVDE-----------------SSITPIVIFASNGANCVIRGTENITSPHGIPLDLLDRVIIIRTMLYTPQEMKQIIKIRAQGMEGINISEEALNHLGEIGTKTMLRFSVQLLTPANLLAKINRKDSIEKEHVEEISELFYDAKSSAKILADQQDKYMK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8AWW7-1", "uniprot_id": "RUVB1_DANRE", "id": "Q8AWW7-1", "name": "RuvB-like 1", "aln": "-MKIEEVKS--------TTKTQRIASHSHVKGLGLDEAGNAKQSASGLVGQESAREACGIITELIRSKKMAGRAILLAGPPGTGKTALALAMAQELGNKVPFCPMVGSEVYSSEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIYESLQKERVEVGDVIYIEANSGAVKRQGRCDTFATEFDLEAEEYVPLPKGDVHEKKEIIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGVAELVPGVLFIDEVHMLDIECFTYLHRALESSIAPIVVFASNRGNCLIRGTEDISSPHGIPLDLLDRVMIIRTMLYTPQEMKQIIKIRAQ-TEGLNISEEALSHLGEIGTKTTLRYAVQLLTPASLLARVQGREVVEKEHVEEINELFYDAKSSAKILQDQHTKFMK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VH07-1", "uniprot_id": "RUVB1_DROME", "id": "Q9VH07-1", "name": "RuvB-like helicase 1", "aln": "-MKIEEVKS--------TVRTQRIAAHSHVKGLGLDEVGAAVHSAAGLVGQKAAREAAGIVVDLIKSKKMAGRALLLAGPPGTGKTAIALAIAQELGNKVPFCPMVGSEVFSNEIKKTEVLMENFRRSIGLRIRETKEVYEGEVTELTPVETENPMGGYGKTISNVVIGLKTAKGTKQLKLDPSIFDALQKEKVEVGDVIYIEANSGAVKRQGRSDTFATEFDLETEEYVPLPKGDVHKKKEVIQDVTLHDLDVANARPQGGQDVLSMMGQLMKPKKTEITDKLRMEINKVVNKYIDQGIAELVPGVLFIDEIHMLDLETFTYLHKSLESPIAPIVIFATNRGRCVIRGTTDIVSPHGIPLDLLDRLLIIRTLLYSTADMEQIIKLRAQ-TEGLQLEENAFTRLSEIGTSSTLRYAVQLLTPAHQMCKVNGRNQISKDDIEDVHSLFLDAKRSSKHLSEKNNKFML", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03940-1", "uniprot_id": "RUVB1_YEAST", "id": "Q03940-1", "name": "RuvB-like protein 1", "aln": "MVAISEVKENPGVNSSNSGAVTRTAAHTHIKGLGLDESGVAKRVEGGFVGQIEAREACGVIVDLIKAKKMSGRAILLAGGPSTGKTALALAISQELGPKVPFCPLVGSELYSVEVKKTETLMENFRRAIGLRIKETKEVYEGEVTELTPEDAENPLGGYGKTISHVIVGLKSAKGTKTLRLDPTIYESIQREKVSIGDVIYIEANTGAVKRVGRSDAYATEFDLETEEYVPLPKGEVHKKKEIVQDVTLHDLDVANARPQGGQDVISMMGQLLKPKKTEITEKLRQEVNKVVAKYIDQGVAELIPGVLFIDEVNMLDIEIFTYLNKALESNIAPVVVLASNRGMTTVRGTEDVISPHGVPPDLIDRLLIVRTLPYDKDEIRTIIERRAT-VERLQVESSALDLLATMGTETSLRYALQLLAPCGILAQTSNRKEIVVNDVNEAKLLFLDAKRSTKILETSAN-YL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.***. : . * *:*:*:******* * * : .*::** ****.*::.:**::***:***:**** * *****:***::**** ******:****::* *:****.*******:*****:*************** ::***:********:*::***:***** *:***:*::::*:*:*. *********:***** **.*::*******:*:*****:*:**:***::*****: *****.*******::******:********:*** *:**** ******:***:*****:** * *:*:*::*:* . :*** :: ****:* **:**::*:**: * ::. **: ** * :::...*: *. :**.: **:::***:*. :.: . :. : :.::: ** *** *:* * . :: ", "identical_positions": 257, "similar_positions": 119, "identity": "55.15%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030113-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96L46-1", "uniprot_id": "CPNS2_HUMAN", "id": "Q96L46-1", "name": "Calpain small subunit 2", "aln": "MFLAKALLEGADRG----------LGEALGGLFG--GGGQRREGGGR--NIGG----------IVGGIVNFISEAAAAQYTP-EPPPTQQHFTSVEASESEEVRRFRQQFTQLAGPDMEVGATDLMNILNKVLSKHKDLKTDGFSLDTCRSIVSVMDSDTTGKLGFEEFKYLWNNIKKWQCVYKQYDRDHSGSLGSSQLRGALQAAGFQLNEQLYQMIVRRYANEDGDMDFNNFISCLVRLDAMFRAFKSLDRDRDGLIQVSIKEWLQLTMYS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D7J7-1", "uniprot_id": "CPNS2_MOUSE", "id": "Q9D7J7-1", "name": "Calpain small subunit 2", "aln": "MFLAKAILEGADRG----------LGGALGGLLG--GGGQARAGGG---NIGG----------ILGGIVNFISEAAAAQYTP-EPPPQQQHFTVVEASESEEVRRFRQQFTQLAGPDMEVGATDLMNILNKVLSKHKELKTEGFSLDTCRSIVSVMDSDTTGKLGFEEFKYLWNNIKKWQCVFKQYDSDHSGSLGSSQLHGAMQAAGFQLNEQLYLMIVRRYADEDGGMDFNNFISCLVRLDAMFRAFKALDRDRDGLIQVSIREWLQLTMYS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64537-1", "uniprot_id": "CPNS1_RAT", "id": "Q64537-1", "name": "Calpain small subunit 1", "aln": "MFLVNSFLKGGGGGGGGGG-LGGGLGNVLGGLISGAAGGGGGGGGGGGMGLGGGGGGGGTAMRILGGVISAISEAAA-QYNP-EPPPPRSHYSNIEANESEEERQFRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQGIYKRFDTDRSGTIGSNELPGAFEAAGFHLNQHIYSMIIRRYSDETGNMDFDNFISCLVRLDAMFRAFRSLDKNGTGQIQVNIQEWLQLTMYS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88456-1", "uniprot_id": "CPNS1_MOUSE", "id": "O88456-1", "name": "Calpain small subunit 1", "aln": "MFLVNSFLKGGGGGGGGGG-LGGGLGNVLGGLISGAAGGGGGGGGG--MGLGGGGGGGGTAMRILGGVISAISEAAA-QYNP-EPPPPRSHYSNIEANESEEVRQFRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQAIYKRFDTDRSGTIGSHELPGAFEAAGFHLNEHLYSMIIRRYADESGNMDFDNFISCLVRLDAMFRAFKSLDKNGTGQIQVNIQEWLQLTMYS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04632-1", "uniprot_id": "CPNS1_HUMAN", "id": "P04632-1", "name": "Calpain small subunit 1", "aln": "MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGG---GGGGGGGGGGTAMRILGGVISAISEAAA-QYNP-EPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LYC9-1", "uniprot_id": "Q1LYC9_DANRE", "id": "Q1LYC9-1", "name": "", "aln": "MFLLK---------------------KAIG------------------------------------GVIDVIGNIDPNQFVPSEPPPPRRPLAYAVSNESAEEQQFRKVFNQLAGDDMEVSPTELMNILNKIISKHGDLKTDGFTIESCRSMVAVMDSDSTGKLGFHEFKHLWNNIKKWQGIYKTYDRDHSGTIGADELPAAFRAAGFPLTDQLFQMIIRRYSDESGNMDFDNYIGCLVRLDAMCHAFKTLDKDNDGTIKVNVQEWLQLTMYS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** : .:* *::. *.: . *: * **** : : :.** * ::**: * **** ****..*:*******::::* :***:** :::***:*:*****:******.***:******:** ::* :* *:**:: : :* .*:.**** *.:::: **:***::* *.***:*:*.******** :**::**:: * *:*.::*********", "identical_positions": 114, "similar_positions": 67, "identity": "41.76%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030114-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920L5-1", "uniprot_id": "ELOV6_MOUSE", "id": "Q920L5-1", "name": "Very long chain fatty acid elongase 6", "aln": "------------------------------------------MNMSVLTLQEY----EFEKQFNENEAIQWMQENWKKSFLFSALYAAFIFGGRHLMNKR--AKFELRKPLVLWSLTLAVFSIFGALRTGAYMLYILMTKGLKQSVCDQSFYN-GPVSKFWAYAFVLSKAPELGDTIFIILRKQKLIFLHWYHHITVLLYSWYSYKDMVAGGGWFMTMNYGVHAVMYSYYALRAAGFRVSRKFAMFITLSQITQMLMGCVINYLVFN------WMQ----HDNDQCYSHFQNIFWSSLMYLSYLVLFCHFFFEAYIG----KVK--KATKAE------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q920L6-1", "uniprot_id": "ELOV6_RAT", "id": "Q920L6-1", "name": "Very long chain fatty acid elongase 6", "aln": "------------------------------------------MNMSVLTLQEY----EFEKQFNENEAIQWMQENWKKSFLFSALYAAFIFGGRHLMNKR--AKFELRKPLVLWSLTLAVFSIFGALRTGAYMLYILMTKGLKQSVCDQSFYN-GPVSKFWAYAFVLSKAPELGDTIFIILRKQKLIFLHWYHHITVLLYSWYSYKDMVAGGGWFMTMNYGVHAVMYSYYALRAAGFRVSRKFAMFITLSQITQMLMGCVINYLVFN------WMQ----HDNDQCYSHFQNIFWSSLMYLSYLLLFCHFFFEAYIG----KVK--KATKAE------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H5J4-1", "uniprot_id": "ELOV6_HUMAN", "id": "Q9H5J4-1", "name": "Very long chain fatty acid elongase 6", "aln": "------------------------------------------MNMSVLTLQEY----EFEKQFNENEAIQWMQENWKKSFLFSALYAAFIFGGRHLMNKR--AKFELRKPLVLWSLTLAVFSIFGALRTGAYMVYILMTKGLKQSVCDQGFYN-GPVSKFWAYAFVLSKAPELGDTIFIILRKQKLIFLHWYHHITVLLYSWYSYKDMVAGGGWFMTMNYGVHAVMYSYYALRAAGFRVSRKFAMFITLSQITQMLMGCVVNYLVFC------WMQ----HD--QCHSHFQNIFWSSLMYLSYLVLFCHFFFEAYIG----KMR--KTTKAE------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PC64-1", "uniprot_id": "ELOV6_DANRE", "id": "Q6PC64-1", "name": "Very long chain fatty acid elongase 6", "aln": "--------------------------------------------MSVLALQEY----EFERQFNEDEAIRWMQENWKKSFLFSALYAACILGGRHVMKQR--EKFELRKPLVLWSLTLAAFSIFGAIRTGGYMVNILMTKGLKQSVCDQSFYN-GPVSKFWAYAFVLSKAPELGDTLFIVLRKQKLIFLHWYHHITVLLYSWYSYKDMVAGGGWFMTMNYLVHAVMYSYYALRAAGFKISRKFAMFITLTQITQMVMGCVVNYLVYL------WMQ----QGQ-ECPSHVQNIVWSSLMYLSYFVLFCQFFFEAYIT----KRKSNAAKKSQ------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VV87-1", "uniprot_id": "ELOV6_DROME", "id": "Q9VV87-1", "name": "Very long chain fatty acid elongase 6", "aln": "-----------------------------------------MINMDISVTPNYSYIFDFENDFIHQRTRKWMLENWTWVFYYCGIYMLVIFGGQHFMQNR--PRFQLRGPLIIWNTLLAMFSIMGAARTAPELIHVLRHYGLFHSVCVPSYIEQDRVCGFWTWLFVLSKLPELGDTIFIVLRKQPLIFLHWYHHITVLIYSWFSYTEYTSSARWFIVMNYCVHSVMYSYYALKAARFNPPRFISMIITSLQLAQMIIGCAINVWANG------FLKT---HGTSSCHISQRNINLSIAMYSSYFVLFARFFYKAYLAPGGHKSRRMAASLAAQNVVKQSSSPQQASESSKFIGAGEDQAAYLRKAKAQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25358-1", "uniprot_id": "ELO2_YEAST", "id": "P25358-1", "name": "Fatty acid elongase 2", "aln": "MNSLVTQYAAPLFERYPQLHD--------YLPTLERPFFNISLWEHFDDVVTRVTNGRFVPSEFQFIAGELPLSTLPPVLYAITAYYVIIFGGRFLLSKS--KPFKLNGLFQLHNLVLTSLSLTLLLLMVEQLVPIIVQHGLYFAICNIGAWT--QPLVTLYYMNYIVKFIEFIDTFFLVLKHKKLTFLHTYHHGATALLCYTQLMGTTSISWVPISLNLGVHVVMYWYYFLAARGIR--VWWKEWVTRFQIIQFVLDIGFIYFAVYQKAVHLYFP--ILPHCGDCVGSTTATFAGCAIISSYLVLFISFYINVYKRKG--TKTSRVVKRAHGGVAAKVNEYVNVDLKNVPTPSPSPKPQHRRKR---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39540-1", "uniprot_id": "ELO1_YEAST", "id": "P39540-1", "name": "Fatty acid elongase 1", "aln": "---MVSDWKNFCLEKASRFR-----------PTIDRPFFNIYLWDYFNRAVGWATAGRFQPKDFEFTVGKQPLSEPRPVLLFIAMYYVVIFGGRSLVKSC--KPLKLRFISQVHNLMLTSVSFLWLILMVEQMLPIVYRHGLYFAVCNVESWT--QPMETLYYLNYMTKFVEFADTVLMVLKHRKLTFLHTYHHGATALLCYNQLVGYTAVTWVPVTLNLAVHVLMYWYYFLSASGIR--VWWKAWVTRLQIVQFMLDLIVVYYVLYQKIVAAYFKNACTPQCEDCLGSMTAIAAGAAILTSYLFLFISFYIEVYKRGS--ASGKKKINKNN------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40319-1", "uniprot_id": "ELO3_YEAST", "id": "P40319-1", "name": "Fatty acid elongase 3", "aln": "MNTTTSTVIAAVADQFQSLNSSSSCFLKVHVPSIENPFG-IELWPIFSKVFEYFSG--YPAEQFEFIHNKTFLANGYHAVSIIIVYYIIIFGGQAILRALNASPLKFKLLFEIHNLFLTSISLVLWLLMLEQLVPMVYHNGLFWSICSKEAFA--PKLVTLYYLNYLTKFVELIDTVFLVLRRKKLLFLHTYHHGATALLCYTQLIGRTSVEWVVILLNLGVHVIMYWYYFLSSCGIR--VWWKQWVTRFQIIQFLIDLVFVYFATYTFYAHKYLDG-ILPNKGTCYGTQAAAAYGYLILTSYLLLFISFYIQSYKKGG--KKTVKKESEVSGSVASGSSTGVKTSNTKVSSRKA-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . . . * *:**: .: :::. : . *: .*: :: :: ** ::* : : * *: **.:::*::: * *** *** :. : .: . .: : :* ** :** ** * : :. :* *: *:::. . . :: * . : **:.** *: : * . ", "identical_positions": 39, "similar_positions": 66, "identity": "10.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030114-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AIH6-1", "uniprot_id": "A0A8I6AIH6_RAT", "id": "A0A8I6AIH6-1", "name": "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "aln": "MASAVAIAAQAGKLLRERSLRPRLLAVRSQAGHLTPRRWLNLQEYQSKKLMSEHGVRVQRFFVASTAKEAQEAAKRLNAKEIVLKAQILAGGRGKGVFDSGLKGGVHLTKDPKVVGQLAQQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRSHNGPVLVGSPQGGVDIEEVAASSPELIFKEQIDIFEGIKDSQAQRMAENLGFLGSLKNQAADQIKKLYHLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSE-NEPIENEAARYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKESQVYQAFKLLTSDPKVEAILVNIFGGIVNCAIIANGITKACQELELKVPLVVRLEVVLGAQAASLKTQTLMESHCLCPEVQVRTQGKPKATTHHRVP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2I8-1", "uniprot_id": "SUCB2_MOUSE", "id": "Q9Z2I8-1", "name": "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "aln": "MASPVAIAAQAGKLLRERALRP-LLAVRSQAGHLTPRRWLNLQEYQSKKLMSEHGVRVQRFFVANTAKEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGLKGGVHLTKDPKVVGELAQQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRSHNGPVIVGSPQGGVDIEEVAASSPELIFKEQIDIFEGIKDSQAQRMAENLGFLGSLKNQAADQITKLYHLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSE-NEPIENEAARYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKEAQVYEAFKLLTSDPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTNVQEAQNILKSSGLP---ITSAVDLEDAAKKAVASVAKK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96I99-1", "uniprot_id": "SUCB2_HUMAN", "id": "Q96I99-1", "name": "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "aln": "MAS--PVAAQAGKLLRALALRPRFLAAGSQAVQLTSRRWLNLQEYQSKKLMSDNGVRVQRFFVADTANEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGLKGGVHLTKDPNVVGQLAKQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRSCNGPVLVGSPQGGVDIEEVAASNPELIFKEQIDIFEGIKDSQAQRMAENLGFVGPLKSQAADQITKLYNLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSE-NEPIENEAAKYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKEAQVYQAFKLLTADPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTNVQEAQKILNNSGLP---ITSAIDLEDAAKKAVASVAKK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R7X5-1", "uniprot_id": "F1R7X5_DANRE", "id": "F1R7X5-1", "name": "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "aln": "MAASVACQAAARGLRS--ASTKQLLVCRNQLTRVSPRRWLNLQEYQSKKLMQDSGVAVQRFFVADTASEALEAAKRLKAKEIVLKAQILAGGRGKGVFNSGLKGGVHLTKDPAVVGELASKMLGYNLTTKQTPKEGVEVKTVMVAEALDISRETYFAILMDRSCNGPVMVGSPQGGMDIEEVAAATPELIFKEVIDIFEGVRDDQALRMAANLGFKGPLERQAADQIKRLYDLFLKVDATQVEVNPLGETPEGQVVCFDAKINFDDNAEFRQKAVFSMDDTAE-SDPIETEAAKYDLKYIGMDGNIACFVNGAGLAMATCDIIDLHGGKPANFLDLGGGVKENQVYAAFKLLTADPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTNVHEAKRILSESGLP---ITSATDLDDAARKAVAAIAKK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V470-1", "uniprot_id": "Q9V470_DROME", "id": "Q9V470-1", "name": "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "aln": "-----------------MSFLLKAVTTARHIVHKVPVRNLNLLEFQSKDLLQKYGVAIQQFKVLNNSKADAEVVKTFECPEYVVKAQILAGGRGKGTFDNGFKGGVHITTNKSEVLSLTQQMIGNRLITKQTPKSGILVNKVMVARSINITRETYLCILLDREHNGPVLIASPAGGMDIEAVAEETPEKIKTVPLDIGKPIPESTLLEVAKFLEFKGDSVKRCAEEIQKLYTLFKAVDAVQIEINPLAETDKGEVISVDAKLNFDDNAQFRQKDIFSMDVTEEESDPREVEAAKYNLNYVAMDGNIGCLVNGAGLAMATMDIIKLNGGEPANFLDVGGGVREDQVAKAFEILTADPKVKGILVNVFGGIVNCATIANGIVAASKKLQLNVPLVVRLEGTNVNQAREILKNSGLP---IQTASDLDDAAHKAVAALN---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. : : . * *** *:***.*:.. ** :*:* * ..:. *..* ::. * *:************.*:.*:*****:*.: * .*:.:*:* .* ******.*: *:.****.:::*:****:.**:**. ****::.** **:*** ** .** * . :** : : :. .:* * * * :.*::* :** ** :**.*:*:**:.** :*:*:..***:******:**** :*:** . * .:* * ***:*:*:*:.:****.*:********** *** *:**:******:****:* ** **::**:****:.****:******** *****. *.::*:*:******** . :* : ..: : : . :: .: .:: ", "identical_positions": 198, "similar_positions": 125, "identity": "45.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030114-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24547-1", "uniprot_id": "IMDH2_MOUSE", "id": "P24547-1", "name": "Inosine-5'-monophosphate dehydrogenase 2", "aln": "--------MADYLISGGTSYVP--------------DDGLTAQQLFNCGD--GLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAPAGVTLKEANEILQRSKKGKLPIVNENDELVAIIARTDLKKNRDYPLASKDA-KKQLLCGAAIGTHEDDKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYIKEKYPSLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDK----HLSSQNRYFS-EADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PU28-1", "uniprot_id": "IMDH2_RAT", "id": "E9PU28-1", "name": "Inosine-5'-monophosphate dehydrogenase 2", "aln": "--------MADYLISGGTSYVP--------------DDGLTAQQLFNCGD--GLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAPAGVTLKEANEILQRSKKGKLPIVNESDELVAIIARTDLKKNRDYPLASKDT-KKQLLCGAAIGTHEDDKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYIKEKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDK----HLSSQNRYFS-EADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHGLHSYEKRLF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12268-1", "uniprot_id": "IMDH2_HUMAN", "id": "P12268-1", "name": "Inosine-5'-monophosphate dehydrogenase 2", "aln": "--------MADYLISGGTSYVP--------------DDGLTAQQLFNCGD--GLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDA-KKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDK----HLSSQNRYFS-EADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0UXP9-1", "uniprot_id": "IMDH2_DANRE", "id": "B0UXP9-1", "name": "Inosine-5'-monophosphate dehydrogenase 2", "aln": "--------MADYLISGQTGYVP--------------DDGLTGQQLFNSGD--GLTYNDFLILPGYIDFTADQVDLTSALTKQITMKTPLISSPMDTVTESGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKRYEQGFITDPVVMSPNERVRDVFQAKARHGFCGIPITDNGQMGGRLVGIISSRDIDFLKESEHDLPLSEVMTKREDLVVAPAGVTLKEANEILQRSKKGKLPIVNEEGCLVAIIARTDLKKNRDFPLASKDS-RKQLLCGAAIGTHNDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKEKYPNVQVIGGNVVTAAQAKNLIDAGADALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQTVGHIAKALALGASTVMMGSLLAATSEAPGEYFFSDGIRLKKYRGMGSLDAMDK----NLGSQTRYFS-ESDKIKVAQGVSGAVQDKGSIHKFVPYLLVGIQHSCQDIGAKSLTQLRAMMYSGELRFEKRTMSAQMEGGVHSLHSYEKRLF-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q07152-1", "uniprot_id": "IMDH_DROME", "id": "Q07152-1", "name": "Inosine-5'-monophosphate dehydrogenase", "aln": "MESTTKVKVNGFVESTSSSAAPAIQTKSTTGFDAELQDGLSCKELFQNGE--GLTYNDFLILPGYIDFTAEEVDLSSPLTKSLTLRAPLVSSPMDTVTESEMAIAMALCGGIGIIHHNCTPEYQALEVHKVKKYKHGFMRDPSVMSPTNTVGDVLEARRKNGFTGYPVTENGKLGGKLLGMVTSRDIDFR-ENQPEVLLADIMTT--ELVTAPNGINLPTANAILEKSKKGKLPIVNQAGELVAMIARTDLKKARSYPNASKDS-NKQLLVGAAIGTRSEDKARLALLVANGVDVIILDSSQGNSVYQVEMIKYIKETYPELQVIGGNVVTRAQAKNLIDAGVDGLRVGMGSGSICITQEVMACGCPQATAVYQVSTYARQFGVPVIADGGIQSIGHIVKAIALGASAVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMERG-DAKGAAMSRYYHNEMDKMKVAQGVSGSIVDKGSVLRYLPYLECGLQHSCQDIGANSINKLRDMIYNGQLRFMKRTHSAQLEGNVHGLFSYEKRLF-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50095-1", "uniprot_id": "IMDH3_YEAST", "id": "P50095-1", "name": "Inosine-5'-monophosphate dehydrogenase 3", "aln": "-----MAAVRDYKTALEFAKSLP------------RLDGLSVQELMDSKTRGGLTYNDFLVLPGLVDFPSSEVSLQTKLTRNITLNTPFVSSPMDTVTESEMAIFMALLGGIGFIHHNCTPEDQADMVRRVKNYENGFINNPIVISPTTTVGEAKSMKERFGFSGFPVTEDGKRNGKLMGIVTSRDIQFVEDNS--LLVQDVMTK--NPVTGAQGITLSEGNEILKKIKKGKLLIVDDNGNLVSMLSRTDLMKNQNYPLASKSATTKQLLCGAAIGTIDADKERLRLLVEAGLDVVILDSSQGNSIFQLNMIKWIKETFPDLEIIAGNVATREQAANLIAAGADGLRIGMGSGSICITQEVMACGRPQGTAVYNVCEFANQFGIPCMADGGVQNIGHITKALALGSSTVMMGGMLAGTTESPGEYFYQDGKRLKAYRGMGSIDAMQKTGTKGNASTSRYFS-ESDSVLVAQGVSGAVVDKGSIKKFIPYLYNGLQHSCQDIGYKSLTLLKENVQSGKVRFEFRTASAQLEGGVHNLHSYEKRLHN", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38697-1", "uniprot_id": "IMDH2_YEAST", "id": "P38697-1", "name": "Inosine-5'-monophosphate dehydrogenase 2", "aln": "-----MAAIRDYKTALDFTKSLP------------RPDGLSVQELMDSKIRGGLTYNDFLILPGLVDFASSEVSLQTKLTRNITLNIPLVSSPMDTVTESEMATFMALLGGIGFIHHNCTPEDQADMVRRVKNYENGFINNPIVISPTTTVGEAKSMKEKYGFAGFPVTTDGKRNAKLVGVITSRDIQFVEDNS--LLVQDVMTK--NPVTGAQGITLSEGNEILKKIKKGRLLVVDEKGNLVSMLSRTDLMKNQNYPLASKSANTKQLLCGASIGTMDADKERLRLLVKAGLDVVILDSSQGNSIFELNMLKWVKESFPGLEVIAGNVVTREQAANLIAAGADGLRIGMGTGSICITQEVMACGRPQGTAVYNVCEFANQFGVPCMADGGVQNIGHITKALALGSSTVMMGGMLAGTTESPGEYFYQDGKRLKAYRGMGSIDAMQKTGTKGNASTSRYFS-ESDSVLVAQGVSGAVVDKGSIKKFIPYLYNGLQHSCQDIGCRSLTLLKNNVQRGKVRFEFRTASAQLEGGVHNLHSYEKRLHN", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P50094-1", "uniprot_id": "IMDH4_YEAST", "id": "P50094-1", "name": "Inosine-5'-monophosphate dehydrogenase 4", "aln": "----MSAAPLDYKKALEHLKTYS------------SKDGLSVQELMDSTTRGGLTYNDFLVLPGLVNFPSSAVSLQTKLTKKITLNTPFVSSPMDTVTEADMAIYMALLGGIGFIHHNCTPKEQASMVKKVKMFENGFINSPIVISPTTTVGEVKVMKRKFGFSGFPVTEDGKCPGKLVGLVTSRDIQFLEDDS--LVVSEVMTK--NPVTGIKGITLKEGNEILKQTKKGKLLIVDDNGNLVSMLSRADLMKNQNYPLASKSATTKQLLCGAAIGTIEADKERLRLLVEAGLDVVILDSSQGNSVFQLNMIKWIKETFPDLEIIAGNVATREQAANLIAAGADGLRIGMGSGSICITQEVMACGRPQGTAVYNVCQFANQFGVPCMADGGVQNIGHITKALALGSSTVMMGGMLAGTTESPGEYFYKDGKRLKAYRGMGSIDAMQKTGNKGNASTSRYFS-ESDSVLVAQGVSGAVVDKGSIKKFIPYLYNGLQHSCQDIGCESLTSLKENVQNGEVRFEFRTASAQLEGGVHNLHSYEKRLYN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : ***: ::*:: ********:*** ::*.:. *.* : **:.:*:. *::*********: ** *** ****:*******: ** *::** :::**: .* *:**. * :. : : ** * *:* *: .:*:*:::****:* :.. : ::**. : *.. *:.* .* **:: ***:* :*:: . **::::*:** * :.:* ***.: **** **:*** . ** ** **. *:**::********:::::*:*::*:.:* :::*.***.* ** *** **.*.**:***:*********:*** **.****:*. :*.:**:* :****:*.:***.**:***:*:****.:**.*:*:*****:.** *** ******::**:: .: .**: * *.: *******:: ****: :::*** *:******** .*:. :: : *:::* ** ***:**.**.*.******. ", "identical_positions": 252, "similar_positions": 158, "identity": "46.24%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030114-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ULV4-1", "uniprot_id": "COR1C_HUMAN", "id": "Q9ULV4-1", "name": "Coronin-1C", "aln": "-MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLT---------EPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADG-NVFTTGFSRMSERQLALWNPKNMQEP--IALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHER-KCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNAD-PILISLKH-------GYIPG--------KNRDLKVVKK-NILDSKPTANKKCDLISIPKKTTDTAS--------------------VQNEAKLDEIL--------------------------------------------KEIKSIKDTICNQDERISKLEQQMAKIAA---------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3V624-1", "uniprot_id": "G3V624_RAT", "id": "G3V624-1", "name": "Coronin", "aln": "-MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLT---------EPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVRVIDPRRQEIVAEKEKAHEGARPMRAIFLADG-NVFTTGFSRMSERQLALWNPKNMQEP--IALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHER-KCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNAD-PILISLKH-------GYIPG--------KNRDLKVVKK-NILDSKPAANKKSDLICAPKKTTDTAS--------------------VQNEAKLDEIL--------------------------------------------KEIKSIKDTICNQDERISKLEQQLAKMAA---------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUM4-1", "uniprot_id": "COR1C_MOUSE", "id": "Q9WUM4-1", "name": "Coronin-1C", "aln": "-MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLT---------EPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADG-NVFTTGFSRMSERQLALWNPKNMQEP--IALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHER-KCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNAD-PILISLKH-------GYIPG--------KNRDLKVVKK-NILDSKPAANKKSELSCAPKKPTDTAS--------------------VQNEAKLDEIL--------------------------------------------KEIKSIKETICSQDERISKLEQQLAKMAA---------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0R0D7-1", "uniprot_id": "COR1C_DANRE", "id": "B0R0D7-1", "name": "Coronin-1C-A", "aln": "MFKRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSAFCAVNPKFVALIVEASGGGAFMVLPLHKTGRIDKAYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLVTSMS---------EPVVVLEGHSKRVGVVTWHPTARNVLLSAGCDNMIIIWNVGTGESMITLEDHHPDIIYSICWNRNGSLICTACKDKKIRVIDPRKEEIIAEKDKAHEGARPMRAIFLSDG-KVFTTGFSRMSERQLALWDPENIDEP--VAVHEMDTSNGVLLPFYDPDTNVVYLCGKGDSSIRYFEITDEAPFVHYLNTFTTKEPQRGMGYMPKRGLDVNKCEIARFYKLHER-KCEPIIMTVPRKSDLFQDDLYPDTAGPDAPLEAEEWFEGKNGD-PVLISLKH-------GYIPG--------KNRDLKVVKK-NILDNKMSKNTEN-TTPAHKTATSTPS--------------------IKSEAKLEEVL--------------------------------------------KEIKSLRELVSSQEKRIGKLEEQLSKMDI---------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KEJ7-1", "uniprot_id": "A0A0B4KEJ7_DROME", "id": "A0A0B4KEJ7-1", "name": "Coronin", "aln": "MSFRVVRSSKFRHVYGQALKREQCYDNIRVSKSSWDSTFCAVNPKFLAIIVESAGGGAFIVLPHNKVGRIAADHPLVGGHKGPVLDIAWCPHNDNVIASGSEDCVVKVWQIPDGGLSRTLT---------EPVVDLVFHQRRVGLVLWHPSALNVLLTAGSDNQVVIWNVGTGEILVHIDS-HPDIVYSACFNWDGSKLVTTCKDKKIRIYDPRTAELESEA-MCHEGSKATRAIFLRHG-LIFTTGFNRSSERQYSLRAPDALNEP--IVMVELDTSNGVMFPLYDADTNMIYLCGKGDSVIRYFEVTPEPPFVHYINTFQTTEPQRGIGLMPKRGCDVTTCEVAKFYRMNNNGLCQVISMTVPRKSDLFQEDLYPDTLAEDAAITAEEWIDGKDAD-PITFSLKDRVSIVQGGYVSSS-------VNKSLPAKKAGNILNKPRGDSASSGATSSSAGGGNFASGNNNEAS------EGGPPAAVLSEKDLRTIQ--------------------------------------------DEIRKLKAIIVKQENRIRALEAKEDARNKNGSDAAPASAG----------AATSDGKASESANDHASTSAGTSKDED---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06440-1", "uniprot_id": "CORO_YEAST", "id": "Q06440-1", "name": "Coronin-like protein", "aln": "MSGKFVRASKYRHVFGQAAKKELQYEKLKVTNNAWDSNLLKTNGKFIAVNWNASGGGAFAVIPIEEVGKAPDQVPLFRGHTAQVLDTDFDPFNDHRIASGSDDSKIGIWDIPENYKFHDHVDEDGEPIDIKPVKFLTGHARKVGHVLYHPVAENVLASSSGDYTVKLWNVETGKDMITLKH--PDMVTSMSFSYDGNYLATVARDKKLRVWNIREEKIVSEG-PAHTGAKNQRVVWLGNSDRLATTGFSKLSDRQIGIWDAFNIEKGDLGGFYTVDQSSGILMPFYDEGNKILYLVGKGDGNIRYYEFQNDE--LFELSEFQSTEAQRGFAVAPKRMVNVKENEVLKGFKTVVDQRIEPVSFFVPRRSEEFQEDIYPDAPSNKPALTAEEWFSGKSVEGPILVSMRSIYDGSAPSFHEAKRPQQPTTQETALEEKKEQPKVEKPISESEKEVKQEAPKSPSPLKSASSSSTINHVLKEDNSINKLLKKSSDIDQVNNAEDPSRDTSGWEEADDEPAPIKIETPVTPTETKKDRTPKVEPSKELKPEPVSIATDRKQEQSLPQEEKSSEKTKSPEQEKSATPPSSITAAKTAITASSKEEPSAARTSPKSLGLKKSVEKLSTLVLQLEDVVDKLTKANLDKDERLLKLEQKIGELSK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.** **:***:*** *.: *:.::*:. :*** : .* :*:*: :::***** *:* .:.*: * . **.. *** : *.**: *****:*. : :*:**:. :** * * ::** * :** * *** ::. * : :*** **: :: :. .*:: . .:. :*. : *..:***:*: : * :: :* .* *:: *.::* .. : ****.: *:** .: . ::: . :* *.*:::*:** ...::** ****. ***:*. : :. :. * :.*.***:. *** :*. *: : :: : : : ***:*: **:*:***: . ...: ****:.**. : *: .*:: .: . : * * ::. . . * : .. .: : .*:: : .: :: * : ", "identical_positions": 133, "similar_positions": 166, "identity": "20.27%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030114-8", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1H285-1", "uniprot_id": "KBTB8_RAT", "id": "B1H285-1", "name": "Kelch repeat and BTB domain-containing protein 8", "aln": "--------------------------MDPFHACSILKQLKTMYDEGQLTDIVVEVDHGKTFSCHRNVLAAISPYFRSMFTSGLTESTQKEVRIIGVEAESMGLVLNYAYTSRVILTEANVQALFTTASIFQIPSIQDQCAKYMISHLDPQNSIGVFIFADHYGHQELGDRSKEYIRKKFLCVTKEQEFLQLTKDQLISILDSDDLNVDREEHVYESIIRWFEHEQNEREVHLPEIFAKCIRFPLMEDAFIEKIPPRFAQAIVKSCGEKG-PSNTNGCTQRLGMTASEMIICFDAAHKHSGKKQTVPCLDIVTGRVFKLCKPPNDLREVGILVSPDNDIYIAGGYRPSSSEVSIDHKAENDFWMYDHSTNRWLSKPSLLRARIGCKLVYCCGKMYAIGGRVYEGDGRNSLKSVECYDSRENCWMTVCAMPVAMEFHNAVEHKEKIYVLQGEFFLFYEPQKDYWGFLTPMTVPRIQGLAAVYKDSIYYIAGTCGNHQRVFTVEAYDIELNKWTRKKDFPCDQSINPYLKLVLFQNKLHLFVRATQVTVEEHIFRTSRKNSLYQYDDIADQWMKVYETPDRLWDLGRHFECAVAKLYPQCLQKVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UQV5-1", "uniprot_id": "KBTB8_MOUSE", "id": "Q3UQV5-1", "name": "Kelch repeat and BTB domain-containing protein 8", "aln": "MAASADLSKSSPTPNGIPSSDTANDTMDPFHACSILKQLKTMYDEGQLTDIVVEVDHGKTFSCHRNVLAAISPYFRSMFTSGLTESTQKEVRIIGVEAESMDLVLNYAYTSRVILTEANVQALFTTASIFQIPSIQDQCAKYMISHLDPQNSIGVFIFADHYGHQELGDRSKEYIRKKFLCVTKEQEFLQLTKDQLISILDSDDLNVDREEHVYESIIRWFEHEQSEREVHLPEIFAKCIRFPLMEDTFIEKIPPQFAQAIVKSCGE---PSNTSGCTQRLGMTASEMIICFDAAHKHSGKKQTVPCLDIVTGRVFKLCKPPNDLREVGILVSPDNDIYIAGGYRPSSSEVSIDHKAENDFWMYDHSTNRWLSKPSLLRARIGCKLVYCCGKMYAIGGRVYEGDGRNSLKSVECYDSRENCWMTVCAMPVAMEFHNAVEHKEKIYVLQGEFFLFYEPQKDYWGFLTPMTVPRIQGLAAVYKDSIYYIAGTCGNHQRVFTVEAYDIELNKWTRKKDFPCDQSINPYLKLVLFQNKLHLFVRATQVTVEEHIFRTSRKNSLYQYDDIADQWMKVYETPDRLWDLGRHFECAVAKLYPQCLQKVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFY9-1", "uniprot_id": "KBTB8_HUMAN", "id": "Q8NFY9-1", "name": "Kelch repeat and BTB domain-containing protein 8", "aln": "MAASADLSKSSPTPNGIPSSDPASDAMDPFHACSILKQLKTMYDEGQLTDIVVEVDHGKTFSCHRNVLAAISPYFRSMFTSGLTESTQKEVRIVGVEAESMDLVLNYAYTSRVILTEANVQALFTAASIFQIPSIQDQCAKYMISHLDPQNSIGVFIFADHYGHQELGDRSKEYIRKKFLCVTKEQEFLQLTKDQLISILDSDDLNVDREEHVYESIIRWFEHEQNEREVHLPEIFAKCIRFPLMEDTFIEKIPPQFAQAIAKSCVEKG-PSNTNGCTQRLGMTASEMIICFDAAHKHSGKKQTVPCLDIVTGRVFKLCKPPNDLREVGILVSPDNDIYIAGGYRPSSSEVSIDHKAENDFWMYDHSTNRWLSKPSLLRARIGCKLVYCCGKMYAIGGRVYEGDGRNSLKSVECYDSRENCWTTVCAMPVAMEFHNAVEYKEKIYVLQGEFFLFYEPQKDYWGFLTPMTVPRIQGLAAVYKDSIYYIAGTCGNHQRMFTVEAYDIELNKWTRKKDFPCDQSINPYLKLVLFQNKLHLFVRATQVTVEEHVFRTSRKNSLYQYDDIADQWMKVYETPDRLWDLGRHFECAVAKLYPQCLQKVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08CL3-1", "uniprot_id": "KBTB8_DANRE", "id": "Q08CL3-1", "name": "Kelch repeat and BTB domain-containing protein 8", "aln": "MAASGDVGKLLQVQNGTPAS-TSYNGVDALHACNILQQLKALYDEAQLTDIVVEVDHGKTFSCHRNVLAAISPYFRSMFTSGLTESSQREVRIVGVESESMHLVLDYAYTSRVTLTESNVQALFTAASIFQIPALQDQCAQFMISRLDPQNCIGVFMFADAYGHQELRERSQDYIRKKFLCVMGEQEFLHLTKDQLVSILNSDDLNVEKEEHVYESIVHWLEYDCSRREADLPEVFAKCIRLPLLEEAFLSRIPPAFALALSRDSSDKSRLNGTNGCSQRLGMTASEMIICFDAAHKHSGKKQTVPCLDIAAGKVYKLCKPPNDLREVGILISSENDIFIAGGYRPSNSEVCIDHRAESDFWQYEHAGNRWLPRSPMLRARIGCRLVHCCGKLYALGGRVYEGDGRNALKSVECYDARDNCWTAVSPMPVAMEFHSTIEYKDRIYVLQGEYFFCFDPRKDYWGHLPSMNIPRTQGLAALHKNCIYYIAGICRNHQRTFTVEVYDIEQNTWCRKRDLPFDQATSPYIKVLLLQGRLHLFVRATQVMVEEHVFRTSRKNSLYQYDDEADHWTKVYETPDRLWDLGRHFECVVAKLYPQCLQKVL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.:***.**:***::***.****************************************:*:****:***:*** ***:******* ***:*******:*******::*****::***:*****.****:*** ****** :**::********* *****:******:***:******::********::*:*:: ..**..***:******:**:*::*:.:*** ** *: :.. : ..*.**:********************************.:*:*:***************:*.:***:********.***.***:**.*** *:*: ****.:..:*******:**:****:**:***********:********:*:*** :*..********.::*:*::*******:*: ::*:*****.*..*.:** *****::*:.****** * **** ****.**** *.* **:*:* **: .**:*::*:*.:********** ****:************** **:* ******************.*************", "identical_positions": 426, "similar_positions": 120, "identity": "70.76%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030114-9", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09884-1", "uniprot_id": "DPOLA_HUMAN", "id": "P09884-1", "name": "DNA polymerase alpha catalytic subunit", "aln": "MAPVHGDDS--------LSDSGSFVSSRARREKKSKKGRQEALERLKKAKAGEKYKYEVEDFTGVYEEVDEEQYSKLVQARQDDDWIVDDDGIGYVEDGREIFDDDLEDDALDADEKGKDGKARNKDKRNVKKLAVTKPNNIKSMFIACAGKKTADKAVDLSKDGLLGDILQDLNTET-PQITPPPVMILKKKRSIGASPNPFSVH--TATAVPSGKIASP--VSRKEPPLTPVPLKRAEFAGDDVQVESTE----EEQESGAMEFEDGDFDEPMEVEEVDLEPMAAKAWDKESEPAEEVKQEADSGKGTVSYLGSFLPDVSCWDIDQEGDSSFSVQEVQVDSSHLPLVKGADEEQVFHFYWLDAYEDQYNQPGVVFLFGKVWIESAETHVSCCVMVKNIERTLYFLPREMKIDLNTGKETGTPISMKDVYEEFDEKIATKYKIMKFKSKPVEKNYAFEIPDVPEKSEYLEVKYSAEMPQLPQDLKGETFSHVFGTNTSSLELFLMNRKIKGPCWLEVKSPQLLNQPVSWCKVEAMALKPDLVNVIKDVSPPPLVVMAFSMKTMQNAKNHQNEIIAMAALVHHSFALDKAAPKPPFQSHFCVVSKPKDCIFPYAFKEVIEKKNVKVEVAATERTLLGFFLAKVHKIDPDIIVGHNIYGFELEVLLQRINVCKAPHWSKIGRLKRSNMPKLGGRSGFGERNATCGRMICDVEISAKELIRCKSYHLSELVQQILKTERVVIPMENIQNMYSESSQLLYLLEHTWKDAKFILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLLLHAFYENNYIVPDKQIFRKPQQKLGDEDEEIDGDTNKYKKGRKKAAYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQRVASEAQKVTEDGEQEQIPELPDPSLEMGILPREIRKLVERRKQVKQLMKQQDLNPDLILQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTYKGREILMHTKEMVQKMNLEVIYGDTDSIMINTNSTNLEEVFKLGNKVKSEVNKLYKLLEIDIDGVFKSLLLLKKKKYAALVVEPTSDGNYVTKQELKGLDIVRRDWCDLAKDTGNFVIGQILSDQSRDTIVENIQKRLIEIGENVLNGSVPVSQFEINKALTKDPQDYPDKKSLPHVHVALWINSQGGRKVKAGDTVSYVICQDGSNLTASQRAYAPEQLQKQDNLTIDTQYYLAQQIHPVVARICEPIDGIDAVLIATWLGLDPTQFRVHHYHKDEENDALLGGPAQLTDEEKYRDCERFKCPCPTCGTENIYDNVFDGSGTDMEPSLYRCSNIDCKASPLTFTVQLSNKLIMDIRRFIKKYYDGWLICEEPTCRNRTRHLPLQFSRTGPLCPACMKATLQPEYSDKSLYTQLCFYRYIFDAECALEKLTTDHEKDKLKKQFFTPKVLQDYRKLKNTAEQFLSRSGYSEVNLSKLFAGCAVKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33609-1", "uniprot_id": "DPOLA_MOUSE", "id": "P33609-1", "name": "DNA polymerase alpha catalytic subunit", "aln": "MAPMHEEDCKLEA--SAVSDSGSFAASRARREKKSKKGRQEALERLKKAKAGEKYKYEVEDLTSVYEEVDEEQYSKLVQARQDDDWIVDDDGIGYVEDGREIFDDDLEDDALDTCGKGSDGKAHRKDRKDVKKPSVTKPNNIKAMFIASAGKKTTDKAVDLSKDDLLGDILQDLNTET-AQITPPPVLIPKKKRSTGALLNPFSVH--TPKAIPSGKPASP--VLRNEPLLTPIPLKRAELAGELAQPECPE----DEQELGVMEFEDGDFDESMDTEKVDEKPVTAKTWDQETEPVERVEHEADPERGTTSYLENFLPDVSCWDIDQDDES--IPQEVQVDSSNLPLVKGADDEQVFQFYWLDAYEDPYNQPGVVFLFGKVWIESVKTHVSCCVMVKNIERTLYFLPREMKFDLNTGKETAIPVTMKDVYEEFDSKISAKYKIMKFKSKIVEKNYAFEIPDVPEKSEYLEVRYSAEVPQLPQNLKGETFSHVFGTNTSSLELFLMNRKIKGPCWLEVKNPQLLNQPISWCKFEVMALKPDLVNVIKDVSPPPLVVMSFSMKTMQNVQNHQHEIIAMAALVHHSFALDKAPPEPPFQTHFCVVSKPKDCIFPCDFKEVISKKNMKVEIAATERTLIGFFLAKVHKIDPDILVGHNICSFELEVLLQRINECKVPYWSKIGRLRRSNMPKLGSRSGFGERNATCGRMICDVEISAKELIHCKSYHLSELVQQILKTERIVIPTENIRNMYSESSYLLYLLEHIWKDARFILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLLLHAFYENNYIVPDKQIFRKPQQKLGDEDEEIDGDTNKYKKGRKKATYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQRVTSEVQKATEDEEQEQIPELPDPNLEMGILPREIRKLVERRKQVKQLMKQQDLNPDLVLQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTYKGREILMHTKDMVQKMNLEVIYGDTDSIMINTNSTNLEEVFKLGNKVKSEVNKLYKLLEIDIDAVFKSLLLLKKKKYAALVVEPTSDGNYITKQELKGLDIVRRDWCDLAKDTGNFVIGQILSDQSRDTIVENIQKRLIEIGENVLNGSVPVSQFEINKALTKDPQDYPDRKSLPHVHVALWINSQGGRKVKAGDTVSYVICQDGSNLTATQRAYAPEQLQKLDNLAIDTQYYLAQQIHPVVARICEPIDGIDAVLIALWLGLDSTQFRVHQYHKDEENDALLGGPAQLTDEEKYKDCEKFKCLCPSCGTENIYDNVFEGSGLDMEPSLYRCSNVDCKVSPLTFMVQLSNKLIMDIRRCIKKYYDGWLICEEPTCCSRLRRLPLHFSRNGPLCPVCMKAVLRPEYSDKSLYTQLCFYRYIFDADCALEKLT-EHEKDKLKKQFFPLRVLQDYRKVKNIAEQFLSWSGYSEVNLSKLFANYAGKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FB68-1", "uniprot_id": "E7FB68_DANRE", "id": "E7FB68-1", "name": "DNA polymerase", "aln": "MAPVSNPDKDMDGGDCDASDTCGIAASRSRREKKEKVGRKSALEQLKRAKKGEKVKYEVEEFTSIYDEVDEEQYSKIVRERQDDDWIIDDDGTGYVEDGREIFDEELDDDALGP--KSKQAAKGGDSKKNVKKSSVSKPNSIKSMFMNSNVKKPAEKHVDLSQDDLLGDILQDLHSEKSVVLTPPPIITLKKKKTLGSPMNPFSVKPQMPKELPEVHVSKPRPVVTRVPPADPSPRSAASVEPSKATAAQIKKPKIEEPEEEAIEFDEMDFDEPMEAENLEEEPVKEKAEP-ETKPIVKVEPKTEPQD---KMLISGLVGGMGWEKMEEGKPIETPVEVQVDSSQLPLVEGPDGDMVFRFYWLDAFEDQYNQPGVVFLFGKVWIESAEAHVSCCVAVKNIERTMYLLPREHKVNLATG-EKGVAVGMMDVYKEFN-EISEKFKIMKFKSKPVTKNYAFEIPDIPSQSEYLEVKYSAEIPSLPSDLKGTTFSHVFGTNTSSLEHFLLNRKIRGPCWLDVTTPQLSNQPISWCKVEAVAQKSDLISVVKDLSPPPLVVMSISLKTVQNPKTHQNEIVSIAALVHHTFPLDKAPPRPPFQTHFCVVSKPNDCVFPYDFKDAVRKKNGIVEIAGTERALLGFFLAKMHKIDPDVLVGHDIFGFDLEVLLQRINVCKVPHWSKIGRLRRANMPKLGGRSGFAEKSATCGRLVCDIEISAKELIRCKSYNLTELVSQILKAERPVVPPENIRNFYSDSTHLLYLLELTWMDAKLILQIMCELNVLPLALQITNIAGNVMSRTLMGGRSERNEYLLLHAFHERDFIVPDKQFFKKAQQDLG-EDEEGDSGKGKSNKTRKKAAYAGGLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVERGATNTRKKTEEDEDE-IPELPDQSLEMGILPKEIRKLVERRRQVKQLMKEPDLNPDLYLQYDIRQKALKLTANSMYGCLGFSFSRFYAKPLAALVTHKGREILMHTKEMVQRMNLEVIYGDTDSIMINTNSTNLEEVFKLGNKVKSEVNKLYKLLEIDIDGVFKSLLLLKKKKYAALMVEPQGDGKYTTKQELKGLDIVRRDWCDLAKECGNYVIGQILSDQNRDTIIENIQKHLIEIGEKVANGNIPLNMFEIHKSLTKEPQDYPDKKSLPHVHVALWINSQGGKKVKAGDTVSYVICQDGSNLAASQRAYTLEQLQKQPGLNLDTQYYLSQQVHPVVGRICEPIEGIDAVLIATWLGLDPSHFRAQQQQREDEADDFLGAPAQLTDEERYRDCERFTFTCPDCGTENIYDNVFEGTGSTLQLSLKSCCHVPCGGSPMDHQVQIGNKLQLDIRRHIRRYYSGWLLCEDQACRNRIRRLPIAFSRSGPICPACLRSTLKPEYSEKALYNQLSFYRYIFDWEYAINKVLTGDDKLKFKSKEWK-EEMEVYKKLKGVTDNILATSGYSEVNLAKLFQAFITLK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***: * **: .:.:**:*****.* **:.***:**:** *** *****::*.:*:*********:*: *******:**** ***********::*:****.. *..:. ..:::*** :*:***.**:**: . **.::* ****:*.*********::*. :****:: ***:: *: *****: .. :*. : :.* * . * * * . *.. . . : :* * .:**:: ****.*:.*::: :*: *: *::* .*: :::. . * . * . *: ::... *******:****:*.* : **:******:** *****************.::****** *******:*:**** *.:* ** *.. .: * ***:**: :*: *:******** * *********:*.:******:****:*.**.:*** ************** **:****:*****:*..*** ***:****.*.:* *.**:.*:**:********::*:**:** :.**:**:::******:*.****.*.****:********:**:** **:.: *** **:*.***:*:******:******::***:* .*:********* **.*:*******:*:******.****.*:.*****::**:********:****:*:***.****:** *:* ***:*:**:*: ****** * **::***********************:**************:******:*.::******:*:*.**.** **** *....* :* ****:*****************************************:* :::.:* **: *:* ****** .*******:*********:*******: ****** ************************:*************:**********:***:************************************************.****************:*** .**:* ********************: **:*********.****:*****:******:* **.:*:. ***:*:***:******:*****************:*******************:*:****: ***** .* :******:**:****.******:******** *****.::**.:: ::::* * :**.********:*:***:*. ** ***********:*:* :: ** *.:: * **: . **:.*** :**** *::**.***:**: :* .* *:**: ***.**:**.*:::.*:****:*:**.**.******* : *::*: .:* *:*.: : . :: *:*:*. ::::*: ********:*** .", "identical_positions": 957, "similar_positions": 329, "identity": "64.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030115-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04797-1", "uniprot_id": "G3P_RAT", "id": "P04797-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "--------------------------------------------------------------------------------------------------------------------MVKVGVNGFGRIGRLVTRAAFSC--DKVDIVAINDPFIDLNYMVYMFQYDSTHGKFNGTVKAENGKLVINGKPITIFQERDPANIKWGDAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIVSNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTCRLEKPAKYDDIKKVVKQAAEGPLKGILGYTEDQVVSCDFNSNSHSSTFDAGAGIALNDNFVKLISWYDNEYGYSNRVVDLMAYMA--SKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2K8S2-1", "uniprot_id": "A0A0G2K8S2_RAT", "id": "A0A0G2K8S2-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "--------------------------------------------------------------------------------------------------------------------MVKVGVNGFGRIGHLVTRAAFSC--DKVDIVAINDPFIDLNYMVYMFQYDSTHGKFNGTVKAENGKLVINGKPITIFQERDPANIKWGDAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIVSNASCTTNCLAPLGKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTCRLEKPAKYDDIKKVVKQVAEGPLKGILGYTEDQVVSCDFNSNSHSSTFDAGAGIALNDNFVKLISWYDNEYGYSNRVVDLMAYMA--SKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1M4G6-1", "uniprot_id": "F1M4G6_RAT", "id": "F1M4G6-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "-----------------------------------------------MTAASS----------------CAVPA------------------LSHRQDGGG-------------------GVSGFCRIGCLVTRAAFSSASGKVEIVAINDPFIDLNYMIYMFQYDSTRGKFNGTVKAEDGKLVTNGKAITIFQERDPANIKWGDAGAEYVVESTGNFTTMEKAGAHLKGGAKRVIISALLANAPMSVMGVNHEKYDNSLKIVSNASWPRSSMTTLASWKG-----------SIHAVTTTQKSVDGPSESCGVMG-GAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFCVPTPNVSIVDLTCCLEKPAKCDDIKKVVKQASEGPLKGILGYTEDQVFSCNFNSSFHSSTFDAGAGIALNDNFVKLISWYDNEYGYSNRLGNLMAYMA--SKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2K3I6-1", "uniprot_id": "A0A0G2K3I6_RAT", "id": "A0A0G2K3I6-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "MEDKIFTHACTGCGEEDRLEIDADTANTTQDRCHVSGHLHVHHPNSIAAAASSTPCTTSNLLAAVVLRTSTIPAGLPNAMMPCLQLPAKESTLFKHLEGKRQSHLLLQCQPCLIDKMVKLSVNGFGRIGNLVTRAAFCSASGKVDIVAINDPFINLNYMVYIFQYDSTHGKLNGTVKAENGKLVINGKPITIFQEQDPANIKWGDAGAEYVVESTGVFTTVEKAGTHLKGGGKRVFISAPSADAPMFVMGVNHKKYDNSLKIVSNTSCTTNCLAPLAKVIPDNFGIVEGLMTTVHAITAPQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPHVSIMDLTCCLEKPAKYDDIKKVVKQAPEGPLKDILGYTEDQVVSCDFNSNSHSSTFDAGAGIALNDNFVKLISWYDNEYGYSNRVVDLMAYMA--SKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16858-1", "uniprot_id": "G3P_MOUSE", "id": "P16858-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "--------------------------------------------------------------------------------------------------------------------MVKVGVNGFGRIGRLVTRAAICS--GKVEIVAINDPFIDLNYMVYMFQYDSTHGKFNGTVKAENGKLVINGKPITIFQERDPTNIKWGEAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIVSNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEDQVVSCDFNSNSHSSTFDAGAGIALNDNFVKLISWYDNEYGYSNRVVDLMAYMA--SKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "S4R1W1-1", "uniprot_id": "S4R1W1_MOUSE", "id": "S4R1W1-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "--------------------------------------------------------------------------------------------------------------------MVKVGVNGFGRIGRLVTRAAICS--GKVEIVAINDPFIDLNYMVYMFQYDSTHGKFNGTVKAENGKLVINGKPITIFQERDPTNIKWGEAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIVSNASCTTNCLSPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTCRLENPAKYDDIKKVVKQASEGPLKGILGYTEDQVVSCDFNSNSHSSTFDAGAGIALNDNFVKLISWYDNEYGYSNRVVDLMAYMA--SKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1D5RLD8-1", "uniprot_id": "A0A1D5RLD8_MOUSE", "id": "A0A1D5RLD8-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "--------------------------------------------------------------------------------------------------------------------MVKVGVNGFGRIGRLVTRAATCS--GKVEIVAINDPFIDLNYMVYMFQYDSTHGKFNGTVKAENGKLVINGKPITIFQERDPTNIKWGEAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIVSNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSIVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEDQVVSCDFNSNSHSSTFDAGAGIALNDNFVKLISWYDNEYGYSNRVVDLMAYMA--SKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04406-1", "uniprot_id": "G3P_HUMAN", "id": "P04406-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "-----------------------------------------------MG-------------------------------------------------------------------KVKVGVNGFGRIGRLVTRAAFNS--GKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMA--SKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZME3-1", "uniprot_id": "D3ZME3_RAT", "id": "D3ZME3-1", "name": "glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGVNHEKYDNSLKIVSNASCTTNCLGPLGKVIHDNFGIMEGLMTTVHAITATQKTVDGPSGKLWSDGRGAAQNIIPASTGAAEAVGKVIPELNGKLTGMAFHVPTPNVSVVDLTCCLEKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSFTFDAGAGIALNDNFEKLISWYDNEYGYSNRVVTSWPTWPPRSKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5XJ10-1", "uniprot_id": "G3P_DANRE", "id": "Q5XJ10-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "aln": "--------------------------------------------------------------------------------------------------------------------MVKVGINGFGRIGRLVTRAAFLT--KKVEIVAINDPFIDLDYMVYMFQYDSTHGKYKGEVKAEGGKLVIDGHAITVYSERDPANIKWGDAGATYVVESTGVFTTIEKASAHIKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLTVVSNASCTTNCLAPLAKVINDNFVIVEGLMSTVHAITATQKTVDGPSGKLWRDGRGASQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTVRLEKPAKYDEIKKVVKAAADGPMKGILGYTEHQVVSTDFNGDCRSSIFDAGAGIALNDHFVKLVTWYDNEFGYSNRVCDLMAHMA--SKE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07486-1", "uniprot_id": "G3P1_DROME", "id": "P07486-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase 1", "aln": "--------------------------------------------------------------------------------------------------------------------MSKIGINGFGRIGRLVLRAAIDKG---ASVVAVNDPFIDVNYMVYLFKFDSTHGRFKGTVAAEGGFLVVNGQKITVFSERDPANINWASAGAEYVVESTGVFTTIDKASTHLKGGAKKVIISAPSADAPMFVCGVNLDAYSPDMKVVSNASCTTNCLAPLAKVINDNFEIVEGLMTTVHATTATQKTVDGPSGKLWRDGRGAAQNIIPAATGAAKAVGKVIPALNGKLTGMAFRVPTPNVSVVDLTVRLGKGATYDEIKAKVEEASKGPLKGILGYTDEEVVSTDFFSDTHSSVFDAKAGISLNDKFVKLISWYDNEFGYSNRVIDLIKYMQ--SKD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07487-1", "uniprot_id": "G3P2_DROME", "id": "P07487-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase 2", "aln": "--------------------------------------------------------------------------------------------------------------------MSKIGINGFGRIGRLVLRAAIDKG---ANVVAVNDPFIDVNYMVYLFKFDSTHGRFKGTVAAEGGFLVVNGQKITVFSERDPANINWASAGAEYIVESTGVFTTIDKASTHLKGGAKKVIISAPSADAPMFVCGVNLDAYKPDMKVVSNASCTTNCLAPLAKVINDNFEIVEGLMTTVHATTATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPALNGKLTGMAFRVPTPNVSVVDLTVRLGKGASYDEIKAKVQEAANGPLKGILGYTDEEVVSTDFLSDTHSSVFDAKAGISLNDKFVKLISWYDNEFGYSNRVIDLIKYMQ--SKD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00359-1", "uniprot_id": "G3P3_YEAST", "id": "P00359-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase 3", "aln": "--------------------------------------------------------------------------------------------------------------------MVRVAINGFGRIGRLVMRIALSRP--NVEVVALNDPFITNDYAAYMFKYDSTHGRYAGEVSHDDKHIIVDGKKIATYQERDPANLPWGSSNVDIAIDSTGVFKELDTAQKHIDAGAKKVVITAPSSTAPMFVMGVNEEKYTSDLKIVSNASCTTNCLAPLAKVINDAFGIEEGLMTTVHSLTATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPELQGKLTGMAFRVPTVDVSVVDLTVKLNKETTYDEIKKVVKAAAEGKLKGVLGYTEDAVVSSDFLGDSHSSIFDASAGIQLSPKFVKLVSWYDNEYGYSTRVVDLVEHVA---KA", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P00358-1", "uniprot_id": "G3P2_YEAST", "id": "P00358-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase 2", "aln": "--------------------------------------------------------------------------------------------------------------------MVRVAINGFGRIGRLVMRIALQRK--NVEVVALNDPFISNDYSAYMFKYDSTHGRYAGEVSHDDKHIIVDGHKIATFQERDPANLPWASLNIDIAIDSTGVFKELDTAQKHIDAGAKKVVITAPSSTAPMFVMGVNEEKYTSDLKIVSNASCTTNCLAPLAKVINDAFGIEEGLMTTVHSMTATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPELQGKLTGMAFRVPTVDVSVVDLTVKLNKETTYDEIKKVVKAAAEGKLKGVLGYTEDAVVSSDFLGDSNSSIFDAAAGIQLSPKFVKLVSWYDNEYGYSTRVVDLVEHVA---KA", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P00360-1", "uniprot_id": "G3P1_YEAST", "id": "P00360-1", "name": "Glyceraldehyde-3-phosphate dehydrogenase 1", "aln": "--------------------------------------------------------------------------------------------------------------------MIRIAINGFGRIGRLVLRLALQRK--DIEVVAVNDPFISNDYAAYMVKYDSTHGRYKGTVSHDDKHIIIDGVKIATYQERDPANLPWGSLKIDVAVDSTGVFKELDTAQKHIDAGAKKVVITAPSSSAPMFVVGVNHTKYTPDKKIVSNASCTTNCLAPLAKVINDAFGIEEGLMTTVHSMTATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPELQGKLTGMAFRVPTVDVSVVDLTVKLEKEATYDQIKKAVKAAAEGPMKGVLGYTEDAVVSSDFLGDTHASIFDASAGIQLSPKFVKLISWYDNEYGYSARVVDLIEYVA---KA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** * . .::**:* . ..: .*.. ::*: *:.**:***** . * * ****::****:*****:* *:******** *** .**::*** * : :. *:** *: ...* :*.:****:. *.* :* .. .: *** *** *. :* **::*****:*** *: * ", "identical_positions": 84, "similar_positions": 52, "identity": "18.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030115-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62868-1", "uniprot_id": "ROCK2_RAT", "id": "Q62868-1", "name": "Rho-associated protein kinase 2", "aln": "MSRPPPTGKMPGAPEAAAGDGAGAGRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDTEISKHAKNLICAFLTDREVRLGRNGVEEIKSASFFKNDQWNWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYFRENLLLSDSPPCRENDAIQTRKS--EESQEIQKKLYALEEHLSSEVQAKEELEQKCKSINTRLEKTAKELEEEITFRKNVESTLR----QLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQSSQISTEKVNQLQKQLDEANALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRISGLEEDLKTGKTLLAKVELEKRQLQEKLTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKTT-KARLADKNKIYESIEEAKSEAMKEMEKKLLEERSLKQKVENLLLEAEKRCSILDCDLKQSQQKLNELLKQKDVLNEDVRNLTLKIEQETQKRCLMQNDLKMQTQQVNTLKMSEKQIKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEENEEKTKLCKELQQKKQDLQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDTQEQLSKLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKEP------VKRGSDTDVRRKEKENRKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIG-MDSSSIGSGPGDAEPDDG------FPESRLEGWLSLPVRNNTKK-FGWVKKYVIVSSKKILFYDSEQDKE-QSNPYMVLDIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEPEFPVEPV--------GEKSNYICHKGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECSRCHIKCHKDHMDKKEEIIAPCKVYYDISSAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRPSRQLAPNKPS----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70336-1", "uniprot_id": "ROCK2_MOUSE", "id": "P70336-1", "name": "Rho-associated protein kinase 2", "aln": "MSRPPPTGKMPGAPEAAPGDGAGAGRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDTEISKHAKNLICAFLTDREVRLGRNGVEEIKQHPFFKNDQWNWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYFRENLLLSDSPPCRENDAIQTRKS--EESQEIQKKLYALEEHLSSEVQAKEELEQKCKSINTRLEKTAKELEEEITLRKSVESTLR----QLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQSSQISTEKVNQLQKQLDEANALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRISGLEEDLKTGKALLAKVELEKRQLQEKLTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKTT-KARLADKNKIYESIEEAKSEAMKEMEKKLLEERSLKQKVENLLLEAEKRCSILDCDLKQSQQKLNELLKQKDVLNEDVRNLTLKIEQETQKRCLMQNDLKMQTQQVNTLKMSEKQIKQENNHLMEMKMNLEKQNTELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEENEEKTKLCKELQQKKQDLQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDTTIASLEETNRTLTSDVANLANEKEELNNKLKDSQEQLSKLKDEEMSAAAIKAQFEKQLLNERTLKTQAVNKLAEIMNRKEP------VKRGSDTDVRRKEKENRKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIG-MDSSSIGSGPGDAEPDDG------FPESRLEGWLSLPVRNNTKK-FGWVKKYVIVSSKKILFYDSEQDKE-QSNPYMVLDIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEPEFPVEPV--------GEKSNYICHKGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYDISSAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRPSRQLAPNKPS----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75116-1", "uniprot_id": "ROCK2_HUMAN", "id": "O75116-1", "name": "Rho-associated protein kinase 2", "aln": "MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENLLLSDSPSCRETDSIQSRKN--EESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEITLRKSVESALR----QLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKAT-KARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKEP------VKRGNDTDVRRKEKENRKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIG-LDSSSIGSGPGDAEADDG------FPESRLEGWLSLPVRNNTKK-FGWVKKYVIVSSKKILFYDSEQDKE-QSNPYMVLDIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPV--------GEKSNYICHKGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYDISTAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRPSRQLAPNKPS----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U3E8-1", "uniprot_id": "A0AB32U3E8_DANRE", "id": "A0AB32U3E8-1", "name": "Rho-associated protein kinase 2", "aln": "MS--------LGAERRMEN------RLRQLEAMIKDPRSAINLESLLDSMNALVLDLDFPALRKNKNIENFLNRYEKVMNHIRELQMRPEDFDRVKVIGRGAFGEVQLVRHKASQKVYAMKVLSKFEMIKRSDSAFFWEERDIMAFADSPWVVQLCCAFQDDRSLYMVMEYMPGGDLVNLTSTYDVPEKWAKFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDRYGHLKLADFGTCMKMDGTGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFIYEMLVGDTPFYADSLVGTYSKIMDHKNSLNFPDDVEISQEGKNIICAFLTDREVRLGRSGVEEIKRHPFFRNDQWTFSTIRETAAPVVPELSSDIDTSNFDEIEEDKGEVETFPTPKAFVGNQLPFVGFTYFKENQLLNAVNSSAMKNDHPVSNR--EDNLALQKKLHCLEEQLNNEMQAKDELEQKYRSNSNRLEKITKELDEEMNSRKGLESTLR----QLEREKALLQHKSVESHRRAESEADRKRCLENEVNSLRDQLDEMKKKNQNSHISNEKNIHLQKQLDEANALLRAESEVATRMRKTQTESSKQLQQLEAHVRELQDKCCMLENSKLTLERENISLQAALDTEKREQTQGSETISDLQARITGMEDEVRQMRQALSKAETEKRQLQEKLTDMEKEKSNNQIDMTYKLKMLQQGLEQEEAAHKAT-KARLADKNMISESIEGAKSEAVKELEQKLQEERSSKQRVENRVLELEKKNSMLDCDYKQSLQKLEELRRHKERLTEEVKNLNLKIEQEVQKRTLTQNDLKVQNQQLSTLRTSEKQLKQEINHILEIKRSLEKQNMELRKERQDSDGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKNKLYKDVQQNLQELQEERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHRQELAEKDTTISSLEEANRTLTSDVANLANEKEEFNNKLKEAEDYLQNLKNEEQSITQVKLALEKQLQSERTLKTQAVNKLAEIMNRKEVRG--GGSRRGNDTDVRRKEKENRKLQLELRSEREKLNSTIIKYQREINDIQAQLLDESQVRIELQMALDSKDSDIEQLRSLLNSLNVQSLDSASMSSGP-DMDTDES------LLEIRLEGWLSLPVRNNTKR-FGWERKYVVVSSKKILFYNSEQDKE-HSNPYMVLDIDKLFHVRSVTQTDVYRADAKEIPRIFQILYANEGESKKEQELEPLP---------GDKSSYICHKGHEFIPTLYHFPTNCEACTKPLWNMFKPPPALECRRCHIKCHKDHMDKKEEVIAPCRV--DMSTAKNLLLLASSQEDQQKWVSRLMKKIPKKPPAPDAPHRSSPRVPVKVQSSQSMRRPSRQIPAGKPRFVHSVTEPAACTEKSGFIYHKGHEFIPLFFHFPANCEACPKPLWNMFKPPLALECQRCQIKCHKEHMDKREDCLKPCAEQFNPQLNTG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXE3-1", "uniprot_id": "Q9VXE3_DROME", "id": "Q9VXE3-1", "name": "Rho-associated protein kinase", "aln": "MPAG-----RETVTKQRSMDVERRRRANTLEREMRDPTSICNVDCLLDTVSALVSDCDHESLRRLKNIEQYAAKYKPLAMQINQLRMNVEDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKFEMMKRPDSAFFWEERHIMAHANSEWIVQLHFAFQDAKYLYMVMDFMPGGDIVSLMGDYDIPEKWAIFYTMEVVLALDTIHNMGFVHRDVKPDNMLLDSYGHLKLADFGTCMRMGANGQVVSSNAVGTPDYISPEVLQSQGVDNEYGRECDWWSVGIFLYEMLFGETPFYADSLVGTYGKIMDHKNSLSFPPEVEISEQAKALIRAFLTDRTQRLGRYGIEDIKAHPFFRNDTWSFDNIRESVPPVVPELSSDDDTRNFEDIERDEKPEEVFPVPKGFDGNHLPFIGFTYTGDYQLLSSDTVDAESKEANVANSGAASNNHGHGHNHRHRPSNSNELKRLEALLERERGRSEALEQQDAGLRQQIELITKREAELQRIASEYEKDLALRQHNYKVAMQKVEQEIELRKKTEALLVETQRNLENEQKTRARDLNINDKVVSLEKQLLEMEQSYKTETENTQKLKKHNAELDFTVKSQEEKVRDMVDMIDTLQKHKEELGQENAELQALVVQEKNLRSQLKEMHKEAENKMQTLINDIERTMCREQKAQEDNRALLEKISDLEKAHAG----LDFELKAAQGRYQQEVKAHQETEKSRLVSR-------EEANLQEVKALQSKLNEEKSARIKADQHSQEKERQLSMLSVDYRQIQLRLQKLEGECRQESEKVAALQSQLDQEHSKRNALLSELSLHSSEVAHLRSRENQLQKELSTQREAKRRFEEDLTQLKSTHHEALANNRELQAQLEAEQCFSRLYKTQANENREESAER-------LSKIEDLEEERVSLKHQVQVAVARADSEALARSIAEETVADLEKEKTIKELELKDFVMKHRNEINAKEAALATLKEAENELHKKLGQKAAEYEDLVQQHKKQQEELALMRS---SKDEEITKLLDKCKNEVLLKQVAVNKLAEVMNRRDSDLPKQKNKARSTAELRKKEKEMRRLQQELSQERDKFNQLLLKHQ----DLQQLCAEEQQLKQKMVMEIDCKATEIENLQSKLN-------ETASLSSADNDPEDSQHSSLLSLTQDSVFEGWLSVPNKQNRRRGHGWKRQYVIVSSRKIIFYNSDIDKHNTTDAVLILDLSKVYHVRSVTQGDVIRADAKEIPRIFQLLYAGEGASHRPDEQSQLDVSVLHGNCNEERPGTIVHKGHEFVHITYHMPTACEVCPKPLWHMFKPPAAYECKRCRNKIHKEHVDKHD-PLAPCKLNHDPRSARDMLLLAATPEDQSLWVARLLKRIQKSGYKAASYNNNS-TDGSKISPSQSTRSSYKPYAVNVQR---SATLPANSSLK--------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . . * . ** ::** * *::.*** :.:** * *. :**: ***::: :*: : :*. *:*. **:. :*:** ************:*.:***** ******:**.*********.***.*:* *:*** **** : *****::*****:*.* . **:***** *** *******:**.**::************ :************:*. .* * ...*************:*** *. ***********:*::***.*:************.********* ** :.***:..* :* ****** **** *:*:*: .**:** * :..***:..********* *: **::** *: *.** **.* **:***:**** : **. .. : .. : : : . ..*:: : * :: :. . **: * ::: . *: *: : *:: ** **: ::.: * : :: * : . : :*:: :* . . .:* *::** * : ::*:: : :::* ::* . ::. * : *:: * *:. * * :* .**: : *:. ::: .* .: : :: : :::. *.: ::* * *:::*:** ::. : ::** * :** *: * *:**..: * *: : :* ::.** **:: : :.:: * *:: *:*. * :* ::::* . .*.* * :::** .** .:*.::..:: *: *:*:::* . * * :*:: :*:. :::: .: :*** ****** ** *****..* :** *: .: ::*::** ** *:::::::**** ******** :****** :****:*::: :*::*: *::::::*:*::. * ..:.: * * *:: :: *. :: * ::. * : .: .* ** *******:***:: : . :::*:**** *:*: ** .**:*:.. ::*:* ::* :*.*:: :: * :*.* ::**:*:* *: :::*:.*. * : .: : :*****:* ::* :: .** ::**:***:**:**:*: **. ::. ::**:.*::***.*** ** ************:***.** *:: * ::.. * ******: **:** **.* ****:*****.* ** **: * **:*:**:: :***:: * :*:::**** : *:*. **:**:*:* *. . . ..* *:. .** * . : . . ", "identical_positions": 543, "similar_positions": 426, "identity": "36.06%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030116-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62986-1", "uniprot_id": "ESR2_RAT", "id": "Q62986-1", "name": "Estrogen receptor beta", "aln": "MEIKNSPSSLS--SPASYNCSQSILP--------LEHGPIYIPSSYVDNRHEYSAMT---FYSPAVMNYS-VPGSTSNLDGGPVRL---STSPNVLWPTSGHLSPLATHCQSSLLYAEPQ-KSPWCEAR----SLEHTLPVNRETLKRKLSGSSCASPVTSPNAKRDAHFCPVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGS--------RRERCGYRIVRRQR------SSSEQVHCLSKAKRNGGHAPRVKELLLST----------LSPEQLVLTLLEAEPPNVLVSRPS-MPFTEASMMMSLTKLADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSS-MYPLASANQEAESSRKLTHLLNAVTDALVWVIAKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMKCKNVVPVYDLLLEMLNAHTLRG----------------------YKSSISGSECSS-TEDSKNKESSQNLQSQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08537-1", "uniprot_id": "ESR2_MOUSE", "id": "O08537-1", "name": "Estrogen receptor beta", "aln": "MEIKNSPSSLT--SPASYNCSQSILP--------LEHGPIYIPSSYVESRHEYSAMT---FYSPAVMNYS-VPSSTGNLEGGPVRQ---TASPNVLWPTSGHLSPLATHCQSSLLYAEPQ-KSPWCEAR----SLEHTLPVNRETLKRKLGGSGCASPVTSPSAKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGS--------RRERCGYRIVRRQR------SASEQVHCLNKAKRTSGHTPRVKELLLNS----------LSPEQLVLTLLEAEPPNVLVSRPS-MPFTEASMMMSLTKLADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTARFRELKLQHKEYLCVKAMILLNSS-MYPLATASQEAESSRKLTHLLNAVTDALVWVISKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMKCKNVVPVYDLLLEMLNAHTLRG----------------------YKSSISGSECCS-TEDSKSKEGSQNLQSQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92731-1", "uniprot_id": "ESR2_HUMAN", "id": "Q92731-1", "name": "Estrogen receptor beta", "aln": "MDIKNSPSSLN--SPSSYNCSQSILP--------LEHGSIYIPSSYVDSHHEYPAMT---FYSPAVMNYS-IPSNVTNLEGGPGRQ---TTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQ-KSPWCEAR----SLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGS--------RRERCGYRLVRRQR------SADEQLHCAGKAKRSGGHAPRVRELLLDA----------LSPEQLVLTLLEAEPPHVLISRPS-APFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSS-MYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLRG----------------------CKSSITGSECSP-AEDSKSKEGSQNPQSQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B359-1", "uniprot_id": "A0A8M2B359_DANRE", "id": "A0A8M2B359-1", "name": "", "aln": "MSSSPGPAPVLDSSKADRGASPALLPRLYASPLGMDNQTVCIPSPYVEACQDYSPPHGGEFNHGALTLYSPVSSAVLGFHRPPVSESLVPLSPTILWP------PHSLHCPPPLAYSETRSHSAWEEAKTHTLSQSSSVLSHTKLLGQQLEGDNGLNPSASIVGKGDTHFCAVCHDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKSRRKSCQACRLRKCYEVGMMKCGMQLTLRFCVRRERCSYRGARHRRNPQIRDSSGGVVGLRGQSQQHLEFPLSPSQHLFPSGGRAEGRGLNYSPEQLVSCILEAEPPQIYLREPVKKPYTEASMMMSLTSLADKELVLMISWAKKIPGFVELTLSDQVHLLECCWLDILMLGLMWRSVDHPGKLIFTPDLKLNREEGNCVEGIMEIFDMLLATTSRFRELKLQREEYVCLKAMILLNSNNCSSLPQTPEDVESRGKVLNLLDSVTDALVWIISRTGLSSQQQSIRLAHLLMLLSHIRHLSNKGIEHLSNMKRKNVVLLYDLLLEMLDANTSQSSRMLEDRQQSPENLHTSRPQPDLKDSDQETPHSPRAEETVNKTLHSSLLREDMDTN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . .*:.: * :. ..* ::** ::: .: ***.**: ::*.. * *: ** :.. . .:. * . **.:*** * * . *:*.: :*.* **: * . :: : : * ::: *. .* :. .* *:***.** ******************************************.******************:*** *****.** .*::* *:. : .:::: .. : *: : ****** :******:: : .* *:**********.******* **.***********:* ***:***.**:::**:******:********:*** *:*:**:*****:**********:********::**:*:********. .* : ::.:* *: :**::*******:*:::*:******:***:*******:** ****:*** .** **** :********:*:. :. *.* : .. :*:: .* .. : ", "identical_positions": 283, "similar_positions": 139, "identity": "46.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030116-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62991-1", "uniprot_id": "SCFD1_RAT", "id": "Q62991-1", "name": "Sec1 family domain-containing protein 1", "aln": "---MVGSKMAA--SIRERQTVALKRMLNFNVPHVKN-----------SPGEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIRDVPAVYFVMPTEENIDRLCQDLRNQLYESYYLNFISAISRSKLEDIANAALAANAVTQVAKVFDQYLNFITLEEDMFVLCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCSRGTAAEMVAVKLDKKLRENLRDARNSLFTGDP--LGTGQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESTGVENSPTGARPKRKNKKSYDLTPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTTLDKSLLDVISDPDAGTPEDKMRLFLIYYISAQQAPSEVDLEQYKKALTDAGCNLSPLQYIKQWKAFAKMA---STPASYGNTT-----------TKPMGLLSRVMNTGSQFVMEGVKNLVLKQQNLPVTRILDNLMEMKSNPE-----TDDYRYFDPKMLRSNDSSVPRNKSPFQEAIVFVVGGGNYIEYQNLVDYIKGKQG----KHILYGCSEIFNATQFIKQLSQLGQK--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BRF7-1", "uniprot_id": "SCFD1_MOUSE", "id": "Q8BRF7-1", "name": "Sec1 family domain-containing protein 1", "aln": "---MVGSKMAATASIRERQTVALKRMLNFNVPHVKN-----------STGEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIPDVPAVYFVMPTEENIDRLCQDLRNQLYESYYLNFISAISRSKLEDIANAALAASAVTQVAKVFDQYLNFITLEDDMFVLCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCSRGTAAEMVAVKLDKKLRENLRDARNSLFTGDP--LGTGQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESTGVENSPAGARPKRKNKKSYDLTPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTTLDKSLLDVISDPDAGTPEDKMRLFLIYYISAQQAPSEVDLEQYKKALTDAGCNLSPLQYIKQWKAFAKMA---STPASYGNTT-----------TKPMGLLSRVMNTGSQFVMEGVKNLVLKQQNLPVTRILDNLMEMKSNPE-----TDDYRYFDPKMLRSNDSSVPRNKSPFQEAIVFVVGGGNYIEYQNLVDYIKAKQG----KHILYGCSEIFNATQFIKQLSQLGQK--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WVM8-1", "uniprot_id": "SCFD1_HUMAN", "id": "Q8WVM8-1", "name": "Sec1 family domain-containing protein 1", "aln": "MAAAAAATAAAAASIRERQTVALKRMLNFNVPHIKN-----------STGEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIPDVPAVYFVMPTEENIDRMCQDLRNQLYESYYLNFISAISRSKLEDIANAALAASAVTQVAKVFDQYLNFITLEDDMFVLCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFFVTLGAVPIIRCSRGTAAEMVAVKLDKKLRENLRDARNSLFTGDT--LGAGQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESSGVENSPAGARPKRKNKKSYDLTPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTTLDKSLLDIISDPDAGTPEDKMRLFLIYYISTQQAPSEADLEQYKKALTDAGCNLNPLQYIKQWKAFTKMA---SAPASYGSTT-----------TKPMGLLSRVMNTGSQFVMEGVKNLVLKQQNLPVTRILDNLMEMKSNPE-----TDDYRYFDPKMLRGNDSSVPRNKNPFQEAIVFVVGGGNYIEYQNLVDYIKGKQG----KHILYGCSELFNATQFIKQLSQLGQK--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PC92-1", "uniprot_id": "A0A8M1PC92_DANRE", "id": "A0A8M1PC92-1", "name": "Sec1 family domain-containing protein 1", "aln": "--------MAA--SIREKQTAALKRMLNFNAPPLKN-----------TTAEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHSDRDPIPDVPAIYFIMPTEENIDRICQDLRNQLYESYYLNFISAISRSKLEDIASAALAANAVNQVTKVFDQYLNFITLEDDMFILCNQNKEHISYHAINKPDIMDTDMEGIMDTIVDSLFCFFVTLGAVPIIRCPRGNAAEMVAVKLDKKLRENLRDARNSLFTGDT--MGTGQFSFQRPLFVLADRNLDLATPLHHTWTYQALIHDVLDFHLNRVSVDESHGSEASPAGARPKKKNKKSYDLTAADKFWQKHKGSPFPEVAEAVQEELDTYRAQEDEVKRLKSIMGLEGEDDGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLDHIKSRKLDVYFEYEEKLMSKSTLDKSLLDIISDPDAGTAEDKMRLFLIYYITSQQPPLEADLEQYKKAMVDAGCDLSPLNYIKQWKAFTKMA---ATPANYGSSG-----------VKPMGLFSRVMNTGSQFVMEGVKNLVLKQHNLPVTRILDNLMEMKSNPE-----TDDYRYFDPKMLRGSESSIPRNKNPFQEAIVFVVGGGNYIEYQNLVDYTKTRQG----KRILYGCSELFNAAQFIKQLSQLGQK--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24179-1", "uniprot_id": "SLY1_DROME", "id": "Q24179-1", "name": "Protein sly1 homolog", "aln": "-----------MLTLRERQINAIKQMLNLNSQQPKA-----------LAAEPVWKILIYDRVGQDIISPIISIKELRELGVTLHVQLHSDRDSIPDVPAIYFCLPTDENLDRIQQDFSSGLYDVYHLNFLAPITRSKIENLAAAALHAGCVANIHRVYDQYVNFISLEDDFFILKHQQSDQLSYYAINRANTRDEEMEALMDSIVDSLFALFVTLGNVPIIRCPRNSAAEMVARKLEKKLRENLWDARANLFHMDATQAGGGVFSFQRPVLLLLDRNMDLATPLHHTWSYQALVHDVLDLGLNLVYVED----ETASAGAR---KKPKACDLDRNDRFWMTHKGSPFPTVAEAIQEELESYRNSEEEIKRLKTSMGIEGESDIAFSLVNDTTARLTNAVNSLPQLMEKKRLIDMHTKIATAILNFIKARRLDSFFEIEEKVMSKQTLDRPLLDLLRDGEFGQAEDKLRLYIIYFICAQQLP-ESEQERLKEALQAAGCDLTALAYVQRWKGIMNRSPSISQATQYEGGG-----------TKTVSMFTKLVSQGSSFVMEGVKNLVVKRHNLPVTKITEQVMECRSNAE-----TDDYLYLDPKLLKGGE-VLPKNRAPFQDAVVFMVGGGNYIEYQNLVDFIKQKQTSNVQRRIIYGASTLTNARQFLKELSALGGEIQSPTATS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22213-1", "uniprot_id": "SLY1_YEAST", "id": "P22213-1", "name": "Protein SLY1", "aln": "-MAVEEIASRKDISLRDMQISAILKMLFLNKDLNNNDNITTITDDIFNQQEIIWKVLILDIKSTATISSVLRVNDLLKAGITVHSLIKQDRSPLPDVPAIYFVSPTKENIDIIVNDLKSDKYSEFYINFTSSLPRNLLEDLAQQVSITGKSDKIKQVYDQYLDFIVTEPELFSLEISN----AYLTLNDPKTTEEEITGLCANIADGLFNTVLTINSIPIIRAAKGGPAEIIAEKLGTKLRDFVINTNSSSTSTLQ-----GNDSLERGVLIILDRNIDFASMFSHSWIYQCMVFDIFKLSRNTVTIPLES-KENGTDNTTAKPLATKKYDIEPNDFFWMENSHLPFPEAAENVEAALNTYKEEAAEITRKTGVTNISDLD----PNSNNDTVQIQEVVKKLPELTAKKNTIDTHMNIFAALLSQLESKSLDTFFEVEQDPGSTKTRSR-FLDILKDGKTNNLEDKLRSFIVLYLTSTTGLPKDFVQNVENYFKENDYDINALKYVYKLREFMQLSNMSLQNKSLEDGSDSAFKPSNLTLSGIYGLTEGKLQGGVGSLISGIKKLLPEKKTIPITNVVDAIMDPLNSSQKNLETTDSYLYIDPKITRGSHTRKPK-RQSYNKSLVFVVGGGNYLEYQNLQEWAHSQLHN--PKKVMYGSTAITTPAEFLNEISRLGASNSSNNDA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*: * *: :** :* : * :**:** * . **.:: :::* . *:*:* ::.**..: ****:** **.**:* : :*: . *. :::** :.:.*. :*::* . :. :: :*:***::** * ::* * .: :* ::* .. : :: : .*.*.** .:*:. :****..:. .**::* ** .***: : ::. . * *::* :::: ***:*:*: : *:* **.::.*::.: * * : * .. .: * *: * ** :. *** .** :: *::*: . *:.* . .:.. . . .: *.:: ..*..**:* **. ** * :: :*:*. :::: ** :** *:. *. * .: :**:: * . . ***:* ::: :: : : :. :: : . ::..* *: : : : : : . . .: :. * ::.*:*:*: :::.:*:*.: : :*: ...: **.* *:***: :... *: : .::.::**:******:***** :: : : ::::**.: : .. :*::::* ** . ", "identical_positions": 158, "similar_positions": 249, "identity": "23.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030121-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P40807-1", "uniprot_id": "DCOR1_DROME", "id": "P40807-1", "name": "Ornithine decarboxylase 1", "aln": "---------------------MAAATPEIQFYERELNIR----RVIEECDLQRL-----------------------------DQALNICDLSSVERKLRLWQKLLPRIKPFYAVKCNDDPMVVRLLAQLGAGFDCASKNEVKLVLGFDVSPERIIFANPCRPVSHLEYAKEHQVSNGTVDNEFEVYKLHTHYPNSNLIVRFKSEAKEAQCPLGDKFGCDADVDAAALMLLAKSLELKVTGTSFHVGSGCSELQAYDRAIKKAKNLFKFGALLG--YDMDFLDIGGGFPGSDDVKFEKIAESVNTSVQRHFPDER-VHIIAEPGRFFVAAACTLVCKIHAKREIRNEAGKL----------DTVMYYLNDGVYGSFNCILYDHQVVIA-------EHYLDNAESLP-------------HLKSLIWGPSCDALDKISEDLHLPN-LNRGDLLGFRNMGAYTMPIASAFNGFEVPKTLYFQAI---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40808-1", "uniprot_id": "DCOR2_DROME", "id": "P40808-1", "name": "Ornithine decarboxylase 2", "aln": "---------------------MVNGDLRIQYYDEELNIR----KVIEQADLEHL-----------------------------DQALNICDLSSLERKLRLWHKLMPRIEPHYAVKCNDDPVVVKFLADLGTGFDCASKNELKLVLGLGVSPERIIFAHPCRPASHLRYAKEQQVVNGTVDNEYEIYKLRKHYPDSNLIVRFKSEAKKALCPLGDKYGCDAEADAAALMLLAKALGLKVTGTSFHVGSGCSEVEAYDRAIEKAENIFKVGEMIG--HKMELLDVGGGFPGIDDEMFEEIAQSVNTSVELRFPDKR-IRIISEPGRFFVEAAYTLICKVHAKREVRSKDGKL----------DTMMYYLNDGIFGAFAGMFYYPEEVAP-------ELYLDEAESLP-------------KLKSVIWGPSCDAMDKIS-DLLLPN-LNPGDLLGFRNMGAYTMPIASPFNGFDVPETRFFKAK---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08432-1", "uniprot_id": "DCOR_YEAST", "id": "P08432-1", "name": "Ornithine decarboxylase", "aln": "MSSTQVGNALSSSTTTLVDLSNSTVTQKKQYYKDGETLHNLLLELKNNQDLELLPHEQAHPKIFQALKARIGRINNETCDPGEENSFFICDLGEVKRLFNNWVKELPRIKPFYAVKCNPDTKVLSLLAELGVNFDCASKVEIDRVLSMNISPDRIVYANPCKVASFIRYAASKNVMKSTFDNVEELHKIKKFHPESQLLLRIATDDSTAQCRLSTKYGCEMEN-VDVLLKAIKELGLNLAGVSFHVGSGASDFTSLYKAVRDARTVFDKAANEYGLPPLKILDVGGGFQ---FESFKESTAVLRLALEEFFPVGCGVDIIAEPGRYFVATAFTLASHVIAKRKLSENE---------------AMIYTNDGVYGNMNCILFDHQEPHPRTLYHNLEFHYDDFESTTAVLDSINKTRSEYPYKVSIWGPTCDGLDCIAKEYYMKHDVIVGDWFYFPALGAYTSSAATQFNGFEQTADIVYIDSELD------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "O14977-1", "uniprot_id": "AZIN1_HUMAN", "id": "O14977-1", "name": "Antizyme inhibitor 1", "aln": "-----------------MKGFIDDANYSVGLLDEGTNLG----NVIDNYVYEHT--------------------------LTGKNAFFVGDLGKIVKKHSQWQNVVAQIKPFYTVKCNSAPAVLEILAALGTGFACSSKNEMALVQELGVPPENIIYISPCKQVSQIKYAAKVGVNILTCDNEIELKKIARNHPNAKVLLHIATEDNIGGEEGNMKFGTTLKN-CRHLLECAKELDVQIIGVKFHVSSACKESQVYVHALSDARCVFDMAGEIG--FTMNMLDIGGGFTGT-EFQLEEVNHVISPLLDIYFPEGSGVKIISEPGSYYVSSAFTLAVNIIAKKVVENDKFPSGVEK-TGSDEPAFMYYMNDGVYGSFASKLSEDLNTIP-------EVHKK-YKEDEP------------LFTSSLWGPSCDELDQIVESCLLPE-LNVGDWLIFDNMGADSFHEPSAFNDFQRPAIYYMMSFSDWYEMQDAGITSDSMMKNFFFVPSCIQLSQEDSFSAEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63764-1", "uniprot_id": "AZIN1_RAT", "id": "Q63764-1", "name": "Antizyme inhibitor 1", "aln": "-----------------MKGFIDDANYSVGLLDEGTNLG----NVIDNYVYEHT--------------------------LTGKNAFFVGDLGKIVKKHSQWQNVVAQIKPFYMVKCNSTPAVLEILAALGTGFACSTKNEMALVQELGVSPENIIYTSPCKQASQIKYAAKVGVNIMTCDNEVELKKIARNHPNAKVLLHIATEDNIGGEDGNMKFGTTLKN-CRHLLECAKELDVQIIGVKFHISSACKEYQVYVHALSDARCVFDMAGEFG--FTMNMLDIGGGFTGT-EIQLEEVNHVISPLLDIYFPEGSGIQIISEPGSYYVSSAFTLAVNIIAKKVVENDKLSSGVEK-NGSDEPAFVYYMNDGVYGSFASKLSEDLNTVP-------EVHKK-YKEDEP------------LFTSSLWGPSCDELDQIVESCLLPE-LSVGDWLIFDNMGADSLHGPSAFSDTQRPAIYFMMSLSDWYEMQDAGITSDAMMKNFFFAPSCIQLSQEDNFSTEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q801V3-1", "uniprot_id": "Q801V3_DANRE", "id": "Q801V3-1", "name": "", "aln": "-----------------MKGFVDAPNYFIELLEGGTTLE----NVIDNHIYEQN--------------------------LAEKNAFVVADLGALMRQHVVWKTTMPLVRPFYPVSCNSSPVVIELLSALGVGFVCANKAETTLVLSHDVPPENIILSGVCKQLSLIKHAAKTGINFLLCENEAELRKIARAHPEAKLLLQVSTEAQI--EEASVTIGCSLKG-CRHLLELAKELNVSVAGVTFQVPASCKDPQAYTHALSDARCIFDMGKELG--FDMNILDIGGGFSGS-EFQLKQVHSVIRPLLEAYFPSESGVSIIAEPGNFFVFSCFTLAVNVIGKKAAYRNLHTSTHDKLTSSDAPEFVYYMNDGVYGSFMGRLFGNIISTP-------SVHKMSLTLDEP------------VFSSSLWGPSCDPLDQVVERCLLPE-LAVGDWLVFSNMGASGQEGPATFSDTDQPPVYYTISTDDWFEMQEAGISLDDTMKNLSLVQFGL------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABJ3HKJ7-1", "uniprot_id": "A0ABJ3HKJ7_MOUSE", "id": "A0ABJ3HKJ7-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPKKRRRF-----TRLFG-P----------LSHGELSDR----------------------VYNYPEG-LG---EVLYREQFDFN---------------AEPP------------------WEPS--------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ::. * * ..: : :* * : * *: ", "identical_positions": 7, "similar_positions": 11, "identity": "1.34%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030123-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2S5-1", "uniprot_id": "A0A0G2K2S5_RAT", "id": "A0A0G2K2S5-1", "name": "Dual specificity protein kinase TTK", "aln": "MEAEELIGRNLTIDSIMNKVRDIKNKIN-EDLTDELNSIKVCVDPT---ETVNQIMMVENTPENWLNFLLKLEKNSPPLND-ALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRLAELKAIQEPDDAH-DYFQMARENCKKFAFVHVSFAQFELSQGNLKKSEQLLHKAVETGAVPLQMLETAIRNLHLQKKQLLSEEDKKSLSAS---------------------TVLTAQESFSSSLGN-------LQSRKSSCDPKV------------------QAAAARILYGENMPPKDAEVSHRNPLKQTNKTKRSCPFGRVPVNLLN---SPDYY------VKTDGSAVPQFTKRKISGSE------------------------------YRDSIMPG---------------SKSSGNDSY--------ELRGLKP------------------------------------IQAIHLKDSLVSNEKSSELMS-DLVTLKSKTDSS-LTKLEVSEPKVRQEPEIPERRHKQWQSARKPGCGIQ-NSAAFAPQWHVPDVTPK-ADKEQKCTTVEQLAFSVSKQSPPLSVPKWIDPKSVCETPSSSSLDDYMKCFKTSVVKN-EFPPACPSSTPYSQLARHQQHQQQGLSTPLQNLQISGSSSMSECISVNGRIYSILKQIGSGGSSKVFQVLNEKKQINAIKYVNLEDADSQTIDSYRNEIAYLNKLQQHSDKIIRLYDYEIT--DRYIYMVMECGNIDLNSWLKKKKS--INPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSIVKDSQVGTVNYMAPEAIRDMSSS----RENGKIKTKISPRSDVWSLGCILYYMTYGKTPFQHIINQVSKLHAIIDPSHEIEFPEISEKDLRDVLKCCLVRNPKERISIPELLAHPYVQIQPHPGSQMAKETTDEMKYMLGQLVCLNSPNSILKAAKTLYERYNCGESQAPSSSKTSDKKRERE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35761-1", "uniprot_id": "TTK_MOUSE", "id": "P35761-1", "name": "Dual specificity protein kinase TTK", "aln": "MEAEELIGSSVTIDSIMSKMRDIKNKIN-EDCTDELSLSKICADHT---ETVNQIMRVGNTPENWLNFLLKLEKNSSPLND-DLLNKLIGRYSQAIEVLPPDKYGQNESFARIQVRLAELKAIQEPDDAR-DYFQMARENCKKFAFVHVSFAQFELSQGNLKKSEQLLHKAVETGAVPLQMLETAMRNLHLQKKQLLPEEDKKSVSAS---------------------TVLSAQEPFSSSLGN-------VQNRSISCESRG------------------QAGAARVLYGENLPPQDAEVRHQNPFKQTHAAKRSCPFGRVPVNLLN---SPDFY------VKTDSSAVTQLTTRLALSSVPLPYVTCLLHLQLLA-----LAGLAKGSGPDRDAILPG---------------SRPRGSDSY--------ELRGLKP------------------------------------IQTIYLKDSLVSNEKSSELMS-DLIALKSKTDSS-LTKLEETKP------EIAERRPMQWQSTRKPECVFQ-NPAAFAPLRHVPDVTPK-ADKE----------------SPPISVPKWLDPKSACETPSSSSLDDYMKCFKTPVVKN-DFPPACPSSTPYSQLARLQQQQQQGLSTPLQSLQISGSSSINECISVNGRIYSILKQIGSGGSSKVFQVLNEKKQINAIKYVNLEDADSQTIESYRNEIAFLNKLQQHSDKIIRLYDYEIT--EQYIYMVMECGNIDLNSWLKKKKS--INPWERKSYWKNMLEAVHIIHQHGIVHSDLKPANFVIVDGMLKLIDFGIANQMQPDTTSIVKDSQVGTVNYMAPEAIRDMSSS----RENSKIRTKVSPRSDVWSLGCILYYMTYGRTPFQHIINQVSKLHAIINPAHEIEFPEISEKDLRDVLKCCLVRNPKERISIPELLTHPYVQIQPHPGSQMARGATDEMKYVLGQLVGLNSPNSILKTAKTLYERYNCGEGQDSSSSKTFDKKRERK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P33981-1", "uniprot_id": "TTK_HUMAN", "id": "P33981-1", "name": "Dual specificity protein kinase TTK", "aln": "MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSD-ALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDAR-DYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEMLEIALRNLNLQKKQLLSEEEKKNLSAS---------------------TVLTAQESFSGSLGH-------LQNRNNSCDSRG------------------QTTKARFLYGENMPPQDAEIGYRNSLRQTNKTKQSCPFGRVPVNLLN---SPDCD------VKTDDSVVPCFMKRQTSRSE------------------------------CRDLVVPG---------------SKPSGNDSC--------ELRNLKS------------------------------------VQNSHFKEPLVSDEKSSELIITDSITLKNKTESSLLAKLEETKEYQ--EPEVPESNQKQWQSKRKSECINQ-NPAASSNHWQIPELARK-VNTEQKHTTFEQPVFSVSKQSPPISTSKWFDPKSICKTPSSNTLDDYMSCFRTPVVKN-DFPPACQLSTPYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEIT--DQYIYMVMECGNIDLNSWLKKKKS--IDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSS----RENGKSKSKISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQTHPVNQMAKGTTEEMKYVLGQLVGLNSPNSILKAAKTLYEHYSGGESHNSSSSKTFEKKRGKK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AYG3-1", "uniprot_id": "TTK_DANRE", "id": "Q8AYG3-1", "name": "Dual specificity protein kinase Ttk", "aln": "MDEEESTERQMQIAMLCQKLAMMKQLFN-EDDTDYIN-----------------QAISSNSPDTCRTFLSNLEKKGNPQADPSLLSKLMDSYTRVFSSMPLGKYSQNESYAKMLVRFAELKAIQDVNDAQ-TSFDIARSHCKDFAFVHVAYAQFELLQGNMKKCTMILQKAFEMNAKPRHVLEAAVRNLKTGKRQLLSHEDKENLSVSALDHTQGSRRSDGTCELKPSNTFLHSDQKFSPQEENGPVWRTGSQHRRTAMAERVPMVPLSIPENETSDSDCAQKAEAPFTHSSGFSRQTSGSSVRSAFSLCSSKKGTPDGDSYSLNIKPPVISPDYLREDIEEGHTITALLNRAEKRETARTEETTDINQIISTNSTEGCQAFLKNLEKRADPHSDAAFLSKLLDCYSKVFARFPLAEHCKTESYARMLVRYAELKGIEDPEDAADDFSIARSHCKAFAFVHIAHAQFELSRGNSRKSVSILQKALSSNARPIELLQTAIRNLKSGKTLLLPAEHQESSEAEN--VEAQNGMKREENPVKAPEDHQKPFSKETSSEWKIPALITKHTSPEDRKAPVEPVSSSSSHHAVRTPAPLRLNPSLSCQTPNYRQPNP--NSFVTPVVKQRPVIVSVPATAQKMCPTALPCTPQSGVSYIQPPTQTPSSAFSNESITIKGKQFFIFKMIGRGGSSKVYQVFDHKKHVYAVKYVNLEEADAQAVESYKNEIEHLNHLQQYSDQIIKLYDYEIT--SSYIYMLMECGHLDLNTWLRNRKT--VKPLDRKAYWRNMLEAVHTIHKHGIVHSDLKPANFLIVDGSLKLIDFGIANQIQPDVTSIMKDSQVGTLNYMPPEAIKDTSS-------NGKPGSKISAKGDVWSLGCILYCMTYGKTPFQNITNQISKIHAIIDPSHEIDFPDIPEKDLLDVLKKCLVRNPRERISIAELLDHPYLQLQPQPAPEPAETSSSDFKRILNELVALQSPNSIARAASNLAMMCNSGRKLDVSECVKSSSQTLWK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KG66-1", "uniprot_id": "A0A0B4KG66_DROME", "id": "A0A0B4KG66-1", "name": "", "aln": "----------MTTPVPRRTKDMMALGLD------------------------------SDSEDDFNTPYRPRQAAAGERKQQPVASFQVQTRGKENEPHPLP-------INMLPRRVSELTMMDSDSDEE-DIKSNHNLNCAILNDSFVLSPSQELTNSNSN-----ITTRRTPSAAPLKQSDSNLSFLGRFNDMGINCSSQGSPVAN-------------------------SEKQVAKKTAP--------------------------------------TLQAAPSATERRPLQETETPLRNELPSTSKTKPDADFITPQVRTIG-------------------------------------------------------------------STLAG-------------------------------------------------------------------------------KSRSAVSNDFRAQKVLFQTPMTVSRAAPVA-----------------------------------------SDSISFSLCDTITE---------------------SPDIPEPPKKAEPPKSQHPSKKSLDH---VFRESDKDN------VPDKVDNVEPKELVSIPAVAVPPEQPSHKTSN------ILKIKNHEYTIDKKLGCGGSSSVFLARRSDSGNEFALKVVDLQADPQVVQGYLNETKLLAKLQGN-VCVVALYDYQLVREESKLYMVMEKGDCDLNKILQSYTTN-LPLYSLMNILYQMLQAVNYIHQHGVIHSDLKPANFLMVSGRLKLIDFGIASNIAVDSTSIIKFSQAGTFNYISPEALTDTSTGNSPMRRADQPKIKISTKSDVWSLGCILYLLLYQKTPFGHIRNVYAKMSAITTPGTSIEYPAIPP-----YYPIMLVHFTTVSALFADGQELPTVESQKAAVVHRTTTVPIPYDHSAAEPADTQQNRQQQLSTKAQLFISEMSKVKCLSHMCVYIFNSHFIVN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54199-1", "uniprot_id": "MPS1_YEAST", "id": "P54199-1", "name": "Serine/threonine-protein kinase MPS1", "aln": "------MSTNSFHDYVDLKSRTNTRQFS------------------------------DDEEFTTPPKLSNFGSALLSHTEKTSASEILSSHNNDKIANRLEEMDRSSSRSHPPPSMGNLTSGHTSTSSHSTLFGRYLRNNHQTSMTTMNTSDIEINVGNSLDKSFERIRNLRQNMKEDITAKYAER---RSKRFLISNRTTKLGPAKR---------------------AMTLTNIFDEDVPN---------------------------------------SPNQPINARETVELPLEDSHQTNFKETKRNTDYDSIDFGDLNPIQYIKKHNLP-------TSDLPLISQIYFDKQREEN-------------------------------RQAALRKHS------------------------------------------------------------------------SRELLYKSRSSSSSLSSNNLLANKDNSITSNNGSQPRRKVSTGSS--------SSKSSIEIRRALKENIDTSNNSNFNSPIHKIYKGISR-------------------NKDSDSEKREVLRNISINANHADNLLQQENKRLKRSLDDAITNENINSKNLEVFYHRPAPKPPVTKKVEIVEPAKSASLSNNRNIITVNDSQYEKIELLGRGGSSRVYKVKGSGNRVYALKRVSFDAFDDSSIDGFKGEIELLEKLKDQ-KRVIQLLDYEMG--DGLLYLIMECGDHDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPANFVLVKGILKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPPYGSFQGQN-RLLAIMNPDVKIPFPEHTSNN---------EKIPKSAIELMKACLYRNPDKRWTVDKVLSSTFLQPFMISGSIMEDLIRNAVRYGSEKPHISQDDLNDVVDTVLRKFADYKI-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : : . : . ..:*. . . . : : .. *: .* . . : : .. : . . :. : . :. . . .. . ::: :. : : . : : . . . : :.::. : : :* **** *: . . * * . ::.: .* * :*: :: * **:: . :*::** *. **. *.. . : :** .:: :*. *::*********::*.* **:******. : . ..: : :* ** **:.***: . *:. .*:** ***:* : * :.*: : . :: ** * .* :* . : . : . : : : : . . . : ", "identical_positions": 70, "similar_positions": 140, "identity": "6.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030124-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYT2-1", "uniprot_id": "NFE2_RAT", "id": "Q6AYT2-1", "name": "Transcription factor NF-E2 45 kDa subunit", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPCPPQPNRNRLP---QLPTGELG----------EMELTWQEIMSITELQGLNVPSEPSFEPQ-----APTPYPG--------------------PLPPPTYCPCSIHP----DAGFTLPPPPY---------------------ELPASTP--HAPDL-PYSYGNIAIP----------------------------------VSKP----LTLSGLLN---------------------------------------EPLPDPLALLDIGLPVGQP-------------------------------------------------------------------------------------KPQEDPESDSG---------LSLNYSDA--------------ESLELEG-----TEAGRRRSEYVDMYP-VEYPYSL-MPNSLAHPN--------YTLPPTETPLVLESS------------SGPVRAKPAVRGEAGSRDERRALAMKIPFPTDKIVNLPVDDFNELLAQYPLTESQLALVRDIRRRGKNKVAAQNCRKRKLETIVQLERELERLGSERERLLRARGEADRTLEVMRQQLTELYHDIFQHLRDESGNSYSPEEYVLQQAADGAIFLVPRGTKMEATD---------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07279-1", "uniprot_id": "NFE2_MOUSE", "id": "Q07279-1", "name": "Transcription factor NF-E2 45 kDa subunit", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPCPPQQNRNRLS---QLPVGELG----------EMELTWQEIMSITELQGLNVPSETSFEPQ-----APTPYPG--------------------PLPPPTYCPCSIHP----DAGFSLPPPSY---------------------ELPASTP--HVPEL-PYSYGNVAIP----------------------------------VSKP----LTLSGLLN---------------------------------------EPLPDHLALLDIGLPVGQP-------------------------------------------------------------------------------------KPQEDPESDSG---------LSLNYSDA--------------ESLELEG-----MEAGRRRSEYVDMYP-VEYPYSL-MPNSLAHPN--------YTLPPTETPLALESS------------SGPVRAKPAVRGEAGSRDERRALAMKIPFPTDKIVNLPVDDFNELLAQYPLTESQLALVRDIRRRGKNKVAAQNCRKRKLETIVQLERELERLSSERERLLRARGEADRTLEVMRQQLAELYHDIFQHLRDESGNSYSPEEYVLQQAADGAIFLVPRGTKMEATD---------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16621-1", "uniprot_id": "NFE2_HUMAN", "id": "Q16621-1", "name": "Transcription factor NF-E2 45 kDa subunit", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPCPPQQSRNRVI---QLSTSELG----------EMELTWQEIMSITELQGLNAPSEPSFEPQ-----APAPYLG--------------------PPPPTTYCPCSIHP----DSGFPLPPPPY---------------------ELPASTS--HVPDP-PYSYGNMAIP----------------------------------VSKP----LSLSGLLS---------------------------------------EPLQDPLALLDIGLPAGPP-------------------------------------------------------------------------------------KPQEDPESDSG---------LSLNYSDA--------------ESLELEG-----TEAGRRRSEYVEMYP-VEYPYSL-MPNSLAHSN--------YTLPAAETPLALEPS------------SGPVRAKPTARGEAGSRDERRALAMKIPFPTDKIVNLPVDDFNELLARYPLTESQLALVRDIRRRGKNKVAAQNCRKRKLETIVQLERELERLTNERERLLRARGEADRTLEVMRQQLTELYRDIFQHLRDESGNSYSPEEYALQQAADGTIFLVPRGTKMEATD---------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B990-1", "uniprot_id": "A0A8M2B990_DANRE", "id": "A0A8M2B990-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCSAVSGVLPLRISCEGLPNPGRLHGEVSMSTNVTGLRTHRSPQNLEMDLAWQELMAITELQEFEEPNENPFEAIPYLSMEPMVSQGGFGMN--------------QPQPESIPATCDAHPSGVYESAYPEMMPPYPH-----MDMHYGLAGGHGSSRMLANTQGFHPPLMSLLEHMNMTTRG-------------------------------HGIVKDGIINFHSTGQIK---------------------------------------QVCTDDLES-DSGLSLGSS-------------------------------------------------------------------------------------PPLASPENAVHGVPAYLPTDISTGYAES--------------ESIGEQCRLRPNLHGAVDYQQSYSSYPGASFPTSANMPSSNLHTYSPVASIKQPVLPTALHDLQLNSSRVGSY------QSPYPKCKSSSVPVPLSRDERRALALKIPFSLEKIVNLPVDDFNELLTQFTLNDAQLALVRDIRRRGKNKVAAQNCRKRKLENIVHLESELGQLRAQREHLARERLEFQQNIAIIKCRLSDLHTQVFSQLHDEEGHPYSVDEYSLQQTNDGNIYLVPRNAALAGE----------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20482-1", "uniprot_id": "CNC_DROME", "id": "P20482-1", "name": "Segmentation protein cap'n'collar", "aln": "MISNKKSYAMKMLQLALALSLLHYNPDYLLHRWDSQLELGTHGDGWELEMLRTVHRLDMDHNPYGNRKGLSPRIEDLLNFDDPSLGGMANGIGGCKLPPRFNGSTFVMNLHNTTGNSSVQTAALQDVQSTSAAATGGTMVVGTGGAPTSGGQTSGSALGEIHIDTASLDPGNANHSPLHPTSELDTFLTPHALQDQRSIWEQNLADLYDYNDLSLQTSPYANLPLKDGQPQPSNSSHLDLSLAALLHGFTGGSGAPLSTAALNDSTPHPRNLGSVTNNSAGRSDDGEESLYLGRLFGEDEDEDYEGELIGGVANACEVEGLTTDEPFGSNCFANEVEIGDDEEESEIAEVLYKQDVDLGFSLDQEAIINASYASGNSAATNVKSKPEDETKSSDPSISESSGFKDTDVNAENEASAASVDDIEKLKALEELQQDKDKNNENQLEDITNEWNGIPFTIDNETGEYIRLPLDELLNDVLKLSEFPLQDDLSNDPVASTSQAAAAFNENQAQRIVSETGEDLLSGEGISSKQNRNEAKNKDNDPEKADGDSFSVSDFEELQNSVGSPLFDLDEDAKKELDEMLQSAVPSYHHPHPHHGHPHAHPHSHHHASMHHAHAHHAAAAAAAHQRAVQQANYGGGVGVGVGVGVGVGSGTGSAFQRQPAAGGFHHGHHQGRMPRLNRSVSMERLQDFATYFSPIPSMVGGVSDMSPYPHHYPGYSYQASPSNGAPGTPGQHGQYGSGANATLQPPPPPPPPHHAAMLHHPNAALGDICPTGQPHYGHNLGSAVTSSMHLTNSSHEADGAAAAAAAYKVEHDLMYYGNTSSDINQTDGFINSIFTDEDLHLMDMNESFCRMVDNSTSNNSSVLGLPSSGHVSNGSGSSAQLGAGNPHGNQANGASGGVGSMSGSAVGAGATGMTADLLASGGAGAQGGADRLDASSDSAVSSMGSERVPSLSDGEWGEGSDSAQDYHQGKYGGPYDFSYNNNSRLSTATRQPPVAQKKHQLYGKRDPHKQTPSALPPTAPPAAATAVQSQSIKYEYDAGYASSGMASGGISEPGAMGPALSKDYHHHQPYGMGASGSAFSGDYTVRPSPRTSQDLVQLNHTYSLPQGSGSLPRPQARDKKPLVATKTASKGASAGNSSSVGGNSSNLEEEHLTRDEKRARSLNIPISVPDIINLPMDEFNERLSKYDLSENQLSLIRDIRRRGKNKVAAQNCRKRKLDQILTLEDEVNAVVKRKTQLNQDRDHLESERKRISNKFAMLHRHVFQYLRDPEGNPCSPADYSLQQAADGSVYLLPREKSEGNNTATAASNAVSSASGGSLNGHVPTQAPMHSHQSHGMQAQHVVGGMSQQQQQQSRLPPHLQQQHHLQSQQQQPGGQQQQQHRKE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . :: :. : ::. * : . * * * . .. ** . * * * : : : * : : : :* :. * * . * * * * . .*:.: :: : . . *. * : . *. * : * .: * .. :***:** :::**:. .*:***:*:*** *::: *.: **:*:*********************: *: ** *: : .: :* : * . : : ::: *: .:*. *:* .*:. * :* ***: ** ::*:** ", "identical_positions": 86, "similar_positions": 91, "identity": "6.22%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030128-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P02686-1", "uniprot_id": "MBP_HUMAN", "id": "P02686-1", "name": "Myelin basic protein", "aln": "MGNHAGKRELNAEKASTNSETNRGESEKKRNLGELSRTTSEDNEVFGEADANQNNGTSSQDTAVTDSKRTADPKNAWQDAHPADPGSRPHLIRLFSRDAPGREDNTFKDRPSESDELQTIQEDSAATSESLDVMASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFGGDRGAPK-RGSGKDSHHPARTAHYGSLPQKS-HGRTQDENPVVHFFKNIVTPRTPPPSQGKGRGLSLSRFSWGAEGQRPGFGYGGRASDYKSAHKGFKGVDAQGTLSKIFKLGGRDSRSGSPMARR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04370-1", "uniprot_id": "MBP_MOUSE", "id": "P04370-1", "name": "Myelin basic protein", "aln": "MGNHSGKRELSAEKASKDGEIHRGEAGKKRSVGKLSQTASEDSDVFGEADAIQNNGTSAEDTAVTDSKHTADPKNNWQGAHPADPGNRPHLIRLFSRDAPGREDNTFKDRPSESDELQTIQEDPTAASGGLDVMASQKRPSQR--SKYLATASTMDHARHGFLPRHRDTGILDSIGRFFSGDRGAPK-RGSGKDSHT--RTTHYGSLPQKSQHGRTQDENPVVHFFKNIVTPRTPPPSQGKG---------------------------------------------------GRDSRSGSPMARR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "I3ITP3-1", "uniprot_id": "I3ITP3_DANRE", "id": "I3ITP3-1", "name": "Myelin basic protein", "aln": "-----------MATASTSGQNPFGLGRKKKAPGVLDQIS-----------------------------------------------------RFFGGDKKRKGKGSFRGHLS----------------------SSPQRPHHS---------------------STRRRGDVNPVVHFFRSFVSSPRPKSRWRELLGLASPSARGSESIRSPQRRRREQNTLSRIFNLGESRSRSPPK-----------------------------------------------------------RWSTIF---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .**...: * . **: * *.: : *:*. * : ..:*:.: * :* :** : * * ::.: :** . .:*: :. :: .: ** . :* : * :::*.: ::*: : .**. * .: : ", "identical_positions": 29, "similar_positions": 54, "identity": "9.48%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1001", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PB51-1", "uniprot_id": "CC117_MOUSE", "id": "Q6PB51-1", "name": "Coiled-coil domain-containing protein 117", "aln": "MAALGRPFSGLPLSGSADFLQPP-PAFAGRAFPPGAAGHDLAPRPGV-RGAPSSPGGRTARGRVSIHCRKKHKRLAE-DDECPVRKKRLTEAELGAVTD---EWALGAHQGREGHGVNTCPSSLS-MPSMLDVVCEEMDQTTGEP---------QCEVARRRLQEIEDRIIDEDEEVESDRNVS---HLPSLVLSDTMKTGLKREFDEVFTKRMIESMSRPSMELVLWKPLPELLPEKPKPSSSPKNYRRESQAKHAAPGTAFPQRTEGLLEPQCADAPLYRSLEAATSTEEEMEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IWD4-1", "uniprot_id": "CC117_HUMAN", "id": "Q8IWD4-1", "name": "Coiled-coil domain-containing protein 117", "aln": "MAALGRPFSGLPLSGGSDFLQPPQPAFPGRAFPPGADGAELAPRPGP-RAVPSSPAGSAARGRVSVHCKKKHKREEEEDDDCPVRKKRITEAELCAGPN---DWILCAHQDVEGHGVNPSVSGLS-IPGILDVICEEMDQTTGEP---------QCEVARRKLQEIEDRIIDEDEEVEADRNVN---HLPSLVLSDTMKTGLKREFDEVFTKKMIESMSRPSMELVLWKPLPELLSDKPKPSSNTKNYTGESQAKHVAAGTAFPQRTELFSEPRPTGMSLYNSLETATSTEEEMEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F2Z4X0-1", "uniprot_id": "F2Z4X0_DANRE", "id": "F2Z4X0-1", "name": "", "aln": "MQSSRSGTSELDF-----IMFSPHAHFS---------NPDLVPVSGPTKGLHHLTGGSMPNTSWERRCMRKQRRRTDDESCSPKRRKLMGEEGANQCPSPKASHIWPVDSPAPSPSSETSLVQLQTRPGMEEINLPFTAAPTPLPRVPSEGSGMEVEAAQRRLQEIEERITLEDDSDEEELDVEPAQRRPVLVMSDSLREGLQRGIGDILPHMVAQSVSRSCMELVVWRPPEDPLTQRLKDSLQRQQRKSRQTPTPVPSVSSPPSHQQTFS-------PLFS-----NSGEEDMEL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : * * : :: .* . *. . :*.* .* :. ..* .. . :* :*::* : :. .* *:* : * .. . ... . . :.. *. *.: :: .* * : *.*:*:*****:** **:. * : :*. : * **:**::: **:* :.:::.: : :*:**..****:*:* : *.:: * * . :: .. .. ... :: *.: : : .*: .* **:***", "identical_positions": 62, "similar_positions": 99, "identity": "20.95%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-10056", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q86XA0-1", "uniprot_id": "MET23_HUMAN", "id": "Q86XA0-1", "name": "Histone-arginine methyltransferase METTL23", "aln": "---------------------------------------------------------------MYVWPCAVVLAQYLWFHRRSLPGKAILEIGAGVSLPGILAAKCGAEVILSDSSELPHCLEVCRQSCQMNNLPHLQVVGLTWGHISWDLLALPPQDIILASDVFFEPEDFEDILATIYFLMHKNPKVQLWSTYQVRSADWSLEALLYKWDMKCVHIPLESFDADKEDIAESTLPGRHTVEMLVISFAKDSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2AA28-1", "uniprot_id": "MET23_MOUSE", "id": "A2AA28-1", "name": "Histone-arginine methyltransferase METTL23", "aln": "MDSVRPRAPWAPPPDPASLDSPTCEPGLMAGTQLFRFREEPVPGGNRAVLEVRVPQVLHVQYGMYVWPCAVVLAQYLWFHRRSLPGKAVLEVGAGVSLPGILAAKCGAKVILSDSSEFPHCLDICRQSCQMNNLPQVEVVGLTWGHISKDILSLPPQDIILGSDVFFEPEDFESILATVYFLMQKNPKVQFWSTYQVRSADWSLEGLLYKWDMKCVHIPLESFDADKEDIAESTLPGRHTVEMLIISFAKDSF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IMW2-1", "uniprot_id": "A0A0R4IMW2_DANRE", "id": "A0A0R4IMW2-1", "name": "", "aln": "----------------------MSELSQTLIVKTFTFEG----SGNTRSLTVSVPEVLDPQYGMYVWPSAVVLSQYVWMAREELQNKMVLELGAGVSLPGVVSALCGAAVILSDSAELPLCLENCRRSCVLNNLSHVHVLGLTWGRASPELLSLPPLDLILGSDVFYEPEDFEDVLVTVSFILRRNPHAQFWTTYQERSADWSIEALLHKWDLKCINVPLETFEANKTHLAGSTLPGNHTVQMMIITNNRI--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****.****:**:*: *..* .* :**:********:::* *** ******:*:* **: **:** :***.::.*:*****: * ::*:*** *:**.****:******.:*.*: *::::**:.*:*:*** ******:*.**:***:**:::***:*:*:* .:* *****.***:*::*: : ", "identical_positions": 111, "similar_positions": 59, "identity": "43.87%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1007", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P13861-1", "uniprot_id": "KAP2_HUMAN", "id": "P13861-1", "name": "cAMP-dependent protein kinase type II-alpha regulatory subunit", "aln": "MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLGHPPPEPGPDRVADAKGDSESEEDE-DLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYIIESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSSVDLGNLGQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A9C3T0-1", "uniprot_id": "A9C3T0_DANRE", "id": "A9C3T0-1", "name": "cAMP-dependent protein kinase type II-alpha regulatory subunit", "aln": "MS-IEIPVGLTELLQGYTVEVLRQRPPDLVEFAVQYFTRLRDTRSQDGSGAAAKTG---GKGVMFDGEPMQTESNGDEDDEDDDSDFEPPPPSRFNRRVSVCAEAFNPDDDEEDSEPRVVHPKTDEQRCRLQEACKDILLFKALDQEQFSEVLDAMFEVLVQPQDHVIDQGDDGDNFYVIERGVYDIVVQKDGVGCCVGQYNNKGSFGELALMYNTPRAATIIAKDEGALWGLDRATFRRLIVKNNAKKRRMYECFIESIPLLKSLELSERMKIVDVLGVKTFQDGERIIMQGDKADCFYIVESGEVKIMMKSKTKADRQD-NAEVEIARCSRGQYFGELALVTNKPRAASAYAIGDVKCLVIDIQAFERLLGPCKEIMKRNIAHYEEQLVALFGSSVDLRD---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *:** ****************:*********:******::*: . .**.. *: * ::::**.:.*:*: *:* * *************::***::***::***:********************** *****:*:******* :*:.::******************.***:* **. .****:*:******************:*..**:******.****:*********:*:*.****:*******:*********:* * ::****** **:***.***:*****.*:::*:**::::. * ******* :*********************:*******:*:********** :******:******* :******* : ", "identical_positions": 289, "similar_positions": 76, "identity": "71.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1008", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N878-1", "uniprot_id": "FRMD1_HUMAN", "id": "Q8N878-1", "name": "FERM domain-containing protein 1", "aln": "MAVPPRGRGIDPARTNPDTFPPSGARCMEPSPERPACSQQEPTLGMDAMASEHRDVLVLLPSREQ---LRLAVGVKATGRELFQQVCNVASIR---DAQFFGLCVVRNNEYIFMDLEQKLSKYFSKDWKKER-NEGNEKPRAPFVAFLRVQHYVENGRVISDHRARHLYYCHLKERVLRSQCA--HREEAYFLLAACALQADLGEHRE-------------SAHAG---RYFEPHSYFP-------------------------------------------QWIITKRGIDYILRHMPTLHRERQGLSPKEAMLCFIQEACRLEDVP-VHFFRLHKDKKE-GRPTVILGLALRGVHIYQ--------------------------GKKLEIQLDGLPAAQKLVYYTGCTWRSRHLLHLLRASHQLHLRVRPTLQQLRQREE--AEEKQHYRESYISDELELD---------LASRSFPGSGVSSQHCPHCLS--------------RHSADSHGSSYTSGIKANSWLR----ESREMSVDVPLEVHGLHEKEPSSSPRTSRSHPSTRGDSQATRQEPCTQVRTRGQSAEAVHQIQEMTAG--------------------------VSEEQHSHGLDDM-QLHQLALHP------------APTS--LSHTFHRALDCRLAGPCETRATLPSKRSSNCLALDLFGEAPPQEFVV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AZA5-1", "uniprot_id": "A0A8M3AZA5_DANRE", "id": "A0A8M3AZA5-1", "name": "", "aln": "MSVP---------------------------------TKQE------------RTVCVLLPNKET---LDITVGVKATGQDVFHRVCELLGVR---ELHYFGLTLVKNNEHIFLDLEEKLAKYFPKEWKQDSGKQGSHRRSIPPLLCLKVQYYVENGRLICERKARKLYYYDLRERVLRSECR--QQEEVYFQLAGFALQADHSDHSS-------------EGQSHGHAMYFQPKEYFP-------------------------------------------PWIIAKRGIDYLLCHGPKVHKELWGMSCRDAVLLFIRESCRLEDVP-VTFYRLQKDKKE-EKGSALLGLTLRGMQVFQEV---NNVRDLLYDFPWFHVGRLTFLGKKFEIQPDGLPSARKLVYYTGSAFRSRHLLLHLSSCHRLYLSLQPALKHLRQLEE--TEEKKRYRESYISDELDLDQPCSEGSPRLSRHSTSSSGIEADTRQNSVSVE-------MVSVEEKEKSSINTSSTAQSHEEHWQETDSQEPGEVSVDDPVDLLRLAELLEGVS-VDCPTIQSVKDSKDQHMSSVTGKDQTDLSDPDGLKQVLNQKLS--------------------------NPSDCYNLSLEDVRQLSPLLPLG------------TPTAPNASIGYTFALPHSPTNPCPDDTSLCVQRPTNCLSLARLDDNQPLELVL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q07436-1", "uniprot_id": "EXPA_DROME", "id": "Q07436-1", "name": "Protein expanded", "aln": "MRAFCTVS----------------------------APLEVCASSAEQLSPGSRFLALRLLGQQQPKTLYFLVDAKSRVREVYTQTCLHFATQGMLDTELFGLAVLIDGEYMFADPESKLSKYGPKSWRSSHTHGLDANGRPLLELHFRVQFYIESPFMLKDETSRHNYYLQLRHNILQRDLPREQAEQALVFLAGLALQADLGDAPPGTSNSKDDSGEETSASPSNGGRGLSATTTLPKISKRANERMLRLSTYVASTSKRETIPLPPSLPPNGADYYRIEDYLPSGLHTPWARSAMRACHREHLGMATAEAELLYIQQACSLHETINAHTYRMRLAKSEQGSGSAWFVVYAKGIKILGGESTNSSSNPETTTFLWPNITKLSFERKKFEIR----SGESRITLYAASDEKNKLLLTLCKDTHQWSMKLAARLKEVSKREEEEAAESQRLHASYACSRSLLLPYKSKNEQRISVISSTSSNTTSGIVSDRVHSEDELEIMINTPPAPLAAPSTESLALAHLLDRPSVSRQTSSVGQMSLKDLEEQLAALSVRPQDASSNGATIVTNSSVQRNSMGTTANDSSTATDSPSSQHNIGSQCSSTCSTVVVTSPVNGAGASSSGAPIPVHSTSSSLELGFSHTAQNSALSETSPDDFLSTSAREETESVSGASGVYTLAHGAPPTETSGVYTMHSSELTGQSSEIAESEKSSHYGMFQPQKLEETHVQHSDSVDGKKKEDFRPRSDSNVSTGSSFRGDGSDPTDNKHSLLSAEELTNLIVGRGTYPSRKTVSSSLHSDCDYVTLPLGDQGEEEVDQPPAPPPPYSARHEKTGLCGPPIAKPIPKPIAVVAPKPDSPPCSPPVPPAPIPAPPPAIRRRDPPPYSISSKPRPTSLISVSSSAHPAPSAAGSMSSLKSEEVTARFITTRPQISILKAHTSLIPDGAKPSYAAPHHCSSVASSNGSVCSHQLSQQSLHNSNYAGGSQASLHHHHVPSHHRHSGSAAIGIVPYGLHKSTASLHHQQSCVLLPVIKPRQFLAPPPPSLPRQPPPPPPPNHPHLASHLYEREMARKQLELYQQQLYSDVDYVIYPIQDPAVSQQEYLDAKQGSLLAAMAQAAPPPPHHPYLAMQVSPAIYRSTPYLPLTLSTHSRYASTQNLSDTYVQLPGPGYSPLYSPSMASLCSSYEPPPPPPLHPAALAAAAAAGAGSSSSSMFARSRSDDNILNSLDLLPKGKRLPPPPPPPYVNRRLKKPPMPAPSEKPPPIPSKPIPSRMSPIPPRKPPTLNPHHANSPLTKTSSGAQWAGERPRPDLGLGLGLNRGNNSILAQLQASMVAQSHAQAQAQALDIALLREKSKHLDLPLISALCNDRSLLKQTKVVINPKTGQEMPTSSAQPSGATTNGVANSSAGAGTLSKARKGSTVSHRHPQDKLPPLPVQQLAEANNYVIDPAVMMKQQQQQQQHNKTS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . : * : : * .:: * : *..*: :::: :.* . : : . *** :: :.*::* * *.**:** .*.*:.. : . . ::**.*:*. :: :. :*: ** .*:..:*: : : *:. . **. ***** .: .. . :.. :* :: : : *:* *:: :* * :*:::* *.:. . :*:: *.* :. : : :*::: **:**: .. ::. *:.. :.: ** *: : : . *:.: : ** : *.:: : ** ... * :: * ..*. : . : * : : . . ::*:. : . : : : . . . * ..... ::: . . ... . .:.. * * : : * : * : .. : : . :. : . :. ", "identical_positions": 74, "similar_positions": 184, "identity": "5.07%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-10106", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NP84-1", "uniprot_id": "TNR12_HUMAN", "id": "Q9NP84-1", "name": "Tumor necrosis factor receptor superfamily member 12A", "aln": "MARGSLRRLLRLLVLGLWLALLRSVAGEQAPGTAPCSRGSSWSADLDKCMDCASCRARPHSDFCLGCAAAPPAP-FRLLWPILGGALSLTFVLGLLSGFLVWRRCRRREKFTTPIEETGGEGCPAVALIQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QN02-1", "uniprot_id": "A0A8M9QN02_DANRE", "id": "A0A8M9QN02-1", "name": "", "aln": "MDSSATLRCLYWISL-VFATLINGINADKS--SALCAKSEFWNNDAAVCVPCYECKQYPKIPSCDTCPPIEPSDSWRVAAITSLSVLAAVIVFGALLIGVLVHQCRSRRTLRDPIEETTG---PLYAV--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .: * * : * :: :*:..: .::: :* *::.. *. * *: * .*: *: * *.. *: :*: ..*: .:*:* * :: ::** *..: ***** * * *: ", "identical_positions": 32, "similar_positions": 43, "identity": "24.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1016", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LPV0-1", "uniprot_id": "F1LPV0_RAT", "id": "F1LPV0-1", "name": "Asparagine--tRNA ligase, cytoplasmic", "aln": "-----------------------------------MSSEVIR---------GTADMVLAELYVSDREGNDA-TGDGTKEKPFKTGLKALMTVGKEP---FPTIYVDSQ--KENERWDVISKSQMKNIKK---MWHREQMKSDSREKKEAEDNLRREKNLEEAKKIIIKNDPSLPEPACVKISALEGYRGQRVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLSDDLCQCYNGVVLSTESSVAVYGTLNLTPKGKQAPGGHELSCDFWELVGLAPAGGADNLIN---EESDVDVQLNNRHMMIRGENMSKILKARSMITRCFRDHFFDRGYCEVTTPTLVQTQVEGGATLFKLDYFGEEAFLTQSSQLYLETCLPALGDVFCIAQSYRAEQSRTRRHLAEFTHVEAECPFLTFEDLLSRLEDLVCDVVDRVLKSPVA-SIVYDLNPNFKAPKRPFRRMNYSDAIEWLREHDVKKEDGTFYEFGDDIPEAPERLMTDTINEPILLCRFPVEIKSFYMQRCPEDPRLTESVDVLMPNVGEIVGGSMRSWDSEEILEGYKREGIDPAPYYWYTDQRKYGTCPHGGYGLGLERFLSWILNRYHIRDVCLYPRFLQRCRP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BP47-1", "uniprot_id": "SYNC_MOUSE", "id": "Q8BP47-1", "name": "Asparagine--tRNA ligase, cytoplasmic", "aln": "-----------------------------------MSSEVIR---------GTAEMVLAELYVSDREGNDA-TGDGTKEKPFKTGLKALMTVGKEP---FPTIYVDSQ--KENERWDVISKSQMKNIKK---MWHREQMKNDSREKKEAEDNLRREKNLEEAKKIIIKNDPSLPEPACVKISALEGYRGQRVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLSDDLCQCYNGVVLSTESSVAVYGTLNLTPKGKQAPGGHELSCDFWELVGLAPAGGADNLIN---EESDVDVQLNNRHMMIRGENMSKILKARSMITRCFRDHFFDRGYCEVTTPTLVQTQVEGGATLFKLDYFGEEAFLTQSSQLYLETCLPALGDVFCIAQSYRAEQSRTRRHLAEFTHVEAECPFLTFEDLLNRLEDLVCDVVDRVLKSPVA-SIVYELNPNFKPPKRPFRRMNYSDAIEWLKEHDVKKEDGTFYEFGDDIPEAPERLMTDTINEPILLCRFPVEIKSFYMQRCPEDPRLTESVDVLMPNVGEIVGGSMRSWDSEEILEGYKREGIDPAPYYWYTDQRKYGTCPHGGYGLGLERFLSWILNRYHIRDVCLYPRFLQRCRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43776-1", "uniprot_id": "SYNC_HUMAN", "id": "O43776-1", "name": "Asparagine--tRNA ligase, cytoplasmic", "aln": "-------------------------------------------------------MVLAELYVSDREGSDA-TGDGTKEKPFKTGLKALMTVGKEP---FPTIYVDSQ--KENERWNVISKSQLKNIKK---MWHREQMKSESREKKEAEDSLRREKNLEEAKKITIKNDPSLPEPKCVKIGALEGYRGQRVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLADELCQCYNGVLLSTESSVAVYGMLNLTPKGKQAPGGHELSCDFWELIGLAPAGGADNLIN---EESDVDVQLNNRHMMIRGENMSKILKARSMVTRCFRDHFFDRGYYEVTPPTLVQTQVEGGATLFKLDYFGEEAFLTQSSQLYLETCLPALGDVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFLTFDDLLNRLEDLVCDVVDRILKSPAG-SIVHELNPNFQPPKRPFKRMNYSDAIVWLKEHDVKKEDGTFYEFGEDIPEAPERLMTDTINEPILLCRFPVEIKSFYMQRCPEDSRLTESVDVLMPNVGEIVGGSMRIFDSEEILAGYKREGIDPTPYYWYTDQRKYGTCPHGGYGLGLERFLTWILNRYHIRDVCLYPRFVQRCTP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TDX3-1", "uniprot_id": "A0A8N7TDX3_DANRE", "id": "A0A8N7TDX3-1", "name": "Asparagine--tRNA ligase, cytoplasmic", "aln": "MRPHQLVCVCVECQEARRTNRFNGAFTVINSRRTEPDSTPLRSTECNMADEGVGKMSIKELYVSDKQGSDA-DGDGSEQKPFKTPLKALLFAGKEP---FPVIYVDSQ--KEGERWTVISKTQMKNTKK---AFHREQMKNESKDKKEAEDAERREKNLEEAKKITIENDSSLPEPKTVKIDKLEALREQRVKVFGWVHRLRRQGKNLLFIVLRDGTGFLQCVLTDKLCQCYNGLVLSTESSVALYGTVKPVPEGKQAPGGHELHCDFWELVGLAPAGGADNLLN---EESDVDVQLNNRHMMIRGENVSKILKVRSAVTQCFRDHFFSRGYCEITPPTLVQTQVEGGSTLFGLNYFGENAYLTQSSQLYLETCIPALGDTFCIAQSYRAEQSRTRRHLSEYTHIEAECPFMSYEDLLNRLEDLVCDVVDRVLKSPAA-PLLYDINPDFKPPKRPFKRMNYTEAIDWLKEHNIKKDDGTFYEFGEDIPEAPERLMTDSINETILLCRFPAEIKSFYMQRCPEDRRLTESVDVLMPNVGEIVGGSMRIWDSDELLEGYKREGIDPTPYYWYTDQRKFGTCPHGGYGLGLERFLTWLLNRHHIRDVCLYPRFIQRCRP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V434-1", "uniprot_id": "Q9V434_DROME", "id": "Q9V434-1", "name": "Asparagine--tRNA ligase, cytoplasmic", "aln": "-----------------------------------MPADQLA------------ELTLGAIFTSEKKGSDE-SGDGSESKPFKTILQAMRHAGKEP---FPTIYVDTKDPNAAEPYEPAAKSQLKKIQK---LFVRESHKNADKLQREAEDAEKRQQNLEDARKVKISEDPSLPVARKIRIYEGTANRDSRVKVYGWVHRLRRQGKSLIFITLRDGTGFLQCVLNDQLCQTYDALTLSTESSVVLFGTLKLVPEGKTAPGGHELNVDYWELIGLAPPGGADAILN---EEAQPDVQLDNRHIMIRGENTSKVLKMRSVVTQAFRGHYEARGYNEVTPPTLVQTQVEGGSTLFKLKYFGEEAYLTQSSQLYLETCLPALGDVFTISQSYRAEQSRTRRHLAEYTHVEAECPFLTFDDLLDRLEDLVCDVVDRVLKSPWG-YLVKELNPDFKPPQKPFRRMNYEDAIKWLKENNVTKDDGTFYEFGEDIPEAPERKMTDTINEPIMLCRFPAEIKSFYMQRCKEDQRLTESVDVLLPNVGEIVGGSMRIYDSEELLKGYKREGIDPQPYYWYTDQRVYGTMPHGGYGLGLERFLCWLLNRYHIREVCLYPRFLDRCRP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38707-1", "uniprot_id": "SYNC_YEAST", "id": "P38707-1", "name": "Asparagine--tRNA ligase, cytoplasmic", "aln": "---------------------------------------------------------MSSLYIKEATGVDELTTAGSQDHPFKTPAYALFASQQKSDATEPKLFVFKT---EDNEYQEISASALKKARKGCDGLKKKAVKQKEQELKKQQKEAENAAKQLSALNITIKEDESLPAAIKTRIYDSYSKVGQRVKVSGWIHRLRSN-KKVIFVVLRDGSGFIQCVLSGDLALAQQTLDLTLESTVTLYGTIVKLPEGKTAPGGVELNVDYYEVVGLAP-GGEDSFTNKIAEGSDPSLLLDQRHLALRGDALSAVMKVRAALLKSVRRVYDEEHLTEVTPPCMVQTQVEGGSTLFKMNYYGEEAYLTQSSQLYLETCLASLGDVYTIQESFRAEKSHTRRHLSEYTHIEAELAFLTFDDLLQHIETLIVKSVQYVLEDPIAGPLVKQLNPNFKAPKAPFMRLQYKDAITWLNEHDIKNEEGEDFKFGDDIAEAAERKMTDTIGVPIFLTRFPVEIKSFYMKRCSDDPRVTESVDVLMPNVGEITGGSMRIDDMDELMAGFKREGIDTDAYYWFIDQRKYGTCPHGGYGIGTERILAWLCDRFTVRDCSLYPRFSGRCKP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: .: * * *::.:**** *: ::. * ::* . : : : : :*: :* :: *. .: :: :. .. : .* :: *.:* *** . :* . .**** **:**** : *.::*:.****:*::**** ..*. : : *: **:*.::* : *:** **** ** *::*::**** ** * : * * :: .: *::**: :**: * ::* *: : :..* : . *:*.* :********:*** :.*:**:*:************:.:***.: * :*:***:*:*****:*:**:*** .*::::***.::* *: . *: :*:.* . :: ::**:*:.*: ** *::* :** **.*:::.:::* ::**:**.**.** ***:*. .*:* ***.*******:** :* *:*******:******.***** * :*:: *:******. .***: *** :** ******:* **:* *: :*. :*: .***** ** *", "identical_positions": 233, "similar_positions": 175, "identity": "37.82%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1024", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P501-1", "uniprot_id": "LAP4A_RAT", "id": "Q6P501-1", "name": "Lysosomal-associated transmembrane protein 4A", "aln": "------MVSMTFKRSRSDRFYSTRCCGCCHVRTGTIILGTWYMVVNLLMAILLTVEVTHPNSMPAVNIQYEVIGNYYSSERMADNACVLFAVSVLMFIISSMLVYGAISYQVGWLIPFFCYRLFDFVLSCLVAISSLTYLPRIKEYLDQLPDFPYKDDLLALDSSCLLFIVLVFFVVFIIFKAYLINCVWNCYKYINNRNVPEIAVYPAFEAPPQYVLPTYEMAVKIPEKEPPPPYLPA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60961-1", "uniprot_id": "LAP4A_MOUSE", "id": "Q60961-1", "name": "Lysosomal-associated transmembrane protein 4A", "aln": "------MVSMTFKRSRSDRFYSTRCCGCFHVRTGTIILGTWYMVVNLLMAILLTVEVTHPNSMPAVNIQYEVIGNYYSSERMADNACVLFAVSVLMFIISSMLVYGAISYQVGWLIPFFCYRLFDFVLSCLVAISSLTYLPRIKEYLDQLPDFPYKDDLLALDSSCLLFIVLVFFVVFIIFKAYLINCVWNCYKYINNRNVPEIAVYPAFETPPQYVLPTYEMAVKIPEKEPPPPYLPA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15012-1", "uniprot_id": "LAP4A_HUMAN", "id": "Q15012-1", "name": "Lysosomal-associated transmembrane protein 4A", "aln": "------MVSMSFKRNRSDRFYSTRCCGCCHVRTGTIILGTWYMVVNLLMAILLTVEVTHPNSMPAVNIQYEVIGNYYSSERMADNACVLFAVSVLMFIISSMLVYGAISYQVGWLIPFFCYRLFDFVLSCLVAISSLTYLPRIKEYLDQLPDFPYKDDLLALDSSCLLFIVLVFFALFIIFKAYLINCVWNCYKYINNRNVPEIAVYPAFEAPPQYVLPTYEMAVKMPEKEPPPPYLPA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5TYX5-1", "uniprot_id": "Q5TYX5_DANRE", "id": "Q5TYX5-1", "name": "Lysosomal-associated transmembrane protein 4A", "aln": "MFLQSTENDMRFKPSR-DRLYSARCCGCCHVRTGTIILGTWYMVVNLLMGILLTVAVTHPENVPTVDLQYEVIEHYFASDRMSENACVGFAISLLMLTISAMMVYGAITNRDGWLIPFFCYQLFDFALSCLVAISSLTYLPRIKDYLDQLPDFPYKDNLLSLDSSCLLLFVLIFFAILIVLKAYLINCVWNCYKYINNRNTPEIAVYPAFETPPQYILPTYEMAMTMPAKEPPPPYMPA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* ** .* **:**:***** ********************.***** ****:.:*:*::***** :*::*:**::**** **:*:**: **:*:*****: : *********:****.*****************:************:**:*******::**:**.::*::*******************.**********:****:*******:.:* *******:**", "identical_positions": 176, "similar_positions": 44, "identity": "73.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1028", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJQ4-1", "uniprot_id": "SIR2_RAT", "id": "Q5RJQ4-1", "name": "NAD-dependent protein deacetylase sirtuin-2", "aln": "-------------------------------------MDFLRNLFTQTLGLGSQK--------ERLLDELTLEGVTRYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYANLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFIRLLKEKGLLLRCYTQNIDTLERVAGLEPQDLVEAHGTFYTSHCVNTSCGKEYTMSWMKEKIFSEATP---KCEKCQNVVKPDIVFFGENLPPRFFSCMQSD-------------FSKVDLLIIMGTSLQVQPFASLISKAPLATPRLLINKEKTG-------QTDPFLGMMMGLGGGMDFDSKKAYRDVAWLGDCDQGC--LALADLLGWK-ELEDLVRREHANIDAQSGSQASNPSATVSPRKSPPPAKEAARTKEKEEH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDQ8-1", "uniprot_id": "SIR2_MOUSE", "id": "Q8VDQ8-1", "name": "NAD-dependent protein deacetylase sirtuin-2", "aln": "MAEPDPSDPLETQAGKVQEAQDSDSDTEGGATGGEAEMDFLRNLFTQTLGLGSQK--------ERLLDELTLEGVTRYMQSERCRKVICLVGAGISTSAGIPDFRSPSTGLYANLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFIRLLKEKGLLLRCYTQNIDTLERVAGLEPQDLVEAHGTFYTSHCVNTSCRKEYTMGWMKEKIFSEATP---RCEQCQSVVKPDIVFFGENLPSRFFSCMQSD-------------FSKVDLLIIMGTSLQVQPFASLISKAPLATPRLLINKEKTG-------QTDPFLGMMMGLGGGMDFDSKKAYRDVAWLGDCDQGC--LALADLLGWKKELEDLVRREHANIDAQSGSQAPNPSTTISPGKSPPPAKEAARTKEKEEQQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IXJ6-1", "uniprot_id": "SIR2_HUMAN", "id": "Q8IXJ6-1", "name": "NAD-dependent protein deacetylase sirtuin-2", "aln": "MAEPDPSHPLETQAGKVQEAQDSDSDSEGGAAGGEADMDFLRNLFSQTLSLGSQK--------ERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTP---KCEDCQSLVKPDIVFFGESLPARFFSCMQSD-------------FLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAG-------QSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGC--LALAELLGWKKELEDLVRREHASIDAQSGAGVPNPSTSASPKKSPPPAKDEARTTEREKPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVK3-1", "uniprot_id": "SIR2_DANRE", "id": "Q7ZVK3-1", "name": "NAD-dependent protein deacetylase sirtuin-2", "aln": "MSEEVSKRVEEEADTPGLEGQSDDSSDEGDASG-DTEMDFLRSLFSRTLGLSPG---------DKVLDELTLDSVARYILSGKCKNIICMVGAGISTSAGIPDFRSPGTGLYANLQKYNLPYPEAIFQIDYFKKHPEPFFALARELYPGQFKPTVYHYFIKMLKDKGLLRRCYSQNIDTLERVAGLEGEDLIEAHGTFHTSHCVSFLCRKEYSMDWMKNQIFSEEIP---KCDSCGSLVKPDIVFFGESLPSRFFTSMKAD-------------FPQCDLLIIMGTSLQVQPFASLVSRVSNRCPRLLINMEKTG-------QSEFGMGLFS-FGGGMDFDSDKAYRDVAHLSTCDDGC--MTLAELLGWKKELEEMVKREHALIDSKDAKKTDKEASQSS--KS---AVAEAEKTDKTE--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7I7-1", "uniprot_id": "SIRT2_DROME", "id": "Q9I7I7-1", "name": "NAD-dependent protein deacetylase Sirt2", "aln": "MGDIEVKK--EEQPTTPSNSSSSDDDEE----APDDTMDKVRRFFANTLHLGGSSDAKEEVKVEKVIPDLSFDGFAEHWRVHGFRKIVTMVGAGISTSAGIPDFRSPGSGLYSNLKKYELPHPTAIFDLDYFEKNPAPFFALAKELYPGSFIPTPAHYFIRLLNDKGLLQRHYTQNIDTLDRLTGLPEDKIIEAHGSFHTNHCIK--CRKEYDMDWMKAEIFADRLP---KCQKCQGVVKPDIVFFGENLPKRFYSSPEED-------------FQDCDLLIIMGTSLEVQPFASLVWRPGPRCIRLLINRDAVG-------QASCVL-FMDPNTRSLLFDKPNNTRDVAFLGDCDAGV--MALAKALGWDQELQQLITSERKKLSGSQNSEELQQGKEKP--QSDPDKMTSGDRDKKDASL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53686-1", "uniprot_id": "HST2_YEAST", "id": "P53686-1", "name": "NAD-dependent protein deacetylase HST2", "aln": "------------------------------------------------MSVSTAS------------TEMSVRKIAAHMKSNPNAKVIFMVGAGISTSCGIPDFRSPGTGLYHNLARLKLPYPEAVFDVDFFQSDPLPFYTLAKELYPGNFRPSKFHYLLKLFQDKDVLKRVYTQNIDTLERQAGVKDDLIIEAHGSFAHCHCIG--CGKVYPPQVFKSKLAEHPIKDFVKCDVCGELVKPAIVFFGEDLPDSFSETWLNDSEWLREKITTSGKHPQQPLVIVVGTSLAVYPFASLPEEIPRKVKRVLCNLETVGDFKANKRPTDLIVHQYSDEFAEQLVEELGWQEDFEKILTAQGGMGDNSKEQLLEIVHDLENLSLDQSEHESADKKDKKLQRLNGHDSDEDGASNSSSSQKAAKE---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. :::. .: : .:: :********.********.:*** ** : .**:* *:*::.:*:..* **::**:*****.* *: **:::::::*.:* * *:******:* :*: : ::****:* **: * : * :* :: . :*: * :*** ******.** * * . . *::::**** * ***** . *:* * : .* :. : .:. .*. : .: * : . * :*::: : .... : :. . : ", "identical_positions": 97, "similar_positions": 97, "identity": "22.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1030", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P36130-1", "uniprot_id": "CAF4_YEAST", "id": "P36130-1", "name": "CCR4-associated factor 4", "aln": "-------MGSGDTRGESSLVAKPIEIILNKLPHAILAQQQFQKYITSPIYRYLSKLLLFREVAWPESTKDTQKGQVGIFS-------FQNNYADSATTFRILAHLDE----------------QRYPLPNG--------AAEKNLPSLFEGFKATVSIIQQRLLLDN-----------------VDGATNSDKEKYVQLPDINTGFVN----------KTYSRIDLTHLLEDVETNVENLSINKTLEMDELTRLDSMINELESRKLKILERVKHIDSKSTNLENDVTLIKDRINFIEEYNLEADREQSLRKQMEE---ERSSEASSFTQNEEAISSLCDVESKDTRLKDFYKMPHEKSHDKNRQIISETYSRNTTAFR-----------MTIPHGEHGNSITALDFDTPWGTLCSSSYQDRIVKVWDLNHGIQVGELPGHLATVNCMQIDKKNYNMLITGSKDATLKLWDLNLSREIYLDHSPLKEKTEEIVTPCIHNFELHKDEITALSFDSEALVSGSRDKKIFHWDLTTGKCIQQLDLIFTPTHSDIKMPARSLNNGACLLGTEAPMIGALQCYNSALATGTKDGIVRLWDLRVGKPVRLLEGHTDGITSLKFDSEKLVTGSMDNSVRIWDLRTSSILDVIAYDLPVSSLD-FDGKLITVGANEGGVNVFNMERDEHWMTPEPPHSLDGDELSRRIAIVKYKDGFLINGHNDGDINVWTL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P47025-1", "uniprot_id": "MDV1_YEAST", "id": "P47025-1", "name": "Mitochondrial division protein 1", "aln": "MSVNDQITHIGKTLSTTASAFLNYQKSNSNTQDVLTNNGPYKNLLSNTVNNASSTSYFYKRTEHGRFVKNASNTFEDIYSKTRRGDVFRNKFTDNKTCFRMLTYISDDLLNEIPTKEGLKSDADGKLLTEGGENENLRKNASKKETSLFQGFKSYLPIAELAIENTERLNYDTNGTSGTVGAKDVMSKTNERDEIHTELPNFQDSFLIPPGVETKKISSSYSPSALKSFSQTLVNSLEFLNIQKNSTLSEIRDIEVEVENLRQKKEKLLGKIANIEQNQLLLEDNLKQIDDRLDFLEEYGLEVIEANSDENAEDDGMSERKALKNDAIRNEGVTTESISSEASNLPPRRRQQLRDDNSLNRLGAFYSKSKKRHRKSFPTFQQLYEPGTKIGSIMSTHDDFLTCLDFDAPFGTLCTAGYLDHTVKIWDLSKQNKIGELAGHLATINCMQIN-RDYGTLVTGGRDAALKLWNLNLAQQLYQETQNLTSPTNHIDSPCVHTFEAHTDEVTALSLDPSFLVSGSQDRTIRQWDLRSGKCLQTIDLSFANVLTTSTNVDLSKSTLLTQR-NERPSIGALQSFDAALATGTKDGVVRLWDLRSGKVIRTLKGHTDAITSLKFDSACLVTGSYDRTVRIWDLRTGLLNKFHAYSAPVLSLDLFQENAAVVVADEPSVQIYDSEKDESWSCVE-----QGNETS--VSTVKYKENYMVEGRENGDVNIWAV", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q1LXQ1-1", "uniprot_id": "Q1LXQ1_DANRE", "id": "Q1LXQ1-1", "name": "", "aln": "-------MGEVRKLQKKLRQIENLEIKISLTPEEKIKVSKKAELRS-------RLAELLLQLSGPQQTQGIVGKEEDKMKR-----------------------------------------------------------QVEEVTEQHVGHRPALKIAREERRENE-----------------ASDGNQTDGRGETNLP--------------------------VSLTEEEQEDAEFRSRKQTWEKAKFR-------------LRALEGHSDIITCAVAVDN-LVISGSRDTTVKVWHVPTATEQR----------NLGGHSGGVTCLCAPPPESCRRLARAFDLADKERFVLSGSTDCCVKIWALSSGQCVKSIY------------------TFNAVTSLCFIPEGEGFIVTGSDAGKLQVWSWSSLENWLSVNAHLDAVTTLQSH---GPLVFSGSAEGSVCVWEVCDEGPEPLRRLHLWGP---EVTGCGGEDGLNGRLVLSPRGDRVFLSCGKASIRILNWRTG----------------VMTRLANHSSTAGVTDCVNQIPGLLIASCFDLANGESTIN----LFSLPQCKYLVSLT-SSDLPRILCFAAWLTASGDHR--------WVTGGRDLIVWEQLPGTFK-KRGDVTVRRDRRLEDCILESDRDSEDDRSED----DADDEDATTQDAPETEEPASSSWLRCVLQ----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . . : : : . . .:. . . :: .. . *.:. : * . : . . .: . .:** : : . * . ::. :: : * .* ::: : .* :: : : . : : . .. .. : :: . * : : : : : .:: : :*.* * . : :. :::*. . : .: .** ::. :* . :.:*. :.:: :*:: * : * : : : * * .*. . * :* * . .: * : ..:: * . .* : *:.* * : * :* * * : .:*. . .. .:. ::. . . . : : ::*. * :.:: . . .: .. :: ", "identical_positions": 39, "similar_positions": 161, "identity": "5.39%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1033", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P25304-1", "uniprot_id": "AGRIN_RAT", "id": "P25304-1", "name": "Agrin", "aln": "------------------------------MPPLPLEHRPRQE--------------------------------------------PGASMLVR-------------------YFMIPCN------------ICLILLATSTLGFAVLLFLSNYK------PGIHFTPAPPTPPDVCRGMLCGFGAVCEPSVEDPGRASCVCKKNACPATVAPVCGSDASTYSNECELQRAQCNQQRRIRLLRQGPCGSRDPCANVTCSFGSTCVPSADGQTASCLCPTTCFGAPDGTVCGSDGVDYPSECQLLSHACASQEHIFKKFNGPCDPCQGSMSDLNHICRVNPRTRHPEMLLRPENCPAQHTPICGDDGVTYENDCVMSRIGATRGLLLQKVRSGQCQTRDQCPETCQFNSVCLSRRGRPHCSCDRVTCDGSYRPVCAQDGHTYNNDCWRQQAECRQQRAIPPKHQGPCDQ-TPSPCHGVQCAFGAVCTVKNGKAECECQRVCSGIYDPVCGSDGVTYGSVCELESMACTLGREIQVARRGPCD--PCGQCRFGSLCEVETGRCVCPSECVESAQPVCGSDGHTYASECELHVHACTHQISLYVASAGHCQTCGEKVCTFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYLSACELREAACQQQVQIEEAHAGPCEPAECGSGGSGSGEDDECEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPRSPVCGSDGVTYGTECDLKKARCESQQELYVAAQGACRGPTLAPLLPVAFPHCAQTPYGCCQDNFTAAQGVGLAGCPSTCHCNPHGSYSGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGHSGCTPCSCDPRGAVRDDCEQMTGLCSCRPGVAGPKCGQCPDGQVLGHLGCEADPMTPVTCVEIHCEFGASCVEKAGFAQCICPTLTCPEANSTKVCGSDGVTYGNECQLKAIACRQRLDISTQSLGPCQESVTPGASPTSAS---MTTPRHILSKTLPFPHNSLPLSPGSTTHDWPTPLPIS-PHTTVSIPRSTAWPVLTVPPTAAASDVTSLATSIFSESGSANGSGDEELSGDEEASGGGSGGLEPPVGSIVVTHGPP--IERASCYNSPLGCCSDGKTPSLDSEGSNCPATKAFQGVLELEGVEGQELFYTPEMADPKSELFGETARSIESTLDDLFRNSDVKKDFWSVRLRELGPGKLVRAIVDVHFDPTTAFQASDVGQALLRQIQVSRPWALAVRRPLQEHVRFLDFDWFPTFFTGAATGTTAAMATARATTVSRLPASSVTPRV-YPSHTSRPVGRTTAPPTTRRPPTTATN-MDRPRTPGHQQPSKSCDSQPCLHGGTCQDQDSGKGFTCSCTAGRGGSVCEKVQPPSMPAFKGHSFLAFPTLRAYHTLRLALEFRALETEGLLLYNGNARGKDFLALALLDGRVQFRFDTGSGPAVLTSLVPVEPGRWHRLELSRHWRQGTLSVDGETPVVGESPSGTDGLNLDTNLYVGGIPEEQVAMVLDRTSVGVGLKGCIRMLDINNQQLELSDWQRAAVQSSGVGECGDHPCLPNPCHGGALCQALEAGMFLCQCPPGRFGPTCADEKSPCQPNPCHGAAPCRVLSSGGAKCECPLGRSGTFCQTVLETAGSRPFLADFNGFSYLELKGLHTFERDLGEKMALEMVFLARGPSGLLLYNGQKTDGKGDFVSLALHNRHLEFCYDLGKGAAVIRSKEPIALGTWVRVFLERNGRKGALQVGDGPRVLGESPKSRKVPHTMLNLKEPLYIGGAPDFSKLARGAAVSSGFSGVIQLVSLRGHQLLTQEHVLRAVDVSPFADHPCTQALGNPCLNGGSCVPREATYECLCPGGFSGLHCEKGLVEKSVGDLETLAFDGRTYIEYLNAVIESELTNEIPAPETLDSRALFSEKALQSNHFELSLRTEATQGLVLWIGKAAERADYMALAIVDGHLQLSYDLGSQPVVLRSTVKVNTNRWLRIRAHREHREGSLQVGNEAPVTGSSPLGATQLDTDGALWLGGLQKLPVGQALPKAYGTGFVGCLRDVVVGHRQLHLLEDAVTKPELRPCPTP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2ASQ1-1", "uniprot_id": "AGRIN_MOUSE", "id": "A2ASQ1-1", "name": "Agrin", "aln": "------------------------------MPPLPLEHRPRQQ--------------------------------------------PGASVLVR-------------------YFMIPCN------------ICLILLATSTLGFAVLLFLSNYK------PGIHFTAAPSMPPDVCRGMLCGFGAVCEPSVEDPGRASCVCKKNVCPAMVAPVCGSDASTYSNECELQRAQCNQQRRIRLLRQGPCGSRDPCANVTCSFGSTCVPSADGQTASCLCPTTCFGAPDGTVCGSDGVDYPSECQLLRHACANQEHIFKKFDGPCDPCQGSMSDLNHICRVNPRTRHPEMLLRPENCPAQHTPICGDDGVTYENDCVMSRIGAARGLLLQKVRSGQCQTRDQCPETCQFNSVCLSRRGRPHCSCDRVTCDGAYRPVCAQDGHTYDNDCWRQQAECRQQQTIPPKHQGPCDQ-TPSPCRGAQCAFGATCTVKNGKAVCECQRVCSGGYDPVCGSDGVTYGSVCELESMACTLGREIRVARRGPCD--RCGQCRFGSLCEVETGRCVCPSECVESAQPVCGSDGHTYASECELHVHACTHQISLYVASAGHCQTCGETVCTFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYLSACELREAACQQQVQIEEARAGPCEPAECGSGGSGSGEDNACEQELCRQHGGVWDEDSEDGPCVCDFSCQSVLKSPVCGSDGVTYSTECHLKKARCEARQELYVAAQGACRGPTLAPLLPMASPHCAQTPYGCCQDNVTAAQGVGLAGCPSTCHCNPHGSYSGTCDPVTGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGHSGCTPCSCDPRGAVRDDCEQMTGLCSCRPGVAGPKCGQCPDGQALGHLGCEADPTTPVTCVEMHCEFGASCVEEAGFAQCVCPTLTCPEANSTKVCGSDGVTYGNECQLKTIACRQRLDISIQSLGPCRESVAPGVSPTSAS---MTTPRHILSRTLASPHSSLPLSPSTTAHDWPTPLPTS-PQTVVGTPRSTA---------ATPSDVASLATAIFRESGSTNGSGDEELSGDEEASGGGSGGLEPPVGSVVVTHGPP--IERASCYNSPLGCCSDGKTPSLDSEGSNCPATKAFQGVLELEGVEGQELFYTPEMADPKSELFGETARSIESTLDDLFRNSDVKKDFWSIRLRELGPGKLVRAIVDVHFDPTTAFQAPDVGQALLQQIQVSRPWALAVRRPLREHVRFLDFDWFPTFFTGAATGTTAAVATARATTVSRLSASSVTPRV-YPSYTSRPVGRTTAPLTTRRPPTTTAS-IDRPRTPGPQRPPKSCDSQPCLHGGTCQDLDSGKGFSCSCTAGRAGTVCEKVQLPSVPAFKGHSFLAFPTLRAYHTLRLALEFRALETEGLLLYNGNARGKDFLALALLDGHVQFRFDTGSGPAVLTSLVPVEPGRWHRLELSRHWRQGTLSVDGEAPVVGESPSGTDGLNLDTKLYVGGLPEEQVATVLDRTSVGIGLKGCIRMLDINNQQLELSDWQRAVVQSSGVGECGDHPCSPNPCHGGALCQALEAGVFLCQCPPGRFGPTCADEKNPCQPNPCHGSAPCHVLSRGGAKCACPLGRSGSFCETVLENAGSRPFLADFNGFSYLELKGLHTFERDLGEKMALEMVFLARGPSGLLLYNGQKTDGKGDFVSLALHNRHLEFRYDLGKGAAIIRSKEPIALGTWVRVFLERNGRKGALQVGDGPRVLGESPKSRKVPHTMLNLKEPLYVGGAPDFSKLARGAAVASGFDGAIQLVSLRGHQLLTQEHVLRAVDVAPFAGHPCTQAVDNPCLNGGSCIPREATYECLCPGGFSGLHCEKGIVEKSVGDLETLAFDGRTYIEYLNAVTESELTNEIPAPETLDSRALFSEKALQSNHFELSLRTEATQGLVLWIGKVGERADYMALAIVDGHLQLSYDLGSQPVVLRSTVKVNTNRWLRVRAHREHREGSLQVGNEAPVTGSSPLGATQLDTDGALWLGGLQKLPVGQALPKAYGTGFVGCLRDVVVGHRQLHLLEDAVTKPELRPCPTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00468-1", "uniprot_id": "AGRIN_HUMAN", "id": "O00468-1", "name": "Agrin", "aln": "MAGRSHPGPLRPLLPLLVVAACVLPGAGGTCPERALERREEEANVVLTGTVEEILNVDPVQHTYSCKVRVWRYLKGKDLVARESLLDGGNKVVISGFGDPLICDNQVSTGDTRIFFVNPAPPYLWPAHKNELMLNSSLMRITLRNLEEVEFCVEDK------PGTHFTPVPPTPPDACRGMLCGFGAVCEPNAEGPGRASCVCKKSPCPSVVAPVCGSDASTYSNECELQRAQCSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRGAPEGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPCDPCQGALPDPSRSCRVNPRTRRPEMLLRPESCPARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQCPEPCRFNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGPCDQ-APSPCLGVQCAFGATCAVKNGQAACECLQACSSLYDPVCGSDGVTYGSACELEATACTLGREIQVARKGPCD--RCGQCRFGALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCETCGDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEEARAGPCEQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITAARGVGLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQGLQISIQSLGPCQEAVAPSTHPTSASV-TVTTPGLLLSQALPAPPGALPLAPSSTAHSQTTPPPSSRPRTTASVPRTTVWPVLTVPP-TAPSPAPSLVASAFGESGSTDGSSDEELSGDQEASGGGSGGLEPLEGSSVATPGPP--VERASCYNSALGCCSDGKTPSLDAEGSNCPATKVFQGVLELEGVEGQELFYTPEMADPKSELFGETARSIESTLDDLFRNSDVKKDFRSVRLRDLGPGKSVRAIVDVHFDPTTAFRAPDVARALLRQIQVSRRRSLGVRRPLQEHVRFMDFDWFPAFITGATSGAIAAGATARATTASRLPSSAVTPRAPHPSHTSQPVAKTTAAPTTRRPPTTAPSRVPGRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGAPVPAFEGRSFLAFPTLRAYHTLRLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSGPAVLTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSGVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPLGREGTFCQTASGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKMALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIRSREPVTLGAWTRVSLERNGRKGALRVGDGPRVLGESPKSRKVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQVDVTSFAGHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVDTLAFDGRTFVEYLNAVTESELANEIPVPETLDSGALHSEKALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGHLQLSYNLGSQPVVLRSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPLGATQLDTDGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPLHLLEDAVTKPELRPCPTP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PKT2-1", "uniprot_id": "A0A8M9PKT2_DANRE", "id": "A0A8M9PKT2-1", "name": "Agrin", "aln": "MGSADRKAVYWPVWSFALVFVLLIQRCHGGCSEKELEKREEEANVVLTGTVEEILNMDPVHNTYSCKVRVWRYLKGKTMVNGEVLLDGGNKVMIGGFGDPHICDNQVATGDTRIFFVNLAPEYMWPNHKNELMLNSSLMRITLRNLEEVEHCVEDHKMIIADKPVHFTPAP--PPDGCRGKLCGFGAVCERDQADPSKGECVCKKIVCTSVVAPVCGSDSSTYSNECELEKAQCNTQRRIKVMRKGPCALKDPCSEVTCSFGSTCIQSSDGLSAKCMCPLSCENVPKHVVCGSDGLDYQSECELNMKACATQKNIRVHHQGRCDPCSDTLNSLSTACRVNPKTYQQITFAPAESCPPDEMPICASDGHTYESMCQMERTALKNNLELKKVSLGSCKEKGGCPNGCKFNAICLLDNGEFRCSCDPIQCDGTYKPLCGKDGKTYPNDCERKLQECRTQKDIPVKQQGPCDLNLESPCLKKTCEFGAVCVVKNSEAVCECSDACPQDQDPVCGSDGHTYSSSCQMKAMGCALQKQIQMQHKGPCADESCTNCSFGAICDAQTGRCVCPKGCLETRQPVCGSDGTTYDNECKLNVQACTKQLDLKVVAHGECKTCGSTVCSWGSQCVNNKCECQQCTGQPVKPVCGSDGNTYNNDCELRLASCQKQRKIEVAKPGVCD-EDCGSGGSGSGSE-TCEQDRCRRYGGTWDDDMEDERCVCELNCQIVLHSPVCGSDGNTYSSDCELKKTRCEKQIDLSVQSQGPCPTIVSPPPELVASQHCSQTVYGCCEDNKTAALGVGLAGCPSMCQCNHYGSYGGTCDPSTGQCSCKPGVGGLKCDRCEPGFWNFRGIVTENMSGCTPCNCDGVGSVRDDCEQMSGLCSCKPGVKGMKCNVCPDGSKMGVNGCDKGPKAPKSCAELVCHFGSSCVEVNGQAHCECPSPDCDEKNKTKVCGSDGVTYADRCQLKTIACRQDKEIKVEHLGQCKESIELTAKPTPFPTTHRTTPPTAHVKVTKQRHGHRTTTPDSYVVEAMPPPRLDGARKFSSPFTTHR------PTTPYKPLRTSSPPLDFDESGSGEPSGDDEMVSGMEESG------EEPLGTTVATTTLPTAEERSSCDNTAFGCCPDGKTAAVNSEGTNCPSTMRFSGFLHLDKVEGQEVFYTPEMEDPKSELFGETARSIESAMNELFRKSDVQKDFQSVRVRNLSPSNSIIAHFEAHFDPDTRFNVGDIEGALLKQLKASKDTGIVVKKPEEENIRINNYGLSTVPFFTTTTTTVASVTTPTTTTTTMSPSSAYTTLR--PITTRRPFTRTTTPAPATTTAPHVPKTTVSLMNRLGPHAHSPCDSQPCRHGGTCEEDD--NDFTCICPAGRGGAVCEKVIKYFIPSFGGKSYMAFQTMKAYHTVRIAMEFRASEMTGILLYNGQKSKKDFLSLTLVEGYVELRFNTGSGTASVISKVLVKPGRWHQLVVVRNRRNAMLSVDNEPSVEGQSPPGTDGLNLDTDLFIGGVLDDMSADVKERTSVSAGLVGCIRMLDVNNLVYNLQENGGSVLYGSAIGECGNNPCLPNPCKNGASCQVKEAEIFHCKCVNGFSGPTCADAHNPCDPNKCHPPSRCQVLPEGGYKCECPMGREGRHCEKVSDKGG--AFIPYFTGDSFLELKGLHTYNQDLRQKFSMTIVLLANDSKGMIFYNGQKTDGKGDFISLSLNDGILEFRYDLGKGPAVIRSKEKIKLNEWNTVNLERASRKGEISINGKDPVRGEAPKSRKNQHTDLNLKESLFVGGAPDFRKVARAAAIKDGFKGAIQKITLMGIPILKADNALSSTDVSMYPNHPCSKDV---CENGGRCNPQLNSYECACRHGFSGHHCQDTIFEKSAGDTEAIAFDGHTFIEYHNGVTKSQLTNEIPDPESLENPSDQSEKALLVNKFELSIRTEATHGLILWSGKGVERSDYIALAIVDGRVQMTYDLGSKPVVLRSTVRVNTNHWIRIKASRALRDGSLQVGNEAAVTGSSPLAATQLDTDGALWLGGLEELSVARRLPKAYSTGFIGCVKDVIVDGVELHLVEDALNTPKISHCSAK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **:* .: * .::: :*: . : *: : .: : . : : ***..* *** *** ********* . .*.:..***** *.: ********:*********::***. ****::: :***. :***::********* *:** :*.*:** :* ..*. .****** ** .**:* :*** *::: :.:* ****..:: . . *****:* : : .*.**. . *:*..** ***. * * * . ..* *:** *.*: :. **: *:**::** .*. :**** : ***:*:*:*.:**:** .** *: *** *: ** *:***** *** * ***.*.***.:* *** .*. ******** **.* *:::: .*:* ::*:: ::*** * :* **::*:.:*******. *: ******** ** .** *:*:***:*:.* *.: * *:***. **::*: * .:* * :* * ******* ** . **** *:* :* :** *:.* *: :*********.: ***: **: ** **:* ** ***::.** * ******** **.::*.***:*** : * * :**.* . .* :* **:** ****:** *** ********* *:** :***.***** ******:******:****************:. ******.** *:********:*****:*** * **. **** :* **: .. :* :*.*: *.**: *** * *:* ** * * * ***********.:.****:***** :*. : ** *:*:: . **. . *** :. . . :*.: . . .* . .:. . : . . .* . * **** : *.*:*: .. * ** * *: *.* * **:** *:.:***.****.::::**:***:* *.*.*.*: *****:****** ****************::::***:***:*** *:*:*:*.*.: : * .:.**** * *.. *: ***:*::.*: .: *::* .*::*: ::. .. : ::: : *: :*. :**.: .:*: *. * * :*. :**:. .: ... ... :. ..****** *****:: .*:* *.***.*:***** :*:* *:*::** *::****:*:*:**** * *:*****: ****:*:*::* *::**:****.* : * * *:**:**:* : *: *.. ****.*..* *:**.*********.*::**: :: * . :** *. ** ****:**:** :* :. .*.:****::** ****:.** ** ** * *:* * ****** :.**:** ** .: *:**. ** :* **:**.* .*:.. * .*:. *.* *.***:****: :** :*::: :*:**....*:::************:**:*.: *** ******.*:***:* : *. * * *** .*** : :.. * **:***** ** *****.*::****** *:**.**: .**.*.** ::* * :*. ::.* .**: :..***:: * **. * *: :* * * **** **:. :.***.** :::****:*::** *.* :*:*:**** **:*:. : ***** *:****:*****:**:** ** **:**:*******::*::*:***:******** ****:*:*: * * *:*********.*******.*************** :*.*. *****.***:**::**:*. ***:***:..*:: *.: ", "identical_positions": 963, "similar_positions": 517, "identity": "46.28%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-105", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A5Q2-1", "uniprot_id": "D4A5Q2_RAT", "id": "D4A5Q2-1", "name": "Structural maintenance of chromosomes protein", "aln": "MYVKSIILEGFKSYAQRTEVNGFDPLFNAITGLNGSGKSNILDSICFLLGISNLSQVRASNLQDLVYKNGQAGITKASVSITFDNSDKKQSPLGFEAHDEITVTRQVVIGGRNKYLINGVNANNTRVQDLFCSVGLNVNNPHFLIMQGRITKVLNMKPPEILSMIEEAAGTRMYEYKKIAAQKTIEKKEAKLKEIKTILEEEITPTIQKLKEERSSYLEYQKVMREIEHLSRLYIAYQFLLAEDTKERSAGELKEMQDKILKLQEVLSENEKKIKALNCEIEELEKRKDKETG--GILRSLEDAFAEAQRVNTKSQSAFDLKKKNLASEETKRKELEKNMAEDSKALAAKEKEVKKLTDGLHGLQEASNKDAEALAAAQQHFNAVSAGLSSNEDGAEATLAGQMMACKNDISKAQTGAKQAQMKLKHAQQELKNKQAEVRKMDSGYKKDQEAFEAVKKVKEKLETEMKKLNYEDNKEERLLEKHRQVSRDISNLKGTYEALLAKFPNLRFAYKDPEKNWNRNCVKGLVASLINVKD--NSTATALELVAGERLYNVVVDTEVTGKKLLEKGELKRRYTIIPLNKISARCIAPETLRVAQNLVGPNNVHVALSLVDYKPELQKAMEFVFGTTFVCNNMDNAKKVAFDKRIMTRTVTLGGDVFDPHGTLSGGARSQAASILTKFQELKDVQAELRTKEKELQALEEELAGLKNVAEKYRQLKQQWEMKTEEGDLLQTKLQQSSYHKQQEELDALKKTIEESEETLKNTKEIQKKAEEKYEALENKMKNAEAEREKELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKREHASNEQQLDAVNEAIKAYEGQIEIMAAEVAKNKESVNKAQNELMKQKEIISAQDNIIKDKCAEVAKHNLQNNDSQLKIKELDHSISKHKREADDAAAKVSKMLNDYDWINAEKHLFGQPNSAYDFKTNNPKEAGQRLQKLQEVKEKLGRNVNMRAMNVLTEAEERYNDLMKKKRIVENDKSKILATIEDLDQKKNQALNIAWQKVNKDFGSIFSTLLPGANAMLAPPEGQTVLDGLEFKVALGNTWKENLTELSGGQRSLVALSLILSMLLFKPAPIYILDEVDAALDLSHTQNIGQMLRTHFTHSQFIVVSLKEGMFNNANVLFKTKFVDGVSTVARFTQSQNGR-IPKEAKAKGKGPS-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CG48-1", "uniprot_id": "SMC2_MOUSE", "id": "Q8CG48-1", "name": "Structural maintenance of chromosomes protein 2", "aln": "MYVKSIILEGFKSYAQRTEVNGFDPLFNAITGLNGSGKSNILDSICFLLGISNLSQVRASNLQDLVYKNGQAGITKASVSITFDNSDKKQSPLGFEAHDEITVTRQVVIGGRNKYLINGVNANNTRVQDLFCSVGLNVNNPHFLIMQGRITKVLNMKPPEILSMIEEAAGTRMYEYKKIAAQKTIEKKEAKLKEIKTILEEEITPTIQKLKEERSSYLEYQKVMREIEHLSRLYIAYQFLRAEDTKERSAGELKEMQDKIVNLQEVLSENEKKIKALNCEIEELERRKDKETG--GKLKSLEDACAEAQRVNTKSQSAFDLKKKNLASEETKRKELQNSMAEDSKALAAKEKEVKKITDGLHGLQEASNKDAEALAAAQQHFNAVSAGLSSNEDGAEATLAGQMIACKNDISKAQTEAKQAQMKLKHAQQELKSKQAEVKKMDSGYKKDQDAFEAVKKAKEKLETEMKKLNYEENKEEKLLEKHRQLSRDINNLKGKHEALLAKFPNLQFAYKDPEKNWNRNSVKGLVASLINVKD--NSTATALEVVAGERLYNVVVDTEVTAKKLLEKGELKRRYTIIPLNKISARCIAPETLRVAQNLVGPDNVHVALSLVDYKPELQKGMEFVFGTTFVCNNMDNAKKVAFDKRIMTRTVTLGGDVFDPHGTLSGGARSQAASILTKFQEVKDVQDELRTKENELRALEEELAGLKNVAEKYRQLKQQWEMKTEEGDLLQTKLQQSSYHKQQEELDALKKTIEESEETLKSTKEIQKKAEEKYEALENKMKNAEAEREKELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKREHASNEQQLDAVNEAIKAYEGQIEKMAAEVAKNKESVNKAQDELMKQKQIITAQDNIIKDKCAEVAKHNLQNNESQLKIKELDHSISKHKREADDAAAKVSKMLSDYDWINAEKHLFGQPNSAYDFKTNNPKEAGQRLQKLQEVKEKLGRNVNLRAMNVLTEAEERYNDLMKKKRIVENDKSKILATIEDLDQKKNQALNIAWQKVNKDFGSIFSTLLPGANAMLAPPEGQTVLDGLEFKVALGNTWKENLTELSGGQRSLVALSLILSMLLFKPAPIYILDEVDAALDLSHTQNIGQMLRTHFTHSQFIVVSLKEGMFNNANVLFKTKFVDGVSTVARFTQSQAGK-IPKEAKSRGKEPN-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95347-1", "uniprot_id": "SMC2_HUMAN", "id": "O95347-1", "name": "Structural maintenance of chromosomes protein 2", "aln": "MHIKSIILEGFKSYAQRTEVNGFDPLFNAITGLNGSGKSNILDSICFLLGISNLSQVRASNLQDLVYKNGQAGITKASVSITFDNSDKKQSPLGFEVHDEITVTRQVVIGGRNKYLINGVNANNTRVQDLFCSVGLNVNNPHFLIMQGRITKVLNMKPPEILSMIEEAAGTRMYEYKKIAAQKTIEKKEAKLKEIKTILEEEITPTIQKLKEERSSYLEYQKVMREIEHLSRLYIAYQFLLAEDTKVRSAEELKEMQDKVIKLQEELSENDKKIKALNHEIEELEKRKDKETG--GILRSLEDALAEAQRVNTKSQSAFDLKKKNLACEESKRKELEKNMVEDSKTLAAKEKEVKKITDGLHALQEASNKDAEALAAAQQHFNAVSAGLSSNEDGAEATLAGQMMACKNDISKAQTEAKQAQMKLKHAQQELKNKQAEVKKMDSGYRKDQEALEAVKRLKEKLEAEMKKLNYEENKEESLLEKRRQLSRDIGRLKETYEALLARFPNLRFAYKDPEKNWNRNCVKGLVASLISVKD--TSATTALELVAGERLYNVVVDTEVTGKKLLERGELKRRYTIIPLNKISARCIAPETLRVAQNLVGPDNVHVALSLVEYKPELQKAMEFVFGTTFVCDNMDNAKKVAFDKRIMTRTVTLGGDVFDPHGTLSGGARSQAASILTKFQELKDVQDELRIKENELRALEEELAGLKNTAEKYRQLKQQWEMKTEEADLLQTKLQQSSYHKQQEELDALKKTIEESEETLKNTKEIQRKAEEKYEVLENKMKNAEAERERELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKREHTSYKQQLEAVNEAIKSYESQIEVMAAEVAKNKESVNKAQEEVTKQKEVITAQDTVIKAKYAEVAKHKEQNNDSQLKIKELDHNISKHKREAEDGAAKVSKMLKDYDWINAERHLFGQPNSAYDFKTNNPKEAGQRLQKLQEMKEKLGRNVNMRAMNVLTEAEERYNDLMKKKRIVENDKSKILTTIEDLDQKKNQALNIAWQKVNKDFGSIFSTLLPGANAMLAPPEGQTVLDGLEFKVALGNTWKENLTELSGGQRSLVALSLILSMLLFKPAPIYILDEVDAALDLSHTQNIGQMLRTHFTHSQFIVVSLKEGMFNNANVLFKTKFVDGVSTVARFTQCQNGK-ISKEAKSKAKPPKGAHVEV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A5K9-1", "uniprot_id": "B8A5K9_DANRE", "id": "B8A5K9-1", "name": "Structural maintenance of chromosomes protein", "aln": "MYIKSIVLEGFKSYAERTEINGFDPFFNAITGLNGSGKSNILDSICFLLGISNLSQVRATNLQDLVYKNGLAGITKATVSITFDNSNKKQSPLGFETHDEITITRQVVIGGRNKYLINGVNANNLRVQDLFCSVGLNVNNPHFLIMQGRITKVLNMKPPEILAMIEEAAGTRMYECKKISAQKTIEKKDAKLKEIQTILDEEITPAMEKLKEERASYLEYQKLMREIEHLSRLYVAYLFVCAEETKLKSNEELQEMQSSIAKLQENMKQNEAKVKELSAEIQELERRRDKEVG--GVLRTLEETLSEAQRVDTKAQSALDLKKQNLKDETKKRKELVKNMEEDKKVMSAKEAEVAKAVERLKAVKEEGQKDAEALEAAQQHFKAVSAGLSANEDGAEATLSGQMMTCKNDISKAETEAKQAQMKLKHAQQELKTKQAQVKKMDSGYKKDQDTFEAVNKCIEKLQAEMKKLNYEDGREECLLEQKRQFSREVIQLREAYESLMGQFPNLRFEYTDPERNWERSKVKGLVANLFTVTD--VSNATALEVVAGGRLYNVVVDNEVTGKKLLEKGELRRRYTIIPLNKISARTLNDNVVRTAKKLVGPDNVHTALSLVGYESELRKAMEYVFGTTLVCDSLDNAKKVAFDKGVSTKTVTLGGDVFDPQGTLTGGARAQTASVLSKLAEVKDIQDSLRNKEAELSAVESELSGLKGTAEKYRQLKQQLDLKTEEARILETKLQQSSFHKQQEELENLRKTIEECEDTLQKTKEVQKKAEEKYNVLENKMKNAAAEREKELKAAQQKLNQAKSKADAFSKRLKEKQQEADAVALELEELKREQAGYEQQIQAVDEALKAVQEQIDNMTTEVSANKEAVRVAQEKLSQQKEVIMGQEREIKGKSGEANRLREQNNDAQLKIKELEHNISKHKKDSADATAKVARMLAENDWISSEKHLFGQPNTAYDFKTNNPKEAGQRLKRLEETKDKLERNVNRRAMNMLSEAEERYNDLKKKKRIVENDKAKILETIEELDQKKNEALNVAWQKVNKDFGSIFSTLLPGANARLAPPEGCGVLDGLEFKVALGNTWKENLTELSGGQRSLVALSLILAMLLFKPAPIYILDEVDAALDLSHTQNIGQMLRTHFTHSQFVVVSLKDGMFTNANVLFKTKFVDGISTVTRTAQTHEGKVLAQRTQEKAKDKRQRQILAS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38989-1", "uniprot_id": "SMC2_YEAST", "id": "P38989-1", "name": "Structural maintenance of chromosomes protein 2", "aln": "MKVEELIIDGFKSYATRTVITDWDPQFNAITGLNGSGKSNILDAICFVLGIASMSTVRASSLQDLIYKRGQAGVTKASVTIVFDNTDKSNSPIGFTNSPQISVTRQVVLGGTSKYLINGHRAPQQSVLQLFQSVQLNINNPNFLIMQGKITKVLNMKPSEILSLIEEAAGTKMFEDRREKAERTMSKKETKLQENRTLLTEEIEPKLEKLRNEKRMFLEFQSTQTDLEKTERIVVSYEYYNIKHKHTSIRETLENGETRMKMLNEFVKKTSEEIDSLNEDVEEIKLQKEKELHKEGTISKLENKENGLLNEISRLKTSLSIKVENLNDTTEKSKALESEIASSSAKLIEKKSAYANTEKDYKMVQEQLSKQRDLYKRKEELVSTLTTGISSTG-AADGGYNAQLAKAKTELNEVSLAIKKSSMKMELLKKELLTIEPKLKEATKDNELNVKHVKQCQETCDKLRARLVEYGFDPSRIKDLKQREDKLKSHYYQTCKNSEYLKRRVTNLEFNYTKPYPNFEASFVHGVVGQLFQIDNDNIRYATALQTCAGGRLFNVVVQDSQTATQLLERGRLRKRVTIIPLDKIYTRPISSQVLDLAKKIA-PGKVELAINLIRFDESITKAMEFIFGNSLICEDPETAKKITFHPKIRARSITLQGDVYDPEGTLSGGSRNTSESLLVDIQKYNQIQKQIETIQADLNHVTEELQTQYATSQKTKTIQSDLNLSLHKLDLAKRNLDANPSSQIIARNEEILRDIGECENEIKTKQMSLKKCQEEVSTIEKDMKEYDSDKGSKLNELKKELKLLAKELEEQESESERKYDLFQNLELETEQLSSELDSNKTLLHNHLKSIESLKLENSDLEGKIRGVEDDLVTVQTELNEEKKRLMDIDDELNELETLIKKKQDEKKSSELELQKLVHDLNKYKSNTNNMEKIIEDLRQKHEFLEDFDLVRNIVKQNEGIDLDTYR---ERSKQLNEKFQELRKKVNPNIMNMIENVEKKEAALKTMIKTIEKDKMKIQETISKLNEYKRETLVKTWEKVTLDFGNIFADLLPNSFAKLVPCEGKDVTQGLEVKVKLGNIWKESLIELSGGQRSLIALSLIMALLQFRPAPMYILDEVDAALDLSHTQNIGHLIKTRFKGSQFIVVSLKEGMFANANRVFRTRFQDGTSVVSIM----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::.::::****** ** :..:** *****************:***:***:.:* ***:.****:**.* **:***:*:*.***::*.:**:** :*::*****:** .****** .* : * :** ** **:***:******:*********.***::*******:*:* :: *::*:.**::**:* :*:* *** * ::**::*: :**:*. ::*: .*: ::* : :..: *:: : : *:* :.:.. ::. *. :::*:: :::** * : .**: . :: ::::.:* :** * * * ..: ... : *: : . : ::* .*: : :: ..::::*:*:. .*:. .*: .*.::.:.. *::.**:: ::** . :.:::: .. . : . .: :. :**.:.: : .:: .: : * ::. :.. . . * * :..**.* *..* *:: . *:*:*..*: : : :***: ** **:****: . *..:***:*.*::* *****:** :* : :.: *:::. *.:*. *:.*: :. .: *.**::**.:::*:. :.***::*. : ::::** ***:**.***:**:* : *:* .: : :::* .:. : :* : .** .::* : ::.: ::. .: : : :*: .. : . : : : * *.*: ::..: :*.:*: ..:*:.**: ::: :*: :::*. .: : ... :.* : : : ** *:*. * . : :. ::::: : : . : :: :: : .* :: ::*: : : :: : . :::.::*::::* *.:.*:* :: : : : . :::. : . : .:. :. : :* ::*:* ::* ::** . **:: :.*:: * . : :*:** ** **..*:: *.::* :*:**. ***.**: ***.: * *.* ** * :***.** *** ***.* *********:*****:::* *:***:*******************::::*:*. ***:*****:*** *** :*:*:* ** *.*: ", "identical_positions": 373, "similar_positions": 462, "identity": "31.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1050", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07687-1", "uniprot_id": "HYEP_RAT", "id": "P07687-1", "name": "Epoxide hydrolase 1", "aln": "-------------------------MWLELVLASLLGFVIYWFVSRDKEETLPLGDGWWGPGSKPSAKEDESIRPFKVETSDEEIKDLHQRIDRFRASPPLEGSRFHYGFNSNYMKKVVSYWRNEFDWRKQVEILNQYPHFKTKIEGLDIHFIHVKPPQLPSGRTPKPLLMVHGWPGSFYEFYKIIPLLTDPKSHGLSDEHVFEVICPSIPGYGYSEASSKKGLNSVATARIFYKLMTRLGFQKFYIQGGDWGSLICTNMAQMVPNHVKGLHLNMAFISRS--FYTMTPLLGQRFGRFLGYTEKDIELLYPYKEKVFYSIMRESGYLHIQATKPDTVGCALNDSPVGLAAYILEKFSTWTKSEYRELEDGGLERKFSLDDLLVNIMIYWTTGTIVSSQRYYKENLGQGIMVHKHEGMKVFVPTGFSAFPSELLHAPEKWVKVKYPKLISYSYMERGGHFAAFEEPKLLAQDIRKFVSLAELQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D379-1", "uniprot_id": "HYEP_MOUSE", "id": "Q9D379-1", "name": "Epoxide hydrolase 1", "aln": "-------------------------MWLELILASVLGFVIYWFVSRDKEETLPLEDGWWGPGSKPSAKEDESIRPFKVETSDEEIKDLHQRIDRFRASPPLEGSRFHYGFNSSYLKKVVSFWRNEFDWRKQVEILNQYPHFKTKIEGLDIHFIHVKPPQLPSGRTPKPLLMVHGWPGSFYEFYKIIPLLTDPKTHGLSDEHVFEVICPSIPGYGFSEASSKKGLNSVATARIFYKLMSRLGFQKFYIQGGDWGSLICTNIAQMVPNHVKGLHLNMSFISRN--IYSLTPLLGQRFGRFLGYTEKDLELLYPFKEKVFYNIMRESGYLHIQATKPDTVGCALNDSPVGLAAYILEKFSTWTKSEYRELEDGGLERKFSLEDLLTNIMIYWTTGTIVSSQRFYKENLGQGVMVHRHEGMKVFVPTGYSAFPSEILHAPEKWVKVKYPKLISYSYMERGGHFAAFEEPKLLAQDIRKFVSLAELQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07099-1", "uniprot_id": "HYEP_HUMAN", "id": "P07099-1", "name": "Epoxide hydrolase 1", "aln": "-------------------------MWLEILLTSVLGFAIYWFISRDKEETLPLEDGWWGPGTRSAAREDDSIRPFKVETSDEEIHDLHQRIDKFRFTPPLEDSCFHYGFNSNYLKKVISYWRNEFDWKKQVEILNRYPHFKTKIEGLDIHFIHVKPPQLPAGHTPKPLLMVHGWPGSFYEFYKIIPLLTDPKNHGLSDEHVFEVICPSIPGYGFSEASSKKGFNSVATARIFYKLMLRLGFQEFYIQGGDWGSLICTNMAQLVPSHVKGLHLNMALVLSN--FSTLTLLLGQRFGRFLGLTERDVELLYPVKEKVFYSLMRESGYMHIQCTKPDTVGSALNDSPVGLAAYILEKFSTWTNTEFRYLEDGGLERKFSLDDLLTNVMLYWTTGTIISSQRFYKENLGQGWMTQKHERMKVYVPTGFSAFPFELLHTPEKWVRFKYPKLISYSYMVRGGHFAAFEEPELLAQDIRKFLSVLERQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QAE5-1", "uniprot_id": "A0A8M9QAE5_DANRE", "id": "A0A8M9QAE5-1", "name": "Epoxide hydrolase", "aln": "MGFQDTVLQTIDSVKGTLDNLDRSKLQLLALSSAGVGALLCYLSWRKGPKTIPIGDGWWGAGQK-SLTEDKTIQRFVVKTSVEEIEDLHKRIDLTRFTDPLEDSKFNYGFNSTYLRRVVSYWRHQFNWEKQVKVINQYPHFKTKIEGIDVHFVHVRPLQK-SGQTVVPLMMVHGWPGSFYEFYGIIPLLTKTDSN-----VVFEVICPSIPGYGYSEAPHKKGFNTMEAARIFLKLMERLGFSEFYVQGGDWGAFITSNMAQMKPDCVRGLHLNMVIARTDSTAQLLSLVIGRYLPFLVGFTKEDVRRLYPYMEKNIYDILRETGYLHIQATKPDTAGCGLNDSPVGLAAYILEKFSTWTNLENRDLEDGGLERKFNLDDLLTNVMIYWTTCSIIPSMRFYKENLKKDFKTRVDRVTSIHVPTGLAAFPDELLHCPRAWASSRFSDVRSFTYMPRGGHFAAFEEPQLLAQDIIQFAEKVEGKSHKSL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : :: :* : :: *. :*:*: *****.* : : **.:*: * *:** ***.***:*** * : ***.* *:*****.*:::*:*:**::*:*.***:::*:**********:*:**:**:* * :*:* **:************* ******....: *************:***. ***:*:: :**** *** ****.:**:******::* :*:**: *. *:****** : . :: ::*: : ::* *:.*:. *** ** :*.::**:**:***.*****.*..********************: * * **********.*:***.*:*:**** :*:.* *:***** :. .: .. .:.**** :*** *:** *. *. ::..: *::** ***********:****** :* . * : ", "identical_positions": 247, "similar_positions": 124, "identity": "50.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1055", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09913-1", "uniprot_id": "IFIT2_HUMAN", "id": "P09913-1", "name": "Interferon-induced protein with tetratricopeptide repeats 2", "aln": "MSEN-NKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAYLKHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKVKHVCEKFSSP--YRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGLAIASYRLDNWPPSQN-----AIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMNLRENGMYG--KRKLLELIGHAVAHLKKADEANDNLFRVCSILASLHALADQYEDAEYYFQKEFS-KELTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKMKDKLQKIAKMRLSKNGADSEALHVLAFLQELNEKMQQADEDSERGLESGSLIPSASSWNGE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09914-1", "uniprot_id": "IFIT1_HUMAN", "id": "P09914-1", "name": "Antiviral innate immune response effector IFIT1", "aln": "MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQ---DEGQE-AEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFEN-SVRQGP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P5X8-1", "uniprot_id": "A0A8M1P5X8_DANRE", "id": "A0A8M1P5X8-1", "name": "", "aln": "-----MNSLLKRGLEKLECHFTWDLGQYQNELQGMK-REMDLDVPQKISSPVHYYNLLGFIQKSLGSDREALESLQKAESVIQEQGTEETAVRLLVNKANMAWVHFHLGELEKSRGYLEELEELQRIHPAPPGCPLH-PEVSGEKGWTLVKFNKSKKRLAIDYFKMALEAEPERKEWHKGLAISMSKACLWYKCTPEQKAEILEKVKTAAEINPNDLLLQALYLVKLS-YVTKVNVEREMRDLLERCLEIVN--VPGLNIILKYLG-DISFDESIREGERFQERYPESIKVLKCLADTYKWKVYKMNEDT---------EERVILARKTIELLEKVCGYNPDSHRAKVALAAMHYYAHNTERADEIYQQLLLEEELSPDKWQYIYYCYASYLN-QCKRFSESVQFHIKGVKTPGDSVDKEKSLNILKKIVWR--GKDPLCSEIRQLLKTTQK-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: .*.:*.*****:* ::.: .:: : : . . . ***.:::: *.:. **:.*::**.::*:: ::: :* **. .* **:::*:*.* . : *:::::.: . . * :. **:. *:**: :* . .: . * *: .** .*:. * * **: : : . : :: * .:**:: ::.* :** : : * .. :*..* . :. *: . . *:::. :: : * . : :. *: :: :: : .: : :: ::.. : . ** :: * : . *: :*: : : : * :: *. : * * ::: ..::.:* * ::* : *:*:. :. * :* : ", "identical_positions": 73, "similar_positions": 164, "identity": "15.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1057", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R3S6-1", "uniprot_id": "EXOC1_MOUSE", "id": "Q8R3S6-1", "name": "Exocyst complex component 1", "aln": "-----------------------------------------------------MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVT---------------------------------------------TERPVQVKVVKVKKS-DKGD-FYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKVYKWVASSTAEKNAFISCIWKLNQRYLR-KKIDFVNVSSQLLEES-----------------------------------------------------------------------------------------VPSGENQSVAGGDEEAVDEYQELNAREEQDIEIMMEGCECAISN--------------AEAFAEKLSRELQVLDGANIQSIMASEKQVNTLMQLLDEALTEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVK-----LLSEIEFLVNHMDLAKGHIK---------------------------ALQEGDLVSSRGIEACTN-------------------------------------------------AADALLQCMNVALRPGHDMLLAVKQQQQRFSDLREHFARRLASHLNN--------VFVQQ-----------------------GHDQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDY-----------------------------------------------GKYEGLTKNYMDYLS-------------------RLYEREIKDFFEVAKMKMTGTSKESK-KFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSVQSSGSRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPL------------------------------CLAEQDFISKFFKLQQHQNMSASMTEAEDLDGGS-LLRQHSSGTLLPVSS----------EKDMIRQMMIKIFRCIEPELNNLIALGDKVDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEEVKISKKSKVGILPFVAEFEEFAGLAESIFKNAER-----------------------------RGDLDKAYTKLIRGVFINVEKVANESQKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNHFFEGVEARVAQG--IREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEEN------LLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZLJ5-1", "uniprot_id": "A0A8I5ZLJ5_RAT", "id": "A0A8I5ZLJ5-1", "name": "Exocyst complex component 1", "aln": "-----------------------------------------------------MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVT---------------------------------------------TERPVQVKVVKVKKS-DKGD-FYKRQIAWALRDLAVVDAKDAIKESPEFDLHFDKVYRWVASSIAEKNAFISCTWKLNQRYLR-KKIDFLNVSSQLLEELPK----------------------------------------------------------------------------------VAEESVPSGENQSVAGGDEEAVDEYQELNAREEQDIEIMMEGCECAISN--------------AEAFAEKLSRELQVLDGANIQSIMASEKQVNILMQLLDEALQEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVK-----LLSEIEFLVNHMDLAKGHVK---------------------------ALQDGDLASSRGIEACTN-------------------------------------------------AADALLQCMNVALRPGHDMLLAIRQQQQRFSELREHFARRLASHLNN--------VFVQQF-----TQALLQLYSRSYFLSVPGHDQSSTLAQHSAELTLPNHHPFHRDLLRYAKLMEWLKSTDY-----------------------------------------------GKYEGLTKNYMDYLS-------------------RLYEREIKDFFEVAKMKMTGTTKESK-KFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSVQSSGSRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPL------------------------------CLAEQDFISKFFKLQQHQNLSASMAEAEDLDGGS-LSRPQSSGSLLPVSS----------EKDMIRQMMIKIFRCIEPELNNLIALGDKVDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEEVKISKKSKVGILPFVAEFEEFAGLAESIFKSAER-----------------------------RGDLDKAYTKLIRGVFINVEKVANESQKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNHFFEGVEARVAQG--IREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEEN------LLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NV70-1", "uniprot_id": "EXOC1_HUMAN", "id": "Q9NV70-1", "name": "Exocyst complex component 1", "aln": "-----------------------------------------------------MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVT---------------------------------------------TERPVQVKVVKVKKS-DKGD-FYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQRYLR-KKIDFVNVSSQLLEES-----------------------------------------------------------------------------------------VPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISN--------------AEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVK-----LLSEIEFLVNHMDLAKGHIK---------------------------ALQEGDLASSRGIEACTN-------------------------------------------------AADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNN--------VFVQQ-----------------------GHDQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDY-----------------------------------------------GKYEGLTKNYMDYLS-------------------RLYEREIKDFFEVAKIKMTGTTKESK-KFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSVQSSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPL------------------------------CLAEQDFISKFFKLQQHQSMPGTMAEAEDLDGGT-LSRQHNCGTPLPVSS----------EKDMIRQMMIKIFRCIEPELNNLIALGDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEEVKISKKSKVGILPFVAEFEEFAGLAESIFKNAER-----------------------------RGDLDKAYTKLIRGVFVNVEKVANESQKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNHFFEGVEARVAQG--IREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEEN------LLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P2G2-1", "uniprot_id": "A0A8M9P2G2_DANRE", "id": "A0A8M9P2G2-1", "name": "Exocyst complex component 1", "aln": "-----------------------------------------------------MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVT---------------------------------------------TERPVQVKVVKVKKS-DKGD-FYKRQMAWELRDLTEVDAKDANKENPEFDLHFEKVYRWVASSTAEKNSFISCIWKLNQRYLR-KKVEFVNVSPQLLEELP-----------------------------------------------------------------------------------KAEESVPSGESQSVAGGDEDALDDYQELNAREEQDIEGMMEVCEYAISN--------------AEAFAEKLSRELQVLDGANIQSIMASEKQVNTLMQLLDQALAEVDTIEGKLLSYEEMLQSVKEQMDQISQSNRLIQISNTNNGK-----LLDEIQFLVNYMDLSKGHIK---------------------------ALQEGDLSSPKGIEACIN-------------------------------------------------ASEALSQCMNVALKPGHDKLMAIKQQQHLFSELRDTFARRLTNHLNN--------VFVHQFNHFSHFKMTIPQFYRSSCLSLPGHDQSSTLAQHTAELTLPKHSPLHRDLLRYAKLMEWLKNTQR-----------------------------------------------EKYEGLSRTYMDYMT-------------------RLYEREIKDFFEVAKIKMAGTSKDGKGKFATLPRKESALKQETESLHGSSGKLTGSTSSLNKLAVSSSNSRRSQSSSLLDMGNMSASDLDVADRTRFDKIFEQVLSELEPL------------------------------CLAEQDFISKFFKLQQIP----TLAQGENMDDSDGLMHSKPVSEHRHSIS----------EKDMVRMMMNKIFQSIETELNSLIALGDKIDSFNSLYMLVKMSHHVWTAENVDPASYLSTTLGNVLVTVKRNFDKCISAQIRQMEEVKISKKSKVGILPFVTGFEEFAKLAEAIFRNAER-----------------------------RGDLDKAYIKLMRAVFNNVEKVANESQKTPRDVVMMENFHHIFSTLSSLKISCLEAERKEAKQKYTEHLQSYVINSLGQPLEKLNHFFEGVEARVAQG--VREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYRKVDKHLCDEES------LLQVVWHSMQDEFIRQYKHFEGLINRCYPGSGITMEFTIQDMLEYFSSIAQSH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVG4-1", "uniprot_id": "EXOC1_DROME", "id": "Q9VVG4-1", "name": "Exocyst complex component 1", "aln": "-----------------------------------------------MLSIGAMANIKHTLQKELFLASGERLLSVVTVVKK-KDKKPCYLCVVTT---------------------------------------------APPVPVVTLCLIKQS-EQREGEYKRKRSWQLDEIKWVDGRNEQFETHEFDLQLEKLYKWYALNPHERQNFLAVLNRQIQKSVRGQRAEFRNVPAAWLSEKSPEKV-------------------------------------------------------------------------------ALGRAVQKTQHMDDEEDEEEEAQEFTALTDKEANELGKLFSECDFAIKD--------------AEQFIEQLSRELHDLDGANMQSVLASEQKVLKMMEHIDNAISEADKFENRLDSYEDILGHVKETMEKIGGKNAMIEIANNNNIK-----LMKELNKVISQLDLPHSQQQ---------------------------ALDEPDLKTANGRKAAIA-------------------------------------------------AAQCLQQAMNSDIDPALLRLEAVQDQRKRFEKWKQKFSATVSRFMNN--------LFIHLG------------------------NEIGDMQVTSTELTLPNHSNVHRELTPYTELMHWTKAMDR-----------------------------------------------KTYDGLMRVYTASLS-------------------KIYDRDVRNFFNLAKIQVTEKLRNSR---------------EDLDMSTSSRKSAVSTIPYGTLGIN-----RDQWG----------PGVETADRMRFDALLEKVLAELEPI------------------------------ALQEQLFCINFFQMDVISPTTKNTQTTLEMEKAVDMTQSIISGAVSPSGDGVPQKRIDRQINEDVRKLMMGLFGCLEPELVSFIQSFERVDSFYSLYVFVRLTQHVMSAQ--DTHSFLSMTFASALVQVKRSFDRFMQNQLLSIREAKLHKRSKA-ILPYVENFENFAQTAEGIFRKSDR-----------------------------RTDMEKWYLQLVNAIFEGIQLHSQEHPKTPVQVVRMENYHHMYALLAQLKVPGLDALKKEAKKCYNDALKAYVTQYFGRPLEKLNQFFEGVQLKVAQG--VKETEISYQMAFSKQELRKVIAQYPAREVKKGLENLYKKVEKHLSEEEN------LLQVVWHAMQEEFIAQYNYLEERIQKCYAGAMINLEFNIQDILAFFSDIARSH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33332-1", "uniprot_id": "SEC3_YEAST", "id": "P33332-1", "name": "Exocyst complex component SEC3", "aln": "MRSSKSPFKRKSHSRETSHDENTSFFHKRTISGSSAHHSRNVSQGAVPSSAPPVSGGNYSHKRNVSRASNSSQTSNFLAEQYERDRKAIINCCFSRPDHKTGEPPNNYITHVRIIEDSKFPSSRPPPDSKLENKKKRLLILSAKPNNAKLIQIHKARENSDGSFQIGRTWQLTELVRVEKDLEISEG--FILTMSKKYYWETNSAKERTVFIKSLITLYIQTFEGHVPELVNWDLSLFYLDERSYQRAVITNRPGSVSPIKSPTSNFTTNTTQSVGSVPFSAPTERTRRSETESVNPVSTPASVEYHAGMKSLNKAPYSSNSTLNEVNKRYELEQQQQQEEAELRRLEEQKRLQLQKENEMKRLEEERRIKQEERKRQMELEHQRQLEEEERKRQMELEAKKQMELKRQRQFEEEQRLKKERELLEIQRKQREQETAERLKKEEQEALAKKEEEEKSKRNKVDNESYTQEINGKVDNLLEDLNAVLAEETETTPTMQNGTYVPERSTARAHDQLKKPLNIAKVESLGGSDLNDSISLSDEIAGLNTSNLSGEDQDEKNDLSFEKGDEVRYSNNFEGEAPHVYHEVSIIQEEAPAVSQKLILPEENNESEALIESKEEIKTMENIDDEVLLEILTDINWSIEDDADSMIERIDLRLAETEYLFNQNLLSLQKIGPNIRPYEDKVNDECHRIIPTLSLFLMEMSNFSNDIENVESQDNGLQVESANKKLLWNTLDELLKTVSLDEISLNQLLECPIREKNLPWMENQLNLLLKAFQAIGSDGNEVEYNLREISGLKQRLQFYEKVTKIFLNRIVEEMQKKFSNIRGQDISHDQMIRILTTLLIFSPLILFCKEISQKSYQAIVENWNVSIQPVYMELWTKKISQLQGIDTNDEKMNELSLSQLLNEWDTFRKERKTNDINPVFKNSFSLLTECLQTMRQECIVYQNFVEVFFHISSKHNFEEYIKHFNDPDAPPILLDTVKVMQSDREAA------------VIETQLVSRIFQPIVTRLSSYFVELVKAEPTVAPALTFYLENEIKSLES-SNHEFLLSAVTRMYTQIKQVWSDNVEEQVLHFERISN-ATTNGEILPGILDLPVGLKNSEDLFQFAKRSMDIKDTDEGYESIELMNSSFRKLSIAATRSITHKEVNSSINPNLSDTAALNNDYMETISLLVNSNWLTEMLSMLNFNKDGIFDTSLQNVKKVFDVEKESYASFLLRDTMPKLTAFVYGVSNIIENTNNVNMTNPSRWAAYSRQNLENILLAYTSHEIETLVKRLHTHMVNDFGYHQENAINNVLCDKLWSCIQGQTVSLYLKLYTVIDKHYRG--TNIRFTKNDIISAFEEYKNA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ::: :::: .... * . . : :.:* * : ..: :::: :: : :: :* * :: *: * * * :.* * * : . *: *: : .. : :: * : : . : :: * :: ::: : . .: * .::. * : : * : .*::: : :: : : . . *: .*: :: . * : . : .:: : *:.::: :: . : :* ** . . . *. : : * ::: : :.. : . : :* :: : . :*. . :: ::: :. : : : * : : : ::*:: : *:: :: . : : * . : . : .::. *. : :.::* * :.: .: * * **::. : : : :: :* : ..* . : : :. : : . : :.: : : . .:* :. . :*: :. :. *: :.. . :: *** : : :* :*: :.* * .* . :. : . :: :* :* : .: : * * ::: ::.*: : ::*. : .: **. *. **. : : :. : * *:.:*:*.::: *..:*::. :..*: :: :.: .:. * : :* .:* : : * : * : * * .:.*. :*:: .. .: ", "identical_positions": 82, "similar_positions": 305, "identity": "6.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1058", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08679-1", "uniprot_id": "CISY2_YEAST", "id": "P08679-1", "name": "Citrate synthase, peroxisomal", "aln": "----------------MTVPYLNSNRNVASYLQS---NSSQEKTLKERFSEIYPIHAQDVRQFVKEHGKTKISDVLLEQVYGGMRGIPGSVWEGSVLDPEDGIRFRGRTIADIQKDLP-KAKGSSQPLPEALFWLLLTGEVPTQAQVENLSADLMSRS-ELPSHVVQLLDNLPKDLHPMAQFSIAVTALESESKFAKAYAQGIS-KQDYWSYTFEDSLDLLGKLPVIAAKIYRNVFKDGK-MGEVDPNADYAKNLVNLIGSKD---------------EDFVDLMRLYLTIHSDHEGGNVSAHTSHLVGSALSSPYLSLASGLNGLAGPLHGRANQEVLEWLFALKEEVNDDYSKDTIEKYLWDTLNSGRVIPGYGHAVLRKTDPRYMAQRKFAMDH---FPDYELFKLVSSIYEVAPGVLTEHGKTKNPWPNVDAHSGVLLQYYGLKESSFYTVLFGVSRAFGILAQLITDRAIGASIERPKSYSTEKYKELVKNIESKL-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P00890-1", "uniprot_id": "CISY1_YEAST", "id": "P00890-1", "name": "Citrate synthase, mitochondrial", "aln": "MSAILSTTSKSFLSRGSTRQCQNMQKALFALLNARHYSSASEQTLKERFAEIIPAKAEEIKKFKKEHGKTVIGEVLLEQAYGGMRGIKGLVWEGSVLDPEEGIRFRGRTIPEIQRELP-KAEGSTEPLPEALFWLLLTGEIPTDAQVKALSADLAARS-EIPEHVIQLLDSLPKDLHPMAQFSIAVTALESESKFAKAYAQGVS-KKEYWSYTFEDSLDLLGKLPVIASKIYRNVFKDGK-ITSTDPNADYGKNLAQLLGYEN---------------KDFIDLMRLYLTIHSDHEGGNVSAHTTHLVGSALSSPYLSLAAGLNGLAGPLHGRANQEVLEWLFKLREEVKGDYSKETIEKYLWDTLNAGRVVPGYGHAVLRKTDPRYTAQREFALKH---FPDYELFKLVSTIYEVAPGVLTKHGKTKNPWPNVDSHSGVLLQYYGLTEASFYTVLFGVARAIGVLPQLIIDRAVGAPIERPKSFSTEKYKELVKKIESKN-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8VHF5-1", "uniprot_id": "CISY_RAT", "id": "Q8VHF5-1", "name": "Citrate synthase, mitochondrial", "aln": "---------MALLTA---AARLLGAKNSSCLVLAARHASASSTNLKDILSNLIPKEQARVKTFRQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGYSIPECQKLLP-KAKGGEEPLPEGLFWLLVTGQMPTEEQVSWLSQEWAKRA-ALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGIN-RTKYWELIYEDCMDLIAKLPCVAAKIYRNLYREGSSIGAIDSKLDWSHNFTNMLCYTE---------------PQFTELMRLYLTIHSDHDGGNVSAHTSHLVGSALSDTYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYSCQREFALKH---LPKDPMFKLVAQLYKIVPNILLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLMKFVDSKSG---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CZU6-1", "uniprot_id": "CISY_MOUSE", "id": "Q9CZU6-1", "name": "Citrate synthase, mitochondrial", "aln": "---------MALLTA---ATRLLGAKNSSCLVLAARHASASSTNLKDVLSNLIPKEQARIKTFKQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGYSIPECQKMLP-KAKGGEEPLPEGLFWLLVTGQMPTEEQVSWLSREWAKRA-ALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGMN-RAKYWELIYEDCMDLIAKLPCVAAKIYRNLYREGSSIGAIDSRLDWSHNFTNMLGYTD---------------PQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYSCQREFALKH---LPKDPMFKLVAQLYKIVPNILLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLMKFVDSK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75390-1", "uniprot_id": "CISY_HUMAN", "id": "O75390-1", "name": "Citrate synthase, mitochondrial", "aln": "---------MALLTA---AARLLGTKNASCLVLAARHASASSTNLKDILADLIPKEQARIKTFRQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLP-KAKGGEEPLPEGLFWLLVTGHIPTEEQVSWLSKEWAKRA-ALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSESNFARAYAQGIS-RTKYWELIYEDSMDLIAKLPCVAAKIYRNLYREGSGIGAIDSNLDWSHNFTNMLGYTD---------------HQFTELTRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKH---LPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTEGLMKFVDSKSG---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVY5-1", "uniprot_id": "CISY_DANRE", "id": "Q7ZVY5-1", "name": "Citrate synthase, mitochondrial", "aln": "---------MSFLSISRLAPRLLSSKNAACVVVAARNASAS-TNLKDVLSDLVPKEQSRIKNFKQQYGKTSIGQITVDMVYGGMRGVKGLVYETSVLDPDEGIRFRGYSIPECQQLLP-KAPGGEEPLPEGLFWLLVTGQVPTEEQVSWLSKEWAKRA-ALPSHVVTMLDNFPTNLHPMSQFSAAITALNSESSFARAYSEGVN-KAKYWEFVYEDSMDLIAKLPCVAAKIYRNLYREGSSIGAIDSNLDWSHNFTNMLGYTE---------------PQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFSAAMNGLAGPLHGLANQEVLVWLTALQKELGGEVSDEKMRDYIWNTLKSGRVVPGYGHAVLRKTDPRYTCQREFALKH---LPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLVWSRALGFPLERPKSMSTDGLMALVGAKSG---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W401-1", "uniprot_id": "CISY_DROME", "id": "Q9W401-1", "name": "Probable citrate synthase, mitochondrial", "aln": "---------MSLYRIS--ARKLSEAQKLPNVGAYVRMIAADGKSLRDVLAAKVPQEQERVKNFRKQHGATKMGETTIDMMYGGMRGIKALVTETSVLDADEGIRFRGLSIPECQKVLP-AADGGTEPLPEGLFWLLLTGEVPTKSQVQQLSREWAERA-ALPQHVVTMLNNMPTTLHPMSQFAAAVTALNHDSKFAKAYSDGVH-KSKYWEYVYEDSMDLIAKLPVVAATIYCNTYRGGKGSRSIDSSLDWSANFVKMLGYDN---------------APFTELMRLYLTIHSDHEGGNVSAHTVHLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLVWLRKLQKEAGNNPSEEQLKEYIWKTLKSGQVVPGYGHAVLRKTDPRYTCQREFALKH---LPEDETFQLVSKIYKVVPPILTETGKVKNPWPNVDAHSGVLLQYYGMKEMNYYTVLFGVSRALGVLASLVWDRALGLPIERPKSFSTDLLVKMVQK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43635-1", "uniprot_id": "CISY3_YEAST", "id": "P43635-1", "name": "Citrate synthase 3, mitochondrial", "aln": "----------------MVQRLLPGAHICRRSFNSSAIIKSSALTLKEALENVIPKKRDAVKKLKACYGSTFVGPITISSVLGGMRGNQSMFWQGTSLDPEHGIKFQGLTIEECQNRLPNTGIDGDNFLPESMLWLLMTGGVPTFQQAASFRKELAIRGRKLPHYTEKVLSSLPKDMHPMTQLAIGLASMNKGSLFATNYQKGLIGKMEFWKDTLEDSLNLIASLPLLTGRIYSNITNEGHPLGQYSEEVDWCTNICSLLGMTNGTNSSNTCNLTSQQSLDFINLMRLYTGIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMGLAGPLHGLAAQEVVRFLIEMNSNISSIAREQEIKDYLWKILNSNRVIPGYGHAVLRKPDPRFTAMLEFAQKRPIEFENDKNVLLMQKLAEIAPKVLLEHGKSKNPFPNVDSASGILFYHYGIRELLFFTVIFGCSRAMGPLTQLVWDRILGLPIERPKSLNLEGLEALTKASNVNKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. .*:: : * . :: : :* * :. :. ***** . . : : **.:.**:*:* :* : *. ** . .. : ***.::***:** :** *. : : *. :* :. :*..:*. :***:*:: .::::: * ** * .*: : .:*. **.::*:..** ::. ** * . * . *: *: .:: : * :* *** ** **:******** ********..*** ::.: ******** * ***: :* :..: .: :..*:*. *::.:*:**********.***: . :** .: : . . *: : ::.* :* : ** ***:****: **:*: :**: * ::**:** :**:* *..*: .* :* .:***** . : :. ", "identical_positions": 149, "similar_positions": 146, "identity": "29.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1066", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V8F9-1", "uniprot_id": "HSDL2_RAT", "id": "Q4V8F9-1", "name": "Hydroxysteroid dehydrogenase-like protein 2", "aln": "MLPNTGKLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTTQRHPKLLGTIYTAAEEIEAAGGKALPCVVDVRDEQQINSAVEKAVERFGGIDILVNNASAISLTNTLETPTKRVDLMMSVNTRGTYLTSKACIPFLKKSKVAHILNLSPPLNLNPMWFKQHCAYTIAKYGMSMCVLGMAEEFRG-EIAVNALWPRTAIHTAAMDMLGGAGVESQCRKVDIIADAAYSIFKR-PKSFTGNFIIDENILKEEGIKDFDIYAITPG--HPLLPDFFLDEHPDAVMEEKESYDPVPEVKEEKLQLQEQPQLQEQPQLQEKPQLQEQPQLQEKPQLQEQPQLQEQPQLQEQPQQQPQLQEQPQLQEKPQLQEQPQQQEKPQPQQQPQQQPQQRPQQRPQPQPQPQPLLQSVLPPKPHFGAVEETFRIVKDSLSDEVVRATQAVYQFELSGEDGGTWFLDLKSKGGKVGHGEPSDRADVVMSMATEDFVKMFSGKLKPTMAFMSGKLKIKGNIALAIKLEKLMTHMNSRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2TPA8-1", "uniprot_id": "HSDL2_MOUSE", "id": "Q2TPA8-1", "name": "Hydroxysteroid dehydrogenase-like protein 2", "aln": "MLPNTGKLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTTQKHPKLLGTIYTAAEEIEAAGGTALPCVVDVRDEQQINSAVEKAVEKFGGIDILVNNASAISLTNTLDTPTKRVDLMMNVNTRGTYLTSKACIPFLKKSKVGHILNLSPPLNLNPLWFKQHCAYTIAKYGMSMCVLGMAEEFRG-EIAVNALWPRTAIHTAAMDMLGGSGVENQCRKVDIIADAAYSIFKR-PKSFTGNFIIDENILKEEGIKNFDVYAIAPG--HPLLPDFFLDEHPDAVMEEKESNDSVPEVKEEKLQLQEESQLQKQPQLQEQPQLQEKPQLQEKPQLQEQPQLQEKPQLQEQPQQR----EQPQLQ------------------------------QQPRPRQQPQPFVQSMLPQKPHFGAVEETFRIVKDSLSDEVVRATQAVYQFELSGEDGGTWFLDLKSKGGKVGHGEPSDRADVVMSMATDDFVKMFSGKLKPTMAFMSGKLKIKGNIALAIKLEKLMTQMNSRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6YN16-1", "uniprot_id": "HSDL2_HUMAN", "id": "Q6YN16-1", "name": "Hydroxysteroid dehydrogenase-like protein 2", "aln": "MLPNTGRLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKALPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRGTYLASKACIPYLKKSKVAHILNISPPLNLNPVWFKQHCAYTIAKYGMSMYVLGMAEEFKG-EIAVNALWPKTAIHTAAMDMLGGPGIESQCRKVDIIADAAYSIFQK-PKSFTGNFVIDENILKEEGIENFDVYAIKPG--HPLQPDFFLDEYPEAVSKKVESTGAVPEFKEEKLQLQ----------------------------------------------------------------------------------------------------------PKPRSGAVEETFRIVKDSLSDDVVKATQAIYLFELSGEDGGTWFLDLKSKGGNVGYGEPSDQADVVMSMTTDDFVKMFSGKLKPTMAFMSGKLKIKGNMALAIKLEKLMNQMNARL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P5L8-1", "uniprot_id": "HSDL2_DANRE", "id": "Q6P5L8-1", "name": "Hydroxysteroid dehydrogenase-like protein 2", "aln": "MLQNTGKLAGCTIFITGASRGIGKAIALKAAQDGANVVIAAKTADPHPKLPGTIYTAAAEIEAAGGKALPCIVDVRDEKQINDAVEQAVEKFGGIDILVNNASAINLTGTLQTPMKKADLMLGINLRGTYLTSKLCIPHLLKSKNPHILNLSPPLNLNPIWFKNHTAYTIAKYGMSMCVLGMAEEFRG-SIAVNALWPKTAIQTAAMDMLGGSEVGKQCRKVEIMADAAYAIFKQ-PTSFTGQFVIDEDILKKEGIKDFDVYAVEPG--HPLLPDFFLDGQPEDLVKHMEAHGATPAFTTAKADPV-------------------------------------------------------------------------------------------------------------AAGPVSEMFNTIRGIISPEMVKTTQGVYKFNLAGEHAGVWYLDLKNDAGSAGNGEPPVKADVVMSMDSEDFVKMFGGKLKPTMAFMSGKLTIKGDMGLAIKLEKMMAMMKSKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VB10-1", "uniprot_id": "Q9VB10_DROME", "id": "Q9VB10-1", "name": "Hydroxysteroid dehydrogenase-like protein 2", "aln": "-MINTGKLAGRTLFITGASRGIGKEIALKAARDGANIVVAAKTAEPHPKLPGTIYSAAEEIEKAGGKAYPCVVDVRDEQQVRSAVEAAVAKFGGIDIVINNASAISLTNTPDTDMKRYDLMHNINTRGTFLVSKVCLPYLKKSNHAHILNISPPLSMKPKWFGPHVAYTMAKYGMSMCVLGMAAEFKDEGISVNALWPRTAIHTAAIEMLTGPDSAKWSRKPEIMADAAYAILTREPRQSTGQFFVDDEVLESAGITDLTEYACFRENADKLMVDFFVEEKGAPVENEAAAEDAAAPASGGDVKIP-------------------------------------------------------------------------------------------------------------------QLFRKIESLLSPEIVSKTQAVFQFNISGAEQGTWFLDLKNGSGSCGAGTPTAAPDATLTMNSKNFFDMFSGKLKAAPAYMTGKLKISGDFQKALKLEKLMKALKSKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ***:*** *:*********** ******:****:*:****:: **** ****:** *** .**.* **:******:*: *** *: :******::******.**.* :* *: *** .:* ***:*.** *:*.* **: ****:****.::* ** * ***:******* ***** **:. *:******:***:***::** *. . .** :*:*****:*: : * . **:*.:*:::*:. ** :: ** . * ***:: : :. : .... . . . : *. :.. :* ::* **.:: *:::* . *.*:****. .*. * * *. .*..::* :.:*..**.****.: *:*:***.*.*:: *:****:* ::::*", "identical_positions": 202, "similar_positions": 120, "identity": "38.26%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1067", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZSK5-1", "uniprot_id": "SETD6_RAT", "id": "D3ZSK5-1", "name": "N-lysine methyltransferase SETD6", "aln": "MAAPAKRARVS---DASPLAAPCPVPRAAARVPLPLPAGPSGHEPESDAVAGFLRWCTRVGLELSP-KVLVSRQGTVAGYGMVARESVQPGELLFAVPRSALLSPHTCSISDLLERERGALQSLSG-WVPLLLALLHELQAP--ASPWSPYFALWPELGRLEHPMFWPEEERLRLLKGTGVPEAVEKDLVNIRSEYYSIVLPFMEAHSDLFSPTVRSLELYRQLVALVMAYSFQEPLE-----EEEDEKEPN--------SPLMVPAADILN-HIANHNANLEYSAEYLRMVATQPILKGHEIFNTYGQMANWQLIHMYGFAEPYPNNTDDTADIQMVAVREAALQGTEDETERL-LLCERWDFLCKQELVGEEGAFVIGREEVLTEEELATTLKVLCMPAEEFRDYK--ERAGWGEEETEDGS-----LAITNIPKLQESWKRLLRDSVLLTLQTYATDLKTEQDLLSNKEVYAKLSWREQQALQVRYGQKMILHRLLELTS-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWY3-1", "uniprot_id": "SETD6_MOUSE", "id": "Q9CWY3-1", "name": "N-lysine methyltransferase SETD6", "aln": "MAAPAKRARVS---GGSPLVAPCPSPR-AARAPLPLPAGSSGGEPEGDAVAGFLRWCRRVGLELSP-KVTVSRQGTVAGYGMVARESVRAGELLFAVPRSALLSPHTCSISGLLERERGALQSLSG-WVPLLLALLHELQAP--ASPWSPYFALWPELGRLEHPMFWPEEERLRLLKGTGVPEAVEKDLVNIRSEYYSIVLPFMEAHSDLFSPSVRSLELYQQLVALVMAYSFQEPLE-----EDDDEKEPN--------SPLMVPAADILN-HIANHNANLEYSADYLRMVATQPILEGHEIFNTYGQMANWQLIHMYGFAEPYPNNTDDTADIQMVTVRDAALQGTKDETEKL-LVCERWDFLCKQEMVGEEGAFVIGCEEVLTEEELATTLKVLCMPAEEFRDYK--ERAGWGEEETEDDS-----LAITDIPKLQESWKRLLRNSVLLTLQTYTTDLKTDQDLLSNKEAYATLSWREQQALQVRYGQKMILHRVLELTN-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TBK2-1", "uniprot_id": "SETD6_HUMAN", "id": "Q8TBK2-1", "name": "N-lysine methyltransferase SETD6", "aln": "MATQAKRPRVAGPVDGGDLDPVACFLSWCRRVGLELSPKVS--ERAGGRRT---RGGARAALTSPPAQVAVSRQGTVAGYGMVARESVQAGELLFVVPRAALLSQHTCSIGGLLERERVALQSQSG-WVPLLLALLHELQAP--ASRWRPYFALWPELGRLEHPMFWPEEERRCLLQGTGVPEAVEKDLANIRSEYQSIVLPFMEAHPDLFSLRVRSLELYHQLVALVMAYSFQEPLE-----EEEDEKEPN--------SPVMVPAADILN-HLANHNANLEYSANCLRMVATQPIPKGHEIFNTYGQMANWQLIHMYGFVEPYPDNTDDTADIQMVTVREAALQGTKTEAERH-LVYERWDFLCKLEMVGEEGAFVIGREEVLTEEELTTTLKVLCMPAEEFRELK--DQDGGGDDKREEGS-----LTITNIPKLKASWRQLLQNSVLLTLQTYATDLKTDQGLLSNKEVYAKLSWREQQALQVRYGQKMILHQLLELTS-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803K4-1", "uniprot_id": "SETD6_DANRE", "id": "Q803K4-1", "name": "N-lysine methyltransferase setd6", "aln": "MATEAKRPKTGD--EKSVLEPLNNFLLWCESVQLTLS-----------------------------DKVYLSKEGTAAEYGMLAKEDIEEGHVLFTIPREALLHQGTTKVKKVLEEGKKCLESASG-WVPLLLSLMYEYTSS--TSHWKPYLSLWPDFRTLDQPMFWSEEECDKLLKGTGIPESVITDLRKLQDEYNSVVLPFMKSHPDLWDPEKHNLELYKSLVAFVMAYSFQEPVEDDDEDEEDDEKKPN--------LPMMVPMADMLN-HISKHNANLEYTPECLKMVSIRRIGKGEEVFNTYGQMANWQLLHMYGFAEPFPNNINETADIKMASVYKAAAQVARSEANQQ-LLEDKWKMLCEMEVVGEKGVFIFGQSGSLTYHELYTTLKVLCMSSQIFEDFR--ENEGWEEDDEDDDDKMEQDLSFEGLASLSVEWKRLLCVAATETLDSYNEDVETDRRLMEDQRALAELSSRERRALYVRLGQKNILQRIQQLTKPAS--------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12504-1", "uniprot_id": "RKM4_YEAST", "id": "Q12504-1", "name": "Ribosomal lysine N-methyltransferase 4", "aln": "MDDFSR-----------DTENFVCWLKTTAEIEVSPK------------------------------IEIKDLCCDNQGRAVVATQKIKKDETLFKIPRSSVLSVTTSQLIKDYPSLKDKFLNETGSWEGLIICILYEMEVLQERSRWAPYFKVWNKPSDMNALIFWDDNE-LQLLKPSLVLERIGKKEAKEMHERIIKSIKQIGGEFSRVATS-FEFDNFAYIASIILSYSFDLEMQDSSVNENEEEETSEEELENERYLKSMIPLADMLNADTSKCNANLTYDSNCLKMVALRDIEKNEQVYNIYGEHPNSELLRRYGYVE-WDGSKYDFGEVLLENIVEALKETFETNTEFLDRCIDILRNNANIQEFLEGEEIVLDSYDCYNNGELLPQLILLVQILTILCQIPGLCKLDIKAMERQVERIVKKCLQLIEGARATTNCSATWKRCIMKRLADYPIKKCVSIEKPSKGNSLTREELRDVMARRVLKSEIDSLQVCEETIDKNYKVIPDEKLLTNILKRKLTEEEKSSVKRPCVKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: : . .::* :.:. .. ** :** ::* * .: : : . :* * *::.:::* * * **: :* . :: :** ::* **: : : * : .. : * : : .. . .:: : :.:::::***: :: *:::*: .: *:* **:** . :: **** * .: *:**: : * :..:::* **: .* :*:: **:.* : .. : .:: : : .* : . ::: : .: : . * :::. . ** . * :* : : . . . : * : . . . * * . .. .. . : . *: * * .: *: : . ", "identical_positions": 65, "similar_positions": 142, "identity": "12.08%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1069", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2Q3-1", "uniprot_id": "BKGD_RAT", "id": "Q5U2Q3-1", "name": "Beta-keto L-gulonate decarboxylase", "aln": "MACT----------EFSFHVPSLEELAEVLQKGLKDNFAHVQVSVVDCPDLTKEPFTFPVKGICGQTRIAEVGGVPYLLPLVNKKKVYDLNEIAKEIKLPG-AFILGAGAGPFQTLGFNSEFMPIVQTASEHHQPVNGSYFARANPADGKCLLEKYSQKYPDFGCALLANLFASEGQPGKVIEVQAKKRTGEHNFVSCMRQTLEKHYGDKPVGMGGTFLVQKGKVKAHIMPAEFSSCSLNSDEAVNQWLNFYEMKAPLVCLPVFVSKDPGLDLRLEHTHFFSHHGEGGHYHYDTTPDTVEYLGYFSPAQFLYRIDQPKETHAFGRD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91V76-1", "uniprot_id": "BKGD_MOUSE", "id": "Q91V76-1", "name": "Beta-keto L-gulonate decarboxylase", "aln": "MACS----------EFSFHMPSLEELAEVLQKGLTDNFADVQVSVVDCPDLTKEPFTFPVRGICGQTRIAEVGGVPYLLPLVNKKKVYDLNEIAKVIKLPG-AFILGAGAGPFQTLGFNSEFMPIVQTASEHNQPVNGSYFAHKNPADGACLLEKYSQKYHDFGCALLANLFASEGQPGKVIEVQAKRRTGELNFVSCMRQTLEEHYGDKPVGMGGTFIVQKGKVKAHIMPAEFSSCPLNSDEAVNKWLHFYEMKAPLVCLPVFVSKDPGLDLRLEHTHFFSHHGEGGHYHYDTTPDTVEYLGYFSPAQFLYRIDQPKETHAFGRD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0W9-1", "uniprot_id": "BKGD_HUMAN", "id": "Q9H0W9-1", "name": "Beta-keto L-gulonate decarboxylase", "aln": "MACA----------EFSFHVPSLEELAGVMQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLLPLVNQKKVYDLNKIAKEIKLPG-AFILGAGAGPFQTLGFNSEFMPVIQTESEHKPPVNGSYFAHVNPADGGCLLEKYSEKCHDFQCALLANLFASEGQPGKVIEVKAKRRTGPLNFVTCMRETLEKHYGNKPIGMGGTFIIQKGKVKSHIMPAEFSSCPLNSDEEVNKWLHFYEMKAPLVCLPVFVSRDPGFDLRLEHTHFFSRHGEGGHYHYDTTPDIVEYLGYFLPAEFLYRIDQPKETHSIGRD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NWE0-1", "uniprot_id": "CK054_DANRE", "id": "Q6NWE0-1", "name": "Ester hydrolase C11orf54 homolog", "aln": "MDNSGK------TEKFQLHVPNLEELCQVLESGLNKNFSDVKVSVTDCPDLTQQPFGFPVKGLCGKPRITDVGGVPNLIPLVKLDKVYNMNSVSKEVELPG-AFILGAGAISFKTAGINGELMPLVLTEAEGRSAVNASYFSSINPEDGKCLQEKYSDRFDDCDFGLLANLYACEGKPGKVIEVKACRRTGEDSLVSCMRKTMAEHYGEKSVALGGTFIIQKGKAKIHIMPREFSVCPLNTDEDVNNWLRHFEVSAPLIFQTVMISRDPGLDLRVEHTHGFSHHGEGGHYYTDTTPNTVEYLGYFLPAETVYRIDRPTETHNVGRD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0J9-1", "uniprot_id": "Q9W0J9_DROME", "id": "Q9W0J9-1", "name": "DUF1907 domain-containing protein", "aln": "MSQNQLSTEQLLFEEKPLYVPPLSELQNVIQGALAANFANVNVSVGPCPDLKAKQFGLVESGLGGKPTLLEAGGPPFLLPLVQRDKLYNIAEITRKIQGPGTVFAVGAGAGPWPIRGSNCEGI-FNLSVNEKDELTNGSYTATVRGEQEECVLEKIP--HTEPRCALLLNLFLSQGKPGQVLKITAKQRTGEQNFIECIRKGLENHYGDKVVGLGGIFLIKKGAAHQHVM-RDFSKTPINSDEEVNEWLKFYEMPAQLNAVGTLVTKEHDLDLRLQHFHSFSFSNWGGHYHYDTTPDIVEYEAYLNVAERVVRVDKPVATHKVGRD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : :::* *.** *:: .* **:.*:*** ****. : * : *: *:. : :.** * *:***: .*:*:: .::: :: ** .* :**** .: * * * : . : * .*.** : . : *: ** . : .** **: .:*:**:*::: * :*** .:: *:*: : :***:* :.:** *:::** .: *:* :** .:*:** **:**..:*: * * .::::: .:***::* * ** . ****: ****: *** .*: *: : *:*:* ** .***", "identical_positions": 111, "similar_positions": 103, "identity": "34.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1072", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZM21-1", "uniprot_id": "D3ZM21_RAT", "id": "D3ZM21-1", "name": "", "aln": "MALPVPRLSIPAALALGSAALGAAFATGLFLGKRWPPWGYRRHQRLLPPQDNPLWQYLLSRSMREHPALRSLRLLTLEQPQGDSMMTCEQAQLLANLARLIKAKKALDLGTFTGYSALALALALPEAGRVVTCEVDAEPPKLGRPLWKQAEVEQKIDLRLQPALQTLDELLAAGEAGTFDIAVVDADKENCTAYYERCLQLLRPGGVLAVLRVLWRGEVLQPQPKNKAVECVRNLNERILRDARVYISLLPLDDGLSLAFKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BIG7-1", "uniprot_id": "CMTD1_MOUSE", "id": "Q8BIG7-1", "name": "Catechol O-methyltransferase domain-containing protein 1", "aln": "MAQPVPRLSIPAALALGSAALGAAFATGLLLGKRWPPWGSRRQERLLPPEDNPLWQYLLSRSMREHPALRSLRLLTLEQPQGDSMMTCEQAQLLANLARLIKAKKALDLGTFTGYSALALALALPEAGRVVTCEVDAEPPKLGRPMWKQAEVEQKIDLRLQPALQTLDELLAAGEAGTFDIAVVDADKENCTAYYERCLQLLRPGGVLAVLRVLWRGEVLQPQPRNKTVECVRNLNERILRDARVYISLLPLDDGLSLAFKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86VU5-1", "uniprot_id": "CMTD1_HUMAN", "id": "Q86VU5-1", "name": "Catechol O-methyltransferase domain-containing protein 1", "aln": "MTQPVPRLSVPAALALGSAALGAAFATGLFLGRRCPPWRGRREQCLLPPEDSRLWQYLLSRSMREHPALRSLRLLTLEQPQGDSMMTCEQAQLLANLARLIQAKKALDLGTFTGYSALALALALPADGRVVTCEVDAQPPELGRPLWRQAEAEHKIDLRLKPALETLDELLAAGEAGTFDVAVVDADKENCSAYYERCLQLLRPGGILAVLRVLWRGKVLQPPKGDVAAECVRNLNERIRRDVRVYISLLPLGDGLTLAFKI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NUZ9-1", "uniprot_id": "A0A8M1NUZ9_DANRE", "id": "A0A8M1NUZ9-1", "name": "", "aln": "-----MLCTFSLILALTGLCRSALIS--------------KSHE-----GDDPLLQYVVNNSLREHPVLTKLRLRTMEDARNVMMVASEQAQLMANLAKLIEANKTIEIGLYTGYNALSLALVVPENGRVVACEINEDYVKIGKPFFAEAGVENKIDIRLKPAVETLDELLSAGEAGMYDFVFIDADKKNYETYYEKSLQLVRKGGIVAIDNVLWGGRVINPAEDDLSSQAIDKLNKKLHKDERIDLSMLTVGDGLTLAIKR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. *** . . .* :: : .: *. * **::..*:****.* .*** *:*:.:. *::.*****:****:**:*:*::::* :***.**:***.:* ****:**:: : ::*:*:: :* .*:***:**:**::******:***** :*...:****:* :***:.***:* **::*: .*** *.*::* : : :.: :**::: :* *: :*:*.:.***:**:* ", "identical_positions": 105, "similar_positions": 92, "identity": "40.08%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1074", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P02654-1", "uniprot_id": "APOC1_HUMAN", "id": "P02654-1", "name": "Apolipoprotein C-I", "aln": "MRLFLSLPVLVVVLSIVLEGPAPAQGTPDVSSAL-DKLKEFGNTLEDKARELISRIKQSELSAKMREWFSETFQKVKEKLKIDS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QDI1-1", "uniprot_id": "E9QDI1_DANRE", "id": "E9QDI1-1", "name": "", "aln": "MKLYLAAAVLMLVLAVHTAEAQEEPTLEQHFTKFGTQMKEIAEDLADKTKTAFQNIEQSELGTKTRNWFNDQYEKLKQKMTETFN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*:*: .**::**:: . : : : ::**:.: * **:: :..*:****.:* *:**.: ::*:*:*:. ", "identical_positions": 24, "similar_positions": 34, "identity": "28.24%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1077", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P22449-1", "uniprot_id": "HNF4A_RAT", "id": "P22449-1", "name": "Hepatocyte nuclear factor 4-alpha", "aln": "----------------MRLSKT-LADMDMAD--------YSAALDPAYTTLEFENVQV----------LTMGNDT----------------------SPSEGANLN-----SSNSLGVS--------------------ALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKE-----AVQNERDRISTRRSSYEDSSLP---SINALLQAEVLSQQITS---PISGINGDIRAKKIANITDVCESMKEQLLVLVEWAKYIPAFCELLLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELA-----EMSRVSIRILDELVLPFQELQIDDNEYACLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSASD------APHAHHPLHPHLMQEHMGTNVIVANTMPSHLSNGQ-------------------MCEWPRPRGQAATPETPQPSPPSGSGSESYKLLPGAITTIVKPPSA--------------------------------------IPQPTITKQEAI--------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49698-1", "uniprot_id": "HNF4A_MOUSE", "id": "P49698-1", "name": "Hepatocyte nuclear factor 4-alpha", "aln": "----------------MRLSKT-LAGMDMAD--------YSAALDPAYTTLEFENVQV----------LTMGNDT----------------------SPSEGANLN-----SSNSLGVS--------------------ALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKE-----AVQNERDRISTRRSSYEDSSLP---SINALLQAEVLSQQITS---PISGINGDIRAKKIANITDVCESMKEQLLVLVEWAKYIPAFCELLLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELA-----EMSRVSIRILDELVLPFQELQIDDNEYACLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSASD------APHTHHPLHPHLMQEHMGTNVIVANTMPSHLSNGQ-------------------MCEWPRPRGQAATPETPQPSPPSGSGSESYKLLPGAITTIVKPPSA--------------------------------------IPQPTITKQEAI--------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41235-1", "uniprot_id": "HNF4A_HUMAN", "id": "P41235-1", "name": "Hepatocyte nuclear factor 4-alpha", "aln": "----------------MRLSKT-LVDMDMAD--------YSAALDPAYTTLEFENVQV----------LTMGNDT----------------------SPSEGTNLN-----APNSLGVS--------------------ALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKE-----AVQNERDRISTRRSSYEDSSLP---SINALLQAEVLSRQITS---PVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELA-----EMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSD------APHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQ-------------------MCEWPRPRGQAATPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSA--------------------------------------IPQPTITKQEVI--------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PEX6-1", "uniprot_id": "A0A8M9PEX6_DANRE", "id": "A0A8M9PEX6-1", "name": "", "aln": "----------------MRLSKP-LVDMEMAD--------YSEALDPAYTTLEFENMQV----------LAMSTDS----------------------SPQESANMN-----AANHLGAG--------------------TLCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFNRQCIVDKDKRNQCRYCRLKKCFRAGMKKEVISSSAVQNERDRISTRRSSYEDSSLP---SINALIQADVLSRQISS---PGPILNGDIRTKKVAAIMDVCESMKQQLLVLVEWAKYIPAFCDLPLDDQVALLRAHAGEHLLLGAAKRSMMYKDILLLGNDHIIPRNCPEL------EVSRVAVRILDELVLPFQDLQIDDNEYACLKAIVFFDPDAKGLSDPSKIKRMRYQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMAKIDNLLQEMLLGGSANE------APHAHHSLHPHLVQEHLSNNVIVTANMATPLHNG-----------------------------QMSTPETPIPSPPTASGSDHYKMASGVIATVPKQPSS--------------------------------------IPQPTITKQEAI--------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P49866-1", "uniprot_id": "HNF4_DROME", "id": "P49866-1", "name": "Transcription factor HNF-4 homolog", "aln": "MMKHPQDLSVTDDQQLMKVNKVEKMEQELHDPESESHIMHADALASAYPAASQPHSPIGLALSPNGGGLGLSNSSNQSSENFALCNGNGNAGSAGGGSASSGSNNNNSMFSPNNNLSGSGSGTNSSQQQLQQQQQQQSPTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFARNCVVDKDKRNQCRYCRLRKCFKAGMKKE-----AVQNERDRISCRRTSNDDPDPGNGLSVISLVKAENESRQSKAGAAMEPNINEDLSNKQFASINDVCESMKQQLLTLVEWAKQIPAFNELQLDDQVALLRAHAGEHLLLGLSRRSMHLKDVLLLSNNCVITRHCPDPLVSPNLDISRIGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNEPHRIKSLRHQILNNLEDYISDRQYESRGRFGEILLILPVLQSITWQMIEQIQFAKIFGVAHIDSLLQEMLLGGELADNPLPLSPPNQSNDYQSPTHTGNMEGGNQVNSSLDSLATSGGPGSHSLDLEVQHIQALIEANSADDSFRAYAASTAAAAAAAVSSSSSAPASVAPASISPPLNSPKSQHQHQQHATHQQQQESSYLDMPVKHYNGSRSGPLPTQHSPQRMHPYQRAVASPVEVSSGGGGLGLRNPADITLNEYNRSEGSSAEELLRRTPLKIRAPEMLTAPAGYGTEPCRMTLKQEPETGY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::.* :: * :: ** .**.: . : : * :...: *....:* * . * *. . ::********************************* *:*** *:*:**************:***:****** ********** **:* :*.. *: :*::*: *:* .: . :* *: *:.* * *******:***.****** **** :* ******************* ::*** **:***.*: ::.*:**: ::**:. **:**** :::: ***.*:* :**::****:****.:* :** :* *: .*****.****:*******:**:**.************** *:**:*:**.*********. : .*: : :. :: . * .: : .* ::. :. .:. .*.* .: .. ::. : .: ** . *..: ", "identical_positions": 236, "similar_positions": 131, "identity": "33.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-108", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3X9K3-1", "uniprot_id": "BIG1_MOUSE", "id": "G3X9K3-1", "name": "Brefeldin A-inhibited guanine nucleotide-exchange protein 1", "aln": "-------------------------MYE-GKKTKNMFLTRALEKILADKEVKKAHHSQLRKACEVALEEIKVETEKQSPPHGEAKAGSGTLPPVKS-KTNFIEADKYFLPFELACQSKCPRIVSTSLDCLQKLIAYGHLTGRAPDSTTPGKKLIDRIIETICGCFQGPQ---TDEGVQLQIIKALLTAVTSQHIEIHEGTVLQAVRTCYNIYLASKNLINQTTAKATLTQMLNVIFAR---MENQAL------------------QEAKQMERERHRQQQHLLQSPVSHHEPESPHLRYLPPQTVDHINQEHEGDLEPQTHDVDKS--LQDDTEPENGSDISSAENEQTEADQATAAETLSKN---DILYDG---DYEEKPLDIVQSIVEEMVNIIVGDMGEGMAISASTEGNTGTVED-------------------------------------------GSDSENIQANGIPGTPISVAYTPSLPDDRLSVSSNDTQESGNSSGPSPGAKFSHILQKDAFLVFRSLCKLSMKPLSDGPPDPKSHELRSKILSLQLLLSILQNAGPVFRTN---------EMFINAIKQYLCVALSKNGVSSVPEVFELSLSIFLTLLSNFKTHLKMQIEVFFKEIFLYILETSTSSFDHKWMVIQTLTRICADAQSVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRGSQ---------------------------------------ELGMSNVQELSLRKKGLECLVSILKCMVEWSKDQYVNPNSQTTLGQEKPSEQEISEVKHPETINRYGSLNSLESTSSSGIG-----SYSTQMSGTDNPEQFEVLKQQKEIIEQGIDLFNKKPKRGIQYLQEQGMLG-TTPEDIAQFLHQEERLDSTQVGEFLGDNDKFNKEVMYAYVDQHDFSGKDFVSALRLFLEGFRLPGEAQKIDRLMEKFAARYLECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSK-DLPEEYLSAIYNEIAGKKISMK-ETKELTIPTKSTKQN--------VASEKQRRLLYNLEMEQMAKTAKALMEAVSHVQAP---FTSATHLEHVRPMFKLAWTPFLAAFSVGLQDCDDTEVASLCLEGIRCAIRIACIFSIQLERDAYVQALARFTLLTVSSGITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKPRYISGTVRGREGSLTGTKDQAPDEFVGLGLVGGNVDWKQIASIQESIGETSS---------QSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELLS---TTHPRMFSLQKIVEISYYNMGRIRLQWSRIWEVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKRNRSPTIRDMVVRCIAQMVNSQAANIRSGWKNIFSVFHLAASDQDESIVELAFQTTGHIVTLVFEKHFPATIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRHCAKYVSDRPQAFKEYT----SDDMSVAPEDRVWVRGWFPILFELS-CIINRCKLDVRTRGLTVMFEIMKTYGHTYEKHWWQDLFR-IVFRIFDNMKLPEQQ------TEKAEWMTTTCNHALYAICDVFTQYLEVLSDVLLDDIFAQLYWCVQQDNEQLARSGTNCLENVVILNGEKFTLEIWDKTCNCTLDIFKTTIPHALLTWRPTSGEAEPPSPSAVSEKPLDAISQKSVDIHDSIQPRSSDNRQQAPLVSVSTVS--EEVSKVKSTAKFPEQKLFAALLIKCVVQLELIQTIDNIVFFPATSKKEDAENLAAAQRDAVDFD---------VRVDTQDQGMYRFLTSQQLFKLLDCLLESHRFAKAFNSNNEQRTALWKAGFKGKSKPNLLKQETSSLACGLRILFRMYMDESRVSAWEEVQQRLLNVCREALSYFLTLTS---ESHREAWTNLLLLFLTKVLKISDSRFKAHASFYYPLLCEIMQFDLIPELRAVLRRFFLRIGIVFQISQPPEQELGINRQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A631-1", "uniprot_id": "BIG1_RAT", "id": "D4A631-1", "name": "Brefeldin A-inhibited guanine nucleotide-exchange protein 1", "aln": "-------------------------MYE-GKKTKNMFLTRALEKILADKEVKKAHHSQLRKACEVALEEIKVETEKQSPPHGEAKAGSGTLPPVKS-KTNFIEADKYFLPFELACQSKCPRIVSTSLDCLQKLIAYGHLTGSAPDSTTPGKKLIDRIIETICGCFQGPQ---TDEGVQLQIIKALLTAVTSQHIEIHEGTVLQAVRTCYNIYLASKNLINQTTAKATLTQMLNVIFAR---MENQAL------------------QEAKQMERERHRQQHHLLQSPVSHHEPESPHLRYLPPQTVDHIAQEQEGDLDPQTHDVDKS--LQDDIEPENGSDISSAENEQTEADQATAAETLSKD---DVLCDG---ECEEKPQDIVQSIVEEMVDIIVGDMGEGTAVSASADGNAGAVED-------------------------------------------GSDSENVQANGIPGTPISAAYTPSLPDDRLSVSSNDTQESGNSSGPSPGAKFSHILQKDAFLVFRSLCKLSMKPLSDGPPDPKSHELRSKILSLQLLLSILQNAGPVFRTN---------EMFINAIKQYLCVALSKNGVSSVPEVFELSLSIFLTLLSNFKTHLKMQIEVFFKEIFLYILETSTSSFDHKWMVIQTLTRICADAQSVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRGSQ---------------------------------------ELGMSNVQELSLRKKGLECLVSILKCMVEWSKDQYVNPNSQTTLGQEKPSEQEISEIKHPETINRYGSLNSLESTSSSGIG-----SYSTQMSGTDNPEQFEVLKQQKEIIEQGIDLFNKKPKRGIQYLQEQGMLG-TTPEDIAQFLHQEERLDSTQAGEFLGDNDKFNKEVMYAYVDQHDFSGKDFVSALRLFLEGFRLPGEAQKIDRLMEKFAARYLECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSK-DLPEEYLSAIYNEIAGKKISMK-ETKELTIPTKSTKQN--------VASEKQRRLLYNLEMEQMAKTAKALMEAVSHVQAP---FTSATHLEHVRPMFKLAWTPFLAAFSVGLQDCDDTDVASLCLEGIRCAIRIACIFSIQLERDAYVQALARFTLLTVSSGITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKPRYISGTVRGREGSLTGTKDQAPDEFVGLGLVGGNVDWKQIASIQESIGETSS---------QSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELLS---TTHPRMFSLQKIVEISYYNMGRIRLQWSRIWEVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKRNRSPTIRDMVVRCIAQMVNSQAANIRSGWKNIFSVFHLAASDQDESIVELAFQTSGHIVTLVFEKHFPATIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRHCAKYVSDRPQAFKEYT----SDDMNVAPEDRVWVRGWFPILFELS-CVINRCKLDVRTRGLTVMFEIMKTYGHTYEKHWWQDLFR-IVFRIFDNMKLPEQQ------TEKAEWMTTTCNHALYAICDVFTQYLEVLSDVLLDDIFAQLYWCVQQDNEQLARSGTNCLENVVILNGEKFTLEIWDKTCNCTLDIFKTTIPHALLTWRPTSGEAAPPSPSAMSEKQLDAISQKSVDIHDSAQPRSSDNRQQAPLVSVSPAS--EEVSKGRPTAKFPEQKLFAALLIKCVVQLELIQTIDNIVFFPATSKKEDAENLAAAQRDAVDFD---------VRVDTQDQGMYRFLTSQQLFKLLDCLLESHRFAKAFNSNNEQRTALWKAGFKGKSKPNLLKQETSSLACGLRILFRMYTDESRVSAWEEVQQRLLNVCSEALSYFLTLTS---ESHREAWTNLLLLFLTKVLKISDNRFKAHASFYYPLLCEIMQFDLIPELRAVLRRFFLRIGIVFQISQPPEQELGINKQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6D6-1", "uniprot_id": "BIG1_HUMAN", "id": "Q9Y6D6-1", "name": "Brefeldin A-inhibited guanine nucleotide-exchange protein 1", "aln": "-------------------------MYE-GKKTKNMFLTRALEKILADKEVKKAHHSQLRKACEVALEEIKAETEKQSPPHGEAKAGSSTLPPVKS-KTNFIEADKYFLPFELACQSKCPRIVSTSLDCLQKLIAYGHLTGNAPDSTTPGKKLIDRIIETICGCFQGPQ---TDEGVQLQIIKALLTAVTSQHIEIHEGTVLQAVRTCYNIYLASKNLINQTTAKATLTQMLNVIFAR---MENQAL------------------QEAKQMEKERHRQHHHLLQSPVSHHEPESPQLRYLPPQTVDHISQEHEGDLDLHTNDVDKS--LQDDTEPENGSDISSAENEQTEADQATAAETLSKN---EVLYDGENHDCEEKPQDIVQNIVEEMVNIVVGDMGEGTTINASADGNIGTIED-------------------------------------------GSDSENIQANGIPGTPISVAYTPSLPDDRLSVSSNDTQESGNSSGPSPGAKFSHILQKDAFLVFRSLCKLSMKPLSDGPPDPKSHELRSKILSLQLLLSILQNAGPIFRTN---------EMFINAIKQYLCVALSKNGVSSVPEVFELSLSIFLTLLSNFKTHLKMQIEVFFKEIFLYILETSTSSFDHKWMVIQTLTRICADAQSVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRGSQ---------------------------------------ELGMSNVQELSLRKKGLECLVSILKCMVEWSKDQYVNPNSQTTLGQEKPSEQEMSEIKHPETINRYGSLNSLESTSSSGIG-----SYSTQMSGTDNPEQFEVLKQQKEIIEQGIDLFNKKPKRGIQYLQEQGMLG-TTPEDIAQFLHQEERLDSTQVGEFLGDNDKFNKEVMYAYVDQHDFSGKDFVSALRMFLEGFRLPGEAQKIDRLMEKFAARYLECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSK-DLPEEYLSAIYNEIAGKKISMK-ETKELTIPTKSSKQN--------VASEKQRRLLYNLEMEQMAKTAKALMEAVSHVQAP---FTSATHLEHVRPMFKLAWTPFLAAFSVGLQDCDDTEVASLCLEGIRCAIRIACIFSIQLERDAYVQALARFTLLTVSSGITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKPRYISGTVRGREGSLTGTKDQAPDEFVGLGLVGGNVDWKQIASIQESIGETSS---------QSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELLS---TTHPRMFSLQKIVEISYYNMGRIRLQWSRIWEVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKRNRSPTIRDMVVRCIAQMVNSQAANIRSGWKNIFSVFHLAASDQDESIVELAFQTTGHIVTLVFEKHFPATIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRHCAKYVSDRPQAFKEYT----SDDMNVAPEDRVWVRGWFPILFELS-CIINRCKLDVRTRGLTVMFEIMKTYGHTYEKHWWQDLFR-IVFRIFDNMKLPEQQ------TEKAEWMTTTCNHALYAICDVFTQYLEVLSDVLLDDIFAQLYWCVQQDNEQLARSGTNCLENVVILNGEKFTLEIWDKTCNCTLDIFKTTIPHALLTWRPNSGETAPPPPSPVSEKPLDTISQKSVDIHDSIQPRSVDNRPQAPLVSASAVN--EEVSKIKSTAKFPEQKLFAALLIKCVVQLELIQTIDNIVFFPATSKKEDAENLAAAQRDAVDFD---------VRVDTQDQGMYRFLTSQQLFKLLDCLLESHRFAKAFNSNNEQRTALWKAGFKGKSKPNLLKQETSSLACGLRILFRMYMDESRVSAWEEVQQRLLNVCSEALSYFLTLTS---ESHREAWTNLLLLFLTKVLKISDNRFKAHASFYYPLLCEIMQFDLIPELRAVLRRFFLRIGVVFQISQPPEQELGINKQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q904-1", "uniprot_id": "A0A2R8Q904_DANRE", "id": "A0A2R8Q904-1", "name": "", "aln": "-------------------------MYE-GKKTKNMFLTRALEKILADKEVKKAHHSQLRKACEVALEEIKQESEKLSSPVGDNKSSSSTLPPIKS-KSSFIEADKYFLPFELACQSKCPRIVITSLDCLQKLIAYGHLTGSAPDNTTPGKKLIDRIIETICGCFQGPQ---TDEGVQLQIIKALLTAVTSQQIEIHEGTVLQAVRTCYNIYLASKNLINQTTAKATLTQMLNVIFAR---MENQALTNHKISWSLASRKRDRQLQEAKQMERERHRQH-----SPVSQQEPESPGQRHT-ETPGKTLPAEGNGGPGHQGGKVEQGSPPYESPEPENGSDFCPAENEQTEADQATAAAQSAAEHATEASEEDERQNYEEKAQEIVESVLLEVVNTVATGNMYVTEMKASHEGEAESAEVSPNSLEEEGGL--------------------------------GSDNENVHANGIPGTPISASFTPSLPDDRLSVSSNDTQESVATSGQAPGAKFSHILQKDAFLVFRSLCKLSMKPLSDGPPDPKSHELRSKVLSLQLLLSILQNAGPIFKTN---------EMFINAIKQYLCVALSKNGVSSVPEVFELSLSIFLTLLSNFKTHLKMQIEVFFKEIFLYILETSTSSYDHKWMVIQTLTRICADAQSVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRGGH---------------------------------------ELGTTPLQELTLRKKGLECLVSILKCMVEWSKDQYVNPNSQTSLGQEKPSEQESNESKHPETINRYGSINSLDSTASSGIG-----SYSTQMSGTDNPEQFEVLKQQKEIIEQGIDLFNKKPKRGIQYLQEQGMLG-TTPEDIAQFLHQEERLDSIQVGEFLGDNDRINKEVMYAYVDQMDFQGKDFVPALRMFLEGFRLPGEAQKIDRLMEKFAARYLECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSK-DLPEEYLSAIYDEIAGKKISMK-ETKELTL--KSNKQS--------VASEKQRRLLYNVEMEQMAKTAKALMEAVSHVQAP---FTSATHLEHVRPMFKLAWTPFLAAFSVGLQDCDDTEVASLCLEGIRCAIRIACIFSIQLERDAYVQALARFTLLTASSGITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEIMKCISQLELAQLIGTGVKARYISGTVRGKEGFITSTKEQTSDEYLGL---GGNVDRKQIASIQESIGETSS---------QSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELAS---PTHPRMFSLQKIVEISYYNMGRIRLQWSRIWEVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKKNRSPTIRDMVVRCIAQMVNSQAGNIRSGWKNIFSVFHLAASDQDESIVELAFQTTGHIVTNVFEKHFPATIDSFQDAVKCLSEFACNASFPDTSMEAIRLIRHCAKYVSDRPQAFKDYT----SDDMNVAPEDRVWVRGWFPILFELS-CIINRCKLDVRTRGLTVMFEVMKTYGHTYEKHWWQDLFR-IVFRIFDNMKLPEQQ------TEKAEWMTTTCNHALYAICDVFTQYFESLSDVLLDDILSQLYWCVQQDNEQLARSGTNCLENVVILNGEKFNPETWDKTCNCMLDIFKTTIPHMLLTWRP-AGAEGDHMTQLESDKQLDSISQKSVDIQT----RSDDQQSVNSMEKALADN--RRYSQFSVASEAQEQRLFAALLIKCVVQLELIQTIDNIVFFPATSKKEDAENFAAAQRDALDAD---------IHVDTQDQGMYRYLTSEQLFKLLDCLLESHRFAKAFNSNNEQRTALWKAGFKGKSKPNLLKQETSSLACGLRILFRMYTDPSRRDAWEEVQRRLLNVCSDAVAYFLTLTS---ESHREAWTNLLLLFLTKVLKISDDRFKAHASRYYPLLCEIMQFDLIPELRAVLRKFFLRIGLVFQITNSLETNQTVSNA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJW1-1", "uniprot_id": "Q9VJW1_DROME", "id": "Q9VJW1-1", "name": "", "aln": "-------------------------MHNNSTKTKEMFIVRALEKILADKDIRRSHHSQLKKSCDSALEQIKAELISAGQIAEGNELPCAALPLPKNDAASIINAETYFLPFELACKSRSPRIVVTALDCLQKLIAYGHLTGSIQDSANPGHLLIDRIVVTIYGCFSGPQ---TDEAVQLQIIKALLTVVTSQHVEIHEFTLLQAVRTCYDIYLSSKNLVNQTTARATLTQMLNVIFAR---MENQVY-------------------------------------------ELPPP------------------------------------NSNPTNGS-------IHSEDCNGSGEESLRDS-------------DEVIASELLAEIISAAYNEAMKDQESVGEPEPTLNG----------------------------------------------------------------------------NDYSSHSDHDSVELHSENDAVVTAKFTHILQKDAFLVFRALCKLSMKPLPDGHPDPKSHELRSKVLSLHLLLLILQNAGPVFRSN---------EMFIMAIKQYLCVALSNNGVSLVPEVFELSLSIFVALLSNFKVHLKRQIEVFFKEIFLNILEANSSSFEHKWMVIQALTRICADAQSVVDIYVNYDCDFSAANLFERLVNDLSKIAQGRQAL---------------------------------------ELGANPMQEKSMRIRGLECLVSILKCMVEWSKDLYVNPNMPVPPMQVQSP--TSTEQDQADTT-----IQTMHSGSSHSLN-----SNQEQLQ--DLPEALEERKMRKEVMETGIELFNRKPQKGVQFLQEKQLLG-ATCGDIARWLHEDERLDKTVIGNYIGENDDHSKEVMCAYIDAFDFRQMEVVAALRFLLEGFRLPGEAQKIDRLMEKFASRYCECNPKNQLFQSADTVYVLAFSIIMLTTDLHSPQVKHKMTKEQYIKMNRGISDSKSDLPEEYLSSIYDEISEHEIKMKNNSGMLQQAKPTGKQA--------FITEKRRKLLWNMEMEVISLTATNLMQSVSHVKSP---FTSAKHLEHVRPMFKMAWTPFLAAFSVGLQDCDDPEIATLCLDGIRCAIRIACIFHMSLERDAYVQALARFTLLNANSPINEMKAKNIDTIKTLIMVAHTDGNYLGSSWLDIVKCISQLELAQLIGTGVRPQFLSGAQTTLKDSLN-------------------------PSVKEHIGETSS---------QSVVVAVDRIFTGSMRLDGDAIVDFVKALCQVSVDELQ----QQQPRMFSLQKIVEISYYNMERIRLQWSRIWQVLGEHFNAVGCNSNEEISFFALDSLRQLSMKFMEKGEFSNFRFQKDFLRPFEHIMKKNASPAIRDMVVRCIAQMVNSQAHNIRSGWKNIFSIFHLAAGDNEEPIVELAFQTTGKIIGDLYKRQFAIMVDSFQDAVKCLSEFAT-ARFPDTSMEAIRLVRTCAQCVHEAPQLFAEHAG--MENDASVAEEDRVWVRGWFPMLFSLS-CVVNRCKLDVRTRALTVLFEIVKTYGESFKPHWWKDLFN-VIFRIFDNMKLPEHV------TEKSEWMTTTCNHALYAIIDVFTQYFDVLGHLLLEELFAQLHWCVQQSNEQLARSGTNCLENLVISNGFKFNESTWDKTCQCILDIFNATLPQDLLSWRPKAHSS-------------NNIPQ--------------------------------------------EHNHFEALHIRCVVQLELIQTMDNIVFFPATSRKEDAETLAQAAADLTGGRSG--SQSQLLECQREEQGMYGYLRTRQLLTLADCLMQSHRFAKRFNADHDQRSLLWRAGFKGSVKPNLLKQETSSLACVLRIFFKMYGDENRRSDWPGIEQELVQVCKEALGYYLSLQS---EAHRDAWTSLLLLILTRLLKMSDARFATHVSNYYSLLCEMMCFDLKPELRSVLRRVFMRIGPVFNIMSVK---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P11075-1", "uniprot_id": "SEC7_YEAST", "id": "P11075-1", "name": "ADP-ribosylation factor guanine nucleotide-exchange factor SEC7", "aln": "MSEQNSVVNAEKGDGEISSNVETASSVNPSVKPQNAIKEEAKETNGEDQKCKGPENAGSTAETKETSNDATNGMKTPEETEDTNDKRHDDEGEDGDEDEDEDEDEDEDNGDEDDEDVDSSSSETSSEDGEDSESVSGESTESSSGEDEESDESDGNTSNSSSGDESGSEEEEEEEEEEEEEENAGEPAIAHQDSVPTNDSTAPRSTHTRNISLSSNGSNTNSTIILVKTTLETILNDKDIKKNS----------------------NAQKAIERTLQKFKEFDPQTTNNPHYVDSILVFEALRASCRTKSSKVQSLALDCLSKLFSFRSLDETLLVNPPDSLASNDQRQDAADGITPPPKQKIIDAAIDTISDCFQGEGTDDRVELQIVRALSSCILEEDSSSLCHGASLLKAIRTIYNVFVFSLNPSNQGIAQATLTQIISSVYDKIDLKQSTSSAVSLSTKNHQQQSAIELSEASENAETPAPLTLENMDKLNDDEERLMDAQQPDSIAITNQDLAVKDAFLVFRVMAKICAKPLET-ELDMRSHAVRSKLLSLHIIYSIIKDHIDVFLSHNIFLPGKERVCFIDSIRQYLRLVLSRNAASPLAPVFEVTLEIMWLLIANLRADFVKEIPVFLTEIYFPISELTTSTSQQKRYFLSVIQRICNDPRTLVEFYLNYDCNPGMPNVMEITVDYLTRLALTRVEITQTQRSYYDEQISKSLSTYNFSQLPLLTSSNLSSSPDVGQVNLLFPLDFALKMVSLNCIVSVLRSLSSWAHKALNPNTHTANKVLLNTTSSARQESRSSLSNDVRSSIMTSNDDFKPTYEDEESRSLSSQNIDADDPTQFENLKLRKTALSECIAIFNNKPKKAIPVLIKKGFLKDDSPISIAKWLLETEGLDMAAVGDYLGEGDDKNIAIMHAFVDEFDFTGMSIVDALRSFLQSFRLPGEGQKIDRFMLKFAERFVDQNPG--VFSKADTAYVLSYSLIMLNTDLHSSQIKNKMSLQEFLENNEGIDNGR-DLPRDFLEGLFNEIANNEIKLISEQHQAMLSGDTNLVQQQQSAFNFFNSRDLTREAYNQVSKEISSKTELVFKNLNKNKGGPDVYYAASHVEHVKSIFETLWMSFLAALTPPFKDYDDIDTTNKCLEGLKISIKIASTFRINDARTSFVGALVQFCNLQN---LEEIKVKNVNAMVILLEVALSEGNYLEGSWKDILLVVSQMERLQLISKGIDRDTVPDVAQARVANPRVSYESSRSNNTSFFDVWGKKATPTELAQEKHHNQTLSPEISKFISSSELVVLMDNIFTKSSELSGNAIVDFIKALTAVSLEEIESSENASTPRMFSLQKMVDVCYYNMDRIKLEWTPLWAVMGKAFNKIATNSNLAVVFFAIDSLRQLSMRFLDIEELSGFEFQHDFLKPFEYTVQNSGNTEVQEMIIECFRNFILTKSESIKSGWKPILESLQYTARSSTESIVLKTQLLVSNDIVTNHFENVFSQEDAFSELVGVFREITKNKRFQKLSLHALESLRKMTQNVADICFYNENKTEEERKHNDALLRGKDIFQDVWFPMLFCFNDTIMTAEDLEVRSRALNYMFDALVAYGGKFNDDFWEKICKKLLFPIFGVLSKHWEVNQFNSHDDLSVWLSTTLIQALRNLIALFTHYFESLN-RMLDGFLGLLVSCICQENDTIARIGRSCLQQLILQNVSKFNEYHWNQIGDVFDKLFDLTTANELFDYDPLQQGRKSSVSHHQTTNDTSQHSDDDSNDRRENDSNISETVERAHQEESSEDVGGDMVETLNGQTKLNNGNSVPTVKDELNPKPASLSIPKKTKHMKRNESNEDIRRRINIKNSIVVKCVLQLLMIELLNELFENEDFAHCIPYKEAIRITRLLEKSYEFSRDFNEDYGLRTRLVEARVVDK-IPNLLKQETSAAAVLLDIMFQLYLNDDEKK--ADLITRLITICIQVVEGYVSLDDRTMERSINAWRSVIVEILQGYYEFDDEDFRLYCPAMYALVIQILDKSVPTELRHAIKQFLSRVGELYLSTD-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *.:: : .* *. *:. : ..:: . : :: . . . . . : : * . .. :: * :. . *. * .. .. .. : * .*.: :* : : :* ..:: *. : : :* *:*:. .::* . * : .:: : :. . . . * . : : :. * : .:: . .: :: . ...: . . .: ******** :.*:. *** * :** :***:***::: *::: :* :: ** :*:*** :.**.*..* :. ***::*.*: *::*::..: :* **:.**:: * * .:*: ::* .:..: *** *.:::*::*:****: . .*::* *: *:::* * ::. : ::: .*:*:**:*:.: .*::. . . :.. * . : : : .. . * . * * * :* * :* :. * :**.**::.: * :: :* : .**::* : * ** *:::*:.* . :* *::* ** ..* *** :*:.******.*****:* *** *: : * :* .***.***::*:***.*****.*:*:**: ::::: *.**.:.: ***.::*..:::**: ::*.: : : . :.. : :* : :: .: ::: :.: :. : :*.*:***:.:*: * .****:: ::* ** : :. **:*:: :*:**. * :. * ::* **.:* * : *:* **:::: *: ** ::**** .** :*: :**:* ***..*: :... : :: .:* * ..:** :*.*** * .*.*:*****:: * **::*: ********:*::.**** **:*:*: :* *:*. ** :. *.* : :**:********:*:: *::.*.**:***:***: ::.. .. :::*::.*: ::: ::: .*:**** *:. :: :* .. *.** : .: : . .:. *:*.: * : *:: * . *:.*:. :* :: * : : : ..: : . :: ***:** :. ::. .*:**:*.*. :*: : :** .:: .:*:.: . ::* **. :. . : : *::** :** : :**:*:: *. :*: ::. * *: *.*: :** * .**::::: * **. *:: : .:*. * .: *: : * . .: : . . :: . : :. .: .: .. :** . . :. :::.: : .: : : * :*:.*:: ** : *: * .* . .. *********: * * *:*::* : .. . : .*: :* :.: :::* . * :** .::: :* ::.* * : . *.*: ::: .: .*** .:::.: *:* :: . ", "identical_positions": 391, "similar_positions": 599, "identity": "19.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1091", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P25093-1", "uniprot_id": "FAAA_RAT", "id": "P25093-1", "name": "Fumarylacetoacetase", "aln": "--MSFIPVAEDSDFPIQNLPYGVFSTQSN-PKPRIGVAIGDQILDLSVIKHLFTGPVLSKHQHVFDETTLNSFMGLGQAAWKEARASLQNLLSASQAQLRDDKELRQRAFTSQASATMHLPATIGDYTDFYSSLQHATNVGIMFRGKENALLPNWLHLPVGYHGRASSVVVSGTPIRRPMGQMRPDNSKPPVYGASKRLDMELEMAFFVG-PGNRFGEPIPISKAQEHIFGMVLMNDWSARDIQQWEYVPLGPFLGKSFGTTISPWVVPMDALMPFVVPNPKQDPKPLPYLCHSQPYTFDINLSVALKGEGMSQAATICRSNFKHMYWTILQQLTHHSVNGCNLRPGDLLASGTISGSDPESFGSMLELSWKGTKAIDVGQGQTRTFLLDGDEVIITGHCQGDGYRVGFGQCAGKVLPALSPA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35505-1", "uniprot_id": "FAAA_MOUSE", "id": "P35505-1", "name": "Fumarylacetoacetase", "aln": "--MSFIPVAEDSDFPIQNLPYGVFSTQSN-PKPRIGVAIGDQILDLSVIKHLFTGPALSKHQHVFDETTLNNFMGLGQAAWKEARASLQNLLSASQARLRDDKELRQRAFTSQASATMHLPATIGDYTDFYSSRQHATNVGIMFRGKENALLPNWLHLPVGYHGRASSIVVSGTPIRRPMGQMRPDNSKPPVYGACRLLDMELEMAFFVG-PGNRFGEPIPISKAHEHIFGMVLMNDWSARDIQQWEYVPLGPFLGKSFGTTISPWVVPMDALMPFVVPNPKQDPKPLPYLCHSQPYTFDINLSVSLKGEGMSQAATICRSNFKHMYWTMLQQLTHHSVNGCNLRPGDLLASGTISGSDPESFGSMLELSWKGTKAIDVEQGQTRTFLLDGDEVIITGHCQGDGYRVGFGQCAGKVLPALSPA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16930-1", "uniprot_id": "FAAA_HUMAN", "id": "P16930-1", "name": "Fumarylacetoacetase", "aln": "--MSFIPVAEDSDFPIHNLPYGVFSTRGD-PRPRIGVAIGDQILDLSIIKHLFTGPVLSKHQDVFNQPTLNSFMGLGQAAWKEARVFLQNLLSVSQARLRDDTELRKCAFISQASATMHLPATIGDYTDFYSSRQHATNVGIMFRDKENALMPNWLHLPVGYHGRASSVVVSGTPIRRPMGQMKPDDSKPPVYGACKLLDMELEMAFFVG-PGNRLGEPIPISKAHEHIFGMVLMNDWSARDIQKWEYVPLGPFLGKSFGTTVSPWVVPMDALMPFAVPNPKQDPRPLPYLCHDEPYTFDINLSVNLKGEGMSQAATICKSNFKYMYWTMLQQLTHHSVNGCNLRPGDLLASGTISGPEPENFGSMLELSWKGTKPIDLGNGQTRKFLLDGDEVIITGYCQGDGYRIGFGQCAGKVLPALLPS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58FY41-1", "uniprot_id": "A0AC58FY41_DANRE", "id": "A0AC58FY41-1", "name": "Fumarylacetoacetase", "aln": "--MSFIKTEEKSDFSYHNLPYGVFSTPDNQARHRIGVAIGDQILDLSVIKHLFKGPALQPHQHVFEQPTLNAFMALGYEAWREVRKTLQMLLSANEPTLRDDVSLRSRAFVHQSLAVMHLPAEIGDYTDFYSSRDHATNVGIMFRGKENALMPNWLRLPVGYHGRASSVLVSGTAIRRPKGQMRPDAAQPPIFGPSKQLDIELEMAFFVG-KGNKLGEPIPIEKAHEHIFGMVIMNDWSARDIQAWEYVPLGPFLGKNFGTTISPWVVPMEALMPFVEPNPVQDPVPLPYLRHDDPYTFNINLFVSVKGEGMREATTICKSNFKHMYWSMKQQLAHHTVNGCNVRPGDLLASGTISGPDPESFGSMLELSWRGTKTIDLGGGETRTFLKDGDEVTLSGYCEGQGFRVGFGLCEGKILPALQQ--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZI8-1", "uniprot_id": "Q9VZI8_DROME", "id": "Q9VZI8-1", "name": "Fumarylacetoacetase", "aln": "MSQSFVPVPENSDFPLENLPYAVFSTENN-KVHRICVAIGEHVLDLKAVSQLFP----FQVQKSLQAETLNELMGLDFEAWDVVRSQTQKLLTK-GSELDHNVDLKAVSIVPQSEIKLHLPAQIGDYTDFYSSIHHATNVGIMFRGPDNALMPNWRHLPVGYHGRASSVVVSGTPIRRPLGQTFPDGAEKPVFGACKLLDFELEMAFFIGGKGNQLGEPIRVDEAWKNVFGFTLMNDWSARDIQKWEYVPLGPFTAKNLGTTISPWVVPTAALKPFVLDNFPQEPEVLPYLRQNIPFNFDINLEVSLKPADQNE-ALISKSNFKHLYWTPLQQIAHHTVTGCNLRPGDLMASGTISGETPDSYGSLLELCWKGTKTLELPGGKTRKFLQDFDEVIIRGHCEKNGLRIGFGECVGQVLPAHPVPQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: . *.***. .****.**** .: ** ****:::***. :.:** *. :: *** :*.*. ** .* * **: . * .: .*: :: *: :**** ********** .**********. :***:*** :***********::****.**** ** ** :: *::*..: **:*******:* **::**** :.:* :::**:.:********** ********* .*.:***:****** ** **. * *:* **** :. *:.*:*** * :* . : : *.:****::**: **::**:*.***:*****:******* *:.:**:***.*:***.::: *:**.** * *** : *:*: :* *:*** * *::*** ", "identical_positions": 219, "similar_positions": 105, "identity": "51.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1107", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZK25-1", "uniprot_id": "D3ZK25_RAT", "id": "D3ZK25-1", "name": "", "aln": "MEERKEEGEAEIQEHGPEHWFSKWERQCLAEAEQDEQLSPELQEEAAAAAQPEH-KQQKLWHLFQNSATAVAQLYKDRVCQQP---GLSLWVPFQNAATAVTNLYKESVDTHQRSFDIGIQIGYQRRNKDVLAWVK-KRRRTIRREDLISFLCG-KVP----PPRNSRAPPRLTVVSPNRATSTET---SSSVETDLQPFREAIALHGLSGAMASISVR--SSTPGSPTHVSSGPNASRRRNGLHDVDLNTFITEEMALHLDNGGTRKRTSAQCGDVITDSPTHKRNRML", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14AM7-1", "uniprot_id": "HAPR1_MOUSE", "id": "Q14AM7-1", "name": "HUWE1-associated protein modifying stress responses", "aln": "MEERKEEGEAEIQEHGPEHWFSKWERQCLAEAEQDEQLSPELQEEAAAAAQPEH-KQQKLWHLFQNSATAVAQLYKDRVCQQP---GLSLWVPFQNAATAVTNLYKESVDTHQRSFDIGIQIGYQRRNKDVLAWVK-KRRRTIRREDLISFLCG-KVP----PPRNSRAPPRLTVVSPNRATSTET---SSSVETDLQPFREAIALHGLSGAMASISVR--SSTPGSPTHVSSGPNASRRRNGLHDVDLNTFITEEMALHLDNGGTRKRTSAQCGDVITDSPTHKRNRML", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14CZ0-1", "uniprot_id": "HAPR1_HUMAN", "id": "Q14CZ0-1", "name": "HUWE1-associated protein modifying stress responses 1", "aln": "MEERKEEGEAEIQEHGPEHWFSKWERQCLAEAEQDEQLPPELQEEAAAAAQPEH-KQQKLWHLFQNSATAVAQLYKDRVCQQP---GLSLWVPFQNAATAVTNLYKESVDTHQRSFDIGIQIGYQRRNKDVLAWVK-KRRRTIRREDLISFLCG-KVP----PPRNSRAPPRLTVVSPNRATSTET---SSSVETDLQPFREAIALHGLSGAMASISVR--SSTPGSPTHVSSGSNASRRRNGLHDVDLNTFISEEMALHLDNGGTRKRTSAQCGDVITDSPTHKRNRMI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BE76-1", "uniprot_id": "HAPR1_DANRE", "id": "A2BE76-1", "name": "HUWE1-associated protein modifying stress responses", "aln": "MEEKKEEGEAEIQEHGPEHWFSKWERQCLAEAEQEE----------PAEEETDQ-SQQKLWHLFQNSATAVAQLYKDRVCQQQQ--GLSLWVPFQNAATAVTNLYKESVDAHQRSYELGIQIGHQRRNKDVLAWVK-KRRRTIRREDLISFLCG-KAP----PPRSSRAPPRLAMVSPSRSTPSET---SSSVETDLQPFREAIALHGLSGAMASISMR--SGAPGSPTHLSASSAPSRRRNGLHDVDLNTFIAEEMALHLDNG-TRKRSSAQCNDVITDSPTHKRNRMI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1LW04-1", "uniprot_id": "F1LW04_RAT", "id": "F1LW04-1", "name": "", "aln": "MEEQQKDREAEVAGP----WFSKWERQCLAEAEQ---LSPELQEEAAADAAGLKIERQRLWHLFQISATAVAQLYKDSGCQQP---GLSMWDPFQNAAMAVTSLYKESGDASQRSFELGVQVGYQRRVRDVLEWVK-KGRSIIRREDLISFLCG-KVPPTPPPLRTSWTSPRPPAAASTQAAATES---SAPVDVDLQPFHEAIALHGLSGAMASISMR--SGTP-SSSQDGGIASSGRRKSSFLEDDQNPLSSEELALRLDSGGIRKRTSAQLGDGATDSPSHKRNRMV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A804C8T0-1", "uniprot_id": "HAPR2_MOUSE", "id": "A0A804C8T0-1", "name": "HUWE1-associated protein modifying stress responses 2", "aln": "MEDQPKDREAEVAGP----WFSKWERQCLAEAEQAEQLSPELQEEAAADAAGLKIERQRLWHLFQISATAVAQLYKDSGCQQP---GLSMWDPFQNAAMAVTSLYKESGDAYQRSFELGVQVGYQRRVRDVLEWVK-KGRSIIRREDLISFLCG-KVPPTPQPPRTPRMSPRPPAAASTQAAATES---GTPVGVDLQPFHEAIALHGLSGAMASISMR--SGPPGSSSQDGGIASSGRWKSSFLENDPNSLSSEELTLLLDSGGVRKRTSAQFGDGSADSPLHKRNRMV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A7P0TBJ1-1", "uniprot_id": "HAPR2_HUMAN", "id": "A0A7P0TBJ1-1", "name": "HUWE1-associated protein modifying stress responses 2", "aln": "MEEQQKEGEAEVAEH----WFSKWERQCLAEAEQEEQLPPELQEEAAAELAGLKSEKQKLWHLFQISATAVAQLYKDSGCQQQ---GLSMWDPFQNAAMAVTSLYKESGDAHQRSFDLGVQVGHQRRIKDVLEWVK-KGRSTIRREDLISFLCG-KVPPAPPPPRTPRTPPKPPTGVTSQAVATES---SSSVDVDLQPFQEAIALHGLSGAMAGISMR--SGDS---PQDSGVASSGRRKTSFLEDDLNPFDSEELALHLDSGGIRKRTSAQCSDGITDSPIQKRNRMV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXB1-1", "uniprot_id": "Q9VXB1_DROME", "id": "Q9VXB1-1", "name": "", "aln": "MQQQPESGGEE----------SWLEEQCHREIHG------QHDEYEREFVRQRDNNLGTVWGAFQDSATAVAQLYRERSSNTFSSDTGALWLPFQTAAGTVTTLYKESCDGLKRTSDAAIQCGYQRRTRELADWARSKKRRMIRREDLLAYLAGKPLPPCNSNPHANRRSPKPEHHHQSGSGGSGLGFHGSGLGLTGGPLTAAGGGHLLSAGAAGGRQEGTGGAPGGGIGDDLHTFKEALVLRPRGPELLAFVANEIARHCKRPGSPIDDKMDICHYSS-----KRQRFM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::: :. * * *.** * . . . :* ** *********:: .: ::* ***.** :**.***** * :*: : .:* *:*** ::: *.: * * ******:::*.* * : .*: . : : .: : *: * . * **.. *. . .. . . . : .: ::*:: . . : . : **:*::", "identical_positions": 62, "similar_positions": 69, "identity": "21.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1132", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15088-1", "uniprot_id": "CBPA3_HUMAN", "id": "P15088-1", "name": "Mast cell carboxypeptidase A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MRLILPVGLIATTLA---IAPVRFDRE-------------------------KVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHVAANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDV------------------KEDIPGRHSYAKYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGE-KN----ERRKAIFTDCGIHAREWVSPAFCQWFVYQATKTY-----------GRNKIMTKLLDRMNFYILPVFNVDGYIWSWT--KNRMWRKNRSKNQNSK--CIGTDLNRNFNASW-NSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLN--EIKVYITFHSYSQMLLFPYGYTSKLPP-NHEDLAKVAKIGTDVLSTRYETRYIYG----PIESTIYPISGS-SLDWA-YDLGIKHTFAFELRDKGKFG----FLLPESRIKPTCRETMLAVKFIAKYILKHTS--------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P21961-1", "uniprot_id": "CBPA3_RAT", "id": "P21961-1", "name": "Mast cell carboxypeptidase A", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------LMGVIYSTLA---IAPVQFDRE-------------------------KVFRVKLQDEKQASILKNLTQTIELDFWYPDAIHDIAVNMTVDFRVTEKESQTIQSTLEQHKMDYEILINDLQEEIDKQFDV------------------KEEIAGRHSYAKYNDWNKIVSWTEKMVEKHPEMVSRIKIGSTVEDNPLYVLKIGR-KD----GERKAIFMDCGIHAREWVSPAFCQWFVYQAAKSY-----------GKNKIMTKLLDRMNFYVLPVFNVDGYIWSWT--KDRMWRKNRSKNPNST--CIGTDLNRNFDVSW-DSSPNTDNPCLSVYRGPAPESEKETKAVTNFIRSHLN--SIKAYITFHSYSQMLLFPYGYTIKLPP-NHQDLLKVARIATDVLSSRYETRYIYG----PIASTIYKTSGS-SLDWA-YDLGIKHTFAFELRDKGKSG----FLLPESRIKPTCKETMLSVKFIAKYILKHTS--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15086-1", "uniprot_id": "CBPB1_HUMAN", "id": "P15086-1", "name": "Carboxypeptidase B", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MLALLVLVTVALASAHHGGEHFEGE-------------------------KVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDS------------------RVRATG-HSYEKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGK-AG----QNKPAIFMDCGFHAREWISPAFCQWFVREAVRTY-----------GREIQVTELLDKLDFYVLPVLNIDGYIYTWT--KSRFWRKTRSTHTGSS--CIGTDPNRNFDAGW-CEIGASRNPCDETYCGPAAESEKETKALADFIRNKLS--SIKAYLTIHSYSQMMIYPYSYAYKLGE-NNAELNALAKATVKELASLHGTKYTYG----PGATTIYPAAGG-SDDWA-YDQGIRYSFTFELRDTGRYG----FLLPESQIRATCEETFLAIKYVASYVLEHLY--------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19223-1", "uniprot_id": "CBPB1_RAT", "id": "P19223-1", "name": "Carboxypeptidase B", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MLLLLALVSVALA--HASEEHFDGN-------------------------RVYRVSVHGEDHVNLIQELANTKEIDFWKPDSATQVKPLTTVDFHVKAEDVADVENFLEENEVHYEVLISNVRNALESQFDS------------------HTRASG-HSYTKYNKWETIEAWIQQVATDNPDLVTQSVIGTTFEGRNMYVLKIGK-TR----PNKPAIFIDCGFHAREWISPAFCQWFVREAVRTY-----------NQEIHMKQLLDELDFYVLPVVNIDGYVYTWT--KDRMWRKTRSTMAGSS--CLGVRPNRNFNAGW-CEVGASRSPCSETYCGPAPESEKETKALADFIRNNLS--TIKAYLTIHSYSQMMLYPYSYDYKLPE-NYEELNALVKGAAKELATLHGTKYTYG----PGATTIYPAAGG-SDDWS-YDQGIKYSFTFELRDTGFFG----FLLPESQIRQTCEETMLAVKYIANYVREHLY--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1QJN9-1", "uniprot_id": "F1QJN9_DANRE", "id": "F1QJN9-1", "name": "Carboxypeptidase B", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLFLLLGLVAVALC----EPITFVGD-------------------------KVLQLKPINDEHVTIIRELGEKIKLDFWKPRSADLVSIDMTVDIHVPAAQLAMVSTILQQSDMEVKVMIDNLQEAVKGQMDN------------------RSPTKG-HDYTKYNSWATINDWAISISSANPDLISRQSIGNTYEGRTMHLLKIGKNTG----SNKPAVFMDCGFHAREWITHAFCQWFVNEAVSTY-----------GSDPDMTNLLDRMDFFVLPVFNIDGYEYTWN--RDRMWRKTRSKNSGSS--CIGTDPNRNFNAGW-CTVGASSNPCSDTYCGSSPESEIESKNLANFIRTNKS--VIKAYLTVHSYSQLLLFPYSYKYDLAA-HHSELMSVSQGAIAALRSLYGTKYTSG----PGAATIYPAAGG-SDDWA-YDLGVKYSYTFELRDEGRYG----FLLPESQIKPTCEETMLAVKYIANHVLNNLY--------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W478-1", "uniprot_id": "Q9W478_DROME", "id": "Q9W478-1", "name": "Peptidase M14 domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------MTQKTMLLQLLLLVAAVAASLANELPSNLTLLDANEIPQ------------RYDEAQLWRIYNISEAMQKRVPVGQMLEQKFGGNIWKEN-------SKFLDISIARDQLKAARSFLSAHRLDPQILSHNIQSMIDEELLEGIQSSS-----FGHGRRTKKAARSSMHWKDYHDLETIYSFMREIRTKFPNIVRLYTIGQTAEGRDLKVLRISE-NP----RENKKVWIDGGIHAREWISPATVTFILYQLMSDW-----------ENQP---AHIRGLTWYIMPVMNPDGYEYSRT--TNRLWRKNRSPSRRAQ--CSGVDLNRNFDIGW-NGYGSSTNPCSDTYRGSAPASERETRAVAEFLAKRKY--NLESYLTFHSYGQMIVYPWAYKAVKVK-DASVLQRVSSLAAERILQKTGTSYRAA----VTHEVLGIAGGG-SDDWSRAALGVKYVYTIELRDRGAYG----FVLPPRFIKDTALEGWTVVETVAQAIGPSSSG-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VL86-1", "uniprot_id": "CBPA1_DROME", "id": "Q9VL86-1", "name": "Zinc carboxypeptidase A 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MSLNKCLLFALLAIVASASVS-AE-----------------------RVRYDNYRMYKVNSEN---AKQLEVLKDLEGSSDSIMFLDGVHLVGADIQIIVAPHKVPDFLEILGKSEIKYELQSRDVQKSLDEIDEKVAI----------KGRATTAYN-----WAQYYELDDTYAWLQSLAQTNPGVVTLIEGGKTYQGRSILGVKITKGGETINGKAKPGIFLEAGIHAREWIAPAAATFIINQLLT-------------SEVENIKELAENYTWYVLPHANPDGYVYTHT--TNRLWRKTR---TPYG-SCFGADPNRNWGFHW-NEVGASSSACSDTYAGPSAFSEIETLSLSKFIEG--LKGKVQLYLSLHAYSQYLLYPYGHTSDLPD-NVADFEKVFDASIAAVNKRYGTTYTGG----NIYDAIYPAAGA-SVDWAYGTQDVRMAFCYELRPSSTSYLT-GFKLPAEQIVPASEELLDSIVAMATEVKSLGYFD------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VL87-1", "uniprot_id": "Q9VL87_DROME", "id": "Q9VL87-1", "name": "Peptidase M14 domain-containing protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLLLLLLSVNILIFCL-AE-----------------------RQRFDNYKVYRVSPVK---ANQLEGLRSLEANSEDALVLNNLHLG--PTDFLVAPDFDGTFLKLVKDLDLSPELIDANAQTSLSLDIEPIAD----------ANRRSDDYS-----WSEYHELNDTHRWMQNLVGKYPDVVSVFVAGQSYEGRELLGLRINHND---GRAEKQSIFLEAGMHAREWIGPATATYFANELLS-------------SQQQEIMNLARSYVWYILPHANPDGYVYTHK--TNRMWRKTR---SPQDKNCVGTDPNRNWDFHW-REVGASSDPCSESYAGPKAFSEPEVQTLSQFLKS--VPEPMFMFLSLHSFSQLLLYPYGHTSALPE-NHRQLEQIFNTAVGAMKRRYGTRYTGG----NVYDAIYPAAGS-SMDWAYGVLNVKYSFTYELRPSGYSFWT-GFRLPAAQIIPTGQETTDSLVEMIKAAAQIEGYKIE----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E9F9-1", "uniprot_id": "Q0E9F9_DROME", "id": "Q0E9F9-1", "name": "Zinc carboxypeptidase A 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MGN------------KIINMPAARIGTQWLVILCVAMAASG-TN-LDSGICPVAGDSGCRGNPPD-----QARYDNYRIYNVEFEN---QEQIELFQKLEEQSDSLTFIGHAREVGQKLSILVAAHRVADIADLLKTYKVKHRVLTYNFQEKIDRNLAEVQP----------ESIDASQLD-----WQHFFHLKTIYEWLDKMVEKYPNRVTVLDMGSSTQGNAIKGVKLTS-N-----ANNKAIFIESGIHAREWISPAAATYIINQLLT-------------SQDPKVQQLAQDYNWIIFPCVNPDGYKYTFE--HDRMWRKNR---QLFG-TCRGVDLNRNYPDHW-NSTGSSSDPTRYDFAGPSAGSELETKRLIDFIRANAGKEQIKTYIALHSYSQMLMFPYGYTKERVS-NYDDLQEFGKKASAAIKAENGRDYVSG----SLFETIYPSSGG-SMDWAHSEAGIPIAYTFELR-GPPDSQD-LFILPAVEIQPTASEAFTAIRAIVEAAAEKGYYK------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCM8-1", "uniprot_id": "Q9VCM8_DROME", "id": "Q9VCM8-1", "name": "Zinc carboxypeptidase A 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------MYACQSALQENEMEIFYTDFKLRRIKMLPKGGTPKTWLLLLLVSSVCVIQES-KASSFCTKADQCALDEEIKTAADSVQARYDHTRIYQVELAS---EEHVRLFQALEQASDSCSFMGHARQPGQKLTIMVTGAKVADFDDLVHSYNVTHRVLNYNFQALIDANYLEVAP----------EDTKPEEFD-----WKRYHPLESINAWLKKLAETHP-EVLLVELGVSAQGRPILGVQIAFDN-----ENRTTVFVESGIHAREWIAPATATYIIDQLVN-------------SKDSAVQALARSQRWYIFPTVNPDGYQYTFK--GDRMWRKNR---ALFG-ICRGVDLNRNFPFHW-NVTGASGDPCRYDYSGPSAASEVETQRMIEFIRHRVESERIRTFISLHSYSQMIMFPYGHSAERVD-NYHDLTDIGKLAANKIKDVSGRIYKSG----SIYETIYPSSGG-SKDWAHGQLKIPITFSYELR-GPADSED-LFILSAKEIEPTAAEAFASIQTIVQEAGKRGYYQ------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VS66-1", "uniprot_id": "Q9VS66_DROME", "id": "Q9VS66-1", "name": "Peptidase M14 domain-containing protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MKFSLGLLVLFLGATLVA------------------------AEQDYEGYRIYEVIPST---ADQADLLHQLSLQG--YDFISETRLLGHPSRVIVSPAQLKHFQQLVEAEKMTLTLVNSNLGASIAEEFAQRQM----------QRLLAPITGKGRLSTERYYTHEEIINYIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNGD---GKANKKVIFMDGGFHAREWISPAAVLYVIDQLVE-------------QFE-ENAHLLKDYDWVILPLVNADGYEHTQTGTLARMWRKTRQPYTYAGQTCYGADPNRNFDFHW-NEEGASSNPCADTYAGPTAFSEPETITVRDLMHSLAD--RGIMYLTLHSYGNYLLYPWGWTSDLPE-NWEDLDAVARTGAEAIENATGTVYTYG----SSTNVLYIAAGA-SDDYGYYAG-FNVSITMELPGAGSIG----FNPPVTRIDEFVTETWIGIRAMAEKVIEMY---------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VS67-1", "uniprot_id": "Q9VS67_DROME", "id": "Q9VS67-1", "name": "Peptidase M14 domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MTVVWVILALSCLSLSAGLQR------------------------TNK-YEGYKIYEVSSEARS-VAFSEALSELVKNASYYEVFSELN-AGNPGKIMVHPHEQVNFVQLMEENNVKYDIINRNVGLTLSRQFETNRM----------LRHWFPYNG--RLGTERYYNHEEINQFIEDLAGEHPRRVFLKTVGRSYEGRWLKTITITNGD---ARRNKNVILVDGGFHAREWISPAAATYLINQLVY-------------NLE-DNADLLLDFDWVILPVVNPDGYEYTQLSEDTRMWRKTRKPSSSD---CIGTDPNRNFDFHW-NEEGASDDPCDNIYAGAKPFSEPEALVVGDLIHSYVD--RGQMYLTLHSYGSLILYPWGWTAAVPD-TEEDLHEVAAAGQSAIQEATGTIYKIGP---SATTINYAASGA-SDDYAFNAG-FPISFTMELP-FGGTG----FDPPASDIDSIVKETWVGIAAMARKVIQKYPLA------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VS65-1", "uniprot_id": "Q9VS65_DROME", "id": "Q9VS65-1", "name": "Peptidase M14 domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRNYHLEYKVLIEDLAPLVHAQRAENLR----------KKLLIQWPHIDVLSA--FYTHSEINDYLDSLLERFPKRVQVKQFGWSYERRPLKVLTITNGD---GRRNKPVILIDGTVHAREWISPSMALYIIQQLLD-------------NYG-DNQELLQDYDWVIMPVVNADGYEYTHT--DSRYWRKSRRPTSNP--ECIGTDINRNFGYEWGHDEGSSSDPCENIYRGERPFDQSESQVLRDVMLHYKG--RLNFYLSLHSYGNYFLLPWGYTSDFPD-TYQDMMSVADAGAKAIIYSTNGIYSYG----STYYVLYPTSGD-TTDFAFGVVNATVAMTMELPAAGFQG----FDPWISQIERLVTESWVGVRAMAAEVIRRYPS-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VS80-1", "uniprot_id": "Q9VS80_DROME", "id": "Q9VS80-1", "name": "Peptidase M14 domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWKILCGIVVLVTIVVNQLSEAREVRRR----------RGLMLQLDN--------YLSYDGIMQYLDELALSHSNRVTLKDVARTYENRALKMAIITNGD---GRPGKRVIFLDAALHSREWMTPAAALLTIHKLVV-------------EFA-ENSDLLTDYDWHIMPLANPDGYEYSRN--TERYWRNTRTPNGGN---CFGTNLNRNFAVDWNVGFPELKDPCDENYAGSSPFSEVEARTVRDIMHGLVESKRAVMYLSLHTANRSVFYPWVYDTDPVS-NQKEHDEIGRFVADRILQSTGTFIKTWQ---YAKYAG-TFGGT-SMDYALLAG-FPLSFVFEMSGTGRDHVEYKFFPPARDIRHLAEESWTGIKAFAEKTIEKYPPSRVISYNPMVKLAENAATRNLGFNSMVATVCLFFTYLTNCNFF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W477-1", "uniprot_id": "Q9W477_DROME", "id": "Q9W477-1", "name": "Peptidase M14 domain-containing protein", "aln": "MHRLPWKWAWLPLLLLITAKLEQVGGKTYLDWARTDSQLTRLPFFGGGVGHLLRYLHPLSMSPPSERGKISELRSELDANYVSYRGAQLWKLNFNATRGSSMAEREEDDEAAEKRQVLASPDAQFNEVVALFALTFVALIGSVFGQKLLLWRSVSVPEISGISGLPLALLTLNSSELYESTLEGLQWLSPMDLRRFDFISPGSSYQINRRYRNGSQVQRYYGFQLWKVHETRLEQPELRAFWRHFGSEVWNINQDGIDILIEQRNVADARKFMDKVGYSYNIMIDDIESAIDESYVEVPAVEHPLDSVRNNSLPWMEVPGSTMNWRRYHDQADIKQFLQTLLETYSENVELIQIGVTRNKRPLEVIRVSNGNP-----DNWAVFVDAGLQARDWLSPAALTYAISKLTHLWGRPKGKDKGEGQRQSRAEKAMRRIDWYFLPLANPDGYQYSRQ--TDRLWTKNRGYDSVSG--CYGVNLDRNFDYGW-DGTGSTSNPCKNLYRGAHSFSEPESRAVCSFLSGMREY--LGAYVSLGGYGQAITYPWGDADYVTE-NQRNLKQTARRAVLALRRLNQAEYSSG----TSYRQKLARPGN-SADWVQDRIGPQLVFNMFLKDQGRYG----YLLPPHYIVESGEEVFEFLRIIAQQLQ------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38836-1", "uniprot_id": "ECM14_YEAST", "id": "P38836-1", "name": "Inactive metallocarboxypeptidase ECM14", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MLHMNSLWGCFLFVLLAVTGAVQGLQEDYSEYA------------------------VYRFTSDNYSTLVRDVIAPLTDDYDVWTRSNNFIDIKLPKEIGEQINDGQVIIDNMNELIQNTLPTSQMMAREQAVFENDYDFFFN--------------------------EYRDLDTIYMWLDLLERSFPSLVAVEHLGRTFEGRELKALHISGNKPE-SNPEKKTIVITGGIHAREWISVSTVCWALYQLLNRY-----------GSSKKETKYLDDLDFLVIPVFNPDGYAYTWS--HDRLWRKNRQRTHVPQ--CLGIDIDHSFGFQW---EKAHTHACSEEYSGETPFEAWEASAWYKYINETKGDYKIYGYIDMHSYSQEILYPYAYSCDALPRDLENLLELSYGLSKAIRSKSGRNYDVISACKDRGSDIFPGLGAGSALDFMYHHRAHWAFQLKLRDTGNHG----FLLPPENIKPVGKETYAALKYFCDFLLDPEI--------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : : . : . : : . : : . : .::*:*: : : : .:* * *** : * * :.* * * ::.: * . : * . . * . : :: . . . *: : * : : : * * : . ", "identical_positions": 19, "similar_positions": 50, "identity": "2.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1135", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35403-1", "uniprot_id": "ST3A1_MOUSE", "id": "O35403-1", "name": "Amine sulfotransferase", "aln": "------------MDNKDEYLLN-FKGYNFQKTLVKMEV------------------VENIENYEIRDDDIFIVTYPKSGTIWTQQILSLIYFEGHRNRTENIETIDRAPFFEYN--------IHKLD-----------YAKMPSP-------------RIFSSHIPYYLVPKGLKDKKAKILYMYRNPKDVLISYFHFSNLMLIFQNPDTVESFMQTFLDGDVVGSLWFDHIRGWYEHRHDFNIMFMSFEDMKKDFRSSVLKICSFLEKELSEEDVDAVVRQATFQKMKADPRANYEHIIK---DELGTRNEMGSFLRKGVVGAWKHYLTVDQSERFDKIFHRNMKNIPLKFIWDINEE-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G5E904-1", "uniprot_id": "G5E904_MOUSE", "id": "G5E904-1", "name": "Sulfotransferase", "aln": "------------MDNKDEDIFK-FKGYNFLRALVSMDI------------------VKNMEDYEIRDDDIFIVTYPKSGTTWTQQILCLICFESHRNGTENIATIDRIPSFEYN--------IHKLD-----------YAKMPSP-------------RIFTSHIPYYLVPKGLKDKKAKIIYVYRNPKDVLISFFHFSNLMVVLKASDTLENFMQRFLNGNLVGSLWFDHIRGWYEHRHDFNIMFMSFEDMKKDLRSSVLKICSFLEKELSEEDMDAVVRQATFEKMKADPRANNEHIIK---DELGTRNNTGAFLRKGIVGDWKHYLTVDQSERFDKIFHMNMKNIPLKFIWNINEK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q1L875-1", "uniprot_id": "Q1L875_DANRE", "id": "Q1L875-1", "name": "Sulfotransferase", "aln": "------------MAQEECKMIS-DKLLKYKGTVLTMETN----------HDITPEYIDSLQDFETRDDDVFVVTFPKSGTVWTQRIMTLIYEEDFP-EKANEITYEQMPWIEYR--------EKGKD-----------YNARPSP-------------RLFCSHLLEPLMPRALQ-KKGKVIYVMRNPKDVMVSYFHFSNKMKNLDSSENYDEILENFFTGCMIGGSWFDHVKGWVTSKDKYNILILTYEEMIKDLRSVIVKICKFVGKNLSDAAINKVVERTTFNQMKVDPVANYESLPQ---EVTDQP--KGVFMRKGTVGDWKNSLTVAQSECVDRVFEERMKHVPLNLVWDIAELRG---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1L8-1", "uniprot_id": "Q9W1L8_DROME", "id": "Q9W1L8-1", "name": "", "aln": "MPQSSFFAKSVPFEQIDKLAISGGYSSIFASSKPSVPVVGNWEQRFCRLADTFQPVLDRVYDFEVRDDDVWIVTLPKCGTTWMQELAWLVINECDFETAKSVDLTHRSPFLEFNGVVPNVPHDTIAA-----------ANALPSP-------------RLIKSHLPAWMLPRQIWSKRPKIIYVYRNPKDAAISYFHHWRGMVGYQG--TKSDFMHSFIDGYVNFTPCWPHILDFWQLRHEPNIFFTSYERMKGQLGQVISEVAQFLERSVSQEQMQQMQRHLSFESMRDNPACNHVKEFESMKAAAGREVEEFRFVRRGVVGSHKDELTADIIREFDLWSDSNLRDFKLNMDDFANYSKFAST", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z9J8-1", "uniprot_id": "A1Z9J8_DROME", "id": "A1Z9J8-1", "name": "", "aln": "-MENTPLKFPHEIRDVEESTNAELLDHFHGERTGFVQVGSEG----YFFPHKYKDEAERYYNFEARPDDVWIATVPRSGTTWTQELIWLVANGLDFEHAQERPLTERFPFFEFPLFVHPKIKEELQEENRDSAEALEFIEKIARPGYEALSEIPRSQRRFIKTHFPFSLMPPSVLEKKCKVIYVVRDPKDVAVSYYHLNRLFRTQGYVGDFERYWHYFQNGLNPWLPYYSHVKEAREHAHLSNVLFLRYEDMLADLPGAINSIASFLECPPKPEDMDRLLDHLSIRSFRENKSVNMHEMAS----VGVLNKGEAGFVRSGAKTAYQPQQEFVENPKLLKSANEWVEQNIKSFKTI---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . : . ::* * **:::.* *:.** * *.: *: . .: * :*: . * *:: :*: ::* : *: *::*: *:***. :*::* . : . . * * : *: . *::: :* * :: : .:..*: . :: : : ::..:: : * . *:* * : . . :.. .: ", "identical_positions": 37, "similar_positions": 80, "identity": "10.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1144", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04694-1", "uniprot_id": "ATTY_RAT", "id": "P04694-1", "name": "Tyrosine aminotransferase", "aln": "MDSYVIQTD--------VDDSLSS---------------------VLD----VHVNIGGRNSVQ-GRKKG----RKARWDVRPSDMSNKTFNPIRAIVDNMKVQPNPNKTVISLSIGDPTVFGNLPTDPEVTQAMKDALDSGKYNGYAPSIGYLSSREEVASY--YHCHEAPLEAKDVILTSGCSQAIELCLAVLANPGQNILIPRPGFSLYRTLAESMGIEVKLYNLLPEKSWEIDLKQLESLIDEKTACLVVNNPSNPCGSVFSKRHLQKILAVAERQCVPILADEIYGDMVFSDCKYEPLANLSTNVPILSCGGLAKRWLVPGWRLGWILIHDRRDIFGNEIRDGLVKLSQRILGPCTIVQGALKSILQRTPQEFYHDTLSFLKSNADLCYGALAAIPGLQPVRPSGAMYLMVGIEMEHFPEFENDVEFTERLIAEQAVHCLPATCFEYPNFFRVVITVPEVMMLEACSRIQEFCEQHYHCA-----EGSQEECDK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8QZR1-1", "uniprot_id": "ATTY_MOUSE", "id": "Q8QZR1-1", "name": "Tyrosine aminotransferase", "aln": "MDSYVIQTN--------VNDSLPS---------------------VLD----VRVNIGGRSSVQ-GRAKG----RKARWNVRPSDMSNKTFNPIRAIVDNMKVKPNPNKTVISLSIGDPTVFGNLPTDPEVTQAMKDALDSGKYNGYAPSIGYLSSREEVASY--YHCPEAPLEAKDVILTSGCSQAIELCLAVLANPGQNILIPRPGFSLYRTLAESMGIEVKLYNLLPEKSWEIDLKQLESLIDEKTACLVVNNPSNPCGSVFSKRHLQKILAVAERQCVPILADEIYGDMVFSDCKYEPMATLSTNVPILSCGGLAKRWLVPGWRLGWILIHDRRDIFGNEIRDGLVKLSQRILGPCTIVQGALKSILQRTPQEFYQDTLSFLKSNADLCYGALSAIPGLQPVRPSGAMYLMVGIEMEHFPEFENDVEFTERLIAEQSVHCLPATCFEYPNFFRVVITVPEVMMLEACSRIQEFCEQHYHCA-----EGSQEECDK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17735-1", "uniprot_id": "ATTY_HUMAN", "id": "P17735-1", "name": "Tyrosine aminotransferase", "aln": "MDPYMIQMS--------SKGNLPS---------------------ILD----VHVNVGGRSSVP-GKMKG----RKARWSVRPSDMAKKTFNPIRAIVDNMKVKPNPNKTMISLSIGDPTVFGNLPTDPEVTQAMKDALDSGKYNGYAPSIGFLSSREEIASY--YHCPEAPLEAKDVILTSGCSQAIDLCLAVLANPGQNILVPRPGFSLYKTLAESMGIEVKLYNLLPEKSWEIDLKQLEYLIDEKTACLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILADEIYGDMVFSDCKYEPLATLSTDVPILSCGGLAKRWLVPGWRLGWILIHDRRDIFGNEIRDGLVKLSQRILGPCTIVQGALKSILCRTPGEFYHNTLSFLKSNADLCYGALAAIPGLRPVRPSGAMYLMVGIEMEHFPEFENDVEFTERLVAEQSVHCLPATCFEYPNFIRVVITVPEVMMLEACSRIQEFCEQHYHCA-----EGSQEECDK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N1TQ92-1", "uniprot_id": "A0A8N1TQ92_DANRE", "id": "A0A8N1TQ92-1", "name": "Tyrosine aminotransferase", "aln": "-MSFVVKMNGVQNNGIHGNGMNGS---------------------IMNGNGVHHVSVRTHVSVNPAKLKAGS--HRQRWNVRPSEMSKKTLNPIRAIVDGMKLTPNPEKPMIALSIGDPTVFGNLPTDDAVLHAMKDAIDSHKYNGYAPSVGYQKSREAVANF--YSCPEAPLEGKDVILASGCSQAIELAISVLCNPGDNILVPRPGFSLYKTLAVSMGIQVKHYNLLPEKSWEIDLQHLESLIDNKTACLIVNNPSNPCGSVFTKEHQQKIISVASRNCIPILADEIYGDMVFPGCDFRALAPLSSDVPILSCGGLAKRWLVPGWRMGWILIHDRNNIFGSGIREGLVKLSQRILGPCTVVQGALESILNETPPEFYQSTISFLKSNSEICFSELSTVSGLNPVMPSGAMYIMVGIEMEHFPEFQNDVEFTERLVTEQSVFCLPATAFEYPNYFRIVVTVPEEMMIEACIRIREFCARHYRPR-----SQDSHELDQ---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VY42-1", "uniprot_id": "Q9VY42_DROME", "id": "Q9VY42-1", "name": "Tyrosine aminotransferase", "aln": "MPSSFANESQFRYQSSRNRASCTSRSPSEPESPAPVTPNCDVVDQALAELQLQSQDIRKQQDLVDTTATSSSSRKRSGWEIKGSKLSLNTHNRIRNIVESLKIKPNPEKPMIPLSIGDPTTFGNLKAADETMKAVLHSLESGKYNGYASTQGHEIARKAVAKYSAHQRPDGEIDANEVVLCSGCSSALEYCILALADRGQNVLVPRPGFCLYYTLAQGLDIEVRYYDLLPDQQWRADLVQLESLIDENTAALLINNPSNPCGSVFDEKHLRELIAICERHYLPIIADEIYEHFVFPGSKHLAVSSLTTEVPVLSCGGLTKRFLVPGWRMGWIIVHDRKNRLRDAIVG-LKNMCGRILGSNTIIQGALPDILTKTPQSYFDGVIDVLHSNAMLAYKMLKQVRGLDPVMPNGAMYMMIGVSIERFPEFKDDTHFVQEMVNEQSVFCLPGSCFEYPGYVRIVLTVPGAMIEEACSRIAEFCDRHYKKESRNFIEHGLLDCDDVAF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . * : .: : .: .. :: *.:: *.:: :* * ** **:.:*: ***:*.:*.*******.**** : . :*: .:::* ******.: *. :*: :*.: : :. ::.::*:* ****.*:: .: .*.: *:*:*:*****.** *** .:.*:*: *:***::.*. ** :** ***::**.*::*********** :.* ::::::. *: :**:***** .:**..... .:: *:::**:******:**:******:***::***.: : . * * ::. ****. *::**** .** .** .::...:..*:**: :.: * : ** ** *.****:*:*:.:*:****::*..*.:.:: **:*.***.:.****.:.*:*:*** *: *** ** *** :**: . . : *. ", "identical_positions": 184, "similar_positions": 174, "identity": "36.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1158", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q13185-1", "uniprot_id": "CBX3_HUMAN", "id": "Q13185-1", "name": "Chromobox protein homolog 3", "aln": "MASNKTTLQKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEAFLNSQKAGKEK-DGTKRKSLSD-SESDDSKSKKKRDAADKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTWHSCPEDEAQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23198-1", "uniprot_id": "CBX3_MOUSE", "id": "P23198-1", "name": "Chromobox protein homolog 3", "aln": "MASNKTTLQKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEDFLNSQKAGKEK-DGTKRKSLSD-SESDDSKSKKKRDAADKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTWHSCPEDEAQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QNF2-1", "uniprot_id": "F1QNF2_DANRE", "id": "F1QNF2-1", "name": "", "aln": "-------MVNMGKKQAGKSKK-EVQEIEEFVVEKVMDQRVVNGKVEFFLKWKGFTDADNTWEPEENLDCPELIAAFLESQKGVVEKPEAVKRKSSTDEPETEESKAKRKKEMSDKPRGFARNLEPERIIGATDSSGELMFLMKWKDSDEADLVPAREANTRCPQIVIAFYEERLTWHSCPEDEQQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :***** ***** * * ********:*:********:************************** **:***. ** :..**** :* .*:::**:*:*:: :********.*:***************************** *:*** :********************** *", "identical_positions": 137, "similar_positions": 24, "identity": "74.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1175", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P21926-1", "uniprot_id": "CD9_HUMAN", "id": "P21926-1", "name": "CD9 antigen", "aln": "-MPVKGGTKCIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQETNNNNSSFYTGVYILIGAGALMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDEVIKEVQEFYKDTYNKLK-TKDEPQRETLKAIHYALNCCGLAGGVEQFISDICPKKDVLETFTVKSCPDAIKEVFDNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIRRNREMV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QBC5-1", "uniprot_id": "E9QBC5_DANRE", "id": "E9QBC5-1", "name": "Tetraspanin", "aln": "MAALTGGEMCVKYLMFVFNFIFWIAGTAVLAVGLWLRFDPKTKSLFEGE--NSPYVFYTGVYILIAAGALMMVVGFFGCCGAIQESPCMLGLFFFFLLVIFAVEVAAGIWGFSNQTKVTEDITTFYRQTYDTYQQSKQEALKKTLRLFQHGLNCCGPSGNMQESLDETCPKKEGLDNLIIKSCPDAIDEVFNSKLHIIGGVGIATGVIMIFGMIFSMMLCCAIRKTREIV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:.** *:***:* ******:** ****:*******.:***:** * *. *********.******:***:*****:*** ******* *******:*:**.***:*:: :* ::: **::**:. : :*:*. ::**: :::.***** :*.::: :.: ****: *:.: :*******.***:.*:****.***. .*:*********:******:.**:*", "identical_positions": 137, "similar_positions": 65, "identity": "59.57%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1178", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M171-1", "uniprot_id": "F1M171_RAT", "id": "F1M171-1", "name": "", "aln": "---MAVLASWVWILTGCFSPAVAEISNVVSLYPPLWEDSPEQISDYRMEDGKYVINPWVLTDRMGMYRILLNETATYFARYGPENEQNLLWGLPLQFGWQYQTGRLADPTG--MTDCGKELEESLCVSVNSWWADVNYYLSVLPFLAAVDSGMTGLSPNQIMILPPLKDQMRFCYNVSDCRSALPKTMDKWRDFFQYMQLPS-------SDFDGLLKKLWDAHTSSLEYPTRAFVDRYDFYSDQEANFGENWAIVVYYLGAARLPTTLNRSHSFQRGLPTRVLDDTDITPFIPDFTPLQNKVLVTLKLFGNTDRLSGSLSLTIWESLMSTKFARGLFLKAFEEFLGTSP-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C6C9-1", "uniprot_id": "LEG1H_MOUSE", "id": "Q8C6C9-1", "name": "Protein LEG1 homolog", "aln": "---MAVLASWVWVLAGCFCAAVAEVSDSSDPYPPLWEDSPEQLSDYMMEDGNYIINPWVYTDRMGMYRILLEETAMYFAKYGPENEQNLLWGLPLQFGWQYQSGRLADPTG--MTDCGNELNESLCVSVDSWWADINYYLSVIPFLAAVDSGITGISPNQITILPPPKDQMRFCYNVSDCQSAVPGTMNRWRDFFQYMQLNS-------SDFDGLLNYLWEAHASSLDYPTSAFGDRYNFYSEKEANFEENWAIAVNYLAAARLPTTQNRTYSFQRGLPPRVLVDTDIAPFIPDFTPLQNEVLVSLKLLGDTDRNSGSLSLTLWENLMSTKLARTLFLKAFEEFLATSS-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P5S2-1", "uniprot_id": "LEG1H_HUMAN", "id": "Q6P5S2-1", "name": "Protein LEG1 homolog", "aln": "---MAFLPSWVCVLVGSFSASLAGTSNLSETEPPLWKESPGQLSDYRVENSMYIINPWVYLERMGMYKIILNQTARYFAKFAPDNEQNILWGLPLQYGWQYRTGRLADPTR--RTNCGYESGDHMCISVDSWWADLNYFLSSLPFLAAVDSGVMGISSDQVRLLPPPKNERKFCYDVSSCRSSFPETMNKWNTFYQYLQSPF-------SKFDDLLKYLWAAHTSTLADNIKSFEDRYDYYSKAEAHFERSWVLAVDHLAAVLFPTTLIRSYKFQKGMPPRILLNTDVAPFISDFTAFQNVVLVLLNMLDNVDKSIGYLCT------EKSNVYRDHSESSSRSYGNNS------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PF61-1", "uniprot_id": "LEG1A_DANRE", "id": "A5PF61-1", "name": "Protein leg1a", "aln": "MSEMGFLRSVAAVLLLAVFSHAAVVTENG--LPIQWGKAPSDLSHLPISDTGVQVNPWDYSQRMTMYKMLINATNAYMSSMGPGEQENPLWSLPLQLGWKLKSGRLADPTLDSSSTCGSEASDPVCISPLSWFACVNYYLSVLPFLAAVETGVVSSGGHQVLIQVPAEVAQDYCSSYSDCSTKHPNAMAKWHLFFQSLRQVSQSEDSDFNKKDSILGLMWAAEEESLQTASGACTERQKLYSSPEVSFQQSWLNSAAFVSAAHFHANIERSEKFMAPLPSRVLQEADSPPNIADLSTEENHTLYIFGWMNSVNQLLGGSLVNLWRKAMCSAQAREKGQALLHDLILDPKFPGSSLWSILSEMSTSC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *..* * . :* .. . * :: * * .:* ::*. :.: :*** :** **::::: * *:: .* :::* **.**** **: ::******* : ** * : :*:* **:* :**:** :******::*: . . .*: : * : :* . *.* : * :* :*. *:* :: .. *.:* :* *. .:* : :* . **. *. * ..* . .:.*. : :. *: .* :*.*:* ::* .* *.*::. :* .* : :...:: * : * .. . ", "identical_positions": 89, "similar_positions": 109, "identity": "24.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1187", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P21643-1", "uniprot_id": "T23O_RAT", "id": "P21643-1", "name": "Tryptophan 2,3-dioxygenase", "aln": "MSGCPFSGNSVGYTLKNLSMEDNEEDGAQTGVNRASKGGLIYGDYLQLEKILNAQELQSEIKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGHVRDERNMLKVMTRMHRVVVIFKLLVQQFSVLETMTALDFNDFREYLSPASGFQSLQFRLLENKIGVLQSLRVPYNRKHYRDNFEGDYNE-LLLKSEQEQTLLQLVEAWLERTPGLEPHGFNFWGKFEKNILKGLEEEFLKIQAKKDSEEKEEQMAEFRKQKEVLLCLFDEKRHDYLLSKGERRLSYRALQGALMIYFYREEPRFQVPFQLLTSLMDIDTLMTKWRYNHVCMVHRMLGSK-AGTGGSSGYYYLRSTVSDRYKVFVDLFNLSSYLVPRHWIPKMNPIIHKFLYTAEYSDSSYFSS-DESD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48776-1", "uniprot_id": "T23O_MOUSE", "id": "P48776-1", "name": "Tryptophan 2,3-dioxygenase", "aln": "MSGCPFAGNSVGYTLKNVSMEDNEEDRAQTGVNRASKGGLIYGNYLQLEKILNAQELQSEVKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGHVRDERNMLKVIARMHRVVVIFKLLVQQFSVLETMTALDFNDFREYLSPASGFQSLQFRLLENKIGVLQSLRVPYNRKHYRDNFGGDYNE-LLLKSEQEQTLLQLVEAWLERTPGLEPNGFNFWGKFEKNILKGLEEEFLRIQAKTDSEEKEEQMAEFRKQKEVLLCLFDEKRHDYLLSKGERRLSYRALQGALMIYFYREEPRFQVPFQLLTSLMDIDTLMTKWRYNHVCMVHRMLGTK-AGTGGSSGYHYLRSTVSDRYKVFVDLFNLSTYLVPRHWVPKMNPIIHKFLYTAEYSDSSYFSS-DESD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48775-1", "uniprot_id": "T23O_HUMAN", "id": "P48775-1", "name": "Tryptophan 2,3-dioxygenase", "aln": "MSGCPFLGNNFGYTFKKLPVEGSEEDKSQTGVNRASKGGLIYGNYLHLEKVLNAQELQSETKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGHVRDERNMLKVVSRMHRVSVILKLLVQQFSILETMTALDFNDFREYLSPASGFQSLQFRLLENKIGVLQNMRVPYNRRHYRDNFKGEENE-LLLKSEQEKTLLELVEAWLERTPGLEPHGFNFWGKLEKNITRGLEEEFIRIQAKEESEEKEEQVAEFQKQKEVLLSLFDEKRHEHLLSKGERRLSYRALQGALMIYFYREEPRFQVPFQLLTSLMDIDSLMTKWRYNHVCMVHRMLGSK-AGTGGSSGYHYLRSTVSDRYKVFVDLFNLSTYLIPRHWIPKMNPTIHKFLYTAEYCDSSYFSS-DESD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A7MBU6-1", "uniprot_id": "T23OA_DANRE", "id": "A7MBU6-1", "name": "Tryptophan 2,3-dioxygenase A", "aln": "MSGCPYFQRKFLSTSKQHLKEE-ENDEAQTGINKASKGGLIYGDYLQLDKIVTSQVLQSELKGNKIHDEHLFIVTHQAYELWFKQVLWELDSVREIFISGHVRDERNMLKVNTRIHRIVMIFRLLLDQFAVLETMTALDFYDFREYLSPASGFQSLQFRLLENKIGVPHNQRVPYNRRHYRDNFRDQESE-LLLHSEQEPTLLQLVEQWLERTPGLEEDGFNFWGKLEKNIFEGLRREKEHIEQKPASERKEEMLAELIKQRDIFLSLFDEKRHDHLVSTGQRRLSYKALQGALMIYFYREEPRFQVPFQLLTSLMDIDTLMTKWRYNHVCMVHRMIGSK-DGTGGSSGYQYLRSTVSDRYKVFVDLFNLATFLIPRDWVPKLDPSEHTFLYMAECCDSSYCSSSDDSD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20351-1", "uniprot_id": "T23O_DROME", "id": "P20351-1", "name": "Tryptophan 2,3-dioxygenase", "aln": "MS-CPYAGN--------------GNDHDDSAVPLTTEVGKIYGEYLMLDKLLDAQCMLSEEDKRPVHDEHLFIITHQAYELWFKQIIFEFDSIRDMLD-AEVIDETKTLEIVKRLNRVVLILKLLVDQVPILETMTPLDFMDFRKYLAPASGFQSLQFRLIENKLGVLTEQRVRYN-QKYSDVFSDEEARNSIRNSEKDPSLLELVQRWLERTPGLEESGFNFWAKFQESVDRFLEAQVQSAMEEPVEKAKNYRLMDIEKRREVYRSIFDPAVHDALVRRGDRRFSHRALQGAIMITFYRDEPRFSQPHQLLTLLMDIDSLITKWRYNHVIMVQRMIGSQQLGTGGSSGYQYLRSTLSDRYKVFLDLFNLSTFLIPREAIPPLDETIRKKLINKSV-------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **: . :* ::.: ::: * ***:** *:*:: :* : ** . . :*******:***********:::*:**:*::: ..* ** : *:: *::*: :*::**::*..:*****.*** ***:**:************:***:** . ** ** ::* * * .: . : :**:: :**:**: ********* *****.*:::.: . *. : : .: *: : :: *:::: .:** *: *: *:**:*::*****:** ***:****. *.**** *****:*:******** **:**:*:: ******** *****:*******:*****:::*:**. :* :: :. * . ", "identical_positions": 185, "similar_positions": 113, "identity": "45.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1201", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64285-1", "uniprot_id": "CEL_MOUSE", "id": "Q64285-1", "name": "Bile salt-activated lipase", "aln": "---------MGRLEVLFLGLTCCLAAACAAKLGAVYTEGGFVEGVNKKLSLLGGDSVDIFKGIPFAT----AKTLENP-QRHPGWQGTLKATNFKKRCLQATIT------------------QDNT--YGQEDCLYLNIWVPQGRKQVSHNLPVMVWIYGGAFLMGSGQGANFLKNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNFGLRDQHMAIAWVKRNIAAFGGDPDNITIFGESAGAASVSLQTLS-PYNKGLIRRAISQSG-MALSPWAIQKNPLFWAKTIAKKVGCPTEDTGK---MAACLKITDPRALTLAYKLPVKKQ-EYPVVHYLAFIPVIDGDFIPDDPINLYNN--TADIDYIAGINNMDGHLFATIDVPAVDKTKQTVTEEDFYR---LVSGHTVAKGLKGAQ-----ATFDIYTESWAQDPSQENMKKTVVAFETDVLFLIPTEIALAQHKAHAKSAKTYSYLFSHPSRMPIYPKWMG--------ADHADDLQYVFGKPFATP-LGYRPQDRAVSKAMIAYWTNFARSGDPNMGNSPVPTHWYPYTLENGNYLDITKTITSASMKEHLREKFLKFWAVTFEVLPTVTGDQD-----------TLTPPEDDSEVAPDPPSDDSQVVPVPPTD-----------------------------------------------------------------------------------------------------------------------------------------------DSVEAQMPATIGF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07882-1", "uniprot_id": "CEL_RAT", "id": "P07882-1", "name": "Bile salt-activated lipase", "aln": "---------MGRLEVLFLGLTCCLAAACAAKLGAVYTEGGFVEGVNKKLSLLGGDSVDIFKGIPFAT----AKTLENP-QRHPGWQGTLKATDFKKRCLQATIT------------------QDDT--YGQEDCLYLNIWVPQGRKQVSHDLPVMVWIYGGAFLMGSGQGANFLKNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNFGLRDQHMAIAWVKRNIAAFGGDPDNITIFGESAGAASVSLQTLS-PYNKGLIRRAISQSG-VALSPWAIQENPLFWAKTIAKKVGCPTEDTAK---MAGCLKITDPRALTLAYRLPLKSQ-EYPIVHYLAFIPVVDGDFIPDDPINLYDN--AADIDYLAGINDMDGHLFATVDVPAIDKAKQDVTEEDFYR---LVSGHTVAKGLKGTQ-----ATFDIYTESWAQDPSQENMKKTVVAFETDILFLIPTEMALAQHRAHAKSAKTYSYLFSHPSRMPIYPKWMG--------ADHADDLQYVFGKPFATP-LGYRAQDRTVSKAMIAYWTNFAKSGDPNMGNSPVPTHWYPYTTENGNYLDINKKITSTSMKEHLREKFLKFWAVTFEMLPTVVGDHTP---PEDDSEAAPVPPTDDSQGGPVPPTDDSQTTPVPPTDNSQA------------------------------------------------------------------------------------------------------------------------------------------GDSVEAQMPGPIGF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19835-1", "uniprot_id": "CEL_HUMAN", "id": "P19835-1", "name": "Bile salt-activated lipase", "aln": "---------MGRLQLVVLGLTCCWAVASAAKLGAVYTEGGFVEGVNKKLGLLG-DSVDIFKGIPFAAP---TKALENP-QPHPGWQGTLKAKNFKKRCLQATIT------------------QDST--YGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLS-PYNKGLIRRAISQSG-VALSPWVIQKNPLFWAKKVAEKVGCPVGDAAR---MAQCLKVTDPRALTLAYKVPLAGL-EYPMLHYVGFVPVIDGDFIPADPINLYAN--AADIDYIAGTNNMDGHIFASIDMPAINKGNKKVTEEDFYK---LVSEFTITKGLRGAK-----TTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYPKWVG--------ADHADDIQYVFGKPFATP-TGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYWTLTYLALPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPPTDDSKEAQMPAVIRF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PFJ8-1", "uniprot_id": "A0A8M1PFJ8_DANRE", "id": "A0A8M1PFJ8-1", "name": "Carboxylic ester hydrolase", "aln": "---------MAMLG-VFISAVLFLGTAQGASLGAVLTEGGMVQGKSRSVGLFR--YMDTFKGIPFAAP---PKRFEKP-VAHPGWEGVLKTTDYRKRCLQLNLL------------------ATDV--IGSEDCLYLNIWVPQGR-TVSSNLPVMVFIYGGAFLLGGGQGANFLDNYLYDGEEMADRGNVIVVTFNYRVGALGFMSTGDDGIPGNYGLWDQHAAISWVHRNIKAFGGNPDNITLFGESAGAASVNFQIIT-PKNKGMIRRAISQSG-VALCPWAISRNPRQFAEEIATKVGCPIDSG-----MADCLKRADPKAVTLAGKLKLTSSPDAPIVHNLYLSPVIDGDFIPDEPETLFGN--AADIDYIAGVNDMDAHIFATIDIPSINNALTTTPVEEVQA---LATALSRDRGQDAGI-----ATFQEYTVNWGDKPNKEKVKQTVVELETDYMFLVPTQAALYLHTDNAKSARTFSYLFTESSRIPVFPLWMG--------ADHADELQYVFGKPFATP-LGYFPRHRDVSKYMIAYWSNFAQTGDPNKGESKVPVTWPEFSNPGHQYLDINNKMNKNNVKQMLRTRLVYYWTTVFASYPTVRN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZA97-1", "uniprot_id": "A1ZA97_DROME", "id": "A1ZA97-1", "name": "Carboxylic ester hydrolase", "aln": "------------MLFAGFGVLLFVAVAVGDSLDVCLEDMGCMRG--TLMPGYQSGEFEAFMGIPFAQPPVGPLRLKNP-VPNEPWEGVLDAGAAKDSCIQRSYF------------------AKEWGLMGVEDCLYLNVYRPKNR--AEDKLPVMVYIHGGGFFSGSAHPMASGPEYLMDTN------KVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQRLALQWIQKHIATFGGDPKKVTVLGHSAGGISAHLHMIS-PNSKGLFQNSMSLTGTMFLSAMKILKDPLSQARRLGKELAIDQAESLSSQDLAEALRNVCPKKLLVSVDSLKVWDNMPHLTTLPVLEAPSPDAFLVEDPLDAHRAGRINQMPWILSLSSRAGEGSLFIMRAFINPKLRAEFNENFLEHMALLLNLPEGTPVQMVS-----EILDAYDFKGDSLNNDTMLKLAEISGDFNFYYPIYETISSYVTYANLEENPLFIYIFEFAGLNSITKFFAGTTDDYGLGAVHMDDGLHTIRIPVSFDDFPKDSEDAKVIQRMSSLMTDFAKTGVFHEESICKVSDFKEQGMCNYLHFGGNKEKYLEDIRNSITLTAFPIWKKLFA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W1B3-1", "uniprot_id": "Q9W1B3_DROME", "id": "Q9W1B3-1", "name": "Carboxylesterase type B domain-containing protein", "aln": "MDCRANFLAYLAVFLHLVSDYCFVPVQCVDAPFIHIPGNGVISG--TYLKMFRTQNIKAYLGIRYAH----ARRFQPPDIELTPWKGIFNATVFQPDCWQNAMPSVGKETEQILKIIQSDSSAQDAERKYEENCLYLNVFVPDGLP-EINGYAVVVWIHSGDFSTGSPADVEPFQ--------LVFKQKVIVVTFSYRLNIFGFFTTDDGEAQGNYGLMDQSAALYWVKKNINFFGGDSNRITLMGHDAGAVSVALHMTSGEWSKGGFHKAIIMSG-NPLSTVKMPYEYEGSLDQVSSTFACPRRPTSM---FIQCLKRIDAKRLSENLPQVSWGP----VVDFGLSNTSYP--FIENQPEILFKKGSYHRVPVIIGVTDMEEVLTLFKDN--LDTDISPSDLEGFYTDIAVTDMHKLVRNYEWCSNYELISDAINFMYANDSDTDAKKANKHIISAHTEKFYITPMQTFADLISNDSQ-VYSYLFRMRPRSVLQDLPSWIS--------VPKYFDQIFVWGNPYMTNSVDWKSTDKKIADIIMTLWANFAKTSNPTKSN--VYVKWNAMTPNNDSVLLIDESFNTDNLLNNQRINFWRSLYPKILVFSADCCNSTFSGSGLVIATSVPILCTLSIIVNIF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. . * : * : .. : ** :* . :: * *:* :.: : * * . *:*****:: *.. .*:::*:.* * *. :*::**:.**:. :**::*.* **:*: ** *: *::::* ***:...:*::*..**. *. :: : .** ::.:: :* *.. : : :. .. : .*: .: : : . *: :* . : : . .. :: * . : : . . : : . : : . : : : : . : . . : : .. * . . : . : : ::**::. . : . : : .: . ", "identical_positions": 58, "similar_positions": 138, "identity": "7.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1226", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15559-1", "uniprot_id": "NQO1_HUMAN", "id": "P15559-1", "name": "NAD(P)H dehydrogenase [quinone] 1", "aln": "MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKLKDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQF--------------PLQWFGVPAILKGWFERVFIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFCGFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMKKEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8PW65-1", "uniprot_id": "A0A2R8PW65_DANRE", "id": "A0A2R8PW65-1", "name": "NAD(P)H dehydrogenase [quinone] 1", "aln": "MAQKTALIVYAHQSPASFNAAARDVAVQALTKKGYKVLVSDLYAMKFKASATAEDIKGDLQNPEHFVYNNEMMVAWKEGRLSDDVAEEQHKVEQADLIIFQLDRRRIICFVMSLQYPLYWFTIPAIMKGWIDRVLTQGFAFSMQNMYDNGIFKNKRAMLSFTTGGMESMYKDDSLHGDINILLWPLQNGVLRFCGFQVLAPQIFWSPAYTPPEGRAAMLDGWRERLGGVFEEKPLSFAPSEYFDLSFQAGFCLRPEVKDKLASEPYGITTAHHLGKPLPPNNQTKPKQN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : **** **.. :*** * ::.*. **.***::*: ******:*:. : :**.*.*::* :* * * ::*:***:** *:. **:*:* ***:***: ** ** :***:***::**: **:: ***:* *:.*:*:**:**** ***. :.:***:*::***:*.*:*:******* **: :* .:**.:.* :*:**::** .:::*.** ****. ***.***** :: **:*: .: :*::..*****.:*.:** *.:: ", "identical_positions": 136, "similar_positions": 93, "identity": "47.06%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1233", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZF39-1", "uniprot_id": "D3ZF39_RAT", "id": "D3ZF39-1", "name": "UDP-N-acetylhexosamine pyrophosphorylase", "aln": "--------------------------------------MNVNDLRQRLSAAGQQHLLQFWSELSEAQQGELYMELQAMN----FEELNSFFQKAVGEFDRSSHQEKVDARMEPVPRQVLGSATRD-QDQLQAWESEGLSQISQNKVAVLLLAGGQGTRLGVTYPKGMYDVGLPSHKTLFQIQAERILKLQQLAEKQYGNKCTIPWYIMTSGRTMESTKEFFTKHKFFGLKKENVVFFQQGMLPAMSFDGK-VILEEKNKVSMAPDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLKDVVNVYEPQLQHHVAQKKIPYVDSQ-GHLIKPDKPNGIKMEKFVFDIFQFA--KKFVVYEVLREDEFSPLKNADSQNGKDNPTTARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSATNGKSETITADVNHNLKDANDVPIQCEISPLISYAGEGLEGYVADKDFHAPLIIDENGVHELVKNGI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YN5-1", "uniprot_id": "UAP1_MOUSE", "id": "Q91YN5-1", "name": "UDP-N-acetylhexosamine pyrophosphorylase", "aln": "--------------------------------------MNVNDLKQRLSQAGQEHLLQFWNELSEAQQVELYMELQAMN----FEELNSFFRKAIGEFDRSSHQEKVDARMEPVPRQVLGSATRD-QEQLQAWESEGLSQISQNKVAVLLLAGGQGTRLGVSYPKGMYDVGLPSHKTLFQIQAERILKLQQLAEKHHGNKCTIPWYIMTSGRTMESTKEFFTKHKFFGLKKENVVFFQQGMLPAMSFDGK-IILEEKNKVSMAPDGNGGLYRALAAQNIVEDMEQRGICSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEYSEISLATAQRRSSDGRLLFNAGNIANHFFTVPFLKDVVNVYEPQLQHHVAQKKIPYVDSQ-GYFIKPDKPNGIKMEKFVFDIFQFA--KKFVVYEVLREDEFSPLKNADSQNGKDNPTTARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSATNGKSEAITADVNHNLKDANDVPIQCEISPLISYAGEGLEGYVADKEFHAPLIIDENGVHELVKNGI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16222-1", "uniprot_id": "UAP1_HUMAN", "id": "Q16222-1", "name": "UDP-N-acetylhexosamine pyrophosphorylase", "aln": "--------------------------------------MNINDLKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMN----FEELNFFFQKAIEGFNQSSHQKNVDARMEPVPREVLGSATRD-QDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTKHKYFGLKKENVIFFQQGMLPAMSFDGK-IILEEKNKVSMAPDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLRDVVNVYEPQLQHHVAQKKIPYVDTQ-GQLIKPDKPNGIKMEKFVFDIFQFA--KKFVVYEVLREDEFSPLKNADSQNGKDNPTTARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSATNGKSETITADVNHNLKDANDVPIQCEISPLISYAGEGLESYVADKEFHAPLIIDENGVHELVKNGI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4INK2-1", "uniprot_id": "A0A0R4INK2_DANRE", "id": "A0A0R4INK2-1", "name": "UDP-N-acetylhexosamine pyrophosphorylase", "aln": "--------------------------------------MDIHKLAERLAKAGQSHVIQFWDQLSPEEQGEMSLDLESMN----FLEINNFFKSAMKTSGQSS-QEKVDTRMEPVPRDVLGSVTRD-RECLKEWEKEGLRCIAENKVAVLLLAGGQGTRLGVSFPKGMYDVGLPSHKTLFQIQAERIRKLEQLAEKQHSRKCCIPWYIMTSGRTMDMTKDFFIQHKYFGLKEENVVFFQQGMLPAMDFNGK-IILEGKCKLAMAPDGNGGLYRALGTQNIVKDMETRGISYIHVYCVDNILVKVADPAFIGFCTLKGADCGAKVVEKTNPTEAVGVVCKVDGRYQVVEYSEITLATAEKRSTDGRLMFNAGNIANHFFTLTFLREIVRTHEPQLQHHVAQKKIPYVNTE-GQLIKPDKPNGIKMEKFVFDIFQFA--KKFVVYEVLREDEFSPLKNADSQDGKDNPTTARHALMSLHHRWILNAGGHFVDENGTHIPAIPRAGPAG---TVTPEVSQNLKDGTDLPIKCEISPLVSYGGEGLEHLVNEKVFQPTLIINESGVHELVKNGL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y0Z0-1", "uniprot_id": "Q9Y0Z0_DROME", "id": "Q9Y0Z0-1", "name": "UDP-N-acetylglucosamine diphosphorylase", "aln": "MGRSNFSSHHQQTHVRRHRNAGGATSKSPNAAKTSPTMTDYLSLHSRLAQVGQEHLLKFWPELTNDERIDLVRDIEELN----LDEIKLYFDRATVSMNENG--IKLDDRLQPLPEGKLISIARAPLEKLDAYRDEGLLQISNGHVAVLLMAGGQGTRLGFDHPKGMYDVGLQSRKTLFRIQAERILKLEELAQEANGKRGHITWYIMTSEHTVQPTYDYFVANNFFGLKAENVLLFEQGSLPCFEYDGR-IILDEKHRVARAPDGNGGIYRAMKRQGILDDMQKRGVLYLHAHSVDNILIKVADPVFIGYCVQEKADCAAKVVEKAAPNEAVGVVAIVDGKYQVVEYSEISAKTAEMRNSDGRLTFSAGNICNHFFSSNFLQKIGSTYEQELKLHVAKKKIPFVDNA-GKRLTPDKPNGIKIEKFVFDVFEFA--QKFVAMEVPRDEEFSALKNSD-AAGKDCPSTARSDLHRLHKKYIEGAGG-----------------------IVHGEV-------------CEISPFVTYAGENLASHVEGKSFTSPVYLRDS--RDPLHGHL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43123-1", "uniprot_id": "UAP1_YEAST", "id": "P43123-1", "name": "UDP-N-acetylglucosamine pyrophosphorylase", "aln": "----------------------------------------MTDTKQLFIEAGQSQLFHNWESLSRKDQEELLSNLEQISSKRSPAKLLEDCQNAIKFSLANS-SKDTGVEISPLPPTSYESLIGN-SKKENEYWRLGLEAIGKGEVAVILMAGGQGTRLGSSQPKGCYDIGLPSKKSLFQIQAEKLIRLQDMVKDK---KVEIPWYIMTSGPTRAATEAYFQEHNYFGLNKEQITFFNQGTLPAFDLTGKHFLMKDPVNLSQSPDGNGGLYRAIKENKLNEDFDRRGIKHVYMYCVDNVLSKIADPVFIGFAIKHGFELATKAVRKRDAHESVGLIATKNEKPCVIEYSEISNELAEAKDKDGLLKLRAGNIVNHYYLVDLLKRDLDQWCENMPYHIAKKKIPAYDSVTGKYTKPTEPNGIKLEQFIFDVFDTVPLNKFGCLEVDRCKEFSPLKNGP-GSKNDNPETSRLAYLKLGTSWLEDAGA-----------------------IVKDGV------------LVEVSSKLSYAGENLS-QFKGKVFDRSGIVLEK----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .**.:::: * .* :: :: ::: :. :: * .. . . .:.*:* * . . : ** *.:..***:*:********* *** **:** *:*:**:****:: :*:::.:. : *.****** * * :* :::***: *:: :*:** **.:. *: .::. .:: :******:***: : : .*:: **: :: :.***:* *:*** ***:. . : .:*.*.* . *.**::. : *:*****: *: :..** * : **** **:: :*: :: *:*:**** :. * .* :*****:*:*:**:*: . :** ** * .***.***. :* * *:* * :: .**. : * *:*. ::*.**.* . * * . : :. ", "identical_positions": 151, "similar_positions": 148, "identity": "26.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1257", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLJ3-1", "uniprot_id": "AL9A1_RAT", "id": "Q9JLJ3-1", "name": "4-trimethylaminobutyraldehyde dehydrogenase", "aln": "--------------MSTGTFVVSQPLNYRGGARVEPVDASGTEKAFEPATGREIATFKCSGEKEVNLAVENAKAAFKIWSKKSGLERCQVLLEAARIIKERRDEIAIMETINNGKSIFEARLDVDTSWQCLEYYAGLAASMAGEHIQLPGGSFGYTRREPLGVCLGIGAWNYPFQIACWKSAPALACGNAMIFKPSPFTPVSALLLAEIYTKAGAPNGLFNVVQGGAATGQFLCQHRDVAKVSFTGSVPTGMKIMEMAAKGIKPITLELGGKSPLIIFSDCNMKNAVKGALLANFLTQGQVCCNGTRVFVQKEIADAFTKEVVRQTQRIKIGDPLLEDTRMGPLINAPHLERVLGFVRSAKEQGATVLCGGEPYAPEDPKLKHGYYMTPCILTNCTDDMTCVKEEIFGPVMSILTFETEAEVLERANDTTFGLAAGVFTRDIQRAHRVAAELQAGTCYINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCVEMGDVESAF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLJ2-1", "uniprot_id": "AL9A1_MOUSE", "id": "Q9JLJ2-1", "name": "4-trimethylaminobutyraldehyde dehydrogenase", "aln": "--------------MSTGTFVVSQPLNYRGGARVEPVDASGTEKAFEPATGRVIATFACSGEKEVNLAVENAKAAFKLWSKKSGLERCQVLLEAARIIKERKDEIATVETINNGKSIFEARLDVDTCWQCLEYYAGLAASMAGEHIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIACWKSAPALACGNAMIFKPSPFTPVSALLLAEIYTKAGAPPGLFNVVQGGAATGQFLCHHREVAKISFTGSVPTGVKIMEMSAKGVKPITLELGGKSPLIIFSDCNMENAVKGALMANFLTQGQVCCNGTRVFVQKEIADKFINEVVKQTQKIKLGDPLLEDTRMGPLINAPHLERVLGFVKLAKEQGATVLCGGEVYVPEDPKLKHGYYMTPCILTNCRDDMTCVKEEIFGPVMSILTFGTEAEVLERANDTTFGLAAGVFTRDIQRAHRVAAELQAGTCYINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCVEMGDVESAF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49189-1", "uniprot_id": "AL9A1_HUMAN", "id": "P49189-1", "name": "4-trimethylaminobutyraldehyde dehydrogenase", "aln": "--------------MSTGTFVVSQPLNYRGGARVEPADASGTEKAFEPATGRVIATFTCSGEKEVNLAVQNAKAAFKIWSQKSGMERCRILLEAARIIREREDEIATMECINNGKSIFEARLDIDISWQCLEYYAGLAASMAGEHIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYSEAGVPPGLFNVVQGGAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAKGIKPVTLELGGKSPLIIFSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKFTEEVVKQTQRIKIGDPLLEDTRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVPEDPKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAGVFTRDIQRAHRVVAELQAGTCFINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCVEMGDVESAF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVB2-1", "uniprot_id": "A9A1A_DANRE", "id": "Q7ZVB2-1", "name": "4-trimethylaminobutyraldehyde dehydrogenase A", "aln": "MAQQPLLSLPEFQSVSTGTLVVKEPLNFWGGARVKPRDTKNSEPVYEPATGRVLCDMIPCGEEEVDQAIKSAHSAYLKWSQLSGMERSRIMLEAARIIRERRNAIAKAEVANNGKSITEAEVDIDVAWQCIEYYAGIAPTLSGQHIQLPGGSFAYTRREPLGVCVGIGAWNYPFQIAAWKSAPALACGNAMVFKPSPMTPVTAVMLAEIYKEAGVPDGLFNVVQGGAETGSLLCHHPMVAKVSFTGSVPTGKKVMEMAAKSVKQVTLELGGKSPLIIFKDCELENAIKGALMANFLTQGEVCCNGTRVFVQREIMPKFLEEVVKRTKAISVGDPLCEGTRMGALISKPHMEKVLGFIKQAKEQGGKVLCGGERFVPNDPKLKDGYFVSPCVLDNCRDDMTCVKEEIFGPVMSVLPFDTEEEVLQRANNTTFGLASGVFTRDIARAHRVAANLQAGTCYINNYNVGPVEVPFGGYKMSGFGRENGTVTIEYYSQLKTVVVEMGDVESLF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :****:**.:***: *****:* *:..:* .:****** :. : .**:**: *::.*::*: **: **:**.:::*******:**.: ** * ****** **.:*:* .***:*****:*.:::*:*********.**********:************.*************:*****:***:*::*****.:**.* ********** **.:**:* ***:********* *:***:**.:* :*************.**:::**:****:*******:***********:** * :***::*: *.:**** *.****.**. **:*:****:: *****..*****: :.*:*****.**:: **:* ** ****************:*.* ** ***:***:******:******* *****.*:******:******.***:****** ******** ************ ******** *", "identical_positions": 346, "similar_positions": 105, "identity": "68.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1259", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06866-1", "uniprot_id": "HPT_RAT", "id": "P06866-1", "name": "Haptoglobin", "aln": "MRALGAVVTLLLWG-QLFAVELGNDATDIEDDSCPKPPEIANGYVEHLVRYRCRQFYKLQTEGDGIYTLNSEK-----------------------------------------------------------QWVNPAAGDKLPKCEAVCGKPKHPVDQVQRIIGGSMDAKGSFPWQAKMISRHGLTTG----ATLISDQWLLTTAQNLFLNHSENATAKDIAPTLTLYVGKNQ--------LVEIEKVVLHPERS-----VVDIGLIKLKQKVLVTEKVMPICLPSK-DYVAP--GRMGYVSGWGRNVNFRFTERLKYVMLPVADQEKCELHYEKSTVPEKKGAVSPVGVQPILNKHTFCAGLTKYEEDTCYGDAGSAFAVHDTEEDTWYAAGILSFDKSCAVAEYGVYVRATDLKDWVQETMAKN--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61646-1", "uniprot_id": "HPT_MOUSE", "id": "Q61646-1", "name": "Haptoglobin", "aln": "MRALGAVVTLLLWG-QLFAVELGNDAMDFEDDSCPKPPEIANGYVEHLVRYRCRQFYRLRAEGDGVYTLNDEK-----------------------------------------------------------QWVNTVAGEKLPECEAVCGKPKHPVDQVQRIIGGSMDAKGSFPWQAKMISRHGLTTG----ATLISDQWLLTTAKNLFLNHSETASAKDITPTLTLYVGKNQ--------LVEIEKVVLHPNHS-----VVDIGLIKLKQRVLVTERVMPICLPSK-DYIAP--GRVGYVSGWGRNANFRFTDRLKYVMLPVADQDKCVVHYENSTVPEKKNLTSPVGVQPILNEHTFCAGLTKYQEDTCYGDAGSAFAIHDMEEDTWYAAGILSFDKSCAVAEYGVYVRATDLKDWVQETMAKN--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00738-1", "uniprot_id": "HPT_HUMAN", "id": "P00738-1", "name": "Haptoglobin", "aln": "MSALGAVIALLLWG-QLFAVDSGNDVTDIADDGCPKPPEIAHGYVEHSVRYQCKNYYKLRTEGDGVYTLNDKKQWINKAVGDKLPECEADDGCPKPPEIAHGYVEHSVRYQCKNYYKLRTEGDGVYTLNNEKQWINKAVGDKLPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTG----ATLINEQWLLTTAKNLFLNHSENATAKDIAPTLTLYVGKKQ--------LVEIEKVVLHPNYS-----QVDIGLIKLKQKVSVNERVMPICLPSK-DYAEV--GRVGYVSGWGRNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEYGVYVKVTSIQDWVQKTIAEN--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00739-1", "uniprot_id": "HPTR_HUMAN", "id": "P00739-1", "name": "Haptoglobin-related protein", "aln": "MSDLGAVISLLLWGRQLFALYSGNDVTDISDDRFPKPPEIANGYVEHLFRYQCKNYYRLRTEGDGVYTLNDKK-----------------------------------------------------------QWINKAVGDKLPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTG----ATLINEQWLLTTAKNLFLNHSENATAKDIAPTLTLYVGKKQ--------LVEIEKVVLHPNYH-----QVDIGLIKLKQKVLVNERVMPICLPSK-NYAEV--GRVGYVSGWGQSDNFKLTDHLKYVMLPVADQYDCITHYEGSTCPKWKAPKSPVGVQPILNEHTFCVGMSKYQEDTCYGDAGSAFAVHDLEEDTWYAAGILSFDKSCAVAEYGVYVKVTSIQHWVQKTIAEN--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G007-1", "uniprot_id": "A0AC58G007_DANRE", "id": "A0AC58G007-1", "name": "", "aln": "---MQVYYVWF----------------------TCKPNIRGIDYIYKRQNLRKIKTFIMRWLSVAVLLLGTLT----------------------------------------------------------------FLTDASPALERVG--EHVSALRSRRMVGGSLTAS--VPWQAMVYLSENILDGGFAGGALIAERWVLTAGRNLFVGKSKIQTRGQEPLIPKVYLGISKRADATASTEVAVEKVFLHPGFQNTSDWDNDLALIKLKEPVKFSKSILPIPLPETGDNLEERDGERGIVAGWGWGRLLTPAPVLKFLSLPVKS---CKGNYQARVLES----------TPNIDDKQFCTGSGRYLENVCFGDAGGAIAFLNTKTNAVYAAGILSFDKACSVEEHAVYTKISAHLPWIHSVMRGDSQDIASQRSSAIRHMFSQQL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : ** . .*: : . : : : :: . .: *. . : * * * : .. :*::** : *. .**** : ..: * .:** ::*:**:.:***:.:*: : : . .:*:* .: * :***.*** *:.*****: * ..: ::** **.. : *. * *:*** . : : **:: *** . * :*: . . * ::.: **.* :* *:.*:****.*:*. : : :: **:*******:*:* *:.**.: : *::..: : ", "identical_positions": 86, "similar_positions": 107, "identity": "19.24%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1262", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P734-1", "uniprot_id": "IC1_RAT", "id": "Q6P734-1", "name": "Plasma protease C1 inhibitor", "aln": "-----------------------------------------MASKLTPLTLLLLLLAG---------------------------------------------------DRAFSDSEVTSHSSQDPLVVQEGSRDSVPERDG-------------------------------SRSP-IEHTGQSSTWPTTSGSTKISNDTMDQVANESFIQHVQPA------------------AQLPEDSPSQSPVNSSSPPSTASAPPTQAPTEPLCP---EPLAWCSDSDRDSSEATLSEALTDFSVKLYHAFSATKKAETNMAFSPFSIASLLTQVLLGAGDSTKSNLEDILSYPKDFACVHQTLKAFS---SKGVTSVSQIFHSPDLAIRDTYVNASLSLYGSSPRVLGPD-GDANLKLINTWVAENTNHKINELLDSLPSDTRLVLLN-AVYLSAKWKKTFEQKK-MMASFLYKNSMIKVPMLSSKKYPLALFNDQTLKAKVGQLQLSHNLSFVIMVPQSP-THQLEDMEKALNPTVFKAILKKLELSKFQPTYVMMPRIKVKSSQDMLSIMEKLEFFDFTYD----LNLCGLTE-DPDLQVSSMKHETVLELTETGVEAAAASTISVA------RNLLIFEVQQPFLFLLWDQRHKFPVFMGRVYDPRA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97290-1", "uniprot_id": "IC1_MOUSE", "id": "P97290-1", "name": "Plasma protease C1 inhibitor", "aln": "-----------------------------------------MASRLTPLTLLLLLLAG---------------------------------------------------DRAFSDPEATSHSTQDPLEAQAKSRESFPERDD-------------------------------SWSP-PEPTVLPSTWPTTSVAITITNDTMGKVANESFSQHSQPA------------------AQLPTDSPGQPPLNSSSQPSTASDLPTQATTEPFCP---EPLAQCSDSDRDSSEAKLSEALTDFSVKLYHAFSATKMAKTNMAFSPFSIASLLTQVLLGAGDSTKSNLESILSYPKDFACVHQALKGFS---SKGVTSVSQIFHSPDLAIRDTYVNASQSLYGSSPRVLGPD-SAANLELINTWVAENTNHKIRKLLDSLPSDTCLVLLN-AVYLSAKWKITFEPKK-MMAPFFYKNSMIKVPMMSSVKYPVAQFDDHTLKAKVGQLQLSHNLSFVIVVPVFP-KHQLKDVEKALNPTVFKAIMKKLELSKFLPTYLTMPHIKVKSSQDMLSVMEKLEFFDFTYD----LNLCGLTE-DPDLQVSAMKHETVLELTESGVEAAAASAISFG------RSLPIFEVQRPFLFLLWDQQHRFPVFMGRVYDPRG--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05155-1", "uniprot_id": "IC1_HUMAN", "id": "P05155-1", "name": "Plasma protease C1 inhibitor", "aln": "-----------------------------------------MASRLTLLTLLLLLLAG---------------------------------------------------DRASSNPNATSSSSQDPESLQDRGEGKVATTVI-------------------------------SKMLFVEPILEVSSLPTTNSTTNSATKITANTTDEPTTQPTTEP------------------TTQPTIQPTQP---TTQLP---TDSPTQPTTGSFCP---GPVTLCSDLESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKDFTCVHQALKGFT---TKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNN-SDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLN-AIYLSAKWKTTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNL-KHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYD----LNLCGLTE-DPDLQVSAMQHQTVLELTETGVEAAAASAISVA------RTLLVFEVQQPFLFVLWDQQHKFPVFMGRVYDPRA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6R5-1", "uniprot_id": "A0ACD6B6R5_DANRE", "id": "A0ACD6B6R5-1", "name": "", "aln": "MLANICVMIYQLAERRKQQEDISAKQTDISWTSRFFQIEIRPATESSTMYRVLLLLCVGLSLSSCDITVLLYSSISLPCVPDNAPALAGSTYIWNFTAPQTEPHTLSEKGKILTLKNVNSSYSGQYKCVQEGYRDEARVRRSRTFSLQVEEPPLLQEWQVIRVEAGYDVILPCKVSFSNETISPSVVWKQVTGQGAVLLNPDKNTDVEEKKEKDKEPQRVFWDISPEEKDWAIKISQTRWKDAGMYQCVINTNQTLLVELEMEGPPPPHCEGYTDPWESCNDPDSRSSKAILQESLGDFSTSVYSRLKGSK-AKANLIFSPISIAAALSNLLLGARGKTRMHLEGALGLPLGFSCLHTELKKLRGVMKDTLKMASAIFYNPEQQLAEAFINQSKEFYEFVPQKLTND-STRNVALINKWVENKTNKKITQLIDDVDPSTTFVLLN-AVYFNGKWKTVFESTNNKEKFTMFSGETKDVKTLYSSNYILQMGYNKQLKADVGKFPLTGQNSLYILVPRTLSEESFLLMENNINRNTLEEMVSEMNQTPAQSAEVTLPAIKLTMTTQVDDLLRNMGLSDLFNN----PNLCGMFPGEPESFISDVRHRAFLSLTEKGVEAAAATSISFS------RSFSSFSALQPFVLILWSDEAAVPLFMGRIINP----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3N1-1", "uniprot_id": "SP27A_DROME", "id": "Q9V3N1-1", "name": "Serine protease inhibitor 27A", "aln": "--------------------------------------MTKMGGNLAVMLLSLFLS-------------------------------------------------------ALATGNGNS-------------------------------------------------------------------IPTTTTPQGVFETRTDKLPGGAASVPSGAG--------------------------------------------IYDDIDTFVP-------FRSDSHDPFSWHLLKTVLQNETADKNVIISPFSVKLVLALLAEAAGAGTQTQVELANTQTDIRSQNNVREFYRKTLNSFKKENQLH----ETLSVRTKLFTDSFIETQQKFTATLKHFYDSEVEALDFTNPEAAADAINAWAANITQGRLQQLVAPDNVRSSVMLLTNLIYFNGLWRRQFATTF-QGSFFRSKDDQSRAEFMEQTDY-FYYTTSEKLKAQILRLPYKGKNSLFVLLPYAL--NGIHDLVKNLENDELKSAQWAMEEVKVK---VTLPKFHFDYQQNLKETLRSLGVREIFEDSASLPGLTRGADVAGKVKVSNILQKAGINVNEKGTEAYAATVVEIENKFGGSTAIEEFNVNRPFVFFIEEESTGNILFAGKVHSPTTQN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : *:* : : .* .. : . .* . : * * : : . :. . . :: : *. ::: *. . :. . : : . :. : :* .. : : :* . * ** *. : *: :: .*: : .:**. :*:.. *: * . ... . : . .* . .. ***.: :: . : *: :::* . : : : :. :: :: : :* ::. :: . :..: . :: : .* . :* : :.: :.:.*.*.** **: :.. : *.. :**::.: .: :* *:: .* ", "identical_positions": 42, "similar_positions": 141, "identity": "6.28%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1280", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63787-1", "uniprot_id": "P85A_RAT", "id": "Q63787-1", "name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "aln": "MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEDIGWLNGYNETTGERGDFPGTYVEYIGRKRISPPTPKPRPPRPLPVAPGSSKTEADTEQPVLTLPDLAEQFAPPDVAPPLLIKLLEAIEKKGLECSTLYRTQSSSNPAELRQLLDCDPPSVDLDVFDEHVLADAFKRYLADLPNPVIPVAVYNEMMSLAQEVPSSEDYIQLLKKLIRSPNIPHQYWLTLQYLLKHFFKLSQASSKNLLNARALSEIFSHVLFRFPAASSD-NTEHLIKAVELLISAEWSERQPAPALPPKPPKPTSIANNSMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKED-NIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNDTIKIFEEQCHPQERYSKDYIEKFKREG---------------NEKEIQRIMHNHDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLG--NENTEDQYSLVDDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26450-1", "uniprot_id": "P85A_MOUSE", "id": "P26450-1", "name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "aln": "MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEDIGWLNGYNETTGERGDFPGTYVEYIGRKRISPPTPKPRPPRPLPVAPGSSKTEADTEQQALPLPDLAEQFAPPDVAPPLLIKLLEAIEKKGLECSTLYRTQSSSNPAELRQLLDCDAASVDLEMIDVHVLADAFKRYLADLPNPVIPVAVYNEMMSLAQELQSPEDCIQLLKKLIRLPNIPHQCWLTLQYLLKHFFKLSQASSKNLLNARVLSEIFSPVLFRFPAASSD-NTEHLIKAIEILISTEWNERQPAPALPPKPPKPTTVANNSMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKED-NIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREG---------------NEKEIQRIMHNHDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLG--NENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27986-1", "uniprot_id": "P85A_HUMAN", "id": "P27986-1", "name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "aln": "MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGDFPGTYVEYIGRKKISPPTPKPRPPRPLPVAPGSSKTEADVEQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDCDTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSD-NTENLIKVIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKED-NIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREG---------------NEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLG--NENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S6V7-1", "uniprot_id": "B0S6V7_DANRE", "id": "B0S6V7-1", "name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "aln": "MSAEGYQYRALYDYKKEREEDIDLHVGDILTVNKGALLALGYMEGMEERPDEVGWLPGFNETTQEKGDFPGTYVEFIGKKKISPPTPKPRPPRPLPVAPGPTRQDSDSEQSLSTLLDLTEQFAPPEVAPSMLLKLLEAIEKKGLDNPTLYRNFTAGGGLDVRQCFDSDPASVDLEQMDLQMLCDGLRRYLQDLPQPVIPPVIYNEMIRIAQEVQGTDECAQHLRLVASSTALPPQYWLTLQSLLRHFSHVCQSSAVNLLSARALAEIFSPALFRHQPTSCEPSPEAHIRIIEVLVTSEWSDSQAAPALPPKPPKPTSVANNGMNNNMALQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRTESLAQYNPKLDVKLLYPVSKHQQDQVVKED-NIEAVGKKLHEYHQQFQEKNREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFRREG---------------NEKEIQRIMVNYEKLKSRISEIVDSKRRLEEDLKKQAADYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGIKNENQDDQYSMVEDDEDLPHHDERSWKLGNINRIQAEALLRGKRDGTFLVRDSSKAGCYACSVVVDGEVKHCVINKTPTGYGFAEPYNLYNSLKELVLHYQHTSLVQHNDSLNVTLAYPVYGHQRR----------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KTZ2-1", "uniprot_id": "Q7KTZ2_DROME", "id": "Q7KTZ2-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRPQAPGSLVD---PNEDELRMAPWYWGRISREEAKSILHGKPDGSFLVRDALS-MKGEYTLTLMKDGCEKLIKICHMDRKYGFIETDLFNSVVEMINYYKENSLSMYNKTLDITLSNPIVRAREDEESQPHGDLCLLSNEFIRTCQLLQNLEQNLENKRNSFNAIREELQEKKLHQSVFGNTEKIFRNQIKLNESFMKAPADAPSTEAGGAGDGANAAASAAANANARRSLQEHKQTLLNLLDALQAKGQVLNHYMENKKKEELLLERQINALKPELQILQLRKDKYIERLKGFNLKDDDLKMILQMGFDKWQQLYETVSNQ---PHSNEALWLLKDAKRRNAEEMLKGAPSGTFLIR-ARDAGHYALSIACKNIVQHCLIYETSTGFGFAAPYNIYATLKSLVEHYANNSLEEHNDTLTTTLRWPVLYWKNNPLQVQMIQLQEEMDLEYEQAATLRPPPMMGSSAPIPTSRSREHDVVDGTGSLEAEAAPASISPSNFSTSQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* * ::.: *: *: * **** *****.:. *:...**:****** : *:*:***** *.* :***** * * **** :. *.****:**:*: :**: ** .**:.* *: : ::*: : . :: :.::: . :*: .:: :. :.:. :*:* *: ..*.:* ***.:* : :* : * : *. * : : : : :.* . :. : . : *:. :::: : :::::*::**:* *: :*:*: *. .:::..*: * :: :: *. *.:: ** :* * : . :* :** :*:* .****:* : . * ** *:. .. *:**:* :*.**:*** ***:* :**.** ** :.** :***:*..** :** :.. ", "identical_positions": 136, "similar_positions": 151, "identity": "16.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1296", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VCM3-1", "uniprot_id": "ZFY21_MOUSE", "id": "Q8VCM3-1", "name": "Zinc finger FYVE domain-containing protein 21", "aln": "MSSGVAARRDAKKLVRSPSGLRMVPEHRAFGSPFGLEEPQWVPDKECPRCMQCDAKFDFITRKHHCRRCGKCFCDRCCSQKVPLRRMCFVDPVRQCADCALVSHREAEFYDKQLKVLLSGATFLVTFGDSEKPETMVCRLSNNQRCLVLDGDSHREIEIAHVCTVQILTEGFTPG-----------------AGSTRATGMLLQYTVPGAEAAAQLRLMAGEDASGSKRQAAAWLAAMHKATKLLYESRDQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQ24-1", "uniprot_id": "ZFY21_HUMAN", "id": "Q9BQ24-1", "name": "Zinc finger FYVE domain-containing protein 21", "aln": "MSSEVSARRDAKKLVRSPSGLRMVPEHRAFGSPFGLEEPQWVPDKECRRCMQCDAKFDFLTRKHHCRRCGKCFCDRCCSQKVPLRRMCFVDPVRQCAECALVSLKEAEFYDKQLKVLLSGATFLVTFGNSEKPETMTCRLSNNQRYLFLDGDSHYEIEIVHISTVQILTEGFPPG-----------------GGNARATGMFLQYTVPGTEGVTQLKLTVVEDVTVGRRQAVAWLVAMHKAAKLLYESRDQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A6I2-1", "uniprot_id": "B8A6I2_DANRE", "id": "B8A6I2-1", "name": "", "aln": "----MSAVPDGKKLVRSPSGLRMVPENGAFNSPFTLDEPQWVPDKECPRCMQCDTKFDFITRKHHCRRCGRCFCDKCCSQKVALPRMCFVDPVRQCAECSLISQKEVEFYDKQLKVLTAGGTFVVKVGSSEKSETMVCRLSNNHRYLFLDGNSHFEVELSRISSMQVLTEGSTPGEKDICSYTSLLDNQISEGGTLRASGMVLQYKPPGSLDLQQLNMDTADD----KRIASAWLAAMHKAAKLLYESKDQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* *.***************: **.*** *:********** ******:****:**********:****:******.* ************:*:*:* :*.********** :*.**:*..*.***.***.******:* *.***:** *:*: ::.::*:**** .** .*. **:**.***. **: **.: . :* :* * ***.*****:******:**", "identical_positions": 154, "similar_positions": 50, "identity": "61.35%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-13", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K6R0-1", "uniprot_id": "A0A0G2K6R0_RAT", "id": "A0A0G2K6R0-1", "name": "", "aln": "MHTNEGEVEEESSSQVEQEDFVMEGHGKTPPPGEESKQEKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPSPPVN----------------GGNNAKRVAVPNGQP----PSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGG--AGPPPCTAPGANPNN-AQVTGALLQSESGTAPESTLGGAAASNYANSTWGPGASSNNGASPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENT----TDNNSASNPGS--------EKSALPGSTTSNKGK--GSQCQSASSG--NECNLG--VWKS---DPKAKSVQSPNSTSDSNNGLGTWRSTSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTCRKGVLEAEGSSSSAQVSTVGQASREQQSKMENAGVNFVVSGREQAQIHNTDG--PKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGADTVSGQSNSGNNG----NNGKDREDSWKGASVPKPTGSQSDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSAGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPAHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSN-----QMKSGWGELSASTEWKDPKSTGG--WNDYKNNNSSNWGGGRA----DEKTPSSWNE-----SSCKDQ-----GWGGGRQPN---QGWTS----------------------------GKNGWG--EEVDQVKNNNWESS--------ANKPVSGWGE-------GGQSEIGTWGNGGNTNLASKGGWEDCKRSPAWNETG------------------RQPNSWNK-----QHQQQQQQ--PPPPQPEASGSWGGPPPPPQG-NVRPSNSNWSSGPQPATP----KDDEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKN-----------SQGGPAPREPNLPTPMTG-----------------KSASVWS---KSTPPAPDNGTSAWGEPNESSPGWGEMDDAGASATGWGNTPASAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEDD-GGVWNTAGSQGSTSSHNSASWGQGGKKQMKCSIKG-NNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSV----DKKFDVDKRTMNLGDFNDIMRKDRPG------FRPPNSKDLGTTDSGPYFEKLTLPFSNQDGCLGDEAPCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGLFGNSTAQSRGLHTP-VQPLSSSPGLRAQVPPQFISPQVSASMLKQFPNSGLNPGLFNVGPQLSPQQIAMLS-QLPQIPQFQLACQLLLQQQ---QQQQ-LLQNQRKISQAVRQQQE-QQLARMVSALQQQQQQQQQQQQQQQQQQQQQRQPSMKHSPSHPVGPKPHLDNMVPN-----TLNVGLPDLPTKGPIPGYGSGFSSGGMDYG-MVGGKEAGTES--RFKQWTSMMEG-LPSVATQEATMHKNGAIVAPGKTRGGSPYNQFDIIPG-DTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPK--PASPWSSTAPRSVRGWG----TQDSRIASA-STWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATEDEVSRFLAQAQPPTP------------------------------AATPSAPATGWQSLETSQNQADPVG--------------------PALNLFGGSTG-----------LGQWSSSAGGSS------GADLAGTSLWG--PPNYS-SSLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BKI2-1", "uniprot_id": "TNR6B_MOUSE", "id": "Q8BKI2-1", "name": "Trinucleotide repeat-containing gene 6B protein", "aln": "MQTNEGEVEEESSSQVEQEDFVMEGHGKTPPPGEESKQEKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPSPPVN----------------GGNNAKRVAVPNGQP----PSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGG--AGPPPCTAPGANPNNNAQVTGALLQSESGTAPESTLGGAAASNYANSTWGPGASSNSGASPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENT----TDNNSASNPGS--------EKSSLPGSTTSNKGK--GSQCQAASSG--NECNLG--VWKS---DPKAKSVQPPNSTSDSNNGLGNWRSTSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETESSSSSAQVSTVGQASREQQSKMENAGVNFVVSGREQAQIHNTDG--PKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNG----NNGKDREDSWKGASVPKPTGSKSDSWDNNNRSTGGSWNFGPQDNNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSAGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSN-----QMKSGWGELSASTEWKDPKSTGG--WNDYKNNNSSNWGGGRA----DEKTPSSWNE-----SSCKDQ-----GWGGGRQPN---QGWTS----------------------------GKNGWG--EEVDQVKNNNWESS--------ANKPVSGWGE-------GGQNEIGTWGNGGNTNLASKGGWEDCKRSPAWNETG------------------RQPNSWNK-----QHQQQQQ---PPPPQPEASGSWGGPPPPPQG-NVRPSNSNWSSGPQPTTP----KDDEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKN-----------SQGGPAPREPNLPTPMTG-----------------KSASVWS---KSTPPAPDNGTSAWGEPNESSPGWGEMDDAGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEDD-GGVWNTAGSQGSTSSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSV----DKKFDVDKRTMNLGDFNDIMRKDRPG------FRPPNSKDLGTTDSGPYFEK---------------------------------------------------------GGSHGLFGNSTAQSRGLHTP-VQPLSSSPGLRAQVPPQFISPQVSASMLKQFPNSGLNPGLFNVGPQLSPQQIAMLS-QLPQIPQFQLACQLLLQQQ---QQQQQLLQNQRKISQAVRQQQE-QQLARMVSALQQQQQQQQQQQ----------RQPSMKHSPSHPVGPKPHLDNMVPN-----ALNVGLPDLPTKGPIPGYGSGFSSGGMDYG-MVGGKEAGTES--RFKQWTSMMEG-LPSVATQEATMHKNGAIVAPGKTRGGSPYNQFDIIPG-DTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTTTSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLTRPPPGLTNPK--PASPWSSTAPRSVRGWG----TQDSRIASA-STWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATEDEVSRFLAQAQPPTP------------------------------AATPSAPATGWQSLETSQNQADPVG--------------------PALNLFGGSTG-----------LGQWSSSAGGSS------GADLAGTSLWG--PPNYS-SSLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPQ9-3", "uniprot_id": "TNR6B_HUMAN", "id": "Q9UPQ9-3", "name": "Trinucleotide repeat-containing gene 6B protein", "aln": "------------------------------------MREKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPSPPVN----------------GGNNAKRVAVPNGQP----PSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGG--AGPPPCTAPGANPNN-AQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENT----TDNNSASNPGS--------EKSTLPGSTTSNKGK--GSQCQSASSG--NECNLG--VWKS---DPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDG--PKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNG----NNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSN-----QMKSGWGELSASTEWKDPKNTGG--WNDYKNNNSSNWGGGRP----DEKTPSSWNE-----NPSKDQ-----GWGGGRQPN---QGWSS----------------------------GKNGWG--EEVDQTKNSNWESS--------ASKPVSGWGE-------GGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETG------------------RQPNSWNK-----QHQQQQPPQQPPPPQPEASGSWGGPPPPPPG-NVRPSNSSWSSGPQPATP----KDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKN-----------SQGGPAPREPNLPTPMTS-----------------KSASVWS---KSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEED-GGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSG------FRPPNSKDMGTTDSGPYFEKLTLPFSNQDGCLGDEAPCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGLFGNSTAQSRGLHTP-VQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLS-QLPQIPQFQLACQLLLQQQ---QQQQ-LLQNQRKISQAVRQQQE-QQLARMVSALQQQQQQQQ-------------RQPGMKHSPSHPVGPKPHLDNMVPN-----ALNVGLPDLQTKGPIPGYGSGFSSGGMDYG-MVGGKEAGTES--RFKQWTSMMEG-LPSVATQEANMHKNGAIVAPGKTRGGSPYNQFDIIPG-DTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPK--PSSPWSSTAPRSVRGWG----TQDSRLASA-STWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTP------------------------------AATPSAPAAGWQSLETGQNQSDPVG--------------------PALNLFGGSTG-----------LGQWSSSAGGSS------GADLAGASLWG--PPNYS-SSLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U183-1", "uniprot_id": "A0AB32U183_DANRE", "id": "A0AB32U183-1", "name": "", "aln": "------------------------------------------------MEDKKRKKEDKRKRETSQKVAEQKNKVPELTKPPSAQSPAAPNSASPSPGPVPSSTPSAATPAAGTLPQGGNNAKRPAVANGQPSPSTPNSQRYMPREVPPRFRCQQDHKVLLKRGQPP-LSSMLLGGGNSGGDSPNETVASASDPSQGPVGPAAPSLPHTSSASSIAASSSSNYANSMWGTSSGSHPLSQGR-----EKVIVDRSDLEEWPSIAAGDGSKSGDAAGTGGTDSGAILNCNASWGERHLQQQAKVVGGGNGRKGVNSGSPSPPTSSGSPNECMQSGSVWASSSHELIGGNAVAAGSLPPISKAAPLPGSSDSSFGVSCGIPGANFTPNANPSAWPALVQEG---AGTVATEGGSSSLQSSSLSASNPLSVNQASHQHQLHQMQSRDREPSCGEWGGTALEPGAGPKNTGVTEGADMDSGSTGGGAGSASSSSSTSSSLWRTQPFPANFKTGASRTESWDDGAGGSSLSAEGGKAWGYPGQDDRGDLTGAGAWG-TGSGGQTPGVSQGAWGGDHLLGGEWGASS--GVGGVSDQGGKDGSSSNSSSSGGSVSIPTTTSSTPSTMTRAWDNQK---AVGDVGAGDLSEWGGQGSRGGEGTSSSSGGGNSRSG--NQRHGHHRTHKP--PDPEVALQDLLSRSDLDPRVLSNTGWGQTQIRQNVAWDLEDGGRAKAPGGANSLSIGASAHAQPYSGPSGSTTTDPSSPSLLQAASLNANLNSNSILGPPAVSSGEGWDNSSSNSSSLHTRGPPPSGVNIQNPSVSQSGGGGGSSAGGQGMPSGGWGGTASSEGQVKGWESEGHEWRERRAGGSSGGWGDFQTQGTPSTGGSGWGDSQEEKGTRSSGWKEMGRVDAGSWGPRGTSDWGEKESKSCSGGWDGKGGGGTSGDSEVGTWGNWDDGTPGGTWGGVGGDMGGKSHQGWGGKMHPSQMPNSQSASQKGPAQQQQQPQSQPQQCQSVDTGAMQGGWGRPAGPSVQSQSSGWNSGPIPQISNGPGETSEPSGWEEPSPQSISRKMEIDDGTSAWGDPSNYNYKSVNLWDKNNAPSGQAQSVSPQQGPPPLQQPPPGRMPTGLGNRDMNIAHSASKGPGIASGWGGRGSPSSPCVDNGTSAWGKPTEAPTGW---DDSGKASS-WGDPSS---NPVKSGSKSMQEGWVEGEGSVSASRNPSWEEEDESGGVWNSAGSQGSSSSYNSGGWG--AKKGNKGSLKG-AGDSWMNPMSRQFSNMGILGEDAGGRS--LDLAPGPPQDKKMEGEKRGMGLNEYNGEMRKGGRGGGAGAVFRSPGSKEVGACEPGPYYDK----------------------------------------------------------ASGQLFSSGGGMAQSRHQPGVPPIN--PSVRAQVPHQFLSPQVPGSVLKQMPPPSGGVGGGIFPPQLSPQHIAMLSSIYPPHLQFQLACQLLLQQQPQQQQQQQLLQNQRKFPPNIRQQADPQQLARIMAVLQQQRQQQQHVGG---------TGGSSKLSPSHLGGSGPKMPMSDPLSHPGLAGSVADIHQKTQGAYSGFGPGMSLSGLELGPMVGGPAGLKDSGGQQSRFKWMMEGHSPAPSPPDSTLHKNGPIAAPLKMRGGSPYSQYEMLGGGEGLGVPPQGPSDHWHRS---PGNKMGTKTGTSSWPPEFQPGVPWKGRPNVDTDSDPYMTPGSMLG-SSMSSLNDTEHQLLRDNTE-SNPSLNTLLPSPGAWPYSASESPLTNAHN-PAKYTDYKPSWPPEPIGHN------KPWK---TNRNNSHLPRPPPGLTHQKQPSVSPWTSGGPRVGRGWGGSGGSQENRFGPG-SAWSDGGASKGSCWLVLSNLTPQIDGSTLRTICMQHGPLLTFHLGLTQGSALIRYSSRQEAAKAQSALHMCVLGNTTILAEFVSEEEVARYFAHSQAGAAGSGSGGSGAGGVAVSGPAG----------VAGSSGAGAVGTISAASGDRERAAVGSLTAGGSSNSGGTGPSGSTWQSLDGTGSSSDPASAQGAGLSIFAQWSSNGAGGSNA---AGVDPGRAGLWGGMTPGYTGSSLWASPAMEDRHQMNSPAALLPGDLLGGGADSI------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8SY33-1", "uniprot_id": "GAWKY_DROME", "id": "Q8SY33-1", "name": "Protein Gawky", "aln": "------------------------------------------------MREALFSQDGWGCQHVNQDTNWEVPSSPEPANKDAPGPPMWKPSIN-----------------------NGTDLWESNLRNGGQ-------------------------------------------------------------------------------------PAAQQVPKPSWGHTPSSNLG------------------------GTWGEDDDGADSS-------------------------SVWTGGAVSNAGS--GAAVGVNQAG------------------------VNVGPGGVVSSGGPQWG--QGVVGVGLGSTGGNGSSNITGSSG---VATGSSGNSSNAGNGWGDPREIRPLGVGGSMDIRNVEHRGGNGSGATS-----------------SDPRDIRMIDPRD----PIRGDPRGISGRLNGTSEMWGHHPQMSHNQLQGINKMVGQSVATASTSVGTSG----------------------SGIGPGGPGPSTVSGNIPTQWGP--AQPVSVGVSGPKDMSKQISGWEEPSPPPQRRSIPNYDDG-----TSLWGQQTRVPAASGHWKDMTDSIGRSSHLMRGQSQTGGIG----------IAGVGNSNVPVGANPSNPISSVVG-----PQARIPSVGGVQHKPDGGAMWVHSGNVGGRNNVAAVTTWGDDTHSVNVGAPSSGSVSSNN------------------------------WVDDKSNSTLAQN--------------SWSDP----APVG------------------------------------------------------VSWG----NKQSKPP-------------SNSASSGWST-------------------------AAGVVDGVDLGSEWNTHG------------------------------------------------------GIIGKSQQ---QQKLAGLNVGMVNVIN------------AEIIKQSKQYRILVENGFKKEDVERALVIANMNIEEAA-----------------------------------------------------------------------------------------------------DMLRANSSLSMDGWRRHDESLG-----SYADHNS----STSSGGFAGRYPVNS------------------GQPSMSFPHNNLMNNMGGTAVTGGNNN-------------------TNMTALQVQKYLNQGQHG-------VAVGPQAVGNSS-----------------------------------------------------------------AVSVGFGQNTSNAAVAGAASVNIAANTNNQPSGQQIRMLGQQIQLAIHSGFISS------QILTQPLTQTTLNLLNQLLSNIKHLQAAQQSLTRGG-----------NVNPMAVNVAISKYKQQIQNLQNQINAQQAVYVK-------------QQNMQPTSQQQQPQQQQLPSVHLS-------NSGNDYLRGHDAINNLQSNFSELNINKPSGYQGASNQQSRLNQWKLPVLDKEINSDSTEFSRAPGATKQNLTANTSNINSLGLQNDSTWSTGRSIGDGWPDPSSDNENKDWSVAQPTSAATAYTDLVQEFEPGKPWKGSQIKSIEDDPSITPGSVARSPLSINSTPKDADIFANTGKNSPTDLPPLSLSSSTWSFNPNQNYPSHSWSDNSQQCTATSELWTSPLNKS-------------SSRG------PPPGLTANSNKSANSNASTPTTITGGANGWLQPRSGGVQTTNTNWTGGNTTWGSSWLLLKNLTAQIDGPTLRTLCMQHGPLVSFHPYLNQGIALCKYTTREEANKAQMALNNCVLANTTIFAESPSENEVQSIMQHLPQTPSSTSSSGTSGGNVGGVGTSANNANSGSAACLSGNNSGNGNGSASGAGSGNNGNSSCNNSAAGGGSSSNNTITTVANSNLVGSSGSVSNSSGVTANSSTVSVVSCTASGNSINGAGTANSSGSKSSANNLASGQSSASNLTNSTNSTWRQTSQNQALQSQSRPSGREADFDYISLVYSIVDD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.: .::. :...*.. : . ** :: . .. . .*.: . : ** .::.: .:. ** ..*: : : ....: : : *. .. * *: .:* .. ... .. :. * .* ..* . *: * * . :. ... : .:. . . : .: :.. : : : . . . * . .*. : : . . . . . ..: . .* :* . . : . * * .. . . . .:.: . . * *.:*. . * .. . * . .: * .: . :. ::. *:. : * : :. . :.. . : .. ..: :. . * : ..*.: .. . .** . : . *.*. : * :. . *. * * . : . :. . * * ** . :: :::* . . .:*: : : ::..*. :** . : .: *: :.:. .::*. .. . ** * * . :.*** . .. . * : : :.:. * . ..: :* . . *... . : . * . : :::. *: :: . : . . *: : :*. . ::* * * * : * . :. : . **: .: :: *: . : :..: :: . . :.. . ..:* .:: * . : . * : : .: :.* . .. .: . :* ... : .: :. :. **:** **** . :.** :****: . .: ::: :. * ..* . *..:*.:...:. :: . :: .. ..*:.:. :.*. ****** . . .. :* . * . .:.. . . : *:.*.: * **:* ***.****.****:*******::** *.** ** :*::::** *** **: ***.****:** :::** : : .. :.. .. . * * . .: . * ..* . .. *....*.* . . . . . ... : :* .: . :: .. .* . . .* .: ", "identical_positions": 171, "similar_positions": 448, "identity": "7.87%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1312", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P34810-1", "uniprot_id": "CD68_HUMAN", "id": "P34810-1", "name": "Macrosialin", "aln": "MRLAVLFSGALLGLLAAQGTGNDCPHKKSATLLPSFTVTPTVTESTGTTSHRTTKSHKTTTHRTT-TTGTTSHGPTTATHNPTTTSHGNVTVHPTSNSTATSQGPSTATHSPATTSHGNATVHPTSNSTATSPGFTSSAHPEPPPPSPSPSPTSKETIGDYTWTNGSQPCVHLQAQIQIRVMYTTQGGGEAWGISVLNPNKTKVQGSCEGAHPHLLLSFPYGHLSFGFMQDLQQKVVYLSYMAVEYNVSFP-HAAQWTFSAQNASLRDLQAPLGQSFSCSNSSIILSPAVHLDLLSLRLQAAQLPHTGVFGQSFSCPSDRS-ILLPLIIGLILLGLLALVLIAFCIIR-RRPSAYQAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5I3-1", "uniprot_id": "A0ACD6B5I3_DANRE", "id": "A0ACD6B5I3-1", "name": "", "aln": "-MHVVSFQANKCSVRQTFNTTQATDAALQLTIQRSFCVRCIEKQTKMKHGLLMIAICIAAAALTSGQYSSTLQGGPTSKPDPTTT-----TTAPPPTTTTTTHAPNTTTHAPNTTTHAPNTTTHAPNTTTHAP-NTTTHAPNTTTPIPAPTPPANLTVGKYNSSQDGKLCILADFAIGIRVNTSEVN-----DTFIVQPSKTTSSGGCSEKTANINLLFGEGSVILKFVNDDTAQKIYVQLVEVDLTYAFNTKVGSKNYSGKNDSLQLFASVPGHYYSCSSQTVYMGNGLSLDLTHNKIQAFNFKNN-EFGTPDVCKADQPDYRVPIAVGIILIILIVIVVIAYLISRKRRTDGYQSL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* *.. .: : .* : . *: ** * .::. . . ::: *: .:* :* .*:. :**** *. *...:*:*::.*.*:**:* **:*. *. :.*:*: :* *:: *:...* *:*:*.:: *:*.*. ::..: *: : * *** : . . :::*.**. .*.*. .:: * * * : : *::* : :*:. : *: . :* :... .:*.:* **: : : *: :***..:: :. .: *** ::** :: :. ** . * :*:. :*: :*:**: *:.:*:**: * * **...**:*", "identical_positions": 90, "similar_positions": 139, "identity": "25.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1325", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C025-1", "uniprot_id": "CHPT1_MOUSE", "id": "Q8C025-1", "name": "Cholinephosphotransferase 1", "aln": "MAAGAGARPAPRWVKALGEPLSAAQLRRLEEHRYTAVGESLFEP-PLQLYWTWLLQWIPLWMAPNTITLIGLAINLVTTLVLIFYCPTVTEEAPYWTYLLCALGLFIYQSLDAIDGKQARRTNSCSPLGELFDHGCDSLSTVFMAIGASIAVRLGTHPDWLFFCSFVGMFMFYCAHWQTYVSGVLRFGRVD--VTEIQVALVIVFMLSTFGGATMWDYTIPILEIKLKIVPVLGVVGGLIFSCSNYFHVILHGG------VGKNGSTIAGTSVLSPGLHIGLIIILAIMIYKKSATNMFEKHPCLY----TLMFGCVFAKVAQKLVIAHMTKSELYLQDTVFIGPGLLFLDQYFNNFIDEY-------VVLWIAMVISSFDMMIYFTSLCLQISRHLHLNIFKTSCQQAPEQVYKHID----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66H21-1", "uniprot_id": "CHPT1_RAT", "id": "Q66H21-1", "name": "Cholinephosphotransferase 1", "aln": "MAAGAGARPAPRWVKALGEPLSAAQLRRLEDHRYSAAGESLFEP-PLQLFWTWLLQWIPLWIAPNTITLFGLAINLFTTLVLIFYCPTVTEEAPYWTYLLCALGLFIYQSLDAIDGKQARRTNSCSPLGELFDHGCDSLSTVFMAIGASIAVRLGTHPDWLFFCSFVGMFMFYCAHWQTYVSGVLRFGRVD--VTEIQVALVIVFLLSTFGGAMMWDYTIPILEIKLKILPVLGVVGGLIFSCSNYFHVILHGG------VGKNGSTIAGTSVLSPGLHIGLIIILAIMIYKKSATNVFEKHPCLY----TLMFGCVFAKVAQKLVIAHMTKSELYLQDTVFIGPGLLFLDQYFNNFIDEY-------VVLWIAMVITSFDMMIYFSSLCLQISRHLHLSIFKTSYQQAPEQVHKHID----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WUD6-1", "uniprot_id": "CHPT1_HUMAN", "id": "Q8WUD6-1", "name": "Cholinephosphotransferase 1", "aln": "MAAGAGAGSAPRWLRALSEPLSAAQLRRLEEHRYSAAGVSLLEP-PLQLYWTWLLQWIPLWMAPNSITLLGLAVNVVTTLVLISYCPTATEEAPYWTYLLCALGLFIYQSLDAIDGKQARRTNSCSPLGELFDHGCDSLSTVFMAVGASIAARLGTYPDWFFFCSFIGMFVFYCAHWQTYVSGMLRFGKVD--VTEIQIALVIVFVLSAFGGATMWDYTIPILEIKLKILPVLGFLGGVIFSCSNYFHVILHGG------VGKNGSTIAGTSVLSPGLHIGLIIILAIMIYKKSATDVFEKHPCLY----ILMFGCVFAKVSQKLVVAHMTKSELYLQDTVFLGPGLLFLDQYFNNFIDEY-------VVLWMAMVISSFDMVIYFSALCLQISRHLHLNIFKTACHQAPEQVQVLSSKSHQNNMD--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZW02-1", "uniprot_id": "CHPT1_DANRE", "id": "Q7ZW02-1", "name": "Cholinephosphotransferase 1", "aln": "MPQCECP-----------EPLSAVQLKRLEEHKYSAAGRSLFEP-PCQIYWNWLVQQIPTWVAPNTLTTIGLVINVITTVILVYYSPTATEEVPGWAFFLSALGLFIYQSLDAIDGKQARRTNSSSALGELFDHGCDAVSTVFVAVGTCICCGIGAYPNWMFFCGFVGMFMFFCAHWQTYVSGTLRFGLVD--VTEVQIAIIIMYLLTAFTGVSFWEMRVPVLGVNLQTFPILGIIGGFLYSTYNYFFVIMNGG------VGKNGSTVADTSVLTPGLHIGLILTLAFIIFKKSSSHLFEHHPCLY----VLTFGMVIAKISNKLVVAHMTKSELHLQDTAFIGPGLLFLNQYFNSYIDEH-------IVLWIAMVLSLVDLVRYCTAVCLQIASHLRIRVFSIS-----PQGHAHKD----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K7Y4-1", "uniprot_id": "A0A0B4K7Y4_DROME", "id": "A0A0B4K7Y4-1", "name": "diacylglycerol cholinephosphotransferase", "aln": "MALLAYR---------DKHILSAQQLRKLSEHKYSCFSVSLLDP-LLQPWWNWLVAQTPLWLAPNLITIVGLILNVVTTLILICYSPNGVEAPPRWTCLLCALGLFIYQSLDSIDGKQARRTNTSSPLGELFDHGCDSISTVFVALSACISCQLGHYPNWLFFQCFCAIALFYCAHWQTYVSGTMRFGRID--VTEAQFSIIAIHLVSAALGPEIWLTKLPHFNCESRFLPIYVACGVDLILALRYTKCILTEG------CGKNGSSVAGTSVLSPSIPLTLVVLPALMIAQKSPQNLFTEHASVY----IMAFGMVAAKVTNKLVIAHMTKAEMEYLDWSLLGPSLLFLNQYFNCIVPEI-------WLLWFTLIWGTQDLLRYCAQVCLEICQHLRIDLFRIPYTPKGATPHPATASVSSQSNFGSSADKNGGSAHRKSKSKPH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17898-1", "uniprot_id": "CPT1_YEAST", "id": "P17898-1", "name": "Cholinephosphotransferase 1", "aln": "----------------MGFFIPQSSLGNLKLYKYQSDDRSFLSNHVLRPFWRKFATIFPLWMAPNLVTLLGFCFIIFNVLTTLYYDPYFDQESPRWTYFSYAIGLFLYQTFDACDGMHARRTGQQGPLGELFDHCIDSINTTLSMIPVCSMTGMG-YTYMTIFSQFAILCSFYLSTWEEYHTHKLYLAEFCGPVEGIIVLCISFIAVGIYGPQTIWHTKVAQFSWQDFVFDVETVHLMYAFCTGALIFNIVTAHTNVVRYYESQSTKSATPSKTAENISKAVNGLLPFFAYFSSIFTLVLIQPSFISLALILSIGFSVAFVVGRMIIAHLTMQPFPMVNFPFLIPTIQLVLYAFMVYVLDYQKGSIVSALVWMGLGLTLAIHGMFINDIIYDITTFLDIYALSIKHPKEI------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .* .*. ::* . . *::. : :* : * *:*** :* .*: . :...: : * * : * *: : *:***:**::*: ** :****. ..******* *::.*.: : .. :* :. :* * : *: : *: * : : :. . * . : . : :* :. : : . : *: .:.:. * .* : .: : .:: .* :. :... : :* * : ::::**:* : : :: * : :: * : : ::*: : : : :* .* : : ", "identical_positions": 60, "similar_positions": 118, "identity": "13.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1332", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIC2-1", "uniprot_id": "ECSIT_RAT", "id": "Q5XIC2-1", "name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "aln": "MSWVQVNL---LARGLSRGWGS-ICRTVLSGTPFAQPS------LQA-RGLHCSAVTHKDDVW---LVPRPSEPQKKPIKVPAMHEDLFRPSGNGEQDKASFLNAVRSFGEHNVRKRGHVDFIYLALRKMPEFGVERDLSVYNLLLDVFPKEVFRPRNAIQRIFVHYPRQQECGVAVLEQMERHGVMPNTETEFLLIQVFGHKSYPMLKFLRMKLWFTRFKNINPYPVPRDLPQDPLDLAKLGLRHMEP-DLSAKVTVYQMSLPSESTGIEDPTQPHIVGIQSPDQQAALARHNPSRPVFVEGPFPLWLRNKCVYYHILRADLPPPEEETVEEIP-----EEWNLYYPMQLDLEYSRSAWDNYEFDMDEVTEGPVFAMCMTGAHDQATLVKWIQGLQET-NPTLAQIPVVFRLARSTGELLATTRLEGQSPPHSPPKGPEEDDEAIQAQQRQGQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZH6-1", "uniprot_id": "ECSIT_MOUSE", "id": "Q9QZH6-1", "name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "aln": "MSWVQVNL---LVRSLSRGWGG-LCRPALSGTPFAQVS------LQALRGLHCSAATHKDEPW---LVPRPPEPQRKPIKVPAMHEDLFKPSGNRERDKASFLNAVRSFGAHNVRKRGHVDFIYLALRKMPEFGVERDLSVYNLLLDVFPKEVFRPRNVIQRIFVHYPRQQECGVAVLEQMERHGVMPSAETEFLLIQIFGRKSYPMLKFLRMKLWFTRFKNINPYPVPRDLPQDPLDLAKLGLRHMEP-DLSAKVTVYQMSLPSDSTGMEDPTQPHIVGIQSPDQQAALARHNPSRPVFVEGPFPLWLRNKCVYYHILRADLPPPEEEKVEEIP-----EEWELYYPQKLDLEYSRSGWDDYEFDVDEVTEGPVFAMCMAGAHDQATLIKWIQGLQET-NPTLAQIPVVFRLARSTGELLTTSRLEGQSPPHSPPKGPEEDDETIQAEQQQGQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQ95-1", "uniprot_id": "ECSIT_HUMAN", "id": "Q9BQ95-1", "name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "aln": "MSWVQATL---LARGLCRAWGG-TCGAALTGTSISQVP------RRLPRGLHCSAAAHSSEQS---LVPSPPEPRQRPTKALVPFEDLFGQAPGGERDKASFLQTVQKFAEHSVRKRGHIDFIYLALRKMREYGVERDLAVYNQLLNIFPKEVFRPRNIIQRIFVHYPRQQECGIAVLEQMENHGVMPNKETEFLLIQIFGRKSYPMLKLVRLKLWFPRFMNVNPFPVPRDLPQDPVELAMFGLRHMEP-DLSARVTIYQVPLPKDSTGAADPPQPHIVGIQSPDQQAALARHNPARPVFVEGPFSLWLRNKCVYYHILRADLLPPEEREVEETP-----EEWNLYYPMQLDLEYVRSGWDNYEFDINEVEEGPVFAMCMAGAHDQATMAKWIQGLQET-NPTLAQIPVVFRLAGSTRELQTSS--AGLEEPPLPEDHQEEDD-NLQRQQ-QGQS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08CK1-1", "uniprot_id": "ECSIT_DANRE", "id": "Q08CK1-1", "name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "aln": "MSASHHLLRLQCVRCVSHFLGTPVRQVILPGRAHLQTPGSQHIYVQLLRPFHRSAVCSTDRQNRTDIEKLVEDETHHKDKTLVTHDDIFDRAAGDSKTKVEFNRVVDVFKSKDIRRRGHVEFIYAALKKMPEFGVECDVTVYNKLLDVFPKEVFVPQNFIQRMFNHYPRQQECGVQVLEQMENYGVMPNIETKVLLVQIFGEKSHPIRKFQRIMYWFPKFKHTNPYPVPHVLPSDPVDLAQFSLTRIAA-DLDAKITIYQYPSTDITETGEEITRPHIVGIQSPDQRSLLAKHNPCKPVFVEGPYPLWLRQKCVHYYLLRADPIPPEEKVEEEIDPEMICPEQSLFFPQRVELDLKVDMGDDHSFNVDEVEEGAVYAMCMAGQGDQATLSQWISGLQET-CPILGQIPTVFRLESGPRELQTSTDDHQRPEQEAETDQIIEDDEEPRHSRGVKQ-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9U6M0-1", "uniprot_id": "ECSIT_DROME", "id": "Q9U6M0-1", "name": "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial", "aln": "------MLR--RAQCLLRLHGN-------GGHSLVS----------RFRNYATDEGNPKQNPN------PNPRAQKPGTKNLPALRNPFAAAQDRTKN--SYLTMVEIFQERDVHRRNHVEFIYAALKNMADFGVERDLEVYKALINVMPKGKFIPTNMFQAEFMHYPKQQQCIIDLLEQMEDCGVMPDHEMEAMLLNVFGRQGHPLRKYWRMMYWMPKFKNLSPWPLPDPVPDDTLEMAKLALERMCTVDLRSKITVFET-----SELKDAIDDTWIVSGMSPEQEKLLREHSRQKALYIEGPFHIWLRNRRINYFTLRADADSEFLSELDERQLDE-DDVSHIEVPFFGRAPPRRHNQLGKLRSVHQQDDGTIMAICATGTSTKDSLLSWIRLLEANGNPSIGEVPVLFRFTSEVP--AKAEEIEGGASVPATSDNSSQDEHISSRQK-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: : : * * . . * . .. : * : * : . : .: * * :.:::*.*::*** **::* ::*** *: **: *::::** * * * :* * ***:**:* : :***** ****. * : :*:::**.:.:*: * *: *:.:* : .*:*:* :*.*.:::* :.* :: . ** :::*::: : . **. **:*. * .*. :.:::***: :***:: : *. **** . :* : * . .:.: :*.: *:* :* : :: .** *: . * :.::*.:**: : . :*: .: ", "identical_positions": 96, "similar_positions": 125, "identity": "21.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1342", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q03626-1", "uniprot_id": "MUG1_RAT", "id": "Q03626-1", "name": "Murinoglobulin-1", "aln": "MKKNREAQLCLFSALLAFLPFASLLNGNSKYMVLVPSQLYTETPEKICLHLYHLNETVTVTASLISQRGTRKLFDELVVDKDLFHCLSFTIPR-LPSSEEEESLDINIEGAKHKFSERRVVLVKNKESVVFVQTDKPVYKPGQSVKFRVVSMDKNLHPLNELFPLAYIEDPKMNRIMQWQDIKTENGLKQLSFSLSAEPIQGPYKIVILKQSGVKEEHSFTVMEFVLPRFGVDVKVPNAISVYDEIINVTACAIYTYGKPVPGHVKISLCHGNP------SFSSETKSACKEEDSELDNNGCSTQEVNITEFQLKENYLKMHQAFHVNATVTEEGTGSEFSGSGRIEVERTRNKFLFLKADSHFRHGIPFFVKIRLVDIKGDPIPNEQVFIKAQEAG---YTNATTTDQHGLAKFSIDTSSISGYSLNIKVY--------HKEESSCIHSSCTAERHAEEHHTAYAVYSLSKSYIYLDTEAG-VLPCNQIHTVQAHFILKGQVLGVLPQIVFHYLVMAQGSILQTGNHTHQVEPGVSQVQGNFALEIPVEFSMVPVAKMLIYTILPDGEVIADSVTFQVEKCLRNKVHLSFSPSQSLPASQTHMRVTASPQSLCGLRAVDQSVLLLKPEAELSPSLIYDLPGMQDSNFIPSSYHPFEDE--YDCLMYQPRDTEELTYSVPYGREK----------DVYRYVRDMGLTAFTNLKIKHPTYC-YEMNMVVLSAPAVESELSPRGGEFEMMPLGVNKSPLPKEPPRKDPPPKDPVIETIRNYFPETWIWDLVTVNSSGVTEVEMTVPDTITEWKAGALCLSNDTGLGLSSVATLQAFQPFFVELTMPYSVIRGEAFMLKATVMNYLPTSLPMAVQLEASPDFTAVP-VGNDQDSYCLGANGRHTSSWLVTPKSLGNVNFSVSVEAQQSPELCGSQVATVPETGRKDTVVKVLIVEPEGIKKEHTFSSLLCASDAELSETLSLLLPPTVVKDSARAHFSVMGDILSSAIKNTQNLIQMPYGCGEQNMVLFAPNIYVLKYLNETQQLTEKIKSKALGYLRAGYQRELNYKHKDGSYSAFGDHN-GQGQGNTWLTAFVLKSFAQARAFIFIDESHITDAFTWLSKQQKDSGCFRSSGSLFNNAMKG--GVDDEITLSAYITMALLESSLPDTDPVVSKALGCLEASWETIEQGRNGSFVYTKTLMAYAFALAGNQEKRNEILKSLDKEAIREDNSIHWERP----QKPTKSEGYLYTPQASSAEVEMSAYVVLARLTAQPAP-----SPEDLALSMGTIKWLTKQQNSHGGFSSTQDTVVALDALSKYGAATFSKSQKTPLVTIQSSGSFSQKFQVDNSNRLLLQQVSLPDIPGNYTVSVSGEGCVYAQTTLRYNMPLEKQ-QPAFALKVQTVPLTCNNPKGQNSFQISLEISYTGSRPASNMVIADVKMLSGFIPLKP---TVKKLERLEHVSRTEVTTNNVLLYLDQVTNQTLS-FSFIIQQDIPVKNLQPAIVKVYDYYETDEVAFAEYSSPCSSDKQNV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14046-1", "uniprot_id": "A1I3_RAT", "id": "P14046-1", "name": "Alpha-1-inhibitor 3", "aln": "MKKDREAQLCLFSALLAFLPFASLLNGNSKYMVLVPSQLYTETPEKICLHLYHLNETVTVTASLISQRGTRKLFDELVVDKDLFHCVSFTIPR-LPSSEEEESLDINIEGAKHKFSERRVVLVKNKESVVFVQTDKPMYKPGQSVKFRVVSMDKNLHPLNELFPLAYIEDPKMNRIMQWQDVKTENGLKQLSFSLSAEPIQGPYKIVILKQSGVKEEHSFTVMEFVLPRFGVDVKVPNAISVYDEIINVTACATYTYGKPVPGHVKISLCHGNP------TFSSETKSGCKEEDSRLDNNGCSTQEVNITEFQLKENYLKMHQAFHVNATVTEEGTGSEFSGSGRIEVERTRNKFLFLKADSHFRHGIPFFVKVRLVDIKGDPIPNEQVLIKARDAG---YTNATTTDQHGLAKFSIDTNGISDYSLNIKVY--------HKEESSCIHSSCTAERHAEAHHTAYAVYSLSKSYIYLDTEAG-VLPCNQIHTVQAHFILKGQVLGVLQQIVFHYLVMAQGSILQTGNHTHQVEPGESQVQGNFALEIPVEFSMVPVAKMLIYTILPDGEVIADSVKFQVEKCLRNKVHLSFSPSQSLPASQTHMRVTASPQSLCGLRAVDQSVLLQKPEAELSPSLIYDLPGMQDSNFIASSNDPFEDE--DYCLMYQP-----------IAREK----------DVYRYVRETGLMAFTNLKIKLPTYCNTDYDMVPLAVPAVALDSSTDRGMYESLPVVAVKSPLPQEPPRKDPPPKDPVIETIRNYFPETWIWDLVTVNSSGVTELEMTVPDTITEWKAGALCLSNDTGLGLSSVASFQAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPTSLPMAVLLEASPDFTAVP-VENNQDSYCLGANGRHTSSWLVTPKSLGNVNFSVSAEARQSPGPCGSEVATVPETGRKDTVVKVLIVEPEGIKKEHTFSSLLCASDAELSETLSLLLPPTVVKDSARAHFSVMGDILSSAIKNTQNLIQMPYGCGEQNMVLFAPNIYVLKYLNETQQLTEKIKSKALGYLRAGYQRELNYKHKDGSYSAFGDHN-GQGQGNTWLTAFVLKSFAQARAFIFIDESHITDAFTWLSKQQKDSGCFRSSGSLLNNAMKG--GVDDEITLSAYITMALLESSLPDTDPVVSKALSCLESSWENIEQGGNGSFVYTKALMAYAFALAGNQEKRNEILKSLDKEAIKEDNSIHWERP----QKPTKSEGYLYTPQASSAEVEMSAYVVLARLTAQPAP-----SPEDLALSMGTIKWLTKQQNSYGGFSSTQDTVVALDALSKYGAATFSKSQKTPSVTVQSSGSFSQKFQVDKSNRLLLQQVSLPYIPGNYTVSVSGEGCVYAQTTLRYNVPLEKQ-QPAFALKVQTVPLTCNNPKGQNSFQISLEISYMGSRPASNMVIADVKMLSGFIPLKP---TVKKLERLGHVSRTEVTTNNVLLYLDQVTNQTLS-FSFIIQQDIPVKNLQPAIVKVYDYYETDEVAFAEYSSPCSSDDQNV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6IE52-1", "uniprot_id": "MUG2_RAT", "id": "Q6IE52-1", "name": "Murinoglobulin-2", "aln": "MWKNREAQLCLFSVLLAFLPSASLLFGNSKYMVLVPSQLYTETPEKICLHLYHLNETVTVTASLISQRGTRKLFDEPVVDKDLFHCVSF-IPR-LPSSEEEESLDINIEGAKHKFSKRHVVLVKNKESVVFVQTDKPMYKPGQSVKFRVVSMDKNLYPLKELV-----QDPKMNRIMQWQDVKTENGLKQLSFSLSAEPIQGPYKIVVLKQSGVKEEHSFTVMEFVLPRFGVDVKVPNAISVYDEIISVTACDRYTYGKPVLGRVKVRLCHGNP------SFSSETKSACKEENSQLDNNGCSTQEVNITEFQLKENYLKVRQAFHVNATVTEEGTGMEFGGYGRIEVERTRNKFLFLKADSHFRHGIPFFVKVRLVDIKGDPIPNEQVFIKAQEAG---YTNATTTDQHGLAKFSIDTSSISGYSLNIKVY--------HKEENLCIHSSCTAERHAEAHHTAYAVYSLSKSYIYLDTEAG-VLPCNQIHTVQAHFILKGQVLGVLPQIVFHYLVMAQGSILQTGNHTHQVESG-APVQGNFALEIPVEFSMVPMAKMLIYTILPDGEVIADSVKFQVEKCLRNKVHLSFSPSQSLPASQTHMRVTASPQSLCGLRAVDQSVLLLRPEAELSPSLIYDLPGMQDSNFIPRSHHPFEDE--DDCLMYQPRDTEELTYSVPYGREK----------DVYRYV-DMGLTAFTNLKIKHPTYC---YDLP--------------------------KEPPRKDPPRKDPEPKDTVVETIRNYFPETWVWDLVTVSSSGVTEVEMTVPDTITEWKAGALCLSNDTGLGLSSVATLQAFQPFFVELTMPYSVIRGEAFTLKATVMNYLPTSLQMTVQLEASPDFTAVP-VGNDQDSYCLGANGRHTSSWLVTPKSLGNVNFSVSVEAQQSPEPCGSEVATVPETGRKDTVIKVLIVEPEGIKKEHTFSSLLCASDAELSETLSLLLPPRVVKDSARAHFSVMGDILSSAIKNTQNLIQMPYGCGEQNMVLFAPNIYVLKYLNETQQLTENIKSKALGYLRAGYQRELNYKHKDGSYSAFGDHN-GQGQGNTWLTAFVLKSFAQARAFIFIDESHITDAFTWLSKQQKDSGCFRSSGSLFNNAMKG--GVDDEITLSAYITMALLESSLP---PVVSKALGCLEASWETIEQGRNGSFVYTKALMAYAFTLAGNQEKRNEILKSLDKEAIKEDNSIHWERP----QKPMKSEHYLYTPQASSVEVEMSAYVVLARLTAHPAP-----SPEDLALSTGTIKWLTKQQNSHGGFSSTQDTVVALDALSKYGAATFSKSQKTPSVTVQSSGSFSQKFQVDKSNRLLLQQVSLPDIPGNYTIRVSGEGCVYAQTTLRYNLPLEKQ-QPAFALKVKTVPLTCNNPKGQNSFQISLEISYTGSRPASNMVIADVKMLSGFIPLKP---TVKKLERLEHVSRTEVTTNNVLLYLDQVTNQTLS-FSFIIQQDIPVKNLQPAIVKVYDYYETDEVAFAEYSSPCSSDKQNV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28666-1", "uniprot_id": "MUG2_MOUSE", "id": "P28666-1", "name": "Murinoglobulin-2", "aln": "MWKSRRAQLCLFSVLLAFLPSASSLNGDSKYMVLVPSQLYTETPEKICLHLYHLNETVTVTASLVSQTGRRNLFDELVVDKDLFQCVSFIIPT-LNSPDEEEFLYVDIKGPTHEFSKRNAVLVKNKESVVFVQTDKPVYKPGQSVKFRVVSMDKTLRPLNELLPLAYIEDPKKNRIMQWRDIKTENGLKQMSFSLAAEPIQGPYKIVVHKQSGVKEEHSFTVMEFVLPRFNVDLKVPNAISVNDEVLQVTVCGKYTYGKPVPGQVKISICH-------------ETEAGCKEVNSKLDNNGCSTQEVNITELQSKKRNYEV-QLFHVNATVTEEGTGLEFNGYGTTKIERITNKLIFLKADSHFRHGIPFFVKVRLVDIKGDPIPNERVFIKAQVLG---YTSATTTDQHGLAKFSIDTAGFSGSSLHIKVN--------HKGKDSCYFFYCMEERYASAEHVAYAVYSLSKSYIYLVKETSSILPCNQIHTVQAHFILKGD-LGVLKELVFYYLVMAQGSIIQTGNHTHQVEPGEAPVKGNFDLEIPVEFSMAPMAKMLIYTILPDGEVIADSVNFEIEKCLRNKVDLSFSSSQSLPASQTRLQVTASPQSLCGLRAVDQSVLLLKPEDELSPSWIYNLPGMQHNKFIPSS-SLSEDR--EDCILYSSWVAEKHTDWVPHGREK----------DVYRYVEDMDLKAFTNLKIKLPKIC-FDS--APMSGPRGKFDLAFSSEVSGTLQKGSSKRPQPEEPPREDPPPKDPLAETIRKYFPETWVWDIVTVNSTGVAEVEMTVPDTITEWKAGALCLSNDTGLGLSSVVPLQAFQPFFVEVSLPYSVVRGEAFMLKATVMNYLPTSMRMSVQLEASPDFTAVP-VGDDHDSYCLSANGRHTSSWLVTPKSLGNVNFSVSVEAQQSSEPCGSEVATVPETGRKDTVVKVLIVEPEGIKQEHTFNSLFCASDAEISEKMSLVLPPTVVKDSARAHFSVMGDILSSAIKNTQNLLHMPYGCGEQNMVLFAPNIYVLKYLDKTQQLTQKIKTKALGFLRAGYQRELNYKHKDGSYSAFGDQN-GEREGNTWLTAFVLKSFAQARAFIFIDESHITHAFTWLSQQQKDNGCFRSSGSLFHNDIK---------------------------HPVVSKALSCLESSWKTIEQGRNANFVYTKALMAYAFALAGNQDKRNEILKSLDEEAIKEDNSIHWERP----QKPRKSEHNLYKPQASSVEVEMNAYVVLARLTAQPAP-----SPEDLTLSRSTIMWLTKQQNSNGGFSSTQDTVVALDALSKYGAVTFSRRQKTSLVTIQSTGSFSQKFQVENSNCLLLQQVPLPDIPGDYTISVSGEGCVYAQTTLRYNMHLEKQ-QSAFALRVQTVPLTCNNPKGHNSFQISLEISYTGSRPASNMVIADVKMLSGFIPLKP---TVKKLERLEHISRTEVSNNNVLLYLDQVTNQTLA-FSFIIQQDISVRNLQPAIVKVYDYYETDEVAYAEYSSPCSSDKQNV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28665-1", "uniprot_id": "MUG1_MOUSE", "id": "P28665-1", "name": "Murinoglobulin-1", "aln": "MWKSRRAQLCLFSVLLAFLHSASLLNGDSKYMVLVPSQLYTETPEKICLHLYQLNETVTVTASLVSQSGRKNLFDELVLDKDLFQCVSFIIPR-LSSSDEEDFLYVDIKGPTHEFSKRKAVLVKNKESVVFVQTDKPVYKPGQSVKFRVVSMDKMLRPLNELLPLAYIEDPKKNRIMQWRDIKTENGLKQMSFSLAAEPIQGPYKIVVHKESGEKEEHSFTVMEFVLPRFNVDLKVPNAMSVNDEVLSVTACGKYTYGKPVPGHVKINVCR-------------ETETGCREVNSQLDNNGCSTQEVNITELQSKKRNYEV-QLFHVNATVTEEGTGLEFSRSGTTKIERITNKLIFLKADSHFRHGIPFFVKVRLVDIKGDPIPNEKVFIKAQELS---YTSATTTDQHGLAEFSIDTTCISGSSLHIKVN--------HKEEDSCSYFYCMEERHASAKHVAYAVYSLSKSYIYLDTETSSILPCNQIHTVQAHFILKGD-LGVLKELIFYYLVMAQGSIIQTGNHTHQVEPGEAPVKGKFALEIPVEFSMVPMAKMLIYTILPDGEVIADSVNFEIEKCLRNKVDLRFSTSQSLPASQTRLQVTASPQSLCGLRAVDQSVLLLKPESELSPSWIYNLPGMQQNKFVPSS-RLSEDQ--EDCILYSSWLAEKHTNLVPHGTEK----------DVYRYVEDMGLTAFTNLMIKLPIIC-FDYGMVPISAPRVEFDLAFTPEISWSLRTTLSKRP--EEPPRKDPSSNDPLTETIRKYFPETWVWDIVTVNSTGLAEVEMTVPDTITEWKAGALCLSNDTGLGLSSVVPLQAFKPFFVEVSLPYSVVRGEAFMLKATVMNYLPTSMQMSVQLEASPDFTAVP-VGDDQDSYCLSANGRHTSSWLVTPKSLGNVNFSVSAEAQQSSEPCGSEVATVPETGRKDTVVKVLIVEPEGIKQEHTFSSLFCASDAEISEKMSLVLPPTVVKDSARAHFSVMGDILSSAIRNTQNLLHMPYGCGEQNMVLFAPNIYVLKYLNETQQLTQKIKTKALGFLRAGYQRELNYKHKDGSYSAFGDQN-GEREGNTWLTAFVLKSFAQARAFIFIDESHITHAFTWLSQKQKDNGCFRSSGSLFNNAMKG--GVDDEMTLSAYITMALLESSLPATHPVVSKALSCLESSWKTIEQERNASFVYTKALMAYAFALAGNQNKRDEILKSLDEEAIKENNSIHWKRP----QKSRKSEHHLYKPQASSAEVEMNAYVVLARLTAQPAP-----SPEDLTLSMSTIMWLTKQQNSNGGFSSTQDTVVALDALSKYGAVTFSRSQKTTLVTIQSTGSFSQKFQVENSNRLLLQQVALPDIPGDYTISVSGEGCVYAQTMLRYNMHLEKQ-LSAFAIWVQTVPLTCNNPKGHNSFQISLEISYTGSRPASNMVIADVKMLSGFIPLKP---TVKKLERLEHVSRTEVSNNNVLIYLDQVTNQTLA-FSFIIQQDIPVRNLQPAIVKVYDYYETDEMAFAEYSSPCSTDKQNV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0N4SVU1-1", "uniprot_id": "A0A0N4SVU1_MOUSE", "id": "A0A0N4SVU1-1", "name": "", "aln": "MGKSRWAQLCLFSVLLAFLTSASSLNGYSKYMVLVPSQLYTETPEKICLHLYHLNETVTITASLVSQWGRRNLFNELVVDKDLFQCVSFIIPR-FSSSDEEQFLYVDIKGPTHNFSKKEAVLVRNKESVVFVQTDKPVYKPGQSVKFRVVSMDKNLRPLNELFPLAYIEDPKKNRIMQWKDIKTENGLKQISFSLAAEPIQGPYKIVLQKQSGVKEKHSFNVMEFVLPRFDVALKVPNAISVNDEVLSVTACAKYTYGKPVPGYVEISVCH-------------ETEAGCKEVNSQLDNNGCSTQEVNITELQPKKRHHRV-QLFHVNATVTEEGTGLEFSRSGTTKIERTTNKLIFLKADSHFRHGIPFFVKVLLVDIKGDPIPNEKVFIKAQELG---YTSATTTDQQGLAKFCIDTDGFSGSSLHIKVK--------HKEEDSYSHFYCMEERYASADHVAYAVSSLSKSYIYLDTETSSILPCNQIHTVQAHFILKWD-FGVLKELVFYYLVMAQGSIIQTGNHTHQVEPGEAPVKGNFALEIPVEFSMVPLAKMLIYTILPDGEVIADSVNFEIEKCLRNKVDLSFSSSQSLPASQTRLQVTASPQSLCGLRAVDQSVLLLKPEAELSPSWIYNLPGMQHNKFISSS-HLPEDQ--EDCILCGSCVAEKHTNSVPHGREK----------DVYRYVEDMGLMAFTNLKIKHPTFC-FDYDMVPILAPRVEFDLAFSHENTGSLHTVLSKRP--EETPRKDPPSNDPFTETIRKYFPETWVWDIVTVNSTGVAEVEMTVPDTITEWKAGALCLSNDTGLGLSSVAPLQVFQDFFVEVSFPYSVVRGEAFMLKATVMNYLPTSMQMSVQLQDSPDFTAVP-VGDYQDSYCLSAKERYTSSWLVTPKSLGNVNFSVSAEAQQSPEPCGSEVATVPETGRKDTVVKFLIVEPEGIKIEHTFSSLLCASDAEISEKLSLVLPPTVVKDSARAHFSVMGDVLSPAIKNTQNLLHMPYGCGEQNMVLFAPNIYVLKYLNETHQLTQTIKTKALGFLRAGYQRELNYKHKDGSYSAFGDQN-GEREGNTWLTAFVLKSFAQARAFIFIDESHITHSLTWLSQQQKDNGCFQSSGSLFNNAMKG--GVDDEMTLSAYITMALLESSLPATHPVVSKALSCLELSWKTIEQERNASFVYTKALMAYAFALVGNQDKRDEILKSLDEEAIKENNSIHWKRP----QKPRKSEHHLYKPQASSAEVEMNAYVVLARLTAQPAP-----SPEDLTLSMSTIMWLTEQQNSNGGFSSTQDTVVALDALSKYKAVTFSRSQKTTLVTIQSSGSFSQKFQVENSNRLLLQQVALPDIPGDYTMSVSGEGCVYAQTTLRYNIHLEKQ-PSAFALRVQTVPLTCNDPKGHNSFQISLEISYTGSRPASNMVIADVKMLSGFIPLKP---TVKKLESLAPVRRTEVSSNNVLLYLDQVNSHTLA-FSFIIQQDFLVRNLQPAMVKVYDYYETDEVAFAEYSNPCRTDKQNI--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20742-1", "uniprot_id": "PZP_HUMAN", "id": "P20742-1", "name": "Pregnancy zone protein", "aln": "MRKDRLLHLCLV-LLLILLSASDSNSTEPQYMVLVPSLLHTEAPKKGCVLLSHLNETVTVSASLESGRENRSLFTDLVAEKDLFHCVSFTLPR-ISASSEVAFLSIQIKGPTQDFRKRNTVLVLNTQSLVFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQSLKLEAGINQLSFPLSSEPIQGSYRVVVQTESGGRIQHPFTVEEFVLPKFEVKVQVPKIISIMDEKVNITVCGEYTYGKPVPGLATVSLCRKLSR-----VLNCDKQEVCEEFSQQLNSNGCITQQVHTKMLQITNTGFEM--KLRVEARIREEGTDLEVTANRISEITNIVSKLKFVKVDSHFRQGIPFFAQVLLVDGKGVPIPNKLFFISVNDAN---YYSNATTNEQGLAQFSINTTSISVNKLFVRVF--------TVHPNLCFHYSWVAEDHQGAQHTANRVFSLSGSYIHLEPVAG-TLPCGHTETITAHYTLNRQAMGELSELSFHYLIMAKGVIVRSGTHTLPVESG--DMKGSFALSFPVESDVAPIARMFIFAILPDGEVVGDSEKFEIENCLANKVDLSFSPAQSPPASHAHLQVAAAPQSLCALRAVDQSVLLMKPEAELSVSSVYNLLTVKDLTNFPDNVDQQEEE--QGHCPRPFFIHNGAIYVPLSSNEA----------DIYSFLKGMGLKVFTNSKIRKPKSC----SVIPSVSAGAVGQGYYGAGLGVVERPYVPQLGTYNVIPLNNEQSSGPVPETVRSYFPETWIWELVAVNSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEVFTLKATVLNYLPKCIRVSVQLKASPAFLASQ-NTKGEESYCICGNERQTLSWTVTPKTLGNVNFSVSAEAMQSLELCGNEVVEVPEIKRKDTVIKTLLVEAEGIEQEKTFSSMTCASGANVSEQLSLKLPSNVVKESARASFSVLGDILGSAMQNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLNETQQLTQEIKAKAVGYLITGYQRQLNYKHQDGSYSTFGERY-GRNQGNTWLTAFVLKTFAQARSYIFIDEAHITQSLTWLSQMQKDNGCFRSSGSLLNNAIKG--GVEDEATLSAYVTIALLEIPLPVTNPIVRNALFCLESAWNVAKEGTHGSHVYTKALLAYAFSLLGKQNQNREILNSLDKEAVKEDNLVHWERP----QRPKAPVGHLYQTQAPSAEVEMTSYVLLAYLTAQPAP-----TSGDLTSATNIVKWIMKQQNAQGGFSSTQDTVVALHALSRYGAATFTRTEKTAQVTVQDSQTFSTNFQVDNNNLLLLQQISLPELPGEYVITVTGERCVYLQTSMKYNILPEKE-DSPFALKVQTVPQTCDGHKAHTSFQISLTISYTGNRPASNMVIVDVKMVSGFIPLKP---TVKMLERSSSVSRTEVSNNHVLIYVEQVTNQTLS-FSFMVLQDIPVGDLKPAIVKVYDYYETDESVVAEYIAPCSTDTEHGNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61838-1", "uniprot_id": "PZP_MOUSE", "id": "Q61838-1", "name": "Pregnancy zone protein", "aln": "MRRNQLPTPAFLLLFLLLPRDATTATAKPQYVVLVPSEVYSGVPEKACVSLNHVNETVMLSLTLEYAMQQTKLLTDQAVDKDSFYCSPFTISG-SPLP--YTFITVEIKGPTQRFIKKKSIQIIKAESPVFVQTDKPIYKPGQIVKFRVVSVDISFRPLNETFPVVYIETPKRNRIFQWQNIHLAGGLHQLSFPLSVEPALGIYKVVVQKDSGKKIEHSFEVKEYVLPKFEVIIKMQKTMAFLEEELPITACGVYTYGKPVPGLVTLRVCRKYSRYR-STCHNQNSMSICEEFSQQADDKGCFRQVVKTKVFQLRQKGHDM--KIEVEAKIKEEGTGIELTGIGSCEIANALSKLKFTKVNTNYRPGLPFSGQVLLVDEKGKPIPNKNITSVVSPLG---YLSIFTTDEHGLANISIDTSNFTAPFLRVVVT--------YKQNHVCYDNWWLDEFHTQADHSATLVFSPSQSYIQLELVFG-TLACGQTQEIRIHYLLNEDIMKNEKDLTFYYLIKARGSIFNLGSHVLSLEQG--NMKGVFSLPIQVEPGMAPEAQLLIYAILPNEELVADAQNFEIEKCFANKVNLSFPSAQSLPASDTHLKVKAAPLSLCALTAVDQSVLLLKPEAKLSPQSIYNLLPGKTVQGAFFGVPVYKDH--ENCISGEDITHNGIVYTPKHSLGDN---------DAHSIFQSVGINIFTNSKIHKPRFCQEFQHYPAMGGVA-PQALAVAAS-GPGSSFRAMGVPMMGLDYSDEINQVVEVRETVRKYFPETWIWDLVPLDVSGDGELAVKVPDTITEWKASAFCLSGTTGLGLSSTISLQAFQPFFLELTLPYSVVRGEAFTLKATVLNYMSHCIQIRVDLEISPDFLAVP-VGGHENSHCICGNERKTVSWAVTPKSLGEVNFTATAEALQSPELCGNKLTEVPALVHKDTVVKSVIVEPEGIEKEQTYNTLLCPQDTELQDNWSLELPPNVVEGSARATHSVLGDILGSAMQNLQNLLQMPYGCGEQNMVLFVPNIYVLNYLNETQQLTEAIKSKAINYLISGYQRQLNYQHSDGSYSTFGNHGGGNTPGNTWLTAFVLKAFAQAQSHIFIEKTHITNAFNWLSMKQKENGCFQQSGYLLNNAMKG--GVDDEVTLSAYITIALLEMPLPVTHSAVRNALFCLETAWASISQSQE-SHVYTKALLAYAFALAGNKAKRSELLESLNKDAVKEEDSLHWQRPGDVQK-VKALS--FYQPRAPSAEVEMTAYVLLAYLTSESSRPTRDLSSSDLSTASKIVKWISKQQNSHGGFSSTQDTVVALQALSKYGAATFTRSQKEVLVTIESSGTFSKTFHVNSGNRLLLQEVRLPDLPGNYVTKGSGSGCVYLQTSLKYNILPVADGKAPFALQVNTLPLNFDKAGDHRTFQIRINVSYTGERPSSNMVIVDVKMVSGFIPMKP---SVKKLQDQPNIQRTEVNTNHVLIYIEKLTNQTLG-FSFAVEQDIPVKNLKPAPIKVYDYYETDEFTVEEYSAPFSDGSEQGNA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63041-1", "uniprot_id": "A1M_RAT", "id": "Q63041-1", "name": "Alpha-1-macroglobulin", "aln": "MRRNQLPIPVFLLLLLLLPRDATAATGKPRYVVLVPSELYAGVPEKVCVHLNHLNETVTLNVTLEYGVQYSNLLIDQAVDKDSSYCSSFTISR-PLSP--SALIAVEIKGPTHHFIKKKSMWITKAESPVFVQTDKPIYKPGQTVKFRVVSVDISFRPVNETFPVVYIENPKRNRIFQWQNVDLPGGLHQLSFPLSVEPALGIYKVVVQKDSGKKIEHSFEVKEYVLPKFEVQVKMPKTMAFLEEELVVTACGLYTYGKPVPGLVTMKVCRKYTQSY-SNCHGQHSKSICEEFSKQADEKGCFRQVVKTKVFQPRQKGYDM--KIEVEAKIKEDGTGIELTGTGSCEIANTLSKLKFTKANTFYRPGLPFFGQVLLVDEKGQPIPNKNLTVQVNSVR---SQFTFTTDEHGLANILIDTTNFTFSFMGIRVI--------YKQNNICFDNWWVDEYHTQADHSAARIFSPSRSYIQLELVLG-TLACGQTQEIRIHFLLNEDALKDAKDLTFYYLIKARGSIFNSGSHVLPLEQG--KVKGVVSFPIRVEPGMAPVAKLIVYTILPNEELIADVQKFDIEKCFANTVNLSFPSAQSLPASDTHLTVKATPLSLCALTAVDQSVLLLKPEAKLSPQSIYNLLPQKAEQGAYLGPLPYKGG--ENCIKAEDITHNGIVYTPKQDLNDN---------DAYSVFQSIGLKIFTNTRVHKPRYCPMYQAYPPLPYVGEPQALAMSAIPGAGYRSSNIRTSSMMMMGASEVAQEVEVRETVRKYFPETWIWDMVPLDLSGDGELPVKVPDTITEWKASAFCLSGTTGLGLSSTISHKVFQPFFLELTLPYSVVRGEAFILKATVLNYMPHCIRIHVSLEMSPDFLAVP-VGSHEDSHCICGNERKTVSWAVTPKSLGEVNFTATAEALQSPELCGNKVAEVPALVQKDTVVKPVIVEPEGIEKEQTYNTLLCPQDAELQENWTLDLPANVVEGSARATQSVLGDILGSAMQNLQNLLQMPYGCGEQNMVLFVPNIYVLEYLNETQQLTEAIKSKAISYLISGYQRQLNYQHSDGSYSTFGDRGMRHSQGNTWLTAFVLKAFAQAQSYIYIEKTHITNAFNWLSMKQRENGCFQQSGSLLNNAMKG--GVDDEVTLSAYITIALLEMPLPVTHSVVRNALFCLETAWASISNSQE-SHVYTKALLAYAFALAGNRAKRSEVLESLNKDAVNEEESVHWQRPKNVEENVREMRSFSYKPRAPSAEVEMTAYVLLAYLTSASSRPTRDLSSSDLTTASKIVKWISKQQNSHGGFSSTQDTVVALQALSKYGAATFTKSNKEVSVTIESSGTVSGTLHVNNGNRLLLQEVRLADLPGNYITKVSGSGCVYLQTSLKYNILPEAEGEAPFTLKVNTLPLNFDKAEHHRKFQIHINVSYIGERPNSNMVIVDVKMVSGFIPVKP---SVKKLQDQSNIQRTEVNTNHVLIYIEKLTNQTMG-FSFAVEQDIPVKNLKPAPVKVYDYYETDEFAIEEYSAPFSSDSEQGNA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZS19-1", "uniprot_id": "D3ZS19_RAT", "id": "D3ZS19-1", "name": "", "aln": "-------MVPTIVLSALVLHLTNVVASEPRYLLWVSAVVQRFSSEKACLHLVNLNEPVSLSVILEYAGVNTTIFDQRVKEGNFYACANFKVSH-VSPE-QLAFVTLLVQQNTLIISERRAVAVAAEENATFVQTDTPVHKPGDTVHFRVVTLNTWLKPVDELYPLITVQNPQGNVIFQWINVTTFRNITQLSFQLTPEPVLGDYMIVIKKQSGMTVVDHFTVNQDVLPRFEVELTAPETITIADNQFPVVMCAKYIYGQPVRGKAQIKVCRELFSP---GYCESNENEICEQFTLQLKD-GCASYIVNTKVFQLYRSGLFM--TLNINGVITESGTGVQISKTHSVFITSVLGTVSFENMDSFYRRGIPYFGTLKFSGPNNTPMVNKLLQLELDGK----PLGNYTTDEKGEAQFSINTSEIFEAQMSLKAT--------YVRPRSCHRSSWLDPEYLDAYFSASRFYSQTSSFMKIILEPK-PLPCDQEKMVSVLYSLNPEVYKEASKVTFFYLVMVRGSILLSGQTEVKVQAQ----NGNFSFPIIVTADLAPAADLFVYTLHPSGEIVADSVKLQTEKCFKNKVSIKFSKEQDLPGSNTSLHLQAAPGSFCALRAVDKSALLLNHGQEMTPESVYNMLPYVHQYGYFYNGLNLDDERADPCIPQKDLFHNGLYYKPTSNVWDG---------DLSNLVRNMALKIFTNIRYRKPEVCSSQENQPLLRTFNDPNERIMMYGGGGG--GGAPAASAFHDAPDSISHAKVAIKETVRTNFPKTWLWNLISVDSSGSTNVSFLVPDTITQWQASTFCVNGNAGFGISPKVSLQISQPFFMEVTSPFSVVRSEQSDLIVTVFNYRTTCVEISVQLEASENYEASINTQSNTDSEVLPAGEQKTYVWTVTPKTLGKVNITVVATSKQS-SACPNDAHEEQDVNWKDTVVKTLLVEPEGIEKESTQSFLICPKGTKASKQITLELPNDVVEGSARSFVTFVGDILGVAMQNLESLLQTPYGCGEQNIAQLAADIYILDYLNATKQLTEEVRSKALLLLSKGYQKHLSFKNYDGSYDVFCHNN---QEGSVWLSALSFKTFEKMKEYIFIEETVPKQTLIWLVKKQKSNGCFRKNENLVNNAQE--DSDEDDIALTAYVVGAFLEGGLNSSFPALRNGLYCLEEAFSSS-----VTDDHTQAIMAYVFTLAGKQQQVKSLLPILDRSATKTNNMIYWEKD----EKPKADSSPSFIPSALSGETEKTCYVLLAVLSQ---------DTPDLDYASKIVQWLAQRMNSHGGFSAVQDTTVCLLALTRYMKLTGSNPQNTITLSTEES---EEVFHINRDNRLLVQHSKVSEGHRRYTVDVEGDGCSFTQATLRYNVPLPKE-ASGFSLSVKTRKSNSSD-ELQTKFDLMVTLTYTGAHESSGTVLVDVRMLSGFTPVFS---SIEELKFNGQAMKTDIKNGHVLFYLKNVPKAATS-FTFSIEQTNLVVNIQPAPVTVHS-YEKDEYAFDSYNINSISDSQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UU35-1", "uniprot_id": "OVOS_MOUSE", "id": "Q3UU35-1", "name": "Alpha-2-macroglobulin-like protein 1", "aln": "-------MVPTILLSALLLHFTDVVAAEPRYILWVSSVVQRFSSEKACLHLLNLNESVSLSVTLEYDGSSTTIFDQPVDEGNFYACADFKVSQ-MSSE-QLAFVALLVQGNTLKISERRSVAIAAEENATFVQTDTPVHKPGDTVHFRVVTLNIWLKPVDDLYPLITVQDPQSNVIFQWINVTTFRNITQLSFQLTPEPILGDYTIVIKTQSGTTVMDHFTVNRDVLPKFEVELTAPETITIADSQFQMVTCAKYTYGQPVQGKAQIKVCRELFSP---AHCESNENEICEQFTVQLKD-GCASHIINTKVFQLDRSGLFM--TLNVNEVVTESGTGVQMSKTHSVFITSVLGTVSFENMDPFYRRGITYFGTLKFSGPNNTPLVDKLLQLELDGK----PVGNYTTDENGEARFSINTSEIFGAQISLKAV--------YVRPRSCHRSSWLSPEYLDAYFSASRFYSQTSSFTKIILEPK-QLPCDQEKMFSVLYSLNPEAYKEASDVTFFYLVMVRGGISRSGQKQVRVQAW----NGNFSFPISINADLAPSADLFVYTLHPSGEIVADNVRLQIEKCFKNKVSINFSRDKDLPGSNTSVHLQAAPDSFCALRAVDKSALLLNHGQEMTPESVYFTLPYIHQYGYFYNGLNLDDQQAEPCIPQKDLFYNGLYYTPTGNIWDG---------DLSNLLSNMGLKIFTNLHYRKPEVCSSQENQPLLRTFDHPNERIMMYG------GGAPPSSAFHDSVDSISHAKVAIKETVRTNFPRTWIWNLVSVDSSGTANVSFLVPDTITQWEASAFCVNGNAGFGISPKVSLQISQPFFVEVTSPFSVVRSEQSDMVVTVFNYLTTCVEISVQLEASENYEASINTQRNTDSEVLQAGEQKTYVWTIIPKTLGKVNVTVVATSKQS-RACPNDASKEQDVHWKDTVVKTMLVEAEGIEKEATQSFLICPKGTKASKQTLLELPSNVVEGSVRSFVTIVGDILGVAMQNLESLLQMPYGCGEQNIAQLASDVYILDYLKATDQLTEELKSKAQRLLSNGYQNHLSFKNYDGSYDVFCQSN---QEGSTWLSALSFKTVEKMKEYIFIEETVPKQTLIWLVKKQKSNGCFRRDEKHVDTAQEGREGDQEDIALTAYVVGVFLEVGLNASFPALRNGLYCLEEAFSNG-----VTNGYTQAILAYVFALAGKEQQAKSLLSILDKSATKTNNMIYWERD----EKPETDNSPSFIPSALSGETEKTCYVLLAVLSQ---------DTQDLDYASKIVQWLAQRMNSHGGFSAMQDTTVCLLALTQYMKLTGSNPQNTITLSSEES---EEVFYVNRNKRLLVQHSKVSKGHQQYTVDVEGDGCSFIQATLRYNVPLPKE-ASGFSLSVKTGKSNSSD-EFQTKFELTVTLTYTGARESSVTVLVDVKMLSGFTPVVS---STEELKFNSQVTKTDIKNGHVLFYLENVPKEATS-LTFSIEQTNHVANIQPAPVTVYS-YEKGEYAFDSYNINSISDSQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8K2U0-1", "uniprot_id": "A2ML1_HUMAN", "id": "A8K2U0-1", "name": "Alpha-2-macroglobulin-like protein 1", "aln": "--------MWAQLLLGMLALSPAIAEELPNYLVTLPARLNFPSVQKVCLDLSPGYSDVKFTVTLETKDKTQKLLEYSGLKKRHLHCISFLVPPPAGGTEEVATIRVSGVGNNISFEEKKKVLIQRQGNGTFVQTDKPLYTPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGIVDLSFQLAPEAMLGTYTVAVAEG-KTFG--TFSVEEYVLPKFKVEVVEPKELSTVQESFLVKICCRYTYGKPMLGAVQVSVCQKANTYWYREVEREQLPDKCRNLSGQTDKTGCFSAPVDMATFDLIG--YAYSHQINIVATVVEEGTGVEANATQNIYISPQMGSMTFEDTSNFYHPNFPFSGKIRVRGHDDSFLK-NHLVFLVIYGTNGTFNQTLVTDNNGLAPFTLETSGWNGTDVSLEG--------KFQMEDLVYNPEQVPRYYQNAYLHLRPFYSTTRSFLGIHRLNG-PLKCGQPQEVLVDYYIDPADASPDQEISFSYYLIGKGSLVMEGQKHLNSKKKGLKAS--FSLSLTFTSRLAPDPSLVIYAIFPSGGVVADKIQFSVEMCFDNQVSLGFSPSQQLPGAEVELQLQAAPGSLCALRAVDESVLLLRPDRELSNRSVYGMFPFWYG-HYPYQVAEYDQCPVSGPWDFPQPLIDPMPQGHSSQRSIIWRPSFSEGTDLFSFFRDVGLKILSNAKIKKPVDCSHRSPEYSTAMGAGGGH---------------------PEAFESSTPLHQAEDSQVRQYFPETWLWDLFPIGNSGKEAVHVTVPDAITEWKAMSFCTSQSRGFGLSPTVGLTAFKPFFVDLTLPYSVVRGESFRLTATIFNYLKDCIRVQTDLAKSHEYQLES-WADSQTSSCLCADDAKTHHWNITAVKLGHINFTISTKILDSNEPCGGQKGFVPQKGRSDTLIKPVLVKPEGVLVEKTHSSLLCPKGKVASESVSLELPVDIVPDSTKAYVTVLGDIMGTALQNLDGLVQMPSGCGEQNMVLFAPIIYVLQYLEKAGLLTEEIRSRAVGFLEIGYQKELMYKHSNGSYSAFGERD---GNGNTWLTAFVTKCFGQAQKFIFIDPKNIQDALKWMAGNQLPSGCYANVGNLLHTAMKG--GVDDEVSLTAYVTAALLEMGKDVDDPMVSQGLRCLKNSATST------TNLYTQALLAYIFSLAGEMDIRNILLKQLDQQAIISGESIYWSQK------PTPSSNASPWSEPAAVDVELTAYALLAQLTKPSLT------QKEIAKATSIVAWLAKQHNAYGGFSSTQDTVVALQALAKYATTAYM-PSEEINLVVKSTENFQRTFNIQSVNRLVFQQDTLPNVPGMYTLEASGQGCVYVQTVLRYNILPPTN-MKTFSLSVEIGKARCEQPTSPRSLTLTIHTSYVGSRSSSNMAIVEVKMLSGFSPMEG---TNQLLLQQPLVKKVEFGTDTLNIYLDELIKNTQT-YTFTISQSVLVTNLKPATIKVYDYYLPDEQATIQYSDPCE--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13AAT6-1", "uniprot_id": "A0AB13AAT6_DANRE", "id": "A0AB13AAT6-1", "name": "", "aln": "MALIVSCCLKGFFLIFILFLCVNGNKTRPIFMVTFPAVIESGSDAKLCASLLKPNKTLFMNIYLVHSNQSTLLLQEKAEQEFHR-CFNFQAP--LAEAESVQKIKVELQGESFNMTEERKVMFKSYHPLTFIQMDKPFYIAGQTVNFRVVTMDKSFRPLDQQYSAVVLEDSQDNRIGQWTNVSSTRWILQRSYDLNPEAREGTYKVKAFIG-ERMISHDFDVKKYVLPKFGVFVISPNPVSIDDEFMVIEVCGKYTYGKPVLGKSSVKVCRKT---------LDTHSPLCVKESTEISKTGCANHTLALSVFFYPTH-HQLLNDLHIEATITEEETEITMTQSNTISLTYEIGKVTFTDLPKTYEYGSVIEGKVKLARFRGTAVPGKHIYILENYSWPPKVLLNLTTDSNGLANFSLNTLRFVKSDINLMASAYPGYRSYFQKSPYFNTDEKTVQFFP----KPAASYTPTFSELIIENIEQ-PLKCGTEITATVKYYFVKETVKIFN-ADIVYMVLSRGVIIHHGYEKVEVKSSNAVASGTMSFKLSVGADVAPLVQILAYCVLPSENIAIHSENFHVEKCLKNKVSLQFSPAKAVPGEKNTLQLSAQPGSLCGLSAVDQSVLMLESGKRLDADKIFNLLPVKYGSGYPSSLPDEKEC-----FYMMAVPIENIFK--SSKR--------------------IGLKMATNLAVRS---GTSTCEMYKKFMFRDIG------------------------LAEDSVPHWTLFEENVRSVFPKTWLWQLIEISDSGSAEVPVTVPDTITSWETEAFCLS-STGLGLAPPAQLTVFQPFFLELSLPYSIIRGEMFELKATVFNYLSKCIMVKVSPAPSSDYTLKA-SSDDQYSSCLCANGRKTFKWILTPSVIGVVNVTVRAEAEASQTVCDNEIVSVPERGRIDTVTRSLLVQAEGIKKAKTNSWLLCPKGDSLLEEIDLTLPKDMIEGSVTSSVSVIGDIVGRSLKKLHRTLWRIYRSGNQNIAILSPSIYILQYLENTKQLTSAIREKASSFLKSGYQRQLKYRHRNGAYSTFG--N---GKGNAWLTAFVLKSFVKAQKYIYIDPQIIKSAKKWLIGTQDPEGCFIQHGRLFNNRLKG--GVSDHVTMTAYITASLLELETSVTDPVIIKGLSCLRSVIKDV------KNTYTTALLAYTFSLARDTNTRQQLFNKLEDLAISDGPLVHWSQS------ASADDSDS-------LDVEISSYVLLAVLTADSLT------TADLGFANRIVSWLVKQQNAYGGFSSTQDTVVALQALSLYATKVFS-SDGSSTVTVQSAG-DSHYFNVNQDNKLVYQEKQLANVPGKYKIEVKGSACVSVQMAQFYNILTPKE-VKTLSIDVKI-EGDCKKTFG-NKLLLEFTVNYDGPHETTNMLIVDVKLLSGFTADDTTMFGSSSGFYVPLVEQVDYKDDHVIVYLKEVPKHFPVNYQIQMKQVLHVMNLKPAVIKVYDYYQTSDQSETEYYFHC---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . ::: ..: : * * * . : .. * :: . * * . : : . : :.. : . .*:* *.*.: .*: * **:*::: : * .: : .. * * ** .: : : *: * *. * * : * * . ***:* * : : :: :. . : * * **:*: * : :*: * : . .. ** : : :.: : *. * : ... * . :. . : . . : : . .*:.:* * : ::* : : . : : * : * *. : : : * : :* : * : . . : : . :.* :. : : *. : . : * *: * * : *. : *. . : : * * *:*.* ***:*.*: . .: :: . : :* : . . :* **.**:*::. :. :* : . ***:**.*:: ::* . *:*::. : **:::: *:*::*.* : .*::** .: : . * : * : . * * : . :* :*.: . * * .. **: : ::*:.**: * . : *... . * ** :: *. : :.:**::. :::: . : .*:**:. : . :*:*.**. : **. :: :* * ***..* ::: :*:*..* *..**:*: * . : : .*:*: : *: * .**: ... : . : :.* **. . :* :::** *:* . :: *: * ::*.: :.* ..*.:** *: :: : : *: :: *: ****: ***.*.* **: * . . : :.: . : :: : *: *. :. * *. * * **: : ::: *: . .: : . .* * : : :.:*:::*** . . :.: . : .*:.:: . : : * * :::** :.*:. * .: .* ", "identical_positions": 202, "similar_positions": 371, "identity": "13.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1346", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70503-1", "uniprot_id": "DHB12_MOUSE", "id": "O70503-1", "name": "Very-long-chain 3-oxoacyl-CoA reductase", "aln": "---MECAPPAAGFLYWVGASTIAYLALRASYSLFRAFQVWCVGN-EALVG--------PRLGEWAVVTGGTDGIGKAYAEELAKRGMKIVLISRSQDKLNQVSNNIKEKFNVETRTIAVDFS--LDDIYDKIKTGLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDN-TIKKLININVLSVCKVTRLVLPGMVE---------RSKGVILNISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEYKSKGIFVQSVMPYLVATKLAKIQKPTLDKPSAETFVKSAIKTVGLQTRT-------TGYVIHSLMGSINS----IMPRWMYFKIIMGFSKSLRNRYLKKRKKN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P7R8-1", "uniprot_id": "DHB12_RAT", "id": "Q6P7R8-1", "name": "Very-long-chain 3-oxoacyl-CoA reductase", "aln": "---MERALPAAGFLYWVGASTIAYLTLRASYSLFRAFQVWCVGN-QAFVG--------PRLGEWAVVTGGTDGIGKSYAEELAKRGMKIVLISRSQDKLKEVSNNIKEKFNVETRTIAVDFS--LDDIYDKIKTGLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDN-TIKKLININVLSICKVTRLVLPGMVE---------RSKGVILNISSASGMLPVPLLTVYSATKAFVDFFSQCLHEEYKSKGIFVQSVLPFFVATKLAKIRKPTLDKPSAETFVKSAIKTVGLQTRT-------TGYVIHAIMGSINS----ILPRWIYFKTIMGFNKSLRNRYLKKTKKN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q53GQ0-1", "uniprot_id": "DHB12_HUMAN", "id": "Q53GQ0-1", "name": "Very-long-chain 3-oxoacyl-CoA reductase", "aln": "---MESALPAAGFLYWVGAGTVAYLALRISYSLFTALRVWGVGN-EAGVG--------PGLGEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFA--SEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDN-VIKKMININILSVCKMTQLVLPGMVE---------RSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVGLQSRT-------NGYLIHALMGSIIS----NLPSWIYLKIVMNMNKSTRAHYLKKTKKN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6QA33-1", "uniprot_id": "DH12B_DANRE", "id": "Q6QA33-1", "name": "Very-long-chain 3-oxoacyl-CoA reductase-B", "aln": "---ME---PFADALFWVGAVTVLWLSVSSLWSLINGIRVWILGNGNLMRA--------SSLGKWAVVTGATDGIGKAYAEELARRGFAIVLISRTQEKLDEVSKAIESKYKVETKTISADFG--SVDIYPKIESGLAGLEIGVLVNNVGVSYSYPEFFLNIPDVDS-FINNMININIMSVCQMTRLVLPRMVD---------RSKGVILNVASASGMYPVPLLTLYSSTKAFVDFFSRGLDAEYKSKGIIIQSVLPFYVTTKLSKIRKPTLDIPTPERYVKAQLSTIGLQTQS-------NGYLPHAIMGWVTAS---LLPAKLLNKYVMGMGLSQRARYLKKQKQG----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3N1-1", "uniprot_id": "Q9W3N1_DROME", "id": "Q9W3N1-1", "name": "", "aln": "---MEE--NNSQVLSLLGGLAIGIVGFQVFRKVLPWIYANVVGP-KVFGSSV----DLSKMGEWAVVTGSTDGIGKAYAKELARRGLKLVLISRSLEKLNVVAKEIGDKYGVEVRVIDVDFTG-GDEIYDKIREKTTGLNVGVLVNNVGISYGHPEYFLDCYKADPPFLRNIVAANIHSVTHMTALFLPGMIS---------QRRGVIINVSSTAGVIPNPLLSVYSSTKAFVNKFSDDLQTEYKEHGILIQSVQPGFVATNMSKIRKASVFAPSPETYVRSALSTLGIATQT-------AGYLPHALLQLVIHFTEAVFGEQFARNIVMKNILGTRKRALRRLAKEQ---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38286-1", "uniprot_id": "MKAR_YEAST", "id": "P38286-1", "name": "Very-long-chain 3-oxoacyl-CoA reductase", "aln": "MTFMQQLQEAGERFRCINGLLWVVFGLGVLKCTTLSLRFLALIFDLFLLPAVNFDKYGAKTGKYCAITGASDGIGKEFARQMAKRGFNLVLISRTQSKLEALQKELEDQHHVVVKILAIDIAEDKESNYESIKELCAQLPITVLVNNVGQSHSIPVPFLETEEKEL---RNIITINNTATLLITQIIAPKIVETVKAENKKSGTRGLILTMGSFGGLIPTPLLATYSGSKSFLQGWSNSLAGELSKDAIDVELIISYLVTSSMSKIRRSSLMIPNPQQFVKSTLRSVGRRCGSQERYATMTPYWAHAVYQFVITET-FGVYSKIVNSINYSFHKSIRIRALKKAARQVKKE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . : :.. . . : : . *::..:**.:***** :*.::*::*: :*****: .**. : . : .:. * .: : *: . * .*. : * : :****** *: * **: . : .::: * : :* :. * ::. :* *:.:.* .*: * ***: **.:*:*:: :* * * ...: :: : . *::.::**::.:: *..: :*:: : ::* : * *:: : . : . . * : *:: : ", "identical_positions": 62, "similar_positions": 113, "identity": "17.66%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1365", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYA2-1", "uniprot_id": "TOM40_MOUSE", "id": "Q9QYA2-1", "name": "Mitochondrial import receptor subunit TOM40 homolog", "aln": "MGNVLAASSPPAGPPPPPTPSLVGLPPPPPSPPGFTLPPLGGGLGTGSSTGRGSERTPGAAASGAAAASEDGSCGCLPNPGTFEECHRKCK---ELFPVQMEGVKLTVNKGLSN--RFQVTHTVALGTIGESNYHFGVTYVGTKQLSPTEAFPVLVGDMDNSGSLNAQVIHQLSPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTAAVTLGNPDVLVG---SGILVAHYLQSITPCLALGGELVYHRRP---GEEGTVMSLAGKYTLN--NWLATVTLGQ-AGMHATYYHKASDQLQVGVEFEASTRMQ-----------------DTSASFGYQLDLPKANFLFKGSVNSNWIVGATLEKKLPPLPLTLSLCAFLNHRKNKFLCGFGLTIG---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q75Q40-1", "uniprot_id": "TOM40_RAT", "id": "Q75Q40-1", "name": "Mitochondrial import receptor subunit TOM40 homolog", "aln": "MGNVLAASSPPAGPPPPPTPSLVGLPPPPPSPPGFTLPPLGGGLGTGSNAGRGSERTPGAAASGAAASSNDGNCGCLPNPGTFEECHRKCK---ELFPVQMEGVKLTVNKGLSN--RFQVTHTVALGTIGESNYHFGVTYVGTKQLSPTEAFPVLVGDMDNSGSLNAQVIHQLSPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTAAVTLGNPDVLVG---SGILVAHYLQSITPCLALGGELVYHRRP---GEKGTVMSLAGKYTLN--NWLATVTLGQ-AGMHATYYHKASDQLQVGVEFEASTRMQ-----------------DTSASFGYQLDLPKANFLFKGSVNSNWIVGATLEKKLPPLPLTLSLCAFLNHRKNKFLCGFGLTIG---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O96008-1", "uniprot_id": "TOM40_HUMAN", "id": "O96008-1", "name": "Mitochondrial import receptor subunit TOM40 homolog", "aln": "MGNVLAASSPPAGPPPPPAPALVGLPPPPPSPPGFTLPPLGGSLGAGTSTSRSSERTPGAATASASGAAEDGACGCLPNPGTFEECHRKCK---ELFPIQMEGVKLTVNKGLSN--HFQVNHTVALSTIGESNYHFGVTYVGTKQLSPTEAFPVLVGDMDNSGSLNAQVIHQLGPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTAAVTLGNPDVLVG---SGILVAHYLQSITPCLALGGELVYHRRP---GEEGTVMSLAGKYTLN--NWLATVTLGQ-AGMHATYYHKASDQLQVGVEFEASTRMQ-----------------DTSVSFGYQLDLPKANLLFKGSVDSNWIVGATLEKKLPPLPLTLALGAFLNHRKNKFQCGFGLTIG---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z1R1-1", "uniprot_id": "A0A8M6Z1R1_DANRE", "id": "A0A8M6Z1R1-1", "name": "", "aln": "MRRESSSSCWYTSFLTMGSVLAASSPNPPPASGGGTAP-AGAGLVTVPPGFTMPPVSGVPPSSGTQGQPGTDSESSLPNPGTFEECHRKCK---EVFPVQMEGVRLVVNKGLSN--HFQVSHTITLSTLGDSGYRFGSTYVGSKQTGPAESFPVMVGDMDNTGSLNAQVIHQLTNRVRSKIAIQTQQHKFVNWQCDGEYRGDDFTAAVTLGNPDVLVG---SGILVAHYLQSLSPSLVLGGELVYHKRP---GEEGTVTSLVGRYTGS--NYVATLTVGG-AGAHASYYHKANDQLQVGVEFEASTRMQ-----------------ETSVSFGYQLDVPKANLLFKGSLDSNWVVGATLEKKLLPLPLSLALGAFLNHRKNKFQCGFGVTIG---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9U4L6-1", "uniprot_id": "TO401_DROME", "id": "Q9U4L6-1", "name": "Mitochondrial import receptor subunit TOM40 homolog 1", "aln": "MGNVLAASSGAPGS--GASNLGLGLQEPAPLPSN------SGSLTESSSSAEGLDSLAAAKDA------------ALENPGTVEELHKKCK---DIQAITFEGAKIMLNKGLSN--HFQVSHTINMSNVVPSGYRFGATYVGTKEFSPTEAFPVLLGDIDPAGNLNANVIHQFSARLRCKFASQIQESKVVASQLTTDYRGSDYTLSLTVANPSIFTN---SGVVVGQYLQSVTPALALGSELAYQFGPNVPGRQIAIMSVVGRYTAG--SSVWSGTLGQ-SGLHVCYYQKASDQLQIGAEVETSLRMQ-----------------ESVATLAYQIDLPKANLVFRGGIDSNWQIFGVLEKRLAPLPFTLALSGRMNHVKNNFRLGCGLMIG---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z6L1-1", "uniprot_id": "TO402_DROME", "id": "A1Z6L1-1", "name": "Mitochondrial import receptor subunit TOM40 homolog 2", "aln": "MGNVMASTADAESSR-GRGHLSAGLRLP-EAPQY------SGGVP--PQMVEALK--AEAKKP------------ELTNPGTLEELHSRCR---DIQANTFEGAKIMVNKGLSN--HFQVTHTINMNSAGPSGYRFGATYVGTKQYGPTEAFPVLLGEIDPMGNLNANVIHQLTSRLRCKFASQFQDSKLVGTQLTGDYRGRDYTLTLTMGNPGFFTS---SGVFVCQYLQSVTKRLALGSEFAYHYGPNVPGRQVAVLSAVGRYAFG--DTVWSCTLGP-AGFHLSYYQKASDQLQIGVEVETNIRQQ-----------------ESTATVAYQIDLPKADLVFRGSLDSNWLISGVLEKRLQPLPFSLAISGRMNHQKNSFRLGCGLMIG---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23644-1", "uniprot_id": "TOM40_YEAST", "id": "P23644-1", "name": "Mitochondrial import receptor subunit TOM40", "aln": "----MSAPTPLAEASQIPTIPALSPLTAKQSKGN-----FFSSNPISSFVVDTYKQLHSHRQS-----------LELVNPGTVENLNKEVSRDVFLSQYFFTGLRADLNKAFSMNPAFQTSHTFSIGSQALPKYAFSALFANDN--------LFAQGNIDNDLSVSGRLNYGWDKKNISKVNLQISDGQPTMCQLEQDYQASDFSVNVKTLNPSFSEKGEFTGVAVASFLQSVTPQLALGLETLYSRTDG-SAPGDAGVSYLTRYVSKKQDWIFSGQLQANGALIASLWRKVAQNVEAGIETTLQAGMVPITDPLMGTPIGIQPTVEGSTTIGAKYEYRQS--VYRGTLDSNGKVACFLERKVLPT-LSVLFCGEIDHFKNDTKIGCGLQFETAGNQELLMLQQGLDADGNPLQALPQL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. . . .. . . * ****.*: : . : : * : :**.:* **..**. :.. . * *. :.. : . *::* .:...: : .*. * .: : . * :*:. *:: :. **.. :*: * :***:: *.** * * . : * :*. . : : : .. ::*. :::: * * . : .:.. : : :: :::* ::** : **::: * ::: : . ::* **. * *: : ", "identical_positions": 51, "similar_positions": 108, "identity": "12.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1368", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VP51-1", "uniprot_id": "Q9VP51_DROME", "id": "Q9VP51-1", "name": "AB hydrolase-1 domain-containing protein", "aln": "MDTDDNSSGTITGSDLGQRYRHAGDLTGEAPTRPRANIWCSKKYFAEISITVPWGHISGKWYGPQNVQPILGLHGWQDNAGTFDRLMPLLSPDVAFLAIDLPGHGLSSRLPDGCYYNSVDN-LYVIRLIMKQYKWEKVSLVGHSMSSIICFVFAAVFPDKVDMIIGID--ALKPHQRPYPSVIRTMETRLDEFLREDERNRSK--NEPPSYTYDELIERVYIGTFHSVNKEHCKHLMARNIGKSEKYPDKYFFCRDRRLKFYNYAIGSQELCVEMANRIT-CPYLFIKAAQSSYFEDKK--------YYDEVLDVLLK-KPNFEYLEVNG-SHHVHMNDPEAIIAPVNNFIQRFGPAAAAASRQKAKEA--------------------KESKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VP50-1", "uniprot_id": "Q9VP50_DROME", "id": "Q9VP50-1", "name": "AB hydrolase-1 domain-containing protein", "aln": "MKVS-------RGLFLLKQLPNVRNSS-SGPTKP---FKILNKHFDEISIPVPWGHISGKWYGPKHVRPIVGMHGWQDNAGTFDTLAPLLPSHLSFLSIDAPGHGLSSWLPPGTSYHSIDL-VLITRRLMEEYNWDKISILAHSMSSINGFVFSALFPDKVDLFVGLD--VLKPPVRSARGIVDSLTERIESALKLERRLKSG--SEPPAYDWDQLVTRLHEGSNKSVSIDACKYLLQRNCKPSTHEPHKYYFSRDNRLKSSLFYTLHQEVPMEMARRIK-CPHLFIKALQAPYYERKE--------YFDEVLAELQK-NPLFEYHEVEG-THHVHLNEPEKVAPIINSFINRYRPL-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W047-1", "uniprot_id": "Q9W047_DROME", "id": "Q9W047-1", "name": "AB hydrolase-1 domain-containing protein", "aln": "------------------------------------MGTLSLSDFEAVKIPVPWGHISGRWYGNRNERPILAIHGWLDNLGTFDRLIPLLPDYLGVLCIDLPGHGRSSHLPPGMYYSVYEY-VFTIPLVMKEYGWSKVSLIGHSLGGVLSFIYASLAPHTVDMIVSLD--ILLPLRND----IDYMDLSIEKQLVNVERQKLGNYIEPPSYTHNQLGKVLAAGSFNSVSPELAKHLLHRQLAKSKLYPERFYFTRDIRVKYYHYIDIDDSLGAEMARRIIKKPYLIIKGSLSPYLSVR----------NNEAISILAKDNPHFEFYEVENGTHHLHLHAAEECAGYIVPFIQHHRPPAMTSWTVAGKE------DRSRKPKRFFTWTNKKRSKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W048-1", "uniprot_id": "Q9W048_DROME", "id": "Q9W048-1", "name": "AB hydrolase-1 domain-containing protein", "aln": "---------------------------------------MSLSDFKEVRIPAPWGHISGRWYGNRTERPILAIHGWLDNLGTFDRLIPLLPDYIGVLCIDLPGHGRSAHIQPGMHYAVNDY-VLIIPRVMKEYGWSKVSLMGHSLGGIISFVYTSLAPDTVDMVISLD--ILLPLSKDPKTVIKYLNHSLDKHLVEEERQVEGNLHEPPSYTLAQLTQVLAKGSDNSVTPEFAQHLLHRQVSKSQLYPDRFFFSRDGRVKYYSHLQMEPEFGEALVKRIRRIPCLIIKGSKSDFVEAR----------TEKAVAILRQNNPHFEFYEVEGGTHHVHLHAAEECARYIVPFIRHHRPPALTSWSLSGKEEHLSAEEKRRQQERFFKRSTHAKSKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W045-1", "uniprot_id": "Q9W045_DROME", "id": "Q9W045-1", "name": "AB hydrolase-1 domain-containing protein", "aln": "--------------------------------------MHKRLQYEEVMIPAPWGHIAGRWYGNRADRPILAIHGWLDNLGTFDRLIPLLPDYIGVLCIDLPGHGRSSRLPPGVPYNVYDY-VFIIPRVMKEFGWSKVSLMGHSLGGVMSFMYAAMAPSTVDMIISLD--VLLPRRIED---PSKLTKDIEGYLLEERRQADGTEHEPPSFTLSKLRETLARNSNNSVPQHLADHMLHRQVAKSNMYPEKVFFSRDGRVKFYHIFDIENGLALEMARRIEKKPYLVIKGSLSPFVGPR----------CNETMSILSHDNPNFEFYEVEGGKHHVHLHAAEECARYIVPFIRNHRPP--------------------------------RSSKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O18391-1", "uniprot_id": "KRAK_DROME", "id": "O18391-1", "name": "Probable serine hydrolase", "aln": "------MGQTRVAATTAAQSPAAELSPETNGQTEEPLQLLGEDSWEEFSIAVPWGTVEAKWWGSKERQPIIALHGWQDNCGSFDRLCPLLPADTSILAIDLPGHGKSSHYPMGMQYFIFWDGICLIRRIVRKYNWKNVTLLGHSLGGALTFMYAASFPTEVEKLINID--IAGPTVRGTQRMAEGTGRALDKFLDYETLPESK----QPCYSYDEMIKLVLDAYDGSVDEPSVRVLMNRGMRHNP-SKNGYLFARDLRLKVSLLGMFTAEQTLAYARQIR-CRVLNIRGIPGMKFETPQ--------VYADVIATLRENAAKVVYVEVPG-THHLHLVTPDRVAPHIIRFLKEA----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9NQF3-1", "uniprot_id": "SERHL_HUMAN", "id": "Q9NQF3-1", "name": "Serine hydrolase-like protein", "aln": "-----------------------------------MAENAAPGLISELKLAVPWGHIAAKAWGSLQGPPVLCLHGWLDNASSFDRLIPLLPQDFYYVAMDFGGHGLSSHYSPGVPYYLQTF-VSEIRRVVAALKWNRFSILGHSFGGVVGGMFFCTFPEMVDKLILLDTPLFLLESDEMENLLTYKRRAIEHVLQVE-ASQE----PSHVFSLKQLLQRQRT-ALTSSAGSC---------------------------------------------------------------------------------------------VRIPS-GSCRPMS---------------C----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9H4I8-1", "uniprot_id": "SEHL2_HUMAN", "id": "Q9H4I8-1", "name": "Serine hydrolase-like protein 2", "aln": "-----------------------------------MSENAAPGLISELKLAVPWGHIAAKAWGSLQGPPVLCLHGWLDNASSFDRLIPLLPQDFYYVAMDFGGHGLSSHYSPGVPYYLQTF-VSEIRRVVAALKWNRFSILGHSFGGVVGGMFFCTFPEMVDKLILLDTPLFLLESDEMENLLTYKRRAIEHVLQVE-ASQE----PSHVFSLKQLLQRLLK-SNSHLSEECGELLLQRGT---TKVATGLVLNRDQRLAWAENSIDFISRELCAHSIRKLQAHVLLIKAVHGYFDSRQ-NYSEKESLSFMIDTMKSTLKEQFQFVEVPG-NHCVHMSEPQHVASIISSFLQ-CTHMLPAQL--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A071-1", "uniprot_id": "D4A071_RAT", "id": "D4A071-1", "name": "", "aln": "-----------------------MLPLAYSSRWSRHSSPSPLGLLSELKLAVPWGHIAVKVWGLQKNPPVLCLHGWLDNANSFDKLIPFLPKDFCYVAMDFGGHGLSTHYSPGLPYYHHNF-VSEVRRVVSAFKWTRLSLLGHSFGGVVGGLFACMFPEMVDKLILLDSTPLLMDLNEVENIMTYRRKNIEQTLKVE-DSQK----PPGIFSPEEMLHELLT-KNSHLNEDCGELLLQRGT---TKVAEGLVLNRDQRLSWPQYSFDFMGKELTMHSLRRLQASVLIIKALDGYYDVRRENDLNKASFLLMLDILRSTLKERFQFVEIPG-NHYIHMNKPQIVADIIRSFLQGPPRTTPSRL--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPB5-1", "uniprot_id": "SERHL_MOUSE", "id": "Q9EPB5-1", "name": "Serine hydrolase-like protein", "aln": "-----------------------------------------MGLHSELKLAVPWGHIALKVWGSQKNPPVLCLHGWLDNANSFDRLIPLLPQDFCYMAMDFGGHGLSSHYNPGLPYYQQNF-VSEVRRVATAFKWNQFTLLGHSFGGCVGGTFACMFPEMVDKLILLDSTPFFLDSNEMENILTYRRRNIEHTLQVE-ASQKK---SLRAVSPEEMLQGFLN-NNSHLDKDCGELILQRGT---TKVDAGLVLNRDRRISWPENSFDFVSKEMFVHSAKSLQASVLMIKALQGYYDVRRANDADKAPMHFMVDTLRSTLKERFQFVEVPG-NHYIHMNKPQVVAGVVGPFLQGLQRMTSARL--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2BGU9-1", "uniprot_id": "SERHL_DANRE", "id": "A2BGU9-1", "name": "Serine hydrolase-like protein", "aln": "-------------------------MLPAFMSLRHFTTTTMRRAASEFRMPVPWGELRGQVWGPSHGRPVLCLHGWADNSGTFNTLVPLLPNDWRFVAIDFPGHGLSSHRPDGCFYAFPFY-VADVRRVVEALQWKRFSIIGHSMGGNVAGMFSALYPEMVESVVLLDTYGFLP--TEVTDMFTNMRKGINDQIQYDNMANER---KERVYTYEKAKERLKV-ANPYLSDQSADILLERAV---REVDGGFVFTRDFRIN--LKNIIYINIDQCLHVLSQVKAKVMLLLAKDGLFKTFTLPDG------YADRICKSWTDQKATFVEVEG-DHHVHLNNPEAVSSVITDFLQPQSPDQTESQSGNQTSRL------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :..*** : : :* *:: :*** ** .:*: * *:*. :.:* *** *: * * : : * ..:::.**:.. : . * *: .: :* :: : : .: . : ", "identical_positions": 27, "similar_positions": 44, "identity": "6.85%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1393", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D3E6-1", "uniprot_id": "STAG1_MOUSE", "id": "Q9D3E6-1", "name": "Cohesin subunit SA-1", "aln": "--------------------------------MITSELP-VLQDSTN--------ETTAHSDAGSELEETEV-KGKRKRGRPGRPPSTNK----------KPRKSPGEKSRIEAGIRGAGRGRANGHPQQNGDG---------DPVTLFEVVKLGKSAMQSVVDDWIELYKQDRDIALLDLINFFIQCSGCRGTVR-IEMFRNMQNAEIIRKMTEEFDEDSGDYPLTMPGPQWKKFR--------SNFCEFIGVLIRQC-QYSIIYDEY-----------MMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIHQDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNSIFKGIFVHRYRDAIAEIRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTLHDRQGEVRLKCLKALQSLYTNRELFPKLELFTNRFKDRIVSMTLDKEYDVAVEAIRLVTLILHGSEEALSNEDCENVYHLVYSAHRPVAVAAGEFLHKKLFSRHDPQAEEALAKRRGRNSPNGNLIRMLVLFFLESELHEHAAYLVDSLWESSQELLKDWECMTELLLEEPVQGEEAMSDRQESALIELMVCTIRQAAEAHPPVGRGTG-KRVLTAKERKTQIDDRNKLTEHFIITLPMLLSKYSADAEKVANLLQIPQYFDLEIYSTGRMEKHLDALLKQIKFVVEKHVES-DVLEACSKTYSILCSEEYTIQNRVDIARSQLIDEFVDRFNHSVED---LLQEGEEADDDDIYNVLSTLKRLTSFHNAHDLTKWDLFGNCYRLLKTGIEH------GAMPEQIVVQALQCSHYSILWQLVKITDGSPSK----EDLLVLRKTVKSFLAVCQQCLSN-VNTPVKEQAFMLLCDLLMIFSHQLMTGGREGLQPLVFNPDTGLQSELLSFVMDHVFIDQDEENQSMEGDEEDEANKIEALHKRRNLLAAFSKLIIYDIVDMHAAADIFK--HYMKYYNDYGDIIKETLSKTRQIDKIQCAKTLILSLQQLFNELVQE----QGPNLDRTSAHVSGIKELARRFALTFGLDQIKTREAVATLHKDGIEFAFKYQNQKGQEYPPPNLAFLEVLSEFSSKLLRQDKKTVHSYLEKFLTEQMMERREDVWLPLISYRNSLVTGGEDDRMSVNSGSSS-SKTSSVRSKKGRPPLHRKRVEDESLDNTWLNRTDTMIQTPGPLPTPQLTSTVLRENSRPMGEQIQEPES-EHGSEPDFLHNPQMQISWLGQPKLEDLNRKDRTGMNYMKVR-AGVRHAVRGLMEEDAEPIFEDVMMSSRSQLEDMNEEFEDTMVIDLPPSRNRRERAELRPDFFDSAAIIEDDSGFGMPMF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WVM7-1", "uniprot_id": "STAG1_HUMAN", "id": "Q8WVM7-1", "name": "Cohesin subunit SA-1", "aln": "--------------------------------MITSELP-VLQDSTN--------ETTAHSDAGSELEETEV-KGKRKRGRPGRPPSTNK----------KPRKSPGEKSRIEAGIRGAGRGRANGHPQQNGEG---------EPVTLFEVVKLGKSAMQSVVDDWIESYKQDRDIALLDLINFFIQCSGCRGTVR-IEMFRNMQNAEIIRKMTEEFDEDSGDYPLTMPGPQWKKFR--------SNFCEFIGVLIRQC-QYSIIYDEY-----------MMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIHQDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNSIFKGIFVHRYRDAIAEIRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTLHDRQGEVRLKCLKALQSLYTNRELFPKLELFTNRFKDRIVSMTLDKEYDVAVEAIRLVTLILHGSEEALSNEDCENVYHLVYSAHRPVAVAAGEFLHKKLFSRHDPQAEEALAKRRGRNSPNGNLIRMLVLFFLESELHEHAAYLVDSLWESSQELLKDWECMTELLLEEPVQGEEAMSDRQESALIELMVCTIRQAAEAHPPVGRGTG-KRVLTAKERKTQIDDRNKLTEHFIITLPMLLSKYSADAEKVANLLQIPQYFDLEIYSTGRMEKHLDALLKQIKFVVEKHVES-DVLEACSKTYSILCSEEYTIQNRVDIARSQLIDEFVDRFNHSVED---LLQEGEEADDDDIYNVLSTLKRLTSFHNAHDLTKWDLFGNCYRLLKTGIEH------GAMPEQIVVQALQCSHYSILWQLVKITDGSPSK----EDLLVLRKTVKSFLAVCQQCLSN-VNTPVKEQAFMLLCDLLMIFSHQLMTGGREGLQPLVFNPDTGLQSELLSFVMDHVFIDQDEENQSMEGDEEDEANKIEALHKRRNLLAAFSKLIIYDIVDMHAAADIFK--HYMKYYNDYGDIIKETLSKTRQIDKIQCAKTLILSLQQLFNELVQE----QGPNLDRTSAHVSGIKELARRFALTFGLDQIKTREAVATLHKDGIEFAFKYQNQKGQEYPPPNLAFLEVLSEFSSKLLRQDKKTVHSYLEKFLTEQMMERREDVWLPLISYRNSLVTGGEDDRMSVNSGSSS-SKTSSVRNKKGRPPLHKKRVEDESLDNTWLNRTDTMIQTPGPLPAPQLTSTVLRENSRPMGDQIQEPES-EHGSEPDFLHNPQMQISWLGQPKLEDLNRKDRTGMNYMKVR-TGVRHAVRGLMEEDAEPIFEDVMMSSRSQLEDMNEEFEDTMVIDLPPSRNRRERAELRPDFFDSAAIIEDDSGFGMPMF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6ADB5-1", "uniprot_id": "A0A8I6ADB5_RAT", "id": "A0A8I6ADB5-1", "name": "Cohesin subunit SA", "aln": "--------------------------------MITSKVGNIILDSTN--------ETTAHSDAGSELEETEV-KGKRKRGRPGRPPSTNK----------KPRKSPGEKSRIEAGIRGVGRGRANGHPQQNGEG---------DPVTLFEVVKLGKSAMQSVVDDWIESYKQDRDIALLDLINFFIQCSGCRGTVR-IEMFRNMQNAEIIRKMTEEFDEDSGDYPLTMPGPQWKKFR--------SNFCEFIGVLIRQC-QYSIIYDEY-----------MMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIHQDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNSIFKGIFVHRYRDAIAEIRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTLHDRQGEVRLKCLKALQSLYTNRELFPKLELFTNRFKDRIVSMTLDKEYDVAVEAIRLVTLILHGSEEALSNEDCENVYHLVYSAHRPVAVAAGEFLHKKLFSRHDPQAEEALAKRRGRNSPNGNLIRMLVLFFLESELHEHAAYLVDSLWESSQELLKDWECMTELLLEEPVQGEEAMSDRQESALIELMVCTIRQAAEAHPPVGRGTG-KRVLTAKERKTQIDDRNKLTEHFIITLPMLLSKYSADAEKVANLLQIPQYFDLEIYSTGRMEKHLDALLKQIKFVVEKHVES-DVLEACSKTYSILCSEEYTIQNRVDIARSQLIDEFVDRFNHSVED---LLQEGEEADDDDIYNVLSTLKRLTSFHNAHDLTKWDLFGNCYRLLKTGIEH------GAMPEQIVVQALQCSHYSILWQLVKITDGSPSK----EDLLVLRKTVKSFLAVCQQCLSN-VNTPVKEQAFMLLCDLLMIFSHQLMTGGREGLQPLVFNPDTGLQSELLSFVMDHVFIDQDEENQSMEGDEEDEANKIEALHKRRNLLAAFSKLIIYDIVDMHAAADIFK--HYMKYYNDYGDIIKETLSKTRQIDKIQCAKTLILSLQQLFNELVQE----QGPNLDRTSAHVSGIKELARRFALTFGLDQIKTREAVATLHKDGIEFAFKYQNQKGQEYPPPNLAFLEVLSEFSSKLLRQDKKTVHSYLEKFLTEQMMERREDVWLPLISYRNSLVTGGEDDRMSVNSGSSS-SKTSSVRSKKGRPPLHRKRAEDESLDNTWLNRTDTMIQTPGPLPTPQLTSTVLRENSRPMGEQIQEPES-EHGSEPDFLHNPQMQISWLGQPKLEDLNRKDRTGMNYMKVR-AGVRHAVRGLMEEDAEPIFEDVMMSSRSQLEDMNEEFEDTMVIDLPPSRNRRERAELRPDFFDSAAIIEDDSGFGMPMF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ACD6B6N8-1", "uniprot_id": "A0ACD6B6N8_DANRE", "id": "A0ACD6B6N8-1", "name": "Cohesin subunit SA", "aln": "--------------------------------MINSDFP-VLQDSSND----GQGDTISLAISVSELDDPEVGKGKKKRGRPGKQGAANK----------KARRSPVDK----------GGRRPNGVAHQNGEGT--------DPSTLFEVVKQGKSAMQSVIDDWIESYKQDRDLALLDLINFFIHCSGCKGTVR-IEMFRNMQNAEIIRKMTEEFDEDSGDYPLTMTGPQWKKFR--------YNFCEFIMVLIRQC-QYSIIYDEY-----------MMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINQDNTQRQYEAERNKVAGKRANEKLELLLEKRKELQENQDEIENMMNSIFKGIFVHRYRDAIAEIRAICIEEIGVWMKLYSDAFLNDSYLKYVGWTLHDRQGEVRLKCLKALQTLYTNRELYPKLELFTNRFKDRIVSMTLDKEYDVAVEAIRLVTLILHGSEDALSNEDCENVYHLVYSAHRPVAVAAGEFLHRKLFSRHDPQAEEALAKRRGRNSPNGNLIKMLVLFFLESELHEHAAYLVDSLWDSSHDLLKDWDCMVELLLEDPVQGEEVLGDRHESALIELMVCTIRQAAEAHPPVGRGTG-KRVLTAKEKKTQIDDKNRLTEHLIVALPMLLSKYQVDAEKVANLLQIPQYFDLEVYSSGRMEKHLDALLKQIRVVVEKHAEM-EVLEACSKTYSILCSEEYTIMNRVDIARSQLIDELTDKFAHSVED---LLQEGEEADDDDIYNVLSTLKKLTAFHNAHDLTKWDLFKNCYRLLKMGIEQ------GSMPEQIAVQALQCSHYSILWQLVKITEGCPSK----DDLLALRRVVKSFLAVCQQCLSN-VNTPVKEQAFMLLCDLLMIFSHQLVSGGREGLQPLVFNPDGSLQNELLNFVLDHVFIDQDDENQSMEGDEEDEANKIEALHKRRNLLAAFCKLIIYDIVDMPAAADIFK--QYMKYYNDYGDIIKETLSKTRQMDKIQCAKTLILSLQQLFNELIQD----QGPNLDRTSSHVSGIKELARRFALTFGLDQIKTREAVATLHKDGIEFAFKVPNPKGPEYPPPNLAFLEVLCEFSSKLLRQDKKTVHSYLEKFMTEYMMERREDVWLPLIAYRNSLLTGGDDDRLSVTTGASSTSKASTVRSKRGRPPQHKRRPDEESVEGSWVMRNDT-LQTPGGLHTPQLTSTVLRENPRQAADHIPDQDSSEPGSEPDYMHNPQMQMSWLDQQKMEEVNRKERSGMNYMKSRSAGVRQQVRGLMEDDAEPIFEDVMMSSRGQLEDMNEEFEDTMVIDLPASRNRRERAELRPDFFDSTAIMEDDPGFGMQMF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VM62-1", "uniprot_id": "Q9VM62_DROME", "id": "Q9VM62-1", "name": "", "aln": "-------------------------------MMARRGGKRIRMDDPPPDYEELHSDALNESTSDADSPTKRMTRLRARGGVRDKPPIIDDDEDDFFAPIARKRKTPATRKGPTERKERVERPRKEPVDKGHHERIDSEREITTDENSLYYIVRHSKNPIASIVDQWIEQYKANRETALVALMQFFINASGCKGKIS-EDIQYPVDHTSIIRRMTEEFDEESGEYPLIMSGTQWRKFK--------NNFCDFVQTLVKQC-QYSIIYDQF-----------LMDNVISLLTGLSDSQVRAFRHTATLAAMKLMTALVDVALLVSNNFDNAAKQFEAERVKSRDRRASDRLDSLMTKRSELEENMDEIKSMLTYMFKSVFVHRYRDSLPDIRAICMAEIGIWMENYPQNFLDDSYLKYIGWTLHDKIGEVRLRCLQSLLPLYEKDELKGKLELFTSKFKDRIVAMTLDKEFEVSVHAVKLVISILKIHPEILADKDCEIVYELVYSSHRGVAQAAAEFLNVRLFH-LTADMEETKTKRGKVRMPNTPLVRDLVQFFIESELHEHGAYLVDSFIDSN-DMVRDWECMTDLLLEEPGPNEEVLDNKQESTLIEIMVSSVKQSATGEVPVGRASNRKCTLSAKELKAIQDEKAKLTEHFIVTLPSLLEKYQADSEKLANLLAVPQYFDLNLYTTNRQEGNLQALLDRINQVMSMHTGR-EVLETCAKTLECLCAEGSATYTRCNIARSNIIESAVNKYKDAIEEWRNLIQGEETPNEDDIYNITITLKVLSILYSSHNLNPWELFKSLFQDVEEAQSKENI--DRCLPNEALVYCIEACYFSISWGLQYVENECESVN-VTEVVAELRNNLDTFMGACFELTRDGPTVQIQEAAYQSICDLLIIFSDKLARSEIEHIRGLEYKSRMDEHLILDNFVQHYVFS--------LKQDVAQDETRIEELHKKRNFLACYCKLVVYNIIPTMRAASIFK--YYVKCYNDYGDIIKATLGKAREINKVNFAMTLLLSLITVFKSLQEQS---EDGIVSKSSQEFVDLKELAKRFALTFGFDAIKNRESVAAIHRGGIYFAANKE-PDDPVRAPTRLLFLEVLNEFNYKLLKQDKKVIMSFLDKIIPPAMPSSRAEEWQPLILYRNSLLHG-ETDQAPVAS------KRAYTR---------KRRDHDEEEE---------------------------------------EEEDEEEHNDPDYRG---------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0F4-1", "uniprot_id": "Q9W0F4_DROME", "id": "Q9W0F4-1", "name": "", "aln": "--------------------------------MSDIS-----------------FDDAVLNDSQASNQMDFEIREECSIAPNDEPVCVDG--------------TVGDATNKSLLQMILSRKRLSPTNKR-------------------------NSHIESVAKYWGEFYLDSPTAALVALLQFVVEVSGSHYQIP-DDTSMPFSYSDILSNSSSHFSN-THIYPLIR--KPADVFV--------NQVGSFLNALLLVANKFRSDSYQL-----------FLVQLTNFVMACSESNIRTFRHTATMIGLKIMTILSDLKS----------------------------------------LDDEIAMTVWMQMFNSMFVARSRDIVTDIRLLCISELGQWFARYPHCHLQPTSLRIFYEALNDGSGDVIQCSLDNISVLCRKDVLFSEIVALTSEFREILVELCLGKEDAIAEKSVQFLTHFHVLSAEILTDDVCRVLEQLIMAANRGLAQAAADLFILRRNGLDGETFCQR--------------VKHLLQLFIECG-HEQADYLVDSLIDNC-ELVLDWKSMIAVLLENPKSRE--LSDIHCSSLIAILLAGVKQATAGEIPPGRYTK------DLKREPRQGAQERATKCLAPVLPELLRTYANRLQDIERLLELPKYFCFDYYHEQNRMGQLNELVEHFELIIFDQTSSTTVLQITVKTLEFLNRMIPIPLT------KQLLNSAVTNYKMAWHR--TQDTSPSRSTHNESNRLLATLRLLTVLSGHFNLSKWDLTEPLLFSLKMLLRQRRLPNGDDLPPEAFSLYLKACFCCLCWDMENLEGTALNNVDMDEYCDVLHHNLEDYLYVTFSLVGKSNTEPLAYPCFSYTCDLFVLHG-NLCGSSNPSIRSVAHVPSGNELDILEGFLMEHFLE--------LSPSDLMLETNSDQLQRIRSILTSYLKVVCLGVVPTMRASKFYE--YYVKYHAPFGDVMRCSMELALQRNPIHFAMTMLHTCLLLYAKVFPDDTRHAAGQRALRPAEFSELMELANRLAKILISNPMEHRECVIALHRSGILFVFELA-QKQPTEATKKLPFLRVLKVFVPLLLVQDKTRILNFFEPYEQLIIPTCNRNDIAHLKEYRNALRPRKTKSYPQAT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40541-1", "uniprot_id": "SCC3_YEAST", "id": "P40541-1", "name": "Cohesin subunit SCC3", "aln": "MTAVRRSTRIRTKSQVIEEDYDDEQNTSAQHVESDKITAKTQHEEEEEQDTGESEESSSEDDYEDQDDDDYVDTATAKRKSRKRKPKSAS----------NTSSKRQKKKPTSAQKSAVSHAPAYHRSKKDQDQYLEIAKDFQPTELFDILSTSEDVSIEELLREWLETYSENRDKFLQEFINLLLNCCGSVARVEDHDVHSNESSNETIGEIQLLFQRQKLHEFYLLISKENKKRKNFKMGPLYQNFAEFMTKLLEVANDLQLLYVESDEDDTQIVTGNLVLDLLTWLSSFSVCKIRCFRYISTLTLYLFQDYLTQQAVNLEKNYLAKLSKQLSLEEK-KKRPNNKTLEKLESTIAETQGSKVVIDSIIDNIVKLCFVHRYKDVSDLIRSESMLHLSIWIKNYPEYFLKVTFLKYFGWLLSDNSVSVRLQVTKILPHLIIQN---HNSKSTDNSAIRQVFERFKTKILEVAIRDVNLDVRIHSIQVLTEASS-------LGYLDDSEILIISSLMFDEEFDPFKTSSFNKR----------------SKFLSTVAKFLARVIKEKFDEFIKTHEDLPKEVDGLEVGPVVQVGIFIKILNDSLIYHLKDCAEVDSRTKIRMLTQAAEFLS-PYISTHLKTICNLLISDTESNELIQKLQNSANNNSDDEDVDDEELDITPLFPIDRNSTILYLNVFHGLCAGANNPKIQTKDS---------VKEIVLPLFYDLLNAASIESADILCPLLESFITFSLD--DWISIGYETELKKITDKTIKAFMDSTIGNSKVDMKYDIFAKFIHHIHHFEKK-------ELQEKFLNQIATLKIHLKKFLQEKMDPN------------NSRDDYKDLTCSLYELYINKLTILGRDYPIEVDEELLQLFLNNFVSRIPIMFQDFDDSTAQEINFKMLVLLATWNLEKWREIIEKVRDYENSISKDLRSVWKPIAAIIGRLNTLVISLAATNETFENINSLFYLKWSACTSLMDIIVAIKIFELKLPADATTWRYSMSEQFPFYLHDN------ASKVLLKIFLYLESLFAKQVDVQLERVADEDANLNDLPETGFFENIETEFLLFTVKLKG-LMKLNILDERFASRVALNKEKLGPLFKKIVDDTIMENPEPNKKNIQKAKSNQTQREKAPLQPNSERETDHANTENNDPDIPMTIDLEPIEESSQNNS-------------------------------ELAPIEEHPTVVDAIDNSDEITQD-------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . : . : .: * * * . * ::::.:. .*. : : . . : . *.. . :. .*: *: . . : :: : . : . * .::* **: :*: : * : . .: :.: ** * :* ** .: .:. *: *.. .*. : *: . * * .* . : * : : . :. * :: . :.: : :.. * . : :. :: . : . : . .*.: .. :: : . : : : :.: * : .. : :: : * . : . * :. * :: :. * . . . : . ::: : . .. . : : . ::: :. : : : : : : . . . . :*: :. :: :: . . : :: : : . : : : : : .: : . : *:* . : : . * * : : : . : .* : . . : : . *: : * *.:* : :* : :. : : :. ", "identical_positions": 47, "similar_positions": 217, "identity": "3.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1411", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P00747-1", "uniprot_id": "PLMN_HUMAN", "id": "P00747-1", "name": "Plasminogen", "aln": "MEHKEVVLLLLLFLKSG-------QGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFTCRAFQYHSKEQQCVIMAENRKSSIIIRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILECEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKKCS-----------GTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYCDVPQCAAP-SFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFG-MHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPTRKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20918-1", "uniprot_id": "PLMN_MOUSE", "id": "P20918-1", "name": "Plasminogen", "aln": "MDHKEVILLFLLLLKPG-------QGDSLDGYISTQGASLFSLTKKQLAAGGVSDCLAKCEGETDFVCRSFQYHSKEQQCVIMAENSKTSSIIRMRDVILFEKRVYLSECKTGIGNGYRGTMSRTKSGVACQKWGATFPHVPNYSPSTHPNEGLEENYCRNPDNDEQGPWCYTTDPDKRYDYCNIPECEEECMYCSGEKYEGKISKTMSGLDCQAWDSQSPHAHGYIPAKFPSKNLKMNYCRNPDGEPRPWCFTTDPTKRWEYCDIPRCTTPPPPPSPTYQCLKGRGENYRGTVSVTVSGKTCQRWSEQTPHRHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSQLRWEYCEIPSCESSASPDQSDSSVPPEEQTPVVQECYQSDGQSYRGTSSTTITGKKCQSWAAMFPHRHSKTPENFPDAGLEMNYCRNPDGDKGPWCYTTDPSVRWEYCNLKRCS-----------ETGGSVVELPTVSQEPSGPSDSETDCMYGNGKDYRGKTAVTAAGTPCQGWAAQEPHRHSIFTPQTNPRAGLEKNYCRNPDGDVNGPWCYTTNPRKLYDYCDIPLCASASSFECGKPQVEPKKCPGRVVGGCVANPHSWPWQISLRTRFTGQHFCGGTLIAPEWVLTAAHCLEKSSRPEFYKVILGAHEEYIRGLDVQEISVAKLILEPNNRDIALLKLSRPATITDKVIPACLPSPNYMVADRTICYITGWGETQGTFGAGRLKEAQLPVIENKVCNRVEYLNNRVKSTELCAGQLAGGVDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVDWIEREMRNN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1Q890-1", "uniprot_id": "F1Q890_DANRE", "id": "F1Q890-1", "name": "Plasminogen", "aln": "MEVHKAVLLLGLFLFTGFLRSHSQSTDVLEAYIKTDGAWIVKLPKSQYTVNTVEECAVKCNKEVSFTCRSFLYIEKDQDCVTLPANSKTDQILRRMSAALYEKKEYLLECVNGIGMDYRGTKSKTKSGKTCQRWEGTFPHVPNITPRAYPKADLESNFCRNPDGDKGGPWCYTTDPEKRWEHCNIQDCTEECMQCSGENYRGKISTTVSGFTCQRWDSQQPQNHGYLPSALPDKYLEENYCRNPDGEPRPWCFTTSPSKRWEACAIPRCTTEPPTIVPELTCASGEGSSYRGTISVTITGKTCQQWTSQSPHKHSRSPENYPCKGLDGNYCRNPDNERSPWCYTTDPETRWEYCSVPSCGDQPRPEEP--------VIPQGEECYEGDGSSYRGVMSETISGKKCQFWTSMEPHRHSKTPQNFPKADLRRNLCRNPDGDRAPWCYTTDPTVRWEYCNIERCDNRPNIQEPPAKPAATTPTQSTPAQSTPDQSAPSEKDCKNGNGAEYRGSTSMTVMGVTCQAWRSMTPHQHASFTPETHPDKGLESNQCRNPDSDVNGPWCYTTDPSKKWDYCQIPDCESL---KCGQPATKPKRCFGRIVGGCVSKPHSWPWQISLRTRGK-IHFCGGTLIDPQWVVTAAHCLERSDSPSAYKIMLGIHTERATESSKQERDVTKIIKGPAGTDIALLKLDRPALINDKVSPVCLPEKDYIVPSNTECYVTGWGETQDTGGEGYLKETGFPVIENKVCNRPSFLNGRVKDHEMCAGNIEGGNDSCQGDSGGPLVCYAQNTFVLQGVTSWGLGCANAMKPGVYTRVSKFVDWIERSIKEN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ::.:**: *:* .* . : *: *:.*:** :..:.*.* .. :.:* .**: : .*.**:* * .*:*:** :. * *:. *:* .. *:**: ** ** .* * .**** *:**.* :**:* .* ** *. :* ::*. .**.*:*****.* *********:**:::*:* :* **** ****:* ****.*:**: ** ****.*: ***:*: :*.* *: ******* * *******.*.**** * ****** **. * * .* *..***.::**::*:***:*: *:** *.*:***:***.*: *******.: :***:**:.: *****.:*** ... . : * ::**..**.****. * * :***** *::* ****.***:*:*.*.* * *****.*:.***:****:*******:::*. : : . ... *. : ** ** *** ***. : *. *..** * : **:*: ***:*:* ***.* *****.**.*******:* * :***::* * : .**:* .:**:* **:*****::*******:***** ******** *:**:*******:* *. **::** * * ** .*:::: * *******. ** *.*** *.***. :*:*...* *::*******.* * * ***: :********** .:**.**:. *:***:: ** *************: ::.::************.. *****.***:** *** :::*", "identical_positions": 431, "similar_positions": 214, "identity": "51.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1414", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1T4-1", "uniprot_id": "SEPT6_MOUSE", "id": "Q9R1T4-1", "name": "Septin-6", "aln": "-----MAAADIARQVGEDCRTVPLAGHVGFDSLPDQLVNKS--------------------VSQGFCFNILCVGETGLGKSTLMDTLFNTKFE--------GEPATHTQPGVQLQSNTYDLQ-ESNVGLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIRRVLHSYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPVIAKSDAISKSELAKFKIKITSELVSNGVQIYQFPTDDE----SVSEINGTMNAHLPFAVVGSTEEVKIGNKMMR--ARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKLEEMGFKDTDPDSKPFSLQ----------------ETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQE-------------------------EKKKLEDKKKCLDEEMNAFKQRKAAAELLQSQGSQAGGSQTLKRDKEKKNNPWLCIE-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AA08-1", "uniprot_id": "A0A8I6AA08_RAT", "id": "A0A8I6AA08-1", "name": "Septin", "aln": "-----MAAADIARQVGEDCRTVPLAGHVGFDSLPDQLVNKS--------------------VSQGFCFNILCVGETGLGKSTLMDTLFNTKFE--------GEPTTHTQPGVQLRSSTYDLQ-ESNVGLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIRRVLHSYHDSRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKSDAISKSELAKFKIKITSELVSNGVQIYQFPTDDE----SVAEINGTMNAHLPFAVVGSTEEVKIGNKMMR--ARQYPWGTVQVENEAHCDFVKLREMLIRINMEDLREQTHARHYELYRRCKLEEMGFKDTDPDSKPFSLQ----------------ETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQE-------------------------EKKKLEDKKKCLDEEMNAFKQRKAAAELLQSQGSQAGGSQTLKRDKEKKNWQRSGFDAYWPADRGKYRVTM-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14141-1", "uniprot_id": "SEPT6_HUMAN", "id": "Q14141-1", "name": "Septin-6", "aln": "-----MAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKS--------------------VSQGFCFNILCVGETGLGKSTLMDTLFNTKFE--------GEPATHTQPGVQLQSNTYDLQ-ESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDE----SVAEINGTMNAHLPFAVIGSTEELKIGNKMMR--ARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQ----------------ETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQD-------------------------EKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQGSQAGGSQTLKRDKEKKNNPWLCTE-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BKJ6-1", "uniprot_id": "A0A8M2BKJ6_DANRE", "id": "A0A8M2BKJ6-1", "name": "Septin", "aln": "MQERTMAATEIARQAGEGARAVPLSGHVGFDSMPDQLVNKS--------------------VNHGFCFNILCVGETGLGKSTLMDTLFNTKFE--------GEPTQHNQPGVQLKSNTYELQ-ESNVRLKLTVVNTVGFGDQINKEDSYKSIVEFIDAQFEAYLQEELKIKRTLHSYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKSDAISKSELAKFKIKITSELVSNGVQIYQFPTDDE----TVAEINSTMNGHLPFAVVGSTEEVKIGNKMVR--ARQYPWGTVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQ----------------ETYEAKRNEFMGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQD-------------------------EKKKLEDKKKSLDDELNGFKQKKTAAELLQSQNQQPGGSATLKKDKERKNSGFL----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P54359-1", "uniprot_id": "SEPT2_DROME", "id": "P54359-1", "name": "Septin-2", "aln": "----MSVEVDFVDKKEVHLRTLKQSGHVGFDSLPDQLVNKS--------------------VQNGFVFNVMCIGETGLGKSTLMDTLFNTSFE--------STPSPHTLPSVKLKAHTYELQ-ESNVRLKLTICDTVGYGDQINKDDSFKAVVDYIDAQFENYLQEELKIKRSLVTCHDSRIHICLYFICPTGHGLKSLDLVCMKKLDSKVNIIPVIAKADTISKVELQRFKAKIIQELNANGVHIYQFPTDDE----TVAETNTSMNSHIPFAVVGSTEFIKVGNKLIR--ARQYPWGTVQVENETHCDFVKLREMLIRTNMEDMREKTHTRHYELYRQKRLEQMGFSDVDSDNKPISFQ----------------QTFEAKRSNHLAELQSKEEEVRQMFVQRVKEKEAELKESEKDLHAKFEKLKRDHAE-------------------------EKRKLEESRKALEEDYLDFQRRK-------QQLATAHHTLTLGKSKKK----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32458-1", "uniprot_id": "CDC11_YEAST", "id": "P32458-1", "name": "Cell division control protein 11", "aln": "-MSGIIDASSALRKRKHLKRGITFTVMIVGQSGSGRSTFIN----------------------------TLCGQQVVDTSTTILLP-----------------TDTSTEIDLQLREETVELEDDEGVKIQLNIIDTPGFGDSLDNSPSFEIISDYIRHQYDEILLEESRVRRNPR-FKDGRVHCCLYLINPTGHGLKEIDVEFIRQLGSLVNIIPVISKSDSLTRDELKLNKKLIMEDIDRWNLPIYNFPFDEDEISDEDYETNMYLRTLLPFAIIGSNEVYEMGGDVGTIRGRKYPWGILDVEDSSISDFVILRNALLISHLHDLKNYTHEILYERYRTEALSGESVAAESIRPNLTKLN---------------GSSSSSTTTRRNTNPFKQSNNINNDVLNPASDMHGQSTGENNETYMTREEQIRLEE--------------------------ERLKAFEERVQQELLLKRQELLQREKELREIEARLEKEAKIKQEE-------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q07657-1", "uniprot_id": "SHS1_YEAST", "id": "Q07657-1", "name": "Seventh homolog of septin 1", "aln": "MSTASTPPINLFRRKKEHKRGITYTMLLCGPAGTGKTAFANNLLETKIFPHKYQYGKSNASISSNPEVKVIAPTKVVSFNSKNGIPSYVSEFDPMRANLEPGITITSTSLELGGNKDQGKPEMNEDDTVFFNLIMTHGIGENLDDSLCSEEVMSYLEQQFDIVLAEETRIKRNPR-FEDTRVHVALYFIEPTGHGLREVDVELMKSISKYTNVLPIITRADSFTKEELTQFRKNIMFDVERYNVPIYKFEVDPEDDDLESMEENQALASLQPFAIITSDTRDSEGRYV-----REYPWGIISIDDDKISDLKVLKNVLFGSHLQEFKDTTQNLLYENYRSEKLSS-VANAEEIGPNSTKRQSNAPSLSNFASLISTGQFNSSQTLANNLRADTPRNQVSGNFKENEYEDNGEHDSAENEQEMSPVRQLGREIKQENENLIRSIKTESSPKFLNSPDLPERTKLRNISETVPYVLRHERILARQQKLEELEAQSAKELQKRIQELERKAHELKLREKLINQNKLNGSSSSINSLQQSTRSQIKKNDTYTDLASIASGRD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * : : : : ..: . . :. :. .:. . . . : . . : :.. : :.: * * *:.::.. . : : .:: *:: * ** :::* .* *:* .**:* ****.*:.:*: ::.:.. .*::*:*:::*:::: ** : * :: .: **:* * : * * : ***:: * . * : *:**** :.:::. .*: *:: *: ::.:::: *: ** ** *. . : . : . .: . . ::: . : : ..: ::: . . . *: * : . : .. ", "identical_positions": 55, "similar_positions": 138, "identity": "9.86%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1423", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DAU9-1", "uniprot_id": "ZN654_MOUSE", "id": "Q9DAU9-1", "name": "Zinc finger protein 654", "aln": "MAEEESDQEAERLGEELVAIVESPPGPVGLLAAGDGRGGAGGGGCGGGVGISSRDYCRRFCQVVEDYAGRWQVPLPQLQVLQTALCCFTSASASFPDECEHVQYVLSSLAVSFFELLLFFGRDEFYEEPLKDILGSFQECQNHLRRYGNVNLELVTRIIKDGGPWEDPVLQAVLKAQPASQEIVNKYLSSENPLFFELRARYLIACERIPEAMALIKSCINHPEISKDLYFHQALFTCLFMSPVEDQLFREHLLKTDCKSGIDIICNTEKEGKTLLALQLCESFLIPQLQNGDMYYIWELIFLWSKLQLKSNPSKQVFVDQCYQLLRTATNVRVIFPFMKIIKDEVEEEGLQICVEICGCALQLDLHDDPETKCLIYKTIAHFLPNDLEIVRVCALSVFFLERSLDAYHTVEELYRRPDEEYSEGMSTVQNRVRFELLPILKKGLFFDPEFWNFVMIKKNCVALLRDKSAVKLLNENTLEN------------------------------------------------------------------------PSSSLKKRVDQQSVEE---------------------------------DQSTGETDPDDASVVQPKGQ----------------------------------VNVKRSLSALNTSKVDHSVPRHRCMLCNKEFLG-----------GHIVRHAQAHQKKGSFACVICG----RKFRNRGLMQKHLKNHVKKIQRQQIATAQQDDPE-----VITLEEINGSKSLISFENGNSNTKGLEIETLTASSERNKEVIREHMAEFIKIPIA-------------------IPENAIENIIENGKPDASFNNISESLPQCDDDYEEEENED-DY-EDDYDLNQETSVLHKINGTVCHPKDVYATDQEGNFKCPALGCVRIFKR----IGFLNMHARTVHPTDLNVRQTVMKWSK-------------------------GKCKFCQRQFED----SQHFIDHLNRHSYPN---------------------------------------VYFCLHFNCNESFKLPFQLAQHTKSHRIFQAQCSFPECHELFEDLPLLYEHEAQHYLSKTPESSAQ--------------------------LSEVVPN--------HQEIDPFSNENQTIHHPVSTSKSRKYSTEPKTYIDTMEKKTDSLVHNGNEHSDDTVSN-----------------------ISLIDQKMPAIEPNPENTHSTTDLVNGHSEIEQTPLVTSDPTLKIDINRNRTENGSILPSVES-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QEHSALSVSQAPSKPNLTSEQTSYGLIVT-KPFVRPLPPSYLDERYLSMPKRRKFLTDIVDACSDQDNMYKKPVKRLRCGKCLTTYCNAEALEAHLAQKKCQTLFGFDSDDESA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IZM8-1", "uniprot_id": "ZN654_HUMAN", "id": "Q8IZM8-1", "name": "Zinc finger protein 654", "aln": "MAEEESDQEAERLGEELVAIVESPLGPVGLRAAGDGRGGAGSGNCGGGVGISSRDYCRRFCQVVEDYAGRWQVPLPQLQVLQTALCCFTTASASFPDECEHVQYVLSSLAVSFFELLLFFGRDEFYEEPLKDILGSFQECQNHLRRYGNVNLELVTRIIRDGGPWEDPVLQAVLKAQPASQEIVNKYLSSENPLFFELRARYLIACERIPEAMALIKSCINHPEISKDLYFHQALFTCLFMSPVEDQLFREHLLKTDCKSGIDIICNAEKEGKTMLALQLCESFLIPQLQNGDMYCIWELIFIWSKLQLKSNPSKQVFVDQCYQLLRTATNVRVIFPFMKIIKDEVEEEGLQICVEICGCALQLDLHDDPKTKCLIYKTIAHFLPNDLEILRICALSIFFLERSLEAYRTVEELYKRPDEEYNEGTSSVQNRVRFELLPILKKGLFFDPEFWNFVMIKKNCVALLSDKSAVRFLNESTLEN------------------------------------------------------------------------NAGNLKRTEEQQGLDEGFDSLT---------------------------DQSTGETDPDDVSGVQPKGH----------------------------------INTKKNLTALSTSKVDHNVPRHRCMLCNKEFLG-----------GHIVRHAQAHQKKGSFACVICG----RKFRNRGLMQKHLKNHVKKIQRQQIAAAQQDDQE-----VTALEEINCSSSSISFENGNSDSKDLEVETLTASSEGNKEVIPEHVAEFIEIPIS-------------------VPEDVIENVIENGSPNNSLNNVFKPLTECGDDYEEEEDEEGDYEEDDYDLNQETSVIHKINGTVCHPKDIYATDQEGNFKCPALGCVRIFKR----IGFLNKHAMTVHPTDLNVRQTVMKWSK-------------------------GKCKFCQRQFED----SQHFIDHLNRHSYPN---------------------------------------VYFCLHFNCNESFKLPFQLAQHTKSHRIFQAQCSFPECHELFEDLPLLYEHEAQHYLSKTPESSAQ--------------------------PSETILWDVQTDSNPNQEKDSSSNEKQTISLPVSTSKSRKESTEPKTCIESMEKKTDSLVQNGNERSDDTVSN-----------------------ISLIDQKMPDIEPNSENNCSSSDIVNGHSEIEQTPLVSSDPALKIDTNRIRTENGSILPSVVP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QEHNTLPVSQAPSKPNLTSEHTSYGLILT-KPYVRPLPPSYLDERYLSMPKRRKFLTDRVDACSDQDNVYKKSVKRLRCGKCLTTYCNAEALEAHLAQKKCQTLFGFDSDDESA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6I6-1", "uniprot_id": "A0ACD6B6I6_DANRE", "id": "A0ACD6B6I6-1", "name": "", "aln": "MAEEESELELDRFKKELETLLKISASDE--------------------RGLQSKTYCERFCELVVEHTGRWQVPLPQLQVLRSALCSFVQGVASFPPECEHVRYTLSSLALSIFELLLFFGKDEFIEHPLKDILDSFQVCYASLVSHQNVYLLQVRHIIKDGGPWASPVLEAILKDSELPQEDVDKYLSSEASIFFELRLRYLVACERLPEALALTRRCIQHSVVGKDLYYKQAYLICLWKAALHQCLN-KEMADIDGKDAVEILCMMENEEKDETVLMLSKSFLSQKLQTGDMYYLWDLVFIWSRLYMRLNISKQGFLEECKVMILSATNIKAIFPFMKVVLTEFGKDGREFCVELCARALQTDLQNDPATKTLFYKTVAYLLPNDLEVCRACALLIFFQERTVESYKNVFLLYIHPDQQYHVDTGLVGNSVRFEVLQILKKDLYFDPEFWSILNIETNCLKLMSDKVGKAALCEIMQKDKWLPSYCVKGCCQCHSNDTDRTVSKAENHTSHIDQETTSMKMWVKFPSEDASSKTPSKKRGRKPGTRLVKNSDACPVRRSFRQLDLEKDYERKLNSRHQRRSRQTEMNTLKRKGRKPQWLLDQLAGHSENSEPRQVKKPGRKPKESHILREILLEPPVSEITVVFSYPDNEVDIAPNVQATQVSAETPHMTEKSTDKTSSLENLKWPQSALSLLELLSAESPPRSKKDLRMKDEFVFREQGPSMVRKFHTYSRPVELEKISFNSLPREQEAKLNHNESKEESVATEQLCEPAESPEVVKHVKQSVEIKSTPIPAITAETAPAVEAIREPVKECTEDPKVGEFSSPQDTDMQFPLYGPYSPISPPESTNVDNEPELSTPTISDTISAEGTSLTTAATISLSDSTPENITSLPEEAPPVLTEVAVLPDDTVANTYASSEIVPESTDMSVVPPRTKEITEMNAAVDDLVANRIPQSDTSCQLSVNCSYCNKEIKFPHILRHALWHHRIEKKCMFCHKRYAHGRSPSVHFKVHIQQLKQSNGLLNKNIPKKAAETSSQRVQKRRVKRGRPPIRNKLRNIKMRLNCTLNIADMHKDGQNSDQVRLRARLVKNSDPGKATKEPKEKASKMKKRHLKRVLVKRPQSRDENKKLFRMRLEWKRTKTIQAPTPKDNHLESKSNSAPRVNGVIRKKRKDKSVSETNLSNEIAQTSVPHESRVKTENVECSESQKGTEIQRDKESQKDIVKCQSENAGVIKDKIKSKSKRTIEMLKTVLKKKIAPEEQKEDGDAVKRRKISSPEVSSENQQPKDSNTVQKEVNAVENKNGTQKKSKVPSTPFQGKRTGASTQVKCPVEICTFSAKSILVLSHVLSHHLSDKKALVFFYDFGKEKCLYCCRKICNPQHFFDHVMSHRGELKFPCYHYGCKQRFRTRMELSEHVLVHLPLRAMCCFPGCSMQLQSMMLLYKHEKLHYEENPNLETKSILCKESEPLVHARLEDGTVAAAKSSVNQLTTTILKDSSSGKQDDEEKPLVLNKSSVNYSSKNHSLVNGHDETDKVVPQKPSDPVIKVQEAPAAKKQTNKQFIRPLPSSYLDESYTSMPKRWKELQVGSKLPG-TVSIPEIPPTRQRCSRCFQSFDSEEELQKH--KDKCTSLFGFDSDDESAS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******: * :*: :** :::: . . *:.*: **.***::* :::*************::***.*. . **** *****:*.*****:*:********:*** *.******.*** * * : ** * * :**:***** .***:*:** . .** *:****** .:***** ***:****:***:** : **:*. :.****::** : **: :.:.: * :.: . * *..::*:* *:* * .* *.:*** :**.**** :*:*:*:**:* :: * *** *:::* :: :***::.******:: *. ::* ::***:*. *** **::** ** *:***:*::******: * *** :** **::::*:.* ** :**::* . . * * ****:* ****.*:******.:: *:.**: *: ** . * * :: : ::: * .::: ** :*.:: .: *: *: *.: . : .*.:: .. . : . * * :: * : : *..*. * ***:. . : * .:.: *:* * :::: : . * * * . :.. : . : *. : ::**.: *.* * : * : * * . *. :..*: * .: ..:. . . . . : . .. :. .. *.* *. .. * : :. * :* . : .. : :* : * ** **:::: . * ** *::: . .* : : :* : .* : * *:.: . . :* *. . : ::. :: * * *:* : .. .:: . * .: .: :: :. : * . :: *.:..: ::..:* ..* *. :::.:*:. * : :. . :.. . .:. ... ::: : * ..:**: * . ::.. *.* **.* :. :.:. . * * ::****.***** * ***** * * . . .: : . .* **.:*: :: . * *: * :.** :*********** ", "identical_positions": 354, "similar_positions": 363, "identity": "21.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1426", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVK6-1", "uniprot_id": "C2D1B_RAT", "id": "Q5FVK6-1", "name": "Coiled-coil and C2 domain-containing protein 1B", "aln": "-MPGPRPRKGPKTSGQGAETAKQLGLFVEFNPEDMLLGMDETEDDGDLEAELLALTGETGSTSRKPAPKGRAPLPMAHIEKLAADCMRDVEEEGEEEEGLEDDADLLTELQEVLGVDEETGLVDDSEETSPDLSEEKT-RDNTEQPVAPAAFQQALPAAVAQAGGPRGLQALLEERIQNYREAAASAKEAGEAAKARRCERGLKTLESQLATVRKGGKICEDEIPPPVALG-----KRPPAHQERPSKDSEID----------SAGSCAMD--------------PGDLSQPE---SSLPAVAALPDS--DPDPQALLLARQREYKAAALSAKRAGDLDRARELMRIGKRFGTVLEALEKGQPVDLSGMPPAPEDLKALPQASEASAATQVLSPAVEQMQPVMSSDLPATPAAPAEPKTVLDALQQRLNRYREAGIQARASGDERKARMHDRIAKQYQDAIRAHQAGRKVDFAELPVPPGFPPIPGLEPRKDTEEDSVTATLAAAQKLAS-EDTALVDEDEER-------DTPAQAPLAKKP---AQPLVP-SSHLLNEPKASSSKESLSPSVREQVTLLEARKLQYQRAALQAKRRQDLEQAKSHLRVAKSLEAQIIQARAGQPIDLSKVPSPLTDE---EGDFILIHHEDLRLSQKAEEVYAQLQKILLEQHEKCLLFSKQFMHQGNVAETTRFEKLAEDRKKQLEILQLAQAQGLDPPSHHFELKTLQTVRIFSELNSTEMHLIIVRGMNLPAPPGVTPDDLDAFVRFEFHYPNSDQAQKSKTAVVKNTNSPEFEQVFKLNINRNHRGFRRVIQSKGIKFEIFHKGSFFRSDKLVGTAHLKLERLEKECEIREIMEVLDGRKPTGGKLEVKVRLREPLSSQDVQMVTENWLVLE-PRGL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BRN9-1", "uniprot_id": "C2D1B_MOUSE", "id": "Q8BRN9-1", "name": "Coiled-coil and C2 domain-containing protein 1B", "aln": "-MPGPRPRKGPKTSGQGAETAKQLGLFVEFNPEDMLLGVDETEDDGDLEAELLALTGETASRSRKPAPKGQAPLPMAHIEKLAADCMRDVEED-EEEEGLEDDADLLTELQEVLGEDEEAGLLDGSEAASPDLCEEKT-WDNTELPVEQAACQQAVP-AAAQAGGPRGLQALLEERIRNYREAAASAKEAGEAAKARRCERGLKTLQSQLATVRKGGKICEDEIPPPVALG-----KRPPAPQERAIKNPEID----------SPGPCAME--------------PGNLSQPE---SSLPAIAPLPDS--DPDPQALLLARQREYKAAALDAKRAGDLDRARELMRIGKRFGTVLEALEKGQPVDLSGMPPAPADLKALPQASKASSATQGLSPAVEQMQPVMASDLPATPVAPAEPTTVLDALQQRLNKYREAGIQARANGDERKARMHDRIAKQYQDAVRAHQAGQKVDFAELPVPPGFPPIPGLEPRKGSEQDSVAATLATAQKLAS-EDAALVDDDEES-------DTPAQAPLAKKP---AQTLVS-PSHLLTEPKASSSKESLSPSVREQVTLLEARKLQYQRAALQAKRRQDLEQAKSHLRVAKSLEAQIIQARAGQPIDLSKVPSPLTDE---EGDFILIHHEDLRLSQKAEEVYAQLQKMLQEQQAKCLLFSKQYMHQGNVAETTRFERLAEDRKKQLEILQLAQAQGLDPPSHHFELKTFQTVRIFSELNSTEMHLIIVRGMNLPAPPGVTPDDLDAFVRFEFHYPNSDQAQKSKTAVVKNTNSPEFEQVFKLNINRNHRGFRRVIQSKGIKFEIFHKGSFFRSDKLVGTAHLKLERLEKECEIREIMEVLDGRKPTGGKLEVKVRLREPLSSQDVQTVTENWLVLE-PRGL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T0F9-1", "uniprot_id": "C2D1B_HUMAN", "id": "Q5T0F9-1", "name": "Coiled-coil and C2 domain-containing protein 1B", "aln": "MMPGPRPRKGPQARGQGVAAAKQMGLFMEFGPEDMLLGMDEAEDDEDLEAELLALTGEAQTTGKKPAPKGQAPLPMAHIEKLAADCMRDVEEE-EEEEGLEEDAELLTELQEVLGVDEETEPLDGDEVADPGGSEEENGLEDTEPPVQTAVLTASAP--AAQAGASQGLHALLEERIHNYREAAASAKEAGEAAKARRCERGLKTLESQLASVRRGRKINEDEIPPPVALG-----KRPLAPQEPANRSPETD----------PPAPPALE--------------SDNPSQPE---TSLPGISAQPVSDLDPDPRALLSSRQREYKVAALSAKRAGELDRARELMRIGKRFGAVLEALEKGQPVDLSAMPPAPEDLKPQ-QASQAPTAPSVIPPAVERVQPVMAPDVPATPVAPTESQTVLDALQQRLNKYREAGIQARSGGDERKARMHERIAKQYQDAIRAHRAGRKVNFAELPVPPGFPPIPGLESTMGVEEDAVAATLAAAEKLASAEDSAPADKDEDEPPGHLQGEPPAQAPVAKKP---ARPTVP-SSQRLPEPRASSSKESPSPSVREQLALLEARKLQYQRAALQAKRSQDLEQAKAYLRVAKWLEAQIIQARSGRPVDLSKVPSPLTDE---EGDFILIHHEDLRLSQKAEEVYAQLQKMLLEQQEKCLLFSKQFMHQGNVAETTRFEKLAQDRKKQLEILQLAQAQGLDPPTHHFELKTFQTVRIFSELNSTEMHLIIVRGMNLPAPPGVTPDDLDAFVRFEFHYPNSDQAQKSKTAVVKNTNSPEFDQLFKLNINRNHRGFKRVIQSKGIKFEIFHKGSFFRSDKLVGTAHLKLERLENECEIREIVEVLDGRKPTGGKLEVKVRLREPLSGQDVQMVTENWLVLE-PRGL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ILN1-1", "uniprot_id": "A0A0R4ILN1_DANRE", "id": "A0A0R4ILN1-1", "name": "Coiled-coil and C2 domain-containing protein 1B", "aln": "-MFARKNKRAAAPKGQGAAAAKQMGLLLDFKPDDMMD-MDQDLDDPSLEAEFAAIVGKKPNVPTRAKKAGKAPLPMEDIEKMAEACMKDFDDD--EDESVEDDEDLLAELQEVVGEEE----TDDSGATTPTFT------VSAETPADATPESQETK----VSSVPGSIEHTLEERISLYRMAVTNAKAAGETSKARRYERGLKTLQTMLATVRKGGKIDESEIPPPVACGGPVGSSRPPAPAVSPDEQEECDSAVEISPVSAEAAPVVMDTESNIRDESSGVTSPASLSSPEGEHASSEAEKHLVDFPVGQPTKDTLLEQQKEYRMAALKAKQAGDIDQAKMHIKASKGFDAAIEALEKGQPVNVSSLPPP------LAQVTQAPPQTAVK---------VSPSPSGETASGPAQPNTVLEALEQRMAKYKEAFTQAKASGDERKARMHDRIAKQYHAAIRAHKAGRPVNYDELPAPPGFPPIPGQKAT--SPEQGLAAVLETANKLTSNEARDGQDEDEEEE------EKALNLSGQKKPTLVVQPTVQEPKQRTPSPDRTSKRGSLPDAAQQQLEFLEGRKKQYMKAALQAKQKKDLEQAKTFLRTAKGLEPMIEAARSGKTVDVSKVPSPPGDE---DEDFILVHHSDVQLSEKAEEVYTQLNKLLNEQHEKCVTYSKQFTHLGNVAETTKFENMAEKCKKSLEILKLAQNRGLQPPKHHFEERTYRTVRIFPELSSTDMVVVIVKGMNLPAPSGVATNDLDAYVKFDFPYPSSEQPQKHKTAVVKNTNNPEYNQSFKLNINRNHRGFRRVIQSKGLKLEVLHKGGFLRSDKPVGSAQIKLEKLEAQSEVREIVELMDGRKATGGRLEVRVRLREPLGGQELQTVTERWVVLEEPQVLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKJ9-1", "uniprot_id": "C2D1_DROME", "id": "Q9VKJ9-1", "name": "Coiled-coil and C2 domain-containing protein 1-like", "aln": "-MFSRKKPEPAKRRQHDLSQFGLTEIPDDFDPSAGYG--EDDGGDSDLEAELAAITGGEGAKPKPKPK--AKLLPASDLDKMIADSLRDVSDD-DDDDNLESDPDLLGELSGIGGLEEAE----------------------EEEPVAQPPAASEEPVQTFLPTTTVDTLSIIKQRLEMYKQAEANAKTAGDSGKARRFGRGLKTLKDLHRQAAAGKSINVDDIPPEVSVKP----IGGQAPPVPAEESPAPS---------TPASPPPVP--------------SRAAPDPPTPGTPVEPTTSVAPTSPPNPLVTQMRSRQTDYKAAALQSKRSGDISTALQFLKVVKQFDVVIKMCEDGQEVDLSDMPPPPAEFLEFLKKMQEEAAAEAVAEPTAAPEPTPVAPAP----VLAAATNMLEALQQRLEKYQSVEAAAKAENNSGKARRFGRIVKQYEDAIKLYKAGKPVPYDELPVPPGFGPLPTADAAPVAPTPSLPTSPTSPPPTASTSAGGTPSSSSATTP-----TAPRKAPSPPKP--------------KELTTRTSGNQQKNNIAEQQMKLLLERQKEFKLAAIEAKKAGEIDQAKEYLKIFKGFDSLLNAASSGLPVDLSTLPVPPSQRDNLEASFAIVSAEECDPTDDICEIGVRMEEQLAKQLMMCKNTRDHHKAMGDVAGMNRFENLALTVQKDLDLVRYSKRKNEPLPKFHYEKRSFNIVHCNTDLTDSELEIVVVRGISYNVAN---PKDVDTYVRVEFPLLN-DESFKTKTNVIRDTSSPDYDERFKVDIQRTNRQFQRIFKRHGVKFEIYSRGGFLRSDTLIGTVNVKLQPLETKCEIHDTYDLMDGRKQVGGKLEVKIRVRNPILTKQMEHITEKWLVLDA-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : . . :. : :* *. :: .* .****: *:.* ** .::*: .::*..:: :::.:*.* :** **. : * :* * *. . . . . :::*: *: * :.** **::.**** ******: . * .* .:*** *: * . .. . ... : . ..* :. : :* :*: ***.:*::*::. * :: * *...:: *.** *::* :**. : : . . . . : . .:*:**:**: :*:.. *:: .:. *** . **.***. *:: ::**: * : ***.**** *:* .. .:.: :. :* . .... . : . ** . :* . . ..:*: :* *: :: **::**: :::*** .*: * ::. : * :* .:*:*.:* * :. : .* :: .: ::. *: .:::: * :* * .:. *:** .:**.:* :*.*:::: :: :. *..*:* :: . *: .:*..::: :::*:*:. .. ..*:*::*:.:* . ::. * ** *:::*..*:::: **::*:*.:* *:*::: :*:*:*: :*.*:***. :*:.::**: ** :.*::: :::**** .**:***::*:*:*: :::: :**.*:**: ", "identical_positions": 184, "similar_positions": 299, "identity": "20.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1428", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TCU6-1", "uniprot_id": "PREX1_HUMAN", "id": "Q8TCU6-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein", "aln": "---MEAPSGSEPGGDGAGDCAHPDPRAPGAAAPSSGPGPCAAARESERQLRLRLCVLNEILGTERDYVGTLRFLQSAFLHRIRQNVADSVEKGLTEENVKVLFSNIEDILEVHKDFLAALEYCLHPEPQSQHELGNVFLKFKDKFCVYEEYCSNHEKALRLLVELNKIPTVRAFLLSCMLLGGRKTTDIPLEGYLLSPIQRICKYPLLLKELAKRTPGKHPDHPAVQSALQAMKTVCSNINETKRQMEKLEALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFDNLLVYCKRKSRVTGSKKSTKRTKSINGSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDAIIREREQRESLKLGMERDAYVMIAEKGEKLYHMMMNKKVNLIKDRRRKLSTVPKCFLGNEFVAWLLEIGEISKTEEGVNLGQALLENGIIHHVSDKHQFKNEQVMYRFRYDDGTYKARSELEDIMSKGVRLYCRLHSLYTPVIKDRDYHLKTYKSVLPGSKLVDWLLAQGDCQTREEAVALGVGLCNNGFMHHVLEKSEFRDESQYFRFHADEEMEGTSSKNKQLRNDFKLVENILAKRLLILPQEEDYGFDIEEKNKAVVVKSVQRGSLAEVAGLQVGRKIYSINEDLVFLRPFSEVESILNQSFCSRRPLRLLVATKAKEIIKIPDQPDTLCFQIRGAAPPYVYAVGRGSEAMAAGLCAGQCILKVNGSNVMNDGAPEVLEHFQAFRSRREE-ALGLYQWIYHTHEDAQEARASQEASTEDPSGEQAQEEDQADSAFPLLSLGPRLSLCEDSPMVTLTVDNVHLEHGVVYEYVSTAGVRCHVLEKIVEPRGCFGLTAKILEAFAANDSVFVENCRRLMALSSAIVTMPHFEFRNICDTKLESIGQRIACYQEFAAQLKSRVSPPFKQAPLEPHPLCGLDFCPTNCHINLMEVSYPKTTPSVGRSFSIRFGRKPSLIGLDPEQGHLNPMSYTQHCITTMAAPSWKCLPAAEGDPQGQGLHDGSFGPASGTLGQEDRGLSFLLKQEDREIQDAYLQLFTKLDVALKEMKQYVTQINRLLSTITEPTSGGSCDASLAEEASSLPLVSEESEMDRSDHGGIKKVCFKVAEEDQEDSGHDTMSYRDSYSECNSNRDSVLSYTSVRSNSSYLGSDEMGSGDELPCDMRIPSDKQDKLHGCLEHLFNQVDSINALLKGPVMSRAFEETKHFPMNHSLQEFKQKEECTIRGRSLIQISIQEDPWNLPNSIKTLVDNIQRYVEDGKNQLLLALLKCTDTELQLRRDAIFCQALVAAVCTFSKQLLAALGYRYNNNGEYEESSRDASRKWLEQVAATGVLLHCQSLLSPATVKEERTMLEDIWVTLSELDNVTFSFKQLD-ENYVANTNVFYHIEGSRQALKVIFYLDSYHFSKLPSRLEGGASLRLHTALFTKVLENVEGLPSPGSQAAEDLQQDINAQSLEKVQQYYRKLRAFYLERSNLPTDASTTAVKIDQLIRPINALDELCRLMKSFVHPKPGAAG-SVGAGLIPISSELCYRLGACQMVMCGTGMQRSTLSVSLEQAAILARSHGLLPKCIMQATDIMRKQGPRVEILAKNLRVKDQMPQGAPRLYRLCQPPVDGDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G9V8-1", "uniprot_id": "A0AC58G9V8_DANRE", "id": "A0AC58G9V8-1", "name": "", "aln": "MSHSYEMLGAERLLWGCGQALMADCHAEDASP--QGHTRLFINLGSPQQNEPPTYPAYVFCNGCPSSCN----PSLAFLQRIRQTAEN--QQCLTQEQVKVLFSNIESILDVHREFLSTLDASLQPEPQAHHSLGHVFLQFKVRFSVYGEYCSNHEKALRLLMELNKIPHIRAFLLHLMLLGGKKSTDVPLEGYLLSPIQRICKYPLLLRELLKRTPKKHSDYPAVEEALQAMKAVCCNINETKRQMEKLEALEILQSHIEGWEGTNLTDICTELLLQGNLLKISAGNIQERVFFLFDNLLVYCKRKSRVSG-KKSTKRTKSINGPQYVFRGRINTEVMEVENVEDGTADYHSNNYTVTNGWKIHNTAKNKWFVCMAKNAEDKQKWLDAILKEREQRESLKLGMERDAYVMIAEKGEKLYHMMMTKNRHLIKDRRRKLTNVPKCFLGNEFVSWLLESGEISKAEEGINLGQALLENGIIHHVSDKHQFKNEQVLYRFRYDDGTYKARSEMEDIISKGVRLYCRLHSLFTPVVKDRDHHLKTFKSVIPASKLVEWLVSQGDSASREDAVTLGVGLCNAGFMHHVLEKSEFKDESQFFRFYADEETEGTSSKSKQLRSDFKLIENILAKSLVIHPEEEDYGFEIEEKNKAIIVKSVSRGSYAEMAGLQPGRKIYSINEDLVFLRPFSEVETMINQSFCIRRSLRLLVATKNKEIVKIPDVHGTLPFVLSGSCPPHIHAVKKGSEAAAAGLQPGQCVLKVNGNNMNQSGYQEVLEHFSGYQPVLEQQDTSCGQWAYRVYEDVEEQMSFRGCENGSDS------EDGCTNGTGSVRRLEQLSISDDGPLVSLNVDNVHVEHGVVYEYVSPAGIKHCVLEKMVEPKGCFNLTAKILKAFVKDDSLFVKSCRQLMALNDKVVTMPQFEFRNICDTKLESIDKRISSYKQFVEELQTKAWPTFKQASTKPHILGCMDFVPTNCHLNLMQVSCPKNTSSAGRAFSIRFGRKNSFFGLDPDQANLNPMSHSVHCVTSMGAPSFSCQSLDEETENGEGNSEDSR-------KHEEGGLSFLLKQEDTESQDNYICLYNRLDIAVREMKQYVAQIDVLLSSITGPTQPQGSEPPSFESGPSTSPIPEETDQDKTEHCGNKRVCFKVNEDDQEDSGHDTMSYRDSYSECNSNRDSVLSYTSVRSNSSYLGSDEMGSGDELPCDMQIPFDKQDKLHGCLEHLFNQVDSINSLLKGPVMSKACEETKHFHTDHSQPEFRHTDDWTVRWRYVLHKNIQEDPWNLPISIKSLINSLHRFVEDGRSQLLLALLKCTDTKLQLRRDVIFCQSLVGALCALAEQLVTALNLRFNNNGEYEEDSKEVSHKWLEQISTIGVLFNFQSTLSP-HVREERIMLEDTKAALQDLEKVTVLFRPLENECLVPNTSVHYQVEGSRQAIRVTMFLDNCHFSELPTRLQNGGSLKLQSVLFTRGLEKPEGVLSQDFVTMEEFQQRTNALSLEKVKGYYRKLRAFYLEKSNS--DSNSTAMKIDQLLRPLNTLDDLCRLMQTYMNVKASSAGQPSGVSVLLVSSELCNRLGACQITMCATGMQRCTLTVSLEQATILARNHSLMPRCLMQTMDLMRKQGTRVEISAKNLRVMDQMPPLAPRLFRLCLPPSDGDL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:* *.*:. .* :* .*:. .* * :* . : . . . . ***:****.. : :: **:*:*********.**:**::**::*: .*:****::*.**:***:** :*.** *************:****** :***** *****:*:**:********************:** **** **.*:***:.******:**.**************** **********:*******:*****.************.*****************:* ************. *:*************************.***********************.**:********::********************************.*: :*********:.***********:**** *****:***:**************************:***************:***:*************:***:****:****:***:*.****:**::***. :**:**:******* ************:****:***:**** ******.****.****:****** *:* *:******:*******::****.*** **:**** *********************:::***** **.******** ***:**** .** * : *:.**:::** :**** **** .***:*****.*: :.* ******..::. *: . ** *:.:**.:* : : ... . * ** . .. : :**:.:*.*:*:*.*****:**********.**:: ****:***:***.******:**. :**:**:.**:****.. :****:**************.:**:.*::*. :*:::. *.****. :** * :** *****:***:** **.*.*.**:******** *::****:*.:*****:: **:*:*.***:.* . * :*:* :.* :*: ********** * ** *: *:.:**:*::******:**: ***:** **. ..:.. *...* . :.**:: *:::* * *:***** *:******************************************************:** *********************:********:* ****** :** **::.:: *:* * ::: .********* ***:*::.::*:****:.************:******.****:**.*:*::::**::**. *:********.*::.*:*****::: ***:: ** *** *:*** **** .:*.:*::**. *: *: * *.**.*.*::******::* ::**. ***:**:**:.*.**:*::.***: **: **: * . : *::** ** *****: ***********:** *:.:**:*****:**:*:**:*****::::: *..:** . *..:: :***** ******:.**.*****.**:******:****.*.*:*:*:**: *:*****.**** ****** **** ****:*** ** ****", "identical_positions": 1089, "similar_positions": 360, "identity": "65.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1435", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P1R4-1", "uniprot_id": "DUS1L_HUMAN", "id": "Q6P1R4-1", "name": "tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like", "aln": "-----------------MPKLQGFEFWSRTLRGARHVVAPMVDQSELAWRLLSRRHGAQLCYTPMLHAQVFVRDANYRKENLYCEVCPEDRPLIVQFCANDPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFLQDEWDLLQRMILLAHEKLSVPVTCKIRVFPEIDKTVRYAQMLEKAGCQLLTVHGRTKEQKGPLSGAASWEHIKAVRKAVAIPVFANGNIQCLQDVERCLRDTGVQGVMSAEGNLHNPALFEGRSPAVWELAEEYLDIVREH-PCPLSYVRAHLFKLWHHTLQVHQELREELAKVKTLEGIAAVSQELKLRCQEEISRQEGAKPTGDLPF-HWICQPYIRPGPRE-------GSKEKAGARSKRALEEEEGGTEVLSKNKQKKQLRNPHKTFDPSLKPKYAKCDQCGNPKGNRCVFSLCRGCCKKRASKETADCPGHGLLFKTKLEKSLAWKEAQPELQEPQPAAPGTPGGFSEVMGSALA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S7L0-1", "uniprot_id": "B0S7L0_DANRE", "id": "B0S7L0-1", "name": "tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like", "aln": "MCRIYRSLAVPQATAGSMTKPLGFEFWRRTLKGARFVVAPMVDQSELAWRLLSRRHGAELCYTPMLHAQVFVRDANYRRENLYSEVNQEDRPLITQFCANDPEVFIQAALLAQDYCDAIDLNLGCPQMIAKRGHYGVFLQDEWDLLEKMIKLANEKLSVPITCKIRVFPEIEKTVKYAKMLEKAGCQLLTVHGRTKDQKGALTGIASWKHIKAVREAVNIPVFANGNIQHLSDVHHCMEETGVQGVMSAEGNLHNPALFEGRSPPVWEMAEEYLDIVEKHSPCSLSFVRAHIFKLWHHTLQIHQDLREDLAKAKNVDGIVEVNRQLKQRCQEEMAKDESEWNQTGLPFPHWICQPYVRPPPKDPNTENGQKSQETKAVSVKRALEDSDGPNDAMSKNKQKKKARNPHKNFCPELKPKYIKCEQCGNPKGNKCVFNLCRGCCKRKAFKEVADCPGHGLKFKTKALRQCNSDTSGGGLTNGKASTQTVSTAVHDPLQA---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.* ***** ***:***.**********************:*******************:****.** ******.**********:******************************.*********::** **:******:**********:***:**:*****************:***.*:* ***:******:** ********** *.**.:*:.:************************.***:********.:* **.**:****:*********:**:***:***.*.::**. *.::** *****::::*. .*** *******:** *:: *:*. .. *****:.:* .:.:*******: *****.* *.***** **:********:***.*******::* **.******** **** :. . : * : :.:: .. .. : : : ", "identical_positions": 336, "similar_positions": 90, "identity": "67.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1437", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQQ1-1", "uniprot_id": "D3ZQQ1_RAT", "id": "D3ZQQ1-1", "name": "", "aln": "MEPDVIRMYSSSPPPLDNGAEDD-----------DEDEFGEFGGFS--------------------EVSPSGVGFVDFDTPDYTRSKEDFVPSNHFMPIDEYSENVDSLTSLKSIQNGKDKDITAELPTPSKGQSDVVLSATSKAMVPSKALDTPLCGRESLGGVDKGVMQGPS-------------TGQLPSFSPADFRTDTNIVHQTTQLESCNGEKPACLEVLTN------GFAGVETANPQGTEDLDSVADSKGSRPLSTS---------------------------CGTECILESAASPATEFADFSTFSQTE--------------------RTQLEELECAVVNDGDALTIQGNSKSHRVKELNCMKEVTLGGSFADTGDTERE----------HQVCVSDFHAIADRGLSVEKQDLQTLQQDEFLNSRIQSEAWSLV-----------DSNENSEAIRRERCKTEEN-DFFVAK--------------------CADLSMDSIKTSDVNEIGSSKEENRKL-TNPKSPNPDPTEESVLDDSAASMKNGDSFNGFVTCHDTNED------DFGDFGTASGTTPPFVTSTQDSMS--------DVTFEDSSEHFLHFSEPGDDFGEFEDTNAISCPEEMIFTESDLRQTSDGLSEECPLEGESGGKDSEPDSKLKNGQ--------DGEFGDFDSVPNTQG--SAFQDSDDFADFSSAGPSQAVDWNAFE-DEQKDSCSWAAFGDQQATESHHRKEVWQSHRTDGTLDTLGTPRTHSVSSAASKGAVASGHLQEPATSAQTALLNRLERIFEACFPSVFVPDAEEEVTSLKHLLETNYSPVKAREA--------------LAECGELRDVWAELQDIHDAHG------------------------------LRYQWGGSHSNKKLLCSLGIDTRNILFTGNKKQPVIVPMYAAGLGMLEPTKEPLKPLSAAEKIASIGQTTIMTPEMNTCTSDP-------FQESLPPVQFDWSSSGLTNPLDG----------------------------VDPELYELTTAKLETSTSSLRVTDAFAKLMSTVEKTSTST-------------RKPK-REEHLSEEAVKVIVSLPDLTFMHAKVLMFPATLTPSTSSQGQADA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80WT5-1", "uniprot_id": "AFTIN_MOUSE", "id": "Q80WT5-1", "name": "Aftiphilin", "aln": "MEPDIIRMYSSSPPPLDNGAEDD-----------EEDEFGEFGGFS--------------------EVSPSGVGFVDFDTPDYTRPKEDFVPSNHFMPIHEYSEDVDSLTSFKSVQNGNDKDITAELSTPVKSQSDVVLSTTSKEMIPSKTLDPSIDGMESLEDLDKVVVQGPS-------------TGQLRSFSPGDFRTDKNIVHQTKQLESCNGEKPPCLEILTN------GFAGLETVNPQGTDDLDNVADSKGSKPLNT----------------------------CGTECILESAASHATEFADFSTFSQTE--------------------RTQLEEIECPVLNDGDTLTIQGNSKGPRVKELNCVKEVTLDGSFEDTGNTERE----------HQVCVSEIHAVADRGLSVEKQDLQTLQQDEFLNSRIQSEAWSLV-----------DSSENSEAITKERCKMEKN-DLFASK--------------------CADLSMDSVKTSDVNEIGSSKEENRKL-TNPKSPDPDPTGQNALDDSAASMKNGDSGNGFVTCHDTNED------DFGDFGTANGTTPPFVTSTQDSMS--------DVTFEDSSEHFLHLSEPGDDFGEFEDTNAVSCQEEMRFTESDLRQTSDGLSEECPLAGESGGKDSKPDSKLKNGQ--------DSEFGDFDSVPNTQG--SAFQDSDDFADFSSAGPSQAVDWNAFE-DEQKDGCSWAAFGDQQETESHHLKEVWQSQRTDETMGTLGTPKMHSVSSAASKGAVASGHLQEPGTSVQTALLNRLERIFEACFPSVFVPDVEEEVSSLKHLLETHSSPAKTREA--------------LADRGELRGVWTELQDIHDAHG------------------------------LRYQWGGSHSNKKLLCSLGIDTRNILFTGNKKQPVIVPMYAAGLGMLEPTKEPLKPLSAAEKIASIGQTTVMTPEINTCTSDP-------FQESLPPVQFDWSSSGLTNPLDASGGSTLLNLDFFGPVDDSSSSS-STIPGVDPELYELTTAKLETSTSSLRVTDAFAKLMSTVEKTSTST-------------RKPK-REEHLSEEAMKVIASLPDLTFMHAKVLMFPATLTPSMSSQEQADA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ULP2-1", "uniprot_id": "AFTIN_HUMAN", "id": "Q6ULP2-1", "name": "Aftiphilin", "aln": "MEPDIIRMYSSSPPPLDNGAEDD-----------DDDEFGEFGGFS--------------------EVSPSGVGFVDFDTPDYTRPKEEFVPSNHFMPIHEFSENVDSLTSFKSIKNGNDKDITAELSAPVKGQSDVLLSTTSKEIISSEMLATSIDGMERPGNLNKVVEQRQN-------------VGTLESFSPGDFRTNMNVVHQNKQLESCNGEKPPCLEILTN------GFAVLETVNPQGTDDLDNVADSKGRKPLST----------------------------HSTEYNLDSVPSPAEEFADFATFSKKE--------------------RIQLEEIECAVLNDREALTIRENNKINRVNELNSVKEVALGRSLDNKGDTDGE----------DQVCVSEISIVTNRGFSVEKQGLPTLQQDEFLQSGVQSKAWSLV-----------DSADNSEAIRREQCKTEEKLDLLTSK--------------------CAHLCMDSVKTSDD-EVGSPKEESRKF-TNFQSPNIDPTEENDLDDSLS-VKNGDSSNDFVTCNDINEDDFG---DFGDFGSASGSTPPFVTGTQDSMS--------DATFEESSEHFPHFSEPGDDFGEFGDINAVSCQEETILTKSDLKQTSDNLSEECQLARKSSGTGTEPVAKLKNGQ--------EGEIGHFDSVPNIQDDCNGFQDSDDFADFSSAGPSQVVDWNAFE-DEQKDSCSWAAFGDQQATESHHRKEAWQSHRTDENIDTPGTPKTHSVPSATSKGAVASGHLQESATSVQTALLNRLERIFEACFPSILVPDAEEEVTSLKHLLETSTLPIKTREA--------------LPESGELLDVWTELQDIHDAHG------------------------------LRYQWGGSHSNKKLLSSLGIDTRNILFTGNKKQPVIVPMYAAGLGMLEPTKEPLKPLSAAEKIASIGQTATMSPDMNTCTSDQ-------FQESLPPVQFDWSSSGLTNPLDASGGSTLLNLDFFGPVDDSSSSSSTTIPGVDPELYELTTSKLEISTSSLKVTDAFARLMSTVEKTSTST-------------RKPK-REEHLSEEAIKVIAGLPDLTFMHAKVLMFPATLTPSTSSQEKADG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NRF7-1", "uniprot_id": "A0A8M1NRF7_DANRE", "id": "A0A8M1NRF7-1", "name": "", "aln": "MEPDVIRIYSSSPPPMEDAGED------------EEDEFSDFTG------------------------VPNSTSFSEFDTPTTFNQ----------------SQALNATSPPELLSNGRIVGLSSQSAGSTKANG-VAPGGGQTGMPNGRTVS--------VEELKKLTEHQAH-------------ITSLEFPTSS--RTDN----------DCNG----TVEVLTN------GFASLEQAS---TPHKNNESD---------------------------------------------------DDFADFSAFSNAD--------------------HDQPSNTDWELSNQG--CRVAQN-------DVSDSVELSNQGSRLAQNDVSGE----------CEDSIEAVSKITGFELPSE-----------------SSEGLSNG-----------DLG-FHEGSDLDQRDLETNTTEYVS----------------------TSLTLNGVARSESDDNSVSPNGERCS-GGQSDEKGSETEETETETSFGRPLSTEALEEFG--------------DFSTTGSVP--SPPLQEETATPAD--------HSQLVEDD------DEDFGDFGDFGDANAFSAGGFADFDQ-----------------QGAETQVTQPEAAAEKTE--------DDEFGDFDTSKEFSKTDLPAEEATTSADFP--GSDSFADFSSAQGNDGADDGGWQAFSEPD--QSQNGEESWATFEQAQDGACAQMSGDKWQPDTAPPTGVE-----ERKSCTTAALVSRLEKIFQVSFELVVSPQVEDEVNTLHSFLKP-PSEEQDRDR--------------GQTSGAVRDVWQQLQDVNNAFG------------------------------LRYQWGGSHTNKALLCSLGIDTRNILFTGHKKQPVIVPMYAASLGMLEPTKEPVKPVSAAEMIASIAQSPSVATELSSCPPDS-------TQESLPPVQFDWSSSGLTNPLDASGGSSLLNLDFFGPVDESPSGTATSIPGVDPELYELTQVKLEVSGGSSRVVDAFARLMSTVEKTSTSTS------------RKPVPKEENLSPEAQRVISGLPDLSFMQAKVLMFPSTLTPLLPSSSTPD--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A4D6K2J4-1", "uniprot_id": "A0A4D6K2J4_DROME", "id": "A0A4D6K2J4-1", "name": "", "aln": "-MVNVPPLLCSTPPPIDFGEEDDDSGLQSTIHLDEGDEYSDFGLVSSSKEPPPPPDPVEEFREKPPDLLEDKQTVEAFNYQVKQKMDYDVFEETAPPTPPPLSLELDDEELEEHVPSLKLDSLSLYSTESVSAASTLSPVAETSAVAPPAMQTTKAHILSHQVTLEDVSDDSDEECSPKKPKELFIREGAVDFFAIEVLATPTLPYGEGFSEENVDTGKGEYVENTSQPEESFRSLEAQEESSNTLEKPMENQSRGLSNPPNQEESPHQWGEPANSDTYSFTNLDATPKDLVHKEIVPEMQEQEDDDDFGDFADFSAAEPQLEITENSTSAFETPSLAINSRTESQPLEVKTAPSTEESSKLPPAETDDGFDDFQEFATPANGNHGQSEDDDDFGDFAAPVVTPVSVPPPPPPAAVHLSIDERVKPVLDMMFPQPTELDSKSMDNRRPLAQCQRFNFGAIEHAQALDYQWSSSEMRHALVRSLGIDSRNILFGDKWNSSMPRFAANLSFDPLKPLKPQSTGAASSLEPISNSTSYQESHVQTLQLEQLDQLTVVANADKINLVTSNSHTNNNNDNGDNDVAAPVDQLDCMPPVMDLMTHNDHNLTIDLHHSPSLTHFATICNNNNNDNNNPNNLNNNHAKNTATMTITINTNLTAHDALLDFRLENAAATTASQTETRTGPSHGEGSTGSCSASNSDGEERPSHSHQPTAVPSPESNHIESTAAASAAAVAAAAATLPTTLSADSPAHKLNGGEQLHQQRSEPEQFDLRTTPPAAAPAQEEIVGSSMASYSVPLKETHIYTPSKSDTAVAKTTTLAPIDFDYEMAATGIIIDETVVKKEYRDVEYKPPFGLDSPSKLSGNGAASSFQLPPQTTEDDDFSDFQSMPAPRSRIDTPTFGEQMILSPAILLPQAIPLAKKPAATIEWG--DNALSSINAEEMARIEELFSSQAKPLTISASVAKKPAPSTPAQSQPQEDDEWSDFVSVPVTQQQPHHQQNAIANNNNIVNSNARKPAAPKEDDWSDFVSSTPPARPAPQFNSGAWQSANFYNNPLSLYQAQQQLQQQPHSNLVPKGSTSSSNNNNVPAIPQQIHIMHDFSTAPVSGGLGVGATYQQQHQRQQFQIGNAKVAPRISLIPDLSFVAPALPTNAGAFMGALPKPTFGGKK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : .*:***:: . ** : **:.:* . . *: . * :: : : . . .:: . . .. . : . : :.. . : : * . : :* :: .: * . :. : :*.**: ** : . : .. : . .. *.: . . . : .: : :. : .*:. . . :. : . * . : : * :: : . . . . . . . . * : . . : : . *.. **. : . .: .: .:: : :* . : : ::. : .: : ... *. . . . :: . . .. . : . :. : ..:. : . . :: : .. :. . :: : :*. : . : . : ::*.: . . :** .. : : : : **:.: * .* . * . *::. : . . :.*: : . . ... .: ::. .* : ***. :.* :: : :. * . * .. . . *:.: : :.. **:. :: : : . :. * :***:*: . : ..:: .. . ", "identical_positions": 55, "similar_positions": 253, "identity": "4.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1441", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NXS2-1", "uniprot_id": "QPCTL_HUMAN", "id": "Q9NXS2-1", "name": "Glutaminyl-peptide cyclotransferase-like protein", "aln": "MRSGGRGRPRLRLGERGLMEPLLPPKRRLLPRVRLLP-LLLALAVGSAFYTIWSGWHRR---TEELPLGRELRVPLIGSLPEARLRRVVGQLDPQRLWSTYLRPLLVVRTPGSPGNLQVRKFLEATLRSLTAGWHVELDPFTASTPLGPVDFGNVVATLDPRAARHLTLACHYDSKLFPPGSTP----FVGATDSAVPCALLLELAQALDLELSRAKKQAAPVTLQLLFLDGEEALKEWGPKDSLYGSRHLAQLMESIPHSPGPTR---IQAIELFMLLDLLGAPNPTFYSHFPRTVRWFHRLRSIEKRLHRLNLLQSHPQEVMYFQPGEPFGSVEDDHIPFLRRGVPVLHLISTPFPAVWHTPADTEVNLHPPTVHNLCRILAVFLAEYLGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BH73-1", "uniprot_id": "QPCTL_MOUSE", "id": "Q8BH73-1", "name": "Glutaminyl-peptide cyclotransferase-like protein", "aln": "MSPGSRGRPRQRLEDRGLMKPPSLSKRRLLPRVQFLPLLLLALAMGLAFYIVWNSWHPG---VEEMSRSRDLRVPLIGSLSEAKLRLVVGQLDPQRLWGTFLRPLLIVRPPGSSGNLQVRKFLEATLQSLSAGWHVELDPFTASTPLGPLDFGNVVATLDPGAARHLTLACHYDSKFFPPGLPP----FVGATDSAVPCALLLELVQALDAMLSRIKQQAAPVTLQLLFLDGEEALKEWGPKDSLYGSRHLAQIMESIPHSPGPTR---IQAIELFVLLDLLGASSPIFFSHFPRTARWFQRLRSIEKRLHRLNLLQSHPQEVMYFQPGEPPGPVEDDHIPFLRRGVPVLHLIATPFPAVWHTPADTEANLHPPTVHNLSRILAVFLAEYLGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q1LWV0-1", "uniprot_id": "Q1LWV0_DANRE", "id": "Q1LWV0-1", "name": "Glutaminyl-peptide cyclotransferase", "aln": "MSRAGR-RFKALHANNGQALAGCDPRRGRRVRVLLLLCLCGALSLAMILALYLSAEPSGSLLPHPADLIKDRLSHKPNKYSVAQAKKLAGQVDGHRLWETHLRPLLIERVPGTTGSQIIRQHILSQLRSLSAGWTLEENDFVSSTPKGDVTFTNLLAVLDPSAPRRLLLACHHDSKIIPADPKNSKRVFVGASDSAVPCAIILELASALDKQLKALKQQRSAVTLQLVFFDGEEAFEEWTDTDSLYGSRHLAELMSRTPHPAGSTKSSLLQAVDLLVLLDLLGAPEPLIVNHFDNTARWFDRLIAAEKRLHKQGLLTSHPSEQSYFRKDFYLGPVQDDHIPFLNRGVPVLHLIPTPFPVFWHTLDDVEERMHRPTVENLTRILAIFVAEYLSL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ..* * : :.* . .:* ** :* * **::. : .. . :: .. . *: : :.**:* :*** *.*****: * **:.*. :*:.: : *:**:*** :* : *.:*** * : * *::*.*** *.*:* ****:***::*.. ****:*******::***..*** *. *:* :.*****:*:*****::** .**********::*. **..*.*: :**::*::*******..* : .** .*.***.** : *****: .** ***.* **: . *.*:*******.*********.****..*** *.* .:* ***.** ****:*:****.*", "identical_positions": 181, "similar_positions": 106, "identity": "46.06%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1458", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V646-1", "uniprot_id": "G3V646_RAT", "id": "G3V646-1", "name": "", "aln": "MAAIVGERSGTEEACRHMESKEEFVKVRKKDLERLTTEVMQIRDFLPRILNGELLESFQKLKIVEKRLSKPPPPKPIKPIGLWGYTPIIPALRRPTQLDSGKYDLERKEQELEQLRLDCEHFKARLETALADSGREKKEKLALRQQLNEAKQQLLQQAEYCTQMGAVTCTLLWGVSSSEEVVKAILGGDKALKFFNITGQTMESFVKSLDGDVKEVDSD---ENQFVFALAGIVTNVAAVACGREFLVNSSQVLLDTMLQLLGDLKPGQCTKLKVLMLMSLYNVSINSKGLKYISESPGFIPLLWWLLSDPDAEVCLHAVRLIQSVVLEPDVFSKVASELQSSLPLQRILAMSKSRNSHLQSAARELLEDLRALDCSV--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D4G2-1", "uniprot_id": "HSF2B_MOUSE", "id": "Q9D4G2-1", "name": "Heat shock factor 2-binding protein", "aln": "MAATVGDGSGTEEACRNMESKEEFVKVRKKDLERLTTEVMQIRDFLPRILNGELLESFQKLKMVEK-------------------------------------NLERKEQELEQLIMDREHFKARLETAQADSGREKKEKLALRQQLNEAKQQLLQQAEYCTQMGAVTCTLLWGVSSSEEVVKTILGGDKALKFFNITGQTMESFVKSLDGDVKEVDSD---ENQFVFALAGIVTNVAAIACGREFLVNSSRVLLDTMLQLLGDLKPGQCTKLKVLMLMSLYNVSINSKGLKYITESPGFIPLLWWLLSDPDAEVCLHTLRLIQSVVLEPDVFSKVASELQSSLPLQRILAMSKSRNSHLQSAAQELLEDLRALDCNV--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75031-1", "uniprot_id": "HSF2B_HUMAN", "id": "O75031-1", "name": "Heat shock factor 2-binding protein", "aln": "----MGEAGAAEEACRHMGTKEEFVKVRKKDLERLTTEVMQIRDFLPRILNGEVLESFQKLKIVEK-------------------------------------NLERKEQELEQLKMDCEHFKARLETVQADNIREKKEKLALRQQLNEAKQQLLQQAEYCTEMGAAACTLLWGVSSSEEVVKAILGGDKALKFFSITGQTMESFVKSLDGDVQELDSD---ESQFVFALAGIVTNVAAIACGREFLVNSSRVLLDTILQLLGDLKPGQCTKLKVLMLMSLYNVSINLKGLKYISESPGFIPLLWWLLSDPDAEVCLHVLRLVQSVVLEPEVFSKSASEFRSSLPLQRILAMSKSRNPRLQTAAQELLEDLRTLEHNV--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JBW7-1", "uniprot_id": "A0AC58JBW7_DANRE", "id": "A0AC58JBW7-1", "name": "", "aln": "MKAVDPVNVPSSSAVQVVGS-DGFVQVRKRDLERLEAEVRTLRELMPKVINSDLIDTIHEERSLDA--------------------------------------FQELCDREQQERENCLHIQTRLDAALNECQNEKQEKLVLKQQLWECRGQLQQQKDFCTELGASCCTLLWSASQKEEAIRDILANGKLEDFLSIAGQTLETFIKLLVDEAKPQQSDNSHEHNFVLALAGVVTNIAAVSCGRDFLSSSAHILLGTMLQLLGLMKPGVFPKLKVLMLMALYNTTINVNGLKFISERPELLPLMCHLLEDPDPEVCLQSLRLLQSLILEREIMPGMATDFRRSFPLSRINHLVSSCHPTLKQTAQETLEDLAAVSKLCSGGTMTSKVELQPQLDNNSNTRNILY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..* : : : : **:***:***** :** :*:::*:::*.:::::::: : :: ::. :. :* : *:::**::. : .**:***.*:*** *.: ** ** ::**::** *****..*..**.:: **...* .*:.*:***:*:*:* * .:.: :** * :**:****:***:**::***:** .*:::**.*:***** :*** .********:***.:** :***:*:* * ::**: **.***.****: :**:**::** :::. *:::: *:**.** : .* :. *: :*:* **** ::. ", "identical_positions": 139, "similar_positions": 126, "identity": "34.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-146", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A183-1", "uniprot_id": "A0A8I6A183_RAT", "id": "A0A8I6A183-1", "name": "Cell division cycle and apoptosis regulator protein 1", "aln": "MAQFGGQKNPPWATQFTATAVSQP------------AALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPANYQLT-QTAALQQQ-----AAAVLQQ--------QYSQ-----------------PQQALYSVQQ-----------QPAVALPTSLSLSTPQPAAQITVSYPTPRSS-QQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLGAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQ------------------------------------------NQSQTQPLLKTPTAVIQPIVPQTTFGVQAQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQK-----AGLLQPPVRIVSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDR---------------SRERDRERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNVAVLDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQDLRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPNPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKKADGEQDEEEKDDGEVKEIATPTHWSKLDPKAMKVNDLRKELESRALSSKGLKSQLIARLTKQLKIEEQKEEQKELEKSEKEEEDEDD-KKSEDDKEEEERKRQEEVERQRQERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKDKEKKSKKE-ERKDKKEEREDDIDEPKPKRRKSGDDKDKKEDRDERKKEEKRKDDSKDDDETEEDNNQDEYDPMEAEEAEE-EEDDREEEEVNKRDDKRDVS--RYCKDRPSKDKEKEKPQMVTVNRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDGESHDEPESLQGDTTLGNRLLLPTPTVKQESKDGEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDGKTILNLENSNKSLSGELREVKKDLGQLQENLKVSENMNLQFENQLNKTLRNLSTVMDDIHTVLKKDNVKNEDRDQKSKENGSSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CH18-1", "uniprot_id": "CCAR1_MOUSE", "id": "Q8CH18-1", "name": "Cell division cycle and apoptosis regulator protein 1", "aln": "MAQFGGQKNPPWATQFTATAVSQP------------AALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPANYQLT-QTAALQQQ-----AAAVLQQ--------QYSQ-----------------PQQALYSVQQQLQQPQQTILTQPAVALPTSLSLSTPQPAAQITVSYPTPRSS-QQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLGAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQ------------------------------------------NQSQTQPLLKTPTAVIQPIVPQTTFGVQAQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQK-----AGLLQPPVRIVSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDR---------------SRERDRERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNMAVLDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQDLRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPNPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKKADGEQDEEEKDDGEVKEIATPTHWSKLDPKAMKVNDLRKELESRALSSKGLKSQLIARLTKQLKIEEQKEEQKELEKSEKEEEDEDD-KKSEDDKEEEERKRQEEVERQRQERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKDKEKKSKKE-ERKDKKEEREDDIDEPKPKRRKSGDDKDKKEDRDERKKEEKRKDDSKDDDETEEDNNQDEYDPMEAEEAED-EDDDREEEEVK-RDDKRDVS--RYCKDRPAKDKEKEKPQMVTVNRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDDENHEESEALQED-MLGNRLLLPTPTIKQESKDGEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDGKTILNLENSNKSLSGELREVKKDLGQLQENLEVSENMNLQFENQLNKTLRNLSTVMDDIHTVLKKDNVKSEDRDEKSKENGSGV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IX12-1", "uniprot_id": "CCAR1_HUMAN", "id": "Q8IX12-1", "name": "Cell division cycle and apoptosis regulator protein 1", "aln": "MAQFGGQKNPPWATQFTATAVSQP------------AALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPANYQLT-QTAALQQQAAA--AAAALQQ--------QYSQ-----------------PQQALYSVQQQLQQPQQTLLTQPAVALPTSLSLSTPQPTAQITVSYPTPRSS-QQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQ------------------------------------------NQSQTQPLLKTPPAVLQPIAPQTTFGVQTQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQK-----AGLLQPPVRIVSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDR---------------SRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNMAILDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDD-RKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKD-ERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAED-EEDDRDEEEMTKRDDKRDIN--RYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQED-MLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKDQKSKENGASV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B3E5-1", "uniprot_id": "A0A8M2B3E5_DANRE", "id": "A0A8M2B3E5-1", "name": "Cell division cycle and apoptosis regulator protein 1", "aln": "MAQFGGQKNPPWAAQFAATAVSQPGHTGQSLDLNSLHSLGVQQQSLLGASP-MYTQQSALAAASLNSQSAANYQLSQQTAALQQQAAAAAAAAALQQSQINSALQQYQQQQQQQQQPPQAPPPQPPPQQTLYNVPHQLPQPQQALLSQPPVALPTSLSLSNPQQTAQITVSYPTPRSSHQQQTQPQKQRVFTGVVSKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEAVYNPNMPFKWNAQRIQTLPQLPNQTHQPPQPLPQVSPQLSSFYTDAGMQRYSDLHSAVDSRQNSQPQVPNMMKPGPTMLQSLPPPTTFSVPAQGPPPSLLQAQLSAASLAPLLQNPPQPLLPQPPPKDSVFSGGLLQPPVRMMPQPQQVRRVEPSPRFPNRSDRPELILRKDDRRSALKHTPDSQCFSRRSRERERERRRSRERSPMRKRSRDRSPRRER--SPRRPRRVVPRYTVQFSKFSLDGYNCDMMELRRRYQSLYIPSDFFNAVFTWVDAFPLSRPFTFGNYCNFHIMHKEVDSLVKNTAVLDPPDANHTYSAKVMLLANPSLDELYHKSCALSEDPAELRDSFQHPARLIKFLVGMRGKDEAMAIGGHWSPSLDGADPEHDASVLIKTAVRCCKALTGIDLSLCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFLPDVWHCLPTRSEWEELSRGLKEQLAEKLLAERKEADGEQEEEDKDEDDSKEVTTPTHWSKLDPKSMKVSDLRKELESRSLSSKGLKSQLIARLTKQLKVEEQVEESKEPEKPEPPSVEEDESCRLEDDREEEERKRQEEQERQRRERRYVLPDEPTIIVHPNWAAKNGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGYRIYKALASLPTKDEKKDKKERAKKEAERRDIKKERDEDNGEPVTKRIREEDDKRKDEEKERGIKREESKDDD-DNEDGSSNNNADEYDPLEAEDADDYDDDDKDDEDSNGRDRRDDRRDDRKSKDRSSKDKDEKKRQMVTFNKDLLMAFVYFDQSHCGYLLEKDLEEIMYTLGLHLSRAQVKKLLNKPLVKESCHYRKLTDRPKDEPCPALISEAHIDNLLGNQILLTSQKIKREPDESGESGSLIVYKGALVDVGSMMQKLEKSEKTREDIEQKLMQQDVKMEEDSKHISELEAANRSLQKELDDVKNTLRETESKLTASDQRKGRFEQQLHSTVSSLDTIKKELQGVLAN-NDRSEDADHKTQANGSDE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************:**:******* :***** ******* :****:*****.*.:*:.*****: ******** ***.*** **.* ***:**.* : **.**********.** :************* ****************:*****************.*****************.******************: .*.*. ::*. .:::*.: * ***.* :* * ******:****::****. ***** ** * .********::.*** .**::*..**..*.** : : .:.* * ****:*********** *****:******* **** ***************** .***********.********:* ************* :******::**:**:** ** *:******:* *******:*.**:::********:*** :***.*******:******:******************.:**:*.*******:************:**********************************:************** **** *:**.*** .***:*****:**:**:.: **::***********:***.*********:*******************:*** **.** **.* . ::*: : ***:********** ****:****:*****:**********.******************************************** ****:* *** *::**:*.:::**: **:* *:**::: .** .** :. *** *.*:::. *.:: ***. *::: ..:** *****:***:*:: ::**:::*: . ** : * * .*:*.:***:::* **:*.*:*************************:****************** :::***.****** .** . : * ***::**.: .:*:*..: *. .****:**:*****::********.* ::**** : * :** * * :** :*:**. ** :**: * : :.:* *:: : :**:*::.*: .*.*: .::: ** : * :.** *.*:: **:. ", "identical_positions": 788, "similar_positions": 232, "identity": "62.59%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1473", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7F0-1", "uniprot_id": "D4A7F0_RAT", "id": "D4A7F0-1", "name": "E3 ubiquitin-protein ligase", "aln": "---------------------------------------------------------------------------------------------------MAAAAAAAVGGPQPPQPEVSAQGPTLDKAATAAHLKAALSRPDNRAGAEELQALLERVLNAERPLARAAGGE------EAAGGGS--PGEAEEDALEWCKCLLAGGGGYDEFCAAVRAYDPAALCGLVWTANFVAYRCRTCGISPCMSLCAECFHQGDHTGHDFNMFRSQAGGACDCGDSNVMRESGFCRRHQIKSSSNIPCVPKDLLMMSEFVLPRFIFCLIQYLREGYNEPAADTPSEKDLNKVLQLLEPQISFLEDLTKTGGAMRAVLTQVLTNQQSYKDLTAGLGENTCAKKSHEKYLIALKSSGLTYPEDKLVYG--IQEPSAGTSTLAAQGFAGATGTLGQIDSSDEEDQDGSQGLGKRKRVKLSSGTKDQSIMDVLKHKSFLEELLFWTIKYEFPQKMVTFLLNMLPDQEYKVAFTKTFVQHYAFIMKTLKKSHESDTMSNRIVHISVQLFSNEELARQVTEECQLLDIMVTVLLYMMESCLIKSELQDEENSLHVVVNCGEALLKNNTYWPLVSDFINILSHQSVAKRFLEDHGLLVTWMNFVSFFQGMNLNKRELNEHVEFESQTYYAAFAAELEACAQPMWGLLSHCKVRETQEYTRNVVRYCLEALQDWFDAINFVDE----PAPNQVTFHLPLHRYYAMFLSKAVKCQELDLDSLLPDQ-EMLMKLMIHPLQIQASLAEIHSNMWVRNGLQIKGQAMTYVQSHFCNSMIDPDIYLLQVCASRLDPDYFISSVFERFKVVDLLTMASQHHNMVLDVEHERSMLEGALTFLVILLSLRLHLGMSDDEILRAEMVAQLCMNDRTHSSLLDLIPENPNPKSGIIPGSYSFESVLSAVADFKAPVFEPGGSMQQGMYTPKAEVWDQEFDPVMVILRTVYRRDVQSAMDRYTAFLKQSGKFS--GNPWPPYKKRTSLHP--SYKGLMRLLHCKTLHIVLFTLLYKILMDHQNLSEHVLCMVLYLIELGLEDSAEDDS------------EEEVSMGGPERCHDS----------WFPGSNLVSNMRHFINYVRVRVP----------------------ETAPELKR--------DSLASTSSDGLGSLQNSGTAQVFSLVAERRK--------------KFQEIINRNNSE-------------------------------------------------------------ANQVVRPK-TPSKWSAPGSAPQ-------------------------------------------------------------------LTTAILEIKESILSLLIKLHHKLSGKQNSYYPP----------------------WLDDIEVLIQPEIPKYSH------------GDGITAVERILLKAAVQSRMNKRIIEEICRKVTPPVPPKKITTAEKKTLDKEERRQKARERQQKLLAEFASRQKSFMETAMDVDSPENDIPMEITTA---EPQVSEAVYDCVICGQSGPSSEDRPTGLVVLLQASSVLGQCRDNVEPKKLPITEEEQ--IYPWDTCAAVHDVRLSLLQRYFKDSSCLLAVSIGWEGGVYVQTCGHTLHIDCHKSYMESLRNDQVLQGFSVDKGEFTCPLCRQFANSVLPCYPGSNVENNLWQRPSNKSTQDLIKEVEELQGRPGAFPS------------ETNLSKEMESVMKDIKNTTQKKYRDYSKTPGSPDNDFLFMYSVARTNLELELIHRGGSLCSGGAS-TAGKRSCLNQLFHVLALHMRLYTIDSEYNPWKKLTHLVEDMNSQVGSEDQQPEVPVLYHDVTSLLLIQILMMPQPLQKEHFTCIVKVLFTLLYTQALAALSVKGTEEDR-------------------------------SAWKHLGALKKDTCDAEKSYEVLLG----------------------FVISELSKGKLYCEEGAQECTMVSPIAWSPESMERYIQDFCLPFLRISSLLQHHLFGEDLPSCQEE-EEFSVLASCLGLLPTFYQTDHPFISASCLDWPVAAFDIITQWCFEIRSFTERHAEQGKALLI-QESRWKLPHLLQLPENYNTIFQYYHRKTCSVCTKVPKDPAVCLVCGAFVCLKGLCCKQQSYCECVLHSQNCGAGTGIFLLINASVIIIIRGHRFCLWGSVYLDAHGEEDRDLRRGKPLYICEERYRVLEQQWVSHTFDHINKRWGPHYNGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5U430-1", "uniprot_id": "UBR3_MOUSE", "id": "Q5U430-1", "name": "E3 ubiquitin-protein ligase UBR3", "aln": "--------------------------------------------------------------------------------------------------MAAAAAAAAVGDPQPPQPEAPAQGLALDKAATAAHLKAALSRPDNRAGAEELQALLERVLNAERPLAGAAGGE------EAAGGGGGGPGEAEEDALEWCKCLLAGGGGYEEFCAAVRAYDPAALCGLVWTANFVAYRCRTCGISPCMSLCAECFHQGDHTGHDFNMFRSQAGGACDCGDSNVMRESGFCRRHQIKSSSNIPCVPKDLLMMSEFVLPRFIFCLIQYLREGYNEPAADAPSEKDLNKVLQLLEPQISFLEDLTKMGGAMRSVLTQVLTNQQNYKDLTAGLGENACAKKSHEKYLIALKSSGLTYPEDKLVYG--VQEPAAGTSTLAAQGFAGATGTLGQIDSSDEEDQDGSQGLGKRKRVKLSSGTKDQSIMDVLKHKSFLEELLFWTIKYEFPQKMVTFLLNMLPDQEYKVAFTKTFVQHYAFIMKTLKKSHESDTMSNRIVHISVQLFSNEELARQVTEECQLLDIMVTVLLYMMESCLIKSELQDEENSLHVVVNCGEALLKNNTYWPLVSDFINILSHQSVAQRFLEDHGLLVTWMNFVSFFQGMNLNKRELNEHVEFESQTYYAAFAAELEACAQPMWGLLSHCKVRETQEYTRNVVRYCLEALQDWFDAINFVDE----PAPNQVTFHLPLHRYYAMFLSKAVKCQELDLDSLLPDQ-EMLMKLMIHPLQIQASLAEIHSNMWVRNGLQIKGQAMTYVQSHFCNSMIDPDIYLLQVCASRLDPDYFISSVFERFKVVDLLTMASQHHNMVLDVEHERSMLEGALTFLVILLSLRLHLGMSDDDILRAEMVAQLCMNDRTHSSLLDLIPENPNPKSGIIPGSYSFESVLSAVADFRAPIFEPGGSMQQGMYTPKAEVWDQEFDPVMVILRTVYRRDVQSAMDRYTAFLKQSGKFP--GNPWPPYKKRTSLHP--SYKGLMRLLHCKTLHIVLFTLLYKILMDHQNLSEHVLCMVLYLIELGLENSADDDS------------EEEVSMGGPERCHDS----------WFPGSNLVSNMRHFINYVRVRVP----------------------ETAPELKR--------DPLASTSSDALDSLQNSGTAQVFSLVAERRK--------------KFQEIINRSNSE-------------------------------------------------------------ANQVVRPK-IPSKWSAPGSSPQ-------------------------------------------------------------------LTTAILEIKESILSLLIKLHHKLSGKQNSYYPP----------------------WLDDIEVLIQPEIPKYNH------------GDGITAVERILLKAAVQSRMNKRIIEEICRKVTPPVPPKKITAAEKKTLDKEERRQKARERQQKLLAEFASRQKSFMETAMDVDSPENDIPMEITTA---EPQVSEAVYDCVICGQSGPSSEDRPTGLVVLLQASSVLGQCRDNAEPKKLPIAEEEQ--IYPWDTCAAVHDVRLSLLQRYFKDSSCLLAVSIGWEGGVYVQTCGHTLHIDCHKSYMESLRNDQVLQGFSVDKGEFTCPLCRQFANSVLPCYPGSNVENNLWQRPCNKSTQDLIKEVEELQGRPGAFPS------------ETNLSKEMESVMKDIKNTTQKKYRDYSKTPGSPDNEFLFMYSVARTNLELELIHRGGSLCSGGPS-TAGKRSCLNQLFHVLALHMRLYTIDSEYNPWKKLTQLVEDMNSQVGNEDQQPEVPILYHDVTSLLLIQILMMPQPLRKEHFTCIVKVLFTLLYTQALAALSVKGTEEDR-------------------------------SAWKHAGALRKDTCDAEKCYEVLLS----------------------FVISELSKGKLYYEEGAQECAMVSPIAWSPESMERYIQDFCLPFLRVSSLLQHHLFGEDLPSCQEE-EEFSVLASCLGLLPTFYQTDHPFISASCLDWPVAAFDIITQWCFEITSFTERHAEQGKALLI-QESRWKLPHLLQLPENYNTIFQYYHRKTCSVCTKVPKDPAVCLVCGTFVCLKGLCCKQQSYCECVLHSQNCGAGTGIFLLINASVIIIIRGHRFCLWGSVYLDAHGEEDRDLRRGKPLYICEERYRVLEQQWVSHTFDHINKRWGPHYNGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZT12-1", "uniprot_id": "UBR3_HUMAN", "id": "Q6ZT12-1", "name": "E3 ubiquitin-protein ligase UBR3", "aln": "---------------------------------------------------------------------------------------------------MAAAAAAAVGGQQPSQPELPAPGLALDKAATAAHLKAALSRPDNRAGAEELQALLERVLSAERPLAAAAGGED-----AAAAGGGGGPGAAEEEALEWCKCLLAGGGGYDEFCAAVRAYDPAALCGLVWTANFVAYRCRTCGISPCMSLCAECFHQGDHTGHDFNMFRSQAGGACDCGDSNVMRESGFCKRHQIKSSSNIPCVPKDLLMMSEFVLPRFIFCLIQYLREGYNEPAADGPSEKDLNKVLQLLEPQISFLEDLTKMGGAMRSVLTQVLTNQQNYKDLTSGLGENACVKKSHEKYLIALKSSGLTYPEDKLVYG--VQEPSAGTSSLAVQGFIGATGTLGQVDSSDEDDQDGSQGLGKRKRVKLSSGTKDQSIMDVLKHKSFLEELLFWTIKYEFPQKMVTFLLNMLPDQEYKVAFTKTFVQHYAFIMKTLKKSHESDTMSNRIVHISVQLFSNEELARQVTEECQLLDIMVTVLLYMMESCLIKSELQDEENSLHVVVNCGEALLKNNTYWPLVSDFINILSHQSVAKRFLEDHGLLVTWMNFVSFFQGMNLNKRELNEHVEFESQTYYAAFAAELEACAQPMWGLLSHCKVRETQEYTRNVVRYCLEALQDWFDAINFVDE----PAPNQVTFHLPLHRYYAMFLSKAVKCQELDLDSVLPDQ-EMLMKLMIHPLQIQASLAEIHSNMWVRNGLQIKGQAMTYVQSHFCNSMIDPDIYLLQVCASRLDPDYFISSVFERFKVVDLLTMASQHQNTVLDAEHERSMLEGALTFLVILLSLRLHLGMSDDEILRAEMVAQLCMNDRTHSSLLDLIPENPNPKSGIIPGSYSFESVLSAVADFKAPVFEPGGSMQQGMYTPKAEVWDQEFDPVMVILRTVYRRDVQSAMDRYTAFLKQSGKFP--GNPWPPYKKRTSLHP--SYKGLMRLLHCKTLHIVLFTLLYKILMDHQNLSEHVLCMVLYLIELGLENSAEEES------------DEEASVGGPERCHDS----------WFPGSNLVSNMRHFINYVRVRVP----------------------ETAPEVKR--------DSPASTSSDNLGSLQNSGTAQVFSLVAERRK--------------KFQEIINRSSSE-------------------------------------------------------------ANQVVRPK-TSSKWSAPGSAPQ-------------------------------------------------------------------LTTAILEIKESILSLLIKLHHKLSGKQNSYYPP----------------------WLDDIEILIQPEIPKYSH------------GDGITAVERILLKAASQSRMNKRIIEEICRKVTPPVPPKKVTAAEKKTLDKEERRQKARERQQKLLAEFASRQKSFMETAMDVDSPENDIPMEITTA---EPQVSEAVYDCVICGQSGPSSEDRPTGLVVLLQASSVLGQCRDNVEPKKLPISEEEQ--IYPWDTCAAVHDVRLSLLQRYFKDSSCLLAVSIGWEGGVYVQTCGHTLHIDCHKSYMESLRNDQVLQGFSVDKGEFTCPLCRQFANSVLPCYPGSNVENNPWQRPSNKSIQDLIKEVEELQGRPGAFPS------------ETNLSKEMESVMKDIKNTTQKKYRDYSKTPGSPDNDFLFMYSVARTNLELELIHRGGNLCSGGAS-TAGKRSCLNQLFHVLALHMRLYSIDSEYNPWRKLTQL-EEMNPQLGYEEQQPEVPILYHDVTSLLLIQILMMPQPLRKDHFTCIVKVLFTLLYTQALAALSVKCSEEDR-------------------------------SAWKHAGALKKSTCDAEKSYEVLLS----------------------FVISELFKGKLYHEEGTQECAMVNPIAWSPESMEKCLQDFCLPFLRITSLLQHHLFGEDLPSCQEE-EEFSVLASCLGLLPTFYQTEHPFISASCLDWPVPAFDIITQWCFEIKSFTERHAEQGKALLI-QESKWKLPHLLQLPENYNTIFQYYHRKTCSVCTKVPKDPAVCLVCGTFVCLKGLCCKQQSYCECVLHSQNCGAGTGIFLLINASVIIIIRGHRFCLWGSVYLDAHGEEDRDLRRGKPLYICKERYKVLEQQWISHTFDHINKRWGPHYNGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QJX5-1", "uniprot_id": "UBR3_DANRE", "id": "F1QJX5-1", "name": "E3 ubiquitin-protein ligase ubr3", "aln": "--------------------------------------------------------------------------------------------------------------------MMAASLLRRDKKSTAAHLKADLKRTDNSSGLRQLQELLDSVLNPER--------------------------GSDPEALDWCKWLLAGGDGFDEFCRTVRSYDNATLCGLVWTANFVAYRCRTCGISPCMSLCAECFNNGDHTGHDFNMFRSQAGGACDCGDGNVMRESGFCNRHRLKTGENVPSVPRDLLLMSEMVLPRFIITIIQYLRDGYTEPES--AADRDLQKVLQQLDPHISFLEELTKMGGAMRTVLTKILTDQQTFKELSMGQEDNVYAKKNYEKYLSALKSSGLVSVEEKGAAGGAGDGTSDAAAGAGALSLLGATATASLDDSSKEEDQDGLQGVGQRKRVKLSSSTKDPSIMDTLKHKCFLEELLFWTIKYEFPQKMVTFLLNMLPDQDYKITFTKTFVQHYAFIMKTLMKSHESDTMSNRIVHISVQLFSNEELARHVTEECQLLDIMVTVLLYMMESCLIKSELQDEENNRHVVVNCGEALLKNNTYWPLVSDFINILSHQSVAKRFLEDHSLLLLWMSFVSFFQGMNLNKRELNEHVEFESQTYYAAFAAELEACAQPMWGLLTHCKVKETQDYTKTVVRYCLETLQMWFDAIGFVDE----PSLNQLTFHLPLHRYYAMFLSKGVKCQGLDLDSLLPDQ-EMLMKIMVHPLQIQASLSEIHSNMWVRNGLQIKGQAMTYVQSHFCNSMIDPDIYLLQVCASRLDPDYFISSVFERFKVVDLLTMASQHQNAVLDSEQERPMLEGALTFLVILCSLRIHLGMSDDEILRAEMVSQLCMNDRTHSSLLDLIPENPNPKSGVVPGSCSFEEMLSGVADFKAPVFEPGGSMQQGMYTPKAEVWEKEFDPIMVILRTVYRRDVQSAMDRYSAFLKQSGVHT--GNPWPPYKERTPLHP--CYKGLVRLLHCKTLHIVIFTLLYKIWMDHQNMSEHVLCMVLYLIELGLDNQVQDDK------------VEEEPC-IEEHCHDS----------WFPGTSLLSNLHHVINFVRVRVP----------------------ETAPEVERKRERERERETPPSTSSESATFGQNLREAQVFSLVAERRR--------------KFQEIINRSNHE-------------------------------------------------------------ASQAVRPKSSASRWLPPGTPPQ-------------------------------------------------------------------LVTEILEIRESMLSLLVKLHQKLSAKQNSLSLS----------------------WLAEVDP------AHHAH------------GDGLTAIERILAKASARSRHSKRCLQEICGKVCPPIPPKKISPGDKKSMDKEERRQRARERQQKLLAEFASRQKSFMETAMDVESPEADAVMDVSSE---ESLDSEVLYDCVICGQSGPSTEDRPTGLVVLLQASSVLGHRCRSDMPKRLPTTDEEH--IYPEDTCGATHDVRLSLMQRYFKDSSCLQSVSIGWDGGVYVQTCGHTLHIDCHKSYMESLRNDQVLQGISVDKGEFTCPLCRQFANSVLPCRPGRGMETGAWHAPSTKSMSTLVKEVEDLQEQLGIFPVRASIKQRDPILIESNLSKEMESVIKDIKNTTQKKYMDYGKNPGSPDNDFLFMYSVARTNLELELVHRGGNLCSGGAS-AAAKRSCLNQLFHVLAMHMRLYSIDSAYNPWTRLTLSTQSRENEYCDEER-PEVPMLFRDVPSLLIIFILTMPQPLRKEHFTCVVKVLYSLQFTQALAALSIRFSREER-------------------------------LAWSNTGAAKKNLPNSDKSWESLLG----------------------HMISELTKAKDVYDTNSEETSALSSSVWSPQSIEFRLQQFCLPFLRLSCLLQHHLYGDSLPGCLVE-EEFSLLTRCLGLAAS-VQCSGSMSSAACLEWNISAFDLISQWCSEVVALSDTPSQQSASLLG-QDPQWAAPRLLQLPDNYNTIFQYYHRKSCSSCGKTPKDPALCLVCGAFVCLKGHCCKQQGVCECVLHSQHCGAATGIFLLINASVIIIIRGHRFCLWGSVYLDAHGEEDRDLRRGKPLYLCEERYRVLEQQWVAHTFDHINKRWGPHYNGL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3M3-1", "uniprot_id": "UBR3_DROME", "id": "Q9W3M3-1", "name": "E3 ubiquitin-protein ligase Ubr3", "aln": "MDEDDNLSNADISIDDEEVVREQTHHPPMQEDQELDNEDGSSDVDLSSVYVVPPIVSAPSPASVRIAGGSTIGGGGVAAGAVPTTTDNSHSPFHDWDSSVAAAAAPPPPPPRTGPTTTTSSGTAAESGAASALSDDAGAKPSFFFGASSFSLRSRKEVAALINTECCRGSPTPDLDSIMDTLFNPGTPIDNLDNIEWIRWLIAGGRTPQEFVKIVRSYDNHAKCGLVWVPHVVAYRCRTCGISPCMSICRDCFKKGNHTNHDFNMFLSQAGGACDCGDTSVMKAEGFCSDHGINNRVNRDPVPNNLLAVAEAIMPKLLFRLLQHFREHSDTPLEVQAITS------YSCEEFANMLIDLNNMGEIMRKVMTRTLIN----PEVYAFFMEAPCQDTRNGRFLKANREK-----------------------------YEDAVNRFPNPEPPDE--YRDLPALG-----------------DKLVHTTLLEEFIFWTFKFEFPQTLVCFLLNMLPDQDYKEHLTRTFVMHYSRIPSVLEMSRDPDTLSNRVVHMSVQLFSNESLALKMVNELSLLHVMIISLKLMMSKILIQNTLHDPNKNFHFVIDCTRQVMKDHCYWPLVSDFNNVLSHESVALVFLRDDNLIDMWFQFLQMLQGMNVNVRETASHVEFEPNSYYAAFSCELEASAYPMWSIISHLQDGTHAHLAKKIINYCVTTLHEWLDSIYFMEARLSMEEMMQASFHFPLHRYLAAFVCQAVTKMGISLNDVLPSRPYLLPLLMIHPLRVQSFFYEILAGKWVRNGLQIKGQAMTYIQANFCNSMADMDLFFLQICATNLPQYFFLQNTIELFDVGQWLETAPLKQ---PQKAEQSSMLEGFLTFLATLVTSRTNLGNDEATQCIIEISALLATENKTHSQLLELMPE----RSGNVH-TKNFETFLKKLSVYKAPSSGSE-NLEQGLFTPIDEVWEKHYDPLHVLLRAVHRRDFQSSLDRFTNYVKSKDKMPASGNLWPPFRLPHALPATSSFSDPCKILNSRIFHSTILSIFFRAVHTRD-VSEHLLALAVFLLEIAVETSDDVGSGTGDRAPPALAAVVESSSGPGYHGYGTGRHEPPKLFHCYPTDNLSCNLRHVVKKVSLKSRDPQVITSSYRSNPFYSDLDFEVEADPEQSMRMIGQGDPEGDEATGGAGLGMGAHSRRNVSQALVPMRVPGMEVALPPDLSVVAETGVVIRQDSNEDDLLREGNHAMDMSPPAALDFHFPLQQITLPESGMEVAIRRDLLLAETNNMGAIAGGAGGGANASATPPAGASNEMFSPTTPTGSGMLLPFQRVQPVAVPSSGNMDIVPSNAMGAGGSFTSGVSGSGTGRRMNYETGGARKRSVDIAIGGSNKDELHLDESILSLLLKLHSQLSGTLDSFSLSDGEDQSSDDDSTMDVDCNEASTSMAAAESTALAERGRSKRNYKNIHVSSSRIGDGPFFIGNLLRKIAKQDEQCAQSIDDIRARLWPNQREKQAEAKAREAKEKEERRKKARERQQKMMQDFANKQKLFMQSAAASSSGMGYGPEDEDDEELYEEQPREKEYDCIICNCTTPSTESNPIGLVVLVESSGIVGHRRRIAERLPLPINAEDESRLAHTTRLAAEFNRRTELLSLKFGDESWYLSNNMAYDNGVHVQSCGHHVHLSCLEAYLKTLYTTQRQP--VQDRGEFYCPVCRQLSNSVLPLSPQLDRPTHLVRS-GNQPFERLVADLTDLIKENETIPQ------------PTKLTEAMGHAMEVMTNIAQRKVKCSSITFR---KLFIFVTSIARTNLEAEIIQRGGSLCTANATRYKPKRECIVPLLHVLSVHVRVLVEWPLWSSWASLAGLPVTATEPLP-AHCLELIPSILADPIALLLKFILLAPLQLDQDYFTCMVKVMYNLLYYQIVVQLCVTLTDLECDHIVKVYGSTSVGSDNSAAESQQQESAAGTTNNRRRAGQQQQSSSQLGKAMALVLSQTNDLVHLRRDCIPSTSSSAAASAAGSSSTTSTNHGASAATASSATTIEVNLKSMELQLQALCLPFLRVAALLRQHLYRHEMPEISAPGLEFVRLVYYLELVTDSMDWDCFNASKGLCFIPGTETTLPQFWCQQLMEVRPPADTVRELVLINQHSLWQQPRLLELPREYERLFTYYHERPCLNCYKVPKESSICLLCGTIVCLKQNCCAENDCCEAVRHTLSCGGGIGIFLVVTSTYIIVIRGRRACLWGSLYLDDFDEEDRDLKRGKPLYLSKDRFNLLESQWLSHKFAHTKHTWVFHRDLL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :. :::* . :.. * .:. : . : : ::* : *:*** :** **:** : *****..:.***************:* :**::*:**.****** *********** .**: .*** * ::. * **.:** ::* ::*:::: ::*::*: * . : .:* :*.: * ** *:*: * : :: : .. ::* * :.. .*. :...* . .:* * * *. :***::***:*:****.:* *********:** :*:*** **: * ..* *::.**:***:**:********.** ::.:* .**.:*: * **.. **:. *:* ::. *.*::* . ::*:: ******** *:***:*** **.*..*: *:.*:.::****:* ** .*****.::*****:.****.* ***.:::* : . ::.::.**: :*: *:*:* *:: * :**:***** * *:.:.*. :.*:.:**.: :* :*:***::*: : ** :. ***************:*::***** * *:::**:**:.* :*:...:* *.* : * *. :: : .: .**** ****. * : * :** .: *: : *. :::***.**:*:** :** : : .** .*. :: ::** . .::**::** ***::.:**: *:**:*:***.**::**:: ::*... . ** ***:: .* . .:.. ::*:.: :* .::::::: :: :***:*.:.::*:*:.:: . : . * . : :.: :* .* .*::*.:: * :: *: ** . : :*.. : :**. * : :*.:.. * *. . * .*. . :.* . *.: **:****:*** :**.. :* . : : : : *** : .:* * : :.. : :::* :: * *: . ::: :*****::*******:: :**.:** **::* .* : * * ***:**. : **:*..* *****:::*.::*: ** *:. : .* .: * .*:. * *.* : .:.::.**:**:*** :*:.* ::*:::* . * *:*** **:***::***** * . . : .:. . *: :: :* . :* ::*:: * .:: :.* :*:* . . : *:*: *:****** *:::***.**:...: **.*: *:***::*:*: . :..* *: . :* : * :**: ** * * :::***:***::.* : * :. *.: : : . * ::. : *. :*. .. . . .: : .. . :*:* :* :******::.**::**: ..:* ** *. * * . : . * . . : ** :: . :* *.. * *:**:** :*: :* ***.:.* * *.**:.::**:**::**** ** ::. **.* *: **.. ****::.:: **:***:* *****:*** ..******:******:.::*:.:**.**::*.* * :: * * : *", "identical_positions": 591, "similar_positions": 592, "identity": "25.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1495", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHQ8-1", "uniprot_id": "D3ZHQ8_RAT", "id": "D3ZHQ8-1", "name": "", "aln": "-------------MEVVGP----TAVPQKLSRKKYMALRKKEKRKKRRQELARLRDAELSQKEEEEDPLGEEKRLEEERLLEA-ERQRLHEEWLLREEKAQEEFRAKKRKEEAARKRKEELERKLKAEWEEQQRKEREEEEQKQQEKREREEAAQKRLDQAENELENGGTWQNPEPPTDIRVLEKDRANCPFYSKTGACRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQ-CRRDDYD-PDSSLEYSEEETYQQFLDFYYDVLPEFKSVGKVIQFKVSCNLEPHLRGNVYVQYQSEEDCQAAFSVFNGRWYAGRQLQCEFCPVTRWKMAICGLFEVQQCPRGKHCNFLHVFRNPNNEYREANRDIYLSPDWTSSSFAKSSERRE----RASHYDEYYGRSRRRR----SPSPGLSYKRNGESDRKSSSNHRVKKSHKHGMKNRERHSSRSRRRKRDHSLGPWSQSRRSRHSRSRSHSQSRSRSSSRSRSCGRGRGWSHSRSHSRSRKRSRNRSRSRSRNRNRNRNRKRNQSRSWSHSHSHSRSSSRSRSPGRRRSGSRDKTTQSPKSK-------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62377-1", "uniprot_id": "U2AFM_MOUSE", "id": "Q62377-1", "name": "U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2", "aln": "-------------METAGATADATAGPQKLSRKKYLALRKKERRKRRRQALARLREAELAQKEEEEDPLAEEKRLEEERLLEE-ERQRLHEEWLLREEKAQEEFRAKKKKEEEARKRKEELERKLKAEWEEQQRKEREEEEQKRQEKREREEAVQKMLDQAENELENGGTWQNPEPPMDIRVLEKDRANCPFYSKTGACRFGDRCSRKHNFPTSSPTLLIKGMFTTFGMEQ-CRRDDYD-PDSSLEFSEEEIYQQFLDFYYDVLPEFKSVGKVIQFKVSCNLEPHLRGNVYVQYQSEEDCQAAFSVFNGRWYAGRQLQCEFCPVTRWKMAICGLFEVQQCPRGKHCNFLHVFRNPNNEYRDANRDLYPSPDWTSSSFGKNSERRE----RASHYDEYYGRSRRRRR---SPSPDF-YKRNGESDRKSSSRHRVKKSHRYGMKSRERRSSPSRRRK-DHSPGPWE-PEQEEPPQQESQSQPQPQPQSDP----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15696-1", "uniprot_id": "U2AFM_HUMAN", "id": "Q15696-1", "name": "U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2", "aln": "-------------MAAPEK----MTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLER-ERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRANCPFYSKTGACRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQ-CRRDDYD-PDASLEYSEEETYQQFLDFYEDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFNGRWYAGRQLQCEFCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYLSPDRTGSSFGKNSERRE----RMGHHDDYYSRLRGRR----NPSPDHSYKRNGESERKSSR-HRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRS----------------------------------------------------------RSRGRRRSGNRDRTVQSPKSK-------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q15695-1", "uniprot_id": "U2AFL_HUMAN", "id": "Q15695-1", "name": "U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1", "aln": "-------MAALEKMTFPKK----MTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQ-EEEEDTFIEEQQLEEEKLLER-ERERLHEEWLLREQKAQEEFRIKKEKEEAAKKWLEEQERKLKEQWKEQQRKEREEEEQKQQEKKEKEEAVQKMLDQAENDLENSTTWQNPEPPVDFRVMEKDRANCPFYSKTGACRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQ-CRRDDYD-PDASLEYSEEETYQQFLDFYEDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFNGRWYAGRQLQCEFCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYLSSDQTGSSFGKNSERRE----KMGHHDHYYSRQRGRR----NPSPDHTYKRNGESERKKSS-HRGKKSHKRTSKSRERHNSPSRGRNRHRSWDQGR--------RSQSRRSHRSRSQSSSRC----------------------------------------------------------RSRGRRKSGNRDRTVQSPQSK-------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64707-1", "uniprot_id": "U2AFL_MOUSE", "id": "Q64707-1", "name": "U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2-like", "aln": "-------------MASRQT-----AIPEKLSRKQYKAAMKKEKRKKRRQKMARLR--ALEAPPEEDDDVSANEELA-ERLLEI-ERQRLHEEWLLREEKAQEEFRIKKKKEEAARKQKEEQERQIKAEWEEQQKKQREEEEQKLQEKREREEAVQKMLDQAENER----IWQNPEPPKDLR-LEKYRPSCPFYNKTGACRFGNRCSRKHDFPTSSPTLLVKSMFTTFGMEQ-CRRDDYD-SDANLEYSEEETYQQFLDFYHDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFNGRWYAGRQLQCEFCPVTRWKVAICGLFEMQKCPKGKHCNFLHVFRNPNNEFREANRDIYMSPPAWTGSSGKNSDRRE----RKDHHEEYYSKSRSYH-----SGSYHSSKRNRESER--KSPHRWKKSHKQTTKSHERHSSR-RGREEDSSPGPQS----------QSHRT-------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9Q815-1", "uniprot_id": "A0A8M9Q815_DANRE", "id": "A0A8M9Q815-1", "name": "", "aln": "MTEKDCCSIQTETQDSENRLNMCETPSVVLSHKQRRAALKRERRKRKRQALAKIKEADNNLQNEELQSEAED---EDKLKVDE-ESERLHQEWMERERIAQEEFRLKKEREDAAQQRKEEEERKIKEEWEEQQRKDKEEREHKEQEKREREEAVQKMLDQAESQLENGGPWKNPDAPKDYG-TEKDKANCPFFLKTGACRFGDRCSRKHDHPASSCTLMVRGMFVSFGMEQ-SRRDDYD-TDASLEYSEEELHQQFLDFYEDALPEFKNAGRVVQFKVSCNFEPHLRGNVYVQYETEEQCKEAFVMFNGRWYAGRQLQCEFSPVTRWKTAICGLFDRRKCPKGKHCNFLHVFRNPDNEFWEADRDLHMSPDRGGGFSARHMSGRDGMWSQCGNSSERFQRRRTDRRSHSRERYSYRGRRSRSRERRSRSRERRSRSRERRSRSRERQNRNRERQSRSRSREKRKSENSIRRSTSQREQSRRSRSRSQSRDRLKQSDSADSEKKMSKSNSPEHVSKNGSVKRKSHRKESQSPENTDRMDAHHHKHSKKSKKKKKGKKKHKRKKSKSRSSSSSAGSDEESRIKGFEETPSKSQASVEECPAAASSTGSPEAKGEATALDCCNPEEEMQSTVIDALKSDSITPSE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VR26-1", "uniprot_id": "Q9VR26_DROME", "id": "Q9VR26-1", "name": "", "aln": "---------------MPGR-----KARRKLIKKQQRKRRRQKHAKERDKLEEEAENQRLMQPEYQKWSQEQEEMQEFQRLADERERQLAEESWLRREATAQRQFQMDEAKKRQEQEEVERLQREQAKERAEREERQRKQREEETRKAAKAAAEFDAMMESMDEYLNNPRIEKPPSHLLRVMETHPEERACEFFSRTNCCRYGHACTFNHRRPMLGRILLIRHFFNHSMLQKRCTHKEYASAEEHLELTEQDLRHDYDEFFNDVVEELRKFGTIVNFRTVRNTLEHLRGHVFVEYTNERSALRAFTNLQGRYYASKRLNVEFSNLRTWRGAVCGLSLTRKCPKGNDCGYLHLFGNPNN-LFNTELEYTSGPRSERRSSQTPTAKTP-------SWDEHSEHGRNWR------WSASPEVELENSKDLGNRGRDLKNNQQRNHHSRSRSDRSSVRSKREHSSSGSSHDDRRSKRHHHHHNSTTPDHQHNHCQ--------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: :::: *.: : . . : : : : * : .:.*: ** **.:*: .: :: :: *. :*: : *::.:::::.*.: :: : : ::. :. : *. . . * *: :*..**:*. *: :* * . *::: :* ::: . :.:* .: ** :*:: ::: :*: *.: *::. * :::*:. * ****:*:*:* .*... *: ::**:**.::*: **. : *: *:*** ::**:*:.*.:**:* **:* ::: : .. .. : * : . . . . ...:. :.:.* . . * . . ", "identical_positions": 69, "similar_positions": 152, "identity": "10.75%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1502", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MIX0-1", "uniprot_id": "A0A096MIX0_RAT", "id": "A0A096MIX0-1", "name": "", "aln": "MAVQPPTGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVISDHICLTFTDNGNGMTADKLHKMLSFGFSDKVTVNGHVPVGLYGNGFKSGSMRLGRDAMVFTKNGDTMSVGFLSQTYLEVIKAEHVVVPIVTFNKHRQ-MIYLTESKASLAAMLEHSLFSTEQKLLAELDAIMGK-----KGTRIIIWNLRSYKN-ATEFDFEKDKYDIRIPEDLDEVAGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIIIRGQKVKTQLVSKSLAYIERDVYRPKFLTKTVRITFGFNCRNKDHYGIMMYHKNRLIKAYEKVGCQLKANNMGVGVVGVIECNFLKPTHNKQDFDYTNEY-------RLTILALGEKLNDYWNEMKVKKNSEYPLNLPVEDIQKRPDQTWVQCDACLKWRKLPDGIDQ--LPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKT-------KEKFRIRQPEMLPRILPRINHEIVYQ-TSVSSPSFSPVKESVPRPHISEVASPFAARIINNHLVSAQPEPESNS--------------LKRRLSVRSSILNAKTR----------------------RLSNPPIENSSYK-NDDDED--VIILEENSTPKPAVDLDVRSDIEVKSEQSHAEQTGIEVELVSSPQPGVQASSTSTATSRCDQGTAASTQTEAPGLMVKKEES-----MEEDMDVRN--------------------GRAAL-SCVSAEVKV---------------QETSAESADAAGHQ------LQELRSELLLVTQER---DDYKRKCQVFADQIQVLQRRLLEMN----DQCVKKEMCHQSTEMD------AVFLLG--SVNGQSESPGHVGSQYQQALE---EIERLKKQCSALQHVKGECSQSSCTESKSEMDEMAVQLDDVFRQLDKCTIERDQYRSEVQLLEMEKS---HMHSRCEELKTEVEQLKSTS---QQAGADVSTSSSAEEAVS--YVDGES-------------LKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISSS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F7BJB9-1", "uniprot_id": "MORC3_MOUSE", "id": "F7BJB9-1", "name": "MORC family CW-type zinc finger protein 3", "aln": "MAAQPPTGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVISDHICLTFTDNGNGMTADKLHKMLSFGFSDKVTMNGHVPVGLYGNGFKSGSMRLGKDAMVFTKNGETMSVGFLSQTYLEVIKAEHVVVPIVTFNKHRQ-MINLTESKASLAAILEHSLFSTEQKLLAELNAIMGK-----KGTRIIIWNLRSYKN-ATEFDFEKDKYDIRIPEDLDETAGRKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIIIRGQKVKTQLVSKSLAYIERDVYRPKFLTRTVRITFGFNCRNKDHYGIMMYHKNRLIKAYEKVGCQLKANNMGVGVVGIIECNFLKPTHNKQDFDYTNEY-------RLTILALGEKLNDYWNEMKVKKNAEYPVNLPVEDIQKRPDQTWVQCDACLKWRKLPDGIDQ--LPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTS------KERFRIRQPEILPRILPQINPELLYQ-TSVSSQSFSPVKESVPRPHLSEVTSPFAARIINLNLASPASEPENSS--------------MKRKLGVHSSILNAKTR----------------------RLSNPPVENSSYK-NDDDED--VIILEENSTPKPAVDLEVKSDIEVKSEQSHTEQSGIHVDLVSSPKPCVQASSTSTSTSRSDPGITVSTQTDAPGLTVKKEES-----MEEDMGVRN--------------------GTATL-SCVGTEAKV---------------QETSAESVDATSHQ------LQELRSELLVVTQER---DDYKRQCQMFTDQIQVLQQRLLEMN----DKCVKKEKCHQSTETD------AVFLLD--SVNGQAESLDHLGSQYQQALQ---EIERLKRQCSALQQVKSECSQASCTESKSEVDEMAVQLDDVFRQLDKCTIERDQYKNEVQLLEIEKS---HIHSQCEELQTEVEQLKSTG---QQAAADGSTASNAEEPVS--YVDGES-------------LKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14149-1", "uniprot_id": "MORC3_HUMAN", "id": "Q14149-1", "name": "MORC family CW-type zinc finger protein 3", "aln": "MAAQPPRGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVINDHICLTFTDNGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGLYGNGFKSGSMRLGKDAIVFTKNGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKHRQ-MINLAESKASLAAILEHSLFSTEQKLLAELDAIIGK-----KGTRIIIWNLRSYKN-ATEFDFEKDKYDIRIPEDLDEITGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAYIERDVYRPKFLSKTVRITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGVGVVGIIECNFLKPTHNKQDFDYTNEY-------RLTITALGEKLNDYWNEMKVKKNTEYPLNLPVEDIQKRPDQTWVQCDACLKWRKLPDGMDQ--LPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTN------KEKFRIRQPEMIP----RINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYATRLLNNHQVPPQSEPESNS--------------LKRRLSTRSSILNAKNR----------------------RLSS-QFENSVYKGDDDDED--VIILEENSTPKPAVD----HDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEET-----VEDEIDVRN--------------------DAVILPSCVEAEAKIH------------ETQETTDKSADDAGCQ------LQELRNQLLLVTEEK---ENYKRQCHMFTDQIKVLQQRILEMN----DKYVKKETCHQSTETD------AVFLLE--SINGKSESPDHMVSQYQQALE---EIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKS---QIRSQCEELKTEVEQLKSTN---QQTATDVSTSSNIEESVN--HMDGES-------------LKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U1B0-1", "uniprot_id": "A0AB32U1B0_DANRE", "id": "A0AB32U1B0-1", "name": "", "aln": "MAAQTERGILLSALNPKFLHTNSTSHTWPFSAIAELIDNAYDPDVSAKQFWIDKTAIRGEDCLIFMDNGSGMDNDKMFKMLSFGFSDKETINGHVPVGLYGNGFKSGSMRLGRDAIVFSKNKESMCVGLLSQTYLEAIQAENVIVPIVSFKRVGQSMLPEAQHAASLHDILQYSLFRTEAELLCELKAINAHYANECTGTRIIVWNLRKTSSGKSEFDFDIDRYDIQIPAEVYENEKEK-YKQPCRTFQSSPESDFSLRAYCSILYLKPKMQIILRGQKVKTQLISKSLAHIVKDKYKPNFLNERIPITFGYNTKSKEHYGVMMYHKNRLIKAYERVGCQNRANEKGVGVIAVIECNFLKPTHNKQDFDYTEEYREGYKQYRRTITTLGVKLEEYWKAIRHKKG--FDNNLPMEDIPKRPDQNWVQCDECLKWRKLPDGIDMNKLPDKWFCRMNPDPQFRRCEENEEAEDSADEASTCLKTYKEYERNLKRQQEQKKIKAEETRLRQEQQKNAELIKQNESLKRMHSSLVRQLHHNPPSSPRSPTVSWQAMSPHNSQTASSPSDNMPVISNVCSLSTPKRVKRPLSLSQSQTAKRARPHDDYSVNTPGSPSISAAALDVRTSPGNANNNVNISDDSSEDDDIVIDEVHSTPRPKPS---TFDLSKVKTEENNSDNAIELFMECSDQALVDTETEDTTKGPSTSEGQTNTTTQTECLSIKKEEDQQMQKKETEIKEENKNDPRAIKQSPGEVEGGIIKESMEVNTCSSSEVSRTNLDGIPKENSLSLEQQTKSDVLNQGSRQSPSTSLFPNIEIDLLPTSEAQKQQDNLLEILEATAQERDKFKEKVLEKEIQLLKLSIKKDHSHQCIQTDPSEDYKTLYLQANQSIQKLTEERDELKRKEEALLKGKAEKEAQDEVCRERLKAESEGHSSTANAFVDADDEMALQVDFLLSELDTRNAECQELKCKLESLEQEKASYKQLEKEVEELRKQKEQWSKANGDKNTSATQTCSASTAAVLVNGIKNDGESTERPAEGQNTGTPAKLRELRSNVARLLVTFVPALDLDQVNYDCEVIDEILNQVIQEISPSETSFT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.*. ** **** *****************:************.***:*****.* .. ** * ***.** **:.********** *:*********************:**:**:** ::*.**:*******.*:**:*:****:*:: * *: :: *** :*::*** ** :**.**.** .: .*****:****. .. :****: *:***:** :: * .* **: * * :****:*************:****:*********:*****:* :* *:*:**.. : ****:* :.*:***:****:********:**** :**: ****:.:******************:** * ** :** **::**: :: **. : ***:*** *****.***** **********:* **:**:* *******.** **.**. .* ****: :*: :*: * : * *:: : ::. * :: . * : . : : :. : . ..*... :** *. .* : * * * :*. :*..** ::* * :***:* . *:. . :.: .: .:.: : . :. :: : .*:.. . . * *:. * :**** * :: .* : :* :*.. *:*. . : . * : ::. :** .:: : :: . . ::: . ::.::** : . :**: .**. : * :::* *:: :*. ..: : : *: * * .. * :.:.* ..: . . ****:*:* :: :**. . * :: : ::: ** **: ::... ***:.: ** ..:. : :.:: .::*. *. **** ***.** **.:**. :** ***:***** :*:****.**::::* .:: ", "identical_positions": 418, "similar_positions": 280, "identity": "38.28%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1505", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BIQ8-1", "uniprot_id": "ZN770_MOUSE", "id": "Q8BIQ8-1", "name": "Zinc finger protein 770", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------MPLRNVMAENNFKMLKIQQC-VANKLPRNRPYICNICFKHFETPSKLARHYLIHTGQKPFECDVCHKNFRQLVHLERHQLT-------------------------------------------------------------------------HNLPFSCNICQRHFKNLKTFVKHQQLHNESYHNDVK-VRRLLETKQEKPVYGMCN----------------TFTADERWALHPCS--------------------------KSDATYSTTKRRKNIHACTICGKMFPSQSKLDRHSLIHTGQRPFKCVLCSKSFRQSTHLKIHQLTHSEER---------------------------PFQCCFCQKGFKIQSKLLKHKQIHTRNKTLQNLPLKVKSPESCPLPNKLNAKQ--------------------DAFESGDMGESEENN--PLDVHSIY---------------IVPFQCSECEECFESEQILNGHKCLPARGG---------------------RVPSRLKRSCNYKTIVKKLLAKLKRAGGKKSDDLQSEKKRTFKSN---------YLKNCERSSGKPNIEQTQRTFVGSLSRHGSYKTVSKKKKKTLALPFSWQKQFQSQNTGKSLQGILTTGSILSMDGSVNNKDLSIYGS-SGEEYLN-CDMLQCGFSDSSENIHTGHKMCPCDKCDKVFPSISKLQRHYLIHTGQRPFDCNVCGKSFRQSAHLKRHKLTHI--EKIPYSSFWRVDFGN----------------------VNQLFIHPSDDVSYNASQQCEGLG----------------------SQSCESSESSQVSEIEVKVEPEDFLLG----------SHCRSRQSYLANALVESEQSHH--------------------------CYSYLGRPERSDG--------------------------------------------------------LLYQCSVCCKHFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERPQEKVVLDSTV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IQ21-1", "uniprot_id": "ZN770_HUMAN", "id": "Q6IQ21-1", "name": "Zinc finger protein 770", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MMAENNLKMLKIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLT-------------------------------------------------------------------------HSLPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYN----------------TFTTEERWALHPCS--------------------------KSDPMYS-MKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEER---------------------------PFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQ--------------------GGFENGEIGESEENN--PLDVHSIY---------------IVPFQCPKCEKCFESEQILNEHSCFAARSG---------------------KIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKK-VFKKS---------FLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQ------NMGKNLKGILTTENILSIDNSVNKKDLSICGS-SGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHN--EKSPYASLCQVEFGN----------------------FNNLSNHSGNNVNYNASQQCQAPG----------------------VQKYEVSESDQMSG--VKAESQDFIPG----------STG---QPCLPNVLLESEQSNP--------------------------FCSYSEHQEKNDV--------------------------------------------------------FLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERPQGKVVALDSVM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QH90-1", "uniprot_id": "E9QH90_DANRE", "id": "E9QH90-1", "name": "", "aln": "MDVSLPNKNVADWDTEQSSACVSKSSEDVWMGKKQEFEKEQEPVMAKHSMDKDASSEVLSNVSDNRSEKKKVHECPLCLKRFGVLYKLKRHCLIHTNERPFQCPICVHSFRERSHLKVHLRTHTNPVMQSTIQKHGFSSVPCNQASTAQSDANSTDEHKSVEVDLTKTYSDVETIGSESGLKIIKGPRCPLCLKCFQSPSKLKRHIMIHTEQKPFKCYVCSKTFHLRSHLKIHKCKGKIRPECNTFLGNGLVEENRVEGEDLGTRMAPVSKSSDVRPLLLTKKNRYQCEICLKVFSVFSNLKRHRFVHLASKPYTCTICWKSFKQARYLHKHLKQHKEKRHFPSRMCDVKKKNEGNSSTPGAFDGSNNSRLNAGDVSQNLSTVDKQHLEMLQCDNHLNQNAPLINSSADTLKEEVIEEQIADANPTYFKHTSKNVNQCKICLKKFSYPSRLSRHLLVHTDDKPFKCSECSKSFRNPYHLRRHQKIHKREKKYIANKTGHQLLYSSNVTSTSLLKTDSGYQCDVCLKTFSVPSKLRRHQIVHSGTKPYTCMICRKSFSQAYSLTKHIKLHTGKVNSPSLLHWLRGSKSSITGALQTNNCGPNDANASLPKELDSVDGQTNEKLQDHSQLDQNVSLTESSNTVKTESEDVLKDSEEPTANSSPTNSLDKSNDENQCVICLKTFPYPSKLSRHLLTHTDFKPFQCTVCSKSFRNESNLQSHEKFHKKTGKKRISAYSGPVYQCEICLKKFNFPSRLKRHLSIHSGAKPYSCMICGKSFRLPEYLSEHLKIHKGKKRNHSSRLHGVPQKQGMDDKGSDTQTDENQSQNLSDVSSDTETQTPGNSSPMYPESRSGGVNQCVICLKIFPNHPLLFKHLLGHADFTPLKCNVCLKSFRYLCNLESHKKMHHKAAKEKIAGNSQQDCADSGKAVASKDQDLKMPSSQDGATVHQDPNMLADNASQKMSGNCSDSGGLTSNGTRFLGNVVPNSEVITQSSKKTVLGLTHNTDISVPAEKKAFDIVPFGRVSDFPPKTDSSLQPCASNSRTEQTWAHHTGNIKEEVSFVDSDTIKHVPESSVPPVSLHTQKPDNSNLSNADVRGQLNFQDPSGHCNKPQHDFLICSDCGQSFPTEQKFYAHKCTNLESTEKFKKFHQCDICFKVFNVPSKLKRHIISHTGQKPYKCPHCQKGFTQSHNMKAHMLTHTFEDIPQGLSS-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: . . .:: . * : * :*:* *::**** ** :*** ****:* ** *.*: **: *: . . *:.*.** : **: : : ** : *:*. : : : : :.. * : : . .:: : *. . : **:: *.** * *. *:*.** *:**.::**** *:****:. **: ** *..*: :** .* * *.: *** :*: :*: .*. : : .:: .*.:::: : ..::..: * .: * * ::.*: *.: .. ***::*: . .*... **::.* :* .* : ..: :: .::**.:* *.. : :*: : . . : .:. . .*. : *. *. :* : : : . : . . .:*.. ...: . * . .: . : * * . : * * *:**. . * :* * *:. *: **:* **** .:*: *: * * :. : : .: .:: .::.. : * :*. * .. : : * .* : * . *. .* *. :: : : :..: :::*.:* * *. ****:** : *:****::*. * * * *: : * * *** * : ", "identical_positions": 163, "similar_positions": 233, "identity": "13.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1515", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96S65-1", "uniprot_id": "CSRN1_HUMAN", "id": "Q96S65-1", "name": "Cysteine/serine-rich nuclear protein 1", "aln": "MTGLLKRKFDQLDEDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGPWDQ--MPLPDRDFCGPRSFTPLSILKRARRERPGRVAFDGITVFYFPRCQGFTSVPSRGGCTLGMALRHSACRRFSLAEFAQEQARARHEKLRQRLKEEKLEMLQWKLSAAGVPQAEAGLPPVVDAIDDASVEEDLAVAVAGGRLEEVSFLQPYPARRRRALLRASGVRRIDREEKRELQALRQSREDCGCHCDRICDPETCSCSLAGIKCQMDHTAFPCGCCREGCENPMGRVEFNQARVQTHFIHTLTRLQLEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMNN-----ELGDNSCSSDMTDSSTASSSASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSDSDFGGEEEEEEEGSVGNLDNLS-CFHPADIFGTSDPGGLASWTHSYSGCSFTSGVLDENANLDASCFLNGGLEGSREGSLPGTSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPHYTSQKVSDSLDN-IEAPHFPLPGLSPPGDASSCFLESLMGFSEPAAEALDPFIDSQ-FEDTVPASLMEPVPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P59054-1", "uniprot_id": "CSRN1_MOUSE", "id": "P59054-1", "name": "Cysteine/serine-rich nuclear protein 1", "aln": "MTGLLKRKFDQLEEDDSSSSSSSSFSSRLSLSSFPASSASPAWNSDEEGPGGQ--APQSDQDSCGLQSFTPPSILKRAPRERPGHVAFNGITVYYFPRCQGFTSVPSRGGCTLGMASRHSTCRLFSLAEFTQEQVRARREKLRRRLKEEKLEMLRWKFSVAGVPESGAGVPLTADAIDDASVEEDLAVAVANGRLEEANFLQPHPPRQRRALLRASGVRRIDREEKRELQVLRQSREDCGCHCDGVCDPETCSCSLAGIKCQMDHTSFPCGCCREGCENPNGRVEFNQTRVQTHFIHTLTRLQMEQGAESLGDLESPVEDTP---VEQAALSPFPPSKPPVSS-----ELGDSSCSSDMTDSSTTLS--SGSSEPPNHPAHPSLPGPSFRSGVDEDSLEQILNFSDSDLGIEEEEEEGGGVGNLDNLS-CFHLADIFGTGDPGSLASWTHSQSGSSLASGILDENANLDASCFLNSGLGGLREGSLPGSSGSPEGDAVQSSSWDLSLSSCDSFELLQALPDYSLGPHYTSRRVSGSPDS-LET-FHPLPSFSPPRDASTCFLESLVGLSEPVTEVLAPLLESQ-FEDAALAPLLEPVPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9QH67-1", "uniprot_id": "E9QH67_DANRE", "id": "E9QH67-1", "name": "", "aln": "MSGVLKRKYEEVAEDPCYSSSSPSS---------LSSSAYSEWDSDGESCYSDTLDSTPSNPSSPATSLNTTSILKKAKRTRRGNVQFDQVTVFFFPRCQGFTSVPSRGGCTLGMMQRHSAQRRYTLAEFAIAQRHLRREKLKNRMREEKLEALKLKLTKNGTQESEEAEKLTVDDIPED------EIDLSGVNVDDGSFLHPYPSKKRYAILKAAGVKKIDREEKRQLHELRTSREDCGCDCQGFCEPETCSCSLAGIKCQMDHSSFPCGCTKDGCGNTQGRIEFNSSRVHTHYIHTIMKLELEKRLEEHTTETPPETHPDSSSLNQPAEISSTPDMPTFHFNSELLSTGENSCSSDMTDSS------SSSGQSEDSESVENVPSEQSPLDVDENGLTRILSFSDTDNEDCSIRERNDNCDYQQKKSEGSMGYGIFSTED--DKLNMSQTDNSRTAMSELLDENANQGNGLFHSS--------FIPHTP-SPSIDHS-ASYMDLSLSSESDLEFFDGFPCLGPSSLYNSLKEYEHVDNFFQFQLPTYPSLPQAVDPGTCLLESLIGLSDSVPEPPTTFTDNQMLEDAMKLSVMESLKV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*:****:::: ** . ***.* :**. *:*: *. .: . ... . *:.. ****:* * * *.* *: :**::******************** ***: * ::****: * : *:***:.*::***** *: *:: *. :: . ..* * : : ::. .::: .**:*:*.::* *:*:*:**::*******:*: ** *******.*: .*:*****************::***** ::** *. **:***.:**:**:***: :*::*: *. .* . ::. . . *.. . *:.********** *.:.:. : : .:*. .**::.* :**.***:* . .*. .. . :: * .**.* * . . ::: .. : * :****** . . * .. :* :. .*. * :* ****** ..:*:::.:* . .. *.* : *. :: . *.:. . *..:*:****:*:*:...* .: :.* :**: .::*.: *", "identical_positions": 211, "similar_positions": 190, "identity": "35.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1516", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZUN1-1", "uniprot_id": "A0A8I5ZUN1_RAT", "id": "A0A8I5ZUN1-1", "name": "Flavin reductase (NADPH)", "aln": "--MAVKKIAIFGATGRTG-----LTTLAQAVQAGYEVTVLVRDSSRLPSEGPQPAHVVVGDVLQAGDVDKTVAGQDAVIVLLGTGNDLSP--TTVMSEGTRNIVAAMKAHGVDKVVACTSAFLL-WDPSKVPPRLQDVTDDHIRMHKILEESGLKYVAVMPPHIG---DQPLTGAYTVTLDGRGPSRVISKHDLGHFMLRCLTTHEYDGQKTYPSHQAGGRTQGLALPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q923D2-1", "uniprot_id": "BLVRB_MOUSE", "id": "Q923D2-1", "name": "Flavin reductase (NADPH)", "aln": "--MTVKKIAIFGATGRTG-----LTTLAQAVQAGYEVTVLVRDSSRLPSEGPQPAHVVVGDVRQAADVDKTVAGQEAVIVLLGTGNDLSP--TTVMSEGTRNIVTAMKAHGVDKVVACTSAFLL-WDPTKVPPRLQDVTDDHIRMHKILQESGLKYVAVMPPHIG---DQPLTGAYTVTLDGRGPSRVISKHDLGHFMLRCLTTNEYDGHTTYPSHQYD----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30043-1", "uniprot_id": "BLVRB_HUMAN", "id": "P30043-1", "name": "Flavin reductase (NADPH)", "aln": "--MAVKKIAIFGATGQTG-----LTTLAQAVQAGYEVTVLVRDSSRLPSEGPRPAHVVVGDVLQAADVDKTVAGQDAVIVLLGTRNDLSP--TTVMSEGARNIVAAMKAHGVDKVVACTSAFLL-WDPTKVPPRLQAVTDDHIRMHKVLRESGLKYVAVMPPHIG---DQPLTGAYTVTLDGRGPSRVISKHDLGHFMLRCLTTDEYDGHSTYPSHQYQ----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N0W6-1", "uniprot_id": "A0A8M1N0W6_DANRE", "id": "A0A8M1N0W6-1", "name": "", "aln": "MSDAVRNVAIFGCTGMTG-----LATLPIAVASGYNVTVLVRDPARLPPD-HKASRVVVGDVLNKNDVKKTLEGQDAVIIILGTRNDLSP--TTMMSEGTRNIVEVMKARGIRKVVGCMSAFLL-WDRSKVPPRLVPVTEDHDRMYTVLKESGLDYIAAMPPHIAG--DKPLTEKYIVTEN-MLKGRVISKYDLGHFFVKCLSTSEWDGKTVGICGEYS----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VH72-1", "uniprot_id": "Q9VH72_DROME", "id": "Q9VH72-1", "name": "NAD(P)-binding domain-containing protein", "aln": "----MQRIAIIGGTGMTG-----ECAVDHALQKGLSVKLLYRSEKTVPERFKSKVELVKGDVTNYEDVQRVIEGVDAVAVILGTRNKLEA--TTELSRGTENLIKAMKEAKLTKFSIVMSSFLL-RPLNEVPTVFHRLNEEHQRMLDLTKACDLDWIAILPPHIA---DEPAT-AYTVLHD-EAPGRLVSKYDLGKFIIDSLEQPEHYRKVCGIGKSPKSA--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04304-1", "uniprot_id": "YMY0_YEAST", "id": "Q04304-1", "name": "UPF0659 protein YMR090W", "aln": "--MSPMKVAVVGASGKVGRLLINQLKANDSFSTPLAIVRTQDQVNYFKNEVGVDASLTDIENASVSEITDAIKAYDAVVFSAGAGGKGMERIFTVDLDGCIKVVEACEKAGIKRFVVVSALKAEDRDFWYNIKGLREYYIAKRSADREVRNSNLDYTILQPGSLELNKGTGLLQPLDKLEEKASVNYSINREDVASFIVESLLHPNATVKKTISLVNGNEPMEKFIQSL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:*:.* :* .* :. : . . :. : . :: .: . :** . *: .. * * ::: . : : :. : : : . ..*.: * : . : . :.: *:. *:: .* : : . ", "identical_positions": 14, "similar_positions": 56, "identity": "6.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1518", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUJ3-1", "uniprot_id": "MYOME_RAT", "id": "Q9WUJ3-1", "name": "Myomegalin", "aln": "--------------------------------------------------------------MSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEVSRE--------------DVYKRNIELKVEVESLKRELQDRKQHLHKTWADEE-------------------------------------------------------DLNSQNEAELRRQVEEPQQETEHVYELLDNNIQLLQEESRFAKDEATQMETLVEAEKGCNLEL----SERWKDATKNREDAPGDQV---------KLDQYSAALAQRDRRIEELRQSLAAQEG------LVEQLSREKQQLLHLLEEPGGMEVQP----------------------MPKGLPTQQKPDLNETP------TTQPSVSDSHLAELQDKIQQTEVTNKILQEKLNDMSCELRSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLPEMLHQSQLGQLQSSEGIAPAQQQVALLDLQSALFCSQLEIQKLQRLLRQKERQLADGKRCMQFVEAAAQEREQQKEAAWKHNQELRKALQHLQGELHSKSQQLHVLEAEKYNEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDTTDKTLDTNEVFLEKLRQRIQDRAVALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEVEQLIATCQNLQWLKEELETKFGHWQKEQESIIQQLQTSLHDRNKEVEDLSATLLHKLGPGQSEVAEELCQRLQRKERVLQDLLSDRNKQAMEHEMEVQGLLQSMGTREQERQAVAEKMVQAFMERNSELQALRQYLGGKELMAASQAFISNQPAGATSVGPHHGEQTDQGSTQMPSRDDSTSLTAREEASIPRSTLGDSDTVAGLEKELSNAKEELELMAKKERESQIELSALQSMMAVQEEELQVQAADLESLTRNIQIKEDLIKDLQMQLVDPEDMPAMERLTQEVLLLREKVASVEPQGQEGSENRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAQPETFERDRTLQVELEGAQVLRSRLEEVLGRSLERLSRLETLAAIGGATAGDETEDTSTQFTDSIEEEAAHNSHQQLIKVSLEKSLTTMETQNTCLQPPSPVGEDGNRHLQEEMLHLRAEIHQPLEEKRKAEAELKELKAQIEEAGFSSVSHIR-NTMLSLCLENAELKEQMGEAMSDGWEVEEDKEKGEVMVETVVAKGGLSEDSLQAEFRKVQGRLKSAYNIINLLKEQLVLRSSEGNTKEMPEFLVRLAREVDRMNMGLP-SSEKHQHQEQEN-MTARPGPRPQSLKLGTALSVDGYQLENKSQAQDSGHQPEFSLPGSTKHLRSQLAQCRQRYQDLQEKLLISEATVFAQANQLEKYRAILS-ESLVKQDSKQIQVDLQDLGYETCGRSENEAEREETTSPECEEHGNLKPVVLVEGLCSEQGYLDPVLVSSPVKNPWRTSQEARG-VQAQGTSDDSSLLRKDIRDLKAQLQNAYKVIQNLRSRVRSLSATSDYSSSLERPRKLRAVATLEGASPHSVTDEDEGLLSDGTGAFYPPGLQAKKNLENLIQRVSQLEAQLPKTGLEGKLAEELKSASWPGKYDSLIQDQARKTVISASENTKREKDLFSSHPTFERYVKSFEDLLRNNDLTTYLGQSFREQLSSRRSVTDRLTSKFSTKDHKSE-KEEAGLEPLALRLSRELQEKEKVIEVLQAKLDTR---FSSPPSSHAASDSHRSASSTSFLS-------DDIEACSDMDVASEYTHYEEKKPSPSN-----------------SAASASQGLKGEPRSSSISLPTPQNPPKE--ASQAQPGFHFNSIPKPASLSQAPMHFTVPSFMPFGPSGPPLLGCCETP-VVSLAEAQQELQMLQKQLGRSVS---IAPPTSTSTLLSNHTEASSPRYSNPAQPHSPARGTIELGRILEPG--YLGS-GQWDMMR---PQKGSISGELSSGSSMYQLNSKPTGADLLEEHLGEIRNLRQRLEESICVNDRLREQLQHRLSSTARENG--STSHFYSQGLESMPQLYNENRALREENQSLQTRLSHASRGHSQEVDHLREALLSSSSQLQELEKELEQQKAERRQLLEDLQEKQDEIVHFREERLSLQENNSRLQHKLALLQQQCEEKQQLSLSLQSELQIYESLYENPKKGLKAFSLDSCYQVPG--ELSCLVAEIRALRVQLEQSIQVNNRLRLQLEQQMDHGAGKASLSSCPVNQSFSAKAELANQQPPFQGSAASPPVRDVGLNSPPVVLPSNSCSVPGSDSAIISRTNN--GSDESAATKTPPKMEVDAADGPFASGHGRHVIGHVDDYDALQQQIGEGKLLIQKILSLTRPARSVPALDAQGTEAPGTKSVHELRSSARALNHSLEESASLLTMFWRAALPNSHGSVLVGEEGNLMEKELLDLRAQVSQQQQLLQSTAVRLKTANQRKKSMEQFIVSHLTRTHDVLKKARTNLEMKSFRALMCTPAL--------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80YT7-1", "uniprot_id": "MYOME_MOUSE", "id": "Q80YT7-1", "name": "Myomegalin", "aln": "--------------------------------------------------------------MSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEVSRE--------------DVYKRNIELKVEVESLKRELQDRKQHLDKTWADAE-------------------------------------------------------DLNSQNEAELRRQVEERQQETEHVYELLGNKIQLLQEEPRLAKNEATEMETLVEAEKRCNLEL----SERWTNAAKNREDAAGDQE---------KPDQYSEALAQRDRRIEELRQSLAAQEG------LVEQLSQEKRQLLHLLEEPASMEVQP----------------------VPKGLPTQQKPDLHETP------TTQPPVSESHLAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGIAPAQQQVALLDLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQELRKALQHLQGELHSKSQQLHVLEAEKYNEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKTLDTNEVFLEKLRQRIQDRAVALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEVEQLTATCQNLQWLKEELETKFGHWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEVAEELCQRLQRKERMLQDLLSDRNKQAVEHEMEIQGLLQSMGTREQERQAAAEKMVQAFMERNSELQALRQYLGGKELMTSSQTFISNQPAGVTSIGPHHGEQTDQGSMQMPSRDDSTSLTAREEASIPRSTLGDSDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAMQEEELQVQAADLESLTRNVQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVEPQGQEVSGNKRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAQPENSERDGTLQVELEGAQVLRTRLEEVLGRSLERLSRLESLAAIGGG------------------------------------ELESVQAQ--------------------EMLHLRAEIHQHLEEKRKAEVELKELKAQIEEAGFSSVSHISRNTMLSLCLENAELKEQMGEAMSDGWEVEEDKEKGEVMLETVVAKGCLNENSLQAEFRKVQGKLKSAYNIINLLKEQLLLRSSEGNSKEMPELLVRLAREVDRMNTGLP-SLGKHQHQEQENTTTARPGSRPQSLPLGAALSVDGYQLENKSQAQDSGHQPEFSLPGSTKHLRSQLAQCRQRYQDLQEKLLISEATVFAQANQLEKYRAVFS-ESLVKQDSKQIQVDLQDLGYETCGRSENEAEREETTSPECEEHNNLRPVVLMEGLCSEQGYLDPVLVSPPAKKPLENKPGKQEEFRAHGTPDDSSLLRKDIRDLKAQLQNANKVIQNLRSRVRSLSATSDYSSSLERPRKLRAVATLEGASPHSVTDEDEGWLSDGTGAFYPPGLQAKKDLESLIQRVSQLEAQLPKTGLEGKLAEELRCASWPGKYDSLIQDQARELSYLRQKIREGRGICYLLTQHAKDTVKSFEDLLRSNDIDYYLGQSFREQLAQGGQLTERLTSKLSTKDHKSE-KEEAGLEPLALRLSRELQEKEKVIEVLQAKLDTR---SLSPPSSHAVSDSHRSASTTSFLS-------DDIEACSDMDVASEYTHYDEKKPSPSH-----------------SAASASQGLKGESSSSPISLPTPQNPPKE--ASQAHPGFHFHSIPKPASLSQTPMHSALPSFVPFSPSGPPLLGCCETP-MVSLAEAQQELQMLQKQLGESVS---IAPPASTSTLLSNQTEASSPHYINPAQPHTPTRSTIELGRILEPG--YLGSSGQWDMMR---PQKGSVSGELSSGSSMYQLNSKPTGADLLEEHLGEIRNLRQRLEESICVNDRLREQLQHRLSSTARENG--STSHFYSQGLESMPQLYNENRALREENQSLQTRLSHASRGHSQEVDHLREALLSSRSQLQELEKELEQQKAERQ-----------------------------------------------QLSLQSELQIYESLCENPKKALKAFSLDSCHQVPG--ELSCLVAEIRALRGQLEQSIEVNNRLRLQLEQQMDRGAGKASLGPIAVGQSFPDKAEPAN---LHQGSAASPPVRDVGLNSPAMVLPNSSCSAPGSDHAIVTRTNNELSSDDSAAMKNPPKLEVDATDGPFANKHGRHVIGHVDDYDALQQQIGEGKLLIQKILSLMRSARSIPGQEAQDTEAPGNISAHELRSSAKALNHALEESTSLLNMFWRAALPNTHGPVLVGKEGQLMEKELLDLRAQVSQQEQILQNTAARLKRANQRKKSMEQFIVSHLTRTHDVLKKARTNLEMKSFRALTCTPAL--------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VU43-1", "uniprot_id": "MYOME_HUMAN", "id": "Q5VU43-1", "name": "Myomegalin", "aln": "--------------------------------------------------------------MSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASRE--------------DIYKRNIELKVEVESLKRELQDKKQHLDKTWADVE-------------------------------------------------------NLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLEL----SEKLKGVTKNWEDVPGDQV---------KPDQYTEALAQRDKRIEELNQSLAAQER------LVEQLSREKQQLLHLLEEPTSMEVQP----------------------MTEELLKQQKLNSHETT------ITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQALMERNSELQALRQYLGGRDSLMS-QAPISNQQAEVTPTG-RLGKQTDQGSMQIPSRDDSTSLTAKEDVSIPRSTLGDLDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAVQEEELQVQAADMESLTRNIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQGQEISGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERDRTLQVELEGAQVLRSRLEEVLGRSLERLNRLETLAAIGGAAAGDDTEDTSTEFTDSIEEEAAHHSHQQLVKVALEKSLATVETQNPSFSPPSPMGGDSNRCLQEEMLHLRAEFHQHLEEKRKAEEELKELKAQIEEAGFSSVSHIR-NTMLSLCLENAELKEQMGEAMSDGWEIEEDKEKGEVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHNIINLLKEQLVLSSKEGNSKLTPELLVHLTSTIERINTELVGSPGKHQHQEEGN-VTVRPFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQDLGYETCGRSENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQEEFRVYGKSENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPRKLRAVGTLEGSSPHSVPDEDEGWLSDGTGAFYSPGLQAKKDLESLIQRVSQLEAQLPKNGLEEKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLITRHAKDTVKSFEDLLRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKSE-KDQAGLEPLALRLSRELQEKEKVIEVLQAKLDAR---SLTPSSSHALSDSHRSPSSTSFLS-------DELEACSDMDIVSEYTHYEEKKASPSHSDSIHHSSHSAVLSSKPSSTSASQGAKAESNSNPISLPTPQNTPKE--ANQAHSGFHFHSIPKLASLPQAPLPSAPSSFLPFSPTGPLLLGCCETP-VVSLAEAQQELQMLQKQLGESAS---TVPPASTATLLSNDLEADSSYYLNSAQPHSPPRGTIELGRILEPG--YLGSSGKWDVMR---PQKGSVSGDLSSGSSVYQLNSKPTGADLLEEHLGEIRNLRQRLEESICINDRLREQLEHRLTSTARGRG--STSNFYSQGLESIPQLCNENRVLREDNRRLQAQLSHVSREHSQETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHFREERLSLQENDSRLQHKLVLLQQQCEEKQQLFESLQSELQIYEALYGNSKKGLKAYSLDACHQIPLSSDLSHLVAEVRALRGQLEQSIQGNNCLRLQLQQQLESGAGKASLSPSSINQNFPASTDPGNKQLLLQDSAVSPPVRDVGMNSPALVFPSSASSTPGSETPIINRANG-LGLDTSPVMKTPPKLEGDATDGSFANKHGRHVIGHIDDYSALRQQIAEGKLLVKKIVSLVRSACSFPGLEAQGTEVLGSKGIHELRSSTSALHHALEESASLLTMFWRAALPSTHIPVLPGKVGESTERELLELRTKVSKQERLLQSTTEHLKNANQQKESMEQFIVSQLTRTHDVLKKARTNLEVKSLRALPCTPAL--------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B7P4-1", "uniprot_id": "A0A8M2B7P4_DANRE", "id": "A0A8M2B7P4-1", "name": "", "aln": "MMLDSKSKDVCRICARELYGNQRRWIFHPTAKLSLQVLLSYALGREMTRDGRGEFACSKCAFMLDRMYRFDTVIARVEALSLERMQKLLLEKDRLRQCISGLYRKNNTDELGVDGGATDATVVDFARLAEAEYSALLQEDLTYSVYESWAEQCPQEQIQDHQCPLHHADAASGPRPRKCKGCAALRVTDSDYEAVCKVPRKVGRSTSCGPSTRYSGSVQDNTEETVPSAPPPEPIENNQSCELKPVGVSPASSVESLDTAVDVTQESYLKLPLLESEEEQSVVRRPESKPGSVCGLDVALSLLKSCEYHPLQSQRGSRIPVLLKTNTTPMESPYPLLQVPHIEMECPLFPQLPDVPSSIQQELQLELAEMEDQWLDDYVQCKPSGLPKRLIEEQQCHLAEYENAAGQCVNELQKAQQQVQSLQTKIRDSEASNKKLQQKLRDMENELRSVREAACGQETTIQTLGDSLSTKDYEITDLQRVIEEQKELLCSLKQQNNHYQLQQQQVS-GVTPSHLQADLLDLQGSLFSAQLELQGLQRTQQQSQRREDDLTRANQRLQTDLQGAVQRHREAEKHNQDLLTALESARAKLLQTEEKWRDEGRQRENEVEEREKTIRELKTSLEHKERLVQDYSELVDGQKEPAGNRDN---LIQKLKQRIQERDRALERAVDEKFTCMEQKEDEMRKLQLLLREKERDLEKLRCVLSNNEETIMSLEMLLRGKGLELEQVCEAWRSAQGVHSEREESYMRSLRERDALISQLQTSLHTRTKEAEEMTAVLLSKVSVGAGEVAEELKSRLQLKERLFQELLSDRSRQTQEHHSQVQDLLNTISSREHYIKDSAGRVGQVMAEQTARLQELRKQLG-------------------------------------------------------------SANPELTQEDTQALMDELQMTLRREREAQTQLSILRATLASYQDQLQTQTSDLDALSRTASVKEEIIKDLQMQLVEPSDLPLVERLTQELQLLREKVESQEASCNNHKQALLDPLVSMETGQAVQP----------HADFGGFTSDDGEEEEDEEDCNSEFAGSGEDEKRSKRTAQSLVSLQSCDQHQGLRGCQDAVAEG---------------------------------------------------------------PGLAEVKQLVEQKRAVERELMELKSQLEKAGFSSLSQMR-KAFFTLRSQNEELKGLMNLQN-----VGQKSTSCGQLVDTVGAKGKERE-----------------------------------------------------------------------------------------------------------------SAREQTVQLKSDLAQVQQESRELQERLMVSEATVQAQAEQLKDYRELLT-ETSVQQDSKQVQVDIQDLGYETCGRSENEAEREDTSSPEFDDLELCTSLSYRD--AGSQWWAGPATHNSGKPE------------------HDVTYLQQLVEDLRGQLSRSQALIRSLQAQMRDCTPVGTPR---------KVNWGLDNSETQSTAEEDEGWQSSDGFGSLPRQPKQDRELQELVSRVTSLEEQLRKG---KGHADDGKNGNWPGKFDTLIQAQARELSHLRQKMREGRGMCHILTQHLGDTTKTFEELLRSNDIDYYMGQSFRDQLSQSISLAQRVSTKISGRDHSEVPDDKSGHELLAIRLSKELQQKDKLIESLRSKLDQQQPRSDTPTSSHAFSVATDQSDRTSFVSDDHGSTNEDLELCSELDAASEYGQEEAARSATDPRNNRG--------SVLSHPSNPPSITSSHSHKSTNTCPSIHCTPRRPLETQEQTGLTTVPLSNSIPFSASLHCPQMCSQPVFDPHVHPLRTRHPYGGGFSLAEVHQELQMLQRQLGNSYHGPQMKPLPAFPLGPHAQPDHSSLHPLSHHAFEQSPLNSQHTSPAMKSGSSLLESSAMWDMMYSPRPLRPGPYGDVSSGSSGYQSG--HTGTDLMEEHLREIRTLRRRLEDSIQTNDRLRQQLEERLAASARNGAGAAPTNIYIQGLDSVSQLSNEIRVLKEENHTLQNQLQQARTDGSKEMERLREAVLSVRGQLKQAELEADKWADQCRR-----------------------------------MQAQIRDQTQTVLQLKEEKQNSLDNSTRLQQEVNVLQQQLSECQCLVHTLQCELQVYKRVCGTAESNAGSGLTLTLDLRERESNIQLLEQQLRERLDLCMPHPS--ARKQLFHVDQSPSPPVRDTGFSSPASPAIKQHDPKPYKYSGAEG-------------------LEGEAPDGSFACRTGRHMISHVDDFSVLQQQLLEGKAVIRKMEAALQASTESHDLPEG--------YVRNLQVSTKTLKQILEETSSLLRMFWRAALPSTETSAQQLKKEQSLRKEVIALRCKLSEQEQLLRDTMENLRASSQTKDSMEQFIVNQLSRTRDVLKQARSNLEKNELKIASLGFTPLPSSSFSVSSTPSWSERDAVSGVSLKHASSPGWNFVKPHLQDQHKMMTAS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : :. : :: .:. :: : ::*::* . . * :: .*.* :* . : ::**: . .:: ...:: : ** .: : *: *: . ... : : *:. : . *:* **. ...:. *. .*. * :* :**. ** * :: :: * ::. * : :* : * .:: : :.: * :*: . * .: ::.:: .** **:::*.:** **:**.::. **:..:*:: *: ***.* : *.::: * :* :*** *:: :..* : :: ** * : * * :*:: *. *****.:**.:***:* *** :*.:*: * .:. * ::: : :::. : ****:* .**: : :* ...:: : :: **:. : :.*:.*. **.***:*:*: **:: :. . . : :::**:***::: ****.:****:.:*:*:.*:*:*:* :*::::***:** *** ** *: *:* ***.:***:**: : :. * ::.* * .: : :*::::*.******* *.**.*:::*.** *:. * .*:**** .*** ***::*:*****.:*. **. ::*.**:::.:**: : * :: *.: *:.:.** **: ** . ::: . :**:: ::***:* :** *:: :* :::**.*::*:::*:*. .:**::*********:*.*:* :******: ****** * *.. :: . : *: * * . : : :..:.. ... * *.* . :. .* : *:: **: .: : * . .. **.:* :*:** .* ** ***:*:*:*****:*:: :::::* :* *** *. : :.. . :::** :* * * .* :*:*:*:* :*. ::***:*::***** ***::*:.** ::: *: *:*****:***:******************:*:*** :: : : ...* ... .. : .: *:: :.**:.**..: :*:.*::::*. : .. :. *:.:..:*..:**** *.. . . : .::*:.*:.**:.** ** * *:: : ..****:*:*** ***: .: : . . .*:**:***.**: *:*****:**:. .:::*:::*:* :**.. .:::* * **:***:***:*:*:** *::*** : :*.**** * : ... ***:* :::* **::* .*** : : :.:.. .:.... .... ... : *: : .*:. .* :.*: .:.: .:. : * *.* * .****.:*******:***.* * .: . . : .* . . .. .: . . ::.* * * . **:* * : . *::***** ** . **:**:**** ***.**:***:** *****:**:.**:::** . :.:::* ***:*:.** ** *.*:*:*: ** :*.:. *:* : ****:** .:*:: * * :: : : .*:.* * . :: ::. . : . *. : : : *.. . * *:*.:: . . :. :. : .. ..: ******.*:.**. .. . * . :* :*.**.** ***:*.*:**:..*:**: *** :::*: : :.: . ::*: *: :*:: ***::*** ********.:. .. : : .:*:: ** ::*:*:::*:.* .*: :.* *.*******.:*:**:****:**:*** :.:: : ", "identical_positions": 615, "similar_positions": 721, "identity": "23.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1528", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O00411-1", "uniprot_id": "RPOM_HUMAN", "id": "O00411-1", "name": "DNA-directed RNA polymerase, mitochondrial", "aln": "MSALCWGRGAAGLKRALRPCGRPGLPGKEGTAGGVCG------------------PRRSSSASPQEQDQDRRKDWGHVELLEVLQARVRQLQAESVSEVVVNRVDVARLPECGSGDGSLQPPRKVQ------------------MGAKDATPVPCGRWAKILEKDKRTQ---QMRMQRLKAKLQMPFQSGEFKALTRRLQVEPRLLSKQMAGCLEDCTRQAPESPWEEQLARLLQEAPGKLSLDVEQAPS---GQHSQAQLSGQQQRLLAFFKCCLLTDQLPLAHHLLVVHHGQRQKRKLLTLDMYNAVMLGWARQGAFKELVYVLFMVKDAGLTPDLLSYAAALQCMGRQD-QDAGTIERCLEQMSQEGLKLQALFTAVLLSEEDRATVLKAVHKVKPTFSLPPQLPPPVNTSKLLRDVYAKDGRVSYPKLHLPLKTLQCLFEKQLHMELASRVCVVSVEKPTLPSKEVKHARKTLKTLRDQWEKALCRALRETKNRLEREVYEGR-FSLYPFLCLLDEREVVRMLLQVLQALPAQGESFTTLARELSARTFSRHVVQRQRVSGQVQALQNHYRKYLCLLASDAEVPEPCLPRQYWEELGAPEALR-------EQPWPLPVQMELGKLLAEMLVQATQMPCSLDKPHRSSRLVPVLYHVYSFRNVQQIGILKPHPAYVQLLEKAAEPTLTFEAVDVPMLCPPLPWTSPHSGAFLLSPTKLMRTVEGATQHQELLETCPPTALHGALDALTQLGNCAWRVNGRVLDLVLQLFQAKGCPQLGVPAPPSEAPQPPEAHLP-HSAAPARKAELRRELAHCQKVAREMHSLRAEALYRLSLAQHLRDRVFWLPHNMDFRGRTYPCPPHFNHLGSDVARALLEFAQGRPLGPHGLDWLKIHLVNLTGLKKREPLRKRLAFAEEVMDDILDSADQPLTGRKWWMGAEEPWQTLACCMEVANAVRASDPAAYVSHLPVHQDGSCNGLQHYAALGRDSVGAASVNLEPSDVPQDVYSGVAAQVEVFRRQDAQRGMRVAQVLEGFITRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSDFPQEFVWEASHYLVRQVFKSLQEMFSGTRAIQHWLTESARLISHMGSVVEWVTPLGVPVIQPYRLDSKVKQIGGGIQSITYTHNGDISRKPNTRKQKNGFPPNFIHSLDSSHMMLTALHCYRKGLTFVSVHDCYWTHAADVSVMNQVCREQFVRLHSEPILQDLSRFLVKRFCSEP-QKILEAS------QLKETLQAVPKPGAFDLEQVKRSTYFFS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BKF1-1", "uniprot_id": "RPOM_MOUSE", "id": "Q8BKF1-1", "name": "DNA-directed RNA polymerase, mitochondrial", "aln": "MSALRWTRSAAGLGRVLRSPGPHRPPSEEGTFGGFCS------------------SRRSSAASPREQHVLR--EWGHAELLEVLEARVRQLRAEGTPEMRVKKVQVDRPPQGHSS-----------------------------------------RWAQKLEAEKRVK---QRRQKEVDQQKQALTQ--EFWTLHK----EPKIWNKKLAGYLQPSKKGTPTNSEEKQLAQALQAALGRLSSREAEALARKKAKAVEAQILVLQQKFLAFFECCVCTGQVPLAHHVLVTHHNNGDRQQVLTLHMYNTVMLGWARKGSFRELVYVFLMLKDAGLSPDLCSYAAALQCMGRRD-QDVRTIQRCLKQMMEEGFQPQLLFTDLVLEEEDRAALLRAVVKAEPAFRPPPQAPSPVNTSTLLKDIYSKEGPVSYPKLHLPLDTLQDLFYQQLHVELSSSVCVQSVEKAPVMSKEVIEARKTLQALREQWEVELLRVLRETKATMGRQAYEGQ-PTLYPFLCLLSEGEFVSILMQVLKVLPAQGEPLIQLAHNLGLRVLNRHLVKQKQVTNHVQKLGQRYSQYLQLLASDTQV-APCLPREYWESLGPLEAPA-------QQPWSVPVLLQLGKQLAELLVQAVQMPRSLAARQGAQRSIPVLYHVYSFRSYRQVGILKPHPAFTHLLETAAEPTLTFETTEVPMLCPPLPWTSLHSGAYLLSSTKLMRATEGTTQHQRLLEQCPPAQLHGPLDALTQLGNCAWRVNGHLLDLVLQIFRDKGCMPLGVPPPRSEAPRPARYQLP-PGSTPVHKSELRKELARCLKVAREMHSLRSEALYRLSLAQHLRHRVFWLPHNMDFRGRTYPCPPHFNHLGSDLARALLEFAEGRPLGPRGLDWLKIHLINLTGLKKGDSLRMRLAFADEVMEEILDSADNPLTGRKWWMEADEPWQTLACCMEVAHAVRSPDPAAYISHLPVHQDGSCNGLQHYAALGRDSVGAASVNLTPSDLPQDVYREVATQVEEFRQQDAKEGLRVAQVLEGFISRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSDFPQEFVWEASHYLVRQVFKSLQEMFTSTRAIQHWLTESANLISHAGWPVEWVTPLGIPIIQPYHRESKVQVKGG-LQSITLTSSVDESQKPNTLKQKNGFPPNFIHSLDSSHMMLTALHCYRKGLIFVSVHDCFWTHAADIPTMNEVCREQFVRLHSQPILEDLAKFLKKRFCSVSSIKSLKSSERALVTKLQETLQSLPKTGTFDLGQVIRSTYFFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B7G4-1", "uniprot_id": "A0ACD6B7G4_DANRE", "id": "A0ACD6B7G4-1", "name": "DNA-directed RNA polymerase", "aln": "MSLLRLCAYSAALTRSFAADGCLR-SFLKGDCCRMCLRIRINGERQIQDKTWATIYRRHYSVIPKKDDGKKR-VWEQSQLLDVLEARIQQLHSDAIVDVKHSKVQIIKAKQRAKKTSPGKSQKNLPGEKAEMLKSGPSAQKKNVTEGVTPANTHASRWMAKLNREMWINPKTKTSKKVIKTGQSSKTKHCTNNAQNKG--KGFRVSERLLAKFPDLQKIHSGEVSLISVISDKALVNEGELDVS-VPAPEKLLVDKEGNRYEDSHLRVRCYLEACMFLDDVSRAHNYLLSHHRQLSKRSQLSISTYNIVMRMWAKKGSINNIRRLFSLIEEAGMKPNVTSYCAALECMGRMQNCETVVIARCLQQMGADGLSVDDVLSQCVFKKDEREMVLRAVQLVIPHFQPSVSKTQPVCSLPLVKQFYAEREDAIYPKLDYSLKELQDRFNLQLAMEKATTVTINSVEALKPVTENMAHMRELLAKQRKHWEKALLQALKDRKQMMSNNSQKSWNTCLYPYLCILDDQEYVDIMLQSLDKLSPNGESLLFMADEMGNRVYNLYCIRQKSQSQMVEKLRSIYSSYAELLANDTET-NGMLPRECWTNLEISGNRSGPSLLSDDTPWPMILMVQLGSFLVDLMVHELKIQSNILNPALEKKLIPILYHMYTFRSNHKIGFIKPHPILTRILREATETKLTFDSYVMPMLCPPVPWTSPKSGAYLLTPAKLMRASDGAMQHQLLLEKTQEEDLHAVLDSLNQVGSCPWKINKPLLDIIISIFNDKGSDKLSIPPPLSEAPEIPRFNPHDPSYTQVEKAFMKREGIKAKKVVAEMHSLRMDALYKLSIANHVRDKIFWFPHNMDFRGRTYPLPPYFNHLGSDVTRALLLFAEGRPLGPKGLDWLKIHLVNLTGLKKQSSLDGRLEYAESIMEDILDSADHPLDGRKWWMNADEPWQALACCMEIANASRSPDHHKFISYFPVHQDGSCNGLQHYAALGRDVIGATSVNLMPCALPQDVYSGVAKQVEEFRVRDAERGLKIAQVLQGFISRKVVKQTVMTVVYGVTRYGGRLQIEKRLKEIDDFPKDYVWDASHYLVVQVFNSLKEMFTGTREIQEWLTESARLIAKSGRTVEWVTPLGLPIIQPYHR-IRNQILKGNIQNLNIHISHDANEKPDSMKQKNAFPPNFIHSLDSTHMMLTSLHCHRAGLTFVSVHDCYWTHAVTVDIMNRVCREQFVALHSQPILEELSWFLLQKYSRRPPVGSKPKK-LLEYYTLMKVLSSVPQTGDFDLEKVKDSVYFFS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * :*.* * : . * . :* .* ** :. *:::. : * : :**:**:**::**:::. :: .:*:: : : . ** *: : : : : :. . : : : :: .: :* : . : . . :: *.*. * . : : :. .:::.*: .::. **: *: ** : .::. *:: ** ** **::*::.:: :: ::::**:.*:: **.***:**** : :. .* ***:** :*:. : ::: ::.:::* :*:** . * * . . . ** : *:::.*:: . ****. .*. ** * ** :* :: * : *** :::: . *: * *.:** * :.*:: * : .: :. ***:**:*.: * * :::* *. *..:**.: :* ::. *. . : :::: : *: * . * .* ***.*::. ***: * .* : **.: : ::**. *.:::*: :: .: .: :*:***:*:**. :::*::**** .::*. *:*..***:: :******:**** :***:**:.:****: :*: *** *** **. **:*.*:*.*.*::* :**:::.:*. **. *.:*.* ****. .. : . : ..*: :::* :. **. ****** :***:**:*:*:*.::**:************ **:*******::**** **:******:*********:******* ..* ** :*:.:*::******:** ****** *:****:******:*:* *:.* ::*::******************** :**:**** *. :***** ** *** ** :**:.*:::****:***:****************************:*:.***:::**:****** ***:**:***:.** **.******.**:: * ********:*:****: : : * :*.:. . * ..**:: ****.***********:*****:***:* ** *******:****. : **.******* ***:***::*: ** :::. . . * :.*.::*:.* *** :* *.****", "identical_positions": 495, "similar_positions": 374, "identity": "38.4%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1529", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2ARR6-1", "uniprot_id": "A2ARR6_MOUSE", "id": "A2ARR6-1", "name": "", "aln": "MDLVTYDDVHVNFTQEEWALLHPSQKSLYKGVMLETYRNLTAIGYIWEEHTIEDHFQTSRSHGRHERSCSAEQPPEFIQCGKAFAYESGRQRHQIKHTGGKHHDCNQCGKDFRTRNAPQIHKRTHTGEKPYDCNQYGKAFARISHLRVHKRTHTGEKPYECNQCGKAFASSSDLQKHKRTHTGEKPYECNQCGKAFAQSSHLRIHKRTHAGDKRYECNQCGKAFTQSNNLQIHKGTHAGEKRYECNQCGKAFASSSDLQKHKRTHTGEKPYECNQCGKAFAKSCDLQKHKRTHTGEKPYECKQCGKAFAISYTLQIHNRTHTGEKPYECKQCGKAFAQSSNLRIHKQTHTGERLYECN-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2AW66-1", "uniprot_id": "A2AW66_MOUSE", "id": "A2AW66-1", "name": "", "aln": "MDLVTYDDVHVNFTQEEWALLHPSQKSLYKGVMLETYRNLTAIGYIWEEHTIEDHFQTSRSHGRHERSCSAEQPPEFIQCGKAFAYESGRQRHQIKHTGGKHHDCNQCGKDFRTRNVPQIHKRTHTGEKPYDCNQYGKAFARISHLRVHKRTHTGEKPYECNQCGKAFASSSDLQKHKRTHTGEKPYECNQCGKAFAQSSHLRIHKRTHAGDKRYECNQCGKAFTQSNNLQIHKGTHAGEKRYECNQCGKAFASSSDLQKHKRTHTGEKPYECNQCGKAFAKSCDLQKHKRTHTGEKPYECKQCGKAFAVSYTLQIHNRTHTGEKPYECKQCGKAFAQSSNLRIHKQTHTGERLYECN-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2ARR8-1", "uniprot_id": "A2ARR8_MOUSE", "id": "A2ARR8-1", "name": "", "aln": "MNLITYDDVHVNFTQEEWALLDPSHKNLYKDVMVETYRNLTAIGYIWEEHTSEDHFQTSRSHGRHERSCSAEQPSEFIHCGKAFANESGSQRHQIKHTGEKQHDCNQCGKAFKRRSDLQIHKRTHTGEKPYECKQCGKAFSQSSHLRIHKRTHTGEKPYECKQCGKAFAQSSHLQIHKRTHTGEKPYECKQCGKAFAHSSHLHIHERTHTGEKPYECKQCGKGFARSGDLQKHKQTHTGEKPYECKQCGKAFSRKSVLQIHKRTHTGEKPYECKQCGKAFAQSSHLRIHKRAHTGLKPYECKQCGKAFAGSSGLQCHKRSHTGETPYECNQGGKPFEGSSGLEYNNRTQTAEKPYECNLCAKVLQEGVTFKEKRPYRRETL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB13A7D2-1", "uniprot_id": "A0AB13A7D2_DANRE", "id": "A0AB13A7D2-1", "name": "", "aln": "-----------------MAFIKEESEDIKIEETFTVKHEETEEAFRVKHEDPEEQTELMPLKDESQEQNETEETVQDEGCLDLRSGEASEQTETSQKTAES-NTCHHCGKSFTRKQYLTNHMRIHNGERPFKCHQCVKIFTQKQNFLDHMRIHTGEKPYTCQQCGKSFTWKRYLITHTRMHTGEKPYTCQECGKCFARKHMLTIHMRVHTGERPYPCQECGKGFTQKHILIDHMRIHTGERPHVCQQCGMSFTWKQYYTEHMRTHTGERPHACLQCGKNFTCKQNLTDHMRIHTGEKPFTCQQCGKCFTCKPNLRSHMKVHTGERPHACSQCGKSYPWKKNLKEHMRVHTGDQLSDANTSLIPM-----------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::. . :.: . . :: * .: :.. *:: : :.. :.. .:*:. : * . : *:. * . ::*. . : *::*** * :. * * *.**:*:.*:* * *:: .:: * * ******* *:****:*: . * *.* ******* *::***.**:. * ** *.*:*:: * *::***.*::. * * *:**: : *:*** :*: .. * ******:*: * **** *: . .* * * *** **: *:****.*: . *: * : **** *: *.* **.: ...*. : :.:*.:: :.* ", "identical_positions": 118, "similar_positions": 111, "identity": "30.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1531", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1B0GWX7-1", "uniprot_id": "A0A1B0GWX7_RAT", "id": "A0A1B0GWX7-1", "name": "V-type proton ATPase subunit", "aln": "MSFFPELYFNVDNGYLEGLVRGLKAGVLSQADYLNLVQCETLEDLKLHLQSTDYGNFLANEAS-PLTVSVIDDKLKEKMVVEFRHMRNHAYEPLASFLDFITYSYMIDNVILLITGTLHQRSIAELVPKCHPLGSFEQMEAVNIAQTPAELYNAILVDTPLAAFFQDCIS-EQDLDEMNIEIIRNTLYKAYLESFYKFCT-LLGGTTADAMCPILEFEADRRAFIITINSFG-TELSKEDRAKLFPHCGRLYPEGLAQLARADDYEQVKNVADYYPEYKLLFEGAGSNP-GDKTLEDRFFEHEVKLNKLAFLNQFHFGVFYAFVKLKEQECRNIVWIAECIAQRHRAKIDNYIPIF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51863-1", "uniprot_id": "VA0D1_MOUSE", "id": "P51863-1", "name": "V-type proton ATPase subunit d 1", "aln": "MSFFPELYFNVDNGYLEGLVRGLKAGVLSQADYLNLVQCETLEDLKLHLQSTDYGNFLANEAS-PLTVSVIDDKLKEKMVVEFRHMRNHAYEPLASFLDFITYSYMIDNVILLITGTLHQRSIAELVPKCHPLGSFEQMEAVNIAQTPAELYNAILVDTPLAAFFQDCIS-EQDLDEMNIEIIRNTLYKAYLESFYKFCT-LLGGTTADAMCPILEFEADRRAFIITINSFG-TELSKEDRAKLFPHCGRLYPEGLAQLARADDYEQVKNVADYYPEYKLLFEGAGSNP-GDKTLEDRFFEHEVKLNKLAFLNQFHFGVFYAFVKLKEQECRNIVWIAECIAQRHRAKIDNYIPIF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61421-1", "uniprot_id": "VA0D1_HUMAN", "id": "P61421-1", "name": "V-type proton ATPase subunit d 1", "aln": "MSFFPELYFNVDNGYLEGLVRGLKAGVLSQADYLNLVQCETLEDLKLHLQSTDYGNFLANEAS-PLTVSVIDDRLKEKMVVEFRHMRNHAYEPLASFLDFITYSYMIDNVILLITGTLHQRSIAELVPKCHPLGSFEQMEAVNIAQTPAELYNAILVDTPLAAFFQDCIS-EQDLDEMNIEIIRNTLYKAYLESFYKFCT-LLGGTTADAMCPILEFEADRRAFIITINSFG-TELSKEDRAKLFPHCGRLYPEGLAQLARADDYEQVKNVADYYPEYKLLFEGAGSNP-GDKTLEDRFFEHEVKLNKLAFLNQFHFGVFYAFVKLKEQECRNIVWIAECIAQRHRAKIDNYIPIF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PGV1-1", "uniprot_id": "VA0D1_DANRE", "id": "Q6PGV1-1", "name": "V-type proton ATPase subunit d 1", "aln": "-MPFSELYFNVDNGYLEGLVRGFKAGILSQADYLNLVQCETLEDLKLHLQSTDYGSFLANEAS-PLTVSVIDDKLKEKMVVEFRHMRNQSYEPLASFMDFITYSYMIDNVILLITGTLHQRAISELVPKCHPLGSFEQMEAVNIAQTPAELYNAILVDTPLAAFFQDCIS-EQDLDEMNIEIIRNTLYKAYLEAFYKFCT-TLGGTTADTMCPILEFEADRRAFIITINSFG-TELSKEDRAKLFPHCGKLYPEGLAQLARADDYEQVKAVAEYYPEYKLLFEGAGSNP-GDKTLEDRFFEHEVKLNKLAFLNQFHFSVFYAYVKLKEQECRNIVWIAECIAQRHRAKIDNYIPIF--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4P5-1", "uniprot_id": "VA0D1_DROME", "id": "Q9W4P5-1", "name": "V-type proton ATPase subunit d 1", "aln": "-MNSSGFMFNIDNGYLEGLCRGFKCGILKQADYLNLVQCETLEDLKLHLQGTDYGSFLANEPS-PLSVSVIDDKLREKLVIEFQHMRNHAVEPLSNFLDFITYGYMIDNIILLITGTLHQRPISELIPKCHPLGSFEQMEAIHVASTPAELYNAVLVDTPLAPFFVDCIS-EQDLDEMNIEIIRNTLYKAYLEAFYNFCK-NMGGATADVMCEILAFEADRRAIIITINSFG-TELSKDDRAKLYPNCGKMYPDGLAALARADDYEQVKTVAEYYAEYAALFDGSGNNP-GDKTLEDKFFEHEVKLDVYAFLQQFHFGVFYAYLKLKEQECRNIVWIAECVAQKHRAKIDNYIPIF--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32366-1", "uniprot_id": "VA0D_YEAST", "id": "P32366-1", "name": "V-type proton ATPase subunit d", "aln": "---MEGVYFNIDNGFIEGVVRGYRNGLLSNNQYINLTQCDTLEDLKLQLSSTDYGNFLSSVSSESLTTSLIQEYASSKLYHEFNYIRDQSSGSTRKFMDYITYGYMIDNVALMITGTIHDRDKGEILQRCHPLGWFDTLPTLSVATDLESLYETVLVDTPLAPYFKNCFDTAEELDDMNIEIIRNKLYKAYLEDFYNFVTEEIPEPAKECMQTLLGFEADRRSINIALNSLQSSDIDPDLKSDLLPNIGKLYPLATFHLAQAQDFEGVRAALANVYEYRGFLETG--------NLEDHFYQLEMELCRDAFTQQFAISTVWAWMKSKEQEVRNITWIAECIAQNQRERINNYISVY--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VCQ3-1", "uniprot_id": "VA0D2_DROME", "id": "Q9VCQ3-1", "name": "Probable V-type proton ATPase subunit d 2", "aln": "----MSMIFNTEYGYLEALTRGFKNGMLKHSDYLNLTQCESLEDVMISIQGTDYGLIFGGEQS-APSVEVIERCLRDRLLQQYYYIRSHSTEPLTTFMEFIRYPFMIDNVALLVAGLNNHRSMKRLLRMCHPLGEFDQLGAIEVASNSAELFDAVLIDTPIARFVPRDLP-MESLRYLDVEIVRAHLYRAYLEKFYAYCS-QLGGNTANVMTNLLSFEADRRTITIAVNAIG-SDIIPKERLKMFPTCGYLPKIALASMSTLNDTDKIRDVCNVFDGYGKMFDNLERDSDGMITLEDRFLMMEAKKNVQTFLQQYHFGIFYSFIKLKQLEVRNIVWISECIAQRQTDRINAFIPIPLD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ** : *::*.: ** : *:*.: :*:**.**::***: : :..**** ::.. * . :..:*: .:: :: ::*.:: . .*:::* * :****: *:::* :.* .:: ***** *: : :: :* .*::::*:***:* :. : :.* :::**:* **:**** ** : . : : : * :* ******:: *::*:: ::: . : .: * * : . :: :* : :: . * ::: .***:* * : :* :*: :. .::::* *: * ***.**:**:**.: :*: :*.: ", "identical_positions": 93, "similar_positions": 132, "identity": "25.98%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1534", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UIQ6-1", "uniprot_id": "LCAP_HUMAN", "id": "Q9UIQ6-1", "name": "Leucyl-cystinyl aminopeptidase", "aln": "MEPFTN---------DRLQLPRNMIENSMFEEEPDVVDLAKEPCLHPLEPDEVEYEPRGSRLLVRGLGEHEMEEDEEDYESSAKLLGMSFMNRSSGLRNSATGY-RQSPDGACSVPSARTMVVCAFVIVVAVSVIMVIYLLPRCTFTKEGCHKKNQSIGLIQPFATNGKLFPWAQIRLPTAVVPLRYELSLHPNLTSMTFRGSVTISVQALQVTWNIILHSTGHNISRVTFMSAVSSQEKQAEILEYAYHGQIAIVAPEALLAGHNYTLKIEYSANISSSYYGFYGFSYTDESNEKKYFAATQFEPLAARSAFPCFDEPAFKATFIIKIIRDEQYTALSNMPKKSSVVLDD-GLVQDEFSESVKMSTYLVAFIVGEMKNLSQDVNGTLVSIYAVPEKIGQVHYALETTVKLLEFFQNYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDSNTSSMADRKLVTKIIAHELAHQWFGNLVTMKWWNDLWLNEGFATFMEYFSLEKIFKELSSYEDFLDARFKTMKKDSLNSSHPISSSVQSSEQIEEMFDSLSYFKGSSLLLMLKTYLSEDVFQHAVVLYLHNHSYASIQSDDLWDSFNEVTNQTLDVKRMMKTWTLQKGFPLVTVQKKGKELFIQQERFFLNMKPEIQPSDTSYLWHIPLSYVTEGRNYSK-YQSVSLLDKKSGVINLTEEVLWVKVNINMNGYYIVHYADDDWEALIHQLKINPYVLSDKDRANLINNIFELAGLGKVPLKRAFDLINYLGNENHTAPITEALFQTDLIYNLLEKLGYMDLASRLVTRVFKLLQNQIQQQTWTDEGTPSMRELRSALLEFACTHNLGNCSTTAMKLFDDWMASNGTQSLPTDVMTTVFKVGAKTDKGWSFLLGKYISIGSEAEKNKILEALASSEDVRKLYWLMKSSLNGDNFRTQKLSFIIRTVGRHFPGHLLAWDFVKENWNKLVQKFPLGSYTIQNIVAGSTYLFSTKTHLSEVQAFFENQSEATFRLRCVQEALEVIQLNIQWMEKNLKSLTWWL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QDJ5-1", "uniprot_id": "A0A8M9QDJ5_DANRE", "id": "A0A8M9QDJ5-1", "name": "Leucyl-cystinyl aminopeptidase", "aln": "MESANHLNQQEYGAIERAPLPRNMIENSMFEEEPDVVDLAKESPSYHIDSDDVTYEPRSSRLLVRGLGENDMDEDEEDYESSARLLGMSFMNRSSSQRSAASSYTRQQPSNSCSPLSTKTTAVGVLILVLVVSMFMVIYFVPSCTFTKKGCQKSNSSMSSIYPISTSGELFPWTDLRLPVSVHPVHYNISLHPDLNSMTFQGNVSIVVLVVHETKNIVLHSSDMNIIKVTFD------DKEYRFLEYKPWQQIAIKFPEDLKKGQ-YVLKFSYKANLSNSYDGFYNSSYVDTAGTKRVLAATQFEPLAARKAFPCFDEPAFKSTFVVKMTREAKYISLSNMPKIKTTDLNENGLQEDEFESSVKMSTYLVAFIVAEFSSHSKNVSKTTVSVYAVPDKKDQVHYALETACKLLKFYNTFFEIEYPLSKLDLVAIPDFLAGAMENWGLITFRETTLLVG-NQSSRFDKQLVTSVIAHELAHQWFGNLVTMRWWNDLWLNEGFATYMQYMSIENVFPDLDIDIEFLNVRFKALAKDALNSSHPVSTFVSTPEQVEEMFDSVSYEKGASILLMLNATLRDGEFHKGVIEYLQNYNLSNTESKDLWNSLSQVSKQSLNVSEMMNTWTVHKGFPLVTVKRNGPQVTLSQEHFLLNAENGTDDS----LWHIPLTYVNDSCSVLRSCKQVFHLKDKEATLQLPGQVKWLKFNFRSDGFYIVHYDEQGWSDLISALKVDVNVLPSEDKAALINNIFALSRLGKVSFRQVLNLMDYIRNETETAPLTEALSQLGQIYRLLDKRSDLNLASSMTTYIESHFGSLMESQSWEVETSVSKMTLRSALLETACALNRPNCTTQARRLFDQWLASNKTLQIPSDLMRTVFKVAAKTDEGWSKLLGSYKHSIYDTEKRKMLEALASTQDVRKIIWVLQKSLDGSEIQNQEFPLVIHTVCRDFAGYLYAWDFMKENWEKITQKFPIGSFAIQSIITSTTSQFSTKTHLAEVQNFFSSLGAKGSQMRIVQEAIETIKHNMRWMEKNLNTLQSWL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. .: :* ***********************. : ::.*:* ****.**********::*:**********:***********. *.:*:.* **.*..:** *::* .* .:::*:.**::****::* *****:**:*.*.*:. * *::*.*:****:::***.:* *::*::****:*.****:*.*:* * .:: * **:***:. ** :*** :*: .:*** **** ** * *: *.**:.*.**:*.** ***. **.* :. *: :***********.***********:**::*: *: :* :****** .:. *:: ** :***..*************.*:.. *::*. * **:****:* .********: ***:*::.:***:***.********** *********:**** *** . * ** *::***.:****************:*************:*:*:*:*::* :*. :**:.***:: **:******:*: *.:.**:******:** **:*:****:: * :. *::.*: **:*:. :. :*.***:*:.:*::*:*:*..**:***::********:::* :: :.**:*:** : : * ******:**.:. . : :.* *..*...::*. :* *:*.*:. :*:***** ::.*. ** **:: **..:*:* ****** *: ****.:::.::*::*: **..***:**** * . **.**:* . ::*** :.* : . : . ::.*:* * : * ******* **: * **:* * :***:*:*** * .:*:*:* *****.****:*** ***.* ::**.*:******::****: *:::.**:*.:::.*::.::*:** *.*.*:* ****:****:*:.****:**::**.*::.:* *******:*** **.. . ::* ****:*.*: *::******::* **", "identical_positions": 556, "similar_positions": 315, "identity": "53.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1558", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PQL2-1", "uniprot_id": "CNOT9_RAT", "id": "Q5PQL2-1", "name": "CCR4-NOT transcription complex subunit 9", "aln": "-----------------------------MHSLATAAPVPTA-LAQVDR------------------------------------------------------EKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSIN-PPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSK-EPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQV-LKDDTTTKRWLAQLVKNLQEGQVTDPRGIPLPPQ--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKY0-1", "uniprot_id": "CNOT9_MOUSE", "id": "Q9JKY0-1", "name": "CCR4-NOT transcription complex subunit 9", "aln": "-----------------------------MHSLATAAPVPTA-LAQVDR------------------------------------------------------EKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSIN-PPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSK-EPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQV-LKDDTTTKRWLAQLVKNLQEGQVTDPRGIPLPPQ--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92600-1", "uniprot_id": "CNOT9_HUMAN", "id": "Q92600-1", "name": "CCR4-NOT transcription complex subunit 9", "aln": "-----------------------------MHSLATAAPVPTT-LAQVDR------------------------------------------------------EKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSIN-PPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSK-EPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQV-LKDDTTTKRWLAQLVKNLQEGQVTDPRGIPLPPQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NWL4-1", "uniprot_id": "CNOT9_DANRE", "id": "Q6NWL4-1", "name": "CCR4-NOT transcription complex subunit 9", "aln": "-------------------------------MLATGATVSTAGLAQVDR------------------------------------------------------EKIYQWINELSSPETRENALLELSKKRESVTDLAPMLWHSCGTIAALLQEIVNIYPSIN-PPTLTAHQSNRVCNALALLQCVASHVETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSK-EPSARLLKHVVRCYLRLSDNSRAREALRQCLPDQLKDTTFAQV-LKDDSTTKRWLAQLVKNLQEGQVTDPRGIPLPTQ--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLF2-1", "uniprot_id": "Q9VLF2_DROME", "id": "Q9VLF2-1", "name": "CCR4-NOT transcription complex subunit 9", "aln": "-------------------------------MSAEPSPVMSP-QQQAER------------------------------------------------------EKVYQLIIELAYPATRETALLELSKN--TYADLAPMLWKSVGTTCTLLQEIVNIYPIIT-TPVLKANQSNRVCYALTLLQCVASHPETRPAFLRDQIPMYLYPFLSTTFKSRPFEQLRLTTLGVINALAETGDTEVLIFLIWSEVVPHCLTNMVRGSKLTKIAATSILEKILLDEMGLTYICENHDRFSQVAITLGKMVIHMLK-FPCLRVLKHVVRCYLLLTENARARSALRVCLPDLLRDGTFTSL-VQHDTCTKQWLQMLLKNLQTNAVN-PMGSS------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53829-1", "uniprot_id": "CAF40_YEAST", "id": "P53829-1", "name": "Protein CAF40", "aln": "MFSAQKPIYGNGAGVNMGGGGPSTNNPGSMSMPGVPTSMGPGMNQQIPSGGPMLMGNTPNNNNSNENGENNGNNGNNGGNDANATRNNPNMVNNRGAVHALDDPNVYHWICQLTYGPQKEQALLELGRKREQFDDLAVVLWSSFGVMTSLLNEIISVYPMLQ-PQMLSNNLSNRVCNALVLLQCVASHPETKHLFLQAHIPLFLFPFLNTTSRQRTFEYLRLTSLGVIGALVKNDSQDVITFLLRTDIVPLCLRIMESSSELSKTVAIFILQKILLDDVGLQYICATLERFYAVTNVLKDMVEHLTVSTPPGRLLKHIIRCYLRLSDDLEARRLLKIVLPAKLRDNTFTEV-LRDDVGSKRCLAQLLLTLNEETS-------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9V9S3-1", "uniprot_id": "Q9V9S3_DROME", "id": "Q9V9S3-1", "name": "CCR4-NOT transcription complex subunit 9", "aln": "---------------------------------MSAPNMDCEQRGDIDS--------------------------------------------------------VFGWIANLCNKETRLWAMLELFERRTHIDSLGLLLWHSFGAVSGLLQEIVSIYPAIYQEIELTGQQSHRICTAIGLIQAMASHPFIGIQLIRCQFMCYLMPLLKMTSQTRAVEHVRLSVLGVICGLLKSDHPEIVSYFLGTELIPLTLRQLEFGTTMSKVLCAFVLYRTLEHEVGLKFASRRLARKLHLIHTLARVVHQLTL-EPEPRVLKHVVRIYSRLADHPQNLELILKLLPAQIRNGYFCQEGLVGFESASLELADLNRKLSKNEEKDKVCDDAMPENH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : :: * :* : *:*** .. .*. :** * *. **:**:.:** : *. : *:*:* *: *:*.:*** :: :: :* *:* . : *..* :**: **** .* :.. ::: ::: ::::* * : .: ::* . :* : * .: ** : . * : * :* :: * *:***::* * *::. . : ** ::: * . : :. * * .*. ", "identical_positions": 63, "similar_positions": 86, "identity": "16.24%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1565", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADE8-1", "uniprot_id": "D4ADE8_RAT", "id": "D4ADE8-1", "name": "RNA helicase", "aln": "MSHVAVENALGLDQQFAGLDLNSSDNQTGG--------STASKGRYIPPHLR----NREATK-------------------------------------------------------------------------------------------GFYDKDSSGWSS----------------SKDKDAYSSFGSRGDSRGK---------SSFFGDRG--------------SGSRGRFDDR-----------------------------GRGDYDGIGGRGDR----------------------------SGFGKFERG-------------------GNSRWCDKS-DEDDWSKPLPPSERLEQELFSG------GNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYADGPGEALRAMK-----ENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGAEIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEEIDKRSFLLDLLNATG------KDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV-----------------------AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLEN-MAFEHHYKGSSR-GRSKSSRFSGGFG---ARDYRQSSGASSSSFSSSRASSS---------------RSGGGGHGSSRGFGGGGYGGFYNSDGYGG--NYNSQGVDWWGN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62167-1", "uniprot_id": "DDX3X_MOUSE", "id": "Q62167-1", "name": "ATP-dependent RNA helicase DDX3X", "aln": "MSHVAVENALGLDQQFAGLDLNSSDNQSGG--------STASKGRYIPPHLR----NREATK-------------------------------------------------------------------------------------------GFYDKDSSGWSS----------------SKDKDAYSSFGSRGDSRGK---------SSFFGDRG--------------SGSRGRFDDR-----------------------------GRGDYDGIGGRGDR----------------------------SGFGKFERG-------------------GNSRWCDKS-DEDDWSKPLPPSERLEQELFSG------GNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYADGPGEALRAMK-----ENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGAEIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEEIDKRSFLLDLLNATG------KDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV-----------------------AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLEN-MAFEHHYKGSSR-GRSKSSRFSGGFG---ARDYRQSSGASSSSFSSSRASSS---------------RSGGGGHGGSRGFGGGGYGGFYNSDGYGG--NYNSQGVDWWGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00571-1", "uniprot_id": "DDX3X_HUMAN", "id": "O00571-1", "name": "ATP-dependent RNA helicase DDX3X", "aln": "MSHVAVENALGLDQQFAGLDLNSSDNQSGG--------STASKGRYIPPHLR----NREATK-------------------------------------------------------------------------------------------GFYDKDSSGWSS----------------SKDKDAYSSFGSRSDSRGK---------SSFFSDRG--------------SGSRGRFDDR-----------------------------GRSDYDGIGSRGDR----------------------------SGFGKFERG-------------------GNSRWCDKS-DEDDWSKPLPPSERLEQELFSG------GNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMK-----ENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATG------KDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV-----------------------AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLEN-MAYEHHYKGSSR-GRSKSSRFSGGFG---ARDYRQSSGASSSSFSSSRASSS---------------RSGGGGHGSSRGFGGGGYGGFYNSDGYGG--NYNSQGVDWWGN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P16381-1", "uniprot_id": "DDX3L_MOUSE", "id": "P16381-1", "name": "Putative ATP-dependent RNA helicase Pl10", "aln": "MSHVAEEDELGLDQQLAGLDLTSRDSQSGG--------STASKGRYIPPHLR----NREAAK-------------------------------------------------------------------------------------------AFYDKDGSRWS------------------KDKDAYSSFGSRSDTRAK---------SSFFSDRGG-------------SGSRGRFDER-----------------------------GRSDYESVGSRGGR----------------------------SGFGKFERG-------------------GNSRWCDKA-DEDDWSKPLPPSERLEQELFSG------GNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALRAMK-----ENGKYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEEADKRSFLLDLLNATG------KDSLILVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV-----------------------AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLEN-MAFEHHYKGGSR-GRSKS-RFSGGFG---ARDYRQSSGASSSSFSSGRASNS---------------RSGGGSHGSSRGFGGGSYGGFYNSDGYGG--NYSSQGVDWWGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62095-1", "uniprot_id": "DDX3Y_MOUSE", "id": "Q62095-1", "name": "ATP-dependent RNA helicase DDX3Y", "aln": "MSQVAAESTAGLDQQFVGLDLKSSDNQNGGG-------NTESKGRYIPPHLR----NRETSK-------------------------------------------------------------------------------------------GVCDKDSSGWSC----------------SKDKDAYSSFGSR-DSRGK---------PNYFSDRG--------------SGSRGRFDDH-----------------------------GRNDYDGIGGR-DR----------------------------TGFGKFERS-------------------GHSRWSDRS-DEDDWSKPLPPSERLEQELFSG------GNTGINFEKYDDIPVEATGNNCPPHIENFSDIEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAMK-----ENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADTVQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEELDKRSFLLDLLNATG------KDSLTLVFVETKKGADSLENFLFQERYACTSIHGDRSQKDREEALHQFRSGRKPILVATAV-----------------------AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNLNITKDLLDLLVEAKQEVPSWLES-MAYEHHYKGSSR-GRSKS-RFSGGFG---ARDYRQSSGSANAGFNSNRANSS---------------RSSGSSHN--RGFGGGGYGGFYNNDGYGG--NYNSQAVDWWGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A7A4-1", "uniprot_id": "A0A8I6A7A4_RAT", "id": "A0A8I6A7A4-1", "name": "RNA helicase", "aln": "---MAAENTVGLDQQFAGLDMNS-DNQNGGV-------STESKGRYIPPHLR----NRETSK-------------------------------------------------------------------------------------------GVCDKDNSGWS------------------KDKDAYSSFGSR-DSRGK---------PNYFSDRG--------------SGSRGRFDDP-----------------------------GRSDYDCIASR-DR----------------------------SGFGKFERS-------------------GYSRWGDKS-DEDDWSKPLPPSERLEQELFSG------GNTGINFEKYDDIPVEATGNNCPPHIENFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAMK-----ENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADTVQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEELDKRSFLLDLLNATG------KDSLTLVFVETKKGADSLENFLFQERYACTSIHGDRSQKDREEALHQFRSGRKPILVATAVCIFYFLVILSDCYFNLISIIFQVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNLNITKDLLDLLVEAKQEVPSWLES-MAYEHHYKGNSR-GRSK--RFSGGFG---ARDYRQSSGYANSGFNNNRANSS---------------RTSGSTHN--RGFGGGGYGGFYSNEGYGG--NYNSQAVDWWGN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15523-1", "uniprot_id": "DDX3Y_HUMAN", "id": "O15523-1", "name": "ATP-dependent RNA helicase DDX3Y", "aln": "MSHVVVKNDPELDQQLANLDLNS-EKQSGGA-------STASKGRYIPPHLR----NREASK-------------------------------------------------------------------------------------------GFHDKDSSGWSC----------------SKDKDAYSSFGSR-DSRGK---------PGYFSERG--------------SGSRGRFDDR-----------------------------GRSDYDGIGNR-ER----------------------------PGFGRFERS-------------------GHSRWCDKS-VEDDWSKPLPPSERLEQELFSG------GNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVK-----ENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATG------SDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV-----------------------AARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLEN-MAYEHHYKGGSR-GRSKSNRFSGGFG---ARDYRQSSGSSSSGFGASRGSSS---------------RSGGGGYGNSRGFGGGGYGGFYNSDGYGG--NYNSQGVDWWGN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QFI7-1", "uniprot_id": "A0A8M9QFI7_DANRE", "id": "A0A8M9QFI7-1", "name": "RNA helicase", "aln": "MSHVVVDGSHGLDQQLAVLDLNSADGQGVG-----------TGRRYIPPHLR----NKDASKNAGNAYSSGRQSGYSVAPVQSFSPKQYPQSWHPEGNQRHRQNYPTGWNDFRTGNYLEKADLLLRSSICEGMVVLSALYFCLGSQRFASQELAFYHTYTSGWPDRCASPARTDSSVATDGNEDTASVISWADRCDSPGWDGSRTNGFVNGYHDSRMNGTANFARGPLRNDRGGRGGFRGNRNGASFNQPVHNAGYGTYENKDGGWNSVVNRDAYASFGGRSDRG-----------------KSAFFNDRGASSRGRYERGGFGGGT------------GGNSRWVEESRDEEDWSKPMPPNERLEHELFSA------SNTGINFEKYDDIPVEATGTNSPGHIESFHDVDMGEIIMGNITLSRYTRPTPVQKYAIPIIKTKRDLMACAQTGSGKTAAFLLPVLSQIYSEGPGEALQATKASTQQENGKYVRRKQYPISLVLAPTRELALQIYDEARKFAYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDYCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGSRQTMMFSATFPKEIQILARDFLEEYIFLAVGRVGSTSENITQKVVWVEENDKRSFLLDLLNATG------KDSLTLVFVETKKGADALEDFLYREGYACTSIHGDRSQRDREEALHQFRSGRCPIMVATAV-----------------------AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFYNDKNSNITKDLLDILVEAKQEVPSWLEN-LAYEHQHKSTNR-GRPK--RFSGGFG---ARDYRQMPGGGNT-FGNRGARNTGGHGGN---------RGFGGNKGGFGSFGGDSYGGTYGN--YGG--NYT--QVDWWGN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHP0-1", "uniprot_id": "DDX3_DROME", "id": "Q9VHP0-1", "name": "ATP-dependent RNA helicase bel", "aln": "MSNAINQNGTGLEQQVAGLDLNGGSADYSGPITSKTSTNSVTGGVYVPPHLRGGGGNNNAADAESQ---------------------------------------------------------------------------------------GQGQGQGQGFDSRSGNPR----------QETRDPQQSRGGGGEYRRGGG----GGGRGFNRQSGDYG---YGSGGGGRRGGGGRFEDNYNGGEFDSRRGGDWNRSGGGGGGGRGFGRGPSYRGGGGGSGSNLNEQTAEDGQAQQQQQPRNDRWQEPERPAGFDGSEGGQSAGGNRSYNNRGERGGGGYNSRWKEGGGSNVDYTKLGARDERLEVELFGV------GNTGINFDKYEDIPVEATGQNVPPNITSFDDVQLTEIIRNNVALARYDKPTPVQKHAIPIIINGRDLMACAQTGSGKTAAFLVPILNQMYELGHVPPPQSTR--------QYSRRKQYPLGLVLAPTRELATQIFEEAKKFAYRSRMRPAVLYGGNNTSEQMRELDRGCHLIVATPGRLEDMITRGKVGLENIRFLVLDEADRMLDMGFEPQIRRIVEQLNMPPTGQRQTLMFSATFPKQIQELASDFLSNYIFLAVGRVGSTSENITQTILWVYEPDKRSYLLDLLSSIRDGPEYTKDSLTLIFVETKKGADSLEEFLYQCNHPVTSIHGDRTQKEREEALRCFRSGDCPILVATAV-----------------------AARGLDIPHVKHVINFDLPSDVEEYVHRIGRTGRMGNLGVATSFFNEKNRNICSDLLELLIETKQEIPSFMED-MSSDRGHGGAKRAGRGGGGRYGGGFG---SRDYRQSSGGGGGGRSGPPPRSGGSGSGGGGGSYRSNGNSYGGNSGGGGYYGGGAGGGSYGGSYGGGSASHSSNAPDWWAQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06634-1", "uniprot_id": "DED1_YEAST", "id": "P06634-1", "name": "ATP-dependent RNA helicase DED1", "aln": "--------MAELSEQVQNLSIND--NNENG---------------YVPPHLR---------------------------------------------------------------------------------------------------------------------------------GKPRSARNNSSNYNNNNGG-----------YNGGRG----------------GGSFFSNN-----------------------------RRGGYGNGGFFGGN----------------------------NGGSRSNGR-------------------SGGRWIDGK------HVPAPRNEKAEIAIFGVPEDPNFQSSGINFDNYDDIPVDASGKDVPEPITEFTSPPLDGLLLENIKLARFTKPTPVQKYSVPIVANGRDLMACAQTGSGKTGGFLFPVLSESFKTGPSPQPESQG--------SFYQRKAYPTAVIMAPTRELATQIFDEAKKFTYRSWVKACVVYGGSPIGNQLREIERGCDLLVATPGRLNDLLERGKISLANVKYLVLDEADRMLDMGFEPQIRHIVEDCDMTPVGERQTLMFSATFPADIQHLARDFLSDYIFLSVGRVGSTSENITQKVLYVENQDKKSALLDLLSAST-------DGLTLIFVETKRMADQLTDFLIMQNFRATAIHGDRTQSERERALAAFRSGAATLLVATAV-----------------------AARGLDIPNVTHVINYDLPSDVDDYVHRIGRTGRAGNTGLATAFFNSENSNIVKGLHEILTEANQEVPSFLKDAMMSAPGSRSNSR---------RGGFGRNNNRDYRKAGGASAGGWGSSRSRDN-------------------------SFRGGSGWGSDSKSSGWGN--SGGSNNSSWW--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.:*. *.:.. : * *:***** : . . .. : : . . * . . . . . : .** : . .*: * :*. .:****::*:****:*:* : * * .* . : :: *: *:*: :******:::**: **************..**.*:*.: : * .: : :** ** .:::******* **::**:**:*** ::..*:*** :*:*:::***.*:******* *:: ***:.* ::*******************:***: *.* * *:*:******* :** ** ***.:****:*************.:::* : **:* ***:*.: *.* *:*****: ** * :** . *:*****:* :**.** **** .::***** *******.:* ****:*****:::********** ** *:**:*:*..* ** ..* ::* *::**:**:::. : . .* **** ****: * . . . **.. *. . *. . .** ", "identical_positions": 261, "similar_positions": 155, "identity": "27.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1566", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPH0-1", "uniprot_id": "S26A5_RAT", "id": "Q9EPH0-1", "name": "Prestin", "aln": "-----------------------MDHAEENEIPAETQKYLVERPIFSHPVLQ-ERLHV----------------KDKVTDSIGDKLKQAFTCTPKKVRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFA-MLAAVPPVFGLYSSFYPVIMYCFFGTSRHISIGPFAVISLMIGGVAVR-----------------------------LVPDDIVIPGGVNATNGT--EARDA-------LRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTS------MLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGG-KEFNERFKEKLPAPIPLEFFAVVMGTGISAGFNLHESYSVDVVGTLPLG-----LLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGICNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFS-DLPFFWRTS-KIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYTVLGQLPDT-----------DVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSSALKRKTGVNPAIIMGARRKAMRKYAKEVGNANIAN---------ATVVKVDAEVDGENATKPEEEDDEVKFPPIVIKTTFPEELQRFLPQGEN-IHTVILDFTQVNFMDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTSNRFFENPALKELLFHSIHDAVLGSQVREAMAEQETTVLPPQEDMEPNATPTTPEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99NH7-1", "uniprot_id": "S26A5_MOUSE", "id": "Q99NH7-1", "name": "Prestin", "aln": "-----------------------MDHAEENEIPAETQRYYVERPIFSHPVLQ-ERLHV----------------KDKVTESIGDKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFA-MLAAVPPVFGLYSSFYPVIMYCFFGTSRHISIGPFAVISLMIGGVAVR-----------------------------LVPDDIVIPGGVNATNGT--EARDA-------LRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTS------MLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGG-KEFNERFKEKLPAPIPLEFFAVVMGTGISAGFNLHESYSVDVVGTLPLG-----LLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGICNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFS-DLPFFWRTS-KIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGQLPDT-----------DVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSSALKRKTGVNPALIMGARRKAMRKYAKEVGNANVAN---------ATVVKVDAEVDGENATKPEEEDDEVKFPPIVIKTTFPEELQRFLPQGEN-VHTVILDFTQVNFVDSVGVKTLAGIVKEYGDVGIYVYLAGCSPQVVNDLTRNNFFENPALKELLFHSIHDAVLGSQVREAMAEQEATASLPQEDMEPNATPTTPEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58743-1", "uniprot_id": "S26A5_HUMAN", "id": "P58743-1", "name": "Prestin", "aln": "-----------------------MDHAEENEILAATQRYYVERPIFSHPVLQ-ERLHT----------------KDKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFA-MLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVR-----------------------------LVPDDIVIPGGVNATNGT--EARDA-------LRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTS------MLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGG-KEFNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLG-----LLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFS-DLPFFWRTS-KIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPET-----------DVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMAN---------ATVVKADAEVDGEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGDN-VHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFFENPALWELLFHSIHDAVLGSQLREALAEQEASAPPSQEDLEPNATPATPEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T2C4-1", "uniprot_id": "S26A5_DANRE", "id": "Q7T2C4-1", "name": "Prestin", "aln": "-----------------------MEHVTVSEEPSATLMYHVERPIFSEAYIDSELLHK----------------RKKTPKPYKLRVAEHLCCSSEKVKSVVFGFLPILTWLPSYPLKEYLFGDIVSGISTGVMQLPQGLAYA-MLAAVPPVFGLYSSFYPVLLYTFFGTSKHISIGTFAVISLMIGGVAVR-----------------------------EAPDSMFMVNGTNSSLVVNIEARDS-------RRVEVVVALTTLVGIIQFVLGLLRFGFLAIYLTEPLVRGFTTAAAVHVSVS------QLKYLLGVKTARFNGPLSVVYSLDAVLRNIADTNIVTLIIGLGCTVFLYII-KQLNERFKKKLLIPIPGEIIVVIVSTGISYGMLMSENYGVDVVGKIPTG-----LLPPKVPDFSVFPNLFADAVPIAVVGFSITISLAKTFALKYGYSVDGNQELIALGLCNFVSSFFHTFVVTASMSRSLVQESTGGHTEIAGLLASLLVLLVVVAIGFVFQPLPTTVLAAIIMVNLLGMFKQTR-DIPVLWRKS-KIELAIWLVSFFASVLLGLDYGLAVAMAFAILTVIYRTQRPKNVVLGQIPDT-----------GLYFDVDEYEEAEECSGIKIFQSNSSIYFANSELYVKALKAKTGIDPEKLLDAKKLQLKYAKRDTEGTKTVNQGSLLKKNAVVLLDMELGVTHEVLNGPQKPKHVHTNGQMTEKHIESESEDEFFLQRLTPIHSVILDFTPVNFIDSVGAKTIKSVIKEYATVDVKVVLAGCSRTLLSELRTLQFFSEPVTPDLIFPTIHDAVLQCKRWRDLPVHPNIH------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVM6-1", "uniprot_id": "Q9VVM6_DROME", "id": "Q9VVM6-1", "name": "", "aln": "--------MPSDKESPETKPLNNNNTNGNGGSVPSKPKIQPKYSIHRDVLTHEVVIKQ----------------TGYAARDKSIPSSLRNCWRSWNFFALFTGVIPILQWLPQYSPRRDLPGDIIAGFTVAIMNIPHGMAYG-ILAGVSAGNGLYMAVFPVLAYMFLGTSKHISIGTFAVASMMTAKVVDTYANVDDHHQILPINAFGLQSNGTATASPLLLINSSALADSVSSTTISPFQLLNSTLNADPITKIEVATSLALTVGIVNLLMAFLRLGTLSSLLSEPLVNGFTTAAACHVVTA------QLKDVLGISVPRHKGAFKIIYTVIDVIKGVPQTNLVNFGFCMAVIAFMMICNEILKPRLSKKCRFPLPAELIMVIGGTLISKWFNLYVDYNVNPVGKIPSG-----LPEPVLPRLDLVPKVAVDSIAIAIVTYSIIMSMGLTFAKKHGYEVRPNQELFAMGIGNMVGGCFSCIPMACSLSRSVIQDQTGGVSQIASLVSASLVVVTLMWIGPFFSSLPRCVLAGVIIVALKPMFMQAK-ELKKFSKQG-KLEMFTWISTFLCVVIIDIDIGLLIGICISLLALYIKGLKPYSCLLGYMPEAP----------GIYMDLNQHRNAMQVPEVRIFRYSGSLNFATSLFFRRALYEAVGLD-----------------------------------------KIPLTKVSSSNSNSPSKGSKSSYSPVSQNGGKAINGKLEETSGAFKVLVLDFSMLGHIDVAGCRTLTDLSKELKVRGARLLLASPVDRVYDTLVHSMALSE--GPFEIFPTLHDCVEYANACRTA-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53394-1", "uniprot_id": "SULX_YEAST", "id": "P53394-1", "name": "Putative sulfate transporter YPR003C", "aln": "MTSNNSLLGRGRMSYSSTAPPRFKRSVDQRDTFSDNFDYDKDSSNRGRTYIAASNSTTGVPPPNNSRSGCTNNTNNTNNTSNTSNTNNNDSVDENTVFETLPYYLPCFSWLPEYTFN-KLWGDVIAGISVASFQIPLALSYTTSIAHVPPLCGLYSLAISPFVYGILGSVPQMIVGPESAISLVVGQAVES--------------------------------------ITLHKENVS---------------LIDISTVITFVSGTILLFSGISRFGFLGNVLSKALLRGFISSVGLVMIINSLISELKLDKFLVSLPQHYHTPFEKILFLIDYAPAQYHIPTAIFSGCCLIVLFLTRLLKRKLMKYHKSAIF-FPDILLVVIVTILISMKFNLKHRYGISIIGDFSMDNFDELKNPLTRPRRKLIPDLFSASLIVAMLGFFESTTASKSLGTTYNLTVSSNRELVALGFMNIVISLFGALPAFGGYGRSKINALSGAQSVMSGVFMGVITLITMNLLLQFVHYIPNCVLSVITTIIGISLLEEVPGDIKFHLRCGGFSELFVFAVTFCTTIFYSIEAGICIGCVYSIINIIKHSAKSRIQILARVAGTSNFTNLDDYMMNMKRNSLDVEGTEEIEGCMIVRIPEPLTFTNSEDLKQRLDRIERYGSS-------------------------------------KIHPGRKSLRSKDSIKYVIFDLGGMTSIDSSAAQVLEEIITSYKR--RNVFIYLVNVSINDKVRRRLFKAGVAASVERAQANNNENNTSNTFSDAGETYSPYFDSIDAALYEIEKMKIKGNNVPNNDSESFMSNTLFNSSLV----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . .. . :* *** * . : **:::*::.. :::* .::: :* *.. *** . : * ::*: :: :*. :. *:: . .. :.: :: * : : .. *:* :. *::.*:.** ::.. : *. .: :. :. : . : :: : : :. :* :: *: ** : : *.:. :* :. . * .:. : :: :*:: : : . ::. .:. * *:**.*:*: * : . * : . .** :: :*. : ::. . . : ::.: .. :* **: : : :: : :: : . *: : :* :: .:: *: . ::: : : . :*. :. : .: : . . : *.: .: ::.* * . . . . . . : : : : :.: : :. * . : : . . :: : : : . ", "identical_positions": 56, "similar_positions": 210, "identity": "6.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1571", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZPF4-1", "uniprot_id": "FMNL3_MOUSE", "id": "Q6ZPF4-1", "name": "Formin-like protein 3", "aln": "MGNLESTDGGPGEPPSVPLLLPPG--------------------------------------------------KTPMPEPCELEERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPNVTR----------KKFRRRVQEST--KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSF-------------AQCSVMFDFEGLESGDDGAFDKLRSWSRSIED----LQPPNALSAPFTNSLARSARQSVLRYSTLP--------------GRRALKNSRLVSQKDDVHVCILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKELHRFEKLMEYFRN-EDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSNQVHTLRRLIKEKEEAFQRR-CHLEPSARGLESMGG----------EALARVGP-TELTEGIPPSDLDLLAP------------APPTEETLPLPPPPAPPLPPPPPP---------------LPDKCPPAPPLPGAAPSVVLTVGLS-----AIRIKKPIKTKFRLPVFNWTALKPNQINGTVFSELDDEKILEDLDLDRFEELFKTKAQGPALDLICS-------KNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPELANFWQELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDN----SVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQ---------QQELIAELRRR----QAKEHRPVYEGKDGTIEDIITVLKSVPFT-ARTAKRGSRFFCDAAHHD----ESNC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ART4-1", "uniprot_id": "A0A8I6ART4_RAT", "id": "A0A8I6ART4-1", "name": "", "aln": "MGNLESTDGGPGEPPSVPLLLPPG--------------------------------------------------KTPMPEPCELEERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPNVTR----------KKFRRRVQEST--KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSF-------------AQCSVMFDFEGLESGDDGAFDKLRSWSRSIED----LQPPNALSAPFTNSLARSARQSVLRYSTLP--------------GRRALKNSRLVSQKDDVHVCILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKELHRFEKLMEYFRN-EDSNIDFLVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSNQVHTLRRLIKEKEEAFQRR-CHLEPSARSLESMGGS---------EALARVGP-TELTEGSTPSDLDLLAP------------APPAEETLPLPPPPAPPLPPPPPP---------------LPDKCPPAPPLPGAAPSVVLTVGLS-----AIRIKKPIKTKFRLPVFNWTALKPNQINGTVFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICS-------KNKTAQKAASKVTLLEANRAKNLAITLRKAGRTAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPELANFWQELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDN----SVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQ---------QQELIAELRRR----QAKEHRPVYEGKDGAIEDIITVLKSVPFT-ARTAKRGSRFFCDAAHHD----ESNC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IVF7-1", "uniprot_id": "FMNL3_HUMAN", "id": "Q8IVF7-1", "name": "Formin-like protein 3", "aln": "MGNLESAEGVPGEPPSVPLLLPPG--------------------------------------------------KMPMPEPCELEERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTR----------KKFRRRVQEST--KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSF-------------AQCSVMFDFEGLESGDDGAFDKLRSWSRSIED----LQPPSALSAPFTNSLARSARQSVLRYSTLP--------------GRRALKNSRLVSQKDDVHVCILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKELHRFEKLMEYFRN-EDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRR-CHLEPNVRGLESVDS----------EALARVGP-AELSEGMPPSDLDLLAP------------APPPEEVLPLPPPPAPPLPPPPPP---------------LPDKCPPAPPLPGAAPSVVLTVGLS-----AIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICS-------KNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDN----SVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQ---------QQELIAELRRR----QAKEHRPVYEGKDGTIEDIITVLKSVPFT-ARTAKRGSRFFCDAAHHD----ESNC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NXC0-1", "uniprot_id": "FMNL3_DANRE", "id": "Q6NXC0-1", "name": "Formin-like protein 3", "aln": "MGNIESVDG----QSEMKHHIMPL--------------------------------------------------KVPMPDPTELEERFAIVLNSMNLPPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLRGYLDPKVTR----------KKFRRRVQEST--KVLRELEISLRTNHIGWVREFLNDENRGLDILVEYLSF-------------AQCAVMLDFEGLENGEDFSLDKAKSWSRSIED----LHQNG------CNTLVRSARQSVLRYGSTS--------------NSKTIKNSRLVSQKDDVHVCIMCLRAIMNYQYGFNLVMSHAHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCKEKHRFEKLMEYFRS-EDGNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLDDFLEKSKHTESDKLSVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHLSHVTEKLLDVENETMTKVADLEKQLLHKDKELAVIKETYESASTQVHTLRRMIQEKDAAFQRH-NNIEKQLLELEQQGTIRLRKQPDGDIAIETLG--AGAVAGTPLTDLRSLTVGMSTIGGLGGTSAVPVEAVAPPPPPPPPPPPPPPAPPLP-------SEVESIPIPPPPPPPLPGPSPSVILSVGLS-----AIRIKKPIKTKFRLPVFNWTALKPNQINGTVFNEIDDDRVLEELDLEKFEELFKTKAQGPVVDLSCS-------KSKVSQKVINKVQLLDANRSKNLAITLRKANKTTEEICKAIQTFDLKALPVDFVECLMRFLPTEAESKLLRQYERERRPLDQLAEEDRFMLLFSKIERLTQRMSIITFVGNFNDNVNMLTPQLNAIIAASASVKSSPKLKKILEIILALGNYMNSSKRGSVYGFKLQSLDLLLDTKSTDRKMTLLHYIALVVKEKYPELANFYNELHFVDKAAAVSLENVLLDVKELGKGMDLVRRECSLHDH----AVLKGFAQTSDTQLDKLAKDAKTAEEAFNNVVLYFGESPKTTPPSVFFPVFVRFIRAYKEAVEENEQRKKQEEAMREKLLAQEAKQHDPKVQAQKKRHQ---------QQELIAELRRR----QAKDHRPVYEGKDGTIEDIITVLKSVPFT-ARTAKRGSRFFCDANLFD----ESIC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUC6-1", "uniprot_id": "FRL_DROME", "id": "Q9VUC6-1", "name": "Formin-like protein", "aln": "MGAVKSRTITSADVDADEQLQHPHSHAHHHSMRNGHQHNGSISSGTLQKQDLRYDIGCSSQYQHVRQPSLRSRSQQPMPTTDELDRRFAKVLASMDLPPDKAKLLRNYDDEKKWDMICDQEMVQAKDPPSHYLSKLRTYLDPKASRSHRLYLFYFLCQKRKMVGESTSTQVLRDLEISLRTNHIEWVKEFLDDTNQGLDALVDYLSFRLQMMRHEQRLQGVLCASEERLNLTNGGDGGEIVMGNSSSVSPGGGGGLLSHGNSTGHGLANGTLDSRQQHTMSYGFLRPTIADALDSPSLKRRSRHIAKLNMGAATDDIHVSIMCLRAIMNNKYGFNMVIQHREAINCIALSLIHKSLRTKALVLELLAAICLVKGGHEIILGSFDNFKDVCQEKRRFQTLMEYFMNFEAFNIDFMVACMQFMNIVVHSVEDMNYRVHLQYEFTALGLDKYLERIRLTESEELKVQISAYLDNVFDVAALMEDSETKTSALERVQELEDQL----EREIDRNSEFLYKYAELESESLTLKTEREQLAMIRQKLEEELTVMQRMLQHNEQELKKRDTLLHTKNMELQTLSRSLPRSASSGDGSLANGGLMAGSTSGAASLTLPPPPPPMP--------ASPTASSAAPPPPPPPAPPAPPPPPGFSPLGSPSGSLASTAPSPPHAPPMLSSFQPPPPPVAGFMPAPDGAMTIKRKVPTKYKLPTLNWIALKPNQVRGTIFNELDDEKIFKQIDFNEFEERFKIGIGGALRNGSNGTEVDGSLQSSKRFKRPDNVSLLEHTRLRNIAISRRKLGMPIDDVIAAIHSLDLKKLSLENVELLQKMVPTDAEVKSYKEYIIERKDQQLLTEEDKFMLQLSRVERISSKLAIMNYMGNFVDSVHLISPQVQSIAGASTSLKQSRKFKAVLEIVLAFGNYLNSNKRGPAYGFKLQSLDTLIDTKSTDKRSSLLHYIVATIRAKFPELLNFESELYGTDKAASVALENVVADVQELEKGMDLVRKEAELRVKGAQTHILRDFLNNSEDKLKKIKSDLRHAQEAFKECVEYFGDSSRNADAAAFFALIVRFTRAFKQHDQENEQRLRLEKAAALAASKKENDQVLMRNKVNQKKQQLPSNGALSLQEAVINELKSKAHSVREKKLLQQDEVYNGALEDILLGLKSEPYRRADAVRRSQRRRIDNNRLSRTLEEMDC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ::* * : *** . **:.*** ** **:******:***:**:*****:***** .*.*:** *:.**: :***..:* : *: * *** :***:********** **:***:* *:*** **:**** . *: :: :.*:. : .* * * . * . * * :* .: *. : : : .: : .**:**.*:******* :****:*:.* .*:* ***** :*. ************:***:*******.:*****:**:* :**:.***** . * ****:******:***********:********* ***:.:*:: : ***::*.***.*********..*:**:***. ***:*:***::: *: :* :.* : : *:**.: * ..* : :. . :: .::*:::.:: :::: :. . *: . :: * : * . * . : . . . * ****..* .***.* * ..* *.. *. .*: *: **: : **::**.:** ******: **:*.*:**:::::::*::.*** ** *. : . :.. * .:* **: .* :*:**: ** . . ::: **:::**: *.:: ** * :::**:** * ::* **: : *: **:*** :*::**::.::: : ::*** *.:::::**:::* .**:*:*.* *:* :***:**:***:**.***..********* *:******:: :***:*. .:: *:*:* ** **: .:***:*:****: **:** :**:*:*:*..:: : :*:.* ...: :*.*: * : *:**:: * ***:*.:.: .:.**.::*** *::*: :*** * : *:. :* .: : :::: * *: :* **: : : *. * :*::***: *** *: * :.:*..* * . * *", "identical_positions": 428, "similar_positions": 324, "identity": "35.82%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1574", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1L1K3-1", "uniprot_id": "APC5_RAT", "id": "A1L1K3-1", "name": "Anaphase-promoting complex subunit 5", "aln": "-------------MMTNGVVHANLFGIKDWVTP--------------YKIAVLVLLNEMGR------TGEGAVSLVERRKLNQLLLPLLQGPDITLSKLYKLIEESCPQLAN----SVQIRIKLMAEGELKDLEQFFDDL-SDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNG------EKKTVEDADMD---REDGER-QMEKEELDV-SVREEEVSCS----GPLSQ---KQAEFFLSQQAALLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSS-THSLLHYFDRL-ILTGAEGKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKR-ADSYVLLEHSVKKAVHFGLP-------------RAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLESLSAGVQQNNTESFAVALCHLAELHAEQGCFAAAGEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKFHLADSLVTGITALNGIEGVYRKAVVLQAQNQMTEAHKLLQKLLTYCQKLKNTEMVISVLLSVAELYWRSSSPTIAMPVLLEALALSKEYRLQYLASETVLNLAYAQLILGIPEQALTLLHMAIEPILADGAILDKGRAMFLVSKCQVASAASYDPVKKAEALEAAIQNLTEAKNYFAKVDCRERIRDVSYFQARLYHALGKTQERNHCAMVFRQLHQELPSHGVPLINHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BTZ4-1", "uniprot_id": "APC5_MOUSE", "id": "Q8BTZ4-1", "name": "Anaphase-promoting complex subunit 5", "aln": "-------------MMTNGVVHANLFGIKDWVTP--------------YKIAVLVLLNEMGR------TGEGAVSLVERRKLNQLLLPLLQGPDITLSKLYKLIEESCPQLAN----SVQIRIKLMAEGELKDMEQFFDDL-SDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNG------EKKTVEDADMD---REDGEK-QMEKEELDV-SVREEEVSCS----GPLSQ---KQAEFFLSQQAALLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSS-THSLLHYFDRL-ILTGAEGKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKR-ADSYVLLEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLESLNAGVQQNNTESFAVALCHLAELHAEQGCFAAAGEVLKHLKDRFPPNSQHAQLWMLCDQKIQFDRAMNDGKFHLADSLVTGITALNGIEGVYRKAVVLQAQNQMTEAHKLLQKLLTYCQKLKNTEMVISVLLSVAELYWRSSSPTIAMPVLLEALALSKEYRLQYLASETVLNLAYAQLILGIPEQALTLLHMAIEPILADGAVLDKGRAMFLVSKCQVASAASYDPVKKAEALEAAIQNLSEAKNYFAQVDCRERIRDVAYFQARLYHALGKTQERNHCAMIFRQLHQELPAHGVPLINHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJX4-1", "uniprot_id": "APC5_HUMAN", "id": "Q9UJX4-1", "name": "Anaphase-promoting complex subunit 5", "aln": "-MASVHESLYFNPMMTNGVVHANVFGIKDWVTP--------------YKIAVLVLLNEMSR------TGEGAVSLMERRRLNQLLLPLLQGPDITLSKLYKLIEESCPQLAN----SVQIRIKLMAEGELKDMEQFFDDL-SDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNG------EKKTVEDADMELTSRDEGER-KMEKEELDV-SVREEEVSCS----GPLSQ---KQAEFFLSQQASLLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSS-THSLLHYFDRL-ILTGAESKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKR-SDSYVLLEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQGCFAAASEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNSIEGVYRKAVVLQAQNQMSEAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIALPMLLQALALSKEYRLQYLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILDKGRAMFLVAKCQVASAASYDQPKKAEALEAAIENLNEAKNYFAKVDCKERIRDVVYFQARLYHTLGKTQERNRCAMLFRQLHQELPSHGVPLINHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PFK7-1", "uniprot_id": "A0A8M1PFK7_DANRE", "id": "A0A8M1PFK7-1", "name": "Anaphase-promoting complex subunit 5", "aln": "-MASVHESLYFNPMMTNGVVHANIFGIKDWVTP--------------YKIAVLALLYEMST------TKP--MALLDRRRLNKLILPLQQGPDLTLEQFLKIVEECCLRMVN----AVKLRLFLMADGELQDMEHFFTIL-PSAFSDSEP--FKTSVVGLFMRQMLLAYNKLSFSQVYKLYKSLQQFCHRGN---QPELSALPAEDMELTSNEDPSADHIDKDELDTPSLHQSELSRSEESQGPLSQ---KQAEYFLARQAYLLKNDENKAMSPAKLQDELNNILKFNPDFAEAHYLSYLNSLRVQDIYIS-THSLLHYFDRL-ILSGAEGKSNGDEGYGRSLRYAVLNLATLHCRFGHYHQADLALQEAIRIAQEANDHVCLQHCLSWLYTLEQMRGSDSVVLTEDSVKIAAHFCLPYLASLGIQSLVQQGAKQGMPANKLLDALRGTDIMHWKQSLSELIEISLAQTTSIWRMYGKSTMAQQQAQLLLNMNSLEPVNFSVQQNNTEAFAVALCHLAELHAEQGLYPVVTDIMKHLKQQFPPHTQHAKLWMLCDLKIQFEKAMNDGKYHLAEPHVTAITALNSTEGMYRKAQLLKALNQTTEASKILQQLQQQCEKSKNTQMSIRVMLASAELHWDSSGFATALPLLLQALALSRQHNLQSLTSETLLHLAFTQLMLGISEQALGLVQDVLESVLAHGSLMDKGRALLLAARCQMASAGAAAQEHRLSAVELAVHTLDEAAVYFSRLDCKERMRDIYYLQARLHQTLGNISQRNRCAMLFRLLDQELPSSRMTVVNRL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZL2-1", "uniprot_id": "Q9VZL2_DROME", "id": "Q9VZL2-1", "name": "Anaphase-promoting complex subunit 5", "aln": "MILCLHFAGKSKIGFRGPKLTMNLFEELDTLDPSFKLEPPRIETPTAHKITVLILLKQYVINKKNCLDTGISMRTQRRRMFYMLVFKLIQEQDKSYNELHSLLTTGKYKLDTLMLESFEKAMSEFCAGSIEALFDFSEIQNIDEILNENYGISQFSMVGVYVRRVGVVLERLSFPEMMDMYKNVCSYYERGVRAAASGSRMAVAGGILHREETPPPNPITEKPEDPKPKKKVEAVARIAQERNPLSKWAPKQAKFFINKQSELLENNERKALPPLELQKKVQEIIHDLPLTTTPYFLGYMNQLRVRDYYNA-LSALHRALDRS-PVR----LMSQEKGY----QYFCVNLAVLHATFGHRDEALAALRESIMLAQEHGDKRSLNLANTWYCLLRDEL-PLSAVQKSVQDANEVDGSLLQNYTLALHFAVKLGTVAGYQPLRLFDLLQHSDNLTNRNNFADHASEALALRSAVWSAYGRHELAALYSQVLLTGR-------DRFGSGSAGLGSALASFALWLQLQGEPQLSKVLLHHAKQRFP-RLPSAEGWMISQCHVVIQAGIYQCRWHDALKACDQLYLIDPSDSLFQRASIYVAKREFFNARRLLDKLAVQDNIPFLLRMRVQVLLGYCGMANGRFSSETTMLLLRVSEEMS-EAQMDYELALVDLLLALQLLLLGMPQKAYQAIKRCMHDIHINGGLYERAKTDFVFVRCLLAVNQNDAEKRKAQLLKSQVI-LQRAAQSFKKLSAHAKVLDVYVFLAQRFNEFGDRNLRNKYAGEFRRYFTDHPIPREYLGSP-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08683-1", "uniprot_id": "APC5_YEAST", "id": "Q08683-1", "name": "Anaphase-promoting complex subunit 5", "aln": "------------------MSKYGPLGITNFITP--------------YDLCILILIHAHCS------------QDNGISVPTAVFLRLISPTRPSLEWNPLLKDNSNLRSSS-----------IVPPPVLPILDNIIRILLDDKDG---------NKIALTLMGYLEAIN--GLDSINRLMMDLEKNCLVN----------------------NYRSMKMRTTSTRRQMTRASFLGT-------------FLSTCIRKYQIGDFEMRETIWINLQNFKTVFKHTPLWLRFKDNVHIQKVKNCLLANDEISVEDQQMVEFFQHFNNGNDADSKTMNEENYG-----TLISIQHLQSIVNRQIVNWLDNTEFNLMGQEETSSTYEEQSGLVFDLLDTLSLNDATKFPLIFILKYLEAIKENSYQTALDSLHNYFDYKSTGNSQNYFHISLLSLATFHSSFNECDAAINSFEEATRIARENKDMETLNLIMIWIIN-----FIEVHPEYANRFYITVEQIIKYLKNSS--DVEDANIFSNAYKFETLLSMVKESKTAEVSSSLLKFMAITLQNVPSQNFDLFQSLVSYEVKFWKELGYESISDVYEK-FLSKTSSSSLRNYDSSIINQDIKVAFKALEEDDFLKVKQYLLKSESLELDYDQKINLKYLRVKYLVKIGDYDLSMRLINQYVKECCEEVADSNWRFKFEIESINVLLLSDVGIRSLPKIIKLIDEYKEIGNPLRCVILLLKLCEVLIQVGKSMEAECLISCNLSTILEFPFVRKKTDELLESLSVEEDRDVQMT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : * :.: :* *: :.: * . : . : : . . : : .: . . :.: : . . .: .: : : . . . . : . :. : : * :: * : .:: .:. : * * ..* : . ::: ::.* :.: *:. ..: * :.** . : . * : . . : : . : .: : : : . : :: . . : : :: : .. : :* .: .: : : : . : : : : : : : : : . . : : :. : : : :. : .:: . : *.: . . . . . .: : . :. : . : * . : . :: . . :. . . . ", "identical_positions": 18, "similar_positions": 169, "identity": "2.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1577", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JWD0-1", "uniprot_id": "A0A0G2JWD0_RAT", "id": "A0A0G2JWD0-1", "name": "", "aln": "----------------------------------MALVFSVLLLLGLCGKMASGGQPAFDNT-PGALNYEL------------------------PTTEYETQDTF----NAGIIDPLYQMVHIFLNVVQPNDFPQDLVKKLIQ-KRFDISVDTKEPENIVLALKVAIYEIGVLICVILGLLFIFLMPLVGFFFCMCRCCNKCGGEMHQRQKQNESCRRKCLAISLLLICLLMSLGIAFGFVANQQTRTRIQRTQK----LAESNYRDLRALLTEAPKQIDYILGQYNTTKNKAFSDLDSIDSVLGGRIKGQLKPKVTPVLEEIKAMATAIRQTKDALQNMSSSLKSLRDASTQLSTNLTSVRNSIENSLNSNDCASDPASKICDSLRPQLSNLGSNHNGSQLPSVDRELNTVNDVDRTDLESLVKRGYMSIDEIPNMIQNQTGDVIKDVKKTLDSVSSKVKNMSQSIP--VEEVLLQFS-----HYLNDSNRYIHESLPRVEEYDSYWWLGGLIVCFLLTLIVTFFYLGLLCGVFGYDKRATPTRRGCVSNTGGIFLMAGVGFSFLFCWILMILVVLTFVVGANVEKLLCEPYENKKLLQVLDTPYLLNDQWQFYLSGILLKNPDINMTFEQVYRDCKRGRGVYATFQLENVFNITENFNIERLSED---IVKELEKLNVNIDSIELLDKTGRKSLEDFAQSGIDRINYSMYLQ-EAEKPPTKVDLLTFASFLETEANQLPD---GNLKQAFLMDAQNIRAIHQQHVPPVQQSLNSLKQSVWALKQTS----SKLPEEVKKVLASLDSAQHFLTSNLSSIVIGETKKFGRTIIGYFEHYLQWVLYAITEKMTSCKPMITAMDSAVNGIL--CSYVADPLNLFWFGIGKATMLLLPAVIIAIKLAKYYRRMD---------------SEDVYDDVETVPMKNLENGSNGYHKDHLYG--------------------------------------------------------VHNPVMTSPSRY------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54990-1", "uniprot_id": "PROM1_MOUSE", "id": "O54990-1", "name": "Prominin-1", "aln": "----------------------------------MALVFSALLLLGLCGKISSEGQPAFHNT-PGAMNYEL------------------------PTTKYETQDTF----NAGIVGPLYKMVHIFLSVVQPNDFPLDLIKKLIQNKKFDISVDSKEPEIIVLALKIALYEIGVLICAILGLLFIILMPLVGCFFCMCRCCNKCGGEMHQRQKQNAPCRRKCLGLSLLVICLLMSLGIIYGFVANQQTRTRIKGTQK----LAKSNFRDFQTLLTETPKQIDYVVEQYTNTKNKAFSDLDGIGSVLGGRIKDQLKPKVTPVLEEIKAMATAIKQTKDALQNMSSSLKSLQDAATQLNTNLSSVRNSIENSLSSSDCTSDPASKICDSIRPSLSSLGSSLNSSQLPSVDRELNTVTEVDKTDLESLVKRGYTTIDEIPNTIQNQTVDVIKDVKNTLDSISSNIKDMSQSIP--IEDMLLQVS-----HYLNNSNRYLNQELPKLEEYDSYWWLGGLIVCFLLTLIVTFFFLGLLCGVFGYDKHATPTRRGCVSNTGGIFLMAGVGFGFLFCWILMILVVLTFVVGANVEKLLCEPYENKKLLQVLDTPYLLKEQWQFYLSGMLFNNPDINMTFEQVYRDCKRGRGIYAAFQLENVVNVSDHFNIDQISEN---INTELENLNVNIDSIELLDNTGRKSLEDFAHSGIDTIDYSTYLK-ETEKSPTEVNLLTFASTLEAKANQLPE---GKPKQAFLLDVQNIRAIHQHLLPPVQQSLNTLRQSVWTLQQTS----NKLPEKVKKILASLDSVQHFLTNNVSLIVIGETKKFGKTILGYFEHYLHWVFYAITEKMTSCKPMATAMDSAVNGIL--CGYVADPLNLFWFGIGKATVLLLPAVIIAIKLAKYYRRMD---------------SEDVYDDVETVPMKNLEIGSNGYHKDHLYG--------------------------------------------------------VHNPVMTSPSRY------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43490-1", "uniprot_id": "PROM1_HUMAN", "id": "O43490-1", "name": "Prominin-1", "aln": "----------------------------------MALVLGSLLLLGLCGNSFSGGQPSSTDA-PKAWNYEL------------------------PATNYETQDSH----KAGPIGILFELVHIFLYVVQPRDFPEDTLRKFLQ-KAYESKIDYDKPETVILGLKIVYYEAGIILCCVLGLLFIILMPLVGYFFCMCRCCNKCGGEMHQRQKENGPFLRKCFAISLLVICIIISIGIFYGFVANHQVRTRIKRSRK----LADSNFKDLRTLLNETPEQIKYILAQYNTTKDKAFTDLNSINSVLGGGILDRLRPNIIPVLDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSSSLTSVKTSLRSSLNDPLCLVHPSSETCNSIRLSLSQLNSNPELRQLPPVDAELDNVNNVLRTDLDGLVQQGYQSLNDIPDRVQRQTTTVVAGIKRVLNSIGSDIDNVTQRLP--IQDILSAFS-----VYVNNTESYIHRNLPTLEEYDSYWWLGGLVICSLLTLIVIFYYLGLLCGVCGYDRHATPTTRGCVSNTGGVFLMVGVGLSFLFCWILMIIVVLTFVFGANVEKLICEPYTSKELFRVLDTPYLLNEDWEYYLSGKLFNKSKMKLTFEQVYSDCKKNRGTYGTLHLQNSFNISEHLNINEHTGS---ISSELESLKVNLN-IFLLGAAGRKNLQDFAACGIDRMNYDSYLA-QTGKSPAGVNLLSFAYDLEAKANSLPP---GNLRNSLKRDAQTIKTIHQQRVLPIEQSLSTLYQSVKILQRTG----NGLLERVTRILASLDFAQNFITNNTSSVIIEETKKYGRTIIGYFEHYLQWIEFSISEKVASCKPVATALDTAVDVFL--CSYIIDPLNLFWFGIGKATVFLLPALIFAVKLAKYYRRMD---------------SEDVYDDVETIPMKNMENGNNGYHKDHVYG--------------------------------------------------------IHNPVMTSPSQH------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W735-1", "uniprot_id": "PRM1A_DANRE", "id": "Q9W735-1", "name": "Prominin-1-A", "aln": "---------------------------------MLWKTALIFLCWGLTSGELQNGLSATPAA-PARRTLDFG---------------------FVPSGVYDTVAYY----EPGAIGILFNMMHAFLFVVQPNPFPEDLVISAAKDKFGAIQSEYQ---------KVIYYELGFVVCAALGLLFTVLLPLVGLLFCLCRCCDNCGGEMHQRQRKNADCLRGLLTTLLLTTTFIITAGVLCAYAANQNLSSQLKGMRR----LVKSNLKDLHTFANQTPAQIDYLISRYGTVKEQVLHDLENVGVILGGRIHEELGKEVKPALDATLSMTGTMRDTKDALENVSLTLETLQEGTVKLQANLSVVRNSLRNALNDPVCVDAPAPEICRNIRNSIPKLEIAANYSSLPDVTDQLNKVNDVLKTDLSQIVAKGIASFNDTPAMVTAQTRNIVEGVKVLLDDIGNNITSFSKMLP--VHSSLANFT-----RMISHTHSQIEDIYPQIDQMDFYRWIGCITLCCMIVLILTFNFLGLLCGILGFDRHASPTTRGCVSNTGGNFLMAGVGFSFLFSWVLMGVITALFLAGGNLEKLVCEPFQTRQLFKVLDTPYLVNSAWRNFIPGYLYNDPEMDLTAYSLYSNCKDNRGIYSALHLDRIFNISSFFNTSVYSKD---VSRKFEGLKVDLRGIILLESEGKVNLNNFSETGINEIDFAAYLE-EVNKGVTRIDLIDFANQLDAQADQLSK---GTLQTSLKGHANTIRQIHIQQVVPLEQSMSTLNQSIRLLERTS----SDLPLRVEDVLKAVDDAQNLISYNATFVINQETEKYKQNIIGYFKQYIDWIRTSLALEVATCKPLSNIVDT-VEILG--CGFLLDSMNTFWFGLGCCTLFLLPSIILSVKLAKFYRRMD---------------TEDVYDE-------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P82295-1", "uniprot_id": "PROML_DROME", "id": "P82295-1", "name": "Prominin-like protein", "aln": "MGEVAATVEPLAAVKSKSMRSRKRRQRRRRQIAYLAICGLSVAIFGFALATLIRPTTAQADADPGSWRKGYVGHGTTHEQLGQPHWPPVQYTVYRPTTNYTKAPPP----PTSAMNPIFNFTHFLYDKVLYRDEPIPEGYIVVK-NSDTLSLGPKVEENDWR--DLLAHYWMVLIWVVILVVLIIVIPFIAVCYCCFCCCRRCRQGCPPCTSKQDAQRRFCCGICLLILIIGLIFGIIIAFVTNKMIDSGFAETSE----TMKRGSEDTCTYLKDVADHVHHLMMYN--YEEMETHVLDQLTHAHRHIFLDLSDTSESNSLAEMERVLENMPEALELMRQVEKMEKDLRFYGSQLRDGVRGIKRDVNFAVAN-LCQLQMCQKFLISSNIEHIDSSQCLHFDNLPNTKEFVEGMENIVASEYYAIPQRGLSRLKKVSDKVKTQLSFVVPPMMRDLTKGRTIFREHATNVRNIVEGVLSDIH-----IKTLHSTKSFEDVY---ERFGHDRNVVSLIVCLLILLVLFILIFALLCGCFGRRRTGYG-DECCSKSTGATCLLLAILLIFCVFSFIALVGLFYFMLGMVTYQGACAPLRDQENNTLFRQLDASIDLNHYLPPSESNKEVVQPLKMSSAIKACHANQTIFDMMRQHNIYDINDLTRIKVMSHSQ-ENTDSIKVFDEDLSTVVLLTKEERDELKTAGESKLAKYHSSLYMP-SLCTQFTPMNLNALSEQLYKLSNDLEYPAYGWAKVSFWNEGLNTKAFYRNFVPKLTSLVEKMKANLKKIDELISYENHDFTNTIKILTATAINSEQFIQTRGKDYINALGGNLTNSIDQMIDDYIDMIIKEANESVGHCAPLSYIYYRGVDLI---CHRIVDPINGFWVGILLCALLFLPILFVAHRLMCLYKKIYPYLATVGAAGVVEGGSDYLYDAYSERDREHVPLANVPKKRRKAYERRREQQDYFEDASPSVSRGNRSGGDRGGGGGDGAPGSSSMRYNDMAPTHWDHEPPRYHNPPAAPPSSEYERPPPYYYPGASEQD--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A1L4AAC2-1", "uniprot_id": "A0A1L4AAC2_DROME", "id": "A0A1L4AAC2-1", "name": "Prominin-like protein", "aln": "--------------------------MELKVTMWIWVIAFRLHVVKSQTNQPLHSSSKLIDQGSLVRFRRLS-----------------------PQNRYAEPESRSNNGDADSMCPITYLSHVFTGSVVSYAKEVPKGYISKDGNDIGSKVQEDD------WEAYLASQKGLKILVLLLVLLFLLILILGLLYACCCVAWEK-------NERSSRGCRYCCGILLAILALLMLLFLILAIMAATQLNINLKNLKASGCYPSNSSQSSADYIFQKASERLRHLYVIN--YDQKVKRIKSALNQDPSIKYPNRELEVHAKAIERLIEVLRNMRRIKPVMLRIKNRLLDARRLATQFRDALRGVKRDLMVILIA-DCTHSECQDFYRANEIKMLDMG-CLHYDSLPEFEPLLESVQEVIDSKFIDYPLQAVGQLRRMSSAIKNRMSDILDSVNKDLNKGAKKLQERYEASLKVLRQVVEEMKKDMPLVVKTNPRSRSTPAADLRRKLGSSWFGTTLCLIVLLMLVPLLLLFGLLIALFS-------------PKVASWLLCAVLVALFILFSVGVILVLFYLVHGALIYQAFCSRKFPQP------VDNKSINPNKFLPENVTTFRSMPMVRTSEILQSCVRNESLYNVLGIKEIYDPYGFRDDVMIDVVKSLEKMGNTSMPGAPKEIHPDAEESAKKLLTGNLSTYDIKDYTKYICPQLVPEPNPGPLDGLTRKLESLANKVEP------GVTLKNQAIHLRAYQKHLCVPLAAIVQRLIKRLKQMDWLLSGGYGSFVKYLHHLLDKIKQGDDLLRQDSKKEADEVARNISKLVKSGLDDYVRVVEEATKEDMESCEPLIREDDEAMVEYADLCNRIAKPMNAIWFWLLLFSSLLLPTICCTHFLRSRLNSLK--------------HSVATPVSYGESNFMAPGILPLGLPQCQCYR---------------------------------------------------------YLPVSAETNVDYLEGMEDYYVDQVKRKRE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . * * .. : : : * : * . : . . . : : ::: .:: ::. :. . . .. * * : : : . : : . . . ... :: :: .: . : : : : : .:. : :: : :: .: : * . . . . . . .** :: : :: :. :. : . : : :: : * . . . . :. : . .. . . : : :: *: : :.** . . .... * : * . . : :: * : * : . . . : . * .. : : .. : : : .* . *: . * :: * ::.: :: . : : : :. : : :. : : : :.:: . : . : :..*: : .: * *: : * : ..:* :*. : : ::** : : * . : : ", "identical_positions": 31, "similar_positions": 196, "identity": "2.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-158", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQG0-1", "uniprot_id": "D3ZQG0_RAT", "id": "D3ZQG0-1", "name": "", "aln": "MAAPAKGMWYSLGPLLRVVQTR--DLDARRWVRALRRSP--VRVLFPS-------GQVEERKRAPDKQPRKAVPEASSQ---GQQQKQPLETSPSQ-------TPHT--WEEAGLRYDKACPGDRRLS-VMTIVKSRPFREKQGKILLEGRRLIADALKAGAVPKMFFFSRLEYIKELPVDK-----LKGVSLIKVKFEDIKDWSDLVTPQGIMGIFAKPD----PVKMTYPETQLHHSLPLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFQVPIVNNVEWETVPNHLPPDTRVYVADNCGLYAQVQMSNKTGDRD-WACDRRFLKFHKN--EVDLDTKAR-----KDWLP----KLEVQSYDLDWTEAPAALVIGGETHGVSLESLQLAESTGGKR--LLIPVVPGVDSLNSAMAASILLFEGKRQLRIKMGDLSRDSCCH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5ND52-1", "uniprot_id": "MRM3_MOUSE", "id": "Q5ND52-1", "name": "rRNA methyltransferase 3, mitochondrial", "aln": "MAAPAKGMWCSLGSLLRVVQTR--DLNARRWVRALRRSP--VRVLSPS-------GQVEERKRAPDQQPRKAVPKASSQ---GQRQKQPLETSPSQ-------TPHT--WEEAGLRYDKAFPGDRRLSSVMTIVKSRPFREKQGKILLEGRRLIADALKAGAVPKAFFFSRLEYVKELPVDK-----LKDVSLIKVKFEDIKDWSDLVTPQGIMGIFAKPD----PVKMTYPETPLHHTLPLVLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFQVPIVNNVEWETVPNHLPPDTRVYVADNCGHYAQVQMSDKTGDRD-WACDRRFLKFHKY--EEDLDTKTR-----KDWLP----KLEVQSYDLDWTGAPAAVVIGGETHGVSLESLQLAESTGGKR--LLIPVVPGVDSLNSAMAASILLFEGKRQLRIKVEDLSRDRSYH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HC36-1", "uniprot_id": "MRM3_HUMAN", "id": "Q9HC36-1", "name": "rRNA methyltransferase 3, mitochondrial", "aln": "MAALVRPARFVVRPLLQVVQAW--DLDARRWVRALRRSP--VKVVFPS-------GEVVEQKRAPGKQPRKAPSEASAQ---EQREKQPLEESASR-------APST--WEESGLRYDKAYPGDRRLSSVMTIVKSRPFREKQGKILLEGRRLISDALKAGAVPKMFFFSRLEYLKELPVDK-----LKGVSLIKVKFEDIKDWSDLVTPQGIMGIFAKPD----HVKMTYPKTQLQHSLPLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIINNLEWETVPNYLPPDTRVYVADNCGLYAQAEMSNKASDHG-WVCDQRVMKFHKYEEEEDVETGAS-----QDWLP----HVEVQSYDSDWTEAPAAVVIGGETYGVSLESLQLAESTGGKR--LLIPVVPGVDSLNSAMAASILLFEGKRQLRGRAEDLSRDRSYH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L2E4-1", "uniprot_id": "MRM3B_DANRE", "id": "A1L2E4-1", "name": "rRNA methyltransferase 3B, mitochondrial", "aln": "MATRIASMRFRCALFQSALTLGRNEVNIKRYVRRRRAVSGVVSVNEPTEISEGVISQTSERSSQHNNDITRNTDKSSIENPVSPNNSQPVQFSHINRQKVINLTSRTRFGEVDGLLYEKLHPGDKSLAKLARIAGSKKLREHQ--VVLEGKHLVCSALDAGAEAQTLYFSSVDALRELPLDK-----LRQTNVVKVKMEDAQVWSELDTSQEIIAIFKRPE----ASRLTFSEEKYGRAVPLTLICDTVRDPGNLGSVLRSAAAAGCHSVLLTKGCVDIWELKVLRAAMGAHFRLPIIPNLTWTDISNHLPKTSTVHVADNHSTTMGKHNDNTTPQKHRRPSDYGWVKGHQYQSKAHDDDDANDLCSLEDYCDENSKSLETQLYYTDWVAGHTSLIIGGETHGLSREALQLAERTSGRR--LLIPMVDGVDSLNSAIAAGVLLFEGRKQL------LSLEKIRV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VW14-1", "uniprot_id": "MRM3_DROME", "id": "Q9VW14-1", "name": "rRNA methyltransferase 3, mitochondrial", "aln": "MLCNIFKRSLQAN-IRNVNNLNVLRLSSSSGPRGEIQDALDIEANLFGN-SDLRHEPMNTREALRKNRFAGRKPKVPFASVASRNLSAPSNPAPRVAP----TPAPVIKDNELNLEFVRLTLQDPLTSTLLTTVRSRKRRDKNRQIIVEGRRLIQEALQCGLKMEVLLFSQKDQLALVKEEVGVAQVETGTKIYKVPQHDLKTWSSLVTPPGLMAIFDRPSDKGLEKNLAEQQRLGSQPFPITVVCDNIREPNNLGSIIRTCAALPCSQVVVTHGCCDPWESKALRGGCGGQFRVPIRDDVTWDELALTIPPEA----ADDCHVFIAETNQRKRENNQ-----------------------------------------TIDYADIKGLGAHNLLIIGGESHGVSEEAYRFLNLVGGKGKCIYIPLAAGIDSLNVASALTLLLFELRRKLIHQASEKE------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . :. * . : . :. : : . . . * : : .. . : .* : : * : : . *: *::: :::**::*: .**..* : : ** : : : : ..: ** .* : **.* *. ::.** :*. .:: : :..*: ::**.:*:*.***:::*:.*. * .*::*:** * ** *.**.. *.:*::** :: * :. :* : **: . . :. : . . ::****::*:* *: :: : ..*: : **:. *:**** * * :**** :::* . ", "identical_positions": 76, "similar_positions": 123, "identity": "16.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1582", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2APC3-1", "uniprot_id": "TTLL9_MOUSE", "id": "A2APC3-1", "name": "Probable tubulin polyglutamylase TTLL9", "aln": "------------------MSRQKNQNSKGHGVSKGKEREQRTLIRFKTTLMNTLMDVLRHRPGWVEVKDEGEWDFYWCDVSWLRENFDHTYMDEHVRISHFRNHYELTRKNYMVKNLKRFRKYLERESGKTEAAKCDFFPKTFEMPCEYHLFVEEFRKNPGITWIMKPVARSQGKGIFLFRRLKDIMDWRKGTSGKKPTGVETQPARANMNPSGSHDTRSSDDQKDDLPVENYVAQRYVENPYLIGGRKFDLRVYVLVMSYIPLRAWLYRDGFARFSNTRFTLNSIDDHYVHLTNVAVQKTSPDYHLKKGCKWMLQRFRQYLASKHGPKAVETLFSDMDNIFIKSLQSVQKVIISDKHCFELYGYDILIDQDLKPWLLEVNASPSLTASSQEDYELKTCLLEDTLHVVDMEARLTGKEKRVGGFDLMWNDGPVSREDGPSDLSGMGNFVTNTHLGCVNDRKEQLRQLFRSLQAQRKAPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3SXZ7-1", "uniprot_id": "TTLL9_HUMAN", "id": "Q3SXZ7-1", "name": "Probable tubulin polyglutamylase TTLL9", "aln": "MVPSREALLGPGTTAIRCPKKLQNQNYKGHGLSKGKEREQRASIRFKTTLMNTLMDVLRHRPGWVEVKDEGEWDFYWCDVSWLRENFDHTYMDEHVRISHFRNHYELTRKNYMVKNLKRFRKQLEREAGKLEAAKCDFFPKTFEMPCEYHLFVEEFRKNPGITWIMKPVARSQGKGIFLFRRLKDIVDWRK-------------------------DTRSSDDQKDDIPVENYVAQRYIENPYLIGGRKFDLRVYVLVMS--VFAECLLWSGHRRQD-------------VHLTNVAVQKTSPDYHPKKGCKWTLQRFRQYLASKHGPEAVETLFRDIDNIFVKSLQSVQKVIISDKHCFELYGYDILIDQDLKPWLLEVNASPSLTASSQEDYELKTCLLEDTLHVVDMEARLTGREKRVGGFDLMWNDGPVSREEGAPDLSGMGNFVTNTHLGCVNDRKKQLRQLFCSLQVQKKASS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QT18-1", "uniprot_id": "F1QT18_DANRE", "id": "F1QT18-1", "name": "Tubulin--tyrosine ligase-like protein 9", "aln": "----------------MSKNKQTTGHKAAHSSQRKKEVEARSCIRYRCGLTNTIQDVLNHRPGWVEVKDDAEWDFNWCDVGWLRENFDHSYMEEHVRICHFRNHYELTRKNLMVKNLKRYRKTLEREVGRLEAAKCDFFPRTFELPSEYHIFVEEFKKSPGNTWIMKPVARSQGKGIFLFRKLKDIIDWRK-------------------------DGSRSEEQKDEAQVESYVAQRYIENPYLIAGRKFDLRVYVLVTSYIPLKAWLYRDGFARFSNTRFSLSSIDDQYVHLTNVAVQKTAPDYDPEKGCKWQMQQLRWYLTAKHGFETVQTLFKEIDNVFIRSLLSVQKTIINDKHCFELYGYDILLDQDLKPWLIEVNASPSLTASSQEDYDLKYRLLEDTLHIVDMEGRLTGKEKRIGGFDLMWNDGPVYTDVGLEALG-SSCLVANTHLGCVNDREKQLQQLLKPFPGQKKT--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . : .*. .: ** * *: **:: * **: ***.**********:.**** ****.********:**:*****.************ *******:** **** *: *********:***:*.***:*****:*.** *******************:****:**** * *::***: **.******:******.************ * : * .*. * . ***********:***. :***** :*::* **::*** ::*:*** ::**:*::** ****.**.*************:********:****************:** *******:****.****:***:************ : * *. . :*:**********::**:**: .: *:*: ", "identical_positions": 287, "similar_positions": 77, "identity": "59.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1599", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K2B0-1", "uniprot_id": "SC65_MOUSE", "id": "Q8K2B0-1", "name": "Endoplasmic reticulum protein SC65", "aln": "-MARGAWGLLWLLLGSAG----AQYEKYSFRGFPPEDLMPLATAYGHALEQYEGESWRESARYLEAALRLHRLLRDSEAFCHANCSGPATSQPRPASGPDGDHDGDGEDWARELRLFGHVLERAACLRRCKKTLPAFQVPYPPRQLLRDFQSRLPYQYLHYAHFKANRLEKAVAAAYTFLQRNPKHELTAKYLNYYRGMLDIGDESLTDLEAQPYEAVFLRAVKLYNSGDFRSSTEDMERALAEYMTVFARCLAGCEGAHEQVDFKDFYPAIADLFAESLQCKVDCETNLTPNVGGFFVDKFVATMYHYLQFAYYKLNDVRQAARSAASYMLFDPKDSVMQQNLVYYRFHRARWGLEDEDFQPREEAMLYHNQTSELRELLDFTHMYLQSDDEMELEETESLPEPEEPLSDAEFEGEGDYEEGLYADWWQEPEAKGDEAEAEPEPELT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92791-1", "uniprot_id": "SC65_HUMAN", "id": "Q92791-1", "name": "Endoplasmic reticulum protein SC65", "aln": "-MARVAWGLLWLLLGSAG----AQYEKYSFRGFPPEDLMPLAAAYGHALEQYEGESWRESARYLEAALRLHRLLRDSEAFCHANCSG-----PAPAAKPDPDG-GRADEWACELRLFGRVLERAACLRRCKRTLPAFQVPYPPRQLLRDFQSRLPYQYLHYALFKANRLEKAVAAAYTFLQRNPKHELTAKYLNYYQGMLDVADESLTDLEAQPYEAVFLRAVKLYNSGDFRSSTEDMERALSEYLAVFARCLAGCEGAHEQVDFKDFYPAIADLFAESLQCKVDCEANLTPNVGGYFVDKFVATMYHYLQFAYYKLNDVRQAARSAASYMLFDPKDSVMQQNLVYYRFHRARWGLEEEDFQPREEAMLYHNQTAELRELLEFTHMYLQSDDEMELEETEPPLEPEDALSDAEFEGEGDYEEGMYADWWQEPDAKGDEAEAEPEPELA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4INE3-1", "uniprot_id": "A0A0R4INE3_DANRE", "id": "A0A0R4INE3-1", "name": "", "aln": "MVDTKTYFFVFLSIAYSSSFVKAQYEKYSFKSFPMNDLMPLESAYGHALEMYATQDWKQSLTYLELSLRLHRLLRDSEAFCSSNCST-------VCSEYENNS------TGTTFRIMEHIILRAACLKRCKTKFPVFSKSYPKRETLAAFEKRIPYRYLQFVYYQMNELERAVSAAHTYLQRNPGDPLLSRSVNYYKSLFDL-EEYLIDHEEKSYEALFLKAVKLYNSGDFSSSVRDMELTAAEYFTKYQMCLLSCEGSYDVQEFKDFYPALAELYFEVLQCKVKCEENLMPNVGGYFVDKFVATMFHYMQFAYFKLNDVRNAALCAATYMLFDRDDQVMQQNMAYYRFYREQWGLQDEHFKPRPEALKYYNLITKLRELLEFANNYLQTDDEDSVSADEAVLSNP---ADEEFEGIGDYEESFLAEWWQEPKTKGDTGEPVE-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :::* :. :. ********:.** :***** :******* * :.*::* *** :************** :*** .: : : . :*:: ::: *****:*** .:*.*. .** *: * *:.*:**:**::. :: *.**:**:**:*:***** . * :: :***:.::*: :* * * * :.***:**:********** **..*** : :**:: : ** .***::: :*******:*:*: * *****.** ** *****:*********:**:****:******:** .**:***** .*.*****:.****:* :***::*.*:** **: *:* ::*****:*:: ***:*** .:. *. . :* **** *****.: *:*****.:*** .*. ", "identical_positions": 225, "similar_positions": 120, "identity": "50.22%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1613", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VQN3-1", "uniprot_id": "Q9VQN3_DROME", "id": "Q9VQN3-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLINLKSKDMYDEPIN-----------------------------------LWRTKQRVHYHHDVIS------------------------------KGNDSHRSSDACEYITISAPKKSGS-------------------FSRSPPSSLPTSVPGTPRHS----------------VAATSNQV-IRYARTSCDHCGHHSIPVMSPHPISPLAKSQTNLDLVEHGSQRQALLPLPTVGMHHEDSACTLQVS---------------------------------RRPSLLLQEILTQRPPLFGRRDGNGFLSPRTAKNGNLQGTASGS--------TATINFQSGATSARNGSTAFFDNGAKSFQAKQ-----------------QKDKNRRTG--------------------------------------------------------------------NDAISSALSATYC--KLLVLLGVCLPITEVIS-DQIPTYVYQGFYVYLYVGSILFVIFLYISAFRNR-----------------SLFNALKDYHEKNSNVH-----------------LKHKVTHFGSFYLRVGAIAFAIGTMVYSGLEFGQFFELNGHPGCRDVFVAITPICRMVLCIAQVQFIFLNTTYMDMARHKVTSRFGLMHMVATNLCEWLYVLVEETKHEIFHISQHEVDPAHDLVIHNSSMSRTDWAAVNESLHQHHHH-------HALNNTLVANVSSVIVNMTITPSPTPAAFSGCSRTTIMGALVQQLSPFLFPCTIEYSLICAVILFEMWKTVKS-----IPDIDKTRKNSVK----PAAAKPAHHFSVDCSQSHKGLFFGILIIVMTIISMIMYFVLYTQPGYELVATQEVTLWETFMYFMCAAAVITGMILMRDLRYIKNTSDEHHSMDLDNLLLIVAQTGVYLYGMFSILGSYFAKWDTVPDRVEG------IIAEVFGVVQTSLQTMF---------ILHSSHRRCRGTNQVRRKPGREIITFLLVANIAIWFVNTLIKGRAVFRESHLEFFGVWGWTIITHISMPLAIFYRFHSTICLFEVWKITYKAKAH---------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B7Z0W9-1", "uniprot_id": "OTOP_DROME", "id": "B7Z0W9-1", "name": "Proton channel OtopLc", "aln": "MDSSPDLSLKLRRGSSDSRDNFYMDFAQGIDSDIEEVDNTANNQEAGEVPPPPLPTVSLAEEVLLLVAPPPPPPSLLGQPLPTLTETDDIPPTPTPPPQQKDDEGDDEDEREEPVPEQDQGAPAAPSPPGSPINSVLELELIPPPPLSPMDDAGLRTDDDGEGEETDDAEEVAAIPPPHEMLDIESNPDEEEEEEEQEQASQEDTPKEEDEEEDDDKSTPPPPLPPLPSNFSYVQGHNLGQVTPPLTKSPSNSPSPPVTPPPCPELNISRMVSPPAQHISQIPPLTPSDESEGEAESQPNSPPLRLDAEQPPPDMDQPEPEDQPPEPENEPEPEPEPEPEPEPVSGAREDYSRSLDNEDESTTITTPPSNGYSASSIIAPPPEHFAELDEDRGFIPPPPLEQEPEEEVEEEEEEEEEELTKETDEISVDRESLQDQGGDSISSPRPASILTGSISTSVGGGAGGSPKPESRGPSRSGSQRSQLRSGSQQGSIAESRGGSRIGSRTGSVASAQAAGVLSPQASLKSQTSIRSQGQAGVRSPAGSIKSGSQRMQSPQAGEGAPAMPSPPLMRSPPPELARQMHSPPRITTPPRVCSPPLVSSPPKLAESAAAA-VGVAATVKEQIGSSSSTAEPLEPSKPEPLKPPIATVSYQDEQKPSPPPTAAAAPAVTTTAATTAVTSQPRSHFTSSHHHYHLPHQFQHPHHQNHHTHSVRVPTPTVPSSYAPPPPPDSGSSSSPVDRRRLFMAGVAPPIAAGAGSLMAMPAEPAVAISPGRVSARSGSQHHVTIDESSLPSHKGNIQETPGPSGLIIGGGDGDGDRDIGGGGGPDSSDPPSSPGGSSSQPALSGSQADGQLALMYHSHQLTNYPVLPAIKRTHRPSFVYPPMPRVKAGDALATLFSALYG--KLLVVMGIAFPMAEVIS-TYIPPSFYEVYYLYLYIGSMIFLLFMYATLIWGRPKLPVPIASPSKSATKASGTDSMDESDTDSNSVHHRLPPPIPVRRPSLLSPLGRRDAHYGSFYLRMGAVAFGIGSMIYSGLEFGQYFELNPDTKCHNVLLALTPATRMAFIFIQMYFIFLNNEQIKVYRYKIIARFGLMHMIGTNLAVWLNVLIQETKHEILTFYNPENR---TLRISHRIPGHSRGHAIIQ--HDPTAH-------LRVPRGLKG----------------PYQIFECRRTNIIGTLVQDASPFLFPCTIEYSLICAAILYVMWRSISR-----PQTPTPQRPDMIS----SPMKRSPHHYSVDCARAHKGLFVGILILVLTIISLIIFFVLISRPEFVAMAVTEVTICELLIYGTATIATLVGMIQIRHLQY-----DAYRSFSLDDILLVGAQTGSFLYNIFTVIAGHFTLRS---DDMLV------PINALASIVQTACQTMF---------ILDASRRQAVSPEHLRKKPGREIVTFMLVVNLAMWAISTLEKSRAESHPIQLNFYGLWAWTIITHVSMPLAIFYRFHSTVCLCEIWKRAYKLKPTYMXEFARSRIQSIAQQQQFCEDLKTNLSYCYCSTTLAGGELETVEEVDSGESNSAEDAGAGAGSGGSRGSGGGAGAAEAGEAGEEGQQGGDSSCGLKAPIRALSPQSLNTEKAFCPVYVINGE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7M734-1", "uniprot_id": "OTOP1_RAT", "id": "Q7M734-1", "name": "Proton channel OTOP1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGDRGALSSPAASS--------GSPSAAPSGIAACPPPPSPLARASPQASGPRRG------------------------------------------------------------------------------------------ASVPQKLAETLSSQYG--LNVFVAGLLFLLAWAVHATGVGKSDLLCVLTALMLLQLLWMLWYVGRSYMQR-------------------------------------------------RLIRPKDTHAGARWLRGSITLFAFITIVLGCLKVAYFIGFS---ECLSATEGVFPVTHAVHTLLQVYFLWGHAKDIIMS-FKTLERFGVIHSVFTNLLLWANSVLNESKHQLNEHKERLITLGFGNITIVLDDHTPQCNCTPPALCSALSHGIYYLYPFNIEYQILASTMLYVLWKNIGRRVDSSRHQKMQCR-FDGVLVGSVLGLTVLAATIAVVVVYMIHIGRSKSKSESALIMFYLYAITVLLLMG----AAGLVGSWIYRVDEKSLDESKNPARKLDADLLVATASGSWLLSWGSILAIACAETR--PPYTWYNLPYSVLVIVEKYVQNIFIIESVHLEPEGVPEDVRTLRVVT-VCSGEAAALAASSLGSQGTAQDGSP-------AVNGNLHLQQRCEKEDQ---EADWEGATGTTRCLDFLQGGMKRRLLRNITAFLFLCNISLWIPPAFGCRPEYDNGLEEIVFGFEPWIIVVNLAMPFSIFYRMHAAAALFEVYCKI---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80VM9-1", "uniprot_id": "OTOP1_MOUSE", "id": "Q80VM9-1", "name": "Proton channel OTOP1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGGPGAPSSPAASS--------GSSRAAPSGIAACPLSPPPLARGSPQASGPRRG------------------------------------------------------------------------------------------ASVPQKLAETLSSQYG--LNVFVAGLLFLLAWAVHATGVGKSDLLCVLTALMLLQLLWMLWYVGRSYMQR-------------------------------------------------RLIRPKDTHAGARWLRGSITLFAFITVVLGCLKVAYFIGFS---ECLSATEGVFPVTHAVHTLLQVYFLWGHAKDIIMS-FKTLERFGVIHSVFTNLLLWANSVLNESKHQLNEHKERLITLGFGNITIVLDDHTPQCNCTPPALCSALSHGIYYLYPFNIEYQILASTMLYVLWKNIGRRVDSSQHQKMQCR-FDGVLVGSVLGLTVLAATIAVVVVYMIHIGRSKSKSESALIMFYLYAITVLLLMG----AAGLVGSWIYRVDEKSLDESKNPARKLDVDLLVATGSGSWLLSWGSILAIACAETR--PPYTWYNLPYSVLVIVEKYVQNIFIIESVHLEPEGVPEDVRTLRVVT-VCSSEAAALAASTLGSQGMAQDGSP-------AVNGNLCLQQRCGKEDQ---ESGWEGATGTTRCLDFLQGGMKRRLLRNITAFLFLCNISLWIPPAFGCRPEYDNGLEEIVFGFEPWIIVVNLAMPFSIFYRMHAAAALFEVYCKI---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7RTM1-1", "uniprot_id": "OTOP1_HUMAN", "id": "Q7RTM1-1", "name": "Proton channel OTOP1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLEGLGSPASPRAAA--------SASVAGSSGPAACSPPSSSAPR-SPESPAPRRGGV---------------------------------------------------------------------------------------RASVPQKLAEMLSSQYG--LIVFVAGLLLLLAWAVHAAGVSKSDLLCFLTALMLLQLLWMLWYVGRSSAHR-------------------------------------------------RLFRLKDTHAGAGWLRGSITLFAVITVILGCLKIGYFIGFS---ECLSATEGVFPVTHSVHTLLQVYFLWGHAKDIIQS-FKTLERFGVIHSVFTNLLLWANGVLNESKHQLNEHKERLITLGFGNITTVLDDHTPQCNCTPPTLCTAISHGIYYLYPFNIEYQILASTMLYVLWKNIGRKVDSHQHQKMQFK-SDGVMVGAVLGLTVLAATIAVVVVYLIHIGRSKTKSESALIMFYLYAITLLMLMG----AAGLAGIRIYRIDEKSLDESKNPARKLDSDLLVGTASGSWLISWGSILAILCAEGH--PRYTWYNLPYSILAIVEKYIQNLFIFESIHREPEKLSEDIQTLRVVT-VCNGNTMPLASSCPKSGGVARDVAPQGKDMPPAANGNVCMRESHDKEEEKQEESSWGGSPSPVRLPRFLQGNAKRKVLRNIAAFLFLCNISLWIPPAFGCRPEYDNGLEEIVFGFEPWIIVVNLAMPFSIFYRMHAAASLFEVYCKI---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZWK8-1", "uniprot_id": "OTOP1_DANRE", "id": "Q7ZWK8-1", "name": "Proton channel OTOP1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVEHGGTDSMWLNK--------YNPAAASSASSSSSSDAENKLFSRLKVSLTKKY---------------------------------------------------------------------------------------------PQKNAELLSAQYG--TNLLLLGVSVMLALAAQSGPVKEEHLLSFITVLMLVQLVWMLCYMIRRERER-------------------------------------------------SPVPERDAHAGASWIRGGLTMLALLSLIMDAFRIGYFVGYH---SCISAALGVYPIVHALHTISQVHFLWFHIKDVIKK-YETFERFGVIHAVFTNLLLWCNGVMSETEHFMHNHRRRLIEMGYANLSTV--DVQPHCNCTT-SVCSMFSTSLYYLYPFNIEYHIFVSAMLFVMWKNIGRTLDRHSNRKRRSTGSTGLLLGPLGGLVALASSVSVLVVYLIHLEKTEEMHEAAVSMFYYYGVAMMACMC----VGSGTGLLVYRMENRPMDTGSNPARTLDTELLLASSLGSWLMSWCSVVASVAEAGQKSPSFSWTSLTYSLLLVLEKCIQNLFIVESLYRRHSEEEEDAAAPQVFS-VAVPPYDGILNHGYEAHDKHREAEP--------AAGSHALSRKQP-----------DAPLPAGQRLDVTPG-RKRQILKNICMFLFMCNISLWILPAFGCRPQYDNPLENETFGTSVWTTVLNVAIPLNLFYRMHSVASLFEVFRKV---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1JJE6-1", "uniprot_id": "E1JJE6_DROME", "id": "E1JJE6-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQRCPYIHEMRERLLDQPRETLQLENMERANLLDNRQSASESNQLQGDGYHTSPAHQRTPLVPHDLGEDFN---LDFDDDFPIDARRPKNAKVCYTFKPNPNKYSFMPAKITVQGTYETNPITGPIELWTSLFIVTSLVYAILLIVVCIAYVISDVTTHRLPVLYYETFFTYLYGVSILFLLYVFCFLLQESSCCNGGNGGSKPKPQPKEKKSKKAKNADPADSKDAKGSKDSGKAAKGAAYQHTLAKFLEAPVDAEVAVTPKNVRKRKTTHSDLTHGSFFLRVGAIAFGLGAMIYIGLEFGSFFEIPFDSPCHHILIGVNPLLQMIFTFMQMYFIFMNARLNIHRFKVIAR----------------------------------------FGLMHVVATNICVWIRTLVKESLLEITIYHQKNEPEAGASSIAHSIRQHALRHAGTVLRTHAGPNSEFEVLDGEDILPKDVYKS-------------------------------------------------------------------------------------------DNVLSKLVRNTVDGISKSLGMGGDQALDSSTTSSSTTTTTRAPFTTPNYQWHSTTMARKLKKFITSATTAAT--------------------------------------------TAAGSSSTASSTTTISPTISSTTIPSTTISSTTISSSTTFSPFSPSTTTTTTTTAAALNLETSGSESPFGGLQRILSSAAPPSLAPVDGFGSASAATPTSGSGAGSFVDSFLASTLSPASSTEGSASIMNNLFGQGPMENSFQTYTDLGHEEATGLVSFENLESLDN-----IYPAALSSNIGTLNSTACGRIDIMGTIVYDSAPYLYPFIIEYSLIGAVVLYVMWKHIGRYPGRMNDEDLEHRLEVMLSRRAVAMAQQARSGRVDCVGSSKGLFFGLLLLVGALICLILFFVLVRHQQFSLLAIYLADASHCILMAFAILAIIVGFIRVKNLKFR-----CEEQSNLNDILLRISAFGLFTYSVFSIIAGSLKVLESEPSLLVT-------TTGGVAVFQVILQLLF---------IADVSRRRVHLPEHDRSKPGRQIVTFLLICNVAMFAIYTFEAQKVFANPVQLEFYGFVPWSIIQRITLPLCIFHRFHSAVTLAEIWKTTYKARLE---------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : : . . * : : : .: : . : . .. . . . . : : .. : : . . : : * :: :: : . : :: . . : :: * : : . . : . :: : . : . : : : ::* *::: *:::: :: . . :* * : .:::*: :*:*:*:. * *:: ", "identical_positions": 14, "similar_positions": 88, "identity": "0.85%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1620", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7M0-1", "uniprot_id": "D4A7M0_RAT", "id": "D4A7M0-1", "name": "Plexin-C1", "aln": "MEVSRRKAPPRPPYPAAPLPLIAYLLALAVPARGADEPVWRSEQAIGAIAASRADGVFVASGSCLDQLDYSLKNRLSRLYRDQAGNCTEPVSLAPPARPRPGSSFSKLLLPYREGATGLEGLLLTGWTFDRGACEVRPLGNLNRSSLRNGTEVVSCHPQGSTAGVVYRASGTDLWYLAVAATYVLPEPETANRCNPAASDRDTAIALKNTEGRSLATQELGRLKLRGSAGSLHFVDAFLWNGSVYFPYYP-YNYTSGAATGWPSMARIAQSTEVLFQGQAALDCGHGHPEGRRLLLSSSLV--EAVDIWAGVFSAATGEGQEKRSPATTALCLFRMSEIQARARSCSWDFQATEHNCKEGDQPEQVQPIASSTLIHSDLTSVYGTVVMNRIVLFLGTGDGQLLKVVLGENLTSNCPEVIYEIKEETPVFYKLVPHPVKDTYIYLTAGKEVRRIQVANCSKRKSCFQCLAAADPHCGWCLPLQRSSFMGGGDAVRHFLNWRSMAEGPHHTPKSQWSKALKERTTVTIVGSVSARHS-----ECVVKNADTGKLLCQGRSQMNRTCACNIPSRPSN-NVFVVNATFTFPSWSVSERFNFTNCASVR---------ECPACIETGCAWCKRDKRCIHPFTPCEPSDYERNQELCHVAVEKPPKDSGGGRVKESKRNRTDPALQVFYIKAIEPQKISTLGKSNVIVTGANFTQASNITMILRGTSTCEKDVIRVSHVLNDTHMKFSLPSSRKEMKDVCIQFDGGNCSSAGALSYIALPHCSLIVPATTWISGGQNITIMGRNFDVIDNLIISHELKGNINVSINVSEYCMATSCRFLAPNLKSSKGRTNVVVKLRVQDTYLDCGTLQYLEDPRFTGYRVESEIDTELEVKIQKENDNFNISRDDIDITLFHGENKQFNCSFENITRNQDLTTILCKIKSIKNANTIATSSKKVRVKLGNLELYVEQESVPSTWYFLIALPILLAIVIVVAVVVTRHKSKELSRKQSQQLELLESELRKEIRDGFAELQMDKLDVVDSFGTVPFLDYKHFALRTFFPESGGFTHIFTEDMHN-RDANDKNESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYLTSILEVLTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFNTVALNVVFEKIPENESADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLELQVGTRQKELLDIDSSSVILEDGITKLNTIGHYEISNGSTIKVFK--------KIANFTSDVEYSDDHCHLILPDSEAFQVVQGKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPNSRAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVF-DIKKTPHIDSCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRDLPPLSSLEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQLLHVKVLFDEKKKCKWM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZC2-1", "uniprot_id": "PLXC1_MOUSE", "id": "Q9QZC2-1", "name": "Plexin-C1", "aln": "MEVSRRKTPPRPPYPAAPLPLIAYLLALAAPARGADEPVWRSEQAIGAIAASRADGVFVASGSCLDQLDYSLKNRLSRLYRDQAGNCTEPVSLAPPARPRPGSSFSKLLLPYREGATGLEGLLLTGWTFDRGACEVRPLGNLNRSSLRNGTEVVSCHPQGSTAGVVYRASGTDLWYLAVAATYVLPEPETANRCNPAASDRDTAIALKNTEGRSLATQELGRLKLRGSAGSLHFVDAFLWNGSVYFPYYP-YNYTSGAATGWPSMARIAQSTEVLFQGQAALDCDHGHPEGRRLLLSSSLV--EAVDIWAGVFSAATGEGQERRSPATTALCLFRMSEIQAHARSCSWDFQATEHNCKEGDRPERVQPIASSTLIHSDLTSVYGTVVMNRTVLFLGTGDGQLLKVVLGENLTSNCPEVIYEIKEETPVFYKLVPHPMKNIYIYLTAGKEVRRIPVANCSKRKSCSECLAAADPHCGWCLPLQRCTFQGDCTHAGSFENWLDISSGPKKCPKIQILRSLRERTTVTIVGSISARHS-----ECVVKNADTGKLLCQGRSQLNWTCACNIPSRPSY-NVLVVNATFSFPSWNLSERFNFTNCASLK---------ECPACIRSGCAWCKRDKKCIHPFTPCEPSDYERNQELCQVAVEKSPKDSGGGRVKESKRNRTDGAVQVFYIKAIEPQKISTLGKSNVIVTGANFTQASNITMILRGTSTCERDVIRVSHVLNDTHMKFSLPSSRKEMKDVCIQFDGGTCSSAGALSYIALPHCSLIVPATTWISGGQNITIMGRNFDVIDNLIISHELKGNANVNINVSEYCAATFCRFLAPNLKSSKVRTNVAVKLRVQDTYLDCGTLQYLEDPRFTGYRVESEIDTELEVKIQKENDNFNISKDDIDITLFHGENKQFNCSFENITRNQDLTTILCKIKSIKNANTIASSSKKVRVKLGNLELYVEQESVPSTWYFLIALPILLAIVIVVAVVVTRYKSKELSRKQSQQLELLESELRKEIRDGFAELQMDKLDVVDSFGTVPFLDYKHFALRTFFPESGGFTHIFTEDMHN-RDANDKNESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYLTSILEVLTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFNTVALNVVFEKIPENESADVCRNISVNVLDCDTIGQAKEKVFQAFLSKNGSPYGLQLNEIGLELQVGTRQKELLDIDSSSVILEDGITKLNTIGHYEISNGSTIKVFK--------KIANFTSDVEYSDDHCHLILPDSEAFQVVQGKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPNSRAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVF-DIKKTPHIDSCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRDLPPLSSLEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQLLHVKVLFDEKKKCKWM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60486-1", "uniprot_id": "PLXC1_HUMAN", "id": "O60486-1", "name": "Plexin-C1", "aln": "MEVSRRKAPPRPPRPAAPLPLLAYLLALAAPGRGADEPVWRSEQAIGAIAASQEDGVFVASGSCLDQLDYSLEHSLSRLYRDQAGNCTEPVSLAPPARPRPGSSFSKLLLPYREGAAGLGGLLLTGWTFDRGACEVRPLGNLSRNSLRNGTEVVSCHPQGSTAGVVYRAGRNNRWYLAVAATYVLPEPETASRCNPAASDHDTAIALKDTEGRSLATQELGRLKLCEGAGSLHFVDAFLWNGSIYFPYYP-YNYTSGAATGWPSMARIAQSTEVLFQGQASLDCGHGHPDGRRLLLSSSLV--EALDVWAGVFSAAAGEGQERRSPTTTALCLFRMSEIQARAKRVSWDFKTAESHCKEGDQPERVQPIASSTLIHSDLTSVYGTVVMNRTVLFLGTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYIYLTAGKEVRRIRVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPKIQIIRSSKEKTTVTMVGSFSPRHS-----KCMVKNVDSSRELCQNKSQPNRTCTCSIPTRATYKDVSVVNVMFSFGSWNLSDRFNFTNCSSLK---------ECPACVETGCAWCKSARRCIHPFTACDPSDYERNQEQCPVAVEKT---SGGGRPKENKGNRTNQALQVFYIKSIEPQKVSTLGKSNVIVTGANFTRASNITMILKGTSTCDKDVIQVSHVLNDTHMKFSLPSSRKEMKDVCIQFDGGNCSSVGSLSYIALPHCSLIFPATTWISGGQNITMMGRNFDVIDNLIISHELKG----NINVSEYCVATYCGFLAPSLKSSKVRTNVTVKLRVQDTYLDCGTLQYREDPRFTGYRVESEVDTELEVKIQKENDNFNISKKDIEITLFHGENGQLNCSFENITRNQDLTTILCKIKGIKTASTIANSSKKVRVKLGNLELYVEQESVPSTWYFLIVLPVLLVIVIFAAVGVTRHKSKELSRKQSQQLELLESELRKEIRDGFAELQMDKLDVVDSFGTVPFLDYKHFALRTFFPESGGFTHIFTEDMHN-RDANDKNESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYLTSILEVLTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFSTVALNVVFEKIPENESADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLELQMGTRQKELLDIDSSSVILEDGITKLNTIGHYEISNGSTIKVFK--------KIANFTSDVEYSDDHCHLILPDSEAFQDVQGKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPNSRAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVF-DIKKTPHIDGCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRDLPPLSSSEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQLLHVKVLFDEKKKCKWM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ARP5-1", "uniprot_id": "A0A8M3ARP5_DANRE", "id": "A0A8M3ARP5-1", "name": "", "aln": "----------MRGYLLGVIVFLKYCICDDVVDFGEDIKDFVVG----------TSKLFVLTENRLYQMRHDLSEEKK---KKDINNSTHPINILVPFDN--------------------NGTLITCGTYEHGYCEVLDINDITNSIYFESKLFMG--PKETEKSIAFIASTSSSRYLLVGKKLDQSTSQSPVVTLRNTVQTQFGGIFSYSE-------EGSDPAIQTTARDVEFVDGFQRASSLDLYLFLNTKTDSEWKVHVLRMDGSKSKKSEIFRSLKSAVIKCCSDKARPVLVSSAVIPSEKTVIWAGVFSAQD-----QQDPENTALALYDISRIQGRVKEFCTQGEKTCS-------SESDLQPLSVVFKSSSMSSVAAVRNGSWIVLFMGNSDGQLIKLVLDENYTPSCPTVLYKSDDERAVFPRMHFDPVDSKYIYIALRKQIRRVSVVRCAKYNTLKDCRSALDPLCGWCVNTQRCSTHDECSNSS----WVSIPKDSLQTELLSFQVAQKPSTQITLHLALSLESTGNPAFSCVFSSGSVNLCNGSDLTAVFPNCSCTFSNQLPN---TGVSATVTVEDQKITKMLILTNCSSITDNSPNVSYTQCVQCISSGCHWSSSSKRCGWTQGREPQLNIQDACKDLLSEYKEP------------------------EILSLEPHKVSFNGRNNVLLRGRNLDSVT--KIRIQGDLGCIAKESPVFDPSSDTLVFNIPPSESKGTVKMCVVTPDNRCHGNSIITYSSQPRCTGVQPRNSWRSGGRKIHVQGTNMEYVESVIVQ-------PSNIFLKSQYDASSRDMWFYSHRIEGSDHFTLSLMVGNSTEACDHDFSYEPDPVFTGFTTLQVAN-DLQVNIQKKADKLNLNISEVKVAGLHGDKG-YQCVVERIESN----AVICKIK----AGPGALDSLNISIGHFYVKQTFESPSGMKYFSILVVLIVIIILGAVVGVIVHRKSQKQMSKKMNDQLELMESNIRRDIRQGFVDLQTEKSDLIDNVGAIPFLDYKHFASRIFFPEAGTLTAVMIRDIGEDSEQTTVDEKCLAFAELIRDKQFLSCFVHALEEQKNFSIKDKCTVASLLTLALHGDLLYLTEIMEDLLQSLMDQSSNANPKLLLRRTESIVEKLLTNWMSICLYGFLRESVGQPLFLLVSALTQQISKGPVDSVTEKALYTLSEDWLLCQAQDFEPLKLKVVFAVG---TGEEISESLEVIALTCDTIQQVKEKILQTFQRKFGFRYTQQIRDIEIEYEKEGKFVMLQEVDDTSEIRGH-VTMLNTLKHYQVGDGACIKVITPKIHAPLKTQNSVKDDKNFSIKYFHLVDPDIDTDLSN----HPEKKALKIKEMYLIKLLSTKVAVHSFVENLFKSIWGLPNNKAPLAVKYFFDFLDEQAERKKITDPDVLHIWKTNSLPLRFWVNILKNPDFVFSDMEKSPHLDGCLSVIAQAFMDSFSLTDTHLDKHSPTNKLLYGKDIPQYKQEVKSYYKLVKDQTSISSQELKTFLQEESKKHQNEFNESAALRELYKYMQRYFTEIFQKLEQTDAPSNLKENMHRVKELFDNMKRSGWN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :: * :. . * * : . :** : . * *: :.*.. . :.: .*.*.*:.: * * *:* *:::* *** :.::... :.. .:. *: : .:.: *. .. ** *. . . .::. : : : . :. :* * . : * .:.***.* .*: : : : * . * .... :*:. : ..* :*:**::: * :******* ::.* .***.*: :*.**.:.: . : : : .* * .: *.::** .. . ***:*..****:*::*.** *..** *:*: .:* .** :: .*:.. ***:: *::**: *..* * :: :* :* ** **** **.: . * .:.... : . : : * :*: :.* . : .*:... . . .. : .*:*.:..: . *.. .:. . .::. : :***:*: :* *: :** *.. ::* . : : : ::. * ::**:*:* *:.**:: * *: .: .: ::* * . * . .** : **. * .:*: .. * . . ::* : *:*: : * .:* ***::* : * *:: ::.:*:. .* :.. *: : . : . . : :.* :.* ** ***: . . : :*:*:***: *::*:. .::.:: :**:: :* .*.* * :::**** *.. * .* :: : :: .*. * . : :*:.* ::: : ...* * * ..*::*:* .:****:**::*::**:**.:** :* *::*..*::********* * ****:* :* :: .*: : : . :*. *: ** :*.** .:*:**:*****:**:* .**:**:**: .*:***.*:* * :.**:*.** :***:******:**********:** *****:**:*::***::*.*:*.***** :* ******.***** *. :*..: *:*** . ::...:.* .* **** *.***::*:* * * * *:.:* :* : : * ::*.:* * . :* ***: **::.:*: ***:. . ....* ::* .: **: ** :: * *: :*:***** ********:**.:*:**:***.***.:**:*:******** ***.********:********************:*** *::*:**:*.***********:****: :*.*.:*******.**** **:******* ::* ..:** *:: ** :*****:*****..** *:***: :** **::***: . .: :::: :** ***: *:. * ", "identical_positions": 506, "similar_positions": 503, "identity": "31.59%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1621", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9HCI7-1", "uniprot_id": "MSL2_HUMAN", "id": "Q9HCI7-1", "name": "E3 ubiquitin-protein ligase MSL2", "aln": "MNPVNATALYISASRLVLNYDPGDPKAFTEINRLLPYFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLT-HSPLPSTSEPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLS-IDRFGINIPSPEH--SNTIDVCNTVDIKTEDLSDSLPPVCDTVATD---LCSTGIDICSFSEDIKP-GDSLLLSVEEVLRSLETVSNTEVCCPN-LQPNLEAT-VSNGPFLQL-SSQSLS------HNVFMSTSPALH------GLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESK---ISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEH-GSKKSHSKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNASTSTS-----VINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q69ZF8-1", "uniprot_id": "MSL2_MOUSE", "id": "Q69ZF8-1", "name": "E3 ubiquitin-protein ligase MSL2", "aln": "MNPVNATALYISASRLVLNYDPGDPKAFTEINRLLPYFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLT-HSPLPSTSEPTADPQASLSPMSESTLSIAIGSSVINGLPTYNGLS-IDRFGINIPSPEH--PNTIDVCNTVDIKTEDLSDNLPPVCDTVATD---LCSTGIDICSFSEDIKP-GDSLLLSVEEVLRSLETVSNTEVCCPN-LQPNLEAT-VSNGPFLQL-SSQSLS------HNVFMSTSPALH------GLSCTAATPKVAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESK---ISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEH-GSKKSHSKSKPGILKKDKAVKEKMPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNASTSTS-----VINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QVJ4-1", "uniprot_id": "F1QVJ4_DANRE", "id": "F1QVJ4-1", "name": "E3 ubiquitin-protein ligase MSL2", "aln": "MNPVNATTLYVSACRSVLQCDPRDPQALAEIYKLLPFFRQSLACLVCGNLLQDPIAPTNSSCQHYVCKSCKGKKMMMKPSCSWCKDYEQFEENKQLCILVDCYKKLCEYIADSPLAQHISSTVEGSSDILSLLNEG------LEGLGEESLSLSLTNQSPTPSTSETLPDEGQSPSTEIKEQGLSPLG---VNGLQDCNGLTNVEELTASLPSLEASVPDSVESSGGDEVKQESFTNEIP-VCEAVAAAGEELCTSTMDICGFSEDIKHDGGTLLLSVEEVLRTLEPDHVSQDECPAILQSTLESSGNLNGPFSSVDSSRQLSSLPQDSHEILVPQHPVSQQNQQHLGISCSAVTPRIPRSNRKRSRSESDSEKIQPLPISTFICGPTLGASAPVQIKCEPKSPAQTIPHMAVVPNGGGLPKVGKTLLVPAKPVKKTLDHHGPKKAYTKSKQGTPKSKEKMKDRILTSALIPGSPTKVVYKKAQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNATGSGAGGMLNVSTAAGSPVASFLATGPHEDKGFDEPLDMRFD-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******:**:**.* **: ** **:*::** :***:*****:* ***:***********:*******:***************************.***:*********:::.**:.* .:*: *****:***:* * .:.*::*.** :** *****. .* * *. :. .:* :*** ***: ::.: .:** * .:::: .. ::* *.:::.:* **::**: **:: :***.****** *.:**********:**. :: ** **..**:: **** .: **:.** *::::. *. : *:**:*.**::.: *************:*******:* ********** :* *.* :: :*.***** **:.**:*:.:*.:**: :* *.**:::*:* * *..: :*::: : ::******.****.***********************************************************************************: * : * ..:****::***:..*:**.:**.:***** ", "identical_positions": 350, "similar_positions": 148, "identity": "57.47%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1623", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LVJ1-1", "uniprot_id": "A0ABK0LVJ1_RAT", "id": "A0ABK0LVJ1-1", "name": "", "aln": "---------------------------------------------------------------------------------MEAFPWAPRSPRRA---------------RAPAPMALVPSARYVSASGPVHPQPFSYWNDYLGLATLITRASD----------RG-----------------SPHEGPGPTPAGPTLGPP--EDDEDDDGDEPEAGGRYLGGALELRALELCAGPAEAGLLEERFAELNPFAGRAAAVLLGCAPSAS----AASTAEVTPREEPSPAWAAEPRLHATSGAT-----AARLLKPELQVCVFCRNNKEAVALYTTHILKGPDGRVLCPVLRRYTCPLCGASGDNAHTIKYCP---LSKVPPPTVRPPPRSTRDNLPSKKLR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80WY3-1", "uniprot_id": "NANO1_MOUSE", "id": "Q80WY3-1", "name": "Nanos homolog 1", "aln": "---------------------------------------------------------------------------------MEAFPWAPRSPRRA---------------RAPAPMALVPSARYVSASGPVHPQPFSSWNDYLGLATLITRASD----------RG-----------------SPHEGPGPTAAGPTMGPP--EDDEDDDGEEPEAGGRYLGGALELRALELCAGPAEPGLLEERFAELNPFAGRAAAVLLGCAPTASTTAAAASTAEVTPREEPSPAWAAEPRLHAASGAT-----AARLLKPELQVCVFCRNNKEAVALYTTHILKGPDGRVLCPVLRRYTCPLCGASGDNAHTIKYCP---LSKVPPPTVRPPPRSNRDSLPSKKLR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WY41-1", "uniprot_id": "NANO1_HUMAN", "id": "Q8WY41-1", "name": "Nanos homolog 1", "aln": "---------------------------------------------------------------------------------MEAFPWAPRSPRRG---------------RAPPPMALVPSARYVSAPGPAHPQPFSSWNDYLGLATLITKAVDGEPR--FGCARGGNGGGGSPPSSSSSSCCSPHTGAGPGALGPALGPPDYDEDDDDDSDEPGSRGRYLGSALELRALELCAGPAEAGLLEERFAELSPFAGRAAAVLLGCAPAAA--AAATTTSEATPREERAPAWAAEPRLHAASGAA-----AARLLKPELQVCVFCRNNKEAMALYTTHILKGPDGRVLCPVLRRYTCPLCGASGDNAHTIKYCP---LSKVPPPPARPPPRSARDGPPGKKLR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FDB3-1", "uniprot_id": "NANO1_DANRE", "id": "E7FDB3-1", "name": "Nanos homolog 1", "aln": "-------------------------------------------------------------------------------------------------------------------MDFLNHN-YLSAR-ASYDYTFNFWNDYLGLSTLVTKNSK------------------------------HSVPQNPNSITESLKAT---LGLDDSPPCPCVMGEGDSGGHLDSCCCPPPASISILDLKERFSILSPFQNQNQGSLLSSSQERE--------IGIGGGFAGFDLFGVERKMRKP----------AARNKQEPKICVFCRNNGAPEEVYGSHVLKTPDGRVVCPILRAYTCPLCSANGDNAHTIKYCP---LSKDQPAQRVLKGGRAVGGKRVKIF--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25724-1", "uniprot_id": "NANOS_DROME", "id": "P25724-1", "name": "Protein nanos", "aln": "MFRSNLEGSGAAAVGVANPPSLAQSGKIFQLQDNFSAFHARGGLNILGLQDMYLDTSGANSSATLSPPITPVTPDPSTSAQSTHFPFLADSAATANSLLMQRQYHYHLLLQQQQQLAMAQHQLALAASAAAASASHQQTDEIARSLKIFAQVTTGAAENAAGSMQDVMQEFATNGYASDDLGRMSYGSAPPQVQMPPQQQHQQQQGLHLPLGRNPAQLQTNGGNLMPIPLATHWLNNYREHLNNVWRNMSYIPAAPNTMGLQAQTAATVSTNLGVGMGLGLPVQGEQLRGASNSSNNNNNNNKVYKRYNSKAKEISRHCVFCENNNEPEAVINSHSVRDNFNRVLCPKLRTYVCPICGASGDSAHTIKYCPKKPIITMEDAIKAESFRLAKSSYYKQQMKV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ::* . ... :: .:.:: * . . . . .. *:: : :. : * . ... . * : ****.** . : :* :: .**:** ** *.**:*.*.**.******** : . . .. : : ", "identical_positions": 33, "similar_positions": 53, "identity": "8.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1629", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62736-1", "uniprot_id": "CALD1_RAT", "id": "Q62736-1", "name": "Non-muscle caldesmon", "aln": "---MLSRSGSQGRR----CLATLSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEAHVQNSAPDEESKPA---TANAQVEGDEE-AALLERLARREERRQKRLQEALERQKEFDPTITDGSLSV-----PSRRMQNNS----AENETAEGEEKGESRSGRYEMEETEVVITSYQKNSYQDAEDKKKEEKE-EEEEEEKLKGGNLGEN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QIKDEKIKKD-KEPKEEVKNFLDRKKGFTEVKAQNG---EFMTHKLKQTENAFSPSRSGGRASGD-KEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKAREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSEDKKPFKCFTPKGSSLKIEERAEFLNKSVQKS-GVKSTHQAAVVSKIDSRLEQYTNAIEGTKASKPMKPAASDLPVPAEGVRNIKSMWEKGSVFSSPSASGTPNKETAGLKVGVSSRINEWLTKSPDGNKSPAPKPSDLRPGDVSGKRNLWEKQ--SVDKVTSPTKV---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9QA16-1", "uniprot_id": "E9QA16_MOUSE", "id": "E9QA16-1", "name": "", "aln": "-MDDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEAHVQNSVPDEESKPA---SSNTQVEGDEE-AALLERLARREERRQKRLQEALERQKEFDPTITDGSLSG-----PSRRMQNDS----AENETAEGEEKRESRSGRYEVEETEVVIKSYQKNSYQDAEDKKKEEKE-EEEQE-KLKGGSLGEN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QIKDEKIKKD-KEPKEEVKSFLDRKKGFTEVKAQNG---EFMTHKLKQTENAFSPSRSGGRASGD-KEAEGAPQVEAGKRLEELRRRRGETENEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKAREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSEDKKPFKCFTPKGSSLKIEERAEFLNKSVQKS-GVRSTHQAAVVSKIDSRLEQYTNAIEGTKASKPMKPAASDLPVPAEGVRNIKSMWEKGSVFSAPSASGTPNKETAGLKVGVSSRINEWLTKSPDGNKSPAPKPSDLRPGDVSGKRNLWEKQ--SVDKVTSPTKV---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05682-1", "uniprot_id": "CALD1_HUMAN", "id": "Q05682-1", "name": "Caldesmon", "aln": "-MDDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTT---TTNTQVEGDDE-AAFLERLARREERRQKRLQEALERQKEFDPTITDASLSL-----PSRRMQNDT----AENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKD-KEPKEEVKSFMDRKKGFTEVKSQNG---EFMTHKLKHTENTFS--RPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPTAAGTPNKETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWEKQ--SVDKVTSPTKV---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58J5D2-1", "uniprot_id": "A0AC58J5D2_DANRE", "id": "A0AC58J5D2-1", "name": "", "aln": "MDDDFERRRELRRQKREEMRLEAERMAYRRSEEDEEEAARERRRRARQERMRSKDSED-VAFQPETPELNNSHSVTVSESISTSVLSSSGTGEGDEEEQALLERLAKREERRMRRMKEALERQKEDEEESSSSSLRRGRSYEPEEQHNNNNNQEEKEEEKQEEEEEEEDVRCREEEEEEEQRVEEKQQRSYLSERESVEEISKIPDEGNNERDAVASSEVREVILNEDVND-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SQVVLEPDVENDASSVHQESSEIERLTENGVDEMREAENFEKDEAEVSENEEALMEDEDVMRKNKQPNGGVCEDSPPKHKKAERTFS--RGSLRSPEAPDADDEDARLEAERKLEELKRRRDEMESEEFEKMRQKQQEAEVELEELKRKREERRKVLEEEERRRKQDEADRKTREEEEKRRMKEEIEKRRAEAAEKRQKVEDSVDGEARKPFKCVSPRGSSLKIGERAEFLNRSAQKS-SVKASHTP-VVSKIDNRLEQYTTAVQGNKEVRSPRSGAIDLPMVTDGIRNIKSMFEKGNVFSSGGSPASTNKDAAGIKVGVAGRINDWLNKTPETGKMSGGRPADLKPGDVTSKRSLWENKGSSATKVTSRGETKSVTNGMGH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* . *: .::**:*.::*****************:*.*:.*: :. .: * : .:*.. .*: .: ::. ***:* *:*****:***** :*::******** : :..** *..: :*:. *:*. * **: *. * * ** * . *:..: . .:. :* .: :* : : . .* : *:::** * .*: : ::: :. : : * ** * . * *::*.:** * . *:. . : .::** ::****:***.* *.*****::****** :******:*************:****:***** ********:*****:***********: :. .: :*****.:*:****** *******:*.*** .*:::* . :*****.******.*::*.* :. :..* ***: ::*:******:***.***: :..:.**::**:****:.***:**.*:*: .* .. :*:**:****:.**.***:: *. **** :. ", "identical_positions": 250, "similar_positions": 171, "identity": "30.34%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1647", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q32Q00-1", "uniprot_id": "Q32Q00_RAT", "id": "Q32Q00-1", "name": "Ankyrin repeat and SOCS box protein 12", "aln": "MNLMDIAKIFSLLQPEKEEEDADTGEKQALNQAVYDNDSCTLDHLLHQERYKRFINSRSGWGIPGTPLRLAASYGHLDCVKVLLEHGADVDSLDVKAQTPLFTAVSHGHLECVRILLEAGACPSGSIYNNCSPVLTASRDGAFAILQELLGHGAEANVKAKLPVWASNIASCSGPLYLAAVYGHLDCFRLLLLYGADPDYNCIDQALLSRVPQPRTLLEICLHHNCEPEYIQLLIDFGANIYLPSLPLDPTSQDDKGIKLLLQARATPRSLLSQARLVIRRSLCRANQPQAIDQLDIPPVLISYLKHQ--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D738-1", "uniprot_id": "ASB12_MOUSE", "id": "Q9D738-1", "name": "Ankyrin repeat and SOCS box protein 12", "aln": "MNLMDIAKIFSLLQPEKEEEDTGTGEKQALNQAVYDNDSCTLDHLLHQERYKRFINSRSGWGIPGTPLRLAASYGHLNCVKVLLEHGADVDSLDVKAQTPLFTAVSHGHLECVRMLLEAGACPSGSIYNNCSPVLTASRDGAFAILQELLGHGAEANVKAKLPVWASNIASCSGPLYLAAVYGHLDCFRLLLLYGADPDYNCTDQGLLSRVPQPRTLLEICLHHNCEPEYIQLLIDFGANIYLPSLPVDPTSQDDKGIKLLLQARATPRSLLSQTRLVIRRSLCRANQSQATDQLDIPPVLISYLKHQ--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WXK4-1", "uniprot_id": "ASB12_HUMAN", "id": "Q8WXK4-1", "name": "Ankyrin repeat and SOCS box protein 12", "aln": "MNLMDITKIFSLLQPDKEEEDTDTEEKQALNQAVYDNDSYTLDQLLRQERYKRFINSRSGWGVPGTPLRLAASYGHLSCLQVLLAHGADVDSLDVKAQTPLFTAVSHGHLDCVRVLLEAGASPGGSIYNNCSPVLTAARDGAVAILQELLDHGAEANVKAKLPVWASNIASCSGPLYLAAVYGHLDCFRLLLLHGADPDYNCTDQGLLARVPRPRTLLEICLHHNCEPEYIQLLIDFGANIYLPSLSLDLTSQDDKGIALLLQARATPRSLLSQVRLVVRRALCQAGQPQAINQLDIPPMLISYLKHQL-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2CEZ8-1", "uniprot_id": "A2CEZ8_DANRE", "id": "A2CEZ8-1", "name": "Ankyrin repeat and SOCS box protein 12", "aln": "-----------MLQLRPVEEDESAAESLELNRAVADDDHFLLAELLSQERYRKCINQQSGWGIPGTPLRMAASKGHLRCLQLLLAHGADVDRLDVKAQTPLFTAVCGRYLSCVLALLRAGANPNGSHLNNSSPVLTAAREGDPEILRQLLQHGAEVNARSKVTLWASGVAVCSGPLYLSAIYGHLDCFKMLLLFGADPNYNSPEEKLNGRATQQKTVMELCLRHGCGVEYIQLLIDFGANVYLPTLIIEKSTKQNEAVELLLKERGCPKSLASQCRLTIRRHLIQVNKIQCLDSLEIPFRLINYLKHKPMNTALVH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** *** .: *. **:** *:* * .** ****:: **.:****:******:*** *** *:::** ****** *************. :*.** **.*** *.** **.******:*:* **::** ****.*.::*:.:***.:* *******:*:*******::***.****:**. :: * .*..: :*::*:**:*.* ************:***:* :: ::::::.: ***: *. *:** ** **.:** * :..: *. :.*:** **.****: ", "identical_positions": 166, "similar_positions": 81, "identity": "52.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1650", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N1G1-1", "uniprot_id": "REXO1_HUMAN", "id": "Q8N1G1-1", "name": "RNA exonuclease 1 homolog", "aln": "MLRSTGFFRAIDCPYWSGAPGGP-----CRRPYCHFRH-RGARGSG----APGDGGEAPPAAGLGYDPYNPELPKPPAQRENGTLGLGEEPRPDVLELELVNQAIEAVRSEVELEQRRYRELLETTREHRSAEAPALAPRGPNASPTVGPDEDAFPLAFDYSPGSHGLLSPDAGYQPTPLAAPAEPGSKYSLASLDRGQGRGGGGGGALEYVPKAVSQP---RRHSRPVPSG--KYVVDNSRPPTDLEYDPLSNYSAR-------HLSRASSRDERAAKRPRGSRGSEPYTPAPKKLCDPFG-----SCDARFSDSEDEAATVPGNEPTTASTPKAR----ADPEIKATGQPPSKEGLEAEGGGLRETKETAVQCDVGDLQPPPAKPASPAQVQ------SSQDGGCPKEGKPKKKKTG-APPAPSCKDGAQGKDKTKDKGRGRP-----VEKPRADKKGPQASSPRRKAERPEGTKKKPSSATPVATSGKGRPDRPARRPSPTSGDSRPAAGRGPPRPLQLPDRKSTKAPSGKLVERKARSLDEGASQDAPKLKKRALSHADLFGDESEDE--AAGPGVPSVWPSALPSLSSDSDSDSDSSLGFPEAQGPPKRLKASPPPSPAP----SSSSSSSSSTSSAGADVDYSALEKEVDFDSDPMEECLRIFNESTSVKTEDRGRLARQPPKEEKSEEK-GLSGLTTLFPGQKRRISHLSKQGQEVEPPRRGPAVPPARPPTAQEVCYLRAQQAQRASASLLQAPARLAEKSPS-VHISAPGEKRRIAHIPNPRLAAAPTGAKRTLAASGSQSSNGPEPGGQQLKTRTLSGMASKTTTTIIPKRIAHSPSLQS--LKKPIIPKEFGGKVPTVIRQRYLNLFIEECLKFCTSNQEAIEKALNEEKVAYDRSPSKNIYLNVAVNTLKKLRG---LAPSAVPGLSKTSGRRVVSHEVVLGGRLAAKTSFSLSRPSSPRVEDLKGAALYSRLREYLLTQDQLKENGYPFPHPERPGGAIIFTAEEKRPKDSSCRTCCRCGTEYLVSSSGRCIRDEECYYHWGRLRRNRVAGGWETQYMCCSAAAGSVGCQVAKQHVQDGRKERLEGFVKTFEKELSGDTHPGIYALDCEMSYTTYGLELTRVTVVDTDVHVVYDTFVKPDNEIVDYNTRFSGVTEADLADTSVTLRDVQAVLLSMFSADTILIGHSLESDLLALKVIHSTVVDTSVLFPHRLGLPYKRSLRNLMADYLRQIIQDNVDGHSSSEDAGACMHLVIWKVREDAKTKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TT28-1", "uniprot_id": "REXO1_MOUSE", "id": "Q7TT28-1", "name": "RNA exonuclease 1 homolog", "aln": "MLRSTGFFRSIDCPYWAGAPGGP-----CRRPYCHFRH-RGARGPG----APGSGGAASPASGLGYDPYNPELPQPPVQRENGALGQGD----GMLELELVNQAIEAVRGEVELEQRRYQELLETARGH-SAGPSALAPCSPATS---IDDDDTFSLALTYTPG--GLLSPDAAYQPTPLAVPAEPGHKYSLAPSDRSQGRAAGGAGALEYVPKAVGQP---RRCGRPVSGG--KYVVDSSKPSTDLEYDPLSNYSAR-------HLGRASARDERATKRPRGSRGAEPYTPALKKPCDPFG-----GCEARFSDSEDDVTSPP---KADVSSPKAG----ADPESKAPGKPVSKEGREHEDGGLRGTKEMAVQYDVEDLGQPPKAPDTVSVVKPGSPARASQDARVPKEGKAKKKKSG-TSASLSHKDKVRKKDKKKEKDPARPR---GKEKVCTDKKKLPASNPRGKAQGPEGTKKKPSSATTVASSGKGGSGRPS---STGPQDS----GPGPHAPLAWKAGSAKKMSSGKLVERKARSLDEGAPQDTPKLKKRALSHAELFGDESEEEDSSLGAGAPRVWPPTLPSLSSDSESDSDSSLGLDETKVP-KRLKAAPPASPVPPSPLSSSSSSSGASQCAEEDVDYSALEKEVDFDVDPMEECLRIFNESTSVKTEDKGRLARQPPKE-KAEEK-THAGLTTLFPGQKRRVSHLCKPGKESEAPKRTPVAPPARPPTAQEVCYRRAQLAQRDSASWLQAAPRPTERLSS-VHISAPGEKRRIAHVPNPRLAAAPTGAKRALSASSSQASHGPEPGSQPLKTRTLSGMASKTTTTVTPKRIAHSPSLQS--LKKPVIPKEFGGKVPTVVRQRYLNLFIEECLKFCSSNQEAIEKALNEEKVAYDRSPSKNIYLNVAVNTLKKLRG---LVPNTVPNLSKASGRRVVSHEVVLGGKLAAKTSFSLSRPSSPRVEELKGTALYSRLREYLLTQEQLKENGYPFPHPERPGGAIIFTAEEKKPKDPSCRICCRCGTEYLVSSSGRCVRSEECYYHWGRLRRNRVAGGWETQYMCCSAAVGSVGCQVAKQHVQDGRKENLEGFVRTFQKELPEDAHAGVFALDCEMSYTTYGLELTRVTVVDTDMQVVYDTFVKPDNEVVDYNTRFSGVTEADLVDTSITLRDVQAVLLSMFSADTILIGHSLESDLLALKVIHGTVVDTSVLFPHRLGLPYKRSLRNLMADYLRQIIQDNVDGHSSSEDASACMHLVIWKIREDAKTKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0S6F3-1", "uniprot_id": "B0S6F3_DANRE", "id": "B0S6F3-1", "name": "", "aln": "MLRSTGFFRGIDCPFYCQNNNGKSGADGCSRPYCHFRHSRQRRGSSGIYDIKKTKALSSNQNDQEYDPFSPEVVRPREQYNGEPPSTGQDVDLGTAELELVNRAIEAVRSELERDKKKLSQIGDQEYEPTTSSVKRHKPPVPSHEG--------------YDPGS-YQMDQASEYTPSPHSS------KYTLDTENTN-------ANALEYVPTAVSKSNIKKLTPRPPSHAKCKYTLDTSKPTTDMEYDPLSNYSAKPTIKEQKTLALAGQRRKRLYSEKQGE--AEEYVPTVKKPKSSFTKADVPKYTASFSESDEESSGTEYR-PVNVSRLKHNRINIGLPKSSAMGQQKKQISKTDAYFSPCESDDTESQ-DVNRTNKKTDKKVSASQTK------TNKTDKVKKENKDSNKKSQKEQQDSSSVDKTSKSSSKKDNSQSKNIEGSSKSKEKSHKDKSASKSAEEKDKKVVKIKTESSHKEKNKSSDGIKKPKMDKPVKTDKVLSKIKDQKNGKLESGSKEKDKKKSSSSNTKDKSKKSISVLDHKEAKKTKQRNLSHVDLFGADSAEE-----------------EDEEDERIVRKSASAFKRGGLVNNKRKSSSS---------SEDDSEVDEDDGGVDTEDFSCLQDVMEYDSDPMEECLRIFNESKEVKMEDKGRQAKQPSRETEEEDEETESTLTTLFPGQKKRVSHFKAQGKSETTMNSVPMQ--QRRMTAQEICYQRMQKAQQQAAQLAEAVKTASASASSNPVLGISGEKRRVAHRPNASLPSS----KPADASSRVLSPTRVVTDQLSVKAQTSAGILSKTISTTVQKRVAHTPTLKSSTMKRPVIPTEFGAKVPTIVRQRYLNIFIDECLKFCSSEQDAFQLALEEEKVVYDRSSSKNIYLNVAVNTVKKLRSRSTPASPVTKSPAVSVNKKAQSHEEVLGGRLAATTSFTINRSGKQHDVNPKGAILYKKLRKYAMTEEQLQEHGYPLPHPEISGHAVVHNLPEKKNNDPFSKICCRCGAEYKVNSNGSCVRKEECSHHWGRLRRNRVPGGWETLYNCCSGAVGSPGCEVCKQHVQDGRKESLDGFVKTFSKPLPVDGNAGVYALDCEMCYTKQGLELTRVTVINSELKVVYDTFVKPGSRVVDYNTRFSGVTADDLENTTISLRDVQAVLLSMFSADSILIGHSLESDLFALKLIHSMVVDTAIVFPHRLGLPYKRALRNLMADYLKRIIQDNVGGHDSSEDARACMELMIWKIKEDAKVKR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 497, "similar_positions": 339, "identity": "38.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1658", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64355-1", "uniprot_id": "EFS_MOUSE", "id": "Q64355-1", "name": "Embryonal Fyn-associated substrate", "aln": "MAIATSAQLARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLLPAGPAPKPSLCPAS---PTQPGSSCPTPERG------CEEQE-VYVIPP--------------------------PARPCSAS-------------GLPARSCSPSS--------------------------------DSIYKVP---------RGNGMQLTASRDVAE-----VYDVP-PNILRAPSSCPYDSPAS------------FSCPVAPVVPQP-------PREDEAPYDVP---LALKPP-AELERDPEWEG----------------------------------------------------------------GREPGPP------------------------LYAAPS----------------------NLKRASALLN---------------------------------------LYEAPEELLAN----------------------------------GESRD-------------------------------------------------ADEGIYDVPLLGPE-PPSPEPPVASSSTDLD-------------TVAQLPTRSS-------------------------------------------------------------------PPQHRPRLPSTESLSRRPLPALPVSEAPAPSPAPSPAPGRKGS-IQDRPLPPPPPCLPGYGGLKPEGDPECREVANDPAGPHNEYEGIPMA----EEYDYVHLKGVDTAQGSRPLDKAFPVDPELLERGLAERKEALSPEEPLVLSTGDLQLLHFYAGQCQSHYSALQAAVAALVASTQANQPPCLFVPHGKRVVVAAHRLVFVGDTLGRLAASAALRAQVGAAGTMLAQTLRATVLAVKGAALGYPSDTAVQEMARCVAELAGQALRFTTLLDGLLP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43281-1", "uniprot_id": "EFS_HUMAN", "id": "O43281-1", "name": "Embryonal Fyn-associated substrate", "aln": "MAIATSTQLARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLLPAGPAPKPSLSPAS---PAQPGSPYPAPDHS------NEDQE-VYVVPP--------------------------PARPCPTS-------------GPPAGPCPPSP--------------------------------DLIYKIP---------RASGTQLAAPRDALE-----VYDVP-PTALRVPSSGPYDCPAS------------FSHPLTRVAPQP-------PGEDDAPYDVP---LTPKPP-AELEPDLEWEG----------------------------------------------------------------GREPGPP------------------------IYAAPS----------------------NLKRASALLN---------------------------------------LYEAPEELLAD----------------------------------GEGGG-------------------------------------------------TDEGIYDVPLLGPEAPPSPEPPGALASHDQD-------------TLAQLLARSP-------------------------------------------------------------------PPPHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGS-IQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMA----EEYDYVHLKGMDKAQGSRPPDQACTGDPELPERGMPAPQEALSPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSLAP--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2KR69-1", "uniprot_id": "A0A0G2KR69_DANRE", "id": "A0A0G2KR69-1", "name": "", "aln": "--MSLSTVLAKALFDNAAESPEELAFRKGDILMVLNQEQDGGP-GWWLCSLHGRQGIAPANRLRLLQSTQAPASSAGTDARRAPSVDSVHLPSSQQGKVNGLSAEDSDGVYLSPPSLAEGVYQSPGAAPAQCRSGELRHSDAGRPRSHSSSGTRPRPDWGDVGVAGRPRSPSLRGRGGESGTLYQTPSSPVPLAAQHRSQVALPTDSVYLTPSAVSRSAAETAGESRYLSPRDASAGHSDGCYLVPRPAVTTLTSENLYQTPTSGAPVAGQCVAGVTSRLVDKIAPKSSPSSSSSPSQSKSGQDAPGMYQTPTPPGGAISRTPQSDRKNPAGTVVVSNASTPGQNIKQTPPSGRGSQKGTTSTAPVGRGKLRESPLLTRTGKSGVPSSPNFGRKPPPPAPPVRSVTRKDLPQSSAIPATKPVLQANPAPPPTNMLEEERQGSKSGQTQADEMKNNSEMLSKRDSASSQEEKLSEEVYDTPPTNRWQHPVSIVPSEEDDGIYNTPRALIVHNDQASEIYDVPTLALNSSEHQQQTYNIPGSAAAIGDAEDEDVYSVPSLPGLPLEASELSGLTVETVVNGRSYSISSLRKQDAIDDVSEPDGGIYDMPALNLEIPTRRLSVSSTGSGDIQWKTSLSALVQSALTSASLPTTPSRDFAAALAEILSIWKAGHVGDIPPVLQHAWSRLSDLLPALSVCGTAPPADGLLSMVRGALEDSAALLQSQTRPRLPSQDSLSRRPLPALPVAEVK---PIAGDMGSRKGSWIQERPLPPPPPAAFPLPPAPVSLVPTVGRMEDEEPG--NEYAGIGLTPTPPPSYPVGDSVGYVKLQG-KPEPPPDTHTEHSSSQLITSTDNKLSPSPPVSMSLEDSELLSFYSSQSLSHLSCLADAIDSLFTSVQGNQPPRVFVSRGKSLIVTAHKLVFIGDTLARLLSSSDLRAKVTTSSGRLCQALKAVVVATKGAAQNYPSVPATQEMVDRVADLSQHAAGFSGLLQRLAEIS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: *: **:**:**:****:**:**:**:* **::* ** ** ******:***.****::** : ** .* . : *: . *:.::. *:.: **: ** ..** . * * .. . .** * :* * .. : :.**. * ** * .*. *: *:* * : :.*:. * :..: *.* : .** . :. : : **:* ** : * *: ::*. * :*. :*::*. *:.. *:. . .* ****:* *. * *. . : .* * : * *.* : .. . ****** :************.*. * .. .**** **:******** . * .: :: .* *** ** :: .* . * . ** :* . . . .: :. .: *** *: :* * :** **:.*. ** *.* *: :*.:*.*.**** :**.:.* ::*:**:***:****.** :*: ***:* ::. * *:*:*.*:*.**** .*** .* ***. *::*: :* *: ** * ", "identical_positions": 217, "similar_positions": 167, "identity": "21.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1662", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LMV6-1", "uniprot_id": "DESP_RAT", "id": "F1LMV6-1", "name": "Desmoplakin", "aln": "MSCNGGSHPRINTLGRMTRAESGPDLRYEMTYSGGGGGGGGGGGG-TSRMYYS--RRCTVNDQNSDGYCQTGTMSRHQNQNTIQELLQNCADCLMRAELIAQPELKFGEGIQLAWNRELDEYFTQANDQMEIIDGLIREMRQMGQPCDAYQKRLLQLQEQMRALYKAISAPRVRRASSK--GGYTCQSGSGWDEFTKRLTGECLGWMRQQRAEMDLMAWGVDSGSVEQHINSHRSIHNAIGDYRWQLDKIKADLREKSAIYQLEEEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAFSIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHLKENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYKRQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSKWYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWHYCMIDIEKIRAMTIAKLKTMRQEDYMKTIEDLELHYQDFIKNSQGSEMFGDDDKRRMQSQFTDAQKHYQTLVIQLPGHPQHQTVTKTEITHVGTCQDVNHNKVIETNRENDKQETWLLMELQKIRRQMEHCEARMTLKNLLLTDQGSTHNITVKINELKSVQNDSQALAEVLNQLKDMLANFRGSEKYCYLQNEIFGLFQKLENINGVTDGYLNSLCSVRALLQAILQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQIHSQSSQQYPLYDLDLGKFTEKVTQLTDRWQKIDKQIDFRLWDLEKQIKQLRNYRDNYQSFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVHKIAELCANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDYYRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFKAKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKTVEDRFDQQKNDYDQLQKARQCEKESLGWQKLESEKAIKEKEYEIERLRVLLQEEGARKREYENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEVELKQVIQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEYQEEAKRRWEYENELSKVRNSYDEEIISLRNKFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEVKRLKNTLAQTTENLRRVEENVQQQKASGSEMSQRKQQLEIELRQVSQMRTEESMRYKQSLDDAAKTIQDKNKEIERLKQLVDKETNERKCLEDENSKLQRVQYDLQKANNSATEAMSKLKVQEQELTRLRIDYERVSQERTVKDQDITRIQSSLKDLQLQKQKAEEELSRLKRTASDESSKRKMLEEELEAMRRSLKEQAVKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHVREKQRTQEELRRLSLDVEALRRQLVQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADNDKNSTISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQESKSQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEETIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRETQSQLETERCRLQKEIDKLRQRPYGSHRETQTEYEWTVDSSKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVASEIQPFLRGAGAIAGASASPKEKYSLVEAKRKKFITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAIARDLIDFDDRQQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQLASGGVVDPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQKNFVDPITKKKVSYMQLRERCRIEPHTGLLLLSVQKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKDFLQGSSCIAGIYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRKFFDQYRSGSLSLTQFADMIS-----LKNGVGTSSGLSGSVNDDVFS--SSRHESVSKISTISSVR--------------------NLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGLIDQDMATRLKPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRSGSRSGSRSGSRRGSFDATGNSSYSYS-YSFSSSSIG-Y", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q557-1", "uniprot_id": "DESP_MOUSE", "id": "E9Q557-1", "name": "Desmoplakin", "aln": "MSCNGGSHPRINTLGRMTRAESGPDLRYEMTYSGGGGGGGGGGGGGTSRTFYSHSRRCTVNDQNSDGYCQTGTMSRHQNQNTIQEMLQNCSDCLMRAELIAQPELKFGEGMQLAWNRELDEYFTQANDQMEIIDGLIREMRQMGQPCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGAGGYTCQSGSGWDEFTKRLTGECLGWMRQQREEMDLMAWGVDAGSVEQHINSHRSIHNTIGDYRWQLDKIKADLREKSAIYQLEEEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAFSIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHLKENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKIIEYKRQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSKWYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWHYCMIDIEKIRAMTIAKLKTMRQEDYMKTIEDLELHYQDFIKNSQGSEMFGDDDKRRMQSQFTDAQKHYQTLVIQLPGHPQHQTVTKTEITHLGTCQDVNHNKVIETNRENDKQETWLLMELQKIRRQMEHCEARMTLKNLLLAEQGSTHHITVKINELKSVQNDSQALAEVLNQLKDMLANFRGSEKYCYLQNEIFGLFQKLENINGVSDGYLNSLCSVRALLQAILQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQIHSQSSQQYPLYDLDLGKFTEKVTQLTDRWQKIDKQIDFRLWDLEKQIKQLRNYRDNYQSFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVHKIAELCANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDYYRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFKAKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKTVEDRFDQQKNDYDQLQKARQCEKENLSWQKLESEKAIKEKEYEIERLRVLLQEEGARKREYENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQMDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSETMQKKQRLEIELKQVIQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEYQEEAKRRWEYENELSKVRNSYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLCEEVKRLKNTLAQTTENLRRVEENAQQQKATGSEMSQRKQQLEIELRQVTQMRTEESMRYKQSLDDAAKTIQDKNKEIERLKQLVDKETNERKCLEDENSKLQRVQYDLQKANNSATEAMSKLKVQEQELTRLRIDYERVSQERTVKDQDITRIQSSLKDLQLQKQKAEEELSRLKRTASDESSKRKMLEEELEAMRRSLKEQAVKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHVREKQRTQEELRRLSLDVEALRRQLVQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNSTISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQESKSQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAESRVKQRLECEKQQIQNDLNQWKTQYSRKEETIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSSRETQSQLESERCRLQKEIEKLRQRPYGSHRETQTEYEWTVDSSKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVASEIQPFLRGAGAIAGASASPKEKYSLVEAKRKKFITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAVARDLIDFDDRQQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQLASGGVVDPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQKNFVDPITKKKVSYMQLRERCRIEPHTGLLLLSVQKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKDFLQGSSCIAGIYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYDTFKELCEQECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRKFFDQYRSGSLSLTQFADMIS-----LKNGVGNSSGLGGSVNDDVFS--SSRHDSVSKISTISSVR--------------------NLTIRSSSLSDPLEESSPIAAIFDTENLEKISIAEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVNQGLIDQDMATRLKPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRSGSRSGSRSGSRRGSFDATGNSSYSYS-YSFSSSSIGGY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15924-1", "uniprot_id": "DESP_HUMAN", "id": "P15924-1", "name": "Desmoplakin", "aln": "MSCNGGSHPRINTLGRMIRAESGPDLRYEVTSGGGG----------TSRMYYS--RRGVITDQNSDGYCQTGTMSRHQNQNTIQELLQNCSDCLMRAELIVQPELKYGDGIQLTRSRELDECFAQANDQMEILDSLIREMRQMGQPCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLGWMRQQRAEMDMVAWGVDLASVEQHINSHRGIHNSIGDYRWQLDKIKADLREKSAIYQLEEEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAFSIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHLKENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYKRQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSKWYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWHYCMIDIEKIRAMTIAKLKTMRQEDYMKTIADLELHYQEFIRNSQGSEMFGDDDKRKIQSQFTDAQKHYQTLVIQLPGYPQHQTVTTTEITHHGTCQDVNHNKVIETNRENDKQETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELKSVQNDSQAIAEVLNQLKDMLANFRGSEKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAILQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQIHSQTSQQYPLYDLDLGKFGEKVTQLTDRWQRIDKQIDFRLWDLEKQIKQLRNYRDNYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVQKIAELCANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADVHARYIELLTRSGDYYRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFKAKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFDQQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVASEIQPFLRGAGSIAGASASPKEKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVVDPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSVQKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKDFLQGSSCIAGIYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRKFFDQYRSGSLSLTQFADMIS-----LKNGVGTSSSMGSGVSDDVFS--SSRHESVSKISTISSVR--------------------NLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRSGSRSGSRSGSRRGSFDATGNSSYSYS-YSFSSSSIGH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PQ61-1", "uniprot_id": "DESPB_DANRE", "id": "A0A8M9PQ61-1", "name": "Desmoplakin-B", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDMQVPSVCLLVPPPNPLAISLASKNSQYYEAILSVWNQLYINVKSMISWQYCLLDIGRINSLTMSMLSKMGPDESNNILRSLEMHFQEFKRHSQGSELFGAEDQKLIENQFAGAQQHFDKLVVDLPTYAARG--EGSEYSAAVSVKMLNELNALRLKLDGAESSLISFLYIALGDDGLEECG----------------QHISSTQAFQKNIQGLRGEFVSLRDGIQAELKDAGNSDKGRYLSGQLDIMNQRLLNLDNYFTTHLQRLDSVKSLLKDMMKAEDVVKVYEARLTEKETASSDPEEVQRYQKVLLSMRSDLEQKQDLLNSLVVDLNQMQKVNDQRDQGRYQCIINLTQYADHVHQLSDRWKRIHVQINNRLVDLDSYLPQLKRYMQSSSQLSGWIDETQKQIDSQHSVKMEDSAAYTQLLNQQKALNSDIKAKRELMETVHKDGETCISAIKNYELELATYSAGLETLLNIPIKRTVLQSPSSSIAEEVSSLNAHYLELLTRSSDYYKLLLASQKNMEELKIRNTRIELLEEELEQLRDAIKDQTANNASLQDALLQYQQELNNSQSHLLSLEEVKRTETMKCMATQESLDSSKDRLEELTEEVRRLKLQLEDMERKKKIVEERYTFLQEEHDETMRKKLKELEQASWAKMELEKTVSERNRELERLRKELEDEARRIKEAQTELAKVRQEHSTEIREVKQTYESQILVAQSSMQKLSQEKESDSAAMSLEFERLEGESSELKEQLKRLRISLSQEEAQRRILEEEVKRLTALNTEESRKRHELESQIQVMMSQKREGDNKMREVQESSSRTLQDKINEINRLTRNFEEERRLKRSLETDK---------------------------------------------------------------------------RRLEGDLAVLKSK---------------------------------------------------------------------------------NETTNEELVQLRSSHRELSLIRVELEAHALEKGRSEQTIARLQARIQELQEELKRLEGELEKQRQVAEEEAGKRRRTESQLEKSSQAMREYTTTITTLRTSQEETNIGAKHADEKCKQLQEALDRASKENKVTSQNLAALKAEINTLKLQLTQEQGRVQDSNQRYEALHRSMEEKSCALNVSSGETERLQRLTETLTKDRQRVEEELRAVRLEHEELLKNKKRGDREMTEQITALQKQLDSSQRAGAEHDRLMRQLSREREKLQVEIENVQKQARETSSVIQTSQSQCSSLSQERDDLLKKITTMEQEIVRLKRLEDELARIKLSLESELRFKSQLQEENNKIKKDFTQWKTKCASHEEQLRQHASERSGLESQFSSVRTELERLRTQLREAEERYRLLLQNFEQE-RTEMQALR-DSKQELLRLQQKPDGATKYTQTD---QTDPSSLVFEGVRKNITAQQLQDCGVIDKVIFEQLMTGKRTVQDVSVDIRLNLKGTGAIAGLAAGPKGKMTFTEAKKQNLISDKSGNMLLEAQAATGYIIDPQANTKMTVEEACLNGVVDEADKKQLLIAEAACVGFRDPKTAKLLPVSQAMKKGIIDRETTLRLLQAQEAAGGILDPILSVYLPKDTAMDRDLVDEDLYQALNAKPDC---YIDPDTDLRASYVTLKKQCKADLNTGLLLLPAPEKPITVQGLRSEVNVSDLVDAKLLEPSDMNHLREGKITSQEIEHRLRAYLRGSTCIAGIYDEAGECTLPIYQAMKNGLLRPGTTLELLEAQAASGFVIDPINNEYYTVEEACQKGLVGVEFKDKLLSAEKAVTGYKEPGTNKLISLFEAIERGLIEKGHGIRLLEAQIASGGIIDPKHSHRIDVDVAYQRGYFDQGMNQILKDEGDDTKGFFDPNTEDNLTYLELKSRCTIDKKTGLVLLPIHDKKK---AQQKNSTRKRRVLIVDPDSNKEMTVREAYEKKLIDYETFLELSQQECEWEETTITAPDGSTSTAIMDMQTGIQYNLKELLAQGVIDQDVFNKYRSGGISVTELAGMITKKTKMLTNPVSSSSSSSLSSSSSSFTSQTTTKSQIVKTETIKSIESTSEYLQQDQSSANSSKHISSMSVKLSPLVESIEEQNPVGAIFDTEKLEKITVCDALKRGMIDSITAQRLLEAQACTGGIVSPDNGRRMSIQEATRVGVLDDEMANRIKPAQKAYIGFEDVKTKRKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLFDPELGCRRSLEEALQMGWLDMRAAQRLQDTRHHPKTLTCPKTKLRISYKEAMEACMNEENTGVRMLPAATVSSRGISSPYNLS-NPGSASGSRSGSRRGSVDYSLSPS-----SSSRYSSFSYSRTSFSSRSLS--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** **** *::*******:.*:.* .*******::*******:**::**:**::** :*.::*:: *..* :: : : .**:*:*:* ::*****:** :*:: ::.**:.**:*::.**::** :. : :* : : : :*. :.:. : :. :.. :: : :*.* ::*: . *.:*. :..: : :: * : .*:* **..:: : *:* *::. :*: * :*::**: ::::**::*********:**.. * ::*: *: * .::.**: *:.** :: .:*:: *:::.* .* ::* :: ::* **:***::*. **: ** **:. : **:.* :. . :. *: ::::: ** .*:*: ** : ::**:** *:.:*..**: * *:* .* * .:**:***:**:*::*************::****. * :*.:.::*:*:******.***::* *.:*:**::**:**:*****. *** .:: :* *:: * :** * .: :::* ****:** :. ::::.**.. .:::**.*:: **. ::** :*::* **:*: ::::*: : : * *. .* *:* **::.*:: *:**** *::*. * :* :.******:.:. *: ::::.**::* :::::::::* :**.** : :::**. *. :**::: **. *: * *** **:. : .* .:* :*::.** ::: ::.*: *.: : :: *.:::*:*** :**:**. :::** : : . *.: **:* : *:. *.::.* : :*: ..:**: :*:: * : *: .:* *:*:* :::** : :: * **.: ::.*.::: **: *.:** ::::* : .**.* . *::.* *::::. :* ::.** :*:: *.::* *. ::::*: ** *** *:::: * * :::::*:** :** *. * **** ***.***:: :***** :***:::* :.:...* : . * *:.**: *:. * : *:.:*.****:*: ***:.**** *:*. ** *:.**:.: ***:.** **..:**: .**:****** * * :**:* *.*.:*: *:::*::*:.****: : :** :*: ***. * : .*:*:*:***:::::. *** * *:: :* :::::: * ::*: :*:*:* *: : ***: .*.*.***:*:**::** ** :* :***. :::*:.**::*::*: :*: *:*:*:*** :*.** * ::.***::::*: :* ********** ****: * *:**:.* ..::* *::*: ** * .** ** :.* :.**:*:**.:***** :***:** *:**::**: **:****.*: *.*:*.***::** *. ::** *. :.**: *:::*: : :******.. ::.::.**:*. *.*::***: :*.** :*.*..*:*: :*: .*:: :*:**:******:*: : .* **:*** **:****:*********:**::**:.* .**** ::****:***:******:*****::* *.::****:*::: ****************:*******.***: **:**:****:: :.:**.* .************:*****:**.** *::*** ***:::*** :.***: *****:****::****:*:***:* ****:** **.:******* ***..**** ..::* :** **:::: : :*::*:..*::****.:*:*::*.**: *.* *..**. . . ... *: :: :..: * .**.*:. .:::: *.: :.:**..*:.******:****:: :.::**::****.*************: * .*:::*:*:*. *::*::**.*:******:****.** *:*************************:*****.***: * * ***:: *::* ******** :.* ********:****:*:: .* *: **:*:* **:***:*:.****:* *** ******** ** . * * * .:: **:*** **** *:. ", "identical_positions": 956, "similar_positions": 807, "identity": "32.83%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1665", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZN63-1", "uniprot_id": "D3ZN63_RAT", "id": "D3ZN63-1", "name": "WD repeat and HMG-box DNA-binding protein 1", "aln": "MPAIQKPMRYGHTEGHTEVCFDDSGSFIVTCGSDGDVRMWEDLD-DDDPKSVNVGEKAFSCALKNGKLVTAVSNNTVQVYTFPEGAPDGILTRFTTNANHVVFNGDGTKIAAGSSDFLVKVVDVMDNSQQQTFRGHDAPVLSLSFDPKDVFLASASCDGTVRVWNIS------------------------DQTCAASWPVLRKSND-------------------VVNSESICRLAWQPKTGKFLAVPVEKSVKLYRRETWSNPFDLSDSS---VTQTLNIVTWSPCGQYLAAGAINGLIVVWNVETKECMERVKHEKGYAICGLAWHPTYSRICYTDVEGNLG-ILENVCDLSGKLSSNKVPSGVEK-DYSDLFDGDDTSSAGDFLNDN--AVEIPSFSKGIRNEEDDNDDLMLAAD------HVLGDDENSVDVTMLR-NDL-HREEGEDRQASSLHSLPLVKSQRPLYDGPMPTPRQKPFQPSSTPLHLTHR-FMAWNSVGIIRCYNDDQDSAIDVEFHDTSIHHATHLSNAFNYTMGSLSHEAVLLACESADELASKLHCLHFSSWDSSKEWIVDMPENEDIEAICLGLGWAAAATSALLLRLFTIGGVQKEVFCLPGPVVSMAGHGEQLCIVYHRGTGFDGDQCLGVQLLELGRK-KKQVLHGDPLPLTRKSYLTWLGFSAEGTPCYVDSEGCVRMLNRGLGNTWTPVCNIREHCKGKSDHYWVVGIHENPQQLRCIPCKGSRFPPTLPRPAVAILPFKLPYCQTSTEKGQMEEQFWHSVLFHNYLDYLAENGYDYEESIKKQAVKEQQELLMKMLALSCKLEREFRCVELADLMTQNAVHLAIKYASRSRKLILAQKLSELAAEKAAELAEIQTEE--REEDFRERLNAGYSHTTTEWSQPRVRSQVEEDAEDREDTVSEGNPEPQNHVIGQNLIQSANSSDTPAMKSGAVFSSSQGRVNPFKVLVSSKEPAVSVNATRSANILDNMNKLSRKSTSFNRVANNEKSPVIKPLIPKPRCKQASAASYFQKRTSQAEKTEEVKE---NPKSSSSEAPAVC-LQNSEVQRPKTGFQMWLEENRSHIMSDNPDISDEADIIKEGMIRFRVLSAEERKEWTNKAKGGTASDGAEAKKRKRGVSEICETEKQEEAVKENLELSKKQKALDLSTNQKLSAFAFKQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59328-1", "uniprot_id": "WDHD1_MOUSE", "id": "P59328-1", "name": "WD repeat and HMG-box DNA-binding protein 1", "aln": "MPATQKPMRYGHTEGHTEVCFDDSGSYIVTCGSDGDVRMWEDLD-DDDPKSVNVGEKAFSCALKNGKLVTAVSNNTVQVYTFPEGVPDGILTRFTTNANHVVFNGAGNKIAAGSSDFLVKVVDVMDNSQQQTFRGHDAPVLSLSFDPKDIFLASASCDGTVRVWNIS------------------------DQTCAVSWPVLQKSND-------------------VVNAKSICRLAWQPKAGKLLAVPVEKSVKLYRRETWSNPFDLSDSS---ISQTLNIVTWSPCGQYLAAGAINGLIVVWNVETKDCMERVKHEKGYAICGLAWHPTCSRICYTDVEGNLG-VLENVCDLSGKVSSNKVSSRVEK-DYNDLFDGDDTSSAGDFLNDN--AVEIPSFSKGIINEDDDNDDIMLAAD------HDLGDDENSVDVTMLK-ADLSHKEEGDDDQARSIHNLPLIRPQRPFYDGPMPTPRQKPFQSSSTPLHLSHR-FMVWNSVGIIRCYNDDQDSAIDVEFHDTSIHHATHLLNAFNYTMGTLSHEAILLACESADELASKLHCLHFSSWDSSKEWMVDMPQNEDIEAICLGLGWAAAATTALLLRLFTIGGVQKEVFCLPGPVVSMAGHGEQLCIVYHRGTGFDGDQCLGVQLLELGRK-KNQVLHGDPLPLTRKSYLTWLGFSAEGTPCYVDSEGCVRMLNRGLGNTWTPVCNIREHCKGKSDHYWVVGIHENPQQLRCIPCKGSRFPPTLPRPAVAILSFKLPYCQTSTEKGQMEEQFWHSVLFHNYLDYLAKNGYDYEESIKNQAVKEQQELLMKMLALSCKLEREFRCVELADLMTQNAVHLAIKYASRSRKLILAQKLSELAAEKAAELAETQSEEE-KEEDFREKLNAGYSHTTTEWSRPRVRSQVED-AEDREDTVSEEKPESHNH--GQNLFQSANSSDTPALKSGAVFSSSQGWVNPFKVVVSSKEPAVSANSTRSANILDSMNKSSRKSTSLNRMENNEKSPVIKPLTPKPRSKQASAASYFQKRTPQADKTEEVKE---NPKSSSSDAPAVC-LQNSENQRPKTGFQMWLEENRSQILSDNPDISDETDIIKEGMIRFRVLSAEERKAWTNKAKGETASDGAEAKKRKRVVSEICETENQEETVKENLDLSKKQKALNLPANQKLSAFAFKQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75717-1", "uniprot_id": "WDHD1_HUMAN", "id": "O75717-1", "name": "WD repeat and HMG-box DNA-binding protein 1", "aln": "MPATRKPMRYGHTEGHTEVCFDDSGSFIVTCGSDGDVRIWEDLD-DDDPKFINVGEKAYSCALKSGKLVTAVSNNTIQVHTFPEGVPDGILTRFTTNANHVVFNGDGTKIAAGSSDFLVKIVDVMDSSQQKTFRGHDAPVLSLSFDPKDIFLASASCDGSVRVWQIS------------------------DQTCAISWPLLQKCND-------------------VINAKSICRLAWQPKSGKLLAIPVEKSVKLYRRESWSHQFDLSDNF---ISQTLNIVTWSPCGQYLAAGSINGLIIVWNVETKDCMERVKHEKGYAICGLAWHPTCGRISYTDAEGNLG-LLENVCDPSGKTSSSKVSSRVEK-DYNDLFDGDDMSNAGDFLNDN--AVEIPSFSKGIINDDEDDEDLMMASGRPRQRSHILEDDENSVDISMLKTGSSLLKEEEEDGQEGSIHNLPLVTSQRPFYDGPMPTPRQKPFQSGSTPLHLTHR-FMVWNSIGIIRCYNDEQDNAIDVEFHDTSIHHATHLSNTLNYTIADLSHEAILLACESTDELASKLHCLHFSSWDSSKEWIIDLPQNEDIEAICLGQGWAAAATSALLLRLFTIGGVQKEVFSLAGPVVSMAGHGEQLFIVYHRGTGFDGDQCLGVQLLELGKK-KKQILHGDPLPLTRKSYLAWIGFSAEGTPCYVDSEGIVRMLNRGLGNTWTPICNTREHCKGKSDHYWVVGIHENPQQLRCIPCKGSRFPPTLPRPAVAILSFKLPYCQIATEKGQMEEQFWRSVIFHNHLDYLAKNGYEYEESTKNQATKEQQELLMKMLALSCKLEREFRCVELADLMTQNAVNLAIKYASRSRKLILAQKLSELAVEKAAELTATQVEEEEEEEDFRKKLNAGYSNTATEWSQPRFRNQVEEDAEDSGEADDEEKPEIHKP--GQNSFSKSTNSSDVSAKSGAVTFSSQGRVNPFKVSASSKEPAMSMNSARSTNILDNMGKSSKKSTALSRTTNNEKSPIIKPLIPKPKPKQASAASYFQKRNSQTNKTEEVKEE--NLKNVLSETPAICPPQNTENQRPKTGFQMWLEENRSNILSDNPDFSDEADIIKEGMIRFRVLSTEERKVWANKAKGETASEGTEAKKRKRVVDESDETENQEEKAKENLNLSKKQKPLDFSTNQKLSAFAFKQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PNN9-1", "uniprot_id": "A0A8M9PNN9_DANRE", "id": "A0A8M9PNN9-1", "name": "WD repeat and HMG-box DNA-binding protein 1", "aln": "MPCERKPMRYGHSEGHTDVCFDDQGKCIVTCGSDGDVRIWESLD-DDDPKSINVGEKVYSVALKNGKLVTAVSNNTVQIHTFPDGEPDGILTRFTTNANHVTFNNSGSRVAAGSSDFLVKMVEVADSSQQKTLRGHDAPVLSVALDPSDEFLASSSCDGSVAVWSIE------------------------SQTQVAQWKVLQKSSD-------------------VTNAKSLCRLAWQPRSGKLIAVPVDLTIQLYERNTWTHVSTLSDDL---ITQVVNVVVWSPCGKFLAAGTVGGNLLIWDVEAKLCIDRQKHEKGFTVCGMAWHPSGGRIAYTDTEGCLG-LLEGVSSSSSTVQSSKATAAKEANDYDDLFDEDDDRMLDEDMSDSRSPVKKPIMED---EDDDDDDDLMPATGRPRNRGSFLDDDDNSQDPSSVK-----LDGLPEEGGSSAVLPAVAPVVSRPVYDGPMPTQPQRAFQPGSTPAHLMHR-FMMWNSVGIVRGYNDDQDNAIDVEFHDTAIHHAMHLTNTLGHTMADLSQEAVLLACEGTDELASKIQCLHFSCWDTHKDWMVDLPKGEDVRALCLGQGWAAVATSALMVRLFSIGGVQKEIFSLPGAVVCMAGHGEQLLIAYHRGTGFDGEQALGVQLLQLGRK-KRQVIHGEPLPLSRKSYLAWMGFSAEGTPCCVDSEGVVRLLNRTLGNTWTPVCNTRETCKSKSDHYWVVGVHENPQQLRCIPCKGARFPPTLPRPAVAVLPFNMPYCQTTTEKGQMEEQYWRSMLFHNHYGFLSSSGYEIDSESQAQAEKEQQELLMKMFALSCKLEREFRCVELAELMTHSVVTLAIRYASRSRRMALAQRLSELALEKANQLQEEEQEDE--EPAYQSREYRESNQMNSRQAQQENGCEEEE-VEEEEYPQEEQMDAEESTETRKKFLNPFKKGGKSPEKPSPKPVSREGRVNPFKVSGAGKSSGSPAGQPRTTNVLDSMT-MSRKPAAFSGLSKQSKAPVLKPLAPKPKSKTQATLLQMSASKGNSKKLEDSQSEAEKVKPAPVAATPPVLKENTENKKPKTGFQLWLEENRKSILADNPDF-EEMDVIKEGMGRFRTLSAEERLNWTEKAKGD-----SDPKKRKR---EDEDEEKAAEQMESDEASAKKKKPLDSSA--KLSAFAFNKE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q01454-1", "uniprot_id": "CTF4_YEAST", "id": "Q01454-1", "name": "DNA polymerase alpha-binding protein", "aln": "MVSVIDKLVFDFGG-KTLVSLAPDNNTLCVANKNGLTKILKTNNPEEEPETLDSSKLVSSIKCYSNSHFLMTTMQGDALRYNIDSSQEELLARFALPLRDCCVIHSGKMAVFGGDDLELILLELDDETHKKHAIKIDEQVSQISYNSQMNILAVSMINGKVQIFSLTSTIPNKVHELNDYIVANSYDDTHRDKILSNMMDDIDKDNDNDLSETADPDENNVADPEFCAANRICTRVAWHPKGLHFALPCADDTVKIFSIKGYSLQKTLSTNLSSTKAHFIDLQFDPLRGTYIAAVDLNNKLTVWNWETSEIHYTREFKR--KITNIAWKIQADSKTLDLVLGTWSGSIAIVQNLAESVVSNIPDQSVAESSTKHGLFVDSESDLENLEGND--DINKSDKLFSDITQEANAEDVFTQTHDGPSGLSEKRKYNFEDEEDFIDDDDGAGYISGKKPHNEHSYSRVHKTHSFPISLANTGKFRYMPFSPAGTPFGFTDRRYLTMNEVGYVSTVKNSEQYSITVSFFDVGRFREYHFEDLFGYDLCFLNEKGTLFGQSKTGQIQYRPHDSIHSNWTK----IIPLQAGERITSVAATPVRVIVGTSLGYFRSFNQFGVPFAVEKTS-PIVALTAQNYRVFSVHYS--QFHG---LSYSLSELGTSSKRYYKRECPLPMSLPNINSDMKKDANLDYYNFNPMGIKSLFFSSYG---------DPCIFGSDNTLLLLSKWRSPEESKWLP----------------ILDSNMEIWKMSGGKETTDIHVWPLALAYDTLNCILVKGKHIWPEFP--------------LPLPSEMEIRMPVFVKSKLLEE--------------NKAILNKKNEIGADTEAEEGEEDKEIQ----------------------------------------------------------------------------------IPVSMAAEEEYLRSKVLSELLTDTLENDGEMYGNENEVLAALNGAYDKALLRLFASACSD--------------------------------------------QNVEKALSLAHELKQDRALTAAVKISERAELPSLVKKINNIREARYEQQLK-----------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 94, "similar_positions": 339, "identity": "7.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1677", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ED65-1", "uniprot_id": "EMAL5_RAT", "id": "Q6ED65-1", "name": "Echinoderm microtubule-associated protein-like 5", "aln": "MAARSAPSCHLRLEWVYGYRGHQCRNNLYYTAAKEIVYFVAGVGVVYSPREHRQKFYRGHSDDIISLALHPERVLVATGQVGKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDLDGQRLVSVGLDSKNAVCVWDWKRGKMLSMAPGHTDRIFDISWDLYQPNKLVSCGVKHIKFWSLCGNALTPKRGVFGKTGDLQTILCLACARDELTYSGALNGDIYVWKGINLIRTIQGAHTAGIFSMNACEEGFATGGRDGCIRLWDLTFKPITVIDLRETEQGY--------KGLSVRSVCWRGDHILVGTQDSEIFEIVVHERNKPFLIMQGHCEGELWALAVHPTKPLAVTGSDDRSVRIWSLVDHALIARCNMDEPIRCAAVNADGVHLALGMKDGSLTVLRVRDMTEVVHIKDRKEAIHELKYSPDGTYLAVGCNDSSVDIYGVAQRYKKVGECVGSLSFITHLDWSSDSKYLQTNDGSGKRLLYKMPGGKEVTSKEEVKGMHWASWTCVAGLEVNGIWPKYSDINDINSVDGNYVGQVLVTADDYGVVKLFRYPCLRKGAKFRKYIGHSAHVTNVRWSHDYQWVISIGGADHSVFQWKFIPERKLKDALHIAPQESLTESNSDESDSDLSDVPELDSEIEQETQLTYHRQVYKEDLPQLKEQCKEKQKSATSKRRERAPGNSIRLHFIHGYRGYDCRSNLFYTQIGEIVYHVAAVGVIYNRQQNTQRFYLGHDDDILCLAIHPLKDYVATGQVGRDPSIHVWDTETIKPLSILKGYHQYGICAVDFSADGKRLASVGIDDSHTIVLWDWKKGEKLSVARGSKDKIFVVKMNPYVPDKLITAGIKHMKFWRRAGGGLIGRKGYVGTLGKNDTMMCAVYGWTEEMAFSGTSTGDVCIWRDVFLVKTVKAHDGPVFSMHALEKGFVTGGKDGVVALWDDSFERCLKTYAIKRADLAPGSKGLLLEDNPSIRAISLGHGHILVGTKNGEILEVDKSGPVTLLVQGHMEGEVWGLATHPYLPICATVSDDKTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVGLNDGSFLMANADTLEDLVSFHHRKDVISDIQFSPGSGKYLAVASHDSFVDIYNVTSSKRVGVCKGATSYITHIDWDSRGKLLQVNTGAKEQLFFEAPRGKKQTIPSVEVEKISWATWTSVLGLCCEGIWPIIGEVTDVTASCLTSDKMVLATGDDLGFVKLFRYPAKGKFGKFKKYVAHSTHVTNVRWTYDDSMLVTLGGADMSLMVWTSEVERHREKKNCDSEESDTDSEEDGGYDSDVTRENEISYTIRALSTNIRPMFGVKPHLQQKEPSVDERQGVVRGSRPPVSRAPPQPEKLQSNNVGKKKRPIEDLVLELAFGYRGRDCRNNVHYLNDGDDIIYHTASVGILHNVATGTQSFYQEHNDDILCLTVNQHPKFINIVATGQVGDSADMSATAPSVHIWDAVNKQTLSILRCSHSKGVCSVSFSATGKLLLSVGLDPEHTVTIWRWQEGAKIASRGGHNQRIFVAEFRPDSDTQFVSVGIKHVKFWTLAGRALLSKKGLLSTLEDARMQTMLAVAFGANNLTFTGTISGDVCVWKDHILCRVVARAHNGPVFAMYTTLRDGLIVTGGKERPSKEGGAVKLWDQELRRCRAFRLETGQVTDCVRSVCRGKGKILVGTRNSEIIEVGEKNAACNILVNGHVDGPIWGLATHPSRDFFLSAAEDGTVRLWDIADKKMLNKVNLGHAARTVCYSPEGDMVAIGMKNGEFIILLVSSLKIWGKKRDRRCAIHDIRFSPDSRYLAVGSSENSVDFYDLTLGPTLNRISYCKDIPSFVIQMDFSADSRHLQVSSGCYKRHVYEVPSGKHLVDHAAIDRITWATWTSILGDEVMGIWSRHAEKADVTCACVSHSGISLVTGDDFGMVKLYDFPCPEKFAKHKRFLGHSPHVTNIRFTSGDRHVVSAGGDDCSVFVWKCVHTPH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BQM8-1", "uniprot_id": "EMAL5_MOUSE", "id": "Q8BQM8-1", "name": "Echinoderm microtubule-associated protein-like 5", "aln": "MAARSAPSCHLRLEWVYGYRGHQCRNNLYYTAAKEIVYFVAGVGVVYSPREHRQKFFRGHSDDIISLALHPERVLVATGQVGKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDLDGQRLVSVGLDSKNAVCVWDWKRGRMLSMAPGHTDRIFDISWDLYQPNKLVSCGVKHIKFWSLCGNALTPKRGVFGKTGDLQTILCLACARDELTYSGALNGDIYVWKGINLIRTIQGAHTAGIFSMNSCEEGFATGGRDGCIRLWDLTFKPITVIDLRETEQGY--------KGLSVRSVCWRGDHILVGTQDSEIFEIVVHERNKPFLIMQGHCEGELWALAVHPTKPLAVTGSDDRSVRIWSLVDHALIARCNMEEPIRCAAVNVDGIHLALGMKDGSFTVLRVRDMTEVVHIKDRKEAIHELKYSPDGAYLAVGCNDSSVDIYGVAQRYKKVGECVGSLSFITHLDWSSDSRYLQTNDGSGKRLLYKMPGGKEVTSKEEIKGMHWASWTCVAGLEVNGIWPKYSDINDINSVDGNYVGQVLVTADDYGVVKLFRYPCLRKGAKFRKYIGHSAHVTNVRWSHDYQWVISIGGADHSVFQWKFIPERKLKDALHIAPQESLAESNSDESDSDLSDVPELDSEIEQETQLTYHRQVYKEDLPQLKEQCKEKQKSATSKRRERTPGTSIRLHFIHGYRGYDCRSNLFYTQIGEIVYHVAAVGVIYNRQQNTQRFYLGHDDDILCLAIHPLKDYVATGQVGRDPSIHVWDTETIKPLSILKGYHQYGICAVDFSADGKRLASVGIDDSHTIVLWDWKKGEKLSVTRGSKDKIFVVKMNPYVPDKLITAGIKHMKFWRRAGGGLIGKKGYVGTLGKNDTMMCAVYGWTEEMAFSGTSTGDVCIWRDVFLVKTVKAHDGPVFSMHALEKGFVTGGKDGMVALWDDSFERCLKTYAIKRADLAPGSKGLLLEDNPSIRAISLGHGHILVGTKNGEILEVDKSGPITLLVQGHMEGEVWGLATHPYLPICATVSDDKTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVGLNDGSFLMANADTLEDLVSFHHRKDIISDIRFSPGSGKYLAVASHDSFVDIYNVTSSKRVGVCKGATSYITHIDWDSRGKLLQVNTGAKEQLFFEAPRGKRQTIPSVEVEKISWATWTSVLGLCCEGIWPVIGEVTEVTASCLTSDKMVLATGDDLGFVKLFRYPAKGKFGKFKKYVAHSTHVTNVRWTYDDSMLVTLGGADMSLMVWTNEVESHREKKYCDSEESDIDSEEDGGYDSDVTRENEISYTIRALSTNIRPMFGVKPHLQQKEPSVDERQGVVRGSRPPVSRAPPQPEKLQSNNVGKKKRPIEDLVLELAFGYRGRDCRNNVHYLNDGDDIIYHTASIGILHNVATGTQSFYQEHNDDILCLTVNQHPKFINIVATGQVGDSADMSATAPSVHIWDAVNKQTLSILRCSHSKGVCSVSFSATGKLLLSVGLDPEHTVTIWRWQEGAKIASRGGHNQRIFVAEFRPDSDTQFVSVGIKHVKFWTLAGRALLSKKGLLSSLEDARMQTMLAVAFGANNLTFTGTISGDVCVWKDHILCRVVARAHNGPVFAMYTTLRDGLIVTGGKERPSKEGGAVKLWDQELRRCRAFRLETGQVTDCVRSVCRGKGKILVGTRNSEIIEVGEKNAACNILVNGHVDGPIWGLATHPSRDFFLSAAEDGTVRLWDIADKKMLNKVNLGHAARTVCYSPEGDMVAIGMKNGEFIILLVSSLKIWGKKRDRRCAIHDIRFSPDSRYLAVGSSENSVDFYDLTLGPTLNRISYCKDIPSFVIQMDFSADSRHLQVSSGCYKRHVYEVPSGKHLVDHAAIDRITWATWTSILGDEVMGIWSRHAEKADVTCACVSHSGISLVTGDDFGMVKLYDFPCPEKFAKHKRFLGHSPHVTNIRFTSGDRHVVSAGGDDCSLFVWKCVHMPH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05BV3-1", "uniprot_id": "EMAL5_HUMAN", "id": "Q05BV3-1", "name": "Echinoderm microtubule-associated protein-like 5", "aln": "MAARSAPSCHLRLEWVYGYRGHQCRNNLYYTAAKEIVYFVAGVGVVYSPREHRQKFYRGHSDDIISLALHPERVLVATGQVGKEPYICIWDSYTVQTISVLKDVHTHGIACLAFDLDGQRLVSVGLDSKNAVCVWDWKRGKMLSMAPGHTDRIFDISWDLYQPNKLVSCGVKHIKFWSLCGNALTPKRGVFGKTGDLQTILCLACARDELTYSGALNGDIYVWKGINLIRTIQGAHAAGIFSMNACEEGFATGGRDGCIRLWDLTFKPITVIDLRETDQGY--------KGLSVRSVCWRGDHILVGTQDSEIFEIVVQERNKPFLIMQGHCEGELWALAVHPTKPLAVTGSDDRSVRIWSLVDHALIARCNMEEPIRCAAVNADGIHLALGMKDGSFTVLRVRDMTEVVHIKDRKEAIHELKYSPDGTYLAVGCNDSSVDIYGVAQRYKKVGECLGSLSFITHLDWSSDSRYLQTNDGNGKRLFYRMPGGKEVTSTEEIKGVHWASWTCVSGLEVNGIWPKYSDINDINSVDGNYIGQVLVTADDYGIIKLFRYPCLRKGAKFRKYIGHSAHVTNVRWSHDYQWVISIGGADHSVFQWKFIPERKLKDAVHIAPQESLADSHSDESDSDLSDVPELDSEIEQETQLTYRRQVYKEDLPQLKEQCKEKQKSATSKRRERAPGNSIRLHFVHGYRGYDCRSNLFYTQIGEIVYHVAAVGVIYNRQQNTQRFYLGHDDDILCLTIHPLKDYVATGQVGRDPSIHIWDTETIKPLSILKGHHQYGVSAVDFSADGKRLASVGIDDSHTVVLWDWKKGEKLSIARGSKDKIFVVKMNPYVPDKLITAGIKHMKFWRKAGGGLIGRKGYIGTLGKNDTMMCAVYGWTEEMAFSGTSTGDVCIWRDIFLVKTVKAHDGPVFSMHALEKGFVTGGKDGIVALWDDSFERCLKTYAIKRAALAPGSKGLLLEDNPSIRAISLGHGHILVGTKNGEILEVDKSGPITLLVQGHMEGEVWGLATHPYLPICATVSDDKTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVGLNDGSFLMANADTLEDLVSFHHRKDMISDIRFSPGSGKYLAVASHDSFIDIYNVMSSKRVGICKGATSYITHIDWDIRGKLLQVNTGAKEQLFFEAPRGKKQTIPSVEVEKIAWASWTSVLGLCCEGIWPVIGEVTDVTASCLTSDKMVLATGDDLGFVKLFRYPTKGKFGKFKRYVAHSTHVTNVRWTYDDSMLVTLGGTDMSLMVWTNEMEGYREKRPCDSEESDIDSEEDGGYDSDVTRENEISYTIRALSTNIRPMLGIKPHLQQKEPSIDE--------RPPVSRAPPQPEKLQTNNVGKKKRPIEDLVLELIFGYRGRDCRNNVHYLNDGDDIIYHTASVGILHNVATGSQSFYQEHNDDILCLTVNQHPKFINIVATGQVGDSADMSATAPSIHIWDAMNKQTLSILRCYHSKGVCSVSFSATGKLLLSVGLDPEHTITIWRWQEGAKIASRAGHNQRIFVAEFRPDSDTQFVSVGVKHVKFWTLAGRALLSKKGLLSTLEDARMQTMLAIAFGANNLTFTGTISGDVCVWKDHILCRIVARAHNGPVFAMYTTLRDGLIVTGGKERPSKEGGAVKLWDQELRRCRAFRLETGQATDCVRSVCRGKGKILVGTRNAEIIEVGEKNAACNILVNGHVDGPIWGLATHPSRDFFLSAAEDGTVRLWDIADKKMLNKVNLGHAARTVCYSPEGDMVAIGMKNGEFIILLVSSLKIWGKKRDRRCAIHDIRFSPDSRYLAVGSSENSVDFYDLTLGPTLNRISYCKDIPSFVIQMDFSADSSYLQVSSGCYKRHVYEVPSGKHLMDHAAIDRITWATWTSILGDEVLGIWSRHAEKADVNCACVSHSGISLVTGDDFGMVKLFDFPCPEKFAKHKRFLGHSPHVTNIRFTSGDRHVVSAGGDDCSLFVWKCVHTPH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T6P4-1", "uniprot_id": "A0AB32T6P4_DANRE", "id": "A0AB32T6P4-1", "name": "", "aln": "MADRTAPNCHLRLEWVYGYRGHQCRNNLYYTAAKEIVYFVAGVGVVYNTREHKQKFYLGHNDDIISLALHPERVLVATGQVGKEPYICVWDSYTVQTVSILRDMHTHGIACLAFDLDGQCLVSVGLDSKNTICVWDWRQGKVLAAAPGHTDRIFDISWDLYQQSKLVSCGVKHIKFWSLCGNALTPKRGVFGKTGDLQTILCLACARDEITYSGALNGDIYVWKGINLIRTVQGAHGSGIFSMNACEEGFATGGRDGCIRLWDLNFKPITVIDLRETDQGYKVARGENSRGLSVRSVCWRGDHILVGTQDSEIFEVVVHDRTKPFLIMQGHCEGELWALAVHPTKPLAMTGSDDRSVRIWSLVDHALIARCNMEEPIRCAAVSTDGIHLALGMKDGSFTVLRVRDMTEVVHIKDRKEAIHELKYSPDGAHLAVGSNDNSVDIYGVVQRYKKVGECVGSSSFITHMDWSTDSKYLQTNDGNGRRLFYRMPSGKEVTNREELKLVQWSSWTCVLGPEVNGIWPKYSDINDINSVDANFSSQVLVTADDYGLVKLFRYPCIRKGAKFKKYLGHSAHITNIRWSHDYQWVITIGGADHSVFQWKFVPERKSKDTLHIAPQETLIDSHSEESDSDQSDVPEMDSEIEQETQLTYRRQVYKEDLPQLKEQCKEKHRAMAMKKRERAPASGMRLHFIHGYRGYDCRSNLFYTQTGEIVYHVAAVGVVYNRQQNTQRFYLGHDDDILCLAIHPVKDYVATGQVGRDSSIHIWETEFLKPLSVLKGFHQFGVCALDFSADGKRLASVGLDDNHTIVLWEWRKGEKLSTIRGSKDKIFVIKINPYMPDKLISAGVKHMKFWHRAGGGLIGKK---GSMGKTETMMCAVYGWTEEMVFSGTCTGDICIWRDMFLVKTVKAHDGPVFSMHALEKGFVTGGKDGIVALWDDTFERCLKTYAIKRAVLAPGSKGLLLEDNPSIRAISLGHGHILVGTKNGEILEVDKNGPITLLVQGHMEGEVWGLATHPHLPLCATVSDDKTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVGLNDGSFLIVNADTLEDLVSFHHRKDIISEIRFSPVTGKYLAVASGDSFVDIYNVMSSKRVGVCKGSMNYITHLDWDKRGKLLQVNTSAKEQLFFEAPRGKKQSIPVTEVEKIDWSTWTCVLGSSCEGIWPVVSEVTEVTAACLSYDKKLLATGDDLGYVKLFKYPVKGKYAKFKRYMAHSTHVTNVRWSHDDSLLASVGGSDTCLMIWNHETESCREARQCDSEESDIESEDDGGYDSDVTRENEIVYVIKALSTNMRPMTGVKPHLQQKEPTVDE--------RPPVSRAPPMPEKLQTNNVGKKKRPIEDLVLELVFGYRGNDCRNNVHYLNEGADIIYHTASIGVVLNLTTACQSFYLEHSDDILCLTINQHPKFPNVVATGQVGDTGDMSATSPSIHVWEAMNKQTLSVLRCHHSRGVCSVSFSATGKLLLSVGLDPQHTLTIWKWQEGAKVASRAGHTQRIFVAEFRPDSDTQFVSVGIKHVRFWTLAGRALLSKKGVLSSIEDARMQTMLSVAFGANNLTFTGTISGDVCVWKEHILVRIVAKAHTGPVFTMYTTLRDGLIVTGGKERPSKEGGALKLWDQELKRCRAFRLETGQVIDCVRSVCRGKGKILVGTRNAEIIEVGEKNAACNILVNGHMDGPVWGLGAHPTRDVFLSAAEDGTVRLWDISQRKMLNKVNLGHPARTVSYSPEGDMVAIGMKNGEFIILLVTSLKIWGKKRDRRSAIQDIRFSPDSRYLAVGSSENAVDFYDLTLGPQLNRINCCRDIPSFVMQMDFSADSCFVQLSTGAYKRVVYEVPSGKQVTEQAVIDRITWATWTSVLGDEVVGIWSRNTDKADVTCACVSHSGINIVTGDDFGMVKLFDFPCPEKFAKHKRFLGHSAHLTNVRFTNGDRFVVSAGGDDRSLFVWRCVHTPH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *:**.***************************************..***:***: **.***************************:********:*:*:*:*************** **********::*****::*::*: ***************** .*********************************************:*********************:**** :******:*******************.************:*** :*************************:**::*.**************************:************************:********..**:**********:******************************::****.**.*******.*********:** *****:***:**:*******.*:**:*:**.*****. **:* ::*:***** * *******************.*: .**********::*******:******:**:*****:**:**********:*************:**** **::******:* :*:*:***** *****:************:******************::: : *:***:*...:****:**************** ************:*********************:***:************.***:*:** :****:***.**:*:.*:*************:**.**:***:*:****** *********:*:***:*****:**:******::*******:* *::**.:*************.****.***:*****:******************************:******:************* ****************************************.**:*******************:**:*****************************************************:.****************:**:*:*** :******** ***:***** ******:***: .****:*** *********.*************:*:** .***** *::**.*** .******::.***:***:**: ** :********:****:**.***:.***:*:***********::***:*.::**:* .**:*. * * ** : ******* :**:************** *.*:*****:*** *:*********::** ********* *****:***************** *****.**********:* ********:*:: *::*. **** **.*******:****** *:********:.*****:**:*:*:*:******:*** **:*********************:**:***:******:***.**.********************:***:**************:**::*********::*********************:*** *:**:**.****:************************:*******:***********. *******************:*******************:***:***.:**:**.***************:::**********.****.**********************:************.**:******************:********** ****. *:******:******** .:*:*:*.*** ********:: ::*.***********:*****:*****:::****.*********.:***********:******************.*:**:***.***.******** *:***:*** **", "identical_positions": 1641, "similar_positions": 266, "identity": "82.67%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1684", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H2G2-1", "uniprot_id": "SLK_HUMAN", "id": "Q9H2G2-1", "name": "STE20-like serine/threonine-protein kinase", "aln": "MSFFNFRKIFKLGSEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFV-TVDSNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSLPIPASKRASSDLSIASSEEDKLSQNACILESVSEKTERSNSEDKLNSKILNEKPTTDEPEKAVEDINEHITDAQLEAMTELHDRTAVIKENEREK-RPKLENLPDTEDQETVDINSVSEGKENNIMITLETNIEHNLKSEEEKDQEKQQMFENKLIKSEEIKDTILQTVDLVSQETGEKEANIQAVDSEVGLTKEDTQEKLGEDDKTQKDVISNTSDVIGTCEAADVAQKVDEDSAEDTQSNDGKEVVEVGQKLINKPMVGPEAGGTKEVP-IKEIVEMNEIEEG----KNKEQAINSSENIMDINEEPGTTEGEEITESSSTEEMEVRSVVADTDQKALGSEVQDASKVTTQIDKEKKEIPVSIKKEPEVTVVSQPTEPQPVLIPSININSDSGENKEEIGSLSKTETILPPESENPKENDNDSGTGSTADTSSIDLNLSISSFLSKTKDSGSISLQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRFLQKEEQRAQQQLNSKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNMLKNRKKEVINEVEKAPKELRKELMKRRKEELAQSQHAQEQEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSLRINST-ATPDQDRDKIKQFAAQEEKRQKNERMAQHQKHENQMRDLQLQCEANVRELHQLQNEKCHLLVEHETQKLKELDEEHSQELKEWREKLRPRKKTLEEEFARKLQEQEVFFKMTGESECLNPSTQSRISKFYPIPSLHSTGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O54988-1", "uniprot_id": "SLK_MOUSE", "id": "O54988-1", "name": "STE20-like serine/threonine-protein kinase", "aln": "MSFFNFRKIFKLGSEKKKKQYEHVKRDLNPEEFWEIIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSKWSSNFKDFLRKCLEKNVDARWTTSQLLQHPFV-TVDSNKPVRELIAEAKAEVTEEVEDGKEEDEEEEAENALPIPANKRASSDLSIASSEEDKLSQNACILESVSERTEQSTSEDKFSNKILNEKPTTDGPEKAVD---EHASDVNLETGAELNDQTVGIHENGREKKRPKLENLPDTQDQQTVDVNSVSEENENN-RVTLETNTDC-LKPEEDRNKENQETLESKLIQSEEINDTHIQTMDLVSQETGEKEADFQAVDNEVGLTKEETQEKLGKDGTAQKVITSDRSSEVGTDEALDDTQKAAELS-KAAQSGEGDEALAPTQTLAEKPTEGPEAGGAEEEPPGGERVEDKQPEQQPAVCEAEGQLTSTSETTRATLEQPETDEVEQVSESNSIEELER-LVVTGAEARALGSEGE-AAATEVDLERKENAQKVPVKAESQAPAASQPSEPHPVLIPSININSETTENKEEMGALPKPETILPPEPEHEKGNDTDSGTGSTVENSSGDLNLSISSFLSKAKDSGSVSLQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRLLQKEEQRAQQQLNGKLQQQREQIFRRFEQEMLSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNVLKNRKKEVMNEVEKAPRELRRELTKRRKEELAQSQHAQEQEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSLRINST-ATPDQDREKIKQFAAQEEKRQKNERMAQHQKHESQMRDLQLQCEANVRELHQLQNEKCHLLVEHETQKLKELDEEHSQELKEWREKLRPRKKTLEEEFARKLQEQEVFFKMTGESECLNPSAQSRISKFYPIPTLHSTGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B8A4S3-1", "uniprot_id": "B8A4S3_DANRE", "id": "B8A4S3-1", "name": "non-specific serine/threonine protein kinase", "aln": "MSFFNFRKIFKLGIEKKKKQYDHVHRDTNPEEIWEIVGELGDGAFGKVFKAQNKQTGIFAAAKVIDTKTEDELEDYMVEIDILASCDHHNIVKLLDAFYFESKLWILIEFCAGGAVDAVMLELERPLTEPQIRVVCKQTLDALLYLHDNKVIHRDLKAGNILLTLDGDVKLADFGVSAKNTKTVQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADIWSLGITLIELAQIEPPNHEMNPMRVLLKIAKAEPPTLLQPSKWSPEFRDFLKHALEKNVDNRWSTAQLLQHPFVSTVTDSRPLRELIAEAKAEVTEEMEE--EEDDEEHEGN---LLGHKRAPSDASVGSSEDEKLPQSPSTLESVPERIEEVSAP-KLADDIVTAEIKKE-------------------------------------------EDPLKTEENHILDK-AASESNKQE------------LKTEGEPDVVPSETPAEGIIQP--------------AKPDGEK-------------LREE--EVLGNGELVQKEPASDVCS------PTDKEKAVIEES---------SKAVAPSSPVPEKEK--------------KEKLEDEQ--------------------------------------------------------------------------KQSPVKPHYVKKE----------------------DSDSG---------------------------ISSTTDTSSNSSSIDLNLSISSFISKSKEMGTNSQQDNKRQKKTLKKTRKFMVDGVEVSVTTSKIITDNDTKNEEMRFLRRQELRELRLLQKEEQRAQQQLSNKLQQQRDQICRRFEHETTSKKRQYDTEVENMERQQKQTIERLEQEHTERLRDEAKRIKAEQDKELSKFQNTHKNRKK-------------------------------EEQEFVQKQQQDLDSALKKIIQQHKLELATTERDCLNHKQQLLRAREAAMWELEERHLQEKHQLYKQQLKDQYFMQRHQLLKRHEKEMEQMHRYNQRLMEDMKNRQMQEKTRLPKIQRSDAKTRMAMFKKSLRITTTGVTAELERERVKQFAAQEEKRQKNERLHQQQKHENQMRDLQTQCDANSRELQQLQNEKCHLLIEHETQKLKELDEEHGAELKDWREKLRPRKKALEEEFARKLQEQEVFFKMSGESACLNPSTQSRISKFYPVPSVQSTGF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************* *******:**:** ***::***:***********:*****:*.::*********:*:***************** **********:*.:**************************.**:*******:** ******:***********:*****:************:*:*********************************:*********:*:****:**:***********:***** ***:**.:*:***::.****** **:*:******** ** ..:*:**************:*: ***:**. * : . ***.** *:.***::**.*... ****.*: *. .: *: ..*:. : ..: *: .*:::. :* :.** :::: **.* : : .: . :*:. :: *** :*: * **:. .** *: .. . * : . * * .:.: . : :* * :* :: ::. :* * :*:: .* *.:: :.** *********:**:*: *: * *:.:************:*************:**.*:*.**:************:************..******:** ****:* ******* *:**:*:**************:**********.**:******** ***** :**********:**.:*******:* ***. **:***:****:******:************** ********************** ***:******:*::**** **::********:**************.:* .*.: :*:::***************: *:****.****** **:** ***:**********:**************. ***:**********:******************:*** *****:*********:*:::*** ", "identical_positions": 681, "similar_positions": 194, "identity": "54.79%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1689", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08587-1", "uniprot_id": "NUP50_RAT", "id": "O08587-1", "name": "Nuclear pore complex protein Nup50", "aln": "-MAKRVAEKELTDRNWDEEDEVEEMGTFSVASEEVMKNRAVKKAKRRNIGFESDSG------------GAFKGFKGLVVP--SGGGG-----------------------FSGFGGGSGGKPLEGLTNGNSTDSATPFSSAKTAAEPKAAFGSFAVNGPTTLVDKKISSPKCN-SSNQPPSSGPASSTSCTGNTYHKQLAGLNCSVRDWIVKHVNTNPLCDLTPIFKDYERYLATIEKQLENGGSSSSERQTDRATAAMEPPSLFGSTKLQQDSPFSFHG-------------------------NKAEDTS-EKLEFTAEKKSD-------------------AAQGATSASFNFGKKIESSVLG--SLSSGSLTGFSFSP----------------GNSSLFGKDAAQSKAASSPFSAKASESQAGGSSSECRDGEEEESDEPPKVVVTEVKEEDAFYSKKCKLFYKKDNEFKEKGVGTLHLKPT-ATQKTQLLVRADTNLGNILLNVLIPPNMPCTRTGKNNVLIVCVPNPPLDEKQPTLPVTMLIRVKTSEDADELHKILLQKKDV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIH2-1", "uniprot_id": "NUP50_MOUSE", "id": "Q9JIH2-1", "name": "Nuclear pore complex protein Nup50", "aln": "-MAKRVAEKELTDRNWDEEDEVEEMGTFSVASEEVMKNRAVKKAKRRNVGFESDSG------------GAFKGFKGLVVP--SGGGG-----------------------FSGFGG-SGGKPLEGLTNGNSTDNATPFSNVKTAAEPKAAFGSFAVNGPTTLVDKKISSPKCN-NSNQPPSSGPASSTACPGNAYHKQLAGLNCSVRDWIVKHVNTNPLCDLTPIFKDYERYLATIEKQLENGGGSSSESQTDRATAGMEPPSLFGSTKLQQESPFSFHG-------------------------NKAEDTS-EKVEFTAEKKSD-------------------AAQGATSASFSFGKKIESSALG--SLSSGSLTGFSFSA----------------GSSSLFGKDAAQSKAASSLFSAKASESPAGGGSSECRDGEEEENDEPPKVVVTEVKEEDAFYSKKCKLFYKKDNEFKEKGVGTLHLKPT-ATQKTQLLVRADTNLGNILLNVLIAPNMPCTRTGKNNVLIVCVPNPPLDEKQPTLPATMLIRVKTSEDADELHKILLEKKDA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKX7-1", "uniprot_id": "NUP50_HUMAN", "id": "Q9UKX7-1", "name": "Nuclear pore complex protein Nup50", "aln": "-MAKRNAEKELTDRNWDQEDEAEEVGTFSMASEEVLKNRAIKKAKRRNVGFESDTG------------GAFKGFKGLVVP--SGGGR-----------------------FSGFGSGAGGKPLEGLSNGNNITSAPPFASAKAAADPKVAFGSLAANGPTTLVDK-VSNPKTNGDSQQPSSSGLASSKACVGNAYHKQLAALNCSVRDWIVKHVNTNPLCDLTPIFKDYEKYLANIEQQHGNSG-RNSESESNKVAAETQSPSLFGSTKLQQESTFLFHG-------------------------NKTEDTPDKKMEVASEKKTDP------------------SSLGATSASFNFGKKVDSSVLG--SLSSVPLTGFSFSP----------------GNSSLFGKDTTQSKPVSSPFPTKPLEGQAEGDSGECKGGDEEENDEPPKVVVTEVKEEDAFYSKKCKLFYKKDNEFKEKGIGTLHLKPT-ANQKTQLLVRADTNLGNILLNVLIPPNMPCTRTGKNNVLIVCVPNPPIDEKNATMPVTMLIRVKTSEDADELHKILLEKKDA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TP02-1", "uniprot_id": "A0AB32TP02_DANRE", "id": "A0AB32TP02-1", "name": "Nuclear pore complex protein Nup50", "aln": "-MAKRIAEKELTDRNWDQEDDGEEAGTFSIASDDVMKNRAIKKAKRRNV-AEGESG------------GAFKAFKGFSLAPATATAS-----------------------FSGFGNGAGFKPMASLTNGSVASVAPSFTGFNVPASAKTNS------GPLTFSSSTPSKPTDG----EVTSNGSAPSS----KEYNRQLTALNCSVRDWITKHVNDNPLCDLNPIFRDYERHLASIERKYGSGAADETPGKPLASCAAAP-----QTVSLK----------------------------------NKDDKPP-------AEKPAA-----------------------PPGVSFNFGKKVDSSVLG--ALSSGGAPSFSFSS----------------SSSSSAVFGSAVS-SVSSPVVNSDSNSQTADENG-------EDSEEPPVPVVKEIKEKDAFYSKKCKLFYKKDGEFKEKGVGTLHLKMT-TESKLQLLVRADTNLGNILLNIMVPSSMPCSRTGKNNVMVVCVPNPPVDDKNPSVPVPVLIRVKTAEDADQLHRVLQEKKA-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7K0D8-1", "uniprot_id": "NUP50_DROME", "id": "Q7K0D8-1", "name": "Nuclear pore complex protein Nup50", "aln": "MAGKRQATSNLNHENWDLEEEPEERGTFRTATEEELKTRVIKKARRKIAGGSSAAEEDGAEEKTAEPKSVFSGFSGFGKPAASPAAGSPFSFLANVTAPATTSSSEPKKSAFSFGFSSSSSSADRPVSTSICGTASTSSTAPSPLPAKESTSTVDGAKPTTSIFGNISAAKKESSEAKTSSSSTSLTSTMETSEYRESVADLNRSVIKFLQDQMGKSPYCILTPVFKNYDEHLKDLQDEESARTNSTKSKTAQARSQEPVAKVSRASSPPKAATTFTFGKPSAPIGASVSPLAKKPNCTITSGGTTTTTATPLVSFGSTASFTAPVPSSSSIFSLTAKPTGEAKSDDTPKSSIFSFGAKDTTTKKDEPNFSAPKTNGFSFGLKSNNDDKPSTSLFAGFGKAPGGAGDGAKGFSFTNSATPFSLGNIHPPAAAAAPAEEEKEEDTPPKVEFKQVVEDDAIYSKRCKVFIKKDKDFGDRGVGTLYLKPVKDSEKIQLLVRADTNLGNILVNLILSKGIPCQRMGKNNVLMVCVPTP-----EDSKATSLLLRVKTGDEADDLLEKIKEHIK-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .** * .:*...*** *:: ** *** *::: :*.*.:***:*: .. : ..*..*.*: . : . .** :. .. . . *.. : . .* * * * .. : .*.. : :. . *...:: ** ** .:: .::. .* * *.*:*::*:.:* :: : . . : : .. .. :. : . . *.** * :: . :*: .***. ..:. . : . . :. . . ::.: ** ..:: *.**:***:**:* *** :* ::*:***:** . .* **************:*:::. .:** * *****::****.* : : ...:*:****.::**:* . : :: ", "identical_positions": 109, "similar_positions": 151, "identity": "19.12%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1695", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BXL8-1", "uniprot_id": "CDCA4_HUMAN", "id": "Q9BXL8-1", "name": "Cell division cycle-associated protein 4", "aln": "--------------------------MFARGLKRKCVGH-EEDVEGALAGLKTVSSYSLQRQSLLDMSLVKLQLCHMLVEPNLCRSVLIANTVRQIQEEMTQDGTWRTVAP--QAAERAPLDRLVSTEILCRAAWG----------------QEGAHPAPGLGDGHTQGPVSDLCPVTSAQAPRHLQS------------------SAWEMDGPRENRGSFHKSLDQIFETLETKN-----PSCMEELFSDVDSPYYDLDTVLTGMMGGARPGPCEGLEGLAPATPGP----SSSCKSDLGELDHVVEILVET", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CWM2-1", "uniprot_id": "CDCA4_MOUSE", "id": "Q9CWM2-1", "name": "Cell division cycle-associated protein 4", "aln": "--------------------------MFARGLKRKYGDQ-EEGVEG----FGTVPSYSLQRQSLLDMSLVKLQLCHMLVEPNLCRSVLIANTVRQIQEEMSQDGVWHGMAP--QNVDRAPVERLVSTEILCRTVRG----------------AEEEHPAPELEDAPLQNSVSELPIVGSAPGQRNPQS------------------SLWEMDSPQENRGSFQKSLDQIFETLENKN-----SSSVEELFSDVDSSYYDLDTVLTGMMSGTKSSLCNGLEGFAAATPPP----SSTCKSDLAELDHVVEILVET", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2B7E4-1", "uniprot_id": "A0A8M2B7E4_DANRE", "id": "A0A8M2B7E4-1", "name": "", "aln": "MIRSLWMNFIHFPLRLLGCHPCFRLTMFSKGTKRKFADGGEEISDDGLVAARVASSYSLQRQSLLDMSLIKLQLCHMLVEPNLCRSVLIANTVRQIQEEMTHDGSWHMVTEAFCGASQSPSERLVATEVLCRSREPDAEPKLFSVISYEGCREEEVVADETLCSVSVSDTVSNVCLSG-RMGQRWEKSDVEREEEALEDSRLGSGDDDEEIDTEDESTPEGPKTIGQVFGTFEIKNGSPGPDSALEELFSDVDTSYYDLDTMLTGMQSAPKMGPYDLLDSLAPSHSSPSIVSTPNCRSDLNELDHIMEIIVGS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **::* *** . ** :. ...**************:******************************::** *: :: ..::* :***:**:***: * . * . ...**:: . * :* . *:* *. . *::.*:* *:* ** *.:********:.******:**** ...: . : *:.:*.: . * :..*:*** ****::**:* :", "identical_positions": 113, "similar_positions": 65, "identity": "36.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1697", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04143-1", "uniprot_id": "THRSP_RAT", "id": "P04143-1", "name": "Thyroid hormone-inducible hepatic protein", "aln": "-MQVLTKRYP-KNCLLK---VMDRYSAVVRNMEQVVMIPSLLRDVELS--------------GSGGSVQDG-------APDLYTYFTMLKSICVEVDH-------------------------------------------------GLLPREEWQAKVAGNEGSEAENEAAETEEAEEDRLSEE-----------------------------LDLEAQFHLHFSSLHHILTHLTQKAQEVTQKYQEMTG--QVL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62264-1", "uniprot_id": "THRSP_MOUSE", "id": "Q62264-1", "name": "Thyroid hormone-inducible hepatic protein", "aln": "-MQVLTKRYP-KNCLLT---VMDRYSAVVRNMEQVVMIPSLLRDVQLS--------------GPGGSVQDG-------APDLYTYFTMLKSICVEVDH-------------------------------------------------GLLPREEWQAKVAGNETSEAENDAAETEEAEEDRISEE-----------------------------LDLEAQFHLHFCSLHHILTHLTRKAQEVTRKYQEMTG--QVL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92748-1", "uniprot_id": "THRSP_HUMAN", "id": "Q92748-1", "name": "Thyroid hormone-inducible hepatic protein", "aln": "-MQVLTKRYP-KNCLLT---VMDRYAAEVHNMEQVVMIPSLLRDVQLS--------------GPGGQAQAE-------APDLYTYFTMLKAICVDVDH-------------------------------------------------GLLPREEWQAKVAGSE----ENGTAETEEVEDESASGE-----------------------------LDLEAQFHLHFSSLHHILMHLTEKAQEVTRKYQEMTG--QVW-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AWD1-1", "uniprot_id": "M1I1L_DANRE", "id": "Q8AWD1-1", "name": "Mid1-interacting protein 1-like", "aln": "MMQLSNDSHCNKHSLLN---VMNRFIAAANNMDETIMVPNLLRDVPLEDQESHASVSHNNNNNNEPSFPNK-------QRDMYEHYLLLKSIKNDMEW-------------------------------------------------GLLKR----EMAGGASFLEMAVKQEELPQMKGEAVEEG-----------------------------PDLEGQFHYHLHGLFSVLSKLTVQADHLTNRYKREIGGGSLLR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0X5-1", "uniprot_id": "Q9W0X5_DROME", "id": "Q9W0X5-1", "name": "Dentin sialophosphoprotein", "aln": "MEKFVKTVNIMDDTILVPCRLMDRQIGDSTDIIPATGKDSTANQLTQTS----------SAHGKRGAAHSKNVQDFLSASELFNLYNMLNSLKKDLLWTANQEDDDQQHSEQQLNASTSSTSSCNPSESKTEFNSGSPSTTASGSVKGHVRRTSTASMMSTNSVSNMSDSDSDISQENDSGLESDGNKSDNAQSSDGSDIVDVAKSKPGSGDKATELAKRCRRHLNGLYQCLEQMTEAANYLTARYQSDIG--PV--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . .. :* :*:* . :: . . .:: . ::: : :*::: :: * : * . . : : : . . :* : : *: .*. * ::* *: :* :*: * : ", "identical_positions": 15, "similar_positions": 48, "identity": "5.84%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1699", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51791-1", "uniprot_id": "CLCN3_MOUSE", "id": "P51791-1", "name": "H(+)/Cl(-) exchange transporter 3", "aln": "--------------------------MESEQLFHRGYYRNS-----------------YNSITSASSDEE-------------LLDGAGAIMDFQTSEDDNLLDGDTAAGTHYTMTNGGS-----------INSSTHLLDLLD------------EPIPGVGTYDDFHTIDWVREKCKDRERHRRINSKKKESAWEMTKSLYDAWSGWLVVTLTGLASGALAGLIDIAADWMTDLKEGICLSALWYNHEQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIR-GYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVACCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVS--YYFPLKTLWRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIRANIAWCRRRKSTKFGKYPVLEVIIVAAITAVIAFPNPYTRLNTSELIKELFTDCGPLESS-SLCDYRNDMNASKIVDDIPDRP--AGVGVYSAIWQLCLALIFKIIMTVFTFGIKVPSGLFIPSMAIGAIAGRIVGIAVEQLAYYHHDWFIFKEWCEVGADCITPGLYAMVGAAACLGGVTRMTVSLVVIVFELTGGLEYIVPLMAAVMTSKWVGDAFGREG-IYEAHIRLNGYPFLDAKEEFTHTTLAADVMRPRRSDPPLAVLTQDNMTVDDIENMINETS----YNGFPVIMSKE----SQRLVGFALRRDLTIAIESARKKQEGIVGSSRVCFAQHTPSLPAESPRPLKLRSILDMSPFTVTDHTPMEIVVDIFRKLGLRQCLVTHNGIVLGIITKKDILRHMAQTANQ----------------------------------DPASIMFN----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51792-1", "uniprot_id": "CLCN3_RAT", "id": "P51792-1", "name": "H(+)/Cl(-) exchange transporter 3", "aln": "--------------------------MESEQLFHRGYYRNS-----------------YNSITSASSDEE-------------LLDGAGAIMDFQTSEDDNLLDGDTAAGTHYTMTNGGS-----------INSSTHLLDLLD------------EPIPGVGTYDDFHTIDWVREKCKDRERHRRINSKKKESAWEMTKSLYDAWSGWLVVTLTGLASGALAGLIDIAADWMTDLKEGICLSALWYNHEQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIR-GYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVACCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVS--YYFPLKTLWRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIRANIAWCRRRKSTKFGKYPVLEVIIVAAITAVIAFPNPYTRLNTSELIKELFTDCGPLESS-SLCDYRNDMNASKIVDDIPDRP--AGVGVYSAIWQLCLALIFKIIMTVFTFGIKVPSGLFIPSMAIGAIAGRIVGIAVEQLAYYHHDWFIFKEWCEVGADCITPGLYAMVGAAACLGGVTRMTVSLVVIVFELTGGLEYIVPLMAAVMTSKWVGDAFGREG-IYEAHIRLNGYPFLDAKEEFTHTTLAADVMRPRRSDPPLAVLTQDNMTVDDIENMINETS----YNGFPVIMSKE----SQRLVGFALRRDLTIAIESARKKQEGVVGSSRVCFAQHTPSLPAESPRPLKLRSILDMSPFTVTDHTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDILRHMAQTANQ----------------------------------DPASIMFN----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51790-1", "uniprot_id": "CLCN3_HUMAN", "id": "P51790-1", "name": "H(+)/Cl(-) exchange transporter 3", "aln": "--------------------------MESEQLFHRGYYRNS-----------------YNSITSASSDEE-------------LLDGAGVIMDFQTSEDDNLLDGDTAVGTHYTMTNGGS-----------INSSTHLLDLLD------------EPIPGVGTYDDFHTIDWVREKCKDRERHRRINSKKKESAWEMTKSLYDAWSGWLVVTLTGLASGALAGLIDIAADWMTDLKEGICLSALWYNHEQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIR-GYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVACCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVS--YYFPLKTLWRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIRANIAWCRRRKSTKFGKYPVLEVIIVAAITAVIAFPNPYTRLNTSELIKELFTDCGPLESS-SLCDYRNDMNASKIVDDIPDRP--AGIGVYSAIWQLCLALIFKIIMTVFTFGIKVPSGLFIPSMAIGAIAGRIVGIAVEQLAYYHHDWFIFKEWCEVGADCITPGLYAMVGAAACLGGVTRMTVSLVVIVFELTGGLEYIVPLMAAVMTSKWVGDAFGREG-IYEAHIRLNGYPFLDAKEEFTHTTLAADVMRPRRNDPPLAVLTQDNMTVDDIENMINETS----YNGFPVIMSKE----SQRLVGFALRRDLTIAIESARKKQEGIVGSSRVCFAQHTPSLPAESPRPLKLRSILDMSPFTVTDHTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDILRHMAQTANQ----------------------------------DPASIMFN----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q887-1", "uniprot_id": "A0A8M9Q887_DANRE", "id": "A0A8M9Q887-1", "name": "Chloride channel protein", "aln": "--------------------------MESEQLFNRGYGRNS-----------------YNSITSASSDEE-------------LLDGAGVIMDFHTTEDDNLLDGDASPGSNYAMSNGGGGGG-------GASSSTHLLDLLE------------EPIPGVGTYDDFHTIDWVREKCKDRERHRKINSKKKESAWEFTKSLYDAWSGWLVVTLTGLASGALAGGIDIAADWMNDLKEGVCLSAMWFNHEQCCWGSNKTTFAERDKCPQWKTWAELILGQEQGPGSYIMNYFMFTFWALSFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIR-GYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVACCCGNIFSYLFPKYSKNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVS--YYFPLKTLWRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIRANIAWCRRRKSTRFGKYPVLEVITVAAITAIVAFPNPYTRQNTSELIKELFTDCGPLESS-QLCQYRSLMNGSQADPTGPDTASAATPGVYSAMWQLSLALVFKIIMTIFTFGLKVPSGLFIPSMAIGAIAGRIVGIAVEQLAYYHHDWFVFREWCEVGADCITPGLYAMVGAAACLGGVTRMTVSLVVIVFELTGGLEYIVPLMAAVMTSKWVGDAFGREG-IYEAHIRLNGYPFLDAKEEFTHTTLAREVMRPRRSDPPLAVLTQDDMTLAELQGIISETS----YNGFPVIVSKE----SQRLVGFALRRDITIAIENARRKQEGIVLNSRVYFTQHAPTLPADSPRPLKLRSILDMSPFTVTDHTPMEIVVDIFRKLGLRQCLVTHNGIVLGIITKKNILEHLEEIKQHVEPLTPPWYYYKKRYPPSYGPDGKPRPRVHNVQLAPSSSHYQEDEIEEEVRLLDNSSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUY1-1", "uniprot_id": "Q9VUY1_DROME", "id": "Q9VUY1-1", "name": "Chloride channel protein", "aln": "MEKFPLKGSREAAAEGNSYITAYQTVMKKSNGHTNGAGGDGDLDGTFRDHPLAQHTKLTTSLTAAGTDDEDMIDITPRSSPGDVIGGGGGGGSSSGYHRETATESDTERDFGHSGGNGGGNHHNQRTMHQHVPTHSAFGDPMDGALSFYGSSDVQDDIPGIGQYEDFHTIDWQRDIARDRMRHRYIVKKRQDSLWDLIKGSIDAGSGWLCVLLVGIAAGCVAGMVDIGASWMSDLKHGICPPAFWFNREQCCYPAKQSVFEEGN-CSTWKTWPEIFGLDRNGTGPYIVAYIWYVLWALLFASLSASLVRMFAPYACGSGIPEIKTILSGFIIR-GYLGKWTLLIKSVGLMLSVSAGLTLGKEGPMVHIASCIGNIFSHVFPKYGRNEAKKREILSAAAAAGVSVAFGAPIGGVLFSLEEVS--YYFPLKTLWRSFFCALIAAFVLRSLTPFGNEHSVLFFVEYNKPWIFFELIPFVFLGIMGGVIGTFFIKANLWWCRYRKFSKLGQYPVMEVLFVTLVTAIICYPNPFTRMNMNELIFLLVSKCSPGDVTNPLCDYKR-MNITSGNSFIEVTE--PGPGVYSSIWLLMLTFILKLALTIFTFGMKVPAGLFIPSLLLGAIMGRIVGIGVEQFAYSYPNIWFFTGECAD-SNLITPGLYAVVGAAAVLGGVTRMTVSLVVIMFELTGGVRYIVPLMAAAMASKWVGDALGRQG-IYDAHIALNGYPFLDSKEEFAHTTLAADVMQPKRNE-TLNVITQDSMTVDDVENLLKETE----HNGYPVVVSRE----NQYLVGFVLRRDLNLAIGNAKRLIEGISSSSIVLFTSSQP-IQNLGPQPLKLKKILDMAPITVTDQTPMETVVDMFRKLGLRQTLVTHNGRLLGVITKKDVLRHVKQMDNE----------------------------------DPNTVLFN----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P37020-1", "uniprot_id": "GEF1_YEAST", "id": "P37020-1", "name": "Anion/proton exchange transporter GEF1", "aln": "------------------------------------------------------------------------------------------MPTTYVPINQPIGDGEDVIDTNRFTN-----------------------------------------IPETQNFDQFVTIDKIAEENRPLSVDSDREFLN-SKYRHYREVIWDRAKTFITLSSTAIVIGCIAGFLQVFTETLVNWKTGHCQRNWLLNKSFCCNGVVNEVTSTSNLLLKRQEFECEAQGLWIAWKGHVSPFIIFMLLSVLFALISTLLVKYVAPMATGSGISEIKVWVSGFEYNKEFLGFLTLVIKSVALPLAISSGLSVGKEGPSVHYATCCGYLLTKWLLRDTLTYSSQYEYITAASGAGVAVAFGAPIGGVLFGLEEIASANRFNSSTLWKSYYVALVAITTLKYIDPFRNGRVILFNVTYDRDWKVQEIPIFIALGIFGGLYGKYISKWNINFIHFRK-MYLSSWPVQEVLFLATLTALISYFNEFLKLDMTESMGILFHECVKNDNTSTFSHRLCQLDENT-----------HAFEFLKIFTSLCFATVIRALLVVVSYGARVPAGIFVPSMAVGATFGRAVSLLVERFIS--------------GPSVITPGAYAFLGAAATLSGITNLTLTVVVIMFELTGAFMYIIPLMIVVAITRIILSTSGISGGIADQMIMVNGFPYLEDEQDEEEEETLEKYTAEQLMSSKLITIN-ETIYLSELESLLYDSASEYSVHGFPITKDEDKFEKEKRCIGYVLKRHLASKIMMQS--VNSTKAQTTLVYFNKSNEELGHRENCIGFKDIMNESPISVKKAVPVTLLFRMFKELGCKTIIVEESGILKGLVTAKDILRFKRIKYREVHG----------------------AKFTYNEALDRRCWSVIHFIIKRFTTNRNGNVI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.: . ** :::* *** : : . . .. . : * . :: : ..:. *.:** ::: :. : : * * * *:. ** : . : : : . :: :: : : :: ** ::. **: .** * ****.***. :*** . :** **:**:: * *::::**::***** ** * * * ::: : : . :.: * ::**:.***:************.***:: * .***:*:: **:* .*: : ** * : :** * *. * . *: *: **::**: * :: : *: : : ** :..:** **: :: :**::.: * : : : .* : *. .* : : :.. :: . . . : * :: ::: :.:.::* :**:*:*:**: :** ** *.: **:: .. **** **.:**** *.*:*.:*:::***:*****.. **:*** .. :: : .: * .* * : * :**:*:*: ::: . . : . * .:. : : : :::.:: :: :*:*: ..: .: :*:.*:*.: * :. .: : : . . : ::.*:: :*::*.. .*: :. :*::** : :* ..* : *::* *::*.. .. ", "identical_positions": 181, "similar_positions": 261, "identity": "18.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1704", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NUA8-1", "uniprot_id": "ZBT40_HUMAN", "id": "Q9NUA8-1", "name": "Zinc finger and BTB domain-containing protein 40", "aln": "MELPNYSRQLLQQLYTLCKEQQFCDCTISIGTIYFRAHKLVLAAASLLFKTLLDNTDTISIDASVVSPEEFALLLEMMYTGKLPVGKHNFSKIISLADSLQMFDVAVSCKNLLTSLVNCSVQGQVVRDVSAPSSETFRKEPEKPQVEILSSEGAGEPHSSPELAATPGGPVKAETEEAAHSVSQEMSVNSPTAQESQRNAETPAETPTTAEACSPSPAVQTFSEAKKTSTEPGCERKHYQLNFLLENEGVFSDALMVTQDVLKKLEMCSEIKGPQKEMIVKCFEGE-GGHSAFQRILGKVREE-SLDVQTVVSLLRLYQYSNPAVKTALLDRKPEDVDTVQPKGSTEEGKTLSVLLLEHKEDLIQCVTQLRPIMESLETAKEEFLTGTEKRVILNCCEGRTPKETIENLLHRMTEEKTLTAEGLVKLLQAVKTTFPNLGLLLEKLQKSATLPSTT---------------------------VQPSPDDYGTELLRRYHENLSEIFTDNQILLKMISHMTSLAPGEREVMEKLVKRDSGSGGFNSLISAVLEKQTLSATAIWQLLLVVQETKTCPLDLLMEEIRREPGADAFFRAVTTPEHATLETILRHNQLILEAIQQKIEYKLFTSEEEHLAETVKEILSIPSETASPEASLRAVLSRAMEK-SVPAIEICHLLCSVHKSFPGLQPVMQELAYIGVLTKEDGEKETWKVSNKFHLEANNKEDE--KAAKEDSQPGEQNDQGETGSLPGQQEKEASASPDPAKKSFICKACDKSFHFYCRLKVHMKRCRVAKSKQVQCKECSETKDSKKELDKHQLEAHGAGGEPDAPKKKKKRLPVTCDLCGREFAHASGMQYHKLTEHFDEKPFSCEECGAKFAANSTLKNHLRLHTGDRPFMCKHCLMTFTQASALAYHTKKKHSEGKMYACQYCDAVFAQSIELSRHVRTHTGDKPYVCRDCGKGFRQANGLSIHLHTFHN-IEDPYDCKKCRMSFPTLQDHRKHIHEVHSKEYHPCPTCGKIFSAPSMLERHVVTHVGGKPFSCGICNKAYQQLSGLWYHNRTHHPDVFAAQNHRSSKFSSLQCSSCDKTFPNTIEHKKHIKAEHADMKFHECDQCKELFPTPALLQVHVKCQHSGSQPFRCLYCAATFRFPGALQHHVTTEHFKQSETTFPCELCGELFTSQAQLDSHLESEHPKVMSTETQAAASQMAQVIQTPEPVAP-TEQVITLEETQLAGS-QVFVTLPDSQASQASSELVAVTVEDLLDGTVTLICGEAK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A365-1", "uniprot_id": "D4A365_RAT", "id": "D4A365-1", "name": "", "aln": "MELPNYSQQLLLQLYALCKEQRFCDCTISIGNIYFRAHKPVLAAASLLFKTLLDSTDAISIDASVVSPEEFALLLEMTYTGKLPVGKHNFSKIISLADSLQMFDVAVCCKNLLTNLVNCSVQGQVVRDISVLSSEAGGKESEKPQVEVLSSEGAGEPSSSLEVSAMPAGTEKAKTQEVIHMVTQEISADPPIAQEVQVAAEITGATPHTTEVCSPLPAGQIPSEAKAASTEAGCERKQDQLTLLLEYESVFSSAALLTPDMLRRLEGCSEIEGPQKETVMECLEAE-GGGSAFQRILDKVHDG-SLDVQVALSLMRLCQESTPAEKVS------------QIEGSAGEGKTLSVLLLEHKEDLIQCVTQLRPIVEFLETAKEEFLPDSEKRVIQICCEGRTPKETVENLLHRVTEEKTLPAKSLVKLLQAVRTAFPNLGLLLENLQKVAESPGTTGLTRATRETAWTEEPKRLCIPADRVDGSSPNPDAYGAELLRKYHENLSEILIDSQVLLKVISRLKSLAPGDREVMQTLVKQDSGSGGVSSLMSAALERQTVSAAAIWQLLLAAQETETCPLNLLLEEVEREPGAGAFFRAVTAPESTVLETILRHSKLVREAIQQTVGREHLSSEEEHLAETVKEMLSISSETVSPEASLRVVLSRAMEK-SVSASVVCHLLCSVHRSFPGLQPLMQELAHVGFLTKEN-AEERWKVTDGLHPGAKDKTEEAAEAAREDGRAMEQKEQGPE-PVPERQEKDTSASPDAAKKSFVCKACDKSFHFYCRLKVHMKRCRVAKSKQAQGKGDSDTRDSEKELGRQQPEARSAGAEPDAPKKKKKRLPVTCDLCGREFAHASGMQYHKLTEHFDEKPFSCEECGAKFAANSTLKNHLRLHTGDRPFMCKHCLMTFTQASALAYHTKKKHSEGKMYACQYCDAVFAQSIELSRHVRTHTGDKPYVCRDCGKGFRQANGLSIHLHTFHTDIEDPYDCKKCRMSFSTLQDHRKHIHDVHSKEYHPCPTCGKIFSAPSMLERHMVTHVGGKPFSCGICNKAYQQLSGLWYHNRTHHPDVFAAQNHRSPKFSSLQCSSCDKTFSNTIEHKKHIKTEHADLKFHECGQCKELFPTPALLQVHVKCQHSGSQPFRCLYCAATFRFPGALQHHVTTEHFKQSESTFPCELCGELFTSQAQLDGHLESEHPKVTGTETQAAASRMVQVIQAPEPAAP-AEQVITLEETQLAGS-QVFVTLPDPQTSQNSSELVAVTVEDLLDGTVTLICGEAK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AC58GTM5-1", "uniprot_id": "A0AC58GTM5_DANRE", "id": "A0AC58GTM5-1", "name": "", "aln": "--MRAKALQILEHMRSMSSER---------PQIFTRMRTIKMFCG----RIFISQRNVVLRRSLNKEPDHLNLKVQNGAAKLQPTAHAAASHFTKREKVLRLLHPDLLSSQEFSSLLDLVYTGKLP---------------------------PGKHNLTRLIAAADSLQMFDVAVGCKNILTDLMKQTEPIDPQVIKPDSVVEQVKREERNLQEDNAVEMISHDRAG----------------------LMKILQRGKSHVQFLEAWDAVSTEERQVILEMFRGDPSADELYQRLLNLLEVERVLSSKTVLTLLEQLKHSDLEEQGD------------QSCSQPKDTVQGSSGILERLSEVTHHLSSVNNLSEILTSAVTKCTNQVEKEALLQCCSAPSSAEVLENLLCKLREMS-ISEETFLILLNEVKEKSTDLLQLLETLENTRG---------------------------------VTTKESNAVDLLGMYQSRLVKLNLDLQLIKQSLQMGPEMPENDRQCIEGLLVEKADAEVFERLILAALDGSLQAVTAWR--ILFWTETHNPELQILMQELKEKPEAQKLLQTIKD-----IDVLFKHKSLILETISDFTVLEQGLNAMDHETEKVTEFLQSCRRADGELESVLQTVDRVLSRDSGFASPLCQLMCANLKSFPQLSPLKQTAGLVSDSECPG------------------------KAEVEQGGSAVDSEDEDD------EDCSSTGRRKPVLVSYSCDWCRKTFDFKCRLIKHRKGCALAPGKEQRCGECSMAFPTLKSLHQHCVETHGG-----PPAKKKKTEHVACDMCDKTFKHSSGLLYHKRTEHFEERPYACEECGAKFAATSSLKNHMRLHTGEKPFHCKHCDMSFSVAAALSYHTKKKHAEGKMYCCQYCSSSFAQSIELTRHVRTHTGDKPYVCRECGKGFKQANGLSVHLQNFHN-ITEPHDCQKCRVSFSSLDELRQHIQEVHPKELHQCPECSKIYNSEGALEKHMNVHDGNKPYSCKTCNKAYQTLSGLWYHNRTVHPEISTSQSNRS-LKALLQCERCDKSFTSHNSLIKHQITNHTDVHVWKCVSCDCSLSSEQELQHHVCSVQTP--------------------------------ALFSCMVCSLHFPSEPDFQQHFLSKHLQLVQDEAQTQSSASQTVVQCEAAADPAVEQVINLHQSQSESSQQVFVALADQQETPAGSGMVAVSMEDLLNGTVTLICEQSQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *:* :: ::..*: *: * :. : .. : ::.. :.: : .*:.: * :: : *..: *:: . . *:::. : ..: ::.*:: *:: .*: : ::* . : : ::: :. * : . . . . * : *. : : . . :: ** . :. ::: ::: :..: .. . :**:*. :. *. :..::*:. : * : * ... : * :**: .:: : ::.:. : * * :* : **..: **.. :. *.:**** :: * . :. : :: **: *: .:* ***.*:: .. : ..:** *:..* :: * *:: : :. .:. .:*: :: *: ..:.: .. *: *.*: . :.:* :* **.. *::*::*:..:* * :::::. ::.:::*..*: *:*.: : . :* :*.*.*:*. .: . *: .:.*.:.: * * :*:*:*: :*** *.*: * . :. . :* *:. . :.:: :: .::. ... *: *. * *:*.* *** * * * :* .*: : * : : *.* :: *::.. .* **** *:**:*.: * *:**: *** ****:*:*::**********.*:****:*****::** **** *:*: *:**:*******:*****.****.: *******:***************:*****:******:**:.**. * :*:**:***:**.:*:: *:**::**.** * ** *.**:.: . **:*: .* *.**:** ****** ********** **:: ::*.:** : ***. ***:*.. . ** ::*:*::. :* .*. :.: ** ** . :: : *.* :*. *.*:.::: *: *:* :: *:*: :* *:* .. * .****.*.::* .* ****:*.* * : .* :***::****:******* :::", "identical_positions": 331, "similar_positions": 402, "identity": "25.98%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1717", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O00472-1", "uniprot_id": "ELL2_HUMAN", "id": "O00472-1", "name": "RNA polymerase II elongation factor ELL2", "aln": "MAAGGTGGLREEQRYGLSCGRLGQDNITVLHVKLTETAIRALETYQSHKNLIPFRPSIQFQGLHGLVKIPKNDPLNEVHNFNFYLSNVGKDNPQGSFDCIQQTFSSSGASQLNCLGFIQDKITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAVSDTVPERKRSTPMNPANTIRKTHSSSTISQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKNSLGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRSLESVLSRKLNPSQNAAGTSRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGHLNPTSEKSAAGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDSIYE------------DQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKS---------KKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPNS-----SGGVKEDCTASMEP-SAIEL----------------PDYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEYQNVHEEVLQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UKU1-1", "uniprot_id": "ELL2_MOUSE", "id": "Q3UKU1-1", "name": "RNA polymerase II elongation factor ELL2", "aln": "MAAGGAAGLREEQRYGLACGRLGQDNITVLHVKLTETAIRALETYQSHKNLIPFRPSIQFQGLQGLMKIPKNDPFNEVQNFNFYLSNVGRDNPQGSFDCIQQTLSSSGASQLNCLGFIQDKITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAISDTVPERKRSTPMNPANTIRKMHSGNSVSQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKNSLGAILQQVANLNPKDLSYTLKDYVFKELQRDWPGYSETDRQTLDLVLSRKLNPSQNAS-TSRSESPLCSSKDAASSPQKRPLDSDFIDPLMNKKARISHLTNRVPPTLNGYLNPTSEKSCAGLLPPPAAAAIPTLSPLPSTHLPVSNPPQTVNSNSNSPSTPEGLGTQDLPVDSFSQNGSIFE------------DQQEKYTSRTCLETLPPSSALLKCPKPMEEEHPVSHKKS---------KKKSKKHKEKDQIKKLDIETMEEKEEDLQREE-TAKLSNASPNP-----NEGVKEGCTASMEPSSALEL----------------PDYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEYQNVHEEVLQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1R2K7-1", "uniprot_id": "F1R2K7_DANRE", "id": "F1R2K7-1", "name": "", "aln": "----MMAALCEDGTYGLNCGRK-SDKISVLHVKLTESAFKALESYQNCKNAPSTQATIRFQGLQGRIKIPTTEASDGSHNFNFYLSNFGKDNPQGSFECIHQYISSSGIPHLSSLGTIQDKITVCATNDSYQVTKERVTKAEEDKSKNSTKFIKPGGPFRDKKIHRKPAPSAP-DPVPERKQTTPLNPANTIRKCLTNNPVSQKPYRDRVIHLLALRSYKKLEVLARLQRDGVSQKDRNSLGTTLHQVANLNPKDNSYSLKDFIFREVQRDWPGYTEDDRVQVDRILARKLG--LNLESVSSN-----SPTKEPTSPLKRQPETDFIDPLMPKKPRISHLSNRGPPSSSRHPSETEDK----KPAPTVACPGPSFP-----------PPPVTGSSSNSPSTPEGLGSQDLPLDQSSICGNSSESYAPRSQTPSPPNQPASTTSPSSFSTCTVSTTTITSTTTTSGSHQVSSAASPTDDSGSKKPKKSKKHKDKEKKREGEREKEKDRERKRDREHRKEDLADKDAQPRKKHRSEAEQKHIPANISHDSDREAGKEKPVNSTELPAPTKPDYISKYTAVISMDQRQHYKDDFNGEYDEYRILHARVESVTRRFTKLDAQCRRLAPGTKEYQEVHEQVLQEYKKIKQHSPNYYEEKQRCEYLHNKLAHIKRLIADFDQRRAQSWL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..* *: *** *** .*:*:********:*::***:**. ** . :.:*:****:* :***..:. : :********.*:*******:**:* :**** .:*..** ***************:*:**:*:***:. :.***.******: .*::: : **.* *.*****::**:******** :...:**:************::*** *:*****:***.***:****: *:******.** **:***::*:*:*******:* ** :: :*:***. * .* . *. . :** ** :::****** **.*****:** **: . : . *.:* *..*.. *: . ** ..*.********* *:****:*. * .. * :* . ** :.:.* . .:. :..... . .* :* * *******:*:: :: : *. :::*.. .**. .* : ..:. . . :: .*.:. * * ***: ** *::* :***:******.****** ****:*:*:*** ***** :**:**:****:***:*****:**** ****:*** ****************.:***::*:** ", "identical_positions": 332, "similar_positions": 177, "identity": "48.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1723", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K1K5-1", "uniprot_id": "A0A0G2K1K5_RAT", "id": "A0A0G2K1K5-1", "name": "Trafficking protein particle complex subunit 11", "aln": "MSPTQWDFPVELCCRPMAFVTLTGLDVVYNAVHRAVWDAFCANRR---ADRVPISFKVLPGDHEYPKCRSKRTSYEWYIPKGILKTGWMNKHLNLVPALVVVFYELDWDEPQWKEKQSECATRVEIVRQSLQGRNTKVAVVLIQKKTPLPPGEDIIASERAAALCNVCELSGKSLFVLPHTDHLVGYIIRLENAFYEHAQTYYYTEIRRVKSHKEFLNKTTHQLLFVRHQFKIAFFSELKQDTQNALKNYRTAYNLVHELRAHETNILEIKTMAGFINYKICRLCFQHNTPLDAIAQFRKHIDLCKKKIGSAELSFEHAAWMSKQFQAFGDLFDEAIKLGLTAIQTQNPGFYYQQAAYYAQERKQHAKALCNHDAAVVYPSPDPLETPTGVLDFYGQRPWRQGILSFDLSDPEKEKAGILAIQLKERSVVHSEMIITLLSNAVAQFKKYKCPRMKSHLMVQMGEEYYYAKDYTKALKLLDYVMCDYRSEAWWTLLTSILTTALKCSYLMAQLKDYITYSLELLGRASTLKDDQKSRIEKNLMNVLMNESPDPEPDCDALAVKTAQKLWADRVSLAGSNVFTIGVQDFVPFVQCKAKFHAPSFHVDVPVQFDVYLKADCPHPIRFSKLCVSFNNQGYNQFCVLEEASK----------------ASEVLENLTQG------KMCLVPGKTRKLLFKFVAKTEDVGKKIEITSVDLFLGSESGRCVVLSWQ-------------GGGGDAASSQEALQAARSFKRRPKLPDDEVHWDSIIVQASTMIISRVPNISVHLRHEPPALMNEMYCLVVTVQSQEKSQIRDVKLTAGLKPGQDANLTQKTHVTLHGAELCDESYPALLTDIPVGDLNPGEQLEKTVYVRCGTVG----SRMFLVYVSYLINTTVEGK------------------GIMCKCHKDETVTIETVFPFDVAVRFVSTKFEHLERVYADIPFLLMT------------------------------------------------------------------------------------------------------------DILSASPWALTIVSSELQLAPSMAAMDH---------LESQIDKVVLQTGESASECFCLRCPSAGNLEGG--------------------VATGHYIISWKRSSGMENIPAISTIITLPHVIVENIPLHVNADLPSFGRVRESLPVRYHLQNKTDLVQDVEISVEPSDAFMFSGLKQIRLRILPGTKQEMLYNFYPLMAGYQQLPSLNINLLRFPN---------FTNQLLRRFIPTSIFVKPQGRLLEDTSIAAA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RXC1-1", "uniprot_id": "TPC11_MOUSE", "id": "B2RXC1-1", "name": "Trafficking protein particle complex subunit 11", "aln": "MSPTQWDFPVELCCRPMAFVTLTGLDVVYNAVHRAVWDAFCANRR---ADRVPISFKVLPGDHEYPKCRSKRTSYEWYIPKGVLKTGWMNKHLNLVPALVVVFYELDWDEPQWKEKQSECATRVEIVRQSLQGRNTKVAVVLIQKKTPLPPGEDVIASERAAALCNVCELSGKSLFVLPHTDHLVGYIIRLENAFYEHAQTYYYTEIRRVKSHKEFLNKTTHQLLFVRHQFKIAFFSELKQDTQNALKNYRIAYNLVHELRAHETNILEIKTMAGFINYKICRLCFQHNTPLDAIAQFRKHIDLCKKKIGSAELAFEHAAWMAKQFQAFGDLFDEAIKLGLTAIQTQNPGFYYQQAAYYAQERKQHAKALCNHDAAVMYPNPDPLETQSGVLDFYGQRPWRQGILSFDLSDPEKEKAGILAIQLKERSVVHSEIIIALLSNAVAQFKKYKCPRMKSHLMVQMGEEYYYAKDYTKALKLLDYVMCDYRSEAWWTLLTSILTTALKCSYLMAQLKDYITYSLELLGRASTLKDEQKSRIEKNLMNVLMNESPDPEPDCDVLAVKTAQKLWADRVSLAGSNVFQIGVQDFVPFVQCKAKFHAPSFHVDVPVEFDVFLKADCPHPIRFSKLCVSFNNQVYNQFCVLEEASK----------------ASEVLENLTQG------KMCLVPGKTRKLSFKFVAKTEDVGKKIEITSVDLFLGSESGRCVVLSWQ-------------GGGGDAASSQEALQAARSFKRRPKLAEDEIHWDSVIIQASTMIISRVPNISVHLRHEPPALMNEMYCLVVTVQSHEKSPIRDVKLTAGLKPGQDANLTQKTHVTLHGAELCDESYPALLTDIPVGDLHPGEQLEKTVYVRCGTVG----SRMFLVYVSYLINTTVEGK------------------EIICKCHKDDTVTIETVFPFDVAVRFVSTKFEHLERVYADIPFLLMT------------------------------------------------------------------------------------------------------------DVLSASPWALTIVSSELQLAPSMTAMDH---------LESQIDKVVLQTGESASECFCLRCPSAGNIEGG--------------------VATGHYIISWKRASVVESIPAVSTVITLPHVIAENIPLHVNADLPSFGRVRESLPVRYHLQNKTDLVQDVEISVEPSDAFMFSGLKQIRLRILPGTKQEMLYNFYPLMAGYQQLPSLNINLLRFPN---------FTNQLLRRFIPTSIFVKPQGRLLEDTSIAAA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z392-1", "uniprot_id": "TPC11_HUMAN", "id": "Q7Z392-1", "name": "Trafficking protein particle complex subunit 11", "aln": "MSPTQWDFPVELCCRPMAFVTLTGLDVVYNAVHRAVWDAFCANRR---ADRVPISFKVLPGDHEYPKCRPKRTSYEWYIPKGILKTGWMNKHLNLVPALVVVFYELDWDEPQWKEKQSECATRVEIVRQSLQGRNTKVAVVLIQKKTPLPPGEDVIASERAAALCNACELSGKSLFVLPHTDHLVGYIIRLENAFYEHAQTYYYTEIRRVKSHKEFLNKTTHQLLFVRHQFKIAFFSELKQDTQNALKNYRTAYNLVHELRAHETNILEIKTMAGFINYKICRLCFQHNTPLDAIAQFRKHIDLCKKKIGSAELSFEHDAWMSKQFQAFGDLFDEAIKLGLTAIQTQNPGFYYQQAAYYAQERKQLAKTLCNHEASVMYPNPDPLETQTGVLDFYGQRSWRQGILSFDLSDPEKEKVGILAIQLKERNVVHSEIIITLLSNAVAQFKKYKCPRMKSHLMVQMGEEYYYAKDYTKALKLLDYVMCDYRSEGWWTLLTSVLTTALKCSYLMAQLKDYITYSLELLGRASTLKDDQKSRIEKNLINVLMNESPDPEPDCDILAVKTAQKLWADRISLAGSNIFTIGVQDFVPFVQCKAKFHAPSFHVDVPVQFDIYLKADCPHPIRFSKLCVSFNNQEYNQFCVIEEASK----------------ANEVLENLTQG------KMCLVPGKTRKLLFKFVAKTEDVGKKIEITSVDLALGNETGRCVVLNWQ-------------GGGGDAASSQEALQAARSFKRRPKLPDNEVHWDSIIIQASTMIISRVPNISVHLLHEPPALTNEMYCLVVTVQSHEKTQIRDVKLTAGLKPGQDANLTQKTHVTLHGTELCDESYPALLTDIPVGDLHPGEQLEKMLYVRCGTVG----SRMFLVYVSYLINTTVEEK------------------EIVCKCHKDETVTIETVFPFDVAVKFVSTKFEHLERVYADIPFLLMT------------------------------------------------------------------------------------------------------------DLLSASPWALTIVSSELQLAPSMTTVDQ---------LESQVDNVILQTGESASECFCLQCPSLGNIEGG--------------------VATGHYIISWKRTSAMENIPIITTVITLPHVIVENIPLHVNADLPSFGRVRESLPVKYHLQNKTDLVQDVEISVEPSDAFMFSGLKQIRLRILPGTEQEMLYNFYPLMAGYQQLPSLNINLLRFPN---------FTNQLLRRFIPTSIFVKPQGRLMDDTSIAAA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1RLX4-1", "uniprot_id": "TPC11_DANRE", "id": "Q1RLX4-1", "name": "Trafficking protein particle complex subunit 11", "aln": "MSPARWDLPPELCCRPMAFVALTGLDVVYNAIHRAIWDAFCANRR---ADRVPISFKVLPGDHEYPKCRTKRTSYEWYIPKGILKTGWMNKHLNLVPALVVLFYELDWDDPQWKEKQSECATKVEIVRTSLQGRNTKVAVVLIQKKTPLPPGEDLVASERASALCGACDLSGKSLFVLPHTDHLVGYIIRLENAFYEHAQTYYYNEIRRVKSHKEFLNKTTHQLLFVRHQFKMGFFSELKQDTQNALKYYRTAYSLVHELRAHETNVLEIKTMAGFINYKICRLCFQHNTPLDAIAQFRKHIDLCKKKIGSAELAFEHTAWMSKQFQSFGDLFDEAIKLGLTAIQTQNPGFYYQQAAYYAQERKQQAGQLCSHEPGVGYPAPDPLETTSGALDFYGQRPWRQGHQSIDPPDSEKEKQGILALQVKERDVLHSELIIALLSNAVAQFKKYKCPRMKSHLMVQMGEEYYHAKDYTKALKLLDYVMCDYRTERWWSLLTSIVCTALKCSYLMGQVKDYITYSMELVGRASILSEEQKSRIEKNLIKVLMNEVPEPEPDCDPVSVKAAQSLWSDRVSLAGNNEFTIDVQDYVPFVQCKAKFLSPSFHIDEPVQLHVYVRADCPHPVRFSKLCVSLSNQEYNQYCLLEDAYK----------------GKDILEPSSQE------NMCLVPGKTRKYCFNFVAKTEDVGKKIEITSVGLMLGRETGRYVYLNWR-------------GGWGDAASSHESLQASRSFKRRTRLPEQHVDWDAVSVQSSTMIISRVPKISVQLTHEPPALTNEMFCMTVTIKSEEDTVGKDIKLTAGLKPGQDANLTQSTQITLNGSEVCDDSHPALLPDIPLGDLQPGQKIVKPLYIRCVSTG----SRIFLFHVAYSVSATVEGK------------------DITCKCHKDETVTVETVVPFEVAMKFVSSKFEHLERVYVDIPFLLMM------------------------------------------------------------------------------------------------------------DILSASPWPIELVESEVQLASSMTAIDQ---------PQSQVEGVTLQTSECASECFLLKCPPVQNGTST--------------------VASGHYIISWKRKSTFTETSVVRTVITLPHVMVENIPLYVHAEVPSFGRVRESLPVRYHLENRTGLVQDVEISVEPSDAFMFSGLKQVRMRILPGAEQEMLYNFYPLMAGYQVLPQLNINLLRFPN---------ISSQLLRRFLPSRIFVKPQGR-NGDASIEAA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IRE3-1", "uniprot_id": "Q8IRE3_DROME", "id": "Q8IRE3-1", "name": "Trafficking protein particle complex subunit 11", "aln": "MTMDATALPSELLVTPQPLVGFCGLDTARVSVHKAVWEAFSGSLQRKAADRAAVQYKLLPPNYEFPVAKPKRASYEWYHPKGILKRNWMLKHLHVLPSVVVLFQDMEWNDLQWTEKQVQCAAIVQALKNTLQERNTRLCLVLLQRAAPLPPGEDLLAAERAASLTNACGITSKMLFILPHTEHLTGYALRLESAFLDMAQSYYALMSKRIRNHRDQLT-AAHTSLKIRHQFKLGFVAEMRQDFSTGQKHYFQAYANLDEIRINDGNCLEIKTLAGFLNYKICRLMFKLKTPRDAINQFIIHVEKHKSRVGFKDLAFEHHAWLSTQHSVFAELFCEAIKNGLPALQTQHPGIYYHKAAEFVMKRRDAAMEAYAAMQASSEATPTPIQNPLSLYTEFFG------IRAVKTGDLVAEQQANMQLCDQERSYNHSAAIIALLSQAMAQFKIYKCLRFRKKLAIDMAEEYLKSGDHAKALTLYSLMLPDYRQEKWTTIFTDVLLKTLRCALLSGSVADYIACSVEALSLRHQSDQSERILILENLWQVFQGVPPMP----KTQLTPEAQALWTSALANVKSP-IQIDLDKVNDVVEMCATFERVQLSNDDLLQLQLIVRVLTDIPLRIRSFHVILADAGNPQNSYKLEALKYFCFPTLTQLRGQKQPDDEQLENPSQEPKNFEKNMRLEPGSYYQLFCSTEAQQFHENTQLRIVRLEAHMGTDQVAALLTCSSNYSRQLFRHHTRSRDLDDNVTINPICYIAPTFHLDTQTNLGHGHDNGLTDDKEMVATKMLVNEYFPVVTTVSNPYNVYLQNVGVHISIPVGLRNSVFLTTDISPGRQKLHSQIQIDVGELSAHGSNTATFYIFSLTEAEIKLAQRLSYTLDVDRGPGGGGSNARVSTAPNSSESTPDHEVKSVIPSVAAISPVQIEYLDETRLRKSREDTLTVRCYGDFKFNARFYTMDRKPLNQVYRGENFLLRANTEVVAVDDVEILDSFFICDHNLVQSNYSFKQKKYTNKYSAGEQLESVIVLRTNATLRDWATARDLDHRGKLEGKAVASKFIRPVPKPSSEEPLAPTPPAGISAYMSKSLVTKIPTTMTIINSNSAVSNALQVANAGVMSNSTQSDDVNVAEEAINTHEGIKTTRLIYNKALEAVQGTGHCRGFIKKIYTLEGNPSAVPIFGVFCIRWRRAN-CKEENESKFVIRGLDIAEPPLNIYCTIEEKMFVKMPMAFKVVLKNPTTHVLHLIANLSISKTDNFICSGHKQLDISIMAYEEKELVYNLYPLQVGWQELPVLSLEYNTKADPQKKDSQNALLDELVQRALPKRVFVLPPLKQQNK------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :* ** * .:* : ***.. ::*:*:*:**... : ***..:.:*:** ::*:* .:.**:***** ***:** .** ***:::*::**:* :::*:: **.*** :**: *: :: :** ***::.:**:*: :*******::*:***::* ..* ::.* **:****:**.** :***.** : **:** :*::.*:: *. ::* * :*****:.*.:*::** ... * * ** :.*:* :: * *****:***:******* *: :** *** ** *:: *.::* :*:*** **::.*.. *.:** **** **.*:***:**:**::** :. :*:: * . . * *::. . : :.. * *: . : : :**. ** **:***:*:**** *** *::.:* ::*.*** : *::***.* . :: *** * * :::*.:: .:*:*: * ..: ***: *:* :. .:.:: * :** :*: . * * . . ** **:. :: . . : *.::. .*: *.* .: * :::.: ::. *:*: .: * : : * . :* * .: ** :* :* * **. : . *: . ..::.*. : :* : : . .* .: : : :*: .: . . :.: : . : . : : . : . * . . * ..: **:.:.**:: :* . . : .:: . : .:. .::: .::: : : . * :*: : .. * * : :::*:*:. *.. :* : . : *::** . *** .::: * .: ::.*: :: :: . : : :: ::* * . : . . * : * *:* . . :* .: : :: : * :: :: * : . * .::*:. :* *: ** **: : *:. ::*::**:*** .*:* ** *.:: .: : .:*::* :*. :** * : . ", "identical_positions": 305, "similar_positions": 392, "identity": "22.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1725", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P30414-1", "uniprot_id": "NKTR_HUMAN", "id": "P30414-1", "name": "NK-tumor recognition protein", "aln": "MGAQDRPQCHFDIEINREPVGRIMFQLFSDICPKTCKNFLCLCSGEKGLGKTTGKKLCYKGSTFHRVVKNFMIQGGDFSEGNGKGGESIYGGYFKDENFILKHDRAFLLSMANRGKHTNGSQFFITTKPAPHLDGVHVVFGLVISGFEVIEQIENLKTDAASRPYADVRVIDCGVLATKSIKDVFEKKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDD-DSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHS-GHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDS-----YRSKSHSQSYSRGSSRSRTASKSS--------SHSRSRSKSRSSSKSGHRK---RASKSPRKTASQLSENKPVKTEPLRATMA----------QNENVVVQP-VVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRS--LASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEK-KVSENNETIKDNILKTEKSSEEDLSGKHDTVTVSSDLDQFTKDDSKLSISPTALNTEENVACLQN-IQHVEESVPNGVEDVLQTDDNMEICTPDRSSPAKVEETSPLGNARLDTPDINIVLKQDMATEHPQAEVVKQESSMSESKVLGEVGKQDSSSASLASAGESTGKKE--VAEKSQINLIDKKWKPLQGVGNLAAPNAATSSAVEVKVLTTVPEMKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQ-TPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSESSRYS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P30415-1", "uniprot_id": "NKTR_MOUSE", "id": "P30415-1", "name": "NK-tumor recognition protein", "aln": "MGAQDRPQCHFDIEINREPVGRIMFQLFSDICPKTCKNFLCLCSGEKGLGKTTGKKLCYKGSTFHRVVKNFMIQGGDFSEGNGKGGESIYGGYFKDENFILKHDRAFLLSMANRGKHTNGSQFFITTKPAPHLDGVHVVFGLVISGFEVIEQIENLKTDAASRPYADVRVIDCGVLATKLTKDVFEKKRKKPTCSEGSDSSSRSSSSSESSSESEVERETIRRRRHKRRPKVRHAKKRRKEMSSSEEPRRKRTVSPEGYSERSDVNEKRSVDSNTKREKPVVRPEEIPPVPENRFLLRRDMPAITVEPEQNIPDVAPVVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSHSESKDD-DSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSDGHHKKHRKEKKFKHKKKAKKQKHCRRHRQTKKRRIVMP-DLEPSRSPTHRMKSSCVRERRSRASSSSSHHSSKRDWSKSDQDDGSASTHSSRDS-----YRSKSHSRSDSRGSSRSRAVSKSS--------SRSLNRSKSRSSSRSGPR----RTSISPKK-PAQLSENKPVKTEPLRPSVP----------QNGNVLVQP-VAAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPVQSTYSLTNIKATVSSSSYHKREKPSESDGSAYSKYSDRSSGSSGRSGSKSSRSRSSSRSYTRSRSRSLPTSRSLSRSPSSRSHSPNKYSDGSQHSRSSSYTSVSSDDGRRAM--FRSNRKKSVTSHKRHRSNSEKTLHSKYVRGREKSSRHRKYSESRSSLDYSSDSDQSHVQVYS-APEKEKQGKVEALNDKQGKGREEGKPKPEWECPRSKKRTPKD----HSRDDSVSKGKNCAGSKWDSESNSEQDVTKSRKSDPRRGSEKEEGEASSDSESEVGQSHIKAKPPAKPPTSTFLPGSDGAWKSRRPQSSASESESSCSNLGNIRGEPQKQKH-SKDDLKGDHTKRAREKSKAKKDKKHKAPKRKQAFHWQPPLEFGDDEEEEMNGKQVTQDPKEKRHVSEKCEAVKDGIPNVEKTCDEGSS-PSKPKKGTLEQDPLAEGGHDPSSCPAPLKVEDNTASSPPSAQHLEEHGPGGGEDVLQTDDNMEICTPDRTSPAKGEVVSPLANHRLDSPEVNIIPEQDECMAHPRAGGE-QESSMSESKTLGESGVKQDSSTSVTSPVETSGKKE--GAEKSQMNLTDK-WKPLQGVGNLSVSTATTSSALDVKALSTVPEVKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDDQ-TPSRDGDSQSRSPHRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRDWYSRGRTRSRSSSYGSFHSHRTSSRSRSRSSSYDLHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSGRSYGSDSESDRSYSHHRSPSESSRYS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B5K5-1", "uniprot_id": "A0ACD6B5K5_DANRE", "id": "A0ACD6B5K5-1", "name": "peptidylprolyl isomerase", "aln": "MGVKDRPQCYFDVEINREPVGRIVFQLFSDICPKTSKNFLCLCTGEKGSGKATGKKLCYKGSTFHRVVKNFMIQGGDFTEGNGRGGESIFGGFFEDENFTLKHDRAFLLSMANRGKDTNGSQFFITTKTAPHLDGVHVVFGLVISGFEVIKNIEGLKTDSASRPYADVRVIDCGQLITKSANDVLQGKLRKAFYSE-----DDSQSSSESLSEHSSLEEEPTSRKRKKSSKSKHAKRSRREAKKDRETVKTAGPASHAEGEMAEEND-GEAEQNVKREKPVVRPEEIPPVPENRFLLRRDMPTQEEAIKIDVQDTDIVPNDTKPAVTKSGRKIKGRGTMRYHTPPRSKSRSESECERGSSETPPHWKEEMQRTKAYQPPSVERWSKEE--------RWDDRSDTPRSRSESRE---HSLGEASVYSSQHRSKKEKKKAKQKKKSKKRKHAKKHKKTKTKETSLTDGEVSVSSGKRTKHSSRAERRRSRSYSRSSSRHSHRSY-KSESERRHYLSSSSRDSRSYSRSRSRSYSRSDSRSERRARSSKRSSRSRSGRSVTHSRSRSRSRYRTRSRTRSNSRYSSETPTRSKKRNELRSPRKSKPTEGGISRLDKSVPKSIKGEEAKVQPSASSESVSALPMSDSPPPSRWKPGLKPWKPSYVRIPDTDVKS----------ALASNALTSSSSNAPLETMSSLKQDIAVSQR-DLSSGNSNIPDRLLERSLSRSRSCSQSGS--------CSKSP---THYGNRSSSCSRSESYSSYKERSTVKKRKHFSSHRNAQKRDNHANRHDGGHKDTSPSSEDVSDNPYSPLHVQSDILVQKNTLDSLSALRALALKSKNLNRRKVPLMDKKSASGWESDEENASKTNTAKVHNQHLVKDE-------ELNEMKKRQILSRCWESESDTEIP-DKTAVGEAKYLSEKEEGEASTESEYEY-----------------PLWPNLGAEMSKELKANDEHSADTKPSKHKNKKAKRKHKH-----KRKNSSRSASRKSKAKKTKKHQKP--KETFHWQPPLEFGDEGEEDDSVTQTKQLHKAS--TDAINDGTKRNLKAEQIKQKVSENTDQDQKIVESQQDKLSIESSKVIDENEKMPKIQKSKLHNNTKRDLAQSHP----ETLSNLSDTNLASNKPSDLNKVEPHSPECIP------------EAQQLGPKATGFSPLKNILNNDNVLVPSQKDKVSSITTGSALPQDSKQEETVPGDSCVSVVENKWKPLTGMTAVQTITRKP-FIMKINKQQDQLVGKSQGVKIEIKSKSRVRPGSLFDEVRKTARLNQRPRNQDSSSEEDSLPAAGEKPEAHNHSRSKSKSVSSHRSHRRSRSHSYSHPRSRSRSYTYSSRSYSRSRSRSRYSKGHSRSRSSTYRSYRS-RTHSRSRSRGR-YRGRYRSRSDSYDSYSSHSRSRSRRR---GHRRSKSSDRRSRSYRSYS------RSSSRRRSHSRSSRYS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.:*****:**:**********:***********.*******:**** **:**************************:****:*****:**:*:**** ****************.***********.*********************::**.****:************** * ** :**:: * :*. ** . *.***** ** . .* *::*: .* :::*: *:* ....*. .. ... .* :: *: ..:...***************************. : .: *. : .* **:*:***********:********:* ***. : .************** :**:*** *:*** : ***:** : **** * : .*. * .:*:.::::** *:***.**:**.::*::**.:. :. . . * .: :** ..* **: * ** : *:*.: **:.: : ***** **:*:*:* **.. *:*: .:** ::* .**:** ::* * :* :* : : . ..* *::* . :. :. :. *** . :*.:..:*:************ ******* ** : ..*: :*:. * ***. . * .: : *: * ** .* . .** * *** ::* * *:** :* *: *. *: . ***.. *: . *: *. *:. ::::. . .:.: *: * .. *. : . .. .* * : . ::.* :: . :. * .*.: :.:: . .: : . * :: . *:***::* *. .:.: *:******:::** * * . ** * . ::. ..* .: .. : : :*:** : : :: . .* *.** ***: * *::**********:: **: . .*..* * . .. : * .: : . . . . . : * :: . . : :: :.: : * :.*.. .: ::.: . :. * * ** : : :. :.:.:.* .. ** : *. .*:* . .* :.: :: **** *: : . . . :.:: *.**::******.:*****************:*****:***::: *: . ..:::. **:*** :. * : ** *:*:*:.**** : :* **********. **:*::*****:* *::* ** ******. * : **** :**** *:****** : .::*.:* :***** ***. ** *::** *.*****", "identical_positions": 579, "similar_positions": 395, "identity": "38.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1735", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88480-1", "uniprot_id": "CABIN_RAT", "id": "O88480-1", "name": "Calcineurin-binding protein cabin-1", "aln": "MIRIAALNASSTIEDDHEGSFKSHK-IQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEARLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRLPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSVHEVSVNAAETQAIVDEALGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDLSDYQDPSQLLAPSIVVTPVSVVQPSPVCTNPTVAVAEP-----VLSYTSVTTTSFPLHSPGLLDTGTPMG--------------------------DVSG-----GDKSKKGVKRKKTLEESGETAKRRSARVRNTKCKKEEKVDFQGLLVKFLPSRLRKLDPEEEDDPFNNYEVQSEAKLESFSNVGPHRLSFDSATFMESEKQDVHAFLMENLTNGGVLELMMRYLKSMGHKFLLKWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKDMMLMSLSCMELQLDQWLLTKGRSSTVSPRNCPAGVVTGRFGPDFPGTHCLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEILQSSTALQAQAGAEQRDIVIRLPNLHNDSIVSLEEIDKNLKSLERCQSLEEIQRLFEAGDYKAVVQLLRPTLCT-SGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLEEHRQCFECSDVALNEAVQQMLNSSDS--AAKEEWAATVTQLLLGMEQALSSDSRGSILKESSSPTGLVRLTNNLIQVIDCSMAVQEEPKEPYVSSVLPWIILHRIIWQEEDTFRSLCHQQQLQNPTEEGISEMPMLPSSLMLLNTAHEYLGRRSWCCNSDGALLRFYVHVLQKELAASASEDTHPYKEELETALEQCFYCLYSFPSKKSKARYLEEHSAQQVDLTWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTEKPALSMDKVSAYIEGTSAEVPCLPDGADPAPPVLNELYYLLADYHFKNKEQSKAIKFYMHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWRHATPVLNCFRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRAELPPEVVQQMEDRRDSMLETARHCFTSAAHCEGDGDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLLGKPDSG--------VSAEVLVSFMKEAAEGPFARGEEKNTPKAS-EKEKACLVD-EDSHSSAGTLPGP------------GASLPSSSGPGLTSPPYTATPIDHDYVKCKKPRQQATPDDRSQ----------------------------------DSTAVALSDSSSTQDFFNEPTSLLDGSRKLLPEKRISGLSAQAGPSGKDLPGPTEERG-------------------KTEESLESTEAFRVVEPSVQKP--------VADSSASAYIPSKPAVSTPPPWDGKKRSDPLG--EPVAFPQGLPAGAEEQRQFLTEQCIASFCLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGLEHPGSKACGLSGARMTTDVSHKASPEDGQESLP--HPKKLPLADGSGPGPEPGGKVGPLH---QLPVATDTRDNTEQGGEPKDKERPPVGPTEPMDTGETAARHPDLEPTPRLLPGRPPRDRGPES-RSAELSLEELSISTRQQP---APLVPSPVTP-TTAAPTTMGARAAGHPEEAPPRPNRKRKLLQDTESGKTLLLDAYRVWQQGQKAMAYDLSRIEKIMSETYMLIKQVDEETALEQAVKFCQVHLGAAAQRQASGDAPTTPKHPKDSRENFFPATVAPSAPDTTAPDALQRPSDSHLKP-----GLAAAITCPPSASASTP----DPGIPQPHRPEAVPSRAPLSPDGEEVSGVTEGPSFLSQEPRHSHQMKMAATGPLAEQHCWPVEAACQTGAEPTFSQ-----------------------------ATSTKVPSSGSTQTPESHQGKTESSRAKSRLLPNMPKLVIPSATTKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDFMDV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3X8Q1-1", "uniprot_id": "G3X8Q1_MOUSE", "id": "G3X8Q1-1", "name": "Calcineurin-binding protein cabin-1", "aln": "MIRIAALNASSTIEDDHEGSFKSHK-IQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEARLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRLPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEALGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYSHLTTCEPPRPSLGKRIDLSDYQDPSQLLASSVVVTPVSVVQPSPICTNPTVAVAEP-----VLSYTSVTAASFPLHSPSLLDTGTPMG--------------------------DVSG-----GDKSKKGVKRKKTVEESGETAKRRSARVRNTKCKKEEKVDFQGLLVKFLPSRLRKLDPEEEDDPFNNYEVQAEAKLESFSNVGPHRLSFDSATFMESEKQDVHAFLMENLTNGGLLELMMRYLKSMGHKFLLKWPPGLADVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKDMMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGVVTGRFGPDFPGTHCLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEILQSSSAIQAQAGAEQGDIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLFEAGDYKAVVHLLRPTLCT-SGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDHRQCFECSDVALNEAVQQMLNSSES--AAKEEWVATVTQLLLGIEQALSSDSSGSILKESSSTTGLVRLTNNLIQVIDCSMAVQEEPKEPYVSSVLPWIILHRIIWQEEDTFRSLCHQQQLQNPTEEGIPEMPMLPSSLMLLNTAHEYLGRRSWCCNSDGALLRFYVQVLQKELAASASEDTHPYKEELETALEQCFYCLYSFPSKKSKARYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTEKPALSMDKVSAYIEGTSAEAPCLPEGADPTPPVLNELYYLLADYHFKNKEQSKAIKFYMHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRSELPPELVQQMEDRRDSMLETARHCFTSAARCEGDGDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLLGKPDSG--------VGAEVLVSFMKEAAEGPFARGEEKNTPKAS-EKEKACLVD-EDSHSSAGTLPGP------------GASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQAAPDDRSQ----------------------------------DSTAVALSDSSSTQDFFNEPTSLLEGSRKLFPEKRLSGLSAQAGPSGKDLPGPTEERG-------------------KTEESLESTEAFRVVEQSVQKP--------VADSSASAYIPSKPPASTPPLWDGKKRGDSLG--EPVAFPQGLPAGAEEQRQFLTEQCISSFCLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGSEHPGSKACGLSGARMTTDVSHKASPEDGQESPQ--HPKKLPLADGSGPGPEPGGRMGPLN---QLPVVTDIRDNTDQGGEQKDKESPQVGPTEPMDTSEAAGRHSDLEQTSRLLPGRPPRDRGPES-RSAELSLEELSISTRQQP---APLAPSPAAPTTTAAPTTMAARGAGHSEEAPPRPNRKRKLLEDTESGKTLLLDAYRVWQQGQKGMAYDLSRIEKIMSETYMLIKQVDEETALEQAVKFCQVHLGAATQRQASGDTPTTPKHPKDSRENFFPATVVPTVPDPTAPDALQRPSDSHLKP-----VLATVITCPPSASASIPDLSTDPGIPRPHRPETTPSRAPLSPEGEEASGVTEGTSILPQEPRYSHQIKMAATGHLAEQHCWPVEVACQTGAEPTCSQ-----------------------------ASSTKVPSSGSTQTAESHQGKTESSRAKSRLLPNMPKLVIPSATTKSPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDFMDV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6J0-1", "uniprot_id": "CABIN_HUMAN", "id": "Q9Y6J0-1", "name": "Calcineurin-binding protein cabin-1", "aln": "MIRIAALNASSTIEDDHEGSFKSHK-TQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEALGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDLSDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEP-----VVSYTSVATTSFPLHSPGLLETGAPVG--------------------------DISG-----GDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPSRLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLTNGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKDMMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERRDIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCT-SGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEA--AAKEEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEPHVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLGRRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKARYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTERPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGDGDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLLGKPDSG--------VGAEVLVNFMKEAAEGPFARGEEKNTPKAS-EKEKACLVD-EDSHSSAGTLPGP------------GASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDDRSQ----------------------------------DSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERG-------------------KNEESLESTEGFRAAEQGVQKP--------AAETPASACIPGKPSASTPTLWDGKKRGDLPG--EPVAFPQGLPAGAEEQRQFLTEQCIASFRLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLP--QPKKPPLADGSGPGPEPGGKVGLLN---HRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPES-RPTELSLEELSISARQQP---TPLTPAQPAP-APAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDYMDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B598-1", "uniprot_id": "A0A8M3B598_DANRE", "id": "A0A8M3B598-1", "name": "", "aln": "MIRIAALNAASQAADEHEDAFRSTKPGQTKEAQEAEAFALYHKALDLQKHDKFDESAKAYHELLKTPLLKEAVASEDEKVGLKHPGLMLKYSTYKNLASLAVLKDDLDTAMDFYVQAVMLDSTDVNMWYKMGKLALRKVSMPLARHAFEVGLHCNPEHWPCLDSLITVLYALSDYSCCLYYICKALEKDSGYSKGRVLKEKIFQEQPCLRRDSMKMFSKLDISLQYVDVDEEEAHSIVEEALELRRQRQAKLTRHPVADLQLVQPIKYFTWKSVGESFLAMYKHQNACLVPRPDFGRRIDLSMYRDPDCLLQMPISAPVPAAAAAPSDPPQPTVPISDPPAPVVLPPAPSSPSASLPPCPELLLQAITVAGGVPLNQNVIEITTTTTVTTTAASAVEDTAGNSAALDDKVKKGTKRKRVIEDTVETAKRRSARVRNTKCKKEEKIDFQELLLKFLPSRLKKFEDDEDEESLSNMDSQCGIKPDSQLNHGSN--SSNYIVSMESERSEVHAFLMANMQNGGILELMIYYLKAVGQKFLEEWPAGLSGVVLDLFNCWRKHSAGLPNPLLRDSSNKHIKEMMLMSLGCLELQLEQKSMMKGKNASQRKTMSASGRDCG--DLDSPETRFQADLFLLTMASSQRDLFEDHWLSFAIRVHWLKARHLAFQGDMEEALECYDMCVGLLKG-------QTSENDKIAIHLPNLSVDNSISIEEIEKKLKSLERCQSLEEIQKLFDAGDYQSVVRLLQPTLSFGHGAARLKPLDYISSAPERPAQLLLLQSSLLRQKDFSSCLETTEVSLNEALQHLNSALPSSPSAKEEWISTITALLKGIESCITDKP--ELLRQTPRSANLPRLANNLIQLIATSMVLPDDPKEAHFSSLLPWILLYHLIKQEEAAFDCMLRQHIADEEDEE--DDTPLLPSSLMLLNTAHECLGRRSWCCNSDGALLKFFMRVLREKLSG---HENLPYKEDLEMALEQCFFCLYAYPSKKSKARYLEEHSAPQVELHWKEAVFMFEYFKPKTMPEFDSYKTSTVSADLANLLKRLSGIIPRTDGPTLSIDDVSAYIEGGAVKVPALPEGASPAPPVVNELYYLLADYHFKNKEQSKAIKFYMHDICMSPNRFDSWAGMALARASRIQDKLNSNELRSDGPIWKNSLAVLTCFRRALEIDGSNLSLWIEYGTMSYALHSFASRQLKQWGHQLPADLTKQMEERRDSMLETASQCFQSASRCDGD--EEEWLIHYMLAKIAEKRKQPPKDYLQMYKKSAHYLHEEAARYPRKIHYHNPPDLAMEALELFFRLSATILKLLENVENTGEQAETKLLDYDLFFCLLTEAAVGPFARGEEKTAPKTSSDKEKLLSVNDEDSLSSAGVMTCPAAMTGSASVAAAGASLAGDGAAGASSPPYAVTPLDHDYAKRKNLQQRHRQGEQIQRQQQRQQQDADFSLDHDYCVCVSALRPGSVYEQSQDSVAGLSDSSSLQDVFMDATSSQDSSHKLHPVK-CSIFPEDSNATGKEKQATVEDTGPLEDKNMDFSSATLSQESSVTQESSDTTLSITSPEASVPKTPTADPLSQAPSVPQPPTTPNRPHPQTGPSSESKRRPEPPPPLEAMELPKALPAGREEQRKTLVDVCVRCLFLCLSRYPQHYKSLYRLAHLYAYSNTHKNLQWARDVLLGSSVPWQQLKHMPAQGLFCERNKTNLFNGIWRIPVDEIDRPGSFASHMNRSIVLLLHVLSQLKDHHTLLKISLMLQRTPDQGKKYLRDVDRQALAKRAFFFTVKVLEDNLDKLTGTSDPPKPSATGMG-EMTTTDVSNRPPAAEDPKSSQSSQPKTAVPETPTATGGESGLPSFPQKCSATLQLSLEPLPQATASTLQATSEPMELGSGSWLSSSKFKDPHVDAGSQEIVKSAAEETEKLPESSRASELSLEELSISTKQQQQQQQQIQNQVNAAKPATTPITPTPLPSGADLVVPQRPSRKRKLLDDVESGKTLLLDAYRVWQQGQKGMTYDLQRIEKIMSETYMLIKQVDEDVALDQAVKFCQIQMATSAQRQSSSEAPSTPKFTKEQRDIFFPASFSTPCLHTHTHPASVQDAEARLSKT----PRPLLIQTQTHSTPAQIYCQTDQSQQRKTTSQPIASMAFLPHTEDREEPVSEGLLYRQQESHLCQQMKMATVSQIHNTHEWAAHEP------PSCST-------------------------------------HSSTESEQSKQN--DPSRIRSRIPPNMPKLLIPSTVTKFPPEITVTPPTPTLLSPKGSISEETKQKLKNVILSSQSAANVKKDTLAQPALEVQETSSQESSLESESDEEDDYMDI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********:* *:**.:*:* * ************************:*:**********:: **:***:* *** *******:**********.**. ::**:***:**::**********:***:*::*** : :******** **:***:******.******:****: ***:********. **** *******:******:**::** * *:*:: *.*. *:::**:*** **::*** :.*. .**:***** :****.:***:****.* .:* ***.:*:***** *:**. * .: .. . ... .:*:*.:::* : . .* .::*:* . **:: : * * :* .** ***.***: *:: ********************:*** **:*******:*:: :*:::.:.* : *. * :* . *.: * : . ****:.:** **: *: ***:****: ***::*:*** .**.**: ***.:::.**:**:.********.******:******.*:****:* : **:.:: ..:* * . * * *: .**: *::********** **.*.:**:*****.**:*****:*** **:*. :*:. :*. .*.*:**** *. :*:***:*:**************:*::****::**:**:***. * * * *::::* ***********.**** ::. .*:* ::*:****:*:: .: : :***** :*:* ** *:*..:: .. .:*: :. .:.* **:*****:* **.: ::.**.:.**:****:*:::* *** :* .: :*: :: ** : *:************* ***************:*:::**:::*:. .:. ****:** ******:***::*************** **:* *::*:**********:*********************:: *:***: *:**:*.******* :.:.*.**:**.*:***:*****************************:.***************************:******::: .**.*********.*************************** :**.::.:*** ********* :** **::*:** **********.*:***::***. ** *:::.***********:********:*******::*** *:***** : :. :. :::. ::.*** *********.:**:* :*** *: *** ****.:. * ****......* :****:.**:****.* *: :*: .:: * :.:...****** **.* :.** :.*:* . * . :. ::..:**: ...*: * .:** ::* .: * .* *. ... . .. *.:* .* . :.*:* : *.: :*:.**** ****: *.: *: .: *****:***********.**:**:**:*************:*****:***************:******************* **********:**:**:** ****:* ***************.***.**:***::*******.*.:*: : * ... *: *****::... :. :. :**. :..* *.* : : : .: . .* *. . :.:.: * * : .. :: *** *.:**********::** : :. ..:.. * . .* * .******:*.*******************.::*** *:*:**************:.**:*******:::.:::***:*.::*:***..*:.*: ***.:. .. .. . : : :::: . . * . ::.: * . : .:. .* * * :. *:** **.: . *:***... : * *... . *: * .*::. :.: . :.** :** ******:***:.** *****************************..***:******:*::*.****** ************:**:**:**:", "identical_positions": 1198, "similar_positions": 584, "identity": "50.87%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1747", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R885-1", "uniprot_id": "M0R885_RAT", "id": "M0R885-1", "name": "", "aln": "---------------------------------------------MHRGGQPLKKRRGSFKMAELDQLPDE-------------------SSSAKALVSLKEGSLSNTWNEKYSSLQKTPVWKGRN---AGPAVEMPFRNSKRSRLFSDE------------------DDRQINTKSPKRNQRVAMIPQKFTAT-----------------------------------------------------------------------------------MSTPDKKASQKIGFRLRNLLKLPKAHKWCIYEWFYSNIDKPLFEGDNDFCVCLKESFPNLKTRKLTRVEWGKIRRLMGKPRRCSSAFFEEERSALKQKRQKIRLLQQRK----VADVSQFKDLPDEIPLPLVIGTKVTARLRG-IHDGLFTGQIDAVDTLNATYRVTFDRT-GLGTHTIPDYEVLSNEPHETMPIAAFGQKQRPSRF--FMTPPRLHYT------------------------------------------------PPLQSPITDGDPLLGQSPWRSKISGSDTETLGGFPVEFLIQVTKLSKILMIKKEHIKKLREMN-----------TEAEKLKSYSMPIGIEFQRRYATIVLELEQLNKDLNKVLHKVQQYCYELAPDQGLQPADQ---PTDMRRRCEEEAQEIVRQANS-ASGQPCVENENLTDLISRLTAILLQIKCLAEG--GDLNSFEFKSLTDSLNDIKNTIDAS-NISCFQNN-VEIHVAHIQSGLSQMGNLHAFAANNTNRD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C735-1", "uniprot_id": "LIN9_MOUSE", "id": "Q8C735-1", "name": "Protein lin-9 homolog", "aln": "-------------------------------------------------------------MAELDQLPDE-------------------SSSAKALVSLKEGSLSNTWNEKYSSLQKTPVWKGRN---AGPAVEMPFRNSKRSRLFSDE------------------DDRQINTKSPKRNQRVAMIPQKFTAT-----------------------------------------------------------------------------------MSTPDKKASQKIGFRLRNLLKLPKAHKWCIYEWFYSNIDKPLFEGDNDFCVCLKESFPNLKTRKLTRVEWGKIRRLMGKPRRCSSAFFEEERSALKQKRQKIRLLQQRK----VADVSQFKDLPDEIPLPLVIGTKVTARLRG-IHDGLFTGQIDAVDTLNATYRVTFDRT-GLGTHTIPDYEVLSNEPHETMPISAFGQKQRPSRF--FMTPPRLHYT------------------------------------------------PPLQSPITDGDPLLGQSPWRSKVSGSDTETLGGFPVEFLIQVTKLSKILMIKKEHIKKLREMN-----------TEAEKLKSYSMPIGIEFQRRYATIVLELEQLNKDLNKVLHKVQQYCYELAPDQGLQPADQ---PTDMRRRCEEEAQEIVRQANS-ASGQPCVENENLTDLISRLTAILLQIKCLAEG--GDLNSFEFKSLTDSLNDIKNTIDAS-NISCFQNN-VEIHVAHIQSGLSQMGNLHAFAANNTNRD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TKA1-1", "uniprot_id": "LIN9_HUMAN", "id": "Q5TKA1-1", "name": "Protein lin-9 homolog", "aln": "-------------------------------------------------------------MAELDQLPDE-------------------SSSAKALVSLKEGSLSNTWNEKYSSLQKTPVWKGRN---TSSAVEMPFRNSKRSRLFSDE------------------DDRQINTRSPKRNQRVAMVPQKFTAT-----------------------------------------------------------------------------------MSTPDKKASQKIGFRLRNLLKLPKAHKWCIYEWFYSNIDKPLFEGDNDFCVCLKESFPNLKTRKLTRVEWGKIRRLMGKPRRCSSAFFEEERSALKQKRQKIRLLQQRK----VADVSQFKDLPDEIPLPLVIGTKVTARLRG-VHDGLFTGQIDAVDTLNATYRVTFDRT-GLGTHTIPDYEVLSNEPHETMPIAAFGQKQRPSRF--FMTPPRLHYT------------------------------------------------PPLQSPIIDNDPLLGQSPWRSKISGSDTETLGGFPVEFLIQVTRLSKILMIKKEHIKKLREMN-----------TEAEKLKSYSMPISIEFQRRYATIVLELEQLNKDLNKVLHKVQQYCYELAPDQGLQPADQ---PTDMRRRCEEEAQEIVRHANS-STGQPCVENENLTDLISRLTAILLQIKCLAEG--GDLNSFEFKSLTDSLNDIKSTIDAS-NISCFQNN-VEIHVAHIQSGLSQMGNLHAFAANNTNRD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RHQ8-1", "uniprot_id": "LIN9_DANRE", "id": "Q5RHQ8-1", "name": "Protein lin-9 homolog", "aln": "-------------------------------------------------------------MAELEQLLDE-------------------SSSAKALVSLREGSLSNTLNEK-NNLPKSQTTRGRS---SYVSMETPTRSSKRSRLSCED------------------EERPIASRSPRRSQRVTTMPQKLTN------------------------------------------------------------------------------------VATPDKRVSQKIGLRLRNLLKLPKAHKWCIYEWFYSNIDRPLFEGDNDFCLCLKESFPNLKTRKLTRVEWGTIRRLMGKPRRCSSAFFAEERMALKQKRQKMRLLQQRK----ITDMSLCKDLPDEIPLPLVIGTKVTARLRG-VHDGLFTGQIDAVDTSAATYRVTFDRN-GLGTHTVPDYEVLSNEPHETMPISAFAQKQRPPRFQNFLTPPRGSYT------------------------------------------------GSTQSILMDNDPLFSQSPWRSKLTGTDGETLGGFPVKFLVQVTRLSKILMIKKEHIKHLKEMN-----------TEAEKLKSYSMPIGLDLQKRYATTVLDLEQLNKDLNKVLHEVQQFCFELAPDQGMQPADQ---PSELRRRCEEESQDVLRQNNTLASGEPRVQNTELTQLISRLTALLLQIRCLAEG--GDLNSFEFKSLTDSLNDIKSSIDDS-NLSCFQDN-VEIHVAHIQSGLSQLGNLHAFSANNTNRT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W542-1", "uniprot_id": "Q9W542_DROME", "id": "Q9W542-1", "name": "", "aln": "MLTGRPVRMSVAVNQKGWGKKAGASVSDSAIRTQSALSEGGGAIDVRPMEHDEEINREDLNLDEDDEMEEEEEEEHADEEDDDEEPDSNENSAPEEQVEPPAFSLATLGLQRVGSAPPPKPKVQKAPIPTLNARGMPARIRKRNRLFYDENIINDDKPLRMSLAPKKTPGRPPQSAGGGSSQKIPLTPSKVLKKRKGVVSRYMRSSEQGTNSVSASNQPQLLGKHKKATPSKSQSVGSKLGSGGPKTGRGAHFIGKGTAAAVAAVAAAEEEANQAEAAALANKRLGQSIGLRLRNLLKLPKAHKWAIAEWFYSYVDKPLFECRDEFMNHVNELAPRLGTRSLIRHEWVNIRRRMGRPRRCSAKFFSEERKELDRKRQVIRTLQSRKPGEFKDSVSMLSDMPEKIPMTLPLGTKVTARLRS-PQDGIFAGTVAAYDSLNAMYRVTFERI-GLGTHAIPDYEIVSENFHEMLPLHSFTKDFRPNLMSIYQTNNLGFTTNLGFTANLTNNYLQKKEKIDGGAGAAAGAGSLYFKPQKHLATNNAAARNALSMKLNKSDPLLGQDSVGVSPIRQQLTRNRGYSTSLLEHLVRLEKYIAVKADRIQRLNKMNGTAELAMGDMISHDENGDRHRRQIAVNFQRQYAFNIVTIERINAELMFELTKVQELSSSLTRNPNVQAMIS---PTYLREECRAKASQTVDDINK-----GMVKNTRMIKLLKDLTTLLIVTQNLGGD--CEVSEVN-EVLEGCLEEVRSNLICSENREVFQMS-VQGRLEYIAMDISRRLEEKSLSRVADGDDDIKSLKSEDETDEDHVQDHKHGADEEPAADTSKTKAKGSPKQVEGKENSEVDKMDHSSHPMDTDTEKEEKLESGGSENAGYASQQRQDEDQDTEEQHLDLEEQHLDPEEHHLDLEEQHLDPEEQHLDLEEHHLELEEQHLDPEEQSLNPAVTEDTQITIESMKESDEEFQSAAETEEDDMVGLIMEEEEEEEFVYDKDL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZW3-1", "uniprot_id": "Q9VZW3_DROME", "id": "Q9VZW3-1", "name": "", "aln": "--------------------------------------MSVDPLSIDNFTIQSEICEENEFLANIGLLSTT-------------------TMSRHQLKKPRKMVAAWQNDELFIKRPNFAPRIRISEKPEIQGRIKPGVASKRTENFTKK-----------------PSNISVDVSEDEKAKEKEKEQDPYSN--------------------------------------------------------------------------------------------DFILGKRLYNFLKYLSSHRWIWCEFVDSFLDKPTLTMGYDMKRFIAEYCPLLHSCFMPRRGWQLVRRNMGKARRFSAAFIELEREELECQRRIVRQLQQHKFNP-KENVGYLDQIPKRVPLPLAKDATVSSFLHGNSFEGIVNGTVMGYDPQDYTYLVRFNRNDNAVVLSLPDSQLYSDEETAAVPLSIIMRGNKSSSVISESAKTEKFGN------------------------------------------------KRYTKELLESVLRVG--------------KLQDVKHKILMDLARMN-------EDFETFKEIG-----------SSSSRRDAKVTPQRENLQRRYSASMITLHRVNADILEPLRILHDYLVEYQKQDEEEESKRGRPASEVYQKCRMQAEQDLKTAAD--EKFLKIESDRTQEFVRNLHTILYLNGKLGRENSSNLETIIADLVTHMVDNIQPSLGRKLKDGVDSLEPLRQQVVQIFKDVKKPERFQITQQAPMQTEDGIYNFVVEAQPDTPS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . : . . : : . . * **.. .. :. . . :* ** *:** .:*:* *:. * :*:* : :: : * * * : : * * :** **:.** *: *: ** *. :*: :* **.:* .:. .::*..:*:.* .:.*:: *:. :*:. * : . *. * * *:* . . ::** :: *:: :*: : : :. . : . : .. .. . .:* .:.::. : :: :.::. : .. . ::*::*: :: :.::* :: * ::: . : : .: : ..*. ::.: : ::. . .:: * ::* *. ::. . . : ::::: .: . : . . :. :: * .:.: . : ", "identical_positions": 62, "similar_positions": 180, "identity": "6.2%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1768", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q13740-1", "uniprot_id": "CD166_HUMAN", "id": "Q13740-1", "name": "CD166 antigen", "aln": "MESKGASSCRLLFCLLISATVFRPGLGWYTVNSAYGDTIIIPCR--LDVPQNLMFGKWKYEKPDGSPVFIAFRSSTKKSVQYDDVPEYKDRLNLSENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETEQLKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRLRSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVTLTCTAENQLERTVNSLNVSAISIPEHDEADEISDENREKVNDQAKLIVGIVVGLLLAALVAGVVYWLYMKKSKTASKHVN-KDLGNMEENKKLEEN-NHKTEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61490-1", "uniprot_id": "CD166_MOUSE", "id": "Q61490-1", "name": "CD166 antigen", "aln": "MASKVSPSCRLVFCLLISAAVLRPGLGWYTVNSAYGDTIVMPCR--LDVPQNLMFGKWKYEKPDGSPVFIAFRSSTKKSVQYDDVPEYKDRLSLSENYTLSIANAKISDEKRFVCMLVTEDNVFEAPTLVKVFKQPSKPEIVNKAPFLETDQLKKLGDCISRDSYPDGNITWYRNGKVLQPVEGEVAILFKKEIDPGTQLYTVTSSLEYKTTRSDIQMPFTCSVTYYGPSGQKTIYSEQEIFDIYYPTEQVTIQVLPPKNAIKEGDNITLQCLGNGNPPPEEFMFYLPGQPEGIRSSNTYTLTDVRRNATGDYKCSLIDKRNMAASTTITVHYLDLSLNPSGEVTKQIGDTLPVSCTISASRNATVVWMKDNIRLRSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIHWTITGSGSVINQTEESPYINGRYYSKIIISPEENVTLTCTAENQLERTVNSLNVSAISIPEHDEADDISDENREKVNDQAKLIVGIVVGLLLAALVAGVVYWLYMKKSKTASKHVN-KDLGNMEENKKLEEN-NHKTEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QE54-1", "uniprot_id": "F1QE54_DANRE", "id": "F1QE54-1", "name": "", "aln": "MQRTAFLTC------LLTVSLMNQVCGLETVTGKYGDTVEIPCNSGLVSDVGVTFVKWKSDK-DGS---ILVKHTGQNASSPTDG-NYKNRVSIKKDFGLIITQVSLADQKTFTCMVVAADDILEYPVQLVIYKTPLQPQIANLTTAMEIGKLTTLAQCHTEGANPAANITWFKNKTPLIADGTAIKITNDVAVDKATGLSATTSKLEYTAVKDDINSKFTCQVQHIKSAN---MDSSPLVFTVNYPSETISFHVLP-DGPVKEGDNVTLKCTADGNPPPSRYNFYIKGEKKTVEKSNIFILSNVTRQNTGEYKCSLVDNEILTASKNITVEYLDVILSTTGEVFKKLGDSFETTLDIKASGKTETFCKKGGEKMVGPPKFASLKYTDSGVYECVVT---MLGLKKTQTFDLNVHGQPLIKSLTKKRGDGTNKILSCEAEGSPKPTVQWITNGTDVKFQESE---HVNGKITYYITVSPKANVTVSCTISNDLGSDTRSIDVSSLVEDVTMDKQDQS----EDYSDQTALAVGIVVGLMLAALLIGLAYWLYMKKFRQGSWKTGEKEDGSAEESKKLEENQSQKAEV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . :* *::.:::. * **.. ****: :**. * .: * *** :* *** * .: : ::: . * :**:*:.:.::: * *::. ::*:* *.**:*: *:::* *. : ::* * :*:*.. : :* :*..*.:* :..: * .****::* . * . : * . :* * * : **.***.:.: **: ***.* : .:. : *. :* : **:* ::::*** ...:*****:**:* .:*****..: **: *: : :..** : *::* *: **:*****:*:. : **. ***.***: *..:*** :::**:: .: *.** :: .. *.. :: ..*.*:**:* *:* * * .: : **** ::: * *.*:* ** .*. .* .* : *..** ***:::* .*:. ::::* ::**: * :**: ***::** .*:* ..*::**:: : :: * *. .**: * *******:****: *:.******* : .* :.. *: *. **.****** .:*:*.", "identical_positions": 205, "similar_positions": 209, "identity": "34.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1770", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CRG1-1", "uniprot_id": "TM7S3_MOUSE", "id": "Q9CRG1-1", "name": "Transmembrane 7 superfamily member 3", "aln": "-MWRLRLLVLAVLA-----AGSAEAQANSSDGFLEFSVGKFTYFVLSKSSPQEAVLRHISSNVTFLLFQIHSQYQNTTVSFTKTLLPSTSGTGNDRGLVFILRPEQAVCTWYLETGDTKPVQSVALTLSYSERDPIPGGCNLEFDLDIDPNLYLDYNFFETTIKFAPANIGYARATEPPPCDVSTSRESRWRLRYDVYQYFLPEGDLTEASLLHHLQRMAQVAQVKASAIKVATLTADDKTAVSFSSLPGQGVIYNVIVWDPSLNTSAAYVPVHTYACSFESVDGNCASPGRVSTKVFSTLFALLGLFVCFFGHRFWKTDLFFVGFIFLGFFFYILITRLTPLQYDVRLALTAVAGSFGGLLLVASWWRFGILTLCMLCVGLVLGFLVSSGTFFTPLGNLNVFHDDGVFWVTFSCIALLVPVIFMGCLRILNILACGVVGSYSVVLAVNSYMFTSLSYITLNVLRRALNTDFRGAFIRVPFQTNDYIILAVWGMLAVSGITLQIRRERGQPPFPPHPYKLWKQERERRVTNILDPSHHIPPLRERLYGRVARIKELFQKEQPAGERTPLLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NS93-1", "uniprot_id": "TM7S3_HUMAN", "id": "Q9NS93-1", "name": "Transmembrane 7 superfamily member 3", "aln": "-MGFLQLLVVAVLASEHRVAGAAEVFGNSSEGLIEFSVGKFRYFELNRPFPEEAILHDISSNVTFLIFQIHSQYQNTTVSFSPTLLSNSSETGTASGLVFILRPEQSTCTWYLGTSGIQPVQNMAILLSYSERDPVPGGCNLEFDLDIDPNIYLEYNFFETTIKFAPANLGYARGVDPPPCDAGTDQDSRWRLQYDVYQYFLPENDLTEEMLLKHLQRMVSVPQVKASALKVVTLTANDKTSVSFSSLPGQGVIYNVIVWDPFLNTSAAYIPAHTYACSFEAGEGSCASLGRVSSKVFFTLFALLGFFICFFGHRFWKTELFFIGFIIMGFFFYILITRLTPIKYDVNLILTAVTGSVGGMFLVAVWWRFGILSICMLCVGLVLGFLISSVTFFTPLGNLKIFHDDGVFWVTFSCIAILIPVVFMGCLRILNILTCGVIGSYSVVLAIDSYWSTSLSYITLNVLKRALNKDFHRAFTNVPFQTNDFIILAVWGMLAVSGITLQIRRERGRPFFPPHPYKLWKQERERRVTNILDPSYHIPPLRERLYGRLTQIKGLFQKEQPAGERTPLLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QC74-1", "uniprot_id": "F1QC74_DANRE", "id": "F1QC74-1", "name": "", "aln": "MPLKRECLVLLVLS----WVGSLRAQ---DENRVVFSLGTFQNVSIPVNGTVQAVVSRIPADVSFITLQFHTQHRNVTLSYLQEPLFGFFVTAEDAGLLSTLIPSQFSISWFLNTPDGSSAAAIGVILPYTSTDPVPGACNQEFPMEIDPNIYLKYNLFETTITFAPANLGYGRGEIPPACDVQTDSSTRWRLVYEVYQFFLPEGDQSEQSLISSMERVANVQNVQDNSRKVVSLSSQEKTQFSFMSLPGQGVIFSVIVRDPVLNTSASYIPVHTYACSFNSTLDGCQDLDKVSTKVFFTVLGLAGLFVCFVGHRFFKCELFGMGFGFMAFLFFVLITRTTTLDYNIRLALTALMGVVGGVVLVMSWWRFGSVLACVLVVGLILGFLISSVVFFTPLGDLPVFHNDVVFWVVFVCIIVVVPLFFIRWPREGNIMTCGVVGAYTVVLAVNAYTYTSLSYITLDVLKRFLNHNFSRAFISVPLQDIDFVMITVWVVLGVSGIIVQLYREKSRPFFPPSPYVLWRQERERRKTNVLDPSYHKPSLPAQIMG---RIRQLTRRAEPAGETTPLLL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **: **: .*: .. .:. : **:*.* . : . :*:: *.::*:*: :*:*:*::*.*:*: * . *. **: * *.* :*:* * . ... :.: *.*:. **:**.** ** ::****:**.**:*****.*****:**.*. **.**. *. .:**** *:***:****.* :* *: ::*:..* :*: .: **.:*::::** .** ********:.*** ** *****:*:*.*******:: ..* . .:**:*** *::.* *:*:**.****:* :** :** ::.*:*::**** *.:.*::.* ***: * .**:.** ***** : *:* ***:****:** .******:* :**:* ****.* ** :::*:.*: * **::***:*:*:****:::* ********:**:* ** :* ** **:* *:::::** :*.**** :*: **:.:* *** ** **:****** **:****:* *.* :: * :*: * :: :**** *****", "identical_positions": 268, "similar_positions": 173, "identity": "46.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1783", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FCE7-1", "uniprot_id": "F7FCE7_RAT", "id": "F7FCE7-1", "name": "", "aln": "-MATPGSEPQAFAPALSVTALHPHIHQH-------HQHHGSTGSAG-----------FNLPLNRGLERALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTHLNLSRNQLSALPACLCGLPLKVLIASNNKLGSLPEEIGQLKQ-LMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPPELVDLPLVKFDFSCNKVLVIPVCFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQ-IKTADS--LYLHSIERPHSHQHVEDS--------KKDSDSGVGSDNGDKRLSATEPSDEDT-----VSLNVPMSNIAEEDQTTKEDACHRLAPAEG----DFQPTPSLLGDSGSSGQEREQFAGRADVLHCELMNYIKDQAEDCEELLRIEEDAHWQTEE--LLNSSKDQDLDIVMIEQLREAEDLLQGPNGLTTDITERSILNLY----------------------PMCSAEALEFPD--------SSLNGQLQLERSPEREVQN-DVTLQSNGSQCSPNEIRED---SPSGSPTANITAPFGLK--------PRSDPALILPPVSFNKLTQAQTWDSSSYSVPSEGD---SDNVFLRPQRNLESIDPQFTIRRKMEQMREEKELVEQLRESIEMRLKVTLHEDLGAALMDGVVLCHLANHVRPRSVASIHVPSPAVPKLSMAKCRRNVENFLEACRKLGVPEADLCSPYDILLLD-FRHIRKTVDTLLALGEK--------------------------PPQSTSALRSRDLIGFCLIHVLLTVLVLIAYRWNALSA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62046-1", "uniprot_id": "LRCH1_MOUSE", "id": "P62046-1", "name": "Leucine-rich repeat and calponin homology domain-containing protein 1", "aln": "-MATPGSEPQAFAPALSVTALHPHLHQHHQHHQ-HHQHHGGTGGTG-----------FNLPLNRGLERALEEAANSGGLNLSARKLKEFPRTTAPGHDLSDTVRADLSKNRLVEVPMELCQFVSLEILNLYHNCIRVIPEAIVNLQMLTHLNLSRNQLSALPACLCGLPLKVLIASNNKLGSLPEEIGQLKQ-LMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPPELVDLPLVKFDFSCNKVLVIPVCFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQ-IKTSDS--LYLPTIERPHLHQHVEDS--------KKDSDSGVGSDNGDKRLSATEPSDEDT-----VSLNAPMSNIVEEDQTIKEDACHRLTPTKG----EFQPKPSILGDSGISGQEREQLAGRADARHSGLMNYIKDQAEDCEELLRIEEDAHWHMEE--LLNSSKDRELDIAMIEQLREAE-LLQDPNGLSADIIERSILNLF----------------------PMDSGEASEFPD--------PSLNGQLQLETSPDREVQN-DLMLQSNGSQYSPNEIREN---SPSVSPTANITAPFGLK--------PRSG--------SWCPEEVQGSLQAESSPRRPQLL---SRHVFLRPQRNLESIDPQFTIRRKMEQMREEKELVEQLRESIEMRLKVTLHEDLGAALMDGVVLCHLANHVRPRSVASIHVPSPAVPKLSMAKCRRNVENFLEACRKLGVPEEKLCLPHHILEEKGLVKVGTTVQALLDVT-------------------------------VTKALFT----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2L9-1", "uniprot_id": "LRCH1_HUMAN", "id": "Q9Y2L9-1", "name": "Leucine-rich repeat and calponin homology domain-containing protein 1", "aln": "-MATPGSEPQPFVPALSVATLHPLHHPHHHHH--HHQHHGGTGAPGGAGGGGGGSGGFNLPLNRGLERALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLKVLIASNNKLGSLPEEIGQLKQ-LMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLSLVKFDFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQ-IKTADS--LYLHTMERPHLHQHVEDG--------KKDSDSGVGSDNGDKRLSATEPSDEDT-----VSLNVPMSNIMEEEQIIKEDSCHRLSPVKGEFHQEFQPEPSLLGDSTNSGEERDQFTDRADGLHSEFMNY-KARAEDCEELLRIEEDVHWQTEG--IISSSKDQDMDIAMIEQLREAVDLLQDPNGLSTDITERSVLNLY----------------------PMGSAEALELQD--------SALNGQIQLETSPVCEVQS-DLTLQSNGSQYSPNEIREN---SPAVSPTTNSTAPFGLK--------PRS--------------------------------------VFLRPQRNLESIDPQFTIRRKMEQMREEKELVEQLRESIEMRLKVSLHEDLGAALMDGVVLCHLVNHIRPRSVASIHVPSPAVPKLSMAKCRRNVENFLEACRKLGVPEADLCSPCDILQLD-FRHIRKTVDTLLALGEK--------------------------APPPTSALRSRDLIGFCLVHILFIVLVYITYHWNALSA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QG10-1", "uniprot_id": "A0A8M9QG10_DANRE", "id": "A0A8M9QG10-1", "name": "", "aln": "-MATLGPEPRPLS-QLPSAALQ--------------TNLSGLGSST------------NLPLNRGLERALEDAANSGFLNLSTRKLKEFPRTASN-YDLTDTVEADLSKNRLIDVPSEVCHLVSLETLNLYHNCIKSIPDTIISLQSLTCLNISRNQLSVLPACVCGLPLRVLNASNNKLNALPESIGQLTN-LMELDVSCNEITALPRQIVQLKSLRELNVHRNLLCVLPEDLADLPLVKFDFCCNKVSTIPVCYRKMTQLQSLQLENNPLQSPPAQICMKGKIHIFKYLAMEACRSDKMADA--LYLPVTDRLSLTRPSNGSTEDIDQHKKLDSDSGVGSDNGDKRLSATEPSDEDS-----LSLNVPMTNITEEEGLSKDDSSEHIS--------------GLTGDRSSSESLKDHLSYRDSALSSPFVNYIKGRGADFDEPLRIEEDTNWVSEQ--TAKVN--------MINQLKEAVEMLQDPNRVNMNSADLSGIKLYPVEMVAVDDSLNGQESDEGQATPKAPGECWEFQRKRQFILERARLEAQLACQQYALHMAQQGDVIGQEGAGDSCENQITMNEEKTPVSSPTLNS-PPFGLK--------PRSASPSVPCSTPPCPLPLTQAPPTDRDTPPSPAEGDMPSSVFFRTHKTLESVDPQFTMRRKMEQLREELELTEQLRESIESRLKVVLPEDLGCSLSDGVVLCHLVNHIRPRSVGSIHVPSPAVPKLSMAKCRRNVENFLDACRKMGVPESSLCSAYDVLQCN-LRPLWAVVAALLMVESTGTRHMEGKVEGGREKETEVKKLIPESTQTPPPSWQIWDLIGSSLLHVFCLVMLFVAYSWSEFK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q960C5-1", "uniprot_id": "LRCH_DROME", "id": "Q960C5-1", "name": "Leucine-rich repeat and calponin homology domain-containing protein", "aln": "MAATVYQRLHSVAVGVGSAAGSAIGSGSASLPGSGTGSGSGIGHAGNTSSSTSSALLSHSQLTRSLERILEEAHFSGELILTNRKLKDFPRTGTK-YSLTDTVIADLSRNRFAELPEEVTTFAFLETLLLYHNTIRSIPESVKQLSSLTYLDLRSNQLSSLPREICFLPLQVLLVSNNRLTSLPDELGRLDQTLTDLDASYNQLANLPARLGELRSLRSLSLRSNHLLYLPRELTCLSLISLDVSNNKIASLPLEIRHMSTLVELQLENNPLTSPPASLCMRGLVHVFKFLETQATKDEKGSRSGGNYDGYTTLRRAPRHNSSG--------NVLEASTTGSTNNQRRHQVDSGYNTSDGLDKRWSHDAPTKSKTDSPLHCVSNSTAATLPRTLPSAVHSQADLMDASLTSSTSTIVDESLTLSPTASPCKLSYAHSNSSSNGSSPDQDDDIMLDHQERTVHHANGRSGKGLGNIQTYKEYKEALKQQRNQEISVYKQKHPNAN--------HSPNDDEDLSPSPPSISNGSSSNTLPKSIMKQNSNQIGHNGNGNGSANGNGVDDVVIPKKPIQKVIPSRITEIKPASTSDIRSANSSDCLGYVKPQSPMKNGTSKFNTSNGGGVQTTVGIVSSTTIKSPVSSTTKLGTVKTHRSVTWNHDIPAEKLSFTMRREFDRQREETELMSQLRTIIETRLKMTLPVDIASALTDGVILCHLANYVRPRSVASIHVPSPGVNKLTMARCRRNVDNFLEACRRIGVDENLICCAADVLEGKGAVQVAITVGELFRLHGN-------------------------------GGCGSGNSSGAATPTKSPTRTTRATMSPTPLA-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** . :.. : :: .. * . : *.*.*** **:* ** * *: ****:**** : :.*:*** ****:**: ::* *: :. ** * **** *: **::: .*. ** *:: **** ** :* ***:** .***:* :**:.:*:* : * :**.* *::: ** :: :*:***.*.:: * * ** :*. *.*:.:*.. **: :*: *.*. * * ****** ****.:* :* :*:**:* :* : * : : * : ... : . * .** *.::* .. . : . * :.* .. :. .:: . : :. :.* : .. . . ::* : . *: :* *: . . . . : . ... : : : : . . : :. . ..* :. : * :* * . :: : : . .**:**:::: *** ** .*** ** ***: * *:..:* ***:****.*::*****.*******.* **:**:*****:***:***::** * :* . .:* . : .* *: : . ", "identical_positions": 194, "similar_positions": 188, "identity": "22.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1791", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O14776-1", "uniprot_id": "TCRG1_HUMAN", "id": "O14776-1", "name": "Transcription elongation regulator 1", "aln": "MAERG----------GDGGESERFNPGEL------------------RMAQQQALRFR-GPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPG---TPALPP---------TEEIWVENKTPDGKVYYYNARTRESAWTKPDG--VKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQ--VQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPP--HKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSE--------------KEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSN-HHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAK-------------------------------------------------------------------------------------------------------NLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDRRGPPPPPTASEPTRRSTK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CGF7-1", "uniprot_id": "TCRG1_MOUSE", "id": "Q8CGF7-1", "name": "Transcription elongation regulator 1", "aln": "MAERG----------GDGGEGERFNPGEL------------------RMAQQQALRFR-GPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMGAMPPPPGMMFPPGMPPGTAPG---APALPP---------TEEIWVENKTPDGKVYYYNARTRESAWTKPDG--VKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQAVGAPTPTTSSPAPAVSTSTPTSTPSSTTATTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSAPAPTATPVQTVPQPHPQTLPPAVPHSVPQPAAAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLDEKIKEPIKEASEEPLPMETEEEDPKEEPVKEIKEEPKEEEMTEEEKAAQKAKPVATTPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPP--HKKGLEDMKKLRHPAPTMLSIQKWQFSMSAIKEEQELMEEMNEDEPIKAKKRKRDDNKDIDSE--------------KEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSN-HHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAK-------------------------------------------------------------------------------------------------------NLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDRRGPPPPPTASEPTRRSTK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LU61-1", "uniprot_id": "A0ABK0LU61_RAT", "id": "A0ABK0LU61-1", "name": "Transcription elongation regulator 1", "aln": "MNNRQSYKDVGRTCQAEGTTNRGYNIMEIVDVFDDQEYWSLEMSTTSRMAQQQALRFR-GPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMGAMPPPPGMMFPPGMPPGTAPG---APALPP---------TEEIWVENKTPDGKVYYYNARTRESAWTKPDG--VKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQA-------------AQAQAQAQAQAQAQAQAQAQAQVQAQ------AVGAPTPTTSSPAPAVSTSAPTSTPSSTTATTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSAPAPTATPVQTVPQPHPQTLPPAVPHSVPQPAAAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLDEKIKEPIKEASEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVATTPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPP--HKKGLEDMKKLRHPAPTMLSIQKWQFSMSAIKEEQELMEEMNEDEPIKAKKRKRDDNKDIDSE--------------KEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSN-HHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAK-------------------------------------------------------------------------------------------------------NLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDRRGPPPPPTASEPTRRSTK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1PCM8-1", "uniprot_id": "A0A8M1PCM8_DANRE", "id": "A0A8M1PCM8-1", "name": "Transcription elongation regulator 1", "aln": "MAEHT--------------EAEGIGLAAN------------------SMSQQAALRFPPAVAPPAAPPARRQPLLSSPVPPYTLMRSPPPAARPPFTRLPFDP---SVPPPMGTPPLQ--VHSQRPPFMPPPGGSMPPPPGMIFPPGIPPSVAPAPTPAPALAPAPAPTPLVSTEEIWVENKSPEGKVYYYNARTRESSWTKPEG--VKVIQQADLCPLMMSQAAVAAAGGGSTAPSVSIPAASAVSG-----------------------------------------------------STNTLAAPSAGPAVVPSITAASP-----LLPTPATVPDVVEMPSVVTSAPS---SMPTPMPAVNQPT-----VSVAMTTGPPTLPVALSHTVPQPATTIPGFPPVMVPPFRVPLPAMPIPLP---------------------GMLPSMAPPLVPMMPPQMTIAG-PAGLPGALGTSDWAEFKTPEGKSYYYNKHTQETTWDKPEELRDTEKESEKVMDSVEEMMEAEI-LSMEDGSPQIDPPKEQKEELKEEEMTEEQKAAKKAKPVATTPIPGTPWCVVWTGDERVFFYNPTTRLSMWERPEDLLGRADVDKAIQAPP--HKRGLDNSHRL---------------ALVKDEQEFPVSEDAADEEPSKAKRRKVEEKMELDPE--------------KEAAMEAELKAARERAVVPQEARISQFKEMLLERAVSAFSTWEKERHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQVKDDFRKMMEESKLGVRTTFSEFAAKHARDSRFKAVEKMKDREAIFIEFMTAFRKKEKENSKNRGEKVKLDFFELLSD-YHVDIQQRWSKVKEKLETDPRYKAVETSAAREEFFKNYVERLAK-------------------------------------------------------------------------------------------------------NPSAEKEKELEKQARVEASLRERERTVQRFRSEQTKEIDREREQHKREEAVQHFKALLSDMVKSSDAAWSDTRRSLRKDHRWESSSLLEREEKERLFNEHIEALAKKKKEQFRQLLDDTTSITLTTSWKEVKKLIKEDPRCIKFSSSDRKRQREFDDYIKDKYITAKADFRTLLKENKFITYKSRKLMQESEQHLSDIEKILQKDKRYLVLDCMTEERHKLLMGYVEELERRGPPPPPTAFEPARRSTK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KFB8-1", "uniprot_id": "A0A0B4KFB8_DROME", "id": "A0A0B4KFB8-1", "name": "Transcription elongation regulator 1", "aln": "---------------MDASLEESMDSDGAS----------------SPITKTEATESPPEAGLNGNGSGSGSTSQETPNYGVAILKEKPSEAHRSK----------PFNAFSGRPIGEHTAQQQALQQQQLQQQQQPQQPQQQAPSGANGVTGPP--------------------EIWVETKAEDGRSYYYHAVTRETTWSRPDGPAVKIMTQAEVEEMAKRPAQAAKTEAKAGETSVEIPPVSSHLT-----------------------------------------------------SQPPPHLMSQPPPNAAAPLLSQPPPNVRQQPPPMFQPPGMQAPPGFGQPPFCMPPPTYGFPGGPAPAGAPWGVGIPPWQQQQHMQDKPAKSLIIKPGVIDPAVIARAAEWSEHRAPDGRPYYFHAG----------------RGESVWEKPQALRDMEAARMAAHSGVAPAVATAPSGLPPHLLPN-PMMHMPPGSGPPGFDPHAAFAAAAAAMKANSENTKAAQAAALEKEAKKAAEE-----KRKKEEEQKKAAASAKQTDKSRPVTSTPIAGTPWCVVWTGDSRVFFYNPSTRTSVWDRPEDLLNREDVDKAVNERPEQLKTPQEKSAEAEQKSGEEANQEQAKSQVQAQQLDQVQRVDADDDDDDEVIKIRTESESSVEEVPTKRVRMISKSKRAEDAALEAEQRAAKERALVPLEMRVTQFKEMLREKDVSAFSTWEKELHKIVFDPRYLLLTSKERKQVFEKYVKDRAEEERKEKRNKMRQKREDFRSLMEEARLHGKSSFSEFSQRNAKDERYRAIEKVRERESLFNEYIVEVRRREKEDKLLKKEQIRKDFLDMLRERHDIERHTRWYDIKKKFESDPRYRMVDS-MYREEYFEDYLHIMKEEKRKEREMREQRERERHRELKSDRKEKDKEKDKGRKDRGRSRSKDKDREHKSSKEKDKDKEEKSKSEKSKKRDTTPEEGEHREESEREERAGSDDSEVARQRENEAEQKQKEREKKLRVEQSIREREKEVQRTLAGHLRDRDKEREHHMREECIGHFTALLTDLVRTPDFTWKEVKRQLRKDHRWELIESLDREDRERKFNEHIDNLMKKKRERFREMLDEISTLQLTSTWKEIKKLIKEDPRYLKYNSD--KGEREFRDYIKDKTMTAKTSLRELLQECKFITHKSSDLIKENPNHLKEIQDILKNDKRYLVLDHMEEERNTIVLGFLEELNKRGPPPPPTASESTRRNK-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . ::: * . . . * ::: *. .: . .. . * * : * * * *.* ..* *****.*: :*: ***:* ***::*::*:* **:: *::: : * . .... . : . . * *. .: : * ... . :. *. ..* . . . *: * : .::: . .* . .. : . * * * : : . * . . * . * . . .: : : . :: : : : : : . :. : : *:* :::: : . * :.*::**:::**.***********.*******:** *:*:**:**:.* **** :: * * :. . : : : : ::: :. : : :.: .:: ::**:*** :**:***:** * *:.***:** *: ********** ************..*******::*** ******:**:**: * ::**:.:***::: :::****: ::*:*.*::*:**:::**::* *::. *::***:. : *::: **:::* : :.:: : ** .:*.*.*:****: *:: **: *::*:. : : * :*:** *:: *:* *:****: **: : : :: *:***:* ***.: :*.***:*:*::.* :*.:.:* ******** . *:**::*: *****: * ***:*:**::**: ::: **::***:**:****** :*:.*. * :*** :**:** :***:.:* **:* ****::* .*::*. :**.:::.**::******** : ***..:::.::::*::********* *.:**.. ", "identical_positions": 313, "similar_positions": 310, "identity": "24.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1796", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K7P2-1", "uniprot_id": "A0A0G2K7P2_RAT", "id": "A0A0G2K7P2-1", "name": "PHD finger protein 14", "aln": "MDRSSKRRQVKPLAASLLEALDYDSSDDSDFKVGDASDSEGSGNGS-EDPSKDSGEGSCSDSEENILEEELNEDIKVKEEQLRN-STEEIMSSDKQLIKMEKKEEEENGERPRKRKEKEKEKEKE------REKDKEKATVSDSAAASAAGTTPATSPPAV-TSPAVPTTTTSS-EEQVSEPKKWNLRRNRPLLDFVSMEELNDMDDYDSEDDNDWRPTVVKRKGRSASQKEGSDGDNEDDDDEGSGSEEDEN-----------DEGNDEDHSSPASEAGGKKKKSKVLSRNSADDEELTNDSLTLSQSKSNEDSLILEKSQNWSSQKMDHILICCVCLGDNSEDADEIIQCDNCGITVHEGCYGVDGESDSIMSSASENSTEPWFCDACKCGVS-PSCELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDIDKLRPVTLTEMNYSKYGAKECSFCEDPRFARTGVCISCDAGMCRAYFHVTCAQKEGLLSEAAAEEDIADPFFAYCKQHADRLDRKWKRKNYLALQSYCKMSLQEREKQLSP---------EAQARINARLQQYRAKAELARSTRPQAWVPREKLPRPLTSSASAIRKLMRKAELMGISTDIFPVDNSDTSSSVDGRRK-HKQPALTADFVNYYFERNMRMIQIQENMAEQKNIKDKLENEQEKLHVEYNKLCESLEELQNLNGKLRSEGQGIWALLGRITG-------QKLNVPAILRAPKERKPS------------------------------------------KKEGGT-QKTSSLPTVLYSCGICKKNHDQHLLLLCDTCKLHYHLGCLDPPLTRMPRKTKNSYWQCSECDQAGSSD--------------------------------------------------------MEAEMAMETLPDGTKRSRRQ--IKEPVKFVPQDVPPEPKKIPIRN---------------------------------------TRTRG--RKRSFVPEEEKHEERVPRERRQRQSVLQK---------------------------------------------------------------------------------------------------------------------KPKAEDLR----TECSTCKGTGENENLVSRMRLSEAKNRCDECRLCYHFGCLDPPLKKSPKQTGYGWICQECDSSSSKEDENEAGKKNASQELSMEQKNPKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D4H9-2", "uniprot_id": "PHF14_MOUSE", "id": "Q9D4H9-2", "name": "PHD finger protein 14", "aln": "MDRSSKRRQVKPLAASLLEALDYDSSDDSDFKVGDASDSEGSGNGS-EDPSKDSGEGSCSDSEENILEEELNEDIQVKEEQLKN-STEEIMPSDKQLIKMEKKEEEENGERPRKKKEKEKEKEKE------REKDKEKATVSDSAAASAAGTTPATSPPAV-TSPSVPTTTTTTTEEQVSEPKKWNLRRNRPLLDFVSMEELNAMDDYDSEDDNDWRPTVVKRKGRSASQKEGSDGDNEDDDDEGSGSEEDEN-----------DEGNDEDHSSPASEAGGKKKRSKVLSRNSADDEELTNDSLTLSQSKSNEDSLILEKSQNWSSQKMDHILICCVCLGDNSEDADEIIQCDNCGITVHEGCYGVDGESDSIMSSASENSTEPWFCDACKCGVS-PSCELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDIDKLRPVTLTEMNYSKYGAKECSFCEDPRFARTGVCISCDAGMCRAYFHVTCAQKEGLLSEAAAEEDIADPFFAYCKQHADRLDRKWKRKNYLALQSYCKMSLQEREKQLSP---------EAQARINARLQQYRAKAELARSTRPQAWVPREKLPRPLTSSASAIRKLMRKAELMGISTDIFPVDNSDTSSSVDGRRK-HKQPALTADFVNYYFERNMRMIQIQENMAEQKNIKDKLENEQEKLHVEYNKLCESLEELQNLNGKLRSEGQGIWALLGRITG-------QKLNVPAILRAPKERKPS------------------------------------------KKEGGT-QKTSALPTVLYSCGICKKNHDQHLLLLCDTCKLHYHLGCLDPPLTRMPRKTKNSYWQCSECDQAGSSD--------------------------------------------------------MEAEMAMETLPDGTKRSRRQ--IKEPVKFVPQDVPPEPKKIPIRN---------------------------------------TRTRG--RKRSFVPEEEKHEERVPRERRQRQSVLQK---------------------------------------------------------------------------------------------------------------------KPKAEDLR----TECSTCKGTGDNENLV----------RCDECRLCYHFGCLDPPLKKSPKQTGYGWICQECDSSSSKEDENEAEKKNASQELSMEQKTPKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94880-3", "uniprot_id": "PHF14_HUMAN", "id": "O94880-3", "name": "PHD finger protein 14", "aln": "MDRSSKRRQVKPLAASLLEALDYDSSDDSDFKVGDASDSEGSGNGS-EDASKDSGEGSCSDSEENILEEELNEDIKVKEEQLKNSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEKEKEKEREKEKEKATVSENVAASAAATTPATSPPAVNTSPSVPTTTTAT-EEQVSEPKKWNLRRNRPLLDFVSMEELNDMDDYDSEDDNDWRPTVVKRKGRSASQKEGSDGDNEDDEDEGSGSDEDEN-----------DEGNDEDHSSPASEGGCKKKKSKVLSRNSADDEELTNDSLTLSQSKSNEDSLILEKSQNWSSQKMDHILICCVCLGDNSEDADEIIQCDNCGITVHEGCYGVDGESDSIMSSASENSTEPWFCDACKCGVS-PSCELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDIDKLRPVTLTEMNYSKYGAKECSFCEDPRFARTGVCISCDAGMCRAYFHVTCAQKEGLLSEAAAEEDIADPFFAYCKQHADRLDRKWKRKNYLALQSYCKMSLQEREKQLSP---------EAQARINARLQQYRAKAELARSTRPQAWVPREKLPRPLTSSASAIRKLMRKAELMGISTDIFPVDNSDTSSSVDGRRK-HKQPALTADFVNYYFERNMRMIQIQENMAEQKNIKDKLENEQEKLHVEYNKLCESLEELQNLNGKLRSEGQGIWALLGRITG-------QKLNIPAILRAPKERKPS------------------------------------------KKEGGT-QKTSTLPAVLYSCGICKKNHDQHLLLLCDTCKLHYHLGCLDPPLTRMPRKTKNSYWQCSECDQAGSSD--------------------------------------------------------MEADMAMETLPDGTKRSRRQ--IKEPVKFVPQDVPPEPKKIPIRN---------------------------------------TRTRG--RKRSFVPEEEKHEERVPRERRQRQSVLQK---------------------------------------------------------------------------------------------------------------------KPKAEDLR----TECATCKGTGDNENLV----------RCDECRLCYHFGCLDPPLKKSPKQTGYGWICQECDSSSSKEDENEAERKNISQELNMEQKNPKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A286Y9D1-1", "uniprot_id": "PHF14_DANRE", "id": "A0A286Y9D1-1", "name": "PHD finger protein 14", "aln": "MDRGSKRRQVKPLADSLLDALDYDSSDDSDFKVGESSGSEGTGNGSDEEGSKESAAGSESDSD------------------------------------AAAASADEEGIDDLETKDLNQEDDEE---------EKVKESFSEETSSKETGGSSRSRKKGEKSSDMEPNGSATT-EENSAEPKKWNLRRNRPMLDFTTMEELNEMDDYDSEDDNDWRPTQGKKKGKASSGKEKEGSGEEDDDDDDGGSDEEDNEDDNDDDDDDDDEGNDDESSSSDSEEEGKKPKKKAGKNTGAFDEEETNDSHSTSHGKGNEDS-LLERPQTWSSQRMEHILICCVCLGDNSEDADEIIQCDNCGVTVHEGCYGVDGESDSIMSSASENSTEPWFCDACKNGVS-PSCELCPSQDGIFKETDAGRWVHVVCALYVPGVAFGDIDKLRPVTLTEMNYSKYGAKECSLCEDTRFARTGVCISCDAGMCRSFFHVTCAQREGLLSEAAAEEDIADPFFAYCKQHADRFDRKWKRKNYLALQSYCKVSLQEREKQLTP---------EAQARITTRLQQYRAKAELSRNTRPQAWVPREKLPRPLTSSASAIRKLMRKAELMGISTDIFPVDTSDISASVDGRRK-HKQPALTADFVNYYLERNMRMIQIQDNIVEQKNLKDKLESEQEKLHMEYDKLCESLEDLQNVNGQLRTEGQSIWSMMGGIVG-------QKLNVPAVLKAPKERKPS------------------------------------------KKEGGSPGKSSSLPAMLYSCGICKKNQDQHLLLLCDTCKLHYHLGCLDPPLTRMPKKTKNSYWQCSECDQASSD----------------------------------------------------------EADIAMETLPDGTKRSRRQ--IKGPIKFIPQEMSPEPKKPQVRG---------------------------------------TRTRGQKRKRMSICEEEKMEEPLPRERRQRQSTLQK---------------------------------------------------------------------------------------------------------------------KPKADDTR----TECTTCKGPGDNENLV----------RCDECRLCYHFGCLDPPLKKSPKQTGYGWICQECDTSSSKEEEAQEVEEESVNEETAEQEIPD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQZ8-1", "uniprot_id": "Q9VQZ8_DROME", "id": "Q9VQZ8-1", "name": "PHD finger protein 14", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKRARQPK-------------ITTQALLDFDLGESSSDSDFLPDIDN------------CSDGSKDESDGDGSSSDAS------------GGSDSESDSDAESEDSTLQLRQLLAETEPSPLENGINGVDHCAASSPAAPVVPRAPLQLSS--APAKRMCCVCLGERSDDVNEIVECDSCGVSVHEGCYGVS-DNVSISSTNSTCSTEPWFCEACRAGVSEPDCELCPNKGGIYKETDVGKWVHLICALYVPGVAFGEVEQLSSVTLFEMQYSKWGAKVCSLCENALFARTGVCIGCDAGMCKTYFHVTCAQVAGFLIEAHHEDDAADPFYAHCKVHSEKEMIKKRRRNYHTLRLNMMQRAREKEALAAEHETPAPHPNPAQARIQRKLLKIQHKYTRHKELKPTPWVPTQKMSRLLTTSASACRRLLAKAEIMSVDVQHLEQREAHINALTDIRKKWHIAPAFSVEFTAYYMDRIVRMDDFRQQQRELISHNAILSKDQDVLRAQYDTALEERKAVKATKDSLLTSIKSLHTALGQIAPNMTLPSVDLIAHPLPEAPPKTSTPTPPQRPISVPTAAALKMGVGFPLGHLGPPGSKMDSSRMLSTHAKQGKHSTSSASVEAAPSVSCGICKRSKDQHLLVKCDTCNLHYHLGCLNPPLTRPPKKSKQYGWQCSECCDKSEGSDAVTEISSGPRKSRTRFNKDGHLVYVDRYSLDDIPVAAVNVPKESHTKRALNKSLPAPAPEYIEDLTKSPKRPKLQSPCKTPINVPAENVTPTTDAAPVAASAATPAAAPTLPTPNTIVINLSGCEDSIDDSSGKLSRKGKRKDKHKNKHNLSSDTEKSIGKEHKRKRKKRAHLDESSTHLDNAGNTSGSTIKIIFKALRLPGEDAPESQYFYVPANAVRSVDEASRPTSVETVEDSVQGAEQALAPIVLPAASPQKVREPKETAASASVNPTPSPKRKVSPRKASPRKPRVGRPRVSNAKPNVEISCCVCSQTGKSNQVVT----------CDECHRHYHFACLDPPLKKSPKIRGYSWHCADCDPTDEDALPKK-------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :** : : * :* :*..*.*: * : .. ..*:.:..**..: . *.*.: .* .. . : .. . * :. . ... . : . . ** :******:.*:*.:**::**.**::********. :. ** *: * *******:**: *** *.*****.:.**:****.*:***::***********::::* .*** **:***:*** **:**:. ********.******:::******* *:* ** *:* ****:*:** *::: * :*:** :*: :*:* : ***** :* : : * :. :* .*** :*:.* **:**** *:*: ***:*.:..: : :. .: .* *:* * **::.:*. **::* :** ::::: * . : *..:*: *: :*:. *. : :: :..* :. :.: : :* *. : : * .** .*: *: : .:* .: ******:.:*****: ****:********:***** *:*:*: ****** : ... * :* *....**.: * * *::. .:::.* .. : .*. .*: : ** :.:*:::: *:: :*:..: : .* .*. .*..:::* ****: ***.*********** **.* * :**.:... : ", "identical_positions": 273, "similar_positions": 245, "identity": "21.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-18", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q501J6-1", "uniprot_id": "DDX17_MOUSE", "id": "Q501J6-1", "name": "Probable ATP-dependent RNA helicase DDX17", "aln": "-------------------------------------------------------------------------------MRGGG-FGDRDRDR--DRG-GFGARGGSGLPPKKFGNPGERLRKKKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVDHRGGGGGGGGRSRYR-TTSSANNPNLMYQDECDRRLR---GVKDGGRRDSTSYRDRSETDRASYANGSGYGSPNSAFGAQAGQYTYAQG-TYG------AAAYGTSGYTAQEYAAGTYGASSTASAGRSSQSSSQQ-----------FSGIGR-SGQQPQPLMSQQFAQPPGATNMIGYMGQTAYQYPPPPPPPPPSRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92841-4", "uniprot_id": "DDX17_HUMAN", "id": "Q92841-4", "name": "Probable ATP-dependent RNA helicase DDX17", "aln": "MPTGFVAPILCVLLPSPTREAATVASATGDSASERESAAPAAAPTAEAPPPSVVTRPEPQALPSPAIRAPLPDLYPFGTMRGGG-FGDRDRDR--DRG-GFGARGGGGLPPKKFGNPGERLRKKKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVDHRGGGGGGGGRSRYR-TTSSANNPNLMYQDECDRRLR---GVKDGGRRDSASYRDRSETDRAGYANGSGYGSPNSAFGAQAGQYTYGQG-TYG------AAAYGTSSYTAQEYGAGTYGASSTTSTGRSSQSSSQQ-----------FSGIGR-SGQQPQPLMSQQFAQPPGATNMIGYMGQTAYQYPPPPPPPPPSRK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QBS1-1", "uniprot_id": "F1QBS1_DANRE", "id": "F1QBS1-1", "name": "RNA helicase", "aln": "-------------------------------------------------------------------------------MRGSSSYGDRDRDRGRDRGPRFGSSRAVPPPPKKFGNPGDRLRKKKWDLDQLPKFEKNFYNENPEVHHMSQYDVEEYRRKREITVRG-SGCPKPVTNFHQAQFPQYVMDVLLQQNFKEPTAIQAQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVAFDYGKSSRIKSTCVYGGAPKGPQIRDLERGVEICIATPGRLIDFLEVGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLQDYVQINIGALELSANHNILQIVDVCMENEKDNKLIQLMEEIMAEKENKTIIFVETKKRCDELTRRMRRDGWPAMCIHGDKSQPERDWVLTEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLRQARDLVRVLEEARQAINPKLLQLVDT--GRGGGGGRMRYRGNNSSSNNPNLMYQDECDRRMRSGTGVNKGGRSSNNNNNNFSRDGRSGGSNRDERMSSSYRDRSRDGRNNYNSGPSYNNGGGEQFQSYGGGGGGGEQYGSRGAPSHPGGGAGGQDQPGPPQGLFGAPPPNPPQPGPGSGPGPGPQPLMSQQFPPPP--QPMMGFMGPGPYPFGSPPPLPPPRK-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***.. :******* *** **: . *********:*********.:********* *:*** ::: *:*:* ***:****** . ***** **:*:*********::*:*.***.**.***************************************************************** ****.**:****:******************************** ************************************************************:**.***:* ******************.***:************************:***:****************************.*****************************************************************:***:*::*****.*******:**** * ****** *** ..**:**************:* **:.*** .. . .: *. .*:. :* . *.. :: *: .* .* :*. :** .. .::*.: : . .:* ..*... * .* * .* *********. ** *:*:** .* : .*** *** : ", "identical_positions": 487, "similar_positions": 93, "identity": "64.42%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1809", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIK8-1", "uniprot_id": "CTSL2_RAT", "id": "Q5XIK8-1", "name": "CTD small phosphatase-like protein 2", "aln": "MKLRTRKASQQSSPIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGSTPKEERENPSKRSRIERDIDNNLITSTP-RTGEKPDKQLSRVRRKSPVNGEAGSYEMTNQHIKQNGKLE-DNPCSGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTS-TTSAN---GAAYS---NQAVQVRPSLNNGLEEAEETVTRDIPPLTAPVAPESG-----YSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG15-1", "uniprot_id": "CTSL2_MOUSE", "id": "Q8BG15-1", "name": "CTD small phosphatase-like protein 2", "aln": "MKLRTRKASQQSSPIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGSTPKEERENPSKRSRIERDIDNNLITSTP-RTGEKPDKQLSRVRRKSPVNGEAGSYEMTNQHIKQNGKLE-DNPCSGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTS-TTSAN---GAAYS---NQAVQVRPSLNNGLEEAEETVTRDIPPLTAPVTPESG-----YSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05D32-1", "uniprot_id": "CTSL2_HUMAN", "id": "Q05D32-1", "name": "CTD small phosphatase-like protein 2", "aln": "MRLRTRKASQQSNQIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGSTPKEERENPSKRSRIERDIDNNLITSTP-RAGEKPNKQISRVRRKSQVNGEAGSYEMTNQHVKQNGKLE-DNPSSGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTSTTTSTN---GAAYS---NQAVQVRPSLNNGLEEAEETVNRDIPPLTAPVTPDSG-----YSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4QNX6-1", "uniprot_id": "CTL2B_DANRE", "id": "A4QNX6-1", "name": "CTD small phosphatase-like protein 2-B", "aln": "MRLRMRKDSQQPTLARRACPARTKRKSSEVEECT---GE--SK---ALLSSIKKFIHGSSIKVEQDNPAKTS----HLSCELITSTPQRKNDLQRKSIYRARRRTSINGETTNHDTN----KPNGKLEVTEEVVSSPPRTTLLGTIFSPVFNFFSPANKN---ASNSPDQVVEAEEIVKQLEMEQVEEMPTCTATSREPLSVPLYTSAMTSAFRPPPTAHTPEQESENTPHPDLPPLTAPGSPATGGYVDASITVPAEGSYEEEWEVFDPYFFIKHVPPLTEEQLTRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELDDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQIYEIILFTASKKVYADKLLNILDPRKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDRNDSELLKLVPFLEKLVELNEDVRPHVRERFRLHDLLPPD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:** ** ***.. : .**:*** ***::. ** ** .*********:**: * *::**:* * .:. :****** * .: *.: *.**:: :***: .:: . * ***** : .************************* .*:**.*.**********:****:*:.*. :** : . *: ..*.: *: :. :*:*:* *:****** :* :* :. **.:***:*******:*************.*********************************:**********************************:***********************:************************************************************:**.*****:****************:*:***********", "identical_positions": 329, "similar_positions": 75, "identity": "68.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1820", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K369-1", "uniprot_id": "A0A0G2K369_RAT", "id": "A0A0G2K369-1", "name": "", "aln": "------MQKVLQTDDITN-----------NQVLRKRKRKRTETANSENANSASDKAQRDPYSGNAFLPGESSSDEETPLVELSKEELCN--KIESLKEKLRSIRKENSRLRQSLVMLQVLPQAVTQFEELVGMAETLLKSGGAMSTPASTLWRATNNSS-PDSFASLCS------NSNSTSSSPSSLKAEEEQQPGEKQ----FTIERWQIARCNK-SKPQKFINDLMQVLYTNEYMATHSLTGAKSSTSRDKVVKPAMNQNEVQEIIGVTKQVFPSADDVSIRRMIGQKLNNCTK----KPSVSKAPTSQEISRS------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PFX2-1", "uniprot_id": "BEND6_MOUSE", "id": "Q6PFX2-1", "name": "BEN domain-containing protein 6", "aln": "------MQKILQTDDITD-----------NQVLRKRKRKRTETANSENANSALEKAQRDPYSGNAFLPGESSSDEETPLMELSKEELCN--KIESLKEKLRSIRKENSRLRQSLVMLQVLPQAVTQFEELVGMAETLLKSGGAVSTPASTLWRATNNSS-PDSFASLCS------NSNSTSSSPSSVKAEEEQHPGEKQ----FTIERWQIARCNK-SKPQKFINDLMQVLYTNEYMATHSLTGAKSSTSRDKVVKPAMNQNEVQEIIGVTKQVFPSADDVSIRRMIGQKLNNCTK----KPNASKAPNSQDGILK------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SZJ8-1", "uniprot_id": "BEND6_HUMAN", "id": "Q5SZJ8-1", "name": "BEN domain-containing protein 6", "aln": "------MQKIVQTDEITN-----------TQAFRKGKRKRTETMDSENANSDMDKGQRDPYSGNAFLPGESSSEDEEPLAELSKEELCA--KIKSLKEKLTNTRKENSRLRQSLVMLQVLPQAVTQFEELVGMAEALLKGGGTMSTSASTLWRATNNSS-PDSFASTCS------NSNSNSSSPVSLKPEEEHQTDEKQ----FQIEKWQIARCNK-SKPQKFINDLMQVLYTNEYMATHSLTGAKSSTSRDKAVKPAMNQNEVQEIIGVTKQLFPNTDDVSIRRMIGQKLNNCTK----KPNLSKNLNSQDIK--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q933-1", "uniprot_id": "A0A8M9Q933_DANRE", "id": "A0A8M9Q933-1", "name": "", "aln": "MRRKTKAQRILDYENEEDEEEEQKPDCYSNGAQKRRKMYLSKEKAEENSSSEAGLQKLDVKVNELDCSSADLYTDSPPTSETEEAHYLQSYSKKELIAMVLCMQREMEDMKEQLRCLTACGKLARNLETLIEKTQVWSNGNNGISPGTPVSQGTTQAPGEPEAVIADVGSLPAVVNGQWLNQGPGPQKPHEATQNAHRDGLYTEFITPELLERCNTGTTAQKLTNDLLRGLYERECLASHSISGVVYNKRGQ--PKPALPTEEVQAILRTVQYFFPGKTDAEIKGYIRQKLQNEAKRLRKKPSLSGQYDSRDLNLPSPRSHLDMTDRN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:::: :: : . . :: * :: .**:.* : * .: .. . :. * * .: . . :.* : ::* . :::.* * . : . ::* *: ::. :... :*. :.. :*: .. *::. : . *.: ...* . *..* : .:: * : ***. :..**: ***:: ** .* :*:**::*. .. : ***: :*** *: ..: .**. *..*: * ***:* :* **. * *:: ", "identical_positions": 58, "similar_positions": 110, "identity": "17.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1825", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08851-1", "uniprot_id": "STX5_RAT", "id": "Q08851-1", "name": "Syntaxin-5", "aln": "MIPRKR--------YGSKNT------DQG---------------------------------VYLGL-------------------------------------------------------SKTQVLSPATAINSSSDIAPLPTPVALVPS-PPDTMSCRDRTQEFLSACKSLQSR--QNGIQTNKP-ALHATRQCSEFTLMARRIGKDLSNTFAKLEKLTILAKRKSLFDDKAVEIEELTYIIKQDINSLNKQIAQLQDFVR-------AKGSQSGRHLQTHSNTIVVSLQSKLASMSNDFKSVLEVRTENLKQQRNRREQFSRAP--VSALPLAPN-------NLGGGPIVLGGESRASRDVAIDMMDPRTS------QQLQLIDE----QDSYIQSRADTMQNIESTIVELGSIFQQLAHMVKEQEETIQRIDENVLGAQLDVEAAHSEILKYFQSVTSNRWLMVKIFLILIVFFIIFVVFLA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K1E0-1", "uniprot_id": "STX5_MOUSE", "id": "Q8K1E0-1", "name": "Syntaxin-5", "aln": "MIPRKR--------YGSKNT------DQG---------------------------------VYLGL-------------------------------------------------------SKTQVLSPATAISSSSDSTPLPTPVALVPS-PPDTMSCRDRTQEFQSACKSLQSR--QNGIQTSKP-ALHAARQCSEFTLMARRIGKDLSNTFAKLEKLTILAKRKSLFDDKAVEIEELTYIIKQDINSLNKQIAQLQDFVR-------AKGSQSGRHLQTHSNTIVVSLQSKLASMSNDFKSVLEVRTENLKQQRNRREQFSRAP--VSALPLAPN-------NLGGGPIILGAESRASRDVAIDMMDPRTS------QQLQLIDE----QDSYIQSRADTMQNIESTIVELGSIFQQLAHMVKEQEETIQRIDENVLGAQLDVEAAHSEILKYFQSVTSNRWLMVKIFLILIVFFIIFVVFLA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13190-1", "uniprot_id": "STX5_HUMAN", "id": "Q13190-1", "name": "Syntaxin-5", "aln": "MIPRKR--------YGSKNT------DQG---------------------------------VYLGL-------------------------------------------------------SKTQVLSPATAGSSSSDIAPLPPPVTLVPP-PPDTMSCRDRTQEFLSACKSLQTR--QNGIQTNKP-ALRAVRQRSEFTLMAKRIGKDLSNTFAKLEKLTILAKRKSLFDDKAVEIEELTYIIKQDINSLNKQIAQLQDFVR-------AKGSQSGRHLQTHSNTIVVSLQSKLASMSNDFKSVLEVRTENLKQQRSRREQFSRAP--VSALPLAPN-------HLGGGAVVLGAESHASKDVAIDMMDSRTS------QQLQLIDE----QDSYIQSRADTMQNIESTIVELGSIFQQLAHMVKEQEETIQRIDENVLGAQLDVEAAHSEILKYFQSVTSNRWLMVKIFLILIVFFIIFVVFLA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PD64-1", "uniprot_id": "A0A8M1PD64_DANRE", "id": "A0A8M1PD64-1", "name": "", "aln": "MNTRRR--------HGPKSS------QDG---------------------------------VYTGP-------------------------------------------------------SQTQSQLVQQLETP----LAVPAPIAPVP--DTFSMSCRDRTGEFQSVCKSLQGR--QNGAQPVRA-VNNAIQKRSDFTLLAKRIGRDLSNTFAKLEKLTILAKRKSLFDDKATEIDELTYIVKQDINSLIKQIAGLQELVR-------SRSAQNGRHLQTHSNTIVVSLQSKLASMSSDFKSVLEVRTENLKQQRSRQEQFSQTP--ASASAFHTN-------SFNN-SVLMQDDSKKT-DISID-MDLNSS------QQMQLVNE----RDSYIQNRADTMQNIESTIVELGSIFQQLAHMVKEQEETVHRIDANVEDTQLNVDLAHTEILKYFQSVSNNRWLLIKMFLVLVIFFIVFVLFMT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24509-1", "uniprot_id": "STX5_DROME", "id": "Q24509-1", "name": "Syntaxin-5", "aln": "MQTRRRLHQTDQQDYSSSSTYTIQEDQQGGAGAGSVGTGTAGGSVGLLAQSLVPPPTGHEAAIHIGDNYQSGDSISTPDYSDDKYGKAARQWNLRAFSGHALRTLSAAAAVVTGNQPGINNDSQSNYSYPASIPTSSQFYQSKEEPQETEPEPEIFVMAARDRTGEFANAIRSLQARNITRAVNIRDPRKAKQVQSYSEFMMVARFIGKNIASTYAKLEKLTMLAKKKSLFDDRPQEIQELTYIIKGDLNALNQQIARLQDISKD------QRRHTNGKHLVSHSSNMVLALQSKLASMSTDFKQILEVRTENLKQQKTRRDQFSQGPGPLAAHTVSPS-------TAKQGSLLLSEE---NQAVSIDMGSSDTTPLLSTQTQMAIYDD----SDNYVQQRAETMQNIESTIVELGGIFQQLAHMVKEQEEIVERIDTNVADAELNIEAAHGEILKYFQSVSKNRWLMIKIFGVLIFFFLFFVVFMS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q01590-1", "uniprot_id": "SED5_YEAST", "id": "Q01590-1", "name": "Integral membrane protein SED5", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MNIKDRTSEFQQSVLSYKKRNKNFREQQRERLQE--KESENFANN-TTGNGKSVSEFQKKASGIAHEISSTAQLLSKLAVLAKRKPMFNDNPVEIAELSFLIKRKIYAIEQSLVQLSQLKKTDVNGNTSNQSSKQPSAVQHSKNVVNLLNTQMKNISGSFKDVLEERQRLEMANKDRWQKLTTDTGHAPADDQTQSNHAADLTTYNNSNPFMTSLLDESSEKNNNSSNQGELSFPQNDSQLMLMEEGQLSNNVYLQERNRAVETIESTIQEVGNLFQQLASMVQEQGEVIQRIDANVDDIDLNISGAQRELLKYFDRIKSNRWLAAKVFFIIFVFFVIWVLVN-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: :.*. :* . :. . .. : :. *:* * *.::::.* *.**::***:*.:*:*.. ** **::::* .: :: :.:. *.:: : . . **..:* *:::: .:* .**.:** * . :: * :::: . .* . .: . : . *: : :: : *:*.* :::.***** *:*.:***** **:** * :.*** ** . :*::. *: *:****: :..**** *:* ::..**:.:*:. ", "identical_positions": 76, "similar_positions": 115, "identity": "15.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1826", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P12821-1", "uniprot_id": "ACE_HUMAN", "id": "P12821-1", "name": "Angiotensin-converting enzyme", "aln": "-----------MG-----AASGRRG-------------PGLLLPLPLLLLLPPQPALALDPGLQPGNFSADEAGAQLFAQSYNSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELY-EPIWQNFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSNMSRIYSTAKVCLPNKTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLQAGSSRPWQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYPEGIDLVTDEAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGWPQYNWTPNSARSEGPLPDSGRVSFLGLDLDAQQARVGQWLLLFLGIALLVATLGLSQRLFSIR-HRSLHRHSHGPQFGSEVELRHS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09470-1", "uniprot_id": "ACE_MOUSE", "id": "P09470-1", "name": "Angiotensin-converting enzyme", "aln": "-----------MG-----AASGQRGRW--------PLSPPLLMLSLLVLLLQPSPAPALDPGLQPGNFSPDEAGAQLFAESYNSSAEVVMFQSTVASWAHDTNITEENARRQEEAALVSQEFAEVWGKKAKELY-ESIWQNFTDSKLRRIIGSIRTLGPANLPLAQRQQYNSLLSNMSRIYSTGKVCFPNKTATCWSLDPELTNILASSRSYAKLLFAWEGWHDAVGIPLKPLYQDFTAISNEAYRQDDFSDTGAFWRSWYESPSFEESLEHIYHQLEPLYLNLHAYVRRALHRRYGDKYVNLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMVQKGWNATHMFRVSEEFFTSLGLSPMPPEFWAESMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTRVTMEQLATVHHEMGHVQYYLQYKDLHVSLRRGANPGFHEAIGDVLALSVSTPAHLHKIGLLDHVTNDIESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVARNETHFDAGAKFHIPNVTPYIRYFVSFVLQFQFHQALCKEAGHQGPLHQCDIYQSAQAGAKLKQVLQAGCSRPWQEVLKDLVGSDALDAKALLEYFQPVSQWLEEQNQRNGEVLGWPENQWRPPLPDNYPEGIDLETDEAKADRFVEEYDRTAQVLLNEYAEANWQYNTNITIEGSKILLEKSTEVSNHTLKYGTRAKTFDVSNFQNSSIKRIIKKLQNLDRAVLPPKELEEYNQILLDMETTYSLSNICYTNGTCMPLEPDLTNMMATSRKYEELLWAWKSWRDKVGRAILPFFPKYVEFSNKIAKLNGYTDAGDSWRSLYESDNLEQDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLDGPIPAHLLGNMWAQTWSNIYDLVAPFPSAPNIDATEAMIKQGWTPRRIFKEADNFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHPSAWDFYNGKDFRIKQCTSVNMEDLVIAHHEMGHIQYFMQYKDLPVTFREGANPGFHEAIGDIMALSVSTPKHLYSLNLLSTEGSGYEYDINFLMKMALDKIAFIPFSYLIDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPYVRYFVSFIIQFQFHEALCRAAGHTGPLHKCDIYQSKEAGKLLADAMKLGYSKPWPEAMKLITGQPNMSASAMMNYFKPLTEWLVTENRRHGETLGWPEYNWAPNTARAEGSTAESNRVNFLGLYLEPQQARVGQWVLLFLGVALLVATVGLAHRLYNIRNHHSLRRPHRGPQFGSEVELRHS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FFA5-1", "uniprot_id": "E7FFA5_DANRE", "id": "E7FFA5-1", "name": "Angiotensin-converting enzyme", "aln": "MNRGKRESRTPIGKQEHPAVNVSRRLLRKLLSQHSASQLRSIMLRAVVLLTLISWSAALKPEWMPGDYPPTEQGAERFVSDYNSTAEEVLYLSTEASWNYNTNLTDHNSQLQIEASLEEQAFTEAWGHKAKATFSESLMDTFTNPDLKKIIKKINVLEAANLAITDRELYNTILSQMDSIYSTAKVCPS--PEECWSLEPELQEIMATSRSYKRLLYAWEGWHNSSGVPLKSLYAEFVKISNKASQMDGFKDTGEYWRSWYESPTFKQDLENLFKQLEPLYQNLHAFVRRKLYDYYGPKYINLKGPIPAHLLGNMWSQTWNNIYNMMIPFPNRPNVDVTNTMIAKGYNATHMFRVAEEFFTSLGLLEMPPEFWDKSMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHVEYYLQYKDQPVSFRRGANPGFHEAIGDVLSLSVSTPKHLHSIDLLDQLTDDAESDINYLLKMALEKIAFLPFGYLIDQWRWSVFSGETPPDRYNADWWYLRTKYQGICPPTRRTEEHFDAGGKYHIPGNTPYIRYFVSFILQFQFHEKLCKEAGHTGPLHKCDIYKSREAGAVLEKVLKAGSSEPWTQVLQEALGTDKMDATPLMSYFLPVTTWLREQNEKTGETLGWPDFNWVPPIPEGYPEDIGKITDEMQAKQFLDEYNSTAEEVWNAYTESSWTYNTDITEAHKDNMLQKNLEMANHTKIYGLEARKYDTSDFQDESVKRILSKLSDLERAALSAEDLVEYNNLLASMETLYSVATVCKDKSNCLPLDPDLNKIMAESRDYDELLFAWQGWRNASGREIRDSYKRYVELANSAAKSNGHTDNGAFWRSLYETPTFEQDLEALWKDLEPLYLSVHAYVRRALYKKYGPERINLKGPIPAHLLGNMWAQTWSGIMDLVNPYPDATQVDATPAMIAQGWTPKRMFEESDRFFTSLGLLPMPPEFWNKSMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTVVTMDDLITVHHEMGHVQYFLQYKDQPISFRDGANPGFHEAIGDVLALSVATPKHLQSIGLLDKVEDNAESTINFLMSIALDKIAFLPFGYLMDQWRWKVFDGRISSSEYNKEWWNLRMKYQGLCPPVPRTEKDFDPGAKFHIPANVPYIRYFVSFVIQFQFHKGLCDAAGHKGPLHNCDIYQSKEAGKLLSDVMKMGFSKPWPEAMKIITGQPKMSVQPLMEYFKPLIEWLEKENEKNGDVLGWPEYDWTPYKLSTVVEESPKS-VNFLGLSVDAAGAAAGQWILLVLSIVFLLAVVFLAYRYSKTK---RLQNKS-----MSQMELK--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *.. * :: ::** . : **.* **::.. * **: *...***:** *:: *. *** ::**:* .*:: * **:* .* *:*.**:*** : *.: :.**:..*::** :..* .***.::.*: **::**:*. ****.*** . . ****:*:* :*:*:**** **:******:: *:***.** :*. :**:* : *.*.*** :*****:**:*::.**::::****** ****:*** *: ** :*:**:*********:**:*:*:***:*::***::**:***.**: :*:********:******* * ****** ******:************************** ***:** ********::******* **:****************:****** ***.*.***::*:* ***********************:*****.****.***.*** ***************. *.* *****.*:*:*. **********:******: ******: ****:****:* :*** *.:**:**.*.** :**:: :* * :** .*:.** **: **.***::.**.****: :* **:*:.***.*. *** :*.:*::**: *:: : * *:*:.* ***:** .. :*:*. :::*** ** .*:.:*..::*: ::***:.*:.:*:**.*..::* ***::* .*** **::.:* :..*: *:***.::** **.*::**:**:.**: ** * : :***: *. *: **:.* * ***:**: .:***** *:::*:****.:******:*:::**.: ***.*****************.* *** *:*.*..:*:* **: *****:*:*:*:* *********:**********************.******* ********* *.::**: .******:***:**** *:::*:************::****:***** *:.**.. .. * *****.:*******:**.**:*****:**** *:..:**:***.**:***********:: *****:***:*:.***:******:******:.** ****.****:**********: *: .**:*:*:******::*****:**...::.***** :** .**. :*: ****:*:*:* . : . .. *.**** ::. * .***:**.*.:.:*:*.: *: * . : *:. *::**: ", "identical_positions": 769, "similar_positions": 357, "identity": "57.52%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1830", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZUV2-1", "uniprot_id": "A0A8I5ZUV2_RAT", "id": "A0A8I5ZUV2-1", "name": "E3 ubiquitin-protein ligase SMURF2", "aln": "MGLGRDTRAPCVPRGVRPSSGALGAGDLAHNPAPETALPTTNPALQQAPPPSPPRPQEPTSGGGGGGGGGGSGPRTGFPQTRGRAEEEAAEHPPASADFAPSAPRPRGTEKGRPRRAARTGGGGGARRRRRGRPRLPLCCAARAEEAEVGGGGSSASRSLRGSWRRRSAHPGPSGPGGRGAGCSDPGPGRCGDSSAPRRRPSPAQPARPRAASAAAAAASPAAGDMSNPGG-RRNGPVKLRLTVLCAKNLVKKDFFRLPDPFAKVVVDGSGQCHSTDTVKNTLDPKWNQHYDLYIGKSDSVTISVWNHKKIHKKQGAGFLGCVRLLSNAINRLKDTGYQRLDLCKLGPNDNDTVRGQIVVSLQSRDR---------IGTGGQVVDCSR--LFDNDLPDGWEERRTASGRIQYLNHITRTTQWERPTRP--------------------------------------------------------------------ASEYSSPGRPLSCFVDENTPITGTNGATCG-------------------QSSDPRLA--ERRVRSQRHR------------------NYMSR-------------------------------------------THLHTPP------------------------------------------------------------------------------------------------------DLPEGYEQRTTQQGQVYFLHTQTGVSTWHDPRVPRDLS--NINCEELGPLPPGWEIRNTATGRVYFVDHNNRTTQFTDPRLSANLHLVLN------------------RQNQLKDQQQQQVVS-LCPDDTECLT--------------------------VPRYKRDLVQKLKILRQELSQQQPQAGHCRIEVSREEIFEESYRQVMKMRPKDLWKRLMIKFRGEEGLDYGGVAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWILENDITGVLDHTFCVEHNAYGEIIQHELKPNGKSIPVTEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKTFDEKELELIICGLGKIDVSDWKANTRLKHCTPDSNVVKWFWKAVELFDEERRARLLQFVTGSSRVPLQGFKALQG---AAGPRLFTIHQ-IDACTNNLPKAHTCFNRIDIPPYESYEKLYEKLLTAIEETCGFAVE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A5Z6-1", "uniprot_id": "SMUF2_MOUSE", "id": "A2A5Z6-1", "name": "E3 ubiquitin-protein ligase SMURF2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNPGG-RRNGPVKLRLTVLCAKNLVKKDFFRLPDPFAKVVVDGSGQCHSTDTVKNTLDPKWNQHYDLYIGKSDSVTISVWNHKKIHKKQGAGFLGCVRLLSNAINRLKDTGYQRLDLCKLGPNDNDTVRGQIVVSLQSRDR---------IGTGGQVVDCSR--LFDNDLPDGWEERRTASGRIQYLNHITRTTQWERPTRP--------------------------------------------------------------------ASEYSSPGRPLSCFVDENTPITGTNGATCG-------------------HSSDPRLA--ERRVRSQRHR------------------NYMSR-------------------------------------------THLHTPP------------------------------------------------------------------------------------------------------DLPEGYEQRTTQQGQVYFLHTQTGVSTWHDPRVPRDLS--NINCEELGPLPPGWEIRNTATGRVYFVDHNNRTTQFTDPRLSANLHLVLN------------------RQNQLKDQQQQQVVP-LCPDDTECLT--------------------------VPRYKRDLVQKLKILRQELSQQQPQAGHCRIEVSREEIFEESYRQVMKMRPKDLWKRLMIKFRGEEGLDYGGVAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWILENDITGVLDHTFCVEHNAYGEIIQHELKPNGKSIPVTEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKTFDEKELELIICGLGKIDVSDWKVNTRLKHCTPDSNVVKWFWKAVEFFDEERRARLLQFVTGSSRVPLQGFKALQG---AAGPRLFTIHQ-IDACTNNLPKAHTCFNRIDIPPYESYEKLYEKLLTAIEETCGFAVE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HAU4-1", "uniprot_id": "SMUF2_HUMAN", "id": "Q9HAU4-1", "name": "E3 ubiquitin-protein ligase SMURF2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNPGG-RRNGPVKLRLTVLCAKNLVKKDFFRLPDPFAKVVVDGSGQCHSTDTVKNTLDPKWNQHYDLYIGKSDSVTISVWNHKKIHKKQGAGFLGCVRLLSNAINRLKDTGYQRLDLCKLGPNDNDTVRGQIVVSLQSRDR---------IGTGGQVVDCSR--LFDNDLPDGWEERRTASGRIQYLNHITRTTQWERPTRP--------------------------------------------------------------------ASEYSSPGRPLSCFVDENTPISGTNGATCG-------------------QSSDPRLA--ERRVRSQRHR------------------NYMSR-------------------------------------------THLHTPP------------------------------------------------------------------------------------------------------DLPEGYEQRTTQQGQVYFLHTQTGVSTWHDPRVPRDLS--NINCEELGPLPPGWEIRNTATGRVYFVDHNNRTTQFTDPRLSANLHLVLN------------------RQNQLKDQQQQQVVS-LCPDDTECLT--------------------------VPRYKRDLVQKLKILRQELSQQQPQAGHCRIEVSREEIFEESYRQVMKMRPKDLWKRLMIKFRGEEGLDYGGVAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWILENDITGVLDHTFCVEHNAYGEIIQHELKPNGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKTFDEKELELIICGLGKIDVNDWKVNTRLKHCTPDSNIVKWFWKAVEFFDEERRARLLQFVTGSSRVPLQGFKALQG---AAGPRLFTIHQ-IDACTNNLPKAHTCFNRIDIPPYESYEKLYEKLLTAIEETCGFAVE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A9JRZ0-1", "uniprot_id": "SMUF2_DANRE", "id": "A9JRZ0-1", "name": "E3 ubiquitin-protein ligase SMURF2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNQGV-RRNGPVKLRLTVLCAKNLVKKDFFRLPDPFAKVVVDGSGQCHSTDTVRNTLDPKWNQHYDLYIGKSDSITISVWNHKKIHKKQGAGFLGCVRLLSNSINRLKDTGYQRLDLNKLGPNDSDTVRGQIVVSLQSRDR---------IGSGGPVVDCSR--LFDNDLPDGWEERRTASGRIQYLNHITRSTQWERPTRP--------------------------------------------------------------------ASEYSSPGRPLSCLVDENTPIMTPNGAAGV-------------------PADDPRVQ--ERRVRSQRHR------------------NYMSR-------------------------------------------THLHTPP------------------------------------------------------------------------------------------------------DLPEGYEQRTTQQGQVYFLHTQTGVSTWHDPRVPRDLS--NVNCEELGPLPPGWEIRNTATGRVYFVDHNNRTTQFTDPRLSANLHLVLNP--SPNGSRAAVEAQSSSRPGQLKEQAQSVVSPGNLPEDPECLT--------------------------VPKYKRDLVQKLKILRQELSQQQPQAGHCRIEVSREEIFEESYRQVMKMRPKDLWKRLMVKFRGEEGLDYGGVAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKPITLDDMESVDPDLHNSLVWILDNDITGVLDHTFCVEHNAYGEIIQHELKPNGKSIPVTQDTKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKAFDEKELELIVCGLGKIDINDWKSNTRLKHCTPDSNIVKWFWRAVESYDEERRARLLQFVTGSSRVPLQGFKALQG---AAGPRLFTIHQ-IDASTNNLPKAHTCFNRIDIPPYESYDKLYDKLLTAIEETCGFAVE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V853-1", "uniprot_id": "SMUF1_DROME", "id": "Q9V853-1", "name": "E3 ubiquitin-protein ligase Smurf1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNKLDYPRRNGTHKVRITILCARNLARKDLFRLPDPFAKVQVDGTGQVYSTEISKSSLDPKWNAHYDLFLGIGDAITITVWNQRKIHK--GSGFLGCVRIPAFNIQSLKGAGFQRLDLGKLSPDDDELVRGQIIISLLSKDGPSSGNPLAIVGPSGDVRGPSEDDSSEDSLPEGWEERRTDNGRVYYVNHATKSTQWDRPRQPGVVGSSHATSPQQRHNTHNGNSGDRQAPAGPTRSTTCTNLMNNGHRSRDLSVTASDERRHSTEILSSVGKENTSPTTPVSATTTPGKKTSSSNSSSAGGRTLEQRPTNEPATPTSSTTSASVRLHSNDNHVKTPKHQTNGHAPPESTPTSPTGQQNYVNGNAQNGSTSGNGSGQAAQPQSASNGWTQEDAATTTSPSTTTSPPRHSQSPPTPNISPPASVTPSANGNVHSPNANSTPAGSGGGSRSYTAATPGQRSQRRSSRQQGEESSTRRRSSRGTRNGGTSGGGGGGGSGQRYASAAIAAANQAARPFLDLPPGYEMRTTQQGQVYFYHIPTGVSTWHDPRIPRDFDTQHLTLDAIGPLPSGWEQRKTASGRVYFVDHNNRTTQFTDPRLSGSILQMIRRGTVPPTSAANAGTPAPPSATPATPSAAAAVPPQATPASNATPTTLTTTTNPPHRIVPDLPQGLLEGADLLPKYRRDLVGKLRALRTELQTMQPQSGHCRLEVSRNEIFEESYRLIMKMRAKDMRKRLMVKFKGEEGLDYGGVAREWLHLLSREMLNPQYGLFQYSRDDHYTLQINPDSGVNPDHLSYFHFVGRTLGIAVFHGHCLDGGFTTPFYKQLLNKPITLGDIEGVDPDLHRSLTWMLESNISGIIESTFSVENNSFGALVVHELKPGGASIPVTEENKREYVKLYVNYRFMRGIEQQFLALQKGFCELIPSHLLRPFDERELELVIGGISSIDVNDWRNNTRLKHCTNETTQVLWFWQVVESYSSEMRARLLQFVTGSSRVPLQGFRALQGSTGAVGPRLFTIHLTADVPTQNLPKAHTCFNRIDLPPYETYQLLCDKLTQAVEETCGFAVE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.: . ****. *:*:*:***:**.:**:********** ***:** :**: :.:****** ****::* .*::**:***::**** *:*******: : *: **.:*:***** **.*:*.: *****::** *:* :*..* * . *. ::.**:******* .**: *:** *::***:** :* ..* :** *:*. . .. .*.:: : . *: :.:*:: :*: **:. * ::** *** *** ********** * **********:***:. ::. : :****.*** *:**:*********************..: ::. . . * . * . * :*:*:**** **: ** **. ***:****:****:******** :****.**: ****:**:***************:***:***** ********** *********.***:********** :*:****** :***** *******.*.***.*:* ******.**.*:*:.:*:*::: **.**:*::* :: *****.* ****.::.*:***:****:**:**** ********* *:**.***:.***:****:: *:..**:.**: ******** ::. * ***:.** :..* *******************:**** *.******** *. *:*************:****:*: * :** *:*********", "identical_positions": 458, "similar_positions": 181, "identity": "35.56%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1833", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80UP5-1", "uniprot_id": "AN13A_MOUSE", "id": "Q80UP5-1", "name": "Ankyrin repeat domain-containing protein 13A", "aln": "-----MSSARDTSSRFPLHLLVWNNDYEQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSFIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFER------------TKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITRIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGDLATECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTADE--SQGVEGTPAEAVSEATN-----------FEVDQSVFEIPESYHIQD-----NGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHTHSYEAQYERAIQESLLTNMEGRCPGGLSESSRFDSDLQLAMELSAKELAERELRLQEEEAELQQVLQLSLTEK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IZ07-1", "uniprot_id": "AN13A_HUMAN", "id": "Q8IZ07-1", "name": "Ankyrin repeat domain-containing protein 13A", "aln": "-----MSSACDAGDHYPLHLLVWKNDYRQLEKELQGQNVEAVDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENRQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLQKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSFIFKGEDNWAELMEVNHDDKVVTTERFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNIAFER------------TKSGFWGWRTDKAEVVNGYEAKVYTVNNVNVITKIRTEHLTEEEKKRYKADRNPLESLLGTVEHQFGAQGDLTTECATANNPTAITPDEYFNEEFDLKDRDIGRPKELTIRTQKFKAMLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLEFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEESVSQNVEGTQADSASHITN-----------FEVDQSVFEIPESYYVQD-----NGRNVHLQDEDYEIMQFAIQQSLLESSRSQELSGPASNGGISQTNTYDAQYERAIQESLLTSTEGLCPSALSETSRFDNDLQLAMELSAKELEEWELRLQEEEAELQQVLQLSLTDK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BG46-1", "uniprot_id": "A2BG46_DANRE", "id": "A2BG46-1", "name": "", "aln": "MLSASAASVEDFSLRFPLHVLVWENDYRKLETEIQTSNIEEVDPRGRTPLHLAVSLGHLESVRVLLRHGADVAKENGKNWTVLQEAVSTGDPEMVQLVLQRRDYLKASTALGGVPELLCKIRESPDFYMEMKWEFTSWIPLVSRVCPSDVCRIWKSGACLRVDTTLLGFENMTWIRGRRSYIFRGEDNCTELMEVNHEDEVVDTERFDLSREMEDVTLDSMQPAEQEVAKRLTTSIVNTYLDTKDIAFERNAIKTFTRSILRAKSGIWGWRSDRTEVVNGYEAKVFSVNNVNVVIRTRTEHLTDEEKARIKSERNVLESLLGTVEQQIGAQGDMTMEFATATNPTAITPEEYFNPNFDLQGRDIGRPIELTIRTQKFKGTLWMSEEHPLSLVEQVTPIIDLMARTSTHFARLKDFINLRFPPGFPVKIEIPLFHVLNARITFGSVNKCSTDEPLDTKTPASTPTPTEETCDNQAAAPAGPAPLFQVSPSVFLAPAHYHHRGGYRHANPRQYNPVNHDEELLQYAIHQSLLDSSVLNSQDTWSDSDGQATQSMTNRLSDGSGSEGVLVDLSDTTPSSSGSASSPDTDLRLAMELSARAQEEEEKRRKEEEEELERILQLSLTEK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. * . ::***:***:***.:**.*:: .* * :****** ************.****** ***:*** :.****:*********** ***:*** ::* ** ****** ** *:****::********:*****:**.********** **** ********:*******:**:* ** :*******:*.** **:****:*** :*** *:* .:** :***:.::** ****::**** :***:****:*::**********::****.*: : ******:*** * * :** *********:*:*****:: * **..*******:***: :***:.****** **********. ***.**.******** **********:*****:***:* ************************.** *** : :: .* : : . * *:*. *** * *: :. * *: : :.* *::*:**:****:** :. . :...* : : : : .*.:*.. .. *.. ..:* *.**:*******: * * * :*** **:::******:*", "identical_positions": 367, "similar_positions": 129, "identity": "58.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1868", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q86TB3-1", "uniprot_id": "ALPK2_HUMAN", "id": "Q86TB3-1", "name": "Alpha-protein kinase 2", "aln": "MKDSEGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDDRDRGWKHETGTHEEERANQIDEKEHPYKEEESISPGTPRSADSSPSKSNHSLSLQSLGNLDISVSSSENPLGVKGTRHTGEAYDPSNTEEIANGLLFLNSSHIYEKQDRCCHKTVHSMASKFTDGDLNNDGPHDEGLRSSQQNPKVQKYISFSLPLSEATAHIYPGDSAVANKQPSPQLSSEDSDSDYELCPEITLTYTEEFSDDDLEYLECSDVMTDYSNAVWQRNLLGTEHVFLLESDDEEMEFGEHCLGGCEHFLSGMGCGSRVSGDAGPMVATAGFCGHHSQPQEVGVRSSRVSKHGPSSPQTGMTLILGPHQDGTSSVTEQGRYKLPTAPEAAENDYPGIQGETRDSHQAREEFASDNLLNMDESVRETEMKLLSGESENSGMSQCWETAADKRVGGKDLWSKRGSRKSARVRQPGMKGNPKKPNANLRESTTEGTLHLCSAKESAEPPLTQSDKRETSHTTAAATGRSSHADARECAISTQAEQEAKTLQTSTDSVSKEGNTNCKGEGMQVNTLFETSQVPDWSDPPQVQVQETVRETISCSQMPAFSEPAGEESPFTGTTTISFSNLGGVHKENASLAQHSEVKPCTCGPQHEEKQDRDGNIPDNFREDLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVAVSVASPEPTDTALTLENVCDEPRDREAVCAMECFEAGDQGTCFDTIDSLVGRPVDKYSPQEICSVDTELAEGQNKVSDLCSSNDKTLEVFFQTQVSETSVSTCKSSKDGNSVMSPLFTSTFTLNISHTASEGATGENLAKVENSTYPLASTVHAGQEQPSPSNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSAADTTATPASYSSIVSFPWEKPTTLTANNECFQATRETEDTSTVTIATEVHPAKYLAVSIPEDK--HAGGTEERFPRASHEKVSQFP-SQVQLDHILSGATIKSTKELLCRAPSVPGVPHHVLQLPEGEGFCSNSPLQVDNLSGDKSQTVDRADFRSYEENFQERGSETKQGVQQQSLSQQGSLSAPDFQQSLPTTSAAQEERNLVPTAHSPASSREGAGQRSGWGTRVSVVAETAGEEDSQALSNVPSLSDILLEESKEYRPGNWEAG--NKLKIITLEASASEIWPPRQLTNSESKASDGGLIIPDKVWAVPDSLKADAVVPELAPSEIAALAHSP-EDAESALADSRESHKGEEPTISVHWRSLSSRGFSQPRLLESSVDPVDEKELSVTDSLSAASETGGKENVNNVSQDQEEKQLKMDHTAFFKKFLTCPKILESSVDPIDEISVIEYTRAGKPEPSETTPQGAREGGQSNDGNMGHEAEIQPAILQVPCLQG---TILSENRISRSQEGSMKQEAEQIQPE----EAKTAIWQVLQPSEGGERIPSGCSIGQIQESSDGSLGEAEQSKKDKAELISPTSPLSSCLPIMTHASLGVDTHNSTGQIHDVPENDIVEPRKRQYVFPVSQKRGTIENERGKPLPSSPDLTRFPCTSSPEGNVTDFLISHKMEEPKIEVLQIGETKPPSSSSSSAKTLAFISGERELEKAPK--LLQDPCQKG-TLGCAKKSRERE-KSLEARAGKSPGTLTAVTGSEEVKRKPEAPGSGHLAEGVKKKILSRVAALRLKLEEKENIRKNSAFLKKMPKLETSLSHTEEKQDPKKPSCKREGRAPVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQRSAGDNSTVSFAIVQASPKDQGLYYCCIKNS-YGKVTAEFNLTAEVLKQLSSRQDTK---------GCEEIEFSQLIFKEDFLHDSYFGGRLRGQIATEELHFGEGVHRKAFRSTVMHGLMPVFKPGHACVLKVHNAIAYGTRNNDELIQRNYKLAAQECYVQNTARYYAKIYAAEAQPLEGFGEVPEIIPIFLIHRPENNIPYATVEEELIGEFVKYSIRDGKEINFLRRESEAGQKCCTFQHWVYQKTSGCLLVTDMQGVGMKLTDVGIATLAKGYKGFKGNCSMTFIDQFKALHQCNKYCKMLGLKSLQNNNQKQKQPSIGKSKVQTNSMTIKKAGPETP-GEKKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91ZB0-1", "uniprot_id": "ALPK2_MOUSE", "id": "Q91ZB0-1", "name": "Alpha-protein kinase 2", "aln": "MTDPGCPERRTLCFLSTLLSQKVPEKSDVVLRCMIAGQPKPEVTWYKNGQAIDLGGTVSSYEFFENQYIHLLHLSCCTQSDAAVYQVSARNCVGMICCSASLEVQCLQD-PQVSPDPGGGRDAAGECKTEIREEDSINHTDEKWNPCKKGE-------STADSFLDKFNHLSSPQIVARGDSGASNSENPQYIKETRQRMGQYNSNNMQENS-----FNSNNTAEKQDVSQLWTVNATVPGLVSDGLGYE-ESNESVSPSHQTPKVQKYISFSLPLPETTLGPYPEDSNSINMQPGPQVSSEDSDSDYELCPEITLTYTEEFSDDDLEYLECSDVMTDYSNAVWQRSLQGTDRVFLLESDDEEMEFNECGLGGCEHFFTEMGCGPQVSGGMWSMNVATGFCSYHSQPQEVRVRSSGTSGHSPLPLHSEMTLTLGPHQDETAKMTEPGRAPLPTAPEAVENDCSGIRGETRDNPEAGEEFSGDNLQTMDKVETEASVKPLSGGSDKTEVKQGLESLARERTDEKYPGSKKAALRPTRARRPGMKANTKK--QLLRDSAPKGTLDLLP-KEPTRQPLPGSYGQEPTHTEAGAPGWDSHFHA-EVCIPLPAEQDSKILRPPADPLSKEEDSSFEGGGALLNKLFEASQIPDRTDHLQMQIQETIGESSSLDQMLAFSVPAEESSTFAGATTHSVSNLSEINRENLSLAQYPGLESCPQSLQQEGRPNRDRDLPGALWAESACELSLLEDNEEEESQPPASVALPQGDGVPCREPEGLSDSFPQPTAPSLPLENVGSGSRVREAAGGVGCFEAGDQETCYATMDLLVGAPVDKYLPQEICPEDLELTEGQSEVCDLCSPD--KILAVLQTQGSEPPRSTDKRSQDGKSAEGLLFNSTFTWDTAKEASEDAVGETAADVENPPSTFSSTLPYSER--------GFGETQPLCSETISFVKDSEGSYRSSSLSIPAAIDTLASYSSDRECSKEQSAESTANVDCHQVTREMEGISTN--AAEVHEIKCHSVSVPQDNDFDVGADQVSCEARDEDNSQSLPDDDSQSGRSLSSSTGEATGETLVPAPSSAG-DHGHFSMPEGQGLCSR-ALQMDNQPVCQSQAMEGAHSRGLEEHFQEKGSGMKHGIRPQSTSHQVSLSANDFQEILPSIPTMQQETNVEPLEHSLADSREEIECSSDPRTSDLVVAEKTVGEDSHLVVSVPALPDILLGEKDDVGLGSWAVG--GKVKIITLEAPVFEIWPPELVRHPGYKEAEAGLTMPGRSWALSDILRAGATRSEPGALGGAAWVPSPQADALMALGANRDTWLGAAPDRQANCNCLSSQCLSQPRFLESSVDPVEDKELEVTDSPSEVSKTGEMEMPETLNEEQEETQQILRHPAVVNQSVNFPRILESSVDPIDDRGELEGVWPEKPEPSDSS----VEGNEFIVGNTCQRVDIQPASLQLPHPQDSGEIIPYEHTTNQNRVDGERAEAKTSLPDKAKAEAEAVVWQAQGPGEEGQGIPSVCSMSQTQDGGDRSLGEAGQRGTDETEVISPLSPLSSCLTGVTHTCVKAETNNSTGHIYGGSE-----PRTRQSVIPMKTEKGTIESKCGNHVRSSDDLTNTPCTSSPKGNVTRLSISHGLEELKSEKLQIAETKPLNSSDSPTMTLALISGECESEKDPKSLLRRDPCPKGSTLDSGKKSRDQQQKPVAAQVSKAPGDQSAMAGSEEGKKKQEASGSGHLTAGIKKKILSRVAALRLRLEEKENSRKN-SIVKKTPKFERSLSRTDEKRDPKRAPCKAEGKAPVLLKRIQAEMAPEHSGNIKLSCQFSEIHEDSTVCWTKDSKSIAQAKKSAGDNSSVSLAIVQAGQKDQGLYYCCLKNS-YGKVTAEFNLTAEVLKQLSSHTEYR---------GCEEIEFSQLIFKEDVFNDSYFGDHLRGQISTEELHFGEGVHRKAFRSKVMQGLMPVFQPGHACVLKVHNAVAHGTRNNDELVQRNYKLAAQECYVQNTARYYAKIYAAEAQPLEGFGEVPEIIPIFLIHRPENNIPYATVEEELIGEFVKYSIRDGKEINFLRRDSEAGQKCCTFQHWVYQKTSGCLLVTDMQGVGMKLTDVGIATLARGYKGFKGNCSMTFIDQFRALHQCNKYCKMLGLKSLQNNSQKPKKPIVGKGRVPTNATQVKTPESETPPAERKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QU13-1", "uniprot_id": "ALPK2_DANRE", "id": "F1QU13-1", "name": "Alpha-protein kinase 2", "aln": "------------------------------MTAKRVDMAAPDNLLFLDSDAVNSS--PASVPIEQNEPTHVLDN----QTDDSLRSMPDPHTNTALESTGLMPVPCQDETLETHSQHNEGENESSLVSTQHMDHTRLTEMTINDE--------------------KSNNWDFDISGVKENDNSTNLNPDLIHHAGTDSVMERN--------------LNDKQTDLNHKDETFGSLMSSEVLLLKENRQQEMSQDTNLHQCSSSESTG--IEYSQTANDAISDAMNSEQS---PDQPFSIASNDTDKTTSECSVQTCWDTVESAATSKTQPELHDDVKDVMCESFTT------------SQTLNIDYLSTDISVCLADLPETDSLNILT----PASTLLGILGKNNN----VLKTADVPINDSEMVQSINKDLASPNADISKTVFTQMDQNLLHVTDHNVKVLESNRADTVVDQYVFSENIGQEVSQASSHDEDLNSSVQSHDQQLSTANSEIEETSSEFHTQTCQDIHEGVIIAEEAMN--------------GHNTLPEMHDIADVTTSQTPIMKDPMIDEPSYLPDLHKADTPNVITTASTLSDTLETDDSIFETADVSVSD-------------CELIQTVTLKTVTTYETLLMMHDVGEDLTCCDFTTSAIEEPETSHPLSLDDLHESNTPNIPPHASALLDSLGMNKNFLETADVPVSDCEVIQTVTFETVTTYETFPVMHD---IAEDLTCCDFTTSETPKIEEPE---------TSHSLSLDDLNEANTPNILPHASALLESLG-----MNNNFLEAADMPVSDREIIHPVNKDLDSSSVEICTVVLTQ----TDPKEVQDSDLDEKETESNRIDDSIDG-MIDTKFSLDVSKLQPVCSN-DLSGTVIHSESLFSQSIPDTPQIG-----------EKYKNDLLQVISPPTPVTNEDLGNCSEEIDDACLKFTGTERDVEGDSELWLEPSQFLAGEEDEGAIFDKWGRSCSSSPPTTHPDNTKASDYTWRENISIDHNAEDWELTFPPVERWSS---SDSWASALSDWFQAVNTYPEDSFKSASTGSKLGMAIQDNILEQRTSSDNANNDEQTCLSLNLMQPDEPGQALERGLVKSDNTNGTVFKQGDKERLASCLDMDKDTTTMESQMSLLETSTPESHKADNNAVMETFNASLTHEFNAKLHGSLDISGKLLSAKREGNVLVEVTGGKVSQLGLVFEEERQSIFTSPSSSAYTRDKNLTGCVSNEERCHSSDVHLCICPSQSDSHVSSKAGHAEGNGSFLHSNIGNCTVKPYVEEN----------IPQFIMPFAPICTGNTFLHRSFLKEDRSQADLDLPDKKIINKINLKSNKKSSSSDDSSEDNFHTCPDQSLSSSSGDSDDPSITDSGR--KPAYSDTC-------------------DIGKELSKLLLLTGEHFMVSEDKRIAYVTLDLD---------------ESQHFGRFSLPNCEKQSKPDNMPHKTSKTSSDGKMRSKHKEKPDDKQQHGIQASKK------QDPQPQSQVKNEGAGCEDCPVAVIETIVITEKIIPKTQGK-----KKKKHVQHGTPKPENDAPTDVRSESRQKNVNGKAENLELKVASNSLNKPVAQPSGKTDITKKDSAQKVMSVRPK----VEPSMAKMDPAGVNATQKSSPIKLKADTFNTAKMENKTCTTDSLSTCLPSMLNDDIKRRRIADDLSRAVPIRTRPQLPAIFRQARKDGEDVTRRAYSEVVKQKNSTP------KEVVVPRVVSEIQADPVPADPQNISLWCQFSPIPPEATIKWTKEAAVLSEINKVEKEDGRFTLTIIKACSKDLGFYKCSLIVANISVSTSEYHLTSEVLMELVIPSHDQPAEPRVMEGDEENIQCSPLLFKEDFLSDQYFGKNQPASILTEKVHFGEGMHRKAFRTTLTEGNLPRFRPGHPCVLKVHNSISYGTKNNEELVQKNYSLAVEECHVQNTAREYIKAYNSVAKSAESFGDLPEIIPIYLVHRPSNDIPYATLEEELLGDFVKYSVKDGKEINLMRRDSEAGQKCCAFQHWVYTQTEGNLLVTDMQGVGMKLTDVGIATCKKGYKGFRGNCATSFIDQFKALHQCNRYCELLGLVSLQPKPKRTVAPPKPKTQPVPKKKTFGPVLNAKS------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . *: : :.:*:: . :. : :*: *:*. :.* :: .:. : : .:. : * * .: : .: ..: . .* :. .. : . .. * . . : . * ... . : * :*..: ::. :: : : . . : : .: . .. .. *.:* . :: :. : .::*:*:*. . *. * * * : . * * :.* : *: :::: . :. * :. .. :: . . *: . :.: :::: .. :.. :: . .*: * : .: * ..: : . :.:* . . .* .::: .. : . . * .: : .. * : : . :.. . .. . ..: .: . . : . *.:: . .: : :. * : . :... .:*. *::: : : : : . : * : :: : : * * . ** : . :* : :: . : : . : * : : . :. . .** * :*.*::: . . . :*: . . : * . : : * . : :* ... ::. : .: :.* *: . : .: ..* . :: :.*: : :: . : : . * :. ::.:: . : .: .:. .. . . . : . * : : . . . .* *. . . : . . . : .: :* : . *.: .: : : . : . . . . *:. . : :. . ::: : : : :* *. ::*: .. :: :. * :. . :: .: . * .. . . *. : ::: .: .:* : . . * .:: :: * : .* . * . : : : * . .: *. . . :. . : * .: :.. .:.: * . . : :.:. ..::.. ..: : : *.** . *: . : ** *:: :* :: . : :: . . . : *. : *. . : ..* .: . : *. : . :. . .. :.:*. . . . : ::* . : : : : . .. ..:. ..: :. *: : : . . .** .... : *.: . ** :*. : ::. . : * . ::. . ::. . : ...: . ***...:* : : *: :. .: * .::: * * .* ::..***: * .. *:.* ***: * ::*: ***:: ::: :: ::. .:::*::* ** *:* *.: : . *:*::**:*** :* . : . *:*: * *:****.: *.*** . ..* **::*****:******:.: .* :* *:***.*******::::**:**:**:*:**.**.:**:****** * * * : *:. *.**::******:*:***.*:*****:****:*:*****::******::**:********:****** :*.* ******************** :*****:***: :*****:******:**::*** *** : :: * * : .: . .. ", "identical_positions": 305, "similar_positions": 662, "identity": "13.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1873", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A7X8-1", "uniprot_id": "A0A8I6A7X8_RAT", "id": "A0A8I6A7X8-1", "name": "", "aln": "MLTRAGCSRDPGRGWGRGRGRGRGRGRGRGSLRAPAPWELTFDAVAEQAGCEPAAAPPPAAFRGAQERGRPRPQRGAAFLPYPRNPGAPGPEAGAPGDVTTRAGSAFGASGRLASRVSPAAAAAAAARQWNVVASTRDEMWSEGRYDYERLPRERVPPRSHPSDEFGYRWTRDDHSTSRQSDYRDMRDGFRRKSFYSSHYSRDRSPHKRDAPFF--RESPVGRKDSP---HSRSGSSVSSRSYSPERSRTHTFHQSQHRKSSRVGASYKRQNEATRGRGKERSIQSLKTSRDTSPSSSSAVSSSKALDKPSRLTEKELAEAESKWAADTLERSDENNLGEISEFEAGSAAPLFIDQTEEPESNTTDGTEMYEDSQLSSRSKAIASKTKEIEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIGER-----CVEELKHFITEYDNSTQDFGDPF--------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K2H1-1", "uniprot_id": "PPHLN_MOUSE", "id": "Q8K2H1-1", "name": "Periphilin-1", "aln": "-------------MWSEGR--------------------YDYDRLPRER------VPP---------RSHPSDGYHRVVNVVPKRP--PLLDKRPP----------------LLDKRPPLLARPDEGGYSRYYSHVDCRVCDEGR----SFSHDRRSGPSHSGDESGYRWLRDDHSTSRQPDYRDMRDGFRRKSFYSSHYSRDRSPHKRDAPFF--RESPVGRKDSP---HSRSGSSVSSRSYSPERSRTHSFHQSQHRKSSRVGASYKRQNEAIRGRGKERSIQSVKTSRDASPSSSSAVASSKALDKPSRLTEKELAEAESKWANETLEKSDESNLAEMNEFEAGSTAPLFIDQTEEPESNTVDGTELYEDSQLSNRSKAIASKTKEIEQVYRQDCETFGMVVKMLIEKDPSLEKSVQFALRQNLHEIGER-----CVEELKRFITEYDNSARDFGDPF--------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NEY8-1", "uniprot_id": "PPHLN_HUMAN", "id": "Q8NEY8-1", "name": "Periphilin-1", "aln": "-------------MWSEGR--------------------YEYERIPRER------APP---------RSHPSDGYNRLVNIVPKKP--------------------------------PLLDRPGEGSYNRYYSHVDYRDYDEGR----SFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFF--RESPVGRKDSP---HSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIESAGQTWQQVPPVRNTEMDHDGTPENEGEETAQSAPQPPQAPQPLQPRKKRVRRTTQLRRTTGAPDITWGMLKKTTQEAERILLRTQTPFTPENLFLAMLSVVHCNSRKDVKPENKQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GK96-1", "uniprot_id": "A0A8I6GK96_RAT", "id": "A0A8I6GK96-1", "name": "Periphilin-1 C-terminal domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------MWSSRSYDEGP-------------QNASSGESGLRKTRDDLSASRQHACGDKKDVYRRKCSSSSHYSKQQSPHKGASCFS--RKSGVDRKTSP---HSRSRS---SGRHSTKQSKLHSSHGSELRKSKHAHSSYKRCSEEKPEGGKKRPGQSLKTSRDTHPKSSSAVLSSEILNKLRRFDEKGLPKAAGKQAVKKPEMAEESDLPQISEFEV-------MDQTQEPESNKTDHTEFSDD-QVTNRRKAIVSKTKEIEQAYYQDCETFGMVVKMLVEKDPSLERSIQFALRQNLHEISER-----CVKELRQFIAEYDAAAS--------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9Q633-1", "uniprot_id": "A0A8M9Q633_DANRE", "id": "A0A8M9Q633-1", "name": "", "aln": "---MAFRRERNLREVYEDR-------------------FAPDRAGPYPRGGQGERRPPFGRPDEEFGRGFEYDNSRFYPNGAPRNYHGEDQRGYHG---------------------DGHHNFPNEHRGGPPGRRQEDFPYYRGPREEPHGGRQMDFRPSNRPGPPPNARVQGSYPGPRSMPGPDAGDDTLIQAIMNLDRGEERENVRRKAPFPPVRERSPARRDIPPSPHSRSGSSISSRSYSPERSKAHPFPPQQGK------------SLDSLPSLSAFPMENLHWRDPPHTPTVDGAKGYEEPFGPGRAPDKERPPGPSVSASR--DGSPHSSVSATKEDITS------VEVPTEEVPAPVDEASSVMDDFQERRAQAIAAKAREIEKVYRQDCETFGMVVKMLVSKEPSLEKHLQNPLKENLIEIRER-----CLEDLQHFIAELDEVVRQPEPAV--------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* . :.. . .*. * * :. . . ..::. : * *: *: * **** * * :*.::*: :. .: : . . . :.:: . . : ... . : * :* . . . * : : ...: .* . : . * . .. . * * :**.:*::***:.* *************:.*:****: :* .*::** ** . : ::. : * ", "identical_positions": 55, "similar_positions": 84, "identity": "10.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1902", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1Z7T0-1", "uniprot_id": "PKN_DROME", "id": "A1Z7T0-1", "name": "Serine/threonine-protein kinase N", "aln": "MSDSYYQGEYIKHPVLYELSHKYGFTENLPESCMSIRLEEIKEAIRREIRKELKIKEGAEKLREVAKDRRSLSDVAVLVKKSKSKLAELKSELQELESQILLTSANTAVNSNGQESITACIDPNGGFLVSGAVGGLGGGNTALEGGAPATANDKVLASLEKQLQIEMKVKTG--AENMIQSLGIG--CDKKLLAEAHQMLADSKAKIEFLRLRIIKVKQNREQADRLKAS-RQMIDEHGQTIGGNNSSQPQSLETTLEERIEELRHRLRIEAAVVDGAKNVIRTLQTANRAPDKKALQEAHGRLSESSRKLDLLRYS-LDLRRQELPADSPAAQQLKTELQIVQLSTSPAPVTYTSLQSGQAGILGGKPYQSVSSLGRCASVTGKLEVRLLGCQDLLEDVPGRSRRDKDNNS--SPGDLRSFVK--GVTSRSSSKSYSV-----KDETSIEIMAVIKLDNITVGQTSWKQCSQQAWDQRFSIDLDRSRELEIGVYWRDWRSLCAVKVLRLEEFID----DVRHGMALQLEPQG----LLFAEVKFLNPMISQKPKLRRQRMIFNRQQAKNISRAKQMNINVATWGRLLKRNAPNHVHMGSAGSGSSLTGSSPMVVGGSRDSESPISRTPSSDALVEPEPYTPGEQAQNLEFDPDAGINEHVETPGEYPDPAASGLSGMRPLSMHMQGISVLPPESPPVATGAAGRPNTLSLQMPGASKGQVIQGGRTAAPTTAPPPPPVLKATSTTPILDQEVIPQLGKLYVGSSQQQYAQQSSPIIQEPATPTIYGNSAAAGAPQFPQPAQRQEKQPPQQQPIYANQYELNVAKAAAAASVYSPSSSTTSNSNQQQQQQRRNVARGLQYRESGGLETGRAGKQPPNAGMLSMDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTDVFLEPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDVSNFDEEFTSEKAQLTPPKEPRHLTEEEQLLFQDFSYTAEWC---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E7F7I3-1", "uniprot_id": "E7F7I3_DANRE", "id": "E7F7I3-1", "name": "protein kinase C", "aln": "-----MSGVTLQSSALQGLAEG-----DLMDPEFQQRVEDAIALLRQEIQRELKIKEAAERLRRAVTNRKSAADVDGQLRASSRKLEQLHWELQELNARAMATQKENVMDDATSP------DPCHWEEVTSPLG-------------------SHVRTLKKQLTMELKVKQG--AENIIQTYTNSSVKDRKMLSTAQQMLQDSRTKIELLRMQIVKVTQARE------GE-RETTQQEGR---------PSETISPLELRVEELRHHLRIEAAVAEGAKNVVKQLGVR-KVQDRRALAEAQARLQESSQKLDLLRLS-LEQQLGELPQDHPKRAAIKEELTVG--SSPGIGLQRERLRSSSS---------ASSSLFKPASLTGRLEVRLMGCQDLLESVPGRCRVSNMSSAPGSPSDSKSLRMRTGLSTRSTNGKTTK-----TDELSSEISAVLKVDNKIVGRTHWRPLSKDAWNQSFSIELERSRELEIAVYWRDWRSLCAVKFLRLEDFLD----NQRHGMCLYLEPQG----TLFTEVRFINPVIERHPKLQRQKRIFPKEKGKNFLRAAQMNMNFATWGRLMMSVLP--------PCNSTITALSPPLPG--------------------SEPLSP-------------------------------------------------PSVSTPPSTGDS----------------AVVKLNFSEERPTKPP------------------------------------------------------------------------------------RLHLAQNPSADESLSGTPARVNSTEDRRVLQARPASQPTTQRQEG----------------MQMEDFNCISVLGRGHFGKVLLAEFKRTGKLYAIKALKKGDVVTRDEVDSLMCEKRIFETINASRHPFLVNLYGCFQTPDHVCFVMEYSPGGDLMTHIHNNIFSERQARFYSACVLLGLEFLHQNRIVYRDLKLDNLLMDSDGFVRIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDSNYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFMSPESVSVIQKLLQKNSEKRLGAGEQDANEVKKHRFFQGIDWEALLAKRVKPPFLPSIKTAADVSNFDEEFTRLKPVLTPPQTPFFLSAEQQEFFADFDFSALH----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8K045-1", "uniprot_id": "PKN3_MOUSE", "id": "Q8K045-1", "name": "Serine/threonine-protein kinase N3", "aln": "----------MEH---RKPGTG------------QRAPKDEKEMVRRAIQKELKIKEGMENMRRVATDRRHLGHVQQLLRASNRRLEQLHGELRELHAQVLLP----ASAEPVTS------EPQPRAEQS---------------------RARLSEALHRQLQVELKVKQG--AENMIHTCASGTPKERKLLAAAQQMLKDSQLKVALLRMKISSLESSGS-------------PEPGP-----------------DLLAEELQHRLRVEAAVAAGAKNVVKLLGGQ-RMQDRKALAEAQAQLQESSQKLDLLRLA-LELLLERLPPTHSLRSRVTQELWMAMLGNPQP----------------------LGTLVKPIALTGTLQVRLLGCKDLLVAVPGRSPMAVLAGS---PSES---------WLRTRSRQQRG-----GGELASEVLAVLKVDNRVVGQTGWGLVAEKSWDQSFIISLDRARELEIGVHWRDWRQLCGVAFLKLEDFLD----NACHQLSLSLVPQG----RLFAQVTFCEPVIERRPRLQRQRCIFSKRRGRDFMRASQMNLSMAAWGRLVMSLLP--------PCSSPNTASPPKGRP--------------------STAVCG-------------------------------------------------TPSAASPSNFLP----------------MKTLSKEDTKPPPKPP------------------------------------------------------------------------------------RLYL-QEP-APGTP-----CTKRPHMDPRPAVVPALAALSTRKPP-----------------RLQDFRCLAVLGRGHFGKVLLVQYKGTGKYYAIKALKKQEVLGRDEIDSLYCEKRILETVGRTGHPFLLSLLACLQTSSHACFVTEFLPGGDLMAQIHEDVFPEPQACFYLACVVLGLQFLHEKRIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFECIVSADVPCPHFLSVQGLELIQKLLQKSPEKRLGAGERDAEEIKVQPFFRTTNWQALLARTVQPPFVPTLCGPADLRYFEGEFTSLPPTLTPPVSQSSLTARQQAAFRDFDFVSEQFLES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P5Z2-1", "uniprot_id": "PKN3_HUMAN", "id": "Q6P5Z2-1", "name": "Serine/threonine-protein kinase N3", "aln": "----------MEEGAPRQPGPS------------QWPPEDEKEVIRRAIQKELKIKEGVENLRRVATDRRHLGHVQQLLRSSNRRLEQLHGELRELHARILLPGPGPGPAEPVAS------GPRPWAEQL---------------------RARHLEALRRQLHVELKVKQG--AENMTHTCASGTPKERKLLAAAQQMLRDSQLKVALLRMKISSLEASGS-------------PEPGP-----------------ELLAEELQHRLHVEAAVAEGAKNVVKLLSSR-RTQDRKALAEAQAQLQESSQKLDLLRLA-LEQLLEQLPPAHPLRSRVTRELRAAVPGYPQP----------------------SGTPVKPTALTGTLQVRLLGCEQLLTAVPGRSPAAALASS---PSEG---------WLRTKAKHQRG-----RGELASEVLAVLKVDNRVVGQTGWGQVAEQSWDQTFVIPLERARELEIGVHWRDWRQLCGVAFLRLEDFLD----NACHQLSLSLVPQG----LLFAQVTFCDPVIERRPRLQRQERIFSKRRGQDFLRASQMNLGMAAWGRLVMNLLP--------PCSSPSTISPPKGCPRT------------------PTTLRE-------------------------------------------------ASDPATPSNFLP----------------KKTPLGEEMTPPPKPP------------------------------------------------------------------------------------RLYLPQEPTSEETP-----RTKRPHMEPRTRRGPSPPASPTRKPP-----------------RLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAVGCTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHEDVFPEPQARFYVACVVLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSVQGLEFIQKLLQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLCGPADLRYFEGEFTGLPPALTPPAPHSLLTARQQAAFRDFDFVSERFLEP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P24583-1", "uniprot_id": "KPC1_YEAST", "id": "P24583-1", "name": "Protein kinase C-like 1", "aln": "-----------------------------------MSFSQLEQNIKKKIAVEENIIRGASALKKKTSNVMVIQKCNTNIREARQNLEYLEDSLKKLRLKTAQQSQGENGSEDNER-----CNSKEYGFLSTKSPNEHIFSRLDLVKYDCPSLAQRIQYMLQQLEFKLQVEKQYQEANTKLTKLYQIDGDQRSSSAAEGGAMESKYRIQMLNKALKKYQAINVDFDQFKHQPNDIMDNQQPKFRRKQLTGVLTIGITAARDVDHIQSPMFARKPESYVTIKIDDTIKARTKPSRNDRWSEDFQIPVEKGNEIEITVYDKVNDSLIPVAIMWLLLSDIAEEIRKKKAGQTNEQQGWVNASNINGG-----SSLASEEGSTLTSTYSNSAIQSTSAKNVQGENTSTSQISTNSWFVLEPSGQILLTLGFHKSSQIERKQLMGGLHRHGAIINRKEEIFEQHGHHFVQKSFYNIMCCAYCGDFLRYTGFQCQDCKFLCHKKCYTNVVTKCIAKTSTDTDPDEAKLNHRIPHRFLPTSNRGTKWCCHCGYILPWGRHKVRKCSECGIMCHAQCAHLVPDFCG-MSMEMANKILKTIQDTKRNQEKKKRTVPSAQLGSSIGTANGSDLSPSKLAERANAPLPPQPRKHDKTPSPQKVGRDSPTKQHDPIIDKRISLQTHGREKLNKFIDENEAYLNFTEGAQQTAEFSSPEKTLDPTSNRRSLGLTDLSIEHSQTWESKDD-----------LMRDELELWKAQREEMELEIKQDSGEIQEDLEVDHIDLETKQKLDWENKNDFREADLTIDSTHTNPFRDMNSETFQIEQDHASKEVLQETVSLAPTSTHASRTTDQQSPQKSQTSTSAKHKKRAAKRRK-----VSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVKPPYIPEIKSPEDTSYFEQEFTSAPPTLTP--LPSVLTTSQQEEFRGFSFMPDDLDL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: ::: * * :* .. . ::. ..: . :: : .* *. .*::*. : . . : :** .:::*: * : ::: : *. :*: :: :*. : . : :.:: : . . : :: : : . * *...:::: :: :. : *: . . : . :: ..::: .. . *. : : . : .: * :: : . .: : :.:: :: : : : .: . : . * . * : : * . . : * :: : : *: : : .: :.. .::: . : . . . . . : . . : : : : . . :::* : ***:*:****:* : : ..: ***.*** ::: ..:::* .**::: **** .* .:** .: *. *: ***** ::: : : :* ** * *:*.*:::*:: ::******:*:*: .:*.::***:****: : :*:**.********:***:*.: **:*****.:***:::**: :.**.** *:***:.*:. : * :: : : .:: ** * .*:***:. :**::: . **: :: :* ::**::* : * *: *** . *** *: :* * .*.: . ", "identical_positions": 145, "similar_positions": 270, "identity": "11.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1904", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1L0-1", "uniprot_id": "PK3CB_RAT", "id": "Q9Z1L0-1", "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "aln": "MCFRSIMPPAMADTLDIWAVDSQIASDGSISVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAE-KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEDKIQSLVGLSWIDWLKHTYPPEHEPSVLENLEDKLYGGKLVVAVHFENSQDVFSFQVSPNLNPIKINELAIQKRLTIRGKEEEASP-CDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAIEAAINRNSSSLPLPLPPKK----------------TRVISHVWGNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCKTVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQTNPYAENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASGDSANVSSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALDNRRIGQFLFWHLRSEVHTPAVSIQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAMKLN--RAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCRYMDSKMKPLWLVYSNRAFGEDAVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BTI9-1", "uniprot_id": "PK3CB_MOUSE", "id": "Q8BTI9-1", "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "aln": "------MPPAMADNLDIWAVDSQIASDGAISVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAE-KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEAKIQSLVGLSWIDWLKHTYPPEHEPSVLENLEDKLYGGKLVVAVHFENSQDVFSFQVSPNLNPIKINELAIQKRLTIRGKEDEASP-CDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAIEAAINRNSSNLPLPLPPKK----------------TRVISHIWDNNNPFQITLVKGNKLNTEETVKVHVRAGLFHGTELLCKTVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQTNPYAENATALHITFPENKKQPCYYPPFDKIIEKAAELASGDSANVSSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALDNRRIGQFLFWHLRSEVHTPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLS--RAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYSSRAFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42338-1", "uniprot_id": "PK3CB_HUMAN", "id": "P42338-1", "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "aln": "MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE-KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEHEPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDEVSP-YDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRALPHFILVECCKIKKMYEQEMIAIEAAINRNSSNLPLPLPPKK----------------TRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHVKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKEILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLN--RAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F251-1", "uniprot_id": "E7F251_DANRE", "id": "E7F251-1", "name": "phosphatidylinositol-4,5-bisphosphate 3-kinase", "aln": "------MPPAKTDQLDLWA-ESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYPLFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERLLDSKIGVLIGKGLHELDALQDQEVKDFRSKMKRISEEKMQQMQMMSWGQWLRSSYSPQLDTSSLDNLIERHEG-IIKITMHYDQSQDTASLKVSLNCTVSEVMDHALKKWQTTHGPEEDIGARSNYVLRVSDRLEFLFEDYPLIQYKYIRACLSTGENPHLTVVHFDIVKSMFEKEIATVGSVLARKTSNPPLPLPPKKRQTTVRTSSMSASQLPQQLHTCVWKVHSLFRINLVKANKVNAEDAAKIQVRAGLFHGTELLCKTAVSNESSSRSEHVWNKTLEFDIPVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMSMGRGGKKFYIELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVSCLKDMSDDELLQYLLQLVQVLRYEPYYDCSLSRFLLERAQTSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALNKLKAVNELIKLGTIKTKTKQAHLKEAMMSCLRQTGFIETLSDLHSPLNPNILLAGVSVEKCKYMDSKMKPLWIVYNNKLLGGETVGIIFKNGDDLRQDMLTLQILKLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQEGKTGNTEKFGNFRQYCEEAYMILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **** :* **:** :* : .*. : ************:*****:**.:** :***:.:.**:*.** :::.:** ****:**:**********************:**.*. .* ***************:*:*:* **::** **:::** *: .: :** :**: :*.*: :.* :** :: * : :::*:::.**. *::** * . :: : *::* * :* *:: .. :***:**.*:*::* *:****::*** *: . **: :*. :*.*:*:*: :: :.: *::*. ******** :: : :* :. *:* ***.**:*:*::.*::*************** **.* *.:.:*:**: ***** :************:***:****.::***. : .**************:*********::***::**:***.**************:**:*****:**** **:.*** ..** :*.****:*****:*....: .****** ****::*********** ******* **** ***********:**.* **:*************.**:****************:**.**::***:** **********:***: **:********* .*:**:*********:: ****::*.:********.: *::**.**********::*.****.::* . :*: **** :**:*:.: *:****:***** ::*: : ****:**********:**..: :* ::**:****************:*:*********.****::*********:********:::***:** .***:**:*************: **** **:***************:***************:.********************************:*******:**********.*** **:**:***::************************************::*******:******************** * : ", "identical_positions": 714, "similar_positions": 242, "identity": "65.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1923", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AAD8-1", "uniprot_id": "A0A8I6AAD8_RAT", "id": "A0A8I6AAD8-1", "name": "Sorting nexin-4", "aln": "MERVPPDPEKLLQPAPLEPLGGPGAVLEAAVGEETEGTREDVSGADTMTGNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYLIETRSVEHA-DGQSVLTDSLWRRYSEFELLRNYLLVYYPHVVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRVASHPVLCRDKIFYLFLTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTELRQYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDV-----------YASSIDDILEDEEHYADQLKEYLFYAEALRAVCRKHELMQYDLETAAQDLASKKQQCEELATGTVRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNRDLKEALISYAVMQISMCKKVASPGIYCVSKFVPVYNLCLKVCTTT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YJ2-1", "uniprot_id": "SNX4_MOUSE", "id": "Q91YJ2-1", "name": "Sorting nexin-4", "aln": "MEQAPPDPEKLLQPGPLEPLGGPGAVLEAAVGEENEGTREDGSGVDTMTGNNFWLKKIEISVSEAEKRTGRNAVNMQETYTAYLIETRSVEHA-DGQSVLTDSLWRRYSEFELLRNYLLVYYPHVVVPPLPEKRAEFVWHKLSADNMDPDFVERRRVGLENFLLRVASHPVLCRDKIFYSFLTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTELRHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDV-----------YASSIDDILEDEEHYADQLKEYLFYAEALRAVCRKHELMQYDLETAAQDLAAKKQQCEELATGTVRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNRDLKEALISYAVMQISMCKKG-----------IQVWTNAKECFSKM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95219-1", "uniprot_id": "SNX4_HUMAN", "id": "O95219-1", "name": "Sorting nexin-4", "aln": "MEQAPPDPERQLQPAPLEPLGSPDAGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYLIETRSVEHT-DGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDV-----------YASSIDDILEDEEHYADQLKEYLFYAEALRAVCRKHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNRDLKEALISYAVMQISMCKKG-----------IQVWTNAKECFSKM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U012-1", "uniprot_id": "A0AB32U012_DANRE", "id": "A0AB32U012-1", "name": "", "aln": "MADSGSEDIAVIGNTDLTPSESQNNLKNTMVEKGTS-----------------LLKKMEISVAEAEKRTGKNAVNMQETYTVYLIETRPVDAASEGTSPVPDSLWRRYSEFELLRNYLLVTYPFVVVPPLPEKRAEFVWHKLSADNMDPDFVERRRVGLENFLLRVASHPVLARDNIFYLFLTEEKAWKETVFETGFQAKADSRIKALNATFRVKNPDKRFAEMKHYGDELQAVVSQLLRVRARAADRFYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDACLQQQADMHARYAASIDDILEEEEHYADQLKEYLFYADALRAVCRKHELTQYELETAVQDLSSKKQQREELATGTVRTFSLKGMTSKLFGQETPEQREAKLKMLETQIEEGEEMVKDRNVECEEFVKGAWTDIERFKEQKDHDLREALISYAIMQISMCKKG-----------IQVWNNAKECFSKM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .: : * * . . : * : . ***:****:*******:**:*******.******.*: : :* * :.**************.**** **.:*******************************:********:****:*.**:*** ***:* ***** ***** *****:****************:::::*.****:*:*:*******.***:************************************. **:*******:***************:*********** **:** *.***::**** ***.*************:*************::*:** **:***: :*.:*:* .****.**:*********::**:*******:******** : *:. . : :. ", "identical_positions": 313, "similar_positions": 73, "identity": "66.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1927", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UJV9-1", "uniprot_id": "DDX41_HUMAN", "id": "Q9UJV9-1", "name": "Probable ATP-dependent RNA helicase DDX41", "aln": "MEESEPERKRARTDEVPAGGSRSEAEDEDDEDYVPYVPLRQRRQLLLQKLLQRRRKGAAEEEQQDSGSEPRGDEDDIPLGPQSNVSLLDQHQHLKEKAEARKESAKEKQLKEEEKILESVAEGRALMSVKEMAKGITYDDPIKTSWTPPRYVLSMSEERHERVRKKYHILVEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQEVEYVKEEAKMVYLLECLQKTPPPVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQVLHCGDESMLDIGGERGCAFCGGLGHRITDCPKLEAMQTKQVSNIGRKDYLAHSSMDF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91VN6-1", "uniprot_id": "DDX41_MOUSE", "id": "Q91VN6-1", "name": "Probable ATP-dependent RNA helicase DDX41", "aln": "MEDSEPERKRARADEATAGGSRSEDEDEDDEDYVPYVPLRQRRQLLLQKLLQRRRKGATEEEQQDSGSEPRGDEDDIPLGPQSNVSLLDQHQHLKEKAEARKESAKEKQLKEEEKILESVAEGRALMSVKEMAKGITYDDPIKTSWTPPRYVLSMSEERHERVRKKYHILVEGDGIPPPIKSFKEMKFPAAILRGLKKKGILHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQEVEYVKEEAKMVYLLECLQKTPPPVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQVLHCGDESMLDIGGERGCAFCGGLGHRITDCPKLEAMQTKQVSNIGRKDYLAHSSMDF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9QFV1-1", "uniprot_id": "E9QFV1_DANRE", "id": "E9QFV1-1", "name": "", "aln": "-----------------------------------------------------------------MGS----------LGVVSALVLLSCGLLISVSAIPAIQGS-------ELDYTETTCLDSDLS--LSCDDGVIFVKSARFGWRSTR--------------------LCGPGRP---------HFETDPARCLR---EIPIIPKWCNGQATCMINKEKIG----------------------RPHRCFFTHYTTTYICIPAKTIEIC---------------EDERGLLRCG--------------------------------------------------------------------------------------------NGRIKVIAANYGRTDGT---------------------TCLRRPP---------------------------------------------FRRR------------------------------------------------------LNTNCYSQNTLDLVSQRCDGRRRCS-----LTATNDVFSDP--------CAGT------------------RKYLKITYYCQS----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ** * : **. :. .* . :.: * . *:.. . * . .*: : .. : .* ..* : * * * :* : * *: * :* .* : .:: ** : :* *:: .* * . : *:. **. ****. .. :* :: * **:..: **::.* **. :*. * .. :** : :.::: . * . :: : * *.* : : * .:* ", "identical_positions": 55, "similar_positions": 79, "identity": "8.84%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1928", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2V9-1", "uniprot_id": "TM39A_RAT", "id": "Q5U2V9-1", "name": "Transmembrane protein 39A", "aln": "MPSRRRGPSRQQLSRSALPSIQTLVGGGCGNGTGLRNRNGSAIGLPVPPTTALITPGPVRHCQIPDLPVDGSLFFEFLFFIYLLIVLFIQYINIYKTVWWYPYNHPASCTSLNFHLIDYYLAAFITVMLARRLVWALISEATKAGAASMVHYTALILARLVLLTLCGWVLCWTLVNLFRSHSVLNLLFLGYPFGVYVPLYCFHQDSRAHLLLTDY--VVQHQAVEDAASNVGSLTRSKDFLSLLLESLKEQFN-NSTPIPTHSCPLSPDLIRNEVECLKADFNHRIKDVLFNSLFSAYYVAFLPLCFVKSTQYYDMRWSCEHLIMVWINAFVMLTTQLLPSKYCDLLHKSAAHLGKWQKLE-----HGFYSNAPQHIWSENTIWPQGVLVRHSRCLYRAMGPYNVAVPSDGSHARFYFLFHRPLRVLNLLILIEGSVIIYQLYSLLRS-EKWNHTLSMALVLFCNYYVLFKLLRDRIVLGRAYSYPSTATDSRQTKLPLSSEGELR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CYC3-1", "uniprot_id": "TM39A_MOUSE", "id": "Q9CYC3-1", "name": "Transmembrane protein 39A", "aln": "MPSRRRGPSRQQLSRSALPSIQTLVGGGCGNGTGLRNRNGNAIGLPVPPTTALITPGPVRHCQIPDLPVDGSLFFEFLFFIYLLIVLFIQYINIYKTVWWYPYNHPASCTSLNFHLIDYYLAAFITVMLARRLVWALISEATKAGAASTVHYTALILARLVLLTLCGWVLCWTLVNLFRSHSVLNLLFLGYPFGVYVPLYCFHQDSRAHLLLTDY--VVQHQAVEEAASNVGSLARSKDFLSLLLESLKEQFN-NATPIPTHSCPLSPDLIRNEVECLKADFNHRIKEVLFNSLFSAYYVAFLPLCFVKSTQYYDMRWSCEHLIMVWINAFVMLTTQLLPSKYCDLLHKSAAHLGKWQKLE-----HGFYSNAPQHIWSENTIWPQGVLVRHSRCLYRAMGPYNVAVPSDVSHARFYFLFHRPLRVLNLLILIEGSVVFYQLYSLLRS-EKWNHTLSMALILFCNYYVLFKLLRDRIVLGRAYSYPLNSYELKAN-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NV64-1", "uniprot_id": "TM39A_HUMAN", "id": "Q9NV64-1", "name": "Transmembrane protein 39A", "aln": "MPGGRRGPSRQQLSRSALPSLQTLVGGGCGNGTGLRNRNGSAIGLPVPPITALITPGPVRHCQIPDLPVDGSLLFEFLFFIYLLVALFIQYINIYKTVWWYPYNHPASCTSLNFHLIDYHLAAFITVMLARRLVWALISEATKAGAASMIHYMVLISARLVLLTLCGWVLCWTLVNLFRSHSVLNLLFLGYPFGVYVPLCCFHQDSRAHLLLTDYNYVVQHEAVEESASTVGGLAKSKDFLSLLLESLKEQFN-NATPIPTHSCPLSPDLIRNEVECLKADFNHRIKEVLFNSLFSAYYVAFLPLCFVKSTQYYDMRWSCEHLIMVWINAFVMLTTQLLPSKYCDLLHKSAAHLGKWQKLE-----HGSYSNAPQHIWSENTIWPQGVLVRHSRCLYRAMGPYNVAVPSDVSHARFYFLFHRPLRLLNLLILIEGSVVFYQLYSLLRS-EKWNHTLSMALILFCNYYVLFKLLRDRIVLGRAYSYPLNSYELKAN-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PH58-1", "uniprot_id": "TM39A_DANRE", "id": "Q6PH58-1", "name": "Transmembrane protein 39A", "aln": "MPGGRRGPSRQQLSRSALPSLQTLVGGGLSNGAGLRCRSSSAVGLSAPPLTALITPEPVRHSRIPDLPLDSNLLFETLLLLYLLVALLVQYINIYRTVWWSSYSQPTASTSLNFHLMDAHLAVFIAVMLSRRLVWTLLSEVCVACPASPLCYVLLLVVRVCVLTLCGWVLCWTLLNLFRSHSVLKLLFLGYPFGVYVPLCCLHQDGSP----------AADCGFADADGADGALLQPRDFLTLLRENLRQQLSGTHTHTHTHTCPPSPELIRSEVQQLKTDFNRRIKEVLFNSLLSAYYVAFLPLCFVKSTQYYDMRWSCEHLIMVWINAFVMLMSHLLPPHYCDLLHRCAAHLGRWQRLE-----PGSCSNTPQHTWSDSTIWPQGVLVRHSRCLYKAVGPYNVALPSDVSHARFYFLFHKPLRLLNVLIGIECSVVVYQLYSLLRS-ERWNHTLSLGLILVCNYYVLFKLLRDRLVLGKAYSHPLGSAGLGMKRD---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9L5-1", "uniprot_id": "A1Z9L5_DROME", "id": "A1Z9L5-1", "name": "Transmembrane protein 39A", "aln": "MTYDERSSDGSSSSETHDSFAHLLATK---------------QGQSQTPATAMP-----KHIPFPEHATTSEWLSELIMCAFTMGSAIVQFINIYRTNWWLPQAHTR--HMVNIELIDPYLRYLLLILNTRRLIYCLLLVKIRK-RNEKSRHLIRLGIKYGFGGLVQLSLGFCAMKLYQKHTYILLLFLFYPVVIYLLIFGFQ---------------------------------LEPFLRTRFELPGVYIN----DLPVHSCTTNPVNIRDEVETLRHDFNKRFKQLIFTSMLNAYYTGLVPCCLAVSVQYNVLR-AAQHCIIVCLGAFSLCAVFLYPAKYSDTLHRATLHLGCWQRIDREPAPSQLIVAASALTWSKYSSYNHGTVVKHNGGLYRSHGMVTVATPGNASHARFYKLFHNPTIIYSTLAILQAAVLLVEIGSLSAESVEWHFVLSISFVAFTSMGAFFKLVRDYLITKDLYKAEHAVAPDQPFRQRMRDAFM--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. .*... .. *.: . : *. * . .* **: :* :*: . .. : * :: : : ::*:****:* ** . :. :*:.*:* :* :: :: :***:: *: . : : : . * * : ::*::.*: : **** **. :*: : :: . ** * :. .*:*. .* **.**: *: ***:*:*:::*.*::.***..::* *:. *.** :* :.:* *:* :.** : * *.:*.* **:.: *** **::: :. **. : : :*.:*:*. **:: * .** *.: ****** ***.* : . * :: :*:. :: ** . .*:..**:.:: . . .:***:** :: *. ", "identical_positions": 115, "similar_positions": 150, "identity": "22.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1946", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54927-1", "uniprot_id": "WSB1_MOUSE", "id": "O54927-1", "name": "WD repeat and SOCS box-containing protein 1", "aln": "MASFPPRVNEKEIVRSRTIGELLAPAAPFDKKCGGENWTVAFAPDGSYFAWSQGYRIVKLVPWSQCRKNFLLHGSKNVTNSSCLKLARQNSNGGQK-NKPPEHVIDCGDIVWSLAFGSSVPEKQSRCVNIEWHRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHIEMVRDLTFAPDGSLLLVSASRDKTLRVWDLKDDGNMVKVLRAHQNWVYSCAFSPDCSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYVWDPHNGDLLMEFGHLFPSPTPIFAGGANDRWVRAVSFSHDGLHVASLADDKMVRFWRIDEDCPVQVAPLSNGLCCAFSTDGSVLAAGTHDGSVYFWATPRQVPSLQHICRMSIRRVMSTQEVQKLPVPSKILAFLSYRG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6I7-1", "uniprot_id": "WSB1_HUMAN", "id": "Q9Y6I7-1", "name": "WD repeat and SOCS box-containing protein 1", "aln": "MASFPPRVNEKEIVRLRTIGELLAPAAPFDKKCGRENWTVAFAPDGSYFAWSQGHRTVKLVPWSQCLQNFLLHGTKNVTNSSSLRLPRQNSDGGQK-NKPREHIIDCGDIVWSLAFGSSVPEKQSRCVNIEWHRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLCCAFSTDGSVLAAGTHDGSVYFWATPRQVPSLQHLCRMSIRRVMPTQEVQELPIPSKLLEFLSYRI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T2F6-1", "uniprot_id": "WSB1_DANRE", "id": "Q7T2F6-1", "name": "WD repeat and SOCS box-containing protein 1", "aln": "MASFPDCVNENEIGKAKFIGELIPPVAPFDQKSGRETWTVAFAPDGSYFAWSQGHRIVRLVPWKKCLASFSVRKEDRSSGAGPRRLSRQNSEGSLLPGEPREHTIDCGDIVWGLAFGSSVPEKQSRCVNIEWHRFKFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLMDHTDIVRDLTFAPDGSLVLVSASRDKTLRVWDLKDDGNMVKVLRGHQNWVYCSAFSPDSSVLCSVGAGKAVFLWDMDKYTLIRKLEGHHNDVVCCEFSPDGALLATASYDTRVIVWDPHTATVLLELGHLFPPPSPIFAGGANDRWVRSVAFCHDGRHIASVTDDRLVRFWSIDEKSPQAIGPLTNGLCCAFSTDGSVLSAGSRDGSVHFWASPRSIASLQHLCRMTLRRVMPTQQVYTLPIPFSMQDYLAYKTL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** ***:** : : ****:.*.****:*.* *.*****************:* *:****.:* .* :: .. :.:. :*.****:*. .:* ** ********.**********************:*******************************:** ::************:*********************:****.******..*****.*:******.******:*****:********:***.*:***************** :****.. :*:*:*****.*:*************:*:*.*** *:**::**::**** ***. * :.**:**************:**::****:***:**.:.****:***::****.**:* **:* .: :*:*: ", "identical_positions": 303, "similar_positions": 85, "identity": "71.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1957", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R3J5-1", "uniprot_id": "CHAC1_MOUSE", "id": "Q8R3J5-1", "name": "Glutathione-specific gamma-glutamylcyclotransferase 1", "aln": "------MKQESASQSTPPPSLSPAPSSAQPSWGDGDPQ-----------------ALWIFGYGSLVWKPDFAYSDSRVGFVRGYSRRFWQGDTFHRGSDKMPGRVVTLLE-------------------------DREGCTWGVAYQVRGEQVNEALKYLNVREAVLGGYDTKEVTFYP----------------QDTPDQ--PLTALAYVATPQNPGYLGPAPEEVIATQILACRGFSGHNLEYLLRLADFMQLCGPQAQDEHLEAIVDAVGTLLPCSYLPEQPLALT-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B3STU3-1", "uniprot_id": "CHAC1_RAT", "id": "B3STU3-1", "name": "Glutathione-specific gamma-glutamylcyclotransferase 1", "aln": "------MKQESAAQSTPPPSLSPAP-SAQPSWEDGDPQ-----------------ALWIFGYGSLVWKPDFAYSDSRVGFVRGYSRRFWQGDTFHRGSDKMPGRVVTLLE-------------------------DHEGCTWGVAYQVRGEQVSEALKYLNVREAVLGGYDTKEVTFYP----------------QDTPDQ--PLTALAYVATPQNPGYLGPAPEEVIATQILACRGFSGHNLEYLLRLADFMQLCGPQAQDEHLEAIVDAVGSLLPCSYLSEQPLALI-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BUX1-1", "uniprot_id": "CHAC1_HUMAN", "id": "Q9BUX1-1", "name": "Glutathione-specific gamma-glutamylcyclotransferase 1", "aln": "------MKQESAAPNTPPTSQSPTP-SAQFPRNDGDPQ-----------------ALWIFGYGSLVWRPDFAYSDSRVGFVRGYSRRFWQGDTFHRGSDKMPGRVVTLLE-------------------------DHEGCTWGVAYQVQGEQVSKALKYLNVREAVLGGYDTKEVTFYP----------------QDAPDQ--PLKALAYVATPQNPGYLGPAPEEAIATQILACRGFSGHNLEYLLRLADFMQLCGPQAQDEHLAAIVDAVGTMLPCFCPTEQALALV-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SPB6-1", "uniprot_id": "CHAC1_DANRE", "id": "Q5SPB6-1", "name": "Glutathione-specific gamma-glutamylcyclotransferase 1", "aln": "------MKPQDIVAGKS--------------------------------------SLWIFGYGSLVWKPDFKYKRSKVGYIKGYKRRFWHGDNFHRGDDEMPGRVVTLIE-------------------------EDDVCTWGVAFEVTGSQMEESLKYLNVREAVRGGYLTRAVDFFP----------------RGTNQP--PVQALVYIATPDNPIYLGPASTEEIASQIAVCKGNSGHNIEYLLRLAEFMRVSCPDVDDPHLFSIEAALLATIRPILLAA-----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCI9-1", "uniprot_id": "Q9VCI9_DROME", "id": "Q9VCI9-1", "name": "glutathione-specific gamma-glutamylcyclotransferase", "aln": "MAHFSGHRQPATVPSHFKDLFTNGQLGAAEESNNNDQNEQENRPSNNNNAGPSDPACWVFGYGSLCWHPGFNYTKCITGYIRGYVRRFWQGNVTHRGCEEKPGRVATLVE-------------------------DKEGITWGCAYRITG---STALDYLKQRECTLGGYATIDTKFFPR------------VASQDTPFSGEAVEVLVYVATPENIYWLGDDPVEEIAQQIVSCRGPSGHNAEYLLRLALFMHEEIPGVRDDHLFELEQLVLEELYRRQIPLSSVMGRNPDRIRRDSHEDIRRPPSFEFTSRVPDTKLRCLNI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32656-1", "uniprot_id": "CHAC_YEAST", "id": "P32656-1", "name": "Glutathione-specific gamma-glutamylcyclotransferase", "aln": "------MTNDNS-------------------------------------------GIWVLGYGSLIYKPPSHYTHRIPAIIHGFARRFWQSSTDHRGTPANPGRVATLIPYEDIIRQTAFLKNVNLYSESAPIQDPDDLVTIGVVYYIPPEHAQEVREYLNVREQNGYTLHEVEVHLETNREHEAELGEALEQLPRHNKSGKRVLLTSVYIGTIDNEAFVGPETVDETAKVIAVSHGPSGSNYEYLAKLEQALAQMPIMKERGRITDHYLTALLETVNKYR-------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *::***** ::* *. . ::*: ****:.. *** ****.**: : * * .: : . .**: ** . : . : : . .*:.* :* ::* . : * * .:* ** * *** :* : :: ", "identical_positions": 42, "similar_positions": 42, "identity": "12.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1961", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C1G7-1", "uniprot_id": "WBP1L_RAT", "id": "P0C1G7-1", "name": "WW domain binding protein 1-like", "aln": "--------------------------MPFLWG---------------LRQDKEACVGTNNQSYICDTGHCCGQAQCCSHYYELWWFWLVWTIIIILSCCCVCHHRRAKHRLQAQQRQHEINLIAYREAHNYSALPFYFRFLPNYLLPPYEEVVNRPPTPPPPYSAFQLQQQQ-LLPP--QGGPAGGSPPGADQP-QGSQGAQSSPLSGPSRSSTRPPSVADPQSLEVPTERAATKALGMESSSSVASHGELDPGAFLDRDSECKEELLKDSSSEHGGAPPDSKDKTPGRHRRFTGDSGIEVCVCNRG----HHDDDLKEFNTLIDDALDGPLDFCDSCHVRPPVDEEEGLCLSSEGQAREHGHPHLPRPPACLLLNTINEQDSPNSQRSSSPS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGW2-1", "uniprot_id": "WBP1L_MOUSE", "id": "Q8BGW2-1", "name": "WW domain binding protein 1-like", "aln": "--------------------------MPFLWG---------------LRQDKEACVGTNNQSYICDTGHCCGQSQCCNYYYELWWFWLVWTVVIILSCCCVCHHRRAKHRLQAQQRQHEINLIAYREAHNYSALPFYFRFLPNSLLPPYEEVVNRPPTPPPPYSAFQLQQQQQLLPPPPQGGPPGGSPPGADPPPQGSQGAQSSPLSGPSRSSTRPPSVADPQSPEVPTDREATKASGTESGSPMAGHGELDPGAFLDQDSECKEELLKDSRSERGGVSPDSEDKTPGRHRRFTGDSGIEVCVCNRG----HHDDDLKEFNTLIDDALDGPLDFCDSCHVRPPVDEEEGLCLSSEGQAREHGHPHLPRPPACLLLNTINEQDSPNSQHSGSPS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NX94-1", "uniprot_id": "WBP1L_HUMAN", "id": "Q9NX94-1", "name": "WW domain binding protein 1-like", "aln": "--------------------------MPFLLG---------------LRQDKEACVGTNNQSYICDTGHCCGQSQCCNYYYELWWFWLVWTIIIILSCCCVCHHRRAKHRLQAQQRQHEINLIAYREAHNYSALPFYFRFLPNYLLPPYEEVVNRPPTPPPPYSAFQLQQQQ-LLPP--QCGPAGGSPPGIDPT-RGSQGAQSSPLSEPSRSSTRPPSIADPDPSDLPVDRAATKAPGMEPSGSVAGLGELDPGAFLDKDAECREELLKDDSSEHG--APDSKEKTPGRHRRFTGDSGIEVCVCNRG----HHDDDLKEFNTLIDDALDGPLDFCDSCHVRPPGDEEEGLCQSSEEQAREPGHPHLPRPPACLLLNTINEQDSPNSQSSSSPS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N9F1-1", "uniprot_id": "A0A8M1N9F1_DANRE", "id": "A0A8M1N9F1-1", "name": "", "aln": "MSYRVANVPKATGKDGMWGVGFIKLGMGLFVSSAVIGPVGSVSVEAALTEGRLICVGVNNQSYYCDSGYCCDESQCCSYYYEVWWFWLVLTLIVILGCCCVCHHRRAKHRLQQQQRQHEINLIAYREAHNYSSLPFYFRFLPGYLLPAYEEVENRPPTPPPPYSASQP------------GHSTSSDPLCSEQPDELCPPLQSSPVT-PSASENHSPEPCTEQP-QTPTTHHPAKPQYLS----LEEDGRLQQVACATSHSLLKQDSSGEDLSQPGDCSPDSKDKTPGRHRRFTGDSGIEVCVCNQGPGDGEEEEEMKELVGHMDARGLEEQDFCDSCNPRSS-SPPRGPGDVEQGLADSDVPLEPQRPPVCLQLHTISEQDGPNHTSNTDPPS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: . * :.: ***.***** **:*:**.::***.:***:****** *:::**.*************** *******************:*********. ***.**** ************ * .....* : . . . ****:: ** *..:.*. . :. : *. : .:*. . : *.*: * .: ::: :. *: * .***::*********************:* ..::::**: :* ******: *.. . .* .: * . . ***.** *:**.***.** . .*. ", "identical_positions": 160, "similar_positions": 87, "identity": "40.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1966", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A853-1", "uniprot_id": "D4A853_RAT", "id": "D4A853-1", "name": "Protein capicua homolog", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYSAHRPLIPASG-------AASR-----------------------------------GLGMFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHP-VASNQSKEPAESAAVAHEQPPGGTGGADPGRPPGATCPESPGPGPPLTLGGVDPGKSLPPTTEEEAPGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEK--DGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPASLGLAGGHKETRERSMSETGTAAAPGVSSELLSAAAQTLLSSDTKAPGSGPCGAERLHAVGGPGSARPRAFSHSGVHSLDGGE-VDSQALQELTQMVSGPTSFSGPKPSPQYGAPGSFAAPGEGGNLATSGRPPLLPSRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDSFGTTDIDLKCKERVTDSESGDSSGEDPEGNKGFGRKVFSPVIRSSFTHCRPTLDPEPPGPPDPPAAFSKGYGPTPSS-SSSPASTSVSVSTSFSLGSGTFKTQESGQGSTAVPLRPPPPGAGGPTTPSKATRFLPTDSATFRRKRPESVGSLEAPGSSVIAAPPSGGGNILQTLVLPPSKEDREG--TRVPSAPAPSLAYGAPAAPLCRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASSNDTVGARTEMGTGSRVPGGSPLGVSLVYSDKK-SAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPASPAVQFIAQGAPGSATPAGSGASAGSGPNGPVPLGILQPGALGKAGG---ITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTAGIPILQSVPSAPPPKAQSVSPVQATPSGGSAQLLPGKVLVPLAAPSMSVRGGGAGQP-LPLVSSPFSVPVQNGAQQPSKIIQLTPVPVST----PSGLVPP-------LSPATMPGPTSQP-QKVLLP-SSTRITYVQSAGG--HTLPLGTSSACSQTGTVTSYG---PASSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACTAPGGPVITAFYPGSPAPTS-APLGPPSQAPPSLVYTVATSTTPPAAAILPKGPPASATATP--APTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFESGTTGRTGPTPRQSLDSGVAREPAAPESELEGQPTPPAPPPPTETWPPTARSSPPPPLPAEERPGTKGPE-TASKFPSSSSDWRVPGLGLESRGEPPTPPSPAPAPATGPSGSSSGSSEGSSGRAAGDTPERKEVTSSG-----------------------KKMKVRPPPLKKTFDSVDN--------RVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKS-AKCEGDIFTFDRTGTETEDVLGELEYEKVPYS--SLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEASLPGPPPTGMAATPVPTPSPAGGPDPTSPGSDSGTAQVAPPLPPPPEPGPGQPGWEGAPQPSPPPSGPSTAATGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q924A2-4", "uniprot_id": "CIC_MOUSE", "id": "Q924A2-4", "name": "Protein capicua homolog", "aln": "MKPMKKACPG--LAGSASGSK---------SPPATRAKALRRRGAGEGDKPEEE--EEAQPQEQAGPEEAEEGEEEEAERDPGAEGT----------------------------------------------------HPELQPNDPTPGLTEDPKGDGEAGRWEPSLSR----------KTATFKSRAPKKKYVEEHGTGNVGVVG---------------------------------------------------------------------------APEERERTPEDASALGVPPRPPTSTRSSSTDTASEHSADLEDEPPEACGPGPWPSTGTSEGYD------------------------------LRQLRSQRVLARRG-------------DGLFLPAVVR-QVRRSQDLGVQFPGDRALTFY-----EGVPGGGVDVVLDVTPPPGALMVGTAVCTCVEPG----VAAYREGVVVEVATKPAAYKVRLSPGPSSHAGPPGTLPQAQQTLHREPEEAVWVTRSSLRLLRPPWEPGALLRKHPAGPEEEQAEPGPALPPCPSSVEPKQP----------------------------------EDAEVSNISFGSNLGTRCEEGEEKHPP------------------------------SLGTPVLLPLPPPQLLSPPPKSPAFGGPGR---------PSEQPSPCQEGSQGG-------------SRSSSVASLEKG----------------AAPAARARTPLTAAQQKYKKGDVVCTPNGIRKKFNGKQWRRLCSRDGCMKESQRRGYCSRHLSMRTKEMEG-LADSGPGGTGRPAGVAAR------EGSTEFDWGDETSRDSEASSVAARGDSRPRL----VAPADLSRFEFDECEAAVMLVSLGSSRSGTPSFSPVSTQSPFSPAPSPSPSPLFGFRPANFSPINASPVIQRTAVRSRHLSASTPKAGVLTPPDLGPHPPPPAPRERHSSGILPTFQTNLTFTVPISPGRRKTELLPHPG----TLGASGAGGGGAAPDFPKSDSLDS----------GVDSVSHTPTPSTPAGFRAVSPAVPFSRSRQPSPLLLLPPPAGLTSDPGPSVRRVPAVQRDSPVIVRNPDVPLPSKFPG-----EVGTAGEARAGGPGRSCRETPVPPGVASGKPGLPPPLPAPVPITVPPAAPTAVAQPMPTLG-------LASSPFQPVAFHPSPAALLPVLVPSSYPSHPAPKKEVIMGRPGTVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHP-VASNQSKEPAESAAVAHEQPPGGTGGADPGRPPGAVCPESPGPGPPLTLGGVDPGKSLPPTTEEEAPGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEK--DGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPASLGLAGGHKETRERSMSETGTAAAPGVSSELLSVAAQTLLSSDTKVPGSGPCGAERLHAVGAPGSARPRAFSHSGVHSLDGGE-VDSQALQELTQMVSGPASYSGPKPSPQYGAPGSFAAPGEGGTLATSGRPPLLPSRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDSFGTTDIDLKCKERVTDSESGDSSGEDPEGNKGFGRKVFSPVIRSSFTHCRPTLDPEPPGPPDPPAAFSKGYGPTPSS-SSSPASTSVSVSTSFSLGSGTFKTQESGQGSTAVPLRPPPPGAGGPATPSKATRFPPTDSATFRRKRPESVGSLEAPGPSVIAAPPSGGGNLLQTLVLPPSKEDREG--TRVPSAPAPPLAYGAPAAPLCRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASSNDIAGARTEMGTGSRVPGGSPMGVSLVYSDKKSAAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPASPAVQFIAQGAPGSATPAGSGASTGSGPNGPVPLGILQPGALGKAGG---ITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTAGIPILQSVPSAPPPKAQSVSPVQATPSGGSAQLLPGKVLVPLAAPSMSVRGGGAGQP-LPLVSSPFSVPVQNGAQQPSKIIQLTPVPVST----PSGLVPP-------LSPATMPGPTSQP-QKVLLP-SSTRITYVQSAGG--HTLPLGTSSACSQTGTVTSYG---PTSSVALGFTSLGPSGPAFVQPLLSG-QAPLLAPGQVGVSPVPSPQLPPACTASGGPVITAFYPGSPAPTS-APLGPPSQAPPSLVYTVATSTTPPAATILPKGPPASATATP--APTSPFPSATG-SMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFESGTTGRPGSTPRQSSDSGVAREPAAPESELEGQPTPPAPPPPTETWPPTARSSPPPPLPAEERPGTKGPE-TASKFPSSSSDWRVPGLGLESRGEPPTPPS--PAPATGPSGSSSGSSEGSSGRAAGDTPERKEVTSSG-----------------------KKMKVRPPPLKKTFDSVD---------KVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKS-AKCEGDIFTFDRTGTETEDVLGELEYEKVPYS--SLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPGPPPTGMAATPVPTPSPAGGPDPTSPGSDSGTAQVAPPLPPPPEPGPGQPGWEGAPQPSPPPSGPSTAATGR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RK0-1", "uniprot_id": "CIC_HUMAN", "id": "Q96RK0-1", "name": "Protein capicua homolog", "aln": "MKPMKKACTG--LSGPGSGSK---------SPPATRAKALRRRGAGEGDKPEEEDDEAQQPQPQSGPEEAEEGEEEEAERGPGAEGP----------------------------------------------------PLELHPGDPAPGPAEDPKGDGEAGRWEPSLSR----------KTATFKSRAPKKKYVEEHGAGSSGVAG---------------------------------------------------------------------------APEERVRTPEEASGLGVPPRPPTSTRSSSTDTASEHSADLEDEPAEACGPGPWPPGSTSGSYD------------------------------LRQLRSQRVLARRG-------------DGLFLPAVVR-QVRRSQDLGVQFPGDRALTFY-----EGVPGAGVDVVLDATPPPGALVVGTAVCTCVEPG----VAAYREGVVVEVATKPAAYKVRLSPGPSSQPGLPGSLPQPPQPLHREPEEAVWVARSSLRLLRPPWEPETMLRKPPTGPEEEQAEPGATLPPCPAALDPKQP----------------------------------EDAEVSKISFGGNLGTHCEEGEEKHPP------------------------------ALGTPALLPLPPPQLLSPPPKSPAFVGPGR---------PGEQPSPCQEGSQGG-------------SRSSSVASLEKG----------------TAPAARARTPLTAAQQKYKKGDVVCTPSGIRKKFNGKQWRRLCSRDGCMKESQRRGYCSRHLSMRTKEMEG-LADSGPGGAGRPAAVAAR------EGSTEFDWGDETSRDSEASSVAARGDSRPRL----VAPADLSRFEFDECEAAVMLVSLGSSRSGTPSFSPVSTQSPFSPAPSPSPSPLFGFRPANFSPINASPVIQRTAVRSRHLSASTPKAGVLTPPDLGPHPPPPAPRERHSSGILPTFQTNLTFTVPISPGRRKTELLPHPG----ALGAPGAGGGGAAPDFPKSDSLDS----------GVDSVSHTPTPSTPAGFRAVSPAVPFSRSRQPSPLLLLPPPAGLTSDPGPSVRRVPAVQRDSPVIVRNPDVPLPSKFPG-----EVGTAGEVRAGGPGRGCRETPVPPGVASGKPGLPPPLPAPVPITVPPAAPTAVAQPMPAFG-------LASSPFQPVAFHPSPAALLPVLVPSSYTSHPAPKKEVIMGRPGTVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHP-VASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEK--DGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKETRERSMSETGTAAAPGVSSELLSVAAQTLLSSDTKAPGSSSCGAERLHTVGGPGSARPRAFSHSGVHSLDGGE-VDSQALQELTQMVSGPASYSGPKPSTQYGAPGPFAAPGEGGALAATGRPPLLPTRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSSGEDPEGNKGFGRKVFSPVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKK-SAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGG---ITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQP-LPLVSPPFSVPVQNGAQPPSKIIQLTPVPVST----PSGLVPP-------LSPATLPGPTSQP-QKVLLP-SSTRITYVQSAGG--HALPLGTSPASSQAGTVTSYG---PTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATP--APTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSS----ESSSGRAAGDTPERKEAAGTG-----------------------KKVKVRPPPLKKTFDSVDN--------RVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKS-AKCEGDIFTFDRTGTEAEDVLGELEYDKVPYS--SLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGPSTAATGR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BKS3-1", "uniprot_id": "A0A8M2BKS3_DANRE", "id": "A0A8M2BKS3-1", "name": "Protein capicua homolog", "aln": "MRPPKKQRGRSPLSARGKGTRKRGGKLDGHSQTTLPAPSHQKYTPSKEDNSLDKQIKSSNMTNSEGLKEQIKERTMETSKSEENAGVGNKAKSPKNINTNNLTDNTDSIKIASNAHENSHSNSTDICNTNTQNLTSTNSKSSNQHTNSTASNTQNTNNIGNSLNKSSSLSANHTSTTLSSRKTATFKARVPKKKYMYEHQATSTSPISSKPVTQLTLHINHLGSPQNSISQNTTPVIRNDLFKANTSDLDDSGNSRSRLEIANIASTETSKGDRIMGDMLKSEVPSEVEKVIQMGEADGYGEQAPNSVRSSSTDTASEHSVDLEVLEPSCMQLNSGNHVRASRRFNPLNNSTLSVVLSPNHTQVEQEGSATVAETLAKGLKNQRVLARRRPRRSLKEDEKLVKECIFICGVVRGSNKEQLNVELQINGEGTLLSYPFHTLVSRPHQPIDLILDA-PPPGNELVEVGTRVCVPYGGDKEKEWYREGVVAQVDSHSACPYMVLLQEEQKKE-------RCSKEETKQTSSSVWVARQNLRLLVPPWDGVMREKEREEREHREEIEVERELCQLSEGMDLVTAGPPRENCRFPSPDTGAHRYESTLSSSTSPAVVMVANNMFGLASRGENEGTENRERVREREHERKQLQTPEVDMEVLRLNMAPLRDSGGPLVSGGPKTGAPNQHRQILSKPPGYPSPITVVRGISGTTLGSPQPTPSSAVLGSDGGNSHHISPSVPPSPSSRGSLTPLEKTPTPSQTSTPVPGSSASSASSSRSRTPLSAVQQKYKKGDVVCTPNGIRKKFNGKQWRRLCSREGCMKESQRRGYCSRHLSMRTKEMEGAVGERGSGGGGESSSGTVTPSDLRGRASSEFEW-DETSRDSSETSSRG-TDSRPRLGLPSLLPQDFSRFDFDECEAATMLVSLGS-RSVTPSFSPISNQSPFSPTPSPSASPLFGFHPANFSPITASPVLP----HRRHKHPSGTNSGLPKHGTGG----TEREKDRHLSGIVPSFHPNLTFTVPMSPGKRRTDAPPPPVPLLQEYTKPDQEQSCRDPSLVTNLCIISPQTTTVTHPQRLLSTTASSSPASPLSLESGSQCTISQQPLRDSPVIVRNPEVPLIKFTELPLARVAEVDRTSFTENSQTGVHPETGLQVPVPINAASTNGSVLLQNPTSTLVLVSTTSSILNPNPAGLPTQPSATLACISVPSPVSGAGLIGAGDGGGQDKSCPVTLQQPVPCHPAPTALLPLILP-TETLHPVPCKDIIMGRPGTVWTNVEPRSVPVFPWHSLVPFLAPTQSDPSAQPGEGQQTVSHP-QTAALKKE-SQSGSVLKEIIEG---------APNPSSRPTP------------SADELPPEREKDAE----RERPDSETESDVDDPFFPSVLPDPPISASPGKRRSQSLSALPKD---------DKNSPGKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEGR----GVPGG-KDIRERSMSETTEPPSVSMGMELKGMGPGMVSVS------------ERVGGEGHGQLTRPRAFSQSAMHSLERSERGNPQALAELAQMCG------------------------DGSQVGGRG-------ALSQTQRGVSEDMTSDDERMVICEEEGDDDVIEDS-YPGSSIDLKCKERVTDSDSENGSGDEGER-----KRVFAPVICS--------------------SSYGPGHG-RSVSLSSYPTSRRFSDTSSKRK-----RTIEAGDGEQRE-------GEGGASQPS--------------------------AGQSILVS--SGGG---------------------VSSMLG-----------AVRVASTVVTNVVRPVVSTPVPIASKSPHDRKLAPPQTQLLIGHGATGNTAAASAGG--------------GGYYSSSSPSPINAPAG-----QAGLVTNLVLGG---TFQAPPAVQLVTP-PPPSQNPASPAHSNGPLPLPVLQSHILPSGSLAPSSGQKPITQVQYILPTLSANNPKSPSPQQAS----------QPTS--IFTLPTALPTHATLANGKQ--------SGYVSSPVGVVSPGARVQTQSP-----VLQGKMLVPMAT----VRAAPAPSPQFPLVAPP--LPVQNGAQAGSKIIQIAPMPVVQSQLPSAGPVQPGSPFSVTMGTATVVAPGSTPSQTVLLPPPPTRITYVQSTPGVPSPLPLVPSTTGSSSQTVSAAPGSAYVSSPLATFAAIAHPGQTLVQPLIAG-QPSLLAPAQS-PNPPHAPAITAIYTPTNVTLATGVVSMATVSPSVVYTVSSSSSLSPHILPKHTTATSMTPVTLDRQVNVSVHSERQLHQERSLERQHTDSQVYTLSSERQTEKGCLLQLDKHFQVPSKGSGSSVAPPSATSVPLQPGS-PAQPSHSGSAPGTPKLITARPPQKVKATLANIPVGSYDGGGRGKEREKDRDRDKEREREKDKDTSSRFSFEVEKVEKIEKSNSPAEEGAPETPTHSGVETSAPSGRCKETNAKEVEKKDSHPSSPLPPPSGSDPFPSQSHGDKDAPPKKVKARPPPLKRPFDSVDKLVKIFGWHRVLSEVYFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRRKRKNSTDLDSSTEDPISPKRKSRRRSSCSSEPNTPKSAAKCEGDIFTFDRP--DGEDILGELEFDKVPYS--SLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPTKVCLQLKIREVRQKIMQTAAPSESAGISDLSLPGP-------SGVVTLDPALGADPLEKEVEREGEQHSP----------EEPRNAGDSQDSSR-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9U1H0-1", "uniprot_id": "CIC_DROME", "id": "Q9U1H0-1", "name": "Putative transcription factor capicua", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNAFQDFELGAKLYLQCLLSLSSSRSATPSYTSPVNHAGASPLNAIAHSPVN--VSATHRQNFFTPIAN-----QSQQQQQQQPVAVPLDSKWKTTPSPVLYNANNNSSNNNTSSSNNNNNSNWEVGSNSNTHVAATAAATSTVGAQPLPPQTTPVSLVMHAPPPQQQ------PLQQQHHHHQPPPPPPASLPAPSAPPTSGSSSSHNSVGHATSVIRISSSQQQHQQQQQHQQQAHPHVVVSGGQTFHPVIVDATQLSVPLPPTTVSFHQPNTPTSTAASVASMSQDKMLAKNGYNAPWFKLLPHMTPMSKASPAPVTP--------------------------------------------------TLTTSASSYNVVMMQQQQQHQQLQQQQQLQQQQQSPPQMPLNHNNNHLIVSAPLSSPGKPLNCSMNDAKVAAAAAAAAVANQRQKQQQEEPDDQLDDDVFETTTPGISANSKKQTAAMRLPTHNSNIRKLEECHDDGAAGAPATSAAKRRSQSLSALQQQQQQQQQAGAAGTAAGQPANKKIRRPMNAFMIFSKKHRKMVHKKHPNQDNRTVSKILGEWWYALKPEQKAQYHELASSVKDAHFKLHPEWKWCSKDRRKSSTSTATPG-GKASGAAGTGDAKQRLVSVDGSDSLEHDMCPSTPGGSGSCGGQGISSDLQGDIIPLTIDNYNSTCDEAPTTISMKGNGNGKLMKNELPSDEDEQMLVVEEEQQQQ-------------TVKKIDLHCRERVNDSDMDDTPFDYRKQQPEANQRSAEEHSTSGANGQAINAPPLSGGEREITLKPKAIKAHPVLESNMLPYTQMSIYTQYTSPKNPIGVTPFQPTGGAFKSMPISPKGSGGKPEDAGSLQAHIKQEDIKQEPPSPYKLNNGSGSASGGGVVSAPPPNSGSVGAIFNFNVPTATALSQKQFHYPMHHPHRSPTDLRDEEADREEITQGTKSGESSEKDKPALDDQERDEVEEEDEDEEDDDEDDEDDEQFMQELASVNASAGFDDLVPYAMPKVVITPTPTPPPVATIVTPIKRKQFTIVRSLTPLQ------------------PSNSPHQQLKHLHQRRGETPPTVITRVPTPTINHFTIIRTQQHPHTHPHNTPPPLFFKQKVQGSP----VIATVTTSTLSSSSS----NPANNEAPNKFSNFPTQHQPTTTTTISCNTNNNATPIIRKLLTLQEGAELGGSHKGTGR--AAILYDALVLDTLHGQDEEEEEDEGNAEKQENPKVAGKEQVTTSQPATMLLITDVNAYNQQHVAGNAATPVS-GAATLRPVSFISINACNKITLPANARILT---------AATATSTAAGAAVTSQAGATLTVMTKASAATNHSSSNASDITITAASAAPVPTSGSSIVMINSTTNPSTSSNSTSCSAAAHQACVPSSPAGMGLGHAANIATPPASAPAQIMGGGPASQKMFFAMTHPYTLLQRSHQPGTPSLEHLQLDAFAPGGYTLRNHNGLSSLPPPVSAQPTMLLHGYPPSHGVEPPARSPSYKSMPSTPKSATYLMSAPPERGMDGGMSGCASAAASGGDESDIDADGQQ--FILAPTPAQLGRAPLQRRKNLSQSKSESNVSFGANLGASNGQHISRKLHSPTMMESSSPIIGHVNSSNLSSALPTPTSSTTTPNSDEQLPLTPTTSSSNSNLNQQQPKSPMKG-----------------------APGSTAAALKKKNDEMNN--------SVLKQVDFEKKYKALPQFQPEDCQ-SPSAIAVPSSPRVYGTNYRKKNTAPPPVQKLMCEDDSIDEPASAPPTTTQRFFGPDFNNELK-ELESSDQTGRSPRTPKTPLQSARSDASEKGHRKVLETRRSLVLQLFAEHGNFPTAQATMAFQSKHSDVFPRKQDLQLKIREVRQKLLGQASCTPHSAGPNTPSDSN-------SSSTTLSASSTSLNMQTTSAADVFQYY------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : *.... .* :: :. * * . * . * . .* . :... : . .. . . . .* . :: * :.... . . . ...***:****** :: :..: :.:*************:** :**::******************** *::* :**:** .**:**** **:****.***:***:. * ..* : . . : .: :: . . . : .* : .::. .: . : : : . : : : .: :.: . . . .:.:.* . ::. * :. .:.. *. : :* : . . . . . . .:. : .* . . . *: . : : .* . . *:. .: . : . .:* . . . . . : . .* :* . * . : : * . . * : ..:*. :.. . .: *. : * :. * :** . .. .: . : . : ** *. : : . *: **. ** : :: . . . : . .** .. : . . . * :* ..:: . . . : : :.: .*.: . :: . . . . : .. . . :* .. . : : . . . . .. : :. . : . . : . . . . :.: . . :. . . . . . . : .. . . : . : :. .. : .. . : .. ::: ...**: *.:: **.:* **::: **:*:**: **: ::.:***. .**:*.. .. ::. : * .. .: :.. *. : : :: : *:. . . *: : * . *:.*: **:**:*** :** **:**** ***::::*:** * ***********:: *: : . .: . : * ..: . . * ", "identical_positions": 180, "similar_positions": 380, "identity": "6.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1968", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZLZ9-1", "uniprot_id": "D3ZLZ9_RAT", "id": "D3ZLZ9-1", "name": "", "aln": "MTTLQTSKDPHLRGVSPNPSKIPVLSQRCSDFSSAKSGSLDQENQDPRRSAKKPLHRTQR--PLTDTAGLRSKALHQTEKSQRLRIT-QPRNPLEELKPSSGGSNVG-LTHPQTEASGAIEFVADPAALATILSGEGVKSCPLESRSSLAQRVLVRERKGGTH-IQRGQSARSSAYLAPRIRAHQADPARASCFSRLEGPG-----LRDRTFSSQRSEALNPRAGSSFHSSARPSLQELRRETCGGSRDGSCTDSRTSASQASRLLLKTPVQPASLTLRGDHEAVP--HSGGEGG-PKLGLAQRVPLKES--LTHTR-------------------------------------------TTYSSMKRFTTRRKTQFTPLRSLPRVQQAQWLSGLSPHSSPEEPALPWEQIAVKLFDQESLIALQKGPGKPSVASTSGPQSTRTPS---HQELKMQRIHILQQLLRQEVEGLATGNCAALNGGSALDTTERQPPVAEDSSTLSAPAHKSET-PLA-LPEHSGVTEALPAEEREEPQACPGEDTKESQPCSTTELKPPVP-----------------------HRAEPEPP--------------------------------------------APCLPALAGPPLPSCRGQAEPPEARPGIQLGASAASALQAGNPESSPEPCCSQGPPAATSLT-STQSPVCASFPIHSLHSSRSPTGRSGPSSVAPRTLALRQRLRACLTTIHCFHEARLDDECAFYTSRALPPGPTRVCTNPVATMLEWQDALRFIPVGPVAPQDSPS---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B7ZNG4-1", "uniprot_id": "TROAP_MOUSE", "id": "B7ZNG4-1", "name": "Tastin", "aln": "MTTLQTNKDPHLRGVSPNPSKIPVLSQRCQDFSSVKSRSLDQENQDPRTPAQKPPRSTQRQRPLTDTAGLRSKTLHQTEKSPSLKT---LRNPLEELKPSSGGSNVGLVTHPQTEAIGAIEFVADPAALATILSGEGVKSCPQGYRSSLAQRVLVRERKGGT--TQRGQSARSSAYLAPRIPTHQVGPARASCFSRLEGPG-----LRDHTLSPPRLEALNPPPGSS-HSSTRPSLQELRRETCGGGRDGDCTDRRTSASQASRLLLKTPVQPASLPLRGEQEAVP--HSDDGGGRHHLGLAQRIPLKES--LTNTR-------------------------------------------STYSSMKRFAIRRKAQFTPLRSLPKVQQAQWLSGLSPHSSPEEPALPWRQIAMKLFDQESRITLQKEPRKPSVASTSGPRPKRTPS---HQELRIQRINILQQLLQQEVEGLAMGDGAPLNGGSAFDMTELKLPTAEISRTLTASEHNSGA-ALVGLSQHSGATEPLLSEECEEPQAYP-EETKAAQPCSTTELKPPVP-----------------------HRAEPELP--------------------------------------------EPCLPALSGPPLPSCRGQAEPPMACPRTEPGASAACALEAGTPESSTQPCCNQGPPATASLTFSSQSPVCASPSIHSLY----PTGYSGPSSLAPRTLALRQRLRACLDTIHSFQEAHLDDECAFYTSRAPPPGPTRVFTNPVVTTLEWQDALRFVPIGPVVPQDSPS---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12815-1", "uniprot_id": "TROAP_HUMAN", "id": "Q12815-1", "name": "Tastin", "aln": "MTTRQATKDPLLRGVSPTPSKIPVRSQKRTPFPTVTSCAVDQENQDPRRWVQKPPLNIQR--PLVDSAGPRPKARHQAETSQRLVGISQPRNPLEELRPSPRGQNVGPGPPAQTEAPGTIEFVADPAALATILSGEGVKSCHLGRQPSLAKRVLVRGSQGGT--TQRVQGVRASAYLAPRTPTHRLDPARASCFSRLEGPG-----PRGRTLCPQRLQALISPSGPSFHPSTRPSFQELRRETAGSSR--------TSVSQASGLLLETPVQPAFSLPKGEREVVT--HSD-EGGVASLGLAQRVPLRENREMSHTRDSHDSHLMPSPAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPMPSTPRVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPPVATPSGPHSNRTPS---LQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDMVELQPLLTEISRTLNATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATTSLIFSSQHPLCASPPICSLQSLRPPAGQAGLSNLAPRTLALRERLKSCLTAIHCFHEARLDDECAFYTSRAPPSGPTRVCTNPVATLLEWQDALCFIPVGSAAPQGSP----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QC53-1", "uniprot_id": "E9QC53_DANRE", "id": "E9QC53-1", "name": "", "aln": "---MSSSNPLRAQNRSQQDQTGMLKSQDLRTKPSASSTKRGSENLDPSASAEAGKVVSKLKGVSRLPVLAKSLQPALSELSQNPNHNKWEQRPLAGKAQKKKTCTKPVPFNLSQSRTRIQKSTDVSQGKPPLMPSARLTTAEKLRDLNAGAKTDTQSHKTTTPGVLRTQANKSPRLQSFNNVHYKNSTDGHGCYNQTDLSSRLDCIHLSQSKHPEHSSHLSKASLSKVDVNSENQAPKDKHCFQTVPSTAQSHVSYKGSSQNLSSAVHNVFSREGLSAVGAQCMMPRLSTCPSGPGASNNLPQRVLKKTHHGVDATADKAG------------------------LFSPDPSALRSILQSDGTRLAEHTGATPRVSTCPTGRGTSIYSAQRVPVKKPQTEVSAAVKAPAGSAVSFSPDPAALRSILLNEGVRAGGATPSRVSVCPTGRGTSIYSAQRVPVKKNKQEVMVTAAVSSQCANRTPVMKWTPQRVTNTKPQSMRKLCTTQKMSSLRDSPGFLGSHDPSPGTLMCQEGEKVVQRLFEEQEQMDDDQTDQNGIAS----------------------QQLLNSHQS------------------------------------------VEAKSTVTENSDSNLHHTKNEGKKTAQPFIQAAHRGSVIVFSSSQRLVSEHSQDRLKTLAANLQLCEDRPTSHN-AAQSNGSQINPSVDMTKQSQSKAAITKSSAVSALRRRQTPLEEMFLDEECATYTSRLLSCPLQPRSGNPVASTLLFQDSTCFLPIGLSSPVRLSPVLSSGSIRA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:.: :. * .. : ** .:..* ..** ** .: : .. :. :* * :.** . . . . : . . . ..::.. :.:. . . :. .: : * * *. ::. : . :: .. .*:.: : .. .:: . : . * . .. . .:. . : :: .. ** :.. .. * : :. : * .*.**: : : * .: :. * . : .** : .*:: . .. . *: : : : : .. .: .: . *: . **: : :: . * . . .: . . . .: .* :. : * : . . : * : :: : . :.. . . : . : . * : . . : . . . .: . ::.* . : * . . . * *: .. : ::: . : : :.* **:*** **** . ***.: * :**: *:*:* * . ", "identical_positions": 62, "similar_positions": 204, "identity": "7.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1980", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q499U4-1", "uniprot_id": "DRC4_RAT", "id": "Q499U4-1", "name": "Dynein regulatory complex subunit 4", "aln": "MAPKRRGKKGKAKGNAVVDGVAPEDMSKEQVEEHVARIREELDREREERNYFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEHQNNLAEVKTEGTVVMKLAQKEHRAQEGALRKDMRVLKVELKEQELANEVVIKNLRLKQAEEITKMRNDFERQVREIEAKYDKKMKMLRDELDLRRKTEIHEVEERKNGQISTLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEEYLEREMAEVSLQNKRLAEPLQRAKEEMSEMQKRLGNHERDKQILACTKARLKVTEKELKDLKWEHEILEQRFIKVQQEREELYRKFTAAIQEVQQKTGFKNLVLERKLQALNAAVEKREVQFNEVLAASNLD-PTALTLVSRKLEDVLESKNTTIKDLQYELARVCKAHNDLLRTYEAKLLAFGIPLDNVGFKPLETAVIGQTLGQGPAGLVGAPT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60779-1", "uniprot_id": "DRC4_MOUSE", "id": "Q60779-1", "name": "Dynein regulatory complex subunit 4", "aln": "MAPKKKGKKGKAKGTAIVDGVAPEDMTKEQVEEHVARIREELDREREERNYFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEHQNNLAEVKAEGTVVMKLAQKEHRTQEGALRKDMRVLKVELKEQELANEVVIKNLCLKQAEEITKMRNDFERQVREIEAKYDKKMKMLRDELDLRRKTEIHEVEERKNGQISTLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEEHMEREMAEVTLQNRRLADPLQKAKDEMNEMQKRLGNHERDKQILVCTKARLKVAERELKDLKWEHEVLEQRFIKVQQEREELYRKFADAIQEVQQKTGFKNLLLERKLQALNAAVEKREVQFNEVLAASNLD-PTALTLVSRKLEDVLESKNTTIKDLQYELARVCKAHNDLLRTYEAKLLAFGIPLDNVGFKPLETAVIGQTLGQGPAGLVGAPT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95995-1", "uniprot_id": "DRC4_HUMAN", "id": "O95995-1", "name": "Dynein regulatory complex subunit 4", "aln": "MAPKKKGKKGKAKGTPIVDGLAPEDMSKEQVEEHVSRIREELDREREERNYFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEHQNNLTEMKAEGTVVMKLAQKEHRIQESVLRKDMRALKVELKEQELASEVVVKNLRLKHTEEITRMRNDFERQVREIEAKYDKKMKMLRDELDLRRKTELHEVEERKNGQIHTLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEDHLEREMAEVSGQNKRLADPLQKAREEMSEMQKQLANYERDKQILLCTKARLKVREKELKDLQWEHEVLEQRFTKVQQERDELYRKFTAAIQEVQQKTGFKNLVLERKLQALSAAVEKKEVQFNEVLAASNLD-PAALTLVSRKLEDVLESKNSTIKDLQYELAQVCKAHNDLLRTYEAKLLAFGIPLDNVGFKPLETAVIGQTLGQGPAGLVGTPT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QNW4-1", "uniprot_id": "DRC4_DANRE", "id": "F1QNW4-1", "name": "Dynein regulatory complex subunit 4", "aln": "MPPKRKSSP-KGKTPTVVDGLSTEEMSKEQLEEHIMRLREELDREREERNYFQLERDKIHTFWEITRRHLEENKCELRNRERELEEVEERHQVEIKVYKQKVKHLLYEQQNMLSELKAESIISTKLLQDEHADLEKEQWKDMRSLKLELKQQELSSENVLKRIHLKHDEETTDLRNDFARQVQEIGSKYEKRMQKLRQEEELRRKTEIHEIEERKNTHINMLMKNHEKAFRDIRNYFSDIVYKNLDLITSLKEELKEMKKNEEKRNKEMAEVLEQNKELKESSQKAKEQVAELQKQLANYEKDKSILTRSRARLKMSDREMKELKWELEVLEQRFSKVQLERDELYMKFTKAILEVQQKSGFKNLLLECKLNTLNDTLEKKEAQLSEVLSASNLD-PTTLSVVTHKLEEVLESKNHTIKDLQYEVARVCKAHNDLLKTSEAKLRAFGIPVEELCFEPLKSN--GQSVGQGPAMFVSSSN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MT08-1", "uniprot_id": "DRC4_DROME", "id": "Q8MT08-1", "name": "Dynein regulatory complex subunit 4", "aln": "MPPKGKKGKKGKKLPVLIDGVDTSAMTRDQLEAFALRLKAEMDREREERNYFQLERDKIRTFWEITRQQLDETRYELQQKDKEIEATQDLADIDTKHVMQQMKHLQFENHNRLGEVRAEAMTQLKLAQEHHVLQENELQRDKRQLRRMLRERMEMSEMQLRQMEAHFNEKLLEQRITFERERKDNEMLHEEKMIEQKAKLDLFYGTQMFEVEERKNQQIKDLQDHHDLAFNDMKNYYNDITLNNLALIGSMKEQLEHLRKQAERSDRIAADTAAENRRLKEPLEHANIQLNEYRRKLEFYERDKQQLSRLKTRNTRLEKKVKGLTWEAETLILRNDSLVAEREGLKERFNDVIVELQQKTGLKNVLLERKIAALMREDEKRSIVLHETIATCAPNFAEKLTSLDERVGNIIDEKNKIILDLRYEVTKARKAHDDLLETYECKLKQYGVPTDELGFKPIRNRDQQQLYVCGPAGIITENK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.** : * ::**: .. *:::*:* . *:: *:*****************:*******::*:*.: **:::::*:* .:: ::: * *::*** :*::* * *:::*. ** *..* * :* * *: *::: .* ::.: : *: * * *: :: ::::* : : :* *::.*:***** :* * ..*: ** *::**:.**. :** ** *:**:::.::*: : :: *:. :*:.* :. ::*. :: * :::* :*:**. * ::* . ::::* * ** * * * .: **: * :* .* *:***:*:**::** *: :* **:. : *.:::. : . *: : .:: ::::.** * **:**:::. ***:***.* *.** :*:* ::: *:*:.. * *** :: .", "identical_positions": 155, "similar_positions": 168, "identity": "32.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1986", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M1X2-1", "uniprot_id": "A0ABK0M1X2_RAT", "id": "A0ABK0M1X2-1", "name": "CD99 antigen-like protein 2", "aln": "--MVARLTTLLVCLVFSLATLVQRGPRDQTRVIRLEGYGDFDDFNLEDALKETSSVKQ--SHFSTTTR-RTGTTRAPANP-------------------------AERWDHMTTTTTKRPGTTRAPSNPLELDGFDLEDALDDRNDLD-GPKKPSTGE----------------GGGLSDKDLEDILG-GGGYKPDKNKGGGGGYGSQD---DPGSG----AVTDPGTIAGLVSALAAALLGAVSGYLSYQHRKFCFSVQRGLDAAYVKGENLEAVVCEEPRVEAAMCEAPPVTDSTQHSQPTEPLAP-ERPRI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BIF0-1", "uniprot_id": "C99L2_MOUSE", "id": "Q8BIF0-1", "name": "CD99 antigen-like protein 2", "aln": "--MVARLTAFLVCLVFSLATLVQRG------------YGDTDGFNLEDALKETSSVKQRWDHFSTTTR-RPVTTRAPANP-------------------------AERWDHVATTTTRRPGTTRAPSNPMELDGFDLEDALDDRNDLD-GPKKPSAGE----------------AGGWSDKDLEDIVE-GGGYKPDKNKGGGG-YGSND---DPGSG----ISTETGTIAGVASALAMALIGAVSSYISYQQKKFCFSIQQGLNADYVKGENLEAVVCEEP----------QVTYSKQETQSAEPPPP-EPPRI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TCZ2-1", "uniprot_id": "C99L2_HUMAN", "id": "Q8TCZ2-1", "name": "CD99 antigen-like protein 2", "aln": "--MVAWRSAFLVCLAFSLATLVQRG------------SGDFDDFNLEDAVKETSSVKQPWDHTTTTTTNRPGTTRAPAKPPGSGLDLADALDDQDDGRRKPGIGGRERWNHVTTTT-KRPVTTRAPANTLGND-FDLADALDDRNDRDDGRRKPIAG-----------------GGGFSDKDLEDIVG-GGEYKPDKGKGDGR-YGSND---DPGSG----MVAEPGTIAGVASALAMALIGAVSSYISYQQKKFCFSIQQGLNADYVKGENLEAVVCEEP----------QVKYSTLHTQSAEPPPPPEPARI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DBW9-1", "uniprot_id": "C99L2_DANRE", "id": "Q6DBW9-1", "name": "CD99 antigen-like protein 2", "aln": "--MEKTLWTWTLLAVFSL--LVVKG--------------MSDGLDLADALGDDDDDEPTTKPPKADPG-AGGAGGAAVKP----------------------------TLKPVKPTVKEPAKPKP--KQTGLDDFDLADALNPDNDIKGKGKDSGKGDKEVGGGSRDDGTPNSRGSQFSDDDLLDVGN-DNSYKPDKGKGGKGGSSSNVGDLDPADDNNYDTMAETGTIAGIVSAVAMALVGAVSSYISYQKKKLCFSIQQSLNADMVKADAPDAVVAQEP----------QVQQTLLQPPNAEPPTEENAV--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8VCN6-1", "uniprot_id": "CD99_MOUSE", "id": "Q8VCN6-1", "name": "CD99 antigen", "aln": "MARAAMEAAATVVLALALLGAAARG-------------AASDDFNLGDALEDPNMKPTPKAPTPKKPS--GGFDLEDALP--------------------------------------------------GGGGGGAGEKPGNRPQPDPKPPRPHGDS-----------------GGISDSDLADAAGQGGGGAGRRGSGDEGGHGGAGG--AEPEG------TPQGLVPGVVAAVVAAVAGAVSSFVAYQRRRLCFREGGSAPV-------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .::* . :* *.::* **: : . . . * . . : . : . . . . **.** * .. :..*. .. .. : * :.*:.:*:. *: ****.:::**::::** . . ", "identical_positions": 25, "similar_positions": 54, "identity": "7.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1988", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NZU0-1", "uniprot_id": "FLRT3_HUMAN", "id": "Q9NZU0-1", "name": "Leucine-rich repeat transmembrane protein FLRT3", "aln": "MISAAWSIFLIGTKIGLFLQVAPLSVMAKSCPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGLMCQAPEKVRGMAIKDLNAELFDCKDSGIVSTIQITTAIPNTVYPAQGQWPAPVTKQPDIKNPKLTKDHQTTGSPSRKTITITVKSVTSDTIHISWKLALPMTALRLSWLKLGHSPAFGSITETIVTGERSEYLVTALEPDSPYKVCMVPMETSNLYLFDETPVCIETETAPLRMYNPTTTLNREQEKEPYKNPNLPLAAIIGGAVALVTIALLALVCWYVHRNGSLFSRNCAYSKGRRRKDDYAEAGTKKDNSILEIRETSFQMLPISNEPISKEEFVIHTIFPPNGMNLYKNNHSESSSN-RSYRDSGIPDSDHSHS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BGT1-1", "uniprot_id": "FLRT3_MOUSE", "id": "Q8BGT1-1", "name": "Leucine-rich repeat transmembrane protein FLRT3", "aln": "MISPAWSLFLIGTKIGLFFQVAPLSVVAKSCPSVCRCDAGFIYCNDRSLTSIPVGIPEDATTLYLQNNQINNVGIPSDLKNLLKVQRIYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPGGLPRTIEELRLDDNRISTISSPSLHGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGTSLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGLMCQAPEKVRGMAIKDLSAELFDCKDSGIVSTIQITTAIPNTAYPAQGQWPAPVTKQPDIKNPKLIKDQRTTGSPSRKTILITVKSVTPDTIHISWRLALPMTALRLSWLKLGHSPAFGSITETIVTGERSEYLVTALEPESPYRVCMVPMETSNLYLFDETPVCIETQTAPLRMYNPTTTLNREQEKEPYKNPNLPLAAIIGGAVALVSIALLALVCWYVHRNGSLFSRNCAYSKGRRRKDDYAEAGTKKDNSILEIRETSFQMLPISNEPISKEEFVIHTIFPPNGMNLYKNNLSESSSN-RSYRDSGIPDSDHSHS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B8A507-1", "uniprot_id": "B8A507_DANRE", "id": "B8A507-1", "name": "Leucine-rich repeat transmembrane protein FLRT3", "aln": "MASNYMSFFVFFIRAGLLLGLANPLMTSASCPSQCRCDGTFIYCNDRDLTSIPSGIPEDATVLFLQNNRIKSAGIPTDLRRLNGVEKIYLYCNNLDEFPTNLPLNVKELHLQENNIRTITHASLAQIPFIEELHLDDNSVSAVSIEEGAFRDSNHLRLLFLSRNHLSTIPSGLPMTIEELRFDDNRISSISEASLQDLINLKRLVLDGNLLNNRGIGEMALVNLVNLTELSLVRNSLTSPPANLPGSSLEKLNLQDNHINHVPPGAFAFLRQLYRLDLSGNNLSSLPMGVFEDLDNLTQLLLRNNPWHCNCRMKWVRDWLRTLPSKVNVRGFMCQGPDKVKGMAIKDLSTELFGCSDTEIPTTYETST-VSNTLPPSRPQWPSYVTKRPVVKGPDLGRNYRSTTPSSRKIITISVKSSSAETVHISWRVSQPMTALRLSWLKLGHSPAFGSITETIVQGERTEYLLTALEPESSYRICMVPMETSNIYLSDETPVCIETETGSLKAYNPTTTLNREQEKEPYKNSNLPLASIIGGAVALLAIIMLALVCWYVHRNGSLFSRNCTYNKGRRRKDDYAEAGTKKDNSILEIRETSFQMIPINHMPVSKEEFVIHTIFPPNGLSLYKSPHSENSINNRSYRDSGIPDSDYSHS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * *:*:: : **:: :* : : **** ****. ******* ***** *******.*:****:*:..***:**:.* *::**** *.********* ***************: **::**::************************:*************** *** ******:******:**..**:.* .*************:*:*: .:.****************:.*.****:.*.** *******:***.**::********:*.****.** *:*:****:***:******:*.*:********::** ******:***.*:**:*******.:***.*.*: * :* : :* :.** *:: ***: ***:* :*.*.* :: ::* ..*** * *:*** :.:*:****::: ************************** ***:***:*****:*.*::*********:** *********:*..*: ******************.*****:********::* :*******************:*.******************************:**.: *:***************:.***. **.* * ************:***", "identical_positions": 469, "similar_positions": 125, "identity": "72.15%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1989", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q05516-1", "uniprot_id": "ZBT16_HUMAN", "id": "Q05516-1", "name": "Zinc finger and BTB domain-containing protein 16", "aln": "------------------------------MDLTKMGMIQ-----LQNPSHPTGLLCKANQMR----LAGTLCDVVIMVDSQEFHAHRTVLACTSKMFEILFHRNSQHYTLDFLSPKTFQQILEYAYTATLQAKAEDLDDLLYAAEILEIEYLEEQ--------------------------------------CLKMLETIQASDDNDTEATMADGGAEEEEDRKARYLKN---IFIS-KHSSEESGY-----------ASVAGQSLPGP-MVDQSPSVSTSFGLSAMSPTKAAVDSLMTIGQSLLQGTLQPPAG-----------------------------PEEPTLAGGGRHPG----------------------VAEVKTEMMQVDEVPSQDSPGAAESSISG-GMGDKVEERGKEGPGTP---------------------TRSSVITSARELHYGREE-SAEQVPPPAEAGQAPTGRPEHPAPPPEKHLG-IYSVLPNHKADAVLSMPSSVTSGLHVQP--------ALAVSMDFSTYGGLLP--------------------------------------QGFIQRELFSKLGELAVGMKSESRTIGEQCSVCGVELPDNEAVEQHRKLHSGMKTYGCELCGKRFLD-SLRLRMHLLAHSA--GAKAFVCDQCG--AQFSKEDALETHRQTHTGTDMAVFCLLCGKRFQAQSALQQHMEVHAGVR-----SYICSECNRTFPSHTALKRHLRSHTG-DHPYECEFCGSCFRDESTLKSHKRIHTGEKPYECNGCGKKFSLKHQLETHYRVHTGEKPFECKLCHQRSRDYSAMIKHLRTHNGASPYQCTICTEYCPSLSSMQKHMKGHKPEEIPPDWRIEKTYLYLCYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5S3S9-1", "uniprot_id": "Q5S3S9_RAT", "id": "Q5S3S9-1", "name": "", "aln": "------------------------------MDLTKMGMIQ-----LQNPSHPTGLLCKANQMR----LAGTLCDVVIMVDSQEFHAHRTVLACTSKMFEILFHRNSQHYTLDFLSPKTFQQILEYAYTATLQAKAEDLDDLLYAAEILEIEYLEEQ--------------------------------------CLKILETIQASDDNDTEATMADGGGEEEEDRKARYLKN---IFIS-KHSGEESGY-----------ANVAGQSLPGP-MVDQSPSVSTSFGLSAMSPTKAAVDSLMTIGQSLLQGALQPPAG-----------------------------PEEPTLAGGGRHPG----------------------VAEVHMEMMQVDEAPGQDSPGAAESSVSG-GMGDKLEERSKEGPGTP---------------------TRGSVITSARELHYGREE-SGEQLSPPVEAGQGPPGRQESLAPPVEKHLG-IYSVLPNHKADAVLSMPSSVTSGLHVQP--------ALAVSMDFSTYGGLLP--------------------------------------QGFIQRELFSKLGELAVGMKAESRPLGEQCSVCGVELPDNEAVEQHRKLHSGMKTYGCELCGKRFLD-SLRLRMHLLAHSA--GAKAFVCDQCG--AQFSKEDALETHRQTHTGTDMAVFCLLCGKRFQAQSALQQHMEVHAGVR-----SYICSECNRTFPSHTALKRHLRSHTG-DHPYECEFCGSCFRDESTLKSHKRIHTGEKPYECNGCGKKFSLKHQLETHYRVHTGEKPFECKLCHQRSRDYSAMIKHLRTHNGASPYQCTICTEYCPSLSSMQKHMKGHKPEEIPPDWRIEKTYLYLCYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q802Y8-1", "uniprot_id": "ZB16A_DANRE", "id": "Q802Y8-1", "name": "Zinc finger and BTB domain-containing protein 16-A", "aln": "------------------------------MDLTKMGMIQ-----LQNPNHPNALLHKANQMR----LAGTLCDVVIMVDSQEFHAHRTVLACTSKMFEILFHRNSQHYTLDFLSPKTFQQILEYAYTATLQAKVEDLDDLLYAAEILEIEYLEEQ--------------------------------------CLKILETIQSSDENDTEVNMNDGGTEDDEERKGRHGRN---LVGSKKHSTEESGY-----------VSAAQQALALPGMVDQSPSVSTSFGLSTMSPTKAAVDSLMSIGQSLLQSTMHPGVG-----------------------------AEQP--LHGNSHPM----------------------MGEIKTEMMQVDESGEHESPKAMESIASSNGERSGEPDKNRDGPGTP---------------------TRSSVITSARELHYVRDEGLGDQQAEVSQMG------LEAMAGMTEKHLASLYGIPSNHKNEAMLSMPASMASSLHMSP--------ALAMSMDFSAYGGLLP--------------------------------------QSFIQREFFSKLGELAAGIKPDGRSLNERCNVCGAELPDNEAIEQHRKLHSGMKTYGCELCGKRFLD-SLRLRMHLLSHSA--GEKAIVCDQCG--AQFQKEDALEAHRQIHTGSDMAIFCLLCGKRFQTQTALQQHMEVHAGVR-----SYICSECNRTFPSHTALKRHLRSHTAGDHPFECEFCGSCFRDESTLKGHKRIHTGEKPYECNGCGKKFSLKHQLETHYRVHTGEKPFECKLCHQRSRDYSAMIKHLRTHNGASPYQCTICLEYCPSLSAMQKHMKGHKPEDIPPDWRIEKTYLYLCYV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P47043-1", "uniprot_id": "ZAP1_YEAST", "id": "P47043-1", "name": "Zinc-responsive transcriptional regulator ZAP1", "aln": "MDALTPRDSPKRDDSMATSAATAASAKPDALTIGKEGIVHGHIHNYNNLTYIHGHLHHSAPVNDSSASATPAAAAVADAATSAFASGASHDMGGDCHVNEKCKEYTDCQHFEFLNYHNNPSLTKYNDTATYNSNNHSFANNFHSVASDPTSPQQNSKSDLPRRKDSWFNDDLILLPSSKKNKPNPPPGSDDCYCTPKILEICCDETHPKSEANIKQGESDQPTKKDISENGNDVAIFTDVKNDHLMPNFNLHDQYCNSTNHDSHNHNNTVPDSFSQLMSHLSEIDCDLTCDTPCTASTSATSGHKFVQDHQSSNNDDVFHKYCKFCEESTDNQPCSKHMHLESKPPQLPPKCSSLRKPTNTLQGTNHAYHEHILNTDMDLKILEDLCNISSLYEVPFGKHINHHDHNNAGNGCDGSSTGNNENGNQTMNLLLSSINRCNPKNNLNGSNNNTAGATSTDHQHHHHRIQFHSHKPNRNNIVNNSGISAANTTADLTNNDLNDLISREYSYERFRNQSEPPSLPKVTHQNQKNRRSWPTKDLESTDFSSLEDSLPSSISPPIQTTSTINFNWCFKEEKNNDLKCKWKECPESCSSLFDLQRHLLKDHVSQDFKHPMEPLACNWEDCDFLGDDTCSIVNHINCQHGINFDIQFANPDSFLPGSISKEKHHLLHCP--NPQTHEVSKADGAPDMTSANDVSNIPPIKQPEQVICQWDGCNKSFSSAQELNDHLEAVHLTRGKSEYQCLWHDCHRTFPQRQKLIRHLKVHSK-YKPYKCKTCKRCFSSEETLVQHTRTHSGEKPYKCHICNKKFAISSSLKIHIRTHTGEKPLQCKICGKRFNESSNLSKHIKTHQ--KKYKCSDCSKSFDDLGKLNSQKVKCALE--------RKPYL-----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39933-1", "uniprot_id": "TF3A_YEAST", "id": "P39933-1", "name": "Transcription factor IIIA", "aln": "-----------------------------------------------------------------------------------------------------------------------------MGGEVLNNEGMPLAELKQETIPISRSESSES---------------------------------------LNSLTSTRSSSSNRPKTYFCDYDG--------------------------------------------CDKAFTRPSILTEHQLSVHQG----LRAFQCDKCAKSFVKKSHLERHLYTHSD------------------------------------------------------------------------------------TKPFQCSYCGKGVTTRQQLKRHEVTHTK---------------------SFICPEEGCNLRFYKHPQLRAHILS-------------VHLHKLTCPHCNKSFQRPYRLRNHISKHHDPEVEN--------------------------------------------------------------------------------------------PYQCTFAGCCKEFRIWSQLQSHIKNDH--PKLKCPICSKPCVG-ENGLQMHMIIHDDSLVTKNWKCHICPDMSFSRKHDLLTHYGSIHTEEDIPLELKYKIS--DIQQLVQDHGVQLGNSK-----HSNEQDEEKISNRLRKRRKLTENNNVEFLQNEVDLEKRLESGENGLNLLLNTVGRKYRCFYNNCSRTFKTKEKYEKHIDKHK-VHELKLKILQEKEEN-----KTLVDQNHKEPFIIQKETQSAGDK-------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : : . . .:. : * . .:. : : : . * . : . . : :. :: . . : .. * . .: * . . .: : : .. . . ..: . . * : .* : . . : . . * : * : . . . : : : :: . . :::* : : .: : . :. : . .*. * . : : *.:.* . . : * *. : :: *: :: .: * : :: . : : . ", "identical_positions": 17, "similar_positions": 111, "identity": "1.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-1998", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BMK0-1", "uniprot_id": "CEP85_MOUSE", "id": "Q8BMK0-1", "name": "Centrosomal protein of 85 kDa", "aln": "MAMQEKYPND-RSHATSPGSNVIQKGSSLGTEWQTPVISETFRSRFSRCSSIADSGDTAIGTSCSDIAEDFCSSSGSPSFQPIKSHITIPTAHVMPSTLG--ASPAKPNSAPSG--PSSAKLPLSGLTEGVGMTRNGDFGAVKRSPGLARDFMYLPSAAGENGSQQSWFPAVGHEREGEMRKFDVPSMESTLNQPAMLETLYSDPHYRAHFPNPRPDT--NKDVYKVLPESKKAPGSGAVFERNGPHASSSGVLPLGLQPAPGLSKSLSSQVWQPSPDPWHPGEQSCELSTCRQQLELIRLQMEQMQLQNGAMCHHPAAFAPLLPTLEPAQWLSILNSNEHLLKEKELLIDKQRKHISQLEQKVRESELQVHSALLGRPAPFGDVCLLRLQELQRENTFLRAQFAQKTEALSKEKMELEKKLSASEVEIQLIRESLKVTLQKHSEEGKKQEERVKGRDKHINNLKKKCQKESEQNREKQQRIETLERYLADLPTLEDHQKQTEQLKDAELKNTELQERVAELETLLEDTQATCREKEVQLESLRQREADLSSARHSFQD--KQSVEEAN------GENLRVDMESQQKECDSLRKMVERQQLKMEQLHSQVQSQKQELAQEEGINQALREEAQRRETALQQMRTAVKELSVQNQDLIEKNLTLQEHLRQAQPGSSS--SPDSAQLACELHQELASCLQDLQAVCSIVTQRAQGHNPNLSLLLGIHSTQHP--GTQLDLQKPDVIRRKLEEVQQLRHDIEDLRTSLSDRYAQDMGENCATQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P2H3-1", "uniprot_id": "CEP85_HUMAN", "id": "Q6P2H3-1", "name": "Centrosomal protein of 85 kDa", "aln": "MAMQEKYPTEGISHVTSPSSDVIQKGSSLGTEWQTPVISEPFRSRFSRCSSVADSGDTAIGTSCSDIAEDFCSSSGSPPFQPIKSHVTIPTAHVMPSTLG--TSPAKPNSTPVG--PSSSKLPLSGLAESVGMTRNGDLGAMKHSPGLSRDLMYFSGATGENGIEQSWFPAVGHERQEEARKFDIPSMESTLNQSAMMETLYSDPHHRVRFHNPRTST--SKELYRVLPEAKKAPGSGAVFERNGPHSNSSGVLPLGLQPAPGLSKPLPSQVWQPSPDTWHPREQSCELSTCRQQLELIRLQMEQMQLQNGAICHHPAAFGPSLPILEPAQWISILNSNEHLLKEKELLIDKQRKHISQLEQKVRESELQVHSALLGRPAPFGDVCLLRLQELQRENTFLRAQFAQKTEALSREKIDLEKKLSASEVEVQLIRESLKVALQKHSEEVKKQEERVKGRDKHINNLKKKCQKESEQNREKQQRIETLERYLADLPTLEDHQKQSQQLKDSELKSTELQEKVTELESLLEETQAICREKEIQLESLRQREAEFSSAGHSLQD--KQSVEETS------GEGPEVEMESWQKRYDSLQKIVEKQQQKMDQLRSQVQSLEQEVAQEEGTSQALREEAQRRDSALQQLRTAVKELSVQNQDLIEKNLTLQEHLRQAQPGSPP--SPDTAQLALELHQELASCLQDLQAVCSIVTQRAQGHDPNLSLLLGIHSAQHP--ETQLDLQKPDVIKRKLEEVQQLRRDIEDLRTTMSDRYAQDMGENCVTQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QBC3-1", "uniprot_id": "E9QBC3_DANRE", "id": "E9QBC3-1", "name": "", "aln": "MTTSQKYQSSELTGLS-------------DMEWATPAVSEKFQSRFGWRPSKVDSGDMGLGT--FDHTEEICSSRSSPCFQPIRSQIPIPTAHVMPSTAGALASKLKPHSSEEGRTTSSSSSSKSSLSKSASSPNLDAQHDENLDTTSVKPDCLSRYRSLVNGLDHSLFPSGDQTRLDEPQKFDVPTMEPTLNQSALLGGLYPDVCQQLQLTGPADNAGLHDQTYKVLPESRACP-VDPYSQRSMYSGSGTSARMFSIPQGLQTQALLRDQACTYDQLLQERCGELASWQQQKQKLETLRLQVEQMQLMTGGSGQYLPLY-PSAAHTENSKWDAVIKANENLLKDKELTIERQKQQMSQLEQRLRESELQVHSALMGRGAPYTDVCLLRLQEAQRENAFLRAQFAERNNCFTKDKLEADRRLGAVETEMQRLNEVLKESSEKHAEELKKQEERIRSRDKHINGLKKKCQKEAEQNREKQQRIETLERYLADLPTMEDYQAQHKKLEEVEERAAELQSTVKDLEVQLEAAHTAVRNKETQLEEQRRKERELLTTVTSLQNRVQESLEDGVRLPSLDIEKLREENTALKDEQQRLKKVIEKQLRMMEQLGSQIRTLEEQISQEECISQALRQETADKEQNLLQLRSAMKELSVQNQELMEHNLTLQERLQGEEPSSGCGLLPAGARLTQRLHGEMAACLCDLRSLCNVLTQRAQGHDPNLSMLLGIASAPPPVAEQWDDWLSPEGLQKKLNEAQQLRRDVEELRTTVSDRYAQDMGENCITQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .:** .. : : . ** **.:** *:***. .* .**** .:** * :*::*** .** ****:*::.********** * :* **:*: * .**:. . *.*::... .. . : .. : : ** ::* **: .: * * :***:*:**.****.*:: **.* : :: .* .: .: *:****:: .* .. :*. ...:.. :.: . . * .*. . . : .. . :*:** :***:***** .*. :: . : * . * ::* :::::**:***:*** *::*::::*****::***********:** **: ********* ****:*******::.:.::::*:: :::*.* *.*:* :.* ** : :**:** ******::.******.********:**********************:**:* * ::*:: * : :***. * :** ** ::: *:** ***. *::* :: :: *:*: ::*:*: * . : : :.. : *:*::*:* *:** **::: :::::*** .****:*: :: * *:*:*:********:*:*:******:*: :*.* * *:*: .** *:*:** **:::*.::*******:****:**** *: * * .*: :::**:*.****:*:*:***::************ **", "identical_positions": 327, "similar_positions": 239, "identity": "41.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-202", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAM8-1", "uniprot_id": "F1MAM8_RAT", "id": "F1MAM8-1", "name": "Probable ATP-dependent RNA helicase DDX20", "aln": "-MAAAFEALPASTTSESAMAAELEAAPVPAAEPTPASPWNLRTAHDIGGPRTRTGDVVLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDSLILENYSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKKCHIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEE---GSFQEQINWIYSSLPASKQMLAVSATYPEILANALTRYMRDPTFVRLNPSDPSLIGLKQYYQVVNSYPLAHKIFEEKTQHLQELFSKIPFNQALVFSNLHSRAQHLADILSSKGFPTECISGNMNQNQRLDAMAKLKQFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMKIAQKCN--INLLPLP-DPIP------------------AGLMEECLDCDVEVKAAMHTYSSPSISTQSPKKQVQKPERAFQSQRTPGSHMPSPRNTSVSTLSAKSKHG-KQKLPVKSHSECGILEKAAPPQELGCTTHPEEQVKNSVQTSTEESSSNSLHQ---------------------------------------AKETSPGSLPKIPCLSSFKVHQL----------------------------------SALTFAELVEDYEHYIKE-----------------GLEKPVEIIRHYTGPGAQTVNPQNGFVRNRVSADRVQMLVSSSQSGDSESESDSCSSRTS---------------------------------------------------------------------------------------------SQSKGNKSYLEGSSDTQLKDSECTSVGGPLSLEQIQNG-------NDTSTQVEYQESPETQVKARHKEGANQ----------RSKPSRRNPPRRSSYRVQTE-AQEEGWHDCHRETNASSSDPYQDYEEYWRAYYRAWQEYYAAASHSYYWN--------------AQRHPSWMAAYHMNTVYLQEMMRGNQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJY4-1", "uniprot_id": "DDX20_MOUSE", "id": "Q9JJY4-1", "name": "Probable ATP-dependent RNA helicase DDX20", "aln": "MAAAAFEVPAALTTSESTMAAERAAAPVQAVEPTPASPWTQRTAHDIGGPRTRTGDVVLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDSLILENYSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKKCHIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEE---GSFQEQINWIYSSLPASKQMLAVSATYPEVLANALTRYMRDPTFVRLNPSDPSLIGLKQYYQVVNSYPLAHKIFEEKTQHLQELFSKVPFNQALVFSNLHSRAQHLADILSSKGFPTECISGNMNQNQRLDAMAKLKQFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMKIAQKCN--INLLPLP-DPIP------------------PGLMEECLNWDVEVKAAMHTYSSPTVATQSPKKQVQKLERAFQSQRTPGNQTPSPRNTSASALSARPKHS-KPKLPVKSHSECGVLEKAAPPQESGCPAQLEEQVKNSVQTSVEDSSSNSQHQ---------------------------------------AKDSSPGSLPKIPCLSSFKVHQP----------------------------------STLTFAELVDDYEHYIKE-----------------GLEKPVEIIRHYTGPEAQTGNPQNGFVRNRVSEDRAQMLVSSSQSGDSESDSDSCSSRTS---------------------------------------------------------------------------------------------SQSKGNKSYLEGSSDTQLKDTECTPVGGPLSLEQVQNG-------NDTPTQVEYQEAPETQVKARHKEGANQ----------RSKQSRRNPARRSSYRVQSE-PQEESWYDCHRETTASFSDTYQDYEEYWRAYYRAWQEYYAAASHSYYWN--------------AQRHPSWMAAYHMNTVYLQEMMRGNQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHI6-1", "uniprot_id": "DDX20_HUMAN", "id": "Q9UHI6-1", "name": "Probable ATP-dependent RNA helicase DDX20", "aln": "-MAAAFEASGALAAVATAMPAEHVAVQVPAPEPTPGPVRILRTAQDLSSPRTRTGDVLLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDSLVLENLSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKKCHIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEE---GSFQEQINWIYSSLPASKQMLAVSATYPEFLANALTKYMRDPTFVRLNSSDPSLIGLKQYYKVVNSYPLAHKVFEEKTQHLQELFSRIPFNQALVFSNLHSRAQHLADILSSKGFPAECISGNMNQNQRLDAMAKLKHFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMRIAQKCN--INLLPLP-DPIP------------------SGLMEECVDWDVEVKAAVHTYGIASVPNQPLKKQIQKIERTLQIQKAHGDHMASSRNNSVSGLSVKSKNNTKQKLPVKSHSECGIIEKATSPKELGCDRQSEEQMKNSVQTPVEN-STNSQHQ---------------------------------------VKEALPVSLPQIPCLSSFKIHQP----------------------------------YTLTFAELVEDYEHYIKE-----------------GLEKPVEIIRHYTGPGDQTVNPQNGFVRNKVIEQRVPVLASSSQSGDSESDSDSYSSRTS---------------------------------------------------------------------------------------------SQSKGNKSYLEGSSDNQLKDSESTPVDDRISLEQPPNG-------SDTPNPEKYQESPGIQMKTRLKEGASQ----------RAKQSRRNLPRRSSFRLQTE-AQEDDWYDCHREIRLSFSDTYQDYEEYWRAYYRAWQEYYAAASHSYYWN--------------AQRHPSWMAAYHMNTIYLQEMMHSNQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PQW1-1", "uniprot_id": "A0A8M9PQW1_DANRE", "id": "A0A8M9PQW1-1", "name": "Probable ATP-dependent RNA helicase DDX20", "aln": "--MCAQEGAVIHSSCHLFTVEETERCRDRNMAAS------VKAAHELQS-RTRTDDVLISGGVEFSSLLLSKPVLEGLSASGFQRPSPIQLKAIPLGRCGLDLIVQAKSGTGKTCVFTTIALDSLILENATTQVLVLAPTREIAVQIHAVVMAIGSAMEGLECHVFIGGRPISQDKQHLKKCHIAIGSPGRIKQLIEMGALMVSSIRLFVLDEADKLLEDDSSSSFQEQINWIYSSLPANKQMLALSATYPESLAQQLSRYMREPTFVRLNPTDPGLLGLKQYYKIVPSHSLPHKVFEEKVQSLLELFSKIPFNQALVFSNLHTRAQHLADILSSKGLPAVCISGGLSQDQRLEAMWKLKQYQCRVLISTDLTSRGIDAEKVNLVINLDVPQDWETYMHRIGRAGRFGTLGVAVTYCCHGEEENKMMAIAQKCS--LDLMHLP-DPIP------------------PGIMEEACDHDVII----ETLSKPKIPDN-FKPEKKKKAKSEQMKSKP------SRESHISVVITESVTG------DKSCSRAETKTKNHSSK-------PGRQKQMAPAANLQHDSTITQKQ---------------------------------------QND----TLPKIPPLSSFKSHTG----------------------------------KRITFDDALVDYETFIRE-----------------GPGRSVEIIHQYDGFYRSQDKVNGLHDAHDEDEASESYVLEESQSHQDLPPAQEVSELSS---------------------------------------------------------------------------------------------EQKTSSESSSE--SEMEVESESSSSVPSKSTLEALPDNKVSLVRNHSELAELALPSTRVPQQATRSKKRPCQP---------QSQDTAHHHNLPHKHRTASK-SSRRPTGPKRRTRETDETEEEEAGQDYWSS-YRAWAEYYN----SYYHH--------------SPYN--WMTAFYMNSVYIKEMMKH------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3C4-1", "uniprot_id": "DDX20_DROME", "id": "Q9V3C4-1", "name": "DEAD-box RNA helicase gemin3", "aln": "--------------------------------------MEREIAHSLAGGEERSSDVAPGQVKTFEELRLYRNLLNGLKRNNFVTPTKIQAAAIPMALAKMDLIIQSKSGTGKTLIYVIAVVQSFNPNINQPHAMIVVPTRELAIQVQDTFFHLCKSFRDFKCSAFIGGTDVAKDRKRMNESRVIIGTPGRLLHLYENRVFDVSKLRLLVLDEADQLYQT---KSLQHTVSKLIEAMPKNRQIIACSATYDQNLDERLAKVMDKPMLISNSERATVLLGIRQFVYELPQQNNSVEEMRLKLQILGQIFNQLPYEQAIIFASSQMRADSYKNYLTASGIDCHLISGAMEQSERLHVFEGYRNFTMRILVATDLMARGVDSPHANLVINIDPPQDHVTYLHRIGRAGRFGSKGIAITFIASKKESQRFREMSKKIATAWSVLEFPKEPMPNEFNFWDFEKYNFDYYIKEENPLQEMPMPIKENRSKENVDASSVDLENLQKDQDGKRRDPDKLPVALENVETQKELELENLPESSHNNKNLRVKEKEIVRQGKLKETNSKAGGSKTNKTERRKKSNTPSKLQKQITEVQQTPEITVNKYYMQEDIQRTADGKEYHPVNGAGNHQVPSKSNQKPVEFISPELTPTLTPLELTQEPSPTTVTPPAPPANSINNKTYCLAAPTQTSSMTIQNMVISNTVDDASSISSDSMVVCGYHSDRSYDTYYATSDEEEIWNRLMSKQRRQLKSKRGHGKRRVILYKKVFPKLKANVKRKLKKRMSSSCRSKKAHHLRKRHVYKNISLLPHMNLCHLLQKFTNQERFLKRLHKYAKNQFIDNARVGFLLDKLYKSILEMYYNSAKERKKHFKEAMKESLKSIDNYESQESSESEEEEEEEKDLKNKLSVHVTNQMDIPPMPQAAVEIGSGSESDTEDSQEYGEGEEIIVDDEDDGSDGGPNSSSGFVESQESVSSGIDTSVYETESTGASGNNSSAFFISDDESDTESLTDSEAGSNVSATGSSSQRSSVASSTYESSDDDSVTVTNVSSMQNAQSLWLQTFNMQYQFIASHVAKNLQNYY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:.: . . *:.** . *..* * : :*:** .* *: :* ***:. . :***:*:******* :: .::*: : .: :::.****:*:*:: .. : :..::* .**** :::*: ::::.:: :*:***: :* * : ..:**::*****:* : *:*. :. : .::* .:*::* **** : * : *:: * .* :: . . *:*::*: : . . : :. * * * ::*.::*::**::*:. : **: : *::.*: *** :.*.:**..: ::: *:*::*** :**:*: :.***:*:* * * **:**********: *:::*: . :*.: : :::* .:: :* :*:* : : .. . ..: : : : . : : :: . : . . *. . : . .: : : :. : : : : * *:.:: :.: : : * . : . ** .: . : : . . .:: . . * :. ... ..:* * .: :::. . * . : : . : . :. : .:: : .. : .. . :: : . . * * : *: :: *: :: . : ", "identical_positions": 136, "similar_positions": 267, "identity": "12.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2022", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62857-1", "uniprot_id": "RS28_HUMAN", "id": "P62857-1", "name": "Small ribosomal subunit protein eS28", "aln": "MDTSRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLTLLESEREARRLR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62858-1", "uniprot_id": "RS28_MOUSE", "id": "P62858-1", "name": "Small ribosomal subunit protein eS28", "aln": "MDTSRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLTLLESEREARRLR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62859-1", "uniprot_id": "RS28_RAT", "id": "P62859-1", "name": "Small ribosomal subunit protein eS28", "aln": "MDTSRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLTLLESEREARRLR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PBK3-1", "uniprot_id": "RS28_DANRE", "id": "Q6PBK3-1", "name": "Small ribosomal subunit protein eS28", "aln": "MDASRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDSNRSIIRNVKGPVREGDVLTLLESEREARRLR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W334-1", "uniprot_id": "RS28_DROME", "id": "Q9W334-1", "name": "Small ribosomal subunit protein eS28", "aln": "MD----KPVVWARVMKVLGRTGSQGQCTQVKVEFLGEQNRQIIRNVKGPVREGDILTLLESEREARRLR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAB9-1", "uniprot_id": "Q9VAB9_DROME", "id": "Q9VAB9-1", "name": "Small ribosomal subunit protein eS28", "aln": "MD----KPQ-YARVVEILGRTGSQGQCTQVRVEFLGDQSRQIIRNVKGPVRVGDILSLLETEREARRLR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3E7X9-1", "uniprot_id": "RS28A_YEAST", "id": "Q3E7X9-1", "name": "Small ribosomal subunit protein eS28A", "aln": "MDN--KTPVTLAKVIKVLGRTGSRGGVTQVRVEFLEDTSRTIVRNVKGPVRENDILVLMESEREARRLR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0C0X0-1", "uniprot_id": "RS28B_YEAST", "id": "P0C0X0-1", "name": "Small ribosomal subunit protein eS28B", "aln": "MDS--KTPVTLAKVIKVLGRTGSRGGVTQVRVEFLEDTSRTIVRNVKGPVRENDILVLMESEREARRLR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * *:* ::******:* ***:***: : .* *:******** .*:* *:*:********", "identical_positions": 40, "similar_positions": 13, "identity": "57.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2025", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0CX44-1", "uniprot_id": "RL1B_YEAST", "id": "P0CX44-1", "name": "Large ribosomal subunit protein uL1B", "aln": "-MSKITSSQVREHVKELLKYSNETKKRNFLETVELQVGLKNYDPQRDKRFSGSLKLPNCPRPNMSICIFGDAFDVDRAKSCGVDAMSVDDLKKLNKNKKLIKKLSKKYNAFIASEVLIKQVPRLLGPQLSKAGKFPTPVSHNDDLYGKVTDVRSTIKFQLKKVLCLAVAVGNVEMEEDVLVNQILMSVNFFVSLLKKNWQNVGSLVVKSSMGPAFRLY", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX43-1", "uniprot_id": "RL1A_YEAST", "id": "P0CX43-1", "name": "Large ribosomal subunit protein uL1A", "aln": "-MSKITSSQVREHVKELLKYSNETKKRNFLETVELQVGLKNYDPQRDKRFSGSLKLPNCPRPNMSICIFGDAFDVDRAKSCGVDAMSVDDLKKLNKNKKLIKKLSKKYNAFIASEVLIKQVPRLLGPQLSKAGKFPTPVSHNDDLYGKVTDVRSTIKFQLKKVLCLAVAVGNVEMEEDVLVNQILMSVNFFVSLLKKNWQNVGSLVVKSSMGPAFRLY", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53026-1", "uniprot_id": "RL10A_MOUSE", "id": "P53026-1", "name": "Large ribosomal subunit protein uL1", "aln": "MSSKVSRDTLYEAVREVLHG-NQRKRRKFLETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCVLGDQQHCDERKAVDIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENMVAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62907-1", "uniprot_id": "RL10A_RAT", "id": "P62907-1", "name": "Large ribosomal subunit protein uL1", "aln": "MSSKVSRDTLYEAVREVLHG-NQRKRRKFLETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCVLGDQQHCDEAKAVDIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENMVAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62906-1", "uniprot_id": "RL10A_HUMAN", "id": "P62906-1", "name": "Large ribosomal subunit protein uL1", "aln": "MSSKVSRDTLYEAVREVLHG-NQRKRRKFLETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCVLGDQQHCDEAKAVDIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENMVAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6A8X9-1", "uniprot_id": "A0A8I6A8X9_RAT", "id": "A0A8I6A8X9-1", "name": "Ribosomal protein", "aln": "MSSKVSHDTLYEAVREVLHG-NQRKRRKFLETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCVLGDQQHCDEAKVVDIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKVGKFPSLMTHNENMVAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTDDKLVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQHLY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZRE5-1", "uniprot_id": "A0A8I5ZRE5_RAT", "id": "A0A8I5ZRE5-1", "name": "Ribosomal protein", "aln": "MSSKVSRDTLYEAVWEVLHG-NQRKRRKFLETVELQISLKNYDPQKEKHFSGTVRLKSTPRPKFSVCVLGDQQHCDEAKAVDIPDMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPRLNKAGKFPSLLTHNENMGAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PC69-1", "uniprot_id": "RL10A_DANRE", "id": "Q6PC69-1", "name": "Large ribosomal subunit protein uL1", "aln": "-MSKVSRDTLYEAVKEVQAG-SRRKKRKFLETVELQISLKNYDPQKDKRFSGTVRLKTTPRPKFSVCVLGDQQHCDEAKAAELPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENLGTKVDEVKSTIKFQMKKVLCLAVAVGHVKMSEEELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTP4-1", "uniprot_id": "R10AB_DROME", "id": "Q9VTP4-1", "name": "Large ribosomal subunit protein uL1", "aln": "MASKVSRDTLYEGVNGLLEA-SAKKKRGFLETVELQIGLKNYDPQKDKRFSGTVKLKHIPRPKMKVCILGDQQHCDEAKANNVDFMDAEALKKLNKNKKLVKKLAKSYDAFLASESLIKQIPRLLGPGLNKAGKFPALLSHQESMIGKIEEVKSTIKFQMKKVLCLSVAVGHVGMKSDELAQNVNLSINFLVSLLKKNWQNVRSLHVKSSMGPPQRLY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFE0-1", "uniprot_id": "Q9VFE0_DROME", "id": "Q9VFE0-1", "name": "Large ribosomal subunit protein uL1", "aln": "MVSKVSRDTIYVAVKNILLN-SQAKGPDCLETVELQIGLRDYDPDKCKRFHGSVLLHHLAVPQLKVCVFGDQEHCYKAKAIGVDCLDVEALKKLNKDPKLTKKLSKAYDVFLASESIIKQIPRLLGPGLTNAGKFLTPLARGESMSSKIK-ILSTKKKHMKRMECLSVNVGHVGMHPEELARNIAISINFLVSLLKDNWQNVRSLHIKSSLGVPHQLY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:: . : * : . * *******:.*::***:: *:* *:: * . *::.:*::** . . * : :. : ******: ** ***:* *:.*:*** :***:**:*** *.:.*** : ::: :.: *: : ** * ::*:: **:* **:* * : *. :: :::**:*****.***** :* :**::* . :**", "identical_positions": 84, "similar_positions": 69, "identity": "38.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2032", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1A6-1", "uniprot_id": "VIGLN_RAT", "id": "Q9Z1A6-1", "name": "Vigilin", "aln": "----------MSSVAVLTQESFAEHRSGLVPQQIIVATLNS----EEESDPPTYKDAFPPLPEKAACLESAQEPAGAWSN-KIRPIKASVITQVFHVPLEERKYKD-------------MNQFGEGEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVPIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPD----------DPSNQIKITGTKEGIEKARHEVLLISAEQDKRAVKRLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSFTVSSVSAPSWLHRFIIGKK---------------GQNLAKITHQMPKVHIEFTEGEDKITLEG---PTEDVNVAQEQIEGMVKDLINRMDYVEINIDHKFHR------HLIGKSGANINRIKDQYKVS---VRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSEIVQLRGPKNE-VEKCTKYMQKMVADLVENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSE------TIVITGKRANCEAARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARIIF------PAAEDKDQDLITIIGKEDAVREAQKELEALIQNLDNVVEDYMLVDPRHHRHFVIRRGQVLREIAEEYGG-----VMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTLECAIPQKFHRSVMGPKGSRIQQITRDYNVQIKFPDREENPVHSVEPSIQENGDEAGEGREAKETDPGSPRRCDIIVISGRKEKCEAAKEALEALVP---VTIEVEVPFDLHRYIIGQKGSGIRKMMDEFEVNIHVPAPELQSHTIAITGLAANLDRAKAGLLDRVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGGKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILKIVGELEQMVSEDVP-----LDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEEEYLADVVDSEALQVYMKPP-----AHEESKAPSKGFVVRDAPWTSNSSEKAPDMSSSEEIPTFGAQVAP--KTLPWGPKR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDJ3-1", "uniprot_id": "VIGLN_MOUSE", "id": "Q8VDJ3-1", "name": "Vigilin", "aln": "----------MSSVAVLTQESFAEHRSGLVPQQIKVATLNS----EEENDPPTYKDAFPPLPEKAACLESAQEPAGAWSN-KIRPIKASVITQVFHVPLEERKYKD-------------MNQFGEGEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVPIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPD----------DPSNQIKITGTKEGIEKARHEVLLISAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSFTVSSVSAPSWLHRFIIGKK---------------GQNLAKITQQMPKVHIEFTEGEDKITLEG---PTEDVNVAQEQIEGMVKDLINRMDYVEINIDHKFHR------HLIGKSGANINRIKDQYKVS---VRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNE-VEKCTKYMQKMVADLVENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSE------TIIITGKRANCEAARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARIIF------PAAEDKDQDLITIIGKEDAVREAQKELEALIQNLENVVEDYMLVDPKHHRHFVIRRGQVLREIAEEYGG-----VMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTVECAIPQKFHRSVMGPKGSRIQQITRDYNVQIKFPDREENPVHSVEPSIQENGDEAGEGREAKETDPGSPRRCDIIIISGRKEKCEAAKEALEALVP---VTIEVEVPFDLHRYIIGQKGSGIRKMMDEFEVNIHVPAPELQSDTIAITGLAANLDRAKAGLLDRVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHEVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILKIVGELEQMVSEDVP-----LDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEEEYLADVVDSEALQVYMKPP-----AHEESRAPSKGFVVRDAPWTSNSSEKAPDMSSSEEFPSFGAQVAP--KTLPWGPKR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00341-1", "uniprot_id": "VIGLN_HUMAN", "id": "Q00341-1", "name": "Vigilin", "aln": "----------MSSVAVLTQESFAEHRSGLVPQQIKVATLNS----EEESDPPTYKDAFPPLPEKAACLESAQEPAGAWGN-KIRPIKASVITQVFHVPLEERKYKD-------------MNQFGEGEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPD----------DPSNQIKITGTKEGIEKARHEVLLISAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSFTVSSVAAPSWLHRFIIGKK---------------GQNLAKITQQMPKVHIEFTEGEDKITLEG---PTEDVNVAQEQIEGMVKDLINRMDYVEINIDHKFHR------HLIGKSGANINRIKDQYKVS---VRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNE-VEKCTKYMQKMVADLVENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSE------TIIITGKRANCEAARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIF------PAAEDKDQDLITIIGKEDAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYGG-----VMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTLECAIPQKFHRSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQENGDEAGEGREAKDCDPGSPRRCDIIIISGRKEKCEAAKEALEALVP---VTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAITGLAANLDRAKAGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQMVSEDVP-----LDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEEEYLADVVDSEALQVYMKPP-----AHEEAKAPSRGFVVRDAPWTASSSEKAPDMSSSEEFPSFGAQVAP--KTLPWGPKR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BDG6-1", "uniprot_id": "A0A8M2BDG6_DANRE", "id": "A0A8M2BDG6-1", "name": "Vigilin", "aln": "----------MSSVAVLTQESFNEHRSGLLPEQVKAAAGGDPSSVEDDDSLPTYKDAFPPLPEKP-LPEGVQETENAWTT-KIKPLKSSIITQVFHVPLEERKYKD-------------MNQFGEGDQAKVCLDIMHKTGAHLELSMAKDQGLSIMVSGKYDAVMKARKEIVSRLQTQASATVAIPKEHHRFVIGKSGEKLQELELKTATKIQIPRPD----------DPSNQIKISGTKEGLEKAKHEILLISAEQDKRAVERMNIDKVFHPFITGAHGKLVGDLMQETGARINVPPPSVNKTEIVITGEKEQVALAMVKIKKLYEEKKKNATTIAVEVKKSQHKYVIGPKGNTLQEILERTGVSVEIPPLDSSSETVILRGEPARLGQALTEVYAKANSYTVSSVSAPSWLHRFIIGKK---------------GQNLAKITQQMPKVHIEFTEGEDKITLEG---PTKDVQIVQGQIEVIVTDLVSRMDYTEISVDPKFHR------HLIGKGGANINRIKELHKVS---VRIPPDNEKSNLIRIEGDPQGVQEAKKELLELASRMENERTKDMIIEQRFHRAIIGQKGEKIKEIRDKFPEVIINFPDPAQKSDIVQLRGPRTE-VEKCSKFMQKMVAEMVENSFSVSVPIFKQFHKNIIGKGGANIKKIREETNTKIDLPAENSNSE------MIVITGKKANCEAAKNRILAIQKELANITEVEVSIPSKLHNSLIGSKGRFVRSIMEECGGVHIHFPTEGSGIDAVTIRGPAEEVEKAKKQLLSLAEEKQTKSHTVELRAKPEYHKFLIGKGGGNIRKVRDSTGARIIF------PTAEDKDHELITVIGTEEAVAEAQKELEALIKSLDNIVEDFMIVDPKHHRFFVARRGQVLRDIADEYGG-----VIVSFPRTAAQSDKVTLKGAKDCVEAAKKRMLEMIEDLDAQVTMECVIPQKFHRSIMGPKGSRIQQITKDHNVQIKFPDREEQ--QQADASVQENGEANGEVKEP--VDPTAPKKCDVIVLSGRKERCEAAVEALKALVP---VTIAVEVPFELHRYIIGQKGSGIRKMMDEFEVNIQVPAHELQSDIISITGLASHLDRAKEGLLERVKELQAEQEDRALRSFKLTITVEPKYHPKIIGRKGAIISHIRHDHEVNIQFPEKNDENQ--DQITITGYEQNAIAARDAIQAIVDELEEMISEDIT-----LDSRVHARIIGARGKGIRKIMDEFKVDVRFPQSGAADPNLVTVTGRPEHVDEAIDHLLNLEEEYMADVVENEAKMAYMKPSGSSASSMEEPRGPSKGFVVREAPWATGN-EKAPDMSSSEEFPSFGAPVAAAARASPWGPKRF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1LYH5-1", "uniprot_id": "F1LYH5_RAT", "id": "F1LYH5-1", "name": "Vigilin", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSKRQYIVYPNRSLQRESHVTNLNSRKVNFPSSSCNSE------NNISIRKPENREICHNWILSIPKNAAKDSEVEIPIPPSLHRSLTDSKKSLIGSIIEECGKVQIHFPSNNQGPQKVIISGTTDIVEKAKKRLLQLAEEEQAKSYSVAIPVKSKYHQFLMSKNGGNLQSICEKTGVRIIF------PTFKNKDQESITIIGTEEAVKNVKKVVEVLLKDLEDVVEDNILISPKFHNYFVMQRGQLLREIIKEYGG-----VFVTFSYAGKQSTKVTIKGAKACVEAAKKHIQGIFDPLGSQVTAQCVVPPKFHPFIMGPICSRIQQTARECKVQIKFPDTEKT-TKKTHPEVQEMEKDKG-GKNVRKPASTSPKKSDTTSTSGKTENCKEAAQALETLVP---VTAEVQVPFHLHPYIIGHRGSGLRKLIKDFEVHIQVSQPGGNFHIISIMGLEANVEQAKTKLQNQVKALQMELDDQTLRSFRQTFRLDSKYHSKIFGNKGILISQICTEYDVTVHFSKKG-SNSTQDQITISGSKSNILGARDAIMNMLRKIEKTVSREIP-----LNHHVCANIIGFGGKSIQKIMEQYHVDIRVPPKGSHTNSTIIVSGSSANVQEAIDYILSLEKHFLSVGK-SDPPSDHHKRGG----VCNTAARTYKSFGKRNTLRNVKSTTHPPHLDNAEDFPKLKQQTPP--KFHPWRP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A4T3-1", "uniprot_id": "D4A4T3_RAT", "id": "D4A4T3-1", "name": "Vigilin", "aln": "---------------------MNSKRNSASYQNMSVQKENHYKSSNDVVHMSRYNKEVTEHPKKINFSENPEETAESSSINIFKAGEISTLTQVFHVLLEKENY---------------LTQFGEGTLAKFYAHIMENTGVNLESSFIKDQGLYVTVFGNSEAVTNAENEILKWCQEKYLPLTLISKQEHCFFLDQTGDKSQDTEQEAEINAQIISPH----------NHSHYINTVDTNLTKMKSSDGSLSTSDRNSKSDIQILEMEKAFNPRIGKPYLQAS-DIFQETEEHVPFQLSSANETDVDINERQLNVDQTRCHKNDMTE---KSSTITEGMMMKFQGNYTRSLKRNFLEEILETSEDSTGQSPSESISDSMTQHSEPDSSGEIFNEVHGNDDDYIVSSIFAPSWLHRFIIGKK---------------GEKIAEISECVPKVQIHFT-AKDKITLKG---PIDDVNYAQEKFDIIVKDLISRMEYTEINGDSKFHK------YLTGNNGAILNKIAERNQVS---ITMVPENELNHTIRIEGESLGVQQAKKELLDLANNLEEEYSQDIIIKHQFHHILIGQKGERVREICKKFPDVILNFPHPAEKSDIVQLIGPRYE-SEKCAQYLENMLTDIKENNYSISISIIKKLHKRLIGKGASNIKKISETTNTKISFPPENCNSE------EFIITGYPENCEIARNWILSIQQEIADTAEEEITIPTNLYKYLNNPKECLLNSIIEECGKIHLHFPKNKSSLNKVIIMGSVESVEKAKAKLLKLAEEEQAKNYSEKIRVKSQYHQFLVNKNGGNISQICDETGTCVLF------PNHTNKDQESLTITGSEESVKEVQKRLEDLVKDFENEVDDSILINRRFHHYFVMRRGQLLKEMTEEYGG-----VVITFSYAGRQNTKVTIKGAKPCVEAAKKHIKAIFEPLGSQVTTRYVIPQNFQPFIMGPITSRIQQIARDYKVEIKFPDIEKP-AINMDLATQEKGKEKW-KKPAKDLAPNSPRKSDTIFISGQVENCKAATEALASIIP---VTAEVHVPLHLHPYIIGHKGSGLRKLVKEFEVHMQPPQPGKNSDIISIMGLAANVEQAKMKLQKRVKALQMEIEDRTLRNFKLMFNLDSKYRAKITGHKGLLITQICTEHDVTVRFPKKG-SHEVQDQITITGYKENTLAARDAIMRVLHKIEKTISKEIT-----LNQQVRSNVFGFRGKTINKIMDQYQVDIRSPPKGSYN-PNITVTGLPDNVEKAIEHILNLEKYYLSAAANHESQQEEAKSMS----LCNIAMTPSKSFVRKYVPCYAKTTTKLPDVDNCEHFPRLKQRISS--KTHPSKL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06105-1", "uniprot_id": "SC160_YEAST", "id": "P06105-1", "name": "Protein SCP160", "aln": "MSEEQTAIDSPPSTVEGSVETVTTIDSPSTTASTIAATAEEHPQLEKKPTPLPSLKDLPSLGSNAAFANVKVSWGPNMKPAVSNSPSPSPSAPSLTTGLGAKRMRSKNIQEAFTLDLQSQLSITKPELSRIVQSVKKNHDVSVESTLSKN-ARTFLVSGVAANVHEAKRELVKKLTKPINAVIEVPSKCKASIIGSGGRTIREISDAYEVKINVSKEVNENSYDEDMDDTTSNVSLFGDFESVNLAKAKILAIVKEETKNATIKLVVEDEKY----LPYIDVSEFASDEGDEEVKVQFYKKSGDIVILGPRE----KAKATKTSIQDYLKKLASNLDEEKVKIPSKFQFLIDAEELKEKYN----VIVTFPSTPDDELVSFVGLRDKVGEAITYARSSSKSYVVESLDISKAHSKNLTHAKNLIMYFTKYSVLKGLEESHPNVKISLPSIQSLPTAETVTIHISAKSDEANDIKAVRKELISFVNNIPPSETLVITDLDYELFGGSIKHCLLASESSVAFVQFGDYYPNDNSILLVALTEDEDFKPSIEEIQASLNKANESLNSLRTKQNNMETKTYEFSEEVQDSLFKPSSATWKLIMEDISEQEGHLQIKLHTPEENQLTVRGDEKAAKAANKIFESILNSPSSKSKMTVNIPANSVARLIGNKGSNLQQIREKFACQIDIPNEENNNASKDKTVEVTLTGLEYNLTHAKKYLAAEAKKWADIITKELIVPVKFHGSLIGPHGTYRNRLQEKYN-VFINFPRDN---EIVTIRGPSRGVNKAHEELKALLDFEMENGHKMVINVPAEHVPRIIGKNGDNINDIRAEYGVEMDFLQKSTDPKAQETGEVELEITGSRQNIKDAAKRVESIVAEASDFVTEVLKIDHKYHKSIVGSGGHILREIISKAGGEEIRNKSVDIPNADSENKDITVQGPQKFVKKVVEEINKIVKDAENSVTKTIDIPAERKGALIGPGGIVRRQLESEFNINLFVPNKDDP--------------------------------SGKITITGAPENVEKAEKKILNEIIRENFDREVDVPASIYEYVS-ERGAFIQKLRMDLSVNVRFGNTSKKANKLARAPIEIPLEKVCG-------------STEGENAEKTKFTIEEVGAPTSSEEGDITMRLTYEPIDLSSILSDGEEKEVTKDTSNDSAKKEEALDT--AVKLIKERIAKAPSATYAGYVWGADTRRFNMIVGPGGSNIKKIREAADVIINVPRKSDKVNDVVYIRGTKAGVEKAGEMVLKSLRR--------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. . .:: : ::.:* .. *. * .:. : : :. *. *: :* .:: * ..: : *: . : ::** : : * * *. *:**: .* * : : :... : . .:: ::.*.*.:: .: . *. : * * :... : : *..: : :. * :* :: . .: * : : :. :.*. :* *::*::: .: ** : :. : :. .:*::*.: *: . :.: :.. .** :* : : ::** :* : .::: .*: :. .. :* *. : * : : : . *.** :: *: .:*: ::*: ::.*::: : . :: : :::. . . . : . :: .. . : ::. :.. . * . :. :.: : *: : .: : * . : : :.* *. *.** : .* :. * .. : : * *::* : :*. . ", "identical_positions": 67, "similar_positions": 220, "identity": "4.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2035", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1B0GVM2-1", "uniprot_id": "A0A1B0GVM2_HUMAN", "id": "A0A1B0GVM2-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------XYGEDVRQDQQQLLEGISELDIR-TGGVPSQLLVHGALAFPLGLDAS-LNCFLAAAHYGRGRVVLAAHECLLCAPKMGPFLLNAVRWLARGQTGKVGVNTNLKDLCPLLSEHGLQCSLEPHLNSDLCVYCCKAYSDKEAKQLQEFVAEGGGLLIGGQAWWWASQNPGHCPLAGFPGNIILNCFGLSILPQTLKAGCFPVPTPEM---RSYHFRKALSQFQAILNHEN--GNLEKSCLAKLRVDGAAFLQIPAEGVPAYISLHRLLRKMLRGSGLPAVSRENPVASDSYEAAVLSLATGLAHSGTDCSQLAQGLGTWTCSSSLYPSKHPITVEINGINPGNNDCWVSTGLYLLEGQNAEVSLSEAAASAGLRVQIGCHTDDLTKARKLSRAPVVTHQCWMDRTERSVSCLWGGLLYVIVPKGSQLGPVPVTIRGAVPAPYYKLGKTSLEEWKRQMQENLAPWGELATDNIILTVPTTNLQALKDPEPVLRLWDEMMQAVARLAAEPFPFRRPERIVADVQISAGWMHSGYPIMCHLESVKEIINEMDMRSRGVWGPIHELGHNQQWHGWEFPPHTTEATCNLWSVYVHETVLGIPRAQAHEALSPPERERRIKAHLGKGAPLCDWNVWTALETYLQLQQAFGWEPFTQLFAEYQTLSHLP---KDNTGRMNLWVKKFSEKVKKNLVPFFEAWGWPIQKEVADSLASLPEWQENPMQVYLRARK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NFQ2-1", "uniprot_id": "TCAF2_HUMAN", "id": "A6NFQ2-1", "name": "TRPM8 channel-associated factor 2", "aln": "------------------------------------------------------------------------------------------MATIAAAAFEALMDGVTCWDVPRGPIPSELLLIGEAAFPVMVNDKGQVLIAASSYGRGRLVVVSHEGYLSHTGLAPFLLNAVSWLCPCPGAP--VGVHPSLAPLVNILQDAGLEAQVKPEPGEPLGVYCINAYN-DTLTATLIQFVKHGGGLLIGGQAWYWASQHGPDKVLSRFPGNKVTSVAGVYFTDTYGDRDRFKVSKKVPKIPLHVRYGEDVRQDQQQLLEGISELDIR-TGGVPSQLLVHGALAFPLGLDAS-LNCFLAAAHYGRGRVVLAAHECLLCAPKMGPFLLNAVRWLARGQTGKVGVNTNLKDLCPLLSEHGLQCSLEPHLNSDLCVYCCKAYSDKEAKQLQEFVAEGGGLLIGGQAWWWASQNPGHCPLAGFPGNIILNCFGLSILPQTLKAGCFPVPTPEM---RSYHFRKALSQFQAILNHEN--GNLEKSCLAKLRVDGAAFLQIPAEGVPAYISLHRLLRKMLRGSGLPAVSRENPVASDSYEAAVLSLATGLAHSGTDCSQLAQGLGTWTCSSSLYPSKHPITVEINGINPGNNDCWVSTGLYLLEGQNAEVSLSEAAASAGLRVQIGCHTDDLTKARKLSRAPVVTHQCWMDRTERSVSCLWGGLLYVIVPKGSQLGPVPVTIRGAVPAPYYKLGKTSLEEWKRQMQENLAPWGELATDNIILTVPTTNLQALKDPEPVLRLWDEMMQAVARLAAEPFPFRRPERIVADVQISAGWMHSGYPIMCHLESVKEIINEMDMRSRGVWGPIHELGHNQQRHGWEFPPHTTEATCNLWSVYVHETVLGIPRAQAHEALSPPERERRIKAHLGKGAPLCDWNVWTALETYLQLQEAFGWEPFTQLFAEYQTLSHLP---KDNTGRMNLWVKKFSEKVKKNLVPFFEAWGWPIQKEVADSLASLPEWQENPMQVYLRARK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0RBL7-1", "uniprot_id": "M0RBL7_RAT", "id": "M0RBL7-1", "name": "", "aln": "------------------------------------------------------------------------------------------MATTPDAAFEALMNGVTSWDLPKEFTPSELLLIGEAAFPVMVNDKGQVLIAASFYGQGRLVVLSHEGYLLHAGLAPFLLNAVSWLCPSPEAP--IAVHSSLASLVNILRDSGVNALVQPEPGEALGVFCIDAYN-DTLTEKLVQFVKHGGGLLIGGQACNWASQQGSDKVLFSFPGNQVTSVAGVYFTDVYGGINRFKVSKKVPKIPLHIRCWEELRRDQEQLLDGISMLDIR-TGGVPSQLLVHGSLAFPVGLDNSFLSCFLAAARYGCGRVVLAAHEAMLCAPKMEPFLLNAIRWLSRDQGKTIGVNKSLKNLNSLLLKHGVKCSLESHLTSDMGVYCCVAYSDQDAKKIQEFVAEGGGLLIGGQSWWWASQNQGSSALRSFPGNVVLNPFGLSILPQTISPGCFPVLPIDI---RNYHFRRALSEFQAMVNHKG--GNLEKKYFGKLGVDGAGFLQIPAKGVPAYISVHRILRKMLRQAGLPAVSKNNPVSSQSCEAALLCLATELAHSGTDCSQIAHNHGTQTCSSDLCSSEHPITVEINGTNTGDSDVWMSTGLYLLEGQSTEISLSEPAASAGLKVQIGCHTDNLSHARQLFRAPVVTYQCCMDRTQRSVSCLWGGLLYIIVPKGCQLGPVSVTITKAVPAPYYKLGKTSLEEWKSCMQKNLGPWGELATDSVILTVPTESLKNLEDPAPLLQLWDEIMKAVAKLAAQPFPFERPERIVTDVQISNGWMHSGYPIMCHVESVQELVSLADIRSKGLWGPIHELGHNQQRSGWEFRPHTTEATCNLWSVYVHETVLGIPRAQAHPQLKPEEREKRIKEHLQKGAPLSDWKVWTALETYLQLQEVFGWEPFMNLFAEYQCIVHIP---KDNESKMNLWLKLFSEKVQKNLVPFFEAWGWPIQKPVAEALACFPSWQDHPLKMYIGME-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q921K8-1", "uniprot_id": "TCAF2_MOUSE", "id": "Q921K8-1", "name": "TRPM8 channel-associated factor 2", "aln": "------------------------------------------------------------------------------------------MATTPDAAFEALMNGVTSWDLPKEFTPSELLLIGEAAFPVMVNDKGQVLIAVSFYGQGRLVVVSHESYLMHAGLAPFLLNAVSWLCPSPGTP--IEVHSSLASLVNILRGSGINALVQPEPGEALGVYCIDAYN-DTLTKKLVQFVKRGGGLLIGGQAWNWASQHGSDKVLFSFPGNKVTSVAGVYFTDVYGDINRFKVSKKIPKIPLYIRCWEELRHDQDQLLDGISMLDVR-TGGVPSQLLVHGSLAFPLGLDNSFLSCFLAAAHYGRGRVVLAAHEAMLCAPKMEPFLLNAIRWLSRGQEDNIGVNTRLKNLNSLLLKHGLKCSLESHLTDDMCVYCCAAYSDQEAKKIQEFVAEGGGLLIGGQSWWWASQNPGSSALGSFPGNVILNTFGLSILPRTVSPGCFPILHIDI---RNYHFRGALSEFQAMLNHKE--GNLEKRYSGKLGVDGAGFLQIPAQGVPAYLSVHRILRKILRQAGLPAVSKSNPVSSHSYEAAILQLATELAHSGSDCSQIAHNLSSQTCSSNLSSSEHPITVEINGTNPGDRDVWMSTGLYLLEGQSTEISVSEPAASAGLKVQIGCHTDDLTFAIKLFRAPVVTYQCCMNRTQRSVSCLWGGLLYIIVPKGCQLGPVSVTITNAVPAPYYKLGKTSLEEWKSCIQKNLGPWGELATDNVILTVPTASLKTLENPEPLLQLWDEMMQAVARLASQPFPFQRPERIVADVQLSAGWMHSGYPIMCHMESVQELVSLANIRSKGLWGPIHELGHNQQCRGWEFPPHTTEATCNLWSVYVHETVLGIPRAQAHPQLKPEEREKRIKEHLQKGAPLQNWNVWTALETYLQLQEVFGWEPFITLFAEYQTIFYIP---EDNECKMNIWLKLFSEKVQKNLVPFFEAWGWPIQKDVAEDLACYPSWEDHPLRMYMGSE-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z8A4-1", "uniprot_id": "D3Z8A4_RAT", "id": "D3Z8A4-1", "name": "", "aln": "MLSLLSPPPATQRSSFTCQAPPLGLLLWPGGSGEETAWEPLLSSRSDLLPVKLQAFGGCSGAPWCSTEKPLFSPPGAVLEAPRQLPGTNRTMATPSATFEALMNGVTSWDIPDDSVPCELLLIGEASFPIMVNDVGQVLIAASSYGRGRMVVASHEDFLVESQLFVFLVNAVGWLRSSSEST--IGVHSSLAPLVKILESCGIESKIEPEVNDSLGVYCIDAYN-ETMTDKLLQFVKRGGGLLIGGQAWDWDNLGEDDRVLFSFPGNLVTSVAGVYFTDNKADTNCYKVSKKMPKIPILVRCEDDLSEDRDELLHGISDLDITNSDCFPSQLLVHGSLAFPLGLDTH-HGCVIAAARYGRGRVVVTGHKVLFTVGKLGPFLLNAVRWLDGGRRGKIVVQTELRTLSGLLAVGGIDTSIEPQLTSDASVYCFEPTSDVGVKELQEFVAEGGGLFVGTQAWWWAFKNPGVSPLARFPGNLLLNAFGISITSQSLNPGPFHIPKAGT---RTYHFRSTLAEFQVIMGRKR--GNVEKGWLAKLGPDGAAFLQIPAEEIPAYMSVHRLLRKLLSRYRLPVATRENPVINDCCRGAMLSLATGLAHSGSDLSLLIPEIEDVYSSCYLRPSESPITVDVNCTNPGTRYCWMSTGLYIPGRQVIDVSLPEDAASADLKIQIGCHTDDLTRASKLFRGPLVINRCCLDKPMKSINCLWGGLLYIIVPQNSKLGTVPLTVKGAVRAPFYKLGETSKEEWKRRLLEYPGPWGELATDNLILTVPTANLRTLENPEPLLRLWDEVMQAVAKLGGEPFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQELISEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRSRANIALWPPVREKRVRMYLSKGPNVKNWNAWTALETYLQLQEAFGWEPFIRLFTEYRNQTTNS--PTDNVNKMNLWVKMFSQQVQKNLAPFFEAWAWPIQKEVATSLAYLPEWKENIMKLYLLTQL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BNE1-1", "uniprot_id": "TCAF1_MOUSE", "id": "Q8BNE1-1", "name": "TRPM8 channel-associated factor 1", "aln": "-------------------------------------------------------------------------------------------MATPSAAFEALMNGVTSWDIPEDSVPCELLLIGEASFPIMVNDVGQVLVAASSYGRGRMVVASHEDFLLESQLFVFLVNAVGWLRSSPNSA--IGVHSSLAPLVKILESCGIESKIEPEVNDSLGVYCIDAYN-ETMTDKLVQFVKRGGGLLIGGEAWDWDTQGDDDRVLFAFPGNLVTSVAGVYFTDNKADTSFFKVSKKMPKIPILVRCDDDLSDDRDELLRGIIDLDITNSDCFPSQLLVHGSLAFPLGLDTY-HGCVIAAARYGRGRVVVTGHKVLFTVGKLGPFLLNAVRWLDGGRKGKIVVQTELRTLSGLLAVGGIDTSIEPHLTSDASVYCFEPTSDVGVKELQEFVAEGGGLFVGTQAWWWAFKNPGVSPLARFPGNLLLNAFGISITSQSLNPGPFRTPKIGT---RTYHFRSTLAEFQVIMGRKR--GNVEKGWLAKLGPDGATFLQIPAEEIPAYMSVHRLLRKLLSRYRLPVATRENPVINDCCRGAMLSLATGLAHSGSDLSLLIPEIEDVYSSRYLRPSASPITVNVNCTNPGTRYCWMSTGLYIPGRQVIDVSVPESAASADLKIQIGCHTDDLTRASKLFRGPLVINRCCLDKPTKSITCLWGGLLYIIVPQNSKLGSVPLTVKGAVRAPFYKLGETSKEEWKRRLLEYPGPWGELATDNIILTVPTANLRTLENPEPLLRLWDEMMQAVAKLGGETFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQELINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRSRANIALWPPVREKRVRIYLSKGPSVKHWNAWTALETYLQLQEAFGWEPFIRLFTEYRNQTTSSSPPSDNVDKMNLWVKMFSQQVQRNLAPFFEAWGWPIQKEVATSLAYLPEWKENIMKLYLLTQMPH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y4C2-1", "uniprot_id": "TCAF1_HUMAN", "id": "Q9Y4C2-1", "name": "TRPM8 channel-associated factor 1", "aln": "-------------------------------------------------------------------------------------------MATPSAAFEALMNGVTSWDVPEDAVPCELLLIGEASFPVMVNDMGQVLIAASSYGRGRLVVVSHEDYLVEAQLTPFLLNAVGWLCSSPGAP--IGVHPSLAPLAKILEGSGVDAKVEPEVKDSLGVYCIDAYN-ETMTEKLVKFMKCGGGLLIGGQAWDWANQGEDERVLFTFPGNLVTSVAGIYFTDNKGDTSFFKVSKKMPKIPVLVSCEDDLSDDREELLHGISELDISNSDCFPSQLLVHGALAFPLGLDSY-HGCVIAAARYGRGRVVVTGHKVLFTVGKLGPFLLNAVRWLDGGRRGKVVVQTELRTLSGLLAVGGIDTSIEPNLTSDASVYCFEPVSEVGVKELQEFVAEGGGLFVGAQAWWWAFKNPGVSPLARFPGNLLLNPFGISITSQSLNPGPFRTPKAGI---RTYHFRSTLAEFQVIMGRKR--GNVEKGWLAKLGPDGAAFLQIPAEEIPAYMSVHRLLRKLLSRYRLPVATRENPVINDCCRGAMLSLATGLAHSGSDLSLLVPEIEDMYSSPYLRPSESPITVEVNCTNPGTRYCWMSTGLYIPGRQIIEVSLPEAAASADLKIQIGCHTDDLTRASKLFRGPLVINRCCLDKPTKSITCLWGGLLYIIVPQNSKLGSVPVTVKGAVHAPYYKLGETTLEEWKRRIQENPGPWGELATDNIILTVPTANLRTLENPEPLLRLWDEVMQAVARLGAEPFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQELINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRSRANIALWPPVREKRVRIYLSKGPNVKNWNAWTALETYLQLQEAFGWEPFIRLFTEYRNQTNLP---TENVDKMNLWVKMFSHQVQKNLAPFFEAWAWPIQKEVATSLAYLPEWKENIMKLYLLTQMPH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P6V7-1", "uniprot_id": "TCAF3_RAT", "id": "Q6P6V7-1", "name": "TRPM8 channel-associated factor 3", "aln": "------------------------------------------------------------------------------------------MATTPDAAFEALMNGVTSWNLPKEPTPSELLLTGEAAFPVMVNDKDQVLIAASFYGHGRLVVLSHESYLLHAGLAPFLLNAVSWLCPSPEAP--IAVHSSLASLVKILGDSGVNAVVQPEPREALGVYCIDAYS-ETLTETLIRFMKNGGGLLIGGQALTWAVHHGHEKVLSSFPGNQVTSVAGVYFTDISGNRDWFKVSKEIPNLTLYVQCEDELKYDQQQLLKGMSEMDIE-TGPVPSQLLVHGQRAFPLGVDNS-FNCFLAAARFGRGRVVLAGHESLILNQTMLPFVLNALRWLMGNQTGRIGLASEMKALKSVLPNSSFEWSETELLTNDLSVFCSCSLGKTDPKKVEEFVAEGGGLLIGAEAWMWGRRNPDSNCMTQYPNNIILKRFGVGIISQVVQRGRFPVPNPEV---INYHIRRALSQYESVIHSQG--SSLQEGWLNKLSQDCFYMFQMTHQRISIYDSVKEHALKMIQSQGFPSVTEQHPITKGSSQAFLLSLAYELFKSGVDRSQLLP------PPTLLSPTESPMTIKIS---TGNDNSWVSTGLYLPEGQVAQVTLPTEATHAKLKVLIGCHIDNISQAKTYIRPPVMTYVYHLTSSQTSISWLYGGLLYIMVPDKYNQDNVSVTISGAVSAPYFRLGKTTQEEWKNLIEHSKAPWGELATDNIILTIPTVNLKVLQDPYPLLQLWDKIVKAVAKLAARPFPFQRPERIVLDKQISFGFLHSGYPIMGLIIIVEGIINEFKIRSHGVWGVTHELGHNHQKPGWTFRPHTTEALCNLWSIYVHETVLNIPRDQAHPSLNPELRKQRIKDHLNKGAPLSNWIVWTALETYLQLQEGFGWEPFIQLFANYQTLTGLP---QNNEDKMNLWVKKFSEVVQKNLAPFFKAWGWPVQHAVAKSLASLPEWQENPMKMYTAESTEHTE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6QR59-1", "uniprot_id": "TCAF3_MOUSE", "id": "Q6QR59-1", "name": "TRPM8 channel-associated factor 3", "aln": "------------------------------------------------------------------------------------------MATTPDAAFETLMNGVTSWDLPKEPIPSELLLTGESAFPVMVNDKGQVLIAASSYGQGRLVVVSHESYLLHDGLVPFLLNVVKWLCPCPGAP--IAVHSSLASLVNILGDSGINALVQPEPGEALGVYCIDAYN-DALTEKLIQFLKNGGGLLIGGQALNWAAHHGHDKVLSIFPGNQVTSVAGVYFTDISANRDWFKVSKEIPNLRLYVQCEDELEDDQQQLLKGMSEIYIE-AGVIPSQLLVHGQRAFPLGVDNS-LNCFLAAARYGRGRVVLGGNESLILNQTMLPFVLNALHWLMGNQTGRIGLASDMKVLKSMLPNSSFQWSESELLTSDLSVFCCCSLANIDSEEVEEFVAEGGGLLIGAEAWSWGRRNPYSSCMTQYPDNIVLKRFGLGITSHVAQRGSFPFPNPEG---TNYHFRRALSQFESVIYSRG--SSLHESWLNKLSQDCFYMFQMTHQRISIYDSVKKHALKMIQSKDFPSVTEQYPIARGSSQAFLLSLAYELFKSGVDRSQLLP------PPALLPPTESPITIKIS---TDNDNSWVSTGLYLPEGQVAQVLLPSEATHAKLKVLIGCHRDNISQARTYFRPPVMTYVYHLTSSQTSISWLYGGLLYIMVPNKYNQDNVSVTIRGAVSAPYFRLGKTTQEEWKNLITHSKAPWGELATDNIILTIPTVNLKELQDPYPLLQLWDKMVRAVAKLAARPFPFQRAERVVLDKQISFGFLHSGYPIMGLISIVEGIISEFKIRSHGIWGVIHELGHNHQKSGWTFPPHTTEALCNLWTIYVHETVLNIPREQAHPSLNPELRRQRIKYHLNKGAPLSNWIMWTALETYLQLQEGFGWEPFIQVFADYRTLSGLP---QNNEDKMNLWVKKFSEAVHKNLAPFFEAWGWPVKYAVAKSLASLPEWQENPMKRYTAEGTEGRE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A4IG42-1", "uniprot_id": "TCAF_DANRE", "id": "A4IG42-1", "name": "TRPM8 channel-associated factor homolog", "aln": "--------------------------------------------------------------------------------------------MAREQDYYTLMSGMQQLDLQGKAVPSDLVLIGEHAFPLAMNPRGQVLMAASHYGRGRIVVLGHEEYLTR--FPGLIENAIMWLMPCTGDAGVVGIQKSLRTVAENLNYSPFKTELG-DFQDRFAIYITDAYSVESSAKDLIAFLKAGGGLIIAGQAWSWSYEHPQENTIRNFPGNKVCSVAGIYFSELEGEVGTFPVPRNIPSSWLAVAIGKDFKEDLEFLLEGVSEFDTQ-GGAIASEVMVHGPLAFPIAVTPN-GKTFIAGAYYGQGRVIVVSHEGYMGRDSLSSFMINAIKWLDEGRKGVVGIVPNLTAAHTVLSKSGLDCQLTG-FREDLSVYVCTSYSDAQCAEIQEFVAEGGGLLIGGHAWYWAQTHCGSNVMTEYPGNHILNKMGLCLLGNTLGGGLYKAPEIEHSCKHGYHFRSMLQRFAQHVSQGQELTDREQGCLKQLGTDCASYLQMRCHDSAAYTSVVALLSDIVKEVGVPQVCSNCPVESPK-DHLMLHIGTEVYKVTPDPDALLPYIIK-DRPNLPTLSNARVRITAN---TGGCEEWISTGLYLSPGMKTYIAVPPEIVGKNWQVQLGCQTDNIGGSNTLKRAPVVHARFPLDSEMVQVWNLWGGLIYLIAPSQTKVDGVEIVVQNAVQAPYFKSGETSVADWVSHIRQAPAPWAELEFENLIMTFDSAFIRNLDRPDEVAKLWDTIMRTITDLAARPPKLPRKERFVADVQISYGFMHAGYPIMMHSGSAPGLVNVEEAYKCGLWGAIHELGHNQQRGVWEFPPHTTECTCNLWSLYVHEQVFGIKSANAHPAITPADRQARTKMYFDGGKDLNSWCMWMALETYMQLQEKFGWDAFKKVFSLYHDMTGVP---NDNAGKMNLYAQTFSKVVNLNLSPFFKAWGWPIQPNTEQNLSHLPAWSDHPVSQYA--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:. * : ** *: : . ..*:::*** ***:.: .:*.* :* ***:: .:: : .: .*::**::** .: : : : :* ... . : .* *: . .. :::*********::* .:* *. : : :*.* :*: :*: : . * : **:* * .: : . .: :* * :*: . . * *: .:: .* . . *: :* :. : : * . : . : : : . .. *:*****: : :. . :: :**: *:: : * *:: : .: *:***:*::.*. : . * :.: ** **::: *:*: :* : . .**.** :.:*:*. : :: *. * : :*** :::::: *.... : :*.* * *:* *::*:***** . ::. . *:** ****:*:* * * *****. **** :**** *:.* .*: : * *. * : :: * : * * *****:***: ***:.* :*: *: . :* :**:: : **. *: ** ***:**.**:: . *: * *.:: : * ", "identical_positions": 170, "similar_positions": 213, "identity": "16.57%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-204", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q16594-1", "uniprot_id": "TAF9_HUMAN", "id": "Q16594-1", "name": "Transcription initiation factor TFIID subunit 9", "aln": "MESGKTASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKATVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRYCLTAPNYRLKSLQKKASTSAGRITVPRLSVGSVTSRPSTPTLGTPTPQTMSVSTKVGTPMSLTGQRFTVQMPTSQSPAVKASIPATSAVQNVLINPSLIGSKNILITTNMMSSQNTANESSNALKRKREDDDDDDDDDDDYDNL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QDT4-1", "uniprot_id": "F1QDT4_DANRE", "id": "F1QDT4-1", "name": "", "aln": "-----MASPKTVPKDAQVMMQILKDMGITEYEPRVVNQMLEFTYRYVTTIIEDAKIYSAHAKKSSVDADDIRLAIQCRVDQSFTSPPPRDFLLDIARQKNQTPLPLIKPYTGPRLPPDRYCLTAPNYRLKSLQKKVSSSAGRITVPRLSVGAVSSRPSTPTLGTPSVQT--VGTKVGTPVSLTGQRFTVQIPSSQTASVKSATPTTPTVQNVLINPSLIGSKNILITTNMVS-QNSSSEST-SLKRKHEDEDD-------YDAL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****::*****:* ***************:******::******::******:****::*****:*******.*******************:***********:************************.*:*************:*:***********: ** *.******:**********:*:**:.:**:: *:*.:**********************:* **::.**: :****:**:** ** *", "identical_positions": 203, "similar_positions": 40, "identity": "76.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2042", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96QK1-1", "uniprot_id": "VPS35_HUMAN", "id": "Q96QK1-1", "name": "Vacuolar protein sorting-associated protein 35", "aln": "-----------------------------------MPTTQQSPQDEQEKLLDEAIQAVKVQSFQMKRCLDKNKLMDALKHASNMLGELRTSMLSPKSYYELYMAISDELHYLEVYLTDEFAKGRKVADLYELVQYAGNIIPRLYLLITVGVVYVKSFPQSRKDILKDLVEMCRGVQHPLRGLFLRNYLLQCTRNILPDEGEPTDEETTGDISDSMDFVLLNFAEMNKLWVRMQHQGHSRDREKRERERQELRILVGTNLVRLSQLEGVNVERYKQIVLTGILEQVVNCRDALAQEYLMECIIQVFPDEFHLQTLNPFLRACAELHQNVNVKNIIIALIDRLALFAHREDGPGIPADIKLFDIFSQQVATVIQSRQDMPSEDVVSLQVSLINLAMKCYPDRVDYVDKVLETTVEIFNKLNLEHIATSSAVSKELTRLLKIPVDTYNNILTVLKLKHFHPLFEYFDYESRKSMSCYVLSNVLDYNTEIVSQDQVDSIMNLVSTLIQDQPDQPVEDPDPEDFADEQSLVGRFIHLLRSEDPDQQYLILNTARKHFGAGGNQRIRFTLPPLVFAAYQLAFRYKENSKVDDKWEKKCQKIFSFAHQTISALIKAELAELPLRLFLQGALAAGEIGFENHETVAYEFMSQAFSLYEDEISDSKAQLAAITLIIGTFERMKCFSEENHEPLRTQCALAASKLLKKPDQGRAVSTCAHLFWSGRNTDKNGEELHGGKRVMECLKKALKIANQCMDPSLQVQLFIEILNRYIYFYEKENDAVTIQVLNQLIQKIREDLPNLESSEETEQINKHFHNTLEHLRLRRESPESEGPIYEGLIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZM34-1", "uniprot_id": "Q6ZM34_DANRE", "id": "Q6ZM34-1", "name": "Vacuolar protein sorting-associated protein 35", "aln": "MCAGSARHEAEQQQSHDTTHSQGGHPVFPLTYLIIMPTTQQSPQDEQEKLLDEAVQAVKVQSFQMKRCLDKNKLMDALKHASNMLGELRTSMLSPKSYYELYMAISDELHYLEVYLTDEFAKGRKVADLYELVQYAGNIIPRLYLLITVGVVYVRSFPQSRKDILKDLVEMCRGVQHPLRGLFLRNYLLQCTRNILPDDGEQAEEEMTGDINDSIDFVLLNFAEMNKLWVRMQHQGHSRDREKREKERQELRILVGTNLVRLSQLEGVNVEKYKQIVLSGVLEQVVNCRDSLAQEYLMECIIQVFPDEFHLQTLNPFLRSCAELHQNVNVKNIIIALIDRLALFAHREDGPGIPAEIKLFDIFSQQVATVIQSRQDMPSEDVVSLQVSLINLAMKCYPDRVDYVDKVLESTVEIFNKLNLEHIATSSAVSKELTRLLKIPVDTYNNILTVLQLKHFPPLFEYFDYESRKSMSCYVLSNILDYNTIIVAQDQVDAILNLVSTLIQDQPDQPAEDPDPEDFAEEQSLVGRFIHLLHSDDPDQQYLILNTARKHFGAGGNQRIRHTLPPLVFAAYQLAFRYKENSSSDDKWEKKCQKIFSFAHQTISALIKAELAELPLRLFLQGALAAGEIGFENHETVAYEFMSQAFSLYEDEISDSKAQLAAITLIIGTFERTRCFSEENHEPLRTQCALAASKLLKKPDQCRAVSICAHLFWSGRNTDKGGDEIRDGRRVMECLKKALKIANQCMDPSLQVQLFIEILNRYICFYERENDAVTVQVLNQLIQKIREDLPNLEASEETEQINKHFHNTLEHLRLQRESPESEGPAYEGLVL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *******************:***************************************************************************************************:*******************************************:** ::** ****.**:******************************:*************************:******:*:*********:****************************:***********************************:*****************************************************:*****************************************:**** *********************:***** **:*****:*:**************.*********:************:*:*************************.********************. **************************************************************************************** :*************************** **** *************.*:*::.*:********************************** ***:******:******************:********************:********* ****:*", "identical_positions": 748, "similar_positions": 38, "identity": "90.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2046", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M6Q7-1", "uniprot_id": "A0ABK0M6Q7_RAT", "id": "A0ABK0M6Q7-1", "name": "", "aln": "--------------------------------------------------------------------------------------MLTPMVAGGVVFPGLFLLSKNTLQRLPQ-------LRWEEADAVIVSARLVSSVQAIMASTAGYIVSTS--CKHIIDDQHWLSSAYTQFAVPYFIYDIYAMFLCHWHKHQVKGHGGEDGTPRALGSTWAVVRGYLHK------------------------------------EFLMVLHHAAMVLVCFP-----LSVVWRQGKGDFFLGCMLMAEVSTPFVCLGKILIQYKQQHTLLHKVNGALMLLSFLCCRVLLFPYLYWAYGRHAGLP-LLSVPMAIPAHVNLGAALLLAPQLYWFFLICRGACRLFR---------------PRGS--PPRSPCQTQD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TNV1-1", "uniprot_id": "TLC3B_MOUSE", "id": "Q7TNV1-1", "name": "Ceramide synthase", "aln": "--------------------------------------------------------------------------------------MLTPMVAGGVVFPGLFLLSKNTLQRLPQ-------LRWEEADAVIVSARLVSSVQAIMASTAGYIVSTS--CKHIIDDQHWLSSAYTQFAVPYFIYDIYAMFLCHWHKHQVKGHGGEDGTPRALGSTWAVVRGYLHK------------------------------------EFLMVLHHAAMVLVCFP-----LSVVWRQGKGDFFLGCMLMAEVSTPFVCLGKILIQYKQQHTLLHKVNGALMLLSFLCCRVLLFPYLYWAYGRHAGLP-LLSVPMAIPAHVNLGAALLLAPQLYWFFLICRGACRLFR---------------PRGS--PPPSPCQTQD----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q71RH2-1", "uniprot_id": "TLC3B_HUMAN", "id": "Q71RH2-1", "name": "Ceramide synthase", "aln": "--------------------------------------------------------------------------------------MLTPMVAGGVVFPGLFLLSKNTLQRLPQ-------LRWEEADAVIVSARLVSSVQAIMASTAGYIVSTS--CKHIIDDQHWLSSAYTQFAVPYFIYDIYAMFLCHWHKHQVKGHGGDDGAARAPGSTWAIARGYLHK------------------------------------EFLMVLHHAAMVLVCFP-----LSVVWRQGKGDFFLGCMLMAEVSTPFVCLGKILIQYKQQHTLLHKVNGALMLLSFLCCRVLLFPYLYWAYGRHAGLP-LLAVPLAIPAHVNLGAALLLAPQLYWFFLICRGACRLFW---------------PRSR--PPP-ACQAQD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BBE5-1", "uniprot_id": "A0A8M2BBE5_DANRE", "id": "A0A8M2BBE5-1", "name": "", "aln": "--------------------------------------------------------------------------------------MLSILAAGSIFFPGLFLLSKRFLKHAPG-------LKWSEKDAVIVSSRLVSSVQAIMASSAGYIIACS--CKDIIEDQHWLTTSYILFAVPYFVYDIYAMFLCYWYKLQVKDHE-EESETKPMRS---AIRGYLHR------------------------------------EFLMVLHHVVMVTVCFP-----VSVFWRQGKGDYFQGVMFLAELSTPSVCLGKILIQYKQQHTLLHKVNGALMLVTFFICRVVLFPYLYYAYGRYASIP-FYMVPLSVPWQCNVGAALLMAPQVYWFSLICRGAFRLFTGASRHKAPISNTDSEPKSSLLPPANGYSPRETDSH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3S7-1", "uniprot_id": "Q9V3S7_DROME", "id": "Q9V3S7-1", "name": "TLC domain-containing protein", "aln": "MQQRRQPANGNGRGGGTTAAVRTEEQQQQQQPLSQDAGAKEAGSTPGKATGRGCYFSLAFSIGSMGLACGSLWQIPNSSDRISLQRGLVLTSLGFIYFVSLTDFCNKYLLETTHGQRFRRKYRLMMSDVLEITNKIVSAIQASFSFFVGLIVCKSTCTKSFVYASHFLMEAYGWFGTAYFMYDIWSMYKVHTQKIADKLHLLRITKGQGAVVSNGHANGKVNGKSASGNNNGSTPTNLHEICDYDGACVQIPKDGRWDFLKYVVTHPVMMIHHVFIGTFGLLVVTYIRGGGHCIYSYMFMMEFSTPFVSLRSILSTMRLKDSRVYIANGLLMLATFFVCRVCMWPYVMWRYSLAIEAASLWSAMWGLPRGCLISIAILFLPQLYWFYLMVLGALKVFLPQKRRP---PNAVLSAKSAAVPTPTPTALINGKN-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : * .* :.:. * . . : *.: :: ::**::** :: .* *:. * * :: .*:* :* *...**:***::*: : * * * : .* :: :* * . *: * : * : :* *. : . *:: *.*** *.* .** : :.: :: .** *** :*: *** ::**: : *. . : . .:* :. *:*: **:*** *: ** ::* .:. *. : ", "identical_positions": 69, "similar_positions": 85, "identity": "15.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2052", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZLT6-1", "uniprot_id": "D3ZLT6_RAT", "id": "D3ZLT6-1", "name": "Kelch-like protein 31", "aln": "MAPKK-KTLKKNKPEINEMTIIVEDSPLNKLNALNGLLGGENSLSCVSSELTDTSYGPNLLEGLSKMRQESFLCDLVIGTKTKSFDVHKSVMASCSEYFYNILKNDPSTKR----VDLNDIAPLGLATVIAYAYTGKLTLSLYTIGSIISAAVYLQIHTLVKMCSDFLIREISVENCMYVVNMAETYCLKNAKATAQKFIRDNFIEFADSEQFMKLTFEQINELLIDDDLQLPSELVAFQIAMKWIEFDQKRVKHAADLLSNIRFGTIS------AQDLVNYVQTVPRMMQDADCHKLLVDAMNYHLLP----YHQNTLQSRRTRIRGGCRVLITVGGRPGLTEKSLSRDVLYRDPENG-WSKLTEMP-AKSFNQCVAVMDGFLYVAGGEDQNDARNQAKHAVSNFCRYDPRFNTWIHLGSMNQKRTHFSLSVFN-GLLYAVGGRNAEGS------LASLECYVPSTNQWQPKAPLEVARCCHASAVADGRVIVTGGYIGSAYSRSVCAYDPALDAWQELPGLSTPRGWHCSVALGDRVYVMGGSQLGPRGERVDVLTVESFSPVARQWSFVAPLPVGVSTAGVSALHGRAYLVGGWNEGEKKYKKCIQCFNPELN---EWMEDD--ELPEATVGVSCCTLAMPNSVSRESRASSVSSVPVSI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BWA5-1", "uniprot_id": "KLH31_MOUSE", "id": "Q8BWA5-1", "name": "Kelch-like protein 31", "aln": "MAPKK-KTIKKNKAEINEMTIIVEDSPLSKLNALNGLLEGSNSLSCVSSELTDTSYGPNLLEGLSKMRQESFLCDLVIGTKTKSFDVHKSVMASCSEYFYNILKNDPSTKR----VDLNDIAPLGLATVIAYAYTGKLTLSLYTIGSIISAAVYLQIHTLVKMCSDFLIREISVENCMYVVNIAETYSLKNAKATAQKFIRDNFIEFAESEQFMKLTFEQINELLVDDDLQLPSELVAFQIAMKWLEFDQKRVKHAADLLSNIRFGTIS------AQDLVNYVQTVPRMMQDADCHKLLVDAMNYHLLP----YHQNTLQSRRTRIRGGCRVLITVGGRPGLTEKSLSRDILYRDPENG-WSKLTEMP-AKSFNQCVAVMDGFLYVAGGEDQNDARNQAKHAVSNFCRYDPRFNTWIHLGSMNQKRTHFSLSVFN-GLLYAVGGRNSEGS------LASLECYVPSTNQWQPKAPLEVARCCHASAVADGRVIVTGGYIGSAYSRSVCAYDPALDAWQELPQLSTPRGWHCAVALGDRLYVMGGSQLGPRGERVDVLTVESFSPAARQWSFVAPLPVGVSTAGVSALHGRAYLLGGWNEGDKKYKKCIQCFNPELN---EWTEDD--ELPEATVGVSCCTLAMPNSVSRESRASSVSSVPVSI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H511-1", "uniprot_id": "KLH31_HUMAN", "id": "Q9H511-1", "name": "Kelch-like protein 31", "aln": "MAPKK-KIVKKNKGDINEMTIIVEDSPLNKLNALNGLLEGGNGLSCISSELTDASYGPNLLEGLSKMRQENFLCDLVIGTKTKSFDVHKSVMASCSEYFYNILKKDPSIQR----VDLNDISPLGLATVIAYAYTGKLTLSLYTIGSIISAAVYLQIHTLVKMCSDFLIREMSVENCMYVVNIAETYSLKNAKAAAQKFIRDNFLEFAESDQFMKLTFEQINELLIDDDLQLPSEIVAFQIAMKWLEFDQKRVKYAADLLSNIRFGTIS------AQDLVNYVQSVPRMMQDADCHRLLVDAMNYHLLP----YHQNTLQSRRTRIRGGCRVLVTVGGRPGLTEKSLSRDILYRDPENG-WSKLTEMP-AKSFNQCVAVMDGFLYVAGGEDQNDARNQAKHAVSNFCRYDPRFNTWIHLASMNQKRTHFSLSVFN-GLVYAAGGRNAEGS------LASLECYVPSTNQWQPKTPLEVARCCHASAVADGRVLVTGGYIANAYSRSVCAYDPASDSWQELPNLSTPRGWHCAVTLSDRVYVMGGSQLGPRGERVDVLTVECYSPATGQWSYAAPLQVGVSTAGVSALHGRAYLVGGWNEGEKKYKKCIQCFSPELN---EWTEDD--ELPEATVGVSCCTLSMPNNVTRESRASSVSSVPVSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6Q7X9-1", "uniprot_id": "KLH31_DANRE", "id": "Q6Q7X9-1", "name": "Kelch-like protein 31", "aln": "MAPKKNKAAKKSKADINEMTIMVEDSPSNKINGLNTLLEGGNGFSCISTEVTDPVYAPNLLEGLGHMRQDSFLCDLTVATKSKSFDVHKVVMASCSEYIQNMLRKDPSLKK----IELSDLSPVGLATVITYAYSGKLTLSLYTIGSTISAALLLQIHTLVKMCSDFLMRETSVENCMYVVNIADTYNLKETKEAAQKFMRENFIEFSEMEQFLKLTYEQINEFLTDDSLQLPSELTAFQIAVKWLDFDEKRLKYAPDLLSNIRFGTIT------PQDLVSHVQNVPRMMQDAECHRLLVDAMNYHLLP----FQQNILQSRRTKVRGGLRVLLTVGGRPALTEKSLSKDILYRDEDNV-WNKLTEMP-AKSFNQCVAVLDGFLYVAGGEDQNDARNQAKHAVSNFSRYDPRFNTWIHLANMIQKRTHFSLNTFN-GLLFAVGGRNSDGC------QASVECYVPSSNQWQMKAPMEVPRCCHASSVIDGKILVSGGYINNAYSRAVCSYDPSTDSWQDKNSLSSPRGWHCSVTVGDRAYVLGGSQLGGRGERVDVLPVECYNPHSGQWSYVAPLLTGVSTAGAATLNNKIYLLGGWNEIEKKYKKCIQVYNPDLN---EWTEDD--ELPEATVGISCCVVTIPTRKTRESRASSVSSAPVSI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRA7-1", "uniprot_id": "Q9VRA7_DROME", "id": "Q9VRA7-1", "name": "Kelch-like protein diablo", "aln": "----------------------MAATPAPAVTPAATATSAAAKIPVNPVSPEEE----TLLRGLNKLRNEEKLTDVTLIVEEHRFKAHRVVLAASSDYFCAMFADCAMIESRKDEINLYGIKARAMGSIIDYIYTSMLELNYDNIEEILAAATHVQVREVIDRCTIFLGAKIEMENCLAIAGMADIYGIMDLSERAYRYMCAHFEEFATTSDFKEMKVDQLRFILSSNYPIDVAEQDLVRLVCSFAIEQQLNESALGDLLRLIKWQHISYKSVDELRNMNCSLDKGKQLPLPTSYYNRIKQEHMGHLLNGVVSLKDQSLPQGPTNMRGMELCLLKIGG---FEWNGLTNVIMCFSPKKMNWYELTAIPHIDQCNFGTAVLNNKLFIVGG--AYDVFLKEYIHPFGFC-YCPLRNTWMTIAPIQQDRCRFSLNAVGTQHLYAVGGILDDDNEEALRMISNVERYDIAKNVWTYMPSLQENRSQHAGVVVGDKLYISGGVHLANILASMWVFDTKTEVWQELASMPTPCCDHVLVAVDNRIYACGGWHESLTEWRVLVEHIYAYDIETNTWSVETKIPAPKFYTGVTAMGRTIFFVGGLDSTESIDRASAETMAYDLDTKEWWHEKDSWDSPNDVWESTCVAIYVPNCDA---------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* :. . :. . . : .**.**.::*::. * *:.: .: : *..*: *:*:.*:*: :: . . : ::* .: . .:.::* * *:. * *. .* . ::** :*:: ::. *: ** : .:***: :..:*: * : : . * ::: :* **: .:* ::. :*:. :* .: :* .::. .: :: . . *** *:: *: ::: ::. :: :. :. : : *** ::: * . *.:** *:.:** : :.*:. :: . .: * :** :* .. * .**::. *::.** *. : .*. * * ***: :. : *.* :***.... ::*.** :. :.:* * :.* * ..:: *. **. * ..:: ::** :: :*. : **: :.:* * *::.:* *. ** : . ** * : .:. : ** : : . :*.::: :::** :. :. : . : :*: * *.* : *: . :* .: :*. : ", "identical_positions": 116, "similar_positions": 234, "identity": "17.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2056", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51797-1", "uniprot_id": "CLCN6_HUMAN", "id": "P51797-1", "name": "H(+)/Cl(-) exchange transporter 6", "aln": "MAGCRGSLCCCCRWCCCCGERETRTPEELTILGETQEEEDEILPRKDYESLDYDRCINDPYLEVLETMDNKKGRRYEAVKWMVVFAIGVCTGLVGLFVDFFVRLFTQLKFGVVQTSVEECSQKGCLALSLLELLGFNLTFVFLASLLVLIEPVAAGSGIPEVKCYLNGVKVPGIVRLRTLLCKVLGVLFSVAGGLFVEKEGPMIHSGSVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWKVLFCSMSATFTLNFFRSGIQFGSWGSFQLPGLLNFGEFKCSDSDKKCHLWTAMDLGFFVVMGVIGGLLGATFNCLNKRLAKYRMRNVHPKPKLVRVLESLLVSLVTTVVVFVASMVLGECRQMSSSSQIGNDSFQLQVTEDVNSSIKTFFCPNDTYNDMATLFFNPQESAILQLFHQDGTFSPVTLALFFVLYFLLACWTYGISVPSGLFVPSLLCGAAFGRLVANVLKSYIGLGHIYSGTFALIGAAAFLGGVVRMTISLTVILIESTNEITYGLPIMVTLMVAKWTGDFFNKGIYDIHVGLRGVPLLEWETEVEMDKLRASDIMEPNLTYVYPHTRIQSLVSILRTTVHHAFPVVTENRGNEKEFMKGNQLISNNIKFKKSSILTRAGEQRKRSQSMKSYPSSELRNMCDEHIASEEPAEKEDLLQQMLERRYTPYPNLYPDQSPSEDWTMEERFRPLTFHGLILRSQLVTLLVRGVCYSESQSSASQPRLSYAEMAEDYPRYPDIHDLDLTLLNPRMIVDVTPYMNPSPFTVSPNTHVSQVFNLFRTMGLRHLPVVNAVGEIVGIITRHNLTYEFLQARLRQHYQTI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F798-1", "uniprot_id": "E7F798_DANRE", "id": "E7F798-1", "name": "Chloride channel protein", "aln": "MACCGGCLCCQC----CCNEGETRTPEELTILGETREDDDEILPRKDYESLDYDRCINEPFLEVLEGLDNKKARKYEAIKWILVFAIGVSTGLTGLFVDFFVRLFTQLKFNVVGQSVEECSENGCLALSLLELLALNMMFVFISSVLVLIEPVAAGSGIPEIKSYLNGVKVPGIVRLRTFICKVTGVLFAVAGGLFVGKEGPMIHSGAIVGAGLPQFQSITFKKIRFHFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQALTWKVLFCSMSATFTLNFFRSGINFSKWGSFQLPGLLNFGEFKCPDGDKACHLWTAVDLAFFVLMGVAGGLLGALFNCINKRLAKYRMRNVHPKARFIRVLESLLVCMVTTLVIFMSSMTLGECRDLVSNVNN-NTSTQGSVNEEVNSTIRRFFCYNNTYNDMATLFFNPQEVAIHQLFHQNATFSPVTLSLFFVLYFFLSCWTYGVSVPSGLFVPSLLCGASLGRLLANVLKINFHM-QIYSGTFALIGAAAFLGGVVRMTISLTVILIESTNEITYGLPIMITLMVAKWTGDFFNRGIYDIHIHLKGVPLLEWETEVEMDKLTASDIMEPNLTYVYPHTRIQSLVSILRTTVYHAFPVVTENRDNEKEFMKGNILISNNIKFKKTSVLTRAGEQRRRCQSMKSYPSSELRNVCDEHVVVEPTEEGQDILQQMLERRHAPYPNLYPDQSPSEEWTMEERFRPLTFHGLILRSQLVNLLIRGVCYAENQSSASQPRLSHSEMTEDYPRFPDIHDLDLALLNPRMIVDVTPYMNPCPYTVSPNTHVSQVFNLFRTMGLRHLPVVNAVGEIVGIITRHNLTHEFLVAKLRQHYITI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * *.*** * **.* **************:*::*******************:*:***** :****.*:***:**::******.***.****************.** ******::***********.:*: ***::*:***************:*.***************::*** ****:******* *********::***********:::**:*:**********************************************.***********************:*..*****************.*.** ******:**.***:*** ****** ***:***************.:::********.:***:*:*::**.*****:: *. : * * * .*.*:***:*: *** *:************** ** *****:.*******:*******:*:*****:***************::***:***** : : :*******************************************:*************:******: *:**************** *****************************:**********.********* **********:*:********:*.*************:****:. * . * :*:********::*************:**********************.**:*****:*.**********::**:*****:********:****************.*:******************************************:*** *:***** **", "identical_positions": 717, "similar_positions": 111, "identity": "82.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2057", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q921I2-1", "uniprot_id": "KLDC4_MOUSE", "id": "Q921I2-1", "name": "Kelch domain-containing protein 4", "aln": "MGKKGKKEKKGRGAEKTAAKMEKKVSKRSRKEEEDLEALIAHFQTLDAKKTQVTETPCPPPSPRLNASLSAHPEKDELILFGGEYFNGQKTFMYNELYIYSIRKDTWTKVDIPGPPPRRCAHQAVVVPQGGGQLWVFGGEFASPDGEQFYHYKDLWVLHLATKTWEQIRSTGGPSGRSGHRMVAWKRQLILFGGFHESARDYIYYSDVYTFSLDTFQWSKLSPSGAGPTPRSGCLMAVTPQG-SIAIYGGYSKQRVKKDVDKGTQHSDMFLLKPAEGGEG--KWAWTRINPSGVKPTARSGFSVAVAPNHQILVFGGVCDEEEEESLEGSFFSDLYIYDAAKSRWFAAQLKGPKSEKKKRRRGKAEDPEGTTEQETGGSSAPEPLEVIKEVVSEDGTVVTIKQVLTPSGLGV----QPSPKADDSASEASSTGQ--EPCPRSNAMLAVKHGLLYVYGGMFEAGDRQVTLSDLYCLDLHKMEEWKTLVEMDPKSQEWLEESDSEEDSSSDEESEDGEDKDQEDSAEEG----ADPQHPEVARGEQFEEYLSRTEQHWLKLARSHVGPEAKEKKVLKVAQAMAKSCFDDAVQDIAQARH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TBB5-1", "uniprot_id": "KLDC4_HUMAN", "id": "Q8TBB5-1", "name": "Kelch domain-containing protein 4", "aln": "MGKKGKKEKKGRGAEKTAAKMEKKVSKRSRKEEEDLEALIAHFQTLDAKRTQTVELPCPPPSPRLNASLSVHPEKDELILFGGEYFNGQKTFLYNELYVYNTRKDTWTKVDIPSPPPRRCAHQAVVVPQGGGQLWVFGGEFASPNGEQFYHYKDLWVLHLATKTWEQVKSTGGPSGRSGHRMVAWKRQLILFGGFHESTRDYIYYNDVYAFNLDTFTWSKLSPSGTGPTPRSGCQMSVTPQG-GIVVYGGYSKQRVKKDVDKGTRHSDMFLLKPEDGRED--KWVWTRMNPSGVKPTPRSGFSVAMAPNHQTLFFGGVCDEEEEESLSGEFFNDLYFYDATRNRWFEGQLKGPKSEKKKRRRGRKEEPEGGSRPACGGAGTQGPVQLVKEVVAEDGTVVTIKQVLTAPGSAG----QPRSEDEDSLEEAGSPAP--GPCPRSNAMLAVKHGVLYVYGGMFEAGDRQVTLSDLHCLDLHRMEAWKALVEMDPETQEWLEETDSEEDSEEVEGAEGG--VDDEDSGEE-----------------------SGAED-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IVV0-1", "uniprot_id": "A0AC58IVV0_DANRE", "id": "A0AC58IVV0-1", "name": "", "aln": "MGKKGKKEKKVKGAEKTAAKMEKKVSKRSKREEEDLEALIAEFQSLDAKKTQVVETACAPPSPRLNASLCAHPEKDELILFGGEFFNGKKTFLYNELYFCNIKKNSWVKADVPNPPPRRCAQQAVVVPQGGGQMWVFGGEFASPDGEQFYHYKDLWVLHLGTRTWEQVKAPGAPSGRSGHRMVLSKRQLLVFGGFHESTRDYIYYNDVHAFNLDTFTWSRLQPTGTGPCPRSACQMTPTSDGNGVIIYGGYSKARAKKDVDKGTIHSDMFLLR-REGKEDQEKWTWTRVNPSGVKPPPRSGFSLAVGPGGRALLFGGVCDEEDEESLEGDFFNDLYFYDMNKNRWFPAQLKGNKSEKKKRRRGKKTEQMNETEEEK--EEAQGPTEIIKEIVAEDGTVMTIKEVIPATQAEEDSEEEEEEEDEEVEEEAAAAAPSVEPCPRSNAMTTVKHGKLFLYGGMFEVGDRQFTLSDLYSLDLHKMEQWDVLVEMDPKTQEWLEESESEDEKEEGDAKGGDDEEDDEDEEESDDESEEDVDHPPVKPGEALTDYQARTEKYWMGLARANMGPDAKEKKVQKVGHAMAKVFFEDQE--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********** :*****************::**********.**:****:**..* .*.**********..*************:***:***:*****. . :*::*.*.*:*.*******:***********:**********:***************.*:****:::.*.********** ****::*******:******.**::*.**** **:*.*:*:** ***.* *: *.:* .: :****** *.******** *******: :* *. **.***:*******..*****:*:.*. : *.********:****.*.**.***:** :.*** .**** **********: : . :. : * :::**:*:*****:***:*:... : : :: .**.:.. ******** :**** *::******.****.*****:.****:** *..******::******::**::... : .. *:**. *. : :*. ", "identical_positions": 333, "similar_positions": 128, "identity": "55.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2063", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LRP2-1", "uniprot_id": "A0ABK0LRP2_RAT", "id": "A0ABK0LRP2-1", "name": "Zinc finger protein 618", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQPDSAAAPQVDGASAPGRKSEVNRELLKHSQKSTKVEGPEPVPAEASLIAEQGTMTEVKVKTEVPDDYIQEVIWQGEAKEEN-AGGQDGTGDVPAEICVVIGGVRNQQTLDGKAPEGSPHGGSVRSRYSGTWIFDQALRYASGSYECGICGKKYKYYNCFQTHVRAHRDTEATS-GEGASQSNN--FRYTCDICGKKYKYYS-------CFQEHRDLHAVDVFSVEGAPENQADPFDQGVVATDEVKEEPPEPFQKIGPKTG-------------NYTCEFCGKQYKYYTPYQEHVALHAPISTAPGWEPPEDPDTGSECSHPEVTPSPRFVAAKTQTNQSGKKAPGSVVRCTTLLHRTPPATQTQTFRTPNSGSPASKATAAENTFSRRVESKAQNHFEETNRSSQNSNETASPLISNPFPLLQKPYTCGACG-------------------IQFQFYSNLLEHMQSHAADNE--NNITSNQSRSPPAAVEEKWKPQAQRNSANN----------------------------------------------------------------------------------------------------------------------------TTTSSLTPNSVIP--------------------------------EKERQNIAERLLRVMCADLGALSVVSGKEFLKLAQTL-----------VDSGARYGAFSVTEILGNFNTLALKHLPRMYNQVKVKVTCA----------LGSNACLGIGVTCHSQSVGPDSCYILTAYQAEG--------NHIKSYVLGVKGADIRDS---------------GDLVHHWVQNVLSEFVMSEIRTVYVTDCRVSTSAFS-KAGMCLRCSACALNSVVQSVLSKRTLQARSMHEVIELLNVCEDLAGSTGLAKETFGSLEETSPP----------PCWNSVTDSLLLVHERYEQICEFYSRAKKMN-LIQSLNKHLLSNLAAILTP------VKQAVIELSNESQPTLQLVLPIYVRLEKLFTAKANDAG---------------------------------TVSKLCHLFLEALKEN--------------------------FKVHPAHKVAMILDPQQKLRPVPPYQHEEIISKVCELINEVKES--------WAEEADFEPSAKKAR---SATGEHPTAQEDDRLGKNEVYDYLQEPLFQATPDLFQYWSCVTQKHTKLAKLAFWLLAVPAVGARSGCVNMCEQALLIK---RRRLLSPE------------DMNKLMFLKSNML--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80YY7-1", "uniprot_id": "ZN618_MOUSE", "id": "Q80YY7-1", "name": "Zinc finger protein 618", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQPDGAAAPQVDGASAPGRKSAVNRERLKRSQKSSKVEGPEPVPAEASLSAEQGTMTEVKVKTEVPDDYIQEVIWQGEAKEEK-AGGKDSTGDVPAEICVVIGGVRNQQTLDGKAPEGSPHGGSVRSRYSGTWIFDQALKYASGSYECGICGKKYKYYNCFQTHVRAHRDTEATS-GEGVSQSNN--FRYTCDICGKKYKYYS-------CFQEHRDLHAVDVFSVEGAPENRADPFDQGVVATDEVKEEPPEPFQKIGPKTG-------------NYTCEFCGKQYKYYTPYQEHVALHAPISTAPGWEPPEDPDTGSECSHPEVTPSPRFVAAKTQSNQSGKKAPASVVRCTSLLHRTPPATQTQTFRAPNSGSPASKAAAAENTFSRRVESKAQNHFEETNSSSQNSSE---------------PYTCGACG-------------------IQFQFYSNLLEHMQSHAADNE--NNITSNQSRSPPAAVEEKWKPQAQRNSANN----------------------------------------------------------------------------------------------------------------------------TTTSGLTPNSVIP--------------------------------EKERQNIAERLLRVMCADLGALSVVSGKEFLKLAQTL-----------VDSGARYGAFSVTEILGNFNTLALKHLPRMYNQVKVKVTCA----------LGSNACLGIGVTCHSQSVGPDSCYILTAYQAEG--------NHIKSYVLGVKGADIRDS---------------GDLVHHWVQNVLSEFVMSEIRTVYVTDCRVSTSAFS-KAGMCLRCSACALNSVVQSVLSKRTLQARSMHEVIELLNVCEDLAGSTGLAKETFGSLEETSPP----------PCWNSVTDSLLLVHERYEQICEFYSRAKKMN-LIQSLNKHLLSNLAAILTP------VKQAVIELSNESQPTLQLVLPTYVRLEKLFTAKANDAG---------------------------------TVSKLCHLFLEALKEN--------------------------FKVHPAHKVAMILDPQQKLRPVPPYQHEEIISKVCELINEVKES--------WAEEADFEPAAKKAR---SATGEHPAAQEEDRLGKNEVYDYLQEPLFQATPDLFQYWSCVTQKHTKLAKLAFWLLAVPAVGARSGCVNMCEQALLIK---RRRLLSPE------------DMNKLMFLKSNML--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T7W0-1", "uniprot_id": "ZN618_HUMAN", "id": "Q5T7W0-1", "name": "Zinc finger protein 618", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNQPGGAAAPQADGASAAGRKSTASRERLKRSQKSTKVEGPEPVPAEASLSAEQGTMTEVKVKTELPDDYIQEVIWQGEAKEEKKAVSKDGTSDVPAEICVVIGGVRNQQTLDGKAPEGSPHGGSVRSRYSGTWIFDQALRYASGSYECGICGKKYKYYNCFQTHVRAHRDTEATS-GEGASQSNN--FRYTCDICGKKYKYYS-------CFQEHRDLHAVDVFSVEGAPENRADPFDQGVVATDEVKEEPPEPFQKIGPKTG-------------NYTCEFCGKQYKYYTPYQEHVALHAPISTAPGWEPPDDPDTGSECSHPEVSPSPRFVAAKTQTNQSGKKAPASVVRCATLLHRTPPATQTQTFRTPNSGSPASKATAAESAFSRRVEGKAQNHFEETNSSSQNSSE---------------PYTCGACG-------------------IQFQFYNNLLEHMQSHAADNE--NNIASNQSRSPPAVVEEKWKPQAQRNSANN----------------------------------------------------------------------------------------------------------------------------TTTSGLTPNSMIP--------------------------------EKERQNIAERLLRVMCADLGALSVVSGKEFLKLAQTL-----------VDSGARYGAFSVTEILGNFNTLALKHLPRMYNQVKVKVTCA----------LGSNACLGIGVTCHSQSVGPDSCYILTAYQAEG--------NHIKSYVLGVKGADIRDS---------------GDLVHHWVQNVLSEFVMSEIRTVYVTDCRVSTSAFS-KAGMCLRCSACALNSVVQSVLSKRTLQARSMHEVIELLNVCEDLAGSTGLAKETFGSLEETSPP----------PCWNSVTDSLLLVHERYEQICEFYSRAKKMN-LIQSLNKHLLSNLAAILTP------VKQAVIELSNESQPTLQLVLPTYVRLEKLFTAKANDAG---------------------------------TVSKLCHLFLEALKEN--------------------------FKVHPAHKVAMILDPQQKLRPVPPYQHEEIIGKVCELINEVKES--------WAEEADFEPAAKKPR---SAAVENPAAQEDDRLGKNEVYDYLQEPLFQATPDLFQYWSCVTQKHTKLAKLAFWLLAVPAVGARSGCVNMCEQALLIK---RRRLLSPE------------DMNKLMFLKSNML--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P963-1", "uniprot_id": "A0A8M1P963_DANRE", "id": "A0A8M1P963-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSCQEVPNPSQEPKDPPVVP---------TEAGATQAVPTTS------PKLPSVTVKTEAP----------AESVASN---GKVSDGSIPAEICVVLGSSRNSQTQG--------------------------------SYICGVCGKKYKYYNCFQTHVRAHSEAEGTVSGEGASLGINSAFRYTCDVCGKKYKYYS-------CFQEHRDLHAVD------------DPYDH-VIPVEDLKEEA-ESFQKMGPKTG-------------SYTCEYCGKQYKYFNPYQEHVALHAPLKGTFGLKLEG-----------------------KLSGQSGQSS------------RVDINNSHNSSDTPNSRTYTSLPSPQK------------------------------------------TYTCGACG-------------------IQFQFYNNLLEHMQSHAADNE--NHVKEDSPKPCPAPAGTQEQLWKSPQPAQQ----------------------------------------------------------------------------------------------------------------------------RNHMPSFQNRLLP--------------------------------EKERQQVAERLLRVMCVDLGLLGVLSSKDFLKLAQTL-----------VDTGSRNGAYSIREALGDMSSLALKQLPRMYNQVKVKVTCA----------LGSNSSLGIAVTCHSQTVGPDSCYLLTAYQVEG--------VRLRRYVLGLKEASLRES---------------PEQIHHWVQNVLSEFVMSEIRTVYVTEPRLSSLTFCGRTGICLRCAGCSLTATVQAVLGRRSLQARGLHELGELLATCRDIAATTSFNHEGK-TAEDPAAP----------PCWDAVAEALLKVHENFEATCEAYGRSKSTVPLLQGLNKHLLGTLACLLAP------LRQAALELSLERCPTLQNVLPVYLRLEKLFTSKAGEAG---------------------------------AGSKLCHYFLEALKEN--------------------------FKVERVHQVAMILDPQLKLRPVPAYQHEEIISRVCDMAASMRDLGSGGSAGASVDERDGEGPSAPKRGRLDCGLDRPSCDAEEPQVRKELFQYLGEPLFSGTGDLLQYWSSVMDRYPRLSRLALWLLAVPAVAVHGECMSICEQTLAMK---RKQQVTAE------------EMNKLVFLKSNFA--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VE54-1", "uniprot_id": "Q9VE54_DROME", "id": "Q9VE54-1", "name": "C2H2-type domain-containing protein", "aln": "MVDNSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVGNGGNSMGSVLAAAMLTGGSGGGGSSGGEASADEKPAVLSPPSGGDVKPVVVNTISAATAPVLPPAPPPLSSSLVAACSNGAASSTTSSTPTSTSASNSSSLSSSKPSNPPMKALKCSPPTTEARASTSAHPTTSSVSTLYQPAQVTPDYRFNQQQQQPQTSGFGRGVTTSTAALVIPQVPQQHFLASHQQQAHFPHQQQSPQQQQQHSQHQPALKFSYATALPPPPPLQLFTQQQQQQQQTVVPPQTQQQSHQKPPPAYGAAISQIRSQHNQNKQQPQSQSVAMQPNLALAPTTTSAASTSHATAAVKQPSKPHTEVFLNPPPPPSAQQQLQIHSLVQNQGQHHQHSHPQQSQPSQQSHQQPPSLQTYGLGVSNSCSSSNNPSTSGSGHRANRQTNSPFGALLNAAAAVACASPACPTTSSSVLRFAESPVAHYLERENGDFIVQETPKHIVECVEKEDGEFSVIERIYQSPPSVLHIHDDDEDDEDEEEEDEHDAPPEEEDGDDEREENSHSRNMSKTTKKARKTKPKRGSKRMSDEEEFMSLSSGCESDLEKEGKQEQLNAAASLPPPLCTAPSTSAAAGASTSNLADNHSNSASNSASNSNSTATTKSKKNRITVLSDVPLNMNEYLDLMGNIVASSRIGASRPFAAVAPIPLVKVEKEEPLDDYDNVAMAANEELEQKPSLEHGTTSVIRMASTAAASTSATATETSAEDLTQPPPMKVEVEATTTLLPQRFSTPAQHRGPKKLVIKPKQTAPATATTTKKTDTPSSPSNNPSISRDLVQVKSETLEAPATSSSSSILEKHLTTSRKLLHHHSAVNDDDARVLLEFANSKQPPPLAASSTTFVVNASVGFPSAGSVFASSSTSCSKAPAKPGEEYILPDNNMDVDEIVISSSSSYTSSAAQVQNTLQPPDFNFLYHQATTTATTATYFNPFSRQQQHHHQQQHGVSDATNAATLASSSSNSLDHESMNATFRVAKTQSLQSWYQQEPDHDPQNQGGAESGTVTPSNQSQDVVSHQPTNFNAALAAVDCCSVALDEDAKYLDLDACKREQLSSSSNLPSASASTTSSSFAGAGTESSLVGGLNIRTDEKMPAKGEISEQESNCDIENSWSESVYGDISQRYFRNQFSGGYHPDWRQDYYPAQDLSAQLREHKRFDFNAVDDEASSSSRRSHLTDLPTAATSSACTSSAMLAGPPIASTSRAAAEAAAEAAALAQRKPQRRKLYKCPHCEAIFEKLKERNAHMIGEHNYVRQNRRLICTQPQINTSMLTLQQQMIVQSGEVEDSKDGIVKIKQEQCQEKQDVEQMHDHSELLADVKDSELMGIGGDGDGDVDDDIKPPNQLDEKPTLPPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTP-LKCKICGKKFKRYSNLTQHRKRHTKMMVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTEPQYDCAICSKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHINAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGTKKFTCDQCDKSFHRHYYLIEHRRMHTGERPFTCTICGKSSTTKTNHNKHLKIHHSRDPFTVEA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . . . : . :. . : ... : : .: .: .: . . *: :* .. .: . * * ... : . . : * . : : :.. : * * ::. * . : . :: . . .:. : :* ** * . ** :: : .:* .*: : . . . : ..:. . : :.. : . .: . *..*. ::.: ..** : * .*::. ::: . :. ** . : ..::: . * : * ::. . * . : . . . *. * : :::*:* *. : ** * .: . .:.: * :* . . * *. *. ::. ::. *: ...:. ::: * .:: ..: :. : :::.:* :* .: * * . :*: : : .: :: * . * . . : . :*.:: * : * ::: : * : . : : : :*. :* ::. ::. :::. * * * : : * * * .: . :**. : : * : . . . : *.: . :*. : : : : :: :: . : . : . : * . . : : :. * : * :.: . * . *. * :* : : * * : : *:: .. * * :* *:.: ", "identical_positions": 80, "similar_positions": 278, "identity": "4.48%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2064", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZG06-1", "uniprot_id": "D3ZG06_RAT", "id": "D3ZG06-1", "name": "TBC1 domain family member 30", "aln": "MVKDFVELPGRSGSGGKEDSGAAPADVKPELRASAHWLAFRPLPGTLYCPRGRALTELADAAAVRVMEVLPAGRMWDSQQAEEAAGHPAGEGDPEPQPDGRTSRTASLVSGLLTELYSCTEEEDVAAGGDRSQGRPLRKDSLDSSTETSGSDVFLGGR-GAGDSRVLQELRERPSLRLQMQYLERKDSSELKTILRELKSRVGIQSAKLLRQLKQKDRLLHKVQKNCDIVTACLQAVSQKRRVDTKLKFTLEPSLGQNGFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKNVGYCQGFNILAALILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRLKLPELSQHLDTLQRTSNKESGGGYEPPLTNVFTMQWFLTLFATCLPNHTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECCETADEFYGTMGRLTQEMLEHDLLQSHELMQTVYSMAPFPFPQLAELREKYTYNITPFP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATIKPTSVSGRHSKSRDSDDENGPDDEDAVASAVGCLGPLSGLLAP------------ELQKYQKQIKEGTEEQTLRSNNIAELSP------------------------------GAINSCRSEYHAAFN-----------------------------------------------SMMTERMTTDIN-----------------------------------------------------------------------------------------------------------------------------------------------ALKRQYSRIKKKQQQQLHQVYIRAGSKEEQDLGFFLGPEDQ-------------AVDDKGPVTSILPSQANSSPVIN----------------HLLLGKKMKITNRAAKNAVIHMPGHAGGKISPVPYEDIKTKLNSPWRTHIRVHKKNMPRTKSHLGCGDTVGLIEEQNEGCKTS------------------------------------------------SLGAAEEFPSSC------------------AVTAQSEG---------------------------------------SSGDS----VTPRT-IEG---------------------------QSPEPVFGDADVDVTAVQVKLEALELNQ------RDTTAETESKG----QRHAPELVDAPGENQTVSKSLPGSNSKPP-----IFSPFPSVKPLRKSATARNLGLYGPTERTPTMHFPQMSRGFSKSGMGSSSTKKR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q69ZT9-1", "uniprot_id": "TBC30_MOUSE", "id": "Q69ZT9-1", "name": "TBC1 domain family member 30", "aln": "------------------------------------------------------------------------------------------------------------------------MRQDKLTGSLRRGGRCLKRQ---------------GGG-GVG--------------------------TILSNVLKK-RSCISRTAPRLLCTLEPG--------------------------VDTKLKFTLEPSLGQNGFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKNVGYCQGFNILAALILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRLKLPELSQHLDTLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNHTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECCETADEFYGTMGRLTQEMLEQDLLQSHELMQTVYSMAPFPFPQLAELREKYTYNITPFP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATIKPTSVSGRHSKARDSDDENGPDDEDAVASAVGCLGPLSGLLAP------------ELQKYQKQIKEATEEQTLRSNNIAELSP------------------------------GAINSCRSEYHAAFN-----------------------------------------------SMMMERMTTDIN-----------------------------------------------------------------------------------------------------------------------------------------------ALKRQYSRIKKKQQQQLHQVYIRA---------------------------------DKGPVTSILPSQANSSPVIN----------------HLLLGKKMKITNRAAKNAVIHVPGHPGGKISPVPYEDIKTKLNSPWRTHIRVHKKNMPRTKSHLGCGDTVGLIEEQSEGCKAS------------------------------------------------SLGAAEEFPSGR------------------TVTAHSEG---------------------------------------SSGDGDGGGSTPRT-IEG---------------------------QSPEPVFGDADVDVAAVQVKLEALELNQ------RDAAAETEPKVHFPCQRHASELADAPGENQTAIKLLPGSTSKTP-----IFSPFPSVKPLRKSATARNLGLYGPTERTPNVHFPQMSRGFNKSGIGNSSTKKR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2I9-1", "uniprot_id": "TBC30_HUMAN", "id": "Q9Y2I9-1", "name": "TBC1 domain family member 30", "aln": "-MDVLPTGGGRPGLRTELEFRGGGGEARLESQEEETIPAAPPAP------------RLRGAAER-------PRRSRDTWDGDEDT-------EPGEACGGRTSRTASLVSGLLNELYSCTEEEEAAGGGRGAEGRRRRRDSLDSSTEASGSDVVLGGRSGAGDSRVLQELQERPSQRHQMLYLRQKDANELKTILRELKYRIGIQSAKLLRHLKQKDRLLHKVQRNCDIVTACLQAVSQKRRVDTKLKFTLEPSLGQNGFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECCETADEFYSTMGRLTQEMLENDLLQSHELMQTVYSMAPFPFPQLAELREKYTYNITPFP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATVKPTSVSGRHSKARDSDEENDPDDEDAVVNAVGCLGPFSGFLAP------------ELQKYQKQIKEPNEEQSLRSNNIAELSP------------------------------GAINSCRSEYHAAFN-----------------------------------------------SMMMERMTTDIN-----------------------------------------------------------------------------------------------------------------------------------------------ALKRQYSRIKKKQQQQVHQVYIRA---------------------------------DKGPVTSILPSQVNSSPVIN----------------HLLLGKKMKMTNRAAKNAVIHIPGHTGGKISPVPYEDLKTKLNSPWRTHIRVHKKNMPRTKSHPGCGDTVGLIDEQNEASKTN------------------------------------------------GLGAAEAFPSGC------------------TATAGREG---------------------------------------SSPEG----STRRT-IEG---------------------------QSPEPVFGDADVDVSAVQAKLGALELNQ------RDAAAETELRVHPPCQRHCPEPPSAPEENKATSKAPQGSNSKTP-----IFSPFPSVKPLRKSATARNLGLYGPTERTPTVHFPQMSRSFSKPGGGNSGTKKR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58J973-1", "uniprot_id": "A0AC58J973_DANRE", "id": "A0AC58J973-1", "name": "TBC1 domain family member 30", "aln": "-MSAAVEVAKEELKEVNICDICPEEESGVFLSAGASYLDG--------------FSGFHKWVSKIEVSDGDCEKTSSRKAHEEEKG-----GLYFDREELKDSRASSLVDCLLVELY---DTYSHGVPGLDSSTEASSSD-------------AFLGRSNSGSS-FLQELQEKHTRRHQVKYLAQKGPEELKWIVQEVKYRIAVQSAKLVRQAKRKDRLRQKFQKNCDIVTACLQAVSQKRRVDTRLKFTIEPSLGKNGFQQWYDALKAVARLPVGIPKEWRKRVWLTLADQYLHSISIDWEKTMRFAFNDRSNPDDDSLGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNVLAALILEVTEGNEGDALKVMIYLIDKVLPDSYFANNLRALSVDMAVFRDLLRLKLPELSQHLHHLQKVANREAGGSYEPPLTNVFTMQWFLTMFATCLPHHTVLKIWDSVFFEGSEMLLRVALAIWAKLGERIEECQTADEFYSIMGCLTQEMLEHKLIDSNELMQTVYSMAPFPFPQLAELREKYTYNITPFP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APVRANSSLALHG--WESDDDADMDDEDSIVTALGCLGPLGGLLAP------------EIQRYQRHLKDQRAEQSCNGSNMAELSP------------------------------GAVGAGRAEHQAAIN-----------------------------------------------SMMLERMSTDIS-----------------------------------------------------------------------------------------------------------------------------------------------ALKKQYSRIKQKQQQQAGLLYIHTGLPVEAETIEPHQSSKQQIYHTGTDTYGSTYNIDKCPATSVLASQIGPSPVVN----------------HLLLGRRPRPCERSLKNGMIHNGGSPQSHSTPLLDQMVRSRHHSPWRTHVRAHRRNIARARAQLGFDDSLEAEDDQTDESKTEGASMEGE---------ETKSEEADEDKIENTAAGGSDVSKQELQEIDRQLSALELDPESSPDPSTPEPALDPDPQSDPTITPEPQADPNPTTPDPDPTIQDPSFTIQNPNSTIQNPSPTIQESKPTTKDSCFTIQNPNS-IVQSPSSAVQNPSLAIQNPNTIVQNPNSSIQNPNPTIQDPNPTDQNPNSSIQNLNITI------QDVNPTTPPQAPLTSSRRPGSDSSSSESGSSLRRSASSLAGDPPKAQQQIYSPFPCIKTPRKSTAARNLGLYGPTARTPNVHFPQMSRSMNRVG---NTTKRR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4LH08-1", "uniprot_id": "A0A0B4LH08_DROME", "id": "A0A0B4LH08-1", "name": "TBC1 domain family member 30", "aln": "------MSETKKLLDALLCDIYGRQE-------------------------------VLAKRIRRCCRDPVHKRSPKKKKGQLAQLASGMVGDRSSLERLDVRKLIDVCAILKVEILMLGYLLERVLVARDRLQRHQEVLC------------------EFVTAVLIVESDDAQPKMRFSLSPPPQKAITSARLTSPTKNSLSSNNTITTPGSNNRSPSSTKTTMLTRNGGGHGTSPTASGSGHAPSATAAADDEATSDYNQWLHAMKLVARLPGGTPPEFRRKLWLSLADKYLKSKNVDWAQQREKCFCEEWREDDEELGIQIVKDLHRTGSNLCTGPAGSINQAKLKRILLGYARYNPEVGYCQGFNMLGALILQVMDKEEEESMKVMIYLVEGVLPTGYFYGSMGGLQADMGVFRELMQTRLPRLAKHLQRLQGPVEN----AFEPPLTNVFTMQWFLTMFCTCLPMSCVLRVWDLVLIEGSDVLLRTALVLWSLLEERVISVRSADEFYGKMGSYSSELLNGHLVDSNGLIERVVKLG--PIEDLRQLRDKHLYNIAPLRHKQGLQLYYDEEDTHSDEERLAVATVFGLNWGRRGSVGPAAAGKQQVEQKDRLALDISLLKKQYDRLRERQKQAHVILTTACSTAARQGSGPASSSQPAVPVNQLLLGRPAIVTNKGKRVGAPLGAIPPARKPSLPAVLHTKPTSEKQLRRGETLLWRDTDPSRRRRDSLTWKEIKADRAAMIREGVDVSSVRTQKLRTRFGKSDSSSYSEDSDGEQESGTGGGGGSSTDTSLCDDDDPKSTEKSPKQKAKLARKLKEQKQLAGSRETSLERQRPKSWAPSSHEIPFMLMGTDSGDEKEDKSTKEGPITGDQAEDSATESGHYEFDRELHLVSSKMEPLKLPFDPEFTGMTSVSPIPTPREKSEAEEDLLDERKPFDVSDDGVTNQYFERVNSVERPNRLELTYSLNEEETDTNAIYLEEREKVEGHSGDREYNSLPPFYPRENDDGVQGGGKVPQIRDDNIPGENKDDYKELLSMTIEENTVYKPPTPTASTLSNASRKRRDPRRKTLTRSSTIEIEERYQALERRISQDQPSGDRQAKYIPSTAALEERFNTLEKQLSAEKQRKELSEMEAEYPIKSERIPSTADLESRFNSLTKQMSSSESSSKTPIDLKDEDRPSGSSSKNQKDSEKTSKLHKSEEPESNTKETTGETEASDSNDSKIGEKETEQPRIKKLPSTAELEDRFNALERKMSVQKSSPSKNKKEPPDEEESKSTKEPEEPEESEKANEKTSGRQTPIAKKDSKDSDQKKSETKENQSPTKNQDEKVKVKSPKSEEMIEKETSSNPKEDSHESEAATNKKVEGNRELSSEKGDHKIKEKSEEAPGKAGKETAETKNANVKDSSKKGDSQKNEAAKTSVSQTESDLKPSSKENSTSKDAEQEKTPRKSPPSTEELEKRFNALEKQMSTTNLETTKEPDQTKPATKSQSTSAEVKTQKSMKSFDDKIKEVNVAIEKEQSRVEVEVNAEKKRKNVEEAPKNKEGDSQQPEESQHKGKNQRRASEPPSTEDLEKRYETLKRRMSSKNQFSETVDEALERIQQEVISEAVEEKKPPPSTEDLESRFEALHGDKKNVESKMDETKHVDVAIEAHIPSPPPPPPPPKERPVLAEPVLHQQQALIEELQSKMRGQSPGEENLKPSEINPQRRQKKLLQRPTPMGDETSEAPANTAYYRAANHEQWQQRMVRRFSDLPSRADLENRLQFLERQLYKKFYKQRCASDSEVASRVKLPPEDQPSTSRQARKQEAEGQLEQRVLALEKQLSENSLKLLEAMRERHRSADDSGSPRRLSTETIDATGKELVRYTQNIGELEEVDAHKPINISINIKMMVNKDSESKQPKGESKPTTEDLTRRLEQLEQQLLEERAKNGSIPPENEVLEEKPEKLEEKDSCKKQEKNCHNQHVKGDEVEKTEIPADRKIEPASAKETKTLENVEKAQTRAKVVDTEKSVKDQNAVTDEKSVQDQNVVVDKKADRKILDKKDKSPAAGKSEDTKQTSGKKEKSEDIKQASEAPKAGASKETSTRGKPSETKLEKPTTKESVLKETFPKKENLESEKPKSKENEATKTETQKSKETPTVAVSPKESKVSSKQMTEKKETIKDSSSKELPEKMVINSTDVGPMDPNGKTVVLLMDNEHRASKVRRLTRANTEELEDLFQALEKQLNDRNLVKSEDGRLIRVDPKPSAEQVEQTQAISDLTKEIEDFTSAKPEEENPKEAAKEDKPEPEEPEDFDWGPNTVKHHLKRKTVYLPSTKELESRFRSLERQIKLLEDVEKIDVEQRLNEIERKIKLQYSLSHEKDLNKYLELCEGKGLDDDEPVPVETPTKEAEITTARDRSRSPGRKALATKSPYTSPSRKATIKTPHTSPTRKPIIKSPYTSPSRKSAKSPYTSPSRNRQRSPSPTRSPERKSKKSPYTSPARRKPHPNDLPISDDLEYKYRVLDLVRSKSKENLAKRMNDPNRKPAIHPLEMILSPSPDADAIPTTGELEHRIRVLDEKLKSPAKTRSKSRSRSPTIEDIKRQKMRDEKKPRTPVHNLERIVSSPGRPEPPTAEELEERIRILEQEHKFDFKTQKDYKAFNQKLKDVISPSLSFDEFRAAKSREQSPRRHGPTTPKSALRRDDFDEGYCGGTHTSTLYRPTSPKVIRFRDEDEDEDQFEEAPRPKSRQTSDRMVGTTHDVLDCLTENTKILQRILKKTLADQPSATRSYASSTEGLDALGSRLMRETSPITRTGTHTGVPLRTGENINDRLSSIKNSIKSIDTLCEEKPYQKEKCQRYIDSLFTDSLHFASKKSSLEDLSLSRSLSRSESRGRSIHRSGDYAPSIRVTSEHRSLGSADSRRSPLGNRDTSPLHHRSHRDISRELSPRRRRLEEEDEERKDRESSRVRRDNLLPNYFADNRSELSSGSSLTGFNHKVDRQLEETCAKYADDRRSACRTPLSHPYESRTTATRHSHTDPVQIPTNPAGSATATDSFPRPVSPYRQPYDPYHRSPGGAGGTPLYQPGKLEIRHTTVTSTFYDRFLTEKQIERQTHSRPPSRSPVVSPSVPAKSYVELCSTSGTSSTTATSTSTSSFMSSSYAGPSFSLPSASNFSYLNPGSGSGSGISSISPRASCSDLRSTTSGPTSTSTTSVTTSSYVPYNFTSSFTSRLNDPIITSTTSAVSTSSLTHSTGVYNPMMSFTLREPLASSSLGGSSASPLLPFQFNRTFTSNFDKEQNKQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : : :. . : .: : . . ..::** .*:* ****. * * *:*:::**:***:**:* :** : . * :. . **:.:************.. * .. ::. ***:**.***:* ********:*.****:* : :* :::*:****:: *** .** ..: .*..**.***:*:: :**.*::**. ** :. .:***************:*.**** **::** *::***:::**.:*.:*: * *:: .:*****. ** :.*:*: .*::*: *:: * .:. *: :* :**:*: ***:*: :.::. . .. .*. . . *.*: .. * .. . *. : : :::*: . ..: . * *.: . ::* *: . .:: ** . *:. **::: *: : . ::* : : :: * *: * *: .. . . * : : : *.. :* . .: . : : :.. . ...: .: : : * . : : . *:. * . .. . . . .: : .. :.. *.: : :: :: . . . : .:. : . .. * . . :: :: *: .*. : : *: *: .: . . ", "identical_positions": 175, "similar_positions": 258, "identity": "5.35%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2066", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZBP2-1", "uniprot_id": "D3ZBP2_RAT", "id": "D3ZBP2-1", "name": "Paired amphipathic helix protein Sin3a", "aln": "-MKR-RLDDQESPVYAAQQRR-------------------------------------IPGSTEAFSH-----QHRVLAPAP-----------------------PVYEAVS-------------------------------------------------------ETMQSATGIQYSVA----PNYQVSAVPQSSGSHG---------------PAIAAVHS-SHHHPAAVQPHGGQVV-----QSHAHPAPSVAPVQGQ-------------QQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGFNTFLPPGYKIEVQTN----DMVN-------------VTTPGQVHQIP------------------------------------------------THG----IQPQ----PQPPPQHPSQPSAQ--------SAPTPAQPAPQP--------TPAKVSKPSQLQAHTPASQQT----------------PPLPPYASPRSPP---------------VQPHTPVTISLGTAPSLQNNQPVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYAQVARLFKNQEDLLSEFGQFLPDAN-------------------------------------------SSVLLSKTTAEKVDS----------------------------------------------------------------------------------------------------------------VRNDHGGTVKK--------------------------------PQLNNKPQRPSQNGCQIRRHSG------TGATPPVKKKPKLISLKESSMADASKHGVGTESLFFDKVRKALRSAEAYENFLRCLVIFNQEVISRAELVQLVSPFLGKFPELFNWFKNFLG---------YKESVHLESFPKE---------------RATEGIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKEVLNDTWVSFPSWS-EDSTFVSSKKTQYEEHIYR----CEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYA-DKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLLNEIESIYDERQEQATEENAGVPVGPHLSLAYEDKQILEDAAALIIHHVKRQTGIQKEDKYKIKQIMHHFIPDLLFAQRGDLSDVEEE----------EEEEMDVD---------------------------------------EATGAPKKHNG----------------VGGSPPKSKLLFSNTAA--QKLRG------------------------------------------------------------------MDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDSSQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEVCVQVTDLYLAENNNGATGGQLSSQTSRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIELLDTEEENSDDPVEAEVWTRWSDYVERYMS------------------------------SDTTSPELREHLA-----QKPVFLPRNLRR----------IRKCQRGREQQE-------------------------KEGKEGNSKKTMENVESLDKLECR----------FKLN---------SYKMVYVIKSEDYMYRRTALLRAHQSHERVSKRLHQRFQAWVDKWTKEHVPREMAAETSKWLMGE----------GLEGLVPCTTTCDTETLHFVSIKKYRVKYGTVFKAP----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60520-2", "uniprot_id": "SIN3A_MOUSE", "id": "Q60520-2", "name": "Paired amphipathic helix protein Sin3a", "aln": "-MKR-RLDDQESPVYAAQQRR-------------------------------------IPGSTEAFSH-----QHRVLAPAP-----------------------PVYEAVS-------------------------------------------------------ETMQSATGIQYSVA----PNYQVSAVPQSSGSHG---------------PAIAAVHS-SHHHPTAVQPHGGQVV-----QSHAHPAPPVAPVQGQ-------------QQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGFNTFLPPGYKIEVQTN----DMVN-------------VTTPGQVHQIP------------------------------------------------THG----IQPQ----PQPPPQHPSQPSSQ--------SAPTPAQPAPQP--------TAAKVSKPSQLQAHTPASQQT----------------PPLPPYASPRSPP---------------VQPHTPVTISLGTAPSLQNNQPVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYAQVARLFKNQEDLLSEFGQFLPDAN-------------------------------------------SSVLLSKTTAEKVDS----------------------------------------------------------------------------------------------------------------VRNDHGGTVKK--------------------------------PQLNNKPQRPSQNGCQIRRHSG------TGATPPVKKKPKLMSLKESSMADASKHGVGTESLFFDKVRKALRSAEAYENFLRCLVIFNQEVISRAELVQLVSPFLGKFPELFNWFKNFLG---------YKESVHLESFPKE---------------RATEGIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKEVLNDTWVSFPSWS-EDSTFVSSKKTQYEEHIYR----CEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYA-DKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLLNEIESIYDERQEQATEENAGVPVGPHLSLAYEDKQILEDAAALIIHHVKRQTGIQKEDKYKIKQIMHHFIPDLLFAQRGDLSDVEEE----------EEEEMDVD---------------------------------------EATGAPKKHNG----------------VGGSPPKSKLLFSNTAA--QKLRG------------------------------------------------------------------MDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDSSQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEVCVQVTDLYLAENNNGATGGQLNSQTSRSLLESAYQRKAEQLMSDENCFKLMFIQSQGQVQLTVELLDTEEENSDDPVEAERWS---DYVERYMS------------------------------SDTTSPELREHLA-----QKPVFLPRNLRR----------IRKCQRGREQQE-------------------------KEGKEGNSKKTMENVESLDKLECR----------FKLN---------SYKMVYVIKSEDYMYRRTALLRAHQSHERVSKRLHQRFQAWVDKWTKEHVPREMAAETSKWLMGE----------GLEGLVPCTTTCDTETLHFVSINKYRVKYGTVFKAP----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96ST3-1", "uniprot_id": "SIN3A_HUMAN", "id": "Q96ST3-1", "name": "Paired amphipathic helix protein Sin3a", "aln": "-MKR-RLDDQESPVYAAQQRR-------------------------------------IPGSTEAFPH-----QHRVLAPAP-----------------------PVYEAVS-------------------------------------------------------ETMQSATGIQYSVT----PSYQVSAMPQSSGSHG---------------PAIAAVHS-SHHHPTAVQPHGGQVV-----QSHAHPAPPVAPVQGQ-------------QQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGFNTFLPPGYKIEVQTN----DMVN-------------VTTPGQVHQIP------------------------------------------------THG----IQPQ----PQPPPQHPSQPSAQ--------SAPAPAQPAPQP--------PPAKVSKPSQLQAHTPASQQT----------------PPLPPYASPRSPP---------------VQPHTPVTISLGTAPSLQNNQPVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYAQVARLFKNQEDLLSEFGQFLPDAN-------------------------------------------SSVLLSKTTAEKVDS----------------------------------------------------------------------------------------------------------------VRNDHGGTVKK--------------------------------PQLNNKPQRPSQNGCQIRRHP-------TGTTPPVKKKPKLLNLKDSSMADASKHGGGTESLFFDKVRKALRSAEAYENFLRCLVIFNQEVISRAELVQLVSPFLGKFPELFNWFKNFLG---------YKESVHLETYPKE---------------RATEGIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKEVLNDTWVSFPSWS-EDSTFVSSKKTQYEEHIYR----CEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYA-DKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLLNEIESIYDERQEQATEENAGVPVGPHLSLAYEDKQILEDAAALIIHHVKRQTGIQKEDKYKIKQIMHHFIPDLLFAQRGDLSDVEEE----------EEEEMDVD---------------------------------------EATGAVKKHNG----------------VGGSPPKSKLLFSNTAA--QKLRG------------------------------------------------------------------MDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDSSQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEICVQVTDLYLAENNNGATGGQLNTQNSRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIELLDTEEENSDDPVEAERWS---DYVERYMN------------------------------SDTTSPELREHLA-----QKPVFLPRNLRR----------IRKCQRGREQQE-------------------------KEGKEGNSKKTMENVDSLDKLECR----------FKLN---------SYKMVYVIKSEDYMYRRTALLRAHQSHERVSKRLHQRFQAWVDKWTKEHVPREMAAETSKWLMGE----------GLEGLVPCTTTCDTETLHFVSINKYRVKYGTVFKAP----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F0R9-1", "uniprot_id": "E7F0R9_DANRE", "id": "E7F0R9-1", "name": "Paired amphipathic helix protein Sin3a", "aln": "-MKR-RLEDQD--TVIGSQRR-------------------------------------LPGGVDSF-------QHRVLNSAS-----------------------SLFETAAP------------------------------------------------------ETMQPSSSMQYSVS----QTYQLS-MPQNSGGHGH--------------TSSSAVHTGPHHHGPAVQPVG---------QAHSHATPAPAPTLGQ-------------QQFQRLKVEDALSYLDQVKLQFGNQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGFNTFLPPGYKIEVQTN----DLVN-------------VTTPGQIHHIT------------------------------------------------PHG----ISVQNIPITQPAPHQP-QPAPP--------TSTAALVIPSQP--------TPAKISKPMQSPALTPTSQPN----------------PSIPSYASPRSPS---------------VQSHTPISSSTAGSTPLQNNQPVEFNHAINYVNKIKNRFQGQPEVYKSFLEILHTYQKEQRNAKEAGGNYTPTLTEQQVYAQVAQLFKNQEDLLSEFGQFLPDAN-------------------------------------------SSVLLSKTTAEKAEA----------------------------------------------------------------------------------------------------------------VRIDHGGTVKR--------------------------------PQLNNK-QRFNQNGCQIRRHSG------PPTTPPVKKKQK-FAVKDPSVAEASKLGIGAESLFFEKVRKALRSSEAYDNFLRCLVIFNQEVISRAELVQLVLPFLGKFPELFTWFKNFLG---------YRECAHIESFPKE---------------RATEGIAMEIDYASCKRLGSSYRALPKSFQQPRCTGRTPLCKEVLNDTWVSFPSWS-EDSTFVSSKKTQYEEHIYR----CEDERFELDVVLETNLATIRVLEAVQKRISRMSAEEQAKFRLDNTIGGSSEVIHRKAIQRIYG-DKAPDIIDGLKTNPAVSVPIVLKRLKIKEEEWREAQRGFNKIWREQNEKYYLKSLDHQGINFKQNDTKVFRSKTLLNEIETLYDERQEQASEDNAAVPSGPHMTLMYEDSQILEDAAALIIHHVKRQSGIHKDDKYKIKQIIYHFIPDMLFARRGELSDVEEE----------DEEETEPD---------------------------------------EDG--TKKHNG----------------TTSS--KSKLLFSHTAASQQKLSS------------------------------------------------------------------CDDAYNLFFVNNNWYIFLRLHYILCSRLLRIYGQAEKQIEEDTREREWERNVLGLKREKNDSPAIQLRLKEPMDIEVEDYYSAFLEMVRNLLDGNMETSQYEDQLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDDICVQVTDLYLSECANKATGGSLSTQSSRSNAETSYQRKSEQLMSDENCFKLLFQKSKGTVQLAVELLDTEEENSDGPVDTERWP---DYVERYLN------------------------------TSSASPELREHLS-----QKPVFLPRNLRR----------IRKCQRGQEMQM-------------------------REAKETAKKSSEGGDDS--KMECM----------FKLN---------SYKMVYVFKSEDYMYRRTAQLRAHQSHQRVSTRLHQRFQMWLDRWRKEHVTSDMAATNHKWLMGE----------GQDGLLPCRTVCEPKILHFQNINKYKVTYSTTS-------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K765-1", "uniprot_id": "A0A0B4K765_DROME", "id": "A0A0B4K765-1", "name": "Paired amphipathic helix protein Sin3a", "aln": "MMKRTRVDEVQFGTRPVPQTSGGVGVGVVGVTGGGPTSGGGGTATVGVNTTGVTIGTVVPSAHNATISGIGSIHHRILTPQHGGAQTIAYLPSTTPTATNLKTTTSIVDSTTAGGPVGAGAQVAVGVGSAAGGGGVVVSTGSTGTQTLQYTTSYSVASIQAGGTLKANTADGANTVQIHVTGGGAANNPASAQTVSSSSQTGTIRQRTISGTQTVATAVGNLATISQQQPVQQSPLGKAQTPPSSVVANSIPVGGTTPPQGQSG-----------NATPRLKVEDALSYLDQVKYQYADQPQIYNNFLDIMKEFKSHCIDTPGVIERVSTLFKGHTELIYGFNMFLPPGYKIEIHSD----ALGCSVPVVSMPSPPGAPTSTGTVHMLTGNSSMSGAGHIAIKTTNAATLTPAAGAGAAAAAAAVAQIQSAGAVNLMTHGGASLTQTTIHALQQATPPQSQSPGGGHVHVSVTNSTAANAVVPGQPGISVSAHNVPQNYSRDRERATITPTGQVAGAAANVNASASIVVGGPPTPNSLSELSPHGGAGGGPGAGAAQHNLHHIQQAHQSILLGETGQQNQPVEFNHAITYVNKIKNRFQNQPAKYKKFLEILHDYQREQKVMKEGSLNQGKMLTEQEVYTQVAKLFGQDEDLLREFGQFLPDATNHQSGQYMSKSASVHNDHGKRPTATLSGGAHITMSSASPAPSGSPLHLGATTLPQIDKSAHAAAIGNLSAVNTSVSIKTYNNNQQQQNHVIGSGLNATRNDILFEKDYHAGLQQQAHQRGAGVGGHHHLAGTAAGANIGRPGVGASVMVSYDKEHRNNHHVQKYVGHAPNQNLTHGHNAKKSPSYGIPSVIGSMPHISDNSLDRSSPGISYATPPLPSGPHGQHNSGSATRRPGDDSLVGHYASGAPPAKRPK-PYCRDVSFSEASSKCTISDAAFFDKVRKALRSPEVYDNFLRCLTLFNQEIVSKTELLGLVSPFLMKFPDLLRWFTDFLGPPSGQPAGGLIDGMPLAATQRQGGGSSNSSHDRGTSHQSAAEYVQDVDLSSCKRLGASYCALPQSTVPKKCSGRTALCREVLNDKWVSFPTWASEDSTFVTSRKTQFEETIYRNIHRTEDERFELDLVIEVNSATIRVLENLQKKMSRMSTEELSKFHLDDHLGGTSQTIHQRAIHRIYG-DKSGEIITGMKKNPFVAVPIVLKRLKVKEEEWREAQKTFNKQWREQNEKYYLKSLDHQAINFKPNDMKALRSKSLFNEIETLYDERHDQ--EDDAMEPFGPHLVLPYKDKTILDDAANLLIHHVKRQTGIQKQEKQKIKQIIRQFVPDLFFAPRQPLSDDERDDAFPFLVD--DNTKMDVDSPLGRTESSTRNAKSTPSESASPARSNASTSSVTPAGIKKETDDSKATTGSFAPASSATASSATPVDDATPSTSSAAAAASAASSSTVSGTEGKPKDDPLSSHKEEGAGSTSSGVATSPRQAQDTAGAGVDVEIKLEHPADFSNPKLLPPHAHGQREDESYTLFFANNNWYLFLRLHAILCDRLHVMYERARLLAIEEERCR----------VNRRESTATALRLKPKPEIQVEDYYPTFLDMLKNVLDGNMDSNTFEDTMREMFGIYAYISFTLDKVVSNAVRQLQYCVTERAALDCVELFATEQRRGCTGGFCRDAHKTFDREMSYQRKAESILNEENCFKVYIYKID--CRVTIELLDSEPEEVDKPAALKAQKFS-KYVERLANPALGGGGNTGRSDSALGNDSVVDGSDIKTEADEDTAELRYREGGIGGAGKARFLVRNKRRSKLLEEQVRQLFEHRRNRIEQHGTAASLEPISVDSAISSNSTTGGGGSGTNNNNNNNNNNNSWGGKRLERLGAPQVGLAEQYAFNDRDEISTNISNGRCFVTSKNLKLLKYDAVRRAKKSHCRVTQAKYAHFQTYVNKWLQQHVSEQQQQNCVDWLLGKTADQINASGWGSASKTKTVQQKDTSKTPYRIYNRYRVVQSAVSGGLMSATAPTPDGSVPAVNSAPSGSVSTVNNVQGSAAVSSTSHSMCNSSILSADSTTNTNASAQQQQHCNSAAAATTPNAEALQQVRPMES", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22579-1", "uniprot_id": "SIN3_YEAST", "id": "P22579-1", "name": "Transcriptional regulatory protein SIN3", "aln": "MSQVWHNSNSQSNDVATSNDATG-------------------------SNERNEKEPSLQGNKPGFVQQ----QQRITLPSLSALSTKEEDRRDSNGQQALTSHAAHILGYPPPHSN---------------------------------AMPSIATDSALKQPHEYHPRPKSSSSSPSINASLMNAGPAPLPTVGAASFSLSRFDNPLPIKAPVHTEEPKSYNGLQEEEKATQRPQDCKEVPAGVQPADAPDPSSNHADANDDNNNNENSHDEDADYRPLNVKDALSYLEQVKFQFSSRPDIYNLFLDIMKDFKSQAIDTPGVIERVSTLFRGYPILIQGFNTFLPQGYRIECSSNPDDP---------------IRVTTPMGTTTVN-------------------------------------------------NN----ISPSGRGTTDAQELGSFPESDG-------NGVQQPSNVPMVP--------SSVYQSEQNQDQQQSLPLLATS---------------SGLPSIQQPEMPA----------------HRQIPQSQSLVPQEDAKKNVDVEFSQAISYVNKIKTRFADQPDIYKHFLEILQTYQREQKPIN-------------EVYAQVTHLFQNAPDLLEDFKKFLPDSSASAN------------------------QQVQHAQQHAQQQHEAQMHAQAQAQAQAQAQVEQQKQQQQFLYPASGYYGHPSNRGIPQQNLPPIGSFSPPTNG----------------------------------------------STVHEAYQDQQHMQPPHFMPLPSIVQHGPNMVHQG-------------IANENPPLSDLRTSLTEQYAPSSIQHQQQHPQSISPIANTQYGDIPVRPEIDLDPSIVPVVPEPTEPIENNISLNEEVTFFEKAKRYIGNKHLYTEFLKILNLYSQDILDLDDLVEKVDFYLGSNKELFTWFKNFVG---------YQEKTKCIENIVH--------------------EKHRLDLDLCEAFGPSYKRLPKSDTFMPCSGRDDMCWEVLNDEWVGHPVWASEDSGFIAHRKNQYEETLFK----IEEERHEYDFYIESNLRTIQCLETIVNKIENMTENEKANFKLPPGLGHTSMTIYKKVIRKVYDKERGFEIIDALHEHPAVTAPVVLKRLKQKDEEWRRAQREWNKVWRELEQKVFFKSLDHLGLTFKQADKKLLTTKQLISEISSIKVDQTNKKIHWLTPKP-KSQLDFDFPDKNIFYDILCLADTFITHTTAYSNPDKERLKDLLKYFISLFFSISFEKIEESLYSHKQNVSESSGSDDGSS------------------IASRKRPYQQEMSLLDILHRSRYQKLKRSNDEDGKVPQLSE-------PPEEEPNTIEEEELIDEEAKNPWLTG------------------------------------------------------NLVEEANSQGIIQNRSIFNLFANTNIYIFFRHWTTIYERLLEIKQMNERVTKEINTRS-------TVTFAKDLDLLSSQLSEMGLDFVGEDAYKQVLRLSRRLINGDLEHQWFEESLRQAYNNKAFKLYTIDKVTQSLVKHAHTLMTDAKTAEIMALFVKDRN--------ASTTSAKDQIIYRLQVRSHMSNTENMFRIEFDKRTLHVSIQYIALDDLTLKEPKADEDKWKYYVTSYALPHPT--------------------------------EGIPHEKLKIP---------FLERLIEFG-------QDIDGTEVDEEFSP-------------------------EGISVSTLKIKIQPITYQLHIENGS---------YDVFTR------KATNKYPTIANDNTQKGMVSQKKELISKFLDCAVGLRNNLDEAQKLSMQKKWENLKDSIAKTSAGNQ---------GIESETEKGKITKQEQSDNLDSSTASVLPASITTVPQDDNIETTGNTESSDKGAKIQ-------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: : : : . . ::*: . . . .. :. . : . . .:.. . . :.. . . . .: *:*:******:*** *:..:*::** ******:***:.*******.*** **:*:. ** *** *** **:** :: *:. : :. . :. . . . * . *. : : . . * . * : * ::* ***.:**.******.** .** ** *****: **:**: : :**:**::** : *** :* :****:. : : : : : ** . : . : : . : : . .. : **:*.:: : . . * :**: * ::.*:::. :*: * :* . :*: **.:*:* : . :* *: :*.** **:* *:** :* ***** **..* *: *** *:: :*.*:** ::: *:**.* *. :* * **: ** : :::..:: :* ::*:* :* :* .*:::.::::* ::. :** .:: :* ::.*:****** *:****.**: :** *** ::* ::***** .:.** * * : :* *:.**.:: :: :: . : * .:: : : *. *: * * .:.: :. : :* ::*::: *:. :: :.: . .: . : : * . .. * : . : ::.*.* *:*:* : ** : . * : . : :. ** * .* : : :::*::: . :*: :*: : *: :*:**: .. *:: : ::: : *: : . : . : . ** *:: : : : ** : . : .*. . .. : : ** * . : . .. . . : . ::* : . : . .: : : *: . :: :: : . *: * . . . . * .: ", "identical_positions": 243, "similar_positions": 358, "identity": "11.57%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-207", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LE57-1", "uniprot_id": "A0ABK0LE57_RAT", "id": "A0ABK0LE57-1", "name": "Protein NDNF", "aln": "--MMELLYWCLLCLLLPLTSRTQKLPTRDEELFQMQIRDKALFHDSSVIPDGAEISSYLFRDTPRRYFFMVEEDNTPLSVT-VTPCDAPLEWKLSLQELPEESSADGSGDPEPLDQQKQQMTDVEGTELFSYKGNDVEYFLSSSSPSGLYQLELLSTEKDTHFKVYATTTPESDQPYPDLPYDPRVDVTSIGRTTVTLAWKQSPTASMLKQPIEYCVVINKEHNFKSLCAAETKMSADDAFMVAPKPGLDFSPFDFAHFGFPT--DNLGKDRSFLAK--PSPKVGRHVYWRPKV-DIKKICIGSKNIFTVSDLKPNTQYYFDVFMVNTNTNMSTAFVGAFARTKEEAKQKTVELKDGRVTDVVVKRKGKKFLRFAPVSSHQKVTLFIHSCMDTVQVQVRRDGKLLLSQNVEGIRQFQ----LRGK---PKGKYLIRLKGNKKGASMLKILATTRPS-KHAFPSLPDDTR-IKAFDKLRTCSSVTVAWLGTQERRKFCIYRKEVGGNYSEEQKRRERNQCLGPDTRKKSEKVLCKYFHSQNLQK---AVTTETIRDLQPGKSYLLDVYVVGHGGHSVKYQSKLVKTRKVC---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C119-1", "uniprot_id": "NDNF_MOUSE", "id": "Q8C119-1", "name": "Protein NDNF", "aln": "---MELFYWCLLCLLLPLTSRTQKLPTRDEELFQMQIRDKEFFHDSSVIPDGAEVSSYLFRDTPRRYFFMVEEDNTPLSVT-VTPCDAPLEWKLSLQELHEGSSADGSGDPELLDQQKQQMTDVEGTELFSYKGNDVEYFLSSSSPSGLYQLELLSTEKDTHFKVYATTTPESDQPYPELPYDPRVDVTSFGRTTVTLAWKPSPTASILKQPIEYCVVINKEHNFKSLCAAETKMNADDAFMVAPKPGLDFNPFDFAHFGFPT--DNLGKDRSLLAK--PSPKVGRHVYWRPKV-DIQKICIGNKNIFTVSDLKPDTQYYFDVFMVNTNTNMSTAYVGAFVRTKEEAKQKTVELKDGRVTDVFVKRKGKKFLRFAPVSSHQKVTFFIHSCMDAVQVQVRRDGRLLLSQNVEGIRQFQ----LRGK---PKGKYLIRLKGNRKGASKLKILATTRPS-KHAFPSLPEDTR-IKAFDKLRTCSSVTVAWLGTQERRKFCIYRKEVDGNYSEDQKRREQNQCLGPDTRKKSEKVLCKYFHSQNLQK---AVTTETIRDLQPGKSYLLDVYVVGHGGHSVKYQSKIVKTRKVC---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TB73-1", "uniprot_id": "NDNF_HUMAN", "id": "Q8TB73-1", "name": "Protein NDNF", "aln": "---MVLLHWCLLWLLFPLSSRTQKLPTRDEELFQMQIRDKAFFHDSSVIPDGAEISSYLFRDTPKRYFFVVEEDNTPLSVT-VTPCDAPLEWKLSLQELPEDRSGEGSGDLEPLEQQKQQIINEEGTELFSYKGNDVEYFISSSSPSGLYQLDLLSTEKDTHFKVYATTTPESDQPYPELPYDPRVDVTSLGRTTVTLAWKPSPTASLLKQPIQYCVVINKEHNFKSLCAVEAKLSADDAFMMAPKPGLDFSPFDFAHFGFPS--DNSGKERSFQAK--PSPKLGRHVYSRPKV-DIQKICIGNKNIFTVSDLKPDTQYYFDVFVVNINSNMSTAYVGTFARTKEEAKQKTVELKDGKITDVFVKRKGAKFLRFAPVSSHQKVTFFIHSCLDAVQIQVRRDGKLLLSQNVEGIQQFQ----LRGK---PKAKYLVRLKGNKKGASMLKILATTRPT-KQSFPSLPEDTR-IKAFDKLRTCSSATVAWLGTQERNKFCIYKKEVDDNYNEDQKKREQNQCLGPDIRKKSEKVLCKYFHSQNLQK---AVTTETIKGLQPGKSYLLDVYVIGHGGHSVKYQSKVVKTRKFC---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QPX0-1", "uniprot_id": "NDNF_DANRE", "id": "F1QPX0-1", "name": "Protein NDNF", "aln": "---MTWRCGCYGLVLLVLGVMGQKLPTRDEGLFQMQIRDKAQFHDSSVMPDGAEISGYLFRDTPKRYYFVVEEDNTPLLVT-VTPCDAPLEWRLTLQELPEDRSGEGSGEPEPLEQQKQQVTANEGTELFTYKGNDVESFISSSSPSGLYQLEIISTEKDSNFKIYSTTTPESDQPYPELPYDPRVDVTALGRTTVTLAWKPTPTGSVMGQPIQYCVVINKEHNFKSLCAAEAKMSLDDAFMIAPKPGRDFSPFDFAYFGFVPSENDFHKDRFLTTNRALSNKMSRAYIPKPKVADIQKICIGNKNIFTITDLKPDTQYYFDVFAVNTGTNMSTAYVGTFARTKEEAKQKTVELKDGKVTDVFVKRKGSKFLRFAPVSSHQRVTLFVHACLDAVQVQVRRDGKLVLSQNVEGVRQFQ----LRGK---PKAKYLIRLRGSRKGASTLKVLASTRAGGKQPFPALPEDTR-IKAFDKLRTCSSVTVAWLGTQERNKYCVYRREVSESYGEEHRRREQNQCSGPESRRKSEKVLCKYFYSANLQK---AVTTETITGLEAGKSYLLDVYVVGHSGHSVKYQSKLVKTRKYC---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W192-1", "uniprot_id": "NDNF_DROME", "id": "Q9W192-1", "name": "Protein NDNF", "aln": "MQRSTMLPGVELLLLFLLSTSLHAEISHLPMASNRIILDSTELLQNPLIQDAGVPAARATPLPPQKCPSLQRYRKMLKDFDDLEDLYVDVPVHIALAERQRKRFVLNLNDSTPLTIRFSAPVG--RKMYYNQTGNPLRPAAVAPGPGVAVGSLVLPCALRGQYDLFVLARHSGALKVDALAEHPQHDWPLLNATHRIAIRTQNRVR--KREMIVKWERSKFDFHVMHYCLVIQRLSMDTPRMIFTNFCQAVSAYTDQQPMTPS----CAAGGPLEGIWGAPPQRERRLNPRQNV---HIVCTGKRRQQLLRRLLPRSSYHLDLFGIHQGRQNLTLRLASSQVNFNRTQPLALKQQALMQLKIGGQHGKQVYSFKVPQTTRQLGEPFMRHLLIPCSGSEIRVKLLRQRSEVGKTEAFYSPTYIRQKGVLPGERYLMRFEPSNDDEALRAQKVMVALSSEALFRDLPELPQNTTVFNVRTRCSRATIAWNGSPDERELSYCIIVFNLPQRNRSVVDFTNYCMDFVPKRVMQYRYFEWMTCRERQQSPDNIETETILNLMPGSSYLVYVTANLSMGKPLPYQALTLHMASQCLDGSHESFY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: * : :: : * *. : :..:: *.. :. .*:: : . : . : . : :::* * . . .: * : . . :. .** :. :..*. ::. ::.:: : .. *. .*: * . :. * . . . : * : :.:. * . ::. * . *: .: ...: . : . : * : :* : :* *.:. : * * :.*::*:* :: . : * :.: . :.:: ::: : .: :: : .* :::* *:: : . . . * * .:* . * :* * * :**:*:. .... : . . : * **: .: ..*: ** .*:** *: :..: . .. : * * . :: : ::: . : *: : **** .* .*.***: * . *:.: **: :: . * ", "identical_positions": 70, "similar_positions": 188, "identity": "11.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2074", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14671-1", "uniprot_id": "PUM1_HUMAN", "id": "Q14671-1", "name": "Pumilio homolog 1", "aln": "MSVACVLKRKAVLWQDSFSPHLKHHPQEPANPNMPVVLTSGTGSQAQPQPAANQALAAGTHSSPVPGSIGVAGRSQDDAMVDYFFQRQHGEQLGGGGSGGGGYNNSKHRWPTGDNIHAEHQVRSMDELNHDFQALALEGRAMGEQLLPGKKFWETDESSKDGPKGIFLGDQWRDSAWGTSDHSVSQPIMVQRRPGQSFHVNSEVNSVLSPRSESGGLGVSMVEYVLSSSPGD---SCLRKGGFGPRDADSDENDK-GEKKNKGTFDGDKLGDLKEEGDVMDKTNGLPVQNGIDADVKDFSRTPGNCQNSANEVDLLGPNQNGSEGLAQLTSTNGAKPVEDFSNMESQSVPLDPMEHVGMEPLQFDYSGTQVPVDSAAATVGLFDYNSQQQLFQRPNALAVQQLTAAQQQQYALAAAHQPHIG-LAPAAFVPNPYIISAAPPGTDPYTAGLAAAATLGPAVVPHQYYGVTPWGVYPASLFQQQAAAAAAATNSANQQTTPQAQQGQQQVLRGGASQRPLTPNQNQQGQQTDPLVAAAAVNSALAFGQGLAAGMPGYPVLAPAAYYDQTGALVVNAGARNGLGAPVRLVAPAPVIISSSAAQAAVAAAAASANGAAGGLAGTTNGPFRPLGTQQPQPQPQQQPNNNLASSSFYGNNSLNSNSQSSSLFSQGSAQPANTSLGFGS--SSSLGATLGSALGGFGTAVANSNTGSGSRRDSLTGSSDLYKRTSSSLTPIGH-SFYNGLSFSSSPGPVGMPLPSQGPGHSQTPPPSLSSHGSSSSLNLGGLTNGSGRYISAAPGAEAKYRSASSASSLFSPSSTLFSSSRLRYGMSDVMPSGRSRLLEDFRNNRYPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATPAERQLVFNEILQAAYQLMVDVFGNYVIQKFFEFGSLEQKLALAERIRGHVLSLALQMYGCRVIQKALEFIPSDQQ--NEMVRELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHCLPDQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVAEIRGNVLVLSQHKFASNVVEKCVTHASRTERAVLIDEVCTMNDGPHSALYTMMKDQYANYVVQKMIDVAEPGQRKIVMHKIRPHIATLRKYTYGKHILAKLEKYYMKNGVDLGPICGPPNGII", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80U78-1", "uniprot_id": "PUM1_MOUSE", "id": "Q80U78-1", "name": "Pumilio homolog 1", "aln": "MSVACVLKRKAVLWQDSFSPHLKHHPQEPANPNMPVVLTSGTGSQAQPQPAANQALAAGTHSSPVPGSIGVAGRSQDDAMVDYFFQRQHGEQLGGGGSGGGGYNTSKHRWPTGDNIHAEHQVRSMDELNHDFQALALEGRAMGEQLLPGKKFWETDESSKDGPKGIFLGDQWRDSAWGTSDHSVSQPIMVQRRPGQSFHVNSEVNSVLSPRSESGGLGVSMVEYVLSSSPGD---SCLRKGGFGPRDADSDENDK-GEKKNKGTFDGDKLGDLKEEGDVMDKTNGLPVQNGIDADVKDFSRTPGNCQNSANEVDLLGPNQNGSEGLAQLTSTNGAKPVEDFSNMESQSVPLDPMEHVGMEPLQFDYSGTQVPVDSAAATVGLFDYNSQQQLFQRPNALAVQQLTAAQQQQYALAAAHQPHIAGLAPAAFVPNPYIISAAPPGTDPYTAGLAAAATLGPAVVPHQYYGVTPWGVYPASLFQQQAAAAAAATNSATQQSAPQAQQGQQQVLRGGASQRPLTPNQNQQGQQTDPLVAAAAVNSALAFGQGLAAGMPGYPVLAPAAYYDQTGALVVNAGARNGLGAPVRLVAPAPVIISSSAAQAAVAAAAASANGAAGGLAGTTNGPFRPLGTQQPQPQPQQQPSNNLASSSFYGNNSLSSNSQSSSLFSQGSAQPANTSLGFGS--SSSLGATLGSALGGFGTAVANSNTGSGSRRDSLTGSSDLYKRTSSSLAPIGH-SFYSSLSYSSSPGPVGMPLPSQGPGHSQTPPPSLSSHGSSSSLNLGGLTNGSGRYISAAPGAEAKYRSASSASSLFSPSSTLFSSSRLRYGMSDVMPSGRSRLLEDFRNNRYPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATAAERQLVFNEILQAAYQLMVDVFGNYVIQKFFEFGSHEQKLALAERIRGHVLSLALQMYGCRVIQKALEFIPSDQQVINEMVRELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHCLPDQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVAEIRGNVLVLSQHKFASNVVEKCVTHASRTERAVLIDEVCTMNDGPHSALYTMMKDQYANYVVQKMIDVAEPGQRKIVMHKIRPHIATLRKYTYGKHILAKLEKYYMKNGVDLGPICGPPNGII", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IWL6-1", "uniprot_id": "A0A0R4IWL6_DANRE", "id": "A0A0R4IWL6-1", "name": "Pumilio homolog 1", "aln": "MSVACVLKRKAVLWQDSFSPHLRLPPPDRPLPSMPVVLSAAG---HTPQPGPSPQAPAPTQG---------AGRSQDDAMVDYFFQRQHGDQP--------GYNNCKHRWPTGDNIHADNQVRSMDELNHDFQALALEGRAMGEQLLTGKKFWETDDSGKDGPKGIFL-DQWRDSAWGASDHSVSQPIMVQRRPGQGFHGVGEAGSVLSPRSESGGLGVSMVEYVLSSSPAEKMDSCLRKGAYGPRDSEADDPEKRVEQKPKTTFDPERKELKETEPDVLDNPNGLPNQNGLDVDVKDFSRTPGNCPPTGQEVELGGPEMVGG---------AGPKPAEEFSNVETQNVTLDPMESVSMETLQFEYPGGQLPLDSTAATVGLFDYNSPQQLFQRPNALAVQQLTAAQQQQYALAAAQQPHIG-LAPAAFVPNPYIISAAPPGTDPYAAGLAAAATLGPAVMPPQYYGVTPWGVYPANLFQQQAATP---SNSANQQSAAQNQQNQQQVMRAGGNQRPLTPSQGQQGQQTEQLVAAAAVNSALAFGQGLAAGVPGYPVLAPAAYYDQTGALVVNTGAR---GGPVRLMAPASVIISPS---AAVAAAAASAGGANAGLGGGASGAFRALSSQQ---APGQQGSGALGGSSFYGSGSPSSSSQSSSLFSQGSAQPGNTSLGFNANPTSSLGATLGAALGGFGTAVANSSS-SGSRRDSLTGSSDLYKRTASSLTPIGHGAFYNGLSFSSSPGPVGMPLPNQGPSHSLTPPPSLSTHGSSSSLNLGGLTNGSGRFISAAPGAEAKYRSATTGSSLFSPSSQLFPSSRLRYGMSDVMPSGRSRLLEDFRNNRYPNLQLREIAGHVMEFSQDQHGSRFIQLKLERASPAERQLVFNEILQAAYQLMVDVFGNYVIQKFFEFGSLDQKLALAERIRGHVLSLALQMYGCRVIQKALEFIPSDQQVINEMVRELDGHVLKCVKDQNGNHVVQKCIECVQPHALQFIIDAFKGQVFALSTHPYGCRVIQRILEHCLPEQTLSILEEIHQHTEQLVQDQYGNYVIQHVLEHGRAEDKSKIVSEIRGNVLGLSQHKFASNVVEKCVTHSLRAERAMLIDEVCSMADGPHSALYTMMKDQYANYVVQKMIDVAEPTQRKIVMHKIRPHIATLRKYTYGKHILAKLEKYYMKNGVDLGPLCAPPNGIM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********************: * : . *.*****::. ***... .* *:. *******************:* ***..************::***************************.********:*.********* *********:*****************.** .*..*************************.: ******.:****:::*: :* *:* * *** :: : * **:*:.**** ***:*.************ :.:**:* **: *. *.**.*:***:*:*.*.***** *.**.***:*.* *:*:**:*********** ****************************:****. ***********************:*************:* *************.*******:. :***.**::.* **.****:*.*..******.*.******: ********************:*********************:*** *.****:***.****.* **********.** .**.* :.*.**.*.:** * ** .. *..*****..* .*.**************.******.: :********:************.: ******************:***:**** :**..**:************.***.** *******:******************:**************::.******** **.***************************************:********************:.*********************************** :************************************** *********************************::**********************************:***.****:*************************.*******:******* *****************: *:***:******:* ***************************** ******************************************:*.*****:", "identical_positions": 944, "similar_positions": 146, "identity": "78.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2081", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3KRD5-1", "uniprot_id": "TOM34_RAT", "id": "Q3KRD5-1", "name": "Mitochondrial import receptor subunit TOM34", "aln": "MAPK-VSDSVEQLRAAGN-QNFRNGQYGEASALYERALRLLQARGSADPEEESVLYSNRAACYLKDGNCTDCIKDCTSALALVPFSIKPLLRRASAYEALEKYSLAYVDYKTVLQIDNSVASALEGINRITRALMDSLGP---------------------EWRLKLPPIPVVPVSAQKRWS-------------SLPSENHKETAKSKSKETTATKNRVPSAGDVERARVLKEEGNELVKKGNHKKAIEKYSESLLFSS-LESATYSNRALCHLVLKQYKEAEKDCTEALKLDGKNVKAFYRRAQAYKALKDYKSSLADISSLLQIEPRNGPAHKLRQEVNQNMN---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CYG7-1", "uniprot_id": "TOM34_MOUSE", "id": "Q9CYG7-1", "name": "Mitochondrial import receptor subunit TOM34", "aln": "MAPK-VSDSVEQLRAAGN-QNFRNGQYGEASALYERALRLLQARGSADPEEESVLYSNRAACYLKDGNCTDCIKDCTSALALVPFSIKPLLRRASAYEALEKYALAYVDYKTVLQIDNSVASALEGINRITRALMDSLGP---------------------EWRLKLPPIPVVPVSAQKRWN-------------SLPSDNHKETAKTKSKEATATKSRVPSAGDVERAKALKEEGNDLVKKGNHKKAIEKYSESLLCSS-LESATYSNRALCHLVLKQYKEAVKDCTEALKLDGKNVKAFYRRAQAYKALKDYKSSLSDISSLLQIEPRNGPAQKLRQEVNQNMN---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15785-1", "uniprot_id": "TOM34_HUMAN", "id": "Q15785-1", "name": "Mitochondrial import receptor subunit TOM34", "aln": "MAPK-FPDSVEELRAAGN-ESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMTRALMDSLGP---------------------EWRLKLPSIPLVPVSAQKRWN-------------SLPSENHKEMAKSKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSN-LESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQNLH---------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZM24-1", "uniprot_id": "Q6ZM24_DANRE", "id": "Q6ZM24-1", "name": "", "aln": "MPQKRRTQSWTDLKQAGN-ECFKAGQYGEAVTLYSQAIQQLEKSGQKKTEDLGILYSNRAASYLKDGNCNECIKDCTASLDLVPFGFKALLRRAAAFEALERYRQAYVDYKTVLQIDWNIPAAHDGVNRMTKALTEMDGP---------------------SWREKLPPIPTVPMSVKEKLG-------------QAASP----ASSSQQNNVIDDKKKAPGPDAVKKGRTLKEEGNALVKKGEHKKAMEKYTQSLAQDP-TEVTTYTNRALCYLALKMYKDAIRDCEEALRLDSANIKALYRRAQAYKELKNKKSCIEDLNSVLKIDPNNTAVQKLLQEV-QKMK---------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBA1-1", "uniprot_id": "Q9VBA1_DROME", "id": "Q9VBA1-1", "name": "", "aln": "MEKEKKKSLLERYNIPIHYLDFAHVEKCTNAREMEKIVQILRSGEEGHYPDLQRCAEEKLKALKPDSKLFRYEEQIKQSTDLDKTELKPILDWTDAIKTKDNALNELKKVKQNLNLPSVRKLSKIDLEKESKTEKPKPAPKATSPSNTKNKEARIKSTDYRKWDKYDPDEEILRMDLNEERDQEQREKIISNHSKSVTTDKLQSERDSLYERLQAQLKNLSQLEKEQFAERHRLRGNESFKAKEYENAIEEYNCSIIYDPENAVHAYNNRAVAHLKLKKYFSAISDCQACLQIDPMNIKAHLRMAEAHNAEGKHLESLNVYKKLLDFEPDNAIAKKAVEKLTSMLGEVAPSSATRLIIEEIDPPQLKTSEPKKEAEKSEPTVVKKPEPVVSAKKPPPIKDYDLAELVKPNRMVKSNLVSAAEALGNKMQASKGGAPKKPQSPPMTPKETLLRLPQDNLNNSNKLLIQEI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . . . : * : : :: *. . . : .:: . *.: :: . : * :*.:* : * :: :. . * *:: : .::: ::: .* .* * : :. ::. . . .: .: :. .. . : .. : .** .* ::::*:*:*. *: . :*.***:.:* ** * .* ** .*::* *:** * *:*:: . ..: ..:*.::* * .:* ::: . : ", "identical_positions": 43, "similar_positions": 106, "identity": "9.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2084", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9HCU0-1", "uniprot_id": "CD248_HUMAN", "id": "Q9HCU0-1", "name": "Endosialin", "aln": "---MLLRLLLAWAAAGPTLGQDPWAAEPRAACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVG------AGPASRLLWIGLQRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEAS-------GEHRWLEGSCTLAVDGYLCQFGFEGACPALQDEAGQAGPAVYTTPFHLVSTEFEWLPFGSVAAVQCQAGRGASLLCVKQPEGGVGWSRAGPLCLGTG----CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISCSPAGAMGAQASQDLGDELLDDGEDEEDEDEAWKAFNGGWTEMPGILWMEPTQPPDFALAYRPSFPEDREPQIPYPEPTWPPPLSAPRVPYHSSVLSVTRPVVVSATHPTLPSAHQPPVIPATHPALS----------------RDHQIPVIAANYPDLPSAYQPGILSVSHSAQPPAHQPPMISTKYPELFPAHQSPMFPDTRVAGTQTTTHLPGIPPNHAPLVTTLGAQLPPQAPDALVLRTQATQLPIIPTAQPSLTTTSRSPVSPAHQISVPAATQPAALP-TLLPSQSPTNQTSPISPTHPHSKAPQIPREDGPSPKLALWLPSPAPTAAPTALGEAGLAEHSQRDDRWLLVALLVPTCVFLVVLLALGIVYCTRCGPHAPNKRITDCYRWVIHAGSKSPTEPMPPRGSLTGVQTCRTSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91V98-1", "uniprot_id": "CD248_MOUSE", "id": "Q91V98-1", "name": "Endosialin", "aln": "---MLLRLLLAWVAAVPALGQVPWTPEPRAACGPSSCYALFPRRRTFLEAWRACRELGGNLATPRTPEEAQRVDSLVG------VGPANGLLWIGLQRQARQCQPQRPLRGFIWTTGDQDTAFTNWAQPATEGPCPAQRCAALEAS-------GEHRWLEGSCTLAVDGYLCQFGFEGACPALPLEVGQAGPAVYTTPFNLVSSEFEWLPFGSVAAVQCQAGRGASLLCVKQPSGGVGWSQTGPLCPGTG----CGPDNGGCEHECVEEVDGAVSCRCSEGFRLAADGHSCE--DPCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISCSPAGAMGAQASQDLRDELLDDGEEGEDEEEPWEDFDGTWTEEQGILWLAPTHPPDFGLPYRPNFPQDGEPQRLHLEPTWPPPLSAPRGPYHSSVVSATRPMVISATRPTLPSAHKTSVISATRPPLSPVHPPAMAPATPPAVFSEHQIPKIKANYPDLPFGHKPGITSATHPARSPPYQPPIISTNYPQVFPPHQAPMSPDT-----HTITYLPPVPPHLDPGDTTSKAHQHPLLPDAPGIRTQAPQLSVS-ALQPPLPTNSRS---SVHETPVPAANQPPAFPSSPLPPQRPTNQTSSISPTHSYSRAPLVPREGVPSPKSVPQLPSVPSTAAPTALAESGLAGQSQRDDRWLLVALLVPTCVFLVVLLALGIVYCTRCGSHAPNKRITDCYRWVTHAGNKSSTEPMPPRGSLTGVQTCRTSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IKQ6-1", "uniprot_id": "A0A0R4IKQ6_DANRE", "id": "A0A0R4IKQ6-1", "name": "", "aln": "MGCPVLCVILLSSLLCLYGVQAQDLRERDALCNEDGCYVLYFQRKIFLDAWRSCKEQDGNLATIRHPKDAETVRELFSNVELRQHHRGKANIWIGLQRQPRQCSPTRPLRGFSWVTGDQDTQFTNWLQDDSASTCSSPRCVVMPYSTVAADRGDNLKWKDGPCSISVDGYLCKYNFRGMCTAIASEG--GGNILYSTPFNLLSTILTHVPYGSVATVPCLAKDDQSVLCTQKEDGTVFWNRDPPFCTETSKTSWCDQDNGGCHHFCIETG-LHYYCDCNEGFLLAEDGVSCFPSDPCNGAPCEFECLP-VMDGYRCACPDGYMLAPDE-RGCVDVDECLQS-PCEHICVNSPGTFECRCRDGYQQDEDGACEDVDECINNPCEHACENTMGSHICHCHYGFAPLQEDQSHCHDVDECQIEG--TCEQMCINYDGGFECYCEEGYNLQPDHYS---CRPLGEDTTTVFDPSSTPIWGPEHSLYPWHFS----------------------------HGPDLKTPQDWQTKLPKVETVSTDSLLTSEEEP--ETTTLTESFPEVTNIDGYLHPEEPR----HNAFFPPTTPKPTPDYYEDESTTVPTELPSSTTLGGAWNWLWFSSTQTKPEIQETAN--------------NPLDFP----------GDYDPYDPDHFNDQFDNEYTTYGPEQQTSTLFPMQSRGVGENDILNEDSSSEKSHGTSWLLVGLLVPLCIFIVVMVVLGIIYCTRYTVKPQNKNTNDCYHWIAGAGDKAAAD-ISGSGTKSHV-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* ::* * * * *. ..**.*: :*: **:***:*:* .*:*** * *::*: * .*.. .. :*******.***. ****** *.****** **** * : ..*.: **..: * .: :* :*.*:::******::.*.* *.*: * .* :*:***:*:*: : :*:****:* * * . *:**.:: .* * *.: *:* *. *. *****.* *:* * *.*** ** ** ** *** **** :* * :** * * *: * *: : ***.*** : *:::*** * *** * :*:: : ** . . .:. ..: : : .. . . . : :. : :: : * .* * :. . * ::*.. : . : .. :. * .. :: ..** . * . . * :.. :: .:*:: . :. :. . * * : . *.: : * . : . : . :* :* .: .. .* * .: *. : :* . .. . : : . : ...:. ****.**** *:*:**::.***:**** :. **. .***:*: **.*:.:: :. *: : * ", "identical_positions": 201, "similar_positions": 205, "identity": "25.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-210", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q498T2-1", "uniprot_id": "CHTOP_RAT", "id": "Q498T2-1", "name": "Chromatin target of PRMT1 protein", "aln": "---------------------------------------------------------------------------MAAQSAP----KVVLKSTTKMSLNERFTNMLKNKQPMPVNIWASMQQQQQLASARNRRLAQQMENRPSVQAALKLKQ-SLKQRLGKSNIQARLGRPIGALARGAIGGRSLPIIQRGLPRGGLRGGRATRTLLRGGMSLRGQNLLRGGRAVAPRMGLRRGGVRGRGGPGRGGLGRGAMGRGGIGGRGRGMIGRGRGGFGGRGRGRGRGRGALTRPVLTKEQLDNQLDAYMSKTKGHLDAELDAYMAQTDPETND", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CY57-1", "uniprot_id": "CHTOP_MOUSE", "id": "Q9CY57-1", "name": "Chromatin target of PRMT1 protein", "aln": "---------------------------------------------------------------------------MAAQSAP----KVVLKSTTKMSLNERFTNMLKNKQPMPVNIRASMQQQQQLASARNRRLAQQMENRPSVQAALKLKQKSLKQRLGKSNIQARLGRPIGALARGAIGGRGLPIIQRGLPRGGLRGGRATRTLLRGGMSLRGQNLLRGGRAVAPRMGLRRGGVRGRGGPGRGGLGRGAMGRGGIGGRGRGMIGRGRGGFGGRGRGRGRGRGALTRPVLTKEQLDNQLDAYMSKTKGHLDAELDAYMAQTDPETND", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3Y2-1", "uniprot_id": "CHTOP_HUMAN", "id": "Q9Y3Y2-1", "name": "Chromatin target of PRMT1 protein", "aln": "---------------------------------------------------------------------------MAAQSAP----KVVLKSTTKMSLNERFTNMLKNKQPTPVNIRASMQQQQQLASARNRRLAQQMENRPSVQAALKLKQ-SLKQRLGKSNIQARLGRPIGALARGAIGGRGLPIIQRGLPRGGLRGGRATRTLLRGGMSLRGQNLLRGGRAVAPRMGLRRGGVRGRGGPGRGGLGRGAMGRGGIGGRGRGMIGRGRGGFGGRGRGRGRGRGALARPVLTKEQLDNQLDAYMSKTKGHLDAELDAYMAQTDPETND", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0RDD7-1", "uniprot_id": "M0RDD7_RAT", "id": "M0RDD7-1", "name": "", "aln": "---------------------------------------------------------------------------MAAQSAP----KVVLKSTTKMSLNERFTNMLKNKQPMPVNIRASMQQQQQLASARNRRLAQQMENRPSVQAALKLKQKSLKQRLGKSNIQARLGRPIGALARGAIGGRSLPIIQRGLPRGGLRGGRATRTLLRGGMSLRG----------------------------------------------RGMIGRGRGGFGGRGRGRGRGRGALTRPVLTKEQLDNQLDAYMSKTKGHLDAELDAYMAQTDPETND", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9PAT6-1", "uniprot_id": "A0A8M9PAT6_DANRE", "id": "A0A8M9PAT6-1", "name": "", "aln": "MKDGLCAIHIVCPLSCKNTLSLQRYFLLHLCFSLSFCLQKKVPSPYLDVTCCSTFSQGVSYRTAYRVMVLVVSGWVAGHPCSPGLTHRVVSRTSQLVDGGLFTNMLKNKQPTVSSIRATMQQQH-MASAHNRLLAQQMENRPSVQAALHHKQ-SLKQRLGKSNIQARLGRPIGSLMQG--GGRGR----------GLRG-RARGGTMRGALSFRGAGQMRG-RGGPGRMGFRRGMRHRGGAPGRGALGGRGAARGMPGGRGRGGM-RGRGGFAGRGRGRGRGRGAG-RPIVTREQLDNQLDAYMSKTKGHLDAELDAYMAQADPESME", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.:... : *:. *::: . ********** .* *:****: :***:** ***************: ** ********************:* :* ***. **** ** :**.:*:** ** : ******.************ **::*:****************************:***: :", "identical_positions": 131, "similar_positions": 34, "identity": "39.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2100", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9V421-1", "uniprot_id": "Q9V421_DROME", "id": "Q9V421-1", "name": "Metalloendopeptidase", "aln": "-------------MCYYSILLLLLVVVNVAWAAPSIR--------------------------------------------IETDPELTAGYIEGDMVPS-----------GSSRNIWRNETYRWPNR-----IIYYHINSYIDEEHRNHIVSAIQKIESISCLTFKEATTDQ---KYYVNVTSEEGGCFSYIGYLNRVQQLNLQNNEIGVGCFR-LYTIVHEFLHALGFFHQQSAADRDDYVQIVEENITEGMEFNFDKYTEETVNDFGEKYDYGSVMHYGPYAFSKN-GERTILALEEG--KEDVIGQRLELSETDIRKLNAIYKCPTVKE------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V3M3-1", "uniprot_id": "Q9V3M3_DROME", "id": "Q9V3M3-1", "name": "Metalloendopeptidase", "aln": "-------------MKTWALTLVVIFLASSCSAAPTTQNR------------------------------------------IETDPELTAGYIEGDMVPS-----------PEGRNGLRNETFRWPNR-----IVYYYINRDIDTEHRNHILRGIRIIEQSSCLVFKEATTDQ---EYYVNVTSEAGGCYSYVGYRNRVQQLNLQTYALDTGCFR-LGTIVHEFLHALGFYHQQSTWNRDDYVRIAEENITEGTEGNFNKYDNETVEDYGEPYDYSSVLHYTAYAFSKN-GEMTIVPLQEG--AEELMGQRLQMTQSDINKLNVMYKCPRQV-------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V445-1", "uniprot_id": "Q9V445_DROME", "id": "Q9V445-1", "name": "Metalloendopeptidase", "aln": "-------------MSRSGIIYVLLLQVVLNSGKPLPAG--------------------------------------------VYDPEEAGGFVEGDMMLTEEQQRNLEQGAPKARNGLINTEKRWPGN-----VVVYRISDDFDTAHKKAIQTGIDTLELHTCLRFREATDED---KAYLTVTAKSGGCYTAVGYQGAPQEMNLEIYPLGEGCFR-PGTILHEFMHALGFYHQQSSSIRDDFINVIYENIVPGKEFNFQKYADTVVTDFEVGYDYDSCLHYRPGAFSIN-GEDTIVPLDSS----AVIGQRVGLSSKDIDKINIMYKCPILL-------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCN5-1", "uniprot_id": "Q9VCN5_DROME", "id": "Q9VCN5-1", "name": "Metalloendopeptidase", "aln": "MSLKVFLVLALALSSCQALPYVSYDDVDDTEVIELPGNGIEEIPPTLGKDIIDLTPLGTALFGKPDEELTANRVGNFSADADEMNPEELGSYLEGDMLVPQT-----DLIMK---NGLPTQSSRWPNG-----VVPYEIRGNFNARDMATIENAIGEYHRRTCIRFVKRSSE----RDYISIRGDNSGCWSSVGRVGGKQEVNLQS----PGCLSRPGTAMHELMHALGFLHEQNRMERDGYVAIQYNNVQSSAMNNFEK-AARTEA-FGVPYDYGSVMHYSKNAFSIN-GQPTILAMQAN--GADKMGQRNGFSDYDIQKLNRMYDCGTVNAVPVAPGLPAPAPAPGAPAGSGNPIVDSFIGGLISGLGLGDEKKETSS-------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VC98-1", "uniprot_id": "Q9VC98_DROME", "id": "Q9VC98-1", "name": "Metalloendopeptidase", "aln": "--------MGKSQNNTGSLLLLIILGISLGDSMPL-----EDMD---SQEMIDLTDLGDTLFGNPDVETTGALVEALGVES-PLNPEELGTYHEGDILIPLSYR---DARFNGTRNGILALSSRWPGG-----VVPYEIKGPFTSQELGNINHAFKEYHTKTCVRFKPRTTE----KDYISIGSGKSGCWSSIGRLGGRQEVNLQS----PNCLRTYGTPIHELMHALGFFHEQNRHERDSYVRVMKDNIKPEMMVNFEKSSSRTQYGFGVEYDYGSVMHYSPTSFTRN-GQPTLKALRATS-DASQMGQRKGFSAGDVRKINAMYKCKV---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D3ZX09-1", "uniprot_id": "D3ZX09_RAT", "id": "D3ZX09-1", "name": "Metalloendopeptidase", "aln": "------MGGVGSLGSLWPWMLTLLSLTGLILGAPSASRCSGVCS----------TSVPEGFTPEGSRVSQDKDIPAINQGLISEETPESSFLVEGDIIRPS----------PFRLLSVTNN--KWPKGVDGIVEIPFLLSSKYDEPSRQVIMEAFAEFERFTCIRFVAYRGQ----RDFVSILP-MAGCFSGVGRSGGMQVVSLAPT----CLQKGRGIVLHELMHVLGFWHEHSRADRDRYIRVNWNEILPGFEINFIKSRNSNML---APYDYSSVMHYGRFAFSWR-GQPTIIPLWTS---SVHIGQRWNLSTSDITRVCRLYSCSPSVPDSHGRGFEAPSDGRSPTPASISHLQRLLEALSEESRSSAPSGSGTGGQGIIAGFVDSQQGWEHPAQSTFSVGALARSPQMLAAASKSRPGAGADSISLEQFQPAQAPAVPPVSFPDARDKPTPIQDAFARLALLPGGCAPGSHIREVPRD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6HA09-1", "uniprot_id": "ASTL_MOUSE", "id": "Q6HA09-1", "name": "Astacin-like metalloendopeptidase", "aln": "---------MGIMGSLWPWILTMLSLLGLSMGAPSASRCSGVCS----------TSVPEGFTPEGSPVFQDKDIPAINQGLISEETPESSFLVEGDIIRPS----------PFRLLSVTNN--KWPKGVGGFVEIPFLLSRKYDELSRRVIMDAFAEFERFTCIRFVAYHGQ----RDFVSILP-MAGCFSGVGRSGGMQVVSLAPT----CLRKGRGIVLHELMHVLGFWHEHSRADRDRYIQVNWNEILPGFEINFIKSRSTNML---VPYDYSSVMHYGRFAFSWR-GQPTIIPLWTS---SVHIGQRWNLSTSDITRVCRLYNCSRSVPDSHGRGFEAQSDGSSLTPASISRLQRLLEALSEESGSSAPSGSRTGGQ-SIAGLGNSQQGWEHPPQSTFSVGALARPPQMLADASKSGPGAGADSLSLEQFQLAQAPTVPLALFPEARDKPAPIQDAFERLAPLPGGCAPGSHIREVPRD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6HA08-1", "uniprot_id": "ASTL_HUMAN", "id": "Q6HA08-1", "name": "Astacin-like metalloendopeptidase", "aln": "---------MEGVGGLWPWVLGLLSLPGVILGAPLASSCAGACG----------TSFPDGLTPEGTQASGDKDIPAINQGLILEETPESSFLIEGDIIRPS----------PFRLLSATSN--KWPMGGSGVVEVPFLLSSKYDEPSRQVILEALAEFERSTCIRFVTYQDQ----RDFISIIP-MYGCFSSVGRSGGMQVVSLAPT----CLQKGRGIVLHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSQSSNML---TPYDYSSVMHYGRLAFSRR-GLPTITPLWAP---SVHIGQRWNLSASDITRVLKLYGCSPSGPRPRGRGSHAHSTGRSPAPASLS-LQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLSAEASARQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGS----PALPGGCVPRNHFKGMSED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LW01-1", "uniprot_id": "HE12_DANRE", "id": "Q1LW01-1", "name": "Hatching enzyme 1.2", "aln": "---------MDIRASLS----ILLLLFGLSQASPLR-------------------EFEAIFVSEPETVDITTQILETNKG-------SSEVLFEGDVVLPK----------NRNALICEDKSCFWKKNANNIVEVPYVVSGEFSINDKSVIANAISIFHAQTCIRFVPRSIQ----ADYLSIEN-KDGCYSAIGRTGGKQVVSLNRKG---CVYSG--IAQHELNHALGFYHEQSRSDRDQYVRINWNNISPGMAYNFLKQKTNNQN---TPYDYGSLMHYGKTAFAIQPGLETITPIPDE---NVQIGQRQGLSKIDILRINKLYGC-----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFD6-1", "uniprot_id": "Q9VFD6_DROME", "id": "Q9VFD6-1", "name": "Metalloendopeptidase", "aln": "----------MFLKAVRYLLLAGIFAPNLVASEGIES----------------------------------------------YENYYNEIHIDDEQAEAK------------TRNALTSPLQRWPGN-----KILYRISTDYSEQEVANVRTAMSSFGEQTCVQFEEIEGAPPAGKRYVSFKKSPNMCGTRVGYQPLSFGPHEVVLN--EKCLTMPAVIQHETLHLLGLFHEQSRPDRDEYVQIDYDNIPRKYWSQFMAMDQTTTFN--VPYDYESVMHYSKNAFAKDPSKPTIRALIGGKAVEREMGQVRGPSEGDWTKIRLMYKC-----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: . * : : : : .: :*: * ::.. * : :* ** * **: *::. ** :: : ::: :* *** * :** :*: . *: .: :** : * :: :* * ", "identical_positions": 27, "similar_positions": 41, "identity": "5.59%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2140", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9Q5F9-1", "uniprot_id": "SETD2_MOUSE", "id": "E9Q5F9-1", "name": "Histone-lysine N-methyltransferase SETD2", "aln": "MKPLPSQQPPPKMGDFYDPEHPTPEEEENEAKIENVQKTGFIKGPVFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSFTKKTLQNRFLTALSNEKQSDSPNSPAPPLQVDSNPKVKMDAGDTFPATEESSPPKSRVELGRIHFKKHLLHVTSRPQLAASTTAASPLPPTTQLPAVLAES-MIDSPPSSPPPPPPPPQASSPSPPAQISEPVALPQPPATALMTSPPGPLPGDVAVRAQKESPVKSGPEVLEVDTKQDIVSNSLEEHTVQTLKEQADHLLQKEDSHIGKEEEVSDGSKISLSSKKASSKKKSSQFEGTFLGSESDEDSVRTSSSQRSHDLKSSTSIDKERDFKKSSAPSKSEDLGKSSRSKTERDDRYCSYSKLERDTRYVSSR-CRSERDRRRSRSRSRSDRASRTSLSYSRSERS-----------HYYDSERRYHRSSPYRERTRYSRPYTDNRARESSDSEDEYKKTYPRRTSAHS--YRDLRTSSSYSKFDRDCKTETSYLEMERRGKYTSKLERESKRTSEHETIKRCCSPPNELGFRRGSSYSKHDNSTSRYKSALSKSISKNDKFKNSFCCTELNEENKQSHSFSLQTPCSKGSELRTINKISEREKTGSPTPSNQLNDSPTFKKLDESPVLKPEFIGHDGRES-IKELE-LSKVKNDQLRNFCSIELNVNGSPETEADVATFCTSKTDAISMTSDDSVTGSEVSPLIKACMLSSNGFQNVGRCRERDSDDTCRQHNTSKSPFREMEPLLSPHHDKLMSLPVKTIDYPKTLIKEPVDKRHSCCKTKDSDIYCSPNE------NPEAENAEPSAMTISSHSFVNVHLESKTVICDNREPTDRHSENTCDEYKQSIGSTSSASHNHFDGLYEPIGSSGISS-LQSPPSGIR--------CEENTSPTLDAVE-SKKGIDFLKYARKET--DVGSALPDSGKGFS-WENRHNNVLSGQSLQEAQEEGNSILHERRGRPEIPLDEE-QRGHTHISDDSEVVFP-YDLNLTMEDSDGITYTLKCDSSGNAPEIVSTVHEDYSGSSASSSDESDSEDTESDDSSIPRNRLQSVVVVPKNSTLPMEETSPCSSRSSQSYKHYSDRWEDG-LETRRHAYEEEYE---SKGCSQTEKYFLHKGTERSAESCYSQFGRK-ADNHLPDIAHAQSDGVDSTSQTDSRSDHLGHLNPEDTLRAKTSRPQ--ELPVYSDDFEDLPNKS-RQQMIFSNRPDSSRLGKTELSFSSSCDISRMDGLHSSEELRNLGWDFSQQERPTTTYQQPDSSYGTCGTHKYQQSTEHYGGTHNYWQGNGYWDPRSAGRPPGTGLAYDRIQGQVPDSLTDDREEEEHWDQRSGSHFSSPSNKFFFHQ-KDKGSVQAPEISSNSIKDALVMNERKDFSKNFEKNDIKERGPPKKRRQELESDSESDGELQARKK-----VRVEMEQGESSVPQHSELMGPSCAMDDFRDPQRWKEFAKLGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEVACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRKKD------SVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLKLIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRE---SNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPQLSEGDGYSSENTSRAHTPLNTPD-PSAKPSTEMDTDTPKKLIFRRLKIISENSMDSAVSDVTSELECKDGK-EDLDQLET------------VTVE------------------------------------EDEELQSQQLLPQQLC--ESKVESEATIEVSKLP-----------------------------------------------------------------TSEPEADTETE--------------PKDSNGTKLEET---------------------------------------------------------------------------------------------------------------------------------------IAEETPSQDEEEGVSDVESERSQEPPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKESTVAERGRDAAAFRDQT-APKTPNRSRERDPDKQS-------------------------QNKEKRKRRGSLSP-PSSAYERGTKRPDDRYDTPTS-KKKVRIKD-RNKLSTEERRKLFEQEVAQREAQKQQQQ-------------------------------------MQNLGMTSPLPFDSLGYNASHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCS-PAPYDHAQP-----LVGHSTESLAAPPSVPVVPHVAASVEVSS-SQYVAQNESVVHQDSNVPVMPVQAPG-----PVQGQNYNVWESN-QQSVSVQ----QQYSP-AQSQTTIYYQGQTCSTVYSVTSPYSQTTPPIVQSYAQPSLQYIQGQQIFTAHPQGVVVQPTAAVTSIVAPGQPQSLQPPEMVVTNNLLDLPPPSPPKPKTIVLPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPMKTSKKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYW2-1", "uniprot_id": "SETD2_HUMAN", "id": "Q9BYW2-1", "name": "Histone-lysine N-methyltransferase SETD2", "aln": "MKQLQPQ-PPPKMGDFYDPEHPTPEEEENEAKIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTHAAPLPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAP-VPLPVDVAVRSLKEPPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKDEEIPDSSKISLSCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSR-CRSERERRRSRSHSRSERGSRTNLSYSRSERS-----------HYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRTSSHSSSYRDLRTSS-YSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKRCCSPPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQTPCSKGSELRMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDS-IKELDSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSPLVKACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSKTVVKEPVDTRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESKPVICDSRNLTD-HSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNNGLSGKCLQEAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSVVVVPKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTDKFFLHKGTEKNPEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKAKIPSRQQEELPIYSSDFEDVPNKS-WQQTTFQNRPDS-RLGKTELSFSSSCEIPHVDGLHSSEELRNLGWDFSQ-EKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPR-SGRPPGTGVVYDRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQAPEISSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKK-----VRVEVEQGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRKKD------SVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRE---SNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPD-PSTKLSTEADTDTPKKLMFRRLKIISENSMDSAISDATSELEGKDGK-EDLDQLEN------------VPVE------------------------------------EEEELQSQQLLPQQLP--ECKVDSETNIEASKLP-----------------------------------------------------------------TSEPEADAEIE--------------PKESNGTKLEEP---------------------------------------------------------------------------------------------------------------------------------------INEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENTTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQT-------------------------QNKEKRKRRSSLSP-PSSAYERGTKRPDDRYDTPTS-KKKVRIKD-RNKLSTEERRKLFEQEVAQREAQKQQQQ-------------------------------------MQNLGMTSPLPYDSLGYNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCS-PAPYDHAQP-----LVGHSTEPLSAPPPVPVVPHVAAPVEVSS-SQYVAQSDGVVHQDSSVAVLPVPAPG-----PVQGQNYSVWDSN-QQSVSVQ----QQYSP-AQSQATIYYQGQTCPTVYGVTSPYSQTTPPIVQSYAQPSLQYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNNLLDLPPPSPPKPKTIVLPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPMKASKKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B685-1", "uniprot_id": "A0ACD6B685_DANRE", "id": "A0ACD6B685-1", "name": "[histone H3]-lysine(36) N-trimethyltransferase", "aln": "------------MDALLNPELR-EDVKDCSIKVENFPKQVIFKGLAPRVVLTNHLLMKGNKTKVNLEEQGRQKVSFSLTQTKKPRQNVFLPPPSPEKSASEHSSTSQAGPVP----VSVQAGQTYETKN----------------------VDTNTPAVGETQTAPTVSFSLRSRHVLGKMHFKKQILSSTVVG---DKSTVSTASAEISEPVVPSDK--------------ITSSAKVETENSLQQSHKNSVVDGSSEKVS-----KEENPQEKIASCLKGPDSSHIGKED--TDSSIISEHEESRKSKQCS---DSKLAGLETDGQSTRTSSSQKSNDRRNKTKSESHSNEVKRSSNSKT-ELDK-SRTDRKDEEKGIRHSKSDRDSRHMSSRSSRSDRDRRRTKSRSRSRSRGSRTSSYSRSERSRSERQSRTDRSHYHESERRFHRSSPHRER-RSSRSRTDGRSRDSSDSEDDHRRTRTRGSDSSR--------SSTYSSSQKDSKSST-----HSRSHRDSKPTDCSRSSESDKRAQHSKSESN----RRSSS----EIDAVHKKSSARTKLEVNDKISNSNLTTSSRTSEKKIHKTSSDSDEEHRRKRQSQGSDRSPRSGTSSSRKNDLVDHNSFNIGTGTERQSTDRLNTNAKDSQLVFVTVTSQKESSNIDDQCTPPKSKNSSQQMHEATHKVNLCETN---KKAEHQPSNQDLSSLEKCTNVPES-KKTTERLTESISITSGKLEVRSPTEVDEPGMKVT----VPIQSEVLTVGQTESICVGPAPSEHTMGSLTDSLSVKELPPEGSLILNTKSDESSLIISQISTPVTLTVQPCEK------------DSEQNIGSPEQPNTGISKKDASAKKSRWDIVG--QVTSEYQSP--------------AKLVNPDVKKVMLAQK-IEFSDTTPDNCSQKLDPEVPS--------EKSVEVHARDTTAAESHQEISSFTSN--------------FGTKGTHDELQKTVEIPQSTSALVVSDFQPSKEKVNVDKTKPEIQDPDSLNHDGKCHSDDSESEESDSDSDDGRVSLKRLHSVVVVPKNSTIALETNDKAEPAPASS--LFSGNQQTDTHESINKEFPYGFN---NQSTLKESSAALYKGSAQAACQSPNVKGVS---------YQSQSNMVDSTSHLEVMSAHVDK-NWSAQERPNISGQIN---QEYVQNFEKTCEKPETDHHQYHGRPDSWNGRKGDFSVG------RGD---------SLVWDFNQSEQPSSTFQQPDSSYSTP------QPLFDSVHREDPWAQPAISKTSRTVNTHVPFQYHDLVHQIHPDSLTNDHDD----DREGRILGIKQASLLSAGLPGPSPFVQAPEISSNCSFTTESQN-ISEAPRDDNQKPHRGRGPPKKRRQEFESESDNEAEAGLSKRECFDESSRPLKDAKESFHQIQEVQRPLLSLKEFSDPFVWRDKAKQKKMPPYFDLIEENLYLTERKKNKSHRDIKRMQCECAILSKEERARGILACGEDCLNRLLMIECSSRCLNGAYCSNRRFQMKQHADYEVILTESKGWGLRAAKDLQPNTFVLEYCGEVLDHREFKARVKEYARNKNIHYYFMALKNNEIIDATLKGNCSRFMNHSCEPNCETQKWTVNGQLRIGFFTTKAVTAGTELTFDYQFQRYGKEAQKCFCGAPSCRGLIGGETRVSVRAAGGKKQRERSRKKDTDSALTTLDEELEALQENGEGLCGEKEVISLCRLMVRVETMEQRLTCLKLIQNTQNPLCLKQFLDHHGLSLLWIFMVELSEAKTNSVNNIKLQLEIMKALSVLPISTKNMLEESRVLQFIQRWAQSR-SLSQPAEQDGYSSESTSRAQTPLNTPDGPPAKLATELDGDTPKRAVYRRLKIISENSLDSALSDASKASDGKEEEDEEEEEMEDEPSKLESTTERKIKVESTEAPPVSQAELEVELKQEAPETVEIPRLMPEAVGSEGETLETQEPEEKLLCTPEGQLKDEKTVEETKSDEPSENQTESAAVKEDPLVTDTTSAADISNDVVADAETPVTETQVENASSEQSTSEEDASCSTAEITSAQPAEVIIEGISSDSAAIVIKSTPKESPSVSVKTPPTGSDVVSNGNAPSEAVFAPSEAVAAPLEAAVAPSEAVASFPEAVASLPETVAAPAEAVDEPAEAVADPAEAVADPAEAVADPAEAVAEPAEAVAAPAEAVAAPPEAVAAPPEAVAAPVSADVSALAIVPVPAEGAAVGTPSQDEEEGVSDVESERSQEPQIRASDISDMAARLLDSWKDLKEVYRIPKKSQVEKESNDRSRDRESLMTPRTSSSSRERERERDKERDRDRDRDWEREREWDRDRERDRDGERPTLRSADRKRRRGSTSPLPPPAYER-SRRNDDRYEQSSSSKKKLHTKEARTKLSTEERRKLFEQEVAQREAQKQQQQQLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLQTLAFNPLAYTSSPN-FMNYPPGYPIQTYVDPTNPNAGKVLLPTPPVEPICVTPAAGTFEQPPALDLGIASPSSTTTQAGPASSLAHIPAPLELSSGTQTQFVQPAVPAQDPSVAVLSVPAQAASPQIPSQQGYTTLWDPNTQQAVTVQTQPTQQYSTTSQPQAAIYYQGQPCQTIYSIPAGYPQTNPPVIQAYTEPAANYLHSQQVYTQG---------GTVTTIVTS---QPVQ-QEMIVPNNIIDLPPPSPPKPKTIILPPSWKVARDPEGRIYYYHIITRQTQWDPPSWDGTTEEASVEHEAEMDLGTPTYDENPSKFS--TKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKLGRISNTEDFKHLARKLTHGVMNKELKSCKNPEDLECNENVKHKTKEYIKKYMQKFGSVYRPKEDTELD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : :** : :: . *:**. * ::** : * :.::* **.*****************:: ***. ** **.. . **.:. ...: . * :.:: *:* : : * :.. . * .*.. . : *:.: .. **. ::: :..* ::***. .. :.: .* .: : .* ..: :* : : :: *. :.*****:: .*.* ** :. **: * :. : * *:* :*.******:*:* : .:. :.. : * *: *: :*.* **:. . ::: :** :**:*::*** .**:*:***::*:*** . . ******** **::*:**:*****:*** * **. **.*:*:*****:::::* .* :.: ** **. ::*.*:.* . *.: ** *: :...: ::. * .* **.** : .: : **: . : .**:.** *. . . *: *. * :: .: : : .. . .. *.: .* * * ::: ..: : :.::* : : *: :..:: . *. . *.* . .. .:*: .::.. :..::*.* *. :... :. * * : . * : . * :: :. * *:. .::: *. .. : . .** *.:::: . **: :.*: .* .*: . :*. . *. . . .. :: :* ::* ** : ..* :. * ::* :* . : .: .:.. :*. *: : . *:::* .*: : * *: : .. : . :: ** . * : . *** .. ::.*.. *...**:..*::***. :. :**:**********:.:* .. ... .:.* :*.. : *: .: : :: .:. : .. *:**: : . . . . . :.**: *****: : * :.: * . :.: . * .:**. :*. :: : .**** . * ::*.. : * .* ***.* *:*::*:*******.: * . .: * . .. : .. . :* : *****:*::: *:.. . :. : . *********. : * .: .:: ::: : *** ******:**:*:.:.* *: :::.: *. . : * :.:* ** *:: ** *** ********:*********************: ***:***:* :******************* ** ******** ***** ******.*********** .**************:************************:****** ****************************:****** *.:*:*********************:..*** :***.***:****** ::******* ::* ***** ******..:::*:**.*****:**:**:****:*****:. ***.**::********:*.**.:.: .* *** **:*:*. ***.********:** :****:*:: ::. :* ******.****:******* *.:* :** * ****: ::**********:***:**.:. : *: : *: :::* : ** * * *::*: : * * ::..* .:* :* ** *:. * **:* ...:: . ******************** :: ****:*::*******************.***.. .*.*:: : :.: :*.*::: *:: :. ::::**.* ** *..**** ::* ****: .:* ***:: *: *.************************** *: ..*.::.*.*.:. : * .******:*:****:************.::*:* **. . ** :. .:.. : . ... :.*:.*.:*:** :* . .* **..*.*:.* * . * * .:*:.* **:*:** ****. :*.*::******.* *:*.:.: *.**.**::*:*::*: :*::.**::* .:**:**:. *.:* **:*.**::*************:***.**.******:*****:**********:*:.. ::**:***************** * * .****************************************:***:.********************* *****************************:**:*******:", "identical_positions": 1029, "similar_positions": 725, "identity": "34.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2143", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI78-1", "uniprot_id": "ODO1_RAT", "id": "Q5XI78-1", "name": "2-oxoglutarate dehydrogenase complex component E1", "aln": "MFHLRTCAAKLRPLTASQTVKTFSQN----KPAAI-RTFQQIRCYSAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKSWDIFFRNT-NAGAPPGTAYQSPLSLSRSSLATMAHAQSLVEAQPNVDKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKLGFYGLHESDLDKVFHLPT---TTFIGGQEPALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDMSSANGVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAAD-EGSGDMKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGK-KVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRNTFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFTRSKDEKILHIKHWLDSPWPGFFT-LDGQPRSMTCPSTGLEEDILTHIGNVASSVP--VENFTIHGGLSRILKTRRELVTN-RTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFNNMAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPNLQEENFDISQLYDCNWIVVNCSTPGNFFHVLRRQILLPFRKPLIVFTPKSLLRHPEARTSFDEMLPGTHFQRVIP--EDGPAAQNPDKVKRLLFCTGKVYYDLTRERKARDMAEEVAITRIEQLSPFPFDLLLKEAQKYPN-AELAWCQEEHKNQGYYDYVKPRLRTTIDR-------------------------------------------------------------------------------------------------AKPVWYAGRDPAAAPATGNKKTHLTELQRFLDTAFDLDAFKKFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60597-1", "uniprot_id": "ODO1_MOUSE", "id": "Q60597-1", "name": "2-oxoglutarate dehydrogenase complex component E1", "aln": "MFHLRTCAAKLRPLTASQTVKTFSQN----KPAAI-RTFQQIRCYSAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKSWDIFFRNT-NAGAPPGTAYQSPLSLSRSSLATMAHAQSLVEAQPNVDKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKLGFYGLHESDLDKVFHLPT---TTFIGGQEPALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDMSSANGVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAAD-EGSGDMKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGK-KVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRNTFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFTRSKDEKILHIKHWLDSPWPGFFT-LDGQPRSMTCPSTGLEEDVLFHIGKVASSVP--VENFTIHGGLSRILKTRRELVTN-RTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFNNMAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLQEENFDINQLYDCNWIVVNCSTPGNFFHVLRRQILLPFRKPLIVFTPKSLLRHPEARTSFDEMLPGTHFQRVIP--ENGPAAQDPHKVKRLLFCTGKVYYDLTRERKARNMEEEVAITRIEQLSPFPFDLLLKEAQKYPN-AELAWCQEEHKNQGYYDYVKPRLRTTIDR-------------------------------------------------------------------------------------------------AKPVWYAGRDPAAAPATGNKKTHLTELQRFLDTAFDLDAFKKFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02218-1", "uniprot_id": "ODO1_HUMAN", "id": "Q02218-1", "name": "2-oxoglutarate dehydrogenase complex component E1", "aln": "MFHLRTCAAKLRPLTASQTVKTFSQN----RPAAA-RTFQQIRCYSAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKSWDIFFRNT-NAGAPPGTAYQSPLPLSRGSLAAVAHAQSLVEAQPNVDKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKLGFYGLDESDLDKVFHLPT---TTFIGGQESALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDKSSENGVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAAD-EGSGDVKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGK-KVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRSTFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFARSKDEKILHIKHWLDSPWPGFFT-LDGQPRSMSCPSTGLTEDILTHIGNVASSVP--VENFTIHGGLSRILKTRGEMVKN-RTVDWALAEYMAFGSLLKEGIHIRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLKEANFDINQLYDCNWVVVNCSTPGNFFHVLRRQILLPFRKPLIIFTPKSLLRHPEARSSFDEMLPGTHFQRVIP--EDGPAAQNPENVKRLLFCTGKVYYDLTRERKARDMVGQVAITRIEQLSPFPFDLLLKEVQKYPN-AELAWCQEEHKNQGYYDYVKPRLRTTISR-------------------------------------------------------------------------------------------------AKPVWYAGRDPAAAPATGNKKTHLTELQRLLDTAFDLDVFKNFS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8JI08-1", "uniprot_id": "B8JI08_DANRE", "id": "B8JI08-1", "name": "2-oxoglutarate dehydrogenase complex component E1", "aln": "MHRLRTCAARLRPITASQTAKNLSQQ----GPAATPRTFQPLRCFSSPVAAEPFLNGTSSNYVEEMYYAWLENPKSVHKSWDIFFRNA-NAGAPPGTAYQSPPPLG-VSLAGLAQAQSLVGAQPNVEKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGIMDADLDSCVPTDIITSSDKLGFYGLEESDLDKVFRLPT---TTFIGGDESALPLREIIRRLEMAYCQHIGVEFMFINDLDQCQWIRQKFERPGVMQFSLEEKRTLLARMVRSTRFEEFLQRKWSSEKRFGLEGCESLIPALKTIIDKSSENGVDTVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAAD-EGSGDVKYHLGMYHRRINRVTNRNITLSLVANPSHLEAVNPVVQGKTKAEQFYSGDTDGK-RVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVANNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAVMYVCNVAAEWRATFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIKKQKGVLQKYAEKLIAEGAVTRQEYEEEIAKYDKICEEAHSRSKDEKILHIKHWLDSPWPGFFT-LDGQPKSISCPSTGLPEEELAQIGQVASSVP--VEDFTIHGGLSRILKGRGDMIKN-RTVDWALGEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQNVDKRICIPMNHMSPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDFNPKITD-DFDVRQLYDCNWIVVNCSNPANYFHVIRRQILLPFRKPLIVFTPKSLLRHPEAKSNFDQMLPGTHFQRVIT--DDGPPAQNPSEVKRIVFCTGKIYYELTRERKARNMENSVAITRIEQLSPFPFDLVRAETEKFPN-ADLVWCQEEHKNQGYYDYVKPRMRTTINR-------------------------------------------------------------------------------------------------TKPVWYAGREPAAAPATGNKNTHLLELKRFLDTAFNLDAFKDHI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JNU6-1", "uniprot_id": "A8JNU6_DROME", "id": "A8JNU6-1", "name": "2-oxoglutarate dehydrogenase, mitochondrial", "aln": "MHRAHTAFSLALSPMAHKNFATWLLKSSSSQQMAKVTAAAAVRTYNS-AAAEPFANGSTASYVEEMYNAWLRDPTSVHTSWDAYFRSN-SYVSPP---NLAPVQANTLPLTAFNFGGAVAGAAPDS-KTIDDHLAVQAIIRSYQIRGHNIAHLDPLEINTPELPGNSSTKSIYAN-----FSFGEQDMDRQFKLPS---TTFIGGDEASLPLKEILNRLENVYCNKIGVEFMFINSLEQCNWIRKRFETPGVLNFSPEEKRLILARLTRATGFEAFLAKKYSSEKRFGLEGCEIMIPALKEIIDVSTELGVESVIMGMPHRGRLNTLANVCRKPLNQIFTQFAG-LEAAD-DGSGDVKYHLGTYIERLNRVTNKNIRLAVVANPSHLEAVDPVVQGKTRAEQFYRGDQEGK-KVMSILIHGDAAFCGQGVVYETMHLSDLPDYTTHGTIHVVANNQIGFTTDPRFSRSSPYCTDVARVVNAPIFHVNADDPEAVMHVCKVAAEWRATFHKDCVIDLVGYRRNGHNEIDEPMFTQPLMYQKIRKHKNCLDLYADKLIAEGTVTAEEVKSVAAKYENICEEAFALAKTETHVKYKDWLDSPWSGFFE-GKD---PLKVAPTGVKEETLIHIGNRFSSPPPNAAEFVIHKGLLRVLAARKAMVDE-KVADWALGEAMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHHQLVDKATYNSLQHMYPDQAPYSVSNSSLSEYAVLGFEHGYSMTNPNALVLWEAQFGDFSNTAQSIIDQFISSGQSKWVRQSGLVMLLPHGMEGMGPEHSSCRVERFLQMSSDDPDYFPPESD-EFGVRQLHDINWIVANCSTPANYYHILRRQIALPFRKPLILCTPKSLLRHPEAKSPFSEMSEGSEFQRIIP--DNGPAGQNPSNVKKVVFCSGRVYYDLTKTRREKQLEGEIAIVRVEQISPFPFDLVKEQANLYKN-AELVWAQEEHKNQGSWTYVQPRFLTALNHSRDVSQSDEQSSSTNTTTTTDHTNHESDTDSDSKSKPWLSRMFAAPNSSTGGDPKDPAQTLGGDFNAAKHFDLKNVRHDFNRPAGIAAAPGARIAKTGRKISYVGRACGASTATGSKAQHIRELNALLNDAIST-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20967-1", "uniprot_id": "ODO1_YEAST", "id": "P20967-1", "name": "2-oxoglutarate dehydrogenase, mitochondrial", "aln": "--MLRFVSSQTCRYSSRGLLKTSLLK--------NASTVKIVGRGLATTGTDNFLSTSNATYIDEMYQAWQKDPSSVHVSWDAYFKNMSNPKIPATKAFQAPPSISNFPQGTEAAPLG-TAMTGSVDENVSIHLKVQLLCRAYQVRGHLKAHIDPLGIS----FGSNKNNPVPPELTLDYYGFSKHDLDKEINLGPGILPRFARDGKSKMSLKEIVDHLEKLYCSSYGVQYTHIPSKQKCDWLRERIEIPEPYQYTVDQKRQILDRLTWATSFESFLSTKFPNDKRFGLEGLESVVPGIKTLVDRSVELGVEDIVLGMAHRGRLNVLSNVVRKPNESIFSEFKGSSARDDIEGSGDVKYHLGMNYQRP-TTSGKYVNLSLVANPSHLESQDPVVLGRTRALLHAKNDLKEKTKALGVLLHGDAAFAGQGVVYETMGFLTLPEYSTGGTIHVITNNQIGFTTDPRFARSTPYPSDLAKAIDAPIFHVNANDVEAVTFIFNLAAEWRHKFHTDAIIDVVGWRKHGHNETDQPSFTQPLMYKKIAKQKSVIDVYTEKLISEGTFSKKDIDEHKKWVWNLFEDAFEKAKD-YVPSQREWLTAAWEGFKSPKELATEILPHEPTNVPESTLKELGKVLSSWP---EGFEVHKNLKRILKNRGKSIETGEGIDWATGEALAFGTLVLDGQNVRVSGEDVERGTFSQRHAVLHDQ-QSEAIYTPLSTLNNEKADFTIANSSLSEYGVMGFEYGYSLTSPDYLVMWEAQFGDFANTAQVIIDQFIAGGEQKWKQRSGLVLSLPHGYDGQGPEHSSGRLERFLQLANEDPRYFPSEEK---LQRQHQDCNFQVVYPTTPANLFHILRRQQHRQFRKPLALFFSKQLLRHPLARSSLSEFTEGG-FQWIIEDIEHGKSIGTKEETKRLVLLSGQVYTALHK-RRESLGDKTTAFLKIEQLHPFPFAQLRDSLNSYPNLEEIVWCQEEPLNMGSWAYTEPRLHTTLKET--------------------------------------------------------------------------------------------DKYKDFKVRYCGRNPSGAVAAGSKSLHLAEEDAFLKDVFQQS------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . : : : : ..:: * . :.:.*::*** ** .:*.*** *** :*:. . *. :* . . . . . : :. ** ** : *:**:*** *::*** * . . : . :.: : *:*: :.* . . * . :. :.*:**: :** **. **:: .* . ::*:*:*:::* * ::: ::** :* *:. :* ** ** *:..:******* * ::*.:* ::* * **: :::**.******.*:** ** :.** :* . * :****:***** .* .:.: : *::********: :*** *:*:* . .* . * :.:.:*:******.***:****: : **.*:* **:**:.***********::**:** :*:*:.::*******::* *** .: ::***** .**.* ::*:* :*::**** *:* *******::* *:* :: *:: *:::*... : .. :: *:*. :* :.** :.* ** . : .*.: *. * .:*: ** * * :* .* *:* * : . *** .* :***:*: :* ::*:**:********:** ***.* .: .:. : ::* :::.*******.*:*** *::::.*: **:******** * ** ******. *: ** ::.*:*: **** :* ****** * *****:..:** * . * * *: *. :.*.* :*::*** ***** : .*.***** *:: :.:: * ** :* :.* . :.*:::: :*::* * : *: *: ::**: **** : . : : * ::.*.*** * * : *.:**: *::.. : * ** ..: *:*.* *: * . :*. .:. ", "identical_positions": 363, "similar_positions": 310, "identity": "31.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2144", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17988-1", "uniprot_id": "ST1A1_RAT", "id": "P17988-1", "name": "Sulfotransferase 1A1", "aln": "---------MEFSRPP-----------LVHVKGIPLIKYFAETIGPLQNFTAWPDDLLISTYPKSGTTWMSEILDMIYQ-GGKLEKCGRAPIYARVPFLEFKCPGVP-SGLETLE--------ETPAPRLLKTHLPLSLLPQSLLDQKVKVIYIARNAKDVVVSYYNFYNMAKLHPDPGTWDSFLENFMDGEVSYGSWYQHVKEWWELRHTHP-VLYLFYEDIKENPKREIKKILEFLGRS--LPEETVDSIVHHTSFKKMKENCMTNYTTIPTEIMDHNVSPFMRKGTTGDWKNTFTVAQNERFDAHYAKTMTDCDFKFRCEL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0DMM9-1", "uniprot_id": "ST1A3_HUMAN", "id": "P0DMM9-1", "name": "Sulfotransferase 1A3", "aln": "-----MELIQDTSRPP-----------LEYVKGVPLIKYFAEALGPLQSFQARPDDLLINTYPKSGTTWVSQILDMIYQ-GGDLEKCNRAPIYVRVPFLEVNDPGEP-SGLETLK--------DTPPPRLIKSHLPLALLPQTLLDQKVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWDSFLEKFMAGEVSYGSWYQHVQEWWELSRTHP-VLYLFYEDMKENPKREIQKILEFVGRS--LPEETMDFMVQHTSFKEMKKNPMTNYTTVPQELMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52847-1", "uniprot_id": "ST1B1_RAT", "id": "P52847-1", "name": "Sulfotransferase 1B1", "aln": "-----MGTAEDVFRKD-----------LKIIHGYPMVYAFALGWEKIEEFQSRPCDIVIPTYPKSGTTWLSEIVDMVLN-DGNVEKCKRDVITSKVPMLEQNVPGARRSGVELLK--------KTPSPRIIKTHLPIDLLPKSFWDNKCKMIYLARNGKDVAVSYYHFDLMNNIQPLPGTWEEYLEKFLAGNVAYGSWFDHVKSWWEKREGHP-ILFLYYEDLKKNPKKEIKKIANFLDKT--LDEHTLERIVHHTSFEVMKDNPLVNYTHLPTEIMDHSKSPFMRKGVVGDWKNYFTMTQSEKFDAIYKKKLSGTTLEFCTDIQSA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QWG7-1", "uniprot_id": "ST1B1_MOUSE", "id": "Q9QWG7-1", "name": "Sulfotransferase 1B1", "aln": "-----MSASEDVWRKD-----------LKMIHGYPMIYAFALNWERIEEFQSTPGDIVITTYPKSGTTWLSEIVDMVLN-DGNVEKCKRDVITSKVPMLELSVPGIRISGVELLK--------KTPSPRIIKTHLPIDLLPKSFWENKCKMIYLARNGKDVAVSYYHFDLMNSINPLPGTWEEYLEKFLAGNVAYGSWFDHVKSWWEKREEHP-LLYLYYEELKQNPKKEIKKIASFLDKT--LDEEALDRIVHHTSFEMMKENPLVNYTHLPTAMMDHSKSPFMRKGIVGDWKNYFTMTQTEQFDAVYKKKMSGTTLEFCTDIQSA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52844-1", "uniprot_id": "ST1E1_RAT", "id": "P52844-1", "name": "Sulfotransferase 1E1", "aln": "-----METSMPEYYEV-----------FGDFHGVLMDKLFTKYWEDVETFSARPDDLLVVTYPKSGSTWIGEIVDMIYK-EGDVEKCKEDAIFNRIPYLECR-NEDLINGIKQLK--------EKESPRIVKTHLPAKLLPASFWEKNCKIIYLCRNAKDVVVSYYYFFLIIKSYPNPKSFSEFVEKFMEGQVPYGSWYDHVKSWWEKSKNSR-VLFMFYEDMKEDIRREVVKLIEFLERD--PLAELVDKIIQHTSFQEMKNNPCTNYSMLPETMIDLKVSPFMRKGIVGDWRNHFPEALRERFEEHYQRHMKDCPVKFRAEL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49891-1", "uniprot_id": "ST1E1_MOUSE", "id": "P49891-1", "name": "Sulfotransferase 1E1", "aln": "-----METSMPEYYEV-----------FGEFRGVLMDKRFTKYWEDVEMFLARPDDLVIATYPKSGTTWISEVVYMIYK-EGDVEKCKEDAIFNRIPYLECR-NEDLINGIKQLK--------EKESPRIVKTHLPPKLLPASFWEKNCKMIYLCRNAKDVAVSYYYFLLMITSYPNPKSFSEFVEKFMQGQVPYGSWYDHVKAWWEKSKNSR-VLFMFYEDMKEDIRREVVKLIEFLERK--PSAELVDRIIQHTSFQEMKNNPSTNYTMMPEEMMNQKVSPFMRKGIIGDWKNHFPEALRERFDEHYKQQMKDCTVKFRMEL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49888-1", "uniprot_id": "ST1E1_HUMAN", "id": "P49888-1", "name": "Sulfotransferase 1E1", "aln": "------MNSELDYYEK-----------FEEVHGILMYKDFVKYWDNVEAFQARPDDLVIATYPKSGTTWVSEIVYMIYK-EGDVEKCKEDVIFNRIPFLECR-KENLMNGVKQLD--------EMNSPRIVKTHLPPELLPASFWEKDCKIIYLCRNAKDVAVSFYYFFLMVAGHPNPGSFPEFVEKFMQGQVPYGSWYKHVKSWWEKGKSPR-VLFLFYEDLKEDIRKEVIKLIHFLERK--PSEELVDRIIHHTSFQEMKNNPSTNYTTLPDEIMNQKLSPFMRKGITGDWKNHFTVALNEKFDKHYEQQMKESTLKFRTEI---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PH37-1", "uniprot_id": "ST1S1_DANRE", "id": "Q6PH37-1", "name": "Cytosolic sulfotransferase 1", "aln": "--MDIPDFSSISSRPT-----------IFEFEGISMINHFTENWEKVKNFQARPDDILIATYPKAGTTWVSYILDLLYFGENAPEEHTSQPIYMRVPFLESC-FKVIASGTELADN-------MTTSPRLIKTHLPVQLIPKSFWEQNSRVVYVARNAKDNVVSYFHFDRMNIVEPDPGDWNTFLHRFMDGKSVFGPWYDHVNGYWEKKQTYSNLLYLFYEDLVEDTGREVDRLCSFLGLS--TSVSDREKITKDVQFDAMKQNKMTNYSTLP--VMDFKISPFMRKGKVGDWKNHFTVAQNEQFDEVYKEKMKNATVKFRTEI---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHH0-1", "uniprot_id": "Q9VHH0_DROME", "id": "Q9VHH0-1", "name": "", "aln": "MQLIYRELEEDILRRTNAVFPVQNCFVEVLPDQFIIPRKYVELGESIRSLPVYQDDVWMVSYPRTGSTWAQEMVWLLGHQLDYVAAEQDLRLRSPLIELSALFSIDHHETVAQKFGNTVDLVRNLPRPRFARSHLPWPLLPEQFETVKPRIVYTARNPKDLCVSYYHYFKLLHG--MNGDFEQFVDLFLEGHTPMGSYWRHVLPFWKRSQDDN-VLFIKYEDMVKDLPSVVRRCARFLGVQSLLDVSTLQKLCDHLTFDKMRANKAVN----LEKLLPESSSKFIRNGKIGDWRNHMGNEMSERFDEWTERHMRGSGLNFDYV----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. :. : *: : :**::*:** :: :: . : : *. . **: ::*** *:* : . :::* .** ** **:: : : : ::. *: *. *.:: ** :*: . :*:: **:: :: : : *: : : .. *. *: * .* :: . * *:*:* ***:. : *:*: . : ..* ", "identical_positions": 45, "similar_positions": 78, "identity": "13.76%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2145", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZV49-1", "uniprot_id": "A0A8I5ZV49_RAT", "id": "A0A8I5ZV49-1", "name": "", "aln": "MSSSHSRSGQSAAGASPAGGIDT--RDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEED--EEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGIGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPTACRAVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKG-EERVKQKDLGDGVYGFEYYPTIPGTYTVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGIVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAP-QDFHPDRVKARGPGLEKTGVAINKPAEFTVDAKHAGKAPLRVQVQDNEGHSVETTVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCTEAGQGDVSIGIKCAPGVVGPTEADIDFDIIRNDNDTFTVKYTPCGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLNRTGVELGKPTHFTVNAKTAGKGKLDVQFSGLAKGDAVRDVDIIDHHDNTYTVKYTPVQQGPVGVSVTYGGDHIPKSPFSVGVSPSLDLSKIKVSGLVDKVDVGKDQEFTVKSKGAGG---QGKVASKIVSPSGAAVPCKVEPGLGADNSVVRFVPREEGPYEVEVTYDGVPVPGSPFPVEAVAPTKPSKVKAFGPGLQGGNAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQDCGDGTYKVEYTPYEEGVHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGL-VEPVDVVDNADGTQTVNYVPSREG-SYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTVSIGGHGLGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSE-VDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPTVQTPLRPQQLPSQYTYPQGSQQTWIPERPMVGVNGLDVTSLRPFDLVIPFTIKKGEITGEVRMPSGKVAQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGDDSMRMSHLKVGSAADIPIN--ISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEG--RVKESITRRRRAPSVANVGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFGIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGPG--PADVSKVVAKGLGLSKAYVGQKSNFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMVP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BTM8-1", "uniprot_id": "FLNA_MOUSE", "id": "Q8BTM8-1", "name": "Filamin-A", "aln": "MSSSHSRCGQSAAVASPGGSIDS--RDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEED--EEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPAACRAIGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKG-EERVKQKDLGDGVYGFEYYPTIPGTYTVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGIVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAP-QDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHAGKAPLRVQVQDNEGCSVEATVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCTEAGQGDVSIGIKCAPGVVGPTEADIDFDIIRNDNDTFTVKYTPCGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLNRTGVELGKPTHFTVNAKTAGKGKLDVQFSGLAKGDAVRDVDIIDHHDNTYTVKYIPVQQGPVGVNVTYGGDHIPKSPFSVGVSPSLDLSKIKVSGLGDKVDVGKDQEFTVKSKGAGG---QGKVASKIVSPSGAAVPCKVEPGLGADNSVVRFVPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGNAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVAPCFDASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQDCGDGTYKVEYTPYEEGVHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGL-VEPVDVVDNADGTQTVNYVPSREG-SYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTVSIGGHGLGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSE-VDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPTVQTPLRSQQLAPQYNYPQGSQQTWIPERPMVGVNGLDVTSLRPFDLVIPFTIKKGEITGEVRMPSGKVAQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGDDSMRMSHLKVGSAADIPIN--ISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEG--RVKESITRRRRAPSVANIGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEVGVPAEFGIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGPG--PADVSKVVAKGLGLSKAYVGQKSNFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMVP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21333-1", "uniprot_id": "FLNA_HUMAN", "id": "P21333-1", "name": "Filamin-A", "aln": "MSSSHSRAGQSAAGAAPGGGVDT--RDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEED--EEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGTGEVEVVIQDPMGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKG-EERVKQKDLGDGVYGFEYYPMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIRDAP-QDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVEALVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCAEAGQGDVSIGIKCAPGVVGPAEADIDFDIIRNDNDTFTVKYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAGKGKLDVQFSGLTKGDAVRDVDIIDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGG---QGKVASKIVGPSGAAVPCKVEPGLGADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGL-VEPVDVVDNADGTQTVNYVPSREG-PYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTVSIGGHGLGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSE-VDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIKKGEITGEVRMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGSAADIPIN--ISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEG--RVKESITRRRRAPSVANVGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAGALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPG--PADASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRVVVP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AYA1-1", "uniprot_id": "A0A8M3AYA1_DANRE", "id": "A0A8M3AYA1-1", "name": "", "aln": "-MSQHTRPHQSSAAAPLSNASLSPDKDADMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIANLQTDLSDGLRLIALLEVLSQKKMFRKYNQRPTFRQMQLENVSVALEFLDIENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEES-EESKQKTPKQRLLGWIQNKLPELPITNFSRDWQSGKALGALVDSCAPGLCPDWDSWDQTKPVDNAREAMQQADDWLGVPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNVVMKKAVFTVETISAGQGEVLVYVEDPAGHREEAKVTANNDKNRTYSVFYVPKVTGQHKVTVLFAGQHISKSPFEVDVGMAQGDSSKVTAQGPGLEPAGNIANKTTYFDVYTAGAGVGEVEVVIMDPSGKKDTVECSVEDKGNSSYRCTYKPTQEGQHIIYITFAGGQISKSPYTVNVGEACNPSLCTAKGRGLQPKGLRVKETAEFKVYTKGAGTGDLKVTIKGPKGLEEPCKKKDLGDGVYSFDYYPSTPGNYIITITWGGQHIPRSPFEVKIGSEAGPQQVRAWGPGLESGVVGKSADFVVEAVGDDVGTLGFSVEGPSPAKIECDDKGDGSCDVRYWPTEPGEYAVHVLCKNEDIQLSPFMAEIMPAPGKDFYPDKVKAYGPGLQSSGLSVGKPAEFTVDAKLGGKAPLKIQAQDRDGNPVDVQVKDNGNGTYSCSYTPRKPVKHTVMVSWGGVNIPESPFRMNIGAGCHPNKVKVSGPGVAKTGLKAYDPTYFTVDCAEAGQGDISIGIKCAAGVVGPAEADIDFDIIRNDNDTFTVKYTPPGAGSYTIMVLFADQTIPMTPIRIKVDPSHDASKVKAEGPGLSRSGVELNKPTHFTVNTKAAGKAKLDAQFTGPNKGDAVRDFDIIDNHDGTHTVKYTPVQQGNMGLNVTYGGDPIPKSPFAVAIAPSLDLSKVKVAGLGSKMTVGKDQEITVKSKGAGG---QGKVGAKVTGPSAKSVPCKVEPGLSPETSQVRFIPRDKGPYEVELTYDGAPIPGSPFPIEAIAPTDPS---------------------------------------------------------------------------------------------KVRCSGPGLERAKVGEPGQFVVDCTNAGPAELTIEIISDNGTEAEVHIQDNGDGTYTITYVPLYPGAYTLTIRYGDQDVPNFPARLHVEPAVETSGVKVFGPGVEGKGVFREATTDFTVDARALTKTGGNHIKTCINNPSGNRTEALIRDLGDGTYQVEYTPYEEGTHSVEVAYDSSPVPKSPFRVPVTEGCDPARVRVHGPGLQSGITNKPNKFTVETRGAGTGGLGLAMEGPSEAKMSCTDNKDGSCCVEYIPYEPGTYNLNVTYGGQPITGSPFSVPVHDTVDPTKVKCQGQGLG-NNVRANIPQVFSVDASKAGMAPLQVRVQGPKGV-VEPAEVVDNGDQTHTVSYVPTREG-PYSINVLYADEEIPQSPYKVKVLPTHDASKVRCSGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPDGKPKKANIRDNQDGTYLVSYVPDMTGRYTILIKYGGDEIPYSPYRIRALPTGDASKCTVTVSIGGHGLGAGVGPTIQIGEQTVITVDAKAAGKGKVTCTVCTPDGGE-VDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHIPNSPFQVTALEGDSP---DQLMQQSQNLQYAYAPNMGQTWATDG-QLGMNGLDVAGLRPFDLVIPFTIQKGEITGDVRMPSGKVAKPDITDNKDGTVTVKYAPTEAGLHEMDIKYDGIHIPGSPLQFYVDYVNSGHVTAYGPGLIHGMVNKPAVFTVNTKDAGEGGLSLAIEGPSKADISCTDNQDGTCTVSYLPVLPGDYNIIVKYNDKNIPGSPFMSKITGDDSMRMSHLKVGSAADIPLD--IGELDLSQLTATLTTPSGREEPCLLKMLRNGHVGISFVPKEIGEHLVNIKKNGRHIPSSPISVMINQSEIGDASRVRVTGQGLSEARTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDQEDGTCKVTYCPTEPGNYIINIKFADQHVPGSAFTVKVTGEG--RMKESITRKRRAASVANVGSQCDLSLKIPEISIADMTAQVTSPSGKVHKAEIMEGENNTYCIRFVPTEMGVHTVSVKYQGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDEHIPDSPFVVPVASPSDDARRLTVASLQESGLKVNQPASFAVSLNGAKGVIDAKVHSPSGALEECCVTEIDEDKYAVRFIPRENGLYLIDVKFNGSHIPGSPFKIRVGETGQAGDPGMVSAYGAGLEGGTTGSPCEFIVNTSSAGPGALAVTIDGPSKVKMDCQECPEGYKVTYTPMAPGNYLISIKYGGPYHIVGSPFKAKITGSRLVNSHSMHETSSVLVDPVTRSMTTSQQAAPGWA--SSDASRVVAKGLGLNKGFIGQKNTFSVDCSKAGRNMLLVGVDGPKVPCEEILVKHLGNRLYNVSYQLKEKGEYILVVKWGDEHIPGSPYHITV-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEN1-1", "uniprot_id": "FLNA_DROME", "id": "Q9VEN1-1", "name": "Filamin-A", "aln": "------------------------------MEAERDLAEDAQWKKIQQNTFTRWANEHLKTIDRSINNLETDLSDGLRLIALIEVLSQKRMP-KYNKRPTFRSQKLENVSVALKFLQDEGIKIVNIDSSDIVDCKLKLILGLIWTLILHYSISMPMWDGEDDKQLNGSGHTPKQRLLNWIHAKIPDLPINNFTNDWTTGKAVGALVDACAPGLCPDWELWDPKDAVQNASEAMGLADDWLNVRQLIKPEELVNPNVDEQSMMTYLSQYPNSKLKTGAPLRPKTNPNRVRAYGPGIEPIGPVVGAPANFTVETFSAGKGSVDVDIQGPNGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFSGRDIPKSPFPVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPANHKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFPVKVAPLSDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGMNQNVMQSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEVKVGPKK-ESSIVAYGPGLSSGVIGYPAAFVVETNG-ETGALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPFIAQILPRT--DFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAGNAPLDVVVQDVFGTKLPVELKNNPDGTKKVTYTPTSGVPHTVEVNYGGVSTPNSPHRVYVGVPVDAAKVQAFGP-WLQPGVRPNAATHFNVDAREAG------------------------------------------------------------DAELKVKIIHEETKIEVP--------------------------------------------CRIIDNEDNTYSVEVIPPSKGAYTTTMTYGGQRVPLG-EKVVVEQTVDVSKIKVDGLEPSVIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKIVQGP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNVKSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVDPSKVKVYGPGIEHGQVRESVPTFFNVDVGEAGPGRIAVKLTNSEGIPVDNLRVEDKGNCIYAVHYVPPKAGSVLTCQVKFSEVEVPCSPFVMTVFPKSEPTKVKVKGVNEKKK-TPASLPAEFEIDTKQAGQADINVAIKNPKGKAMQPRLEEVSTGTYVVSFVPDECGTYQCSIKYGDKEIEGSPFKLEAFPTGEAKKCKLVEQAP---------KIQTSGSQSHLKVDAREAGDGAVTCKITNKAGSEIVDIDVIE-KDGFFDILYALNDPGDYDINVKFGGKDIPNGSFSIKAVES---------IEQYSHSEYIEEHTTKVVQQTTQSELVNGKSEITYRSVAFEKLPLPTTGGNVTAEVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHVDSITSGYVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKRN-QISVGSCSEVTMPGDITDDDLRALNASIQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCEREVGDAKKVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREKIQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEVEDGLYAVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVKAGGSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDAGDAHKLEVQQFPQGNIQADAPYQFMVRKNGAKGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVHIPDSPFRIKVG--KDVADPAAVHASGNGLDEVKTGHKADFIINTCNAGVGTLAVSIDGPSKVAMDCTEVEEGYKVRYTPLLPGEHYITVKYNN-MHIVGSPFKVNATGDKLADEG-AQETSTVIVETVQKVAKGGKNTGVHLPTFKSDASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILYVGMYGPKGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKWGEEHIPGSPFQIDV-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:****** ************.***** :.: * **:************:******:* *:*:*****. :********:**: *.**:*.***. *** :*********************** *:: :.. :*******.**: *:*:***.**:.** :*:*:*****:*********: ** ...* ** *** *****.: *:*.***:*:*****:*:******:*::***.******* **::.********* * :* * ***** ***:*.* * ::.* *. *:*.* ***** *::* *:*: * ***:* *:*:.*.**** * * **:***.. ***::* * :*.*:*:: : .** * **:* ** .:* :* .:. :.::** * .: :* * : : :** *..**:.*.*. .:. * *****..*:** : *:**:**:*** *: :* : ** * :: :..:....* .*** * * : :*:.**.: :******:*.: ..: *:****..*::* .* ****: * :.*:***:* *** *:***.*:****. *:* * ******:**..*** ***:*:* . **:*: *** ****:..*:::.:*:.****.. .*:*** : .** * : . :*:* :** . :*.* . * **. *.:***. *:**.*: :*. .. **:. ** :.*::. .*:*.**. *** .:**. *: :*::. ***:.*.*::*: * .:* .:****: :* . * : ::*:**:** ** .: :. :: *. . .*. .**:.. : .* . :*.*: * *. ::: ***:* * *:::: **. *** *** * *..****:* :.:***::.* **: *******:***.***.**:********:* **:**** *:*:. :.* *.:.: :..: :.**** * *.:..*.:*** * *: . ** .:* *.**..:** . : *:: ..:*: *: * *:.: :* ***.: * : .* :.: *:* **: :.*:*. :.:**: .* . :.. .*****.** **:*:**:. : * *.:*.**. :..:.: *** *::*** * * ****..** **:::.*.***:*.**.:. . *.:: :.**:: **.* ***.: . *.* **:**:* :** ***:*: :**.* * *:***:.:**..*.:.*: . * :* . . : . ::: :*:. *::*.:******** :* * **:****:*:* * * * **: ::*:. : ***::*:** :..*::******* **:..:** **:.**.*. ***::*:******:*. **:*** :*.***. **:*.: *::.:::: ***: :::**:. * ::.***.:::.: * : ** *.*:: .*** ****:** : .*::****.*:* ***** :*: *:*: .**: * : : *:***.:*:*:* ** *.:*. * :***:**:****:*******.:*: * :*** .::* ***** **:*:****:** **.*:***:*** * :*.* *.* * .::::**:*.*::*:* *: *::* *****. ...*** * *: *.::*** *:* *****:*. *:************ :.*:* *:***.****. .* .***.:******.*.*:*:*******:* *:******..*:* * ***:*.*.:***:.******* * *:. :.**::* * .: :..::.: * .* * ***** :***: :***: ::* : ** : *:*** *****:: *.***** ***.***:*:** . .**. * * * **: ** .:*::**..** *:*:*:******* *** * ***:* ***: **.: *::**.. ** *****.: ** :*... :***:*:*:.: : :: :*.*:**:**:**.*.::*::. *::..:.**.*:* **: **: ****: *** * . *.*.* ::::*:* *::***:*******::: * ", "identical_positions": 1037, "similar_positions": 692, "identity": "38.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2146", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O00566-1", "uniprot_id": "MPP10_HUMAN", "id": "O00566-1", "name": "U3 small nucleolar ribonucleoprotein protein MPP10", "aln": "MAPQVWRRRTLERCLTEVGKATGRPECFLTIQEGLASKFTSLTKVLYDFNKILENGRIHGSPLQKLVIENFDDEQIWQQLELQNEPILQYFQNAVSETINDEDISLLPESEEQEREEDGSEIEADDKEDLE-DLEEEEVSDMGNDDPEMGERAENSSKSDLRKSPVFSDEDSDLDFDISKLEQQSKVQNKGQGKPRE------KSIVDDKFFKLSEMEAYLENIEKEEERKDDNDEE-EEDIDFFEDIDSDEDEGGLFGS---KKLKSGKSSRNLKYKDFFDPVESDED-ITNVHDDELDSN----KEDDEIAEEEAEELSISETD-----EDDDLQENEDNKQHKESLKRVTFALPDDAETEDTGVLNVKKNSD----EVKSSFEKRQEKMNEKIASLEKELLEKKPWQLQGEVTAQKRPENSLLEETLHFDHAVRMAPVITEETTLQLEDIIKQRIRDQAWDDVVRKEKPKEDAYEYKKRLTLDHEKSKLSLAEIYEQEYIKLNQQKTAEEENPEHVEIQKMMDSLFLKLDALSNFHFIPKPPVPEIKVVSNLPAITMEEVAPVSVSDAALLAPEEIKEKNKAGDIKTAAEKTATDKKRERRKKKYQKRMKIKEKEKRRKLLEKSS---VDQAGKYSKTVASEKLKQLTKTGKASFIKDEGKDKALKSSQAFFSKLQDQVKMQINDAK-KTEKKKKKRQDISVHKLKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q810V0-1", "uniprot_id": "MPP10_MOUSE", "id": "Q810V0-1", "name": "U3 small nucleolar ribonucleoprotein protein MPP10", "aln": "MAPRVFRRQTLERCLREIRKATNRPECFLTIQNGLASNFTSLTKVLYDFNKVLENGRISGSPLQKLEINSFDDEQIWQQLELQNEPVLQYFQNAVSETVEDEDISLLPECEDEECEEDASEVEADNQENLETDLDEEQLSDEGGDVPKGRDRAKSSRKSDPRKSPVFSDEDSDLDFDIGKLEQQTKMQIKPPGKPRE------KSVVDDKFFKLSEMESFLEKVEKEEEKRPDGEEEDEEDIDLFEDIDSDESEGGLFGR---QKIKSNKSSRNLKYKDFFDPVESDED-ITGVDEELGPDE----EKEEEEGFAEEADESISDTD-----EDNDLEEDENSDQHKGSLKRVTFALPDD-EAEDTSPLAVKQESD----EVKSSFEKRQEKMNEKIASLEKELLDKKPWQLQGEVTAQKRPENSLLEETLHFDHAVRMAPVITEETTLHLEDIIKQRIRDQAWDDVERKEKPKEDAYEYKKRLTLDHEKSKLSLAEIYEQEYLKLNQQKTEEEDNPEHVEIQKMMDSLFLKLDALSNFHFIPKPPVPEIKVVSNLPAITMEEVAPVSVSDAALLAPEEIKEKNKAGDLKTAAEKTATDKKRERRKKKYQKRLKIKEKEKRKKLLEKNN---PDQS-KSSRAAASEKLKQLTKTGKVSLLKDERKDKPLKSSQAFFSKLQDQVKMQINDAK-QPEKIKKKKQDISVHKLKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58FXL5-1", "uniprot_id": "A0AC58FXL5_DANRE", "id": "A0AC58FXL5-1", "name": "U3 small nucleolar ribonucleoprotein protein MPP10", "aln": "MATR--DGGTLESCLQLLNSNTSHPELFLSVQDVLATDFRSLTKTLYDLQKAHEPADCKGSPLEQLVVENFDEEQIWQELELQNSALLTHFEQAVEQAVTDDAITFLND-EGDDVEEDEEELEDVDDEEIADNLEQGSAEEE--DDEDAEEETTQRLKPTSNGEDDFSGEDSDLDFDVDKFEKQTKQRQSAAGKLTKSKPNWTQSEVDDKFFKLSEMEAFLDDMDKREGKGNE-----GEEIDYFQDLPSDEDDELSFDKPVVKKKLKNKSSRNMKYKDFFAPVDGEPDPIPDEEKELESNDDYEGEEQDDDELEEEDEEDMNEEDFDMERDDDDDDDDDIGDKVRDGSRRVTFDLPDDSEGEDVEDILGGKAKDVPKPESKSSFEKRQEKMVKQIEELENAALSEKPWQLSGEVTAQTRPENSMLEEDIAFDQASRMAPAITEETTLQLEDIIKQRIKDQVWDDVVRKEKPKEEVFEYKKRLTLDHEKSKLSLAEVYEQEYIKQTQEKKEEEENPAHVEIQKLMDSLFLKLDALSNFHFTPKPHVPEVKVVSNLPTITMEEVAPVNVSDATLLAPEEIKEKNKAGDILGDTEKTTTDKKRERRKKKKLKRLKIHEREKRQKLKEAARGGADDGKKKKSKAEVEQTIKKLTKGGKAKVLTNDGMDKALRSSQAFFSQLQDQVRSQVKGSKDQTGKKKKKQKEISVNKLKL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.: *** ** : . *.:** **::*: **:.* ****.***::* * . ****::* ::.**:*****:*****..:* :*::**.::: *: *::* : * :: *** .*:* :.*:: :*:: . .: * . :.: . *. . . **.********:.*:*:*:* : . ** : :* ************::*:.::*.* : : *:** *:*: ***.: *. :* ..*****:****** **:.: * *.. ..: .: ::::: * : .:.: * :*:* :::: ..: : . :**** **** * **. : : .* * *********** ::* .**: *.:*****.******.*****:*** : **:* ****.*******:*********:**.**** *******:.:*******************:*****:* .*:*. **:** ******:**************** *** ***:*******:*********.****:***************: :***:*********** **:**:*:***:** * * * *:: ..:.:*:*** **...:.:: **.*:*******:*****: *::.:* :. * ***:::***:****", "identical_positions": 359, "similar_positions": 188, "identity": "50.56%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2152", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96MT3-1", "uniprot_id": "PRIC1_HUMAN", "id": "Q96MT3-1", "name": "Prickle-like protein 1", "aln": "------------------MPLEMEPKMS---KLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRAVMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKFPGLSGNADDTLSRKLDDLSLS-RQGTSFASEEFWKGRVEQETPED-PEEWADHEDYMTQLLLKFGDKSLFQPQPNEMDIRASEHWISDNMVKS--KTELKQNNQSLASKKYQSDMYWAQSQDGLGDSAYGSHPGPASSRRLQELELDHG-ASGYNHDETQWYEDSLECLS--DLKPEQSVRDSMDSLALSNITGASVDGENKPRPSLYSLQNF--EEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSSELCPEKILPE-------------------EKPVHLPVLRRSKSQSRPQ----QVKFSDDVIDNGNY-DIEIRQPPMSERTRRRVYNFEE--------RGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSAREIQAYIQNADLYGQYAHATSDYGLQNPGMN---RFLGLYGEDD-DSWCS-SSSSSSDSEEEGYFLGQPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3U5C7-1", "uniprot_id": "PRIC1_MOUSE", "id": "Q3U5C7-1", "name": "Prickle-like protein 1", "aln": "------------------MPLEMEPKMS---KLVFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRAVMHAVCEQCGLQMNGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSKTCSLGEDIHASDSSDSAFQSARSRDSRRSVRMGRSSRSADQCRQSLLLSPALNYKFPGLSGNADDTLSRKLDDVSLASRQGAGFANEEFWKARVEQEASED-PEEWAEHEDYMTQLLLKFGDKNLFQQQSSEVDPRASEHWIPDNMVTN--KPEVKPNHQGLASKKYQSDMYWAQSQDGLGDSAYGSHPGPASSRRLQELDLDHG-AAGYTHDQSQWYEDSLECLS--DLKPEQSIRDSMDSLALSNITGASVDGESKPRPSLYSLQNF--EEIEAEDCEKMSNMGTLNSSMLHRSAESLQSLNSGLCPEKILPE-------------------EKPAHLPVLRRSKSQSRPQ----QVKFSDDVIDNGSY-DIEIRQPPMSERTRRRAYHFEE--------RGSRPHHHRHRRSRKSRSDNALNLVTERKYSAKDRLRLYTPDNYEKFIQNKSARELQAYMQNANLYSQYAHATSDYALQNPGMN---RFLGLCGEDD-DSWCS-SSTSSSDSEEEGYFLGQPIPQPRPQRFTYYTDDLSSPASALPTPQFTQRTTKSKKKKGHKGKNCIIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F2Z4V3-1", "uniprot_id": "F2Z4V3_DANRE", "id": "F2Z4V3-1", "name": "", "aln": "MHYAKCPHPMSLETTSGIWPITRAPDMDSRGAKAFGFQRSSTSDDDSGCALEEYTWVPPGLRAEQVQIYFSCLPEEKVPYVNSPGEKHRIRQLLYQLPPHDNEIRYCQSLSDEERRELHMFSMQRKKEALGRGTPKLLPRALQHN-CEHCKENINGGEMAVFASRAGPGPCWHPACFTCYTCHELLVDLIYFYHNGNIHCGRHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFSCFECETILGGQRYIMKDGRPFCCGCFESLYAEYCEACGENIGVDHAQMTYEGVHWHATDKCFCCAQCKTSLLGCPFLPKDGRIYCSKDCSLGEDVQASDSSDSAFQSARSRESRRSIRMGKSSRPTEQCQQTKLYS-ATDYRTSSLCGDNTETMCHQLERINFT--------EDNYWRERDEQEAPEDSVEDWAEHEDYMTQLLLKFGDRGVIHAE----DSRAAEPWMVKDTETNRTKPEIKMSGHNLASKKHHTDMYWAQSQDGLGDSAYGSHPGPASARKIQELEMDQGTVPGFWSEPRQWYEDSLECITSELRKADHNIGDSMDSLALSNITGASVDGDSKDRQTIYSLQNMKDQEREIEECDNISNVGTLNSSMLHRSANSLRSLNSELGHEETLGQGAREDDEEDRIPPYFGAEPPSPLNLPVLRRTKSQSQPQSRSQQVKFSDDVLEKGYYGALGLRQPPMSERTRRRTFHIEEEAAAAAERRPANRHHHKRRHSRKTRSENALHLP------SKNRGKLHVVP---QVISSNMPEPRNGILLNHSAHSQHPYRQTTSDFPQQGMVRLDQFQDFCDDDEEDDWCSTCSSSSSESEEEGFFLGQPIPKPRSQSFHYYTEDYPTRVTAL-TPPFGSRTK--LKKKGHKGKNCIIS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: *.*. .** *****************:*******.**:*:**:*******************:************:*******:**::**::** *********** ***.**: * **:* ::****:********** ****:**.*:**:**********::*:****************************************.*:****:****************************:***:**********:* *****: **.*****:**********:*:***** ******::***************:****:***:***.::**:*: * * * :*: ..*.*: :*:.::*: :.:: .:::*: * ***:.** *:**:**************:.::: : * **:* *: .: .. *.*:* . :.*****:::************************:*::***::*:* ..*: : *********:: *.::.: ******************:.* * ::*****: :* * *:*:::**:************:**:**.* * *: * : .* :******:****:** ********:::* * : :************.:::** * :. ***::*:***:**:***:* .*:* :*:. :.*..: .. :. : * . :.*:.: : : : ** :* .: .:*: *.*** .*:***:*****:*******:**.* * ***:* .: :** ** * .**. *************", "identical_positions": 527, "similar_positions": 192, "identity": "58.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2159", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24942-1", "uniprot_id": "EAA1_RAT", "id": "P24942-1", "name": "Excitatory amino acid transporter 1", "aln": "MTKSNGEEPRMGSRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVSAVIVGTILGFALR--PYKMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMYREG---KIVQVTAADAFLDLIRNMFPPNLVEACFKQFKTSYEKRSFKVPIQANETLLGAVINNVSEAMETLTRIREEMVPVPGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPLGILFLIAGKILEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRITRFVLPVGATINMDGTALYEALAAIFIAQVNNFDLNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRHELKNRD---------VEMGNSVIEENEMKKP----YQLIA--------------QDNEPE-KPVADSETKM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56564-1", "uniprot_id": "EAA1_MOUSE", "id": "P56564-1", "name": "Excitatory amino acid transporter 1", "aln": "MTKSNGEEPRMGGRMERLQQGVRKRTLLAKKKVQSLTKEDVKSYLFRNAFVLLTVTAVIVGTILGFALR--PYKMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMYREG---KIVQVTAADAFLDLIRNMFPPNLVEACFKQFKTSYEKRSFKVPIQSNETLLGAVINNVSEAMETLTRIREEMVPVPGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPLGILFLIAGKIVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRITRFVLPVGATINMDGTALYEALAAIFIAQVNNFDLNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRHELKNRD---------VEMGNSVIEENEMKKP----YQLIA--------------QDNEPE-KPVADSETKM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43003-1", "uniprot_id": "EAA1_HUMAN", "id": "P43003-1", "name": "Excitatory amino acid transporter 1", "aln": "MTKSNGEEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIVGTILGFTLR--PYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREG---KIVRVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRHELKNRD---------VEMGNSVIEENEMKKP----YQLIA--------------QDNETE-KPI-DSETKM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ARW5-1", "uniprot_id": "A0A8M3ARW5_DANRE", "id": "A0A8M3ARW5-1", "name": "Amino acid transporter", "aln": "MTQSNGETRLQRSRVQQLRDGLTERSLRAKNTVQNISSNDVKGFFMRNAFVILTVAAVIVGIILGFGLR--PYKMSYREVKYFSFPGELLMRMLQMLVLPLLVSSLITGMAALDSRASGKMGVRAVVYYTTTTIIAVFIGIVMVLIIHPGKGSKDEFTKHE---KIEQVSPADAFLDLIRNMFPPNLVQACTQQFKTQYGKRVVTVKVLVNDTVFS--LNNGTQELK-----REEVIPVLGTVNGINALGLVVFSMCFGLIIGNMKEQGQPLRDFFDCLNEAIMRLVAIIMWYAPLGIMFLIAGKIVEMDDLSEMGGQLGMYTITVIIGLLIHAVIVLPMLYFLVTRKNPFVFIAGLLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNDMEMNFGEILTISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSIGAGIVEHLSRHELRSID---------AEIGNSVLEENETKKS----YQLIS--------------QESESDNAKIPDSESKM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A6H2EJK0-1", "uniprot_id": "A0A6H2EJK0_DROME", "id": "A0A6H2EJK0-1", "name": "Amino acid transporter", "aln": "MTRPK-------------QDGGK-----------------FKAFMQENVLTMATVIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRMLKCLIVPLLVSSITSAIGGLDLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVETQTESIDKASKVLTPDTLMDLVRNMFTDNIIQSTMFQHRTEIYENTSISPAQP----------------------MENWEFKSAQREGSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAAKIIEMESIAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLATAFGTGSSSATMPLTIKCLD-NMGIDPRVTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSITATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDVSLIIAVDWLLDRFRTTINVMCDALGTILVNHLSKNDLASVDRLNAEPHELLELGPNGHEMKEXRQSSLGAYNRKRXVDMSRLWACFHILPSNDSDSDDYDDDDEEF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:.: ::* .*.:: .*.:.: ** .*:** ::** :: . . * **: *:*****:::***: *::**::**: :.:..** *.*:. **:.** .*** **.:** :* ::**:*:* : * :* ..*:::**:****. *:::: *.:*. :. *: . :* *.****:**: :* **.*:*:** *::** *.**:* :.: ::* :*:*: ****.**:**:.:. .*. * :**::**::*.. .:.:::** **: *: :*. * *.* **:**.*****:*:*:***: * *:* *:****:****************:**:**** .::. .** *:::***********************:** :*** ..*::*******:***:*** **: *::*: :*:***:::* . * *:* . * :* ::. *: ..:.: *.: ::", "identical_positions": 216, "similar_positions": 170, "identity": "37.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2165", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62725-1", "uniprot_id": "NFYC_RAT", "id": "Q62725-1", "name": "Nuclear transcription factor Y subunit gamma", "aln": "----------------------------------------------------------------------------------------------------------------MSTEGGFGSTSSSDAQQSLQSFWPRVMEEIRNLT------VKDFRVQELPLARIKKIMKLDEDVKMISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPRDELKPPKRQEEVRQSVTP------------------------------------------------------------AEPVQYYFTLAQQPTAVQVQGQQQGQQTTS-STTTIQPGQ----------IIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQ------------------------------------------------AQQAQSG-TGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQ-------------------ITQTEVQQGQQQFSQFTDGQ--------------------------------------------------------------------------------------------------------QLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQ-TPQVTGD--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13952-1", "uniprot_id": "NFYC_HUMAN", "id": "Q13952-1", "name": "Nuclear transcription factor Y subunit gamma", "aln": "----------------------------------------------------------------------------------------------------------------MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLT------VKDFRVQELPLARIKKIMKLDEDVKMISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPRDELKPPKRQEEVRQSVTP------------------------------------------------------------AEPVQYYFTLAQQPTAVQVQGQQQGQQTTS-STTTIQPGQ----------IIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQ------------------------------------------------AQQAQSG-TGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQGQRNASQGKPRRCLKETLQITQTEVQQGQQQFSQFTDGQRNSVQQARVSELTGEAEPREVKATGNSTPCTSSLPTTHPPSHRAGASCVCCSQPQQSSTSPPPSDALQWVVVEVSGTPNQLETHRELHAPLPGMTSLSPLHPSQQLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQ-APQVTGD--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70353-1", "uniprot_id": "NFYC_MOUSE", "id": "P70353-1", "name": "Nuclear transcription factor Y subunit gamma", "aln": "----------------------------------------------------------------------------------------------------------------MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLT------VKDFRVQELPLARIKKIMKLDEDVKMISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPRDELKPPKRQEEVRQSVTP------------------------------------------------------------AEPVQYYFTLAQQPTAVQVQGQQQGQQTTS-STTTIQPGQ----------IIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQ------------------------------------------------AQQTQSG-TGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQ-------------------ITQTEVQQGQQQFSQFTDGQ--------------------------------------------------------------------------------------------------------QLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQ-TPQVTGD--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3B3Q2-1", "uniprot_id": "A0A8M3B3Q2_DANRE", "id": "A0A8M3B3Q2-1", "name": "Nuclear transcription factor Y subunit gamma", "aln": "----------------------------------------------------------------------------------------------------------------MSADS-FG-AGGSDAQQSLQSFWPRVMEEIRNLT------VKDFRVQELPLARIKKIMKLDEDVKMISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPRDDLKPPKRQEEVRQSVAP------------------------------------------------------------TEPVQYYFTLAQQPSAVQVQGQQQGQQVSAPTATTLQPGQ----------IIIAQPQQGQSAPVTMQVGEGQQVQIVQAAAQGQ------------------------------------------------AQAQTAQPAGQTMQVMQQIITNTGEIQQIPVQLNTGQLQYIRLAQPVSGTQVVQGQIQTLAANTQQ-------------------LSQTEVQQGQQQFNQFTDGQ--------------------------------------------------------------------------------------------------------QLYQIQQVTMPAGQELTQPMFIQSTNQTADGQVTTQVSAD--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3V9-1", "uniprot_id": "Q9W3V9_DROME", "id": "Q9W3V9-1", "name": "Nuclear transcription factor Y subunit gamma", "aln": "-MYATNNGGTNKAPNSNATSMFDNTITVTPIKMELGQAYAKSQNSAAMQRRTPNAVVVTSSSTVSSAQQQQQQQGQQQQQTVPMASLVSNACTLVNPSMSVTVATTVASGAKEKTTKATRTQVARKPPPTIDNFWPNIVSEVHSIG------QVDAKHQVLPLARIKKIMKLDENAKMIAGEAPLLFAKACEYFIQELTMHAWVHTEESRRRTLQRSDIAQAIANYDQFDFLIDIVPREEIKPSSAQKTKDGSTSSSSGMAGAASSAASTSNTATSNAAASVAGNATATGNFVASGSTVPATTAGGLKLDTTGATNAAEVLGFSTVNSDIFSAQLQQQQQQQQQHAAQQQQQQQQQQHHQAHPQQVQIIQQGAGGQQLQYFIALPSQQAAQLVQQPQPAQNHLPINILSTQQPTQQLILTAGPNGQLTATPAPQTTAQQQTALLQNLAQQQQQHQQHQQQIQLLQQVVTPTGELTNVPIAINASHLNLLQRLQMQQQQQQQQQQQQQQQQQQQVIIPTQLLTTQQLLQLGGAPTVAHQQQQQQQQHANLTQQS-------------------------------------------------------------------------------------------------NASAVASGTPIFINSTMTGAQAAATQAQQQQSAQQQQAQTISTMSTDRTLTGGFR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02516-1", "uniprot_id": "HAP5_YEAST", "id": "Q02516-1", "name": "Transcriptional activator HAP5", "aln": "MTDRNFSPQQGQGPQESLPEGPQPSTMIQREEMNMPRQYSEQQQLQENEGEGENTRLPVSEEEFRMVQELQAIQAGHDQANLPPSGRGSLEGEDNGNSDGADGEMDEDD-EEYDVFRNVGQGLVGHYKEIMIRYWQELINEIESTNEPGSEHQDDFKSHSLPFARIRKVMKTDEDVKMISAEAPIIFAKACEIFITELTMRAWCVAERNKRRTLQKADIAEALQKSDMFDFLIDVVPRRPLPQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . : :* .::.*:.. * : : **:***:*:** **:.***:.***::****.: ** ***::** :* .:*****: *** *: : * ******:*** : ", "identical_positions": 50, "similar_positions": 35, "identity": "7.09%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2168", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P02655-1", "uniprot_id": "APOC2_HUMAN", "id": "P02655-1", "name": "Apolipoprotein C-II", "aln": "MGTRLLPALFLVLLVLGFEVQGTQQPQQDEMPSPTFLTQVKESLSSYWESAKTAAQNLYEKTYLPAVDEKLRDLYSKSTAAMSTYTGIFTDQVLSVLKGEE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QEQ1-1", "uniprot_id": "E9QEQ1_DANRE", "id": "E9QEQ1-1", "name": "Apolipoprotein C-II", "aln": "MNKILAITVFVAFLALGAESFRVPRQAEDEKGT---IAVVVDTLKSYYDQSVDTASGYVETIKGYKLEEKAKTIYSDTVRAVGTYAGIFQDQLYHILYSQDSH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. * ::*:.:*.** * . : :** : :: * ::*.**::.: :*.. *. ::** : :**.:. *:.**:*** **: :* .:: ", "identical_positions": 28, "similar_positions": 40, "identity": "27.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2179", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JZA7-1", "uniprot_id": "A0A0G2JZA7_RAT", "id": "A0A0G2JZA7-1", "name": "hyaluronoglucosaminidase", "aln": "MYAAGSRGHSPAFLQPQNGNGHRSPGYVPGKVVPFRPAPPPKNHASAKLTSRSQEAPATFAFSPEEQRTPREDRKQKRHKNTFICFAITSFSFFVTLAVILGISSKYAPDENCPDQNPRLRNWDPGQDSAKHIVIKEGDMLRLTSDATVNSIVIQDGGLLVFGDDKDGSRNITLRTRYILIQDGGALHIGAEKCRYRSKATITLYGKSDEHES--MPTFGKKFIGVEAGGTLELHGARRTSWTMLARTLHSSGLPFGSYAFEKDFSRGLNVRVIDQDTARVLEHEKFDTHEYHNESRRLQEFLRAQDPGRIVAIAVGDSAVKSLLQGTIQMIQDRLGSKLIQGLGYRQAWALVGVIDGGSSSCNESVRNYENHSTGGKALAQGEFYTLDGQKFSVTAYSEWIEGISLSGFRVDIADGVKLHLLDDVSSWGAGDRIVVASTDYSMYQAEELTLLPCPECSRFQVKVKEIPQYLHVGEIIDGIDMRAEVGLLTRNIVIQGETEDSCYADNHCQFFDYDTFGGHVMIEKNFTSVHLSYVELKHMGQQ-HLGRYPVHFHLCGDVDSKGGYRVPTSVNGLSIHHSFSRCITVHGSSGLLIKDTIGFDTLGHCFFLEDGVEQRNILFHNLGLLTKPGTLLPTDRNSSMCTVMRDGVFGNYIPVPTTDCMAVSTFWIAHPNNHLINNAAAGSQDAGIWYLFHKEPTGESSGMQLLEKPELTPLGIFYNNRVHSNFKAGLFVDKGVKTTNSSASDPREYLCLDNSARFRPHQDADPEKPRVAAVIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGKGLTFASDGSFPSDEGSSQEVSESLFVGESKNYGSQGGQNKYMGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTKSTFKKYVPTPDRYSSAIGFLMKNSWQTTPRNNVSLVKFGPQVSLNVFFGKPGPWFEDCELDGDKNSIFHDIDGSVTGYKDTYVGRMDNYLIRHPNCVSVTKWNAVVCSGTYAQVYVQTWNTPNLSMIITRDEYPSHPMVLRGINQR-AISPQYQPVVMLEKGYTIHWSGPAPRTTFLYLVNFNKDDWIRVGLCYPSNTSFQVTVGFLQRQNGSLSRIEEYEPAQSMEELQKKPSERKFYFDSGTGLLFLYLRAHSHRDGHSYCSSQGCERVKIQAATDS---KDMSNCMAKAYPQYYKKPSAVKRMPAMLTGFCQGCGTHQMVFSSDPHKSYLPVRFQSPGKAEIQRGE-PSVISVNGTDFTFRSAGAFLLIVDACSVPFRLTEKRMFLSADISHLEEYLKASIPPRSIVLLSTRGEIKQMN-ISDSFVLLGLAKPAHLYNKGSTVFLGFSGNFTPS---WTRLFTSPDVQGLGVLEQYLPLQMEEYGCS-RTSSVHRRDLELLQQALKGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5FWI3-1", "uniprot_id": "CEIP2_MOUSE", "id": "Q5FWI3-1", "name": "Cell surface hyaluronidase", "aln": "MYAAGSRGHSPAFLQPQNGNGHRSPGYVPGKVVPLRPAPPPKNHASAKLTSRSQDAPATFAFSPEEQRTPSESRKRKRHKNTFICFAITSFSFFVALAVILGISSKYAPDENCPDQNPRLRNWDPGQDSAKHIVIKEGDLFRLTSDATVDSIVIQDGGLLVFGDDKDGSKNITLRTRYILIQDGGALHIGAEKCRYRSKATITLYGKSDERES--MPIFGKKFIGVEAGGTLELHGAQRTSWTMLARTLHSSGLPFGSYAFEKDFSRGLNVRVIDQDTARVLENEKFDTHEYHNESRRLQEFLRAQEPGRIVAIAVGDSAVKSLLQGTIQMIQDRLGSKLIQGLGYRQAWALVGVIDGGSSSCNESVRNYENHSTGGKALAQGEFYTLDGQKFSVTAYSEWSQGISLSGFRVDIADGVKLHLLDDVSTWEAGDRIVVASTDYSMYQAEELTLLRCPECSRSQVKVKEIPQYLHVGEIIDGIDMRAEVGLLTRNIVIQGEMEDSCYAENHCQFFDYDTFGGHVMIEKNFTSVHLSYVELKHMGQQ-HMGRYPVHFHLCGDVDSKGGYSQPASVDGLSVHHSFSRCITVHGTSGLLIKDTIGFDTLGHCFFLEDGVEQRNILYHNLGLLTKPGTLLPTDRNSSMCTVMRDGVFGNYVPVPTTDCMAVSTFWIAHPNNHLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLEKPELTPLGIFYNNRVHSNFKAGLFVDKGVKTTNASASDPREYLCLDNSARFRPHQDADPEKPRVAAIIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGKGLTFASDGSFPSDEGSSQEVTESLFVGESRNYGFQGGQNKYMGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTKSTFKKYVPTPDRYSSAIGFLMKNSWQTTPRNNVSLVKFGPQVSLNVFFGKPGPWFEDCELDGDKNSIFHDIDGSVTGYKDTYVGRMDNYLIRHPNCVNVTKWNAVICSGTYAQVYVQTWNTPNLSMIITRDEYPSHPMVLRGINQR-AISPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKDDWIRVGLCYPANTSFQVTVGFLQRQNGSLSRIEDYEPARSMEELQKKPSERKFYFDSGTGLLFLYLRAHSHRDGHSYCSSQGCERVKIQAATDS---KDISNCMAKAYPQYYKKPSAVKRMPAMLTGLCQGCGTHQMVFTSDPHKSYLPVRFQSPGKAEIQRGD-PSIISVNGTDFTFRSAGALLLIVDACSVPFRVKEKRMFLSADVSHMEEYFKASIPPRSIVLLSTRGEIKQLN-ISDSLAVLGLAKPAHLYSKGSVVFLGFSGNFAPS---WTKLFTSPDEQGLGVLEQFLPLQMEEYGCS-RTGSVHRRDLDLLQQALKVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHN6-1", "uniprot_id": "CEIP2_HUMAN", "id": "Q9UHN6-1", "name": "Cell surface hyaluronidase CEMIP2", "aln": "MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATFAFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRLRNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYILIQDGGALHIGAEKCRYKSKATITLYGKSDEGES--MPTFGKKFIGVEAGGTLELHGARKASWTLLARTLNSSGLPFGSYTFEKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTSCNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWIEGVSLSGFRVEVVDGVKLNLLDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFLHMGEIIDGVDMRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMIMKNFTSVHLSYVELKHMGQQ-QMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNRVHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRVAALIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESLFVGESRNYGFQGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVPTPDRYSSAIGFLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEMDGDKNSIFHDIDGSVTGYKDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMTITRDEYPSNPMVLRGINQK-AAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCYPSNTSFQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFDSSTGLLFLYLKAKSHRHGHSYCSSQGCERVKIQAATDS---KDISNCMAKAYPQYYRKPSVVKRMPAMLTGLCQGCGTRQVVFTSDPHKSYLPVQFQSPDKAETQRGD-PSVISVNGTDFTFRSAGVLLLVVDPCSVPFRLTEKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLN-ISHLLVPLGLAKPAHLYDKGSTIFLGFSGNFKPS---WTKLFTSPAGQGLGVLEQFIPLQLDEYGCP-RATTVRRRDLELLKQASKAH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KPQ7-1", "uniprot_id": "CEIP2_DANRE", "id": "A3KPQ7-1", "name": "Cell surface hyaluronidase", "aln": "MQVNDGPSSHPIFVAPVNGNAQRSSGYVPGRIVPVRSPPPAKAPPPPPLKPPVPPPARPSVFNLSEDGNRREQAQNQQRKNTYICVGIFFGIFLLILILVLSLTSKDVLDENCPHQNPALRSWKPGHDLKKVVVIHSGEHYRLDSSATLYSITIQAGGSVVFADDKKGSKNITLRTRHILIEDGGALHIGAPKCRYRSLATITLVGRSDETAVTEVPGMGRKFLGVNSGGTLELHGSERMSWTFLTRTVPASGLATGDHAFQKNFSRGINLRVVDQDTAEVLVNERFDTHESQDDSKRLGELLKALPAGRIVALATGDSAVKNLVFETKQTIHDLLGSNYISDLKYRDAWALVSVIGGGNGSCTEDVREHENHDTGGKALARQDFFTVDGVGFTVTAYSEWSNGYPTTGFQVDAVDKVVLNLQDDVSSWNPGDRIVVASTDYSMYQAEEFTLLPCPNCNRKQVQIQGKPQFSHVGEILDGVDMRAEVALLSRNILIHGEMENSCYGGNWCQYFSYDTFGGHIKILGNFTSVHLSHIELKHMGQQREKGRYPLNFHRCGDVDQSGGYSNPAYVDSLSIHHSFSRCVTVHATNGLLVKDTVGYDTLGHCFFLKDGIEQRNIFFHNLGLLTRPGTILPTDRNDSMCTEITDRVYKGYIPIPANECKAVSSFWIAHPNNHLISNSAAGSQDAGIWYVFHNSSTGDSHGMISETKAELTPLGTFFNNRVHSNFKAGLFIDRKVKSTNATAADPREYLCLDNSARFRPHESSDPSRPRVAAIIDTLISFKNNDLGAWIRGGDIIIRN------------SGDGSYPKDEGSSQEVSQSLFIGESRNRGTNGGQNKYWGIGGVDGKMRTLPRNKTFPIRGFQINDGPVRIFDSTFRAFSPTADRFTMAVGFSLKNIWQLTPRNNLSALAFHPSVTLRAFFGRPGDWFEQNDLDGDKNSIFHDLDGSISGYADTYVARADNFLIRHPQCVDMPQWNGVVCSGKYSQVYIQTQAASNLSLSISRDEYPDKPMVLRGIRTKTSPSQQYQPVLMMGKSYTMHWNGPAPRETVLSLINFDQDDWALLGLCYPNETVFQITSDIYNKQNNGFEGIEDYGPVTSIADLEKRQQERKYFFDKSAGLLWLYARARHRRDGNSYCSSAGCERVKIIATIRANQKTETCNCTANAYPKYSKPASNIVPMPKPNTEPCGACGASQFAFSSDPWNSYLQTQIKSLSVKEEQDNDTQAYITVNAQRFDLSQSGFLLVTVDACSG--KVTKNSMFSSLDT-KMEQFFKTGIMKRSIVLLATRGQPASFAGVAQYLESLGSAKTPDLQNKVAIAFFGFLGQGGPSPQPWSTLLTCQGAKILGLQERFIPLSLEEYSCPPKKDSPTRMDLELLKKIS---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . .. . * *: * ***.::..*****::**.*..**.* ... :.. . .*. .*: *. :.:::***:**..* *:: * ::*.::** . *****.*** **.*.**:* * :**:.*: ** *.**: **.** ** :**.*:*.**:******::***:********* ****:* ***** *:*** :* :*:**:**::********:.: ***:*:**: :***. *.::*:*:****:*:**:*****.:* *:***** :::*:** *:*: .*****:*.****.*.*: * * *:: ***: *..* **:*****.**.**. **.*.**::***.:******: :*:*:** *:******* :* . :**:*: .* * *:* ****:* .**:***************:*** *.:*.: **::: **: *:***:**:******.:*:***:*:** *:***. * **:*.*******: * ********::******** . ****::** ***** .*** .: *:.**:*******:***.:.***:***:*:*********:**:**** ::*******:***:******.**** : * *: .*:*:*:.:* ***:********:**.*:***********:**:..**:* *: *.****** *:*************:*: **:**::*:*****************:.::*.:*****:** **:***** ***:******::* :.***:*.********::***:***:* * :****** * **:* * ******:********* ***::: ***: : **.**:: *:** :** ** *****:* : * * *:*..***:** ***: ::**********:***::** *:**.* **:*****.**.:.:**.*:***.*:***:** : ***: *:*****.:*******. : : *****:*: *.**:**.***** *.* *:**:::** :***** :* **:* . ::**..:. **:* *. *: :*::: .***::**..:***:** :*: :*.*:***** ******* *: : .: .** *:***:* : .* : ** * * .**: *..*:*** :*** .:::* . * * .: : *:**. * : .:* :*: **.** ::.:: :* * ::*:::*:.* ******:***: .: ::. : ** **...* .* : *:** *: ** *: *:*. : **: *:::**.::**.*. : : * **:**:: ", "identical_positions": 751, "similar_positions": 387, "identity": "53.8%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2184", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJT6-1", "uniprot_id": "LSG1_RAT", "id": "Q5BJT6-1", "name": "Large subunit GTPase 1 homolog", "aln": "-----MGRRRAPGGGS-LGRVLIRHQTQRS-RSHRHTDSWLHTSELNDG--------YDWGRLNLQSVTEQSSLEDFLATAELAGTEFVAEKLN-IKFVPPEARTG-------LLSFEESQRIKRLHEENRQFLCIPRRPNWDRKTSPEELKQAEKDNFLKWRRQLVRLEE-EQKLILTPFERNLDFWRQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKEIDAAKENVILINKADLLTAEQRVAWAVHFEKEGVKVIFWSALAETVHLNGDSKDEVNSVAGEANSSESEDSSLDGNEIPH--------RDLFLLSEESESDDDDSEYEDCQE---DEEEDWQTCSEEDSNPEEGQEEGGCDRDQKEHGPEDSEAQSRASPENSQMSNKSHLVSKQELLELFKKLHTGKKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMICSGILPIDQMRDHVPPVSLVCQNIPRRVLEATYGINIIKPGEDEDPY-RPPTSEELLTAYGCMRGFMTA-HGQPDQPRSARYILKDYVRGKLLYCHPPPGKDPVA------FQHQHRQLLENKIKGEELRLQPGKTQKAKQVENVVDKTFFHQENVRALTKGVQAVMGYKPGSGLVTAAAASAENVPG-----------------------KPWKKHGNRNKKEKSRRLYRHLDV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UM18-1", "uniprot_id": "LSG1_MOUSE", "id": "Q3UM18-1", "name": "Large subunit GTPase 1 homolog", "aln": "-----MGRRRAPGGGS-LGRVLIRQQTQRS-RSHRHTDSWLHTSELNDG--------YDWGRLNLQSVTEQSSLEDFLATAELAGTEFVAEKLN-IKFVPPEARTG-------LLSFEESQRIKKLHEENRQFLCIPRRPNWDRKTSPEELKQAEKDNFLKWRRQLVRLEE-EQKLILTPFERNLDFWRQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKEIDAAKENVILINKADLLTAEQRFAWAVHFEKEGVKVIFWSALAETDHLNGDLKEEVDSVAGDTNKTESESSSLDANEIPH--------RDLISLSEESASDSGDSKYEDCQE---DEEEDWQTCSEEDSVPE---EEEGCN--------ADSETQNRKNAENQQVNNDSYLVSKQELLELFKKLHTGKKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMICNGILPIDQMRDHVPPVSLVCQNIPRRVLEVTYGINIIKPREDEDPY-RPPTSEELLTAYGCMRGFMTA-HGQPDQPRSARYILKDYVGGKLLYCHPPPGKDPVA------FQHQHQQLLESKVKGGELRLQPGKGRKAKQIENVVDKTFFHQENVRALTKGVQAVMGYKPGHGLVTAAAASAENVPG-----------------------KPWKKHGNRNKKEKSRRLYKHLDV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H089-1", "uniprot_id": "LSG1_HUMAN", "id": "Q9H089-1", "name": "Large subunit GTPase 1 homolog", "aln": "-----MGRRRAPAGGS-LGRALMRHQTQRS-RSHRHTDSWLHTSELNDG--------YDWGRLNLQSVTEQSSLDDFLATAELAGTEFVAEKLN-IKFVPAEARTG-------LLSFEESQRIKKLHEENKQFLCIPRRPNWNQNTTPEELKQAEKDNFLEWRRQLVRLEE-EQKLILTPFERNLDFWRQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKEMDANKENVILINKADLLTAEQRSAWAMYFEKEDVKVIFWSALAGAIPLNGDSEEEANRDDRQSNTTKFGHSSFDQAEISHSESEHLPARDSPSLSENPTTDEDDSEYEDCPE---EEEDDWQTCSEEDGPKE-----EDCSQDWKESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKELHTGRKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPREDEDPH-RPPTSEELLTAYGYMRGFMTA-HGQPDQPRSARYILKDYVSGKLLYCHPPPGRDPVT------FQHQHQRLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVMGYKPGSGVVTASTASSENGAG-----------------------KPWKKHGNRNKKEKSRRLYKHLDM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NY89-1", "uniprot_id": "LSG1_DANRE", "id": "Q6NY89-1", "name": "Large subunit GTPase 1 homolog", "aln": "-----MGKKKTRGEGSGLGRALIKERLNAG-RGYRRNDTWLHTSELNDG--------YDWGRLNLQSVTEQSSLDDFLATAELAGTEFVAEKLN-IKFVPAEARAG-------LLSSEESRRLKKLHEENKQLLRIPRRPPWDESTSPEVLQQTEKDSFLTWRRDLARLEE-EQKLILTPFERNLDFWRQLWRVIERSDVVVQIVDARNPLLFRCPDLEKYVKEVSVHKVNMLLLNKADLLTREQRRAWARYFQKEGIRAVFWSALAEAQRLEAEERGEDAMDQEDQSDTEEETASKNATDHHE--------ENSSSPNEEKDENEQDEEEEGEDERICVDESEWQTCSEESGDED-------------------HAEENPESTATSSFYNSSRLLRKNELLEMFKSVHSGPTCKDGQITVGLVGYPNVGKSSTINTIFRNKKVSVSATPGHTKHFQTLFVEPGLCLCDCPGLVMPSFVSTKAEMICSGILPIDQMRDHVPAISLVCQNIPRNVLEGTYGINIIRPREDEDPD-RPPTYEELLMAYGYMRGFMTA-HGQPDQSRSARYVLKDYVSGKLLYCHPPPHINPED------FQPQHAKFAMRITGAEQIDGSGGKPSKVKRIENTVDKQFFHQANVRALTKGVQMVMGYKPGSGPVEAGKANTEQQAG-----------------------KPWKKHGNRNKKEKVRRLNKHLDA-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W590-1", "uniprot_id": "LSG1_DROME", "id": "Q9W590-1", "name": "Large subunit GTPase 1 homolog", "aln": "-----MGKKNKGGAPN-LGRQLIKDRFGHTQRRKVDNDTMLHTTELQDG--------YDWGRLNLSSVTEESSFQAFLRTAELAGTEFQAEKLN-ITFVNPKQRVG-------LLSKTQEQRMHQKHDEHRDQLKIPRRPKWTKETSAEELVRAENEAFLDWRRDLALLQE-DEEILMTPYEKNLEFWRQLWRVVERSDVVVQIVDARNPLLFRSADLERYVKEVEPSKMNMILVNKSDLLTEEQRRHWAEYFDSEGIRTAFYSATLVEEELKREAEECLDSFP------EVQQLRRAVEEIKQ--------------SLDSVEDALN-----------VIEQKYKTIP---------------------------ETQNDELPRLPGDKNSPRLLSRLELIEFLRNIYTGPRHTEQHVTVGMVGYPNVGKSSTINSLMTVKKVSVSATPGKTKRFQTLFLDKDILLCDCPGLVMPSFVLTKADMLLNGILPIDQMRDHVPAVNLLCERIPRHVLEDKYGIVIAKPLEGEDME-RPPHSEELLLAYGYNRGFMTS-NGQPDQARSARYVLKDYVNGRLLYAMSPPSVPQTE------YHTFPERQRRVIEESQLPGQQQRAMRINKSTSKELDNQFFSDKPTHAHVKGRTNFPNVRLAN---DGSLVAGNDPAA-----------------------KPWR-HVKKERREKLRKKFSHLDEH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53145-1", "uniprot_id": "LSG1_YEAST", "id": "P53145-1", "name": "Large subunit GTPase 1", "aln": "MPPKEAPKKWKAPKGPKPTHRKNKNKLELGRAIKYARQKENAIEYLPDGEMRFTTDKHEANWVKLRSVTQESALDEFLSTAALADKDFTADRHSNVKIIRMDSGNDSATSQGFSMTNEQRGNLNAKQRALAKDLIVPRRPEWNEGMSKFQLDRQEKEAFLEWRRKLAHLQESNEDLLLTPFERNIEVWKQLWRVVERSDLVVQIVDARNPLLFRSVDLERYVKESDDRKANLLLVNKADLLTKKQRIAWAKYFISKNISFTFYSALRANQLLEKQKEMGEDYREQDFEEADKEGFDADEKVMEK------------------------------------------------------------------------------VKILSIDQLEELFLSKAPNEPLLPPLPG----QPPLINIGLVGYPNVGKSSTINSLVGAKKVSVSSTPGKTKHFQTIKLSDSVMLCDCPGLVFPNFAYNKGELVCNGVLPIDQLRDYIGPAGLVAERIPKYYIEAIYGIHIQTKSRDEGGNGDIPTAQELLVAYARARGYMTQGYGSADEPRASRYILKDYVNGKLLYVNPPPHLEDDTPYTREECEEFNKDLYVFDRLPDTRKEQVQNAAKAKGIDIVDLARDLNQLTFSAHTGGDTQKEAKSVTHGGKQAALYNAAEDLDRDFFKMNNVEGRLSTPFHKVQNSSAGKRHNKKNKSKNAKSKVFSIENN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : :.: :. * ** :: . ::* ***::*::: ** ** **..:* *:: . :.:: . . :: : .:: : . * :**** * . : * : *:: ** ***.*. *:* ::.:::**:*:*::.*:*****:****:**************. *** **** . * *::*:**:**** :** ** :* .:.: *:** *: : . . . :: : :: : :.:*:*************::. ******:***:**:***: :. .: ********:*.*. .*.:: .*:*****:**:: . .*:.:.**: :* *** * ..*. * :*** **. **:** *..*:.*::**:***** *:*** .** . . * . : : * . * .. : .. : * :::: :: : :: ", "identical_positions": 171, "similar_positions": 156, "identity": "23.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2194", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DF06-1", "uniprot_id": "B5DF06_RAT", "id": "B5DF06-1", "name": "", "aln": "----------------------------------MHLKPYWKLQKKER-----------PLSHGNTDGDAKGRANCMKPTPSPSASPVKASSRKPFGILSPNVL-CSMSGKSPVENSLS--VKAT--------------------RNAPSAAVQQ--TEGGLPGSWAIVKPGNTKEKIAFFAAHQCSN-------------------RIGSMKIKSSWDIDGRATKRRKKSGDLKKAKLQLEMMREINSQ-CYQSEPFACGVEHCS-VHYMSDSGDGVYAARPLSVIQMVAFLEQRATALLASCTKNCTNSPAIVKISGQSRGMPPVPEPFSAPDTCEESKERENPEIGRSQSEPVRVLDMVARLESECLKHQGQREPGS-LSRNNSFRRNVGRVLLTNGSQASD-KNGEGSADTPGTQVHPLQLVSVGEGPPATDR--SAGEQAWDGTSQGCPSLPADVSFHTDSTESEPALHTAVKHCSRNDVEMAEEFD-------------ELPTDAVS--CRELVTLTSHSPEQRQEPLCVSITVCTVEKAQPSALDPLEEPLPGMLFFLSPGQDQQAHPQLSEHPAPEATEASQPPDAAEGSSAREEKDASLEPLVPAASGEGSTSQGLEAATCKKQVSQDFLETRFKIQQLLEPQQYMACLPHHIMVKIFRLLPTLSLAILKCTCRYFKSIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPYGPGYWMCCHQSQKGFPGCKLGLHDNHWLPACHSFNRAIHKKSRGSETEEEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80XI1-1", "uniprot_id": "FBX34_MOUSE", "id": "Q80XI1-1", "name": "F-box only protein 34", "aln": "----------------------------------MHLKLYWKLQKKERPLEVSRDTLRTPMSHGKANGDVKARASYMKPTVLPSASLVKASSRKPFGILSPNVL-CSMSGKSPVENSLN--VKAK--------------------KNVLSAAVHQ--SEEGLPGTWAIVKPGNTKEKIAFFAAHQYSN-------------------RIGSMKIKSSWDIDGRATKRRKKSGDLKKAKLQLEMMREINSQ-CYQSEPFVCGVEHCS-VHYMSDSGDGVCAARPLSVIQMVAFLEQKATALLASCTKNCTNSPAIVKISGQSRGIPPAPEPFSAPETCEEPKEQENPETGRSQGEPVRVLDMVARLESECLKHQGQREPGS-LSRNNSFRRNVGRVLLTNGSQASD-KSEEGSADTADPQENPLQPVSVGEEPSVTEHH-SVGEQAWDGTSQSCPSLPATVSFHMDSTDLEPGQQTAMKSCSRDDVEMVEEFD-------------ELPTDAVRRIRRELVTVTKHSPEQRQDPLCISITVCTVEKDRPAALDSLEEPLPGMLFFLSSGQDQQAHPQLREHPAPEASEASQPQDAAEGSSAGEEKDASVEPLLPAASPGGSTSQVLEAATCKKQVSQDFLETRFKIQQLLEPQQYMACLPHHIIVKIFRLLPTLSLAILKCTCRYFKSIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPYGPGYWMCCHQSQKGFPGCKLGLHDNHWLPACHSFNRAIHKKTRGSETEEEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NWN3-1", "uniprot_id": "FBX34_HUMAN", "id": "Q9NWN3-1", "name": "F-box only protein 34", "aln": "----------------------------------MHLKPYWKLQKKEHPPEVSRETQRTPMNHQKAVNDETCKASHITSSVFPSASLGKASSRKPFGILSPNVL-CSMSGKSPVESSLN--VKTK--------------------KNAPSATIHQG-EEEGPLDIWAVVKPGNTKEKIAFFASHQCSN-------------------RIGSMKIKSSWDIDGRATKRRKKSGDLKKAKVQVERMREVNSR-CYQPEPFACGIEHCS-VHYVSDSGDGVYAGRPLSVIQMVAFLEQRASALLASCSKNCTNSPAIVRFSGQSRGVPAVSESYSAPGACEEPTERGNLEVGEPQSEPVRVLDMVAKLESECLKRQGQREPGS-LSRNNSFRRNVGRVLLANSTQADEGKTKKGVLEAPDTQVNPVGSVSVDCGPSRADRCSPKEDQAWDGASQDCPPLPAGVSFHIDSAELEPGSQTAVKNSNRYDVEMTDELVGLPFSSHTYSQASELPTDAVDCMSRELVSLTSRNPDQRKESLCISITVSKVDKDQPSILNSCEDPVPGMLFFLPPGQHLSDYSQLNESTTKESSEASQLEDAAGGDSASEEKSGSAEPFVLPASSVESTLPVLEASSWKKQVSHDFLETRFKIQQLLEPQQYMAFLPHHIMVKIFRLLPTKSLVALKCTCCYFKFIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPYGPGYWMCCHRSQKGFPGCKLGLHDNHWVPACHSFNRAIHKKAKGTEAEEEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BH27-1", "uniprot_id": "A0A8M2BH27_DANRE", "id": "A0A8M2BH27-1", "name": "", "aln": "MPQKCETISYCNPTPYREPRLRASNSPAVWRLNNMHLKPYPKPQDKEIHRESVRDATR--GLHADQQGVLRKEWGVHQSCGLMGSPGNGTANRCPLGVISPNTLRCNTNSGSNVPTRVSGARKSKSLPITTFTSSLVLLSPSTGLENEGSLGIYQGEDEEGSLDIWAVIKPGNTKEKIAIFASQMCSSTCDSVIDDGSETEAIAPELRTASVKNKGCWDVDCSLPKRRRRSENPDKLKILEPLSPKLEMHNVLQQEAHCENINPCQGLAEDAVKTEGEEDEKTVSVVEMVAYLEQMANDQQIGSKSPSLRSTSTIILSKVG--------SITQPDE-QQSKAKEQLEVQEEEGESIRVLDMVAKLESQCLNRQNLRENGGELSRNNSLRRKVGRVLLAGS------------------EPYPLQSQPVSPTDPQDSGVESVPQELGSDFDKRSSQIKTLELIEITKCELDICAPEEKETSCIARLETCTAVE---------------TVNNLQSSPKDASSESSEEPLPGMLFFAKSSPQPPKAQHLPSLKSRSLNKEPSRIHKLPVDIKASFTEEIRDELASEIQNHRIFEETE----SRETCLVSQEPVPFPLR---------------RLVSHEFLETRFKIQLLLEPQQYMAFLPHHIIVKIFCLLPTESLAALKCTCHYFKCIIESYGVRPADSRWVIDPRYKDDPCKQCKKRYDRGDVSLCRWHHKPYCQSLPYGPGYWMCCRRSHKDSLGCNVGLHDNRWVPAFHSINVPIYKRSRDTDEDS--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **** * * *.** * . . . . . .:. ::.* *:*::***.* *. .. * * . :. *:. .* * : * * * . **::**********:**:: *. * .*:* *..**:* .***::* : .* *: ::: : * *.. .:: *. : : . :* :.:**::***:*** *. .... . .*.: : :* . . : * ::.. : : * . :.*.:*******:***:**::*. ** *. ******:**:******:.. : *: .*. . . . :: .. .: .. : : :. . : : : . :* . ..: : :: : :...* :. * . : *: . : *. :. *. . . . :: : : * : :: : * * **. . : **::********* ********* *****:**** **** **. ***** *** *** *.:******** ****::********:* :********* *****:***********::*:*. **::*****:*:** **:* .*:*:::.:: :. ", "identical_positions": 225, "similar_positions": 192, "identity": "28.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2196", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49750-4", "uniprot_id": "YLPM1_HUMAN", "id": "P49750-4", "name": "YLP motif-containing protein 1", "aln": "MYPNWGRYGG---------------SSHYPPPPVPPPPP-VALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPE------EDARLKQL-------QAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQY---MGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPP-PGMPPPVMPPSLPTS-------VPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP-PGVPQG--IPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNENLSDSQQEPPKSEVSEGPVEPSNWDQNVQSMETQIDKAQAVTQPVPLANKPVPAQSTFPSKTGGMEGGTAVATSSLTADNDFKPVGIGLPHSENNQDKGLPRPDNRDNRLEGNRGNSSSYRGPGQSRMEDTRDKGLVNRGRGQAISRGPGLVKQEDFRDKMMGRREDSREKMNRGEGSRDRGLVRPGSSREKVPGGLQGSQDRGAAGSRERGPPRRAGSQERGPLRRAGSRERIPPRRAGSRERGPPRGPGSRERGLGRSDFGRDRGPFRPEPGDGGEKMYPYHRDEPPRAPWNHGEERGHEEFPLDGRNAPMERERLDDWDRERYWRECERDYQDDTLELYNREDRFSAPPSRSHDGDRRGPWWDDWERDQDMDEDYNREMERDMDRDVDRISRPMDMYDRSLDNEWDRDYGRPLDEQESQFRERDIPSLPPLPPLPPLPPLDRYRDDRWREERNREHGYDRDFRDRGELRIREYPERGDTWREKRDYVPDRMDWERERLSDRWYPSDVDRHSPMAEHMPSSHHSSEMMGSDASLDSDQGLGGVMVLSQRQHEIILKAAQELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPG-SIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPP-VIKPQTS-------------AVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPG--PVPMGMPP------MSKPPP----VQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLPERSTFETEHAGQRDRYDRERDREPYFDRQSNVIADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRERRPRDDRA-----QSYRDKKDHSSSR----RGGFDRPSYDRKSDR---PVYEGPSMFGGERRTYPEERMPLPAPSLSHQPPPAPRVEKKPESKNVDDILKPPGRESRPERIVVIMRGLPGSGKTHVAKLIRDKEVEFGGPAPRVLSLDDYFITEVEKEEKDPDSGKKVKKKVMEYEYEAEMEETYRTSMFKTFKKTLDDGFFPFIILDAINDRVRHFDQFWSAAKTKGFEVYLAEMSADNQTCGKRNIHGRKLKEINKMADHWETAPRHMMRLDIRSLLQDAAIEEVEMEDFDANIEEQKEEKKDAEEEESELGYIPKSKWEMDTSEAKLDKLDGLRTGTKRKRDWEAIASRMEDYLQLPDDYDTRASEPGKKRVRWADLEEKKDADRKRAIGFVVGQTDWEKITDESGHLAEKALNRTKYI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R0I7-1", "uniprot_id": "YLPM1_MOUSE", "id": "Q9R0I7-1", "name": "YLP motif-containing protein 1", "aln": "MYPNWGRYGG---------------SSHYPPPPVPPPPPPVALPEASPGPGYSSSTAPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMIHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPSSAQPYLPPAQPGPSKPQ--------------------------------------------------LPPPPSIPSGNKTAIQQEPLESGAKNKTAEQKQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGLVTAKDVPEPIKEEAPGPAASQVAEPLAAEKPPLPPPNEEAPPPLSPEEPQSEDSEDSEDSEEDARFKQLKAIAAHWQAAAAHWQQQQQQRVGFQYQGIMQRHTQLQQILQQYQQVIQHSPHIQTMSLDVQLRHYEMQQQQFQHLFQDWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQTYLQEKVNSFQTVKSQY---LGNMAMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPTSIPP-PGMPPPVMPPSLPTS-------VPPPGMPPSLS-SGPPPVLPPPALSSAGSPPVLPPPALP--GGPPILPLPPLSSATPPPGIPP-PGAPQG--MPPQLT-APLPPASGSQNSQIPEKPRQALLPTPVSFGSTPPSPYHPPPQ----SEQVNSK-PLNK------VFSSEQGLGES-SALSQSIIAAKDTPVKSGGLLADPPKGSFLEGPRGP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------REQKEQLQKLKDFGSEPQMADHLPPPDSRLQNPS-RPGMYPPPGSYRPPPPMGKPPG-SIVRPSAPPARSSIPMTRPPVPIPPPPPPPPPPPPPPPVIKSKTS-------------SVKQERWDEDSFFGLWDTNDDQGLNSEFKRDTATIPSAPVLPPPPVHSSIPPPG--PMPMGMPP------MSKPPP----VQHTVDYGHGRDMPTNKVEQIPYGERITLRPDPLPERSTFDADHAGQRDRYDRDRDREPYFDRPSN-ITDHRDFKRDRETHRDRDRDR-VLDYERDRFDRERRPRDDRN-----QSYRDKKDHSSSR----RGGFDRPSYDRKSDR---PPYEGPPMFGGERRTYPEERMPLPAPALGHQPPPVPRVEKKPESKNVDDILKPPGRESRPERIVVIMRGLPGSGKTHVAKLIRDKEVEFGGPAPRVLSLDDYFIAEVEKEEKDPDSGKKVKKKVMEYEYEADMEETYRTSMFKTFKKTLDDGFFPFIILDAINDRVRHFDQFWSAAKTKGFEVYLAEMSADNQTCGKRNIHGRKLKEINKMAEHWEVAPRHMMRLDIRSLLQDAAIEEVEMEDFDANIEDQKEEKKDAEEEESELGYIPKSKWEMDTSEAKLDKLDGLRTGTKRKRDWEAIASRMEDYLQLPDDYETRASEPGKKRVRWADLEEKKDADRKRAIGFVVGQTDWEKITDESGHLAERALNRTKYI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F6P6X1-1", "uniprot_id": "F6P6X1_DANRE", "id": "F6P6X1-1", "name": "YLP motif-containing protein 1", "aln": "MHPSWGGFGGGHQPPPHFGPRPHQFRAAQPPPPTTAPPPQPAGAPPPGGGGFAGYGAPSFPPSN-FSSLHEQHLQQMQQLQQLHQKQLQSVLH--HSGNNSNSPSPYWQAGGAG---------------------------------------------------PAAPPNSFQAAG----PQPQPPP---------PEVKPPAPEP---------------------------------------------------------PPPAPAASKPPAASTPQVSDASAPVGDEK-----PDFSKMSMQEQQEYWYQQHLQNLQKLKNEK----------AKQNQGSFNESHASAPPPPVEPPKS--TPPPPPPKEEPPPPPPPDESQSSSVNNTGDPAEAARLQQL-------QVAAAQWQQVQHQRASFQYQALMQEHAQLQQILQQYQQVIQQPAHLQTMPFEMQLQHYEMQQQRFAPLYQEWERHFNLWLEQFQMYPHKDQLHDYEAQWRQWQEQMNSTSAHLQERVTTLRAMQHQYGSSYGMMGSYGQQSPNVQMGPNGNMNLVGPGTPSMPPPVTMDAMPAPSTQGPSQSGPVVPQGHSPSDLESISETCKTGLPPGHGVRPPGPGVRPPGPGVRPPGPGVRPPGPGVRPPGPGVRPPGPGVGPPGPGAGPGVGQPRPGVRPPGPGVGPPGPQGVRPYGPGGRPPGPGVRPSGPGSGPPGPHGRFDGPRFEGPRGPQFEQPPQQR-------FSGPPRFDAG-QRFSQPPRGNPPFPGAPARLENPPRQNTPTRFERPP-------------------------VASQQTGSGQQSSPVTGNQTKQQSAKPEAKPVPPSYTDPDKAKSPLSQSTQKENNSSAPSMTDDLVDSVDGFFIQSGPIPQTKDSDKTDADSAKQDKTKEVTTKPSAPTDAPDTTNKNSNLQPPKTSHTANGPPQQVKPPQN----KFKPDTPKETPRMLPMMNQQVPPQMARG-------------------------------------------------------------RGRGQIPMPLRGRGRARGRGQYGGPMADPNFQREIEEDSYDHQEPGNASHGEDQDRIWRDPSLDGPEEIDQEAPLEIWQPEEEHFPEEYPEDTHQDENWEEEPQDYWEEEDPYWAEQRPAMRARPPFPPGGPRRPPFHP-------------------RFMLQGPRRPPPPGSLQHNPLGPPPFRPRGGVVPRFRRGLGPWGPLPRHDMMERDLRRPPAPHEIIAREPAGPHGYEEEIDREPAWPHPRGRGIRRPPLPPHEMGRGIRR----------------------------------------------PPMRPAMPRERWHGPPPHEEENYEEEYPYGAEDDVYRR------------------PPHEYNEDYEHGDEYYGSREEWDGEQPERDYPPHRPPERVREDP-------------------------------WLEERERSFPYEEDRYREERRGPFYPDDPPYQDRDREPPFHSRSDWERPPPPPPPERGYSRSLSETDYEHKLDPLASLPAPQATDSPLDESSPSATKAVLALSQRQHEIILKAAQELKMIRELQETKKALGEVSTTESAGLPSELPAGILGLEIPPEVKSALQATNLLSETGQTFNAGLSSNQSTDFLSSTAPTASFIAKTVDYAHGRDGGS-TVERISYGERVLLRPAPAPSERSYEKELLGHRD---------PYYDRRSDPYAAR---DYDREWERDPYREKPTLDYERDRYERDRYLRDERASLGPRPTYREREREHSSRSSRDRELYNRPSYERSSYERSLEHYEHGSSSYGERRSYPDERQPPPT-SLPPSAPVAPPVEKKPEIKNAEDILKPPGRSSRPDRIVVIMRGLPGSGKSHVAKLIRDKEVECGGAPPRVLGLDDYFMTEVEKIEKDPDSGKRIKTKVLEYEYEPEMEDTYRSSMLKTFKKTLDDGFFPFIILDAINDKVKYFDQFWSAAKTKGFEVYLAEITTDQQTCAKRNIHGRTLKDISKLSGGWESAPPHMVRLDIRSLLQDAAIEDVEMEDFNPSDEPKAEVKNDDD--ETDLGYVPKSKWEMDTSEAKLDKLDGLVGGGKRKR--DAGLSGMEDFLQLPDDYATRMSEPGKKRVRWADLEEQKDVDRKRAIGFVVGQTDWEKITDESGQIAQRALNRTKYF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*.** :** : ****...*** * . .. * *::. :*: *.*. * *::**** *:*****:****:*.**: * . .*.* .** * *..**.*: ... * ***** * : *. * * **. *...*.. . * *.*. ::: ** *.*: ****:***:*** .**: .: : **: ..:*. . .... * . : ** ***:** *** .*:*.**.. : * **::** *.***:*** *::*..****.:**.*:***********:** ..*:***..::**:*******:* *:*:***.*:** **:: *******::** **: ** :*::*.::***:*.::: :: ** * *. * ** * .**:**** *:*:. . *. . **:* . ..* . .*:**. . * * : **. . . * : **. * : * . ..* ** * * *: ** .* * . . . * .: *: . *.. * . : .: * .: **. :. . **. . * .. * * :.: . * * *::*: :: . : . : * :. *: . .* ::. .. ***** * * ..: :. *:: *.* .. .* .*... .: . :. : :* : .. * .*.:. ** **: : .* : .. :.: . .. *:.. :*...* : :****.**** : .**:*.****: *** * *.. ::: : *:** **:** *: : : . *** .** *:: .:**:***::*:* **:* :**::: . *** * ::****:*.* . ** . ****:**:** * *: :* ..* .* ****** **.:********.***:**************:************ **..****.*****::**** ********::*.**:*****.:**:***:**:**********************:*::*******************:::*:***.*******.**:*.*:: ** ** **:**************:******:.. * : * *:* : *::***:******************** * **** :* * ***:******* ** ***************:**.***********************::*::*******:", "identical_positions": 593, "similar_positions": 345, "identity": "26.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2201", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZY30-1", "uniprot_id": "D3ZY30_RAT", "id": "D3ZY30-1", "name": "Class A basic helix-loop-helix protein 9", "aln": "MLRGTPGLGLRGLKRGEDSVGDLGHSCPEAGRNFGVLRR-----SLAEEEEVAGRKRERPARSKARRMAANVRERKRILDYNEAFNALRRALQHDLGGKRLSKIATLRRAIHRITALSLVLRASPAP--RWPCGHLECH--GQAAHGSSAGDSGFSVPRSVLSPAAPSLARRDTAS-----PLVPPAPRCASCSPNAHLGRPRMMAEVP------SLAQASGGSWR--RCPG---AAPVGSIQWRWG-----SGLGYQHS---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5RJB0-1", "uniprot_id": "BHA09_MOUSE", "id": "Q5RJB0-1", "name": "Class A basic helix-loop-helix protein 9", "aln": "MLRGTPGLGLGGLNRAEDFVEDLGRSCSEAGRNFGVLRRS----SLDEAEEAAGRKRERPTRSKARRMAANVRERKRILDYNEAFNALRRALQHDLGGKRLSKIATLRRAIHRITALSLVLRASPAP--RWPCGHLECH--GQAAQGSSTGNSSFSVPRSAPSPIAPSLTRRDIAS-----PLVPPTPRCASCSPHSHLGRPRVMAEVP------NLAQTSGGNWR--QCPG---APPVRPVSWRWG-----SGLGYQHS---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7RTU4-1", "uniprot_id": "BHA09_HUMAN", "id": "Q7RTU4-1", "name": "Class A basic helix-loop-helix protein 9", "aln": "MLRGAPGLGLTARKGAEDSAEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRARPVRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLVLRASPAP--RGPCGHLECH--GPAARG-DTGDTGASPP----PPAGPSLARPDAAR-----PSVPSAPRCASCPPHAPLARPSAVAEGP------GLAQASGGSWR--RCPG---ASSAGPPPWPRGYLRSAPGMGHPRS---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KNX5-1", "uniprot_id": "BHA09_DANRE", "id": "A3KNX5-1", "name": "Class A basic helix-loop-helix protein 9", "aln": "-MTPVSVCRFSMASRGSFTGSEFSEEEPDGSLQESELDSSDGLGGLNEPEERLIKKRSRPVRSKARRVAANVRERKRILDYNQAFNALRVALHHDLSGKRLSKIATLQRAINRISALSVFLTNNPPVGVAKPCGHLECQPGGLWAEAEPSMQNFLTWHQPLNQHLQTSIHRLSSEQHVFTGPACPPSPHYPCFSPDTQLYPAASVPSPPRYGRIGDVGAYQQGVWGGNHADGYGESLQTLPLPWHMG---YLQDAGLQHCPNTLCYTQCKTVRAL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. : . .. ::. .: . : . * . * ** ::* **.******:**************:****** **:***.**********:***:**:***:.* .*. *******: * *.. : :. : .*: * . * *.:*: .. .*.: * . :.. * .:. . * * :. * : . . * * . * :. ", "identical_positions": 81, "similar_positions": 64, "identity": "29.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2202", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RYM9-1", "uniprot_id": "B2RYM9_RAT", "id": "B2RYM9-1", "name": "", "aln": "---------------------------------------------------------------------MGRWALDVAFVWKAALTLGLVLLYYCFSIGITFYNKWLTKS-----FHFPLFMTMLHLAVIFLFSALSRALVQCSSH---RARVVLSWTDYLRRVAPTALATALDVGLSNWSFLYITVSLYTMTKSSAVLFILIFSLIFKLEELRAALVLVVLLIAGGLFMFTYKSTQFN---------VEGFALVLGASFIGGIRWTLTQMLLQ-----------------------------KADLGLQN-------------PIDTMFHLQPLMFLGLFPLFAVFEG-LHLSTSEKIFRFQDPG----------LLLWVLGSLLLGGILAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAAHLLGDQIS-LLNWLGFALCLSGISLHVALKALHSRG-----------------------------------------------------------DGGPKP-----RKGLGSSADLELLLQSSQ--------------------------------QEE-DNGEEEYFMTQGQQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCX2-1", "uniprot_id": "S35H1_MOUSE", "id": "Q8VCX2-1", "name": "Solute carrier family 35 member H1", "aln": "---------------------------------------------------------------------MGRWALDVAFVWKAALTLGLVLLYYCFSIGITFYNKWLTKS-----FHFPLFMTMLHLAVIFLFSALSRALVQCSSH---KARVVLSWTDYLRRVAPTALATALDVGLSNWSFLYITVSLYTMTKSSAVLFILIFSLIFKLEELRAALVLVVLLIAGGLFMFTYKSTQFN---------VEGFALVLGASFIGGIRWTLTQILLQ-----------------------------KADLGLQN-------------PIDTMFHLQPLMFLGLFPLFAIFEG-LHLSTSEKIFRFQDTG----------LLLWVLGSLLLGGILAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAAHLLGDQIS-LLNWLGFALCLSGISLHVALKALHSRG-----------------------------------------------------------DGGPKP-----LKSLGSSADLELLLRSSQ--------------------------------QEE-EDGEEEYFVTQGQQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQQ7-1", "uniprot_id": "S35H1_HUMAN", "id": "Q9NQQ7-1", "name": "Solute carrier family 35 member H1", "aln": "---------------------------------------------------------------------MGRWALDVAFLWKAVLTLGLVLLYYCFSIGITFYNKWLTKS-----FHFPLFMTMLHLAVIFLFSALSRALVQCSSH---RARVVLSWADYLRRVAPTALATALDVGLSNWSFLYVTVSLYTMTKSSAVLFILIFSLIFKLEELRAALVLVVLLIAGGLFMFTYKSTQFN---------VEGFALVLGASFIGGIRWTLTQMLLQ-----------------------------KAELGLQN-------------PIDTMFHLQPLMFLGLFPLFAVFEG-LHLSTSEKIFRFQDTG----------LLLRVLGSLFLGGILAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAAHLLGDQIS-LLNWLGFALCLSGISLHVALKALHSRG-----------------------------------------------------------DGGPKA-----LKGLGSSPDLELLLRSSQ--------------------------------REEGDNEEEEYFVAQGQQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IIX0-1", "uniprot_id": "A0AC58IIX0_DANRE", "id": "A0AC58IIX0-1", "name": "Collagen alpha-1(XX) chain", "aln": "------------------------------------------------------------------------MACPTHFLCKALRTVGLVLFYYAFSIGITFYNKWLMKD-----FHFPLFMTLVHLTIIFCLSTLTRSAMQCWTG---KPRVTLPWKVYLSKVAPTALATTLDIGLSNWSFLFITISLYTMTKSSAVLFILFFSLLFKLEEPNPFLILVVVLISSGLFMFTLKSTQFN---------LEGFIMVLLASFIGGIRWTLTQLLMQ-----------------------------KAELGLQN-------------PIDTMYHLQPLMFLGLFPLFLLNEG-LSVSTTEKLFRVSELS----------HLLYSLVTLSVGGMLAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAVEFLGDKMS-TVNWLGFAVCLSGISLHIGLKTYRNKGFLIGTNTFTMAHISPLVLPERMTIFLVTVLLILVSEVQTQGRLKLTVLSEDRLQMKWKEAEGPVQGYKVRVRPITEVPQPELMLTTTRGRATVAGLDSRQEYLLQVMAINGTQEKLIAKRRFTIDGLREEELIRSGNREQKKKTPAIGSGSGEVDDVTEALEGLPTVLYREPTTTEPSVVPELEPEADQGTKEKKKKKDKNRSKAEDRIDQEENEGKSAKEEDSDTSKLRKTTPTQPGTAVSTRKPFECSAEAQAELVLLVDGSWSIGRTNFRKVREFLQGLAVPFHIGPEGVQIALSQYSGDPRTEWHLNNFTSKEPLLEAVRNFRYKGGNTFTGQALIHALENNLKEEVGARPNTPQFLLLLTDGKSQDDAIAAANRLKNAGVEIIAIGVKNADEAELRQVASEPLELNVYKVNDFPLLSKLVGKLARILCGKIEDRIKAKRMEHPTQEPVLSFPSPTDLQYVGLGSRELRLRWTVPSRNPQQYRVVYHTAEGQSLNELVVNGTESTTLLTGLSSQTQYHLSIFPVYENKVGSALRGTFTTLPLAIPEALEVTASSASSLRVRWQPAAGATQYMALYSALNDGEPDDAKEVKFGPAQTDVELVDLIPSTDYSVTLYALYDEDPSDPITAIGTTFPLPSPLSLQFPMVSHSTLMVTWVPGAVDVPAHRIIYSTNHGSDVKQVEVRGVNTVLLQNLSSLSRYLVSVHSLYEKGLSSPVTANVTTLRVPAPSDLRVTNFTGSEITVRWEAAADDVVFYLIKWISLNGGDLSQLMINGKGEGAILEKVEEDKEYQISLSASYADGAQSEAVAIRYSTLSGGGPSSLSISEETAVSMLVTWVHPNAHVQQYRVSFTPLNGDARENTVSLAGSERRILLQNLLPDTRYSVLVTAEYRSREGGSASAQGKTTSLRVSSVSVVRSDHSSICVSWRPVPAVSGYRIVIQALREKQTKEEMVDASSSSHCFSELQPETVYRISVHSRLGAVEGAAVTILHPTATAPVRVQVPPGLHPIQREVCPEMTVRNYVLKGFDMMEAFGLTQRAHSTIEGVAAEPFIFSTLPSYTLYRDVQLTQSTGFIHPAGFSPEHTISMVFRLLQDSPREPFALWQLTDNDFQPKMGVVLDPEKKVLLYFSLDYKGEIQELTFDQPQVHSIFYGSFHKIHLSVSQVSVSLSVDCQRVGERPARPLGTLPTDGFEMLGKLVKTRGPHSGSAAFQLQSFEIVCNTTWASEDSCCDLPSQRDEESCPAPAYACTCTTDVPGSPGDTGPSGKPGVRGEKGEKGEVGQKGEVGPPGKSGPEGGFGALGPAGPRGIAVMGKMGPPGARGEKGDIGRPGSQGLPGPPGQKGGEGNPGPKGTRGVEGNIGPPGITGPRGLQGMPGHPGPVGDRGPLGPVGPTGLPGSKGERGEKGEPQSLAMIYQLVSQACEKLVHNEVLKMDAFLNELNRKPVPIQEPVAPPGEPGIPGGRGAPGPRGPQGRLGSRGMPGKPGYPGEQGRRGMAGEKGSPGANAVGPQGMKGFGGPPGEAKIGEPGPKGEDGKAGPTGIPGAAGQQGEMGPSGVCDSSGCYQGPPAEDPYLGYRP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZP2-1", "uniprot_id": "Q9VZP2_DROME", "id": "Q9VZP2-1", "name": "Sugar phosphate transporter domain-containing protein", "aln": "MVAAKYERLNTSGEAAGNGNGNASDAEDEEIELHLAQKTQLGNGHRLRQSNFKYASGKCGSGEAPCTNETATLAQENMMMQMAVGTLAIIFLYLALSISLTFYQTDINRQ-----MPFPLAIVTYHLVVKFLLAAAARRIYRMRVG---RSRVQLDWRLALRKMAPTGVASAIDIGFSNWGLALVPISLYTMTKSSTIVFILLFAIAFGLEKKSWYLVSIVGLIGTGLLMFTYKSTDFN---------ALGFFFILFASLSSGLRWSFAQFIMQ-----------------------------KSKLGLHN-------------PIDMIYYMQPWMIASLVPLVIGIEG-AGLIAVIEDLHNHTSN----------EITWAIARISAGALLAFLMEFSEFLVLCKTSSLTLSIAGIFKDICQLALAVTIRKDHLS-VINYIGLIICLAGIVCHLLHKYSNMKE---------------------------------------------------------------------------MQRQQELQLDNDQ-----------------------------------EESSPGEYKFNDGSAIVGVHVKS---------------HSTLTVPLLEQTDSEDESGASNKQNASDVIFDVLKRRDMQR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03697-1", "uniprot_id": "YMD8_YEAST", "id": "Q03697-1", "name": "Putative nucleotide-sugar transporter YMD8", "aln": "--------------------------------------------------------------------------------MNRTVFLAFVFGWYFCSIALSIYNRWMFDPKDGLGIGYPVLVTTFHQATLWLLSGIYIKLRHKPVKNVLRKNNGFNWSFFLKFLLPTAVASAGDIGLSNVSFQYVPLTIYTIIKSSSIAFVLLFGCIFKLEKFHWKLALSVIIMFVGVALMVFKPSDSTSTKNDQALVIFGSFLVLASSCLSGLRWVYTQLMLRNNPIQTNTAAAVEESDGALFTENEDNVDNEPVVNLANNKMLENFGESKPHPIHTIHQLAPIMGITLLLTSLLVEKPFPGIFSSSIFRLDTSNGGVGTETTVLSIVRGIVLLILPGFAVFLLTICEFSILEQTPVLTVSIVGIVKELLTVIFGIIILSERLSGFYNWLGMLIIMADVCYYNYFRYKQDLL----------------------------------------------------------------------------QKYHSVSTQDNR-----------------------------------NELKGFQDFEQLGSKKIAP--------------------YSISVDLTNQEYELDMIAQNVSRSSQQV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.::: : **.:::*: : : :*: :. * . : :: : : . : * * : **.:*:: *:*:** .: :.:::**: ***:: *:*:*. * **: * * :: *: ::. *.:: . * ::* :* .*:** :*:::: :. :.* * **. :. : * * *. * . :: . : : : .: .* : :.** :: :*. **:**.**.*:: : :. : :::* *::*: : ::.: : : . .: : : : *. ", "identical_positions": 59, "similar_positions": 121, "identity": "2.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2207", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2W7-1", "uniprot_id": "A0A0G2K2W7_RAT", "id": "A0A0G2K2W7-1", "name": "", "aln": "-------MADEQEIMCKLESIKEIRNFRNKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALR-MTLGLQRLPDLCEEE-EKLSLDYFEK--QKAEWQTE--------------------------------------------------------------------------PQEPPIPESLAAAAAAA-------------------QQLQVARKQDTRQTATFR--------QQPPPMKACLSCHQQIHRNAPICPLCKAKSRSRNPKKPKRKQDE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQZ6-1", "uniprot_id": "ZC4H2_HUMAN", "id": "Q9NQZ6-1", "name": "Zinc finger C4H2 domain-containing protein", "aln": "-------MADEQEIMCKLESIKEIR---NKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALR-MTLGLQRLPDLCEEE-EKLSLDYFEK--QKAEWQTE--------------------------------------------------------------------------PQEPPIPESLAAAAAAA-------------------QQLQVARKQDTRQTATFR--------QQPPPMKACLSCHQQIHRNAPICPLCKAKSRSRNPKKPKRKQDE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q68FG0-1", "uniprot_id": "ZC4H2_MOUSE", "id": "Q68FG0-1", "name": "Zinc finger C4H2 domain-containing protein", "aln": "-------MADEQEIMCKLESIKEIR---NKTLQMEKIKARLKAEFEALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINVMENTIKQSENDLNKLLESTRRLHDEYKPLKEHVDALR-MTLGLQRLPDLCEEE-EKLSLDYFEK--QKAEWQTE--------------------------------------------------------------------------PQEPPIPESLAAAAAAA-------------------QQLQVARKQDTRQTATFR--------QQPPPMKACLSCHQQIHRNAPICPLCKAKSRSRNPKKPKRKQDE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7T3I0-1", "uniprot_id": "ZC4H2_DANRE", "id": "Q7T3I0-1", "name": "Zinc finger C4H2 domain-containing protein", "aln": "-------MADEQEIMCKLENIKEIR---NKTIQMEKIKSRLRTEFEALESEEKHLREYKQEMDLLLQEKMAHVEELRLIHADINVMENTIKQSESDLNKLLESTRRLHDEYKPLKEHVDALR-MTLGLQRLPDLSQEE-EKLSLDYFEK--QKAEWQTE--------------------------------------------------------------------------PQEPPIPESLAAAAAAA-------------------QQLQAARKQDARQTATFR--------QQPPPMKACLSCHQQIHRNAPICPLCKAKSRSRNPKKPKRKPDE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VX94-1", "uniprot_id": "Q9VX94_DROME", "id": "Q9VX94-1", "name": "C4H2-type domain-containing protein", "aln": "MATSEISSSNERHYYAKLEAIKDIR---DKTLSLEKLKVRIIKEVKLSDDEEKCLEEYRKEMEHLLEEKMSHVEELRQIHADINDMENIIKQTKENQTRSFDMANRVYEEYLALKYQIDHMRRDYLGLSPLRDLHEEEGSPISKDRFQTNFLKVAAQSAAAAAAAAAAAASVNQNSSLARPHARHPLMPEATVTALPSGGGQGGVGGGGAAGGGGGSVGGGGGGGGNPGHAFMPPAPPGAGSAAAAAAAAAVRLGKGDFSAPPPPPPPSNRLQQSPSIGIGHHPSFRSDFNVNLRQQPPPMKSCLSCHQQIHRNAPICPLCKAKSRSRNPKKPKKKNN-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*:. .*** **:** :**:.:**:* *: *.: :.**: *.**::**: **:***:****** ****** *** ***::.: .: :: :.*:::** .** ::* :* ***. * ** :** . :* * *:. *. *: * ** . * ******* ::** : . . : .:** *******:*******************************:* : ", "identical_positions": 119, "similar_positions": 60, "identity": "35.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2209", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AFK4-1", "uniprot_id": "A2AFK4_MOUSE", "id": "A2AFK4-1", "name": "Mitochondrial ribosome-associated GTPase 2", "aln": "MVSTRLVLARTCTVFEGVLKWAPSTRAVLRPSHLLLQ-ASCRLLSVGIVDHAKHREPSGKKVLSEKKLKRHFVDHRRVLVRGGSGGSGMSCFHSEPRKEFGGPDGGDGGNGGHIILRVDQQVKSLSSVLSQYQGFSGEDGGSKNCSGRGGATLYIQVPVGTLVKEGDKIVADLSNLGDEYVAALGGAGGKGNRFFLANDNRAPVTCTPGQPGQERVLYLELKTMAHAGMVGFPNAGKSSLLRAISNAKPAVASYPFTTLNPHVGIVHYEGHQQVAVADIPGIIRGAHQNKGLGLSFLRHIERCRFFLFVVDLTLPEPWTQVDDLKYELEKFEEGLSERSHVIIANKIDLPQARARLPQLQARLGQEAIGLSALTGENLEQLLLHLKELHDAHIEAELEQGRQPLRW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4K7-1", "uniprot_id": "MTG2_HUMAN", "id": "Q9H4K7-1", "name": "Mitochondrial ribosome-associated GTPase 2", "aln": "MAPARCFSARLRTVFQGVGHWALSTWAGLKPSRLLPQRASPRLLSVGRADLAKHQELPGKKLLSEKKLKRYFVDYRRVLVCGGNGGAGASCFHSEPRKEFGGPDGGDGGNGGHVILRVDQQVKSLSSVLSRYQGFSGEDGGSKNCFGRSGAVLYIRVPVGTLVKEGGRVVADLSCVGDEYIAALGGAGGKGNRFFLANNNRAPVTCTPGQPGQQRVLHLELKTVAHAGMVGFPNAGKSSLLRAISNARPAVASYPFTTLKPHVGIVHYEGHLQIAVADIPGIIRGAHQNRGLGSAFLRHIERCRFLLFVVDLSQPEPWTQVDDLKYELEMYEKGLSARPHAIVANKIDLPEAQANLSQLRDHLGQEVIVLSALTGENLEQLLLHLKVLYDAYAEAELGQGRQPLRW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QCB3-1", "uniprot_id": "E9QCB3_DANRE", "id": "E9QCB3-1", "name": "", "aln": "------MFVRLKILQR-----------------------SGRTVREALLQREKHTHTLEER-LSEKKLSRCFVDQRRVRLQAGSGGKGASSFHSEPRKEWGGPDGGDGGAGGHIIIRVNRQVKSLSSVSTVYRGRDGEAGGSKNCFGRNANPTYISVPVGTVVREQGVVLADLSQQDQQVTVAYGGAGGKGNRSFLTNENRAPMRATEGQQGQQREIQLELRTMAHAALVGFPNVGKSSLLRAISKARPAVAAYPFTTLNPHVGIVEYRDHTQVAVADIPGLIPGAHLNRGLGLSFLRHIERCRVLLYVLDMSSPEPWEQFQQLCFELDQYRPLFSQRPHAIVANKMDLPESRANLEALRERISQTVIPVSALTRGNTGELILHLREMYDSYPQAETLP-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .* : . * * : . : ** . :: ******.* *** *** : .*.** * *.********:********* ***:*:**::******** : *:* .** ****** **.. ** *****:*:* . ::**** .:: .* ********* **:*:****: .* ** **:* : ***:*:***.:*****.**********:*:****:******:******.*..* *:*******:* *** *:*** :*********.:*:*:*:: **** *.::* :**: :. :* *.*.*:***:***:::*.* *: ::.* .* :**** * :*:***: ::*:: :** ", "identical_positions": 206, "similar_positions": 92, "identity": "50.74%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-221", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IFV4-1", "uniprot_id": "K1C13_RAT", "id": "Q6IFV4-1", "name": "Keratin, type I cytoskeletal 13", "aln": "---------------MSCRFQSSSMSYGGG-------------FGA----GSCQLGGG-RNISTCSSRFVT------------GGSSGGYGG-----GMS----CGFGGGAGGG--------YGGGFGGGFGGSCGGGFGGGFG--------DFGSVDGGLLSGNEKITMQNLNDRLASYLEKVRALEAANADLEVKIRDWHLKQ---SPTSPERDYSAYYKTIEELRIKILEATTDNNRIVLEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLAKTDLEMQIESLNEELAYLKKNHEEEMKEFSNQAVGQ-VNVEMDATPGIDLTRVLAEMREQYEALAEKNRRDAEAWFQAKSAELNKEVSSNAAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLESTLAETECRYALQLQQIQALISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMTG--------FNTGG----------NSTTTSNTSTSPSTSGR--PDFRKY-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08730-1", "uniprot_id": "K1C13_MOUSE", "id": "P08730-1", "name": "Keratin, type I cytoskeletal 13", "aln": "---------------MSCRFQSSSMSYGGG-------------FGA----GSCQLGGG-RNISSCSSRFVT------------GGSAGGYGG-----GMS----CGFGGGAGGG--------FGGGFGGGFGGSYGGGFGGGFG--------DFGGVDGGLLSGNEKITMQNLNDRLASYLDKVRALEAANADLEVKIRDWHLKQ---SPASPERDYSAYYKTIEELRIKILEATTDNNRIILEIDNARLAADDFRLKYENELTLRQSVEADINGLRRVLDELTLAKTDLEMQIESLNEELAYLKKNHEEEMKEFSNQVVGQ-VNVEMDATPGIDLTRVLAEMREQYEALAEKNRRDAEEWFQTKSAELNKEVSSNAEMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLESTLAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMTG--------FNSGG----------NNTTTSNGSPS-SNSGR--PDFRKY-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13646-1", "uniprot_id": "K1C13_HUMAN", "id": "P13646-1", "name": "Keratin, type I cytoskeletal 13", "aln": "---------------MSLRLQSSSASYGGG-------------FGG----GSCQLGGG-RGVSTCSTRFVS------------GGSAGGYGG-----GVS----CGFGGGAGSG--------FGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQ---SPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQ-VNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHTKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMIG--------FPSSAGSVSPRSTSVTTTSSASVTTTSNASGRRTSDVRRP-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19012-1", "uniprot_id": "K1C15_HUMAN", "id": "P19012-1", "name": "Keratin, type I cytoskeletal 15", "aln": "--------------MTTTFLQTSSSTFGGGSTRGGSLLAGGGGFGG----GSLSGGGGSRSISASSARFVS------------SGSGGGYGG-----GMRV---CGFGGGAGSV--------FGGGFGGGVGGGFGGGFGGGDG---------------GLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQ---TPTSPECDYSQYFKTIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQ-VNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMAG--------IAIREAS-SGGGGSSS---NFHINVEESVDGQVVSSHKREI----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61414-1", "uniprot_id": "K1C15_MOUSE", "id": "Q61414-1", "name": "Keratin, type I cytoskeletal 15", "aln": "--------------MATTFLQTSS-TFGGSSTRGASLRAGGGSFGG----GSLYGGGGSRSISASSARFVS------------SGAGGGFGG-----GMS----CGFGGG------------FGGGFGGGFGGGFG-DFGGGDG---------------GLLSGNEKVTMQNLNDRLASYLDKVRALEQANTELEVKIRDWYQKQ---SPASPDRDYSHYFKTMEEIRDKILAATIDNSRVVLEIDNARLAADDFRLKYENELTLRQGVEADINGLRRVLDELTLARTDLEMQIEQLNEELAYLKKNHEEEMKEFSSQLAGQ-VNVEMDAAPGVDLTRMLAEMREQYEAIAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTLQGLEIELQSQLSMKAGLENSLAEVECRYATQLQQIQGVITGLETQLSELRCEMEAQNQEYNMLLDIKTRLEQEIATYRNLLEGQDAKMAG--------IGVREGS-SGGGGSSSSSSNFHISVEESVDGKVVSSRKREI----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63279-1", "uniprot_id": "K1C19_RAT", "id": "Q63279-1", "name": "Keratin, type I cytoskeletal 19", "aln": "-------------MTSYSYRQSSAMSSYGG-------------MGG----GPVRFGSG----GVFRAPSIH------------GGS-GGRGV-----SVSS---TRIVSS------------SSGGYVGGRGGSFSGALTVTDG----------------LLGGNEKITMQNLNDRLASYLDKVRALEQANGELEVKIRDWYQKQ---GPG-PFRDYSQYFKTIEDLRDKILGATIENSKIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDLEMQIENLKEELAYLKKNHEEEISALRSQVGGQ-VSVEVDSTPGIDLAKILSEMRSQYEAMAEKNRKDAEAWYLTQIDELNTQVAVHTTQIQINKTEVTELRRKVQDLEIELQSQLSMKAALEGTVAEIEARYGAQLSHIQGVISSIEVQLSNVRADTERQNQEYQQLMDIKSRLEQEIATYRSLLEGQEAHYNS--------LSIAKAL--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19001-1", "uniprot_id": "K1C19_MOUSE", "id": "P19001-1", "name": "Keratin, type I cytoskeletal 19", "aln": "-------------MTSYSYRQTSAMSSFGG-------------TGG----GSVRIGSG----GVFRAPSIH------------GGS-GGRGV-----SVSS---TRFVTS------------SSGSYGGVRGGSFSGTLAVSDG----------------LLSGNEKITMQNLNDRLASYLDKVRALEQANGELEVKIRDWYQKQ---GPG-PSRDYNHYFKTIEDLRDKILGATIDNSKIVLQIDNARLAADDFRTKFETEHALRLSVEADINGLRRVLDELTLARTDLEMQIESLKEELAYLKKNHEEEITALRSQVGGQ-VSVEVDSTPGVDLAKILSEMRSQYEIMAEKNRKDAEATYLARIEELNTQVAVHSEQIQISKTEVTDLRRTLQGLEIELQSQLSMKAALEGTLAETEARYGVQLSQIQSVISGFEAQLSDVRADIERQNQEYKQLMDIKSRLEQEIATYRSLLEGQEAHYNN--------LPTPKAI--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08727-1", "uniprot_id": "K1C19_HUMAN", "id": "P08727-1", "name": "Keratin, type I cytoskeletal 19", "aln": "-------------MTSYSYRQSSATSSFGG-------------LGG----GSVRFGPG----VAFRAPSIH------------GGS-GGRGV-----SVSS---ARFVSS------------SSS---GAYGGGYGGVLTASDG----------------LLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQ---GPG-PSRDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQ-VSVEVDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIATYRSLLEGQEDHYNN--------LSASKVL--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IFV1-1", "uniprot_id": "K1C14_RAT", "id": "Q6IFV1-1", "name": "Keratin, type I cytoskeletal 14", "aln": "-------------MATCSRQFTSSSSMKGSC-----------GIGG----GSSRMSSVLAGGSCRAPSTYG-GMS----RFSSAGAYAVGSGYGGGFSSSS-FGGGFGGGIGGGIGGGLGGGIGGGFGGGIGGGFGGGIGSGFGGGL----------GDGLLVGSEKVTMQNLNDRLATYLDKVRALEEANSDLEVKIRDWYQRQ---RPT-EIKDYSPYFKTIEDLKSKILAATVDNANVLLQIDNARLAADDFRTKFETEQSLRINVESDINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEEEMASMRGQVGGD-VNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENNLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLSSAQFSSSSQFSSGSQSSRDVTSTNRQ---IRTKVMDVHDGKVVSTHEQVLRTKN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61781-1", "uniprot_id": "K1C14_MOUSE", "id": "Q61781-1", "name": "Keratin, type I cytoskeletal 14", "aln": "-------------MATCSRQFTSSSSMKGSC-----------GIGG----GSSRMSSILAGGSCRAPSTYG-GMSVTSSRFSSGGACGIGGGYGGSFSSSS-FGGGLGSGFGGRFDG-----FGGGFGGGLGGGFGGGLGGGLGGGI----------GDGLLVGSEKVTMQNLNDRLATYLDKVRALEEANTELEVKIRDWYQRQ---RPT-EIKDYSPYFKTIEDLKSKILAATVDNANVLLQIDNARLAADDFRTKFETEQSLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEEEMASMRGQVGGD-VNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEEWFFSKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENNLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLSSSQFSSSSQFSSGSQSSRDVTSTNRQ---IRTKVMDVHDGKVVSTHEQVLRTKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02533-1", "uniprot_id": "K1C14_HUMAN", "id": "P02533-1", "name": "Keratin, type I cytoskeletal 14", "aln": "-------------MTTCSRQFTSSSSMKGSC-----------GIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGACGLGGGYGGGFSSSS-S--SFGSGFG------------GGYGGGLGAGLGGGFGGGFAG------------GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQ---RPA-EIKDYSPYFKTIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGD-VNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLSS------SQFSSGSQSSRDVTSSSRQ---IRTKVMDVHDGKVVSTHEQVLRTKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z2K1-1", "uniprot_id": "K1C16_MOUSE", "id": "Q9Z2K1-1", "name": "Keratin, type I cytoskeletal 16", "aln": "-------------MATCSRQFTSSSSMKGSC-----------GIGG----GSSRMSSILAGGSCRAPSTCG-GMSVTSSRFSSGGVCGIGGGYGGSFSSSS-FGGGLGSGFG------------GRF-DGFGGGFGAGLGGGLGGGI----------GDGLLVGSEKVTMQNLNDRLATYLDKVRALEEANRDLEVKIRDWYQRQ---RPT-EIKDYSPYFKTIEDLKSKIIIATQENAQFTLQIDNARLAADDFRTKYENELFLRQSVEGDINGLRKVLDELTLSRADLEMQIENLREELAFLKKNHEEEMLALRGQTGGD-VNVEMDAAPGVDLSRILNEMRDQYEQMAEKNRRDVEAWFLRKTEELNKEVASNSDLIQSNRSEVAELRRVFQGLEIELQSQLSMKASLENSLEETKGRYCMQLSQIQGLISSVEEQLAQLRCEMEQQSQEYNILLDVKTRLEQEIATYRRLLDGENIHSSS------QHSSGQSYSSREVFSSSS----RQPRSILKEQGSTSFSQSQSQSSRD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08779-1", "uniprot_id": "K1C16_HUMAN", "id": "P08779-1", "name": "Keratin, type I cytoskeletal 16", "aln": "-------------MTTCSRQFTSSSSMKGSC-----------GIGGGIGGGSSRISSVLAGGSCRAPSTYG-GGLSVSSRFSSGGACGLGGGYGGGFSSSSSFGSGFGGGYG------------GGLGAGFGGGLGAGFGGGFAG------------GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQ---RPS-EIKDYSPYFKTIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGD-VNVEMDAAPGVDLSRILNEMRDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRRLLEGEDAHLSS------QQASGQSYSSREVFTSSSSSSSRQTRPILKEQSSSSFSQGQSS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IFU8-1", "uniprot_id": "K1C17_RAT", "id": "Q6IFU8-1", "name": "Keratin, type I cytoskeletal 17", "aln": "-------------MTTTIRQFTSSSSIKGSS-----------GLGG----GSSRTS-------CRLSGSLG------------AGSCRLG--------SAS----GLGSALGG-----------NSYSSCYSFGTGSGYGGNFGG------------VDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQKQ---APG-PARDYSAYYQTIEDLKNKILVATVDNASILLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGE-INVEMDAAPGVDLSRILSEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGSLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLT-------QYKPKEPVTTRQVR----------TIVEEVQDGKVISSREQVHQTTR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QWL7-1", "uniprot_id": "K1C17_MOUSE", "id": "Q9QWL7-1", "name": "Keratin, type I cytoskeletal 17", "aln": "-------------MTTTIRQFTSSSSIKGSS-----------GLGG----GSSRTS-------CRLSGSLG------------AGSCRLG--------SAS----GLGSALGS-----------NSYSSCYSFGTGSGYGGNFGG------------VDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQKQ---APG-PARDYSAYYHTIEDLKNKILVATVDNASILLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGE-INVEMDAAPGVDLSRILSEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGSLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLT-------QYKPKEPVTTRQVR----------TIVEEVQDGKVISSREQVHQTTR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04695-1", "uniprot_id": "K1C17_HUMAN", "id": "Q04695-1", "name": "Keratin, type I cytoskeletal 17", "aln": "-------------MTTSIRQFTSSSSIKGSS-----------GLGG----GSSRTS-------CRLSGGLG------------AGSCRLG--------SAG----GLGSTLGG-----------SSYSSCYSFGSGGGYGSSFGG------------VDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQ---APG-PARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGE-INVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLT-------QYK-KEPVTTRQVR----------TIVEEVQDGKVISSREQVHQTTR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IFU7-1", "uniprot_id": "K1C42_RAT", "id": "Q6IFU7-1", "name": "Keratin, type I cytoskeletal 42", "aln": "-----------MASTTSIRQFSTSGSVKGLC-----------APGM----GFSRMSSVRIGGACRAPSLLG------------GGSCSNMS------VTSS----RFSAGLG------------GSYGGGYTCSLGGGFGSSFGVS------------DALLGGSEKETMQNLNDRLATYLDRVRALEEANTDLEVKIREWYKKQ---GPG-PARDYSPYFKTIEDLRNKILAATIDNASIVLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIETLKEELAYLKKNHEEEMNALRGQVGGD-VNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNTEALQSSRTEITELRRSVQNLEIELQSQLSMKASLENSLAETEARYGAQLAQLQGLISSMEQQLCELRCDMERQNHEYQVLLDVKTRLEQEIATYRRLLEGEDAHLAT-----QYSSSLASQASREGTVTSRQ---VRTIVEEVQDGKVVSSREQVHRSTH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6IFX2-1", "uniprot_id": "K1C42_MOUSE", "id": "Q6IFX2-1", "name": "Keratin, type I cytoskeletal 42", "aln": "-----------MASTTSVRQFSTSGSVKGLC-----------APGM----GFSRMSSVRVGGACRAPSLLG------------GGSCGNMS------VTSS----RFSAGLG------------GGYGGGYTCSLGGGFGSSFGVS------------DALLGGSEKETMQNLNDRLATYLDRVRALEEANADLEVKIREWYKKQ---GPG-PARDYSPYFKTIEDLRNKILAATIDNASIVLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLRKNHEEEMNALRGQVGGD-VNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNTEALQSSRTEITELRRSVQNLEIELQSQLSMKASLENSLAETEARYGAQLAQLQGLISSVEQQLCELRCDMERQNHEYQVLLDVKTRLEQEIATYRRLLEGEDAHLAT-----QYSSSLASQPSREGMVTSRQ---VRTIVEEVQDGKVVSSREQVHRSTH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IFW5-1", "uniprot_id": "K1C12_RAT", "id": "Q6IFW5-1", "name": "Keratin, type I cytoskeletal 12", "aln": "-------MSLSVRTSALSRRSSSQNGVAGRP-WGASASSVACGYGG----TASGFGVG-CGGLLSAASMFG----------SSSGFSGGSTG-----CSPG-LGTAYGGPLGAGVG-------GMGIGGSSGGGSLCIFSGNDG---------------GLLSGSEKETMQNLNDRLASYLGKVRALEEANAELENKIREWYETRRTGDS-GSQSDYSKYYPLIEDLKNKIISASVSNAQLLLQIDNARLAAEDFRMKYENELALRQTVEADINGLRRVLDELTLARADLEAQTENLTEELAYMKKNHEEELQSFQAGGPGE-VNVEMDAAPGVDLT---------------------------KSGELRKEINSNTEQLQSSKSEVTDLKRMVQNLEIELQSQLAMKSSLEGSLAETEGGYCCQLSQMQQLIGSLEEQLQQLRADAERQNEDHQRLLGVKARLEMEIETYRRLLEG-DTQGDGFDESLSLTVSKPQAPSVDSSKDPNKTRKIKTVVQEIVNGEVVSSQVQELEEAM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64291-1", "uniprot_id": "K1C12_MOUSE", "id": "Q64291-1", "name": "Keratin, type I cytoskeletal 12", "aln": "-------MSLSVCTSALSRRSSSQNGAAGRP-WGASASSVAGGYGG----SASGFGVG-CGGLFSAASMFG----------SSSGFSGGSAG-----CLPG-LGSAYGGPLRGGAGGM---GIGMGIAGSSGGGSLCIFSGNDG---------------GLLSGSEKETMQNLNDRLASYLGKVRSLEEANAELENKIREWYETRRTRDA-GSQSDYSKYYPLIEDLKNKIVSARVSNAQLLLQIDNARLAAEDFRMKYENELALRQTVEADINGLRRVLDELTLTRADLEAQLETLTEELAYMKKNHEEELQSFQAGGPGE-VNVEMDAAPGVDLTKVLNEMRAQYEAMAEQNRKDAEAWFLEKSGELRKEISSNTEQLQSSKSEVTDLKRMVQNLEIELQSQLAMKSSLEGSLAETEGGYCCQLSQVQQLIGSLEEQLQQVRADAERQNADHQRLLGVKARLEMEIETYRRLLEG-DSQGDGFDESSSLSVSKPQTPSVDSSKDPNKTRKIKTVVQEIVNGEVVSSQVQELEEEM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99456-1", "uniprot_id": "K1C12_HUMAN", "id": "Q99456-1", "name": "Keratin, type I cytoskeletal 12", "aln": "MDLSNNTMSLSVRTPGLSRRLSSQS-VIGRP-RGMSASSVGSGYGG----SAFGFGAS-CGGGFSAASMFG----------SSSGFGGGSGS-----SMAGGLGAGYGRALGGGSFG----GLGMGFGGSPGGGSLGILSGNDG---------------GLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGE-VSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDG-EAQGDGLEESLFVTDSKSQAQSTDSSKDPTKTRKIKTVVQEMVNGEVVSSQVQEIEELM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NXG3-1", "uniprot_id": "A0A8M1NXG3_DANRE", "id": "A0A8M1NXG3-1", "name": "", "aln": "-------------MSQVTQSFSRKSVSSSRP------------FSS----QSVYAGAG---GSVRVSYAQS---------------------------------------------------------SRDGFDMSSALAEGDN-------------------GFEKTTMQNLNDRLASYLEKVRSLEKANAQLERQIREWYDKR-----TPVSRDYSHYYVTIEDLRKKISLASQDNARIILQIDNANLSAEDFRVKYENELALRLSVEADIAGLRKVLDDLTMTRSDLEMQIEGLKEELVYLKKNHAEELAALRAQMTSSSVNVEVDAAPQQDLARIMEEMRQQYEGITEKNKREMEAWYKGKFDELNKQVSTQQEDLSMSRNEINELGRTLQALEIELQSQLSLKSALEGTLGETESRYSIQLNQLQAVINSLEQELTQMRMDIERQASEYKLLLDIKTRLEMEIAEYRRLLDGEDIQRQT------------------------------VKVVEVVAPPQA-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q14525-1", "uniprot_id": "KT33B_HUMAN", "id": "Q14525-1", "name": "Keratin, type I cuticular Ha3-II", "aln": "-----------MPYNFCLPSLSCRTSCSSRP--------------------------------CVPPSCHG-------------------------YTLPG--------------------------ACNIPANVSNCNWFCEG----------------SFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQ----EPLLCPSYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRILDELTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDR-LNVEVDAAPAVDLNQVLNETRNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPS--------NPCATTNACEKP--------IGSCVTNPCGPRSRCGPCNTFGY--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . * ** *** ******:** :** ** * :** *:: : .*. *: ::::: ** : * ::****.*:*:*** *:: * ** **.*: .**::**:**: ::*** * * * *** :::** :*: : . :.**:*::* ** : **. :: :. : *: :* * .: ******:* :: .**..: * : : ** ::* :* ..* :* ::* : * * ::: *:.:::*** ** ** **:. : : ", "identical_positions": 101, "similar_positions": 88, "identity": "18.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2211", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P01024-1", "uniprot_id": "CO3_HUMAN", "id": "P01024-1", "name": "Complement C3", "aln": "--------------------MGPTSGPSLLLLLLTHLPLALGSPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDFPGKKLVLSSEKTVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQATFG-TQVVEKVVLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGSGEVVLSRKVLLDGVQNPRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQKPLS----ITVRTKKQELSEAEQATRTMQALPYSTVGNSNNYLHLSVLRTELRPGETLNVNFLLRMDR-AHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQP-VPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQPAARRRRSVQLTEKRMDKVGKYPKELRK-CCEDGMRENPMRFSCQRRTRFISLGEACKKVFLDCCN-----------------------------------------------------YITELRRQHARASHLGLARSNLDEDIIAEEN----------------IVSRSEFPESWLWNVEDLKEPPK-NGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQLAFRQPSSAFAAFVKRAPSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKD--ICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVAIAGYALAQMG-RLKGPLLNKFLTTAKDKNRWEDPGKQLYNVEATSYALLALLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLRSEETKENEGFTVTAEGKGQGTLSVVTMYHAK--AKDQLTCNKFDLKVTIKPAPETEKRPQDAKNTMILEICTRYRGDQDATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRDELCRCAEENCFIQKSDDKVTLEERLDKACEPGVDY----------------------VYKTRLVKVQLSNDFDEYIMAIEQTIKSGSDE-VQVGQQRTFISPIKCREALKLEEKKHYLMWGLSSDFWGEKPNLS----YIIGKDTWVEHWPEEDECQDEENQKQCQDLGAFTESMVVFGCPN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B5N7-1", "uniprot_id": "A0A8M3B5N7_DANRE", "id": "A0A8M3B5N7-1", "name": "", "aln": "MLLQLLLWATLLCQICDGKAFPQRHKRTVWRHMRQIEPVKDPSPSFSLLAPAKIRPGTKQNILVEGHNLAQVVEVTVVVYDYPNSQTALSRGSVFLNSDNNYS--VLQTLEINPNLLLPDGKKKYVKLVAQFSNIYRAEKVMAVSFRSGHIFIQTDKPIYNPGDKVRFRAFVSDLEFRSSERTISLEIQNPDGIAVHG-IGRVKAIDGVFSDIFSLSTVVKEGRWKVVAKFDQGKENVFSREFEVKKYVLPAFNVTLTPKTSHLSLDAEK-LEVEITARYLYGAQVKGVAYVLFGIEINGEKKRL-TSMKQIDDLNG-GSVSLTMEEIKR--AYPDINSLLGSTLYVKASVLTSSGSDLVEAEKSGIKIVKSPYMLTIKDTPKYYKPGLPLAMTVIVSNHDGSPTPNIPVKVTFLESPISVHSG--TINIHINMPKTHILYGNSQILKVETVDPSLKPEQQAIQEVYVKPYSTFSGHDNFLHVSVGASRVVVGGSVSVQMYIKSSLPNHRALVEHLTYIVLNKGKIIQAG-RVNVKGQDVTSVHLLITTEMLPAFRFVAYYVLP-WQHRAEVVADSVFVDVEDRCVGSLNVGPVDGEIVSSYSPGSSFKFQVKGDVGAKVSLVAVDNAIFLLSK-NRLTQKKVWEVVDQADMGCTAGGGKDNMGVFSDAGLMFHSSTGGSTDSKED--CSSKTKRRRRSAAKLQLRDQLEKAYSDELLQRCCVDGMKEIPMPYSCYRRSLYITEDWSCVLAFLRCCAEYRGEELGVITRPPPTTAPPTIAPPTTSPPTLFLVPHLEYHFPEQPVFFVRDRVLQSMPKLHAEANVVGVRQDSYREVVVEEEEEAASVFEEDDLSDLEDIYVRSKFFESWLWTDIRLPSTAKSDGLAVFPVDTVLPDSITQWGFLAVSASPEKGVCVAEPYNVRVWKPFFIDLRLPHSVSRNEQVEIKAVIHNYK-NSTLEVMVILEKTEDMCSVAYTG-QHRQQVTVAAGSSKLITYTIIPLKTGELPLQVTAVAASFMGQDAVKKNLRVVVEGIQTLKVRSFVLNPSEKGGSAGQQLIQVKKMQLDAVVPKSVPETFVNVRGDLLADSIDNSIKEDSLAALIRMPGGCVEQNLARITLPLIAAHYLDRSADWEIVGISRREEAIKYIQRGYENQLNYKKSDDSYPPYANEGTSTWITAYVVKVFSMAHSFINVNEKHLCGPLLYLLKNKQGYDGTFQEDNPVYDTSMTGAMRGS-EYKASLTAFVLIALAEAQDKVTCQDQEVNIRDKSRQAAGYLTEHFSRLTRPYTAAIACYALAVSNNACVKSMLLKFAS--PDHSHWPDSNNYFFTLEATGYALLALIKSGHMEEAEAPFRWLNEHRGIGGGYGSTQSTMVVLQALSEYLVKRPPPSDLNLLVQLSVPGRSD-VRWTFNPNLAYVARSSRVPLDQEFSVAASGNGKGVLEVVTVYHQLPDVYENSTCNGFQLDVSIAET--NEKTSSDVEKSFRLNVNVRALEERQVRMVILDIGLPTGFEPENSDLELLTNSVDRYINNFQVVDNLSDRGSLIIHLFKVSNKEAEMISFRLNQKFKVGLLQPSTVKVYQYYNKDKSCSRFYSPPEDKQQLDQICEGDVCRCSQGDCCVMKEDFAFFGKEQRNAAVCNGLHHGEYFFRVNYCCLLFLSMNNFSSAYRVKLISISQS-HYYQYEMEIVQVIKEGTEEGLNEKERRMFLSHASCRTRLNLKEGQEYLVIGPITDVWNAGSTVSNKYVYTLGKETWVERWPDESECG-STLQKKCDELKSFAKKLIEDGCQA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: : *: ** :*:::* :* :::.:::*.*: * ***.*:*:*..: .** ...*.. .*: * *: * :: .*::*:*.: * *. .***: **::**::******.**.**..* :* *. : :: . **: ::*:**:**.*: : **:. :.:. :*: *:**: * :::. ::*** *****:****:*:* : *. .. : ** *** ****:*** :*:*.*:*:***: . :: * *:*:* :* *.* *: : : * :.*:*.:***.*:*: ****:*:**:*** **.*** : :..****:***:*: : *:*:* ****: .:** * :: *: .* . :: ** :: . :.*.* . .*. :** : : . ****... :*:**:** :.: * ::.*:: :: . *.* :.: **:::***::::** :*. ***:. : * ***:::*:**:****.* . : *******:***:* ***** * . :.* .. **..:.::::** **:* *****:.:*:*.* *:***.*:*:**::**:***.*.*** ******** * **:* .* .: : *.. : *****. : * : *..** : ** ***:* ** :** **: :*: . :* .** ** : .: : **.*. :*: :.. * :: **: * **:* *****. * ...* :*::. :: .* **** * :**** * :**:***:*::* * : ********:** *******:**::**: *. *:* * * :. :**:* * :*:* **:.. ** :.*.*:***** ::*.*.. .: .*.*:*.*:** ***: *. :. .*: * * * :: :*. **.: .** : ::* :*: ::::. : * ** *.** ***: :* .:**.****.: :** .*:.:*: *:: *::** :** :::...::..:.:...***:*********:* .:* ::.: ***.: :*: :** **.**** ** . .* *.:*.. * . :*******:* **:* *::* .: .. :*..:* :: .* *.**.*** **** . .:* ** : *:.:* *..: ::.:***.******:: .:: . . .*****:* ********:*::*:***::* . * .:*** *.*.:*.**. : :: : * : **... :: *:*:*.*:*:*.*.***:** . :: *** *:*.*:* : .** ..*.:::: *:: .* :::. * ****.: *** *:..**: *:*.*****.:::: . :***.:***:* ***:.* : ::*:::* *:* *:**.:**** *** ::**:*** * ::. :*:::*..::***:: :* : *.* . :*: : * *:.: .*:.:*:.:. * .: :* * * *.**.*::* :: ::* *:* .** *:*:* :.**: * :*.*. ..:* * :**:****:**:*.** . **:*::* :*::.:: ** ", "identical_positions": 644, "similar_positions": 590, "identity": "35.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2214", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q53ET0-1", "uniprot_id": "CRTC2_HUMAN", "id": "Q53ET0-1", "name": "CREB-regulated transcription coactivator 2", "aln": "MATSGA--------NGPGS-ATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLAYTRSSHYGGSLPNVNQIGSGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRRYTRHIDSSPYSPAYLSPPPESSWRRTMAWGNFPAEKGQLFRLPSALNRTSSDSALHTSVMNPSPQDTYPGPTPPSILPSRRGG-ILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSSRPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTPLDPEETAYPSLSGGNSTS-NLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVLGAPSYPASTPGASP------HHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLSTDQRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSHYGTPYPPGPSGHGQQSYHRPMSDFNLGNLEQFSMESPSASLVLDPPGFSEGPG-----------FLGGEGPMGGPQDPHTFNHQNLTHCSRHGSGPN---IILTGDSSPG---FSKEIAAALAGVPGFEVSAAGLELGLGLED---------------------ELRMEPLG-----------------------------------LEGLNMLSDPCALLPDPAVEESFRSDRLQ------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3U182-1", "uniprot_id": "CRTC2_MOUSE", "id": "Q3U182-1", "name": "CREB-regulated transcription coactivator 2", "aln": "MATSGA--------NGPGS-ATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLAYTRSSHYGGSLPNVNQIGCGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDARRMVSPLRRYPRHIDSSPYSPAYLSPPPESGWRRMMPWGNLPAEKGQLFRLPSALNRTSSDSALHTSVMNPNPQDTYPGPTPPSVLPSRRGGGFLDGEMDAKVPAIEENVVDDKHLLKPWDAKKLSSSSSRPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTPLDPEETVYPSLSGGNSTT-NLTHTMTHLGISGGLGLGPSYDVPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLAHHALPTTSLGHPSLSAPALSSSSSSSSTSSPVLSAPPYPASTPGASP------RHRRVPLSPLSLPAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLPTDQRLPPYPYSPPSLVIPTHPPTPKSLQQ--LPSQACLVQPSGGQPPGRQPHYGALYPPGSSGHGQQPYHRPINDFSLGNLEQFNMESPSTSLVLDPPAFSEGPG-----------FLGSEGSMSGPQDPHVLNHQNLTHCSRHGSGPN---IILTGDSSPG---FSKEIAAALAGVPGFEVSASGLELGLGLED---------------------ELRMEPLG-----------------------------------LEGLTMLSDPCALLPDPAVEDSFRSDRLQ------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FDT8-1", "uniprot_id": "E7FDT8_DANRE", "id": "E7FDT8-1", "name": "", "aln": "MHFSGAGLGEIGHGQGPGPGPTPGSCNPRKFSEKIALHNQRQAEETAAFREVMMDINSIRVEAERVRQTRDPVPYYGGSLPNVNQMSRCSVETQYPSCLTQQLLEADEEYRDVQPSPLS--------RPYRRHFDSAPYLSSHLSPPRAPAWRRNWSSCSATEKSQMVRLPLTALNRTNSDSALHTSVRN-TQLHGHLKSTQTLNTQTRHCG------FALPAPLIEENIQEETQSPKLKKLSPMASSG-----CETP-VVHFPSPDQQVSSLPVPSALSTSGSLPDLSSLHLPSPLPGGLESEPQSGTNLLNSTSTHPDIMADFSLPGLSSPLQASLSNPLLQSSS-LSNPSIQSCLSSLSLPSSLSSVSSRLSLSNSS---LQSSLSNQSLR-SSLSSSSLSNQSVQSSASRCSISSGIGGSGSCSSSSVSGSPRVAGGTSRKRAQLSPLIVPSG----GESRWQHPKQFSPTASPTLPSIAQGALLNSCKVHKETKPPAYPCSHHIRPAPPLSHQPLRQYFHPEPQYQSIPELEQWIHNEHQQTHNQRQKHSPVHKHPQTHAKFEPHLQYPPQQAFTQHAPLYPQIQHHHHHQEQQNQWHQQNQYQNQQLHQNTAIQCPDQEQNWSHFTGVHELQHTQVKRRYCMQTQDDTKPPSELTNPETPAAVSHCKETEQNPGSQDKGFELNKESYVGLHLTPSQAKALSQQLGALQKEPLGGSRGSELHCEAAESREQQNQSCSAGETHNAFNINLSDPSSWLDQDISGLPDSVLEFDLETFGLDSNLGWP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *** :***. .*..:.***********::**********.******.* *::*:::* : .:**********:. .* * * . : .: ..: *: . * * **:**:** .::**** ..*** . . . :. : :*****.********* * . . : .* . :*: * : .* ****: ::.: * . . ::**. **.* : ****** .. :*.*:.*.******:.**:*.*** *:.* ..* ...** :: :: *:* : . . * **:**:**.**. .* :**** ..:*. *:* ***:.: * :**. .*** ::.**:* .* ** : .: . .:*: ..** ::*. **** : :* .*: * ******* ****.**:**. *::.*: .: : *.** * *. . * *. . : . :* :. .. : *.: : .:. : *. .:* . : . ..* . * : .: *:: : .* . .* :* . . : .*:.* . * .**:: * .... : *: *:. *: **** : . *.: : ***..:* .:.: *: ", "identical_positions": 221, "similar_positions": 212, "identity": "28.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2219", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q92845-1", "uniprot_id": "KIFA3_HUMAN", "id": "Q92845-1", "name": "Kinesin-associated protein 3", "aln": "MQGEDARYLKRKVKGGNIDVHPSEKALIVHYEVEATILGEMGDPMLGERKECQKIIRLKSLNANTDITSLARKVVEECKLIHPSKLNEVEQLLYYLQNRRDSLSGKEKKEK-SSKPKDPPPFEGMEIDEVANINDMDEYIELLYEDIPDKVRGSALILQLARNPDNLEELLLNETALGALARVLREDWKQSVELATNIIYIFFCFSSFSQFHGLITHYKIGALCMNIIDHELKRHELWQEELSKKKKAVDEDPENQTLRKDYEKTFKKYQGLVVKQEQLLRVALYLLLNLAEDTRTELKMRNKNIVHMLVKALDRDNFELLILVVSFLKKLSIFMENKNDMVEMDIVEKLVKMIPCEHEDLLNITLRLLLNLSFDTGLRNKMVQVGLLPKLTALLGNDNYKQIAMCVLYHISMDDRFKSMFAYTDCIPQLMKMLFECSDERIDLELISFCINLAANKRNVQLICEGNGLKMLMKRALKFKDPLLMKMIRNISQHDGPTKNLFIDYVGDLAAQISNDEEEEFVIECLGTLANLTIPDLDWELVLKEYKLVPYLKDKLKPGAAEDDLVLEVVIMIGTVSMDDSCAALLAKSGIIPALIELLNAQQEDDEFVCQIIYVFYQMVFHQATRDVIIKETQAPAYLIDLMHDKNNEIRKVCDNTLDIIAEYDEEWAKKIQSEKFRWHNSQWLEMVESRQMDESEQYLYGDDRIEPYIHEGDILERPDLFYNSDGLIASEGAISPDFFNDYHLQNGDVVGQHSFPGSLGMDGFGQPVGILGRPATAYGFRPDEPYYYGYGS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70188-1", "uniprot_id": "KIFA3_MOUSE", "id": "P70188-1", "name": "Kinesin-associated protein 3", "aln": "MQGEDARYLKRKVKGGNIDVHPSEKALIVQYEVEATILGEMGDPMLGERKECQKIIRLKSLNANTDITSLARKVVEECKLIHPSKLSEVEQLLYYLQNRRDSLPGKEKKEK-SSKPKDPPPFEGMEIDEVANINDMDEYIELLYEDIPDKVRGSALILQLARNPDNLEELLLNETALGALARVLREDWKQSVELATNIIYIFFCFSSFSHFHGLITHYKIGALCMNIIDHELKRHELWQEELSKKKKAVDEDLENQTLRKDYDKTFKKYQGLVVKQEQLLRVALYLLLNLAEDTRTELKMRNKNIVHMLVKALDRDNFELLILVVSFLKKLSIFMENKNDMVEMDIVEKLVKMIPCEHEDLLNITLRLLLNLSFDTGLRNKMVQVGLLPKLTALLGNENYKQIAMCVLYHISMDDRFKSMFAYTDCIPQLMKMLFECSDERIDLELISFCINLAANKRNVQLICEGNGLKMLMKRALKLKDPLLMKMIRNISQHDGPTKNLFIDYVGDLAAQISSDEEEEFVIECLGTLANLTIPDLDWELVLKEYKLVPFLKDKLKPGAAEDDLVLEVVIMIGTVSMDDSCAALLAKSGIIPALIELLNAQQEDDEFVCQIIYVFYQMVFHQATRDVIIKETQAPAYLIDLMHDKNNEIRKVCDNTLDIIAEYDEEWAKKIQSEKFRWHNSQWLEMVESRQLDESEQYLYGDDRIEPYIHEGDILERPDLFYNSDGLITSEGAISPDFFNDFHLQNGDVVGQHAFPGSLGMDGFGQPLGILGRPATAYGFRPDEPYYYSFGSR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q1LWL1-1", "uniprot_id": "Q1LWL1_DANRE", "id": "Q1LWL1-1", "name": "", "aln": "MQPDETQYLQRRCRIGDIDVHPTEKALVVYYEVEASILGETGNARHEEKKDCQKIIRLRSLNASTDISALAKKVVEECKLIHPSKLKEVEHLLLYLQNRKKPSTKLEKKEKKAQKPRELLLFEGMEIDEEANINKIEEYIELLYESIPEKIRGSTLILHLARNPDNLEELLHNETALGALARVLREDWKHSVELATTIIYVFFCFSSFSQFHGLITHYKIGALCMNVIEHELKKYDLWQDELEKKSKACDEDPDNHSLRKEHEKTFKKYQSLLVKQEQLLRVAFYLLLNLSEDTRTELKMRNKNIVHLLVKSLDRENEELLVLVVSFLKKLSIFLENKNDMAEMDVVEKLAHLVPCEHEDLMNVTLRLLHNLSFDTGLRTKMVHVGLLPKLTALLGDDTHKLVVMRILYHISVDDKSKSMFAYTDCIPQLMQMLFEHGEERIDTELISFCINLAANKTNSQIMCEGNGLKMLMRRALKLKDPLLMKMIRNISQHDGPLKQLFIDYVGDLAAQIKKEGDEEFVIECLGTMANLTIPDLDWELLLKEYNLVPFLKDHLKPGSAEDDMILEVVIMIGTVSMDDSCAVMLAKSGIIPALIELLNAQQEDDEFVCQIIYVFYQMVFHQATRDVIIKDTQAPAYLIDLMHDKNVEIRQVCDNTLDIIAEYDEEWGKKIQSEKFRWHNSQWLEMVESRQMEDGEPYMYGDD--------PEALEQPDLFYSTDGMMNPEPGISPDFYSQFHPQNGD------FNACNGSD---------GRPATAYGFRPDEPFFHGYGSTR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ::::**:*: : *:*****:****:* *****:**** *:. *:*:*******:****.***::**:**************.***:** *****:.. . ***** :.**:: ******** ****.::********.**:*:***:***:************ *****************:******.***:********:****************:*:****:::***:**.**.** *** :*::***:::*******.*:**********:******:****************:***:***:* ***:************:******.***:****.:::*******:*:***** *********.***:************::.:* :.* :*****:**: **************:**** .:**** ************* * *::**********:****:****************** *:*************..: :**********:************:****:***:***:****:****::*****************.:**********************************************:*************** ***:****************.***********************:::.* *:**** : **:*****.:**:: .* .*****:.::* **** * .. * * **************:::.:** ", "identical_positions": 596, "similar_positions": 133, "identity": "74.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-223", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P38656-1", "uniprot_id": "LA_RAT", "id": "P38656-1", "name": "Lupus La protein homolog", "aln": "---------------------------------------------------------------------------------MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLD-EGWVPLETMIKFNRLNRLTTDFNVIVQALSKSKANLMEVSADKTKIRRSPSRPLPEVTDEYKNDVKNRSVYIKGFPTDATLD--------DIKEWLDDKGQILNIQMRRTLHK-----TFKGSIFAVFDSIQSAKKFVDTPGQK-YKDTNLLILFKEDYFAKKNEERKQSKVEAKLKAKQEHEGRHKPGS-TETRALEGKMGCLLKFSGDLDDQTCREDFHFLFSNHG--EIKWIDFVRGAKEGIILFKEKAKDALEKARSANNG-NLLLRNKKVTWKVLEGHAEKDAMKKITDDQQESLNKWKSKGGHAARRFKGSHVFTAARRFKGRGKGNRPAYAGAPKGRGQFQGRRTRFDDDDHR--------RGPVKRGIDGRDREEPASKHKKRENGARDK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32067-1", "uniprot_id": "LA_MOUSE", "id": "P32067-1", "name": "Lupus La protein homolog", "aln": "---------------------------------------------------------------------------------MAENGDNEKMTALEAKICHQIEYYFGDFNLPRDKFLKEQIKLD-EGWVPLETMIKFNRLNRLTTDFNVIVQALSKSKAKLMEVSADKTKIRRSPSRPLPEVTDEYKNDVKNRSVYIKGFPTDATLD--------DIKEWLDDKGQILNIQMRRTLHK-----TFKGSIFAVFDSIQSAKKFVEIPGQK-YKDTNLLILFKEDYFAKKNEERKQSKVEAKLKAKQEHEGRHKPGS-TETRALEGKMGCLLKFSGDLDDQTCREDLHFLFSNHG--EIKWVDFARGAKEGIILFKEKAKEALEKARNANNG-NLLLRNKKVTWKVLEGHAEKEALKKITDDQQESLNKWKSKGGHAGGRFKGSHVFTAARRFKGKGKGNRPGYAGAPKGRGQFHGRRTRFDDDDRR--------RGPMKRGRDGRDREEPASKHKKRENGARDK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05455-1", "uniprot_id": "LA_HUMAN", "id": "P05455-1", "name": "Lupus La protein", "aln": "---------------------------------------------------------------------------------MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLD-EGWVPLEIMIKFNRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPTDATLD--------DIKEWLEDKGQVLNIQMRRTLHK-----AFKGSIFVVFDSIESAKKFVETPGQK-YKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHG--EIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNG-NLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKG----------------RRFKGKGKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGAGDQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JQB7-1", "uniprot_id": "A0AC58JQB7_DANRE", "id": "A0AC58JQB7-1", "name": "", "aln": "MQLHEARSPKPELVPVNVYDRSCVLCTICTQAMHMFSVLLKRNKITTELWPVSCCLTGGVIGVDGYTVIQRSTNEVMFVVILAKMADNQEMSPLEKKVAEQIEYYFGDHNLPRDKFLKEQLQLD-DGWVPLETMLKFNRLKSLTSEESVIVESLLKSKTGLLEISEDKTKIRRDPNKPLPENNEEYRDALKHKSIYMKGFPLETTLD--------DVKEWLADKGTFENIYLRKGPQK-----TFKGSIFAVLETEEAAKAFVERDDIKNFKGNEMIVMMKDAYFTKKIAERKQNRVESKAKAKCDKEEKQKQAEEEEMKSLNEQRGCLLKFSGELG-QTSREDFHSVFSDHA--QIKWIDFTRGAKEGTILFHSNAKEALQKVREALNGEDPKVKEQAVQWEILEGDVEMETLKKIIEDQQESINKRKGGRG----------------GFRGRGRGRGGRRDRGGREHTQFKGKKTKFDSDEEGDEESASTKKRPLESNRQ--DNGEPVSKQAKSENGS---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40796-1", "uniprot_id": "LA_DROME", "id": "P40796-1", "name": "La protein homolog", "aln": "--------------------------------------------MAEVAETPSVEAQEEVAQPAEAQVLEAKNGDAKKDPAPAAEEAAGGFTKQERAIIRQVEYYFGDANLNRDKFLREQIGKNEDGWVPLSVLVTFKRLASLSTDLSEIVAALNKSEEGLVEISEDKLSLRRHPERPIPEHNEERRKEIQERTAYAKGFPLDSQIS--------ELLDFAANYDKVVNLTMRKHYDKPTKSYKFKGSIFLTFETKDQAKAFLEQEKIV-YKERELLRKWQVDYLKEKQEEYAQKNEKRKNKKEAKPEP-----------AFELPKNAIVVFEGAPE-TSSREEIREAFEKIKDFEVAYIEFAKGETKGSVRLTEADAAEKYIAKVEEGK-LKFKDEVSLSLRKATEEEEKEFIDKAIEFMKKRRDFTRNKGK----------------RFNRKRHGGNDHKHGG--------GKKARGD-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33399-1", "uniprot_id": "LHP1_YEAST", "id": "P33399-1", "name": "La protein homolog", "aln": "-----------------------------------------------------------------MSEKPQQEEQEKPQSRRNSFAVIEFTPEVLDRCLKQVEFYFSEFNFPYDRFLRTTAEKN-DGWVPISTIATFNRMKKYRP-VDKVIEALRSSE--ILEVSADGENVKRRVPLDLTAARN-ARIEQNQRTLAVMNFPHEDVEASQIPELQENLEAFFKKLGEINQVRLRRDHRNK----KFNGTVLVEFKTIPECEAFLKSYSND-DESNEILSYEGKKLSVLTKKQFDLQREASKSKN----------------------------FSGRSR-----------------------SFNGHKKKNLPKFPKNKKKNGK-------------------------EESKEDSSAIADDDEEHKE-------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .*:*:**.: *: *:**: : :****:. : .*:*: . . :: :* .*: ::*:* * .::* :. : : :.:: .** : :: : . . . :: :*: : *:*::: :.: .: *:. : ::: . : .. * : *.* .* .:. : . . . : . : :: : ", "identical_positions": 30, "similar_positions": 86, "identity": "5.74%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-224", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35226-1", "uniprot_id": "BMI1_HUMAN", "id": "P35226-1", "name": "Polycomb complex protein BMI-1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHRTTR---IKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADEDKRIITDDEIISLSIEFFDQNRLDRKVNKDKEKSKEEVNDKRYLRCPAAMTVMHLRKFLRSKMDIPNT-FQIDVMYEEE--PLKDYYTLMDIAYIYTWRRNGPLPLKYRVRPTCKRMKISHQR----------DGLTNAGELESDSGSDKAN--------------------------------------------------------SPAGGIPSTSSCLPSPSTPVQSP-----------------------HPQFPHISSTMN-------------GTSNSPSGNHQSSFANRPRKS-----------------SVNGSSATSSG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25916-1", "uniprot_id": "BMI1_MOUSE", "id": "P25916-1", "name": "Polycomb complex protein BMI-1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHRTTR---IKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADEEKRIITDDEIISLSIEFFDQSRLDRKVNK--EKPKEEVNDKRYLRCPAAMTVMHLRKFLRSKMDIPNT-FQIDVMYEEE--PLKDYYTLMDIAYIYTWRRNGPLPLKYRVRPTCKRMKMSHQR----------DGLTNAGELESDSGSDKAN--------------------------------------------------------SPAGGVPSTSSCLPSPSTPVQSP-----------------------HPQFPHISSTMN-------------GTSNSPSANHQSSFASRPRKS-----------------SLNGSSATSSG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABZ3NNP3-1", "uniprot_id": "A0ABZ3NNP3_RAT", "id": "A0ABZ3NNP3-1", "name": "Polycomb complex protein BMI-1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELRVFYQAEMHRTTR---IKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADEDRRVIADDEIISLSIEFFHPSRSDRKVTK--EKPKEEVNDKRYLRCPAALTVMHLRKFLRSKMDIPNT-FQIDVMYEEE--PLKDYYTLMDIAYIYTWRRNGPLPLKYRVRPTCKRMKMSQQR----------DGLTAAGELESDSGSDKAN--------------------------------------------------------SPAGGAPSTSSCLPSPSTPVQSP-----------------------HPQFPHISSTMN-------------GTSNSPSGNHQSSFASRPRKS-----------------SVNGSSATSSG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JIR0-1", "uniprot_id": "BMI1A_DANRE", "id": "Q8JIR0-1", "name": "Polycomb complex protein BMI-1-A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHRTTR---IKITELNPHLMCVLCGGYFIDATTIIECLHSFCKMCIVRYLETSKYCPICDVQVHKTKPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAEHPSVDAANGSNEDRGEVADEDKRIITDDEIISLSIEFFDHRAQQQGCTE--ERQKEEVNNKRYLQCPAAMTVMHLRKFLRSKMDIPPT-YQIEVMYEDE--PLKDYYTLMDIAYIYTWRRNGPLPLKYRVRPSCKKMKITHPQ----------EGLNNANRSESDSASDKAC--------------------------------------------------------SPAG-VPSTSSPLPSPSTLVQPS-----------------------QPHFTHISSPIN-------------GTTMT-SPNRQFNFS-KVRKS-----------------ALNGS-STSSG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35820-1", "uniprot_id": "PSC_DROME", "id": "P35820-1", "name": "Polycomb group protein Psc", "aln": "MMTPESKAIQPAAATTKQTAEATATTTMAHTQQKSQLSTLAKTTTTTATNKAAKSVVSNANSSGNNSSKKLALSQSQKTTTTTTPPTTTTTTTAAAAAEATTNADKMQKQQQLKQQLFAACSIKVKSENTLATTANAALAAATTTTTTATPALATGKAAKTILENGIKKESTPPAVESVEASSSSSSSSSSSSSSSSSWPTTRRATSEDASSNGGASADEEKSEEDPTAAVAASSTATTTSDLATTSRPRPVLLTAVNPHIICHLCQGYLINATTIVECLHSFCHSCLINHLRKERFCPRCEMVINNAKP--NIKSDTTLQAIVYKLVPGLYERELMRKRAFYKDRP-EEAALATPEQRG--DDTEHLIFSPSDDMSLSLEYAELG--ELKTDS--EPELVDTLRPRYLQCPAMCRVSHLKKFVYDKFEIDAQRFSIDIMYKVKTIVLLDYYTLMDIAYIYTWKRDAPMRFYYRVYESPQPLVKPAPRRVLPLKLEKQERENQEQQLAVEVASSKVEPVSLPEDQKAEASIKVEEQESTREIVKEVIKDVAATPPTETLKLVINRNMLDKREKSHSPQMSSKSSSKSSPCTPVSSPSEPNIKLKIDLSKQNSVTIIDMSDPERREIVKPLKPEKESRSKKKDKDGSPKSSSSSSSSSSGERKRKSPSPLTVPPLTIRTERIMSPSGVSTLSPRVTSGAFSEDPKSEFLKSFALKPIKVKVESPERTLNNRAITPPSPSVQQSASPKSKGNNLDDSILMKPPSCMPPKSIASSKRKSKEPVKAVSKKQKLSPPLPTVDFKIRLPVTNGNSSGTASPKIEKPLMPPPAKPPMLAPRKLQPSAQFAPPPSPIHHHAGVQMSAPGNRTPIAKRYQPILPKASRPNPFANIPNDVNRLLKDAGTEIKSIGGGSVENNSNAAQKPHLYGPKGESKMGPPALPATTPSQGNKNVGKQAGNLPMSAPPNKGNSSNNYLNLALFNSSKCKGKEAPPGCRTPMYTPNSPIYSPSSPQYVPSYNIPTMPTYKYTPKPTPNSGSGNGGSGSYLQNMLGGGNGGSLGGLFPSPPTKSDQNTNPAQGGGGSSSATQSGGNNGIVNNNIYMPNEDAPEKQQVKVKSLLNSCNINIPSSLSITISRDNGDSSSPNNGQHPKHKSPVNNYIEIVKLPDQPQDQVQAAKEAQKRQSPPAAVPGHLAAKLPPPPPSKAIPSPQHLVSRMTPPQLPKVATPPPPSSPRVITPPKTSPPANAAKVTPLKPVLTPTQVDKKTPSPEKRTAAQMGSHSPTASENKSPKGGPAGVANSTGGAQNGDPAAKKFRPILPRQNGMPELAPKLPTLAPFVGFNPLQNPAAGKKVPPSKKSPNAGAAAHQSGQQKLVNGGQSQPAQQKTSPPAQKNQQQVKKVSKNPTPPPPSLPAVGKMMPHPVMHSQNAPLSIASSASAAAVASGQLDLSNFLKENLRRVHAAQAAQAAQVAAAANQSNMMYNLAQMGHMTPAMYNYQQAYFREQLSRMQRVGNEVFNDYLQKLKTAAATGGGGPVEGELKPMLPTVTLPSPGATPPAASPKTSPLPAGKLTAAATAPQTKGNSSSGAANARQQTAATGNNGATVPAASLPPATKSK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:* : :* :***::* ** **:*:****:*******: *::.:*...::** *:: :::::* **:**.*** *********::.*: *:* ** :* :** .: *:** * :: ::: .: :***:*: . : . * :. ***:*** * **:**: .*::* :.*::**: : * **************:*:.*: : *** : : : . : : . . : .*.*. * : .*.** .**.* *... .*. .* ..:: *:. : * . . . . : *** : .* : *. ", "identical_positions": 117, "similar_positions": 110, "identity": "7.27%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2248", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZYN4-1", "uniprot_id": "A0A8I5ZYN4_RAT", "id": "A0A8I5ZYN4-1", "name": "", "aln": "---------------MSGSGAAPGPGSGSSP------------------------------------AACRFAHYFVLCGIDADSGLEPDELA--------------------GENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQADNKDPQFHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEQ-----------YSSVYASSSCSMDS-LASSIDEGDATSLLKLQR-YNSYDINRDTLYVSKSICLITPLPFMQACRKFLLQLHKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYG-VYEP------VICQRPGPN-ELPLSDYPLREACELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKVDFIQELSEVLLQFGIPPEG-------------------------------------SLHCSESATKLKNMVLKDLANDKK--NGNVPTNNVSVYELLKGS---ETIARLQALAKRTG--------VTVGKIDFPAS-----------------LSEKEKDLKLQCEEADLRDSQLNVQLREVFANRFTQMFADYEAFVIQTAQDMESWLTSREQMQNFDKASFLSDQPEPYLPFLSRFIETQMFATFIDNKIMSQWEEK-DPLLRVFDSRIEKMRLYNVRAPTLRTSIYQKCSSLKEAAQSIEQRLMKMDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPANNNRWVSRSTTAQRRKERLRQNAEHIGLDSDLREPSGELLVCQNSMAFWEWDQGPTPPARLPKKSFSECCLKYMQEARSLGKNLRQPKLSDLSPAVIAQTNWKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLLVKQGKSALWSHLIQFQDREEKQ----------------------------------------------EHLTDSPVALGPER-RKSDSGVMLPTLR---VSLIQDMRHVQNMTEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLTKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIMIPYRSVIIPIKKLSNAIITSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGVDDGSLERILIGELMTS-ASDEDLGKQC--RTPPQQKSPTTTRRLSITSLTGKPAKPNAGQIQEGIGEAVNNIVKHFHKPEKER--GSLTVLLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFVEKAVAYFESTDQILDNEDDM----------------LIQKPSCKTFCHYVNAVNTAP-RNIGKDGKFQILVCLGTRDHLLPQWIPLLAECPAITRMYEENALLRDHMTVNSLIRILQTIQDFTIVLEGSLIKGVDV----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2RSQ0-1", "uniprot_id": "DEN5B_MOUSE", "id": "A2RSQ0-1", "name": "DENN domain-containing protein 5B", "aln": "---------------MSGSSAAPGPGSGSSP------------------------------------AACRFAHYFVLCGIDADSGLEPDELA--------------------GENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQADNKEPQFHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEQ-----------YSSVYASSSCSMDS-LASSIDEGDATSLLKLQR-YNSYDINRDTLYVSKSICLITPLPFMQACKKFLFQLHKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYG-VYEP------VICQRPGPN-ELPLSDYPLREACELLGLENLVQVFTCVLLEMQTLLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKVDFIQELSEVLLQFGIPPEG-------------------------------------SLHSSESATKLKNMVLKDLANDKK--NGNVPNNSVSVYELLKGS---ETIARLQALAKRTG--------VTMEKIDLPAS-----------------LSEKEKDLKLQCEEADLRDSQLNVQLREVFANRFTQMFADYEAFVIQTAQDMESWLTNREQMQNFDKASFLSDQPEPYLPFLSRFIETQMFATFIDNKIMSQWEEK-DPLLRVFDSRIEKIRLYNVRAPTLRTSIYQKCSSLKEAAQSIEQRLMKMDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPANNNRWVSRSATAQRRKERLRQSSEHIGLDSDLRE-------------------------------------KYMQEARSLGKNLRQPKLSDLSPAVIAQTNWKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLLVKQGKSALWSHLLQFQDREEKQ----------------------------------------------EHLTDSPVALGPER-RKSDSGVMLPTLR---VSLIQDMRHIQNMTEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLTKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIMIPYRSVIIPIKKLSNAIITSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGVDDGSLERILIGELMTS-ASDEDLGKQC--RTPPQQKSPTTTRRLSITSLTGKPAKPNAGQIQEGIGEAVNNIVKHFHKPEKER--GSLTVLLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFVEKAVAYFETTDQILDNEGDV----------------LIQKPSSKTFCHYVNAINTAP-RNIGKDGKFQILVCLGTRDHLLPQWIPLLAECPAITRMYEENALLRDHMTVNSLIRILQTIQDFTIVLEGSLIKGVDV----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZUT9-1", "uniprot_id": "DEN5B_HUMAN", "id": "Q6ZUT9-1", "name": "DENN domain-containing protein 5B", "aln": "---------------MSGSCAAPGPGSGSSP------------------------------------AACRFAHYFVLCGIDADSGLEPDELA--------------------GENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQTDNKDPQFHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEH-----------YSSVYASSSCSMDS-LASSLDEGDTTSLLKLQR-YNSYDISRDTLYVSKSICLITPLPFMQACKKFLIQLYKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYG-VYEP------VICQRPGPS-ELPLSDYPLREAFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKVDFIQELSEVLVQFGIPPEG-------------------------------------SLHCSESTSKLKNMVLKDLVNDKK--NGNVCTNNISMYELLKGN---ETIARLQALAKRTG--------VAVEKMDLSAS-----------------LGEKDKDLKLHCEEAELRDYQLNVQLREVFANRFTQMFADYEAFVIQTAQDMESWLTNREQMQNFDKASFLSDQPEPYLPFLSRFIETQMFATFIDNKIMSQWEEK-DPLLRVFDTRIDKIRLYNVRAPTLRTSIYQKCSTLKEAAQSIEQRLMKMDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPTSNNRWVSRSATAQRRKERLRQHSEHVGLDNDLRE-------------------------------------KYMQEARSLGKNLRQPKLSDLSPAVIAQTNCKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLIQFQDREEKQ----------------------------------------------EHLAESPVALGPER-RKSDSGVMLPTLR---VSLIQDMRHIQNMSEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLTKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIMIPYRSVIIPIKKLSNAIITSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGIDDGSLERILIGELMTS-ASDEDLVKQC--RTPPQQKSPTTARRLSITSLTGKNNKPNAGQIQEGIGEAVNNIVKHFHKPEKER--GSLTVLLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFIEKVVAYFETTDQILDNEDDV----------------LIQKSSCKTFCHYVNAINTAP-RNIGKDGKFQILVCLGTRDRLLPQWIPLLAECPAITRMYEESALLRDRMTVNSLIRILQTIQDFTIVLEGSLIKGVDV----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NXD8-1", "uniprot_id": "DEN5B_DANRE", "id": "Q6NXD8-1", "name": "DENN domain-containing protein 5B", "aln": "---------------MSAT------MSGSGS------------------------------------APCRFAHYFIVCGLDDETGLEPDALAALYQWLEADRQGKDPEATAAGENFDQSPLKRTFKSKVLAHYPENIECNPFDQDAVNMLCMPKGLSFRTQRDSLAPHFHSFLITREDGSRTYGFVHTFYEEVTSPQICSAMQTLHQMHQAEHNTSAQNCTSSSSSSSSSSSSSSMDS-LSSSLDDVDSPSAHGGRRTCEGYDSIRDTLYVSKAMCLIAPMPFMHACKRFLAQMHRAVSCSPPPPLPLESYIYNVLYEVPLPASGRSLKFHG-VYEP------ILCQRPGVG-ELPLADFPLADAFRLLGVENLVQLFTCVLLEMQILLYSQDYQRLMVVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHCIELPEDFPQFPNRSEFIQELSEVLLSFGQSPEGGSSSPEP---------------------------AVMSLQTSVLEKELKSTSLRELVDDKT--NGNLGGEALDVLELLQGN---PTLERLQALAKRTG--------VKVARLEALAAGQ---------------KGDEGVGGRSPVEEEELRNAKLNVQLREVFAARFATMFADYESFVIQNSPDLESWLTNREQMHNFDKASFLSDQPEPYLPFLSHFIETQMFATFIDNKIMSQWEEK-EPLLRVFDGRIEKARLYNVRAPSLRSSVYQKCTFLKESAQAIEQRLRKIDHTAIHPHLLDMKIGQGKYQQGFFPKLQADVLASGPTSN-KWSNRTCSTQRRVERHRQQNEHLVLDNELKE-------------------------------------KYMQEARNLGKNLRQPKLSDLSPAVIAQTNWKFVEGLLKECKMKTKRMLVEKMGREAVELGHGEANITGLEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLHYQAREEKN----------------------------------------------EQQLESPVSNGQER-RKTESSVGLPGLR---VSVIQDMRHIQNMAEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQALTKKLYKRYAFLRCEEEKEQFLFHLLSLNAVDYFCFTSVFTTIMIPYRAVIIPIKKLSNAMTTSNPWLCVSGELGDSGILQITKNILEMTFDCQNLGKLTTVQLGHDNSGLLAKWLVDCVMVRNEITGHTYKFPCGRWLGKGVDDGSLERVLIGEFVVP-CGDDEGGRGS--KTPPLQRSPSQIRRISITSLTGKGNKPTTVQIQESIGEAVNNIIKHFHKPEKER--GSLTVLLCGEGGLVWALEQFFHHGFRSARIFQKNVFVWDFFERIVAFMENRDQTGDLQESP----------------EPLSLNSESLCRYVNAINNMP-RNIGKDGKFQLLVCLGARDRLLPQWLPLLAESPVITRMYEENALLRDKLTVSSLLGVLETLHDFPITLETSLTKSVEL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0E1-1", "uniprot_id": "Q9W0E1_DROME", "id": "Q9W0E1-1", "name": "", "aln": "MTTRENVVSSRLSKLMLSSGSGNGSGNGSGPNIQVAPSSTLVQSPTSPGEQSQSQSELNQLKRDADPQFSRFADYFVICGLDLDTGLEPDRFA--------------------GDNLHCSPLDRAYKSKPLAHYPENVPWNPFDAHGICMLSLPQGLRFRTQKHCIEPRFHSFATTREDGKRCYGFSLVFYEEIRNRNICGAIHTLQSMFITELS---------NGQQTHSLSRVKQDGPVSRSLPRHFKVAGQAPQSAQSYYDINKDKLYVAKSITLICQAPYAFAAQMFLKNLYRCLPRQPGAGISLESYVYNILYEVMLPQPGKSIRVYLPPTEPHLPPIALILQRPLLATELPLLDFPLRLLFKYLGVECVIQLLTCVLLENQVLLRSTDYQRLMIVGECITSLLFPFVWPHVYAPILPAALHHFLDAPVPFVMGLHAECEAAH---KIGSEATLCFVDIDKKHIQLPEELPVFPHKVDFMAEIGSVLDKFEIERDRDQEPSFRNGYVGRGAGGGVSGSGSSGSGGVDAMISSCTLPTGLQAARRSKERFQQMQETVYTLSGSPGGGVVDYQPLIAHPSRIDHVPRIADFLRRKGGIRGAGSPVGSPTVSLSSSPVGIYHDVDAVDATMPVSTRRAEKQKLSPVDQYYQDLRINNSVREIFLNRFVHMFHAYEYFVIYPNQARDEWISNRETLQNFDKSSFLSDQPEHHRAFLSRFLESQMFATLIDNKILAMWESQPDEQLQLFDQRVKLLRRRHG-ENMIAATSYEPCVLSQDSQQGFEKRLNCIDIEVTPP--SEILANRAAYFR-SFPLLEKGVLNQ------ECASRGNSLRRVKNGNKWRAREISLDQKPGS----------------------------------------NAINRLSANLTT---ADVSPALIAQANWTFVERLLKDIKSKTKRMLLEKMGNEAVALGLKGD---GIEENTLIASMCDLLEKIWSHGLQNKQGKSALWAHLQAYLEMQEARGAGDSSGTEQTPPVSSSPGGKMTIATASPALAWNAMRKRMDYLSTFQTDFDSPPSPNRSRSRDRNKFVGLEQLCPLPESLEFDVKNVLAMADIKTHIGYTRAWVRLSLEKKLLSRHFRTLLSDEALLRSLYKRSAFLRCEEEKEQFLYHLLTLNTVDYFSFTNIYPTTKLPYRVVIFPSRKYGSYHTSSNVWIMVSGTMNETQRVPVPKGSLEFIFHYKNLGLLTTMRIGHDNSGPSHKWLVEQVVMRNEVTGHTYKFPCGRWLGRGVDDDSTERLLVGQRVLTNAKNAELVPGSDTRTPPRTRSPSVQRQETLAPS----------EIQHQLGNCVNVLVKWHYKPSRDRDVGTLTNLLCGDDGLVKCLEQVFLCGFRSARFFGRNLYIWDYFTKIKELFEHNLQMELEDSSSSLDSSFSNGSGSGGNSLQRREISSIWRLYVQLMDEINGTALGKDGKFQLLICLSLREHLLTRLIKPMALTKVTHEMYEEESFLRRRNLLTFLIQILEPLDDCHIVLENSITQGIRIASQC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: .**.. .***.**::**:* ::***** :* *:*:. *** *::*** *****:*: **** ..: **.:*:** **** . *:**** *****.* *** .****: . :** *::** .*. :* .. : * . *. :: *: : : . ** :*.***:*:: ** *: *.: ** ::::.:. . . :.****::*:**** ** .*:*::.: ** :: *** **** *:** . **:* ::*::****** * ** * ****** *.* **:***** * ***.*****:* ********::***::: : : :: .**.*******:: *:***::* **:: :*: *:..** .* : :* . . .. :::: : .*. :. *: : *: : :*.* * :. :: . : : :: ::* .:**:* **. ** ** *** :.*::.** ::****:******** : .***:*:*:*****:*****:: **.: : *::** *:. * : : :: *: * ::: *.:*:** :* . * :: .:. * : ** *: .** . .* : :* : : ..: **.. . : . *. ** :*:***:***:* .*** ***: : ******:****.*** ** *:********:*****:****** ********:** : :* . : :** : . .* *. :. * * * *: *:::: *::***.:* :***:**********:*:: ***::.* :.**** ********:****:***:**:****.**.::.* :*** **:* :* .. :** *: *** :.:: : :.*. **: *. :*** ***:::****** ****: *::***:*****:********:*:**.* **:*:*: : . . : : . :*** :**: *: :::. :**. :*:.** ::* .:**.::* *:** ****:.*** .***.* **:***:* :*:::**:. : :* * : . .. **: :: :*******:*:**. *::**.: : :* . .****.::** : :. *: :*:.:.* *.** *: :.: : ", "identical_positions": 507, "similar_positions": 371, "identity": "32.77%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2249", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q13151-1", "uniprot_id": "ROA0_HUMAN", "id": "Q13151-1", "name": "Heterogeneous nuclear ribonucleoprotein A0", "aln": "----MENSQLCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMAASPHAVDGNTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAEGDLIEHFSQFGTVEKAEIIADKQSGKKRGFGFVYFQNHDAADKAAVVKFHPIQGHRVEVKKAVPKEDIYSGGGGG-GSRSSRGG---RGGRGRGGGRDQNGLSKGGGGG---YNSYGG--YGGGGGGGYNAYGG--GGGGS-SYGGSDYGNGFGGFG---SYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGPYRGGYGGGGG---YGGSSF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CX86-1", "uniprot_id": "ROA0_MOUSE", "id": "Q9CX86-1", "name": "Heterogeneous nuclear ribonucleoprotein A0", "aln": "----MENSQLCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMAASPHAVDGNTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAEGDLIEHFSQFGAVEKAEIIADKQSGKKRGFGFVYFQSHDAADKAAVVKFHPIQGHRVEVKKAVPKEDIHAGGGGARAARGGRGGGRGRGGGGGGGGRDQNGLAKGGGGGGGGYNSYGG--YGG-----YGAYGG--GGGGGGSYGGSDYGNGFGGFG---SYSQHQSSYGPMKSGGGGGGGGS-WGGRSNSGPYRGGYGGG-----YGGGSF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QS28-1", "uniprot_id": "F1QS28_DANRE", "id": "F1QS28-1", "name": "", "aln": "MTAQMEN-QLCKLFVGGLNVQTTDDGLRNHFEQYGKLTDCVVVQNQQLKRSRCFGFVTYSSPDEADSAMSARPHILDGNNVELKRAVAREDAGKPEALAKVKKIFIGGLKDDIEEDHLRDCFSQFGAVEKAEVITDKETGKKRGFGFVYFEDNDSADKAVVLKFHIINGHKVEVKKALTKQEMQAAGSRG-GGRGGRGG-------GRGMGRPQNGYG-GRGGG---YGNYGGGGYGG-----NDGYGGGYGGGYGGGYGGG-YGDQMEGYGGGNGYNDFGSGYG-QQSSGYGPMKGN-YSGRSNAPYSRGGGGGGYGRGGYGGSY-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** ******:*******::.***.*** :*.******* * * ************. :***:**:* ** :***.*******:***:.:* * *****:*:****.*: *..* : *****:*****:*:**::***********:.:*:****.*:*** *:**:******:.*::: :.*. . ..*..*** * * ** *** . * *** *..*** *** ..*** *** . .***. **: : *:* .*.:. *.** :*.* * *. :.****: *** *** ***. ", "identical_positions": 180, "similar_positions": 73, "identity": "55.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2258", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C0P5-1", "uniprot_id": "COR2A_MOUSE", "id": "Q8C0P5-1", "name": "Coronin-2A", "aln": "-------------------MSWHPQYRSSKFRHVYGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQTGKLDPHYPKVCGHRGNVLDIKWNPFNDFEIASCSEDATIKIWNIPKQLLTRNLT---------TYRKELIGHARRVGLVEWHPTTANILFSAGYDYKVMVWNLDTKDSVIAGPVKTINCHQDVILSMSFNTNGSLLATTCKDRKIRIVDPRLG-IVLQEASYKGHRANKVLFLGSLKKLLSTGTSRWNNRQMALWDQENLSVP--LTEEDLDGSSGVLFPFFDSDTSMLYIVGKGDGNIRYYEVSMEKPHLTYLTEYRSYNPQKGIGIMPKRGLDVSSCEIFRFYKLITTKSLIEPVSMIVPRRSESYQEDIYPPTAAAQPSLTAHEWLSG-MNRGPIMMSLR---PGSELLDSQTLPPERPLSNSMVQVSPQPLEPMKQPAEDGDQ-------APFSLLEEKLAKWTAEHHLGEK---SCLTNG-FDVFECSPPKTENELLQMFYRQQEE--------------IRRLRELLIQREVQTKQLELEIKNLRMALGQL------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2QC56-1", "uniprot_id": "A0A0G2QC56_RAT", "id": "A0A0G2QC56-1", "name": "Coronin", "aln": "MWNGNSKLRPSPPLLKPNQMSWHPQYRSSKFRHVYGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQTGKLDPHYPKVCGHRGNVLDIKWNPFDDFEIASCSEDATIKIWNIPKQLLTRNLT---------TYRKELMGHARRVGLVEWHPTTANILFSAGYDYKVMVWNLDTKDSVISGPVRTINCHQDVILSMSFNTNGSLLATTCKDRKIRIVDPRLG-IVLQEASYKGHRANKVLFLGNLKKLLSTGTSRWNNRQMALWDQDNLSVP--LTEEDLDGSSGVLFPFFDSDTSMLYIVGKGDGNIRYYEVSTEKPHLTYLTEYRSYNPQKGIGIMPKRGLDVSSCEIFRFYKLITTKSLIEPVSMIVPRRSESYQEDIYPPTAAAQPSLTAHEWLSG-MNRGPIMMSLR---PGSELLDPQALPPERLLSNSVVQVSPQPLEPVKQPAEDGDQ-------APFSLLEEKVTKWTTEHQLEEK---SWLTNG-FDIFECPPPKTENELLQMFYRQQEE--------------IRRLRELLIQREVQTKQLELEIKNLRMVLGQF------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92828-1", "uniprot_id": "COR2A_HUMAN", "id": "Q92828-1", "name": "Coronin-2A", "aln": "-------------------MSWHPQYRSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQTGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLT---------AYRKELVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLATTCKDRKIRVIDPRAG-TVLQEASYKGHRASKVLFLGNLKKLMSTGTSRWNNRQVALWDQDNLSVP--LMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEVSADKPHLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRRSESYQEDIYPPTAGAQPSLTAQEWLSG-MNRDPILVSLR---PGSELLRPHPLPAERPIFNSMAPASPRLLNQTEKLAAEDGW-------RSSSLLEEKMPRWAAEHRLEEKK--TWLTNG-FDVFECPPPKTENELLQMFYRQQEE--------------IRRLRELLTQREVQAKQLELEIKNLRMGSEQL------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QR96-1", "uniprot_id": "F1QR96_DANRE", "id": "F1QR96-1", "name": "Coronin", "aln": "--------------MTITKMTWRPQYRSSKYRHVFGKPATKENCYDGVPITRSVHDNQLCAANPRFIAVITECAGGGSFLVLPVHHTGKVDPHHPKVSGHRGNVLDIKWNHFNDFCIASCSEDATVKIWEIPEHGVLKTIT---------VPWKELQGHSRRVGLIEWHPTANNIIFSTGYDYQVMVWKLDVPEQVIKNPVRSISVHSDVVLSMSFNTDGSKLATSCKDKKIRVIDPRTG-TILQETNCKSHKASKVLFLGNLKMLLSTGNSRWNHRQIALWDQEDLSQP--SYSEDLDGSSGVLFPFYDPDTHMLYIAGKGDGNIRYYEISPEKPYVHYLTEYRSHLPQKGMGVMPKRGLDVCSCEIFRFYKLVTIKSLIEPLSMIVPRRSESYQEDIYPMTAGNKPAMTANEWISG-LDKGPVMMSLR---PGSKVDTYVELGLKKSPMESTEMHNSRSQPGLSQLIQRLET-------KDGNGRKESHPTLLLPSTEENGSSASHVSNGQLDSPHCSPPKTENELRQMFYKQQEE--------------IRKMRELLNQKDVRIKQLELEIKNVRNSQAPL------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06440-1", "uniprot_id": "CORO_YEAST", "id": "Q06440-1", "name": "Coronin-like protein", "aln": "--------------------MSGKFVRASKYRHVFGQAAKKELQYEKLKVTNNAWDSNLLKTNGKFIAVNWNASGGGAFAVIPIEEVGKAPDQVPLFRGHTAQVLDTDFDPFNDHRIASGSDDSKIGIWDIPENYKFHDHVDEDGEPIDIKPVKFLTGHARKVGHVLYHPVAENVLASSSGDYTVKLWNVETGKDMIT------LKHPDMVTSMSFSYDGNYLATVARDKKLRVWNIREEKIVSEGPAHTGAKNQRVVWLGNSDRLATTGFSKLSDRQIGIWDAFNIEKGDLGGFYTVDQSSGILMPFYDEGNKILYLVGKGDGNIRYYEFQNDE--LFELSEFQSTEAQRGFAVAPKRMVNVKENEVLKGFKTVVDQR-IEPVSFFVPRRSEEFQEDIYPDAPSNKPALTAEEWFSGKSVEGPILVSMRSIYDGSAPSFHEAKRPQQPTTQETALEEKKEQPKVEKPISESEKEVKQEAPKSPSPLKSASSSSTINHVLKEDNSINKLLKKSSDIDQVNNAEDPSRDTSGWEEADDEPAPIKIETPVTPTETKKDRTPKVEPSKELKPEPVSIATDRKQEQSLPQEEKSSEKTKSPEQEKSATPPSSITAAKTAITASSKEEPSAARTSPKSLGLKKSVEKLSTLVLQLEDVVDKLTKANLDKDERLLKLEQKIGELSK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:**:***:*:.*.** *: : :*... *.:: .* :**** :.:***:* *:*:...** : * . ** .:*** .:: *:*. *** *:*:.: **.**:: : . * * **:*:** : :**.: *:: *:. ** * :*:::. ..:* * *:: ****. :*. *** .:*:*:*: : * : : . .. : .:*::**. . * :** *: ..**:.:** ::. :* ***:*:**:* .. :**:.***********.. :: : *:*::* .*:*:.: *** ::* . *::: :* :. : ***:*::******.:****** :.. :*::**.**:** ..*:::*:* ** :: :. . : .: . :. . : . : : * . .: .. . : . ::* :: * : . . * :.* . * : ", "identical_positions": 150, "similar_positions": 181, "identity": "22.06%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2260", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59817-1", "uniprot_id": "Z280A_HUMAN", "id": "P59817-1", "name": "Zinc finger protein 280A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDIFLC---KKVESPKK-----------NLRESKQRE--EDDEDPDLIYVGVEHV-----HRDAE-------VLFVGMISNSKPVVS-------------------NILNR----VTPGSNSRRKK-GHFRQYPAHVSQPANH--VTSMAKAIMPVSL---SEGRSTDSPVTMKSSS----EPGYKMSSPQVVSPSSSDSLPP------GTQCLVGAMVSGGG----------RNESSPDSKRLSTSDINSRDSKRVKLRDG----IPGVPSLAVVPSDMSSTISTN--TPSQG--------ICNSSNHVQNGVTFP--WPDANGKAHFNLTDPER-----------ASESALAMTDISSLASQNKTFDPKKENPIVLLS---------DFYYGQHKG--------DGQPEQKTHTTFKCLSCVKVLKN-IKFMNHMKHHLEFEKQRND-SWEDHTTCQHCHRQFPTPFQLQCHIDSVHIAM-----GPSAVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSSVFADVETHFRTCHENTKNLLCLFCLKLFKTAIP----------YMNHCWRHSRRR--VLQCSKCRLQFLTLKEEIEHKTKDHQTFKKPEQLQGLPSETKVIIQTSVQ------------------------PGSSGMASV-------------IVSNTDPQSSPVKTKKKTAMNTRDSRLPCSKDSS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86YH2-1", "uniprot_id": "Z280B_HUMAN", "id": "Q86YH2-1", "name": "Zinc finger protein 280B", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEQSCEE---EKEPEPQK-----------NIQETKQ----VDDEDAELIFVGVEHV-----NEDAE-------LIFVGVTSNSKPVVS-------------------NILNR----VTPGSWSRRKKYDHLRKDTARKLQPKSHETVTSEAVTVLPASQ---LESRSTDSPIIIEPLS----KPDYRNSSPQVVPNNSSELPSPLITFTDSLHHPVSTALSVGG----------INESPRVSKQLSTFEVNSINPKRAKLRDG----IIEGNSSASFPSDTFHTMNTQQSTPSNN--------VHTSLSHVQNGAPFP--AAFPKDNIHFKPINTNL-----------DRANELAKTDILSLTSQNKTFDPKKENPIVLLS---------DFYYGQHKG--------EGQPEQKTHTTFKCLSCVKVLKN-VKFMNHVKHHLEFEKQRND-SWENHTTCQHCHRQFPTPFQLQCHIENVHTAQ-----EPSTVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSSVFADVETHFRTCHENTKNLLCPFCLKIFKTATP----------YMCHYRGHWGKS--AHQCSKCRLQFLTFKEKMEHKTQCHQMFKKPKQLEGLPPETKVTIQVSLEPLQ---------------------PGSVDVASI-------------TVSTSDSEPSLPRSKSKISKKSH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZNU4-1", "uniprot_id": "D3ZNU4_RAT", "id": "D3ZNU4-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEQPYVVDDDESDPEPQP-----------RSQEPIQVLDEDDSEDAELIFVGVENV-----KEDAE-------LIFVGVTSTSQPANS-------------------NILNR----VTPGSRLKRKH-DRLRETTTQRLQPSPPAAPTSEAAIVLPVSP---AESRSTDSPIIIEPLS----ESDYK-SNSQVVPSSSSKCCSPLATLSSSESGPARAACSGGG----------LNESLYVSK--CHFSIN---PQRPERSIE----IVEELSSALPPSGPFHTSNAQQRTPSLE--------APKSLNLFVNGAPLS--G---------DPVHPRQ-----------DSGS--VDTDFSSLASP-ETFDPKKGSLTLLLS---------DFYYGQYKG--------EGKPEQKTHTTFKCPSCSKALKN-VKFMNHTKHHLELERQGSDEAWESHTTCLRCHRLFASPFQLECHIDRVHTAP-----DPCVVCKICELSFETEQVLLEHMKDNHKPGEMPYVCQVCKYRSSVFADVETHFTKCHVNTKNLLCPFCLKIFRTGMP----------YMCHCRGHWERN--GHQCSKCRLQFLTFKEKMEHKTQCHQMFRKPKQLEGLPPETKVVIQVSVKPVE---------------------AESVEVASI-------------TVSTTDWEPSCPRSQGRLSQKPH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LVH6-1", "uniprot_id": "A0ABK0LVH6_RAT", "id": "A0ABK0LVH6-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGVGNRRTWVLQKS------------NNLKMAELFMECEEEELEPWQKKVKEV---EEDDDDE-------PIFVAEIASSKPAIS-------------------NILNR----VNPSSHSRGIKNGILNRGFTASFKPTSQRCPNSASNPVAALPVNFHPESRSSDSSVIVQPFS----KPGYVTNSPRVLSSNPSELLFDLTQDTGLSHYQGGPTLSIAG----------LNETSFLSKRPSGSDISSVNPKKPKPNEN----ISGTDASSVVSSEKSPSVMSLQVVPSQG--------TNCSSNQSKNGTTFP--RACPKCNIHFNLLDPLKNHMTYCCPDMINNFLGLTKTDNLNSANEAKTLDSEKGKLIMLVN---------DFYYGKYEG--------DVQEEQKTHTTFKCFSCLKVLKNNIRFMNHMKHHLELEKQSSE-SWEKHTTCQHCYRQFPTPFQLQCHIESTHTPH-----EFSTICKICELSFETEQILLQHMKDNHKPGEMPYICQVCNYRSSLFSEVESHFRTSHENTKNLLCPFCLKVIKIATP----------YMHHYMKHQKKG--IHRCTKCRLQFLTCKEKMDHKTQHHRTFVKPKQLEGLPPGTKVTIRASVAPLQSGSSVTP-SISASTSTLQLSPPRTENVTAK----------NHVKLNTSTPNTTISDPSKTNEIKSNGSKSKNRSKVSNMQKKQSTLSNSNKKSKVNTALRNLRLRRGVHECIECSSEVKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPSKRYCIFKKHSENLRGISLVCLNCDFLTDVSGLDNMATHLSQHETHTCQVLVEKVSVCIPTSERLSELKTEAPTKGQESVSKETARHSTAEREPGASHSESKQDKAPPSEDDTGRDASVCEAAAAANRERNVTASDTED-------VRTSNDVLSRGPEVGTDNMEKEEQAHHTCQEMELKRDQSSE--STDDQSKEHSPTEAELSSEISQDLQLTPEGVGLGQCLRQGEEPESVNSDASEQDSVRLEPLTPSEVLEFEATEVCHSGE-DPSASTSDAVSGGTGGSPGGSSPRRAESAADLAGGQEGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q68FE8-1", "uniprot_id": "Z280D_MOUSE", "id": "Q68FE8-1", "name": "Zinc finger protein 280D", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVTTYIKSDLQLDGRQFFQPK------------DNLKMAELFMECEEEELEPWQKKVKEV---EEDDDDE-------PIFVAEIASSKPAIS-------------------NILNR----VNPSSHSRGIKNGILNRGFTASFKPTSQRCLNSASNPVAALPVNFHPESRSSDSSVIVQPFS----KPGYVTNSPRVLSNNSSELLFDLTQDTGLSHYQGGPTLSIAG----------LNETSFLSKRPSGSDISSVNPKKPKPSEN----TSGIDASSVISSEKSPSVISLQVVPSQG--------ANCSSSQSKNGTTFP--RACPKCDIHFNLLDPLKNHMTYCCPDMINNFLGLTKADNLNSANEAKTLESEKGKLIMLVN---------DFYYGKHEG--------DVLEEQKTHTTFKCFSCLKVLKNNIRFMNHMKHHLELEKQSSE-SWEKHTTCQHCYRQFPTPFQLQCHIESTHTPH-----EFSTICKICELSFETEQILLQHMKDNHKPGEMPYICQVCNYRSSLFSEVESHFRTSHENTKNLLCPFCLKVIKIATP----------YMHHYMKHQKKG--IHRCTKCRLQFLTCKEKMDHKTQHHRTFVKPKQLEGLPPGTKVTIRASVGPLQSGSSVTP-SISPSTSTLQLSPPEPDNVTAK----------NHVKLTTSTPNTTISDPSKANETKSNGSKSKNKSKVSNMQKKQSTLSSSNKKSKVNTALRNLRLRRGVHECIECSSEVKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPSKRYCIFKKHSENLRGISLVCLNCDFLTDVSGLDNMATHLSQHETHSCRVLVEQVSVCIPTSERLSEIKTEAPTKGQEPVSKETARHSRAEGEPGASHSGSKQDKVPSSEEGTGCDASVCEAAAATHCEKDVTVSDTEN-------VSSSKNILSHDPDVGTDTMEKEEKTHHACQEMELKVDQSSE--STN-------PTEAELSSETRQGLQLTSGDVGIDQFLRQGDEPKSVNSDASDPGSVRLEPLTPSEVLEYEATEILHDGD-DPSANTSDTVSDQTGGSPGGSNPCRAETAVDLADGEERS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6N043-1", "uniprot_id": "Z280D_HUMAN", "id": "Q6N043-1", "name": "Zinc finger protein 280D", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDNPFQPK------------SNSKMAELFMECEEEELEPWQKKVKEV---EDDDDDE-------PIFVGEISSSKPAIS-------------------NILNR----VNPSSYSRGLKNGALSRGITAAFKPTSQHYTNPTSNPVPASPINFHPESRSSDSSVIVQPFS----KPGYITNSSRVVSNKSSELLFDLTQDTGLSHYQGGPTLSMAG----------MSESSFLSKRPSTSEVNNVNPKKPKPSES----VSGANSSAVLPSVKSPSVTSSQAMLAKG--------TNTSSNQSKNGTPFP--RACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLAKTEFSSTVNKNTTIDSEKGKLIMLVN---------DFYYGKHEG--------DVQEEQKTHTTFKCFSCLKILKNNIRFMNHMKHHLELEKQSSE-SWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-----EFSTICKICELSFETEHVLLQHMKDNHKPGEMPYVCQVCNYRSSSFSDVETHFRTSHENTKNLLCPFCLKVIKIATP----------YMHHYMKHQKKG--IHRCTKCRLQFLTCKEKMDHKTQHHRTFIKPKQLEGLPPGTKVTIRASVGPLQSGASPTP-SISASASTLQLSPPRTKNITAK----------NPAKSNTSKPNTVKSNASKPNTSKPNGSKSKYKPKISNMQKKQSTLASSNKKSKVNTALRNLRYRRGIHKCIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPSKRFCIFKKHSENLRGITLVCLNCDFLSDVSGLDNMATHLSQHKTHTCQVVMQKVSVCIPTSEHLSELKKEAPAKEQEPVSKEIARPNMAERETETSNSESKQDKAASSKEKNGCNANSFEGSSTTKSEESITVSDKENETCLADQETGSKNIVSCDSNIGADKVEKKKQIQHVCQEMELKMCQSSENIILSDQIKDHNSSEARFSSKNIKDLRLASDNVSIDQFLRKRHEPESVSSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSGDPSAKTDEVVSDQTDDIPGGNNPSTTEATVDLEDEKERS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6B2J6-1", "uniprot_id": "A0A8I6B2J6_RAT", "id": "A0A8I6B2J6-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDKDNSVQEKSPGTEIQVDRLGDNSKMAELIMECEEEELEPWQQKVEES---QNKDDDDDDD---ELIFVGEISSSKPAISIMC----------FCKILVDILNR----CSPGSSSKGLKNGSFSPALSNIFKPTNQHYRNPPSHPLIALPS-FYPAPKSSESSD-VQTVS----KPTFLKTSPQDDSGASSASLLDSTKD--IPSSN---VLQKST----------GVNQTLRLKHPSSSKVNSVNPKKPKTNAS----ISETGRGSASSLNMSPSEASSQVVLSN---------MNTSSIQSAAGKPSL--RSCPKCNVKFSLLDPLKCHMKRCCPDMINKFLETLKSENSKAVSRAI-IGSDKEKLIMLVS---------DFYYGRHEG--------TIEEDQKAPTTFKCFSCTKVLKNNIRFMNHMKHHLEFEKQNNE-TWESHTTCQHCYRQYPNPFQLQCHIESTHTPH-----DFSTICKICELSFETEHLLLQHMKDTHKPGEMPYICQVCQFRSSIFSDVETHFRSSHENTKNLLCPFCLKVSRMATP----------YMNHYMRHQKKG--IYRCPKCRLQFLTSKEKIDHKLEHR-TFIKPKELEGLPPGTKVTIRASLGSIQSRSSSPPSSTIPSTS-LQLSVPKSKTTTTKNTTTKNNSKVSANKVTTTSPQTMSTTTGKTNASKPGTGTTKSKAKPSNKQKRQ-----RTRKNKFSIDLRNLRCHQGTHTCIECHSKIKDFSSHFSTYINCDFCKYTTNCNKAFTNHMSS-HNDHPSKQLCIFKKHSRALRGITLVCLKCDFLADTSGLDRMAKHLNQRKTHTCQVVIENVTERTGTSESTSDGLLK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P3Y5-1", "uniprot_id": "Z280C_MOUSE", "id": "Q6P3Y5-1", "name": "Zinc finger protein 280C", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDKDNSVQEK--GLFLSSWKL-DNSKMAELFMECEEEELEPWQQKVEES---QSKDDDD------ELIFVGEISSSKPAIS-------------------NILNR----CSPGSSSKGLKNGSFNPAISNIFKPTSQHYRNPSSNALVALPS-FHPALKSSESSD-GQTVS----KLDFTKTSPQEDSGACSVSQSDSTQD--IPSSN---ILQPRT----------GVDQTLGLKHPSTSKVNSVNPKKPKTSAS----ISETRPCSSSSSQTAPSGASSQTVLSN---------VNTSSVQSAPGSSSL--RSCPKCNVKFRLLDPLKCHMKRCCPDMINKFLETLKSENSKAVSKAT-TDSDKEKLIMLVS---------DFYYGRHEG--------TIEESQKTHTTFKCFSCTKVLKNNIRFMNHMKHHLELEKQNNE-TWESHTTCQHCYRQYPNPFQLQCHIESTHTPH-----DFSTICKICELSFETEHMLLQHMKDTHKPGEMPYICQVCQFRSSIFSDVETHFRSSHENTKNLLCPFCLKVSRMATP----------YMNHYMRHQKKG--IYRCPKCRLQFLTSKEKTEHKLEHR-TFIKPKELEGLPPGTKVIIRASLGSSQSRASSPPSSTIPSTS-LQLSVPKSKSTTTK-----NNSKVSANKATTTSPQTVATTTGKPSASKPGTGTTKSKAKPSYKQKRQ-----RTRKNKFSIDLKNLRCHQGSHMCIECRSKIKDFSSHFSTHINCDFCKYTTNCNKAFTNHMSS-HNDHPSKQLYIFKKQSRARRGITLVCLKCDFLADTSGLDRMAKHLNQRKTHTCQVVIENVTERAVTSESASDGLFK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8ND82-1", "uniprot_id": "Z280C_HUMAN", "id": "Q8ND82-1", "name": "Zinc finger protein 280C", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDDDKPFQPK------------NISKMAELFMECEEEELEPWQKKVEET---QDEDDDE-------LIFVGEISSSKPAIS-------------------NILNR----GHSSSSSKGIKSEPHSPGIPEIFRTASQRCRDPPSNPVAASPR-FHLVSKSSQSSVTVENAS----KPDFTKNS-QVGSDNSSILLFDSTQES-LPPSQDIPAIFREG----------MKNTSYVLKHPSTSKVNSVTPKKPKTSED----VPQINPSTSLPLIGSPPVTSSQVMLSK---------GTNTSSPYDAGADYL--RACPKCNVQFNLLDPLKYHMKHCCPDMITKFLGVIVK-SERPCDEDK-TDSETGKLIMLVN---------EFYYGRHEG--------VTEKEPKTYTTFKCFSCSKVLKNNIRFMNHMKHHLELEKQNNE-SWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-----EFSTICKICELSFETEHILLQHMKDTHKPGEMPYVCQVCQFRSSTFSDVEAHFRAAHENTKNLLCPFCLKVSKMATP----------YMNHYMKHQKKG--VHRCPKCRLQFLTSKEKAEHKAQHR-TFIKPKELEGLPPGAKVTIRASLGPLQSKLPTAPFGCAPGTSFLQVTPPTSQNTTAR-----NPRKSNASRSKTSKLHATTSTASKVNTSKPRGRIAKSKAKPSYKQKRQ-----RNRKNKMSLALKNIRCRRGIHKCIECHSKIKDFASHFSIYIHCSFCKYNTNCNKAFVNHMMSSHSNHPGKRFCIFKKHSGTLRGITLVCLKCDFLADSSGLDRMAKHLSQRKTHTCQVIIENVSKSTSTSEPTTGCSLK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BDY8-1", "uniprot_id": "A0A8M2BDY8_DANRE", "id": "A0A8M2BDY8-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSELFMECEEEELEPWQKAIPEINLIDLDDDDEDDD---EPIFVGEICSSKPAAQKKS----------VAANQQNQRNVPVQKPATVTTVQNTPQAPLNPPRVAAGPTIMVRSTAPSGGNPILIPLNTTLGPQTAPQPIIINNQGYIVASPQNLNSNTSFISSLGSQYPPGTTFTVVQAGQQIVPQVSVAPKPGV------IHRPQVKLIQDNVVTLSNVQAPANHSSQSRTISVSQNTPGIIPTTLLKPKTSSMQIMNSRADNGKVINEANNSVSKGAGEKNLIGTRKCPRCQNVF-PLEPLKIHMKLCCPELWDSVFPSTSR-PDKQIITPKVVESDKGKLIMLVS---------DFYYGKSDGD------PSLMPKIKSNTTFKCNSCLKMLKNNIRFMNHMKHHLELEKQNSE-SWESHTTCQHCYRQYSTPFQLQCHIESAHSPF-----ESSTNCKICELAFETEQVLLEHMRDNHKPGEMPYGCQVCNYRSSFFCDVDNHFRTVHENTKDLLCPFCLKVLRSGHM----------YMQHYMRHQKKG--IQRCGKCRLNFLTYKEKVEHKIHFHRTYRKPRNLEGLPPGTKVTIRASISG----------------------APMSTESSSK-----------SYIIPTSPESTKQPFRTSPNSTKPN--VNGGKAKTANQFNWN--------RCLYNTELKRLKLPKGDNKCMECLHDVVDPYIHYPLSLKCNKCKYRSSCQKAFRQHMIRFHQNSTKVRVGKVKNPPRGVRSLTLVCLKCDFLADASGADKMTEHLLSRSNHSCQVIMEPVSNGGPETNSSEDIHDDS--------KHLAPIQPHTEARDETEPIQSSEIQTIPDEDTVIEDG-------------------------------------SEAPEADKDDMDEVKEDMEEATTNEASVEESPKSLPPESPAEAPVCPVSALADEG---------AVTPSDFLCKTDGLDAGNADS------QLEPLTPSKVLEDDTTENNKQVETDG-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KER0-1", "uniprot_id": "A0A0B4KER0_DROME", "id": "A0A0B4KER0-1", "name": "", "aln": "MTRVTRSEISLDMEFWVEELSPAQLAYYEKITNEHNAVKGALKNAVSANEGKELFNGQVFQAYSFKGKVLQELKEATLPKKPPKPTDSPSTPAAQSGGTGRGRGRPPRQPSNIAYLESSDEGDDDMPLAKRLALSAGKKAVAVANASSSFTPKSSKKAASAASGGSSSPVPKSSGKLFKESKPDIESPPKNYRPAEVNSVGGLVVGSTDESKDSKDGKDGKDNKMQGKTYPSLVVLAKPFLKIKDMAATRSKLDSKVKLVLMLTPNKFCEWLLQEGLLRAQQHCINHRNNELKLGIYSDVTKFPYTGGYVWISECCPYRFVSVFNNSIFEGAQHPPTFLLKLIYHWACQTSIQNVVQWVKVDSVYIKGIYTWLRAICTLAVHQKCKKLGGPGKFVEVGVISLGTTSQDGSQRQVKVEVLGVYDYAEKSIRLRAVEPITDGDRNYKKRFQAILEPLSRWVHKDSTICIDLTVDKITLFSMGFKNIVQAAATDNTAKHNN--SAVMEYLRRIVPRMFQNTLSLLSRQMIQQFLDELVWRESFGTYALQAFNNIIIHIAEQTRVTTNETITQRLYQVATNPFKDWSILPANYKETPANAAPKRLKKPINDADYVVSNKIPKKEKDRDIASSGVKRGRPPNALGTPPPQLPIKKGPGRPPGSTNQTKGDRATTSSSKSLSKSLIAKGLGKKPKEKDEKIPMVIKKEEDDLRGLEELYYGISDGTDEYHEIFPYSTPRTVHNELAKTVECPICLNGDSFDSNEKLQTHLVSHISPEGKQHQFQCLFCLEKHPTESVLAKHNQIMHPTETKTEGSPSYYCLICQQRHNSLHLLTAHLQKVHSTLELPYWCHSCGYRSSSHRDLVRHFYDDHKHQNFLQCPYCLDIFYFSKLGVVNQLRIEHYFMHLDEHINKRDPSLRCQKCSLSFLEKGDLKQHAVQHHVSMTKTNRPVRLLLNNSMLIP----------------------------PPKIRTHHR----------EQPPFSTYKRPVFFAFLEGKTCAECNTDFASEETHYTG------------WLHCVKCNYQTCCERAQFRHGVECNGNFVDAMEVNMPQEMHCICGFATGNGNKMAQHLANCGLSTCYPSLEAASENAVKRNMLDMLGLVRRDGETSGEGADISETADDVADQSSDMLPPQEDHHLQQHHQQVGHQQQMQGQPNEPQAELQQEYLSAPVEHEPVQNMPVHQSMPVQQTG---------------------------------------PIQFGEMEAAPVLLDTQQQVQPTPDYAQVSVVQQHQQQQPYGLSNYGQSSLATDIDMPLIGELSEPNAPPTPQFLGEVHTPMFDAVAAAEQQHYHAQHHHHPQXYKPHGKLKSRDYTLHWQNY----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . : . . . : *. . . . . . . ::: : . . . : : . . :: . ::*** .* . . : * * .: * : .: : . : : * * . ... * * : * . . * **: .:: ::* *::. *.. *:** *: * :*** . :: ** * : : * * :**.: . *: * * : :* ** *.** : :* . : *... * .: * . . : ", "identical_positions": 47, "similar_positions": 90, "identity": "3.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2279", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99622-1", "uniprot_id": "C10_HUMAN", "id": "Q99622-1", "name": "Protein C10", "aln": "MASASTQPAALSAEQAKVVLAEVIQAFSAPENAVRMDEARDNACNDMGKMLQFVLPVATQIQQEVIKAYGFSCDGEGVLKFARLVKSYEAQDPEIASLSGKLKALFLPPMTLPPHGPAAGGSVAAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35127-1", "uniprot_id": "C10_MOUSE", "id": "O35127-1", "name": "Protein C10", "aln": "MASASAQPAALSAEQAKVVLAEVIQAFSAPENAVRMDEARDNACNDMGKMLQFVLPVATQIQQEVIKAYGFSCDGEGVLKFARLVKSYEAQDPEIASLSGKLKALFLPPMTLPPHGPASGSSVAAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6TH01-1", "uniprot_id": "C10_DANRE", "id": "Q6TH01-1", "name": "Protein C10", "aln": "MASAPAQQPTLTVEQARVVLSEVIQAFSVPENAARMEEARESACNDMGKMLQLVLPVATQIQQEVIKAYGFNNEGEGVLKFARLVKMYETQDPEIAAMSVKLKSLLLPPLSTPPIG--SG--IPTS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8DYT6-1", "uniprot_id": "A8DYT6_DROME", "id": "A8DYT6-1", "name": "Protein C10", "aln": "----MSYLTNFNSDTAKQILMDIIRCVNQPENSKKLSEAKASAGKEMILMMQHVFPLVMQLQLEVIKGHGFPGNREGLVQFSQLIREMERDDMEIVRLRSQIRAIYLPPIAINTTNDILI------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :. : *: :* ::*:... ***: ::.**: .* ::* *:* *:*:. *:* ****.:** : **:::*::*:: * :* **. : ::::: ***:: . . ", "identical_positions": 33, "similar_positions": 48, "identity": "26.19%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2281", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LJB9-1", "uniprot_id": "A0ABK0LJB9_RAT", "id": "A0ABK0LJB9-1", "name": "", "aln": "MQVPGVCLAAGWFLLALCLWGQPGEAAACHGCSSGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNQGYPGPPGIQGPPGPKGVSGPSGPPGPPGLMGPPGPPGPPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDLDFQ---KGDQGVPGDRGPPGPPGIPGPPGPPGGVKGEKGEPGEPGKRGKPGKDGETGQPGIPGLPGDPGYPGEPGRHGEKGQKGDTGPPGPPGFVIPTPGTGVTIGAKGNIGQPGLPGEKGERGFPGIQGPPGFPGPPGTAVMGPPGPPGYPGERGQKGDEGPPGICIPGSPGLDGQPGAPGFPGPPGPPGPQLPPSDEICKAGPPGPPGSPGDQGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGIPGEKGEKGQAGTTGPKGLPGIPGPPGAPGFPGSKGDPGDVLTLPGMKGEKGELGSPGAPGLPGLPGSPGKDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNMGPTGPVGFGPPGPVGEKGIQGVAGNPGQPGLPGPKGDPGQTISQPGKPGLPGNPGRDGEVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGPPGPPGPKGFPGIPGPPGPPGAPGRMGPEGPPGLPGFPGPKGEPGFGLPGPPGPPGFPGFKGTPGPKGDRGLPGPPGPPGHTGLDGLPGPKGDAGPNGQPGPIGPPGLPGIGLQGPPGPPGTPGPIGQPGLHGIPGEKGDPGPPGLDVPGLPGERGSPGLPGAPGLIGPPGSPGIPGRAGVPGFPGVKGEMGMMGPPGPPGPLGTPGRSGAPGLKGDDGMQGQPGLPGPVGEKGGKGEPGLPGPPGPMRPDFLGSKGEKGDPGLPGIPGLSGPKGYQGLPGDPGQPGLSGQPGSPGLPGPKGTPGLPGPPGLTGPPGPKGNIGDMGFPGPQGVDGPPGPPGGPGQPGSPGLPGQKGSKGEPGVSGIGLPGLPGPKGEPGLPGYPGNPGIKGSMGEAGLPGLPGSPGAKGQPGLPGFPGTPGLPGPKGMNGPPGNPGLPGEPGPVGGGGRPGPPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGIPGPPGLPGLSGQKGDGGAPGLPGNPGLPGSKGEPGFQGFPGMPGPPGPPGSPGPSLEGPKGNPGPQGPPGRPGPPGFQGPPGTEGPRGPPGNGGIKGERGNPGPPGQPGLPGLKGDQGPPGLPGNPGRPGLNGMKGDPGLPGVPGFPGMKGPIGVPGSTGPDGEPGLTGPPGPPGLPGPSGQSIVIKGDPGPPGIPGQPGLKGLPGLPGPQGLPGPIGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGSRGLDGPPGPDGLQGPPGPPGTTSVAHGFLITRHSQTTDAPQCPQGTVHIYDGFSLLYVQGNKRAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMNMEPLKGQSIQPFISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVDMSDMFSKPQSETLKAGDLRTRISRCQVCMKRT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q63ZW6-1", "uniprot_id": "CO4A5_MOUSE", "id": "Q63ZW6-1", "name": "Collagen alpha-5(IV) chain", "aln": "MQVRGVCLAAGWFLLALCLWGQPAEAAACHGCSSGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSPLPGPKGNQGYPGPPGIQGPPGPKGISGPSGPPGPPGLMGPPGPPGPPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDIEFQ---KGDQGVPGDRGPPGPPGIPGPPGPPGGVKGEKGEPGEAGKRGKPGKDGETGQPGIPGLPGDPGYPGEPGRDGEKGQKGDIGPPGPPGLVIPAPGTGVTMGEKGNIGLPGLPGEKGERGFPGIQGPPGFPGPPGTAVVGPPGPPGYPGERGQKGDEGPPGICIPGSPGLDGQPGAPGLPGPPGPPGPQLPSRDEICKAGPPGPPGPPGDKGLQGERGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGIPGEKGDKGQAGITGPKGLPGIPGPPGAPGFPGSKGDPGDVLTLPGMKGDKGELGFPGAPGLPGLPGSPGKDGLPGLPGPKGEPGGITFKGERGPPGSPGLPGLPGNMGPTGPVGFGPPGPIGEKGIQGVAGNPGQPGLPGPKGDPGQTITQPGKPGLPGSPGRDGEVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGPPGPPGPKGFPGIPGPPGAPGAPGRMGPDGPPGPPGFPGPKGEPGFGLPGPPGPPGFPGFKGTPGPKGDRGFPGPSGPPGRTGLDGLPGPKGDVGPNGQPGPVGPPGLPGIGLQGPPGPPGTPGPIGQPGLHGIPGEKGDPGPPGFDVPGLPGERGSPGLPGAPGLIGPPGSPGVPGKAGVPGFPGVKGEMGMMGPPGPPGPLGIPGRSGAPGLKGDDGMQGQPGLPGPAGEKGGKGEPGLPGPPGPMHPDFLGSKGEKGEPGLPGIPGLSGPKGYQGLPGDPGQPGLSGQPGSPGLPGPKGNPGLPGPPGLTGPPGPKGNIGDMGFPGPQGVDGPPGPPGFPGQPGSPGLPGQKGSKGEPGVSGIGLPGLPGPKGEPGLPGYPGNPGIKGSVGETGLPGLPGNPGAKGQPGLPGFPGTPGLPGPKGMNGPPGNPGFPGEPGPVGAGGRPGPPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGIPGPPGLPGLSGQKGDGGSPGLPGNPGLPGSKGEPGFQGFPGMPGPPGPPGSPGQALEGPKGNPGPQGPPGRPGPPGFQGPPGTEGPRGPPGNGGIKGERGNPGPPGQPGLPGLKGDQGPPGLPGNPGRPGLNGMKGDPGLPGVPGFPGMKGPIGVPGSTGPDGEPGLTGPPGPPGLPGPSGQSIVIKGDPGPPGIPGQPGLKGLPGLPGPQGLPGPIGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGARGLDGPPGPDGLQGPPGPPGTTSVAHGFLITRHSQTTEAPQCPRGTVHIYEGFSLLYVQGNKRAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMNMEPLKGQSIQPFISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVDMSDMFNKPQSETLKAGDLRTRISRCQVCMKRT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29400-1", "uniprot_id": "CO4A5_HUMAN", "id": "P29400-1", "name": "Collagen alpha-5(IV) chain", "aln": "MKLRGVSLAAGLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQ---KGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPP------GLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQGNKRAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMQPLKGQSIQPFISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDMFSKPQSETLKAGDLRTRISRCQVCMKRT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58FXL4-1", "uniprot_id": "A0AC58FXL4_DANRE", "id": "A0AC58FXL4-1", "name": "", "aln": "MNLKSLG-AVLLLVLTLSAGVEKSESAACHGCGTGSKCDCSSVKGVKGDRGLPGLKGQPGVPGFPGPEGPMGPRGEKGDDGPQGSIGPKGIRGPPGLPGFSGTPGIPGLPGQDGAPGPRGIPGCNGTKGERGFPGNPGRSGLDGQPGPPGLIGQKGEPGEVIDINRISENGLPGFNGFTGRRGDPGPPGLQGPIGPPGPKGFEGRPGPPGPPGPKGNMGLNFQGPKGEKGDRGLKGPPGPPGQVGEVSGSPDTVIQQGEKGDRGIPGDTGFPGPP---GPPGPQGGQKGEKGEPGEAGKRGKPGKDGEPGLLGYPGDKGDQGPPGLPGRDGFRGEKGDQGPPGPPSYRGDQFTGVGGIGPKGDRGDPGPSGIKGDRGLPGIQGPPGPQGPPGIGGPGPPGSQGLPGERGEKGDEGQPGISLPGPPGRPGPTGPQGIQGPPGPPGPFN--SDVECNRGLPGPPGLQGERGFTGDSGQKGQKGETCVNCFSNGNP-VPGPQGFPGPPGSPGAPGASGSKGDRGYPGGPGLMGPPGIPGPQGSPGLPGEKGDPGDTLSVLGVKGDKGDTGFPGSPGLPGLEGRPGRDGVPGPPGLRGPPG-LGLKGTQGPNGEPGLPGPPGDRGLPGSPGFGPQGPSGEKGIQGVSGRPGAPGLPGQKGEPGMTVPEVGERGPPGQDGDPGSQGRPGDSGPPGQPGFPGLPGSKGEPGLPGIGLPGPPGAKGFPGIAGSPGGPGIPGRPGLDGLPGQPGLPGSKGDPGYGLPGPPGPTGSPGIKGGPGPKGDSGFPGSPGQPGRPGLDGAPGPKGDAGFPGGPGPRGPPGAPAFGLQGPPGPPGAPGSIGSPGVPGANGEKGDRGPPGLSTPGFQGDRGISGLPGPPGPVGPPGVPGRPGQDGLPGLPGSKGEMGSMGPPGSKGNPGNPGAPGFPGPKGDDGVPGQSGNPGFPGLKGDKGETGIQGPPG-ITTSTSVLKGQKGESGVPGFSGPPGPKGITGISGDPGLPGQDGRPGLPGPPGPKGDAGLPGIPGSPGATGLKGAMGEMGLPGVPGVKGNSGQPGQPGQPGSPGGPGFPGPKGEAGVPGYGLPGNPGPKGEPGTPGFPGPAGLKGQPGFPGPQGLTGSPGPKGDPGLPGFQGAPGNPGPKGLDGAPGPAGLNGAPGRPGDPGRSGLPGIPGDKGLAGRDGIPGPAGQKGEPGAPGLGGPGLPGQPGLKGAKGDPGFPGPAGSAGFPGPKGDAGFPGLPGQIGSVGPPGPPGLPLQGPKGIQGPPGPPGRAGPPGLEGPR------GPPGSGGVKGEKGLPGVPGTPGEAGQKGDYGSPGFPGSPGSPGPNGLKGDPGPQGVPGFPGSKGVSGPPGISGLPGARGDPGDKGPPGPPGYAAEPIVLKGERGPPGPPGNPGGRGQAGPIGLQGLPGSPGSSGDPGPMGPPGFNGPPGRKGDTGPAGQPGQRGYPGPPGPDGAPGPPGITGTLSGAHGFLITRHSQTIEVPSCPDGTSPIYEGYSLLYVQGNERAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPQPMPMTMAPITGENIKPYISRCSVCEAPAMVIAVHSQTIQLPACPENWDTLWIGYSFMMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYGNSYSFWLATVDVNEMFRKPQSETLKAGNLRTRVSRCVVCMKRT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: .: *. ::*:*. : .*:***:**..*******.:** **:**:***:*:**:********* ****:***** *. **************.****:**:**:******:****************.** .**:* *****: * *****.:* . :* *: * .* :* *** *: ** ***** *: * ***** *******************::**:********:.* . . * :* ***:*:*** * **** ***** ** ****** **.*********** * * ** ** * ** ***.* :*:*** ******. :* **: * ** .* **:**:******** **** . ****. * *****:***** ***.:**.** * .*. *: *****.** * *: * ***** *::*: *: * **:**:**.**:..* . ** *:** **.**: * .*.**::* .* .* * *****. *:**:**.**:*** *:. *:**:**: * **:****** * **:**:** ** :* ** : :** :** *.***** **: * *. **** ** ********:*.** **:** **:** *:.: *: * **. * *. * ***.* *****:**:********:**** *****.******.*.** ** *** * :* ** **:**.**:**:.*******.* **:** ***** *:**..* **:.**** ******.* * *** **** *.:*:******** **.**.**: * ***** ****:..** *:** .*:**.** :**** ** **: * .*:** ***** *****. * * ** .* ** *****: **.* ** * **.***.*: **** : .. **:**:.*:**:.* .**** *:.**** ** .*:** ** ***** .**** ** *..* ** :*:**:** **.* .* .* ******** ** * **:.*:.. **** ******** **:** .*:**. * .* **.*.**.**:****** *:** *****:.*.** .*: * ** * *:.* ** **:** .*:************** **:* ** ** ***.* *** * ** .*..*:**.**:.** *:** *. ****.** .*:**** ** *****.* ** :** * **.**:***:* ** ** ** .* *** *.**: *.** ** **:***** ******* ** * ** :* * * * **** ** :.:.*::**: **** **:** :* .* * *****. *..**** * ***:*. *****.* .**** ** ******* **** .** * ************ :.*.** ** :*:*:********:**********************************************:****.* *:.*:.*:*:****:******:**********:* **:.**:*************************************************.***********:.:** **********:****:*** ******", "identical_positions": 1080, "similar_positions": 286, "identity": "63.75%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2286", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BQB6-1", "uniprot_id": "VKOR1_HUMAN", "id": "Q9BQB6-1", "name": "Vitamin K epoxide reductase complex subunit 1", "aln": "MGSTWGS--PGW---VRLALCLTGLVLSLYALHVKAARARDRDYRALCDVGTAISCSRVFSSRWGRGFGLVEHVLGQDSILNQSNSIFGCIFYTLQLLLGCLRTRWASVLMLLSSLVSLAGSVYLAWILFFVLYDFCIVCITTYAINVSLMWLSFRKVQEPQGKAKRH---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CRC0-1", "uniprot_id": "VKOR1_MOUSE", "id": "Q9CRC0-1", "name": "Vitamin K epoxide reductase complex subunit 1", "aln": "MGTTWRS--PGL---VRLALCLAGLALSLYALHVKAARARDENYRALCDVGTAISCSRVFSSRWGRGFGLVEHMLGADSVLNQSNSIFGCLFYTLQLLLGCLRGRWASILLVLSSLVSVAGSVYLAWILFFVLYDFCIVCITTYAINVGLMLLSFQKV--PEHKTKKH---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F6X2-1", "uniprot_id": "E7F6X2_DANRE", "id": "E7F6X2-1", "name": "vitamin-K-epoxide reductase (warfarin-sensitive)", "aln": "MSSHSASGVPKWEFRVRLILCILGLVLSVYALHVELSRENNPEYRAMCDLGNSVSCSKVFTSRWGRGFGLVQIFTSKDSVLNQPNSVLGIIFYTLQLGLGQTVSSRAGFFLVMSSWVSVAGSVYLASILAFVLGDFCVVCVSTYIINFALLYTNLKRRTGLEARLKKGKSQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: * * *** **: **.**:*****: :* .: :***:**:*.::***:**:**********: . . **:***.**::* :****** ** *..::::** **:******* ** *** ***:**::** **..*: .::: : : *: ", "identical_positions": 83, "similar_positions": 45, "identity": "48.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2291", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K9D9-1", "uniprot_id": "A0A0G2K9D9_RAT", "id": "A0A0G2K9D9-1", "name": "", "aln": "----------------------MNPEEEKANIISEDFTGDGV-------DTEAGRQ------KKNLKVQKKQKKKRPPTTPPEEMVSDKFQDGGQQEMVEEE-----PETNLLSLPARRGPRSLPPIPSASR------TGFVEFSMRERMREKLQAARSKAESALLRDVPTPRPRRLRSP-RERETETEFGTEPSTEVQGTQQEDDTRSYSRIKLRDSVQKIKSKPQPPPGFPSAEEAYNFFTFNFDPEPEEPEEKTPVKGGDGAHQEEQEG---------EEG-THTQEREKKMEEEELLDGKDAEDFLLG-------LDPTAHDFVAVRAAEYKSAHLQLQKEKEILFTPSRLTVPTYKKLPENIQPRFLEDEGLYTGARPEVARTNENIMENRLLIQEPERKWFGDDGRILALPSPIKPFPSRPSLSTQERSPKAELETLYKKAEKYVHSRQHMIASGEPPGNFQLDIDISGLIFTHHPCFSREHVLASKLAQLYDQFLARQQRNKTKFLTDKLQALRRAVETSLNPEKPHQSLDTTQKTINEYKSEIRQTRKLRDAEQEKDRTLLKTIIKVWKEMKSLREFQRFTNTPLKLVLRKERVDQKLDEEVYEAEIQAEIRELLEEHMEEYALKMEEYRASRQHWKAWRKAQKAKKKKKKQTAEEHPEEEEAEEPFPEEEVKKPIPPEPTDPADIEQQVRERVAHSRRRPGEPALIPELSLAGNVTPNDQCPRVEVSRREDVRRRSVYLKVVFNNKEVSRTVSRPLGADFRVHFGQIFNLQIFN-WPESLMLQVYET-IGHSGATLLAEVFLPIPETTLVTGRAPIEEVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMTSGKVSHSVAWAVGENGIPLIPPLSQQNIGFRSALKRADAISSIGTSGLTDMKKLAKWAAESKLDPNDPNHAPLMQLISVATSGESYVPDFFRLEQLQQEFNFVSEEELNRSKRFRLLQLRNQE-VPEFRNYKQIPVYDREIMEK-VFQDYEKRLRDRNVIETKDHLDTHRATVAKYLQQVRESVVNR--FLTAKHHFLLTDLVVEEEVPNISSEGSGILGLSLFKLAEQKRPLRPRRKGRKKVTAQNLSDGDIKLLVNIIRAYDIPVRKPVVSKFQQPSRSSRTFSEKQTASPSTHSPLHNDDYPLSQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPFRAPNGDYSTASLQSVKDDVYINIFDEVLYDILEDDRERGSGIHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPPVLLGYSK-ERNIIMERAFDSARSLSEGSYITLFITIEPQLVPGEPIREKMSGMLKKFDTQEDEKLLQATEKFQAECALKFPQRQCLTTVTDMNGKTVFITRYLKPLNPPQELLNVYPNNPQATAELVARYVSLIPFLPDSVSFAGVCDLWSTSDQFLDLLAGDEEEHAVLLCNYFLFLGKKAWLVMGNAIPEGPTAYVLTWE--KNYYLIWNPCSGHCYGQFDAFCPLKSVGCLIGPDNIWFNIQHHDSPLRINFDVTKPKLWKSFFSRSLPYPGLSSVQPEELIYQHTDKATAAELQDRIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLE----RSQGEDIEDDHRAELLKQLGDYRFSGFPLHMPYSEVKPLIEAVYSTGVHNIDLPNVEFALAVYIHPYPKNVLSVWIYVASLVRNR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CFW7-1", "uniprot_id": "C2D2A_MOUSE", "id": "Q8CFW7-1", "name": "Coiled-coil and C2 domain-containing protein 2A", "aln": "----------------------MNTNDEKMKIISEDFTGDGV-------DTEAGRR------KKNSKVRRQQRKKKPPASPPEEMVSDKFQDGGQQEVVEEE-----PETNLLSLTARRGPRSLPPIPSASR------TGFAEFSMRERMREKLQAARSKAESALLRDVPTPRPRRLRSPSREKETETEFGTEPSTEVQDTQKEDDTKSYSRIKFRDSVRKIKSKPQLPPGFPSAEEAYNFFTFNFDPEPEESEEKSPVKGGERAHHEDQEG---------EEG-TQAQERAKKTEEEELLNGKDAEDFLLG-------LDPTAHDFVAVRAAEYKSARIQLQKEKEILFTPSRLTVPTYKKLPENIQPRFLEDEGLYIGARPEVARTNENIMENRLLIQEPGSKWFGDDGRILALPSPIKPFPSRPSLTTREQSPKAGLETLYKKAEKYVHSRQHMIGSGDPPGNFQLDIDISGLIFTHHPCFSREHVLASKLAQLYDQYLARQQRNKTKFLTDKLQALRKAVQTSLNPEKPHQSLDTTQKTINEYKSEIRQTRKLRDAEQEKDRTLLKTIIKVWKEMKSLREFQRFTNTPLKLVLRKEKVDPKLDEDAYEAEIQAEIHELLEEHMEEYATKMEEYRTSHQQWKAWRKAQRAKKKKKKQTTEEHLEEEEAEESFPEEEVTKPIPPEPTDPAVIEQQVRERAAHSRRRPGEPTLIPELSLAGNVTPNDQCPRVEVSRREDVRRRSVYLKVVFNSKEVSRTVSRPLGADFRVHFGQIFNLQIFN-WPESLMLQVYET-IGHSGTTLLAEVFLPIPETTLVTGRAPIEEVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMTSGKVSHSVAWAVGENGIPLIPPLSQQNIGFRSALRRADAISSIGTSGLTDMKKLAKWAAESKLDPNDPNHAPLMQLISVATSGESYVPDFFRLEQLQQEFNFVSEEELNRSKRFRLLHLRSQE-VPEFRNYKQIPAYDREIMEK-VFQDYEKRLRDRNVIETKDHLDMHRATVAKYLQQVREAVVNR--FLTAKHHFLLTDLVVEEEVPNISSEGSGILGLSLFKLAEQKRPLRPRRKGRKKVTAQNLSDGDIKLLVNIIRAYDIPVRKPVVSKFQQPSRSSRTFSEKQTASPSTHSPLHNADYPLGQVLVRPFVEVSFQRTICHTTTAEGPNPSWNEELELPFRAPNGDYSTASLQSVKDDVYINIFDEVLYDILEDDRERGSGIHTRIERHWLGCVKIPFSTIYFQARIDGTFKIDIPPVLLGYSK-ERNIIMERAFDSARSLSEGSYITLFITIEPQLVPGEPMREKMSDMLKKFDTQEDEKLLQATEKFQAECALKFPQRQCLTTVTDMTGKTVFITRYLKPLNPPQELLHVYPNNPQATAELVARYVSLIPFLPDSVSFAGVCDLWSTSDQFLDLLAGDEEEHAVLLCNYFLFLGKKAWLVMGSAIPEGPTAYVLTWE--KNYYLIWNPCSGHCYGQFDAFCPLKSVGCLIGPDNIWFNIQHHDSPLRINFDVTKPKLWKSFFSRSLPYPGLSSVQPEELIYQHTDKAVAAELQDRIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLE----RSQGEDIEDDHRAELLKQLGDYRFSGFPLHMPYSEVKPLVEAVYSTGVHNIDLPNVEFALAVYIHPYPKNVLSVWIYVASLVRNR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2K1-4", "uniprot_id": "C2D2A_HUMAN", "id": "Q9P2K1-4", "name": "Coiled-coil and C2 domain-containing protein 2A", "aln": "----------------------MNPREEKVKIITEEFIENDE-------DADMGRQ------NKNSKVRRQPRKKQPPTAVPKEMVSEKSHLGNPQEPVQEE-----PKTRLLSMTVRRGPRSLPPIPSTSR------TGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRRLRSP-SKKELETEFGTEPGKEVERTQQEVDSQSYSRVKFHDSARKIKPKPQVPPGFPSAEEAYNFFTFNFDPEPEGSEEKPKARHRAGTNQEEEEG---------EEEEPPAQGGGKEMDEEELLNGDDAEDFLLG-------LDHVADDFVAVRPADYESIHDRLQMEREMLFIPSRQTVPTYKKLPENVQPRFLEDEGLYTGVRPEVARTNQNIMENRLLMQDPERRWFGDDGRILALPNPIKPFPSRPPVLTQEQSIKAELETLYKKAVKYVHSSQHVIRSGDPPGNFQLDIDISGLIFTHHPCFSREHVLAAKLAQLYDQYLARHQRNKAKFLTDKLQALRNAVQTGLDPEKPHQSLDTIQKTINEYKSEIRQTRKFRDAEQEKDRTLLKTIIKVWKEMKSLREFQRFTNTPLKLVLRKEKADQKADEEAYEAEIQAEISELLEEHTEEYAQKMEEYRTSLQQWKAWRKVQRAKKKKRKQAAEEHPGDE-IAEPYPEEDLVKPSPPEPTDRAVIEQEVRERAAQSRRRPWEPTLVPELSLAGSVTPNDQCPRAEVSRREDVKKRSVYLKVLFNNKEVSRTVSRPLGADFRVHFGQIFNLQIVN-WPESLTLQVYET-VGHSSPTLLAEVFLPIPETTVVTGRAPTEEVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMTSGKVSHSVAWAIGENGIPLIPPLSQQNIGFRSALKKADAISSIGTSGLTDMKKLAKWAAESKLDPNDPNNAPLMQLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLHLRSQE-VPEFRNYKQVPVYDREIMEK-VFQDYEKRLRDRNVIETKEHIDTHRAIVAKYLQQVRESVINR--FLIAKQYFLLADMIVEEEVPNIS-----ILGLSLFKLAEQKRPLRPRRKGRKKVTAQNLSDGDIKLLVNIVRAYDIPVRKPAVSKFQQPSRSSRMFSEKHAASPSTYSPTHNADYPLGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELELPFRAPNGDYSTASLQSVKDVVFINIFDEVLHDVLEDDRERGSGIHTRIERHWLGCVKMPFSTIYFQARIDGTFKIDIPPVLLGYSK-ERNMILERGFDSVRSLSEGSYITLFITIEPQLVPGESIREK-------FESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVYPNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSDQFLDLLAGDEEEHAVLLCNYFLSLGKKAWLLMGNAIPEGPTAYVLTWE--QGRYLIWNPCSGHFYGQFDTFCPLKNVGCLIGPDNIWFNIQRYESPLRINFDVTRPKLWKSFFSRSLPYPGLSSVQPEELIYQRSDKAAAAELQDRIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLE----KSQGEDVEDDHRAELLKQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWIYVASLIRNR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58INI6-1", "uniprot_id": "A0AC58INI6_DANRE", "id": "A0AC58INI6-1", "name": "", "aln": "MSSPGDVREKIKKKRRELQESLGKVRDDKQALVPSDWDVSKENEHTAVEDMAGGKEDPGETLRHSLMARRMKKKKKASYQFDCSLFLQLLKESAVECIADDEELTAVPDTRGADGQHARTPTELSPRDASPHTVMRPGSSQSEKTMRQRMTEKLRAAKSKAASLLEQESSIEPVSRLQSL-QDRDTVTRFDRDMDPDLR---ADEDSSFAARLKFRDAARRAVKDKQAEAGLPTAEEAYNFFTFNFDPEPEQQRQKKKRRSRRREAEEEEEGDSEGEVEGEDEEGEEVGELERQNEGEEESEARDEDDPLVGDEEDLFIIDQSAQDFLEVRRAEYVDYSRRLQRERDTLFVPSMRPVPASSKLAENTRPRFLEEEGLYVGERPHVCLTNLNILENRILKQAEGRRWFGDDGRIVALPDPIKESSSRPPLFHLEDQLDPALQTVYRKALKSKHVNLYIAGMGDPQADYQLDVDVSGLIFSHHPLFSREHVLGARLAQLYDQHLTRLHKNLTQLLTDKLNSLRNTIHNMLELHRGEALSQVSQQRIAEYKQEVRHTRQLRDVEQEKDRALLKNIIRLWKELKALRDFQRFTNTPYKLFIRREKVERLQDEQEFESDIMAEVSELQAETEEEYQRKMNEYRRLHEEWKSWKRKQKALKKKQKKKRQEEEEEDEVSEGELGEEPEKPNPPEKPDTSILEEQVREKAARIRRNPGEPVLIPELTVSGSITANEQCPRAEFARREDVAKRSLFVKVLYNDKEVSRTDSRTLNMDFRVHFGQIFNLKIVN-WPESIKLQVFES-VGSS-STQLTEVCVPVPESSVLTGSAPSEEMEFSSNQRVTFNHEGVGSGVPFSFEADGTNPQTLLTSGKLSCCVSWAVGEDDVPLAPPSAQPGVAMHSGLRQMDAIACIGASGLNDMKKLGKWAAESRLDPNDPSNASIMQLLSVVSGGDMAVPEYFRLEQLQEEFNFLSEEELQRSRRYRLLRLRSQE-VQEFRHFKCVPSTDREISEK-VFQDYENRLKEGEIIDTKEHIDAHRALVAKYLQRVRESVINR--FLIAKHHFILSDVISEDEVPSIGGPGAGVLGWNLFKLAEPKRPLKPRRKERKKVTAQNLSEGDIKLLVNIIRGYDIPVRRPYTGKAPVSAKSGRSFTETFTA-PASQTGQQGSEWPFAQPLIRPFVEVSFQRSVLQTSTAEGPNPCWNEEIVLPFSAPNGDYSSTSLQSVRDEVFINVFDELLYDVVEDERERGNTIHTRIERHWLGSINIPFSTIYLQSRIDGTFKVCTPPVLLGYSK-ERSLGSEGGYDAVRSPSEGTFLSLFITIEPQLVPGDTVREKMK--EVKFDSQEVERVLLASEVFEKEASRRFSDRPCITTVIDINGKTVFVTRFIRPLNPPQELLDASPNGTQDSTELVARYVSLIPSLPDSVSFAGVCDLWSTCDQFLTLLAGDEEEHAVLLCNYFLSMGKRAWLIIGSAIPEGPTAYVLTYE--QSRYVIWNASTSQHYGQYDVFCPLQTIGCLINADNVWFNIQPYAAPVRMSFDISKPNLWKPFFSRAFPDPGLSSVQPDALVYRRTDRTAAVELQDRIEKVLREKLMEWRPRHPTRWNRYCISTLRQFLPKLE----LSGGREVAEEHRLELQSLLGEYRISGFPLHLPFSELRPIIEAVHSTGVHKVESPNVEFALAVYVHPYPSNVLSVWVYIASLVSAY-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZAV1-1", "uniprot_id": "C2D2A_DROME", "id": "A1ZAV1-1", "name": "Coiled-coil and C2 domain-containing protein 2A", "aln": "--------------------------------------------------------------MEAALSRKTAKKKRKTHTTRG------------------------------------------------------------YRKREQEVQKLIRATEGRISGPEHDMEALSLQFFHGFEGEMQQENDFAVEDCQESD----------------EDSGGELAEEPTDSP-------SQTFIHIDLHDPPLAWGQLFKQRHYYDESLLYRPS----------------NTLHFQLHLSDLSELKDSQIRMLN------------------------------RYQEQSKSKSGKLGSDLIGQLSGQKPASFLMGKHLYRS-------VCHRRFQSVFFPPMP--------------PSELKGLPSRR----------------------------------------CLKLCLKQLRFSLHPQLLEEHRLAQQLEDLFDVYSQQRKQRICRKLREELEIARQVALKLLASAGQDQTAEVKR-----QLKLTRQLRQRYYAESAAQRNLLQRLLKEWAKLKELRRQQRFQCTRFQLGLR------VVHPPDLEASYCAWKESFETDLAEVYREHLELFYTRLRLWTDQKSHSRTATGHSK-------------------------PPRKPQFDRIMASLRKEYDKTFKDPEEPYVEVFRLHADEATARLSIPGGDQLP----KARNYFLKIFLDGQFVGQSRTYRLEPDLQISINECIGVLLERSLPENLNIWLYEKSTLTPKSRRLAQISTPLVLSSKDD--AVQEKLSFQALSSTQLAGD-VYLYYEYRSTEGWGSALHLDDVQRLPDALRQTLLPQSLPALPQASKELVTPR------------------------------------------------PPSGRIKKSQLPSLIFAEQQLQFCGLDVLLDNRRFQLLHSRHQQRNLHTKQLRFVPALEQEISEEEPLPDGRGTVQLLEPGTYWNPIDLHKHRGRKFLQLLYEVIASQSARRAKALQTPLPLLLLAEDSDRSSGTGWTALWRAFCSVFQGQRNSLPREPS---------GWSGHQSAPDLFKSFCVSLHVVRATGVPVRSRHILNLNERRSSAGGDMSTSLFVTQTLMYSNVRPFVTLSYGQRLCRSRTAEGSNPTWNEQLQLQIQSQFG--------DLRDDLKISLFDELIEQQYSDEAS---DVYQRVQCNWLGEFRVPINSLLASRTFEGCIELAMPKVLVGYKRPLIDSVTNMPTDQYPEFKEAVHLWFYLSIE----PGGGDLAPLHSCALACAEKPELQQYLDERRLELQQLLPQPQRYVEPLVCTAQGKRVCLTRLMDPVPLPPAAVPSGEN----PLEICIRYVSLLSHLRSYDPCQGFRGVWLDNQSLLDSTWCSVKDLGVLLCNYMLSLGLECWLILGVSCPHGECSFVLFRQPETAELFLVSPATGKRYQLQDVHCPLRRIYCVVGKQNIYFNIQTETRVSMTHFNLQDGACWFPLFRRRVPAP-QSGVQKLDYAYKRS--YELSQLQKHIERKIMKKISAWRTTRKTIWNRAFQPRLHKILCDMEDLSTFSRGRYDEPIFSEQLEREFPNYRLYGFTLNFAYTNLAAISERIRTSCIHYNHDASVEFCVAVHLHAHANDVLSVWLFLLSMVPLVE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: :**: . * : :** * . * :: ::. . : . * : : .*: . . . : .*: :::. * : : . . : . .: : * : ::. : :.: .. :*. : . ** : ** . . . ::. :: *. :* .** *.: :. * *: ** : .** *. :* :*:* . : ::. : * ::*: *.. . * . :. : . *: *: .*. :* **: ::: * ::* ** *** * :* :* . *:. * .: : * * ::: : . *. : .:: . : * **. .: : .:*:. : : * ** : :.. *.. . * : *. ::*:. :.: *.:: : * *::: :.: :.: : . **.: : ::*. . . *::: *: :: * *::.*.: . . : : * : . . * ::. .: :: :.:* * :: : : ..* .: * :::::* . : * .:*::**: * *: . :: : :* ::** *: : * . :: : : :* *: *:** : * : .: *. :: :: . * : .: : :* **. . .. : ::.:.: :.:: . :: :.* :: . : .: :**** :*: : : :: ****.** ***:: * : : * .::* : *.:***:: : .*: . :: *:: :*** ..:*:.:: . ::* ::: * **:**.: . : * . .*. .: ::::** ** : : . :: : .:* . * ** * :** : *: * : * . *: *****:. * . . *. .:* :.:* . :: .******:* :* ..**::* : *.* ::** : .: ...:.: * *..***: : *::. :*::**** *:: * .:* * .* * *.** *::: :**.:**: : :*: **. : * *** . *:::* :* * *. . :* : :**: **.*::.:::: .: : : :: :* . ..***.:**::*.:..:*****::: *:: ", "identical_positions": 239, "similar_positions": 456, "identity": "13.98%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2299", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q00610-1", "uniprot_id": "CLH1_HUMAN", "id": "Q00610-1", "name": "Clathrin heavy chain 1", "aln": "MAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSNPIRRPISADSAIMNPASKVIALKAG-KTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVALVTDNAVYHWSMEG---ESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAASFAQFKMEGN-AEESTLFCFAVRGQAG--GKLHIIEVGTPPTGNQPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISGETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGAEELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSP-LLQYFGILLDQGQLNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVDPTLALSVYLRANVPNKVIQCFAETGQVQKIVLYAKKVGYTPDWIFLLRNVMRISPDQGQQFAQMLVQDEE--PLADITQIVDVFMEYNLIQQCTAFLLDALKNNRPSEGPLQTRLLEMNLMHAPQVADAILGNQMFTHYDRAHIAQLCEKAGLLQRALEHFTDLYDIKRAVVHTHLLNPEWLVNYFGSLSVEDSLECLRAMLSANIRQNLQICVQVASKYHEQLSTQSLIELFESFKSFEGLFYFLGSIVNFSQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKEAKLTDQLPLIIVCDRFDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKNLILVVRGQFSTDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNPERFLRENPYYDSRVVGKYCEKRDPHLACVAYERGQCDLELINVCNENSLFKSLSRYLVRRKDPELWGSVLLESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFAIFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADDPSSYMEVVQAANTSGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQVGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFACVDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTELAILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAIITMMNHPTDAWKEGQFKDIITKVANVELYYRAIQFYLEFKPLLLNDLLMVLSPRLDHTRAVNYFSKVKQLPLVKPYLRSVQNHNNKSVNESLNNLFITEEDYQALRTSIDAYDNFDNISLAQRLEKHELIEFRRIAAYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELAEELLQWFLQEEKRECFGACLFTCYDLLRPDVVLETAWRHNIMDFAMPYFIQVMKEYLTKVDKLDASESLRKEEEQATETQPIVYGQPQLMLTAGPSVAVPPQAPFGYGYTAPP-----YGQPQPGFGYSM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11442-1", "uniprot_id": "CLH1_RAT", "id": "P11442-1", "name": "Clathrin heavy chain 1", "aln": "MAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSNPIRRPISADSAIMNPASKVIALKAG-KTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVALVTDNAVYHWSMEG---ESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAASFAQFKMEGN-AEESTLFCFAVRGQAG--GKLHIIEVGTPPTGNQPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISGETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGAEELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSP-LLQYFGILLDQGQLNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVDPTLALSVYLRANVPNKVIQCFAETGQVQKIVLYAKKVGYTPDWIFLLRNVMRISPDQGQQFAQMLVQDEE--PLADITQIVDVFMEYNLIQQCTAFLLDALKNNRPSEGPLQTRLLEMNLMHAPQVADAILGNQMFTHYDRAHIAQLCEKAGLLQRALEHFTDLYDIKRAVVHTHLLNPEWLVNYFGSLSVEDSLECLRAMLSANIRQNLQIWVQVASKYHEQLSTQSLIELFESFKSFEGLFYFLGSIVNFSQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKEAKLTDQLPLIIVCDRFDFVHDLVLYLYRNSLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKNLILVVRGQFSTDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNPERFLRENPYYDSRVVGKYCEKRDPHLACVAYERGQCDLELINVCNENSLFKSLSRYLVRRKDPELWGSVLLESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFAIFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADDPSSYMEVVQAANTSGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQVGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFACVDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTELAILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAIITMMNHPTDAWKEGQFKDIITKVANVELYYKAIQFYLEFKPLLLNDLLMVLSPRLAHTRAVNYFSKVKQLPLVKPYLRSVQNHNNKSVNESLNNLFITEEDYQALRTSIDAYDNFDNISLAQRLEKHELIEFRRIAAYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELAEELLQWFLQEEKRECFGACLFTCYDLLRPDVVLETAWRHNIMDFAMPYFIQVMKEYLTKVDKLDASESLRKEEEQATETQPIVYGQPQLMLTAGPSVAVPPQAPFGYGYTAPP-----YGQPQPGFGYSM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q68FD5-1", "uniprot_id": "CLH1_MOUSE", "id": "Q68FD5-1", "name": "Clathrin heavy chain 1", "aln": "MAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSNPIRRPISADSAIMNPASKVIALKAG-KTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVALVTDNAVYHWSMEG---ESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAASFAQFKMEGN-AEESTLFCFAVRGQAG--GKLHIIEVGTPPTGNQPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISGETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGAEELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSP-LLQYFGILLDQGQLNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVDPTLALSVYLRANVPNKVIQCFAETGQVQKIVLYAKKVGYTPDWIFLLRNVMRISPDQGQQFAQMLVQDEE--PLADITQIVDVFMEYNLIQQCTAFLLDALKNNRPSEGPLQTRLLEMNLMHAPQVADAILGNQMFTHYDRAHIAQLCEKAGLLQRALEHFTDLYDIKRAVVHTHLLNPEWLVNYFGSLSVEDSLECLRAMLSANIRQNLQICVQVASKYHEQLSTQSLIELFESFKSFEGLFYFLGSIVNFSQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKEAKLTDQLPLIIVCDRFDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKNLILVVRGQFSTDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNPERFLRENPYYDSRVVGKYCEKRDPHLACVAYERGQCDLELINVCNENSLFKSLSRYLVRRKDPELWGSVLLESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFAIFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADDPSSYMEVVQAANASGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQVGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFACVDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTELAILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAIITMMNHPTDAWKEGQFKDIITKVANVELYYKAIQFYLEFKPLLLNDLLMVLSPRLDHTRAVNYFSKVKQLPLVKPYLRSVQNHNNKSVNESLNNLFITEEDYQALRTSIDAYDNFDNISLAQRLEKHELIEFRRIAAYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELAEELLQWFLQEEKRECFGACLFTCYDLLRPDVVLETAWRHNIMDFAMPYFIQVMKEYLTKVDKLDASESLRKEEEQATETQPIVYGQPQLMLTAGPSVAVPPQAPFGYGYTAPP-----YGQPQPGFGYSM-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1R966-1", "uniprot_id": "F1R966_DANRE", "id": "F1R966-1", "name": "Clathrin heavy chain", "aln": "MAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICVREKVGEQAQVVIIDMADPNTPIRRPISADSAIMNPASKVIALKAA-KTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVALVTDNAVYHWSMEG---DSQPVKVFDRHSSLAGCQIINYRTDAKQKWLLLIGISAQQNRVVGAMQLYSVDRKVSQPIEGHAAGFGQFKMEGN-TEESTLFCFAVRGQAG--GKLHIIEVGTPPTGNQQFPKKAVDVFFPPEAQNDFPVAMQISSKHDVVYLITKYGYIHLYDLETGTCIYMNRISGETIFVTAPHDATAGIIGVNRKGQVLSVCVEEENIIQYITNVLQNPDLALRMAVRNNLAGAEELFGRKFNNLFAGGNFAEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSP-LLQYFGILLDQGQLNKFESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVDPTLALSVYLRANVPNKVIQCFAETGQFPKIVLYAKKVGYTPDWIFLLRNVMRISPDQGLQFAQMLVQDEE--PLADITQIVDVFMEYNLVQQCTSFLLDALKNNRPSEGPLQTRLLEMNLMHAPQVADAILGNQMFTNYDRAHIAQLCEKAGLLQRALEHYTDLYDIKRAVVHTHLLNPEWLVNYFGSLSVEDSLECLRAMLSANIRQNLQICVQVASKYHEQLSTQSLTELFESFKSFEGLFYFLGSIVNFSQDPEVHFKYIQAACKTGQIKEVERICRESNCYNPERVKNFLKEAKLTDQLPLIIVCDRFDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKNLILVVRGQFSTDELVAEVEKRNRLKLLLPWLESRIHEGCEEPATHNALAKIYIDSNNNPERFLRENPYYDSRVVGKYCEKRDPHLACVAYERGTCDQELINVCNENSLFKSLSRYLVRRRDPELWASVLLETNPFRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISSELFEEAFAIFKKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGLVKESIDSYIKADDPSAYMEVVQAADQSGNWEDLVKFLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQVGDRCYDEKMYEAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFACVDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTELAILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEFDNAIITMMSHPTDAWKEGQFKDIITKVANVELYYKAIQFYLEFRPLLLNDLLIVLSPRLDHSRAVNFFSKVKQLPLVKPYLRSVQNHNNKSVNEALNNLFISEEDYQALRTSIDAYDNFDNISLAQRLEKHELIEFRRIAAYLFKGNNRWKQSVELCKKDKLYKDAMQYASESKDTELAEELLQWFLDENKKECFAACLFTCYDLLRPDVVLETSWRNNIMDFAMPYFIQVMREYLSKVDKLETSESLRKEEEQATETQPIVYGTPQLMLTAGPSVPVPPQQGYGYGYTAAPGYPPQAPQAQPGFGYGM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P29742-1", "uniprot_id": "CLH_DROME", "id": "P29742-1", "name": "Clathrin heavy chain", "aln": "MTQPLPIRFQEHLQLTNVGINANSFSFSTLTMESDKFICVREKVNDTAQVVIIDMNDATNPTRRPISADSAIMNPASKVIALKAQ-KTLQIFNIEMKSKMKAHTMNEDVVFWKWISLNTLALVTETSVFHWSMEG---DSMPQKMFDRHSSLNGCQIINYRCNASQQWLLLVGISALPSRVAGAMQLYSVERKVSQAIEGHAASFATFKIDAN-KEPTTLFCFAVRTATG--GKLHIIEVGAPPNGNQPFAKKAVDVFFPPEAQNDFPVAMQVSAKYDTIYLITKYGYIHLYDMETATCIYMNRISADTIFVTAPHEASGGIIGVNRKGQVLSVTVDEEQIIPYINTVLQNPDLALRMAVRNNLAGAEDLFVRKFNKLFTAGQYAEAAKVAALAPKAILRTPQTIQRFQQVQTPAGSTTPPLLQYFGILLDQGKLNKFESLELCRPVLLQGKKQLCEKWLKEEKLECSEELGDLVKASDLTLALSIYLRANVPNKVIQCFAETGQFQKIVLYAKKVNYTPDYVFLLRSVMRSNPEQGAGFASMLVAEEE--PLADINQIVDIFMEHSMVQQCTAFLLDALKHNRPAEGALQTRLLEMNLMSAPQVADAILGNAMFTHYDRAHIAQLCEKAGLLQRALEHYTDLYDIKRAVVHTHMLNAEWLVSFFGTLSVEDSLECLKAMLTANLRQNLQICVQIATKYHEQLTNKALIDLFEGFKSYDGLFYFLSSIVNFSQDPEVHFKYIQAACKTNQIKEVERICRESNCYNPERVKNFLKEAKLTDQLPLIIVCDRFDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVVGGLLDVDCSEDIIKNLILVVKGQFSTDELVEEVEKRNRLKLLLPWLESRVHEGCVEPATHNALAKIYIDSNNNPERYLKENQYYDSRVVGRYCEKRDPHLACVAYERGLCDRELIAVCNENSLFKSEARYLVGRRDAELWAEVLSESNPYKRQLIDQVVQTALSETQDPDDISVTVKAFMTADLPNELIELLEKIILDSSVFSDHRNLQNLLILTAIKADRTRVMDYINRLENYDAPDIANIAISNQLYEEAFAIFKKFDVNTSAIQVLIDQVNNLERANEFAERCNEPAVWSQLAKAQLQQGLVKEAIDSYIKADDPSAYVDVVDVASKVESWDDLVRYLQMARKKARESYIESELIYAYARTGRLADLEEFISGPNHADIQKIGNRCFSDGMYDAAKLLYNNVSNFARLAITLVYLKEFQGAVDSARKANSTRTWKEVCFACVDAEEFRLAQMCGLHIVVHADELEDLINYYQNRGYFDELIALLESALGLERAHMGMFTELAILYSKFKPSKMREHLELFWSRVNIPKVLRAAESAHLWSELVFLYDKYEEYDNAVLAMMAHPTEAWREGHFKDIITKVANIELYYKAIEFYLDFKPLLLNDMLLVLAPRMDHTRAVSYFSKTGYLPLVKPYLRSVQSLNNKAINEALNGLLIDEEDYQGLRNSIDGFDNFDNIALAQKLEKHELTEFRRIAAYLYKGNNRWKQSVELCKKDKLYKDAMEYAAESCKQDIAEELLGWFLERDAYDCFAACLYQCYDLLRPDVILELAWKHKIVDFAMPYLIQVLREYTTKVDKLELNEAQREKEDDSTEHKNIIQMEPQLMITAGPAMGIPPQYAQNYPPGAAT----VTAAGGRNMGYPYL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22137-1", "uniprot_id": "CLH_YEAST", "id": "P22137-1", "name": "Clathrin heavy chain", "aln": "-MSDLPIEFTELVDLMSLGISPQFLDFRSTTFESDHFVTVRETKDGTNSVAIVDLAKGNEVTRKNMGGDSAIMHPSQMVISVRANGTIVQIFNLETKSKLKSFTLDEPVIFWRWLSETTLGFVTARSILTSNVFDGNVNAKPQLLTLRHANLNNTQIINFVANKNLDWFAVVGILQENGRIAGRIQLFSKQRNISQAIDGHVAIFTNILLEGNGSTPVQVFVTGNRNATTGAGELRIIEIDHDASLPSQYQKETTDIFFPPDATNDFPIAVQVSEKYGIIYLLTKYGFIHLYELETGTNLFVNRITAESVFTAAPYNHENGIACINKKGQVLAVEISTSQIVPYILNKLSNVALALIVATRGGLPGADDLFQKQFESLLLQNDYQNAAKVAASSTS--LRNQNTINRLKNIQAPPGAISP-ILLYFSTLLDKGKLNKEETIELARPVLQQDRKQLFEKWLKEDKLECSEELGDIVKPFDTTLALACYLRAGAHAKVISCLAELQQFEKIIPYCQKVGYQPNFLVLISSLIRSSPDRASEFAVSLLQNPETASQIDIEKIADLFFSQNHIQQGTSLLLDALKGDTPDQGHLQTRVLEVNLLHAPQVADAILGNNIFSHYDKPTIASLSEKAGLYQRALENYTDIKDIKRCVVHTNALPIDWLVGYFGKLNVEQSLACLKALMDNNIQANIQTVVQVATKFSDLIGPSTLIKLFEDYNATEGLYYYLASLVNLTEDKDVVYKYIEAAAKMKQYREIERIVKDNNVYDPERVKNFLKDANLEDQLPLVIVCDRFDFVHEMILYLYKSQNLKFIETYVQQVNPSKTAQVVGALLDMDCDEAFIQSLLQSVLGQVPINELTTEVEKRNRLKILLPFLEQSLSQGIQDQAVYNALAKIYIDSNNSPEKFLKENDQYDTLDVGHYCEKRDPYLAYIAYEKGQNDDDLIRITNENSMYKYQARYLLERSDLDLWNKVLNQENIHRRQLIDSVISVGIPELTDPEPVSLTVQAFMTNGLKLELIELLEKIILEPSPFNENVALQGLLLLSAIKYEPTKVSSYIEKLDNYDADEIAPLCIEHDLKEEAFEIYDKHEMYGKALKVLIEDIMSLDRAASYADKINTPELWSQIGTAQLDGLRIPDAIESYIKAEDPSNYENVIDIAEQAGKYEELIPFLLMARKTLKEPKIDGALILAYAELNKIHEIENLLAGSNVANLDHVGDKLFENKEYKAARLCYSAVSNYSKLASTLVYLGDYQAAVDTARKASNIKVWKLVNDACIEKKEFKLAQICGLNLIVHAEELDELVERYESNGYFEELISLFEAGLGLERAHMGMFTELAILYSKYEPDKTFEHLKLFWSRINIPKVIRAVEQAHLWSELVFLYAHYDEWDNAALTLIEKSTKDLDHAYFKEVVVKVSNLEIYYKAINFYVKFHPSLLVDLLTSLTPRLDIPRTVKIFSKSDNLPLIKPFLINVLPKNNSVVNQAYHDLMIEEEDYKALQDAVDSYDKFDQLGLASRLESHKLIFFKKIGALLYRRNKKWAKSLSILKEEKLWKDAIETAAISQDPKVVEALLTYFVETGNREGFVALLYAAYNLVRIEFVLEISWMNSLEDYIKPFEISIKKEQNDSIKKIT--EELAKKSGSNEEHK---DGQPLMLMNS--AMNVQP----------------------TGF-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ***.* * ::* .:**.. :.* : *:***:*: :**. . .*.*:*: . . *: :..*****:*:. **:::* . :****:* ***:*:.*: : * **:*:* .*:.:** :: .: . :: * : **:.* . ****: : . .*: : ** .*:.* :**:* :*::**.*:**.* * : ::.* :* . * : *:*:***:. .. . : *::.*:****:* ****:*:*:* *:. ::*:****:****::**.* :::***:.:::*.:**:: ** :*:*****:* :. .:*: ** . *.* *** :*.*..*.**::** ::*: *: .:: :****** :.. **. :**.*::.: : .* :* :* **. ***:*:*** *::**.**** *.:*** ******:**********:**. * ****: ****.. ***.*:** *. **: *.:**.* *:::.*: .::* .*::. ** *: : * . ** :*.*:*:. . :** *::****** : * :* ****:**:**: *********** :*::**:. **.*.***** *****::**: ****.****: * :***.:**.*.**:** **:*:: *:: *:* **:*:*: : : .:* .***.::: :**:*:*.*:**:::* :* :***:**.* * :*:*** ::.* *:*********:*:* *****:**********:::****:.. *:** ***:****: . *:*.***:**.* .*:.*: * **.. :**. *********:***:** : :* : *.:************.**::*:** **: **:*******:** :***:* * :** : ****::* :***: * * :** .** : * .:* ***.*:...:.* **: :*:**:**** .* *********:*: * *.:: **.**:*:*** : *:* .**::*:**** :** :.*. :* **** *: *.:: .*::***:.: .*:** .:*:: * * :***:..***: : ::*:*****:*** * :*:: *. .:::*: :* ****. :*. :: ** * *. .:: ::*::: *.* *.::::*:: :.: *.**:* *. ***:.:** ***:* ::*.*** ****.. :.** * **:: :**:***:***:::***:**::*:: *:..***:***:::*:.********************::*.* ***:*****:*****:**.*.****:****** :*:*:*** :::: :.*. .. **:::.**:*:*:**:**:**:.*:* ** *:* *:**: .*:*. *** ***:**:* .* **. :*:: :.*:* ****:.*: ::*.:*:**::.**.:**.*:* *::*.* *:: *::* :*:.: *::.*:***:: *: * . .:.* ** :*:: : * * *: .*:*:* :.:** :* :.: *: *: *.: :* .:.*: * ::. . * : * :::.: :: : * .: ", "identical_positions": 742, "similar_positions": 567, "identity": "43.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-230", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1B0GWM3-1", "uniprot_id": "A0A1B0GWM3_RAT", "id": "A0A1B0GWM3-1", "name": "", "aln": "MAVALGWAPRSSPPLLVLLLLLLRMSPCWSVVAQDPPAARLSLHPPYFNLAQAAKIWATATCGERGLDVSRPRPELFCKLVGGPTAPGSGHTIQGQFCDYCNSEDSRKAHPAIHAIDGSERWWQSPPLSSGTQYNKVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGNTYSPWQYFAHSRGDCLQQFGQEANMAVTRDDQVLCVTEYSRIVPLENGEIVVSLINGRPGAKHFAFSDTLREFTKATNIRLRFLRTNTLLGHLISKAERDPTVTRRYYYSIKDISVGGRCVCNGHAEACSADNPEKQFRCKCQHHTCGDTCNRCCAGYNQRPWRPAAQDQHNECEACNCHGHAVDCYYDEAVSRQQASLNSKGVYTGGGVCIDCQHNTAGVNCEKCAKGYFRPHGVPVEALHGCIPCSCDPDRADECDQGSGRCHCKPNFSGDFCETCADGYYNFPFCLRIPVFPDYTLNPEDPMAGNIKGCDCNLEGVLPEICDDRGRCLCRPGVEGPRCDSCRSGSYSFPICQACQCSTSGSYPVPCDPETGQCECLPGVTGRRCDRCLSGAYDFPYCQGSSSVCDPAGTMDSSLGYCQCKLHVTSPTCSVCKPLYWDLAKENPRGCSECQCHEAGTVSGIGECGQEDGDCSCKAHVTGDACDTCADGYFSLEKSNYFGCQGCQCDIGGALTTMCSGPSGECQCREHIEGKQCQRPESNCYFPDLHHMKYEVEGGTGPNGRDLRFGFDPLEFPEFSWRGYVPMTSVQNEVKVRLTVRKSSLSLFRIILRYINPGMEEVSGRITVYSSRGKSDASQSKEITFPPSKEPAFVTVPGNGFADPFSITPGTWIACIQVEGVLLDYLVLLPRDYYEAFALQVPVTEPCAHTGSPQDNCLLYQHLPLTRFSCTLACEATHFLIDGERRPLAVRQPMPTHPAMVDLSGTEVELHLRLRVPQIGHYVVMLEYATEVDQLFVVDVNLKSPESALAGQVNIYSCKYSILCRSVVIDSLSRTAVYELLADADVQLKVHAARFLLHHICVIPAEEFSTEYLRPQVHCIASYGQSANPSASCVSVTHETPPTALILDATSGGHFSPLPHEPSSPADVTNGVTLKAPQNQVTLRGLIPHLGRHVFVVHFYQAEHPGFPTEVVVDGGRRWSGSFRASFCPHLLGCQDQVISEGQVEFDISEADVAVTVKIPDGKSLTLVRVLVVPAEDYDYHILHRTSVDKSSEFISSCGGDSFYIDPQAASGFCKNSARSLVAFYHNGAVPCECHPAGAAVHHCSPEGGQCPCRPNVIGRQCTRCATGYYGFPHCKPCNCGRRLCEEVTGKCLCPPNTVRPQCEVCEMNSFNFHPVAGCEVCNCSRKGTVEAAVSECDRDSGQCRCKPRVTGQQCDKCAPGFYHFPECVPCSCNRDGTEPGVCDPGTGACMCKENVEGPQCQFCREGSFYLDSANPEGCTRCFCFGVNTDCRSSHKRRAKFVDMMGWRLETADGVDVPVSFNPSSNSVVADLQELPSSVHSASWVAPPSYLGDKVSSYGGYLTYQAKSFGLPGDMVLLEKQPDVQLIGQHMSIIHAEPSDPRPDRPHHGRVQVVEGNFRHAGNSAPVSREELMAVLSSLEGLHIRGLHFTETQRLTLGEVGLEEASDTGSGPRAHLVEMCTCPPDYTGDSCQGCRPGYYRDIKSFPAGRCVPCNCNGHSNRCQDGSGVCINCQHNTAGEHCERCQEGYYGSAIHGSCRVCPCPHTN---SFATGCAVDGGAVRCACKPGYTGAQCERCAPGYFGNPQKFGGSCQPCNCNSNGQFGTCDPLTGDCVS-QEPKDGSPAEECDDCDSCVMTLLNDLVSMGEELRLVKSRLQGLSVSTGALEQIRHVEMQAKDLRNQLLGFRSAISSHGSKMDGLEKELSHLNQEFETLQEKAQVNSRKAQTLYNNIDQTIQNAKELDMKIKNIIQNVHILLKQIARPGGEGMDLPVGDWSRELAEAQRMLRELRGRDFKKHLQEAEAQKMEAQLLLNRIRTWLESHQVENNGLLKNIRDSLNDYEAKLQDLRSVLQEAAAQGKQATGLNHENEGVLGAIQRQMKEMDSLKNDLTEHLATADASLLQTNSLLQRMDTSQKEYESLAAALNGARQELNDQVRELSRSGGKAPLVAEAEKHAQSLQELAKQLEEIKRNTSGDELVRCAVDAATAYESILNAIRAAEDAAGKAASASESAFQTVIKEDLPRRAKTLSSDSEELLNEAKMTRKRLQQEINPALNSLQQTLKTVSVQKDLLDANVTAVRNDLRGIQRGDIDSVVSGAKSMVRKANGITSEVLDGLSPIQTDLGRIKDSYGSTRHEDFNKALIDANNSVKKLTKKLPDLFVKIESINQQLLPLGNISDNVDRIRELIQQARDAANKVAIPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPDLRENGG--------TEDMFVMYLGNKDASKDYIGMAVVDGQLTCVYNLGDREAEVQIDQVLTESESQEAVMDRVKFQRIYQFAKLNYTKEATSNKPKAPAVYDLEGGSSNTLLNLDPEDAVFYVGGYPPDFELPSRLRFPPYKGCIELDDLNENVLSLYNFKTTFNLNTTEVEPCRRRKEESDKNYFEGTGYARIPTQPNAPFPNFIQTIQTTVDRGLLFFAENQDN--FISLNIEDGNLMVRYKLNSEPPKEKGIRDTINDGKDHSILITIGKLQKRMWINVNERSVRIEGEIFDFSTYYLGGIPIAIRERFNISTPAFQGCMKNLKKTSGVVRLNDTVGVTKKCSEDWKLVRTASFSRGGQMSFTNLDVPSTDRFQLSFGFQTFQPSGTLLNHQTRTSSLLVTLEDGHIELSTRDSNIPIFKSPGTYMDGLLHHVSVISDTSGLRLLIDDQVLRRNQRLPSFSNAQQSLRLGGGHFEGCISNVLVQRFSQSPEVLDLASKSTKKDASLGGCSLNKPPFLMLFKSPKRFNKGRIFNVNQLMQDAPQATRSTEAWQDGRSCLPPLNTKASHRALQFGDSPTSHLLFKLPQELLKPRSQFSLDIQTTSPKGLVFYTGTKDSFLALYVADGRVVFALGAGGKKLRLRSKERYHDGKWHTVVFGLNGGKARLVVDGLRAQEGSLPGNSTISPREQVYLGLPLSRKPKSLPQHSFVGCLRDFQLNSKPLDSPSARFGVSPCLGGSLEKGIYFSQGGGHVILANSVSLGPELKLTFSIRPRSLTGVLIHVGSQSGQRLSVYMEAGKVTTSVSSDAGGSVTSITPKQSLCDGQWHSVAVSIKQRILHLELDTDSSYTVAPLSFSPNSTRGSLHVGGVPDKLKMLTLPVWNSFFGCLKNIQVNHVPVPITEATEVQGSVSLNGCPDH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8N7TFA0-1", "uniprot_id": "A0A8N7TFA0_DANRE", "id": "A0A8N7TFA0-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSESMAWRTAVLRALISGTLFLLVSAGP------RPEHRSPQREEAEWIQR------------AQLNDAQRVQFPSLHDTQQVQIPTLED------------------------------GQRCPAGHYLDRSGLFP-RCVPCSCNGHSNECEENTGRCLNCADNTAGQRCELCKEGFYWSEARRKCTACPCPLGNQDNNFAVGCTETQSRIQCVCKTGHAGERCERCASGYYGDPLVYGGGCRPCRCAGN----LCDSKTGACRNSLELQDTNTEEQCEECDNCAQTLLNDLEKLEMELRRIKGQADFDSLRPSSKALLKQLEDAITATKNLVNTFSFAVNSQMPKIVQLEQDVINLADDMDSLKEEVRKRSGDSQKALANAENSHQRAKDLDTETQNLLTKIRELLKQLMDAKSDGSSLPSADLAKLLEKSENMVKDMEKRSFTTQKDAAKKEQAEANKFLEDVKNIVKQCDQ-NEEASKRVDGLLSNYETKLKELEDLLKQAENMVKKAKNLNDVNAQGLKDILKRVNDLQRERDVVRDQIVLATDQLKDTQDLLKMFNDGKTEYEQLAAQLNGAKTDLKKKLQTVSQAAAKEKLVQQAEEHAENMYKLAKELQDAVQNVSGRSGVQDALSGIEAYKNITDAVNAAEEAAKKAKEAADKALNDVSQGDLINRAQDLKTNGSNLLKTAKNTAKDLKGAT-KDLTEQKNRLQDAEKKKKALEEELLKIQDGLKGIQRDDIAKIIDAAKKTAAAANRSTSDTMDQLNDIKAEVKKISITP---TVSNMDNVLNNVDMTVKNVSGSIPSLLDKIDELNNQINYGNNVSDNINKIKELIEQARDAANRVVVPMKFTGVGHVELRPPADLADMRAFTALSLSLQRPEKPPARGDDAVVQQDEDDLFVMYLGKKNASGDYIGMVLRKNVLHFIYKLNGREYDIEAYN-ITESSSDLSFFDKIDLYRIYQDAEVTYTKQYTSINPMPPQTKENKGDLTRNLLDLQPDDVVFYVGGYPDNFTPPASLNYGKYKGCIEFSTFNEKFLSLYNFKNAVNINLETPCKRQIPLKSTESDYFEGSGYAKVLLERFPSNLQLVQRVETRAKDALLLYLGDKDDDFYYSASLEGGYLVLRGQEKDTILEPIRSNEQPVLSPGIDVRLILVNRKNLRVIIGTTEVKRDVNIPRKFLYYYIGGIPSILRERYNITVPALKACVKNILVSNVAPFIEEKVGIGRGCSDELLMVRKAEFGSGSALEKLREDFKLDD-VNLSMGFRSTKSDGILMENQKNNNFIKLSLENGFVVLYFGG---LIYTSTKQYQDGEWHYLTAVAKGQSVELRVDEEDVGQRLTGIFREQYSSNVVLGKNTYEGCVSNLYLRRPGSPYRAEDLSVYSSSGDVRLSTCSM---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 431, "similar_positions": 535, "identity": "12.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2302", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61362-1", "uniprot_id": "CH3L1_MOUSE", "id": "Q61362-1", "name": "Chitinase-3-like protein 1", "aln": "MHTSTEARMGMRAALTGFAVLMLLQSC-SAYKLVCYFTSWSQYREGVGSFLPDAIQPFLCTHIIYSFANISSDNMLSTWEWNDESNYDKLNKLKTRNTNLKTLLSVGGWKFGEKRFSEIASNTERRTAFVRSVAPFLRSYGFDGLDLAWLYPRLRDKQYFSTLIKELNAEFTKEVQPG-REKLLLSAALSAGKVAIDTGYDIAQIAQHLDFINLMTYDFHGVWRQ--ITGHHSP-----------LFQGQKDTRFDRYSN---------------VNYAVQYMIRLGAQASKLLMGIPTFGKSFTLASSENQLGAPISGEGLPGRFTKEAGTLAY-YEICDFLKGAEVHRLSNEKVPFATKGNQWVGYEDKESVKN---------KVGFLKEKKLAGAMVWALDLDDFQG-TCQPKEFFPLTNAIKDALA----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WTV1-1", "uniprot_id": "CH3L1_RAT", "id": "Q9WTV1-1", "name": "Chitinase-3-like protein 1", "aln": "----------MTLQLPGFAVLMLLQSC-SAYKLVCYYTNWSQYREGNGSCFPDALDHSLCTHIIYSFANIS-NNKLSTSEWNDVTLYGMLNTLKTRNPRLKTLLSVGGWSFGSERFSRIVSNAKSRKTFVQSVAPFLRTYGFDGLDLAWLYPGPKDKQHFTTLIKELKAEFTKEVQPG-TEKLLLSAAVSAGKVTLDSGYDVAQIAQHLDFINLMTYDFHGTWRH--TTGHHSP-----------LFRGQQDTGPDRFSN---------------VDYGVGYMLRLGAPTNKLVMGIPTFGKSFTLASSENQVGAPITGSGLPGRYTKEKGTLAY-YEICDFLRGAEVHRILGQQVPFATKGNQWVGYDDPESVKN---------KVKYLKNKQLAGAMVWAVDLDDFRGSFCGHNVHFPLTNAIKEALAVA--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36222-1", "uniprot_id": "CH3L1_HUMAN", "id": "P36222-1", "name": "Chitinase-3-like protein 1", "aln": "--------MGVKASQTGFVVLVLLQCC-SAYKLVCYYTSWSQYREGDGSCFPDALDRFLCTHIIYSFANIS-NDHIDTWEWNDVTLYGMLNTLKNRNPNLKTLLSVGGWNFGSQRFSKIASNTQSRRTFIKSVPPFLRTHGFDGLDLAWLYPGRRDKQHFTTLIKEMKAEFIKEAQPG-KKQLLLSAALSAGKVTIDSSYDIAKISQHLDFISIMTYDFHGAWRG--TTGHHSP-----------LFRGQEDASPDRFSN---------------TDYAVGYMLRLGAPASKLVMGIPTFGRSFTLASSETGVGAPISGPGIPGRFTKEAGTLAY-YEICDFLRGATVHRILGQQVPYATKGNQWVGYDDQESVKS---------KVQYLKDRQLAGAMVWALDLDDFQGSFCGQDLRFPLTNAIKDALAAT--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q15782-4", "uniprot_id": "CH3L2_HUMAN", "id": "Q15782-4", "name": "Chitinase-3-like protein 2", "aln": "---MGATTMDQKSLWAGVVVLLLLQGG-SAYKLVCYFTNWSQDRQEPGKFTPENIDPFLCSHLIYSFASIE-NNKVIIKDKSEVMLYQTINSLKTKNPKLKILLSIGGYLFGSKGFHPMVDSSTSRLEFINSIILFLRNHNFDGLDVSWIYPDQKENTHFTVLIHELAEAFQKDFTKSTKERLLLTAGVSAGRQMIDNSYQVEKLAKDLDFINLLSFDFHGSWEKPLITGHNSP-----------LSKGWQDRGPSSYYN---------------VEYAVGYWIHKGMPSEKVVMGIPTYGHSFTLASAETTVGAPASGPGAAGPITESSGFLAY-YEICQFLKGAKITRLQDQQVPYAVKGNQWVGYDDVKSMET---------KVQFLKNLNLGGAMIWSIDMDDFTGKSCNQG-PYPLVQAVKRSLGSL--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P3P0-1", "uniprot_id": "A0A8M1P3P0_DANRE", "id": "A0A8M1P3P0-1", "name": "", "aln": "--------MHISRAFAFLCLVVSVGAQRTQSRLSCYLDVLTPHTREGS-----------CTHIILPSVSSD--DELYLQSLTEN-EYDAIQRMKERNSALKILL---GLEIKSSRLKLMSANEASVGSFIQTLLTYLKEKRLDGLDVIWLDGTPSDTELFTDFLKSIKGVFEEEMRPL-----LLSASVKEPTDKTVASYDEQILSQYVDFISILPAQLQTDGQYISKTAQHWQDKQVDLQKLGLVMPGFLQRSRHRHHHRNHPKHDDTTAEEGKKDHVHLLNLYLGDQVCQAVKSGQLQFITLTSVSDEQSPIKEVLQQGFGGIGVVLIDLDVFGNSMCPNMTQKERATVESKAIMHSHHGHRRHGHGDHRHHHTGHHTRHHTRHHDRHHGRHHHGRHHHGHRPHHHGHRHHGRHHHHHHHHSTTTQSSVTQVTPKGME", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . ::: : : :* ** : . . *:*:* . .. . : : . .: * :: :* :*. ** ** * : .. : : . *:.:: :*: :****: *: :. *: :::.: * :: **:*.:. .*: ::: :***.::. ::: . *.:: : * : . : :: : * : : . ::* .* * * * . . .: .:* : : .: : .: :*:: *: * . .. : : : * . ... . :: . . ", "identical_positions": 43, "similar_positions": 118, "identity": "9.77%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2303", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EP97-1", "uniprot_id": "SENP3_MOUSE", "id": "Q9EP97-1", "name": "Sentrin-specific protease 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKET--IQGTGSWGPEPPGPGT--TYSNPRRERLRWPLPPKPRLKS--------------------------GGGFGPDPGSGTTVPT----------------RRLPAPRPSFDASASEEEEEEEEED----EEEVAAWRLPPRWGQLGASQRSRALRPSHRKTCSQRRRRAMRAFQMLLYSKSTSLTFHWKLWGRHRGRRRNLAHPKNHLS---------------------------------------------------------------------------PQEGGATPQVPSPCCRFDS--------PRGLPPPRLGLLGALMAEDGMRGSPPVPSGPPMEEDGLRWTPKSPLDPDSGLLSCTLPNGFGGLSGPEGERSLAPPDASILISNVCSIGDHVAQELFQSSDLGIAEEADRTGEKAGQHSPLREEHVTCVQSILDEFLQTYGSLIPLSTDEVVEK-----LEDIFQQEFSTPSRKSLVLQLIQSYQRMPGNAMVRGFRVSYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEK------VHFFNSFFYDKLRTKGYDGVKRWTKN--VDIFNKELLLIPIH-LEVHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFHQG-WKGYFKMNVARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPKLRRQIYKELCHCKLTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LKC6-1", "uniprot_id": "A0ABK0LKC6_RAT", "id": "A0ABK0LKC6-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKET--IQGTGSWGPEPPGPGT--TYSNPRRERLRWPLPPKPRLKS--------------------------GGGFGPDPGSGTTVPT----------------RRLPGPRPSFDASASEEEEEEEEED----EEEVAAWRLPPRWGQLGTSQRPRALRPSHRKTCSQRRRRAMRAFQMLLYSKSTSLTFHWKLWGRHRGRRRNLAHPKNHLS---------------------------------------------------------------------------PQEGGATPQVPSPCCRFDS--------PRGLPPPRLGLLGALMAEDGMRGSPPVPSGPPMEEDGLRWTPKSPLDPDSGLLSCTLPNGFGGLSGPEGERSLAPPDASILISNVCSIGDHVAQELFQSSDLGTAEEADRPGEKAGQHSPLREEHVTCVQSILDEFLQTYGSLIPLSTDEVVEK-----LEDIFQQEFSTPSRKSLVLQLIQSYQRMPGNAMVRGFRVSYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEK------VHFFNSFFYDKLRTKGYDGVKRWTKN--VDIFNKELLLIPIH-LEVHWSLVSVDVRRRTITYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFHQG-WKGYFKMNVARQNNDSDCGAFVLQ---VFILETSFLY----MPIPGEQMAVRM-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H4L4-1", "uniprot_id": "SENP3_HUMAN", "id": "Q9H4L4-1", "name": "Sentrin-specific protease 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKET--IQGTGSWGPEPPGPGIPPAYSSPRRERLRWPPPPKPRLKS--------------------------GGGFGPDPGSGTTVPA----------------RRLPVPRPSFDASASEEEEEEEEEEDEDEEEEVAAWRLPPRWSQLGTSQRPRPSRPTHRKTCSQRRRRAMRAFRMLLYSKSTSLTFHWKLWGRHRGRRRGLAHPKNHLS---------------------------------------------------------------------------PQQGGATPQVPSPCCRFDS--------PRGPPPPRLGLLGALMAEDGVRGSPPVPSGPPMEEDGLRWTPKSPLDPDSGLLSCTLPNGFGGQSGPEGERSLAPPDASILISNVCSIGDHVAQELFQGSDLGMAEEAERPGEKAGQHSPLREEHVTCVQSILDEFLQTYGSLIPLSTDEVVEK-----LEDIFQQEFSTPSRKGLVLQLIQSYQRMPGNAMVRGFRVAYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEK------VHFFNSFFYDKLRTKGYDGVKRWTKN--VDIFNKELLLIPIH-LEVHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFHQG-WKGYFKMNVARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPKLRRQIYKELCHCKLTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BEN4-1", "uniprot_id": "A2BEN4_DANRE", "id": "A2BEN4-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRDSGSSLAQTHWSNELTLTAG--QEGAGGGGAIGGGHLMNPAMAQ--------------------------HAPSPAHFKLGRREED----------------VRMWGADYTVPEVEDEEEEEEEEEED-DVEMESGEDLEDQGIFHLQDQGDDKDWGTPEHSQVAEMDVRVTDDFTHCMAQRRPRLLKVRRLARLPNRGRRYLS--IRFRL---------------------------------------------------------------------------AQHWRTWRQRAKWAGTMGY--------RRVRRCHRRRYFGSQHFQR--------PPGRSLLNG----DPEGRLQGTEISDSCSTNGALKGRDGLHG-AVLGEREGRASPTNVQSQ-----------------------REKASLQNQLSSEHISCVQGILDEFLQQYGSLIPIHVDEVVEK-----LQEIFTESFSSPHRKIMVQHLMQSYQRMSGSAMMRGFRVNYKRHVLVMDDLTTLYGQNWLNDQVMNMYGDLVMDAAPEK------VHFFNSFFYDKLRTKGYEGVKRWTKN--VDIFQKKFLLIPIH-LEVHWSLVCVNVPQRSVTYFDSQRTLNRRCPKHIAKYLQAEAIKREQKDFYTG-WKGFFKMNVARQNNDSDCGAFVLQYCKCLALEQPFSFGQQDMPKLRRQMYKELCHCKLSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWK5-1", "uniprot_id": "Q9VWK5_DROME", "id": "Q9VWK5-1", "name": "", "aln": "MSLPPEDTDLSTNSAYESALQIASNVSAARVVGSAVGQRFSPSPAAHPNVIERVASHVDSRRSTFPSWGNPSVAPRGSEEAAANATATQLLWAENQGLPTSHLLPTEQAFETLNTNAYCSPPGDSRFTFPSQNYSPLLPRCVPVPNQRYSPDGSPIHQLHELQNCPLIDSPIRLRFPSPLPEPPSLPTITLTVDALIDLDQNNQVAYYVQQYNNQPVLYQQNIHIGTGIQLCDQASENNQPIILHIVEHNPQTITESQEQFHQVVPEIQINNIQEQDQKFENGISEQNHPIATEAQDQTLTEIRDENQIVLAVQEKNLTRASEIQDQNQQTLTEIPEKCLQIASPVTTDIQVQSPQVVIEIQEQNHQSVTEIQEEVHQTAPEIQVNVFQTSSDIQGQNHQIVTEEQNHQTITETQEDYSAVSEIQWENLSFSAEIQEQNQQIVTEVTKLASPSVTDIQAQSPQSVIEIQDDDDEDLKFESDDLHTIPEIQEKNQQSPQFVIEIHYDNEDLKFASDNQEQDQQTAELQKERFQFASEIEKRDLQIVTDTHKQNYHNVTDIPFATYIQEENEQLTPEDQEEDQHYLNFEGNQQFQLQKQDQLSVPQIQKQTHQFESKVKKRKLQPFSEYQQKGQKDHIQERQYIQQEFTIHSNQAYSKVQYIQTIQTATPYVPQLEISQENSFEVQPAYEVNEGQRDRELVSYTGHEHQNFVDEVSTPLPPAEAQPGSTSEDISDPVSPEHWEQLESLDPSTICIRKTFNLIRDISESLVADPEQPEAEAHRKSIFLLRQKLADVCHKVLTEIIHGRATDEIISILREILEQTKEIPPRPTPKRDLQEDISMGLEILKKIRGMLSGWYSSRESETDSTDTGTGFQAQNGKGFGAGRQPENSFLSQKRRNQEENPRLIKYRRVDNSFPRLITNETAEDLIPNNSMAKRDQPQSSKRLSIFNPPVYTQHRVRNDAPHVPTPFDDEESSQRLANAGPSSRPMTYSDAVRLGHNGISESRVNGHSSHTVRREPSRLHRSILSHEMNCKDQEQYNELIRTQTNYVGSRYLKPGTPPTFQRAKAQSATSSSCSLQDNQSNITDSFPSPHGRANPELTEYAKLINRQENEENRSPAPQQPKRNASNSSASHASTISSSASSSCSTCSTCSSSDTEPMLVKDSPEVKEANEANEANEANEANETKENDAPQPTTTRIKKPDFLHRRFANCIFLRNDFAENFKARANRRQLESMHLLGIAEQQANESKDERLAYEKKLREVMFRSGAPHRPFFEIGPLEQPEEKKETKLIPLTKEDHARFQEMTTIEVTTNLIFKYN-LQITTDDIFTFVDGEWLNDAIINFYMSMLTERSEKRAGELPATYAMNTFFMPRLLQAGYAGVRRWTRK--VDLFSKDIIPVPVHCGNVHWCMAIIHLRNKTIFYYDSMGRPNQPALDALVKYLHEESLDKRKQPFDMTGFVVENAQNIPRQGNSSDCGVFSCMFAEYITRDVPITFSQAEMLYFRTKMALEIADGKLWQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQH8-1", "uniprot_id": "Q8IQH8_DROME", "id": "Q8IQH8-1", "name": "Ubiquitin-like protease family profile domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLAFEKEIVEKSRYFDLITKECQDYPMAKTM--PVLK--------------------------------------QPEN------------------------------FQEQEEDVV----MAVQEK------LKFFR-------KLTSNGPAVPTPLKVVEKED-------------------IGHK--------------------------------------------------------------------------------------------------EIPKVVKKVDR------------------------------------------------KTKLLQAIPAVFKHSHN--------------------------------RRFRRSLFLRSNYIEQFRRWTDQKNKLNRKRLNEAHQLCLKAKHERIACEIDRYKKLILKQSVH---------VIEDIRISSELIPLTKEHHDRLMELSKYPLQQVIVAKFN-LDICGSDIKILTSGGWLNDKIINFYMNLLVERSEKRPGTVPSVYAMSTFFVPRLLQSGFDGVKRWTRK--VDLFSMDLILVPVHQMLVHWCLVIIDLPAKTMLYYNSRGRGDPNLMRALVKYLQMESEDKLGLCLDTSEFRIEDAQNVPQQDNMNDCGVFVCMFAEYLTRDAPITFSKKDMKYFRTKMVLELTGDQLWK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02724-1", "uniprot_id": "ULP1_YEAST", "id": "Q02724-1", "name": "Ubiquitin-like-specific protease 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVEVDKHRNTLQYHKKNPYSPLFSPISTYRCYPRVLNNPSESRRSASFSGIYKKRTNTSRFNYLNDRRVLS---------------------------MEESMKDGSDRASKAGFIGGIRETLWNSGKYLWHTFVKNEPRNFDGSEVEASGNSDVESRSSGSRSSDVPYGLRENYSSDTRKHKFDTSTWALPNKRRRIESEGVGTPSTSPISSLASQKSNCDSDNSITFSRDPFGWNKWKTS-----------------------------------------------------------------------AIGSNSENNTSDQKNSYDR-----------RQYGTAFIRKKKVAKQNINNTKLVSRAQSEEVTYLRQIFNGEYKVPKILKEERERQLKLMDMDKEKDTGLKKSIIDLTEKIKTILIENNKNRLQTRNENDDDLVFVKEKKISSLER--KHKDYLNQKLKFDRSILEFEKDFKRYNEILNERKKIQEDLKKKKEQLAKKKLVPELNEKDDDQVQKALASRENTQLMNRDNIEITVRDFKTLAPRRWLNDTIIEFFMKYIEKSTPNT-------VAFNSFFYTNLSERGYQGVRRWMKRKKTQIDKLDKIFTPINLNQSHWALGIIDLKKKTIGYVDSLSNGPNAMSFAILTDLQKYVMEESKHTIGED--FDLIHLDCPQQPNGYDCGIYVCMNTLYGSADAPLDFDYKDAIRMRRFIAHLILTDALK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . .* . . : . . : .. . . . : :. . . : . . . . : *: : **** ::::: . : . : :.:** .* *: **:** :. .:: . . : *:: **.: :.: ::: * :* : . *: .. : : .:* * *** : . .: : : : ", "identical_positions": 26, "similar_positions": 77, "identity": "1.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2308", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A4I3-1", "uniprot_id": "D4A4I3_RAT", "id": "D4A4I3-1", "name": "Phosphoinositide 3-kinase regulatory subunit 5", "aln": "-----MQPAATTCTEDRIQHALERCLHGLSLG-RRSAPWSAGLCLNCWSLQELVSRDPGHFLILLEQILQKTQEVQEKGTYDLLAPLALLFYSTVLCTPHFPPDSDLLLKAASTYHCFLTWPVPYCSICREMLTFIDAELKAPGISYQRLVRAEQGLPIRSHRSSTVTVLLLNPVEVQAEFLAVADKLSTPGQSPHGAYTTLLLHAFQATFGTHCDLPKLHRKLQSKTLEELEDIFTETTEAQELASGIGDVAEARQWLRTKLQAVGEKAGFPGILDTASPGKLHTIPIPVARCYTYSWNQDSFDILQEVLLKEQELLQPGILGDDEEEEEE---------DLEIDRHIAERDSLLSTGSLVSHDSELLLTSSQASGPVLSRQVLTTFVSGLSDGMDSGYVEDSEESSSEWPKKPGSQQRQGHRRPRQKFNRFYKLLKSTSQLVLRRDSRSLECSPDPTLPLRRAGSLSSPLDFPTQLPSRAQRSRSLPQ-PKLSTQLPSWLLAPPSHHQ----RRRPFLSGDED---PKASTLRVVVFGSDRISGKVARAYSKLRRLENSHPILTRFFKLQFFYVPVKRSHGASSSACLSSLNQASPLLPDSLKHPSPADLGKAPWEDSTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQQSLKAESRPLEGS-ATQLPILADMLLYYCRFAARPVLLQVYQTELTFVTGEKTTEIFIQSLELGHSATTRAIKASGPGSKRLGIGDDREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLSKACQKPEELDSSMEALTLTLTEVVKRQNPKSKKGFN-QISTSYIKVDKVQIISSSSCPFAVCLDQDERKILQSVVRCEVSPCYKPEKS--SLPPEGSLSQPAEAGSDLCSLLCLPIMTFSGALP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SW28-1", "uniprot_id": "PI3R5_MOUSE", "id": "Q5SW28-1", "name": "Phosphoinositide 3-kinase regulatory subunit 5", "aln": "-----MQPAATTCTEDRIQHALERCLHGLSLG-RRSAPWSAGLCLNCWSLQELVSRDPGHFLILLEQILQKTQEVQEKGTYDLLAPLALLFYSTVLCTPHFPPDSDLLLKAASTYHCFLTWPVPYCSICREMLTFIDAELKAPGISYQRLVRAEQGLPVRSHRSSTVTVLLLNPVEVQAEFLAVADKLSTPGQSPHGTYTTLLLHAFQATFGAHCDLPKLHRKLQSKTIEELEDIFTETTEAQELASGIGDVAEAREWLRTKLQAVGEKAGFPGILDTASPGKLHTIPIPVARCYTYSWNQDSFDILQEVLLKEQELLQPGILGDDEEEEEE---------DLEMDRHCAERDSLLSTSSLVSHDSTLLLTSSQASEPVLSRQMLTTFVSGLSDGMDSGYVEDSEENS-EWPQKPGSQKRQGHRRPGQKFNRFYKLLKSTSQLVLRRDSRSLESSVDPTLPLRRAGSLCSPLDCPAQLPSRAQRSRSLPQ-AKLTTQLPRWLLAPPSHHQ----RRRPFLSGDED---PKASTLRVVVFGSDRISGKVARAYSKLRRLETSHPILTRFFKLQFFYVPVKRSHGTSPSACPSSLSQASPLPADSLKYPSPTDLGMAPWEDSTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQQSLKADSRPLEGS-ATQLPILADMLLYYCRFAARPVLLQVYQTELTFVTGEKTTEIFIQSLELGHSATTRAIKASGRGRKRLGIDDDREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLSKACQKPEELDSSMEALTLTLTEVVKRQNPKSKKGFN-QISTSYIKVDKVQIIGSSSCPFAVCLDQDERKILQSVVRCEVSPCYKPEKS--SLPPERSFSQPAETGSDLCSLLCLPIMTFSGALP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WYR1-1", "uniprot_id": "PI3R5_HUMAN", "id": "Q8WYR1-1", "name": "Phosphoinositide 3-kinase regulatory subunit 5", "aln": "-----MQPGATTCTEDRIQHALERCLHGLSLS-RRSTSWSAGLCLNCWSLQELVSRDPGHFLILLEQILQKTREVQEKGTYDLLTPLALLFYSTVLCTPHFPPDSDLLLKAASTYHRFLTWPVPYCSICQELLTFIDAELKAPGISYQRLVRAEQGLPIRSHRSSTVTVLLLNPVEVQAEFLAVANKLSTPGHSPHSAYTTLLLHAFQATFGAHCDVPGLHCRLQAKTLAELEDIFTETAEAQELASGIGDAAEARRWLRTKLQAVGEKAGFPGVLDTAKPGKLHTIPIPVARCYTYSWSQDSFDILQEILLKEQELLQPGILGDDEEEEEEEEEVEE---DLETDGHCAERDSLLSTSSLASHDSTLSLASSQASGPALSRHLLTSFVSGLSDGMDSGYVEDSEESSSEWPWRRGSQERRGHRRPGQKFIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLPQ-PKLGTQLPSWLLAPASRPQ----RRRPFLSGDED---PKASTLRVVVFGSDRISGKVARAYSNLRRLENNRPLLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDSPRHASPGELGTTPWEESTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQQSLKAEAQALEGS-PTQLPILADMLLYYCRFAARPVLLQVYQTELTFITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDGDREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSMEALTLNLTEVVKRQNSKSKKGFN-QISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSVVRCEVSPCYKPEKSDLSSPPQTPPDLPAQAAPDLCSLLCLPIMTFSGALP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TLL8-1", "uniprot_id": "A0AB32TLL8_DANRE", "id": "A0AB32TLL8-1", "name": "Phosphoinositide 3-kinase regulatory subunit 5", "aln": "MFSVPVKMQHTSCTEDRIQHALDRCLDGLRPSENLSQSWSAGWCMNRWSLEELIKRDPDNFLILLQQILRKAREVQQECHYELVAPLALMFESTLLQMPLCPSSEKVLTEACEVFHGFLAWPEPYCSVCRNLLSTLHQELRAPGISYHRLVREEQGLATSSQRSKIITVFLMNPTEVPPEFLSVAEQLSSIEVSQRESCVTLIKHSYQSVLGTKYPLHTINSALQCLSDDELAQIMSSVSDLLESAAAMVDIAKARKHVEGGLEVLREKLGIPSSNGKMSDGVLQTLGLPAAKCYTFHWDKDNFDVLNDILDIESELTLSQTSESMEEDDVDNVDVEDDEYDDLEDVCTDYRASTFSTVSSLSTASKDSMFSTLSVASSECSPLSTLSSSSQASGTDSDFCEDLEDDS---SSTVSPSKTKNSGRLSKRISRFFKPRSSNS--------------------LCRAKSLGSPEAKELVVAVRSKRSNSLPQQVHLRSSDFGFPVIPLSQLQYVCYRRRPILSTDDEEGPTGATLLRVVVFGADHVAGRLARAYSSLRKRERDCPHLTKAFRMKFFFVPVRRDTAPVNSRRSSLQLSASPLKT----AISTTDLCVNRMEDSTNDIANLLGMLDPWYERNTLSLMELPVNVVCQQTSKIDSDLSEGTGEERLPIFADLVLYYCRHAARPALIQLYQAEFTLAGGVRRTEVFIHSLELGHTAGTRAIKAMGAASKRFGIDGDREAVPLSLEITYNRIHISGRSQKTRTEKSCTSINLQKACRNSEELDSKMECLRLTMTEVLKRQNSKSKKGYNQQLTTTEVKVDKVQVSGTCNTTFAVCLDQDEKKILQSVMRCEVSVCYKPDSSTDWTRGRVFSSQTQLLQPTFCSLLCLPVATFSGPQP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: *:**********:***.** . . * .**** *:* ***:**:.***.:*****:***:*::***:: *:*::****:* **:* * *....:* :*...:* **:** ****:*:::*: :. **:******:**** ****. *:**. :**:*:**.** .***:**::**: * : : .**: *::*:.:*:: : :: **. : ** :*::..:: * *:.: * *:**. :. *:.: ** *:*. .. . * *:*: :*.*:***: *.:*.**:*:::* *.** . . **:: : * * * * :** * * * : *: : . . : * *. :.* **.: ** *:.* . ...: :. * ::: *::* .*.* * ** ** ** . *::**.**** :* :. : : * *: * ****:** *:: . *: *******:*:::*::*****.**: * . * **: *:::**:***:*. .. . . .:.. . *. :* *:*****:: ***********.*.**.** :*:***: * :: **: :***:**::*****.****.*:*:**:*:*: * : **:**:******:* ****** * . **:**..*******:*:* *.: *****: :. ** ***:**.***:: *****.**.* *.:***:****.*****:* *::*: :******: .: . .*********:******:***** ****:.* . . . . :*******: ****. *", "identical_positions": 385, "similar_positions": 253, "identity": "42.83%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2310", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ATX5-1", "uniprot_id": "A0A8I6ATX5_RAT", "id": "A0A8I6ATX5-1", "name": "StAR-related lipid transfer protein 7, mitochondrial", "aln": "MFPRRPP---------------------------------------ATLAAWLAGARGGG-----------LLAALANQCRFVTGLRVRRAQQIAQLYGRLYSESSRCALLGRFWRRLRGRPGHASALMAA-LSGV---------FVWDEERIQEEELQRSINEMKRLEEVSNIFQSSGVESHPPETKCPAEGNEKSK-------------------------------------------DKEEPWEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRKKWDALVIKLEVIERDAVSGSE--VLHWVTHFPYPMYSRDYVYVRRYSVDQENNVMVLVSRAVEHPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLLTYSDNPQTVFPRYCVSWMVSSGMPDFLEKLHTATL-----KAKNMEIKVKDYISAKPLEMSSEAKATASSPERKNEGSCGPARIEYA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1R3-1", "uniprot_id": "STAR7_MOUSE", "id": "Q8R1R3-1", "name": "StAR-related lipid transfer protein 7, mitochondrial", "aln": "MFPRRPP---------------------------------------ATLAAWLAGARGGG-----------LLSALANQCRFVTGLRVRRAQQIAQLYGRLYSESSRCALLGRFWRRLRGRPGHASVLMAA-LSGV---------FVWDEERIQEEELQRSINEMKRLEEMSNIFQSSGVENYPPEPKSPAGGNEKSK-------------------------------------------DKEEPWEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRKKWDALVIKLEVIERDAVSGSE--VLHWVTHFPYPMYSRDYVYVRRYSVDQENNVMVLVSRAVEHPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLLTYSDNPQTVFPRYCVSWMVSSGMPDFLEKLHMATL-----KAKNMEIKVKDYISAKPLEMSSEAKATAPSPERKNEGSCGPARIEYA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQZ5-1", "uniprot_id": "STAR7_HUMAN", "id": "Q9NQZ5-1", "name": "StAR-related lipid transfer protein 7, mitochondrial", "aln": "MLPRR------------------------------------------LLAAWLAGTRGGG-----------LLALLANQCRFVTGLRVRRAQQIAQLYGRLYSESSRRVLLGRLWRRLHGRPGHASALMAA-LAGV---------FVWDEERIQEEELQRSINEMKRLEEMSNMFQSSGVQHHPPEPKAQTEGNEDSE-------------------------------------------GKEQRWEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRKKWDALVIKLEVIERDVVSGSE--VLHWVTHFPYPMYSRDYVYVRRYSVDQENNMMVLVSRAVEHPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLLTYSDNPQTVFPRYCVSWMVSSGMPDFLEKLHMATL-----KAKNMEIKVKDYISAKPLEMSSEAKATSQSSERKNEGSCGPARIEYA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UVX5-1", "uniprot_id": "A0A8N7UVX5_DANRE", "id": "A0A8N7UVX5-1", "name": "StAR-related lipid transfer protein 7, mitochondrial", "aln": "MFPSVQHRPVCSIGARAVRLQSISSFSNSGAKSSKSFRFSWLGERVGLLMSWLQKAGRGTNKLASDNKKEKLLSIFANHCSFVTGQRLRRAFQIGELYSNLYSERTRWTLVGSIWRRLQSKHAPTGKLVAA-LAGV---------FMWEDEKIRDDELRRCAWELQAVESVRSQDVSPKVATH-----------------------------------------------------------VDQGWEVVMEKKNFRVWRRPVEGSHLFEYRVFGSYTDVTPRQFFNVQLDTEYRKKWDALVIRLDVVDRDVNTGTE--VVHWATHFPYPMYSRDYVYVRRYQVDLENNLMILVSRAVKHPCVPETQEFVRVHSYQSKMVIRPHRSFDENGFDYLLTYSDDPQTVFPRYCVSWMVSSGMPDFLEKLHTAAL-----RAKNMDVSVHDYVNVVKPSQPSQEQRLG----AENTHTAGSSQIYA-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJZ2-1", "uniprot_id": "Q9VJZ2_DROME", "id": "Q9VJZ2-1", "name": "START domain-containing protein", "aln": "----------------------------------------------MLFNRFVLAIKNQS---------RETLRAWSYQCESIFAQRSRRVQQLFSFYQSVYGTQGLKQLWRAYYRRELQPPLRGMVMSAVGLVGLNIKRMGSDGFDWNKERLALSNFDLCRRDIEFINALPNNQLCDRCQAKKMKYCYCQLGNQRCKKGQSQPSTSKEAETDPDTSISNCLRPLDLDVRNAPAGTVRIQAQDDQKWEPYFSKNEFSIWRRQER-SSLYSYKVYARFDDITADDFLHVQTDLDYRRQWDDTALRLELISEDPVPGSNSHLIYWEMQWPRLFANRDYVYCRRYIKDDNKKLIFICNRGATHNTYPALSGKVRVTDYWSLMVIKPFRGFHEPGLHFVLTYFDDPGIPIPQNIKSWVTQKQMPEFLTKMYVATKNYACSRAIKMKDMFHGFALINDEYTANEQRGSWLGSLSRRKVNSKPEAGR--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: * : :* : . * **. *: .:* :*. * :** : *. * *: * *:.*:: .:: . ::: :: : . . :: ** :.*:.* :*** : *:.*:*:. : *:*. :*::** * :**::** .::*:::..* .*:: :::* ::* : .***** *** * :::::.: .*.. * * *** .* * ***:*.:.*.* *:.::*** *:* :*: **:... **:** *:: *: :* :*. .:.: ..: : .. .. . ", "identical_positions": 82, "similar_positions": 120, "identity": "16.98%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2317", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q01844-1", "uniprot_id": "EWS_HUMAN", "id": "Q01844-1", "name": "RNA-binding protein EWS", "aln": "-MASTDYSTYSQAAAQQGYSAYTAQPTQ-GYAQ-TTQAYGQQS-YGTYGQPTDVSYTQAQ-TTATYGQTAYATSYGQPPTG----YTTPTAPQAYSQPVQGYGTGAYDTTTATVTTT---QASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQ-PPTSYPPQTGSYSQ-APSQYSQQSSS---YGQQ--------SSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGG--RGGG-RGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG-GRGGDRGGFPPRG-PRGS-RGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGG--MFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMD-KGEHRQERRDRPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61545-1", "uniprot_id": "EWS_MOUSE", "id": "Q61545-1", "name": "RNA-binding protein EWS", "aln": "-MASTDYSTYSQAAAQQGYSAYTAQPTQ-GYAQ-TTQAYGQQS-YGTYGQPTDVSYTQAQ-TTATYGQTAYATSYGQPPTG----YSTPTAPQAYSQPVQGYGTGTYDSTTATVTTT---QASYAAQTAYGTQPAYPTYGQQPTATAPTRPQDGNKPAETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSSQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQ-PPTSYPPQTGSYSQ-APSQYSQQSSS---YGQQ--------SSFRQDHPSSMGVYGQESGGFSGPGENRSLSGPDNRGRGRGGFDRGGMSRGG--RGGG-RGGLG-AGERGGFNKPGGPMDEGPDLDLGLPIDPDEDSDNSAIYVQGLNDNVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGMPPREGRGMPPPLRGGPGGPGGPGGPMGRMG-GRGGDRGGFPPRG-PRGS-RGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGG--MFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMD-KGEHRQERRDRPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4J1A5-1", "uniprot_id": "A0A0B4J1A5_DANRE", "id": "A0A0B4J1A5-1", "name": "", "aln": "MASAADYNSYGQAGSQQGYGSYPAQPSQPGYGQGTQQSYGQQQGYGSYSQPADSTYSQTSGSSSSYGQQPYGSSYGQQPPASGSYNAASATPQGYTQPVQGYGSSSYDSSTAAASSTSNTQTSYGGQASYGTQSAYPGYGQQPAAAAP--------------PSSYSSGSQQP-AGYEQS---------SYSQQP-------QQSTYSQQQQGGYQ----GQQGGYGQQSSYSQQGGYQQTPPQQQQAPPSSYAPPSGSYGQPSASQYGQQGSTGGGYGQSDYKPPNQYGSYRPDHQNGGGYSGPESGGYGGPGEGRGMGGGENRGRGRGGFDRGMMRGGGGMRGGMSRGGMGIAGDRGGFSKPG-------DGEMGAPEEQD-DSENSTIYITGLTENATLEEVADFFKHSGIIRINKRTGLPAVNIYTDKDTGKPKGDATLSYEEPPSAKAAVEWFDGKDFQGKKLKVSMARRKPMMGMMRGGMP----------MRGDRGGMMGRGGMMGRGGMGRGGDRGGFMPRGGPRGMGRGGPTGG-NMQQRAGDWQCPNAGCGNQNFAWRMECNQCKAPKPEGFGPPPFPP-GGDRGRGGPGGMRGGRG--MDRGGPGGPGGFRGGRGVDRGGFRG-RGMDRGGFGGRGRGGPP------MDDMGRRGRGMGPPGKMDMKGDHRQDRRERPY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::**.:*.**.:****.:*.***:* **.* * *:****. **:*.**:* :*:*:. ::::*** .*.:**** *.. ::.::**.*:*******:.:**::**:.::* *:**..*::****.*** *****:*:** *.* :.* :** ** ** **. ** ::**. * .*: .**. *** ***.**..* * .. ** **:**.* :***.* :.***.**.*: ***. .*:* ** .. * * ****:.****.*.:.* :************ * ** *** ***:* **:****.*** * ::* * : * **:**:**: **.:..**:::*****:.*::::***** * ::** **:*********:***:**:***************.*****:**:** *. ****:* :**. ** * ** *** * ********* *** *** **.*:** *:*:*********.********** ************* ****** ***************** ******** ****** ******* ********** **** *::** * * * ***** **:***:**:***", "identical_positions": 388, "similar_positions": 138, "identity": "56.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2327", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H3N1-1", "uniprot_id": "TMX1_HUMAN", "id": "Q9H3N1-1", "name": "Thioredoxin-related transmembrane protein 1", "aln": "MAPSGSLAVP--------LAVLVLLLWGAPWTHGRRSNVRVITDENWRELLEGDWMIEFYAPWCPACQNLQPEWESFAEWGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHCKDGEFRRYQGPRTKKDFINFISDKEWKSIEPVSSWFGPGSVLMSSMSALFQLSMWIRTCHNYFIEDLGLPVWGSYTVFALATLFSGLLLGLCMIFVADCLCPSKRRRPQPYPYPSKKLLSESAQPLKKVEEEQEAD--EEDVSEEEAESKEGTNKDFPQNAIRQRSLGPSLATDKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VBT0-1", "uniprot_id": "TMX1_MOUSE", "id": "Q8VBT0-1", "name": "Thioredoxin-related transmembrane protein 1", "aln": "MAHLGRLMVP--------LAALVLLLWAVPGAHGRRNNVRVLTDENWTSLLEGEWMIEFYAPWCPACQNLQPEWESFAEWGEDLEVKVAKVDVTEQTGLSGRFIITALPSIYHCKDGEFRRYVGPRTKKDFINFVSDKEWKNIEPISSWFGPSSVLMTMMSALFQLSVYIRTSHSYFVHDLGIPAWGSYLVFAFATVLSGLLLGLCMIFVADCLCPSKRRKPQ--QQYAKKTSPEFSQPLKKVEEEQEAD--EEDVSEEEAEDREGASKATSQSSIRQRCVGLPSATDTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1Q6B4-1", "uniprot_id": "F1Q6B4_DANRE", "id": "F1Q6B4-1", "name": "Thioredoxin-related transmembrane protein 1", "aln": "MACGDPRRVRGMTAGACVLSILAACVVAQPEAP-KAGQLRVLTDGDWQEVLTGEWMIEFFAPWCPACQQLEPVWTEFAGWGDDLGVNIAKVDVTEHPGLSGRFIIMALPTIYHCKDGVFRRYQGDRSKEDFLSFIEEKKWQSIEPVSSWFGPSSFLMNIMSALFKLSVFIRHCHNYLTEQMGFSVWESYGIFACATIVAGLFLGLVMVFVADFVFPSRRFSPD---YHHRKLPARQVCCQHQFEYEQEADGEEEDDEYEYGGALDTLPRMDATDAHRRRPVHLREEDT--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . * *: *. : . * : : .::**:** :* .:* *:*****:********:*:* * .** **:** *::*******:.******** ***:******* **** * *:*:**:.*:.:*:*:.***:******.*.**. *****:**::** .*.*: .::*:..* ** :** **:.:**:*** *:**** : **:* *: :* .. ::.* ***** *** . * . : : . .: *:* : ", "identical_positions": 131, "similar_positions": 75, "identity": "45.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2333", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W3C4-1", "uniprot_id": "Q9W3C4_DROME", "id": "Q9W3C4-1", "name": "beta-N-acetylhexosaminidase", "aln": "MRFSGYNRYQCFCSAVGSLLLLSLLSFAVGAALTRADDVG-----SDADAGSASRKWLCSRTDICTAEGEMVAGLQY-APEIFESQRDCRLSCG-KYGAIWPMPTG-KECTISHRRVRFDPWKVRFHVVAPGEAATQFLRETNRLFVSNLLKECIRNCTLETSKQILVRSTVAN-------------------------------------ESLVLDWPTDESYALVVRTTET-ATFVDIQATTVYGARHAFETLSNLVTGSLSNGLLMVTT-ANITDRPAFSHRGVLLDTARNFVPLKFIRSTLDAMAASKLNVLHWHVVDTHSFPLEITRVPEMQRYGAYS-SSQTYSRQDALNLVKYARLRGIRILIEIDGPSHAGNGWQWGPAAGLGNMSVCLNQSPWRRFCVQPPCGQLNPLNDHMYAVLKEIFEDVAEVGAPEETLHMGGDEVFLPCWNNTDEIRDGMRARGYDLSEQSFLRLWSQFHQRNLNAWDEINERMYPGIKEPKSVIIWSSHLTNPRYIETYLPKERFIIQTWVES--QDALNRELLQRGYRLIVSTKNAWYLDHGFWGS--------TSYYNWRTVYSSG----MPVGRS-KDQVLGGEVCMWSEYVDQNSLESRIWPRAGAAAERMWSNPKS------SALLAQRRFYRYRERLLARGIHADAVIPHWCVLHEGQCL------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8WSF3-1", "uniprot_id": "FDL_DROME", "id": "Q8WSF3-1", "name": "Probable beta-hexosaminidase fdl", "aln": "MSLAVSLRRALLVLLTGAIFILTVLYWNQGVTKAQAYNEALERPHSHHDASGFPIPVEKSWTYKCENDRCMRVGHHG-KSAKRVSFISCSMTCG-DVN-IWPHPT--QKFLLSSQTHSFSVEDVQLHVDTAHREVRKQLQLAFDWFLKDLRLIQRLDYVGSSSEPTVSESSSKSRHHADLEPAATLFGATFGVKKAGDLTSVQVKISVLKSGDLNFSLDNDETYQLSTQTEGH-RLQVEIIANSYFGARHGLSTLQQLIWFDDEDHLLHTYANSKVKDAPKFRYRGLMLDTSRHFFSVESIKRTIVGMGLAKMNRFHWHLTDAQSFPYISRYYPELAVHGAYS-ESETYSEQDVREVAEFAKIYGVQVIPEIDAPAHAGNGWDWGPKRGMGELAMCINQQPWSFYCGEPPCGQLNPKNNYTYLILQRIYEELLQHTGPTDFFHLGGDEVNLDCWAQY-------------FNDTDLRGLWCDFMLQAMARLKLANNGVAP-----KHVAVWSSALTN----TKCLPNSQFTVQVWGGS--TWQENYDLLDNGYNVIFSHVDAWYLDCGFGSWRATGDAACAPYRTWQNVYKHRPWERMRLDKKRKKQVLGGEVCMWTEQVDENQLDNRLWPRTAALAERLWTDPSDDHDMDIVPPDVFRRISLFRNRLVELGIRAEALFPKYCAQNPGECI------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E8H9-1", "uniprot_id": "Q0E8H9_DROME", "id": "Q0E8H9-1", "name": "beta-N-acetylhexosaminidase", "aln": "--------MKSTRTALGVALLLALVSQLAAHSSD-----------------------DLVYGYECRSGYCQKVELSEENYVKAISLPVCRLFCGSSIGTLWPKPTGTVRLDTLMRQVDISFIDFNFNGIARQQKLWRAVEDRFMNMLEAQIPDRKVLARGGYRMSVNINTPDEP-------------------------------------TPARLTLDTDESYTLDIDTDASGHVLANITASNFFGARHGLETLAQLIVYDDIRREVQVTANATINDAPVYKWRGLLLDTSRNYYSVKSIKRTLEGMALVKLNTFHWHITDSHSFPLEVKKRPELHKLGAYS-QRQVYTRRDVAEVVEYGRVRGIRVMPEFDAPAHVGEGWQHKN------MTACFNAQPWKSFCVEPPCGQLDPTVNEMYDVLEDIYGTMFDQFNP-DIFHMGGDEVSTSCWNSSQPIQQWMKKQGWGLETADFMRLWGHFQTEALGRVDKVANGTHT------PIILWTSGLTEEPFIDEYLNPERYIIQIWTTG--VDPKVKKILERGYKIIVSNYDALYLDCGGAGWVTDGNNWCSPYIGWQKVYDNS---LKSIAGDYEHHVLGAEGAIWSEQIDEHTLDNRFWPRASALAERLWSNPAEG------WRQAESRLLLHRQRLVDNGLGAEAMQPQWCLQNEHECPIDACSRGSGRLGLIVLLLLTTLSA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6AXR4-1", "uniprot_id": "HEXB_RAT", "id": "Q6AXR4-1", "name": "Beta-hexosaminidase subunit beta", "aln": "----------------------------MPGSP----------------------------------RRAPG-LLLQALVAMVSLALVAP---FGLQPALWPMPRSVQVFPRLLYISPENFQIDNSPNSTAGPSCSLLLEAFRRYYNYIFGFYKRHHGPAKFQDKPQLEKLLVFIN-------------------------------LEPQCDAFPSMSSDESYSLLVQEPVA-----LLKANEVWGALRGLETFSQLVYQDAYG--TFTINESTIADSPRFPHRGILIDTSRHYLPVKTIFKTLDAMAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYS-LSHVYTPNDIHMVLEYARLRGIRVIPEFDSPGHTQS-WGKGQK---NLLTPCFIQK-----IRTQKVGPVDPSLNTTYVFFDTFFKEIS-RVFPDQFIHLGGDEVEFECWASNPNIQNFMKKKGFGNNFRRLESFYIKKILDIITSLKKSS-------------IVWQDVFDD-----QVELQPGTVVEVWKSE-NYLNELAQVTASGFPAILS--APWYLDL------------ISYGQDWRNYYKAEP-LNFEGSEKQKQLVIGGEACLWGEYVDATNLIPRLWPRASAVGERLWSPRIIT-----NLENAYRRLAVHRCRMVSRGIAAQPLFTGYCNYENKMEK------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20060-1", "uniprot_id": "HEXB_MOUSE", "id": "P20060-1", "name": "Beta-hexosaminidase subunit beta", "aln": "----------------------------MPQSP----------------------------------RSAPGLLLLQALVSLVSLALVAP---ARLQPALWPFPRSVQMFPRLLYISAEDFSIDHSPNSTAGPSCSLLQEAFRRYYNYVFGFYKRHHGPARFRAEPQLQKLLVSIT-------------------------------LESECESFPSLSSDETYSLLVQEPVA-----VLKANSVWGALRGLETFSQLVYQDSFG--TFTINESSIADSPRFPHRGILIDTSRHFLPVKTILKTLDAMAFNKFNVLHWHIVDDQSFPYQSTTFPELSNKGSYS-LSHVYTPNDVRMVLEYARLRGIRVIPEFDTPGHTQS-WGKGQK---NLLTPCYNQK-----TKTQVFGPVDPTVNTTYAFFNTFFKEIS-SVFPDQFIHLGGDEVEFQCWASNPNIQGFMKRKGFGSDFRRLESFYIKKILEIISSLKKNS-------------IVWQEVFDD-----KVELQPGTVVEVWKSE-HYSYELKQVTGSGFPAILS--APWYLDL------------ISYGQDWKNYYKVEP-LNFEGSEKQKQLVIGGEACLWGEFVDATNLTPRLWPRASAVGERLWSPKTVT-----DLENAYKRLAVHRCRMVSRGIAAQPLYTGYCNYENKI--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07686-1", "uniprot_id": "HEXB_HUMAN", "id": "P07686-1", "name": "Beta-hexosaminidase subunit beta", "aln": "---------------------MELCGLGLPRPPMLLALLL-----------------------ATLLAAMLALLTQVALVVQVAEAARAPSVSAKPGPALWPLPLLVKMTPNLLHLAPENFYISHSPNSTAGPSCTLLEEAFRRYHGYIFGFYKWHHEPAEFQAKTQVQQLLVSIT-------------------------------LQSECDAFPNISSDESYTLLVKEPVA-----VLKANRVWGALRGLETFSQLVYQDSYG--TFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYS-LSHVYTPNDVRMVIEYARLRGIRVLPEFDTPGHTLS-WGKGQK---DLLTPCYSRQ-----NKLDSFGPINPTLNTTYSFLTTFFKEIS-EVFPDQFIHLGGDEVEFKCWESNPKIQDFMRQKGFGTDFKKLESFYIQKVLDIIATINKGS-------------IVWQEVFDD-----KAKLAPGTIVEVWKDS-AYPEELSRVTASGFPVILS--APWYLDL------------ISYGQDWRKYYKVEP-LDFGGTQKQKQLFIGGEACLWGEYVDATNLTPRLWPRASAVGERLWSSKDVR-----DMDDAYDRLTRHRCRMVERGIAAQPLYAGYCNHENM---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BJ34-1", "uniprot_id": "A0A8M2BJ34_DANRE", "id": "A0A8M2BJ34-1", "name": "Beta-hexosaminidase", "aln": "----------------------------MLCLL-----------------------------------KFTPLFLVVAVCHGWLFGDLFEKQKELDEISLWPLPQKYQSSAVAFKLSAASFQIVHAKQSTAGPSCSLLENAFRRYFEYMFGELKRQEKSRKKAFDSDLSELQVWITS------------------------------ADPECDGYPSLRTDESYSLSVDETSA-----VLKAANVWGALRGLETFSQLVYEDDYG--VRNINKTDISDFPRFAHRGILLDSSRHFLPLKVILANLEAMAMNKFNVFHWHIVDDPSFPFMSRTFPELSQKGAYHPFTHVYTPSDVKMVIEFARMRGIRVVAEFDTPGHTQS-WGNGIK---DLLTPCYSGS-----SPSGSFGPVNPILNSSYEFMAQLFKEIS-TVFPDAYIHLGGDEVDFSCWKSNPDIQKFMNQQGFGTDYSKLESFYIQRLLDIVAATKKGY-------------MVWQEVFDN-----GVKLKADTQIHVWKGRPQYQDEMAKVTAAGFSALLS--TPWYLNR------------VSYGQDWVDIYKADP-QNFNGTDAQKKLVIGGEACLWGEYVDATNLTPRLWPRASAVAERLWSDASVT-----DVGNAYTRLAQHRCRMVRRGIPAEPLFVGHCRHEYKGL-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** * . . : . .**:* * : * :** :.:.*: :*: . : : * * : **:::*::*:: .:: * .: .*. *:* :***:.* *** **: *:* ..*: * : ::.:: *:::: *:* *.*. . * :: * . * ::* : * .: :: : * :*:***** ** . . : :: . : . :* . : : :. * : *: :.* . **: : * *. :. .:*.* .:* * :* * *:***:.* .**:*: . *: .* *:: *: *:.: * . ", "identical_positions": 82, "similar_positions": 116, "identity": "11.47%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2341", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V8B3-1", "uniprot_id": "MED24_RAT", "id": "Q4V8B3-1", "name": "Mediator of RNA polymerase II transcription subunit 24", "aln": "MKVVN-LKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLQEGLEAGSAVTGEKQLALCLQCLEKTLSSTKNRALLHIAKLEEASSWTAIEHCLLKLGEILAN----LSNPQLRSQAEHCGTLIRSIPTMLSVHSEQLHKTGFPTIHALILLEGTMNLTGEMQPLVEQLMMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTQELKWTAFTYLKIPQVLVKLKKYF--HGDK----DFTEDVNCAFEFLLKLTPLLDKADQRCNCDCTNFLLQECNKQGLLSEASFASLVSKRTADRD--PQLKSSENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTHGSGESTKTASVRALLFDISFLMLCHVAQTYGSEVILSESSSGEEVPFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNN--SSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLYSENT--LQFYNERVVIMNSILEHMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLEKGWVDSRSIHILDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVQLLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSS-HKGQASSRQKKRHREDIEDYISLFPVEDMQPSKLMRLLSSNEDDASILSSPTDRSMNSSLSASQLHT--VNMRDPLNRVLANLFLLISSVLGSRTAGPHTQFVQWFMEECVDCLEQDSRGSILQFMPFTTVSELVKVSAMSSPKV--VLAITDLSLPLGRQVAAKAIAAL------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99K74-1", "uniprot_id": "MED24_MOUSE", "id": "Q99K74-1", "name": "Mediator of RNA polymerase II transcription subunit 24", "aln": "MKVVN-LKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSCSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLQEGLEAGTPAPGEKQLALCLQCLEKTLSSTKNRALLHIAKLEEASSWTAIEHSLLKLGEILAN----LSNPQLRSQAERCGTLIRSIPSMLSVHSEQLHKTGFPTIHALILLEGTMNLTGEMQPLVEQLMMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTQELKWTAFTYLKIPQVLVKLKKYF--HGEK----DFTEDVNCAFEFLLKLTPLLDKADQRCNCDCTNFLLQECNKQGLLSEVNFASLVGKRTADRD--PQLKSSENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTHGSGESTKTASVRALLFDISFLMLCHVAQTYGSEVILSESSSGEEVPFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNN--SSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLYSENT--LQFYNERVVIMNSILEHMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLEKGWVDSRSIHILDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVQLLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSS-HKGQASSRQKKRHREDIEDYVSLFPVEDMQPSKLMRLLSSSDDDANILSSPTDRSMNSSLSASQLHT--VNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVGCLEQDSRGSILQFMPFTTVSELVKVSAMSSPKV--VLAITDLSLPLGRQVAAKAIAAL------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75448-1", "uniprot_id": "MED24_HUMAN", "id": "O75448-1", "name": "Mediator of RNA polymerase II transcription subunit 24", "aln": "MKVVN-LKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHIAKLEEASSWTAIEHSLLKLGEILAN----LSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTGFPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYS--HGDK----DFTEDVNCAFEFLLKLTPLLDKADQRCNCDCTNFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSEESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNN--SSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENT--LQFYNERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSS-HKGQASTRQKKRHREDIEDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPTDRSMSSSLSASQLHT--VNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSAMSSPKV--VLAITDLSLPLGRQVAAKAIAAL------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2PW47-1", "uniprot_id": "MED24_DANRE", "id": "Q2PW47-1", "name": "Mediator of RNA polymerase II transcription subunit 24", "aln": "MKVVN-LKQAILQAWKERWSDYQWAINIKKNCPKGATWDYLNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLTAISKFDDFSRELCVKSLLEIMDMFSNRLSCHGKAEECIGLCRAMLCTVVWLLQGCAWYCERLRD---PNDFSALESSLRACLERMANLLHSTKNRALVHIARLEEQASWTNVEQAVLKLTENLSA----VTNPTLKESLEECVSLVKSIPQMLCLQCDPPVHTTFPSVHAFIMLEGTMNLTGETQPLVEQLMMIKRMQRIPAPLFVLEIWKACFTGLIESPEGNEELKWTAFTFLKIPQVLLRLKKYP--QGEKT--QDFTEDVNVAFEYLLNLTPLLDKADQRCNCDCLSLLLQECNKLGLLSEANTATLTAKRSEDREHAPRLKTAENANIQPNPGLILRAEPTVTNILKTVDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIKLNEFPKHISGEGSKSASVRALLFDISFLMLCHVVQTYGSEVILSDPSPSSETPFFETWLQTCMPEEGKTLNPDHPCFRPESGKVESLVALLNS--SSEMKLVQMKWHEICLSTPAAILEVLNAWENGVLSVEAVQKITDNIKGKVCSMAICAVAWLVAHVRMLGLDEREKPQTMIRQLMTPMSGENT--LQFYHERVVIMSSILEHMCADVFQQTGLSLRPAVEGQEPIPYRNLLPARLPIRQALQSQFRKVLEKGWVDSHAFHLFENLLHMGGVFWFTNNLVKELLKETRKEWASRVVELLYSIFCLDTQQITLTLLGHILPRLLTDPAHWHSLADPPGRALAKLSVWCALSSYSSHHKGQASARQRKRHREDIEDYTSLFPLDDTQPSKLMRLLSSNEDENSMLSSPGDRSISSSLSASQLHT--VNMRDPLNRVLANLFLLISSQLGSKTAGPHTQFVQSFVEECVDCSEQGSRSSILQFMPFTMISELVKLQSLAKPKT--VLSITDLSLPLGRRMAAKAIAAL------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSF2-1", "uniprot_id": "MED24_DROME", "id": "Q9VSF2-1", "name": "Mediator of RNA polymerase II transcription subunit 24", "aln": "MKENNKILQLIYVAWRERWTDSQWGINIKKVLPRGVSGDVYNLADCLMQQALIGSTANPLVLNYLKHSLCAHLVSHAAVIRCIAKYDKLERVYCITALLEFLASIVDGVTCRIKSEEAV-LPSSVVHLVYWLLQIFARTVQHYELYGEISAEQS--YMLDQTCVVIDRLSQQQFLLSMLYVGCHEELEICGRIRDKYATIKGSLTNSNFTLNAPQVEQQLQQLAFIEAKHLEMQPLNPPSTLEKISCCVQPLLAVEVLLNPCKDTSYYVAELQMLQRLKKYSNTRLFYEIIRAGFLTLSNVADTSPDTMWGAFMFFKMPHIIKQLHALQRIPGEQPPPADYIPELVEALELLIEDNLLLDFMDTKCSCNMIEFLLNDWTKQQLVNDVHVKKFASQREAASQLLKKCDNGQ--QTPSNINFIKRAEVPLSGVLKTLCTNKVQD---MVNVLCQVPVGNSFELILSVATVEGRLKTFVSRLIQCNENSKPVPGDLGKLCVIRSTLFDVSFLMLTSIVQTYGSDVVLSERGDS----FFEKWVRECMVERNKLKNPRQILALCDDSIVDELLLSFSKPEASQLKPNNLSWQETCLNLPGVLHHVLIAWEQETLSSADVKSILDNIKRRLFSFSVCATSFLCAYMYSVKETELLKPLNMIQQFLAPLTSEELSSQENAKERLALSYQIIRKMQHDVHPAPSTKSRLISHS--------------PLVEQFREVWRTVVDAGHLPVRAAQSLESLLLAGGAAWLSTQLVEQLLACKYTRDMSRTMDVVFAVMHLDIEKTTEALLQYVVAPLILR-RQGEDINEPQSLVLARLCVYCIISCLESRKGNGTSALTAMKKRSRSHDDEELAANAAKVRKVIGDGSDNSSDFTDTTTGAGLAALLGSTSTSELRTTPLTLREPLQTSVQHIFAVFLQFVSGDELSPKAVFVYQFISLLVECGGE-RVAPVLRLLPNGLVQQLLKVLVTDDIKVGLISRLYDLRIQAGRLSAVSDLCLWRNMQMARHSIHL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * : * * **:***:* **.**:** *:*.: * ***:.*::**:**.:.***:*.***:::.:::** ::*: .*:*:*.:.* *: :**::: : : ::*: *:**.: * ::: : ***: * :: . . . * : . . :::::. ** :.. .: *: :. * :... :. : . * :: .. ::..: :* :* : . * :* *::*::: . . :. ** :* * * : .: . : * ** ::*:*::: :*: *:: *: :: *:* *:: . *** * :*.*: .:**:: * *:.:. .: .:* : : ...: : .* :* *** .::.:***: ::: :. ::.** :: *:*::*:*:.*:. *:**:*. ::*: ** .. . : * . :*: ***:***** :.*****:*:**: . ***.*:: ** *..* ** : :. *:.*: :.. :*::* ::.*:* **. ...: .:* ***: .*: ::.* **** :: *:::**.::* *:: : * *. **:*: *: .*: : :**:.: .*:.:* ** .. . : . *: : : . : .*:: * : :: : ::.** **. *: .:*:::** . .. *.:::::::: ** :: * .** :::. *: : ..: :* . .**:*.*:* :*. .* : . :*: ::*. .* .* . . : ....* . :.. :: .* *:*:*:* :.:*:**: : ::* :: . :.. .*:: ** *:. * * : ..:*:::* :.:*:*: . *. : : ** : ** *.. :. ", "identical_positions": 235, "similar_positions": 382, "identity": "23.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-235", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CPY3-1", "uniprot_id": "CDCA5_MOUSE", "id": "Q9CPY3-1", "name": "Sororin", "aln": "MAERRTRSGGAAQRSGPRT-SLTKPSKSSKRKSGSDLPNSFSEIWPRTTPAVPVRKAIVLKKIVAHAVEVPDVHTVRRSPRISFILEKENNPPLKVPTKEDLFKTCSVPGTPSSTPVLYTQNVEPDSGEAELDSRDLEMSQKVRRSYSRLQSLG--------CASTSTPGRRSFFGFE---GPDDLPGVSPVVCSKLIETPKVPAKDLVPARTKDLVPDSTKDLVPARTLPGISPPVV-----KEKRKKK-VPEILKSELDKWAVAMNAEFEAAEQFELLIE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96FF9-1", "uniprot_id": "CDCA5_HUMAN", "id": "Q96FF9-1", "name": "Sororin", "aln": "MSGRRTRSGGAAQRSGPRAPSPTKPLRRSQRKSGSELPSILPEIWPKTPSAAAVRKPIVLKRIVAHAVEVPAVQSPRRSPRISFFLEKENEPPGRELTKEDLFKTHSVPATPTSTPVPNPE-AESSSKEGELDARDLEMSKKVRRSYSRLETLG--------SASTSTPGRRSCFGFEGLLGAEDLSGVSPVVCSKLTEVPRVCAKPWAPD----------------MTLPGISPPPE-----KQKRKKKKMPEILKTELDEWAAAMNAEFEAAEQFDLLVE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BIB1-1", "uniprot_id": "A2BIB1_DANRE", "id": "A2BIB1-1", "name": "", "aln": "MSTKTPRLTSRKSSDQIIKSNGKSPARRRSSRLSANDENLPSKVVP---PPVAMKRSITVRKIAPRKTQALSNSNKENVERISEVSTKRSKVLTSSP------AISAEPKTSVLSPILPSSSPPPQPTESEQDS---VWSKKVRRSYSRLSMGDKSFESPRPARSSSPNNRESLFGFERLQTPEVMKKTEGSRSAPLGFMSLSLGSFNLSAADES-----------ASNPPEVDPNIPGVCLGKKTTRRKRVQQIKMSELDVLAAKMNAEFEEAESFELFVE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : .* . . . . ..* : . : .:: . .:: * ....:::.*.:::*..: .:. . .. *** . *..: : * *. :*: .. ... *.* *: *:*********. . . *:*. .*.* **** .: : .. .: * . .. . . * :.* *:. ::* : :* :*** *. ****** **.*:*::*", "identical_positions": 55, "similar_positions": 89, "identity": "19.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2360", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q10472-1", "uniprot_id": "GALT1_HUMAN", "id": "Q10472-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 1", "aln": "---------MR---KFAYCKVVLATSLIWVLLDMFLLLYFSECN-----KCDEKKE----------------------------------------RGLPAGDV--------------LEPVQKPHEGPGEMGKPVVIPKEDQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDNLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEEIVLVDDASERDFLKRPLESYVKKLKVPVHVIRMEQRSGLIRARLKGAAVSKGQVITFLDAHCECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRVGLRHKLQCKPFSWYLENIYPDSQIPRHYFSLGEIRNVETNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIRTDDLCLDVSKLNGPVTMLKCHHLKGNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRDCNGSRSQQWLLRNVTLPEIF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q10473-1", "uniprot_id": "GALT1_RAT", "id": "Q10473-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 1", "aln": "---------MR---KFAYCKVVLATSLVWVLLDMFLLLYFSECN-----KCEEKKE----------------------------------------RGLPAGDV--------------LELVQKPHEGPGEMGKPVVIPKEDQEKMKEMFKINQFNLMASEMIAFNRSLPDVRLEGCKTKVYPDSLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEEIVLVDDASERDFLKRPLESYVKKLKVPVHVIRMEQRSGLIRARLKGAAVSKGQVITFLDAHCECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRVGLRHKLQCKPFSWYLENIYPDSQIPRHYFSLGEIRNVETNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIRTDDLCLDVSKLNGPVTMLKCHHLKGNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRDCTGSRSQQWLLRNVTLPEIF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08912-1", "uniprot_id": "GALT1_MOUSE", "id": "O08912-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 1", "aln": "---------MR---KFAYCKVVLATSLVWVLLDMFLLLYFSECN-----KCEEKQE----------------------------------------RGLPAGDV--------------LELVQKPHEGPGEMGKPVVIPKEDQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDNLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEEIVLVDDASERDFLKRPLESYVKKLKVPVHVIRMEQRSGLIRARLKGAAVSRGQVITFLDAHCECTAGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRLGLRRKLQCKPFSWYLENIYPDSQIPRHYFSLGEIRNVETNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIRTDDLCLDVSKLNGPVTMLKCHHLKGNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRDCTGSRSQQWLLRNVTLPEIF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FDA0-1", "uniprot_id": "E7FDA0_DANRE", "id": "E7FDA0-1", "name": "Polypeptide N-acetylgalactosaminyltransferase", "aln": "---------MR---KFAYCKVVLATSLVWVMLDMFILLYFSECN-----KCDDKKE----------------------------------------RGLPGRD----------------TVVQRPHDGPGEMGKPVVIAKDQQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDDLPRTSVVIVFHNEAWTTLLRTVHSVIDRSPRHLLEEIVLVDDASERDFLKRQLEHYVRKLEVPVRVVRMEQRSGLIRARLKGASISTGQVITFLDAHCECTTGWLEPLLSRIKLDKKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISTRTSLRQRLQCKPFSWYLENVYPDSQIPRHYYSLGEIRNVETNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIRTDDLCLDVSKLNGPVMMLKCHHLKGNQLWEYDPVKLSLVHVNSNQCLDKASEDDSQVPSVRDCSGARSQQWLLRNVTLPEIF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6WV17-1", "uniprot_id": "GALT5_DROME", "id": "Q6WV17-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 5", "aln": "MTFSTFTRKMRGRMRSNTCRIVLLTSLVWVIFDFVLIARYSDCIGKDGWRCKRSGEYDVELPNAERLVDDNQLVDDNEINTEKSLDGESGGALIMGQGFASGGISMTYPSVVLKKWFLAPSVQEAKGKPGEMGKPVKIPADMKDLMKEKFKENQFNLLASDMISLNRSLTDVRHEGCRRKHYASKLPTTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDDASERDFLGKQLEEYVAKLPVKTFVLRTEKRSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISDETFEYITASDSTWGGFNWKLNFRWYRVPSREMARRNNDRTAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMDIWGGENLEMSFRIWQCGGILEIIPCSHVGHVFRDKSPYTFPGGVAKIVLHNAARVAEVWLDEWRDFYYSMSTGARKASAGDVSDRKALRDRLKCKSFRWYLENVYPESLMPLDYYYLGEIRNAETETCLDTMGRKYNEKVGISYCHGLGGNQVFAYTKRQQIMSDDLCLDASSSNGPVNMVRCHNMGGNQEWVYDAEEKWIRHTNTGQCLQRATRDDANTPLLRPCSYGKGQQWLMESKFKWQAH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : *::** ***:**::*:.:: :*:* :*. . * :*:.. . **..: ******** *. : :: *** ** *****:**:**::****.*** ***: * *...** **:*********:****** ***:**** :::**:*********** : ** ** ** * . *:* *:********* ** *:************ *******:** :::************:****::.** *:************ **.*** **:.*** *:*************:*** ***:** ***********:********* ***:.*********. :*******..:*: :* *:****:**:::*:* :*.*. *.. **:* * .** :*:**.* *****:**:* :* .*: ******.**: ***.*.** ****** ***:******:** .::* :******.*. **** *::**:: *** * **. : : *.*:.***::*:.:*::.* :* *. .:.****:.. : .", "identical_positions": 337, "similar_positions": 134, "identity": "53.49%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2365", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q13371-1", "uniprot_id": "PHLP_HUMAN", "id": "Q13371-1", "name": "Phosducin-like protein", "aln": "MTTLDDKLLGEKLQYYYSSSEDEDSDHE-DKDRGRCAPASSSVPAEAELAGEGISVNTGPKGVINDWRRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQKSIVIMVHIYEDGIPGTEAMNGCMICLAAEYPAVKFCKVKSSVIGASSQFTRNALPALLIYKGGELIGNFVRVTDQLGDDFFAVDLEAFLQEFGLLPEK--EVLVLTSVRNSATCHSEDSD--LEID", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DBX2-1", "uniprot_id": "PHLP_MOUSE", "id": "Q9DBX2-1", "name": "Phosducin-like protein", "aln": "MTTLDDKLLGEKLQYYYSTSEDEDSDHE-DKDRGRGAPAISSTPAEAELAGEGISINTGPKGVINDWRRFKQLETEQREEQCREMERLIKKLSMSCRSHLDEEEEQQKQKDLQEKISGKMTLKEFGTKDKNLDDEEFLQQYRKQRMEEMRQQFHKGPQFKQVFEIPSGEGFLDMIDKEQKSTLIMVHIYEDGVPGTEAMNGCMICLATEYPAVKFCRVRSSVIGASSRFTRNALPALLIYKAGELIGNFVRVTDQLGEDFFAVDLEAFLQEFGLLPEK--EVLVLTSVRNSATCHSEDSD--LEID", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QTL0-1", "uniprot_id": "F1QTL0_DANRE", "id": "F1QTL0-1", "name": "", "aln": "MTTLDDKILGEKLQYYYSSSEDEESDHEEDENAHKTIRDQEVLDVELDYSADGSSVNTGPKGVINDWRKYKQLENEQRIEQQKEMEKLIKKLSMTCKSHLEEEADKQKQKELQDKLTGKLNLRVDEEEEEDDDDEAFLQQYRLQRMEQMRRQLCGGRRFEKVMDISSGEEFLRAVDEEGKSTLVLVHIYEPEVPACQAMDGSLLCLALQYPMVKFCRVRGSAVGTSALFRSSALPALLLYRGGDLVGNLVRVSDQLGDDFYATDVEALLQEYGLLPEKYAQPNTHSSIRNAAVTHPDDSDSDLDID", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******:**********:****:**** *:: : . .* : :.:* *:************::****.*** ** :***:*******:*:***:** ::****:**:*::**:.*: ::: *** ****** ****:**:*: * :*::*::*.*** ** :*:* ** :::***** :*. :**:*.::*** :** ****:*:.*.:*:*: * .******:*:.*:*:**:***:****:**:*.*:**:***:****** : . :*:**:*. *.:*** *:**", "identical_positions": 172, "similar_positions": 85, "identity": "56.21%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2374", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66K64-1", "uniprot_id": "DCA15_HUMAN", "id": "Q66K64-1", "name": "DDB1- and CUL4-associated factor 15", "aln": "MAPSSKSERNSGAGSGGGGPGGAGGKRAAGRRREHVLKQLERVKISGQLSPRLFRKLPPRVCVSLKNIVDEDFLYAGHIFLGFSKCGRYVLSYTSSSG-DDDFSFYIYHLYWWEFNVHSKLKLVRQVRLFQDEEIYSDLYLTVCEWPSDASKVIVFGFNTRSANGMLMNMMMMSDENHRDIYVSTVAVPPPGRCAACQDASRAHPGDPNAQCLRHGFMLHTKYQVVYPFPTFQPAFQLKKDQVVLLNTSYSLVACAVSVHSAG---DRSFCQILYDHSTCPLAPASPPE-PQSPELPPALPSFCP----EAAPARSSGSPEPSPAIAKAKEFVADIFRR----AKEAKGGVPEEAR-----------------PALCPGPSGSR-------------CRAHSEPLALCGETAP--RDSPPASEAPASEPGYVNYTKLYYVLESGEGTEPEDELEDDKISLPFVVTDLRGRNLRPMRERTAVQGQYLTVEQLTLDFEYVINEVIRHDATWGHQFCSFSDYDIVILEVCPETNQVLINIGLLLLAFPSPTEEGQLRPKTYHTSLKVAWDLNTGIFETVSVGDLTEVKGQTSGSVWSSYRKSCVDMVMKWLVPESSGRYVNRMTNEALHKGCSLKVLADSERYTWIVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PFH3-1", "uniprot_id": "DCA15_MOUSE", "id": "Q6PFH3-1", "name": "DDB1- and CUL4-associated factor 15", "aln": "MAPSSKSERNSGAGSAGGGPGGTGGKRAVGRRREHVLKQLERVKISGQLSPRLFRKLPPRVCVSLKNIVDEDFLYAGHIFLGFSKCGRYVLSYTSSSG-DDDFSFYIYHLYWWEFNVHSKLKLVRQVRLFQDEEIYSDLYLTVCEWPSDASKVIVFGFNTRSANGMLMNMMMMSDENHRDIYISTVAVPPRGRCAACQDASRAHPGDPSAQCLRHGFMLHTKYQVVYPFPTFQPAFQLKKDQVVLLNTSYSLVACAVSVHSAG---DSSFCQILYDHTALPPAPPSSPG-PWSPEAAPAFPSLGV----EVVPAQPSGAPEPSPAIAKAKEFVADIFRR----AKEAKGSPLEETR-----------------LPSSLGPSSSR-------------CRPSLEPQAPSGEVVP--RDSPPAAETTAPEPGYINYTKLHYVLQSGEGTEPEDEFEDDKISLPFVVTDLRGRNLRPMRERTDMQGQYLTVEQLTLDFEYVINEVIRHDATWGHQFCSFSDYDIVILEVCPETNQVLINIGLLLLAFPAPTEEGQLRPKTYHTSLKVAWDLNTGIFETVSVGDLTEVKGQTSGSVWSSYRKSCVDMVMKWLVPESSGRYVNRMTNEALHKGCSLKVLADSERYTWIVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F3Z0-1", "uniprot_id": "E7F3Z0_DANRE", "id": "E7F3Z0-1", "name": "", "aln": "MAPSSKSEKDDNK------------QKQPKKHKEHIIKLLTRGRLNGQLSQRLFRKLPPRVCVPLKTIVSEEFLRAGHIFLGFTKCGRYVLSYTSDCGEDDDFSFYTYHLYWWEFNLHSRLKQVHHVRLFAGEDIYSDLYLTVCEWHNDHSKLVIFGFNTRSSSSALMN-MMMSDENNRDIYITITSMPPAQPCKQCCPVASSSTIRTGGECLEHGYVLNARYQVVYPFPTFQPALQLKKDQVILLNTSYSLVACAISLCTGDGQQESQNNQILYRKREPSSSSTSAPAGPTSPFSSSSASSQGSPDLRHSKPHVTPLSPSQSQAAVWAREFAADIFRRAQAGAREAERCKTKEKEETDTQRRLHDEERTRESPREVPGPSSSSSEPNQSSVVESGVCNAIVSPRSTSSVSSPSPHEQEPSSSSSSSEPAYVNYTTLRYRLPQATSVEQSNGEEDDKVQLPFTVTDLKGRPLQIVTG--QYSGQFVCIEQLTLDFEYLINEVIRNDAEWGSQFCSFSDYDVVILEVCPETNIVVINIGLLLLAFSN-CDDEHCRPKSYHSSLQVSWDLNTGACHTVGVGDLTEVKGQTSGSVWSSYRKSCVNTVMRWLVPESSSRYINRMTNEALHKGSSLQVLTDNDRGTWIVL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********::.. :: :::**::* * * ::.**** ************.**.**.*:** ********:***********..* ******* *********:**:** *::**** .*:************ .* **:::*******:.. *** *******:****:: .::** * * .: : . ...:**.**::*:::*************:*******:************:*: :.. : . **** : . :..*.* * ** ..: .* . * .. :*. * * . *:**.****** *:**: :* . ***.* *.. .* : .. * ::. *::.:.:.**.*:***.* * * .. ..* .: ****:.***.****:** *: : .**:: :*********:******:** ** *********:********** *:**********. :: : ***:**:**:*:****** .**.************************: **:*******.**:***********.**:**:*.:* *****", "identical_positions": 343, "similar_positions": 144, "identity": "53.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2376", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P13098-1", "uniprot_id": "ESM8_DROME", "id": "P13098-1", "name": "Enhancer of split m8 protein", "aln": "---------MEYTTKTQIYQKVKKPMLERQRRARMNKCLDNLKTLVAELRG--DDGILRMDKAEMLESAVIFMRQQKTPKKVAQ------------EEQSLPLDSFKNGYMNAVNEVSRVMASTPG-----------MS---VDLGKSVMTHLGRVYKNLQQF----------------------HEAQSAADFIQNSMDCSSMDKAP------LSPASSGYHSDCDSP--APSPQPMQQPLWRPW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13096-1", "uniprot_id": "ESM5_DROME", "id": "P13096-1", "name": "Enhancer of split m5 protein", "aln": "-MAPQSNNSTTFVSKTQHYLKVKKPLLERQRRARMNKCLDTLKTLVAEFQG--DDAILRMDKAEMLEAALVFMRKQVVKQQAP--------------VSPLPMDSFKNGYMNAVSEISRVMACTPA-----------MS---VDVGKTVMTHLGVEFQRMLQ-----------------------------ADQVQTSVTTS--TPRP------LSPASSGYHSDNEDSQSAASPKPVEETMWRPW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q01069-1", "uniprot_id": "ESMB_DROME", "id": "Q01069-1", "name": "Enhancer of split mbeta protein", "aln": "------MVLEMEMSKTYQYRKVMKPMLERKRRARINKCLDELKDIMVECLTQEGEHITRLEKADILELTVEHMKKLRAQKQLRLSSVTGGV-SPSADPKLSIAESFRAGYVHAANEVSKTLAAVPG-----------VS---VDLGTQLMSHLGHRLNYLQ------------VVVP--SLPIGVPLQ---APVEDQAMVTPP---PS-----ECDSLESGACSPAPSEASS--TSG---PMWRPW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q01068-1", "uniprot_id": "ESM3_DROME", "id": "Q01068-1", "name": "Enhancer of split m3 protein", "aln": "--------MVMEMSKTYQYRKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLKQRGGLSLQGVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVLLQTQQTDEIGRKIMKFLSTRLIELQTQLLQQQQQQQQHQQ------------QQIPQSSGRLAFPLLGGYGPAAAAAAISYSSFLTSKDELIDVTSVDGNALSETASVSSQ--ESGASEPVWRPW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q01070-1", "uniprot_id": "ESMC_DROME", "id": "Q01070-1", "name": "Enhancer of split mgamma protein", "aln": "----MSSLQMSEMSKTYQYRKVMKPMLERKRRARINKCLDELKDLMVATLESEGEHVTRLEKADILELTVTHLQKMKQQRQHKR---------ASGDESLTPAEGFRSGYIHAVNEVSRSLSQLPG-----------MN---VSLGTQLMTHLGQRLNQIQPAE---------KEVLPVTAPLSVHIANRDAYSVPISPISSYAGSPN-----SNTSSTSHSLLTTIDVTKMEDDSEDEENVWRPW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13097-1", "uniprot_id": "ESM7_DROME", "id": "P13097-1", "name": "Enhancer of split m7 protein", "aln": "------MATKYEMSKTYQYRKVMKPLLERKRRARINKCLDELKDLMAECVAQTGD--AKFEKADILEVTVQHLRKLKESK---------------KHVPANPEQSFRAGYIRAANEVSRALASLPR-----------VD---VAFGTTLMTHLGMRLNQLE-------------QPMEQPQAVNTPLSIVCGSSSSSSTYSSASSCSS------ISPVSSGYASDNESLLQIS-SPG---QVWRPW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q01071-1", "uniprot_id": "ESMD_DROME", "id": "Q01071-1", "name": "Enhancer of split mdelta protein", "aln": "----MAVQGQRFMTKTQHYRKVTKPLLERKRRARMNLYLDELKDLIVDTMDAQGEQVSKLEKADILELTVNYLKAQQQQRVANP---------QSPPPDQVNLDKFRAGYTQAAYEVSHIFSTVPG-----------LD---LKFGTHLMKQLGHQLKDMK---------------------------------QEEEIIDMAEEPVN------LADQKRSKSPREEDIHHG-------EEVWRPW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "F1QI81-1", "uniprot_id": "F1QI81_DANRE", "id": "F1QI81-1", "name": "", "aln": "MTASNMGNGPEKNFNAKEERKLRKPLIEKKRRERINSSLEQLKGIMVDAYN---LDQSKLEKADVLEITVQHMENLQRGHGQGG--------SNSPGTGFESRQRYSSGYIQCMHEVHNLLLSCPG--------MD------KTLGARLLNHLLKSLPHISTEPSGTSSAGTSSPLPLSPTQSPINLPSSLQPHALLLSPSPPSSPTHSLVRPREQSSPPSSPSPQSPASLPPFFPGVDPSMWRPW", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: *: **::*::** *:* *: ** ::. :::**::** :: .:. : : ** .. :: . : . :: : :****", "identical_positions": 21, "similar_positions": 35, "identity": "8.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2378", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35147-1", "uniprot_id": "BAD_RAT", "id": "O35147-1", "name": "Bcl2-associated agonist of cell death", "aln": "MGTPKQPSLAPAHALGLRKSDPGIRSLGSDAGGRRWRPAAQSMFQIPEFEPSEQEDASTTDRGLGPSLTEDQPG-----PYLAPGLLGSIVQQQPGQAANNSHHGGAGTMETRSRHSSYPAGTEEDEGMEEELSPFRGRSRSAPPNLWAAQRYGRELRRMSDEFEGSFK-GLPRPKSAGTATQMRQSASWTRIIQSWWDRNLGKGGSTPSQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61337-1", "uniprot_id": "BAD_MOUSE", "id": "Q61337-1", "name": "Bcl2-associated agonist of cell death", "aln": "MGTPKQPSLAPAHALGLRKSDPGIRSLGSDAGGRRWRPAAQSMFQIPEFEPSEQEDASATDRGLGPSLTEDQPG-----PYLAPGLLGSNIHQQ-GRAATNSHHGGAGAMETRSRHSSYPAGTEEDEGMEEELSPFRGRSRSAPPNLWAAQRYGRELRRMSDEFEGSFK-GLPRPKSAGTATQMRQSAGWTRIIQSWWDRNLGKGGSTPSQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92934-1", "uniprot_id": "BAD_HUMAN", "id": "Q92934-1", "name": "Bcl2-associated agonist of cell death", "aln": "------------------------------------------MFQIPEFEPSEQEDSSSAERGLGPSPAGDGPSGSGKHHRQAPGLLWDASHQQ-EQPTSSSHHGGAGAVEIRSRHSSYPAGTEDDEGMGEEPSPFRGRSRSAPPNLWAAQRYGRELRRMSDEFVDSFKKGLPRPKSAGTATQMRQSSSWTRVFQSWWDRNLGRGSSAPSQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B8K5-1", "uniprot_id": "A0A8M2B8K5_DANRE", "id": "A0A8M2B8K5-1", "name": "", "aln": "---------------------------------------------MENTSHDHQDDSSTLDEKERSHLKGTIKN-----HGQHQDRTSANISPQ-GRVRLYSESQVYTVSRWQDTETQDGASMEENG----DGLPFRGRSQSAPAALWKAKKYGRQLRRMSDEFDTWLDKGEVKRANS-------QKQTYRGWFSFLWSPKEEEGRE----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . ..*:*:*: :. . . . * : *. . . :. .:. *. *:: : ******:***. ** *::***:******** :. * : .: *. : :. *. : .* . ", "identical_positions": 34, "similar_positions": 44, "identity": "16.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2390", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IUX7-1", "uniprot_id": "AEBP1_HUMAN", "id": "Q8IUX7-1", "name": "Adipocyte enhancer-binding protein 1", "aln": "MAAVRGAPLLSCLLALLALCPGGRPQTVLTDDEIEEFLEGFLSELEPE--PREDDVEAPPPPEPTPRVRKAQAGGKPGKRPGTAAEVPPEKTKDKGKKGKKDKGPKVPKESLEGSPRPPKKGKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPPSGKRPPILAPSETLEWPLPPPPSPGPEELPQEGGAPLSNNWQNPGEETHVEAREHQPEPEEETEQPTLDYNDQIEREDYEDFEYIRRQKQPRPPPSRRRRPERVWPEPPEEKAPAPAPEERIEPPVKPLLPPLPPDYGDGYVIPNYDDMDYYFGPPPPQKPDAERQTDEEKEELKKPKKEDSSPKEE-TDKWAVEKGKDHKEPRKGEELEEEWTPTEKVKCPPIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDDARTQWIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMYTNGYEEMTFHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSVAPVYSYYAQNEVVATDDLDFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFRYTAGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAAQMGSEFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPDATVSTEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTP---TQEQLLAAAMAAARGEDEDEVSEAQ--------ETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYTGGMGIVNGAKWNPRTGTINDFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDEQGIPIANATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGYTPSAKTCNVDYDIGATQCNFILARSNWKRIREIMAMNGNRPIPHIDPSRPMTPQQRRLQQ----RRLQHRLRLRAQMRLRRLNATTTLGPHTVP-PTLPPAPATTLSTTIEPWGLIPPTTAGWEESETETYTEVVTEFGTEVEPEFGTKVEPEFETQLEPEFETQLEPEFEEEEEEEKEEEIATGQAFPFTTVETYTVNFGDF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q640N1-1", "uniprot_id": "AEBP1_MOUSE", "id": "Q640N1-1", "name": "Adipocyte enhancer-binding protein 1", "aln": "MAPVRTASLLCGLLALLTLCPEGNPQTVLTDDEIEEFLEGFLSELETQSPPREDDVEVQPLPEPTQRPRKSKAGGKQR----ADVEVPPEKNKDKEKKGKKDKGPKATKP-LEGSTRPTKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKRPSAGKKFSTVAPLETLDRLLPSPSNPSAQELPQKRDTPFPNAWQGQGEETQVEAKQPRPEPEEETEMPTLDYNDQIEKEDYEDFEYIRRQKQPRPTPSRRR----LWPERPEEKTEEPEERKEVEPPLKPLLP---PDYGDSYVIPNYDDLDYYFPHPPPQKPDVGQEVDEEKEEMKKPKKEGSSPKEDTEDKWTVEKNKDHKGPRKGEELEEEWAPVEKIKCPPIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQAGANEDDYYDGAWCAEDESQTQWIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMYTNGYEEMTFYGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCPVTPVYSYYAQNEVVTTDSLDFRHHSYKDMRQLMKAVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGDHELGEPEFRYTAGIHGNEVLGRELLLLLMQYLCQEYRDGNPRVRNLVQDTRIHLVPSLNPDGYEVAAQMGSEFGNWALGLWTEEGFDIFEDFPDLNSVLWAAEEKKWVPYRVPNNNLPIPERYLSPDATVSTEVRAIISWMEKNPFVLGANLNGGERLVSYPYDMARTP---SQEQLLAEALAAARGEDDDGVSEAQ--------ETPDHAIFRWLAISFASAHLTMTEPYRGGCQAQDYTSGMGIVNGAKWNPRSGTFNDFSYLHTNCLELSVYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDEQGIPIANATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGYTSSAKICNVDYDIGATQCNFILARSNWKRIREILAMNGNRPILRVDPSRPMTPQQRRMQQ----RRLQYRLRMREQMRLRRLNS--TAGPATSPTPALMPPPSPTPAITLRPWEVLPTTTAGWEESETETYTEVVTEF--------------------ETEYGTDLEVEEIEEEEEEEEEEMDTGLTFPLTTVETYTVNFGDF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F829-1", "uniprot_id": "E7F829_DANRE", "id": "E7F829-1", "name": "Adipocyte enhancer-binding protein 1", "aln": "-MRVLVCAALFALCWILTFAIN--------------------EELANAPNQRTRSIQMRQSNGVKSNRDDLQEGFSEDTQMDEPGEEMAEKEKPKGKKTPEEILAAKAKKAAEKEAKAKKPKPTKKPKPTKKP--KPPKATKKSK--PPKATKKPKAAKPTTPARETKPTKKPTME--EEEEKLLLELGWDTLSPKETEMEKPIG-----PDHDMHSKKDPTTPPSVKEHMPDNWDSRHEIQEPD-----LIPKVKQPSSTD--------------DPSIYLPIPEEATTTPRT--------------IAPWYEEYDY-----------ADLAAKKQEEELEKARKAKEEKAEKLRKMWEEEE----EEKRKQTALHAEPK-----KCPPLGLESHRVEDDQILASSSSNLGYSALRGRLNMQNSADEEDVYGGAWCADTEEKEHWFQVDGRREVEFTGVITQGRNSESNNDFVSSFFVAFSNDSREWTVLHDGYAEWLFYGNVDKDTPVMTEFSYPVVARYIRVLPQSWNGSLCMRLEVLGCQLP--TSYATENDVPPTDDLDYRHHNYKEMRQMMKVINEECPNITRIYNIGKSFQGLKMYAMEISDNPGEHEPGEPEFRYTAGLHGNEVLGRELLLLLMQFICKEYNDDNPRVHRLVETVRIHLVPSLNPDAYELAYEMGSEMGNWALGHWTEEGYDIFQNFPDLNSVLWGAEDRGWVPRIVPNHHIPIPENFLN--GSVATETKAIISWMERTPFVLGANLQGGEKLVAYPFDMQRPPRATSTDGRVGQPVQEYHNMNEETWARIQRQNEGALRETADENLFRWLATTYAHSHLTLTENHRGSCHTDDITGGQGIINRASWKPVVGSMNDFSYLHTNCFEISIFLGCDKFPHESELPSEWENNREALLAFIEQVHRGIKGVVRDVDGNLLANATVSVEGIKHDVKTASTGDYWRLLNPGEYRVTARADGYSSQTRLCIVGYDANATPCSFTLTKSNWARIQQILAQSGKRPRLVNNIPRNANNQVNGGSTGPAGGSQNERLNRIRLMRMRKLRMERMKSSTTTEMTTSTTTTTPEPTTTTT-LGSTSESWYDWFEQESFNFEHTIDED-----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .. * * :*::. .** * .:: . . . : * . * .** * * ** :: . .* * ..:. * * **.**** ********.* ********* *.:. : . .: . : * : * . : *: ..: : : * . :* . * ..:*:. * * : *** .. : . * .: .* . : * *:: ** . ..:::**::*.:* .. *. . * *: : ** *. * ****:*:****:**:** *** . * .* ******* .* *:* *.*****: : : :*::** ** ..*********:*. ::***::***.*****: *.: :** * *:*********::*:. *****:**: * :************** :. ** ::*:* .**.**:***.**:***:**.:*****.*** *.:*** :***:**********:** **********:****************::*:**.*.****: **: .***********.**:* :****:****** *****:***::*********.**:: *** ***:::****.:*. .:*:**.:***:***:.********:***:**:**:** *.* : : :. .: :. ::: :. * **.*. :***** ::* :***:** :**.*:::* *.* **:* *.*:* *::**********:*:*.:************* *****:****:*:*********** * :* :****:**.**:*.***** *****:**********:*:**:..:: * *.** .** *.* *::*** **::*:* .*:** : .* . * . . : **. **:*:*. .. * .: ...:. : * . : .* *.*: .: ..: * ", "identical_positions": 474, "similar_positions": 266, "identity": "40.27%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2392", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80UM3-1", "uniprot_id": "NAA15_MOUSE", "id": "Q80UM3-1", "name": "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "aln": "---------MPAVS-LPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLGKKEEAYELVR---RGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQ-TSPDKVDYEYSELLLYQNQVLREAG-----LYREALEHLCTYEKQICDKLAVEETKGELLLQLCRLEDAADVYRGLQERNPGNWAYYKGLEKALKPA-NMLERLKIYEEAWTKYPRGLVPRRLPLNFLSG-EKFKECLDRFLRMNFSKGCPPVFNTLRSLYRDKEK--VAIVEELVVGYETSLKSCRLFNPNDDGK---EEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYVLKANLIKEAEEMCSKFTR--EGTSAVENLNEMQCMWFQTECAQAYKAMNK--------------------------------------FGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVDLLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQRRAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDE-EIGGPK-EELIPEKLAKVETPLEE-AIKFLTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSGHPWLHECMIRLFH-SVCESKD--LPETVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSLPHRLSAAKMVYYLDSSSQKRAIELATTLDGSLTNRNLQTCMEVLEALCDGSLG-DCKEAAEAYRASCHKLFPYALAF-----MPPGYEEDMKITVNGDSS------AETEELANEI-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZD89-1", "uniprot_id": "D3ZD89_RAT", "id": "D3ZD89-1", "name": "", "aln": "---------MPAVS-LPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLGKKEEAYELVR---RGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQ-TSPDKVDYEYSELLLYQNQVLREAG-----LYREALEHLCTYEKQICDKLAVEETKGELLLQLCRLEDAADVYRGLQERNPENWAYYKGLEKALKPA-NMLERLKIYEEAWTKFPRGLVPRRLPLNFLSG-EKFKECLDRFLRMNFSKGCPPVFNTLRSLYRDKEK--VAIVEELVVGYETSLKSCRLFNPNDDGK---EEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTR--EGTSAVENLNEMQCMWFQTECAQAYKAMNK--------------------------------------FGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVDLLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQRRAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDE-EIGGPK-EELIPEKLAKVETPLEE-AIKFLTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECMIRLFN-SVCESKD--LPEAVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSLPHRLSAAKMIYYLDSSSQKRAIELATTLDGSLTNRNLQTCMEVLEALCGGSLG-DCKEAAEAYRVSCHKLFPYALAF-----MPPGYEEDMKITVNGDSS------AETEELANEI-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BXJ9-1", "uniprot_id": "NAA15_HUMAN", "id": "Q9BXJ9-1", "name": "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "aln": "---------MPAVS-LPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLGKKEEAYELVR---RGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQ-TSPDKVDYEYSELLLYQNQVLREAG-----LYREALEHLCTYEKQICDKLAVEETKGELLLQLCRLEDAADVYRGLQERNPENWAYYKGLEKALKPA-NMLERLKIYEEAWTKYPRGLVPRRLPLNFLSG-EKFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEK--VAIIEELVVGYETSLKSCRLFNPNDDGK---EEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTR--EGTSAVENLNEMQCMWFQTECAQAYKAMNK--------------------------------------FGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVDLLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQRRAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDE-EIGGPK-EELIPEKLAKVETPLEE-AIKFLTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECMIRLFNTAVCESKD--LSDTVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSLPHRLSAAKMVYYLDPSSQKRAIELATTLDESLTNRNLQTCMEVLEALYDGSLG-DCKEAAEIYRANCHKLFPYALAF-----MPPGYEEDMKITVNGDSS------AEAEELANEI-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QE25-1", "uniprot_id": "F1QE25_DANRE", "id": "F1QE25-1", "name": "", "aln": "---------MPSIT-LPPKENALFKRILRCYEHKQYRNGLKFCKQILSNSKFAEHGETLAMKGLTLNCLGRKEEAYDLVR---RGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKIVEEFRKTQQ-TSPDKVDYEYSELLLYQNQLLREAE-----LFKEALDHLTSYEKQICDKLAVEETRGELLLKLDRAGEATEVYHRLLERNPENWSYYQGLEKALKPK-SAEDKQKIYEDAWVKYPKGLVPRRLPLSFLTG-EKFRECLDRYLRMNFSKGCPPVFTTLKSLYHHKDK--VAIIEELVVGYDKSLKTCKMFNQNDDGK---IEPPTTLLWVQYFLAQHFNHIGKHTVALEYINTAIESTPTLIELFLIKAKIYKHAGNIREAARWMDEAQALDTADRFINSKCAKYLLKAGLIKEAEEMCSKFTR--EGTSAVENLNEMQCMWFQTECALAYKSLNK--------------------------------------YGEALKKCHEIERHFVEITDDQFDFHTYCMRKMTLRSYVDLLNLEDVLRMHPFYFKAARTAIEIYLSLHDNPLSDDNKESQADNANLTDKELKKLRNKQRRAQKKAQLEEEKKNAEKEKQLKNQKKKKEEDEE-EIGGPK-EELIPEKLAKIENPLEE-AVKFLTPLKNLVKNKIETHLLAFEIYLRKEKYLLMLQSVKRAYSLDPDHPWLHQCLVRFFK-GVSDSKD--MPEAVQTVLKQEITKLFGESDPKTFNKNFLSKHANSIPHRVAAAKMMVFLDSSSEGKAAELATSLNESLTDRSLQTCAEVLQALRDGSLGSQQEKFTESYRVSCHGLYPYAVAF-----MPPGYQDNTAVTTNGDLSP-----CDHEDLPNEM-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWI2-1", "uniprot_id": "Q9VWI2_DROME", "id": "Q9VWI2-1", "name": "", "aln": "---------MPSSDPLPPKEGALFRKLLKCYELKQYKNGLKLAKQILSNPKYMEHGETLAMKGLTLNGLGRREEAYKYVR---LGLRNDLRSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWEKDNLQILKDLSLLQIQMRDLEGYKETRHHLFTLRPSQHASWIGFAMSYHLLGDYDMANSILETFSQSQ--TSIEAHDYRHSELLLYQNQILIESN-----RLQQAVDHLTKYQGQIVDKLAVRETMGDLYIKLQQQEKAVPIFESLIRRNPENVLYYEQYIAARQVT-DSSAVVSIYRVFQEQYPRALCPRRLPLNIANG-DEFRVVTDEYLRRGLRKGIPPLFVNVRTLHQIPER--AAVIEELALQYFENLTRSGHFSREDADAGIPVEPASALVWTALFLAQHYDYMRDTDRALEYINVAIDHTPTLIELLITKGRIFKHAGDPVEAYVWLEEAQSMDTADRYINSKCAKYMLRANMVQEAEEICAKFTR--EGVSAMDNLNEMQCMWFQTECALAYQRMGR--------------------------------------WGESLKKCHEVERHFAEIVEDQFDFHTYCMRKMTLRAYVGLLRLEDVLRQHPFYFKAAKCAIEVYIRLYDKPLKSETTIEEIDIENLPPSELKKLRSKQRKAKKKAELESAQAAQAQVKREQHQKSKQQANQETDPDAPQLDELVAEKLERTDDPLDK-AIEFLKPLQQLAKERIETHLLAFELYYRKNKLLLMLQCIRRARAVDASHPVIHSCIIRFVKSLTSAAKEQPFNEHVQQVLEKATKELIGSKTPQQLNDEFIAKHNASILHLYEGARSLYELDNSKKAAAIKLVTSFN--LAKLRLEEATKIYTALRDGDVFGECEAEAASYQQACHQRFQYARIFRNVEELEAQLQEKEAAKLRAEEEQQQLIHVDSSEPVSVLATAAAAS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12945-1", "uniprot_id": "NAT1_YEAST", "id": "P12945-1", "name": "N-terminal acetyltransferase A complex subunit NAT1", "aln": "MSRKRSTKPKPAAKIALKKENDQFLEALKLYEGKQYKKSLKLLDAILK--KDGSHVDSLALKGLDLYSVGEKDDAASYVANAIRKIEGASASPICCHVLGIYMRNTKEYKESIKWFTAALNNGSTNKQIYRDLATLQSQIGDFKNALVSRKKYWEAFLGYRANWTSLAVAQDVNGERQQAINTLSQFEKLAEGKISDSEKYEHSECLMYKNDIMYKAASDNQDKLQNVLKHLNDIEPCVFDKFGLLERKATIYMKLGQLKDASIVYRTLIKRNPDNFKYYKLLEVSLGIQGDNKLKKALYGKLEQFYPRCEPPKFIPLTFLQDKEELSKKLREYVLPQLERGVPATFSNVKPLYQRRKSKVSPLLEKIVLDYLSGLDPT--------------QDPIPFIWTNYYLSQHFLFLKDFPKAQEYIDAALDHTPTLVEFYILKARILKHLGLMDTAAGILEEGRQLDLQDRFINCKTVKYFLRANNIDKAVEVASLFTKNDDSVNGIKDLHLVEASWFIVEQAEAYYRLYLDRKKKLDDLASLKKEVESDKSEQIANDIKENQWLVRKYKGLALKRFNAIPKFYKQFEDDQLDFHSYCMRKGTPRAYLEMLEWGKALYTKPMYVRAMKEASKLYFQMHDDRLKRKS-----DSLDENSDEIQNNGQNSSSQKKKAKKEAAAMNKRKETEAKSVAAYPSDQDN---------DVFGEKLIETSTPMEDFATEFYNNYSMQVREDERDYILDFEFNYRIGKLALCFASLNKFAKRFGTTSGLFGSMAIVLLHATRNDTP------FDPILKKVVTKSLEKEYSENFPLNEISNNSFDWLNFYQEKFGKNDINGLLFLYRYRDDVPIGSSNLKEMIISSLSPLEPHSQ------------------NEILQYYL------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: **. * . *: ** ***::.**: . **. * .* ::**:*** * :*.:::* . * :.. * :* ** *: *. *:*.*:** : **: . * ** :**: ** *: *::. :* : . :*.* . *:: .: : : * . :. * : . : .*.:** *:*:*::: :: ::.:.** : : **:.: * . : ::* : .* ::. * .*** * **: : . :* :*: *: :**.: . ::: .:: : :* *. * .::.*:: . .::*::.: * .* : . .::*. :*:**: : . * ***:.*:: ****:*: : *.:* ** * * ::*.: :* **:**.* .**.*:*. :.:* *:.: **: :....:.:*: ::. ** .* * ** : * :**: : : :.: :: :**:***:***** * *:*: :*. ..* :*:*.:* : * ::*: ::*. *. .. * : .*::: .:. :***: * : .. : . ::: ::. *** . . *::. * :* . . .:: . ::: **: * * * : .:.: . :. .: .. . . . :*:: .. : .: : : .: . : :: . ..:. . : . . . : * ", "identical_positions": 171, "similar_positions": 284, "identity": "17.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2399", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70551-1", "uniprot_id": "SRPK1_MOUSE", "id": "O70551-1", "name": "SRSF protein kinase 1", "aln": "-----------------------------------------MERKVLALQARKKRTKAKK------DKAQRKPETQHRGSAPHSESDIPEQE---EEILG----------------------------------------------------------------------------SDDDEQEDPNDYCKGGYHLVKIGDLFN-GRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPN---GEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQRSGAPPPSGSAVSTAP----QPKPADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQKRPNKQEESESPVDRPLTENPPNKMTQEKLEESNSIGQDQTLTERGGEGGAPEIN--CNGVIGVVNYPENSNNE-TLRHKEDLHNAN-DCDVHTLKQEPSFLNSSNGDSSPSQDTDSCTPTAS---ETMVCQSSAEQS--LTRQDITQLEESIRADTPSGDEQE----PNGALDSKGKFSAGNFLINPLEPKNAEKLQ-----------VKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEDYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHITKLKPWGLLEVLVEKYEWPQEEAAGFTDFLLPMLELMPEKRATAAECLRHPWLNS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KLN3-1", "uniprot_id": "Q4KLN3_RAT", "id": "Q4KLN3-1", "name": "SRSF protein kinase 1", "aln": "-----------------------------------------MERKVLALQARKKRTKAKK------DKAQRKPETQHRGSAPHSESDIPEQE---EEILG----------------------------------------------------------------------------SDDDEQEDPNDYCKGGYHLVKIGDLFN-GRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPN---GEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQRSGAPPPSGSAVSTAP----QPKPADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQKRPNKQEESESPVERPLTENPPNKMTQEKLEESSSIGQDQTLTEHGGEGGAPEIN--CNGVIGIVNYTANSNNE-TLRLKEDLHNAN-DCDGRTLKQEPSFLSSPNGDSSPSPETDSCTPSGSEVPETMACQASVERSLTLTQQDITHLQERIRAHTPSGDEQERE--HNGALDSKGKFSAGNFLINPLEPKNAEKLK-----------VKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEDYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHITKLKPWGLLEVLVEKYEWPQEEAAGFTDFLLPMLELMPEKRATAAECLRHPWLNS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96SB4-2", "uniprot_id": "SRPK1_HUMAN", "id": "Q96SB4-2", "name": "SRSF protein kinase 1", "aln": "-----------------------------------------MERKVLALQARKKRTKAKK------DKAQRKSETQHRGSAPHSESDLPEQE---EEILG----------------------------------------------------------------------------SDDDEQEDPNDYCKGGYHLVKIGDLFN-GRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPN---REMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQRSGAPPPSGSAVSTAP----QPKPADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQKRPNKQEESESPVERPLKENPPNKMTQEKLEESSTIGQDQTLMERDTEGGAAEIN--CNGVIEVINYTQNSNNE-TLRHKEDLHNAN-DCDVQNLNQESSFLSSQNGDSSTSQETDSCTPITSEVSDTMVCQSSSTVGQSFSEQHISQLQESIRAEIPCEDEQEQE--HNGPLDNKGKSTAGNFLVNPLEPKNAEKLK-----------VKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPHSGEEYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHITKLKPWGLFEVLVEKYEWSQEEAAGFTDFLLPMLELIPEKRATAAECLRHPWLNS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YZP6-1", "uniprot_id": "A0A8M6YZP6_DANRE", "id": "A0A8M6YZP6-1", "name": "non-specific serine/threonine protein kinase", "aln": "-----------------------------------------MERKVLALQARKKRAKAKKST----KKPAHPPRGASQQQPPPTETQIQEPD---EEILG----------------------------------------------------------------------------SDDEEQEDPNDYCKGGYHHVKIGDLLN-SKYHVIRKLGWGHFSTVWLAWDIQGKRFVAMKVVKSAEHYTETALDEIKLLRSVRNTDPDDPN---REMVVQLLDDFKISGVNGTHVCMVFEVLGHHLLKWIIKSNYQGLPLPCVKSIIRQVLQGLDYLHTKCQIIHTDIKPENILMSVEELYVRRLAAEATEWQKAGAPPPSGSAVSTAP----APKQAPKMSKNKKKKLKKKQKRQAELLEKCIMDLEEMEIGPEGREEEEDDPESPKSPSCAPLR--------QASLQEIATEDIIMDTRERLTSDASVELN--CNGCLHSSKTQPEEDEQGDLQYGQLLQEDHHNANAGPEDTAQSMYEYCNGAESPELDQACYSNGTS-------GQEQLEDG-ELATEEQHQQKTRTRAREQNKDKIK-----------DDKLSAGSLLVNPLDPLNADKIK-----------VKIADLGNACWVHKHFTEDIQTRQYRSLEVLLGSGYNTPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHLALIIELLGHIPRHYALSGKFSQEYFCRKGDLKHITKLKPWGLLDVLMDKYEWPQEEAQTFSDFLLPMLELLPEKRATASDCLRHPWLAL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A6M3Q7C8-1", "uniprot_id": "A0A6M3Q7C8_DROME", "id": "A0A6M3Q7C8-1", "name": "non-specific serine/threonine protein kinase", "aln": "------------------------------------MNKADVNRRVLAIQAKKKRHKNRKRGKQNGTNPQEQSNSSQNQNPKPSSNPIPEPNRSSENLQAPDNANNSHLNAPSSAAFSKATATATASTSSGGSAGTPDQYQPPKKTQAKAKPNTQKEHQQQPPRSSSNESYESETFSDNEDQELMEDYCKGGYHPVNIGDLFH-DRYHVIRKLGWGHFSTVWLCWDLQAMGYVAIKIVKSAPHFAETARDEIKILKTVRETDPSNPR---RHKTVQMLDDFKITGVNGTHICMVFEVLGDNLLKLIRKSNYRGIPLANVKTITRQVLEGLDYLHTCCKIIHTDIKPENVLLCVDEPHVRSLATEATQLYCMNSKMYP-SLVSRAPKEYREPPITGKMSKNRKKKLKKKAKKRMELFKQQRDYLEQADGQGAINPNEVQNGDAGISDADEYFDANSVEDNVHVAAGQPSRKQREERKAPPEQSEEAQEQDPLTEGTDKAKKKKKKKNKNKSNQSKGQQPPQLENSTSSAESSSALKSQQANGSNSTTNNKSNTNSSGTLKGQSNGKKMPLRPKQEKQGSNHQLNNNNSKPNSNSDSKISSGSVENTSSATNGPHSNSTLPTPPPPPQAKHKAKKDPALDECNVHVKIADLGNACWVDRHFTEDIQTRQYRSLEVIIGAGYNTSADIWSTACMVFELATGDYLFEPHSGESYTRDEDHLAHIIELLGPIPREILLNGTYAAKSFTRSCELRNISGLKPWGLMDVLLEKYEWSQKDAASFASFLTPMLEFDPNKRATAAECLQHPWLRXDTMQPGCWLRATQPATADGDGGALAGTGTGKGTRARATALKGGSPAVPADGEVGRGYIESSASVATLASISSIASTSAAAMAALKARPYLVAPFVTTASAPPTPHPHASISTSTARTAPATPTRRRIAPEDDLNLVEDLDVALAQIEDTQTHTKNKSQRFFWRKALRRVFQRRKXRRRRQDLPRWHRPARRCRRRNLAERVRRICACCAYGQILLRAARVALLSCIRWRTRGNIRNNNFYFSNH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03656-1", "uniprot_id": "SKY1_YEAST", "id": "Q03656-1", "name": "Serine/threonine-protein kinase SKY1", "aln": "MGSSINYPGFVTKSAHLADTSTDASISCEEATSSQEAKKNFFQRDYNMMKKAPAPTKSKLSLALQTSKSSSSANGTVQEDTSSKTEDFSTKSIKKKPDSG-------------------------------------------------VESHVSIQSDSGPQSDSDLDSDSSISSCDERNEESLKDYRPGGYHPAFKGEPYKDARYILVRKLGWGHFSTVWLAKDMVNNTHVAMKIVRGDKVYTEAAEDEIKLLQRVNDADNTKEDSMGANHILKLLDHFNHKGPNGVHVVMVFEVLGENLLALIKKYEHRGIPLIYVKQISKQLLLGLDYMHRRCGIIHTDIKPENVLMEIGDVEGIVQMVEALDKQKREAKRLQRHVSRSSD-------ITANDSSDEKWAECQTSMPCGSSSNSKSRSIEKDLSKRCFRRPRRHTIITGSQPLPSPISSS----NFFEMRAHFCGSSHNSFSSVSGNRNIPSSIN---NNSINNGIGIKNSNNSFLNSVPHSVTRMFINEDSNDNNNNDNSKNKNNNNNNSNNNNNED-----------IMNTPLHEEQLADSLSTFDISNISQSSDTNGPYIS-----------NTMDSNSNVSTDINSPENLIQIK-------------IADLGNACWYDEHYTNSIQTREYRSPEVLLGAPWGCGADIWSTACLIFELITGDFLFEPDEGHSYTKDDDHIAQIIELLGELPSYLLRNGKYTRTFFNSRGLLRNISKLKFWPLEDVLTEKYKFSKDEAKEISDFLSPMLQLDPRKRADAGGLVNHPWLKDTLGMEEIRVPDRELYGSGSDIPGWFEEVRDHKRH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:* :: * : :. .. . .. . : . : . .*: ::* :** **** . *: : :* ::*************. *: .**:*:*:. ::*:* ***::*: *.::* . . :::**.*: .* **.*: *******.:** * * :::*:** ** * :*:* ****:* * **********:*: : : .** : : : : : *.:.* :. . :. :*: . . . : . . . : :. :.::. : . . *. ... : : . :. . . : ... * : : ********* ..*:*:.****:*** **::*: :. ********: *** ***:****..*..*::*:**:* ****** :* *.:: * *::*: ** * * :** :**::.:.:* ::.** ***:: *.*** *. :.**** ", "identical_positions": 167, "similar_positions": 163, "identity": "15.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2403", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GFX3-1", "uniprot_id": "A0A8I6GFX3_RAT", "id": "A0A8I6GFX3-1", "name": "RNA uridylyltransferase", "aln": "MEEPKTSKNENHEPKKNIICEESKAVKIITNQTLKPRNDKSMTEIGTSSLNRNSSKKTKQNDICIEKTEAKSCKVNAASVPGPKDLGLVLRDQSHCKVKKLPNSPMKAQKG-SSQTKLEKAPSLQAKAEKVPKSPNLPVKVEKTPCTTAAATTEKALNSQRKEENVPTSQMKLQKTPRSPLEPENVPSLLLKENVKQTESQQTGKKLTSSFVSMDKRNSAALQGEKSTLENSSLSQKQQTQADNIADSDDSASGMEDTSDDLSKMKNEESNKENSSEMDYLENATVIDESTLTPEQKLGLKQAEERLERDHIFRLEKRSPEYTNCRYLCKLCLIHIENIQGAHKHIKEKRHKKNILEKQEESELRSLPSPSPAHLAALSVAVVELAKEQGITDDDLRIRQDIVEEMSKVIVTFLPECSLRLYGSSLTKFALKSSDVNIDIKFPPKMNHPDLLIQVLGILKKSALYVDVESDFHAKVPVVVCKDRKSGLLCRVSAGNDMACLTTDLLAALGKVEPVFTPLVLAFRYWAKLCYIDSQTDGGIPSYCFALMVMFFLQQRKPPLLPCLLGSWIDGFDPKRMDDFQLKGIVEEKFVKWEYNSSSATEKSLIADENTAKADQPKDDTRKTETDNQSNAVKAKHGKSPLTLEAPNQVPLGQLWLELLKFYTLDFALEEYVICVRIQDILTRENKNWPKRRIAIEDPFSVKRNVARSLNSQLVYEYVVERFRAAYRYFACPQRKGGNKSTVDLKKKEKGKLSNKKPVKSDCSATNGCVLG-ESTEKVNMERGQPLKHDEMEFTSQRCIVDNDRLLVNELGLADHGQDSSSLSTGSEGSELQQKSAEKQGDLTPSETSLKKELSQCHCTG---TPDGAGSAGTDCRSNLEMESSHQIVCNNISATSCNCKATEVASDLIDDDNLPSQELYYVFDKFILTSGKPPTIVCSICKKDGHSKNDCPEDFRKIDLKPLPPMTNRFREILDLVCKRCFDELSPPCSEQHNREQILIGLEKFIQKEYDEKARLCLFGSSKNGFGFRDSDLDICMTLEGHENAEKLNCKEIIENLAKILKRHPGLRNILPITTAKVPIVKFEHRRSGLEGDISLYNTLAQHNTRMLATYAAIDPRVQYLGYTMKVFAKRCDIGDASRGSLSSYAYILMVLYFLQQRKPPVIPVLQEIFDGKQIPQRMVDGWNAFFFDKTEELKKRLPSLGKNTESLGELWLGLLRFYTEEFDFKEYVISIRQKKLLTTFEKQWTSKCIAIEDPFDLNHNLGAGVSRKMTNFIMKAFINGRKLFGTPFYPLIGREAEYFFDSRVLTDGELAPNDRCCRVCGKIGHYMKDCPKRKSSLLFRLKKKDSEEEKEGNEEEKDSRDLLDSR------------DLRCFICGDAGHVRRECPEVKMARQRNSSVAAAQLVRNLVNAQQVAG-SAQQQSDQSIRTRQSSECSDS---PSYSPQPQPFPQNSPQPSALPPPPSQPGSQPKLGPPQQGGQPPHQVQMPLYNFPPSPPAHYSP-MHGMGLLPMHPLQIPAPSWPIHGPMLHSAP----------GSTPSN----IGLNDPSIIFAQPAARPMAIPSSSHDGH-WP-RTVAPNSLVNNGAVGNSEP----RFRGLNP-PIPWEHAPRPHFPLVPASWPYGLHQNFMHQGNPRFQP-KPFYAQAERCATRRSRERCPHPPRGNVSE-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RX14-1", "uniprot_id": "TUT4_MOUSE", "id": "B2RX14-1", "name": "Terminal uridylyltransferase 4", "aln": "MEEPKTSKNENHEPKKNIICEESKAVKIISNQTLKPRNDK--SEIGTSSLNRNSSKKTKQNDICIEKTEAKSCKVNAASVPGPKDLGLVHRDQSHCKMKKLPNSPMKAQKG-SSQTKLEKTPSLQTKAEKVPKSPNLPVKAEKAPCTTAEATTEKALNSQRKEENTPTSQMKLQKTPRSPLEPENVPSLLLKENVKQTESQQTGKKLTSSFVSMDKRKSEALQGEKSALENSSLSQKQQTQTDNIADSDDSASGIEDTADDLSKMKSEESNKENSSEMDYLENATVIDESALTPEQRLGLKQAEERLERDHIFRLEKRSPEYTNCRYLCKLCLIHIENIQGAHKHIKEKRHKKNILEKQEESELRSLPSPSSAHLAALSVAVVELAKEQGITDDDLRIRQDIVEEMSKVIMTFLPECSLRLYGSSLTKFALKSSDVNIDIKFPPKMNHPDLLIQVLGILKKSALYIDVESDFHAKVPVVVCKDRKSALLCRVSAGNDMACLTTDLLAALGKVEPVFTPLVLAFRYWAKLCYIDSQTDGGIPSYCFALMVMFFLQQRKPPLLPCLLGSWIEGFDPKRMDDFQLKGIVEEKFVKWEYNSSSATEKNLIADENKAKADEPKDDTKKTETDNQSNAAKAKHGKSPLTLEAPNQVPLGQLWLELLKFYTLDFALEEYVICVRIQDILTRENKNWPKRRIAIEDPFSVKRNVARSLNSQLVYEYVVERFRAAYRYFACPQKKGGNKSTMDPKKKEKGKLSSKKPVKSDCSATNCCILG-ESAEKIHMERGQPAKHDETEFTSQRCIVDNDSLLVNELGLANHGQDSSSLSTASGGSDLKQKSAEKQGDLTPSETSLKKELSQCICIG---TPDGAESAGTDCRSNLEMDSSHQIVCNNVSATSCNCKATEVTSDLVDEDNLPSQELYYVFDKFILTSGKPPTIVCSICKKDGHSKNDCPEDFRKIDLKPLPPMTNRFREILDLVCKRCFDELSPPCSEQHNREQILIGLEKFIQKEYDEKARLCLFGSSKNGFGFRDSDLDICMTLEGHENAEKLNCKEIIENLAKILKRHPGLRNILPITTAKVPIVKFEHRRSGLEGDISLYNTLAQHNTRMLATYAAIDPRVQYLGYTMKVFAKRCDIGDASRGSLSSYAYILMVLYFLQQRKPPVIPVLQEIFDGKQIPQRMVDGWNAFFFDKTEELKKRLPSLGKNTESLGELWLGLLRFYTEEFDFKEYVISIRQKKLLTTFEKQWTSKCIAIEDPFDLNHNLGAGVSRKMTNFIMKAFINGRKLFGTPFYPLIGREAEYFFDSRVLTDGELAPNDRCCRVCGKIGHYMKDCPKRK-----RLKKKDSEEEKEGNEEEKDSRDLLDSR------------DLRCFICGDAGHVRRECPEVKMARQRNSSVAAAQLVRNLVNAQQVAG-SAQQQSDQSIRTRQSSECSDS---PSYSPQPQPFPQNSPQPSALPPPPSQPGSQPKLGPPQQGGQPPHQVQMPLYNFPQSPPAHYSP-MHSMGLLPMHPLQIPAPSWPIHGPMLHSAP----------GSTPSN----IGLNDPSIIFAQPAARPMAIPSPSHDGH-WP-RTVAPNSLVNNGAVGNSEP----RFRGLNP-PIPWEHAPR-HFPLVPASWPYGLHQNFMHQGNPRFQP-KPFYAQADRCATRRCRERCPHPPRGNVSE-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TAX3-1", "uniprot_id": "TUT4_HUMAN", "id": "Q5TAX3-1", "name": "Terminal uridylyltransferase 4", "aln": "MEESKTLKSENHEPKKNVICEESKAVQVIGNQTLKARNDKSVKEIENSSPNRNSSKKNKQNDICIEKTEVKSCKVNAANLPGPKDLGLVLRDQSHCKAKKFPNSPVKAEKATISQAKSEKATSLQAKAEKSPKSPNS-VKAEKASS----------------------YQMKSEKVPSSPAEAEKGPSLLLKDMRQKTELQQIGKKIPSSFTSVDKVNIEAVGGEKCALQNSPRSQKQQTCTDNTGDSDDSASGIEDVSDDLSKMKNDESNKENSSEMDYLENATVIDESALTPEQRLGLKQAEERLERDHIFRLEKRSPEYTNCRYLCKLCLIHIENIQGAHKHIKEKRHKKNILEKQEESELRSLPPPSPAHLAALSVAVIELAKEHGITDDDLRVRQEIVEEMSKVITTFLPECSLRLYGSSLTRFALKSSDVNIDIKFPPKMNHPDLLIKVLGILKKNVLYVDVESDFHAKVPVVVCRDRKSGLLCRVSAGNDMACLTTDLLTALGKIEPVFIPLVLAFRYWAKLCYIDSQTDGGIPSYCFALMVMFFLQQRKPPLLPCLLGSWIEGFDPKRMDDFQLKGIVEEKFVKWECNSSSATEKNSIAEENKAKADQPKDDTKKTETDNQSNAMKEKHGKSPLALETPNRVSLGQLWLELLKFYTLDFALEEYVICVRIQDILTRENKNWPKRRIAIEDPFSVKRNVARSLNSQLVYEYVVERFRAAYRYFACPQTKGGNKSTVDFKKREKGKISNKKPVKSNNMATNGCILLGETTEKINAEREQPVQCDEMDCTSQRCIIDNNNLLVNELDFADHGQDSSSLST-SKSSEIEPKLDKKQDDLAPSETCLKKELSQCNCIDLSKSPDPDKSTGTDCRSNLETESSHQSVCTDTSATSCNCKATEDASDLNDDDNLPTQELYYVFDKFILTSGKPPTIVCSICKKDGHSKNDCPEDFRKIDLKPLPPMTNRFREILDLVCKRCFDELSPPCSEQHNREQILIGLEKFIQKEYDEKARLCLFGSSKNGFGFRDSDLDICMTLEGHENAEKLNCKEIIENLAKILKRHPGLRNILPITTAKVPIVKFEHRRSGLEGDISLYNTLAQHNTRMLATYAAIDPRVQYLGYTMKVFAKRCDIGDASRGSLSSYAYILMVLYFLQQRKPPVIPVLQEIFDGKQIPQRMVDGWNAFFFDKTEELKKRLPSLGKNTESLGELWLGLLRFYTEEFDFKEYVISIRQKKLLTTFEKQWTSKCIAIEDPFDLNHNLGAGVSRKMTNFIMKAFINGRKLFGTPFYPLIGREAEYFFDSRVLTDGELAPNDRCCRVCGKIGHYMKDCPKRKS-LLFRLKKKDSEEEKEGNEEEKDSRDVLDPRDLHDTRDFRDPRDLRCFICGDAGHVRRECPEVKLARQRNSSVAAAQLVRNLVNAQQVAG-SAQQQGDQSIRTRQSSECSES---PSYSPQPQPFPQNSSQSAAITQPSSQPGSQPKLGPPQQGAQPPHQVQMPLYNFPQSPPAQYSP-MHNMGLLPMHPLQIPAPSWPIHGPVIHSAP----------GSAPSN----IGLNDPSIIFAQPAARPVAIPNTSHDGH-WP-RTVAPNSLVNSGAVGNSEP----GFRGLTP-PIPWEHAPRPHFPLVPASWPYGLHQNFMHQGNARFQPNKPFYTQ-DRCATRRCRERCPHPPRGNVSE-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PS24-1", "uniprot_id": "A0A8M1PS24_DANRE", "id": "A0A8M1PS24-1", "name": "RNA uridylyltransferase", "aln": "MEDPKS-------PVKALKPSRSNAGKVSSSKPQR-------ESVKTPSRSKDGVPRVK------------------EEAPGGRTRTDSPQEQARGKTRRLTGRTNSGERG---------------------------------------------------------------------------------------------------------------KGKPSANEARQQTQENKTAVRNSGPVKDGGATAEEISAHNNNTTTTTKDKMPGVEAGRQRVEEVVEVLNLTSDQQLGLKQAEERLQRDYIHRLLKPSPEYPNFQYLCKLCSVHVENIQGAHKHIKEKRHKKNIMEKREENELRALPAPSPAQLRALDSAVLEAAELHGISEEDFTLRQAVVLRMEGIIQKQLAACSLRLYGSCLTRFAFKTSDVNIDVSYPSTMTQPDVLIQVLEILKNCVEFAEVESDFHAKVPVVFCRDEASGLMCKVSAGNDVACLTTNHLAALSRLEPRLVPLVLAFRYWANLCHIDCQAEGGIPSYSLSLMVIFFLQQRYKPILPVYLGHWIKGFEVKRVDEFHLTGVQSEVFVGWEHRPAPAGE---------GRGDGRSKPEPKTPVEKKEKKLEQTTGKSRLKLEEPVSASLGQLWLELLRFYTLEFALEEHIISIRLKELLPRELKNWPRRRLAIEDPFALKRNVARSLNSQMVFEYIQERFRTAYKYFACPQ----------------------------------------SRNRVNTSR---------------------RLLRNKHRLNEAAR-SDSLERKKRDEEDGDSSDEDEERDLEEEESLRGTFTDLLVGD-------GGIDGEGVSQEISRNMSPSVLNGLLMDTDEDDEEEEKDHEMEEQDNIAPEDLHYIFDRMIFTGGKPPTVVCSICKRDGHLKDKCPEDFKKIELKPLPPMTELFREILDCLCVLCYRELSPTLIEQQKREQILGSLERFIRKEYNDKAQLCLFGSSKNGFGFRDSDLDICMTLEGHDTAEKLNCKEIIEGLAKVLKKHTGLRNILPITTAKVPIVKFEHRQSGLEGDISLYNTLAQHNTRMLATYAAIDPRVQYLGYTMKVFAKRCDIGDASRGSLSSYAYILMVLYFLQQRQPPVIPVLQEIFDGNTTPQRMVDGWNAFFFDDLDELRRRLPELHQNRETVGELWLGLLRFYTEEFDFKEHVISIRQRKRLTTFEKQWTSKCIAIEDPFDLNHNLGAGVSRKMTNFIMKAFINGRKLFGTPFYPQPGTEADYFFDSKVLTDGELAPNDRCCRICGKIGHYMKDCPKRR-----RMKKKENEREEEVREEDREPR------------------ERRCFQCGDMGHVRRDCPDYKHLRQRAAPGPVPHMVRAMASSQSIPIPQAASVQERVGRNRQPSECSDTRQTPPYSPQASPYSQTSVSPQNTKPSSSSSSSSSTK--PSQPPQVP-QVQLPLFSFPHSHPGQYHAGLSALGLLPAQPPLASG-SWPIHGPLVQPTASQHSKFTVQGGGGGSGGGQAVNLNDPSIIFAQPAAAAGRVAVGRERGHPWHNHHLGPGPLVGNGTVNKPDPNFPTQFGGVNPGSRSWDHGGAAQYSISPSFMPYRLPP-YLQQPN------KPFISQGSVVANQHYP-LIQHGRQGNLNYIQQKK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:.*: * * : ..*:* :: .:. : .: ..* .::. : * . ** : ::*:: * :::.. . ..::. *: .: : :*:::* . * . .*..: *: : . .: .. .:* . * . . *:: **.:*:**********:**:*.** * ****.* :****** :*:*******************:**:**.***:**.**.*:* **. **:* *: :**:::*: :** :* .*. :* . *. ********.**:**:*:******:.:*..*.:**:**:** ***: . : :************.*:*. *.*:*:******:*****: *:**.::** : **********:**:**.*::******.::***:****** *:** ** **.**: **:*:*:*.*: .* ** ** ..:.* * .:.* .. ** .:::.: : . *** * ** * ..*********:****:*****::*.:*::::*.** ****:**:******::***********:*:**: ****:**:****** : :::: .* ** *: : : .: *.**. . ..: . :.: .* .*: ::: . * . .::. : * . : *. : : * :: ::**:..::*:*:**::*:*.*****:******:*** *:.*****:**:********: ****** :* *: ****. **::***** .**:**:***::**:***************************:.***********.***:**:*.*********************:***********************************************************************:*************: **************. :**::***.* :* *::*******************:******:* ****************************************************** * **:*****:***************:**************: *:***:.*.*:* .**:::.* : *** *** *****:**: * *** :. ...::** :..:*.:. .* . :: *.**.****:: *.****..*:.*.* .. ..*...*... *.* * * ***:**:.** * *.:* . : :**** :* .. *******:::.:. *. *. :.************* . :. . ** * : :.*..**..*:*.:.:* * *:.* . .*:*. ::.: *: ** * :::* * *** :* . *.:: * :**:. ", "identical_positions": 770, "similar_positions": 392, "identity": "45.27%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2411", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61191-1", "uniprot_id": "HCFC1_MOUSE", "id": "Q61191-1", "name": "Host cell factor 1", "aln": "-----------------------------------------MASAVSPANLPAVLLQPRWKRVVGWSGPVPRPRHGHRAVAIKELIVVFGGGNEGIVDELHVYNTATNQWFIPAVRGDIPPGCAAYGFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWEWKRLKAKTPKNGPPPCPRLGHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYILELR-PGSGVVAWDIPITYGVLPPPRESHTAVVYTEKDNKKSKLVIYGGMSGCRLGDLWTLDIETLTWNKPSLSGVAPLPRSLHSATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKCTNTLACLNLDTMAWETILMDTLEDNIPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLWYLETEKPPPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLVPQAATAPPSTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPASVRMVVPTQSAQGTVIGSNPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTVAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAANTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALIS---NLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGAHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQETAASLVTSAVGQQNGNVVRVCSNPPCETHETGTTNTATTATSNMA-GQHGCSNPPCETHETGTTSTATTAMSSMGTGQQRDTRR--TTNTPTVVRITVAPGALERVQGTVKPQCQTQQTNMTTTTMTVQATGAPCSAGPLLRPSVALESGSHSPAFVQLALPSVRVGLSGPSSKDMPTGRQPETYHTYTTNTPTTTRSIMVAGELGAARVVPTSTYESLQASSPSSTMTMTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSN-------AGSAQRVCSNPPCETHETGTTHTATTATSNGGAGQPEGGQQPASGHPCETHQT--TSTGTTMSVSVGTLIPDATSSHGTLESGLEVVAVPTVTSQAGSTLLASFP--TQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVASTQGDSTNITSASAITTSVSSTLPRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTPLMGESTEVLSASQTPELQ--AAVDLSSTGDPSSGQEPTTSAVVATVVVQPPPP------------------TQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAAVTQAELGHLSAEGQEGQATTIPIVLT-QQELAALVQQQQQLQEAQAQAQQQHH-------LPTEALAPADSLNDPSIESNCLNELASAVPSTVALLPSTATESLAPSNTFVAPQP-VVASPAKMQAAATLTEVANGIESLGVKPDLPPPPSKAPVKKENQWFDVGVIKGTSVMVTHYFLP--PDDAVQSDDDSGTVPDYNQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISKSP-DGAHLTWEPP-SVTSGKIIEYSVYLAIQSSQASGEPKSSTPAQLAFMRVYCGPSPSCLVQSSSLSNAHIDYTTKPAIIFRIAARNEKGYGPATQVRWLQETSKDSSGTKPASKRPMSSPEMKSAPKKSKADGQ-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZN95-1", "uniprot_id": "HCFC1_RAT", "id": "D3ZN95-1", "name": "Host cell factor 1", "aln": "-----------------------------------------MASAVSPANLPAVLLQPRWKRVVGWSGPVPRPRHGHRAVAIKELIVVFGGGNEGIVDELHVYNTATNQWFIPAVRGDIPPGCAAYGFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWEWKRLKAKTPKNGPPPCPRLGHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYILELR-PGSGVVAWDIPITYGVLPPPRESHTAVVYTEKDNKKSKLVIYGGMSGCRLGDLWTLDIETLTWNKPSLSGVAPLPRSLHSATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKCTNTLACLNLDTMAWETILMDTLEDNIPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLWYLETEKPPPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLVPQAAAAPPSTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPASVRMVVPTQSAQGTVIGSNPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTVAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAANTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALIS---NLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGAHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSAVGQQNGNVVRVCSNPPCETHETGTTNTATTATSNMA-GQHGCSNPPCETHETGTTSTATTAMSSMGTGQQRDARR--ATNTPTVVRITVAPGALERAQGTVKPPCQTQQTNMTSTTMTVQATGAPCSAGPLLRPSVALETGSHSPAFVQLALPSVRVGLSGPSSKDVPTGRQPETYHTYTTNTPTTARSIMVAGELGTARVVPTSQYDCLQASSPSSTMTMTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSN-------AGSAQRVCSNPPCETHETGTTHTATTATSNGGAGQPEGGQQPASGHPCETHQT--TSTGTTMSVSVGALIPDATPSHGTLESGLEVVAVPTVTSQAGATLLASFS--TQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVASTQGDSTNITSASAITTTVSSTLPRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTPLMGESAEVLSASQTPELQ--AAVDLSSTGDPSSVQEPTTSAVVATVVVQPPQP------------------TQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAAVTQAELGHLSAEGQEGQATTIPIVLT-QQELAALVQQQQQLQEAQAQAQQQHH-------LPTEALAPADSLNDPSIESNCLNELASAVPSTVALLPSTATESLAPSNTFVAPQPVVVASPAKMQAAATLTEVANGIESLGVKPDLPPPPSKAPIKKENQWFDVGVIKGTSVMVTHYFLP--PDDAVQSDDDSGTVPDYNQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISKSP-DGAHLTWEPP-SVTSGKIIEYSVYLAIQSSQASGEPKSSTPAQLAFMRVYCGPSPSCLVQSSSLSNAHIDYTTKPAIIFRIAARNEKGYGPATQVRWLQETSKDSSGTKPASKRPMSSPEM-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51610-1", "uniprot_id": "HCFC1_HUMAN", "id": "P51610-1", "name": "Host cell factor 1", "aln": "-----------------------------------------MASAVSPANLPAVLLQPRWKRVVGWSGPVPRPRHGHRAVAIKELIVVFGGGNEGIVDELHVYNTATNQWFIPAVRGDIPPGCAAYGFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWEWKRLKAKTPKNGPPPCPRLGHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYILELR-PGSGVVAWDIPITYGVLPPPRESHTAVVYTEKDNKKSKLVIYGGMSGCRLGDLWTLDIDTLTWNKPSLSGVAPLPRSLHSATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKCTNTLACLNLDTMAWETILMDTLEDNIPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLWYLETEKPPPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALIS---NLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMA-GQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQG-SKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGR-----HSHAVSTAAMTRSSVGAGEPRMAPVC-----ESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSN-------AGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQT--TSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFP--TQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELP--AAVDLSSTGEPSSGQESAGSAVVATVVVQPPPP------------------TQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLT-QQELAALVQQQQ-LQEAQAQ-QQHHH-------LPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLPPPPSKAPMKKENQWFDVGVIKGTNVMVTHYFLP--PDDAVPSDDDLGTVPDYNQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISKSP-DGAHLTWEPP-SVTSGKIIEYSVYLAIQSSQAGGELKSSTPAQLAFMRVYCGPSPSCLVQSSSLSNAHIDYTTKPAIIFRIAARNEKGYGPATQVRWLQETSKDSSGTKPANKRPMSSPEMKSAPKKSKADGQ-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PQY4-1", "uniprot_id": "A0A8M9PQY4_DANRE", "id": "A0A8M9PQY4-1", "name": "Host cell factor 1", "aln": "-----------------------------------------MASSG------TSVLQPRWKRVLGWSGPVPRPRHGHRAVAIKELMVVFGGGNEGIVDELHVYNTATNQWFIPAVRGDIPPGCAAYGFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWEWKRLKPKAPKNGPPPCPRLGHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYTLELR-PGSNVAGWDIPITYGVLPPPRESHTAVVYTEKTSKKSRLIIYGGMSGCRLGDLWTLDIDTLTWNKPAISGAAPLPRSLHSATTITNKMFVFGGWVPLVMDDVKVATHEKEWKCTNTLACLNLDSMSWETILMDTLEDNIPRARAGHCSVAINNRLYVWSGRDGYRKAWNNQVCCKDLWYLETDRPQPPSRVQLVRANTNSLEVSWGAVPTADTYLLQLQKYDIPA-ATAATSPTVNPMPSVPVNSPKSPVPAAAAPAAQSMPLSGVTLVPQVPSPTTAMPTSPLAASPRG--------------PAILKVAAPHSTPGTSVVTVRQATPGAKSPVTVTSLPAGVRMVVPAQSTQGTPIGSSPQMSGMAALAAAAAATQKIPPSSATTVLNVPAGATLVKTVAVTPGSTTLPATVKVAS-PVMVTNPATRMLKTAAAQVGTSAISTPNTPTRPIITVHKSGTVTVAQQAQVVTTMVGGVTKTITLVKSPITMGGSGALYSQLSSLGKVMSVVQTKPVQTSAVTGQAGSSPVT-LIQTKTPLPAGTILKLVTSADGKPTTIITTSQAGGTGTKPTILGISSVSPTTTNKPGTTIIKTIPMSALQ---GATGVTSSAGIKSPITIITTKVVTPGTGTPGKIITAVPKLT-GAGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVSPGTVSADKPTVTTLVVKGTTGVTTLGTVTGTVSTSVAGAN--VANASLATPVTTLASIATLSSQVINPTAITVSAAQTNLATA--------TIQSASQPTQVTLITTPSGAEAQPGQDLPVSFLASPTSEQPSTTGADAGDSAGDGAT-TVTLVCSNPPCETHETGTTNTATT-ASAKIG--------------------------------TEQICSNPPCETHVTGTTNTSTTASANMGRAQQVCTNPPSETHDTGTTNTATTASCNMGSTEMGTVNSKPGSSSPPASSSSEPSTPVSESGAEAGVMRPENLRTGTTYTSTTARSNMGSDQTGTVQSSNKSQAAISSTMMPVSSSESPGDTDTSDVSGSVCSNPPCETRETGTTSTPTQSSADMESGQSGSVQRVCSNPPCETHETGTTNTSTQASSSMAAGQSGTAQRVCSNPPCETHETGTTNTPTQASSSLGAGQSGTVQRVCSNPPCETHETGTTNTPTQASSSLGAGQSGTVQRVCSNPPCETHETGTTNTQTQASSTLGAGQSGAVQRVCSNPRETHETGTTNTPTQASSGIGAGQNGTVQMVCSNPPCETHETGTTNTATTATSNLETGEG---AAQQAGDGQSESATSTEPTSSTEPAN--PATQSRAITTVTQATPTPGPSVPEISSMAGSAVVSETPGEAEAMEQASAEAVAAGEEPMQTESQGELSEEGAVRVVAIDESAAGDGSTVLQVHVAMEAQPGQGDQAEQMEAGVEAAEAMSLAAQDSEALALPQELMSAEGQ-QTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVLS-GE----------------GDAGHDGQ--QATTIPIVLT-QQELAALVQQQQQLQEAQAAAAQQLSAEAAAAALPTEGLAPADSLNDPASESNGHEMPTAVTGAVVRLLPRTSAETLAPSSTFAPSQPLVVASPAKMQAATALAEVANGIESAAGKQEAPPVVVKPPVKKENQWFDVGIVKVTNMVVTHYYVP--ADDSAVTDDDSGAIPDYSRMKKIELSPGTAYKFRVAGINACGRGTFSEVSAFKTCLPGFPGAPCAIKISKSP-DGAHLTWEPP-SVTSGKIIEYSVYLAIQSSQT-VEAKASAPAQLAFMRVYCGPNPSCLVQSSSLSNAHIDYTTKPAIIFRIAARNEKGYGPATQVRWLQETSKDGSAAKPAAKRPVSSPDMKGAGPKKARSDQ-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V4C8-1", "uniprot_id": "HCF_DROME", "id": "Q9V4C8-1", "name": "Host cell factor", "aln": "MEGSDFVDPAFSSGERISASDLNSEHIIQAENHSFANRISMDMDVPDGHQLDSNLTGFRWKRVLNPTGPQPRPRHGHRAINIKELMVVFGGGNEGIVDELHVYNTVTNQWYVPVLKGDVPNGCAAYGFVVEGTRMFVFGGMIEYGKYSNELYELQATKWEWRKMYPESPDSGLSPCPRLGHSFTMVGEKIFLFGGLANESDDPKNNIPKYLNDLYILDTRGVHSHNGKWIVPKTYGDSPPPRESHTGISFATKSNGNLNLLIYGGMSGCRLGDLWLLETDSMTWSKPKTSGEAPLPRSLHSSTMIGNKMYVFGGWVPLVINDSK-STTEREWKCTNTLAVLDLETMTWENVTLDTVEENVPRARAGHCAVGIQSRLYVWSGRDGYRKAWNNQVCCKDLWYLEVSKPLYAVKVALVRASTHALELSWTATTFAAAYVLQIQKIEQPLNTSSKLLSNNIVQQGTPTSAETSGINISAN---RSGSALGLGVEATSTVLKLEKESLQLSG------------------------CQPETNVQPSVNDLLQSMSQPSSPASRADKDPLSSGGGTTFNLSTSVASVHPQISVISSTAAVTGNDTASPSGAINSILQKFRPVVTAVRTSTTTAVSIATSTSDPLSVRVPSTMSANVVLSSSSSTLRIVPSVTASHSLRIASSQASGNNCRSSSAINILKTALPNVAVQSQPTSSTTTSIGG-----------------------------------KQYFIQKPLTLAPNVQLQFVKTSGG---------------MTVQTLPKVNFTASKGTPPHGISIANPHLASGITQIQGSTVPGSQIQKPIVSGNVLKLVSPHTMAGGKLIMKN---SNILQMGKVTPNVMGGKPAFVITNKQGTPLGNQQIIIVTTGGNVRSVPTSTVMTSAGGSASGTNIVSIVNS----------TSTTPSPLQALS-------------------------------------------GQKTLISNQSGVKMLR------------------------------------------------------------------------------------------------------------------NISSVQASSSMAFGQKQSGTPIHQKTALYIGGKAVTVMS------------------------------------------------------------------------------------------------------------------TNTSMAASGNKVMVLPG--------------------TSSNNSPATTTALSARKSFVFNAGGSPRTVTLATKSINAKSIPQ---------------SQPVTETNNHSVATIKDTDPMDDIIEQLDGAGDLLKLSESEGQHG----------------------------SEENENNGENATSSSASALFTGGDTAGPSRAQNPIVMEHPVDIIEDVSGVSS---------------------------------------------TTDVNETAIVSGDTIESLKMSEKENDDVKSMGEKSILS----------------------------------------------------------------------------------------------------------------------DDCHQPTTSETEAATILTTIKSAEALVLETAEIR---------------------KDHTGCTIGSLKENQDENKKFKQRQE------------------------------------SSPSQNIHQFQNVDGSQLEALASAALLQAATSDTTALALKELIERPE--SETNTRSSNIAEIQQNNVQSTLAVVVPNTSQNENQKWHTVGVFKDLSHTVTSYIDSNCISDSFFDGIDVDNLPDFSKFPRTNLEPGTAYRFRLSAINSCGRGEWGEISSFKTCLPGFPGAPSAIKISKDVKEGAHLTWEPPPAQKTKEIIEYSVYLAVK---PTAKDKALSTPQLAFVRVYVGAANQCTVPNASLSNAHVDCSNKPAIIFRIAARNQKGYGPATQVRWLQDPAAAKQHTPTVTPNLKRGPEKSTIGSSNIANTFCSPHKRGRNGLHD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : *****:. :** *********: ****:*******************.****::*.::**:* ******** :***::*****:*******:******::***::: .::*..* .*********::**:* :*******:*:*******:****** *: * * * :* *** ********.: :: * . : .*:************** *: :::**.** ** *********:* * ***:*********::* * :* *:********* *:*::*:**.: :**:*:*:********:*.*:.***:************************..:* . :* ****.*::**:** *.. * :*:**:** : * ::: .. ..*... .* :* :. . *: : . . : : *.:. ..: : : .:*.: :. . .: . . : . **:* ::: **.:. *..: ::*. .. . :.*.. : .:* . * * : .*. :*.:::: : :.. . * : .... :. :::.* : .*: ..*. : *. :**. .*.... *::*.::.* . * ..:.:. . * . ::: .: *..* *. :: . *:::. * : .*:* : ** *: * *. * : .*:*. ::: * . :.. *: *:..: * :: .:.. *.: .:: .:*: :*. * ***: **.: . ::. *::.*. .*: . .* :. ..*.*. . : : :.: : .* .:.. : :: .. . .. ..* * * : *: : .. *:* **:: ..: . . * .* :. . .....:.: : : ..** * .. . .: .:* * *.::: ..* :: . . : . :. .: .:*.*::* :* :.:::*: *: .* : . ** : *:* : *:*: : *: . . : : *. :: *.*.* . . :: * . : : :. *:. : . :.. :::::*. **:.* . ** * . .*: . * . :**:.:: : :*.*****:**::.**:**** :.*:*:************.******. :********* : .: :*********:: . : *: :..****:*** *. .* * .:******:* :.************:*************:.: . : .. . .*: ", "identical_positions": 465, "similar_positions": 471, "identity": "21.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2412", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48722-1", "uniprot_id": "HS74L_MOUSE", "id": "P48722-1", "name": "Heat shock 70 kDa protein 4L", "aln": "MSVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNVRNTIHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSTGVKVRYLEEERPFAIEQVTGMLLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAYGIYKQDLPSLDEKPRNVVFIDMGHSAYQVSVCAFNKGKLKVLATTFDPYLGGRNFDEALVDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNRAQFEQLCASLLARVEPPLKSVMDQANLQREDINSIEIVGGATRIPAVKEQVTRFFLKDISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSVTLRWKTSFEEGTGECEVFSKNHPAPFSKVITFHKKEPFELEAFYTNLHEVPYPDPRIGNFTIQNVFPQSDGDSSKVKVKVRINIHGIFSVASASVIEKQNLEGDHNDAAMETEAP-KSEGK-EDVDKMQVDQEEGGHQKCHAEHTPEEEIDHTGAKAKAPPSDKQDRINQTIKKGKIKSIDLPIQSSLYRQLTQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDKLGTVYEKFITPEDMNKLSAMLEDTENWLYEEGEDQPKQVYVDRLQELKKYGQPIQMKYVEHEERPKALNDLGKKIQLVLKVIEAHRNKDERYDHLDPAEMERVEKYISDSMNWLNSKMNAQNKLSLTQDPVVKVSEIVTKSKELDNFCNPIVYKPKPK-VEAPEDKAKTGSEHNGPMDGQSGSETSPDPPKGSSQHTDS-GEMEVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95757-1", "uniprot_id": "HS74L_HUMAN", "id": "O95757-1", "name": "Heat shock 70 kDa protein 4L", "aln": "MSVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNVRNTIHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGMLLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAYGIYKQDLPPLDEKPRNVVFIDMGHSAYQVLVCAFNKGKLKVLATTFDPYLGGRNFDEALVDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNRAQFEQLCASLLARVEPPLKAVMEQANLQREDISSIEIVGGATRIPAVKEQITKFFLKDISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSITLRWKTSFEDGSGECEVFCKNHPAPFSKVITFHKKEPFELEAFYTNLHEVPYPDARIGSFTIQNVFPQSDGDSSKVKVKVRVNIHGIFSVASASVIEKQNLEGDHSDAPMETETSFKNENK-DNMDKMQVDQEEG-HQKCHAEHTPEEEIDHTGAKTKSAVSDKQDRLNQTLKKGKVKSIDLPIQSSLCRQLGQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDRLGTVYEKFITPEDLSKLSAVLEDTENWLYEDGEDQPKQVYVDKLQELKKYGQPIQMKYMEHEERPKALNDLGKKIQLVMKVIEAYRNKDERYDHLDPTEMEKVEKCISDAMSWLNSKMNAQNKLSLTQDPVVKVSEIVAKSKELDNFCNPIIYKPKPK-AEVPEDKPKANSEHNGPMDGQSGTETKSDSTKDSSQHTKSSGEMEVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WBR5-1", "uniprot_id": "X1WBR5_DANRE", "id": "X1WBR5-1", "name": "", "aln": "MSVVGIDVGFQNCYIAVARSGGIETIANEYSDRCTPACISLASKNRTIGNAAKSQIITNFKNTVHGFKKFHGRAFDDPFVQGEKSRLPYSLHKLDNGNAGIKVRYLNEDKVFTIEQVTAMLLTKLKETSEHALKKPVVDCVISVPSFFTDVERRSVMDATQIAGLNCLRLINDTTAVALAYGIYKQDLPNPEEKPRNVVFVDIGHSSYQVAIASFNKGKLKMLATAFDPYLGGRNFDEILVEYFCEDFKNRFKLNVKDNPRALLRLYQECEKLKKLMSANSSDLPLNIECFMNDIDVHGKLNRTQFEEMCSQLMMRVEAPLRSVMEQSKLSRDEIYAIEVVGGATRMPAIKERISKFFGKDTSTTLNADEAVARGSALQCAILSPAFKVREFSITDTVPFPITLRWKSPTDESVGECEVYSKNHPAPFSKIITFHKKEPFDLEAFYSCPHDLPYPDVRIGRFSVQNVVPQPDGDSSKVKVKVRVNVHGIFSVSSASLIEKQ--KGEPEDVQMDTEPTVQNEGRPEEQSKMQVDQEGQGEQPSEEERANNSGIKDGDKQDQGASSSK--------AKSKVKSVDLPILANTTRQLDRDVLTHFVEYEKKMIIQDKLEKERNDAKNGVEEYVYDLRDKLCGIYEKYVTEDESNRLTIMLEDTENWLYEEGEDQDKEIYQHKLAELKKYGEPIEERYREHEGRPRAFDELGKKLQLFMKVVDMYRDKDERYEHLSAEDMGVVEKSVNEALGWMNTKMNAQSKLSFAQDPAVKVADIIQKIQELEDVCNPILNRPKPKTEELVEEGDKSDGAHNGPT-AQQGADS-----KGNQQTKPPSGEMDVD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******:** ******************************.*:.*:*********:**.:**:*****:***:****:** *: ****.*:*: **.:*:*****:*:: *:*****.***:*******:******.*****:******.****** *:*:********:*:**************** :********:*:***:*** :.:*******:***:************ **:***::**.::*:***:*.********************:*************:** .*:**:***::*:.*: ***.**::**:*::*.*::* :**:******:**:**::::** ** *************.******************** **:.:*****:. ::. *****:.*********:*********:*****: *::**** *** *::***.**.************:*:******:***:**** :*: .*. *:**.. :.*.: :: .******* .* .. *:: :. *.. . : :.. *.* *.*:**:**** :. *** :*:*. ::* * ***:*************.*******:**:* :***::* :: .:*: :**********:**** *::* .:* ******:**: :* *** **:*:::****:**.:**:: :*:*****:**.. :* *** :.:::.*:*:*****.***::***.***::*: * :**::.****: :**** * *: *:.. **** .*.*::: *...* . . ***:**", "identical_positions": 537, "similar_positions": 213, "identity": "63.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2415", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P41350-1", "uniprot_id": "CAV1_RAT", "id": "P41350-1", "name": "Caveolin-1", "aln": "MSGGKYVD---SEGHLYTVPIREQGNIYKPNNKAMA-DEVNEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSTIFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPLFEAIGKIFSNIRISTQEEI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49817-1", "uniprot_id": "CAV1_MOUSE", "id": "P49817-1", "name": "Caveolin-1", "aln": "MSGGKYVD---SEGHLYTVPIREQGNIYKPNNKAMA-DEVTEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSTIFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPLFEAIGKIFSNIRISTQKEI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03135-1", "uniprot_id": "CAV1_HUMAN", "id": "Q03135-1", "name": "Caveolin-1", "aln": "MSGGKYVD---SEGHLYTVPIREQGNIYKPNNKAMA-DELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6YLH9-1", "uniprot_id": "Q6YLH9_DANRE", "id": "Q6YLH9-1", "name": "Caveolin", "aln": "MTSG-YKDGTPEEEYAHSPFIRKQGNIYKPNNKEMDNDSINEKTLQDVHTKEIDLVNRDPKHLNDDVVKVDFEDVIAEPAGTYSFDGVWKASFTTFTVTKYWCYRLLTALVGIPLALVWGIFFAILSFIHIWAVVPCVKSYLIEIHCISRVYSICVHTFCDPLFEAMGKCFSNVRVTATKVV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.* * * .* : :: **:********** * *.:.** : *.*********************:********* **:****:************** ****:::.***:**:***:******:********:**:****:******** ***.*******:** ***:*:. : :", "identical_positions": 128, "similar_positions": 33, "identity": "70.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2416", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHY1-1", "uniprot_id": "JAM1_RAT", "id": "Q9JHY1-1", "name": "Junctional adhesion molecule A", "aln": "MGTEGKAGSKLLFLFT-SMILGSLVQGKGSVYSPQTAVQVPENDSVKLPCIYSG-F-SSPRVEWKFVQG-STTALVCYNNQITVPYADRVTFSSSGITFSSVTRKDNGEYTCMVSEDGGQNYGEVSIHLTVLVPPSKPTVSIPSSVTIGNRAVLTCSEHDGSPPSEYSWFKDGVPMLTADAKKTRAFINSSYTIDPKSGDLVFDPVSAFDSGEYYCEAQNGYGTAMRSEAVRMEAV--------------ELNVGGIVAAVLVTLILLGLLIFGIWFAYSRGYFERTKKG---TAPGKKVIYSQPSARSEGEFKQTSSFLV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88792-1", "uniprot_id": "JAM1_MOUSE", "id": "O88792-1", "name": "Junctional adhesion molecule A", "aln": "MGTEGKAGRKLLFLFT-SMILGSLVQGKGSVYTAQSDVQVPENESIKLTCTYSG-F-SSPRVEWKFVQG-STTALVCYNSQITAPYADRVTFSSSGITFSSVTRKDNGEYTCMVSEEGGQNYGEVSIHLTVLVPPSKPTISVPSSVTIGNRAVLTCSEHDGSPPSEYSWFKDGISMLTADAKKTRAFMNSSFTIDPKSGDLIFDPVTAFDSGEYYCQAQNGYGTAMRSEAAHMDAV--------------ELNVGGIVAAVLVTLILLGLLIFGVWFAYSRGYFERTKKG---TAPGKKVIYSQPSTRSEGEFKQTSSFLV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y624-1", "uniprot_id": "JAM1_HUMAN", "id": "Q9Y624-1", "name": "Junctional adhesion molecule A", "aln": "MGTKAQVERKLLCLFILAILLCSLALGSVTVHSSEPEVRIPENNPVKLSCAYSG-F-SSPRVEWKFDQG-DTTRLVCYNNKITASYEDRVTFLPTGITFKSVTREDTGTYTCMVSEEGGNSYGEVKVKLIVLVPPSKPTVNIPSSATIGNRAVLTCSEQDGSPPSEYTWFKDGIVMPTN-PKSTRAFSNSSYVLNPTTGELVFDPLSASDTGEYSCEARNGYGTPMTSNAVRMEAV--------------ERNVGVIVAAVLVTLILLGILVFGIWFAYSRGHFDRTKKG---TSS-KKVIYSQPSARSEGEFKQTSSFLV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JHH1-1", "uniprot_id": "A0AC58JHH1_DANRE", "id": "A0AC58JHH1-1", "name": "Junctional adhesion molecule A", "aln": "---------MLTFAFVCFSLFVTGIHGFQVTVTSP--VKVKENEGVDLQCSYTSDFGATPRVEWKFKDLKGSQTLVYFDGKPTGQYTGRVTMYDKGLRFNKVTRADTGDYDCEVSGSGG--YGENTIKLTVLVPPAKPVSRIPSSVTTSSNVRLTCFDPVGSPPSTYKWYKDNTPLPED-PTKFPAFKNLTYKMNVFNGNLEFPSVSKMDTGSYFCEASNGEGVPQRGDEVKMEVLMSSCRGPCRSSIQGDLNVGGIVAGVIVALLAVGLLLFGLWYASKKGYLPKNRNRKLFIHSLRQMMWMRLMDSDRNHLLWCSLCSSE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * :: : * . :. *:: **: :.* * *:. * ::******* : .: ** ::.: * * .***: .*: *..*** *.* * * ** .** *** .::* *****:**. :***.* .... *** : ***** *.*:**. : ... ** * :: :: .*:* * .:: *:*.* *:* ** *.. .: .:*:.: : *** ***.*:*:*: :*:*:**:*:* .:*:: :.:: . ::::: : ....: * ", "identical_positions": 96, "similar_positions": 100, "identity": "29.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2421", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A081-1", "uniprot_id": "D4A081_RAT", "id": "D4A081-1", "name": "Histone-lysine N-methyltransferase SETDB1", "aln": "------------------------------------------------------MVLGVFKSQLSTGK------QNSGESMSSLPGCMSLAAAPAAADSA-------EIAELQQAVVEELG----------------ISMEELRQFIDEELEKMDCIQQRKKQLAELETWVLQKESE--------------------------------------------------VAYVDRLFDDAS-----------------------------------------------------------------------------------------------------REVTNCESLVKDFYSKLGLQYHDSSSDDEASQPT------------------------------------------EIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDLHKG---------------------------------------------------------------------------------------TLGQVSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGLGK-----KYKVKFDNK---GKSLLSGNHIAYDYHPPADKLFVGSRVVAKYK---------DGNQVWLY-AGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDSSCRDFIEEYITAY-PNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDK-RCEWIYRGSTRLEPMFSMKTSSASAMEKKQGGQLRTRPNMGAVRSKGPVVQYTQDLTSTGIQFKPMEPLQPIVPPAP--LPMLPLSPQAGDSESLESQLAQSRKQVAKKSTSFRPGSVSSGHSSPTSPTLSENVPPGKIGMNQTYRSPSASVTSTPAPAAPSGPPAPPGPLAPPGPPAPPAFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRIRPMRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLYLEMFCLDPYVLVDRKFQP----FKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTVQATACTPGGQINPSSGYQHKRLEECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDVPSSSDSSGVDMKDQEDGNSGSEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKESELSEVTSKDSRAPDRGPPHVPITPSGSVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSRSSFKTSEGGDGRAGGGRGEAERASTSGLSFKDEGDSKQSKKEDPEDRNKMSVVTEGSQNHGHNP-PMKSEGLRRPASKISMLQSQRVVTSTQSNPDDILTLSSSTESEGESGTSRKPTTGQTSATAVDSDDIQTISSGSDGDDFEDKKNLSGPTKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15047-1", "uniprot_id": "SETB1_HUMAN", "id": "Q15047-1", "name": "Histone-lysine N-methyltransferase SETDB1", "aln": "--------------------------------------------------------------------------------MSSLPGCIGLDAATATVESE-------EIAELQQAVVEELG----------------ISMEELRHFIDEELEKMDCVQQRKKQLAELETWVIQKESE--------------------------------------------------VAHVDQLFDDAS-----------------------------------------------------------------------------------------------------RAVTNCESLVKDFYSKLGLQYRDSSSEDESSRPT------------------------------------------EIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDLHKG---------------------------------------------------------------------------------------TLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGK-----KYKVKFDNK---GKSLLSGNHIAYDYHPPADKLYVGSRVVAKYK---------DGNQVWLY-AGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAY-PNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDK-RCEWIYRGSTRLEPMFSMKTSSASALEKKQG-QLRTRPNMGAVRSKGPVVQYTQDLTGTGTQFKPVEPPQPTAPPAPPFPPAPPLSPQAGDSD-LESQLAQSRKQVAKKSTSFRPGSVGSGHSSPTSPALSENVSGGKPGINQTYRSPLGSTASAPAPSA------------LPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCLDPYVLVDRKFQP----YKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCSSDSSGVDLKDQEDGNSGTEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGPPHIPVPPSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSSFKTNEGGEGRAGGSRMEAEKASTSGLGIKDEGDIKQAKKEDTDDRNKMSVVTESSRNYGYNPSPVKPEGLRRPPSKTSMHQSRRLMASAQSNPDDVLTLSSSTESEGESGTSRKPTAGQTSATAVDSDDIQTISSGSEGDDFEDKKNMTGPMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1L8U8-1", "uniprot_id": "STB1A_DANRE", "id": "Q1L8U8-1", "name": "Histone-lysine N-methyltransferase SETDB1-A", "aln": "MSREKDDENLLRMTKDDLQRWIQAEVERNPHL-MQRREQLAQVEEWVKQKERDSTCTRLLYSNACESV------LECESVMKGLYALLGLDYRDEDSEEEGGGGQPHDVIQIADDEAERRGNVICNGEDDDNDDLVVIDLGATKETLEPMLEKVTVAIQKSSKLVQDLVQMVSKTSMGATSPLSTSSSDINRPSSSSTPEIVRPESVTPKLEITNSITIVKTESLSSVPKISSLFNSSEQCKSIADHDSYFKPTIKTEPEWTPLTPWEDSESSPFEKLIKTESQSTDVTPSVMTPNKQPELLSFQSTTKIKPEPQSTQANTELSSPPSNSKLLENHNSLSIAAIKNESQLKASVSEVDLLESDSEQSDNAATKTRFKPSEVTASSKLKSSGDHNSASASLNRTDPKVRPVTPSGTPPPSKSPPAVDNTASVETNQTDSELPTETPVEESTLPSNPKEAVIMSDAESTDKTEKPQTRKKSSKPSVTTTSPESRLTSSKSPPVTKTSSTQKETARAQSPSDSIDESADMEDSPDEPSNSPTESPTKTPDKTTRNDAPAKPSKAKKSSKHSSSESSKTLKEIKLKVGAAVLGKKRHNHWSRGTVQEVETEDDGN-----TYKVEFKKG---KTIVLSANHVAAYKPPSLKDLYIGCRVVASAK---------SENGKSLYNAGVMVELPERKNRMRFLVFFDDGLATYLALPDLYFVCKQTKKVWREIKDESSRKQVKDYLQVY-PNPIAVVLRLGQETKAVRNGQFEDCTVLQLDGSLVQICYKNDK-QKEWIYKGSDKLEHILTIKN------RHKQHSHKKHHSPEGKTQSSQPKTLHSSKSASTSTSSANVSPVSSDS-----------------------VSPARVTRQSDKTKTSISPQKIMSPAFQPKVVLQKISLPSSISPAARVSNSNTNSSLIS------------------AKRPAPDEEEDEYFSEDEVEVLEQEQNKSVYLHQRCCPACLEEVRPHQVDIHHGKNPLLIPLLFKFRRMTARRRIDGKLFFHIFYRSPCGRSLCDMQEVQDYLFETRCDFLFLEMFCMDPFVLVNRARPPSTTTGQPHLYLPDISEGKEVMPVPCVNEVDNTLAPNVTYTKDRVPARGVFINTSSDFMVGCDCTDGCRDRSKCACHKLTIEATSLCTGGPVDVSAGYTHKRLPTSLPTGVYECNPLCRCDPRMCSNRLVQHGMQLRLELFMTQHKGWGIRCKDDVPKGTFVCVFTGKIVNEDKMNEDDTMSGNEYLANLDFIEGVEKLKEGYESEAYCS--------------------------DTEVESSKKTITMKTGPLLKNSLYKEDSSSGEE----------------------------------PMEVDTAKDKVK----------------------------------------------VHDKPLGERKLPNKPHETPKDTQKKISELRKNDGQES-----SGPKRCFAIKSFQRRVKPLESTEAQK--------------------------------------------------------------------------------------------EKTKTPKNTRGLFNDEDACYIIDARQEGNLGRYINHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIKAGTELTWDYNYEVGSVEGKVLLCCCGSLRCTGRLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q32KD2-1", "uniprot_id": "SETB1_DROME", "id": "Q32KD2-1", "name": "Histone-lysine N-methyltransferase eggless", "aln": "MSGQPTAVDCLESSGSTVEDVQETPASREKSYGLPVRKGENSLESPAEQAAKDVEIEELTHSEAIAATGSTRKQCPYGGKAPDEPGKLADESEDRKGENTKAIASSPVLVAVDSDSSVELIESPVKFSSANESEKDPPKPDAVNEAAAKEAEEMTDSSISSPTSESFPEKDEKTNKENEQEPPGMEVDQDVEESISRPAEEYKIEN---TLKGHKRISLTEIEEHKIVDKKDDVLEVELEKG-------------------------------TAPKAAEDEKLNALLSDGDVFYDKECVNCNCTKLHKQYVLANMATLNFYQVLRKSSKQQFLCMGCHDTAMDLYEEYAGQLMAKQPLLLKDFHQDHADFVALDSSDEEEEE---------------------------------KQPEKSDFSKNKLQLIEDELDDAIKNVLNKVDFTAQLSWSKTILQAKADHLERQFALADVELEKVQTTADKMHCALYN---------------------------------------------------SCPVAHKHLPTLDIEPSDYVHEVPPPGEIVRPPIQLGETYYAVKNKAIASWVSIKVIEFTESTAINGNTMKSYKIRYLNTPYQMIKTVTAKHIAYFEPPPVR-LTIGTRVIAYFDGTTLSRGKDKGVVQSAFYPGIIAEPLKQANRYRYLIFYDDGYTQYVPHRDVRLVCQASEKVWEDVHAAS-RDFIQKYVEKYSVDRPMVQCTRGQSMTTESNGTWLYARVIDIDCSLVLMQFEGDKNHTEWIYRGSLRLGPVFRETQN---------NMNSSSAQQLRVPRRTEPFIRYTKEMESS-------------------------------------SKVNQQMRAFARKSSASAQNNALAAASSAATPAGGRTNAGGVSTSNSASAVRHLN-----------------------NSTIYVDDENRPKGHVVYFTAKRNLPPKMYKCHECSPNCLFKIVHR----LDSYSPLAKPLLSGWERLVMRQKTKK----SVVYKGPCGKSLRSLAEVHRYLRAT-ENVLNVDNFDFTPDLKCLAEYSID----PSIVKDTDISKGQEKMAIPLVNYYDNTLPPPCTYAKQRIPTEGVHLNLDEEFLLCCDCEDDCSDKSKCACWQLTVAGVRYCNPKKPIEEIGYQYKRLHEHVPTGIYECNSRCKCK-KNCLNRVVQFSLEMKLQVFKTSNRGWGLRCVNDIPKGAFICIYAGHLLTETMANEGGQDAGDEYFADLDYIEVAEQLKEGYESEVDHS--------------------------DPDAEEDNGGPDAEDDDDFRPNYHYQR-------------------------------------------------------------------------------------------------------------KIKRSSRSGSTQNSSTQSSELDSQER------------AVINFNPNADLDETVRENS----------------------------------------------------------------------------------------------------VRRLFGKDEAPYIMDAKTTGNLGRYFNHSCSPNLFVQNVFVDTHDLRFPWVAFFSAAHIRSGTELTWNYNYEVGVVPGKVLYCQCGAPNCRLRLL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :. :. : : . . . .. *:: . . .. . * . ::: *. :: * * ... : . .: .: .: .. . : . : : :: . . .* : :* * .: . : .**:.: : ::.:*:* *. * :* **:* . . : .*::.* : *: *:*:*:*** : *:. :: :*: :*.*.::. * *. ::.*: * : * ** .: :* : . * ::* *** : : .** : ****:** :* :: . : : . * ::.. .: . : : :..:: . : .. . . . . . . .. . .* : *. ** .: . .** *** :.*:. *:: . :.*: *** .* : *:. ** * :.* :: * : * : . **: *:* :.:. ** *.* .* :*:*:*:* .**.:* . :*:: *** *.* *:***** :**: .. . ** :*** :***:**** *:*. . * **:**..::::*::* *.::***:** :*:.**:*:*:::*:::.: :: . *:**:*:**.** .*::******:. * *.. :. . . : . * .. . :: . . : : .: :.. : .* ::. ::: **:**: ******:****************************:: :*::******:****** * ** * * **: .* ***", "identical_positions": 221, "similar_positions": 285, "identity": "12.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2422", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P31503-1", "uniprot_id": "PO2F1_RAT", "id": "P31503-1", "name": "POU domain, class 2, transcription factor 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------LTPAQQQLLLQQAQAQAQLL------------------AAAVQQHSASQQHSAAG---------------------------------ATISASAATP----------------------------------------------MTQIPLSQPIQIAQDLQQLQQLQQQNLNLQQFVLVHP----TTNLQPAQFIISQTPQGQQGLLQAQNLLTQLPQQSQANLLQPQPS--ITLTSQPTTPTRTIAATPIQTLPQSQTTPKRIDTPSLEEPSDLEELEQFAK----TFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKN----MCKLKPLLEKWLND---AENLSSDSTASSPSALNSPGLGAEGLNRRRKKRTSIETNIRVALEKSFME-NQKPTSEDITLIAEQLN---MEKEVIRVWFCNRRQKEKRINPPSSGGTSSSPIKAIFPSPTSLVATTPSLVTSSTATTLTVNPVLPLTSAAMTNLSLT------------------------GTTDSTSNN-TATVISTAPPASSAVTSPSLSPSPSAS-ASTSEASSASETSTTQTTS-TPLPSPLGASQVMVTASGLQTAAAAALQGAAQLPANASLAAMAAAAGLNPGLMAPSQFAAGGALLSLNPGTLGGALSPALMSNSTLATIQ----ALASSGSLPITSLDATGNLVFAN---AGGAPNIVTAPLFLNPQNLSLLTSNPVSLVSAAAASTGNSAPTASLHASSTSTESIQNSLFTVASASGAASTTTAASKAQ--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P25425-1", "uniprot_id": "PO2F1_MOUSE", "id": "P25425-1", "name": "POU domain, class 2, transcription factor 1", "aln": "------------------------MNNPSETNKSSMESEDASTGTQTNGLDFQKQPVPVGGAISTAQAQAFLGHLHQVQLAGTSLQAAAQSLNVQSKSSEESGDSQQSSQPSSQPPSVQSAIPQTQLMLAGGQITGLTLTPAQQQLLLQQAQAQAQLL------------------AAAVQQHSASQQHSAAG---------------------------------ATISASAATP----------------------------------------------MTQIPLSQPIQIAQDLQQLQQLQQQNLNLQQFVLVHP----TTNLQPAQFIISQTPQGQQGLLQAQNLLTQLPQQSQANLLQPQPS--ITLTSQPTTPTRTIAAASVQTLPQSQSTPKRIDTPSLEEPSDLEELEQFAK----TFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKN----MCKLKPLLEKWLND---AENLSSDSTASSPSALNSPGLGAEGLNRRRKKRTSIETNIRVALEKSFME-NQKPTSEDITLIAEQLN---MEKEVIRVWFCNRRQKEKRINPPSSGGTSSSPIKAIFPSPASLVATTPSLVTSSTATTLTVNPVLPLTSAAVTNLSLTDQDLRRGCSWEVLRSLPDRVTTTAGTTDSTSNNNTATVISTAPPASSAVTSPSLSPSPSAS-ASTSEASSASETNTTQTTS-TPLPSPLGASQVMVTTPGLQT-AAAALQGAAQLPANASLAAMAAAAGLSPGLMAPSQFAAGGALLSLSPGTLGSALSPALMSNSTLATIQ----ALASSGSLPITSLDATGNLVFAN---AGGAPNIVTAPLFLNPQNLSLLTSNPVSLVSAAAASTGNSAPTASLHASSTSTESIQSSLFTVASASGPASTTTAASKAQ--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14859-1", "uniprot_id": "PO2F1_HUMAN", "id": "P14859-1", "name": "POU domain, class 2, transcription factor 1", "aln": "------------------------MNNPSETSKPSMESGDGNTGTQTNGLDFQKQPVPVGGAISTAQAQAFLGHLHQVQLAGTSLQAAAQSLNVQSKSNEESGDSQQPSQPSQQP-SVQAAIPQTQLMLAGGQITGLTLTPAQQQLLLQQAQAQAQLL------------------AAAVQQHSASQQHSAAG---------------------------------ATISASAATP----------------------------------------------MTQIPLSQPIQIAQDLQQLQQLQQQNLNLQQFVLVHP----TTNLQPAQFIISQTPQGQQGLLQAQNLLTQLPQQSQANLLQSQPS--ITLTSQPATPTRTIAATPIQTLPQSQSTPKRIDTPSLEEPSDLEELEQFAK----TFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKN----MCKLKPLLEKWLND---AENLSSDSSLSSPSALNSP--GIEGLSRRRKKRTSIETNIRVALEKSFLE-NQKPTSEEITMIADQLN---MEKEVIRVWFCNRRQKEKRINPPSSGGTSSSPIKAIFPSPTSLVATTPSLVTSSAATTLTVSPVLPLTSAAVTNLSVT------------------------GTSDTTSNN-TATVISTAPPASSAVTSPSLSPSPSAS-ASTSEASSASETSTTQTTS-TPLSSPLGTSQVMVTASGLQTAAAAALQGAAQLPANASLAAMAAAAGLNPSLMAPSQFAAGGALLSLNPGTLSGALSPALMSNSTLATIQ----ALASGGSLPITSLDATGNLVFAN---AGGAPNIVTAPLFLNPQNLSLLTSNPVSLVSAAAASAGNSAPVASLHATSTSAESIQNSLFTVASASGAASTTTTASKAQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U124-1", "uniprot_id": "A0AB32U124_DANRE", "id": "A0AB32U124-1", "name": "POU domain protein", "aln": "------MADGGAASQDESSGPDSRMSNPSETSKCAMESGDENTGAQTNGLDFQRQTVQTTSAITNAHAQALL--------------------------------------------------------------QQLTLTPAQQQLLLQ--QAQAQLL------------------AAAVQ-HSAGQQSSTTG---------------------------------ASISASAATP----------------------------------------------ITQIPLSQPIQITPQLLQ-QQQQQQNLNLQQFVLVQPGHPIATQLQPAQFIISQTPQGQQSLLQAQNLLTQLPQ-SQANLLQTQPS--ITLATQPATPTRTIAATPIQSLAHTQTTPKHMDTPSLEEPSDLEELEQFAK----TFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKN----MCKLKPLLEKWLNDAVCAENQTSDQALSSPSSLGSPGLGMEGLNRRRKKRTSIETNIRVALEKSFLEQNQKPTSEEITMIADQLN---MEKEVIRVWFCNRRQKEKRINPPNNGSAASTPIKAIFSPTTTLVPSTASLITSNTPTTMTVNPVLPLTSTSVSGISFT------------------------GTTLGSAINNTASVISTAPAATTASSSPSLSPSPTAVQTSSSEQASAQETLTAVSQAPSSLASTLGTGQVMVAAP----SLSAALQGAAQLPTSASIAAMAAAAGLNPGLMASSQFAPGGALLSLAPGGLGSALSPALMSNSTLATIQGVWSALASSGTLPITSLDGSGNLLFANT-SAGSTPNLVTAPLFLNPQNLSLLASNPVSLVSAGGAAG--AAGALNLHFTADAHQS------AVTTATMPASTITTASKAQ--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VK71-1", "uniprot_id": "PDM2B_DROME", "id": "Q9VK71-1", "name": "POU domain protein 2, isoform B", "aln": "MPLLLATTLANNSHHQHLSTTATETAAAAATAKAAATAAAAATATMLLTSPTAATHCLAAATSAAGVNVQITGQGVSATLNDDQLQLPANYAANVGHLNGFNPKDNCPPVPPTSERAFEGLLRLPQIQVKQEFMESPPERPSCHPMNHQQAPANSALATSCRGKTILNPWYLRPADGIGYHNYNSNNNNSGSGEINKDVSQQMTSACGGSDGQTCLPVSYFGMETLASVKQRQKSLPDFLIPLHEIMFQQQHHYQQRTMGTLINSLPPGLVGYPPQKTETFKSLTPPKALQHHQNNQNHQIPQNHTGDHSFVRHFHERDRLIREHQLKHQQLRDVEEVLQEQEQDEEQEHETLRKPHVVPSELEHNHHWHGVVCDANGHATRLLHIAPPRAGPTPLPTHQQPPVGEVLPPNSTSFSTIVDPPKEPSIYEQPAPNGRHCRPANKVMRHMSNSPTPPSPLRSLSDCGKSFEEEELELGENCEMPQNLSSK---RQARELDSELENEVLDLAPPPKRLAEEQEEEKVASVNPPQPVAFAPEEMHQALQLQLHSYIEMVRQLAPEAFPNPNLATQFLLQNSLQALAQFQALQQMKQQQREDPLPSYSTPLAKSPLRSPSLSPVPRHSKSQQRTPPNSMTANSLGMSS-------------------AVMTPNTPSMQQQPQLQQSTPKPTSGLTVASAMAKLEQSPEETTDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKL-----YGNDFSQTTISRFEALNLSFKNMCKLKP-LLQKWLEDADSTVAKSGGGVFNINTMTSTLSSTPESILGR---RRKKRTSIETTVRTTLEKAFLMNCKPTSEEISQLSERLNMDKEVIRVWFCNRRQKEKRINPSLDLDSPTGTPLSSHAFGYPPQALNMSHMQMEGGSGSFCGSSISSGE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P31368-1", "uniprot_id": "PDM1_DROME", "id": "P31368-1", "name": "Protein nubbin", "aln": "---------------------------------------------MVMS------------------------------------ELRWHTAS---------PEDN-------------------KNSLKRDLLKSTPTSAREAAVHIMQNRYISRLS--------------RSPSPLQSNASDCDDNNSSVG----------------------------------TSSDRCRSP-----------------------------------------------LSPALSLSHQQAKRQLMSLQPHPAHHHHNPHHLN--------HLNHHQYK------QEEDYDDANGGALN---------LTSDNSRHSTQSPSNSVKSATASPVPVISVPSPVP----PMISPVLAPSGCGSTTPN------SMAAAAAAAAAVASTMGSGISPLLALPGMSSPQAQLAAAG---------LGMNNPLLTGSLSP---QDFAQFHQLLQQRQVALTQQFNSYMELLRSGSLGLAQDDPALTAQVAAAQFLMQSQLQALSQASQQLQ-----------ALQKQQQRQVDEPLQLNHKMTQQPRSSTPHSIRSPIAIRSPASSPQQLHHHHHHPLQITPPS--SAASLKLS--------------------GMLTPSTPTSGTQMSQGTTTPQPKTVASAAAARAAGEPSPEETTDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKL-----YGNDFSQTTISRFEALNLSFKNMCKLKP-LLQKWLDDADRTIQATGG-VFDPAALQATVSTP--EIIGR---RRKKRTSIETTIRGALEKAFLANQKPTSEEITQLADRLSMEKEVVRVWFCNRRQKEKRINPS--LDSPTGADDDESSY--------MMH-------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : * : ...:: * * : . : . : : * : . . :*: * :: : : * : . : .. : . . . : *.. :: . . : : :. : . : : . : .. .. : . . : :: . : . ** : :.. : . . . : :. . .. . .. : *. *. .: ::* ..: : .: . .::: . .: .: . * . * : : . :. :: .* :: . *.* *: .. :: :. : :*.. : . :: * : .: * :. . :: * :: : : : .* . . .: : . ", "identical_positions": 24, "similar_positions": 152, "identity": "2.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2433", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AE48-1", "uniprot_id": "MIDN_RAT", "id": "D4AE48-1", "name": "Midnolin", "aln": "-----------MEPQPGGARSCRRGAPGGACELSTT--------------------------AESAAPMSLAIHSTTGTRYDLSVPHDETVEGLRKRLSQRLKVPKERLALLHKDTRLSSGKLQEFGVGDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQPPATPGPGRAAGGGFRKYRLILFKRPWHRQGPQSPERGGERPQVSDFLSGRSPLTLALRVGDHMMFVQLQLAAQHAP---------------------------------------------LQHRHVLAAAAA---------AAAAARGDSSIAT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------PVSSPCRP----VSSAARVPPVSSSPSS--------------PVSPSP---------------------------------------------------------------------------------------------------------------------------------------------------VTAGTFQSHAASTTCPEQTDCSPP------------------------------------------------------------------------------------ASS------NTTSTPGSS--PTPRSRKPGAVIESFVNHAPGVFSGTFSGTLHPNCQDSSGRPRRDIGTILQILNDLLSATRHYQG--------------------------------------------------------MPASLTQLRCHAQCS-PASPAP----------DLTPKTTSCEKLATP---SLLQGQS-----------QIRMCKPPGDRLR---------QTENRATRCKVERLQLLLQQKRLRRKARRDARGPYHWTPSRKAGR---------------------------------------------------SDSSSSGGGGSPSEATGLGLDFEDSVWKPEVNPDIQSEFVVA------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TPJ7-1", "uniprot_id": "MIDN_MOUSE", "id": "Q3TPJ7-1", "name": "Midnolin", "aln": "-----------MEPQPGGARSCRRGAPGGACELNTA--------------------------TESAAPMSLAIHSTTGTRYDLSVPHDETVEGLRKRLSQRLKVPKERLALLHKDTRLSSGKLQEFGVGDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQ-------------------------------------------VSDFLSGRSPLTLALRVGDHMMFVQLQLAAQHAP---------------------------------------------LQHRHVLAAAAA---------AAAAARGDSSVAT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------PVSSPCRP----VSSAARVPPVSSSPSS--------------PVSPSP---------------------------------------------------------------------------------------------------------------------------------------------------VTAGSFRSHAASTTCPEQMDCSPP------------------------------------------------------------------------------------ASS------SSTSTPGSS--PTPRSRKPGAVIESFVNHAPGVFSGTFSGTLHPNCQDSSGRPRRDIGTILQILNDLLSATRHYQG--------------------------------------------------------MPPSLTQLRCHAQCS-PASPAP----------DLTPKTTSCEKLAATSSTSLLQGQS-----------QIRMCKPPGDRLR---------QTENRATRCKVERLQLLLQQKRLRRKARRDARGPYHWTPSRKAGR---------------------------------------------------SDSSSSGGGGGPSEATGLGLDFEDSVWKPEVNPDIQSEFVVA------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q504T8-1", "uniprot_id": "MIDN_HUMAN", "id": "Q504T8-1", "name": "Midnolin", "aln": "-----------MEPQPGGARSCRRGAPGGACELGPA--------------------------AE-AAPMSLAIHSTTGTRYDLAVPPDETVEGLRKRLSQRLKVPKERLALLHKDTRLSSGKLQEFGVGDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQ-------------------------------------------VSDFLSGRSPLTLALRVGDHMMFVQLQLAAQHAP---------------------------------------------LQHRHVLAAAAA---------AAAAR-GDPSIAS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------PVSSPCRP----VSSAARVPPVPTSPS---------------PASPSP---------------------------------------------------------------------------------------------------------------------------------------------------ITAGSFRSHAASTTCPEQMDCSPT------------------------------------------------------------------------------------ASSSASPGASTTSTPGAS--PAPRSRKPGAVIESFVNHAPGVFSGTFSGTLHPNCQDSSGRPRRDIGTILQILNDLLSATRHYQG--------------------------------------------------------MPPSLAQLRCHAQCS-PASPAP----------DLAPRTTSCEKLTAAPSASLLQGQS-----------QIRMCKPPGDRLR---------QTENRATRCKVERLQLLLQQKRLRRKARRDARGPYHWSPSRKAGR---------------------------------------------------SDSSSSGGGGSPSEASGLGLDFEDSVWKPEVNPDIKSEFVVA------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYU6-1", "uniprot_id": "MIDN_DANRE", "id": "Q6NYU6-1", "name": "Midnolin", "aln": "-----------MDQHP-SARSCSSRGAAPSCES-----------------------------VSGEPPMNLYIHSTTGTRFELSLPAEETVEGLKRRLSQRLKVPKERLALLHKETRLSSGKLQDLGITDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQ-------------------------------------------VSDFLSGRSPLTLALRVGDHMMFVQLQLAAQPSGG------------------------------------------PQLQHRHLISRGSSEGTTGLSHGASGSASGMARVSHN-----------------------------------------------------------------------------------------------------------------------------------------------------------------PHPHHPHQHPHHPNTTLPSNPAAFPPSPSIPSIPPMYSTSASGHCSPPPQPSQ---------------------------------------------------------------------------------------------------------------------------------------------------LPGSFLHSQQPSSACAPSPSSPSP------------------------------------------------------------------------------------AASCPEASCSAKTSGNCN--TPLRSRKPGAIIESFVNHAPGVFSGTFSGTLHPNCQDSTGRPRRDIGTILQILNDLLSATRHYQG--------------------------------------------------------MPPSLTQLRYQTQCTSPNSPAPSPPPSPPHTTGLTGLPTTVPSETQPTLHPLVQCQS-----------QIRMCKPPGDRLR---------QTENRATRCKVERLQLLMQQKRLRRKARRDSRAPYHWLPNRKAGR---------------------------------------------------SNSNSS----MSSEGS-LDLDFEDSVWKPDVKADMKSEFIMA------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8SXD4-1", "uniprot_id": "MIDN_DROME", "id": "Q8SXD4-1", "name": "Midnolin homolog", "aln": "MDKSAATNSATADGQNEAAAAAAAAATAAGCGSNNSSSTSSSNNTANSNNALQRLATTTSAVVASPMTINLNISTTTGGNFGVSVEPHISVESLKKIIAKKLKVAKDRICLLHREKELQDGTLRDHNLMDGSKIILIPNVETGLLAQR--PENTVMQALESLNDAQ-------------------------------------------VNDFLSGKTPLNLSMRLGDHMMLIQLQLSTVNPAGGGAATVAPVAGGASGSSINAAASTTSTVPVMPAGTGCSGANSTSLSSSAVLAAAAAGVGGSTGTSGSGTSSSSSSTSSSSSSSSSSSRTRSSGQRSSGRIGHGHVHSHQHPSLHAANWHGFSHGHGHGHSHGNGHGHHHHHHHHHHHHHHHHNASAVAAGSGGGMSSLRKMYGDLPSSSGASGSAPATGTGQSQSSSTLNGPDLTKLLIKGGIQNIVNSFALKDAGANARPVANGGSGSSPGKPVLEQSPIKSLSNLVSSPIKMTTIKNIPLPTTAATSSSSSCNCSSAAPSSSSSTSSGACATGGCQQDPIAAKLTSCLCTRLPTPSVAPPVATLVAPAPVARSGSTSSPSKCPESSCSGANAGFAARSTLAGTRVTFSGNSMLHKTGNNRITRTKHRHYHGQGHGHGHGNGHSSSSSSSSSSSSSHFFNHACAGNQPSVNAAAFATSSSSSSSSPSSSSSSPSKRRKLEQGMGAGAVGATAATATAAATVALPASTSATTAEPDDSLLGVSDTRTLAEASRNLTQTLRKLSKEVFTNKIDLSGAGVVSSGRSSSSGATSSGAASGEEAPRKSGSGAVIESMKNHGKGIYSGTFSGTLNPALQDRFGRPKRDISTVIHILNDLLSATPQYGRGARISFEAPTTGSVSGSGSGSGSSGSSSTTSSGSGLHHGSRSKMYSSKHHNCAKCNSRAQQQQQQSATLASGSGGSCSFRDCPSYHSSSAATKASTSSKSSSHSCCQTAEAPSSMTSQSNGCTCRYRRDDGQGEREREHTCQKCTVELANMKTRSKMDQLRLVMQQHKQKREARKLKSGPYATAASASAADSLSSIAAGGTAAVPMGAAAQYSAVSALVATPLQPAAVPVQTGKAAPANSITGNSSNANVNGNTSTAPATAATSAAAAPTAAPPSEVSPNHIVEEVDTAA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .* :. ... .* . .:.* * :*** .: ::: . :**.*:: ::::***.*:*:.***::..*..*.*:: .: ****: *:*.**:**::* **::********.::* *.*****::**.*::*:*****::****:: . *. ::: .:: .:.: . . : . * :. *.. ... . * . ** : .. : : .*::.. . ..... .:* .:.:: .. . *. .**:***: **. *::********:* ** ***:***.*:::********* :* .. * : : .: . .... . : .:: . : : * : * . *:* * : * **.*:::*:*::**:: :*:**: .** .. .*. .:*..: .* .. :. .. .::..:.:: ", "identical_positions": 129, "similar_positions": 191, "identity": "11.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2438", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KMM3-1", "uniprot_id": "OXR1_MOUSE", "id": "Q4KMM3-1", "name": "Oxidation resistance protein 1", "aln": "MSVS-NLSWLKKKSQSVDITAPGFN-PLGGAGKQAPQASKPPAPKTPIIEEEQNNSANTQKHPS-RKSELKRFYTIDTGQKK-TLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAVVTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTT-PDVAHPKEAPPASTVSG-IRPARVVSSTSEEEEAFTEKFLKINCKYITIGKGTVSGVLLVTPNNIMFDPHKTDPLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPIELDQLSGR-GSCHSKKATGVSAEDADPRARDQGNDSASTAPRSTEESLSEDAFTESELSPIREELLSS---EPRQEKSSDASSESVQTVSQMEVQSLTATSEAANVP-------DRTSSNPGALSHETGLSGLETATKGGDKATESLQEVSGPKEQSTEVKGQDNQDSSHQESSLQQEAGE-DSVSSGETVELKEKPAVLKDQQGQELKRDSETEVEELRKLWKTHSMQQAKQQRDTIQQVSQRESKHSSAAADAHGEGSSLLKEKRRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFIQWSPEIYAEDSGEYTREPGFIVVKKMDESEANEA--PAGEAAAREWEVVSVAEYHRRIDALNTEELRTLCRRLQITTREDINSKQVAPAKADLEPESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGTSLKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPFKVSDGFYGTGETFVFTFCPEFEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNHTLSKKEDFFIQDIEIWAFE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N573-1", "uniprot_id": "OXR1_HUMAN", "id": "Q8N573-1", "name": "Oxidation resistance protein 1", "aln": "MTKDKNSPGLKKKSQSVDINAPGFN-PLAGAGKQTPQASKPPAPKTPIIEEEQNNAANTQKHPS-RRSELKRFYTIDTGQKK-TLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAVVTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTN-PDV-HPTEATPSSTFTG-IRPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIMFDPHKNDPLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPIDIDQLSGR-DFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSD--ELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKE-DQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALLKEKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFIQWSPEIYAEDTGEYTREPGFIVVKKIEESETIED--SSNQAAAREWEVVSVAEYHRRIDALNTEELRTLCRRLQITTREDINSKQVATVKADLESESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGTSLKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEFEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQDIEIWAFE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I3ISS4-1", "uniprot_id": "OXR1B_DANRE", "id": "I3ISS4-1", "name": "Oxidation resistance protein 1B", "aln": "---MFSTKRLKKKSQSVDIPDEGYAGSLVKDLLASPLIKN--VARTTIREEKEINTTNIQKARSPRRGELKRGYTIDTGQKKSALERKDVRRISFQRPKGTMEYVVESRDTLNSIALKFDTTPNELVQLNKLFSRAVVPGKVLYVPDPEYISSAESSPSLSPISPLSPTSSEADLEKATKGLDHVHRRHSSSTGLAHGPPRPARVVSSTSEEEEALTEKFLKMNCKYITDGKGIVSGVLLVTPNNIMFDPHKSDRLVQERGCEEYGIMCPLEEVQSAAMCREITDVRLREFVPPDLELEPSVSEVSHLKRAPRLNAADAAHRIRETGNDSASTAPRSTEASLSEDVFTESELSPVRDDALATSSDELQQIKSSGASSESVQTINQAATVTEDQSS--------------AGGTDVKEAGQIEGVGWRDSGIEQSLNTTDVFNEES-----CENVLENVQRDQSGDEP---KSRTTSESLCSDTVAVEDAVKETQKSLEDQSLQASSDVKEGELR------------TDSDSTAAVEPG-AEEGLKSAEEVVPG---LRGKQKSKLHKFLCLRVGRAMRKTFVSHASASMQQYAQRDRKHEYWFAVPSERSDHLFGFFVQWTPDVYGEGFGGLTREPGFVVVKKNQDAESGEQDKPVPDITFKDWEVVSVAEYYRRIDALNSEDLRSLCKRLQITTKEEVNSK--LMVKSDPEPETFRPNLTEPSVLLQPEHIEKLAKHLPPRTIGYPWSLAFSTSKHGMSMKSLYRAMQSQDSPVLMVIKDSDGQMFGALASQPFKVSDGFYGTGETFVFTFYPEFEVFKWTGDNMFFIKGDMDSLAVGGGGGEFGLWLDGDLYHGRTHSCKTFGNPMLSKTEDFFVQDIEIWAFE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ********** *: .* :* .: ..:*.* **:: *::* ** * *:.**** ********* :*::** **:***:****:**.*****:***************************.*:*********:**.********:**********:::*:*. * * .:..:. * ***************:******:****** *** ******************.* ****.**********:*** **** :** * :::* :* ::: .. .* *: . .: : * *: ************* *****.********:*:: ::: * :* ***.********:.* . : .* .: : .:. : . : : :: :: * . .: : ::*. .* :. :.: .. .. . . *. :.:. : .*:.: *** : :. *. ::. :*: . *: *:: :**********:.*******:***:********:*********.**:***:.**:**:*::*.*. * ******:**** :::*: * . : : ::*********:*******:*:**:**:******:*::*** .*:* *.*:*****::** ** *::****:************:*.:.*.*** *:*:***:* . *:************:******:*:***************** ************************.*******.***********:******** ***.****:*********", "identical_positions": 487, "similar_positions": 193, "identity": "54.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2449", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UHC7-1", "uniprot_id": "DAB2P_MOUSE", "id": "Q3UHC7-1", "name": "Disabled homolog 2-interacting protein", "aln": "----------------------------------------------------MSAGGNARKSTGRPSYYYRLLRRPRLQRQRSRSRSRTRPA--RESPQERPGSRRSLPGSMSEKNP-SMEP---SASTPFRVTGFLSRRLKGSIKRTKSQPKLDRNHSFR-------HILPGFRSAAAAAADNERSHLMPR-----------------------LKESRSHESLLSPSSAVEALDLSMEEEVIIKPVHSSILGQDYCFEVT-TSSGSKCFSCRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTSKLKTDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPVVTPNP-------KGGKGPG-------PMIRIKARYQTVSILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCS---SADLPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGRPDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTARTLTLIAKVTQNLANFAKFGSKEEYMSFMNQFLEHEWTNMQRFLLEISN---PETLSNTAGFEGYIDLGRELSSLHSLLWEAVSQLDQSVVSKLGPLPRILRDVHTALSTPGSGQLPG--------------TNDLASTPGSGSSSVSAGLQKMVIENDLSGLIDFTRLPSPTPENKDLFFVTRSSG-----------------VQPSPARSSSYSEANEPDLQMANGSKSLSMVDLQDARTLDGEAGSPVGPDALPADG---QVPATQLLAGWPARAAPVSLAGLATVRRAVPTPTTPGTSEGAPGRP-----------------------------------------------------------------------------------------QLLAPLSFQNPVYQMAAGLPLSPRG--LGDSGS---------------------EGHSSLSSHSNSEELAAAAK---LGSFSTAAEELARRPGELARRQMSLTE--KGGQPTVPRQNSAGPQRRIDQPPPPPPPPPPAPRGRTPPTLLSTLQYPRPSSG----------------------------------------------------TLASASPDWAGPGTRLRQQSSSSKGDSPELKPRAMHKQGPSPVSPNALDRT-------------------------AAWLLTMNAQLLEDEGLGPDPPHRDRLRSKEELSQAEKDLAVLQDKLRISTKKLEEYETLFKCQE-----------------------------------------------ETTQKLVLEYQARLEEGEERLRRQQE-------------------DKDIQMKGIISRLMSVEEELKKDHAEMQAAVDSKQKIIDAQEKRIASLDAANARLMSALTQLKERYSMQARNGVSPTNPTKLQITENGEFRNSSNC---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P730-1", "uniprot_id": "DAB2P_RAT", "id": "Q6P730-1", "name": "Disabled homolog 2-interacting protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPVVTPNP-------KGGKGPG-------PMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCS---AADLPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGRPDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTARTLTLIAKVTQNLANFAKFGSKEEYMSFMNQFLEHEWTNMQRFLLEISN---PETLSNTAGFEGYIDLGRELSSLHSLLWEAVSQLDQSIVSKLGPLPRILRDVHTALSTPGSGQLPG--------------TNDLASTPGSGSSSVSAGLQKMVIENDLSGLIDFTRLPSPTPENKDLFFVTRSSG-----------------VQPSPARSSSYSEANEPDLQMANGSKSLSMVDLQDARTLDGEAGSPVGPEALPADG---QVPATQLVAGWPARAAPVSLAGLATVRRAVPTPTTPGTSEGAPGRP-----------------------------------------------------------------------------------------QLLAPLSFQNPVYQMAAGLPLSPRG--LGDSGS---------------------EGHSSLSSHSNSEELAAAAK---LGSFSTAAEELARRPGELARRQMSLTE--KGGQPTVPRQNSAGPQRRIDQPPPPPPPPPPAPRGRTPPTMLSTLQYPRPSSG----------------------------------------------------TLASASPDWAGPGTRLRQQSSSSKGDSPELKPRALHKQGPSPVSPNALDRT-------------------------AAWLLTMNAQLLEDEGLGPDPPHRDRLRSKEELSQAEKDLAVLQDKLRISTKKLEEYETLFKCQE-----------------------------------------------ETTQKLVLEYQARLEEGEERLRRQQE-------------------DKDVQMKGIISRLMSVEEELKKDHAEMQAAVDSKQKIIDAQEKRIASLDAANARLMSALTQLKERYSMRARNGVSPTNPTKLQITENGEFRNSSNC---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5VWQ8-1", "uniprot_id": "DAB2P_HUMAN", "id": "Q5VWQ8-1", "name": "Disabled homolog 2-interacting protein", "aln": "----------------------------------------------------MSAGGSARKSTGRSSYYYRLLRRPRLQRQRSRSRSRTRPA--RESPQERPGSRRSLPGSLSEKSP-SMEP---SAATPFRVTGFLSRRLKGSIKRTKSQPKLDRNHSFR-------HILPGFRSAAAAAADNERSHLMPR-----------------------LKESRSHESLLSPSSAVEALDLSMEEEVVIKPVHSSILGQDYCFEVT-TSSGSKCFSCRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPVVTPNP-------KGGKGPG-------PMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCS---AADLPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGRPDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTARTLTLIAKVTQNLANFAKFGSKEEYMSFMNQFLEHEWTNMQRFLLEISN---PETLSNTAGFEGYIDLGRELSSLHSLLWEAVSQLEQSIVSKLGPLPRILRDVHTALSTPGSGQLPG--------------TNDLASTPGSGSSSISAGLQKMVIENDLSGLIDFTRLPSPTPENKDLFFVTRSSG-----------------VQPSPARSSSYSEANEPDLQMANGGKSLSMVDLQDARTLDGEAGSPAGPDVLPTDG---QAAAAQLVAGWPARATPVNLAGLATVRRAGQTPTTPGTSEGAPGRP-----------------------------------------------------------------------------------------QLLAPLSFQNPVYQMAAGLPLSPRG--LGDSGS---------------------EGHSSLSSHSNSEELAAAAK---LGSFSTAAEELARRPGELARRQMSLTE--KGGQPTVPRQNSAGPQRRIDQPPPPPPPPPPAPRGRTPPNLLSTLQYPRPSSG----------------------------------------------------TLASASPDWVGPSTRLRQQSSSSKGDSPELKPRAVHKQGPSPVSPNALDRT-------------------------AAWLLTMNAQLLEDEGLGPDPPHRDRLRSKDELSQAEKDLAVLQDKLRISTKKLEEYETLFKCQE-----------------------------------------------ETTQKLVLEYQARLEEGEERLRRQQE-------------------DKDIQMKGIISRLMSVEEELKKDHAEMQAAVDSKQKIIDAQEKRIASLDAANARLMSALTQLKERYSMQARNGISPTNPTKLQITENGEFRNSSNC---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PF31-1", "uniprot_id": "A5PF31_DANRE", "id": "A5PF31-1", "name": "", "aln": "------------------------------------------------------MSGVTRKGSGRPGYYYRLLGRTRLQRQRSRSRSRSRVTNNKDSPPERTGRRRSIPGSAPDKVPPTMEPTAAAAATPFRVTGFLSRRLKGSIKRTKSQPKLDRNSSFR-------HILPGFR-----PVDNERSHLMPR-----------------------LKESRSHESLLSPTSAVEALDLSMEEEVLIKPVHSSILGQDYCFEVS-TSTGSKCFSCRSAAERDKWMENLRRAIHPNKDNSRRVENMLRLWIIEAKDLPAKKKYFCELCLDDSLYARTTCKMKTDNVFWGEHFEFNNLPAVQSITVHVYRDSDKKKKKDKNNYVGLVSIPVVTVTSRQLVEKWYPVSQPNP-------GKGKAAG-------PMVRIKARYQSMNILPMELYKEFAEYTTNNYMLLCSVLEPVISVKNKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGENEHLIFRENTLGTKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCS---SSDLPEHQSNLRMCCELAFCKIIESYRVFPRELKEVFASWRQECGNRGRPDISERLISASLFLRFLCPAIMSPSLFNLTQEYPDDRTARTLTLIAKVTQNLANFTKFGNKEEYMSFMNQFLEQEWTNMQRFLLEISN---PETISNTAGFEGYIDLGRELSTLHSLLAEVLSQMDQSAASKLGPLPRILRDVHGALTNPTNVQMSV--------------PSDRVPSPPVPGCSISTGIQKMAIDSDLPGPVDFTRLPSPTPENKDLFFVTRSSG-----------------LQGSPTRSSSYSEANEPELGLANGGKSLSMVDLQEAARALEPISIPAG---ITSEG---MGEG--AMVPWNARTPQGNIAGGPTLHRPVQSPTTPG-AEGAPGRPT----------------------------------------------------------------------------------------QLLAPLSFQNPVYQMAAGLPVSARGNASGDSGS---------------------ECHSSVSSHSNNEECLGGTKTTFLTQGASVGEEFARRSGDFSRRQLSLTDPQHGNQPTVPRQSSAGPQRRIDQPPPP---TQTAPRGRTPPNLLNSGPYPRPLNN----------------------------------------------------TMMSSSPDWPGSGARLRQQSSSSKGDSPETKHRAPHKQAPSPVNPSALDRT-------------------------AAWL--MNVPYIEQE---PETELCRDEHTQAEKYQAE--ISMLQDRLRMSVQRLEEYEARLKGQE-----------------------------------------------EQAQKMLLEYQARLDESEERLRRQQE-------------------DKDLQMKGIISRLMSVEEELKKDHADMQAVVDSKQKIIDAQEKRIASLDAANARLMSALSQLKERYSMQTRNGISPTNPTKLQITENGEFRNSSNC---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8T498-1", "uniprot_id": "GAP2_DROME", "id": "Q8T498-1", "name": "Ras GTPase-activating protein raskol", "aln": "MGRRTYLSRSSTISYPSRIEGWLDVCETEGELTRLIKTLPWGPLYCVLQQDDQTFTAYCSEEISLGDVCYEDIPRVRLDRVRRPAKALWDGPPTLVEENEDSDSCVGGSGGMSGINDIVLNTTLYSELGEYKSKTLPRIHFDTALNDTSLNEDTSYEKACRRGSAPTTPILGSKQHQTEHNATSRFTNFFSKKSNPLKRTKSVTKLERTKRGSGGLRGSRSHESLLSSHAVMSTIDLSCTGAVGVAPVHQSVLGRRHCFQVRGGPRGERYYSCGSRQERDLWIYSLRKSIAPNAEHTRRTDNSLKMWVYEAKNLPPKKRYFCELQLDKTLYGRTSVKLQTDLLFWGEHFDFPDIPEINVITVNVFREVDKKKKRDKYQFVGSVKIPVHDVTSRLPCEQWYPILSDKAGDSLGRTSGGGGSGSKDKEQLPTLRIKCRFQSTDILPINVYGNFLTYLKENYKRVCETLEPVIGVKAKEDIGQALVLLMHAQGLAGAFLTDVVALDLLRVGD-QRLTFRGNSLATKSMEAFLKLTGEQYLQDTLSAPINELIQSERDCEVDPTKTSGSSAGSLQRQQAALRGAVRGAWQCIFESHKHFPAQLRNCFATFRERLQQLGRQDMADNLISASIFLRFLCPAILSPSLFNITSELPSARATRNLTLVAKTLQTLANFTRFQGKENFMEFLNDFLEQEAARMQQFLEIISTRPEHPAPDSILDWAGYIDQGKQLSILHSLLSESLAKLPEARQHELDPLQHILDEISRAKEHGMGTALPGGYLPATSSTHSIASENQENRNPGSSGSHAGSNSEQLLPQQSQLAQPQHAIVSKPLSAERGIMRGVLTPNSLEKNIFRYNDPTVNGLLQQQQQQQQQQQQQQQQHQQLQQHGHQQQPHHQHPLQMLSNSQTSIAGNQYMSSPGGLQHAQSQTSMASSSLNGSSSNLLHGHQQHAHHPQQLHPHHCPPAPQTSASSTMERMDRMNYPYMSHNGNDYETSTPSSTRSRTLPRNGNPNANGNVGSSNNNQSGSYDDMHGEFQIQISGFDTSSAFVCKSPTPMMKSSLGPAGAGRSHHKLNLGIPDHSGGYVRGNNLNPNSNMPKNLEDLDDLFKYAEEHDVAEPANHHNHNQGQQNHQGHLKPAAVPGKEQLSAKSSHCSSGYQSISTNPSPSQSSSPVESQLKAAMGSHNAPLAFKNPSYQLQPQTGSSRSSAQSNTHQQQQQQQQQQFGSRLKPIGGGLVAARAAFLNSGGALEAATLTPSSSDEQLSADNYFSYAAAAAAGAGIATKLEAQRSLSGGSSSSTSASASTSNLGKSGGSSAYGRLNGPLKREDVYGSGYGGSSGNVGYGLSTSSAAGHHQHPHQQQQNPMQQQQQRERDQEHKQYAGSVAGSVGSATSAAQRRLSLDSARTLSDSSTDTEGHCNQLQEGKRRRQLRSSGGSGGGGAGSEQGLGKSYDQNGEIQLLQQTLDTLCHTLDRDEAELRDSSDELFGLQRPAGSNGSNNLSLQSESTMRSIIDRLITMEEELRREQLKMSLALSHKQRVIEEQGQQIAALDAANSRLLSALTALRQRYETQQQQQQHQAPPKTQKPQ--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33314-1", "uniprot_id": "BUD2_YEAST", "id": "P33314-1", "name": "Inhibitory regulator protein BUD2/CLA2", "aln": "-----------------------------------------------------------------------------MSSNNEPAQSRTSYFKLNEFLSNVKHYKNTFKGEIQWCNNLSLNDWKTHYLQITSTGALTHSIDELTADSTNIQPIIKHLQQCR------------------------------------------------------------IEIIKDKHSSFKDINANCN---FIIQVNTSGKDNKVYLRVKSWSDFKKLLTC------LIWWSSMKTNGIFNKFQVSRPLEFKSKKMAKPESLLVYKLNVFGPIVKNIVLPPATNILESPDIINNDDNSVGWFSAMGVLKSNGMLDLLLQSDGSLIYSLNISQLLRSEIR----------ILDSS--------------------------VLQSENSLFLGELPLLRSQLGLEKFRIENIASAATNSSDISQEIIVEFPLRIDLEDCFIALQSFARSEYLSITGSDKSNDMKIS-NSFKISILEANFQSINLNDKNNTPWSIFTDITAWGHTWARTSMVSN----SSNPFWREEFQFNELLRLTNSYLEIKQLFHDLNN-----KKRLRLIGKIKITQEIINDTRYNKETRLPIMDVDNKNFQIGTICIKISSNLNFILPSTN-FVKLEKLLMNAN-LSMVSNLIYKSSSSMENDNKLTQT--------SIIFLDIFQSLSRIEEWFHVLIDKELAKIDG-TVSRINQKNLDSKHVFNSLFRGNSILTKS-------------IEQYFFRVGNEYLSKALSAILKEIIESNKSCELDPARVKEKDEVKKRKIIADNYKR-----------------LYSWVTKIWKRLYATSNDLPIEIRNVLKIFRQKLEIICIDDTLQIILNG---ISGLLFLRFFCPVILNPKLFKYVSQNLNETARRNLTLISKVLLNLSTLTQFAN-----------------------------------------------------------------------------------------KEPWLMKMNNFIDKRHNDLLDYIDKMTQKKLDFN--------------------SKILNLSSTISRPKLAIEQTMLDDLPQIPYLLDKNLRETEFVNLIVNFSQ---EDMTKMEKYNHMDNGGKGELIEEEGLLSGSSLNLSVDKKDLDSPIEVKPEIG-----------------------------------------------ELEFEKITENNTEIFGDDLMNLLKSDDVGSRSRDLDNGANSGIKFNSIIPKAEEEK--------------------------------HAMKELEQESCLLYNRINHIRKRLSGYECASSTLFEDKKYSISLSHKIFYEEIKEGKE------------------------------------------------IVLKLLNKPTNENSSARLQKFFTKG----------------VSSKSNNTVGDSYCKFLTIDVSDENPKSSNKTSVHGTSSENGAKDDYLTLPNSQGKGNLGNRFSPTKLSRIMRKPPNADVPKEQNSRKLTRWFKKKKETGGS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: * : * . : :.:.* * . :.. : :: ::: :: .:. .. :. : :. : : :.. . :. .: : : . : :: : : : . . . :. . . . : : .* :. . :: .: .. : : : *:: . :* :: . : ::: :. : . . . .. : :: . : :*.: ::. *: .:::.:*. : : : .*:. . *: : : .*.:: : :.:: :: : : :.::.::: :. : *:. .. . : . .: . :* *: : :::: .:. .: : . . . : : :.. : : : . :: : : : . . . : . . . : : . .: . . : . . : .: . . :. . : . : : . .:: . .. . . . . . . .: : . . * : . . * . . * .. ..* . : :: : : . . : : . .. : : . . . . ..: : . :::::: . .. : . . : .. : . :: :: . :. : : . . ", "identical_positions": 20, "similar_positions": 294, "identity": "1.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2453", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q01320-1", "uniprot_id": "TOP2A_MOUSE", "id": "Q01320-1", "name": "DNA topoisomerase 2-alpha", "aln": "--MELSPLQPVNENMLMNK-KKNEDGKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQMWVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNVISIWNNGKGIPVVEHKVEKIYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQTWMDNMGRAGDMELKPFSGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNSLPVKGFRSYVDLYLKDKVDETGNSLKVIHEQVNPRWEVCLTMSERGFQQISFVNSIATSKGGRHVDYVADQIVSKLVDVVKKKNKGGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQIQLNKKCSAVKHTKIKGIPKLDDANDAGSRNSTECTLILTEGDSAKTLAVSGLGVVGRDKYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEIAFYSLPEFEEWKSSTPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQVDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQSTSYLTYNDFINKELILFSNSDNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLRFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLLDGEEPLPMLPSYKNFKGTIEELASNQYVINGEVAILDSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPSLITDYREYHTDTTVKFVIKMTEEKLAEAERVGLHKVFKLQSSLTCNSMVLFDHVGCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESSKLNNQARFILEKIDGKIVIENKPKKELIKVLIQRGYDSDPVKAWKEAQQKVPDEEENEESD--TETSTSDSAAEAGPTFNYLLDMPLWYLTKEKKDELCKQRNEKEQELNTLKQKSPSDLWKEDLAVFIEELEVVEAKEKQDEQVGLPGKAGKAKGKKAQMCADVLPSPRGKRVIPQVTVEMKAEAEKKIRKKIKSE----------NVEGTPAEDGAEP---GSLRQRIEKKQKKEPG--AKKQTTLPFKPVKKGRKKNPWS--DSESDVSSNESNVDVPPRQKEQRSAAAKAKFTVDLDSDEDFSGLDEKD--------EDEDFLPLDATPPKAKIP----PKNTKKALKTQGSSMSVVDLESDVKDSVPAS--PGVPAADFPAETEQSKPS-KKTVGVKKTATKSQSSVSTAGTKKRAAPKG---TKSDSALS--ARVSEKPAPAKAKNSRKRK-----PSSSDSSDSD----FERAISKGATSKKAKGEEQDFPVDLED------TIAPRAKSDRARKPIKYLEESDDDDDLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11388-1", "uniprot_id": "TOP2A_HUMAN", "id": "P11388-1", "name": "DNA topoisomerase 2-alpha", "aln": "--MEVSPLQPVNENMQVNKIKKNEDAKKRLSVERIYQKKTQLEHILLRPDTYIGSVELVTQQMWVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQTWMDNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKLDETGNSLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTLQPKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQVQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDKYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKSSTPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPLPMLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGTEKTPPLITDYREYHTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQRGYDSDPVKAWKEAQQKVPDEEENEESDNEKETEKSDSVTDSGPTFNYLLDMPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKEDLATFIEELEAVEAKEKQDEQVGLPGKGGKAKGKKTQM-AEVLPSPRGQRVIPRITIEMKAEAEKKNKKKIKNE----------NTEGSPQEDGVEL---EGLKQRLEKKQKREPGTKTKKQTTLAFKPIKKGKKRNPWS--DSESDRSSDESNFDVPPRETEPRRAATKTKFTMDLDSDEDFSDFDEKT--------DDEDFVPSDASPPKTKTS----PKLSNKELKPQKSVVSDLEAD-DVKGSVPLS--SSPPATHFPDETEITNPVPKKNVTVKKTAAKSQSSTSTTGAKKRAAPKG---TKRDPALN--SGVSQKPDPAKTKNRRKRK-----PSTSDDSDSN----FEKIVSKAVTSKKSKGESDDFHMDFDS------AVAPRAKSVRAKKPIKYLEESDEDD-LF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IUF0-1", "uniprot_id": "A0A0R4IUF0_DANRE", "id": "A0A0R4IUF0-1", "name": "DNA topoisomerase 2", "aln": "MAGTEGPLKSLFENKALSKPKKDE---KRLSVERIYQKKTQLEHILLRPDTYIGSVEPVTQQMWVFDEDTGMNCRDITFVPGLYKIFDEILVNAADNKQRDKTMNCIKVNIDPENNTISVWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSLKFTVETACRESKRCFKQTWFDNMGRAGESKIKPFDGDDYTCITFQPDLAKFKMQALDKDTVALLTRRAYDIAGSTKGVRVLLNGKRLPINNFRTYVDLYVKDKVDETGSPLTVVHEMVNERWEVCLTLSEKGFQQVSFVNSIATTKGGRHTDYVADQIVSKLIEVVKKKNKAGVAVKPFQVKNHMWLFVNCLIENPSFDSQTKENMTLQQKNFGSACSLSDKFVKQANGCGIVESIMNWVKFKAQAQLNKKCSAVKHTKIKGVPKLDDANDAGGKNSNSCTLILTEGDSAKTLAVSGLGVVGRDRYGVFPLRGKMLNVREASHKQIMENAEINNIIKILGLQYKKNYSDPESLKSLRYGKLMIMTDQDQDGSHIKGLLINFIHHNWPSLLRHNFLEEFITPIIKASNKKQEISFYSIPEFTEWKEKQSSIKSWKIKYYKGLGTSTSKEAKEYFSDMTRHRIPFKYSGPADDEAITLAFSKKMIEERKEWLTSFMINRRQRREHNLPEEYLYGQETKSLSYHDFINKELVLFSNSDNERSIPCMVDGLKPGQRKVVFCCFKRNDKREVKVAQLAGSVAEMSAYHHGEVSLMMTIVGLAQNFVGSNNLNLLQPLGQFGTRLHGGKDSASPRYIFTMLSTLARLLFPVVDDNLLKYNYDDNLRVEPEWYMPIIPLVLANGGEGIGTGWASRIPNYDVREIINNIHRMLNGEEPLPMLPSYKGFKGTIDELAKNQYVNNGEVAIIDSTTIEITELPVKTWTQTYKENVLEVMLNGTEKVPALITDYKEYHTDTTVRFVVKMTEERLREAEAAGLHKVFKLQNLLTCNSMVLFDHVGSLKKYESVQDILKEFFELRMKYYVLRKDWLVGMLGAESAKLSNQARFILEKIQGTLVIENKPKKELIRMLQQMGYDSDPVKAWKDAQEKE--EEEDAEDD--DEKEKED---TSGPDYNYLLSMPMWYLTKEKKDELCKQRDAKMTELNTLKMKAPADLWKEDLAAFTEELERVEQKEKESQNAMPLVKGKVGKPKVVKVKNETMPTPQGRRVIPRITSTMKVQAVKKERGKGSKKEAGLVMKMEFDDEADAAADGTGVGLAARLTKKIKKEPTKDKGSKSGKQTTLTFKPVQK---KNPWSSDEGESDSDLELMSEETAPREKRERRAAVEKKYSLSS-SEDEFDDFTKSSKTKRAVIEDDESFNPEPSAAPDSDVDSPPPPVVKKAPTKVAKAKAEKPEASSKSSSHSEASQEPAPKPVKKTAEGAAKKPPAKMTSAVSKKKAADSKQPSILDVLSKASPKKSKVVKKPTAVKPLSSDSDSAGPAVTKKQAKKRKTVLSSDQSDSSDSDSGNLMSRLKGKSTAGKKAKSWEDDESFQLEETEKVVVSAAPRSRAARTTKPVTYALDSDSDDED-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .**:.: ** :.* **:* ****:************************* *******:***.*:* *::************************ .*.**:*.****** **:****************:*************************************** *******.** *: *****:*******: ::***.*:***********:*****:**** ***:.***********.*:*:***: **::.**:***:*:***:****..*.*:** ** *******:**:****:********:*****.********:**::*******.*****..*******:***.*****:************ *.***:*.**:**:* * ********:******** ***********.:***:**********.:**..*************************:*********:***********************:********.* :***:*****:*******************************.*********:*.*::***::***:*** ***.. .. *.**:******************:**.**** ****** ** **:****** :::******.** :****: .***:***** *. *:*:*******:************.************:* ***********************:*****:******:.****************:************************.******* **: *:: **** *******:****:** **.*******:.:***:****::***:*:::************.*****:*** **** .*****::******:***::********:*** *******.*.*****:********:**:*****:* *** .*********. *************.****::* ***::*****:*** ***:**:*******:**.**********:*.::**********::* * ***********:**:* ***: *.* *....* :** :****.**:************: *: * **:*** *:*:********.* **** ** ***:.::. *. .* * .:: :.:*:*:*:****::* **.:* ** : * ..: : *. . **. * ::::*: .:: * : *****.***::* :**** :.*** . : . :..**:.. * **.: *:::. *:::*..: :. :**.* * ::.*.:. * .: * : . : . . .. * .. ... . * .:* * . *.*. : .... * .. .:*:** .* .*:. : *:.. ** :*: *:: .. **.***: :.: .*..:.**:*. .:* .:::. : ***::: *: **:.* :**.** ", "identical_positions": 1018, "similar_positions": 330, "identity": "64.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2457", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CIA5-1", "uniprot_id": "S35B4_MOUSE", "id": "Q8CIA5-1", "name": "Nucleotide sugar transporter SLC35B4", "aln": "----MRPAFAVGLVFAGCCSNVIFLELLARTHPG-CGNIVTFAQFLFIAVEGFLFEANLGR-----KPPAIPIRYYAIMVTMFFTVSVVNNYALNLNIAMPLHMIFRSGSLIANMILGIIILKKRYSMFKYTSIALVSAGIFICTFMSAKQVTVQTGLS---DKDGFQAF-AWWLLGIAALTFALLMSARMGIFQETLYRQFGKHSKEALFYNHALPLPGFIFLASDIYDHVVLFNKSELYQVPVIGVT-----MPVMWFYLLMNVVTQYVCIRGVFILTTECTSLTVTLVVTLRKFVSLIFSILYFQNQFTMWHWLGTSFVFIGTLMYTEVWKNLGTTKSELQKDDKKD----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZAN4-1", "uniprot_id": "D3ZAN4_RAT", "id": "D3ZAN4-1", "name": "Solute carrier family 35 member B4", "aln": "----MRPAFAVGLVFAGCCSNVIFLELLARTHPG-CGNIVTFAQFLFIAVEGFLFEADLGR-----KPPAIPIRYYAIMVTMFFTVSVVNNYALNLNIAMPLHMIFRSGSLIANMILGIIILKKRYSMFKYTSIALVSAGIFICTFMSAKQVTVQSSLS---DKDGFQAF-AWWLLGIGALTFALLMSARMGIFQETLYRQFGKHSKEALFYNHALPLPGFIFLASDIYDHVVLFNKSELYQVPVLGVT-----VPIMWFYLLMNVVTQYVCIRGVFILTTECSSLTVTLVVTLRKFVSLIFSILYFQNQFTLWHWLGTVFVFTGTLMYTEVWKNLGATKSQLQKDDKKD----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q969S0-1", "uniprot_id": "S35B4_HUMAN", "id": "Q969S0-1", "name": "Nucleotide sugar transporter SLC35B4", "aln": "----MRPALAVGLVFAGCCSNVIFLELLARKHPG-CGNIVTFAQFLFIAVEGFLFEADLGR-----KPPAIPIRYYAIMVTMFFTVSVVNNYALNLNIAMPLHMIFRSGSLIANMILGIIILKKRYSIFKYTSIALVSVGIFICTFMSAKQVTSQSSLS---ENDGFQAF-VWWLLGIGALTFALLMSARMGIFQETLYKRFGKHSKEALFYNHALPLPGFVFLASDIYDHAVLFNKSELYEIPVIGVT-----LPIMWFYLLMNIITQYVCIRGVFILTTECASLTVTLVVTLRKFVSLIFSILYFQNPFTLWHWLGTLFVFIGTLMYTEVWNNLGTTKSEPQKDSKKN----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZW46-1", "uniprot_id": "S35B4_DANRE", "id": "Q7ZW46-1", "name": "UDP-xylose and UDP-N-acetylglucosamine transporter", "aln": "----MNTLFAVTLVFVGCCSNVVFLELLVRDFPG-CGNIVTFAQFAFIALEGFIFETNFGR-----KKPQIPLSNYVIMVTMFFTVSVINNYALDFNIAMPLHMIFRSGSLIANMILGIIILKNRYSMSKYLSIVLVSVGIFICTIMSAKQVNVEKGGT---EEDGVYAF-MHWLLGIAMLTFALLMSARMGIFQETLYKKYGKHSKEALFYNHCLPLPGFLLLSTNIYNHAVLFSQSPPMEVPVIGLS-----MPVMWFYLLMNVITQYVCIRGVFILTTECASLTVTLVVTLRKFLSLIISILYFQNPFTAWHWVGTAVVFLGTLLYTEVLSSIPAAFKGYKVDKKAE----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W429-1", "uniprot_id": "S35B4_DROME", "id": "Q9W429-1", "name": "Endoplasmic reticulum GDP-fucose transporter", "aln": "MALNLKALLGMLFVFIGCCSNVVFLELIIQIDPG-AGNLITFAQFLFIALEGLVFTSKFFT-----VRPKIALKDYVILVALFFGANVCNNYAFNFNIPMPLHMIFRSGSLMANMIMGIVLLKKRYNLRQYSSVAMITAGIILCTLVSSGDVKDNTHHSLKVDT-SYSDF-FWWTVGIGLLTIALLVTAYMGIYQEVIYKKYGKHPSEALFFTHMLPLPGFLIMAGNIVQHFGIAWSSEPVAVPLLGAIGLEWKFPLMLFYLLCNVVTQYVCISAVYVLTTECASLTVTLVVTLRKFVSLLFSIIYFRNPFTLNHWVGTILVFFGTILFANVINQVRDAYRARSSRKTHFDTAPLAKKVE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAN9-1", "uniprot_id": "Q9VAN9_DROME", "id": "Q9VAN9-1", "name": "UDP-xylose and UDP-N-acetylglucosamine transporter", "aln": "MNLSIRAISAICGVFLGCCSGVVFLELLVKLDPG-AGNLITGAQFAFIALEGFIFTSKFGL-----AQRVISLRDYALLVAMFFLTSVCNNYVFKFKVPMTLHMIIRGGSLISNMCLCTLILKRSYRLSQYISVLMISVGIFVCTYFSSPDLVGKMEN---LDSGAEADT-FWWLLGVALLVLALFVSSYMGITQELLYRRHGKCAREALYYTHLLPLPAFLLMHDDIRTHWLLAFTGESYQLPLLGVA-----VPLILLYLLGNVLAQHLCISSVYTLTTECSSLTVTLILTLRKFISLVFSIVYFRNPFTWWHWLGTALVFVGTLMFANVIRVPK-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40004-1", "uniprot_id": "YEA4_YEAST", "id": "P40004-1", "name": "UDP-N-acetylglucosamine transporter YEA4", "aln": "---MWNSLKAFALVFGGCCSNVITFETLMSNETGSINNLITFCQFLFVTCQGLPEFLDVHQPFPYFKPLKTPLHVYVITVVLFYISSTTNNNVFKYNISIPIHIVFRCFGTVITMFTCWLLNGRKYTKIQILSTLFLTIGAIIASLFKDADFRYQDLKLQAWKIGSDQSVDLTFIFGICILVLSSFTSSLLSAYNERTYQKYGKHWKENIFYSHFLSLPLFLFSRKQLIHEYRVMRKSERILCSNFGGK---ILVPREETLLLFNVLTQYFCVKGVNILASKTNALTLSITLLVRKFISLLLSVRLFDNNLSYTGYIGVYLVFFGAFIYSLGSIHPRQNDKGAIKKSK------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .. ** ****.*: :* : .* .*::* .** *:: :*: .. .: *.: *.:*: .. ** .:. ::.:.:*:::* . : .* :: . * : * ::: * ::.: .. :. : . . : .*: *.:: : :: :. :* *::.** * :::.* *.** *:: :: . : . . :* .* ** *:::*:.*: .* *::: :**::: : :***:**::*: * * :: ::*. .** *::::: ", "identical_positions": 61, "similar_positions": 122, "identity": "16.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2458", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P58366-1", "uniprot_id": "ANKH_RAT", "id": "P58366-1", "name": "Mineralization regulator ANKH", "aln": "MVKFPALTHYWPLIRFLVPLGITNIAIDFGEQALNRGIAAVKEDAVEMLASYGLAYSLMKFFAGPMSDFKNVGLVFVNSKRDRAKAVLCMVVAGAIAAVFHTLIAYSDLGYYIINKLHHVDESVGSKTRRAFLYLAAFPFMDAMAWTHAGILLKHKYSFLVGCASISDVIAQVVFVAILLHSHLECREPLLIPILSLYMGALVRCTTLCLGYYRNIHDIIPDRSGPELGGDATIRKMLSFWWPLALILATQRISRPIVNLFVSRDLGGSSAATEAVAILTATYPVGHMPYGWLTEIRAVYPAFDKNNPSNKLANTNNTVTSAHIKKFTFVCMALSLTLCFVMFWTPNVSEKILIDIIGVDFAFAELCVIPLRIFSFFPVPVTVRAHLTGWLMTLKKTFVLAPSSVLRIIVLITSLVVLPYLGVHGATLGVGSLLAGFVGESTMVALAACYVYRKQKKKMENES--ATEGEDSA-MTDMPPAEEVTDIVEMREENE------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHZ2-1", "uniprot_id": "ANKH_MOUSE", "id": "Q9JHZ2-1", "name": "Mineralization regulator ANKH", "aln": "MVKFPALTHYWPLIRFLVPLGITNIAIDFGEQALNRGIAAVKEDAVEMLASYGLAYSLMKFFTGPMSDFKNVGLVFVNSKRDRAKAVLCMVVAGAIAAVFHTLIAYSDLGYYIINKLHHVDESVGSKTRRAFLYLAAFPFMDAMAWTHAGILLKHKYSFLVGCASISDVIAQVVFVAILLHSHLECREPLLIPILSLYMGALVRCTTLCLGYYRNIHDIIPDRSGPELGGDATIRKMLSFWWPLALILATQRISRPIVNLFVSRDLGGSSAATEAVAILTATYPVGHMPYGWLTEIRAVYPAFDKNNPSNKLANTSNTVTSAHIKKFTFVCMALSLTLCFVMFWTPNVSEKILIDIIGVDFAFAELCVIPLRIFSFFPVPVTVRAHLTGWLMTLKKTFVLAPSSVLRIIVLITSLVVLPYLGVHGATLGVGSLLAGFVGESTMVALAACYVYRKQKKKMENES--ATEGEDSA-MTDMPPTEEVTDIVEMREENE------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCJ1-1", "uniprot_id": "ANKH_HUMAN", "id": "Q9HCJ1-1", "name": "Mineralization regulator ANKH", "aln": "MVKFPALTHYWPLIRFLVPLGITNIAIDFGEQALNRGIAAVKEDAVEMLASYGLAYSLMKFFTGPMSDFKNVGLVFVNSKRDRTKAVLCMVVAGAIAAVFHTLIAYSDLGYYIINKLHHVDESVGSKTRRAFLYLAAFPFMDAMAWTHAGILLKHKYSFLVGCASISDVIAQVVFVAILLHSHLECREPLLIPILSLYMGALVRCTTLCLGYYKNIHDIIPDRSGPELGGDATIRKMLSFWWPLALILATQRISRPIVNLFVSRDLGGSSAATEAVAILTATYPVGHMPYGWLTEIRAVYPAFDKNNPSNKLVSTSNTVTAAHIKKFTFVCMALSLTLCFVMFWTPNVSEKILIDIIGVDFAFAELCVVPLRIFSFFPVPVTVRAHLTGWLMTLKKTFVLAPSSVLRIIVLIASLVVLPYLGVHGATLGVGSLLAGFVGESTMVAIAACYVYRKQKKKMENES--ATEGEDSA-MTDMPPTEEVTDIVEMREENE------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P58368-1", "uniprot_id": "ANKHB_DANRE", "id": "P58368-1", "name": "Progressive ankylosis protein homolog B", "aln": "MMKFPALTHYWPLIRFLVPLAITNIAIDLGEQALNRGIAAVKEDAVEMLASYGLAYSLMKFFTGPMSDFKNVGLVFVNSKRDRTKAVLCMVVAGTVAIVFHTLIAYTNLGYYIINKLHHVDESVGSKTRKAFLYLAAFPLLDAMAWTHAGILLKHKHSLLVGCASISDVVAQIVFVGILLHSHLECVEPMLIPILSLYMGALVRFTIVGLGYYKVIHDNIPESSGPEVGGDATIKKMLSFWWPLALILATQRISRPIVNLFVSRDLKGSTAATEAVAVLTATYPVGHMPYGWLTELRAVYPAFDKNNPSNKLINSGTVVTKSHIKRFTFFCLALSITLCFMVFWAPHISESILVDIIGVDHAFAELCITPLRIFSFFPIPVTIRAHLTGWLMTLKKTFVLAPSSVLRIIVLISSLIVLPYMGVHGATLGVGSLLAGFLGESTMVAIAACYVYRKQKKKKDSDEDMTIDGEDSAPMNEVRSRGRMDDIVELREEDEEELDED", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:******************.*******:*********************************:********************:**********::* ********::*********************:*********::***************:*:**********:**:***.********* **:************** * : ****: *** **: ****:******:******************************* **:*******:*****************:**************** .:...** :***:***.*:***:****::**:*::**.**:******.******: *********:***:*****************************:**:****:****************:*******:************ :.:. : :***** *.:: . .: ****:***:* ", "identical_positions": 408, "similar_positions": 66, "identity": "81.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2459", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AXX6-1", "uniprot_id": "PXL2A_RAT", "id": "Q6AXX6-1", "name": "Peroxiredoxin-like 2A", "aln": "MSFLQDSSFFSMGMWSIGVGAFGAAALALLLANTDMFLSKPQKAALEYLEDIDLKTLEKEPRTFKAKELWEKNGAVIMAVRRPGCFLCRAEAADLMSLKPKLDELGVPLYAVVKEKVKREVEDFQPYFKGEIFLDEKKKFYGPERRKMMLMGLVRLGVWYNSFRAWKGGFSGNFEGEGFILGGVFVIGSGKQGVLLEHREKEFGDRVNLLSVLEAVKKIKPQTPASRQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CYH2-1", "uniprot_id": "PXL2A_MOUSE", "id": "Q9CYH2-1", "name": "Peroxiredoxin-like 2A", "aln": "-----------MGMWSIGVGAVGAAAVALLLANTDMFLSKPRKAALEYLEDIDLKTLEKEPRTFKAKELWEKNGAVIMAVRRPGCFLCRAEAADLMSLKPKLDELGVPLYAVVKEQVKREVEDFQPYFKGEIFLDEKKKFYGPERRKMMFMGLIRLGVWYNSFRAWNGGFSGNLEGEGFILGGVFVIGSGKQGILLEHREKEFGDRVNPLSVLEAVKKIKLQTPASGRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BRX8-1", "uniprot_id": "PXL2A_HUMAN", "id": "Q9BRX8-1", "name": "Peroxiredoxin-like 2A", "aln": "MSFLQDPSFFTMGMWSIGAGALGAAALALLLANTDVFLSKPQKAALEYLEDIDLKTLEKEPRTFKAKELWEKNGAVIMAVRRPGCFLCREEAADLSSLKSMLDQLGVPLYAVVKEHIRTEVKDFQPYFKGEIFLDEKKKFYGPQRRKMMFMGFIRLGVWYNFFRAWNGGFSGNLEGEGFILGGVFVVGSGKQGILLEHREKEFGDKVNLLSVLEAAKMIKPQTLASEKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PBP3-1", "uniprot_id": "PXL2A_DANRE", "id": "Q6PBP3-1", "name": "Peroxiredoxin-like 2A", "aln": "-----------MGMWSLGLGAVGAAIAGLILANTDFLLTKSAPATVDYLANADLKTIDGDERSLKAKALWEKSGAVIMAVRRPGUFLCREEASELSSLKPQLDELGVPLYAVVKENVGTEIQDFRPHFAGEIFLDEKQAFYGPQQRKMGGLGFIRLGVWQNFVRAWRAGYQGNMNGEGFILGGVFVMGSGGQGVLLEHREKEFGDKVSLESVLEAAKKVVVEK------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****:* **.*** .*:*****.:*:*. *:::** : ****:: : *::*** ****.*********** **** **::* ***. **:***********:: *::**:*:* ********: ****::*** :*::***** * .***..*:.**::***********:*** **:***********:*. *****.* : :. ", "identical_positions": 135, "similar_positions": 49, "identity": "58.95%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-246", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7F2H0-1", "uniprot_id": "F7F2H0_RAT", "id": "F7F2H0-1", "name": "Serine/threonine-protein kinase VRK3", "aln": "MRAQPLLSPPTPEVSAGQLKSMISFCPLCGKSVKVSFKFCPYCGEALP---VEEDGGT---QTGITPLVS---------------------PFRGSKRDLNSSSE---TSPKKVKWSRTVTSLPLSLHSDYDSSGSDDTLS-SPDRATGTRSRS---------------------QTPKGSPLANR---------------------LSPRTLKRSRVTTSLQALPTGTELTDQNGKHWTLGTLQTRDD-QGILYAAEPTSAISSESRTQKWRFSLKLDSK-------------DGRLFNEQNFFQRAAKPLQVNKWKKRCLTPLLAIPTCIG--------------------FGVHQDKYRFLVFPSLG-------------------RSLQSALDDNPKHVVSERCMLQVACRLLDALEYLHEHEYVHGNLTTENVFVNPEDLSQVTLVGYG-------FTYRYCPGGKHVAYKEGSRSLHDGDLEFISMDVHKGCGPSRRSDLQTLGYCMLKWLYG-----SLPWTNCLPNTEEITKQKQKYQDNPEPLVGLCGRWNKTSETLREYLKVVMALDYEEKPPYATLRNNLEVLLQNMRVSPYDPLDLQMVP----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K3G5-1", "uniprot_id": "VRK3_MOUSE", "id": "Q8K3G5-1", "name": "Serine/threonine-protein kinase VRK3", "aln": "---------------------MISFCPVCGKSVKVSFKFCPYCGKALP---VEEDGGT---QSAVTPHVS---------------------SVPGSRRDLNSSFE---TSPKKVKCSHTVTSLPLSRHSDCDSSGSDNTLT-SPDRATGTRSRP---------------------LTPKGSPLSNR---------------------QSPQTLKRTRVTTSLQALATGTELTDQNGKHWTLGALQIRDD-QGILYEAEPTSAVPSESRTQKWRFSLKLDSK-------------DGRLFNEQNFFQRVAKPLQVNKWKKQFLLPLLAIPTCIG--------------------FGIHQDKYRFLVFPSLG-------------------RSLQSALDDNPKHVVSERCVLQVACRLLDALEYLHENEYVHGNLTAENVFVNPEDLSQVTLVGYG-------FTYRYCPGGKHVAYKEGSRSPHDGDLEFISMDLHKGCGPSRRSDLQTLGYCMLKWLYG-----SLPWTNCLPNTEKITRQKQKYLDSPERLVGLCGRWNKASETLREYLKVVMALNYEEKPPYATLRNSLEALLQDMRVSPYDPLDLQMVP----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IV63-1", "uniprot_id": "VRK3_HUMAN", "id": "Q8IV63-1", "name": "Serine/threonine-protein kinase VRK3", "aln": "---------------------MISFCPDCGKSIQAAFKFCPYCGNSLP---VEEHVGS---QTFVNPHVS---------------------SFQGSKRGLNSSFE---TSPKKVKWSSTVTSPRLSLFSDGDSSESEDTLS-SSERSKGSGSRP---------------------PTPKSSPQKTRKSPQVTRGSPQKTSCSPQKTRQSPQTLKRSRVTTSLEALPTGTVLTDKSGRQWKLKSFQTRDN-QGILYEAAPTSTLTCDSGPQKQKFSLKLDAK-------------DGRLFNEQNFFQRAAKPLQVNKWKKLYSTPLLAIPTCMG--------------------FGVHQDKYRFLVLPSLG-------------------RSLQSALDVSPKHVLSERSVLQVACRLLDALEFLHENEYVHGNVTAENIFVDPEDQSQVTLAGYG-------FAFRYCPSGKHVAYVEGSRSPHEGDLEFISMDLHKGCGPSRRSDLQSLGYCMLKWLYG-----FLPWTNCLPNTEDIMKQKQKFVDKPGPFVGPCGHWIRPSETLQKYLKVVMALTYEEKPPYAMLRNNLEALLQDLRVSPYDPIGLPMVP----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N4J9-1", "uniprot_id": "A0A8M1N4J9_DANRE", "id": "A0A8M1N4J9-1", "name": "", "aln": "---------------------MLNFCPQCGSKLQAGFRFCPSCGEKLPENPTDEDEPSPQQESHINAVISSVSAMEVDCAGDSSPSALSRPPLRTTRRKTLSNTNTEYTEQKPVPSSRKRKSSQLVKEEEEVAKKTQSILSQTPDKTSFTPPRKGKASPQIKEQDEIKQTNLSTLQTPDKMSSMSLQKYKASPLIKDEEAKKTSPAIQSPSKCKSKKRVSSVDPVLEGTVVCDQSGKKWKLIELLWKTE-LDVTYGVCQAN---QHAESDECKYMLRLGAK-------------EGHLFNEQNFHLRAAKPDAVEKWGKLHKLDFLGIPSCVG--------------------FGLHET-YRFLVFPCMG-------------------QPLQTELDEG-TGSLSEKNVLQLALRLLDSLEFIHEKEYAHADIHAGNIYIKSSSHTEVFLSGFG-------HAFRFCPGGKHVEYRQGSRTAHQGNISFISLDSHKGAGPSRRSDLQSLGYCMLCWMTG-----SLPWSHLSHNSSSVAAEKERYMSDVPGLLTYCYKQKKASSALQEYLCNVMALQYTEKPDYTLLKGGLQQSLQKMGGSLK-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KRY6-1", "uniprot_id": "NHK1_DROME", "id": "Q7KRY6-1", "name": "Nucleosomal histone kinase 1", "aln": "-------------MPRVAKPKAAAPAKKVVSAKKAKSKLYKMPEKVKEGTVFTDLAKG---QWRIGPSIG----------VGGFGEIYAACKVGEKNYDAVVKCEPHGNGPLFVEMHFYLRNAKLEDIKQFMQKHGLKSLGMPYILANGSVEVNGEKHRFIVMPRYGSDLTKFLEQNGKRLPEGTVYRLAIQMLDVYQYMHSNG---YVHADLKAANILLGLEKGGAAQAYLVDFGLASHFVTGDFKPDPKKMHNGTIEYTSRDAHLGVPTRRADLEILGYNLIEWLGAELPWVTQKLLAVPPKVQKAKEAFMDNIGESLKTLFPKGVPPPIGDFMKYVSKLTHNQEPDYDKCRSWFSSALKQLKIPNNGDLDFKMKPQTSSNNNLSPPGTSKAATARKAKKIDSPVLNSSLDEKISASEDDEEEEEKSHRKKTAKKVTPSARNAKVSPLKRVADSSPPSQKRVKTEPKSTPRERATPKASPKPRSTPKASPKPQTPTAARLRTPNAKINFSPSISLRGRPGGKTVINDDLTPQPRSKKTYEFNFELDVSMDANVIVNVKRKKKADQDKATAVDSRTPSSRSALASSSKEEASPVTRVNLRKVNGHGDSSTPGRSPRTPAVTVRKYQG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :. :: : : : : . :. . .. . : . * . * .: . . * . :. : . . . . * . .:: . . * : : : : . . . : *.: . :*: :. :. : . .:*. :* . .. : * :* * . :: . * .: :: : : .*.* * . : :: .. . . * . : * .. . : : . * . :. .. *: .:.:. : * : . :. . : .: . . : ..: :. * : .:. : : : ", "identical_positions": 22, "similar_positions": 129, "identity": "3.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2466", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q923B1-1", "uniprot_id": "DBR1_MOUSE", "id": "Q923B1-1", "name": "Lariat debranching enzyme", "aln": "---MRVAVAGCCHGELDKIYETLALAERRGSGPVDLLLCCGDFQAVRNEADLRCMAVPPKYRHMQTFYRYYSGEKKAPVLTIFIGGNHEASNHLQELPYGGWVAPNIYYLGLAGVVKYRGVRIGGISGIFKSHDYRKGHFECPPYN----SSTIRSIYHVRNIEVYKLKQLKQPVHIFLSHDWPRNIYHYGNKKQLLKTKSFFRQEVENSTLGSPAASELLEHLQPAYWFSAHLHVKFAALMQH-------QATDKDQAGK-------------------------ETKFLALDKCLPHRDFLQVLEIEHDPSA-PEYLEYDVEWLTVLRATDDLINVTGGLWNMPEDNG--LHTRWDYSATEETMKEVMEKLNHDPKVPCNFTMTAACYDPS-----KPQTQVKLVHRINPQTTEFCAQLGITDINVMIQKAREEEHHQCG--EYEQQGDPGTEESEEDRSEYNTDTSALSS-INPDEIMLDEEEEEEEEEEEAVSAHSDMNTPSVEPAS---DQASDLSTS----FSDIRNLPSSMFVSSDDASRSPASGEGKC--GETVESGDEKDLAKFPLKRLSDEHEPEQRK----------KIKRRNQAIYAAVDDGDASAE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UK59-1", "uniprot_id": "DBR1_HUMAN", "id": "Q9UK59-1", "name": "Lariat debranching enzyme", "aln": "---MRVAVAGCCHGELDKIYETLALAERRGPGPVDLLLCCGDFQAVRNEADLRCMAVPPKYRHMQTFYRYYSGEKKAPVLTLFIGGNHEASNHLQELPYGGWVAPNIYYLGLAGVVKYRGVRIGGISGIFKSHDYRKGHFECPPYN----SSTIRSIYHVRNIEVYKLKQLKQPIDIFLSHDWPRSIYHYGNKKQLLKTKSFFRQEVENNTLGSPAASELLEHLKPTYWFSAHLHVKFAALMQH-------QAKDKGQTAR-------------------------ATKFLALDKCLPHRDFLQILEIEHDPSA-PDYLEYDIEWLTILRATDDLINVTGRLWNMPENNG--LHARWDYSATEEGMKEVLEKLNHDLKVPCNFSVTAACYDPS-----KPQTQMQLIHRINPQTTEFCAQLGIIDINVRLQKSKEE-HHVCG--EYEEQDDVESNDSGEDQSEYNTDTSALSS-INPDEIMLDEEED----EDSIVSAHSGMNTPSVEPS----DQASEFSAS----FSDVRILPGSMIVSSDDTVDSTIDREGKP--GGTVESGNGEDLTKVPLKRLSDEHEPEQRK----------KIKRRNQAIYAAVDDDDDDAA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T3E4-1", "uniprot_id": "DBR1_DANRE", "id": "Q7T3E4-1", "name": "Lariat debranching enzyme", "aln": "---MKVAVEGCCHGELDKIYESISYLENKDGVKVDLLLCCGDFQAVRNEGDMKCMAVPAKYRHMQTFYKYYSGEKKAPVLTIFIGGNHEASNHLQELPYGGWVAPNIYYLGYAGVIRYKGVRIGGLSGIFKSHDFKKGHFEFPPYN----PETLRSVYHIRNIDVFKLKQIKMPIDIFMTHDWPRGIYHYGNTNALLRQKKFLRQEVESSTLGSPAAADLLEHLQPSYWFSAHLHVKFAALMQH-------EAKN-NTAPK-------------------------ITKFLSLDKCLPHRDFLQIVEVADRPGS-SEQLEYDPEWLAILKATDNLQKPTCNFWNPPQDNG--LHSRWDFSASEEAMMEVVSDLSGDLCIPENFSLTVPPYDPS-----QPQPHALPAYSTNPQTTELCATLNLTDIYILAGQSGQIYGERGGKGATEEEDEEDSTGSADEPSDFPSDTSGLSSSYNPDEITIEDEWEEE--EDGGVGCGEGKGMDAVVPEGQVGSQDSDRDSSPQRETAKRLILPAPCAKPKTEAPLHSLPRLSLPPPSACVSQGSSEEEGAFTAARVPKRTSGETTQSSAGQTGGTPQIKRRNQSIYTAVEDEESDS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSD7-1", "uniprot_id": "DBR1_DROME", "id": "Q9VSD7-1", "name": "Lariat debranching enzyme", "aln": "---MKIAVEGCAHGELERIYDTIEGIEKVGGTKIDLLLCCGDFQSTRNLEDLQTMAVPKKYLDMCSFYKYYSGELVAPVLTIFIGGNHEASNYLQELPYGGWVAPNIYYLGYAGVVNVNGVRIAGISGIFKGHDFLRGHHEFPPYT----DSTCRSVYHVRQLEVFRLKQISGRVDIFLSHDWPTGIYEYGNKAQLLRKKPFFAADMESGKLGSQPLEELLKAVQPAYWFAAHLHCKFAALVPHNHSQKLGDAESSSSSSSSEDEDEEREKVKKAAPVPPPSKSVPVTKFLALDKCLPRRAFLQVVEVPSDPIEGTPRLEYDAEWLAILHSTNHLISVKENYYYLPGKKAGEFTERSNFTPTEEELEAVTAKF-QKLQVPENFERTVPAFDPAEQSDYKHMFVDQPKVQLNPQSNTFCATLGIDDPLCLVLLANGLDLPAVG---------------ATECKDRETKSSKLQA------------------------VEEDVAEPLVTPT------KRKLNLS----------LPAPTTAAADTTDENVIDLPEEE-----AEEAIIATETPHVEEPASVPASPNVKK-----------LKRRNQNIYQAQED------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24309-1", "uniprot_id": "DBR1_YEAST", "id": "P24309-1", "name": "Lariat debranching enzyme", "aln": "MTKLRIAVQGCCHGQLNQIYKEVSRIHAK--TPIDLLIILGDFQSIRDGQDFKSIAIPPKYQRLGDFISYYNNEIEAPVPTIFIGGNHESMRHLMLLPHGGYVAKNIFYMGYSNVIWFKGIRIGSLSGIWKEWDFNKQRPDWNDLENNNWKANIRNLYHVRISDIAPLFMIKHRIDIMLSHDWPNGVVYHGDTKHLLKLKPFFEQDIKEGKLGSPVTWQLLRDLRPQWWLSAHLHVRFMASIKH-------NKRSHEPPNK-------------------------STSKTKKNNNEIDLDLSSDEDERSGIMNCQEENEYDSKYGETRFLALDKCLPRRRWLEILEIEP---------DTSHASWKDENHRMFWDPEFINNLVICQKNKNLLS----NKPFNSVNWIELSQSNREEGRDIDWENYAIPAYTLDIQ---------------------KDEVRQTKAFISKFMT--------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::** **.**:*::**. : . :***: ****: *: *:: :*:* ** : * **..* *** *:*******: .:* **:**:** **:*:* :.*: .*:**..:***:* *: : : : . *.:**:* :: * :. :.*:::**** .: :*:. **: * *: :::...*** :**. ::* :*::**** :* * : * : . . *. :: : . : *** :: : . : .:. : . . *: : : . .. :. : : : : * : : ", "identical_positions": 92, "similar_positions": 111, "identity": "14.86%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2469", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TDP1-1", "uniprot_id": "RNH2C_HUMAN", "id": "Q8TDP1-1", "name": "Ribonuclease H2 subunit C", "aln": "MESGDEAAIERHRVHLRSATLRDAVPATLHLLPCEVAVDGPAPVGRFFTPAIRQGPEGLEVSFRGRCLRGEEVAVPPGLVGYVMVTEEK-KVSMGKPDPLRDSG-TDDQEEEPLERDFDRFIGATANFSRFTLWGLETIPGPDAKVRGALTWPSLAAAIHAQVPED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CQ18-1", "uniprot_id": "RNH2C_MOUSE", "id": "Q9CQ18-1", "name": "Ribonuclease H2 subunit C", "aln": "MKNPEEAADGKQRIHLRPGSLRGAAPAKLHLLPCDVLVSRPAPVDRFFTPAVRHDADGLQASFRGRGLRGEEVAVPPGFAGFVMVTEEKGEGLIGKLNFSGDAEDKADEAQEPLERDFDRLIGATGSFSHFTLWGLETVPGPDAKVHRALGWPSLAAAIHAQVPED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9QD20-1", "uniprot_id": "E9QD20_DANRE", "id": "E9QD20-1", "name": "", "aln": "MMTANSCVTS-----IRRDSIKQADKPQIHLLPCEVEHDGPAEVFKFFNPTVKERKHETTVSFRGRGLKGQELQCPQGYTGVVLKEVQK---------PASDQE--------------DRVVKVSSVFHHFTYWNLETPPTSDDGVVMAMAWPELAEAIHGPVDD-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . :... :* ::: * . :*****:* . ** * :**.*:::. . .***** *:*:*: * * .* *: :* * **.: .:. * :** *.*** * .* * *: **.** ***. * : ", "identical_positions": 50, "similar_positions": 39, "identity": "30.12%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2474", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P98199-1", "uniprot_id": "AT8B2_MOUSE", "id": "P98199-1", "name": "Phospholipid-transporting ATPase ID", "aln": "-----------------------------------------------------------------------------------------------------------------------------MTVPKEIPEKWARAG-----APPSWSQK-------------------------KPSWG------TEEERRARANDREYNEKFQYASNCIKTSKYNIVTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRHSQVLINGVLQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGD-VSQLARFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGTRFQVYLPWDEAVDSAFFS------GFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLG------------------------------------------HKAELGERP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EPVDFS-FNPLADKKFLFWDSSLLEAVKMGDPHTHEFFRLLSLCHTVMSEEKNEGELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHELGTAITYQLLAILDFNNIRKRMSVIVRNPEGKIRLYCKGADTILLDRLHPPTQELLSSTTDHLNEYAGDGLRTLVLAYKDLDEEYYEEWARRRLQASLAQDSREDRLASIYEEVESDMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFVVTGHTVLEVREELRKARKKMVDSSH------------------------------------------------------AVGNGFTYQGNLSSS--------------KLTSVLEAVAGEYALVINGHSLAHALEADMELEFLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFAEATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIALTTAVCIMPVVAFRFLRLSLKPDLSDTVRYTQLVR-KKQKAQHRCMR--------------RVGRTGSRRSGYAFSHQEGFGELIMSGKNMRLSSLALSSFSTRSSSSWIESLRRKKSD----SANSPSGGAEKPLKG-----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GJC6-1", "uniprot_id": "A0A8I6GJC6_RAT", "id": "A0A8I6GJC6-1", "name": "Phospholipid-transporting ATPase", "aln": "-------------------------------------------------------------------------MLSRTVGRPSFPLRVSHGLLEPCWVRWHCVQKSAPQATLRPRTVNAPFKNGIMTVPKEMPEKWARAG-----APPSWSQK-------------------------KPSWG------TEEERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNSRHSQVLINGVLQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETSELDGETNMKVRQAIPVTSELGD-ISQLAKFDGEVICEPPNNKLDKFSGALYWKGNKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGTRFQVYLPWDEAVDSAFFS------GFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLG------------------------------------------HKAELGERP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EPVDFS-FNPLADKKFLFWDPSLLEAVKMGDPHTHEFFRLLSLCHTVMSEEKNEGELYYKAQSPDEGALVTAARNFGFVFRSRTPKTVTVHELGTSITYQLLAILDFNNIRKRMSVIVRNPEGKIRLYCKGADTILLDRLHPSTQELLNSTTDHLNEYAGDGLRTLVLAYKDLDEEYYEEWARRRLQASLAQDSREDRLASIYEEVESDMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKARKKMVDSSH------------------------------------------------------AVGNGFTYQGNLSSS--------------KLTSVLEAVAGEYALVINGHSLAHALEADMELEFLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFAEATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTAVCIMPVVAFRFLRLSLKPDLSDTVRYTQLVR-KKQKAQHRCMR--------------RVGRTGSRRSGYAFSHQEGFGELIMSGKNMRLSSLALSSFSTRSSSSWIESLRRKKSD----SANSPSGGAEKPLKG-----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P98198-1", "uniprot_id": "AT8B2_HUMAN", "id": "P98198-1", "name": "Phospholipid-transporting ATPase ID", "aln": "-----------------------------------------------------------------------------------------------------------------------------MTVPKEMPEKWARAQ-----APPSWSRK-------------------------KPSWG------TEEERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGD-ISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFS------GFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLG------------------------------------------HKAELGERP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EPVDFS-FNPLADKKFLFWDPSLLEAVKIGDPHTHEFFRLLSLCHTVMSEEKNEGELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAITYQLLAILDFNNIRKRMSVIVRNPEGKIRLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAGEGLRTLVLAYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKAREKMMDSSR------------------------------------------------------SVGNGFTYQDKLSSS--------------KLTSVLEAVAGEYALVINGHSLAHALEADMELEFLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFADATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTVVCIMPVVAFRFLRLNLKPDLSDTVRYTQLVR-KKQKAQHRCMR--------------RVGRTGSRRSGYAFSHQEGFGELIMSGKNMRLSSLALSSFTTRSSSSWIESLRRKKSD----SASSPSGGADKPLKG-----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PDL2-1", "uniprot_id": "A0A8M9PDL2_DANRE", "id": "A0A8M9PDL2-1", "name": "Phospholipid-transporting ATPase", "aln": "--------------------------------------------------------------------------------------------------------------------MKRQWDN--MTIPKDIPEKWFPVI-----LPLKRKKEG-------------------LTSSTKIRKG------AEEERRVRANDREYNEKFQYASNCIMTSKYNIITFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVLVLSITAVKDATDDYFRHKSDNQVNNRQSQVLIGGILQKEKWMNVRVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQSLSVTSELGD-PNNLAQFDGEVVCEPPNNKLDRFCGTLYWRECKYPLSNQNMLLRGCVLRNTESCYGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAVWEKEVGALFQSFLPWDPPVDNFLFS------AFLSFWSYVIILNTVVPISLYVSVEVIRLGHSYFINWDRRMFCSRSNTAAEARTTTLNEELGQVEYIFSDKTGTLTQNIMTFNKCSINGHAYGEVVNIL---------------------------------------------AAQQKRV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QPLDFSSWNPLADRGFCFYDQSLLEAVMVGDPAVHEFFRVLSLCHTVMSEEKSEGELVYKAQSPDEGALVTAARNFGFVFRSRTPGTITTQELGKAVTYTLLAILDFNNIRKRMSVIVRNPEGRIRLYCKGADTVLLERLHSCNHEVMTITSDHLNEYAVDGLRTLAVAYRDLSEEQWDEWSERFRGADKATDCREDRLAAAYEEIEQDMMLLGATAIEDKLQEGVPETIAILSLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVNGHTVQSVREELRKARERMLESARTRDGGKEAEAQGWSGA-------------------------------------CAFGNGCGAGAAAAAANWAPDESKCPPAQAPPSSLLESISGEFALIISGHSLAHALEADMEREFLETACACRAVICCRVTPLQKALVVELVKRHKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFRFLQRLLLVHGRWSYLRMCRFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGIFDQDVPEQRSLEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVVLFFIPYSVLSHATQSNGVPLADYQTFAVTTATALVIVVSVQIALDTGYWTAINHFFVWGSLGTYFTILFAMHSSILFSIFPKQFHFLGSAHNTLGQPVVWLTIALATVICIAPVLAFRFLKLDLKPQLSDTVRYTQLVLQKKRKPGGRAARGVGSTGAAGGSGLGRLGRGGSRRSGYAFAHQEGFGELITSGKNMRLSSLALATFASRHSSSWIDTLRRKKHTNNTGAQNTPPTGDDITTSSQVPPISTASTPNVQQDSAAGDAGQASNEVAFTHSPEDIALSVVRDRDAGGCSAGSVQESAIVWKGIGARVSGANSPGPPPIEEETSYGE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGD4-1", "uniprot_id": "Q9VGD4_DROME", "id": "Q9VGD4-1", "name": "Phospholipid-transporting ATPase", "aln": "MIGGRRCSEAARRLRRRPDTLELSVLGGQPIETELQEDNERTPTKGAGNVDEPGIEAPEASCSAPSKRTRWFQFARSSKNRRKRLHCNEDEDVKQPERRNSDLEGSPRACLAQPEGMNIGSSTQTIATPLMIGDSFYSLAPGGGNPPPNKSDDQELYKQRDPSVTSESKSVPSLRRLSQIRRRRSSYYFSENERRIRANDKEFNAQFKYHNNYIKTSKYSLFTFLPFNLLEQFQRLANFYFLCLLVLQLIPAISSLTPVTTAIPLIGVLTLTAVKDAYDDIQRHISDSQVNNRKSKTLRNGKLVEAKWSEVQVGDVIRLDNNQFVAADTLLLSTSEPNGLCFIETAELDGETNLKAKQCLTETIELGDRHDSLWNFNGEIICERPNNLLNKFDGTLIWRGQRFALDNEKILLRGCVLRNTQWCYGVVVFAGVDTKLMQNSGKTQFKSTGVDRLLNFIIIGIVLFLVSICALFAIGCAIWEGLIGQHFQLYLPWEHIIPKDYIPTGATVIGLLVFFSYAIVLNTVVPISLYVSVEVIRFVQSFLINWDEEMYYPTTNTYAKARTTTLNEELGQIQYIFSDKTGTLTQNIMTFNKCSINGRSYGDVIDLRTGELVEITEQQTIFQNSNTNNRPSPLSGAIVAPPAAPPPIILVHKAEVHAKKTSMVVTSSGEAQVLPDRPRSDIERSAPPMDASEKRPGLKHVRYSAPSRSQDADAGRLSPRLDGSGGLSPPVGNEERRISGGFKRSGAGCMQRQLSRTSSCDKVKILHDSQQTETHNMHHSSHNRKRLVKIRFKKAPSTATLGVVISQLEHHLDEEPQSTSTLSTTKHHHHRSKAFATNWSSSPHRVHALQSVDFS-ANPHHESDFRWYDRTLLDAVRSDEEHSHVFFRLLALCHTVMAET-VDGKLEYQAQSPDEAALVSAARNFGFVFRTRTPNSITIEVMGQTEEYELLNILDFNNVRKRMSVILRRGDS-MVLYCKGADNVIYDRLHGGQEDLKARTQDHLNKFAGEGLRTLALAERRLTEQYYNDWRSRQQEAALSMDSREQKLNAIYEEIESEMQLVGVTAIEDKLQDGVPKSIANLQNAGIKIWVLTGDKQETAINIGYSCQLLTDELADVFIVDGNSVEEVEKQLRQFKESIKIYNRFRPGGFDPFDRLNSDSNMDPLSVTMTQTSAFMQETNLPPTPPPPPAISVVTFRWDEKNKDNKGGPDSAECNNLFGDEKGSEDGGTASIVVDENTGFALVVNGHSLVHCLSPELENKFLDIASQCKAVICCRVTPLQKALVVELIKRAKNAVTLAIGDGANDVSMIKAAHIGVGISGQEGLQAVLSSDYSIAQFRYLERLLLVHGRWSYYRMCKFLRYFFYKNFAFTLCHCWYSLFCGFSAQTVFDPMFISVYNLFYTSLPVLALGVFEQDVSDKNSLEFPRLYTPGLKSELFNIREFIYSVLHGAFTSLVLFLIPYGVYKDGVSANGFVVSDHMTLGAVVATILIVDNTAQISLYTSYWTVVNHVTIWGSLVWYFVLDYFYN-------YVIGGPYVGSLTQAMKDLTFWVTMLITVMALVAPVLAYKFYLLDVHPSLSDKIRQKSLKKIHSRASSDVRRTASS-----------RRGRR-SVRSGYAFAHQEGFGRLITSGKIMHKLPQDFA-FPLGLGTKKTQVLHNNLNS----ADGPNSKGNNVTGHHMVNNNTNMRHNQNQNHSSMADITADG-------------------RGNGGD------------DGRGSGGSDDMSPRAPCQDLDTINL-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * : :.: * . . . : :*:*** ****:*:* :*:* .* * ****.:.****.**:****.:** *** **:***** ****: .** :**: **::****** ** ** **.***.*:*:.* .* * : :* :* ***:*:*:******** ****:***:***:***:*******:*.:*.:. * **** ..* .*:**::** *** *::* *:* *: ::.*.*:::**********: *:*:*:*** *********:*:** *.:***:* ::: *. ***.: .::*** *:** :* ** :***: : . :. .:* *:** *:*****************: :*::****..*: ..* *:************::***************.********::**:*.:: * : :.:*** ** : * ::* :**:** .: * ***:*:******:* :*:* *:******.***:**********:*** ::* . :* : * ** ******:*******:*. :. : *******.:: :*** .:: * ****::* :*****.:* : * *: :::* * * : *.**::* : ***:*.:* *:*.********:***::** * *.**************:******::***::::**:* *::* .*.::**: :: : : * :: :*:: :**::.****.*.*..::* :**: *. *:************* ****:*: *:*****************:************:****:****::**::*:*********** ***:** **********: * *:.:*********:* **::**:.********:*:*:***.::.*:*:*:** ** . *** ***: .: :* :**:::*:***.* ... :* ::*: ::....** *:: :.**.* *.***.:**. :**** **.: : : : ::*. ::: : ..*:*: ::. : **:*::* *.::*.***.:* ..* :.: . * ** * ******:******.** *** *: . :: *. .:. : *:.: : .. . * : . ", "identical_positions": 608, "similar_positions": 339, "identity": "34.06%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2492", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q15637-1", "uniprot_id": "SF01_HUMAN", "id": "Q15637-1", "name": "Splicing factor 1", "aln": "MATGANATPL------------------------------------------------------------------------DFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIEDLTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALNPDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQ-----RPGDP-QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMP---PFGMPPAPPPPPPQN-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64213-1", "uniprot_id": "SF01_MOUSE", "id": "Q64213-1", "name": "Splicing factor 1", "aln": "MATGANATPL------------------------------------------------------------------------DFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIEDLTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHTLITEMVALNPDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQ-----RPGDP-QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPASNPPPPSLMSTTQSRPPWMNSGPSENRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGTPQMQGNPTMVPLPPGVQPPLPPGAPPPPPCSIECLLCLLSSPNSLCLSPNRAARIPPRGSDGPSHESEDFPRPLVTLPGRQPQQRPWWTGWFGKAA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IBT0-1", "uniprot_id": "A0A0R4IBT0_DANRE", "id": "A0A0R4IBT0-1", "name": "Branchpoint-bridging protein", "aln": "MATGANATPLGKLHPSIGAKRGFDSGPGPGLMPPPGPSVPFPLQNFQPPQLSNPGFPQFPGAVSSALSNPIVVGQQSQAGGGDFGQKKRKRSRWSSETPDQKTVIPGMPTVIPPGLTRDQERAYIVQLQIEDLTRKLRTGDLGIPVNPEDRSPSPEPIYNSEGKRLNTREYRTRKKLEEERHSLITEMVGLNPEFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECCAKIMIRGKGSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSTEPRSITNTTLCTKCGGAGHISSDCKFTSSFAPRPGEPPQSAQDKARMDKEYLSLMAELGEAPVPSSGGGHN----NAPPSGPRPSGPNNNQPPP-------NRPPWMNSGPTDNRNFHGMHQGP-----GGPHNFPPPMP----NMGGPPMPPNPNGMPPPWMQPPPPPMGQGPAPPGH-------------PMG------------LLPPPMGMMPPPPPPPNNQPPPPPSGPLPPWQQQ----APPPPPTSSMATSAPMPWQQNTTTTSTPA-TGNLPPWQQPQQTAASASQPPPPMGNPSMVPPPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPP-PPPMDPNFVTMMGIPG---MP---PYGMPPAPPPPPPQS-----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********** ** .********..:* :******************:************************** ************************:***********.******.***:************************************************* ***********************************************************************************************:*.*******:**********:***** ***:* **************************:* *. . .. .*.***:.* .* *** .*********::.* :**** * ****.** *:* . ** ** **** ************.*** **** *:* : **************..**************** .*****:****:*:*:*********:*.* **.:***** * :**::. .* ***:*** ***************** . :: :* . .* . . * . * : . * * * ", "identical_positions": 462, "similar_positions": 64, "identity": "63.2%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2508", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LTG6-1", "uniprot_id": "A0ABK0LTG6_RAT", "id": "A0ABK0LTG6-1", "name": "Radical S-adenosyl methionine domain-containing protein", "aln": "-----MVPSGVRTGRWVAAARAAQRRPRVDSLGQPPSPESARTRAALYVHWPYCEKRCSYCNFNKYIPRGVDEGAVRNCLVTEARTLLRLSGVQRVESVFFGGGTPSLASPHTVAAILEAVAQEVYLPADSEVTLEANPTSAPGPRLAAFGAAGVNRLSIGLQSLDDAELQLLGRTHSAREALQTLTEARHLFPGRVSVDLMLGLPAQKVKPWLQQLQKLLRHCDDHLSLYQLTLERGTSLFAQVQQGTLPAPDPDLAAEMYQEGRTVLRDAGFRQYEVSNFARNGALSNHNWTYWQCGQYLGIGPGAHGQFVPQGAGGHTREARIQTLEPDNWMKEVMLFGHGTRKCVPLSELELLEEVLAMGLRTDVGVTHQHWRQFEPQLTLWDVFGASREVKELLEQGLLLLDHRGLRCSWEGLAVLDSLLLTLLPQLQEAWQHRTPSPESGG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SUV1-1", "uniprot_id": "RSAD1_MOUSE", "id": "Q5SUV1-1", "name": "Radical S-adenosyl methionine domain-containing protein 1, mitochondrial", "aln": "-----MVPSGVRTGRWVAAARAAQRRPRVDSLGQPPSPESASTRAALYVHWPYCEKRCSYCNFNKYIPRGVEEGTVRNCLVTEARTLLRLSGVQRVESVFFGGGTPSLASPHTVAAVLEAVAQEVYLPADSEVTLEANPTSAPGPRLAAFGAAGVNRLSIGLQSLDDAELQLLGRTHSASDALRTLAEARLLFPGRVSVDLMLGLPAQKVEPWLQQLQKLLYHCDDHLSLYQLTLERGTSLFAQVQQGTLPAPDPDLAAEMYQEGRTVLRDAGFRQYEVSNFARNGALSTHNWTYWQCGQYLGIGPGAHGRFVPQGTGGHTREARIQTLEPDNWMKEVTLFGHGTRKCVRLGKLELLEEVLAMGLRTDVGVTHQHWQQFEPQLTLWDVFGASKEVEELLAQGLLLLDYRGLRCSWEGLAVLDSLLLTLLPQLQEAWQHRPSSPVSGG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HA92-1", "uniprot_id": "RSAD1_HUMAN", "id": "Q9HA92-1", "name": "Radical S-adenosyl methionine domain-containing protein 1, mitochondrial", "aln": "-----MALPGARARGWAAAARAAQRRRRVENAGGSPSPEPAGRRAALYVHWPYCEKRCSYCNFNKYIPRRLEEAAMQKCLVTEAQTLLRLSGVQRVESVFFGGGTPSLASPHTVAAVLEAVAQAAHLPADLEVTLEANPTSAPGSRLAEFGAAGVNRLSIGLQSLDDTELRLLGRTHSACDALRTLAEARRLFPGRVSVDLMLGLPAQQVGPWLGQLQELLHHCDDHLSLYQLSLERGTALFAQVQRGALPAPDPELAAEMYQRGRAVLREAGFHQYEVSNFARNGALSTHNWTYWQCGQYLGVGPGAHGRFMPQGAGGHTREARIQTLEPDNWMKEVMLFGHGTRKRVPLGRLELLEEVLALGLRTDVGITHQHWQQFEPQLTLWDVFGANKEVQELLERGLLQLDHRGLRCSWEGLAVLDSLLLTLLPQLQEAWQQRTPSPVPGG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4IGH2-1", "uniprot_id": "RSAD1_DANRE", "id": "A4IGH2-1", "name": "Radical S-adenosyl methionine domain-containing protein 1, mitochondrial", "aln": "MSTRVLTLTLLKKRHLMQCFWSTVGSVHLRSIASDKIP-SHAVEASLYVHWPYCLKRCSYCNFNKYISRSENHDTMTECLQKETETLLKLSQVSRITSVFFGGGTPSLAQPSTIAAVLETVTKNSNLSDLAEVTLEVNPTPAGKARLKDFTLAGVNRFSIGVQSLNADHLRILGRDHSVQHALQTVSEARKLCPGRVSVDIMFALPGQSVSCWQKQLEELLYVCDDHISLYQLTLERGTQLFKQVESGKLSVPGDEVTAIMYKTACRVLEESGFHQYEVSNFARNNAVSEHNMGYWRGHQYIGVGPGAHGRFVPHGDGGVQREARTQTLEPDVWIKEVQSRGRGTRRRITLHHLQLLEEVLVMGLRMNEGITHQHWELFSPEANLQQVFGKSANIQELQGGRFLILDDRGLRCSWEGLVLLDSILPTILLELEMFFHSRGIKRTQ--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . : . :: :: . . * . .*:******** ************.* :. :: :** .*:.***:** *.*: ************.* *:**:**:*:: *. *****.***.* .** * *****:***:***: .*::*** **. .**:*::*** * *******:*:.**.*.* * **::** ****:*****:***** ** **: * *..*. :::* **: . **.::**:**********.*:* ** **: **:*:******:*:*:* ** **** ****** *:*** *:***: : * .*:******.:*** : *:*****. *.*: .* :*** . :::** :* ** **********.:***:* *:* :*: :: * . ", "identical_positions": 228, "similar_positions": 106, "identity": "51.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2513", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "C0HKG5-1", "uniprot_id": "RNT2A_MOUSE", "id": "C0HKG5-1", "name": "Ribonuclease T2-A", "aln": "-MAPAEARGALPGWISVLGWGLALCSLCGAGPLWSG------------------------------------SHEWKKLILTQHWPPTVCKEVN--------SCQDSLDYWTIHGLWPDRAED-----CNQSWHFN-------LDEIKDLLRDMKIYWPDVIH--------RSSNRSQFWKHEWVKHGTCAAQV-------------DALNSEKKYFGKSLDLYKQIDLNSVLQKFGIKPSI-NYYQLADFKDALTRIY-GVVPKIQCLMPEQGESVQTVGQIELCFTKEDLHLRNCTEPGEQLSSRQEAWLAMEAS----THGMMVCED-GPIFYPPPTKTQH---------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZCH6-1", "uniprot_id": "D3ZCH6_RAT", "id": "D3ZCH6-1", "name": "", "aln": "---MAEARGALPGWVSVLGWGLALCCLCGAGPLWSG------------------------------------SHEWKKLILTQHWPPTVCKEVN--------RCRDSLDYWTIHGLWPDRAED-----CNHSWHFN-------LNEIKDLLRDMKIYWPDVIH--------PSSNRSQFWKHEWDKHGTCAAQV-------------DALNSERKYFGKSLDLYKQIDLNSVLQKFEIKPSI-NYYQLADFKDALTRIY-GVVPKIQCLMPEQGENVQTIGQIELCFTKEDFHLRNCTEPEEQPSSGQEARLAREAS----THGMMVCED-GPIFYPPP-KSQH---------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00584-1", "uniprot_id": "RNT2_HUMAN", "id": "O00584-1", "name": "Ribonuclease T2", "aln": "-MRPAALRGALLGCL-----CLALLCLGGADKRLRD------------------------------------NHEWKKLIMVQHWPETVCEKIQN-------DCRDPPDYWTIHGLWPDKSEG-----CNRSWPFN-------LEEIKDLLPEMRAYWPDVIH--------SFPNRSRFWKHEWEKHGTCAAQV-------------DALNSQKKYFGRSLELYRELDLNSVLLKLGIKPSI-NYYQVADFKDALARVY-GVIPKIQCLPPSQDEEVQTIGQIELCLTKQDQQLQNCTEPGEQPSPKQEVWLANGAAE---SRGLRVCED-GPVFYPPPKKTKH---------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8XY56-1", "uniprot_id": "RNT2_DANRE", "id": "B8XY56-1", "name": "Ribonuclease T2", "aln": "------MRFIAFAVI------FSAVYLCSS-AFTHP------------------------------------RGEWTKLILTQHWPQTFCKMEH---------CKTDFSYWTLHGLWPNTGVR-----CNTSWHFN-------ASLIEDILPEMEKFWPDLLE--------PSS--PKFWNYEWTKHGTCAAKS-------------ESLNSEHKYFGKALELYHKFDLNSVLLKNQIVPSE-KHYTLEDVEEAITSAY-GVKPKIQCVHPGQGGQVQILGQIEICVDR-DFQLMGCEKSSEDTWSNDLPTVPVSGQ-----SGLSVCDHSMPVYYPPVQA------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSC3-1", "uniprot_id": "Q9VSC3_DROME", "id": "Q9VSC3-1", "name": "", "aln": "MQSQRFLFVAILACFLVTIKSTPLSDISYSDESTSVNEKTQKRPDDDSEFDGFPFREDDDSLQDSSREMSVQDHNWDVLIFTQQWPVTTCYHWREENPDQECSLPQKKEFWTIHGIWPTKLHQMGPNFCNNSANFD-------PSKLNPIEDRLETFWPDLKG--------MDS-TEWLWKHEWQKHGTCAMLV-------------EELDNELKYFEQGLTWREEYIMSRILDASDIHPD--SNNTVAAINNAIVKAL-GKNPSIHCLYDGKHG-ISYLSEIRICFSK-SLELIDCDGIKQG--DAVPVGVPGGTII---TNCHIGSLVHYPSLVPPLQRKSHWKLPLVNVYKLLQFLMWFTL-------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02933-1", "uniprot_id": "RNY1_YEAST", "id": "Q02933-1", "name": "Ribonuclease T2-like", "aln": "-MLLKNLHSLLQLPIFSNGADKGIEPNCPINIPLSCSNKTDIDN------------------------SCCFEYPGGIFLQTQFWNYFPSKNDLN--ETELVKELGPLDSFTIHGLWPDNCHGGYQQFCNRSLQIDDVYYLLHDKKFNNNDTSLQISGEKLLEYLDLYWKSNNGNHESLWIHEFNKHGTCISTIRPECYTEWGANSVDRKRAVYDYFRITYNLFKKLDTFSTLEKNNIVPSVDNSYSLEQIEAALSKEFEGKKVFIGCDRHNSLNEVWYYNHLKGSLLSEMFVPMDSLAIRTNCKKDGIKFFPKGYVPTFRRRPNKGARYRGVVRLSNINNGDQMQGFLIKNGHWMSQGTPANYELIKSPYGNYYLRTNQGFCDIISSSSNELVCKFRNIKDAGQFDFDPTKGGDGYIGYSGNYNWGGDTYPRRRNQSPIFSVDDEQNSKKYKFKLKFIKN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: .* * . . :*:**:** ** * :: . :: :. .: :* :*: ***** : .** .: * * *. . : .: *: * * * . : ..:. .. .. .. . . ", "identical_positions": 26, "similar_positions": 45, "identity": "5.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2517", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LR97-1", "uniprot_id": "A0ABK0LR97_RAT", "id": "A0ABK0LR97-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQTFDPPNEGPLQGLVASRIETYGGR--HQTSAQSSAGITYPRGGPALDLS-RRRLQHYVPFAKGSGQTRGLSP---QEPDPEKRHGNYFGVGSPYFPKFKEVSK-------------------------------------------------------------------------------------------AHELEVRLHTFS-----------------------------------------------------------MFGMPRLPPEDRRHWEIGEGGDSALTIEKSWKELV-----------------------------------------------------LGHKEMNRELCHQQEALWELLTTELIYLRKLKIMTDLLAAGLLNLQRVGLLTEVSAETLFGNVPKLIRTHRRFWEEVLQPILEDTRTSGQPLDPVSLQNGFLTFGQRFQPYIQYCLRVKQTMAYAREQQDTNPLFRTFVQWCEKHKRSGRQTLGDLLIKPHQRITKYPLLLQAVLKRSPEPRAQLALDNMIVAVESFLQHINGLVRRGEEQESLMAVAQRIGPYEVLEPSSEEVEKHLRQFS-TLDLMTPIEGVAPENTRQLLLEGPVRMKEGREGKMDVYLFLFSDVLLVTK--PQRKVDKAKVIRPPLMLEKLVCRPLRDPHSFLLIHLTEFQCVSSALTVHCSSSTERTQWLQKTQQAQATLQKLKAEE----------YVQQKRGLLALYRDQGRESPSPRPSTPSP--EDSQSSAEGRALEF-TVIPRLVVTEDTD---------EDTPSVTDDTSDSGYGTLIPSSP------------------KDSQSPLNRLRSKALRRDPR----LTFSTLELRDVPLRPQPPDPQALQRRSAPEMPEGILRGGSLPRRAPPTWSEEEDETLTPGN----------------------VVVETLSRAQRRSPLPHSPAHTDSAGESPWEST--DEDEGPLSPGLRP---RSLRAEDMLREIREELASQRIEGALEPEPGNGKLRRLTRAQLQRMRGHHVIQLDTPMSTSDV--------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0J1-1", "uniprot_id": "PKHG6_MOUSE", "id": "Q8R0J1-1", "name": "Pleckstrin homology domain-containing family G member 6", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQAFGPPNEGPLQGLVASRIETYGGR--HQTSAHSTAGNLFPRGGPGVDPS-RRRLQHYVPFAKGSGQTRGMSPLVLREPDPEKRHGSYFGVGPPHSPKLKEVTR-------------------------------------------------------------------------------------------AHELEIRLHTFS-----------------------------------------------------------MFGMPRLPPEDRRHWEIGEGGDSALTMEKSWKELV-----------------------------------------------------LEHKEMNRQLCHQQEALWELLTTELIYLRKLKIMTDLLAAGLLNLQRVGLLTEVSAETLFGNVPNLIRAHRRFWEEVLQPILEDTRTSGQPLDPVSLQNGFLTFGQRFQPYVQYCLRVKQTMAYAREQQDTNPLFHTFVQWCEKHKRSGRQTLGDLLIKPHQRITKYPLLLQAVRKRSPEPRAQEALNAMIEAVESFLRHINGQVRQGEEQESLMAVAQRIGPYEVLEPSSEEVEKNLRPFS-TLDLMTPVLGVAPEYTRQLLLEGPVRVKEGREGKMDVYLFLFSDVLLVTK--PQRKADRAKVIRPPLMLEKLVCRPLRDPNSFLLIHLTEFQCVSSALTVHCPSSTERARWLEKTQHAQTTLQKLKGEQ----------YIQQKRELLALYRNQGTESPSTRPSTPSPSPEDSQSSAEGRTLEF-AIIPRLVVTEDTD---------EDTPSMPDDASDSGYGTLIPSSP------------------KDSHSPLNRLRSKALRRDPR----LTFSTLELRDVPLRPQPPDPQAPQRRSAPELPEGILRGGSLPRRAPPIWSEEEDETLASGN----------------------VVVETLHRAQRRSPLPHSPTHTDSAGESPWESS--DEDEGLLSPELRP---RSLR-EDMLREIREELANQRIDGASEPEPGNGKPRRLTLAQLQRMRVPHIIQLDTPLSTSEV--------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3KR16-1", "uniprot_id": "PKHG6_HUMAN", "id": "Q3KR16-1", "name": "Pleckstrin homology domain-containing family G member 6", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKAFGPPHEGPLQGLVASRIETYGGR--HRASAQSTAGRLYPRGYPVLDPS-RRRLQQYVPFARGSGQARGLSPMRLRDPEPEKRHGGHVGAGLLHSPKLKELTK-------------------------------------------------------------------------------------------AHELEVRLHTFS-----------------------------------------------------------MFGMPRLPPEDRRHWEIGEGGDSGLTIEKSWRELV-----------------------------------------------------PGHKEMSQELCHQQEALWELLTTELIYVRKLKIMTDLLAAGLLNLQRVGLLMEVSAETLFGNVPSLIRTHRSFWDEVLGPTLEETRASGQPLDPIGLQSGFLTFGQRFHPYVQYCLRVKQTMAYAREQQETNPLFHAFVQWCEKHKRSGRQMLCDLLIKPHQRITKYPLLLHAVLKRSPEARAQEALNAMIEAVESFLRHINGQVRQGEEQESLAAAAQRIGPYEVLEPPSDEVEKNLRPFS-TLDLTSPMLGVASEHTRQLLLEGPVRVKEGREGKLDVYLFLFSDVLLVTK--PQRKADKAKVIRPPLMLEKLVCQPLRDPNSFLLIHLTEFQCVSSALLVHCPSPTDRAQWLEKTQQAQAALQKLKAEE----------YVQQKRELLTLYRDQDRESPSTRPSTPSL--EGSQSSAEGRTPEFSTIIPHLVVTEDTD---------EDAPLVPDDTSDSGYGTLIPGTP------------------TGSRSPLSRLRQRALRRDPR----LTFSTLELRDIPLRPHPPDPQAPQRRSAPELPEGILKGGSLPQEDPPTWSEEEDGASERGN----------------------VVVETLHRARLRGQLPSSPTHADSAGESPWESSGEEEEEGPLFLKAGHTSLRPMRAEDMLREIREELASQRIEGAEEPR--DSRPRKLTRAQLQRMRGPHIIQLDTPLSASEV--------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ATA9-1", "uniprot_id": "A0A8M3ATA9_DANRE", "id": "A0A8M3ATA9-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDTVKSSNPSNPQEVNNVMAPEETALGEKSDRQRQENNEPDVDAPDGFVAVASTGQRRAQEKHRYNTIGYQKKKQRTNVDFSTVSKGAGVKSRGALKQVLFNQGTNDK-------------------------------------------------------------------------------------------NGTVEERLGGVQGQVDV-----------------------------------------------------LKQLLDSFSVPADLRWTWGEGG-TERAVEKSWTEIV-----------------------------------------------------HSHESMSKTQRLQQEALWELLNTELTYINKLTIAKDLVLAALSYCHLNGFLQEVSPTMLFSDLPSILDAHRLFWHDVMYPMLQEVRLTGRPFDPMKLEPGCLQFHKRFPAYFDYCFEGDRNVELTRKQLETNPQFYTYLMWVENHPQCGRMRLGDMQAKPHQRITKYPLLLKAVQKTTEDLPAKIALDRMLNSVNNFVQSINDYLQLKADELALSAIAQRIEGYKIEG-LSEEVDKHVREIC-RFDLTSPMSGVGPNVIRKQILEETLKVKR-RKDTKEFVVLLFTDVLLITK--AQKKSDKLKVLRPPMLVERIHCIEVKDGYSFMLVEVGDLGCPLSVHIMSTPSPDSCASWVSALRETQEALQKLKINEKNAILKNTHTVPDKDADFHTAYYSDIDPEEMVQQIYPTSQSDSDSDPADNERSTFSKVDPHTLMDVEQSKVQQMSDYRSSSLTEPDDQSQSGYEEVVGKTDSVGLNAEQGKSRINSNQWEDEEASLKNIQERRVTWTQKQQTPSNSNDLTQQELPIRNNLNGPAGHVKDTIQPLITTSAHGTSVETGEPMHLDPDSDSQESRRNSLCSQQEDDEESLTESKRFSRKLKSPRIQRRRLNNAQPNGMGFASDANSSRSQKNKSQDSHRVLKLGSLK---NNPSTLWYVPEKRSPKRSPTQEMHSEPEQTPEEKRKLKLIKLKTQRSASIPEISIPQTSIPPSQITSSSLLTAPDPQPPTSPLQSVLQRAKEREKERGLGRKVVKEKEKTFSIQNSPTISASSSLSASEGERETEREESAEPSVMFAHGWREGNVDGSEDEMKESSNVLEGISVDWPGWCFDDEEFFDFEDLDYENWFEQSLTSNGVRRSKTKRSEGHDDNEWSEV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VW85-1", "uniprot_id": "Q9VW85_DROME", "id": "Q9VW85-1", "name": "DH domain-containing protein", "aln": "MGGGFAAPPITLASNQRPVALDQVEIPIPATDMHEKLLEKEGKTERTNLLGRSKDKPPKDKPPKQSKFAERLRRSFRRGDHRSLEIKRQEPTPEELKAKSRATPPPPSTLRSDNNNRLPFALSHLNLPGLGLGVGVGVGGHINPALLLDSPDECTPPEYAYQHLSSVATTNSSTSLESSCELGELSGSQNSVYYWASMGGEVSTSAGAAGADGTAGTGAGTGAGAGAAVPIEGQDRRRLETQNSSRSDQQPITTNASSAPGNSSRSCSLTSDSSSIRLTRLQNFLFKSSNESSRSCQGHSNEGFTVSSHNSSSGEWEQLGAYLSSSSGVGGGHDFQGGSFPEESTPDETDGTLPVETSSSGGGGGYYQYTLTSPNNPFLPEITARTYHSTYGEDGAVEGGEPTTDDLQLDGKYGCAGSRSAQLPTPSYSRAGSQESTHSEGGGPPGPTPSPASSSSSTPGRHRRKLFSLNSPTRLLHHQQQQPPPSGATSASPPSGGSSNDGGGGKFNSASLVRSLNPFLPSVTSPKKAPHKQSAVTSPGCLTPDLSTKREEFLRATMKICLVVSPPNSKLQLKSKSLTHLDGLDSGVVACQQGPPGMATSTASTTATTAGGTGATTGLFATTGAPGSLGRQANVTEKGERTGVCLSPSAPQPSSHASPHHPPTIYTQAPQVVRRMPSLMLSPTLDETTTTASSSCFGTGHPSAGSFHQHQHHHHHHQPTGSVSTASCTATSTTSTHAVPSSKHFQSVGEAAATSSSSTLSPHSATSATLGGGGGGGGAGGGGLTSPVGCSTSSGSTVKKKSSFMKRKKPLLTRSEVSSSEFFSVSFCLDSSQQPDEEFIPATKGVTLLNALSHALRRRNLSFTQITITDNNPTPSFLDAGPSLLPVSVDEQTDVESLAGHHLCITERGSNRKPLQKAASFGSRQPPPRLLPSVSTEETSESGVAPGKQIKQRWSSIFGIKNPQQSQLCELLNSYAKNGVPQRPDSMSFDHPDLVNSLAYLQYMHKSWRDFVNSDSMSESEVKIQTAIWELVTTEVYYIHALQTVTDLFLACLEAVQEEGLLIDVDQARLFSNVRAVCEANIKFWTLWLYPMVAHSAITHEPLRCAFFQEGFLSFASIFAPYKIYCAEQSTCQFYCKELNHNNALFTSYLAWCESQKMCNRLRLADIVVRPMQRLTKYSLLLAAIKKHMSDVEEIEAIDVMMHSVENFVGSVNNHLTMRQENERLKGVMVRIESYDVVDTNNEVLDKMIKQNSQMFDLCAPMRGCPAYHVRHLFMEGDHKFKD-NLGKSDVHCFLLTDLLLVCKTIAKRGLGALKVIRQPYLTDQLIVQLAPN-NTLNCVYLNEFQVATTAFTLQCTEAKN---WYDALWRAKTIYQRLKRGGGGG------GSGSGTVGGGDSFRFGGSATSGGTADSLGVRKSPMNSSICSHVSSANNSHSGSVEWNDSR------NISVDFEKTNSVSSDEGSSIMTGNHG---------------VNLKGKQQLISGLHKTKMGIIGQMG---SKSANTLSVQPMNHLGQSLPNLNMHHSHTNNTLLVPGSTTSHSGNMLLSPSHRGISYPPPS---------------------PTRVPLRRGMAFSTSTKNPPLRKTRNITSQNSINWHQIPATPTPPSPRSQYQSPGVVCMQKSLPLLLPTNTDEGQGPTQPPPPLQKQLSHQAPLPTTIHNQSSTETDV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. *. :. . : . .. * ::: :. . . . .. . .. . :. * . : . .* . ::: * .:. ..*.. * *:***:.**: *:. * .**. * * : *:* :*. **.:: : :: ** : * : . : .*: :: * * * . * .* ** . . :: ..*. * ::: * *.: ..* * *: :* **:***.*** *: * : *:: *: :*:.*: :*. : :: * . ** *.: .: ::* :: . :** :*: * . *: ::* :.* . .. :. :*::*:**: * .:: . **:* * : ::: : :: : : :: :. : ... . * . .:: *:** . : . ... .. . : : . . *:.* : ... :. ::. : : . . *:. . * : . . : * . . . . . : :. .: . . . : .. ::*. . . ", "identical_positions": 89, "similar_positions": 214, "identity": "4.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2523", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V969-1", "uniprot_id": "G3V969_RAT", "id": "G3V969-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAWALKLPLADEVIESGLVQDFDASLSG------------------IGQELGAGAYSMSD-------------------VLALPIFKQEESSLPP-----------------ENENEILPFQYVLCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKLGELPEINGKLVKSIFRVVFHDRRLQYTEHQQLEGWRWNRPGDRILDIDIPMSVGVIDPRANPT--QLNTVEFLWDPAKRTSVFIQVHCISTEFTMRKHGGEKGVPFRVQIDTFKENENGEYT-------------------------------------EHLHSASCQIKVFKPKGADRKQKIDREKMEKRTPHEKEKYQPSYETTILTECSP-------------------WP-----------EITYVSNSPSPGFNSSHSSFSLGEGNGSPNHQ---------PEPPPPVTD----NLLPTTTPQEAQQWLHRNRFSTFTRLFTNFSGADLLKLTRDDVIQICGPADGIRLFNALKGRMVRPRLTIYVCQESLQLREQPQQPQPQ-QKQEDGD-SNGTF-FVYHAIYLEELTAVELTEKIAQLFS---------------ISPQQISQIYKQGPTGIHVLISDEMVQNFQEEACFILDTMEAETSDSYHVILK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERA0-1", "uniprot_id": "TFCP2_MOUSE", "id": "Q9ERA0-1", "name": "Alpha-globin transcription factor CP2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAWALKLPLADEVIESGLVQDFDASLSG------------------IGQELGAGAYSMSD-------------------VLALPIFKQEESSLPP-----------------DNENEILPFQYVLCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKLGELPELNGKLVKSIFRVVFHDRRLQYTEHQQLEGWRWNRPGDRILDIDIPMSVGVIDPRANPT--QLNTVEFLWDPSKRTSVFIQVHCISTEFTMRKHGGEKGVPFRVQIDTFKENGNGEYT-------------------------------------EHLHSASCQIKVFKPKGADRKQKIDREKMEKRTPHEKEKYQPSYETTILTECSP-------------------WP-----------EITYVNNSPSPGFNSSHSSFSLGEGNGSPNHQ---------PEPPPPVTD----NLLPTTTPQEAQQWLHRNRFSTFTRLFTNFSGADLLKLTRDDVIQICGPADGIRLFNALKGRMVRPRLTIYVCQESLQLREQQPQPQPQPQKQEDGD-SNGTF-FVYHAIYLEELTAVELTEKIAQLFS---------------ISPHQISQIYKQGPTGIHVVISDEMVQNFQEEACFILDTMEAETSDSYHVILK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12800-1", "uniprot_id": "TFCP2_HUMAN", "id": "Q12800-1", "name": "Alpha-globin transcription factor CP2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAWALKLPLADEVIESGLVQDFDASLSG------------------IGQELGAGAYSMSD-------------------VLALPIFKQEESSLPP-----------------DNENKILPFQYVLCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKLGELPEINGKLVKSIFRVVFHDRRLQYTEHQQLEGWRWNRPGDRILDIDIPMSVGIIDPRANPT--QLNTVEFLWDPAKRTSVFIQVHCISTEFTMRKHGGEKGVPFRVQIDTFKENENGEYT-------------------------------------EHLHSASCQIKVFKPKGADRKQKTDREKMEKRTPHEKEKYQPSYETTILTECSP-------------------WP-----------EITYVNNSPSPGFNSSHSSFSLGEGNGSPNHQ---------PEPPPPVTD----NLLPTTTPQEAQQWLHRNRFSTFTRLFTNFSGADLLKLTRDDVIQICGPADGIRLFNALKGRMVRPRLTIYVCQESLQLREQQQQQQQQQQKHEDGD-SNGTF-FVYHAIYLEELTAVELTEKIAQLFS---------------ISPCQISQIYKQGPTGIHVLISDEMIQNFQEEACFILDTMKAETNDSYHIILK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q1I0-1", "uniprot_id": "A0A8M1Q1I0_DANRE", "id": "A0A8M1Q1I0-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAWALKLPLADEVIESGLVQDFDASLSG------------------IGQELGAGAYSMSD-------------------VLALPIFKQEESNLPP-----------------ESDNKILPFQYVLCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKMGELPEINGKMVKSIIRVVFHDRRLQYTEHQQLEGWRWNRPGDRILDLDIPMSVGVVDPRANPT--QLNTVEFLWDPSKRTSVFIQVHCISTEFTMRKHGGEKGVPFRIQIDTFKENEAGEYT-------------------------------------EHLHSASCQIKVFKPKGADRKQKTDREKMEKRAPQEKEKYQPSYETTILTECSP-------------------WP-----------EATYVNNSPSPGFNSTHNSFPVTEGNGSPSHQ---------PEPVAQLADVS--NLLPTATPQEAQQWLHRNRFSPFCRLFTNFSGADLLKLTREDVIQICGPADGIRLFNALKGRVVRPRLTIYVCQESQQAREQH-------QKHENGDGTNNTF-FVYHAIYLEDLTAVELTEKLAQLFS---------------ISPRQISQIFKQGPTGIHVLVSDEMIQNFQDEVCFVLDTMKAETNDGYHIILK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z851-1", "uniprot_id": "A1Z851_DROME", "id": "A1Z851-1", "name": "", "aln": "MALSFLSQNSGLLDLQSIFDPQYTHHQQQQQQLLHLSHHPQHHIQQHQNQQLQQQAEQIQQHQQERTLSTKFDLNLFNELDQMEFNNLNRSQYQNNNNNNSISNNQNSNNNTNTTNGISENLNQIQNRHFISGYHHQHIGSDYEQVINFVDSPPNSEESWTESSSLIEQITIVVDGQSKDSPGPQIIDVQTIYLNSGSRKRRMDWDSLDIGQSENSPTASQSGDLPSKVAHQEKEKHKREKHSGRSSWSDDIGFDLNAEFNSNSYLNNENFLSFSPTLTTLKQEPQTDQIKPSPKVSLDNASASPSIAIAKLDEVQNSPSQAISGQDSANGSGSAANGKHDVNSGLACGCGSPQGSPLANAEYELNEKGKPQQLSVLDPAKIEIGSANGATHAEDHKFQYILAAATSIATKNNEETLTYLNQGQSYEIKLK---KIGDLSLYRDKILKSVIKICFHERRLQFMEREQMQQWQQSRPGERIIEVDVPLSYGLCHVSQPLSSGSLNTVEIFWDPLKEVGVYIKVNCISTEFTPKKHGGEKGVPFRLQIETYIENTNSATASGSGGSNNSAIASGSGSSGSAAPASPERTPSAGSNGKQAVHAAACQIKVFKLKGADRKHKQDREKIQKRPQSEQEKFQPSYECTIMNDISLDLVMSATTTGCYSPEYMKLWPNSPVHIPKYDGMLPFAPSAASPATSSSPIAINSVTSTNSPTLKLMDATNMVSPQHVPADMDDYSQNIMPESTPSQVTQWLTNHRLTAYLSTFAQFSGADIMRMSKEDLIQICGLADGIRMFNILRAKTIAPRLTLYASVDGCSYNAIYLLSNTAKELQQKLFKMPGFYEFMAKASAQENGAGGAATAAAAALFNNWGMHSKYSGSGSNIFNDANKSCVYISGPSGILVTITDEVLNNEIKDGSLYALEVQAGKVILKLINKQDNN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : * :*:: * *. :** * **: . *: * :: ** . :: :*.. * .. : ***:*.**** *.* ::**************:: *:*:*. ..*::**:::: **:****: *::*:: *: .***:**:::*:*:* *: . : .*****::*** *...*:*:*:******* :***********:**:*: ** . : : :*:*:******* ******:* ****::**. *:**:***** **:.: * ** .:. .:.**. .*: :: ...**. : *: . * *::* :**.:. *** .:*::.: *::*****:::::::*:***** *****:** *:.: : ****:*.. :. . . : ::. . : *: :* *: :. * * **. :. : * :: .**:** * ::**:::* .: .: ::* . : : ", "identical_positions": 190, "similar_positions": 170, "identity": "20.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2527", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q49AM3-1", "uniprot_id": "TTC31_HUMAN", "id": "Q49AM3-1", "name": "Tetratricopeptide repeat protein 31", "aln": "MAPIPKTVGRIKLDCSLRPSCPLEVAAAPKLCKEFGPEDYGEEDIVDFLRRLVESDPQGLHRIHVDGSSGRLQLWHHDYLLGHLDDEGKSTGQ-----SDRGKGAEGLGTYCGLRKSFLYPPQESEPCPQSPSASATFPSVSDSLLQVAMPQKLLVTEEEANRLAEELVAEEERMKQKAEKKRLK---KKRQKERKRQERLEQYCGEPKASTTSDGDE--SPPSSPGNPVQGQCGEEEDSLDLSSTFVSLALRKVGDWPLSARREKGLNQEPQGRGLALQKMGQEEESPPREERPQQSPKVQASPG----LLAAALQQSQELAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQETLRGGS--QPDAARELRSCLLHLTLQGQ-RGGICAPPLSPGALQPLPHAELAPSGLPSLRCPRSTALRSPGLSPLLHYPSCHRSHPNQPLSQTQSRRPHPLKPQDPSKGWDILGLGLQHLSQAR------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58H152-1", "uniprot_id": "A0AC58H152_DANRE", "id": "A0AC58H152-1", "name": "", "aln": "----MRMRAAVSERCVVCAKVGKNLEKRVRLKDYFLLQNDERLMRTHEAMVDMINDRPANRNILDALSFGYKYVPELDHFAAQFPGYEDSSDEDYYYYDDDKYSSHTNNRYCGFSRNFLDRGLPKPITAEEAERNAKELVDEEEKIKKKAEKKKMKKMRQKERRRLEKLEKENANKEKNKPVQVDPGPEKTKHADKDNENKDKKCKNKGCSSVPPDPQPISAPVSSSDSSSDEEDDKKEDSAIEPEELDMNSCFVSNAAAIAKRKLEQKPKPDKKPAQANPKKQHESQQKATVMPQKQVAKEEVNGEESVNANDFITRSVELAVIGNEYAGSGNMEMAVKYFTDAIKHNPKEYKLFGNRSYCYEKMLQYEKSLTDAEIALSMNPKWIKGLYRKGRALVGLKRYNEARLTFGEVLKLDSSCKDAAEEIMRVQLMQLMEMGFTKEQSSNALIIHGTVERALESLSGLSGLAPVLVPKENEFKS----VQYKHPQPPAKFPLMPLPQNQPRPSMPTAAPLPPHSPELFPIWVGDLVSSITGSKLYDLFKSVGNIHNVRVLPDRYCAFVNYTSKDSCEKAIQMFNGHAIDGTTLVVRYPDRIHTRLGMSRDASTESSGKNGKQPNECYFWRMYGCKNERCTFKHIPENKGIDRPKAKPHT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :. * : .. :: :* . * :: . .. : .* . :.* * * : . *:: .:: . .*:.: .* .:. . ***: :.** . .:... .*. .:. :: :* : . .: :* * : :*: *:* : ::. :* :: * :*. :: * : .*:.. . : *.* *..:. ..: .::::. :.. :.: *.: . *:*: : :*: : : *.*.. **:. : * : :* *** :*..:* .* . ** **:*:* **::::******:*:*:: * :*:**::**::.* * :**:* *:**:**:*:.** .* *.*: .* : * . :* *::* * : . . : *::: .: . ***..: *:.. ::* ::*. ..* **.*.*.* . * . *.:. ::: : : .* .: ", "identical_positions": 106, "similar_positions": 198, "identity": "16.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2535", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43572-1", "uniprot_id": "AKA10_HUMAN", "id": "O43572-1", "name": "A-kinase anchor protein 10, mitochondrial", "aln": "MRGAGPSPRQSPRTLRPDPGPAMSFFRRKVKGKEQEKTSDVKSIKASISVHSPQKSTKN-HALLEAAGPSHVAINAISANMDSFSSSRTATLKKQPSHMEAAHFGDLGRSCLDYQTQETKSSLSKTLEQVLHDTIVLPYFIQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQSSLAEPVSPSKKHETTASFLTDSLDKRLEDSGSAQLFMTHSEGIDLNNRTNSTQNHLLLSQECDSAHSLRLEMARAGTHQVSMETQESSSTLTVASRN-SPASPLKELSGKLMKSIEQDAVNTFTKYISPDAAKPIPITEAMRNDIIARICGEDGQVDPNCFVLAQSIVFSAMEQEHFSEFLRSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDLIHSVRGDEFLGGNVSLTAPGSVGPPDESHPGSSDSSAS--QSSVKKASIKILKNFDEAIIVDAASLDPESLYQRTYAGKMTFGRVSDLGQFIRESEPEPDVRKSKGSMFSQAMKKWVQGNTDEAQEELAWKIAKMIVSDIMQQAQYDQPLEKSTKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88845-1", "uniprot_id": "AKA10_MOUSE", "id": "O88845-1", "name": "A-kinase anchor protein 10, mitochondrial", "aln": "MRGAGPSPRHSPRALRPDPGPAMSFFRRKVKGKEQEKTLDVKSTKASVAVHSPQKSTKN-HALLEAAGPSHVAINAISANMDSFSSSRTATLKKQPSHMEAAHFGDLGRSCLDYQTQETKSSLSKTLEQVLRDTVVLPYFLQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQSSLAEPVSPSKRHETPASSVTEALDRRLGDSSSAPLLVTQSEGTDLSSRTQNPQNHLLLSQEGHSARSLHREVARTGSHQIPTDSQDSSSRLAVGSRN-SCSSPLRELSEKLMKSIEQDAVNTFTKYISPDAAKPIPITEAMRNDIIAKICGEDGQVDPNCFVLAQAVVFSAMEQEHFSEFLRSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPLRQAWTTMEKVFLPGFLSSNLYYKYLNDLIHSVRGDEFLGGNVSLAAHGSVCLPEESHSGGSDGSTA--QSSVKKASIKILKNFDEAIIVDAASLDPESLYQRTYAGKMSFGRVSDLGQFIRESEPEPDVKKSKGFMFSQAMKKWVQGNTDEAQEELAWKIAKMIVSDVMQQAHHDQPLEKSTKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QDF6-1", "uniprot_id": "F1QDF6_DANRE", "id": "F1QDF6-1", "name": "", "aln": "----------------------MSFFRRKAKGKEPERPADAKASKAPVSPHSPSLSGRNHHAILEAAGPSHVAISAISANMDSFARGRTAILKKQPSHMEAAHFGDLGRSSVNYQIQETRSRLSKTVDQILRDNVALPYFIQFMETRSAEHLVRFWLEAESFRSTSWSRVRAHSLNSVKHSTLAEPAAALGSPDSPDSPNHSSRPLNLDEGDEEDAFSSRTSSRPHTPSPQDTNSHSGALMSHRDSVSFD-GTAQPGTLQLQPALRSETPTRQTSSRTGTPVKGLRELSDKLMKSIERDAVNIFTKYISPDAARPIPITEQIRNDIVAKICGEDGQVDPNCFVIAQSVVFSIIDQQHFTEFLRSHYFCKYQIEVLTSGSVFLADILFCESALFYFSEYMEKEDAMNVLQFWLAAENFQDQLAAKKGQYDGQEAQNDAMILYDKYFSLQATNPLGFGDSVRMEIESNICREGGPLPDCFNTPLRQAWTTMEKVYMPGFLSSNLYYKYLSDLINSVRVDEFIGGNANTPNQGWTQ-EGERNSSVTEGSHVQLQQGTKKAAIKILKNFDEAITVDIASLDPESLYQRPYAGRMTFGKVNELGQFIREAEPEPDVKKSKGSMFSLAMKKWVQGNSDEAQEEMAWKIAKMIVNDVMQQGHHGSPEVKATKL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *******.**** *:. *.*: **.:: ***. * :* **:***********.*********: .*** *******************.::** ***:* ****::*:*:*.:.****:**** * ****:********:**:***:******:**:*:****.:. ::. * .: .* :... : :::.. . .:..:.* . .: *: *:.*: *: :..:. ..**. : . *:*** *******:**** **********:****** :****:*:**************:**::*** ::*:**:******:************:*:***********************:*:*******:***.*******************************:****.* **:**************:**.*************::*************.***:*** ***:***.. . * . * :.. ::.* *...***:*********** ** ***********.***:*:**:*.:*******:******:**** *** *********:******:*********.*:***.::..* *:***", "identical_positions": 420, "similar_positions": 139, "identity": "63.06%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2537", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CJ26-1", "uniprot_id": "NRADD_MOUSE", "id": "Q8CJ26-1", "name": "Death domain-containing membrane protein NRADD", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MLYNVSKGVVYSDTALQ----------------------------------------GQDGDREGMWVG-------AGGALAPNTSSLFPPEPPGASSNIIPVYCALLATVILGLLAYVAFKCWRSHKQRQQLAKARTVELGDP-DRDQRRGDSNVFVDSPPSLEPCIPSQGPHPDLG--CQLYLHIPQQQQEEVQRLLMMGEPAKGWQELAGHLGYQAEAVETMACDQMPAYTLLRNWAAQEGNRATLRVLEDALAAIGREDVVQVLSSPAESSSVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F8D4-1", "uniprot_id": "E7F8D4_DANRE", "id": "E7F8D4-1", "name": "", "aln": "MKGATEALQLCFYVLAVKMAFGKTCTSEQFTKTGECCSMCAAGTGLVTSCGQEDTKCQPCQDGVSFSDSESLLSCTLCAHCPIGIPQLARCTKTQDTRCDCGEHFFLWRDGNSTGGLCAPCRKCGPGWGVSQACGLLGDTKCELCKPGTYSKDTSDRKPCVPCSRCQDEEVEIRPCLPDSDTVCMVKDLNILSRPSGSDGPRETPRLQTPNEETESGISPAPGSGAPRLTPQDQGGNNNILVYVSVLAAVVLGLLLYVAYKCWKSCQQKQALVKARVGELNNAGEGEKLHSDSGVFLDS-HSLQESQPSKGSKRDSKQDTRLYINLPPHRQEEVEGLLAEGG-NRSWKQLAATLGYEQERVDVFGRGQDPIHTLMTDWSQQEG--STLGLLCSALTRIERPDIITALTAPTQGVSVV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.* .**. : : *.** ** : :* : **.:.: . ...* * ** ::**:*:**** ***:***:* :*:* *.***. **.:. : :: :.**.**:** **: . **:*.: * :**:::* ::****: ** * :.*::**. ***: * *:.:. .* * :**: :*: *** :** :* .**: * * *:: .*::*::. ***", "identical_positions": 88, "similar_positions": 78, "identity": "21.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2538", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M824-1", "uniprot_id": "SHC1_RAT", "id": "Q5M824-1", "name": "SHC-transforming protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MNKLSGGGGRRTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGAKGAMRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEE---ELPDHQYYNDFPGKEPPLGGVVDMRLREG----AARPTLPSTQMPSHLGATLPIGQHVTGDHEVRKQMLPPPPCPGRE--LFDDPSYVNIQNLDKARQAGGGAGPPNPSVNGSAPRDLFDMKPFEDALRVPPAPQSMSMAEQLQGESWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVDRKV-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P98083-1", "uniprot_id": "SHC1_MOUSE", "id": "P98083-1", "name": "SHC-transforming protein 1", "aln": "MDLLPPKPKYNPLRNESLSSLEEGASGS-----------TPPEELPSPSASSLGPILPP---LPGDDSPTTLCSFFPRMSNLKLANPAGGRLGPKGEPGKAAEDG-EGSAGAALRDSG--------LLPLL------------QDMNKLSGGGGRRTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEE---EPPDHQYYNDFPGKEPPLGGVVDMRLREG----AARPTLPSAQMSSHLGATLPIGQHAAGDHEVRKQMLPPPPCPGRE--LFDDPSYVNIQNLDKARQAGGGAGPPNPSLNGSAPRDLFDMKPFEDALRVPPPPQSMSMAEQLQGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVDRKV-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29353-1", "uniprot_id": "SHC1_HUMAN", "id": "P29353-1", "name": "SHC-transforming protein 1", "aln": "MDLLPPKPKYNPLRNESLSSLEEGASGS-----------TPPEELPSPSASSLGPILPP---LPGDDSPTTLCSFFPRMSNLRLANPAGGRPGSKGEPGRAADDG-EGIVGAAMPDSG--------PLPLL------------QDMNKLSGGGGRRTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEE---EPPDHQYYNDFPGKEPPLGGVVDMRLREGAAPGAARPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPGRE--LFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z1Z9-1", "uniprot_id": "A0A8M6Z1Z9_DANRE", "id": "A0A8M6Z1Z9-1", "name": "SHC-transforming protein 1", "aln": "MELVP-KTKYTPFRSDSFSSTDETASNPSLPSSAPLTPLTPPGIPPSLSSSSLTPILPPSSPRQAENSPTTLCSFFPRMGALRLGVSSTLLPGLKASSRPANVPGSQGGLGESSEDTGTVNSSPPRLLPLLSLTAPSPPPRPPQDMNRL-GGASRRARVEGGQLGGDEWTRHGSFVNKPTRGWLHSDIVVSTSGVSYTVRYMGCVEVLQSMRALDFNTRTQVTREAISVVCEAVPGAKGAQRRRKPSSRCLSSILGKSNLQFAGMTITLTVSTSSLNLMAIDCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECSEGLAQEVISTIGQAFELRFKQYLKNPPKVVTPHDRMAPFDGSAWEEEEEDLAPPPEVPYYNNFPGKQPPPGGLVDMRTRPG----------------HSTGPTLPYGQPSQND--IHKQPLPPLPVGVKDGGLFDDPSYVNVD---KPR------LPASAAANGNAHRDAFDMKPFDAALVVSG-AVALPLAEQLQNEPWFHGPLSRRQAERLLTKDGDFLVRESGTTPGQYVLTGQQGGQPKHLLLVDPEGVVRTKDHRFESVSHLISYHMDNRLPIISAGSEVCLQQPVDRKA-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3C8-1", "uniprot_id": "Q9V3C8_DROME", "id": "Q9V3C8-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MPKNGDAGNRSGS--GTTSDGCIYPDDVIMGVGVAFNVRYTGCVEVKTSMKSLDFETRTQLARECINRVCEAA-GLKSAGKRRLTN-----FISDRPSMQHAGTNIIINVSSRALSLSNVETGEVIANHNMPRISFASGGDNDTLDFLAYIAKNEDEWRACYVLECAGGQSEDLIVTIGKAFALRFNALSR----LNDPSADCN-INQSCKENVKE---------YYNDLPNKLPP---------------------------------EVPEPQQQQVQQPLHPHAPRVAQLNLKK--PRDRLSSNLIDLN---------SPPPDQTTNKLGHFDPLQATTAANSVLPSVRDVFDGPQCPLTAEVWFHAGISRPISERLLQQDGDFLVRESQGKRGQYVLTGLEGKTPKHLLLIDPEGVVRTKDRIFDSISHLINYHWAHALPIISEDSELVLRNPVRRPQQDQAASPITSASS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*: .* ** ...: * ::.: : **:: *** ***** **::***:****::**.*. ****. * *.* :** . * .:..::.** * :.**: :*.* : ::****:* ******** ** :::**:**: : ***::***. * ::::* ***:** ***: : : * :: *. :: :* ***::*.* ** :* * : :: : :. * * :: *.. : * . * :: .. :: . * * ***. :** :* ** :******** . ******* :. ******:**********: *:*:****.** : ***** .**: *::** * ", "identical_positions": 156, "similar_positions": 104, "identity": "24.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2542", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O75362-1", "uniprot_id": "ZN217_HUMAN", "id": "O75362-1", "name": "Zinc finger protein 217", "aln": "MQSKVTGNMPTQSLLMYMDGPEVIGSSLGSPMEMEDALSMKGTAVVPFRATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEKNCKE-NEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVR--CIPQLDPFTTFQAWQLATKGKVAICQ-EVKESGQEGSTDNDDSSSEKE------LG---------ETNKGSCAGLSQEKEKCKHSHGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLD---KNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEKQT-DVAAEVKNDGKNQDTEDALLTADSAQTKNLKRFFDGAKDVTGSPPAKQLKEMPSVFQNVLGSAVLSPAH-KDTQDFHKNAADDSADKVNKNPTPAYLDLLKKRSAVETQANNLICRTKADVTPPPDGSTTHNLEVSPKEKQTETAADCRYRPSVDCHEKPLNLSVGALHNCPAISLSKSLIPSITCPFCTFKTFYPEVLMMHQRLEHKYNPDVHKNCRNKSLLRSRRTGCPPALLGKDVPPLSSFCKPKPKSAFPAQSKSLPSAKGKQSPPGPGKAPLTSGIDSSTLAPSNLKSHRPQQNVGVQGAATRQQQSEMFPKTSVSPAPDKTKRPETKLKPLPVAPSQPTLGSSNINGSIDYPAKNDSPWAPPGRDYFCNRSASNTAAEFGEPLPKRLKSSVVALDVDQPGANYRRGYDLPKYHMVRGITSLLPQDCVYPSQALPPKPRFLSSSEVDSPNVLTVQKPYGGSGPLYTCVPAG-SPASSSTLEGKRPVSYQHLSNSMAQKRNYENFIGNAHYRPNDKKT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LVZ2-1", "uniprot_id": "A0ABK0LVZ2_RAT", "id": "A0ABK0LVZ2-1", "name": "", "aln": "--------MPTQSLLVYMDGPEVLGSSLGTQMEVDDAVPMKGPAVVPFRAAQEKSLATAEGHMPLDCMFCSQVFSHAEDLNQHVLLQHRPTLCEPAVLRVEAEYLSPLDKGQVPTEPPKEKSSKEMEELSCDVCGQTFPVAFDVESHMKKHKDSFTYGCSMCGRRFKEPWFLKNHMRTHNGKSGTRSKLQQGTES-PVTINDVVQAHAPGNISTPYKICMVCGFLFPNKQSLIEHSKVHAKETVPSASSTAPDGHQEEPTSPREELLQFLNLRPRSTAESTVKPMT--SIPQLDPFTTYQAWQLATKGKVAVAQEEVKESGQEGSTDNDDSCSEKEELGEIWVGGKVEGSGKSKTNRSSCSGLSQDKDKSRHGNSEVPSGDADSKLPGSKEKPTHCSECSKAFRTYHQLVLHSRVHRKDRRADAPSPTMAGDARQPGTCSPELRTTLEESGAGDR-EGGSEDGSEDGLPEGLHLD---KNDDGGKAKPLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKDKQLGDAPAESKSEGRSQEPQDMLLTADSAQTKNLKRFLDGAKDVKGSPPAKLLKEMPSVFQSVLGSTVLSPAHNKDTQDFHKNAADG-AEKVRKSPAPAYLDMPRKK-TGDPRASSPACKLEG-VGPLAR-------EAGHGEK-MDREADYRHKPGADCQDRPLNLSLGALHACPAISLSKCLIPSIACPFCTFKTFYPEVLMMHQRLEHRYNPDTHKNCSSKSVLRNRRTGCPPALLGKDVPPLSGLHKPKAKPAFSSQAKALHPEKVRQGTSGPGKAPQTSGPDNSTLAPSNLKSHRSQPSAGGP-SATRQQQSELFPKGGVPAAMDKAKRPEPKLKAPPAPPAQSPLSSGNGNG------SAECPWGQQGRDYYCQRNAGSATSEYSEPHPKRLKSPVVSLDTEHPGPNGRRGFELPKYHVVRSITSLLPPEYVCSPPVLPPKARFLSPGEVESPSVLTVQKPYGASGPLYTCGPVG-HAGASPSLEGLTLCSLGWLQLNMRLLSHLSSGVKGVEQRWCPFLV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E7EZ61-1", "uniprot_id": "E7EZ61_DANRE", "id": "E7EZ61-1", "name": "", "aln": "--------MPTHPLIPYVESPDGLGHDILS--HSSASMPGTGSSMTPHASLVEKPGILAESSLPLDCMFCEETFLHQEDLGPHLLSQHPTTFHGPAVLRVEAEFLTPGDRARSKTCPAVEK----NEELSCAVCGQAIKDATELETHMRKHKDSFTYCCSICGRRFKEPWFLKNHMRTHG---KTGSKSKNHELEIPATVNDVIQDQPPSPVVTSYKMCMVCGFFFHNKEALAEHSKVHNRDAEADENISTHDQPAEELPVSQHAFLQNLQLHPSVAREAEPKHPTGRWISQLDPFNTYQAWQLATRGKIAAGPNLAKELNADSNSDNEDSGSEKEELG---------------AIWASGDKPARRGLRSELKPSDTPSPSPEQKGLIRKDKPTNCEECGKIFRTYHQLVLHSRIHKKER-GGAESPTTPVDGRAQSVGS-------CSSSSLDRADEYSEDGSEEGVPVDAFNPDKLEDGQGKMKLKILAPRKCNYCGKTFRSNYYLNIHLRTHTGEKPYKCEYCDYAAAQKTSLRYHLDRRHKDKPFTEIPN----------------IPATPSARNIIKAIEPPKNVDNKQASKPPKQWLAPKP--LPASVKHELGTSQVIKSTSPSIQVKQEFVSSPVATPYTPLSEDNKKYPLPAN-------------------------------------LKMEEKEASEAPLNLSLKVSLSISATSVPRNLLLTNTCTSCSYETLYPEVLLMHKKLIHKQNLDIKKNGYRGPQKLKRYTGCPPALEGKDVAPLAHINRRHPRRTKSP---------LRQPPEKLQKPPQMSKVSPVKERWRDQHRGRELDATNLLPRKPEQESSRKFN------VPSVIDRELPKQKPVLDHEMNQRMGKNGMVWP-----------TDPARLCLSDRFRNLTQMEVGEPSSKRQKS---FEPLHTASGRLGEDFNRLVPSGRNAKTSLQTHSPLASIKVTPTASSNSMQPDWNVMNMLRTYTPNNLASLYHPIAPSSSHGVMSSPVSGSRSLIFPQYSTSMSQRRIQSSPLNNERCGGPSDKSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:.*: *::.*: :* .: : . . ::. .*.::.*. : ** *. :*******.:.* * ***. *:* ** .*: *********:*:* *:.: * *. ** :*:** ****:: * ::* **:.******* *.:******************. : ** :: . *.*:*:*:* :.. : :.**:******:* **::* ** *** :.: . . : * . .:. :** ::*:* *: * *.*****.*:*******:**:* .** . :..:**:** **** : .* :: :.. .:.** ..: * *:***:*.**.* ************:*:*:* ..* *** . *.* .. * ...: ** : ******:*:* . . ::.:* : :.*:*.**** ***********************:*:*************:*:**:* : . . :..::*: : :: .*:* .. .:* *: : * ::* .:. . . : : : * . :..* : ... *. :. : *****: . .* *:.: *: : :*. *:::*:*****:**::* *: * * :** . .* ******* ****.**: : : :.: : .. :* . *.* * . . : : * .. ..*:.*. * . . .* .* *. : :.... .* .:* . : * .** .** ** . .. . ..:: .. *** . . : . . *. . : : .:* . .* . :. :. * . *..:.* . .* .. : . . ", "identical_positions": 310, "similar_positions": 288, "identity": "28.86%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2547", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AKA1-1", "uniprot_id": "A0A8I6AKA1_RAT", "id": "A0A8I6AKA1-1", "name": "", "aln": "MKFPCSACSLVSLGMSGEHHHMDRDSRNMSLALEIMESFACVLEKPGRTFLCFGKFVVPISLTSSGAKTPGARALGLQRAEMTMTANKNSSITHGAGGTKAPRETLSRSQSVSPPPVLYPPRSPIYP-LSDSE--TSACRYPSHSKSQVLLKDRHSRNPSPLG-QDPSPDTSPPICTLKATSFSYLDRTPSLRR-----REDQRESVQGAVQDVEG--VAACLPLAQSTPFLG--SGPRSVLLSCTGTRAHNLGIREKISAWEGRREASPRMNLCGEKREGPGSERSVSEGCPSVGCPSVVPSPCSSEKTFDFKGLRRMSRTLSECSYPETEEESEALPVRDSLYRLEKRPSRTEPS-ALLRGHGIRKESSAVLSRIQKIEQALKEQPGCGLPQLPSSCYSVDHGRRKTGTLGTSEEPAGTASVSSSSRAGGATGVAREAGPPLDREGSGSMKSETPGN-SSSPQLLPSKSSPDPAVNPVPKPKRTFEYEADKNPKPK-PSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDIRGHRKSQNRKSFEFEDASSLQSLYPSSPTENGTESQPKFGSKSTLEENAYEDIVGGLPKENPYEDVDLKNRRAGRKSQQLSENSLDSLHRMWSPQDRKYNNPPMQLSLKPSSQSLRSGNWSERKSHRLPRLPKRHSHDDMMLLAQLSLPSSPSSLNEDSLSTTSELLSSRRARRIPKLVQRINSIYNAKRGKKRLKKLSLSSLETASLRDENSESESDSDDRFKAHTQRLVHIQSMLKRAPSYRTLELELLEWQERELFEYFVVVSLKKKPSRNTYLPEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLLPNGKGPRLPEVYCVISRLGCFGLFSKVLDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIFASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELISQDSDSDSDDECNT-LNGLVSEVFIRFFVETVGHYSLFLTHSEKGERAFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGLFEQRVEQYLEELPDTEQSGMNKFLRGLGNKMKFLHKKN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q924W7-1", "uniprot_id": "DEN2B_MOUSE", "id": "Q924W7-1", "name": "DENN domain-containing protein 2B", "aln": "---------------------------------------------------------------------------------MTMTANKNSSITHGTGGTKAPRETLSRSQSVSPPPVLYPPRSPIYP-LSDSE--TSACRYPSHSKSQVLLKDRHSRNPSLLG-QDPSPETSPPICTLKATSFSYLDRTPSLRK-----REDQKETVQGAVQDVEG--VAACLPLAQSTPFLG--AGSRSVLLSCTGTRAHSLGIREKISAWEGRREASPRMSLCGEKREGPGSEWSVSEGCPSVGCPSVVPSPCSSEKTFDFKGLRRMSRTFSECSYPETEEEAEALPGRDSLYRLEKRPGRTEPS-ALLRGHGIRKESSAVLSRIQKIEQALKEQPGRGLPQLPSSCYSVDQGRRKTGTLGTLEEPTGTASVSPSSRAGGVAGVAGEAGPPLDREGSASMKSETPGN-SSSPQLLPPKSSPDPAVNPVPKPKRTFEYEADKNPKTK-PSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDMRGHRKSQNRKSFEFEDASSLQSLYPSSPTENGTESQPKFGSKSTLEENAYEDIVGGLPKENPYEDVDLKNRRAGRKSQQLSENSLDSLHRMWSPQDRKYNHPPMQLSLKSNSQSLRSGNWSERKSHRLPRLPKRHSHDDMMLLAQLSLPSSPSSLNEDSLSTTSELLSSRRSRRIPKLVQRINSIYNAKRGKKRLKKLSMSSLETASLRDENSESESDSDDRFKAHTQRLVHIQSMLKRAPSYRTLELELLEWQERELFEYFVVVSLKKKPSRNTYLPEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLLPSGKGPRLPEVYCVISRLGCFGLFSKVLDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIFASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKSELISQDSDSDSDDECNT-LNGLVSEVFIRFFVETVGHYSLFLTHSEKGERAFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGLFEQRVEQYLEELPDTEQSGMNKFLRGLGNKMKFLHKKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78524-1", "uniprot_id": "DEN2B_HUMAN", "id": "P78524-1", "name": "DENN domain-containing protein 2B", "aln": "---------------------------------------------------------------------------------MTMTANKNSSITHGAGGTKAPRGTLSRSQSVSPPPVLSPPRSPIYP-LSDSE--TSACRYPSHSSSRVLLKDRHPPAPSPQNPQDPSPDTSPPTCPFKTASFGYLDRSPSACK-----RDAQKESVQGAAQDVAG--VAACLPLAQSTPFPGPAAGPRGVLLTRTGTRAHSLGIREKISAWEGRREASPRMSMCGEKREGSGSEWAASEGCPSLGCPSVVPSPCSSEKTFDFKGLRRMSRTFSECSYPETEEEGEALPVRDSFYRLEKRLGRSEPS-AFLRGHGSRKESSAVLSRIQKIEQVLKEQPGRGLPQLPSSCYSVDRGKRKTGTLGSLEEPAGGASVSAGSRAVGVAGVAGEAGPPPEREGSGSTKPGTPGN-SPSSQRLPSKSSLDPAVNPVPKPKRTFEYEADKNPKSK-PSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDMRGHRKSQSRKSFEFEDASSLQSLYPSSPTENGTENQPKFGSKSTLEENAYEDIVGDLPKENPYEDVDLKSRRAGRKSQQLSENSLDSLHRMWSPQDRKYNSPPTQLSLKPNSQSLRSGNWSERKSHRLPRLPKRHSHDDMLLLAQLSLPSSPSSLNEDSLSTTSELLSSRRARRIPKLVQRINSIYNAKRGKKRLKKLSMSSIETASLRDENSESESDSDDRFKAHTQRLVHIQSMLKRAPSYRTLELELLEWQERELFEYFVVVSLKKKPSRNTYLPEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLLPSGKGPRLPEVYCVISRLGCFGLFSKVLDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIFASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELISQDSDSDSDDECNT-LNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGLFEQRVEQYLEELPDTEQSGMNKFLRGLGNKMKFLHKKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TY47-1", "uniprot_id": "A0AB32TY47_DANRE", "id": "A0AB32TY47-1", "name": "", "aln": "-----------------------------------------------------------------------------------MTANKSSKTAPRAGAAKGSQENSDRCQSVSPPPILTTGKEPVSSYLSGSEDTSQQGKYGKADAKLWTQKNWSCKTASLRSGASLSTDFECQSRLTKSRSISCLDKRLTIHKPPSGDRQDQKENQLQQTPPIGDGLNTGLLSLSTTSVGPSKLGHKRTFSLSHTGTCTSSIAIRKKISQWEGRKEALSRMSLCLEKRPGGGSE----------GCPSLLSSPCS-ETTFDFKGVRRMSTAFSECSYPETEED-EHTSDREAPIRFQKRPSKTESSGIFLRTFSARKETSAVLSRIQKIEQALKESPTSSPPQYLSNCYGLDKSRQKSFTISGTEDLDSTCGSKRSSICS--VATEPDVSPGSDRLFKLKQRFSISSTRSESPELPSAQDSPGITVNPLPKPKRTFEYDANRNHKSLLPGNGLPPS--TESPPPLPSTPAPAIVTNSKTDESKLKKTQDRESCESEDAVSLP----SSPTENGTVNHSRPSSKSTLEENAYEDIVE---KENPYEDVDPVRRCLARNSRLLPERSRDSLNRMWTSQERKSITPP-QLPSKPSSQSLRLPGPADRKSQRPSRLSKRHSHDDMLLLPQLGMPSSPCGLLDDSLNPSTDTLASHRQKRVPKVVLRINSIYCTKRGKKRLKKLSLSNIETASLRDDNSESESDSDDRFKAHTQRLLKLQSILRRAPSYRTLELQLIEWQERELFEYFVVVSLKKKPTKNSYAPEVTYQFPKLERLTKQMREAEQRLKAIPQFCFPDAKDWSPVSEYNSETFSFMLTGEDGSRRFGYCRRLLPSGKGPRLPEVYCVISRLGCFNLFSKILDEVERRRGISAALVYPFMRSVMESPFPAPGKTIKVKTFLPGAGNEVIELRRPMDSRLEHVDFESLFNCLSVRQVVRVFASLLLERRVIFVADKLSTLSSCVHAVVALLYPFSWQHTFIPVLPTSMVDIVCCPTPFLVGILSSSLPKLKELPVEEALMVDLGTDRFIRQMDDEASLLPRKLQAALEQSLEQRNDIINQDSDSESDEECSTSLNSVVSEAFIRFFLETIGHYSLFLTQGERGERIFQREPFRKSVASKSIRRFLGVFMESQMFAGFIQDREMRKCRAKGLFEQRVEQYLEELPDTEQSGVNKFLKGLGNKMKFLHKKN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****.*. : :*.:*..: . .*.*******:* . :.*: . **.** :. :* . . . *: .* . . *.: . *: *:. **: : : *: *:*. . : . :. *.*: :: . . * . *: *** : .:.**:*** ****:** .**.:* *** * *** ****::.**** *.******:**** ::**********: * . *:: *::** .::*.* :** .. ***:************.***.* . ** *.**.:*:.::*: *:. *: . .. . .* . ... :..* :* . . : ... * *.: ..:.* . :***:*********:*::* *. *.****** . :**********.:. ..*.* :*:*.*:* * *** ** ******** .:.: .************** ********* * .*:*: *.*.* ***:***:.*:** ** **. *..***** . ::***:* .**.********:**.**.:****..* :***..::: *:*:* :*:**:* ****** :***********:*.:*******:*******************:::**:*:**********:*:********************::*:* ***:******:* ********:**************** *****.*************************.*******************.****:*********************:*************************:****************.**.******::*:*********************** *********************:**:************:*******************:**:********** :************:**::.::*.*****:**:**.* **.:***.*****:**:********:.*:*** ****.************** ****************:***************************:****:*************", "identical_positions": 720, "similar_positions": 240, "identity": "58.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2552", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D8F3-1", "uniprot_id": "S52A2_MOUSE", "id": "Q9D8F3-1", "name": "Solute carrier family 52, riboflavin transporter, member 2", "aln": "-------MAAPPLGRLVLTHLLVALFG----------MGSWAAVNG------IWVELPVVVKELPEGWS-LPSYLSVLVALGNLGLLLVTLWRRLARGKGEQVPIRVVQGLGIVGTGLLASLWNHVAPVAG---------KPYSVAFLTLAFVLALACCASN-----VTFLPFLSHLPPPFLR------SFFLGQG----------------------LSALLPCVLALG--QGVGRLECLHVPANRTTGPPIEVSPINFPERFSATTFFWVLTALLGTSAAAFQGLLLLLPSPTSEPT--TGTGLRVETPGTEEEEEEEEASPLQEPP-----------------GQVAGIVSSPD----PKAHQLFSSRSACLLG----LLAITNALTNGVLPAVQSFSCLPYG--------------------RLAYHLAVVLGSCANP------------LACFLAMA--VLCRSLAG-------------------------------------------------LCGLSLLG---------------------MLLGSYLMTLAALSPCPPLVGTS------------------------------AGVVLVVLSWVLCAGTFS-------------------------------YIKVAISSMLHSGGRPALLAAGVAIQVG--SLLGAVAMFPPTSIYRVFRSGKD----CVDQCGL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HAB3-1", "uniprot_id": "S52A2_HUMAN", "id": "Q9HAB3-1", "name": "Solute carrier family 52, riboflavin transporter, member 2", "aln": "-------MAAPTPARPVLTHLLVALFG----------MGSWAAVNG------IWVELPVVVKELPEGWS-LPSYVSVLVALGNLGLLVVTLWRRLAPGKDEQVPIRVVQVLGMVGTALLASLWHHVAPVAG---------QLHSVAFLALAFVLALACCASN-----VTFLPFLSHLPPRFLR------SFFLGQG----------------------LSALLPCVLALV--QGVGRLECPPAPINGTPGP-----PLDFLERFPASTFFWALTALLVASAAAFQGLLLLLPPPPSVPTGELGSGLQVGAPGAEEEVEE--SSPLQEPP-----------------SQAAGTTPGPD----PKAYQLLSARSACLLG----LLAATNALTNGVLPAVQSFSCLPYG--------------------RLAYHLAVVLGSAANP------------LACFLAMG--VLCRSLAG-------------------------------------------------LGGLSLLG---------------------VFCGGYLMALAVLSPCPPLVGTS------------------------------AGVVLVVLSWVLCLGVFS-------------------------------YVKVAASSLLHGGGRPALLAAGVAIQVG--SLLGAVAMFPPTSIYHVFHSRKD----CADPCDS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HXG3-1", "uniprot_id": "A0AC58HXG3_DANRE", "id": "A0AC58HXG3-1", "name": "", "aln": "MEDLQDFGSSSASAKTIAAELKDDFYSKLVDDFLGAHYGDLLELDGKNWKNRMLVQIGLLREEQDVSWVDLIQWLQKIIPMFKSADFRSLIERNTTTALSLTGDARENFFESDVNFEFVGPICDSIGIGRRDLLEMSDLSDRAKLTALTNGLVLELTNFISREKLDPVVLVSWIRNFEPLFCSDGKIQRAYKLLRGNLRIFRMQYRNNQRSRKRSRGLLEEFLQSPFDLSPEADADDVEYRRVAMNKAHLKRKRRMYKHTTAMKDEDEHFNISQIDVTVKTHEPMRHEPMQHEPKQHEPKQMPHAMFVKKELGSQTHQSQNQNPEEDTKTDTGDNVTLLDIAVLSWQKMAGIYGGPNEAAKVVSLDLLQNHFNAMLKNDDDLRSLDEKVKASTHPIVPPLDFLRYISQFLFELIDVTEQQMISFEKDIVFTTAEKLGRDKHPRFQTFVNFEESAVTRYINMASEMLCPSDVTNPNYRRLWLAFCLERKIPSSLPIYRSNRVINYFEAAAGLIHHHEEVALFVSDLQLLNNNSSILLDSINADANDKTLQTLVCVVAIIYLKVLGPFWQLLKSDGEYPFFSRYIFCLYDKLLECSLDTSRLLQPENFVNVFLQAPIQEGTFAGVFRFCRDNADNQYGTLLKTCLQKMMKALAAVMEDNLKDFLPGGKHCKDLPGDIAVQMANCTFLQLMGEYPFGHTYPYKKKRPDKAVNQTEGCASKEAQQEPASQKVSDTPTSPAASLSPQKTIQMQQWISKPYSIIEGANLKKMKASRLKQRAQGHIYRKMIIGTISKYGGPCKSKQDVERLLQKLEGASLNHKREVIRSELNYQKSISGSRDKKLSNIGFSLNDMVSTLKDVLPNDKSIVSPSTENVLDHSTDPNSSIASRP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.. .: : :.* ::. *. ::* : *:: :: :* .* * .::. ::.: : . : : *. : . . * . *. ::..: . :. . .:: *: .:** *: *. *.::.:: :: * * :: * :* *. :* . : * ... :* .. * : . .* : ..: : * . . .: * .: :. .* ::. : ** .*: : :*:. : .:* * : : :. .. * * .:. * * :.: * ** :* :: :: *. :** * . : .*.**. :. :: * .*.* *: :. ..* *.*. : *.*: :: ..:* .* : *...:*:*:. ::* :. :* * :. * .: * ", "identical_positions": 69, "similar_positions": 171, "identity": "7.8%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2555", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96DM1-1", "uniprot_id": "PGBD4_HUMAN", "id": "Q96DM1-1", "name": "PiggyBac transposable element-derived protein 4", "aln": "--------------MSNPRKRSIPMRDSNTGLEQLLAEDSFDESDFSEIDDSD----------------------NFSDSALEADKIRPLSHLESDGKSSTSSDSGRSMKWSARAMIPRQRYDFTG--------------------------TPGRKVDVSDITDPLQYFELFFT--EELVSKITRETNAQAALLASKPPGPKGFSRMDKWKDTDNDELKVFFAVMLLQGIVQKPELEMFWSTRPLLDTPYLRQIMTGERFLLLFRCLHFVNNSSISAGQSK----AQISLQKIKPVFDFLVNKFSTVYTPNRNIAVDESLMLFKGPLAMKQYLPTKRVRFGLKLYVLCES---QSGYVWNALVHTGPGMNLKDSADGLKSSRIVLTLVNDLLGQGYCVFLDNFNISPMLFRELHQNRTDAVGTARLNRK-QIPNDLKKRIAKGTTVARFCGELMALKWCDGKEVTMLSTFHNDTVIEVNNRNGKKTK---------RPRVIVDYNENMGAVDSADQMLTSYPSERKRHKVWYKKFFHHLLHITVLNSYILFKKDNPEHTMSHIN----FRLALIERMLEKHHKPGQQHLRGRPCSDDVTPLRLSGRHFPKSIPATSGKQNPTGR-----CKICCSQYDKDGKKIRKETRYFCAECDVP--LCVVP---CFEIYHTKKNY----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13ABV5-1", "uniprot_id": "A0AB13ABV5_DANRE", "id": "A0AB13ABV5-1", "name": "", "aln": "-----------MDETNENRTDECVEDSSEDEDETLASEESSDESAASSADSGEEMFLEAMDPVLNGFIDDSDEDWSPEVTPLKKKRKGPSSVSPSPAKSRRTASPGSARSAKGRKGSVRRSLPFSCSILESKWKSVDEPDIEPPQLLFKPKRTPGPQLISTSSCSVLQYFQLFFS--KSVMQKIVDHSNIYASMHTNEKKKP--------WKNITIKDLKSFIAMVIYMGIVKCFNLTDYWKRTDFYSLPYPARIMSCRKFLSMCWALHLSNPKVDAENDKKKGTPQYDRLCKIKPLYQDIRDACKASFHPHQNISIDERMVASKARHGLIQYMKNKPTKWGYKLFVLADS---LCAYTWDFFIYEG--KVKTEQRKGISYDSVMALIDERVLGTGYKLFVDNFYTSPTLFRDLLSKKIGACGTIRANR----IGHSKTPAPRGNIRWFREDGLLFVEWKDKRDVLMCSTFHKAYNGDYIKRNVKGKGGVWTPQDFPVPAAVLDYNKHMGGVDVSDALIG-YYTVLHKTKKWYRSFFYHFVDIAVVNAFILHQQ------MAKSK----NQKAMTQKVFRETLVAELAGIRAGYPPAREAAIASTDNHLPKYIKGDS--TFGRRK-----CKLCT-----------HKTPITCVTCQVH--LCFVPKRDCYTKWHESGNSDSDTE-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHL1-1", "uniprot_id": "Q9VHL1_DROME", "id": "Q9VHL1-1", "name": "PiggyBac transposable element-derived protein domain-containing protein", "aln": "MSSSGRKRKQQLKPRQDDHRSPVKRRSVDIKSEPLDGYPALADYDLSTADIKP-----------------DLTELQLQLVAEQQAASNTIRLELEQQESDSDEDGYSELDYQAEDVFCQDDMDDYDPDWSSQ-------------------QTGSRLLFKFPIQQSGLKFGQRFQGPQHYFNQVLGNRSKFFSSLAQSCNLKGG---ELKSNPTTAEEMEIFMALSLLMCDLKLEHLSDYWSTNMFYGLVGFSGKIPLERYQQLLHCLNFDAPQLQAG----------RAKVKNSLLLDFINERMEEIYICGQQLVLNEPITLWKGALRYQDELPNKFRTNALLLHMLTEQSGLVVKILPEIVRKEDAPAWVRNSRQLVEHRNKIVLKLMEGYHGGRTVYTSKFYGSYGLAQELAKKSTYCTGLLDRNRYGNSKALVHQRLDSNSISTSYATSLMMAKWR--RRAKSLYCFSSDCLAIYSKEMAMQKTN-------AKPKLIQELEFQLRPGNDGRHHLIHYQAACKELKANIK-LTIFLLNILVYNAYLLYFANGQNARVGHLKSYSEFRVIIIKSLLREEVTNEPVTSIQKPETYERSKNKPVPEPRLKTILHEPMLIQQNGKPAKKNCRYCHKG------GMLQFSRYMCNTCPDKPGLCQEP---CFLLWHEQLKKVIRQTIGRSE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : . : * * . : : * * . . . : . . :* . . ... : * . : . * * : ..:: . . : :.. : .::: *:*: : :: .* :*. : . :. .:: : .*:: . : * . : : : : . : ::: ::* : *. : : .* . *.:* :. : . . :. . :. : * :: .:* * * ::* .: . * ** : .. *: :* : . * . :. . * : : : :: : . : * : :. * : : .::.* * *:::*. :.: : : : : ::.: . : . * * . : *: * : : * * ** * *: :* . : ", "identical_positions": 48, "similar_positions": 156, "identity": "6.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2575", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O94906-1", "uniprot_id": "PRP6_HUMAN", "id": "O94906-1", "name": "Pre-mRNA-processing factor 6", "aln": "----------------------------------------MNKKKKPFLGMPAPLGYVPGLGRGATGFTTRSDIGPARDANDPVDDRHAPPGKRTVGDQMKKNQAADDDDEDLNDTNYDEFNGYAGSLFSSGPYEKDDEEADAIYAALDKRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGDARNKRQRNPRYEKLTPVPDSFFAKHLQTGENHTSVDPRQTQFGGLNTPYPGGLNTPYPGGMTPGLMTPGTGELDMRKIGQARNTLMDMRLSQVSDSVSGQTVVDPKGYLTDLNSMIPTHGGDINDIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEAARLQPGDTAKAVVAQAVRHLPQSVRIYIRAAELETDIRAKKRVLRKALEHVPNSVRLWKAAVELEEPEDARIMLSRAVECCPTSVELWLALARLETYENARKVLNKARENIPTDRHIWITAAKLEEANGNTQMVEKIIDRAITSLRANGVEINREQWIQDAEECDRAGSVATCQAVMRAVIGIGIEEEDRKHTWMEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGILWSEAIFLEARPQRRTKSVDALKKCEHDPHVLLAVAKLFWSQRKITKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKRCESAEPRHGELWCAVSKDIANWQKKIGDILRLVAGRIKNTF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8PWG5-1", "uniprot_id": "A0A2R8PWG5_DANRE", "id": "A0A2R8PWG5-1", "name": "Pre-mRNA-processing factor 6", "aln": "MASSAAKQPPKNASKAPSGGAGGAAAGAAAMPLASPLMGGLNKKKKPFLGMPAPLGYVPGLGRGATGFTTRSDIGPARDANDPVDDRHAPPGKRTVGDQMKKSQ--DDDDEDLNDTNYDEFNGYAGSLFSSGPYEKDDEEADAIYAALDKRMDERRKERRELREKEEIEKYRMERPKIQQQFSDLKRKLSEVTEDEWLSIPEVGDARNKRQRNPRYEKLTPVPDSFFAKHLQTGENHTSVDPLQGQFGGLNTPFPGGLNTPYPGGMTP-----DAGELDMRKIGQARNTLMDMRLSQVSDSVSGQTVVDPKGYLTDLNSMIPTYGGDISDIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEAARLQPGDTAKAVVAQAVRHLPQSVRIYIRAAELETDIRAKKRVLRKALENVSKSVRLWKTAVELEEPEDARIMLSRAVECCPTSVELWLALARLETYENARRVLNKARENIPTDRHIWITAAKLEEANGNTQMVEKIIDRAITSLRANGVEINREQWIQDAEECDKAGSVVTCQSVIRAVIGIGIEEEDCKHTWMEDADSCVSHGALECARAIYAHALQVFPSKKSVWLRAAYFEKNNGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENNEYERARRLLAKARSSAPTARVFMKSVRLEWVLGNIEAAHELCTEALKHYEDFPKLWMMRGQIEEQSESIDRAREAYNQGLKKCPHSMSLWLLLSRLEEKVGQLTRARAILEKARLKNPQSPELWLESVRLEYRAGLKNIANTLMAKALQECPNSGILWSEAVFLEARPQRKTKSVDALKKCEHDPHVLLAVAKLFWSERKITKAREWFLRTVKIEPDLGDAWGFFYKFELQHGTEEQQHEVKKRCENAEPRHGELWCAESKHILNWQKNIGEILVLVASKIKNSF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*************************************************************.* ******************************************************* ***************************:****:*********************************************** * ********:************** .:************************************************:****.*************************************************************************************************************:*.:******:*****************************************:***************************************************************:****.***:*:************ ************:*.**********:*********************:********************************************************************:**************************:**** .**.**::** ***:***********:******.* :::*************** .***********:************:*****:.* ***************************************:********:**************************:********** *****:.******.***************.**:****.*********** **.* ****:**:** ***.:***:*", "identical_positions": 867, "similar_positions": 54, "identity": "88.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2579", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14974-1", "uniprot_id": "IMB1_HUMAN", "id": "Q14974-1", "name": "Importin subunit beta-1", "aln": "MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAEIPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDDDDWNPCKAAGVCLMLLATCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKDPSVVVRDTAAWTVGRICELLPEAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAEAAYEAADVADDQEEPATYCLSSSFELIVQKLLETTDRPDGHQNNLRSSAYESLMEIVKNSAKDCYPAVQKTTLVIMERLQQVLQMESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQDALQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLGGEFLKYMEAFKPFLGIGLKNYAEYQVCLAAVGLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDIALAIGGEFKKYLEVVLNTLQQASQAQVDKSDYDMVDYLNELRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIGDLCTAFGKDVLKLVEARPMIHELLTEGRRSKTNKAKTLATWATKELRKLKNQA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IMZ8-1", "uniprot_id": "A0A0R4IMZ8_DANRE", "id": "A0A0R4IMZ8-1", "name": "", "aln": "MELITILEKTVSPDRNELEAAQKFLEQAAIENLPTFLVELSKVLANPGNTQVARVAAGLQVKNSLTSKDPEVKSQYQQRWLAIDTSARREIKNYVLQTLGTETYRPSSASQCVAGIACAEIPVNQWPELIPQLVANVTDPSSTEHMKESTLEAIGYICQDIDPEHLQDSANQILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKETERHFIMQVVCEATQCPDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEATEASEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDDDDWNPCKAAGVCLMLLATCCEDDVVPHVLPFIKEHIKHPDWRYRDASVMAFGSILEGPELNQLKPLVIQAMPTLIELMKDPSVVVRDTTAWTLGRICDLLPEAAINEVYLSPLLQCLIEGLGAEPRVASNVCWAFSSLAEAAYEATDVADDQEEPSTYCLSSSFELIVQKLLETTDRPDGHQNNLRSAAYEALMEIVKNSAKDCYPAVQKTTLVIMERLQQVLQMESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQDALQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLGSDFLKYMDAFKPFLIIGLKNYAEYQVCLAAVGLVCDLCRALMANILPYCDEIMQLLLENLGNENVHRSVKPQILSVFGDIALAIGGEFKKYLDIVLDTLQQASQAQVDKTDYDMVDYLNELREGCLEAYTGIIQGLKGDQENVHPDVMLVQPRVEFILSFIHHIAEDEDRSDGVVANAVGLIGDLCTTFGKDVMKLVEVRPQINDLLTEGRRSKTSKTKTLATWAAKELRKLKSQA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************** **********:**:***********:*******:**********:*********::*:**********:.****:***********************************************:*.***********************:***.:*:****************************************:************************************************************************************:**:*************************************************************:*************:********:*****.****** .***************************:***:****:********:***:**********.***********************:*********:*******************************:***:*************************************************************************************************************.:*****:****** ******************* ****** :**:*:***:****************************************::**:************:*************.********:****************************.*** ***::***** *.********:*****:****.** *::**********.*:*******:*******.**", "identical_positions": 807, "similar_positions": 61, "identity": "92.12%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2581", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O96028-1", "uniprot_id": "NSD2_HUMAN", "id": "O96028-1", "name": "Histone-lysine N-methyltransferase NSD2", "aln": "MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQE--MKGIG-TPPNTTPIKNG--SPEIKLKITKTYMN--GKP-LFESSICGDSAADVSQ----------SEENGQKPENKARRNRKRSIKYDSLLEQGLVEAA--LVSKISS-----------------------------PSDKKIPAKKESCPNTGRDK-----------------DHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNP------QVAKEAGIAAESLG----EMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAE-----TLESHPDIGKSTPQK--------TAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASGEEIEELLRSQWSLLSEKQRAR-YNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAEAEDTPR--KRLRTDKHSLRKRDTITDKTAR-TSSYKAMEAASSLKSQAAT----KNLSDACKPLKKRNRASTAASSALG----FSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLCEKPGS-LLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BVE8-1", "uniprot_id": "NSD2_MOUSE", "id": "Q8BVE8-1", "name": "Histone-lysine N-methyltransferase NSD2", "aln": "MEFSIRKSPLSVQKVVKCMKMKQTPEILGSANGKTQNCEVNHECSVFLSKAQLSNSLQEGVMQKFNGHDALPFLPAEKLKDLTSCVFNGEPGAHDTKLCFEAQE--VKGIG-TPPNTTPIKNG--SPEIKLKITKTYMN--GKP-LFESSICGDGAADVSQ----------SEENEQKSDNKTRRNRKRSIKYDSLLEQGLVEAA--LVSKISS-----------------------------PADKKIPVKKESCPNTGRDR-----------------DLLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHNHTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEEQFEKLCQESAKQAPTKAEKIKLLKPISGRLRAQWEMGIVQAEEAASMSIEERKAKFTFLYVGDQLHLNP------QVAKEAGIVTEPLG----EMVDSSGASEEAAVDPGSVREEDIPTKRRRRTKRSSSAE-----NQEGDPGTDKSTPPK--------MAEAEPKRGVGSPAGRKKSTGSAPRSRKGDSAAQFLVFCQKHRDEVVAEHPDASGEEIEELLGSQWSMLNEKQKAR-YNTKFSLMISAQSEEDSGNGNGKKRSHTKRADDPAEDVDVEDAPR--KRLRADKHSLRKRETITDKTAR-TSSYKAIEAASSLKSQAAT----KNLSDACKPLKKRNRASATASSALG----FNKSSSPSASLTEHEVSDSPGDEPSESPYESADETQTEASVSSKKSERGMAAKKEYVCQLCEKTGS-LLLCEGPCCGAFHLACLGLSRRPEGRFTCTECASGIHSCFVCKESKMEVKRCVVNQCGKFYHEACVKKYPLTVFESRGFRCPLHSCMSCHASNPSNPRPSKGKMMRCVRCPVAYHGGDACLAAGCSVIASNSIICTGHFTARKGKRHHTHVNVSWCFVCSKGGSLLCCEACPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFNEVKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGSDSECLNRMLMFECHPQVCPAGEYCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKYAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSASLSSEEKGKKAKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFRSTQDGQSYCCEHDLRADSSSSTKTEKPFPESLKSKGKRKKRRCWRRVTDGK--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B8JIA4-1", "uniprot_id": "B8JIA4_DANRE", "id": "B8JIA4-1", "name": "", "aln": "MTDSKGGSLPAMPEPKSPTSMKQLSDSPGGRNGLVDG-ITDPTMLMNKAATQLAATPQESVPQMIGSHGHN--HTHEHLKDLTSRLLNGDTEKIPKLCAAPAGQPLLKGVEPVSQHASPPRKTSVSPELTVKITKCVVNLGGKPNRYEVDYTEEKAEETDAPLRLPEGVLTSPTARRDRQKKKGMVRKRIPPYPILTHAASSDQSPLLHPTINSNDITIEPCGLPVESIEHTHGDMPTCVTAFPDEQPLSDCEETVDAQGVDETDDAQGENDVKESYTETQSNVHFSVGDVIWTKVSGYPWWPCMITTDPEFNMHFRSKVNSRTGLLYHVQYFGDTPERGYVFEKCIVTFSGKHQYQSLSRS--NQLPINISGRK--RAVPRKFRQKWEIGVSQAKEALGLLTEERLAKFSFVYEDGKAQLNPHMLQVLEEQRNQGLQEEPVQREPQELVSLTPPDSTHSSPTNSSTTSTIPSLFSNPIDSSTSSGKTALPRKARKPSVKTNRRKQRSSTIEWIVTEASSAKQMPLTESTVQCEVNTEHKKKGKTNAGKRPYRKKDLLCIDLDLQPKASQKKPRHIRQKFPAAPNSVKKRKIKAGVSICDTLNTVSTSAGLSEVKASAPSTKLWEKEDASSKGMKKVCKRSRESKQDVTLQPKKKSKLEKDFKKWKCPKAASSAPAAVPAPRGRRRKTDRDENRKRSKKASKEEPPPKAKRGRKRKEESGRQSFPASKKCRPSSYAEPERPDSPSDS--TDESHPSKKAERTPGAKKESVCLVCEQTGEDIVTCAGQCYGTYHLHCIGVERSAE-KILCTACSTGVHVCFTCKKSEGEVRRCCALHCGRFYHEACVRLSALTVFENRGFRCPLHTCLSCHYSGRAACKATKGKMMRCLRCPVAYHVGDLCVAAGSEMISSSAIVCTNHFRAKKGYSHHSHVNVSWCFICSKGGRLLCCESCPAAFHPDCLNIAMPDGSWFCNDCRSGKKPKYRDVIWVKLGNYRWWPAEIRHPKNIPTNIQHLRHEIGEFPVFFFGSKDYFWTHQGRVFPYMEGDRGSKYQQT-GIGKVFKNALLDAETRFKEIEMEREAKEAHENNKKPPPFKYIKVNKPCGRVQVYTADISEIPKCNCKPSTERPCSFESECLNRMLLYECHPQVCPAGERCQNQDFTKRLYPETKIIRTAGKGWGLISLRDIKKGEFVNEYVGELIDEEECRSRIRHAQENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETQKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGAPNCSGFLGDRPKN--GHTSEPKAKLQKKKPKRKRARNEGKK-SEDECFRCGDGGQLVLCDKKGCTKAYHLSCLDRTKRPFGRWDCPWHHCDVCGKNSAAFCQLCPNSFCKAHQEGALRSHPLTGQLCCQEHEDSDIRPQTETAQLPPPTKPRKYRRRAEAKTTSKAPLKKRPRKNAEV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * * :: . . .*** .: *. ** . . .: : : :**: : **.* * :..*. . ::****** ::**:. : : :**: .. :::* :: ***:.:**** :* *** :* . : * :.. * :. ::* *** * * . . : : * ..*.* * :: :. :*: * *. : :::.***::*:***********:::** :: : : * :.::. ****:***:***.::***.:*:*.*: *::.*.:. :* * : . * :.:. ::* :**:*: **:** .: *** ***:*:* ..: :*** : :: *: *.: *:.. : .. : . * . ** . . .:*: .*. .. : :**.. : : . . : . :.:**.: : : :*. : : :.:: . : .::. :. : * :: .:: . :: . *.. . * . .. **.. :. : ** * .*:.: : . ..* : ..:*. :**** : ..: :. :* : *: ::** ... . *..* *:. : . ... .* * ..:*. *: * .***:** **** ** :**:.*. :: * * * *::** *:*:.* .* :: *: *::*:* **.**:*: :*:** . :**:*******: .*****.********:*:*** *. : :.:*******:******* ** *:***..:*:*.:*:** ** *:** **:********:***** *****:************ ************:*** :::*:**************: ****:*.***:::****************:****.************:** . ***:****** :**:**.*::::***:*::*.::****:*:****** *:**:***************: *.**. :********::*********** **** **** *******:* ******:: ***:****************** :**::*:**************************************** ********************************************.***********. :** *.* ***.:*:**:.***: ******************:* **********. *****:*:*********** *::**:******** **:*: . *: * **: : .:: * * : :* . : :.. * ", "identical_positions": 641, "similar_positions": 378, "identity": "43.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2585", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99JX7-1", "uniprot_id": "NXF1_MOUSE", "id": "Q99JX7-1", "name": "Nuclear RNA export factor 1", "aln": "--MADEGKSYNEHDD-RVSFP-QRRKKGRGPFR---------------WKCGEGNRRSGRGGSGVQSSRFEEDDGDVAMND-PQDGPRVRYNPYTNRPNRRGD--------GWHDRDRIHITVRRDRAPAERGGAGTSQDGTTKNWFKITIPYGRKYDKTWLLSMIQSKCSVPFNPIEFHYENTRAHFFVEDATTASALKGVNHKIQDRENRRISIIINASAPPYTVQNELKPEQIEQLKLIMSKRYDGNQQALDLKGLRSDPDLVAQNIDVVLNRRSCMAATLRIIEENIPELLSLNLSSNRLYKLDDMSSIVQKAPNLKTLNLSGNELKTERELDKIKGLKLEELWLDRNPMCDNFGDQSSYISAIRERFPKLLRLDGHELPPPISFDVEA-PTMLPPCKGSYFGTENLKSLVLRFLQQYYVIYDSGDRQGLLYAYHDGACCSLSIPYNPQNPVRKNLAEYVKDSRNVKKLKEPTQRFRLLKHTRLNVVAFLNELPKTQHDVNAFVVDISAQTSTLLCFSVNGVFKEVDGKSRDSLRAFTRTFIAVPASNSGLCIVNDELFVRNASPEEIQRAFAMSAPTPSSSPVPTLSPEQQEMLQAFSTQSGMNLEWSQKCLQDNNWDYTRSAQAFTLLKAKGEIPEVAFMK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBU9-1", "uniprot_id": "NXF1_HUMAN", "id": "Q9UBU9-1", "name": "Nuclear RNA export factor 1", "aln": "--MADEGKSYSEHDDERVNFP-QRKKKGRGPFR---------------WKYGEGNRRSGRGGSGIRSSRLEEDDGDVAMSD-AQDGPRVRYNPYTTRPNRRGD--------TWHDRDRIHVTVRRDRAPPERGGAGTSQDGTSKNWFKITIPYGRKYDKAWLLSMIQSKCSVPFTPIEFHYENTRAQFFVEDASTASALKAVNYKILDRENRRISIIINSSAPPHTILNELKPEQVEQLKLIMSKRYDGSQQALDLKGLRSDPDLVAQNIDVVLNRRSCMAATLRIIEENIPELLSLNLSNNRLYRLDDMSSIVQKAPNLKILNLSGNELKSERELDKIKGLKLEELWLDGNSLCDTFRDQSTYISAIRERFPKLLRLDGHELPPPIAFDVEA-PTTLPPCKGSYFGTENLKSLVLHFLQQYYAIYDSGDRQGLLDAYHDGACCSLSIPFIPQNPARSSLAEYFKDSRNVKKLKDPTLRFRLLKHTRLNVVAFLNELPKTQHDVNSFVVDISAQTSTLLCFSVNGVFKEVDGKSRDSLRAFTRTFIAVPASNSGLCIVNDELFVRNASSEEIQRAFAMPAPTPSSSPVPTLSPEQQEMLQAFSTQSGMNLEWSQKCLQDNNWDYTRSAQAFTHLKAKGEIPEVAFMK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B623-1", "uniprot_id": "A0ACD6B623_DANRE", "id": "A0ACD6B623-1", "name": "Nuclear RNA export factor 1", "aln": "MATADDSRYYNEHDD-RVGGPKHRNRKGRGPFRAPLYSDQMSRPRHRGGHSGGGGGGGGGGGPGPRS-RLHDDDGDVTMSDIPQDSSQRRYNPYGRQQNRRDDRNRKGGRGGGGNDDRGGNRFGGRGGGGGGGGGGGLSDGRSKNWFKMTIPYGKKYDKDWLLSSLQSVCPIPFHAVQYHLDGNRAQFYVEDSTTANAIFKVSRRITDKDGYKVAVIMNSCPPPTLIHSDLKPADLEHLKQCMAKRFDGSQQALDLNNIRVDPDLVSQNIEVTLNRKNSMCAVIKIIEENIPELVCLNLSNNRLFRLDDLVDIIHKVPNLKILNLSHNELKTERELDKLKGLKLVDLSLEGNPLCHHFKIHADYISAIRERFPKLLKLDGHDLPPPIGFDLDDGPSTLPPSKASYFCSEEIKNIILCFLQQFYNIYDSGNRQPLLDAYHDGATFSLSIPFVSLNPSKSTLGEYQKDSRNIKRMKDPTTRYRLIKHTRLNVVAFLNELPKTQHDIASFVVDVNTYTATLLAFTVCGVFKEMDGKSRETYRAFSRVFIAVPAGSTGLCIVNDELFVRNATTEEIRRAFVAPAPTPSSSPVPTLSAHQQEMLAAFSLKSGMNLEWSQKCLQDNDWDFERAAQIFTGLKAQGKIPDVAFVK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:.: *.**** **. * :*.:******* : * *. .* **.* :* *:.:*****:*.* .**..: ***** : ***.* : ** . . **.* .** :*****:*****:**** **** :** *.:** .:::* :..**:*:***::**.*: *. :* *::. ::::*:*:..** : .:*** ::*:** *:**:**.******:.:* *****:***:*.***:..*.*.::*********:.****.***::***: .*::*.**** **** ****:******:***** :* *: *.:*. * :: *************:****:*****.**:: *: ***.*.*** :*::*.::* ****:* *****:** ** ****** *****: . ** :..*.** *****:*::*:** *:**:********************: :****:.: *:***.*:* *****:*****:: ***:*.******..:**************:.***:***. .*************..***** *** :***************:**: *:** ** ***:*:**:***:*", "identical_positions": 372, "similar_positions": 161, "identity": "57.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2592", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JMD2-1", "uniprot_id": "SMBT1_RAT", "id": "Q9JMD2-1", "name": "Scm-like with four MBT domains protein 1", "aln": "MNGEQQLDADLGSGVEVEEFSWEDYLEETGATTAPYASFKHVDICLQSGFAPGMKLEVALRKDPE-TYWVATVITACEQLLLLRYEGYGEDRKADFWCDIRRAGLYPIGWCQQNKKTLEAPEGIRDKVSDWSAFLQRTLTGACGPPVALLEGLRNGRNPLDLIAPGSRLECQDFRDSVSTWIVTVVENIGGRLKLQYEGLE--RHDGFEHWLYYLDPFLHHIGWAAQQGYELQPPLAIRHLKNEADWQEILARVK-EEE--PLPSYLFKDKQVIRTHEFSINMKLEAVDPWSPFGISPATIAKVFDDKYFLVEIDDLRPEDHAR---RSFVCHANSPGIFPVQWSLKNGLHINPPPGFRSQDFDWADYLKQCGAEAAPQKCFPQSVSEHQFKENMKLEAVNPLFPEEVSIATVTAVRGSYLWLQLEGSKKPVPEFIVSVESMNIFPLGWCETNGHPLSTPRRARGHKLRKIAVVQPEKQILSSRTVHEGLKN-QLNSPHSVMI---NGKYCCPKIYFNHRCFSGPYLNKGRIAELPQCVGPGNCVLVLREVLTLLINAAYKPSRVLRELQLDKDSVWHGCGEVLKAKYKGKSYRATVEIVRTADRVTEFCRQTCIKLECCPNLFGPRMVLDTCSENCSVLTKTKYTHYYGKKKNKRIGRPPGGHSNLSCALKKTSKRRKRRKNIFVHKKKRSSASVDNTPVGSPQGSGGEDEDDADDGDDDSLTEGSTSEQQDELHEESEVSEKKSCSPSPTQSEMSTPLPPDTQTDKREAQTSSLSDGENKPPSPKEIRIEVDERLHLDSNPLKWSVADVVRFIRSTDCAPLARIFLDQEIDGQALLLLTLPTVQECMDLKLGPAIKLCHHIERIKFAFYEQFAN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JMD1-1", "uniprot_id": "SMBT1_MOUSE", "id": "Q9JMD1-1", "name": "Scm-like with four MBT domains protein 1", "aln": "MSGEQQLDADLGSGVEVEEFSWEDYLEETGSTTVPYASFKHVDIRLQNGFAPGMKLEVALKNDPE-TYWVATIITACEQLLLLRYEGYGEDRKADFWCDIRKAGLYPIGWCQQNKKTLEAPEGIRDKVSDWNAFLQQTLIGACGPPVSLLEGLRNGRNPLDLIAPGSKLECQDFRDSLSTWLVTVVENIGGRLKLRYEGLE--SRDGFEHWLYYLDPFLHHIGWAAQQGCDLQPPLAIKHLKSEADWQEILAKVK-EEE--PLPSYLFKDKQVIGTHEFSINMKLEAVDPWSPFGISPATIAKVFDDKYFLVEMDDLRPEDHTR---RSFVCHANSPGIFPVQWSLKNGLHINPPPGFRSQDFDWADYLKQCGAEAAPQKCFPQSISEHQFKENMKLEAVNPLFPEEVCIATVTAVRGSYLWLQLEGSKKPVPEFIVSAESMNIFPLGWCETNGHPLSTPRRARGHKLRKIAVVQPEKQILSSRTVHEGLKN-QLNSTHSVMI---NGKYCCPKIYFNHRCFSGPYLNKGRIAELPQCVGPGNCVLVLREVLTLLINAAYKPSRVLRELQLDKDSVWHGCGEVLKAKYKGKSYRATVEIVRTADRVTEFCRQTCIKLECCPNLFGPRMVLDTCSENCSVLTKTKYTHYYGKKKNKRIGRPPGGHSNLSCALKKSSKRRKRRKNIFVHKKKRSSASVDNTPVGSPQGSGGEDEEDADDGDEDSLTEGSTSEQQEELQEESEVSEKKSSSSSPTQSETPTPLPPDTQTNKRDAQTSSVSDDENKPPSPKEIRIEVDERLHLDSNPLKWSVADVVRFIRSTDCAPLARIFLDQEIDGQALLLLTLPTVQECMDLKLGPAIKLCHHIERIKFAFYEQFAN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHJ3-1", "uniprot_id": "SMBT1_HUMAN", "id": "Q9UHJ3-1", "name": "Scm-like with four MBT domains protein 1", "aln": "MNGEQQLDADAGSGMEEVELSWEDYLEETGSTAVPYGSFKHVDTRLQNGFAPGMKLEVAVRTDPE-TYWVATVITTCEQLLLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGIRDKVSDWDEFLRQTLIGACSPPVPLLEGLRNGRNPLDLIAPGSRLECQAFQDSLSTWIVTVVENIGGRLKLRYEGLE--SSDNYEHWLYYLDPFLHHVGWAAQQGYELQPPSAIRHLKNEAEWQEILAKVK-EEEEEPLPSYLFKDKQVIGIHTFSVNMKLEAVDPWSPFGISPATVVKVFDEKYFLVEMDDLRPENHAR---RSFVCHADSPGIFPVQWSLKNGLHISPPPGYPSQDFDWADYLKQCGAEAAPQRCFPPLISEHEFKENMKLEAVNPILPEEVCVATITAVRGSYLWLQLEGSKKPIPECIVSVESMDIFPLGWCETNGHPLSTPRRARVYKQRKIAVVQPEKQVPSSRTVHEGLRNQELNSTESVMI---NGKYCCPKIYFNHRCFSGPYLNKGRIAELPQCVGPGNCVLVLREVLTLLINAAYKPSRVLRELQLDKDSVWHGCGEVLKAKYKGKSYRATVEIVKTADRVTEFCRQTCIKLECCPNLFGPRMVLDKCSENCSVLTKTKYTHYYGKKKNKRIGRPPGGHSNLACALKKASKRRKRRKNVFVHKKKRSSASVDNTPAGSPQGSGGEDEDDPDEGDDDSLSEGSTSEQQDELQEESEMSEKKSCSSSPTQSEISTSLPPDRQRRKRELRTFSFSDDENKPPSPKEIRIEVAERLHLDSNPLKWSVADVVRFIRSTDCAPLARIFLDQEIDGQALLLLTLPTVQECMDLKLGPAIKLCHHIERIKFAFYEQFAN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PVD7-1", "uniprot_id": "A0A8M9PVD7_DANRE", "id": "A0A8M9PVD7-1", "name": "", "aln": "MS-LEALESDADSGQDVSEFNWDDYLEESGALSVPHHAFKHVDQGLETGLTPGMKLEVCVRTESESVYWVATIITTCGQLLLLRYEGYQDDRRADFWCDIMTADLHPIGWSKQQGRMMKPPEGVREKHQDWEALLEKALAESCSVPASLLEGAQRGCNPIDLLSPGLNVELVDHQDAGVVWSAVIEKNIGGRLRLRYAGTDGLPENQSITWVFYLDPLLHLSGWAQEHNCTLRPPAALLPLRTEPEWEEVKKSISSQEQDSSISEEFYRDRSAITPHCFTEGMKLEAVDPAAPFTISPATVAKVFNEQFFLVLMDDMRDEAQKEGGAHSFLCHRDSPGIFPTQWSLKNGVKLSPPPGFQGQDFDWADYLKQCEAEAAPQQCFPPDPSDQCIKESMMLEAVNPICPENIHVATVTKVKGQHMWIRLEGLKQAMPEIIVHTDSMDIFPVSWCETNGYPLLHPCKPRVEKQRKVAVVQPEKHRVPSKDSSPDTTKQHMNSSQAEMAGQANGKYCCPKIYFNHRCFSGPYLNKGRIAELPQCVGPGNCVLVLKEVLTLLINSAYKPSRVLRELQLDQEGRWQGHGETLKAKYKGKSYRATVEIVRTADQVADFCRKTCIKLECCPNLFGPRMVLEHCSENCSVLTKTKYTYYYGKKKSRRVGRPPGGHSNLEGGVKRRGRRRKRRKQLFVHKKRRSSASVDNTPAGSPQGSG--DEEDLDE--DDSLSEDTGSEMQDELMDDSEYSEKKSQPPTPSPSPPETPRP---TRRRRKARSPSCSDDENRPPSPKSPRTEVPQKLCLDSSPLEWSVTDVVRFIRTTDCAPLARIFMDQEIDGQALLLLNLPTVQECMDLKLGPAIKLCHHIERVKLAFYQQFAS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : *::* .** : *:.*:*****:*: :.*: :***** *:.*::*******.::.:.* .*****:**:* *******:** :**:******* *.*:****.:*: : ::.***:*:* .**. :*.::* :*. *..**** :.* **:**::** .:* .:*: .* ..: :******:*:* * : : *::****:** *** ::. *:** *: *:.*.:*:*: :. :*: .:.. :::*:..* * *: .******** :** *****:.***::::*** :**:* * : . :**:** :******.*******:::.****: .************ ******:*** *:: :**.* ******: **:: :**:* *:*.::*::*** *:.:** ** .:**:***:.******:** * :.* * **:*******: .*: . : .:**..: * ******************************************:********:**************::. *:* **.*****************:***:*::***:******************: **************:******.:*:********** .:*: .:******::*****:**********.******* **:* *: :***:*.: ** *:** ::** ***** ..:*: * *. * :*. :: * **.**:*****. * ** ::* ***.**:***:*******:**********:************.************************:*:***:***.", "identical_positions": 518, "similar_positions": 219, "identity": "59.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-260", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJP0-1", "uniprot_id": "S20A1_RAT", "id": "Q9JJP0-1", "name": "Sodium-dependent phosphate transporter 1", "aln": "-MASTLAPITSTLAAVTASAPPKYDNLWMLILGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLKQACILASIFETVGSALLGAKVSETIRKGLIDVEKYNATQDLLMAGSVSAMFGSAVWQLVASFLKLPISGTHCIVGATIGFSLVAKGQEGIKW--SELIKIVMSWFVSPLLSGIMSGILFFLVRAFILRKA---DPVPNGLRALPIFYACTIGINLFSIMYTGAPLLGFDKLPLWGTILISVGCAVFCALIVWFFVCPRMKRKIEREVKSS-PSESPLMEKKNNLK-DHEETKMAPGDVENRNPVSEVVCATGPLRAVVEERTVSFKLGDLEEAPERERLP-MDLKEETNIDGTINGAVQLPNGNLVQFSQTVSNQINSSGHYQYHTVHKDSGLYKELLHKLHLAKVGDCMGDSGDKPLRRNNSYTSYTMAICGMPLDSFRAKEGEQKGDEMETLTWPNADTKKRIRMDSYTSYCNAVSDLHSESEMDMS-VKAEMGLGDRKGSSGSLEE-WYDQDKPEVSLLFQFLQILTACFGSFAHGGNDVSNAIGPLVALYLVYETRDVTTKEATPIWLLLYGGVGICMGLWVWGRRVIQTMGKDLTPITPSSGFSIELASAFTVVVASNIGLPISTTHCKVGSVVSVGWLRS---KK----------------------AVDWRLFRNIFMAWFVTVPISGVISAAIMAVFKHIILPV------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61609-1", "uniprot_id": "S20A1_MOUSE", "id": "Q61609-1", "name": "Sodium-dependent phosphate transporter 1", "aln": "-MESTVATITSTLAAVTASAPPKYDNLWMLILGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLKQACILASIFETVGSALLGAKVSETIRNGLIDVELYNETQDLLMAGSVSAMFGSAVWQLVASFLKLPISGTHCIVGATIGFSLVANGQKGVKW--SELIKIVMSWFVSPLLSGIMSGILFFLVRAFILRKA---DPVPNGLRALPIFYACTIGINLFSIMYTGAPLLGFDKLPLWGTILISVGCAVFCALIVWFFVCPRMKRKIEREVKSS-PSESPLMEKKSNLKEDHEETKMAPGDVEHRNPVSEVVCATGPLRAVVEERTVSFKLGDLEEAPERERLP-MDLKEETSIDSTINGAVQLPNGNLVQFSQTVSNQINSSGHYQYHTVHKDSGLYKELLHKLHLAKVGDCMGDSGDKPLRRNNSYTSYTMAICGMPLDSFRAKEGEQKGDEMETLTWPNADTKKRIRMDSYTSYCNAVSDLHSESEMDMS-VKAEMGLGDRKGSSGSLEE-WYDQDKPEVSLLFQFLQILTACFGSFAHGGNDVSNAIGPLVALYLVYK-QEASTKAATPIWLLLYGGVGICMGLWVWGRRVIQTMGKDLTPITPSSGFSIELASALTVVIASNIGLPISTTHCKVGSVVSVGWLRS---KK----------------------AVDWRLFRNIFMAWFVTVPISGVISAAIMAVFKYIILPV------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WUM9-1", "uniprot_id": "S20A1_HUMAN", "id": "Q8WUM9-1", "name": "Sodium-dependent phosphate transporter 1", "aln": "-----MATLITSTTAATAASGPLVDYLWMLILGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLKQACILASIFETVGSVLLGAKVSETIRKGLIDVEMYNSTQGLLMAGSVSAMFGSAVWQLVASFLKLPISGTHCIVGATIGFSLVAKGQEGVKW--SELIKIVMSWFVSPLLSGIMSGILFFLVRAFILHKA---DPVPNGLRALPVFYACTVGINLFSIMYTGAPLLGFDKLPLWGTILISVGCAVFCALIVWFFVCPRMKRKIEREIKCS-PSESPLMEKKNSLKEDHEETKLSVGDIENKHPVSEVGPATVPLQAVVEERTVSFKLGDLEEAPERERLPSVDLKEETSIDSTVNGAVQLPNGNLVQFSQAVSNQINSSGHYQYHTVHKDSGLYKELLHKLHLAKVGDCMGDSGDKPLRRNNSYTSYTMAICGMPLDSFRAKEGEQKGEEMEKLTWPNADSKKRIRMDSYTSYCNAVSDLHSASEIDMS-VKAEMGLGDRKGSNGSLEE-WYDQDKPEVSLLFQFLQILTACFGSFAHGGNDVSNAIGPLVALYLVYDTGDVSSKVATPIWLLLYGGVGICVGLWVWGRRVIQTMGKDLTPITPSSGFSIELASALTVVIASNIGLPISTTHCKVGSVVSVGWLRS---KK----------------------AVDWRLFRNIFMAWFVTVPISGVISAAIMAIFRYVILRM------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PFM1-1", "uniprot_id": "S20AB_DANRE", "id": "Q6PFM1-1", "name": "Sodium-dependent phosphate transporter 1-B", "aln": "MVSTTLATITIMSTLVGYTTGPLTDYMWLLIVGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLRQACILASIFETLGSVLLGAKVSETIRKGIIDVTMYKDIEHVLMAGSVSAMFGSAVWQLAASFLKLPISGTHCIVGATIGFSLVAKGQQGVKW--LELLRIVASWFLSPLLSGVMSAVLFYFVRMFILQKK---DPVPNGLRALPFFYAVTMGINLFSIMFTGAPMLGFDKLPWWGVLLISIGFGIITALIVWFAVCPRLKKKIECEVKSSSPSESPLMEKR----ELHEAHSPILKPVPEESSVLSSSTPTTPPLPPPEERRVTFDIGDSDDADQK------DCKESDLGGAPKTAHVHFTNG---------PAHIPSNGYSQYHTVHKDSGLYKDLLHKLHLAKVGDCMGEGGDRPIRRNNSYTSYTMAIIGMHGD-FKPKESEFRASEDGDKEKAGAQERKRIRMDSYTSYCNAVAENGTPEDLGEGEVTLEMVDEDAGSSRSSLEEDRTDADKPEVSMLFQFLQILTACFGSFAHGGNDVSNAIGPLVALWLVYESGSVISSAPTPIWLLLYGGVGICVGLWVWGRRVIQTMGRDLTPITPSSGFSIELASAVTVVVASNIGLPVSTTHCKVGSVVAVGWLRS---RK----------------------AVDWRLFRNIFMAWFVTVPISGLISAAIMALFNYVIL--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTG0-1", "uniprot_id": "Q9VTG0_DROME", "id": "Q9VTG0-1", "name": "Phosphate transporter", "aln": "-----MESFAP-------------ELLWMVVIGFLIAFVLAFGIGANDVANSFGTSVGSGVLTIRQACVLATICEISGAVLIGYKVSDTMRKGILEVGLYEGAEEVLMLGCVAALASSAVWLLVATFLKLPISGTHSIVGSTIGFSLVARGVQGLKW--STLGTIVGSWFISPVLSGIVSILLFLAIRRFILRAQ---EPLKAGFRSLPIFYGVTFFINVISVVLDGPKLLYMDNIPTWIALTASFGLSLLVALLTQLVVVPLQRRKIAKRLRAENPVKFNFEDSVESSPSGSPKKQRRPLSLVSEGKPLPAIAEITELVSLSDNSPRTFKLAPFGLAAKNNN----ALGEEYKIDPQLIKKAEDLLG-------------KASLDNTDLTITSLN-FIDEQQQQQQQQQNGRKLQECFKRMQSPKEEQKSKTNSIG------TDLETGSTKATNNNLQVVESGGSLDLMISSTLSPNSSKVPLIESKEALNEQEEELKRTTGGGRRTSGAEET-------PEISMLFSFLQILTATFGSFAHGGNDVSNAIGPLIALYMIYREGSVMQQAESPIYILIYGGIGISVGLWLWGRRVIETIGNDLTKITSSTGFTIEVGAAITVLLASKIGLPISTTHCKVGSVVFVGHVSASGRKKKSQPNDQTDKETHNEVAPMDDGSVDWHLFRNIAYAWIVTVPVTALLSAGMMYVLCAIAVDDMGGA--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38361-1", "uniprot_id": "PHO89_YEAST", "id": "P38361-1", "name": "Phosphate permease PHO89", "aln": "--------------------MALHQFDYIFAIAMLFAFLDAFNIGANDVANSFASSISSRSLKYWQAMVLAGLCEFLGAVLAGARVSGTIKNNIIDSSIFTNDPAVLMLTMTSALIGSSCWLTFATAIGMPVSTTHSIVGGTIGAGIAAGGANGVVWGWSGVSQIIASWFIAPILAGAIAAIVFSISRFSVLEVKSLERSIKNALLLVGVLVFATFSILTMLIVWKGSPNLHLDDLSETETAVSIVLTGAIASIVYFIFFYPFYRRKVL-----------------------DQDWTLKLIDIFRGPSFYFKSTDDIPPMPEGHQLTIDYYEGRR------------NLGTTVSVEDEENKAASNSND--------------------------------SVKNKEDIQEVDLVRTETEPETKLSTKQYWWS------------LLKQGPKKWPLLFWLVISHGWTQDVIHAQVNDRD------------------MLSGDLKGMYERSKFYDN--------RVEYIYSVLQAITAATMSFAHGANDVANATGPLSAVYVIWKTNTIGAKSEVPVWVLAYGGVALVIGCWTYGYNIIKNLGNKMILQSPSRGFSIELAVAITTVMATQLGIPTSTTQIAVGGIVAVGLCNK------------------------DLKSVNWRMVAWCYSGWFLTLPIAGLIAGIINGIILNAPRFGVEYQMT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::. :.:::**: **.:*********.:::.* :. ** :** : * *:.* * :** *:::.::: : :** .:*: .*: * *: : :*:* **.***.*** .:.* * :*: * : *: ***::*:*:* :: ::* * :*. .: .: : .: *. * : :: *. * :*.:. . . . : ::: : . * ::*: : . .: : . . . . :: . : . : . .:. : . : . . : . . . : .:. ::..** :** *****.***:** *** *::::: . *:::* ***:.: :* * :* .:*:.:*..: :.* **:**:. *.*.::*:::*:* ***: **.:* ** :*:*::. .*::*:*::.:::. : :: ", "identical_positions": 113, "similar_positions": 185, "identity": "15.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2602", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GJX9-1", "uniprot_id": "A0A8I6GJX9_RAT", "id": "A0A8I6GJX9-1", "name": "Insulinoma-associated protein 1", "aln": "MDGPIWRLRAPRRRHTKPRHVRLPIEEQQTVKGGGAGRVPGPGGAAAPGAAGRGGRGARAGAPRPQVHLPHLPGDPRVPAPFLPLCRPPALVGGGAADALIGSGGSGRREQWPPPPVKRERRPGPGTGTRVRSAEPGQQPRAPRESRSRRVQPVRRRPLHRANMPRGFLVKRSKKSTPVSYRVRGGEDCDRALLLSPGCGGARAEPPVPS--PGPLPPPPPPALAERAHAALAAALACAPGPPPPPP-GPRAAHFGNPEAAHPAPLYSPTRP-VSREHEKHKYFERSFNLGSPVSAESFPTPAALLAGGGGGANGAGGGGGGTCGGDALLFAPAELKMG---TAFSAGAEAARGPGPGPPLSPAAALRPPGKRPAAPAAVAAEPPAKAAKAPSAKKPKAIRKLHFEDEVTTSPVLG-----------LKIKEGPVEA----------PRGRAGGATRPLGEFICQLCKEEYADPFALAQHKCSRIVRVEYRCPECAKVFSCPANLASHRRWHKPRPAPAAARAPEPEAATRAEAREAAGGGGSSDRDTPSPGGVSESGSEDGLYECHHCAKKFRRQAYLRKHLLAHHQALQAKGAPPPPPPPPPPPAEDILAFYAGPDEKAPQEASGDGEAVGVLGLSAATECHLCPVCGETFPS-----------------------------------KGAQERHLRLLH-AAQVFPCKYCPATFYSSPGLTRHINKCHPSENRQ-VILLQVPVRPAC---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q63ZV0-1", "uniprot_id": "INSM1_MOUSE", "id": "Q63ZV0-1", "name": "Insulinoma-associated protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRGFLVKRSKKSTPVSYRVRGGEDSDRALLLSPGCGGARAEPPVPS--PGPLPPPPPPALAERAHAALAAALACAPGPPPPPPPGPRAAHFGNPEAAHPAPLYSPTRP-VSREHEKHKYFERSFNLGSPVSAESFPTPAALLAGGGSGANGAGGGGGGTCGGDALLFAPAELKMG---TAFSAGAEAARGPGTGPPLSPAAALRPPGKRPAPPAAVATEPPAKAAKAPSAKKPKAIRKLHFEDEVTTSPVLG-----------LKIKEGPVEA----------PRGRAGGATRPLGEFICQLCKEEYADPFALAQHKCSRIVRVEYRCPECAKVFSCPANLASHRRWHKPRPVPAAARAPEPEAATRAEAREAAGGG-SSDRDTPSPGGVSESGSEDGLYECHHCAKKFRRQAYLRKHLLAHHQALQAKGAPPPPPPPPPP-AEDILAFYAGPDEKAPQEASGDGEAAGVLGLSATAQCHLCPVCGETFPS-----------------------------------KGAQERHLRLLH-AAQVFPCKYCPATFYSSPGLTRHINKCHPSENRQ-VILLQVPVRPAC---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01101-1", "uniprot_id": "INSM1_HUMAN", "id": "Q01101-1", "name": "Insulinoma-associated protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MPRGFLVKRSKKSTPVSYRVRGGEDGDRALLLSPSCGGARAEPPAPSPVPGPLPPPPP---AERAHAALAAALACAPGPQPPPQ-GPRAAHFGNPEAAHPAPLYSPTRP-VSREHEKHKYFERSFNLGSPVSAESFPTPAALLGGGGGGG-ASGAGGGGTCGGDPLLFAPAELKMG---TAFSAGAEAARGPGPGPPLPPAAALRPPGKRPPPP--TAAEPPAKAVKAPGAKKPKAIRKLHFEDEVTTSPVLG-----------LKIKEGPVEA----------PRGRAGGAARPLGEFICQLCKEEYADPFALAQHKCSRIVRVEYRCPECAKVFSCPANLASHRRWHKPRPAPAAARAPEPEAAARAEAREAPGGG--SDRDTPSPGGVSESGSEDGLYECHHCAKKFRRQAYLRKHLLAHHQALQAKGAPLAPP------AEDLLALYPGPDEKAPQEAAGDGEGAGVLGLSASAECHLCPVCGESFAS-----------------------------------KGAQERHLRLLH-AAQVFPCKYCPATFYSSPGLTRHINKCHPSENRQ-VILLQVPVRPAC---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T3H2-1", "uniprot_id": "INS1B_DANRE", "id": "Q7T3H2-1", "name": "Insulinoma-associated protein 1b", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MPKGFLVKRNKKAALVSYRIRTDED-----------GGPTPECPIAQ---IALSSPAPS--ASKPDSILLAFPSAGAEAPVPVH---KPVQFGNPEAVYQA-LYSPTRP-VSKDHDR-KYFERSLNLGSPISAESFPTPASLTS-----------------LDHHLLFAPVDLKIG---TSNSNRSGTASG-------AHAPAIQTGAKRP------SADAAERKVSSKSAKKPKAIRKLNFEDEVTTSPVLG-----------LKIKEGPVDLK---------PRPSSGGTNKPLGEFICQLCKEEYSDPFSLAQHKCSRIVRVEYRCPECEKVFSCPANLASHRRWHKPRVQSAPKQALQPAKPFPEELRAE----FPSDRDTPSPG-LSESGSEDGLYDCQHCGKRFKRQAYLRKHILG-HQALQNQ----------------ILGEAFRSAESPDAMPSEDRQSPAPLNLSP-ADCLTCPACGEKLPN-----------------------------------RASLERHLRLLHDDAQAFPCKFCPATFYSSPGLTRHINKCHPTENRQ-VILLQMPVRNAC---------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KH20-1", "uniprot_id": "A0A0B4KH20_DROME", "id": "A0A0B4KH20-1", "name": "", "aln": "------MMNMNPPTHPHPHHHPHPHPHPQPQSHLQSVQHLGQHQPLPALLQGHPDTTHFVECRALPAINETFPQFGQHRPAISLLSPLDLSLRAAASVVPITPPSTPSPPRKRQRLMSEENYLWRPHMASPAAPAPVVPSSLAMQPGYFHHHQQQQHQLPHQQHHQPYATRSSLEGASFNKSHFHGTKNNFEQIPAGQSSVSSPIYVEDETIVLTEDEDETVVSSHDYNEYATDTEEVNEGDDETQQVQVSVNGDDDEEEVFVDVLGSDDDEDEATDLVATRLQAQLIETTALKRNELLYEDEELHNQAVNGLARLFDRDFPEPDVEVSGLAELQSNSGKTYTDLSGVATAEIRTTSSDNLPPPPPPPPPPATSTIPATPPLPPPPISRPHKAERRRSKLRKHMAIDEETISPVSGTIIRKLRDDEELVVRKGDIDPAFNVVEITEEAKAILASIDNKIGDYMCQLCRTVYDDAFMLAQHRCPRIVHIEYKCSECEKVFNCPANLASHRRWHKPKAEAAGVNPAKKRVVETGDLVQEATR--------------SGDDASDGIYPCHICGKTFRRQAYLKKHQASHQMLDNLKNLDFFKSQQQQLTINGHQLADHVQLQHTTGQAVTSAAPYASLPRPPPGMPMYPPPSGKNYPGGQRFPGFPFQSFDQRRFYSLGEFYLSQHLERSSAFQYVQANHLRQLSNVAQTLMPPLPVKXPNPNTNVLRPVPRIAATATATGPPAAATATRQAATAAGVSSVGHAFNWVAPSTAGATATGSATATATATTAESGGNVIM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V3B8-1", "uniprot_id": "Q9V3B8_DROME", "id": "Q9V3B8-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MAQIQTPIPIPAPAEPIEKLSHPHSIGIQLQHKGMPHG------------------------LGLLTTVASLPPKYRSRYLNLKTRCEIPLDLTLKLPSPLPSSDVPMAATFAEVYSENTSASSSEVQGEVTKVEELPVKPPTPPQSPAGKRKLSRES--------------YDDEPAKMAKKEEEVP----VETVESTPAKPVKVAESAPKTNKASTSSGKPSRN--KATRKLKFDEETSSPVSGTVIRPLEDITDGSMQYSNG----------DIDPKYNIVEIT-------EETKAELAAIKNVIGDYVCRLCKIKFEDAFGLARHRCACIVLLEYRCPECGKQFNCPANLASHRRWHKPRKEASKKENRNTTNQPEKQQQVE------------------KKSEEELAFDCQECGKKFKRAAYLRKHQLTHQKKEKPA-------------------------EKQLEMKPTTTTITGSFHFNQAVSTSSSASSSHSDEG-----------------------------------VYVVGSNARENYDYDNDYLSDSSSSASSAGYGRLQIVEHG-LTEEESIAAAALTNLRNCASVIQHTTMAH-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. .. . . . . . . : * : : . : . : * . :* : : : : . . . . . . . . :* : : . * : : . :: .: .. . :*:::*:**: : *.* **:*:*. ** :**:*.** * *.**************: .: . : : .. .: : *: *.* *:* ***:** : : : . : . .... . : * : .. . : : : : * .. ", "identical_positions": 50, "similar_positions": 98, "identity": "6.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2614", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08774-1", "uniprot_id": "RGS12_RAT", "id": "O08774-1", "name": "Regulator of G protein signaling 12", "aln": "----------------------------MYRAGEPGKR-QSGPAPPR---------------------VRSVEVARGRAGYGFTLSGQAPCVLSCVMRGSPADFVGLRAGDQILAINEINVKKASHEDVVKLIGKCSGVLRMVISEG-SSHVEPSSSDEEGGLCEG--KGWLRPKLDSKALG-INRAERVVEEVQSGGIFNMIFESPSLCASGSEPLKLK-QRSLSESAALRLDVGQDSLCTPHPSMLSKEEISKVINDDSVFTVGLDNHDDFGLDASILNVAMVVGYLGSIELPSTSSNLEHDSLQAIRGCMRRLRAEQKIHSLVTMKVMHDCVQLVTDRAGVVAEYPAEKLAFSAVCPD-DRRFFGLVTMQTN----------DDGCLAQEDEGALRTSCHVFMVDPDLFHHKIHQGIARRFGFACTADPDTSGCLEFPASSLPVLQFISVLY---------------RDMGELIEGVRARAFLDGDADAHQNNSTS---SNSDSGIG-NFNQEEKSNRVLVVDLGGGSS--RHGQGSSPGWESVSGRGSQPWSAPWNGTFCHDSEAGSPLETSPNTDRFWDLTKHSGPVFHMEVPPATLRSS------------IPPSKRGATGSSCGFNQRWLPVHVLQEWQCGHASDQ-ESYTDSTDGWSSVNCGTLPPPMSKIPADRYRVEGSFAQAPLSTQKRDWSRKAFGMQNLFGPHRNVRKTKEDKKSSKLGRGVALAQTSQRTSARRSFGR-----SRRFSLTRSLDDLESATVSDGELTG--ADLKDCISNNSLSSNASLPSVQSCRRLRERR--------------------------------------VASWAVSFERLLQDPVGVRYFSDFLRKEFSEENILFWQACECFSHVPAHDKKELSYRAREIFSKFLCSKATTPVNIDSQAQ-LADDILNAPHPDMFKEQQLQIFNLMKFDSYTRFLKSQLYQECVLAEVEGRTLPDSQQVPSSPA-SKHSISSDHSNVSTPKKLSGKSKSGRSLNEDVGEEDSEKKRKGAFFSWSRSRSTGRSQKKKDHGDHAHDALHANGGLCRRESQGSVSSAGSLDLSEACR--------------TSALERDKAAKHCCVHLPDGTSCVVAVKSGFSIKEILSGLCERHGINGAAVDLFLVGGDKPLVLHQDSSILATRDLRLGKRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVAKYGLDLGSLLVRLSGEKEPLDLGAPISSLDGQRVILEERDPSRGKVSTEKQKGAPVKQSSAVNSSPRNHSAMGEERTLGKSNSIKIRGENGKSAR-------DPRLSKREESIAKIGKKKYQKINLDEAEEFFELISKAQSNRADDQRGLLRKEDLVLPEFLRL---PPGSSELALSSPPP-VKGFSKRAVTS---------HGQEGAVQTEESYSDSPATSPASAQSPCSAYSPGSAHSPGSAHSPGSAHSTPGPPGTAQPGEKP------TKPSCIS---TVQEGTTQAWRRLS---PELEAGGIQTVEEEQVADLTLMGEGDISSPNSTLLPPPPLPQDTPGPTRPGTSRF-----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CGE9-1", "uniprot_id": "RGS12_MOUSE", "id": "Q8CGE9-1", "name": "Regulator of G protein signaling 12", "aln": "----------------------------MYRAGEPGKR-QPGPAPPR---------------------VRSVEVARGRAGYGFTLSGQAPCVLSCVMRGSPADFVGLRAGDQILAINEINVKKASHEDVVKLIGKCSGVLHMVIAEG-TSHVESCSSDEEGGLYEG--KGWLRPKLDSKALG-INRAERVVEEVQSGGIFNMIFESSSLCASGPEPLKLK-QRSLSESAALRLDAGQAGLCAPHPSMLSKEDISKVINDDSVFTVGLDSHDDFGLDASILNVAMVVGYLGSIELPSTSSNLEHDSLQAIRGCMRRLRAEQKIHSLVTMKVMHDCVQLVTDRAGVVAEYPAEKLAFSAVCPD-DRRFFGLVTMQTN----------DDGGLAQEDEGALRTSCHVFMVDPDLFHHKIHQGIARRFGFACTADPDTSGCLEFPASSLPVLQFISVLY---------------RDMGELIEGVRARAFLDGDADAHQNNSTS---SNSDSGIG-NFNQEEKSNRVLVVDLGGGSS--RHGQGSSPGWESGGGRGSQPWSAPWNGAFCHDSEAGSPLETSPNTDRFWDLTKHSGPVSHMEVPPATLRSS------------IPPSKRGAAGSSCGFNQRWLPVHVLQEWQCGHASDQ-ESYTDSTDGWSSVNCGTLPPPMSKIPADRYRVEGSFAQAPLSTQKRDWSRKAFGMQNLFGPHRNVRKTKEDKKSSKLGRGVALAQTSQRTSARRSFGR-----SRRFSITRSLDDLESATVSDGELTG--ADLKDCISNNSLSSNASLPSVQSCRRLRERR--------------------------------------VASWAVSFERLLQDPVGVRYFSDFLRKEFSEENILFWQACECFSHVPAHDKKELSYRAREIFSKFLCSKATTPVNIDSQAQ-LADDILNAPHPDMFKEQQLQIFNLMKFDSYTRFLKSQLYQECVLAEVEGRTLPDSQQVPSSPA-SKHSISSDHSNVSTPKKLSGKSKSGRSLNEDVGEEDSEKKRRGAFFSWSRSRSTGRSQKKKDHGDHAHDAPHANGGLCRRESQGSVSSAGSLDLSEACR--------------TSALEKDKAAKHCCVHLPDGTSCVVAVKSGFSIKEILSGLCERHGINGAAVDLFLVGGDKPLVLHQDSSILATRDLRLEKRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVAKYGLDLGSLLVRLSGEKEPLDLGAPISSLDGQRVILEERDPSRGKVSTDKQKGAPVKQNSAVNSSPRNHLAMGEERTLGKSNSIKIRGENGKSAR-------DPRLSKREESIAKIGKKKYQKINLDEAEEFFELISKAQSNRADDQRGLLRKEDLVLPEFLRL---PAGSSELALSSPPP-VKGYSKRAVTG---------HGQEGAAQTEESYSDSPATSPASAQSPCSAYSPGSAHSPG------SAHSTPGPPGTTQPGEKP------TKPSCVS---MVQEGTTQAWRRLS---PEMEAGGIQTVEDEQVADLTLMGEGDISSPNSTLLPPPPTPQDTPGPPRPGTSRF-----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14924-1", "uniprot_id": "RGS12_HUMAN", "id": "O14924-1", "name": "Regulator of G protein signaling 12", "aln": "----------------------------MFRAGEASKRPLPGPSPPR---------------------VRSVEVARGRAGYGFTLSGQAPCVLSCVMRGSPADFVGLRAGDQILAVNEINVKKASHEDVVKLIGKCSGVLHMVIAEG-VGRFESCSSDEEGGLYEG--KGWLKPKLDSKALG-INRAERVVEEMQSGGIFNMIFENPSLCASNSEPLKLK-QRSLSESAATRFDVGHESINNPNPNMLSKEEISKVIHDDSVFSIGLESHDDFALDASILNVAMIVGYLGSIELPSTSSNLESDSLQAIRGCMRRLRAEQKIHSLVTMKIMHDCVQLSTDKAGVVAEYPAEKLAFSAVCPD-DRRFFGLVTMQTN----------DDGSLAQEEEGALRTSCHVFMVDPDLFNHKIHQGIARRFGFECTADPDTNGCLEFPASSLPVLQFISVLY---------------RDMGELIEGMRARAFLDGDADAHQNNSTS---SNSDSGIG-NFHQEEKSNRVLVVDLGGSSS--RHGPGGS-AWDGVGGRGAQPWGAPWTGPFCPDPEGSPPFEAAHQTDRFWDLNKHLGPASPVEVPPASLRSS------------VPPSKRGTVGAGCGFNQRWLPVHVLREWQCGHTSDQ-DSYTDSTDGWSSINCGTLPPPMSKIPADRYRVEGSFAQPPLNAPKREWSRKAFGMQSIFGPHRNVRKTKEDKKGSKFGRGTGLTQPSQRTSARRSFGR-----SKRFSITRSLDDLESATVSDGELTG--ADLKDCVSNNSLSSNASLPSVQSCRRLRERR--------------------------------------VASWAVSFERLLQDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELSYRAREIFSKFLCSKATTPVNIDSQAQ-LADDVLRAPHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQECILAEVEGRALPDSQQVPSSPA-SKHSLGSDHSSVSTPKKLSGKSKSGRSLNEELGDEDSEKKRKGAFFSWSRTRSTGRSQKKREHGDHADDALHANGGLCRRESQGSVSSAGSLDLSEACR--------------TLAPEKDKATKHCCIHLPDGTSCVVAVKAGFSIKDILSGLCERHGINGAAADLFLVGGDKPLVLHQDSSILESRDLRLEKRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVARYGLDLSGLLVRLSGEKEPLDLGAPISSLDGQRVVLEEKDPSRGKASADKQKGVPVKQNTAVNSSSRNHSATGEERTLGKSNSIKIKGENGKNAR-------DPRLSKREESIAKIGKKKYQKINLDEAEEFFELISKAQSNRADDQRGLLRKEDLVLPEFLRL---PPGSTELTLPTPAAVAKGFSKRSATG---------NGRESASQPGEQWEPVQESSDSPSTSPGSASSP------------------PGPPGTTPPGQKSPSGPFCTPQSPVS---LAQEGTAQIWKRQS---QEVEAGGIQTVEDEHVAELTLMGEGDISSPNSTLLPPPSTPQEVPGPSRPGSGTHGSRDLPVNRIIDVDLVTGSAPGRDGGIAGAQAGPGRSQASGGPPTSDLPGLGPVPGEPAKPKTSAHHATFV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7URF2-1", "uniprot_id": "A0A8N7URF2_DANRE", "id": "A0A8N7URF2-1", "name": "", "aln": "------------------------------------MRLLDRPISPA---------------------VRRVEMERGRAGYGFTIAGQAPCVLRGIIKGSPAHSVGLLPGDRVLRVNDTDVSESSHDVVVKLIGTSSKSLCLLVTSGDRPPMACCSSDEELGCQNKSKRPWLNPGIKDPFPGKLDGRDLKEPILQSVGSFDTVFEISDQGTMTPHQEKQKKQRPLSE-PDVSYWLQQQQRSKGNVDILSQDETSRVVSEDSVFSD-LQSQNDLASDSSILNVAMIVGYINSMELELVTSQTEEDALQVIRQCISKIGIEQKTHSLVLMKVKCNCVQLCDDRDVVLASYPAENLALCVICTE-DSRFFGLVSIDST----------KNIDTGRQTS-TLKTLCHVFFIDPELYEHKEHQSIIGHFGIPCTPDPDTQSCLEFPQTPHSISHFISVLY---------------ADMGDYIEKLRLKLDSENPDEGSQNARNSGSGSGSDSGIG-NASPEERDS---LIGQWSFTS--PNICNPPPPYYS------QHRNSTFLKPECR-CLLSEPLTGSAQPATPSGVPAGADGSAFTPVP-LSKQSN------------LPPKQR--------AGQRRPSIGLKARWQKSRPNSI-ECLVEGDNDDPKSKCSTLPPAMEQIPTLRY--------KPLEHTQKINFTPQLELTSRFFSSAAKQKDGENKGS------LFWALTRGRSSVRRPSGP-----AKRLSLAHSLNDLESAAS-DGERSGGGVQRHDCSSVSSLDSNGSLPSVTNHCRFTERR--------------------------------------VALWAVSFERLLQDPVGVRYFSEFLKKEFSEENILFWQACECFSQVPEHDKKQLSQKAKEIYNRFLSSKATMPVNIDSQAQ-LADDVLTAPQPNMFKQPQLQIFNLMKMDSYARFLKSTLYQECMLAEVEGRPLPDPCPIPCSPAPSKHSFTSDRSTFSTPKKENRKPKTGRSS-DDLREKHSDKK--NGFFSWYRYPSIGKGQKKREAPDLP---YHCNG---RRESQGSLSSGASQELNTSCSGGKNEQCELRGSSCALDKERERCSRTCTVTLPDGSSCSIPLRQGASIRQVLLELCQKQHINLAAVDLFLTGGEKPLVLDQDSITLSSRELRLEKRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVAKYGLQLGDLVARISGETEVLDLGVPISNLDGLRVVLERADP----AKAEKSKTLNSKTPAAKKGFPRER----------DDNSTVKPLKADVEDK-------HPRTAASE-------RKKGKKNHIDETEEFFELLSRAQSSRVDDQRGLLRKEDLVLPDFLRVNNDPKPQSPPSCSTPTSHKPGHTTTTSTNPHPPKPSPCNGHQASAPFSAPLSPILRSAGAREQEEEEGLGDLTLVAEGDISSPNSTLLPPPPPVSPPPYDGSLAEANFTPPPAVHGTGTEEENTSTSAVNSSTAQPDLRVRDKGVTLEDSFEGYAAELRQCQNKMRNGVYPSTDAPRPLSGVLEVNESDTVQYKATFV---------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCX1-1", "uniprot_id": "RGS_DROME", "id": "Q9VCX1-1", "name": "Regulator of G protein signaling loco", "aln": "MHHHHPPLPITGASGSTAVGTGAAAAEDASPAANSGPAPISTSTTPSGSNSQQHQRRRKKRANYNYNGIRTVEVRRGYNGFGFTISGQQPCRLSCIISSSPAEQAGLRSGDFLISVNGLNVSKLPHETVVQLIGNSFGSIRMQIAEN----YYSDSSDEEN------AHATLRGQLLAASLR------HKPRFLHHKAKLHRLRNSPQKKLNPPEAVEPHKSKSSPDHPTLKPVLEDPPLTANLSKAADVANVSAMVR---------------AVGSAALECRVIVGYLGTIEMPKQISHS--SKLQTVRSCIRKLRQEKRQPTIVLMCITPDSLSLQSSSGGVLATYSSARLNFVSSSSESENRFFGLVTSAVHNTQIEEEYEPSAGSAAAAGHISISHSCHVFVIDTKLIEHAQHLQRAHEFRLQCTRDPISNLCLEFPNNSEYVVNLVRSMYTMRILPPASRSHQADYEAGAGAAAAGGAVAAAHSPQPSNHSEISTTTSNSDSGIGFNNDCTNISDRILVVDFLAAGAGAAAAAHAGPPTYPAPARPLGIVGIPDNRLTVRAMPDHSALLRSPPASSSLRRPNLLASFNLIQSPATNLTSTRSCDDVLNLFVDDSPRTLAAVASMDDISLHSAAPSLDEGHTFAHPACVPRKMRRSLALETPTTPHKLSAQVFGQPGSRHSLGFEAIDSVQSSVSGACMDQTMDTWASLQNLHKSHKDRTSMSASSSSHCLLEATNSEPDLGNRALPANASPFRRAWGQSSFRTPRSDKVAKEQQQLGQSSPVRRTASMNASDNDMYIKTLMLDSDLKSSRSQHQLSLLQVPKVLTTPAPPSAITASVAAEGAAQDHGCPSSWAGSFERMLQDAAGMQTFSEFLKKEFSAENIYFWTACERYRLLESEADR--VAQAREIFAKHLANNSSDPVNVDSQARSLTEEKLADAAPDIFAPAQKQIFSLMKFDSYQRFIRSDLYKSCVEAEQKNQPLPYSG--LDLDELLKTNFHLGAFSKLKKSASNAEDRRRKSLLPWHRKTRSKSRDRTEIMADMQHALMPAPPVPQNAPLTSASLKLVCGQNSLSDLHSSRSSLSSFDAGTATG--------------GQGASTESVYSLCRVILTDGATTIVQTRPGETVGELVERLLEKRNLVYPYYDIVFQGSTKSIDVQQPSQILAGKEVVIERRVAFKLDLPDP-KVISVKSKPKKQLHEVIRPILSKYNYKMEQVQVIMRDTQVPIDLNQPVTMADGQRLRIVMVNS---DFQVGGGSSMPPKQSKPMKPLPQGHLDELTNKVFNELLASKADAAASEKSRPVDLCSMKSNEAPSETSSLFERMRRQQRDGGNIPASKLPKLKKKSTSSSQQSEEAATTQAVADPKKPIIAKLKAGVKLQVTERVAEHQDELLEGLKRAQLAR-----LEDQRGTEINFDLPDFLKNKENLSAAVSKLRKVRASLSPVSKVPATPTEIPQPAPRLSITRSQQPVSPMKVDQEPETDLPAATQDQTEFAKAPP---PLPPKPKVLPIKPSNWGVAQPTGNYCNKYSPSKQVPTSPKEASKPGTFASKIPLDLGRKSLEEAGSRCAYLDEPSSSFV-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .* :* **: ** *:***::** ** * :: .***. .** .** :: :* :*.: .*: **:***.. : : ::.. ***** : *. : :: . :. : : .. .. : : .:. .: . . . . : * :: . .:: *: ::***:.::*: *: . **.:* *: :: *:: ::* * : :.:.* . *:* *.: .* : ..: : ******: . . :: ****.:*..* .* * .* : ** ** :. ***** .. : ::: :* : * : :: * *.****** * : .. ::. . : . . .: : . * . *. .* . : . : .:. . . . .*.. : * *: . . : : :* . . : .*. : . : .. . : : * : * .: ..: : :: : . * : ** ****:***..*:: **:**:**** *** ** *** : : . .: :*:**: :.*..::: ***:****: *::: * . *::* * ***.***:*** **::* **:.*: ** :.:.** . * .: . . . . . : : :* . *..: ::: : :: . * : :.* ** .* : . : . : * : *.**:: : : * :: ::: * ::: : . *:.: *. *.: :.* * * ::: : :*. *:*** : :.:*:**.* : **:**::::*. .: : . : . :**. *:: ** *: : :. .. . * . : .: : . : . . : ... : * :: :: : . . : :.: .:. ::.. .: :. *. : . . : . . . .* . . . . :. : . . . . . *.. .* ", "identical_positions": 208, "similar_positions": 377, "identity": "12.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2617", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BZ20-1", "uniprot_id": "PAR12_MOUSE", "id": "Q8BZ20-1", "name": "Protein mono-ADP-ribosyltransferase PARP12", "aln": "---MAQAAVAVAEVTQLLCAAGGALELAELRRR--LRTSLGTDALERLLRDCGRFVVASRAVVAVGAGREAAAAASERLVLAVSSLRLCRAHQGPKPGCTGLCAQLHLCKFLIYGNCKFLKTGKNCRNGHNLKTDHNLSVLRTHGVDHLTYTELCQLLLQNDPSLLPDICLHYNKGDGPFGSCSFQKQCIKLHICQYFLQGECKFGTSCKRSHEFTNSESLEQLERLGLSSDLVSRLLSTYRNAYDIKNKGSALSKVSPSPAGPQGSSERKDSSGPVSPGTPSQEESEQICLYHIRKSCSFQEKCHRVHFHLPYRWQFLDGGKWKDLDNMELIEEAYSNPSKDRIVYTESAAGFHFDNLDFNSMKFGNTLARRLSTASSVTKPPHFILTTDWIWYWMDEFGSWQEYGRQGSGHPVTTISSSDVERAYLAFCAPGADAQAATLKFQAGKHNYELHFKAFLQKNLVYGTIRKVCRRPKYVSPQDVQMKQSCNTKLHGPKSIPDYWDPAALPDLGFKKITLSSSSEEYQKVWNIFNRTLPFYFVQKIERIQNMGLWEVYQWQKCQMQKQNGGKEVDERQLFHGTSANFVDAICQQNFDWRVCGLHGTSYGKGSYFARDAAYSHHYSKSDTHSHMMFLARVLVGDFVRGSTSFVRPPAKEGQSNAFYDSCVNSMSDPTIFVVFEKHQVYPEYLIQYSTSSKPPASPSIFVALGNLFTSRQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0J9-1", "uniprot_id": "PAR12_HUMAN", "id": "Q9H0J9-1", "name": "Protein mono-ADP-ribosyltransferase PARP12", "aln": "---MAQAG-VVGEVTQVLCAAGGALELPELRRR--LRMGLSADALERLLRQRGRFVVAVR------AG--GAAAAPERVVLAASPLRLCRAHQGSKPGCVGLCAQLHLCRFMVYGACKFLRAGKNCRNSHSLTTEHNLSVLRTHGVDHLSYNELCQLLFQNDPWLLPEICQHYNKGDGPHGSCAFQKQCIKLHICQYFLQGECKFGTSCKRSHDFSNSENLEKLEKLGMSSDLVSRLPTIYRNAHDIKNKSSAPSRVPP-LFVPQGTSERKDSSGSVSPNTLSQEEGDQICLYHIRKSCSFQDKCHRVHFHLPYRWQFLDRGKWEDLDNMELIEEAYCNPKIERILCSESASTFHSHCLNFNAMTYGATQARRLSTASSVTKPPHFILTTDWIWYWSDEFGSWQEYGRQGTVHPVTTVSSSDVEKAYLAYCTPGSDGQAATLKFQAGKHNYELDFKAFVQKNLVYGTTKKVCRRPKYVSPQDVTTMQTCNTKFPGPKSIPDYWDSSALPDPGFQKITLSSSSEEYQKVWNLFNRTLPFYFVQKIERVQNLALWEVYQWQKGQMQKQNGGKAVDERQLFHGTSAIFVDAICQQNFDWRVCGVHGTSYGKGSYFARDAAYSHHYSKSDTQTHTMFLARVLVGEFVRGNASFVRPPAKEGWSNAFYDSCVNSVSDPSIFVIFEKHQVYPEYVIQYTTSSKPSVTPSILLALGSLFSSRQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LVS6-1", "uniprot_id": "Q1LVS6_DANRE", "id": "Q1LVS6-1", "name": "", "aln": "MSDMSDCTRVIHYATSILCSNKGSMEMSQLHRRVFQRFEISEADFWYIVKKCARFVMVQSR-----PG--EEDAESDCTVVAKTSLRLCKKYS--KNECY-ECQDLHLCKYFVYGNCRYGKGRKECKFSHNIQSQHNYPLLRECTLHELNEDDLFLLLLQNDPALLPEVCAHYNKGTGVFGACTFMERCTKVHICQHFVHDTCLFGPKCKRQHSIDG-YSRRMLEERGLSGDIIRELPYIYQNVYRLNSQ-------------PQ-SSELISDQG-IKP--VAQMEKNEICLHFIRRKCKFQDQCVLVHFNLPYKWELYDGKGWRELRNMEDIERAYCDPKNE---YSPGSR-----PVNFVSMTKNGDPVRRLSTVSSVSKPAHYFLTTQWIWYYKGDHENWIEYGHPDDKQRATSVTSRELEKSFQ-------EDNNAEVTVIKGNRHYYVSFQDMYQRNPKHNTKRRVRRRPRFVSISEVESKAAQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::. .: .*.:**: *::*:.:*:** * :. : :::. .***:. .* * .: *:* :.****: :. * * * :****::::** *:: : *:*: .*.: ::** .:** :..*. :* **:**** ***::* ***** * .*:*:* ::* *:****:*::. * **..***.*.: . . . **. *:*.*:: .* *:*.: ::.: ** :** ...* :.* :* * ::***:.**:.*.**::* ***:***:*:: * *.:* *** **.**.:*. : : .: ::* :*. . .*****.***:**.*::***:****: .:. .* ***: . : .*:::* ::*::: : : * :.. *:::* : *: : *:* :.* ::* ***::** .:* : ", "identical_positions": 157, "similar_positions": 170, "identity": "21.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2621", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAN0-1", "uniprot_id": "D4AAN0_RAT", "id": "D4AAN0-1", "name": "", "aln": "MAAVYSGISFKLKSKTTSWEDKLKLAHFAWISHQCFLPNKEQVLLDWARQSLVAFYKKKLELQEDIVERLWVYVDNILHSRRLQNLLKNGKTINLQISLVKIINEKIEEFSLSGSQRSICAILSCCQGILSAPALAVIYTAKPELIVALLSQLCWSACRQP-----EGAMTAKLFEVIHLALDHYLKLQQQQANPRRVFGDMTGHLFQPCLVLRHLLLGGTWTQASQGQLWQVLSRDIRSKIDAVLRGGVFRYDLLSSYKEELLEQQQ--ENVKMGVLKNLLTPMDTVITRLVEPDYVKSD--LHALVVASSVSLLYRLFLDSYLKE-ENQFLCFQVLPRLFGCLQISHLQEGQMEALSLSDWTTELLAVEQLLNLVATSNIYNVAADRIRHGETQFHFYRRVAELLINHSQASVPAWFRCLKILMSLNHLILEPDLDDLLSSAWIDAEVTEFRAKKAQEVLINTVFQTYAKLRQMPQLFQELLEVICRPAAEALRQPLLASGLSMALCACFLELPLSQILDTWSLVLDKFQSLVMPCLQSDT-DMAFKAMSLSSLLHCIMFNMQSLDNNMPLPIIRRTQCMMERMLRELVKPLLGLLLDLWSPEPEPWQQKVSDSALLLSYTWAQVDTTLSLHCSQYYSLAVSLARAALDSSNLPLLLPGVETELWKKVEKCIAQSRSLSRYCLEQLYLQKVKRTLIRTSSQSKEALQTLRFDTAHILDSSRDCLSQKTVTAWDRQVSTMNESLYPVAHWHLIVSNLTVLIPYLCLNDVRYVATVLLRTLPTSKAQGSLAPGESYVTLEKISTALLHSPLFPEMQSLYSAFLTCIIAKCSNILCSGAHNDLSLS-QQLPWLFGKDYHTLVAHWETRLAKVGSE-GVEPRGEIAQNFLSMVKSGFPIKLHEDQLKDLLELFDVISALHLDSLWPSYHVHLFFLLFSMAVSTLG--HCSCPLALQFLVKCYQLLSGLQRGRNARSVFRVMYVSDIFEVVLTSLLQASAEFQVR-EDDPAWLQLLQVSGVFLEQLMQMLIQAKLSLVLNFGKITAFLSK---YSKGASSKELNIQNLRSRQLLLVALTKLCQSLGPCVKERRQLLEAPAALPELLQQAMMQMGAMLQLCLVPGTTGCRRRLPSVLLSAVPTLLEVDLSQHLREGQPKIAQVVDTDRALLSHVTLYQDVYTQLLEELPALSGNTQSFQAALRFLTLFLLAPEFHSKE--SSVFASIFYSVQKVLTGPCIPAPVTQDTEPHLGALLTQMFKAETTEHFGMVLQSILQGLDVTQAWRSDLQVVLCAIRLLNLLLKCPLSGEKASLLWRSCPQIVTALMLQHREACQEQPVALVVVEPILEVLAVLLRKGEESISNPHHVNLAFNILLTVPLEHLKPREFGSVFLKTHNVLFSILQCHSKVMLKAIPSFLNSFNRLLLSVLHEGRQKDQVKRWGQERCSCHSNADHLPSVGSMDDLPVVLECARLVERMYSHIATRAEEFTTFSPFLVAQYVTEVQKVTLYPPVKNLLQEGIYLILDLCMERDIQFLRASLQSGARDVFKDLHSDYLKYHKAKHEGEKRYTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q7L1-1", "uniprot_id": "E9Q7L1_MOUSE", "id": "E9Q7L1-1", "name": "", "aln": "MAAVYSGISFKLKSKTTSWEDKLKLAHFAWISHQCFLPNKEQVLLDWARQSLVAFYKKKLELQEDIVERLWIYVDNILHSKKLQNLLKDGKTVNLQLSLVKIINERIEEFSRSGCQRNICAVLSCCQGILSAPALAVIYTAKPELIVALLSQLCWSACRQP-----EGATTAKLFEVIHLALDHYLRLQQQQANPKRVFGDMTGHLFQPCLVLRHLLLGGTWTQASQGQLWQVLSRDIRSKIDAVLRAGVFRHDLLSSYKEELLEQHQ--ESVRMGVLKGLLTPMEAVIARLVEPGYVRSD--LHALVVASSVPLLFRLFLEAYLQE-ESQFLCFQVLPRLFGCLQISHLQEGQIEALSLSDWTTELLAIEQLLNSVATSNIYNVATDRIRHAETQFHFYRRVAEVLINHSQASVPAWFRCLKILISLNHLILEPDLDDLLSSAWIDAEVTEFRAKKAQEVLINTVFQTYAKLRQVPRLFEEVLGVICRPAAEALRQPLLASGLSVALSACLLELPLSQILDSWSLVLDKFQSLVMPCLQSDT-DMALKAMSLSSLLHCIMFNMQSLDNNMPLPIIRRTQCIMERMLRELVGPLLGLLLDLWSPEPELWQQKVCDSALLLSYTWAQVDATISLHCSQYYSLGISLARAALDSSNLPLLLPGVEMEFWKKVEECVGQSRSLSRYCLEQLYLQKVKRTLMRSNSQSKEALQTLRFDTAHILDSSRDCLSQKTAAAWDRQVSTMNESIYPVAHWHLIVSNLTVLIPYLCLNDVRYVATVLLRTLPASKAQGSLAHGEPHVTLEKISTALLHSPLFPEMQSLYSAFLTCIIAECSSTLCSGAHSDLSLVSQQLPWLSGKDDHTIVAHWETRLAKVGPE-GVEPRGEIAQNFLSMVKSGFPIKLDEEQLKGLLELLEVISALRLDSLSPSYHVHMFFLLFSMAVSTLG--HCSCPLALQFLVKCYRLLSSLQRGKNGRTVFRVMYVSDIFEVVLTSLLQASAEFQVR-EDDPAWLQLLQVSGVFLEQLMQMLTQVKLSLVLNFGKITAFLSR---YRKEASCKEGKIPNLRSRQLLLVALTKLCQSLGPCVKERRQLLEAPAELAELLQQAMMQMGTMLKLCLVSGTTG-RRRLPSVLLAAVPTLLEVDMSQHLRDGQPKIAQVVDTDKTLLSHGTLYQDVYTQLLEELPALSGNAQSFQAALQFLTLFLLAPELHSKE--TSVFASVFYSVQKVLTGPCIPAPVTQDTELHLGALLTQMFEAGTTEHFGMVLQSILQGLDVTQAWRSDLQVVLCAIRLLKLLLKCPLNGEKASLLWRSCPQIITALMLQHREACREQPVALAVIEPVLEVLAVLLRKGEESISNPHHVSLAFNILLTVPLEHLQPREFGSVFLKMHSVLFSILQCHSKVMLKAVPSFLNSFNRLLVSVMHEGRQKD---------------------KGSVDDLTVVLESARLVERMYSHLATRAEEFTAFSPFLVAQYVTEVQKVTLYPPVKNLLQEGIYLILDLCMERDIQFLRASLQAGARDVFKDLHSDYLKYHKAKHEGEKRYTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14146-1", "uniprot_id": "URB2_HUMAN", "id": "Q14146-1", "name": "Unhealthy ribosome biogenesis protein 2 homolog", "aln": "MAAVYSGISLKLKSKTTSWEDKLKLAHFAWISHQCFLPNKEQVLLDWARQSLVAFYKKKLELKEDIVERLWIYIDNILHSRKLQNLLKNGKTINLQISLVKIINERVAEFSLSGSQRNICAVLRCCQGILSTPALAVIYTAKQELMVALLSQLCWSACRQP-----EGAVVAQLFEVIHLALGHYLLILQQQVNPRRAFGDVTAHLLQPCLVLRHLLSGGTWTQAGQGQLRQVLSRDIRSQIEAMFRGGIFQPELLSSYKEGLLDQQQ--GDVKTGAMKNLLAPMDTVLNRLVDAGYCAAS--LHTSVVANSVALLYKLFLDSYFKE-GNQLLCFQVLPRLFGCLKISHLQEEQSKALSTSDWTTELLVVEQLLNSVANNNIYNIAADRIRHEEAQFRFYRHVAELLINHAQAPIPAWFRCLKTLISLNHLILEPDLDDLLASAWIDAEVTEFRTKKAQEALIRTVFQTYAKLRQVPRLFEEVLGVICRPAAEALRQPVLASGPSTVLSACLLELPPSQILDTWSLVLEKFQSLVLPYLQSDA-DMALKSLSLSLLLHCIMFNMRSLDSSTPLPIVRRTQCMMERMMRELVQPLLALLPDTPGPEPELWLQKVSDSVLLLSYTWAQVDAMFSLNCSQYHSMSGPLIGVALEISNLPSLLPGVKTQHWKKIEKFTAQFSSLGTYCLEQLYLQKMKRTLMQTSFRSEGAIQSLRCDAAFIIGSGRKSLNQRTTASWDGQVGMVSGLTYPVAHWHLIVSNLTILISYLCPDDVGYLASVLLRTLPMGKAQEVSIDEEAYITLEKISKAFLHSPLFPEMQSLHSAFLTCVTTSCSSILCSGAQRDSGLVSQQLPWLFEKD-HMVVGHWENRFAKAGPE-GIEPRGEIAQNLLSLVKSDFPIQLEGEQLESILGLLEVISALQLDSLLPPYHVHYFLVLLSMAVTKLGC-SCSSSLALKFLTTCYQLLGYLQKGKSARSVFKIMYGSDIFEVVLTSLFRASSRFLIE-MDDPAWLEFLQVIGTFLEELMQMLIQMKLSLVLNFRKITAFLSSSKPYTEAASSKQLENQNPQGRQLLLVSLTRLCHVLGPFLKEQKLGQEAPAALSELLQQVVLQTGAVLQLCSVPGARG--WRLPSVLISSVSTLLEADLGQHCRDGGADISQ--GSDRTLLSHVALYQGVYSQILLELPALAGHDQSFQAALQFLTLFFLAPELHPKK--DSVFTSMFHSVRRVLADPEIPVQVTQDIEPHLGALFTQMLEVGTTEDLRLVMQCILQGLDVSNMWKADVQAVVSAVTLLRLLLNCPLSGEKASLLWRACPQIVTALTLLNREASQEQPVSLTVVGPVLDVLAALLRQGEEAIGNPHHVSLAFSILLTVPLDHLKPLEYGSVFPRLHNVLFSILQCHPKVMLKAIPSFLNSFNRLVFSVMREGRQKD---------------------KGSIDDLPTVLKCARLVERMYSHIAARAEEFAVFSPFMVAQYVLEVQKVTLYPAVKSLLQEGIYLILDLCIEPDVQFLRASLQPGMRDIFKELYNDYLKYHKAKHEGEKRYTA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0V0U5-1", "uniprot_id": "URB2_DANRE", "id": "B0V0U5-1", "name": "Unhealthy ribosome biogenesis protein 2 homolog", "aln": "MAAIYSGIQLKLKNTRTPWPDKLKLARFAWISTQCLLPNKEQVLFDWTNHALTCFYNKKVEMPPEVVEGLWTYLDDILHSRKLHNVLSQGKTISLRLTVAQIINDRILDYTSGLRSVSFHTILSCCHGILTSPVLSVIYTAKYELLVQLLSRLCGLTSMQLRQQKYEEPLSLKAFEVLLVVLSNYLTVQKQQANSNRVFFQVTAHLLHPLLLLRHLLNTRVWTEKDDVKIRQNLSKEIRTKVDAVLQSALFLSDHLQSYKVEVSPSENEAGDRKSHIGKGLQGPLNTILTRICIHGASEEEEALFYAVKSNSLSLLFKFALDSFCRGGENKRVIFHLMAKLITALGFTDELDID-ENFRASNWGICLLALENLLNSCLVGDIYNVAADRIQHGEVQFNFYRKVARLLFNNTQMGVPAWYRCLRALLALNHQILEPDLDELLSAVWVDAENMELRVRKAREALVSAVLQTYSKLRQLPKLIEELLDVVCRPAADELRPALLPEAIQKTLSQCLLDNPLRQNLEICGLILKRVQSCLLPHIQDETSDLALKVFSMSLLLHAVLFSFKTLDNSTPVPVVKQTLSLMTEML-KVVEDLLEQKLATKGP----WMEKVQEVTLLLAHTWVEADALFQIHCTKYTSPSASQSSTLVD-----------------KALMLRNMDSPLGKLLQNLLALHKLKIHLLKSFSES----SEMQKMAQFILNREELSVIHSLDQMWDFQFCNVNSSTYNAAHWFLVTSNLPLIAPYLDPNDRSVFAECMLKSLLQSLDASGSNLENTGISVCLISRQLLESPVLCELPEIFSALTKCIIKALFGLLDS----------SHMQLICPSFLTPPVENVEVKDEEMGMTPSMKRLKAIGLEMLYSVKMKSSVPLSKRQINGLLQLVKVTSVLNGYAMSYEDYLELFLTLLTLTSTIQCVEETNLSAFIELLKELFSVMASLLLAKNSQSILKVIHGSNLLEATMTTLFSRSSEGLFKSLDGPTWLSFLQSVQDFIQSLIRLIIDRKSSICLNLEKFTSFMVE---CNFTARVLTVDTGDLFSLQLHLVTLSALCREMMTTLGKNKQLDQA---LTHLLEKATAVMEPAIQAVLMG--KGSCLLRQSFSVEVVTVMIRCELARASSSN--------DDGQEKISSMPFYRSFYQQILKELFPSPRPMDFLISSIHYLSAFHMAAEKTKVADLEDLHIEILQSIQALLSGTWMSLTDVKELEGPVKELLNQLMSNCSQEQFHLFLLMLREGLVAAKVEGGQCSEVLSAVTLIKLLACCLFPEHCSKAFWLITPQIISSLIFIIKESSKLPSLTRVLTVPGLEALTVLLRQGKAQISNPHQVIVVLGALQFVPLDSHCMEDYHSAFEAVHEALFAIIHCYPQVMLKASPTFLNCFYRLVSSVMHEGKQRSD------------------TDRASEKDRESLLKCARLVERMYTHVASAAEDFTVLSSFMVAQYVSELQRVTLQPEIKAHLTEGIYCILDHCVEQDIKFLNTTLQMGVKEVFNELYSSYTHYHKSQRQGEEKYTV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 470, "similar_positions": 577, "identity": "30.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2624", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BTA9-1", "uniprot_id": "WAC_HUMAN", "id": "Q9BTA9-1", "name": "WW domain-containing adapter protein with coiled-coil", "aln": "MVMYARKQQRLSDGCHDRRGDSQPYQALKYSSK------------------------------------------------------SHPSSGDHRHEKMRDAGDPSP---------------------------------PNKMLRRSDSPENKYSDSTGHSKAKN-----------VHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTS-----------DAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMA--VNSFPKDRD----YRREVMQATATSGFASGMEDKHSSDAS--------------------------SLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCT-----------TPSTSSASGLN-PTSAPPTSASAVPVSPVPQSPIPP-LLQDPNLLRQLLPALQATLQLNNS-------NVDISKINEVLTAAVTQASLQSIIHKFLTAGPSA-FNITSLISQAAQLS-TQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVP--------------IKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQ----GHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASN--------------------ATVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVCEIQATLREQRILFLRQQIKELEKLKNQNSFMV---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q924H7-1", "uniprot_id": "WAC_MOUSE", "id": "Q924H7-1", "name": "WW domain-containing adapter protein with coiled-coil", "aln": "MVMYARKQQRLSDGCHDRRGDSQPFQALKYSSK------------------------------------------------------SHPSSGDHRHEKMRDAADPSP---------------------------------PNKMLRRSNSPENKYSDSTGHNKAKN-----------VHTQRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTS-----------DAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKLA--VNSFPKDRD----YRREVMQATATSGFTSGMEDKHSSDAS--------------------------SLLPQNILSQTSRHNDKDYRLPRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTASLPAQKTERKESAPGDKSISHSCT-----------TPSTSSASGLN-PTSAPPTSASAVPVSPVPQSTIPP-LLQDPNLFRQLLPALQATLQLNNS-------NVDISKINEVLTAAVTQASLQSIIHKFLTAGPSA-FNITSLISQAAQLS-TQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVP--------------MKPLISTPPVSSQPKVSTPVVKQGPVSHSATQQPVTADKQQ----SHDPVSPRSLQRLSSQRSPSPGPNHT-CSSNAST--------------------ATVVPQNASARPACSLTPTLAAHFNDNLIKHVQGWPADHAEKQASRLREEAHNMGSVHMSEICTELKNLRSLVRVCEIQATLREQRILFLRQQIKELEKLKNQNSFMV---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7ZUK7-1", "uniprot_id": "WAC_DANRE", "id": "Q7ZUK7-1", "name": "WW domain-containing adapter protein with coiled-coil", "aln": "MVMYARKQPRLGDGCTDRR-DSQPYQTLKYSSK------------------------------------------------------SHP---DHRHEKMRDSNDATP---------------------------------PCKMLRRSDSPDNKHMDNTGHGRAKA-----------IHPHRGREREGGTSISPQENSHNHSSLHSSNSHS-----NPNKSS-----------DTPFEPADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEATKTAAVVNSFPKDRD----YRREAMQATPAS---------YSSTKS--------------------------SIATE----------------------------------------KPSSLTPS------------------------------------------------------------------SSSAAVSGLDVPNSASSASGSTVPVSPVMQSPAPPTLLQDPSLLRQLLLALQTALQLNNA-------SVDMAKINEVLTAAVTQASLQSILHKILTAGPSA-FNITTLLSQATQLSNQVAQQSSQSPMSLTSDASSPRSYVSPRISTPQTNTAS--------------LKPPLSTTPVSSQTKINAMTVKSSSLPPPSSQQPLSTEKHH----DNG-NSPRTLQRQSSQRSPSPGPNHMGSNSSSSSNNGGGGGGQGPGVVSGAMPPGSVPPGTAPGRATCSFTPTLAAHFNENLIKHVQGWPAEHVEKQASRLREEAHTMGSIYMSENCTELKNLRSLVRVCEIQATLREQRILFLRQQIKELEKLKNQNSFMV---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VX88-1", "uniprot_id": "WAC_DROME", "id": "Q9VX88-1", "name": "WW domain-containing adapter protein with coiled-coil homolog", "aln": "MVMHARKPQRMNDGYFEKHTSHTSYQSSKYSSSKRDYERDRSSNYRDRDLSPGAGGGGGGGSAGGGGGGSGNGGGPLNNGNSYRSQSPDIDSPSSRSHDLRDRSDHRGGGGGNGRGGSGERYSFMQKMRDRDRDVYKKDKYSDKRDRRGNDRDSESSYRTNHDRDRRGGGGSGGGSGKLCSSRENDKRSGSDDRDRDRDRDLRDLRDKRDRGSDRDRDMYKKDKYADKRERSDRGERTARYGDWSEHVSSSGKMYYYNCKTEISQWEKPKEWVDRERNLPRDQHREKDYRDKDRDRDRDDRFSRSTYKHSNSSRDNSRLRWNYDNDGGPPSHRRRLDGRHNDNADMDISGDSTPTSEASYSLSGTPTTHGGGPGGGGPGGGGGSNSDQPMGNALPRLSSHPTANSSASVATGTGATGGLHYGSGTGGGPVTGATMLPTMSGMLNSNSSNSAGGSSSNASSSSLRNSVVGHIGSTSGTTVPTLGSQDPHQHHLNSNAPLPPGAKGKDQALLMRQKMHLGLGVLDVQSHHGVNSVGSVSDGTNHAYNSVNNSVSGSLRDNSVNSPLYMHHSMSPSLNFTKSPIPTIVGHTNNMSIAYTCNPPFGLKATLDGGVMVANASPATPGGNASSGSSGANSSQSIVPGMGPVCGISVITSMGSNSGTLCEGPPTPTQELDLSGSALEQQQLAAAAAAATASSLQLQAAQQAQQQRKLDGTSSATLSS-----------------LQSCVSSSGQAANLRGPEISPKLAKYFRADLIAHVTNWHAEVLERQAQKCCEDTHLFGDITCTRICAELKCARSLVRSTEINATLQEQKIMYLRHQIRRIEESKTQNAFMSDDT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*** *:.** ::: . .:*: ****. .. . * ..:** * . * **.:. :.: *.*.: : : . * .:: .*:. ::..:: *:....:. : *.. . .*****:***** *****:**:*********::**:. . : .. :*** : *.. : : :* :.. . : .. *:: ..: .* ::.. *. . * .*:.* :. . *::: : : :*: :*. . .:*: ::.:: : *::* :: : .** *. :.: : . : . : :.*:.*.: .. ... :** *: . : * . . ::* . . : . . : . :: ::: :. :** ::*:: . . .:. *. . :. .::* ** :* :** ** .* *: *:**.: *::* :* : :. *:*** ***** **:***:**:*::**:**:.:*: *.**:** ", "identical_positions": 129, "similar_positions": 207, "identity": "15.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2631", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z1D3-1", "uniprot_id": "CEFIP_MOUSE", "id": "D3Z1D3-1", "name": "Cardiac-enriched FHL2-interacting protein", "aln": "-------------MMQGNKKCTDGFSDTSSIGSVLDEADREVSNLTDRAFRSLCISEDTSFHDSDLALSPDVTSQVSGTFHQETVGHANRKSGIWSQLPSQGTEHSGWAATFQQQPKYVQGEEKYPKTSPLPTPVQRRLEVPISGLRSSSKPISKVSSLIRSFDRTETQSCDSRPPPS-----------KPPALKNPPKFAHPPE--------------------------------------------SGVNFCFDSAFLTVRRVPAEVSNTHQGSHQSGRAPG-------------------------------EQESPKNPEIASHSSDSLLRTPDHVAGSFEPRYPS---------------PPLKPATAEPGRGKEWIPRRTFLHSE------------------------------------------------NSAFESWDTHQPKLRERKDIAETTPESKAP-----------------------------------------KHYEDMPLLKEPYPAESKGSPYQARANCAQEENRSPSGSQSTSGAWGARD----------------------------------------------------------------------------------PGSQLFPVEGNA--SQIDPQVKR--------------------------SKAPWR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KPKTGKGGTDGPPDALEDKKQPNRR----GLPLYSKLNPQGQLPENGVLDMPEESNDHYNPPFNISKLLTPIISTKHVLETSDTQPVEISPSP-----------------------------------------------PGQLNGYQEKESSEAQSR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DSYKSKAPSLLFNLKDVRKR-----VKSTYSPLPLLK-------------------------------------GFDEKTRGKLDSKQEP-------------------------LSNGVTLPDGLEENPPTEL--------------------------------------------LPDNVPG-------------------------------------------VLHSSTQKDPAINSRESFAVSHPTFSSPSASSQTHFCVNGEAAE---------------------------------------------------------------------------------------------------------------------------------SNSNEKEEANGESELDPSKGGGHPDCRENLPRKHLSLKLFNRE-----------------------------------SEMGPAMAEMKPHQLENGLSRS---------------------------------------------------------VSQETETERETGFQSLPLNQKFSPGP------------------------------LSPEEEDVFYSD--------------------------------------SQSDFTPCRQTKAKFSTSSSDQSFAS-----------------------------------FEDQQKVCFTE----------------GPQEDRKSHVSAGDKQRDE--TAVEKEESQQCASRNEHRGVDEQRQ-EEIQRKAQGVSGG------------------RPRKASAEDLSARGSWMGADKDTAHTHAK----------------------------------------------------------------------------------------------------DPTPLP-ASTNKHRLFPIKDN-------------------------------------------------------------------------------------TLRATPVIKPIILPLLR--------TVSSEDSLSSGHQENELPKQLWGEDAGGLSASESQEMPN-----------------------------------------------------------------------------TPLSNNDVPGTQHRCMVCEDVQE-DPVHTAAQDETSQQTRKGSFSFLPPVEEENRMKPSPDTAGEGLAQ-EKSKSADLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGVPQRIPTIALLPDDLEDSPPSLPQHTYWEEQ---------------------------------------------------------------------GFKGHFLSAPRAGPSGRRLVPSEAETS----------------------------------------------------------------------PNPSSLGESSTCSPAASSIWEEASQ---------------------------------------------------------------------AAG-EHWQRQEPPGPNPWASPGPTGLTR---------------------------------------------------------------------------------------------------------------------------------------------------------------REDMTHG-----------------------------------------------LTWEAEGSDP------SDFRALSPRGILLADAAE------------------------------KPEPPALLEKAAGKPPAVPPKTEKALRRAKKLASKRRKSDQLLEKHTEAWEGKSFTEDTQGTERRPVSPGKGPRPRFPAIRSLPPPTHRHSVSCGWEPTGRRPWGPQSLTPLPPYPATQKVLQDPQSGQYFVFDVPLQVKIKTFYDPETGKYVKVSVPS-SEEASSEPPLQDALAAPYLLYPGFRPVPVTSVMPLRCSSQLAAPTFLRQG-----SGHRPQSSQGSRLQPPPERLGESTQHASGQCPRGPSHSPEKESAEAPRLSIISTDDLEDFATEGVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q711Q0-1", "uniprot_id": "CEFIP_HUMAN", "id": "Q711Q0-1", "name": "Cardiac-enriched FHL2-interacting protein", "aln": "-------------MMQGNKKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDITRQVFGTFHQRTVGHTQRKSGIWSQLPSQGTEHSGWAATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTAS-----------KPPALKNPPKFAPLPE--------------------------------------------NSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHG-------------------------------EQESSKNPEMACHGSSSFLPAANDTATLCESKFPS---------------PHHKPVTGEPGRGK-----GTFLHSE------------------------------------------------NSAFESWNAHQPKLLERKDTAGTVPESKAP-----------------------------------------KHYGDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRD----------------------------------------------------------------------------------PGAQVFAVEGKAPSSQPDSQEKP--------------------------AQPPWR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KPKTGKKGKESLQDTLEEKTQTNQR----GPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSP-----------------------------------------------PGQLNGYQEKEPSECQSR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DSYKSKAPSLLFNLKDVRKR-----VKSTYSSSPLLK-------------------------------------VLDEKTRGKVDGKQEP-------------------------VSNGVILPNGLEESPPNELSK-----------------------------------------ERPADDPT-------------------------------------------ASHINPQKDPTADPSEPSADSYLTLSTAPTIAKAPFYVNGEAAE---------------------------------------------------------------------------------------------------------------------------------RSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRD-----------------------------------PEPGGATEKMKTHQLENGLSRS---------------------------------------------------------VSQETEPEREAGLQNTHLNQKFFPGP------------------------------LSPEEEDVFYSD--------------------------------------SQSDFMPSLKGKAKFSTSSSDQSFAS-----------------------------------FDDQQKMWFTE----------------NQREDRRKDVSAGDSQKDEKENVMRKDELQYCALSNGHACLENRSQGEALQRERESVSGG------------------RTRKASAEEANFRGSWIGENKGTTFSQAK----------------------------------------------------------------------------------------------------DLTPSPSSASNRHMLFTIKDN-------------------------------------------------------------------------------------TLRATPVIKPIMLPLLR--------TMSLEDSLSSGHKEEELPRPEWGEDPG-FCAPENQDILG-----------------------------------------------------------------------------TSTPTN-TRGTRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTP-------------------------------------------------------------------GFKSHFLSTPRAGPPGRRLVPSERANS----------------------------------------------------------------------PNPGSPGESSACSPAASNIWEESSQ---------------------------------------------------------------------APGGPELLPEEPNQASPWASSSPARVTR---------------------------------------------------------------------------------------------------------------------------------------------------------------REDLTHA-----------------------------------------------LVWEG-GSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSG------------------------RLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPS-SEGASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQSVHESGLQLDPGPHGDCTPHSAGQRPHGPPQSPGEEGVEAPGLGIISTDDLEDFATEGIS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B3A7-1", "uniprot_id": "A0A8M2B3A7_DANRE", "id": "A0A8M2B3A7-1", "name": "", "aln": "MSLLEKCHTGQRGSMQGHRKYSDGFSDTSSCGSFMDDTDREVSNLTDRAFRSLCIGEEAIYNDSEFSSSPTERHKAFAEETQQKTASEETYSYSIQKYG-ETEAQPEMASTFQHSYVDVTHQEQAFREGSLPYMNNGSNEVTWQQGRSSSRVSSLIKAFSAGECYRDSGTCDIILARDRYRDFGSESWDKSTLLSIQRELSDFSENHHNFKLGSFQSYRNNFYASEMASAVGQMDTTVLMKTSKSKLSMNSTNCFFHSEFSPFQLWEEYNKFTFESTKMSGFMSANEFPRWYDSPMYKELKDNNRVPNSLCENRRLSQRQIQDVVASQRSRSTLTHKASAIEKRCESEIASNYPPWKKNNNFVRNKPVNRPSTVSPSNERTCRPDSNLFSNSKATHEIVVESTLPSSVTPFSITQLLTPVIHLRQETETSEILQFAHTPSVSDYSSQNEADPKLQTDVQHLRDSYKSKASSLLFNLKDNRKRVKSTYSPTRFKGLEITDRNKQTSKLEGRESRFSDILVSQETAHENLSGTDARASCNSIREPSAALNTLKDYTDGFGSYDNLTLNSPQIQERVANYKSVHGSSEGSEGHSPSRDSLANVGLSTHNLSAQHKSYLTSEGQLKDLNYTFSPARPEIANMHPKAYPPTHSLPAQTSERYGQSNNLSQNDVQQRKDFGRKTWDKFDSVNERDDRFESGPFRGEIAALIEMDKQRKATAKQYSANDNYSVRKETYMQKVNEDIKLGRLSKEEAKEVREDSISPRKTSYSDSQLNTFSKHTESYGMLKKQNTTHPLKEVYGGLQSLNVTNDHVKAPEQNVSSNSMAMQKTFDQRVYAPLQDHKAQKNEELYSYQPYKYEHNKQWHMSTSEDRHTKESMWMQKKLETMEQTDAKSYNVSNTLSTTTEFVTCNGAPKPRLQDGESASSTDTSDQNNSTKQDRFSINDILAIRDNEQARRLKDNSVSMSKSENSQSQVKLDAAEKLTTTDLAKEQEQQGYKVQEVISPSPGYIRKEFHNATNISNDRKDRIMSKDTEKATTRAMSYKERGQSKQEILTSKLKAHAQKEISAIKEKGLARQGILARNTTKPSMTINNEGQEGHSNKKEITADKLNHLFQDITYSSVTQYKEQNKTQDHHLNNESPPSTEKEPPNVEDNQKFSLEMRNEKVKRIPLTVDRQNDAHPADDKVLMKETFSHVGDTIVSDMINNAQKDYQQSRISEDRQMNVTSSEDINANKESVKQSHELMSGHVTTAHKPEKCTSQNSPVLYNEKHDQKENLYGSNQSKYTEKALIKPADTTKKDFTSTEASKSTSGLNKNDLLGLERNKPRVEELNVHHKSKIDAAVEQPKIEPIKNSSEITASQLTSSSSDMKFKNGIPPAKPLMESAKSELTSNLQTITLSADVEQLVTRTYKHNSGLSSDSEASSMEITAKVKSMPTNNPGSQRIMEPETLKCVNNKNGQALMIKNNTTPENVLFNQQNNPLQVKANDSTTANQIKDNQSSLGTSKESLTQMASVRAKENCLQKDLPQDDENTKSLLRFNKEDKQALIIGNNKTKQHIMDDQQSNASQVKSPETTTANQMVDSQSKPGSDKESLKHKTSAKAKENCEQEKLQRDEDMTKSLLYFNNEDVQALAIKNIKTKENVLDNQQNSASQGKAVKTTTANQKMDSQSKLETSKESLAQMASVKAKKKSMQKELHQDDENDKVLLCFNNEDGQAIMIKNIKTKENVLDNQQNSASRGKAVEATTANQKMDSQSNLGMSKYLLPQMASIKGNENCEQKVLNQDDENTKSLLCFNNEDRQSLMIKNIKTKEKVLDSQQNSASQGKAIESTTANQKMDSRPNLGTSKYSLTQITSVKAKEHCEQKELHQDDRNTESMLCLYNEDGQAVKNIKTKDDVLVDQQNSASKGNAVETTIANQKKGSLSKLETSKESLTQMASVTAKESFEQKDLHQVDESTKSLLSFNKEDGQALLIKDSKAKQNIMDNQQSNASQEKSTPANQMVDSRSKPGSNKESLKHKTSAKAKENDHQKEPHKDKENTKNLVLFDKKELSKSQNMSRIIDSSATVSNSQQVEKRPESAMSKQKELPRPLEISKENNNHKTTKESQEKNPSNSEPKKAIDKLEPNVSSQHKVKLDEGATQKDNTKPVSTQNVESTAGVSNIIHTPSKVESAEEPMIYNICVSSKTEAASDDEPMIYTICVSSKCHIDEQQNSVKQEEESSVETEISVKDDSFRIENDRAENEPEVVRRKTEVSSNVEEKEDKIGKCELTTTMNKSNVMGRITTSYEDLLAKYGLPASDYHGHLMSKRTQEERERKEKEDTETQFSNKPIKHGITKPLTPKEKSSGDKQTHSDDSRQASSQKTSITSQPLKEAEGKIKQLQHCDIPSNNVAEKQQSSGNSIPSLGHSTSDTTLIPKDINRHVEQDRVTQNIEPSSQSRGSNIQSKEKKVEEQVRNSEKVQSMKNTGNITDDVSRKSTKKTDNESLMTKQSVMCESTRAAKSDVLKASVSNTSLAKDTAKTKLTESKIPKKTIPQAEKKLEEVEGKEKMFNQTDTLMLHPNKIHRRETFNSENQKSIHEDKQQDSTMALKKESVSHKDTQTLQKNGKENLEVKRSQEKLQVELNKSHEITNQMKMVSKDTTHVNNYKDQVSSIGEDVCTVVKHNQASFEAPKIHLEDIKVSTEEVSSNKEFMVGHKNQHEVIKRKTLQGKKVTVVAEHVGEKDFAELKKLPIKTLAAQNEPKTVDIMKGLCETAPKPLKRDCPSESEKPEINQQDALVQSQHIKVCDNKQPALNSEERKIEQPVLSKNGQKDGNLKVRNENRSSLEGKQVKHIEATETKQAHQPNTNQNQPGRGLEPEKERSASYELEHAQIYQKDAKKEGMLSKNEATQRNKKVTRPEISAIADYARLKVIAAEDDTKELDIFPKTDFYNSYDQPASRISKDSHRKVSGDIWEDSKREAILREKGQNLKQTPSLAQKHNPSTNIAEATPVSLVASGSQGRAASTQSRTPAIHRKSNTKQTLEQTKTGESYKTYQSRNPQGDNIAALQAESTINRSRQPAHDKRMEKTSFSHSGRQVLGNVKQADNQINMASPPEEEMEELQYYTVNALDIEPKPNYTPEPPHESPKIYQNKLEEDKKEDSLSLQSLTEYGKANMTGPRSNSSSPAMGKPTMFRVKDNTIRPSSVTKTVKPRFHRSFSDDLRIGSPKEHLSGSEKEDETHPKESANLPLLHEPAIVTQPLQKVKETLHNNMSIADYSTNKLKSYQRRSQHFEEEETRSVISTMSEDLENCTARPIDLADLSMAFMPKNEFYRDSYRRPASACYERPDSVCYERPESACSDIRSLGKPPAVPPKSEKALRRAQRLTTRRLKKSESPKLAPENQE-QPEPKSISNISSVPSSPSDVP-SSHQEVHASPPLSQYDTQPNYSPP-------AHSIVAQPFPMTQRKLLQDPNSGQYFMVDVPLPVKTKTFYDPETGKYVQLNVRQRSQGALTQPAQVEMLNAPYMLYRGFLPMAASSLSPLRSSSEMSTPAALTVHRDMLETGSEAWTQN-VHHSRDSQQYPETQYGSHEQIHNPALYAENNVDDNDRHRDIITMSELEDFAMEST-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***::* :*.***:** **.:*::*****.***********.*:: ::** :: ** :. . *.... : * .: : :. *:***: * :*: : .. * : **. . ***.: * :.:: . :: *: . . *.. *. ::: .* ...* *.* * ..: . *.:.: .* . .*.. :: : :. .:: .. *.. .* * :* * .*.. : .:: .. * :.* : :*** : :***. .:: * : :*. : . : :. ... :* . . : :*. * * :: :..: . .* : : . *:* **: . . . *: :::...:: . * : * * : ::. :.:. . *.: : :: :: **. :*. : . . :*** ..:*:.: :** * :.: :. .*: ..:*:* *. :*. :*.*: .*:* :: : :.*:*. * ..**: .. * *.. .** * : * : .. : : .. . * ::: .: :: : .: .: ::: :.: :: .: . . : :* :. .* : : .. * * ..:* :. *. **:....: .::. ***: . * ..*. :*.: * *.: .. : ::::: ::.:** . :::**. * . :*. : ..** .:.*. ...* : :.: : . : . **.. *. : * *: . : : . :*..: :..* : :. : :. * *::: : .*: : * ** :** .:. :: .:. * * : : :: . * .: . . : * : : :.. . *.... . . : : * . . :. : .*.. . *: : . * * . . *.: * . . .. . .** * *.: .: :*.* ...: .:..***::.: . . .:* . * . : :.* :** ** :* : . .*:. :.* * : : * .. :: .********:*******::*:::* *..: : * * :. .:. . . * .* . * . ::: ** : .: . * .:*:.. * : :*:****:**:**:.*:** ** ************::.: . *: * .:*. : * ***:** ** *:..::: ***.**::::*: * : .. : : . . : : * . . : : . : .**: .:***** *. ", "identical_positions": 277, "similar_positions": 533, "identity": "7.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2635", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O75365-1", "uniprot_id": "TP4A3_HUMAN", "id": "O75365-1", "name": "Protein tyrosine phosphatase type IVA 3", "aln": "MARMN-----RPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FA22-1", "uniprot_id": "E7FA22_DANRE", "id": "E7FA22-1", "name": "", "aln": "MAWLN-----GLYPVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDWPFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEEAIHLIRLKRHGAFNSKQLTYLEKYRSKKRLRFKDPFKHRSKCWLM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O61722-1", "uniprot_id": "PRL1_DROME", "id": "O61722-1", "name": "PRL-1 phosphatase", "aln": "MSITMRQKDLRPAPALIEYKGMKFLITDRPSDITINHYIMELKKNNVNTVVRVCEPSYNTDELETQGITVKDLAFEDGTFPPQQVVDEWFEVLKDKYQQNPEACVAVHCVAGLGRAPVLVALALIELGLKYEAAVEMIRDKRRGAINAKQLSFLEKYKPKARLKHKN--GHKNSCSVQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *. : *: *:*:**..*:: *:. :* :**: ...******* :*:. **..**** * .*:**: ** ::*::*:.::* .: : * .******************:**** *:*** *:.:** **:**:*:***::****:.* **:.*: *:. * : ", "identical_positions": 83, "similar_positions": 56, "identity": "46.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2637", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P788-1", "uniprot_id": "ATF5_RAT", "id": "Q6P788-1", "name": "Cyclic AMP-dependent transcription factor ATF-5", "aln": "-----------------------------MSLLATLGLELDRALLP---ASGLGWLVDYGKLPLAPAPLGPYEVLGGALEGGLPGGGEPLAGDGFSDWMTER------------VDFTALLPLEAPLPPGTLPPPS-------------------------------------------------------PAPPDLEAMASLLKKE------------LEQMEDFFLDAPLLPPP-----------------------------SPPPPPPP--APSLPLPLP---------LPTFDLPQPPTLDTL--DLLAVYCRS----EAGPGDSG---------LTTLPVPQQPPPLAPLPSLSRPAPYPSPASTR--GDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELRERAESVEREIQYVKDLLIEVYKARSQRTRSA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70191-1", "uniprot_id": "ATF5_MOUSE", "id": "O70191-1", "name": "Cyclic AMP-dependent transcription factor ATF-5", "aln": "-----------------------------MSLLATLGLELDRALLP---ASGLGWLVDYGKLPLAPAPLGPYEVLGGALEGGLPGGGEPLAGDGFSDWMTER------------VDFTALLPLEAPLPPGTLPPPS-------------------------------------------------------PAPPDLEAMASLLKKE------------LEQMEDFFLDAPLLPPP-----------------------------SPPPPPPPAAAPSLPLPLP---------LPTFDLPQPPTLDTL--DLLAVYCRS----EAGPGDSG---------LSTLPVPQQPPPLAPLPSPARPAPYPSPASTR--GDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELRERAESVEREIQYVKDLLIEVYKARSQRTRST---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2D1-1", "uniprot_id": "ATF5_HUMAN", "id": "Q9Y2D1-1", "name": "Cyclic AMP-dependent transcription factor ATF-5", "aln": "-----------------------------MSLLATLGLELDRALLP---ASGLGWLVDYGKLPPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTER------------VDFTALLPLEPPLPPGTLPQPS-------------------------------------------------------PTPPDLEAMASLLKKE------------LEQMEDFFLDAPPLPPP-----------------------------SPPPLPPPPLPPAPSLPLS---------LPSFDLPQPPVLDTL--DLLAIYCRN----EAGQEEVG---------MPPLPPPQQPPPPSP-PQPSRLAPYPHPATTR--GDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELKERAESVEREIQYVKDLLIEVYKARSQRTRSC---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P756-1", "uniprot_id": "A0A8M9P756_DANRE", "id": "A0A8M9P756-1", "name": "", "aln": "MAYNWMTKTFDTYPNSTSTESSPGSSIPPSPLEHDVQMPSDLEVMTNLLKEELAQLEDYYLYESAPMKLEKWQKCDKSLQAMATQSYYQLPCASYNVNQSETNPRLVSLA-AGELDLRGFCGGSVNRPKMSRPAPYSYIRTHCNSQRISSNGCKDVEVFEKETWTFKGTHSGYAELAFDQCSVDKSFGKNHGSAKKVRECAILLKEEEKSCFSEDVFYRAEMMRSYDLAGSLEPHHRRESQCHGMKMLGHDGIAMPILQCAENESCPPPYKQSDVAECYFHQITANLEPYHGFMNEIDQPIRTDIQNN--DYLHHECLGDQSFECLSGDSV---------GSSLELPVQKPLQRSRESQCVFKPDVKVGVERNHGERKQKKRDQNKSAAHRYRQRKRAEQDCLEEELHGLEGRNRELRDKAESVEREIQYVKDLLIEVYKARSQRLKEDSSA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VID3-1", "uniprot_id": "Q9VID3_DROME", "id": "Q9VID3-1", "name": "", "aln": "-----MDATFHQTMESLQLPKELYWDLKMEPQSPTSVLGSDLFPLTD--SNDTEWLYDDNFANGITLIGDDEALTLEEVASLQLLSDEEMVVEIFDLKDEECLLDQKATLNCIDYDSNSFQPNINVITQAIVPANKVQFG-----------------------------------------ASSDAASLPSAADYQLNDGPSLILQQLTPPQS------PPQFDAYKQAGDAQPKP---------VLVKAEQKVQCYTPDVTHAASATPFNFTNWVGGSEIARENQLVDDIVNMRAKELELSTNWQQLNEDCESQASSSLDSRSTGSGVCSSIADADEDWVPELISSSSSPAPTTIEQSASQPKKRTRTYGRGVEDRKIRKKEQNKNAATRYRQKKKLEMENVLGEEHVLSKENEQLRRTLQERHNEMRYLRQLIREFYHERKR--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * :. . * * . : . . : :. * * .: . * : .:. . *: :: : : . * ...* . : : . : * . . . . * . . * . . . * :** :*::***.** ****:*: * : : * : *. .*.:*: :. ..*::*:::*: *.*: *.: ", "identical_positions": 37, "similar_positions": 72, "identity": "8.19%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2638", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TDQ1-1", "uniprot_id": "STT3B_MOUSE", "id": "Q3TDQ1-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "aln": "MAEP-SAPESKHKSSLNSSPWSGLMALGNSRHGHHGPGTQSASSAA---APKPGPPAGLSGGLSQPAGWQSLLSFTILFLAWLAGFSSRLFAVIRFESIIHEFDPWFNYRSTHHLASHGFYEFLNWFDERAWYPLGRIVGGTVYPGLMITAGLIHWILNTLNITVHIRDVCVFLAPTFSGLTSISTFLLTRELWNQGAGLLAACFIAIVPGYISRSVAGSFDNEGIAIFALQFTYYLWVKSVKTGSVFWTMCCCLSYFYMVSAWGGYVFIINLIPLHVFVLLLMQRYSKRVYIAYSTFYIVGLILSMQIPFVGFQPIRTSEHMAAAGVFALLQAYAFLQYLRDRLTKQEFQTLFFLGVSLAAGAVFLSVIYLTYTGYIAPWSGRFYSLWDTGYAKIHIPIIASVSEHQPTTWVSFFFDLHILVCTFPAGLWFCIKNINDERVFVALYAISAVYFAGVMVRLMLTLTPVVCMLSAIAFSNVFEHYLGDDMKRENPPVEDSSDEDDKRNPGNLYDKAGKVRKHVTEQEKPEEGLGPNIKSIVTMLMLMLLMMFAVHCTWVTSNAYSSPSVVLASYNHDGTRNILDDFREAYFWLRQNTDEHARVMSWWDYGYQIAGMANRTTLVDNNTWNNSHIALVGKAMSSNETAAYKIMRSLDVDYVLVIFGGVIGYSGDDINKFLWMVRIAEGEHPKDIREGDYFTQQGEFRVDKAGSPTLLNCLMYKMSYYRFGEMQLDFRTPPGFDRTRNAEIGNKDIKFKHLEEAFTSEHWLVRIYKVKAPDNRETLGHKPRVTNIVPKQKYLSKKTTKRKRGYVKNKLVFKKGKKTSKKTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TCJ2-1", "uniprot_id": "STT3B_HUMAN", "id": "Q8TCJ2-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "aln": "MAEP-SAPESKHKSSLNSSPWSGLMALGNSRHGHHGPGAQCAHKAAGGAAPPKPAPAGLSGGLSQPAGWQSLLSFTILFLAWLAGFSSRLFAVIRFESIIHEFDPWFNYRSTHHLASHGFYEFLNWFDERAWYPLGRIVGGTVYPGLMITAGLIHWILNTLNITVHIRDVCVFLAPTFSGLTSISTFLLTRELWNQGAGLLAACFIAIVPGYISRSVAGSFDNEGIAIFALQFTYYLWVKSVKTGSVFWTMCCCLSYFYMVSAWGGYVFIINLIPLHVFVLLLMQRYSKRVYIAYSTFYIVGLILSMQIPFVGFQPIRTSEHMAAAGVFALLQAYAFLQYLRDRLTKQEFQTLFFLGVSLAAGAVFLSVIYLTYTGYIAPWSGRFYSLWDTGYAKIHIPIIASVSEHQPTTWVSFFFDLHILVCTFPAGLWFCIKNINDERVFVALYAISAVYFAGVMVRLMLTLTPVVCMLSAIAFSNVFEHYLGDDMKRENPPVEDSSDEDDKRNQGNLYDKAGKVRKHATEQEKTEEGLGPNIKSIVTMLMLMLLMMFAVHCTWVTSNAYSSPSVVLASYNHDGTRNILDDFREAYFWLRQNTDEHARVMSWWDYGYQIAGMANRTTLVDNNTWNNSHIALVGKAMSSNETAAYKIMRTLDVDYVLVIFGGVIGYSGDDINKFLWMVRIAEGEHPKDIRESDYFTPQGEFRVDKAGSPTLLNCLMYKMSYYRFGEMQLDFRTPPGFDRTRNAEIGNKDIKFKHLEEAFTSEHWLVRIYKVKAPDNRETLDHKPRVTNIFPKQKYLSKKTTKRKRGYIKNKLVFKKGKKISKKTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EZE2-1", "uniprot_id": "E7EZE2_DANRE", "id": "E7EZE2-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "aln": "MAEHHTASDCKHKASSN---------AGGSVSGNGRPNSPAGCSGG-----------GLSGGLTQPAGWQSLLSFTILFLAWLAGFSSRLFAVIRFESIIHEFDPWFNYRSTHHLTTNGFYEFLNWFDERAWYPLGRIVGGTVYPGLMVTAGLIHYVLNLLHVTVHIRDVCVFLAPVFSGLTAISTFLLTRELWNQGAGLLAACFIAIVPGYISRSVAGSFDNEGIAIFALQFTYYLWVKSVKTGSVFWAIGCCLSYFYMVSAWGGYVFIINLIPLHVFVLLLMQRYSRRLYIAYSTFYIVGLVLSMQIPFVGFQPIRTSEHMAAAGVFALLQAYAFLQYLKDRLTRQEFQTLFFLGVSLAAGVVFLTVIYLTYTGYIAPWSGRFYSLWDTGYAKIHIPIIASVSEHQPTTWVSFFFDLHILVCTFPAGLWFCIKNINDERVFVALYAISAVYFAGVMVRLMLTLTPVVCMLSAIAFSSVFEHYLGDDLKRENPPAEDSSDEDDKRNQGNLYDKAGKVRKHVSEQDRPEEGLGPNIRSIVTMLMLMLLMMFAVHCTWVTSNAYSSPSVVLASYNHDGSRNILDDFREAYYWLRQNTDEHARVMSWWDYGYQIAGMANRTTLVDNNTWNNSHIALVGKAMSSNESAAYEIMKSLDVDYVLIIFGGVIGYSGDDINKFLWMVRIAEGEHPKDIRESDYFTPQGEFRVDKAGSPTLLNCLMYKMSYYRFGEMQLDFRTPPGFDRTRNAEIGNKDIRLKHLEEAFTSEHWLVRIYRVKKQENRQTLDHKLR--NIAAKQKYTSKKTAKRKRGHIKNKLALKKGKKLNKKSV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** :*.:.***:* * *.* *: *.: .. ... ******:***************************************************:::******************************:******::** *::*************.*****:******************************************************************:: ************************************:*:************:*************************************:****:****************.***:**************************************************************************************************************.*********:******.*********** *************.:**::.********:****************************************:***********:*****************************************************:***:**::*******:*********************************.**** *****************************************************::*****************:** :**:**.** * ** .**** ****:*****::****.:***** .**:*", "identical_positions": 720, "similar_positions": 65, "identity": "87.06%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2643", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q76K24-1", "uniprot_id": "ANR46_RAT", "id": "Q76K24-1", "name": "Ankyrin repeat domain-containing protein 46", "aln": "MSYVFVNDSSQTNVPLLQACIDGDFTYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADPLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGTHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLILVIALLSLGIAYYVSGVLPFVDNQPGLVH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BTZ5-1", "uniprot_id": "ANR46_MOUSE", "id": "Q8BTZ5-1", "name": "Ankyrin repeat domain-containing protein 46", "aln": "MSYVFVNDSSQTNVPLLQACIDGDFTYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADPLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGAHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLILVIALLSLGIAYYVSGVLPFVDNQPELVH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86W74-2", "uniprot_id": "ANR46_HUMAN", "id": "Q86W74-2", "name": "Ankyrin repeat domain-containing protein 46", "aln": "MSYVFVNDSSQTNVPLLQACIDGDFNYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGTHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLIFVIALLSLGIAYYVSGVLPFVENQPELVH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F3W1-1", "uniprot_id": "E7F3W1_DANRE", "id": "E7F3W1-1", "name": "", "aln": "MSYVFVNDSLQATVPLLQACIDGDLAHTKRLLESGFDPNMRDCRGRTGLHLAAARGNVEICSLLHKFGADLLATDSQGNTALHMCGHVDTIQFLVSNGLKIDICNHNGATPLVLAKRRGVNKDALHLLEGLEEQEVKGFNRSSHSSLEKMHMAENESAMESHSLLNPHLHHSDGVLSSFKTTWQEFVEDLGFWRVLLLLLVIALLSLGIAYYVSGVLPFASNQLELVH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********* *:.***********: ::***********:**.***************:**.******** **** *******:**********************:****************.::***.***********.:**.**.*: **.************:*::.:******:******************::*******************..** ***", "identical_positions": 190, "similar_positions": 31, "identity": "83.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2644", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3X946-1", "uniprot_id": "G3X946_MOUSE", "id": "G3X946-1", "name": "Flavin-containing monooxygenase", "aln": "---MGVKRIAVIGAGVSGLGAIKCCLEEG--LEPTCFEKKSDIGGLWKYEEIPKSGNLGIYKSLTCNTSKEMTAFSDYPIPDHYPNYMHHSKMMEYLRMYARHFGLMK---HIQFQTNVCNIKKRPDFSSSGQWDVVVET-EEMQKTYIFDGIMVCSGHYTEKYFPLQDFEGISKFQG--SYLHTWEYKHPDNFVGKRVAVIGLGNSGADVAGEISRVADQVFLSTRQGAWIWNRVWDHGEPMDTTVFTRYNRAVQKICPRYIINRQMEKKLNGRFNHANYGLLPTHRILEQRTVLSDDLPNRIIIGKVKIKPNVKEFTSTSAIFEDGT-KENIDVVIFATGYKLSFPFLSDDS-GVLDNQYSMFKYVFPPELEKPTLAFIGILQPAGAILPTSELQSRWVVHVFKGIKKLPSRRAMIADINRKNHQIMAK------GSKKILQDHRRVTFVDYMDEIASEIGVKPNLLSLLLWDTKLAKEVFCGPCTSYQYRLQGPGKWDGARAAILTQRERMLKPLRTRVVKQS--HLSHLSWVKS-ACVVVFFFISVVVIMHITSH-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZBP5-1", "uniprot_id": "D3ZBP5_RAT", "id": "D3ZBP5-1", "name": "Flavin-containing monooxygenase", "aln": "---MGVKKVAVIGAGVSGLGAIKCCLDEG--LEPTCFEKRSDIGGLWKYEEISKSGNLGIYKSLTCNTSKEMTAFSDYPIPDHYPNYMHNSKMMEYLRMYARHFGLLK---HIQFQTKVCSIKKRPDFSSSGQWDVVVET-GETQKTYIFDGIMVCSGHYTEKHFPLQDFEGISKFQG--SCLHSWEYKHPNSFSGKRVVVIGIGNSGADVAGEISRVADQVFLSTRRGAWVWSRVWDHGNPMDASLFTRYNRAVQKFCPRYLINRQMEKKLNARFNHANFGLLPQHRILDHRTVFSDDLPSHIITGKVKIKTNVKTFTSTSAVFEDGT-EENIDVVIFATGYKLAFPFLSDDS-GILDSQYSMFKYVFPPELEKPTLAFIGIVQPAGAIIPTSELQSRWVVRVFTGLQKLPPKKAMMADIYRK-HQADKD------AIKNLKDSSRRVQFIDYMDEIASEIGVKPNLLSLLLWDTKLAKEIFYGPCTSYQYRLQGPGKWAGARAAILTQRERILKPLRTRVVKHSRASLSHLFWVKS-VCVVSFFFISVLVIMHLTSV-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A6T0-1", "uniprot_id": "D4A6T0_RAT", "id": "D4A6T0-1", "name": "Flavin-containing monooxygenase", "aln": "---MEVKQIAIIGAGVSGLGAIKCCLEEG--LEPTCFEKSNDIGGLWRYEETTE--RPGIYKSLTCNTSKEMTAFSDYPIPDHYPNYMHNSKMMEYLRMYARHFGLMK---HIQFQTRVCRVRKRPDFSSSGQWDVVVEV-DGKQKTYVFDGVMVCSGHSTEKCLPLQDFAGISKFQG--KYLHSWEYRHPDSFVGKRVVVIGIGNSGADVAGEISHVAEQVFLSTRRGAWIWNRVWDNGNPLDTTLFTRYNRTIQKFYPTFLINRWAENKLNARFNHANYGLQAKHRFLSHQSIFSDNLPNHIITGRVLVKPNVKEFTPTSAIFEDGS-EEIVDNVVFATGYTFSFPFLDDSS-KILDSEHTMFKFVFPPQLEMPTLAFIGILQPVGATIPTSELQSRWVTRVFTGLQKLPSQSNMMADINKRKRKMEKE------FVKSPRGIHR-VQYIDYMDEIASELGVKPNLLSLFLWDTKLAKEIFWGPCTPYQYRLQGPGKWAGARVAILTQRDRILKPLKTRVLKNCETSSSSLFWVRY-ICAVIVLFVPVLLILLVIYQ-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZD07-1", "uniprot_id": "D3ZD07_RAT", "id": "D3ZD07-1", "name": "Flavin-containing monooxygenase", "aln": "---MAKKRIAVIGAGISGLGAIKCCLDED--LEPTCFERSDDIGGLWKFQKNPSEKMPSIYKSVTINTSKEMMCFSDFPIPDHFPNYMHNCKLMDYFRMYAEHFGLLD---HIRFKTTVRSVRKRPDFSVQGQWDVIVEA-DGKQESLVFDGILVCSGHHTDPHLPLKSFPGIEKFEG--CYFHSREYKSPEDYVGKRIIVVGIGNSGVDIAVELGRVAKQVFLSTRRGSWILHRVWNNGYPMDSSFFTRFNSFLQKLLSTEAVNKYLEKMMNSRFNHAHYGLQPQHRPLSQHPTVSDDLPNHIISGKVQVKPNVKEFRGTDVVFDDGTVEEKIDVVIFATGYSFSFPFLEDLI-AVTDNEVSLYKLMFPPDLEKPTLAVIGLIQPLGIVLPISELQSRWAVRVFKGLSKLPSVKIMNADMAQRKKAMAKR------YVKTVRHTIQ-VDHIEYMDEIAALAGVKPNLLLLFLSDPLLAMEVFFGPCTPYQYRLQGPGKWDGARRAILTQRERIIKPLKTRITSEKSHSAPGLFWIKMTLFGLAFLVISLIYFSYICYEKRK----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AA53ECJ5-1", "uniprot_id": "A0AA53ECJ5_DANRE", "id": "A0AA53ECJ5-1", "name": "Flavin-containing monooxygenase", "aln": "----MVKRVAVIGAGSSGLAAIKCCLDEG--LEPVCFESSDDIGGLWRFREKPETDRCSIYHSLTVNTSKEMMCYSDFPVPDNFPNFMHNSLIVQYYRLYAEHFNLFE---HIHFQTTVRSVRQRPDFSVSGQWEVVTADRDGQVETHMFDGVLVCVGHYTQPIKPLSEFPGIDTFPG--TVIHSWEYKKPDQYIGKKVLIIGIGNSGGDIAVELSRTCEKTFLSTRKGSWVIGRMVEKGLPLDMMNISRVQDLMHCLIPRALVNWIGERSLNQRHDHKLYGLQPKHRILDHRPVINDDLPGRILVGELVLKPNVQTFHGSTVVFDDGSIEEKIDAVILCTGYDYKFPFLPDSLNSSADGGMKLYRRIFPPSLERPTLAIIGLLQTRGPIMPAAELQARWATRVIKGLNHLPSAEKMSKRIEKDIKPYLKS------HPCPKLASLQ-VDYIPYLDSIAKEVGACPNIAWLLMTDPALGLRVFLGPCTPYQFRLSGPGHWKGARQAILTQWERVAKPMKTRPIPEPS-SFSLLFWLGLSGGGAVILAIIALQKKIPLFMGIS----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8K2I3-1", "uniprot_id": "FMO2_MOUSE", "id": "Q8K2I3-1", "name": "Dimethylaniline monooxygenase [N-oxide-forming] 2", "aln": "----MAKKVVVIGAGVSGLISLKCCVDEG--LEPTCFERTEDIGGLWRFKENVEDGRASIYRSVITNTSKEMSCFSDFPMPEDFPNFLHNSKLLEYFRIFAKKFDLLK---YIQFQTTVISVKKRPDFASSGQWEVYTQS-NGKEQRTVFDAVMVCSGHHIQPHLPLKSFPGIERFRG--QYFHSREYKHPVGFEGKRILVVGIGNSAADIASELSKTAAQVFVSTRHGSWVMSRISEDGYPWDMVFHTRFSSMLRNVLPRTVVKWMMEQQMNRWFNHENYGLVPQNKYLMKEPVLNDDLPSRLLYGAIKVKTRVKELTETAVVFEDGTVEEDVDIIVFATGYTFSFSFLEDSLVKVEDNRVSLYKAMFPPHLEKPTLACIGLIQPLGSIFPTVELQARWATRVFKGLCSLPSETTMMADIVERNEKRVN-------LFGKSQSQILQTNYVDYLDELALEIGAKPDFVSLFFKDPKLAVKLYFGPCNSYQYRLVGPGQWEGARNAILTQKQRILKPLKTRTLQSSDSAP---VSFLLKILGLLAVVLAFFFQLQGF---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IRI9-1", "uniprot_id": "FMO2_RAT", "id": "Q6IRI9-1", "name": "Dimethylaniline monooxygenase [N-oxide-forming] 2", "aln": "----MVKKVAVIGAGVSGLISLKGCVDEG--LEPTCFERTEDIGGLWRFKENVEDGRASIYHSVITNTSKEMSCFSDFPMPEDFPNFLHNSKLLEYFRIFAKKFDLLK---YIQFQTTVISVKKRPDFASSGQWDVYVQS-NGKEQRAVFDAVMVCSGHHIQPHLPLKSFPGIERFQG--QYFHSRQYKHPVGYEGKRILVVGIGNSAADIASELSKRAAQVFVSTRHGSWVLSRISEDGYPWDMVFHTRFSSMLRNVLPRTVVKWMMERQMNRWFNHENYGLVPQNKYLMKEPVLNDDLPSRLLYGAIKVKTRVKELTETAVVFEDGTVEEDVDVIVFATGYTFSFPFLEDSLVKVEDNKVSLYKAMFPPHLEKPTLACIGLIQPLGSIFPTVELQARWATRVFKGVCRLPSETTMMADIAERNEKRID-------LFGKSQSQILQTNYIDYLDELALEIGAKPDFISLLFKDPKLAVKLYFGPCNSYQYRLVGPGQWEGARNAILTQKQRILKPLKTRTLQTSASAP---VSFLIKVLGLLAIVLAFFFKLHGF---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99518-1", "uniprot_id": "FMO2_HUMAN", "id": "Q99518-1", "name": "Flavin-containing monooxygenase 2", "aln": "----MAKKVAVIGAGVSGLISLKCCVDEG--LEPTCFERTEDIGGVWRFKENVEDGRASIYQSVVTNTSKEMSCFSDFPMPEDFPNFLHNSKLLEYFRIFAKKFDLLK---YIQFQTTVLSVRKCPDFSSSGQWKVVTQS-NGKEQSAVFDAVMVCSGHHILPHIPLKSFPGMERFKG--QYFHSRQYKHPDGFEGKRILVIGMGNSGSDIAVELSKNAAQVFISTRHGTWVMSRISEDGYPWDSVFHTRFRSMLRNVLPRTAVKWMIEQQMNRWFNHENYGLEPQNKYIMKEPVLNDDVPSRLLCGAIKVKSTVKELTETSAIFEDGTVEENIDVIIFATGYSFSFPFLEDSLVKVENNMVSLYKYIFPAHLDKSTLACIGLIQPLGSIFPTAELQARWVTRVFKGLCSLPSERTMMMDIIKRNEKRID-------LFGESQSQTLQTNYVDYLDELALEIGAKPDFCSLLFKDPKLAVRLYFGPCNSYQYRLVGPGQWEGARNAIFTQKQRILKPLKTRALKDSSNFS---VSFLLKILGLLAVVVAFFCQLQWS---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P50285-1", "uniprot_id": "FMO1_MOUSE", "id": "P50285-1", "name": "Flavin-containing monooxygenase 1", "aln": "----MVKRVAIVGAGVSGLASIKCCLEEG--LEPTCFERSSDLGGLWRFTEHVEEGRASLYKSVVSNSSREMSCYPDFPFPEDYPNFVPNSLFLEYLKLYSTQFNLQR---CIYFNTKVCSITKRPDFAVSGQWEVVTVT-NGKQNSAIFDAVMVCTGFLTNPHLPLDSFPGILTFKG--EYFHSRQYKHPDIFKDKRVLVVGMGNSGTDIAVEASHLAKKVFLSTTGGAWVISRVFDSGYPWDMIFMTRFQNMLRNLLPTPIVSWLISKKMNSWFNHVNYGVAPEDRTQLREPVLNDELPGRIITGKVFIKPSIKEVKENSVVFNNTPKEEPIDIIVFATGYTFAFPFLDESVVKVEDGQASLYKYIFPAHLPKPTLAVIGLIKPLGSMVPTGETQARWVVQVLKGATTLPPPSVMMEEVNERKKNKHS-------GFGLCYCKALQTDYITYIDDLLTSINAKPDLRAMLLTDPRLALSIFFGPCTPYHFRLTGPGKWEGARKAILTQWDRTVKVTKTRTIQES--PS--SFETLLKLFSFLALLIAVFLIFL-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36365-1", "uniprot_id": "FMO1_RAT", "id": "P36365-1", "name": "Flavin-containing monooxygenase 1", "aln": "----MVKRVAIVGAGVSGLASIKCCLEEG--LEPTCFERSCDLGGLWRFTEHVEEGRASLYNSVVSNSSKEMSCYSDFPFPEDYPNFVPNSLFLEYLQLYATQFNLLR---CIYFNTKVCSITKRPDFAVSGQWEVVTVC-QGKQSSDTFDAVMVCTGFLTNPHLPLDSFPGIQTFKG--QYFHSRQYKHPDVFKDKRVLVVGMGNSGTDIAVEASHLAKKVFLSTTGGAWVISRVFDSGYPWDMIFMTRFQNMLRNLLPTPVVSWLISKKMNSWFNHVNYGVAPEDRTQLREPVLNDELPGRIITGKVLIKPSIKEVKENSVVFNNTPKEEPIDVIVFATGYSFAFPFLDESIVKVEDGQASLYKYIFPAHLPKPTLAVIGLIKPLGSMIPTGETQARWVVQVLKGATTLPPPSVMMKEVNERKKNKHS-------GFGLCYCKALQSDYITYIDDLLTSINAKPDLRAMLLTDPRLALSIFFGPCTPYHFRLTGPGKWEGARKAILTQWDRTVNVTKTRTVQET--PS--TFETLLKLFSFLALLVAVFFIFL-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01740-1", "uniprot_id": "FMO1_HUMAN", "id": "Q01740-1", "name": "Flavin-containing monooxygenase 1", "aln": "----MAKRVAIVGAGVSGLASIKCCLEEG--LEPTCFERSDDLGGLWRFTEHVEEGRASLYKSVVSNSCKEMSCYSDFPFPEDYPNYVPNSQFLEYLKMYANHFDLLK---HIQFKTKVCSVTKCSDSAVSGQWEVVTMH-EEKQESAIFDAVMVCTGFLTNPYLPLDSFPGINAFKG--QYFHSRQYKHPDIFKDKRVLVIGMGNSGTDIAVEASHLAEKVFLSTTGGGWVISRIFDSGYPWDMVFMTRFQNMLRNSLPTPIVTWLMERKINNWLNHANYGLIPEDRTQLKEFVLNDELPGRIITGKVFIRPSIKEVKENSVIFNNTSKEEPIDIIVFATGYTFAFPFLDESVVKVEDGQASLYKYIFPAHLQKPTLAIIGLIKPLGSMIPTGETQARWAVRVLKGVNKLPPPSVMIEEINARKENKPS-------WFGLCYCKALQSDYITYIDELLTYINAKPNLFSMLLTDPHLALTVFFGPCSPYQFRLTGPGKWEGARNAIMTQWDRTFKVIKARVVQES--PS--PFESFLKVFSFLALLVAIFLIFL-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "J3QMN6-1", "uniprot_id": "J3QMN6_MOUSE", "id": "J3QMN6-1", "name": "Flavin-containing monooxygenase", "aln": "----MGKKVAIVGAGVSGLAAIRCCLEEG--LDPICFERSIDVGGLWKFSSHAEEGRASIYQSVFTNSSKEMMCFPDFPYPDDFPNYMHHSKLQEYITSFAQKKGLLR---YIQFETLVSSIKKCSSFLTTGQWVVVTEK-EGKQESVLFDAVMICSGHHVYPNMPTDSFPGLEHFRG--KCLHSRDYKGPGAFQGKKVLVIGLGNSASDIAVELSRLATQVIISTRSGSWIMSRVWNDGYPWDMVYVTRFTSFLRNILPSFVSDWLYIKKMNTWFKHENYGLMPLNGPLRKEPVFNDELPSRILCGMVTIKPIVTKFTETSAVFEDGTVFEAIDCVIFATGYGYAYPFLDDSIIKSRNNEVTLYKGIFPPQLEKPTMAVIGLVQSLGAAIPTADLQARWAAKVFTNTCVLPTTNEMMDDIDEKMGKKLK-------WFGQS--HTLQTDYITYMDELSSFIGAKPNIPWLFLTDPQLALEVYFGPCSPYQFRLMGPGKWDGARNAILTQWKRTVKPTRTRAVGEAQRPR--HLYDLLRMLFFPVFFLAVLLTFY-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R553-1", "uniprot_id": "M0R553_RAT", "id": "M0R553-1", "name": "Flavin-containing monooxygenase", "aln": "----MGKKVAIVGAGVSGLAAIRCCLEEG--LEPICFERSNDVGGLWKFSSHVEEGRASIYQSVFTNSSKEMMCFPDFPYPDDFPNYMHHSKLQEYIKSFAQKKDLLR---YIQFETLVSSIKKCSSFLTTGQWVVVTEK-DGKQESVLFDAVMICSGHHVYPNMPTDSFPGLEHFQG--KCMHSRDYKGPGDFQGKKVLVIGLGNSASDIAVEVSRLATQVIISTRSGSWVMSRVWNDGYPWDMVYVTRFASFLRNILPSFVSDWLYVKKMNTWFKHENYGLMPLNGPLRKEPVFNDELPARILCGTVSIKPIVTKFTETSAVFEDGTVFEAIDCVIFATGYGYAYPFLEDSIIKSRNNEVTLYKGIFPPQLEKPTMAVIGLVQSLGAAIPTADLQARWAAKVFTNACVLPTTNEMMDDIDEKMGKKLK-------WFGQS--HTLQTDYITYMDELSSFIGAKPNIPWLFVTDPQLALEVYFGPCSPYQFRLMGPGKWDGARSAILTQWKRTVKPTRTRAVGEAQRPC--HLYDLLQMLFFPVFFLAVLLTFY-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60774-1", "uniprot_id": "FMO6_HUMAN", "id": "O60774-1", "name": "Putative dimethylaniline monooxygenase [N-oxide-forming] 6", "aln": "----MSKRVGIIGAGVSGLAAIWCCLEEG--LEPTCFERSDDVGGLWKFSDHTEEGRASIYQSVFTNSSKEMMCFPDFPYPDDYPNYIHHSKLQEYIKTYAQKKDLLR---YIQFETLVSGIKKCPSFLVTGQWVVVTEK-DGKQESTIFDAVMICSGHHVYPNLPTDSFPGLDQFRG--NYLHSRDYKNPEAFKGKRVLVIGLGNSGSDIAVELSRLATQVIISTRSASWVMSRVWDDGYPWDMMYVTRFASFLRNVLPSFISDWLYVQKMNTWFKHENYGLMPLNGSLRKEPVFNDELPSRILCGTLSIKPSVKEFTETSAVFEDGTMFEAIDSVIFATGYDYSYPFLDETIMKSRNNEVTLFKGIFPPLMEKPTLAVIGLVQSLGAAIPTADLQAWWAAKVFANSCTLPTTNEMMDDTDEKMGKKLKCMFSSFFMFGQS--QTLQTDYITYVDELGSFIGAKPNIPWLFLTDPRLALEVYFGPCSPYQFRLMGPGKWDGARNAILTQWNRTVKPTRTRVVSEVQRPH--PFYNLLKMLSFPLLLLAVTLTFY-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97501-1", "uniprot_id": "FMO3_MOUSE", "id": "P97501-1", "name": "Flavin-containing monooxygenase 3", "aln": "----MKKKVAIIGAGVSGLAAIRSCLEEG--LEPTCFERSDDVGGLWKFSDHIEEGRASIYQSVFTNSSKEMMCFPDFPYPDDFPNFMHHSKLQEYITSFAKEKNLLK---YIQFETPVTSINKCPNFSTTGKWEVTTEK-HGKKETAVFDATMICSGHHIFPHVPKDSFPGLNRFKG--KCFHSRDYKEPGIWKGKRVLVIGLGNSGCDIAAELSHVAQKVTISSRSGSWVMSRVWDDGYPWDMVVLTRFQTFLKNNLPTAISDWWYTRQMNARFKHENYGLVPLNRTLRKEPVFNDELPARILCGMVTIKPNVKEFTETSAVFEDGTMFEAIDCVIFATGYGYAYPFLDDSIIKSRNNEVTLYKGVFPPQLEKPTMAVIGLVQSLGATIPITDLQARWAAQVIKGTCTLPSVNDMMDDIDEKMGEKFK-------WYGNS--TTIQTDYIVYMDELASFIGAKPNLLWLFLKDPRLAVEVFFGPCSPYQFRLVGPGKWSGARNAILTQWDRSLKPMKTRVVSKVQKSCSHFYSRLLRLLAVPVLLIALFLVLI-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9EQ76-1", "uniprot_id": "FMO3_RAT", "id": "Q9EQ76-1", "name": "Flavin-containing monooxygenase 3", "aln": "----MKRKVAVIGAGVSGLAAIRSCLEEG--LEPTCFERSDDVGGLWKFSDHTEEGRASIYQSVFTNSSKEMMCFPDFPYPDDFPNFMHNSKLQEYITSFATEKNLLK---YIQFETLVTRINKCPDFSTTGKWEVTTEK-NSKKETAVFDAVMICSGHHVYPHLPKDSFPGLNRFKG--KCFHSRDYKEPGTWKGKRVLVIGLGNSGCDIAAELSHVAQQVIISSRSGSWVMSRVWNDGYPWDMVVITRFQTFLKNNLPTAISDWWYMKQMNARFKHENYGLMPLNGTLRKEPVFNDELPARILCGTVSIKPNVKEFTETSAVFEDGTVFEGIDCVIFATGYGYAYPFLDDSIIKSRNNEVTLYKGIFPPQLEKPTMAVIGLVQSLGAAIPTTDLQARWAAQVIRGTCILPSVNDMMDDIDEKMGKKLK-------WFGNS--TTIQTDYIVYMDELASFIGAKPNILWLFLKDPRLAIEVFFGPCSPYQFRLVGPGKWSGARNAILTQWDRSLKPMKTRVVGGIQKPC--LYSHFLRLLAVPVL-IALFLVLI-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31513-1", "uniprot_id": "FMO3_HUMAN", "id": "P31513-1", "name": "Flavin-containing monooxygenase 3", "aln": "----MGKKVAIIGAGVSGLASIRSCLEEG--LEPTCFEKSNDIGGLWKFSDHAEEGRASIYKSVFSNSSKEMMCFPDFPFPDDFPNFMHNSKIQEYIIAFAKEKNLLK---YIQFKTFVSSVNKHPDFATTGQWDVTTER-DGKKESAVFDAVMVCSGHHVYPNLPKESFPGLNHFKG--KCFHSRDYKEPGVFNGKRVLVVGLGNSGCDIATELSRTAEQVMISSRSGSWVMSRVWDNGYPWDMLLVTRFGTFLKNNLPTAISDWLYVKQMNARFKHENYGLMPLNGVLRKEPVFNDELPASILCGIVSVKPNVKEFTETSAIFEDGTIFEGIDCVIFATGYSFAYPFLDESIIKSRNNEIILFKGVFPPLLEKSTIAVIGFVQSLGAAIPTVDLQSRWAAQVIKGTCTLPSMEDMMNDINEKMEKKRK-------WFGKS--ETIQTDYIVYMDELSSFIGAKPNIPWLFLTDPKLAMEVYFGPCSPYQFRLVGPGQWPGARNAILTQWDRSLKPMQTRVVGRLQKPC--FFFHWLKLFAIPILLIAVFLVLT-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VHG0-1", "uniprot_id": "FMO4_MOUSE", "id": "Q8VHG0-1", "name": "Dimethylaniline monooxygenase [N-oxide-forming] 4", "aln": "----MAKKVAVIGAGVSGLSSIKCCLDEN--LEPTCFERTSDFGGLWKFADTSEDGMTRVYRSLVTNVCKEMSCYSDFPFREDYPNFMSHEKFWDYLREFAEHFGLLR---YIRFKTTVLSVTKRPDFSETGQWDVVTET-EGKRDRAVFDAVMVCTGQFLSPHLPLESFPGIHKFKG--QILHSQEYRIPDAFRGKRILVVGLGNTGGDIAVELSEIAAQVFLSTRTGTWVLSRSSPGGYPFNMIQTR-WLNFLVRVLPSRFINWTHERKMNKILNHENYGLSIAKGKKPK-FIVNDELPTCILCGKVTMKTSVKDFTESSVIFEDGTTEANIDVVIFTTGYEFSFPFFEEPLKSLCTKKIILYKRVFPPNLERATLAIIGLISLNGSILVGTEFQARWATRVFKGLCSIPPSQKLMAEATKTEQLIKRG------VIKDT--SQDKLDFITYMDELTQCIGAKPSIPLLFIKDPRLAWEVFFGPCTPYQYRLVGPGRWDGARNAILTQWDRTLKPLKTRIVPKSPEPT--SLSHYLIAWGAPVLLVSLLLIYKSSHFLELVQGKLPRRFPPYRLLWYMPQNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K4B7-1", "uniprot_id": "FMO4_RAT", "id": "Q8K4B7-1", "name": "Dimethylaniline monooxygenase [N-oxide-forming] 4", "aln": "----MAKKVAVIGAGVSGLSSIKCCLDEN--LEPTCFERSSDFGGLWKFAEASEDGMTRVYRSLVTNVCKEMSCYSDFPFHEDYPNFMSHEKFWDYLREFAEHFGLLK---YIRFKTTVRSVTKRPDFSETGQWEVVTET-EGKQDRAVFDAVMVCTGQFLSPRLPLESFPGIHKFKG--QILHSQEYRIPDAFRGKRILVVGLGNTGGDVAVELSGIAAQVFLSTRTGAWVRSRSSVGGYPLNMMQTR-WRNFLAQVLPSRFVSWNQERQMNKIFNHENYGLSIAKGKKPK-FIVNDELPTCILCGKITMKTSVKDFTESSIVFEDGTIEANIDVVIFTTGYEFSFPFFEEPLKSLCTKKVILYKRVFPPNLERSTLAIIGLISLTGSILVGTEFQARWATRVFKGLCNIPPSQKLMAEAIKKEELIKRG------VIKDT--SQDKLDFISYMDELTQCIGAKPNIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGRWDGARNAILTQWDRTVKPLKTRTVPKSQEPA--SLSRYLKTWGAPVLIVSLLLIYKSSLFLELVQSKLQGRFSPSRILWYIPQNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31512-1", "uniprot_id": "FMO4_HUMAN", "id": "P31512-1", "name": "Dimethylaniline monooxygenase [N-oxide-forming] 4", "aln": "----MAKKVAVIGAGVSGLSSIKCCVDED--LEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVTNVCKEMSCYSDFPFHEDYPNFMNHEKFWDYLQEFAEHFDLLK---YIQFKTTVCSITKRPDFSETGQWDVVTET-EGKQNRAVFDAVMVCTGHFLNPHLPLEAFPGIHKFKG--QILHSQEYKIPEGFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCCSFIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAK-FIVNDELPNCILCGAITMKTSVIEFTETSAVFEDGTVEENIDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKQVFPLNLERATLAIIGLIGLKGSILSGTELQARWVTRVFKGLCKIPPSQKLMMEATEKEQLIKRG------VFKDT--SKDKFDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKWDGARNAILTQWDRTLKPLKTRIVPDSSKPA--SMSHYLKAWGAPVLLASLLLICKSSLFLKLVRDKLQDRMSPYLVSLWRG---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38866-1", "uniprot_id": "FMO1_YEAST", "id": "P38866-1", "name": "Thiol-specific monooxygenase", "aln": "MTVNDKKRLAIIGGGPGGLAAARVFSQSLPNFEIEIFVKDYDIGGVWHYP-EQKSDGRVMYDHLETNISKKLMQFSGFPFEENVPLYPSRRNIWEYLKAYYKTFIANKDAISIHFSTEVTYLKKK-----NSQWEITSKD-ELRTTKSDFDFVIVASGHYSVPKLPTN-IAGLDLWFDNKGAFHSKDFKNCEFAREKVVIVVGNGSSGQDIANQLTTVAKKVYNSIKEP------------------------------------------------------------------ASNQLKAKLIETVQTIDS--ADWKNRSVTLSDGRVLQNIDYIIFATGYYYSFPFIEPSVRLEVLGEGVTGDKHSSVNLHNLWEHMIYVKDPTLSFILTPQLVIPFPLSELQAAIMVEVFCKSLPITTTFDSNACG---------THNFPKGKDLEYYAELQELLNSIPRRVGHFEPVVWDDRLIDLRNSSYTD------------KEERNVLLAEHAQALKKKKAPYFLPAPHT-------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: ::*.* .** : :. :: * *.**:*:: . :* : * .::: :..:* :. * : . : :* : * *.* * : : .:* : ** ::. * * . : *: : . :*: ::: * : ::* *.:. *:* : . :. * .::: :: : . :.: :* ::: *** :.*: . : * . . : : : : . ::.: . .. * * . * .:::: : : :: ", "identical_positions": 40, "similar_positions": 108, "identity": "6.85%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2646", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4FZU3-1", "uniprot_id": "NSRP1_RAT", "id": "Q4FZU3-1", "name": "Nuclear speckle splicing regulatory protein 1", "aln": "MAIPGRQYGLILP-KKTQPLNRVLQKPSVFGNDSDDD-EASVSESLQREAAKKQAM-------RQTKLEIQKALAEDSTVYEYDSIYDEMQKKKEENNPKLLMGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEAFVTSAYKKKLEERAEEEEREKRAAALEARLDVTKQKDLSGFYRHLLNQAVGEEAVPKSSFREARTVIKEEKLRGYPDETNSENRP-QQNCALQSGVEEAEENPDADSDSE-ESCDDGERGDHKVKSRGEEDTGASTKYLKHHKNHTHSRSSSEEGGLSTKYHSRSS-QSRGHEHKGGQHQDRQSRDQESCHKDRSHREEKSSHRHR-EASHKDHHWKRHEHEDKPKGRGQGERQDREWKREK----YSSREQEKDRQWNDHDRYSEK---EKKGKEKEEHRKARRERCEDGAKYRERKKPEGSGQS------SERHRDRRESSPRPRPEDDLLDQERSSKARNTEKDK-GEQGKPPRSETSLATKHRLTEERPEKGSQPERPPEAVSKFAKRSNEETVMSARDRYLARQMARINAKTYIEKEDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5NCR9-1", "uniprot_id": "NSRP1_MOUSE", "id": "Q5NCR9-1", "name": "Nuclear speckle splicing regulatory protein 1", "aln": "MAIPGRQYGLILP-KKTQPLHRVLQKPSVFGSDSDDD-ETSVSESLQREAAKKQAM-------KQTKLEIQKALAEDSTVYEYDSVYDEMQKKKEENNPKLLPGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMENGEFDDKEAFVTSAYKKKLEERAEEEEREKRAAALEAHLDVTKQKDLSGFYRHLLNQAVGEEAAPKSSFREARTVIKEEKLRGYPDETNSESRPPQQSCVLQRGAQEAEENPDADREFDDESSEDGEKRDHKVKSRGE-DTGASMKHPKHHKNRAHSRSSSEERGLGTKHHSRGS-QSRGHEH-----QDRQSRDQESCHKDRSHREEKSSHRHR-EASHKDHYWKKHEQEDKLKGREQEERQDREGKREK----YSSREQERDRQRNDHDRYSEK---EKKRKEKEEHTKARRERCEDSGKHREREKPEGHGQS------SERHRDRRESSPRSRPKDD-LDQERSSKARNTEKDK-GEQGKPSHSETSLATKHRLAEERPEKGSEQERPPEAVSKFAKRSNEETVMSARDRYLARQMARINAKTYIEKEDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0G5-1", "uniprot_id": "NSRP1_HUMAN", "id": "Q9H0G5-1", "name": "Nuclear speckle splicing regulatory protein 1", "aln": "MAIPGRQYGLILP-KKTQQLHPVLQKPSVFGNDSDDDDETSVSESLQREAAKKQAM-------KQTKLEIQKALAEDATVYEYDSIYDEMQKKKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEAFVTSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSFREARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEE-NPDADSDFDAKSSADDEIEETRVNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQSRDQENHYTDRDYRKERDSHRHR-EASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDREKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGVQS------SERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTEEGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARVNAKTYIEKEDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q568R1-1", "uniprot_id": "NSRP1_DANRE", "id": "Q568R1-1", "name": "Nuclear speckle splicing regulatory protein 1", "aln": "MATSGKQYGLILP-QKRASKSAPLARPSVFGDDSDDE--TSVGESLQKEAIKKKMM-------KQTRLEMQKALEEDSTVYEYDNVYDDIQKQRLESNKKLLGGEDKKPKYINQLLRAVEERKKEQERRDERKIQKEREAEGEKFADKEAFVTSAYRQKLKERQEELEREKREAELEAALDVKKQKDLSGFYRHFLNQTVGEEVVPD------RSAQSEEK----ATSSAAAERSPSPESTANRRESEAESHSDDD----------------QVDVKPAFSKTTANNHAKRQYRQKSPLSDSDDG--DERERERKEIKEKSHKD-----RDRD-RAKE---KERERMRDKDKHSHRKEDRGGDRRRERDREEDRARDRRDRDRNDRHGIRDR--RNSSPKDRERDRKGERDRR-------DNSPKDRERDRKGERDRRDNSPKDRERETRDKSPKDRRDKSPKDRDRERRDKSPKDREPERKGERDIREREDNKVDSQRKNQEDEKSSKS--KTEHGKEEKLVEETENSSGAQQEISKFAKRSSDQTVSSARERYLARQLARFASKSYVEKEED", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYE3-1", "uniprot_id": "Q9VYE3_DROME", "id": "Q9VYE3-1", "name": "Nuclear speckle splicing regulatory protein 1 N-terminal domain-containing protein", "aln": "---MAKQYGLILPGQQKKVPLKRVERPSIFDENSDSETDDDPAAPQFQPRTGGVSMGPSLMERRVARRQQEKALAEDPTIFQYDELYDDMDSKREE-AKQTKSQEPRKPKYIGRLMEHAERRKLEKELRIERQVQKDREAEGEMYKDKDTYVTAAYRKKLESIRQMQEQEQRDEYLEAIGDVTKQKDLDGFYRHLYEQKLG--------------------------------------GPAQQDVVKPKTAPTTD----------------EVAYKPIKAEAVKHRSYRRRRPS--------------------------------------------------------------EDEEEQTKSKSDAASDATKSTDQTESIPAQAHLTN-------------------------------NIDADSDFSIDDSSDEEDEKENEKEKNKLSQIK----------KEDKDKAPESSEPVKPKEPEASQQSPTKKDDS----------------NAEVNEKDLPVPRVTKPPVDRTLFWRKRTVGEVLAAALARYEERKRARLQ----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:******* :: : :**:*..:**.: . . . : * : :: : :*** **.*:::**.:**:::.:: * : : :***** .*:. .* ** *:* * *:::*::** * : **:::**:**::**:. : *:*:* *** **.*****.*****: :* :* : : . * .* : . . ::: * : : . .* : : : . : . . . ::. * .:::. . . :: ::.:*. : : .: . ... : *: . . : : **. :.: :* ** *: **. ", "identical_positions": 84, "similar_positions": 123, "identity": "14.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2649", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NCE2-1", "uniprot_id": "MTMRE_HUMAN", "id": "Q8NCE2-1", "name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14", "aln": "-MAGARAAAAAASAGSSASSGNQPPQELGLGELLEEFSRTQYRAKDGSGTGGSKVERIEKRCLELFGRDYCFSVIPNTNGDICGHYPRHIVFLEYESSEKEKDTFESTVQVSKLQDLIHRSKMARCRGRFVCPVILFKGKHICRSATLAGWGELYGRSGYNYFFSGGADDAWADVEDVTEEDCALRSGDTHLFDKVRGYDIKLLRYLSVKYICDLMVENKKVKFGMNVTSSEKVDKAQRYADFTLLSIPYPGCEFFKEYKDRDYMAEGLIFNWKQDYVDAPLSIPDFLTHSLNIDWSQYQCWDLVQQTQNYLKLLLSLVNSDDDSGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVDRLSKGEEIFFFCFNFLKHITSEEFSALKTQRRKSLPARDGGFTLEDICMLRRKDRGSTTSLGSDFSLVMESSPGATGSFTYEAVELVPAGAPTQAAWRKSHSSSPQSVLWNRPQPSEDRLP----SQQGLAEARSSSSSSSNHSD-NFFRMGSSPLEVPKPR-SVDHPLPGSSLSTDYGSWQMVTGCGSIQERAVLHTDSSLPFSFPDELPNSCLLAALSDRETRLQEVRSAFLAAYSSTVGLRAVAPSPSGAIGGLLEQFARGVGLRSISSNAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VEL2-1", "uniprot_id": "MTMRE_MOUSE", "id": "Q8VEL2-1", "name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14", "aln": "-MAGAR-AAAAASAGSTASSGSPPPQEPGLWELLEEFSRTQYRAKDSGGKSGSKVERIEKRCLELFGRDYCFSVIPNVNGDICGHYPRHIVFLEYESSEKEKDTFQSTVQVNKLQDLIHRSKMARCRGRFVCPVILFKGKHICRSATLAGWGELYGRSGYNYLFSGGADDTWASTEDVTEEDFVLRSGDTHLFDKVRGYDIKLLQYLSVKYICDLMVENKKVKFGMNVTSSEKVDKAQRYANFTLLSIPYPGCEFFKEYKDRDYMAEGLIFNWKQDYVDAPLNIPNFLTQSLNIDWSQYQSWDLVQQTQNYLKLLLFIMNRDDDSGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKPAEILYLTVAYDWFLFGHMLVDRLSKGEEIFFFCFNFLKHITSEEF-CLKTQRRKSLPTRDAGFTVEDICMLRHKDRGSTTSLGSDFSLVLEHSPGAVGSFSYETVELAPAGAPTQAAWRKSHSSSPQSMLWSRPQPSEERLP----SHHGLTEAKSSSSSSSNHSD-NFFRMGSSPLEVPKPR-SVDHPLPGSSLSTDFGSWQLVSGCGSIQDRPVLHTDSSLPFSFQDELPNSCLLTALSDRETRLQEVRSAFLAAYSSTVGLRAATPSPSGAIGGLLEQFARGVGLRGTSTSTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F0C5-1", "uniprot_id": "E7F0C5_DANRE", "id": "E7F0C5-1", "name": "", "aln": "MMMASR------------------SEE--LTDLIDVFSKSQYRAKEVTPG----VERIEKRYLELFDRDYKYSIIHNTNGEVCGHYPRKIVFLEYECSDNNKESFESTVQISKLQDLVNRSKMARCRGRFVCPVILYNGKHVCRSSTLAGWGELYGRTGYNYIFSGGTDDSLGEAEEVLEDDCAVRNGDSQLFDKVRGSDIKLLKYLSVRYICDLMVENKKVKFGLNVTSSEKVDKAQRYADFTLLSVPYPGCEFFREYKDRDYTAEGLVFNWNQDFVDAPLTIPVCFTRNLNINWSEYQSWDLVQQTQNYLKLLLHIINSDDENGLLVHCISGWDRTPLFVSLLRLSLWADGAIHASLEPSEILYLTIAYDWFLFGHMLPDRLSKGEEIFFFCFNFLKHIVCESFSVVKKQRRKNSHFKDADFTVDDLCQLKSRDRGSVTSLSSDFSLITEDAS-ASPSLQAEATDLITLG-PQASNGRKGMPLAAHSVLWNRPITSEERIPNVINEPSPLGSFKSSSSSSSNHSDQNATRTGSTPLAVPGRRPVVEYARSGSSVSTDYGSWQIVSGCGSIHDLPPVPSESPLPFSFQDEGPSGRMCTFVPERQVRLEAVREMFLSAYSSTVGLKSSSPSPSGALSGLLEQFARGVGLRGTNAII-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .:* .:* * :*:: **::*****: ******* ****.*** :*:* *.**::******:*******.*:::*::*:****:.*****::*****************::***:***:***********:****:****:**: ...*:* *:* .:*.**::******* *****:****:***************:***************:*****:********:******* ****:***:**:*****.** :*:.***:**:**.*************** ::* **:.****************:*********** **:**:*:******:*********** ********************..*.* :*.****. :*..**::*:* *: :****.***.*****: * :. * *: *:.:* . * * : **. . :.:*:**.** .**:*:* . * . :*********** * * **:** ** * *::. .***:***:****:*:*****:: . : ::*.***** ** *.. : : :.:*:.**: **. **:********:: :******:.*************. .: ", "identical_positions": 408, "similar_positions": 145, "identity": "62.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2656", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIH7-1", "uniprot_id": "WNK1_RAT", "id": "Q9JIH7-1", "name": "Serine/threonine-protein kinase WNK1", "aln": "----------------------------------------------------------------------------------------------------------MSDGTAEKQSGTPG--FLSPPAPVPKN--------------------------------GSSSDSSVGEKLGAAVADSGIGRTEEYRRRRHTMD------------------------KDSRGAAATTTPTEHRFFRRSVICDSNATALELPGLPLSIPQPS------------------------------------------------------------VPAVVPQSAPPEPHREETLTATVASQVSQQPSAAASPGEQAVVGSATATVPSSTS--KDRPVSQPSLVGSKEEPP------PSRSGSGSGGASAKE------------------PQEERNQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEED----DGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKRKQEESSFKQQNEQQASVSQAGIQPLSVASTGIPTAPTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYG----SQHEQAHSIGTAPG-------HTVSSIQAQ----SQPHG-------------------------------------------------------------------------------------------------VYPPSSMAQG----------------------------------------------QNQGQPSSS-LAGVLSSQ----PVQHPQQQ-GIQPTVPPQ-QAVQYSLPQAASS-SEG-TVQPVSQP-------------------------------------QVSAGTQS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STQGVSQAAPPEQTPITQSQPTQPVP------LVSSVDSAHSDVASGMSDGNENAPSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIATIMVNNDFILAIERESFVAQVREIIEKADEMLSEDVSVEPEGDQGLESLQGKDDYGFPGSQKLEGEFKQPIAVSSMPQQIGVPTSSLTQVVHSAGRRFIVSPVPESRLRESKIFTSEIPDPVAASTSQG----PGMNLSHSASSLSLQQAFSELKHGQMTEGPNTAPPNFNHPG---PTFSPFLTSIAGVQTVAASTPSVSVPITSSPLNDISTSVMQSEGALPTDKGIGGVTTS-TGVVASGGLTTLSVSETPTLSSAVSSSTAPAVVTVSTTSQ--PVQASTSGSIASSTGSFPSGTFSTTTGTTVSSVAVPNAKPPTVLLQQVAGNTAGVAIVTSVSTTTPFPAMASQPSLPLGSSTSAPTLAETVVVSAHSLDKASHSSTAGLGLSFCAPSSSSSSGTAVSSSVSQPGIVHPLVISSAIASTPVLPQPAVPTSTPLLPQVPNIPPLVQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPEMDADTQSKAPGIDDIKTLEEKLRSLFSEHSSSGTQHASVSLETPLVVET-VTPGIPTTAVAPSKLMTSTTSTCLPPTNLPLG-TAGMPVMPVGTPGQVSTPGTHASAPASTATGAKPGTTPPKPSLTKTVVPPVGTELSAGTVPCEQLPPFPGPSLIQTQQPLEDLDAQLRRTLSPETIPVTPAVGPLSTMSSTAVTEAGSQPQK---DGTEVHVTASSSGAGVVKMGRFQVSVTMDDAQKERKNRSEDTKSVHFESSTSESSVLSSSSPESTLVKPEPNGITVSGISLDVPDSTHRTPTPEAKSETGQPTKVGRFQVTTTAN-KVGRFSVSRTEDKVTELKKEGPVTSP-FRDSEQTVIPAAIPKKEKPELAEPSHLNGPSSDLEAAFLSRGGEDGSGSPHSPPHLCSKSLPIQTLSQSLSNSFNSSYMSSDNESDIEDEDLRLELRRLREKHLKEIQDLQSRQKHEIESLYTKLGKVPPAVIIPPAAPLSGRRRRPTKSKGSKSSRSSSLGNKSPQLSGN--LSGQSGTSVLNPQQTLHPPGNTPETGHNQLLQPLKPSPSSDNLYSAFTSDGAISVPSLSAPGQG---------------------------------------------TSSTNTVGGTVSSQAAQAQPPAMTSSRKGTFTDDLHKLVDNWARDAMNLS-GRRGSKGHMNYEGPG----------MARKFSAPGQLCISMTSNMGGSTPISAASATSLGHFTKSMCPPQQYGFPAAPFGTQWSGTGG-------PAPQPLGQFQPVGTTSLQNFNISNLQKSISNPPGSNLRTT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P83741-1", "uniprot_id": "WNK1_MOUSE", "id": "P83741-1", "name": "Serine/threonine-protein kinase WNK1", "aln": "----------------------------------------------------------------------------------------------------------MSDGAAEKQSGTPG--FLTPPAPVPKN--------------------------------GSSSDSSVGEKLGATVADSGVGRTEEYRRRRHTMD------------------------KDSRGAAATTTPTEHRFFRRSVICDSNATALELPGLPLSIPQPS------------------------------------------------------------VPAVVPQSAPPEPHREETLTATVASQVSQQPSAAASPGEQAVVGSATTTVPSSTS--KDRPVSQPSLVGSKEEPP------PSRSGSGSGGASAKE------------------AQEDRSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEED----DGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKRKQEESSFKQQNEQQASVSQAGIQQLSAASTGIPTAPATSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTIDSGQGSSVFTESRVSSQQTVSYG----SQHEQAHSTGTAPG-------HTVSSIQAQ----SQPHG-------------------------------------------------------------------------------------------------VYPPSSMAQG----------------------------------------------QNQGQPSSS-LAGVLSSQ----PIQHPQQQ-GIQPTVPSQ-QAVQYSLPQAASS-SEGTTAQPVSQP-------------------------------------QVSAGTQLPVSQTVATVQGEPHIPVSTQPSVVPVHSGAHFLPMGQPIPTSLLPQYPVSQIPISTPHVSTAQTGFSSVP-----------------------------ITMAAGINQPLLTLASSATASSIPGGSPVVPNQLP------TLLQPVNQLQSQVHPQLLQPTTVQSIGIPANLGQAAEGPLPSGDVLYQGFPSRLPPQYPGDS--------------NIAPSSNVASVCIHSTVLAPPSMPTEALATQGYFPTVVQPYVESTPLVPMGSVGGQVQVSQPAVSLTQQPPTTSSQQAVLESTQGVSQAAPPEQTPITQSQPTQPVP------LVTSADSAHSDVASGMSDGNENAPSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIATIMVNNDFILAIERESFVAQVREIIEKADEMLSEDVSVEPEGDQGLESLQGKDDYGFPGSQKLEGEFKQPIAVSSMPQQIGVPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFTSDISDPVVASTSQA----PGMNLSHSASSLSLQQAFSELKHGQMTEGPNTAPPNFNHMAG--PTFSPFLASIAGVQTVAASTPSVSVPITSSPLNDISTSVMQSETALPTEKGIVGVTTTSTGVVASGGLTTMSVSESPTSSSAVSSSTVPAVVTVSTPSQ--PVQASTSGSIASSTGSFPPGTFSTTTATTMGSVVAPDAKPPTVLLQQVASNTAGVAIVTSVSTTTPFPGMASQPSLPLSSSTSAPTLAETMVVSAHSLDKASHSSTAGLGLSFCAPSSSSSSGTAVSTSVSQPGMVHPLVISSAVVSTPGLPQPVVPTSTPLLPQVPNIPPLVQPVVNVPAVQQTLIHSQPQPALLPNQPHTHCPEMDADTQSKAPGIDDIKTLEEKLRSLFSEHSSSGTQHASVSLETPLVVETTVTPGITTTAVAPSKLMTSTTSTCLPPTSLPLG-AAGMPVMPVGTPGQVSTPGTHASAPVGTATGVKPGTTPPKP--TKTVVPPVGTELSAGTVPCEQLPPFPGPSLIQSQQPLEDLDAQLRRTLSPETITVAPAVGPLSTMSSTTVTEAGTRLQK---DGTEGHVTATSSGAGVVKMGRFQVSVTMDDAQKERKNRSEDTKSVHFESSTSESSVLSSSSPESTLVKPEPNGISISGISLDVPDSTHKAPTPEAKSDAGQPTKVGRFQVTTTAN-KVGRFSVSRTEDKVTELKKEGPVTSPPFRDSEQTVIPAVIPKKEKPELAEPSHLNGPSSDLEAAFLSRGTEDGSGSPHSPPHLCSKSLPVQNLSQSLSNSFNSSYMSSDNESDIEDEDLRLELRRLREKHLKEIQDLQSRQKHEIESLYTKLGKVPPAVIIPPAAPLSGRRRRPTKSKGSKSSRSSSLGNKSPQLSGN--LSGQSGTSVLHPQQTLHPAGNTPETGHNQLLQPLKPSPSSDNLYSAFTSDGAISVPSLSAPGQG---------------------------------------------TSSTNTVGGTVSSQAAQAQPPAMTSSRKGTFTDDLHKLVDNWARDAMNLS-GRRGSKGHMNYEGPG----------MARKFSAPGQLCVPMTSNLGGSTPISAASATSLGHFTKSMCPPQQYGFPPAPFGTQWSGTGG-------PAPQPLGQFQPVGTASLQNFNISNLQKSISNPPGSNLRTT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4A3-1", "uniprot_id": "WNK1_HUMAN", "id": "Q9H4A3-1", "name": "Serine/threonine-protein kinase WNK1", "aln": "----------------------------------------------------------------------------------------------------------MSGGAAEKQSSTPGSLFLSPPAPAPKN--------------------------------GSSSDSSVGEKLGAAAADAVTGRTEEYRRRRHTMD------------------------KDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPS------------------------------------------------------------IPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTS--KDRPVSQPSLVGSKEEPP------PARSGS--GGGSAKE------------------PQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEED----DGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKKQEESSLKQQVEQ-SSASQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYG----SQHEQAHSTGTVPG-------HIPSTVQAQ----SQPHG-------------------------------------------------------------------------------------------------VYPPSSVAQG----------------------------------------------QSQGQPSSSSLTGVSSSQ----PIQHPQQQQGIQQTAPPQ-QTVQYSLSQTSTS-SEATTAQPVSQPQ------------------------------APQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQPLPTPLLPQYPVSQIPISTPHVSTAQTGFSSLP-----------------------------ITMAAGITQPLLTLASSATTAAIPGVSTVVPSQLP------TLLQPVTQLPSQVHPQLLQP-AVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDS--------------NIAPSSNVASVCIHSTVLSPP-MPTEVLATPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAP-TTSSQQAVLESTQGVSQVAPAEPVAVAQTQATQPTT------LASSVDSAHSDVASGMSDGNENVPSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQGLESLQGKDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQS----PGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPNFSHTGPTFPVVPPFLSSIAGVPTTAAAT--APVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATS-TGVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLCIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLG-TVALPVTPVVTPGQVSTP------VSTTTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGRFQVTTTAN-KVGRFSVSKTEDKITDTKKEGPVASPPFMDLEQAVLPAVIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVDDGSGSPHSPHQLSSKSLPSQNLSQSLSNSFNSSYMSSDNESDIEDEDLKLELRRLRDKHLKEIQDLQSRQKHEIESLYTKLGKVPPAVIIPPAAPLSGRRRRPTKSKGSKSSRSSSLGNKSPQLSGN--LSGQSAASVLHPQQTLHPPGNIPESGQNQLLQPLKPSPSSDNLYSAFTSDGAISVPSLSAPGQG---------------------------------------------TSSTNTVGATVNSQAAQAQPPAMTSSRKGTFTDDLHKLVDNWARDAMNLS-GRRGSKGHMNYEGPG----------MARKFSAPGQLCISMTSNLGGSAPISAASATSLGHFTKSMCPPQQYGFPATPFGAQWSGTGG-------PAPQPLGQFQPVGTASLQNFNISNLQKSISNPPGSNLRTT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PXY8-1", "uniprot_id": "A0A8M9PXY8_DANRE", "id": "A0A8M9PXY8-1", "name": "non-specific serine/threonine protein kinase", "aln": "----------------------------------------------------------------------------------------------------------MSS---ENPNKVVT--FLAPPPPKNVN--------------------------------GSGSDSLVGEKL-----------DTEVRKRRHTMD------------------------KDLK-------TAEHRFFRRSVICDSNATALDLPSKACILTSPPDCEQFV------------------------------------------------------IPTVLSSTPDVTLDTQTVVSAAVVEERSEDERRAGVEGIVEVQSPSVQDAGSRQSEVLGKVETELSDVGDKEQESRVTDKQEEEERGVAKARAEAE------------------LREAVKKEQDEIEEVETKAVGTSPDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLSRSERQRFKEEAGMLKGLQHPNIVRFYDSWESPSKGRKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLHFLHTRAPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRSSFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNPAQIYRRVTSGVKPGSFDKVAIPEVKEIIEGCIRQNKDERYAIKDLLNHAFFQEETGVRVELAEED----DGEMIAIKLWLRIEDVKKLKGKYKDNEAIEFSFDLHRDVPDDVAQEMVESGYVCEGDHKTMAKAIRDRVSLISRKREQRQQVRAEQEKRKQEE-----EQKLLSSESIKNVAGAQGTQGSLQSQCSSQPPTPGLVQPECEEPDADPQHQYMQSGIT-LADGTFDSGQGSSVFSEPHLS-QLSMSYSSPGTSQQQQVPGQGTYTPSSQAPQQHTAYPQQPMPQSVSQPYGGGGSGLVEPPLFFPTIPERPVSFSPPPSCPPKAFNVQRRKSTSILEAHTRHFQPAYHRSYGSSLHPFSGVEALGATVEPSMFMMPGMPAQRLADPLHLQPPTESLYGYKDVRAEQEETVRRLSLNQAALMDHLEAMAYSGYPMTAHQLSHISFHQQMQAAAASLAYETQSQQPGPAYLHPHLQSHMRLTHSPIPQLPPMSVPSSASAPQQATVADPSYQSHSFPHSAPPVLAHASEPNTAFEFHMHNLQADPAMLASRLYRARRGSMDLNLEEAGGNPGLCSRLQPVTEELYSYVSPELPLPPGSLLLHGPKELSPEPSSDSMTSSDAGEFHSPPPHQLYQTQECSAAQSIPQAAYYKTDGGSNVSDGHPPSQPTFLFVPHSESSTISSSHINAWARQPSLPPDLTFHEPALSHQGATLVQVPIPQSTSGMSLASCSTPAASASQQYGVYYVQALPTQAPVQQPASLGPTSQPCASLPQQQTPQQPSSTVAQSISQTQITPTQLCSPALCVPTIAVTPFQQQPVPEALTSLKTAPATSPSMLPPHVPLLVTTPVPTIHVATVPSPTEHPCLPADALAQTSHSASQTLTTELSQLQTPAVESSHSDVASGLSDGNEGVTG--GRHEGRPAKRHQRRSVRSRSRNEKTSKVKLSVLNISSMGDRVAECQLETHNRKMVTFKFDLDGDNPEEIAQIMVQSEFILESERESFIDRIREVIETADEKG-----VERERSQ-----------MASDHEQLMPTTSAPLEHG-RTYNLSVPPSSAAQVVHSAGRRFIVSPVPESRLKDQFFSPSQPTIPLHEEPAPVPVALPALGLSVSASAVSLQQAFTEMRQAHFDPGPSTAPPMLHNSMP------PLLPATT------------PLPSSATP-----------------------------------------VVSPPVSSEVTSSPSLPSIN--------------------------PPVSSSPPPTVPVNSVTSP----PAQLTLPQSQVAPAVISVIPTPSTLPMPAVPTATSLPQTSVTVP-------------------SSTP------IAPMGSVSGGSGE-----QPSIPATSSPTSATIQTPQLAPSTIPTTT----AQSQVPPLQPVTTTMPVVQPTPVHSQPQTTTVPNQSHAHSVECDSDQQGK---VDDIQALDKKLRSLFMDLGS-----GPPSAQSDVTSDPTATPSVPGTSSP--TTCATPSGTPLPPSSLPLNSSTQSAGSPMTSMGNASTP------------VGYSQTTPSKAPLTRLPVLPVGPDQ-AGTPPTEHLPPFPGPGLIQSQQPLEDLDAQLRRALSPETVPIS----SVTHQSSLTGMPPGGQPVP----FSLDDEQAAAPAAGGYKLGRFQVSVATDENTTQTPTSSSSSTSSSSTTSSS-SSSCSLSSPENTLHRTSSPLIDTG---ADVVDGLPALPN--QTTTQPQPTTIGRFQVTTKTDTQVGRFSVSKAQDEVTTSTSQ-------------------------PQPTPQTHS----------------AVGNGPAQSP--------------GSLNNSISS-YFSSDNDSEFEDEDFKREVSRLRDKHMIESQALYSRQKAEIEALFARLGKVPPAMVNPPVVNPAGRRRRPTKSKSSKSSRGSSQASKSPVQPATSTLSAQSAPSVYPAQQAFLAPGGMMDGGSSPLLQSFKPSPSNDNLCSTFTSDATLSAPSLCVTSQGCVKFSCGSERVTFKPGGRRTRFLSTPCLALWKMVKKVCPCNQLCRTSSTNTVAG--PGQNQSQPPVSQSQSCKGMFTDELHKLVDNWARDAMNLSQGKRGSKHQQQVVPQGHSYEMVPPVNMGRKYSAPGQLCPSIASTLSGHPPMPNTPATSLGARKGSLCPTPQYGYPSAPYSAQWAGAATHTQAGLLATSQPLGQYPQVPTP-LQTFHISTLQKSVSHPGGPNLKST", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PGC5-1", "uniprot_id": "WNK_DROME", "id": "M9PGC5-1", "name": "Serine/threonine-protein kinase Wnk", "aln": "MGQTLCDFVRQQEVVPANRARKGSAISEDGTTSCTTQPQRNTSISSEEQTVQGANIQKSGHRSFNRSASSRQKPNPTSKLKDTLNRKPTCKQGTLSAHTSTSSTTSIQSSPIEPASSLPTLNTTPTPPAASKSNLFVRVLRRFSNNTLPGKTASSPKNVDDVPKVNDNNNGDLGKQQSTDVEVLCSQDNQSREQNEDEMDSKIEPADAISNQKAGLTSGKPKKDKSVKGTSQAVVSDTKKMEARKSSSDTVIEPLIKQQAPLHSSKTTPTTLTANFVQNIRFVRKNVEQSGRNTNPLQFVELETEFPRDYDDNIEMLSREAEHLEEQFRTPTRSNATDATSHHVAGIIDNIITEASRSLTIEKTEDDVPLKSSTKHSSGVKRVGFQVEDKDDTEVQSEKQAKSFDDITKKAESSEASAEEAAVTGSSTDASASPLPSTSLVSTTSSATSITKSKSDEDDDPVAMSPCGRFFKYDKEVGRGSFKTVYRGLDTLTGVPVAWCELLDKQVKKSERTRFREEADMLKKLQHPNIVRFYTYWEFPIGRKKNIVLVTELMLSGTLKSYLKRFKKIHPKVLKSWCRQILKGLNFLHTRQFPIIHRDLKCDNIFITGTTGSVKIGDLGLATLKNRSHAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMAISEYPYSECKGPAQIYKKVISGIKPAALAKVEDPNVRDIIERCIELKKEDRPSCNELLESEFFDEDIGIRVEPTASEQFLSDPSISIIEFRLRFMDPKKRSSRHKENEAIQFEYNIRHDEYEQIAQEMMKENIISEDDSRAVARLLKVQVVSLLKERAQRQTQIKLQNEKSRLEKLALQKQRESLPTNVDEDEEEEEESEDEEDGVKWNQRLQLRYDLLNTDSETSLALSTNSVEPQQLSTRSNTSIPNSGIQQPVQVPGQVPVSQLISVQPQAIPSPAIPMQQK-------PTVHYIQPPQLASYQNSN-------------------------------------------------------------------------------------------ASMQEMTNNQVISPTG----------------------------------------------SQQMQQQQPVVAPTVNHQ------VMPQQQVNQQQQQPQMMQQIPQQVQVQQPQ--TVLPPQPHEQQP-----------------------------------QQQQQPLQQQLQQLMHTNVQAPDLTQQQQMAQQQAQQYFQQQQQQPQQAVNMQQAYAMQQAGQQQQ-------------------------------------------------------------------------------------LSQPLQIQQQILQQQQVAVSHQQQIMQQQLAQHQLQQLQQQQLQQQQLQQQQQIQQQQLQ-------------------------------------------------------------------------------QQQLQQQQFVQQYAQAMPQQQHQQLVTGSQVMAPHQHQQPIQ------IPVQMQVPPTSVAPPIQHTYNQQGGQVTLSDAQQQQHPGFSAVPQQAAPFIQQPTQQPIQLSMPLEQQLQQLLHSQPAQQQQAMSQQQQQPLVQQQQLPLVQQQPPLVQQQQPLVQHQQPSVQHQQPLVQ-----------------------QPQQQQPQPQNQQPQPQTQQTHVVQQQPPQQQPAVEQISQISSQVPVQQENLQPIQVNKDANVATDAMSLNSAHG-----ALEPAPKTEPQNSADAEKQQKQTGTGTRSQKPRRSNRSG--NERIPKLSVTSVDEGSVINCHMENKLKTITFKFDIGDVNPVEIAN--------------------------KLIAQDLLSNCQSTVFVEMINEIVDQVK-----------------QNPNQIPIPTNYRRNIEKVRHASLTRQRSTFRSHQRHRSRDETASDITKMFEPTIHGVETLPSGGGGAEQSNCNLTLEARSHLSNIPNAKEPQLNVSTPPTTTSTMSSSSTASRDAPNSSNDVTIGSGSVSRKTSTASEYTSLSIDYMPDSNITPTGPEPPLDDGKDKKPCSLAIARMQKLLESAGNGAPRSLNLPLNRHLKIQEDLKHTRSLDDLTAVKITFDMPNKAALDTSENAQQATEAEAEKPKDKSGQAVGNQGTGAANTLEQLKIELENITHAHAFASAVVASIN-----------NRAPHQASPAMSSLKATSGQPQTQEITKPNNGAG--PSVPSVGQNTPTAALTSARGSGSSVYNSRRTSIDNSVGSDMHLHTATNLEGTVSNPD---PIPTEASVGITIATGHEKQLSKQPSLEKPSATSILTNNSDPPQRNPSNGSINQNSIADLEKKLAALRNTEN-------TEESATATLSVVPKQVEEVVNPSARKISRFSVSRVQE---QKTSTGVEEPAQGQLKIDLQVAGPGGQVQTNNSVQNGSVVNTPTEVISSPIQNVPLAINGIQLMYQQPQQIHQLPGGTSTTTSGAGTQCIVVPQVVNQNGTHVQQPSNLQPQQQSVHPNMTQQPQQTPLNGHPSMVNTLQQQPPQQSLPMQTIQSQQQQHNQMPIISQQQQQQILMQQQQQQGSQQGSQQFNLPGTQQTHPQHQFIQSQPNQLHSLPPQVVSMAQGNLPHQLPPMQTMGAQQQMISQQQHQLQMQSHMHQQN---------------------------------VPGMYNQQTGARVAAPQNFAGAVPNHLLQQSPLMASQQPAQPMQHVMQPIFNATSGEVTEEPVSLAATHPHLLPSDIQS-------DIKHNLDSLVNQLCNTRLGTNQHQRLLLLRQRQLIEEDELRLKHYVEYEKFQKALRQSISTNVP-----------ANAAYYSAAAAQLPTNLAAPAAPSSSNPTSTSSANT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. * . ..*.. . ....:. :*:: . .:... ** *. : . ::: *. .*: .* . .... ... ..:. . : : :.. . : ..: . : . ..*: . .. : . .. .. .: : ..*. * ***:*:* *:*********:**** * * ****** *:::.:*** **:*** *** ********** ** . :* ******** *****:****** :: ***:**********:***** ****************.***************. *.******************:****************** ********:..****::* **:**.:: ** *:*::*** **. :*::* : ::**: **:*: *:*** : .: * . *:: **: * ** ..::*:****:*.:::.:* :::****::.. :.*.* :::*: :: :* : ::* *** *:::.: * : . . . . . . : :.: . . *: : * .*.: ::. * .:* .* . *. * . * .* * . :: . * *: * : . * .: . :* * : : . . : . *. : . :.**. :.. : . :.: :: :* .:: . : : ::: : . :: ::. : : :: :*:.: * :::.:: : : :: : . :: . * . : ... .*.. .: ** :..*: . . . . *. :..: . :.* :* :: : *. : * : * *. : : : : *. *: : * .. . . . :. * : . :. . .. * .:. . .. .. . . : *. : . : .: : :.. . . : ::: ..* .* : . : . :. : . . . :.: . .* : .. : .* ::*. . . * : . *..*. . . .* . .. . ... .: . . : . : .:* * * *: . . *. . * . .* . .. :* ... .. . .. .:.**.*: : : *.. : . : .: . . .. .: *. .: ...* . ::. : ::. : : . : : : .: . .:::: .:..:.*. ..:. ... * .:* . . . . * : : * : . . ::.: . *. .::.:.... .: . * :.. : . :: :.: : :. : . . .:: : . * .*** . .. : : : :* . . : . . : . :. * . : * *:* ... .*", "identical_positions": 315, "similar_positions": 556, "identity": "10.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-267", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ESU6-1", "uniprot_id": "BRD4_MOUSE", "id": "Q9ESU6-1", "name": "Bromodomain-containing protein 4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTESGPGTRLRNLPVMGDGLETSQMS-TTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKE------TGAAKPGVSTVPNTTQAS---TSPQTQTPQQNPPPPVQATTHPFPAVTPDLIAQPPVMTMVPPQP----------LQTPSPVPPQPPPPPAPVPQPVQSH----PPIIATTPQPVKTKKGVKRKADTTTPTTIDP-IHEPPSLAPEPKTAKLGPRRESSRPVKPPKKDVPDSQQHPGPEK---SSKISEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVTVSSPAVPPP----TKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKKKE--------------EVEENKKSKTKELPPKKTK---KNNSSNSNVSKKEP--VPTKTKPPPTYESEEE---------------DKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPS--LKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESTSESSSSDSEDSETEMAPKSKKKGHTGRDQKKHHHHHHPQMQPAPAPVPQQPPPPPQQPPPPPPPQQQQQQ----PPPPPPPPSMPQQTAPAMKSSPPPFITAQVPVLEP-QLPGSVFDPIGHFTQPILHLPQPE--LPPHLPQPP-----EHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPTR---------------------PPAVSPALAQPPLLPQPP-----------------------MAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQ-KVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQQLQPQPPPPPPPQPQPPPQQQHQPPPRPVHLPSMPFSAHIQQPPPPPG-QQPTHPPPGQQPPPPQPAKPQQVIQH-----HPSPRHHKSDPYSAGHLREAPSPLMIHSPQMPQFQSLTHQSPPQQNVQPKKQVKGRAEPQPPGPVMGQGQGCPPASPAAVPMLSQELRPPSVVQPQPLVVVKEEKIH-SPIIRSEPFSTSLRPEPPKHPEN-IKAPVHLPQRPEMKPVDIGRPVIRPPEQSAPPPGAPDKDKQKQEPKTPVAPKK--DLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEHFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQQQQRQEQQQQQQQ-------AAAVAAASAPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZGX8-1", "uniprot_id": "D3ZGX8_RAT", "id": "D3ZGX8-1", "name": "", "aln": "MTRGRARSVRDDISALAAAAGLFVLLSRSRGTEAVAAAAAAAAAAAAGGARRQAGPVSAAAQQARRTGPGLAQASRTACGGVRPSVSGEDRCPSRPRGGLPGAPRRGPRNLHCVMEPVRHHLRHRRGAGVGRPQFRGPGACCCSRSAGAARAVGAAAAGWARGLSIGAVAAAAVPLGAGCSRERDRGRGRAGRRDGRPGAGGGRAKLPALPAAAILSSEEEEEEEAAAAGSAVRARPVVPGEECDGITSMSTESGPGTRLRNLPVMGDGLETSQMS-TTQAQAQPQSANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKE------TGTAKPGVSTVPNTTQAS---TSPQTQMPQQNPPPPVQATTHPFPAVTPDLIAQPPVMTMVPPQP----------LQTPSPVPPQPPPPPAPVPQPVQSH----PPIIATTPQPVKTKKGVKRKADTTTPTTIDP-IHEPPSLAPEPKTAKLGPRRESSRPVKPPKKDVPDSQQHPGPEK---SSKISEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVTVSSPAVPPP----TKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKKKE--------------EMEENKKSKAKELPPKKTK---KNNSSNSNVSKKEP--APTKTKPPPTYESEEE---------------DKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPS--LKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESTSESSSSDSEDSETEMAPKSKKKGHTGRDQKKHHHHHHPQMQPAPAPVPQQPPPPPQQPPPPPPPQQQQQQQQQQPPPPPPPPSMPQQTAPAMKSSPPPFITAQVPVLEP-QLPGSVFDPIGHFTQPILHLPQPE--LPPHLPQPP-----EHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPAR---------------------PPAVSPALAQPPLLPQPP-----------------------MAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQ-KVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLPSMPFSAHIQQPPPPTG-QQPTHPPPGQQPPPPQPAKPQQVIQH-----HPSPRHHKSDPYSAGHLREAPSPLMIHSPQMPQFQSLTHQSPPQQNVQPKK---------------------------------QELRPPSVVQPQPLVVVKEEKIH-SPIIRSEPFSTSLRPEPPKHPEN-MKAPVHLPQRPEMKPVDVGRPVIRPPEQSAPPPGAPDKDKQKQEPKTPVAPKK--DLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEHFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQQRQEQ-QQQQQQQ-------AAAVAAASAPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60885-1", "uniprot_id": "BRD4_HUMAN", "id": "O60885-1", "name": "Bromodomain-containing protein 4", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAESGPGTRLRNLPVMGDGLETSQMS-TTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKE------TGTAKPGVSTVPNTTQAS---TPPQTQTPQPNPPP-VQATPHPFPAVTPDLIVQTPVMTVVPPQP----------LQTPPPVPPQPQPPPAPAPQPVQSH----PPIIAATPQPVKTKKGVKRKADTTTPTTIDP-IHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEK---SSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPP----TKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKE--------------EVEENKKSKAKEPPPKKTK---KNNSSNSNVSKKEP--APMKSKPPPTYESEEE---------------DKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPS--LKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQP-----PPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEP-QLPGSVFDPIGHFTQPILHLPQPE--LPPHLPQPP-----EHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPAR---------------------PPAVSPALTQTPLLPQPP-----------------------MAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQ-KVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQ-LQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQG-QQPPHPPPGQQPPPPQPAKPQQVIQH-----HHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKK---------------------------------QELRAASVVQPQPLVVVKEEKIH-SPIIRSEPFSPSLRPEPPKHPES-IKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKK--DLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQ--QQQQQQ-------AAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R5H6-1", "uniprot_id": "BRD4_DANRE", "id": "F1R5H6-1", "name": "Bromodomain-containing protein 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDGLDAVQMSGSSSSQGQPSSQAPSSFNPNPPETSNPTRPKRQTNQLQYLLKVVLKSLWKHQFAWPFHAPVDAVKLNLPDYYKIIKNPMDMGTIKKRLESAFYTSAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKVFLTKISEMPQQEVEISTTAGKGRGRGRRDPDMNMKVGPVLEPLTASPQTRGLSNLTPGPQTRGPPQGPPTLPPQPIVQIQALPPRVPPSLPTIPLHAPQLGPPFSLGPTDCNPPAPIITAVPPPTQTALPPVHIQQSAAPPILQTPISIPNKRKSQKRKADTTTPTANDQ-LNE--SSPAESKSGKTLPRRDNTRPSKLPKKEAPDSQHHWTAAPGTPSPKQQEQLRYCSGIVKDMFAKKHAAYAWPFYKPVDVDTLGLHDYHDIIKHPMDLSTIKDKLETRQYREAQEFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEMLAPAPAPVLHPAPVKTQPVMATASSSDTSSDSSSESESSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQASKPKKKEKEKKEKKKDKHKKKAGVMPALEEILEPPPALKPQGKPKNKDPLPKKSKKLSKKEGGKSNRSMAPPGAAPPTLQPVPGLDTEEDLGLTGGAAMAGMAAGEKCKPMSYEEKRQLSLDINKLPGDKLGRVVHIIQSREPS--LKNSNPDEIEIDFETLKPSTLRELERYVSSCLRKKKKPAVPEKSMEAISAVKTKGTSSDSGSSSESSSSESEDSETGMASKPKKRGR-GEGKKAHHQTTAPGMPLP------QVPLQPQTPALQPSIQLKQQQ--------------PQHPSPAAYMPPP------VTALEPSQLLENPFDPLAHFMHLPHHANDSSSPAPPHLNAHPPGGPVSPETHPFLNQHPILPSPALHNALPQQPSRPSNRAAPLPPKPLQQSTSQQQPPPQQTLVPPQQLQPQQQQPAPPQQQHLPHHPLHAPQQMRPRPLSPPTLTPQGLLSSQPPQMLLEDDEEPVP---SMSLPMYLQHLQPNRLQATPTSLMQSLQSRPQPPGQPSLLQSVQVQSHLPPPQLPVQTQVQPQQPAPHQPSPQ----LSQHQARHMQQLGFPQGPLQTAQTQPGQHKVSMPSTKAQQIIQQQQATQHHSPRQHKADSYNSAHLRDNPSPLMMHSPQIPQYS-LVHQSPSQDKKEPQR------------------------------------------GPSALGGIKEEKLPPSPVMRGEPFSPAMRPESHKHPDSKPTMPGHSQQRADMKPLEMSRPVIRSSEQSGPPPSMQDKEKFKQEPKTPSAPKKVQDVKFKNMGSWASLAQKSSTTPSSGLKSSSDSFEQFRRAAREKEEREKALKAQVEQAEKDRLRKEQEKLRGRDEEDSIEPPRRPLEEPRRRQEPQQVQPPPQQHQTQAQAQTLNPAQSPSASQPTQAPPQSPASSQSALDQQREMARRREQERRRREAMAATIDMNFQSDLMAIFEENLF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q07442-1", "uniprot_id": "BDF2_YEAST", "id": "Q07442-1", "name": "Bromodomain-containing factor 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRTNMDTRHAHSALLAAPQSATANSRSSNSSSESSSNKNNINVGVGDDSGNVSAVSIDDGPHFRDIFHYGHEENYKLASSGITNLNSSSHAHQTLSP-------------ISISNASTPESFPEHPLG---LERETEPALEAEMEAEELPPHQSKYLLSSIKATKRLKDAR-------PFLKPVDPIALN--------IPHYFNYVQTPMDLSLIETKLQGNVYHSVEQVTSDFKTMVDNCLN--------FNGPESSISSMAKRIQKYFEKKLSA---MPPRVLPASALKKTSRNRKKNEDMDSPLVIRRSVSTTNDNIGESGNREGVSGGRPKRTIHPPKSKDLFDIYENSKPK---SKTLQKKFRTCLKILKVLMSKKNSDINFPFLQPVDPIALNLPNYFDVVKNPMDLGTISNNLMNWKYKTIDQFVDDLNLVFYNCFQFNPEGNEVHSMGKKLKELFNFHWLENQDILNEIETDSDLEEDNYS------------SSYSSDDEYDDEDINENDITNPAIQYLEQKLKKMEVELQQLKRQELSKLSKERKRKHLGKTLLRRKAMKHS-----------------------------------------------------------------------------------------VDDLKKSITDKINELSDLEMNGMIRIIKNSLPADEILTSNEDEIEIDLDILDEATIARIYERYFEKKNNNNSKRKLSGNYSTAPTNKKKKTLKFLEKDEIINNNNYSDSEEDSSDSSDSDSD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::: : : : *. . . * *. . .:** .. : ..: . : .* * . : ** .. :: ... *:. *. *: .:.: : * : : .*:* .: : *. * : . : . . . *: * : : . : : : * . . ** : .. :. :. *:: * :* . : . *. . : .*. : **.. . . * . .:::: * *:* :::**:: :** :*** :*.* :* *::*:***:.**..:* :*: ::* *:.*:* **:::** .:** :*.:**:::*:::: : * :* . . ** :*.*. .:.: . :* : * * : ::::. :** . .: .* :*::: * : * :: : *:.:: .**:*.. ::. :::**:. *: : .** ******:: *. :*: .: . . .::.. . . : .: . : . . . ...: .*** : .... . ", "identical_positions": 101, "similar_positions": 221, "identity": "5.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2671", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9P2N7-1", "uniprot_id": "KLH13_HUMAN", "id": "Q9P2N7-1", "name": "Kelch-like protein 13", "aln": "MPLKWKTSSPAIWKFPVPVLKTSRSTPLSPAYISLVEEED-QHMKLSLGGSEMGLSSHLQSSKAGPTRIFTSNTHSSVVLQGFDQLRLEGLLCDVTLMPGDTDDAFPVHRVMMASASDYFKAMFTGGMKEQDLMCIKLHGVSKVGLRKIIDFIYTAKLSLNMDNLQDTLEAASFLQILPVLDFCKVFLISGVTLDNCVEVGRIANTYNLTEVDKYVNSFVLKNFPALLSTGEFLKLPFERLAFVLSSNSLKHCTELELFKATCRWLRLEEPRMDFAAKLMKNIRFPLMTPQELINYVQTVDFMRTDNTCVNLLLEASNYQMMPYMQPVMQSDRTAIRSDTTHLVTLGGVLRQQLVVSKELRMYDEKAHEWKSLAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKWMQVASLNEKRTFFHLSALKGYLYAVGGRNAAGELPTVECYNPRTNEWTYVAKMSEPHYGHAGTVYGGVMYISGGITHDTFQKELMCFDPDTDKWIQKAPMTTVRGLHCMCTVGERLYVIGGNHFRGTSDYDDVLSCEYYSPILDQWTPIAAMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPDKDEWHKVFDLPESLGGIRACTLTVFPPEETTPS--PSRESPLSAP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80TF4-1", "uniprot_id": "KLH13_MOUSE", "id": "Q80TF4-1", "name": "Kelch-like protein 13", "aln": "MPLKWKTSSPAIWKFPVPVLKTSRSTPLSPAYISLVEEED-QHLKLCLG-SEMGLSSHLQSCKAGSTRIFTSNSHSSVVLQGFDQLRLDGLLCDVTLMPGDTDDAYPVHRVMMASASDYFKAMFTGGMKEQELMCIKLHGVSRVGLRKIIDFIYTAKLSLNMDTLQDTLEAASFLQILPVLDFCKVFLISGVTLDNCVEVGRIANTYHLTEVDKYVNSFVLKNFAALLSTGEFLKLPFERLAFVLSSNSLKRCTELDLFKATCRWLRLEEPRMDVAAKLMKNIRFPLMTPQELINYVQTVDFMRTDNTCVNLLLEASNYQMMPFMQPVMQSDRTAIRSDTTRLVTLGGVLRQQLVVSKELRMYDEKTHEWKSLAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKWIQVASLNEKRTFFHLSALKGFLYAVGGRNAAGELPTVECYNPRTNEWTYVAKMNEPHYGHAGTVYGGVMYISGGITHDTFQKELMCFDPDTDKWTQKAPMTTVRGLHCMCTVGDRLYVIGGNHFRGTSDYDDVLSCEYYSPILDQWTPIASMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPEKNEWHKVFDLPESLGGIRACTLTVYPPEEATPS--PSRESPLSGP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IP02-1", "uniprot_id": "A0A0R4IP02_DANRE", "id": "A0A0R4IP02-1", "name": "", "aln": "MPLKWKSGSPVSWKFPVPVLKTSRSSPLSPAYISLVEDDDAQMMKVSLGCSEMGLSSHLQASKTGNTRFFTSNTHSSVVLQGFDQLRIEGLLCDVTLVAGDGDEAFPVHRAMMASSSDYFKAMFTGGMKEQDLMCIKLHGVNRIGLKKIIDFIYTAKLSLNMENLQDTLEAASFLQILPVLDFCKVFLISGVSLDNCVEVGRIANTYNLTEVDKYVNNFILKNFPSLLGTGEFVKLPFERLAFVLSSNSLKHCSELDLFKSACRWLRYEEGRMEYAAKLMRNIRFPLMSPTELINHVQTVDFMRTDNTCVNLLLEASNYQMMPYMQPVMQSERTAIRSDNTHLVTLGGVLRQQLVVSKELRLFDEKAHEWKALAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRYDPRYNKWIQVACLNEKRTFFHLSALKGYLYAVGGRNAAGELATVECYNPRTNEWTYVAKMSEPHYGHAGTVYGGYMYISGGITHDTFQKELMCFDPDADKWTQKAPMTTVRGLHCMCTVGDRLYVIGGNHFRGTSDYDDVLSCEYYSPALDLWTPIAAMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPEKDEWHKVFDLPESLGGIRACTLTVFPPEDLSLAGSPSRESPLSAP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:.**. *************:***********::* * :*:.** **********:.*:* **:****:*************::********:.** *:*:****.****:***************:*********.::**:***************:.****************************:**************:*********.*:****.:**.****:*****************:*:**:***::***** ** **: *****:*******:* ****:***************************:*******:*******.*:*******************::***:****:******************************************:*******:***.***************:*************.******************.************* **********************:*** ******************:*************************** ** *****:***************************************:*:**********************:***: : : ********.*", "identical_positions": 570, "similar_positions": 70, "identity": "86.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2702", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49816-1", "uniprot_id": "TSC2_RAT", "id": "P49816-1", "name": "Tuberin", "aln": "MAKPTSKDSGLKEKFKILLGLGTSRPNPRCAEGKQTEFIITAEILRELSGECGLNNRIRMIGQICDVAKTKK-LEEHAVEALWKAVSDLLQPERPPEARHAVLALLKAIVQGQGDRLGVLRALFFKVIKDY-PSNEDLHERLEVFKALTDNGRHITYLEEELAEFVLQWM----DVGLSSEFLLVLVNLVKFNSCYLDEYIAP-MVHMICLLCIRTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFIITLCRTVNVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMENRSYMEDAPLLRGAVFFVGMALWGAHRLYSLK--NSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRKELQAVTWDILLDIIERLLQQLQNLDSP--------ELRTIVHDLLTTVEELCDQN--EFHGSQERYYELVESYADQRPESSLLNLITYRAQSIHPAKDGWIQNLQLLMERFFRNECRSAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPP----------LELEERDLAVYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYETLISHIQLHYKHGYSLPIASSIRLQAFDFLLLLRADSLHRLGLPN-KDGVVRFSPYCLCDCAELD-RASEKKASGPLSPPTGPPSPVPTGPAVRLGHLPYSLLFRVLLQCLKQETDWKVLKLVLSKLPESLRYKVLIFTSPCSVDQLSSALCSMLSAPKTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYLDKTRQREMVYCLEQGLIYRCASQCVVALAICSVEMPDIIIKALPVLVVKLTHISATASMAIPLLEFLSTLARLP-HLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPYITKGLRSNVLLSFDDTPEKDKFRARSTSLNERPKSLRIARAPKQGLNNSPPVKEFKESCAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSMAQADDNLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGDLQGGSASS-----------------SDPGTHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVG-------VLDTSAPYTPGGPASLGA-------QAAPAARPEKPCAGAQLPAAEKANLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLS--------PFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAAG---------------TAKPPTLPRSNTVASFSSLYQPSCQGQLHRSVSWADSAVVL---------------------EEGSPGEAHVPVEPPELEDFEAALG----TDRHCQRPDAYSRSSSASSQEEKS-HLEELAAGGIPIER---AISSEGARP---TVDLSFQPSQPLS----------KSSSSPELQTLQDILGDLG-----------DKTDIGRLSPEAKVRSQSGILDGEAATWSAPGE------ESRITVPPEGPLPSSSPRSPSG----LRPRGYTISDSAPSRRGKR--VERDNFKSRTAASS-AEKVPGINPSFVFLQLYHSPFCGDESNKPILLPNES--FERSVQLLDQIPSYDTHKIAVLYVGEGQSSSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCD-KKRHLGNDFVSIIYNDSGEDFKLGTIK-GQFNFVHVIITPLDYKCNLLTLQCRKDMEG------LVDTSVAKIVSDRNLSFVARQMALHANMASQVHHRRSNPTDIYPSKWIARLRHIKRLRQRIREEVHYSNPSLPLMHPPAHT---KVPAQAPTEATPTYETGQRKRLISSVDDFTEFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61037-1", "uniprot_id": "TSC2_MOUSE", "id": "Q61037-1", "name": "Tuberin", "aln": "MAKPTSKDSGLKEKFKILLGLGTSRPNPRCAEGKQTEFIITSEILRELSGECGLNNRIRMIGQICDVAKTKK-LEEHAVEALWKAVSDLLQPERPPEARHAVLTLLKAIVQGQGDRLGVLRALFFKVIKDY-PSNEDLHERLEVFKALTDNGRHITYLEEELAEFVLQWM----DVGLSSEFLLVLVNLVKFNSCYLDEYIAS-MVHMICLLCIRTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFIITLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRSYMEDAPLLRGAVFFVGMALWGAHRLYSLK--NSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRKELQAVTWDILLDIIERLLQQLQNLDSP--------ELKTIVHDLLTTVEELCDQN--EFHGSQERYYELVESYADQRPESSLLNLISYRAQSIHPAKDGWIQNLQLLMERFFRNECRSAVAIKVLDVLSFVLLIIRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPP----------PELEERDLAVHSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYESLISHIQLHYKHGYSLPIASSIRLQAFDFLLLLRADSLHRLGLPN-KDGVVRFSPYCLCDCMELD-RASEKKASGPLSPPTGPPSPVPMGPAVRLGYLPYSLLFRVLLQCLKQESDWKVLKLVLSRLPESLRYKVLIFTSPCSVDQLSSALCSMLSAPKTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYLDKTRQREMVYCLEQGLIYRCASQCVVALAICSVEMPDIIIKALPVLVVKLTHISATASMAIPLLEFLSTLARLP-HLYRNFVPEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARAPKQGLNNSPPVKEFKESCAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSMAQADDNLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGDLQGGSDSS-----------------SDPSTHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVG-------VLDTSAPYSPGGSASLGP-------QTAVAAKPEKPPAGAQLPTAEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLS--------PFSSDINNMPLQELSNALMAAERFKEHGHAPVQVIVSATGC----------------TAKPPTLPRSNTVASFSSLYQPSCQGQLHRSVSWADSAMVL---------------------EEGSPGETQVPVEPPELEDFEAALG----TDRHCQRPDTYSRSSSASSQEEKS-HLEELAAGGIPIER---AISSEGARP---AVDLSFQPSQPLS----------KSSSSPELQTLQDILGDLG-----------DKIDIGRLSPEAKVRSQSGILDGEAATWSATGE------ESRITVPPEGPLPSSSPRSPSG----LRPRGYTISDSAPSRRGKR--VERDNFKSRAAASS-AEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNES--FERSVQLLDQIPSYDTHKIAVLYVGEGQSSSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCD-KKRHLGNDFVSIIYNDSGEDFKLGTIKQGQFNFVHVIITPLDYKCNLLTLQCRKDGPACKCEWWRQPGEIVVWALPVVMELTVTILLCHLQMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRIREEVHYSNPSLPLMHPPAHT---KAPAQAP-EATPTYETGQRKRLISSVDDFTEFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49815-1", "uniprot_id": "TSC2_HUMAN", "id": "P49815-1", "name": "Tuberin", "aln": "MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRMIGQICEVAKTKK-FEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLRALFFKVIKDY-PSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWM----DVGLSSEFLLVLVNLVKFNSCYLDEYIAR-MVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVGMALWGAHRLYSLR--NSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDILLNIIERLLQQLQTLDSP--------ELRTIVHDLLTTVEELCDQN--EFHGSQERYFELVERCADQRPESSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPP----------PELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLHRLGLPN-KDGVVRFSPYCVCDYMEPE-RGSEKKTSGPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYKVLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMAVPLLEFLSTLARLP-HLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNSPPVKEFKESSAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQSGPESS-----------------SSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVG-------ALDVPASQFLGSATSPGP-------RTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLS--------PFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAAS---------------TAKPPPLPRSNTVASFSSLYQSSCQGQLHRSVSWADSAVVM---------------------EEGSPGEVPVLVEPPGLEDVEAALG----MDR---RTDAYSRSSSVSSQEEKSLHAEELVGRGIPIER---VVSSEGGRP---SVDLSFQPSQPLS----------KSSSSPELQTLQDILGDPG-----------DKADVGRLSPEVKARSQSGTLDGESAAWSASGE------DSRG--QPEGPLPSSSPRSPSG----LRPRGYTISDSAPSRRGKR--VERDALKSRATASN-AEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCD-KKRHLGNDFVSIVYNDSGEDFKLGTIK-GQFNFVHVIVTPLDYECNLVSLQCRKDMEG------LVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHS---KAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PW15-1", "uniprot_id": "A0A8M9PW15_DANRE", "id": "A0A8M9PW15-1", "name": "Tuberin", "aln": "MNKQPSKES-LRDKFKGIFGLGPTRPHHKQADNKPSEYIITLDILMELTSEYSLNHRIRMVNHVCELAKTKR-FEEHAVEAIWKAVEDLTQPEQPPEARHAVLVLLRAIIQGQGEWLGPLRAYFFKVILDYQPSNEELPERLEVFKALTENGKDITYLEEEIARFVLLWM----ENGLSSDFLHVLVNLVKFNSCYLDENVSL-MVQKICLLCNRTTSSTDIEVALQVLDAVVCYNCLPSDSLTVFIITLCRTVNVKEFCESCWKLMRKVLGTHLGHSAIYTMCRIMEERVYSEDAALLRGAVFFVGMALWGAHRLPALK--NTPTLVLPSFYKAMSCANEVVSYEIVLSITRLIKKYGRELQVVTWDILLSIIDRLLQQIQTMGSP--------DLKVIVYELLSTIEELYEQN--DFHGSSARFFSLVEKCADKRPDASVLTLVSYRAQAIQPAKDGWLQNLLKLMDKFFRNESRTMIRIKVLHILSFVLSTNRQLYEEELIEVVVIPQLGQIAEDRDPSVRKQATQLLVDLAEGCSTHHFSSLLDIIEKVASRPLSCS----------VEGD-RELCVESP-LEDVRTAILGLLDILQSKLYSLPASHASRVYELLISHLQLHYKNKYCSAISGAIRLKVFDFLLLMRADSLHRLGVPN-KDGALRFSPYCHCDPGESEKRVSEKKPTGSVSPPAGSPTPAAPPSSIRTAYLPYSLAFSVLLQCLKTETDWKVLKLVLDKMSCTIQYKVLILTSPCNIDNLCATLCSMVTDRIILERLKKTPDGFSLTDVQLAVVPVLTAITSYHSYLDQLRQRDLVQCLEKGLIYRCAKQCVVALTMCTVEMPDIMIKLLPALIVKLTHISATVAMASPMLEFLSTLVRLP-HLYANFVAEQYVSVFAISLPYTNPSKFNQYIVSLAHHVIAMWFIRCRLPFRKDFVQYITKGLRSNALLPFDDTHEQSSFRARSTSLNERPKSLRTTKVAKQGPSANSPVKDLKDLSAMDAFRSRSISVSEHAVR-RMQTSSTTCSLGSADENAVMQADDALKTVHLELTETCLDMMARYVFSNFSALPKRSPIADFLLSGGPSMTWLVGNKLVTITTSGGSRTQALLGLDMTERHGGGEMTR----------------SDPSLHTRQTKEAPAKLESQSSQQINTNTRTRVRSISGGHALRAGPAQSLSPLVASPEGEYSGPLPPPGPPLDVLSSQRGMEEHPPPSACNPSPPLKHKHSLAEFVPMLTQGWAEIFIRRPSGNTSWLMCLENPPS--------PFSSELGNLPLQELSSVLMAMDGVKEP-PAERPTDVSQPQG------------------KPAPIQRSNTVASLSSLCSSESSGRFHRSISWADSVVME---------------------ESGRSMASVSPAESKEVEEFEAVPSEPIFMNTSTTAPGMMSRSSSTSSQDDDKSTLEEVSEGGIPIDQPPLSLCTPGAQDPELSFTQSSSSSSTLN----------KSSSSPELQTLPEAFSKASSQS-------VDPAPTSKIPTVQACVEAPGESAGSTAGTSCSSSSVSVSSSSTSRMRLEFPPVQTGPLSPTG----HRPRGHTISVSAPSSRRDRKTLERD---ARGGATN-VEKSSGLSPSFVFLQLYHSPFFGNEANKPLLLPKSQ-LIDRAVKVLDQMPPYDTHKIGVVFVGAGQANNEVSILSNEYGSKRYAQFLTGLGKLIHLKDCDPDQIFLGGLDQYGDDGEFTYCWHDDIMQAIFHIATLMPNRESDRGCCN-KKRHIGNDFVVVVYNDSGEDYKLGTIK-GQFNFVEVLIKPLDYESNLVTLQCRKDLEG------LVDTSVAKIVSDRNLPLLVRQMALHANMASLVHQCRANPSDAYASKWLARLRHIKRIRTRAQEEIQ-SRPSHGISLTQGHASMQNKPAHQPPGAAQNPDAGQRKRLVSTVDDFTDFV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VW83-1", "uniprot_id": "Q9VW83_DROME", "id": "Q9VW83-1", "name": "", "aln": "------MNSKDKSKFKLFLKS--------LPAGYVGERTLRPEFERELRPEQPVAQRCRMLKELGDTQLHNFNLDESAITILFNLTNDLIVPNKPAETRQIALSFYKRLIHTQYKNLTIMREKFFLVIQNH-EAREDLRHLLELLDTLTDNGKDITNFEEKIGKFMLLWIPAITEANLLTPYLDILVNLIKFNAAHLDKDILVGIVQNACDLSCSVTVNEIGLQCLTILEMVIGYTIFPSEPLPQCITTLCRTVNHAPYCPSSFKIMKNLLGTQLGYHSMKMMCSILNDRALYDDAHLLRGAVFHLNMNIFGSNIIFQVSPMTYATNVLTAFLRALDSRQVIVTFEVILSVRMVITKR--QLSEIIWDLICDIMSSIVSNIEYYEEVNINKDRLHHLQINFHENIDCIEKLLQQDRSQILGNVERIYDLIERVADRRPEASVLALIEYRSRRVTATRPDWLQVLAQFVRRYYR-MSNVNVRIKTIEALVQIMDQNRACYEEEILSRVVLVHLSHIHLESSVQVRVAVARALSNFATHCDTKRCMDLLDILEALINRPFEHTRHGSSSGEGTLAEVTFGLVNNESEISDIIAAVDGLVKVFAIKLHRLPGIHALKIFNILMDHLELHYERPKIFEHISVVRYKIFAWLLKARANGSYHIGYPEGSTEVVKFSPYLGIDS--------------------------PLLPQAHPTAISIRRVCKLIVRCLEHDTDYQVFQLVIRELPKVLQNKALVQGN--DIEELANTLLKIN-------LVSNNKFKRPTDEFHALVLPAIASLVIYHESLQPQQHYGIITALNSRVLTGIASVCINTMTILILEMPEALMRKLPDVLLQMSKMSDTNALATPVLEFLSLLIHLSKHLFANFTSMHNMYVFAITLPYTKPHRYDHYTVSLAHHVIAGWFLKCKLELRRNCVNYIKSSIQSNAKMLSSDIVNLNSLNEDSSNRK------------------------------------RSTSLTERGSRNNANAWN--------DLEMRPQMNNGLRNFHAELAETCFDFLARHTYSPCPSMPKRLPAAEFLLKDGVSQTWLVGNNLVTITTSGCPSAPARSGLCERCAQLGKAPSISLNSKSLSDAAPPLSPERERRYTKVSLQHSSGNESAGSTELTSSSSSNSAAAGGHPHRQISNSSTASLDALSRRGSNPEALGSALGEGAHTGSNTSLLGNSLSQSSVSMSPSSGSVVQQPVCVRACTGWAEVLVRRPTGNVSWITRIQNPITNDCFGQELPFNNVVSLFLPTAHGGVFGPDNTIQAPPHTLADPEPEPEAEVNAATAPQASALRSRMVAKARALQRQEEIHSVGGNGNGNGNGNGSGNAPSTGGAAAIPIPRVPASGKRGKEAALCGSVSDGEADDDSLAFEDAQSRARNPVRRVNSSPEMSSSWRQSFLTNKPTPLSQEPVKTTADEPQSLLTLKKKTVQYSTKDMRVSCEAIPEEIAGSTPPSQAAALALQPESGTLPPKQHSADDVSSHVAGGSNLQAGGSTLKLGKPPLSPGQPPLLGTGRVTSFGGTSVPQPGALAKSSSSGSNGTNVGVITSDYDNGNNGNGDMMRGRSKTISVVREVNNGNTRPPPASSFRNFGAAKPPINTKLCMNPSFIFMQLYTTGQLGVTDEPLKVGPENS----SAVSLIDLVPPFETHKIGVLYVGQGQCNNEVEILRNSHGSARYVEFLRNIGTLVSLKEAEQNNLFIM-LDRNGADGKFAYIWKDDILQVTFHVATLMPTNLQDDPNCNEKKSHIGNDFVKIIYNESGEEYNLNTIS-GQFNYACVIVEPLDLNSNRVYVKARSEISK------FVCHAEYRIVSDRSAPLLARQMALHANLASLVYQS-VQKKHPYASNWLERLRKLKRLRSKLIEGLNSQQKSGSASSGIGIN-----------------ASAIGSDMDDQRGDFIKYT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :.*** :: . . * : :: ** * : :* **: .: : : ::* *: ::: . ** *::* *:*: .* : : ::: * . * :* ** ** :: :.*:* . **::.:**:**:.** :**::. *:* *: : .* : :* :****:***:.:**: : :*: * *. .. . .* :*: *: *. :*::.*. * *****:* * ..:*:*:::***:**: :: ** ::::* :** *******.:.* ::*:: : : . .* **.:* .*: . : :*::*::**: :*.* :*. : **:: .*:. ::.::: . .*: .:: : :*:* :*: :: *. * :.*:* **:**::*:* *: **:: : .:: .*:* * :: :::* .. : **.:. * :: * ****::. **: :*.:* : . .** .:: * ::* * *:: .****:* : *.:. . : .. :.*: :*: **: :: **: **. ** :::: *:.*::***:. . :* : * :** **:. :::* *: . .::**** * . . : :. ::::**: ::*::*::**: .:. :: *.*: . .:::*. :* .: : . :.: *:*.:::: **. *: :: :: .*:. :: *. *: :::: :***: ::: ** ::::::::* * ::* *:***** * :*. **: **.. : ****:****:* ::::* *.******* **::*:* :*:: * :*...::**. : .* : ..:. *:. : ** *::*: * . :: * : * :: *:..* **:***:*::**:.:* .::*** * .:*** .* : ******:***:*** . : : ** : * : . :.: : : .: ** .. ::. .: . : .* : . . . . .. . . * . ****:::***:**.**: ::** : **.. :. : ...: . : .: : . *. .: *.: : *... . . .*. . . :... ..* . * . :.. : ..... .:: : :.:.: .: . : :. . * . . ..: .*: :: : .. . :.. .* . . .* . . .* * *. *** . . . *. :. :.***:*:*** : * : : *:.. :*.::* :*.::****.*::** **...*: ** *.:** **.:** .:* *: **:.: ::::: ** * **:*:* *:***:*. **:*****.. * *: ** *:***** ::**:***:::*.**. ****:. *:: *** :.* : ::.*.: . : . : * ::** *:: : .. *.*:*: ***::**:* : * .. * . . . : . ** .:.", "identical_positions": 422, "similar_positions": 616, "identity": "21.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2709", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9GZV8-1", "uniprot_id": "PRD14_HUMAN", "id": "Q9GZV8-1", "name": "PR domain zinc finger protein 14", "aln": "MALPRPSEAVPQDKVCYPPESSPQNLAAYYTPFPSYGHYRNSLATVEEDFQPFRQLEAAASAAPAMPPFPFRMAPPLLSPGLGLQREPLYDLPWYSKLPPWYPIPHVPREVPPFLSSSHEYAGASSEDLGHQIIGGDNESGPCCGPDTLIPPPPADASLLPEGLRTSQLLPCSPSKQSEDGPKPSNQEGKSPAR-FQFTEEDLHFVLYGVTPSLEHPASLHHAISGLLVPPDSSGSDSLPQTLDKDSLQLPEGLCLMQTVFGEVPHFGVFCS-SFIAKGVRFGPFQGKVVNASEVKTYGDNSVMWEIFEDGHLSHFIDGKGGTGNWMSYVNCARFPKEQNLVAVQCQGHIFYESCKEIHQNQELLVWYGDCYEKFLDIPVSLQVTEPG-KQPSGPSEESAEGYRCERCGKVFTYKYYRDKHLKYTPCVDKGDRKFPCSLCKRSFEKRDRLRIHILHVHEKHRPHKCSTCGKCFSQSSSLNKHMRVHSGDRPYQCVYCTKRFTASSILRTHIRQHSGEKPFKCKYCGKSFASHAAHDSHVRRSHKEDDGCSCSICGKIFSDQETFYSHMKFHEDY-------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9Q3T6-1", "uniprot_id": "PRD14_MOUSE", "id": "E9Q3T6-1", "name": "PR domain zinc finger protein 14", "aln": "MALPPSGETQSQDKANYLPQSNPHHLTTYYAHAPGYSHFRN-LATTEEEFQPWKLAAAVLESQAMAPLDAFRMTAPLLNPGLAVQSEPLYNLPWY-KLSPWNRIPQFTPEVPRFLDSTEHRSSGSSNQNLVLGGGGGQISGQRWEAENLLLPSPVIASLLPDGIKSS---------QSISVPQTLNQEGKLPFCGFNFTEEELSFVLYGAIASPEHPTDLQHAISGILVPTESSGSNHLHKTLDKDSLQLPEGLCLMQTSFGDVPHFGVFCS-DFIAKGVRFGPFRGRVVNASEVKAHRDNSRMWEIFEDGHLSHFIDGKG-SGNWMSYVNCARFPKEQNLLAVQHQGQIFYESCRDIQRNQELLVWYGNGYEKFLGVPMNLRVTEQGGQQLSESSEESAEGYRCERCGKVFTYKYYRDKHLKYTPCVDKGDRKFPCSLCQRSFEKRDRLRIHILHVHERHRPYLCSTCGKSFSQSSSLNKHMRVHSGDRPYQCVYCTKKFTASSILRTHIRQHSGEKPFKCKHCGKAFASHAAHDSHVRRSHKDNGRSSCDICGKGFLDQEAFYAHMRLHKTC-------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QWQ9-1", "uniprot_id": "F1QWQ9_DANRE", "id": "F1QWQ9-1", "name": "", "aln": "MSVSLSSHPAVRDRS-----------LAVYPSLPG-AHYADVLKSAHSIFHPLKSLGRMVTDAQTIMPFNFSGATPFFSHNSAIFHEQILN------VSNIPYFQHIQPSQSVYNARHEDQSTGSLSD---------------FSSPSSVKSSSALSSPVKD---------------NFSCPQAAHPTPEHART-YSFTEEDLFTVLYG--YSKKQGQNAGHAISGLSFPPSTADRQILP--VDIEGFELPEGISILQTTCGSLSHYGAFADKSTIPKGTRFGPFQGKLVNTSEIKTYDDNTLMWEIFENGRLSHFVDGRGAPGNWMSLVKCARFPEEQNLIAVQCDGQIYYEACKEIRAGQELLVWYGDCYVQFLGIPLTLKEFIDD--SEALPAEDSGEGFKCDRCGKVFAYKYYRDKHLKYTRCVDQGDRKFPCHLCNRSFEKRDRLRIHILHVHEKHRPHKCSVCGKSFSQSSSLNKHMRVHSGERPYKCVYCNKAFTASSILRTHIRQHSGERPFKCKHCGKAFASHAAHDSHVRRTHAKDKQLSCDVCGATFQEAQELKYHMKAHKKRPLLESSVVPPADENALFSTKESLHAQTQLADTFSFPGMTSISSEYRPWN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::. .... :*: : *. *. .*: : * :... *:* : * :.*::. . .: * : : :. : :. . . : .. : .* .: . . : .... :* : : . . *:. : : . :.****:* **** * :: . *****: .*..::. : * :* :.::****:.::** *.:.*:*.*.. . *.**.*****:*::**:**:*:: **: ******:*:****:**:* .***** *:*****:****:*** :*:*:**:*::*: .********: * :**.:*:.*: . . : .:*:*.**::*:******:************ ***:******* **:******************:***: **.***.****************:***:****.* *****************:*****:***:*************:* .: **.:** * : : : **: *: ", "identical_positions": 241, "similar_positions": 159, "identity": "38.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-271", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P02564-1", "uniprot_id": "MYH7_RAT", "id": "P02564-1", "name": "Myosin-7", "aln": "-MADREMAAFGAGAPFLRKSEKERLEAQTRPFDLKKDVFVPDDKEEFVKAKIVSREGGKVTAETENGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKERYASWMIYTYSGLFCVTVNPYKWLPVYNAQVVAAYRGKK------------RSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQ--TPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKK-PELLDMLLITNNPYDYAFFSQGETTVAS-IDDSEEHMATDSAFDVLGFTPEEKNSIYKLTGAIMHFGNMKFKQKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVAYAIGALAKSVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEK---PMGIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRNIK-GKQEAHFSLIHYAGTVDYNILGWLQKNKDPLNETVVGLYQKSSLKLLSNLFANYAGADAP-VDKGK------GKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRKG-----AEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLSRMEFKKLLERRDSLLIIQWNIRAFMGVKN-WPWMKLYFKIKPLLKSAETEKEMANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIVKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLDQDKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTRQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILVEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSTGKSIHELEKIRKQLEAEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA--EKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKNNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKGLNEE----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91Z83-1", "uniprot_id": "MYH7_MOUSE", "id": "Q91Z83-1", "name": "Myosin-7", "aln": "-MADAEMAAFGAAAPFLRKSEKERLEAQTRPFDLKKDVFVPDDKEEFVKAKIVSREGGKVTAETENGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKERYASWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKK------------RSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQ--TPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKK-PELLDMLLITNNPYDYAFISQGETTVAS-IDDSEELMATDSAFDVLGFTPEEKNSIYKLTGAIMHFGNMKFKQKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVSYAIGALAKSVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEK---PMGIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRNVK-GKQEAHFSLVHYAGTVDYNILGWLQKNKDPLNETVVGLYQKSSLKLLSNLFANYAGADAP-ADKGK------GKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRKG-----AEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLSRMEFKKLLERRDSLLIIQWNIRAFMGVKN-WPWMKLYFKIKPLLKSAETEKEMATMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIVKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSTGKSIHELEKIRKQLEAEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA--EKDEEMEQAKRNHLRMVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKGLNEE----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12883-1", "uniprot_id": "MYH7_HUMAN", "id": "P12883-1", "name": "Myosin-7", "aln": "-MGDSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVTAETEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKK------------RSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQ--SPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKK-PELLDMLLITNNPYDYAFISQGETTVAS-IDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEK---PMGIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKPRNIK-GKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANYAGADAP-IEKGK------GKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRKG-----AEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKN-WPWMKLYFKIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA--EKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGTKGLNEE----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02566-1", "uniprot_id": "MYH6_MOUSE", "id": "Q02566-1", "name": "Myosin-6", "aln": "-MTDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEYVKAKVVSREGGKVTAETENGKTVTIKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKK------------RSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRSKKENP-NANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKK-PELLDMLLVTNNPYDYAFVSQGEVSVAS-IDDSEELLATDSAFDVLSFTAEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKSVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLQACIDLIEK---PMGIMSILEEECMFPKASDMTFKAKLYDNHLGKSNNFQKPRNVK-GKQEAHFSLVHYAGTVDYNIMGWLEKNKDPLNETVVGLYQKSSLKLMATLFSTYASADTGDSGKGK------GGKKKGSSFQTVSALHRENLNKLMTNLKTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRKG-----AEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKN-WPWMKLYFKIKPLLKSAETEKEMANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDISQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSSRHDCDLLREQYEEEMEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA--EKDEEMEQAKRNHLRMVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSQANRIASEAQKHLKNSQAHLKDTQLQLDDAVHANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLMRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAK-KMHDEE--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02563-1", "uniprot_id": "MYH6_RAT", "id": "P02563-1", "name": "Myosin-6", "aln": "-MTDAQMADFG-AARYLRKSEKERLEAQTRPFDIRTECFVPDDKEEYVKAKIVSREGGKVTAETENGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKK------------RSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRSKKDNP-NANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKK-PELLDMLLVTNNPYDYAFVSQGEVSVAS-IDDSEELLATDSAFDVLGFTAEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKSVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLQACIDLIEK---PMGIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRNVK-GKQEAHFSLVHYAGTVDYNILGWLEKNKDPLNETVVGLYQKSSLKLMATLFSTYASADTGDSGKGK------GGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSGKG-----AEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQARGQLMRIEFKKMVERRDALLVIQWNIRAFMGVKN-WPWMKLYFKIKPLLKSAETEKEMANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDISQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLTRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSHMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALIWQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEEMEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA--EKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSQANRIASEAQKHLKNAQAHLKDTQLQLDDAVRANDDLKENIAIVERRNTLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLVRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKQKMHDEE--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13533-1", "uniprot_id": "MYH6_HUMAN", "id": "P13533-1", "name": "Myosin-6", "aln": "-MTDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKILSREGGKVIAETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKK------------RSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNA-NANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKK-PELLDMLLVTNNPYDYAFVSQGEVSVAS-IDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEK---PMGIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRNIK-GKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFSSYATADTGDSGKSK------GGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVAIPEGQFIDSRKG-----TEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKN-WPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA--EKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKQKMHDEE--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7H9-1", "uniprot_id": "A0ACD6B7H9_DANRE", "id": "A0ACD6B7H9-1", "name": "", "aln": "-MGDAVMAEFGSAAPFLRKSDKERLEAQTRIFDMKKECFVPDPEVEYVKASITSRDGDKVTVDTEYGKTLTFKECDVHPQNPPKFDKIEDMAMFTFLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYDSSVVKAYRGKK------------RTEAPPHIFSISDNAYQYMLSDRENQSVLITGESGAGKTVNTKRVIQYFASIAAVS--GKKDAA-SEKKGTLEDQIIQANPALEAFGNAKTIRNDNSSRFGKFIRIHFGVSGKLASADIETYLLEKSRVTYQLKAERDYHIFYQILSQKK-PELLEMLLITNNPYDYSYISQGETQVAS-IDDAEELIATDDAFDVLGFTQDEKSGIYKLTGAIMHFGNMKFKQKQREEQAEADGTEDADKVAYLMGLNSADLIKGLCHPRVKVGNEWVTKGQNVQQVYYSIGALAKSVYEKMFLWMVVRINQSLDTKQPRQYFIGVLDIAGFEIFDFNTFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIDWEFIDFGMDLQACIELIEK---PMGIMSILEEECMFPKASDQTFKAKLYDNHLGKNPTFQKPRIVK-GRPEAHFALVHYAGTVDYNISNWLVKNKDPLNETVVGLFQKSTVKLLSFLFAGYSGADSAQDSKGGKG----GGKKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCLIPNETKTPGAMENPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRILNPSANPEGQFIDNKKA-----AEKLLGSLDIDHNQYKLGHTKVFFKAGLLGTLEEMRDDRLALIITGIQARARGILSRLEFQKIVERRDSLLVIQWNVRAFMGVKN-WPWMKLYFKIKPLLKTAETEKEMANMKEEFTKLKEAYAKSEARKKELEEKMVSLLQEKNDLQLAVQSEQDNLVDAEERCEGLIKSKIQLEAKAKELTERLEDEEEMNAELVAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAALDEIIAKLTKEKKALQEAHQQTLDDLQSEEDKVNTLTKAKAKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLTQESIMDLENDKQQMEEKLKKKDFEISQLNSKIEDEQALGAQLQKKLKELQARIEELEEELEAERAARAKVEKQRADLSRELEEISERLEEAGGATAAQIEMNKKREAEFQKLRRDLEEATLQHEATAATLRKKHADSVADLGEQIDNLQRVKQKLEKEKSELKLELDDVVSNMEQIVKSKSNLEKMCRTLEDQMSEYRTKAEEGQRTINDFTMQKAKLQTENGELSRQLEEKDSLVSQLTRGKQSYTQQIEDLKRQLEEEVKAKNALAHAVQSARHDSDLLREQFEEEQEAKAELQRSLSKTNSEVAQWRTKYETDAIQRTEELEDAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKVLAEWKQKYEESQTELESAQKESRSLSTELFKLKNSYEEVLDQLETMKRENKNLQEEISDLTEQLGETGKSIHELEKIRKQLEQEKAEIQTALEEAEGSLEHEEGKILRAQLEFNQVKADIERKLS--EKDEEMEQAKRNQQRVVDTLQSSLESETRSRNEALRLKKKMEGDLNEMEIQLSQANRQASEAQKQLKSLHGHVKDSQMQLDDALRGNDDLKENIAIVERRNNLLQAELDELRSLVEQTERGRKLAEQELMDVSERVQLLHAQNTSLLNQKKKLEGDNTQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIAMKGGKKQVQKLEARVRELENEVELEQRKASESVKGVRKYERRIKELTYQTEEDRKNLARLQDLVDKLQLKVKSYKRAAEEAEEQANSNLGKFRKLQHELDEAEERADIAESQVNKMRAKSRDSGPKKGHDEE---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P05661-3", "uniprot_id": "MYSA_DROME", "id": "P05661-3", "name": "Myosin heavy chain, muscle", "aln": "MPKPVANQEDEDPTPYLFVSLEQRRIDQSKPYDSKKSCWIPDEKEGYLLGEIKATKGDIVSVGLQGGETRDLKKDLLQQVNPPKYEKAEDMSNLTYLNDASVLHNLRQRYYNKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRGKR------------RNEVPPHIFAISDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGASK---KTDEA-AKSKGSLEDQVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAGADIETYLLEKARVISQQSLERSYHIFYQIMSGSV-PGVKDICLLTDNIYDYHIVSQGKVTVAS-IDDAEEFSLTDQAFDILGFTKQEKEDVYRITAAVMHMGGMKFKQRGREEQAEQDGEEEGGRVSKLFGCDTAELYKNLLKPRIKVGNEFVTQGRNVQQVTNSIGALCKGVFDRLFKWLVKKCNETLDTQQKRQHFIGVLDIAGFEIFEYNGFEQLCINFTNEKLQQFFNHHMFVLEQEEYKREGIDWAFIDFGMDLLACIDLIEK---PMGILSILEEESMFPKATDQTFSEKLTNTHLGKSAPFQKPKPPKPGQQAAHFAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKKSQNKLLIEIFADHAGQSGGGEQAKG------GRGKKGGGFATVSSAYKEQLNSLMTTLRSTQPHFVRCIIPNEMKQPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRYKIMCPKLLQG--VEKDKKA-----TEIIIKFIDLPEDQYRLGNTKVFFRAGVLGQMEEFRDERLGKIMSWMQAWARGYLSRKGFKKLQEQRVALKVVQRNLRKYLQLRT-WPWYKLWQKVKPLLNVSRIEDEIARLEEKAKKAEELHAAEVKVRKELEALNAKLLAEKTALLDSLSGEKGALQDYQERNAKLTAQKNDLENQLRDIQERLTQEEDARNQLFQQKKKADQEISGLKKDIEDLELNVQKAEQDKATKDHQIRNLNDEIAHQDELINKLNKEKKMQGETNQKTGEELQAAEDKINHLNKVKAKLEQTLDELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKELSSITAKLEDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEELGERLEEAGGATSAQIELNKKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNKLKAKAEKEKNEYYGQLNDLRAGVDHITNEKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSIENSDLLRQLEEAESQVSQLSKIKISLTTQLEDTKRLADEESRERATLLGKFRNLEHDLDNLREQVEEEAEGKADLQRQLSKANAEAQVWRSKYESDGVARSEELEEAKRKLQARLAEAEETIESLNQKCIGLEKTKQRLSTEVEDLQLEVDRANAIANAAEKKQKAFDKIIGEWKLKVDDLAAELDASQKECRNYSTELFRLKGAYEEGQEQLEAVRRENKNLADEVKDLLDQIGEGGRNIHEIEKARKRLEAEKDELQAALEEAEAALEQEENKVLRAQLELSQVRQEIDRRIQ--EKEEEFENTRKNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQIKELQVRLDEAEANALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRKNHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQAISKFRAKGRAGSVGRGASPAPRATSVRPQFDGLAFPPRFDLAPENEF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08964-1", "uniprot_id": "MYO1_YEAST", "id": "P08964-1", "name": "Myosin-1", "aln": "--MTGGQSCSSNMIVWIPDEKEVFVKGELMSTDINKNKFTGQEEQIGIVHPLDS---------TEVSNLVQVRISDVFPVNPSTFDKVENMSELTHLNEPSVLYNLEKRYDCDLIYTYSGLFLVAINPYHNLNLYSEDHINLYHNKHNRLSKSRLDENSHEKLPPHIFAIAEEAYENLLSEGKDQSILVTGESGAGKTENTKKILQYLASITSGSPSNIAPVSGSSIVESFEMKILQSNPILESFGNAQTVRNNNSSRFGKFIKIEFNEHGMINGAHIEWYLLEKSRIVHQNSKERNYHIFYQLLSGLDDSELKNLRLKSRNVKDYKILSNSNQDIIPGINDVENFKELLSALNIIGFSKDQIRWIFQVVAIILLIGNIEFVSDRAEQASFKN---DVSAICSNLGVDEKDFQTAILRPRSKAGKEWVSQSKNSQQAKFILNALSRNLYERLFGYIVDMINKNLDHGSATLNYIGLLDIAGFEIFENNSFEQLCINYTNEKLQQFFNNHMFVLEQSEYLKENIQWDYIDYGKDLQLTIDLIESKGPPTGVLPLLDEEAVLPKSTDESFYSKLISTWDQNSSKFKRSRLKN------GFILKHYAGDVEYTVEGWLSKNKDPLNDNLLSLLSSSQNDIISKLFQPEGEKSSSAGVEANISNQEVKKSARTSTFKTTSSRHREQQITLLNQLASTHPHFVRCIIPNNVKKVKTFNRRLILDQLRCNGVLEGIRLAREGYPNRIAFQEFFQRYRILYPENSTTTTFSSKLKASTKQNCEFLLTSLQLDTKVYKIGNTKLFFKAGVLADLEKQKDVKLNNIMIKLTATIRGYTVRKEITYHLQKLKKTRVIGNTFRLYNRLVKEDPWFNLFIRIKPLLTSSNDMTRTKKFNEQINKLKNDLQEMESKKKFLEEKNQKTVNELENTQDLLNQEKENLRKNESLLNRVKTSSETLQKQFDDLVSEKDEISREKLEVAQNLEEAHQKIQGLQETIREREATLEKLHSKNNELIKQISDLNCDISKEQSSQSLIKESKLKLENEIKRLKDVINSKEEEIKSFNDKLSSSEEDLDIKLVTLEKNCNIAMSRLQSLVTENSDLRSKNE---NFKKEKAALNNQLKNKESELLKMKEKIDNHKKELATFSKQRDDAVSEHGKITAELKETRIQLTEYKSNYQKIKEEYSNFQRETKEQ-----EQKKRNSLVESLNDSKIKELEARLSQEISLNQYLNKRISGNSVETNISSTRRSTSYSDDPLDKEDIIKKYYDLQLAFTEITRNLENEIEEKKNLISRLRFTETRLASSSFEDQKIKAQMKKLKKLIQDMDPSIP-LDSILNEPLDNCPDKESDINKLMLEVDYLKRQLDIETRAHYDAENAISALHSKFRKIQGESSLSSSDIYKLKFEASEERVKSLEDKLKTMP--------LRDRTNLPVGDIIKNRDSISKYEEEIRYYKLENYKLQEILNESNGKLSQLTLDLRQSKSKEALLSEQLDRLQKDLESTERQKELLSSTIKQQKQQFENCMDDLQGNELRLREHIHALKQAEEDVKNMASIIEKLKTQNKQKEKLIWEREMERNDSDMQLQETLLELKRVQDVKKILSDDLAHLKERLSAVEDRSQYTDEINRLKEELNCSLKAETNLKKEFATLKYKLETSTNDSEAKISDLLKQLDHYTKVVEMLNNEKDAISLAEKELY--------------QKYEALNTECESLKGKIVSLTKIKQELESDLNQKTDALQISNAALSSSTQKNKEITEKIKYLEETLQLQMEQNSRNGELVKTLQASCNGYKDKFDDEKQKNIDLYEENQTLQKLNTDLQLQLKNLHERLSDTTEK--NAWLSKIHELENMVSLETDLKYEEMKKNKSLERAVEELQTKNSQQTDVIELANKNRSEFEEATLKYEAQISDLEKYISQQELEMKKSIRDNSSYRDKVQEMAQEIEFWKSRYESTMIGSKNIDSNNAQSKIFS------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . : : * ... : : : : : : : .: .: : **..::* *:*: :*.*::.:**.**..** :******** *::***: :* *:.*: : : *****:*:: ** :*:: :**:*:********* ***::: *:* : : ::* :::*:** **:****:*:**:*********:*.*. * : .*.** *****:*: * . **.******::* . : :: * : * ** .*:.: : . *:* *: .*::::.*: :: ::::.. :: *.::* *: : : : . . :* : :: . : :** *.*:*:*::.:. **. .**.: :::::* ::* * .*: . :**:*********: * *******:**********:*******.** :*.*:* :**:* ** *:***. * *::.:*:**.::**::* :* ** .. :. *::.: : * : **** *.*.: .** *******:.:: ..* .:: :* . . : . * *.*: ::*: .*:. * :*:******:***: * ..: *::.** *********:.*:*:***: : :* **:*: * . .. *. * :: ::: . *::*:**:**:**:*. :*: :* :* *: : * ** * :: :: ..* : : . ** :*: ::****. :. . ::*: : :: :* ** . : * :. *: * . :. : .. *: : :: .. : . . :: : .: .:: . *:. * : * .: * ...: ::: :*. ::: :. :.:.* : :: : :: *:::: :.. . *: :* :*::: :: . :: . :.**: .:* :::.:* ::: ::.*: :: . ::::.: .:: .: :. :: *:: * :: :. .: .* .:: .. :* * : *. *: .. ::** *. : *.*: . .: . . . . :*.: : *: . .* . : : * . : . . :.: . **. :: .: :: : : :::. : : . .: . *:.: .: .: . : * : *. * * * : * * . : . . *: : . * .* ::.:*. . : .. . : : :*:::::: . *: : : * :*: :.*: . . :: . :.: ::: . . :.:::. .*: * * : :::: *:. :: *.* . : :: : . *: .: : * : :: **.:*:. : * :* *:* . *: * :.. : . * :: : . . .: :: *: * :. : : . : :: *.:* : : :: : :* :::: . *. :: ::: . * .*. ... ::: *:: . .: ::: .:** :*.: . . :* : :::***. :. * : * :. ** ::** :..:: . :. .::: *: .: *: : :::* :: .. .::.: . :. ::: . ", "identical_positions": 374, "similar_positions": 675, "identity": "18.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2711", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LMZ8-1", "uniprot_id": "PSD11_RAT", "id": "F1LMZ8-1", "name": "26S proteasome non-ATPase regulatory subunit 11", "aln": "MAAAAVVEFQRAQSLLSTDR-EASIDILHSIVKRDIQ--------ENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSEKRTFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALLVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSP----KAITSLKYMLLCKIMLNTPEDVQALVSGKLALR-YAGRQTEALKCVAQASKNRSLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIKLSKADVERKLSQMILDKKFHGILDQGEGVLIIFDEPPVDKTYEAALETIQNMSKVVDSLYNKAKKLT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00231-1", "uniprot_id": "PSD11_HUMAN", "id": "O00231-1", "name": "26S proteasome non-ATPase regulatory subunit 11", "aln": "MAAAAVVEFQRAQSLLSTDR-EASIDILHSIVKRDIQ--------ENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSEKRTFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALLVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSP----KAITSLKYMLLCKIMLNTPEDVQALVSGKLALR-YAGRQTEALKCVAQASKNRSLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIKLSKADVERKLSQMILDKKFHGILDQGEGVLIIFDEPPVDKTYEAALETIQNMSKVVDSLYNKAKKLT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BG32-1", "uniprot_id": "PSD11_MOUSE", "id": "Q8BG32-1", "name": "26S proteasome non-ATPase regulatory subunit 11", "aln": "MAAAAVVEFQRAQSLLSTDR-EASIDILHSIVKRDIQ--------ENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSEKRTFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALLVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSP----KAITSLKYMLLCKIMLNTPEDVQALVSGKLALR-YAGRQTEALKCVAQASKNRSLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIKLSKADVERKLSQMILDKKFHGILDQGEGVLIIFDEPPVDKTYEAALETIQNMSKVVDSLYSKAKKLT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F6P3G4-1", "uniprot_id": "PS11A_DANRE", "id": "F6P3G4-1", "name": "26S proteasome non-ATPase regulatory subunit 11A", "aln": "-MAATAVEFQRAQSLLSTDR-NASIDILHAIVKRDVQ--------DDDEEAVRVKEQSILELGGLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDMFLDMEAATGQEVELCLECIEWAKSEKRTFLRQALEARLVSLYFDTKRYQEALQLGSQLLQELKKMDDKALLVELQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQAALDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSP----RAITALKYMLLCKIMLNSPEDVQSLISGKLALR-YAGRQTEALKCVAQASKNRSLADFEKALTEYKAELRDDPIISTHLTKLYDNLLEQNLIRVIEPFSRVQIEHISELIKLSKGDVERKLSQMILDQKFHGILDQGEGVLIVFDEPPVDKTYEASLETIQNMSKVVDSLYNKAKKLT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KLV9-1", "uniprot_id": "PSD11_DROME", "id": "Q7KLV9-1", "name": "26S proteasome non-ATPase regulatory subunit 11", "aln": "--MAGATLFERAQALSSVNR-EEQDSSLLNKLVRDQEG------AENDEERIRIKEQGILQQGELYKQEGKAKELADLIKVTRPFLSSISKAKAAKLVRSLVDMFLDMDAGTGIEVQLCKDCIEWAKQEKRTFLRQSLEARLIALYFDTALYTEALALGAQLLRELKKLDDKNLLVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKVQGALDLQSGILHAADERDFKTAFSYFYEAFEGFDSVDSV----KALTSLKYMLLCKIMLGQSDDVNQLVSGKLAIT-YSGRDIDAMKSVAEASHKRSLADFQAALKEYKKELAEDVIVQAHLGTLYDTMLEQNLCRIIEPYSRVQVAHVAESIQLPMPQVEKKLSQMILDKKFSGILDQGEGVLIVFEETPVDKTYERVLETIQSMGKVVDTLYQKAKKLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12377-1", "uniprot_id": "RPN6_YEAST", "id": "Q12377-1", "name": "26S proteasome regulatory subunit RPN6", "aln": "-MSLPGSKLEEARRLVNEKQYNEAEQVYLSLLDKDSSQSSAAAGASVDDKRRNEQETSILELGQLYVTMGAKDKLREFIPHSTEYMMQFAKSKTVKVLKTLIEKFEQVPDSLDDQIFVCEKSIEFAKREKRVFLKHSLSIKLATLHYQKKQYKDSLALINDLLREFKKLDDKPSLVDVHLLESKVYHKLRNLAKSKASLTAARTAANSIYCPTQTVAELDLMSGILHCED-KDYKTAFSYFFESFESYHNLTTHNSYEKACQVLKYMLLSKIMLNLIDDVKNILNAKYTKETYQSRGIDAMKAVAEAYNNRSLLDFNTALKQYEKELMGDELTRSHFNALYDTLLESNLCKIIEPFECVEISHISKIIGLDTQQVEGKLSQMILDKIFYGVLDQGNGWLYVYETPNQDATYDSALELVGQLNKVVDQLFEKASVLY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.*: * . .: : . : :* . . *:: . :* .**: * * * :* :: :: .::*:*:.:::::*:: * :: . . :: :* ..**:** ***.**:::*. :* :*:::. * ::* * :**:*:**:*** **:::*****.** * **.*::*:**:***:**:****.: . **: ***:*. : :*:***:***:*:**.:..: : :* ******.****. :**: ::..* : * .* :*:*.**:* ::*** **: **.:*. ** * : :*: ***.:**.** ::***:. *:: *::. * * :** ********: * *:****:* * ::: . * **: ** : .:.**** *:.**. * ", "identical_positions": 158, "similar_positions": 145, "identity": "36.24%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2712", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80TL7-1", "uniprot_id": "MON2_MOUSE", "id": "Q80TL7-1", "name": "Protein MON2 homolog", "aln": "----MSCTNSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSETAAGNIINMLWQLMENSLE-ELKLLQTVLVLLTTNTVVHDEALSKAIVLCFR--LHFT-KDNITNNTAAATVRQVVTVVFERMVAEDDRHRD-IEPPVPIQGNSNRRSVSTLRPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTS--SSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDSDK--PQWLRAVAVESIHRLCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPPTGN-PATANQAGNNNAGGPASAPANSGVVGVGGGVTLLPAFEYRGAWIPILTVTVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITTMIEGELGEVEAEGPSVTEGASS--QSSERRDEQAASDPMDQETVSRAVWEEMVSACWCGLLAALSLLLDAS-TDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNATTAATLSNKSYSIQGQ---SVMMISPSS----ESHQQVVAVGQPLAVQ------PQGTVMLTSKNIQCMRTLLNLAHCHGAVLG-TSWQLVLATLQHLVWILGLKPSSGGALKPG-RAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVN---------------------MHRIEILWRPLTGHLLEKVCQHPNSR--MREWGAEALTSLIRAGLTFS-----HEPPLPQNQRLQLLLLNPLKEMSN-----------------INHPDIRLKQLECVLQILQSQGDSLGPGWPLVLGVMG------------AIRNDQGES------------LIRTAFQCLQLVVTDFLPTMPCSCLQIVVDVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGETIEKELNKEEAAQQKQAEEKGVSLNRP----FHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHSTWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSRAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPVRDSEKPEPP-AVSVPVPVLLGNLSGPGLSRPFVRTDSIGEKLGRCGS-ETPVVT--DELEDLKLWWAAWNTWHRTGSESTEPPSS-VDELT-------------FIPSQPFLTALVQIFPALYQHIKAG--FSMADLQKLGVILHSAVSVPISSDASPFILP--SYTEAVLTSLQEAVLTALDVLQKAICVGPENMQIMYPAIFDQLLAFVEFSCKPPQYGQLETKHIANAKYNQIQLFAPAEWVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQNI-IKTLRVPLSLKYSCPSESTWKLAVASLLKVLSIGLPVARQHASSGKFDSMWPELASTLEDFLFTKSIP-PDNLSIQEFQRNESIDVEVVQLISAEILPYANLIPKAFVGQMMTMLNKGSIHSQPCSFTEAEIDIRLREEFSKMCFETLLQFSFSNKVTTPQ------------------EGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTQPENVDGNTWSQVIALYPTLVECITCSSSDVGSALKEALAPFKDFMQPPASR----------VQNGES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZCG3-1", "uniprot_id": "D3ZCG3_RAT", "id": "D3ZCG3-1", "name": "Protein MON2 homolog", "aln": "----MSCTNSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGCGTKEPKVTQLCLAAIQRLMSHEVVSEAAAGNIINMLWQLMENSLE-ELKLLQTVLVLLTTNTVVHDEALSKAIVLCFR--LHFT-KDNITNNTAAATVRQVVTVVFERMVAEDDRHRD-IDPPVLIQGNSNRRSVSTLRPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSGTS--SSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDADK--PQWLRAVAVESIHRLCVQPRLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPPTGN-PAAANQAGNNNAGGPASAPANSGVVGIGAGVTLLPAFEYRGAWIPILTITVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITTMIEGELGEVETECPTVTEGASS--QSSERRDEQSESDHMDQETVSRAVWEEMVSACWCGLLAALSLLLDAS-TDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNATTAATLSNKSYSIQGQ---SVMMISPSS----ESHQQVVAVGQPLAVQ------PQGTVMLTSKNIQCMRTLLNLAHCHGAVLG-TSWQLVLATLQHLVWILGLKPSSGGALKPG-RAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVN---------------------MHRIEILWRPLTGHLLEKVCQHPNSR--MREWGAEALTSLIKAGLTFN-----HEPPLSQNQRLQLLLLNPLKEMSN-----------------INHPDIRLKQLECVLQILQSQGDSLGPGWPLVLGVMG------------AIRNDQGES------------LIRTAFQCLQLVVTDFLPTMPCSCLQIVVDVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGETIEKELNKEEAAQQKQAEEKGVSLNRP----FHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHATWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSRAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPARDSEKPETP-VGTVPVPVLIGNISGQGLSRPFVRTDSIGEKLGRCSS-EPPVVT--DEAEDLKLWWAAWNTWHRTGSESTEPPST-FDELT-------------FIPSQPFLTALIQIFPALYQHIKAG--FSMADLQKLGVILHSAVSVPISSDASPFILP--SYTEAVLTSLQEAVLTALDVLQKAICVGPENMQIMYPAIFEQLLAFVEFSCKPPQYGQLETKHIANAKHNQIQLFAPAEWVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQSI-IKTLRVPLSLKYSCPSESTWKLAVASLLKVLSIGLPVARQHASSGKFDSMWPELASTLEDFLFTKSIP-PDNLSIQEFQRNESIDVEVVQLISAEILPYANLIPKAFVAQMMTMLNRGSIHSQPSSFTEAEIDIRLREEFSKMCFETLLQFSFSNKVTTPQ------------------EGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTQPENVDGNTWAQVIALYPTLVECITCSSSDVCSALKEALVPFKDFMQPPASK----------VQNGES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z3U7-1", "uniprot_id": "MON2_HUMAN", "id": "Q7Z3U7-1", "name": "Protein MON2 homolog", "aln": "----MSGTSSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSETAAGNIINMLWQLMENSLE-ELKLLQTVLVLLTTNTVVHDEALSKAIVLCFR--LHFT-KDNITNNTAAATVRQVVTVVFERMVAEDERHRDIIEQPVLVQGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTS--SSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDADK--PQWLRAVAVESIHRFCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPPTGN-PATSNQAGNNNLGGSVSAPANSGMVGIGGGVTLLPAFEYRGTWIPILTITVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITSMIEGELGELETECQTTTEEGSSPTQSTEQQDLQSTSDQMDKEIVSRAVWEEMVNACWCGLLAALSLLLDAS-TDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNTTTAATLSNKSYSVQGQ---SVMMISPSS----ESHQQVVAVGQPLAVQ------PQGTVMLTSKNIQCMRTLLNLAHCHGAVLG-TSWQLVLATLQHLVWILGLKPSSGGALKPG-RAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVN---------------------MHRIEILWRPLTGHLLE-VCQHPNSR--MREWGAEALTSLIKAGLTFN-----HDPPLSQNQRLQLLLLNPLKEMSN-----------------INHPDIRLKQLECVLQILQSQGDSLGPGWPLVLGVMG------------AIRNDQGES------------LIRTAFQCLQLVVTDFLPTMPCTCLQIVVDVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGETIEKELNKEEAAQQKQAEEKGVVLNRP----FHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHSTWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSRAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPVRDSDKPETPPVVNVPVPVLIGPISG--MSRPFVRTDSIGEKLGRYSSSEPPIVT--DELEDLNLWWAAWNTWYRIGSESTKPPIT-FDKLT-------------FIPSQPFLTALIQIFPALYQHIKTG--FNMDDLQKLGVILHSAISVPISSDASPFILP--SYTEAVLTSLQEAVLTALDVLQKAICVGPENMQIMYPAIFDQLLAFVEFSCKPPQYGQLETKHIANAKYNQIQLFAPAEWVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQNI-IKTLRVPLSLKYSCPSESTWKLAVSSLLRVLSIGLPVARQHASSGKFDSMWPELANTFEDFLFTKSIP-PDNLSIQEFQRNENIDVEVVQLISNEILPYANFIPKEFVGQIMTMLNKGSIHSQSSSFTEAEIDIRLREEFSKMCFETLLQFSFSNKVTTPQ------------------EGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTQPENVDGNTWAQVIALYPTLVECITCSSSEVCSALKEALVPFKDFMQPPASR----------VQNGES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P6K6-1", "uniprot_id": "A0A8M9P6K6_DANRE", "id": "A0A8M9P6K6-1", "name": "Protein MON2 homolog", "aln": "-MSLKMSTSSPEAVKKLLENMQADLRSLSMECKKKFPPVKEAAESGIVKIKTIAARNTDILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSEAAAGNIINMLWQLMENGLE-ELKLLQTVLVLLTTNTIVHDEVLSKAIVLCFR--LHFT-KDNITNNTAAATVRQVVTVVFERMVAEDERFKGLNEEPPAVQGNCNRRSVSTLRPSAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSSSS-ASPAPVEKPYFPICMRLLRVVSVLIKHFYSLLVTECEIFLSLLVKFLDGEK--PQWLRAVAVESVHRLCVQPHLLRSFCQSYDMKPHSTKVFRDIVNALGSFIQSLFILPSAGNTSSTSTPAGGSVSSSQASGPGGPGLTGAGGALTTQAAFEYRGTWIPLMNVSVQGSAKATYLEMLDKVEPPSIPEGYAMSVAFSALLDLVRGITNMIDRELLRQE--------------QQEAMREEEEPVSPPAQEPLAAEVWQEMVNACWCGLLAALSLLLDAS-TDETATENILKAELSMASLCGRLGLVTPRDAFITAVCKASLPPHYALTILSSS-ASSLTNKVYSIQGQ---SVQMVSPSS----ESHQQVVAVGQPLSAQ------PQGTVVLTAKNIQCMRTLLNLAHCHGAHLG-TSWQLVLATLQHLVWILGLKPAPGGVLKPG-RAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSMEAMEMAYGTNKEPSLFAVAKLLETGLVN---------------------MDRIEILWRPLTAHLLE-VCQHPNAR--MREWGAEAITSLIKAGLSYK-----HDPPLSQNQRLQLLLLNPLKELSN-----------------VLHADIRQKQLECVLQILQNQGDSLGPGWPLVLGVIG------------AIRNDQGES------------LIRTAFQCLQLVVTDFLPTMPCMCLQIVVDVAGSFGLQNQELNISLTSIGLLWNISDYFFQRGEAITEELDKEEAVLLKQAQDKGEPLNRP----FHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTMFSTIAAHGTLLQPPTWNIVVWKVLFHLLDCVRKSSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQQLGDFFKAWEVLLDHIQSAALSKNNEVSLAALKSFQEILQLVTPIKDTDKPDALSAIDVPS-VLMESLQGSGPGRPLVRSDSLAERLAQRYAAQPSLPPPGEELDDSALWWSAWNTWYRVGTECTRPPSGGTDKLV-------------FVPSQPFLTALIQIFPALYQHIAGG--FSMEDLKKLGVILHGAVSVPISSDSSPFILP--SYTEAVLTSLQEAVLTALDVLQKAICVSSENLQVMYPAIFEQLLLFVEFSCKPPQYGKMETKHVANAKYNQIQLFAPAEWVALNYVPFAERSLEVVVDLYHKTACHKAVINEKVLQNI-IKTVRIPLGLKYACPAESTWKLAVSSLLKVLSIGLPVARQQASSGKFDTMWPELANAFEDFLFTKSTP-PDNLSIQEFQRNEAVDVEVVQLISSEILPFANFIPKEFVGRIMSMLNKGSIHSQSSSFTEAEMDMRMREDFSKVCFETLLQFSFSNKVSTPQ------------------EGFISRMALSVLLQRAQDVLRRYVEDERLSGRCPLPRQQVTEIIFVLKAISTLMDSLKKTQPENVDGNVWAQVIALYPTLVECITCTSPEVSSALKDALGPFKDFMQPPVSK----------VQNGES", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLT1-1", "uniprot_id": "MON2_DROME", "id": "Q9VLT1-1", "name": "Protein MON2 homolog", "aln": "MSFVGGGGCGGQDVHKFVEALQADFKTLSLETKKKYPQIKEACEEAISKLCTAGSSQ---QNSVYYTVNQILYPLVQGCETKDLKIIKFCLGMMQRLITQQVVDQKGALYITNALWTLMENNIE-EVKVLQTVTLLLTTNTVVHGDTLAKALVLCFR--LHYA-KNPTIVNTAGATIRQLVSLVFERVYLEKDSVSSLQQQQSSGSPAEGEGGNQDVQTFASDAFLLFQDLVQLVNADQPYWLLGMTEMTRTFGLELLEAVLTNFSAVFHESNDFRLLLKERVCALVIKLFSPNVKHRQLPAPSNGNAPVPAEKPYFPISMRLLRLVAILIQKYHTILVTECEIFLSLIIKFLDPDK--PAWQRALALEVIHKLVTRSSLIAFFCKSYDLKNHATNIVHDMIAAMGSYIRYSLIN--------ASAMLNGQQNGVANSLTAMSGSNQCG--------FMFRGAYLPLVATYAPGVSKAVYLEMLDKIDASNIPDSYGISVGHAILLDMTRSIGGVIQRTP-----------------------ELHPSHNTAVITEEEHKPLCLQLVNSSWSALLSAFIPLVETS-IDEATTENILKAMQNYAALCGMLEQLQPRDAFIMAMCRASFPPHYAMSIFANTTQSDGDLRCHTRSGSQDLSSQFINSCSGDAGDFRPQIVAVGTPLPSASLPHSVMQAPVMLTNKNLQCMRAILFLAHNNGGILG-TSWHIVLQTLQHLVWILGLKPSTGGSLQAMPKPAVEANVGIQTAVMADLPVLSQMLSQLFESSQYLDDVALHHLIDALCKLSHEAMELAYAN-REPSLFAVAKLLETGLVN---------------------MPRIKVLWRPLTNHLLE-VCQHRHIR--MREWGVEAITYLVKSALQFK-----HKTPLKENMELQTMLLSPLSELST-----------------VLHADVRQRQLDCVLQILNTAGEILSFGWPAIIEIIG------------AVNEHHGEP------------LIRTAFQCLQLVITDFLTVMPWRCLPLCISTAAKFGSQTQELNISLTAIGLMWNISDFFNQ----------NQDKLMSTQLQDVSILPDFPG---TVKMPQFDKLWMCLYAKLGELCVDLRPAVRKSAGQTLFSTISAHGSLLNPPTWQALVWQVLFPLLDNVRALSSSASNEKVDASG-NILIHHSRNTAQKQWAETQVLTLSGVCRVFNTKRELLQMLGDFERAWSLILEFIQNAALSKNGEVSLAALKSLQEIMYHNTAER--------------------------TERALKDPQTAQE-------------------QDEEIWTIAWNIWLSIGMESTKMSTSTSAKLQQQNSNGAETQEDFYIPSQAFLTALIQIFPAIFQHIQVK--FTAADFDKFCTVLTNAVCIPVQTDAVPYIMS--TVSDTLLTPLHDGILDCMELIQKEATKPDSHISQLIPAIFRQLLIFSKFACAPPTFQQSVEHKYAKSSG-HYANNASVEVVSMNYIPFGEKSISICVKLYQTTATEDSVVQEQILHDI-VKALRTPLAMKYKCLSSSTWKLAISSLISVLHTGLKVAR--AKPQHFASLWDDLADTLDKFLFPASVCTIEDRGLEEIVLDETIDCQVIELLRDEVLPHSHEMPHQFIMQIVVLLNKGSIHSASDTNICYESDWKLREIFAKTCFETLLQFSLLEDHANTNNNRLNANVLTAGAAGAGGKDFAGRLAVTALLHRFQEVLKRFNDDERQSGKCPLPRFRLSEISFVLKAIATLVVSMKKAPASKVNKPAWDQLIGLYPYLVDCTTTTSPEVSRSLREALLQYTDLLQAPRSCSAATSNDNVIQSNGQE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48563-1", "uniprot_id": "MON2_YEAST", "id": "P48563-1", "name": "Protein MON2", "aln": "------MAMNTGGFDSMQRQLEAELRSLSSESKRRNSTIRHASDKSIEILKRVHSFE------ELERHPDFALPFVLACQSRNAKMTTLAMQCLQGLSTVPSIPRSRLSEILDAFIEATHLAMEIQLKVLQVVPIFFKTYGKFIYGPLCKKLLLCCSNLLHVPNKAPVVVGTASATLQQLIDEIFDRLSIESVVDDKQYEVLISNSESIKVNVYRYDANKLFDNICSLNEISSNGAVSDEEMLLDIGDIPIDYGLEILESILKNSQKNLLECQDLQYLLRVKAIPLLLRCISSSRHFSTAVRSCR--------------CLKLL-----IRKEYLSILELELEVILSLLIHGISVESNLSGWQRVLSLELFKDLSQDPEIVNTLYMDYDNYPDKKHVFKYLLKECIVLLNS----------PEYITFLAPSKVVEKMDSP---------------------------LITTENSTVKTKFMHLLDKSNAPSINITYIISLILTICNHLCEGLNKSALESS----------------------PLEKKIEDKEREEGTGNDSTVVKVYSGLFSGLFELNKLFLYSTSLETSIFHLVVRAFQKLAHSAGVLSLKDKLRACMKLFSILITNNVTSSNQYSFNDTSKSAKNQHTRNIS---TSSVTTSPVESTKNPSRSIADSAQNKEMKR-----RLHPRNISSRQVSLLRALISLSISLGPIFDSESWRYTFLTWQWITYYIYGPSADFKESFYSEDIPPPPILTKSDVTSIESSLTKFFESTSSYSCSTFHLVLTRLILDSKNTLTLEQTNLNLNNDIGYHPLDAKDEIIPCIYNKAFFVNKIGELATYNCKKFLFGKNGKELWSLISTYMIKLISNREMDNDSLRLYTVRVFTDIIKKATNEVGNSDEQDNKVKQFGTLENLVIDSLMATINSIKQLDIGKQEIYNGTINVESDILFQLLLTLKEILNEFGELLMNSWTNIFNIINSPFEWTVEDTDFSVNEDIDDSSLFEGIVQKHKNMIQVSYDVFKLISDDFLQSLPMSVIKFVIDTLVNFVSQKRNLNISFSSISQFWLVGDYLRVRFNPETLNLSDEKRRSLSEKINNQKLIEIITSSSSHDWELYNGLWIYLLKNLINCTNDDRVEVKNGAVQTFFRIIDSHSVCFPP--WDLIFLEVIEPLLTKEWSTEELENET-----------------------DFINVTLQGLIKLYPEHFKDFKNNTTCAKEWSMLLDFLKRLLSSTSNNTKNAVILNYQTLLKEIITIED---------------------------------------------------------VPSDILKKCCEIFTDYNITYSDLSTNASSKTEY-----------------DCIYELITGFPPLYQLISKYDAMTDEFVEKVLLLFNSAIKYPLLPEFVQDKTKPSSMQKAILSGLDIFMTNDSKDTEILILLQLSTISILAFDTREKITKKLGPKLPKASLNRLPTFEAISYMSCSNLRNRIAKIDQFGISTLKAKHILRILKNLAEIIKRKSLITGSESDEIPIWVLASNCFCDLSNKIFKSLQEDAENPLKDNFCDLFINVIVVTLQRINPELDNLTEIDDLNEYSKYREILLENRIIDLFNERQLDTFIYAVWDCSFLYEFDELENALMQDCGTFSELSQKLSSFDFSCIFGSTTNPRFQTKYKCSLECLQDLVNFMLNTNEK--------------------LRKLTAPYLSARIALALRRYISDEYLIGRAPIPKLRKTELATLLNGLCVILRGVLDQNSTLGNKQIGVENLQTLSPLILRTIPVSHKMDGLQDKVLELSLGFTKLD-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ...: . :::::::** * *:: . ::.*.:..* : : : :. *:: .* ::: *: :.: :* * : : . * : : . :* ::*:**.* :::.* . *.* ::** ** . * .**.**::*:: :*:*: *. : . * :::: . .. *:.: ::. :***:**::*.: : : ::: **: :. .*::: :*.. :. .. .::** : :.: ::* * *::***::: :. :. . * *.:::* .: : . :: : .** . .::.: :: :. . . . : . *: ::.:*** :...* * :*: .: ..: :: .. :..*: :: :: : : . :::* . * .* * * : .. : . . : . :: . . : . .. : .:. . . :: :::. :*::: *: * :. **: .: * * :.: : .: . .. : .: . : * *.. :. * : :::: .*: * :: . : . . : . : * . : ** :: :::: :.:: . :* : ...:* ::: . :. : : *: :::..* . ..*: : * : :**: *: * .*. :: ::. ::.:. .:. :*:.::: ::*: *** :* : : :.. .* :.::****:::*. :* :.*:: .:. .: : : :: **: * :* : * * *::.* **:* * :*. : *. :. :*: ** . .: : :** *: ::: : :: : *.::*:.:: *...:.. *.: . * :: . . : . : : . : . : : *: **.::* * :. ..*. :: .*: *: .: : .::*: *. : . : . :. : :: . : . . .: :. .: : : :. ..::: . ..* : .: . .: : . : .* : .. :: . :*:. : :. : : :: :. :* : : ..* . : : :: : : .. * . * * ** . . : ::: . * * .*:*: .** *:.*:*: : :*: :*:.:..:: .: . . : : : . *: * .: ..* .: : ", "identical_positions": 170, "similar_positions": 553, "identity": "9.08%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2721", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62847-1", "uniprot_id": "ADDG_RAT", "id": "Q62847-1", "name": "Gamma-adducin", "aln": "MSSDTSQAVITTPPPPSMPHKERYFDRINESDPEYLRERNMSPDLRQDFNMMEQRKRVTQILQSPAFREDLECLIQEQMKKGHDPTGLLALQQIADYIMANSFTGFSSPPLSLGMVTPINDLPGADTSSYVKGEKLTRCKLASLYRLADLFGWAHLANTYISVRVSKEQDHIIIIPRGLSFSEATASALVKVNIIGEVVDQGSTNLKIDHSGFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLILGDVAYYDYQGSLDEEEERIELQKVLGPSCKVLVLRNHGVVALGETLEEAFHYIFNVQMACEIQVQAVAGAGGVDNLLILDLQKYKAFTHG-------------------------VAMTGGGGVNMGSHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLVR-EKPRHKSDVEIPATVTAFSFEDDSVPLSPLKYMAQ---RQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDPSKVSSGTPIKIEDPNQFVPLNTNPTEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMRFE--------------------------DDDQGPPAPPNPFSHLMEGELEEYTKTIERKQQGLDDAEQESLSDDAASVSQIQSQTQSPQSVPERLEENHELFSKSFTSVDVPVIVN---------------------------------------------------------GKDEMHDVEDELAQRVSRLTTSTTIENIEITIKSPDRTEEVLSPDGSPS-------------KSPSKKKKKFRTPSFLKKNKKKEKVEA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYB5-1", "uniprot_id": "ADDG_MOUSE", "id": "Q9QYB5-1", "name": "Gamma-adducin", "aln": "MSSDTSPAVVTTPPPPSMPHKERYFDRINESDPEYLRERNMSPDLRQDFNMMEQRKRVTQILQSPAFREDLECLIQEQMKKGHNPSGLLALQQIADYIVTSSFSGFSSPSLSLGMVTPINDLPGADTSSYVKGEKLTRCKLASLYRLADLFGWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASTLVKVNIIGEVVDQGSTDLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLILGDVAYYDYQGSLDEEEERIELQKVLGPSCKVLVLRNHGMVALGETLEEAFHYIFNVQMACEIQVQAVAGAGGVDNLLVLDLQKYKAFTHG-------------------------VAMSGGGGVNMASHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLVR-EKPRHKSDVEIPATVTAFSFEDDSAPLSPLKFMAQ---RQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSSGTPIKIEDPNQFVPLNTNPTEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQFD--------------------------DDDQGPPAPPNPFSHLLEGELEEYTKTIERKQQGLDDAEQGSLSDDAASVSQIQSQTQSPQSVPERLEENHELFSKSFTSMDAPVMIMN--------------------------------------------------------GKDEMHDVEDELAQRVSRLTTSTTIENIEITIKSPERTEEVLSPDGSPS-------------KSPSKKKKKFRTPSFLKKNKKKEKVEA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UEY8-1", "uniprot_id": "ADDG_HUMAN", "id": "Q9UEY8-1", "name": "Gamma-adducin", "aln": "MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPINDLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLRNHGVVALGETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYT-------------------------VAASGGGGVNMGSHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIR-EKPRHKSDVEIPATVTAFSFEDDTVPLSPLKYMAQ---RQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGGTPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQFE--------------------------DDDHGPPAPPNPFSHLTEGELEEYKRTIERKQQGLEDAEQELLSDDASSVSQIQSQTQSPQNVPEKLEENHELFSKSFISMEVPVMVVN--------------------------------------------------------GKDDMHDVEDELAKRVSRLSTSTTIENIEITIKSPEKIEEVLSPEGSPS-------------KSPSKKKKKFRTPSFLKKNKKKEKVEA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7V8-1", "uniprot_id": "A0ACD6B7V8_DANRE", "id": "A0ACD6B7V8-1", "name": "", "aln": "MSGEPRQEVVTTPPPPSVGKREGYFDRVNENDPEYLRARNMSPDLRQDFNMMEQKKRVTQILQSPAFKDELEGMIQEQMNKGNNPTGLLALRQIADFFMSSSVAGFSTSPLSLGMVTPINDMFSVESSTMVKGEKQTRCKLASLYRIVDLFSWAHFASCYITVRVSKEQDHILIIPRGLSFAEASASNLVKVNILGDVIDQGSTNLRIDAAGFSPHAAIYSIRPDVRCIVHISTPATAAVSSMKCGLLPISQEALILGDIAYYNYQGSLDEQEERVELQKALGPTAKVLVLRNHGIVALGETIEEAFHYIYGAQYACEIQVNAFSCAGGMENLIVLDLEKFKARTQG-------------------------VAQVG---VNMGSQQKWRLGELEFESLMRMLDNLGYRTGYTYRHPIVR-EKPRHKSEVEIPATVTAFMFDEDDAPRFPLKLLQQ---RQQREKTRWLNSPNCYMKVNVADGAS--EENRRTKTTWMKSDDGGNAS-GTPIRIEDPNQFVPLNTNPSEVLQKRNKIREQNRFDVMTAGPQSQKLAGIVVERPPGQSPVQPYMG---------------------NDEEETGPLPPNPFSELNE--KEEHQRRLR-----IDADEEQLTSDDASTLS----QSVSPQHTPAK-EENHTG------------VMLN--------------------------------------------------------GKDDHGD-EDELIKRVSQLTTS--LESMEISVRSGEKIEEALTPESSPS-------------KSPNKKKKKFRTPSFLKKNKKKEKVEA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02645-1", "uniprot_id": "HTS_DROME", "id": "Q02645-1", "name": "Protein hu-li tai shao", "aln": "------MTEVEQPPQNGIDPTAGEDDDNSKARP---------ADIEQDMREMERRKRVEAIMGSKLFREELERIVDSARDGG---AGASGILQQLSDIVGVPVSRVGSVFKSSNCMVPINDIRGVESMGYAKGEKILRCKLAATFRLLDLYGWTQGLGAQITARLKVDQEYFLVNPYGLLYHEITASALNKVDMQGQIVEQGTTNFGGNKSHFVLHSVVHAARPDIRCAIYIGCSPVVAISSLKTGLLPLTKDACVLGEITTHAYTGLFDE-EERNRLVRSLGPNSKVILLTNHGALCCGETIEEAFFAACHIVQACETQLKLLP--VGLDNLVLIPEESRKAIYEQSRRPPEDLEKKFAAVAAAEDGAATAEKDAAEAVPKVGSPPKWRVGGAEFEALMRMLDNAGYRTGYIYRHPLIKSDPPKPKNDVELPPAVSSLGYLLEEEELFRQGIWKKGDIRKGGDRSRWLNSPNVYQKVEVLETGT---PDPKKITKWVAE---GSPTHSTPVRIEDPLQFVPAGTNPREFKRVQQLIKDNRRADKISAGPQSHILEGVTWDEASRLKDATVSQAGDHVVMMGAASKGIIQRGFQHNATVYKAPYAKNPFDNVTDDELNEYKRTVERKKKSVHGEYTDTDFSESEAVLQAG-TKKYPQSEPETEHQVIEIQTQQAPVPRQAEVVLSDALVSQLAQKYAFLYSPGQYMYACMKMAPLMHKVYVIHKVEPVSKHNYPPVNDGNMSIHHNESGAGFMAQESSVISSTPVRNALASVSLPEERNHSILGLSSTPYRTISHFGFNCPLITSPTILLHPEHRSIWQRVAEQREKVVSFIDLTTLSLDNRKLLNVVTSTHPTQCQSQSQSFISEKHIQLEVTPPKRKQRVYSATISSGLDDSLDELDSLMSGLAINMPRSREQDSGLYRSYTFLPSNHALPKDTDANNRDQTDRERPEAEQEESFHCAGDSGIGDSTGRRPRLATTSNDSSIQEAEAYTQGKHVKLTLSSSPTPTATQSPATIEILINVSLRNAECVQTVQTHEQEFRAKLERVIDEEIHYISQQLAFKQRQAELHEQQTTSRAPIATPSFTTMHPPAPASSSSMVHRSNSAPELCHTYSYVAVGDLSTKQDQASPQLPAEGEPLNDILSSLEKELERLLNSVVTAHMLHNKAIIHECRARFSQLADGIVSS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** .: * .: * .*:.**:. **::*** *: * *:::** :::. . * :* .: * . :: ..: ..: * . :.****: ..:: .**** *****: :*: **:.*:: . *:.*:. :*::::: * ** : * :** * **:: *::::**:*:: : : * *:.::: ***::* ::* ...*:**:* *:**::::: :**::: : * * ::* *** .* : ***..**::* *** :. ***:****. *** *:: .. *::** :: :. ** . ::.* **::* ***.*** *** ****** ****::: : *: *.:**:*.:*::: : : : *: :::******* * **:* : . . :. .*: .. : .**::**** **** .*** *. . :: *:::.* * :*****: * *:. :... * . ***..: : :*: : :. :. .:: :: . ** * .: :: . .. . . : :. * :::: : : . :: .. * ..:* .**. : : . : : :::*** : ", "identical_positions": 184, "similar_positions": 233, "identity": "15.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2741", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UBY9-1", "uniprot_id": "HSPB7_HUMAN", "id": "Q9UBY9-1", "name": "Heat shock protein beta-7", "aln": "----------MSHRTSSTFRAERSFHSSSSSSSSSTSSSASRALPAQDPPMEKALSMFS---------DDFGSFMRPHSEPLAFPAR-------PGG----------------AGNIKTLGDAYEFAVDVRDFSPEDIIVTTSNNHIEVRAEKLAADGTVMNTFAHKCQLPEDVDPTSVTSALREDGSLTIRARRHPHTEHVQQTFRTEIKI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RPE6-1", "uniprot_id": "A0A8M1RPE6_DANRE", "id": "A0A8M1RPE6-1", "name": "", "aln": "MHCCGSLYEGCSSGERSVSISMASFQHSSSRVSTSTVRSFSGAERPRIHNLETDISAISSSGQDQTWADSFTDYQVYQGDRESFGGYDEDQKYIPGRNQVDWSLGDHMKTGSEVGVVRAVGENYFLSADVSGFEPHEVVVLAYNQCVVIHAEKSGSDVGVSGRFTHKSVLPADMDPLSVSSSLTSDQTLIVSIRRIPKTSSFDLL-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *. : **: *** *:** * * * .: :*. :* :* *.* .: :.: :* . ** .* ::::*: * ::.** .*.*.:::* : *: : ::*** .:* * . *:**. ** *:** **:*:* .* :* : ** *:*. .: ", "identical_positions": 53, "similar_positions": 53, "identity": "25.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2743", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LMV6-1", "uniprot_id": "DESP_RAT", "id": "F1LMV6-1", "name": "Desmoplakin", "aln": "MSCNGGSHPRINTLGRMTRAESGPDLR-YEMTYSGGGGGGGGGGGG---TSRMYYS--RRCTVNDQNSDGYCQTGTMSRHQNQNTIQELLQNCADCLMRAELIAQPELKFGEGIQLAWNRELDEYFTQANDQMEIIDGLIREMRQMGQPCDAYQKRLLQLQEQMRALYKAISAPRVRR----ASSK--GGYTCQSG---SGWDEFTKRLTGECLGWMRQQRAEMDLMAWGVDSGSVEQHINSHRSIHNAIGDYRWQLDKIKADLR---EKSAIYQLEEEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTN--IAQKQEAFSIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHLKENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYKRQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSKWYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWHYCMIDIEKIRAMTIAKLKTMRQEDYMKTIEDLELHYQDFIKNSQGSEMFGDDDKRRMQSQFTDAQKHYQTLVIQLPGHP-----------QHQTVTKTEITHVGTCQDVNHNKVIETNRENDKQ--------ETWLLMELQKIRRQMEHCEARMTLKNLLLTDQGSTHNITVKINELKSVQNDSQALAEVLNQLKD-MLANFRGS---EKYCYLQNEIFGLFQKLENINGVTDGYLNSLCSVRALLQAILQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQIHSQSSQQYPLYDLDLGKFTEKVTQLTDRWQKIDKQIDFRLWDLEKQIKQLRNYRDNYQSFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHNEISGKRDKSEEVHKIAELCANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDYYRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFKAKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKTVEDRFDQQKNDYDQLQKARQCEKESLGWQKLESEKAIKEKEYEIERLRVLLQEEGARKREYENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEVELKQVIQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEYQEEAKRRWEYENELSKVRNSYDEEIISLRNKFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEVKRLKNTLAQTTENLRRVEENVQQQKASGSEMSQRKQQLEIELRQVSQMRTEESMRYKQSLDDAAKTIQDKNKEIERLKQLVDKETNERKCLEDENSKLQRVQYDLQKANNSATEAMSKLKVQEQELTRLRIDYERVSQERTVKDQDITRIQSSLKDLQLQKQKAEEELSRLKRTASDESSKRKMLEEELEAMRRSLKEQAVKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHVREKQRTQEELRRLSLDVEALRRQLVQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADNDKNSTISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQESKSQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEETIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRETQSQLETERCRLQKEIDKLRQRPYGSHRETQTEYEWTVDSSKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVASEIQPFLRGAGAIAGASASPKEKYSLVEAKRKKFITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAIARDLIDFDDRQQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQLASGGVVDPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQKNFVDPITKKKVSYMQLRERCRIEPHTGLLLLSVQKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKDFLQGSSCIAGIYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTS-QKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRKFFDQYRSGSLSLTQFADMISLKNGVGTSSGLSGSVNDDVFSSSRHESVSKISTISSVRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGLIDQDMATRLKPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRSGSRSGSRSGSRRGSFDATGNSSYSYSYSFSSSSIG-Y", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q557-1", "uniprot_id": "DESP_MOUSE", "id": "E9Q557-1", "name": "Desmoplakin", "aln": "MSCNGGSHPRINTLGRMTRAESGPDLR-YEMTYSGGGGGGGGGGGGG--TSRTFYSHSRRCTVNDQNSDGYCQTGTMSRHQNQNTIQEMLQNCSDCLMRAELIAQPELKFGEGMQLAWNRELDEYFTQANDQMEIIDGLIREMRQMGQPCDAYQKRLLQLQEQMRALYKAISVPRVRR----ASSKGAGGYTCQSG---SGWDEFTKRLTGECLGWMRQQREEMDLMAWGVDAGSVEQHINSHRSIHNTIGDYRWQLDKIKADLR---EKSAIYQLEEEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTN--IAQKQEAFSIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHLKENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKIIEYKRQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSKWYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWHYCMIDIEKIRAMTIAKLKTMRQEDYMKTIEDLELHYQDFIKNSQGSEMFGDDDKRRMQSQFTDAQKHYQTLVIQLPGHP-----------QHQTVTKTEITHLGTCQDVNHNKVIETNRENDKQ--------ETWLLMELQKIRRQMEHCEARMTLKNLLLAEQGSTHHITVKINELKSVQNDSQALAEVLNQLKD-MLANFRGS---EKYCYLQNEIFGLFQKLENINGVSDGYLNSLCSVRALLQAILQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQIHSQSSQQYPLYDLDLGKFTEKVTQLTDRWQKIDKQIDFRLWDLEKQIKQLRNYRDNYQSFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVHKIAELCANSIKDYELQLASYTSGLETLLNIPIKRTMVQSPSGVILQEAADIHARYIELLTRSGDYYRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFKAKLVSLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKTVEDRFDQQKNDYDQLQKARQCEKENLSWQKLESEKAIKEKEYEIERLRVLLQEEGARKREYENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQMDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSETMQKKQRLEIELKQVIQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEYQEEAKRRWEYENELSKVRNSYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLCEEVKRLKNTLAQTTENLRRVEENAQQQKATGSEMSQRKQQLEIELRQVTQMRTEESMRYKQSLDDAAKTIQDKNKEIERLKQLVDKETNERKCLEDENSKLQRVQYDLQKANNSATEAMSKLKVQEQELTRLRIDYERVSQERTVKDQDITRIQSSLKDLQLQKQKAEEELSRLKRTASDESSKRKMLEEELEAMRRSLKEQAVKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHVREKQRTQEELRRLSLDVEALRRQLVQEQENVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNSTISELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQESKSQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKATLEAESRVKQRLECEKQQIQNDLNQWKTQYSRKEETIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSSRETQSQLESERCRLQKEIEKLRQRPYGSHRETQTEYEWTVDSSKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVASEIQPFLRGAGAIAGASASPKEKYSLVEAKRKKFITPESTVMLLEAQAATGGIIDPHRNEKLTVDNAVARDLIDFDDRQQIYTAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQLASGGVVDPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQKNFVDPITKKKVSYMQLRERCRIEPHTGLLLLSVQKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKDFLQGSSCIAGIYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDMAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTS-QKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYDTFKELCEQECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRKFFDQYRSGSLSLTQFADMISLKNGVGNSSGLGGSVNDDVFSSSRHDSVSKISTISSVRNLTIRSSSLSDPLEESSPIAAIFDTENLEKISIAEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVNQGLIDQDMATRLKPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQFLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDISSYAKILTCPKTKLKISYKDAMNRSMVEDITGLRLLEAASVSSKGLPSPYNMS-APGSRSGSRSGSRSGSRSGSRSGSRRGSFDATGNSSYSYSYSFSSSSIGGY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15924-1", "uniprot_id": "DESP_HUMAN", "id": "P15924-1", "name": "Desmoplakin", "aln": "MSCNGGSHPRINTLGRMIRAESGPDLR-YEVTSGGGG------------TSRMYYS--RRGVITDQNSDGYCQTGTMSRHQNQNTIQELLQNCSDCLMRAELIVQPELKYGDGIQLTRSRELDECFAQANDQMEILDSLIREMRQMGQPCDAYQKRLLQLQEQMRALYKAISVPRVRR----ASSKGGGGYTCQSG---SGWDEFTKHVTSECLGWMRQQRAEMDMVAWGVDLASVEQHINSHRGIHNSIGDYRWQLDKIKADLR---EKSAIYQLEEEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTN--IAQKQEAFSIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHLKENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYKRQVQNLVNKSKKIVQLKPRNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSKWYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWHYCMIDIEKIRAMTIAKLKTMRQEDYMKTIADLELHYQEFIRNSQGSEMFGDDDKRKIQSQFTDAQKHYQTLVIQLPGYP-----------QHQTVTTTEITHHGTCQDVNHNKVIETNRENDKQ--------ETWMLMELQKIRRQIEHCEGRMTLKNLPLADQGSSHHITVKINELKSVQNDSQAIAEVLNQLKD-MLANFRGS---EKYCYLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAILQTEDMLKVYEARLTEEETVCLDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQIHSQTSQQYPLYDLDLGKFGEKVTQLTDRWQRIDKQIDFRLWDLEKQIKQLRNYRDNYQAFCKWLYDAKRRQDSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVQKIAELCANSIKDYELQLASYTSGLETLLNIPIKRTMIQSPSGVILQEAADVHARYIELLTRSGDYYRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFKAKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFDQQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEEVASEIQPFLRGAGSIAGASASPKEKYSLVEAKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDRQQIYAAEKAITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVVDPVNSVFLPKDVALARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSVQKRSMSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKDFLQGSSCIAGIYNETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGLCLLPLKEKKKQVQTS-QKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRKFFDQYRSGSLSLTQFADMISLKNGVGTSSSMGSGVSDDVFSSSRHESVSKISTISSVRNLTIRSSSFSDTLEESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQDAVSQGVIDQDMATRLKPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRSGSRSGSRSGSRRGSFDATGNSSYSYSYSFSSSSIGH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BID5-1", "uniprot_id": "DESPA_DANRE", "id": "A0A8M2BID5-1", "name": "Desmoplakin-A", "aln": "MSLSG-SQTRLHQISRRSSSRPDLTAVGYSLPRNDGAQFFTSGNGYQSDYNDGYMQTYTQTFSKNSQGGGAGGAQSMSSMAVQKRAQMLYSDCMGFLQRAQGLLE---------TMGPASEVDKNMMAAQDAMDQLRKCAVDMRNAGLPNDMILRSLEDCHSFYADIRNSITGTTIRRTGGTVSGTIGGTISGTIGGTVGGWDDPSKSFQ-DALSWINQKKRLIETSGFGENSEAISQQILNHNKFHSSIQRS-QEVDRARDDLMQSREKAGLHALDQEWDSLQKMSHARMDHLRDLQSIIEEISRAIMWVNDREEEELVFDWGDKNIDNYIPQKQESYSKLMSDLEEKEKELNKLKAKVDMLLKNQHPASDKIEAYMDTLQTQWSWLLQITKCIHVHLKENAAYSQFFKEANETYSRLQKDHENIRKKFGCDKTTPLENLNDMLKNLEKEKEKVIENKRQVQTLVSKSKNIVCLKPRNPEEKSSSPVIVQALCDFKQDQKGIMKGNEGILKDNSQRSKWHVTGPGGLEMLIPSVCLIIPPPNPLSISLANKNEQYYEAIMSIWSQLYINIKSLISWQYCLRDIQHINSLTLSMLTQMRPEEYRQTIKNLEIHYQEFLRNSLGSEMFGDDDKRKMELQYAGAQSHYDQLVIQLPNYRENGVIREVVMVETDSKLKSEVSSGKTATGVSSGKTATGVSSGKTSSSVSVSGLNVSLLSDLSALRRRLETAESGLTKHLHVPLKENSVQECSQRLAQLQAVHRDLDSIRDEYLHLREKIMRELEGSSDPEQSRYLRAELDLINQKLGSLQGFSSAYIQRLGALQALLQHLLQAEDIIKVHEARLTEKETSSLDLNEVEKYCMTLKTMKAELEQKKGVLKAMETELSKAVHWNSQIDQSFHQCDVDLSRYTELVGQMTDRWRRIVTQIDSRTWDLEKQEKQLNHYQQTSSTINRWIQDTRQRQDTLQITKFNSVDNLMDHLNQQKALYSEIKGKKEKVDAVVKDSDTCAASIKDYELQLASYSAGLETLLNIPIKKTMLQSPATVLREEATDLQSRYIELLTRSSDYYKFLGEMLKNMEELKMRNTKIELLEEELRRLKDNLKDQNQKNKSLEDSLTRFRLELTQSKEQLISMEEVKRTQARQCNTAQESLDSTQNQLKSLQDEMSRLTFLIEEEKRKRRLAEERYTNQQEEYELAMRKRQKELEELTLSKSQFERAIKEKEREIERLKLQLQDEASRRSAAELETSKT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SMMIQRSDSNYKDIVQERDSLLIKLKLLQQDKDKQQRYEEELRRIKLTLESETKQKQRLQDEIDKITKDFKYWKSQYELKEGQIRQSEMDRDRVERDRASLQSEIQRLTAELRSVEERYRGRLQSSDKE-ISELMRKKESLEIELRRLQQRPAATWKQTQTD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EISKP-------------------------------------VVEQKLTVQGLRGEVSLTELVESDLLDQTDLDKINRGQLTSKDIEHKLKSYLGGSDCIAGIYDEAKDRVMPFYQAMKDGLLRRGTTLELLEAQAASGFIIDPVNNVCMTVEEAWKRGLVGKEFKDKLLSAEKAVTGYKDPATGKIISLFQAIEKEIIEKGHGIRLLEAQIASGGIIDPKGSHRIDVEVAYRKGYFDREMNEILSYEGDDTKGFFDPNTHENLTYLELKKRCIKDPKTGLMLLPLNDKQKPKQTTTQKNTLRKRRVVIVDPDTGKEMTVREAYHRELIDYDTFLELSEQECEWEEITIETSDGNKRLLIVDRKTGIQYDIQESLQRGIINKQTLEKYRAGTMTLTEFAALITSKSNSSELAIFSSSP-EDVATCSSPTQPSSPTVRKRFASVSITLSPPSDIFDDQSPVGAIFDTETLEKITIPEAQRRGIVDNITAQRLLEAQVCSGGIINPATGQRLSLKDAVQQSLIDEDMSVKLKPAQKAYDGFEDVKTKRKLSAAEAMKEKWLPYEAGQRFLEFQYLTGGLIEPGTGRRVSIEEAIRKGWLDGKGAQKLQDTRNYIKNLTCPKTKLKISYKEAMDNCMVEENNGMKMLQATSMSTKGISSPYNVSSGPSSRSGSRAGSRTGSRSGSRRGS-------VDYSSSSVSYTFFSSAS---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .* *:.*:: :.* :... *.:. ..*. . : . : .:.:..* : :** *: * : .:* . * **: : : : *:*: : *:* *: : :**: * * * : * : :. : ::*: . :** .*.. * : * .***: :* . :.*.*:.*:: :: .:* : ::.*:* .*. :*.:* ::*: : ** **:.:: *::*::.* * *. ******:**.**: ** ***:** *****::**.*** : *.****::* **:** ********* : * *: **********************:*******.********* ***:**:.* : *: ::.****: ***. **::* : :*:****:**::* *****.**.***:** ******: :*..*:*::****:***** : **:* *****.:****:******::**:*** *********::.*: * *******:::*.*****:***:**:**: **::*.::*:: *. ** *:* :** :**:***:*::** ***********::: *::.**.**: ******.: : :: .:*:: *. .*. .*. ..... :. :* :*. :**::* .*. :* : .:.* :. : :: :*::*:.* ::: : :*:: :: ::.** *: **: *: : *** .::*.:..*:: * :::**** :**:**::**:******:** .***::** * **.:* :*: **.:* :*:***.** : :** .*.: *:**.:: * * *:****::* .*** * ****** ***.:*::. .:: :*: *:::***:*: **.. :.:* .**:** *:.**.**::* : * * :: ** ************::***********:**:***: *: :**:*:::*********.***:**.****.:*:**::*****:****** :* .:: :*** *::.* ::: * :* * :* *:**:** : ::*::.**. .*:*.*:::::***: **:***:*: .*:*: :*:::*: : ** * *.* .* : *:****** *****:: **:*.:*: * * :*. * **.*..: .::****:***:*:*:*:*** : ** *:**.* * ***:*:: ****: * ::* :*:: **:**. ** **: * :*:: **:: **:***:** **:: :*** * :*:.* :* *:* :: : *: :*:*** .: ::***: .:..* * ::.::.**:* *::****:*.:* : ::::: **:: .:: .::*.:* **.******:*:..: : :*:*** **:* **:*********:***:***.*: :.****:****** ***:******:*****:** **:*******::**:***************:******* ***: *::**::***:.*:.**** .***********.******:**:***** :*** ****::*:* **: ***************:*.***:*:***:: ****:** **.*********** ***..*:::****** *****:::::*::::: :::**:*:::**:** :*: *.. . : :... :** :.* . *. :. . . .::* *. ** :::.**:.******.****:*.*. .*****.**.*******.*:****:*:***:***:***.*.:**:**:.:*******: ***.** *:*:*****:*****************:*****::* . *:* *******::**:.**:*** .* * *************:*::..***: .*:::*:*:*:*:**:.****:* .*.******:***:******* ** .. ** * **:* **: ", "identical_positions": 1002, "similar_positions": 645, "identity": "34.28%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2746", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y016-1", "uniprot_id": "A0A8I5Y016_RAT", "id": "A0A8I5Y016-1", "name": "", "aln": "-MQRMIQQFAAEYTSKNSSTQDPSQPNSTKNQSLPKASPVTTSPTAATPQNPVLSKLLMADQDSPLDLTVRKSQSE-PSEQDGVLDLSTKKSPCASSTSLSHSPGCSSTQGNGEDSAEAPVADSNHPSKSPLEKFMVKLCTHHQKQFIRVLSDLYTESQPGSEDLQPLGPSVMDVSARDSDCAGLGSRDDEKDDACLDGGSPASVKLFLDSSGSPSSLNVTEETMKDPPPETDSVDGRENALSTVQKDSSGPPDAQQNPTGSADSPTVGCLSTLDSSSFNSPHSSKSLEGQTTGQEQDTDMKPREDAEDSAPASVQSLAAVELVAENTEEGGSCIVSQRNSFKALSEETWDSGFMGNSSSAADKENALQCGSRTSSPQDLETDEQDARPKQENHLHSVGRNKAGFQPYPRDKGHFDHSKGGWLAPSPTPAVHRASNGHSQTKMISASIKTARKSKRASGLRINDYDNQCDVVYISQPITECHFENQRSILSSRKTARKSTRGYFFNGDCCELPTVRTLARNLCSQEKGSCSPLTSEAVVTPKQTLTGPTSKHTVGVQLPTVGVQLPPGGVQLPTGGAQLPTVDAQLPTGGVQLPTADVQLPTVGIQLATADEQLPTVGAQLPTADEQLPTVGAQLATADEQLPTVGAQLPTADEQLPTVGAQLPTADEQLPTVGAQLPTADEQLPTVGAQLATADEQLP-TVGAQLPAADEQLPSVGAQLPTADEQLPSVGAQLPTADVQLPSVNAQLPTADVQLPSVNAQLPTVDVQLPSVNAQFPTVDVQLPSVNAQFPTADVQLPSVNAQLPTVDVQLPSVNAQLPTVDVQLPSVDVQIPTVDMQLPIAGEQLLKEDTRDDPRKERTSLEEGDKDTSSAKEHQEPEVCLTKNERDPSVSPRPGETTPSSPACLLPAALTNEDPSEMPEGSTVVSSPTASVLSFHEQDQPPAASLLGPEEMQAQECHLVLTGGSIPLTSGEGSEDLPWRPQFSPETAVREGRSPCSADKSPAMALDPPLSLELSEHDQSSSTEAEARDTPGETLLLDGSLPLLESSIVTDEKNPSQTEGGEVASGTGHLEAHDEDIKYSAENDPSEPNSGSPEENVDKKKKAKKLPEASDRCLRSQLVDSSSADRYPGSQGLDSNAACSEVNVSKNHAVKHSKREGDCGGVTSEGSVIDSNHTDSLEDTENPGVSEHSSDEETKQEAEGLGVITRQTVKNLLAKEVKREEGGTSPSSDPATVSQPSPQDNLGTRVWSKIDEKDAHVPSDSIPCKRDPEQVKENPGHIVIQDTEAAVREVDAEDTHHEDGAGRAPCSSAAISASQSGDAAGPPKLVRRPKRLPSSTYNLRPAHCVGALDTAKMTSEKQVTQVNPAPKESGASPSAESLDEEDSDTVAEEQPKFVGWCAEEENQELIASFNAQYLRVQKGWIQLEKETQPTSRARSKSDKLKEIWKSKKRSRKCRGSLEVQKFSPVQMLFMTNFKLSNICKWFLETTETRSLVIVKKLNTRLPGDIPLVKHPLQKYP-PSTMYPSSLQAERLKKHLKKFPGAIPARNNWKTQKLWAKLREN------PEQVEPDAGSDISLGPNSEDSVEEVRESR-HSHPPTNLPTPASTRILRKYSNIRGKLRAQRLDSSVGGASEIKQGRKSVCINPLMSPKLALQVGADGFPVNPKRAERSKGRRGKQMPETLLKVEGQNKRKRAEGSGTQDGKDKGPATKASRVLSAAKKLAAKDRVNQLSKKMTLKENKVRVCRKGPGKSCPASRKEKENANRRPGHPTAASAALAKPSKQRGAREASSKPPKARRRNRKLSSGRGRARPLAKSPENRTAPRKRKLKAKLDSSQGKRRRLEAK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8N7UUM9-1", "uniprot_id": "A0A8N7UUM9_DANRE", "id": "A0A8N7UUM9-1", "name": "", "aln": "MANLATKRLCTNERFPVRQDSDCWRSKLIRSVGLDRISDLLLRTQILDDLRLLKDCKPASVSHSSFDEKCLFCCLRREKVKEHITALNKQIVESGGKPLLGKDPSNISRLEWQSDEFLSAVLHRNEYTPRIPDPHIPVVACGVMQQMLSKLTTYYTSRNSCSQDSLQTNGKKDQSLVKTSRVS----------SSAAVGALSAQNKFIMVDQDAPLDLSVKKIKVEDIQQD-----------------------------GVLDLSTKKNLSKDHLCLKNSPVHVSPAARLVKRDSIDLSLAQVG--------DLQSASTLEQFMSKLCLHHQHQIVDALGFLQSEVKTVSNHFQTPISTLPEKQ-----ATTSSSIVSSESRSEVQRPERTCSVDAALSIKT--------------------QSVARSQKTTSEDLNADVSSIATSEKTVDICKKEDFSSSSSCGTVVELENASSPVTKTTTDHQEIKKSLVSSLQQVKHG-------------DSVKKCLCSAERCTCTAASDQEDLLSKHTDMSSVAQNEDAVVNPSTVHKASNVVLSVSPRTARKSRKGSCLRP---RNGSLSCIISDPDSHCDLVYIKKSIIECQPQSRNRLHPRLNARKSTRGHKYVEEYLELKTVRTLARKP---IHDSVGNCPVLLADLQTSVTPRQTLSGSVPLVNAPFTGDCMKNIIQKLSSEQIAEEEMPGDVVKVTGISLMVETSHTDKTETNSQISHEPSCKESEASMQIDVSLETVSCTPNAVEQEENMDVEEAKESTETTELAVETEQCDPPLVPIEEEQCDPPVVPIKEIQCNPSVVPIEKEVDCG--------TESKPECEGQSLEPSLSPASSNMDPESSTIEISDEQNNERESTSPTDAETDTADVQEPSEASEVNANTEEDRNAQEQTLGDVEPNLQMLPEKKEEDLSGSKIAEVSTVQALAN-------CKKDTDSIPPKVLSTKHTVSSDRCLRSRVSKASVDVVKDSVKHGASEP-VDHANDANTKTQSAETDVCTG--------------EEHNSEPVEIPIEKPNHPVIDNAVKTTPKSKGGKAKQQSPKVEMNEP------PSVLPPEVLPETISTASNTTESEKQHKMNSQASENLTLRSKSSPIELPVSGDCSPNKKSPHSSENMLLRSRSNTEKICGSKSNSLTDGHSETQGQTPLRENSST------SDQGSIGDLCTPSESATRMPLRSRTISTNKQTVTRESPVKCSIKSEPASSPSSKKIEANGHMPLRSSAGVTAEQPCNDKSALESPGRMSLRRGNASNTEKPCGSTTPPTANKR---PSRIHKVSASSSGDAEEIPSSSKLEIQNKKHTESQIKGSDEFFHVPSLPRSEPIVCNPSKFLEALRGEEHQQLISNLNAKFDKMQKGWVQMDKEGQPAPKHKNKADRLKEIWKSKRRVRKSR-PLEQQKFSPVQMLFMKPFDLTSICRWFLQSTETKSLVIVKKVNTRLPSETQLCFHSSSAGAGSANGIFPSLQAERLKKHLKKFAIASPVKSNPKNQRLISKALGQGISLMSKEKPKPTTATRICTKAQSLAGVTPVQVPESISATAGSAKNPASARILRKYSNMREKLQVQQNKKCKEKALKSAGLKATIIPKKDDKEKLQTQKGPKSVVVKKISSLSKTAKANSVLKERALKSEDGSSTKRLQG-----------------LKRITQAIGAHASANKLSKKLVRTDKAQRVKS----IKVDSKKSALQKIPPEPQTLDVDSKSSEDQVLTRSQRKMEGAPSQTASPKSTMKRG----------LEPLVTPTKRTRTSKP-------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::.:: . .* :.: :. .* : * : . . : . : ..*.:* . . . . :: : *..: ..... *.:.*. * .*. :.* . *. : : .: :. :*:: *: **. :. *:* . . : .: * : .:. *. .*. *::: ...:* .*.*.: .::* : * * .* **. . . *** .. .. :. * .: .:** :::* . .: . : : .* . :* .. * *: .:*: .: :** . *: .: **:: :.:. *: . . . :.: :::.. *::* **. .*: . .. .. :: *.*:*: ::*. * .: :: .:* :: : *** *: :*:. :.: : .*:* ...::: .* *:. : . :.:.. *: . .: * . : : . :. . : . : . : .* : :. * :.*: :* ..: :* *. . : : : *.: *:* *: *:...:. .: :. :: .. . ::* ::..:. : *:..: ...*:*:. * : *.:: * ..: : :: :*: .* .:*. . * . * : . :.: *.* :: . : .: .:: :: . *...*. * *** . . :** : :.. : ::.::.: *. * :: ..:. *: :: :.. : .: .: .:: : .* *.: :.. : : . . :.::.:* : : .*. : . ..*:.. .:. .:. ** . :.:*::: ..** : * : ::* *:. . : . *: :* :.:.. .:.:. **: :::: *.. : .: :.::* . .* .. *..::.: .: : . .***. ... :. * .:**: *: .* : :.*::* : .:: . .: . * :.. ::. * . .:.*. : *. .: . .* *.. ..: * **: ::.: ... * .:*. :..** . . * ::. .: .* ..: ** ::: .: . .* : .. :. : .: :. .: .*:. . . *:.:. : .**: **:*:**:.:**:: ::****:*::** **:.: :.*:*:********:* **.* .** ***********. *.*:.**:***::***:*******:*****.: * *. . . .:. .**************. * *.:.* *.*:* :* : *: :* :.: *. .:* .* *: .. * .. . .***:********:* **:.*: ... * : : :: : . ** * *.... *: : ...: .. : * ** *. .. ** :* : :: :.*: .*:****:. .:: ** . :.:. :: .* . * : . *. *: .. *.:: : .:. * * .:* **. .:* ", "identical_positions": 302, "similar_positions": 679, "identity": "16.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2748", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55884-1", "uniprot_id": "EIF3B_HUMAN", "id": "P55884-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAA--EAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYPEEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGDRTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALWGGEKFKQIQRFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFHCESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQGVVTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHGEAPRISVSFYHVKNNGKIELIKMFDKQQANTIFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRGGVDTDELDSNVDDWEEETIEFFVTEEIIPLGNQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JZQ9-1", "uniprot_id": "EIF3B_MOUSE", "id": "Q8JZQ9-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MQDAENVAVPEAAEERAEPARQQPASESPPTD---EAAGSGGSEVGQTEDAEEDA---EAGPEPEVRAKPAAQSEEETATSPAASPTPQSAERSP--SQEPSAPGKAEAVGEQARGHPS-----AGAEEEGGSDGSAAEAEPRALENGEADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKIINDYYPEEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGDRTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALWGGDKFKQIQRFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFHCESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQGVVTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHGEAPRISVSFYHVKSNGKIELIKMFDKQQANTIFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQDQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRQYRKMAQELYMKQKNERLELRGGVDTDELDSNVDDWEEETIEFFVTEEVIPLGSQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "X1WET9-1", "uniprot_id": "X1WET9_DANRE", "id": "X1WET9-1", "name": "Eukaryotic translation initiation factor 3 subunit B", "aln": "MRDTENMEA--------------------------------------------------------------------------------------------------------------------------------------EMEYDDEEEPSFSDPEDFDDDISDQELLGDVLRDKPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNEFYPDADGKTKGYIFLEYSAPSHAHEAVKNADGYKLDKQHTFRVNLFTDFDKYMSICDEWEAPEKQPFKDFGNLRHWMEDPDCRDQYSVIYDSGERTGIFANDVKEPIEVEERARWTETYVRWSPKGTYLATFHQRGIALWGGEKFKQIQRFSHQGVQLIDFSPCERYVVTFSPLMDTKDDPQAIIIWDVLTGQKKRGFHCESSAHWPIFKWSPDGKFFARMTQDMLSIYETPSMGLLEKKSLKINGIKDFSWSPGDNIIAFWVPEDKDIPARVTLMQFPSRNEMRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQGVVTNFEIFRMREKQVPVDVVEMKDSIIAFAWEPNGSKFAVLHGESPRINSSFYHVKSNGKIDLIKMFDKQQANSIFWSPQGQFLVLAGLRSMNGALAFVDTSDCTMMNIAEHYMASDVEWDPTGRFVVTSVSWWSHKVDNAFWLWTFQGRLLQKNNKERFCQLLWRPRPPSLLTQEQIKLIKKDLKKYSKIFEQKDRLSQSKASKELVDKRRTMMEEYRKHRKRAMDMYQEQRPLRLELRGGVDTDELDSNVDDWEEETIEFFINEEIIPIGDL-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*:**: . :* .: :********** **:*::*******:*:***************************************** *::**: ************::*:** :****************************:*.***: ********:****:*:*:.:********::**:**.** ****:*:.:*********************************:************************:*********:**********:***:******************* ********* * ************:******.**********.*********************:*:*:*:**********************************************************::*******************:***. ******.****:***********:*********:*********************:*******************:***************:***************:************:**:*:*** ****************************::******::*::** * ::* :*: ****************************:.**:**:*. ", "identical_positions": 581, "similar_positions": 79, "identity": "71.2%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-275", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q794E4-1", "uniprot_id": "HNRPF_RAT", "id": "Q794E4-1", "name": "Heterogeneous nuclear ribonucleoprotein F", "aln": "--------------------------------------MMLGPEGGEGYVVKLRGLPWSCSIEDVQNFLSDCTIHDGVAGVHFIYTRE-GRQSGEAFVELESEDDVKLALKKDRESMGHRYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPN--GITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRP--GTARRYIGIVKQ-------------------------------------------------AGLDRMRSGAYSAGYGGYEEYSGLSDGYG-----------------------------FTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTG-----------------------------------------------------------------------------HCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANMQHRYIELFLN--------------------STTGASNGAYSSQVMQGMGVSAAQATYSGLESQSVSGCYGAGYSGQNSMGGYD-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2X1-1", "uniprot_id": "HNRPF_MOUSE", "id": "Q9Z2X1-1", "name": "Heterogeneous nuclear ribonucleoprotein F", "aln": "--------------------------------------MMLGPEGGEGYVVKLRGLPWSCSIEDVQNFLSDCTIHDGVAGVHFIYTRE-GRQSGEAFVELESEDDVKLALKKDRESMGHRYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPN--GITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRP--GTARRYIGIVKQ-------------------------------------------------AGLDRMRSGAYSAGYGGYEEYSGLSDGYG-----------------------------FTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTG-----------------------------------------------------------------------------HCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANMQHRYIELFLN--------------------STTGASNGAYSSQVMQGMGVSAAQATYSGLESQSVSGCYGAGYSGQNSMGGYD-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52597-1", "uniprot_id": "HNRPF_HUMAN", "id": "P52597-1", "name": "Heterogeneous nuclear ribonucleoprotein F", "aln": "--------------------------------------MMLGPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTRE-GRQSGEAFVELGSEDDVKMALKKDRESMGHRYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPN--GITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRP--GTARRYIGIVKQ-------------------------------------------------AGLERMRPGAYSTGYGGYEEYSGLSDGYG-----------------------------FTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTG-----------------------------------------------------------------------------HCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANMQHRYIELFLN--------------------STTGASNGAYSSQVMQGMGVSAAQATYSGLESQSVSGCYGAGYSGQNSMGGYD-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VHV7-1", "uniprot_id": "HNRH1_RAT", "id": "Q8VHV7-1", "name": "Heterogeneous nuclear ribonucleoprotein H", "aln": "--------------------------------------MMLGAEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTRE-GRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSEEEIVQFFSGLEIVPN--GITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRP--GAGRGYNSIGRG-------------------------------------------------AGFERMRRGAYGGGYGGYDDYNGYNDGYG-----------------------------FGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTG-----------------------------------------------------------------------------HCVHMRGLPYRATENDIYNFFSPLNPVRVHIETGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMGGMGLSN-QSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQE---NSSDFQSNIA-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35737-1", "uniprot_id": "HNRH1_MOUSE", "id": "O35737-1", "name": "Heterogeneous nuclear ribonucleoprotein H", "aln": "--------------------------------------MMLGAEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTRE-GRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPN--GITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRP--GAGRGYNSIGRG-------------------------------------------------AGFERMRRGAYGGGYGGYDDYNGYNDGYG-----------------------------FGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTG-----------------------------------------------------------------------------HCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMGGMGLSN-QSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQE---NSSDFQSNIA-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31943-1", "uniprot_id": "HNRH1_HUMAN", "id": "P31943-1", "name": "Heterogeneous nuclear ribonucleoprotein H", "aln": "--------------------------------------MMLGTEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTRE-GRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPN--GITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRP--GAGRGYNSIGRG-------------------------------------------------AGFERMRRGAYGGGYGGYDDYNGYNDGYG-----------------------------FGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTG-----------------------------------------------------------------------------HCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMGGMGLSN-QSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQE---NSSDFQSNIA-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6AY09-1", "uniprot_id": "HNRH2_RAT", "id": "Q6AY09-1", "name": "Heterogeneous nuclear ribonucleoprotein H2", "aln": "--------------------------------------MMLSTEGREGFVVKVRGLPWSCSAEEVMRFFSDCKIQNGTSGVRFIYTRE-GRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNSVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPN--GMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMTMQRPGPYDRP--GAGRGYNSIGRG-------------------------------------------------AGFERMRRGAYGGGYGGYDDYGGYNDGYG-----------------------------FGSDRFGRDLNYCFSGMSDHRYGDGGSSFQSTTG-----------------------------------------------------------------------------HCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKDKANMQHRYVELFLNSTAGTSGGAYDHSYVELFLNSTAGASGGAYGSQMMGGMGLSN-QSSYGGPASQQLSAGYGGGYGGQSSMSGYDQVLQE---NSSDYQSNLA-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70333-1", "uniprot_id": "HNRH2_MOUSE", "id": "P70333-1", "name": "Heterogeneous nuclear ribonucleoprotein H2", "aln": "--------------------------------------MMLSTEGREGFVVKVRGLPWSCSAEEVMRFFSDCKIQNGTSGVRFIYTRE-GRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNSVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPN--GMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMTMQRPGPYDRP--GAGRGYNSIGRG-------------------------------------------------AGFERMRRGAYGGGYGGYDDYGGYNDGYG-----------------------------FGSDRFGRDLNYCFSGMSDHRYGDGGSSFQSTTG-----------------------------------------------------------------------------HCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKDKANMQHRYVELFLNSTAGTSGGAYDHSYVELFLNSTAGASGGAYGSQMMGGMGLSN-QSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQE---NSSDYQSNLA-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55795-1", "uniprot_id": "HNRH2_HUMAN", "id": "P55795-1", "name": "Heterogeneous nuclear ribonucleoprotein H2", "aln": "--------------------------------------MMLSTEGREGFVVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTRE-GRPSGEAFVELESEEEVKLALKKDRETMGHRYVEVFKSNSVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPN--GMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRP--GAGRGYNSIGRG-------------------------------------------------AGFERMRRGAYGGGYGGYDDYGGYNDGYG-----------------------------FGSDRFGRDLNYCFSGMSDHRYGDGGSSFQSTTG-----------------------------------------------------------------------------HCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKDKANMQHRYVELFLNSTAGTSGGAYDHSYVELFLNSTAGASGGAYGSQMMGGMGLSN-QSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQE---NSSDYQSNLA-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QFJ8-1", "uniprot_id": "F1QFJ8_DANRE", "id": "F1QFJ8-1", "name": "", "aln": "------------------------------------------MADDEGFVVRVRGLPWSCSAEEVSRFFSGCKISSNGSAIHFTYTRE-GRPSGEAFVELESEDDLKIAVKKDRESMGHRYVEVFKSNNVEMDWVLKHTGPNCPETEGDGLVRLRGLPFGCSKEEIVQFFSGLEIVPN--GITLPVDFQGRSTGEAFVQFASQDIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYEPPRKGMGMQRPGPYDRPS-GGGRGYNGMSRG-------------------------------------------------GSFDRMRR----GGYGG--------------------------------------------------------GVSDGRYGDGG-NFQSTTG-----------------------------------------------------------------------------HCVHMRGLPYRATEPDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLN--------------------STAGGSNGGYGGQMMGGMGNQS---SYG-HGGQQMGGGYTGGYSSQSSMGGYNDYNSQGGMSNSYYGGSRGSVGMNGMGGGWGM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGH5-1", "uniprot_id": "Q9VGH5_DROME", "id": "Q9VGH5-1", "name": "", "aln": "MSNADVQFNYGQQGNGDNFNDDSNQQQDEDDQYNEDGGGKIENVGESPKFVRLRGLPWSATHKEILDFLENVNVTNGSAGIHLVTSRVDGKNTGEAYVEVASQEDVEEARKLNKASMGHRYIEVFTATPKEAKEAMRKISGHG----TAFVVKLRGLPYAVTEQQIEEFFSGLDIKTDREGILFVMDRRGRATGEAFVQFESQDDTEQALGRNREKIGHRYIEIFRSSIAEMKRATGAGGG--VGGRPGPYDIRDRGANRGGNDFGGGRNDWGNNGNFGVGANNMLGFNNLPSLMNSGNFGNNQGGNNGNFGNNSGPSNFGNFGGGNNGGNSGNFGNDSGNSGNFGNFGNNGGGNFGGNNNGGGGFNSGNNFNSPGGVNNFGNNGGSNFGGNGGGGFNNGGNFVSSSGVGNFGPIGGGRNNNNGNFGNSGFGNFGGNNNVGSNFGGGNNGGGGGFNNGSNFGGGNSMGGGGNFGPIGGGRGNDIEYYTIHMRGLPYTSFENDVFKFFEPIRPANVRINYNKKGLHSGTADAYFDTYEDSQVAMKRHREQMGSRYIELFYDG-------------------KTRGLNGGEHG-------------------------GGNGGGGMGNNGGGNFSRRI----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .*::******.: .:: *:.. .: .. .::: :* *: :***:**: *::::: * * :: :*****:***.: * . .::: . : .*:*****:. ::::* :*****:* .: *: : :* .*: ******** **: :*:** :::*:*******:*:** *:: . ****** * * .: ..: .: . *. * . :.:. ..*: : :******* : * *:::**.*:.* .*:*: . .* :* **. * *:*:: .** :.: :* **:*** : .* * ..* :. . .* .:.. ..:. ", "identical_positions": 113, "similar_positions": 131, "identity": "17.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2752", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PQS0-1", "uniprot_id": "PKHM1_RAT", "id": "Q5PQS0-1", "name": "Pleckstrin homology domain-containing family M member 1", "aln": "---MLS---VENGLDPRAAIQVIKKKLVGSVKALQKQHVSLDTVVTSEDGDANTMCSALEAVFIHGLHAKYIRAEAGGKRKKHTHQKPLPQPVFWPLLKAVTHKHIISDLEHLVFINTDVGRCRAWLRLALNDGLMECYLKLLLQEPARLCEYYQPTALLRDAEEAEFLLSFLQGLTS-LSFELSYKSAILNEWTLTPLSLSGLCPLSELDPLTVSGAELQRKESLDSISHSSGSE---DIEVQHSGHKIRRD--------RKLTASSLSLDTAS-SSQLSCSLNSDSCLLQENGPKSPDHSEEPMSYDSDLGTANADDSDRSLQEVLSEFSKAQVNSAPSSGPSQESDTPMFQTPLSLHSLANSTHLLFEGSEEPFPAHTSSGTSSG-HKHQ--PQESPDMQPLGTAQAGPAGSTSDQQPSSPVAGAA---DQGSEPWKALEYGRVGPKLVVSSPTSPKGKSWISEDDFCRPPKEHALKNTSDLCISPLQGTPEL-RTALHGPFSQGPRKSCSLGALDKACVSSLDYRNAQTAPSPA------------VTQDHKNFCVVHRRQMGLSNPFRGLMKLGTVARRGAMGIWKEFFCELSPLELRLYLSDEERTCVESCSLLRCEAVGPAHS-DGRFELVFSGKKLALRASSQDEAEDWLDRVREALQKVRPQQEEEWVNIQYPDQAEDSPEAPPDNLPPYSALLPEHAGAQGIQPNWTSAQVPEPDAIKESLLYLYAD-RTWIPYIFSLSLESLKCFRVRNNEKMLSDSHGVETIRDILPDTSLGGPAFFKIITAKAVLKLQAKNTEEAAHWRDLVRKVLASYLESVQE---AVTLAGSLDENCQEVLKFATRENGFLLQYLVAIPTEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDFCHQDDASVIPARIIHNWDLTKRPVCRQALKFLAQIRAQPLINLQLVNASLYEHVERMHLIGRSREQLKLLGDYLGLCRSGALKELSKRLSHRNYLLESPHKFSVADLQQIAEGVYEGFLKALIEFASQHVYHCDLCTQRGFICQICHHQDIIFPFEFDTTVRCAECRTVFHQSCQAVVRKGCPRCARRRKYQEQNTVS------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TSI1-1", "uniprot_id": "PKHM1_MOUSE", "id": "Q7TSI1-1", "name": "Pleckstrin homology domain-containing family M member 1", "aln": "---MLS---VENGLDPRAAIQVIKKKLVGSVKALQKQHVSLDTVVTSEDGDANTMCSALEAVFIHGLHAKHIRAEAGGKRKKHTHQKALPQPVFWPLLKAITHRHIVSDLEHLVFINTDVGRCRAWLRLALNDGLMECYLKLLLQEPARLCEYYQPTALLRDAEEAEFLLSFLQGLTS-LSFELSYKSAILNEWTLTPLSLSGLCPLSELDPLTTSGAELQRKESLDSISHSSGSE---DIEVQHSGHKIRRN--------RKLTASSLSLDTAS-SSQLSCSLNSDSCLLQENGPKSPDHSEEPMSYDSDLGMANTDDPDRSLQEVLSEFSKAQVNSAPSSGPNQEPDTPMFQTPLSLHSLATSTHLHFEGSEELFPAHKSSGTSSGGHKHQLLPQETPDEKQLGTAQAGPAQSTSDQQPSSPVGGAA---GQGSGPWKALEYGRVGPKLVVSSPTSPKGKSWISEDDFCRPPQEPALKSAAGLCTSPVQDTPES-RAALHGPFSQGPRKSCSLGALDKACVPSQACGNAQPAPAPAPAPAPAPAPAPGVTQDHKNFCVVHRRQMGLSNPFRGLMKLGTVARRGAMGIWKEFFCELSPLEFRLYLSDEERTCVESCSLLRCEAVGPAHS-DGRFELVFSGKKLALRASSQDEAEDWLDRVREALQKVRPQQEDEWVNIQYPDQAEDAPEAPPDSLPPYSTLLPEPAGAQGMQLDWTSAQVPEPDAIKESLLYLYAD-RTWVPYIFSLSLESLKCFRVRNNEKMLSDSHGVETIRDILPDTSLGGPAFFKIITAKAVLKLQAKNTEEATHWRDLVRKVLASYLESAEE---AVTLGGSLDEKCQEVLKFATRENGFLLQYLVAIPTEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDFCHQDDASVIPARIIHNWDLTKRPVCRQALKFLAQIRAQPLINLQLVNASLYEHVERMHLIGRSREQLKLLGDYLGLCRSGALKELCKRLSHRNYLLESPHRFSVADLQQIAEGVYEGFLKALIEFASQHVYHCDLCTQRGFICQICHHQDIIFPFEFDTTVRCAECRTVFHQSCQAVVRKGCPRCARRRKYQEQNVVS------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y4G2-1", "uniprot_id": "PKHM1_HUMAN", "id": "Q9Y4G2-1", "name": "Pleckstrin homology domain-containing family M member 1", "aln": "---MLSV--VENGLDPQAAIPVIKKKLVGSVKALQKQYVSLDTVVTSEDGDANTMCSALEAVFIHGLHAKHIRAEAGGKRKKSAHQKPLPQPVFWPLLKAVTHKHIISELEHLTFVNTDVGRCRAWLRLALNDGLMECYLKLLLQEQARLHEYYQPTALLRDAEEGEFLLSFLQGLTS-LSFELSYKSAILNEWTLTPLALSGLCPLSELDPLSTSGAELQRKESLDSISHSSGSE---DIEVHHSGHKIRRN--------QKLTASSLSLDTAS-SSQLSCSLNSDSCLLQENGSKSPDHCEEPMSCDSDLGTANAEDSDRSLQEVLLEFSKAQVNSVPTNGLSQETEIPTPQASLSLHGLNTSTYLHCEAPAEPLPAQAASGTQDGVHVQEPRPQAP---SPLDLQQP--VESTSGQQPSSTVSETAREVGQGNGLQKAQAHDGAGLKLVVSSPTSPKNKSWISEDDFYRPSREQPLESASDHPIASYRGTPGS-RPGLHRHFSQEPRKNCSLGALDQACVPSPGRRQAQAAPSQG----------------HKSFRVVHRRQMGLSNPFRGLMKLGTVERRGAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCESVGPAHS-DGRFELVFSGKKLALRASSQDEAEDWLDRVREALQKVRPQQEDEWVNVQYPDQPEEPPEAPQGCLSP-SDLLSEPAALQGTQFDWSSAQVPEPDAIKESLLYLYMD-RTWMPYIFSLSLEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVLKLQAGNAEEAALWRDLVRKVLASYLETAEE---AVTLGGSLDENCQEVLKFATRENGFLLQYLVAIPMEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRRREQLKLLGDYLGLCRSGALKELSKRLNHRNYLLESPHRFSVADLQQIADGVYEGFLKALIEFASQHVYHCDLCTQRGFICQICQHHDIIFPFEFDTTVRCAECKTVFHQSCQAVVKKGCPRCARRRKYQEQNIFA------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q8H1-1", "uniprot_id": "A0A8M9Q8H1_DANRE", "id": "A0A8M9Q8H1-1", "name": "", "aln": "---MLATQTPESGPDAKDVKQWIKGKIAHTLKALQKRYITTDTAVTSEDLEANLLCCALEAVFIHGIKSKFIRSD-GGQVRKGGSRGALPQPVFWALLKTVTHRDVVQELERLSFINSDVGRCRAWVRLALNDGLLECYLTSLLRENSKMSTYYQPGALLLDPEDREVLLTLLQGLAS-LTFQLSYKSAVLNEWTNTPLVLAGLCPPTPADEQHLG---PKRKESWDTVSQSSGGSGGSDWTPESLQRETRRDQIDGCDPSTPLTSSNLSLDTVSGSSHLSSSLSSDS-LLQGQELRSPEK--ERWSCDSEIN-HNEQQKITATEESLMKEDIDVFIPAPDN--LTDTHSVNEHTHIPDASLTSAQDTHHSHITEQSVENISVETKEETIEESEIIVKSTRLKAKNTVSETAEKEKKRESRDSSVDPPS-----VSALTETEETPDPKDTVLSEISAAPSPVETPQHAACRRTTMSVSRKISTDSLYSSCKSTSWISEEDFHKPEDLSISEAYAIIDVTPMNGQVSPVCEADELQPPP--------------------SVVHRRHNGLPNPFRGLLKLGQLERRSAVGMWWDYYCELSPFELRLYVNAEERVCNENLSLLRCEDIHLYSSTEGRFRLTFPNKRIYLRAPSKGEAEDWVDRITEAVNKLRPIMRDEQWEVLHTSSDQEVTSPAPSTPEHTISELPDPP-----QLDWTRHKDPEPDAIKEAVVYQSLEEKGWRCLVLSLSLEILRGFQVREDSKTPLFSLPIGSIRDVVPDVSLGSPAFFKVLTVRDTLTLRAESGEEARGWRSLIRGALDSYLETEDDGAGASAADGAQGGVVHKLVQHRLKGDGELLLHLSVVPIERGLDAQNYRCAGCSRQIGVSLGRGRLCEFSGQQFCDSCHQGDMSIIPSRMLHNWDLKTREVSRQAFKLLTQIEHEPLLNLAVLNPELFEHADIMAKVQNLRQRLRFLGDYVLLCRSGFSKQIQPRLQQRTYLLDNSDVYSVLDLQQIADGHYESYLQSLIQFGSKHVHNCDLCTQRGFICQICNAPDIIFPFQFDVTSRCNVCKTVFHSSCRAQCPV-CPRCIRKQKYLERDLEES-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W293-1", "uniprot_id": "Q9W293_DROME", "id": "Q9W293-1", "name": "", "aln": "MSSLFRSLNHFSSKRENVVKEALINTLNENAREIEFEVKQKSLEVLGVCEQTSALCTTLEALFLHGLKDSFLSATFNVIAGDVERR---PEPSFWAPCMVFMHKQVIEQVQGLSQITSETGQCRAWVRQSLNESVFSSYLNNMRKNGSALSQYYKRNALMRDSEGLETAAKIMESLEAYVQFDLPVNSSLLNHWPDYSLQLSDLWTP-----------------ALKSCPISSGVD----------------------------VASSLGSDIIAIPTPQP---------LQTNELFSESISNSPFGRNSNFGVPELSQRENLDLLIQKFDEMDVINEEQTGGDKAETNETAEQEAPSGS-----------------------------------------------------KTRSRKKSNRQMDSSS--------------FADLDLEAPSLLPQGSNSLSNLMQTSWSG----------------DLEATPTSPTEELTG--SRFFQRSVSVSSSVSLRSPTTDRCS-----------------------------------------YNALLRKHESNRESGAG-WSEIWEKFRASASNLNVAQPQRDTDP--------------------------------------------PISEDLSDLQSLDTNSEFELLTS---------------------------------------------------------------------------------------------------------------------------------------------------------------------EFDMVELQQMVAQLCQLAREPGLDAQGFLCKSCQHPLGIGYSNFQVCAFSGSYYCNSCMDVEMQLIPARIIYNWDFRKYSVSKRAATFLAEFRSHPFLDMQLLNPRIYFASDAMAELQSLRIRLNFIRAYLYTCAPSSIELLQNQFAGREYLYEHIHLYSIADLALIQRGVLCQQLQKAFKLGEAHVLKCRLCHLKGFICEICQSPRVLYPFHISTTFRCLACGAVFHAECLNEKQP-CPKCERIRKREDQGLQEAVQCLKQKNEVA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .. . . : .: . : :: . . * . ::. :* :***:*:**:: ..: : . . : *:* **. .. *:.::.::: * :.::.*:****:* :**:.::..**. : :: : : **: **: *.* * .:::.* : : *:*. :*::**.*. .* *:.* . : .: . *** . .:*.*. * : .: . ** : * . . . :*::. : .: . . . :.. : . . :. . : .: . ... . . . *. : . . :: . :..*:: *... * * : : :: . .* : :: : * :..::. :. :: . :. :: * :. * ***:*. * .*.: :*.. . ::* *** :*: * : : .:**:*:::***: . :.::* .:*:::. .*:::: ::*. :: : * : * :*.:: *: * .. : : :: * ** : . :*: ** * * *: :::.. ** :* ** :****:**: :::**.:..* ** * :*** .* **:* * :* ::. ", "identical_positions": 123, "similar_positions": 257, "identity": "11.04%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2767", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2S1-1", "uniprot_id": "NFIP1_RAT", "id": "Q5U2S1-1", "name": "NEDD4 family-interacting protein 1", "aln": "-------------MALALAALAAVEPACGTGYQQLQN----EEEPGEREQTAGDAPPPYSSISAESAAYFDYKDESGFP----------------------KPPSYN-------VATTLPSYDEAERTK----------------------AEATIPLVPGRD-----------EDFVGRDDFDDADQLR-----IGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKW---------------------------------------ILIVRFSTYFPG----YFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPET-FSNLPRTRVLFIY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BT67-1", "uniprot_id": "NFIP1_HUMAN", "id": "Q9BT67-1", "name": "NEDD4 family-interacting protein 1", "aln": "-------------MALALAALAAVEPACGSRYQQLQN----EEESGEPEQAAGDAPPPYSSISAESAAYFDYKDESGFP----------------------KPPSYN-------VATTLPSYDEAERTK----------------------AEATIPLVPGRD-----------EDFVGRDDFDDADQLR-----IGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKW---------------------------------------ILIVRFSTYFPG----YFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPET-FSNLPRTRVLFIY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R0W6-1", "uniprot_id": "NFIP1_MOUSE", "id": "Q8R0W6-1", "name": "NEDD4 family-interacting protein 1", "aln": "-------------MALALAALAAVEPACGSGYQQLQN----EEEPGEPEQTAGDAPPPYSSITAESAAYFDYKDESGFP----------------------KPPSYN-------VATTLPSYDEAERTK----------------------TEATIPLVPGRD-----------EDFVGRDDFDDTDQLR-----IGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKW---------------------------------------ILIVRFSTYFPG----YFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPET-FSNLPRTRVLFIY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QQT7-1", "uniprot_id": "F1QQT7_DANRE", "id": "F1QQT7-1", "name": "", "aln": "------------------------MSDQRSGYQQLTN----EEESAEGFQQTADAPPPYSSLGASNAAFFEYKEDEVYP----------------------KPPSYN-------VATSLPSYDEAERSK----------------------AEATVPLVTDRD-----------EDFIARDSFEDTDQLR-----VGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLVKW---------------------------------------VLIVRFSTYFPG----YFDGQYWLWWVFLVVGFLLFFRGFVNYSRVRNMADHSMSTLPRTRVLFIY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVJ5-1", "uniprot_id": "Q9VVJ5_DROME", "id": "Q9VVJ5-1", "name": "", "aln": "----------MPHNNQPSPGDDQLGPPKADFSAPPPY----EANVGHGQQVALPAQMPPLALATPDPSQIPIQMQVQLP----------------------SQADLMNAQLPPEIHGKLPTYEEVQMEKSLNGELPPAFLTLPSSQQLPPPPNPLLPPNPLRDGAAAVRSAQPALTFIAIDASDPENSLSTTDNLLGTDIMFITAFIVAFLFNWIGFLMLTCFCHTIAARYGALSGFGLSLAKW---------------------------------------TLIVKHSTDLAS----HEN--SWLWWLICAFGFLISIRALIQYVSIKRSWRL-LSASAQERLLFFY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38356-1", "uniprot_id": "BSD2_YEAST", "id": "P38356-1", "name": "Metal homeostatis protein BSD2", "aln": "MPEQELLIGQEMNTLHAGSSTDGINVGNAGRTRDTQTGVEGETEIGSDEEDSIEDEGSSSGGNSTTERLVPHQLREQAARHIGKIGRHFNILDRLFKKRTQQSSDIQQGAMFDGVFSNLSAKPDTTETEG--------------------NNEQDIPPTYDEAAADMAPSYYG-MDLNNSDIYYDEICIEG--LPVGNIANLLWNIIVSTSFQFIGFLITYILHTSHAAKQGSRFGLGLTFIGYGYSMIPNDVTSKVGKNKSLNRMELEDPNEFDDVRLNSQSTTQDKFESHLNHGLDEEKQNIPWLAVFVAFLGLFITLKSIYDYIQVKKLEKKYLNQSQNQA-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . : : . . : . : . . .. : .*.: :. : : :* . : * : :*. :: :::: *::***:: : : *.: *: *:**:: : :..: : : ** .. .*::: ::.: :* ::. :. . ", "identical_positions": 18, "similar_positions": 69, "identity": "5.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2768", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K3P5-1", "uniprot_id": "CNOT6_MOUSE", "id": "Q8K3P5-1", "name": "CCR4-NOT transcription complex subunit 6", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MP---------KEKYEPPDPRRMYTIMSSEEAANGKKSHWAELEISG---------------------------------------------------------------------------------------------------------------------------------------KVRSLSSSLWSLTHLTALHLSDNSLSCIPSDIAKLHNLVYLDLSHNQIQSLPAELGNMVSLRELHLNYNQLRVLPFELGKLFQLQTLSLKGNPLTQDILNLCLEPDGTRRLLNYLLDNLSGT-------AKRISTEQPPPRSWIMLQEPDRTRP----TALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIISLQEVETEQYYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFN--QLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKELIEMSSGKPHLGTEKQLILVANAHMHWDPEYSDVKLVQTMMFLSEVKNIIDKAS-RSLK-SSVLGECGTIPLVLCADLNSLPDSGVVEYLSTGGVETNHK-DFKELRYNESLTNFSCNGKNGMTNGRITHGFKLKSAYENG-LMPYTNYTFDFKGIIDYIFYSKPQLNTLAILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLELLLPFLPQVNGIHLPGRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AXU9-1", "uniprot_id": "CNOT6_RAT", "id": "Q6AXU9-1", "name": "CCR4-NOT transcription complex subunit 6", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MP---------KEKYEPPDPRRMYTIMSSEEAANGKKSHWAELEISG---------------------------------------------------------------------------------------------------------------------------------------KVRSLSSSLWSLTHLTALHLSDNSLSCIPSDIAKLHNLVYLDLSHNQIQSLPAELGNMVSLRELHLNYNQLRVLPFELGKLFQLQTLSLKGNPLTQDILNLCLEPDGTRRLLNYLLDNLSGT-------AKRISTEQPPPRSWIMLQEPDRTRP----TALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIISLQEVETEQYYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFN--QLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKELIEMSSGKPHLGTEKQLILVANAHMHWDPEYSDVKLVQTMMFLSEVKNIIDKAS-RSLK-SSVLGECGTIPLVLCADLNSLPDSGVVEYLSTGGVETNHK-DFKELRYNESLTNFSCNGKNGMTNGRITHGFKLKSAYENG-LMPYTNYTFDFKGIIDYIFYSKPQLNTLAILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLELLLPFLPQVNGIHLPGRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ULM6-1", "uniprot_id": "CNOT6_HUMAN", "id": "Q9ULM6-1", "name": "CCR4-NOT transcription complex subunit 6", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MP---------KEKYEPPDPRRMYTIMSSEEAANGKKSHWAELEISG---------------------------------------------------------------------------------------------------------------------------------------KVRSLSASLWSLTHLTALHLSDNSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLFQLQTLGLKGNPLTQDILNLYQEPDGTRRLLNYLLDNLSGT-------AKRITTEQPPPRSWIMLQEPDRTRP----TALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQEVETEQYYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFN--QLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLGTEKQLILVANAHMHWDPEYSDVKLVQTMMFLSEVKNIIDKAS-RNLK-SSVLGEFGTIPLVLCADLNSLPDSGVVEYLSTGGVETNHK-DFKELRYNESLTNFSCHGKNGTTNGRITHGFKLQSAYESG-LMPYTNYTFDFKGIIDYIFYSKPQLNTLGILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLELLLPFLPQVNGIHLPGRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TA39-1", "uniprot_id": "A0AB32TA39_DANRE", "id": "A0AB32TA39-1", "name": "poly(A)-specific ribonuclease", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MMKDQKRLATCLITGMP---------KEKYDPPDPRRMYTIMSSEEAANGKKSTWAELEIVG---------------------------------------------------------------------------------------------------------------------------------------KVKSLSSALWSLTHLTALYISDNSLSRIPPDIAKLNNLVYLDLSSNKIRSLPAELGNMINLRELLLNNNQLRVLPFELGKLFQLQTLGLKGNPLAQEILNLYQEPDGTRRLLNYLLDNLAG--------TKRAPIEQPPPRSWIPLQEPDRTRP----AALFSVMCYNVLCDKYATRQLYGYCPSWALNWEYRKKSIMQEILSCSADIISLQEVETEQYYNYFLLELKEQGYEGFFSPKSRARTMSESDRKHVDGCAVFYKTDKFSLVQKHTVEFN--QLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKEMMELSAGKPLHGMEKQLLLVANAHMHWDPEYSDVKLVQTMMFLSEVKNIVDKAT-RSLKLSSVSGETNAIPLVLCADLNSLPDSGVVEYLSTGGVDGAHK-DFKELRYIDSLTNFNCNGKNGTSSTRITHGFKLKSAYENG-LMPYTNYTFDFKGIIDYIFYSQPLLNVLGVLGPLEHHWLLENNVTGCPHPHIPSDHFSLFAQLELLLPFPPAVNGIHLPGRR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IMX1-1", "uniprot_id": "Q8IMX1_DROME", "id": "Q8IMX1-1", "name": "poly(A)-specific ribonuclease", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MCIFKKRDAYHQAVIMKGNHYKMSRNKDKYDSAN-RRQQIFLSQEDIAAGKKTNWSGLEITG---------------------------------------------------------------------------------------------------------------------------------------CVRNISPSLWEFEHLTALYLNDNQLLRLPADVGMLTSLRTLDLSSNKLRSLPAELGELIQLRELLLNNNFLRVLPYEIGKLFHLVILGLMGNPLQKEFMNIYNEPNGTQKLLTYMLDNLS------------FTVNPPPQRPWLPLAKPNKTRP----ACIFTVMCYNVLCDKYATRQMYGYCPSWALCWEYRKKSIIDEIRHYAADIISLQEIETEQFYHFFLPELKNDGYEGIFSPKSRAKTMSELERKYVDGCAIFFRASKFTLIKESLIEFN--QLAMANAEGSDNMLNRVMPKDNIGLAALLKVKENAWEPMSEVTQIS---QPLLVCTAHIHWDPEFCDVKLIQTMMLSNELKTIIDEAS-HSFR-PGHKNDSNAVQLLLCGDFNSLPDSGVVEFLGKGRVSMDHL-DFKDMGYKSCLQRLLSNDTN-----EFTHSFKLASAYNED-IMPHTNYTFDFKGIIDYIFYTKTGMVPLGLLGPVSNDWLRENKVVGCPHPHIPSDHFPLLVELELMHTASQQAPPNGLINRR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P31384-1", "uniprot_id": "CCR4_YEAST", "id": "P31384-1", "name": "CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4", "aln": "MNDPSLLGYPNVGPQQQQQQQQQQHAGLLGKGTPNALQQQLHMNQLTGIPPPGLMNNSDVHTSSNNNSRQLLDQLANGNANMLNMNMDNNNNNNNNNNNNNNNGGGSGVMMNASTAAVNSIGMVPTVGTPVNINVNASNPLLHPHLDDPSLLNNPIWKLQLHLAAVSAQSLGQPNIYARQNAMKKYLATQQAQQAQQQAQQQAQQQVPGPFGPGPQAAPPALQPTDFQQSHIAEASKSLVDCTKQALMEMADTLTDSKTAKKQQPTGDSTPSGTATNSAVSTPLTPKIELFANGKDEANQALLQHKKLSQYSIDEDDDIENRMVMPKDSKYDDQLWHALDLSNLQIFNISANIFKYDFLTRLYLNGNSLTELPAEIKNLSNLRVLDLSHNRLTSLPAELGSCFQLKYFYFFDNMVTTLPWEFGNLCNLQFLGVEGNPLEKQFLKILTEKSVTG-LIFYLRDNRPEIPLPHERRFIEINTDGEPQREYDSLQQSTEHLATDLAKRTFTVLSYNTLCQHYATPKMYRYTPSWALSWDYRRNKLKEQILSYDSDLLCLQEVESKTFEEYWVPLLDKHGYTGIFHAKARAKTMHSKDSKKVDGCCIFFKRDQFKLITKDAMDFSGAWMKHKKFQRTEDYLNRAMNKDNVALFLKLQHIPS--------------GDTIWAVTTHLHWDPKFNDVKTFQVGVLLDHLETLLKEETSHNFR-----QDIKKFPVLICGDFNSYINSAVYELINTGRVQIHQEGNGRDFGYMSEKN--------------FSHNLALKSSYNCIGELPFTNFTPSFTDVIDYIWFSTHALRVRGLLGEVDPEYVS--KFIGFPNDKFPSDHIPLLARFEFMKTNTGSKKV-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * : : .. : * : : :: * : .:*. ::. .** *::..*.* :*.:: * .* **** *:: *******. ..*: : : * : .**:*:*:* :* *.: **** :::::: * . * *: *: ** . : * * : * :. . . *:*:.**.**::*** ::* * ***** *:**:: : ::* :*::.***:*:: : ::: *.: ** *:* .*:**:** . : * ****.:*:: .:*.*: : ::*. : : : :: ***.* ***:.: *: . : : . .:*:****:: *** .*. :: ..::.::.: : :.:: : . :::*.*:** :*.* * :..* *. : : ::: * . ::*.: * *:*: :*.**:* .*..:****::: : .:** :. .:: :. * *: :****:.*:..:*:: . ", "identical_positions": 140, "similar_positions": 199, "identity": "15.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2772", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96EU7-1", "uniprot_id": "C1GLC_HUMAN", "id": "Q96EU7-1", "name": "C1GALT1-specific chaperone 1", "aln": "MLSESSSFLKGVMLGSIFCALITMLGHIRIGHGNRMHHHEHHHLQAPNKEDILKISEDERMELSKSFRVYCIILVKPKDVSLWAAVKETWTKHCDKAEFFSSENVKVFESINMDTNDMWLMMRKAYKYAFDKYRDQYNWFFLARPTTFAIIENLKYFLLKKDPSQPFYLGHTIKSGDLEYVGMEGGIVLSVESMKRLNSLLNIPEKCPEQGGMIWKISEDKQLAVCLKYAGVFAENAEDADGKDVFNTKSVGLSIKEAMTYHPNQVVEGCCSDMAVTFNGLTPNQMHVMMYGVYRLRAFGHIFNDALVFLPPNGSDND", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JMG2-1", "uniprot_id": "C1GLC_MOUSE", "id": "Q9JMG2-1", "name": "C1GALT1-specific chaperone 1", "aln": "MLSESSSFLKGVMLGSIFCALITMLGHIRIG--NRMHHHEHHHLQAPNKDDISKISEAERMELSKSFRVYCIVLVKPKDVSLWAAVKETWTKHCDKAEFFSSENVKVFESINMDTNDMWLMMRKAYKYAYDQYRDQYNWFFLARPTTFAVIENLKYFLLKKDQSQPFYLGHTVKSGDLEYVSVDGGIVLSIESMKRLNSLLSVPEKCPEQGGMIWKISEDKQLAVCLKYAGVFAENAEDADGKDVFNTKSVGLFIKEAMTNQPNQVVEGCCSDMAVTFNGLTPNQMHVMMYGVYRLRAFGHVFNDALVFLPPNGSEND", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FBK8-1", "uniprot_id": "E7FBK8_DANRE", "id": "E7FBK8-1", "name": "", "aln": "MMSEGSSFMKGMIFGGIFCLIMSFFETFNPGTHSEGHNHLHHHLKPVSKDELQKLSESQMSEFAMQVRVYCLIMVTPKLLVHWATANDTWSKHCDKSVFYTSEASKALDAVDLQEQDEWTRLRKAIQHAYENAGDLH-WFFIARPTTFAIIENLKYLVLDKDPSQPFYIGHTEKSGELDYVEYDSGIVLSYEAMRRLMEVFKDEDKCPERGRALWKMSEEKQLATCLKYSGVFAENGEDAQGKGLFNKKSVSSLISDSISQNPGDVVEACCSDMAITFAGMSPSQIQVLMYGVYRLRPYGHDFHDSLTFLPPKDSDND", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:**.***:**:::*.*** ::::: :. * .. *:* ****:. .*::: *:** : *:: ..****:::*.** : **:.::**:*****: *::** *.::::::: :* * :*** ::*::: * : ***:*******:******::*.** *****:*** ***:*:** :.***** *:*:** .::. :****:* :**:**:****.****:******.***:**.:**.***. *.:::: :*.:***.******:** *::*.*::*:********.:** *:*:*.****:.*:**", "identical_positions": 163, "similar_positions": 111, "identity": "51.26%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2773", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M0K4-1", "uniprot_id": "A0ABK0M0K4_RAT", "id": "A0ABK0M0K4-1", "name": "E3 ubiquitin-protein ligase TRIM33", "aln": "MAENKGGGEAESGGGGSGSAPVTAGAAGPTAQEAEPPLAAVLVEEEEEEGGRAGAEGGAAGPDDGGVAAASSSSAPAASVPAASVGSAVPGGAASTPAPAPVPVPVPVPVPAPAPAPAPAPAPAPGPSSGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIP-----GGSNGDVQQVGVIRCPVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVS-ESVGTSG--QRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIESKPAPGYTPNVVVG-QVPPGTNHISKTPGQINLAQLRLQHMQQQVYAQKHQQLQQMRLQQPPAPVPTTTTTTQQ-------------------------------HPRQAAPQMLQQQPPRLISVQTMQRGNMN--CGAFQAHQMRLAQNAARIP-GIPRHSGPQYSMMQPHLQRQHSNPGHAGPFPVVSAHN--PINPTSPTTATMANAN--RGPTSPSVTAIELIPSVTNPENLPSLPDIPPIQLEDAGSSSLDNLLSRYISGSHLPPQPTSTMNPSPGPSALSPGSSGLSNSHTPVRPPSTSSTGSRGSCGSSGRTAEKSAHSFKSDQVKVKQEPGTEEEICSFSGAVKQEKTEDGRRSACMLSSPESSLTPPLSTN--LHLESELDTLTSLENHVK--TEP--ADISESCK----------QSGLSSLVNGKSPIRNLMHRSARIGGDGN------SKDDDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFP--SGDWICTFCRDIGKPEVEYDCDNMQHSKKGKTAQGLSPVDQRKCERLLLYLYCH-ELSIEFQEPVPVSIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFN-------------------EMMKVVQVYADTQEINLKADSE------VAQAGKAVALYFEDKLS--EIYSDRTFAPLPEFE-QEEDDG-------EVTEDSDEDFIQPRRKRLKSD-ERPVHIK--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PP7-1", "uniprot_id": "TRI33_MOUSE", "id": "Q99PP7-1", "name": "E3 ubiquitin-protein ligase TRIM33", "aln": "MAENKGGGEAESGGGGSGSAPVTAGAAGPTAQEAEPPLAAVLVEEEEEEGGRAGAEGGAAGPDDGGVAAASSSSAPAASVPAASVGSAVPGGAASTPAPAAAPAPAPA--PAPAPAPAPAPAPAPGSSSGPPLGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIP-----GGSNGDVQQVGVIRCPVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVS-ESVGTSG--QRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIESKPAPGYTPNVVVG-QVPPGTNHISKTPGQINLAQLRLQHMQQQVYAQKHQQLQQMRLQQPPAPIPTTTATTQQ-------------------------------HPRQAAPQMLQQQPPRLISVQTMQRGNMN--CGAFQAHQMRLAQNAARIP-GIPRHSAPQYSMMQPHLQRQHSNPGHAGPFPVVSAHN--PINPTSPTTATMANAN--RGPTSPSVTAIELIPSVTNPENLPSLPDIPPIQLEDAGSSSLDNLLSRYISGSHLPPQPTSTMNPSPGPSALSPGSSGLSNSHTPVRPPSTSSTGSRGSCGSSGRTAEKSAHSFKSDQVKVKQEPGTEEEICSFSGAVKQEKTEDGRRSACMLSSPESSLTPPLSTN--LHLESELDTLTGLENHVK--TEP--TDISESCK----------QSGLSNLVNGKSPIRNLMHRSARIGGDGN------SKDDDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFP--SGDWICTFCRDIGKPEVEYDCDNMQHSKKGKTAQGLSPVDQRKCERLLLYLYCH-ELSIEFQEPVPVSIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFN-------------------EMMKVVQVYADTQEINLKGDSE------VAKAGKAVALYFEDKLS--EIYSDRTFTPLPEFE-QDEDDG-------EVTEDSDEDFIQPRRKRLKSD-ERPVHIK--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPN9-1", "uniprot_id": "TRI33_HUMAN", "id": "Q9UPN9-1", "name": "E3 ubiquitin-protein ligase TRIM33", "aln": "MAENKGGGEAESGGGGSGSAPVTAGAAGPAAQEAEPPLTAVLVEEEEEEGGRAGAEGGAAGPDDGGVAAASSGSAQAASSPAASVGTGVAGGAVST------------------PAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIP-----GGSNGDIQQVGVIRCPVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVS-ESVGASG--QRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIESKPAPGYTPNVVVG-QVPPGTNHISKTPGQINLAQLRLQHMQQQVYAQKHQQLQQMRMQQPPAPVPTTTTTTQQ-------------------------------HPRQAAPQMLQQQPPRLISVQTMQRGNMN--CGAFQAHQMRLAQNAARIP-GIPRHSGPQYSMMQPHLQRQHSNPGHAGPFPVVSVHNT-TINPTSPTTATMANAN--RGPTSPSVTAIELIPSVTNPENLPSLPDIPPIQLEDAGSSSLDNLLSRYISGSHLPPQPTSTMNPSPGPSALSPGSSGLSNSHTPVRPPSTSSTGSRGSCGSSGRTAEKTSLSFKSDQVKVKQEPGTEDEICSFSGGVKQEKTEDGRRSACMLSSPESSLTPPLSTN--LHLESELDALASLENHVK--IEP--ADMNESCK----------QSGLSSLVNGKSPIRSLMHRSARIGGDGN------NKDDDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFP--SGDWICTFCRDIGKPEVEYDCDNLQHSKKGKTAQGLSPVDQRKCERLLLYLYCH-ELSIEFQEPVPASIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFN-------------------EMMKVVQVYADTQEINLKADSE------VAQAGKAVALYFEDKLT--EIYSDRTFAPLPEFE-QEEDDG-------EVTEDSDEDFIQPRRKRLKSD-ERPVHIK--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6E2N3-1", "uniprot_id": "TRI33_DANRE", "id": "Q6E2N3-1", "name": "E3 ubiquitin-protein ligase TRIM33", "aln": "-MEVEASGTEDNGDGGAKEPEAVVSIDTETKEAADEAKSQETVPQTPTTSSDSSSSGGGGEATDGTPNAESADPPPPPPPPPPPPPSTPADSTAAAASP-------------AVLTEMSPPPPASTSSSSSTPAAPINLLDTCAVCKQSLQNR-DCEPKLLPCLHSFCLKCIPQPDRKITMPVQ-----GPHGQDTRIVNVMRCTVCHQDYKQIDMVDNYFVKDTSEATNTSVENSTQVCTSCEDNASAIGFCVECGEWLCKTCIEAHQRVKFTKDHKIRKKEEVSPESVGTSG--QRPVFCPVHKQEALKLFCETCDTLTCRDCQLLEHKEHRYQFLDEACQNQKGIIATFMTKLQEKRGLVEYSASEVQKRLKEVAETHKKVEHEIKIAVFTLINEINKKGKSLLQQLESVTKDRSMKLLSQQRDISVLAQQIIHVLNFTNWAITNGSSTALLYSKRLITYQLRLIMKARVDAVPPANGAVRFFCDPTFWAKNVVNLGNLVIEKVAPTAPPSNMMVNQQISPGHNHPGKHSGQINLAQLRLQHMQQAAIAQKHQQQHQHHQQQQHQHQHQQQQQQQQQQQQQQQQQQQQQQHQQQIQQQMRIASQMSQHPRQGAPQMIQQPPPRLISMQALHRGGVNGSSHMFPPHHLRMVSAQNRMPSAQPRLNGQPYPMMQPQLQRQHSNPGHAGPFPVASLHNISAANPTSPTSASMANAHMHRGPSSPVITPIELIPSVTNPENLPCLPDIPPIQLEDAGSSTLDNILSRYISANAYP--TVGPTNPSPGPSTHSPGSSGLSNSHTPARPSSTSSTGSRGSSGTT------------VDQVKVKQEPGVEEECSYSGANVKTERTKDGRRSACMMSSPEGSLTPPLPILGSVSTGSVQDILRTLGENVK--SEPQSDNLSSCTN----------PNSRATLTNGTSGSNGGQRGGATNANSQTTA----GKEDDPNEDWCAVCQNGGELLCCDHCPKVFHITCHIPTLKSSP--SGDWMCTFCRNLANPEIEYNCDDDPPRNKEKNEMAMSPEEQRRCERLLLHVFCH-ELSTEFQEPVPTSVPNYYKIIKHPMDLTLVKRKLQRKHPLHYKSPKEFVSDVRLVFSNCAKYN-------------------EMSRIIQVYDEEKQSNVQADSE------VAEAGKAVSLYFEERLL--EIFPEQTFPVVMEKETQIEAEK-------EDSDDSDDDIIQPKRKRLKVDTEMLLHIK--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KGE5-1", "uniprot_id": "A0A0B4KGE5_DROME", "id": "A0A0B4KGE5-1", "name": "", "aln": "-----------------------MDMDLEQLKNDFLPLIAGIKQEQ--------------------LDAVPTDALPQMSTPNTASGAPTTSSLSSSS-----------------LSLSNPCDSAEKRSESNSSASAKFTLFKCVYCAQLLGSN--DRPKLLECLHVACAQCVSTKFSELDRSLPPLIHCPVCDNASQQEFIVDNQFLIEQCTAGDSGDGVGLLGLTGEGQKSSAAASIQCSSCSDGAVATSWCVDCSEYICDSCVQAHQRLKITKDHTIKPKDEANNEQLAGAAGVDKLHMCQLHPQEKLSLFCETCDKLTCRDCQLSDHRDHKYKFAHEIATESRQALSTLVSEINYKRFLLSSATKVIDDRQQLIHDKKKDLIKEITAMAVKITNTVNTRGKQLIMRLNEVCDSKLKVLVEKKETLQLLSDNTDHCIDFMQNALEKGSDFAILSSKKSLVRHLQKLKCQRAD-IPNPEIPVRIQVQLNQVSDLQKVISQLGIIIVDGKPYPPTPSPN--GTPQPQHPPRQPPSPNMAPPLRPGLPPGMPAGLSPNGPPVNFGPQNGPPLYSNAAQQQFNNLSMSRSFPGDGSGKVRFGGMPPVG----MQRHGQPHVSSSTHP--QNMDISLRGLLN-NQAAQSPNAHMAFNGPPSYPGGPQGAPAPAHQPMGPQMR-PHFMPGQQG-FSQGGGPGGGPRDANFMNSNARFQSQYQRMANHAQQAAAAAAMAGAAGGGGGQIPSPGALQRPQMMSNPMQNVSAMQNSLGFHG--SQAGFNTGPPQTSPQLGGGGMHSLAKWHIPQSAQQSNMCSQQGPLLPFANGRQTSENFKISLKSPNTLKNSTPPSLGGGGAGHQGHGNGSSSAQLNAAALGLGPAVSILSNVTSTNPKTPSPSTHENTKDFTEPIDKVRDDSINDLIATIAKLDSNGVQVLPEGRTKTTSPQVHSSTDLSNTQEVNNKNEQKDDPNEDWCAVCLDGGELMCCDKCPKVFHQNCHIPAISSLPDESESWQCLLCVNIKELTKTEGSEKSSSGE-------LSALELRILQRICLELYCQYEQSLNFREPESPANTSYYEIVSSPMSLDVIRTRLDPSSPNHYKDIAGFVSDVRLIFSNTYLFYQEDTKTYSNAKYLENFFEEQLAKWLPQFEGTKPQGKRNTSNSPALLGVNATGSPSPIENGRKSCGSASLGDSDGACLPAKRARRSAHEXNELMPGGKGTDGEQQAETGQERRQEEQQQLPAFLEEMDLEMPQRPHSLGSSVIQESADYVLQLLHAYAAAFGL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : * .:.. . * .. : ... :: : . .* * . . ... * .*. * * * .. .**** *** * :*:. :: .: . : :: . :: * *. : . : ..* : *:**.*.* * .:**:*.*::*.:*::****:*:**** *: *::.. *.:. :. :: :* :* ** *.******* ******** :*::*:*:* .* :.: : .::::: *: : ::. ::.* : : :.:* : :**. ..: * :*.:**.*: :*:.* ..: *:.::. : *: : * ::* : *: .**. *:* **: :. :*: : * * :* .: .:*: : . :. :.:* * ... . .* :* : . . *:* : * : . ** *:. *:: .. * .:: ** :* .: . * . . : * *::: * **: * *. . . . :.. .: : ::: * .. . :. : : . :*. .:* : *..::*: : * . . . *..* :: . *..*: . . * *:..:. .. *. . . :. :. .. .: ... *:. :.:. .* *.:. : . ::.* ** ... : .. * :* : . .: .. :.*********** :**:*:**::****** .**:*:: * * * .* * :* :: : ..:. : :*. : * :*: * ::*: * * :*:** . : ..**:*:. **.* :: :*: . . **: **:****:*.* : :: : : : : . : *: * :*.. .: : : . : . : . . *.::: :.:* : : : .:: ", "identical_positions": 205, "similar_positions": 373, "identity": "15.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2774", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63767-1", "uniprot_id": "BCAR1_RAT", "id": "Q63767-1", "name": "Breast cancer anti-estrogen resistance protein 1", "aln": "MKYLVSVGAGPARRAGGLEDVSWGPRVSRRPQSYRAARHVNESLPRSAFRVPAAHGASVTPSAALGSGLPETQPEAVCRGTEKPRFAEGCKPAASRDKNVLAKALYDNVAESPDELSFRKGDIMTVLERDTQGLDGWWLCSLHGRQGIVPGNRLKILVGMYDKKPAA--PGPGPPATPPQPQPSLPQGVHTPVPPASQYSPMLP------TAYQPQPDNVYLVPTPSKTQQGLYQAPGPNPQFQSPPAKQTSTFSKQTPHHSFPSPATDLYQVPPGPGSPAQDIYQVPPSAG---TGHDIYQVPPSLDT------------RSWEGTKPPAKVVVPTRVGQGYVYEASQAEQDEYDTPRHLLAPGSQDIYDVPPVRGLLPNQYGQEVYDTPPMAVKGPNGRDPLLDVYDVPPSVEKGLPPSNHHSVYDVPPSVSKDVPDGPLLREETYDVPPAFAKPKPFDPTRHPLILAAPP-PDSPPAEDVYDVPPP---------APDLYDVPPGLRRPGPG-----TLYDVPRERVLPPEVADGSVIDDGVYAVPPPAEREAPTDG-KRLSASSTGSTRSSQSASSLEVVVPGREP-------LELEVAVETLARLQQGVSTTVAHLLDLVGSASGPGGWRSTSEPQEPPVQDLKAAVAAVHGAVHELLEFARSAVSSATHTSDRTLHAKLSRQLQKMEDVYQTLVVHGQVLDSG--------RGGPGFTLDDLDRLVACSRAVPEDAKQLASFLHGNASLLFRRTKAPG-----PGPEGSSSLHLN--------PTDKASSIQSRPLPSPPKFTSQDS-PDGQYENSEGGWMEDYDYVHLQGKEEFEKTQKELLEKGNIVRQGKGQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLVPGRTGGLGPSDRQLLLFYLEQCEANLTTLTDAVDAFFTAVATNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKAADVRSKVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVDRVKELGHSTQQFRRVLGQLAAA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61140-1", "uniprot_id": "BCAR1_MOUSE", "id": "Q61140-1", "name": "Breast cancer anti-estrogen resistance protein 1", "aln": "----------------------------------------------------------------------------------------------MTVPNVLAKALYDNVAESPDELSFRKGDIMTVLERDTQGLDGWWLCSLHGRQGIVPGNRLKILVGMYDKKPVG--PGPGPPATPPQPQPSLPQGVHAPVPPASQYSPMLP------TAYQPQSDNVYLVPTPSKTQQGLYQAPGPNPQFQSPPAKQTSTFSKQTPHHSFPSPATDLYQVPPGPGSPAQDIYQVPPSAG---IGHDIYQVPPSLDT------------RGWEGTKPPAKVVVPTRVGQGYVYEAAQTEQDEYDTPRHLLAPGPQDIYDVPPVRGLLPNQYGQEVYDTPPMAVKGPNGRDPLLDVYDVPPSVEKGLLSSSHHSVYDVPPSVSKDVPDGPLLREETYDVPPAFAKPKPFDPTRHPLILAAPP-PDSPAAEDVYDVPPP---------APDLYDVPPGLRRPGPG-----TLYDVPRERVLPPEVADGSVVDDGVYAVPPPAEREAPTDG-KRLSASSTGSTRSSQSASSLEVVVPGREP-------LELEVAVESLARLQQGVSTTVAHLLDLVGSASGPGGWRGTSEPQEPPAQDLKAAVAAVHGAVHELLEFARGAVSNATHTSDRTLHAKLSRQLQKMEDVYQTLVVHGQVLDSG--------RGSPGFTPEDLDRLVACSRAVPEDAKQLASFLHGNASLLFRRTKAPG-----PGPEGSSSLHPN--------PTDKASSIQSRPLPSPPKFTSQDS-PDGQYENSEGGWMEDYDYVHLQGKEEFEKTQKELLERGNIMRQGKGQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLVPGRTGGLGPSDRQLLLFYLEQCEANLTTLTDAVDAFFTAVATNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVDRVKELGHSTQQFRRVLGQLAAA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56945-1", "uniprot_id": "BCAR1_HUMAN", "id": "P56945-1", "name": "Breast cancer anti-estrogen resistance protein 1", "aln": "----------------------------------------------------------------------------------------------MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRLKILVGMYDKKPAG--PGPGPPATPAQPQP----GLHAPAPPASQYTPMLP------NTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPSAG---MGHDIYQVPPSMDT------------RSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPP-PDSPPAEDVYDVPPP---------APDLYDVPPGLRRPGPG-----TLYDVPRERVLPPEVADGGVVDSGVYAVPPPAEREAPAEG-KRLSASSTGSTRSSQSASSLEVAGPGREP-------LELEVAVEALARLQQGVSATVAHLLDLAGSAGATGSWRSPSEPQEPLVQDLQAAVAAVQSAVHELLEFARSAVGNAAHTSDRALHAKLSRQLQKMEDVHQTLVAHGQALDAG--------RGGSGATLEDLDRLVACSRAVPEDAKQLASFLHGNASLLFRRTKATA-----PGPEGGGTLHPN--------PTDKTSSIQSRPLPSPPKFTSQDS-PDGQYENSEGGWMEDYDYVHLQGKEEFEKTQKELLEKGSITRQGKSQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLAPGRTGGLGPSDRQLLLFYLEQCEANLTTLTNAVDAFFTAVATNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVERVKELGHSTQQFRRVLGQLAAA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PM80-1", "uniprot_id": "A0A8M9PM80_DANRE", "id": "A0A8M9PM80-1", "name": "Breast cancer anti-estrogen resistance protein 1", "aln": "----------------------------------------------------MSVPVFCKMFDCLQGTSAEIGSRPLNPSSAGSAALLDHHLLHSDPLNVLAKALYDNVAESPDELSFRKGDIMTVLERDTQGLEGWWLCSLHGRQGIVPGNRLKILVGMYDKQQQQQLQQLANQPSPTQSLINLPQSAYNKIPPAAQYTAMHPAFTPSGSANSTNPDGVYMLP-PSHGSS-LYQVPSGPPTPQ--PQPKAPALAKKQTHVQYPPTTQDVYQVPPSINAPGQDIYQVPPAAGGQCPGQDVYQVPPSVNQTQDVYQIPPSLDRSWDSPKPMGKVVVPTRVGQVYVYDTGKNEQDEYDVPRHLPP--SQDIYDVPPTR----TQYIQQVYDTPPMAMKGPPSGQ---EIYDTPPSVDKSQ-LHYQQTVYDIPPSVSKDVPDGP-IREETYDVPPHFAKMKSLENQNQAYLSQIPGGPEPPIPEDVYDVPPPQLIGKRQPEGQEIYDIPASLRKGGPQDHHPTDVYDFPRERPAGEDSGD-YVYDVPPQVVRDAAATEELTVSFKRLSASSTGSTRSNLSTSSLDMVPVRESSGPGRLLLLDLDQAMERLSRHQQAVESSVSLLMSFIS-----GNWRS-STQMESNLPAIRQAVDRIRVAVRDLLEFARGAVANATQATDRTLQTKLGKQVQKMEEAFQGLVRYSQALDTLGWSPAALMTSQPGTGGDDLDRLIMCARGVPDDTKQLASFLHGNASLLFKRTNKQQQLPLPPVPHTGDSLTNNNNISAYQSGTPERANIQSRPLPSPPKFSAEEEAPDRPYETTEEGWMEDYDYVHLQGKEEFEKNQRQLLEKGSIK-QNKTQLEQQQLKQFERLEQEVSRPINNDISGWTPPSHYPQTQRSKLCMGDRQLLLFYMEQCEANITTLTNAIDAFYSSINNNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKSPEVRTRVAQHSNTLCDKLKDIVVSTKTAALQYPSPGSTRDMTERVRELAGCTQQFRMALNQLLAM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******************************:*****:****************************: . .:*.*. . : ***:**:.* * .: ..:.*.**::* **: .. ***.*. * * * ::.:::*: .* :*..: *:*****. ..*.********:** *:*:******:: *.*:..** .********** ***::.: ****** **** . .********.* .** *:********:*** . : ::**.****:*. :::***:************ :********* *** *.:: . . : * *:.* .********* . ::**:*..**: ** :**.**** : .* * * .* .* * : . *************. *:***::. ... *:*: *:* *:* **.*.::*: *:.: . *.**. * *. :: ** :: **::******.**..*::::**:*::**.:*:****:..* ** :.*.**: . .* :*****: *:*.**:*:***************:**: * *. ..:* * * : :.************::::. ** **.:* *******************.*::***:*.* *.* *** *****************::*::.***.. : . * .********:******:****:*:***:::: .*********************************:.:**::*:::** *** *:.**.:**:********.:::**.:**:**. .***** .*.** * ", "identical_positions": 484, "similar_positions": 223, "identity": "46.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2784", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AXU6-1", "uniprot_id": "JUPI1_RAT", "id": "Q6AXU6-1", "name": "Jupiter microtubule associated homolog 1", "aln": "MTTTTTFKGVDPN--SRNSSRVLRPPGGGSNFSLGFDEPTEQPVRKNKMASNIFGTPEENPPSW----------------AKSAG-----GREDSESPGTQRSNS----SEASSGD------FLDLKGESDVHEN---VDTDFQASLAQVEEKPVPAAPVPSPVAPAP------------------------APSRRNPPGGKSSLVLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97825-1", "uniprot_id": "JUPI1_MOUSE", "id": "P97825-1", "name": "Jupiter microtubule associated homolog 1", "aln": "MTTTTTFKGVDPN--SRNSSRVLRPPGGGSNFSLGFDEPAEQPVRKNKMASNIFGTPEENPPSW----------------AKSAGSKSSGGREDSESPGTQRSNS----SEASSGD------FLDLKGEGDMHEN---VDTDFQANLAQMEEKPVPAAPVPSPVAPAP------------------------VPSRRNPPGGKSSLVLG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UK76-1", "uniprot_id": "JUPI1_HUMAN", "id": "Q9UK76-1", "name": "Jupiter microtubule associated homolog 1", "aln": "MTTTTTFKGVDPN--SRNSSRVLRPPGGGSNFSLGFDEPTEQPVRKNKMASNIFGTPEENQASW----------------AKSAGAKSSGGREDLESSGLQRRNS----SEASSGD------FLDLKGEGDIHEN---VDTDLPGSLGQSEEKPVPAAPVPSPVAPAP------------------------VPSRRNPPGGKSSLVLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BAY7-1", "uniprot_id": "A0A8M2BAY7_DANRE", "id": "A0A8M2BAY7-1", "name": "", "aln": "MTTTTTFQGMEPG--AKNSSRVLRPPGGASNISFGTEE--EKPVRKNKMASSIFAEPDDPHAHR----------------RNNPPGGEASGVLCGEPSAPLRRCQPAIVYDEGAGE------PQPNHEDHHEYEQENHGESDFPPVEECVEQKEDSSSSSSASAQPSAGN----------------------ASGRRNPPGGKSSLILG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7K0-1", "uniprot_id": "JUPIT_DROME", "id": "Q9I7K0-1", "name": "Microtubule-associated protein Jupiter", "aln": "MAAYAAFKHVELYNVGKAKKRVLRPPGGGSSDIFGSEMPQTPRNVKNRMASNIFAAEKDNGVKNNVRQGAHRFYFIGDAPRRGQKTVDSHSRLFGEPTRPITPGKNHMKSSIPFGQNTEAVAAQKLLTTNGHYNGKSGSVSSASSSVSSSTENLKMNSGSRSEGNPVTGEGYKVVANEYSQRQESSNGGTPVINKNRIPPGGYSSGLW-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: ::*: :: .: ..********.*. :* : **:***.**. .: .. . *.. . . *: :: :. :: : : * . .* **** ** : ", "identical_positions": 29, "similar_positions": 39, "identity": "13.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2785", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZXT2-1", "uniprot_id": "D3ZXT2_RAT", "id": "D3ZXT2-1", "name": "Cohesin subunit SA", "aln": "----------MIAAPEIPTDFNLLQ-ESETHFSSDTD----------------------FEDIEG------------------KNQKQGKGKTCKKGKKGPAEKGKSGNGGGKPPSGPNRMN--GHHQQNGVENMMLFEVVKMGKSA-MQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVTAEMFRHMQNSE---------IIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLVRQC-QYSIIYDEY-----------MMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDAIAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKE-----LNSKLELFTSRFKDRIVSMTLDKE-YDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAGEFLYKKLFSRRDPEEDGIMKRRGRQGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVGRGTG-KRVLTAKEKKTQLDDRTRITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHLDALLRQIRNIVEKHTD-TDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELADKFNRLLEDF---LQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTG-----IENGD--MPEQIVIHALQCAHYVILWQLAKIT----ESTSTKEDLLRLKKQMRVFCQICQHYLTN-VNTTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDSNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQIDKIQCAKTLILSLQQLFNEMIQEN-----GYNFDRSSSTFSGIKELARRFALTFGLDQLKTREA-IAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGMSSRGSTVRSKKSKPSTGKR-KVLEGMQLALPEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMSVYPM--------------QTEHHQTPLDYN--------------------------------------QRGTSIMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMDESVLGVSMF-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35638-1", "uniprot_id": "STAG2_MOUSE", "id": "O35638-1", "name": "Cohesin subunit SA-2", "aln": "----------MIAAPEIPTDFNLLQ-ESETHFSSDTD----------------------FEDIEG------------------KNQKQGKGKTCKKGKKGPAEKGKSGNGGGKPPSGSNRMN--GHHQQNGVENMMLFEVVKMGKSA-MQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVTAEMFRHMQNSE---------IIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLVRQC-QYSIIYDEY-----------MMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDAIAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKE-----LNSKLELFTSRFKDRIVSMTLDKE-YDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAGEFLYKKLFSRRDPEEDGLMKRRGRQGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVGRGTG-KRVLTAKEKKTQLDDRTRITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHLDALLRQIRNIVEKHTD-TDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELADKFNRLLEDF---LQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTG-----IENGD--MPEQIVIHALQCAHYVILWQLAKIT----ESTSTKEDLLRLKKQMRVFCQICQHYLTN-VNTTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDSNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQIDKIQCAKTLILSLQQLFNEMIQEN-----GYNFDRSSSTFSGIKELARRFALTFGLDQLKTREA-IAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGMSSRGSTVRSKKSKPSTGKR-KVVEGMQLALPEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMSVYPM--------------QAEHHQTPLDYN--------------------------------------RRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMDESVLGVSMF-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N3U4-1", "uniprot_id": "STAG2_HUMAN", "id": "Q8N3U4-1", "name": "Cohesin subunit SA-2", "aln": "----------MIAAPEIPTDFNLLQ-ESETHFSSDTD----------------------FEDIEG------------------KNQKQGKGKTCKKGKKGPAEKGKGGNGGGKPPSGPNRMN--GHHQQNGVENMMLFEVVKMGKSA-MQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVTAEMFRHMQNSE---------IIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLVRQC-QYSIIYDEY-----------MMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDAIAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKE-----LNSKLELFTSRFKDRIVSMTLDKE-YDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVGRGTG-KRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHLDALLRQIRNIVEKHTD-TDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELADKFNRLLEDF---LQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTG-----IENGD--MPEQIVIHALQCTHYVILWQLAKIT----ESSSTKEDLLRLKKQMRVFCQICQHYLTN-VNTTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDNNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQIDKIQCAKTLILSLQQLFNEMIQEN-----GYNFDRSSSTFSGIKELARRFALTFGLDQLKTREA-IAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTGKR-KVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMSVYPM--------------QTEHHQTPLDYN--------------------------------------RRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMDESVLGVSMF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IZR5-1", "uniprot_id": "A0A0R4IZR5_DANRE", "id": "A0A0R4IZR5-1", "name": "Cohesin subunit SA", "aln": "----------MIAAPELQTEFHYPQ-DTDTRFSSDTD----------------------FDDPDG------------------RNAIIGKGK-AKKGKKGPGEKGK---GMGK---GVGRMN--GHHQENGMENVMLFEVVRLGKSA-MQSVVDDWIESYKHDRDVALLDLINFFIQCSGCKGVVSGEMFRNMQNSE---------IIRKMTEEFDEDSGDYPLTMTGPQWKKFKSSFCEFIGVLVRQC-QYSIIYDEY-----------MMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYEAERNKMIGKRANDRLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDAIAEIRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYHNRE-----LNAKLELFTSRFKDRIVSMTLDKE-YDVAVQAIKLLTLVLHSSDEVLTAEDCESVYHLVYSAHRPVAVAAGEFLFKKLFSHRDPEDDSMPKRRGRQSVNANLIKTTVFFFLESELHEHAAYLVDSMWDCAAELLKDWECMISLLLDEPLPGEEALTDRQETALIEILLCTIRQAAECHPPVGRGTG-KRVLTAKEKKTQLDDRTRMTELFAIALPALLAKYSVDAEKVTNLLQLPQFFDLEIYTTGRLEKHLDSLLRQIREIVEKHTD-TDVLEACSKTYHSLCNEEFTIFNRVDIARSQLLDEQVDKFNKLLEDF---LQEGEDPDEDDAYQVLSTLKRISAFYNAHDLSKWDLFTSNYKLLNTG-----IENGD--MPEQIVVHALQCTHYVILWSLAKVS----EGCYKKEDMLTLRKQMRAFCLMCQRYLTS-VNTAVKEQAFTILCDLLLIFSHQIISGGREALEPLVYTPEASLQSELLNFILDHVFIDQDEDSNSTDGQQDDEAGKIEALHKRRNLLAAYCKLIIYNVVEMSTGADIFKQYMRYYNDYGDIIKETMSKTRQIDKIQCAKTLILSLQQLFNEMLSEL-----GPSFDRSSSAFCGIKELARRFSLTFGLDQLKTREA-IAMLHKDGIEFAFKEANPQGDGHPPLNLAFLDILSEFSSKLMRQDKRTVHMYLERFMTFQMALQREDCWLPLISYRNSLQAGGDDDTMSVVSGISSRGSSVRSKKAKPATAKR-KLPE-------EESSSSSEVWMSREQSMQTPVMMPSPHLTSTIMREPKRLRPEESYMGVYTMTPDQQQQHTHPHTPQPQHHQTPMDYNTQVTWMLAQRQQQEEVARQQQERAMNYAKLRSNLQHAIRRGTGLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERSELKPDFFDPASIMDESVRSTHFLGYDAFQR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VM62-1", "uniprot_id": "Q9VM62_DROME", "id": "Q9VM62-1", "name": "", "aln": "--MMARRGGKRIRMDDPPPDYEELHSDALNESTSDADSPTKRMTRLRARGGVRDKPPIIDDDEDD------------------FFAPIARKRKTPATRKGPTERKERVERPRKEPVDKGHHERIDSEREITTDENSLYYIVRHSKNP-IASIVDQWIEQYKANRETALVALMQFFINASGCKGKISEDIQYPVDHTS---------IIRRMTEEFDEESGEYPLIMSGTQWRKFKNNFCDFVQTLVKQC-QYSIIYDQF-----------LMDNVISLLTGLSDSQVRAFRHTATLAAMKLMTALVDVALLVSNNFDNAAKQFEAERVKSRDRRASDRLDSLMTKRSELEENMDEIKSMLTYMFKSVFVHRYRDSLPDIRAICMAEIGIWMENYPQNFLDDSYLKYIGWTLHDKIGEVRLRCLQSLLPLYEKDE-----LKGKLELFTSKFKDRIVAMTLDKE-FEVSVHAVKLVISILKIHPEILADKDCEIVYELVYSSHRGVAQAAAEFLNVRLFHLTADMEETKTKRGKVRMPNTPLVRDLVQFFIESELHEHGAYLVDSFID-SNDMVRDWECMTDLLLEEPGPNEEVLDNKQESTLIEIMVSSVKQSATGEVPVGRASNRKCTLSAKELKAIQDEKAKLTEHFIVTLPSLLEKYQADSEKLANLLAVPQYFDLNLYTTNRQEGNLQALLDRINQVMSMHTG-REVLETCAKTLECLCAEGSATYTRCNIARSNIIESAVNKYKDAIEEWRNLIQGEETPNEDDIYNITITLKVLSILYSSHNLNPWELFKSLFQDVEEAQS---KENIDRCLPNEALVYCIEACYFSISWGLQYVEN-ECESVNVTEVVAELRNNLDTFMGACFELTRDGPTVQIQEAAYQSICDLLIIFSDKLARSEIEHIRGLEYKSRMDEHLILDNFVQHYVFSLKQD--------VAQDETRIEELHKKRNFLACYCKLVVYNIIPTMRAASIFKYYVKCYNDYGDIIKATLGKAREINKVNFAMTLLLSLITVFKSLQEQSE----DGIVSKSSQEFVDLKELAKRFALTFGFDAIKNRES-VAAIHRGGIYFAANK-EPDDPVRAPTRLLFLEVLNEFNYKLLKQDKKVIMSFLDKIIPPAMPSSRAEEWQPLILYRNSLLHG-ETDQAPVAS-------------KRAYTRKRR------------------------------------------------------------------------------DHD----------------------------------------------------EEEEE----------EEDEEEHND------------------------PDYRG----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0F4-1", "uniprot_id": "Q9W0F4_DROME", "id": "Q9W0F4-1", "name": "", "aln": "-------------MSDISFDDAVLN---DSQASNQMD----------------------FEIREE------------------CSIAPNDEPVCVDGTVGDATNKS---------------------LLQMILSRKRLSPTNKRNSH-IESVAKYWGEFYLDSPTAALVALLQFVVEVSGSHYQIPDDTSMPFSYSD---------ILSNSSSHFSN-THIYPLIRK--PADVFVNQVGSFLNALLLVANKFRSDSYQL-----------FLVQLTNFVMACSESNIRTFRHTATMIGLKIMTILSDLKS----------------------------------------LDDEIAMTVWMQMFNSMFVARSRDIVTDIRLLCISELGQWFARYPHCHLQPTSLRIFYEALNDGSGDVIQCSLDNISVLCRKDV-----LFSEIVALTSEFREILVELCLGKE-DAIAEKSVQFLTHFHVLSAEILTDDVCRVLEQLIMAANRGLAQAAADLFILRRNGLDG---ETFCQR----------VKHLLQLFIECG-HEQADYLVDSLID-NCELVLDWKSMIAVLLENPKSRE--LSDIHCSSLIAILLAGVKQATAGEIPPGRYTK------DLKREPRQGAQERATKCLAPVLPELLRTYANRLQDIERLLELPKYFCFDYYHEQNRMGQLNELVEHFELIIFDQTSSTTVLQITVKTLEFLNRMIPIPLT------KQLLNSAVTNYKMAWHRT--QDTSPSRSTHNESNRLLATLRLLTVLSGHFNLSKWDLTEPLLFSLKMLLRQRRLPNGDD-LPPEAFSLYLKACFCCLCWDMENLEGTALNNVDMDEYCDVLHHNLEDYLYVTFSLVGKSNTEPLAYPCFSYTCDLFVLHG-NLCGSSNPSIRSVAHVPSGNELDILEGFLMEHFLELSPSD--------LMLETNSDQLQRIRSILTSYLKVVCLGVVPTMRASKFYEYYVKYHAPFGDVMRCSMELALQRNPIHFAMTMLHTCLLLYAKVFPDDTRH-AAGQRALRPAEFSELMELANRLAKILISNPMEHREC-VIALHRSGILFVFELAQKQP-TEATKKLPFLRVLKVFVPLLLVQDKTRILNFFEPYEQLIIPTCNRNDIAHLKEYRNALRPRKTKSYPQAT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40541-1", "uniprot_id": "SCC3_YEAST", "id": "P40541-1", "name": "Cohesin subunit SCC3", "aln": "MTAVRRSTRIRTKSQVIEEDYDDEQNTSAQHVESDKITAKTQHEEEEEQDTGESEESSSEDDYEDQDDDDYVDTATAKRKSRKRKPKSASNTSSKRQKKKPTSAQKSAVSHAPAYHRSKKDQDQYLEIAKDFQPTELFDILSTSEDVSIEELLREWLETYSENRDKFLQEFINLLLNCCGSVARVEDHDVHSNESSNETIGEIQLLFQRQKLHEFYLLISKENKKRKNFKMGPLYQNFAEFMTKLLEVANDLQLLYVESDEDDTQIVTGNLVLDLLTWLSSFSVCKIRCFRYISTLTLYLFQDYLTQQAVNLEKNYLAKLSKQLSLEEKKK-RPNNKTLEKLESTIAETQGSKVVIDSIIDNIVKLCFVHRYKDVSDLIRSESMLHLSIWIKNYPEYFLKVTFLKYFGWLLSDNSVSVRLQVTKILPHLIIQNHNSKSTDNSAIRQVFERFKTKILEVAIRDVNLDVRIHSIQVLTEASSLG--YLDDSEILIISSLMFDEEFDPFKTSSFNKRSKFLSTVAKFLARVIKEKFDEFIKTHEDLPKEVDGLEVGPVVQVGIFIKILNDSLIYHLKDCAEVDSRTKIRMLTQAAEFLSPYISTHLKTICNLLISDTESNELIQKLQN--SANNNSDDEDVDDEELDITPLFPIDR-------------NSTILYLNVFHGLCAGANNPKIQTKDSVKEIVLPLFYDLLNAASIESADILCPLLESFITFSLDDWISIGYETELKKITDKTIKAFMDS-------TIGNSKVDMKYDIFAKFIHHIHHFEKKELQEKFLNQIATLKIHLKKFLQEKMDP-NNSRDDYKDLTCSLYELYINKLTILGRDYPIEVDEELLQLFLNNFVSRIPIMFQDFDDSTAQEINFKMLVLLATWNLEKWREIIEKVRDYENSISKDLRSVWKPIAAIIGRLNTLVISLAATN-----ETFENINSLFYLKWSACTSLMDIIVAIKIFELKLPADATTWRYSMSEQFPFYLHDNASKVLLKIFLYLESLFAKQVDVQLERVADEDANLNDLPETGFFENIETEFLLFTVKLKGLMKLNILDERFASRVALNKEKLGPLFKKIVDDTIMENPE--PNKKNIQKAKSNQTQREKAPLQPNSERETDHANTENNDPDIPMTIDLEPIEESSQNNSELAPIEEHPTVVDAIDNSDEITQD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . .: : : . :. : .: * * * . * ::::.:: .*. : . . :. : . .* : ... .*: *: . . : :: : . : . * .::* **: :*: : * : . .: :.: ** * :* ** .: .:. *: *.. .*. : *: . : * .* : * : . : . ..*: :: : : . : ::::.: * . : *: . ::. : :. :* : ::. : * : * : . . : . :: : : : . : . : . : . . * : :* : :. : : : . :. . : . . :.. . : . . : : : . . : :: : * . : . : : * : ::: . : . : :: . : : : . . : : :: :. :. : :: . . : : : : : :: :: : : :. * . ::: : : : . . :. ::* : : . . . . ", "identical_positions": 39, "similar_positions": 229, "identity": "2.8%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2789", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63564-1", "uniprot_id": "SV2B_RAT", "id": "Q63564-1", "name": "Synaptic vesicle glycoprotein 2B", "aln": "-MDDYR---YR----DNYEGYAP--NDGY-YRGNEQNPEEDAQSDVTEGHDEEDEIYEGEYQGIPHPDDVKSKQTKMAPSRADGLRGQADLMAERMEDEEQLAHQYETIIDECGHGRFQWTLFFVLVLALMADGVEVFVVSFALPSAEKDMCLSSSKKGMLGLIVYLGMMAGAFILGGLADKLGRKKVLSMSLAINASFASLSSFVQGYGAFLFCRLISGIGIGGSLPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGIYASAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPATVSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNMRAKGTPEKVFTVSHIKTPK-QMDEFIEIQSSTGTWYQRWLVRFMTIFKQVWDNALYCVMGPYRMNTLILAVVWFTMALSYYGLTVWFPDMIRYFQDEEYKSKMKVFFGEHVHGATINFTMENQIHQHGKLVNDKFIKMYFKHVLFEDTFFDKCYFEDVTSTDTYFKNCTIESTTFYNTDLYKHKFIDCRFINSTFLEQKEGCHMDFEEDNDFLIYLVSFLGSLSVLPGNIISALLMDRIGRLKMIGGSMLISAVCCFFLFFGNSESAMIGWQCLFCGTSIAAWNALDVITVELYPTNQRATAFGILNGLCKLGAILGNTIFASFVGITKVVPILLAAASLVGGGLVALRLPETREQVLM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG39-1", "uniprot_id": "SV2B_MOUSE", "id": "Q8BG39-1", "name": "Synaptic vesicle glycoprotein 2B", "aln": "-MDDYR---YR----DNYEGYAP--SDGY-YRSNEQNQEEDAQSDVTEGHDEEDEIYEGEYQGIPHPDDVKSKQTKMAPSRADGLGGQADLMAERMEDEEELAHQYETIIDECGHGRFQWTLFFVLGLALMADGVEIFVVSFALPSAEKDMCLSSSKKGMLGLIVYLGMMAGAFILGGLADKLGRKKVLSMSLAINASFASLSSFVQGYGAFLFCRLISGIGIGGSLPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGIYASAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPATVSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNMRAKGTPEKVFTVSHIKTPK-QMDEFIEIQSSTGTWYQRWLVRFMTIFKQVWDNALYCVMGPYRMNTLILAVVWFTMALSYYGLTVWFPDMIRYFQDEEYKSKMKVFFGEHVHGATINFTMENQIHQHGKLVNDKFIKMYFKHVLFEDTFFDKCYFEDVTSTDTYFKNCTIESTTFYNTDLYKHKFINCRFINSTFLEQKEGCHMDFEEDNDFLIYLVSFLGSLSVLPGNIISALLMDRIGRLKMIGGSMLISAVCCFFLFFGNSESAMIGWQCLFCGTSIAAWNALDVITVELYPTNQRATAFGILNGLCKFGAILGNTIFASFVGITKVVPILLAAASLVGGGLIALRLPETREQVLM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L1I2-1", "uniprot_id": "SV2B_HUMAN", "id": "Q7L1I2-1", "name": "Synaptic vesicle glycoprotein 2B", "aln": "-MDDYK---YQ----DNYGGYAP--SDGY-YRGNESNPEEDAQSDVTEGHDEEDEIYEGEYQGIPHPDDVKAKQAKMAPSRMDSLRGQTDLMAERLEDEEQLAHQYETIMDECGHGRFQWILFFVLGLALMADGVEVFVVSFALPSAEKDMCLSSSKKGMLGMIVYLGMMAGAFILGGLADKLGRKRVLSMSLAVNASFASLSSFVQGYGAFLFCRLISGIGIGGALPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGLYASAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPCTVSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNMRAKGTPEKVFTVSNIKTPK-QMDEFIEIQSSTGTWYQRWLVRFKTIFKQVWDNALYCVMGPYRMNTLILAVVWFAMAFSYYGLTVWFPDMIRYFQDEEYKSKMKVFFGEHVYGATINFTMENQIHQHGKLVNDKFTRMYFKHVLFEDTFFDECYFEDVTSTDTYFKNCTIESTIFYNTDLYEHKFINCRFINSTFLEQKEGCHMDLEQDNDFLIYLVSFLGSLSVLPGNIISALLMDRIGRLKMIGGSMLISAVCCFFLFFGNSESAMIGWQCLFCGTSIAAWNALDVITVELYPTNQRATAFGILNGLCKFGAILGNTIFASFVGITKVVPILLAAASLVGGGLIALRLPETREQVLM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WCQ3-1", "uniprot_id": "X1WCQ3_DANRE", "id": "X1WCQ3-1", "name": "", "aln": "MADPYQNNIYHQGDGDSYGTYGQGGQDGYGYQTDYPPQEEDAASDATEGHDEDDQMYEGEYQGIPHPDEVKAARR--------AARAKARTPTDTVSELEELAEQYEDIMEDCGHGKFQWTLFVVLGLALMADSVECFVVALVLPSAEKDMCLSHAEKGMLGLIVFLGMMFGAFIWGGLADKVGRRKCLIIVLAMNCISAFFSSFAQGYGFFLFFRLFSGIGIGGSVPIVYSYFSEFLQMDKRGEHLSWLCMFWMMGGIYASFTAWGIIPRYGWGFSMGTEFQFHSWRVFVLVCALPAIAAFVGLMFMPESPRFLLENAKHDEAWMILKQVHDTNWRAKGQPEKVFTVTQIRTPKTQEDEFIEIQTATGTAFQRWVVRTLTLTKLVIKNVLSLFGRELRLATLLMAIIWFTMAFSYYGLSVWFPDMIKHLQHEEYESKVKVFHREKVEQFHFNFSLENQVHKEGEYINDKFINIEMKSVKFEDSLFVDCFFENVRSTETMFENCTIRSTVFYDTDLYEEKFIDCTMENVTFLHNKKGCHLDYEEDNDVLIYLVSFLGSLAVLPGNIISALFMDKIGRIKIIGGSMLVSAGCTFFLFLSFSQAAIIAWQCLFYGVSVAAWNGIQVITVELYPASKRATAFGFLNAMCKLAAILGSSIFASFIGITKVIPILLSFAALVSGGVLALKLPETREKVLM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *: *: *.* *. .*** *: : **** **.******:*::************:**: : . .:: :: :.: *:**.*** *:::****:*** **.** ******.** ***::.*********** ::*****:**:**** **** ******:**:: * : **:*. * :***.**** *** **:*******::***::******. :********* :*** **:*** **.***:*********:::********:*****. .::*.* *********** .**************** **** *******::*:*** * *******::*** :***:** *: * * .*.* . *: **::*::**:**:*****:*******:::*.***:**:***. *:* :**::***:*:.*: :**** .: :* * ***::* .*:**:* **:* *:****.** **:****:.***:* : * ***.:*:***:* *:***.***********:**********:**:***:*:******:** * ****:. *::*:*.***** *.*:****.::********:.:******:**.:**:.****.:*****:*****:****: *:**.**::**:******:***", "identical_positions": 433, "similar_positions": 160, "identity": "62.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2797", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZIK8-1", "uniprot_id": "D3ZIK8_RAT", "id": "D3ZIK8-1", "name": "", "aln": "-MGPRKKSVKVCVMDSEVPEEMTADEEKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKLKEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDCSFLTLLKKMPDVEQLYGLHPRYLERRRVRGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPENKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMRNCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVLGACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDEFLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHALKLDSFGQFVELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDNDNNAQNNNANIHDNNHHHPDDSDDDNDFRQDLQQG-EAQFAADALNEMEDMVQDDGEVVAESGSGVPAH-QGVLP-VDADEEQAGPSGLQRVVKPTPIAVHDSESDDEEDSLELQEVWIPKNGARRYSEREEKTGDSGQPRETAAVSGKGKTPLRKRYNNSHQMGQAKQFPLEESSCEKGCQVTSEQIKADMKAARDISEKKKTKDVYPSCS----TTAASTVGNSSSPSTASQSPDFVRTVTSGGSSEPSPPEVDVSRQCVCSPGGSEDSEAMEE-GDAESSVCPRCCCLRPQESQRRTSRRSDEERPSTSRACVVNGADGTRSAFSFRTLPQGGSSGPAHDERTNGSGCGATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLSHVPLIPESEIAKTKPCHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICVIHEFSNPPNVRNKVRIRNWMDTIANINQELIKYEFFLEATRTEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKRGVFQRVVAIFIHYCDVNGEPVEDDYI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMI0-1", "uniprot_id": "FBX38_MOUSE", "id": "Q8BMI0-1", "name": "F-box only protein 38", "aln": "-MGPRKKSAKVCVMDSEVAEEMTADEEKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKLKEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDSSFLTLLKKMPDVEQLYGLHPRYLERRRVRGQEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPENKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMRNCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVLGACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDEFLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWISDHSRWMRLVDINLVRCHALKLDSFGQFVELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDNDNNAPNNNANLHDNNHHHPDDSDDDNDFRPDLQAG-EAQFAADALNEMEDMVQEDGELVAESGNGMPAHNREVLP-VDADEEQAGPSGLQRVVKPTPIADHDSESDDEEDSLELQEVWAPKNGTRRYSEREEKTGDSGQSRET-AVSGKGKTPLRKRCNNSHQTGQAKPFPLEESSCEKGCQVTSEQIKADMKAARDVSEKKKSKDVYPSCSSSSSSTAASTAGNASSPSTASQSPDFARTVTSSGSSEPSPPEVDVSRQCVCSPGGSEDSEAMEE-GDAESSVCPRCCCLRPQESQRRTGRCSDEERPSTSRACVVNGADGTRSAFSFRTLPQGGSSGPAHDERTNGSGCGATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLSHVPLISESEVAKTKPCHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRNWMDTIANINQELIKYEFFLEATRTEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLRSLRTAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKRGIFQRVVAIFIHYCDVNGEPVEDDYI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PIJ6-1", "uniprot_id": "FBX38_HUMAN", "id": "Q6PIJ6-1", "name": "F-box only protein 38", "aln": "-MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKLKEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRVRGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPENKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMRNCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVLGACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDEFLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNND-DNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPG-EQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAIIP-VDVDEEQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSREL-SVSGKGKTPLRKRYN-SHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCS----STTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEE-GDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFSFRTLPQGGSSGPAHDERTNGSGSGATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLSHVLLVSESEVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F2P7-1", "uniprot_id": "E7F2P7_DANRE", "id": "E7F2P7-1", "name": "", "aln": "MMSPRRKVTRTHSLGGGTLSSLGHEEPKDYINELSHEVLCHIFRYLPMQDIMCMECLSRKLREAVTLYLRVVKVVDLCASRWWEYMPSGFTDSSFLMLMKKMPDLEQLYGLHPRYLERRRVRGYEAFSIPGVLEALQACPNLIGVETSHLELVEAVWNYMPQVHILGKFRNRNGAFPIPSENKLTIPAAAKIQTLHLVGVNVPEIPCLSMLRHLYLKWVRLTKPQPFKDFLCVNLRTFVMRNCAGPTNSLKYVPLVTGLASARNLEQLELVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVFGACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDEFLLQCNMSHAELVKYGLADVIENPGIITDIGMKAVNEVFTSIKYLVIYNCPHLHNPHNWITDHSRWSRLVDLTLVRCHAIKLESFSQFIELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDNDNNNNNNHQNNNDANIPPNNNDNQVENVPQQNHRGPEAEIPVVEGMVAENIEPEPVLVAANPQEENQSSSQTPNPSLEQDEEQAGPSGVQTSVKKPSVVVSDSDSEDE-----YSPVRTP--AAARSQGQYPETEAQGKSSTAGTPHGKGKTPLRRRGP-----------QPQELSCEKGCQVTSEQIKADMKAATETAER-----------------GAKDRNSGSAPASN----------YSAGS-------------CVCSIRWREDSANQDDQGGAGDMVRTRCTCNRSRSSSENRTR-SGHGLPTGGDNHRAEEMEDRHSNASARTP----SSFEGHNNRTAGHSS------HRG----------PTDEFPRRPITRARSRLSSVPLVCESELPKAKPRTAVKRKRMADKSTSTSDPVTEDDHVQVLSLKSKNLVGITLTNCGITDLVLKECPKMMFVHATRCRVLKHLVVESAPIVNRFDYAQCKKLDMEQVLDQILRMPPERNRIIYMRPMQQIDSLALEKKLFSGPYPYHIAIIHEFSNPPNVRNKVRVRSWMDTIANISQELIKYEFFPEATRTEEDVKKYPSYPWGRDIYTLEGVVDGAPYSMITDFPWLRSLRTAEPNTYARYDFEDDESTTIYAPRRKGQLSADICMETIGEEISERRQTCKGVFQRVVVVFIHYCDVRGEPVEDDYI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.**:* .:. :.. ..: :* ***:*:**************:*************:**********:******.************.*** *:*****:****************** ******************:***********::*.***:*****************.****.** .******************:.******:****************:.********************************:**:******************************:****************************************************************..*::*:*********:******************:.****.**********:***:***** ****:.******:**:**.**:************************************************ *** **: * :* * ::.:: ::. : : * * ::.. *:: : :.*:. . : : * :: *********:* ** ..:. **:*:** . * * .: * . : :* . :. : ********:* :* ******************** : .*: *. ...*: : *.** *.** *** :: *.* . * .** * *.:.*... * *.. *: . .: :. :* * ** ** .*::** * .. :** ..:::****:******** * *: ***:.*:** *:**** *********** ******** ********:*:***********:******:*********** **.***************:*:******************:*****:*:*:**:***********.:***************:*.********.********* ****:***:****.*****:****************:*********:****::*********.:************************** ** :*:*****.:*******.*********", "identical_positions": 803, "similar_positions": 181, "identity": "66.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2799", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99JT9-1", "uniprot_id": "MTND_MOUSE", "id": "Q99JT9-1", "name": "Acireductone dioxygenase", "aln": "--MVQAWYMDESTA-DPRKPHRAQPDRPVSLEQL-RTLGVLYWKLDADKYENDPELEKIRKMRNYSWMDIITICKDTLP---NYEEKIKMFFEEHLHLDEEIRYILEGSGYFDVRDKE--DKWIRISMEKGDMITLPAGIYHRFTLDEKNYVKAMRLFVGEPVWTPYNRP--ADHFDARVQYMSFLEGTA------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q562C9-1", "uniprot_id": "MTND_RAT", "id": "Q562C9-1", "name": "Acireductone dioxygenase", "aln": "--MVQAWYMDESTA-DPRMPHRAQPDRPVGLEQL-RTLGVLYWKLDADKYENDPELEQIRKTRNYSWMDIITICKDSLP---NYEEKIKMFFEEHLHLDEEIRYILEGSGYFDVRDKE--DKWIRISMEKGDMITLPAGIYHRFTLDEKNYVKAMRLFVGEPVWTPYNRP--ADHFDARVQYVKFLEGTA------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BV57-1", "uniprot_id": "MTND_HUMAN", "id": "Q9BV57-1", "name": "Acireductone dioxygenase", "aln": "--MVQAWYMDDAPG-DPRQPHRPDPGRPVGLEQL-RRLGVLYWKLDADKYENDPELEKIRRERNYSWMDIITICKDKLP---NYEEKIKMFYEEHLHLDDEIRYILDGSGYFDVRDKE--DQWIRIFMEKGDMVTLPAGIYHRFTVDEKNYTKAMRLFVGEPVWTAYNRP--ADHFEARGQYVKFLAQTA------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PBX5-1", "uniprot_id": "MTND_DANRE", "id": "Q6PBX5-1", "name": "Acireductone dioxygenase", "aln": "MSVFEAWYMDEESGEDQRLPHKLSPNQPVSVQQL-EHIGVFHWKLNADIYENDPELQKIREEKGYSFMDIITIHPDKLP---DYQNKLKMFYEEHLHLDDEIRYILEGSSYFDVRDEG--DRWIRIAVSKGDLITLPAGIYHRFTVDESNYTKAMRLFVGEPVWKAYNRP--ADDFDIRKEYVNSLGSS-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6AWN0-1", "uniprot_id": "MTND_DROME", "id": "Q6AWN0-1", "name": "Acireductone dioxygenase", "aln": "--MVQVWYMDTEET-DQRLEHHRNPPAYLELDDLYQKTGVEYFKINADEYQSDNTLTELRAKRGYTYDDEITCSEKCLP---DYANKLKAFFTEHLHTDEEIRLILEGSGYFDVRDNE--DNWLRIKVVKGDLIIIPAGIYHRFTLDTNNFIRTRRYFVGEPVWAPHNRP--ADEMDCRKSYIKHQSENFVQFNKV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03677-1", "uniprot_id": "MTND_YEAST", "id": "Q03677-1", "name": "Acireductone dioxygenase", "aln": "--MVKVYIHDNKVDSDYRAPHN--SGTELSLDEL-AKLGVIY-----KYCANEEEVNEIARQREYKNRDVVNICEGSFKSEAEFNEKLATFYQEHLHEDEEIRYCLEGAGYFDVRDASTPENWIRCLVESGDLLILPPGIYHRFTLTTSNHIKALRLFKDEPKWQAINRSNQADSLPVRKDYIALINQY-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:.: * * * *. . : :::* ** : . .: : :: : *. * :. : :: :*: *: **** *:*** *:*:.****** :.*:* : .**:: :*.*******: .*. :: * * .** * . **. ** : * .*: ", "identical_positions": 51, "similar_positions": 52, "identity": "26.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2808", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62487-1", "uniprot_id": "RPB7_HUMAN", "id": "P62487-1", "name": "DNA-directed RNA polymerase II subunit RPB7", "aln": "MFYHISLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKYGFVIAVTTIDNIGA--GVIQPGRGFVLYPVKYKAIVFRPFKGEVVDAVVTQVNKVGLFTEIGPMSCFISRHSIPSEMEFDPNSNPPCYKTMDEDIVIQQDDEIRLKIVGTRVDKNDIFAIGSLMDDYLGLVS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62488-1", "uniprot_id": "RPB7_MOUSE", "id": "P62488-1", "name": "DNA-directed RNA polymerase II subunit RPB7", "aln": "MFYHISLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKYGFVIAVTTIDNIGA--GVIQPGRGFVLYPVKYKAIVFRPFKGEVVDAVVTQVNKVGLFTEIGPMSCFISRHSIPSEMEFDPNSNPPCYKTMDEDIVIQQDDEIRLKIVGTRVDKNDIFAIGSLMDDYLGLVS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62489-1", "uniprot_id": "RPB7_RAT", "id": "P62489-1", "name": "DNA-directed RNA polymerase II subunit RPB7", "aln": "MFYHISLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKYGFVIAVTTIDNIGA--GVIQPGRGFVLYPVKYKAIVFRPFKGEVVDAVVTQVNKVGLFTEIGPMSCFISRHSIPSEMEFDPNSNPPCYKTMDEDIVIQQDDEIRLKIVGTRVDKNDIFAIGSLMDDYLGLVS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7ZW41-1", "uniprot_id": "RPB7_DANRE", "id": "Q7ZW41-1", "name": "DNA-directed RNA polymerase II subunit RPB7", "aln": "MFYHISLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKYGFVIAVTTIDNIGA--GVIQPGRGFVLYPVKYKAIVFRPFKGEVVDAVVTQVNKVGLFTEIGPMSCFISRHSIPSEMEFDPNSNPPCYKTVDEDVVIQQDDEIRLKIVGTRVDKNDIFAIGSLMDDYLGLVS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFB5-1", "uniprot_id": "Q9VFB5_DROME", "id": "Q9VFB5-1", "name": "DNA-directed RNA polymerase II subunit RPB7", "aln": "MFYHISLEQEILLHPRYFGPQLLETVKQKLYSEVEGTCTGKYGFVIAVTTIDQIGS--GVIQPGQGFVVYPVKYKAIVFRPFKGEVLDAVVKQINKVGMFAEIGPLSCFISHHSIPADMQFCPNGNPPCYKSKDEDVVISGEDKIRLKIVGTRVDATGIFAIGTLMDDYLGLVSN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34087-1", "uniprot_id": "RPB7_YEAST", "id": "P34087-1", "name": "DNA-directed RNA polymerase II subunit RPB7", "aln": "MFFIKDLSLNITLHPSFFGPRMKQYLKTKLLEEVEGSCTGKFGYILCVLDYDNIDIQRGRILPTDGSAEFNVKYRAVVFKPFKGEVVDGTVVSCSQHGFEVQVGPMKVFVTKHLMPQDLTFNAGSNPPSYQSSED--VITIKSRIRVKIEGCISQVSSIHAIGSIKEDYLGAI--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: .*. :* *** :***.: : :* ** ****:****:*:::.* *:*. * * * * . : ***:*:**:******:*..* . .: *: .::**:. *:::* :* :: * ...***.*:: :: ** ...**:** * : ..*.***:: :**** : ", "identical_positions": 69, "similar_positions": 60, "identity": "39.43%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2810", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJK8-1", "uniprot_id": "ACBD6_RAT", "id": "Q5RJK8-1", "name": "Acyl-CoA-binding domain-containing protein 6", "aln": "MAT--PFLPAGATTG--------DSGGELSSGDDSGD---LESFQTPEAEATR-----SLAELFEKAAAHVQGLVQVASREQLLYLYARYKQVKVGNCNIPKPNFFDFEGKQKWEAWKALGDSSPSQAMQEYIAAVKKLDPGWNPQVSEKKGKEGSSGFGGPVVSSLYHEETIREEDKNIFDYCRENNIDHITKAIKSKTVDVNMTDEEGRALLHWACDRGHKELVKVLLQCEAGINCQDNEGQTALHYAAACEFSDIVELLLQSGADPTLRDQDGCLPEEVTGCKAVSLVLQLHRAGKA----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D061-1", "uniprot_id": "ACBD6_MOUSE", "id": "Q9D061-1", "name": "Acyl-CoA-binding domain-containing protein 6", "aln": "MAT--PFLPSGATTG--------DSGGELSSGDDSGD---MESFQTPEAEGTR-----SLAELFEKAAAHVQGLVQVASREQLLYLYARFKQVKVGNCNTPKPNFFDFEGKQKWEAWKALGDSSPSQAMQEYIAAVKKLDPGWNPQVSEKKGKEGSSGFGGPVVSSLYHEETIREEDKNIFDYCRENNIDHIAKAIKSKAADVNMTDEEGRALLHWACDRGHKELVKVLLQYEAGINCQDNEGQTALHYAAACEFLDIVELLLQSGADPTLRDQDGCLPEEVTGCKAVSLLLQRHRASKA----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BR61-1", "uniprot_id": "ACBD6_HUMAN", "id": "Q9BR61-1", "name": "Acyl-CoA-binding domain-containing protein 6", "aln": "MAS--SFLPAGAITG--------DSGGELSSGDDSGE---VEFPHSPEIEETS-----CLAELFEKAAAHLQGLIQVASREQLLYLYARYKQVKVGNCNTPKPSFFDFEGKQKWEAWKALGDSSPSQAMQEYIAVVKKLDPGWNPQIPEKKGKEANTGFGGPVISSLYHEETIREEDKNIFDYCRENNIDHITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEGQTALHYASACEFLDIVELLLQSGADPTLRDQDGCLPEEVTGCKTVSLVLQRHTTGKA----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4V8X4-1", "uniprot_id": "ACBD6_DANRE", "id": "Q4V8X4-1", "name": "Acyl-CoA-binding domain-containing protein 6", "aln": "MASRSPSSSPDSATGSGTDPARPDTGEPLGGGSDSDSDFGLGKFDCSAGDASARLEGADLENEFESAADRVRDLVQTASREQLLYLYARFKQVKVGKCNTSKPGFFDFEGQRKWSAWKQLGDMSAEQAMQEYVTCVHALDPEGSQKSSERRGGEKRTGFGGPAVSSLYQEEKIREEDKNIFDYCRENNIEHVSKAISSKTVDVNTRDEEGRALLHWACDRGHKDLVSLLLQNNADINSQDDEGQTALHYASACEFAEIVELLLKAGADPSIKDQEGSLPEEVTESSAISSLLRQYTAPKG----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRG6-1", "uniprot_id": "Q9VRG6_DROME", "id": "Q9VRG6-1", "name": "Acyl-CoA-binding domain-containing protein 6", "aln": "-----------------------------MSDSDTDT----------------------VDELFHLATEHVAKQSNSIGSADLLIFYGYYKQATNGPCKEQSPGLLQLQAKSKWQAWRNLGTMSQSAARQAYVQKLQELQPNWRSR--------RNPGWVVHSIESVPLEDQRLDSEKTLFDHVKENNLDRLRELLQPS--DLVKLDEHGMALIHWATDRNAVEIIQFLVRSGASVNQRDAEQQTPLHYAASCGHLEALQCLLELHASLELRDSDGQTCYDVADDEQICQVLQTERERLAGSAS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ...*:. : : *. *: :: : . :** :*. :**.. * *: .*.:::::.: **.**: ** * . * * *: :: *:* : .*: :.*: *: :.:*.:**: :***:::: : :... *: **.* **:*** **. ::: .*:: *.:* :* * **.****::* . : :: **: *. ::*.:* :*: . :. :*: . ", "identical_positions": 62, "similar_positions": 93, "identity": "20.39%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2816", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H5Y7-1", "uniprot_id": "SLIK6_HUMAN", "id": "Q9H5Y7-1", "name": "SLIT and NTRK-like protein 6", "aln": "-------MKLWIHLFYSSLLACISLHSQTPVLSSRGSCDSLCNCEEKDGTMLINCEAKGIKMVSEISVPPSRPFQLSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTHLDLRGNQLQTLPYVGFLEHIGRILDLQLEDNKWACNCDLLQLKTWLENMPPQSIIGDVVCNSPPFFKGSILSRLKKESICPTPPVYEEHEDPSGSLHLAATSSINDSRMSTKTTSILKLPTKAPGLIPYITKPSTQLPGPYCPIPCNCKVLSPSGLLIHCQERNIESLSDLRPPPQNPRKLILAGNIIHSLMKSDLVEYFTLEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIKEILPGTFNPMPKLKVLYLNNNLLQVLPPHIFSGVPLTKVNLKTNQFTHLPVSNILDDLDLLTQIDLEDNPWDCSCDLVGLQQWIQKLSKNTVTDDILCTSPGHLDKKELKALNSEILCPGLVNNPSMPTQTSYLMVTTPATTTNTADTILRSLTDAVPLSVLILGLLIMFITIVFCAAGIVVLVLHRRRR-YKKKQVDEQMRDNSPVHLQYSMYGHKTTHHTTERPSASLYEQHMVSPMVHVYRSPSFGPKHLEEEEERNEKEGSDAKHLQRSLLEQENHSPLTGSNMKYKTTNQS-TEFLSFQDASSLYRNILEKERELQQLGITEYLRKNIAQLQPDMEAHYPGAHEELKLMETLMYSRPRKVLVEQTKNEYFELKANLHAEPDYLEVLEQQT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IS19-1", "uniprot_id": "A0A0R4IS19_DANRE", "id": "A0A0R4IS19-1", "name": "", "aln": "MHRRNKKKMLARIVFICSFFAGASFGDTESKASYGGACKSLCTCEEKDGVLYVNCEERNISRISDVKVPSDVPFHLNLYKNDLVELLAEDVEAFKNAITLHLGANSIQELEPGVFSALGSLKKLHINSNFLVMLKEDTFQGLVNLEYLQADTNFIRVVEPGAFSKLIRLKVLILNDNSIDFLPSNIFRFVPLTHLDLRGNKLQTLPYVGFLEHIGRIMELLLEDNDWVCNCEILHLKVWIENMRAQSSIGEVVCNKPENLKGTSLARVKRDSLCPS-HADINLEEPLQSQDMVVTP-------STKVVQIPNAKDDA--------KKPTPANGPETVCGSVCSCYPSAGFLMHCENRGIQRISDIGILEQSPTKLFLSGNMIQRLYKYDFVTYDTLDVLNLSNNQIDYIDNETFLSLSNLKKLQLNGNRIERISATMFLGLHNLEYLYLEYNVIKEIEAGSFNPLTNLRLLFLNNNLLNTLPAQIFRNVPLVMLNLRKNVFTHLPVSNALEQLSFLEQIYLEDNPWDCTCDLVSLKQWVERLTRDTVVGTILCKTPQKLAAVDVRNLKHDILCPGLVTYKSIGKHTEDVFLVTPAPQGGTS-SFFGSLK-EVPLSVLILCLLILFLTVIFCSAGIVVFVLHRRRRQAKKKQAEEQPRESSPIHLHYSMYGQKTTHHVTERQGPVMYDEPSRSPIVQVCRNPSYCSQHKEYELGDYDSE--KAKHICHSLLDKGNES---LPNVKFRAVSDYPAEFVGLGDTSSLYKSILERERELQQLSLTEYLRKNISQLQPAVDMQVPNHHKELKLMETLVYTRPRKVMVEQTKNEYFELKANLHAEPDYLEVLEHQTTFN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :* .*::* *: . . * *:*.***.******.: :*** :.*. :*::.**.. **:*.* :*.*. * ::*...:.***::*** *.* ::* *.*..** **:**** * * :******:** ***:****.*** *:**.***** **********:*: **.****************:****************::* ****.*.***::*:**.*:*** .** **:****.* :**: *:*:*::*:**: . : *:* * .:..*. ***...* : .* * .* ** . *. ..:*:*:**::*.*: :**: *.* **:*:**:*: * * *:* * **::*:*.**:*: ::: :*:.*:.*:** ****:: ::* ****************.**** .*:***:.:*::*:******:.**.:** .***. :**:.* ******** *::*.:* ** ********:****.*:**:::*:::**.. ***.:* :* ::: *: :*******. *: .:*. :::.***. .*: ::: **. ******** ***:*:*::**:*****:******* ****.:** *:.**:**:*****:*****.*** .. :*:: **:*:* *.**: .:* * * :.* .***: :***:: *.* .*:*:::..: :**:.: *:****:.***:*******.:********:**** :: : *. *:********:*:*****:**************************:** ", "identical_positions": 449, "similar_positions": 243, "identity": "52.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2818", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70352-1", "uniprot_id": "CD82_RAT", "id": "O70352-1", "name": "CD82 antigen", "aln": "-MGAGCVKVTKYFLFLFNLLFFILGAVILGFGVWILADKSSFISVLQTSSS----------SLQVGAYVFIGVGAITMLMGFLGCIGAVNEVRCLLGLYFVFLLLILIAQVTVEVLFYFNANKLKQEMGNTVMDIIQNYSVNASSSRE-EAWDYVQAQVKCCGWVSPSNWTRNPVLKNSTKTTYPCSCEKTKEEDNQLIVKKGFCES-DNSTASENSPEDWPVHPEGCMEKAQAWLQENFGILLGVCAGVAVIELLGLFLSICLCRYIHSEDYSKVPKY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40237-1", "uniprot_id": "CD82_MOUSE", "id": "P40237-1", "name": "CD82 antigen", "aln": "-MGAGCVKVTKYFLFLFNLLFFILGAVILGFGVWILADKNSFISVLQTSSS----------SLQVGAYVFIGVGAITIVMGFLGCIGAVNEVRCLLGLYFVFLLLILIAQVTVGVLFYFNADKLKKEMGNTVMDIIRNYTANATSSRE-EAWDYVQAQVKCCGWVSHYNWTENEELMGFTKTTYPCSCEKIKEEDNQLIVKKGFCEA-DNSTVSENNPEDWPVNTEGCMEKAQAWLQENFGILLGVCAGVAVIELLGLFLSICLCRYIHSEDYSKVPKY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27701-1", "uniprot_id": "CD82_HUMAN", "id": "P27701-1", "name": "CD82 antigen", "aln": "-MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSS----------SLRMGAYVFIGVGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGIVTELIRDYNSSREDSLQ-DAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKGEEDNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIELLGMVLSICLCRHVHSEDYSKVPKY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q6P4-1", "uniprot_id": "F1Q6P4_DANRE", "id": "F1Q6P4-1", "name": "Tetraspanin", "aln": "-MGKGCITATKYFLFLFNFIFFIFGATIMGFGLWILLDNQSLIAVLQESSV----------ILKVVSYILIGVGSFSMLLGFLGCLGAIYEIRCLLGLYFTCLLLILLAQVAVSILIYFQRDLLKTEADKIVSQVVANYP-GQNKTAE-QAWDYLQRTMQCCGWNGRMDWDENHIIKNNTVPLYPCSCHNYSIQAP-IVPDNGFCQA---------SSSDWPIYQTGCLEHVGSWLFTNYGIILGICLGVAVIELLGMILSMGLCKSVHQEDYTKVPKY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3E5-1", "uniprot_id": "Q9V3E5_DROME", "id": "Q9V3E5-1", "name": "Tetraspanin", "aln": "MVFDCGVWCAKYLLCIFNFIFFVLGTIIFGVGLWLAVDKHSLIALLKLVESERIEQFTQPQAIEQLAYVLLVIGAVMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESKNFLQTTITSYSLGENVDATSLMWNQLMGNFGCCGINDYHDFDASPAWVNGKGNRTIPDACCILKDVAKLVPRDEDCTT--------NPSDSNSFYKKGCYEVFTEWLIRQRELVI-VAIAVGIVHLVLIILAFALCKAFAKYNDMRL---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :**:* :**::**::*: *:*.*:*: *: *:*::*: . :. :*::: :*:. :.:.*** :**: * ****. * . *:*:*:*::.. * * . :: * : : .* . *: : . *** . :: . . .. : : . * : ... .. ** * ** : ::: : .*.::.*: :.*:: **: . . : :: ", "identical_positions": 52, "similar_positions": 91, "identity": "18.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2826", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P16371-1", "uniprot_id": "GROU_DROME", "id": "P16371-1", "name": "Protein groucho", "aln": "MYP-----SPVRHP--------------AAGGPPPQGPIKFTIADTLERIKEEFNFLQAQYHSIKLECEKLSNEKTEMQRHYVM-----------------------YYEMSYGLNVEMHKQTEIAKRLNTLINQLLPFLQADHQQQVLQAVERAKQVTMQELNLIIGH------------QQQHGIQQLLQQIHAQQVPGGPPQP-------MGALNPFGALGATMG----LPHGPQGLLNKPPEHHRPDIKPTGLEGPAAAEERLRNSVSPADREKYRTRSPLDIENDSKRRKDEK-LQEDEG---EKSDQDLVVDVAN----EMESHSPRPNGEHVSMEVRD----RESLNG-ERLEKPSSSGIKQERPPSRSGSS-------------SSRSTPSLKTKDMEKPGTPGAKARTPTPNAAAPAPGVNPKQMMPQGPP--------PAGYPG-----APYQR--PADPYQRPPSDPAYGRPPPMPYD-PHAHVRTNGIP-HPSALTGGKPAYSFHMNGEGSLQPVPFPPDALVGVG-IPRHARQINTLSHGEVVCAVTISNPTKYVYTGGKGCVKVWDIS--QPGNKNPVSQLDCLQRDNYIRSVKLLPDGRTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVRSWDLREGRQLQQHDFSSQIFSLGYCPTGDWLAVGMENSHVEVLHASKPDKYQLHLHES-CVLSLRFAACGKWFVSTGKDNLLNAWRTPYGASIFQSKETSSVLSCDISTDDKYIVTGSGDKKATVYEVIY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0AB32TBS6-1", "uniprot_id": "A0AB32TBS6_DANRE", "id": "A0AB32TBS6-1", "name": "", "aln": "MFPQNRPPAPLQPPPGSSASAAAAAAAAAAAASGSTQPLKLTYPETLDRIKEEFQFLQTQYHSLKLECEKLATEKTEIQRHYVM-----------------------YYEMSYGLNIEMHKQTEIAKRLNVICAQLIPFLSQEHQQQVVQAMERAKQVTMGELNASIGVRGLPPLPPTQQLQAQHLSQHAAQGLPMAPHPSGLPHPGLALGGGSGLLALSGALGAQLASKDERAHLEAVAAAAAAEHHRDWPRGRLPALPMIPIDREPGPSSLSNGDKGRSSD--YLSNGKKRKADEKEFMTDYGSDAEKSDDNLVVDEDPSSPRSVQSYSSRENGLDKLPPSRKEPLPQASPTS-LASSSSAASPSRSKEPPPREKSSTPGMKPGTPMSQESSTPGPSVPPQFRPVPGKPGVDPLALGLRNPLAVQGAYPPGAFGLPPPGVNGELAGAAGYGAGLHLVSPQMNGSAAAAAAAAAAAAGYGRSPVVGYESPHPHMRVPGLPGSLQSAATGKPAYSFHVSADGQMQPVPFPPDALLGPG-IPRHARQIHTLSHGEVVCAVTISTSTRHVYTGGKGCVKVWDIS--QPGSKSPMAQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLSIWDLATPTPRIKAELTSSAPACYALAISPDNKVCFSCCSDGNIVVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRCWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVSKPDKYQLHLHES-CVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGSSIFQSKESSSVLSCDISPDDQFIVTGSGDKKATVYEVIY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04725-1", "uniprot_id": "TLE2_HUMAN", "id": "Q04725-1", "name": "Transducin-like enhancer protein 2", "aln": "MYP------QGRHP----------------TPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVM-----------------------YYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNSLIGQQ-------------LQPLSHHAPPVPLTPRPAGLVGGS-----ATGLLALSGALAAQAQ---LAAAVKEDRAGVEAEGSRVERAPSRSASPSPPE-------SLVEEERPSGPG----GGGKQ-RADEKEPSGPYESDEDKSDYNLVVDEDQPSEPPSPATTPCGKVPICIPARRDLVDSPASLASSLGSPLPRAKELILNDLPASTPASKS---CDSSPPQDASTPGPSSASHLCQLAAKPAPSTDSVALRSPLTLSSPFTTSFSLGSHSTLNGDLSVPSSYVS-------------LHLSPQVSSSVVYGRSP-VMAFESHPHLRGSSVSSSLPSIPGGKPAYSFHVSADGQMQPVPFPSDALVGAG-IPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVG--QPGAKTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHLHES-CVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVTGSGDKKATVYEVVY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WVB2-1", "uniprot_id": "TLE2_MOUSE", "id": "Q9WVB2-1", "name": "Transducin-like enhancer protein 2", "aln": "MYP------QGRHP----------------TPLQSGQPFKFSVLEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMAAPHQCPQGGTSYPHWPRLSPLQYYEMSYGLNIEMHKQAEIVKRLSAICAQMVPFLTQEHQQQVLQAVDRAKQVTVGELNSLLGQQN-----------QLQPLS-HAPPVPLTPRPAGLVGAG-----ATGLLALSGALAAQAQ---LVAAVKEDRVGVDAEGSRVDRAASRSSSPSPPE-------SLVEEDHPSSRG----GSGKQQRAEDKDLSGPYDSEEDKSDYNLVVDEDQPSEPPSPVTTPCGKAPLCIPARRDLTDSPASLASSLGSPLPRSKDIALNDLPTGTPASRS---CGTSPPQDSSTPGPSSASHLCQLAAQPAAPTDSIALRSPLTLSSPFTSSFSLGSHSTLNGDLSMPGSYVG-------------LHLSPQVSSSVVYGRSPLQMAFESHPHLRGSSVS--LPGIPVAKPAYSFHVSADGQMQPVPFPSDALVGTG-IPRHARQLHTLAHGEVVCAVTISSSTQHVYTGGKGCVKVWDVG--QPGSKTPVAQLDCLNRDNYIRSCKLLPDGQSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQAMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSHVEVLHVRKPEKYQLRLHES-CVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVTGSGDKKATVYEVVY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1W2PR48-1", "uniprot_id": "TLE7_HUMAN", "id": "A0A1W2PR48-1", "name": "Transducin-like enhancer protein 7", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MSGEKEEASLRMFG---------------------------------------------------------------------------------------AYGEPEERRDVLESSGVS---------------------------------------------------------------------------------------------------------------------------------------SQPEPQVQQQLGSLLGVPWQPPGPPIQHSPADQETSTVTQQQWHLQG----------------------------LGRSELQAAGLPDAQPGEAAESSPSFLLGSEVGQPYSSSSPSEEVLSLLRAIP------PIPDEVVVRQKRAPQGSWKVGTLFHGKRVYAVAISGSTHHVYTCGSGYIRVWDESALHAGEKAPRAQLDLQHPQDRVVTCKLFPDERSLITGGASQAVTLWDLAP-TPQVRAQLTSTGPTCYSLAVSSDAHICLACFH-GFVEIWDLQNQILIRKHEVPVYGSRCVDIT--GNIFWTGGEDTILYSWDLRSYQRLHQHNLQNEILSITHDPGEEWVLAGLRTSDIVFLHTRRNEQFKALMKKYTRHHSLKFASCGSYFVT-AIDTRLSGLEAPSLQKLFQIEESSGILCCDVSSDNQYLVMGSSSS-ATIYQLLY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::: :: . .* * * . *. : . * . . . . : . * . ..: : . . .: . *: *:* :.:: *: : :: ** **: * **:** .*::*** *.* ::*** . :.* * * :*** : :: : : **:** ::**.** :. :::****. **:::*:***:.*:**:**:*.* ::*::* * : :***:*: ::*:.: . *: *:**: *. :**** *. : .****. ::*:**:: .:*:*: : * :*: .*:..*.: .**. : :::: ::: **:** ** :**: . *. *.. .:* .:** :*:*.:*.**:* :::::* **... **:*:::*", "identical_positions": 118, "similar_positions": 156, "identity": "14.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2829", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08047-1", "uniprot_id": "SP1_HUMAN", "id": "P08047-1", "name": "Transcription factor Sp1", "aln": "MSDQDHSMDEMTAVVKIEKGVGGNNGGNGNGGG-AFSQARSSSTGSSSSTGGGG-QESQPSPLALLAATCSRIESPNENSNNSQGPSQSGGTGELDLTATQLSQGANGWQIISSSSGATPTSKEQSGSSTNGSNGSESSKNRTVSGGQYVVAAAPNLQNQQVLTGLPGVMPNIQYQVIPQFQTVDGQQLQFAATGAQVQQDGSGQIQIIPGANQQIITNRGSGGNIIAAMPNLLQQAVPLQGLANNVLSGQTQYVTNVPVALNGNITLLPVNSVSAATLTPSSQAVTISSSGSQESGSQPVTSGTTISSASLVSSQASSSSFFTNANSYSTTTTTSNMGIMNFTTSGSSGTNSQGQTPQRVSGLQGSDALNIQQNQTSGGSLQAGQQKEGEQNQQTQQQQILIQPQLVQGGQALQALQAAPLSGQTFTTQAISQETLQNLQLQAVPNSGPIIIRTPTVGPNGQVSWQTLQLQNLQVQNPQAQTITLAPMQGVSLGQTSSSNTTLTPIASAASIPAGTVTVNAAQLSSMPGLQTINLSALGTSGIQVHPIQGLPLAIANAPGDHGAQLGLHGAGGDGIHDDTAGGEEGENSPDAQPQAGRRTRREACTCPYCKDSEGRGSGDPGKKKQHICHIQGCGKVYGKTSHLRAHLRWHTGERPFMCTWSYCGKRFTRSDELQRHKRTHTGEKKFACPECPKRFMRSDHLSKHIKTHQNKKGGPGVALSVGTLPLDSGAGSEGSGTATPSALITTNMVAMEAICPEGIARLANSGINVMQVADLQSINISG-NGF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O89090-1", "uniprot_id": "SP1_MOUSE", "id": "O89090-1", "name": "Transcription factor Sp1", "aln": "MSDQDHSMDEVTAVVKIEKDVGGNNGGSGNGGGAAFSQTRSSSTGSSSSSGGGGGQESQPSPLALLAATCSRIESPNENSNNSQGPSQSGGTGELDLTATQLSQGANGWQIISSSSGATPTSKEQSGNSTNGSNGSESSKNRTVSGGQYVVAATPNLQNQQVLTGLPGVMPNIQYQVIPQFQTVDGQQLQFAATGAQVQQDGSGQIQIIPGANQQIIPNRGSGGNIIAAMPNLLQQAVPLQGLANNVLSGQTQYVTNVPVALNGNITLLPVNSVSAATLTPSSQAGTISSSGSQESSSQPVTSGTAISSASLVSSQASSSSFFTNANSYSTTTTTSNMGIMNFTSSGSSGTSSQGQTPQRVGGLQGSDSLNIQQNQTSGGSLQGSQQKEGEQSQQTQQQQILIQPQLVQGGQALQALQAAPLSGQTFTTQAISQETLQNLQLQAVQNSGPIIIRTPTVGPNGQVSWQTLQLQNLQVQNPQAQTITLAPMQGVSLGQTSSSNTTLTPIASAASIPAGTVTVNAAQLSSMPGLQTINLSALGTSGIQVHQLPGLPLAIANTPGDHGTQLGLHGSGGDGIHDETAGGE-GENSSDLQPQAGRRTRREACTCPYCKDSEGRASGDPGKKKQHICHIQGCGKVYGKTSHLRAHLRWHTGERPFMCNWSYCGKRFTRSDELQRHKRTHTGEKKFACPECPKRFMRSDHLSKHIKTHQNKKGGPGVALSVGTLPLDSGAGSE--GTATPSALITTNMVAMEAICPEGIARLANSGINVMQVTELQSINISG-NGF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QW97-1", "uniprot_id": "F1QW97_DANRE", "id": "F1QW97-1", "name": "", "aln": "MSDLKK-REKLAPSHRMSDPQKSSMADSE----PGFPQKSSSSSAQDSQ---------QPSPLALLAATCSRIDENGAAEPQTRQDSQ-----------LELPQGTNGWHISPAGT-QTPTS-APAAVPTAPSEERSRAATATIQP-QFLMPAQS----QQLLTALPGVMPNIQYQVIPQFQTVDGQQLQLQAA-----QDMSGQLLVSSPGGQQLR---AAGSGNILTVPGLFQQAIPLQNLS-AVLPNQTQFLANVP--LNANITLLPVG-------------------------PGPVGG----DTHTAVAAPPQGPEFCSTA---SSTRATAAVGIATLAQSRAPAAS----------------------------------------DGQKGQPQMLLQG--VQQG-------AVSAPGPVFTTQTLSQDGVQNVQIQTIASGSPILIR--TLGADGQVSWQTLQLQ-----SPGAQ-ITLAPTG--------------------ASGP--------VQLS---GLQTINLNTLGSGGLQMQPIQ-MPVTIASAPG---------EAAADALEDSAVLEENAESSP--NTASSRRTRREACTCPYCKDGEGR---DPSKKKQHICHIPGCGKVYGKTSHLRAHLRWHTGERPFVCSWSFCGKRFTRSDELQRHKRTHTGEKKFSCTECPKRFMRSDHLSKHIKTHLNKK----VCVSACSDPVTPAADAD------PQTLLT-----VDSLSADSFTRLP-GGISVMQVTDLQSIGLSGSNGF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** .: ::::. ::.. .. ... .*.* ***:...*. ***************:. . . ::: ** :*.**:***:* .:.: **** :. .* *: . : . *:. *:::.* . **:**.*************************: *: ** ***: : . ..**: .:*.. * ::*.*:***:***.*: **..***:::*** **.*******. . ** . .: : *:: .....* :.* *:* :*: :** .:: * :..:. . *. * *:*:* ** * *.. .* .****::**: :**:*:*:: ...**:** *:*.:*********** .* ** ***** ** * .*** *******.:**:.*:*:: : :*::**.:** :..*.:.*.:. * .*.*. :. :.***************.*** **.********* *************************:*.**:************************:*.******************* *** *.:*. : *: ..*.:: *.:*:* ::::..:.::**. .**.****::****.:** ***", "identical_positions": 318, "similar_positions": 197, "identity": "40.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2831", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35348-1", "uniprot_id": "ADA1A_HUMAN", "id": "P35348-1", "name": "Alpha-1A adrenergic receptor", "aln": "-------MVFLSGNAS------DSSNCTQPPA-PVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSD-SEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTLHPP----SQAVEGQHKD-MVRIPVGSRETFYRISKTDGVCEWKFFSSMPRGSARITVSKDQSSCTTARVRSKSFLQVCCCVGPSTPSLD--KNHQVPTIKVHTISLSENGEEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97718-1", "uniprot_id": "ADA1A_MOUSE", "id": "P97718-1", "name": "Alpha-1A adrenergic receptor", "aln": "-------MVLLSENAS------EGSNCTHPPA-QVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGVRALLCVWALSLVISIGPLFGWRQQAPEDETICQINEEPGYVLFSALGSFYVPLTIILVMYCRVYVVAKRESRGLKSGLKTDKSD-SEQVTLRIHRKNVPAEGSGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPNFKPPETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTLHPP----SQAVEGQHRG-MVRIPVGSGETFYKISKTDGVREWKFFSSMPQGSARITMPKDQSACTTARVRSKSFLQVCCCVGSSTPRPE--ENHQVPTIKIHTISLGENGEEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FG90-1", "uniprot_id": "E7FG90_DANRE", "id": "E7FG90-1", "name": "Alpha-1A adrenergic receptor", "aln": "MPGRLEQMVPFKDNMTPESFPENCSNCSQVLVPELNVMKAVALGVVLAIFIVFGVLGNILVILSVACHRNLRTVTHYFIVNLAVADLLLSSTVLPFSTVFEMLGRWIFGRPFCDVWAAMDVLCCTASIMSLCVISVDRYIGVSYPLQYPSIVTERRALLALIALWVLSITISIGPLFGWKEPAPDDESICKITEEPGYAIFSALGSFYLPLVVILSMYCRVYVVARRETRGLISGQKTEKSDHAETVTLRIHRGNMTVSED--EALRNRTHFALRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVLPIGSIFPTYRPSDTVFKITFWLGYFNSCINPIIYPCSSQEFKKAFLSVLGARCLRKRSTPSHTL-YQSHSPRHGQSQILGLSSRDNPSRLSPSSSIALSRSPSSRDGRDWQAPSRTSSVGTTGVSTGVSVGAKMAGMCGKNLLRTCCCVRADSPQPEPPAQNSLPVIKIHQLSLCEDGDAV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** :. * : : ***:: . :*: **: ***:*. :*:*****************:*::****:***********:*******::**:** * *** **::***:**********.**:**:**********:**:***:**.: **:.:*.**:.*********:: **:**:**:*.*****.:********:**.:** *********:**:*** ** **:*** :* ******* * .. . : :.:***::********************************:****:** ::*.:*****.*****:******************** .** :** ::.:..*:* * *.* ** : . :. *:. .* :: : ..: . :*: * . .: . . . ... * : .*.:*:.**** ..:* : ::.:*.**:* :** *:*: *", "identical_positions": 270, "similar_positions": 125, "identity": "55.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2838", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5EBA1-1", "uniprot_id": "SUV3_RAT", "id": "Q5EBA1-1", "name": "ATP-dependent RNA helicase SUPV3L1, mitochondrial", "aln": "---------MSLPRCALLWARLPAGRGAGPRAAPCSALRALVGSFPGASGRVPCLA-ASSSASGGSKAPNTSLFVPLTVKPQGPSADGDVGAELTRPLDKNEVKKILDKFYKRQEIQKLSADYGLDARLFHQAFISFRNYIMQSHSLDVDIHIVLNDICFSAAHVDDLFPFFLR--------------------HAKQIFPVLECKDDLRQIS--DLRRPPNWYPEARAIQRKIIFHSGPTNSGKTYHAIQRYLSATSGVYCGPLKLLAHEIFEKSNAAGVPCDLVTGEERL-TVEPEGKQATHVSCTVEMCNVATPYEVAVIDEIQMIRDPARGWAWTRALLGLCAEEVHLCGESAAIDLVTELLYTTGEEVEVQKYERLTPISVLDRALES-LDNLRPGDCIVCFSKNDIYSVSRQIEIRG-LESAVIYGSLPPGTKLAQARKFNDPNDPCKILVATDAIGMGLNLSIRRIIFYSLIKPSINEKGEKELEPITTSQALQIAGRAGRFSSHFKEG-----EVTTMHRDDLALLKEILNRPVDPIQAAGLHPTAEQIEMFAYHLPE--TTLSNLIDIFVDFAQVDG-QYFVCNMDDFKFSAELIQHIPLSLRVRYVFCTAPINKKQPFVCSSLLQFARQYSRNEPLTFAWLRRYIKWPLL--PPKNIKDLMDLEAVHDVFDLYLWLSYRFIDMFPDSSFVRSLQKELDVIIQEGVHNITKLIKISESHKLLNLE--PSGSQSRLPGASKSPARRTRGTKTG-NKAAEPPSPSDKELPLASRLVQQGLLTADMLKQLQKEWLTQRP-------EQGKEK----------VGTRRKKKDPNSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80YD1-1", "uniprot_id": "SUV3_MOUSE", "id": "Q80YD1-1", "name": "ATP-dependent RNA helicase SUPV3L1, mitochondrial", "aln": "---------MSLPRCTLLWARLPAGRGAGPRAAPCSALRALVGSFPGASGRVPCLA-ASSSASGGSKAPNTSLFVPLTVKPQGPSADGDVGAELTRPLDKNEVKKILDKFYKRQEIQKLSADYGLDARLFHQAFISFRNYIMQSHSLDVDIHIVLNDICFSAAHVDDLFPFFLR--------------------HAKQIFPVLECKDDLRKIS--DLRIPPNWYPEARARQRKIIFHSGPTNSGKTYHAIQRYLSATSGVYCGPLKLLAHEIFEKSNAAGVPCDLVTGEERL-TVEPEGKQATHVSCTVEMCNVATPYEVAVIDEIQMIRDPARGWAWTRALLGLCAEEVHLCGESAAINLVSELLYTTGEEVEVQKYERLTPISVLDHALES-LDNLQPGDCIVCFSKNDIYSVSRQIEIRG-LESAVIYGSLPPGTKLAQARKFNDPNDPCKILVATDAIGMGLNLSIRRIIFYSLIKPSINEKGEKELEPITTSQALQIAGRAGRFSSHFKEG-----QVTTMHRDDLALLKDILNRPVDPIQAAGLHPTAEQIEMFAYHLPE--TTLSNLIDIFVDFAQVDG-QYFVCNMDDFKFSAELIQHIPLSLRVRYVFCTAPINKKQPFVCSSLLQFARQYSRNEPLTFAWLRRYIKWPLL--PPKNIKDLMDLEAVHDVFDLYLWLSYRFIDMFPDSSLVRSLQKELDAIIQEGVHNITKLIKISESRKLLNLESLPSGDQSRLSGASKSPARRTRGTKSAGNKATEPLSPSDKELPLASRLVQQGLLTADMLRQLQKEWLTQQP-------EHSREK----------VGTRRKKKDPDSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IYB8-1", "uniprot_id": "SUV3_HUMAN", "id": "Q8IYB8-1", "name": "ATP-dependent RNA helicase SUPV3L1, mitochondrial", "aln": "---------MSFSR-ALLWARLPAGRQAGHRAAICSALRPHFGPFPGVLGQVSVLATASSSASGGSKIPNTSLFVPLTVKPQGPSADGDVGAELTRPLDKNEVKKVLDKFYKRKEIQKLGADYGLDARLFHQAFISFRNYIMQSHSLDVDIHIVLNDICFGAAHADDLFPFFLR--------------------HAKQIFPVLDCKDDLRKIS--DLRIPPNWYPDARAMQRKIIFHSGPTNSGKTYHAIQKYFSAKSGVYCGPLKLLAHEIFEKSNAAGVPCDLVTGEERV-TVQPNGKQASHVSCTVEMCSVTTPYEVAVIDEIQMIRDPARGWAWTRALLGLCAEEVHLCGEPAAIDLVMELMYTTGEEVEVRDYKRLTPISVLDHALES-LDNLRPGDCIVCFSKNDIYSVSRQIEIRG-LESAVIYGSLPPGTKLAQAKKFNDPNDPCKILVATDAIGMGLNLSIRRIIFYSLIKPSINEKGERELEPITTSQALQIAGRAGRFSSRFKEG-----EVTTMNHEDLSLLKEILKRPVDPIRAAGLHPTAEQIEMFAYHLPD--ATLSNLIDIFVDFSQVDG-QYFVCNMDDFKFSAELIQHIPLSLRVRYVFCTAPINKKQPFVCSSLLQFARQYSRNEPLTFAWLRRYIKWPLL--PPKNIKDLMDLEAVHDVLDLYLWLSYRFMDMFPDASLIRDLQKELDGIIQDGVHNITKLIKMSETHKLLNLEGFPSGSQSRLSGTLKSQARRTRGTKALGSKATEPPSPDAGELSLASRLVQQGLLTPDMLKQLEKEWMTQQT-------EHNKEKTESGTHP---KGTRRKKKEPDSD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4IG62-1", "uniprot_id": "SUV3_DANRE", "id": "A4IG62-1", "name": "ATP-dependent RNA helicase SUPV3L1, mitochondrial", "aln": "---------MSVNRCIYLLSRSHIRYRVCASTN-LSTVSTLSTTQHSTRRTFDKLS-TRHSSSGSSRPLDTSLFIPLPVKTD-EDAEGSVGAELTKPLDKNELLKVLNRFYKRKEMQKLASDQGLDARLFHQAFVSFRKYVLEMNSLNADLHIILNDICCGAGHIDDIFPYFMR--------------------HAKQIFPMLDCIDDLRKIS--DLRVPANWYPEARAIQRKIVFHAGPTNSGKTYHAIKRYLEAKSGVYCGPLKLLAHEIYEKSNAAGVPCDLVTGEERI-FVDPEGKPSGHIASTIEMCSVTTPYEVAVIDEIQMIKDPARGWAWTRALLGLCAEEIHVCGEAAAVDFITELMFTTGEEVEVHNYKRLTPFSISNHAVES-LDNLKPGDCIVCFSKNDIYSISRQIEIRG-LECAVIYGSLPPGTKLAQAKKFNDPDDPCKILVATDAIGMGLNLSIRRIIFNSLVKHSLNEKGEKEVDTISTSQALQIAGRAGRFSSVFKEG-----EVTTMHRDDLPVLKEILGKPVDPIATAGLHPTAEQIEMFAYHLPQ--ATLSNLIDIFVSLSQVDG-LYFVCNIDDFKFLADMIQHIPLNLRSRYVFCTAPINKKQPFVCTSFLKFARQFSRDEPLTFNWVCRQVNWPLS--PPKNIKDLVHLEAVHDVLDLYLWLSYRFMDMFPDSNQIREIQKELDENIQIGVRNITRLIRAIDSQ--------PTDTESNSSSTVPESETSQRKGRVLRSQNQRKELP--RKSSLSSRLLRDGLLTKELLSQLQKEWAREQN-------EDNSIP----------VNNGKRKKK----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN03-1", "uniprot_id": "SUV3_DROME", "id": "Q9VN03-1", "name": "ATP-dependent RNA helicase SUV3 homolog, mitochondrial", "aln": "--------MQNCRRCISLTGLLRMTLYLRPSFSIDLSLRRLHRAAFLFSRKKPETN-------------LSTLFKPVQVHAYVDSED--VGSELSGKLEKAELLKILNKFTQRREIKSLCNENGLDDYLQQQAFGSFRRFCIEAENLPVDLHITFSDITQGAGHIDDIFPYFLR--------------------HAKTVFPHLDCMDDLKKIS--DLRQPANWYSNARAITRKIVFHAGPTNSGKTYHAMERYLSAKTGVYCGPLKLLATEVYNKANERGTPCDLVTGEERK-FGISESLPANHVACTVEMTSVNTPYEVAVIDEIQQIRDPQRGWAWTRAFLGLIADEVHVCGEPGALDLLQKICETTGETVEVRLYDRLTELTVENTALGS-LDNIVPGDCIVCFSKHDIYTVSREIEARG-KEVAVIYGGLPPGTKLAQAAKFNDPANSCKVMVATDAIGMGLNLSIRRIIFYSLIKPSMNERGEREIDTISVSSALQIAGRAGRFRTQWEHG-----YVTAFKSEDLQTLQRILARTPEPIKQAGLHPTADQIELYAYHLPS--SSLSNLMDIFVNLCTVDDSLYFMCNIEDFKFLAEMIQHVALPLRARYVFCCAPINRKMPFVCSMFLKVARQYSRNEPITFDFIKKNCGWPFK--LPKTILDLVHLEAVFDVMDLYLWLSYRFMDLFPEAAYVRDAQKELDEIIQQGVFQITRLLKN---------------TEASQDGETSNYAIRR------ITHVKEPRLPSLSRGRLTERLLAQGLLTPGMLSELRKEWDAQQLGKSNSQSNENSEPVVNSDDEDNYSGIGRKTRKKRRK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32580-1", "uniprot_id": "SUV3_YEAST", "id": "P32580-1", "name": "ATP-dependent RNA helicase SUV3, mitochondrial", "aln": "MALVKYSTVFFPLRSLRLFVSIKKAYYHSEPHSIDLFHDKDWIVKRPKFLNLPKNEHSKLDIFQFNFNKSESNNVYLQDSSFKDNLDKAMQFIYNDKLSSLDAKQVPIKNLAWLKLRDYIYQQLKDPKLQAKTYVPSVSEIIHPSSPGNLISLLINCNKISNLVWKSVLKYSLSNNITTLDKFIHVLQQTFDHVYEQEILPMMTNTDDTDGAHNVDITNPAEWFPEARKIRRHIIMHIGPTNSGKTYRALQKLKSVDRGYYAGPLRLLAREVYDRFHAEKIRCNLLTGEEVIRDLDDRGNSAGLTSGTVEMVPINQKFDVVVLDEIQMMSDGDRGWAWTNALLGVVSKEVHLCGEKSVLPLVKSIVKMTGDKLTINEYERLGKLSVEEKPIKDGIKGLRKGDCVVAFSKKKILDLKLKIEKDTNLKVAVIYGSLPPETRVQQAALFN--NGEYDIMVASDAIGMGLNLSIDRVVFTTNMKYNG-----EELMEMTSSQIKQIGGRAGRFKSRSASGGVPQGFITSFESKVLKSVRKAIEAPVEYLKTAVTWPTDEICAQLMTQFPPGTPTSVLLQTISDELEKSSDNLFTLSDLKSKLKVIGLFEHMEDIPFFDKLKLSNAPVKDMPMVTKAFTKFCETIAKRHTRGLLSYRLPFNLLDYNCIPNESYSLEVYESLYNIITLYFWLSNRYPNYFIDMESAKDLKYFCEMIIFEKLDRLKK-----------------------------------------NPYAHKPFGSTRGHLSSSRRRLRT--------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : : . . : : . *.. : :: : :::. : * * ::: . :. . : : :. . ..:: : : : : ::* : ** *: *.:*:.:** *:*::* *********:*::: .. * *.***:*** *:::: : *:*:**** .. : : *:** : ::*.*:**** : * ******.*:**: :.*:*:*** ..: :: .: **: : :. *.** ::: : .: . :..: ***:*.***:.* :. :** : *****.*** *:: ** ** . .::**:*********** *::* : :* . .*: :: *. **.****** : * :*::. . * :: : . : : * ** : ::* .: * * .: .. : :.::.. :::*: : . :. *:* . : :... :: .. : *: .* *::.::: **:*** *: : * : :. : : * : .:.: . . . : * : ", "identical_positions": 143, "similar_positions": 207, "identity": "17.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2843", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7ESE9-1", "uniprot_id": "F7ESE9_RAT", "id": "F7ESE9-1", "name": "", "aln": "----------MGTPGVSAGALFLSSASAPPRKRAAGEAGEAGVAKSKQRVLDEEEYIEVPGLQTVIQRDFFPDVEKLQAQKEYLEAEENGDLERMRQIAIKFGSALGKISREPPPP---YVTPATFETPE--VHPGSGVLGSKPRPQGRDPEDAGEAGEEE--EKEPLPSLDVFLSRYTSEDNASFQEIMEVAKEKSHARHAWLYQAEEEFEKRQKDNLELPSAEHQAIES-SQAGVETWKYKAKNSLMYYPEGVPDEE----QLFKKPRQIVHKNTRFLRDPFSQALSRSQLQQAAALNAQHKQGKVGPDGKELIPQESPRVGGFGFVATPSPAPGMNESPLMTWGEVENTPLRVEGSESPYVDRTPGPTFKILEPGRRERLGLKMANEAAAKNRAKKQEALRRVTENLAS--LTPKGLSP-AMSPALQRLVSRTASKYTDRALRASYTPSPAR--------STHLKTPAGGPQTPTSTPAPGSATRTPLTQDPASITDNLLQLP-ARRKASDFF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70279-1", "uniprot_id": "ESS2_MOUSE", "id": "O70279-1", "name": "Splicing factor ESS-2 homolog", "aln": "----------MGTPGTSAGALFLSSASAPSRKRAAGEAGEAGVARSRQRVLDEEEYIEG--LQTVIQRDFFPDVEKLQAQKEYLEAEENGDLERMRQIAIKFGSALGKISREPPPP---YVTPATFETPE--VHPGSAVLGNKPRPQGRDLDD-GEAGEEE--EKEPLPSLDVFLSQYTSEDNASFQEIMEVAKEKSHARHAWLYQAEEEFEKRQKDNLELPSAEHQAIES-SQAGVETWKYKAKNSLMYYPEGVPDEE----QLFKKPRQIVHKNTRFLRDPFSQALSRSQLQQAAALNAQHKQGKVGPDGKELIPQESPRVGGFGFVATPSPAPGVNESPLMTWGEVENTPLRVEGSESPYVDRTPGPTFKILEPGRRERLGLKMANEAAAKNRAKKQEALRRVTENLAS--LTPKGLSP-AMSPALQRLVSRTASKYTDRALRASYTPSPAR--------SSHLKTPAGGPQTPTSTPAPGSATRTPLTQDPASITDNLLQLP-ARRKASDFF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96DF8-1", "uniprot_id": "ESS2_HUMAN", "id": "Q96DF8-1", "name": "Splicing factor ESS-2 homolog", "aln": "----------METPGASASSLLLPAASRPPRKR---EAGEAGAATSKQRVLDEEEYIEG--LQTVIQRDFFPDVEKLQAQKEYLEAEENGDLERMRQIAIKFGSALGKMSREPPPP---YVTPATFETPE--VHAGTGVVGNKPRPRGRGLED-GEAGEEE--EKEPLPSLDVFLSRYTSEDNASFQEIMEVAKERSRARHAWLYQAEEEFEKRQKDNLELPSAEHQAIES-SQASVETWKYKAKNSLMYYPEGVPDEE----QLFKKPRQVVHKNTRFLRDPFSQALSRCQLQQAAALNAQHKQGKVGPDGKELIPQESPRVGGFGFVATPSPAPGVNESPMMTWGEVENTPLRVEGSETPYVDRTPGPAFKILEPGRRERLGLKMANEAAAKNRAKKQEALRRVTENLAS--LTPKGLSP-AMSPALQRLVSRTASKYTDRALRASYTPSPAR--------STHLKTPASGLQTPTSTPAPGSATRTPLTQDPASITDNLLQLP-ARRKASDFF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QAX0-1", "uniprot_id": "F1QAX0_DANRE", "id": "F1QAX0-1", "name": "", "aln": "----------MAESREKAVCLRSDVTTVAVRNP----VEES--KKPKRKILDEEQYIES--LEKIIQRDFFPDVSKLQAQKDYLEAEENGDLERMREIAIKYGSAMAKYTPRTYVP---HVTPSTFETPD--GRSAS---PSSSQSKSRAAREDGKDGEKA--SEKDLPSLDRFLSKNTSEDNASFEQIMELAEDKDKLRHAWLYEAENEYKERHEQNLALPSSEKQALEC-TKAGLETWQYKAKNSLMYYPEGEKDD-----TLFKKPREVLYKNTRFEDDPFCKALNKSQIQQAAALNAQFKQGKVGPDGKELLPHESPKVNGYGYEGAPSPAPGVAESPLMTWGEIESTPFRLEGSDTPLVERSHGPSFKIPEPGRRERLGLKMANEAAAKNRAKKQEALRKVTENLAS--LTPKGLSPAALSPALQRLVNRSSSKYTDKALRASYTPSPAHR-------SLGAKTPSGGLTTLTPTPTK---TRTPASQDPASITDNLLQLP-KRRKAQDYF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O44424-1", "uniprot_id": "ESS2_DROME", "id": "O44424-1", "name": "Splicing factor ESS-2 homolog", "aln": "MSATTRTPATPGTPGTPGSLAMEVARVQNSALAEFKKPTAMVRHKNKPKILTEEKYIEE--MSKIIQRDFFPDLERLRAQNDYLDAESRRDFVQMAEIRERYSLGRISGTGRSTSRRNNAMSPATFETPVSQAKCSNTPLPNSRATDTPFSTDGSEKSDAEGRDTTAKLSLDAFLQKYTSEDNQSFQEIIETAEAKLRQKYAVLYNHEKLSAEQLQRALMLPSIETQFEEPDPLRKIETWNYTNMNSIMYVPDGVEYTEEERVQLAERKQSIQHNATRLPDEAKHREMDTKKLNDEVPQNGAGG------------ATATPKVRGFDLLRSPSPRPGEAFSPIMTWGEIDGTPFRLDGGDTPLRP-TQGPSFRINENSRRENIAIALAERVSERMRNQKQMALDTARRNIGSPLIRTNMERLASMSPAAQLLATGKLGIRGTPRLRHTPSPMSGRKRKVTPGVVRSTNTPILGEPKPKQQAKISTPAKNVTIDTGSTLTDDLLKIPTKRRTAADFF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : ::* **:*** :..:********:.:*:**::**:**.. *: :* :* ::. . . : .. ::*:***** : .. .. . : .: .: . *** **.: ***** **::*:* *: : : ::* **: *: :: : * *** * * * . :***:*. **:** *:* * :: :.: :: **: :. : :. :::: .. *. . :*:* *:. :*** ** **:*****::.**:*::*.::* : **:*:* * .***.:.: :*:..: : * :** ** . .*:.* : .: ::*** * *.. . . ** : :* ..: :** * . . . ::. : :::**:**::* **.* *:*", "identical_positions": 127, "similar_positions": 151, "identity": "24.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2845", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54748-1", "uniprot_id": "STK3_RAT", "id": "O54748-1", "name": "Serine/threonine-protein kinase 3", "aln": "-----------MEQPPAPKS----KLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDVQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKSPEQRATATQLLQHPFIKNAKPVSILRELITEGMEIKAKRHE----------EQQRELEDEEENSDED------------------------ELDSHTMVKTSSE-------GVGTMR--------ATSTMSEGAQTMIEHNS---TMLESDLGTMVINSEDEE------EEDGTMKRNATSPQVQRPSFMDYFDK----------------------QDFKNKSHENCDQSMREPCPMSNNVFPDNWR----------------------------------------------------VPQ------------------------------DGDFDFLKNLSLEELQMRLKALDPMMEREIEELHQRYSAKRQPILDAMDAKKRRQQNF-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JI10-1", "uniprot_id": "STK3_MOUSE", "id": "Q9JI10-1", "name": "Serine/threonine-protein kinase 3", "aln": "-----------MEQPPASKS----KLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKSPEQRATATQLLQHPFIKNAKPVSILRDLIAEAMEIKAKRHE----------EQQRELEEEEENSDED------------------------ELDSHTMVKTSSE-------SVGTMR--------ATSTMSEGAQTMIEHNS---TMLESDLGTMVINSEEEEEEEEEEEEDGTMKRNATSPQVQRPSFMDYFDK----------------------QDFKNKSHENCDQSMREPGPMSNSVFPDNWR----------------------------------------------------VPQ------------------------------DGDFDFLKNLSLEELQMRLKALDPMMEREIEELHQRYSAKRQPILDAMDAKKRRQQNF-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13188-1", "uniprot_id": "STK3_HUMAN", "id": "Q13188-1", "name": "Serine/threonine-protein kinase 3", "aln": "-----------MEQPPAPKS----KLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKNAKPVSILRDLITEAMEIKAKRHE----------EQQRELEEEEENSDED------------------------ELDSHTMVKTSVE-------SVGTMR--------ATSTMSEGAQTMIEHNS---TMLESDLGTMVINSEDEE------EEDGTMKRNATSPQVQRPSFMDYFDK----------------------QDFKNKSHENCNQNMHEPFPMSKNVFPDNWK----------------------------------------------------VPQ------------------------------DGDFDFLKNLSLEELQMRLKALDPMMEREIEELRQRYTAKRQPILDAMDAKKRRQQNF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZUQ3-1", "uniprot_id": "STK3_DANRE", "id": "Q7ZUQ3-1", "name": "Serine/threonine-protein kinase 3", "aln": "-----------MEHS-VPKN----KLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATVLKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPEHWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIVGAKPVSILRDLITEAMDMKAKRQQ----------EQQRELEEDDENSEEEV-----------------------EVDSHTMVKSGSE-------SAGTMR--------ATGTMSDGAQTMIEHGS---TMLESNLGTMVINSDDEEEE----EDLGSMRRNPTSQQIQRPSFMDYFDK----------------------QDS-NKAQEGFNHNQQDPCLISKTAFPDNWK----------------------------------------------------VPQ------------------------------DGDFDFLKNLDFEELQMRLTALDPMMEREIEELRQRYTAKRQPILDAMDAKKRRQQNF-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8T0S6-1", "uniprot_id": "HIPPO_DROME", "id": "Q8T0S6-1", "name": "Serine/threonine-protein kinase hippo", "aln": "MSEPEVTSVVDMKSPNISSSCSFFKLKKLSEESLLQPPEKVFDIMYKLGEGSYGSVYKAVHKESSSIVAIKLVPVESDLHEIIKEISIMQQCDSPYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIEEIGYDCVADIWSLGITALEMAEGKPPYGEIHPMRAIFMIPQKPPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELLEHEFIRNAKHRSILKPMLEETCAIREQQRANRSFGGVLAASQAKSLATQENGMQQHITDNAFMEDPGTLVPEKFGEYQQSSASDATMIAHAEQGVDEGTLGPGGLRNLSKAAAPAAASSAASPLDMPAVDSGTMVELESNLGTMVINSDSDD------STTAKNNDDQKPRNRYRPQFLEHFDRKNAGDGRGDEKPIATEYSPAAAEQQQQQQQQQQQQQQDEQHLASGANDLNNWEHNMEMQFQQISAINQYGLQQHQQQQQVLMAYPLMNEQLIALNNQPNLLLSNAAPMGQQGIPAAAPAQPPPAYQNQHMHTQSHAYVEGEFEFLKFLTFDDLNQRLCNIDHEMELEIEQLNKKYNAKRQPIVDAMNAKRKRQQNINNNLIKI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . ... *******:** : **:***:: **********:**:****..:**** ******::******************:*******: **** ************:***:*** ******:*..**:** ***: *********.********:**********************************:****:***********::*********.:*********** :***:**:*: ** :* ***.*****.*::*****:**:* ** .** ***: :: * :: ::: .* :.* :::. ::. . .. **: . : . * :* *:.: : .. * .* . ***:********:.:: . .. . : .. : **.*:::**: :: :: :: ::. : * :**. .* :*:*:*** * :::*: ** :* ** ***:*.::*.******:***:**::****: ", "identical_positions": 283, "similar_positions": 129, "identity": "41.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2854", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1PJK7-1", "uniprot_id": "A0A8M1PJK7_DANRE", "id": "A0A8M1PJK7-1", "name": "", "aln": "------MPLNPVISKLSGKLVVLASASPRRLEILSNAG--LRFEVVPSWFKETLDKSLFKH-PCEYAVETAKQKALEVAQRMPFK-------------------------------------HLKTPDIVIGADTVVT-VDGLILEKPTDKQDAYRMLSRLSGKEHS---VFTGVAIVICRDKNSSVTDYKVVDFYEETKVKFA-ELSEEMLWEYINSGEPMDKAGGYGIQALGG-MLVEYVRGDFLNVVGFPLNHFCKQLGSIFNSP-PASPAHKIKRD----CDEAWTLVNKTTNGDVELLENVKDDSLTSVQEQNVMGLEFAKCNRQ-----DVPHSIISLLDGFKVSKTLFTASKLKVFDVLNTPGGLTLEEVAGQINASLLGTERLLEAAVSLGLLERVRQEEISVYRNTEQASRFLVTDSPVSLHGYILHCNDMVWPLFSHLESAVREGTSQHERAFGKKKEDVFQDVYYSKDEVKIRFMDAMHSIARVTGKDLATAFDLSCYKTACDIGGCTGAMAYEFTKAHPELSVTIFDLPQVIEMRRHFQPK-ENDERVSFVAGDFFKDDLPKADLYILARVLHDWSDEKLHVLLSKLSKMWTPGCGLLVSEILLDEERRRPSRALLQALSM---TEGKQRSTAEYSALLDKHGFTLKHVKHTDNLLDAMLFVKEEQNDKRTLLGCSSASIETAELE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O95671-1", "uniprot_id": "ASML_HUMAN", "id": "O95671-1", "name": "Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein", "aln": "------MVLCPVIGKLLHKRVVLASASPRRQEILSNAG--LRFEVVPSKFKEKLDKASFAT-PYGYAMETAKQKALEVANRLYQK-------------------------------------DLRAPDVVIGADTIVT-VGGLILEKPVDKQDAYRMLSRLSGREHS---VFTGVAIVHCSSKD-HQLDTRVSEFYEETKVKFS-ELSEELLWEYVHSGEPMDKAGGYGIQALGG-MLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSDVEGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKGLLTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQG----YSNTETANVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQSPETRLRFMRAMHGMTKLTACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTVFDLPDIIELAAHFQPPGPQAVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLSRVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFHQVQVVHLGGVLDAILATKVAP--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AKB0-1", "uniprot_id": "A0A8I6AKB0_RAT", "id": "A0A8I6AKB0-1", "name": "", "aln": "------MALKPLAPLLRGYHVVLASASPRRREILDLAG--VVFDVIPSHFSEVPPPEHLLR-PQDLVIANAKGKALDVGMRLSQVREAPVESRLGFCEDDGGVSGCSVLRVGLLVRWRSFLADPETQHLIIGADTIVA-MEGQIMGKPCDREDALRMLTRLNGREHS---VITGVAIILTGGAG-TRDAEVVVVFHEETLVTFS-KLSDELVQEHVEGGEPWDKAGGYGLQARGGAIMAEAVRGDPLNAAGLPLNRLCRELGRRLLPSGPGQEVESQT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86BM0-1", "uniprot_id": "Q86BM0_DROME", "id": "Q86BM0-1", "name": "", "aln": "-------MLAPIKHLLGNYRIVLASGSPRRQELVKMLG--LNAELCPSTFEENLNLEDFKE-FSDYIEATALGKAEEVYSRLRST-------------------------------------GDSKNLIVIAADTMVT-LGKEIYGKPKDPADAIRMLTNLSGTSNR---VFTGVVLKHANGIR---------KFTDTADVYFG-DLLPEQIQSYVDSGDPLDKAGAYGVQGPAG-ALIHRIDGDFYCVMGLPLHRLCCELNKLFLEDLSS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99210-1", "uniprot_id": "NTPPA_YEAST", "id": "Q99210-1", "name": "dTTP/UTP pyrophosphatase", "aln": "MSGNSQLPPDVIGFICSKYDIILASTSPRRYEILHDIMGITDLKTMVSTFEENLDKMNYSTDPIGYVCDTSWHKAQNIIEILTDYEDENPN-------------------------------EIDKPKLIICADTIIIDKSGRIYEKPKTKEVQKKFLMKFCYEDDEPVNVVTAVTLIKWYGRE----NFELVPFRDETKVYFDNKIPLRILEEYVESGDGLEVGGGFKIQGQGA-ILIEKIEGDYYNVVGLPLNKTFKGLYAEANSI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::*** **** *:: . * *.* .: ** :: : ::* ***:: * ** ::* .: .. *.*.*.: . * : : * * .: . : .::..*: : .*.: :*. .. : . : ** . *:**:: * ", "identical_positions": 36, "similar_positions": 54, "identity": "5.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2855", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQJ4-1", "uniprot_id": "ZN384_RAT", "id": "Q9EQJ4-1", "name": "Zinc finger protein 384", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MEESHFNSNPYFWPSIPTVSGQIENTMFINKMKDQLLPEKG--CGLAPPHYPTLLTVPASVSLSSGISMDTESKSEQLTPHSQASVTQN-ITVVPVPSTGLMTAGVSCSQRWRREGSQSRGPGLVITSPSGSLVTTASSAQTFPISTPMIVSALPPGSQALQVVPDLSKKVASTLTEEGGGGGGGGGTVAPPKPPRGRKKKRMLESGLPEMNDPYVLAPGDDDDHQKDGKTYRCRMCSLTFYSKSEMQIHSKSHTETKPHKCPHCSKTFANSSYLAQHIRIHSGAKPYSCN---------------------------------------FCEKSFRQLSHLQQHTRIHSKMHTETIKPHKCPHCSKTFANTSYLAQHLRIHSGAKPYNCSYCQKAFRQLSHLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHRRQHNKDKPFKCHNCHRAYTDAASLEAHLSTHT-VKHAKVYTCTICSRAYTSETYLMKHMRKHNPPDLQQQVQAAAAAAAVAQAQAQAQAQAQAQAQA--------------------------------------------QAQAQAQAQAQA------SQASQQQQQQQPPPPQPPHFQSPG-----------------------------------------------------------------------------------------------AAPQGGGGGDSNQNPPPQCSFDLTPYKPAEHHKDICLTVTTSTIQVEHLASS------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q1A5-1", "uniprot_id": "E9Q1A5_MOUSE", "id": "E9Q1A5-1", "name": "Zinc finger protein 384", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MEESHFNSNPYFWPSIPTVSGQIENTMFINKMKDQLLPEKG--CGLAPPHYPTLLTVPASVSLSSGISMDTESKSEQLTPHSQASVTQN-ITVVPVPSTGLMTAGVSCSQRWRREGSQSRGPGLVITSPSGSLVTTASAAQTFPISAPMIVSALPPGSQALQVVPDLSKKVASTLTEEGGGGGGGGGTVAPPKPPRGRKKKRMLESGLPEMNDPYVLAPGDDDDHQKDGKTYRCRMCSLTFYSKSEMQIHSKSHTETKPHKCPHCSKTFANSSYLAQHIRIHSGAKPYSCN---------------------------------------FCEKSFRQLSHLQQHTRIHSKMHTETIKPHKCPHCSKTFANTSYLAQHLRIHSGAKPYNCSYCQKAFRQLSHLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHRRQHNKDKPFKCHNCHRAYTDAASLEAHLSTHT-VKHAKVYTCTICSRAYTSETYLMKHMRKHNPPDLQQQVQAAAAAAAVAQAQAQAQAQAQAQAQA--------------------------------------------QAQAQAQAQAQAQAQAQASQASQQQQQQQPPP-QPPHFQSPG-----------------------------------------------------------------------------------------------AAPQGGGGGDSNPNPPPQCSFDLTPYKPAEHHKDICLTVTTSTIQVEHLASS------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TF68-1", "uniprot_id": "ZN384_HUMAN", "id": "Q8TF68-1", "name": "Zinc finger protein 384", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MEESHFNSNPYFWPSIPTVSGQIENTMFINKMKDQLLPEKG--CGLAPPHYPTLLTVPASVSLPSGISMDTESKSDQLTPHSQASVTQN-ITVVPVPSTGLMTAGVSCSQRWRREGSQSRGPGLVITSPSGSLVTTASSAQTFPISAPMIVSALPPGSQALQVVPDLSKKVASTLTEEGGGGGGGGGSVAP-KPPRGRKKKRMLESGLPEMNDPYVLSPEDDDDHQKDGKTYRCRMCSLTFYSKSEMQIHSKSHTETKPHKCPHCSKTFANSSYLAQHIRIHSGAKPYSCN---------------------------------------FCEKSFRQLSHLQQHTRIHSKMHTETIKPHKCPHCSKTFANTSYLAQHLRIHSGAKPYNCSYCQKAFRQLSHLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHRRQHNKDKPFKCHNCHRAYTDAASLEVHLSTHT-VKHAKVYTCTICSRAYTSETYLMKHMRKHNPPDLQQQVQAAAAAAAVAQAQAQAQAQAQAQAQA--------------------------------------------QAQAQASQASQQ-------QQQQQQQQQQQQQQPPPHFQSPG-----------------------------------------------------------------------------------------------AAPQGGGGGDSNPNPPPQCSFDLTPYKTAEHHKDICLTVTTSTIQVEHLASS------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ATC2-1", "uniprot_id": "A0A8M3ATC2_DANRE", "id": "A0A8M3ATC2-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MHFRCFKDTAGVMEDSHFSSS-YFWS---PVQGQIENAVFLNKVKEQLGHDKSPTYSHGPAHYP-----PTAVVAVAGGPMEAPTSRTLKQEHVQPSHSSHSITVVPVPPSGIMTAAGLVTLVSPVSSAQS----LIPGHPSMITVQTDKKNDSLPCSP--VIIPLPSKR---------GRKKKETLPLVG--------------SPTGTDPLILGLSGQHLSTHPYSLSPEEGHAGKEGSKTYRCRMCGLTFCSKSDMQLHSKSHTEVKAHQCPHCSKSFANTSYLAQHIRIHSGAKPYTCS---------------------------------------YCQKAFRQLSHLQQHTRNHTES-----KPHKCPHCTKSFANSSYLAQHVRIHTGVKPYTCNYCEKTFRQLSHLQQHHRIHTGDRPYKCTHMGCEKSFTQLSNLQSHRRQHNKDKPYKCHHCNRGYVDAAGLDIHLSTHT-VKHAKLYSCGLCHRTYTSETYLMKHMQKHAP----------------DMLPSPPGSNQHSHSPG--------------------------------------------RAGGSGSEGDGQ---------SRIERSD--------VFVQPI-----------------------------------------------------------------------------------------------SVPCVYDMNQYKPVPAADVQYKTVSVSDISPHKDLCITVEASAIQANHLNS-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDZ3-1", "uniprot_id": "SQZ_DROME", "id": "Q9VDZ3-1", "name": "Zinc finger protein squeeze", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAELPTAPN------------------------------------GVPSGDYLHRSIDQLRSLGHLTTAQLVHDYKPFN------------------------ISEFR-QNVAERLDYSLKNGLVQHQQQMVMEQQ--------------------------PHPDQQQQQHLHHPQQQQHPPQLKVSYSAPNSPPTPHEQQEQKYDPNRSPPR----QQMSSASGSGSNGSSPEEESRRGDG---------------------------------------------------------------------------------DQAKPYKCGSCSKSFANSSYLSQHTRIHLGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHAGCPKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEMTLLEHIPKHKDSKHLKTHICNLCGKSYTQETYLQKHLQKHAEKAEKQ---------QHRHTAQVAAHQQHVPASG------------IGLNLQRQAMNDVNAAYWAKMGADSAAASLAEAIQQQLPQAGGQPYGNFASLQQQHQQQQQELLHHQRLADTPGHSHSP------HEEAAGEDLVLRQSTPQHHLQQQQQQ-------QQQQQAQQQQQAQHQPSPGPGNSAFTP-------------------LSATVAPPPHLQQHRGPPGSAAAYLYQQN-------AAAAAAAFPTQLISLHQIRNYAHQPGAAGLIAGDHLALGLSAVNAAKEKAQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VI93-1", "uniprot_id": "RN_DROME", "id": "Q9VI93-1", "name": "Zinc finger protein rotund", "aln": "MIMHGTWYKGPQLAHHPHSNPHNSSHGHSDYHQFRSYPSFVVTPYHDGHVQGPATPTPCTAPPTPCNGPVPVSVPVSIPVCHTGGQGSPVIVESSFAIAAAAAAAAAAVAVGGSSATPLLPSPPIKIEQVFGEPSSLGAVVEDYALGLDCPVEHTFRKPHNNNGYSWSTGNNNEVVSHSSNGHTNNHPTTPPTPPNEASATQATSVSAINLNQAQPASQTRSNFGSSIKSPPSEPDAVTAATCKSQENNSGQNPTPNSLSDHNPAHNLNSNSTAAAVAAAAAAAAAANMPIGGVQGQNPTQGLVHWMSAVMAEHMTGQTHHDPGAVGMHYMWNGNVDHAKDISDYNLWPPTPRSHQHASEHHPMSLKQEYEAKMNDHHHNNLQKGHFLDDNRLEHHAVTGQGGLGLGASNGVGGGGGGASVVGNSSLGASSHHAVAAAHHHNQAVAAASAAALLVVPQPINASKMGGPGGVSSVAGGHATGGGSGRKYQCKMCPQIFSSKADLQLHTQIHMREAKPYKCTQCSKAFANSSYLSQHTRIHLGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHPGCQKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEPSLLEHIPKHKESKHLKTHICQYCGKSYTQETYLTKHMQKHAERTDKRPPIVPGSAAAIAAAAAAAAGGSANPANGPPPPPNPAQHQRNNLGLPPVSIAPSDNGYWPKVSPDSAAAANAMEVMHQQQQQQQQQQ---QQQQQQQQQQQQQAHHHHPQHGVPPQQHVPPQQQQQQQQQQQHHHPQQQPPPQHSMEAHYAQPTAPNGSQSNGHGAELQPHHRMPDPVREDIASTPSAVGPYDAASITKTTSNSAFTPINSMPPHLNSLSHHPMAQRPYLYDAISFPNKNVNQNNANAFPNQLISLHQIRNYAHQP--AGLMAGEHLLG--VSVGPGKDKG-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: . ... : : : : : * . . : . : : .. .. :: . . **:** *:*:***:***:** *** * *** *. *:: * ******** * ****:**** * ** *:*:******** * *:.***:**: * : : * * *:..*. ** * : * * ::**.**** **::** . : . . .: ::.: * : * . :. . :. . *. .:: . ", "identical_positions": 85, "similar_positions": 76, "identity": "8.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2856", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GBP8-1", "uniprot_id": "A0A8I6GBP8_RAT", "id": "A0A8I6GBP8-1", "name": "Myomesin-1", "aln": "MSLPFYQRSHQHYDLSYRNKDLHTTMSHYQQEKKRSAVYTHGSTAYSSRSSAAHRQESEALRQASAASYQQQASKAYSLGTSSSQHYQGSEVSRKTASSYDYGYSHGLTDSSLLLEDYSSRLSPQTKRAKRSLLSGEETGNLSGNYMVPIYSGRQVHISGIRDSEEERIKEAAAYIAQRTLLESEEAIMASKQSTASKQSTASKQSIASKQSTASKQSTASKQSTAS------KQATSTFQQEETFERKSRNISIREKAEELSLRKTLEETQAYHGKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSVAGWPEPRLTWYKNQVPINVHANPEKYIIESRYGMHTLEISKCDFEDTAQYRASAMNVQGEVSAYASVVVKRYKGELDDSLLRGGVS-MPLSFAVTPYGYASKFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHVQPEVQWYRNGAPVSPSKWVQPHWSGDRATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVVSLDANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDTWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKTGIGLPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPTEGVIPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCDVGTENWQRVNTELPVKSPRFALFDLVEGKSYRFRVRCSNSAGVGEPSESTEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIESSVVGSGQWEPCNNNPVKGSRFTCHGLTTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVWPQLSDTPGGLTDSGGAMSGASPPTSQKDALPSSKPNKPSPPSSPSNRGQKEVSKVNGSVQEELSPPSMEVASKEQSKSGPPEKKKDPVAVPSPPYDITCLESFRDSMVLGWKQPDKTGGAEITGYYVNYREVVGGVPGKWREANIKAVSDAAYKISELKENTVYQFQVSAMNIAGLGAPSAVSECFKCEEWTIAVPGPPHSLKLSEVRKNSLVLQWKPPVYSGRTPVTGYFVDLKEASAKDDQWRGLNEAAIPNKYLRVQGLKEGISYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDQMTPKSEFVWSKDYVPSEDSPRLEVESKGNKTKMVFKDLGPDDLGTYSCDVTDTDGIASSYLIDEEEMKRLLALSQEHKFPTVPTKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQIQDGKATGHSTLVLIGDVYKKLQKEAEFQRQEWIRKQGPHFAEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDG---------ICTLLIT-------------------EFSKKDAGFYEVILKDDRGKDKSRLKLVDEAFQDLMTEVCRKIALSATDLKIQSTAEGIRLYSFVCYYLDDLKVNWSHNGTGIKYTDRVKSGVTGEQIWLQINEPTQNDKGKYVMELFDGKTGHQKSVDLSGQAFDEAFAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPTPEVSWLKNEKPLTSDDHCSLKFEAGKTAFFTISGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARKGASEPPKGNQKSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52179-1", "uniprot_id": "MYOM1_HUMAN", "id": "P52179-1", "name": "Myomesin-1", "aln": "MSLPFYQRCHQHYDLSYRNKDVRSTVSHYQREKKRSAVYTQGSTAYSSRSSAAHRRESEAFRRASASSSQQQAS----------QHALSSEVSRKAASAYDYGSSHGLTDSSLLLDDYSSKLSPKPKRAKHSLLSGEEKENLPSDYMVPIFSGRQKHVSGITDTEEERIKEAAAYIAQRNLLASEEGITTSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTD-RAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDG---------ICTLLIT-------------------EFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALESLKGGKKAK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NUG4-1", "uniprot_id": "A0A8M1NUG4_DANRE", "id": "A0A8M1NUG4-1", "name": "", "aln": "----------------------------------------------MSESLKLQKEQEERDLETRYESSYHQSS--------------LSSVSRQSYTAYVSSHGHKISG-----KKKEKKLTPLSKKEKRSYLAVDKEDEVIG-YVVPVFRSSHLATQDLMETQEEVKEEGVGYVVMRNLFARESGFKMR------------------------------------------------------TVKKTRETSMRESAERMALSQKLHEKEQFQKKMNPDSLTHPPEFIVKPRGQTVWEGKSVTLHCTVAGWPKPRVAWYKNNVLIDAKARPEKYFTESQYNMHSLEIKNCTFSDTAEYRISALNVKGESSAFAPVIIKRFKEEEELVERPHGYS----------PEYGVTFNTTIIDKFDVSFGREGETMSLGCTVIVYPTVKRYQPEIVWYRNGVALSSSKWVHMHWSGEKATLTLVHLNKEDEGLYTLRVNTKSGFDTHSAYVFVRDADVEEEGVPVAPLDVRCHDANKDYVVVTWKQPAVEGSSAITGYFIDRLEVGNHHWTQCNDTPVKYARFPVTGLIEGRSYMFRVRALNNAGVSRPSRVSDPVVAMDPSDRARLRAGPSAPWTGVIKFTEEDPTVGVIPGPPTDLAVTEATKSYVVLSWKPPVQRGHEGVMYYVEKCLVGTDAWQRVNTGIPVKSPRFALFDLAEDKSYTFRVRSCNSAGVGEPSEETGATTVGDRLDLPSAPGPVIPIRNTDSSVVVCWGASKEVKDLVGYYIEVTVDGSGVWAPCNNKPVKGTRFVCHGLNATDKCTFRVKAVNAAGYSGSSAESEACLVKASI-------------------------------------------------------------------------------------------------AVPSPPTGVTTLERLRDYMVIGWQAPAKTGGADIRGYYLDYRTVKDGVTSKWHELNLKAVTSSPYKVTDLKENEFYQFQVRAFNQAGISEASIPTAPLECKEWTVAVPGPPHGLRVQEVRKDSMVVLWEPPTFNGRSPVTGYYVDFKEENGR---WRCVQERSTKHTYMKVSGLQEGISYRLRIHAKNLAGVGVPSKATDAILAETRPGTNEIVVDVDDNGVISLIFECSDLKEDSQFVWSKNYEAFTDSSRLTIQTTGGKSRAIFNDPSLDDLGIYSCVVTNTDGVSASYTLTEEGLKRLLDISHDHQFPIIPFKSEMAIELQEKGRVRFWAEVGKFTSNLQVEYVFNDNVIHEGKKYTMNFNKSTGIIEMFMDLLEVTDEGTFTFNLVDGKATGRTSLVLIGEEFAELQKKSEFERAEWVRRQGPHFVEYLSFEVTPECDVHLKCKVGNIKPATEIAWFKDGIEIEEDDEDAKKIGKSDEVLTFDIGKLVIKSEKAERKKKPATEESPSKPKISKKDAGVYEVKLKDERGKDKTLLNLTDAGYQAVLNEVFRVIANSSTELKVMSTEHGIILYSFVVHYLEDLRVGWLHKESKISHSDRVQCGVTGEQLWLKINEPTEKDKGKYAIDIFDGKGSVKRVLDLSGQVWEEAFEEFKRLKAAAIAERNRARVVGGLPDVVTIQEGKSLNLTGNVWGDPAPEVSWIKNEKPLVCDEHHTLKYEHSKFASITIAAVTTTDSGKYALLVKNKYGTEAAEFTVSVYIPEDEAEKKE-----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.* ::.:.* .: * :*:* *.***:: ::* . .* ::. .. ..:*:* .*: *:* *: :: :: . *:**:: . : ..: :::** :*...*:. *.*: *..: :*:*: :**.**.::* :.*.*.: :: *:* * * *.****:***.:**** :.*.***::****:**::****:* *:.:*.* **: **:*.**:***. * *.***:** **:**:** **:*.*::**:* * : * * *. *: : ****************** *:: * :*: ***: *****..:*.****: ***::****: ***********:**. . :: :**********.* **.*.***** . :*****::::******:*.*.* *****: ***.. *:********:**************:*****:*: *:. *****:**.*:**:::***:: ******* * .***:*: *::*******:*****:********** ******:**:**** .**: ****** :************.*.*** ****..********** * .*.***:**:*.*** :** ****:****.* **:.*:******* :* *** * ****:****:**.**** : :. ***:****** * * :*** ***:* * **** .:* ** :** **:**: * * ***:* ***::** * .**..**:* *:***:. .**:::**** .***** *:* **:. .* : ::*:***:*******.*: .****:*:*: *:**...**:*****:**:** ..: ** ::* : : *::* **:**:** :*::* * **** **. :..::*******:*:**:***:***** ***..:. .*:* ***:* . **.** :::.*.*:: *:* . **** *** **:***:::** : ** :**** :*::*:** :* ***:*:*: ***:**** :. *::.* :*:*:**:: *.** **.*::::.********: *: ****:**:: *****.::::**:*: : :***::**:* **:*:*****.****:*** **:* *****.*** *.*.*:** **. *::. * * * .*:*. ::******.*** ***:*****: *:*.* .:: :: ** : ** *:*:**: ** .** ***** :*::**:*.* *: : * ::***: ******:**:***** :*****.:::**** . :: :*****.::**: **:*** *****:*****:*************:**** ******.*****:****.*..*:* .**:* .: * :** .*:*:*****.*:******:*:::*****:***:**. ", "identical_positions": 810, "similar_positions": 412, "identity": "46.98%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2860", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P12688-1", "uniprot_id": "YPK1_YEAST", "id": "P12688-1", "name": "Serine/threonine-protein kinase YPK1", "aln": "---MYSWK-SKFKFGKSKEEKEAKHSGFFHSSKKEEQQNNQATAGEHDASITRSSLDRKGTINPSNS-SVVPVRVSYDASSSTST-----------VRDSNGGNSENTNSSQNLDETANIGSTGTPNDATSSSGMMTIKVYNGDDFILP------FPITSSEQILNKLLASGVPPPHKEISKEVDALIAQLSRVQIKNQGPADEDLISSESAAKFIPSTIMLPGSSTLNPLLYFTIEFDNTVATIEAEYGTIAKPGFNKISTFDVTRKLPYLKIDVFARIPSILLPSKTWQQEMGLQDEKLQTIFDKINSNQ--------------------DIHLDSFHLPINLSFDSAASIRLYN-----------------------HHWITLDNGLGKINISIDYKPSRNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLAR---VDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLG-YTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRD-AKDLLIGLLSRDPTRRLGYNG-ADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFDEEFTR------EKPIDSVVDEYLSESVQKQFGGWTYVGNEQLGSSMVQGRSIR---------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P18961-1", "uniprot_id": "YPK2_YEAST", "id": "P18961-1", "name": "Serine/threonine-protein kinase YPK2/YKR2", "aln": "---MHSWRISKFKLGRSKEDDGSSEDENEKSWGNGLFHFHHG-EKHHDGSPKNHNHEHEHHIRKINTNETLPSSLSSPKLRNDAS-----------FKNPSGIGNDNSKAS---ERKASQSSTETQ-GPSSESGLMTVKVYSGKDFTLP------FPITSNSTILQKLLSSGILTSSSNDASEVAAIMRQLPRYKRVDQDSAGEGLIDRAFATKFIPSSILLPGSTNSSPLLYFTIEFDNSITTISPDMGTMEQPVFNKISTFDVTRKLRFLKIDVFARIPSLLLPSKNWQQEIGEQDEVLKEILKKINTNQ--------------------DIHLDSFHLPLNLKIDSAAQIRLYN-----------------------HHWISLERGYGKLNITVDYKPSKNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLAR---VDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQG-YTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPA-AKDLLIGLLSRDPSRRLGVNG-TDEIRNHPFFKDISWKKLLLKGYIPPYKPIVKSEIDTANFDQEFTK------EKPIDSVVDEYLSASIQKQFGGWTYIGDEQLGDSPSQGRSIS---------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9WVC6-1", "uniprot_id": "SGK1_MOUSE", "id": "Q9WVC6-1", "name": "Serine/threonine-protein kinase Sgk1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTVKAEAARST------------------------LTYSRMRGMVAILIAFMK----QRRMG-----LNDFIQKIASN---------------------TYACKHAEVQSILKMSHPQEPELMN-----------------------ANPSPPPSPSQQINLG----PSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKN--VKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQP-YDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNS-ARHLLEGLLQKDRTKRLGAKDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFT-------EEPVPSSIGRSPDSILVTAS--VKEAAEAFLGFSYAPPVDSFL--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06226-1", "uniprot_id": "SGK1_RAT", "id": "Q06226-1", "name": "Serine/threonine-protein kinase Sgk1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTVKTEAARST------------------------LTYSRMRGMVAILIAFMK----QRRMG-----LNDFIQKLANN---------------------SYACKHPEVQSYLKISQPQEPELMN-----------------------ANPSPPPSPSQQINLG----PSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEAFYAVKVLQKKAILKKKEEKHIMSERNVLLKN--VKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQP-YDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLK-NITNS-ARHLLEGLLQKDRTKRLGAKDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFT-------EEPVPSSIGRSPDSILVTAS--VKEAAEAFLGFSYAPPMDSFL--------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00141-1", "uniprot_id": "SGK1_HUMAN", "id": "O00141-1", "name": "Serine/threonine-protein kinase Sgk1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTVKTEAAKGT------------------------LTYSRMRGMVAILIAFMK----QRRMG-----LNDFIQKIANN---------------------SYACKHPEVQSILKISQPQEPELMN-----------------------ANPSPPPSPSQQINLG----PSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKN--VKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQP-YDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNS-ARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFT-------EEPVPNSIGKSPDSVLVTAS--VKEAAEAFLGFSYAPPTDSFL--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZTW4-1", "uniprot_id": "SGK1_DANRE", "id": "Q7ZTW4-1", "name": "Serine/threonine-protein kinase Sgk1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTIQTETSVSAPD----------------------LTYSKTRGLVANLSAFMK----QRKMG-----LNDFIQKLSAN---------------------SYACKHPEVQSILNLTPPQDVELMN-----------------------SNPSPPPSPSQQINLG----PSSNPTAKPSDFDFLKVIGKGSFGKVLLARHRSDEKFYAVKVLQKKAILKKKEEKHIMSERNVLLKN--VKHPFLVGLHYSFQTTDKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQP-YDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNISNA-ARHLLEGLLQKDRTKRLGFTDDFTEIKNHMFFSPINWDDLNAKKLTPPFNPNVTGPNDLRHFDPEFT-------DEPVPNSIGCSPDSALVTSS--ITEATEAFLGFSYAPAMDSYL--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P11792-1", "uniprot_id": "SCH9_YEAST", "id": "P11792-1", "name": "Serine/threonine-protein kinase SCH9", "aln": "MMNFFTSKSSNQDTGFSSQHQHPNGQNNGNNNSSTAGNDNGYPCKLVSSGPCASSNNGALFTNFTLQTATPTTAISQDLYAMGTTGITSENALFQMKSMNNGISSVNNNNSNTPTIITTSQEETNAGNVHGDTGGNSLQNSEDDNFSSSSTTKCLLSSTSSLSINQREAAAAAYGPDTDIPRGKLEVTIIEARDLVTRSKDSQPYVVCTFESSEFISNGPESLGAINNNNNNNNNNQHNQNQHINNNNENTNPDAASQHHNNNSGWNGSQLPSIKEHLKKKPLYTHRSSSQLDQLNSCSSVTDPSKRSSNSSSGSSNGPKNDSSHPIWHHKTTFDVLGSHSELDISVYDAAHDHMFLGQVRLYPMIHNLAHASQHQWHSLKPRVIDEVVSGDILIKWTYKQTKKRHYGPQDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR--TNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFADIDWEALKQKKIPPPFKPHLVSETDTSNFDPEFTTASTSYMNKHQPMMTATPLSPAMQAKFAGFTFVDESAIDEHVNNNRKFLQNSYFMEPGSFIPGNPNLPPDEDVIDDDGDEDINDGFNQEKNMNNSHSQMDFDGDQHMDDEFVSGRFEI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : * : .: . . :.. . .: .: : : : .**..*:::***:**:* .::: : .**:*.: * *:.* * * :.**.:* . **:* *::***:. .**:* ::.*****:***:* * *::** **: ** **. :::************ :*:* * ****.* ::: *.*****.******:* * : **:* ** :::** * .*:: .: **.:* : : .. .: :: ***.:: .:*** . *:: * ** :.*. * * **::* : . * :** *** :: . : . : :. . ", "identical_positions": 118, "similar_positions": 116, "identity": "14.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2861", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UCQ1-1", "uniprot_id": "FOXK2_MOUSE", "id": "Q3UCQ1-1", "name": "Forkhead box protein K2", "aln": "-MAAAAALSGAGAPPAGG-----GAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSMGHSSFISRRHLEIFTPPGGG-HSAAAPEP--AQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSSEKREKQEAPESPVKPVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLSLMADNSQPENEKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLVEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEP---GASQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPPAIKPVTYTVATPVTTPTSQPPVVQTVHVVHQIPAVSVTSVAGLAPANTYTVAGQAVVTQAAVLAPPNPEPQENGDHREVRVKVEPVPAISPATLGAASRIIQTSQGTPVQTVTIVQQAPLGQHQLPIKTVTQNGAHVVPMPTAVHSQVNNAAASPLHMLATHASASASLPTKRQNGDQAEQPELKRVKAEDGESIVIALSVDAPPAAVREKAIQN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01167-1", "uniprot_id": "FOXK2_HUMAN", "id": "Q01167-1", "name": "Forkhead box protein K2", "aln": "MAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSMGHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSSEKREKQEASESPVKAVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLNLMADNSQPENEKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEP---GAAQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPQAIKPVTYTVATPVTTSTSQPPVVQTVHVVHQIPAVSVTSVAGLAPANTYTVSGQAVVTPAAVLAPPKAEAQENGDHREVKVKVEPIPAIGHATLGTASRIIQTAQTTPVQTVTIVQQAPLGQHQLPIKTVTQNGTHVASVPTAVHGQVNNAAASPLHMLATHASASASLPTKRHNGDQPEQPELKRIKTEDGEGIVIALSVDTPPAAVREKGVQN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QME9-1", "uniprot_id": "F1QME9_DANRE", "id": "F1QME9-1", "name": "Forkhead box protein K2", "aln": "-------MAGP------------------------VVARLEGREFEYLMKKRSVTVGRNSSQGSVDVSMGHSSFISRRHLEIFS------------------AGEDGAGEFYLRCLGKNGVFVDGAFQRRGAPPLQLPRACTLRFPSTNIKISFTALCSDQRECRGALEVPVK---AQISPLTISIPENITHLRSPLPSPTGTISAANSCPSSPRGAGLSSYRMGRGLTAEL--INENSQSEIDKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVARSQEEPGKGSFWRIDPSSEGKLMDQAFRKRRPRGVPCFRTPLGPLSSRSAPASPTHTGVLSAHSSGVQTPDS-SREGSPLPLEPEPSAAAAPQPKLAVIQESCFTQNTPGS-----PVLIAVQQPLQQSLKPVSFSVATPASSAAPQP-VMQTLHLLHQIPAACVFRAE-----------------------------QQNGDAQEVKVTVEPVPAVAAAP-GASSRVLQP-----------LAVAPRGQHQLPVKPITQNGTHVAAA--AIQGSAS--TASPLHMLATHASASASLPTKRQNGEQVEQPDSKRLKMEDGD------------AGQQQDHTD-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*. .*******************:***************************: . *..*:***************.*************.**:*********:****.*::** : * * *** .:******.**:.::** ************************ *.*::** :.::* : :***.* :***************************************************************************.****************:**.**::******************************.*:*********.***:* ****** ****** .*.*********: *:*.:*** ****:**: * ::***:::****.::.:.** *:**:*::*****..* . *:*** :**:*.***:**:. *. *::**::*. : ** ******:*.:****:**.. *::.... :*********************:**:* ***: **:* ***: *. ::. : ", "identical_positions": 402, "similar_positions": 108, "identity": "60.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2862", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P78536-1", "uniprot_id": "ADA17_HUMAN", "id": "P78536-1", "name": "Disintegrin and metalloproteinase domain-containing protein 17", "aln": "MRQSLLFLTSVVP----FVLAPRPPDDPGFGP--HQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGK-NESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHR---VKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYY-SPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGR---LQPAPVIPS-------APAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTD--HPVTRSEKAASFKLQRQNRVDSKETEC-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z0F8-1", "uniprot_id": "ADA17_MOUSE", "id": "Q9Z0F8-1", "name": "Disintegrin and metalloproteinase domain-containing protein 17", "aln": "MRRRLLILTTLVP----FVLAPRPPEEAGSGS--HPRLEKLDSLLSDYDILSLANIQQHSIRKRDLQSATHLETLLTFSALKRHFKLYLTSSTERFSQNLRVVVVDGK-EESEYSVKWQNFFSGHVVGEPDSRVLAHIGDDDVTVRINTDGAEYNVEPLWRFVNDTKDKRMLVYKSEDIKDFSRLQSPKVCGYLNADSEELLPKGLIDREPSEEFVRR---VKRRAEPNPLKNTCKLLVVADHRFYKYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGVQIEQIRILKSPQEVKPGERHFNMAKSFPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYY-NPTVKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKPGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGDAEDDTVCLDLGKCKAGKCIPFCKREQELESCACVDTDNSCKVCCRNLSGPCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHHSNIEMLSSMDSASVRIIKPFPAPQTPGRLQALQPAAMMPP-------VPAAPKLDHQRMDTIQEDPSTDSHADDDGFEKDPFPNSSTAAKSFEDLTD--HPVTRSEKAASFKLQRQSRVDSKETEC-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2R8Q3V6-1", "uniprot_id": "A0A2R8Q3V6_DANRE", "id": "A0A2R8Q3V6-1", "name": "", "aln": "MKPCIFYLVLLAPLFAHCAVKPVSVEEVSRNEEELQEFDALNSLLSDFEVLPASGLQLHSVRKRDADAHSHVERLVSFTALQRNFKLYLTTNTQLFTENFSAVFVDENGKEDQFDVQIQNYFKGHVVGEEHSRVQAHIDGDEFSAHIITEETEYNVEPLWRFTETPPDGRLLVYRSEDIKNISRLSSPKVCGYVNADAQELLPEEARAAEEMEEMKEEPHNRERRSTHDQKKNTCTLLLVADHRFYKHMGRAEESTTLNYLIELIDRVDDIYRNTSWDDD-FKGYGVQIQQIIINKDPTKVAPGEFHYNMDGSPTGRKDGVWDVKKLLEQFSYDIAANASRACLAHLFTYQDFDDGTLGLAYVAPSKP-GLGGLCPKPYYPSQSVKKPSYLNTGLTSTMNYGKTILTKEADLVTTHELGHNFGAEHDPDNIASCAPSDDQGGKYVMYPIAVSGDHVNNKHFSTCSKISVSKTLRIKVNQCFVERSSKLCGNSRVEEDEDCDPGLLHINDDPCCTSNCKFRKQAQCSDRNSPCCKNCMFESADKVCQEVITATCKGTSQCTGNSSECPTPGNLEDNTECVDKGRCQNGQCRPFCEAVHNLESCACNETENSCKVCCRKDE-LCTPFLNGGS-FLYLRKGKPCTVGFCDGAGKCMKQVQDVIERLWDFIDKLNINTFGKFLADNIVGSVVVFSLLFWIPISILVHCVDKRLDEQYEENTKMMYPSQMVLEVCSRALNSERRDTEQSGIGARPHSQGPSCTFTSSTTSALNGPYRPRLHTGTGDARRPRPSQPLRRTQSGSAANGHNRGGPQRRLLSPRRGGRLPAKRHSCQVLRGPHRTGNTITQETAEETGAH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :: *. :.* .: * . :: . . .:: *:*****:::*. :.:* **:**** :: :*:* *::*:**:*:******:.*: *::*: .*.** : :*.:: *: *::*.****** .*** *** .*:. :* *: :***:******.: . * *:***:*****:.***.*******::.* :****: * **: .. :**: : ****.**:*******::***.***** ********************: *****:**:** * *.* :* *** *:** * ...:...**** ******:*** :**:.************ ********...:. . **:***.** . ** ***:***** ******************************.:*.***.:***************** *** **.*** *: **:. *.::** ***.*:******:*.*:****::::*:*.**.*:*.:: .************* **:*:* ***.*.*****.* *********.**: **:* *:* *:*: *:* ***: ::****** :*:********. . *.*:::. . *:************* *** *:*******:*****:*.****************:****:****:*********:**:***. : : .. :*. . * : . .* *: :.. * *:*. *: : ** : :.* : . .... : :. . *..* . . :* ... ::** ", "identical_positions": 447, "similar_positions": 216, "identity": "52.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2872", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66HA4-1", "uniprot_id": "TAXB1_RAT", "id": "Q66HA4-1", "name": "Tax1-binding protein 1 homolog", "aln": "MTSFQE-----VPLQTSNFAHVIFQNVAKSYLPNAHLECHYTLTPYIHPHSKDWVGIFKVGWSTARDYYTFLWSPMPEQYVEGSTVNCVLAFQGYYLPNDDGEFYQFCYVTHKGEIRGASTPFQFRAASP-VEELLTMEDEGNSDMLVVTTKAGLLELKIEKTLKEKEELLKLVSVLEKETAQLREQVGRMERELSHEKSRCEQLQAEQKGLLEVSQSLRVENEEFMKRYSDATSKAHQLEEDIVSVTHKAVEKETELDSLKDKLRKAQQEKEQLECQLKTEKDEKELYKVHLKNTEIENTKLVSEIQTLKNVDGNKESMITHFKEEIGKLQSCLADKENLHRALLLTTSNKEDTLLLKEQLRKAEEQVQATRQELIFLAKELSDAVNVRDKTMADLHTARLENERVKKQLADTLAELQLHAVKTDQEKTDTLEH------------ELRREVEDLKLRLQMAADHYKEKFKECQRLQKQINKLSDQSASSNGVFTKRMGSQQKVNDASINTDPAAS--ASAVDVKPAASCAAETDFDMSAKDHVCEVTKEMAEKVEKYNKCKQLLQDEKAKCNKYADELAQMELKWKEQVRIAENVKLELAELEDSYSLQLAEKDKEINCLASFLENLSREKE-----LTKSLEDQKGRKMEGQSPQQVSRCLNTCSEQSGLLPTLPAAQP-VLQYGNPYTAHETRDGADGAFYPDEIQR-PPVRGPSW--EDNVVCSQPARNLSRPDGLEDPED--SREDENVPIPPDPANQHLRGHGAGFCFDSSFDVHKKCPLCELMFPPNYDQIKFEEHVESHWKVCPMCSEQFPPDYDQQGFERHVQTHFDQNVLNFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UKC1-1", "uniprot_id": "TAXB1_MOUSE", "id": "Q3UKC1-1", "name": "Tax1-binding protein 1 homolog", "aln": "MTSFQE-----VQLQTSNFAHVIFQNVAKSYLPNAHLECHYTLTPYIHPHSKDWVGIFKVGWSTARDYYTFLWSPMPEHYVEGSTVNCVLAFQGYYLPNDDGEFYQFCYVTHKGEIRGASTPFQFRAASP-VEELLTMEDEGNSDMLVVTTKAGLLELKIEKTLKEKEELLKLIAVLEKETAQLREQVGRMERELSQEKGRCEQLQAEQKGLLEVSQSLRVENEEFMKRYSDATAKVQQLEEDIVSVTHKAIEKETDLDSLKDKLRKAQHEREQLECQLQTEKDEKELYKVHLKNTEIENTKLVSEIQTLKNLDGNKESMITHFKEEISKLQSCLADKENLYRALLLTTSNKEDTLFLKEQLRKAEEQVQATRQELIFLTKELSDAVNVRDKTMADLHTARLENERVKKQLADTLAELQLHAVKKDQEKTDTLEH------------ELRREVEDLKLRLQMAADHYREKFKECQRLQKQINKLSDQAASTNSVFTKKMGSQQKVNDASINTDPAASTSASAVDVKPAASCA-ETGFDMSTKDHVCEMTKEIAEKIEKYNKCKQLLQDEKTKCNKYAEELAKMELKWKEQVKIAENVKLELAEVEDNYKVQLAEKEKEINGLASYLENLSREKE-----LTKSLEDQKGRKLEGQSPQQVSRCLNTCSEQNGLLPPLSSAQP-VLQYGNPYSAQETRDGADGAFYPDEIQR-PPVRVPSW--EDNVVCSQPARNLSRPDGLEDPED--SREDENVPIPPDPANQHLRSHGAGFCFDSSFDVHKKCPLCELMFPPNYDQTKFEEHVESHWKVCPMCSEQFPPDYDQQGFERHVQTHFDQNVLNFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86VP1-1", "uniprot_id": "TAXB1_HUMAN", "id": "Q86VP1-1", "name": "Tax1-binding protein 1", "aln": "MTSFQE-----VPLQTSNFAHVIFQNVAKSYLPNAHLECHYTLTPYIHPHPKDWVGIFKVGWSTARDYYTFLWSPMPEHYVEGSTVNCVLAFQGYYLPNDDGEFYQFCYVTHKGEIRGASTPFQFRASSP-VEELLTMEDEGNSDMLVVTTKAGLLELKIEKTMKEKEELLKLIAVLEKETAQLREQVGRMERELNHEKERCDQLQAEQKGLTEVTQSLKMENEEFKKRFSDATSKAHQLEEDIVSVTHKAIEKETELDSLKDKLKKAQHEREQLECQLKTEKDEKELYKVHLKNTEIENTKLMSEVQTLKNLDGNKESVITHFKEEIGRLQLCLAEKENLQRTFLLTTSSKEDTCFLKEQLRKAEEQVQATRQEVVFLAKELSDAVNVRDRTMADLHTARLENEKVKKQLADAVAELKLNAMKKDQDKTDTLEH------------ELRREVEDLKLRLQMAADHYKEKFKECQRLQKQINKLSDQSANNNNVFTKKTGNQQKVNDASVNTDPATS--ASTVDVKPSPSAA-EADFDIVTKGQVCEMTKEIADKTEKYNKCKQLLQDEKAKCNKYADELAKMELKWKEQVKIAENVKLELAEVQDNY------------------------KE-----LKRSLENPAERKMEGQNSQ-SPQCFKTCSEQNGYVLTLSNAQP-VLQYGNPYASQETRDGADGAFYPDEIQR-PPVRVPSWGLEDNVVCSQPARNFSRPDGLEDSED--SKEDENVPTAPDPPSQHLRGHGTGFCFDSSFDVHKKCPLCELMFPPNYDQSKFEEHVESHWKVCPMCSEQFPPDYDQQVFERHVQTHFDQNVLNFD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P132-1", "uniprot_id": "TXB1B_DANRE", "id": "Q6P132-1", "name": "Tax1-binding protein 1 homolog B", "aln": "MALFLEGTAASSAMETSNFAHVIFQNVGKSYLPHGALECHYTLTQFIKPHPKDWVGIFKVGWSTARDYYTFLWSPLPDNYTEGTAINRSVVFQGYYVPNDDGEFYQFCYVTHKGEIRGASTPFQFRANSPTEEELLTMEDEGGSDILVVTTKASYLEQKMEQIQQEKKELLENLDLLQKERDELIDEKNRLEKEYEQERESSAQLRKDVQELQLSAQSLQEEREEVKRRMEESTARLLQLEEDLIGVTQKGLQKETELDCLKDRVKKLNLEKEALEGQLKNEKDEKELYKIHLKNRELENTKLSAELQMLKSVDVNKENTIAQLKDELARVKSCLAEKEKQHRQLLANSSPSGESKALREQLRQKEEQLQATQQQANMLKAELRDSSNARDRSMAELYRIRVEAETLKKGQADARAECSRLEQQLEEMKSSTQQEAQCKESDVLAVAELQREVEDLRLRLQMAAEHYKDKYKECQKLQKQVVKFNEQQG-----VKRSPGSD--AAAGPLSASPEAS--------APGSPSTSDAVLDAIIHGRLKSSSKEL-DKNDKYRKCKQMLNEERERCSMITDELTKMEVKLREQMKTNESLRMQLAAEEDRYKSQVAEKGRELKELKDSLFVLTKEKEKLEGQLQKSVNREEEQKDSNLDVQSVFLQYPMPYAQDDPSPLLVPQRPTDLLFGNPYSSTDSRDGADGEFSDDQMPRLPPVGPPSW--DSNVVCIQPARNLSRPDGLEEPEEPQSTQNDDEPAAPEP-AEFLNDGQMPFCFEP-TGEQKRCPLCEVIFPPHYDQSKFEEHVESHWKICPMCSEQFPLDCDQQLFEKHVLTHFDSNVLNF-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * * ::************.*****:. ******** :*:**.************************:*::*.**:::* :.*****:****************************** ** **********.**:*******. ** *:*: :**:***: : :*:** :* :: .*:*:* .:*: . **: : : * :***: *.**. :* .::*:: *****::.**:*.::***:**.***:::* : *:* ** **:.*********:**** *:***** :*:* **.:* ***. *:::*:*:.::: ***:**: * :* .:* . :: *:****: ***:***:*: :* ** *: *.**::**:*: *:* * :** **: ** . : :: *:.* :. **:******:*******:**::*:****:****: *:.:* . ..: *.: . ..:.:.* :* *....: :: :* :.:: . :**: :* :**.****:*::*: :*. ::**::**:* :**:: *.::::** :* * ** * :*:: :* .. . * *.. * :* * :****:: ::****** * *:: * *** *** :.**** *****:*******:.*: * :::: * .*:* :.*.. ***:. . :*:*****::***:*** ***********:********* * *** **:** ****.***** ", "identical_positions": 398, "similar_positions": 223, "identity": "47.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2878", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UQ44-1", "uniprot_id": "IQGA2_MOUSE", "id": "Q3UQ44-1", "name": "Ras GTPase-activating-like protein IQGAP2", "aln": "------------MPHEELPSLQRPRYGSIVDDERLSAEEMDERRRQNIAYEYLCHLEEAKRWMEVCLVEELPPTTELEEGLRNGVYLAKLAKFFAPKMVSEKKIYDVEQTRYKKSGLHFRHTDNTVQWLRAMEAIGLPKIFYPETTDVYDRKNIPRMIYCIHALSLYLFKLGIAPQIQDLLGKVDFTEEEISNMRKELEKYGIQMPAFSKIGGILANELSVDEAALHAAVIAINEAIEKGVAKQTIITLRNPNAVLTCVDDSLSQEYQKELWEAKKKKEESAKLKNSCISEEERDAYEELLTQAEIQSNISTVN----------------------------------------------------------------------------------RMAAVDHINAVLQEGDPENTLLALKKPEAQLPAVYPFAAVMYQNELFNLQK-QNTSNYLAHEELLIAVEMLSAVALLNQALESSDLVAVQNQLRSPTIGFNNLDEAHVDRYADALLSVKQEALSQGQDTLSWNEIQNCIDMINNQIQEENDRMVVLGYINEAIDAGNPLKTLDTLLLPTANIRDVDPDCAQHYQDVLFYTKSQKLGDPKNVSKVLWLDEIQQAINEANVDENRAKQWVTLVVDVNECLDRKQSDHILTALKSSPSNIHNILPECANKYYDTLVKAKESKTDNESSEGSWVTLNVQEKYNYYYNTDSKEGSWVPPELCLSKESWLTGEEIEDIVEEVTSDYIREKLWSASEDLLVRFEATTLGPALREEFEARKAFLYEQTESVVKIQAFWKGFKQRQEYLHRQQVFAGNVDSVVKIQSWFRMVTARKSYLSRLRYFEDHKNEIVKIQSLLRASKARDDYKALVGSENPPLTVIRKFVYLLDQSDLDFQEELEVARLREEVVTKIRANQQLEKDLNLMDIKIGLLVKNRITLEDVISHRKKLNKKKG-GEIEILNNTDNKGIKSLSKERRKTLETYQQLFYLLQTKPSYLAKLIFQMPQNKSTKFMDTVIFTLYNYASNQREEYLLLKLFKTALEEEIKSKVDQVQDIVTGNPTVIKMVVSFNRGARGQNTLRQLLAPVVKEIIEDKALVINTNPVEVYKAWVNQLETQTGEASKLPYDVTTEQALTYPEVKNKLEASIENLRKVTDKVLGSIISSLDLLPYGLRYIAKVLKNSIREKFPDATEEELLKIVGNLLYYRYMNPAIVAPDGFDIIDMTAGGQINSNQRRNLGSVAKVLQHAASNKLFEGENEHLSSMNNYLSETYQEFRKYFQEACDVPEPEEKFNMDKYTDLVTVSKPVIYISIEEIINTHLLLLEHQDAIATEKSDLLNELLESLGEVPTVESFLGEGAVDPNDPNKENTLNQLSKTEISLSLTSKYDVKDGEAVDGRSLMIKTKKLIIDVTRNQPGSTLTEILETPATGQQELEHAKDMESRAVVDSRTPEEGKQSQAVIEDARLPLEQKKRKIQRNLRTLEQTGHVSSKNKYQDILNEIAKDIRNQRIHRKLRKAELSKLQQTLNALNKKAAFYEDQINYYDTYIKTCVDNLKR-------KNSRRSIKLDGKAEPKGTKRVKP--VRYTAAKLHDKGVLLGIDDLQTNQFKNVMFDIIATEDMGIFDVRSKFLGVEMEKVQLNIQDLLQMQYEGVAVMKMFDKVKVNVNLLIYLLNKKFYGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13576-1", "uniprot_id": "IQGA2_HUMAN", "id": "Q13576-1", "name": "Ras GTPase-activating-like protein IQGAP2", "aln": "------------MPHEELPSLQRPRYGSIVDDERLSAEEMDERRRQNIAYEYLCHLEEAKRWMEVCLVEELPPTTELEEGLRNGVYLAKLAKFFAPKMVSEKKIYDVEQTRYKKSGLHFRHTDNTVQWLRAMESIGLPKIFYPETTDVYDRKNIPRMIYCIHALSLYLFKLGIAPQIQDLLGKVDFTEEEISNMRKELEKYGIQMPSFSKIGGILANELSVDEAALHAAVIAINEAVEKGIAEQTVVTLRNPNAVLTLVDDNLAPEYQKELWDAKKKKEENARLKNSCISEEERDAYEELLTQAEIQGNINKVN----------------------------------------------------------------------------------RQAAVDHINAVIPEGDPENTLLALKKPEAQLPAVYPFAAAMYQNELFNLQK-QNTMNYLAHEELLIAVEMLSAVALLNQALESNDLVSVQNQLRSPAIGLNNLDKAYVERYANTLLSVKLEVLSQGQDNLSWNEIQNCIDMVNAQIQEENDRVVAVGYINEAIDEGNPLRTLETLLLPTANISDVDPAHAQHYQDVLYHAKSQKLGDSESVSKVLWLDEIQQAVDDANVDKDRAKQWVTLVVDVNQCLEGKKSSDILSVLKSSTSNANDIIPECADKYYDALVKAKELKSERVSSDGSWLKLNLHKKYDYYYNTDSKESSWVTPESCLYKESWLTGKEIEDIIEEVTVGYIRENIWSASEELLLRFQATSSGPILREEFEARKSFLHEQEENVVKIQAFWKGYKQRKEYMHRRQTFIDNTDSIVKIQSWFRMATARKSYLSRLQYFRDHNNEIVKIQSLLRANKARDDYKTLVGSENPPLTVIRKFVYLLDQSDLDFQEELEVARLREEVVTKIRANQQLEKDLNLMDIKIGLLVKNRITLEDVISHSKKLNKKKG-GEMEILNNTDNQGIKSLSKERRKTLETYQQLFYLLQTNPLYLAKLIFQMPQNKSTKFMDTVIFTLYNYASNQREEYLLLKLFKTALEEEIKSKVDQVQDIVTGNPTVIKMVVSFNRGARGQNTLRQLLAPVVKEIIDDKSLIINTNPVEVYKAWVNQLETQTGEASKLPYDVTTEQALTYPEVKNKLEASIENLRRVTDKVLNSIISSLDLLPYGLRYIAKVLKNSIHEKFPDATEDELLKIVGNLLYYRYMNPAIVAPDGFDIIDMTAGGQINSDQRRNLGSVAKVLQHAASNKLFEGENEHLSSMNNYLSETYQEFRKYFKEACNVPEPEEKFNMDKYTDLVTVSKPVIYISIEEIISTHSLLLEHQDAIAPEKNDLLSELLGSLGEVPTVESFLGEGAVDPNDPNKANTLSQLSKTEISLVLTSKYDIEDGEAIDSRSLMIKTKKLIIDVIRNQPGNTLTEILETPATAQQEVDHATDMVSRAMIDSRTPEEMKHSQSMIEDAQLPLEQKKRKIQRNLRTLEQTGHVSSENKYQDILNEIAKDIRNQRIYRKLRKAELAKLQQTLNALNKKAAFYEEQINYYDTYIKTCLDNLKR-------KNTRRSIKLDGKGEPKGAKRAKP--VKYTAAKLHEKGVLLDIDDLQTNQFKNVTFDIIATEDVGIFDVRSKFLGVEMEKVQLNIQDLLQMQYEGVAVMKMFDKVKVNVNLLIYLLNKKFYGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2CE93-1", "uniprot_id": "A2CE93_DANRE", "id": "A2CE93-1", "name": "", "aln": "MVKPQQSFRGSRMYHEDGANSLRPRYGSIVDDERLSAEEMDERRRQNIAYEYLCHLEEAKQWMEACLEEQLPPTTELENGLRNGVYLGKLAKFFAPQLVSEKKIYDRDQSWYKLSGLHFRHTDNTVQWLRAMESIGLPKIFYPETTDVYDRKNMPKVIYCIHALSLYLYKLGIAPQIQDLLGKVDFTEEEISNMRKELEKYGIQMPAFSKIGGILANELSVDEAALHAAVFAINEAIDKGHAENTMTALRNPNALLRNTEKALAQVYQDTLSKAKRKKEDQASGRRSSVATEERDVYEELLTQQEIQSNVDLVNTSSAVQRLHQALEAEDQKALLASLKLPALGLVGVTDENACFYLEHFTSYRQHKDAGLGAQLGKDEIQKVITSCNEFAEAEKRKQEAVVAINSAIRRGIPEETVEELLNPEAQMPIVYHTAASLYQAELFSLQLGSKNKAGLSHEELCVAVEMLSAVSVLNEVLDTKDSVAVIEQLSDSPLGFSGMDADNLQRYTDTLIHLREESLARGQEFLTWNDVQKCIDTVNVQVHEEHERVIAIAEINEALHSGDPEKTLAALLLSTAKLQGVKAANAKHYHDLLLTTKDHICKSSGDESAVLWLDQIQEAIYTANQNQEDALRLAAAVADINRAVCEEDAKATMSALQCPDAGLRAVMPECAQIYQSQLHQLQSTQTQQGTSGSSWVQHKIKDKYDYFYNIECKEGTWVEPEHFVHDSSQLSREDIQNVLSSVTAEYNREQLWLANEPFIIQLQALIRGYLVRRAHQDRLEYLRKQEPSVIKLQASWKGYKQRSVYKERLRTFQDSASTVVKLQSLVKMWRAKRSYTKRLQYFRDHEKEIVKIQAFLKANKARVDYTTLTGSQHPPLSVVRKFVHLLEQSSLDLQEEQDVTRLREEVVTKIRANQQMEKDLNLMDIKIGLLVKNRITLQDVVSHSKKMKSKKNKMSKEDLAMGEKQGIKGLSKEKRKKLEAYQHLFYLLQTNPSYLAKLIFQMPQNKSTKFMDTVIFTLYNYASNQREEYLLLKLFESALREEIKSKVDHIQEIVTGNPTVIKMVLSFYRGARGQNALRQLLGPVVKEIIEDKNLGINTNPVDIYKAWVNQLETATGEASKLPYEVTPEQALLHEEVRAKLESSNQVLRSVTDKVLGSIMSSLDNIPYGMRYIAKVLKDALHEKFPDATEDELLKIVGTLLYYRYMNPAIVAPDGFDIIDMTAGGQVHSEQRRNLASVAKMLQHAAANKLFEDESDHLTPMNSYISQTYQKFRGFFQAACDVPAPEEKFNVDEYSDMVTLSKPVIYISIEEIINTHSLVLEHKEAIAPDQSDLLHELLKDLGVVPDIESLLGEGTVDTNDLGKENSLSQHGKTEISLTLTNKFELLDGDDKDTKGLMTKTKKLIVDVVRIQPGETLTDILETPASATQEAEHAKLVERQVVQDSQTPEGLKSSQAMLEDRQLPLEQKKRKILRNLRTLEQAGLVNSKHKYQEVINDISKDIRYQRRYRQRRKAELVKLQQTLTALNSKTDFYQEQINYYDTYIKTCLDNLNRNNGYFFIRNSRRSIKLDRKDEEKGSKKSKASSLKYTAAKLHEKGVILEIEGVQINQFKNVMFDICPCEEVGDFEIKAKFMGVEMEKVQLHFQDLLQLQYEGVAVMKMFDKAKVNVNLLIFLLNKKFYGK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **: .. **************************************:***.** *:********:********.********::******** :*: ** *******************:*******************:*::***********:*************************************:***********************:*****::** *::*: :******:* .:. *: **. * .**:***:.* :.*.:: ****.******* ***.*:. ** : ** **:.: .* **:*: * :****:* ** ** :** ***.** .:. *:**** :********::**:.*::.* *:* :** ...:*:..:* ::**:::*: :: * *::**: *:**::*:*** :* *::**::*::.:. ****:. *:* :** :***.**:: .*.. *:**:*:* :*.: .. . * *****:**:*: ** ::: * : .: *.*:*..: :.:. ::.*:.. :. . ::****: * . * : :. :::. :* .**: :::.**:*:** :.**.:** ** : ..* *: ::*::::..** * **::* *.* ::::::* * :*. .: * :* :* .*:*:** ***:***. * .* :.* ....::**:** .:* *::** .**:**.**::******::*:*.*** **.:*.**::***:*:****:**:**.**:*** :*:***************:*********************:**:** **::.**. . * * :::***.****:**.**:**:*******:* ******************************************::**.********::*:************:** *******:*****.*******:** * ******::********** *********:**.**** : **: ***:* : ** ******.**:**** :***:********::::********:*******.***************************::*:*****.****:*****:*****.*.:**:.**.*:*:***:** :*: **:** ******:*:*:*:**:*************.** *:***::***.::.*** *** .** ** :**:****:**.** .* *:*.* .****** **.*::: **: * :.** ******:** * ***.***:******:. ** :**. : :.: **:*** * **:::** :********** ********:* *.*::***:::*:*:**** ** :*: ***** ******.***.*: **::************:***:* :*:******* * * **:*: *. ::*******:***:* *:.:* ****** *** . *::* *::::**:*********::*****:*************.********:*********", "identical_positions": 991, "similar_positions": 392, "identity": "58.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2879", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96SK2-1", "uniprot_id": "TM209_HUMAN", "id": "Q96SK2-1", "name": "Transmembrane protein 209", "aln": "MMQGEAHPSASLIDRTIKMRKETEARKVVLAWGLLNVSMAGMIYTEMTGKLISSYYNVTYWPLWYIELALASLFSLNALFDFWRYFKYTVAPTSLVVSPGQQTLLGLKTAVVQTTPPHDLAATQIPPAPPSPSIQGQSVLSYSPSRSPSTSPKFTTSCMTGYSPQLQGLSSGGSGSYSPGVTYSPVSGYNKLASFSPSPPSP-YPTTVGPVESSGLRSRYRSSPTVYNSPTDKEDYMTDLRTLDTFLRSEEEKQHRVKLGSPDSTSPSSSPTFWNYSRSMGDYAQTLKKFQYQLACRSQAPCANKDEADLSSKQAAEEVWARVAMNRQLLDHMDSWTAKFRNWINETILVPLVQEIESVSTQMRRMGCPELQIGEASITSLKQAALVKAPLIPTLNTIVQYLDLTPNQEYLFERIKELSQGGCMSSFRWNRGGDFKGRKWDTDLPTDSAIIMHVFCTYLDSRLPPHPKYPDGKTFTSQHFVQTPNKPDVTNENVFCIYQSAINPPHYELIYQRHVYNLPKGRNNMFHTLLMFLYIIKTKESGMLGRVNLGLSGVNILWIFGE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BRG8-1", "uniprot_id": "TM209_MOUSE", "id": "Q8BRG8-1", "name": "Transmembrane protein 209", "aln": "MMQGDVSPNPSLIDRTIKMRKETETRKVVLAWGLLNVSMAGMIYTEMTGKLISTYYNVTYWPLWYIELALASLFSLNALFDFWRYFKYTVAPTSLVVSPGQQALLGLKQAVVQTTPPRDLAATQISPSPPSPSIQGQSVLSYSPSRSPSTSPKFATSCMTGYSPQLQGLSSGGLGSYSPGVTYSPVSGYNKLASFSLSPSSP-YPTTVGPVESSGLRARYRSPPTVYNSPTDKEDYMTDLRTLDTFLRSEEEKQHRVKLGSPDSTSPSTSPTFWNYSRSVGDYAQTLKKFQYQLACRSQAPCANKDEADLISKQAAEEVWARVTMNRQLLDHMDSWTAKFRNWISETILVPLVQEIESVSTQMRRMGCPELQIGEASVTSLKQAALVRAPLIPTLNAIVQYLDLTPNQEYLFERIKELSQGGCMSSFRWNRGGDFKGRKWDTDLPTDSAIIMHVFCTYLDSRLPPHPKYPDGKTFTSQHFVQTPNKPDVTNENVFCIYQSAVNPPHYELIYQRHVYNLPKGRNNMFHTLLMFLYIIKTKESGMLGRVNLGLSGVNILWIFGE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F6P528-1", "uniprot_id": "F6P528_DANRE", "id": "F6P528-1", "name": "Transmembrane protein 209", "aln": "-MTPSKEGMTSLIERTIKLRKEEQARQVVLAWAVLNMSLAGMIYTEMSGKLLSRYYNITYWPIWYIELALASLFSLNALFDFWKYFKYTMAPSTIVVSPDQHRLLGLRGSGIQASPPQKQEKKEAPVSVQSSPLQGQNVLSFSPARPSSTSPKFSPSCVSGFSPPLSSTSSGG--------PFSPSMSFGKVLNYSPSQSSPPYPSSLGPAENTSLRSRYRTSPSVFNSPGGKEDCIDDLKTLEKFLRSEEEKSHRSQLGSPESTSPRHSPSFWNYNRTVGDYAQSLRKFQYQPACRSQAPSAHKDDTELGSKQAAEEVWARITTSRLVTDSIDSWTAKLRNWINDTILVHLVKEMDSINSQLRRMGCPELQIGEASISSLKQAAVVKASAIPTLNAIVQYLDVTPNQEYLVERIKELAHSGCMSSFRWNGGGDLKNRKWDTDLPTDSAILMHVLCTYLDSRLPPHPKYPDGKTFTSQHFMQTPNKPDVSNENLFCIHQSSTNPPHYQLVYQGHVYSLPKGRNNLFHTILMFLYIIKTKESGMLGRVNLGLSGVNVLWIFGD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .***:****:*** ::*:*****.:**:*:********:***:* ***:****:********************:*****:**:::****.*: ****: : :*::**:. .: . : *..:***.***:**:*..******:.**::*:** *.. **** .:** .:.*: .:* * .** **:::**.*.:.**:***:.*:*:*** .*** : **:**:.********.** :****:**** **:****.*::*****:*:***** *******.*:**:::* ***********:: .* : * :******:****.:**** **:*::*:.:*:**************::******:*:*. *****:******:*******.******::.********* ***:*.*************:***:*************************:********:***:***:**: *****:*:** ***.*******:***:**************************:*****:", "identical_positions": 380, "similar_positions": 130, "identity": "67.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2887", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L8N3-1", "uniprot_id": "A0ABK0L8N3_RAT", "id": "A0ABK0L8N3-1", "name": "DNA-directed RNA polymerase subunit beta", "aln": "-------------MDVLAEEFGSLTP-----EELAAPIPTVEEKWRLLPAFLKVKGLVKQHIDSFNYFINVEIKKIMKANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYTRGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILIQEQLSKNRIIVEADRK-GAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVIIFKAMGVESDQEIVQMIG-TEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWGGGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDN-KVDDRDYYGNKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPK-QRAAQFDVVK--HMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIIKLAGNLGVEDVNLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVSTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIDFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQI-PLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLAKYNE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59470-1", "uniprot_id": "RPC2_MOUSE", "id": "P59470-1", "name": "DNA-directed RNA polymerase III subunit RPC2", "aln": "-------------MDVLAEEFGSLTP-----EQLTAPIPTVEEKWRLLPAFLKVKGLVKQHIDSFNYFINVEIKKIMKANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYTRGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILIQEQLSKNRIIVEADRK-GAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVIIFKAMGVESDQEIVQMIG-TEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWGGGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDN-KVDDRDYYGNKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPK-QRAAQFDVVK--HMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIIKLAGNLGVEDVNLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVSTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIDFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQI-PLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLAKYNE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NW08-1", "uniprot_id": "RPC2_HUMAN", "id": "Q9NW08-1", "name": "DNA-directed RNA polymerase III subunit RPC2", "aln": "-------------MDVLAEEFGNLTP-----EQLAAPIPTVEEKWRLLPAFLKVKGLVKQHIDSFNYFINVEIKKIMKANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYTRGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILIQEQLSKNRIIVEADRK-GAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVIIFKAMGVESDQEIVQMIG-TEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWGGGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDN-KVDDRDYYGNKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPK-QRAAQFDVVK--HMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQI-PLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLSKYNE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QQA2-1", "uniprot_id": "F1QQA2_DANRE", "id": "F1QQA2-1", "name": "DNA-directed RNA polymerase subunit beta", "aln": "---------------MLQEEFGEMSP-----QQLAAPVDTVEEKWKLLPAFLKVKGLVKQHIDSFNYFINVEIKKIMKANEKITSDADPMWYLKYLNIYVGMPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYTRGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPMEFSKLNECPLDPGGYFIVKGQEKVILIQEQLSKNRIIVDQDRK-GTVGASVTSSTHEKKSRTNMIVKQGRFYLKHNTLSEDAPIAIIFKAMGVESDQEIVQMIG-TEEHVMAAFAPSLEECQKAQIFTQTQALRYIGNKVRRQRMWGG-PKKTKMEEARELLASTILTHVPVKEFNFRAKCIYLAVMVRRVILAQGDN-KVDDRDYYGNKRLELAGQLLSLLFEDLFKKFNSELKKIADQIIPK-QRAAQFDVVK--HMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSRLSFISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIIKLAFNLGVEDVNLLCGEELSYPTVFLVFLNGNILGVIRDHQKLVYTFRLMRRAGFINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKNGKPAVKNKHIEELSQGYRTFEDFLHESLVEYLDVNEENDCNIALYEHMISKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQRPMVKTKTIELIDFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLRRYTNQTFDKVMGPMLDAETRKPIWRHSILDADGICSPGEKVENKQVLVNKSMPTVTQT-PLEGSAQPGQPQYREVPVSYKGATDSYIEKVMISSNAEDAFLVKILLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGYPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLIRYGYNYQGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLARYNE-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25167-1", "uniprot_id": "RPC2_DROME", "id": "P25167-1", "name": "DNA-directed RNA polymerase III subunit RPC2", "aln": "MVELKMG-----DHNVEATTWDPGDS-----KDWSVPIKPLTEKWKLVPAFLQVKGLVKQHIDSFNHFINVDIKKIVKANELVTSGADPLFYLKYLDVRVGKPDIDDGFNITKATTPHECRLRDTTYSAPITVDIEYTRGTQRIKRNNLLIGRMPLMLRCSNCALTGKSEFELSKLNECPLDPGGYFVVRGQEKVILIQEQLSWNKMLT-EDFN-GVVQCQVTSSTHEKKSRTLVLSKHGKYYLKHNSMTDDIPIVVIFKALGVVSDQEIQSLIG-IDSKSQNRFGASLIDAYNLKVFTQQRALEYMGSKLVVKRFQSA-TTKTPSEEARELLLTTILAHVPVDNFNLQMKAIYVSMMVRRVMAAELDKTLFDDRDYYGNKRLELAGSLLSMMFEDLFKRMNWELKTIADKNIPK-VKAAQFDVVK--HMRAAQITAGLESAISSGNWTIKRFKMERAGVTQVLSRLSYISALGMMTRVNSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTEVEERPVMIVAFNAGVEDIREVSGNPINNPNVFLVFINGNVLGLTLNHKHLVRNLRYMRRKGRMGSYVSVHTSYTQRCIYIHTDGGRLCRPYVIVENRRPLVKQHHLDELNRGIRKFDDFLLDGLIEYLDVNEENDSFIAWNEDQIEDRTTHLEIEPFTLLGVCAGLVPYPHHNQSPRNTYQCAMGKQAMGMIGYNQKNRIDSLMYNLVYPHAPMVKSKTIELTNFDKLPAGQNATVAVMSYSGYDIEDALILNKASIDRGYGRCLVYKNSKCTVKRYANQTFDRIMGPMKDALTNKVIFKHDVLDTDGIVAPGEQVQNKQIMINKEMPAVTSMNPLQGQS--AQVPYTAVPISYKGPEPSYIERVMVSANAEEDFLIKILLRQTRIPEIGDKFSSRHGQKGVTGLIVEQEDMPFNDFGICPDMIMNPHGFPSRMTVGKTLELLGGKAGLLEGKFHYGTAFGGSKVEDIQAELERHGFNYVGKDFFYSGITGTPLEAYIYSGPVYYQKLKHMVQDKMHARARGPKAVLTRQPTQGRSREGGLRLGEMERDCLISYGASMLIMERLMISSDAFEVDVCRTCGRMAYCSWCHFCQSSANVSKISMPYACKLLFQELTSMNVVPKMILENY---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22276-1", "uniprot_id": "RPC2_YEAST", "id": "P22276-1", "name": "DNA-directed RNA polymerase III subunit RPC2", "aln": "MVAATKRRKTHIHKHVKDEAFDDLLKPVYKGKKLTDEINTAQDKWHLLPAFLKVKGLVKQHLDSFNYFVDTDLKKIIKANQLILSDVDPEFYLKYVDIRVGKK--SSSSTKDYLTPPHECRLRDMTYSAPIYVDIEYTRGRNIIMHKDVEIGRMPIMLRSNKCILYDADESKMAKLNECPLDPGGYFIVNGTEKVILVQEQLSKNRIIVEADEKKGIVQASVTSSTHERKSKTYVITKNGKIYLKHNSIAEEIPIAIVLKACGILSDLEIMQLVCGNDSSYQDIFAVNLEESSKLDIYTQQQALEYIGAKVKTMR----RQKLTILQEGIEAIATTVIAHLTVEALDFREKALYIAMMTRRVVMAMYNPKMIDDRDYVGNKRLELAGQLISLLFEDLFKKFNNDFKLSIDKVLKKPNRAMEYDALLSINVHSNNITSGLNRAISTGNWSLKRFKMERAGVTHVLSRLSYISALGMMTRISSQFEKSRKVSGPRALQPSQFGMLCTADTPEGEACGLVKNLALMTHITTDDEEEPIKKLCYVLGVEDITLIDSASLHLN--YGVYLNGTLIGSIRFPTKFVTQFRHLRRTGKVSEFISIYSNSHQMAVHIATDGGRICRPLIIVSDGQSRVKDIHLRKLLDGELDFDDFLKLGLVEYLDVNEENDSYIALYEKDIVPSMTHLEIEPFTILGAVAGLIPYPHHNQSPRNTYQCAMGKQAIGAIAYNQFKRIDTLLYLMTYPQQPMVKTKTIELIDYDKLPAGQNATVAVMSYSGYDIEDALVLNKSSIDRGFGRCETRRKTTTVLKRYANHTQD-IIGGMRVDENGDPIWQHQSLGPDGLGEVGMKVQSGQIYINKSVPTNSAD-APNPNNVNVQTQYREAPVIYRGPEPSHIDQVMMSVSDNDQALIKVLLRQNRRPELGDKFSSRHGQKGVCGIIVKQEDMPFNDQGIVPDIIMNPHGFPSRMTVGKMIELISGKAGVLNGTLEYGTCFGGSKLEDMSKILVDQGFNYSGKDMLYSGITGECLQAYIFFGPIYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCVIAYGASQLLLERLMISSDAFEVDVCDKCGLMGYSGWCTTCKSAENIIKMTIPYAAKLLFQELLSMNIAPRLRLEDIFQQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. :. : : . :**:*:****:********:****:*::.::***:***: : *..** :****::: ** ... . ..******** ****** ******** : * :: : *****:***..:* * . :::*************:*.* *****:***** *:::. * : * * ..*******:**:* : *:*: **:**::::: **.:::** *: ** ** .:: :. *. .* :. : .::** :**.*:* *: * . * :*. * : :*:::*:.*. :::: *.:* ::*.***: * : .***** *********.*:*::******::* ::* *: : * :* ::*.: ::: :** *: ***:***::*****:* ***:******:*********:.*****:*******:*****:****.:**********************: *: *: :. ****: : . : : *::**.::* ::* :* :** * :..::*: :. : .::* :****:*** :**.. :. *.: *: :* * *:*** .*:**********. ** *. * *********:**. ***:*********************:* *.*** :***:*:* :.**: ****:***** :::************************:***:*:***:*** . :::. .::**:*:* * ::* * . . *::*. *..**: * :*:. *: :**.:*: : . : . * * .*: *:*. *:*::**:* . :: *:*:****.* **:************* *:** ****** * ** **:******:******** :**:.****:*:* :.***.*****::*: * *:** *** . ***** *:***: **:********* **********:********:****:************:*.**** *::*************** ** :.*..** *:*: :: .: :***.******* ***: *:: * ", "identical_positions": 587, "similar_positions": 299, "identity": "50.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2891", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UHX1-1", "uniprot_id": "PUF60_HUMAN", "id": "Q9UHX1-1", "name": "Poly(U)-binding-splicing factor PUF60", "aln": "MATATIALQVNGQQGGGSEP-----AAAAAVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTN------LQMAAVTMGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAG-------AAVLGTLGTPG--LVSPALTLAQPLGT--LPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLG-----LLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UEB3-1", "uniprot_id": "PUF60_MOUSE", "id": "Q3UEB3-1", "name": "Poly(U)-binding-splicing factor PUF60", "aln": "MATATIALQVNGQQGGGSEPAAAAAAAAAAVVAAGDKWKPPQGTESIKMENGQSTGTKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTN------LQMAAVTMGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAG-------AAVLGTLATPG--LVSPALTLAQPLGA--LPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLG-----LLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSMASETHKAIQALNGRWFGGRKVVAEVYDQERFDNSDLSA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QZ57-1", "uniprot_id": "F1QZ57_DANRE", "id": "F1QZ57-1", "name": "", "aln": "-----MAVAVSAVNGG----------------------------EALMMENGQSTASKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMPNSLQMASLTMGFGDPLSPLQSVAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTLKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHPDLSDDDIKSVFEAFGRIKSCSLARDPTTGKHKGYGFIEYDKAQSAQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQMAWNLSQPENRTEDFLNCLEAVAGASILGAMTAGTGLSMPQLPQAVMAAQAPGVITGVTPARPAMPV-VPQVGLVNPVLSSPPTLSAAVAAAQEAKKEKEEEEALLDGLGQEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVGPEDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEVIVKIFVEFSAASEMNKAIQALNNRWFGGRKVIAEVYDQERFDNSDLSA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: *.. :** ::: *******.:********************************************* ****::*************:*************************************************:******************************************************************* ***************:****:******************:****:******************************************************** * .*. * : . : *:* . *. **********************.:** :*.**:***:*:*****. *.******** : :. ***************************************.*:*************************************:********* *** :*******.***.****:****************", "identical_positions": 456, "similar_positions": 45, "identity": "77.82%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2893", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LYD5-1", "uniprot_id": "F1LYD5_RAT", "id": "F1LYD5-1", "name": "", "aln": "MVNRGNCSKGCRTPVFVPETETQRGATGKMAASLIDVPQDILTFRNVAVDFSKEEWEYLDSSQRALYMDVMWENYSNLVFVENHCICGKYEEVVDQSSKHIVYQHANIEEKSYKCHELGKMLYDSSQSLLYNTSDTTENCKIYGSDNQWDHSNESLNLKAHKSRNTEEEQYKDCREHLNLCSIIGPYPQIDTGKKEHKITEYDRFFDSKHKLMIKRMCSGEKPYQCRKCGKCFRAYSSLYRHRRTHPGEKTYKLTECNKSILYFSHQKVHYNIHYGEKPYKCIECGKCNYHSSGFERHYRIHTGEETYKCYDCRKSFICYLGLKNHHKIHGGERPYECKQCSKSFYTLSHLENHYRTHRRQKLHRCNECGKSLSSSSGLQRHQRIHRGEKAYICAECDKCFIQKSQLKTHQKIHTGEKSYKCSECEKSFTVGSSLRIHQRIHTGEKPYKCSECHKCFIQQAHLRRHQKIHTGEKPYKCSECEKSFTVGSDLRMHQKIHTGEKPYKCSDCDKCFIQKAKLKKHQRIHTGEKPYKCSECEKCFTVVSDLRTHQKIHTGEKPYKCSECDKCFIRKANLRRHHRIHTGEKPYKCSDCGKCFIQKANLRTHERIHTGEKPYKCECGKSFSVGSDLRKHQKCHTGEKPYKCSECHKCFIRKAHLRRHQRIHTGEKPYKCSDCGKCFIQKANLRTHQKIHTGEKPYKCSDCDKCFIQKDHLRTHQRLHTGEKPYKCSECEKSFTGGSILRKHQKIHTARSLTNAMNLTNPLSKKPTLELIKEFIQERSLINAMYIAQSLPASHV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M6YWZ1-1", "uniprot_id": "A0A8M6YWZ1_DANRE", "id": "A0A8M6YWZ1-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------MDNKISQQEHFDDKTSNTPGPSEGAEVELEKPSTDAEEADQTKESAHNAEDADQINESAQPREELDKSDHASENTEGPSKLLSCSHCP-----FTNSKEENLREHVKKVHSTEVTETETAADPSLSCKCDVCGRSYRFS------------------------FLLKAHQRIHSKKHPVSKRSKSFSRSQAAHQHGPAPETSSQDDAEENTR-----------------------QKSYSCLYCRETFSSLSARRNHHRTHPEETLNQCTACGKKLSSQAALKRHKQIHEEKQSYNCSKCKSTFICSTSYKQHMLTHESERPFVC-TCGKGFKYRGALSAHKRTHTEDRPYRCLDCGKGFLYPGALTTHQKKHSKGNPEHCTQCHS------------------------STEKCVCSQS-------------------------------------QAEKSFKCPTCDKLFAFKSSLIRHKLTHTGERPFLCSDCGKGFLTFG---------------------------ELLKHQRYHTGHKPFQCTDCEKSFTQACYLQVHMRQHTGVRPYSCSQCDKSFYSSSHLKRHLRIHSGEKPFECLDCGKRFPQPYHLKVHFQTHMQKKPESKKSNE----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : *: ::::*: : .: . :. ::.:: :. : . :: *: *** : : . .:. . .: .: .:* ** *..**.:: *: : ..*.. : .. . . :* **:.:* :* :**::* : * .* *.:. .:. :: . . . .**. : ::.*.* * ::* :** .**:*** .:.*::*. ***.***.:.*:**::**. :::* *::*.. ** .:. * * * .*:.: * * *.*. .:* *:* ** ::**:* :* * *: . * *** *: :* :*::*.. . :**. .:: .**.:**. *** * *:.* **: ****:*: ****** *: . :* ***: ***.**::*::*.*.* : .:*: * * *** :**.**:*.*.* ..::*: * :**:****::* **.* * * **:.* : * :** . .. * ", "identical_positions": 156, "similar_positions": 187, "identity": "19.57%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2905", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z840-1", "uniprot_id": "D3Z840_RAT", "id": "D3Z840-1", "name": "", "aln": "------MDLKILSLATDKTTDKLQEFLQTLKADDLASLLESQAVKGRAVGTFLRAILKGSPCSEEDGALRRYKIYSCCIQLVESGDLQQDVASEIIGLLMLEVHHFPGPLLVDLANDFVGAVREDRLVNGKSLELLPIILTALATKKEGLTCGKGDLNGEECKRQLIDTLCSVRWAQRYVIQLTSVFKDVRLTPEEMKLVVAKVLTMFSRLNLQEIPPLVYQLLVLSSKGSRRSV--LDGIIAFFRELDKQHSAEQSSD--ELSELVTAPADELHHVEGTIILHIVFAIKLDCELGRELLKHLKAGQQGDPSKCLCPFSIALLLSLTRIQR-------FEEQVFDFLKTSVVKSFKDLQLLQGSKFLQTLVPQRTCVSTMILEVVKN-SVHSWDHVTQGLIEFGFILMDSYGPKKILDGKAVEIGSSLSKMTNQHACKLGADILLETFKIHEMIRQEILEQVLNRVVTRTSSPISHFLDLFSDIIMYAPLILQSCS-KVTETFDYLSFLPLQTVQGLLKAVQPLLKISMSMRDSLILVLRKALFASQLDARKSAVAGFLLLLKNFKVLGSLPSSQCTQSIG----VTQVHVDVHSRYSAVAN-----ETFCLEIIDSLKRCLGQQADVRLMLYEGFYDVLRRNSQLASSIMQTLFSQLKQFYEP--------EPDLLPPLKLGACVLTQGS---QTFLQEPLGHLLSCIQHCLAWYKSRVVPLQQGDEG-------EEEQEEEELYHELDDMLESITIRMIKSELEDFELDKSADFSQNNNVGIKNNICASLVMGVCEVLMEYNFSISNFSKSKSEEILSLFMCYKKFSDILSEKAGKGKAKMASKASDSLLSMKFVSDLLTALFRDSIQSHE-ESLSVLRSSSEFMHYALNVALQKVQQLTRTGCVSGPDGQNPDRIFQHLCDITRVLFWRYTSIPTSVEESAKKEKGKSISLLCLEALQKTFSAVLQFYQPKVQQFLQALDVMSTEEEE---AGVTVTQRASFQIRQFQRSLLNLLSSQEEDFNSKEALLLVTVLSTLSKLLEPTSPQFVQMLSWTSKICKEHSQEDASFCKSLMSLFFSLHVLYKSPVTLLRDLSQDIHGQLGDIDQDVEIEKTDHFAIVNLRTAAPTVCLLVLSQAEKVLEEVDWLITKIKGSVN-QETLSDEMTPEDASSQAVPPTVHIEKAITMQLGTLVTFFHELVQTALPSGSCVDTLLKDLSKIYSTLTAFVKYYLQVCQ---SSRR-IPNTVEKLVKLSGSHLTPVCYSFISYVQN---KSSNNPKCPEKEK--AAVSKSMAKVLRETKPIPNLVFAIEQYEKFLIQLSKKSKVN--LMQHMKLSTSRDFKIKGNVLDMVLR-------------------EEGEDENE------EGTASAH----------------------------TQQDREPAKKRRKKCLS------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K368-1", "uniprot_id": "FANCI_MOUSE", "id": "Q8K368-1", "name": "Fanconi anemia group I protein homolog", "aln": "------MDLKILSLATDKTTDKLQEFLQTLKDDDLASLLQNQAVKGRAVGTLLRAVLKGSPCSEEDGALRRYKIYSCCIQLVESGDLQQDVASEIIGLLMLEVHHFPGPLLVDLASDFVGAVREDRLVNGKSLELLPIILTALATKKEVLACGKGDLNGEEYKRQLIDTLCSVRWPQRYMIQLTSVFKDVCLTPEEMNLVVAKVLTMFSKLNLQEIPPLVYQLLVLSSKGSRRSV--LDGIIAFFRELDKQHREEQSSD--ELSELITAPADELYHVEGTVILHIVFAIKLDCELGRELLKHLKAGQQGDPSKCLCPFSIALLLSLTRIQR-------FEEQVFDLLKTSVVKSFKDLQLLQGSKFLQTLVPQRTCVSTMILEVVRN-SVHSWDHVTQGLIEFGFILMDSYGPKKILDGKAVEIGTSLSKMTNQHACKLGANILLETFKIHEMIRQEILEQVLNRVVTRTSSPINHFLDLFSDIIMYAPLILQNCS-KVTETFDYLTFLPLQTVQGLLKAVQPLLKISMSMRDSLILVLRKAMFASQLDARKSAVAGFLLLLKNFKVLGSLPSSQCTQSIG----VTQVRVDVHSRYSAVAN-----ETFCLEIIDSLKRSLGQQADIRLMLYDGFYDVLRRNSQLASSIMQTLFSQLKQFYEP--------EPDLLPPLKLGACVLTQGS---QIFLQEPLDHLLSCIQHCLAWYKSRVVPLQQGDEG-------EEE--EEELYSELDDMLESITVRMIKSELEDFELDKSADFSQNTNVGIKNNICACLIMGVCEVLMEYNFSISNFSKSKFEEILSLFTCYKKFSDILSEKAGKGKAKMTSKVSDSLLSLKFVSDLLTALFRDSIQSHE-ESLSVLRSSGEFMHYAVNVTLQKIQQLIRTGHVSGPDGQNPDKIFQNLCDITRVLLWRYTSIPTSVEESGKKEKGKSISLLCLEGLQKTFSVVLQFYQPKVQQFLQALDVMGTEEEE---AGVTVTQRASFQIRQFQRSLLNLLSSEEDDFNSKEALLLIAVLSTLSRLLEPTSPQFVQMLSWTSKICKEYSQEDASFCKSLMNLFFSLHVLYKSPVTLLRDLSQDIHGQLGDIDQDVEIEKTDHFAVVNLRTAAPTVCLLVLSQAEKVLEEVDWLIAKIKGSAN-QETLSDKVTPEDASSQAVPPTLLIEKAIVMQLGTLVTFFHELVQTALPSGSCVDTLLKGLSKIYSTLTAFVKYYLQVCQ---SSRG-IPNTVEKLVKLSGSHLTPVCYSFISYVQN---KSSDAPKCSEKEK--AAVSTTMAKVLRETKPIPNLVFAIEQYEKFLIQLSKKSKVN--LMQHMKLSTSRDFKIKGSVLDMVLR-------------------EDEEDENE------EGTASAH----------------------------TQQDREPAKKRRKKCLS------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NVI1-3", "uniprot_id": "FANCI_HUMAN", "id": "Q9NVI1-3", "name": "Fanconi anemia group I protein", "aln": "------MDQKILSLAAEKTADKLQEFLQTLREGDLTNLLQNQAVKGKVAGALLRAIFKGSPCSEEAGTLRRRKIYTCCIQLVESGDLQKEIASEIIGLLMLEAHHFPGPLLVELANEFISAVREGSLVNGKSLELLPIILTALATKKENLAYGKGVLSGEECKKQLINTLCSGRWDQQYVIQLTSMFKDVPLTAEEVEFVVEKALSMFSKMNLQEIPPLVYQLLVLSSKGSRKSV--LEGIIAFFSALDKQHNEEQSGD--ELLDVVTVPSGELRHVEGTIILHIVFAIKLDYELGRELVKHLKVGQQGDSNNNLSPFSIALLLSVTRIQR-------FQDQVLDLLKTSVVKSFKDLQLLQGSKFLQNLVPHRSYVSTMILEVVKN-SVHSWDHVTQGLVELGFILMDSYGPKKVLDGKTIETSPSLSRMPNQHACKLGANILLETFKIHEMIRQEILEQVLNRVVTRASSPISHFLDLLSNIVMYAPLVLQSCSSKVTEAFDYLSFLPLQTVQRLLKAVQPLLKVSMSMRDCLILVLRKAMFANQLDARKSAVAGFLLLLKNFKVLGSLSSSQCSQSLS----VSQVHVDVHSHYNSVAN-----ETFCLEIMDSLRRCLSQQADVRLMLYEGFYDVLRRNSQLANSVMQTLLSQLKQFYEP--------KPDLLPPLKLEACILTQGD---KISLQEPLDYLLCCIQHCLAWYKNTVIPLQQGEEE-------EEE--EEAFYEDLDDILESITNRMIKSELEDFELDKSADFSQSTSIGIKNNICAFLVMGVCEVLIEYNFSISSFSKNRFEDILSLFMCYKKLSDILNEKAGKAKTKMANKTSDSLLSMKFVSSLLTALFRDSIQSHQ-ESLSVLRSSNEFMRYAVNVALQKVQQLKETGHVSGPDGQNPEKIFQNLCDITRVLLWRYTSIPTSVEESGKKEKGKSISLLCLEGLQKIFSAVQQFYQPKIQQFLRALDVTDKEGEEREDADVSVTQRTAFQIRQFQRSLLNLLSSQEEDFNSKEALLLVTVLTSLSKLLEPSSPQFVQMLSWTSKICKENSREDALFCKSLMNLLFSLHVSYKSPVILLRDLSQDIHGHLGDIDQDVEVEKTNHFAIVNLRTAAPTVCLLVLSQAEKVLEEVDWLITKLKGQVS-QETLS-----EEASSQATLPNQPVEKAIIMQLGTLLTFFHELVQTALPSGSCVDTLLKDLCKMYTTLTALVRYYLQVCQ---SSGG-IPKNMEKLVKLSGSHLTPLCYSFISYVQN---KSKSLNYTGEKKEKPAAVATAMARVLRETKPIPNLIFAIEQYEKFLIHLSKKSKVN--LMQHMKLSTSRDFKIKGNILDMVLR-------------------EDGEDENE------EGTASEH----------------------------GGQNKEPAKKKRKK---------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PUU2-1", "uniprot_id": "A0A8M9PUU2_DANRE", "id": "A0A8M9PUU2-1", "name": "", "aln": "MSKMKVTVDSILSLSETDDGDELQKHLTLLSDDQLTTMLTNSALKGKDTGILIKAIFKGSPVSVSHGANRRLLVYKHCIPLCESGDLQTEVASDIIGLLMLDTHSLPGPALATLASLYVDAIKVGEMNSGRSLELFPTILTALSAT-DALAYGKGELTGNEYKKQLINSLCSSRWDPQCVIHLTTMFRDVPLSTEELQFLIEKILRMFLKLDLQEIPPLVYQLLLLSAKGCKKLV--LEGIINYFKKQDQLQKEEQRNGECEDVEVQTIPQDQLRHVEGTVILHIVFAIRLDHELGREFFKNLKVAQ----SDPLCPFSIALLLSVARIQR-------YEEQVFEFLKGAITKNFKDDQIQNSSKFLQDLLPQFSSVSDMILDTVKN-SVFGWDHVTQGLVQLGFILMDSFGPKPGPFGKVTEGTSSTAKTPNQLACRLGGQVLLESFKMHEPIRGEILEQVLNRLVTKTASPVTHFIDLLSSIVLSAPMILLESSSKVTETFDQLSYLPLSTVQGLLKAVQPLLKVSMSMKDALILVLRKAMFSSHLDGRKSAVAGFLLLLKNFRILGSLASSQASQAIT----SSQVQADVHSRYNTAAN-----EAFCLEILSSLRRCLNQQADVRLMLYEGFHDVLRRNSQLASSITQTLLSQLKRYFEP--------EQDLLPPVKLESCISAQGD---QVFLQEPLAHLLCCTVHCLLWNQNVRSGGNVSDDE-------DDEEDVGGVESELQAMLESITKRMIKSELEDFELDKCAEFSTGSSVGVKNSIYAVLVMGLNEVLMEYNFITANYSKNHFEDVLELFKRYLKVCDILRERAGKGRP-ASSKTPRSLLSLGFVSTLLTALFRDSTQSRE-ESLSVLRSNGDFLRYSVSVALQKIQQLEETGHTDGPEGQSPDKTFRHLCDITSVLMWRYTNVPSTVEDAGKKEKGQSVSLLCLEGLLRVFTTVLQRYPTRVSNFLSSLDVSGEGEGD----KSDLTEQTAFYIRQFQRALMNQLSGPEEEFNSKEAQLLVSILSVLSRQLSPSSQQFLQMITWTVKICKETNFEDIALTKGLLSLLFSLYVLHKSPVSLLWEMCQDIHSQLGDIDQDVEVEKQSHFAIICMKTAASTT-LQVLSQVGKVLDEVDWLIAKKKAQISSDRTIS------GNTQQPLGQQDPIEKAITIQLGTLLTALHELVQTALPTGACTDTLMRELSRTYCILTTLTKYYIQLCA---TQPGQLPARLEKLVKLSGSHLTPQCYCFITYVQSGELTAGGSEKLKKKKKEEEAVAAASAKVLRETKAIPNLIFNIEQYEKFLILLSKKSKVN--LMQYMKLSTSRDFRINAATLEAALQ-------------------EQEQDQSQ------QVSLSKQPHLQTHLQEFSRFQCFFPSVFRVKMLRVKHQRKKGGRSERRSLQSLFCTFPPSYLFISG----------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7L1-1", "uniprot_id": "FANCI_DROME", "id": "A1Z7L1-1", "name": "Fanconi anemia group I protein homolog", "aln": "----------MRSLGEKARFDELELLIQNTPIEKLKETLKSTMTRSE-GITYWNYLLRGFNPESKDALAKRFECVRSFMDGLSSTELSYKQTFDLITRLSQDLATFPSEQLAWIVEHCMDGIRQGDAKCVGWKDLLPDALSLLLARPRFLLNGIS-IDGMEFRDTTVRSIATMQWPASILTPIADMFKTMNLSSGEIVTVLNKFSGALQELSPMELPALCFQLFSMCSTASQLIIPLLALEKYFHRNYYKRLFSDMCSNSTNLDSIDLFSDKELREAEETILHHLNYCT--MYKLTEKHLAIMLRNFLHMPDVILTPFMLSAIISMTSINRDPESARISHSILLPFLRNVIKNNEEERTLADYSVWYRDTLQRKQVDLQQVLTVLIDQNKDGKDVITPGLVHLVFYLLKSQSPK---------------------MHTLAITFLTKFIRKRFIFGQGIIKLISEWMIVYQEQ--NQFSECLTLLSVADTYTVSECMKPIQSVLEHMQWLSGEQSMRMMNFILPLLKISNRVRDALIDVLCKAMSSSGIQKRRMAIYGFCMILKQLNNSNAVRQTSSATSFCTQHSISGYSIMTQNTLGSRSNPQRNFDMLTLEIIGMLRNCLQQQFDIRCSLYENLQRAVELNAKLVPHVLQVIDWHFRSFFDTPSAEDAGDDLDTVFRIRYDQLVSSSDDQHMEIQLKDNLGKLIQFVANCLAVFDRAPSGYDTREMNRLMSFCVDRMVANRLPLEEITPPATHLKCALVLQQLNIIEGIICHLLLKSKPQ--NNAVCQILPLFNQHCKLLESLKALSDASKKAHKQLKQTAKNNSTSTCNLTLNG-VPVKTMCTQPDNIWDLAILDKLLHLLLDDVVAFAAPEKTVLLRSNEPLVRYVLSVTASRVESIRLEPDYK--QLAYSKRTFKQLTDITKVIYERCIQRLPELWKNFDMQS----AALATQCFSECLKTAHETYSKKFEDFVKSFDLASIKGSR----NKEVVYTIQDVLDDFMTEYGTDDSICKNEFVSKLPVYLLESLEILLDHIDYQDRAATESYTWLLNFCSKNEILNSEMGLVHRMLFVQRQKTHLG--PFFDSVARQLGHVLGVQNEDAPSESVELTLKSISTVTIESCLQHLYAAIQKQLNDVDYFVTKANNLNYKCQVVP-----EIDQIYWRGNLDSMDRSICTQIIHISRTLLVLTNVCIPLGSLMDGLMKLLIQHYTCLKSLTKHYISSYTSDTSIENIKSTKFELLLRAVGKQLPANIYELITYIEAN-----TLDEEAQQHTKKRKVQAERAKVLRETRLIPKVIMVIEDFNKHIILLSKKTKSKNRLTDYLHLGTMRDFDIKSTDLRAAIERSISDGRNISTEDSNAEDRDEDEDENENVEEDDDAQSTTYPEDLEEKEDECLVIEKKEERRRRRAPSSEAEDPQPKRKRGRKAAEQLEAEDEEQVEEEQPETTLKLRRNKKVEPKTKRSVAIKKPEEQPSHESRTSKRSKGPADKQTAEPAKVDLCVPEVPAEKKKPQPSRRLGIPRTLRK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **. *:*: : .* * . :.. . :::* . . . :* : .* :*. . : ::* * : :*. *. :.. :..:: . :*:* *: * : * * . : * * : : ::.: :* : :: :*: : *:. *: :: * : .:. *:*.* :**: :.:...: : * :. : : .. : .: . :* ..* *:: *: :. :* .: . : . * ** :: ::*:: *:* .. :: :*: : :. :: : : * : : : : :* .: : . . * :* **:.: * *:.* .** *. .* : :: : : *:: : : ::. . .:* : :: : : . : .. : ..:: : :*. . ::: : ****:* ::*.** ** **: :. :: *: *: ** ::**::. .:: .:..: :: : .:. .: :* : : ***:. *:..* ** *:* **:.: .:. *::*. : *.: ::: :::. . * : :: : :... : *:: * *: :** . : : : :: :. :: .:*: :* . : .. :* : * : . : .: . :..: .. *. . . * . . .: .: ::. ** *: * *. :***. :::* :.*: .:::.: . : ..: *::* *** *: * . . : . . :. : *. : : . :... : * :..:*: ::*: . :. : :* . * :::* ** . *: * * :. . : :* ::*.: . : : *:.. : . :: .:.::: ** ::*. *. . .: : : : * *::**::::* : ..:. ::::* *: : : *.:..:* *: * *:: * : * *.::.::*:. : . .* *:: *.:*.. * :*:*:: ::. * *:*****: **:::: **:::*.:* ****:* : * ::::*.* *** *:. * .:. :: :*:.: : : : : :.. :. ", "identical_positions": 192, "similar_positions": 481, "identity": "12.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2908", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q811W2-1", "uniprot_id": "CP26B_MOUSE", "id": "Q811W2-1", "name": "Cytochrome P450 26B1", "aln": "-----------------MLFEGLELVSALATLAACLVSVTLLLAVSQQLWQLRWAATRDKSCKLPIPKGSMG---FPLIGETGHWLLQGSGFQSSRREKYGN-VFKTHLLGRPLIRVTGAENVRKILLGEHQLVSTEWPRSARVLLGPNTVANSIGDIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWS-----SQPEAINVYQEAQRLTFRMAVRVLLGFSIPEEDLGHLFEVYQQFVEN--VFSLPVDLPFSGYRRGIQARQILQKGLEKAIREKLQCTQG------------KDYSDALDILIESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPAVLEKLREELRAQGLLHGGGCPCEGTLRLDTLSSLRYLDCVIKEVMRLFTPVSGGYRTVLQTFELDG-FQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPR-ITLVPVLHPVDGLSVKFFGLDSNQNEILPETEAMLSATV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V7X8-1", "uniprot_id": "CP26B_RAT", "id": "G3V7X8-1", "name": "Cytochrome P450 26B1", "aln": "-----------------MLFEGLELVSALATLAACLVSVTLLLAVSQQLWQLRWAATRDKSCKLPIPKGSMG---FPLIGETGHWLLQGSGFQSSRREKYGN-VFKTHLLGRPLIRVTGAENVRKILLGEHQLVSTEWPRSARVLLGPNTVANSIGDIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWS-----SQPEAINVYQEAQRLTFRMAVRVLLGFSIPEEDLGNLFEVYQQFVEN--VFSLPVDLPFSGYRRGIQARQILQKGLEKAIREKLQCTQG------------KDYSDALDILIESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPAVLEKLREELRAQGLLHGGGCPCEGTLRLDMLSGLRYLDCVIKEVMRLFTPVSGGYRTVLQTFELDG-FQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPR-ITLVPVLHPVDGLSVKFFGLDSNQNEILPETEAMLSATV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NR63-1", "uniprot_id": "CP26B_HUMAN", "id": "Q9NR63-1", "name": "Cytochrome P450 26B1", "aln": "-----------------MLFEGLDLVSALATLAACLVSVTLLLAVSQQLWQLRWAATRDKSCKLPIPKGSMG---FPLIGETGHWLLQGSGFQSSRREKYGN-VFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRSTRMLLGPNTVSNSIGDIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWS-----SHPEAINVYQEAQKLTFRMAIRVLLGFSIPEEDLGHLFEVYQQFVDN--VFSLPVDLPFSGYRRGIQARQILQKGLEKAIREKLQCTQG------------KDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFELDG-FQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPR-ITLVPVLHPVDGLSVKFFGLDSNQNEILPETEAMLSATV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6EIG3-1", "uniprot_id": "CP26B_DANRE", "id": "Q6EIG3-1", "name": "Cytochrome P450 26B1", "aln": "-----------------MLFESFDLVSALATLAACLVSMALLLAVPQQLWQLRWTATRDKSCKLPMPKGSMG---FPIIGETCHWFFQGAGFHASRRQKYGN-VFKTHLLGRPLIRVTGAENVRKVLMGEHSLVTVDWPQSTSTLLGPNSLANSIGDIHRKRRKIFAKVFSHEALESYLPKIQQVIQETLRVWS-----SNPDPINVYRESQRLSFNMAVRVLLGFRIPEEEMHCLFSTFQEFVEN--VFSLPIDLPFSGYRKGIRARDSLQKSIEKAIREKPLHTQG------------KDYTDALDVLLESAKENNTELTMQELKESTIELIFAAFATTASASTSLVMQLLRHPAVLEKLREELRSCGLLHDG-CLCQGELRLDSIISLKYLDCVIKEVLRLFAPVSGGYRIATQTFELDG-VQVPKGWSVMYSIRDTHDTSAVFKDVEAFDPDRFSPERSEDREGRFHYLPFGGGVRSCLGKQLATLFLKLLAVELAGGSRFELSTRTFPR-MISVPVVHPTDGLRVKFFGLDSNQNQIMAKSDEMLDATV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P54781-1", "uniprot_id": "ERG5_YEAST", "id": "P54781-1", "name": "C-22 sterol desaturase ERG5", "aln": "MSSVAENIIQHATHNSTLHQLAKDQPSVGVTTAFSILDTLKSMSYLKIFATLICILLVWDQVAYQIKKGSIAGPKFKFWPIIGPFLESLDPKFEEYKAKWASGPLSCVSIFHKFVVIASTRDLARKILQSSKFVKPCVVDVAVKILRPCNWVFLDGKAHTDYRKSLNGLFTKQALAQYLPSLEQIMDKYMDKFVRLSKENNYEPQVFFHEMREILCALSLNSFCGNYITEDQVRKIADDYYLVTAALELVNFPIIIPYTKTWYGKKTADMAMKIFENCAQMAKDHIAAGGKPVCVMDAWCKLMHDAKNSNDDDSRIYHREFTNKEISEAVFTFLFASQDASSSLACWLFQIVADRPDVLAKIREEQ-----LAVRNNDMSTELNLDLIEKMKYTNMVIKETLRYRPPVLMVPYVVKKNFPVSPNYTAPKGAMLIPTLYPALHDPEVYENPDEFIPERWVEG-SKASEAKKNWLVFGCGPHVCLGQTYVMITFAALLGKFALYTDFHHTVTPLSEKIKVFATIFPKDDLLLTFKKRDPITGEVFE----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : *. .* * .::. :: : : * .. : ***:. * : :: . . : *:.. :. : : :: ::.:.:: : :: . :*. : :* * . *. * . ** : :*:::** .***.:: :::. : : .: :. .::* :.: :::. : * *.*::: : . : .. :..:*: :*:: * :: : * :*:. : . * ** : :.:: *:* :*:.:..: ::**: :::* : *. : :* ** *:*:* * . *.** : ::* : ****.:* .*: . :.* :. *** :: :: : . . *::: : * *:*: *: :.: ::* ** * : ***: . : : * ::* : *. :. .:.. : ...:.* *.* :.* *. .::: ", "identical_positions": 82, "similar_positions": 194, "identity": "14.8%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2912", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9P0P8-1", "uniprot_id": "MRES1_HUMAN", "id": "Q9P0P8-1", "name": "Mitochondrial transcription rescue factor 1", "aln": "MAMASVKLLAGVLRKPDAWIGLWGVLRGTPSSYKLCTSWNRYLYFSSTKLRAPNYKTLFYNIFSLRLPGLLLSPECIFPFSVRLKSNIRSTKSTKKSLQK-VDEEDSDEESHHDEMSEQEEELEDDPTVVKNYKDLEKAVQSFRYDVVLKTGLDIGRNKVEDAFYKGELRLNEEKLWKKSRTVKVGDTLDLLIGEDKEAGTETVMRILLKKVFEEKTESEKYRVVLRRWKSLKLPKKRMSK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CQF4-1", "uniprot_id": "MRES1_MOUSE", "id": "Q9CQF4-1", "name": "Mitochondrial transcription rescue factor 1", "aln": "MAVPGVRLLTGALRKPDAWTRLWGVIQGT-SSHKLCASWNRYLYFSSTKLNTSNYKTLFRNIFSLRLPELLVSPECYFPFSIRLKSNINSKKSTKKTLQKEADEEDSDEETSYPERSEQEEELESEPGVAKDYKDLEKVVQSFRYDVILKTGLDVGRNKVEDAFYKGELRLNGEKLWKKSRTVKVGDTLDLITGENKETGTEVVMRILLKKVYEEKTENDKHRVVLRRWKSLKLPKKTLSK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B7ZD93-1", "uniprot_id": "B7ZD93_DANRE", "id": "B7ZD93-1", "name": "", "aln": "--MQSLSVQALALRQLGRLNSLQLLTPCHGSGLSMWCPRMLHARQLWGSATSQTHRTAMG-------PKSWDARQSWTLHQIRLKS------TRKKGKQKAVHQEETEEET-----SDYEDEFPDDPGLPNNYKDNEKVVQSLRFDLVLKSGLDIARHSVEDSFYSLKLRLNGQKLSKKGKLVKVGDTLDQILSDDKERDTILLKRVILKKVVSETKDGEKLKVILRSWKSLQLPRKDVYKD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: : : .**: . * : *. .: . : . : .::* : * : :. ..:**** : ** ** ..:*:::**: *: *:*: .:* : ::*** **.***:*:*::**:***:.*:.***:**. :**** :** **.: ******** : .::** .* : *::**** .*..:.:* :*:** ****:**:* : * ", "identical_positions": 79, "similar_positions": 77, "identity": "32.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2931", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43490-1", "uniprot_id": "NAMPT_HUMAN", "id": "P43490-1", "name": "Nicotinamide phosphoribosyltransferase", "aln": "MNPAAEAEFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKTENSKLRKVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLN-IELEAAHH--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99KQ4-1", "uniprot_id": "NAMPT_MOUSE", "id": "Q99KQ4-1", "name": "Nicotinamide phosphoribosyltransferase", "aln": "MNAAAEAEFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKTENSKVRKVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKEVYREHFQDDVFNERGWNYILEKYDGHLPIEVKAVPEGSVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGIALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTEAPLIIRPDSGNPLDTVLKVLDILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKKWSIENVSFGSGGALLQKLTRDLLNCSFKCSYVVTNGLGVNVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGHDLLHTVFKNGKVTKSYSFDEVRKNAQLN-IEQDVAPH--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1RDZ8-1", "uniprot_id": "F1RDZ8_DANRE", "id": "F1RDZ8-1", "name": "Nicotinamide phosphoribosyltransferase", "aln": "--MMAAQDFNFLLATDSYKITHYKQYPPNINKVYSYFECRHKKG-------AQFSEVVFFGLQYLLKKYLTGPVITEEKIQEAKVFYQMHFKQAVFDEEGWRKVLEKYDGRLPIRIKAVPEGKIIPRGNVLFTVENTDADFFWLTNYIETMLVQMWYPITVATISREFKKILAKHLKATSGNLESLDLKLHDFGYRGVSSQESAALGGAAHLVNFCSTDTVAGLLMAQRYYG--CPMAGFSIPAAEHSTIISWGRSREKDAFECLLDQFPSGPVAVVSDSYDIFKACKHIWGDKLKERVMERSEDSALIIRPDSGDPAETLLEVIKILEECFGCSLNSVGYKVLPSYLRIIQGDGIDLNSINEILQKLSDEGWSAENVFFGCGSALLQKINRDTLNCAFKCSYVETCGKGMDVYKQPVTDPSKGSKRGRLSLRRNSDGFIETVERGAGKPEE---DMLVTVFENGTILQEYTLDEIRKAAQLREEDLSPSLHNREDGTTLDIHQKHIMNGVH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :**:********:********* .*********.** .::.*.**:****:*:***.* *:*:******* .*: **:: **:*.**. :******:***.:****** :**************.: :****:***:*** ******** *** ******:* *****:.*: **************:*.:*.:****** .******: : ::*** *:.*:*:******** :**:.:****** :: **.* **:********::**::***:.*:. ::.** ::.********:* :*:*:*:.** : * : ** ***:**.***:*****:*:*:::**:: :.:: ** **: **.*..****:.** ***:****** * * *::*:*:**:**.* **:*****:*.. * : *:*.* *. ** *:* ***:**.: :.*::**:** ***. : . : * ", "identical_positions": 291, "similar_positions": 129, "identity": "56.84%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2932", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9V399-1", "uniprot_id": "CP303_DROME", "id": "Q9V399-1", "name": "Probable cytochrome P450 303a1", "aln": "------------MFYTVIWIFCATLLAILFGGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYGFYGLKIGKDKVVIAYTNDAISEMMTN---EDIDGRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYE-PGSPEITQLLETFFELFKNIDMVGALFSHFPLLRFIAPNFSGYNGFVESHRSLYTFMSKEIELHR--LTYKNYDEPRDLMDSYLRAQDE--GNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQP-EIQERAFQEIKEVVGLERIPEWSRD--RTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSG-YEIPKDTMVIACFRGMLINPVDFPD-PESFNPDRYLFDG-HLKLPEAFNP-------FGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQ-VPEEVPLEGATAAVKPYDIMLVAREQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VW43-1", "uniprot_id": "CP305_DROME", "id": "Q9VW43-1", "name": "Probable cytochrome P450 305a1", "aln": "----------MSALIFLCAILIGFVIYSLISSARRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDFRS--DLVGLKLGREYVVVALGHEMVKEVQLQ---EVFEGRPDNFFLRLRTMGTRKGITCTDGQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQP------IEPVTWLAQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQFPWLRHVAPDRTGYNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRP-DVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGG-YDIPKNATILISLRSVHLDKEHWKD-PLEFRPERFIDSAGKCFKDEYFMP-------FGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGE-SPSMVLLPGITLTPKPYKVQFVKRT---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1NWJ8-1", "uniprot_id": "A0A8M1NWJ8_DANRE", "id": "A0A8M1NWJ8-1", "name": "", "aln": "MLAALLKLDLSSVGLSLFLGLIFLVLFEIFRIHSCKGRFPPGPTPLPFVGSIPHFLNNPMG----------FIKSLSQYGEMTTVYPGRKPAIILNTLQLMKEALVQN-GSSFSGRPPVPVFNWVTDG-YGIVMATFGHSWRQQRRFALHTLRNFGLGKKSVEERVTEESGYLISEFLKAEGKP------FNPQHAIHNAAANIICSIVFGDRFDYDNKSFTYLLEIIKENIIQAGSLVGQVFNLVPIIKHVP---GPHQKIYQNGQAFKSFIRESVKEHRQTLDPD---SPRDFIDAYLLEMEKQ-KSTQDSTFHEDNMVMAVGDLFLAGSDTTATTIRWGLIYLTQNP-DVQERCHEEIVRVLGFDRLPSMDDR---DRLPYTHATVHEFQRCANLVPTGVPHQTTQATKLRG-YDIPQGTQILINLTEILTNKEHWKH-PDTFNPENFLDDKGHFFKPEAFLP-------FSLGPRACLGETLAKAELFLFVTSLLQRIRFSWPTGEKLPDMNGIFGIVRSPKPFNIICHSRGSKH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P21595-1", "uniprot_id": "CP56_YEAST", "id": "P21595-1", "name": "Cytochrome P450-DIT2", "aln": "----------MELLKLLCLILFLTLSYVAFAIIVPPLNFPKNIPTIPFYVVFLPVIFPIDQT----ELYDLYIRESMEKYGAVKFFFGSRWNILVSRSEYLAQIFKDEDTFAKSGNQKKIPYSALAAYTGDNVISAYGAVWRNYRNAVTNGLQHFDDAP------IFKNAKILCTLIKNRLLEG---QTSIPMGPLSQRMALDNISQVALGFDFGALTHEKNAFHEHLIR---IKKQIFHPFFLTFPFLDVLP-----IPSRKKAFKDVVSFRELLVKRVQDELVNNYKFEQTTFAASDLIRAHN------NEIIDYKQLTDNIVIILVAGHENPQLLFNSSLYLLAKYSNEWQEKLRKEVNGITDPKGL---------ADLPLLNAFLFEVVRMYPPLSTIINRCTTKTCKLGAEIVIPKGVYVGYNNFGTSHDPKTWGTTADDFKPERWGSDIETIRKNWRMAKNRCAVTGFHGGRRACLGEKLALTEMRISLAEMLKQFRWSLDPEW---EEKLTPAGPLCPLNLKLKFNENIME-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : .** . * . : :. . . * :: : : : : .*. : : : * * : *. . :::.. . : :: * : : : . : : : * .: .: .* : :. : . * :: : * . : : * .. . : .: :::** :.. : : *. . : **: .:: : .* * * . : : :* . **:.. : : : . *.*:.: . : * * : *:*: *. : . :::.: . . . .: . ", "identical_positions": 32, "similar_positions": 116, "identity": "5.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2934", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P26045-1", "uniprot_id": "PTN3_HUMAN", "id": "P26045-1", "name": "Tyrosine-protein phosphatase non-receptor type 3", "aln": "MTSRLRALGGRINNIRTSELPKEK--TRSEVICSIHFLDGVVQTFKVTKQDTGQVLLDMVHNHLGVTEKEYFGLQHDDDSVDSPRWLEASKAIRKQLKGGFPCTLHFRVRFFIPDPNTLQQEQTRHLYFLQLKMDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESLHEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAKKLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHRVTKGGSTEDASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRRAVRSFADFKSEDELNQLFPEAIFPMCPE-GGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGN-EDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQMLDPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2ALK8-1", "uniprot_id": "PTN3_MOUSE", "id": "A2ALK8-1", "name": "Tyrosine-protein phosphatase non-receptor type 3", "aln": "MTSRLRALGGRINNTRTSELPKEK--TRSEVICSIRFLDGLVQTFKVNKQDLGQSLLDMAYGHLGVTEKEYFGLQHGDDPVDSPRWLEASKPLRKQLKGGFPCTLHFRVRYFIPDPNTLQQEQTRHLYFLQLKMDVCEGRLTCPLNSAVVLASYAVQSHFGDFNSSIHHPGYLADSQFIPDQNDDFLSKVESLHEQHSGLKQSEAESCYINIARTLDFYGVELHGGRDLHNLDLMIGIASAGIAVYRKYICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHSFFQAKKLLPQEKNVLSQYWTLGSRNPKKSVNNQYCKKVIGGMVWNPVMRRSLSVERLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGPLSPKDSDSEVSQNHSPHRESLSENNPAQSCLTQKSSSSVSPSSNAPGSCSPDGVDQRFLEDYHKVTKGGFVEDASQYYCDKSDDGDGYLVLIRITPDEEGRFGFNLKGGVDQKMPLVVSRINPESPADTCMPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRKAVRSLAEIRSEDELSQLFPEAMFPACPE-GGDSLEGSMELLKKGLESGTVLIQFEQLYRKKPGLAVSFAKLPQNLDKNRYKDVLPYDTTRVLLQGN-EDYINASYVNMEMPAANLVNKYIATQGPLPNTCAQFWQVVWDQKLSLVVMLTTLTERGRTKCHQYWPDPPDIMDHGIFHIQCQTEDCTIAYVSREMLVTNTETGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVKYVRSLRVDGEPALVHCSAGIGRTGVLVTMETAMCLIERNLPVYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQRLDPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QLN8-1", "uniprot_id": "F1QLN8_DANRE", "id": "F1QLN8-1", "name": "protein-tyrosine-phosphatase", "aln": "MTSPWCMLGNKITALGRADLSKHTHMPRSGLLCLVLFPDGTTQNFTVNKHDAGHLLFDLACEHLNIVEKQYFSMQISEDTSSSPRWLDPNKPFKKQLKGSPPFFLMFRVRFFISDPNSLQHEQTRHFYFLQIRKDICEGRLKCPLSSAVVLASYSVQSELGDYNPETPT-GYLSKTHFIPEQDQEFLLKVESLHPQHKGLSQSDAELCYLNTARTLDLYGVELHHAQDASNPAVWVGITSGGVALFCHLICSSFFPWINIIKISFKRKRFFVHLRRKHGELGHHVVSLSMPNSRACKNLWRSCVDHHTFYNRK----------------PSHSASKLSSIPLYRKLVGEQMLNPMVR-SSSVEQLETKSLPSRSPPNTPNWRSPRVRHDFRNPRPSSVDNLTNEMSYVTESEDVFYTYR----------------KPQEE-------------ERRSGSWSHGDDIT------------------------IEEDDLHVWDKSVTADGDLLLVRISPDQDGKFGFNVKGGVDQKMPLAISHVNLASPAGRCVPPLMEGDQVLLINGRDISEHTHQQVVMFIKASRESHSKELALLVRRKGVS--LRVEPTLQLGLTLPGEISPLSTHPSGETLEESMARLEKGLVTGTLLLHFEKLYRKKEGMLMSCAKQSENMDKNRYKDVLPYDITRVVLQEEGDDYINASHVKTEP--AGCVLQYIAAQGPLPHTCTHFWRSVWEQDVNVIIMLTTLTERGRTKCHQYWPHPPEVRDYGYLQVCCHSEECNLAYVTRQLTLTNTQSGQQRSITHLQYVAWPDHGVPEDSSDFLDFVKSVRSMRQESVPLMVHCSAGIGRTGVLITMETAMTLMEKEKPVYPLEVITLMREQRAMLVQTSCQFTFVCEAILRVYREKVKPNS---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** **.:*. ::*.*.. .** ::* : * ** .*.*.*.*:* *: *:*:. **.:.**:**.:* .:*. .*****:..*.::*****. * * ****:**.***:**:*****:****:: *:*****.***.********:***.:**:*.. ***:.::***:*:::** ****** **.**.**:** **:* *****:****** .:* * : :**:*.*:*:: : **:**:**:**:*******:**:* *:*:.* .*:*::.* * *:*****:***:**:*:: * *:...* . :*::* : ** :* * ***:************ ********:**::*:** **.***:***:*:**:*******: .*:.* :: *.* * ..: . *: . : **. .*. *:*:**:**::*:****:**********.:*::* ***. *:* * ****::************:**************:****::**:.* ... :*. :* : * ... .*::** ** *:*** :**:*::**:***** *: :: ** .:*:************ ***:** : :******:*: * *. * :***:*****:**::**: **:*.:.:::******************.**:: ::* ::: *::*:*.:***:*:: :***::*:::::**************:******:**: ***:* :. * :*************:****** * *:: *:***::: **:****:****.*:.**********.* : ", "identical_positions": 471, "similar_positions": 244, "identity": "51.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2939", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q00536-1", "uniprot_id": "CDK16_HUMAN", "id": "Q00536-1", "name": "Cyclin-dependent kinase 16", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MDRMKKIKRQLSMTLRGGRGIDK------------TNGAPEQIGLDESGGGGGSDPGE----------APTRAAPGELRSARGPLSSAP------EIVHEDLKMGSDGESDQASATSSDEVQSPVRVR-----MRNHPPRKISTEDINKRLSLPADIRLPEGYLEKLTLNSP-----IFDKPLSRRLRRVSLSEIGFGKLET-----------YIKLDKLGEGTYATVYKGKS--------------KLTDNLVALKEIRLEHEEGAPCTAIREVSLLKD-------------------------------------LKHANIVTLHDIIHTEKSLT-------LVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRG----------LAYCHRQKVLHRDLK---------PQNLLINE-------RGELKLADFGLARAKSIPTKTYSN-------------EVVTLWYRPPDILLGSTDYS-----------TQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILG--TPTEETWPGILSNEEFKTYNYP-----KYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMK---HPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDS---GRPAFRVVDTEF------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04735-1", "uniprot_id": "CDK16_MOUSE", "id": "Q04735-1", "name": "Cyclin-dependent kinase 16", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MDRMKKIKRQLSMTLRGGRGIDK------------TNGVPEQIGLDESGGGGGSDLGE----------APTRIAPGELRSVRGPLSSAP------EIVHEDMKMGSDGESDQASATSSDEVQSPVRVR-----MRNHPPRKISTEDINKRLSLPADIRLPEGYLEKLTLNSP-----IFDKPLSRRLRRVSLSEIGFGKLET-----------YIKLDKLGEGTYATVYKGKS--------------KLTDNLVALKEIRLEHEEGAPCTAIREVSLLKD-------------------------------------LKHANIVTLHDIIHTEKSLT-------LVFEYLDKDLKQYLDDCGNVINMHNVKLFLFQLLRG----------LAYCHRQKVLHRDLK---------PQNLLINE-------RGELKLADFGLARAKSIPTKTYSN-------------EVVTLWYRPPDILLGSTDYS-----------TQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILG--TPTEETWPGILSNEEFRTYNYP-----KYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDARK---HPFFLSLGERIHKLPDTTSIFALKEVQLQKEANIRSTSMPDS---GRPAFRVVDTEF------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9Q3R1-1", "uniprot_id": "A0A8M9Q3R1_DANRE", "id": "A0A8M9Q3R1-1", "name": "cyclin-dependent kinase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MDRMRKIKRQLSLTLRGGNSGDKSLSETISSQDTGAHSDSEAMPVGGSGGLRGSVRGSGGSFSMHSLLQSYSSALRRPRSLGRSLSSYLNHTTRLEIVHEDVKMGSDGESDQASATSSDEVHSPVRVR-----LRNNPGRKISTEDINKRLSLPADIRLPDGYLEKFSLNSP-----LFDKPLSRRLRRVSLSEIGFGKLET-----------YVKLDKLGEGTYATVYKGRS--------------KLTDNLVALKEIRLEHEEGAPCTAIREVSLLKD-------------------------------------LKHANIVTLHDIIHTQKSLT-------LVFEYLDKDLKQYLDDCGNSIHMHNVKLFLFQLLRG----------LNYCHRRKVLHRDLK---------PQNLLIND-------RGELKLADFGLARAKSIPTKTYSN-------------EVVTLWYRPPDILLGSTDYS-----------TQIDMWGVGCIFYEMSTGRPLFPGSTVEEELHFIFKLLG--TPTEETWPGITSNEEFISYNYP-----RYRADCLHNHTPRLDNDGVELLSKLLQFEGKKRIAAEEAMR---HPYFHCLGERLLTLPDTTSIFALQEIQLEKEPGMRTNSLSESEL-LQRCLRFRHTLVNSISQRQSLLF-------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5D006-1", "uniprot_id": "UBP11_RAT", "id": "Q5D006-1", "name": "Ubiquitin carboxyl-terminal hydrolase 11", "aln": "MAAVAADPAAAAVPASAEDRETQPEAMPDLDQQWRQIGNGRERPLRAGESWFLVEKHWYKQWEAYVKGGDQDASTFPGSINNSGLFEDQISWHLRERLVEGDDYVLLPAPAWNYLVSWYGLKDDQPPIERKVIELPGIRKVEVYPIELLLVQHSDMETALTIQFSYSDSVDLVLQTAR--EQFLVEPQEDTRLWTKNSEGSLDRLCNTQITLLDACLETGQLVIMETRNKDGTWPSAQLCGMNNMPDEDEDFQGQPGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNRYLEELNFRNPLGMKGELAEAYADLVKQTWSGYHRSIVPNVFKNKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVELCNGAGRPDLEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPLPVCSRRVLEVFFVPMDPRRKPEQHRVVVPKKGNISDLCVALSTHTSVAPDKMIVADVFSHRFYKLYQLEDPLSGILDRDDIFVYEVTGRIEPVEGSRDDIVVPVYLRERTPSRDYNNSYYGLILFGHPLLVSVPRDRFSWEGLYNILMYRLSRYVTKPTSDDDDGDEKGDENEDEDVEDDSSSEEEKEEMSGPTDNDGTQESEQEQAGTSSGVTGRCPSLLDNSLHTSQWPPRRRRKQLFTLQTVNSNGTSDRTTSPEEAQTQPYIAMDWEPEMKRRYYDEVEAEGYVKHDCVGYMLKKNPVQLKECIKLFTTVETLEKENPWYCSSCKQHQLATKKLDLWMLPEVLIIHLKRFSFSKFSREKLDTLVQFPIRDLDFSEFVIKPKNESAPDLYKYDLIAVSNHYGGMRDGHYTTFACNKDSGQWHYFDDNSVSPVNENQIESKAAYVLFYQRQDVGRRQSQTASSETPTSPASSSTPNSDIMDVN", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .:: *:: : . . * .. : .. . . . . . *. . .* .:: *. * .. :. .: ::*.:: : : .: *::* * .* . .*.:.* : .. . . :. : :..:: :.: . :*: : :: : .*::: : *. : :* . * :: * :. :: .:. *. :**: * *:.** * : *..*:: **.: .* * * .. :. .:: :: . : *.:. ** : : **:. .* :: : *:* : **. .: * : . : : *.** . *. .: * : : : . :* .::*. : : . *. . * * ..: : : :: :* : . : * * * .: :*:: :: : :*:: . :: ... .:: * *: : : : ..:. . : . . . ", "identical_positions": 63, "similar_positions": 198, "identity": "6.83%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-294", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RKJ1-1", "uniprot_id": "MAEA_RAT", "id": "Q5RKJ1-1", "name": "E3 ubiquitin-protein transferase MAEA", "aln": "MAVQESAAQLSMTLKVQEYP-TLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSS--CPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAAS---------------MWKRKRMDRMMVEHLLRCG----------YYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERRE-TATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELVRQNKRLDAVRHARKHFSQAEGSQLDEVRQVMGMLAFP-------PDTHISP---------------------------------------------------------YKDLLDPARWRMLIQQFRYDNYRLHQLGNSSVFTLTLQAGLSAIKTPQCYK----EDGSS-----------------------KSPDCPVCSRSLNKLAQPLPMAHCANSRLVCK-ISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVVCPRTKEVFHFSQAEKVYIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4VC33-1", "uniprot_id": "MAEA_MOUSE", "id": "Q4VC33-1", "name": "E3 ubiquitin-protein transferase MAEA", "aln": "MAVQESAAQLSMTLKVQEYP-TLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSS--CPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAAS---------------MWKRKRMDRMMVEHLLRCG----------YYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERRE-TATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELVRQNKRLDAVRHARKHFSQAEGSQLDEVRQVMGMLAFP-------PDTHISP---------------------------------------------------------YKDLLDPARWRMLIQQFRYDNYRLHQLGNSSVFTLTLQAGLSAIKTPQCYK----EDGSS-----------------------KSPDCPVCSRSLNKLAQPLPMAHCANSRLVCK-ISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVVCPRTKEVFHFSQAEKVYIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L5Y9-1", "uniprot_id": "MAEA_HUMAN", "id": "Q7L5Y9-1", "name": "E3 ubiquitin-protein transferase MAEA", "aln": "MAVQESAAQLSMTLKVQEYP-TLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSG--CPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAAS---------------VWKRKRMDRMMVEHLLRCG----------YYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERRE-TATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELIRQNKRLDAVRHARKHFSQAEGSQLDEVRQAMGMLAFP-------PDTHISP---------------------------------------------------------YKDLLDPARWRMLIQQFRYDNYRLHQLGNNSVFTLTLQAGLSAIKTPQCYK----EDGSS-----------------------KSPDCPVCSRSLNKLAQPLPMAHCANSRLVCK-ISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVVCPRTKEVFHFSQAEKVYIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXR3-1", "uniprot_id": "MAEA_DANRE", "id": "Q7SXR3-1", "name": "E3 ubiquitin-protein transferase MAEA", "aln": "MAVQETAAQLSMALKVQEYP-TLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSS--FPVVDTVVSLLDGVVEKLSALKRKAAESIQAEDESAKLCKRRIEHLKEHSSDQPASVN---------------VWKKKRMDRMMVEHLLRCG----------YYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERQE-TATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELIRQNKRMDAVRHARKHFSQAEGGQLDEVRQVMGMLAFP-------SDTHISP---------------------------------------------------------YKDLLDPARWKMLIQQFRYDNYRLHQLGNNSVFTITLQAGLSAIKTPQCYK----EDGTS-----------------------KNPDCPVCSKSLNKLAQPLPMAHCANSRLVCK-ISGEVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVICPRTKEVFNFSQAEKVYIM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40492-1", "uniprot_id": "FYV10_YEAST", "id": "P40492-1", "name": "GID complex subunit 9", "aln": "MAEKSIFNEPDVDFHLKLNQQLFHIPYELLSKRIKHTQAVINKETKSLHEHTAALNQIFEHNDVEHDELALAKITEMIRKVDHIERFLNTQIKSYCQILNRIKKRLEFFHELKDIKSQNSGTSHNGNNEGTRTKLIQWYQSYTNILIGDYLTRNNPIKYNSETKDHWNSGVVFLKQSQLDDLIDYDVLLEANRISTSLLHERNLLPLISWINENKKTLTKKSSILEFQARLQEYIELLKVDNYTDAIVCFQRFLLPFVKSNFTDLKLASGLLIFIKYCNDQKPTSSTSSGFDTEEIKSQSLPMKKDRIFQHFFHKSLPRITSKPAVNTTDYDKSSLINLQSGDFERYLNLLDDQRWSVLNDLFLSDFYSMYGISQNDPLLIYLSLGISSLKTRDCLHPSDDENGNQETETATTAEKEVEDLQLFTLHSLKRKNCPVCSETFKPITQALPFAHHIQSQLFENPILLPNGNVYDSKKLKKLAKTLKKQNLISLNPG-QIMDPVDMKIFCESDSIKMYPT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :. : .: :::: :::*** *.**:: :* *::**. : .* *:: :. : .:: : ::.*:. ::* .*:: : : *:*:*.::* .. :. . * :. : :: ::* * . ::*:.* : :** ::**:: :::* *:.:. ** :.. . ::* ::**. * * .* ***. *:**:***:: :: **: ::.: .:: ::: . *:* * . : *. * :*** ** :* : * * * :: :.:.. : : *. *:*::** :* : *:*.. * :*****.::: ::*.**:** :*:*. : * * :. : . . :.*:*:. . ::: * ::* *:: *:* ", "identical_positions": 95, "similar_positions": 163, "identity": "18.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2941", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C341-1", "uniprot_id": "SUCO_MOUSE", "id": "Q8C341-1", "name": "SUN domain-containing ossification factor", "aln": "MKKYRRALALVSCLSLCSLVWLPSWHVCCKESSSASTS-YYSQDDNCAIGSEDTQFQKKNEREEPSN--------AELSGKSNSYLTISPEGNKIKDDYTVDVQDLETT-----KLSLPVVEALPTVDLHEE--SSSVVVGSETIENSSSSSTSERTPVSELDEVEKSGTLSIAKPGE--VEQPEADCDAGEAPDADAPVEQ---------PAFVSPPESLVG--------QHIENVSS-----------SHGKEKVTKSEFESKVSVSEQDG-----GDPKSALNTSDTLKNESSDYTKPGETD--PTSVTS--------PKDP-----EDIPTFDEWKKKVMEVEKEKSQSLHPSSNGGPHATKKVQKN-RNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQVKQFDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERNVQSFPLDEQMYAKYVKMFIKYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYQSERQELFDEDYDYPLDYNTVEDKSSKNLLGSATNAILNMVN-IAANILGAKT--EDLTEGNKSISENATATTEPKMTESTRVSTPVPSPEYVIKEVHTHD-------REPSTSDPPKESPIVQLVQE--------EEEEASPSTVTLLGS-GEQEDESSSWFESETHILCSELTSICCISSFSEYIYKWCSVRIALYRQR------------SRT-VSKGKD-FVPPQPSLLLPVESVEVSVPQPPSGDVDSENMEREAETVDLDDLSS-VHQGHLINHTVDTIELEPSYPQTLSQSLLLDVTPEMNSLSKVEGSESVKSEGGYIPSQLMTQESSVEFDDKTEKKTESFSSAEKLSVIYETSKVN----EVMDNTVKEDILSTEVVTKFPETVVPPPMNTATVPEGESVETKPSIADTLKHTVTPVMDP-SLPEVKEDEQSPEDALLRGLQRTATDFYAELQNSTDLGYGNGN----LVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIHLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVMSLVLCVVLGLMLCMQRCRTTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLIRSKSLQFTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKT-EKIETIKPADPLHPIANGDIKGRK-PFTNQRDFSNMGEVYHSSYKGPPSEGSSE--TSSQSEESYFCGISAC---TSLCNGQTQKTKTEKRALKRRRSKVQDQGKLIKALIQTKSGSLPSLHDIIKGNKEITVGAFGVTAVSGHI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBS9-1", "uniprot_id": "SUCO_HUMAN", "id": "Q9UBS9-1", "name": "SUN domain-containing ossification factor", "aln": "MKKHRRALALVSCLFLCSLVWLPSWRVCCKESSSASASSYYSQDDNCALENEDVQFQKKDEREGPIN--------AESLGKSGSNLPISPKEHKLKDDSIVDVQNTESK-----KLSPPVVETLPTVDLHEE--SSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSE--TEQSETDCDVGEALDASAPIEQ---------PSFVSPPDSLVG--------QHIENVSS-----------SHGKGKITKSEFESKVSASEQGG-----GDPKSALNASDNLKNESSDYTKPGDID--PTSVAS--------PKDP-----EDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHATKKVQKN-RNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQVKQLDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERNVQSFPLDEQMYAKYVKMFIKYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYHSERQELFDEDYDYPLDYNTGEDKSSKNLLGSATNAILNMVN-IAANILGAKT--EDLTEGNKSISENATATAAPKMPESTPVSTPVPSPEYVTTEVHTHD-------MEPSTPDTPKESPIVQLVQE--------EEEEASPSTVTLLGS-GEQEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVALYRQR------------SRTALSKGKDYLVLAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVELEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQKSESFSSIEKPSITYETNKVN----ELMDNIIKEDVNSMQIFTKLSETIVPP-INTATVPDNEDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYANGN----LVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVISLVLCVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLMRSKSLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKI-EKIETIKPEEPLHPIANGDIKGRK-PFTNQRDFSNMGEVYHSSYKGPPSEGSSE--TSSQSEESYFCGISAC---TSLCNGQSQKTKTEKRALKRRRSKVQDQGKLIKTLIQTKSGSLPSLHDIIKGNKEITVGTFGVTAVSGHI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IAV9-1", "uniprot_id": "A0A0R4IAV9_DANRE", "id": "A0A0R4IAV9-1", "name": "SUN domain-containing ossification factor", "aln": "MKKLR---VLFLCSVLALLCWHSCHDVYCSEEVSSGPGLPAQDDGSYTMQEPGAGEKVEEERATHTQSSYDVGLETERAALKETSLHSQETPHEEKHKQTVNLEEVLEEPQIQHDSALPELEQQQQQEQHPEGQSSQHPDQQDSAQPPTFAQPETAPPLSQPDPEVPQATATEDQAAQPSTDETPPHPDPHAEEDASAPADELQNSPESTSPTSVTSSESLSSGLDVPRPDAAVENSSASQCEVGSVPPFSQQLGTTLTSVVEEQVETQAENQSTVLEQSTETSTDPADSLDPSELDLTETGQTDRIPPPTESQQVADHEGATDPPVPSKEDIPTFDEWKKKVMEVEEKKSQSLHTSSNGSPHPVKKVQKNFKNNYASVECGAKILSANNEAKSTSAILMENMDLYMLNPCSTKIWFVIELCEPIQVKQLDIANFELFSSTPRDFLVSISDRYPTNKWIKLGTFHARDERTVQSFPLDEQLYAKYVKMFIRYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYDEIADSQYTSERAEYLDEDYDYPPGYLPSEDKASKNLLGSATNAILNMVNNIAANVLGGKPELEDGAELEGNVSS-GTENVTQASTETTLTPDPTPTEQPHTLDVLELDPTFVKEDMEAPIPEAPSQAPTVAPAEESRIVILIEEDEESTQPTVTLLEEEGEEERRLEELWESESTTYCGHLSTLSCLASLHEHFYCYCSAALALQRQRKDRRHKAQHTQAHTKTQTTSQQTLTDPTPSQEPPAPSEKLSEAERPS-QTQSERISPTETAAAPSESSNWESSSTELELPPETILLEPSRTSTLPP-HSFSETPTQNIPESLPTGEPVDQRPQYLVDIPETHAPGSVCSSTSSVPSPSAVSSTPLSSTTEPHSLETDPPKLELPVPTKEQTAQPLPTHTRPAEIPPPTEIPILIPEASENGKVSLVEDQHHN--AVVSQPELSEAP-HEDTVDDILLP--HRTAGEFYAEQQQTAEMGHSNGNGNGNQVHGSNQKESVFMRLNNRIKALEMNMSLSSRYLEELSQRYRKQMEEMQRAFNKTIIKLQNTSRIAEEQDQKQTESIQMLQSQLENATRIMLNLSATVAQLQREVSDRQIYLVLSLILCLMLGLLLCTQCCRSSTNHN--TSPTIPMSNNYPSPKRCFSSYDDMSLKRRVSCPLVRSKSFQLPTSEVGPDDLYIVEPLRFSPEKKKKRCKTKAGERVETLR-ASATAPNGLLKLNGESSPPLQFLPSTCNGYTSTCSSRDCASEGSSESSVSTLSEESFGSAPSVNGHELVLYNGEPPPACPPAKSRTEKKRRRSRQG--EQDSMLSASLPLPALEELIKGKTELGVASFGRTAVTGRV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** * .*. * *. * * .. * *.*. *:... .:*.. :: . .. : ::** : :* . . : * . :: *.. *:::: . : * :* : * * **. .:: : : :... .*:*: * ..* . :..: .::. .. * **.** :: *: *:..:** . :** *: *: . .* .*.:*... :. ..::: :.:*.*. .. * *:.*: * *... * ..** *****************::****:*.****..*..****** :*************:** *********:*****************************:****:*******:**********************.****.*********:*********:********************************:******* *** * :******* .* . ***:***************** ****:**.*. ** :* : .:*. .* .. .*:* .. *.*: : :* * *.. .:.*.::* * .:* *:**:: .***** . **:* . . :***: *..*:::.*::*: *::* :**. :** *** . :..:: :. . *. *. * .:* : * : :. .:. :. .: *. .. :: . ::: **** ..**. :. ** * .: .*.*. . :: . .: .. .. :. : * * * *. .:: :: .:: : : *: : :** : . : . : * .:.: ::. .*:. .*.*. .*:: :* ** :*** :**** *:::::*:.*** **********************:*****.******************:******:**************:***:*::**:** * *::: *******:*:******* ***:**:**::***:** * **.:::.: ..:* **:**************.****.* **:****:*:. .**.*:********:*********** * *::**:: .. * . .::*.. * : : * . .* :. .****** .*: ****: .. *. * **:. : . :: ..:: : . ** : : : * .**:*.::***:.*: *.:** ***:*::", "identical_positions": 559, "similar_positions": 378, "identity": "40.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2957", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PCX9-1", "uniprot_id": "TRI37_MOUSE", "id": "Q6PCX9-1", "name": "E3 ubiquitin-protein ligase TRIM37", "aln": "MDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCSLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRRRLMELISLVQEVERNVEAVRNAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSSEILMMFQQVHRKPMASFVTTPVPPDFTSELVPSYDSATFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAGLPETSKYEYRVEMVHQSCNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNRQNDTVILRFQVRSPTFFQKCRDQHWYITQLEAAQTGYIQQINNLKERLTIELSRTQKSRDLSPPDNHLSPQNDDSPETRTKKAGSCSDMLLEGGPTCASVRETKEDEDEEEKIQNEDYHHELSDGDLDLD-LVGEDEVNHLDGSSSSASSTATSNTEENDIDEETMSGENDVEYN-SMELEEGELMEDAAAAGPPGSSHSYVGASSRMSRRTHLCSAATSSLLDIDPLILIHLLDLKDRSSMENLWGLQPRPSASLLQPTASYSRKDKD-QRKQQAMWRVPSDLKMLKRLKTQMAEVRCMKTDVKTTLSDIKGSSVASTDMQTNLFCADQAALTTCGPENSGRLQDLGMELLAKSSVAGCYIRNPTNKK-NSPKSAR-AIAGSLSLRRAVDSGENSRSKGDCQVLAEGSS-------GSSQSGSRHSSPRALTHGIIG-DLLPKSEDRQCKALDSDAVVVAVFNGLPTVEKRRKMVTLGTNAKGGRLEGMQMADLESHSEAGEVQPTLPEG---ASAAPEEG------------MSSDSDIECDTENEEQEEHTSMGAFNDPFLAQ--PPDEDSHSSFPDGEQIDPENLHFNPDEGGGR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94972-1", "uniprot_id": "TRI37_HUMAN", "id": "O94972-1", "name": "E3 ubiquitin-protein ligase TRIM37", "aln": "MDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCSLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRRRLMELISLVQEVERNVEAVRNAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSSEILMMFQQVHRKPMASFVTTPVPPDFTSELVPSYDSATFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAGLPETSKYEYRVEMVHQSCNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNPQNDTVILRFQVRSPTFFQKSRDQHWYITQLEAAQTSYIQQINNLKERLTIELSRTQKSRDLSPPDNHLSPQNDDALETRAKKS-ACSDMLLEGGPTTASVREAKEDEEDEEKIQNEDYHHELSDGDLDLD-LVYEDEVNQLDGSSSSASSTATSNTEENDIDEETMSGENDVEYN-NMELEEGELMEDAAAAGPAGSSHGYVGSSSRISRRTHLCSAATSSLLDIDPLILIHLLDLKDRSSIENLWGLQPRPPASLLQPTASYSRKDKD-QRKQQAMWRVPSDLKMLKRLKTQMAEVRCMKTDVKNTLSEIKSSSAASGDMQTSLFSADQAALAACGTENSGRLQDLGMELLAKSSVANCYIRNSTNKKSNSPKPARSSVAGSLSLRRAVDPGENSRSKGDCQTLSEGSP-------GSSQSGSRHSSPRALIHGSIG-DILPKTEDRQCKALDSDAVVVAVFSGLPAVEKRRKMVTLGANAKGGHLEGLQMTDLENNSETGELQPVLPEG---ASAAPEEG------------MSSDSDIECDTENEEQEEHTSVGGFHDSFMVMTQPPDEDTHSSFPDGEQIGPEDLSFNTDENSGR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B767-1", "uniprot_id": "A0ACD6B767_DANRE", "id": "A0ACD6B767-1", "name": "", "aln": "MDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCNLTKHEENDKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRHRLMELISLVQEVEKNVEAVRGAKDERVREIRNAVEMMIARLDNQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSPEILLMFQQVHRKPMQSFVTTPVPPDFTSELVPAYDSSTFVLANFSTLRQRADPVYSPPLQISGLCWRLKVYPDGNGVVRGNYLSVFLELSAGLPETSKYEYRVEMVHQASSDPTKNIIREFASDFEVGECWGYNRFFRLDLLASEGYLNMQTDTLVLRYQVRSPTFFQKCRDQYWYITQLESAQSSYIQQINNLKERLAIELFRRQKSRSSSPPDRRLCPTTSSGRDSRQGKS-----SVLEECSQAASV-ETKEDED-EEKTQHDD-SNELSDGDLEVDCLTGDEDVNPLDGSSTSGSSTATSNTEENDIDEETMSGENDVEYSRNLELEEGELADDVAGAAG-GS-----GAGVRGSRRG--AGASSASLLEIDPVILIQLLDLKDRSHVESLWGMQPRPPTSLLQTQAAAVPSRKERERRPQAVRRSAPDSGVLIRLKAQMAEVRSKMSDVKGQLEARSGATRVS-SHGASIHEQGPSMDSELGPSRKP------SELLFKAPISSRHTR-SGGKKSGSPKQESVGALGVLSLRRTVDAGEKELRGAGRESPTEPATTGPSSLDGSLKARSVQSSPPSLGSSSSSSDKASGSKHEDLLYGASDLFSISALNGASAPATKQHRATAIG--PGLLTDSSLTCDLESAGEIHQSLLSLAEPSSSSSSHPDEGVLSQKPHHVLPSMSSDSELDCDTENENEDEVVPLEAGDT--------SAFDTRTLPCTGEQLIPDDLSFTAEESTER", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********************************************************************************.*******:************************************************************:*************:******.*********************.**********************************************.***:********** *****************:***:**** ******************:******************* ***************************:..********************************.***** *.**::**:**********.***:*******:**:.************:*** * ****. ****.:*.* .... ::* *: :** . *** *:****: *** *::* :*******::* *. :::** *****:*.**************************. .:******* :*.*.*. ** *:. * *** ..*:::***:***:***:******** :*.***:****.:****. *: . *: :*: **: * ..* :* ***:******. :*** *. ..:: .* . :.:. . : : *.... *** *:.::. : * . .** .*** . * *****:**.**:. .. : :* :. ** :: * :*** :* . . * . ::..: ** . ::.:.* .: .::: .* * :. ***. .* : *.* :*: *:** *****:::******:::* ..: . . . *::: ***: *::* *..:*. *", "identical_positions": 621, "similar_positions": 180, "identity": "62.66%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2958", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJQ6-1", "uniprot_id": "CSTF1_RAT", "id": "Q5BJQ6-1", "name": "Cleavage stimulation factor subunit 1", "aln": "----MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMENDDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNPSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAVFNHTEDYILLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFRARFWYRRSTTD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LC2-1", "uniprot_id": "CSTF1_MOUSE", "id": "Q99LC2-1", "name": "Cleavage stimulation factor subunit 1", "aln": "----MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMENDDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNPSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAVFNHTEDYILLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFRARFWYRRSTTD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05048-1", "uniprot_id": "CSTF1_HUMAN", "id": "Q05048-1", "name": "Cleavage stimulation factor subunit 1", "aln": "----MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMENDDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAVFNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFRARFWYRRSTTD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QFK9-1", "uniprot_id": "F1QFK9_DANRE", "id": "F1QFK9-1", "name": "Cleavage stimulation factor subunit 1", "aln": "----MFRPKPTLKDRQHLYKLIISQLLYDGYTIIANSLISEVKPQNVVSPSEQLMQLAKIGMENDDSAVQYAIGRSDTVAPGVGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPLEVMMNETAQQNMENHPVIRTLYDHVDEVTCLSFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKHVQEAEMLRSISFHPSGDFLLVGTQHPTLRLYDVNTFQCFVSCNPLDQHTDTICGVCYNPSANSYVTCSKDGSIKLWDGVSNRCVTTFDKAHEGAEVCSAVFSKNSKYILSTGKDSVAKLWEISTGRTLVKYTGAGLSGRQTHRTQGVFNHTEDYVLLPDERTISLCCWDSRTAERKNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFRARFWYRRTTTD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V9V0-1", "uniprot_id": "Q9V9V0_DROME", "id": "Q9V9V0-1", "name": "Cleavage stimulation factor subunit 1", "aln": "MRDEILDPSNLVKNREILYRLMISQLMYDGLEKFAMELSMLVK-ADQCAPSERLLHVMIAGMQ---TLSDKDKTNSDDVLP--GIDLEFEPEASALAPEPHSYETAYVTSHKQACRAGAFSCDGSLVATGSVDASIKILDVERMLAKSAP--EDIEPGREQQ---GHPVIRTLYDHTDEVSYLEFHPKEHILASASRDGTVKLFDIAKPSVKKAHKVFTDCEPVLCLSFHPTGDYVAIGTEHNVLRVYDVATTQCFVSAIPSQQHKAGVTCVKYSPTGKLYATGSYDGDIKIWDGISGRCINTIAEAHGGAAICSLEFTRNGKYLLSSGMDSLVYLWELCTSRPIQTYTGAGTTGKQEHQTEAVFNHTEDYVLFPDEATTSLCSWNSRNGCRLTLNSLGHNGPVRYITHSPNGPAFLTCSDDFRARFWYRRANNQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. :*:*: **:*:****:*** :* * :* . :***:*::: **: : : .** * * ******:.:..:::**. .***.****** .**..::* **.*:****.********.******** * : ** .**********.***: * ***.*:****.*** *:**** :***.*:*.* . :.* : .:****:**:: :**:* .**:**: * *****. * :**. : * *..:.: *.* * ** **:***:*.**:.*: :** ** :** *::*.**:**:* **:. ***:.*.*.: ***** :*:* *:*:.********:*:*** * ***.*:**.. * .* *****. ** *.***..*.*:**************:..:", "identical_positions": 223, "similar_positions": 119, "identity": "51.26%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-296", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZGM8-1", "uniprot_id": "D3ZGM8_RAT", "id": "D3ZGM8-1", "name": "", "aln": "------------MSEESDSVRTSPSVASLSENELPPPPPEPPGYVCSLTEDLVTKAREELQEKPEWRLRDVQALRDMVRKEYPYLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHGCRRSWPEVFSNLRPSALKDVLNSG-FLTVLPHTDPRGCHVLCIRPDR-WIPSNYPITENIRAIYLTLEKLIQSEETQVNGVVILADYKGVSLSKASHFGPFIARKVIGILQDGFPIRIKAVHIVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLSSLHTSLPRNILPKEYGGTAGELDTASWNAVLLASEDDFVKEFCQPESGCDGLLGQPLLPEGLISDAQCDDSMRAMKSQLYSCY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D3D0-1", "uniprot_id": "TTPAL_MOUSE", "id": "Q9D3D0-1", "name": "Alpha-tocopherol transfer protein-like", "aln": "------------MSEESDSLRTSPSVASLSENELPLPPPDPPGYVCSLTEDLVTKAREELQEKPEWRLRDVQALRDMVRKEYPYLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHGCRRSWPEVFSNLRPSALKDVLNSG-FLTVLPHTDPRGCHVLCIRPDR-WIPSNYPITENIRAVYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFGPFIAKKVIGILQDGFPIRIKAVHIVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLPRNILPKEYGGTAGELDTASWNAVLLASEEDFVKEFCQPMPACDNLLGQPLLPEGLISDAQCDDSMRAMKSQLYSCY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BTX7-1", "uniprot_id": "TTPAL_HUMAN", "id": "Q9BTX7-1", "name": "Alpha-tocopherol transfer protein-like", "aln": "------------MSEESDSLRTSPSVASLSENELP-PPPEPPGYVCSLTEDLVTKAREELQEKPEWRLRDVQALRDMVRKEYPNLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHSCRRSWPEVFNNLKPSALKDVLASG-FLTVLPHTDPRGCHVVCIRPDR-WIPSNYPITENIRAIYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFGPFIAKKVIGILQDGFPIRIKAVHVVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLPRSILPKEYGGTAGELDTATWNAVLLASEDDFVKEFCQPVPACDSILGQTLLPEGLTSDAQCDDSLRAVKSQLYSCY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QZD8-1", "uniprot_id": "F1QZD8_DANRE", "id": "F1QZD8-1", "name": "", "aln": "------------MADQNGHIDLGPPRDTAAG--LGFPGPPPPIYTCTLTPELVAKAREELQEKPEWRLRDVQALRDMILKDHPNLRTRLDDAFLLRFLRARKFDYDRALQLLLNYHASRRAWPEVFQDLKPSTVKHVLDLG-FLTVLPRPDPQGRYILCLRPGK-WKPNDYPFVDNIRAIYLTLEKLIQPEETQVNGVVILVDYAGVGLSQASNPGPLLAKKVVGILQDGFPIRIKAVNIINEPRIFKGIFAIIKPFLKEKMAERYVLHGSDLASLHRVIPQSVLPQEYGGVSGRLDMSAWSRTLLEAEEEFVVEFCQPDPLEGVIMPDALLFEGEQGGAHGEDSFRHLRSQLYYCY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VM11-1", "uniprot_id": "Q9VM11_DROME", "id": "Q9VM11-1", "name": "CRAL-TRIO domain-containing protein", "aln": "------MGKAECIS-----------YDEHKLPYIDLGSAQIRMEKEQAPEWALKKAQDELREVPGVKEQAIKELRELIQNEKYLNLP-LDDEYMMMFLRPTHYYPESALKRLKNFYHMKLKYGAACENIIPSKLRNVFEAN-ILNLLPQRDQHGRRLLVLEAGKKWKPSQVPLVDLFRGIQLTVLGSMVEPYSQICGSVVIIDMEGLPLSHITQFTPSFAAMLLDYIQECICMRLKAVHIVNNSYIFNMLFAVFKPFIREKLRKRIFFHGKDYKSLISHIEAKALPPKYGGSATWELPHGKVLGEFFECYSKDYELADSYGYTEGYKMKK---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VIW5-1", "uniprot_id": "Q9VIW5_DROME", "id": "Q9VIW5-1", "name": "CRAL-TRIO domain-containing protein", "aln": "MTMLTTASAMRCLPSEFPLGVPTMLSDIDQLPTLQVGDYTLQFELGEPTAQGKEVAIKELRETPERQKEASKELARLLEAETDLLYPKGNEEWLIRYLRPCKYYPESARDLIKRYYAFKVKHADVYTDLKPSNEANIFKHN-ILTVFPNRDQLGRRILVLELGKRWKHKQVTLDEVFKGAVLFLEAAMLEPETQICGAVVIFDMDGLSLQQTWQFTPPFAKRIVDWLQDSVPLRIKAIHIVNQPKIFQVVFALFKPFLKEKLRSRIIFHGTDRESLHKYMSPKCLPAAYGGFREASRIDSDQWYQLLLKCDTEFDTINSYGYKKK--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VM12-1", "uniprot_id": "Q9VM12_DROME", "id": "Q9VM12-1", "name": "CRAL-TRIO domain-containing protein", "aln": "------------------------------MAATDIAEEAFHLRLGYLKPETVEIARVELRETEEVKAEAIIKLRELLKATPELNYK-DDDAFLTVFLRACHFYPEGALEKMKTTASFRKEYASLVRGLLVEQVKEKFVKGSVINVLKNCDQKGRRVLIVNCGKLWDPSDITSDEMFRMLYMVHLAAQLEEETQVRGVVCIMDFEGLSMKQVKALSPSFSKRLLTFIQEAMPLRMKEVHFVKQPFIFNMVWSLFKPFVKQKLNNRMHFHGSDMKSLQKFLDPSVLPANYKGTLPAIDYGGVEWFPALEQQAQYVEEWSQLGPAQW--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **:* : . * :: :: :: :**. :: : * . : : .: . . : . .:.:: . * * :: :. .: * .: . : :: : :*: * * : * *: :.: * :: :: :*: . :*:* ::.:::. **: :::::***:::*: .* :**.* ** : . ** * * : . ", "identical_positions": 36, "similar_positions": 82, "identity": "10.08%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2963", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUD1-1", "uniprot_id": "CHIP_MOUSE", "id": "Q9WUD1-1", "name": "E3 ubiquitin-protein ligase CHIP", "aln": "MKGKEEKEGGARLGTGGGGSPDKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQPEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDDIPSALRIAKKKRWNSIEERRIHQESELHSYLTRLIAAERERELEECQRNHEGHEDDGHIRAQQACIEAKHDKYMADMDELFSQVDEKRKKRDIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLAMKEVIDAFISENGWVEDY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6HD62-1", "uniprot_id": "CHIP_RAT", "id": "A6HD62-1", "name": "E3 ubiquitin-protein ligase CHIP", "aln": "MKGKEEKEGGARLGTGGGGSPDKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQPEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDDIPSALRIAKKKRWNSIEERRIHQESELHSYLTRLIAAERERELEECQRNHEGDEDDGHIRAQQACIEAKHDKYMADMNELFSQVDEKRKKRDIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLAMKEVIDAFISENGWVEDY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UNE7-1", "uniprot_id": "CHIP_HUMAN", "id": "Q9UNE7-1", "name": "E3 ubiquitin-protein ligase CHIP", "aln": "MKGKEEKEGGARLGAGGG-SPEKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDDIPSALRIAKKKRWNSIEERRIHQESELHSYLSRLIAAERERELEECQRNHEGDEDDSHVRAQQACIEAKHDKYMADMDELFSQVDEKRKKRDIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLAMKEVIDAFISENGWVEDY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q8K3-1", "uniprot_id": "F1Q8K3_DANRE", "id": "F1Q8K3-1", "name": "E3 ubiquitin-protein ligase CHIP", "aln": "MEKMAS-------------SPEKSSSAQELKEQGNRLFLSRKYQEAVTCYSKAINRNPSVAVYYTNRALCYVKLQQYDKALADCKHALELDSQSVKAHFFLGQCQLELENYEEAIGNLQRAYNLAKEQRLNFGDDIPSALRIAKKKRWNSIEEKRISQENELHAYLSKLILAEKERELDDRVK----QSDDSQNGGDISKMKSKHDKYLMDMDELFSQVDEKRKKREIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQDQLIPNLAMKEVIDAFIQENGWVEDY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XYW6-1", "uniprot_id": "Q9XYW6_DROME", "id": "Q9XYW6-1", "name": "E3 ubiquitin-protein ligase CHIP", "aln": "MTTKHIY-------------STTNLSDLQLKEQGNCLFAARKYDDAINCYSKAIIKNPTNATYFTNRALCNLKLKRWELCCQDSRRALDIDGNLLKGHFFLGQGLMEIDNFDEAIKHLQRAYDLSKEQKQNFGDDITLQLRLARKKRWNVMEEKRIQQEIELQSYLNGLIKGDMESRLANLKLN--GNVHDEQLKDKQQEIEQECDDHIKELNNIFSKVDERRKKREVPDFLCGKISFEILTDPVITPSGITYERKDIEEHLQRVGHFDPVTRVKLTQDQLIPNFSMKEVVDSFIAENEWSLDY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25638-1", "uniprot_id": "TAH1_YEAST", "id": "P25638-1", "name": "TPR repeat-containing protein associated with Hsp90", "aln": "-----------------------MSQFEKQKEQGNSLFKQGLYREAVHCYDQLITAQPQNPVGYSNKAMALIKLGEYTQAIQMCQQGLRYTS-TAEHVAIRSKLQYRLELAQGAVGSVQIPVVEVDELPEGYDRS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ***** ** * :* **.: * :* .. ::*:*:. :*: . . .::.* . : : .: .:: : *: :* . .* .:. . ", "identical_positions": 20, "similar_positions": 38, "identity": "6.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2969", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N5U6-1", "uniprot_id": "RNF10_HUMAN", "id": "Q8N5U6-1", "name": "E3 ubiquitin-protein ligase RNF10", "aln": "-MPLSSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGP-AGESKPKSDGKNSSGSKRYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDEVAEAQRAEFSPAQFSGPKKINLNHLLNFTFEPRGQTGHFE--GSGHGSWGKRNKWG--HKPFNKELFLQANCQFVVSEDQDYTAHFADPDTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDLKSVVATESHQYVVGDTITMQLMKREKGVLVALPKSKWMNVDHPIHLGDEQHSQYSKLLLASKEQVLHRVVLEEKVALEQQLAEEKHTPESCFIEAAIQELKTREEALSG--LAGSRREVTGVVAALEQLVLMAP--LAKESVFQPRKGVLEYLSAFDEETTEVCSLDTPSRPLALPLVEEEEAVSEPEPEGLPEACDDLELADDNLKEGTICTESSQQEPITKSGFTRLSSSPCYYFYQAEDGQHMFLHPVNVRCLVREYGSLERSPEKISATVVEIAGYSMSEDVRQRHRYLSHLPLTCEFSICELALQPPVVSKETLEMFSDDIEKRKRQRQKKAREERRRERRIEIEENKKQGKYPEVHIPLENLQQFPAFNSYTCSSDSALGPTSTEGHGALSISPLSRSPGSHADFLLTPLSPTASQGSPSFCVGSLEEDSPFPSFAQMLRVGKAKADVWPKTAPKKDENSLVPPAPVDSDGESDNSDRVPVPSFQNSFSQAIEAAFMKLD----TPATSDPLSEEKGGKKRKKQKQKLLFSTSVVHTK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UIW5-1", "uniprot_id": "RNF10_MOUSE", "id": "Q3UIW5-1", "name": "E3 ubiquitin-protein ligase RNF10", "aln": "-MPQSSPSAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGP-AGESKPKSDGKNSNGSKRYNRKREPSYPKNENFSNQSRRSNSQKSKTFNKMPPQRGGGSSKPFSSSSNGGRRDEVAEAQRAEFSPAQFSGPKKINLNHLLNFTFEPRGQAGHFE--GSGHGGWGKRNKWG--HKPFNKELFLQANCQFVVSEDQDYAAHFADPDTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDLKSVVATESRQYAVGDTITMQLMKREKGVLVALPKSKWVNVDHPINLGDEQLSQYSKLLLASKEQVLHRVVLEEKGALEQQLAEEKHTPESCFIEAAIQEVKIREEALSG--VAGGGGEVTGVVAALEHLVLMAP--LATESAFQPRKGVLEYLSAFDDEAAQVCSLDPPG-PLALPLVEEEEAVSEPE------ACEDAEVADDSLGEGTVGPEMSQEEPITKPGFTQLSSSPCYYFYQAEDGQHMFLHPVNVRCLVREYGSLEQSPEKISATVVEIAGYSMSEDVRQRHRYLSHLPLTCEFSICELALQPPVVSKETLEMFSDDIEKRKRQRQKKAREERRRERRIEMEENKRQGRYPEVHIPLENLQQFPAFNSYTCPSDSALGPTSTEGHGALSLSPLSRSPGSHADFLLTPLSPTASQGSPSFCVGSLEDDSPFLSFAQMLRVGKAKADGWPKTAPKKDDNSLVPPAPVDSDGESDNSDRVPVPSFQNSFSQAIEAAFMKLD----TPATSDPLSEDRGGKKRKRQKQKLLFSTSVVHTK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0UXR5-1", "uniprot_id": "B0UXR5_DANRE", "id": "B0UXR5-1", "name": "E3 ubiquitin-protein ligase RNF10", "aln": "MLESSEALTPEFGLNMEKNPNANNNSSST-----KIPPRSSSTGLNPTDSKAKTDGKNNGGSKRYSRKREPTFAKAESFPG-PRRSQPQKNKNFDKRPPQRGGAGVRQYG-LAGGGRREEVAENRRAEFSPAQFAGPKKISLNHLLNFTFEPRG--GHFGSGGDGHSCWGRRNKWGHKHKPFNKELFLQANCQFVVSDDQDYQAHFTDPDTLVDWDCVQQVRIYSHEVPSCPICLYPPVAAHMTRCGHIYCWPCMLHYLSLSEKSWSKCPICYEAVHSADLKSVVAMETRQYVSGNSITMCLMRREKGSLVALPSSQWVKVEEPIQFGDVQFCSYSKLLLASRQQVLG-LLAEERMALQTQLSQEKDDPQACFIQSALLQLQEREESLLKRRRRKTAGSVDGVDMRKLSLSEQSSPEVTVVNNLTNSKPILQYASAFDDEVQDAQ-------------EEVLEEMTNPS----------VHEAPEEIPDGDVEDLPVEETPQSSQ---TAHHGPYYYFYQAEDGQQMFLHPVNVRCLQRQYGSLENSPQTITANVVEIDGQTVTEDIRRRHRYLSHLPLTCEFSLCELDLQPPILSKETLDSFADDIEKRKRLRQKKVRDEKRREKRIEMEENRKQGKYPEVHIGLENLHHFPAFGSPPQNGPQLHLPEVLLGP----PSPLSSSPSSDG-----VMFPNLSEHSPSLSVVGVEEDSHCMSFAQMLKGGKARVDTGPKTTPKKADMFLAPPA-ADSDGESDNSDRVPVPSFQNSFSQALGQALSKLDNGNQTPAPALPISDDKGGKKKKK-KQKLLFSTSMVHTK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.. :. . :*:**..:*..*:*: : ****:*:* . :**.*:****..*****.**** ::.* *.* . .***..**.*.*:* ******.. : :. .****:**** :*********:*****.************* *** *.**. **:***** *******************:**** ***:******:** *:**** **************.**::******:**.*:*********:********.:**. ******* *::**. *::*** **:**** *****.*:*::*:.**::** * ..********::*** :: **: **: **::**. *::***::*: ::: ***:* .* ** * :. :: . : * :*:* ****:*. :. * * :::*. . * :.: :* : :: * :. .* **********:*********** *:*****.**:.*:*.**** * :::**:*:***************:*** ****::*****: *:******** ****.*:*:***:***:***::**:****** ****::****.* . . . * * **** **.*.. : *. *: ***:.* .:*:** ******: ***:.* ***:*** : *.*** .************************: *: *** ***.: *:*:::****:*: *********:****", "identical_positions": 453, "similar_positions": 185, "identity": "54.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2974", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P42346-1", "uniprot_id": "MTOR_RAT", "id": "P42346-1", "name": "Serine/threonine-protein kinase mTOR", "aln": "--------------------------MLGTGPATATAGAATSSNVS--------------------------------------VLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEESTRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNSTR---IGRFANYLRNLLPSSDPVVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGA---------DRNEGRRHAAVLVLRELAISVPTFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQRE-PKEMQKPQWYRHTFEEAEKGFDETLAK---EKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLVHDKYCKDLMGFGTKPRHITPFTSFQAVQPQQSNALVGLLGYS-SHQGLMGFGASPSPTKSTLVESRCCRDLMEEKFDQVCQWVLKCRSSKNSLIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHVLSCVK---------KEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPPKDFAHKRQKTVQVDATVFTCISMLARAMGPGIQQDI-KELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPGMPKGLAHQLASPGLT------------TLPEASDVASITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKDPDPDPNPGVINNVLATIGELAQVSG--LEMRKWVDELFVIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSQGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEVPLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLDQSP--ELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHRINHQRYDVLICRIVKGYTLADEEEDPLIYQHRMLRSSQGDALASGPVETGPMKKLHVSTINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELALTS-QDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAASGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVP---ERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQ-----------HKQELHKLMARCFLKLGEWQLNLQG-INESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKLRHASGANITNATTTATTAASAAAATSTEGSNSESEAESNESSPTPSPLQKKVTEDLSKTLLLYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPN-QPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRTTCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNAKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLN9-1", "uniprot_id": "MTOR_MOUSE", "id": "Q9JLN9-1", "name": "Serine/threonine-protein kinase mTOR", "aln": "--------------------------MLGTGPAVATASAATSSNVS--------------------------------------VLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEESTRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNSTR---IGRFANYLRNLLPSSDPVVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGA---------DRNEGRRHAAVLVLRELAISVPTFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQRE-PKEMQKPQWYRHTFEEAEKGFDETLAK---EKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLVHDKYCKDLMGFGTKPRHITPFTSFQAVQPQQPNALVGLLGYS-SPQGLMGFGTSPSPAKSTLVESRCCRDLMEEKFDQVCQWVLKCRSSKNSLIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHVLSCVK---------KEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPPKDFAHKRQKTVQVDATVFTCISMLARAMGPGIQQDI-KELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPGMPKGLAHQLASPGLT------------TLPEASDVASITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKDPDPDPNPGVINNVLATIGELAQVSG--LEMRKWVDELFIIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSQGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEVPLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLDQSP--ELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHRINHQRYDVLICRIVKGYTLADEEEDPLIYQHRMLRSSQGDALASGPVETGPMKKLHVSTINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELALTS-QDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAASGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKEDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVP---ERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTAHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQ-----------HKQELHKLMARCFLKLGEWQLNLQG-INESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKLRHASGANITNATTAATTAASAAAATSTEGSNSESEAESNENSPTPSPLQKKVTEDLSKTLLLYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPN-QPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRTTCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHKKAGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42345-1", "uniprot_id": "MTOR_HUMAN", "id": "P42345-1", "name": "Serine/threonine-protein kinase mTOR", "aln": "--------------------------MLGTGPAAATTAATTSSNVS--------------------------------------VLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEESTRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNATR---IGRFANYLRNLLPSNDPVVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGA---------DRNEGRRHAAVLVLRELAISVPTFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQRE-PKEMQKPQWYRHTFEEAEKGFDETLAK---EKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLVHDKYCKDLMGFGTKPRHITPFTSFQAVQPQQSNALVGLLGYS-SHQGLMGFGTSPSPAKSTLVESRCCRDLMEEKFDQVCQWVLKCRNSKNSLIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHVLSCVK---------KEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPPKDFAHKRQKAMQVDATVFTCISMLARAMGPGIQQDI-KELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPGMPKGLAHQLASPGLT------------TLPEASDVGSITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKDPDPDPNPGVINNVLATIGELAQVSG--LEMRKWVDELFIIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSPGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEAPLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLDQSP--ELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHRINHQRYDVLICRIVKGYTLADEEEDPLIYQHRMLRSGQGDALASGPVETGPMKKLHVSTINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELALTS-QDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVP---ERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQ-----------HKQELHKLMARCFLKLGEWQLNLQG-INESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKLRHASGANITNATTAATTAATATTTASTEGSNSESEAESTENSPTPSPLQKKVTEDLSKTLLMYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPN-QPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWCPFW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NB07-1", "uniprot_id": "A0A8M1NB07_DANRE", "id": "A0A8M1NB07-1", "name": "Serine/threonine-protein kinase TOR", "aln": "----------------------------------------MSGTAT--------------------------------------VLQQFVSGLKSRNEDTRAKAAKDLQHYVTTELRELSQDEATTFYDELNHHIFELVSSSDVNEKKGGILAIVSLIGVEGGNATR---ISRFANYLRNLLPSSDSVVMEMASKAMGHLSMAGDTFTAEYVEFEVKRALEWLGA---------DRNEGRRHAAVLVLRELAVSAPTFFFQQVQPFFDNIFYAVWDSKQAIREGAVSALRACLILTTQRE-TKEMQKPQWYKQTFEEAEKGFDETLAK---EKGMNKDDRVHGALLILNELVRISSMEGERMREEMEEITQQQLVHDKYCKELMGFSTKPRHITPFTSFQSVQPQQSNALLGLLGYS-TPQGFLSFGAAPVPSKSTLVESRYCRELMEERFDQVCRWVLKYRTSKNPLIQMTILNLLPRLAAFQPHTFTD-QYLQDTMGHLLGCLK---------KEKERTAAFQALGLLVVAVRADIQPYLSKILEIIKAALPPKDFAHKRQKTMQVDATVFTCISMLSRAMGPSIQQDV-KELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPGMPKGLAYQLSSPSLT------------NIPEASDVGSITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHLLSGHGHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDEVFEIRELAICTIGRLSSMNPAFVMPFLRKMLIQILTELEHSGVGRNKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKDPDP--NPGVVICVLATIGELAQVSG--LEMRKWMDELFPIIMDMLQDSSSLAKRQVALWTLGQQVASTGYVVEPYRKYPSLLEVLLNFLKTEQNQGIRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDSADYSTSEMLVNMGNLPLDEFYPAVAIVTLMRILRDPSLSNHHTMVVQAVTFIFKSLGLKCVQFLPQVMPTFLNVIRVCDASIREFLFQQMGMVVCFVKIHIRPYMDDIFTLIREYWTPNNPMQNTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDMSVGRNVTIKLLMAIQLFGANLDDYLHLLLPPVVKLFDAPDVPLQARKVALETLDRLTESLDFTDYASRIIHPIVRTLDVTP--ELRNSSMDTLSSLVFQLGKKYQIFIPMVNKVMLKHRINHQRYDVLICRIVKGYTLAEEEEDPLIFQHRQLRSSQSDTLVSGPVESGPMKKLHVSTTALQKAWGAARKVSKDDWLEWLRRLSVVLLKESSSPALRSCWSLAQTYIPLARDLFNAAFLSCWSELSEDQQDELIRSIELALTS-QDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEFQKGASPLILESLISINNKLQQPEAASGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKIDMNKDDPELILGRMRCLEALGEWGQLHQQCCEEWTLVSEETQAKMARMAAAAAWGLGHWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCQMLSELEEVIQYKLVP---ERRDIIRETWWERLQGCQRIVEDWQRILMVRSLVINPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSKQLDHPLPTAHPHVTYAYMKYMWKSTRKIDAFQHMQHFVQGMQQQAQHAIAAEDQQ-----------HKLELHKLMARCFLKLGEWQLSLQG-INESTIPKVLQYYSHSTEHDRNWYKAWHAWAVMNFEAVLHYKHQNQGRDEKKKLRHASGASAN-----------------SEASNSDSEADSTEHSPVPSPGQKKVNEDLSKTLLLYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPEVNEALVEGIKTIQIDTWLQVIPQLIARIDTPRALVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHCNTLVQQAIMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFAVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQDWCRKYMRSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPN-QSIIRIQSIAPSLQVITSKQRPRKLTIMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLANDPASLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMEKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHRDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYTAGQSVEAMEGIDLGETTHKKPGTTVPESIHSFIGDGLVQPEALNKKAIQIINRVRDKLTGRDFSHDETLDVPTQVELLIKQATSHENLCQCYIGWCPFW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VK45-1", "uniprot_id": "TOR_DROME", "id": "Q9VK45-1", "name": "Serine/threonine-protein kinase mTor", "aln": "-----------------------------------------MSTTS--------------------------------------VVQQFVNGLKSRNRNVQNKATQDLLFYVKTELREMSQEELAQFFDEFDHHIFTMVNATDINEKKGGALAMKCLINCEGSLTARK-GISPYLNRLRDLLLINDVSVMEIAARSLVKLANMPTSKGADSFDFDIKKAFEVLRG---------ERQEYRRHSAVFILRELAIALPTYFYQHILTFFEVIFNAIFDPKPAIRESAGEALRAALIVTAQRESTKQSSEPQWYRICYDEANGSFNADLGSSKDQKGVTRDDRIHGGLVVFNELFRCANATWERRYTSLKTLFP-KTQHNKFLEASSSSSMGSQLNTLVPRLKVPFIDKLGSTQTHLGEGEHHKGVAKFAS------HNVLESAYAQEILQEHYTSICDNVLEQRTSKSPYVQQALLQILPRLAAFNRAVFVE-KYLQTCVSHLMQILRG--------KEKDRTVAYITIGYMAVAVQSAIEVHLSSIMTSVKVALPSKDLTSKRK--VPVDPAVFACITLLAHAVKSEIADDV-KDILEQMFYTGLSPALTVCLRELSENVPQLKSAITEGLIGILSQVLMNKAAILP------YTALPTIAIDG-----------SLMQNGDGATTVLALKTLGTFNFEEQNMLDFVQRCADYFIVHEQQEIRLEAVQTCTRLLKLAVQ--SSESMENSKTLSDTVSHVIERLLMVAITDMDCNVRIRILRSLDETFDGKLAQPESLNSLFITLHDEIFEIRELAMVTIGRLSSINPAYVMPKLRTTMIELITDLKYSGMSRNKEQSAKMLDHLVISTPRLISSYMNPILKALVPKLHEPES--NPGVILNVLRTIGDLAEVNGGSDEMELWADDLLSILLEMLGDAGSPDKRGVALWTLGQLISATGRVVTPYHKYPVLIDILINFLKTEQRRSIRRETIRVLGLLGAMDPYKHKMNKGLIDSQKDNVLIAYSDGK-VDESQDISTAELLVNMGN-ALDEYYPAVAIAALMRILRDPTLSTRHTSVVQAVTFIFQSLGIKCVPYLAQVLPNLLDNVRTADNNLREFLFQQLAILVAFVKLHIISYMGDIFKLIKEFWTINTPLQNTLINLIEQIAVALGCEFRDYLAELIPQILRVLQHDNSKDRMVTRRLLQALQKFGSTLGYYLPLILPPIVKLFDSPYVPQQVSMVALETINNLACQLDFTDFSSRIIHPLVRVLDAEP--ELRDQAMTTLRSLAKQLGKKYLVFVPMVQRTLNKHRIVDPEYEELLSKIKSCSTLADSYG-AGESELRPSRFKNNEPFVTDRNSNN--KNLQVTTNELRTAWQVTRRVSKDDWVEWLKRLSIGLLKESPSHALRACRSLAQEYDTLLRDLFNAAFISCWTELSPDLKNELTQSLIQALQV-TDMPEITQTILNLAEFMEHCDRDPIPIETK----LLGTRAMACRAYAKALRYKEEEFLLREDSQVFESLILINNKLQQREAAEGLLTRYRNAANELNVQGRWYEKLHNWDEALEHYERNLKTDSSDLEARLGHMRCLEALGDWSELSNVTKHEWENFGTEAKSRAGPLAAVAAWGLQDWEAMREYVRCIPEDTQDGSYYRAVLAVHHDDFETAQRLIDETRDLLDTELTSMAGESYERAYGAMVCVQMLAELEEVIQYKLIP---ERREPLKTMWWKRLQGGQRLVEDWRRIIQVHSLVVKPHEDIHTWLKYASLCRKSGSLHLSHKTLVMLLGTDPKLNPNQPLPCNQPQVTYAYTKYMAANNQLQEAYEQLTHFVSTYSQELS---CLPPEA-----------LKQQDQRLMARCYLRMATWQNKLQDSIRPDAIQGALECFEKATSYDPNWYKAWHLWAYMNFKVVQAQKS---ALDKQQ----PPGASMG----------------MTMGSGLDSDLMIIQR---------------------YAVPAVQGFFRSISLIKGNSLQDTLRLLTLWFDYGNHAEVYEALLSGMKLIEINTWLQVIPQLIARIDTHRQLVGQLIHQLLMDIGKNHPQALVYPLTVASKSASLARRNAAFKILDSMRKHSPTLVEQAVMCSEELIRVAILWHEQWHEGLEEASRLYFGDRNVKGMFEILEPLHAMLERGPQTLKETSFSQAYGRELTEAYEWSQRYKTSAVVMDLDRAWDIYYHVFQKISRQLPQLTSLELPYVSPKLMTCKDLELAVPGSYNPG-QELIRISIIKTNLQVITSKQRPRKLCIRGSNGKDYMYLLKGHEDLRQDERVMQLFSLVNTLLLDDPDTFRRNLAIQRYAVIPLSTNSGLIGWVPHCDTLHTLIRDYRDKKKVPLNQEHRTMLNFAPDYDHLTLMQKVEVFEHALGQTQGDDLAKLLWLKSPSSELWFERRNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRMSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLIKAMEVTGIEGTYRRTCESVMLVLRRNKDSLMAVLEAFVYDPLLNWRLLDVDKKGNDAVAGAGAPGGRGGSGMQDSLSNSVEDSLPMAKSKPYDPTLQQGGLHNNVADETNSKASQVIKRVKCKLTGTDFQTEKSVNEQSQVELLIQQATNNENLCQCYIGWCPFW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35169-1", "uniprot_id": "TOR1_YEAST", "id": "P35169-1", "name": "Serine/threonine-protein kinase TOR1", "aln": "MEPHEEQIWKS-KLLKAANNDMDMDRNVPLAPNLNVNMNMKMNASRNGDEFGLTSSRFDGVVIGSN---GDVNFKP--------ILEKIFRELTSDYKEERKLASISLFDLLVSLEHELSIEEFQAVSNDINNKILELVHTKKTSTRVGAVLSIDTLISFYAYTERLPNETSRLAGYLRGLIPSNDVEVMRLAAKTLGKLAVPGGTYTSDFVEFEIKSCLEWLTASTEKNSFSSSKPDHAKHAALLIITALAENCPYLLYQYLNSILDNIWRALRDPHLVIRIDASITLAKCLSTLRNRD---PQLTSQWVQRLATSCEYGFQ-----------VNTLECIHASLLVYKEILFLKDP----------------------------------------------------------------------------------------FLNQVFDQMCLNCIAYENHKAKMIREKIYQIVPLLASFNPQLFAG-KYLHQIMDNYLEILTNAPANKIPHLKDDKPQILISIGDIAYEVGPDIAPYVKQILDYIEHDLQT-----KFKFRKKFENEIFYCIGRLAVPLGPVLGKLLNRNILDLMFKCPLSDYMQETFQILTERIPSLGPKINDELLNLVCSTLSGTPFIQPGSPMEIPSFSRERAREWRNKNILQKTGESNDDNNDIKIIIQAFRMLKNIKSR-FSLVEFVRIVALSYIEHTDPRVRKLAALTS-----CEIYVKDNICKQTSLHSLNTVSEVLSKLLAITIADPLQDIRLEVLKNLNPCFDPQLAQPDNLRLLFTALHDESFNIQSVAMELVGRLSSVNPAYVIPSIRKILLELLTKLKFSTSSREKEETASLLCTLIRSSKDVAKPYIEPLLNVLLPKFQDTSS----TVASTALRTIGELSVVGG--EDMKIYLKDLFPLIIKTFQDQSNSFKREAALKALGQLAASSGYVIDPLLDYPELLGILVNILKTENSQNIRRQTVTLIGILGAIDPYRQ----------KEREVTSTTDISTEQNAPPIDIALLMQGMSP-SNDEYYTTVVIHCLLKILKDPSLSSYHTAVIQAIMHIFQTLGLKCVSFLDQIIPTILDVMRTCSQSLLEFYFQQLCSLIIIVRQHIRPHVDSIFQAIKDFSSVAK-LQITLVSVIEAISKALEGEFKRLVPLTLTLFLVILENDKSSDKVLSRRVLRLLESFGPNLEGYSHLITPKIVQMAEFTSG--NLQRSAIITIGKLAKDVDLFEMSSRIVHSLLRVLSSTTSDELSKVIMNTLSLLLIQMGTSFAIFIPVINEVLMKKHIQHTIYDDLTNRILNNDVLPTKILEANTTDYKPAEQMEAADAGVA--------KLPINQSVLKSAWNSSQQRTKEDWQEWSKRLSIQLLKESPSHALRACSNLASMYYPLAKELFNTAFACVWTELYSQYQEDLIGSLCIALSSPLNPPEIHQTLLNLVEFMEHDDK-ALPIPTQS----LGEYAERCHAYAKALHYKEIKFIKEPENSTIESLISINNQLNQTDAAIGILKHAQQHH-SLQLKETWFEKLERWEDALHAYNEREKAGDTSVSVTLGKMRSLHALGEWEQLSQLAARKWKVSKLQTKKLIAPLAAGAAWGLGEWDMLEQYISVMKPKSPDKEFFDAILYLHKNDYDNASKHILNARDLLVTEISALINESYNRAYSVIVRTQIITEFEEIIKYKQLPPNSEKKLHYQNLWTKRLLGCQKNVDLWQRVLRVRSLVIKPKQDLQIWIKFANLCRKSGRMRLANKALNMLLEGGNDPSLPNTFKAP-PPVVYAQLKYIWATGAYKEALNHLIGFTSRLAHDLGLDPNNMIAQSVKLSSASTAPYVEEYTKLLARCFLKQGEWRIATQPNWRNTNPDAILGSYLLATHFDKNWYKAWHNWALANFEVISMVQEETKLNGGKNDDDDDTAVNNDNV--------------RIDGSILGSGSLTINGNRYPLELIQR-----------HVVPAIKGFFHSISLLETSCLQDTLRLLTLLFNFGGIKEVSQAMYEGFNLMKIENWLEVLPQLISRIHQPDPTVSNSLLSLLSDLGKAHPQALVYPLTVAIKSESVSRQKAALSIIEKIRIHSPVLVNQAELVSHELIRVAVLWHELWYEGLEDASRQFFVEHNIEKMFSTLEPLHKHLGNEPQTLSEVSFQKSFGRDLNDAYEWLNNYKKSKDINNLNQAWDIYYNVFRKITRQIPQLQTLDLQHVSPQLLATHDLELAVPGTYFPG-KPTIRIAKFEPLFSVISSKQRPRKFSIKGSDGKDYKYVLKGHEDIRQDSLVMQLFGLVNTLLKNDSECFKRHLDIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHRDAKKIPLNIEHWVMLQMAPDYENLTLLQKIEVFTYALDNTKGQDLYKILWLKSRSSETWLERRTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMRVLRDNKESLMAILEAFALDPLIHWGFDLPPQKLTEQTGIPLPLINP--SELLRKGAITVEEAANMEAEQ--------------QNETKNARAMLVLRRITDKLTGNDIKRFNELDVPEQVDKLIQQATSIERLCQHYIGWCPFW", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32600-1", "uniprot_id": "TOR2_YEAST", "id": "P32600-1", "name": "Serine/threonine-protein kinase TOR2", "aln": "MNKYINKYTTPPNLLSLRQRAEGKHRTRKKLTHKSHSHDDEMSTTSNTDSNHNGPNDSGRVITGSAGHIGKISFVDSELDTTFSTLNLIFDKLKSDVPQERASGANELSTTLTSLAREVSAEQFQRFSNSLNNKIFELIHGFTSSEKIGGILAVDTLISFYLSTEELPNQTSRLANYLRVLIPSSDIEVMRLAANTLGRLTVPGGTLTSDFVEFEVRTCIDWLTLTADNNS-SSSKLEYRRHAALLIIKALADNSPYLLYPYVNSILDNIWVPLRDAKLIIRLDAAVALGKCLTIIQDRD---PALGKQWFQRLFQGCTHGLS-----------LNTNDSVHATLLVFRELLSLKAP----------------------------------------------------------------------------------------YLRDKYDDIYKSTMKYKEYKFDVIRREVYAILPLLAAFDPAIFTK-KYLDRIMVHYLRYLKNIDMNAANNS--DKPFILVSIGDIAFEVGSSISPYMTLILDNIREGLRT-----KFKVRKQFEKDLFYCIGKLACALGPAFAKHLNKDLLNLMLNCPMSDHMQETLMILNEKIPSLESTVNSRILNLLSISLSGEKFIQSNQYDFNNQFSIEKARKSRNQSFMKKTGESNDDITDAQILIQCFKMLQLIHHQ-YSLTEFVRLITISYIEHEDSSVRKLAALTS-----CDLFIKDDICKQTSVHALHSVSEVLSKLLMIAITDPVAEIRLEILQHLGSNFDPQLAQPDNLRLLFMALNDEIFGIQLEAIKIIGRLSSVNPAYVVPSLRKTLLELLTQLKFSNMPKKKEESATLLCTLINSSDEVAKPYIDPILDVILPKCQDASS----AVASTALKVLGELSVVGG--KEMTRYLKELMPLIINTFQDQSNSFKRDAALTTLGQLAASSGYVVGPLLDYPELLGILINILKTENNPHIRRGTVRLIGILGALDPYKH----------REIEVTSNSKSSVEQNAPSIDIALLMQGVSP-SNDEYYPTVVIHNLMKILNDPSLSIHHTAAIQAIMHIFQNLGLRCVSFLDQIIPGIILVMRSCPPSQLDFYFQQLGSLISIVKQHIRPHVEKIYGVIREFFPIIK-LQITIISVIESISKALEGEFKRFVPETLTFFLDILENDQSNKRIVPIRILKSLVTFGPNLEDYSHLIMPIVVRMTEYSAG--SLKKISIITLGRLAKNINLSEMSSRIVQALVRILNNGD-RELTKATMNTLSLLLLQLGTDFVVFVPVINKALLRNRIQHSVYDQLVNKLLNNECLPTNIIFDKENE-VPERKNYEDEMQVT--------KLPVNQNILKNAWYCSQQKTKEDWQEWIRRLSIQLLKESPSACLRSCSSLVSVYYPLARELFNASFSSCWVELQTSYQEDLIQALCKALSSSENPPEIYQMLLNLVEFMEHDDK-PLPIPIHT----LGKYAQKCHAFAKALHYKEVEFLEEPKNSTIEALISINNQLHQTDSAIGILKHAQQHN-ELQLKETWYEKLQRWEDALAAYNEKEAAGEDSVEVMMGKLRSLYALGEWEELSKLASEKWGTAKPEVKKAMAPLAAGAAWGLEQWDEIAQYTSVMKSQSPDKEFYDAILCLHRNNFKKAEVHIFNARDLLVTELSALVNESYNRAYNVVVRAQIIAELEEIIKYKKLPQNSDKRLTMRETWNTRLLGCQKNIDVWQRILRVRSLVIKPKEDAQVRIKFANLCRKSGRMALAKKVLNTLLEETDDPDHPNTAKAS-PPVVYAQLKYLWATGLQDEALKQLINFTSRMAHDLGLDPNNMIAQSVPQQSKRVPRHVEDYTKLLARCFLKQGEWRVCLQPKWRLSNPDSILGSYLLATHFDNTWYKAWHNWALANFEVISMLTSVSKKKQEGSDASSVTDIN------------------EFDNGMIGVNTFDAKEVHYSSNLIHR-----------HVIPAIKGFFHSISLSESSSLQDALRLLTLWFTFGGIPEATQAMHEGFNLIQIGTWLEVLPQLISRIHQPNQIVSRSLLSLLSDLGKAHPQALVYPLMVAIKSESLSRQKAALSIIEKMRIHSPVLVDQAELVSHELIRMAVLWHEQWYEGLDDASRQFFGEHNTEKMFAALEPLYEMLKRGPETLREISFQNSFGRDLNDAYEWLMNYKKSKDVSNLNQAWDIYYNVFRKIGKQLPQLQTLELQHVSPKLLSAHDLELAVPGTRASGGKPIVKISKFEPVFSVISSKQRPRKFCIKGSDGKDYKYVLKGHEDIRQDSLVMQLFGLVNTLLQNDAECFRRHLDIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHREAKKIPLNIEHWVMLQMAPDYDNLTLLQKVEVFTYALNNTEGQDLYKVLWLKSRSSETWLERRTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAAILREKFPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMKVLRDNKGSLMAILEAFAFDPLINWGFDLPTKKIEEETGIQLPVMNA--NELLSNGAITEEEVQRVENEH--------------KNAIRNARAMLVLKRITDKLTGNDIRRFNDLDVPEQVDKLIQQATSVENLCQHYIGWCPFW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: : *.* : : .: .* : :*:* :: . :.::::*: :: . : *. *:: **. . . ** *: .* **.:*:.:: :*: : :: .:*::: .:: * .: : :*:*:::: ** * :: : .::: *: .: *.: ** .* :* .* :*: ** : . .:. :. : :*. *:: .*:. :.: : .: : . * :: : ::* **:* *. :**. : : : : ::. ::* : * . : :: :: :. * . * : .: :* ** *: .: . : . : :::*: *: :* : : *...:*.* : . :: ::. * . . . : * .:: * :. . .: :**: : :: . :* *. *. : .. * . *:.*:.:** : *:* ::* :* *. ** :***.:.*. ** :*:*: * *: *: :*****:***:*:* :*. :::::*.*:.* : **::* :* *: .: : .*::*:*..:: * ::... * .* .:*:*: *.* :* : .:*: :::. : * . ** .** :*** :::* *: * .** *: :*:*:****: ** :: ::*:***:***:: :: : :. . ::: . : :: .:. . **:*.:* : *::*:.* :** ** .:**: .**:.**::** :* *::* :: :* . :* ***: :: :*: ** .:: .* :::: . :* *:: :** * ** **: :. :. :* :: :* * : :. ::* : **..* * *: * :*:: : . :: *:..*: .::: : :***::.::* *. ** . * ** * *:*..: :*:*:::..: :::* . *: * :: . *. . : . :* :. *:.** ::: :*:** ** :***: ***:*.* .**:* *.. * .: ::***::* . * ** . :::* :: ** : .*: * :***.***** *: .:*: . ** * *:*:****:*** :* :*:** ***:*:* ::* *:* : .*::: *:***..*::** *:.. .. . . :*::*.* ***:* :* : .:* :.: . :** ***** .*: : :* : .: * :: *:* :*:: :. *. * ::**** :*:::: .***.***..:* ::::*:**:*:** :* ::: : * ** * *: :: *:::: *:***:.*::* : :*:*.** *** : *::*.* ** . . :. * *.** * : . :* ::: *.. :: : :*:***:*: . *: * . * : :* .* .****** ** **:.: . . . . : :.:**::***:**** . . ***:**:*** * :* :. :*: .*.: ::* .**:*:****:**. *.. : .** *:*: *****:*** ** ** : :*::** .*:..: *. .**:** : *.****:*:**** *:***::*** :* ::* : ** ****: : . *:** * **.:::**:* :* :* .* * : :* :***:**:**::* :*:*** :*:* :***:*: :********: .. : ::* : . :.**:*******: : **:*::: ::******:***. *****.****** :*. ::::* **:*..****.:***:****:.**:*.***::*: **: ** ** **.:****::***::*:*** :*:.:* *:** *:***** *** *::**..**********.******************::**::*********.*: ***:***:******** ****:*::*.:* **..** *** :: *:**:****. ***::* : * . . . * * :* ::.*: **** *: . :: **: **:***. *.*** ********", "identical_positions": 716, "similar_positions": 765, "identity": "26.79%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2978", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A338P6K9-1", "uniprot_id": "QSER1_MOUSE", "id": "A0A338P6K9-1", "name": "Glutamine and serine-rich protein 1", "aln": "MDAHYAPAGFAEPPAPPASAATQPAAPAW---------AYEARVPAAASSPSCSGSSPSLKASYEDGHPSQSESDVLQRQTF---------------TASHQLPGYATTPQATGMHSSAATELFVAGPLPTTGTLPPP-TLSAYQHSSTFSNRNFATTSPLVLQDSSFNTTSNGILSPHDPLLQIKTSQGTVPTALAFERLGSSALSNSVPPQSSTYRSAQESAPHLLQPQFSLLPSTLGGAQQTPQAYNSALFPSSAASIERALLRECSVIKHHQRPSVTQSIQAQLTG-SQHPLHSYLSSAS-IGNFQEPSRQSSLSCSSVRDSTQVSNGVLPQKTPQVSAELAQSYSSVIPSSGYLPSA---TKVDSCSTKQPLTSTTIPKPQSVIPPVQTLNYSKPLHNQSSVISGQAQIYSTAQLPSLLSVSQSQNYGLVQPHNVPSIVHSQVYRSSRVEKLPSLYKTLT-FSGSSQPVTSENQTLSYSSNQQEVLSLVTN-ENYPAQTRDLPSVSESQNYSSGQSQGLSPVSQTQVSYSSQSQVLSVVSPSESYASGQSLTLTAPSLSYSSASRGQSLPVSTPTPSYTSMHPSPNAQTQ-GSSAQPQEFLPAVQSS-FASSTRGQTLQSSIPSPDPKSYAERKLDSSVYTSSKQDE--FPVQKLQALQSQASLESSSQRLPDGEVN----AQESVYKTSKADDRY-SQSVTRNNSHLEDQVVGVALQGSEQEENMVGSMTQLNQQSGQSNNAVATDLKKATNLMQTPQVRLNTKDLNQQHSLMHKMHEAKVQQQHDQIMSASSQIQIPNPALGQSHQA-LPHTSVLLDSACDLQILQQAGILQASLGQAKASLQVQRVQSPQQIVHPFLQMDGHIIQSNGEHPQQQLHPHNSDIMKLDLPEPSKPLQQ-LTTKGPFSEANPHDSKNQFVSLGSICFSEAMLLSDERNILSNVDDILAATAAACGVTPSDFSKSAAN-ETMQDIESSDSKSHYQQSLNVRHVNSDFNSIAASVGKPQSINDISLNGNQVSVSLSSVPTLQSETVLDQPHMETPSQTIPTKVPSAMVGLGQEIQEQSSDPFKKQLTINHESKEDREIAVDSALSNNRNQEFVSNSRSISGDSVVSERDFTLVGDDTGVLVNPRRSTLALLAMPQPGDAASGKTEDEKQDVTYFNLPKEKAKGKEQGK---EEED-NQKQLKRSAQCKRQNPRGTDVYVPYTSPSLESCDEGFQHQEKMRQKIKEVEEKQPEVKTGFIASFLDFLKCGPKQQFSTLAVRVPNRTRRSGIQTTRTFCPPPFAKTSPAAQAP--SETGGVSLSEK-VDSELK-TLEQLSSFSSDEEDPGSCGHDIYKNTSAPLTVLDATSDKTKKTVLEALPVATPGASAETAGVAPTASTAVATIKQD-LHLTSLTVNTMENANSTESPTAIELDSLPSDQLAKGQDTVAIEGFTDEENIESGGEGQYRERDEFVVKIEDIETFKEALNTGKEPPAIWKVQKALLQKFVPEIRDGQREFAATNSYLGYFGDAKTKYKRIYVKFIENANKKEYVRVCSKKPRNKPSQTIRNIPSKPSSISKTSDPPVSKTTTTKTPS----TKPKAKQLKIKAEPPPKKRKKWKEEFSSSQSESSPEVRSSSSEDEGFEPPAPSVTRFLNTRAMKETFKSYMELLVSIALDPDTMQALEKSNDELLLPHMKKIDGMLNDNRKRLLVNLHLDQPFKNALESFPELTVITRDSKAKSGGSAISKIKMNGKAYNKKTLRTSKTTTKSAQEFAVDPEKIQLYSLYHSLHHYKYHVYLICKNEISSVQKKNEDLGQEEIVQLCMKNVKWVEDLFEKFGELLNHVQQKCS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2KHR3-1", "uniprot_id": "QSER1_HUMAN", "id": "Q2KHR3-1", "name": "Glutamine and serine-rich protein 1", "aln": "-------MNFLS--------------------------TAESRTAQAAAS------------------------------------------------GTTLLPQFRAPSWQTGMHSSAATELFATGPLPSTGTLPP--SLSAYQHPTTFSNRNFATTSPLVLQDSTFNTTSNGILSHHDPLLQIKTSQGTVPTALAFERLGSSVLSNSIPPQSSTYRSAQESAPHLLQPQFSLLPSALGGSQQTPQAYSSTLFTSSTASIERALLRECSVIKHHQRPSGTQSIQAQLTG-SQHSLHSYLSNSS-VVNFQETTRQSSLSCSPIGDSTQVSNGGLQQKTSQVSVELAQSYSSAIPSSGYPPST---TKIKSCSTEQPLTSTKTPKPQSIIPPVQTLSYSKPLHNQSSVISGQAQIYSTAQLPSLLSVSQSQNYGLVQPHNVPSIVHSQVYRSSKVEKLPPLYKTLT-FSGSSQTVTPENQTLNYSSNQQEVLSSVTN-ENYPAQTRDLSSVSQSQSYSSGHSQGLSPVSQTQVSYSSQSQVLSVVSLSESYASGESLTLTAPSLSYSSASRAQNLPDSSPTQNYISMHSSQNVQTQESSSPQSQKFLPAVQSSSFASSTHCQTLQNNITSPDPKSYAERKLDSDVYPSSKQEDG-FPMQELQVLQPQASLESSTQRLSDGEIN----AQESTYKVSKADDRY-SQSVIRSNSRLEDQVIGVALQASKKEESVVGSVTQLNQQIGQVNNAATLDLKNSTNLIQTPQIRLNTKDLKQQHPLILKVHESKVQEQHDQIINASSQIQIPNHALGHGHQASLPNTQVLLDSACDLQILQQS-ILQAGLGQVKASLQAQRVQSPQQIVHPFLQMEGHVIQSNGDHSQQQLHPQNSEVMKMDLSESSKPLQQHLTTKGHFSETNQHDSKNQFVSLGSMCFPEAVLLSDERNILSNVDDILAATAAACGVTPTDFSKSTSN-ETMQAVEDGDSKSHFQQSLDVRHVTSDFNSMTATVGKPQNINDTSLNGNQVTVNLSPVPALQSKMTLDQQHIETPGQNIPTKVTSAVVGPSHEVQEQSSGPFKKQSATNLESEEDSEAPVDSTLNNNRNQEFVSSSRSISGENATSESEFTLGGDDSGVSMNPARSALALLAMAQSGDAVSVKIEEENQDLMHFNLQKKRAKGKGQVK---EEDNSNQKQLKRPAQGKRQNPRGTDIYLPYTPPSSESCHDGYQHQEKMRQKIKEVEEKQPEVKTGFIASFLDFLKSGPKQQFSTLAVRMPNRTRRPGTQMVRTFCPPPLPKPSSTTPTPLVSETGGNSPSDK-VDNELK-NLEHLSSFSSDEDDPG-YSQDAYKSVSTPLTTLDATSDKKKKT--EALQVATTSPTANTTGTATTSSTTVGAVKQEPLHSTSYAVNILENISSSESSKPIELDGLPSDQFAKGQDTVAIEGFTDEEDTESGGEGQYRERDEFVVKIEDIETFKEALKTGKEPPAIWKVQKALLQKFVPEIRDGQREFAATNSYLGYFGDAKSKYKRIYVKFIENANKKEYVRVCSKKPRNKPSQTIRTVQAKPSSSSKTSDPLASKTTTTKAPS----VKPKVKQPKVKAEPPPKKRKKWKEEFSSSQSDSSPEIHTSSSDDEEFEPPAPFVTRFLNTRAMKETFKSYMELLVSIALDPDTMQALEKSNDELLLPHMKKIDGMLNDNRKRLLLNLHLDQSFKNALESFPELTIITRDSKAKSGGTAISKIKMNGKAYNKKTLRTSKTTTKSAQEFAVDPEKIQLYSLYHSLHHYKYHVYLICKDEISSVQKKNEDLGQEEIVQLCMKNVKWVEDLFEKFGELLNHVQQKCS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9B1-1", "uniprot_id": "E7F9B1_DANRE", "id": "E7F9B1-1", "name": "", "aln": "MERNYPSSSFTEPGSAAAQTAGWAYKPSSSYGSTQLDSELVQRQSFASSHQSTFTTTHHPTGVFDSNQHSTASSNTTESSIMNFLSAIESRSLQAGPAGSTLLPSFRSPSWQTGANS--STELFLTGALHPSGTFPTPSALSSYQHPSAFPTRSFTTASALGVQDSTFSS-SNGLLSSNDSLLQLKSSQNTVQTALAFS---GTSLGVGLPPQSSTYRSAQESAPHLLQPQFSLLSASLGSSQQAPQPYSGPAFSG---SIERALQRECSVIKHHQRPSSTQPVQEQLANSAQHSLQGYLHDESDVSYQQDLSPHTPVPCSPVGDPSPLNG-----TTQQKTASQTQAYASSVPSPGFSSSTGVKVKDGSSSIAQHPSEDTDSQVQTSSPGLQPQSYSSPTQKQSSVIASQLQPYTSTQLTGLVSVSASHTYITSQSLSN-SLSQTQAFTSSLPEKLPSIYKTLSSFASQSEAETSVSQSHIYSSSQQQDLHPSGNREGYETHVQTHCMGSPSQSYSSSHSQGLP-----TISFYTQG-PASVSIPSQNYVSSQSLTSVP---SFSSN-YSRSLSSSNPGQDYVLMQSSPGSKTD--NALLQQKYLLSVQSSTSSAATYTKVLPKDQSSVEIK---PRQEDEQMFLPSKASSGELPLEDVQALQ-KGSLVTSPQNISTSEIGEQNSAKNDIYVVSKMEDRHNTPSVIRSNSRTEEQTL-----------------SQMENTKELTTNANAKSIP---LLMHSSTLAPLSADQLKQHTLLLKGSSSQQQNHHEQIIQVQTTDPRQ-LSEGQAQFIRVPSTTQVLLDPSHMIVLQQP-VLTTAQNQPKQTMYMQSV--PVQYVH--MNSDTVNLTINGRHNQQFVS--------HQVPNSTGSTKEDPTLK---DQSSPHDIKQNFS-LNSVCFSDSMLLADERNILSNVDDILAATAAACGVTPQDFVKSTSSDGDMSSVANPVDSKCNFQSPENRHN--------------------SFPSQHMIINPQAMTVIGAQTTYSKE--ETEGHQVFTLSHSNNQ---PEERCKSAQDISDKVAN---AHEKSDVLSKGRFVNSSNGSLNTNGLAISN---TTSNDFNLANQQQSQSPHHITENVSS-NLSQQKELKGFKTNDSIIENSTDGLAKKRSRSKGSSKQTAEDENGQPKFQKKSIQVKRQNSRANET---STTSASEVSHDNFQQQEKMRQKLKEVEEKQPEVKTGFLGSFLDFLKSGSRQNLSSPPIRSPNRTRKS-SASKRPPNPLLIPFKPPPPVTPLISPEPQSVISTKRLDEELQRNLETLPSFSSDEEDSVGKNQDLQKSITSALSSLDEPSDKKQKLG-------------DNVKQLQTSSTQPVVVDQQ---------KSVEKISAED-----LLKDVPTDKLAVQLNAVAIEGLIDEELSDSGGEGMYRERDEFVVKNEDIERLTVTLKAGVEPPAIWKVQKALLQKFVPELRDGKRVFFATNSYLGYFGDAKLMYRRVHVKFLDTVNKREYVRVCSRKPQCKPMHSMRSSQAKALLAQRFAAATASDCATQKTAQQKALSKPKPKQPKAKAEPPPKKRKKWKEEFTSSPSDSSPEAVS---EDDEFTPPVPFASRFLNTRTMKETFKSFVELLVSVALDADVLNALERENDELLLPHMKRVDGMITDNRRRLLPKLRMGQIFKNALDCFPELSVVT--ELKTDCETPVFKVRLSGRAYNKKTMKPSKSPSKLPLEYTVDQQKTKWFSLYHSLQHYKYHTYLMCVEEIELLKSRGRDLGQEETVQTCMGNRSWVEGLFDRFGELLTQVQQACL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* . * . *:: .: ** : :.. ** :* :**** :*.* .:**:*. :**:***.::*..*.*:*:*.* :***:*.: ***:** :*.***:*:**.** *****. .: *. .:*************************.::**.:**:**.*... *.. ****** ************* **.:* **:. :**.*:.** . * : *: : ::.:.**.: *.: :.. .* * :.. :*:*:* :**.*: .*: .* *.* * :. . .: *: * :*. .**.* ::*****:.* * *:::**..*:*** *:.* *. . *: ::*.: ** ****.:****: *:..*:. *. .*: ***.**: * * *.* ::.: * **.***.:****. :*: :*. ** *:.*.*.:*** .. *:** .:.*. *.* .* *:.* . :*: .: *::* :**** :::* :.* .. .* : * *: *..:: .** .. :*::.:*.** :.** :*.*.:. .*:. *::. * .** :**: : ** *.**: *:*.: :*::: .** : .: *:::. : : * :**.*: * .:: *::*:**:...: : *:.: :* * :* ....: :***. :* :. .* * :: * * * * ** :: : : ** * ** : ::.:.: . :: * * .::. ** *::* *.*:**.:::**:************************ ** **::. *. : . ... ** : ** *: .::: :. ..:..: :: . .: ** .: : * * * : :*: :..: : :.*. : .. : *. * .: :.. :**. .:. :*.* .:: . : . :: :.* : . * ::. : .* *::::.* . * *::: : * *:. * ****.*..: *..: * ..:.:*:*******:**************:.*******.*.:*::*: .:* *****:. *. * :. .... :* * * * :*.**: .** *.******:*. .:* *. ::.*: ** .***.:* :.. *:** .:.*: : :*: .: : *..:*:*::* ::*****: *** :***** ********** **** :. :*::* *******************:***:* * ************* *:*::***::..**:*******:**: ** :::*. :*. .: : . .*. :* *:.. *** ** * ****************:** *:**** : :*: * **.* .:******:*******::*****:***.*.::***:.**********::***:.***:*** :*::.* *****:.****:::* . .. :.: *:::.*:******::.**:.:* . *::** :* : :******:*****.**:* :**. ::.:..****** ** ** * .***.**::*****.:*** * ", "identical_positions": 666, "similar_positions": 562, "identity": "36.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-298", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABZ3NNA2-1", "uniprot_id": "A0ABZ3NNA2_RAT", "id": "A0ABZ3NNA2-1", "name": "dual-specificity kinase", "aln": "------------------------------------------------------------------------------------------------------MAAEMNCGNISHTLVTCRELWLRPEGLHGAMFEMPHPRRYHSSERGSRGSYHEHYR-----------------------------------SRKHKRRRSRSWSSTSDRTRRRR----------------------------------------REDSYHVRSRS-YDDHS---SDRRLYDRRYCGSYRRNDYSRDRG-------------------EAYYDTDFRHS---------YEYHR-------------------------------------------------ENSSYRSQRSSRRKPRRRRRRSRTFSHSSSQ--HSSRRAK------------------------SVEDDAEGHLIYHVGDWLQ--ERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYN-------------LEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILG-PVPSRMIR-----KTRKQ------------KYFYRG--RLDWDENTSAG---------RYVRENCKPLRRYLTSEAEDHH-------------------------------------------------QLFDLIENMLEYEPAKRLTLGEALQHPFFAC------------LRTEPPNTKLWDSSRDISR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35491-1", "uniprot_id": "CLK2_MOUSE", "id": "O35491-1", "name": "Dual specificity protein kinase CLK2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MPHPRRYHSSERGSRGSYHEHYQ-----------------------------------SRKHKRRRSRSWSSSSDRTRRRR----------------------------------------REDSYHVRSRSSYDDHS---SDRRLYDRRYCGSYRRNDYSRDRG-------------------EAYYDTDFRQS---------YEYHR-------------------------------------------------ENSSYRSQRSSRRKHRRRRRRSRTFSRSSS---HSSRRAK------------------------SVEDDAEGHLIYHVGDWLQ--ERYEIVSTLGEGTFGRVVQCVDHRRGGTQVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYN-------------LEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILG-PVPSRMIR-----KTRKQ------------KYFYRG--RLDWDENTSAG---------RYVRENCKPLRRYLTSEAEDHH-------------------------------------------------QLFDLIENMLEYEPAKRLTLGEALQHPFFAC------------LRTEPPNTKLWDSSRDISR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49760-1", "uniprot_id": "CLK2_HUMAN", "id": "P49760-1", "name": "Dual specificity protein kinase CLK2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MPHPRRYHSSERGSRGSYREHYR-----------------------------------SRKHKRRRSRSWSSSSDRTRRRR----------------------------------------REDSYHVRSRSSYDDRS---SDRRVYDRRYCGSYRRNDYSRDRG-------------------DAYYDTDYRHS---------YEYQR-------------------------------------------------ENSSYRSQRSSRRKHRRRRRRSRTFSRSSSQ--HSSRRAK------------------------SVEDDAEGHLIYHVGDWLQ--ERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYN-------------LEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILG-PIPSRMIR-----KTRKQ------------KYFYRG--RLDWDENTSAG---------RYVRENCKPLRRYLTSEAEEHH-------------------------------------------------QLFDLIESMLEYEPAKRLTLGEALQHPFFAR------------LRAEPPN-KLWDSSRDISR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HYF2-1", "uniprot_id": "A0AC58HYF2_DANRE", "id": "A0AC58HYF2-1", "name": "dual-specificity kinase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MPHSRRYPSSERASRSSYQDRYRERDRDRD---------------------------RGRKPRHRRSPTYSSSSERERRARG--------------------------------------HRQDTGYARSRS-YDNRS---SDRRPYDRHYGESYRRLDHSRERDRDQNRD---------HRTPSNYYSRDASPS---------YDFRRGR--------------------------------------------DRDREDSYR-RKGSRRKHKRRRRRTRSYSASSSQRSDSGTRAL------------------------CVRDDEEGHLICRSGDVLQ--ERYEIVSTLGEGTFGRVMQCIDHRRGGAHVALKIIKNVEKYKEAARLEINVLERINEKDPENNNLCVQMFDWFDYHGHMCISFELLALSTFDFLKENNYLPYSINQVRHMAYQVCLAVKFLHENKLTHTDLKPENILFVNSDYTVTYN-------------VEKKRDERTVKNTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGSILFEYYLGFTLFQTHDNREHLAMMERILG-PVPSRMIR-----KTRKQ------------KYFYRG--RLDWDENSSAG---------RYVRENCKPLRRYLLSEAEEHH-------------------------------------------------QLFDLIEAMLEYEPSKRLTLAAALRHPFFQSG----------ISSSELSAGKSWEANRDISR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P49762-1", "uniprot_id": "DOA_DROME", "id": "P49762-1", "name": "Serine/threonine-protein kinase Doa", "aln": "MVAANLEVPTSSSSSAATKRQKDVDNKLEKCLNDMLKLKTSSNNNSTSNSNNNAIMSHSLTGEHKDPKTALEGPTSSSSSSSSKYIGESQIPVPVQLYDPQKPLLQQQQQQQRICYPIGKSNSTSQLPMGGYQRLLQHQQQQHHQQQQQQHQEQQQYPQHKRPFLNWNSFACSAMNGASDPFMQQQHMPAHQQQQHLPHKLQQSYSSSHVPKQAPKSGLAMFLQKNTNKENKFGQPMQQQPPGMMPQMYGYQAPQQQSKIGYPRTGAPLTHSASFSSAQRPTALQFHQQHQQQQHLQQQQQHPQQQQHQHSSFGVGMMSRNYYNMPKQPERKPLQTFDPYAYPKPNQMQPVKYQQQQQHPHTQFQNASAGGGGGGAAGLQYDPNTNTQLFYASPASSSSNKQPQQPQQQQQQQQSQLQQSNSVIFNHSGQQHQPHQQQQNEMSKSALGLHFIETAKPVIQDDADGHLIYHTGDILH--HRYKIMATLGEGTFGRVVKVKDMER-DYCMALKIIKNVEKYREAAKLEINALEKIAQKDPHCDHLCVKMIDWFDYHGHMCIVFEMLGLSVFDFLRENNYEPYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLKPENILFVDSDYTSHYN-------------HKINREVRRVKNTDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCILFELYLGITLFQTHDNREHLAMMERILG-QIPYRMARNHTLYSKTKT------------KYFYHG--KLDWDEKSSAG---------RYVRDHCKPLFLCQLSDSEDHC-------------------------------------------------ELFSLIKKMLEYEPSSRITLGEALHHPFFDRLPPHHRVGEVSNKQPLSSGSSSRERSHSLSR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32350-1", "uniprot_id": "KNS1_YEAST", "id": "P32350-1", "name": "Dual specificity protein kinase KNS1", "aln": "-----------------MSQNIQIGTRKRSRANMNNSTTTGPANNTSSNKTFLDNFEETRTNKLLDEMFARQNSFLTDNLRNSLDLNQADN--------------PLRPRQHQHQLFLDNENAIELDEEPRIINTTINNSNNHNSSRVDEDADDDIIFIKEQPIQFS-------------------------SPLILPSSSSINNNNNIVTSNNPGCG-----------------------------------TAATSNSTYITTPKKFKKQRTISLPQLPLSKLSYQSNYFNVPDQTNAIVPRVTQTENELLHLTGSCAKTLEGNKAVN-------LTIAHSTSP---------------------------------------------FSNPPAQIASLPQSNLKKQIGSSLRKFTSNGSSESASSNKSN-------------------------FKTDKDGHYVYQENDIFGSGGRFVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAKTELRILQTILNNDPQGQFQCLLLRECFDYKNHICLVTDLYGRSIYDFMCSNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICDETHIAQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSAIFHYEYHPPVISTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVIGESLYPIHENLEHMAMMQRINGTPFPTDIIDKMFYKSKHKLGNSPSDLNSTVIKHFDRKTLSLQWPEKNKRGDTITTEKSMKRVLQSCDRLDIYISKVLKQDYGDSLSINWNLPPEKNWSLINSKLAWKRQTHSSSSSTTDELDKETFLFWYWFIDLLRKMFEFDPTKRITAKDALDHEWFNLG-------------ILDDGIATYNNTQG---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ..: .. : . . ... . .. : : . : . : . . . . : . :: : .. *. : .. * :** : : .* : *: : **:****:*:: * . :*:*:*: *::*:***: *:. *: * ::**. . *: : : ***:.*:*: :: . * :**: .*. :. ::: :* *: :* ***: : **********: :. : : . : :*.. ::::***** *.:*:*..::*********::* **** ***:***..::.* :* :*: *:* **:***:** * .* : .. * *:* : *:* *:.. * : * : *. * . ::. ::.*:. *:*::*:.*:* ** * :* : .:. ", "identical_positions": 116, "similar_positions": 156, "identity": "12.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2987", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q69ZS7-1", "uniprot_id": "HBS1L_MOUSE", "id": "Q69ZS7-1", "name": "HBS1-like protein", "aln": "MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTAAQFIYSRRDNP-------EEEYGYEDLRE--SSNSLLNHQLSEIDQARLYSCLDHMREVLGDAVPDDILTEAILKHKFDVQKALSVVLEQDG-VQPWKEKSE---RAVCAGQPSKGKSVISRSSQSESEIVPKVAKMTVSGKKQTMGFEVPGLTSEENGLSVRAPHKGPPGDDVSVASPNIPETGTPKSALPPPSLQTSEELGSTPTPVRKSGKLRQQIDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNVNKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVAFIPTSGLSGENLTARSQSSDLTTWYKGMCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGSGFCVTGKIEAGYIQTGDRLLAMPPNETCTAKGITLHDEPVDWAAAGDHVNLTLVGMDIIKINVGCIFCGPKEPIKACTRFRARILVFNIEVPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKLLTKGQNALVELQTQRPVALELYKDFKELGRFMLRYGGSTVAAGVVTEIKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y450-1", "uniprot_id": "HBS1L_HUMAN", "id": "Q9Y450-1", "name": "HBS1-like protein", "aln": "MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTAAQFIYSRRDKPSV---EPVEEYDYEDLKE--SSNSVSNHQLSGFDQARLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVLEQDR-VQSLKDKNE---ATVSTGKIAKGKPVDSQTSRSESEIVPKVAKMTVSGKKQTMGFEVPGVSSEENGHSFHTPQKGPPIEDA-IASSDVLETAS-KSANPPHTIQASEEQSSTPAPVKKSGKLRQQIDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVGFIPTSGLSGENLITRSQSSELTKWYKGLCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAMPPNETCTVKGITLHDEPVDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVPIKACTRFRARILIFNIEIPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQTQRPIALELYKDFKELGRFMLRYGGSTIAAGVVTEIKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q5Z6-1", "uniprot_id": "F1Q5Z6_DANRE", "id": "F1Q5Z6-1", "name": "HBS1-like protein", "aln": "MSRHRNVRGYNYDEDFEDDDMYGQSVEDDYCISPATAAQFIYSRQDSRQARHVETVEEAEYEEEEEEMPTSPTMTSTLDSLQQGRLYSCLDQMRTVLGDSIPDSTLTQAALKYDCDPHRALDFILSENTNTQAPSARTNPQLEPNTTAAPQKAKVREAPESRVESEVVPKVARMTVSGKKQTMGFDVR--SAEENGGVAPSLRRGPSPEATAVPTTETPSKQS-----------TVTEDSAAPTPTRPSGKSKQQLNIRAELEKRQGGKPLLNLVVIGHVDAGKSTLMGHLLYLLGNVNKRTMHKYEQEAKKAGKASFAYAWVLDETGEERDRGVTMDVGMTKFETDSKVVTLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFEAGGQTREHALLVRSLGVTQLAVAVNKMDQVNWQQERFQEIISKLGHFLKQAGFKDSDVFYVPTSGLSGENLTTKSKVADLTAWYTGPCLVEQIDAFKPPQRSVEKPFRLCVSDVFKDQGSGFCVTGKIEAGYIQTGDKVLAMPPNETCTVKGISLHDEALDWAAAGDHVSLTVTGMDIIKINVGCVFCDPKEPIRACTRFRARILLFNIELPITQGFPVLLHYQTVSEPATIRKLVSVLHKSSGEVLKKKPKCLSKGQNAVVEIQTQRPVAMELYKDYKELGRFMLRYVGSTIAAGVVTEIKE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:******************:*************:*********:*. ** **: .* .:.. . *. ::*.*******:** ****::**. * :* ** . * ::**. :*.:: .*. . :.: . :. *.* : *: ***:*****:************:* ::**** : ::**. : . :.:.: .. : : * .::*:*.: *** :**::::********** ********************:******:***********:*********************:************** :**:*****************************************:*******.******************************* .************:*** ::********** ::*: ::** **.* **:****:*******::*******************:*************::**********.***:****.:*********.**:.***********:**.** **:**********:****:***:***************.*::*:***:**:*** ***** *:*****:**:*****:*:*****:********** ***:**********", "identical_positions": 484, "similar_positions": 123, "identity": "69.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2991", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08876-1", "uniprot_id": "KLF10_RAT", "id": "O08876-1", "name": "Krueppel-like factor 10", "aln": "MLNFGASLQQASEGKMELISEKSKEGAHPWDK-AEQSDFEAVEALMSMSCDWKSHFKKYLENRPVTPVSDTSEEDSLLPGTPDLQTVPAFCLTPPYSPSDFEPSQGSNLTAPAPPTGHFRSLSDAAKPPSIAPFKEEEKSPLAAPPLPKAQATSVIRHTADAQLCNHQSCPVKAASILNYQDNSFRRRTHINVEATRKNIPCAAVSPNRPKPEPSTAANGAEKAGTAPYDFAVPSSETVICRSSQPAPTSPVQKSVLMSSPTVSTGGVPPLPVICQMVPLPANNSLVTTVVPSSPPSQPPAVCSPVLFMGTQVPKGTVMFVVPQPVVQSPKPPVVSPNGTRLSPIAPAPGFSPSAARVTPQIDSSRVRSHICSHPGCGKTYFKSSHLKAHVRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPATASAQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89091-1", "uniprot_id": "KLF10_MOUSE", "id": "O89091-1", "name": "Krueppel-like factor 10", "aln": "MLNFGASLQQASEGKMELISEKPREGMHPWDK-AEQSDFEAVEALMSMSCDWKSHFKKYLENRPVTPVSDTSEDDSLLPGTPDLQTVPAFCLTPPYSPSDFEPSQGSNLTASAPSTGHFKSFSDAAKPPGATPFKEEEKNPLAAPPLPKAQATSVIRHTADAQLCNHQSCPVKAASILNYQDNSFRRRTHGNVEATRKNIPCAAVSPNRSKPEPSTVSDGDEKAGAALYDFAVPSSETVICRS-QPAPSSPVQKSVLVSSPTVSTGGVPPLPVICQMVPLPANNSLVSTVVPSTPPSQPPAVCSPVLFMGTQVPEGTVVFVVPQPVVQSPRPPVVSPSGTRLSPIAPAPGFSPSAARVTPQIDSSRVRSHICSHPGCGKTYFKSSHLKAHVRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPASAQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13118-1", "uniprot_id": "KLF10_HUMAN", "id": "Q13118-1", "name": "Krueppel-like factor 10", "aln": "MLNFGASLQQTAEERMEMISERPKESMYSWNKTAEKSDFEAVEALMSMSCSWKSDFKKYVENRPVTPVSDLSEEENLLPGTPDFHTIPAFCLTPPYSPSDFEPSQVSNLMAPAPSTVHFKSLSDTAKPHIAAPFKEEEKSPVSAPKLPKAQATSVIRHTADAQLCNHQTCPMKAASILNYQNNSFRRRTHLNVEAARKNIPCAAVSPNRSKCERNTVADVDEKASAALYDFSVPSSETVICRS-QPAPVSPQQKSVLVSPPAVSAGGVPPMPVICQMVPLPANNPVVTTVVPSTPPSQPPAVCPPVVFMGTQVPKGAVMFVVPQPVVQSSKPPVVSPNGTRLSPIAPAPGFSPSAAKVTPQIDSSRIRSHICSHPGCGKTYFKSSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A3Y0-1", "uniprot_id": "A0AB13A3Y0_DANRE", "id": "A0AB13A3Y0-1", "name": "", "aln": "-------------------------------------------------------------------MSSPSHS-------------EEWCMTPPSSP-DQEPLQRS-----------------QVKP----------------------QAISVIRHTSDVP-----------------------------------DLPSAP---------------------------AVAPAHTLILAS--------------------------------------------------------ASVCPP-----------SVLFVDSVLLIVSPKHTASYG----LRFIAPAPGQTSSPHTTASAGVPSRPRDHICTHPDCGKTYFKSSHLKAHLRTHTGEKPFRCCWDGCVRRFCRSDELSRHRRTHTGEKRFCCPVCHARFVRSDHLSKHTRRHLTFRRNTAASQREMNISLQPLAPKTDIC-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. *.. :*:*** ** * ** * * .** ** ******:*. ::*.*. :*..:.*:* * .:**.* :*:** . :: *.: .. * ****** :.*. .:. .** *.***:**.************** ********* *.*.** ***.****************:*.**:*. **:*****:**:****: :: . . . ::. .*.* . ", "identical_positions": 118, "similar_positions": 63, "identity": "24.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2993", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFK8-1", "uniprot_id": "D3ZFK8_RAT", "id": "D3ZFK8-1", "name": "FERM, ARHGEF and pleckstrin domain-containing protein 2", "aln": "MGEIEGTYRTLPT-SGTRLGGQTAIGVSTLEPEQALSPKM------QEKHMHIRVKLLDSTVEIFDIEPKCDGQVLLTQVWKHLNLIECDYFGLEFKNVQSYWIWLEPMKPIIRQVRKPKNAVLRLAVKFFPPDPGQLQEEYTRYLFALQLRRDLLEERLTCTATTSALLISHLLQSEIGDYDETLDREHLKANDYLPNQEQSLDKILDFHQRHTGQTPADSDFQVLEIARKLEMYGIRFHMASDREGTKINLAVSHMGVLVFQGTTKINTFNWSKVRKLSFKRKRFLIKLHPEVHGPYQDTLEFLLGSRDECKNFWKICVEHHTFFRLSDQPKPKAKAVFFSRGSSFRYSGRTQKQLVDYIRDGGTKRIPYERRHSKTRTSLHTLTGDLPKQSISFTDGLRTSASLSSANASFYPPP-TSLSSPGLPSVKDSSSSPVDPQAPHIKSTAAERSSRPSSSEGPSTQSAHLPGPPVLQPGPGFSVDSPQPSPSSLKSRLSLSPERQAS-LSTAEQGSSPVLSPVLSGTGTARMDNQEEQKHKHTSEDEAYFIAKEIVATERTYLKDLEVITVWFRSVVIKEEAMPAALMTLLFSNIDPIYEFHRGFLHEVEQRLALWEGPSS----GDHQRIGDILLRNMRQLKEFTSYFQRHDEVLTELEKATKHCKRLEAVYKEFELQKVCYLPLNTFLLKPVQRLVHYRLLLNRLCTHYSPEHEDYTDCHEALKAITEVTTELQQSLTRLENLQKLTELQRDLVGVENLIAPGREFIREGCLHKLTKKGLQQRMFFLFSDMLLYTSKSVTGASQFRIRGFLPLRGML-------VEDSENEWSVPHCFTIYAAQKTIVVAASTRLEKEKWMQDLNAAIQAAKSAGDTPAVLLGGPVYTRSPRSSDEVSLE-DSED-GRGTRGSLEGNSQHRANTTMHVCWYRNTSVSRADHSAAVENQLSGYLLRKFKNSNGWQKLWVVFTNFCLFFYKTHQDDYPLASLPLLGYSVSLPREADSIHKDYVFKLQFKSHVYFFRAESKYTFERWMEVIKRASSSPGRPPSFTQDCSHLSPGLEAEVREKEACPSLCLDKNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VS8-1", "uniprot_id": "FARP2_MOUSE", "id": "Q91VS8-1", "name": "FERM, ARHGEF and pleckstrin domain-containing protein 2", "aln": "MGEIEGTYRALPT-SGTRLGGQTAIGVSTLEPEQSLSPRM------QEKHMRIRVKLLDSTVELFDIEPKCDGQVLLTQVWKHLNLIECDYFGLEFKNVQSYWIWLEPMKPIIRQVRKPKNAVLRLAVKFFPPDPGQLQEEYTRYLFALQLKRDLLEERLTCTANTAALLISHLLQSEIGDYDETLDREHLKANEYLPNQEKSLEKILDFHQRHTGQTPAESDFQVLEIARKLEMYGIRFHMASDREGTKINLAVSHMGVLVFQGTTKINTFNWSKVRKLSFKRKRFLIKLHPEVHGPYQDTLEFLLGSRDECKNFWKICVEYHTFFRLSDQPKPKAKAVFFSRGSSFRYSGRTQKQLVDYVKDGGMKRIPYERRHSKTRTSLHALTVDLPKQSVSFTDGLRTSASLSSANVSFYPPPSSSLSPPGLPNLKDSSSSLVDPQAPVIKSTAAERSSGPSSSDGPSTQSAHLPGPPVLRPGPGFSMDSPQPSPSSLKSHLSLCPELQAA-LSTAEQGASPVLSPVLSGAGTARMDNQEEQKHKHMPEDEAYFIAKEILATERTYLKDLEVITVWFRSVLIKEEAMPAALMALLFSNIDPVYEFHRGFLHEVEQRLALWEGPSSAHLKGDHQRIGDILLRNMRQLKEFTSYFQRHDEVLTELEKATKHCKKLEAVYKEFELQKVCYLPLNTFLLKPVQRLVHYRLLLSRLCAHYSPGHRDYADCHEALKAITEVTTELQQSLTRLENLQKLTELQRDLVGVENLIAPGREFIREGCLHKLTKKGLQQRMFFLFSDMLLYTSKSVTGASHFRIRGFLPLRGML-------VEESENEWSVPHCFTIYAAQKTIVVAASTRLEKEKWMQDLNAAIQAAKTIGDSPPVLLGGPVYTRTPRSSDEVSLE-ESED-GRGNRGSLEGNSQHRANTTMHVCWYRNTSVSRADHSAAVENQLSGYLLRKFKNSNGWQKLWVVFTNFCLFFYKTHQDDYPLASLPLLGYSVSLPREADSIHKDYVFKLQFKSHVYFFRAESKYTFERWMDVIKRASSSPGRPPSFTQDCSHHSPGLEAEIREKEACPSPCLDKNL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94887-1", "uniprot_id": "FARP2_HUMAN", "id": "O94887-1", "name": "FERM, ARHGEF and pleckstrin domain-containing protein 2", "aln": "MGEIEGTYRVLQT-AGMRLGAQTPVGVSTLEPGQTLLPRM------QEKHLHLRVKLLDNTMEIFDIEPKCDGQVLLTQVWKRLNLVECDYFGMEFQNTQSYWIWLEPMKPIIRQIRRPKNVVLRLAVKFFPPDPGQLQEEYTRYLFALQLKRDLLEERLTCADTTAALLTSHLLQSEIGDYDETLDREHLKVNEYLPGQQHCLEKILEFHQKHVGQTPAESDFQVLEIARKLEMYGIRFHMASDREGTKIQLAVSHMGVLVFQGTTKINTFNWSKVRKLSFKRKRFLIKLHPEVHGPYQDTLEFLLGSRDECKNFWKICVEYHTFFRLLDQPKPKAKAVFFSRGSSFRYSGRTQKQLVDYFKDSGMKRIPYERRHSKTHTSVRALTADLPKQSISFPEGLRTPASPSSANAFYSLSP-STLVPSGLPEFKDSSSSLTDPQVSYVKSPAAERRSG-AVAGGPDTPSAQPLGPPALQPGPGLSTKSPQPSPSSRKSPLSLSPAFQVP-LGPAEQGSSPLLSPVLSDAGGAGMDCEE-PRHKRVPADEAYFIVKEILATERTYLKDLEVITVWFRSAVVKEDAMPATLMTLLFSNIDPIYEFHRGFLREVEQRLALWEGPSKAHTKGSHQRIGDILLRNMRQLKEFTSYFQRHDEVLTELEKATKRCKKLEAVYKEFELQKVCYLPLNTFLLKPIQRLLHYRLLLRRLCGHYSPGHHDYADCHDALKAITEVTTTLQHILIRLENLQKLTELQRDLVGIENLIAPGREFIREGCLHKLTKKGLQQRMFFLFSDMLLYTSKGVAGTSHFRIRGLLPLQGML-------VEESDNEWSVPHCFTIYAAQKTIVVAASTRLEKEKWMLDLNSAIQAAKSGGDTAPALPGRTVCTRPPRSPNEVSLEQESEDDARGVRSSLEGHGQHRANTTMHVCWYRNTSVSRADHSAAVENQLSGYLLRKFKNSHGWQKLWVVFTNFCLFFYKTHQDDYPLASLPLLGYSVSIPREADGIHKDYVFKLQFKSHVYFFRAESKYTFERWMEVIQGASSSAGRAPSIVQDGPQPSSGLEGMVRGKEE----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ATD1-1", "uniprot_id": "A0A8M3ATD1_DANRE", "id": "A0A8M3ATD1-1", "name": "FERM, ARHGEF and pleckstrin domain-containing protein 2", "aln": "MGEIEGSYRSLQTPAGSRLGGQHNTGISTLEPGQSLSSAMGAGGKGHNKGLQIRVQGLDEAQEFYELESKADGQLLLSDVFRRINLIESDYFGLEFQNLQMNWVWLDPSKLIVKQVRRPMNTLFRLSVKFFPPDPGQLQEEFTRYLFSLQIKRDLLDGRLSCTENTAALLASHLVQSEIGDYDDLADREFLKMNKLLPCQEHVQEKIMELHRRHTGQTPAESDFQVLEIARKLEMFGVRFHPAADREGTKINLAVAHMGLQVFQGHTKINTFNWSKIRKLSFKRKRFLIKLHPEVHGPHQDTLEFLMGSRDQCKIFWKNCVEHHSFFRLLDQPQPKSKAIFFSRGSSFRYSGRTQKQLVEYVRDSGLRRTPYQRRNSKIRMSTRSLASDVPKQNLSFNDSLRTHIPPSSITASF-----QSLHAPSVSMRAETPNQLLHLHQTQHQPLRAPSPMKQDPIKTNSQSTYAFPDS--------IAIDSPQLSPFNDKGPLCLSPSFQMSTLSLPGQAPSPLQSPILNEVGTARLDEDEEGRRKRYPTDKAYFIAKEILTTERTYLKDLEVITVWFRSAVIKENAMPEGLMTLLFSNIDPIYEFHRGFLKEIDQRLALWEGRSNAHVKGDYQRIGDVMLRNMCSLKEFTGYLQKHDEVLTELEKATKRVKKLETVYKEFELQKVCYLPLNTFLLKPIQRLMHYKLILERLCKHYSPQHRDYDDCKEALKEVAEIATQLQSSLIRLENFQKLTELQRDLIGIENLTAPGREFIREGCLYKLTKKGLQQRMFFLFSDMLLYTSKGVTATNQFKVHGQLPLHGMILIVLDAPVEESENEWSVPHCFTIYSAQRTIVVAASSKVEMNKWIEDLNMAIEMSKKCQEKSDVLLDPSLCDRSNRSSDEVSLEQESEDDMNSSRCSLDKQSHHRANTTMHVCWHRNTSVSMSDHSLAVENQLSGYLLRKFKNSNGWQKLWVVFTNFCLFFYKTHQDDFPLASLPLLGYTVSTPGESDSIHKEYVFKLQFKSHVYFFRAESEYTFERWMEVIKSAASATGRMSLLVPKGP-------AEVNVGN-----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:** * * :* ***.* *:***** *:* . * ::* :::**: **.: *::::*.*.***:**::*::::**:*.****:**:* * *:**:* * *::*:*:* *.::**:**************:*****:**::****: **:*: .*:*** ***:********: ***.** *. ** *:: :**:::*::*.*****:**************:*:*** *:*******:***:***: **** **********:*********************:*******:****:** *** ***:*:**** ***:**:**:*******************:*.:*.* :* **:**:** : * ::*: *:***.:** :.*** . ** .. : :* ...:. ::... . : . :. * . : .. :: .*** ** . *. *.*.* * . *. . *..**: **:*. .* * :* :* ::*: . *:****.***::******************.::**:*** **:********:********:*::******** *. *.:*****::**** .*****.*:*:*************: *:**:**********************:***:**:*:* *** **** *.** **::*** ::*::* ** * ****:**********:*:*** ************:************************.*:.:.:*:::* ***:**: **:*:************:**:*******:::* :**: *** **: :*. :.. .* . .: *. **.:***** :*** .. * **: :.:***********:****** :*** *****************:***********************:**********:** * *:*.***:******************:*******:**: *:*:.** . :. . . . :. : ", "identical_positions": 646, "similar_positions": 244, "identity": "59.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-2997", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2GUZ2-1", "uniprot_id": "SKA3_RAT", "id": "B2GUZ2-1", "name": "SKA complex subunit 3", "aln": "MNPIQSFHCKLRSLATVLDGETARLLRALD--GEDSDFEDSSARILCDLYSEVQTLKDDVNAHLDKARLESRESTHFIKAAKVLMKKNSADIIKLREFFQKYGYQARDKEDSACEHRVSNSSPGLAVCKDTQEPGVKQELSEPRVPRGSAPE-----------EPLRSPQLSDFGLQRYMVSQGPANPRQETVSLKEDRASETTP--AKDPSVQVLKTPRCALKMDDFECVTPKLEHFGISEYTMCLNEDYTMGLKNMKSIKSSPLSGVGGEAVETGPVTSDNSFAIPGPMIQQLEKNDVEYINSPLPPKFCTPGLKIPS-------------------SMDSTDLVSIDYPLSKPNSSPTDLEDKDCAPLILNSDECYQSFADPHSPTITSYENFT-TPSPPKVTAIPEDILQML-KYNSNLASPIDVKAMPLRRGFTSKGQSTRGAANKENW---------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C263-1", "uniprot_id": "SKA3_MOUSE", "id": "Q8C263-1", "name": "SKA complex subunit 3", "aln": "MNPIQSFHCKLRGLATTLDSETARLLRALD--GEDSDFEDSPGRILHDLHSEVQTLKDNVNALLDEARLENQESTRFKKATKILMEKNSADVRKLREFFQKYGYQARDKEDSGCEHRVNNSTPELAVCKDIQKAGVK-ELSDPCVPSGSVSE-----------EPLRSPQLSDFGLQRYIISQVPANPPQTAASLKEERVAETPP--AKDPSVQVLKTPRCALRMDDFECETPKLEHFGISEHTMCLNEDYTMGLKNMKNIKSSLLSGVSGEAIGTGPVTSDNSFAIPGPIIQQMEENDVEYVSSPLPPKFCTPGLKIPS-------------------TMDRTDLVSIDYPLSKPNSSSTDLEIKDCVPLILNSDECYQSFAEPPSSAITSCENFA-TPSPPKVTAIPEDILQMITKHSSNLASPLDVKVMPRRKG-------TRGAANKENW---------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IX90-1", "uniprot_id": "SKA3_HUMAN", "id": "Q8IX90-1", "name": "Spindle and kinetochore-associated protein 3", "aln": "MDPIRSFCGKLRSLASTLDCETARLQRALD--GEESDFEDYPMRILYDLHSEVQTLKDDVNILLDKARLENQEGIDFIKATKVLMEKNSMDIMKIREYFQKYGYSPRVKKNSVHEQEAINSDPELSNCENFQKTDVKDDLSDPPVASSCISE-----------KSPRSPQLSDFGLERYIVSQVLPNPPQAVNNYKEEPVIVTPP--TKQSLVKVLKTPKCALKMDDFECVTPKLEHFGISEYTMCLNEDYTMGLKNARNNKSE-------EAIDTESRLNDNVFATPSPIIQQLEKSDAEYTNSPLVPTFCTPGLKIPS-------------------TKNSIALVSTNYPLSKTNSSSNDLEVEDRTSLVLNSDTCFENLTDPSSPTISSYENLLRTPTPPEVTKIPEDILQLLSKYNSNLATPIAIKAVPPSKRFLKHGQNIRDVSNKEN----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58EL7-1", "uniprot_id": "SKA3_DANRE", "id": "Q58EL7-1", "name": "SKA complex subunit 3", "aln": "MNPSERFFSKLRKLTVYLETESSSLLHTSQNLKEDEEDEETGAQALYQLHSEVRALKRQVRDQVATHDTSSADLRSFIRRCLVLKQRTTEDIDSLKKHYEKYGYRPRISRLGSTEVNCTKEAEERAERDAEKLDAAEEDEETERGDCDKVDQSVTPEKMPPPVDQLQTPKLSDFGLSALQFQRVLGEAEVPLSAAPESAIALSSPPILMNLQPPQPKTPKCSLSMEE-DALTPRLEDFGISEYTMCWNNDFTMDLFNKKPPKNR-------SERNENVLKPHNVFSNTSSVLNKDVAN--KSLESPEPPEFCTPGFKIAKNHVPSTPLFNGKNDLNSPPRLNNNCPSTPELPAFETPFVSKLIKKEDREEESKIHSESQENSLRLPDLSTTNGTSWNDAPEMPKMLRYEEEALPEMPILQSNFGSSLAFKNTSGESLSRMKTGAGHMLEMKQTSVPVPEDGFNQDWCLSTPKVRVKFPAEPCTPEMPDMSSVTQDILKLVAQCKY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* . * *** *: *: *:: * :: : *:.: *: : * :*:***::** :*. : .. : * : :* ::.: *: .:::.::**** .* .. . * . :. : . : .: : . . : . ::*:******. ..: :. *. :.* : ***:*:* *:: :. **:**.*****:*** *:*:**.* * : *. . .* *: ...:::: . : .** * *****:**.. : : : * :. .. :: :* . . :. . : :. . :* *:: *: * : .**:.:.: .* . : *:. ", "identical_positions": 85, "similar_positions": 133, "identity": "16.83%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3003", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23899-1", "uniprot_id": "HNF1B_RAT", "id": "P23899-1", "name": "Hepatocyte nuclear factor 1-beta", "aln": "----MVSKLTSLQQELLSALLSSGVTKEVLIQALEELLPSP-NFGVKLET--LPLSPGSGADL-DTKPVFHTLTNGHAKG-RLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQSSGNMTDKSSQDQLLFLFPEFSQQNQ------GPGQSEDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHNLNPLLTHGSPHHQPSSSPPNKLSGVRYSQPGNNEVTSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHSLLSPDSKM-ISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIA-QSLNTSQAQGVPVINSVASSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSINTLTSMSSSKQCPLQAW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P27889-1", "uniprot_id": "HNF1B_MOUSE", "id": "P27889-1", "name": "Hepatocyte nuclear factor 1-beta", "aln": "----MVSKLTSLQQELLSALLSSGVTKEVLIQALEELLPSP-NFGVKLET--LPLSPGSGADL-DTKPVFHTLTNGHAKG-RLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQSSGNMTDKSSQDQLLFLFPEFSQQNQ------GPGQSEDTCSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHNLNPLLTHGSPHHQPSSSPPNKMSGVRYNQPGNNEVTSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHSLLSPDSKMQITVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIA-QSLNTSQAQGVPVINSVASSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSINTLTSMSSSKQCPLQAW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35680-1", "uniprot_id": "HNF1B_HUMAN", "id": "P35680-1", "name": "Hepatocyte nuclear factor 1-beta", "aln": "----MVSKLTSLQQELLSALLSSGVTKEVLVQALEELLPSP-NFGVKLET--LPLSPGSGAEP-DTKPVFHTLTNGHAKG-RLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQSSGNMTDKSSQDQLLFLFPEFSQQSH------GPGQSDDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHSLNPLLSHGSPHHQPSSSPPNKLSGVRYSQQGNNEITSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHNLLSPDGKM-ISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIA-QSLNTSQAQSVPVINSVAGSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSISTLTNMSSSKQCPLQAW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8UW00-1", "uniprot_id": "HN1BB_DANRE", "id": "Q8UW00-1", "name": "Hepatocyte nuclear factor 1-beta-B", "aln": "MFTDMVSKLTSLQQELLSALLDSGVTKDVLVQALEDLCPCPAEFGIKIEKPLSPSSANGGSDCGDSKPVFLTLTGAQGKGGKLSGDEGSEDGDDFDTPPILRELQSLNTEEAAEQRAEVDRMLSEDPWRVARTIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTAKRAALYTWYVQKQREIDRQFDR-VQGS-DPSDSASQDQVLFFFPEFNHGGHSSGAAGGSGAAVGDEGEPGSKRMRRNRFKWGPASQEILYQAYERQKNPSKEEREALVEECNRAECVQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDTYTP----HMNPLLSHTASLSHHHSSE----SKLRYSQQAASEVTSSTTISHP---------SVLQQVSPGGLDHCHGLLSTDAKM-ISVSGGVLPPVSTLTNIHSLSQSSHHHHHHHHQQAQSLIMSLAAQSLTSPQSQSVPVINSVSG-LTTLQPMQFPQSSS-------LTQLTTAHISQQPFA-------QSHMYSPKQEAGQFSHPSRYS-------TMDSSTITHLGSSKQCPLQAW", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****************.*****:**:****:* *.* :**:*:*. * *...*:: *:**** ***..:.** :************:******:***:***********************.*: ************************************** **********:***** ***:: **.* : :*.:****:**:****.: .: *.* : . .** .*:*************:******:**********************:******************************************:*:. :****:* :. : ** * :**.* . .*:***:**** ********..** *.***.*.** *:**** **************: . :: :: . * :*::* ***.:.*:*.*******:. *::***:**.*. : * . :*::**** :****: ***. *:**.**:. * . .*:* :.**********", "identical_positions": 360, "similar_positions": 107, "identity": "62.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3007", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M971-1", "uniprot_id": "AF1Q_RAT", "id": "Q5M971-1", "name": "Protein AF1q", "aln": "MRDPVSSQYSSFLFWRMPIPELDLSELEGLGLSDSPTYKSKESNSIGKMGGQATGAER-KSPEGDPLLEYSTFNFWRAPIASIRSIDLDLL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97783-1", "uniprot_id": "AF1Q_MOUSE", "id": "P97783-1", "name": "Protein AF1q", "aln": "MRDPVSSQYSSFLFWRMPIPELDLSELEGLGLSDTPTYESKDSSSVGKMNGQASGTEQ-KNPEGDPLLEYSTFNFWRAPIASIHSVDLDLL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13015-1", "uniprot_id": "AF1Q_HUMAN", "id": "Q13015-1", "name": "Protein AF1q", "aln": "MRDPVSSQYSSFLFWRMPIPELDLSELEGLGLSDTATYKVKDS-SVGKMIGQATAADQEKNPEGDGLLEYSTFNFWRAPIASIHSFELDLL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KQS5-1", "uniprot_id": "AF1Q_DANRE", "id": "A3KQS5-1", "name": "Protein AF1q", "aln": "MLDKTSSQFDSFLFWRQPIPSLDLSELEDLGISAP---KSKEMKSTKSFPRQDEDEDR----E---LSKFSTFNFWKEPIPSIDTLDFSLLL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * .***:.****** ***.*******.**:* . : *: * .: * :: * * ::******: **.** :.::.** ", "identical_positions": 41, "similar_positions": 22, "identity": "44.57%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3008", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A8H5-1", "uniprot_id": "D4A8H5_RAT", "id": "D4A8H5-1", "name": "", "aln": "----MDVERLQEALKDFEKRGKKEVCPVLDQFLCHVAKTGETMIQWSQFKGYFIFKLEKVMDDFR--TSAPEPRGPPN-PNVEYIPFDEMKERILKIVTGFNGIPFTIQRLCELLTDPRRNYTG--TDKFLRGVEKNVMVVSCVCPSSEKNNSNS---------------------LNRMNGVMFPGNSPNYTDRSNINGPGTPRP-LNRPKLSLSAPLTTNG--LPESTDSRDSDLQLSEEKGHSDSSASDSEVSSPSSGKNKHPDED---TVESEEREVKRLKFD--DEGDVRE----------------------------------------------------TASQAVSSEVSSVRAEETETASSPPEKDRENR-TRQHCTEEEEE-------------------EEEEEEEE---SFMTPREMVPERKNQEK----------------ESDDALTVNEETSEESHQTEG-SGASPSQTDS-ASERSD---SAG-ASRGGSDCRETQESGGPPARKTGECVSG-SAMEND------------EATEVTDEPVEQE-----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0VGB7-1", "uniprot_id": "PP4R2_MOUSE", "id": "Q0VGB7-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "aln": "----MDVERLQEALKDFEKRGKKEVCPVLDQFLCHVAKTGETMIQWSQFKGYFIFKLEKVMDDFR--TSAPEPRGPPN-PNVEYIPFDEMKERILKIVTGFNGIPFTIQRLCELLTDPRRNYTG--TDKFLRGVEKNVMVVSCVCPSSEKNNSNS---------------------LNRMNGVMFPGNSPNYTDRSNINGPGTPRP-LNRPKLSLSAPLTTNG--LPESTDSKDSELQLSEEKGHSDSSASESEVSLLSPVKNKHPDED---AVESEEHEVKRLKFD--KEGDVRE----------------------------------------------------TASQTVSGEVSSVRAEETETAAPPPDKDRESR-TRQHCTEEEEE-------------------EEEEEEEEEEESFMTPREMVPERKNQEK----------------ESDDALTVNEETSEESHQMEG-SGVSPAQTDS-TSERSD---SAG-ASRSGSDCLETQESGGPPSSKTGESVSVPSSMESE------------EATEVTDDPMEQD-----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NY27-1", "uniprot_id": "PP4R2_HUMAN", "id": "Q9NY27-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "aln": "----MDVERLQEALKDFEKRGKKEVCPVLDQFLCHVAKTGETMIQWSQFKGYFIFKLEKVMDDFR--TSAPEPRGPPN-PNVEYIPFDEMKERILKIVTGFNGIPFTIQRLCELLTDPRRNYTG--TDKFLRGVEKNVMVVSCVYPSSEKNNSNS---------------------LNRMNGVMFPGNSPSYTERSNINGPGTPRP-LNRPKVSLSAPMTTNG--LPESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDED---AVEAEGHEVKRLRFD--KEGEVRE----------------------------------------------------TASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEE-------------------EDEEEEEE---SFMTSREMIPERKNQEK----------------ESDDALTVNEETSEENNQMEE-SDVSQAEKDLLHSEGSE---NEGPVSSSSSDCRETEELVGSNSSKTGEILSE-SSMENDD-----------EATEVTDEPMEQD-----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L1M4-1", "uniprot_id": "P4R2B_DANRE", "id": "A1L1M4-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2-B", "aln": "----MEIDTLLEALKDFDKKVKKEASTVLDQFLCHIAKTGETLVSWSQFKTYFVFKLEKVMEDFH--ASAPEQRGPAN-PNVESIPFEEMKERILKIVNEYNGIPFTIQRLCELLTEPKRNYTG--TEKFLRGVEKNVMVVSCIYPTSEKNGCSG---------------------VNRMNGVMLSGNTSAFTER-KVNGPGTPRP-LNRQKHSMSSSLATNG--LPDSTENKDTNTPQGHSKTTSDASASGIGGPLGSSVKNKHLDDEEDEGMEEEEHEVKRLKFS--QDGNEDE----------------------------------------------------EDEDDVDEQV--VETPRSTLSKSPSDKSEDPESPSSMLQEGSEE-------------------EEEESKHEG--SAENSEDQEPSSTQPECP-------------VADSRETFTEREVPCGSDDSSEEPSDMDQSEQRAPAGVASSPELREGEEPSEVSSSSTDDNASGPTSSSSSIDSPTEGDTGSGA-----------LDLESAEEPMEQD-----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2U4-1", "uniprot_id": "PP4R2_DROME", "id": "Q9W2U4-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "aln": "MVTMENSDEIMQILERFTDLKQKEIPKELEEYLQYVAKTGDTIFKWSSLKYLFREKLLSVIKHFN--EDSPRLEEIPNYPNVDPFNYETMKSSLLERLDLFNAAPFTVQRLCELLIDPRKQYSR--IDKFMRALEKNILVVSTIDPGRKRTESENGDSLDSVVNGDLSMEVNIDIEMENNNGNADEGSSPGAGSAGCAQKASCPRSDDNDQPKAKKAKLEIDGEERSEASDETDTEVATRVKNEKDEKNDNDETDSPHEAAEIEEPDEE-VDEADQETKTTKQPAYGSQKEGEQEESFPSSADDEAEDPMVSKSIEAEKELVAQEKKREEDKKVAIEPKEEIVKKEEVVESDKPDGKVAQLGDKAVVKKSTPPADGENQEPVKVKAENEKEEKKHAPIKTEKQDDIDSTETDDAPSAEKPAEEKIASSESKPKTKSEDDPEAETKKSQPEKTETEAAEKSVSDEKQAAEPNAESENRNDLTTSKATEAAQESVEKSPVEDASSPAVEDLAAATTPQSPLGAADSAAETPPAETGDDSQASPLVAAVTPPVLALNDQPMEDTPAEEEARVSPSATVEEVVMAESANAGAMATEEAAKDDPAAMEIDDTSQEVMMQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38193-1", "uniprot_id": "PP4R2_YEAST", "id": "P38193-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "aln": "--------MSSTMLDDVDNNMMGIKSISLYELLSDVVKQGDKTRLVTAGPEQVLPDLIRHITETIPFDLFINLKNEMNDARNLVTRLNWLGKFLNDNFLQNHTFPFTILRICELCYDPFKYYKINELEKFVNALEKCCMVTSSWQVFDKTHGEKQ--------------------EDDKEKDINFIKNQEDVSLMKIPWMTENNTRELAPFIREIDSIMSVNLG--YDDEDEEEGFFDGDEDREMGNKSKRNVLLKDENFMVEEYYEDDCGINDDNSDNKGQNCQSDVTKNNSDDE-----------------------------------------------------DDDD---------NDDDYREDGADEDDEDDDHMGSTDDDEDDD-------------------EDRQAGESTKVQNFDKKNETPRKRKPTDLDN----------FEYDESPSFTNMDLTTPKKYKHTATGRFSIIESPSSSLLNAMDGSNEISSSQEEEKEDAHENHEGRSEGLLPGDELVSPSMSSSQED---------KMVAIAGITYRENISSPLGKKSR-------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. . . * : * :.* *:. : . .* : . . . * .. : : . : . . : ***: *:*** :* : *. :**:..:** :*.* : . :. :. . . .: : : : :. : .. .: . . : ::: : . . :. . .:.. * .: . ...: : .:: :: .. . : * . :.: . . . . . : . .. . . . .: ", "identical_positions": 24, "similar_positions": 107, "identity": "3.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3016", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AEC2-1", "uniprot_id": "CAMP2_RAT", "id": "D4AEC2-1", "name": "Calmodulin-regulated spectrin-associated protein 2", "aln": "MGDAADPREVRRTFIVPAIKPFDHYDFSRAKIACNLAWLVAKAFGTETVPEELREPFYTDQYDQEHIKPPVVNLLLSAELYCRAGSLILKSDAAKPLLGHDAVIQALAHKGLYVTD--QEKLVTERDLHKKPIQMSAHLAMIDTLMMAYTVEMVSIEKVIACAQQYSAFFQATDLPYDIEDAVMYWINKVNEHLKDIMEQEQKSKEHHTAEAPGGQKSPSKWFWKLVPARYRKEQTLLKQLPCIPLVENLLKDGTDGCALAALIHFYCPAVVRLEDICLKETMSLADSLYNLQLIQEFCQEYLN-HCCHFSLEDMLYAASSIKSNYLVFMAELFWWFEVVKPSFVQPRVVRPQGAEP-------------------------------------AKDMPSVPVLNAAKRNVLDSSS---SS-----------DFTSRYTRPQTHSSVSGGIRRSSSMSYVDGFIGTWPKEKRTSVHGVSFDISFDKEDNAQ--------------SSTPNRGIIRSVSNEG--LNNSRASKHIRKNLSFKPVNGGEE-------------ESIEEELHVDPHGDLKSYMPLSTNELNSNENTHHKLPNGALQNRVLLDEFGNQIETPSIEEALQIIHDTEKPPHTARPDQIANGFFLHGQDLSLLNSNIKLSQSSPDNITDP-KGALSPITDTTEVDTGIHVPSEDIPETMDEDSS------------LRDYTVSLDSDMDDASKFLQDYDIRASNPREALSPCPSTISTKSQPGSSAS--SSSGVKMTSFAEQKFRKLNHTDGKSSG-----SSSQKTTPEGSELNIPHMVSWAQIPEESGVAQ-GRDTTQLLASEMVHLRMRLEEKRRAIEAQKKKMEAAFTKQR-----QKMGRTAFLTVVKKKGDGISPLREEAAGAEDEKVYTDRAKEKESQKMDGQRSKSLADIKESMENPQGKWLKSPSTPVDPEKQWNLTSPSEETLNEGELLEYTKSIEKLNSSLHFLQQEMQRLSLQQEMLMQMREQQSWVISPPQPSPQKQIRDFKP-RQAGLSSAAAPFSADSPRPTHPSPQSSTRKSASFSVKNQRTPRPNELKITPLNRTLTPPRSVDSLPRLRRFSPSQVPIQTRSFVCFGDDGEPQ-KEPKPKEE---------------------------------IKKEPSECKGTLESCDHNPGEKEVKP--------------LESTVSEVLSQPITETVCVTPNEDQLNQPTDPPPKPV--------FPPTAPKNVNLIEVSLSDLKPPEKADVSVEKFDGESDKEQFDDDQKVCCGFFFKDDQKAENDMAVKRAALLEKRLRREKETQLRKQQLEAEMEHRKEETRRKTEEERQKKEDERARREFIRQEYMRRK-----------------QLKLMEDMDTVIKPRPQVAKQKKQRPKSIHR-----DHIESPKTPIKGPP--------VSSLSLASLNTGDTESVH-------SGKRTP-RSESVEGFLSPSRCGSRNGEKDWENASTTSSVASG-------------TEYTGPKLYKEPSAKSNKHIIQNALAHCCLAGKVNEGQKKKILEEMEKSDANNFLILFRDSGCQFRSLYTYCPETEEINKLTGIGPKSITKKMIEGLYKYNSDRKQFSHIPAKTLSASVDAITIHSHLWQTKRPVTPKKLLPTKA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C1B1-1", "uniprot_id": "CAMP2_MOUSE", "id": "Q8C1B1-1", "name": "Calmodulin-regulated spectrin-associated protein 2", "aln": "MGDAADPREMRRTFIVPAIKPFDHYDFSRAKIACNLAWLVAKAFGTENVPEELGDPFYTDQYDQEHIKPPVVNLLLSAELYCRAGSLILKSDAAKPLLGHDAVIQALAQKGLYVTD--QEKLVTERDLHKKPIQMSAHLAMIDTLMMAYTVEMISIEKVIACAQQYSAFFQATDLPYDIEDAVMYWMNKVNEHLKDIMEQEQKSKEHHPAEAPGGQK-----------ARYRKEQTLLKQLPCIPLVENLLKDGTDGCALAALIHFYCPAVVRLEDICLKETMSLADSLYNLQLIQEFCQEYLN-HCCHFSLEDMLYAASSIKSNYLVFMAELFWWFEVVKPSFVQPRVVRPQGAEP-------------------------------------AKDVPSVPVLNAAKRNIRDSSS---SS-----------DFSSRYTRPQTHSSASGGIRRSSSMSYVDGFIGTWPKEKRTSVHGVSFDISFDKEDSAQ--------------SSTPNRGIIRSVSNEGLTLNNSRASKHIRKNLSFKPVNGEEE-------------ESIEEELHVDPHGDLQSPMPLNTNELNSNESTHYKLPNGALQNRVLLDEFGNQIETPSIEEALQIIHDTERPPHTPRPDQIANGFFLHGQDLSILNSNIKLNQSSPDNLTDT-KGALSPITDTTEVDTGIHVPSEDIPETMDEDSS------------LRDYTVSLDSDMDDASKLLQDYDLRASNPREALSPCPSTISTKSQPGSSAS--SSSGVKMTSFAEQKFRKLNHTDGKSSG-----SSSQKTTPEGSELNIPHVVSWAQIPEEAGVAP-GRDTTQLLASEMVHLRMRLEEKRRAIEAQKKKMEAAFTKQR-----QKMGRTAFLTVVKKKGEGISPLREEAAGAEDEKVYTDRAKERESQKMDGQRSKSLADIKESMETPPGRWLKSPTTPVDPERQWNLTSPSEETLNEGEILEYTKSIEKLNSSLHFLQQEMQRLSLQQEMLMQMREQQAWVISPPQPSPQKQIRDFKP-RQAGLSSAAAPFSSDSPRPTHPSPQSSTRKSASFSVKNQRTPRPNELKITPLNRTLTPPRSVDSLPRLRRFSPSQVPIQTRSFVCFGDDGEPQ-KEPKQKEE---------------------------------IKKEPSECKGTLGPCDHNPGEKEIKP--------------VESTVSEVLSQPITETVCVTPNEDQLSQPTEPPPKPV--------FPPTAPKNVNLIEVSLSDLKPPEKADVSVEKLDGESDKEQFDDDQKVCCGFFFKDDQKAENDMAMKRAALLEKRLRREKETQLRKQQLEAEMEHKKEETRRKTEEERQKKEDERARREFIRQEYMRRK-----------------QLKLMEDMDTVIKPRPQAAKQKKQRPKSIHR-----DHIESPKTPIKGPP--------VSSLSLASLNTGDSESVH-------SGKRTP-RSESVEGFLSPSRCGSRNGEKDWENASTTSSVASG-------------TEYTGPKLYKEPSAKSNKHIIQNALAHCCLAGKVNEGQKKKILEEMEKSDANNFLILFRDSGCQFRSLYTYCPETEEINKLTGIGPKSITKKMIEGLYKYNSDRKQFSHIPAKTLSASVDAITIHSHLWQTKRPVTPKKLLPTKA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08AD1-1", "uniprot_id": "CAMP2_HUMAN", "id": "Q08AD1-1", "name": "Calmodulin-regulated spectrin-associated protein 2", "aln": "MGDAADPREMRKTFIVPAIKPFDHYDFSRAKIACNLAWLVAKAFGTENVPEELQEPFYTDQYDQEHIKPPVVNLLLSAELYCRAGSLILKSDAAKPLLGHDAVIQALAQKGLYVTD--QEKLVTERDLHKKPIQMSAHLAMIDTLMMAYTVEMVSIEKVIACAQQYSAFFQATDLPYDIEDAVMYWINKVNEHLKDIMEQEQKLKEHHTVEAPGGQKSPSKWFWKLVPARYRKEQTLLKQLPCIPLVENLLKDGTDGCALAALIHFYCPDVVRLEDICLKETMSLADSLYNLQLIQEFCQEYLN-QCCHFTLEDMLYAASSIKSNYLVFMAELFWWFEVVKPSFVQPRVVRPQGAEP-------------------------------------VKDMPSIPVLNAAKRNVLDSSSDFPSSGEGATFTQSHHHLPSRYSRPQAHSSASGGIRRSSSMSYVDGFIGTWPKEKRSSVHGVSFDISFDKEDSVQ--------------RSTPNRGITRSISNEGLTLNNSHVSKHIRKNLSFKPINGEEEA------------ESIEEELNIDSHSDLKSCVPLNTNELNSNENIHYKLPNGALQNRILLDEFGNQIETPSIEEALQIIHDTEKSPHTPQPDQIANGFFLHSQEMSILNSNIKLNQSSPDNVTDT-KGALSPITDNTEVDTGIHVPSEDIPETMDEDSS------------LRDYTVSLDSDMDDASKFLQDYDIRTGNTREALSPCPSTVSTKSQPGSSAS--SSSGVKMTSFAEQKFRKLNHTDGKSSG-----SSSQKTTPEGSELNIPHVVAWAQIPEETGLPQ-GRDTTQLLASEMVHLRMKLEEKRRAIEAQKKKMEAAFTKQR-----QKMGRTAFLTVVKKKGDGISPLREEAAGAEDEKVYTDRAKEKESQKTDGQRSKSLADIKESMENPQAKWLKSPTTPIDPEKQWNLASPSEETLNEGEILEYTKSIEKLNSSLHFLQQEMQRLSLQQEMLMQMREQQSWVISPPQPSPQKQIRDFKPSKQAGLSSAIAPFSSDSPRPTHPSPQSSNRKSASFSVKSQRTPRPNELKITPLNRTLTPPRSVDSLPRLRRFSPSQVPIQTRSFVCFGDDGEPQLKESKPKEE---------------------------------VKKEELESKGTLEQRGHNPEEKEIKP--------------FESTVSEVLSLPVTETVCLTPNEDQLNQPTEPPPKPV--------FPPTAPKNVNLIEVSLSDLKPPEKADVPVEKYDGESDKEQFDDDQKVCCGFFFKDDQKAENDMAMKRAALLEKRLRREKETQLRKQQLEAEMEHKKEETRRKTEEERQKKEDERARREFIRQEYMRRK-----------------QLKLMEDMDTVIKPRPQVVKQKKQRPKSIHR-----DHIESPKTPIKGPP--------VSSLSLASLNTGDNESVH-------SGKRTP-RSESVEGFLSPSRCGSRNGEKDWENASTTSSVASG-------------TEYTGPKLYKEPSAKSNKHIIQNALAHCCLAGKVNEGQKKKILEEMEKSDANNFLILFRDSGCQFRSLYTYCPETEEINKLTGIGPKSITKKMIEGLYKYNSDRKQFSHIPAKTLSASVDAITIHSHLWQTKRPVTPKKLLPTKA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B5I3-1", "uniprot_id": "A0A8M3B5I3_DANRE", "id": "A0A8M3B5I3-1", "name": "", "aln": "MGDLSESRDPRKTFIVPAIKPFDHYDFNRAKIRASLTWLVAKAFGTDSVPEELNEPFYKDQYEQEHLKPPVADLLLSAELYCRAGSLILKSDAVKPLLGHDAVIQALAQKGLYVTD--QERLVTERDLQKKPIQMSAHLAMIDTLMMAYTVETVSVEKVMACMHQYSTDYPDGDVPYDTEDAVTSWMNKVNEYLKEIIMQEQRRMEAQNAEPVENPKSPTKWYMKLVPARYRKEQVLPKCLPWIPPVDNLLKDSTDGCALAALLHFYCPTTVSLRDICLNETMSLADSLYNLQLIQDFCREQLN-HCCHFSLEDMLYAHSSIKNNYLVFMAELFWWFEVVKPPFVQPQVLDTEAPAPS------------------------------------LKDLPPMPISKVTKRSFMERPP---SP-----------DRPSLPLRPQPQTSGSSEIKRSTSMSFVESFMGTWPKEKKSPAQGVSFEIPFD-EDSNN--------------KTTTGRGMTRSVSTEGFGFKMPHGTRGIKRNLSFQPVNGKNM--------------GIEEEGCPDTLSENHN------SRLNGSG-------------------------PPSIEEALEIIHNSEKKSQSPRAHLPSEGFFLHLQSKSEFNP--KAKDSQLDSVSESSKGVAS--TSTTEVDTGIHVRTEDIQETLDEDSS------------LRDCTVSMEFDMD------QDFEARASRSQGSTSPCPSSLSAKSPAGSIPTPAFTPGIKLTSFAEQKLRKLNPN-TETKG-----APFQGTTPDGSDLAIPHSVSWAPSPEISPAHQPSKDPAQAMAAEMVQLRMRLEEKRRAIEAQKKKVEAAFTRHR-----QKMGRSAFLTVVKRKGVDGASLSQEDTPTSEE-------------------SKTPVGTPQPVKSP-------------------LKSAGEDGTSEADLMEYTRSIEKLNASLSFLQTEMQRLAQQQEVIMQMREQQAWVVSPHQPSPQKQVRELRG---SGARSSGSPSPADSPRATHRSPTNLKRKSASFHSKTPRTPRPSELKIAPFNRVLTVPQSVDSIPRLRRFSPSQP--MSCSFSYMGNEKKPLSTADKDIEQGLEALSIECSSDTITSPTKETQQAVTDDTDLHAKKAEDVEEESRKDIKQTEKREKLKKPKTDIKP-------AVESTVSEVLSQIVMETVIVTP--------TEP-------------FDIAHQTNKNLIEVPLSVLKPLEG-KALEEEVEKEASGENQDDDQKACCGFFFKDDMKEEDSMAMKRAALLEKRLRRERESQQRKQQLEAEHEQKKEEARLKAEEERLKKEEEKARREFIKQEYLRRK-----------------QLKLMEDMDTLVKPRPTGAKQRKPRPKSIHR-----DVMESPRTPVRATAGSRPRVFSVSSLSLASL--GDNDSVN-------SDKKTPSRPDSADGCLSPTR--SRNGEKDWENGSTTSSLTSN-------------TEYTGPKLYKEPSAKSNKHIIQNALAHCCLAGKVNEGQKNKILEEMEKSGANNFLILFRDSGCQFRSLYMYCPEAEEINKLAGIGPKTISRKMIDGLYKYNSDRKQFSQIPAKTMSASVDAITIHSHLWQTKKPGTPKKVAAVKS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZAU8-1", "uniprot_id": "PTRO_DROME", "id": "A1ZAU8-1", "name": "Patronin", "aln": "-------------------MDVETQEIRQARQRASVKWLLSKAFNNR-VPDNLKEPFYRDHENQERLKPQIIVELGNATLYCQT-LANLYSDPNYQSMNHWSIIQTLARKGVPVAESADMPITETVLIQTNPLRINAHMSVIESLMVLYAKEISSGDRVMAAIRRISGNNYQAPTGQSYEQALLGWISHACAALKKRIIKEVDAG-------------------------LPDDNGSRLQTPDIPPVR-DFQDLCDGICLALLISYYCPKVVPWTSVRINYLPAVEDSIHNILLVCNFSQKHLPYTVMHMTPEDVTYMRGSMKLNLVVLLTDLFNLFEIHPAKCVCYPGMDGQVPHSNSFGGGLNRRSTPPNEYQTVQSNNFDGNHAEAFVVHKSRGITTLASMHSQQQQQLHQQQQ--HQQQYHQQPLQQHPSQSQLQIQQQEPLVPARLRQAKEKTNVESKADERGRRSRRNSSSEDSQLTIENFGGSQDQLNTLGRYERDRERKLSNTSVGSYPVEPAVAVRSSIADARGTLQLGYDTDSGSEKQDRETEKYSMRRQVSVDNVPTVSSHNLSNAGSPLPVARHKQHSSDKDYSSNSGMTPDAYNDSRSTSGYDPESTPVRKSSTSSMPASPAAWQLDVGDDDMRSLENASKLSTIRMKLEEKRRRIEQDKRKIEMALLRHQEKEDLESCPDVMKWETMSNESKRTPDMDPVDLDKYQQSIAIMNMNLQDIQQDIHRLATQQSQMQAQHLQAQQLMQAQQIANMLNQAYNAPVSAYSSRPPSRDPYQQQLHHQQQQPMPMPQPMQYVNEHGQYMSPPQPAHYMPQQAQQPQSIYSDNGAAYNHSNHSPYGGTPQYRSSVVYDDYGQPTNHFYLHESSPQPQAHQHPQRRTWAHSAAAAAYEQQQQIQPSLVDVNAWQTQQHQKQKQTWMNRPPSSAGAPSPGSFMLHQNGGGGGGGGGGGELQHLFQVQASPQHGQRQVSGSNGVQRQQSLTNLRDNRSPKAPQNMGMPMGMPMQQEDMMAPQSICFIGDEEDVDELERNIIESMQSTHISDFVHQQQQQHQHQQQLQQQQRLQGHSGRGSSSEDYDSGEMISNKLNITSGNLTYRIPSPSRPSIQANSFQDPRAMAAASGGEDQPPEKGFYISFDDEQPKRPKPPLRAKRSP---------KKESPPGSRDSVDNQATLKRESLSHLHNNNNIGFGNDDVNSKPVTRHSIHGLNNSNSVKSPGNATYNKYTDEPPIQLRQLAVSGAMSPTSNERHHLDDVSNQSPQQTQQPMSPTRLQQSSNNAEAAKNKALVIGADSTNLDPESVDEMERRKEKIMLLSLQRRQQQEEAKARKEIEASQKREKEREKEEERARKKEEQMARRAAILEQHRLKKAIEEAEREGKTLDRPDLHVKLQSHSSTSTTPRLRQQRTTRPRPKTIHVDDASVDISEASSISSRGKKGSSSNLTGYGQLSSNSMKRDYYRGSQDSLTVKESPDDYPSTSSTPIGRRGSYKTSREPAGVERGRTLSRISVAKGSTLNFRGRKSNSLMNLCGPKLYKQPAAKSNRGIILNAVEYCVFPGVVNREAKQKVLEKIARSEAKHFLVLFRDAGCQFRALYSYQPETDQVTKLYGTGPSQVEEVMFDKFFKYNSGGKCFSQVHTKHLTVTIDAFTIHNSLWQGKRVQLPSKKDMALVI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :: :*: ..: **::***.. **::* :*** *: :**::** : * .* ***:: * **. :.* ::**:**:**: *:: : :. ::.:*:::.**:::*::**: *: * * ::*:*. :: * . *:*: *:.:. **. : :* .:: * ** * ::* ** .** *: :*** .* .: :: :: **::*: *: :*.:: * *:: **: * .*:* * :*::::** **: . * : : . . :.:..:. : ::. . * * .. .. ::::.. : *:. . :..: . . ::.:: .. : . .. .: . .. . :*.:.. .* : .::: .. . : . : *. . : .: . :. .:. : :. * :.. :.. : : : * : **:.::*. :: . :: ::: : : .. : . . :.::. .. :. :* . .: : : . . * .. .*. : *: . : . : : :: : : .: : : * :. * :. * .: . :: : : . : .. .. . * . . :. :..::: :: : : . : . : : * * ** :::* . . : .:. * :. :* : : . : . . : ... . . : . . ... * ***: : ** . : *: * . .. *. : :... . : .. :* *: : : . :* :*. . : : . : . . * .:. . . : * : :.* :: :: *:*.:: : * : * * .:::*: * * **. ***:: *** * ::: :* ::** .. .* .** : : ***:** * *:. . :. ..** *: . . : * . * ..: * .. : . . : . : *::.. : ******:*:****: ** **: :* :.* **. *:*:**:: :* *::**:****:*****:** * **::::.** * **. : . *:: ::****. * **:: :* ::.::**:***. *** *: *.* . ", "identical_positions": 229, "similar_positions": 465, "identity": "13.57%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3022", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2GV05-1", "uniprot_id": "RBM5_RAT", "id": "B2GV05-1", "name": "RNA-binding protein 5", "aln": "------------------------------MGSDKRVSRTERSGRYGSIIDRDDRDERES-----------------------------------RSRR-RDSDYKRSSDDR---RGDRYDD-----------------------------------------------------YRDYDSPERERERRNSDRSEDGYHSDGDYGEHDYRHDISDERES-------------------------------------KTIMLRGLPITITESDIREMMESFEGPQPADVRLMKRKTGVSRGFAFVEFYHLQDATSWMEANQKKLVIQGKHIAMHYSNPRPKFEDWLCNKCCLNNFRKRLKCFRCGADKFDSEQEVPPGTTESVQSVDYYCDTIILRNIAPHTVVDSIMTALSP---YASLAVNNIRLIKDKQTQQNRGFAFVQLSSAMDASQLLQILQSLHPPLKIDGKTIGVDFAKSARKDLVLPDG------NRVSAFSVASTAIAAAQWSSTQSQSGEGGNVDYSYMQPGQDGYTQYTQYSQDYQQFYQQQTGGLESDAS------ATSGTTVTTTSAAVVSQSPQLYN--QTSNPPGSPTEEAQPSTSTSTQAPAASPTGVVPGT----KYAVPDTSTYQYDESSGYYYDPTTGLYYDPNSQYYYNSLTQQYLYWDGEKETYVPAAESSSNQQA-----GLPST--KEGKEKKEKP-----------KSKTAQQIAKDMERWAKSLNKQKEN-FKNSFQPVNSLREEERR----ESAAADAGFALFEKKGALAERQQLIPELVRNGDEE-NPLKRGLVAAYSGDSDNEEELVER-------------LESEEEKLADWKKMACLLCRRQFPNRDALVRHQQLSDLHKQNMDIYRRSRLSEQELEALELREREMKYRDRAAERREKYGIPEPPEPKRKKQFDAG-TVNYEQPTKDG--------IDHSNIGNKMLQAMGWREGSGLGRKCQGITAPIEAQVRLKGAGLGAKGSAYGLSGADSYKDAVRKAMFARFTEME", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YE7-1", "uniprot_id": "RBM5_MOUSE", "id": "Q91YE7-1", "name": "RNA-binding protein 5", "aln": "------------------------------MGSDKRVSRTERSGRYGSIIDRDDRDERES-----------------------------------RSRR-RDSDYKRSSDDR---RGDRYDD-----------------------------------------------------YRDYDSPERERERRNSDRSEDGYHSDGDYGEHDYRHDISDERES-------------------------------------KTIMLRGLPITITESDIREMMESFEGPQPADVRLMKRKTGVSRGFAFVEFYHLQDATSWMEANQKKLVIQGKHIAMHYSNPRPKFEDWLCNKCCLNNFRKRLKCFRCGADKFDSEQEVPPGTTESAQSVDYYCDTIILRNIAPHTVVDSIMTALSP---YASLAVNNIRLIKDKQTQQNRGFAFVQLSSAMDASQLLQILQSLHPPLKIDGKTIGVDFAKSARKDLVLPDG------NRVSAFSVASTAIAAAQWSSTQSQSGEGGSVDYSYMQPGQDGYTQYTQYSQDYQQFYQQQAGGLESDTS------ATSGTTVTTTSAAVVSQSPQLYN--QTSNPPGSPTEEAQPSTSTSTQAPAASPTGVVPGT----KYAVPDTSTYQYDESSGYYYDPTTGLYYDPNSQYYYNSLTQQYLYWDGEKETYVPAAEASSNQQT-----GLPST--KEGKEKKEKP-----------KSKTAQQIAKDMERWAKSLNKQKEN-FKNSFQPVNSLREEERR----ESAAADAGFALFEKKGALAERQQLLPELVRNGDEE-NPLKRGLVAAYSGDSDNEEELVER-------------LESEEEKLADWKKMACLLCRRQFPNRDALVRHQQLSDLHKQNMDIYRRSRLSEQELEALELREREMKYRDRAAERREKYGIPEPPEPKRKKQFDAG-TVNYEQPTKDG--------IDHSNIGNKMLQAMGWREGSGLGRKCQGITAPIEAQVRLKGAGLGAKGSAYGLSGADSYKDAVRKAMFARFTEME", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52756-1", "uniprot_id": "RBM5_HUMAN", "id": "P52756-1", "name": "RNA-binding protein 5", "aln": "------------------------------MGSDKRVSRTERSGRYGSIIDRDDRDERES-----------------------------------RSRR-RDSDYKRSSDDR---RGDRYDD-----------------------------------------------------YRDYDSPERERERRNSDRSEDGYHSDGDYGEHDYRHDISDERES-------------------------------------KTIMLRGLPITITESDIREMMESFEGPQPADVRLMKRKTGVSRGFAFVEFYHLQDATSWMEANQKKLVIQGKHIAMHYSNPRPKFEDWLCNKCCLNNFRKRLKCFRCGADKFDSEQEVPPGTTESVQSVDYYCDTIILRNIAPHTVVDSIMTALSP---YASLAVNNIRLIKDKQTQQNRGFAFVQLSSAMDASQLLQILQSLHPPLKIDGKTIGVDFAKSARKDLVLSDG------NRVSAFSVASTAIAAAQWSSTQSQSGEGGSVDYSYLQPGQDGYAQYAQYSQDYQQFYQQQAGGLESDAS------SASGTAVTTTSAAVVSQSPQLYN--QTSNPPGSPTEEAQPSTSTSTQAPAASPTGVVPGT----KYAVPDTSTYQYDESSGYYYDPTTGLYYDPNSQYYYNSLTQQYLYWDGEKETYVPAAESSSHQQS-----GLPPA--KEGKEKKEKP-----------KSKTAQQIAKDMERWAKSLNKQKEN-FKNSFQPVNSLREEERR----ESAAADAGFALFEKKGALAERQQLIPELVRNGDEE-NPLKRGLVAAYSGDSDNEEELVER-------------LESEEEKLADWKKMACLLCRRQFPNKDALVRHQQLSDLHKQNMDIYRRSRLSEQELEALELREREMKYRDRAAERREKYGIPEPPEPKRKKQFDAG-TVNYEQPTKDG--------IDHSNIGNKMLQAMGWREGSGLGRKCQGITAPIEAQVRLKGAGLGAKGSAYGLSGADSYKDAVRKAMFARFTEME", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NE58-1", "uniprot_id": "A0A8M1NE58_DANRE", "id": "A0A8M1NE58-1", "name": "", "aln": "------------------------------MGADKRVSRTERSGRYGSEQSRDD-DRRDR-----------------------------------RDRDDRGYDSHRWSDDR---RSDRYDGDRGDRGDRGD------------------------------------RGDRGDRYWSRDSPERGRKRRNSDGSEDGHHSDGDYSEHDYRGDPADEKES-------------------------------------KTIMLRGLPMNTSEADIRAAIDLLEGPKPMDVRLMKKRTGISRGFAFVEFYHLQAATRWMETNQKLLCVQGKPVVVHYSNNRHKFEDWLCNSCGLYNFRRRLKCFRCGAAKADSESSSTTGTTETQPSGDYYGDTIILRNIAPLSTVEAILGALAP---FANLLPGNIRLIKDKQTGQNRGFAFVQLASPLEASQLLTILQGLQPPLKLDGKTIGVDYAKSARKDLLLPDG------NRVSAFSVASTAIAAAQWSSSQPQQIVEPTSEYSYLQEG------YVPCSQEYQAYYQQQAGAVDPSLANGILGAAPGVKVVPAATGVVISQSAQVYQSPQAAQIEGKAQCITATATISAPATSAVSATATATSTSQENQANVPDTSSYQYDESSGYYYDPITGLYYDPNTQYYYNSQTQQYLYWDGEKQAYLPAVDSNAQNAM-----ASTSTPQKEGKEKKEKP-----------KSKTAQQIAKDMERWAKSLNKQKEN-FKSSFQPIS---QEERR----EAAAADAGFTLFEKKPGALER--LVTEASKMAEEESCSSKVGLVAAYSGDSE-PEELID--------------GDDREDKLTDWKKLACLLCRRQFPSKEALIRHQQLSDLHRQNLEVMRRSKLSEAELEELERKETEMKYRDRAAERREKYGIPEPPVPKKRKYTAPTPVVNYEQPTKDG--------LNSDNIGNKMLQAMGWKEGKGLGRNQQGITTPIEAQLRAKGAGLGTKGSSYNLTASDTYKDAVRKAMFARFTEIE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPY4-1", "uniprot_id": "Q9VPY4_DROME", "id": "Q9VPY4-1", "name": "RNA-binding protein 5-A", "aln": "MDSSSRRSFSGGSENEGGRGSDYYRSRPGSRYSRSRSRSRERNRSHGGIRHRNSRSRSRDRDRSPVFRNDQHRGGRGGAGNGDPDLYHSLINDDYRDQDERNYNSRSNFENRQFRRHDSFDRRHRDRDGESDRELNDYEYEQRSRDLDSRDRSSTDRDWYHNRSRSREHSRPWNRNNNHDDRSRSNERNTRHRDHRMYNGGGSNHNRDRDRDRDREQDRERDRDRDRDRERRGSSDYDSDEGHMRRNKYRSTTEALNIIIIFGLTKEMTRADIMSELIKVNMEPACIRIIRKQGTDSSRGIAFVEFNTVEEAKQWMDITQGVLKLNDERVSMRYSHKR--IQDWNCNKCGVCNFKFRFYCFVCKTSREDSETTFSSGSEGVDEVSTILTKKIMLRNLDALTNEEAVLTALQLHLKDLSKTVSKVLISRDSLTQASRGICYLHFDTLVDSMNVHNALTALDPPLTLDDRVVAITYCIDLEEQQALPKNPKELAVKDSTVNSGNISAVSPSGLGGNYTLADVPRLAEYSASLYASN-PAEHAYYVQYYTEYYTADINKNNRDSH-----LTEANSGAAVALSAIQRKQKKMSSIETTITAAATAAAQAAAQVKATLAAQVASAPKGNDGK----IYPTPDVTQYQYDETSGYYYDSTTGLYYNAHSQYYYNNETGAYLYWDQRRSTYVLATPASTQAALQEVLADAEQKGEEESKKAKEKE-----GGNKHDKVKVAKKIVKDMEKWAKQLNQKKDYTAVATPQPILAN-EVATTSRGNQGGYADVGFSILEKKE--------RGKLNDYAPNPTVGPMNKLVNAYGGTSDSEEDNAASSQNTQSSAVVSGGGGAEESDYVDFHKLTCLLCKRAFQSLEILQKHLKMSTLHKENLAKLNQN--TSSSIEEA------LAYRDRAKERRLKYGESDPPPPNRSRERFEQEIKTLQSRQKQSTSATPAMPISSSNVGSRLLQKMGWSEGQGLGRKNQGRTQIIEADGRSNYVGLGNKSG--QMIPGNDYKSYIKKMMKQRYENA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A023GRW3-1", "uniprot_id": "A0A023GRW3_DROME", "id": "A0A023GRW3-1", "name": "RNA-binding protein 5-A", "aln": "MDSRYGHSFSGGNGNGSESG---YR-----RYSRSRSRSRERSRDRNEYRRRNSRSRSRE--RSSHYRNDRSP---------DRDLYRDLINEDYEDQG--NYNSRQNLDQR--HGEDKYDRRHADSQGRRD---HDSNYDKSGQDMD-KDR---DHRWKNYDRVSRER--------NHDDFDRGSERSSRSNDQRQFNNNGNSNSSSSYRDREKERDRDRRCSSDED------SDMASEFRQRGAYNSGSSVEPLNNIILFGLKKHVTEADIMGELIKVDLEPTSIRVMRKQQTGASRCFAFVEFKTVEEATRWMELTQGVLQLGDHRVTMQYSHTR--ISDWTCIKCGASNFKRRFQCYMCNASRAESENALYGAGEGVDEISQILTKKIMLRGLDALTNEEGVLTALQQRLPELAKTVSKVLVSRDALTNASRGICYLNFDTLIDSMNVFNGLTALDPPLTLDDKTVIVTYCIDSENRQMMP--------AEGNFFRAGETAMSPSAITAAYTLADVPRLAEYSASVYASN-PLEHANYVQYYTDYYTTEISKNCRDRQ-----VTEANSGAAVALSAIQRKQRKVSQMETTVS---------VTEAKVAFLARGESAPKGNDGK----KYDTPDVSKYQYDETSGYYYDHVTGLYYDAHSQYYYNNETGAYLYWDQKRSTYVLATPASTQAALKEVLADAEKK-EEEAKKAKEKEKEKEEAGGKPDKVKVAKKIVKDMEKWAKQLNQKKDYTAVATPQPILSDTEAATTSRASQGAYADVGFSILEKKE--------LGKLNDYVPEAGPPAISKLVGAYGGPSDSEDDNSAN-QKALEASVGTKRAISDESDYVDFQKLTCLLCMRAFQSLDILQKHLKMSNLHKENLDKLKRNPAVEAGTDEG------LSYRDRAKERRLKYGESDPPPPNRSRERFEQEIKTLQSRQKDSFGATAAMPISSTNVGSRLMQKMGWSEGQGLGKKNQGRTEIIEADGRSNNVGLGNNTG--HMAPGNDYKSYIKKMMKQRYENA-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* **. . *:. .. ..: . : : ::* * :* . *. .* :* . .. .:..*. . . * *:: : *:: ** :.:** : .: . : *: *. ** :***** :: *. **: .* * : .. : ::**: * :.** * .* **: *: *: * : : :** . ..*:**.: . : :.:: ** .:: : :* * .**:.:::: : ::: :: * .*.***.:*.:.: : :. . .: :. . :*::.: . . :** . :. * * :* : . . : . . ...: ..: :. :: . : . . : : *.. .. .**.: *****:****** *****:.::*****. * ***** .:.:*: *. :.:: :*.*: *** * *.*::*.****:***.**::*: : **: : :.. **.**:::*** : : ** **.* *: :: *.. .*::*::**** * * . : * :* ::* **::*: .:. . : : ***** *** *** .:** *:: : . :. *:. :. *:*.:::* *** **.***:: ** * ***: * : .*** : . : .: **. ::* * *: : ", "identical_positions": 189, "similar_positions": 255, "identity": "18.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3023", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V887-1", "uniprot_id": "S39A6_RAT", "id": "Q4V887-1", "name": "Zinc transporter ZIP6", "aln": "-------------------MATNLSVIMILTFALWVTN-------PLHELQSTAAFSQTTEKINSNWESGINVDVAVTMQRHHLQQLFYRYGENDSLSVEGFRKLLQNIGIDKIKRVHIHHDHER------------------------HSDHERHSDHERHSHRGHAAAGKNSRKAFCPDLDSDNSGKNPNTSQGKGSRPAEHVNGRRNGKESASSSEVTSAVYNTVSEGTHFLETIETPKPGRRT-KDINPSTPPSITEKSRVGRLSRLARRKGNDSVSEPRKSFMYSRTSNDNIQECFNATKLLTSHGMSVQALLNATEFNYLCPAIINQIDARSCLIHTASEKKAEIP-----------------PKTYS---------LQIAWLGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDALLHLLPHSHASHHHSHSHEEPAMEMKRGPLFSHLSAQNLEESSYFDSTWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQKKPENDEDVESKKQLSKYESQLSTNEEKVDTGERPESYLQADSQEPSPFDSQQPTLLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLG----------------QSDDLIHHHHDYHHILHHHHHQNHHPHSHSQR----YSREELKDAGIATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPEMLHNDASDHGCSRWGYFFLQNAGILLGFGIMLLISIFEHKIVFRINF----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C145-1", "uniprot_id": "S39A6_MOUSE", "id": "Q8C145-1", "name": "Zinc transporter ZIP6", "aln": "-------------------MATDLSVIMILTFALWVTS-------PLHELQSTAAFSQTTEKINSNWEPGVNVDLAVTMQRHHLQQLFYRYGENDSLSVEGFRKLLQNIGIDKIKRVHIHHDHEHHADHEHHSDHEHHSDHEHHSDHEHHSDHEHHSDHEHHSHRSHTVAGKNNRKAFCPDLDSDNSGKNPRTSLGKGSRPAEHMNGRRNIKESASSSEVTSAVYNAVSEGTRFVETIETPKPGRRT-KDVNPSTPPSITEKSRVGRLSRLARKKSNESVSEPRKSFMYSRNTNDNIQECFNTTKLLTSHGMSIQALLNATEFNYLCPAIINQIDARACLIHTASEKKAEIP-----------------PKTYS---------LQIAWLGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDALLHLLPHSHASHQHSHSHEEPAMEMKRGPLFSHLSAQNIEESSYFDSTWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQKKPENDEDVESKKQLSKYDSQLSSNEEKVDPGERPESYLRADSQEPSPFDSQQPTMLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLG----------------QSDDLIHHHHDYHHILHHHHHQNHHPHSHSQR----YSREELKDAGIATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPEMLHNDASDHGCSRWGYFFLQNAGILLGFGIMLLISIFEHKIVFRINF----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13433-1", "uniprot_id": "S39A6_HUMAN", "id": "Q13433-1", "name": "Zinc transporter ZIP6", "aln": "-------------------MARKLSVILILTFALSVTN-------PLHELK-AAAFPQTTEKISPNWESGINVDLAISTRQYHLQQLFYRYGENNSLSVEGFRKLLQNIGIDKIKRIHIHHDHDHHSDHEHHSDHER------HSDHEHHSEHEHHSDHDHHSHHNHAASGKNKRKALCPDHDSDSSGKDPRNSQGKGAHRPEHASGRRNVKDSVSASEVTSTVYNTVSEGTHFLETIETPRPGKLFPKDVSSSTPPSVTSKS---RVSRLAGRKTNESVSEPRKGFMYSRNTNENPQECFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTS-EKKAEIP-----------------PKTYS---------LQIAWVGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQKKPENDDDVEIKKQLSKYESQLSTNEEKVDTDDRTEGYLRADSQEPSHFDSQQPAVLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLG----------------QSDDLIHHHHDYHHILHHHHHQNHHPHSHSQR----YSREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPEMLHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFEHKIVFRINF----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6L8F3-1", "uniprot_id": "S39A6_DANRE", "id": "Q6L8F3-1", "name": "Zinc transporter ZIP6", "aln": "MMTFLCTRSGRRASGVECRIAAERAYFRVRGLPVANMIGWWPRLCPVMSLALLWACSVGAGSDCKSVAIETDSRIAEQTQQRHLQALFDKYGQNGSISLEGLFNLLKGVGLDRIRKVMVHHPGNAHN--------------------HTHTHDHTHTHVDKLTAHTHPVTTKKGDMDHSVEKSDPVPKAQPDPASGKKSQSDAHHNLYMKMNQ-ESTTALTTPSYVTRSRRTNRSADYDFTQDHASF-----SPSQPNVTHSN---------HTHHDEDTPTHQHDDHDEHEHARASLGCQNASTILQTHGMRKEASLSVKDFSFLCPALLMQIDSKSCIVHEDEDEHSDHSHHHKHHHHHHDHQHLQHPHNHTNGRGQRNTPVYIAWLGGFLSITLISLLALVGVVLIPLMNRVCFNFLLSFLVALAVGTLSGDALLHLIPHSQGHHHHGHSEEH------------------AEEEDSLRPVWTGLTALSGVYIMFLIEHFLTLGKMYKDKNQKVQKRVDLTTEVLESEKLPSLE----ENDVKIEAAETNGG----------------RALAEEEEVMLG----AELYNDID---CENKCHSHFHDTVG----------------QSDEQHHHHHDYHHILHHHHSQNHHPHTHTHRHTHSYSQQHFEQAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMSVRQAMLYNLLSALMGYLGMIIGILIGHYAENVATWIFALTAGLFMYVALVDMVPEMLHNDASEAGFSHYGFFLLQNAGILLGFGIMLIIAVFEDRIQLDLGY----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSL7-1", "uniprot_id": "FOI_DROME", "id": "Q9VSL7-1", "name": "Zinc transporter foi", "aln": "--------------------------------------------MARHIMAVCVVCLLCAHRLHCQDHIESLLGPARVTTHNSQDQLNARVYTNLSPSSE---------TTDRRQQRSASGDDDTFN----------------------YSISPPSRREKRHAGHEHGPTSESRVPQITQYYLEKLMAQDELMN------SSGFDGLLQQLSLHSLASGASEGTCVPGSRLVHHVQPHDHHHAHHHE------EEDHSLQLNN-----CTLIQNGTTSNVICPSLPNNNTHPLGKEAKNFTLSDKDLLHLCPILLYELKAQSGGCIEPAILSDIDTTEELLEAEKDKDIFYV-----------------------------------WIYAFISVFACGILGLVGVAIIPFMGSRYYKYIIQYLVALAVGTMTGDALLHLLPHSLAGQDERGMIMKGLGCLGGIIFFYVMEHALTMISEWRKSVEKKETKKP--SRAKVMRDPDSSVNNSVAGDKICKQKYSSYPYCYDEITMNNKQSEWMHLPFDVAAGAGGDAPSVAELRNGVGDHDGSNDMAAAAESLISPLHTNCVEMNHHNHNHKHNSHQQNHEGQDSNTIVTDLDGNAVYAVNKAKDKDSRNDHVTVILREHESSHHGHSHRHG------HVHSPPETLSAVAWMIIMGDGLHNFTDGMAIGAAFAENIAGGFSTSLAVFCHELPHELGDFAILIKAGMSVKSAVYYNLLTGVLSFIGMIFGIAFGQSQD-VAQWMFAVAAGLFIYIALVDMMPEISASHKS------LGQFLLQILGMLSGVGIMLLIALYEGDLMSAFGTAGAASHQHAH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : . * : : * : * * * * *: :: : :: .: : : * : :. . : . . : . :: : . *. .. : : .: .. ... : : . * *.. . . : **:: :**: ::. ::. *: .*::: .:*.*:** ::*:*. :::::.:********::***:***:*** . :.. . . .. . * ::.. : : .: ::: . . : . : .: . . : * ::. : : :::.*.: *: . :. . . ::*: :: :.* ..** *:* : : . ::::***:*********:**:******:*.::.*:***:***************:*:****:*:.*: ** *:.::.::** ** :*: : *: *:**::****:*:*****:**: .. * * *:** *:* *.****:*:::* : :. ", "identical_positions": 135, "similar_positions": 195, "identity": "15.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3027", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P32563-1", "uniprot_id": "VPP1_YEAST", "id": "P32563-1", "name": "V-type proton ATPase subunit a, vacuolar isoform", "aln": "--------MAEKEEAIFRSAEMALVQFYIPQEISRDSAYTLGQLGLVQFRDLNSKVRAFQRTFVNEIRRLDNVERQYRYFYSLLKKHD-------IKLYEGDTDKYLDGSGELY---VPPSGSVIDDYVRNASYLEERLIQMEDATDQIEVQKND-LEQYRFILQSG-------------------------DEFFLKGDNT-----DSTSYMDEDMIDANGENIAAAIGASVN-------------YVTGVIARDKVATLEQILWRVLRGNLFFKTVEIEQPVYDVKT---REYKHKNAFIVFSHGDLIIKRIRKIAESLDANLYDVDSSNEGRSQQLAKVNKNLSDLYTVLKTTSTTLESELYAIAKELDSWFQDVTREKAIFEILN---KSNYDTNRKILIAEGWIPRDELATLQARLGEMIARLG--------------------------------------IDVPSIIQVLDTNHTPPTFHRTNKFTAGFQSICDCYGIAQYREINAGLPTIVTFPFMFAIMFGDMGHGFLMTLAALSLVLNEKKINKMK-----RGEIFDMAFTGRYIILLMGVFSMYTGFLYNDIFSKTMTIFKSGWKWP------------------DHWKKGESITATSVG--TYPIGLDWAWHGT-ENALLFSNSYKMKLSILMGFIHMTYSYFFSLANHLYFNSMIDIIGNFIPGLLFMQGIFGYLSVCIVYKWAVDWVK------DGKPAPGLLNMLINMFLSPGT------IDDELYPHQAKVQVFLLLMALVCIPWLLLVKPLHFKFTHKK----KSHEPLPS---------TEADASSEDLEAQQLISAMDADDAEEEEVGSGSHG-EDFGDIMIHQVIHTIEFCLNCVSHTASYLRLWALSLAHAQLSSVLWTMTIQIAFGFRG---FVGVFMTVALFAMWFALTCAVLVLMEGTSAMLHSLRLHWVESMSKFFVGEGLPYEPFAFEYKDMEVAVASASSSASS", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P37296-1", "uniprot_id": "VPP2_YEAST", "id": "P37296-1", "name": "V-type proton ATPase subunit a, Golgi isoform", "aln": "---------MNQEEAIFRSADMTYVQLYIPLEVIREVTFLLGKMSVFMVMDLNKDLTAFQRGYVNQLRRFDEVERMVGFLNEVVEKHAAETWKYILHIDDEGNDIAQPDMADLINTMEPLSLENVNDMVKEITDCESRARQLDESLDSLRSKLNDLLEQRQVIFECSKFIEVNPGIAGRATNPEIEQEERDVDEFRMTPDDISETLSDAFSFDDETPQDRGALGNDLTRNQSVEDLSFLEQGYQHRYMITGSIRRTKVDILNRILWRLLRGNLIFQNFPIEEPLLEGK-----EKVEKDCFIIFTHGETLLKKVKRVIDSLNGKIVSLNTRS---SELVDTLNRQIDDLQRILDTTEQTLHTELLVIHDQLPVWSAMTKREKYVYTTLN---KFQQES--QGLIAEGWVPSTELIHLQDSLKDYIETLG--------------------------------------SEYSTVFNVILTNKLPPTYHRTNKFTQAFQSIVDAYGIATYKEINAGLATVVTFPFMFAIMFGDMGHGFILFLMALFLVLNERKFGAMH-----RDEIFDMAFTGRYVLLLMGAFSVYTGLLYNDIFSKSMTIFKSGWQWP------------------STFRKGESIEAKKTG--VYPFGLDFAWHGT-DNGLLFSNSYKMKLSILMGYAHMTYSFMFSYINYRAKNSKVDIIGNFIPGLVFMQSIFGYLSWAIVYKWSKDWIK------DDKPAPGLLNMLINMFLAPGT------IDDQLYSGQAKLQVVLLLAALVCVPWLLLYKPLTLRRLNKNGGGGRPHGYQSVGNIEHEEQIAQQRHSAEGFQGMIISDVASVADSINESVGGGEQGPFNFGDVMIHQVIHTIEFCLNCISHTASYLRLWALSLAHAQLSSVLWDMTISNAFSSKNSGSPLAVMKVVFLFAMWFVLTVCILVFMEGTSAMLHALRLHWVEAMSKFFEGEGYAYEPFSFR------AIIE-------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VE75-1", "uniprot_id": "Q9VE75_DROME", "id": "Q9VE75-1", "name": "V-type proton ATPase subunit a", "aln": "------------MGDMFRSEEMALCQMFIQPEAAYTSVSELGETGCVQFRDLNVNVNAFQRKFVTEVRRCDELERKIRYIETEIKKDG----------------IVLPDIQ-DDIPRAPNP-REIIDLEAHLEKTESEMIELAQNEVNMKSNYLELTELRKVLENTQGFFSD----------------------------QEVLNLDSSNRAGGD---NDAAAQHRGRLG-----------------FVAGVINRERVFAFERMLWRISRGNVFLKRSDLDEPLNDPAT---GHPIYKTVFVAFFQGEQLKNRIKKVCTGFHASLYPCPSSHNEREEMVRNVRTRLEDLKLVLSQTEDHRSRVLATVSKNLPSWSIMVKKMKAIYHTLN---LFNMDVTKKCLIGECWVPTNDLPVVQKALSDGSAAVG--------------------------------------STIPSFLNVIDTNEQPPTFNRTNKFTRGFQNLIDAYGVASYRECNPALYTCITFPFLFAVMFGDLGHGLILVLFGAWMVLCERKLARIRN----GGEIWNIFFGGRYIILLMGLFAMYTGLVYNDVFSKSMNLFGSRWFNN---------YNTTTVLTN--PNLQLPPNSSAVG--VYPFGMDPVWQLA-DNKIIFLNSFKMKLSIIFGVLHMVFGVCMSVVNFTHFKRYASIFLEFVPQILFLLLLFGYMVFMMFFKWFSYNARTSFQPETPGCAPSVLIMFINMMLFKNTEPP-KGCNEFMFESQPQLQKAFVLIALCCIPWMLLGKPLYIKFTRKNK--AHANHNGQLTG-------NIELAEGETPLPTGFSGNEENAGGAHGHDDE------PMSEIYIHQAIHTIEYVLSTISHTASYLRLWALSLAHAQLSEVLWQMVLSLGLKMSG---VGGAIGLFIIFGAWCLFTLAILVLMEGLSAFLHTLRLHWVEFMSKFYEGMGYAFQPFSFKAILD---GEEEE-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VE77-1", "uniprot_id": "Q9VE77_DROME", "id": "Q9VE77-1", "name": "V-type proton ATPase subunit a", "aln": "MSKWWSCGSNQESNSIFRSEVMSLVQMYLQPEAAYDTIAALGEVGCVQFRDLNAKINAQQRKFIGEVRRCDELERRIRYVTAELNKEG----------------HKVLDLM-DDFPPAPQP-REIIDLELHLEKTETEILELAANNVNLQTSYLELSEMIQVLERTDQFFSD----------------------------QESHNFD-LNKMGTH---RDPEKSN-GHLG-----------------FVAGVISREREYAFERMLWRISRGNVFVRRCDVDVALTDPKT---GNVLHKSVFVVFFQGDQLQARIRKVCTGFHAHMYPCPSSHSERQEMVKNVRTRLEDLQVIINQTSDHRTCVLQAALKQLPTWSAMVKKMKGIYHTLN---LFNVDLGSKCLIGEGWVPKRELELVEVALAAGSASVG--------------------------------------STVPSFINVLDTKKEPPTHFRTNKFTRGFQNLIDAYGIAGYREVNPGLYTCITFPFLFAVMFGDMGHGTILFLLGLWMVIDEKRLSKKR-----GGEIWNIFFAGRYIIMLMGLFAMYTGFHYNDIFSKSINVFGTRWVNV---------YNRTTVLTN--PTLQLNPSVATRG--VYPMGIDPIWQSA-SNKIIFLNTYKMKLSIIFGVLHMVFGVCMSVENFVFFKKYAYIILQFVPQVLFLLLMFGYMCFMMFYKWVKYSPTTDVEADTPGCAPSVLIMFIDMVLFKTETAL-PGCDVNMFPIQKNLEMIFLVVALLCIPWILLGKPLYIKYQRRNRPAGPVEEVDEIVE-------KIEVTTGKEIIITEVAEAHE-SGGHSEEDDE------PMSEIWIHQAIHTIEYILSTISHTASYLRLWALSLAHAQLSEVLWTMVLAMGLQMNG---YVGAIGLFFIFAVWEFFTIAIMVMMEGLSAFLHTLRLHWVEFMSKFYVGNGYPFTPFSFKDILI---VVEDD-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKF6-1", "uniprot_id": "Q9VKF6_DROME", "id": "Q9VKF6-1", "name": "V-type proton ATPase subunit a", "aln": "------------MGDMFRSEKMALCQLFIQPEAAYASIAELGEKGCVQFRDLNEEVSAFQRKYVNEVRRCDDMERRLRYVESEMKKDE----------------VKLPVLRPEEEPIAPNP-REIVDLEAQLEKTDNELREMSANGASLDANFRHMQELKYVLENTEGFFSD----------------------------QEVINLDVNRKLDPEDPANLPGAAQRGQLA-----------------FVAGVIKLERFFSFERMLWRISRGNIFLRRADIDGLVADEET---GRPVLKTVFVAFFQGEQLKQRIKKVCTGYHAAVYPCPSSHAERKEMIKDVNVRLEDLKLVLSQSADHRSRVLNSASKHLPRWSIMVRKMKAIYHILN---FFNPDVTGKCLIGEGWVPTNDISTVQDALARASKISE--------------------------------------SSIPAFMNVIETNEMPPTYTRTNKFTNGFQNLVDSYGMASYREVNPALYACITFPFLFAVMFGDLGHGLILLLFASWLIIKEKQLSSIK------EEIFNIFFGGRYIIFLMGIFSIYTGFIYNDVFSKSMNIFGSAWHMN---------YTRDVVEDENLKYITLRPNDTVYK--TYPFGMDPIWQLA-DNKIIFLNTFKMKLSIIVGVIHMIFGVSMSVVNFAYYKKYASIFLEFLPQVLFLLLLFGYMVFMMFFKWVVYN-DTVEGPLSPACAPSILILFINMILQGSQDTP-EPCKEFMFDGQKSIQQVFVVVAIICIPWMLLGKPLYIMIKRKTN--------------------------------GAPPPKPQSGGGEGHGEDD------EMGEIFIHQAIHTIEYVLSTVSHTASYLRLWALSLAHAQLSEVLWNMVFSMGFKYDS---YIGGILIYVFFGAWALLTVGILVLIEGLSAFLHTLRLHWVEFMSKFYEGAGYAFEPFAFKTILD---VSEDD-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9Z1G4-1", "uniprot_id": "VPP1_MOUSE", "id": "Q9Z1G4-1", "name": "V-type proton ATPase 116 kDa subunit a 1", "aln": "------------MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEEMDRKLRFVEKEIRKAN----------------IPIMDTG--ENPEVPFP-RDMIDLEANFEKIENELKEINTNQEALKRNFLELTELKFILRKTQQFFDEAELHHQ--------------------QMADPDLLEESSSLLEPNEMGRGAP---LRLG-----------------FVAGVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVT---GDYVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKMKAIYHTLN---LCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSG--------------------------------------STVPSILNRMQTNQTPPTYNKTNKFTHGFQNIVDAYGIGTYREINPAPYTVITFPFLFAVMFGDFGHGILMTLFAVWMVLRESRILSQKH----ENEMFSMVFSGRYIILLMGLFSIYTGLIYNDCFSKSLNIFGSSWSVRPMFTQG--NWTEETLLGSSVLQLNPAIPGVFGG--PYPFGIDPIWNIA-TNKLTFLNSFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMSSLFGYLVILIFYKWTAYDAH------SSRNAPSLLIHFINMFLFSYP----ESGNAMLYSGQKGIQCFLIVVAMLCVPWMLLFKPLILRHQYLRKKHLGTLNFGG-----------IRVGNGPTEEDAEIIQHDQLSTHSEDAEE------FDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLHVRS---LAGGLGLFFIFAAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYTGTGFKFLPFSFEHIRE---GKFDE-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25286-1", "uniprot_id": "VPP1_RAT", "id": "P25286-1", "name": "V-type proton ATPase 116 kDa subunit a 1", "aln": "------------MGELFRSEEMTLAQLFLQSEAAYCCVSELEELGKVQFRDLNPDVNVFQRKFVNEVRRCEEMDRKLRFVEKEIRKAN----------------IPIMDTG--ENPEVPFP-RDMIDLEANFEKIENELKEINTNQEALKRNFLELTELKFILRKTQQFFDE---------------------------MADPDLLEESSSLLEPNEMGRGAP---LRLG-----------------FVAGVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVT---GDYVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKMKAIYHTLN---LCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSG--------------------------------------STVPSILNRMQTNQTPPTYNKTNKFTHGFQNIVDAYGIGTYREINPAPYTVITFPFLFAVMFGDFGHGILMTLFAVWMVLRESRILSQKN----ENEMFSMVFSGRYIILLMGLFSIYTGLIYNDCFSKSLNIFGSSWSVRPMFTIG--NWTEETLLGSSVLQLNPAIPGVFGG--PYPFGIDPIWNIA-TNKLTFLNSFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMSSLFGYLVILIFYKWTAYDAH------SSRNAPSLLIHFINMFLFSYP----ESGNAMLYSGQKGIQCFLIVVAMLCVPWMLLFKPLILRHQYLRKKHLGTLNFGG-----------IRVGNGPTEEDAEIIQHDQLSTHSEDAEEPTEDEVFDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLHVRS---LAGGLGLFFIFAAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYTGTGFKFLPFSFEHIRE---GKFDE-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q93050-2", "uniprot_id": "VPP1_HUMAN", "id": "Q93050-2", "name": "V-type proton ATPase 116 kDa subunit a 1", "aln": "------------MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEEMDRKLRFVEKEIRKAN----------------IPIMDTG--ENPEVPFP-RDMIDLEANFEKIENELKEINTNQEALKRNFLELTELKFILRKTQQFFDE---------------------------MADPDLLEESSSLLEPSEMGRGTP---LRLG-----------------FVAGVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVT---GDYVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKMKAIYHTLN---LCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSG--------------------------------------STVPSILNRMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHGILMTLFAVWMVLRESRILSQKN----ENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLNIFGSSWSVRPMFTY---NWTEETLRGNPVLQLNPALPGVFGG--PYPFGIDPIWNIA-TNKLTFLNSFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYKWTAYDAH------TSENAPSLLIHFINMFLFSYP----ESGYSMLYSGQKGIQCFLVVVALLCVPWMLLFKPLVLRRQYLRRKHLGTLNFGG-----------IRVGNGPTEEDAEIIQHDQLSTHSEDADEPSEDEVFDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKS---LAGGLVLFFFFTAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIRE---GKFEE-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BB25-1", "uniprot_id": "A0A8M2BB25_DANRE", "id": "A0A8M2BB25-1", "name": "V-type proton ATPase subunit a", "aln": "------------MGELFRSEEMTLAQLFLQSESAYCCVSELGEIGMVQFRDLNPDVNAFQRKFVNEVRRCEEMDRKLRFVEKEIKKAN----------------IPIVDTG--ENPEVPFP-RDMIDLEATFEKLENELKEINTNQEALKKNFLELTELKHILRRTQQFFDE---------------------------MEDPSLLEESSTLLDPNEVGRAAP---LRLG-----------------FVAGVIGRERIPTFERMLWRVCRGNVFLRQADIEDPLEDPAT---GDNVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMAAGVNTRIDDLQMVLNQTEDHRQRVLQAAAKTVRVWFIKVRKMKAIYHTLN---LCNIDVTQKCLIAEIWCPVSDLDSIQFALRRGTERSG--------------------------------------STVPSILNRMQTKQTPPTYNKTNKFTSGFQSIVDAYGISNYREMNPAPYTIITFPFLFAVMFGDLGHGVLMTCAALYLVLRESRLIAQKN----DSEMFSMVFAGRYIILLMGLFSMYTGIIYNDCFSKSLNIFGSGWSVRPMFGEKGDNWTFAVLEKSNVLQLNPAVPNVFTG--PYPVGIDPIWNIA-TNKLTFLNSFKMKMSIILGVIHMIFGVSLSLFNHLYFRKPLNIYLGFIPEIIFMVSLFGYLVLLIFYKWIAYDAK------SSRVAPSLLITFINMCLFSYN----DPTNKPFYTGQVVIQCLLVIIALSCVPCMLIVKTLVMRRQHLWRRHLGTQNFGG-----------IHVGNGPTEDEAEIIQHDQLSQNTEEEPEPSEEEVFNFADEAVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWSMVMHMGLSSRS---FGGFIFLSIIFCFFAVLTVFILLVMEGLSAFLHALRLHWVEFQNKFYTGQGFKFMPFTFDSILD---GKSEE-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XZ10-1", "uniprot_id": "Q9XZ10_DROME", "id": "Q9XZ10-1", "name": "V-type proton ATPase subunit a", "aln": "------------MGSLFRSEEMALCQLFLQSEAAYACVSELGELGLVQFRDLNPDVNAFQRKFVNEVRRCDEMERKLRYLEKEIKKDG----------------IPMLDTG--ESPEAPQP-REMIDLEATFEKLENELREVNQNAEALKRNFLELTELKHILRKTQVFFDESVPTVYKSSGAYSSS-----KYRRYPQMADNQNEDEQAQLLGEEGVRASQPGQNLKLG-----------------FVAGVILRERLPAFERMLWRACRGNVFLRQAMIETPLEDPTN---GDQVHKSVFIIFFQGDQLKTRVKKICEGFRATLYPCPEAPADRREMAMGVMTRIEDLNTVLGQTQDHRHRVLVAAAKNLKNWFVKVRKIKAIYHTLN---LFNLDVTQKCLIAECWVPLLDIETIQLALRRGTERSG--------------------------------------SSVPPILNRMQTFENPPTYNRTNKFTKAFQALIDAYGVASYREMNPAPYTIITFPFLFAVMFGDLGHGAIMALFGLWMIRKEKGLAAQKT----DNEIWNIFFGGRYIIFLMGVFSMYTGLIYNDIFSKSLNIFGSHWHLS---------YNKSTVMENKFLQLSPKG-DYEGA--PYPFGMDPIWQVAGANKIIFHNAYKMKISIIFGVIHMIFGVVMSWHNHTYFRNRISLLYEFIPQLVFLLLLFFYMVLLMFIKWIKFAATNDKP-YSEACAPSILITFIDMVLFNTPKPPPENCETYMFMGQHFIQVLFVLVAVGCIPVMLLAKPLLIMQARK------QANVQP-----------IAGATSDAEAGGVSNSGSHGGGGGHEEEE-------ELSEIFIHQSIHTIEYVLGSVSHTASYLRLWALSLAHAQLAEVLWTMVLSIGLKQEG---PVGGIVLTCVFAFWAILTVGILVLMEGLSAFLHTLRLHWVEFQSKFYKGQGYAFQPFSFDAIIENGAAAAEE-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1ZBF7-1", "uniprot_id": "A1ZBF7_DROME", "id": "A1ZBF7-1", "name": "V-type proton ATPase subunit a", "aln": "--MRVFKKRQTKVKSFFRSEDMDLCQLLLHTENAFDCLIEVGHHGAVQFNNVYDEDRLLNNLYSKKVTQCYELLRIVDSLHTYIVQLHVN-------------EIFYPDVD----RENRLKEKDLAKYSDSLKRIHVEASAVTEHYYRLDSRRNRMMEHSFALNKANKYMVS--------------------------DMGSELLYSESTVIGLVQDATTTSGAYPAHLN-----------------YMIGCIRADKFYSFELLLYRLCSFNLIIRFSEMPSPVYEYHYGYKPERVRKFAILMMASSTMIWPKVLKICAHYHVNIYDCPSSASQREDKVKELSQEIVNVEKVLKEAELMRRQILEVAGRDLFIIRVNLRKALKVYDLMNRLRLVGGVEVPRYLLAEVYIPSSDVPEVEVILRNASRISGGADNIDSSDEDEMNDMKTMPNTTPYPIEADFQPLEDMSAGAILLKKNRLVNHMPPTYFRLNKFTRGFQNLIDAYGMADYKELNPAPYTIITFPFLFAVMFGDLGHGILLILFSSLMIWKHREIEKYQINATSENEILNILYAGRYIILLMGVFSVYMGLVYNIVMAKGFNLFGSSWSCR---------YNETTVYDPAFHVTLDSSHPHFYSGHPYPLGMDPVWAVCGQDSITTTNSLKMKMAIVLGISQMMFGLGLAAANCVLMNRKADLILVVIPQMIFMLCLFGYLVFLIFYKWMSYGGHKPAP-YNAACAPSVLITFINMMLMKKED-PVENCLDYMYPNERMIEFALVGIAFCTIPILLAGKPIYLMRRRRKMQQERERDFKR------------MRRQTIAEMRSTMRYTDDDNSETSRQKSVDNEEEHEMSEIWIHSGIHTIETVLGSVSHTASYLRLWALSLAHDQLSDVLWHMVLTKGFANTLP-LYYGVPVLMATFFAWAILTVAILVMMEGLSAFLHTLRLHWVEFQSKFFGGAGESFKAFNFPTSNQRS-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*** * *: : * : . . . . :: . :. : :: : :: * . : : : . . . : : * : . : * * : :: :*:* *::.: : : : * :: : . : :: :: : : : .: :: :: : * : : :: :* : *:.* : * :: :: * . : . . ***. : **** .** : *.**:. *:* *.. : :****:**:****:*** :: . :: . : : *: . : ***:::*** *::* *: ** ::* :.:* : * **.*:* * : : *: ***::::.* :* :. :: * . : .:* ::*: :* *: :. ** **.:* :*:* * :: : :: :: *. :* :* *.: : :.: :*. ***** *. :*:************** **:.*** *.: .: . * : :* :::.:** **:**:******* .**: * * : .* * ", "identical_positions": 140, "similar_positions": 188, "identity": "13.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3029", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62632-1", "uniprot_id": "FSTL1_RAT", "id": "Q62632-1", "name": "Follistatin-related protein 1", "aln": "----------------------------------------------------------------------------------------MWKRWLALA--LVTIALVHGEEEQRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCKPHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKKSVSPSASPVVCYQANRDELRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKSFDNGDSHLDSSEFLKFVEQNETAVNITAYPNQENNKLLRGLCVDALIELSDENADWKLSFQEFLKCLNPSFNPPEKKCALEDETYADGAETEVDCNRCVCSCGHWVCTAMTCDGK----NQKGVQTHTEEEMTRYAQELQKHQGTAEKTKKVNTKEI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62356-1", "uniprot_id": "FSTL1_MOUSE", "id": "Q62356-1", "name": "Follistatin-related protein 1", "aln": "----------------------------------------------------------------------------------------MWKRWLALS--LVTIALVHGEEEPRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCKPHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKKSASPSASPVVCYQANRDELRRRLIQWLEAEIIPDGWFSKGSNYSEILDKYFKSFDNGDSHLDSSEFLKFVEQNETAINITTYADQENNKLLRSLCVDALIELSDENADWKLSFQEFLKCLNPSFNPPEKKCALEDETYADGAETEVDCNRCVCSCGHWVCTAMTCDGK----NQKGVQTHTEEEKTGYVQELQKHQGTAEKTKKVNTKEI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12841-1", "uniprot_id": "FSTL1_HUMAN", "id": "Q12841-1", "name": "Follistatin-related protein 1", "aln": "----------------------------------------------------------------------------------------MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCKPHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKKSVSPSASPVVCYQSNRDELRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFDNGDSRLDSSEFLKFVEQNETAINITTYPDQENNKLLRGLCVDALIELSDENADWKLSFQEFLKCLNPSFNPPEKKCALEDETYADGAETEVDCNRCVCACGNWVCTAMTCDGK----NQKGAQTQTEEEMTRYVQELQKHQETAEKTKRVSTKEI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GDB1-1", "uniprot_id": "A0AC58GDB1_DANRE", "id": "A0AC58GDB1-1", "name": "Follistatin-related protein 1", "aln": "MPVISLCDCQPPALRPLLNTVDHFYPSLCSLSGSAPRLFTGHVTSRRGKKRIPERCSSFLRSHPQTYSGPRRRAFPPHRHPGGVFLQKMMFRCLPVFF-LLAVVCCHAEQEAQSKSKVCANVFCGAGRECAVNEKGEPSCLCIEQCKTHKRSVCGSNGKTYRNHCELHRDACLTGLKIQVAHDGHCKEKKKEKAAASPVVCYVADRNELRRRVIEWLQTEVVPDGWFTKGSNFTDILLKYFKNYDNGDSQLDSAELLKFIQHNETAVQMSSYAEEENNRLLRSLCVDALIELSDENADWKLSFDEFLNCLKPGFSPPEKKCALEDETYEDGAETQVECNRCVCACGNWVCTAMTCDEKTPVFDTEGDQEMTEEEWTRRVAELNKHQETVEKMK-TSTKEV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * *.: *:::. :.*:* :****:**************.*****:********.***.********* ************* **** :********. ..:******* ::*:*****:*:**::*::*****:****:::** ****.:*****:***:*:***:::****:::::*.::***:***.********************:***:**:*.*.************* *****:*:******:**:********* * : :* * **** * . **:*** *.** * ..***:", "identical_positions": 212, "similar_positions": 68, "identity": "53.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3038", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O95415-1", "uniprot_id": "BRI3_HUMAN", "id": "O95415-1", "name": "Membrane protein BRI3", "aln": "MDHKPLLQERPPAYNLEAGQGDY----ACGPHGYGAIPAAPPPPP-YPYLVTGIPTHHPRVYNIHSRTVTRYPANSIVVVGGCPVCRVGVLEDCFTFLGIFLAIILFPFGFICCFALRKRRCPNCGATFA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28662-1", "uniprot_id": "BRI3_MOUSE", "id": "P28662-1", "name": "Membrane protein BRI3", "aln": "MDHKPLLQERPPAYNLEAGQGDY----ACGPHGYGAIPTAPPPPP-YPYLVTGIPTSHPRVYNIHSRTVTRYPANSIVVVGGCPVCRVGVLEYCFTCLGIFLAIVLFPFGFLCCFALRKRRCPNCGAVFT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FAC9-1", "uniprot_id": "E7FAC9_DANRE", "id": "E7FAC9-1", "name": "Membrane protein BRI3", "aln": "MDTKPLLQDRPPAYNTVPSAYDYGSIPAAGAPAAGFQPPAPPPYQGFPAAASGYPAAPAPAAAQPAFSTYTIVQPSVVVVGGCPACRVGVLEDDFTCLGIMCAIFFFPLGILFCLALRQRRCPNCGATFG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *****:****** .. ** *.*. . * *.**** :* .:* *: . . : :. *:*******.******* ** ***: **.:**:*:: *:***:********.* ", "identical_positions": 64, "similar_positions": 27, "identity": "49.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3043", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4G005-1", "uniprot_id": "ERCC3_RAT", "id": "Q4G005-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "aln": "----MG--KRDRVDR--DKKKSKKRQYEE-EEE----DEDDAPGNESQEA--------------VPSAAGK--QVDESSTKVDEYGAKD-----------------------YR----QQMPLKGDHTSRPLWVAP-DGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTHVHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIIQFIKLCTVSYGKVKLVLKHNRYFVESSHPDVIQHLLQDPVIRECRLRNAEGEATELITETFTSKSAISKTVE-GSGGASTSQGVDAQAK------SDIPKDLFDFYEQMDKDEEEEEET--QTVSFEVKQEMIEELQKRCICLEYPLLAEYDFRNDSLNPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDK-PIGCSIAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEE-ELAFSTKEEQQQLLQKVLAATD--------LDAEEEVVAGEFG---SRSGQASRRFGTMSSLSGADDTVYMEYHSSR-NKAST-KHVHPLFKRFRK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49135-1", "uniprot_id": "ERCC3_MOUSE", "id": "P49135-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "aln": "----MG--KRDRVDR--DKKKSKKRQYEE-EEE----DEDDIPGNESQEA--------------VPSAAGK--QVDESSTKVDEYGAKD-----------------------YR----QQMPLKGDHTSRPLWVAP-DGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTHVHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIIQFIKLCTVSYGKVKLVLKHNRYFVESSHPDVIQHLLQDPVIRECRLRNAEGEATELITETFTSKSAISKTAAEGSGGPSTSQGVDAQAT------SDIPKDLFDFYEQMDKDEEEEEET--QTVSFEVKQEMIEELQKRCICLEYPLLAEYDFRNDTLNPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDK-PIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMILDEVHTIPARMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEE-ELAFSTKEEQQQLLQKVLAATD--------LDAEEEVVAGEFG---SRSGQASRRCGTMSSLSGADDTVYMEYHSSR-SKASS-KHVHPLFKRFRK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19447-1", "uniprot_id": "ERCC3_HUMAN", "id": "P19447-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "aln": "----MG--KRDRADR--DKKKSRKRHYED-EED----DEEDAPGNDPQEA--------------VPSAAGK--QVDESGTKVDEYGAKD-----------------------YR----LQMPLKDDHTSRPLWVAP-DGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTHVHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQFIKLCTVSYGKVKLVLKHNRYFVESCHPDVIQHLLQDPVIRECRLRNSEGEATELITETFTSKSAISKTAE-SSGGPSTSRVTDPQGK------SDIPMDLFDFYEQMDKDEEEEEET--QTVSFEVKQEMIEELQKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDK-PIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEE-DLAFSTKEEQQQLLQKVLAATD--------LDAEEEVVAGEFG---SRSSQASRRFGTMSSMSGADDTVYMEYHSSR-SKAPS-KHVHPLFKRFRK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVV1-1", "uniprot_id": "ERCC3_DANRE", "id": "Q7ZVV1-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "aln": "----MG--RKDKSDR--EKK-SKKRYYED-EEE----DEE-VIGGESQEA--------------VPAAAGK--QVDESSTKLDEYGAKD-----------------------YR----LQMLLKNDHSSRPLWVAP-DGHIFLEAFSPVYKYAQDFLVAISEPVCRPTHAHEYKLTAYSLYAAVSVGLQTSDIIEYLQKLSKTSVPDGIVQFIKLCTVSYGKVKLVLKHNRYFVESAFPDVIQRLLQDTVIRDCRLRSAEGEETELITETISSKSAISKSQQ-DNGGPSSSQPADGQRSG-----TQVPEDIFSYYEQMDKEEEEEEET--QTVSFEIRQEMIEELQKRCIQLEYPLLAEYDFRNDTVNPDINMDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSSVSVEQWKAQFKMWSTIDDSQICRFTSDAKDK-PIGCSVAISTYSMLGHTTKRSWEAERVMEWMKSQEWGLIILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIRFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAYFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEE-DLMFSTRDEQQQLLQKVLAASD--------LDAEEEVVMGEVG---GKP-QFSRRAGTMSSMSGADDALYMEYQMPRGSKASVGKNIHPLFKRFRK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02870-1", "uniprot_id": "ERCC3_DROME", "id": "Q02870-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "aln": "----MGPPKKSRKDRSGGDKFGKKRRAED-EAFTQLVDDNDSLDATESEG--------------IPGAASKNAETNDEQINTDEYGAKD-----------------------YR----SQMQLRPDHGNRPLWVAP-NGHVFLESFSPVYKHAHDFLIAISEPVCRPEHIHEYKLTAYSLYAAVSVGLQTHDIVEYLKRLSKTSIPEGILEFIRLCTLSYGKVKLVLKHNKYFIESPHPEVLQKLLKDPVIQKCRLIRSEGE--DFIQGTLDGK-AITQFGTKLPPGATDKPTPDPAAAAGADGTTAVPEDITDFYEKIDKEEEDEDEANLKTVSFEVAQEKIEVIQKRCIEIEHPLLAEYDFRNDTNNPDINIDLKPAAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTACCTVRKRALVLCNSGVSVEQWKQQFKMWSTADDSMICRFTSEAKDK-PMGCGILVTTYSMITHTQKRSWEAEQTMRWLQEQEWGIMVLDEVHTIPAKMFRRVLTIVQSHCKLGLTATLLREDDKIADLNFLIGPKLYEANWLELQKKGYIARVQCAEVWCPMSPEFYREYLTTKTSKKMLLYVMNPSKFRSCQFLIKYHEQRGDKTIVFSDNVFALKHYAIKMNKPFIYGPTSQNERIQILQNFKFNSKVNTIFVSKVADTSFDLPEANVLIQISSHGGSRRQEAQRLGRILRAKKGAIAEEYNAFFYTLVSQDTMEMSYSRKRQRFLVNQGYSYKVITHLKGMDTDSDLMYGTQEEQGQLLQLVLSASD--------LDCEDEKLPGEPGYRPSGSGGAVRRVGGLSSMSGGDDAIYYEHRKKN------IGSVHPLFKKFRG-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q00578-1", "uniprot_id": "RAD25_YEAST", "id": "Q00578-1", "name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2", "aln": "MTDVEGYQPKSKGKIFPDMGESFFSSDEDSPATDAEIDENYDDNRETSEGRGERDTGAMVTGLKKPRKKTKSSRHTAADSSMNQMDAKDKALLQDTNSDIPADFVPDSVSGMFRSHDFSYLRLRPDHASRPLWISPSDGRIILESFSPLAEQAQDFLVTIAEPISRPSHIHEYKITAYSLYAAVSVGLETDDIISVLDRLSKVPVAESIINFIKGATISYGKVKLVIKHNRYFVETTQADILQMLLNDSVIGPLRIDS--------DHQVQPPEDVLQQQLQQTAGKPATNVNPNDVEA------------VFSAVIGGDNEREEEDDDIDAVHSFEIANESVEVVKKRCQEIDYPVLEEYDFRNDHRNPDLDIDLKPSTQIRPYQEKSLSKMFGNGRARSGIIVLPCGAGKTLVGITAACTIKKSVIVLCTSSVSVMQWRQQFLQWCTLQPENCAVFTSDNKEMFQTESGLVVSTYSMVANTRNRSHDSQKVMDFLTGREWGFIILDEVHVVPAAMFRRVVSTIAAHAKLGLTATLVREDDKIGDLNFLIGPKLYEANWMELSQKGHIANVQCAEVWCPMTAEFYQEYLRETARKRMLLYIMNPTKFQACQFLIQYHERRGDKIIVFSDNVYALQEYALKMGKPFIYGSTPQQERMNILQNFQYNDQINTIFLSKVGDTSIDLPEATCLIQISSHYGSRRQEAQRLGRILRAKR-RNDEGFNAFFYSLVSKDTQEMYYSTKRQAFLVDQGYAFKVITHLHGMENIPNLAYASPRERRELLQEVLLKNEEAAGIEVGDDADNSVGRGSNG-HKRFKSKAVRGEGSLSGLAGGEDMAYMEYSTNK---NKELKEHHPLIRKMYYKNLKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :.: . . *: *:: . .*. * * . . :: .*** :* : *: ** .****::* :*:::**:***: : *:***::*:**:.** * ****:*************:* ** . * :***. :.:.*::**: .*:********:***:**:*: .:::* **:*.** *: . : .: : .: . : : . *::.*:*:: . ***: :* :* ::*** :::*:* ******* ***:::****:: :******** ***********:*********:***:**.**::* :** .*.*** **: ** *.* : . . ***: *: ..: ::****: :* :** ::::.* :: :***:::*****.:** *****:: : :*.********:****** ***************:**.::*:**.**********:.***:**: .: *::*** ***.**::*****::**:*.** ***:***:**:.**:::.**:***.*.* **::*****:.* ::****:***.***:*****. ******* ************:****: * :**:**:***:** ** ** *** ***:***::****:* **: :* :.: *: :*** ** .: *.::. *. * * * :*.::*.:* * *: . ***:::: ", "identical_positions": 367, "similar_positions": 214, "identity": "42.28%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-305", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O95229-1", "uniprot_id": "ZWINT_HUMAN", "id": "O95229-1", "name": "Outer kinetochore KNL1 complex subunit ZWINT", "aln": "-----MEAAETEAEAAALEVLAEVAGILEPVGLQEEAELPAKILVEFVVDSQKKDKLLCSQLQVADFLQNILAQEDTAKGLDPLASEDTSRQKAIAAKEQWKELKATYREHVEAIKIGLTKALTQMEEAQRKRTQLREAFEQLQAKKQMAMEKRRAVQN-------QWQLQQEKHLQHLAEVSAEVRERKTGTQQELDRVFQKL------------------------------------------------------------------------------GNLKQQAEQERDKLQRYQT---FLQLLYTLQGKLLFPEAEAEAENLPDDKPQQPTRPQEQSTGDTMGRDPGVSFKAVG-LQPAGDVNLP-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YXM6-1", "uniprot_id": "A0A8M6YXM6_DANRE", "id": "A0A8M6YXM6-1", "name": "", "aln": "MATERVEAISLHGTTSLLLERTDLSSSKSCNTTELQETGEGEIMVPYLMDCRRKQKQVFRQLFVVDDMIQLLAGLES---VDQLLDEPCPQNPGNGARSAWKTLKAEYQEKVEEMEGLISTLQIRMEELQAKRQTLNSLLSTLEMKKEECKEKERITAKQNQRAEKQISFQLEDSLQAAQNAMHLCDGQLSKLKDEIEKRQARINDWTLLRDGLQSLVTMTHKGMQYRLLSVSPSELCLELLTHAGEKPLEPLRVTITMTTKDEFHLQVLQGTAGLVEEAMNGPLRQVSVALEEVMEKYISQGEMLSEIQSLRARYAIDWCPAEKLLIFLKTATKVCHLRVEEGYPSHGRAVLLSVRKDGNLLDINDLQPPVQHPVLTEWLEFLSSNPNI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** . .. :: * ::::. . : : .:*:* :::*.::*:* : ** *.* : ::** :: :* * .* .:: . .*:. ** *** *:*:** :: ::. :*** * ** *.. :. *: **: . **.* . : * .:* *. ** :. : : ::*::: :: * *:* : .: :::* : :*. : :*:.: : . ** : ... : : : :. : ** :*.: * * .*:: * ", "identical_positions": 61, "similar_positions": 105, "identity": "15.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3055", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UJD6-1", "uniprot_id": "UBP19_MOUSE", "id": "Q3UJD6-1", "name": "Ubiquitin carboxyl-terminal hydrolase 19", "aln": "---MSAGASATGPRRGPPGLEEATS--KKKQKDRANLESKDGDARR-----------------------------------------------VSLPRKEPTKD---------------ELLLDWRQSADEVIVKLRVG-TGPVRLEDVDAAFTDTDCVVRLPDGRQWGGVFFAEIQSSCTKVQAR---KGGLLQLVLPKKVPLLTWPSLLK-----PLGTQELVPGLQCQENGQELSPIALEPGSEPRRAKQEARNQKRAQGRGEVG-----------------SGAGPGTQAGPSAKRAVH-------------LRRGPEGEGSMDGPGPQGDAPSFLSDSATQVEAEEKLCAPPMNTQTS--------------LLSSEKSLALLTVEKTVS----------------------------PRNDPVAPVMVQDRDPEP-------------------EQEDQVKEEMALGADPTALVEEPESMVNLAFVKNDSYEKGPDSVVVHVYVKEIRRDSSRVLFREQDFTLIFQTRDGNFLRLHPGCGPHTIFRWQVKLRNLIEPEQCTFCFT--ASRIDICLRKRQSQRWGGLEAPATRGAVGGAKVAVPTGPTPLDSTPPGGGPHPLTGQEEARAVE---KEKPKARSEDSGLDGVVARTPLEHVAPKPDPHLASPKPTCMVPPMPHSPVS--GDSVEEDEEEEKKVCLPGFTGLVNLGNTCFMNSVIQSLSNTRELRDFFHDRSFEAEINYNNPLGTGGRLAIGFAVLLRALWKG--------THQAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDGRPD-------EVVAEEAWQRHKMRNDSFIVDLFQGQYKSKLVCPVCAKVSITFDPFLYLPVPLPQKQKVLPIFYFAREPHSKPIKFLVSVSKENSSASEVLDSLSQSVHVKPENLRLAEVIKNRFHRVFLPSHS-------LDAVSPTDVLLCFELLSPELAKERVVVLEVQQRPQVPSIPISKCAACQRKQQSEEEKLKRCTRCYRVGYCNQFCQKTHWPDHKGLCRP--------ENIGYPFLVSVPASRLTYARLAQLLEGYARYSVSVFQPPFQPGRMALESQSPGCTTLLSTSSLEAGDSEREPIQPSELQLVTPVAEGDTGAHRVWPPADRGPVPSTSGLSSEMLASGPIEGCPLLAGER----VSRPEAAVPGYQHSSESVNTHTPQFFIYKIDASNRE-QRLEDKGETPLELGDDCSLALVWR------NNERLQEFVLVASKELECAEDPGSAGEAARAGHFTLDQCLNLFTRPEVLAPEEAWYCPQCKQHREASKQLLLWRLPNVLIVQLKRFSFRS-----FIWRDKINDLVEFPVRNLDLSKFCIGQK--EEQLP--SYDLYAVINHYGGMIGGHYTACARLPNDRSSQRSDVGWRLFDDSTVTTVDE-SQVVTRYAYVLFYRRRNSPVERPPRASHSEHHPDLGP-----------------AAEAAASQASRIWQELEAEEEMVPEG-------PGPLGPWG---PQDWVGPPPRG----------PTTPDEGCLRYFVLGTVAALVALVLNVFYPLVSQSRWR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6J1Y9-1", "uniprot_id": "UBP19_RAT", "id": "Q6J1Y9-1", "name": "Ubiquitin carboxyl-terminal hydrolase 19", "aln": "---MSAGTSATGPRRGPPGLEEATS--KKKQKDRANQESKDGDPRR-----------------------------------------------VSMPRKEPTKD---------------ELLLDWRQSSDKVVVKLRVG-TGPICLEEVDAAFTDTDCVVRLPDGRQWGGVFFAKIQSSCTKVQTR---KGGLLQLALPKKVPLLTWPSLLKK----PLGTQELVPGLRCQENGQELSPIALEPGSEPRRAKQEARNQKRAQGRGEVG-----------------SGASPGAQAGPSAKRAVH-------------LCRGPEGEGSMDGPGPQGDAPSFLSDSATQVEAEEQLHVPPVNPQTS--------------LLGSEKNLALLTVEKTVS----------------------------PRSDSVSPVMIRNRDPE---------------------KDDHFKEEMAVGADPAALADEPESMVNLAFVKNDSYEKGPDSVVVHVYVKESRRDTSRVLFREQDFTLIFQTRDGNFLRLHPGCGPHTIFRWQVKLRNLIEPEQCTFCFT--ASRIDICLRKRQSQRWGGLEAPATR--VGGAKVAVPTGPTPLDSTPPGGGPLPLTGQEEARAVE---KEKPKARSEDSGLDGVVARTPLEHVTPKPEPHLASPKPTCMVPPMPHSPVS--GDSVEEDEEEEKKVCLPGFTGLVNLGNTCFMNSVIQSLSNTRELRDFFHDRSFEAEINYNNPLGTGGRLAIGFAVLLRALWKG--------THQAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDGRPD-------EVVAEEAWQRHKMRNDSFIVDLFQGQYKSKLVCPVCAKVSITFDPFLYLPVPLPQKQKVLPIYYFAREPHSKPIKFLVSVSKENSSASEVLESLSQSVHVKPESLRLAEVIKNRFHRVFLPSHS-------LDAVSPTDVLLCFELLSPELAKERVVVLEVQQRPQVPSIPISKCAACQRKQQSEDEKLKRCTRCYRVGYCNQFCQKTHWPDHKGLCRP--------ENIGYPFLVSVPASRLTYARLAQLLEGYARYSVSVFQPPFQPGRMALESQSPGCTTLLSTSSLEAGDSEREPIQPSELQLVTPVAEGDTGAHRMWPPADRGPVPSTSGISSEMLASGPMEGCSLLAGER----VSRPEAAVPGYQHSRESVSAHTPQFFIYKIDASSRE-QRLEDKGDTPLELGDDCSLALVWR------NNERLQEFVLVASKELECAEDPGSAGEAARAGHFTLDQCLNLFTRPEVLAPEEAWYCPQCKQHREASKQLLLWRLPNVLIVQLKRFSFRS-----FIWRDKINDLVEFPVRNLDLSKFCIGQK--EEQLP--SYDLYAVINHYGGMIGGHYTACARLPSDRSSQRSDVGWRLFDDSTVTTVDE-SQVVTRYAYVLFYRRRNSPVERPPRAAHAEHHPDLGP-----------------AAEAAASQASRIWQELEAEEEMVPEG-------PGPLGPWG---PQDWVGPPPRG----------PTTSDEGCLRYFVLGTVAALVALVLNVFYPLVSQSRWR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O94966-1", "uniprot_id": "UBP19_HUMAN", "id": "O94966-1", "name": "Ubiquitin carboxyl-terminal hydrolase 19", "aln": "---MSGGASATGPRRGPPGLEDTTS--KKKQKDRANQESKDGDPRKETGSRYVAQAGLEPLASGDPSASASHAAGITGSRHRTRLFFPSSSGSASTPQEEQTKEGACEDPHDLLATPTPELLLDWRQSAEEVIVKLRVG-VGPLQLEDVDAAFTDTDCVVRFAGGQQWGGVFYAEIKSSCAKVQTR---KGSLLHLTLPKKVPMLTWPSLLV---------------------------------------------------------------------------------------------------------------------------------------EADEQLCIPPLNSQTC--------------LLGSEENLAPLAGEKAVP----------------------------PGNDPVSPAMVRSRNPG---------------------KDDCAKEEMAVAADAATLVDEPESMVNLAFVKNDSYEKGPDSVVVHVYVKEICRDTSRVLFREQDFTLIFQTRDGNFLRLHPGCGPHTTFRWQVKLRNLIEPEQCTFCFT--ASRIDICLRKRQSQRWGGLEAPAAR--VGGAKVAVPTGPTPLDSTPPGGAPHPLTGQEEARAVE---KDKSKARSEDTGLDSVATRTPMEHVTPKPETHLASPKPTCMVPPMPHSPVS--GDSVEEEEEEEKKVCLPGFTGLVNLGNTCFMNSVIQSLSNTRELRDFFHDRSFEAEINYNNPLGTGGRLAIGFAVLLRALWKG--------THHAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDGRPD-------EVVAEEAWQRHKMRNDSFIVDLFQGQYKSKLVCPVCAKVSITFDPFLYLPVPLPQKQKVLPVFYFAREPHSKPIKFLVSVSKENSTASEVLDSLSQSVHVKPENLRLAEVIKNRFHRVFLPSHS-------LDTVSPSDTLLCFELLSSELAKERVVVLEVQQRPQVPSVPISKCAACQRKQQSEDEKLKRCTRCYRVGYCNQLCQKTHWPDHKGLCRP--------ENIGYPFLVSVPASRLTYARLAQLLEGYARYSVSVFQPPFQPGRMALESQSPGCTTLLSTGSLEAGDSERDPIQPPELQLVTPMAEGDTGLPRVWAAPDRGPVPSTSGISSEMLASGPIEVGSLPAGER----VSRPEAAVPGYQHPSEAMNAHTPQFFIYKIDSSNRE-QRLEDKGDTPLELGDDCSLALVWR------NNERLQEFVLVASKELECAEDPGSAGEAARAGHFTLDQCLNLFTRPEVLAPEEAWYCPQCKQHREASKQLLLWRLPNVLIVQLKRFSFRS-----FIWRDKINDLVEFPVRNLDLSKFCIGQK--EEQLP--SYDLYAVINHYGGMIGGHYTACARLPNDRSSQRSDVGWRLFDDSTVTTVDE-SQVVTRYAYVLFYRRRNSPVERPPRAGHSEHHPDLGP-----------------AAEAAASQASRIWQELEAEEEPVPEG-------SGPLGPWG---PQDWVGPLPRG----------PTTPDEGCLRYFVLGTVAALVALVLNVFYPLVSQSRWR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B997-1", "uniprot_id": "A0A8M2B997_DANRE", "id": "A0A8M2B997-1", "name": "ubiquitinyl hydrolase 1", "aln": "MASSSTGSSESGRRRGQRGPDDTVSTSKKKQKDRANQESKEAKR---------------------------------------------------VATSTETKK---------------DLFLDWKQNAYEVIVRLNCGGAGVLRVEDIEYDFSNSACHIRLPDGREWSCHLHEEIEASCSKLNYKE--KSNVLQLVMHKKIPLNTWPAYAKKSEPVDILQKNGSNNYQSSTGRSEKSSEAIEKTPPVSSAEQKRGKPDRGLKRGMKGKQVHVTESTGEKTPEIKSSDKADSINEPSAKRTTRPSKNTKEPPLAPCLGNESKSKATVNGKTHTSEVNSGASSSSNAKDNRAQMQGKPQGCQALQKEKGIDRKPKSNAQVGSGESKSVSVCEPQVPQKEHSSPVKTCTDKIASDEPENRKEETKPQAEGHIPKMLPSHDLGSGEPASTDFKSEESPQKSQTEEKRDKSKEEPQGASQEEDTEGPEPMVDLKFVKNDSYEKGTDLMVVNVYMKEICRQTSRVLFREQDFTLIFQTSDPNFLRLHSDCGPNTVFKWQVKLRNLIQPDQSNYAFT--PSRIDITLKKRHSQRWGGLEAPATQGAVGGAKVAVASSPSTLEKSQPGSSQHALPAKEEPRVGEE--KPKPPRAPEDSGLDAVSPRSVSEHVSLKQEPAVATPKPTCMVQPMTHTPPV--GNERSE-EVEEKKVCHPGFTGLVNLGNTCFMNSVIQSLSNTRELRDYFHDRGFESEINCNNPLGTGGRLAIGFAVLLRALWKG--------THHAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDGRQD-------EVVAEEAWQRHKMRNDSFIVDLFQGQYKSKLVCPMCSKVSITFDPFLYLPVPLPQKQKVLTVFYFAKEPHKKPVKFLVSVSKESSSTAEVLESISRSVRIKPENLRLTEVVKGRFHRIFLPSQS-------LDTVSSSDLLFCFEMLSKDLIKERVVLLKVQQRPQIPSIPITKCAGCLKPPASDDEKLKRCTRCYRVGYCNQTCQKNHWPSHKTMCRSNV------ENIGQPFLISVPESRLSYTRLTQLLEGYSRYSVNVFQPPFQSGRTSPES-SLSRVDLTSMASSVPECQEKDLPSAGDAENPAEQDESVT-ASQTESAADGGDTLSTHTTDSGCCELASSSHDSLLEKETSCEKAVKPEAVVTGYQQPSESASGGASQFYITILDSSQKEDKKLEEKGDAVLELPDECTLELVWK------NNERQKEYVLVRSKDLEFDEDPGSATETSRAGHFTLEQCLNLFTKPEVLAPEEAWYCPKCQQHREASKQLLLWRLPNVLIIQLKRFSFRS-----FIWRDKINDMVDFPVRNLDLSKFCIGHKGDIQQPP--IYDLYAVINHYGGMIGGHYTAYARLPSDKNSQLSDVGWRLFDDSTVTTVEE-SQVVTRYAYVLFYRRRNSPVERPS-HLLGPLGAESSA-----------------ATGGAASQASLIWQELEEDEEGQREASFRSLFRPGLRGRRARMRPEQEEEEEGRGGLSHRRRDDNSDYSDGERMRYFILGTVAAILALLFNLIYPLLYWSNWV---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P39944-1", "uniprot_id": "UBP5_YEAST", "id": "P39944-1", "name": "Ubiquitin carboxyl-terminal hydrolase 5", "aln": "----------MGSEQALSEVVESAKERFGRLRHLVQKFLDDDDVPQ-------------------------------------------------------------------------ECLPLLQECAEIWSSYVDACQDITMQAPKEDANRLSKGFLRLNETAFLYYMIVYTLLEDTLPRLKEFSSNKDQNVRNLYGERIQLLHNDPNIER------------------------------------------------------------------------------------------------------------------------------IRNVIENYPKFIQLQTIEPGKLSS-------------MLHFHGDALLLIDVRPRSE----------------------------FVRAHIKCKNIICIDPAS--------------FKDSFTDQQIESVSLITSPHSDITFFSNRDKFKFIILYTDTQLHNNFQQRQTRILAKILSQNSVIKPLSGTKILILENGFSNWVKLGGAYQSSVSETAHLTSSSSTPAFGSPQVPTGLFNQKSLSPNKDKSMPMVSMNTQPLLTTVQRPQLPLYYSDLPIIPQPSPNRNSPTVQKFSPHPPTT--LSKLNTPSTIQNKANTVERISPDIRAAQAHAYLP-PASNVFSPRIPPLPQQNLSSSRQTILNNSQVLDLDLIVGLENIGNCCYMNCILQCLVGTHDLVRMFLDNTYLNFINFDSSRGSKGLLAKNFAILVNNMHRHGAFTPPNVRTIPVQTIQFKKICGHINPMYSDSMQQDCQEFCQFLLDGLHEDLNQNGSKKHLKQLSDEEERMREKM-SIRKASALEWERFLLTDFSAIIDLFQGQYASRLQCQVCEHTSTTYQTFSVLSVPVP-------------------------------------------------------------------------------------------------------------------------------------RVKTCN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILDCFREFTKCERLGVDEQWSCPKCLKKQPSTKQLKITRLPKKLIINLKRFDNQMNKNNVFVQYPYSLDLTPYWARDFNHEAIVNEDIPTRGQVPPFRYRLYGVACHSGSLYGGHYTSYVYKGPKK-------GWYFFDDSLYRPITFSTEFITPSAYVLFYERIF-----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39538-1", "uniprot_id": "UBP12_YEAST", "id": "P39538-1", "name": "Ubiquitin carboxyl-terminal hydrolase 12", "aln": "----------MGSSDVSSRECSLVYNEDPDFTDGTTPCDRLG----------------------------------------------------------------------------VDLMNVLDDKDEIKQESVPVS------DREIEDTESDASAVSSFASANELIAEPHAASETNLGTNGQDG-------RNVLEQQRDVVAR---------------------------------------------------------------------------------------------------------------------------------------------------LIEENKETQ-----------------KEGDKVCIVPKVWYD------------------------------------------------------------------KFFDPDVTDPEDIGPINTRMICRDFENFVLEDYNRCPYLSIAEPVFNFLSEIYGMTSGSYPVVTNLVINQTTG-----ELETEYN-----KWFFRLHYLTEKQ----------DGRKRRHGQDDSIMYLSMSALNLVRDLVEKSMNLFFEKADHLDVNAVDFKIWFVSEGSDIATDSNVSTFLNSSYEITPLQFLELPIKKLLIPDMFENRLDKITSNPSDLVIEIKPIEGNHHWPSNYFAYNKLEPASGTTGLVNLGNTCYMNSALQCLVHIPQLRDYFLYDGYEDEINEENPLGYHGYVARAFSDLVQKLFQN--RMSIMQRNAAFPPSMFKSTIGHFNSMFSGYMQQDSQEFLAFLLDSLHEDLNRIIKKEYTEKPSLSPGDDVNDWNVVKKLADDTWEMHLKRNCSVITDLFVGMYKSTLYCPECQNVSITFDPYNDVTLPLP--VDTVWDKTIKIFPMNSPPLLLEVELSKSSTYMDLKNYVGKMSGLDPNTLFGCEIFSNQIYVNYESTESNAQFLTLQELIKPADDVIFYELPVTNDNEVIVPVLNTRIEKGYKNAMLFGVPFFITLKEDELNNPGAIRMKLQNRFVHLSGGYIPFPEPVGNRTDFADAFPLLVEKYPDVEFEQYKDILQYTSIKVTDKDKSFFSIKILSVEKEQQFASNNRTGPNFWTPISQLNLDKATDIDDKLEDVVKDIYNYSSLVDCAEGVLMQVDDEGDTEGSEAKNFSKPFQSGDDEENKETVTNNENVNNTNDRDEDMELTDDVEEDASTEPELTDKPEALDKIKDSLTSTPFAILSMNDIIVCEWSELGSNEAFSDDKIYNWENPATLPNKELENAKLERSNAKERTITLDDCLQLFSKPEILGLTDSWYCPTCKEHRQATKQIQLWNTPDILLIHLKRFESQR------SFSDKIDATVNFPITDLDLSRYVVYKD----DPRGLIYDLYAVDNHYGGLGGGHYTAYVKNFADN-------KWYYFDDSRVTETAP-ENSIAGSAYLLFYIRRHKDGNGLGSSKLQEIIQKSRHGYDERIKKIYDEQMKLYEFNKTDEEEDVSDDMIECNEDVQAPEYSNRSLEVGHIETQDCNDEDDNDDGERTNSGRRKLRLLKKVYKNNSGLGSSSTSEISEGCPENEVADLNLKNGVTLESPE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . . . : : : : . : . . . : . : :: : . : . . . . .: : : : : .* : . .* . . . : .* .:.: : .: : . . : . . . : .. : * . .: .** *:** *:**. :*.* :* * : ** :.. * * :* *: *:. : : .. . :* . . ::. *:*.*** ****.******: .* : : . . . : *: . : * * *** * * * * * * :.* *::.: :.:*:* . : :*:. *:: * *. : * ** * ::: ::**: : . *. *:::****. : . : ::: . . : * **.* * *.: *****: . .. * **** : :: **:*** * ", "identical_positions": 95, "similar_positions": 153, "identity": "5.85%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-306", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6DKG0-1", "uniprot_id": "NAA35_RAT", "id": "Q6DKG0-1", "name": "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "aln": "-------------MVMKAAVDD--------------------DASGWELNVP------------------EKMEKSSTSWVDITQDFEDACRELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFEQAVKDGTIKIKDLSLPELIGIMDTCFCCLITWLEG-HSLAQTVFTCLYIH-----------------NPDFIEDPAMKAFALGILKICDIAREKVNKAAVFEEEDFQSMT-YGFKMANGVTDLRVTGMLKDVEDDMQRRVKSTRSRQGEERDPEVELEHQQCLAAFSRVKFTRVLLTVLIAFTKKET----SAVAEAQKLMVQAADLLSAIHTSLHHGIQAQNGTTKGDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVNYFSRLIDRIKTVCEVVNLPNLHCILDFFCEFSEQS-PCVLSRSLLQTTFLVDNKKVFGTHLMQDMVKDALRSFVSPPVLSPKCCLYNNHQAKDCIDSFVTHCVRP--FCSLVQIHGHNRARQRDKLGHILEEFATLQDEAEKVDAALHTMLLK-----QEPQR---QHLACLGTWVLYHSLRIMIQYLLSGFELELYSMHEYYYIYWYLS---EFLYAWLMSTLSRADGSQMAEERIMEEQQKGRS-------------------SKKTKKKKKVRPLSREITMSQAYQNMCAGMFKTMVAFDMDGKVRKPKFELDSEQVRYEHRFAPFNSVMTPPPVHYLQFKEMSDLSKYSPPPQPPELYVAASKHFQQAKM---------ILESIPNADRE-----------------VSRILKVAKPNFVVMKLLAGGHKKESKVPPEFDFSVH--------KYFPVVKLV-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PHQ8-1", "uniprot_id": "NAA35_MOUSE", "id": "Q6PHQ8-1", "name": "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "aln": "-------------MVMKATVDD--------------------DASGWELGVP------------------EKMEKSSTSWVDITQDFEDACRELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFEQAIKDGTIKIKDLSLPELIGIMDTCFCCLITWLEG-HSLAQTVFTCLYIH-----------------NPDFIEDPAMKAFALGILKICDIAREKVNKAAVFEEEDFQSMT-YGFKMANSVTDLRVTGMLKDVEDDLQRRVKSTRSRQGEERDPEVELEHQQCLAAFSRVKFTRVLLTVLIAFTKKET----SAVAEAQKLMVQAADLLSAIHTSLHHGIQAQNGTTKGDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVNYFSRLIDRIKTVCEVVNLPNLHCILDFFCEFSEQS-PCVLSRSLLQTTFLVDNKKVFGTHLMQDMVKDALRSFVSPPVLSPKCCLYNNHQAKDCIDSFVTHCVRP--FCSLVQIHGHNRARQRDKLGHILEEFATLQDEAEKVDAALHTMLLK-----QEPQR---QHLACLGTWVLYHNLRIMIQYLLSGFELELYSMHEYYYIYWYLS---EFLYAWLMSTLSRADGSQMAEERIMEEQQKGRS-------------------SKKTKKKKKVRPLSREITMSQAYQNMCAGMFKTMVAFDMDGKVRKPKFELDSEQVRYEHRFAPFNSVMTPPPVHYLQFKEMSDLNKYSPPPQSPELYVAASKHFQQAKM---------ILENIPNPDRE-----------------VSRILKVAKPNFVVMKLLAGGHKKESKVPPEFDFSVH--------KYFPVVKLV-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VZE5-1", "uniprot_id": "NAA35_HUMAN", "id": "Q5VZE5-1", "name": "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "aln": "-------------MVMKASVDD--------------------DDSGWELSMP------------------EKMEKSNTNWVDITQDFEEACRELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFEQAIKDGTIKIKDLTLPELIGIMDTCFCCLITWLEG-HSLAQTVFTCLYIH-----------------NPDFIEDPAMKAFALGILKICDIAREKVNKAAVFEEEDFQSMT-YGFKMANSVTDLRVTGMLKDVEDDMQRRVKSTRSRQGEERDPEVELEHQQCLAVFSRVKFTRVLLTVLIAFTKKET----SAVAEAQKLMVQAADLLSAIHNSLHHGIQAQNDTTKGDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVNYFARLIDRIKTVCEVVNLTNLHCILDFFCEFSEQS-PCVLSRSLLQTTFLVDNKKVFGTHLMQDMVKDALRSFVSPPVLSPKCYLYNNHQAKDCIDSFVTHCVRP--FCSLIQIHGHNRARQRDKLGHILEEFATLQDEAEKVDAALHTMLLK-----QEPQR---QHLACLGTWVLYHNLRIMIQYLLSGFELELYSMHEYYYIYWYLS---EFLYAWLMSTLSRADGSQMAEERIMEEQQKGRS-------------------SKKTKKKKKVRPLSREITMSQAYQNMCAGMFKTMVAFDMDGKVRKPKFELDSEQVRYEHRFAPFNSVMTPPPVHYLQFKEMSDLNKYSPPPQSPELYVAASKHFQQAKM---------ILENIPNPDHE-----------------VNRILKVAKPNFVVMKLLAGGHKKESKVPPEFDFSAH--------KYFPVVKLV-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T322-1", "uniprot_id": "NAA35_DANRE", "id": "Q7T322-1", "name": "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "aln": "-------------MVMKSSVEE--------------------EEGGWGLGIP------------------EKMRN-NANWVDVTQEFKGACKELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFDQAVKDEAIRVKDLSIPELIGIMDTCFCCLITWLEG-HSLAQTVFTCLYVH-----------------NPDLIQDPALKAFALGILKICDIAREKVNKAAVFEEEDFQAMT-YGFKMANNVTDLRVTGMLKDVEDELQRKVKSTRSRQGEQRDPEVELDHQQCLALFSRVKFTRLLLSALISFTKKET----SAVSEAQKLMSQAADLLPAVHATIQYGIQSQNDTTKGDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVNYFSKLIERIKSVCEVINITNLHSILDFFCEFSEQS-PCVLSRSLLQTTFLIDNKKVFGTHLMQDMIKDALRCFVSPPVLSSKCSLNNNHQAKDYIDSFVTHCTRP--FCSLIQIHGHNRARQRDKLGHILEEFATLQDEAEKVDAALHGLLMK-----LEPQR---QHLACLGTWILYHNLRIMIQYLLSGFELELYSMHEYYYIYWYLS---EFLYAWLMSTLSRADSSQMAEERILEEQLKVRS-------------------SKKSKKKKKARPLSKEITMSQAYQNMCAGMYKTMIALDMDRKVRKPQFELDSEQVRYEHRFAPFNSVVTPPPVHYIQFKEMSDLKKYNPPPRSADLYMAASKHFQQAKL---------LLENVTSPDAE-----------------VNRILKVAKPNIVVMKLLAGGHKKETKALPEFDFSAH--------KYFPIVKIL-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1A2-1", "uniprot_id": "NAA35_DROME", "id": "Q9W1A2-1", "name": "N-alpha-acetyltransferase 35, NatC auxiliary subunit homolog", "aln": "MYPSTLPAEADPSTMNGSSVAEPPDFQAATAAAAAAARASSLEQDEWSVGECGFLDPDVQRTMRSGSAAEDITQYPMHGWVDVTKEFHDACAELQPGELAQDMLFGLFEAMSAIEIMDPKMDVGMGFDKQDLPPPSFEAAIATGAIKLDDLTPSELIGIYDALFSCLVSWLEG-NSMDQVLFTCLYLH-----------------APAQIKDKALRVFCTAVRNLIVVIKKIIAVAAVNEEEDFQLYGNSALLAAEKAQPATVYSSLKDVEDELIRKCKKLTS-------------TEDWMAVVHRLRFMRHLFQVIYHVEQMASNDTVDDKVDIYKILLVASEMLPGIRNTLDRGTQPEKGS---DAPNPMGFSPRIHDRSQPPAFPRSIKIRDRPSSYQFLEEMISRFKYACKVTKYKDYYSALNFFIEYSKKSGQCILSRSVLQTLFSANMRMAHGKLPMKQFLRHSVQVFNSPPVLNAKHPVAADPKVQQHLENFFRYCINMNTFTQFIRICGFNRARQRDKLARLIENFDTIQVDAARLDSMMNQLANERAMEGNEPMATALKHSTHFSTWVLYNCFRAMLIFLMSGFELELYAVHEFLYIYWYPY---EFLIGFLVSALTRTENILLAQEEYAEHQSKTQSGGSGA--------AKNRKAAKPKKNKKTQRPYRAEIVFYHALLSLCGGMYKAMGALTKDGRVRLPLSKFDNEEIRYNRRFLPFATLTSPPPVSYAEFKNVREHMMRHS---VEDLYTYAAKHFDQARN---------VLESIQNPDQE-----------------MLDLLQIARTNFVVMNVLARGHQKEVKRQPEFDFSKH--------SYFPIIKLK-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02197-1", "uniprot_id": "NAA35_YEAST", "id": "Q02197-1", "name": "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "aln": "-------------MEVDSILGS------------------------------------------------LSITDDFDQLVDVTSLFDELCSKLKPEAIVKDPRFDLFEGTHSLEVNNSKLDSSLIELTAEEIEFDVNVAYDP--------PLASVAAIADRLLRCVISWLNDYQTLPTTVLSCRYTESLLSSLVKGTTAGSSWCTGNILYDKVLGSCILGVCYLTKFVQKLLSAGIVFEEEDLNFNN-MGFNTFDNLPGQDVVINSLTESLQILEAYS-------------------DDSLHLTMLKHILKIIICLVHLEDHLT--DYSTKTSHLDELIENANSVNGIFPQLQL------------SPPKGAFSTYIQKHRSNQFPPR--KITKLPTDYSGFITLANDVKTILLVDKAESALETYQFAKFFNKLEQRHVIARILFPLFFIRDDRTVLGKFSYTQFYLLHVKEFSAQTPSEFESSIGN---------ELIQESSNM--LLEWYQNCSQNTCRYRQGFNRQLILWDSLQAQFESVNSQVY------------------------CSWTYFMKLSSMIEFSLKGFDLDIYKPFEAYSMFWYVYYLSHHLETFLKDSQNDIESNINAIHSMNKKLKKLKAGEKKDQLRLKYRFAMDNEMEQLQATKQFLNYLLKEINITKSLCLIEVFQFAILKSFGLIDNKNSTPSKFSNERLIHNLRFKPFNSIGVPELPEYEVFQQTLKDFVIEEKGAAFDIKLERATNFIETEVRNVVSSIDEIMQGIKGGDNNGVLVTGTRLVQELSLEYYCKLKHTSKALSVNSKVIVNTLKKNIKNKDSHEYKVELVHTTEGWNYFPIQTLRIKQDRYK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . **:*. *. * :*: : :* *.***. ::*: :.*:* .: : ..: * . ..: .* * : *:::**:. ::: .:::* * . : * .: .: : . :: : . * ****:: .: : * . :: . . : . ::. :: : . . : . . . : :: : .: :. * .*.. ::.: ** ** . . : : . .* * : . :* :.: . :::* :: * : : . *. :: :: * : . . : : .:. . . : . : . * .* *: : : : : ::* : ::: : :* : : *: : :.**:*::* .* ::** ..* :* .: . :. * . :. * :: : .*: . ** : :: : : : :: . . . ::..*.: :: ** ** :: * * *:: . :: :.:* ::. :::.: . * : : : ::. * :::. :*: * ..::. . .***: .: ", "identical_positions": 78, "similar_positions": 236, "identity": "8.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3062", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LER7-1", "uniprot_id": "A0ABK0LER7_RAT", "id": "A0ABK0LER7-1", "name": "Exportin-4", "aln": "MRRAQSRAGCPATADRANRPASPGAGCRRSHSSAATGITLVSSQLLRTRRSRQAAEGATPTAAATAPEAREAPGSQRRLAGCGACSHNAAHGASLKRDHDGGGAGAPRSDRSAGERGQSSDGEDAGPGEPRDQWDSGWLSRVRPAVRWAPPSMVSNEQRQHAEHIFLSFRKSKSPFAVCRHILETSKVDYVLFQAATAIMEAVVREWVLLEKGSIESLRTFLLTYVLQRPNLQKYVREQILLAVAVIVKRGSLDKSIDCKSIFHEVSQLISSGNPTVQTLACSILTALLSEFSSSSKTSNIGLSMEFHGNCKRVFQEEDLRQIFMLTVGVLQEFSRRENLSAQMSSVFQRYLALANQVLSWNFLPPNLGRHYIAMFESSQNVLLKPTESWREALLDSRVMELFFTVHRKIREDSDMAQDSLQCLAQLASLHGPIFPDEGSQVDYLAHFIEGLLSTINGIEIEDSEAVGISSIISNLITVFPRNVLTAIPSELFSSFVNCLTHLTCSFGRSAALEEVLDKDDMVYMEAYDKLLESWLTLVQDDKHFHKGFFTQHAVQVFNSYIQCHLAAPDGTRNLTANGVASREEEEISELQEDDRDQFSDQLASVGMLGRIAAEHCMPLLTSLLEERVTRLHGQLQRHQQQLLASPGSSTIDNKMLDDLYEDIHWLILVTGYLLADDTQGETPLIPPEIMEYSIKHSSEVDINTTLQILGSPGEKASSIPGYSRTDSVIRLLSAVLRVSEVESRAIRADLTHLLSPQMGKDIVWFLKRWAKTYLLVDEKLYDQISLPLSTAFGADTEGSQWIIGYLLQKVISNLSVWSSEQDLANDTVQLLVTLVERRERANLVIQCENWWNLAKQFASRSPPLNYLSSPVQRTLMKALVLGGFAHMDTETKQQYWTEVLQPLQQRFLRVINQENFQQMCQQEEVKQEITATLEALCGIAEATQIDNVAILFNFLMDFLNNCIGLMEVYKNTPETVNLIIEVFVEVAHKQICYLGESRAMHLYEACLTLLQVYSKNNLGRQRIDVTAEEEQYQDLLLIMELLTNLLSKEFIDFSDTDEVFRGHEPGQAAGRSVSAADVVLYGVNLILPLMSQDLLKFPTLCNQYYKLITFICEIFPEKIPQLPEDLFKSLMYSLELGMTSMSSEVCQLCLEALTPLAEQCAKAQETESPLFLATRHFLKLVFDMLVLQKHNTEMTTAAGEAFYTLVCLHQAEYSELVETLLSSQQDPIIYQRLADAFNKLTASSTPPTLDRKQKMAFLKSLEEFMANVGGLLCVK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ESJ0-1", "uniprot_id": "XPO4_MOUSE", "id": "Q9ESJ0-1", "name": "Exportin-4", "aln": "-----------------------------------------------------------------------------------------------------------------------MMAAALGPPEVIAQLEN------AAKVLMAPPSMVSNEQRQHAEHIFLSFRKSKSPFAVCRHILETSKVDYVLFQAATAIMEAVVREWVLLEKGSIESLRTFLLTYVLQRPNLQKYVREQILLAVAVIVKRGSLDKSIDCKSIFHEVSQLISSGNPTVQTLACSILTALLSEFSSSSKTSNIGLSMEFHGNCKRVFQEEDLRQIFMLTVGVLQEFSRRENLSAQMSSVFQRYLALANQVLSWNFLPPKLGRHYIAMFESSQNVLLKPTESWREALLDSRVMELFFTVHRKIREDSDMAQDSLQCLAQLASLHGPIFPDEGSQVDYLAHFIEGLLNTINGIEIEDSEAVGISSIISNLITVFPRNVLTAIPSELFSSFVNCLTHLTCSFGRSAALEEVLDKDDMVYMEAYDKLLESWLTLVRDDKHFHKGFFTQHAVQVFNSYIQCHLAAPDGTRNLTANGVASREEEEISELQEDDRDQFSDQLASVGMLGRIAAEHCMPLLTSLLEERVTRLHGQLQRHQQQFLASPGSSTIDNKMLDDLYEDIHWLILVTGYLLADDTQGETPLIPPEIMEYSIKHSSEVDINTTLQILGSPGEKASSIPGYSRTDSVIRLLSAVLRVSEVESRAIRADLTHLLSPQMGKDIVWFLKRWAKTYLLVDEKLYDQISLPLSTAFGADTEGSQWIIGYLLQKVISNLSVWSSEQDLANDTVQLLVTLVERRERANLVIQCENWWNLAKQFASRSPPLNFLSSPVQRTLMKALVLGGFAHMDTETKQQYWTEVLQPLQQRFLRVINQENFQQMCQQEEVKQEITATLEALCGIAEATQIDNVAILFNFLMDFLNNCIGLMEVYKNTPETVNLIIEVFVEVAHKQICYLGESKAMHLYEACLTLLQVYSKNNLGRQRIDVTAEEEQYQDLLLIMELLTNLLSKEFIDFSDTDEVFRGHEPGQAAGRSVSAADVVLYGVNLILPLMSQDLLKFPTLCNQYYKLITFICEIFPEKIPQLPEDLFKSLMYSLELGMTSMSSEVCQLCLEALTPLAEQCAKAQETDSPLFLATRHFLKLVFDMLVLQKHNTEMTTAAGEAFYTLVCLHQAEYSELVETLLSSQQDPVIYQRLADAFNKLTASSTPPALDRKQKMAFLKSLEEFMANVGGLLCVK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0E2-1", "uniprot_id": "XPO4_HUMAN", "id": "Q9C0E2-1", "name": "Exportin-4", "aln": "-----------------------------------------------------------------------------------------------------------------------MMAAALGPPEVIAQLEN------AAKVLMAPPSMVNNEQRQHAEHIFLSFRKSKSPFAVCKHILETSKVDYVLFQAATAIMEAVVREWILLEKGSIESLRTFLLTYVLQRPNLQKYVREQILLAVAVIVKRGSLDKSIDCKSIFHEVSQLISSGNPTVQTLACSILTALLSEFSSSSKTSNIGLSMEFHGNCKRVFQEEDLRQIFMLTVEVLQEFSRRENLNAQMSSVFQRYLALANQVLSWNFLPPNLGRHYIAMFESSQNVLLKPTESWRETLLDSRVMELFFTVHRKIREDSDMAQDSLQCLAQLASLHGPIFPDEGSQVDYLAHFIEGLLNTINGIEIEDSEAVGISSIISNLITVFPRNVLTAIPSELFSSFVNCLTHLTCSFGRSAALEEVLDKDDMVYMEAYDKLLESWLTLVQDDKHFHKGFFTQHAVQVFNSYIQCHLAAPDGTRNLTANGVASREEEEISELQEDDRDQFSDQLASVGMLGRIAAEHCIPLLTSLLEERVTRLHGQLQRHQQQLLASPGSSTVDNKMLDDLYEDIHWLILVTGYLLADDTQGETPLIPPEIMEYSIKHSSEVDINTTLQILGSPGEKASSIPGYNRTDSVIRLLSAILRVSEVESRAIRADLTHLLSPQMGKDIVWFLKRWAKTYLLVDEKLYDQISLPFSTAFGADTEGSQWIIGYLLQKVISNLSVWSSEQDLANDTVQLLVTLVERRERANLVIQCENWWNLAKQFASRSPPLNFLSSPVQRTLMKALVLGGFAHMDTETKQQYWTEVLQPLQQRFLRVINQENFQQMCQQEEVKQEITATLEALCGIAEATQIDNVAILFNFLMDFLTNCIGLMEVYKNTPETVNLIIEVFVEVAHKQICYLGESKAMNLYEACLTLLQVYSKNNLGRQRIDVTAEEEQYQDLLLIMELLTNLLSKEFIDFSDTDEVFRGHEPGQAANRSVSAADVVLYGVNLILPLMSQDLLKFPTLCNQYYKLITFICEIFPEKIPQLPEDLFKSLMYSLELGMTSMSSEVCQLCLEALTPLAEQCAKAQETDSPLFLATRHFLKLVFDMLVLQKHNTEMTTAAGEAFYTLVCLHQAEYSELVETLLSSQQDPVIYQRLADAFNKLTASSTPPTLDRKQKMAFLKSLEEFMANVGGLLCVK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q802D3-1", "uniprot_id": "XPO4_DANRE", "id": "Q802D3-1", "name": "Exportin-4", "aln": "------------------------------------------------------------------------------------------------------------------------MMAAVGAPEVISQLES------AAKVLMAPPSMVSTEQRQHAEHIFLSFRKSKSPFAVCKHILETSKVDYVLFQAATAIMEAVVREWILLEKNSIESLRTFLLTYVLQRPNLQKYVREQILLAVAVIVKRGSLDKSINCKSIFLEVSQLISSGNPTVQTLACSILTALLSEFSSSNKTSNIGLSMEFHGSCKRIFQEDDLRQIFMLTMEVLQEFSRRENLNAQMSCVFQRYLALANQVLSWNFLPPNLGRHYIAMFEATPNVMLKPTESWRESLLDHRVMDLFFTVHRKIREDSDMAQDSLQCLAQLASMQGPIFPDESAQVTYLAHLVEGLLNMINGIEIEDSEAVGISNIISNLISTFSRSVLTALPNVLFASFINCLTLLTCSFGRSAALEEVLDKDDMVYMEAYDKLLESWLTLVQEDEHFPRGCFVQPAVQVFNSYIQCHLAAPDGTRNLTANGVASHEEEEINELQEDDRELFSDQLASIGMLGRIAADHCIPLLTGLLEDRVTRLHGQLQRHQQHLMAAADPDTVDRKVLDDLYEDIHWLILVSGYLLADVPQGETPLIPSEVMEYSIKHSTEVDINTTLQLLGSPGEKATSIPGCNRTDSVIRLLSAVLRTSEVESRATRASLTQLLSPQMGKDIVWFLRRWAKTYLLVDEKLYGQISMPLSTAFGADTEGAQWIVGYLLEKVINNLSVWSSEPELANDTVELLVTLVEKRERANIVVQCENWWSLAKQFASRSPPLHMLSSTVQRTLMKALVLGGFAHMDSDTKQQYWAEVLHPLQQRFLNLINQENFAQICQEVAVKQEIVATLEALCGIAEATQIDNVASLFSFLMDFLSSCIGLMEVYRNSPETVNLIIEVFVEVAHKQICYLGETKSMKLYEVCLTLLQVYSKNNLGRKRLDVAAEEDQYQDLLLIMELLTNLLSKEFIDFSDTDEVLRGQEQSSGAGRAVSAADVVLYGVNIVLPLMSQDLLKFPSLCNQYYKLITFICEIFPEKIPQLPEELFKSLMCSLELGMTSMSSEISQLCLEALSPLAEQCAKTQEKDTPLFIATRHFLKLVFDMLVLQKHNTEMTVAAGEALYTLVCLHQAEYSELVETLLSNQRDALIYQRLADAFNNLTASSTPPTMDRKQKVAFLKSLEEFVANVGGLLCVK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. * * :. . * ******..***********************:***************************:****.********************************************:***** *******************************.*************.***:***:*********: ***********.****.********************:**********:: **:*********:*** ***:****************************::*******.:** ****::****. ***************.******:.*.*.****:*. **:**:**** *************************************::*:** :* *.* *****************************:*****.*******: *******:********:**:****.***:**************:::*:....*:*.*:**************:****** .********.*:********:*********:********:**** .***********:**.******* **.**:**************:**************.***:*:**********:***:****:***.******** :******:*******:*****:*:******.************: ***.******************::******:***:*******.:****** *:**: *****.******************* **.******..********:*:************************:::*:***.***************:*:**:***:*****************************:**:* ...*.*:************::************:*************************:****** ************:.*******:********:**.::***:***********************.*****:********************.*:*.:**********:********::*****:*********:**********", "identical_positions": 969, "similar_positions": 144, "identity": "75.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3063", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P01024-1", "uniprot_id": "CO3_HUMAN", "id": "P01024-1", "name": "Complement C3", "aln": "--MGPTSGPSLLLLLLT-------HLPLALG------------SPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDFPGKKLVLSSEKTVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQATFG-TQVVEKVVLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGSGEVVLSRKVLLDGVQNPRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSIN--THPSQKPLSITVRTKKQELSEAEQATRTMQALPYSTVGNSNNYLHLSVLRTELRPGETLNVNFLLRMDR-AHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQP-VPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQPAARRRRSVQLTEKRMDKVGKYPKELRK-CCEDGMRENPMRFSCQRRTRFISLGEACKKVFLDCCN----------------------------------------------------YITELRRQHARASHLGLARSNLDEDIIAEEN-----------------IVSRSEFPESWLWNVEDLKEPPK-NGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQLAFRQPSSAFAAFVKRAPSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKD--ICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVAIAGYALAQMG-RLKGPLLNKFLTTAKDKNRWEDPGKQLYNVEATSYALLALLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLRSEETKENEGFTVTAEGKGQGTLSVVTMYHAK--AKDQLTCNKFDLKVTIKPAPETEKRPQDAKNTMILEICTRYRGDQDATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRDELCRCAEENCFIQKSDDKVTLEERLDKACEPGVDY----------------------VYKTRLVKVQLSNDFDEYIMAIEQTIKSGSDE-VQVGQQRTFISPIKCREALKLEEKKHYLMWGLSSDFWGEKPNLS----YIIGKDTWVEHWPEEDECQDEENQKQCQDLGAFTESMVVFGCPN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AN56-1", "uniprot_id": "A0A8M3AN56_DANRE", "id": "A0A8M3AN56-1", "name": "", "aln": "MLLQLLLWATLLCQICDGKAFPQRHKRTVWGPNMRQIEPVKDPSPSFSLLAPAKIRPGTKQNILVEGHNLAKVVKVTVVVYDYPNSQTALSRGSVSLNSDNNYS--VLQTLEINPNLLLPDGKKKYVKLVAQFSNIYRAEKVMAVSFRSGHIFIQTDKPIYNPGDKVRFRAFVSDLEFRSSERTISLEIQNPDGIAVHG-IGRVKAIDGVFSDIFSLSTVVKEGRWKVVAKFDQGKENVFSREFEVKKYVLPAFNVTLTPKTSHLSLDAEK-LEVEITARYLYGAQVKGVAYVLFGIEINGEKKRL-TSMKQIDDLNG-GSVSLTMEEIKR--AYPDINSLLGSTVYVKASVLTSSGSDLVEAEKSGIKIVNSPYMLTIKDTPKYYKPGLPLAMTVIVSNHDGSPTPNIPVKVTFLKRPISVHSGTINIHINMPKKRIPYGNSQMLKVETVDPSLKPEQQAIQEVYVKPYSTFRSHGNYLHVSVGASRVVVGGSISVQVYIKSSLPNHRALVEHLTYIVLNKGKIIQAG-RVNVKGQDVTSVHLLITSEMLPAFRFVAYYVLP-WQHRAEVVADSVFVDVEDRCVGSLNVGPVDGEIVSSYSPGSSFKFQVKGDVGAKVSLVAVDNAIFLLSK-NRLTQKKVWEVVDQADMGCTAGGGKDNMGVFSDAGLMFHSSTGGSTDSKED--CSSKTKRRRRSAAKLQLRDQLEKAYSDELLQRCCVDGMKEIPMPYSCYRRSLYITEDWSCVLAFLRCCAEYRGEELGVITRPPTTTAPPTTAPPTTSLPTLFDLPYLEYDYMEEKVILRARMIEPMPKLYARANDVGVRQDSYREVVVEEEEEEAASVFEEDDLSDLEDIYVRSKFFESWLWTDIRLPSTAKSDGLAVFPVDTVLPDSITQWGFLAVSASPEKGVCVAEPYNVRVWKPFFIDLRLPHSVSRNEQVEIKAVIHNYK-NSTLEVMVILEKTEDMCSVAYTG-QHRQQVTVAAGSSKLITYTIIPLKTGELPLQVTAVAASFMGQDAVKKNLRVVVEGIQTLKVRSFVLNPSEKGGSAGQQLIQVKKLQLDAVVPKSVPETFVNVRGDLLADSIDNSIKEDSLAALIRMPGGCVEQNLARITLPLIAAHYLDRSADWEIVGISRREEAIKYIQKGYENQLNYKKSDDSYPPYANEGTSTWITAYVVKVFSMAHSFITVNEKHLCGPLLYLLKNKQGYDGTFQEDNPVYDTSMTGAMRGS-EYKASLTAFVLIALAEAQDKVTCQDQEVNIRDKSRQAAGYLTEHFSRLTRPYTAAIACYALAVSNNACVKSMLLKFAS--PDHSHWPDSNNYFFTLEATGYALLALIKSGHMEEAEAPFRWLNEHRGIGGGYGSTQSTMVVLQALSEYLVKRPPPSDLNLLVQLSVPGRSD-VRWTFNPNLAYVARSSRVPLDQEFSVAASGNGKGVLEVVTVYHQLPDVYENSTCNGFQLDVSIAET--NEKTSSDVEKSFRLNVNVRALEERQVRMVILDIGLPTGFEPENSDLELLTNSVDRYINNFQVVDNLSDRGSLIIHLFKVSNKEAEIISFRLNQRFKVGLLQPSTVKVYQYYNKDKSCSRFYSPPEDKQQLDQICEGDVCRCSQGDCCVMKEDSASFGKEQRNAAVCNGLHHGEYFFGSNYSGLLFLSMNNFSSAYRVKLISISQS-HYYQYEMEIVQVIKEGTEEGLNEKERRMFLSHASCRTRLNLREGQEYLVIGPITDVWNAGSTVSNKYVYTLGKETWVERWPDESECG-STLQKKCDELKSFAKKLIEDGCQA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:** : * . * ** :*:::* :* :::.:::*.*: * ***.*:*:*..: .** .. *.. .*: * *: * :: .*::*:*.: * *. .***: **::**::******.**.**..* :* *. : :: . **: ::*:**:**.*: : **:. :.:. :*: *:**: * :::. ::*** *****:****:*:* : *. .. : ** *** ****:*** :*:*.*:*:***: . :: * *:*:* :* *.* *: : : * :.*:*.::**.*:*: ****:*:**:*** **.*** : :..****:***:*: : *:*:* ****: .:** * . *: .* ::.: * :. :.*.* . .*. :** : : . ****. . .****:** :.: * ::.*:. :: . *.* :.: **:::***::::** :*. ***:. : * **::::*:**:****.* . : *******:***:* ***** * . :.* .. **..:.::::** **:* *****:.:*:*.* *:***.*:*:**::**:***.*.*** ******** * **:* .* .: : *.. : *****. : * : *..** : ** ***:* ** :** **: :*: . :* .** ** * : : :***..:*: :.. * :: **: * **:* *****. * ...* :*::. :: .* **** * :**** * :**:***:*::* * : ********:** *******:**::**: *. *:* * * :. :**:* * :*:* **:.. ** :.*.*:***** ::*.*.. .: .*.*:*.*:** ***: *. :. .*: * * * :: :*. **.: .** : ::* :*: ::::. : * ** *.** ***: :* .:**.****.: :** .*:.:*: *:: *:*** :** :::...::..:.:...***:*********:* .:*:::.: ***.: :*: :** **.**** ** . .* *.:*.. * . :*******:* **:* *::* .: .. :*..:* :: .* *.**.*** **** . .:* ** : *:.:* *..: ::.:***.******:: .:: . . .*****:* ********:*::*:***::* . * .:*** *.*.:*.**. : :: : * : **... :: *:*:*.*:*:*.*.***:** . :: *** *:*.*:* : .** ..*.:::: *:: .* :::. * ****.: *** *:..**: *:*.*****.:::: . :***.:***:* ***:.* : ::*:::* *:* *:**.:**** *** ::**:*** * ::. :*:::*..::***:: :* : *.*. :*: : * *:.: .*:.:*:.:. * .: :* * * *.**.*::* :: ::* *:* .** *:*.* :.**: * :*.*. ..:* * :**:****:**:*.** . **:*::* :*::.:: ** ", "identical_positions": 647, "similar_positions": 587, "identity": "36.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3065", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BY89-1", "uniprot_id": "CTL2_MOUSE", "id": "Q8BY89-1", "name": "Choline transporter-like protein 2", "aln": "MGKDSQNYYGKHGTPQKYDPTFKGPIYNRGCTDVICCVLLFLAIVGYVAVGIIAWTHGDPRKVIYPTDSRGEFCGQKGTKNADKPFLFYFNIVKCANPLVLLEFHCPTPQICVKQCPDRYLTLLSARNTR-DFDYYKQFCVPGFQNNKGVTEILRDGECPAVITPSKPLAQRCFPAIHASKG-VLMVGNETTYEDGHGARKNITDLVEGAKKANKILEARQLAMQIFEDYTVSWYWIIIGLVIAMVLSLLFIVLLRFLAGIMVWVMIVMVILVLGYGIFHCYMEYSRLRGEAGSDVSLVDLGFQTDLRVYLHLRQTWMAFMIILSILEVVIILLLIFLRKRILIAIALIKEASRAVGHVMCSLLYPLVTFFLLCLCIAYWASTSVFLSTSNTAVYKVVDDTACPLLRKTCNPETFPLRNESLQCPTARCQFAFYGGESTYHRALLGLQIFNAFMFFWLANFVLALGQVTLAGAFASYYWAMRKPDDMPAFPLFSAFGRALRYHTGSLAFGSLILAIVQIIRVMLEYLDQRLKAAQNKFAKFLMVCLKCCFWCLEKFIKFLNRNAYIMIAIYGTNFCTSARNAFFLLMRNIIRVAVLDKVTDFLFLLGKLLIVGSVGILAFFFFTHRIRIVQDTAPPLNYYWVPILTVIIGSYLIAHGFFSVYGMCVDTLFLCFLEDLERNDGSAERPYFMSSTLKKLLN-------------------------------------------------------------KTNKKVAES------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IWA5-1", "uniprot_id": "CTL2_HUMAN", "id": "Q8IWA5-1", "name": "Choline transporter-like protein 2", "aln": "MGDERPHYYGKHGTPQKYDPTFKGPIYNRGCTDIICCVFLLLAIVGYVAVGIIAWTHGDPRKVIYPTDSRGEFCGQKGTKNENKPYLFYFNIVKCASPLVLLEFQCPTPQICVEKCPDRYLTYLNARSSR-DFEYYKQFCVPGFKNNKGVAEVLQDGDCPAVLIPSKPLARRCFPAIHAYKG-VLMVGNETTYEDGHGSRKNITDLVEGAKKANGVLEARQLAMRIFEDYTVSWYWIIIGLVIAMAMSLLFIILLRFLAGIMVWVMIIMVILVLGYGIFHCYMEYSRLRGEAGSDVSLVDLGFQTDFRVYLHLRQTWLAFMIILSILEVIIILLLIFLRKRILIAIALIKEASRAVGYVMCSLLYPLVTFFLLCLCIAYWASTAVFLSTSNEAVYKIFDDSPCPFTAKTCNPETFPSSNESRQCPNARCQFAFYGGESGYHRALLGLQIFNAFMFFWLANFVLALGQVTLAGAFASYYWALRKPDDLPAFPLFSAFGRALRYHTGSLAFGALILAIVQIIRVILEYLDQRLKAAENKFAKCLMTCLKCCFWCLEKFIKFLNRNAYIMIAIYGTNFCTSARNAFFLLMRNIIRVAVLDKVTDFLFLLGKLLIVGSVGILAFFFFTHRIRIVQDTAPPLNYYWVPILTVIVGSYLIAHGFFSVYGMCVDTLFLCFLEDLERNDGSAERPYFMSSTLKKLLN-------------------------------------------------------------KTNKKAAES------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BD93-1", "uniprot_id": "A0A8M2BD93_DANRE", "id": "A0A8M2BD93-1", "name": "Choline transporter-like protein 2", "aln": "MEPEEKNPESKYGEPRKFDPTFKGPIYNRGCTDILCCILFILALLGYFAVGILAWSQGDPRKVIYPTDSTGQFCGQAGTPLEKKPLLFYFNIMKCASPLVLLEFQCPTTQICVEKCPDKFMTLVNALKSQSDKTYYTQFCKEGVDMTKNAPQILSEGLCPSILFPSKNFTRRCLPALETMKGGVVVIGNETQFTVDQGEVINATDLLNAAKKSNVVVEARAVAMRIFEDYTQSWHWILLGLVIAMLISLIFILLLRFLAGVMVWVMIIMVIIVIGYGIFHCYMQYASLKGQAGSDVTIKDLGLQTDFSVYLQIQQTWLAFMIILCIVEAVILLLLIFLRKRLLIAIALIKEASKAIGHVMSSLFYPLLTYALMSLVIAYWAITAVFLSTSNEPIYKVFNTSNCSYSRATCNPATFNTSNVTTECPDAECLFAFYGGETLYHKWLIVFQFYNLFLFFWCVNFVIALGQVTLAGAFASYYWAFKKPDDMPAFPIFNSLGRALRYHTGTLAFGSLILAIVQVIRVVLEYLDQKLKGAQNKFAKFLLSCLKCCFWCLEKFIKFINRNAYIMVAIYGKNFCTSARDAFFLLMRNIVRVAVLDKVTDFLLFLGKLLIVGIVGICSFFFFTGKIKIAQDVTPALNYYWVPILTVVFGAYLIAHGFFSVYAMCVDTLFLCFCEDLERNDGSSDKPFFMSPELHQILSIEKSIEETDHAEVPVIQVQAEEEIPLQENGEVQLKQQTVLKQDQEEETPLNQETHIEEAPQETQTQAPEASAVAEEKPEEQVTAQEHEPTQATPQQNGPQEVDAEDKEEPGAQAEPPQAENLQAPEPEEPKPQENGPQESDTLLTPQE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : .*:* *:*:***************::**::::**::**.****:**::************ *:**** ** .** ******:***.*******:***.****::***:::* :.* .:: * **.*** *.. .*...::* :* **::: *** :::**:**:.: ** *:::**** : .:* * ***::.***:* ::*** :**:****** **:**::****** :**:**:*******:******:***:*:*********:*: *:*:*****:: ***:***: ***:::***:******.*:*.:*:*********:***********:*:*:**.**:***:*: *:.* ***** *:******* .:**:.: : *. **** ** * : :** *.* *******: **: *: :*::* *:*** .***:*****************::****:****:*.::*********:****:*******:***:******:**.*:***** *: ***************:*******:****.*******:*********:************::******** *** :***** :*:*.**.:*.***********:.*:***********.********** *********:::*:***. *:::*. :*:.:..*: ", "identical_positions": 463, "similar_positions": 174, "identity": "54.66%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-309", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CHH9-1", "uniprot_id": "SEPT8_MOUSE", "id": "Q8CHH9-1", "name": "Septin-8", "aln": "---MAATDLERVSNAEPEPRSLSLGGHVGFDSLPDQLVSKS--------------------VTQGFSFNILCVGETGIGKSTLMNTLFNTTFET---------EEASHHEECVRLRPQTYDLQESNVHLKLTIVDAVGFGDQINKDDSYRPIVDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVA----EINAVMNAHLPFAVVGSTEEVKVGNKL--VRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSDGDSQPFSLQ----------------ETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRIHQEEKR----------------------KVEEKRRELEEETNAFNCRKAAMEALQSQALHATSQQPLRKDKDKKN------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0BNF1-1", "uniprot_id": "SEPT8_RAT", "id": "B0BNF1-1", "name": "Septin-8", "aln": "---MAATDLERISNAEPEPRSLSLGGHVGFDSLPDQLVSKS--------------------VTQGFSFNILCVGETGIGKSTLMNTFFNTTFET---------EEASHHEECVRLRPQTYDLQESNVHLKLTIVDAVGFGDQINKDDSYRPIVDYIDTQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVA----EINAVMNAHLPFAVVGSTEEVKVGNKL--VRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSDGDSQPFSLQ----------------ETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRIHQEEKR----------------------KVEEKRRELEEETNAFNCRKAAMEALQSQALHATSQQPLRKDKDKKK---VGGWSSIYSVTIP--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92599-1", "uniprot_id": "SEPT8_HUMAN", "id": "Q92599-1", "name": "Septin-8", "aln": "---MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKS--------------------VTQGFSFNILCVGETGIGKSTLMNTLFNTTFET---------EEASHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVA----EINAVMNAHLPFAVVGSTEEVKVGNKL--VRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSDGDSQPFSLQ----------------ETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRVHQEEKR----------------------KVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQPLRKDKDKKNRSDIGAHQPGMSLSSSKVMMTKASVEPLNCSSWWPAIQCCSCLVRDATWREGFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q642H3-1", "uniprot_id": "SEP8A_DANRE", "id": "Q642H3-1", "name": "Septin-8-A", "aln": "---MAATDVDIFSNEE--KRNLSLGGHVGFDSLPDQLVSKS--------------------VTQGFCFNILCVGETGIGKSTLMNTLFNTMFEN---------EEASHYQNGVYLRPRTYDLQESNVHLKLTIVDTVGFGDQINKEESYKPIVDYIDTQFENYLQEELKVKRSLFNYHDTRIHICLYFISPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMSELVSNGVQIYQFPTDDEAVT----EINSSMNAHLPFAVVGSVEEVKVGNKT--VRARQYPWGVVQVENESHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKLEEMGFKDTDPDSQPFSLQ----------------ETYEAKRKEFLGDLQKKEEEMRQMFVNKVKETEAELKEKERELHEKFEQLKRMHQEEKR----------------------KVEEKRRELEEEMNAFNRRKVAAETLS-------LSQPLKKDKDKKN------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P54359-1", "uniprot_id": "SEPT2_DROME", "id": "P54359-1", "name": "Septin-2", "aln": "----MSVEVDFVDKKEVHLRTLKQSGHVGFDSLPDQLVNKS--------------------VQNGFVFNVMCIGETGLGKSTLMDTLFNTSFES---------TPSPHTLPSVKLKAHTYELQESNVRLKLTICDTVGYGDQINKDDSFKAVVDYIDAQFENYLQEELKIKRSLVTCHDSRIHICLYFICPTGHGLKSLDLVCMKKLDSKVNIIPVIAKADTISKVELQRFKAKIIQELNANGVHIYQFPTDDETVA----ETNTSMNSHIPFAVVGSTEFIKVGNKL--IRARQYPWGTVQVENETHCDFVKLREMLIRTNMEDMREKTHTRHYELYRQKRLEQMGFSDVDSDNKPISFQ----------------QTFEAKRSNHLAELQSKEEEVRQMFVQRVKEKEAELKESEKDLHAKFEKLKRDHAEEKR----------------------KLEESRKALEEDYLDFQRRKQQLATAH---------HTLTLGKSKKK------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32458-1", "uniprot_id": "CDC11_YEAST", "id": "P32458-1", "name": "Cell division control protein 11", "aln": "-MSGIIDASSALRKRKHLKRGITFTVMIVGQSGSGRSTFIN----------------------------TLCGQQVVDTSTTILLP-----------------TDTSTEIDLQLREETVELEDDEGVKIQLNIIDTPGFGDSLDNSPSFEIISDYIRHQYDEILLEESRVRRNPR-FKDGRVHCCLYLINPTGHGLKEIDVEFIRQLGSLVNIIPVISKSDSLTRDELKLNKKLIMEDIDRWNLPIYNFPFDEDEISDEDYETNMYLRTLLPFAIIGSNEVYEMGGDVGTIRGRKYPWGILDVEDSSISDFVILRNALLISHLHDLKNYTHEILYERYRTEALSGESVAAESIRPNLTKLN---------------GSSSSSTTTRRNTNPFKQSNNINNDVLNPASDMHGQSTGENNETYMTREEQIRLEE--------------------------ERLKAFEERVQQELLLKRQELLQREKELREIEARLEKEAKIKQEE--------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q07657-1", "uniprot_id": "SHS1_YEAST", "id": "Q07657-1", "name": "Seventh homolog of septin 1", "aln": "MSTASTPPINLFRRKKEHKRGITYTMLLCGPAGTGKTAFANNLLETKIFPHKYQYGKSNASISSNPEVKVIAPTKVVSFNSKNGIPSYVSEFDPMRANLEPGITITSTSLELGGNKDQGKPEMNEDDTVFFNLIMTHGIGENLDDSLCSEEVMSYLEQQFDIVLAEETRIKRNPR-FEDTRVHVALYFIEPTGHGLREVDVELMKSISKYTNVLPIITRADSFTKEELTQFRKNIMFDVERYNVPIYKFEVDPEDDDLESMEENQALASLQPFAIITSDTRDSEGRYV-----REYPWGIISIDDDKISDLKVLKNVLFGSHLQEFKDTTQNLLYENYRSEKLSS-VANAEEIGPNSTKRQSNAPSLSNFASLISTGQFNSSQTLANNLRADTPRNQVSGNFKENEYEDNGEHDSAENEQEMSPVRQLGREIKQENENLIRSIKTESSPKFLNSPDLPERTKLRNISETVPYVLRHERILARQQKLEELEAQSAKELQKRIQELERKAHELKLREKLINQNKLNGSSSSINSLQQSTRSQIKKNDTYTDLASIASGRD-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : * :. : : ..: . . :. :. .:. . :. . :.. : :.: : * *:.::.. . . : .*: *:: * ** :::*. .* *:* .**:* ****.*:.:*: ::.:.. .*::*:*:::*:::: ** : *: :: .: **:* * : * * : : ***:: * . * *:**** :.:::.. .*: *:: *: ::.:::: *: ** ** *. . : . : . .: ::: . : : . : :.: . . . : : . :. .. : .: ", "identical_positions": 53, "similar_positions": 141, "identity": "9.48%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3097", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G3P6-1", "uniprot_id": "A0A8I6G3P6_RAT", "id": "A0A8I6G3P6-1", "name": "Helicase ARIP4", "aln": "-------------------------------------MSDESASGS--DPDLDPD------------EEEVAVEEHDRDDEEGLLDDPSLEG------------MCG-TEHAQLGEDGQRPPRCTSTTSSQSEPSEQLR-HQGKILASEDPKKK-------------------------------------RAQKPSHMRRNIRKLLREDQLEPVTKAAQQEELERRKRLEQQRKEYAAPIPTVPLEFLPEEIVLRASDGPQ----------LPPRVLAQEVICLDSSSGSEDEKSS---------------RDEVIELSSGEE-DTLHIVDSSE-SVSEEDEEEE---KGGTHVNDALNQHDALGRVLVNLNHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVISFIDVLFRHTPAKTVLAIVPVNTLQNWLAEFNMWLPAPEALPADSKPEEIQPRFFKVHILNDEHKTVASRAKVTTDWVSEGGVLLMGYEMYRLLTLKKSLATGRPKKTKKRSHPVIIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSQIQRDLYTQFMDRFRDCGSSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKEN------------------------------------------------------------------------------------------------------------------------------------LANEQDLDVEELGSAGTSTRCPPHGTKVKGEDSALPSSMGEATNSKFLQGVGFNP------FQERGNNIVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFLGKRDMPCPPGAEGQGAQKWVRNVSYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKIYDRQISKQGMSDRVVDDLNPMLNFTRKEVENLLHFVEKEPAPQTSLDIKG---------IKESVLQLACLKYPHLITKEPFEHESLLLNRKDHKLTKAEKKAAKKSYEEDKRTSVPYTR----------------PSYAQYYPASDQSLTSIPAFSQRNWQPTLKGDDKPVASVRPVQS------------TPIPMMPRHVPLGGSVSSASNTNPSMNFPINYLQRAGVLVQKVVTTTDIVIPGLNSSTDVQARISAGESIHIIRGTKGTYIRTSDGRIFAVRATGKPKAPEDGRMAASGSQGPSLASTSNGRHSASSPKAPDPEGLARPVSPDSPEIISELQQYADVAAARESHQNSPSISAALPGPPAQLMDNSTIPGTALGTEPCLGGHCLNSSLLVTGQPSSGRHPVLDLRGHKRKLATPSVSQESVRRRSRKGHLPAPVQPYEHGYPVSGGFSMPPVSLNHNLTTPFTSQAGENSLFMGSNPSYYQLS-NLLADARLVFPVTTDPLVPAGPVSSSSTATSVTASNPSFMLN---PSVPGILPSYSLPFSQPLLSEPRMF-------APFPSPVLPSNLS-RGMSVYPGYMSPHAGYPAGG-LLRSQVPPFDSHEVAEVGFSSNDDEDKDDDVIEVTGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99NG0-1", "uniprot_id": "ARIP4_MOUSE", "id": "Q99NG0-1", "name": "Helicase ARIP4", "aln": "-------------------------------------MSDESASGS--DPDLDPDVELEDEEEEEEEEEEVAVEEHDRDDEEGLLDDTSLEG------------MCG-TEHAQLGEDGQRPPRCTSTTSSQSEPSEQLR-HQGKILASEDPKKK-------------------------------------RAQKPSHMRRNIRKLLREDQLEPVTKAAQQEELERRKRLEQQRKEYAAPIPTVPLEFLPEEIVLRASDGPQ----------LPPRVLAQEVICLDSSSGSEDEKSS---------------RDEVIELSSGEE-DTLHIVDSSE-SVSEEDEEEE---KGGTHVNDALNQHDALGRVLVNLNHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVISFIDVLFRHTPAKTVLAIVPVNTLQNWLAEFNMWLPAPEALPADSKPEEVQPRFFKVHILNDEHKTVASRAKVTADWVSEGGVLLMGYEMYRLLTLKKSLATSRPKKTKKRSHPVIIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSQIQRDLYTQFMDRFRDCGTSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKEN------------------------------------------------------------------------------------------------------------------------------------LANEQDLDVEELGSAGTSARCPPHGTKVKGEDSALPSSMGEATNSKFLQGVGFNP------FQERGNNIVTYEWAKELLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFLGKRDMPCLPGAEGQGTQKWVRNVSYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCHIYRLVADYTLEKKIYDRQISKQGMSDRVVDDLNPMLNFTRKEVENLLHFVEKEPAPQTSLDIKG---------IKESVLQLACLKYPHLITKEPFEHESLLLNRKDHKLTKAEKKAAKKSYEEDKRTSVPYTR----------------PSYAQYYPASDQSLTSIPAFSQRNWQPTLKGDEKPVASVRPVQS------------TPIPMMPRHVPLSGGVSSASSTNTSMNFPINYLQRAGVLVQKVVTTTDIVIPGLNSSTDVQARINAGESIHIIRGTKGTYIRTSDGRIFAVRATGKPKAPEDGRMAASGSQGPSLASTSNGRHSASSPKAPDPEGLARPVSPDSPEIISELQQYADVAAARESRQSSPSVSAALPGPPGQLMDNSTIPGTALGTEPCLGGHCLNSSLLVTGQPSGGRHPVLDLRGHKRKLATPSVTQESVRRRSRKGHLPAPVQPYEHGYPVSGGFAMPPVSLNHNLTTPFTSQAGENSLFMGSNPSYYQLS-NLLADARLVFPVTTDPLVPAGPVSSSSTATSVTASNPSFMLN---PSVPGMLPSYSLPFSQPLLSEPRMF-------APFPSPGLPSNLS-RGVSVYPGYMSPHAGYPAGG-LLRSQVPPFDSHEVAEVGFSSNDDEDKDDDVIEVTGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y4B4-1", "uniprot_id": "ARIP4_HUMAN", "id": "Q9Y4B4-1", "name": "Helicase ARIP4", "aln": "-------------------------------------MSDESASGS--DPDLDPDVELEDAEEEEE-EEEVAVEECDRDDEEDLLDDPSLEG------------MCG-TEHAQLGEDGQQPPRCTSTTSSQSEPSEQLRRHQGKNLASEDPKKK-------------------------------------RAQKPSHMRRNIRKLLREDQLEPVTKAAQQEELERRKRLEQQRKDYAAPIPTVPLEFLPEEIALRASDGPQ----------LPPRVLAQEVICLDSSSGSEDEKSS---------------RDEVIELSSGEE-DTLHIVDSSE-SVSEDDEEEE---KGGTHVNDVLNQRDALGRVLVNLNHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVISFIDVLFRHTPAKTVLAIVPVNTLQNWLAEFNMWLPPPEALPADNKPEEVQPRFFKVHILNDEHKTMASRAKVMADWVSEGGVLLMGYEMYRLLTLKKSFATGRPKKTKKRSHPVIIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSKIQRDLYTQFMDRFRDCGSSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKES------------------------------------------------------------------------------------------------------------------------------------LANEQDLDVEELGSAGTSARCPPQGTKGKGEDSTLASSMGEATNSKFLQGVGFNP------FQERGNNIVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFLGKREVPCPPGTEGQGAQKWVRNISYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKIYDRQISKQGMSDRVVDDLNPMLNFTRKEVENLLHFVEKEPAPQVSLNVKG---------IKESVLQLACLKYPHLITKEPFEHESLLLNRKDHKLTKAEKKAAKKSYEEDKRTSVPYTR----------------PSYAQYYPASDQSLTSIPAFSQRNWQPTLKGDEKPVASVRPVQS------------TPIPMMPRHVPLGGSVSSASSTNPSMNFPINYLQRAGVLVQKVVTTTDIVIPGLNSSTDVQARINAGESIHIIRGTKGTYIRTSDGRIFAVRATGKPKVPEDGRMAASGSQGPSCESTSNGRHSASSPKAPDPEGLARPVSPDSPEIISELQQYADVAAARESRQSSPSTNAALPGPPAQLMDSSAVPGTALGTEPRLGGHCLNSSLLVTGQPCGDRHPVLDLRGHKRKLATPPAAQESSRRRSRKGHLPAPVQPYEHGYPVSGGFAMPPVSLNHNLTTPFTSQAGENSLFMGSTPSYYQLS-NLLADARLVFPVTTDPLVPAGPVSSSSTATSVTASNPSFMLN---PSVPGILPSYSLPFSQPLLSEPRMF-------APFPSPVLPSNLS-RGMSIYPGYMSPHAGYPAGG-LLRSQVPPFDSHEVAEVGFSSNDDEDKDDDVIEVTGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BLB3-1", "uniprot_id": "A0A8M2BLB3_DANRE", "id": "A0A8M2BLB3-1", "name": "", "aln": "-------------------MRSEWRCVSNALGDPGDAMSEEAISGSDLEPSLNSEEEEEEEEMDEEEEEDGENDGDDEEDAGDQLESLEMEDRRDPSSPAPTSPMSGDSSPERLSRPASRPSSTSRTSSRPGSQPPSSPDTRSNASANSNTKKKT-----------------------------------SKTSKPAHLRRNIRKLLTENQLEAGTKAAQQEELERRRRLEQQRKEFS----------LHADLATAAAGS------------------KQEVICLDSSGDEGEEKEAP-------PPPLPDHRDDVIELSSGDEGDALRISSEEEEDRSLTPGTEE---SSGSHINDSLNQPDSQGRVLININHPAEEEDLFLAPQLARAVKPHQIGGIRFLYDNLVESLERYKTSSGFGCILAHSMGLGKTLQVISFIDVLLRHTGAKTVLAIVPVNTLQNWLAEFNLWLPAAEALPPDTDPQQVLPRTFKVHILNDEHKTTVARAKVVEDWTGDGGVLLMGYEMYRLLSLKKSFVTGRKRKSKKPAGPVIIDLDEEDRQQELMKAIERALSRPGPDVVICDEGHRIKNCHASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVQLMRYRSHVLHSLLEGFVQRRGHDVLRHQLPPKEEHVILVRLSRLQRALYTEFMNRFREAGNSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKEN------------------------------------------------------------------------------------------------------------------------------------LANEQDLDLDDLNSS-SGTRCSAPGIKSKTSD---------AANSRQMSVGHLNP------LQEKANQVITYEWAKEVMTNYQTGVLENSAKMVLLFYLIDETVARGDKILVFSQSLSTLTVIEDFLSRRPMPIQTET---GTHNWVRNINYYRLDGSTSASERERLINQFNDPANTQAWVFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQRKPCHIYRLVCDFTLEKKIYDRQVSKQGMSDRVVDDLNPVLNFTRKEVESLLHFVEEEPDP-AELQPNN---------EMETVIQQACVMYPHLLTKPPFHHESLLMDRKEMKLTKAEKRAAKKSYEDEKRASVPYQR----------------PSYAHYYPASDQRLTNIPAFSQRNWRPPPHLEEKPVASVRPVQS------------TPIPMMPRQVPMG--VPSSSTG-----FPVNYLQKAGVYVQRVVTTTDIVIPGSNSSTDVQARIGAGESIHVIRGSKGTYIRTNDGRIFAIRS-GKPRPPEGGATASREDCGPPLHSVSNGRASPQEPKRLTPEALPRPSSRESPRFHREFHSNKEAVASAENLTSSG--TPESTGADRPIQHPSHLPEQHR-------------------QLSNDIASSVDVQSLKRKLLESRTSKQPGGKRTSTSTSAAGSYP---GFPLNSGFGFPSMALNPALLGALGHVTPPS---LGSRSHLMQQAGQTLGDLHAMFPTEPLGLGVSNSTLSSTCSTNTTSSSHSGMLASSSSSVPSSSLSSTSSSLPPFMMNPSMASMLSGFPVPFSQPLFPGSLHPRGLSSTSTPASTASSFLSSSSLLGTAFSRPDTHP----SLTENGGSSSDDDVIEVMGQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1A8-1", "uniprot_id": "Q9W1A8_DROME", "id": "Q9W1A8-1", "name": "Helicase ARIP4", "aln": "MDNPEANMEESNPNYDVNQRLQKPEGWPHVNEFHPSMMYPDDPRRYFHNASTDPQHQPQQHPQQQPEQHPEQHPQHPLHSQQQPQQHPQQQPQQHPQQQTQQPPQLQPQQHPQAQIQPPIPVPISTPMEGTMEVPVKMPEYCPETSQPVEPDRVINPLAEVAKNTVPYGHKRKNSAGEDQAANKKLSMAAAEEKKNSHLRKNIRDVMNENNLDTTTLAAQREESERLARVAGQQKSMREIQKQVVHKQIFRILQLDESEGIESCAVANPVEHHPPVDFPEEEIASDTFDDSNSSSLSGGSIEDVLHKGASVQPSEVVTIDDSSDDDCILLSEEEEEEDDEDLNESDDATNSGMHVKDIYNVPDENGQVVVNMAHPEGEETLYLAPQIAKVIKPHQIGGVRFLYDNIIESTRRYNKSSGFGCILAHSMGLGKTLQVVSFCDIFLRHTSAKTVLCVMPINTLQNWLSEFNMWIPR------YSTDSNVRPRNFDIFVLNDQQKTLTARAKVILNWVHDGGVLLIGYELFRLLALKLVKTRKRKGS--------VIRPDGMDSSSDLMNLVYEALVKPGPDLVICDEGHRIKNSHAGISLALKEIRTRRRIVLTGYPLQNNLLEYWCMVDFVRPNYLGTRTEFCNMFERPIQNGQCVDSTPDDIKLMRYRAHVLHSLLLGFVQRRSHTVLQLTLPQKYEYVILVKMTAFQRKLYDTFMTDVVRTK----AFPNPLKAFAVCCKIWNHPDVLYNFLKKCETDLDLEIDEEVTKGAATPIVEPSADSSLSLASPLEKKINGSGDPINSIETFSKAENQTLFNIPASSDLNAKYLNKSPSFYDEKPEPLNYGSFGSEGKNNYWMDSSILPKPGCVEVIKQTDTNMSSNFESITGSSEIVDLDTNEIKTVETTIQAPCSNNQLDNGCNAGKPSEWNAAGSKNSSGVAAAEPFKKLLKSKQRNEEFSCSWAVDLMKNYVSGLISNSPKMEIFFCILKESLNLGDRILLFSQSLLTLNLLEVYLKSSYVPG-------SNQLWTKNSSYFRLDGSTSSQERERLVNEFN--ANSNVKLFLISTRAGSLGINLTGANRVIIFDASWNPCHDTQAVYRIYRYGQTKPCFVYRIVMDRCLEKKIYDRQIKKQGMSDRIVDECNPEAHLSMKDITNLCQDYDSDEDTVEEVNKSTGDLSKPGSPSEEGSKPGSANMSPNASNKSNNGPTKPLDDQNTPKSPNGASHSPIKTEKNDGQEHAVHVDGIINTILDMHRHCVTKEPFMHESLLVDQKDRKLSQAEKRQAHRSYELEKKAAVNQRFTYAPAKMNYKIVNNDGTVITKPMNQQIKTNTSSSTGGRSTRWIPADVWQRQGMTAQEMTLPLDVVIP-TNSADKANIILKAGQRVMVLKSAKGIYMQLDSGKIIAIRTTAKTEP-------EKTNKDDVIDITDDGDTDTTKPQSPE-EDVKDLTADDEPRVVKNKESNPATTSRPEMPAKDRKSTENVQHFKSQTQPNTTLATTTN------------------------QHQLPSDLTYSQPQQSHQQPQQQASQQQPAQQPPPPAYKHQNHLPAAGEGYSNANSIQPNVPLPPHPGAPNSSEAPPPADSSYFQPKPFQHTYPPQYYDYYDNKHKSAPPGSGYHINNYTSYGNLNFAP----------YHSNLHPPASYIGAPSSY---------VNSNVFPRQHWSSVVNSSPASSESMRQPSYIG---------------------------STYPVNEWSSQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : :.. :.: :. .. : . : . : * : . . . . . : :..: . .* :*:*:***.:: *::*:. * ***:** ** *: *:*. : : : . :* *. *: ... ... : .:*: :....: * : : ...* . . .: ..* *::* * * *:*::*: ** ** ::****:*:.:*******:******::** .*::.********************:** *:::*** *****.::*:*******:***:*:* . .:: ** *.:.:***::** .:**** :*. :*****:***::***:** . * . :* * * ..:: . . .** :****:***********.:*. * ***:**:***:***********:***********::**** **.******* ****:****:*::*****:******* ******.* **: ** * * ****::: :** ** ** . ******.*************: *:* . :: *** ::: : : :.. . : . *:.*: . .:: *: .: .** :::.** :*::.**.** ::* ::.*:: **:**:***** ** ::* :* :* . : *.:* .*:******.: *****:*:** :* . :**:*****.**:** *****::**********:*** *:***** ***.:**:* * *********:.*******:**: ** ::: *:: .* : :.: . .:: . * :. *: .* . * ::: * .:. .::. *: ::: : . : .: : ** .:. .:*: : . . :.*.... * . : .: * : : ..*:: :* : *: *: .*.:. . *:*** **: ..: : **: : :::.:** *:: ..*:*:*:*: .*.. . . ..:* .. .*: * : : :.*.. : .. ..: * .. . : :. . .: .:: :: .. * . . ::: : . : . . . : : . *. .. *: . : . . : * . . :* . :. . .. . . * * .:", "identical_positions": 419, "similar_positions": 408, "identity": "23.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3102", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P14901-1", "uniprot_id": "HMOX1_MOUSE", "id": "P14901-1", "name": "Heme oxygenase 1", "aln": "--MERPQ---PDSMPQDLSEALKEATKEVHIQAENAEFMKNFQKGQVSREGFKLVMASLYHIYTALEEEIERNKQNPVYAPL---------YFPEELHRRAALEQDMAFWYG---------PHWQEIIPCTPATQHYVKRLHEVGRTHPELLVAHAYTRYLGDLSGGQVLKK---IAQKAMALPSSGEGLAFFTFPNIDSPTKFKQLYRAR-MNTLEMTPEVKHRVTEEAKTAFLLNIELFEELQVMLTEEHKDQSPSQMASLRQRPASLVQDTAPAETPRGKPQISTSSSQTPLLQWVLTLSFLLATVAVGIYAM-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06762-1", "uniprot_id": "HMOX1_RAT", "id": "P06762-1", "name": "Heme oxygenase 1", "aln": "--MERPQ---LDSMSQDLSEALKEATKEVHIRAENSEFMRNFQKGQVSREGFKLVMASLYHIYTALEEEIERNKQNPVYAPL---------YFPEELHRRAALEQDMAFWYG---------PHWQEAIPYTPATQHYVKRLHEVGGTHPELLVAHAYTRYLGDLSGGQVLKK---IAQKAMALPSSGEGLAFFTFPSIDNPTKFKQLYRAR-MNTLEMTPEVKHRVTEEAKTAFLLNIELFEELQALLTEEHKDQSPSQTEFLRQRPASLVQDTTSAETPRGKSQISTSSSQTPLLRWVLTLSFLLATVAVGIYAM-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09601-1", "uniprot_id": "HMOX1_HUMAN", "id": "P09601-1", "name": "Heme oxygenase 1", "aln": "--MERPQ---PDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKESPVFAPV---------YFPEELHRKAALEQDLAFWYG---------PRWQEVIPYTPAMQRYVKRLHEVGRTEPELLVAHAYTRYLGDLSGGQVLKK---IAQKALDLPSSGEGLAFFTFPNIASATKFKQLYRSR-MNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTHDTKDQSPSRAPGLRQRASNKVQDSAPVETPRGKPPLNTR-SQAPLLRWVLTLSFLVATVAVGLYAM-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0UXS0-1", "uniprot_id": "B0UXS0_DANRE", "id": "B0UXS0-1", "name": "Heme oxygenase", "aln": "--MDSTKSKAAENTGSDLSEQIKAVTKDSHVRAENTQLMLSYQKGQITQTQYKLLLCSLYEIYRALEEELDRNADHPAVQPI---------YFPQELARLEALGQDLEHFFG---------PQWRKRITVPAATHRYAQRLREIGKSSPELLVAHAYTRYLGDLSGGQVLGK---ITQKSLGLTGN-KGILFFSFPGVTSANRFKQLYRSR-MNSIEFTEQKRQEALDEAVRAFEFNIDVFDDLQKMLSITEEASSDKGNEAASQS-------------------LSKTFSSSPALQFALGVGITLATVGMGVYAF-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGJ9-1", "uniprot_id": "Q9VGJ9_DROME", "id": "Q9VGJ9-1", "name": "Heme oxygenase", "aln": "--MSASEETIADSQVSENVEDVEFVDMAFTKELRKATKDVHNLTDVLVNAKIALALSDDEVWYDGLLAFYELYKFFETHLPER--------LLPKEFHRTAAFERDFAYFYG---------SDWRKDYEIRPAVQKYLEHLEKIAAQNELLLFAYSYQMYMALMSGGQMLQKKRMIARKMWIFSKNDDEEQQKQADKEAELATARAADGSVDKDDLEARPMPAQVTICPPGCEATYFPEKISVLKAKLRRVFNNHYGAFDDDLRAAFIEESRNVFRLNIEVVR--TIKGVNRANLRKLALALIFVSSIVVAVKFALK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32339-1", "uniprot_id": "HMX1_YEAST", "id": "P32339-1", "name": "Heme-binding protein HMX1", "aln": "MEDSSNTIIPSPTDVGALANRINFQTRDAHNKIN-TFMGIKMAIAMRHGFIYRQGILAYYYVFDAIEQEIDRLLNDPVTEEELQTSTILKQFWLEDFRRSTQIYKDLKLLYSNTFKSTESLNEFLATFQKPPLLQQFINNIHENIHKEPCTILSYCHVLYLALFAGGKLIRS---NLYRRLGLFPNFEKLSQKELVKKGTNFFTFSDLGPTEETRLKWEYKKNYELATRTELTEAQKLQIISVAEGIFDWNFNIVAEIGELNRRELMGKFSFKCITYLYEEWMFNKDSATRRALHTVMLLVLSIIAIWVLYFLVKSFLSIV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : :: . . : : : .: : . ::: * : :*: :. : . ::: :.:.: :.::.: *:. ::**::: . : : . . . :: . : :. : : : . : * : : * ", "identical_positions": 7, "similar_positions": 64, "identity": "2.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3112", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ULX3-1", "uniprot_id": "NOB1_HUMAN", "id": "Q9ULX3-1", "name": "RNA-binding protein NOB1", "aln": "--MAPVEHVVADAGAFLRHAALQDIGKNIYTIREVVTEIRDKATRRRLAVLPYELRFKEPLPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKQEPQK-VKVSSSIQHPETPLHISGFHLPYKP--KPPQE-TEKGHSACEPENLEFSSFMFWRNPLPNIDHELQELLID----------------------RGEDVPSEEEEEEENGFEDRKDDSDD-DGGGWITPSNIKQIQQELEQCDVPEDVRVGCLTTDFAMQNVLLQMGLHVLAVNGMLIREARSYILRCHGCFKTTSDMSRVFCSHCGNKTLKKVSVTVSDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAINPHLTEDQRFPQLRLSQKARQKTNVFAPDYIAGVSPFVENDISSRSATLQVRDSTLGAGRRRLNPNASRKKFVKKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BW10-1", "uniprot_id": "NOB1_MOUSE", "id": "Q8BW10-1", "name": "RNA-binding protein NOB1", "aln": "--MAPVEHVVADAGAFLRDAPLQDIGKNIYTIREVVREIRDKATRRRLAVLPYQLRFKEPLPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKKEPEK-AKVSSSIQHPETALHISGFHLPSKS--KPLQEAVDRGHAADGPENLEFSSFMFWRTPLPNIDRELQELLID----------------------GRE----EEEEEEE------CEDSDD-DGGGWITPSNIKQIQQELEQCDTPEDVQVGCVTTDFAMQNVLLQMGLHVLAVNGMLVREARSYILRCHGCFKTTSDMNRVFCGHCGNKTLKKVSVTINDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAINPHLTEDQRFPQLRLSQKARQKTDVFAPDYIAGVSPFAENDISSRSAILQVRDGMLGAGRRRLNPNASRKKFVKKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "I3ISV3-1", "uniprot_id": "I3ISV3_DANRE", "id": "I3ISV3-1", "name": "RNA-binding protein NOB1", "aln": "MVATIVEHVVVDAGAFIKRAPLHEIGKNIYTLKDVVDEIRDKPTKRSLAFLPYKLDFKEPFPEYIQFVTEFAKKTGDYPSLSATDIKVLALTYQLESENVGTEHLKKEPEKQVQICSTQRHPETPVGIAGFHFPSKSSGKSAIQSPPTTNEPHDPVSSQFNTFQFWRNPLPSIESELLELLAADAITVTQKLESVNLSAESEEHEGNNGEQHEEEEEEEFNSDDEEEEEDDEDGGGWITPSNIKQVQMDAGVRGPSADVKVGCVTTDFAMQNVLIQIGLNVLSVNGMLIKNTRSYILRCHACFKTTTNMNKSFCPNCGNNTLKKIAVTLNEDGTMQMHFSRNPKVLNPKGKRYSLPMPQGGKHGNNPHLVEDQRFPQQRMSRKARQKTNVFDPDYLASSSPFSEHDVYSKSASLQLRDGQTGGGRRRTNPNAARKKFVKK-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *****.*****:: *.*::*******:::** *****.*:* **.***:* ****:***:::****:**************:*********:* **..***:**:* .::.*: :****.: *:***:* *. *. : : . * . :*.:* ***.***.*: ** *** : ******* ::.** *************:* : . . **:***:**********:*:**:**:*****::::********.*****::*.: ** :***:****::**:.:***::************:* ***** *:***:. ****.******* *:*:******:** ***:*. *** *:*: *:** **:**. *.**** ****:******* ", "identical_positions": 255, "similar_positions": 96, "identity": "57.82%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3113", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGF7-1", "uniprot_id": "PAN2_MOUSE", "id": "Q8BGF7-1", "name": "PAN2-PAN3 deadenylation complex catalytic subunit Pan2", "aln": "-MNFEGLDPGLAEFSPAMHSTLDP----VLDAHLNPSLLQNVELDPEGVALEALPVQESVHIMEGVYSELHSVVAEVG--VPVSVSHFDLHEEMLWVGSHGGHATSFFGPALERYSSFQVNGG-DDIRQIQSLENGILFLTKNNLKYMARGGLIIFDYL------LDENEDMHSVLLTDNSTLLVGGLQN--HVLEIDLNTVQETQKYAVETPGVTIMRQTNRFFFCGHTSGKVSLRDLRSFKVEHEFDAFSGSLSDFDVHGNLLAACGFSSR-LTGLACDRFLKVYDLRMMRAITPLQVHVDP-------AFLRFIPTYTSRLAIISQSGQCQFCEPTGLANP-ADIFHVNPVGPLLMTFD------VSASKQALAFGDSEGCVHLWTD-----SPEPSFNPYSRETEFALPCLVDSLPPLDWSQDLLPLS-LIPVPLT-TDALLSDWPAANSAPAPRRAPPVDAEILRTMKKVGFIGYAPN----PRTRLRNQIPYRLKESDHEFDNFSQVTESPTGREEEP-LHTVSKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAYCNCMIQVLYFLEPVRCLIQNHLCQK--EFCLACELGFLFHMLDLSRGD-PCQGSNFLRAFRTIPEASALG--LILADSDEASGKGSLARLIQRWNRFILTQLHQDMQEL-EVPQAYRG----------AGG-SFCSS-----------------------GDSIIGQLFSCEMENCSLCR-CGSETVRASSTLLFTLS---YPE----DKTGKNYDFAQVLKRSICLEQNTQAWCDNCEKYQPTIQTRNIRHLPDILVINCEVNSSKEADFWRLQAEVAFKIAVKKYGGEMK-SKEFALADR--------------KELRSPEGFLCSS-IEELKNVWLPFSIRMKMTKNKGLDVCNWADEHELSSLGAPSQWGPARAEEELGVYVYDLMATVVHILDSRTGGSLVAHIKVGETYHQRKEGVTH----QQWYLFNDFLIEPIDKYEAVQFDMNWKVPAILYYVKRNLNSRYNLNIKNPIEAS--VLLAEASLARKQRKT-----------------HTTFIPLMLNEMPQVGDLVGLDAEFVTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQ-GPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRFLIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKYLELSKNGTEPESFHKVLKGLYEKGRKMDWKVPEPE---SQTSPKNAAVFS-VLAL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IE70-1", "uniprot_id": "PAN2_RAT", "id": "Q6IE70-1", "name": "PAN2-PAN3 deadenylation complex catalytic subunit Pan2", "aln": "-MNFEGLDPGLAEFSPAMHSTLDP----VLDAHLNPSLLQNVELDPEGVALEALPVQESVHIMEGVYSELHSVVAEVG--VPVSVSHFDLQEEMLWVGSHGGHATSFFGPALERYSSFQVNGS-DDIRQIQSLENGILFLTKNNLKYMARGGLIIFDYL------LDESEDMHSLLLADNNTLLVGGLQN--HVLEIDLNTVQETQKYAVETPGVTIMRQTNRFFFCGHTSGKVSLRDLRSFKVEHEFDAFSGSLSDFDVHGNLLAACGFSSR-LTGLACDRFLKVYDLRMMRAITPLQVHVDP-------AFLRFIPTYTSRLAIISQSGQCQFCEPTGLANP-ADIFHVNPVGPLLMTFD------VSASKQALAFGDSEGCVHLWTD-----SPEPSFNPYSRETEFALPCLVDSLPALDWSQDLLPLS-LIPVPLT-TDALLSDWPAANSAPAPRRAPPVDAEILRTMKKVGFIGYAPN----PRTRLRNQIPYRLKESDHEFDNFSQVTESPTGREEEP-LHTVSKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAYCNCMIQVLYFLEPVRCLIQNHLCQK--EFCLACELGFLFHMLDLSRGD-PCQGSNFLRAFRTIPEASALG--LILADSDEASGKGSLARLIQRWNRFILTQLHQDMQEL-EVPQAYRG----------AGG-SFCSS-----------------------GDSIIGQLFSCEMENCSLCR-CGSETVRASSTLLFTLS---YPE----DKTGKNYDFAQVLKRSICLEQNTQAWCDSCEKYQPTIQTRNIRHLPDILVINCEVNSSKEADFWRLQAEVAFKIAVKKFGGEVK-SKEFALADR--------------KELRSPEGFLCCSSMEELKNVWLPFSIRMKMTKNKGLDVCNWADEHELSSLGTPSQWGPARAEEEHGVYVYDLMATVVHILDSRTGGSLVAHIKVGETYHQRKEGVTH----QQWYLFNDFLIEPIDKYEAVQFDMNWKVPAILYYVKRNLNSRYNLNSKNPIEAS--VLLAEASLARKQRKT-----------------HTTFIPLMLNEMPQVGDLVGLDAEFVTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQ-GPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRFLIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKYLELSKNGAEPESFHKVLKGLYEKGRKMDWKVPEPE---SQSSPKSKAGLR-PGALGWVG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q504Q3-1", "uniprot_id": "PAN2_HUMAN", "id": "Q504Q3-1", "name": "PAN2-PAN3 deadenylation complex catalytic subunit PAN2", "aln": "-MNFEGLDPGLAEYAPAMHSALDP----VLDAHLNPSLLQNVELDPEGVALEALPVQESVHIMEGVYSELHSVVAEVG--VPVSVSHFDLHEEMLWVGSHGGHATSFFGPALERYSSFQVNGS-DDIRQIQSLENGILFLTKNNLKYMARGGLIIFDYL------LDENEDMHSLLLTDSSTLLVGGLQN--HIIEIDLNTVQETQKYAVETPGVTIMRQTNRFFFCGHTSGKVSLRDLRTFKVEHEFDAFSGSLSDFDVHGNLLAACGFSSR-LTGLACDRFLKVYDLRMMRAITPLQVHVDP-------AFLRFIPTYTSRLAIISQSGQCQFCEPTGLANP-ADIFHVNPVGPLLMTFD------VSASKQALAFGDSEGCVHLWTD-----SPEPSFNPYSRETEFALPCLVDSLPPLDWSQDLLPLS-LIPVPLT-TDTLLSDWPAANSAPAPRRAPPVDAEILRTMKKVGFIGYAPN----PRTRLRNQIPYRLKESDSEFDSFSQVTESPVGREEEPHLHMVSKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAYCNCMIQVLYFLEPVRCLIQNHLCQK--EFCLACELGFLFHMLDLSRGD-PCQGNNFLRAFRTIPEASALG--LILADSDEASGKGNLARLIQRWNRFILTQLHQDMQEL-EIPQAYRG----------AGGSSFCSS-----------------------GDSVIGQLFSCEMENCSLCR-CGSETVRASSTLLFTLS---YPDGSKSDKTGKNYDFAQVLKRSICLDQNTQAWCDTCEKYQPTIQTRNIRHLPDILVINCEVNSSKEADFWRMQAEVAFKMAVKKHGGEISKNKEFALADW--------------KELGSPEGVLVCPSIEELKNVWLPFSIRMKMTKNKGLDVCNWTDGDEM-------QWGPARAEEEHGVYVYDLMATVVHILDSRTGGSLVAHIKVGETYHQRKEGVTH----QQWYLFNDFLIEPIDKHEAVQFDMNWKVPAILYYVKRNLNSRYNLNIKNPIEAS--VLLAEASLARKQRKT-----------------HTTFIPLMLNEMPQIGDLVGLDAEFVTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQ-GPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRFLIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKYLELSKNGTEPESFHKVLKGLYEKGRKMDWKVPEPE---GQTSPKNAAVFSSVLAL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B989-1", "uniprot_id": "A0A8M2B989_DANRE", "id": "A0A8M2B989-1", "name": "PAN2-PAN3 deadenylation complex catalytic subunit PAN2", "aln": "MMNFEGLDPGLGDYAPGLHGGLEPGLDSSLDPRLDPALLQGVEIDP-----DGLAVSESVHIVEGMYSELHSVAAEVG--IPVTATHFDLQEELLWMGNHRGHASSFFGPTMGRYSSFQVHMT-DDIRHIQSMDTGVLFLTKNNLRCLTRGGFIMFDYP------MEEGADMHSLILTENNTLLMGGLQN--YVAELDLTTVQETQKFTVEVPGVAIMRQTSRFFFCGHTSGKVSLRDLRTFKMEHEFDAFSGSLSDFDIHGNLLAACGFSSRGLNGLSCDRFLMVYDLRMMRAVTPLQVHVDP-------LFLRFIPTYTSRLAIISQTGQCQFCEPTGLASL-ADIFHVNTVGQLLMSFD------VSSSKQALSFGDSGGCVHLWSS-----APEVSYNSYSRDTELALPCLVDSLPQMDWNHELMPLS-LLPMPLTSTEPLLSDWPTALIAPSPRRAPPVDPEILRTMKTVGFIGYAPN----PRTRPRNQVPYKIKDVELDYDSYNQVPESPIGRDEEPHLYMVPKKYRKVTIKYSKLGLEDFDFKHYNRTLFAGLEPHIPNAYCNCMIQVLYFLEPIRCLVQNHLCQK--EFCLACELGFLFHMLDLSRGD-PCQASNFLRAFRTIPEASALG--LILADSDEQTGKARLGRLIQSWNRFILAQLHQETLEQ-EGPQAYRG----------ASSSSVLSSS----------------------GESVISRLFGCEVENSSLCC-CGKETVRSSLTLLFTMH---YPEQSSLEKKIEEYEFVDILRKSICLEQSTQAWCDNCEKYQPTVQTRNIRCLPDVLVINCEVNSAKEAEFWKAQTEYVFNKALKKEAAEPPKPKEPLPTEWC-----------LEEELCNVEGLTFDTQAEDMRHVWIPLSLRMCISKAQGLEVSSLTEGEELT-----------ESEEAEGVSIYDLFVTVSHVQDTRTGGNMVAHIKVGETYHQRKEGVTH----QQWYLFNDFLIEPIDKAESVQFDVNWKVPAVLYYIKRNYHTKFDLRIKNPIEAS--VLLTEASLARKQRKS-----------------HATFIPLMVSEMPQVGDLVGLDAEFVTLNQEEAELRSDGTKSTIKPSQMSVARITCVRGQ-GQNEGVPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRFLIDTGVRFVGHGLQKDFRVINLMVPKDQVIDTVYLFHMPRKRMISLRFLAWYFLDLNIQGETHDSIEDARTALQLYRKYLELSHNGGQ-EEFRKVLKALYEKGRKLDWKVPDIDSADGQGSPKSTAVFPSVMGL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7K9-1", "uniprot_id": "PAN2_DROME", "id": "A1Z7K9-1", "name": "PAN2-PAN3 deadenylation complex catalytic subunit PAN2", "aln": "-MDYVYCGTDPIGASEDILSVYDAG-SAPGNGHFSPSFNG-----------------FNIGTTDPEYVELVPVLADGGEHFGVSSVAFDDYEELLWMGNQGGHVTSYYTNSMQKYTSFQVHAT-DIVRDISTLDSGVLALTQTSLRHQIRRGLPKFTFK------SNNMKEMVSMLQLSPHRLVMAGLQD--ELIDFDLRTLKETRIEHVGAGGCTVLRKNSRYLFAGDQLGTVTLRDLNSLSVQHTIKTHTNILSDFSVQGNLLISCGYSGR-QNNLAIDRFLMVYDLRMLRLIAPIQVMIDP-------QMLKFLPSLTSQLAVVSSYGQVQLVDTVELSEPRVSMYQINTNGSQCLSFD------ISSSSQAMAFGDQSGHINMIAAV---QTPQPQFNLYSRSTEFAD--VVPQLPMVSITDTNFPLSSVMLPHLTTGTQWFSDWPEELLRYRYHRPKTIDPEVLSNMKMQGPIGYSPN----PRTARRNQIPYVIEQGG---VCSPNGNGTAAATKAENGVKIIPRRYRKVELKYTKLGTQDFDFDQHNQTCFAGLEATLPNSYCNAMLQILYFTDALRVKLLEHSCIK--EFCLSCELGFLFNMLDKSTASSPCQASNFLRSFRTVPEASALG--LILTD---RSSNVNLISLIQNWNRFILHQMHYEIFDSSKNASTYSGSVQTSTNAENAGSSETSGSSDLYDSISDENSKEDDRERSKINAETDISKIFGTKQICINRCIKCQEEKIKESILLACNLS---YPN--HIKDSDQYFNFGTILKRSLSSEKSIQAFCERCKKFSPTNQSVKVTSLPQILSINCGLNNEKDITFLKRQLNRCSEKTTVDAAASLSTSKPCRYGANCSRSDCHFMHPDRKSPSHTSQPNAVNNSPNGRQKSWFPLTFTMGINDQGEVQVQTQSDASSGKS-EQEEETEKPPTKGLDNNRMYALHAVVCQVDDG-TQKNLVSLINVQRPYHTMKLAESADDPQSQWYIFNDFSISPVSPQESVWFTLDWKVPCILFYRHVEDDSESASTTSSTVTESEETIPSESSSGSPTNLSNPFLEEIVSPMLGNLSADATLQPLQSDEMPQSGDLVAMDAEFVTLNPEENEIRPDGKTATIKPCHMSVARISCIRGQ-GPAEGVPFMDDYISTQEKVVDYLTQFSGIKPGDLDANFSKKRLTALKYSYQKLKYLVDVGVIFVGHGLKNDFRVINIYVPSEQIIDTVHLFHMPHHRMVSLRFLAWHFLGTKIQSETHDSIEDARTTLQLYKHYLKLQ----EEKKFANALKNLYERGKQLQWKVPED-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53010-1", "uniprot_id": "PAN2_YEAST", "id": "P53010-1", "name": "PAN2-PAN3 deadenylation complex catalytic subunit PAN2", "aln": "MNNWQHFFNNPVDLSEHLKKPYFR--------------------------------------FDNRDKE-------------ITAISFDEKANLIWSGDSYGCISSYD-PTFQLYTRYRGHIGGNSVKDILSHRDGILSISEDSLHFANRRGVTKLNLTSIDIAAFSELNTMCYSPHSLKNNIYCGGDNTNWGIASIDLNRGCLDSLLNYSS-KVKLMCSNNKVLSIGRQTGTVDLLDPTSNRTIKSFNAHSASISAMDLRDNTLVTVGKSKR-FYNLYADPFVNVYDLRTMRQLPPVSFSKGTTMGSGGADFVQLHPLLPTVMIVASSSGSFDFIDLSNPTLRTQYVHPCQSIKKLCLSPNGDVLGILEADNHLDTWRRSSNNMGMFTNTPEMLAYPDYFNDITSDGPISVDDETYPLSSVGMPYYLDKLLSAWPPVVFKSEGTIPQLTGKSPLPSSGKLKSNLAVISSQNEKLSTQEFPLLRYDRTKYGMRNAIPDYVCLRDIRKQITSGLETSDIQTYTSINKYEVPPAYSRLPLTSGRFGTDNFDFTPFNNTEYSGLDPDVDNHYTNAIIQLYRFIPEMFNFVVGCLKDENFETTLLTDLGYLFDMMERSHGK-ICSSSNFQASLKSLTDKRQLENGEPQEHLEEYLESLCIRESIEDFNSSESIKRNMPQKFNRFLLSQLIK----------EEAQTVNHN-------------------------ITLNQCFGLETEIRTECS-CDHYDTTVKLLPSLSISGINKTVIKQLNKKSNGQNILPYIEYAMKNVTQKNSICPTCGKTETITQECTVKNLPSVLSLELSLLDTEFSNIR-------------------------------------------------------------SSKNWLTSEFYGSIIKNKAVLRSTAS-----------------ELKGTSHIFKYELNGYVAKITDNNNETRLVTYVKKYNPKEN----------CFKWLMFNDYLVVEITEEEALKMTYPWKTPEIIIYCDAEELRKPFFSVDTYSINYDILFRDYFANGIRDTAR------------------REYKLLTHDEAPKSGTLVAIDAEFVSLQSELCEIDHQGIRSIIRPKRTALARISIIRGEEGELYGVPFVDDYVVNTNHIEDYLTRYSGILPGDLDPEKSTKRLVRRNVVYRKVWLLMQLGCVFVGHGLNNDFKHININVPRNQIRDTAIYFLQ-GKRYLSLRYLAYVLLGMNIQEGNHDSIEDAHTALILYKKYLHLK----EKAIFEKVLNSVYEEGRAHNFKVPETSKG----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . : : : * :: ** :::* *. * :*: :: *: :: : : ::.* : *:* ::: .*: * *. : .: * : .* : : .:** :: ...: : * *.* * * : : :.:.: :* :.::.* * : * * * .* * *: ***** :* :.*:.. .. :::: * .: : : *. *. :: : : :. :. :: : :.:..: :: . . : : : : :* : . :: . *. :. * : :.: . : . . : : . :. .: ** :* : : . :. * :: :. ::* ::*** .*.* ::**:. : * * *.::*: * : : : * * :**:**.*:: * .. *...** :::::.: * . . : *: :* : : . . . :.: *. : . * * . .: . ... : :: :. :: . :: * * * .. * .: **.:* :: : . : : : *:. : : . : . : : * * * :: * . :*: :: .. . :* :***: : : *:: : **.* :: * . : . .. : : . * .* *: * **.:*****:*: * *: :* : *:* : ::***: :**: * *:**:***: . ::: ****::*** *****.: *.*:*. : * *: *:: * ******::**: **: ** :*: **. * :* :***:**: :*. :** .*******:*:* **::**.*. : * :.*: :**.*: ::***: ", "identical_positions": 196, "similar_positions": 326, "identity": "14.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3124", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66X93-1", "uniprot_id": "SND1_RAT", "id": "Q66X93-1", "name": "Staphylococcal nuclease domain-containing protein 1", "aln": "-MASAQSSGSS-----GGPAVPTVQRGIVKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAATQPDGKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDT-NGENIAESLVAEGLAS-RREGMRANNPEQNRLSECEEQAKASKKGMWS-EGNGSHTIRDLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDHYLVTVMLSGIKCPTFRRETDGS---ETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWRDYVPPTANLDQKDKQFVAKVMQVLNADAIVVKLNSGDYKTIHLSSIRPPR-------LEGD-NIQDK--NKKLRPLYDIPYMFEAREFLRKKLIGKKVSVTVDYIRPASPATET-VPAFSERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELLAAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAK-QFLPFLQRAGRSEAVVEYVFSGSRLKLYLPKETCLITFLLAGIECPRGARNLPG--LVQEGEPFSEEATLFTKELVLQREVEVEVESMDKAG-NFIGWLHMD-GANLSVLLVEHALSKVHFTAERSAYYKPLLSAEEAAKQRKEKVWAHYEEQPVEEVMPVLEEKE------RSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRSDISSHPPVEGAYAPRRGEFCIAKF-VDGEWYRARVEKVESPAKVHVFYIDYGNREILPSTRLGALPPAFSTRVLPAQATEYAFAFIQVPQDEDARTDAVDSVVRDIQNTQCLLNVEHLSASCP-HVTLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRADDADEFGYSR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q78PY7-1", "uniprot_id": "SND1_MOUSE", "id": "Q78PY7-1", "name": "Staphylococcal nuclease domain-containing protein 1", "aln": "MASSAQSSGSS-----GGPAVPTVQRGIVKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAATQPDGKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDT-NGENIAESLVAEGLAT-RREGMRANNPEQNRLSECEEQAKASKKGMWS-EGNGSHTIRDLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPGHHLVTVMLSGIKCPTFRRETDGS---ETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNLLGTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWRDYVPPTANLDQKDKQFVAKVMQVLNADAIVVKLNSGDYKTIHLSSIRPPR-------LEGD-NIQDK--NKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVDYIRPASPATET-VPAFSERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELLAAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAK-QFLPFLQRAGRSEAVVEYVFSGSRLKLYLPKETCLITFLLAGIECPRGARNLPG--LVQEGEPFSEEATLFTKELVLQREVEVEVESMDKAG-NFIGWLHMD-GANLSVLLVEQALSKVHFTAERSAYYKPLLSAEEAAKQRKEKVWAHYEERPVEEVMPVLEEKE------RSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDISSHPPVEGSYAPRRGEFCIAKF-VDGEWYRARVEKVESPAKVHVFYIDYGNREILPSTRLGTLPPAFSTRVLPAQATEYAFAFIQVPQDEDARTDAVDSVVRDIQNTQCLLNVEHLSASCP-HVTLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRADDADEFGYSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7KZF4-1", "uniprot_id": "SND1_HUMAN", "id": "Q7KZF4-1", "name": "Staphylococcal nuclease domain-containing protein 1", "aln": "MASSAQSGGSS-----GGPAVPTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAATQPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDT-NGENIAESLVAEGLAT-RREGMRANNPEQNRLSECEEQAKAAKKGMWS-EGNGSHTIRDLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRREADGS---ETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWRDYVAPTANLDQKDKQFVAKVMQVLNADAIVVKLNSGDYKTIHLSSIRPPR-------LEGE-NTQDK--NKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVDYIRPASPATET-VPAFSERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELLAAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAK-QFLPFLQRAGRSEAVVEYVFSGSRLKLYLPKETCLITFLLAGIECPRGARNLPG--LVQEGEPFSEEATLFTKELVLQREVEVEVESMDKAG-NFIGWLHID-GANLSVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQPVEEVMPVLEEKE------RSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKF-VDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCP-HVTLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRADDADEFGYSR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZT42-1", "uniprot_id": "SND1_DANRE", "id": "Q7ZT42-1", "name": "Staphylococcal nuclease domain-containing protein 1", "aln": "MASAVPAQVQS-----SQASAPQLQRGIVKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGALARRAIQGQPDTKDTPDEPWAFQAREFMRKKVIGKEVCFTVENKTPQGREYGMVYLGKDT-SGENIAESLVAEGLAMVRREGIRGNNPEQVRLCDLEDQAKSSKKGLWS-EGGGSHTIRDLKYTIENPRNFVDSLHQKPVNAIIEHVRDGCMVRALLLPDYYLVTVMLSGIKSPTFKREADGS---ETPEPFAAEAKFFTESRLLQRDVQIILESCPNQVILGTILHPNGNITELLLKEGFARCVDWSMAVYTQGAEKLRAAERSAKERKVRIWKDYVAPTANLDQKDRQFVAKVMQVVNADAIVVKLNSGEYKTIHLSSIRPPR-------LEGEEKNKDK--DKRFRPLYDIPYMFEAREFLRKKLIGKKVNVTVDYIRAATNAMEMGVPAFPERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELLAAEARAIKNGKGLHSKKEVPIHRVADISGETQKAK-QFFPFLQRAGRSEAVVEYVFSGSRLKLYMPKETCLITFLLAGIECPRGSRNMPG--GMQVAEPYSEEAMLFTKELVLQREVEVEVESMDIAG-NFIDWLHID-GVNLSVALVENALSKVHFTAERSSYYKTLVSAEESARQRKEKLWANYEEKPNEEVAQVTEAKE------RGRNTDPSTSLEITDGLHFYAQDVETGTKLENLMESMRGEIAAQPPVEGSFAPRRGEFCIAKF-ADGEWYRARVEKVESPAKVHVFYIDYGNREVLSSTRLAALPPAFSTRTLPPQATEYAFAYIQVPQDEDARADAVDSVVRDIHNTQCLLNVEYSGMVCP-QVTLQFADTKEDVGLGLVKEGMVMVDIRKEKYLQKMVTEYLNAQESAKSARLNIWR----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0S7-1", "uniprot_id": "SND1_DROME", "id": "Q9W0S7-1", "name": "Staphylococcal nuclease domain-containing protein 1", "aln": "MATAANTATAAGAAKDAPPAPTKSLSGIVKQVLSGDTVVIR-ATKGAPPPEKQITFSHVLAPKLARRPGAG---GDETKDEPWAWESREFLRKKLIGVEVTFTFDKPANSNREYGFVWIGKDKETGENVVESIVREGLVSVRREGRP--TAEQQTLIELEDQARAAGRGKWSPTASAADKVRNIKWSHENPAHLVDIYGGNPVKAIIEHVRDGSTVRAFLLPDFHYITLMISGIRCPGVKLDADGKPDLSVKVPFADEARYYVETRLLQRDVEIRLESVNNSNFIGTILYPKGNIAESLLREGLAKCVDWSMAVMKTGTDKLRAAERFAKEKRLRQWQDYQAKTPAFNSKEKDFSGTVVEVFNGDAINVRLSNGQVKKVFFSSIRPPRDQRAVVGTDGEEIVKAPPRGKNYRPLYEIPHMFDAREFLRKKLINKKVQCNLDYISPPR-------ENFPEKYCYTVSIGGQNVAEAMVAKGLATCVRYRQDDDQRSSAYDQLIAAEQQAIKGLKGLHAKKDNATLRVNDLTVDHSRIKVQYLPSWQRALRTEAIVEFVASGSRLRIFVPKDSCLVTFLLAGISCPRSSRPALNGVPAQEGEPFGDEALTFTRERVLQRDVSVHIDTTDKAGSSVIGWLWTDSGANLSVALVEEGLAEVHFSAEKSEYYRQLKIAEDRAKAAKKNIWTNYVEEVPKEKTVTEEEKEDKVVAERKVNYENVIVTEITETLTFFAQSVESGSKLESLMSKLHADFQSNPPIAGSYTPKRGDLVAAQFTLDNQWYRAKVERVQG-SNATVLYIDYGNKETLPTNRLAALPPAFSS--EKPYATEYALALVALPTDNEDKEEALRAFSEDVLNHKVQLNVELKVTGSPNLATLRDPTTKVDFGKQLVAEGLVLAEQRGERKLKELVDQYKAAQEAARVAHLAIWKYGDITQDDAPEFR---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. : : . .: . **:* **** ::::* .:*.****:**.:*:: * ****. .:* *****: :***:***:** ** **.:: : ..****::::***. .***:.**:* ***. **** ..** * : *:**::: :* ** ...:..:*::*:: *** ::** :**:*********. ***:***..: :*:*:***:.* .: ::**. .. *** **:::.*:*******:* *** *. ::****:*:***:* **:**:*:*****:** . *::******* ***:::* *:** . *. ::.*:::* ..*::*.*.*** *:*..*: *.:.:******* :*: : .*. ****:**:**:**********.***. .:*** .. *.*: * **:*** *:***:*:***** :*********** **:*:*** :***. ****:**: . ** *:: : .: * *::* *** *:**:**:* *****::::**::**:*******.***.:* . * .**:.:** **:* ****:*.*.::: * ** ..*.** * *.**** ***..*::***:**:* **: * **: *: *:::*::* *. :* . * ** * . . ***: * *:.*.**:*::**.**..:: :: ::**: *:::*:**:: *:* *.:****:**:*:. :: *:******:* *.:.**.:*.****: . *****:* : :* *:: : :*: :. .*: * : **** .* .**: . :* *.* ** **:*:.: * *: ::::: :* ***:*: *:* :*: ", "identical_positions": 411, "similar_positions": 290, "identity": "43.49%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3132", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BJH1-1", "uniprot_id": "ZC21A_MOUSE", "id": "Q8BJH1-1", "name": "Zinc finger C2HC domain-containing protein 1A", "aln": "--------------------------------------------------------------MDGLEENGSVVQVGDLLPCKICGRTFFPLALKKHGPICQKTATK----------------KRKTFDSSRQRAEGTDIPTVKPLKP------------RPEPPKKPSNWRRKHEEFIATIRAAKGLDQALKEGGKLPPPPPPSYDPDYIQCPYCQRRFNENAADRHINFCKEQAARISNKGKFSTDSKGKPAS--RPQ-YKPSPLKKSNPPGIPSSGSSRLPQPSTTSK-TIVGVPTGKASSVNSPLGNKP-----------QTLSPSHRAIAAPQAGANTKARNTTPPSLARNSVAGVLTNKRKTLTENYAARPDGDYTSSVNGGNSKGIEGN-----SSGHLPKFCHECGTKYPVEWAKFCCECGIRRMIL-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AU51-1", "uniprot_id": "A0A8I6AU51_RAT", "id": "A0A8I6AU51-1", "name": "Zinc finger C2HC domain-containing protein 1A", "aln": "WLCKVYSWLRFATSGSPALTDPLGPAPSPASSGQDTHLAYSVLGSLPSISPAPCSGRCLSISQGNAPENGSVVQVGELLPCKICGRTFFPLALKKHGPICQKTATK----------------KRKTFDSSRQRAEGTDIPTVKPLKP------------RPEPPKKPSNWRRKHEEFIATIRAAKGLDQALKEGGKLPPPPPPSYDPDYIQCPYCQRRFNENAADRHINFCKEQAARISNKGKYSTDSKGKPAS--RPQ-YKPSPLKKSNPPASTSSGSSRLPQPSTTSK-TIVGVPTGKASSVNSPLGNKP-----------QTLSPSHRALAAPQAGANTKSRNTTPPSLARNSVAGVLTNKRKTFTESYAARPDGDYTSSVNGGNIKGIEGN-----SSGHLPKFCHECGTKYPVDWAKFCCECGIRRMIL-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96GY0-1", "uniprot_id": "ZC21A_HUMAN", "id": "Q96GY0-1", "name": "Zinc finger C2HC domain-containing protein 1A", "aln": "--------------------------------------------------------------MEGLEENGGVVQVGELLPCKICGRTFFPVALKKHGPICQKTATK----------------KRKTFDSSRQRAEGTDIPTVKPLKP------------RPEPPKKPSNWRRKHEEFIATIRAAKGLDQALKEGGKLPPPPPPSYDPDYIQCPYCQRRFNENAADRHINFCKEQAARISNKGKFSTDTKGKPTS--RTQVYKPPALKKSNSPGTASSGSSRLPQPSGAGK-TVVGVPSGKVSSSSSSLGNKL-----------QTLSPSHKGIAAPHAGANVKPRNSTPPSLARNPAPGVLTNKRKTYTESYIARPDGDCASSLNGGNIKGIEGH-----SPGNLPKFCHECGTKYPVEWAKFCCECGIRRMIL-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXT7-1", "uniprot_id": "ZC21A_DANRE", "id": "Q7SXT7-1", "name": "Zinc finger C2HC domain-containing protein 1A", "aln": "--------------------------------------------------------------MEEIEE--SPPTSEELVPCKICGRSFFPKVLKKHVPICQKTAAK----------------RRKVFDSGRQRAEGTEISTVKPIKPKLQSSSSSSKSDKPEPPKKQSNWRRKHEEFIATIRAAKSINQVIKDGGPLPPPPPPSYDPDYIQCPYCQRRFGENAADRHIKFCKEQASRISNKSKLAGGDKTKPPA--RTQ-YKPPAPKKANSP-TASSVSSRLPQRSAYGQGAGTGIPSSKPSSTGSIKSTPSG---------YSPLRNNSSSLTSPPSEGNMKPKGMVSQSSLRNPSTGIGMNKKK-------IQNADNCISRNDMKNENDFNYS-----TTG--TKFCHECGTKYPVESAKFCCECGVKRMYI-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1M553-1", "uniprot_id": "F1M553_RAT", "id": "F1M553-1", "name": "", "aln": "--------------------------------------------------------------MAEAQLVVSDGNQ-KLFPCEVCGRCFATDVLERHGPICIKLFNK----------------KRKPFNSLKQRLQGTDIPTVSKAPQ------------SKAQPMRKSNWRQQHEDFINAIRLAKQCTLALKEGQPLPPPPPPTINPDYIQCPYCMRRFNETAAQRHINFCKNQTSRRVFD---SNQMAARLAA--RAQGKAPASPKK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D534-1", "uniprot_id": "ZC21B_MOUSE", "id": "Q9D534-1", "name": "Zinc finger C2HC domain-containing protein 1B", "aln": "--------------------------------------------------------------MGEAQLLVEDGNQ-KLFPCEVCGRCFATDVLERHGPICKKVFNK----------------KRKPFNSLKQRLQGTDIPTVGKSPQ------------PKVQPVRKSNWRQQHEDFINTIRSAKQFTLAIKEGRPLPPPPRPTSNPDYIQCPYCMRRFNETAAQRHINFCKNQTSRPVFD---PIQMAARLVS--RAQCKAQASLKK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TFG8-1", "uniprot_id": "ZC21B_HUMAN", "id": "Q5TFG8-1", "name": "Zinc finger C2HC domain-containing protein 1B", "aln": "--------------------------------------------------------------MAGAEPFLADGNQ-ELFPCEVCGRRFAADVLERHGPICKKLFNR----------------KRKPFSSLKQRLQGTDIPTVKKTPQ------------SKSPPVRKSNWRQQHEDFINAIRSAKQCMLAIKEGRPLPPPPPPSLNPDYIQRPYCMRRFNESAAERHTNFCKDQSSRRVFN---PAQTAAKLAS--RAQGRAQMGPKK--EPTVTSAVGALLQNRVLVAT----------------------------------NEVPTKSGLAMDPASG-AKLRQGFSKSSKKD------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KGL2-1", "uniprot_id": "A0A0B4KGL2_DROME", "id": "A0A0B4KGL2-1", "name": "C2HC/C3H-type domain-containing protein", "aln": "------------------MLQATDGDEDVDGELLQYDFESELGQDHILPLKLNESWAARRLMEALSHLPPSGNSSTNSAPMRFQQRTQQEQEVRRRELMSTKSSAENLATGAPSAATTRLIGNGKVRQMFDERRRGAGIDRSNPLKPIGTLPSPPAQTKSRPQPPMQRLVKGVADLTMRDAPNAPGRRITSDSNNNKFATPRGTLNRNLKPVVTRKTPPAQETTLHQRSPAPQRSPKIQATQRVSGGTGAAPTAGRLSPPFVRRAEPKSPVKKVNMDTTTAIPEGTALCRYCGRHFNTDRLAKHEEVCQRMLTTKRKIFDASKQRIEGTEAAAFNMKSKGNRNRSTYSSAAQQKGLTTGVKKNNWRKKHEDFIQSIRAAKQVKAHLARGGKLSDLPPPPPSENPDYVQCPHCGRRFNEQAAERHIPKCVNMVHNKPRNGPPAKRR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * .. * :.:: :. * . . * . :* .*: * * : : : * . ... ..* : : : : :: :: . . :::.: . : . * ", "identical_positions": 11, "similar_positions": 42, "identity": "2.47%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3135", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A3KGB4-1", "uniprot_id": "TBC8B_MOUSE", "id": "A3KGB4-1", "name": "TBC1 domain family member 8B", "aln": "MWLKPEEVLLKNALKLWLMERSNEYFVLQRRRGYGEEGGGGLTGLLVGTLDSVLDSTAKVAPFRILHQTPDSQVYLSIACGANREEITKHWDWLEQNIMKTLSVFDSNEDITNFVQGKIRGLIAEEGKQSFAKEDDPEKFREALLKFEKSFGLPEQEKLVTYYSCSYWRGRVPCQGWLYLSTNFLSFYSFLLGSEIKLIISWDAISKLEKTSTVILTESIHVCSQGENHYFSMFLHINETYLLMEQLANYAIKRLFD----------KETFDNDPVLDDPLQITKRGLEYRAHSEQFKAFFRLPKEETLKEVHECFLWVPFSHFSSHGKMCISENYICFASQDGNLCSVIIPLREVLAIDKTDDSNR----SVIISIKGKTAFRFSELKDFEQLVAKLRLKCRAASTQ-DDVSTEVAVSSDSTGPSENFEEQPLTCPKECSKTVNTEALMTVFHPQNLENLDSKMLKEKMKEQSWNILFSECGRGVSMFRTKKTRDLVVRGIPETLRGELWMLFSGAVNDMATNPGYYAEVVEQSLGTS-NLATEEIERDLRRSLPEHPAFQSDTGISALRRVLTAYAYRNPKIGYCQAMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNRRIIG----ALVDQAVFEELIRDHLPQLTDHMTDMTFFS-SVSLSWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAILDYNLDKLLTCKDDAEAVTALNRFFDNVINKDSPLPSNVQQGSNISNEKSDHTKVDITDLIKESNEKYGS-IRYEDIHSMRCRNRLYVIQTLEETTKQNVLRVVSQDVKMSLQELDELYVIFKKELFISCYWYL---------------------SCPGLKHHDPSLPY---------LEQYQIDCQQFRVLYHLLSPWAHSANRDSLALWT--FRLLDENSDCLINFKEFSSAID----IMYNGSFTDKLKLLFKLHIPPAYTEVMSKTSSKGDELSTEELLYFSQLQVSKPADEKETESGRNSP---------------------------------------------------------------------EKGKGKIDIQAYLSQWQ--------------------------------------------------------------DELLKKEETIKDLPRMNQSQFIQ------FSKTLYNLFHEDPEEESLYQAIAIVTNLLLRMEEVGRKLHS----------PASSAS----TARDSG-PSEGNAESSVKKD-LPSPREEHQ------------------------------------------------WSFAFEQILASLLNEPALVRFFERPLDLKAKLENAKSSQLRSRTKM-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K9M5-1", "uniprot_id": "A0A0G2K9M5_RAT", "id": "A0A0G2K9M5-1", "name": "TBC1 domain family member 8B", "aln": "MWLKPEEVLLKNALKLWLMERSNEYFVLQRRRGYGEEGGGGLTGLLVGTLDSVLDSTAKVAPFRILHQTPDSQVYLSIACGANREEITKHWDWLEQNIMKTLSVFDSNEDITNFVQGKIRGLIAEEGKQSFAKEDDPEKFREALLKFEKSFGLPEQEKLVTYYSCSYWRGRVPCQGWLYLSTNFLSFYSFLLGSEIKLIISWDAISKLEKTSSVIVAESIHVCSQGENHYFSMFLHINETYLLMEQLTNYAIKRLFD----------KETFDNDPVLDDPLQITKRGLEYRAHSEQFKAFFRLPKEETLKEVHECFLWVPFSHFSTHGKMCISENYICFASQDGNLCSVIIPLREVLAVDKTDDSSR----SVIISIKGKTAFRFNEVKDFEQLVAKLRLKCRAASTQ-DDGSTEVAISSDSTGLSENFEEQPLTFPKECSKTVNTEALMTVFHPQNLENLDSKMLKEKMKEQSWNILFSECGRGVSMFRTKKTRDLVVRGIPETLRGELWMLFSGAVNDMAANPGYYAEVVEQSLGTS-NLATEEIERDLRRSLPEHPAFQSDTGISALRRVLTAYAYRNPKIGYCQAMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNRRIIGKNKCALVDQAVFEELIRDHLPQLTDHMTDMTFFS-SVSLSWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAILDYNLDKLLTCKDDAEAVTALNRFFDNVINKDSPLPSNVQQGSNINDGKSNHAKVDITDLIRESNEKYGS-IRYEDIHSMRCRNRLYVIQTLEETTKQNVLRVVSQDVKMSLQELDELYVIFKKELFISCYWYL---------------------SCPGLKHHDPSLSY---------LEQYQIDCQQFRVLFHLLCPWAHSANRDSLALWT--FRLLDENSDCLINFKEFSSAID----IMYNGSFTEKLKLLFKLHIPPAYTEVISKTSSKGDELSTEELLYFSQLQVSKPADGKETELGRKSP---------------------------------------------------------------------EKGKGKIDIQAYLSQWQ--------------------------------------------------------------DELLKKEENIKDLPRMNQSQFIQ------FSKTLYNLFHEDPEEEALYQAIAIVTNLLLRMEEVGRKLHS----------PASSAKGLSSVACDSG-PSEGNTESSVKKD-PSSPREEHQ------------------------------------------------WSFAFEQILASLLNEPALVRFFERPLDLKAKLEKAKSSQLRSRTKM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0IIM8-1", "uniprot_id": "TBC8B_HUMAN", "id": "Q0IIM8-1", "name": "TBC1 domain family member 8B", "aln": "MWLKPEEVLLKNALKLWLMERSNDYFVLQRRRGYGEEGGGGLTGLLVGTLDSVLDSTAKVAPFRILHQTPDSQVYLSIACGANREEITKHWDWLEQNIMKTLSVFDSNEDITNFVQGKIRGLIAEEGKHCFAKEDDPEKFREALLKFEKCFGLPEKEKLVTYYSCSYWKGRVPCQGWLYLSTNFLSFYSFLLGSEIKLIISWDEVSKLEKTSNVILTESIHVCSQGENHYFSMFLHINQTYLLMEQLANYAIRRLFD----------KETFDNDPVLYNPLQITKRGLENRAHSEQFNAFFRLPKGESLKEVHECFLWVPFSHFNTHGKMCISENYICFASQDGNQCSVIIPLREVLAIDKTNDSSK----SVIISIKGKTAFRFHEVKDFEQLVAKLRLRCGAASTQYHDISTELAISSESTEPSDNFEVQSLTSQRECSKTVNTEALMTVFHPQNLETLNSKMLKEKMKEQSWKILFAECGRGVSMFRTKKTRDLVVRGIPETLRGELWMLFSGAVNDMATNPDYYTEVVEQSLGTC-NLATEEIERDLRRSLPEHPAFQSDTGISALRRVLTAYAYRNPKIGYCQAMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNRRIIG----ALVDQAVFEELIRDHLPQLTEHMTDMTFFS-SVSLSWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAILDYNLDKLLTCKDDAEAVTALNRFFDNVTNKDSPLPSNVQQGSNVSDEKTSHTRVDITDLIRESNEKYGN-IRYEDIHSMRCRNRLYVIQTLEETTKQNVLRVVSQDVKLSLQELDELYVIFKKELFLSCYWCL---------------------GCPVLKHHDPSLPY---------LEQYQIDCQQFRALYHLLSPWAHSANKDSLALWT--FRLLDENSDCLINFKEFSSAID----IMYNGSFTEKLKLLFKLHIPPAYTEVKSKDASKGDELSKEELLYFSQLHVSKPANEKEAESAKHSP---------------------------------------------------------------------EKGKGKIDIQAYLSQWQ--------------------------------------------------------------DELFKKEENIKDLPRMNQSQFIQ------FSKTLYNLFHEDPEEESLYQAIAVVTSLLLRMEEVGRKLHS----------PTSSAKGFSGTVCGSGGPSEEKTGSHLEKD-PCSFREEPQ------------------------------------------------WSFAFEQILASLLNEPALVRFFEKPIDVKAKLENARISQLRSRTKM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0R0W9-1", "uniprot_id": "TBC8B_DANRE", "id": "B0R0W9-1", "name": "TBC1 domain family member 8B", "aln": "MWLKPEEVLLKNALKLWVTEKSNDYFVLQRRRGYGEDSGG-LTGLLVGTLDTVLDSTAKVAPFRILHQTPDSQVYWTIACGASLEEISQHWDWLQQNIVRTLSVFDSGEDITSFVQGKIRGLIAEEG-TSAGDEEDPERFREAVLRFERLFGLPQREKLVTYFSCSYWRGRVPNQGWIYLSTNFLCFYSYMLGNEVKLVYPWDEVSRLERTSSVLLAESIRVRVRGEDHFFSMLLRLQQTYLIMQQLADYAIVRFFD----------KETFHAEHPLANPLHITQRALEIHARNQSFRSFFRLPQEENLCEVYESFLWVPFSHVNTLGKICVSENYLCFASQDGSQCHLIIPLWEVFSVELPDRSSR----ALTVCLRGKRALRFSEVRDFERLAATIRRKCGTLGSP------QHCIT--------NPDEEGVMVGQ--SQAVSTEALMNVFHPHDAENLDPKMLKERMKEQSWQIHFAEYGRGTGMFCTKKTRDLIVRGVPETLRGELWMLFSGAVHDMISHPGYYGRLLEDCMGSS-SLACDEIERDLHRSLPEHPAFQSDTGISALRRVLTAYAHRNPKIGYCQAMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNRRIIG----ALVDQAVFEELIREHLTQLTEHMTDLSFFS-SVSLSWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAVLDYNMDNLLCCNDDAEAVTVLNRFFDSVTNKDSPLPATVQQASATANDKS-IQKVDISDLIKEAYEKYGD-IRTEEVENMRKRNKLYVIQTLEDTTKQNVLRVVAQDVKFSASQLDELYLLFK--------------------------------------NHDPSLPY---------LDQYQLDQSQFSSLFNLLQPWTTHTHSRSLARSA--FHLLDENGDGLVNFKEFICGLD----ILYNRSFTEKLKLLFKLHLQP---------------------------------DSAEDGVIRKCP---------------------------------------------------------------------ERGRAKVDLQEYLKQWQ--------------------------------------------------------------EDLQRREENIKDLPRINQVQFIS------LTKTLYSVFHGDEEEESLYRAVARVTSLLLRMEEVGRKLQDSSPQKTPQTTPTSTSQPESSPTKPTSPESETPAESRSTHDQPESPVSQHETAPSHSDITPNSTSHPSTPTSSPTETSSPVLDTPTDTPSSPCTVRDGDWSFSFEQILASLLNEPSVVRFFERVVNTDTLITRARKNQLKDAH---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VP46-1", "uniprot_id": "Q9VP46_DROME", "id": "Q9VP46-1", "name": "", "aln": "MWIQPKELLLP--SAFWIAEMHSRYFVLQKRRGHGE--SRGFGSMLVGTYDSVMN--TKPAPYRILHQTPSSEVSYEIAIGITQDEIVKDWEWLKANLFKVLDEMENEDEVTNFTICKIQSLYTQNNQDDTG---ESADFKVMKSKFRQIFKMPEEERLVISYSATYVKNKIPRQGQLYISLNHVCFYSYMLGQEIKRIIRFAELEDISRNANTIYLKTTNNMTYN----FTMLFNASDAHLLIEQLNKMAIQQLIHDPDSPVVDHDTSNFSRLGSKTSKKPVLLRDLTARQKSEEFRIYFRLPQSEIIDGKIKANIWTPYSKRFNSGFIYLSPNFFCFRSDVKDLVSVVIPMKTIKSVEKKDDGQQRFENQIVIITSENVPFMFAHIVDRAVLISKITDLLARVHVP--------------------------LSRERAKYDISWSKQTALMNTFKTQFSAEIIQKQEEKMVRWEAHFRDFGRGIGMFRTTDVINLIVEGIPDKLRQEIWLIFSGAIHDKEMNPGLYEDLVEKAACIKNCFAHDEIDRDLPRSLPEHPAFQSTDGIGALRRVLQAYALRNPQVGYCQAMNIVSSVFLLFCDEENAFWMLASLCENLLPDYYKDKVVG----AQIDQGVLNELVETHLPDLHGHLEQLGVIK-MISISWFLTIFMSVISYESSLHILDCFFYEGAKIIFMISLQIIEWNRDKLLICQDDGEAMLVLQNYLEGVYNPEYQVPPTTDK----RKMERKVQTQTVQTLIHEAYTKFGEDITQQRIEELRNKHRRLTMRQFDIDNEKTIVKAYVQNPYFNRSELHMLLTIIREEKHALKSLQQQQQKVQ--CPLSETPQLVPQSTSRPIQDAGASGGR---------YEAYSVSYEVFHTLFTELTPWRKCVSVD-IGEKL--FRLTDKKGTGVLDFGQLINALG----LVCSNKNMEKLKLLYVLHLPPLLSKAEIERSRRPRPRTKDDAEEAFEAEDFFDNDASESMEALPSPSDHNFDADDFALISATQHLHNLAGISGNTFMDLSRTPNLSVNSNTSSLAHRSSTFYVDLPGFQGTATSTDAGRDEDELQRQLRQQGRYESIDTFSDISDLGAARITPPEAGVGADVVAGAASSAAADHMLLNVETISNFSQISDLVAATRLERVDSNATDLRSLGSLGYLLDQPDEGASNSQHSIPHMRKENFQLLWRSIIEIMGLVQDEEMQRAYENLLELGNSNIKKEPSLESFTQLNMGGDEQPDSNGNPTTPAPEPIGTTRLFVALEEELRQASGKSRTTTTSSGDSSSTN-----------------ISESWHISITQFIATVLTVNSIVRGFQTPIQISEQIEQLQKKRRKCLSTNY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53258-1", "uniprot_id": "GYP2_YEAST", "id": "P53258-1", "name": "GTPase-activating protein GYP2", "aln": "----------------------MSFFDSLRQK----------APFLDKLADSFTPTLTRDEKFRLKYKLPAN-----------------------------ENILEDTNAEVSFATSIKDGKGHSDRVNNKG-----------------------------------RKTAYVYSGRLFLTPHFLVFRDAFDHSSCVLILNISTIKRVERSPSESY-----------------------------------------------------EFALLVTLYTGAKVLIQFIGIRYRSEQFCDKLKLNLKENIPN-------------------------------------------------------------------AKTLPAFLETSYSEFLIAKNILGKKDITVP-----------------------------------------RAGLGQHFKYPGNPTMVKEKAKLRLWFDYFRENGRNLAVVQTPMFRKLIRIGVPNRMRGEIWELCSGAMYMRYANSGEYERILNENAGKT-SQAIDEIEKDLKRSLPEYSAYQTEEGIQRLRNVLTAYSWKNPDVGYCQAMNIVVAGFLIFMSEEQAFWCLCNLCDIYVPGYYSKTMYG----TLLDQRVFESFVEDRMPVLWEYILQHDIQLSVVSLPWFLSLFFTSMPLEYAVRIMDIFFMNGSITLFQVALAVLKINADDILQADDDGMFIAIIKHYFQTLGQSAHPDSSDIKYR----------QITKFQELLVTAFKEFSV-ISEEMAMHARHKYEKGIFQNIETFMKRTQLRHMPKTFNLSSDDLSNIYDMFYQSIETYKISMGTGSSNMGFEVFIQFLSKFCDSCRPCEKDKDPAFRKQKRNFLQRLFDNWDSAHIGELTLNDVVTGLDKLVTVDLLQAINYFFSLYDTDGDGELHREEVLQLSEGLLLLTEPWKSGRYVDLLTKKRIEDDIAENIIKESGGEIATMNQIELPTGVTIDEEKYKVEQAERYLKAASN----------------------------------------------FLQRSFEYAKAVDLAEEVNLIDLSDDEGEEKRTVKQKQ-------------------------------------------------------LESIKANAALDPTHPKVIDLPTFRMIILADETYELFFSNTLRSSVHVDEHVNIDNKNKVLRSMFDGILADGKRVAEQVRRRVDSVATRSSIASVESTPTAAASSITTKEEKYDDLDDFTSEHQPENEE------------------------------------------------LLQSSWFEIDDANETSTKAIQERSFEPLSANSSEEKSNLIEFEA--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* ::: :* *:. :: :*: :: * . . ::. : ..*. . .: . : .* :::: :.: * . : .. : :. :.:... * : : : : :.:.* ::* * : : * . * :. : : *:. * * * : **. .:. * .*: *:*: :* *:* : ***: :.. * :::. * :**::** *****:.*:*: ** **.** **: :**.:********: : :*:: .**:*** * :*: :*.*:. : * : :** *::.::. ::. * :: : . :*:.***::*:: :. * ::.::* ** :* :: :.* ::. * *.:* ..**. : ::.::: : : .. . . *: : ::. * : * : . :: :: ::. :: : :. .:* : :: . ..: : :. * : . : * * * .. :. :. : . :.** :: . : .. : . : : : : * * . . ** : ::: . * . : * .. . . . . : : . : : .: . .. ", "identical_positions": 108, "similar_positions": 250, "identity": "7.86%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3143", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P02651-1", "uniprot_id": "APOA4_RAT", "id": "P02651-1", "name": "Apolipoprotein A-IV", "aln": "MFLKAVVLTVALVAITGTQAEVTSDQVANVMWDYFTQLSNNAKEAVEQLQKTDVTQQLNTLFQDKLGNINTYADDLQNKLVPFAVQLSGHLTKETERVREEIQKELEDLRANMMPHANKVSQMFGDNVQKLQEHLRPYATDLQAQINAQTQDMKRQLTPYIQRMQTTIQDNVENLQSSMVPFANELKEKFNQNMEGLKGQLTPRANELKATIDQNLEDLRSRLAPLAEGVQEKLNHQMEGLAFQMKKNAEELQTKVSTNIDQLQKNLAPLVEDVQSKLKGNTEGLQKSLEDLNKQLDQQVEVFRRAVEPLGDKFNMALVQQMEKFRQQLGSDSGDVESHLSFLEKNLREKVSSFMSTLQKKGSPDQPLALPLP----EQVQEQVQEQVQ-PKPLES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06728-1", "uniprot_id": "APOA4_MOUSE", "id": "P06728-1", "name": "Apolipoprotein A-IV", "aln": "MFLKAAVLTLALVAITGTRAEVTSDQVANVVWDYFTQLSNNAKEAVEQFQKTDVTQQLSTLFQDKLGDASTYADGVHNKLVPFVVQLSGHLAQETERVKEEIKKELEDLRDRMMPHANKVTQTFGENMQKLQEHLKPYAVDLQDQINTQTQEMKLQLTPYIQRMQTTIKENVDNLHTSMMPLATNLKDKFNRNMEELKGHLTPRANELKATIDQNLEDLRRSLAPLTVGVQEKLNHQMEGLAFQMKKNAEELQTKVSAKIDQLQKNLAPLVEDVQSKVKGNTEGLQKSLEDLNRQLEQQVEEFRRTVEPMGEMFNKALVQQLEQFRQQLGPNSGEVESHLSFLEKSLREKVNSFMSTLEKKGSPDQPQALPLPEQAQEQAQEQAQEQVQ-PKPLES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06727-1", "uniprot_id": "APOA4_HUMAN", "id": "P06727-1", "name": "Apolipoprotein A-IV", "aln": "MFLKAVVLTLALVAVAGARAEVSADQVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEVNTYAGDLQKKLVPFATELHERLAKDSEKLKEEIGKELEELRARLLPHANEVSQKIGDNLRELQQRLEPYADQLRTQVSTQAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKVNSFFSTFKEKESQDKTLSLPELEQQQEQQQEQQQEQVQMLAPLES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6Q788-1", "uniprot_id": "APOA5_HUMAN", "id": "Q6Q788-1", "name": "Apolipoprotein A-V", "aln": "MASMAAVLTWALALLS----AFSATQARKGFWDYFSQTSG-DKGRVEQIHQQKMAREP-ATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQ----GLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFAGT-----GTEEGAGPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQLAPPP---PGHSAFAPEFQQTDSGKVLSKLQARLDD-------LWEDITHSLHDQGHSHLG--DP---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HH61-1", "uniprot_id": "A0AC58HH61_DANRE", "id": "A0AC58HH61-1", "name": "", "aln": "-MMWISDSTALPTGLWVSTTAVTSPCYINIDWNYSPSHLFLNRTASIKAKQHRLAASV----------------NIMKVLVVFALAVFTGCQAN-LFYADEPKPQLEQLTDAFWSYVSKATQTAEETVKMIRE------SQLGQEVNERLTQSADMASEYAVVLKKQVDPLTEELMNKITKETEVLRERLGQDLINVREKLEPYADNMKSQIQQRVEELRAAMAPYADSLDS------ETLKATLLQKSEELRGNLEQSVKELQVQLEP------------------YTAELKEKVDQHLQEFQKTVTPLTEDLQVQIRERAQMVQQSLTPYAEDLKEKLDPYAQNLKDQLASLYESYTKRN----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : .:: . *:* .. : : :: :: . . : * : : : :**:: : .: :. : .:. ::: :* :: : : : : .:. : *: :. :. .: : * *:.: * : :::*: :** : : * : ::: *: .:. . .:*: .* * .: *::: *:: . : : :. : .:*.* . . : : : . .. .. : ", "identical_positions": 23, "similar_positions": 106, "identity": "5.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3149", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GLX4-1", "uniprot_id": "A0A8I6GLX4_RAT", "id": "A0A8I6GLX4-1", "name": "Disks large homolog 5", "aln": "MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAG--GAKAELLLQLLLAKEQDHFQDLRAALEKTQPHLLPILYLNGVVGPPQSTEGAGSTYSVLSIMPSDSESSS-SLSSVGTTGKAPSPPPLLTEQQANDKVENLSIQLRLMTRERNELRKRLAFATHGATFDK-RPYHRLNPDYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTQLKDDVDMLRRENGKLRRERNLLQQSWEDMKRLREEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAMDKLEVVKKDYDALRKR--YSEKVAMHNSDLSRLEQLGEENQRLQKQTEMLTQQRDTAIQLQHQCALSLRRFETIHHELSKATAQNKDLQWEMELLQSELTELRSKQVKTAKESEKYKEERDAVYSEYKLIMSERDQVISELDKLQTEVELAESKLKSSTSE--KKAASEEVEALR-----------------------------------------------------------------------------QIKDTVTMDAGRANKEVEVLRKQCKALCQELKEALQEADVAKCRRDWAFRERDKIVAERDSIRTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMECQLEKEARFRQLMAHSSHDSAIDTDSMEWETEVVEFVRETEDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADGRLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPLHINLSGQKDSGISLENGVYAAAVVPGSP----AAKEGSLAVGDRIVAINGIALDNKSLNECESLLRSCQDSLTLSLLKVFPQSSSWSGQNIFENIKDSDRMLSCRAHGPEVQAHNKRNLLQHNNSTQTDIFYTDRLEDRKELDHSGGSSSYLYKPFSGASSPASPQACPSTSERSLNSFRSDTSAERGYGLVDVQSQRPLLSFETEVGPCGTVGAPLDKIDPEGSNSGGTWPKAVLG---STSGPEKLSVYKKPKQRKSIFDPNTFKRPQTPPKVDYLLPGLGLTHSPQPSKRADTPKGSLTPPKPPRRSDSIKFQHRLETSSESEATLVGSSPSTSPPSAPPPSMDPSEPMHASPPRKARVRIASSYHSEGDGDTSYLPVKKPCDEDLTSQKVDELGQKRRRPKSAPSFRPKISPVVIPAQCLEEQDCAPVSGELSPEAQDWSPYTLGHASRPGNPLLYPNRPSVGTVPRSMTPSTTVSSILRNPIYTVRSHRVVPCGSPPVPRDAGSHSLSSSVQHQGRLSLDLSHRACSDYS----EMRASQGSNSLPSSARLGSSSNLQFKAERIKIPLTPRYPRSVMGSDRGSLSHSECS-----TPPRSPLNVDALSFCS-QPQTSASTLPRIAVNSSSHGERRKDR--------------------------PFVEEPRHVKVQKGSEPLGISIVSGEKGG-IYVSKVTMGSIAHQAGLEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNP------------------HIHQLNSHSRSSSHLDPAAAPHSTLQGSSAATPEHPSVIDPLMEQ-----------------DEGPGTPPAKQSTPS------SRIVGDASKKTPEPR-----------IVFIKKSQLDLGVQLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGNLDMRSRTLEDVYVEMMKPKDSIRLKVQYRHEEFTRVKGLSGDSFYIRALYDRLAEVEP-ELSFKKDDILYVDDTLPQGMFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDN-TAKMLSAAARRSFFRRKHKHKRSGSKDSKDLLSLDTFSNDSIP----LFEDSVSLAYQRVQKVDCTSLRPVLILGPLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNR-HCLLDIAPHAIERLHHMHIYPIVIFIRYKSAKHIKEQRDPVYLRDKVTQRHSKEQFETAQKIDQEYSRYFTGVVQGGALSSICTQILAMVSQEQSKVLWIPACPP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q9R9-1", "uniprot_id": "DLG5_MOUSE", "id": "E9Q9R9-1", "name": "Disks large homolog 5", "aln": "MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAG--GAKAELLLQLLLAKEQDHFQDLRAALEKTQPHLLPILYLNGVVGPPQSTEGAGSTYSVLSIMPSDSESSS-SLSSVGTTGKAPSPPPLLTEQQANDTVENLSIQLRLMTRERNELRKRLAFATHGATFDK-RPYHRLNPDYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTQLKDDVDMLRRENGKLRRERNLLQQSWEDMKRLREEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAMDKLEVVKKDYDALRKR--YSEKVAMHNSDLSRLEQLGEENQRLQKQTEMLTQQRDTAIQLQHQCALSLRRFETIHHELSKATAQNKDLQWEMELLQSELTELRSKQVKTAKESEKYKEERDAVYSEYKLIMSERDQVISELDKLQTEVELAESKLKSSTSE--KKAASEEMEALR-----------------------------------------------------------------------------QIKDTVTMDAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSIRTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMECQLEKEARFRQLMAHSSHDSAIDTDSMEWETEVVEFERETEDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADGRLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPLHINLSGQKDSGISLENGVYAAAVVPGSP----AAKEGSLAVGDRIVAINGIALDNKSLNECESLLRSCQDSLTLSLLKVFPQSSSWSGQNIFENIKDSDRMLSCRAHGPEVQAHNKRNLLQHNNSTQTDIFYTDRLEDRKELGHSGGSSSFLHKPFSGSSSPVSPQACPSTSERSLNSFRSDTSAERGYGLVDMRSQRPLLSFETEVGPCGAVEVPLDKIDPEGSNSGGTWPKAVLG---STSGPEKLSVYKKPKQRKSIFDPNTFKRPQTPPKIDYLLPGPGLTHSPQPSKR----VGSLTPPKPPRRSDSIKFQHRLETSSESEATLVGSSPSTSPPSAPPPSMDPSEPTHASPPRKARVRIASSYHSEGDGDTSYLPAKKPCDEDLTSQKVDELGQKRRRPKSAPSFRPKISPVVIPAQCLEEQECVPAIGELSPEGQEWSPYSPGHASRHGNPLLYPNRPSVGTVPRSMTPGTTVGSILRNPIYTVRSHRVLPCGSPPVPRDAGSQSLSPSVQHQGRLSLDLSHRACSDYS----EMRASQGSNSLPSSARLGSSSNLQFKAERIKIPLTPRYPRSVMGSDRGSLSHSECS-----TPPRSPLNIDTLSSCS-QPQTTASTLPRIAVNPSSHGERRKDR--------------------------PFVEEPRHVKVQKGSEPLGISIVSGEKGG-VYVSKVTLGSIAHQAGLEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNP------------------HIHQLNSHSRSSSHLDPAATPHSTLQGSSAGTPEHPSVIDPLMEQ-----------------DEGPGTPPAKQSASS------TRSVGDTTKKTPDPR-----------IVFIKKSQLDLGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDMRSRTVEDVYVEMLKPKDSLRLKVQYRHEEFTRVKGLPGDSFYIRALYDRLAEVEP-ELSFKKDDILYVDDTLPQGVFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDN-TAKTLSAAARRSFFRRKHKHKRSGSKDGKDLLALDTFSNDSIP----LFEDSVSLAYQRVQKVDCTSLRPVLLLGPLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNR-HCLLDIAPHAIERLHHMHIYPIVIFIRYKSAKHIKEQRDPVYLRDKVTQRHSKEQFETAQKIDQEYSRYFTGVVQGGALSSICTQILAMVSQEQSKVLWIPACPP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDM6-1", "uniprot_id": "DLG5_HUMAN", "id": "Q8TDM6-1", "name": "Disks large homolog 5", "aln": "MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAG--GAKAELLLKLLLAKERDHFQDLRAALEKTQPHLLPILYLNGVVGPPQPAEGAGSTYSVLSTMPSDSESSS-SLSSVGTTGKAPSPPPLLTDQQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDK-RPYHRLNPDYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRLKDDVDMLRRENGQLLRERNLLQQSWEDMKRLHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAMDKLEVVKKDYDALRKR--YSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRDTAIQLQHQCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREERDAVYSEYKLIMSERDQVISELDKLQTEVELAESKLKSSTSE--KKAANEEMEALR-----------------------------------------------------------------------------QIKDTVTMDAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSIRTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLMAHSSHDSAIDTDSMEWETEVVEFERETEDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADGRLRVNDWLLRINDVDLINKDKKQAIKALLNGEGAINMVVRRRKSLGGKVVTPLHINLSGQKDSGISLENGVYAAAVLPGSP----AAKEGSLAVGDRIVAINGIALDNKSLNECESLLRSCQDSLTLSLLKVFPQSSSWSGQNIFENIKDSDKMLSFRAHGPEVQAHNKRNLIQHNNSTQTDIFYTDRLEDRKEPGPPGGSSSFLHKPFPGGPLQVCPQACPSASERSLSSFRSDASGDRGFGLVDVRGRRPLLPFETEVGPCGVGEASLDKADSEGSNSGGTWPKAMLS---STAVPEKLSVYKKPKQRKSIFDPNTFKRPQTPPKIDYLLPGPGPAHSPQPSKR----AGPLTPPKPPRRSDSIKFQHRLETSSESEATLVGSSPSTSPPSALPPDVDPGEPMHASPPRKARVRIASSYYPEGDGDSSHLPAKKSCDEDLTSQKVDELGQKRRRPKSAPSFRPKLAPVVIPAQFLEEQKCVPASGELSPELQEWAPYSPGHSSRHSNPPLYPSRPSVGTVPRSLTPSTTVSSILRNPIYTVRSHRVGPCSSPPAARDAGPQGLHPSVQHQGRLSLDLSHRTCSDYS----EMRATHGSNSLPSSARLGSSSNLQFKAERIKIPSTPRYPRSVVGSERGSVSHSECS-----TPPQSPLNIDTLSSCS-QSQTSASTLPRIAVNPASLGERRKDR--------------------------PYVEEPRHVKVQKGSEPLGISIVSGEKGG-IYVSKVTVGSIAHQAGLEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNP------------------HVHQLSSHSRSSSHLDPAGT-HSTLQGSGTTTPEHPSVIDPLMEQ-----------------DEGPSTPPAKQSS--------SRIAGDANKKTLEPR-----------VVFIKKSQLELGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKTVEEVYVEMLKPRDGVRLKVQYRPEEFTKAKGLPGDSFYIRALYDRLADVEQ-ELSFKKDDILYVDDTLPQGTFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDNSATKTLSAAARRSFFRRKHKHKRSGSKDGKDLLALDAFSSDSIP----LFEDSVSLAYQRVQKVDCTALRPVLILGPLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNR-HCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDKVTQRHSKEQFEAAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPACPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T3B5-1", "uniprot_id": "A0AB32T3B5_DANRE", "id": "A0AB32T3B5-1", "name": "", "aln": "MEPKHKELLHQCHQNLLESITDADRLIELLSKSGSLSEQEAFELDQNCSSSAEKVEQLLKMLMNKQSDHFLELCVALEKTYPHLYSALFSN---GGGPADHHSGSTYSVLSTMPSDSESSS-SLSSVGTKASSP-PPALSDTRPASDSLDTILFQLKQVTRERDELRKRLALASPGTTFDDCRPNSKPGHDYERLKTQCTKAMADLQSLQNQHTKTLKRCEEAVKEADYYHIQHSRLLSEQTQLKEEMEVLKRENTKLTREHNHLKQSCEELRRLHSEDQREVADMRLQQQQVIRENGSSEVLNKLYDTAMDKLEGVKKEYDVLSKR--YSEKVSSHNTDLSRLEQVEEENRRLQKQIDALLKQRDTAIQYQQQWSTSMRRFDSVQQELNKASAQNKELQREMERLQSEVTRYKNFQLKAVKDGEKYKEERDSVFNEYRLIMSERDQVIKEVDKLQTELEAAEARLKNTSSE--RMVASEELEALRQELNSSLVDRDRAICERNELLEKYCHEVKDKAEAQKELSQACKDIETVREERDVARKERTEAIIQRDQLLREYYQARQKQDSATLDMERANKEIDILRKQCEAMSQELKEAVQEAEVAKCRRDWAFQERDKIVAERESIRTLCDNLRRERDRAVSDLADALRNLDDMRKQRNDAARELKELKEKMESQLDKEARFCQLMAHSSHDSAIDTDSLEWETEVVEFEKDRDDMDLKAMGFDIAEGVNDPYLPGDCGIFVSRVDKGSIADGRLRVNDWLLKINDVDLTNKDRKQVIKAVLNGGGLINMVVRRRKSLGGRLVTSVHINLIGHKDAGIALEGGVFVAGIAPGSP----AAREGSLTIGDRLIAINGIALDNKSLSECEALLRGGRDSLALSLMKFFPQST--SGQNIFESLREAEKSN-GRIHLTDVHSRNSRN-LKHNSSTQTDIYSCDTAGERRK-TRSDAEESLFSERKVFPISTLHPNTLRPASELGPVRYSASAFQEVCYTRSESVG-----------PECVTLETTLEKK-----HSGGTWPKMVVGVAMTTDSPAQLSIYRSPKQRKSIFDADTFKRPDTPSKADY--------HGPQPLKA----DSAPTPPTPPTRSDSFKFKHKHQGSSTSESTIS--------------AMSISEPKQED-------RNGNLYFSEG----KVLSSRKSCEEDIGRMWAEEPEVKRPRPKSAPALRRRMTPQNIPLQSFQSYSNDGDSVEQR-EMLRSSPNRPHRHSVGFVPTSYNGTLPPNSAHRGLAPCSAVTAVMKNPVYMVRSHRVHTNNCPTVVSQINQQHTHPSPQHQGQLSLDLSQKRSTDYSESSRSSRASHGTNSLPSSARLGSSNNLQYRTERIKIPSTPRYPRSILGSDRGSLSHSECSSPSLITPPLSPLNLETSSFASSQSQGSISTLPRISVSPVPTEERRKDRSLYRNRSFLRIPLAARPKFCSLRSLRPYLEEPRNVMVHKGAEPLGISIVSGENGG-IFVSKVTGGSIAHQAGLEYGDQLLEYNGINLRNATEQQARLIIGQQCDTITIMAQYNP------------------HMYQLGNHSRSSSRLEPVST-QSTPQGSGTATPDNHSTIDTLSEQ-----------------DEGTLTPSSKQTTPTTSPNSFIRMPSESSKKVPEAR-----------LVTVRKTQVELGIQLCGGNLRGIFVERLEDDSPARGADAVVPGDMILEYGSVNMKNKTVEEAYLEMLKPAETVTLRVQHRLDEFNQVKGTPGDGFYIRALYDRVAETEL-DLSFKKDDILYVDDTLPNGNFGTWMAWQLDENAQKIQRGQIPSKFMMDQEFYRRHSMTELKDETGSSKTLSAAARRSFFRRKHKHKRSSSKDGKDVVALDAISTDSIP----FLDDCVSLAYQRVQKIDCTSPRPVLILGPLVDPVKDMLVKDSPGKFSRCVLEVMKASQQAIERGVKDFLFIDYKRRSGHFDVTTVASINEITDKDC-HCLLDIAPHAIERLHSVHIYPIVIFIRYKNAKQIKEQKDPIYLRDKVSQKHSKEQFEIAQKIEQDYSKFFTGIVQGGTFPYICTQIVTIVDQEQSKVLWTPLGSP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKG8-1", "uniprot_id": "Q9VKG8_DROME", "id": "Q9VKG8-1", "name": "", "aln": "-----MAKMASGDLSLTSTSSQEEESSEYVGYDNTLRPPSNSSGSTTAAN------------MSNNNGPSKGVSSGVGVSG-----------------ISGGNGANYDILQAQYKSALLELNTLRHQHANTKRRCDELATELTLYQEHYVADRNKFTDMVEESARFKRLLLETQNQQSQQAQNGNSQVPPVGSGNPYYFGKTQGCDGSCSEKLAELKKERNMVAVEREKYKKSYIELEKDRNYYRERGDENQKLKVLLSQESKNVLSLTEELNQLLSEKDNVLQEHQKMSDDLVLANKEIERLKKDEQLARAEIKVLQLANADLKKRDLLKSRDSSWSKEFPSGKELEN-SKELEKLRKSLEKALSEVERSSQDAEEAKRVRDWAISQREKIVQERDSVKTLCDKMRHERDKAISDSLMAIRDSEKIKKQKDEAQKKIDLLKEQME--QQERQNLDSNASGSRRSFRPSSYEGEDLLEVELSG-----------------------------------------------------------------------------------YEHTSDLGIILDDSNKRKLVCGVTSSSPACGKLKINDVICKVNNLDCQSLSKRMVLDEIRACAPRSLLLVSRTRHSKRHAYSVQLKTRDRDCPHGLQLDMGVFIAKIEQNSLAFYEPELDVGDRVLSINNKSMDSVQSIEEVMQLMNDPRSDGLNLFALKYVQDQLPP---GMTTSSAQTDSIDS-----------MQHVSSAGGGGGSGPSSATKHPSRFAEFFFRKLKFS--KPGTPEDNFEQEHDDAIAALDSVLSENSSEKSKENLFNRKKRTKKEKEASKSMGTWPRTNISHENPTGTMRGNEKKRALMSLFTAGPINVDKDDELMGEVGVPEKQPAALIQDQLPPPLPPQMSKPLAHIRGSNGGAIKTHPNRNSNPVSSGVSALFP---PGPPNGMPNTSYPTHPRHSLYGVTAEEINQKPIQRAPLMG------------ANARVKMPSQERYGTRPHSNHRLSLNITP----SGDFYQPKTSGQQAQQQVMNASSTSAGFGVGSGSMVGGTGPAAGEFPVRKQQVYDVFHPPPLPKNSSGSNMFMPLHPTRGSHPPPVGQPPDVVSLKSQNSIESILSAKSPAISEYGMYAKRHVPQAVRHVP----KYPSDSESIGSGVHGGYGGFLQSNHMPGNRHTQLFPTFGPGGRGNRRSSPLTLPSPPPQQQLQQLPAATAPHDSVGIPTDLDYHPHHHTQTNAMPHPHPHPHAPYLDYGHGLGIGPYMGVGGGVSGVGGAIYEGGTFPRKKDNQRLRIPSNPSVASKSSSMVKNSSGSIDHHYVTSTGPVSGGSMSASSSDRAPMSLMSSSIHNSYGANIAGGNGTGSS------IGVGGGGGGGSGRGSPMPQVHVEVLSHGGGGSGKRNSNVPAD-------------------------FLCPGDLRRVTIDKRDKSLGITIQCNNNGGGIFVSTVADKSTAMRAGLQVGDQLLEVCGINMRAATQEIAANVLRQCGDSFTMLVQYNPEKFPSIEYEGAHNLEPESPINHSGSPTPRNSPRPPARNSLFPLPMQPQAPSTRPGSRAPLSHQSIKDQSFTDSLENQSDISSSQDMPSSAATTTTTTASATSTVYDEEPKPSLPPPPASVPAETLRYVTLHMDKSKNLGIKLFGGNKVGIYVHDVAVGSPSD-HAGIRKGDQILEYNGVDLSGVTAEQAANEISKLTDTVTMLVQNKLHTLKQIKDEPGDSFYIRVGFDRTGELNEDDLRFVKDEVLYVDNTVFNGTFGLWRAWKLDAMGHRKECGIIPSQMKVEEELR---SGEVVDCDTGTARRGSTSARRSFFRRK-KNQRSSSRDSTEIASFSNTQLSFFPDLGLLNDDGGALSYQRVELLDSPIRRPVLIIGPLSECLMVRLTIDFSNLFKLCEVTAMDCSQEAMEEGLKENIFVDYRRRGNKFECTTVEAISNACKNDRRHCILDVSISAVERLQRLQIYPIVLLLRFKSAKQIRDIRD--FGTDKISAKAAKEMYERAMKLETDYKQYISAVIPGVSIKHMCTQIKDAVDKEQDKLLWVPVSSG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . .* .: :: : : .:* . . . .. : :: . : .: : *:.*.:*. ..: . :* :. . .: :: :..* .::: * : : : . : . :: . * .:: :: *. : .. * : *: : .* .::. :: : :: : * :* : : . *::.:* .*.:. : : : .:::: * . * *:* : * ::: :: * ** ..: : . ::. ::: : .:.* * . * : . . : .:: : * : : .* :...:: : :: * . . .: : ::.** ::::* . .: *: .: : .* ::*::: . :. :: :: * * * * .: : : * . ... . : : . *: : : . :.**: . . .*: . .* . *.: . :*. : : :. * : : ..: :*:..*:: .: *. : :* ..:.: : *:: * *: .: .:..** . ::.*. . . . .: : . : .. *: .:. . . *: .:* .*: ..* * :: : : ::. . * * .: . :*. ... :* : . ..:::: .: .:: : . : :: . :*.. ... .: : : . .. . :. : . . :: :*. . : : : . . *:: : ..* . . . * : . . *. . *: : * . * . :. .* . : . . . :. ..: :: : . : : * : . : : :. . : . .. * . . : . : .: . . . . :.: :* : . .:. * . .: . : :.*:. :.... ::* :. . :. *:: .. . : .* . . . * .* ..*.: . .. .. : *.* :.* :.***:* ..::** ::**.*: * * :***: ****** ***:* **:: * :: * *::*::.**** : : .. : .* *. . . .. . . .* .* ... *.: :: .: * . :. ... :**::* *** *::* : .**: .: ** ****..::: . * *:. *: * : : : ** : . :.: *. .**.****. :** .: : :* * **::****:*: :* ** * **:** .:: : * ***: :::*: * :. :. ::: *::********* *::**.*:*..:: ::. . . :* : :* :*:****: :*.. ****::*** : : *. : .. * * : .*..**:*:*.*:*: :*:**:**..:*: *** :*.: .:: **:**:: *:***: ::*****:::::*.**:*:: :* : **:: : :** :* * *:: :*.::::.:: * :: :**** *.:**.*:** * . ", "identical_positions": 277, "similar_positions": 655, "identity": "13.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3151", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q12906-1", "uniprot_id": "ILF3_HUMAN", "id": "Q12906-1", "name": "Interleukin enhancer-binding factor 3", "aln": "-----------------------------------------------------------------------------------------------MR--PMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQAESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTALLDKVADNLA--IQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEATDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIPPSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELN-EKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGG-YMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYS-YSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGG-ASYNPGSHGGYGGGSGGGSSYQGKQGGYS-QSNYNSPGSG-QNYSGPPSSYQSSQGGYGRNADHSMNYQYR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z1X4-1", "uniprot_id": "ILF3_MOUSE", "id": "Q9Z1X4-1", "name": "Interleukin enhancer-binding factor 3", "aln": "-----------------------------------------------------------------------------------------------MR--PMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGNSELSEAENMDTPPDDESKEGAGEQKAEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTALLDKVADNLA--IQLTTVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEATDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIPPSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKADPPQAMNALMRLNQLKPGLQYKLISQTGPVHAPIFTMSVEVDGSNFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEESDGKPAIVAPPPVVEAVSNPSSVFPSDATTEQGPILTKHGKNPVMELN-EKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALEANKKKRTPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNIRGRGRGGNIRGRGRGRGFGGANHGGGYMNAGAGYGSYGYSSNSATAGYSQFYSNGGHSGNAGGGGSGGGGGSSSYSSYYQGDSYNSPVPPKHAGKKPLHGGQQKASYSSGYQSHQGQQQPYNQSQYSSYGTPQGKQKGYGHGQGSYSSYSNSYNSPGGGGGSDYSYDSKFNYSGSGGRSGGNSYGSSGSSSYNTGSHGGYGTGSGGSSSYQGKQGGYSSQSNYSSPGSS-QSYSGPASSYQSSQGGYSRNTEHSMNYQYR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QZW7-1", "uniprot_id": "F1QZW7_DANRE", "id": "F1QZW7-1", "name": "", "aln": "MAQMRHFPRRRDGPLPPRPPPAWDEHLAYEELLHWDNLMQEGYHLHPHDYERYEELRYWYDCLCYEEDLRQYNDYIVEYRKWEEENLHPEEPMPPMRPPPQRTFVNEDRYLRAKHTTVYPSSEQLDAVQNMVSHIEFAMKAVSDWFNEKEAG--------------DTDTKSKSSQSK-------LRGVLRVGLVAKGLLLKDDLDLELVLLTRDAPTSSLLRLVSGKLS--ELIKDVTEEKYVITPSIQEASVIVTSTKEPLLKLRIHLTSPVVREQVEKEASGEPCAESSPQDALDRQKCLASLASLRQAKWFQAKVSGLESCVIVIRILRDLCSRVSTWAPLKGWTLELLCQKAISTSERMLGPGEAFRRVLECLASGIIMEGGPGISDPCERDTTDAAVYLTSQQREDITQSAQFALRLSAFGQLYKVLGMDRLTSKAAR------MIEHRVPDP--------PIKRPRE--SFDGGDFDTRLKFPRKEERKEPP---NALMKLNQLRPGTVYKLASQTGPEHEPQFSMTVEVDGVTYEATGPSKRSAKLHVAQKVLVALGVPLPSETKP-------AEEKKSQ-SVSTPAATASSENTPT---GSDDGAEGGPILTKHGKNPVMELN-EKRRSLKYELVSVKGRFNDKTFTIEVDVDGQKFQGSGSNKKLAKANAALAALEQLFPNCP-----------PEPVK-----KKKFNPMGYGMGGVSFN--------RGRGRG-----RGRGRGFN-----------------------------TTKFTDPSTSVNPQADPS---AASTASAATYQ------AVPPPVTG-----------YYN-----------QYTQS-YSQFKKPQDQAQNENQNQ------SKTANQQAPLVGPDYGYG----YQGAG-------MNMAAPPNYN---YAAYSGPPGTAS--------------FGPPGTTNQSYNFTQSAYPN-LGGYSSGGASTTDYTYR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86BI3-1", "uniprot_id": "Q86BI3_DROME", "id": "Q86BI3-1", "name": "", "aln": "-----------------------MANNNYAGFNYGGTQYNTGQVSYPAVTNATYANAAAYQNAAVAAGQGGYGG--AAGAGAGATSGPGAGGYGGYGDYRSAMQYDATKTFYQQSPASYNASGSTASVSKTHYSAPPVKNQVKGKMDKSNGG-------------PKPPSSAPPAGNN-------YSGYDTALYNAASMYVAQQHQGNPNQKPNGGANNWYQRKMGATIPGATAIRGMRPKAPPRPQQLHYCEVCKISCAGP-QTYREHLEG-QKHKKREASLKMSASANSATQNRGNNYHCELCDVTCTGTDAYAAHVRGAK-HQKVVKLHQKLGKPIPSEEPKKMGKINFVPAAAGGAGVAKTEGGANESDAAGDLDDNLDDSLG-ENTDNIKPVGGEYIEEVKDEEGKILSFNCKLCDCKFNDPNAKEMHMKGRRHRLQYKRKVQPDLVVDFKPTPRQRRLAEARANRAMMSSHRGGDDHDGGYWEEQRNRQYNEEYDYNNWMSR-SFGGAQRFGRMGNGPPPHFGMMPGGNVRRPESTDDRHAIARHAEIYPKEEELQTIQRIVSHTERALK---LVSDALAEQPSDAGAANKKDKAEKPSEKDGRDNQIFSFQKDADNGGNVVRILKGVMRVGYLAKGLLLHGDNAVELVVLCAEKPTSGLLQRVANVLPDKLKEVAGDTQVNYRVEVNAEEAALIVLDESVSVKITLTSPLLRDANPGEAATTDE---------GEGDSEFLPREPCLRALADLR-------------------------HAKWFQARATGLQSCVMVIRILRDLCQRVSSWQS-------LPQWSLELLVEKVISSAGFP---ISPGDCMRRIMEALSSGFLINGPGLLDPCEKDPTDALLELTKQEREDLTVSAQLFLRYIAFRQIYKVLGMEPLPAMKFPMRPWRVNRKRRRSSGKAG---------------GAPGTETESNDIDETGSDEKVAKKEGVGGTPAST---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : .: * :. . :*.: . : *.. :::.: * . :. .. .: * . * .: : : : : . ... :. .:. : : . .:. . : . * . ** . ::: * .. : . . : :. :* . .: :. : *:. * : *::: :.* . :.: * : :::: : .:. * . * ..: * * : : : :: : :: ..: . : :: . : : * :*. . . :::.: : * * .: . : .: * * :. . : . : *::: : * : : :: : : .. . ..*: * :.:* * * *: * . : : * : ..: .: . : :* * . . : : . . * .. : *.* . . *.: : : . . :. : :* * : : :: * : . . : . : :. . : : . .* .. ..**: :. . :. . . . . ", "identical_positions": 48, "similar_positions": 223, "identity": "4.8%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3161", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35604-1", "uniprot_id": "NPC1_MOUSE", "id": "O35604-1", "name": "NPC intracellular cholesterol transporter 1", "aln": "---MGAHHPALGLLLLLLCPAQVFSQSCVWYGECG--IATGDKRYNCKYSGPPKPLPKDGYDLVQELCPGLFFDNVSLCCDIQQLQTLKSNLQLPLQFLSRCPSCFYNLMTLFCELTCSPHQSQFLNVTATEDYFDPKTQENKTNVKELEYFVGQSFANAMYNACRDVEAPSSNEKALGLLCGRDARACNATNWIEYMFNKDNGQAPFTIIPVFSDLSILGMEPMRNATKGCNESVDEVTGPCSCQDCSIVCGPKPQPPPPPMPWRIWGLDAMYVIMWVTYVAFLFVFFGALLAVWCHRRRYFVSEYTP-IDSNIAFSVNSSDK---GEASCCDPLGAAFDDCLRRMFTKWGAFCVRNPTCIIFFSLAFITVCSSGLVFVQVTTNPVELWSAPHSQARLEKEYFDKHFGPFFRTEQLIIQAPNTSVHIYEPYPAGADVPFGPPLNKEILHQVLDLQIAIESITASYNNETVTLQDICVAPLSPYNKNCTIMSVLNYFQNSHAVLDSQVGDDFYIYADYHTHFLYCVRAPASLNDTSLLHGPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTERLQRAWAWEKEFISFVKNYKNPNLTISFTAERSIEDELNRESNSDVFTVIISYVVMFLYISLALGHIQSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYMGMPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFGALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNHLDILCCVRGADDGQGSHASESYLFRFFKNYFAPLLLKDWLRPIVVAVFVGVLSFSVAVVNKVDIGLDQSLSMPNDSYVIDYFKSLAQYLHSGPPVYFVLEEGYNYSSRKGQNMVCGGMGCDNDSLVQQIFNAAELDTYTRVGFAPSSWIDDYFDWVSPQSSCCRLYNVTHQFCNASVMDPTCVRCRPLTPEGKQRPQGKEFMKFLPMFLSDNPNPKCGKGGHAAYGSAVNIVG-DDTYIGATYFMTYHTILKTSADYTDAMKKARLIASNITETMRSKGSDYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGSIFLVTLVVLGCELWSAVIMCITIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTMSTKGSRVSRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFEIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVNKAKRHTTYERYRGTERERLLNF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15118-1", "uniprot_id": "NPC1_HUMAN", "id": "O15118-1", "name": "NPC intracellular cholesterol transporter 1", "aln": "---MTARGLALGLLLLLLCPAQVFSQSCVWYGECG--IAYGDKRYNCEYSGPPKPLPKDGYDLVQELCPGFFFGNVSLCCDVRQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATEDYVDPVTNQTKTNVKELQYYVGQSFANAMYNACRDVEAPSSNDKALGLLCGKDADACNATNWIEYMFNKDNGQAPFTITPVFSDFPVHGMEPMNNATKGCDESVDEVTAPCSCQDCSIVCGPKPQPPPPPAPWTILGLDAMYVIMWITYMAFLLVFFGAFFAVWCYRKRYFVSEYTP-IDSNIAFSVNASDK---GEASCCDPVSAAFEGCLRRLFTRWGSFCVRNPGCVIFFSLVFITACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKHIYQPYPSGADVPFGPPLDIQILHQVLDLQIAIENITASYDNETVTLQDICLAPLSPYNTNCTILSVLNYFQNSHSVLDHKKGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTEKLQRAQAWEKEFINFVKNYKNPNLTISFTAERSIEDELNRESDSDVFTVVISYAIMFLYISLALGHMKSCRRLLVDSKVSLGIAGILIVLSSVACSLGVFSYIGLPLTLIVIEVIPFLVLAVGVDNIFILVQAYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLGALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCVRGAEDGTSVQASESCLFRFFKNSYSPLLLKDWMRPIVIAIFVGVLSFSIAVLNKVDIGLDQSLSMPDDSYMVDYFKSISQYLHAGPPVYFVLEEGHDYTSSKGQNMVCGGMGCNNDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRVDNITDQFCNASVVDPACVRCRPLTPEGKQRPQGGDFMRFLPMFLSDNPNPKCGKGGHAAYSSAVNILLGHGTRVGATYFMTYHTVLQTSADFIDALKKARLIASNVTETMGINGSAYRVFPYSVFYVFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCELWSAVIMCATIAMVLVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRVERAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVNKAKSCATEERYKGTERERLLNF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q2J0-1", "uniprot_id": "A0A2R8Q2J0_DANRE", "id": "A0A2R8Q2J0-1", "name": "", "aln": "MLLLGRNHIFRLLLATVLLSHWVHGQHCIWYGECGNSPNVPEKKLNCNYTGPAVPLPNEGQELLQELCPRLVYADNRVCCDTQQLNTLKSNIQIPLQYLSRCPACFFNFMTLFCELTCSPRQSQFISVK------DFLKEKNQTSVGNVTYYITQTFADAMFNACRDVQAPSSNIKALGLLCGRDASVCTPQIWIQYMFSISNGQVPFGIEPIFTDVPVQGMTPMNNRTFNCSQSLDDGSEPCSCQDCSEVCGPTPVPPPIPPPWIILGLDAMSFIMWCSYIAFLLIFFGVVLGAWCYRRSVVTSEYGPILDSNQPHSLNSDGTDLIDEASCCETVGERFENSLRLVFSRWGSLCVRQPLTIILSSLVLICICSAGLSYMRITTNPVELWSAPSSRARQEKNYFDQHFGPFFRTEQLIITTPWTEEGGFS-TITGDIIPFSPILNLSLLHQVLDLQLEIENLIAEYKGENVTLKDICVSPLSPYNDNCTILSVLNYFQNSHEVLDHEFQDEFFLYNDYHTHLLYCASSPTSLDDTSRLHDPCMGTFGGPVFPWLVLGGYEDSAYNNATALVITFPVTNYLNDTEKLGKALAWEKEFIRFMKNYENPNLTVSFSSERSIEDEIDRESNSDVSTIVISYIIMFVYISVALGRINSCRTLLVDSKISLGIAGILIVLSSVACSLGIFSYIGIPLTLIVIEVIPFLVLAVGVDNIFIIVQTYQRDERMPEEELHQQIGRILGDVAPSMFLSSFSETVAFFLGALSTMPAVRTFSLFAGLAIFIDFLLQISCFVSLLGLDIKRQEANRMDILCCVKLS-DGQE-EKSEGWLFRFFKKIYAPFILKDWVRPLVVAVFVGMLSFSIAVVNKVEIGLEQTLSMPDDSYVLNYFGNLSKYLHTGPPVYFVVEDGHDYKTFEGQNAVCGGVGCNNDSLVQQIYTASLMSNYTRISNVPSSWLDDYFDWVKPQSTCCRYYNSTGAFCNASVVDKSCVHCRPMTSSGKQRPNGTEFMHFLPMFLSDNPNIKCGKGGHAAYGTAVDLKD-NNTDVGATYFMSYHTILKNSSDFINAMKMARELTDNITQTLSTHDKSYKVFPYSVFYVFYEQYLTIVDDTALNLGVSLSAIFIVTAVLLGFELWSAVLVCFTIAMILINMFGVMWLWSISLNAVSLVNLVMSCGISVEFCSHIVRAFSISTRSSRVERAEEALAHMGSSVFSGITLTKFGGILILALSKSQIFQIFYFRMYLAIVLLGAAHGLIFLPVLLSYAGKSLSPRTFMICLEAVVHLKHLKTRHH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ** :* . *..* *:****** :*: **:*:**. ***::* :*:***** :.: : :*** :**:***.*:*:***:*****:**:*::.*********:****:.*. * .::.:*.* :: *:: *:**:**:******:***** ********:** .*.. **:***. .***.** * *:*:*..: ** **.* * .*.:*:*: : ******** ****.* *** * ** * ***** .*** :*:***::***..:..**:*: ..*** * :*** ..*:*:... .*****:.:. *:..** :*::**::***:* :*: **.:* **:** ::::*****:***** *:** **:***:************* :* *. :. :* :**.* *: .:********: **.: *.*..*.***:***::****** ****:********** *** : *:*::* *****:***. :*:**:*** **.**:****************:*. *************.** ****:* :* ******* *:***:*****:**::*******::***:*** *::*** :**:***:***:::** ******:*******************:***:*:************************:**:******: * *.**:**:**:***:********* ***:**** ****:*******:*::*******:************** *::**:***: : ** . **. ******: ::*::****:**:*:*:***:****:**:***:***:*:****:***:::** .:::***:*******:*:*::*.: :*** ****:**:********:.*: :..***:. .****:*******.***:*** * * ******:* :**:***:*..*****:* :**:*********** **********.:**:: ..* :******:***:*:.*:*: :*:* ** ::.*:*:*: :.. *:*****************:*** :**.***.:**:** *:** ******::* ****:*:*********.*************************.***::* :.***.*************************::**::*****:*********:*****:************ * *:. . * :: : :.", "identical_positions": 806, "similar_positions": 310, "identity": "62.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3165", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q02809-1", "uniprot_id": "PLOD1_HUMAN", "id": "Q02809-1", "name": "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "aln": "MR---PLLLLALLGWLLLAEAKGDAKPEDNLLVLTVATKETEGFRRFKRSAQFFNYKIQALGLGEDWNVEKG-TSAGGGQKVRLLKKALEKHADKEDLVILFADSYDVLFASGPRELLKKFRQARSQVVFSAEELIYPDRRLETKYPVVSDGKRFLGSGGFIGYAPNLSKLVAEWEGQDSDSDQLFYTKIFLDPEKREQINITLDHRCRIFQNLDGALDEVVLKFEMGHVRARNLAYDTLPVLIHGNGPTKLQLNYLGNYIPRFWTFETGCTVCDEGLRSLKGIGDEALPTVLVGVFIEQPTPFVSLFFQRLLRLHYPQKHMRLFIHNHEQHHKAQVEEFLAQHGSEYQSVKLVGPEVRMANADARNMGADLCRQDRSCTYYFSVDADVALTEPNSLRLLIQQNKNVIAPLMTRHGRLWSNFWGALSADGYYARSEDYVDIVQGRRVGVWNVPYISNIYLIKGSALRGELQSSDLFHHSKLDPDMAFCANIRQQDVFMFLTNRHTLGHLLSLDSYRTTHLHNDLWEVFSNPEDWKEKYIHQNYTKALAGKLVETPCPDVYWFPIFTEVACDELVEEMEHFGQWSLGNNKDNRIQGGYENVPTIDIHMNQIGFEREWHKFLLEYIAPMTEKLYPGYYTRAQFDLAFVVRYKPDEQPSLMPHHDASTFTINIALNRVGVDYEGGGCRFLRYNCSIRAPRKGWTLMHPGRLTHYHEGLPTTRGTRYIAVSFVDP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R0E2-1", "uniprot_id": "PLOD1_MOUSE", "id": "Q9R0E2-1", "name": "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "aln": "MR---SLLLLAPLAWLLLVQAKDDAKLEDNLLVLTVATKETEGFRRFKRSAQFFNYKIQSLGLGEDWSVDGGPAAAGGGQKVRLLKKALEKHADKEDLVILFVDSYDVVFASGPRELLKKFQQAKSQVVFSAEEHIYPDRRLEAKYPTVPDGKRFLGSGGFIGYAPSLSKLVAEWEGQDSDSDQLFYTKIFLNPEKREQINISLDHRCRIFQNLDGALDEVVLKFEMGHVRARNLAYDTLPVVVHGNGPTKLQLNYLGNYIPRFWTFETGCTVCDEGLRSLKGIGDEALPTVLVGVFIEQPTPFLSLFFLRLLRLRYPQKQMRLFIHNQERHHKLQVEQFLAEHGSEYQSVKLVGPEVRMANADARNMGADLCRQDQTCTYYFSVDADVALTEPNSLRLLIEQNKNVIAPLMTRHGRLWSNFWGGLSADGYYARSEDYVDIVQGRRVGVWNVPYISNIYLIKGSALRAELQNVDLFHYSKLDSDMSFCANVRQQEVFMFLTNRHTFGHLLSLDNYQTTHLHNDLWEVFSNPEDWKEKYIHENYTKALAGKLVETPCPDVYWFPIFTEAACDELVEEMEHYGQWSLGDNKDNRIQGGYENVPTIDIHMNQITFEREWHKFLVEYIAPMTEKLYPGYYTRAQFDLAFVVRYKPDEQPSLMPHHDASTFTVNIALNRVGEDYEGGGCRFLRYNCSVRAPRKGWALLHPGRLTHYHEGLPTTKGTRYIAVSFVDP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8WIN7-1", "uniprot_id": "A8WIN7_DANRE", "id": "A8WIN7-1", "name": "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "aln": "MRGVLAFLACLFASFPPLHCNQQGSIPEGDLLVLTVATQETDGFRRFLRSAKHFNYTIKVLGRGETWRGGDYMTAPGGGQKVRLLKSALEDIQE-EKKVILFVDSYDVIFSSGPKELLKKFQQAKHKVVFSAETLIWPDRHLEDKHPHVREGKRFLGAGGFIGYAANLKKMLSDWSGADGDSDQLFYTKIYINKEKRKSINITLDSKCRLFQNLHGALDEVVLKFEDGRVRARNVLYDTLPVIIHGNGPTKLQINYLGNYIPNLWTFETGCTMCNQDRRLLSGLQESEYPVVVIGIFIQQPTPFVTVFFERLFNLKYPKNRLKLFIYNQETHHEQHIHAFLDSHESEYQGVKLIGPEEDIDPVSSRNLGFDMCREDIDCEYFFSIDVDVVLKNEDTLRILIEHNKPFIAPMLTKPGRLWTNFWGALSADGFYARSEDYVDIVQGHRVGLWNVPYVSHIFLIKADTLRTDLKDPDLFKSTTLDPDMAFCEKIRNKGVFMFVTNMDTFGRVLSTDNYQTNHLHNDLWQIFENPVEWEERYIHPNYSRVLKDEFIETPCPDVYWFPIFSEVACDHLVEEMENFGQWSGGANVDNRIQGGYENVPTIDIHMNQVGYEKEWQKFLLDYIAPVTEKMFPGYYTRAQFDLAFVVRYKPDEQPSLRPHHDASTFTINIALNHVGIDFQGGGCRFLRYDCSIRSPRKGWAFMHPGRLTHYHEGLPTTEGVRYIAVSFVDP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .:* .: * : .: *.:********:**:***** ***:.***.*: ** ** * ::.**********.***. : *. ****.*****:*:***:******:**: :****** *:***:** *:* * :******:*******..*.*::::*.* *.**********::: ***:.***:** :**:****.*********** *:*****: ******::*********:********.:********:*::. * *.*: :. *.*::*:**:*****:::** **:.*:**:::::***:*:* **: ::. ** .* ****.***:*** : ..:**:* *:**:* * *:**:*.**.*.: ::**:**::** .***::*: ****:****.*****:*************:***:*****:*:*:***..:** :*:. ***: :.**.**:** ::*:: ****:** .*:*::** *.*:*.*******::*.** :*:*:*** **::.* .:::*************:*.***.******::**** * * ********************: :*:**:***::****:***::************************* *********:*****:** *::*********:**:*:*****:::***************.*.**********", "identical_positions": 468, "similar_positions": 184, "identity": "64.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3167", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A729-1", "uniprot_id": "D4A729_RAT", "id": "D4A729-1", "name": "Cyanocobalamin reductase / alkylcobalamin dealkylase", "aln": "---MEPRVAELKQKIEGTLCPFGFEVYPFQVAWYNELLPPAFHLPFPGPTLAFVVLSTPAMFDRALKPFLKSCHLQTLRDPVDQCVSYHLKS-VTEKFPELHIEVIADYEVHPNRRPKILAQTAAHVAGAAYYYQRQDVDADPWGTQHIAGVCIHPRFGGWFAIRGVMLLPGIEVPN-LLPRKPPDCVPTRAARITLLEGFNFHWRDWTYRDAVTPEERYSEEQKIYFSTPPAQRLALLGLAQPSGHPSTTS-EHPLSLLT--KPQDSRRLRSWLSPSVSPPASPGP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CZD0-1", "uniprot_id": "MMAC_MOUSE", "id": "Q9CZD0-1", "name": "Cyanocobalamin reductase / alkylcobalamin dealkylase", "aln": "---MEPRVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPFPGPTLAFLVLSTPAMFDRALKPFLKSCHFQTLRDPVDQCVSYHLRS-VTEKFPEVHMEVIADYEVHPNRRPKILAQTAAHVAGAAYYYQRQDVDADPWGTQHIAGVCIHPRFGGWFAIRGVMLLPGIEVPN-LPPRKPPDCVPTRAGRITLLEGFNFHWRDWTYRDAVTPEERYSEEQKIYFSTPPAQRLALLGLAQPSEHPSTTS-ELPLSLLT--KPQNSRRARSWLSPSVSPPVSPGP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y4U1-1", "uniprot_id": "MMAC_HUMAN", "id": "Q9Y4U1-1", "name": "Cyanocobalamin reductase / alkylcobalamin dealkylase", "aln": "---MEPKVAELKQKIEDTLCPFGFEVYPFQVAWYNELLPPAFHLPLPGPTLAFLVLSTPAMFDRALKPFLQSCHLRMLTDPVDQCVAYHLGR-VRESLPELQIEIIADYEVHPNRRPKILAQTAAHVAGAAYYYQRQDVEADPWGNQRISGVCIHPRFGGWFAIRGVVLLPGIEVPD-LPPRKPHDCVPTRADRIALLEGFNFHWRDWTYRDAVTPQERYSEEQKAYFSTPPAQRLALLGLAQPSEKPSSPSPDLPFTTPAPKKPGNPSRARSWLSPRVSPPASPGP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RFU5-1", "uniprot_id": "MMAC_DANRE", "id": "Q5RFU5-1", "name": "Cyanocobalamin reductase / alkylcobalamin dealkylase", "aln": "MAISSERVEELLRTFRESLKAKGFEIYPFKVGWYNAVLTAAHHLQYPADTLAVLVISTPAMFECAFLPFLQSQSCESLRDPIDQCTAHTLSACISLCFANQFVDVSYDYEMLPSRKPKFLAQTAAHVSGAAYYYQTSDIHNPPWGEKKMFGVCVHPQLGGWFAIRALLVFRDVQAGAGFQQRDPADCVCTQEERIRLLESFNLRWRDWSYRDIVPAEDRYSDQQKQYFITPPGQRRALL------------------------------RQWGYLTDTQS-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* ** :.:. :* . ***:***:*.*** :*..*.** *. ***.:*:******: *: ***:* . * **:***.:: * : :.: ::: ***: *.*:**:********:******* .*:. *** ::: ***:**::*******.:::: .::. : *.* *** *: ** ***.**::****:*** *..::***::** ** ***.** *** * .:*: * ", "identical_positions": 118, "similar_positions": 74, "identity": "41.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3178", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIQ3-1", "uniprot_id": "CXXC5_RAT", "id": "Q5XIQ3-1", "name": "CXXC-type zinc finger protein 5", "aln": "MSSLGGGSQDAGGSSSSSNTSS--SSGSGQKAGGTDKSATVAAT-APASVADDAPPPERRNKSGIISEPLNKSLRRSRPLSHYSSFGSSGG--AGSMMGGESADKA--AAAAASLLANGHDLAAAMAVDKSNPTSKHKSGAVASLLSKAERATELAAEGQLTLQQFAQSTEMLKRVVQEHLPLMSEAGAGLP-------DMEAVAGAEALNGQSDFPY--LGAFPINPGLFIMTPAGVFLAESALHMAGLAEYPMQGELASAISSGKKKRKRCGMCAPCRRRINCEQCSSCRNRKTGHQICKFRKCEELKKKPSAALEKVMLPSGAAFRWFQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F8WFL6-1", "uniprot_id": "F8WFL6_RAT", "id": "F8WFL6-1", "name": "CXXC-type zinc finger protein 5", "aln": "MSSLGGGSQDAGGSSSSSNTNS--SSGSGQKAGGTDKSATVAAR-APASVADDAPPPERRNKSGIISEPLNKSLRRSCPLSHYSS-GSSGG--AGSMMGGESADKA--AAAAASLLANGHDLAAARAVDKSNPTSKHKSGAVTSLLSKAERATELAAEGQLTLQQFAQSTEMLKRVVQEHLPLMSEAGAGLP-------DMEAVAGAEALNGQSDFPY--LGAFPINPGLFIMTPAGVFLAESALHMAGLAEYPMQGELASAISSGKKKRKRCGMCAPCRRRINCEQCSSCRNRKTGHQICKFRKCEELKKKPSAALEKVMLSSGAAFQWFH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WA4-1", "uniprot_id": "CXXC5_MOUSE", "id": "Q91WA4-1", "name": "CXXC-type zinc finger protein 5", "aln": "MSSLGGGSQDAGGSSSSSNTNS--SSGSGQKAGGTDKSTAVAATTAPTSVADDAPPPERRNKSGIISEPLNKSLRRSRPLSHYSSFGSSGG--GGSMMGVESADKA--AAAAASLLANGHDLAAAMAVDKSNPTSKHKSGAVASLLSKAERATELAAEGQLTLQQFAQSTEMLKRVVQEHLPLMSEAGAGLP-------DMEAVAGAEALNGQSDFPY--LGAFPINPGLFIMTPAGVFLAESALHMAGLAEYPMQGELASAISSGKKKRKRCGMCAPCRRRINCEQCSSCRNRKTGHQICKFRKCEELKKKPSAALEKVMLPSGAAFRWFQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7LFL8-1", "uniprot_id": "CXXC5_HUMAN", "id": "Q7LFL8-1", "name": "CXXC-type zinc finger protein 5", "aln": "MSSLGGGSQDAGGSSSSSTNGSGGSGSSGPKAGAADKSAVVAAA-APASVADDTPPPERRNKSGIISEPLNKSLRRSRPLSHYSSFGSSGGSGGGSMMGGESADKATAAAAAASLLANGHDLAAAMAVDKSNPTSKHKSGAVASLLSKAERATELAAEGQLTLQQFAQSTEMLKRVVQEHLPLMSEAGAGLP-------DMEAVAGAEALNGQSDFPY--LGAFPINPGLFIMTPAGVFLAESALHMAGLAEYPMQGELASAISSGKKKRKRCGMCAPCRRRINCEQCSSCRNRKTGHQICKFRKCEELKKKPSAALEKVMLPTGAAFRWFQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AX14-1", "uniprot_id": "A0A8M3AX14_DANRE", "id": "A0A8M3AX14-1", "name": "CXXC-type zinc finger protein 5", "aln": "MS----GGQPEGSRTPKAQDQD-----TDQDCG------------------EDSPVIERRNRSGIISEPLSKSLKRSRTLSQYTA----------------ACPQT-----ANGLKHNGQAKSHTAKPAQPAQQQPQQPSASALVPSKLDRTLEQVLEGQNGLLHFAQAAALLKRAGMEHMLLPGGMGVGVGGGEVGSVDLEGATVADTVGGHTDFPYGVGGGFPFNPGLFIMTPAGVFLADSALHMAGLTEYPVQSELASAISSGKKKRKRCGMCPPCRRRINCEQCSSCRNRKTGHQICKFRKCEELKKKPSAALEKVMLPTGAAFRWFQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *.* *. :..: . :. ..* :*:* ****:********.***:** .**:*:: :. :: * .* **: : : :. . ::..* : : ** :*: * . *** * :***:: :***. **: * . *.*: *:*..: *:::.*::**** *.**:***************:********:***:*.*******************.*********************************************.:****:**:", "identical_positions": 160, "similar_positions": 70, "identity": "48.19%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3187", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y697-1", "uniprot_id": "A0A8I5Y697_RAT", "id": "A0A8I5Y697-1", "name": "AP-1 complex subunit gamma", "aln": "-------------MALSASRPRRGEMTSLEPGSAAYLTEERMPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCR--NVAKLLYMHMLGYPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTS-NSYLRKKAALCAVHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRK---------------------LVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRILGRN--------DDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGVFLAAEKYAP----SKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNS-VEMHAYTVQRLYKAILGD-------YSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCT--VNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTN----------------------------GPSEIVQTN---------------GETEPAP------------------LETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPASAGGELLDLLGD--------------------------------------ITLTGAPAAAPTPASVPQITQPP-FLLDGLSSQPLFNDIAPGIPS-----------ITAYSKNGLKIEFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSVVPAFNTGTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22892-1", "uniprot_id": "AP1G1_MOUSE", "id": "P22892-1", "name": "AP-1 complex subunit gamma-1", "aln": "-----------------------------------------MPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCR--NVAKLLYMHMLGYPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTS-NSYLRKKAALCAVHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRK---------------------LVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRILGRN--------DDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAP----SKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNS-VEMHAYTVQRLYKAILGD-------YSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCT--VNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTN----------------------------GPSEIVQTN---------------GETEPAP------------------LETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPASAGGELLDLLGD--------------------------------------ITLTGAPAAAPTPASVPQISQPP-FLLDGLSSQPLFNDIAPGIPS-----------ITAYSKNGLKIEFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSVVPAFNTGTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43747-1", "uniprot_id": "AP1G1_HUMAN", "id": "O43747-1", "name": "AP-1 complex subunit gamma-1", "aln": "-----------------------------------------MPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCR--NVAKLLYMHMLGYPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTS-NSYLRKKAALCAVHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRK---------------------LVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRILGRN--------DDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAP----SKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNS-VEMHAYTVQRLYKAILGD-------YSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCT--VNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTN----------------------------GPTEIVQTN---------------GETEPAP------------------LETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPSSAGGELLDLLGD--------------------------------------INLTGAPAAAPAPASVPQISQPP-FLLDGLSSQPLFNDIAAGIPS-----------ITAYSKNGLKIEFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNTGTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TXY2-1", "uniprot_id": "A0AB32TXY2_DANRE", "id": "A0AB32TXY2-1", "name": "AP-1 complex subunit gamma", "aln": "-----------------------------------------MPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCR--NVAKLLYMHMLGYPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQYVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTS-NSYLRKKAALCAVHVIRKVPELMEMFLPATKNLLSEKNHGVLHTSVVLLTEMCERSPDMLSHFRK---------------------LVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRILGKG--------DDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCDPEFKADCASGIFLAAEKYAP----SKRWHIDTIMRVLTTAGSYVRDDSVPNLIQLITNS-VEMHAYTVQRLYKALLDD-------ISQQPLVQVASWCIGEYGDLLVSGQCEEEEPIQVSEDEVLDVLEGLLVSNLSAPVTRGYSLTAIMKLSTRFSS---VNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRPALLERMPIMEKSATN----------------------------GPAEIVQTN---------------GETDAPI------------------LDTKHPPNIPQPISQANDLLDLLGGNDVVPVIQTTAPTKPASAGGELLDLLGD--------------------------------------LSLTGGPAPTPAPS-VP-MSQPP-FLLDGLTSQPLFNDIGAGIPP-----------MTAYNKNGLKIEFTFERSNPNPNIAVITIHATNTTEVDMTEFVFQAAVPKTFQLQLLSPSSNVVPALNQGSVTQVIRVLNPQKQQLRMRIKLTYTHKGSPVQDLAEVNNFPPQSWQ-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KVR8-1", "uniprot_id": "Q7KVR8_DROME", "id": "Q7KVR8-1", "name": "AP-1 complex subunit gamma", "aln": "MYPYYEQDWSVLPPENNRRFNPAFNMATIRQAFTEAVERVRMPTPTRLRDLIRQIRAARTAAEERAVVNKECAYIRSTFREEDSVWRCR--NIAKLLYIHMLGYPAHFGQLECLKLTASTRFTDKRIGYLGAMLLLDERQDVHLLITNCLKNDLNSSTQFVVGLALCTLGAIASPEMARDLASEVERLMKSP-NTYIRKKATLCAFRVIRRVPELMEIFLPATRSLLSEKNHGILITGVTLITEMCENSSDTLMHFKKDSGNRE---------------IVPNLVRILKNLILGGYSPEHDVSGVSDPFLQVKILRLLRILGHN--------DPDASEAMNDILAQVATNTETSKNVGNTILYETVLSIMDIRSEGGLRVLAVNILGRFLLNSDKNIRYVALNTLLRTVHADTSAVQRHRTTILECLKDPDVSIRRRAMELSFALINAQNIRTMTKELLLFLEKADAEFKAQCSSGMILAAERYSP----TTRWHLDTQLSVLIAAGNYVRDDVVSSTIQLVSSSPVPEQTYITNRFWESLQVANH----CEDKQPLLQVAVWAIGEYGDLFMYGANEDE-FERPTESDLIAVYYKFLTSAQVSTTSKQYALVSLAKLSTRLQQC--VEEIQALITSFGSHLNVDLQQRGVEFTQLFGHYKHLRPPLLEKMPAMQISRISSQNGESGGGSFDDNSPDVIENGVEGGGGGGHSLIESNMNTLGDNTNILLDLLGSTDLSAGGAGDLVAATDLSNAVHKKNSRNANDVVAPVSNNQDLLDLLDLDLSAPSSTTTGAPAGGGGGGGIVALVGDNNQSSAANMNNMLGGLDLGGFGSGLDSSASIPTNGNDLASMLGGLGAPPAASPSLAASAPVGNLIDGHAG-SLLADLNPTAASNNVVVPPQGPRLTALDKDGLLVQLVSVRGS---DCMRIYMTTTNNSDNTLDQYLLQAAVQRSFQLQMLTPSGSVLPPG--GVITQEMRVVATSNATLRMRLRIQYVLDGQQQVEQTEVSGFPEQQPAPAAAE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12028-1", "uniprot_id": "AP1G1_YEAST", "id": "Q12028-1", "name": "AP-1 complex subunit gamma-1", "aln": "-------------------------------------------MGSSLRSFIKDVRGAKTLADERAIITKQSAKIRTKLRDDHLPHEKRRVNIQKLLYLYILGEKTHFGQVESINLIASDDFVDKRLGYLAATLLLDESEDLLTLLTNMLNNDLHHPNKYAVSLALTSLGFLSSPELARDLYPDVENIIKNSRDPFLLKKALQCAAKLIFKDVSLLEIFNIEDITKILSSHSICTHGVLLGVTKIIQSILLIGLNRKKDEDEDEDGIDYSNDILSPLSLLLRDFFIRLENMNSKNIEPGYDVQGICDPFLQCEIIYTLKLYFQVGELLNSNNVLDYKDNFCDLLTRIATNTDSTKNSGQAILYETVKTIFSLDLNQPLRVLGINILAKFLAGKDNNTKYVSLNTLLKVVPQEPTAVQRHRKFISHCLQDTDVSIRMRALELSFAILDDSNLVELVNELMKFLAKQDEDSKDLIIYTIDHLIDTFDTRVVKDESWKLDVFFNILKLVGSFINYEKINDILIIINNTSQLSDKSEFLRKMLTISLNGTSAEISEENIGWQLVLIWCIGEYGDLVLNEGNKNGADIINESSITDYLLTLQELYTATNLKIINYILTAALKLSVRFHDAKNIEKLRQLILSYTDSTDLSLQMKSNQYEIFFNQSISVKKIILETMPKFEKITEE----------------------------------QDN------------------------------------------GKALSKNLISNEPVDLLSDLLGEDSKAESKASTGDN--VKPIDILEEIFGE-----------------------------------------KNDIAQVPKNANKEESINHS-SAVEANSGVTLPLDAN-----------------KIYDSSSLNVYASLLSANSGLAHLDLYFQAKS----LISDLKTFCAVPKAQKLTLGQLYPSSTINAS-QICKQSLKISGSGK--LKLRVKLDFHLNGSSSITNEQFDHKFDETL------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.:*: :* *:* *:** :: *:.* **:.:*::. . * *: ****:::** :****:*.::* ** *.***:***.* ***** :*: *:** ::***: ..::. .*** :** :.*.*:.*** :**.::*.. :.:: *** ** ::* : .*:*:* . : ..: : :*:: : : :* :: ::. *:*: . .* :**.*:.***** .*: *:: : * .: : *:*:::****:::** *::****** :*:.: : ****.:***.:** ..*:* :**:*.:**:.* : .******. * .**:* ****: **:*****::: .*: : :**: ** . : : * : : : . *::*. : :* .*.::. : : . : ::..: . * :: .: * *.*******.: :: .. : * *.: ***.*: ::.:: :: : . ::.** :. :: :* : :: :** ** :: . : * : . . . : * ***. : . :: . : :.*: . . * : ::. :. .* * . ....* : .. : : :.. : : .** :: :* : . .* ::: . : *::*::: : .*. :.. : ", "identical_positions": 192, "similar_positions": 269, "identity": "18.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3188", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKE3-1", "uniprot_id": "SCAM5_RAT", "id": "Q9JKE3-1", "name": "Secretory carrier-associated membrane protein 5", "aln": "-----------------------------------------------------------------------------------------------------------------------MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHLSLTKRLYYLWMLNSVTLAVNLVGCLAWLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISIIQAVGIPGWGVCGWIATISFFG---TNIGSAVVMLIPTVMFTVVAVFSFIALSMVHKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSTTPNYTYSNEM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKD3-1", "uniprot_id": "SCAM5_MOUSE", "id": "Q9JKD3-1", "name": "Secretory carrier-associated membrane protein 5", "aln": "-----------------------------------------------------------------------------------------------------------------------MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHLSLTKRLYYLWMLNSVTLAVNLVGCLAWLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISIIQAVGIPGWGVCGWIATISFFG---TNIGSAVVMLIPTVMFTVVAVFSFIALSMVHKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYSNEM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TAC9-1", "uniprot_id": "SCAM5_HUMAN", "id": "Q8TAC9-1", "name": "Secretory carrier-associated membrane protein 5", "aln": "-----------------------------------------------------------------------------------------------------------------------MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVSMTKRLYYLWMLNSVTLAVNLVGCLAWLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISIIQAVGIPGWGVCGWIATISFFG---TNIGSAVVMLIPTVMFTVMAVFSFIALSMVHKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYSNEM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P0C7-1", "uniprot_id": "SCAM5_DANRE", "id": "Q6P0C7-1", "name": "Secretory carrier-associated membrane protein 5", "aln": "-----------------------------------------------------------------------------------------------------------------------MAE--NNFPPLPRFIPLKPCFYQDFN-EIPDQHRTMCKRLYYLWILNSATLAVNLIGCLAWMCGGGGATNFGMAILWLILFTPCSYVCWFRPIYKAFKSDSSFNFMAFFFVFMAQVVISIIQTVGIPGWGVCGWLATITFFS---TNIGSAVVMLIPTIMFTAVAVLSFIALTKVHNFYRGSGGSMSKAQEEWTSGAWKNPHVQQAAQQAAMGAAQGAMQG--QQYSAAPTYNYDDPM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXV6-1", "uniprot_id": "Q9VXV6_DROME", "id": "Q9VXV6-1", "name": "Secretory carrier-associated membrane protein", "aln": "MSGSGLDENPFGEPNLDNPFADPAIQQARRLQSGAALVSLEDYNPFEEQAKPQLQINSTNTAAVVQPLSQNIPPPQTSSLGASAPSTSIQITSEELQRRQEELDRKAAELDRREQQLQGNVPQLNNWPPLPDNFCVKPCFYQDFEVEIPPEFQKLVKRLYYIWIFYTMTLLANVIGGLILLFHAGEFETFFLAIFYTMLFSPASYVCWFRPAYKAFRNDSSFNFMVFFFIYFFQTLYSIVQAVGFNKMGYCGFITAIGQFDGQASGIIVGILLLNVAFCFTAVAVANVLMITKIHSIYRSTGASMAKAQAEFTTEFLRNQHVQEAASSAVNTAINSQFNN--SRY------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **:**** : :********: :** :. .: *****:*:: : ** .*::* * : .* .* :*::: :**:*.******** ****:.****.**.*** :: * : **:*:**: * **::::* *. :.* .:::* :. **.:** ..: :: :*.:**.:*.*::*** *:*: :* ***:**..*. * :. :: :* ", "identical_positions": 90, "similar_positions": 77, "identity": "25.21%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3189", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LQB4-1", "uniprot_id": "F1LQB4_RAT", "id": "F1LQB4-1", "name": "Palmitoyltransferase", "aln": "MSTLCSVIKFENLQDLRRLCHWGPIIALGVIAICSTMAMIDSVLWYWPLHTTGGSVNFIMLINWTVMILYNYFNAMFAGPGFVPRGWKPENPQDSMYLQYCKVCQAYKAPRSHHCRKCNRCVMKMDHHCPWINNCCGHQNHASFTLFLLLAPLGCTHAAFIFVMTMYTQLYNRLSFGWNTVKIDMSAARRDPPPIVPFGLAAFAATLFALGLALGTTIAVGMLFFIQIKIILRNKTSIESWIEEKAKDRIQYY--QLDEVFVFPYDMGSKWKNLKQVFTWSGVPEGDGLEWPIREGCHQYSLTIEQLKQKADKRVRSVRYKVVEDYNGACCPLN-RGVRTFFTSPCTEEPRIQLQKGELVLATRGLRYWLYGDKILDDSFIEG------TSRIRGWFPRNCVEKCPCDGES------------DPAPEGEKKNR-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CPV7-1", "uniprot_id": "ZDHC6_MOUSE", "id": "Q9CPV7-1", "name": "Palmitoyltransferase ZDHHC6", "aln": "MGIFCSVIKFENLQDLRRLCHWGPIIALGVIAICSTMAMIDSVLWYWPLHTTGGSVNFIMLINWTVMILYNYFNAMFAGPGFVPRGWKPEKSQDSMYLQYCKVCQAYKAPRSHHCRKCNRCVMKMDHHCPWINNCCGHQNHASFTLFLLLAPLGCTHAAFIFVMTMYTQLYNRLSFGWNTVKIDMSAARRDPPPIVPFGLAAFAATLFALGLALGTTIAVGMLFFIQIKIILRNKTSIESWIEEKAKDRIQYY--QLDEVFIFPYDMGSKWKNFKQVFTWSGVPEGDGLEWPIREGCDQYSLTIEQLKQKADKRVRSVRYKVIEDYNGACCPLN-RGVRTFFTSPCTEEPRIRLQKGEFILATRGLRYWLYGDKILDDSFIEG------TSRVRGWFPRNCVEKCPCDGDS------------DPAPEGEKKNR-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H6R6-1", "uniprot_id": "ZDHC6_HUMAN", "id": "Q9H6R6-1", "name": "Palmitoyltransferase ZDHHC6", "aln": "MGTFCSVIKFENLQELKRLCHWGPIIALGVIAICSTMAMIDSVLWYWPLHTTGGSVNFIMLINWTVMILYNYFNAMFVGPGFVPLGWKPEISQDTMYLQYCKVCQAYKAPRSHHCRKCNRCVMKMDHHCPWINNCCGYQNHASFTLFLLLAPLGCIHAAFIFVMTMYTQLYHRLSFGWNTVKIDMSAARRDPLPIVPFGLAAFATTLFALGLALGTTIAVGMLFFIQMKIILRNKTSIESWIEEKAKDRIQYY--QLDEVFVFPYDMGSRWRNFKQVFTWSGVPEGDGLEWPVREGCHQYSLTIEQLKQKADKRVRSVRYKVIEDYSGACCPLN-KGIKTFFTSPCTEEPRIQLQKGEFILATRGLRYWLYGDKILDDSFIEG------VSRIRGWFPRKCVEKCPCDAET------------DQAPEGEKKNR-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F6D7-1", "uniprot_id": "ZDHC6_DANRE", "id": "E7F6D7-1", "name": "Palmitoyltransferase ZDHHC6", "aln": "MNILSAIIVFENLHEVKRLFHWGPIIALTVIGVCSSMAILDSIIWYWPLDTTGGSINFIMLINWTVLILYNYFNAMFVGPGYIPLEWKPEKQQDIMYLQFCRLCQGYKAPRSHHCRKCNRCVMKMDHHCPWINNCCGHLNHAYFTSFLLLAPLGCIHAALIFIMTMYTQLYDRISFGWSSVKIDMSAARHIHHPIMPFSIAAFAATLFALGLALGTTIAVGMLFFIQMKVILRNRTSIEAWIEEKAKDRIQYY--QTGEDFIFPYDLGSRWENFKQVFTWSGAPMGDGIEWPVHEKCDQYTLTIEQLKQKHDKRQRSVEYRVVEEYNGACCPLG-KGLNTFFRTPCTEEPRIKLTKGETIFATRGTKWWMYGDKVLNEEQAKA------GVRIRGWFPRRCVEKCLYDSAN------------NSTSE-EKKEQ-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VG80-1", "uniprot_id": "Q9VG80_DROME", "id": "Q9VG80-1", "name": "Palmitoyltransferase", "aln": "-------MSPEISG-FRRFLHWGPITALSIIKCITLTTLYMNSMWWPPNKSFAGFAHQALFLLLSTLATFNYVMATLTGPGLMPKQWHPKDPKDAQFLQYCKKCEGYKAPRSHHCRKCDRCVKKMDHHCPWINHCVGWANHAYFTYFLLFSILGSLQGTVVLCCSFWRGIYRYYYLTHGLAHLAS----------VQFTLLSIIMCILGMGLAIGVVIGLSMLLFIQLKTIVNNQTGIEIWIVEKAIYRRYRN-ADCDDEFLYPYDLG-WRANLRLVFNDECQKRGDGIEWPVVEGCDQYTLTREQLAQKEEKRARTRTFKCTRPVTGRWLPIFSQGWRVCVAAPCSDEPRISLRPNDMIKVTRFRNHWLFGERVLSEQELAGVKKRQRKGPIRGWFPRRSAVEVIEAVHE----GSGDGNSETPAPAAQNGNAHSHLKQQQR-----NGHAKKYM---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VSV3-1", "uniprot_id": "Q9VSV3_DROME", "id": "Q9VSV3-1", "name": "Palmitoyltransferase", "aln": "-------MCIKLKDDLRRFIHWGPITLLTLTLIVTWTVIHMNSMWWAPGSSLESVLNYALIWIQTFGTLYNFIRSLMVGPGFVPLKWHPQLTKDKMFLQFCTRCNGYKAPRSHHCRRCNRCVMKMDHHCPWINTCVGWSNQDSFVYFLLFFMSGSIHGGIIIVSAVIRGIKKRWLIRYGLRHMAT----------VHLTQTNLLACVFSLGVIMGTVLASIKLLYMQMKSILKNQTEIENWIVKKAAFRRNAYPRKGIKPFVYPYNLG-WKTNMREVF----FSTGDGISWPVLPDCNEYSLTCEQLQQKKDKRARTRVFRCIRPATGHWVPIFSQGLWVSLQIPCTDDPRIALKPDDIIHVTRIQEYWLYGEIMISEKQKE--KIRARKGAIRGWFPSCCAIEICEDSDSENDLAGGEPVKEQDTAAIESVETDQEIIDFMRDFSCNDGKKAKRLHIE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .:*: ***** * : : .: . :*: * : . : :: : :*:. : :.*** :* *:*: :* :**:* *:.**********:*:*** ********** * * *: *. ***: *. :. .:: :. : : . :: : : : ::.:*: :*..:. *:::*:* *:.*:* ** ** :** * . . *::**::* *:: ** ***:.**: *.:*:** *** ** :** *: :: . .* *: :* . . **:::*** * .: : .** . *::*: ::.:. :***** .. : :. :. : ", "identical_positions": 110, "similar_positions": 120, "identity": "23.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3200", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZVH2-1", "uniprot_id": "A0A8I5ZVH2_RAT", "id": "A0A8I5ZVH2-1", "name": "", "aln": "MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPPPPPPPPPPPP-ASGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGGRRKQPPPPP-ASASSASGPGRGGRGGGGGRTGGGGG--HLARTTSARRAVNKVVYDDHESEDDDEEEDMVSEEDEEEEEDGDAEETQDSEDDEEDDMEEDDDDSDYPEEMED-DDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVVRNFGNVLRLSPFCFEDFCAALVSQEQCTLMAEMHVALLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHH-VLPYQEAEDYPYGPVESKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEVQKNKPYVRHEPIGYDRSRRKYWFLNRRLIIEEDTENENEKKVWYYSTKVQLAELIDCLDKDYWEAELCRVLEDIREEMQQHMDVTEDLTNKARGSNKSFLAAANEEILDSLRIKRGEDIDCDQ--NPEDTEKDKNEGENDSSKGAEKSREESEDQSPDKDADGKVLEEEPGQGKPEEPTEVGDKGNSVPANLGDNTRNASSEET-PCEGRSPEGWLSETHDSS-TAEKKVASELPPDVPEDSHK-TCDSSNTSATTASSQPNLENCSSSSSSSELTSSQSDSAKAADDPDIGERDSHTPVSVQEEIG-DFRLDKSNGEVSESPGTGKGTSGSTRIITRLRNPESKLSQLKSQQ-VAAAAHEANKLFKEGKEVLVVNSQGEVSRLSTKKEVVMKGNINNYFKLGQEGKYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLESNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQ---EEEETMQQATWVKYTFPVRHQVWKQKGEEYRVTGYGGWSWISKTHVYRFLPKLPGNTNVNYRKPLEGVKNNMDENKDESDKRKSPRSPKKMKTECDSEKGEARDADSTAGATAGTMELSKLPEKEEHDVKELLDPDNDKPFKEEPMEIDDSVKTESHMNSEESAQVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIRQFTLEEKQRLEKLKLESGVKGAGKPPTGAVKSSSEPPVSTKADEGHQGDLLRQEQRSTPSQAGTADLGLGASQSDPLVLGISPPSLSTGKPDPKGQVLDDVSIQSPGPACQGQNSVESDLDARISEATSKGLELSQTKTKVTDSLTDDSKPTSADEGSTLICKSKKPLPQDDCSTAVSSSSKSTLPAPVPKSPRDRDARAFPKAMDLDGRLGGDSEYNSTLENNSGTMYMRDSSEEDMVVQNSNDTTSKRFITPDQGMESTEPTKCQLVS-KSTENCDNRLQGKVTEANGKKLGQHQ-KPEERAVNRCADQVSLRHSADRKNSEARESEKRGQKANKFQINGKDSKAKGYLKGPGMKDVSDGKVMSGAVEPKVNNINKVIPGN-IKSLAGKESAVKPFVNGDIIMEEFSEQNTSETNSYSLSSSDAKGNHQDGLHTLPSTKDSASTQVIIPPAPCPDRNSLNQVEDMETE---GPEVKKVTPSPITTGEDSNLGKDVMDENGLPSSKDENVNGESQRKTVITEVTTMTSTVATESKTVIK-----VAKGDKQTVVSSTENCARSTVTTTTTTVTKLSTPSPDSDVDTVSVKEQSKTVVTTTVTDSLSTAGSTLVTSMTVSREYSTRDRVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPCFNYNAKPALDIWPYPSPRP-----TFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGSTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVVIESWVAEEELELWEIRAFAERVEKEKAQAVEQ--------------------------QTKKRLEQQKPAVIAASTTSPTNSTSSTVSPAQKVMVAPLSGSVTPGTKMVLATKVGSPATVTFQQNKNFHQTFATWVKQGQ----------------------------------------------------------SNSGVVQVQQKVLGIIPSTAGPSQQTFTSFQPRTATVTIRPNTSASAGTTTTSQVITGPQIRPGMTVIRAPLQQP-ALGKAVIRTPVTMQPGAPQQVVTQIIRGQPVSTAISASSTASSAPVQKGLTPGAAAGTLQPSAPHSPRPQQGQVKLTMAQLTQLTQG-HGGNQGLTVVIQGQGQTTGQLQLIPQGMTVLPGPGQQLMQAAMPNGTVQRFLFTPLSTPVTAVSSSS--SSSSTNATATGSGEQKQSKLSPQTQVQPATTLAPTQSSSVSPAEAQPQPAQPAAQPQPQPQPP--------AQPEVQTQPAASSHVPSETQPSQAQSSKPLVATQCQPQSSVQGQSPVRVQSPPLTRIRPSTPSQVTPGQQPQVQTTASQPIPIPPPTSLQAPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVPSPSRPQPQTQQPQPQVIAVPQLQQ-VQVLSQIQSQVVAQIQAQQ---GGAPQQIKLQLPVHVQQNS--AAQAQHAQSVLTVQAASVREQLQRVQQLRDQQQKKKQQ-IEMEREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKTMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNASKLSALLFKHKEQLKAEILKKRALLDKELQMQVQEELKRD-LKMKREREMAQVVQANAAAGPTPSVPAPVPAPAPAPAAPPAPP-SPPPSTHSLPPAGHPTAPLPVTSQKRKREEEKDS--KSKKKKMISTTSKEAKKDTRLYCICKTPYDESKFYIGCDLCTNWYHGDCVGITEKEAKKMDVYICNDCKRAQEGSSEELYCICRTPYDESQFYIGCDRCQNWFHGRCVGILQSEAELIDEYVCPQCQSTEDA-MTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERIQKRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A654-1", "uniprot_id": "A2A654_MOUSE", "id": "A2A654-1", "name": "", "aln": "MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPPPPPPPPPPPPPASGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGGRRKQPPPPPPASGSSASGPGRGGRGGGGGRTGGGGG--HLARTTPARRAVNKVVYDDHESDDDDEEEDMVSEEDEEEEEDGDAEETQDSEDEEEDDMEEDDDDSDYPEEMED-DDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVVRNFGNVLRLSPFCFEDFCAALVSQEQCTLMAEMHVALLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHH-VLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEVQKNKPYVRHEPIGYDRSRRKYWFLNRRLIIEEDTDNENEKKVWYYSTKVQLAELIDCLDKGYWEAELCRVLEDIREEMQQHMDVTEDLTNKARGSNKSFLAAANEEILDSLRIKRGEDIDCDQ--SPEDPEKDKHEGENNSSKDAEKSREEAEDPSADKDADSKGLEEEPGHGKPEEPTEVGDKGNSVPANLGDNTTNASPEETSPCDGRSPEGCLSETHDSSSMAEKKVASELPPDVPEDSNR-TCDSSNTSATTASSQPNLETCSSS----ELTSSQSDSAKAADDPEIGERDSHTPVSVHEEIG-DFRLEKSNGEVSESPGAGKGTSGSTRIITRLRNPESKLSQLKSQQ-VAAAAHEANKLFKEGKEVLVVNSQGEVSRLSTKKEVVMKGNINNYFKLGQEGKYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLESNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQ---EEEETMQQATWVKYTFPVKHQ----------VTGYGGWSWISKTHVYRFLPKLPGNTNVNYRKPLDGAKNNTDENKDESEKRKSPRSPKKMKTECDSEQGETRDADATAGAAAGAMELSKEPEKKDQDVKELLDSDNDKSFKEEPMEIDDTIKTESHVSSLESTEVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIRQFTLEEKQRLEKLKLESGVKGAGKPPMGALKSSSESPGSTKASEGHQGDSLRQEQSPSSSQASTVDLGLGGSQSDPLVLGISPPSLSTHKPDPKDQVLDDVSIQSPGPNCQRQNSVESDLDARISEPAGKGLELSQTKTEVTDSSSDDSKPTSADDVGILICKSRKLHSQDDSSTVVSSS-KSTLPASVPKSPRDRDARAFSKAVDFDGRLGGDSEYSSTLENSSDNMCIRDSAEEDMVVQNSSEATSKRFIAPEQGGESVESTKCQVVS-KSTENCEDKLQGKVTEANGKKLGQHPPKPEERAVNRCTDQVSLRHSVDRKNSEPRESEKKGQKANKFQINGKDSKAKGYLKGPGTKDGSDGKVVSSAVEPKVNNINKVIPGN-TKSLAGKESAAKPFINGDIIMEELSEQNTSETNSYSLSSSDAKGNHQDGLHTLPSTKESASTQVITPRAPCPDRNSLSQVEDMETE---SPEVKRVIPSPVRTGEGSNLSKGFMDDNGLPSSKDENVNGESQRKTVITEVTTMTSTVATESKTVIK-----VAKGDKQTVVSSTENCARSTVTTTTTTVTKLSTPSPDTGVDTISVKEQSKTVVTTTVTDSLTTAGSTLVTSMTVSKEYSTRDRVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRP-----TFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGSTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIESWVAEEELELWEIRAFAERVEKEKAQAAEQ--------------------------QTKKRLEQQKPAVIAASTTSPANNTSSTVSPAQKVMVAPLSGSVTPGTKMVLATKVGSPATVTFQQNKNFHQTFATWVKQGQ----------------------------------------------------------SNSGMVQVQQKVLGIIPSTTGPSQQTFTSFQPRTATVTIRPNTSASAGTTTTSQVITGPQIRPGMTVIRTPLQQP-ALGKAIIRTPVVVQPGTPQQVVTQIIRGQPVSTAISAPSTASSAPVQKGLTPGAAAGPLQPSAPHSPRPQQGQVKLTMAQLTQLTQG-HGGNQGLTVVIQGQGQTTGQLQLIPQGMTVLPGPGQQLMQAAMPNGTVQRFLFTPLSTSATAASSSSNSSSTTTNATAAGSGEQKQSKILPQTQVQPATTLAPTQSSSVSPAEAQPQPAQPAAQPQPQPQPP--------AQPEVQTQPAVSSHVPSETQPSQAQTSKPLVATQCQPQSSVQGQSPVRVQSPPLTRIRPSTPSQVTPGQQPQVQTTASQPIPIPPPTSLQAPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVLSPSCP-----QPQPQVIAVPQLQQ-VQVLSQIQSQVVAQIQAQQ---SGVPQQIKLQLPIQVQQNS--AAQT---QSVVTVQAASVQEQLQRVQQLRDQQQKKKQQ-IETEREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKTMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNASKLSALLFKHKEQLKAEILRKRALLDKELQIQVQEELKRD-LKMKREREMAQAVQANAASVPTPSVPAPVPAPAPA--APPAPPRSPPPSTHSLPPAGHPTAPLPVTSQKRKREEEKDS--KSKKKKMISTTSKEAKKDTRLYCICKTPYDES----------------------------------------------------------KFYIGCDRCQNWYHGRCVGILQSEADLIDEYVCPQCQSTEDA-MTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERIQKRYYEKLTEFVADMTKIFDNCRYYNPRDTPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12830-1", "uniprot_id": "BPTF_HUMAN", "id": "Q12830-1", "name": "Nucleosome-remodeling factor subunit BPTF", "aln": "MRGRRGRPPKQPAAPAAERCAPAPPPPPPPP------------TSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAPGRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEE--EEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMED-DDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHH-VLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIIEEDTENENEKKIWYYSTKVQLAELIDCLDKDYWEAELCKILEEMREEIHRHMDITEDLTNKARGSNKSFLAAANEEILESIRAKKG-DIDNVK--SPEETEKDKNETENDS-KDAEKNREEFEDQSLEKDSDDKTPDDDPEQGKSEEPTEVGDKGNSVSANLGDNTTNATSEETSPSEGRSPVGCLSETPDSSNMAEKKVASELPQDVPEEPNK-TCESSNTSATTTSIQPNLENSNSS---SELNSSQSESAKAADDPENGERESHTPVSIQEEIVGDFKSEKSNGELSESPGAGKGASGSTRIITRLRNPDSKLSQLKSQQ-VAAAAHEANKLFKEGKEVLVVNSQGEISRLSTKKEVIMKGNINNYFKLGQEGKYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLENNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQ---EEEETMQQATWVKYTFPVKHQVWKQKGEEYRVTGYGGWSWISKTHVYRFVPKLPGNTNVNYRKSLEGTKNNMDENMDESDKRKCSRSPKKIKIEPDSEKDEVKGSDAAKGADQNEMDISKITEKKDQDVKELLDSDSDKPCKEEPMEVDDDMKTESHVNCQESSQVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIKQFTLEEKQRLEKIKLEGGIKGIGKTSTNSSKNLSESPVITKAKEGCQSDSMRQEQSPNANNDQPEDLIQGCSESDSSVLRMSDPSHTTNKLYPKDRVLDDVSIRSPETKCPKQNSIENDIEEKVSDLASRGQEPSKSKTKGNDFFIDDSKLASADDIGTLICKNKKPLIQEESDTIVSSS-KSALHSSVPKSTNDRDATPLSRAMDFEGKLGCDSESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFRTREQDVEVLEPLKCELVSGESTGNCEDRLPVKGTEANGKKPSQQK-KLEERPVNKCSDQIKLKNTTDKKNNENRESEKKGQRTSTFQINGKDNKPKIYLKGECLKEISESRVVSGNVEPKVNNINKIIPENDIKSLTVKESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIE---TSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKTVITEVTTMTSTVATESKTVIK-----VEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRP-----TFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQ--------------------------QAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQ----------------------------------------------------------SNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQS-TLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQG-HGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTT----TTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQ---SGVPQQIKLQLPIQIQQSS--AVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRD-LKIKKEKDLMQLAQATAVAAPCPPV-----TPAPP--APPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDES----------------------------------------------------------KFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDA-MTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQI5-1", "uniprot_id": "A0A8M3AQI5_DANRE", "id": "A0A8M3AQI5-1", "name": "", "aln": "MRGRRGRPPKAQLVQEPS--------------------------TGPVRGLRPRRSLKPKVKGGSDEDYVTPKRGTHHHSTRGRRK--------ARSTASR----GRGRGRGTARGRGR----------RSTASGVVYDDHESDEDDE--DAVSLR---SEEDEYIEEPLTDEEEEEEEEEAINDESDYLEELDELDEDDASYCTESSHG-----SNTVGRKRPRPRRPPSPILEQKEIPLLELPNSSEDLLLPNEQLLNALAIYEVLRSFCTVLRLSPFRFEDFCAALVGQEQCTLMAETHICLLKAILREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVVRSYCESDPEYHH-VLPDLEGEDYPFSPLESKIKVLQFLVDQFLTTNLAREELMSEGVIQYDDHCRVCHRLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEICVAHKVPGVTDCLTEFQKSRPYIRQEPIGFDRHQRKYWFLNRRVVVEEDGEDDS-KQIWYYSTKVQLGELLELLDKGFWENDLCSVLEEMREEIHAHMDITEELTNKARGNNKAYLTVANDVILDRLKTKQEAELEEVKRRAAEEAERAKLEPKTLSDEPASGDQMSSNDSCPQQDSSNGNARNE--QTSSDASVSAVPVGEVLSSSVPEIAASSSSTVQTKPDSQSPIG--NAVTSSSSGEEKGEGTDGVEELTGKSSEGACHGEGDSVLEAELAQTADENSCS-----SHFSISECLRGPDEPDLVDRSSQSSLNSQDDTG----DGKANGDSTKT--------ASSRMITRLRNPDSKLSQRKVMQDKDGSSQDGSRALKETP---PLSSFGTFKRDSSK--------SSGFFKLGQEGKFRVYHNQYSTNTLALNKHQHREDHDKRRHLSHKLCMTPAGEFKWNGSLYGSKALTVSTLRLTIIQLENNIPAPFLHPNWASHRSNWIKAVQMCSKAREFALALAILECAIKPVVMLPVWKDSLGHTRLHRMTSVEREEKEKVKKREKKL---EDEETMQQATWVKYTFPIKHQVWKQKGEEYRVTGYGGWSWVSKTHVHRFFTKLPGNTNVNYRKALEAAKTGMDNQAALPGAPKTVVKKDEMSSQNVPDKDNAQVLSLDSSEEKLSVEKDHVLKVEEQDEEKMNETTEEKCNEKN--ESVEEMDTSSPNSANEG-KVEITNAST----------DDSTMKEEPLDSEVVKDNTLNQPQ-----------QCFWHDVVNVSEGFLQRTAYKKLKPSKLDGLLERRVKQFTIEEKQ--------------------RIDKLKQAPTSKPLTETAVENKETTLAAQD----------------------HKVKIEGTISETPKARQTEGVACLAIQEKD---------------------------------------NVVKRLVFNQEDEQAKTNTSGQKNTLDVRLNDSVELAPKENQQKLAETDPKTAS--------------------RVAMSELNGNSQSLDQSLSLNAKPDKNITEATCPPEDSAGKDNIENSENDLDVKKTVPVQVNGKDVTVDPECKN--LTDNGDTKELTNTIVEDIKAISPKEPVKSLMNGDATQECLKEWTNSTIPQVNLDEEKAVTKLDPDYPPPQKVAKLENNIEKPIDSSVSLSVPEPSPVASEPNERSEVPSHSSKVEPMQVVEAKPSVPSPVPSAEESSLSSDLTE--------NSSSIGET---TVVTQVTTTTTTVSTESRMVLTSRDSLASKNGLNTAVLTDSKVESSSSVSTLSSTTTTTVTKVLSSSQEATLTTECKTMVMKTLTDTTSSPSGSTVKSMTVSHEYSTRDRVRLLKFSRTKKTRSGTALPSYRKFVTKSSKKSIFVLPNDELKKLARRGGIREVPIFNYNAKPALDIWPYPSPRP-----TFGITWRYRLQTVRSLAGVSLMLRLLWACLRWDDMSVKPSPTGGTTRTETSDTDITTTEIIKRRDVGPYGIRSEYCIRKIICPLGVPETPKETPTPQRKGLRSSALRPKKPEPAKQTGPVVIETWVAEEDLELWEIRAFTERVEREKAQAADPTKVSVQKKAEEVKAQLEAQLKQQRLAAQQKRLEQQKPSTTSN-TTTLTSTPTTPGTTTQKVVVGSISGQVTSTPKVVMTTKLGSP--VTFQQNKNFQQSFASWVKQGQQGNSVSTSSVVTVAASSATTSGQTFHIAAAPGSMAGSVIAAKLPVPANSKIVTVNVPTTQGGLVQVQQKVVGIIPSSTAGNAQSFPPFQPRTATINIRPNTT----TSTQQVLTTGTTLRPGMTVIRSPLQQATTLGKTIIRTPLMVQQGQTQQQVQTSSGTQVVGTPPRLP-----TPNQ----------PQTPQTPASPRPQQGQVKLTLAQLTQLTQGAQGGNQGLTVVIQGQGQTTGQLQVIPQGVTVIPGPGQQLMQAAMPNGQVQRFLFTPMAPAPTPAPAPVS---------------------APAAPSNTTPSSVPPAAAPTAVTSTTPAPIQTAARLAPQPQPP-----------------------PSLPPPPSVPPSQPVQHTPAPIQTAVIPQP-----TPP---IQPHPPVQLRPQPQLPPQNPVVPPTPVSTPQIAQVTATAPPQQITTLPVTQTTVTKVQPQIQLP---------------PQLLSVPGLQQ--QVLSHIQSQVAAQIQAQVGTTAGMPQQIKLQLPIQIQQQGGGQVQAHQIQNLVTIQTASVQEQLQRIQQLCEQQQQKKKQ-QEAKREQAQQHVSQSDLIQKQVAQKQNVAIEQLKQKKTMTPAEREENQRMIVCNQVMKFILDKIDKDERQAAKKRKREESVEQKRSKQNASKLSALLFKHKEQLKADILKKRALLDKELQLQVQEELKRDLIKLRREKEKAQAAAAQAAAA-------------------AAAAAAASTHVHSGLSSYTGTVTSPTSTHKRKREEERDAA-KPKRKKMISTTSKDSKRDIKLYCICKTPYDESKFYIGCDLCSNWYHGECVGITEKEAKKMDDYICSECKRAQEGNTEELYCICRTPYDESQFYIGCDRCQNWYHGRCVGILQSEATHIDEYVCPQCQSTEDA-MTVLTPLTDKDYEGLKRILRSLQSHKMAWPFLEPVDPNDAPDYYGIIKEPMDLSTMEERIQKRFYSKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEFLESFFVQKLKAFKASRSHNNKLQSSAS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0T1-1", "uniprot_id": "NU301_DROME", "id": "Q9W0T1-1", "name": "Nucleosome-remodeling factor subunit NURF301", "aln": "MSGRGSRKRGRPPKTPNER-------------------------ASGRFNYQLLKKPKYLSEGKSQPSTPSASRGISPQSD-------------EGSRSSHNNHTNRSRGSAAKRGRGR--------------KSAVQPNTSS---------------YSGRKGYESEYHYGSDFGDSEEDKSDNEDDMLLTPSDDESLEVANESESEFSVCSFNQNGVGRPPRPPSPEPVWLQEGRQYAALDLPDSSEDLFIANTHVLRALSIYEVLRRFRHMVRLSPFRFEDLCAALACEEQSALLTEVHIMLLKAILREEDAQGTHFGPLDQKDTVNISLYLIDSITWPEVLRSYVESDKTFDRNVFHILSHTEYPYTGIDNRLEVLQFLSDQFLTSNSIRDVMLQEGPIHYDDHCRVCHRLGDLLCCETCPAVYHLECVDPPMNDVPTEDWQCGLCRSHKVSGVVDCVLPQEKQGVLIRHDSLGVDRHGRKYWFIARRIFIE----DQENFTCWYYSTTSKLKLLLSRLDAEELETRLHSQITERRDEIERQMKLTETLTNEHKHTKRSVIEIEQEAKNELLEKEVLDEDEKDG--------------------DAKSESQSIEGTKKQEE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------CKMVTRQKSNQLTNG-------------------------------------------------TLHFKLGMEQGFKNYVNQYSTNPIALNKPQRNEERDKRRHLSHKFSLTTASDFKWIGITMGTTDNMITTLRQTLINFESNIAASFLNINWVVNKKIWNAAVMNARRPSEFAVVLLLFQASLKSVVFANVWHEQLGHTTLQRITSAEREERKKLEKREKRERDDEEERNRLAFNYIKYTLGLKHQVWKQKGEEYRVHGQWGWLWLSSSRRCGVRARRAQPLTHNRVYVHYTMGEENDVNEIILVDPRTQRFMQQCESSN-VDGQVCHYLPDQYKNVKVIEDVTEKIKGHIDVSKALNAPGRTYYSKVARKSRLDDLLDRRLKLAEVEEQMASKIPSDMKPLLVSSQNNTANSKQTFLEKRLLRLTEVQAKG---------GPANVNLELVNSLAKQIQTVRLQFSQLNRFAKVFRCYTKECNTNSNAVSQITQNTCYSPLCLQKARAKKELLLLLRKAHTAGNGSKETVAAILGAVK--------KPSILEQKLTEGKRESTQVAVDDSEEGKPAESEAPLDLLQDWEHARAHAVPFSDS----------------------LLTECILVDQECVTNTKIKQEVNASSGCNTTPDSNTQDSDKIDYIESMDVCSNVEIESTEDS-------------------IVTGLNSGNAEDVDMTPGWRRKRNQKSKKSYIGTKDVLDQTLDKDIPLNKQ-NRRFPITARPVKRECVKKYERETFENGNERVYSTSSPRGRVYLLN---------------DAAKLYEQAVKTEDKSTITKKPSYSRYPLISNFLTHKKKRSLLVLPRFELLKLARLGGKSSTNGFHHAAKNNTIWQYQ--CSRPLFRTCWSYRTSNATSLSSLALQLRILWSCLRWDDMIAKPPSTDGKHQVTTDTEIVTLELLKLRHS-----GRYGEKTSYLRRKVVIPLEMPKTVREVTSIRSGLRKRKRAESPQPTEPQITEEWVDEDKLELWEIKFMGEKQEKARLSAVTRSVASRQLEASGS-NGSNTSTNGALGVAGRVQLAPKLSEDVKEKMEQQLKLQRAVHQQRKLVATGEITRSVTPVKGQVIGSRRVIVKNPDGTTRIIQQAVTQVSRTGGANTAAAAASPTVGGSTSTQSNPSTSTPHKVQIIRGPDGKVSVRGLNPGQQLVQMPDGKLHVLTTTTSSNSAGQGNKMKVPIKPASTSSSPAISSAQTTTNPVTPVIKQIAVKHVTKNSATQSIASS------------------------SRVALPLAQIKNKLLLAQQQQQSTSSSPATSSSPVQKIVSKVVNTSTSGQTLQQVFVQSGSKLVVGQNAQGQKVIISTSAAQQ-----------------------------------------------------------QGTSPVQQQQLVQSQPIQQSPQQISMTQVGNQPTQKVIQQIVNTSNVQQQIVVGGQRIILSPGQTIVTQRNVPQ-SQALQMVQQQIQTQQQQQQHHVVQPQQQFVVQSNQIVQSS-----------------PSAQTKLVKQLVVQQQSQQTIEEKTQITTTDSNETGTQQVLVPN---STLAQQLAQGKLQVATVNGQQVIVKPLGNNQAQIVAHIKHQGDGNAHIVTSN--------------------------SATAVPQANPQTSPVKQQALPPQSPQQVVVQQQQIHQQ------------------SPTNFESGVTPITQQPVLTQAVQAPAQQQALSVEESLLQNQPPGTVIKCVTAQVLQTEHGPRIVLQGLVGNDFTAQQLQLVQTQVKQQLMKAQESNGKLGVLGPTKIYLAVQ-------------PENAVQSQPPPLTPVHQSAAHQQTNNIEIDADTLATTYEANSTIKDIAINNGDDQENSKCAETENSNITTNESFAGTSSLLEGSEHDEPTNLAGLDISETDLENKQNESFVVTRGYIQKS---ISNALKQGNLSPELEEK----LVCMQKQQENANSTNEWETCSRGSVNEEALTPSRQTDDTEWKIRTSLRRPNAMTTSSQFNRILKKNRSKNDEVAELGEQKQSQLERHKELLKKNILRKRSLLERNLQS-----------EIHEDVKTKVQRHVRPLSNASPDEQSENERSGEPNLDFKRTEVQNPRHGAGRPKKLTRKKEKLYCICRTPYDDTKFYVGCDLCSNWFHGDCVSITEEASKKLSEFICIDCKRAR--ETQQLYCSCRQPYDESQFYICCDKCQDWFHGRCVGILQSEAEFIDEYVCPECQRKNDANAANMKKLTSNDVEELKNLIKQMQLHKSAWPFMEPVDPKEAPDYYKVIKEPMDLKRMEIKLESNTYTKLSEFIGDMTKIFDNCRYYNPKESSFYKCAEALESYFVQKIKNFRENVFDQRT------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ** .* . :. . : : . . : :.. . :* .*. * . * * . .* : .* . .. .* ..: :.: : :::.* .: :. :.: :**.. .. ** : * :: . *::*.*****::.* :::..::****:* * ::***** ***:****. :**.:*::* *: ****:*****:..* *** * **:** :**:**.:*****:* * *** :.: *: . :**: ::.:::***** *****:* *: ::.** *:*********:**********.********.**:::** ::*** :* :***.**.**: :*. :*::.:* ** *****: **:.:* ::. *****. :* *:. ** * * : : *:*:. :*.:** ***: : .::: : :: : :. : : : *. . . :. ::: :::** :. : . . . .**** * :: * ******.:**** *:.*::******:**:.:*.*.:*** * *:. ::*** *: ::*.**.:.**: **. :: * ** . :. ***:.* :::.::*.**: :*::.**** *:*:** ****::*::*:**: *:*.. .::***: ::** * * ** *:*.:: . .: . . * * : : .: . . : : : . : . . : : . : . : : . :: * . . * * .. :: :: . : . . :. : . : : : .. . . ..: : * .:: * . .. . . : : .. .*. * :* : . . : . : ..*.:. . : : .. .: : : :: . . . : : .: :. : :. .. : : :. . : . : . .: . . :. .: : : * : * . . .. .:. :*** * *: * : : . :* . .* .*. . : : . *. . : . . . *: : : ... : .*: .: : . . : *.:* :*: :: ::.. : : .: :* :* : : : *.: : . : .. : . . :*:::.* : ..:**: * : : : * * .. . *.:.: * .. * :* ....: .: .:: : : *. . .:.. :*: * * * :...:.. :.: : . ..:. : : . : * :.. ** : :: : : * :. **::: * . . ::. . :.: *: .. : ** *:: : . ::: : * *: : * : * * : *: : **:* . . *:: . :* *: : * . ***:: .: *. .* . . .. . . . ::.. * . * . * : * * . . * : : *. *: .. : . . . : * . . :. *: . * . * . :*: : . : . : ::: . . . .: : . . : : :::: .: : .. . : .:* :: : * *.: :: .::* .*: :** * : :. :: * : . :.* . .:::.:. *: : * : : :. :.: ::. : :* * ::. ::.:.:: : : . . . . :. : : : . : :: . ..* :::. :*****:****:: :*** **:**:*:************ *******:** .:** : :. **.:* * **.:::.:* ** ****:*****::***** :******* ** ::: . * **:**:.************** ::.**:*** ***:****:* *: . .:.. ", "identical_positions": 469, "similar_positions": 751, "identity": "14.43%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3205", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZG27-1", "uniprot_id": "UBIA1_RAT", "id": "D3ZG27-1", "name": "UbiA prenyltransferase domain-containing protein 1", "aln": "MAAVQAPGEKINIQAGETTQVGDTDQQRNDWPEEDR--------------LPERS-WRQKCASYVLALRPWSFSASLTPVALGSALAYRSQGVLDPRL--LLGCAVAVLAVHGAGNLVNTYYDFSKGIDHKKSDDRTLVDRILEPQDVVRFGVFLYTLGCVCAAYLYYLSTLKLEHLALIYFGGLSGSFLYTGGIGFKYVALGDLVILITFGPLAVMFAYAVQVGSLAIFPLVYAIPLALSTEAILHSNNTRDMESDREAGIVTLAILIGPTLSYILYNTLLFLPYLIFTILATHCSISLALPLLTSPMAFSLERQFRS-QAFNKLPQRTAKLNLLLGLFYVFGIILAPAGSLPRL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DC60-1", "uniprot_id": "UBIA1_MOUSE", "id": "Q9DC60-1", "name": "UbiA prenyltransferase domain-containing protein 1", "aln": "MAAVQAPGEKINILAGETAKVGDP--QKNEWPEQDR--------------LPERS-WRHKCASYVLALRPWSFSASLTPVALGSALAYRSQGVLDPRL--LLGCAVAVLAVHGAGNLVNTYYDFSKGIDHKKSDDRTLVDRILEPQDVVRFGVFLYTLGCVCAACLYYLSALKLEHLALIYFGGLSGSFLYTGGIGFKYVALGDLVILITFGPLAVMFAYAVQVGSLAIFPLIYAIPLALSTEAILHSNNTRDMESDREAGIVTLAILIGPTFSYVLYNTLLFVPYLIFTILATHCSISLALPLLTIPMAFSLERQFRS-QAFNKLPQRTAKLNLLLGLFYVFGIILAPAGSLPRL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5Z9-1", "uniprot_id": "UBIA1_HUMAN", "id": "Q9Y5Z9-1", "name": "UbiA prenyltransferase domain-containing protein 1", "aln": "MAASQVLGEKINILSGETVKAGDRDPLGNDCPEQDR--------------LPQRS-WRQKCASYVLALRPWSFSASLTPVALGSALAYRSHGVLDPRL--LVGCAVAVLAVHGAGNLVNTYYDFSKGIDHKKSDDRTLVDRILEPQDVVRFGVFLYTLGCVCAACLYYLSPLKLEHLALIYFGGLSGSFLYTGGIGFKYVALGDLIILITFGPLAVMFAYAIQVGSLAIFPLVYAIPLALSTEAILHSNNTRDMESDREAGIVTLAILIGPTFSYILYNTLLFLPYLVFSILATHCTISLALPLLTIPMAFSLERQFRS-QAFNKLPQRTAKLNLLLGLFYVFGIILAPAGSLPKI---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FB98-1", "uniprot_id": "UBIA1_DANRE", "id": "E7FB98-1", "name": "UbiA prenyltransferase domain-containing protein 1", "aln": "MQEMKP--AALSGSNGLNGASGSSVRVPCSRLSRAG--------------RMALD-LQSKCAAYVLALRPWSFSASLTPVALGSALAYKLEGSVDLLL--LLVCAVAVLLVHGAGNLVNTYYDFSKGIDHKKSDDRTLVDQILKPQDVVMFGAVLYSAGCLCATLLYFLSSLKLEHLALIYFGGLSSSFLYTGGIGLKYVALGDVVILITFGPLAVMFAHAVQVGYLSVLPLVYAVPLALNTEAILHSNNTRDMDSDKQAGIVTLAILLGPTLSYVIYNLLLFVPYLLFCILATRYTISMALPLLTLPMAFPLERQFRC-RCYAKIPQKTAKLNLLMGLFYVFGIILAPQGSLPLL---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3R8-1", "uniprot_id": "UBIA1_DROME", "id": "Q9V3R8-1", "name": "UbiA prenyltransferase domain-containing protein 1 homolog", "aln": "MATSSQLLPNGNLSRNGKTKTEDGEEVEAVVGARAAGADAGVALTGRLTGHPSTSGTFMKLKTYLLALRPWSLSASLVPTLLGSALAYRSQWAEEFSLATFFLTAFTVVTVHCAGNVVNTYFDFIKGIDKQKADDRTLVDHILTKDEVVSLGAILYMAGCGGFVLLAVLSPAKMEHLALIYFGGLSSSFLYTGGIGFKYIALGDLVILILFGPISVLFAFMSQTGHLDWTTMGYAIPLALNTEAILHSNNTRDADNDRRAGIVTLAILIGRTASHVLYAMLLFAPYSLFFIFGLKYSLWFLLPLVTLPQAFQIEKRFRNEQTMHLVPRQTAKLNFFFGILYVVACCCAHQLPTFGLRRN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . . . . . . * :*:*******:****.*. *******: . : * :. *.:*: ** ***:****:** ****::*:*******:** ::** :*..** ** . * **. *:************.*********:**:****::*** ***::*:**. *.* * .: **:****.************ :.*:.*********:* * *:::* *** ** :* *:. : :: : ***:* * ** :*::** : :*::*****:::*::**.. * . : ", "identical_positions": 159, "similar_positions": 80, "identity": "44.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3207", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LNY6-1", "uniprot_id": "F1LNY6_RAT", "id": "F1LNY6-1", "name": "Transcription initiation factor TFIID subunit 2", "aln": "--MPPTGLESSRMNRKKGDKGFESPRPYKLTHQVVCINNINFQRKSVVGFVELTIFPTVANLNRIKLNSKQCRIYRVRINDL-EAAFIYNDPTLEVCHSESKQRNLN--------YFSNAYAAAVSAVDPDAGNGELCIKVPSELWKHVDELKVLK------------------------IHINFSLDQPKGGLHFVVP--SVEGSMAERGAHVFSCGYQNSTRFWFPCVDSYSELCTWKLEFTVDAAMVAVSN----------------------------------------------------------------------------------------------------GDLVETVYTHDMRKKTFHYVLAIPTAASNISLAIGPFEILVDPYMH------------------------------------EVTHFCLPQLLP---LLKHTTSYLHEVFEFYEEILTCRYPYSCFKTVFIDEAYVEVAAYASMSIFSTNLLHSAMIIDETPLTRRCLAQSLAQQFFGCFISRMSWSDEWVLKGISGYIYGLWMKKTFGVNEYHHWIKEELDKIVAYELKTGGVLLH------PIFGGGKEKDNPASHLH-----FSIKHPHTLSWEYYTMFQCKAHLVMRLIENRISMEFMLQVFNKLLSLASTASSQKFQSHMWSQMLVSTYGFLKSISNVSGKDIQPLIKQWVDQSGVVKFYGSFAFNRKRNVLELEIKQDYTSP-GTQKYVG-------------------------PLKVTVQELDGS-FNHTLQIEENSLKHDIPCHSKSRRNKKK-------------------------------------KIPLMNGEEVDMDLSAMDADSPLLWIRIDPDMSVLRKVEFEQADFMWQYELRYERDVVAQQESILALEKFPTPA------SRLALTDILEQEQCFYRVRMSACFCLAKIANSMVSTWTGPPAMKSLFTRMFCCKTCPNIVKTNNFMSFQSYFLQKTMPVAMALLRDVHNLCPKEVLTFILDLIKYNDNRKNKFSDNYYRAEMID-----ALANSVTPAVS--VNNEVRTLDNLN----PDVRLILEEITRFLNMEKLLPSYRHTITVSCLRAIRVLQKNGHVPSDASLFKSYAEYGHFVDIR--IAALEAVVDYTKVDRSYEE---LQWLLNMIQTDPVPYVRHKILNMLTKNPP-FTKNMESPLCNEALVDQLWKLMNSGTAHDWRLRCGAVD--LYFTLFGLSRPSCLPLPELGLVLN--LKEKKAVLNPTIIPEAGVGNQET-----------------------------------------ASNPGCHTQLAGFQNPFSSSQDEEEVDMDTVHDSQAFISHHLNMLERPSTPGLSKYRPSSSRSSLMPQHALGCDITPTTKPQWSMELSRKGAGKE-QPLEMGVHPVAAPLSVFAKEALSSARHSEHHHHHHHEHKKKKKKHKHKHKHKHKHDGKDKDKDKE-----------------PFTFS-SPASGRSVRSPSLSD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C176-1", "uniprot_id": "TAF2_MOUSE", "id": "Q8C176-1", "name": "Transcription initiation factor TFIID subunit 2", "aln": "------------MNRKKGDKGFESPRPYKLTHQVVCINNINFQRKSVVGFVELTIFPTVANLNRIKLNSKQCRIYRVRINDL-EAAFIYNDPTLEVCHSESKQRNLN--------YFSNAYAAAVSAVDPDAGNGELCIKVPSELWKHVDELKVLK------------------------IHINFSLDQPKGGLHFVVP--SVEGSMAERGAHVFSCGYQNSTRFWFPCVDSYSELCTWKLEFTVDAAMVAVSN----------------------------------------------------------------------------------------------------GDLVETVYTHDMRKKTFHYMLTIPTAASNISLAIGPFEILVDPYMH------------------------------------EVTHFCLPQLLP---LLKHTTSYIHEVFEFYEEILTCRYPYSCFKTVFIDEAYVEVAAYASMSIFSTNLLHSAMIIDETPLTRRCLAQALAQQFFGCFISRMSWSDEWVLKGISGYIYGLWMKKTFGVNEYHHWIKEELDKIVAYELKTGGVLLH------PIFGGGKEKDNPASHLH-----FSIKHPHTLSWEYYTMFQCKAHLVMRLIENRISMEFMLQVFNKLLSLASTASSQKFQSHMWSQMLVSTYGFLKSISNVSGKDIQPLIKQWLDQSGVVKFYGSFAFNRKRNVLELEIKQDYTSP-GTQKYVG-------------------------PLKVTVQELDGS-FNHTLQIEENSLKHDIPCHSKSRRNKKK-------------------------------------KIPLMNGEEVDMDLSAMEADSPLLWIRIDPDMSVLRKVEFEQADFMWQYELRYERDVVAQQESILALEKFPTPA------SRLALTDILEQEQCFYRVRMSACFCLAKIANSMVSTWTGPPAMKSLFTRMFCCKTCPNIVKTNNFMSFQSYFLQKTMPVAMALLRDVHNLCPKEVLTFILDLIKYNDNRKNKFSDNYYRAEMID-----ALANSVTPAVS--VNNEVRTLDNLN----PDVRLILEEITRFLNMEKLLPSYRHTITVSCLRAIRVLQKNGHVPSDASLFKSYAEYGHFVDIR--IAALEAVVDYTKVDRSYEE---LQWLLNMIQTDPVPYVRHKILNMLTKNPP-FTKNMESPLCNEALVDQLWKLMNSGTAHDWRLRCGAVD--LYFTLFGLSRPSCLPLPELGLVLN--LKEKKAVLNPTIIPEAGVGNQ-----------------------------------------------------------FSSSQDEEEVDMDTVHDSQAFISHHLNMLERPSTPGLSKYRP-------------------------------------------------------------------HHHHHHHEHKKKKKKHKHKHKHKHKHD--SKDKDRE-----------------PFAFS-SPASGRSVRSPSLSD----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P1X5-1", "uniprot_id": "TAF2_HUMAN", "id": "Q6P1X5-1", "name": "Transcription initiation factor TFIID subunit 2", "aln": "--MPLTGVEPARMNRKKGDKGFESPRPYKLTHQVVCINNINFQRKSVVGFVELTIFPTVANLNRIKLNSKQCRIYRVRINDL-EAAFIYNDPTLEVCHSESKQRNLN--------YFSNAYAAAVSAVDPDAGNGELCIKVPSELWKHVDELKVLK------------------------IHINFSLDQPKGGLHFVVP--SVEGSMAERGAHVFSCGYQNSTRFWFPCVDSYSELCTWKLEFTVDAAMVAVSN----------------------------------------------------------------------------------------------------GDLVETVYTHDMRKKTFHYMLTIPTAASNISLAIGPFEILVDPYMH------------------------------------EVTHFCLPQLLP---LLKHTTSYLHEVFEFYEEILTCRYPYSCFKTVFIDEAYVEVAAYASMSIFSTNLLHSAMIIDETPLTRRCLAQSLAQQFFGCFISRMSWSDEWVLKGISGYIYGLWMKKTFGVNEYRHWIKEELDKIVAYELKTGGVLLH------PIFGGGKEKDNPASHLH-----FSIKHPHTLSWEYYSMFQCKAHLVMRLIENRISMEFMLQVFNKLLSLASTASSQKFQSHMWSQMLVSTSGFLKSISNVSGKDIQPLIKQWVDQSGVVKFYGSFAFNRKRNVLELEIKQDYTSP-GTQKYVG-------------------------PLKVTVQELDGS-FNHTLQIEENSLKHDIPCHSKSRRNKKK-------------------------------------KIPLMNGEEVDMDLSAMDADSPLLWIRIDPDMSVLRKVEFEQADFMWQYQLRYERDVVAQQESILALEKFPTPA------SRLALTDILEQEQCFYRVRMSACFCLAKIANSMVSTWTGPPAMKSLFTRMFCCKSCPNIVKTNNFMSFQSYFLQKTMPVAMALLRDVHNLCPKEVLTFILDLIKYNDNRKNKFSDNYYRAEMID-----ALANSVTPAVS--VNNEVRTLDNLN----PDVRLILEEITRFLNMEKLLPSYRHTITVSCLRAIRVLQKNGHVPSDPALFKSYAEYGHFVDIR--IAALEAVVDYTKVDRSYEE---LQWLLNMIQNDPVPYVRHKILNMLTKNPP-FTKNMESPLCNEALVDQLWKLMNSGTSHDWRLRCGAVD--LYFTLFGLSRPSCLPLPELGLVLN--LKEKKAVLNPTIIPESVAGNQEA-----------------------------------------ANNPSSHPQLVGFQNPFSSSQDEEEIDMDTVHDSQAFISHHLNMLERPSTPGLSKYRPASSRSALIPQHSAGCDSTPTTKPQWSLELARKGTGKEQAPLEMSMHPAASAPLSVFTKESTASKHSDHHHHHHHEHKKKKKKHKHKHKHKHKHD--SKEKDKE-----------------PFTFS-SPASGRSIRSPSLSD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q32PW3-1", "uniprot_id": "TAF2_DANRE", "id": "Q32PW3-1", "name": "Transcription initiation factor TFIID subunit 2", "aln": "------------MNRKK-DKGFESPRPYKLTHQVVCINNVNFQRKSVIGYVELTIFPTVVNLNRIKLNSKQCRIYRVRVNDL-EAPFIYNDPTLEVCHHESKQRNLN--------YFSSAYTAAVSAVDPDAGNGELSIKVPSELWKQGDEMKVMK------------------------VYIEFSLDQPKGGLHFVVP--DVEGNMAERAAHVFSFGNQNSSRFWFPCVDSYSELCTWKLEFTVDASMVAVSC----------------------------------------------------------------------------------------------------GDLVETVYTHDMRKKTYHYMLPIPTAAPNISMAVGPFEILVDPYMH------------------------------------EVTHFCLPQLLP---LLKHTMSYLHEIFEFYEEILTCRYPYSCFKTVFVDEAYVQVSSYASMSIFSTNLLHSGLIIDQTPMTRSFLAQALAQQFFGCFISRMSWADEWVLKGISGYIYGLYLKKTFGVNEYRHWIKEELDKIVEYELKIGGVLLH------PTFSGGKEKDNPTPHLH-----FSIKHPHTLSWEYYKMFQCKAHLVMRLIENRISMEFMLQVFNKLLSLASTASSQKYQSHMWSQMLVSTSGFLKSISNVSGKDIGPLIKQWVDQSGVVKFFGSFAFNRKRNVLELEIRQDYTSS-GTQKYVG-------------------------PIKVTVQELDGS-FNHTLQIEENSLKHDIPCHSKSRRNKKK-------------------------------------KIPLMNGEEVDMDLSAMDADSPLLWIRIDPDMSILRKVEFEQADFMWQYQLRYERDVVAQEEAILALEKFPTPP------SRRALTDILEQDQCFYKVRMHACFCLAKIANSMVSTWTGPPAMKSLFTRMFCCKSCPNIVKTNNFISFQSYFLQKTIPVAMAQLRDVQNLCPREVLSFILDLIKYNDNRKNKFSDNYYRAELID-----ALTNSLTPAIS--INNEVRTVDSLN----ADVRLILEEITRFLNMEKLLPSYRNTITVSCLRAIRMLQKNGHIPSDPTLFKSYAEYGHFVDVR--IAALEAVIDYTRVDRSSSE---LQWLLDLVQNDPVHYVRHEILSMLAKNPP-FTKAADSSLCNEALVDQLWKLMNSGTCHDWRLRCDAVN--LYYTLFGLTRPSCLPLPELGLVLN--LKEKKAVLNPTIKSEQIPGLPEMTPSMTFINTLKEEHVVMDPALSGVAMAPLSLKRKAETPVGSAPEPGQVLQEEPSAKITLKSREEEDIDMDTVHDSQAFIYHHLNMLERPSTPGKEPSSVEQAILS---------------------------------------MPGTPMPTLSKESTSSKHGEHHHHHHHHHEHKKKKKKHKHKHKHKHKHE--SKDKDRD-----------------SHAFVNSPASGLSIRSPSLSD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24325-1", "uniprot_id": "TAF2_DROME", "id": "Q24325-1", "name": "Transcription initiation factor TFIID subunit 2", "aln": "-------------METQPEVPEVPLRPFKLAHQVVSLTGISFERRSIIGVVELTIVPNSENLRLIRLNAKQLRIYSVVLNDVCQADFTYFDPFQNICYKEHKSRALE--------VYSKHHLTAAQYTDPDVNNGELLIQVPPEGYSMIQEGQGLR------------------------IRIEFSLENPKCGVHFVIPPASTDEETQMNSSHMFTNCYENSSRLWFPCVDSFADPCTWRLEFTVDKNMTAVSC----------------------------------------------------------------------------------------------------GELLEVIMTPDLRKKTFHYSVSTPVCAPNIALAVGQFEIYVDPHMH------------------------------------EVTHFCLPGLLP---LLKNTVRYLHEAFEFYEETLSTRYPFSCYKQVFVDELDTDISAYATMSIASVNLLHSIAIIDQTYISRTFMSRAVAEQFFGCFITSHHWSDTWLAKGIAEYLCGLYSRKCFGNNEYRAWVQSELARVVRYEEQYGGIILDCSQPPAPLPVSGTNQSAASSKQQEIVHYFPIKSLHTVSPKYVEAMRRKAHFVIRMLENRIGQELLIQVFNKQLALASSAATTKIGAGLWSQLLISTNIFIKAIFTVTGKDMSVFMDQWVRTGGHAKFSLTSVFNRKRNTIELEIRQDYVNQRGIRKYNG-------------------------PLMVQLQELDGT-FKHTLQIESTLVKSDITCHSKSRRNKKK-------------------------------------KIPLCTGEEVDMDLSAMD-DSPVLWIRLDPEMILLRDLIIEQPDFQWQYQLRHERDVTAQFQAIQALQKYPTNA------TRLALTDTIESERCFYQVRCEAAHSLTKVANQMVASWSGPPAMLNIFRKFFGSFSAPHIIKLNNFSNFQLYFLQKAIPVAMAGLRTSHGICPPEVMRFLFDLFKYNENSRNHYTDAYYRAALVE-----ALGETLTPVVSVAIHGTQITTDSLS----TDAKLVLDEVTRLLNMEKHLPSYKYMVSVSCLKVIRKLQKFGHLPSLPHIYRSYAEYGIYLDLR--IAAMECLVDFVKVDGRSED---LEHLITLLETDPDPAARHALAQLLIDNPP-FTRESRSRLDKPNLVDRLWFSINR-LPYDTKLRCDIVD--LYYALYGTKRPNCLQAGENQSFYKDLMKDNNSSVGSVTGSFKKTSDSKS--------------------------------------HLPTPTNTLDNEPQERQKPAMVTIKRTATEAFEVGDEIIKLERSEEITVLDEPVNVQAYDSETKVNALQADEEARDTHQAAKRLKNEMYAEDDNSS----------TMLDVGDSTRYESSHEEGKLKSGDGGLKKKKKKEKKKHKHKHKHRHSKD-KDKDKDKERKDKDKRDPHISRLQARETATPDTLSSEDSSNSNSLPPMNLN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23255-1", "uniprot_id": "TAF2_YEAST", "id": "P23255-1", "name": "Transcription initiation factor TFIID subunit 2", "aln": "MMSFSKNATPRAIVSESSTLHEMKFRNFRVAHEKISLD-IDLATHCITGSATIIIIPLIQNLEYVTFDCKEMTIKDVLVENRRCDQFIHDDPLQTNLNGLTSQNVLYSDNSIEQSHFLRSKFASLNEYPETDSKSQLTIKIPSSIKISLEDANALSNYTPITPSIKTTPGFQESVFTPITLQIEYEIRNPKSGIKFDTV---YADKPWLWNVYTSNGEICSSASYWVPCVDLLDEKSTWELEFSVPRLVKNIGTSKLIGQNGEESEKEKEDTPEHDEEEEGKPARVIKDEDKDSNLKNDEEGKNSKSKDAQDNDEEEEEGESDEEEEEGEEERRNIEESNNPSLRDVIVCCSEYSNIKELPHPIDLTKKKCIFQIINPVAPHHIGWAIGAFNSWSLPLISPPSVDAEDEVEEDKLRENVVDNVNDTMDDDIGSDIIPIQIFTLPTQETDELTVINSTVVCQKIIDFYSKEFGS-YPFTCYSMVFLPTAPSKHMDFAALGICNTRLLYPLEVIDKAFSTTNELAWALANQWSCVNITPLDMNDYWCCLGIAGYMVFQVTKKLMGNNTYKYQLKRNSEAIVEQDFEKP-----------PIGSTFTGSSRPISWSS----------------KDLSFIQLKAPMILHILDRRMTKTERSFGMSRVLPKIFLQAMS----GDLPNNSLTSSHFQHVCERVNKSKLENFFNEWVYGSGVPILRVTQRFNRKRMVIELGIRQVQDEELGHEKVVGEEGFFKSALDHLEHPDLNRTECFTGSMTIRIHEHDGTPYEHIVEIKDTFTKIDIQYNTKYRRLRKRGGGANDENGVENNNEEKPIVVDVNCLGNVYMSPEECSRFSLTEFNRTSESNELLKQNEAFEWIRIDSDLEWICQMHINQPDYMFSSQLRQDGDIEAQLEAIRYYEDVVVNGGVKSLVYSSILFRTAIDERYFFGIRLAACEALSKYVYDPDFTG-GVKHLIQIFQILFCLEDS-NIPKSNNFENPKLYFLQCNIPKYLAKVKNENGKCPKLVKQFLLDILVYNENGENKYSDDAYVRSLIENVVKVALNEYKDKAYMEKVKTQLLRYENLVNWLSSYESLIKTTIMYAKYKLHKVGAYDFTELTGMIMHTLTLGINNGDISRESFQNEFLMVLKIMLLEGGLKNKDALVLFTEILCFHEDSYIRDKSVDVLSECVNLVVMDGSLDTISDDIKSSVQSVHNEVKNIKSEDDIELFLSGHYVDDMKIKIEKIGRQNISGLIQICRDMFKGYSPLKILLWDVLNLPVLSLYQRKQIHDLVRVMYTLIN--------------------------------------SFVVRLETPRERRLVAKMNSNEEGKLDIVIKRESILKVHIKKEVTSTVEAPKKANKIKISLKGDKP-------------------------------------VRKVEKQIVKPKVTSKQRKVKSHVNRMGSLPLRFVKIQQQPRVMVHLSSVPYSQFVQIT-----------------KVTSRSFMVKIRTKNDAKN-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * ::::*: :.: :.: :.: * . : *.* **. : ::.*: * * ::: * : ** ... * : :: . .:.:* *::*.. :: : : : *::.: :** *::* . : . .*: *.**** : .**.***:* : :. .:: * . *: **. : : *... :*. *:* *: * : : * ** . : :: :: ::**.: : **::*:. **: . :*::.* ...**:. :**:: : :: ::*:*: *: * * **: *: :* :* * *: :: : :* : : * . .. . . : :: ** :::::::.*: :.: *. : .: ::: * : *. ..: ::.:*: .* : : ***** .:** *:* . * .* * .: : ::* **: ::* ::*:.. * ** ::* ** :*: ::.* :... . . :. :... ***:*.:: : .: ::*.*: :. :** : *: ** ::* :. . * .:: *: :* *. .*:* . . : * : .:* :* . :* * *** . : **** :* :* :: :. ** * *::*:: **:* .*:::* * ::: ** : . :: :.* . *: : : : :* .. : * . * : ..: : :. : :.:: :..: .: : : ::. . . . : .: .: . : : * : :. * ::: :. * * . :: : : .. : :. : :: .. : * ::: : * . .: : . : .. : ", "identical_positions": 163, "similar_positions": 355, "identity": "10.57%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3208", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60502-1", "uniprot_id": "OGA_HUMAN", "id": "O60502-1", "name": "Protein O-GlcNAcase", "aln": "MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELN---TYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSD---EDIETDVLYSPQMALKLALTEWLQEFGVP--------------------------------------HQYSSRQVAHSG------------------------------------AKASVVDGTPLVAAPSLNATTVVTT-VYQEPIMS-----QGAALSGEPTTLTKEEE----KKQPDEEPMDMVVE-KQEETDH-KNDNQILSEIVEAKMAEELKPMDTDK-------------------ESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKG--------KDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLG------------------CRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDG---------VGLPFQSQ-PDLIGDKLVGGLLSLSLDYCFVLEDEDG-ICGYALGTVDVTPFIKKCKISWIPFMQEKYTK-----PNGDKELSEAEKIMLSFHEEQ-----EVLPETFLANFPSLIKMDIHKKVT--DPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9EQQ9-1", "uniprot_id": "OGA_MOUSE", "id": "Q9EQQ9-1", "name": "Protein O-GlcNAcase", "aln": "MVQKESQAALEERESERNANPAAASGASLEQSVAPAPGEDNPSGAGAAAVVGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELN---TYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSD---EDIETDVLYSPQMALKLALTEWLQEFGVP--------------------------------------HQYSSRQVAHSG------------------------------------AKTSVVDGTPLVAAPSLNATTVVTT-VYQEPIMS-----QGAALSGEPSVLTKEEE----KKQPDEEPMDMVVE-KQEEAEH-KNDNQILTEIVEAKMAEELRPMDTDK-------------------ESMAESKSPEMSMQEDCIPDVAPMQTDEQTQKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKG--------KDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLG------------------CRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMYDDG---------VGFPFQSQ-PDLIGDKLVGGLLSLSLDYCFVLEDEDG-ICGYALGTVDVTPFIKKCKISWIPFMQEKYTK-----PNGDKELSEAEKIMLSFHEEQ-----EVLPETFLANFPSLIKMDIHKKVT--DPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2R8RWC3-1", "uniprot_id": "A0A2R8RWC3_DANRE", "id": "A0A2R8RWC3-1", "name": "Protein O-GlcNAcase", "aln": "MVQKDK--IIESSQPEVEVIPVPVEAVADTQCPVDEP-----------TIEIERTGRRKFITGVVEGFYGRPWTMEQRKELFRRQQKWGLN---TYLYAPKDDYKHRMFWREMYSVEEAEQLTTLISAAKEYGIEFIYAISPGLDITFSNQKEVSTLKRKLDQVTHFGCKSFALLFDDIDHNMCPADKEVFSSFAHAQVSVTNEIFQYLGEPEIFLFCPTEYCGTFCYPNVSQSPYLRTIGEKLLPGIEVLWTGPKVVSKDITVESIEEVTKILRRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFESNFVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSD---EELETDILYSPQIALKLALTEWLSEFGVP--------------------------------------HQYNSRQVPHSG------------------------------------TKSTTMD-VPTLAASTLVTSTTVTT-VFQQPIMS-----PVLPLSDEPHVLGKEEEEEVEKKESDEEPMEMVVE-KHDEVEDTKNVNQILTEIVKAKMTEDLKPMDTDK-------------------ESLTESKSPEMSIQEDSGSDIAPMQTDDQLNKEVFVPGPNEKPLFITEALTLEDLTLLAELFYLPYEHGPKSVQMLKEFNWLRANSNYVSVNSKA--------KDPEKVTEWQSRAENFEEMCCSVMQMFTRLSNSANRTILYDLYPYIWDIKSIISMVKSFVQWLDGRILGTSFYCYWTDSARWCRSQSSAQFLSGDQEPWAFRGGLAGEFQRLLPIDGANDLFYQPPPSMPTSKIYTIRPYFAKDESAIYKICKEMFTESC--------EGISFSDESPDLIGDRLVGGFLTLSPDYGFVLEDEEG-VCGYAMGTVDVKPFVKKCKLSWIPFMQEKYIK-----PDAEKDLSEAEKMMLSFHEEE-----DGLPESFLRNFPSLIKVDIHAKVT--DPSVAKSMMGCLLSSLKANGSHGAFCEVRQIDKRMLDFYSKLGCFEVAKMEGFPKDIIIMGRSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDC9-1", "uniprot_id": "Q9VDC9_DROME", "id": "Q9VDC9-1", "name": "protein O-GlcNAcase", "aln": "--------MADEAGSQAD-------------------------------------GKRQFICGVIEGFYGRPWTTEQRKDLFRKLKSMGMGSSPSYMYAPKDDYKHRAYWRELYTVEEADHLSSLIAAAKEAGITFYYALSPGLDMTYSSPKEIATLKRKLDQVAQFGCEAYALLFDDIESELSKADKEVFQTFANAHVSVTNEIYTHLGSP-RFLFCPTQYCASRAVPTVQESEYLNTLGSKLNNEIDILWTGDKVISKNISLESIQEITEVLRRPPCIWDNLHANDYDQKRIFMGPYSGRSPELIPHLRGVMTNPNCEFYGNFVAIHSLAFWSRCSLD---------SKVNSSLSADIKLETENDDDLPAEFLSKNVYHPRLALKNAITEWLPEFFMKKEAWGPITKPQPQVQMVMPIIPIIPSINTCMSLTTTTTTSTSSRTVPPTVNTTQLQALADVCVVTSSLTPISNPVMNSLVSPTKVITNDDIINPIPTTAASNIELPKKIPISVVPVPIMETKSVEASVELALDNAVFDDNEIEPNSDSVKERLELEVNLEGKQEPVANLSVDTMLDDDSLSPLSGVVNEPMECSSSITSQVSPREEEAIKVVADDVLMESVNDVHSMHVESGTSSPISNAEMREETEAQSDRTNDNNTIEGEGITVDDLVLLCDLFYLPFEHGSRGHKLLVEFNWLKGNANVILQDRSAGGGGDAIKSDKPEVSEWHQRREQFDQLCSAVVELLIKIANCPNKEICHELYSYMWDISGALSLLNCYVKWLALGHFPQNTSSYTEGSYTWFSKGWKEAFMSGDQEPWVFRGGLIADLQRLMPVDSGNDLFVYKLPEQPTANYYLLRPYCNSDEQQVNDLCTRLYLQWRGELDGGRHIPFPLPANVPNIVADGLIGGYLTLSPQLCIVAYDESNRIIGYSCAALDVNIFRRNLELCWYTELREKYSRDICPLEGGEEVVQLVTSLVESYHDSSGNGALDQCPVEVSGSFPAVLISGTLREAEERDSGITKRMLTVLLAALRANGCFGAHVRVPQQDVAQVNFYSRIGFVDVYREEAT--KCIYMGRRF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .: . * *:*: **:********. ****:***: :. :. :*:********** :***:*:****::* :**:**:* * * **:*****:*:*. **::*********::***.::*******: ::. ******.:**:*:**:****: :**.* ******:**.: . *.*.:* **.*:*.** *::**** **:**:*.:***:*::::::*.* ****:*********:*:***.***.****:*:**:******* .*:****:** * :..:: .. :*::* :****.*..* :: :. :* *::*** *:**** ** : . .** *. : :: :: * **..: .. :. * ***. *: : .: .:* .. :. ::: :* *:: . . . . : : :.. .**: .. : : ** . *:: :. .. . ::: : :.* .*:: * :*::** **.:*****:***.:. ::* **:**:.*:. : : .. .* :: **:.* :*:::* *: :: :::*..*: * :::*.*:***.. :*:::.:*:** . . *: ******.***** .::***:*:*..**** * **:: * :*** .** : .:* .:: : :.: : *:::.* *:** *:** : :* **.. : **: .::**. * :: ::.* . ::*** : ..:: :. . .:: *:*:.. : * . .**::: . :. *..::* *: **::*:***. **. .* * ::***::* .:: : *. . : :** :", "identical_positions": 326, "similar_positions": 320, "identity": "30.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-321", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q641Z4-1", "uniprot_id": "CDK9_RAT", "id": "Q641Z4-1", "name": "Cyclin-dependent kinase 9", "aln": "-----------------------------------------MAKQYDSVECPFCDEVTKYEKLAKIGQGTFGEVFKAKHRQTGQK-VALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTK-----ASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFS--------LAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVWPNVDK-YELFEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPS---------DLKGMLSTHLTSMFEYLAP----------------------------PRRKGSQITQQSTNQSRNPATTNQTEFERVF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J95-1", "uniprot_id": "CDK9_MOUSE", "id": "Q99J95-1", "name": "Cyclin-dependent kinase 9", "aln": "-----------------------------------------MAKQYDSVECPFCDEVTKYEKLAKIGQGTFGEVFKAKHRQTGQK-VALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTK-----ASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFS--------LAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVWPNVDK-YELFEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPS---------DLKGMLSTHLTSMFEYLAP----------------------------PRRKGSQITQQSTNQSRNPATTNQTEFERVF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50750-1", "uniprot_id": "CDK9_HUMAN", "id": "P50750-1", "name": "Cyclin-dependent kinase 9", "aln": "-----------------------------------------MAKQYDSVECPFCDEVSKYEKLAKIGQGTFGEVFKARHRKTGQK-VALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTK-----ASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFS--------LAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVWPNVDN-YELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPS---------DLKGMLSTHLTSMFEYLAP----------------------------PRRKGSQITQQSTNQSRNPATTNQTEFERVF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXE8-1", "uniprot_id": "CDK9_DANRE", "id": "Q7SXE8-1", "name": "Cyclin-dependent kinase 9", "aln": "-----------------------------------------MSKYYDGVEFPFCDEFSKYEKLAKIGQGTFGEVFKAKHRQTGKK-VALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKG---EATQFNRYKGSIYLVFDFCEHDLAGLLSNANVKFTLAEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFS--------LAKNSQGNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLTLISQLCGSITPEVWPGVDKKYELYQKMELPKGQKRKVKDRLKAYVKDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPS---------DLKNMLSTHNTSMFEYLAP----------------------------PRRRG-HMPQQPANQNRNPATTSQSEFDRVF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O17432-1", "uniprot_id": "O17432_DROME", "id": "O17432-1", "name": "", "aln": "----------MAHMSHMLQQPSGSTPSNVGSSSSRTMSLMEKQKYIEDYDFPYCDESNKYEKVAKIGQGTFGEVFKAREKKGNKKFVAMKKVLMDNEKEGFPITALREIRILQLLKHENVVNLIEICRTK-----ATATNGYRSTFYLVFDFCEHDLAGLLSNMNVKFSLGEIKKVMQQLLNGLYYIHSNKILHRDMKAANVLITKHGILKLADFGLARAFS--------IPKNESKNRYTNRVVTLWYRPPELLLGDRNYGPPVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQLCGSFTPDVWPGVEE-LELYKSIELPKNQKRRVKERLRPYVKDQTGCDLLDKLLTLDPKKRIDADTALNHDFFWTDPMPS---------DLSKMLSQHLQSMFEYLAQ----------------------------PRRSNQMRNYHQQLTTMNQKPQDNSMIDRVW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23293-1", "uniprot_id": "BUR1_YEAST", "id": "P23293-1", "name": "Serine/threonine-protein kinase BUR1", "aln": "MSDNGSPAVLPKTEFNKYKIGKVKSTPAIQRDAKTNLTYIKLRKRSSEKVYGCTVFQNHYREDEKLGQGTFGEVYKGIHLETQRQ-VAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLGTPTEEDWAVARY---LPGAELTTTNYKPTLRERFGKYLSET-GLDFLGQLLALDPYKRLTAMSAKHHPWFKEDPLPSEKITLPTEESHEADIKRYKEEMHQSLSQRVPTAPRGHIVEKGESPVVKNLGAIPRGPKKDDASFLPPSKNVLAKPPPSKIRELHQNPRPYHVNSGYAKTAIPPPAAPAGVNRYGPNNSSRNNRFSGNSTAPNNSRNPVNRFHPETNVSSKYNKVPLPLGPQSRYQGNSNESRYKNSPNDSRYHNPRYVNKPETNFNRQPQKYSRQESNAPINKNYNPSNGSRNMAGDHHQGSRPSHPQFPISPSQGQHQLTSKPIEKKNGSFKDERAKPDESKEFQNSDIADLY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .:*.: *:********:*. . : :: **:**:::. **: ***** *** **: *:*:*:::***: : : . : ::*::: : **:*:* * ::: : :**.:* :*:** *** *::***:*:**:** :.*:********** : . :**. *** ***.***:**:::* ..:*:**.**::**:: :.**:**:*: .* .* :* *: * : *. . * .. * :::*: *: : . *::.:**.*** :*: : * :* :* **:** . . :. : .*.: *: *:: . : . . :.: ", "identical_positions": 122, "similar_positions": 122, "identity": "18.43%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3217", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JXY3-1", "uniprot_id": "A0A0G2JXY3_RAT", "id": "A0A0G2JXY3-1", "name": "", "aln": "-----------------MPSPVSPTEQQSPIGQYSSALLGREQQGWD---------------------------HKTNEKCFLETVFFYLLDTRSLEDLQLLLTEEESWKHFVEGVGLSREEEDALQEALAEIFEDSDGEEGDKLQRDLQGKKERGTVRCLGDGSSCSQLSRYRKEEDALKEALGGNAADSDTEDEDQLQND---KERFLEAYPQVRQELEERIKKLHALADKVDKVHRDCTISQVVASSSSAVSGVLTILGLALAPVTAGVSLALSATGMGLGAAAAVTSVSTIIVEKVSLASAEAEASKLVLTNKVTMNGMKEVLEQSGPRLLSVSTNSFKDLKNIKTSIQAIKLTKAN--PRLTTNAKRLMTTGKISARKTRQVQKAFGGTALAMTKEARIMGATTAGLFLLMDVVRLVEDSKHLHEG---AKSVSAAELRQQAQDLEQKLQELNQVHDSLTQ---------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2K7F8-1", "uniprot_id": "A0A0G2K7F8_RAT", "id": "A0A0G2K7F8-1", "name": "", "aln": "-------------------------------------------MGTG---------------------------HAHEKKCFLETVFFYLLDTRSLEDLQLLLTEEESWRHFVAGVGLSREEEDALREALAEIFEDSDGEEEDKLQSDPQDKKERGTVRCLGDESSCCEWESPTKEEDALREALGGNTADSDTEDEDQLQND---KERFLEAYPQVRLELEKHIKKLHALADKVDKVHRDCTVSQVVASSSSAVSGVLTILGLALAPVTAGVSLALSATGMGLGAAAAVTSVSTSIVEKVSLASAEAEASKLVPT-KDTMNRMKEVLEQSGPRLASLSTNSIQNIQAIQKNMNAIQLAKAN--PHLATNAKRLMTTGKTSTQTTGQVQKAFGGTALAMTKEARIIGAATVGLFLLMDVVRLVEDSKHLHEG---AKSVSAAELRRQARDLEQKLQELNQVHDSLTQ---------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AQP7-1", "uniprot_id": "B1AQP7_MOUSE", "id": "B1AQP7-1", "name": "", "aln": "-------------------------------------------MGT------------------------------PDRECFIETVAEYLLDVISTEDLQLLLTEEETWKHFVAEVDLSREEETALREALAEIFSDPDGEDEDELQNDLQDKNER-------------------KEEDALSEALGETVADTDAEDEEEIQNDPWHKERFLDAYPRVKLELEESIRMLHALADKVDKVHRDCTISRVVASSSSAVSGVLTILGLSLAPVTAGVSLALSATGLGLGAAAAVTSVSTSIVEKVSVVFAEAKASKLVPTNKDTMKGMKEVLDQSGPRLLFLSMNSFKKLKNIKNNIHAIKLTKAN--PSLVTNAKRLMTTGKTSTETTKQVKEAFGGTALAMTKGARIMGAATTGFFLLLDIVSLVGDSKHLHEG---AKAESAAELRHQAQDLEQKLQELIRVHDSLIQ---------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RBH1-1", "uniprot_id": "M0RBH1_RAT", "id": "M0RBH1-1", "name": "", "aln": "----------------------------------------MDPSDGE---------------------------DSPASRTFIEEATEYLQHTSGRDDLKLLLTEDGAWEAFVAEAELSRADADTLRDALNALTANMAEEDQNRLQHDLQD------------------------------------------------------VERFIDVFPQVKLELERHVRKLRTLADKVDKVHRDCTISKVVAGSTSTVSGVLTLLGLALVPVTAGVSLVLLATGMGLGAAAAVTSVSTGIVDYTSKSSAQTEASHLVSTSMVKVKMAAEAVVYSGPQVFSLSESCCRVLRCIEQSVYAIKLTKAN--PALAASVKRLMTVGSISAQSDKHVKKAFKGTALAMSRRTRIMGIATAGVSLIGDVISLVKESKNLYKG---AKAKSAEELRQQARELEEKLEVLVQIYDGLQSGSTQSS---------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F7F6E7-1", "uniprot_id": "F7F6E7_RAT", "id": "F7F6E7-1", "name": "", "aln": "----------------------------------------------D---------------------------NQVLRKQFIQDVTEYLQDTVSKKDLQLLLTKDEAWKVFVAEAELSRDEEASLHEALKLLLKLPTWEDKVRLQKELQD------------------------------------------------------RKKFVEAFPQLKRKLQENIRKLRALADHLDQVHKGCTISNVVTNSTSAASGVLSILGLALAPVTAGGSLLLSATGLGLGTVATVTGAATEIVEQTNKWLDEAEARRLLSDTMDTLN-TALVLGQKALKLSKKAYDVIKQLKSLGQHIRAIRVARAN--PRLLADAKRLMTSGRLSAPRASQVQNAFEGTALAMTKKARIRGVATAGVFLAMDVYFLVRDSMDLCDG---AKSESGNKLRALAQELEEKLKEVAQIYKSLLVPY-------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95236-1", "uniprot_id": "APOL3_HUMAN", "id": "O95236-1", "name": "Apolipoprotein L3", "aln": "MGLGQGWGWEASCFACLIRSCCQVVTFTFPFGFQGISQ---SLENVSGYYADARLEVGSTQLRTAGSCSHSFKRSFLEKKRFTEEATKYFRERVSPVHLQILLTNNEAWKRFVTAAELPRDEADALYEALKKLRTYAAIEDEYVQQKDEQF------------------------------------------------------REWFLKEFPQVKRKIQESIEKLRALANGIEEVHRGCTISNVVSSSTGAASGIMSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASRLTATSIDRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARA--------RARLPVTTWRISAGSGGQAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEG---AKSASAEELRRQAQELEENLMELTQIYQRLNPCHTH-----------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BPW4-1", "uniprot_id": "APOL4_HUMAN", "id": "Q9BPW4-1", "name": "Apolipoprotein L4", "aln": "--------MEGAALLKIFVVCIWVQ------------------QNHPGWTVAG---------------------QFQEKKRFTEEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAELPREEADALYEALKNLTPYVAIEDKDMQQKEQQF------------------------------------------------------REWFLKEFPQIRWKIQESIERLRVIANEIEKVHRGCVIANVVSGST----GILSVIGVMLAPFTAGLSLSITAAGVGLGIASATAGIASSIVENTYTRSAELTASRLTATSTDQLEALRDILRDITPNVLSFALDFDEATKMIANDVHTLRRSKA--------TVGRPLIAWRYVPINVVETLRTRGAPTRIVRKVARNLGKATSGVLVVLDVVNLVQDSLDLHKG---AKSESAESLRQWAQELEENLNELTHIHQSLKAG--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O14791-1", "uniprot_id": "APOL1_HUMAN", "id": "O14791-1", "name": "Apolipoprotein L1", "aln": "--------MEGAALLRVSVLCIWMSALFLGVGVRAEEAGARVQQNVPSGTDTGDPQSKPLGDWAAG-------TMDPESSIFIEDAIKYFKEKVSTQNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQY------------------------------------------------------RNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLGENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEG---AKSETAEELKKVAQELEEKLNILNNNYKILQADQEL-----------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9PUZ0-1", "uniprot_id": "E9PUZ0_MOUSE", "id": "E9PUZ0-1", "name": "", "aln": "----------------MDWNEISED-------------------------------------------------IRKVECRTFEKVIDNATEDLI-TDLRSLITEDGAWNGFVEAVELSSEEGEALRDALKERLAQDPTDENDRPQREQQK-------------------------------------------------------ERFLREFPQLKKKLEDHIRKLRDLADKFDQVHKDCTISNVVSTSASAASGVLALLGLVLSTVTAGASLALSASSVALGATSSVSSFTTTVVEDSMTLSYESEARNLIGASMNVLEEILSIMPKITCKFYNTVADLVKAFKTLKGQIQTIR-------------RARSISRRGAQARNLTSTGRSSGQGVSQMTRGARIRAGVFTSVFLGWDVYDLVTKQRICMMGEKQSQVEHCGTWLASWRRTFRNLSRSTMLCSQTCLSDALP----------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PZG0-1", "uniprot_id": "E9PZG0_MOUSE", "id": "E9PZG0-1", "name": "", "aln": "----------------MDWNEILEG-------------------------------------------------IKKVERRIVEKAIDNFTEKFLRTDLRSLITEDGAWNGFVEAAELSREEGEALRDALKERLAQDPTDENDRPQREQQK-------------------------------------------------------ERFLREFPQLKKKLEDHIRKLRELADKFDQVHKDCTISNVVSTSASAASGVLALLGLALSTVTAGASLALSASSVALGATSSVSSFTTTAVEESMRLSYESEARNLIGASMNVLEEILKIMPKITYKFYSTVADLAEAFKTLKDQIQTIR-------------RARSISRRGAQARNLPSTGRSSGQVVPQMTRGARFQKGVFTSVLLGWDVYDLVNQSKDLYYG---AKTKSGGALRDLARKLEENLQEFEQKC--KALQSDLPQ---------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3X9K7-1", "uniprot_id": "G3X9K7_MOUSE", "id": "G3X9K7-1", "name": "", "aln": "----------------MARAWCSTD-------------------------------------------------LKQGVARSVDGVADIVTEKFLKTDLRSLITEDGAWKAFEEAAELSSEEGAILRDALKESLAQEPSDENDGPERKQQN-------------------------------------------------------ERFLREFPELKKKLEDHIRKLRDLADHLDQVHKDCTISNVVSTFASAISGAMGLLALGLVPFTEGVSLLLSAASVGLGETASVTGLTTTVVEESMRLSDESEASRLVRASMNVFEEIVKIMSKITFKLLFTAVGLVPAVKILRDHIRAMR-------------RARIIIFPREEARNLTSSERSSVQGVLPMTRGARLRAVGFTSLFLAWDVYDFVKQSKDLYNG---AKTESAGALRELAHKLEEKLQVFEQIY--KALQSDLPH---------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BWW8-1", "uniprot_id": "APOL6_HUMAN", "id": "Q9BWW8-1", "name": "Apolipoprotein L6", "aln": "-------------------------------------------------------------------------------------------------------MDNQAERESEAGVGLQRDEDDAPLCEDVELQDG----------------------------------------------------------------DLSPEEKIFLREFPRLKEDLKGNIDKLRALADDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAPATGGGSLLLSTAGQGLATAAGVTSIVSGTLERSKNKEAQARAEDILPTYDQEDREDEEEKADYVTAAGKIIYNLRNTLKYAKKNVRAFWKLRAN--PRLANATKRLLTTGQVSSRSRVQVQKAFAGTTLAMTKNARVLGGVMSAFSLGYDLATLSKEWKHLKEG---ARTKFAEELRAKALELERKLTELTQLYKSLQQKVRSRARGVGKDLTGTCETEAYWKELREHVWMWLWLCVCLCVCVYVQFT--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7ZC55-1", "uniprot_id": "B7ZC55_MOUSE", "id": "B7ZC55-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------MALVQTPTPSHQTEEDYEADAELLRDKDDSPL--DVED------------------------------------------------------------------------DVLFLKQFPSWRKKEKKRIRTLYAIADHIDESHQKATKIKVVTTSASVASGVLSLLGLALATTTAGGSLVLTAVGHGLGAVAGVTEIVTNVRKNSRNKRALAQVNSIMPNSDQELEGVKGEKTTFVTAAGDLVYKCGNAWDNIKKHLRALQLTRTQ--PHVTSAAKKLMTAGHVSARSGRQVQKAFGGTALAMTKNALRMGRAAAALSLGQDIYTLWEDWKDLKAA---NPTELAEELRARAAERERVLAEHTCRYRKLQVRVG---------FYLLLLLFVFLLELRTDPRALFLLGKHSTTELNL-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BWW9-1", "uniprot_id": "APOL5_HUMAN", "id": "Q9BWW9-1", "name": "Apolipoprotein L5", "aln": "-----------------------------------------------------------------MPCGKQGNLQVPGSKVLPGLGEGCKEMWLRKVIYGGEVWGKSPEPEFPSLVNLCQSWKINNLMSTVHSDEAGMLSYFLFEELMRCDKDSM------------------------------------------PDGNLSEEEKLFLSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVTAGGSLMLSATGTGLGAAAAITNIVTNVLENRSNSAARDKASRLGP-LTTSHEAFGGINWSEIEAAGFCVNKCVKAIQGIKD-LHAYQMAKSN--SGFMAMVKNFVAKRHIPFWTARGVQRAFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDG---ARTETAEELRALAKKLEQELDRLTQHHRHLPQKASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVALRTPKRTVSAPRMLGHQPAPPAPARKGRQAPGRHRQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6B959-1", "uniprot_id": "APLD1_RAT", "id": "Q6B959-1", "name": "Apolipoprotein L domain-containing protein 1", "aln": "---------------------------------------------------------------------------------------------------------------MEKWTAWEPQGADALR--------------------------------------------------------------------------------RFQGLLLDRRGRLHCQVLRLREVARRLERLRRRSLAANVAGSSLSAAGALAAIVGLSLSPVTLGASLVASAVGLGVATAGGAVTITSDLSLIFCNSREVRRVQEIAATCQDQMRELLSCLEFFCQWQGRGDRQLLQSGR-----------------------------DASMALYNSVYFIVFFGSRGFLIPR--RAEGATKVSQAVLKAKIQKLSESLESCTG---ALDELSEQLESRVQLCTKAGRGHNLRNSPDLDAALFF----------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q0X2-1", "uniprot_id": "E9Q0X2_MOUSE", "id": "E9Q0X2-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------MEKRAAWEPQGADALR--------------------------------------------------------------------------------RFQGLLLDRRGRLHSQVLRLREVARRLERLRRRSLAANVAGSSLSAAGALAAIVGLSLSPVTLGASLVASAVGLGVATAGGAVTITSDLSLIFCNSREVRRVQEIAATCQDQMRELLSCLEFFCQWQGRRDRQLLQSGR-----------------------------DASMALYNSVYFIVFFGSRGFLIPR--RAEGATKVSQAVLKAKIQKLSESLESCTG---ALDELSEQLESRVQLCTKAGRGHNLRISTDLDAALFF----------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96LR9-1", "uniprot_id": "APLD1_HUMAN", "id": "Q96LR9-1", "name": "Apolipoprotein L domain-containing protein 1", "aln": "------------------------------------------------------------------------------MFRAPCHRLRARGTRKARAGAWRGCTFPCLGKGMERPAAREPHGPDALR--------------------------------------------------------------------------------RFQGLLLDRRGRLHGQVLRLREVARRLERLRRRSLVANVAGSSLSATGALAAIVGLSLSPVTLGTSLLVSAVGLGVATAGGAVTITSDLSLIFCNSRELRRVQEIAATCQDQMREILSCLEFFCRWQGCGDRQLLQCGR-----------------------------NASIALYNSVYFIVFFGSRGFLIPR--RAEGDTKVSQAVLKAKIQKLAESLESCTG---ALDELSEQLESRVQLCTKSSRGHDLKISADQRAGLFF----------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BJ26-1", "uniprot_id": "A0A8M2BJ26_DANRE", "id": "A0A8M2BJ26-1", "name": "", "aln": "-----MDSEVFKIEENDGEPSTSKQGVEKTQQFLEPSEKPDDKESKLMQDMGSGLNPEELADVAGQPVLGQVDNNEVLEKKVAETPREAREEENPTQKGQKKKPKNPFMPQIAAKNKTTQKKNEDQNIGAGSVVAETKDHKKTLMEWLDDFRLSETQREDEEDLEGLMDWWNTVEQWEDMPKNDNMTEKEEAKAFAVTADKVQKGIRVFNKLFSERAEGLWQHVIDLHAIADGLDRFNKKTKIAQITGGSTSAVGGVATITGLILAPFTMGTSLIVTAVGLGVAMAGGLTSASAGITSTVNNSLDRKKVERIVGDYQAKMGDLNKCMKFIKQGITNLRKFNLNKMKKHAYNRDFPCFDNVY---EDGAMAGKAILTNANEIMRVMQIANVAGTTAARAVQIASISTGVLTGLFVGMDIYFVAKDSHELKNG---AKSEFAAKIREVAEQLHEGLMELNIIRDELRMTTTVKEDQTS-----------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * :* .: .. :. . : .: * . * * ** . :. .. : . : . . : . . . ", "identical_positions": 8, "similar_positions": 27, "identity": "1.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-322", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2T1-1", "uniprot_id": "A0A0G2K2T1_RAT", "id": "A0A0G2K2T1-1", "name": "", "aln": "METNHPDQLSVE-QPNPPGDSSPLN-QNVPGKQDVQQSSTSGQAAEQEASPHPEKGDHDISEELSRQLEDIINMYGSAASPTGKEGTSETKEQPQNTEAPDNEDGDYEETTEETDREPTAPEEPATVKGPVSNKEQKLEKKILKGLGKEANLLMQNLNKLQAPEEKLDFLFKKYAELLDEHRTEQKKLKLLLKQQAQTQREKDQLQSEHNRAILARSKLESLCRELQRHNKTLKEETLQRAREEEEKRKEITSHFQSTLTDIQTQIEQQSERNMKLCQENTELAEKLKSIIDQYELREEHLDKIFKHRELQQKLVDAKLEEAQELMQEAEERHRREKEYVFILLLLNQAAEWKLQAKVLKEQETVLQAQLTLYSGRFEEFQSTLTKSNEVFATFKQEMDNTTKKMKKLEKDTATWKARFENCNKALLDMIEEKALRAKEYECFVMKIQRLENLCRALQEERKELYKKIRDAKMSEK----------------------------------------------------EDQVQHTSDEEPESKVS--EDKQMDVEAANGVQNAVKNLATAFAILHHPEFTPDQSRERQPAVNGPP-------------GGSDLTHQHTEPAHLNHPNPSSVSGSPQPP--------------------VGSQAGSEGGCEAAP---------------------------------------------APTACCTPA--EAELQSQGLSAGNPPDPKPQKP------------EAKASGQVPLSPAQGSLAVVEAKCDISPSPESE--------RDPAVVPGCESKEHPP-PEVPDIPLGPNTG-LPR-EPDACLNGVE------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VBT1-1", "uniprot_id": "TXLNB_MOUSE", "id": "Q8VBT1-1", "name": "Beta-taxilin", "aln": "MEINHPDQLSVE-HPTPPGDSSSLN-QNGPGKQDGERCSTSGQAPEQEGSLHPEKGAHDVAEELSRQLEDIISTYGSAASPRGKESTSETKEQPPNTEAPDNEDVDYEETTEEIDREPTAPEEPAAAKEPVSNKEQKLEKKILKGLGKEANLLMQNLNKLQAPEEKLDFLFKKYTELLDEHRTEQKKLKLLLKQQAQTQREKDQLQSEHNRAVLARSKLESLCRELQRHNKTLKEETLQRAREEEEKRKEITSHFQTTLTDIQTQIEQQSERNMKLCQENTELAEKLKSIIDQYELREEHLDKIFKHRELQQKLVDAKLEEAQELMQEAEERHRREKEY-----LLNQAAEWKLQAKVLKEQETVLQAQLTLYSGRFEEFQSTLTKSNEVFATFKQEMDKTTKKMKKLEKDTATWKARFENCNKALLDMIEEKALRAKEYECFVMKIQRLENLCRALQEERKELYKKIREAKMSEK----------------------------------------------------EDQVQRTSEEEPEPSVS--ENEEVDAEEANSFQKAVENLATAFTILHHPEFTPDQPTERQLAVNGPQ-------------SGSDVTHQHPETARLNHPSLPADSGSPRPP--------------------VGAQAVAEGVCEATP---------------------------------------------APTASCTPA--EAELQSQGLPAENTPGPKPHKP------------EANTSGQAPLSPAQGSLSVVEAKYDISPSPESE--------GDSAVVPGCESREQPP-PEVTDIPVGPSTG-LPR-EPDACLNGVD------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N3L3-1", "uniprot_id": "TXLNB_HUMAN", "id": "Q8N3L3-1", "name": "Beta-taxilin", "aln": "MEANHSEQLSAERQSTPPGDSSSLPSHNGLEKEDGQDSPTPVQPPEKEASVHP-----DISEELNRQLEDIINTYGSAASTAGKEGSARASEQPENAESPDNEDGDCEETTEEAGREPVASGEPPTVKEPVSNKEQKLEKKILKGLGKEANLLMQNLNKLQTPEEKFDFLFKKYAELLDEHRTEQKKLKLLQKKQVQIQKEKDQLQGEHSRAILARSKLESLCRELQRHNKTLKEEALQRAREEEEKRKEITSHFQSTLTDIQGQIEQQSERNMKLCQENTELAEKLKSIIDQYELREEHLDKIFKHRELQQKLVDAKLEQAQEMMKEAEERHKREKEY-----LLNQAAEWKLQAKVLKEQETVLQAQLTLYSGRFEEFQSTLTKSNEVFATFKQEMDKTTKKMKKLEKDTATWKARFENCNKALLDMIEEKALRAKEYECFVMKIGRLENLCRALQEERNELHKKIRDAEISEK----------------------------------------------------DDQSQHNSDEEPESNVS--VDQEIDAEEVNSVQTAVKNLATAFMIIHHPESTPHQSKETQPEIGSSQ-------------ESADAALKEPEQPPLIP---SRDSESPLPP--------------------LTPQAEAEGGSDAEP---------------------------------------------PSKASNSPAGLGAETQCEGLPVGAQADQASWKP------------EAEASGQAPQAPTEASLQKMEADVPAPACAAEE--------HVAAMVPACEPSRQPPRAAAEELPVGASAGPQPRNVADTNLEGVD------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B617-1", "uniprot_id": "A0ACD6B617_DANRE", "id": "A0ACD6B617-1", "name": "", "aln": "-MMEGSDQISEN------------------VNEQVNES--------EEQQVDP-------MEDFSRQLEDIINTYGSASSLMQEQISILESEEGKDEEAKADEESESKEVAAGAD------------------KEQNTEKKLLKGLGKEAAFLLQSLNKLGSPEEKVEMVLKKYSELVDEHRTEKKQLERFQQRQGLLVKQRDQLQFEHSRAILARSKLETLCRELQRHNRTLKEESLQRLREDEMKRKEITTHFQSTLVDIQSQIEQHSNRNNKLCKENSELAGKLKTIIEQYERREESLEKIFKHRDLQQKLSDAKLEEANMLLTQAEEKHKREKEY-----LLKEAIDKTKKYCTLREQELQMKKQLVLYSQKFDDFQNTLAKSNEIYVTFKQEMDKMTKKMKKLEKESTTWKTRFESCNKALVEMIDERSEKGKEFELFTLKIDRLETLCRALQDERKSLYAKIKEIRFPEKMTAAPVVDIPPIDELPELVQTPNPMLTAEMEKLRAEQVRLQDFAASLLSPVPDDAGESDSEDEEKEKDSPAIPEAQSIKQADQLESTQEQSSTTKVIEEKPTATKSEMDSKLPEASQLESIKPIDQLKSTQEESSTIKVTITEEKPTSPETTKPDTESKIPPEPFPKDTKPVDKLESTEEKSITEDLKPEVAVNAVKPLVPTILEDAKPEMESKLPQETLKLVDKPKSTQVESSTTEKQNTEKPSVPTIPEPTKPEMESKLPQEAGKPESAKEEPRQEEVKKAEDTVKQESAQPKPVVKEESKDEAVKPEVPEPEPPKQEPLKEEDTQKATAVSEGAKASAIKPKAPKSQDAKAKASKAQPKKQTPAKKKGAAKGPNKS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBL3-1", "uniprot_id": "Q9VBL3_DROME", "id": "Q9VBL3-1", "name": "Alpha-taxilin", "aln": "---------------------------------------------MEKLS-----------------------------------------------------------------------------------KAKKVAREEKQRDQKLEELVMKSLDECPSAEEKVKLLLQRHVDSEKNVSRLTAELRVLQRQMESQQREKEQVQRDLNKSVLMRDKLQEVCREQQRIIKSVKNESLLQIKVEEERRKESQTKFQSSLNDVQKSLAKNNEENIKLRDYNIEMTKKLKLLAEQYQTREQHLEKLNEQVQLEAQLHQAKLQKCQVEAAMEKEILSKENQIG-----LEKLMQAQRAIKDLTDREHQLKEQLNIYTAKYDDFQQSLQKSNEVFGSYKVELEKMSKHTKKIEKEALGWRQKYEKANAMVIDLATEKSLQTQHSERLQKQIQQLQKLLRALQLERTTLHKCLRDHEIEIP--------------------------------------------------ALPQLPPEPEPVNVKPVSAENVKMEMMSRNCAELKQTLANLQNQMKLLTTNESKTSIEEKKKAEEQRQAN-------------NAKKNIRKKEKK------------SK-------------------------AKAAAAAAAEAAAS-------------------------------------------------------TTNGEANGVQESAATESK---------------AELEAAGDASNVKNEKEQTVDIATDTQELVGDGD---------AITAKSLVDISEVPPLIDANAN----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . * :: :: : * ::::.*:: :.***..:::::: : .: :*. : :: ::::*:* : .:::* *.**: :*** ** :::*:*:* : : :* :*** ::**::* *:* .: ::.:.* ** . * *:: *** : :**: **: *:*: :: :*: :* :***::.: :* :*:: *:: : * ::* :: ** :*: ::::**.:* ****:: ::* *::: :*: **:**:: *: ::*..* :::: *:: : :. * : :* :*:.* **** **. *: ::: .: : . : : : . .: : : . : . . .: * * . . :* .: :.: . : ::: . : . . : : . * ", "identical_positions": 90, "similar_positions": 179, "identity": "10.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3230", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63638-1", "uniprot_id": "SPEG_RAT", "id": "Q63638-1", "name": "Striated muscle-specific serine/threonine-protein kinase", "aln": "MQKARGTRGEDAGTRAPPSPGVPPKRAKVGAGRGVLVTGAGAGAPVFLRPLKNAAVCAGSDVRLRVVVSGTPEPSLSWFRDG----------QLLPTPVPEPSCLWLRNCGAQDAGVYSCSAQNERGKASCEAVLTVLEVRDSETAEDDISDVPGTQRLELRDDRAFSTPTGGSDTLVGTSLDTPPTSVTGTSEEQVSWWGSGQTVLEQEAGSGGGTRPLPGSPRQAQTTGAGPRHLGVEPLVRASRAN-------LVGASWGSEDSLSVASDLYGSAFSLYRGRALSIHVSIPPSGLRREEPDLQPQPASDALRPRPALPPPSKSALLPPPSPRVGKRALPGSSAQPPATPTSPHRCTQEPSLPEDITTTEEKRGKKPKSSGPSLAGTVESRPQTPLS--EASGR--------LSALG--RSPRLVRAGSRILDKLQFFEERRRSLERSDSPPAPLRPWVPLRKARSLEQPKSEGGAAWDTPGASQEELRSPRGSVAERR---RLFQQKAASLDERTRQRSATSDLELRFAQELGRIRRSTSREELVRSHESLRATLQRAPSPREPGEPPLFSRPSIPKTSRAVSPAATQPPPPSGAGKSGDETGRPRSRGPVGRTEPGEGPQQEIKRRDQFPLTRSRAIQECRSPVPPFTADPPESRTKAPSARKREPPAQAVRFLPWATPGVEDSVLPQTLEKNRAGPEAEKRLRRGPEEDGPWGAWDRRGTRSQGKGRRARPTSPELESSDDSYVS---------------AGEEPLEAPVFEIPLQNMVVAPGADVLLKCIITANPPPQVSWKKDGSVLHSEGRLLIRAEGERHTLLLREAQAADAGSYTATATNELGQASCASSLAVRPGASTSPFSSPITSDEEYLSPPEEFPEPGETWSRTPTMKPSPSQDRDSSDSSSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLA-PLQDVDVGAGEMALFECLVAGPADVEVDWLCRGRLLQPALLKCKMHFDG--RKCKLLLTSVHEDDSGVYTCKLSTVKDELTCSARLTVRPSL---------APLFTRLLEDVEVLEGRAARLDCKISGTPPPSVTWTHFGHPVNESEN----LRLRQDGGLHSLHIARVGSEDEGLYEVSATNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEH--GDLER------------------------------------------------------------LSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSD-DRRMTQYRDIHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPDGAPQVVAVTGRMVTLSWNPPRSLDMAIDPDSLTYTVQHQVLGSDQWTALVTGLREPEWAATGLKKGLHHIFRVLSSSGKSSSKPSAPSEPVQLLEHGPPLEEAPAVLDKQDIVYVVEGQPACVTVTFNHVEAQVVWRSCRGALLEPRTGVYELSQPDDDQYCLRICRVSRRDLGPLTCSARNRHGTKACSITLELAEAPRFESIMEDVEVGPGE-TARFAVVVEGKPLPDIMWYKDEVLLAES-NHVSFVYEENECSLVVLSAGSQDGGVYTCTARNLAGEVSCKAELSVHSAQTAMEVEGVGEDEE---------------HRGRRLSDYYDIHQEIGRGAFSYLRRVVERSSGLEFAAKFIP---------------SQAKPKASARREARLLARLQHDCVLYFHEAFERRRGLVIVTELCTEELLERMARKPTVCES----------------ETRTYMRQVLEGIGYLHQSHVLHLDVKPENLLVWDGAGGEEQVR-------ICDFGN----------AQELTPGEPQYCQFGTPEFVAPEIVNQ---SPVSGVTDIWP--------VGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTFLSLSREARG-------------FLIKVLVQDRLRP-----------------TAEETLEHPWFKTEAKGAEVSTDHLKLFLSRRRWQRSQISYKCHLVLRPIPELLRAPPERVWVAMPRR---QPPSGGLSSSSDSEEEELEELPSVPRPLQPEFSGSRVSLTDIPTEDEALG-----TPEAGAATPMDWQEQGRAPSKDQE------APSPEALP--SPGQESPDGPSPRRPELRRGSSAESALPRVGSRE----------PGRSLHKAASVELPQRRSPSPGATRLTRGGLGEGEYAQRLQALRQR------------------------------------------LLRGGPEDGKVSGLRGPLLESLGG--RARDPRMAR-------AASSEAAPHHQPPPE----SRGLQKSSSFS----------QGEAEPRGRHRRAGAPLEIPVARLGARRLQESPSLSALSETQPPSPALPSAPKPSITKSPE--------PSAATSRDSPQPPAPQPVPEKIPEPKPEPVRAAKPAQPPLALQMPAQSLTPYAQIMQSLQLSSPTLSPQ----VPPSEPKPHAAVFARVASPPPGASEKRVPSARIPPVLAEKVRVPTVPPRPGSSLSGSIENLES--------------------------------------EAVFEAKFKRSRESPLSRG----LRLLSRSRSEERGPFRGAED-DGIYR-------PSPAGTPLELVRR--PERSRSVQD-----------LRVAGEP---GLVRRLSLSLS----------QKLRRTPPGQRHPAWESR------------------------SGDGESSEGGSSARGSPVLAVRRRLSSTLERLSSRLQ-----------------------------------------------------RSGSSEDSGGASGRSTPLFGR---LRRATSEGESLR----------RLGVPHNQLASQTGATTPSAESLGSEASGTSG-SSAPGESRSR---HRWGLSRLRKDKGLSQPNLSASVQEDLGHQYVPSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPTPRISWMKDKQSLRSEPSVVIVSCKDGRQLLSIPRASKRHAGLYECSATNVLGSITSSCTVAVARTPG---------KLAPPEVPQTYCDTALVLWKPGDSRAPCTYTLERRVDGESVWHPVSSGIPDCY---------------------------------------------------------------------------------------------------------------YNVTQLPVGVTVRFRVACSNRAGQ------------------------------------------------------------------------------------------------------------------------------GPFSNPSEKVFIRGTQDSPAQSAAAPRDAPVTSG-------------------------------PTRAPPPDSPTSLVPTPPLAPQVSQASTLSPSTSSMSANQALSSLKAVGPPPATPPRKHRGLLATQQAEPSP-------------------------------------PSILVTPSEHKSFVPDTGTLTPTSSPQGVKPAPSSSS--------------------------------------------LYMVTSFVSAPPDPQPPAPE---------PPPEPTKVTVRSLSPAKEVVSSP-----------------------------------------------------------------------------------------TPESTTLRQGPPQKPYTFLEEKARGRFGVVRSCRENATGRTFVAKIVPYAAEGKRRVLQEYEVLRTLHHERLMSLHEAYITP--RYLVLIAESCGNRELLCGLSDRFRYSEDDVATYVVQLLQGLDYLHGRHVLHLDIKPDNLLLAADN--ALKIVDFGSAQPYNPQALKPLGHRTGTLEFMAPEMVRGDPIGSATDIWGAGVLTYIMLSGYSPFYEPDPQETEARIVGGRFDAFQLYPNTSQSATLFLRKVLSVHPWSRPSLQDCLAHPWLQDAYLMKLRRQTLTFTTNRLKEFLGEQRRRRAEAATRHKVLLRSYPGSP------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62407-1", "uniprot_id": "SPEG_MOUSE", "id": "Q62407-1", "name": "Striated muscle-specific serine/threonine-protein kinase", "aln": "MQKARGTRGEDAGTRAPPSPGVPPKRAKVGAGRGVLVTGDGAGAPVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLSWFRDG----------QLLPPPAPEPSCLWLRSCGAQDAGVYSCSAQNERGQASCEAVLTVLEVRDSETAEDDISDVPGTQRLELRDDRAFSTPTGGSDTLVGTSLDTPPTSVTGTSEEQVSWWGSGQTVLEQEAGSGGGTRPLPGSPRQAQTTGAGPRHLGVEPLVRASRAN-------LVGASWGSEDSLSVASDLYGSAFSLYRGRALSIHVSIPPSGLHREEPDLQPQPASDALRPRPALPPPSKSALLPPPSPRVGKRALPGPSTQPPATPTSPHRRAQEPSLPEDITTTEEKRGKKPKSSGPSLAGTVESRPQTPLS--EASGR--------LSALG--RSPRLVRAGSRILDKLQFFEERRRSLERSDSPPAPLRPWVPLRKARSLEQPKSEGGAAWGTPEASQEELRSPRGSVAERR---RLFQQKAASLDERTRQRSATSDLELRFAQELGRIRRSTSREELVRSHESLRATLQRAPSPREPGEPPLFSRPSTPKTSRAVSPAATQPPPPSGAGKSGDEPGRPRSRGPVGRTEPGEGPQQEIKRRDQFPLTRSRAIQECRSPVPPYTADPPESRTKAPSGRKREPPAQAVRFLPWATPGVEDSVLPQTLEKNRAGPEAEKRLRRGPEEDGPWGPWDRRGTRSQGKGRRARPTSPELESSDDSYVS---------------AGEEPLEAPVFEIPLQNMVVAPGADVLLKCIITANPPPQVSWKKDGSMLHSEGRLLIRAEGERHTLLLREAQAADAGSYTATATNELGQATCASSLAVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGETWPRTPTMKLSPSQDHDSSDSSSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLA-PLQDVDVGAGEMALFECLVAGPADVEVDWLCRGRLLQPALLKCKMHFDG--RKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSL---------APLFTRLLEDVEVLEGRAARLDCKISGTPPPSVTWTHFGHPVNEGDN----LRLRQDGGLHSLHIARVGSEDEGLYEVSATNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEH--GDLER------------------------------------------------------------LSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSD-DRRMTQYRDIHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPDGAPEVVAVTGRMVTLSWNPPRSLDMAIDPDSLTYTVQHQVLGSDQWTALVTGLREPAWAATGLKKGIQHIFRVLSSSGKSSSKPSAPSEPVQLLEHGPPLEEAPAVLDKQDIVYVVEGQPACVTVTFNHVEAQVVWRSCRGALLEARTGVYELSQPDDDQYCLRICRVSRRDLGPLTCSARNRHGTKACSVTLELAEAPRFESIMEDVEVGPGE-TARFAVVVEGKPLPDIMWYKDEVLLAES-NHVSFVYEENECSLVLLSAGSQDGGVYTCTARNLAGEVSCKAELSVLSAQTAMEVEGVGEDEE---------------HRGRRLSDYYDIHQEIGRGAFSYLRRVVERSSGLEFAAKFIP---------------SQAKPKASARREARLLARLQHGCVLYFHEAFERRRGLVIVTELCTEELLERMARKPTVCES----------------ETRTYMRQVLEGICYLHQSHVLHLDVKPENLLVWDGAGGEEQVR-------ICDFGN----------AQELTPGEPQYCQYGTPEFVAPEIVNQ---SPVSGVTDIWP--------VGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTFLSLSREARG-------------FLIKVLVQDRLRP-----------------TAEETLEHPWFKTEAKGAEVSTDHLKLFLSRRRWQRSQISYKCHLVLRPIPELLRAPPERVWVAMPRR---QPPSGGLSSSSDSEEEELEELPSVPRPLQPEFSGSRVSLTDIPTEDEALG-----TPEAGAATPMDWQEQERTPSKDQE------APSPEALP--SPGQESPDGPSPRRPELRRGSSAESALPRVGSRE----------PGRSLHKAASVELPQRRSPSPGATRLTRGGLGEGEYAQRLQALRQR------------------------------------------LLRGGPEDGKVSGLRGPLLESLGG--RARDPRMAR-------AASSEAAPHHQPPPE----SRGLQKSSSFS----------QGEAEPRGRHRRAGAPLEIPVARLGARRLQESPSLSALSETQPPSPARPSVPKLSITKSPE--------PSAVTSRDSPQPPEPQPVPEKVPEPKPEPVRAAKPAQPPLALQMPTQPLTPYAQIMQSLQLSSPTLSPQD-PAVPPSEPKPHAAVFARVASPPPGVSEKRVPSARTPPVLAEKARVPTVPPRPGSSLSGSIENLES--------------------------------------EAVFEAKFKRSRESPLSRG----LRLLSRSRSEERGPFRGAED-DGIYR-------PSPAGTPLELVRR--PERSRSVQD-----------LRVAGEP---GLVRRLSLSLS----------QKLRRTPPGQRHPAWESR------------------------SGDGESSEGGSSARASPVLAVRRRLSSTLERLSSRLQ-----------------------------------------------------RSGSSEDSGGASGRSTPLFGR---LRRATSEGESLR----------RLGVPHNQLGSQTGATTPSAESLGSEASGTSG-SSAPGESRSR---HRWGLSRLRKDKGLSQPNLSSSVQEDLGHQYVPSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPRISWMKDKQSLRSEPSVVIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARIPG---------KLAPPEVPQTYHDTALVVWKPGDGRAPCTYTLERRVDGESVWHPVSSGIPDCY---------------------------------------------------------------------------------------------------------------YNVTQLPVGVTVRFRVACSNRAGQ------------------------------------------------------------------------------------------------------------------------------GPFSNPSEKVFIRGTPDSPAQPAAAPRDAPVTSG-------------------------------PTRAPPPDSPTSLAPTPALAPPASQASTLSPSTSSMSANQALSSLKAVGPPPATPPRKHRGLLATQQAEPSP-------------------------------------PSIVVTPSEPRSFVPDTGTLTPTSSPQGVKPAPSSTS--------------------------------------------LYMVTSFVSAPPAPQAPAPE---------PPPEPTKVTVRSLSPAKEVVSSP-----------------------------------------------------------------------------------------TPESTTLRQGPPQKPYTFLEEKARGRFGVVRSCRENATGRTFVAKIVPYAAEGKRRVLQEYEVLRTLHHERLMSLHEAYITP--RYLVLIAESCGNRELLCGLSDRFRYSEDDVATYVVQLLQGLDYLHGHHVLHLDIKPDNLLLAADN--ALKIVDFGSAQPYNPQALKPLGHRTGTLEFMAPEMVKGDPIGSATDIWGAGVLTYIMLSGYSPFYEPDPQETEARIVGGRFDAFQLYPNTSQSATLFLRKVLSVHPWSRPSLQDCLAHPWLQDAYLMKLRRQTLTFTTNRLKEFLGEQRRRRAEAATRHKVLLRSYPGSP------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15772-5", "uniprot_id": "SPEG_HUMAN", "id": "Q15772-5", "name": "Striated muscle preferentially expressed protein kinase", "aln": "MQKARGTRGEDAGTRAPPSPGVPPKRAKVGAGGGAPVA--VAGAPVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDG----------QLLPAPAPEPSCLWLRRCGAQDAGVYSCMAQNERGRASCEAVLTVLEVGDSETAEDDISDVQGTQRLELRDDGAFSTPTGGSDTLVGTSLDTPPTSVTGTSEEQVSWWGSGQTVLEQEAGSGGGTRRLPGSPRQAQATGAGPRHLGVEPLVRASRAN-------LVGASWGSEDSLSVASDLYGSAFSLYRGRALSIHVSVPQSGLRREEPDLQPQLASEAPR-RPAQPPPSKSALLPPPSPRVGKRSPPGPPAQPAATPTSPHRRTQEPVLPEDTTT-EEKRGKKSKSSGPSLAGTAESRPQTPLS--EASGR--------LSALG--RSPRLVRAGSRILDKLQFFEERRRSLERSDSPPAPLRPWVPLRKARSLEQPKSERGAPWGTPGASQEELRAP-GSVAERR---RLFQQKAASLDERTRQRSPASDLELRFAQELGRIRRSTSREELVRSHESLRATLQRAPSPREPGEPPLFSRPSTPKTSRAVSPAAAQPPSPSSAEKPGDEPGRPRSRGPAGRTEPGEGPQQEVRRRDQFPLTRSRAIQECRSPVPPPAADPPEARTKAPPGRKREPPAQAVRFLPWATPGLEGAAVPQTLEKNRAGPEAEKRLRRGPEEDGPWGPWDRRGARSQGKGRRARPTSPELESSDDSYVS---------------AGEEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLA-PLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDG--RKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSL---------APLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESEN----LRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEQ--GELER------------------------------------------------------------LSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSD-DRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPDGAPQVVAVTGRMVTLTWNPPRSLDMAIDPDSLTYTVQHQVLGSDQWTALVTGLREPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQLLEHGPTLEEAPAMLDKPDIVYVVEGQPASVTVTFNHVEAQVVWRSCRGALLEARAGVYELSQPDDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEAPRFESIMEDVEVGAGE-TARFAVVVEGKPLPDIMWYKDEVLLTES-SHVSFVYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVEGVGEDED---------------HRGRRLSDFYDIHQEIGRGAFSYLRRIVERSSGLEFAAKFIP---------------SQAKPKASARREARLLARLQHDCVLYFHEAFERRRGLVIVTELCTEELLERIARKPTVCES----------------EIRAYMRQVLEGIHYLHQSHVLHLDVKPENLLVWDGAAGEQQVR-------ICDFGN----------AQELTPGEPQYCQYGTPEFVAPEIVNQ---SPVSGVTDIWP--------VGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTFLSLSREARG-------------FLIKVLVQDRLRP-----------------TAEETLEHPWFKTQAKGAEVSTDHLKLFLSRRRWQRSQISYKCHLVLRPIPELLRAPPERVWVTMPRR---PPPSGGLSSSSDSEEEELEELPSVPRPLQPEFSGSRVSLTDIPTEDEALG-----TPETGAATPMDWQEQGRAPSQDQE------APSPEALP--SPGQEPAAGASPRRGELRRGSSAESALPRAGPRE----------LGRGLHKAASVELPQRRSPSPGATRLARGGLGEGEYAQRLQALRQR------------------------------------------LLRGGPEDGKVSGLRGPLLESLGG--RARDPRMAR-------AASSEAAPHHQPPLE----NRGLQKSSSFS----------QGEAEPRGRHRRAGAPLEIPVARLGARRLQESPSLSALSEAQPSSPARPSAPKPSTPKSAE--------PSATTPSDAPQPPAPQPAQDKAPEPRPEPVRASKPAPPPQALQTLALPLTPYAQIIQSLQLSGHAQGPSQGPAAPPSEPKPHAAVFARVASPPPGAPEKRVPSAGGPPVLAEKARVPTVPPRPGSSLSSSIENLES--------------------------------------EAVFEAKFKRSRESPLSLG----LRLLSRSRSEERGPFRGAEEEDGIYR-------PSPAGTPLELVRR--PERSRSVQD-----------LRAVGEP---GLVRRLSLSLS----------QRLRRTPPAQRHPAWEAR------------------------GGDGESSEGGSSARGSPVLAMRRRLSFTLERLSSRLQ-----------------------------------------------------RSGSSEDSGGASGRSTPLFGR---LRRATSEGESLR----------RLGLPHNQLAAQAGATTPSAESLGSEASATSG-SSAPGESRSR---LRWGFSRPRKDKGLSPPNLSASVQEELGHQYVRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPG---------KLAPPEVPQTYQDTALVLWKPGDSRAPCTYTLERRVDGESVWHPVSSGIPDCY---------------------------------------------------------------------------------------------------------------YNVTHLPVGVTVRFRVACANRAGQ------------------------------------------------------------------------------------------------------------------------------GPFSNSSEKVFVRGTQDSSAVPSAAHQEAPVTSR-------------------------------PARARPPDSPTSLAPPLAPAAPTPPSVTVSPSSPPTPPSQALSSLKAVGPPPQTPPRRHRGLQAARPAEPTL-------------------------------------PSTHVTPSEPKPFVLDTGTPIPASTPQGVKPVSSSTP--------------------------------------------VYVVTSFVSAPPAPEPPAPE---------PPPEPTKVTVQSLSPAKEVVSSPGSSPRSS---------------------------------------------------------------------------------PRPEGTTLRQGPPQKPYTFLEEKARGRFGVVRACRENATGRTFVAKIVPYAAEGKRRVLQEYEVLRTLHHERIMSLHEAYITP--RYLVLIAESCGNRELLCGLSDRFRYSEDDVATYMVQLLQGLDYLHGHHVLHLDIKPDNLLLAPDN--ALKIVDFGSAQPYNPQALRPLGHRTGTLEFMAPEMVKGEPIGSATDIWGAGVLTYIMLSGRSPFYEPDPQETEARIVGGRFDAFQLYPNTSQSATLFLRKVLSVHPWSRPSLQDCLAHPWLQDAYLMKLRRQTLTFTTNRLKEFLGEQRRRRAEAATRHKVLLRSYPGGP------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q696W0-1", "uniprot_id": "SPEG_DANRE", "id": "Q696W0-1", "name": "Striated muscle preferentially expressed protein kinase", "aln": "MRKVTEE-----------------KRHSSSMNSSTVETSFIAAPPVFLRKLKWAAVAAGCDVRLRVCVGGNPRPTLHWYHND----------DPLVIDHEDYDGLWIRDCQQADGGLYTCVAVNHLGEARTSAVLAVLDLEEDSNSTEDESAEP---HVSMEMKEQFMPPQG-------EAINSQPTG----------------------------------------------------------------------------------------------RGRAMLSHIPSDGLVVEREMRALGSR----------------APGLQEPLSPGRGQLDFKTSEATPFVQTQPPHK-AQASITKSDVDATIDSTATKIKGTKTAMNGAEVSIKSSKITGSHQSGG--------LQDPSSIQTPKVSQASSKILDRVRAFEEQS---HNSNMPKVSSRLSWGFNRTSSCNSEDETCKAGKFQANTKS--------DVALKR---SFFKQKASSLEEQS--TYVQKNFQSKLSEELHRIKKLVGKSNIKKAFSMEQLTQTDKQS------------------------SVSTESVPTQVIQKSEETG-------------------------------------------------------------------------------------KHFTNLKAVPDAKERWTTLPKEQSSR--------------------LPKINLADKTKQP---------------ENE--------------------------------TPPEMNENQEN---------------------------------NSKPTQLLDGQVLNEKVSFIPGQCSPMLPRTNVSRKWPKSPAQPMVKDG--------LVQAPQKPPRLLESISTPPTPFKMTIPTIVVEN--------------KPVDEELDQKEGQIMRQNRDALDDFHTSVEKSIAEAPMSELPRKDALGTAGSELLQCIIKENTVARAPAESLLIITRPMQDVKVKAGETALLECFIAGSQAVDVDWLANGKLIQPALFDCKMQFDG--HRCRLLFKSAHENDSGCYTCKLSTAKEELICTANLLVIPSK---------EPLFTRKLEVLEAIEGRSAQFDCKVSGCPPPEVTWTHCEKPLVESDN----IHILNVNGHHSLLITHVNKESEGLYTAIAQNVHGKAASSAELYVQEPRPAISTHMSRLEKMPSIPEEPEVPEGEVER------------------------------------------------------------RTMPDFIKPLSDLEVIEGKEAVLKCRVTGLPYPKITWYHNGKKIESTN-DRKMTQYRDVHSLVIQSVCHDHSGVYKCVISNKVGKAACYAHLYVAVSLPEPPDGPPVIESVTGRMILLSWKKPKNLDPSIDPASLMYVVQQQVLGSTQWTTIASSLTDTSYTVTSLSKGVCYSFRVLSTTGKTLSKPSQPTDLVQLVDRGEYFRKAPVIIDKPDIVYAVENQPVTITITINHVQATCTWK-RRGVVLVNKLGALEMTTPDDDQHALHIAKVKSTDVGQLIFMANNQYGSDLGTLQLVIAVPPIFETIMEDLDVCVGE-TCHFAVVVDGKPDPDILWYKDGVLLAES-SHLTFVYDDRECSLVVLNAQPEDVGVYTCTAKNLAGSVSCKAELTVHTAQNVEEEEEQMEDEATI------------LRRMRMLTDYYDIHKEIGRGAFSYVKRVKHKND-QSFAAKFIS---------------VRAKKKTCALRELALLAELDHKSIVRFHDAFEKRRVVIILTELCHEELLERITKRTTILES----------------EVQSIIRQLLEGIEYLHQNDIIHLDLKPENILMAD--QKTDQIR-------ICDFGN----------ALKVKPNEELYCKYGIPEFIAPEIVNQ---SPISKSTDIWP--------VGVITYLCLTGVSPFAGENDRDTLLNIRNYNVAFEESMFKDLCREAKG-------------FIIKVLVSNKLRP-----------------DATECLLHPWFKSLTKGKSINTTLHKQVLARRKWQCSLIRYGSKMVMRSISELLDDSSSHVSLAVPRN---LKDGSPPPSSSSDSDEDIDELPFIPMPHTMMFSGSRMSLTEIHEVDDKVIRGSNESYKKNLNQLDDIPESQIIAGQKNEDYLKNPKRTDNCLQRGSSVEVDQVASKTRRGLMRRGSSADSALLLQITPEDNEIKDTTEDSQKHMKKAVSMELPHR-SSSPKTAKLSKE-----DYALKLDLMRQR------------------------------------------LLKGGTVNKNMSGLRGPLLETLGVDDERRTSSLDRNFRNARLNASGDSGTFNNDSSEETYQKPAFRKRSSLR----------DENSESISLHRRSGAPLEIPSSSTGDHNVLKIKSTILDENKANLPPLFPRDISSKPPTPVL--------ENKQVSKEEANSDVLIMNSSRSAFNLEDTEIKVEEMKEQDSVPENMNKSTEFPLDILPHDISSNYCSKLQANGKKASFLTPLPTPVLKISQP------NIQPTAGRPGVFASAFSAHQP------NLRSDIKNIDS--------------------------------------EEIFEARFKK-RESSLAHG----LKRLTRTKSEESSPVPQRKSDEVVYR-------PGPVGSPLEFGSTGLKEKSKSVQD-----------LREVDKEVGLGLIGRFSMRARKLQPIDKKEKKEISDSVTNKRQLTWATRRSKSLDKKE------------NFETNKENLEKDTKKIAESPVLAVRRKFESNVSGIFDRVHSRSKDRKDKETKPHIDAEAPNVEKQDMKKINDSPVLALRKKFETKVSGISYRKQSQSEGEGTKFEGQKTPLFSR---HHRSQSDGLIHK----------KMDIPENQLPLQT-TTISSKETLNSSSSAHSIESSQTPETEIRSRWDRWGLSRGKRDRTPSNSRAPATPKE-----------DFPPVFHIALKDHVLLEGNPVTLSCLPAGSPEPKILWLKDKKPLKLCDGMNLEACPDGRQLLMIMNISKKDAGIYECVATNNLASVTTSCILTLACIPN---------CPGTPEIRQIYNNTVLVQWKPSDTKVPCTYTIEKKFDGDDKWLTEATGVTDCF---------------------------------------------------------------------------------------------------------------FNSSELPSGSTIRFRVACVNKAGQ------------------------------------------------------------------------------------------------------------------------------SPYSNESDGVSIDTKVTPQHQPAKMKTHSPASFP-------------------------------AMTAAVATSAFSLSLPSVFSQSISPTPAQSADVSNTFLEVQSSPKMSTPLDLPKPASSVNTMPPITQTQTVS-------------------------------------PRSYTAPPSIGRSISPVPTYVPATCS--LAPTPVSPS--------------------------------------------VIVVSSISPIGEGASSPTPE---------TPTG-------------QAVSST------------------------------------------------------------------------------------------KSETTLRQGVPQKPYSFLDEKARGRFGVIRDCRENATGKMFIAKIIPYDQQTKQTIIKEYEILKSLRCERIMALHEAYITP--RYLVLITEYCSGKEILQNLIDRFCYSEDDVVGFIVQILQGLEYLHNCKILHLDIKPDNIMVTNLN--VIKIIDFGSAQRFNPLSLQQCSRYLGTLEYMAPEMLKGDLVGPPADIWSLGVLSYIMLSGRHPFEDKDPQLTEAKIHEAKFDSTKLYPKVSQSASTFLKKILNSYPWCRPTIKDCLNHSWLHDSYLKKLRRQTLTFTTTRLKEFMGEHQRRCAESATKHKVILRVYQGGPSSPASPTKYTTQ------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8DYP0-1", "uniprot_id": "OBSCN_DROME", "id": "A8DYP0-1", "name": "Protein Obscurin", "aln": "-MDAVADIVFVSRDYQAQSLATDEISVSRGDLVELISSKASEKSRCFVRMFDSGDSPKEGWVPIDILEFNPTMSSSNGKESGDAEFRKLTILRELVETEEEFSRDLLHVVEKYIKGIDKPVVPRSVRDNKDIIFCNFLQIAEFHNNVLKEGLKCYSNQPNMVAKTFLRLERDFDKHVVYCQNEPLAQDYLGSSPDAKKYFQELSKQLGDDKSLAEHLKLPIQRINDYQLLFKDFIKYSLSLKENVKDLERALELMLSVPSRAYDNRFLSSIEGCRGNIYKLGRLLLHAWCNVVDKEGKAHDRYCFLFKSRILVTKVRKISENRSVFILQNIVKLPLCNIELKADEKQIHLSLKAPEANSFLPIDIKPHGPEAHLTWFNEISSHINQDVTLQEHNADDLKVDASQIASESELILHLPQRAEAHDPNLSVRPSDVAENYFLSKETKERLQHEQQELLKLEQEAIELYKKQQSSKSVSSKTESVEITSSQVKSSSEVRKVVSPPPPPQAQVKEVTPVKVVSSPPPPKEITPAKVATPPPQPQVVTSPVKEVAPPPQPRAVASPAKEVTPSQSEPVKAPSPIKEVRKEVPPSASHSKEVEALVATEIRESLTETRSTVVESGQSSEIREEIVVTEESSLEGKQVVALEREPSP---CSIPKIQVYRPVECENPVVTKHKPIELKDIVGYSESLRDGDTAPAGGSPGRQQGYSANITDHASLTIWNNRLANIAGDRSGANQHLQQSGPPPPPIPPNFTRMPGFFQPLPLIAYETTIEILIVKARPPSPPPPPPPTIKRVLVHTESLEQKTQNFFEGIYDAASSDTSLRNAKQKIRSIKSTVLKSKDSTNYAQDTVQKAKARDFLHIFTPPVKKRPIYEIVEEPVNIFELEGDYTESIADDFREPSADFEARGQSVGGMDDYYSGYSRASTRRYETKTRDYDRGTSYDSTVERSQYGISSRRDRSSVDKVEARSSLLATGRTESRAASRAESRAESRASYSVAESRAGIRSSSRLQEDRPLRSVDKPVVVKMLKSVQVEPGETAHFEIQFK-DQPGLVTWLKDNKPLEDRLADRITQTAAPMNSYRLDIKNCSETDAGTYTIRAQSASETTTVSAQLAVGQAPGHDETKTNTEPAFLVSLKDAEMIENTLFRFMVKIIGDPKPRVKFYKDEKEILETNDRIQIIRDKDYLGFYELVIADVQKTDAGTYSCKATNKHGEANCEAIATTVEDKNPFGALSGQILPAGEKPVFQWKRNGEEFDPEERFKVLFGEDEDSLALVFQHVKPEDAGIYTCVAQTSTGNISCSAELSVQGAIQTLNREPEKPTLVIEHREANASIGGSAILELQCKGFPKPAVQWKHDGEVIQVDDRHKFMYEDEESMSLVIKNVDTVDAGVYTIEAINELGQDESSINLVVKAPP------------KIKKITDITCSAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESNVKISSSSIGKSLEKVVVEVKEIKLSQAGNYSIKATNDLSQTSEYWSCTVKSKPVIVKNFESEYIHGEKENVQMTVRIDAYPEAKLTWYHDETEIKITDSKYTVSSDGNAYTLKITGATRVDAGKYTVKATNEHGSATSSTQLLIKCAPEFTHKLKNITVAEGDSNVELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDFKLIMNQVATNMQGNYTCKIMNDYGKLEDNCVVTVNCKPKVKRGLKNVEVQEGKSFTLEVEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQRIENYYLTLNLARTEDAGTYEMKATNFIGETTSTCKVAVLTSEALSLEQTVTKTLIATTEEPEEGAVPEIVHVDVFQQHSYESVPLKYEVIATGIPKPEAIWYHDGKPITPDKHTAITVDGDHYKLEVQSLDLVDAGEYKVVVQNKVGEKSHQGELSLSGIAEYRKPILTQGPGLKDIKVNKGDKVCEPVVFTADPAPEIVLLKDGQPVVETNNVKLKVDKKDAENGLVQYTCTLNILEAEIKDSGRYELKVKNKYGELVTSGWIDVLAKPEISGLNDTKCLPGDTICFEALVQANPKPKVSWTRGNENLCNHENCEVIADVDADKYRLVFQSVSPCEDGKYTITATNSEGRAAVDFNLAVLVEKPTFIVQPESQSIHDYRPVSTKVLVHGVPLPTIEWFKDDKPINYEAINKPGKDKLYAKEDTKKGTDQIESVLDIKSFRENDVGAYTCVATNEIGVTKAPFKLAMLS---LAPSFVKKLDNALDVLQGEPLVLECCVDGSPLPTVQWLKDGDEVKP--SESIKISTNPDGLVKLEINSCQPNDSGAYKLIISNPHGEKVALCAVAVKPEEMQPKFLKPITSQTVVVGEPLKLEAQVTGFPAPEVKWYKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLDAGVYKCLIANKGGEIEGVSKVEIVPKESKPVFVAELQDASSIEGFPVKMDIKVVGNPKPKLQWFHNGHEIKPDASHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAPKADETATEEAPQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSKDGVTLTPNERLLMTCDGKHIGLTIKPAEAADSGNYTCLLANPLGEDSSACNANVRKVYKPPVFTQKISDQQQVFGNNAKIPVTVSGVPYPDLEWYFQDKPIPKSEKYSIKNDGDHHMLIVNNCEKGDQGVYKCIASNREGKDITQGRLDIVNEIKKHSRSEPPVFLKKIGDCDIYEGMVAKFTACATGYPEPEVEWFKNDQKLFPSDRFLIDIEPNGLLRLTIKNVTEYDVGRYSCRIFNPYGDDICHAELFYDSLDSQQKPLEDQYTDFKKYKKSGAPPPLSEGPIISRMTDRGLLLSWNPSVPLTPRYPITYQIEMMDLPEGDWRTLRTGVRSCACDIRNLEPFRDYRFRVRVENKFGVSDPSPYTQTYRQKLVPDPPKTYTYLPPGTDFRPETSPYFPKDFDIERPPHDGLAQAPQFLLREQDISYGVKDHNTELMWFVYGYPKPKMTYYFDDMLIESGGRFDQSYTRNGQATLFINKMLDRDVGWYEAVATNEHGEARQRVRLEIAEHPRFLKRPDETFIMARKNGRIEAKLVGIPLPEVHWFKDWKPIVDSSRIKISSYDPDIYVLSIHDSIIKDGGLYSISARNIAGSISTSVTVHIEENEDQYIYKTYGRHPYVRSKQLRYQDKYDIGDELGRGTQGITYHAVERSSGDNYAAKIMYGRPELRPFMLNELEMMNTFNHKNLIRPYDAYDTDRSVTLIMELAAGGELVRDNLLRRDYYTERDIAHYIRQTLWGLEHMHEMGVGHMGLTIKDLLISVVGGDIIKVSDFGLSRKINRHNLSTLDYGMPEFVSPEVVNKEGVNFSHDMWTVGLITYVLLGGHNPFLGIDDRETLTKIREGRWDFKDEIWTHISDDGRDFISRLLLYSPEERMDVKTALKHPWFFMLDRPVYDHDYQIGTDRLRNYYDHFRDWYANASCKNYFRRRRLSGCFQHPSKMVYPPGHVYTPENTPEPLPEPRIRAKREEVVSKYLHPDYELGLIQSESHYQYGPDTYLLQLRDVNFPVRLREYMKVAHRRSPSFALNDSVDWSLPVIRERRRFTDIMDEEIDDERTRSRISMYAANESYSIRRLRTELGPRLDEYTEADAMIETQREGYPPFFREKPQTIAITENQPSHIHCFAVGDPKPCVQWFKNDMVLTESKRIKISVDEDGRSILRFEPALHFDVGVYKVVARNKVGQTVARCRIVVATLPDAPDSPEISANSGTEILLRWKQPRDDGHSTVLCYSLQYKLSNCDAWTTVADNIDHEFYLLHDLQPNTNYQFRLASKNRIGWSEMGIPVSASTVGGDAPKIHITKAMKHLQQLTENGHQVVPEEERVHTDYHCEREPPNWVTDSSVSDKYSFISEIARGEFSTIVKGIQKSTDTVVVAKILEVTDENEDNVVAEFDNFKTLRHERIPALFSAYKPLNVPIAIFVMEKLQGADVLTYFSSRHEYSEQMVATVVTQLLDALQYLHWRGYCHLNIQPDNVVMASVRSIQVKLVDFGSAKKVNKLGMKVT--PCGSLDFQPPEMINDEPIFPQSDIWSLGALTYLLLSGCSPFRGADEYETKQNISFVRYRFENLFKEVTPEATRFIMLLFKRHPTKRPYTEDCLEHRWLMSSDYMVRKRERAIFLGSRLKTFCDEYHDLKNASATSSKVLNTVAGGPTPTQLLRSNSIQEELLTTF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . . : . *:* :. . * : : . . .: ... * : . :: *: . . . . .*:: : . . . : .: . : . :. . . * :: : : * . : .*. : . . . . : .: : . :. . * . : *.: * : :. :* ...: . . .. . : :.. .*. ::.:.:. : . :.: : : .. : . : . . :.: . . . * :: :... : . . . * : . :. : * : * . . : : . . : : : . . . ..: : . ::. : * : * . :. : : : . ::. ::.*.* .** * :* . * ** .: :: * . : . . :* :.. * *:* ** : .:..: :*.* * : * * *: * :*. :: *: * * * *.: : : * :: :: : * :.* *: * . . * * * * **:* ..* . * : . . .:: . * *: * :: : :. . .*:*: : .*:* * : * *:*. *: : .: * : .: **: * .:***. *::*: . :* * :: :: . ..:. *: .: . : . .. : *: . .. ..* * : .: : . * : . ... *.::.: : * : . .. . :. . .*.: : *:* .. * * * *.:*: : * : .* * :::: * *: . .:.* *:. * *. ** * : : *. ... .* : .: .*:: .. .: * ***. * *.:. :. ::* .. . * : : : :.* ::*::: :*: . .:* . . .* . : . * : : : .:. * :: .:: :. * :. : : : ::* * : . :.* * :: : .. : *.:: : ::. .: . ***** .*: .:: *:: : * .: ::. ::::* : : : .: :.. : ::.**. . :* . : :: :. . . : . : : : :::. . :: .. : * . .: . .::. : : * : ... : . :. : . . * . : : . : . . **. :. * . ..:*: . .. : :* . * :: . **: .. :.. .* : :. .. : . ::. **: :.:. : * :: : . . . * .: . . . . . . . . : . . . .. .: . . . .. * *::. .: :..: : :::. .. . . :: * :. :.: .* . :*. . ..* * ::. .* ** . : : * * : : : ::: . . . :* .: ::. . . ..:* * : .*. :* .: .:: . . .: . *. : : . *: . . :: :. * * .: .:: : : . .. * *.: *:** :.: : : : . :* * :..*:*. * * .*:::* : : . . * :. : : . ** .: .*:. * .: .* : * * . . *: * . :.: *. * . .. .. . * : . : : . . : . . :: * . . . : . * . . . :*::: .. .: . * : .. . : :. .. *:*:.* ***.*..: :::*. .:***: : : :: *:: :::*: **: :*..** . ::: * . ::* : .*. ***: *. :.*:*:.*:*** **:*:***:::: . :*::*****: * .:: *:*:: .***:..: : . :***. *.*:*::*** ** * *: .* :: :*: :.: .*: *: ::. :* ** :*** * ** .: :*: * .*** * .* : :** **: * . ", "identical_positions": 303, "similar_positions": 856, "identity": "7.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3231", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ARU0-1", "uniprot_id": "A0A8I6ARU0_RAT", "id": "A0A8I6ARU0-1", "name": "", "aln": "MKILRCCFKYTLQQKVFILFLTLWLFSLLKLLNVGRLLFPQRDIYLVEYSLSTSPFVRNRFPDTGDAARDAVNCSGVYEHEPLEIGKSLEIRRRNIIDLEDGDVAVMTSDCDIYQTLRQYHEKPVSRVEEDFPIAYSLVVHKDAIMVERLIRAIYNQHNLYCIHYDLKSPDAFKAAMNNLAKCFSNIFIASKLEAVEYAHISRLQADWNCLSDLLKSSVQWKYVINLCGQDFPLKSNFELVTELKKLRGRNMLETVRPPTGKMERFTYHHELRQVPYEYMKLPVKTNVSKGAPPHDIEVFVGSAYFVLSQAFVKYIFNSSLVKDFFAWSKDTYSPDEHFWATLIRIPGIPGGISRSSQDVSDLQSKTRLVKWNYYEGFFYPNCTGSHLRSVCIYGAAELRWLIKEGHWFANKFDSKVDPVLIKCLAEKLEEQQRKLIALSSEKSITEGNPKATHKITTGLRASDTES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q649-1", "uniprot_id": "GCNT4_MOUSE", "id": "E9Q649-1", "name": "Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4", "aln": "MKIFRCCFKYTLQQKLFILLLTLWLFSLLKLLNVGRLLFPQRDIYLVEYSLSTSPFVRNRFPESGDAARDNVNCSGVYEHEPLEIGKSLEIRRRSIIDLEDGDVVAMTSDCDVYQTLRQYHEKLVSREEEDFPIAYSLVVHKDAIMVERLIRAIYNQHNLYCIHYDLKSPDTFKAAMNNLAKCFPNIFIASKLETVEYAHISRLQADWNCLSDLLKSSVQWKYVINLCGQDFPLKSNFELVTELKSLQGRNMLETVRPPSAKTERFTYHHELRQVPYDYMKLPVKTNVSKGAPPHNIQVFVGSAYFVLSRAFVKYIFNSSLVEDFFAWSKDTYSPDEHFWATLIRIPGIPGGISSSSQDVSDLQSKTRLVKWFYYEGFLYPNCTGSHLRSVCIYGAAELRWLLNEGHWFANKFDSKVDPILMKCLAEKLEEQQRKLIALSSEKFMTEG-TRQSHTL-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P109-1", "uniprot_id": "GCNT4_HUMAN", "id": "Q9P109-1", "name": "Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4", "aln": "MKIFKCYFKHTLQQKVFILFLTLWLLSLLKLLNVRR-LFPQKDIYLVEYSLSTSPFVRNRYTHVKDEVRYEVNCSGIYEQEPLEIGKSLEIRRRDIIDLEDDDVVAMTSDCDIYQTLRGYAQKLVSKEEKSFPIAYSLVVHKDAIMVERLIHAIYNQHNIYCIHYDRKAPDTFKVAMNNLAKCFSNIFIASKLEAVEYAHISRLQADLNCLSDLLKSSIQWKYVINLCGQDFPLKSNFELVSELKKLNGANMLETVKPPNSKLERFTYHHELRRVPYEYVKLPIRTNISKEAPPHNIQIFVGSAYFVLSQAFVKYIFNNSIVQDFFAWSKDTYSPDEHFWATLIRVPGIPGEISRSAQDVSDLQSKTRLVKWNYYEGFFYPSCTGSHLRSVCIYGAAELRWLIKDGHWFANKFDSKVDPILIKCLAEKLEEQQRDWITLPSEKLFMDRNLTTTS-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q71SG7-1", "uniprot_id": "GCNT4_DANRE", "id": "Q71SG7-1", "name": "Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4", "aln": "--MRRCAVLHRLRCKFYVFVVSLFVVVKLVYLKISM----DNSIYIEPYGVTRRSLKP--------QPLDGINCTAIYDLEPVEIGKSLEMRRKKIVEVDDGRIASFTADCKSYIEQRRYNEVLVTDEECNFPIAYSLVVHKNSAMVERILRAIYAPQNIYCIHYDQKSTKDFIAAMKNLESCFPNVFIASKIESVQYAHITRLKADLNCLSDLLSSEVKWKYVINLCGQDFPLKSNYELVTELRKLNGANMLETSRPSKVKKQRFQFRYQLKDVSYEYQKMPVKTSIAKDPPPHNIEMFVGSAYFVLSRDFVTYVMNNQLAKDFLQWSVDTYSPDEHFWASMARVPGVPGELARSEPDVSDLKSRTRLVKWNYLEERLYPKCTGTHRRSVCIYGAAELRWLLEDGHWFANKFDPKVDPVIIKCLEEKLEEKQ------------LQQCLRRVS-------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* . : *: *.:::.::*::. * *:: :..**: *.:: .: :**:.:*: **:*******:**:.*::::*. :. :*:**. * * * : *: * .***********:: ****:::*** :*:****** *:.. * .**:** .**.*:*****:*:*:****:**:** *******.*.::*****************:***:**:.*.* ***** :*.. * :** ::::*: *.*:* *:*::*.::* .***:*::**********: **.*::*..:.:**: ** ***********:: *:**:** :: * *****:*:****** * * :**.***:* **************:::*********.****:::*** *****:* : ", "identical_positions": 226, "similar_positions": 128, "identity": "48.39%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3235", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A779-1", "uniprot_id": "D4A779_RAT", "id": "D4A779-1", "name": "", "aln": "-MAEASHTLKQLELQNGSLEEEF--VVHSLENEPQNMMES---LSPRKYSSSLKFKANG--DYSGSYLTLSQPVS---TKRSPSPLGSSVRSS---PSLAKIQGG----------KQF-CDGIDKN------------------------------ISMKPPISFLSSTASLSGYPIGKADLDHYTGRDSERSFR-----------LSEKPPYSRYSSRNKSHDSVYFLGGAEGRKASGSLLTMWNGNS----------LSGTGSAPISR---SGAASMPSSPKQARKMNLQDNLPLQPRLSRHKEQASENVS---VRTRKYSGSSLSNMGAYSR--------------------SLPRLYK-------ATDNQMSPLSLPPRNSLGNSRRGQLGEKDLPHSLVDNDNYLNFSSLS---SGASPYKTCLSDGNPY--VSSALSVPASPRVARKMLLASTS---SDDFDRASYSGTSPSHSFLSGEPDRVLVARRNFSCGSMELDD---SDLESLRQSSETPQPILRERKSSISSISGRDDLMDYHRRQREERLREQEMERLERQRLETILSLCAEYTKPEGRRLSAGTTVADVQKINKELEKLQLSDEESVFEEALVCPDARYRCHRKGSLQDVDIAGFGSLGHS-ASFLAPRGSKNDELLGDLTRMPPPSSAAFLKATNESSYLSILPKTPEDMGEEQRTQELAAMEDARMVILNNLEELEQKIKDINDQMDESSRELDMECALLDGEQKSETAELMKEKEILDHLNRKITELEKNIVGEKTKEKVKLDAEREKLERLQELYSEQKTQLDNCPEAMREQLQQQLKRDADLLDVESKHFEDLEFQQLEHESRLDEEKENLTQQ-----LLREVAEYQRNIVARKEKISALKKQASHIVQQAQREQDHFVKEKNNLIMMLQREKENLCNLEKKYSSLTGGKGFPINPNTLKE---------------------------------------------GYISVNEINESCG-----NSMN-LSPSTQFPADADAAVTEP---ASAVPVSQPQSSEHQSAVCSGFMPPSTLSPSVTESSSAAWPEVMATPVDSFPLNDTPPPLPAKKHRRQQPQEQQHFRSLEERKKQHKEG-LYLSDTLPRKKTTPSLSPHFSSATMGRSTTPKAHLPLGQSNSCGSVLPHSLATMTKDA--ESRRILRG-----YNHQQMSEGQRQKP-EFYSRTASESNVYLNSFHYSDRSYKDQAYDTLSLDSSDSMETSISACSPDNISSASTSNIARIEEMERLLKQAHAEKTRLLESRERE-MEAKKRALEEEKRRREILEKRLQEETSQRQKLIEKEVKIREKQRAQ---ARPLTRYLPVRKEDFDLRSHVETAGHNIDTCFHVSITEKTCRGYLIKMGGKIKTWKKRWFVFDRNKRTFSYYADKHEAKLKGVIYFQAIEEVYYDHLKNANKSPNPLLTFSVKTHDRIYYMVAPSPEAMRIWMDVIVTGAEGYTHFLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K1N2-1", "uniprot_id": "PHLB2_MOUSE", "id": "Q8K1N2-1", "name": "Pleckstrin homology-like domain family B member 2", "aln": "-MAEDSHMQKQLEFQNGSLEEGF--VVRSLENEPQNMMES---LSPRKYSSSLKFKANG--DYSGSYLTLSQPVS---AKRSPSPMGTSVRSS---PSLAKIQGS----------KQF-CDGIDKN------------------------------ISMKPPISFLSSAASLGGYPLGKADLDHYTGRDSERSTR-----------LSEKPPYSRYSSRNKSHDSVYFLGGLEGRKTSGSLLTMWNGNS----------LSCTGSSPISR---SGAASMPSSPKQVRKMNLQDHSTLQPRLSRHKEPASENVS---VRTRKYSGSSLSNMGAYSR--------------------SLPRLYK-------ATDNQMSPLSLPPRSSLGNSRRGQLGEKDLPHSLVDSDNYLNFSSLS---SGASPYKTCLSEGNPY--VSSALSVPASPRVARKMLLASTS---SDDFDRASYSGTSPSHSFISGEPDRVLVARRNFSCGSMELDD---SDLESLRQSSETPQPVLRERKSSISSISGRDDLMDYHRRQREERLREQEMERLERQRLETILSLCAEYTKPEGRRLSAGTTVADVQKINKELEKLQLSDEESVFEDALVCPDARYRCHRKGSLQDVDVAGFGNLGHS-ASFLAPRGSRSDELLGDLTRTPPSSSAAFLKATNESSYLSILPKTPEDIGEEQRTQELAAMEDARMVILNNLEELEQKIKDINDQMDESSRELDMECALLDGEQKSETAELMKEKEILDHLNRKITELEKNIVGEKTKEKVKLDAEREKLERLQELYSEQKTQLDNCPESMREQLQQQLKRDADLLDVESKHFEDLEFQQLEHESRLDEEKENLTQQ-----LLREVAEYQRNIVARKEKISALKKQASHIVQQAQREQDHFVKEKNNLIMMLQREKENLCNLEKKYSSLTGGKGFPINPNTLKE---------------------------------------------GYISVNEINESCG-----NSTN-LSPSTQFPADADAAVTEP---ALAVPVSQPQSSE-------------------------------------------------------------HFRSLEERKKQHKEG-LYLSDTLPRKKTTPSLSPHFSSATMGRSTTPKAHLPLGQSNSCGSVLPHSLATMTKDS--ESRRMLRG-----YNHQQMSEGQRQKP-EFYSRTASESNVYLNSFHYPDRSYKDQAYDTLSLDSSDSMETSISACSPDNISSASTSNIARIEEMERLLKQAHAEKTRLLESRERE-MEAKKRALEEEKRRREILEKRLQEETSQRQKLIEKEVKIREKQRAQ---ARPLTRYLPVRKEDFDLRSHVETAGHNIDTCFHVSITEKTCRGYLIKMGGKIKTWKKRWFVFDRNKRTFSYYADKHEAKLKGVIYFQAIEEVYYDHLKNANKSPNPLLTFSVKTHDRIYYMVAPSPEAMRIWMDVIVTGAEGYTHFLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86SQ0-1", "uniprot_id": "PHLB2_HUMAN", "id": "Q86SQ0-1", "name": "Pleckstrin homology-like domain family B member 2", "aln": "-MEEHSYIQKELDLQNGSLEEDS--VVHSVENDSQNMMES---LSPKKYSSSLRFKANG--DYSGSYLTLSQPVP---AKRSPSPLGTSVRSS---PSLAKIQGS----------KQFSYDGTDKN------------------------------IPMKPPTPLLNTTSSLSGYPLGRADFDHYTGRDSERALR-----------LSEKPPYSKYSSRHKSHDNVYSLGGLEGRKASGSLLAMWNGSS----------LSDAGPPPISR---SGAASMPSSPKQARKMSIQDSLALQPKLTRHKELASENIN---LRTRKYSSSSLSHMGAYSR--------------------SLPRLYR-------ATENQLTPLSLPPRNSLGNSKRTKLGEKDLPHSVIDNDNYLNFSSLS---SGALPYKTSASEGNPY--VSSTLSVPASPRVARKMLLASTSSCASDDFDQASYVGTNPSHSLLAGESDRVFATRRNFSCGSVEFDE---ADLESLRQASGTPQPALRERKSSISSISGRDDLMDYHRRQREERLREQEMERLERQRLETILSLCAEYTKPDSR-LSTGTTVEDVQKINKELEKLQLSDEESVFEEALMSPDTRYRCHRKDSLPDADLASCGSLSQSSASFFTPRSTRNDELLSDLTRTPPPPSSTFPKASSESSYLSILPKTPEGISEEQRSQELAAMEETRIVILNNLEELKQKIKDINDQMDESFRELDMECALLDGEQKSETTELMKEKEILDHLNRKIAELEKNIVGEKTKEKVKLDAEREKLERLQELYSEQKTQLDNCPESMREQLQQQLKRDADLLDVESKHFEDLEFQQLEHESRLDEEKENLTQQ-----LLREVAEYQRNIVSRKEKISALKKQANHIVQQAQREQDHFVKEKNNLIMMLQREKENLCNLEKKYSSLSGGKGFPVNPNTLKE---------------------------------------------GYISVNEINEPCG-----NSTN-LSPSTQFPADADAVATEP---ATAVLASQPQSKE-------------------------------------------------------------HFRSLEERKKQHKEG-LYLSDTLPRKKTTSSISPHFSSATMGRSITPKAHLPLGQSNSCGSVLPPSLAAMAKDS--ESRRMLRG-----YNHQQMSEGHRQKS-EFYNRTASESNVYLNSFHYPDHSYKDQAFDTLSLDSSDSMETSISACSPDNISSASTSNIARIEEMERLLKQAHAEKTRLLESRERE-MEAKKRALEEEKRRREILEKRLQEETSQRQKLIEKEVKIRERQRAQ---ARPLTRYLPVRKEDFDLRSHVETAGHNIDTCYHVSITEKTCRGFLIKMGGKIKTWKKRWFVFDRNKRTFSYYADKHETKLKGVIYFQAIEEVYYDHLKNANKSPNPLLTFSVKTHDRIYYMVAPSPEAMRIWMDVIVTGAEGYTHFLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PXY1-1", "uniprot_id": "A0A8M9PXY1_DANRE", "id": "A0A8M9PXY1-1", "name": "Pleckstrin homology-like domain family B member 1", "aln": "MTDIVSAMDTEANCPASILEPESDQSFNSPKSPPLDLIDTGKGLKVQTATPHLVSLGSGRLSVAITLLPLKEGVTRIGRDDAPVPQDITIEGPGIEAEHCRIENSGGVVTLDPCGHLCSLDGVPVSRPTQLTQGYTLCLGKSYIFRFNHPEEANRMKSMLPQKSPVSPLVYSTDYLKFSSDFSHCLGGSGSRGMRSVSELRDLMDTLQKKKQALENSLRANGDSSPSYFSMTQSPPTTPNLLSPMTSSSPNSYQEQARRLYSSERPPFSTKVLPSTTSMPSSPRRSDPRERDTSLPYSRPMTRNQSQDSLLLNSSDSRRTATSGSALSMWNGSSTGATDPLPPAPGGGSGAASMPSSPRLARRFHTPESGRNGGLEPVPRQRKYSAGSLTGMSSHSRSLPRLYRPADSQLTLLPIYRSPDGHISHISGISDPNHQNGHSEVISISLSNTPGTKQPVAPPD---VTMTSGEATSPRQAKKVSLTSTSSYSEVDRQAMCGPSPALEIGLGERRQSFGKAGLGPPTGFRERKGSISSLSGKEELQDYHQRQRDERLREQEVERLERQRLETILNLCSGLGRAEQD--NTGLAVADLQKINKELEKLQVSDDDSTFSDSASLSAS------ISAENDYGIKFREPQAREERQVRQRKNSGHRDARSETTAVRGS-------APTPSPRLTRINKTTEDDT--QLKNDVRRIEEERIQVLNNMEELELKIKDLDNQMEESIRELEVERALLEGEQDSEMAQLQQEKDTLEQLKEKMAEIENKAQTDKSQDKAKLDAERVKLERLANLLAELKTQLDTCPEALKEQLQLQLCRDAETLEVETKRFEDLEFQQLERESRQDEEKESQTQH-----ILREIAEYQRSTVTRKEKLLALKKQCTQISQQAQRDKDSFVKEKNNLQMMLQREKENLVSLEKKYSELTGSLGFPVNPISMKEDCFQLADVCPPHSEFSHAHKTLSPLPADLLMFSSLLSSLTTKNAEGYVTVTELNELYSQLGVDSSPNPLPTQAQSSPDTPAMGTEPSPDPSPAESTAPPGEAELSPSSSPLSSSILSSSSFTACSHPNPKPPSVHWPEDMVTFLNPSPPPPPLPAKKMRRHRQHFRSLEERKRYGKEGGAHLSDTLPRKKTQPTITPQFTCATLGRNISPKSHPPLAQSSSCGSVLNRALAISPKETHMDTHRLHKGKSKKGRSQQHVGDEHRTRLSDLSGRASSQTNVYLDSIGYQD---NGRAFDTLSVDSSDSMDTSISACSPDNISSASTSNVLKIEEMERLLREAQAEKHRLLEYRERE-MESKSRALEEERRRREDLEKRLQEETTRRQKLIEREVKLREKQRAQ---SRPLTRYLPVRKDDFDLRAHIDSAGHNTETCYHISITEKTCRGFLIKMGGKIKTWKKRWFVFDRNRRTLSYYADKHEAKLKGVIYFQAIEEVYYDHLKSAHKSPNPSLTFSVKTHDRVYYMVAPSPEAMRIWMDVIVTGAEGYTQFMI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VX80-1", "uniprot_id": "Q9VX80_DROME", "id": "Q9VX80-1", "name": "PH domain-containing protein", "aln": "--------------------------MSLTKKDPS--------LRVAASDPHLVSLGGGRLSTAVTIHYIHIGDT---TIGSAASCSISLNGSGVRPLHCTIYRS----------DANEVTLVPEK--------------------------DSRLLIDGAPILEETKLSQGAMITIGNSNYLRFNNPDEAQMMRSAMG-------SNERISMPQIDFTQSARQAHELSQSLELESFYESIINPINNPS----------TYELECPKVFS------SDLVTVNMPAKDVLGQKYASFARNLAENHRNEKQLNN----QYAKGVGSNGGYWNVPSN----------------------AAIYK----EQHQQQHQQAPQDLLTKVNNDRYDRYPKAGGLQIYSMNGVNSDINNGPAT----GNNSGTGGGAELEDMLKICTEYADRNNSMPSTHNVSSTSS-----ITSSPIVQNRIKTNGSLPRDKNKSPFPQQAGVASSANISL---LSSSSGYENVRLLGPNRVEINGQIHVPASAGDGGSSSGVSSNALAPTAAVRASHENLNQNHSATTGGKYVPQSPRTKIRTNCMSPKKDVSFGNAFALAISPPPLASSAVVSTSKPIPIPSMVKPPLAPKPPAPNQQRDYEQLFKSFERKQQQLDRMVPAKRS-------NKNINNLTLNLQSVESQTQSPKPSRKPAPAPRSIHLEQRQRRELIQRRKQLKRELAELPPSAGIEGLELKLGEQP-LAPSASPRLQLQALQNRVCRLEAQRNATRVMEENQQAKLKQSIEIKQDQLKKLRAMLKQKPN--NACLKEELQLVCESLESDRKTFEDLEFQYFEEESEHHASHEEFKRQEQRLMLEAELAALRIQIGPDEEEPGSPTSPGSTGSNLVNGVMSQSLFGSAELLCPKRRNQEDLMSKSVNENMFYN-HKIEANTSTPKR-----------------------------------------------LPLQLFEDLAG-----GSCEQISFNLSLQGDRFEVNPLERRVPSQDDIDRSCKVANDAPISASQG--------------------------------------------ASTKIFDSIMEIERNRKLLLAQQGHQVIEHERQKMYDLKKKSHDEARTQYLLSTQQSMEQQRQLESDANGGKDAKLFEKTELQKLNQKPGE-----PVDDQVQKIAGDKENNVQNRKSTGSSPTTTTTTTTG---GGTTPQQQRHSQPELEHHAIALGIGGGGSGGAGGANQMVARSPRPLSEANNCDATIEAPKFANGMDSSASPAVADNKRASSNSQDTASAGSGSGNSGSGGSTASDRKRVLPKHQRPLTRYLPIFSPDLNLRHHIETAGHQIDPCPHVFVDAHSCRGYLHKLGATFHAWSRRWFVLDRQRSALIYYSDKSERKPRGGAYFATIDEVYLDHLN-ASKSGRPHCTFIVKTKKRSYNLQAASDSAARIWIDAIITGAQGNLDY--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. . * . * ..* . : : : . :. . . ::... . . * . . . . . :: : . . : * .:: . . .. . : .:: .. * . . :.: : : . ::.:: . . : .* . . * . : : : * : . . :. :. . * . :: : . : . . : :... . .: :. . :: * :. .* : . * :..* :. : . . : :. ..: :. . .: . . :* . : : :: . . : .: . : : . : . . . . . : .. . : ... .: .** : *::. :: * . :* *. :.. : . : *: *:.:: .:* : : :: : : .:* : : :: *. *: . *: :* .: *: : * ******* :*.**. . .:*. .:: : *:* : . . :*: : .. . : .: . : . :* :*::*:* . . : . : . : *. : *. :.: ::: . .* : :. . . * . . . : .:*..:: : *:* . . * :.: :. ...: * . .: .::: . : :. .* :: :. : . . : : ...: . :*: .. *..: . : . * * :*: . : : : *::. . :.:* . .: . : : . . :::*. ********: . *::** *:::***: :.* *: : ::***:* *:*..:::*.:****:**:: :: **:** * * :* ** :*:*** ***: * ** .* ** ***:.* * : *.* .* ***:*.*:***:* .: ", "identical_positions": 136, "similar_positions": 385, "identity": "9.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3238", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29341-1", "uniprot_id": "PABP1_MOUSE", "id": "P29341-1", "name": "Polyadenylate-binding protein 1", "aln": "---------------------------MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELN-GKQIYVGRAQKKVERQTELKRKFEQMKQD----------RITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEG-GRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAP-PSGYFMAAIPQTQNRAAYYPPSQIAQLRPSPRWTAQGARPHPFQNMP-GAIRP------AAPRP-PFSTMR--------------PASSQVPRVMSTQRVANTSTQTMGPRP-AAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPS--LAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9EPH8-1", "uniprot_id": "PABP1_RAT", "id": "Q9EPH8-1", "name": "Polyadenylate-binding protein 1", "aln": "---------------------------MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELN-GKQIYVGRAQKKVERQTELKRKFEQMKQD----------RITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEG-GRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAP-PSGYFMAAIPQTQNRAAYYPPSQIAQLRPSPRWTAQGARPHPFQNMP-GAIRP------AAPRP-PFSTMR--------------PASSQVPRVMSTQRVANTSTQTMGPRP-AAAATAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPS--LAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11940-1", "uniprot_id": "PABP1_HUMAN", "id": "P11940-1", "name": "Polyadenylate-binding protein 1", "aln": "---------------------------MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELN-GKQIYVGRAQKKVERQTELKRKFEQMKQD----------RITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEG-GRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAP-PSGYFMAAIPQTQNRAAYYPPSQIAQLRPSPRWTAQGARPHPFQNMP-GAIRP------AAPRP-PFSTMR--------------PASSQVPRVMSTQRVANTSTQTMGPRP-AAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPT--LAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9H361-1", "uniprot_id": "PABP3_HUMAN", "id": "Q9H361-1", "name": "Polyadenylate-binding protein 3", "aln": "---------------------------MNPSTPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENG-SKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELN-GKQIYVGRAQKKVERQTELKRTFEQMKQD----------RITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEG-GRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAYLTNEYMQRMASVRAVPN------QRAP-PSGYFMTAVPQTQNHAAYYPPSQIARLRPSPRWTAQGARPHPFQNKP-SAIRP------GAPRV-PFSTMR--------------PASSQVPRVMSTQRVANTSTQTVGPRPAAAAAAAATPAVRTVPRYKYAAGVRNPQQHRNAQPQVTMQQLAVHVQGQETLTASRLASAPPQKQKQMLGERLFPLIQAMHPT--LAGKITGMLLEIDNSELLYMLESPESLRSKVDEAVAVLQAHQAKEATQKAVNSATGVPTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QB54-1", "uniprot_id": "PABPA_DANRE", "id": "F1QB54-1", "name": "Polyadenylate-binding protein 1A", "aln": "---------------------------MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMMTRRSLGYAYVNFQQPADAERALDTMNFDVIKGRPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYGFVHFETHEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAEMGARAKEFTNVYIKNFGEDMDDEKLKEIFCKYGPALSIRVMTDDSGKSKGFGFVSFERHEDAQRAVDEMNGKEMN-GKQVYVGRAQKKGERQTELKRKFEQMKQD----------RMTRYQGVNLYVKNLDDGLDDERLRKEFSPFGTITSAKVMMEG-GRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTSQYMQRMASVRAVPNPVLNPYQPAP-PSGYFMAAIPQAQNRAAYYPTSQLAQLRPSPRWATQGVRPQHFQNMPNAAVRP------SAPRPQTFNPVR--------------PAS-QVPRMMTSQRMG---SQAMGPRPAAAGAATGPAQVRGVPQYKYAPGVRNPQQHMPTQPQVPMQQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQNMHPS--LAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAKEAAQKSVPSP-AVPAV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B5DF80-1", "uniprot_id": "B5DF80_RAT", "id": "B5DF80-1", "name": "Polyadenylate-binding protein", "aln": "---------------------------MNPSDPSYSLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVYRDRTTRRSLGYASVNFQQLEDAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDRSIDSKTLYDTFSAFGNILSCKVVCDENG-SKGYGFVHFETQEEAERAIEKMNGMFLNDRKVFVGRFKSRRDRQAELGARAKEFTNVYIKNLGEDMDDERLQDLFSRFGPALSVKVMTDESGKSKGFGFVSFERHEDARKAVDEMNGKDLN-GKQIYVGRAQKKVERQTELKHKFGQMKQDKPKIEQVPQDRSVRCQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVTMEG-GRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLSNQYMQRMASTSAVPNPGINPFQPAQGLSGYFMTATAPTQNRGTYYAPNQTTQQGPSARGSAQGTRAHPFQNMS-SAIHP------SNTMP-SFSTSG--------------PTSSQAVR----HRTASTSTQMMGPHP-AAASTAAAPAARTVTQYKYTAGVRNPPQHLNTQPQVTTQRSAVSAQGKESLTVSMLASAPPQAQKQMLGEWLFSLIQAMHPA--LAGKITGMLLEIDNLELRHMLESPECLHTKVDEAIAVLQAHQAKETSQKAVSSVAGVPTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A233-1", "uniprot_id": "D4A233_RAT", "id": "D4A233-1", "name": "", "aln": "---------------------------MNSSDPGCPMASLYVGDLHPDVTEAMLYEKFSSAGPILSIRVYRDVITRRSLGYASVNFEQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRRSGVGNVFIKNLNKTIDNKALYDTFSAFGNILSCKVVCDENG-SKGHGFVHFETEEAAERAIEKMNGMLLNDRKVFVGQFKSRKEREAELGTRTKEFTNVYIKNFGDRMDDKTLNGLFGRFGQVLSVKVMTDEGGKSKGFGFVSFERHEDAQKAVDEMNGKELN-GKHIYVGPAQKKVDRHIELKRKFEQVTQD----------RGIRYQGINLYVKNLDDGIDDERLQKEFSPFGTITSTKVMTEG-GRSKGFGFVCFSSPEEATKAVSEMNGRIVATKPLYVALAQRKEERQAHLTNQYIQRMASVRSGPNSLINAYQPAP--SGYSVAAVPQTQNCAPCCP-SQIVQPSPSTRWTAQGARPHPFPNVS-GASHP------AAPKS-SFTTVR--------------PSSSHVPQVMAAQRITNTSAQTTGQRP-ALASSPATTPVRSIPQYKYATGVRNSQQHLNAQ---LVQQPSVCIQGQEPWTASTLGTAP-QEQKQMLGERLFPLIQAMHPT--LAG--TSQLLK-ECSEYDHQI---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JQF8-1", "uniprot_id": "PAP1M_HUMAN", "id": "Q5JQF8-1", "name": "Polyadenylate-binding protein 1-like 2", "aln": "------------------------------------MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALETLNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKVACDEKG-PKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAERGAWARQSTSADVKDFEEDTDEEATLR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P21187-1", "uniprot_id": "PABP_DROME", "id": "P21187-1", "name": "Polyadenylate-binding protein", "aln": "------------------------------------MASLYVGDLPQDVNESGLFDKFSSAGPVLSIRVCRDVITRRSLGYAYVNFQQPADAERALDTMNFDLVRNKPIRIMWSQRDPSLRRSGVGNVFIKNLDRAIDNKAIYDTFSAFGNILSCKVATDEKGNSKGYGFVHFETEEAANTSIDKVNGMLLNGKKVYVGKFIPRKEREKELGEKAKLFTNVYVKNFTEDFDDEKLKEFFEPYGKITSYKVMSKEDGKSKGFGFVAFETTEAAEAAVQALNGKDMGEGKSLYVARAQKKAERQQELKRKFEELKQK----------RHESVFGVNLYVKNLDDTIDDDRLRIAFSPYGNITSAKVMTDEEGRSKGFGFVCFNAASEATCAVTELNGRVVGSKPLYVALAQRKEERKAHLASQYMRHMTGMRMQQLGQIYQPNAAS---GFFVPTLPSNQR---FFGSQVATQMRNTPRWVPQVRPPAAIQGVQAGAAAAGGFQGTAGAVPTQFRSAAAGARGAQPQVQGTHAAAAAANNMRNTGARAITGQQTAAPNMQIPGAQIAGGAQQRTSNYKYTSNMRNPPVPQLHQTQPIPQQ--LQGKNSEKLIASLLANAKPQEQKQILGERLYPMIEHMHAN--LAGKITGMLLEIENSELLHMIEDQEALKAKVEEAVAVLQVHRVTEPAN------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04147-1", "uniprot_id": "PABP_YEAST", "id": "P04147-1", "name": "Polyadenylate-binding protein, cytoplasmic and nuclear", "aln": "MADITDKTAEQLENLNIQDDQKQAATGSESQSVENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELN-GEKLYVGRAQKKNERMHVLKKQYEAYRLE----------KMAKYQGVNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRKDVRRSQLAQQIQARNQMR---------------------------------------YQQATAAAAAAAAGMPGQFMPPMFYGVMPP-------------------------------------------------RGVPFNGPNPQQMNPMGGMPKNGMPPQFRNGPVYGVPP------------------QGGFPRNANDNNQFYQQKQRQALGEQLYKKVSAKTSNEEAAGKITGMILDLPPQEVFPLLESDELFEQHYKEASAAYESFKKEQEQQTEQA--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******** .*.*: *:: **. *.: ***: ** * * .** **::. ..:*:: :*: ::.: ************:.* **:*:*** *:.*::*: .*.**:***.::. **:* .**.*****: . *: :*. :***:** ::::*. . .:::*: : .. :*:: . :: ", "identical_positions": 75, "similar_positions": 70, "identity": "10.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3246", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JYE0-1", "uniprot_id": "A0A0G2JYE0_RAT", "id": "A0A0G2JYE0-1", "name": "", "aln": "MLKPQPPQQTSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLPATAAPPGPPTVVSPCLGPAAAAGSGLRRGAESILAAPAP--QQHQERPGAVAIGSVRGQTTGKGPPQSP-VFEGVYNNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGG---------PRREDIVDTMVFKPSDVLLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQR--------QGSGRESP---SLVSREGKYIPLPQRVRE--------GPRGGVRCSSS-RGGRPGLSSLPPRGPHHLDNSSPGPGSEARG----INGGPSRMSPKAQRPLRGGKTLSSPNNRPSG-EASVPPTSA------VGRMYPPRSPKSAAPAPVSASCPEPPIGSAVASS-ASIPVTSSVVDPGAGSISPASPKLS----LAPTDVKELPTKEPSRSLEAQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQ--PSSSSETGLDPFPSRILKEEAKGKEKEVDGLLTSDPMGSPVSSKAESILDK----EDKVPLAAVAGSEGPEQLQPPCPSQTG-SPPVGLIKG--DDKEEGP-----VTEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYIS--YIPQIHMGPAVQAPQ-MYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSS---YIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTS--------GSHPQAIVSSSTPQYP-SAEQPTPQALYATVHQSYPHHATQLHGHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTG-TPPSLPPGPSAQSPQSSFPQPAAVYAIHPHQQLPHGFTNMAHVTQAHVQTGVTAAPPPHPGAPHPPQVMLLHPPQGHG-GPPQGAVPPSGVP----------ALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRILCRVGRSHSRRRQGLAPGSVLCFPPSSLSCDPAAPLPTASPALSDPDCLLT------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TQH0-1", "uniprot_id": "ATX2L_MOUSE", "id": "Q7TQH0-1", "name": "Ataxin-2-like protein", "aln": "MLKPQPPQQTSQPQQPPPTQQAVARRSPGGTSPPNGGLPGPLTATAAPPGPPAAVSPCLGPAAAAGSGLRRGAESILAASAP--PQHQERPGAVAIGSVRGQTTGKGPPQSP-VFEGVYNNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGG---------PRREDIVDTMVFKPSDVLLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQR--------QGSGRESP---SLVSREGKYIPLPQRVRE--------GPRGGVRCSSS-RGGRPGLSSLPPRGPHHLDNSSPGPGSEARG----INGGPSRMSPKAQRPLRGAKTLSSPSNRPSG-EASVPPTSAALPFLPVGRMYPPRSPKSAAPAPVSASCPEPPIGSAVASS-ASIPVTSSVVDPGAGSISPASPKLS----LTPTDVKELPTKEPSRNLEAQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQ--PSSSPETGLDPFPSRILKEEAKGKEKEVDGLLTSDPMGSPVSSKTESILDK----EDKVPMAGVGGTEGPEQLPAPCPSQTG-SPPVGLIKG--DEKEEGP-----VTEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYIS--YIPQIHMGPAVQAPQ-MYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSS---YIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTS--------GSHPQAIVSSSTPQYP-AAEQPTPQALYATVHQSYPHHATQLHGHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTG-TPPSLPPGPSAQSPQSSFPQPAAVYAIHPHQQLPHGFTNMAHVTQAHVQTGVTAAPPPHPGAPHPPQVMLLHPPQGHG-GPPQGAVPPSGVP----------ALSASTPSPYPYIGHPQVQS---------------------------------------------HPSQQLPFHPPGN--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWM7-1", "uniprot_id": "ATX2L_HUMAN", "id": "Q8WWM7-1", "name": "Ataxin-2-like protein", "aln": "MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP-VFEGVYNNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGG---------PRREDIVDTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQR--------QGSGRESP---SLASREGKYIPLPQRVRE--------GPRGGVRCSSS-RGGRPGLSSLPPRGPHHLDNSSPGPGSEARG----INGGPSRMSPKAQRPLRGAKTLSSPSNRPSG-ETSVPPPPA------VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS----LAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQ--PSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDK----EDKPPLAPSGGTEGPEQPPPPCPSQTG-SPPVGLIKG--EDKDEGP-----VAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYIS--YIPQIHMGPAVQAPQ-MYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAG-PPLVAATPYSS---YIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTS--------GSHPQAIVSSSTPQYP-SAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTG-TPPSLPPGPSAQSPQSSFPQPAAVYAIH-HQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHG-GPPQGAVPQSGVP----------ALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIR-------------------EFSLAGGIWHGRAEGLQVGQDARVLGGE---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QA42-1", "uniprot_id": "F1QA42_DANRE", "id": "F1QA42-1", "name": "", "aln": "----MSFRRQNQPG-------------PGGRKTSNG---------------------------TSGS---------MASSVP--GSNSNRP-----NPGRNRNSVKTPSQSPPVFEGVYNNSRMLHFLTAVVGSRCDVMVKNGSLYEGIFKTLSSRCELAVDAVHKVKNEEGDGGGGGGTAVHPRKEEITDTMIFGPSDLVTMICRDVDLNYATRDTFTDSAIGS-SRLNGDHREKVLQRWDGGDSNGENFDLDADTANGWDASEMFRFNEETYGVKSTYDSSLSMYTVPLERGSSEGFRQREARAARLANEIEASSQYRHRVALENDEGRTDEDKFSAVVRDREREAAERERGRDSPGFSSAGSREGKYIP-PQRAREREMGVSGRGERGGAVSTLPNRTNRPGPSSSSPR-PLPSANSQALPPTDRNSS-LSVRGGFSTHQSQSSTPTQSRPSEPGHSSPPSP-HTLSHSLSHPQSLSDVARPVNGVSPKSQRTGQTNRNMRTSNSHSSPTVSRSPKPDAPPQDPLLTGSYLDPSSKPVGPTPLFPVDVNEILSKERMESPVGPQEGKSN-KIPSVQ--QRSQISEELRKFGNTFRLQQNPKTLPTESTQANPAHNTQTDPAAPTEAKPAPPTTPNTELSAEERSRETNPEGPVTSTPPPATSISAPSGIGMQNPPAEGQTAGAPQPARTPGSEDGKPEAPERSEGMTDQVKKSTLNPNAKEFNPTKAPLSMVKPSATPTPPRPTPPSPTVVLQTQPGQGAVYNPQYLS--YVSQVPIQIQGHSVQPQIPYSYMTAVS--QGKYPRTKGSVVTPRPD--HSSSAPPMIQAASAAG-PPLVASPYPPS---YLQYN--------QVIPAMPHYPGHQVYS-MLQGGPRMLGS--------GGHPQALGPPG-PQYPGQTEGPSAPQQGMYAPQSFSHHSGSIH---PQPSSTPTGSQPPPQHPAPSPGQSGQ-------SGPQPQSLYHSGPLSAPTPPNLPPGHSS--PQASYSLQG--YSLPGHQPLPHPYSSLGQLTQAHVPGALSG--PHHTGGHGPPPVMLLHAAPQQGSGPQHGPPPQQGAH----------QHFTYLGPQVPVQAHN---------------------------------------------------PQQIPYHPSGN--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8SWR8-1", "uniprot_id": "ATX2_DROME", "id": "Q8SWR8-1", "name": "Ataxin-2 homolog", "aln": "----MNNNSKRKTR-------------PTGGGASGG----------------------------------------ISRYNS--NDNSLRP----TNNKAGAGGGNGGAAVRPSAQGVYNNTFFMHSATALVGSVVEVRLRSGNIYEGVFRTFSGNFDIALELPACIKSKNLPE-----------EGKVPKHIIFPADTVVTIVAKDFDSQYATAGAFQTDGAISDKCNGARPDEKELEPWDSGANGDIDIELDS-AANGWDPNEMFRKNENTFGVTSTFDDSLASYTVPLDKGDSLEFKEAEAKAEKLAAEIENNPTCRDRLDLENGD---EEALFAAVER--------PSTEQDQRGDRGDRERNDRDREREERDRDRDRD-RGNKPRGAGDFQLRETMSSDRYITKQTRSITGPQLSHVGMSSQGSGRDRDTRGDGSMMMQSGGGSGQGGSTQSTAALMLAGGLKGVGPAPSANASADSSSKYSGGSMVKRKTVPQGGKVMRNNVPTGGSNVSVSQGGNGNSVGQNKGGYQPSMGMPS---QYSYQGNSQIMHGSSQYRNQSHMGGANKLNGDSNANTNKPLPQRQMRQYQGSQSNS-SLNYGGEPQSLGKPVHGSHGGHPGQNSNSPPLQTAGPQQQQQQQQQQQQQQQ---QQQPPQQQQHQNIQPQGQNTQPARQVRTRDNQMQELRQFGQDFQLAPSN--TSPPQQQQQQQQQQQQHQVQQQQQRALQQSASPPQQQQQQQQQQQHVVLHQVPQTHLHQAALSQPHYVPQQQPQQAPLPQQQHVPHHMQQKAQQQQLVETQHQHVQKQHQSQPQVQQPPPQLLQDPSQQPLPIYHTMPPPQTSPVVVTSPVLLEQPPPQPMPVVQQQQTQQLATPKPEVSPAPPSSNTTTPTGIASTPTAGVIASAGSEKTTPAAPTPTSNSATVPTGTAATAGGATGTTPVVKKHVLNPSAKPFTPR-GPSTPNPSRPHTPQTPVPMTNIYTT--TGGHVPPAANQPIYVMQPQHPFPPQTHPQAGQPPRLRRSNYPPMAAS-QMHVSASAATGQPLITAGPIPQFIQYGHAPHQQQFQSHTYAPMQMRVYPDQPQQLQFMTQTPQSTTPSPGQPHQQFHPPPQPSPAGGGPQPAFTPP-------TQAATYQLMCVHPQSLLANHYFPPPTPQHPQQNQQQYQIVMQQHQPQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53297-1", "uniprot_id": "PBP1_YEAST", "id": "P53297-1", "name": "PAB1-binding protein 1", "aln": "----MKGNFRKRDS--------------STNSRKGG------------------------------------------------NSDSNYTN----GGVPNQNNSSMFYENPEITRNFDD--RQDYLLANSIGSDVTVTVTSGVKYTGLLVSCNLESTNGIDVVLRFPRVADSG-----------VSDSVDDLAKTLGETLLIHG--------------------------------------------------------EDVAELELKNIDLSLDEKWENSKAQETTPARTN---------IEKERVNGESNEVTKFRTDVDISGSGREIKERKLEKWTP---------EEGAEHFDINKGKALEDDSASWDQFAVN--------EKKFGVKSTFDEHLYTTKINKDDPNYSKRLQEAERIAKEIESQG---TSGNIHIAEDRGIIIDDSGLDEED--------------------------LYSGVDRRGDELLAALKSNSKPNSNKGNRYVPPTLRQQPHHMDPAIISSSNSNKNEN-------AVSTDTSTPAAAGAPEGKPPQKTSKNKKSLS--SKEAQIEELKKFSEKFKVP-----YDIPKDMLEVLKRSSSTLKSNSSLPPKPISKTPSAKTVSPTTQISAGK--------SESRRSGSNISQGQSSTGHTTRSSTSLRRRNHG---------------SFFGAKNPHTNDAKRVLFGKSFNMFIKSKEAHDEKKKGDDASENMEPFFIEKPYFTAPTWLN----TIEESYKTFFPDEDTAIQEAQTRFQQRQLNSMGNAVPGMNPAMGMNMGGMMGFPMGGPSASPNPMMNGFAAGSMG-MYMPFQP----------QPMFYHPSMPQMMPVMGSNGAEEGG------------------------------------------------------------------------------------------------------GNISPHVPAGFMAAGPGAPMGAFGYPGGIPFQGMMGSGPSGMPANGSAMHSHGHSRNYHQTSHHGHHNSSTSGHK-------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .* ... . . . . ... : : : :** * : .* * *:: : . . .:: . . : . : : : :. :: .: .::.* : *.* . . :: * : . * : :... .* : :. : : : . . .. : *. . . . . .. . . . .: : . .: .::::: : . . : . . : . . . :. : :. : . :. . : : . . . . . : * : .: * . : : . . . .* * . . . : . . : . * ", "identical_positions": 19, "similar_positions": 137, "identity": "1.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3250", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50416-1", "uniprot_id": "CPT1A_HUMAN", "id": "P50416-1", "name": "Carnitine O-palmitoyltransferase 1, liver isoform", "aln": "MAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPSSWLIVVVGVMT-TMYAKIDPSLGIIAKINRTLETANCMSSQTKNVVSGVLFGTGLWVALIVTMRYSLKVLLSYHGWMFTEHGKMSRATKIWMGMVKIFSGRKPMLYSFQTSLPRLPVPAVKDTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAMDLLYILPTHIQAARAGNAIHAILLYRRKLDREEIKPIRLLGSTIPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPREMEQQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEEGYRSEDPDTSMDSYAKSLLHGRCYDRWFDKSFTFVVFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTANLLANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKDMGKFCLTYEASMTRLFREGRTETVRSCTTESCDFVRAMVDPAQTVEQRLKLFKLASEKHQHMYRLAMTGSGIDRHLFCLYVVSKYLAVESPFLKEVLSEPWRLSTSQTPQQQVELFDLENNPEYVSSGGGFGPVADDGYGVSYILVGENLINFHISSKFSCPETDSHRFGRHLKEAMTDIITLFGLSSNSKK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97742-1", "uniprot_id": "CPT1A_MOUSE", "id": "P97742-1", "name": "Carnitine O-palmitoyltransferase 1, liver isoform", "aln": "MAEAHQAVAFQFTVTPDGIDLRLSHEALKQICLSGLHSWKKKFIRFKNGIITGVFPASPSSWLIVVVGVIS-SMHTKVDPSLGMIAKINRTLDTTGRMSSQTKNIVSGVLFGTGLWVAIIMTMRYSLKVLLSYHGWMFAEHGKMSRSTRIWMAMVKVFSGRKPMLYSFQTSLPRLPVPAVKDTVSRYLESVRPLMKEGDFQRMTALAQDFAVNLGPKLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPIMVNSNYYAMEMLYITPTHIQAARAGNTIHAILLYRRTVDREELKPIRLLGSTIPLCSAQWERLFNTSRIPGEETDTIQHVKDSRHIVVYHRGRYFKVWLYHDGRLLRPRELEQQMQQILDDTSEPQPGEAKLAALTAADRVPWAKCRQTYFARGKNKQSLDAVEKAAFFVTLDESEQGYREEDPEASIDSYAKSLLHGRCFDRWFDKSITFVVFKNSKIGINAEHSWADAPIVGHLWEYVMATDVFQLGYSEDGHCKGDKNPNIPKPTRLQWDIPGECQEVIETSLSSASFLANDVDLHSFPFDTFGKGLIKKCRTSPDAFIQLALQLAHYKDMGKFCLTYEASMTRLFREGRTETVRSCTTESCNFVLAMMDPTTTAEQRFKLFKIACEKHQHLYRLAMTGAGIDRHLFCLYVVSKYLAVDSPFLKEVLSEPWRLSTSQTPQQQVELFDFEKYPDYVSCGGGFGPVADDGYGVSYIIVGENFIHFHISSKFSSPETDSHRFGKHLRQAMMDIITLFGLTANSKK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PEG9-1", "uniprot_id": "A0A8M9PEG9_DANRE", "id": "A0A8M9PEG9-1", "name": "carnitine O-palmitoyltransferase", "aln": "MAEAHQAVAFQFTVTPDGIDLHLCHEALRQIYLSGIHSWKKRFIRFKNGVMTGVYPGSPSGLVVVLVGYMSSTKYAKIDPSLGILTKLSTHLPVSKYITEDGQRIVGGVLVGTGLWIAVTFVMRNALKYLLSWHGWMFNQHGTLSLKTKIWLVLVKLFSGPKPMLYSFQSSLPRLPVPPVKDTVRRYLESARPLMDDEQYKRMEGLAKDFEKNLGPKLQWYLKLKSWWTSNYVSDWWEEYIYLRGRSPIMVNSNYYAMDFLYVNPTSLQAARAGNSIHAMMMYRRKLDRAQIKPLYLLENRVPLCSAQWERMFNTCRIPGLETDVLQHVNESKHIAVYHKGRFYKVWMFYDGRLLLPREIEQQMERILADKSEPQPGEEFLAALTAGDRVPWAKARSQFFIRGKNKQSLDAVEKAAFFVTLDDSEQRYEPDNPIQSLDSYGKSLLHGKCYDRWFDKSLNLIVFKNGTMGLNAEHSWADAPIVGHLWEQVLSSDPVRLGYTEEGHCKGNPHPNMPGPQRLQWDIPEECQTVISSSLKVANTLADDVDMHIFPFNDFGKGLIKKCKTSPDGFIQLALQLAHFRDKGKFCLTYEASMTRLFREGRTETVRSCTNETCAFVHAMMDEKATREERLKLLKAATEKHQNLYKLAMTGKGIDRHLFCLYLVSKYLGEDSPFLKEVLSEPWRLSTSQTPLQQMELFDLKKHPEYVTSGGGFGPVADDGYGVSYIILGEDLINFHISSKHSSHETDSHRFGSNIKQAMLDILDLFQLDIKPNKK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********************:*.****:** ***:*****:*******::***:*.***. ::*:** :: : ::*:*****:::*:. * .: ::.: :.:*.***.*****:*: ..** :** ***:***** :**.:* *:**: :**:*** ********:********.***** ***:*.****.: :::** .**:** .***:***********::****************.*:*********::**: ** :*******:***:::***.:** ::**: ** . :*********:***.**** ***.:**:.:*:**.***:**::***:::***** ***:****::** :.******* ******.******:.*. :* *********************::*: *. ::* *:***.******:*:*******:.::****..:*:************.**** *:: * .:***:*:*****: :**:* * ******* *** **.:**. *. **:***:* *** ****:****:****.*:********::* ***************************.*:* ** **:* * *:*:**:* * ****::*:***** **********:*****. :******************** **:****::: *:**:.*****************::**::*:******.*. ******** ::::** **: ** * :.:* ", "identical_positions": 521, "similar_positions": 179, "identity": "67.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3251", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P53036-1", "uniprot_id": "SAP4_YEAST", "id": "P53036-1", "name": "SIT4-associating protein SAP4", "aln": "--MSLWPFGETLS-HSGIDSILEEYYLIFRSLE-----------------------------------GNETSST----------DDKKN-------EPSMESE----SEFGTESRDRSDLN-------------------QSFIDRILLETALLDELNGAANDRLVDFICLGYFYDDRS-QQVRHMDYLVDMLMAYLKDIDRTG---------YRTPFLLENS----------------------------------------FHQTGEYEDQDDEDPMLYVN---IISSIFCSKSAPIVEALVQNTPFLSSLFEVFQFENIEAENCPILAVFLKINETLLFEQTSS-----------YLEFFKSQPNIVDKFLYHIEVSPLVEFLIKIMLTDQVESP-TNIIDFLYHQDLIPKCLNLLENSKYSPGIQNSSGELLKALISISTNFKLDTLW--------IGPNRLTRQLASPQYVDQLINIILFQR--GHAMGVAVSIIIELIRKNNSDYDEVDLLSTTIVDNPPSQRDPVYLGHLLYELTMHMEDFYALLIKLENDDDDDHDTASKALPSVKHHLLENQLHESFRP-LGFERVKITELISEMLHCSNMGLMNSKRGEKIARTRDKCR-DTLDQNSLEKAMKNLNINDNTITSNTL------------EDKCNNNDSNDSNDNQKQKKNIKKKFHDNELYSTFDTSDDNIDDDDDMSFEIPYVS-----------------------ETQNLKIRKNPTIGDLFKIKLHDLGFFPKFLQLFLRYPWNNFWHNIVFDIIQQIFNGRMDFSYNSFLVYSLFDFKKSTRFIPKPLYGSNQ-----------KLPVKDFHIISDFILQGHKDSFEFYEKEKTNLGYMGQLVLIAEEIAKYS----KIYKTDLIAPDIYAFLQDEVWMSYSSDILNETRTMCSIILG---------------------------GGQFCAESDENTNQDFLEKADMSKPAHPSTMDENEIVHEEDVKLHDK--------------------VAELIDELGQLTELDIHDKIKDVIVD-------------------------HHSDLN---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P43612-1", "uniprot_id": "SA155_YEAST", "id": "P43612-1", "name": "SIT4-associating protein SAP155", "aln": "--MSFWPFGQNLN-HSNINKILDEYFHVLHELERINPSVGKAIPAIFNNVQERGTSDSLDSIPEEYSHGDEVKTARGDQKSRFEKDDQQERYEKEEEERSMNSSESSTTSFSSGSTSKTDLDEEDISNATAPMMVTTKNLDNSFIERMLVETELLNELS-RQNKTLLDFICFGFFFDKKTNKKVNNMEYLVDQLMECISKIKTATTVDLNNLIDYQEQQQLDDSSQEDVYVESDTEQEEEKEDDNNSNNKKRRKRGSSSFGNDDINNNDDDDDANEDDESAYLTKATIISEIFSLDIWLISESLVKNQSYLNKIWSIINQPNFNSENSPLVPIFLKINQNLLLTRQDQ-----------YLNFIRTERSFVDDMLKHVDISLLMDFFLKIISTDKIESP-TGIIELVYDQNLISKCLSFLNNKESPADIQACVGDFLKALIAISANAPLDDIS--------IGPNSLTRQLASPESIAKLVDIMINQR--GAALNTTVSIVIELIRKNNSDYDQVNLLTTTIKTHPPSNRDPIYLGYLLRKFSNHLSDFFQIILDIENDAN---------IP-----LHENQLHEKFKP-LGFERFKVVELIAELLHCSNMGLMNSKRAERIARRRDKVR-SQLS-HHLQDALNDLSIEE--------------------KEQLKTKHSPTRDTDHDLKNNNGK--IDNDNNDNDDESD--YGDEIDESFEIPYIN-----------------------MKQNIKLRTDPTVGDLFKIKLYDTRIVSKIMELFLTHPWNNFWHNVIFDIIQQIFNGRMDFSYNSFLVLSLFNLKSSYQFMTDIVISDEKGTDVSRFSPVIRDPNFDFKITTDFILRGYQDSYKFYELRKMNLGYMGHIVLIAEEVVKFS----KLYKVELISPDIQVILQTEEWQYYSEEVLNETRMMYSKILG---------------------------GGSYIDDGNGNIIPQLPDNTTVLTPNGDASNN-NEILDSDTGSSNGTSGG------------GQLINVESLEEQLSLSTESDLHNKLREMLINRAQEDVDNKNTENGVFILGPPEDKNSNSNINNTNHNSNNSNNNDNNDNNDNDNDNTRN-----YNEDADNDNDYDHE-----------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40856-1", "uniprot_id": "SA185_YEAST", "id": "P40856-1", "name": "SIT4-associating protein SAP185", "aln": "MSGSFWKFGQDFGSQSPLAKLLNRAFIKID-----DKPTSTEAGKIDSN-----------------STDESLESNS------FKSEDEEEEYELPNREEDYKAYKPNLSLLNDLLDDEELYTELMCSN-------------FKLLVYLKYPEVLSKLIDYVRNSTILESNIDRVTSEDRDLVRGEDKDTTEDFENAKADKKNIDGTFEEKERTRSGEEEELENEENDS------------------------------------ASEDTRVTLPHELEEHDDTRRARIAAEILSADVWPISSALIENEGLLAKLWSILRLP--SPLSIEASTYFMKINERLLDMNMDG-----------IIEFILKKEHIVDDFLAHIDNPPLMDFLLKVISTDKPEIS-NGVIQLFKKQNLVPKLIHLLD-PVFDSCTQSAAGDFLKALVTISGNCPNEITSS-------IGPNELTRQLVSPNMMKQLMDIMLKG---GNSLNNGVGIIIELIRKNNSDYDTIQTNYTTIESHPPTDRDPIYLGYLVKMFSEHMADFNKILTEKK-------------IP------LLQTSYGTIEP-LGFERFKICELIAELLHCSNMTLLNEPSAYDIVRERDAERERIFNSQNYVDSNDRSELKENEDDNTGD------------ADDEVEDDTNQVESANTSIDGEEVIDKLNSLQIETNKVNQNMNNEEQHSLMPDFNNGDFKDEEDENPFEPQYSDVILDSSDIEKNFRVSPNVGDQLKISLQDTRVIDTMLEMFFHFQWNNFLHNVVYDVVQQIFNGPLKIGYNRFLLDDLLINIR----------------------------------LTDMIINGNNECIEYEKGHDTRLGYMGHLTLIAEEVTKFTA-YIEEMNITFENTEVMSSLFESKWIAYTEDVLEDLKEKYNAILGDIAEEGDMLQDEEEDAVYDKGERTMGTVDDYINDIMQMDNVRCQEEEEDEGEGYVSFDEDEPQEYRNGDSVRSKESNSSEGKRDQEQLYYEYVNEDGTKTRLNFNPDSDATEQVPGEVNRDHKIPLKLKRSFTDACKSETIPNNTVNAKEESVFQFSNELSDGWESSPSNSIPKRASP-----SKNGMNSP-MFQHQFELHSP--TDEFGGHKDEILSAEGHDYDIDEYDELSD-------DSDEEYDNCEDEDSLDYADSAAYALCRSKSKDKISWDEEEQARLMGVVKFNSEHYRD------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P36123-1", "uniprot_id": "SA190_YEAST", "id": "P36123-1", "name": "SIT4-associating protein SAP190", "aln": "MSGSFWKFGQDYSIESPVSKILNSAFIKINKDQDDDVPTGTCEENIADD-----------------EDNSSHDYAASEDNVVNENEEKEEENTLPTTESEYENYRPNLDVLDDLLDDDELYTELMCSN-------------FKLLIFLKYPDVLSKLIEYVTNEKILDEETD--SAKKPEIIEGVN-DHPILIERDRKDKKEDAEEGGDSEETTNDSDHDS-GDERSV------------------------------------DSEETSITLPPESEEQVETRRARIAAEILSADVWPISAAIMQNKDLLGRLWSILDHP--APLPIPASTYFMKINERLLDMDITG-----------MLEFILSRDSLVARFLTHVDNPSLMDFLLKVISTDKPDSP-TGVIKILKSQELIPKLLDHLN-PEYGISTQSAAGDFIKAFVTLSTNSSNELASG-------IGPNELTRQLVSEEMIEKLIKIMLKG---GTSLSNGVGIIIELIRKNNSDYDFIQLVYTTLESHPPTDRDPIHLIHLVKLFAKHMPDFADMLDKTK-------------LP------LMEMPFGNIEP-LGFERFKICELIAELLHCSNMTLLNEPNGEMIAQERDIERAKELETS--TEKENITAIVDNK--SSYY------------DKDCVEKDITENLGALQINNQGSEEDELNDTGVSSVKLDVKSDAKVVEGLENDASG------------VELYDETLSDTESVRECLREKPLVGDRLKIALEDTKILISILDMFTEFPWNNFLHNVIFDIAQQIFNGPLKTGYNRFLLKDYLVDAY----------------------------------LTKKIVDADKACQDYEKKTGLRYGYMGHLTLVAEEISKFKE-YIDEMKLTFCNTAVSDRLEEPFWKEYSETILADTREKYNTVLGDFGND----QESDDDVIRNSDS------EDIIGDTEGNENYGNGENDELLSNGHDSGNMDLYYNFNNNENEENEED------------YAEYSDVDNKNYYNNVETNDDDYDSDDGKSK-------SAESEFTDKISEHRDGNSLYNEDND--ENGSDKWTSGTSLFPPDHFPSRSQP-----SDPKLQDQNIFHHQFDFEGVGDDDDYMDPNDDGQSYARPGNPLYTTPKTPPRPKTILFNSLSALDNNGEDEEVALGTSVDDRMDNEISSDEEDSEDEDEENDMGNEEGYSLYRSRSKEAF-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q922D4-1", "uniprot_id": "PP6R3_MOUSE", "id": "Q922D4-1", "name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "aln": "---MFWKFDLHSS--SHIDTLLEREDVTLK----------------------------------------------------------------------------------ELMDEEDVLQECKAQN-------------RKLIEFLLKAECLEDLVSFIIEE------------------------------------------------------------------------------------------------------------PPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNE--SPLNPLLASFFSKVLSILISRKPEQ-----------IVDFLKKKRDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQDVLNWLNEERIIQRLVEIVH-PSQEEDRHSNASQSLCEIVRLSRDQMLQVQNS-------TEPDPLLATLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACSVN----KSVLEAIRGRLGSFHELLLEPPKKS------------------VMKTTWGILDPPVGNTRLNVIRLISSLLQTN-TSSINGDLMELNSIGVILDMFFKYTWNNFLHTQVEICIALILASPFEN------------AENGTIT---DQDSTGDNLLLKHLFQKCQLIERILEAWDTNEKKQAEGGRRHGYMG---------------------HLTRIANCIVHSTDKGPNSALVQQLIK----DLPDEVRERWETFCTNSLGETNKRNTVDLA-----------------------------------------------FSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIALFEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRS-----SSGSTDSEESTDSEEEDGAKQDLFESSSANTEDKMEVDLNEPPTWSANFD-VPMET-THGAPLDSVG--------SDVWSTEEPMPTKETGWASFSEFTSSLSTKESLRSNSPVEMETSTESVDPLTPGAAA--------LATQPEAPGSMAMEASSDGEEDAESTDKV-----TETVMNGGMKETLSLTVDAKTETAVFK------SEEEKLSTSQDAACK-------DAEET--------------PEPAEAKCTAPL----TPSSSPEQRTDQPSMPSDPSVNGPV------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1MAH5-1", "uniprot_id": "F1MAH5_RAT", "id": "F1MAH5-1", "name": "", "aln": "---MFWKFDLHSS--SHIDTLLEREDVTLK----------------------------------------------------------------------------------ELMDEEDVLQECKAQN-------------RKLIEFLLKAECLEDLVSFIIEE------------------------------------------------------------------------------------------------------------PPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNE--SPLNPLLASFFSKVLSILISRKPEQ-----------IVDFLKKKRDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQDVLNWLNEERIIQRLVEIVH-PSQEEDRHSNASQSLCEIVRLSRDQMLQVQNS-------TEPDPLLATLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACSVN----KSVLEAIRGRLGSFHELLLEPPKKS------------------VMKTTWGILDPPVGNTRLNVIRLISSLLQTN-TSSINGDLMELNSIGVILDMFFKYTWNNFLHTQVEICIALILASPFEN------------AENGTIT---DQDSAGDNLLLKHLFQKCQLIERILDAWDTNEKKQAEGGRRHGYMG---------------------HLTRIANCIVHSTDKGPNSALVQQLIK----GLPDGVRERWEAFCTDSLGEANKRNTADLVTTCHIHSSSDDEIDFKDTGFSQDSSLQQA------------------FSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIALFEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRS-----SSGSTDSEESTDSEEEDGAKQDLFESSSANTEDKMEVDLNEPPTWSANFD-VPMET-THGAPLDSVG--------SDVWSTEEPMPTKETGWASFSEFTSSLSTKESLRSNSPVEMETSTEPVGPLTPGAAA--------LASQPEAPGSVAMEASSDGEEDAESTDKV-----TETVMNGGMKETLSLTVDAKTETAVFK------SEEEKLSTSQDAACK-------DTEET--------------PESAEAKCTAPR----TPNSSPEQRTDQPSMPGDTSVNGPV------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5H9R7-1", "uniprot_id": "PP6R3_HUMAN", "id": "Q5H9R7-1", "name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "aln": "---MFWKFDLHSS--SHIDTLLEREDVTLK----------------------------------------------------------------------------------ELMDEEDVLQECKAQN-------------RKLIEFLLKAECLEDLVSFIIEE------------------------------------------------------------------------------------------------------------PPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLND--SPLNPLLASFFSKVLSILISRKPEQ-----------IVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQDVLNWLNEEKIIQRLVEIVH-PSQEEDRHSNASQSLCEIVRLSRDQMLQIQNS-------TEPDPLLATLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACSVN----KSVLEAIRGRLGSFHELLLEPPKKS------------------VMKTTWGVLDPPVGNTRLNVIRLISSLLQTN-TSSINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFEN------------TENATIT---DQDSTGDNLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMG---------------------HLTRIANCIVHSTDKGPNSALVQQLIK----DLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDSSLQQA------------------FSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIALFEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRS-----SSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEPPNWSANFD-VPMET-THGAPLDSVG--------SDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAA--------LAVQPEAAGSVAMEASSDGEEDAESTDKV-----TETVMNGGMKETLSLTVDAKTETAVFK------SEEGKLSTSQDAACK-------DAEEC--------------PETAEAKCAAPR----PPSSSPEQRTGQPSAPGDTSVNGPV------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AWD3-1", "uniprot_id": "A0A8M3AWD3_DANRE", "id": "A0A8M3AWD3-1", "name": "", "aln": "---MFWKFDLHST--SHIDTLLEKDDVTLT----------------------------------------------------------------------------------EVMDEEDVLQECKAQN-------------HKLVDFLVRPQCMEDLVVYITQE------------------------------------------------------------------------------------------------------------PNDDVEEKIKYKYPNISCELLTSDVGQINDRLGEDESLLMKLYSFLQNE--PPLNPLLASFFSKVLSILIGRKPEQ-----------IVEFLRKREDFVDLMIKHIGTSAIMDLLLRMLTCIEPQQLRQDVLNWLNEEKVIQRLVDMVQ-PSQDEDRHSNASQSLCEIIRLSRDQMFQVQGS-------SEPDPLLATLEKQETVEQLLSNIFDKEKNESAIVSVIQILLTLFETRRPAFEGHLEICPPGMNHPSFSVN----QSILDAVRPRLKDFHQLLLEPPKKT------------------VLNTTWGVLDPPVGNTRLNVVRLVTSLLQTN-THIINQELIALNTLGVILDMYFKYLWNNFLHTQVEICTAMVLAMPSTQ------------SESPEINRENDQEPIRENILIKHLFQKCQLIQRILDAWGSNDKEQTEGGRRRGYMG---------------------HLTRIANSIVHNSDKGPNGSQIQQLISGLSIELPEEDRERWEAFTSGQLADTNKKNTVDLVNTHHIHSSSDDEVDFKDSGFHQDSSLQQA------------------FSDYQMQQMTSNFIEQFGFNDEEFADQDDVGDIPFDRISDINFSLNTNESANVALFEACCKEKIQQFEDAGSDEEDIWDEKDVTFAPEAPRRPR----SSGSTDSEESTDSEEEDG-KRDPFESTNATSDDRMEVDSGDGTVWTANFDDIPMDTGSSTAPSAPVSNSTASVPESTGWSSPNASGDGETGWADFSSFTP-VSPKDPLRCNSPVAMETSIETVDPLGVNAPMQQENTDQWLPNETTPTSPRGKTGDASDPEEEPVSDRI-----TETVTNGSMKETVSLTVDAKTETAVFKRVLKSYREEEKQSTSEDASAKLFVAESGDAEKSNCPSSNCQKPGLKHLEKAKSPCEALNGPLEDAADMDEAKSEQCTANPEAAVNGPA------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PEH8-1", "uniprot_id": "M9PEH8_DROME", "id": "M9PEH8-1", "name": "", "aln": "---MFWDKGYAPS--ANIEALLEKENSTLE----------------------------------------------------------------------------------EFLDEEDILQECKTQK-------------KNLVNYFTRPEVIRRLVELITTE------------------------------------------------------------------------------------------------------------PSEDVPMSKRFRYANMSCEILTLGLPSLDEKLLNDAETLQLLYSYLEKE--PPLNPLLSSFFSKTFSMLFTKKPEQDWFLYQHMCLQLLEYIKSQKTFLDFICKHFDTPVIPDLIMQMMKDIEGGRLKRNLFEWLTEDKIVERLIAILR-NPQETDKHANVADFFCDLINQGRLMRQTEQENDSFEPAFDGSNPILKTIEFADTIEALLNVILEPNAQESAILSGISVVLTLIKP-ITFTDEPNSDRQRLLQKREREIHQEVQETVITVMAPRLQEFVHILKNPPAKP------------------TLETTAAVLTPPFGKTRLQVCRVFTALLETK-HETIQQAICATEYFSLLLDFFKQYCWNNFLHTEMEKALYVVFYNELSNNNTASTEVTDYFTADCLINAFLKVGTEESEVEMKNALNDAKRAEGGKDEEGGDIEIEVAAAQEVAAQTPD-----ERQTAAEENQEHEEHMSQVEAAAEATASEDAEPKAQDNEVKNSEVDGESPTDQQESEATLNDLDKTKTVPSPPPSEMQSHLIVNCHLISKLVDLWQHNAQAQSAEK----------------GRRLGYMGHLIKILRHITNCISESEHIGDLITSSLSDEDEVKLWQSLIDAETGEFSLAVKQQTKLLADCNPHEENQYNDGSNDYTGEINAWNVGNLPYREVDCSELNNTLQDIFFAIDQNRFQFGRNIDDEDDDDDEHGDHSGGGDGHGHGMFTKNSNTLNNLADPWDIQFAVLSSAPTQVNTGTANWGTDFNSDNFADFDAHFSTFGSDLGMPISAPPGEEEEEDSSPAPESATQVNPEEERQPAESIGLAVGKGVQDNLACTDDQQAEYDNNANVEKAISDKLAESSVVETAAIVTRLQSVLLDGEDDYEDDEGMWTKPLGADRPSETEQITPISNGPDSKVNELGLPFSNHANDISSNNVDGHEANITTEQQKLAAAAKTNNVEIATTTT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . : : :*: : . .:: : : : . : : ..:: : : :: * ::. : . . * * . *: :::: .. :: : *. . : ::::::: : .::. . : :: : : : : .: : :: . .: : : : : *:. :: :: : ::: *:. . : : . . :: . :: .* :: . : : * .* *.:: .:.: :*. . :: . . : . . . . . . : . . : : . : . . : . . : : : . . ", "identical_positions": 14, "similar_positions": 144, "identity": "1.12%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3255", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AIG5-1", "uniprot_id": "A0A8I6AIG5_RAT", "id": "A0A8I6AIG5-1", "name": "", "aln": "MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAAVAAAVASGGKSGGGGCGGGGGYSASSS----SAAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRTNIKRKTFKVDDMLSKVEKMKGEQES-------HSLSAHLQLTFTGFFHKNDKPSQNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVSEELPARRKRN---REDGE--KTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPIS---KKRATWETILDGKR--LPPFETFSQGPTLQFTLRWTGETNDKSTAPVAKPLATRNSESLHQENKPGSVKPAQTIAVKETLTTEMQTRKEKDTSNETRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSR-NGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVTKLR-------------------------------------------------------------------------EMQQKLEKGESAAPANEDIAEEQNGTANGFSETNSKEKALETDGVSGVPKQSKKQKL----------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80U70-1", "uniprot_id": "SUZ12_MOUSE", "id": "Q80U70-1", "name": "Polycomb protein Suz12", "aln": "MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAAVAAAAS-GGKSGGGGCGGGGSYSASSSSAAAAAAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRTSIKRKTFKVDDMLSKVEKMKGEQES-------HSLSAHLQLTFTGFFHKNDKPSQNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVSEELPARRKRN---REDGE--KTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPIS---KKRATWETILDGKR--LPPFETFSQGPTLQFTLRWTGETNDKSTAPVAKPLATRNSESLHQENKPGSVKPAQTIAVKETLTTELQTRKEKDNSNESRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSR-NGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVTKLR-------------------------------------------------------------------------EMQQKLEKGESATPSNEEIAEEQNGTANGFSETNSKEKALETDGVSGVPKQSKKQKL----------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15022-1", "uniprot_id": "SUZ12_HUMAN", "id": "Q15022-1", "name": "Polycomb protein SUZ12", "aln": "MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATAS-GGKSGGGSCGGGGSYSASSSSS--AAAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRTNIKRKTFKVDDMLSKVEKMKGEQES-------HSLSAHLQLTFTGFFHKNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRN---REDGE--KTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPIS---KKRATWETILDGKR--LPPFETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVKESLTTDLQTRKEKDTPNENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSR-NGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVTKLR-------------------------------------------------------------------------EMQQKLEKGESASPANEEITEEQNGTANGFSEINSKEKALETDSVSGVSKQSKKQKL----------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0R1D5-1", "uniprot_id": "SZ12B_DANRE", "id": "B0R1D5-1", "name": "Polycomb protein suz12-B", "aln": "MAPQKY---------------------SAQVMNSKAN-------------------------GAVYPSSGVSSLKKPKIEQLQADHELFLQAFEKPTQIYRFLRTRNLITPVLLHRTLTFMSHRNSRTNAKRKSFKVDDLLSSVEKMKGEPES-------PSLTSHLQLTFTGFFHKNVKPCQNSENEQNSVSLEVLLVKVCHKKRKDVSCPIKQVPTGKKQVPLNPDLSQTKPGAFPSLLVSSNEFEPSNSHMVKSYSLLFRVSHTGKRDPNGFISCEADENIDVKDEIPPRRKRNSSLRGDGETTETFVAQMTVFDKNRRLQLLDGEYEVSMQQIEDCPVS---KKRATWETILDGKR--LPPFETFSQGPTLQFTLRWTADPSDPSTAPVAKPLSTRNSDTSTTESRISTLRPAP-VAVKESVSTSMQSRIEHS-PCEPRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLSHSRFIFNYVPHPKGARIDVSINECYDGSYVGNPQDIHSQPGFAFSR-NGPVKRTAVTHILVCRPKRTKPSLSEFLESEDGEPEQQRTYVSGHNRLYFHSDSCMPLRPQEMEVDSEDERDPEWLQEKTTTQIEEFTDVNEGEKEVMKLWNLHVMKNGFIADNQMSQASMLFVEICGPHIIRRNLCRNFLLHLVNLHDFNLVTIATIDQAMARLK-------------------------------------------------------------------------EIEESFPELEAGQ-------ESLDATCNGHSLS------------LGFSLHGKCTKLES--------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NJG9-1", "uniprot_id": "SUZ12_DROME", "id": "Q9NJG9-1", "name": "Polycomb protein Su(z)12", "aln": "MAPAKKREKDSNPDGSAANGIIGLTHGAPDASNAGST-------------------------------VPPTAEGQVKLNGHQQEQELFLQAFEKPTQIYRYLRNRHETNPIFLNRTLSYMKERMSRNNKKRISFQVNSMLESITQKSEAVSQNYLHVIYDSLHEKLPARLDNESGEDLLQEQLLCEAGESVSVETTLYKITRSKRKDSTLDFQELLSKCSQIVYNP---KDRVGEHATISIPLQTMRPMG-EQHTLYKLLFRIKVLSPSTCN-----------DENAETPPNKRSR-----PNE--KMFGSELILYEKSS-GFITEGEYEAMLQPLNSTSIKSFSPKKCTWETMPDSYIPLSLTYDVYQQSPMLKFHLTLS---NEQLPEMISAPELQRYVQHLDAVAEMNYNNNNYNNNNNCSGLKNGSGGGNSTVCKTTPEHIQIVYNFMYSNNTRQQTEYTQELNCPWCGLDCLRLYALLKHLKLCHARFNFTYQPAGSGARIDVTINDAYDGSYAGSPYDLAGPSGSSFARTCGPVRRTSVTSLMVCRPRRQKTCLDEFLELDEDEISNQRSYITGHNRLYHHTETCLPVHPKELDIDSEGESDPLWLRQKTIQMIDEFSDVNEGEKELMKLWNLHVMRHGFVGDCQLPIACEMFLDAKGTEIVRKNLYRNFILHMCSLFDYGLIAAETVYKTVQKLQGLLSKYAAGQELMQRQREEQLKYWLDVGMHKKQEDPKTLKSPQKPAPPADQASTSSASTSGSGSGSSSMQPPKRMPAHLKRGSAASSPGVQSKGTENGTNGSNSSSSNSKNVAKKSADQPLSTLANTRERRSEYGQKRNVSGSRLAATPASKRKLSSKDNTVLNKRQRYSDGSPGTGIGNGHGGGSGSGANRNKSNNHSLPATSNNASSSSSNSKRAIARRRSTSERTKASGSTGGGAGGVRTRLSVPAKYERR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32832-1", "uniprot_id": "RSC7_YEAST", "id": "P32832-1", "name": "Chromatin structure-remodeling complex subunit RSC7", "aln": "------------------------------------------------------------------------------------------------------------MSDSEGGLASEVEHEKRSRSTSNRPNYAIDTEDLDIDENDENEDD----------------------DYREEEANEGVNEEEISDEEEQINKSGRNKRR--HVDEEEDLSEDKGVTRSRNRSKFKKPVFPGIDDAEENLNPLK-------------------------------------------------------------------------VVNEEYVLPDDPEGETKIT-------ADGDLLGGREFLVRTFTLTEKG----------------NRKFMLATEPARIVGFRDSYLFFQTHPNLYKFILNQTQKNDLIDRGVLPYSYRNRQIALVTARGVFKEFGAKIIRGGKHITDDYYASELR-------------------------------TKGNVIEGKLAGDPIDKSARALETMMYPASENGINPAKNQVEFFEHRPHG------HMSNSNIIASGSKLSSTNWLYQHSAACSRFN-------------SDLFYDRVKVLLVDQQGLRDAYTNILHIP----------------------ESTQSTTVLGWRRSKNDSPSDTSIVYETVIHDNDLNKPKTGLS-------------------------------------------------------------------------EIPKEIYEDVVDEDVLRAITEQQNFEKCNEYI-----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: **.. :* .: :: .: : . .. : : * : * :.**: .: : . : . : : .. : . : :.* : : ** : . :. : : .. .: .:. : . * : : .. : : . ::.: : . ..: : : : .: :*. .*.* * . :: . .. . : :* : . .:.: . : :. * ** *: :* .. . : ::. : : .:.:. .::::: . . :: . :* .: :: : :. * .: : . : . ", "identical_positions": 23, "similar_positions": 139, "identity": "2.4%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3256", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q561R1-1", "uniprot_id": "CENPT_RAT", "id": "Q561R1-1", "name": "Centromere protein T", "aln": "MADLSSPDGDPTIRTLLRHVLDTADSHTPRRRQSTQTNPQRRRSQTPYSKRQGSQRKTSTRKHSHGTGSVG--------RLARVQGHG--------HLEEQTPRTLLQNILLTAPESSTVMP--NPVVKPAQVPEVARPSRRGSSRGSLELQLPELDPPSTLAPGLKAPGKRKQK---LRLSVFQQEVNQQLP--------------------LPQEQR--GAADGSSLASSFNLSFVPSVQPQTVDRPGLARRRPVRRPVNIGAFLQNLE-------------------------------------------------------------------------------------------------NKSLTSALPGDSHRTPVAALPTDVVFEDTQPFSQPLAGCSLSVHHSLPN------------------------------------PSQTEVEDAERVVGPRTPSTGTRPQS----------------------------------------------------------------------------------------------------------------------QMSRAGFGASPLPFSEPQPQS--------PELREAVGSKEAEEPKDLEGSSGDEETSGMPASRELSSS--AQDLLLAEEPHQLFEPPPSPGVAAVSSE---SVPAKLPSRT--------------------------------------------------------------------------------------------RTAQPRHHQDPYKAGLSHYVKLFSFHTKMPVEKAALEMVEKCLDEYFQRLCNDLEVFAAHAGRKTVKPKDLELLMRRQGLVTDQVSLHVLVERYLPLEYRQQLIPCAFRGNSVFPAQ--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TJM4-1", "uniprot_id": "CENPT_MOUSE", "id": "Q3TJM4-1", "name": "Centromere protein T", "aln": "MADLSFSDGDPTVRTLLRRVLETADSRTPMRRRSTRINAQRRRSQTPYSNRQGSQTKTSARKQSHGARSVG--------RSTRVQGRG--------RLEEQTPRTLLRNILLTAPESSTVMP--DPVVKPAQVPEVARSSRRESSRGSLELHLPELEPPSTLAPGLTAPGKRKQK---LRLSVFQQEVDQGLP--------------------LSQEPRRSRSADVSSLASSFNLTFVLPGQPETVERPGLARRRPIRQLVNAGALLQDLE-------------------------------------------------------------------------------------------------DNSLASALPGDSHRTPVAALPMDVGLEDTQPFSQSLAAFSLSGKHSLPS------------------------------------PSRPGVEDVERVMGP--PSSGTRLQS----------------------------------------------------------------------------------------------------------------------RMSRSGPAASPSPFLEPQPPP--------AEPREAVGSNEAAEPKDQEGSSGYEETSARPASGELSSS--THDSLPAEQ------PPPSPGVAVLSSEPLESVTAKCPSRT--------------------------------------------------------------------------------------------QTAGPRRRQDPHKAGLSPYVKFFSFCTKMPVEKTALEIVEKCLDKYFQHLCNDLEVFASHAGRKIVKPEDLLLLMRRQGLVTDQVSQHVLVERYLPLEYRQQLIPCAFSGNSVFPAQ--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96BT3-1", "uniprot_id": "CENPT_HUMAN", "id": "Q96BT3-1", "name": "Centromere protein T", "aln": "MADHN-PDSDSTPRTLLRRVLDTADPRTPRRPRSARAGARRALLETASPRKLSGQTRTIARGRSHGARSVG--------RSAHIQASG--------HLEEQTPRTLLKNILLTAPESSILMP--ESVVKPVPAPQAVQPSRQESSCGSLELQLPELEPPTTLAPGLLAPGRRKQR---LRLSVFQQGVDQGLS--------------------LSQEPQ--GNADASSLTRSLNLTFATPLQPQSVQRPGLARRPPARRAVDVGAFLRDLR-------------------------------------------------------------------------------------------------DTSLA---------------PPNIVLEDTQPFSQPMVG-SPNVYHSLPC------------------------------------TPHTGAEDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAGEAEEVNAFALGFLSTSSGVSGEDE---------------------------------------------------------------------VEPLHDGVEEAEKKMEEEGVSVSEMEATGAQGPSRVEEAEGHTEVTEAEGSQGTAEADGPGASSGDEDASGRAASPESASS--TPESLQARRHHQFLEPAPAPGAAVLSSEPAEPLLVRHPPRP--------------------------------------------------------------------------------------------RTTGPRPRQDPHKAGLSHYVKLFSFYAKMPMERKALEMVEKCLDKYFQHLCDDLEVFAAHAGRKTVKPEDLELLMRRQGLVTDQVSLHVLVERHLPLEYRQLLIPCAYSGNSVFPAQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YX66-1", "uniprot_id": "A0A8M6YX66_DANRE", "id": "A0A8M6YX66-1", "name": "", "aln": "---MDLTEEDLSARVLLRKVLHTEQPRSPVTRSANSVRRSARMKNAAGLESPGSALRHRLKKKLHESAAASPLPLPKRMRSSVVKQNPPNMAPSTLDDEDLTTRGLLRGIIHMETETSLLMSGQPALQESEPNPETSVSSAGERTEGLSGAELSDLTLHTEPLTHVVRGLSRKKQQHVFSVSALEKQFDQLTDNTEDVSRVSERGDVFQEKPDTSQDSDFSAGSKSLCSVSGLNLTLKTPFVERRSERAVLQRKVSNRRLQSVEAFDEAVQRCLEQGPNQEQSVSLAGKTLDDSSWQKFTLGLNDVTELYVQMKKDDTVEPSAEIDNDEQAETEKDEQYHVSEIPNDRDSKILIQDEKEHEMESLLLDDEEVVPSSQESPRDEVFLNTEYDIILAPTQAMTESLPQSQNAELEGQLSGENDVVVEEIAHEEIVEDVEHENVVEIEAEEVEYAEENSDGLNYPERITRRAHGSEGAGAVLAIPGTSTRVTKSFGAGLNPREKDLLDLIDGDRESVENILDEERQALVSPMSPQFHHEEVIITSEQRSTQNEASLNEDDLPQVTENEDVNQSEEKREELIDSEPANQPPEPAEELIESQSANQSTEADEEKELIDSEPTNQSTKPEDDEEEEELMDSESTNQSTKPDDDEDEEELMDSEPTNQSTKPDDDEEELIDSEPTNQSTEPPQDGEDMMESELANQSLQPAEDKEEMLESEPANLTSEAAVEEEDIIDSEPANQSYEFAQEEEEEEDVDEDDARSAELSIKTPAFVKQKRVFASPSAQTTLTVLKEVNAGAGPQVSRRAPRQKRQTGTDVLPKSYVMSIFKHFAKTKVASDVYPVINEILKKYFDRLADDLETYATHAKRKTIEVEDFELLMRRQGFVTDSMPVNVLIEKYLPLEYRKLLIPVATSGNKVIPTQRR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: * : *.***:**.* :.::* : ::. . .. : : : * : :.. * : :: *: *.* **:.*: .*:* :*. .: :. *:. .* : * .*.:* : . : **:: : :*.::: .:* .*: :. . . .:**:: . . :*. * *: . *: . *: . :. : .:. :: : **.:::.: . .. : *: * *. .. . . .: * * .*: : :. ... *: .: : :.. : * . .* * :.** : ::. : : .. * :.:*.. :* : . :::: *.:**::*.:***.:*:** ** :: :*: *******:***.:. :**:*::******: *** * **.*:*:* ", "identical_positions": 95, "similar_positions": 173, "identity": "10.34%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3264", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTV0-1", "uniprot_id": "D3ZTV0_RAT", "id": "D3ZTV0-1", "name": "", "aln": "MLSSGDFTSASWELVVRVDHANEEQQTDITLRVSGDLHIGGVMLKLVEQMNIAQDWSDFALWWEQKRCWLLKTHWTLDKCGVQADAKLLFTPQHKMLRLRLPNTRTVRLRVSFSAVVFKAVADICKVLNIRRPEELSLLKPSGDYCKKK-----------------------KKKEKNSKEPVIEDILNLESSSTSSGSPVSPG-LYSKTMTPTYDPINGTPALST--------------MTWFGDSPLTEQNCSVLAFSQPPPSPEVLAEMFQPRSLVDKAKMNAGWLDSSRSLMEQSIQEDEQLLLRFKYYTFFDLNPKYDAVRINQLYEQARWAVLLEEIDCTEEEMLIFAALQYHISKLS--------LCAEIQDFATKSE-VDEVEAALSSLEVTLEGGKADNTLEDITDIPKLADYLKLFKPKKLMLKAFKQYWFVFKDTSIAYFKNQE-LEQGEPIEKLNIRGCEIVPDVNVAGRKFGIKLLIP--VADGMN-EVYLRCDHEDQYARWMAACILASKGKTMADSSYQPEVVSILSFLKMKNRNSSP-LVASSLESMDMNPECLVSPRCAKKHKSKQLAARILEAHHNVAQMPLVEAKLQFIQAWQSLPEFGLTYYLVRFKGSKKDDILGVSYNRLIRMDAVTGIPVTTWRFANMKQWNVNWEIRQVAIEFDQNVSIAFTCLSAGCKIVHEYIGGYIFLSTRSKDQNETLDEDLFHKLTGGQD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59113-1", "uniprot_id": "FERM1_MOUSE", "id": "P59113-1", "name": "Fermitin family homolog 1", "aln": "MLSSGDLTSASWELVVRVDHANGEQQTEITLRVSGDLHIGGVMLKLVEQMNIAQDWSDYALWWEQKRCWLLKTHWTLDKCGVQADANLLFTPQHKMLRLRLPNAKTVRLRVSFSAVVFKAVADICKVLNIRRPEELSLLKPSSDYCKKK-----------------------KKKEKNSKEPVIEDILNLESSSTSSGSPVSPG-LYSKTMTPTYDPINGTPALST--------------MTWFGDSPLTEQNCSVLAFSQPPPSPDVLADMFQPRSLVDKAKMNAGWLDSSRSLMEQSIQEDEQLQLRFKYYTFFDLNPKYDAVRINQLYEQARWAVLLEEIDCTEEEMLIFAALQYHISKLS--------QCAEIQDFATKSE-VDEVEAALSSLEVTLEGGKADNTLEDITDIPKLADYLKLFRPKKLMLKACKQYWFVFKDTSIAYFKNKE-LEQGEPIEKLNLRGCEIVPDVNVSGRKFGIKLLIP--VADGMN-EVYLRCDHEDQYARWMAACILASKGKTMADSSYQPEVISILSFLKMKNRNSSP-LVASSLENMDMNPECLVSPCCAKKHKSKQLAARILEAHHNVAQMPLVEAKLQFIQAWQSLPEFGLTYYLVRFKGSKKDDILGVAYNRLIRIDAVTGIPVTTWRFANMKQWNVNWEIRQVAIEFDQNVSIAFTCLSADCKIVHEYIGGYIFLSTRSKDQNETLDEDLFHKLTGGQD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQL6-1", "uniprot_id": "FERM1_HUMAN", "id": "Q9BQL6-1", "name": "Fermitin family homolog 1", "aln": "MLSSTDFTFASWELVVRVDHPNEEQQKDVTLRVSGDLHVGGVMLKLVEQINISQDWSDFALWWEQKHCWLLKTHWTLDKYGVQADAKLLFTPQHKMLRLRLPNLKMVRLRVSFSAVVFKAVSDICKILNIRRSEELSLLKPSGDYFKKK-----------------------KKKDKNNKEPIIEDILNLESSPTASGSSVSPG-LYSKTMTPIYDPINGTPASST--------------MTWFSDSPLTEQNCSILAFSQPPQSPEALADMYQPRSLVDKAKLNAGWLDSSRSLMEQGIQEDEQLLLRFKYYSFFDLNPKYDAVRINQLYEQARWAILLEEIDCTEEEMLIFAALQYHISKLS--------LSAETQDFAGESE-VDEIEAALSNLEVTLEGGKADSLLEDITDIPKLADNLKLFRPKKLLPKAFKQYWFIFKDTSIAYFKNKE-LEQGEPLEKLNLRGCEVVPDVNVAGRKFGIKLLIP--VADGMN-EMYLRCDHENQYAQWMAACMLASKGKTMADSSYQPEVLNILSFLRMKNRNSAS-QVASSLENMDMNPECFVSPRCAKRHKSKQLAARILEAHQNVAQMPLVEAKLRFIQAWQSLPEFGLTYYLVRFKGSKKDDILGVSYNRLIKIDAATGIPVTTWRFTNIKQWNVNWETRQVVIEFDQNVFTAFTCLSADCKIVHEYIGGYIFLSTRSKDQNETLDEDLFHKLTGGQD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QBZ4-1", "uniprot_id": "E9QBZ4_DANRE", "id": "E9QBZ4-1", "name": "", "aln": "MASAGEHG-HTWELSIQVDQREGDEGMRFKLRVKGDLHVGGLMLKLVEKIKAPQDWSDHAIWWEQKSCWLLKTHWTLDKYGIQANADLRYTPQHKSLCIQLPNMKNIKLPVTFSGVVFRAVAEICKTLNIRRTEELSLLKPT-DEPKKK-----------------------KKKDK-GTDLATDEILTMDITGGALG-------MYSKTMTPIYDPDSGSPVSST--------------SLWYGGSPLTAC--------QPNLPPEELAKLYKPLTMEDKAAINAGWLDSSRSLMEQGIQENDRLLLRFKYHCFFDLNPKYDAVRITQLYEQARWAILLEEIDCTEEEMLMFASLQYHICKLT--------LSTEPLDNSDEKE-VDEVEAALSNLETHLEGRNADKILEDITDIPKLEDTLKLFRPKRLTLKPYKEYWFVFRDTTISYFKNKD-SANKEPIEQLHLRGCEVIPDVNVTERKFGLKLLLP--AADGMN-EVYIRCENETQYAKWKAACILASKGKTMAYSSYRTEVKNIQSFLQMKSLAPPPGQAAPDVESMEMNPECFVSPRYAKKFKTKQLTTRILEAHHNISQLSLMEAKMRFIQAWQSLPDFGIKYYIVRFRGSKKDELLGISYNRLIRIDMSTGLPVTTWRFSNMKQWNVNWEIRQVTIEFDQSVSIAFSCQSCDCKVVHEYIGGYIFLSTRSKDQNETLDEELFHKLTGGQD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZI3-1", "uniprot_id": "UN112_DROME", "id": "Q9VZI3-1", "name": "Unc-112-related protein", "aln": "MIHVGENT---WNLRILIT----DLQVEKTLRVKGDQHIGGVMLNLVDPE-LPKDWSDHALWWPAKNIWLTRTRSTLDQAGVQSDSFLHFTPMHKTLRVQMPDLRYLDYRVNFSAKTFGAVVSLCKDLDIRYPEELSFCKPLEPEHLKKNFSKLPQRK-IPVAEANGIAYVQPALDTNSFVPITGAYNG---SNGSLDR-SHNGNLLCAPASPYTRRAATAPGTPISSPTGTWKHNSTGYASYDSNSS-FGDLQENLAMSPRSPSPDVRARLVRPKSRVEKARLNVGWLDSSLSIMEQGVREYDTLCLRFKYFTFFDLNPKYDQVRINQLYEQAKWSILNEELEPTEEETLMFAALQFQVNHQTDLHPPG--IDSGIDTSSQETGGEDDIDSALNELQITLEGPGGGKDQGNITRIPELSDYLKFLKPQRFTLKGYKRYFFTYRDLHLHLYKSQDESRRGAPTISINLKGCEVTPDVNLAQGKFAIRLEVPSEIRNGPNSEVWVRCDNEEQYAKWMAACRLAAKGRSLADSSYDSEVSSIRSLLQMQK---PAQGAPLTVNPRSVEPMDYLSPKMMRKLSSK-AVQRILEAHANVRQLSLMDAKMKYIQAWQSLPDFGVTLFIIKFDGHKKEELLGVANNRIMRMDLNTGDHIKTWRYNTMKAWNVNWGIKCMMIQLQD-ENIVFSVQSADCKVVHEFIGGYIFMSMRSKENNQTLNEEMFHKLTGGWS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VVD2-1", "uniprot_id": "Q9VVD2_DROME", "id": "Q9VVD2-1", "name": "", "aln": "MIHVGENS---WNLRIFIT----DLALEKTMRVRGDQHIGGIMLQLVDPE-NPKDWSDHALWWPARNVWLSRTKLTLDQCGVQADSLLHFTPMHKILRVQLPDLRYLDSRVDYSVKTFSAVVNLCKQLDIRYPEELSLCKPLEAEHLKRNFAQVPHQKRVPIAEPDGTTYLQPAADTNSFVPISTSFHGEGGSTGSLDKPSAPGSFFCAPLSPHNHRAR-SPVRTVSPFPGTWKQSQLGYATYDSSSSSLGDFQENLASSPPTPCADVRALQLRPKSLVEKARLNVGWLDSSLSIMEQGIREYDTLCLRFKYFTFFDLNPKCDQVRINQLYEQAKWSVLNEELDCTEEESLMFAALQFQVNHHVDHTPQGAAVDSGIETSSQENDNEDEIDSALKELQITLEGPDYGGDSRNITRIPELSDYLRYLKPQRFTLRGYKRYYFTYRDLHLHLFKNAEDSRRVAPAISINLKGCEVTPDVNLSQGKYAIRLEVSPDGGHGINSEVWVRCENEQQYAKWMAACRLAAKGRSLADSSYESEVDSILSLLQMQR---PAHGVHVNIDPRSVEAVDYLSPKIIRKLSNK-AVQRILEAHANVRELNALDSKLKYIQAWRSLPDFGVSLFIIKFDGHRKEELLGVAHNRIMRMDLSSGDHIKTWRYNTMKAWNVNWNIKCMMIQFED-ENVVFSCHSADCKVVHEFIGGYIFMSMRSKDTNQTLNEELFHKLTGGWS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : *:* : : : .:** ** *:**:**:**: .:****.*:** : ** :*: ***: *:*::: * :** ** * :::*: : : * :* .* ** .:** *:** .****: ** *: :. . : : . : . . :* :* . : ..*. .: * :* : :** :*.****** *:***.::* : * *****. ******* * ***.******:*::* **:: **** *:**:**::: : : : :. *::::**..*: *** . :** **:* * *: ::*::: : *.*:* ::* : :*. : . * .::::***: ****:: *:.::* :. .* * *:::**::* ***:* *** **:**:::* *** .** .* *:*:*: .. . :: .::. :** :: ..* . ****** *: :: :::*:::****:***:**:. ::::* * :*:::**:: **::::* :* :.***: .:* ***** : : *:::: .*: *..**:***:******:* ***: *:**:*::******* .", "identical_positions": 232, "similar_positions": 206, "identity": "31.82%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3272", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1B0GTU1-1", "uniprot_id": "ZC11B_HUMAN", "id": "A0A1B0GTU1-1", "name": "Zinc finger CCCH domain-containing protein 11B", "aln": "MPNQGEDCYFFFYSTCTKGDSCPFRHCEAALGNETVCTLWQEGRCFRRVCRFRHMEIDKKRSEIPCYWENQPTGCQKLNCVFHHNRGRYVDGLFLPPSKSVLPTVPESPEEEVKASQLSVQQNKLSVQSNTSPQLRSVMKVESSENVPSPKHPPVVINAADDDEDDDDQFSEEGDETKTPTLQPTPEVHNGLRVTSVRKPAVNIKQGECLHFGIKTLEEIKSKKMKEKSEEQGEGSSGVSSLLLHPEPVPGPEKENVRTVVRTVTLSTKQGEEPLVRLGLTETLGKRKFS--TGGDSDPPLKRSLAQRLGKKVEAPETNTDETPKKAQVSKSLKERLGMSADPNNEDATDKVNKVGEIHVKTLEEMLLERASQKHGESQTKLKTEGPSKTDDSTS--GARSSSTIRIKTFSEVLAEEEHRQQEAERQKSKKDTTCIKLKTDSEIKKTVVLPPIVASKGQSEEPAGKTKSMQEVHMKTVEEIKLEKALRVQ-----QSSESSTSSPSQHEATPGARLLLRITKR--TWRKEEKK--LQEGNEVDFLSRVRMEATEASVETTGVDITKIQVKRCEIMRETRMQKQQER-----EKSVLTPLQGDVASCNTQVAEKPVLTAVPGITWHLTKQLPTKSSQKVEVETSG--IADSLLNVKWSAQTLE-KRGEAKPTVNVKQSVVKVVSSPKLAPKRKAVEMHPAVTAAVKP----LSSSSVLQEPPAKKAAVDAVVLLDSEDKSVTVPEAENPRDSLVLPPTQSSSDSSPPEVS--GPSSSQMSMKTRRLSSASTGKPPLS---VEDDFEKLTWEISGGKLEAEIDLDPGKDEDDLPLEL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O75152-1", "uniprot_id": "ZC11A_HUMAN", "id": "O75152-1", "name": "Zinc finger CCCH domain-containing protein 11A", "aln": "MPNQGEDCYFFFYSTCTKGDSCPFRHCEAAIGNETVCTLWQEGRCFRQVCRFRHMEIDKKRSEIPCYWENQPTGCQKLNCAFHHNRGRYVDGLFLPPSKTVLPTVPESPEEEVKASQLSVQQNKLSVQSNPSPQLRSVMKVESSENVPSPTHPPVVINAADDDEDDDDQFSEEGDETKTPTLQPTPEVHNGLRVTSVRKPAVNIKQGECLNFGIKTLEEIKSKKMKEKSKKQGEGSSGVSSLLLHPEPVPGPEKENVRTVVRTVTLSTKQGEEPLVRLSLTERLGKRKFS--AGGDSDPPLKRSLAQRLGKKVEAPETNIDKTPKKAQVSKSLKERLGMSADPDNEDATDKVNKVGEIHVKTLEEILLERASQKRGELQTKLKTEGPSKTDDSTS--GARSSSTIRIKTFSEVLAEKKHRQQEAERQKSKKDTTCIKLKIDSEIKKTVVLPPIVASRGQSEEPAGKTKSMQEVHIKTLEEIKLEKALRVQ-----QSSESSTSSPSQHEATPGARRLLRITKR--TGMKEEKN--LQEGNEVDSQSSIRTEAKEASGETTGVDITKIQVKRCETMREKHMQKQQER-----EKSVLTPLRGDVASCNTQVAEKPVLTAVPGITRHLTKRLPTKSSQKVEVETSG--IGDSLLNVKCAAQTLE-KRGKAKPKVNVKPSVVKVVSSPKLAPKRKAVEMHAAVIAAVKP----LSSSSVLQEPPAKKAAV-AVVPLVSEDKSVTVPEAENPRDSLVLPPTQSSSDSSPPEVS--GPSSSQMSMKTRRLSSASTGKPPLS---VEDDFEKLIWEISGGKLEAEIDLDPGKDEDDLLLELSEMIDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NZF1-1", "uniprot_id": "ZC11A_MOUSE", "id": "Q6NZF1-1", "name": "Zinc finger CCCH domain-containing protein 11A", "aln": "MPNQGEDCYFYFYSTCAKGDSCPFRHCEAALGNETVCTLWQEGRCFRQVCRFRHMEIDKKRSEIPCYWENQPVGCQKLNCAFHHTRSRYVDGLFLPPSKTVLPTVPESQEEEVKTSQLTVQQSKLSVQSNPSPQLRSVMKVESSENVPSPTHPPVVINAADDDEDDDDQFSEEGDESKTPALQPSPDVHNGLRVASARKPGVSLKQGECLNFGIKTLEEIKSKKMKEKSKKQGEGSSGVSSVLQQPQPNPGPEKENVRTVVRMVTLSSKP-EEPLVRLSLSERLGKRKLS--VGGDSDPPLKRSLAQRLGKKVESPETNIDKAPKK-----------------------ERGHKAGEIHVKTLEEILLERASQKRGELQTKLKAEEPSGADDSPS--GTKSSSSVRIKTFSEVLAEKKHRQQEMERQKSKKDTSCLTLTDDTEMKKTVSLPTVAVSKGQPEEPAGRARSMQEVHIKTLEEIKLEKALRVQ-----QSSESSGNSRPQAEAAPGTKRLLRITKR--AGVKEEKKCGLEDSGDPPQSSVTKMEANETSDETIS-DPTKLAVNRCDTVKEKHTQRLQERGASQKEKAALSSVRGDEASSYTRVAGKPVLTAVSGVTRHLAKRLPVESSQKGEVETSG--IGDSILNVKCAAQTLE-KRSKVKPKVNVKPSVVKVVSAPKLAPKRKAVEMHSAVIAAVKP----LSSSSVLQESPTKKAAV-AVVPLLSEDKPVTMSETENPKDSSVLSSAQAASEPLLPEGS--GPSSSQTATKPRRLSSASTGKPPLS---VEDDFEKLIWEISGGKLEAEIDLDPGKDEDDLLLELSEMIDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2BGM4-1", "uniprot_id": "A0A8M2BGM4_DANRE", "id": "A0A8M2BGM4-1", "name": "", "aln": "MTLQGDDCYFFYYSTCTKGDSCPFRHCEAAMGSETVCNLWQEQRCFRNVCKFRHMEIDKNRKEIACYWENQPAGCQKPHCAFHHEKPRIINGNYLAPDKGQVARK----DNEEAPLEEKVNQVPAPSANPTNPQLRGVKRTETQENVPSPTHPPVVINPVDDD-DEDDQFSEEGDES-----------------LGVSPRKLVSSKHDSLDFGIQTLEEIRLRKALMSNLKKAR-QSTVQGLAQISRPTVEKENIQSLSRLEVNNVKIDSSGKEVGKRRIADRLGKRILERDVPGEEGPPLKRSLAERLGGVVESSTDVLTKKSHKPVHER-------LGLTTDMSSGDSEPKSSGDIRIKTLEEIRQEKAAKNLSKSKVVRVVKEVPQKEISPSRKSVKPVAGPQVKTFSEILHEKKRKMQEKKEQ---------------EINKADKSPERSEEPSSARAANKTTVTTGEVRVKTLEEIRREKAARMQTQLGETTDNKTPTSSEAELSGPSKRRILRINKTSPAAVTQTKPDASEKKPEPATEANGKIEPSSEVVKVKTFEEIMREKKLRKLQEEQVTSSNQTDVGASASPPAPEPSVQPQTTVRQRITFKAKPSPPVSDAVVIEKSSPERSEDSTPSTNTPKPSTSPVRPVRIAEGIVTPAETKVRPKVNVKPSVVKPAAPS--VQKRKAAKVHSAVAEVKPLNTTCQTPSSPVMPNKRLKMASPTSKKVVQSDTQQVPSNIENIQMMPVSCSEPASTTSVETVVVPHSPVIKTPSMQRSRRCSTTSGRPPVVTSSSMDDFEDLLDEFTDDRLEDELELDSGKGEDDLLLELSEMIDS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 240, "similar_positions": 254, "identity": "28.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3273", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O75475-1", "uniprot_id": "PSIP1_HUMAN", "id": "O75475-1", "name": "PC4 and SFRS1-interacting protein", "aln": "-----------MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYSENKEKYG--KPNKRKGFNEGLWEIDNNPKVKFSSQQ---------------AATKQSNASSDVEVEEK--------ETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPK-----------------------PRGRPKMVKQPCPS-----------------------------------------------------------------------------------------------------------------ESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESK-----------------------------------------------RKNLAKTG---------------------------------------------------------------------------------------------------VTSTSDSEEEGDDQEGEKK---------------------------RKGGRNFQTAHRRNMLKGQHEKEAA------------------------DRKRKQEEQMETEQQNKDEGKKPEVKKVEKKRETSMDSRLQRIHAEIKNSLKIDN-----------LDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKFKNMFLVGEGDSVITQVLN-------KSLAEQRQHEEANKTKDQGKKGPNKKLEKEQTGS-KTLNGGSDAQDGNQPQHNGESNEDSKDNHEASTKKKPSSEERETEISLKDSTLDN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99JF8-1", "uniprot_id": "PSIP1_MOUSE", "id": "Q99JF8-1", "name": "PC4 and SFRS1-interacting protein", "aln": "-----------MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYSENKEKYG--KPNKRKGFNEGLWEIDNNPKVKFSSQQ---------------ASTKQSNASSDVEVEEK--------ETNVSKEDTDQEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVDTEEAGMVTAATAS-NVKASPKRGRPAATEVKIPK-----------------------PRGRPKVVKQPCPS-----------------------------------------------------------------------------------------------------------------DGDMVIDEDKSKKKGPEEKQPKKQLKKEEEGQKEEEKPRKEPDKKEGKKEVESK-----------------------------------------------RKNLAKPG---------------------------------------------------------------------------------------------------VTSTSDSEDE-DDQEGEKK---------------------------RKGGRNFQAAHRRNMLKGQHEKEAG------------------------DRKRKQEEQMETEQQNKDEGKKPEVKKVEKKRETSMDSRLQRIHAEIKNSLKIDN-----------LDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKFKNMFLVGEGDSVITQVLN-------KSLAEQRQHEEANKTKDQGKKGPNKKLEKEPTGT-KSLNGGSDAQESNHPQHNGDSNEDGKDSREASSKTKPPGEEREAEISLKESTLDN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PX56-1", "uniprot_id": "A0A8M9PX56_DANRE", "id": "A0A8M9PX56-1", "name": "", "aln": "MQKGVKMKSDQTTDDFTPGDVVFAKMKGYPFWPARIAEG-----KAPKNKIPIFFYGTHSTTFLFPKDIVHYWPNKQKYA--QANKRGGFEEGMWEIENDPGVGLRGQKKAALVKRLSESRLKWKNKKKKKAENQTEVKKPPKSAKDPVSNSDSKAATPHKRETKSESVTLKDDKNTETRPTRSRDSSAKTSTDKRRTDKVVPARKMTSVKTITTGWRRLPSSVILARRMDAAKTLSAHRKHVLNRKIISTAKKRIDAVNHRKPSRITRSTADPIEATDDVTAKPLALKRKRKQNDSEVKGDAPISIPATDISASSTPTGSKRRRLTEPEKKSKDDEKELKENEAQSKEKNEVEQKIEKQNEVEKSNADKNKMMEKKNQAEKIVAENETENKGAKKKESEKSDAEKEKSEKKETKKIETERKEARNSEAESKEPCKNDSEKKEAERIETRKSESEVLVAKNKESEKRETRKSESEMKEARKNESKKQEARKSESEKRETRKSESEMKEARKNESEMKEARKSESEKRETRKSESEMIEARKNESEMKEARKSESERRETKNSEAEIKEARKNESEIEAIRSNSEKRETRKSDSEMEAKNNESEKREAGKSESEMKEARKNESEKKEARKRETRKSESDMKEAKRKETRKSESEIKVAKDNDSEKRETTKNESEIEAKNKESEKREAGKSESEIKEARKNESEKEEARKRETRKSESDMKEARKNESEIKVAKDNDSEKRETRQNEFEIETKNNESEKRETRKSESEMKEARKTDSEIIEAKKNESEKESKRDESEKRETRKNESEMKEARKNESEKRAIRNESEKRETKSQSEIKESEKREARNIESEKKEAKKIDSEMKQARKNESEKKEARKSESEKKEAERVETRKTESEKKEVRKSESEKKEAERKLERKSESERKEAKKSESENKEARGNESEKKGARRSESEKKEARQSESEKKEARRSESEKRENRRSESEKKEARRNESEKRETRSESEKRETRRNESEKREPRWRESEKKETRRRESEKKETRRSESEKKEPRSESKKKEARRSESEKKEARRSEFEKKEARRSEFEKKEARMSESDKKEAKRNESEKKEARRSEFEKKEARRSEFEKKEARMSESEKARRSEFEKKEARRNESEKKDARRNESEKKEARRNESEKKEARSESEKKEARRNESEKNEGRRNESEKKEERRIESEKKEARKNKSEKEARRSDSELKEARRKESELKEARRNESVKSDAEKDAVEKNKAEKNKLPEKRKEINVEERRETMTKPKQTKSCAPVSSDETQEEKKPRDEERCKILAEKRQSVLKSLQGLVTSTRGKTPSGSEQTTETKEPRKERNHRLKQPAEDEKKDTEKRKEQEKRNTEQQISSSKEEERRAHSLSVTDSLLYRLHGDIRISMTLENPDVSKCLSALDELSNVPVSSRNIQNHSELIDTLRKMRWFRGSEAIMFKASMLYHRFKNIYLIGDADETLSQEYINSLQQEREREIEERHRDAVRTEADVRKTPDFTSCF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAA9-1", "uniprot_id": "Q9VAA9_DROME", "id": "Q9VAA9-1", "name": "", "aln": "------MGKEKAAASYSIGDLVFAKVKGYPPWPAKITKS------NNNKKYNVYFYGTGETANIKLEDLFPYASNKERFATEKIMKRAKFIEAIDQIESALRGED--------------------SAPIDLLDGAEPVAPP--------TTGDGVKTEEPKPEPGPEPATAAPVAAAAEKPKKSGTRKTKAPPRHVDGDSEAGAELAPPPAKRRVPTEGLATAAAIPA-----------------------APAAATPTSS---------------------------------------------------------------------------------------------------------------------------KKSVKKSKPTAAVTPIQKRSRPVNNIRNEMLMVYMPTAKCLGIVINYK-------------------------------------------------------------------------------------------------------------------------------------------------------------KPESFESAAAEEAWMEN-------------------------ARKEALELKLKLESGQINPES------------------------------MPDRIVVEPTRSEIPKQEALRFIEELIEHEDALFMERDFIQLSQQLRECLGLRR-----------ANVGKCLEILEQFKEVEFTKLMLLRNPECVDIMRRLRRYVGN------------------------------------------LELWKMDLSDEVEFKERAQTIRKVSSGIYDGFKSLFNPEPESEDNFWIDFCEKVKIYKTYTKNINENLRVGMNERGYNSLVLAKEAAASAGSAPQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:. **::***:**** ***:: : .:* ::*:** .*: : :*:. * **:::. : ** * *.: :*:. . .. * .. . : :. * .* : . :. .:: . . * . .: . :. . .. :. .:.* . :. . :. ::* : : * ..:* . :*. . ** ::: . : : : .: *:*. : . * . : ::: . :. . . : . : : . : :: . . * : : : : : . :*:.. *. . ..: . : : * : . :.. .* . ", "identical_positions": 45, "similar_positions": 139, "identity": "2.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3286", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A8G9-1", "uniprot_id": "ZFY26_RAT", "id": "D4A8G9-1", "name": "Zinc finger FYVE domain-containing protein 26", "aln": "MSYPFGKEETTTEKQLFEFFCECLRRGDWELAQACVPQLQ-RGQGEIPQKVEDILQALVQCPILLRCGPDINPQRLAWLWLLVLEKWLPPEKKLLSTVFRRKLEFLFLSEDLQGGIPETILKELFETLAQGPAGCTSDRSQRWESGAPQLSPEAVSMLWNLLK-QAPGPAQALLELLLEERHSASLCHSSLQKSLLDLIRKALQTLRDPASQPAGVTDAVCGALQALCCTAELPEGEWHVLCEELLETCRTEGSPLKEERLLGCLLHKAGRSLLSLYGHTYAEKVAERPPKASLSGK---DHPDPERAMLALFSTPDPAHAWKMAFFYCLSNNKHFLEQILVTALTLLKEEDFPSLGYLLDREFRPLSHLLVLLGWTHCQSLESAKRLLQTLYRNQDQGHDELLRDACEGLWAHLEVLEWCVQQSSSLIPKRELLCHLHGGDSHSVLYSLHHLTNLPALREEEVLKLLQKVPTKDLQGEHDTHDASVPEHLSQCQSLTLYQGFCAMKYAVYALCVNS--HQHSQCPDCRDSASSEELALVEPGRDSLPSPGASHLFPTYLARCRQYLQRIPDSLCLEILENIFSLLLITSADLHPEPHLPEDYAEDDDIEGKGPWGLWSPSESPQHIAATERRSERASMG-PRDLAPTGPGCPKGEPKDNSPGPHTHSFLDLKHFTSSLSGFLADEFAIGAFLSLIQEQLNELS------SHRTPEETELLEDQSCWAARDGLQGRLHRFSKVLSEAQWRYKVVTSNQSSEEQPSRRYRPTAKRHSSLRR------GRRTRRTRADGRERGS-NPSLEGTSSELSTSTSEGSLSAVSGQVEADNRFQPQPQSSIIPMMFSPPESLLASCILRGNFAEAHQVVLMFNLKSSPSAGELMFVERYQEVIQELARVEHKIENQ------NSDGGNNTVRRTGSGRS--------TLQAIGSAAAAGMVFYSISDVTDKLLSPSEDPIPTLQEDFWINAALTETNTPLRGVLEDLSPPAMAAFDLACCQCQLWKTCKQLLETAERRLSSSLEGRGRRLDQVVLNPDGMRGFPFVLQQISKILSYPLTVTGLTKSET-LEERGGGAPR-CSISELLQMCWPSLTEDCIASHTSLSQQLDQALQSLREALTLSEP---KSTPLTCLVEQAAQKAPEAEAHPVHIQSQLLQKTLGKQTLAGPR----QTDYVGAFFSYCSSLAKVLLRSLSSDPDNVEVKVGNPFVLLQQSSSQLVSHLLLERQVPPDRLAALLAQEHLNLSVPQVIVSCCCEPLTLCLSRQSQQASSLTAHLG------MLAQGHASHLLDGLPLSVLGSPRPSENPSAER------------------KSDSSPKDS-LPAFTASALAFLKSRSKILAMVACLRASRGTKVSRPSLSWKELR------GRREAPLTAEKVAQECEHLLEQFPVFEAALLANWEPLQ-QASESRPSLAASLCGQARLSTVLLGLHSTLAQDVVTEAFEEALVARDWPRALQLIDVYGQDSDDLSSVRDSVLTCATVCDKEGWQYLFPVKDASLRSQLALRFVDKWPLESCLEILAYCVSDMAVPEELKSELQRKLTELRVYQKILGLQDPPVWCDWQTLRSCCAEDPSTVMDMMLGSQEYELCEEWGCLYPIP-----REHLVSLHHKHLLYLLERREYEKALQLLQRIPDPTMCLEVTERSLDQHPSLATSHFLANYLTSHFYGELTTDRHHEIQALYMGSKVLLTLPEQHRASYAHLSSSPLLMLEQLLMNMKVDWATTAVQTLQQLLAGQDIG-------------FTLDEVDSLLSRYAGKALDLPYPLREK-RSDSMIHLQEPVHQASDPETLSRSSSAEFSAAAAAPAPAAPGSALVCSPSPKERAFPQTQPPLE--FVPPETPPARDQWVPDETESMCMVCCREHFTMFNRRHHCRRCGRLVCGSCSTKKMVVEG-CRENPTRVCDQCYSYYNKDAPEESPCQSEVPDSAKNESPSYSAVVRIPKATEVEWILSLNEEENELVRSEFYYEQAPSASLCIAILNLHRDSIACGHQLIEHCCRLSRGLT-NPEVDAGLLIDIMKQLLFSAKMMFVKAGQSQDLALCDSYISKVDVLHILVAAAYRHMPSLDQILQPASVTRLRNQLLEAEYYQLGVEVSTKTGLDSTGAWHAWGMACLKAGNLTAAREKFSRCLKPP-----------------------LDLNQLSHGSRLVQDVVEYLEST----------------------------------VRP-LVSLQDDDYFATLRELEATLRTQSLFLEAIPDGKIMNNTYYQECLFYLHNYSTNLAIISFYMRHNCLREALLHLLNKESPAEVFIEGIFQPSYKSGKLHTLENLLESID-PTLESWGAYLIAACQHLQKKNYYHILYELQQFMKDQVRAAMTCIRFFSHKAKSYTELGEKLSWLLKAKDHLK--------------IYLQENSRSSGRKKTTFFRKKMAAADVSRHMNTLQLQMEVTRFLHRCES---------------ARTSQITTLPLPTLFGNNHMKMEVACQVMLGGKNVEDGFGIAFRVLQDFQLDAAVTYCRAARQLVEKEKYGEIRQLLKCVS-ESGMAAKSDGDTILLNCLEAFKR--IPP--QELEGLIQAIHSDDNKVRAYLTCCKLRSAYLIAVKQEHTQAAALVQQVQQAAKSSGDSVVQDICAQWLLTSHSRGAHGSGSRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5DU37-1", "uniprot_id": "ZFY26_MOUSE", "id": "Q5DU37-1", "name": "Zinc finger FYVE domain-containing protein 26", "aln": "MSYPFGKEETATEEELFEFFCECLRRGDWELAQACVPQLH-RGQGEIPQKVEDILQALVQCPILLRCGPDINPQRLAWLWLLVLEKWLAPEKKLLSTAIRRKLEFLFLSEDLQGDIPETILKELFETLAQGPAGSIPDRR------TPQLSPEAVSVLWNLLK-QAPRPAQALLELLLEDHHSASLCPSPLQKSLLDLIREALQTLRDPASQPPGVADAVCGALQALCCKAELPESEWRVLCEELLETCRTEDSPLQEERLLGCLLHKAGRNLLSLYGHTYAEKVAERPPKATLSGK---DHPDPERAMLALFSTPDPAHAWKMAFFYCLSNNKHFLEQILVTALTLLKEEDFPSLGYLLDREFRPLSHLLVLLGWTHCQSLESAKRLLQTLYRTQDQGHDELLRDACEGLWAHLEVLEWCVQQSSNLIPKRELLCHLHGGDSHSVLYSLHHLTNLPALNEEEVLKLLQKEPTKDLQGEHETHDASVPEHLSQCQSLTLYQGFCAMKYAVYALCVNS--HQHSQCQDCRDSAS-EDLALVEPGSDSLPSPGASHLFPTYLARCRQYLHSIPASLCLEILENIFSLLLITSADLHPEPHLPEDYAEDEDIEGKGPLGLRSPSESPQHIAATERRSERASMG-PRNPAHTVPGCPKAEPKDSSPGPHKHSFLDLKHFTSGVNGFLADEFAMGAFLSLLQEQLTEIS------SHRTPEETKLPEDQSCSAARDGLQSRLHRFSKVLSEAQWRYKVVTSNQGSEEQPSRRYRPIATRHSSLRR------GRRTRRTRADGRERGS-NPSLEGTSSELSTSTSEGSLSAVSGQVESDSRFQTQPQSSIIPMMFSTPESLLASCILRGNFAEAHQVVLMFNLKSSPIAGELMFVERYQEVIQELARVEHKIENQ------NSDGGNNTIRRTGSGRS--------TLQAIGSAAAAGMVFYSISDVTEKLLSPSEDPIPTLQEDFWINATPMETTTPLREVLEDLSPPAMAAFDLACCQCQLWKTCKQLLETAERRLSSSLESRGRRLDQVVLNPDGMRGFPFVLQQISKILSYPLMQTGLAKSET-LEERGGGAPR-SSISELLQMCWPSLTEDCVASHTSLSQQLEQALQSLREALALPES---KSTPLSCLVEQAAQKAPEAEAHPVHIQSQLLQKTLGRQTPAGHR----QTDYVGAFFSYCSSLAAVLLRSLSSDPDHVEVRVGNPFVLLQQSSSQLVSHLLLERQVPPDRLAALLAQEHLNLSVPQVIVSCCCEPLTLCLSRQSQQASSLLTHLG------MLAREHASHLLDGLPLSTLGSPRPSENPSAER------------------KSHSSPKDS-LPAFTASALAFLKSRSKILAMVACLRTSRGTKVSKPGLSWKELR------GRREAPLTAEKVAQECEHLLEQFPVFEAALLANWEPLQ-QASEPKQSLAASLCGQANLSTVLLGLHSSLALDILTEAFEGALVARDWPRALQLIDVYGQDLDDLSIVQDSVLTCAAVCDKEGWQYLFPVKDASLRSQLALRFVDKWPLESCLEILAYCVSDMAVQEELKSELQRKLMELRVYQKILGLQDPPVWCDWQTLRSCCAEDPSAVMDMMLDSQEYELCEEWGRLYPIP-----REHLVSLHHKHLLHLLERSEHDKALQLLQRIPDPTMCLEVTERSLDQHPSLATSHFLANYLTSHFYGELTTDRHREIQALYMGSKVLLTLPEQHRASYARLSSSPLLMLEQLLMNMKVDWATTAVQTLHQLLAGQDIG-------------FTLDEVDSLLSRYAGKALDLPYPLREK-RSDSMIHLQEPVHQASDSETLSRSSSAEFSAAAAP------GSALVRSPSPKERAFPQTQPPVE--FVPPETPPARDQWVPDETESVCMVCCREHFTMFNRRHHCRRCGRLVCGSCSTKKMVVEG-FRENPTRVCDQCYSYYNKDTPEESPCQSEVPDSAKNESPPYSAVVRVPKATEVEWILSLSEEENELVRSEFYYEQAPSASLCIAILNLHRDSIACGHQLIEHCCRLSRGLT-NPEVDAGLLIDIMKQLLFSAKMMFVKAGQSQDLALCDSYISKVDVLHLLVAAAYRHVPSLDQILQPAAVTRLRNQLLEAEYYQLGVEVSTKTGLDSTGAWHAWGMACLKAGNLTVAREKFTRCLKPP-----------------------LDLNQLSHGSRLVQDVVEYLEST----------------------------------VRP-LVSLQDDDYFATLRELEATLRTQSLLLEAIPEGKIMNNTYYQECLFYLHNYSTNLAIISFYMRHNCLREALLHLLNKESPPEVFIEGIFQPSYKSGKLHTLENLLESID-PTLESWGAHLIAACQHLQKNSYYHILYELQQFMKDQVRAAMTCIRFFSHKAKSYTELGEKLSWLLKAKDHLK--------------IYLQETSRSSGRKKATFFRKKMTAADVSRHMNTLQLQMEVTRFLHRCES---------------AGTSQVTTLPLPTLFGNNHMKMEVACKVMLGGKNVEDGFGIAFRVLQDFQLDAAATYCRAARQLVEREKYGEIRQLLKCVS-ESGMAAKSDGDTILLNCLEAFKR--IPP--QELEGLIQAIHSDDNKVRAYLTCCKLRSAYLIAVKQEHSQAAALVQQVQQAAKSSGDSVVQDICAQWLLTSHSRGAHGSGSRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68DK2-1", "uniprot_id": "ZFY26_HUMAN", "id": "Q68DK2-1", "name": "Zinc finger FYVE domain-containing protein 26", "aln": "MNHPFGKEEAASQKQLFGFFCECLRRGEWELAQACVPQLQ-EGQGDIPKRVEDILQALVVCPNLLRCGQDINPQRVAWVWLLVLEKWLAREKKLLPVVFRRKLEFLLLSEDLQGDIPENILEELYETLTQGAVGHVPDGNPRRESWTPRLSSEAVSVLWDLLR-QSPQPAQALLELLLEEDDGTGLCHWPLQNALVDLIRKALRALQGPDSVPPGVVDAIYGALRTLRCPAEPLGVELHLLCEELLEACRTEGSPLREERLLSCLLHKASRGLLSLYGHTYAEKVTEKPPRATASGKVSPDHLDPERAMLALFSNPNPAEAWKVAYFYCLSNNKHFLEQILVTALTLLKEEDFPNLGCLLDREFRPLSCLLVLLGWTHCQSLESAKRLLQTLHRTQGPGCDELLRDACDGLWAHLEVLEWCIQQSSNPIPKRDLLYHLHGGDSHSVLYTLHHLTNLPALREEDVLKLLQKVPAKDPQQEPDAVDAPVPEHLSQCQNLTLYQGFCAMKYAIYALCVNS--HQHSQCQDCKDSLSEDLASATEPANDSLSSPGAANLFSTYLARCQQYLCSIPDSLCLELLENIFSLLLITSADLHPEPHLPEDYAEDDDIEGKSPSGLRSPSESPQHIAHPERKSERGSLGVPKTLAYTMPSHVKAEPKDSYPGPHRHSFLDLKHFTSGISGFLADEFAIGAFLRLLQEQLDEIS------SRSPPEKPKQ-ESQSCSGSRDGLQSRLHRLSKVVSEAQWRHKVVTSNHRSEEQPSRRYQP-ATRHPSLRR------GRRTRRSQADGRDRGS-NPSLESTSSELSTSTSEGSLSAMSGRNELHSRLHPHPQSSLIPMMFSPPESLLASCILRGNFAEAHQVLFTFNLKSSPSSGELMFMERYQEVIQELAQVEHKIENQ------NSDAGSSTIRRTGSGRS--------TLQAIGSAAAAGMVFYSISDVTDKLLNTSGDPIPMLQEDFWISTALVEPTAPLREVLEDLSPPAMAAFDLACSQCQLWKTCKQLLETAERRLNSSLERRGRRIDHVLLNADGIRGFPVVLQQISKSLNYLLMSASQTKSES-VEEKGGGPPR-CSITELLQMCWPSLSEDCVASHTTLSQQLDQVLQSLREALELPEP---RTPPLSSLVEQAAQKAPEAEAHPVQIQTQLLQKNLGKQTPSGSR----QMDYLGTFFSYCSTLAAVLLQSLSSEPDHVEVKVGNPFVLLQQSSSQLVSHLLFERQVPPERLAALLAQENLSLSVPQVIVSCCCEPLALCSSRQSQQTSSLLTRLG------TLAQLHASHCLDDLPLSTPSSPRTTENPTLER------------------KPYSSPRDSSLPALTSSALAFLKSRSKLLATVACLGASPRLKVSKPSLSWKELR------GRREVPLAAEQVARECERLLEQFPLFEAFLLAAWEPLR-GSLQQGQSLAVNLCGWASLSTVLLGLHSPIALDVLSEAFEESLVARDWSRALQLTEVYGRDVDDLSSIKDAVLSCAVACDKEGWQYLFPVKDASLRSRLALQFVDRWPLESCLEILAYCISDTAVQEGLKCELQRKLAELQVYQKILGLQSPPVWCDWQTLRSCCVEDPSTVMNMILEAQEYELCEEWGCLYPIP-----REHLISLHQKHLLHLLERRDHDKALQLLRRIPDPTMCLEVTEQSLDQHTSLATSHFLANYLTTHFYGQLTAVRHREIQALYVGSKILLTLPEQHRASYSHLSSNPLFMLEQLLMNMKVDWATVAVQTLQQLLVGQEIG-------------FTMDEVDSLLSRYAEKALDFPYPQREK-RSDSVIHLQEIVHQAADPETLPRSPSAEFSPAAPP------GISSIHSPSLRERSFPPTQPSQE--FVPPATPPARHQWVPDETESICMVCCREHFTMFNRRHHCRRCGRLVCSSCSTKKMVVEG-CRENPARVCDQCYSYCNKDVPEEPSEKPEALDSSKNESPPYSFVVRVPKADEVEWILDLKEEENELVRSEFYYEQAPSASLCIAILNLHRDSIACGHQLIEHCCRLSKGLT-NPEVDAGLLTDIMKQLLFSAKMMFVKAGQSQDLALCDSYISKVDVLNILVAAAYRHVPSLDQILQPAAVTRLRNQLLEAEYYQLGVEVSTKTGLDTTGAWHAWGMACLKAGNLTAAREKFSRCLKPP-----------------------FDLNQLNHGSRLVQDVVEYLEST----------------------------------VRP-FVSLQDDDYFATLRELEATLRTQSLSLAVIPEGKIMNNTYYQECLFYLHNYSTNLAIISFYVRHSCLREALLHLLNKESPPEVFIEGIFQPSYKSGKLHTLENLLESID-PTLESWGKYLIAACQHLQKKNYYHILYELQQFMKDQVRAAMTCIRFFSHKAKSYTELGEKLSWLLKAKDHLK--------------IYLQETSRSSGRKKTTFFRKKMTAADVSRHMNTLQLQMEVTRFLHRCES---------------AGTSQITTLPLPTLFGNNHMKMDVACKVMLGGKNVEDGFGIAFRVLQDFQLDAAMTYCRAARQLVEKEKYSEIQQLLKCVS-ESGMAAKSDGDTILLNCLEAFKR--IPP--QELEGLIQAIHNDDNKVRAYLICCKLRSAYLIAVKQEHSRATALVQQVQQAAKSSGDAVVQDICAQWLLTSHPRGAHGPGSRK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6NK88-1", "uniprot_id": "F6NK88_DANRE", "id": "F6NK88-1", "name": "Zinc finger FYVE domain-containing protein 26", "aln": "-MHPFGREEETSRRELFGFFRRCLQRGEWELAAACVSQLG-EARAEDPHSPRDIVKAIVTHPYPLRWETVGSPHRLAWYWLQVLER---PTEIKVSVSVKRELEFLLLLEELE-DIPQSVLKELHEAFLYSEEVKGKAPGDS----ASPLSAALLSCLRSLLTRQQPRLCHSLISFLSNGDPSR---DHTLQDAFIQHLTEQVKVPAKDRNRE--WVEQVCSVLALAPWGSDRSGAQLEPLWEGLWAAR---EGLMTEERILGCLLRPQSQALLMAYSSTALRLLKDKLLAEAPHTQ--VDLPDLERVMLGLCCHKDKRLAWKAIYFECLSSGKHFLEQVLLTGLDLIKREEFSKLETLLHSEFQPLSRLLLLLGWMHCQSLESAKTLLTVLHHRQPQSNDSALSDLACTLSCQLGVLEWCTQNNPG-ISHDALLSHLHMLDHHSALYVLHCLTPLAKFEEHKVLELLQR------TGDPSQVDSPS---SSVQRNITLFRGFCAMKYALYAISVNARTHAHTGSLDCEPLHELQTEAAQEDE----TAEGCSNLFQHYLSECQLYLEAVPALFRLELLENIFSLLFLSDSDFTQQTSTATETQPYTNTETSKPKSTKEVN-TAEHFLKAENEGER-----------------MDELNQINP--------QLGHLTSGCRGFLVDLNVMEGILRLVREGLEGVCGVGQEDGRALGADVELAESLGCSVTAETFSARLQRLSKYTAEAQWRLQIVTSNHGNGNDGLYLPSPLPSPALPLKRQGSGSSGTSSRRRRKHHRHRSERHVSSERQNGEVSTSTSDGGVCVSVVCRGTETCPCGGSHSWLVPAMLSPPESLLIACIRRGNYIEAQQVIAMYGLENSECAGELVFMDRYREVLIELAQVEQKIESQSLSTSSSSSEGLGTLGATPAGRTRMGSSSRLTLKSIGSAAAAGMAFYSISDVADRLMSTPSRPIPCLEDSYWLSQCTIDSPDFVRPLVEELSPAAMAAFDLSCCQCQLWKTSRQLLETAERRLSSFLEARGVRVDPKVPHANGIRGFPSVLQQISKILNKTSTNKGMSKTDCNGEENAVCSPFGCSAQEVLLSCHSTLTEESITIQQNLNQRLEVTLQTLSSATNTSVDSLVGSNLLTALAEQAALKQSELDCHPVRTAMKQLLQYLDQLCPLVPDGAPDRPDYIRSFFDYVNVLASVLVRSLGSEDQSTVVKLGNPLLLLLQSPAQLLSHLLFDRQVSPDRVLSLLQQERLRLSVQQVVVQRCCETLPLWDSRAVNFSQRVSGLNGGAFCPASIASILQQYAQDCSPSLDLSDPTTTSDPSSESEVSVEDVSAASTSLSTSPPSPSSSSPSSSFLLTPSALSFLKSRSPLVAALACLSASRGGVTRVTSSGWSGLPSYFRGSGRKEAVLDGEQISREGEALLKNFPILRMYLRTMAEPVLGVSLEADEGLGVALCGKPVVGMLFSGLQGNAAQAMAAEAFQQALNNGDLNRALDLLELYAQPCSQEGALRDKLLAFTALQESSSAEQLFRVRDWELRGRVVLQGLDRWPLQQCLDLLHFCLSDQNTKDPLREQLQQRKQELDMYQRMLRLQPSLPWETWQELREESTKNPESVFSQMLEAREFELCAQWVQLYSVS-----DQSGMQLQTEHLLYLLEHNHTEEAFQLLEALSD-SMGLEVSERALDRRPGLAACHFLSDYLTLHFQSQMTPARRRHIHALHLGSKVLLTLPEASRQDYFSLLSDPLLMLEQMLMNLKVDWAAVAITTLRSLLLAQDAG-------------ITTQHIDTLLADYARKALDFPYAPREWSRSDSVISLQDAFLQCPAQESCPSSPSHTPPPSTGG--------TPMQTPSSERRPSGKKIRPLATPFTPPEKTPDRKDWIPDHKQHICMVCQRERFTMFNRRHHCRRCGRLVCHSCSSKKMAVAG-FDE-PVRVCDQCYNFFHTDSDEE-LEQGEVAGSPSSIDEVLNGVLSLPEVSRKQYRLSPNPAENQQLKSEFYYEQAPSASLCVAILTLHSDHAACGQQLIDHCRSLSRKLT-NPEVDARLLTDVMRQLLFSAKLMFVNAGCTQEPALCDSYISKVDVLKILVTANYKYIPSLDDIQETAAVTRLRNQLLELEYYQLAVEVSTKSALDPNGVWQAWAMASLKAGNLSGAREKFVRCLKAP-----------------------VDRNQLNHGPRLLQEIIQHLEST----------------------------------VKLTLSQTMDEDILASLRELEEALSDS--APPEGTESKVQRCNFHQECLFYLFTYGTHLSLISFYLRHDCLKDALTYLQNKGCSDDVFLEGIFQPCLERGRLGALQGLLENLD-PTLETWGRYLLSACQLLQRRGHYHSLYQLQQFMMDHIRAAMTCIRFFSHGAQSYLQLGEQQRWLIRAKEHLR--------------TYLQEQ-QSRRKSHSSSFRKKMSSTDVSRHIHTIELQLEVTRFLHRCESSPSKTA---------VGSTYTGNSAPPTLFGNSPMKVDVACKVMLGGKNIEEGFGIAYRVIQDFQLEALAVYIRVGQRLVRQRQYSSVRQLHKCVG-ESGTASKHDCDAIVLSCVSVADK--SPADAKELETLILECKNPENKIKAYLQCSKLRAAYLQAVKLKLVKATPLIQEVMRAAESSGDSVMHDICRQWLSEHQEPSSKQR----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGP1-1", "uniprot_id": "ZFY26_DROME", "id": "Q9VGP1-1", "name": "Zinc finger FYVE domain-containing protein 26 homolog", "aln": "--------MEDQQEENMQQLLNLLPKDQRQIFEIFIQWLNGKSSGPIQLHQNALLTVLQASPYPA-------------------------------------LQLLQLLHERSKLHIGQIISTLLRQLLDGDVASP----------------------------------------------------------------------------------------RSLCVLANFPASVLEASTLRQKLMTRLVVDSITSEHLMLTMLARSDGQLLDDLLHEQQLTMRAQCSEAAPTKL------------LVLWLALNEREHFVASVCQHLKDFKCFQDVTLRNNLLILRLANEFALGSQTLEELGCLEKLLAEFDVSAVPEKLQEVHGFFYADFQRLSTLLNFLRPREISKTLRVDALLRAPGVLPLIHENGIHFKHQELHRLIEDTYKWQQLTPALKCHHQEEVEILSY-----------------------------YTALCHVYDVVLDQ-------------------------------------GEQTTKTKLVQLSVQLRQLHQLGALCSLLEDIFLLVFLRWEQLEPNSQRKGEDGENDEEDDEQYVDDDVASPPRPTAVHSQRTRYGFICR---------------SASLHALFTFLKAFVTKKIHSQDYKSAPEQQGRFQRLVDAISEALWKLG-----------VLQKIEQSLLKSAPSISCLLEPDQLLQLVQLHSTAKKKASSDDESRER--------SNHASSLNR-------RKARRQRRAVSFSGGVAGKASADGGLAMEQLRARAQLLSGSGSRKNSSVTSPCERSIIPKMLSTPEQLAIMALALKNFNDVKKIIETFHLEHSQLNRELHFMEQQQLVKQKLSAIYANYQILE-------------GQQANSGET--------TVEQIKGVAAKGFELSKIISVVDNFS-----------------------------------------------QAHRLQQSPELKALIQRHNTSAQQGFLQQFEERNLNALIICDLIVNLGFNREITSNLLLVIRRQQQQKKGGDEASNTPG-----SSELGAMNLLQNLCECMRLLERSGQQAALNELLSLKSYPLR---PAVLALQLQREAAFQTLYQKEPSEYSHGHELRSNANQFQQLRSR-----HNYYARFCTYVQQLARLLQLRDPNLEYHTTQLLRN-------DPYEVIGELIYECGITPLEIEASVAA--LHLNLVHVIALNICPQLSEEPTKR---------------------------------LPRVVAPQKQES----------------------------------------IHNYISQHNQLLAHILLAIQLGSLPDGDADVDFSFLG-----------HLVHLSEVNVLASVYDGNRVLAALNAYKLESARLDQLVTDQ--------EQLLQILLLGMSGQTDSPNRHKSRIDQLIGDLIEKDPRNIHLVVHMGN------------------------LGQRAQLLKEHFTRIPSSQQAKELIERTLHHRSAAKSIPTALRSELEHTLSDITIYARVSALLK---FESWPQAYDFGRQTPNVIFEQLLQRRRFGLCLEWSRVVYLAGSAGQQRVCLLTLLDALLELRDGEELDESLLGIVEMFPPNPLVNFLDTHKDKFRSLPLLQWVIDYLEGHAR------DPRLYRNYQLSLEFLRQMDTNERSPFWKLIRHPLLIVEQLVMNARFELLGKLLDAARSKLLKERPLGPCPYCFDKTGHVYDVQSSAGLGSGAGETPAKIRFQLGQT-TSEAFILLNFNSYQQDHFVGQDCLDLLLRIYASKALDYHVANVRAASEPSSLGTDVHNSLDSLCGAFVMPKQAPNRQQWTRDEEASHCMCCRRAAFTMLMRRHHCRRCGRVVCYACSTHRIRIPELYDELEVRICNDCAACSTPAKDQGDGTSSERSAISGQVSK------SSGRSDSCKWQLSGIITHDKLLREEFSYEHAPSVALSLSILRNHVEQRSCVDLLLFHCRKLEKLIVPNPEVDYGLVAKMINCLAFAAKVRGAPG-------ELENIREHSEIIMAVVQQGCESLIPTGPLNN-HNLRKLADALVEAEHWTLALEVHLKCGFATTGVMAAHGLACLRAGCYDAAREKFAHCMTRLSSEQLNSSICKNIFGVASTEAVLLPRKRPQRGPALLQEILQLIAAIPQVQTQPETLHRASLIRSSNTSLASLFTRRREPYVQPRPLQEPALNIMNALAGLKNLAKGQYGGQMPTSEESRRQERGFEESLHYVLTYGSHADILTFLMRREELRAALRYWQHQQLDADLFIHHIFYPQLANGGLNVLMDELQQLDDAQFTAWRLPLLQTCRHLEQQQQLSSLYQLQLLLKDPIRASMTCVKFYALQCENFQKLHANAQHLLSALRHLQGELDMAEWEHLQRQQARRNSVSSTASVRGACFAMQMDARALNGHINTIRRQLEVAKFLDKCEREQPPDEPLRTIQTLKQIRLESSRGTLPTLFEGAADRIQICILILMCGKNIDEGFGLAYGIMQDFKLAALKVFGATAKYLSRNQRLGEVERLLDCIGSNNGGDISTESDEILSIAINAAVHSSAPETKQMLDRLIKRIGSVELRVSSYIYIGQLKSAYLLANKHDR---LADIRRILRQAELTGQVHIKKLCDMKLQLSAAPTPL------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: : : . * :.: :: : * .. . . :: .: * *::* * .: . ::. * . : . :: . . : .*::: :* . ** : : : * * : : *.. * * : * . * ::: : * *: *. ** :. . . : : . * :: .* . . : : * . . * : ** .... :::*. : .:* : .: * : . .:**:** *::: :: :. : : : . . . . .:. . . :.. . : : :: : * * : : :. . . .:: : . : .:*:. . : .. .*.* :** : . . . .. . . .. . ::* *:*.**.* .: *: :.:::: : *: * ** *::: : * :*: : : : : :*.: *:: * ..** *: : .* .*.:.: *.: : . :* :*: .* : :.: :. : .: * : . : : :.. .* . . * : . : . : .*: * . . : * .:** : . . : * . .: :* * * . ** :* . . : * .. :::..*: : :.* .: : : * *.: :*:. * *. :: * .. ::..:. ::* : .. .:. * * . . : . :: *. : :: *: . :: * : .: : . : : *: :.. .: . : * . : *: :*:: :: :* :: * : * . : *. ::. :* :.: ** :* : :. . : . ** * : . :::: : : . ::. : *: .*. ::: :** * : : :. :.* : * : * **:::**::** :.: : : :. * : : * : . .. .: : : *::.* *: * :: ** . . *. * .* *.:* *. ** * * ***: **********:** :**:::: : * .*:*::* : . * . . . . :: *. .:: ::.** **:***.:*.::** * : :* . *: ** *.: :. ***** *: .::. * *:**: . . :. .: ::: :* . : . . : : : :* : *:* *:: *.:** * .: ..*. * .:*.*:** ***** :*:. . :: .:*. *:*:::: : : *: . : : :* *: . .: . . .:*.*.*: .*.:: :::* :*:. *: ** : :: ::*:. ** * * * .* . *:.:* . : :* *: :*: *::. **:** :: * :**:***::*:: .:.: :* : *: * **: :: * : : * :* : :. *::*:. *:**::**.:** . **** . ::::. ::: ***:::***:*: ::***:* * .: ..: * ...: ..:.:* .*:. :.* . : * *: .:.. : * : *: ** . : :: :*: :*::*** * * . . ::.: : *: :*: ::.:* * . ", "identical_positions": 310, "similar_positions": 658, "identity": "11.34%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3294", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N543-1", "uniprot_id": "OGFD1_HUMAN", "id": "Q8N543-1", "name": "Prolyl 3-hydroxylase OGFOD1", "aln": "MNGK-RPAEPGPARVGKKGKKEVMAEFSDAVTEETLKKQVAEAWSRRTPFSHEVIVMDMDPFLHCVIPNFIQSQDFLEGLQKELMNLDFHEKYNDLYKFQQSDDLKKRREPHISTLRKILFEDFRSWLSDISKIDLESTIDMSCAKYEFTDALLCHDDELEGRRIAFILYLVPPWDRSMGGTLDLYSIDEHFQPKQIVKSLIPSWNKLVFFEVSPVSFHQVSEVLSEEKSRLSISGWFHGPSLTRPPNYFEPPIPRSPHIPQDHEILYDWINPTYLDMDYQVQIQEEFEESSEILLKEFLKPEKFTKVCEALEHGHVEWSSRGPPNKRFYEKAEESKLPEILKECMKLFRSEALFLLLSNFTGLKLHFLAPSEEDEMNDKKEAETTDITEEGTSHSPPEPENNQMAISNNSQQSNEQTDPEPEENETKKESSVPMCQGELRHWKTGHYTLIHDHSKAEFALDLILYCGCEGWEPEYGGFTSYIAKGEDEELLTVNPESNSLALVYRDRETLKFVKHINHRSLEQKKTFPNRTGFWDFSFIYYE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QTC6-1", "uniprot_id": "F1QTC6_DANRE", "id": "F1QTC6-1", "name": "Prolyl 3-hydroxylase OGFOD1", "aln": "MPAKKRQNDSETGKKNKKEKRGELAAINADLKEDSVLKSMRDAWQKKRSFSNGCVQLDCEPFPHCQITDFLQSPSFVEGLQAELLQLNFNSKSNDLYKFQQSDDLKERKEHHISQIRSIIFGEFRVWLSEVLQVDLEATVDISCAKYEHTDVLLCHDDELEGRRVAFILYLVPPWECKDGGTLDLFNTDEHCQPMSVVKSLLPCCNSLVFFEVSPVSFHQVAEVLSEEKCRLSLSGWFHGPSLPRPSRYIEPSAPRHAHIPRDETLLFEWVNEMYLDPRYQARVQQEFEDSSEICLPSFLQEEKLRQVRSALQSSEIQWEKRGPPNKRCYSCADLQSIPSCVQECWELLSSEAFFILLSNLTGLSLHYLCTNEDDGENEEGKSETENRDTEG-----------------DAQAGGSSTEADASSRENKKDKGPPSCVGEVRRWAHGDYTLLHDSVKREYALDLQLHMGCAGWKAEFGGFTSYIAHDEDEELLTVYPEDNSLALVYRDKDTLKFIKHINNSSTS------HTTAFYDFSFNYFES", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .* * :. ..: .** *: :* :. :.*::: *.: :**.:: .**: : :* :** ** *.:*:** .*:**** **::*:*:.* *************:*:* *** :*.*:* :** ***:: ::***:*:*:******.**.************:**********: . ******:. *** ** .:****:*. *.**************:*******.***:*********.**..*:**. ** .***:*. :*::*:* *** **.::*:***:**** * .**: **: :* .**: ..::*..******* *. *: ..:*. ::** :*: ***:*:****:***.**:*...*:* *:: ::** : ** ::* ....*:.:....*.**:.. * * **:*:* *.***:** * *:**** *: ** **:.*:********:.******** **.*********::****:****: * . : *.*:**** *:* ", "identical_positions": 286, "similar_positions": 156, "identity": "52.57%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3299", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C0K5-1", "uniprot_id": "GDC_MOUSE", "id": "Q8C0K5-1", "name": "Mitochondrial coenzyme A transporter SLC25A16", "aln": "MAALVAAAALAAAEPAPAVPQAAGSGGPTSRRDF-YWLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNRHYKH-----LGVLSTLRAVPQKEGYLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTFITTKLGVSGHVHRLMAGSMAGMTAVICTYPLDVVRVRLAFQVKGEHTYSGIIHAFKTIYAKEG---------------GFLGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLS--YAPALLGRPSSDN-------PNVLVLKTHINLLCGGVAGAIAQTISYPFDVTRRRMQLGAVLP---EFEKCLTMRETMKYVYGQHGIRRGLYRGLSLNYIRCIPSQAVAFTTYELMKQFFHLN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16261-1", "uniprot_id": "GDC_RAT", "id": "P16261-1", "name": "Mitochondrial coenzyme A transporter SLC25A16", "aln": "MAALVAAAALAAAEPPPAVPQAAGSGGPTSRRDF-YWLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKH-----LGVLSALRAVPQKEGYLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTFITTKLGVSGHVHRLMAGSMAGMTAVICTYPLDVVRVRLAFQVKGEHTYSGIIHAFKTIYAKEG---------------GFLGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLS--YAPTLLGRPSSDN-------PNVLVLKTHINLLCGGVAGAIAQTISYPFDVTRRRMQLGAVLP---EFEKCLTMRETMKYVYGHHGIRRGLYRGLSLNYIRCIPSQAVAFTTYELMKQFFHLN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16260-1", "uniprot_id": "GDC_HUMAN", "id": "P16260-1", "name": "Mitochondrial coenzyme A transporter SLC25A16", "aln": "MAAATAAAALAAADPPPAMPQAAGAGGPTTRRDF-YWLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKH-----LGVFSALRAVPQKEGFLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRLMAGSMAGMTAVICTYPLDMVRVRLAFQVKGEHSYTGIIHAFKTIYAKEG---------------GFFGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLS--HAPTLLGRPSSDN-------PNVLVLKTHVNLLCGGVAGAIAQTISYPFDVTRRRMQLGTVLP---EFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELMKQFFHLN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6P1-1", "uniprot_id": "A0ACD6B6P1_DANRE", "id": "A0ACD6B6P1-1", "name": "", "aln": "----MTTEAVSSG----ARPQIP---APVQRDGY-YWLRSFTAGGVAGCCAKSTIAPLDRVKILLQAQNPHYKH-----LGVFATIKAVPKKEGFLGLYKGNGAMMIRIFPYGAIQFMAFDNYKKFLHTKVGISGHVHRLMAGSMAGMTAVICTYPLDVIRARLAFQVTGHHRYSGIRHAFQTIYHKEG---------------GISGFYRGLIPTIIGMAPYAGFSFFTFGTLKTLGLT--HFPEQLGKPSLDN-------PDVLVLKTQVNLLCGGVAGAIAQTISYPLDVARRRMQLGASLP---DHDKCCSLTKTLKHVYSQYGVKKGLYRGLSLNYIRCVPSQAVAFTTYEFMKQVLHLN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38702-1", "uniprot_id": "LEU5_YEAST", "id": "P38702-1", "name": "Mitochondrial coenzyme A transporter LEU5", "aln": "----MTRDSPDSNDSYKHINKNTTQKTSFDRNSFDYIVRSGLAGGISGSCAKTLIAPLDRIKILFQTSNPHYTKYTGSLIGLVEAAKHIWINDGVRGFFQGHSATLLRIFPYAAVKFVAYEQIRNTLIPSKEFESHWRRLVSGSLAGLCSVFITYPLDLVRVRLAYET--EHKRVKLGRIIKKIYKEPASATLIKNDYIPNWFCHWCNFYRGYVPTVLGMIPYAGVSFFAHDLLHDVLKSPFFAPYSVLELSEDDELERVQKKQRRPLRTWAELISGGLAGMASQTAAYPFEIIRRRLQVSALSPKTMYDHKFQSISEIAHIIFKERGVR-GFFVGLSIGYIKVTPMVACSFFVYERMKWNFGI-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . . * .: * :** ***::*.***: :*****:*:*:*: * **.: :*:. : : : ::* *:::*:.* ::*****.*::*:*::: :. : .. ...* :**::**:**: :*: *****::*.***::. .* : : ::.** : . .**** :**::** ****.***:.. *: : : . * : . * *: : *:* :*:.**:** :** :**::: ***:*:.: * .* :: . : :: . *:: *:: ***:.**: * * :* .** ** : : ", "identical_positions": 105, "similar_positions": 120, "identity": "28.77%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3306", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PCN7-1", "uniprot_id": "HLTF_MOUSE", "id": "Q6PCN7-1", "name": "DNA-dependent ATPase/E3 ubiquitin-protein ligase HLTF", "aln": "MSYTFTRGPVWKYSQSVQYGSHENIPRLSYSTFLPHFEFQDIIPPDDFLTSDEEQDLVLFGTMRGQVVGLRYYTGVVNNNEMVALQREPNNPYDKNAIKVNNVNGNQVGHIKREIAAAVAYIMDNKLAQVEGVVPFGASNTFTMPLYMTFWGKEENRNVVLEQLKKHGFKLGPTPKTLGSSLENAWGSGRAGPSYSRPAHVAVQMTTDQLKTEFDKLFEDLKEDDRTVEMEP--AEAIETPLLPHQKQALAWMIARENSKELPPFWEQRNDLYYNTITNFSVKERPENVHGGILADDMGLGKTLTAIAVILTNFDDGRPLLSKRGK-KNHPGKEY--KDETIKRRGSNMDKKEDGHS-ESSTCGEEPSISGTPEKSSCTLSQLSSVCPKRRKISVQYIESSDSEEIETSELPQKMKGKLKNVQLNTKSRVK-GSSKVKEDSKF--ALTFFAS--ATQRKMLKKGMSMMECSEACDTGERTRATLIICPLSVLSNWIDQFGQHVKSEVHLNFYVYYGPDRIRD-SAWLSKQDIILTTYNILTHDYG------------TKDDSPLHSIKWLRVILDEGHAIRNPNAQQTKAVLELEAERRWVLTGTPIQNSLKDLWSLLSFLKLKPFID-------------------------------REWWYRIIQRPVTTGDEGG-----LRRLQSLIKNITLRRTKTSKIKGKPVLELPERKVFIQHITLSEEERKIYQSVKNEGKAAIGRYFTEG-----------------TVLAHYAD--------------------------VLGLLLRLRQICCHTHLLTNGMSSSGPSRSDTPEELRKMLIE---KMKIILSSGSDEECAICLDSLTFPVITHCAHVFCKPCICQVIH---SEQPHAKCPLCRNEIHGDNLLECPPEELACD------SDKESSMEWKSSSKINALMHALIELRTKDPNIKSLVVSQFTTFLSLIETPLKASGFVFTRLDGSMAQKKRVESIQRFQNTEAGSPTIMLLSLKAGGVGLNLCAASRVFLMDPAWNPAAEDQCFDRCHRLGQKQEVIITKFIVKDSVEENMLKIQNTKRDLAAGAFGTKKTDANDMK--QAKINEIRTLIDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JVH5-1", "uniprot_id": "A0A0G2JVH5_RAT", "id": "A0A0G2JVH5-1", "name": "", "aln": "MSWKFKRDSVWKYSQSAQYGAHENIPRLSYPPFFPRFEFQDIIPPDDFQTSDEELDLVLFGTMRGQVVGIRYYTGVVNNNEMVALEREPNNPYDKNAIKVNNVNGNQVGHLKRDLAAALAYIMDNKLAQVEGVVPFGASNTFTMPLHMTFWGKEENREVVLDHLKKHGFKLGPTPKTVGSSLENTWGSGRAGPSYSRPVHVAVQMTTEQLKTEFDKLFEDLKEDDRTIEMEP--AEAVETPLLPHQKQALAWMIARENSKELPPFWELRNDLYYNTITNFSVKERPENVHGGILADDMGLGKTLTAIAVILTNFDDGRPLLGKRGK-ESHPGKEY--KDETVKLRGSNTNKTTDGHS-EPSACSEEPSISDVSEKS--NVSDLFSFFSKRRKISVQSTESSESEEIETSKLSQKMKGKLKNTQLDTKSKVK-GSSKIKEDTQFALALTYFGP--ATKKKMLKKGTSVMESSKKCDTGERTRTTLIICPLSVLSNWIDQIGQHIKSEVDLNLYVYYGPDRIRD-STWLSKQDIILTTYNILTHDYG------------TKDNSPLHSIKWLRVILDEGHAIRNPNAQQTKAVLELEAERRWVLTGTPIQNSLKDLWSLLSFLKLKPFTD-------------------------------REWWHRIIQRPVTTGDEGG-----LRRLQSLIKSITLRRTKTSKIKGKPVLELPERKVFIQHITLSVEERKIYQSVKNEGKATIARYFTEG-----------------TVLAHYAD--------------------------VLGLLLRLRQICCHVHLPTNGTSSSDPSRSDTPEELRKMLVT---KMKLILSSGSDEECSICLDSLTFPVITHCAHVFCKPCICQVIQ---REQPHAKCPLCRSNIHGHNLLECPPEELACD------SDNKSDMEWTSSSKINALMNALIELRTKDPNIKSLVVSQFTTFLSLIETPLKASGFVFTRLDGSMAQKKRVESIQCFQNTDAGSPTIMLLSLKAGGVGLNLCAASRVFLMDPAWNPAAEDQCFDRCHRLGQKQEVIITKFIVKDSVEENMLKIQNMKRELAAGAFGTKKTDADEMK--QAKINEIRTLIDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14527-1", "uniprot_id": "HLTF_HUMAN", "id": "Q14527-1", "name": "DNA-dependent ATPase/E3 ubiquitin-protein ligase HLTF", "aln": "MSWMFKRDPVWKYLQTVQYGVHGNFPRLSYPTFFPRFEFQDVIPPDDFLTSDEEVDSVLFGSLRGHVVGLRYYTGVVNNNEMVALQRDPNNPYDKNAIKVNNVNGNQVGHLKKELAGALAYIMDNKLAQIEGVVPFGANNAFTMPLHMTFWGKEENRKAVSDQLKKHGFKLGPAPKTLGFNLESGWGSGRAGPSYSMPVHAAVQMTTEQLKTEFDKLFEDLKEDDKTHEMEP--AEAIETPLLPHQKQALAWMVSRENSKELPPFWEQRNDLYYNTITNFSEKDRPENVHGGILADDMGLGKTLTAIAVILTNFHDGRPLPIERVK-KNLLKKEYNVNDDSMKLGGNNTSEKADGLSKDASRCSEQPSISDIKEKSKFRMSELSSSRPKRRKTAVQYIESSDSEEIETSELPQKMKGKLKNVQSETKGRAKAGSSKVIEDVAFACALTSSVP--TTKKKMLKKGACAVEGSKKTDVEERPRTTLIICPLSVLSNWIDQFGQHIKSDVHLNFYVYYGPDRIRE-PALLSKQDIVLTTYNILTHDYG------------TKGDSPLHSIRWLRVILDEGHAIRNPNAQQTKAVLDLESERRWVLTGTPIQNSLKDLWSLLSFLKLKPFID-------------------------------REWWHRTIQRPVTMGDEGG-----LRRLQSLIKNITLRRTKTSKIKGKPVLELPERKVFIQHITLSDEERKIYQSVKNEGRATIGRYFNEG-----------------TVLAHYAD--------------------------VLGLLLRLRQICCHTYLLTNAVSSNGPSGNDTPEELRKKLIR---KMKLILSSGSDEECAICLDSLTVPVITHCAHVFCKPCICQVIQ---NEQPHAKCPLCRNDIHEDNLLECPPEELARD------SEKKSDMEWTSSSKINALMHALTDLRKKNPNIKSLVVSQFTTFLSLIEIPLKASGFVFTRLDGSMAQKKRVESIQCFQNTEAGSPTIMLLSLKAGGVGLNLSAASRVFLMDPAWNPAAEDQCFDRCHRLGQKQEVIITKFIVKDSVEENMLKIQNKKRELAAGAFGTKKPNADEMK--QAKINEIRTLIDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BAK6-1", "uniprot_id": "A0A8M2BAK6_DANRE", "id": "A0A8M2BAK6-1", "name": "", "aln": "--MQSSSSSTASSSTPPRYAFIDFMDVG--STMTLSQELANLT--EDAGQELEAEGNVLFGSIQGLIVGLRYYTGAVNKGEMVSLVREPHNPYDRNAVMVANVYGSQVGHIKKELAAAMAYIMDNKLARVEGIVPYGEKNKFSMPVILTFWGKEENREVVNNLMIGFGFNLDFR----GGSSQTSLGRDLLGLS---TKLSAIPLSAEELKNAFDKLFDDLMED-KTKEMEP--AEAVCTPLLSHQKQALSWMSSRENSNDLPPFWEENKGLYFNVLTNFAVKKRPEKVLGGILADDMGLGKTLTTIALIVSNFHNGKPLPLEKCKGPSMPSAKR--KQATSKEKGVDSEESQESMG----------------------------LSPLKRLHDDTVRENG----------PQKKTKTTKKKSANTKKAVV-----LLDDVEFAAALECSSSQVVPSKKCVKKSSVPSEIS----AGSVARATLIVCPLSVLSNWLDQFEQHIRTDVTVKVYLYYGSERNRS-VSLLSEQDVVLTTYNVLSSDFG------------NKASSPLHNVKWLRVVLDEGHVVRNPNALQSKAVLELQSERRWILSGTPIQNSLKDLFMLLSFLKLKPFDV-------------------------------KEWWSRIIQRPVTMGDRVG-----LKNLQALVKGITLRRTKNSKVGGRTLVQLPERRVFVQYVTLSGMEREKYERVKGEGKNIVGRYFQEG-----------------TFMANYAD--------------------------VLTILMRLRQCCCHPSLVGNYTAADVPG---TPSELRERLIQ---KITLVLNSGSDEECAICLDSLRQPVITYCAHVFCRPCICEVIR---SEKEQAKCPLCRAQIKTKELVEYPGEQAETR------SDTG--ENWRSSSKALALMSNLLKLRNEDPTVKSMVVSQFTGFLDVLEVALREYGFSFTRLDGSLIQRARAKAIEDFQDSTPGSPTIMLLSLKAGGVGLNLTAASQVFVMDPAWNPAAEDQCVDRCHRLGQSRDVVITKFIVKDSVEENMVKIQKKKQELVDKAFGVK--NSQDAK--QARIDDIRALMEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P31244-1", "uniprot_id": "RAD16_YEAST", "id": "P31244-1", "name": "DNA repair protein RAD16", "aln": "------------------------MQEGGFIRRRRTRSTKKSVNYNELSDDDTAVKNSKTLQLKGNSENVNDSQDEEYRDDATLVK----SPDDDDKDFIIDLTGSDKERTATDENTHAIKNDNDEIIEIKEERDVSDDDEPLTKKRKTTARKKKKK------------------------------TSTKKKSPKVTPYERNTLRLYEHHPELRNVFTDLKNAPPYVPQRSKQPDGMTIKLLPFQLEGLHWLISQEES----------------------------IYAGGVLADEMGMGKTIQTIALLMNDLTKS--------------------------------------------------------------------------------------------------------------------------------------------------------------------PSLVVAPTVALMQWKNEIEQHTKG--QLKIYIYHGASRTTD-IKDLQGYDVVLTTYAVLESVFRKQNYGFRRKNGLFKQPSVLHNIDFYRVILDEAHNIKDRQSNTARAVNNLKTQKRWCLSGTPLQNRIGEMYSLIRFLNINPFTKYFCTKCDCASKDWKFTDRMHCDHCSHVIMQHTNFFNHFMLKNIQKFGVEGPGLESFNNIQTLLKNIMLRRTKVERADD---LGLPPRIVTVRRDFFNEEEKDLYRSLYTDSKRKYNSFVEEG-----------------VVLNNYAN--------------------------IFTLITRMRQLADHPDLVLKRLN------------------------NFPGDDIGVVICQLCNDEAEEPIESKCHHKFCRLCIKEYVESFMENNNKLTCPVCHIGLSIDLSQPALEVDLDSFKKQSIVSRLNMSGKWQSSTKIEALVEELYKLRSNKRTIKSIVFSQFTSMLDLVEWRLKRAGFQTVKLQGSMSPTQRDETIKYFMN--NIQCEVFLVSLKAGGVALNLCEASQVFILDPWWNPSVEWQSGDRVHRIGQYRPVKITRFCIEDSIEARIIELQEKKANMIHATINQDEAAISRLT--PADLQFLFNN---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VHY2-1", "uniprot_id": "Q9VHY2_DROME", "id": "Q9VHY2-1", "name": "Transcription termination factor 2", "aln": "MESSSPSDTTEIHKQSCSIQDQSSVPVPDSSGEINNWMEPEPVDSLELSGEYADNESAIFVSASEYNEKKAQIDQLVQKILTMEQQQRQLEENASETKELCDLK-LHLEKLNARLEALGEFLDTLRLREDQQEIKIEDNSELVDHTEQPKWSN-------------------------------LYSGLNRYRQKANHTAAQFYQHKSNIIDSLKTLYEPIQPRPAIDDLEK-QPALLLVRLLKHQQSCLKWMQFRERQ----------------------------KISGGILADDMGLGKTLSMIALILASEETKNRKREEKKKALTLKWTQEFNRVYCKEIRKISMFDDEEESG----------------------------------------------KEEEQYEPPEKRTCHVKTKKINQFRILD----DDDNDAGDKAVVEDEQKDLLAKTPEPEVFSSDEEEEHLSNGRYPSANTLVVCPMSVMCQWAHEVASKVAQN-AIRVLTFHGPNRHEIGIEAFRSYDLVITSYNLVVNELKR-----------YGNTSPLFAVYWNRVILDEAHIIRNSKTNCCNSVCQLRAHCHWALTGTPVQNRGVDVFALLRFVNVPNFQD-------------------------------LQQWKKNLNESMLG----------HRRLNFIIKPLMLRRTKQKLQASGDMPALPSLKIELICVQLSKTEMAVYQILSAISKKIFTQFLLQREKGNSDLNYYSLERTPQFIAGHMSDERYNEIYERFLKSLGYNPGEKILGIYILVLLLRLRQFCCHPGLMIGMLRGALTAEDVQNVKVDASDVEGQLKMDVLAELDKFDETDSEDDCCDEEDSTRRDGNFKLEVIKDEIKE--ENVPWDSGDDLPTASSFEDQLDSARALKLLN------PQNPIFQFIRPSAKLKMVIDKLEELLTG-TNDKIIVTSQWVSYLAIVRKRLQDLSWETLDFNGQLTAKEREIVLRDFNAN--NEKRVLLLSLTAGGVGLNLNVANHMLIVDLHWNPQLERQAQDRIYRYGQTKPTFIYRYMCQDTVEQRIKSLQDCKLEIAKVVLPEEGGEVTKCVGGGLNLAELKKLFEM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . . . : : :: . : .: . : .. . : . : : .:: : . . : ** .* . * *: :*.. **:***:**:***: **::: . :*::.* .: :* .:. .: :.. ::*..* : *:::*:* :: * *. : : **:***.* ::: :: .:* :*.:. :* *:***:** ::: *: *::: * : : : : . : ..:: ::* : ***** . . ** : : :. * *. : .: :. : . : :: :: :: *:** . * * . . * : * * : :. : . . . .*:* :: * .* . . * :* **:. * ::. *: .: ::*.: * :. * . ::*:**.****.*** *.:::::* *** * *. ** :* ** : . * :: :*::* .: .:*. * :: .: . : : ", "identical_positions": 104, "similar_positions": 197, "identity": "9.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-333", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6UXN9-1", "uniprot_id": "WDR82_HUMAN", "id": "Q6UXN9-1", "name": "WD repeat-containing protein 82", "aln": "---MKLTDSVLRSFRVAKVFRENSD---KINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSP-VDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAG-VNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGG----YANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGK-------HTGPITCLQFNPKFMTFASACSNMAFWLPTIDD--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BFQ4-1", "uniprot_id": "WDR82_MOUSE", "id": "Q8BFQ4-1", "name": "WD repeat-containing protein 82", "aln": "---MKLTDSVLRSFRVAKVFRENSD---KINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSP-VDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAG-VNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGG----YANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGK-------HTGPITCLQFNPKFMTFASACSNMAFWLPTIDD--------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R565-1", "uniprot_id": "M0R565_RAT", "id": "M0R565-1", "name": "WD repeat-containing protein 82", "aln": "---MKLTDSVLRSFRVAKVFRENSD---KINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSP-VDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAG-VNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGG----YANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGK-------HTGPITCLQFNPKFMTFASACSNMKWWLPCYPVS-------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NV31-1", "uniprot_id": "WDR82_DANRE", "id": "Q6NV31-1", "name": "WD repeat-containing protein 82", "aln": "---MKLTDSVLRSFRVAKVFRENSD---KINCFDFSSNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHNKRVVALSMSP-VDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAG-VNSEMVKLYDLRSFDKGPFATFKLQYERTCEWTGLKFSNDGKLILVSTNGGTLRVLDAFKGAVLHSFGG----YNNSKGVILEASFTPDSQFIMIGSEDGKIHVWNAESGMKVALLDGK-------HTGPVTCLQFNPKFMTFASACSNMAFWLPTIDD--------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLN1-1", "uniprot_id": "WDR82_DROME", "id": "Q9VLN1-1", "name": "WD repeat-containing protein 82", "aln": "-MKIKLIDSVVRSFKVAKIFRENTD---KINAIDFAPNGEHLISCSEDDQIVIYDCEKGTQSRTVNSKKYGVDLIHFTHANNTAIHSSTKVDDTIRYLSLHDNKYLRYFPGHTKKVISLCISP-VEDTFLSGSLDKTLRLWDLRSPNCQGLMHLSGRPIAAYDPEGLIFAAG-VNSESIKLYDLRSFDKGPFVTFKLNQEKECDWTGLKFSRDGKTILISTNGSVIRLVDAFHGTPLQTFTG----YPNNKGIPIEASFSPDSQFIFSGSTDGRVHIWNADTGNKVSVLNGD-------HPGPVQCVQFNPKYMMLASACTNMAFWLPTSEEGL------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQD1-1", "uniprot_id": "Q9VQD1_DROME", "id": "Q9VQD1-1", "name": "WD repeat-containing protein 82", "aln": "-MSIRLNDDAMRQFRVAKVFPETKH---HTLAMEFSSDGLRLLVCDHS-ALSIFSSTRQVQVCKVPMHHYLPDVACFVQQDTRVLHSTSKHDYTIRCLDLNTRHCVRVFGGHAKTINRLASQPGGENVFISAGRDDQVYMWDIRVKTHTHRIKNLRRPLCAFDPEGLFLATS-SGTEGIQIRDVRMMGGEPSRKFVYQVNAKANWTQLQFAPNGKSLLLSTDHSWCFSVSAIDGTYQQSFTG----YSNKLRLPLDATYTPDSQFILSGADKGRIHIWRAADGFPVAVLKGN-------NMGPVRCMRFNPRATMFVSSDSRIVFWMPMANGVYDWVKRLKPGETISFTDETVQEEAVKAPRTIPMPKPKIETVWKIKRLNRKRACTGDEIVDLTNALHNNDSMEDGEIAED", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36104-1", "uniprot_id": "SWD2_YEAST", "id": "P36104-1", "name": "COMPASS component SWD2", "aln": "MTTVSINKPNLLKFKHVKSFQPQEKDCGPVTSLNFDDNGQFLLTSSSNDTMQLYSATNCKFLDTIASKKYGCHSAIFTHAQNECIYSSTMKNFDIKYLNLETNQYLRYFSGHGALVNDLKMNP-VNDTFLSSSYDESVRLWDLKISKPQVIIPSLVPNCIAYDPSGLVFALGNPENFEIGLYNLKKIQEGPFLIIKINDATFSQWNKLEFSNNGKYLLVGSSIGKHLIFDAFTGQQLFELIGTRAFPMREFLDSGSACFTPDGEFVLGTDYDGRIAIWNHSDSISNKVLRPQGFIPCVSHETCPRSIAFNPKYSMFVTADETVDFYVYDE----------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : .*: .* * . .::* :* :: .. . : ::.. . .: ::* . :.: . ::*:. : *: *.*. .: :* * ** : * .* ::.*:*.. *. : :**:: . : ::**.**.:* . . : : ::: : * : : .:*. *:*: :** :*:.:. . ..*: * : * .. .* ::**.:*:: .*:: :*. . :* . : .: ***: :.:: : ::: ", "identical_positions": 46, "similar_positions": 118, "identity": "11.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3374", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IYU8-1", "uniprot_id": "MICU2_HUMAN", "id": "Q8IYU8-1", "name": "Calcium uptake protein 2, mitochondrial", "aln": "MAAAAGSCARVAAWGGKLRRGLAVSRQAVRSPGPLAAAVAGAALAGAGAAWHHSRVSVAARDGSFTVSAQKNVEHGIIYIGKPSLRKQRFMQFSSLEHEGEYYMTPRDFLFSVMFEQMERKTSVKKLTKKDIEDTLSGIQTAGCGSTFFRDLGDKGLISYTEYLFLLTILTKPHSGFHVAFKMLDTDGNEMIEKREFFKLQKIISKQDDLMTVKTNETGYQEAIVKEPEINTTLQMRFFGKRGQRKLHYKEFRRFMENLQTEIQEMEFLQFSKGLSFMRKEDFAEWLLFFTNTENKDIYWKNVREKLSAGESISLDEFKSFCHFTTHLEDFAIAMQMFSLAHRPVRLAEFKRAVKVATGQELSNNILDTVFKIFDLDGDECLSHEEFLGVLKNRMHRGLWVPQHQSIQEYWKCVKKESIKGVKEVWK-QAGKGLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CD10-1", "uniprot_id": "MICU2_MOUSE", "id": "Q8CD10-1", "name": "Calcium uptake protein 2, mitochondrial", "aln": "MAAAAGRSAWLAAWGGRLRRGLAAGRRAVPTRGPLAAAVAGVALAGAGAAWHHGRVKAAAREGSRTVSAQKNYLG---PIEKLSLRKQRFMQFSSLEHDGEYYMTPRDFLFSVMFEQVERKTLVKKLAKKDIEDVLSGIQTARCGSTFFRDLGDKGVISYTEYLFLLTILTKPHSGFHVAFKMLDVDGNEMIERKEFVKLQKIISKQDGFKTVKTNETEYQDPTVKEPGVNTTLQVRFFGKRGEKKLHYKEFRRFMENLQTEVQEMEFLQFSKGLNFMRKEDFAEWLLFFTNTENKDIYWRNVREKLSVGESISLDEFKSFCHFTTHLEDFAIAMQMFSLAHRPVRLAEFKRAVKVATGQELSDNLLDTVFKIFDLDGDECLSHGEFLGVLKNRMHRGLWVSQQQSVQEYWKCVKKESIKGVKEAWRQQAGKGPF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q1LYC5-1", "uniprot_id": "Q1LYC5_DANRE", "id": "Q1LYC5-1", "name": "", "aln": "MATWARLGATLRSTAKSFWP-----VRSIFYRRAFGAGLLGSVVAGG---FIYYKNEPRWRLWPHIVYAEDEKQEQ-IMVPQMSMRRRRFNQFASMIYEDEPYMTPRDFLHSVLMEKVDHKLKKKVLTKADLDEMIKVASKAEAGNNLFRGIGDKGLISYTEYLFLLTIITKSDTGFHIAFKMLDIDGSETVDKMEFQKLKKVNGPKK--ELLRQGGTELSD---NADEVDTTLQVFFFGKDGNKKLQYKDFCRFMEDLQAEVQEVEFTQFSKGMKTMRREDFAEWLLHFTNEEDNEAYQDNMRKRIPTGQSITFDEFKEFCLFTYHLEDFAISVKMSIEGSKPIGLAQFKRAVMIATGHELSDNVLDTVFKLFDMDGDDCLSHKEFLAVMKDRVHRGLRVQPQYGVSGYWKCVKRETLEGAQEALR-KNGSPI-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: * * : : . : ::: .:.*.: * .:**. : : : . * . * *:.: : : *:*::** **:*: ::.* ********.**::*::::* * *:* *::: :. ..* .*..:**.:****:************:**..:***:****** **.* ::: ** **:*: . :. :: . * .: : ::****: **** *::**:**:* ****:**:*:**:** *****:. **:********.*** *::: * *:*:::..*:**::****.** ** *******:::* . :*: **:***** :***:***:*:******:**:***:**** ***.*:*:*:**** * : .:. ******:*:::*.:*. : : *. ", "identical_positions": 192, "similar_positions": 136, "identity": "44.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3375", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1L134-1", "uniprot_id": "AUP1_RAT", "id": "A1L134-1", "name": "Lipid droplet-regulating VLDL assembly factor AUP1", "aln": "MEPPPAPGPERLFDSHRLPSDGFLLLALLLYAPVGLCLLVLRLFLGLHVFLVSCALPDSVLRRFVVRTMCAVLGLVARQEDSGLRDHRVRVLISNHVTPFDHNIVNLLTTCSTPLLNSPPSFVCWSRGFMEMDR----RVELVESLKKFCASTRLPPTPLLLFPEEEATNGREGLLRFSSWPFSIQDVVQPLTLQVQRPLVSVTVSDASWVSELLWSLFVPFTVYQVRWLHPIRRQLGEENEEFALRVQQLVAKELGQIGTRLTPADKAEHMKRQRHPR---------LRPQSVQSSFPSPPSPSSDVQLTILAQRVKEVLPHVPLNVIQRDLARTGCVDLTITNLLEGAVAFMPEDVTEGSQSLPTASAPKFPSSGLVTP--QPTALTFAKSSWARQESLQERKQALYEYARRRFRERQAQEAE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70295-1", "uniprot_id": "AUP1_MOUSE", "id": "P70295-1", "name": "Lipid droplet-regulating VLDL assembly factor AUP1", "aln": "MEPPPAPGPERLFDSHRLPSDGFLLLALLLYAPVGLCLLVLRLFLGLHVFLVSCALPDSVLRRFVVRTMCAVLGLVARQEDSGLRDHRVRVLISNHVTPFDHNIVNLLTTCSTPLLNSPPSFVCWSRGFMEMDR----RVELVESLKKFCASTRLPPTPLLLFPEEEATNGREGLLRFSSWPFSIQDVVQPLTLQVQRPLVSVTVSDASWVSELLWSLFVPFTVYQVRWLHPIRRQLGEESEEFALRVQQLVAKELGQIGTRLTPADKAEHMKRQRHPR---------LRPQSVQSSFPSPPSPSSDVQLTTLAHRVKEVLPHVPLNVIQRDLARTGCVDLTITNLLEGAVAFMPEDVTEGSQSPPAPSAPKFPSSGLATP--QPTALTFAKSSWARQESLQERKQALYEYARRRFRERQAQEAE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y679-2", "uniprot_id": "AUP1_HUMAN", "id": "Q9Y679-2", "name": "Lipid droplet-regulating VLDL assembly factor AUP1", "aln": "MELPSGPGPERLFDSHRLPGDCFLLLVLLLYAPVGFCLLVLRLFLGIHVFLVSCALPDSVLRRFVVRTMCAVLGLVARQEDSGLRDHSVRVLISNHVTPFDHNIVNLLTTCSTPLLNSPPSFVCWSRGFMEMNG----RGELVESLKRFCASTRLPPTPLLLFPEEEATNGREGLLRFSSWPFSIQDVVQPLTLQVQRPLVSVTVSDASWVSELLWSLFVPFTVYQVRWLRPVHRQLGEANEEFALRVQQLVAKELGQTGTRLTPADKAEHMKRQRHPR---------LRPQSAQSSFPPSPGPSPDVQLATLAQRVKEVLPHVPLGVIQRDLAKTGCVDLTITNLLEGAVAFMPEDITKGTQSLPTASASKFPSSGPVTP--QPTALTFAKSSWARQESLQERKQALYEYARRRFTERRAQEAD---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PBN5-1", "uniprot_id": "AUP1_DANRE", "id": "Q6PBN5-1", "name": "Lipid droplet-regulating VLDL assembly factor AUP1", "aln": "METR---GIEQMFDFQRLPNDRFILLLLLLYAPVGFCLMLLRIFIGVHVFLVSCALPDSIVRRFIVRIMCSVLGLHVQQNSPRLRDKTTRLYVCNHVTHFDHNIINLLTSCNTPLLEGPVGFLCWARGFMELGQGVGSRTELTETLHRYCSSP--DTLPLLLFPEEDTTNGRTGLLKFSSWPFSVSDSIQPVALLVKRPFIAVSTPESSWLTELLWTFFVPFTVYHVRWLPPLSKEDGETHQEFASKVQGLLATELGVISTQITKADKAEHIKRKRHSAPQTAHSNLGARPRTVAQGFLGTSVGAEDSRIARLAQQVKEVLPDVPVSVITRDLLQTNCVDTTITNLLERTDQFNSEAAMTMPSGPGKAAASSTPSAMVSSPNLKPAAKSFGRSPIDRHMSLQERKEALYEYARRRYIEKHGLNKEDDL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * *::** :***.* *:** ********:**::**:*:*:************::***:** **:**** .:*:.. ***: .*: :.**** *****:****:*.****:.* .*:**:*****:. * **.*:*:::*:*. . ********::**** ***:*******:.* :**::* *:**:::*:..::**::****::*******:**** *: :: ** :*** :** *:*.*** .*::* ******:**:**. **::. ..* .. : * ::: **::******.**:.** *** :*.*** ******* : * .* ... .:*.. **: :* :*:* :*.:*. *: ******:*********: *::. : : ", "identical_positions": 218, "similar_positions": 121, "identity": "50.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3376", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q13618-1", "uniprot_id": "CUL3_HUMAN", "id": "Q13618-1", "name": "Cullin-3", "aln": "MSNLSKG------TGSRKDTKMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPNGLKTMCECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JLV5-1", "uniprot_id": "CUL3_MOUSE", "id": "Q9JLV5-1", "name": "Cullin-3", "aln": "MSNLSKG------TGSRKDTKMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSCYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIESGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F6NVK8-1", "uniprot_id": "F6NVK8_DANRE", "id": "F6NVK8-1", "name": "", "aln": "MASLPNPNMSNLKPGTKKDTKMRIRAFPMTMDEKYVNNIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLHSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERRGEVVDRGAIRNACQMLMVLGLEGRSVYEEDFEIPFLDMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFGRVPNGLKTMCECMSWYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVESILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRHHLQTSQVSLCGVDLTVRVLTTGYWPTQSATPKCNIPPSPRHAFEVFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPIKKEDGSDVGVGGALLTGSNTRKHILQVSTFQMTILMLFNNREKFTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIESGHVFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLRARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.*.: .*::********************.**************************************************************:******************************************************************************:*****************:************** ***:*************************************************************************************.******.************** ************************************* ****************************************************:******************************************************************************:***:: *** ***************************:******:********************************:******:****** :****************************:*******************************************.**:************************************************************************:*************************************", "identical_positions": 734, "similar_positions": 27, "identity": "94.83%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-338", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4QY64-1", "uniprot_id": "ATAD5_MOUSE", "id": "Q4QY64-1", "name": "ATPase family AAA domain-containing protein 5", "aln": "MVGVLSMAAAAAPLPVKDYEIEPCKKRRKDDDNSSCETITKYLSPIGKTGDKVFSPPKPSNILHYFRKTSLTTEKPQSTKAYKIKPSPPLLVGNSKDCKTPLEVFSNREFKRKRKRVSLSSQLNDIKIQDECPVEISNNDSKEDGGLS-DCVESSASVSLYKEHVEVLAESIE-DSRNQPNTKSSKK---KVNPKQCTTKSDDRILRKRKRSKVTGQSESVPLADELSLPEDGGKDSKLTKPSLAEEN------DSRTHATKRADLKESTITVSYEEFVKSHKAAKVEEIPDPAVPACVPSG-PGEAVKSGSEGELSGSCEPSPQLHLKTVTVLAQVHPTPPKKKGKIPPIFLKQKQPELENSLSDPENEQPVQKRKSNVVIQEGQLELAVLEAWNSEASVPKCSMEERQQFMRAFRQPPPDTLKNGFKKPLEKQKDPSEKSVHEG--DSSSEKIIENPNIQRVSSQGCLQSHADRGSFPKEKSKKPNKKGKKTRTT---AGGNREENIQKEKTAFSLKDEQDQNSLRRSVRQ-KSEVLKSNALLNSENLVCEDTAHDSVQ--MSLCNRNK-SRSSSTPTRDM-VTHHRAEPGSSLEYVSTRQPIRRSLRSCSTPATNALGGTESEDAQDTIPVKASTPKSARTSEKHNLYTAELIIVSSDSESPIRMKFTRISTPKKSKKSS----KKSETTEEELTSQKKKANSTSKNISKAKELIEEAKAFQIGGSK-TEETVVPLRRSSRHQARSAKEKSPEIDDSVIVIDSSPTSIREPEKSQKKLQNLNDVLGKKLNKSSKNVPGKMKIAPLFLAKRTKRAAIPVFDLDESSQDSSEQTQDCDVQFKAKRDFLMSGLPDLLKRQIAKKAAALDVYNAVSTSFQRVVHVQQKDDEYWLWHLKPPSCPLLTEFKELNTKVTDLSEYVVAFGEFSTLNPNPRS-NPAAVMMRTRKDFTKEVRNLLLEEIKCSNPEFSLEKYFPLLLKKRIEHQVLCEGHGKQASPQLQPDVSQKETKRKQVATGNQKSKRKRQNEYSVSPEEMKGRSKDLDERISSSCTNLDPSRDSGTEDMLWTEKYQPQNSNELIGNELAVKKLHSWLKDWKRRAELEERHNLKGKRDEKEEGILDLSDSTDFKGSSDDEE-NRLCNTVLITGPTGVGKTAAVYACAQELG-----FKIFEVNASSQRSGRQILSQLKEATQSHQVDKQGVN----SQKPCFFNNYNIGKSPKKLN---SPGKVVTSPRKLPPSSPKTSGQKRALLPKTLANYFKVSSKSKSNDDVGALMGDDKGVKNSSLEQRQLIQTKSTNANNSHIKDVGAEESNRKKATSLILFEEVDVIFD-EDAGFLNAVKTFMATTKRPVILTTSDP-TFSLVFDGCFEEIN--FSIPSLLNVASYLQVICLVENFRTDFKD--FVTLLTANACDIRKSILYLQFWIRSGGGILEERP---LSHCRENSRNT-LVCSEDGSDANINSKKPKRNRVALPRCDTGCAEALFGLKNIASPSQDLLSLLKHKITTKEEWQKLIQVLTEFHVQNIDLLHSNLEVILPLPVHVVPDVRGAYGFPVTTQASAP-ASMGHLTRKQSK-DQPLRKSQKRKQKK-MVILDDSDLFDTGLDFSGELPSLSPAPSLSVEDNIRRD--SNPEIKTQNSGFKP---HSVPQPPKTLAEKKCCMLVSHCLNSLSEFMENMSFIDALLTDP--GEQNELGRSAFHWTNGRVKSGLCDEFSLENRDRWAPQSAGELKATAEALSFTECSSTIS-KALESLNSCKQLERDPTNELTVCVSQRRHDACFRQSAANLDN---ADKRMAVIKSVFSSRSFLTLGNKQASIIDYLPTLRNICRTEKLKEQEKNKRRFLHYFEGIHLEIPEETITTLAADFP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A058-1", "uniprot_id": "D4A058_RAT", "id": "D4A058-1", "name": "ATPase family AAA domain-containing protein 5", "aln": "MVGVLTMAAAAAPPPVKDCEIEPCRKRRKDDDSSSCETITKYLSPIGKTEDKVFSPSKPNNILHYFRKTSPTTEKLQSTKECKLKPSPPLLVGNSKDCKIPLEVFSNRESKKKRKRVSLSHQLNDVKIENESPVEISNDDSKEDCGLS-DFVENSTSVFLYKKHVEALAESIQEDSRNQSNTMTSKKNSKKVNPKQGTTKNDGKTLRKRKHSQGTDQSESVLVADEISLPGEGGKDSRLTKASLTDENRTAHHVDSRAHATKIADLNESTITVSYEEFLKSHKTAKVEDIPDLAGPACVPSG-PSEAIKSGSEGEPE-SCEPSPHLHLKTVTVLAQVHPTPPKKKRKIPPIFLKQKQLELENSFSDPENEQTVQKRKSNVVVQEGQLELAVLEAWSSEASVPKCSMEERQQFMRAFRQPPSETLRNGLKKPLEKQKDPSEKSVNEG--DSNSEKIIENPNIQRVSNQDCSQAHADRGGFPKEKSKRPNKKGKKTRTT---AAGNREENMQKEKTAFSLKDNQDQNTLRRSVRQ-KSEVFKSSALLNSENLVSEDTARDSVK--PSLCDRNK-SRRGSTPTRDM-VTHGKAEPGSGLVNVSTPKPTRRSLRGSSTPTTVTLGGTESEDAQDTDPVKASTPKAARISEKPSLYTAELIIISSDSESPIRMKFTRISTPKKSKKSS----KKSERTKEELTSQKNKANNTSKKISKAKQLIERAKAFQVSGSK-AEETVVPLRRSSRHQTRLEREKSPETDDSVILIDSNPTSIRQPEKNQKKLQNLNDVLGKKLNKSSKKVPGKMKIAPLFLTKKTKRTAISAFDLDESSQDSSGQTQDCDVQFKAKRDFLMSGLPDLLKRQIAKRAAALDVYNAVSTSFQRVVHVQQKDDEYWLWHLKPPSCPLLTEFKELNTKVTDLSKCLVAFGEFSTLNPNPRS-NPAVVLMRTRKEFTKEVRNLLLEEIKWSNPEFSLGKYFPLLLKKRIEHQVLCEGHGKQASPQLQPDVSQKETKRKQVETGSQKSKRKKPNEYSVSPEKIKGKSKELDKRISSSCINLDPSKESGTEDMLWTEKYQPQNSNELVGNELAIKKLHSWLKDWKRRAELEERQNLKGKRDEKEE---DLSDGTDFKGSSDDEE-YRLCNTVLITGPTGVGKTAAVYACAQELG-----FKIFEVNASSQRSGRQILSQLREATQSHQVDKQGAN----SQKPCFFSNYNIGKSPKKLN---SPGKVITSPRKLPPLSPKTGGQKRALLPKTLANYFKVSSKSNNNEDVGARPGNDKGVKNSSLEQRQIIQTKSTNANNSNIKDFGAEESNRKNATSLILFEEVDVIFD-EDAGFLNAVKTFMATTKRPVILTTSDP-TFSLVFDGCFEEIN--FNIPSLLNVASYLQVICLVENFRTDFKD--FVTLLTANACDIRKSILYLQFWIRSGGGILEERP---LSHCRENSRNT-LVCSEHESDANINSKNTKRNRVALPRCDTGCAEALFGLKNIACPSQDLLSSLKHKITTKEEWQRLIQLLTEFHMQNVDLLHSNLEFILPLPVNMIPEVRGAYGFPVTTQASAP-ASMKLLNRKQSE-DQPLRKSQKRKQKK-MVTLDDSDLFDTSLDFSGELPSLSPAASSSEEDNTSRDRGSNPEIKTQNKGFKP---HSLPQPPKTLAEKKCCVLVSHCLNSLSEFMENMSFVDALFTDP--GEQNELGKSAFHWTNGKVKSGLCDEFSLENRDGWSPRSSEELKATAEALSFTKCSSTIS-KALESLNSCKQLGRDPTTELTFCVSQRSHDVCFRQSAANLYN---ADKRMAVIKSVFSTPSFLTLGNKQASIIDYLPTLRNICRTEKLKEQEKNKRRFLHYFEGIHLDIPEETITPLAADFP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96QE3-1", "uniprot_id": "ATAD5_HUMAN", "id": "Q96QE3-1", "name": "ATPase family AAA domain-containing protein 5", "aln": "MVGVLAMAAAAAPPPVKDCEIEPCKKRKKDDDTSTCKTITKYLSPLGKTRDRVFAPPKPSNILDYFRKTSPTNEKTQLGKECKIKSPESVPVDSNKDCTTPLEMFSNVEFKKKRKRVNLSHQLNNIKTENEAPIEISSDDSKEDYSLNNDFVESSTSVLRYKKQVEVLAENIQ-DTKSQPNTMTSLQNSKKVNPKQGTTKNDFKKLRKRKCRDVVDLSESLPLAEELNLLKKDGKDTKQMENTTSHAN-------SRDNVTEAAQLNDSIITVSYEEFLKSHKENKVEEIPDSTMSICVPSETVDEIVKSGYISESE-NSEISQQVRFKTVTVLAQVHPIPPKKTGKIPRIFLKQKQFEMENSLSDPENEQTVQKRKSNVVIQEEELELAVLEAGSSEAVKPKCTLEERQQFMKAFRQPASDALKNGVKKSSDKQKDLNEKCLYEVGRDDNSKKIMENSGIQMVSKNGNLQLHTDKGSFLKEKNKKLKKKNKKTLDTGAIPGKNREGNTQKKETTFFLKEKQYQN--RMSLRQRKTEFFKSSTLFNNESLVYEDIANDDLLKVSSLCNNNKLSRKTSIPVKDIKLTQSKAESEASLLNVSTPKSTRRSGRISSTPTTETIRGIDSDDVQDNSQLKASTQKAANLSEKHSLYTAELITVPFDSESPIRMKFTRISTPKKSKKKSNKRSEKSEATDGGFTSQIRKASNTSKNISKAKQLIEKAKALHISRSKVTEEIAIPLRRSSRHQTLPERKKLSETEDSVIIIDSSPTALKHPEKNQKKLQCLNDVLGKKLNTSTKNVPGKMKVAPLFLVRKAQKAADPVPSFDESSQDTSEKSQDCDVQCKAKRDFLMSGLPDLLKRQIAKKAAALDVYNAVSTSFQRVVHVQQKDDGCCLWHLKPPSCPLLTKFKELNTKVIDLSKCGIALGEFSTLNSKLKSGNSAAVFMRTRKEFTEEVRNLLLEEIRWSNPEFSLKKYFPLLLKKQIEHQVLSS--ECHSKQELEADVSHKETKRKLVEAENSKSKRKKPNEYSKNLEKTNRKSEELSKRNNSSGIKLDSSKDSGTEDMLWTEKYQPQTASELIGNELAIKKLHSWLKDWKRRAELEERQNLKGKRDEKHE---DFSGGIDFKGSSDDEEESRLCNTVLITGPTGVGKTAAVYACAQELG-----FKIFEVNASSQRSGRQILSQLKEATQSHQVDKQGVN----SQKPCFFNSYYIGKSPKKIS---SPKKVVTSPRKVPPPSPKSSGPKRALPPKTLANYFKVSPKPKNNEEIGMLLENNKGIKN-SFEQKQITQTKSTNATNSNVKDVGAEEPSRKNATSLILFEEVDVIFD-EDAGFLNAIKTFMATTKRPVILTTSDP-TFSLMFDGCFEEIK--FSTPSLLNVASYLQMICLTENFRTDVKD--FVTLLTANTCDIRKSILYLQFWIRSGGGVLEERP---LTLYRGNSRNVQLVCSEHGLDNKIYPKNTKKKRVDLPKCDSGCAETLFGLKNIFSPSEDLFSFLKHKITMKEEWHKFIQLLTEFQMRNVDFLYSNLEFILPLPVDTIPETKNFCGPSVTVDASAATKSMNCLARKHSEREQPLKKSQKKKQKKTLVILDDSDLFDTDLDFPDQSISLSSVSSSSNAEESKTG---DEESKARDKGNNPETKKSIPCPPKTTAGKKCSALVSHCLNSLSEFMDNMSFLDALLTDV--REQNKYGRNDFSWTNGKVTSGLCDEFSLESNDGWTSQSSGELKAAAEALSFTKCSSAIS-KALETLNSCKKLGRDPTNDLTFYVSQKRNNVYFSQSAANLDN---AWKRISVIKSVFSSRSLLYVGNRQASIIEYLPTLRNICKTEKLKEQGKSKRRFLHYFEGIHLDIPKETVNTLAADFP---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NDC2-1", "uniprot_id": "A0A8M1NDC2_DANRE", "id": "A0A8M1NDC2-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATMDSSLFPLAVVKIMNSSG-------------------------------------------------------------------------SVCNRRN---------FHAGVLQSEGNPQTQMHPKRNRLKLAKTYR-------------TSDNIVGNNPSHVTGSYESTTFCKGTFFTDAVRTTDDKDNLTQKEHFSQRVQ----------------------NSNKVTSKRTSNNMSVQLVCTPAKREHASSDSS----LKPAIDHFGSNKEGLTRFLQTEIDDGDHLIDQPKMNIGQIQETSKHDPIQNLRSSNNSTSSCREPPNVRTVKEMRLSWRKEIPSE----------------NSCELLKDIQKLNLQFPVQRFFTLLLKKGTSSMEESSALEAEMS-------------------------------------------------------------ENYKHHSDYCVQRKRKLELEDQYRTYKRYRMNKGIRFAIKD----------------FELFSDVLVNPHSKYTNRLSRTKCRQQQTTFCAIVTEPVQNDSVYQNQRLR-------------VDDVLWTDKYQPQQSSEVIGNSASVRQLHSWLKEWKTRADTEERRRRQDERRMKKEAAESWDCGDFVGDAVSIDQVKELCNTVLITGPSGVGKTAAVYACAQELG-----FKVFEVNSSALRCGRLLLSQLTEATQSHQMDLESIKPSAVESESGVINQSQIKPAPVSSTGKEAHRKVTTSPSKETSVCRSDSHNIRNPQPVKLTRFFKLSSK----KSLVKTSDGPERCKHATVEPDRLQKSGSG-CKSERGKESASKNQSRAIPVSLILFEEVDVIFP-EDVGFLTAIKTFMSTSKRPIILTTNDP-LFGARLKGHFDEIH--FRTPSLQTIRSYLQCLCAVENMKTDPEY--MAFLLCQNKGDIRQSILQLQLWVCSGGGSTELQI---LQNTLKCRSWTELKNS---------------RCLEILAEKTGAGLLYFIIGSLFSPKFSSQSFYLQEFSN-------------------------------------PNTKGEKSEGLMLQTSSNVHERKSACRGKTHRPKTISYPYSVKASD-------------------------------------------PSKQTNKLASEP------------RARGQSKSLIFQHVLCIGSFFDNMSFVDACLQKPSLSRTELCKTEALGWMGATLKDSLLDLQREEQIRQYFENSS-QLLAFVEVLSFHRCQTELSGIWTEAARLREKMSSERWEQVMASFSQPFGQKYLATCHCKFCEPRVAQKHRELASILNSSRKICCLRNKRAFFMDYLPTLRSICRSERIKGQHSIRR----SYYLSSLHLPRSTLELMAVDFP---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86BP6-1", "uniprot_id": "ELG1_DROME", "id": "Q86BP6-1", "name": "Enhanced level of genomic instability 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDVNCLTSEHIAPTTTTASPPGTPSKNAATDPVEPTS-PFVLRAPPSAKSKLILQNMEEVLNSVKQKHREKHKRKREEKRRAALMEDQKSTTEEVKAN----AKEKPQPLREKSSQENGLKNGRRRSSPLKSSTPVADNQSIMKHFAKAGKPENVGVSPVSTAKPKPTTN-------------------------VFEFMMNARNRSLGVNEGGAESPADQEIGSEAATPTTKRKLLLQEWNE-----RKGGAKRRLADEARGEFIELQMEQRAKRLRKMLTKTDAKEVTAPSSAPTDPTVKRLRGRPRSRRISSMDAQNQIVESKPPVVKAKDQDPGTEELLSKLSSPTKKRDS--------------LLGYFPKVESPKELAEKVIIAIETPPMETPKRRTLRRKSQQETPIVAESTPSSRPRRSCVGKARYDYDLETSPGKQQKAKPQKADESVEIIDLDNSNPAATP---KKLAPLFVRQLPKPSPDP-------------------SVLKARQAFLQSGVPDKIRQEQIRQKNFDQMYEDSYEVFPRLAHIGCESFGSKNGPLDIP---------------------------FALRAEEEYSEVTKALPANKRRAKASSITSCLPADFTSSKTLNKFNYATLPQLENKRGFVKLWKN-----DFDRFPTFKCYNQMREKYRHFSAIDSAQDTQQMGESLVVTRRTRRSMEQNMAQNEEEAKPPPSAPNGELLFTEKYKPLLFEQVLVNLTPVQELREFLSSWSGNGGSNRNSQ---------------GMDDTFDMSNDSASMGSSSNTMVLVGPSSSGKTNAVFTLANDMN-----FNVLEINAGMKRTGKKLIQELQEATQSHQIRKDGKAG-------GGSSQQLLQKLQK----------------------------------------------------------------------------------SGLKAKAAAVEPPSEVRKSLILIEDADILFDNLDAGFTDAIYTLAASSKRPVIVVATDPNCAHLQRLMQQNIIH--FQAPNALNISRFLAVLSLMENCPIELDE--LISVYLYNQQNLRKTLMELQFYIQSGGDSTRDRTGGGIKSPTKTS-------------------NSRLATVDGSRIHQRFFEFFTSPQNVQYRIPFPVDFSLLRLNL-------------------------------------PDLMASSAMLKEQQAAGGGSRTAAKRKSRSPKKAWLSSATGQKSDG----------------------------------------------------------------------------HSSSLATLASFYDNISVASLMDSDCS---------DRLQWHLSEEIGHLLVEQALQTG-----------------LATKECPYNLFDKPVQRFSICQHLGNG------VLRSDSAKSLDFEPALRSICR----SEKERAGLERKSSRFYHYLRNHTVNVTSFTTDYFDTACSTFQSAAP----------------SSEPTMEAEPKD-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12050-1", "uniprot_id": "ELG1_YEAST", "id": "Q12050-1", "name": "Telomere length regulation protein ELG1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKRHVSLSDILTGNKRKVRR-------------------QDALQITIDDENDTESGTFDARTAKHDDSSVIFLNHS-----------------------------------VVKPIEAVSTNHKSAKEFLMTKRTKEKCDDDDD--DLIVISDKSPKSETNCSKIALSQEHEDDISIISTSRIKSSLLNERASKIKNFLKHETTDTFKRLNSISKLNEIEPPLPLHQS-------------------------------------------------------------------------------------------------------------------------------IFPVGDKELSDRSVDIPLPFRTIPPLNHNFLPSDYESLKDK-------------------NSASCIPVRYQAPVLLGTNIKRNTTLTWPQLFKPVTLKQVLIEPKLK------------------LRIKNWIETSFHTLEKPTLRNRLLNRINPNKQQGSGDELANFIVPDLEEDE-----NLRPDFYRNGEANSSLSEFVPLMILHGNSIGKKTLIQTIMREIAGDDNSYQIYEVNSNMNRSKKDLLDILLDFTTTHYVK---------------------------------------------------------------------------------------------------------------------DSSKRKSDYGLVLFNDVDVLFKEHDRGYWAMISKLCEFSRRPLVLTCKDLSLVPSELIALASEQNSLFHTKKISTSTVYAFLTKYLKSLEIEVCDDWLRDVVKQNNADIRKCLMHLQFWCVDTEADLISSK---NRLPVLTS------------------------TLGSSVKDISQLTDLLSINDVIGQATLNRSMVRQEIDS---------------------------------------TTMTPEKVNTFQDQNLDDEMKLKFDYVIDYKLHLNDPNRQ------------------------------------------------------------------------------PLLPFELNIYQHIQEQLEARYSYVREANHRLDNEYLVNRFKKMTESTLNFLASRIPKYDHLQSARRTR----------NSKKISDILN--QFKGIYNDETLNENAEIDLLSATTQQIKAEINPFVFEIAKS---------DANVKNENKQIFELHSENVSERRYKDLVYQLSQEGVLKNVWFN----------ADPSIVVRKWEHLHSGFSKNK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : .. : :: : . . . : .: . . : . . . : ::. : . . * . : : ..* . :. . .. :. . . . . . .::: .. **. : : .:: ::: *:*:. * : ::. * : * :* : . .*:*:::.*::* * *: : .: ::**:::. .* . : * . . : :. : : : * ::*: :: **:: . : . .: . .: : : . : : :::. . . : . * . : : : : :: .. : .. . : . . . . . ", "identical_positions": 25, "similar_positions": 149, "identity": "1.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3389", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A929-1", "uniprot_id": "WDR81_RAT", "id": "D4A929-1", "name": "WD repeat-containing protein 81", "aln": "MAQGSRRRKVVLTAGAEGCSSSSGPDMEELLRCAERDLNIDARQLALAPGGTHVVALVSTRWLASLRERR--LGPCPRAEGLGEAEVRTLLQRSVQRLPQGWTRVEVHGLRKRRLS--YPLSRVLPFEEGSCSPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSTAPSAIPALDS--------------IRQALQRVYGCTFLPVGESMQCLSNVRDG------------PSRGSS-ACPSLLRAEALLES--PEMLYVVHPYVQFSLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLHHIAVDEKLCSELRLDLSAYEMPSEDENQEVSEEKDRTGVKSEKDGEGRPGCP-------------TCQKELRGLVLDWVHGRVSNFYYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPYG-RFRDLRKSKFRLNKGDKQLDFTYEMTRQAFVAG-------------------GAGSGEPLHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPATMERMQTWTPDECIPEFYTDPSIFCSIHPDMPDLDVPAWCSSNQEFVTAHRALLESWEVSQDLHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLTSYGVVQLFDQPHPQRLAGAPALAPEPPLIPRLLVQPIQEATGQEDIS---GQLINGAGRHVVEVTPCESG-WTRERPTAGEDDLEQATEALDS------------ISIPGKAGDQPG--------SSSSQASPGLLPFSAP----SGSRPGRRSKATGLD----SGEGDEGKIVLPEGFSPIQALEELEKVGNFLARGLGSQLEEPE---------KPQAQPPVYLQSLFHRDMQVLGVLLAEMVFATRVRILQP----DAPLWVRFEAVRGLCTRHSKDIPVSLQPVLDTLLQLSG---PKSPLVVKKGKLDPLFEYRPVSQGLPPPSPAQLLSPFSSVVPFPTYFPALHKFILLYQAR---------------------RVEDEVQGRELVFALWQQLGAVLN-EITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNTIKYLLKPLIGAYENP---------------------------CRLHGRFYLYTDCFVAQLVVRLGLQAFLIHLLPHVLQVLAGVEASQEEG----------KGLVGTTEDEENELPVPGPGSCAFGEEIQMGGQPAASSG-------LGLPDYRSGVSFHDQADLPDTEDFQAGLYVAESPQ-----------------PQEAEAVSLGQLSDKSSTSEASQGEERGGDDGGAPVDKNSVKSGDSSQDLKQSEGSEEE-EEEEEGCVVLEEEE--QDEVTGTSELTLSDTILSMETVVAPGDGRD-REEEEEPLPEQTEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGPTRQQFTVSCDDSPPLN-AGNIYQ------KRPVLGDIVSGPVLSCLLHIAHLYGEPVLTYQYLPYISYLVAPGSNSSPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRIS-HEVLLPVLSFLTSFVTGFPSGAQARTVLCVKTISLIALICLRIGQEMVQQHLSEPVAT-FFQVFSHLHELRQQDLQLDLKGCTEGQLPEATFSDGQRRPVDPTLLEELQKVFTLEMAYTIYVPFSCLLGD-IIRKIIPNHELVGELAGLYLESMSPSSL------RNPASMEPVTPSAGPEWN----PQSGSCLQDDG-----HSGTFGSVLVGNRIQIP-DSQPQSS------------GPLGS-----------ISGVGS-GGLSSR-------NEDNALKRELPRSAHGLSGNWLAYWQYEIGVSQQD-AHFHFHQIRLQSFPGHTGAVKCVAALSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLIYAQHRKSVFYVGQLEAPQYVVSCDGAVHVWDPFTGKTLRTVDPSDSRVPLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGG-LNPGLVRSLAVSPSGRSVVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVIVSSSSDHSLTVWKELEQKPTHHYKSASDPIHTFDLYGSEVVTGTVANKIGVCSLLEPPS--QATTKLSSENFRGTLTSLALLPTKRHLLLGSDNGIIRLLA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5ND34-1", "uniprot_id": "WDR81_MOUSE", "id": "Q5ND34-1", "name": "WD repeat-containing protein 81", "aln": "MAQGSRRRKVVLTAGSEGWSPSSGPDMEELLRSVERDLNIDARQLALAPGGTHVVALVSTRWLASLRERR--LGPCPRAEGLGEAEVRTLLQRSVQRLPPGWTRVEVHGLRKRRLS--YPLGGGVPFEEGSCSPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSTAPSALPALDS--------------IRQALQRVYGCTFLPVGESIPCLSNVRDGP----------CPSRGSP-ACPSLLRAEALLES--PEMLYVVHPYVQFSLHDVVTFSPAKLTNSQAKVLFLLFRVLRAMDACHRQGLACGALSLHHIAVDEKLCSELRLDLSAYEMPSEDENQEGSEEKNGTGIKSEKEGEGRTECP-------------TCQKELRGLVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPYG-RFRDLRKSKFRLNKGDKQLDFTYEMTRQAFVAG-------------------GAGSGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPATMERMQTWTPDECIPEFYTDPSIFCSIHPDMPDLDVPAWCSSNQEFVAAHRALLESWEVSQDLHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLTSYGVVQLFDQPHPQRLAGSPALAPEPPLIPRLLVQPIREATGQEDIS---GQLINGAGRLVVEATPCETG-WTRDRPGTGEDDLEQATEALDS------------ISLPGKAGDQPG--------SSSSQASPGLLSFSAP----SGSRPGRRSKAAGLD----PGEGEEGKIVLPEGFSPIQALEELEKVGNFLAKGLGSQLEEPE---------KPHAQPPVHLQSLFHRDMQVLGVLLAEMVFATRVRILQP----DAPLWVRFEAVRGLCIRHSKDIPVSLQPVLDTLLQLSG---PKSPMVSKKGKLDPLFEYRPVSQGLPPPSPAQLLSPFSSVVPFPPYFPALHKFILLYQAR---------------------RVEDEVQGRELAFALWQQLGAVLN-DITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANKYLLKPLIGAYESP---------------------------CRLHGRFYLYTDCFVAQLVVRLGLQAFLTHLLPHVLQVLAGVEASQEEG----------KGLVGTTEDEESELPVSGPGSCAFGEEIQMDGQPAASSG-------LGLPDYRSGVSFHDQADLPDTEDFQAGLYVAESPQ-----------------PQEAEAVSLGQLSDKSSTSEASQGEERGGDDGGAPADKNSVKSGDSSQDLKQSEGSEEE-EEEE-GCVVLEEDQ--EDEVTGTSELTLSDTMLSMETVVAPGDGRD-REEEEEPLTEQTEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGPTRQQFTVSSDDTPPLN-AGNIYQ------KRPVLGDIVSGPVLSCLLHIAYLYGEPVLTYQYLPYISYLVAPGSNSNPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRIS-HEVLLPVLGFLTSFVTGFPSGAQARTVLCVKTISLIALICLRIGQEMVQQHLSEPVAT-FFQVFSHLHELRQQDLPLDPKGCTEGQLPEATFSDGQRRPVDPTLLEELQKVFTLEMAYTIYVPFSCLLGD-IIRKIIPNHELVGELAGLYLESMSPSS-------RNPASMEPTMASAGPEWD----PQSGSCLQDDG-----HSGTFGSVLVGNRIQIP-DSQPQSP------------GPLGS-----------LSGVGSSGGLSNR-------NEDNALKRELPRSAHGLSGNWLAYWQYEIGVSQQD-AHFHFHQIRLQSFPGHTGAVKCVAALSSEDFFLSGSKDRTVRLWPLYNYGDGTNETASRLIYAQHRKSVFYVGQLEAPQYVVSCDGAVHVWDPFTGKTLRTVDPSDSRVPLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGG-LNPGLVRSLAVSPSGRSVVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLISSSSDHSLTVWKELEQKPTHHYKSASDPIHTFDLYGSEVVTGTVANKIGVCSLLEPPS--QATTKLSSENFRGTLTSLALLPTKRHLLLGSDNGIIRLLA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q562E7-1", "uniprot_id": "WDR81_HUMAN", "id": "Q562E7-1", "name": "WD repeat-containing protein 81", "aln": "MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPARWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLS--YPLGGGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDS--------------VRQALQRVYGCSFLPVGETTQCPSYAREGP----------CPPRGSP-ACPSLLRAEALLES--PEMLYVVHPYVQFSLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELRLDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQP-------------TGQEELRSLVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHG-RFRDLRKSKFRLNKGDKQLDFTYEMTRQAFVAG-------------------GAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASMERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAPEPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEAS-WTRDRPVAGEDDLEQATEALDS------------ISLAGKAGDQLG--------SSS-QASPGLLSFSVA----SASRPGRRNKAAGAD----PGEGEEGRILLPEGFNPMQALEELEKTGNFLAKGLGGLLEVPE---------QPRVQPAVPLQCLLHRDMQALGVLLAEMVFATRVRTLQP----DAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSG---PEVPMGAERGKLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQAR---------------------RVEDEAQGRELVFALWQQLGAVLK-DITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANKYLLKPLIGAYESP---------------------------CQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQEES----------KDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSG-------LGLPDYTSGVSFHDQADLPETEDFQAGLYVTESPQ-----------------PQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSGDSSQDLKQSEGSEEE-EEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGGD-GEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGPTRQQFTVSSGESPPLS-AGNIYQ------KRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYISYLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRIS-HEVLLPVLSFLTSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVAT-FFQVFSQLHELRQQDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGD-IIRKIIPNHELVGELAALYLESISPSS-------RNPASVEPTMPGTGPEWD----PHGGGCPQDDG-----HSGTFGSVLVGNRIQIPNDSRPENP------------GPLGP-----------ISGVGG-GGLGSG-------SDDNALKQELPRSVHGLSGNWLAYWQYEIGVSQQD-AHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGG-LNPGLVRALAISPSGRSVVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQKPTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPS--QATTKLSSENFRGTLTSLALLPTKRHLLLGSDNGVIRLLA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FEV0-1", "uniprot_id": "WDR81_DANRE", "id": "E7FEV0-1", "name": "WD repeat-containing protein 81", "aln": "--------------------------MEWLAPALERDLGIDQRQTAHSQRPNELVVLVPTRWVMALRNKR--VTRCAKYESFSEGEICTLLQRSQMKLPSGWTRVCIQGLRKRKLG--YRFARETGCHGEGLSQDSFMTLMQGVSQSNFRNLWHEAYMTHVQPYADSVEQTPVLALDA--------------VRQALQKLFCSNFISTDRVSPSLSPAKEKEKDCPFLSTCSAPKQSTESLCPNVLPAECLLES--EEVLYVVFPYTQYTVHDIVTYSPAKLANSNAKILFILYQLLIAMRECHASGLLCGELSLLDIAVDEQLCSRLKISLAHYEKFKEYRDAVPYALQNKVPMSVSTKDNHNNGVSGQ--------LCRNCQDELKSLVLDWVNGQVSNFQYLMELNRLAGRREGDPNYHPVLPWVVDFTVPYG-RFRDLKKSKFRLNKGDKQLDFTYEMTKEALAAVSGSGGSNYPPDLGGPVVPGGPGQSDHLHVPHHISDVLSDITYYVYKARQTPKSVLCSHVRSQWEPNEYPASMERIQSWTPDECIPEFYRDPSIFRSIHPDMPDLDVPPWCNSYEEFIAVHRQLLESREVSQQLHHWIDLTFGYKLSGKEAIKAKNVCLHLVDNHTHLTSYGVVQLFDHPHPPRLALYQYAPPEPPHFGRVNVTTWQIPPLETTMD--------GVDGLVPEATGCESSGWS---VVGRDEELEQAIEALDLSGSSSSTSASVSIPVVGSAAGKTSGETIGLVVSPSHGSFPGEATGNVTNTLGSGIRTAMLHRAASVSKKPEASNLEDFKISLPDGFKPLQPLEELEKLNTFLVKGLHSEIEHTMDLGINKKDLRSVPKVPLSFTDLFQRDMQALGVLIAEIFYSSKLRGLRP----ETHLRDRFQAVLKLCSTNLRDVPLPLHHALDTLLQVHKHCLKTETIIMHPQGLPFLFKYDPICEGLPPPNPWQLLSPIVSPLPFPEYFPTLHKFIFSYHSKM--------------------ESINNIQGRDIVFNLWQQLETLLKGDITTEGLEILLPFVLSLMSEESTAVYAAWYLFEPVSRVLGPRNASKYLIKPLVGVYENP---------------------------RCLRGRFYLYTDCFVLQLIVRLGLQVFLSSLLPHVLQVMTGFESCNTAAGTEWEGMKVLRGAAGALDEEEEEYECDDRRSSNATSSGKVGGGSGGGSGGVGVVGDQGLVDYSSGISLNDQVFLNEGEDFQNGFYVNNSASGATTVGTKQQNQSTANKDQDQESLSVGKLSDKSSASEVSIGDRASLKSADSSQDLKQASDGEDGGELEDEEETVEDREITVQRVPSLEMTLSVCTEESEATVATLEGDVMNGIVQEDGEKNME-EEETEHDPLEDSEEKEHKILLDTVCKTVRWLSAKLGPTLTSRFIARNLLRLLTSCYIGLDKHQFMLSVNEENSLECVGSVYE------KKPVVGDQTARPVLECLIYIAHLYGEPVLTYQYLPYIGYLVSPPSS---CRLNTRKEAGLLGAVVLTQKIIVFLSDTTLMDMLMKIN-QEVLLPLLDLLTSTKMGFPSGVQTRSAVCLKTLSLMALICLRIGREMVQQHMAETLSR-FFQVFSLLQFLQNQIGSAPRREVAECTYLDLRIPDGAELTIELGVLEELQAVFNPEMAYASYIPFYCLIGDSGIRKLVTNHELVWSLAQSYHERASPGSPESNPVGGQRASAVGLSPSMGRQMSRSPFPAPSSTSTPLGGDILPESGTFGSHLVGNRIQVTRDTEACGSPNLSSLETWTHGRPYGSNAPPMSLATTALSSAGPSFSHSSYSWVMGPTPEDSALKQDLPRSSRSLQGNWLAYWQYEIGLNQQD-SHFHFHQIRLQSFIGHSGTAKCLAPLAGEDYFLSGSKDKTVRLWPLYNHGDGTREVEPRLTYTEHRKSIFYVGQLEALQEVVSCDGTVHLWDQFTGKNIRCNEPLDGKNPITAVTTMPAPHCSVVFASADSVLRFIDPRKPGLQHEFRLAYSNLSAGLIRCLAVSPGGRTIAAGFSTGFIVLLDARTGLVLRGWPGHEGDILQMKAAEGNLLVSSSSDHTLTVWKDVEHKPLHQYRTPSDPIHAFDLYGAEIVAGTVANKIGVYSILDSTASLAGSTKLSTENFRGTLTSLSVLPTKRLLLLGSDNGAIRLLA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKD0-1", "uniprot_id": "Q9VKD0_DROME", "id": "Q9VKD0-1", "name": "", "aln": "---------------------------MGDSEQIWPEIGVDPQHVCEAGGDGRFQVICDKAWLQSLERNR-------RLTHFPSWPLLDRRSYPIGQLEHPWTRILVQTYRKQPQSRVYPLPRISGDAPSSELPLSYSQAVSFVAHSNFKQLWEEAYRKYNGAHVRMCRSTPSAPSTKPPSGQGQLQPHDVVLKELIQRVYRCPVLHCQLDRDGVSDSSNAT------------SCSAGSCHANVLPALVAIETSTHISVFFYPPALECSLYDCITFSPALLGKNYNKTLFVIYQILQLAKHLQGQGLFLGDLRLQDIVLRENLWLQVLPRLQCNLLDDDPAGEDMSPLTPLVSEDLGEAREAQQALPSSSTMFDLRFAYDPAHFNLREYTEMWCNGQLSNFDYLTILNNACGRSLTNAAYHHIMPWVTDFSGRGGGAWRDLTKSKYRLNKGDVHLDLMYAHASQHGSAD-------------------GSYQAIGDQAPHHVSDFLSEITYFVYMARRTPQSILCAHVRPIWVPAEYPVSIQRLQEWTPDECIPEFYSDPMIFKSIHEDLPDLELPAWATCPEDFICKHREALESQYVSERLHHWIDLNFGYKLSGKAAVKSKNVCLTLVDQHRNLSQRGIVQLFASAHPPRRYATPWFSRTAPRLSQLYASPAKRLAKS--------------TENLQAESATGSSHLSLRLGDDGSSGSVHSSSASAS---------------ASNFYAITN------FIELPENYNPALLLHNLETLEAFYARTFPQQRASANP----EEKMISSDLMFEQNSAEHSFTNQLFASGDELPPKSKNLLREKR------------NCLQHLLNVRKERDLHVLGCLIIELFAMQRLRPLLMGNGLTATFDSRLSACRTVAQLHRQELPKPVRRVVRLLLQLEQ---PGEEDQGLPQPPNPAQLLEPMFSNLLLPFPSHYMAVYALVRSLHAFEANAVLLELQTHFSCKGGRECERYTEMDRQRVLFERKIAECKVMSCCAHVKRLLEPMSFAYEQFTPVELLLPHIIDLLRDERTSILTAWNLFDPIAQALGVSQTQQHLLQPLLKLYDVESVSSPDDGGSNGSTNSGGHLRFSASSSFKSRKSVKLYHHSFLLRLIVRFGLRCFLHHFIAPLIEAVGGYKEPEQGN--------------GYHYHSGGSRRTSKNLNFASENEVHQTEVAPEMKP--------DIEELFTFEDDHDRASTQDSKSIDSFDMRPSTSAAS------------AEEARESDGSPDKLVINELIYGARISPDKLSLKESQTPPALVPPPIGPRSPTIEIPMGPTAGGIRRSFQLSAIDCDIGSRKSVDSFDLISQAVEQLPPPAEESEAEASDSLQASVISRLSEAKAVQNNRISEMSAESLVWLSHRLGPVLTSRFITRNLLKLLSLCYVGQENLLPEVDDGGSSFNSSPDAANLNYFSIANARVVGDRSAARVLECLMSIAALYGENFLLLQYFPHISELISLCSK----RITGSLEGAIISSLQLLKYMVPCLTDASIMEHLQHIMLDAILLPILRLLSSTNLVMPSGYLGRSLLARKFLDAIYALSVRLGSDMTREHLCQPLLNPFFLIFNKAFGLPN---------DFACDLANLSLVGGASQPER--ALEELRDVFGPELAHTAYLTFLRFLGEANMKRTLSNLDFVLTLCHEHEQPN-----------GQSKIQLATNVSSGQDVD----SVDASCELAAN--------SFGTQIVGNRLQVARNNVELID--------------------------------------------------MVAYKLDQMPKTRHLKGNWLAYWRNETTRNEKDTQTLNLKQIRLQSFVGHTNSVRAIYALDNENSFISASKDKTVKLWSLRSEGDGRKTSACQFTYTAHKKSINSLGFLESLRYVVSCDSGIHLWDPFIGRPLSVLDAP-RHSAVTVVKCLPSHSPLVIAGTAESTVKMVDARSCEYVNEWRVCNASLPNATVRCLAVAPSGNWLAAGLSSGCIVQLDTRTGMVINSWRPMECDLLQLAAPSDQFLVSSALDHSLAVWHALDGIMHYQLKPPPEPAHFLQSVGPSLVYATTGNRVGVYADVAHSHAFSTITKLRSETFRGVLTSLAVLPLNRAFLAGNESGNIALLC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.:* :: . : .. .: *: :*. .* : : . : . . :* ***: :: **: . * : . : :. *: .*:::**..** .: .: :. . ::: :*::: . .: * : .: ..:* * :*: ::. * : :::* :*:*** * :. * **:::::* : .** * * * .*.: *:* .: * .: . . . . : :*: . * :*::*** ** **. .** :. ** ::***.**: * :*** ***:****** :**: * : : * *. . :.***:**.**:***:** **:**:*:**.***. * * ***.:::*:* *********** ** ** *** *:***::*.*... ::*: ** *** **. *******.*****.** *:* ***** *** * :*:. *:**** .** * . .* : :: . . : . : : :. : .. :: .* .. . . . *. . *. :*:. : . : : :. . ::* . * . :. : .**::.** *: *:. ::* * : : *:.* :. : :::* .:: .: ***: *: ..* * * : :: .: : . : : : . : : . : : * .: :*:***.::.*: :* *:: :** **:*:::.** :: ::*::**: *: : . ** ..*: :*:**:**: ** ::. :::.: * : : * .. . .. . . .: : : . :*:. : :.:: .:. :: :. . : :: . :. . ... :. * . :: . :: . : : . . : : .::: ::: : : .: : *** :***.::**.::****:**: **:* . :. . . . : *:** : **.**: ** **** .* **:*:*. *:: * *:. *..::.:: * : :: *:*:::*: * :* . :***:* :*:* :*** *: :. * :. : :.:*:* :*.::*:.:.: ** :*. * : : : .* . *:**: ** *:*:: *:.* ::*: ::: :.* ::* *. : : : . * : . . .. . :**: :****:*:. :. * * : . : *.*******: * .::* ::::******* **:.:.:.: .* .*: *:*.***:**:**.* . *** :: *: *:**: :* **: : *****. :*:** * *: : :. : .:*.* :*: : .:::*.::::* *. :*:*: . * . :*.**::*.*. :.**:*:* :* **:***:*:..* * *:**: * ....::**: **:*:**: :: :: :...:* * :: *..:* .*..*::** : : . *** :*.***.****::** :* :* *.:.* * **.", "identical_positions": 437, "similar_positions": 590, "identity": "19.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3404", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q92574-1", "uniprot_id": "TSC1_HUMAN", "id": "Q92574-1", "name": "Hamartin", "aln": "-MAQQANVGELLAMLDSPMLGVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPALHILTTLQEPHDKHLLDRINEYVGKAATRLSILSLLGHVIRLQPSWKHKLSQAPLLPSLLKCLKMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVAEVYLVHLHASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDHELDPRRWKRLETHDVVIECAKISLDPTEASYEDGYS-VSHQISARFPHRSADVTTSPYADTQNSYGCATSTPYSTSR------LMLLNMPGQLPQTLSSPSTRLITE--------PPQATLWSPSMVCGMTTPPTSPGNVP-----PDLSHPYSKVFGTTAGGKGTPLG-TPATSPPPAPLCHSDDYVHISLPQATVTPPRKEER-MDSARPCLHRQHHLLNDRGSEEPPGSKGSVTLSDLPGFLGDLAS-----EEDSIEKDKEEAAISRELSEITTAEAEPVVPRGGFDSPFYR--DSLPGSQRK------THSAASSSQGASVNPEP---LHSSLDKLGPDTPKQAFTPIDLPCGSADESPAGDRECQTSLETSIFTPSPCKIPPPTRVGFGSGQPPPYDHLFEVALPKTAHHFVIRKTEELLKKAK---------GNTEED----GVPSTSPMEVLDRLIQQGADAHSKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQRDTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCNDGCSDSMVG-HNEEASGHNGETKTPRPSSARGSSGSRGGGGSSSSSSELSTPEKPPHQRAGPFSSRWETTMGEA----SASIPTTVGSLPSSKSFLGMKARELFRNKSESQCDEDGMTSS----LSESLKTEL-----------------------GKDLGVEAKIPLNLDGPHPSPPTPDSVGQLHIMDYNETHHEHS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9EP53-1", "uniprot_id": "TSC1_MOUSE", "id": "Q9EP53-1", "name": "Hamartin", "aln": "-MAQLANIGELLSMLDSSTLGVRDDVTAIFKESLNSERGPMLVNTLVDYYLETNSQPVLHILTTLQEPHDKHLLDKINEYVGKAATRLSILSLLGHVVRLQPSWKHKLSQAPLLPSLLKCLKMDTDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVTEVYLVHLHASVYALFHRLYGMYPCNFVSFLRSHYSMKENVETFEEVVKPMMEHVRIHPELVTGSKDHELDPRRWKTLETHDVVIECAKISLDPTEASYEDGYS-VSHQLSACFPYRSADVTTSPYVDTQNSYGGSTSTPSSSSR------LMLFSPPGQLPQSLSSPSTRLLPE--------PLQASLWSPSAVCGMTTPPTSPGNVP-----ADLSHPYSKAFGTTAGGKGTPSG-TPATSPPPAPPCPQDDCVHGSAAQASATAPRKEER-ADSSRPYLHRQS---NDRGLEDPPGSKGSVTLRNLPDFLGDLAS-----EEDSIEKDKEEAAISKELSEITTAEADPVVPRGGFDSPFYR--DSLSGSQRK------THSAASGTQGSSVNPEP---LHSSLDKHGPDTPKQAFTPIDPPSGSADVSPAGDRDRQTSLETSILTPSPCKIPPQRGVSFGSGQLPPYDHLFEVALPKTACHFVSKKTEELLKKVK---------GNPEED----CVPSTSPMEVLDRLIEQGAGAHSKELSRLSLPSKSVDWTHFGGSPPSDELRTLRDQLLLLHNQLLYERFKRQQHALRNRRLLRKVIRAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYSQLQEQRDTMVTQLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRVELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQSKHPDTTKEVEMMKTAYRKELEKNRSHLLQQNQRLDASQRRVLELESLLAKKDHLLLEQKKYLEDVKSQASGQLLAAESRYEAQRKITRVLELEILDLYGRLEKDGRLRKLEEDRAEAAEAAEERLDCCSDGCTDSLVG-HNEEASGHNGETRTSRPGGTRASCGGRVTGGSSSSSSELSTPEKPPSQR---FSSRWEPALGEP----SSSIPTTVGSLPSSKSFLGMKARELFRNKSESQCDEDSVTMSSSS-LSETLKTEL-----------------------GKDSGTENKTSLSLDAPHPSSPNSDNVGQLHIMDYNETHPEHS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FEJ0-1", "uniprot_id": "E7FEJ0_DANRE", "id": "E7FEJ0-1", "name": "", "aln": "MSREQLNVGDLLPLLETSDLRQLNEIKGLINEHLNTDRGSVLLNGLVDYFLETNSAQTVHILSSVREPHDKHLFDKMNECMAKAPCRLPTLTLLGHVVRKQPSWIHKIAHYPLLLSLLKCLKTDTDVVVLITGVLVLITLLPMIPQAGKQHLYEFFDIFGRLASWNLRNPGHVPEVYLIHLHASVYSLFHRLYGMYPCNFVSYLRSHYSMKENMDTFEEVVKPMLEHVRIHPELVTGTKDQELDPSRWKRFEIHDIVIECAKVSLDPKEASCEEGYASMPEHFCAHLQQRPADCTASPYGDFHSSYGSSSSTHFSTPRQPVVPPLALSSISGTQPPYRSPTGTRRQNSSCEFNATYGVKDSLWSPSSQCGMATPPSSRGMSPNPELSQSASHLPSRLYSTPAGGKGTPSSSTPAAATP--PPSLSDEYPPVSTPRSTASPPCKDGRPLDHIKPVLVRQEQLRESEKTGPETMNHRDGRGENMPMTLTELSVYMKEQEQLRIEKEREDAAITEELLKLTEEKRDLAGLRG-FDSPFFSTTETLTGAQQKPLPSSILHNTISTPDKTEITPSDKGRVSRGPSQEQPWSFQPVFMPIEHPTHSLLHRSPSAPD-DEALKFGLCSPSPCKPPP-----------MPYEALFDMALPRAASLFVGRKTSEIVQRVAMERFQRGDSGRQGEDEGVEGVASASPLEVLDRLVQQGGDAHDKVLKRLPLPSKSADWTHFGGSAPLDELHTLRSQLLLLHNQLLYERYKREQHAVRNRRLLRRIINATALEEQNNAMKDQLNLQSVDILSLRESLQVEQQRYRQLWDDRETVVTRLHSQIRQLQQARDDYYTKNQELQSKLQECQKRIGEMEAELQKANNEVCHTGHLLNQLTAKLSSSESIQQQLSFLNKQLLLLGEAHKLCVQELHQAGPDTSKEVQMLQTSWGKETERLKQNLLLQSQKLDAAQQRVAELETQLSKKEHLIAEQKKFLEDVKAQAKGELQASESRYQAQRRVTLALQTELLQLYSRLETED---SSAADSALQAEGVTEP--CITTEPSVIVVGGAIKTATKEDGKPHQSPRGYGSTLSPGHPKASSSPDNSVNGNRDTPPPVLVEPPPHRPHSPLGPPGPLVSSDTPLTVGSYPSAKSFLGMRARELFRNKSESQCDEEETPPPRLTGLSQGLKTELCTETTAKRPSVSTTAQSVTLITSGKESQPDAQRAKKQDTLGSRCPERPRQQPLRIMDYNESRHEHS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:*:**.:*::. * :::..:::* **::**.:*:* ****:***.* .:***::::*******:*::** :.**. **. *:*****:* **** **::: *** ******* ******* ********:******:***** :********:** *::****.****:*******:***************:**********::*********:************:**:**** *** :* **:******:****.*** *:**: :..::.* : *.** *:*** * :.*** ::** *:.* * * . .* * *...** . : :***** ***:***:* * * . ** *: :.*.******* . ***::.* * . .*: * .:::.:.* *: * * :* * ** :.. . .: . ::* * :*: *: ***::*:***:.** ::* : : . ** *****: ::*.*:*:* *.: * .: :.:.*. : . .: * : : .* **: * * ... : : :*: .: :***** ** **: **::***::* ** :**.*::::. *. ** *.*:**:******::**..**.* *.:*.*****.********.* **::***.*************:**:***:*******::*.*:****:* ******:**. ** : *** ** ** ** ::*:*:**:*********: *:::*.:.****:**::*:: *.*:. **:****:**** **.*:: ***.***:***:.***:***:***.::* :::*:. .**:***:*::::: ** *: :.::* *.*:**::*:*: ***: *:**:**: ****:***** ** *:* *:****:**:::* .:: *:*:**.***.:. . : * **.. * * . : :** : *: .:*:.: . . . .: ..**...* .. :.** . * ...:* . *:. * **** **:******:***************: . . **: ***** **: : : . . * . * *:******:: ***", "identical_positions": 570, "similar_positions": 332, "identity": "45.67%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3406", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AHX2-1", "uniprot_id": "A0A8I6AHX2_RAT", "id": "A0A8I6AHX2-1", "name": "Telomere-associated protein RIF1", "aln": "-MTAP--GRSPLEPLLETWEDPSVSPGEQTDAYLTLTSRMTGEEGKEVIAEIEKNLPRLYTVLKAHICSQSSELSSAALQALGFCLYNPRITSGLSETNIQELLLTLN-GIIKSSDKNVCTRALWVISKQTFPTELVSKMVSSIIDSLEVILSKGEIHSAVVDFEALNFVCHWFLRCRLIEQAPVQMGEESVRWAKLVIPLVVHSAQKVHLRGATALEMGMPLLLQKQQEIALITEHLMTTKLISELQKLFMSKNETYVLKLWPLFVKLLGKTLHRSGSFINSLLQLEELGFRSGTPMIKKIAFIAWKSLIDNFALNPDILCSAKRLKLLMQPLSSIHVRTETLALTKLEVWWYLLMRLGPQLPANFEQVCVPLIQSTISVDSSASPQGSSSRG-STPGLSPLTPGNKGAS-----YGTPRVNLGSNIGGMATIPSIQLLGLEMMLHFLLGPEVLSFAKQHKIVLSLEPLEHP-LISSPSFFSKYAHTLITAVHDSFVAVGKDASDAVVSAIWKELISLVKSVTESGNRKERSGSEVLTLLLKSLENIVKSEVFPVSKTLVLMEITVKGLPQKVLGSPAYQVANMDILNGTPALFLIQLILNNNLLECGVEDEKFFLNLETLVGCVLSGPTSPLAFSDSVLTVINQNAKQLANKEHLWRMWSMIVSPLTDVIHQTNEVNQGDALEHNFSAIYGALTLPINHIFSTPTFPTGTMKTLLKTWSELYRAFARCAAVVATAEENLCCEELSSKIMCSLEDEALSDLLFLDRISHVVVVMVDCIDFSPYNIKYQPKIKSPQRSSDWSRKKKEPLGKLASLFKLIVRIIDSFHTLSLKETYSDTLLAIGNSIISMLSNIFGHISLSSMIREIFTTFTRPLALLYEN-SKLDEVPKVYTSLNNKLEKLLGEIVACLQFNYLGAYDSELLGQLSPLLCIIFLHKNKQIRKQSAVLWNATFAKATALIYPEELKPILRQAKQKILLLLPGLENVEMMDESSGPYSDATENSQLNVKISGMERKSSGKRDSILAHTKEKKEN----VRLSAKLKLDSSSPKLKNGKLLEEEKSTDFVFIPPEGKETKARILTEHQKEVLKTKRCDIPALYNNLDASQDTLFSAQFSQEESMESLTLTEKPKEDAKIIK-EEQMESAIFIPQDAPENCTIDQHPEKASLPN-YGGSVAETNPETLSTGFDARKEMLISSKMS-AECSSSSE-TTVVSSSSVSNATFSGTP-QPTSRRQTFITLEKFD-GSETRPFSPSPLSNLSSTVTVRNNQDNTTKTDMPQKARKREVTHSKSDSEKLANGGKKSSRRWSKAEQSVNKKFKPSPTSEQEEQSFE---------NNPPDLLSSAECVSENHDHPSEATLEHEDRDPRASVEN--ASLEDLAEG-KNVGINKDPKES----ASPVVAATEQTVNEGSQAAAAAPNPKALRRSSRRRSEAVESSGDSQEKESGQQKRERRKEEERTISKSPCHIKDDKLPKQKLTAEPPIQENLTEKENSLQERTLGEPSANAEIDQNRRKPDLETVSSEGGGGTLDNVDKSSEKPLRGRTRYQTRRASQGLISGVENSESDSSEAKEEVSRKKRSGKWKNKSSDSVDIEEQEEKMVEDEVMKTASQTHDGQAVPD-DINAVAQICEKNINN-RVILQDSSGSTDSLQVSLTG----EDKSKTSKCLDSSLVSLPVPESNLRTRNASKR-LYKRD--------TDSNVGASDMSMSPEKCTQVVECQHKRSRRVRRSKSCDCCGEKSQSQEKS-FTGLKNTESSAMKSLETK-KTDLQMPETAPETQEANEHVETKSVGKQPVVNFHLGL-EEISATGD-LIKSEPKLEEDSKNS-PPSEPVNMKEKTYGTDASEAVSEIQEPCGEEYNAPEDPCLSDCKDISQKYPLDNKAESPEAILQKELDISNV---GKACKVMDGSSPEGVESIESSVRKDTFGAAVSEKSTQMDVSVDVATEEDNKKDECEAVTTEVNAEGVATEDFNSSMGLSDTTTPVSKDVQAEH---PASGELEAGSNESDSGSCEEMNKEMESYKAQMNTEIDNAR-----VKDMDMIASTSKSEEALIGRLDVNTEGFVSD-IEMSSGEGTGKC-KTETNIELNKLDEI-KLGGNQTTVGNETLQEVCFTSEKVEELPQPLIP-EVTSELGAESNNVSPVKL-ELDPSFGSASESPSGVQ-ARCVWSPLASPSTSILKRALKRSQEDEIS-PINKVRRVSFADPIYQAGLADDIDRRCSVVRSHSSNSSPVIKSVKTSPT-SHSKHNTTSAKGFLSPGSQSSKFKSSKKCLITEMAQESMLSPTESVYPALVNCAASVDIILPQITSNMWARGLGQLIRAKNIKTIGDLSTLTASEIKTLPIRSPKVFNVKKALRVYHEQQMKSRGLEEIPIFDISEKAVNGVESKTLST--DEERFAS------------------DLIDPVTLDTPLSKNLVAQISALALQLDSEDLYSYSGSQLFEMHEKLGTMANSIIRNLQSRWRSTAHENS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PR54-1", "uniprot_id": "RIF1_MOUSE", "id": "Q6PR54-1", "name": "Telomere-associated protein RIF1", "aln": "-MTAP--GRSPLEPLLETWEDPSVPPGEQTDAYLTLTSRMTGEEGKEVIAEIEKNLSRLYTVLKAHISSQNSELSSAALQALGFCLYNPRITSGLSEANIQELLLTLN-GIIKSSDKNVCTRALWVISKQTFPAELVSKMVSSIIDSLEVILSKGEIHSAVVDFEALN------VIIRLIEQAPVQMGEESVRWAKLVIPLVVHSAQKVHLRGATALEMGMPLLLQKQQEIALITEHLMTTKLISELQKLFKNKNETYVLKLWPLFVKLLGKTLHRSGSFINSLLQLEELGFRSGTPMIKKIAFIAWKSLIDNFALNPDILCSAKRLKLLMQPLSSIHVRTETLALTKLEVWWYLLMRLGPQLPANFEQVCVPLIQSTISVDSIPSPQGNSSRGSASPGLSPLTPGHKGASP----YGSPRGNLSSNTGGMAAIPSIQLLGLEMMLHFLLGPEVLSFAKQHKIVLSLEPLEHP-LISSPSFFSKYAHTLITAVHDSFVSVGKDASDAVVSAIWKELISLVKSVTEAGNRKEKSGSEVLTLLLKSLENIVKSEVFPVSKTLVLMEITVKGLPPKVLGSPAYQVANMDILNGTPALFLIQLIFNNNLLECGVEDEKFFLNLETLVGCVLSGPTSPLAFSDSVLTVINQNAKQLVNKEHLWRMWSMIVSPLTDVIHQTNEVNQGDALEHNFSAIYGALTLPINHIFSAQTFPTGTMKALLKTWSELYRAFTRCASLVATAEENLCCEELSSKIMCSLEDEVLSDLLFLDRISHIIIVMVDCIDFSPYNKKYQPKIKSPQRSSDWSRKKKEPLGKLASLFKLIVKVIDTFHTLSLKETFSDTLLAIGNSIISMLSNVFGHISLPSMIREIFATFTRPLALLYEN-SKLDEAPKVYTSLNNKLEKLLGEIVACLQFSYLGAYDSELLEHLSPLLCVIFLHKNKQIRKQSALLWNATFAKATALVYPEELKPILRQAKQKILLLLPGLENVEMMDESSEPYSESTENSQLNVKISGMERKSSGKRDSILAHTKDKKKK----VKLSAKLKLESSSPKIKSGKLLEEEKSTDFVFIPPEGKETKARVLTEHQKEVLKTKRCDIPALYNNLDASQDTLFSAQFSQEESMESLTLTEKPKEDAKIIK-EEQMESTIFIHQDAPENCGIDEHSENASLPN-CGGSVAETNPETLITGFDARKEVLISSKILSAESSSSTE-TSVVSSSSVSNATFSGTPPQPTSRRQTFITLEKFD-GSETRPFSPSPLNNISSTVTVRNNQDNTTNTDMPPKARKREVTNSKSDSENLANAGKKSSRRWSKAEQSVTKKSKPSLTSEQEEHSSE---------NNSPDLLSPTEHVSENDDHPSEATLEHKDGDPKPAVEN--ASLEDLTTEEKNVGINMESKES----TASVVARTEQIVNEDSQAAALAPNPKTLRRSSRRRSEAVDSCSDSQERESGQQKKERRKEEEKIISKSPLRIKDDKLPTQKLTDESPIQENLTEKGNTLPERTSGEPSVNAEIDQNRRKPDLENVSSEGGGGTLDNLDKSSEKPLRGRTRYQTRRASQGLISAVENSESDSSEAKEEVSRKKRSGKWKNRSSDSVDIEEQEEKKAEEEVMKTANQTLDGQAVPDVDVNAAAQVCEKSTNNNRVILQDSAGPADSLQAPPKG----EEKSKINKCVDSSFVSLPVPESNLRTRNASKRLLYKQD--------NDSNVRVSDSSLSPEKFTQ-VECQHKRSRRVRRSKSCDCCGEKSQSQEKS-FIGLKNTESYAIKSVEKK-KTDLQVPETAPETREARDHAETKLAGEEPLVNFHVGLKEENCTTGD-SVKSEAELQEAS----LPPEIVTVKEKTYDTDASEAVSEIQGPCSENHSPAEDPGLSECKDISQKQLSEN----------GELDISDV---GKACKVIAGSSPEGVETMELNVRNDAFVAADSEKSTQMDVSVDVATEEDNKKDECEAVTTEVNVEGVATEDFNSGMDLSDTPIPVSKDVETEH---AASGEIEGESNESDSGSCEEMNKEMGSHKAQMSTEIDSAR-----VKETDILASASKSEEALIGRLDVNTQSFVSD-IEMSSGERTVNC-KTETSIELNKLDEA-KLSGNEATVGNDTLQEVCFTSEKVEKLPQCLLV-QVASELGAESNTTSPEKL-ELD-SFGSVNESPSGMQQARCVWSPLASPSTSILKRGLKRSQEDEIS-PVNKIRRVSFADPIYQAGLADDIDRRCSVVRSHSSNSSPIIKSVKTSPT-SHSKHNTTSAKGFLSPGSQSSKFKSPKKCLITEMAQESMLSPTESVYPALVNCAASVDIILPQITSNMWARGLGQLIRAKNIKTIGDLSTLTASEIKTLPIRSPKVFNVKKALRVYHEQQMKSRGLEEIPIFDISEKAVNGVESRTVST--DEERFAS------------------DLIEPVTLDTPLSKNLVAQISALALQLDSEDLYSYTGSQLFEMHEKLGTMANSIIRNLQSRWRSPAHENS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5UIP0-1", "uniprot_id": "RIF1_HUMAN", "id": "Q5UIP0-1", "name": "Telomere-associated protein RIF1", "aln": "-MTAR--GQSPLAPLLETLEDPSASHGGQTDAYLTLTSRMTGEEGKEVITEIEKKLPRLYKVLKTHISSQNSELSSAALQALGFCLYNPKITSELSEANALELLSKLN-DTIKNSDKNVRTRALWVISKQTFPSEVVGKMVSSIIDSLEILFNKGETHSAVVDFEALN------VIVRLIEQAPIQMGEEAVRWAKLVIPLVVHSAQKVHLRGATALEMGMPLLLQKQQEIASITEQLMTTKLISELQKLFMSKNETYVLKLWPLFVKLLGRTLHRSGSFINSLLQLEELGFRSGAPMIKKIAFIAWKSLIDNFALNPDILCSAKRLKLLMQPLSSIHVRTETLALTKLEVWWYLLMRLGPHLPANFEQVCVPLIQSTISIDSNASPQGNSCHVATSPGLNPMTPVHKGASSPYGAPGTPRMNLSSNLGGMATIPSIQLLGLEMLLHFLLGPEALSFAKQNKLVLSLEPLEHP-LISSPSFFSKHANTLITAVHDSFVAVGKDAPDVVVSAIWKELISLVKSVTESGNKKEKPGSEVLTLLLKSLESIVKSEVFPVSKTLVLMEITIKGLPQKVLGSPAYQVANMDILNGTPALFLIQLIFNN-FLECGVSDERFFLSLESLVGCVLSGPTSPLAFSDSVLNVINQNAKQLENKEHLWKMWSVIVTPLTELINQTNEVNQGDALEHNFSAIYGALTLPVNHIFSEQRFPVATMKTLLRTWSELYRAFARCAALVATAEENLCCEELSSKIMSSLEDEGFSNLLFVDRIIYIITVMVDCIDFSPYNIKYQPKVKSPQRPSDWSKKKNEPLGKLTSLFKLIVKVIYSFHTLSFKEAHSDTLFTIGNSITGIISSVLGHISLPSMIRKIFATLTRPLALFYEN-SKLDEVPKVYSCLNNKLEKLLGEIIACLQFSYTGTYDSELLEQLSPLLCIIFLHKNKQIRKQSAQFWNATFAKVMMLVYPEELKPVLTQAKQKFLLLLPGLETVEMMEESSGPYSDGTENSQLNVKISGMERKSNGKRDSFLAQTKNKKEN----MKPAAKLKLESSSLKVKGEILLEEEKSTDFVFIPPEGKDAKERILTDHQKEVLKTKRCDIPAMYNNLDVSQDTLFT-QYSQEEPMEIPTLTRKPKEDSKMMITEEQMDSDIVIPQDVTEDCGMAEHLEKSSLSNNECGSLDKTSPEMSNSNNDERKKALISSRKTSTECASSTENSFVVSSSSVSNTTVAGTPPYPTSRRQTFITLEKFD-GSENRPFSPSPLNNISSTVTVKNNQETMIKTDFLPKAKQREGTFSKSDSEKIVNGTKRSSRRAGKAEQTGNKRSKPLMRSEPEKNTEESVEGIVVLENNPPGLLNQTECVSDNQVHLSESTMEHDNTKLKAATVENAVLLETNTVEEKNVEINLESKEN----TPPVVISADQMVNEDSQ-VQITPNQKTLRRSSRRRSEVVESTTESQDKENSHQKKERRKEEEKPLQKSPLHIKDDVLPKQKLIAEQTLQENLIEKGSNLHEKTLGETSANAETEQNKKKADPENIKSEGDG-TQDIVDKSSEKLVRGRTRYQTRRASQGLLSSIENSESDSSEAKEEGSRKKRSGKWKNKSNESVDIQDQEEKVVKQECIKAENQSHDYKATSEEDVSIKSPICEKQDESNTVICQDSTVTSDLLQVPDDLPNVCEEKNETSKYAEYSFTSLPVPESNLRTRNAIKR-LHKRDSFDNCSLGESSKIGISDISSLSEKTFQTLECQHKRSRRVRRSKGCDCCGEKSQPQEKS-LIGLKNTENNDVEISETK-KADVQAPVSPSETSQANPYSEGQFLDEHHSVNFHLGLKEDNDTINDSLIVSETKSKENTMQESLPSGIVNFREEICDMDSSEAMSLESQESPNENFKTVGPCLGDSKNVSQE-SLETKEEKPEETPKMELSLENVTVEGNACKVTESN-LEKAKTMELNVGNEASFHG--QERTKTGISEEAAIEENKRNDDSEADTAKLNAKEVATEEFNSDISLSDNTTPVKLNAQTEISEQTAAGELDGGNDVSDLHSSEETNTKMKNNEEMMIGEAMAETGHDGETENEGITTKTSKPDEAETNMLTAEMDNFVCDTVEMSTEEGIIDANKTETNTEYSKSEE--KLDNNQMVMESDILQEDHHTSQKVEEPSQCLASGTAISELIIEDNNASPQKLRELDPSLVSANDSPSGMQ-TRCVWSPLASPSTSILKRGLKRSQEDEISSPVNKVRRVSFADPIYQAGLADDIDRRCSIVRSHSSNSSPIGKSVKTSPT-TQSKHNTTSAKGFLSPGSRSPKFKSSKKCLISEMAKESIPCPTESVYPPLVNCVAPVDIILPQITSNMWARGLGQLIRAKNIKTIGDLSTLTASEIKTLPIRSPKVSNVKKALRIYHEQQVKTRGLEEIPVFDISEKTVNGIENKSLSP--DEERLVS------------------DIIDPVALEIPLSKNLLAQISALALQLDSEDLHNYSGSQLFEMHEKLSCMANSVIKNLQSRWRSPSHENSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0UY57-1", "uniprot_id": "B0UY57_DANRE", "id": "B0UY57-1", "name": "", "aln": "MMAAVPLSSTSLLPLLECLEDESAGLSAQTDAYITIANRLNGEEGRQFLPVVVKHFARLSKVLLVHISSENEELCQAALQALGFCVFHSHIVSVIPANISENILSTLCNVVVKSKEKFTCTRALWVISKQNFPPEVASKMAPEILKSLEAMQTR-EVQSILIDHESLN------VIIRLLEQAPVPMAVGAVCWAKLVIPLVVHSANKVRLRAAAALELGMPLLLEKQQEVAAIVEPMMSSVLIPEMQKLFASKNETNMLKLWPLFVRLLGKLLHKGGAFINSLLYLEELGFRNSSPNIKKIAFIAWKSLIDNFALNPDILCSSKRLKLLMQPLSSIQVRTEALLLTKLEVWWYLAVKLGPNLSANFEQVGVPLLHSTLPSDSPLQSPTTPARTSNPSNGTPNTP-KSGIPSCSTPSTTPRMNLNSSMQAPQSYRSIQLLGLEMLLHWLVGPEVTVTAARENLQLSLEPLTHP-LFTSPSTFSRHASTLISASKEGIITVGKHAPEALLNLIWSNLIISVSAAIEAGNKKERQGSEVLTLFLQALQSILSSDALPPERALLLLEATVKGIPQKVLGSAAYQVANMDVLNGTPALFLILLFYKSNQLSSFLEDERFFSSLETLVSCGFCGPTSPLAFGEAVLGAVNGSVETVKNKKQLWRMWSMVVSPLTDTITQTNEVNQGDALEHNFSAIYSALMFPVIHLLPYSALPQTTQKAMISTWSRLYKAFARCSALVATAEENTCCEELCVKISASLDREALKSLSMLDAIAHILLIIVESMDFSPYTPQFQQKMKSPRTPMSWVRKRSRALGNLSTFHTLLIQTLEAFLTADHSEESAEPLNGIGSALVSILTSLFTNITLPSFLQEVLSSLTKPLARLYEQFSCCDDPSKLSPELGHKLEKLAADLLGCLQT-HLTLHDDEFLTVLSPLLCVLFLHKSKQVCSVVTQFWNATFGNALTLSYPEPLKCVLNQAKQKTPLILPGFEVVDVPDDYSGTYMS--ESSQLEPQISGVKVTSVGKRDSLLARAEELTGKSSVTTSKPVSVKLDFGSPKPLRREALEEEASEDFVFIPP---EMKERVLTEHQKEVKRTKRVDIPALYNNLDASMDTTVFSQYTQSQEESMDTLPKGEKDHP------VEAASVQLREVASNEVPTTDVKVQKVTSSDIETPDKATPNKDQ-TLEMDQSPSTGVSVDVSGLEKSALEGTSPNISSS---SDVVSGTPPKPNSRRQSFITLEKYAEGKSTSPASP----AFTGTLTRRSRR---------LEASQASTSNQNDSQPQIKKVDSQESQKMSSIDMSIQN--EHASMEVKDEKSVG---------ANPCEGTDEEDVVPDTQTQVSGDTLGIKSSPVSKAHAEAQGTPEKNSQSPNDSLASQEPRRSGRRRSKPVRPGQDAEEIKSKSQEQASQPADSAIINSQKPLLASPSSTLTGRRKKKVETNKMEDQLNNEEMKGDLSQSDSQISAADPPQTVGVHANKDLSQTELSPKSSPVTQSNSQSKERLPALCESESMSLGRQETKTQLEESTEKETNNDSQNASSAARP---KHIQSTTSDSESDSQQIVRKRRSRRSETKLLEISGVP------IKEDLNQTDSQTPTG---------VKGRAMRRRTVEGAESSKDSTSAVNTEELSAGK----ESSQELGRYRTRRSRGLLSPES-MESENSDSR--------------EDGARPKKRLRKPPSTEVLPVASEPKVIEMVPEKDDVQSEVLMETSKDEADPENISNTSVSETKELEQKNKEEVPAPCDAPHEQIITEKAAS-----NNKIDTDLTDTDEKETVKAEGEEANESSQTGS-------------EDFKKTDVLHKCPHTKGRGRARRRSKNCNCFSNNRDVFSQDSDFQES--------QDLKNEQVP---LAANILNSQPDQSSPSTASEENKSSAIEEVPVADVPSLSALSADLPSEVSPSESPITKLGVIVSQLPEVEKEAQPGSSKPMKDSSKELVEEVN------RLSSGSTGGQKHKGENRLENTSVSQEPVQSSTPQDT-----SPSQGRPVDDAPICQEQLESSHVQQEDAVNP-AVMEREDLAVSEQRQEKAVLSEELDGKGLLDKETTLVEKEEEMQVNNQDLPVDVQEELPVVSQSSTSEACLDSPPKPKLLSALSGELEPG-QSPTRSR--SRVWSPSASPSTSILKKGQKRACEEETPSPIPKSRRVSFATPIYQQELADDIDRRSPVIRTSSPRSKVLSGQSKYITTPTKGGYTSLSPRNLRSPGS-----KSSKKCLISEMSQEPRPIPKDCVYPALVGCSTPVEAVLPQISSNMWPRGFGQLVRARNIKTVGDLSALTPNEIKSLPIRSPKLSNVRKALKTYHEQQRKGR-SDDLKSFDEMEKMTSEPEEMELPQNQDEEQTSGPEAQTAESETQEDKASEVEVNSEVVTEENQSHDLLSDIVALGERFTPEELSQHSASQLGLMHEHLSGMMRSIVTNLQSRLLSNLDDSLP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XZ34-1", "uniprot_id": "RIF1_DROME", "id": "Q9XZ34-1", "name": "Telomere-associated protein RIF1", "aln": "-----------------------------------MDVDFGAQAGQSYRTVQLSAKEVLAAGRRQHYCNMIDLLASS-------CKSSGLIATSFTDDELVEFWLGDILPLMFDADRKIQDCAVAALAEALVALDVS----------------------------------------------------------------VIHSAKCWPQIRSEFVDKYTIIIGEMR------------------------DAKNSNWHKIWTLLVQIMDEDLLRGCVYINKFLALVELGFRNPDNGVRSEAFLCWRVLIKIFAAY-DELTSAKRLRLLLIPLRTSQSRSSHVSGIKLRVWWYLLSCLDHELPKSFDSAVEHFLAFMLG-------------------------------------GGPRNLATGLAHNYQTARELALP----CLVALWGVESSEPLQRLMRELRLETLVQPSPLMSVEVFQQHWKPLLAAAVS------------------------------------------------GLKLLTENDATEAEQLLLQLLVRNLCLAMFRLAVAPFNVA------------------------CCSEIEKILQAEDNSGGRVVRALFNTIAADNLVMERVSG-------------------------------SDHLDVLEAYLKLVLKSKTEVPAAILQRSIACIFAVDRIEANNQNEFRMLGSFAELLMQANDEEDFEGFAFKLQVWR--------------------------------QVSQALSNYLRNNALEYRVAHNASLLDTWLLWPLQTLAAFAGRRASNSFDASFCDQWRQLVNAGQNAPGRKKFLTDLKATLTDLLK-----------------------SKDEPLFAELFDAYVTSLIKFGLCKEAPLYKDVFGLLQTIFEQPSSQKTLEACLNTLRNLVVELRQNELMVVFDSLKPTLSSGIQCWNKMKCEGGFLEEWKRG------------------------------------------IQEKFRKLPMKTMANQLKELFKADDLFVIIPSVWSLNPEKLTDRQKERFAEK-SDIPALYNDMSQSQDSASIKPWTP---------------------------KKVVIAKSKQGELALTGKDDNGEVIDITASEESEKEPVRVDVVTPIRKKPGR--------------------------------------------------------------------------------------KSQAQKELEAAARAASLAEEPPKRQTRTRAAQKETEQVAQPQPAFEPQLRSPK---------------------------------------------------------------------------KLPPSPVVQSTAAAVKQAKVAKPTPVVVIAQSEDLFPEVAAEPEPQPE--------------------PVKKPDPVPETTQLTPPDVPLEAVPSTQLPGSSGDPAASAGAVAAGEMSPKKSGTRIYNLSSPPDRKQTNNSSSPTLRPKPTGHLTGRGAQLINMIRNKKLDAASGSPYACMSTSR--------------------------------------------LVHQVTPARAQDRAEQVSTPTSELNELTG---------TDHTSTPIQAPPSKDLLVFSKRLPSPSASPS--------------------------------------VSILKRKLRCESLDDVTLDSPALKRK---------------------------------------------------------------------------------------------RVSFHDPPVSVTKEYLRDAEETRSSLKP--------------------------------------KRCLLMDKVAQTTEMRQALRRR----------GRLDSIIEIERFASEQTARTATTDKSLDKSTGEAPEEDAFTSLKWNDTGN-----------------------------------------------------------------AHNISISEEPVKAMEVESELETAG--------------------------------QDLAIMDPEAALDLAVAQLPLESVLQRYFDKSPLKSAGMLAKFLS-------------------------AQMTANEKLKTNVLETLSENHSKDFLDHAVRENLSSVVCDRLNPTSVLEYVCAKSKISASCRN------GLLAQVPEILKSGPRSDSER-------------------------------LAFVQQLMVQCSPGDDLLLDLIDLLMRTR------RERNNSTSTHISKGVVSAVGSPDNVAETAADSSSNL--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: *:. . . * * .. . *..: * *.: :. :: : . :: *: .::: .. :: *:***: : :: :: : : . ::: *:*.*:*:::.. * :. :**.:* * *****. ::. **:.*: **. ** * * *:***:**: ** : : *:. : **.***** *. .*. .*:.. :: : ** . : .: * * * * * : * **.* :* : * . *.:: .*::* . .*: : ..:. .: *: : :. *. ..::** . . *::: :. . . . ..:* .: *: :. :: *.** :. : : :: : . : . .. :: : : :: *::: * :. *: : . :.. : . . * : :: : :* .: .: : . . . .: : :: :: : : * * * .::. . : . :: :: .: . *: : : * :: . * . : : :. : . *: . * * : *:..* * . : . **::*** * ****:**::. * *: :: . . : :: : . . . :: . .: : : . : : : : : .: . : .. .*. : . . * . . . : . . ::*:. . . . :... *: . . . . . .: : . .* .. : : .: . . . .. : . . .. * . . . : . .: . . . : : .. . : .: : . : : : : . :: : .. . . :. . .*.:*: :. :: .: : .. : : : : :. : : . :. : * : * :* * . : :* * * .* * :* .* .:* . . : : : . : . * ", "identical_positions": 132, "similar_positions": 395, "identity": "5.22%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3421", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8WYQ5-1", "uniprot_id": "DGCR8_HUMAN", "id": "Q8WYQ5-1", "name": "Microprocessor complex subunit DGCR8", "aln": "METDESPSPLPCGPAGEAVMESRARPFQALPREQSPPPPLQTSSGAEVMDVGSGGDGQSELPAEDPFNFYGASLLSKGSFSKG-RLLIDPNCSGHSPRTARHAPAVRKFSPDLKLLKDVKISVSFTESCRSKDRKVLYTGAERDVRAECGLLLSPVSGDVHACPFGGSVG--DGVGIGGESADKKDEENELDQEKRVEYAVLDELEDFTDNLELDEEGAGGFTAKAIVQRDRVDEEALNFPYEDDFDNDVDALLEEGLCAPKKRR-TEEKYGGDSDHPSDGETSVQPMMTKIKTVLKSRGRPPTEPLPDGWIMTFHNSGVPVYLHRESRVVTWSRPYFLGTGSIRKHDPPLSSIPCLHYKKMKDNEEREQSSDLTPSGDVSPVKP------LSRSAELEFPLDEP------------DSMGADPGPPDEKDPLGAEAAPGALGQVKAKVEVCKDESVDLEEFRSYLEKRFDFEQVTVKKFRTWAERRQFNREMKRKQAESERPILPANQKLITLSVQDAPTKKEFVINPNGKSEVCILHEYMQRVLKVRPVYNFFECENPSEPFGASVTIDGVTYGSGTASSKKLAKNKAARATLEILIPDFVKQTSEEKPKDSEELEYFNHISIEDSRVYELTSKAGLLSPYQILHECLKRNHGMGDTSIKFEVVPGKNQKSEYVMACGKHTVRGWCKNKRVGKQLASQKILQLLHPHVKNWGSLLRMYGRESSKMVKQETSDKSVIELQQYAKKNKPNLHILSKLQEEMKRLAEEREETRKKPKMSIVASAQPGGEPLCTVDV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9EQM6-1", "uniprot_id": "DGCR8_MOUSE", "id": "Q9EQM6-1", "name": "Microprocessor complex subunit DGCR8", "aln": "METYESPSPLPREPAGEAMMENRACPFQVLPHEQSPPPPLQTSSDAEVMDVGSGGDGQSEPPADDPFNFYGASLLSKGSFSKG-RLLIDPNCSGHSPRTARHAPAVRKFSPDLKLLKDVKISVSFTESCRSKDRKVLYTGVERSTRPECGQLLSPVSGDVHACPFGGSVG--NGVGLGGESADKKDEENELDQEKRVEYAVLDELEDFTDNLELDEEGTGGFTAKAIVQRDRVDEEALNFSYEDDFDNDVDALLEEGLCAPKKRR-MEEKYGGDSDHPSDGETSVQPMMTKIKTVLKSRGRPPTEPLPDGWIMTFHNSGVPVYLHRESRVVTWSRPYFLGTGSIRKHDPPLSSIPCLHYKKMKDNEEREQNCDLAPSGEVSPVKP------LGRSAELDFPLEEP------------DSMGGDSGSMDEKDPLGAEAAAGALGQVKAKVEVCKDESVDLEEFRNYLEKRFDFEQVTVKKFRTWAERRQFNREMKRKQAESERPILPANQKLITLSVQDAPTKKEFVINPNGKSEVCILHEYMQRVLKVRPVYNFFECENPSEPFGASVTIDGVTYGSGTASSKKLAKNKAARATLEILIPDFVKQTSEEKPKDSEELEYFNHISIEDSRVYELTSKAGLLSPYQILHECLKRNHGMGDTSIKFEVVPGKNQKSEYVMACGKHTVRGWCKNKRVGKQLASQKILQLLHPHVKNWGSLLRMYGRESSKMVKQETSDKSVIELQQYAKKNRPNLHILSKLQEEMKRLAAEREETRKKPKMSIVASAQPGGEPLCTVDV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2BEG3-1", "uniprot_id": "A2BEG3_DANRE", "id": "A2BEG3-1", "name": "Microprocessor complex subunit DGCR8", "aln": "MDVNEILPPLPLEPP-DAVLAG--NDYSKAP----PPPPLQTSSDAEEMDVSSGGDGHQHTPAVDRD---EQLLLNKRTLSVSSRPSDSTDPMTTCPRTARHAPPVTKFLPDLKLLRDVKISVSFSDSSKSKDRKVLYTGFGQVS--DEDQSLESINGELHDSVMMRSVPGSSAMSTGFMGLARTREELEAEQENKVEFAVLDDLEDFSENFLEDGEPS-AFRSQMIVQQEQVHEEDLSYSYEEDFDNDVDALLEEGMPMPKKRRVAEDKYAGDSDHHSDGEAGVQPMMTKIKTILKSRGRPPTEPLPDGWIMTFHNSGIPVYLHRETRVVTWSRPYFLGTGSIRKHDPPTSSIPCLHYKKMKEQEEREQNGEVTPTAEISPVKSGEEGISLERADEPDSTATEEPTGRPTSEDPDLDLMEPGGSSIEGKDGQTGDTAQGALGQVKAKVEVCKDESIEIEDFRSYLEKCFDFEQVTVKKFRTWAERRQFNRDMKRKQAESERPILPANQKLITLSVQDAPTKKEFVINPNGKSEVCILHEYMQRVLKVRPVYNFFECENPSEPFGASVIIDGVTYGTGTASSKKLAKNKAARATLEILIPDFVKQTSEEKPVEGDELEYFNHISIEDSRVYELTNKAGLLSPYQILHECLKRNHGMGDTSIKFEVIPGKNQKSEYVMTCGKHTVRGWCKNKRVGKQLASQKILQMLHPHVKNWGSLLRMYGRESNKMVKKENSDKSVIELQQYAKKNKPNLHILNKLREEMMKLAREREEARKKPKMTIMESAQPGSEPLCTVDV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:. * .*** *. :*:: . :. * *********.** ***.*****:.. ** * **.* ::* . * ..: .********.* ** ******:********::*.:********** : : . *..:.*::* . : ** ..:. * . :. ** * :**::**:****:****::*: * * : .* :: ***:::*.** *.:.**:*************: ***** *:**.***** ****:.**********:************************:*******:********************** ************::*****. :::*:.::****. * *: * : . * * * . .. : ** .::* *****************:::*:**.**** **********************:**************************************************************************** *******:********************************** :.:*******************.******************************:***********:**************************:*******************.****:*.***************:******.**:*** :** ****:******:*: *****.********", "identical_positions": 554, "similar_positions": 121, "identity": "69.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3430", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35167-1", "uniprot_id": "COLQ_RAT", "id": "O35167-1", "name": "Acetylcholinesterase collagenic tail peptide", "aln": "MAVLNPMTLGIYLQLFFCSIVSQPTFINSVLPISAALPGLDQKKRGNHKACCLLMPPPPPLFPPPFFRGSRSPLLSPDMKN-LLELEASPSP-----CMQGSLGSPGPPGPQGPPGLPGKAGPKGEKGDLGRPGRKGRPGPPGVPGEPGPVGWPGPEGPRGEKGDVGMMGLPGSRGPMGSKGFPGSRGEKGSRGERGDLGPKGEKGFPGFPGMLGQKGEMGPKGESGIAGHRGPTGRPGKRGKQGQKGDSGIMGPPGKPGPSGQPGRQGPPGPPGPPSAGQLVMGLKGERGFPGPPGRCLCGPPANVNNPSYGDPMYGRGSPRVPAIFVVNNQEELEKLNTQNAIAFRRDQRSLYFKDSLGWLPIQLTPFYPVGLHHKAAWHLCGDGVLQP--GEECDDGNPDVSDGCIDCHRAYCGDGYRHRGVEDCDGSDFGYLKCETYLPGSYGELRCTQYCSIDSTPCRYFT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35348-1", "uniprot_id": "COLQ_MOUSE", "id": "O35348-1", "name": "Acetylcholinesterase collagenic tail peptide", "aln": "MVVLNPMTLGIYLQLFFCSIVSQPTFINSVVPISAALPGLDQKKRGSHKACCLLMPPPPPLFPPPFFRGSRSPLLSPDMKN-LLELEASPSP-----CIQGSLGSPGPPGPQGPPGLPGKTGPKGEKGDLGRPGRKGRPGPPGVPGMPGPVGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGFPGSRGEKGSRGERGDLGPKGEKGFPGFPGMLGQKGEMGPKGESGLAGHRGPTGRPGKRGKQGQKGDSGIMGPPGKPGPSGQPGRQGPPGPPGPPSAGQLVMGLKGERGFPGPPGRCLCGPPVNVNNPSYGDSMYGRGSPRVPAIFVVNNQEELERLNTQNAIAFRRDQRSLYFKDSLGWLPIQLTPFYPVGYTVKQPG-TCGDGVLQP--GEECDDGNPDVSDGCIDCHRAYCGDGYRHQGVEDCDGSDFGYLTCETYLPGSYGDLRCTQYCSIDSTPCRYFT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y215-1", "uniprot_id": "COLQ_HUMAN", "id": "Q9Y215-1", "name": "Acetylcholinesterase collagenic tail peptide", "aln": "MVVLNPMTLGIYLQLFFLSIVSQPTFINSVLPISAALPSLDQKKRGGHKACCLLTPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSP-----CMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR---PGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSPRVPVIFVVNNQEELERLNTQNAIAFRRDQRSLYFKDSLGWLPIQLTPFYPVDYTADQHG-TCGDGLLQP--GEECDDGNSDVGDDCIRCHRAYCGDGHRHEGVEDCDGSDFGYLTCETYLPGSYGDLQCTQYCYIDSTPCRYFT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q7R8-1", "uniprot_id": "A0A8M1Q7R8_DANRE", "id": "A0A8M1Q7R8-1", "name": "", "aln": "-MAMSRTGIQLQFLLYSVSAYLSPYNLDNILPIPTGQDPSDVLNR--FDPCCLLTPPPPPLFPPPPGVWKREPALPHPVVR-IIEKDEDEEEQIKERCVEGPTGPPGPAGPQGDRGIPGMVGPKGDKGDLGRPGSKGRTGRPGLPGKPGSAGLPGPEGPKGEKGDPGLMGMPGMRGPVGPKGLAGYKGEKGARGDFGPAGPKGDKGATGLPGMLGQKGEMGPKGESGVSGKRGPTGRPGKRGKQGADGERGFSGPVGPIGPPGPRGH---PGPPGVPASGLFVVGEKGEMGLPGPPGVCDCSFPS--LSPASAPLQHRNKYGKVPAIFVVGSEEELKGLHENNALAFRKDQRSLYFKDENGWEPIQLMPLQATERMRDGNG-VCGDGDVQELNGEECDDGNRVVTDDCIGCKKAYCGDGYRNEGVEECDGKDFGYQTCKSYLPGTFGQLRCTDSCFIDSTGCKYRI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:. : : : *: * .* ::.::**.:. * :* ...**** ********** *.* *. : . ::* : . . *::*. *.***.**** *:** .****:**:***** ***.* **:** **. * ******:***** *:**:** ***:*.** .* :****:**: * ****:** .*:***************.*::*:************** .*: *. ** * **.* *: ***** *.:* :::* *** *:***** * *. . .*: . : :**.****..:***: *: :**:***:*********. ** **** *: .. . **** :* ******** * *.** *::******:*:.***:***.**** .*::****::*:*:**: * **** *:* ", "identical_positions": 239, "similar_positions": 107, "identity": "51.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3432", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZXT2-1", "uniprot_id": "D3ZXT2_RAT", "id": "D3ZXT2-1", "name": "Cohesin subunit SA", "aln": "----------MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKG----------------------------PAEKGKSGNGGGKPPSGPNRMN---------GHHQQNGVEN------MMLFEVVKMGKSA-MQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVTAEMFRHMQNSE---------IIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLVRQC-QYSIIYDEY-----------MMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDAIAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKE-----LNSKLELFTSRFKDRIVSMTLDKE-YDVAVQAIKLLTLVLQS----------SEEVLTAEDCENVYHLVYSAHRPVAVAAGEFLYKKLFSRRDPEEDGIMKRRGRQGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVGRGTG-KRVLTAKEKKTQLDDRTRITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELADKFNRLLEDF--LQEGEE-PDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTG-----IENGD--MPEQIVIHALQCAHYVILWQLAKIT----ESTSTKEDLLRLKKQMRVFCQICQHYLTN-VNTTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDSNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQIDKIQCAKTLILSLQQLFNEMIQEN----GYNFDRSSSTFSGIKELARRFALTFGLDQLKTREAIAMLHKDGIEFAFKEP-----NPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGMSSRGSTVRSKKSKPSTGKRKVLEGMQLALPEESSSSDSMWLSREQTL-HTPVMMQTPQLTSTIMREPKRLRPEDSFMSVYPMQTEHHQTP-------LDYN-------------------------------QRGTSIMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMDESVLGVSMF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35638-1", "uniprot_id": "STAG2_MOUSE", "id": "O35638-1", "name": "Cohesin subunit SA-2", "aln": "----------MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKG----------------------------PAEKGKSGNGGGKPPSGSNRMN---------GHHQQNGVEN------MMLFEVVKMGKSA-MQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVTAEMFRHMQNSE---------IIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLVRQC-QYSIIYDEY-----------MMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDAIAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKE-----LNSKLELFTSRFKDRIVSMTLDKE-YDVAVQAIKLLTLVLQS----------SEEVLTAEDCENVYHLVYSAHRPVAVAAGEFLYKKLFSRRDPEEDGLMKRRGRQGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVGRGTG-KRVLTAKEKKTQLDDRTRITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELADKFNRLLEDF--LQEGEE-PDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTG-----IENGD--MPEQIVIHALQCAHYVILWQLAKIT----ESTSTKEDLLRLKKQMRVFCQICQHYLTN-VNTTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDSNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQIDKIQCAKTLILSLQQLFNEMIQEN----GYNFDRSSSTFSGIKELARRFALTFGLDQLKTREAIAMLHKDGIEFAFKEP-----NPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGMSSRGSTVRSKKSKPSTGKRKVVEGMQLALPEESSSSDSMWLSREQTL-HTPVMMQTPQLTSTIMREPKRLRPEDSFMSVYPMQAEHHQTP-------LDYN-------------------------------RRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMDESVLGVSMF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N3U4-1", "uniprot_id": "STAG2_HUMAN", "id": "Q8N3U4-1", "name": "Cohesin subunit SA-2", "aln": "----------MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKG----------------------------PAEKGKGGNGGGKPPSGPNRMN---------GHHQQNGVEN------MMLFEVVKMGKSA-MQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVTAEMFRHMQNSE---------IIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLVRQC-QYSIIYDEY-----------MMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDAIAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKE-----LNSKLELFTSRFKDRIVSMTLDKE-YDVAVQAIKLLTLVLQS----------SEEVLTAEDCENVYHLVYSAHRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVGRGTG-KRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELADKFNRLLEDF--LQEGEE-PDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTG-----IENGD--MPEQIVIHALQCTHYVILWQLAKIT----ESSSTKEDLLRLKKQMRVFCQICQHYLTN-VNTTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDNNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQIDKIQCAKTLILSLQQLFNEMIQEN----GYNFDRSSSTFSGIKELARRFALTFGLDQLKTREAIAMLHKDGIEFAFKEP-----NPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTGKRKVVEGMQLSLTEESSSSDSMWLSREQTL-HTPVMMQTPQLTSTIMREPKRLRPEDSFMSVYPMQTEHHQTP-------LDYN-------------------------------RRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMDESVLGVSMF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NE13-1", "uniprot_id": "A0A8M1NE13_DANRE", "id": "A0A8M1NE13-1", "name": "Cohesin subunit SA", "aln": "----------MIAAQELQADFYQEGHS---LLSDTDLEDHEGRNGKLAKG---KKGKKS----------------------------IGEKLKGSEVRG-------RVN---------GHHQENDMEN------LSLFEIVRLGKSA-TQSVVDDWIESYKTDRDSALLELINFFIHCSGCKGTVSFEMFRNMQNSE---------IIRKMTEEFDEDSGDYPLAMAGPAWKKFKTNLCEFIATLVRQC-QYSIIYDEY-----------MMDTLISLLTGLSDSQVRAFRHTSTLAAMKMMTALVNVALNLSINLDNTQRQYETERNKSIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFIHRYRDVIAEIRVVCIEEIGMWMKMYSEAFLNDSYLKYVGWTMYDKQGEVRLKCLTALQGLYYSRE-----LNARLELFTSRFKDRIVSMTLDKE-YDVAVQAIKLLTLVLQS----------SDEVLMAEDCESVYHLVYSAHRPVAVAAGEFLYKKLFSHHGPEDEGRP-RRGRQCLNANLIRTTVLFFLESELHEHGAYLVDSLWDCASELLKDWESMISLLLDEPFPGEEALSDAQEVALIEIMFCAVRQTCECHPPIGRGTG-KRVLTAKEKKTQLDDRTKITETFAVALPLLLAKYSMDPEKVTNLLQFPRYFDLEIYTTGRLEKHLDALLRQVRDVVEKHTDTDVLEACSMTFQALCNDEFTIYNRVDLVRSQMLDEQIDKFHRLLEDF--LLEGEE-PDEDDTYQVLSTLKRITAFHNAHDLTKWDLFTSNYRLLNSG-----LQNGD--MPEQIVAHALQCTHYVILWHLAKVS----EGSASKDDMVLLRRQVRAFCLMCQRYLNS-MSTAVKEQAFTILCDALLIFSYQIVASGREILEPLVFSPDASLQSELLNFILDHVFVEQDED-----GSTDDEAGKIEALHRRRNLLAAFCKLIIFNVVEMKTGADVFKQYMRYYTDYGDIIKETMSKARQIDKIQCAKTLILSLQQLFNEMLSDL----GCNFDRSTSAFCGIKELARRFALTFGLDQLKTREAIAMLHKDGIEFAFKEP-----SPQGEGGPPLNLAFLDILSEFSSKLLRQDKKTVHVYLERFMTFQMALQRDDCWLPLISYRNSLQAGADDDTLSVISGMSR--SSARSRRGKPPAASKRKLPDEDSSCS---SSDVSMWVNRVQTVPHSPVMMSSPHIVSTVLRDAKKLRPEQGYIGVYSMSNEAQHTPLQQPHQHMDYNSQVAWMMAQKQQQERANLQYGKMRGHIQHTIRRGSGLMEDDEEPIVEDVMMSSEERLDDLNEGMDFDTMDIDLPPSKNRRERSELKQDYFDPSSIMDDSVLNVSMF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VM62-1", "uniprot_id": "Q9VM62_DROME", "id": "Q9VM62-1", "name": "", "aln": "--MMARRGGKRIRMDDPPPDYEELHSDALNESTSDADSPTKRMTRLRARGGVRDKPPIIDDDEDDF------------------FAPIARKRKTPATRKGPTERKERVERPRKEPVDKGHHERIDSEREITTDENSLYYIVRHSKNP-IASIVDQWIEQYKANRETALVALMQFFINASGCKGKISEDIQYPVDHTS---------IIRRMTEEFDEESGEYPLIMSGTQWRKFKNNFCDFVQTLVKQC-QYSIIYDQF-----------LMDNVISLLTGLSDSQVRAFRHTATLAAMKLMTALVDVALLVSNNFDNAAKQFEAERVKSRDRRASDRLDSLMTKRSELEENMDEIKSMLTYMFKSVFVHRYRDSLPDIRAICMAEIGIWMENYPQNFLDDSYLKYIGWTLHDKIGEVRLRCLQSLLPLYEKDE-----LKGKLELFTSKFKDRIVAMTLDKE-FEVSVHAVKLVISILKI----------HPEILADKDCEIVYELVYSSHRGVAQAAAEFLNVRLFHLTADMEETKTKRGKVRMPNTPLVRDLVQFFIESELHEHGAYLVDSFID-SNDMVRDWECMTDLLLEEPGPNEEVLDNKQESTLIEIMVSSVKQSATGEVPVGRASNRKCTLSAKELKAIQDEKAKLTEHFIVTLPSLLEKYQADSEKLANLLAVPQYFDLNLYTTNRQEGNLQALLDRINQVMSMHTGREVLETCAKTLECLCAEGSATYTRCNIARSNIIESAVNKYKDAIEEWRNLIQGEETPNEDDIYNITITLKVLSILYSSHNLNPWELFKSLFQDVEEAQS---KENIDRCLPNEALVYCIEACYFSISWGLQYVEN-ECESVNVTEVVAELRNNLDTFMGACFELTRDGPTVQIQEAAYQSICDLLIIFSDKLARSEIEHIRGLEYKSRMDEHLILDNFVQHYVFSLKQDV--------AQDETRIEELHKKRNFLACYCKLVVYNIIPTMRAASIFKYYVKCYNDYGDIIKATLGKAREINKVNFAMTLLLSLITVFKSLQEQSE---DGIVSKSSQEFVDLKELAKRFALTFGFDAIKNRESVAAIHRGGIYFAANK------EPDDPVRAPTRLLFLEVLNEFNYKLLKQDKKVIMSFLDKIIPPAMPSSRAEEWQPLILYRNSLLHG-ETDQAPVAS-------------KRAYTRKRR----------------------------------------------------DHD----------------------------------------------------------------EEEEE----------EEDEEEHND------------------------PDYRG---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0F4-1", "uniprot_id": "Q9W0F4_DROME", "id": "Q9W0F4-1", "name": "", "aln": "-------------MSDISFDDAVLNDS--QASNQMDFEIREECSIAPNDEPVCVDGTVG----------------------------------------------DATN---------KSLLQMILSR-------KRLSPTNKRNSH-IESVAKYWGEFYLDSPTAALVALLQFVVEVSGSHYQIPDDTSMPFSYSD---------ILSNSSSHFSN-THIYPLIRK--PADVFVNQVGSFLNALLLVANKFRSDSYQL-----------FLVQLTNFVMACSESNIRTFRHTATMIGLKIMTILSDLKS----------------------------------------LDDEIAMTVWMQMFNSMFVARSRDIVTDIRLLCISELGQWFARYPHCHLQPTSLRIFYEALNDGSGDVIQCSLDNISVLCRKDV-----LFSEIVALTSEFREILVELCLGKE-DAIAEKSVQFLTHFHVL----------SAEILTDDVCRVLEQLIMAANRGLAQAAADLFILRRNGLDG-------------ETFCQRVKHLLQLFIECG-HEQADYLVDSLID-NCELVLDWKSMIAVLLENPKSRE--LSDIHCSSLIAILLAGVKQATAGEIPPGRYTK------DLKREPRQGAQERATKCLAPVLPELLRTYANRLQDIERLLELPKYFCFDYYHEQNRMGQLNELVEHFELIIFDQTSSTTVLQITVKTLEFLNRMIPIP-----LTKQLLNSAVTNYKMAWHRT--QDTSPSRSTHNESNRLLATLRLLTVLSGHFNLSKWDLTEPLLFSLKMLLRQRRLPNGDD-LPPEAFSLYLKACFCCLCWDMENLEGTALNNVDMDEYCDVLHHNLEDYLYVTFSLVGKSNTEPLAYPCFSYTCDLFVLHG-NLCGSSNPSIRSVAHVPSGNELDILEGFLMEHFLELSPSD--------LMLETNSDQLQRIRSILTSYLKVVCLGVVPTMRASKFYEYYVKYHAPFGDVMRCSMELALQRNPIHFAMTMLHTCLLLYAKVFPDDTRHAAGQRALRPAEFSELMELANRLAKILISNPMEHRECVIALHRSGILFVFELA-----QKQP-TEATKKLPFLRVLKVFVPLLLVQDKTRILNFFEPYEQLIIPTCNRNDIAHLKEYRNALRPRKTKSYPQAT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40541-1", "uniprot_id": "SCC3_YEAST", "id": "P40541-1", "name": "Cohesin subunit SCC3", "aln": "MTAVRRSTRIRTKSQVIEEDYDDEQNTSAQHVESDKITAKTQHEEEEEQDTGESEESSSEDDYEDQDDDDYVDTATAKRKSRKRKPKSASNTSSKRQKKKPTSAQKSAVSHAPAYHRSKKDQDQYLEIAKDFQPTELFDILSTSEDVSIEELLREWLETYSENRDKFLQEFINLLLNCCGSVARVEDHDVHSNESSNETIGEIQLLFQRQKLHEFYLLISKENKKRKNFKMGPLYQNFAEFMTKLLEVANDLQLLYVESDEDDTQIVTGNLVLDLLTWLSSFSVCKIRCFRYISTLTLYLFQDYLTQQAVNLEKNYLAKLSKQLSLEEKKK-RPNNKTLEKLESTIAETQGSKVVIDSIIDNIVKLCFVHRYKDVSDLIRSESMLHLSIWIKNYPEYFLKVTFLKYFGWLLSDNSVSVRLQVTKILPHLIIQNHNSKSTDNSAIRQVFERFKTKILEVAIRDVNLDVRIHSIQVLTEASSLGYLDDSEILIISSLMFDEEFDPFKTSSFNKRSKFLSTVAKFLARVIKEKFDEFIKTHEDLPKEVDGLEVGPVVQVGIFIKILNDSLIYHLKDCAEVDSRTKIRMLTQAAEFLSPYISTHLKTICNLLISDTESNELIQKLQNSANNNSDDEDVD-DEELDITPLFPIDRNSTILYLNVFHGLCAGANNPKIQTKDSVKEIVLPLFYDLLNAASIESADILCPLLESFITFSLDDWISIGYETELKKITDKTIKAFMDSTIGN-SKVDMKYDIFAKFIHHIHHFEKKELQEKFLNQIATLKIHLKKFLQEKMDPNNSRDDYKDLTCSLYELYINKLTILGRDYPIEVDEELLQLFLNNFVSRIPIMFQDFDDSTAQEINFKMLVLLATWNLEKWREIIEKVRDYENSISKDLRSVWKPIAAIIGRLNTLVISLAATNETFENINSLFYLKWSACTSLMDIIVA------------------IKIFELKLPADATTWRYSMSEQFPFYLHDNASKVLLKIFLYLESLFAKQVDVQLERVADEDANLNDLPETGFFENIETEFL-----LFTVKLKGLMKLNILDERFASRVALNKEKLGPLFKKIVDDTIMENPEPNKKNIQKAKSNQTQREKAPLQPNSERETDHANTENNDPDIPMTIDLEPIEESSQNNSELAPIEEHPTVVDAIDNSDEITQD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . . :. .: * * * . * ::::.:. .*. : . . :. : . .* : .. .*: *: . . : :: : . : . * .::* **: :*: : * : . .: :.: *: * :* ** .: .:. *: *.. .*. : *: . : * .* : * . . : . ..*: :: : : . : ::::.: .:: . . . . :...:: : :*:: .. :* *. : .* . : : . * . . .. . . * . :. . : .* :: : . * *: . . . . :: . :: . . . .: . : . :. : : : : . :: : : . : :: : . . :: : . . . .: . :. : : . . : :: . .:: : : . * . .: .: : : : * .*:* . : : . : . * : . . . : . ::: . . . : : . : . ", "identical_positions": 42, "similar_positions": 228, "identity": "3.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3435", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6J9G1-1", "uniprot_id": "STYK1_MOUSE", "id": "Q6J9G1-1", "name": "Tyrosine-protein kinase STYK1", "aln": "MGEKGHLSRVLLECSLSDKLCVVREKQYEVIIVPALLVGGFLILLAIILWLFIRGQRSQRQSPGP----------RGTASVPASRGRSQEAAGHGEKVLLPLKETS------------VEGFLRAATPRLAK-LQVPREQLLEVLEQIHSGSCGTLYHATMTT---KDHPKPKSVVLKALEDPVGLQEVQDFIGRIQFYQYLGKHKNLVQLEGCCTERLPLYMMLEDVVPGDLLSFLWTCRRDVMTMDGLLYDLTEKQIYHIGKQILLALEFLQEKHLFHGDVAARNILIQSDLTPKLCHLGLAYEVHAHGAISSARSSTIPLKWLAPERLLLRPASIRGDIWSFGILLYEMVTLGAPPYPEVPPTSILQYLQRKKIMKRPSSCSHAMYNIMKCCWRWSEDSRPLLGQLLQRLEAASRSADDKAVLQVPELVVPELYADVAGIRAESISYSFSVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZHY0-1", "uniprot_id": "D3ZHY0_RAT", "id": "D3ZHY0-1", "name": "Tyrosine-protein kinase STYK1", "aln": "MGEKGRLSRLLLECSLSDKLCVVQEKQYEVIIVPALLVGSFLILLAIILWLFIRGQRSQRQHPGP----------RGTTSVPASRGRSQEAVGHGEKVFVPLKETS------------VESFLRAVTPSLAK-LQVPREQLLEVLEQIHSGSCGTLYHAKMTT---MEHPNPKSVVLKALEGSVGLQEVQDFIGRIQFYQYLGKHKNLVQLEGCCTERLPLYMMLEDVVPGDLLNFLWTCRRDVMTMDGLLYDLTEKQIYHIGKQVLLALEFLQEKHLFHGDVAARNILIQSDLTPKLCHLGLAYEVHTHGAISSARSSTIPLKWLAPERLLLRPASIRGDVWSFGILLYEMVTLGAPPYPEVPPTSILQYLQRKKIMKRPSSCTHAMYNIMKYCWRWSEDSRPLPGELRLRLEAASRTANDKAVLQVPELVVPDLYADVAGISTESLSDSYSVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6J9G0-1", "uniprot_id": "STYK1_HUMAN", "id": "Q6J9G0-1", "name": "Tyrosine-protein kinase STYK1", "aln": "MG----MTRMLLECSLSDKLCVIQEKQYEVIIVPTLLVTIFLILLGVILWLFIREQRTQQQRSGP----------QGIAPVPPPRDLSWEAG-HGGNVALPLKETS------------VENFLGATTPALAK-LQVPREQLSEVLEQICSGSCGPIFRANMNT---GDPSKPKSVILKALKEPAGLHEVQDFLGRIQFHQYLGKHKNLVQLEGCCTEKLPLYMVLEDVAQGDLLSFLWTCRRDVMTMDGLLYDLTEKQVYHIGKQVLLALEFLQEKHLFHGDVAARNILMQSDLTAKLCGLGLAYEVYTRGAISST--QTIPLKWLAPERLLLRPASIRADVWSFGILLYEMVTLGAPPYPEVPPTSILEHLQRRKIMKRPSSCTHTMYSIMKSCWRWREADRPSPRELRLRLEAAIKTADDEAVLQVPELVVPELYAAVAGIRVESLFYNYSML", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QCV8-1", "uniprot_id": "E9QCV8_DANRE", "id": "E9QCV8-1", "name": "", "aln": "--MAASSSAASSECEAGDALCEIRVYEQEVIIVPVIFFMMFLITLLFIMLLRFCPEKVERLQPASSRVSRTRRNLQGIDAPLGLNALEGEPIALDTTTYMTFNPATPARLDHANNVAFTDGMFGATASAFAKPRELPRQRLPENFNGVAPLPASYSLKSDSPISLYRARMENRNVVLRVLKDSASNQESQSFLGFAAFLSQLGPHPFLPELLGVISLRAPLITVIEEMENRDLLGFLWRCRQDNVGPDG-MCQMTEKKIFNMASHVASALDFLHGKDLHHCNLKARNVLVSRICTAKLWGLDDLYVRTSGSGNYSE--DPGRKKWQAPELLAKRPSTPKSDIWSFGLLLYEMVTLGEVPFAEIPVKELLQHHQRVKPIRKPNNCSNSLYSIIKSCCHWKEQDRPSLAEVRRKLQSGEKSASDSSVLRVPEPINIQQYLKEAGYGESNSYTVF---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **. .* ** :: : ******.::. *** * .*: * : :: :: ... :* . . . *. . .. :.:: :: .:.:: *.:. :** ::**::* * :: : . ... :: : :.*:*:.*: ... :* *.*:* * . ** * * :* * : : ** ::*:: ***.*** **:* : ** : ::***:::::..:: **:**: *.*.* :: ***:*:. *.** *. * : .. * .. ** *** * **:: :.*:****:********* *:.*:* ..:*:: ** * :::*..*::::*.*:* * :* * .** :: :*::. ::*.*.:**:*** : : * ** .. : ", "identical_positions": 124, "similar_positions": 152, "identity": "27.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3445", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M5C7-1", "uniprot_id": "A0ABK0M5C7_RAT", "id": "A0ABK0M5C7-1", "name": "Endoribonuclease Dicer", "aln": "MKSPALQPLSMAGLQLMTPASSPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAALDHNTIVCLNTGSGKTFIAVLLTKELAHQIRGDLSPHAKRTVFLVNSANQVAQQVSAVRTHSDLKVGEYSNLEVNASWTKERWSQEFTKHQVLIMTCYVALNVLKNGYLSLSDINLLVFDECHLAILDHPYREIMK--LCDSCPS-CPRILGLTASILNGKCDPDELEEKIQKLEKILKSGAETATDLVVLDRYTSQPCEIVVDCGPFTDRSGLYERLLMELEEALDFINDCNVSVHSKE------------RDSTLISKQILSDCRAVLVVLGPWCADKVAGMMVRELQKYIKHEQEELHRKFLLFTDTLLRKIHALCEEYFS--------PASLDLKYVTPKVMKLLEILRKYKPYE--------------------------------------------RQQFESVEWYNNRNQDNYVSWSDSEDDDDDEEIEEKEKPE--TNFPSPFTN-----------------ILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRSKQMEAEFRKQEEVLRKFRAHETNLLIATSVVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPISNYVMLAD-------------------------------------------------------------------------------------------------------------------------------------------------TDKIKSFEEDLKTYKAIEKILRNKCSKSVDGAEADVHAVVDDDDVFPPYVLRPDDG-GPRVTINTAIGHINRYCARLPSDPFTHLAPKCRTRELPDG---TFYSTLYLPINSPLRASIVGPPMGCVRLAERVVALICCEKLHKIGELDEHLMPVGKETVKYEE------ELDLHDEEETSVPG--RPGSTKRRQCYPKAIPECLRESYPKPDQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFTLSQQMLELVTRLHQYIFSHILRLEKPALEFQPAGAESAYCVLPLNVVNDSSTLDIDFKFMEDIEKSEARIGIPSTKYSKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTASDAGVGVRSLP-ADFRYPNLDFGWKKSIDSK-SFISTCNSSLAESDNYCKHSTTVVPENAAHQGATRP-SLENHDQMSVNCKRLPAE----------SPAKLQSEVSVDLTAINGLSYNKSLANGSYDLVNR-DFCQGNQ-------------LTYFKQEIPVQPTTSYPIQNLYNYENQPTPSNECPLLSNKYLDGN--------ANTSTSDGSPAGSPRPAMMTAVEALEGRTDSEQSPSVGHSSR---TLGPNPGLILQALTLSNASDGFNLERLEMLGDSFLKHAITTYLFCTYPD------AHEGRLSYMRS-------KKVSNCNLYR----------LGKKQGLPSRMVVS-IFDPPVNWLP--------------------PGYVVNQD----KSNSEKWEKDEMTKDCLLANGKLGEDCEEEEEE--ELAWRAPKEEAEYEDDLLEYDQEHIQFIDSMLMGSGAFVKKIPLSPFSTSDSAYEWKMP----------------KKASLGSVPFSSDLEDFDYSSWDAMCYLDP---SKAVEEDDFVVGFWNPS--------------------------EENCGVDTGKQS------------ISYDLHTEQCIADKSIADCVEALLGCYLTSCGERAAQLFLCSLGLKVLPVIKRTSRDKASYPAQENSSSQQKSPSGSCAAA--VSPRSSAGKDLEYGCLKIP-PRCMFDHPDAEKTLNHLISGFENFEKKINYIFKNKAYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALVNNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVQFQLEKNEMQGMDSELRRSEEDEEKEEDIEVPKAMGDIFESLAGAIYMDSGMSLEVVWQVYYPMMRPLIEKFSANVPRSPVRELLEMEPETAKFSPAERTYDG-KVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSLKANQPLVPNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R418-1", "uniprot_id": "DICER_MOUSE", "id": "Q8R418-1", "name": "Endoribonuclease Dicer", "aln": "MKSPALQPLSMAGLQLMTPASSPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAALDHNTIVCLNTGSGKTFIAVLLTKELAHQIRGDLNPHAKRTVFLVNSANQVAQQVSAVRTHSDLKVGEYSDLEVNASWTKERWSQEFTKHQVLIMTCYVALTVLKNGYLSLSDINLLVFDECHLAILDHPYREIMK--LCESCPS-CPRILGLTASILNGKCDPEELEEKIQKLERILRSDAETATDLVVLDRYTSQPCEIVVDCGPFTDRSGLYERLLMELEAALDFINDCNVAVHSKE------------RDSTLISKQILSDCRAVLVVLGPWCADKVAGMMVRELQKYIKHEQEELHRKFLLFTDTLLRKIHALCEEYFS--------PASLDLKYVTPKVMKLLEILRKYKPYE--------------------------------------------RQQFESVEWYNNRNQDNYVSWSDSEDDDDDEEIEEKEKPE--TNFPSPFTN-----------------ILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRSKQMEAEFRKQEEVLRKFRAHETNLLIATSVVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPISNYVMLAD-------------------------------------------------------------------------------------------------------------------------------------------------TDKIKSFEEDLKTYKAIEKILRNKCSKSADGAEADVHAGVDDEDAFPPYVLRPDDG-GPRVTINTAIGHINRYCARLPSDPFTHLAPKCRTRELPDG---TFYSTLYLPINSPLRASIVGPPMDSVRLAERVVALICCEKLHKIGELDEHLMPVGKETVKYEE------ELDLHDEEETSVPG--RPGSTKRRQCYPKAIPECLRESYPKPDQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFTLSQQMLELITRLHQYIFSHILRLEKPALEFKPTGAESAYCVLPLNVVNDSGTLDIDFKFMEDIEKSEARIGIPSTKYSKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTASDAGVGVRSLP-VDFRYPNLDFGWKKSIDSK-SFISTCNSSLAESDNYCKHSTTVVPEHAAHQGATRP-SLENHDQMSVNCKRLPAE----------SPAKLQSEVSTDLTAINGLSYNKNLANGSYDLVNR-DFCQGNQ-------------LNYFKQEIPVQPTTSYPIQNLYNYENQPKPSNECPLLSNTYLDGN--------ANTSTSDGSPAVSTMPAMMNAVKALKDRMDSEQSPSVGYSSR---TLGPNPGLILQALTLSNASDGFNLERLEMLGDSFLKHAITTYLFCTYPD------AHEGRLSYMRS-------KKVSNCNLYR----------LGKKKGLPSRMVVS-IFDPPVNWLP--------------------PGYVVNQD----KSNSEKWEKDEMTKDCLLANGKLGEACEEEE----DLTWRAPKEEAEDEDDFLEYDQEHIQFIDSMLMGSGAFVRKISLSPFSASDSAYEWKMP----------------KKASLGSMPFASGLEDFDYSSWDAMCYLDP---SKAVEEDDFVVGFWNPS--------------------------EENCGVDTGKQS------------ISYDLHTEQCIADKSIADCVEALLGCYLTSCGERAAQLFLCSLGLKVLPVIKRTSREKALDPAQENGSSQQKSLSGSCAAP--VGPRSSAGKDLEYGCLKIP-PRCMFDHPDAEKTLNHLISGFETFEKKINYRFKNKAYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALVNNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVKFQLEKNEMQGMDSELRRSEEDEEKEEDIEVPKAMGDIFESLAGAIYMDSGMSLEVVWQVYYPMMQPLIEKFSANVPRSPVRELLEMEPETAKFSPAERTYDG-KVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSLKANQPQVPNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPY3-1", "uniprot_id": "DICER_HUMAN", "id": "Q9UPY3-1", "name": "Endoribonuclease Dicer", "aln": "MKSPALQPLSMAGLQLMTPASSPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAALDHNTIVCLNTGSGKTFIAVLLTKELSYQIRGDFSRNGKRTVFLVNSANQVAQQVSAVRTHSDLKVGEYSNLEVNASWTKERWNQEFTKHQVLIMTCYVALNVLKNGYLSLSDINLLVFDECHLAILDHPYREIMK--LCENCPS-CPRILGLTASILNGKCDPEELEEKIQKLEKILKSNAETATDLVVLDRYTSQPCEIVVDCGPFTDRSGLYERLLMELEEALNFINDCNISVHSKE------------RDSTLISKQILSDCRAVLVVLGPWCADKVAGMMVRELQKYIKHEQEELHRKFLLFTDTFLRKIHALCEEHFS--------PASLDLKFVTPKVIKLLEILRKYKPYE--------------------------------------------RQQFESVEWYNNRNQDNYVSWSDSEDDDEDEEIEEKEKPE--TNFPSPFTN-----------------ILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRNKQMEAEFRKQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPISNYIMLAD-------------------------------------------------------------------------------------------------------------------------------------------------TDKIKSFEEDLKTYKAIEKILRNKCSKSVDTGETDIDPVMDDDDVFPPYVLRPDDG-GPRVTINTAIGHINRYCARLPSDPFTHLAPKCRTRELPDG---TFYSTLYLPINSPLRASIVGPPMSCVRLAERVVALICCEKLHKIGELDDHLMPVGKETVKYEE------ELDLHDEEETSVPG--RPGSTKRRQCYPKAIPECLRDSYPRPDQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFMLSLQMLELITRLHQYIFSHILRLEKPALEFKPTDADSAYCVLPLNVVNDSSTLDIDFKFMEDIEKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTASDAGVGVRSLP-ADFRYPNLDFGWKKSIDSK-SFISISNSSSAENDNYCKHS-TIVPENAAHQGANRTSSLENHDQMSVNCRTLLSE----------SPGKLHVEVSADLTAINGLSYNQNLANGSYDLANR-DFCQGNQ-------------LNYYKQEIPVQPTTSYSIQNLYSYENQPQPSDECTLLSNKYLDGN--------ANKSTSDGSPVMAVMPGTTDTIQVLKGRMDSEQSPSIGYSSR---TLGPNPGLILQALTLSNASDGFNLERLEMLGDSFLKHAITTYLFCTYPD------AHEGRLSYMRS-------KKVSNCNLYR----------LGKKKGLPSRMVVS-IFDPPVNWLP--------------------PGYVVNQD----KSNTDKWEKDEMTKDCMLANGKLDEDYEEEDEEEESLMWRAPKEEADYEDDFLEYDQEHIRFIDNMLMGSGAFVKKISLSPFSTTDSAYEWKMP----------------KKSSLGSMPFSSDFEDFDYSSWDAMCYLDP---SKAVEEDDFVVGFWNPS--------------------------EENCGVDTGKQS------------ISYDLHTEQCIADKSIADCVEALLGCYLTSCGERAAQLFLCSLGLKVLPVIKRTDREKALCPTRENFNSQQKNLSVSCAAASVASSRSSVLKDSEYGCLKIP-PRCMFDHPDADKTLNHLISGFENFEKKINYRFKNKAYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALVNNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVQFQLEKNEMQGMDSELRRSEEDEEKEEDIEVPKAMGDIFESLAGAIYMDSGMSLETVWQVYYPMMRPLIEKFSANVPRSPVRELLEMEPETAKFSPAERTYDG-KVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSLKANQPQVPNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6TV19-1", "uniprot_id": "DICER_DANRE", "id": "Q6TV19-1", "name": "Endoribonuclease Dicer", "aln": "----------MAGLQLVTPASSPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAALEHNTIVCLNTGSGKTFIAVLLIKELSHQIRGE---NGKRTVFLVNAASSVAQQASTVRTHSDLQVGDYMSEDMTS-WPEEMWNREMIENQVLVMTCHIFLHVLKNGVLPLSKINLLVFDECHLAITGHPYREIMK--ICEGCPS-CPRILGLTASILNGKCDPCDLEEKIQNLEKILQSNAETATDLVVLDRYASQPREEVLDCGQYQDQSGLSERLLNELDEALNFLNDCNLSVHRED------------RDPTFISKQVLNDCRAVLTVLGPWCADKAAGIMVRELQKYIKHEQEELNRKFLLFTDTILRKIHALCEEHFS--------PASLDLKFVTPKVIRLLEILHEYKPFE--------------------------------------------RQQFESVEWYNNRNQDNYVSWSDSEDDDEDEEAEAKEKTE--ANFPSPFTN-----------------ILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHSIGKNQPRNKQMEVEFRKQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPVSNYIMLAD-------------------------------------------------------------------------------------------------------------------------------------------------SERTKTFQEDLKTYKAIEKILRNKCSKSAECNDFELEPVTDDDNVLPPYVLRSEDG-GPRVTMNTAIGHVNRYCARLPSDPFTHLAPKCKTVEMNTG---GYRSTLFLPINSPLRVPVTGPVMNCARLAEKAVALLCCEKLHKIGELDDHLMPVGKETVKYEE------ELDLHDEEETSVPG--RPGSTKRRQCSPKAIPECLRGCYPVPEQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPRIPHFPVYTRSGEVTISIELQKSGFSLSAEQLELITRLHQYIFSHILRLEKPALEFKPVEADSAYCVLPLNIVEDSNTLDLDFKFMEDIEKSEARIGIPNTQYTKQNPFIFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLSNVNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRSQTAIDAGVGAQTLP-PDFRYPNLDFGWKKSIDSK-SFISCPSACMEEDDDHCKLGTSSDSNHTAPESCSMEVSQPPEGAPNTPDEKLETL----------TLP------VTDLNKDCFPNLPNGTQADSDDLPHRSDVCQCSQ-------------LGPLERDLSTQTTTSVSVRPSPAGEPQPWPSDECTGRSSDLCDPH--------VKKPTSKHCPKSETATSTPAPSETSSEDCRSACAGPAWDSPK---TLGPNPGLILQALTLSNASDGFNLERLEMLGDSFLKHAITTYLFCTYPD------AHEGRLSYMRS-------KKVSNCNLYR----------LGKKKGLPSRMVVS-IFDPPVNWLP--------------------PGYVVNQD----KSSTDKWDSDENKD---LANGKASDDEDEDDDDEPEEAEVEPSKEDVNVEDDLEYYYEHIRFIDSMLIGSGAFGKKISLQP---TDPGYEWKAP----------------KKAHNSHFSPDGGADEFDYSSWDAMCYLDP---SKAGEEDDFVVGFWNPS--------------------------EENCGTDIGKQS------------ISYDLHTEQCIADKSIADCVEALLGCYLTSCGERAAQLFLCSLGLKVLPPEKQS---------------------------------SGGSAELQYGWLKIP-PRCMFEHPDAERTLNHLISGFLNFESKINYTFKNKAYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALVNNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVQFQLEKNEMQGMDSELRRSEEDEEKEEDIEVPKAMGDIFESLAGAIYMDSGMSLETVWQVYYPMMRPLIEKFSANVPRSPVRELLEMEPETAKFSPAERTYDG-KVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSLKANQPQVQNN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCU9-1", "uniprot_id": "DCR1_DROME", "id": "Q9VCU9-1", "name": "Endoribonuclease Dcr-1", "aln": "---------------------------MAFHWCDNNLHTTVFTPRDFQVELLATAYERNTIICLGHRSSKEFIALKLLQELSRRAR----RHGRVSVYLSCEVGTSTEPCSIYTMLTHLTDLRVWQEQPDMQIPFDHC---WTDYHVSILRPEGFLYLLETRELLLSSVELIVLEDCHDSAVYQRIRPLFENHIMPAPPADRPRILGLAGPLHSAGCELQQLSAMLATLEQSVLCQIETASDIVTVLRYCSRPHEYIVQCAPF-EMDELSLVLADVLNTHKSFLLDHRYDPYEIYGTDQFMDELKDIPDPKVDPLNVINSLLVVLHEMGPWCTQRAAHHFYQCNEKLKVKTPHERHYLLYCLVSTALIQLYSLCEHAFHRHLGSGSDSRQTIERYSSPKVRRLLQTLRCFKPEEVHTQADGLRRMRHQVDQADFNRLSHTLESKCRMVDQMDQPPTETRALVATLEQILHTTEDRQTNRSAARVTPTPTPAHAKPKPSSGANTAQPRTRRRVYTRRHHRDHNDGSDTLCALIYCNQNHTARVLFELLAEISRRDPDLKFLRCQYTTDR-VADPTTEPKEAELEHRRQEEVLKRFRMHDCNVLIGTSVLEEGIDVPKCNLVVRWDPPTTYRSYVQCKGRARAAPAYHVILVAPSYKSPTVGSVQLTDRSHRYICATGDTTEADSDSDDSAMPNSSGSDPYTFGTARGTVKILNPEVFSKQPPTACDIKLQEIQDELPAAAQLDTSNSSDEAVSMSNTSPSESSTEQKSRRFQCELSSLTEPEDTSDTTAEIDTAHSLASTTKDLVHQMAQYREIEQMLLSKCAN-TEPPEQEQSEAERFSACLAAYRPKPHLLTGASVDLGSAIALVNKYCARLPSDTFTKLTALWRCTRNERAGVTLFQYTLRLPINSPLKHDIVGLPMPTQTLARRLAALQACVELHRIGELDDQLQPIGKEGFRALEPDWECFELEPEDEQIVQLSDEPRPGTTKRRQYYYKRIASEFCDCRPVAGAPCYLYFIQLTLQCPIPEEQNTRGRKIYPPEDAQQGFGILTTKRIPKLSAFSIFTRSGEVKVSLELAKERVILTSEQIVCINGFLNYTFTNVLRLQKFLMLFDPDSTENCVFIVPT-VKAPAGGKHIDWQFLELIQANGNTMPRAVPDEERQ-AQPFDPQRFQDAVVMPWYRNQDQPQYFYVAEICPHLSPLSCFPGDNYRTFKHYYLVKYGLTIQNTSQPLLDVDHTSARLNFLTPRYVNRKGVALPTSSEETKRAKRENLEQKQILVPELCTVHPFPASLWRTAVCLPCILYRINGLLLADDIRKQVSADLGLGRQQIEDEDFEWPMLDFGWSLSEVLKKSRESKQKESLKDDTINGKDLADVEKKPTSEETQLDKDSKDDKVEKSAIELIIEGEEKLQEADDFIEIGTWSNDMADDIASFNQEDDDEDDAFHLPVLPANVKFCDQQTRYGSPTFWDVSNGESGFKGPKSSQNKQGGKGKAKGPAKPTFNYYDSDNSLGSSYDDDDNAGPLNYMHHNYSSDDDDVADDIDAGRIAFTSKNEAETIETAQEVEKRQKQLSIIQATNANERQYQQTKNLLIGFNFKHEDQKEPATIRYEESIAKLKTEIESGGMLVPHDQQLVLKRSDAAEAQVAKVSMMELLKQLLPYVNEDVLAKKLGDRRELLLSDLVELNADWVARHEQETYNVMGCGDSFDNYNDHHRLNLDEKQLKLQYERIEIEPPTSTKAITSAILPAGFSFDRQPD-LVGHPGPSPSIILQALTMSNANDGINLERLETIGDSFLKYAITTYLYITYENVHEGKLSHLRSKQVANLNLYRLGRRKRLGEYMIATKFEPHDN--WLPPCYYVPKELEKALIEAKIPTHHWKLADLLDIKNLSSVQICEMVREKADALGLEQNGGAQNGQLDDSNDSCNDFSCFIPYNLVSQHSIPDKSIADCVEALIGAYLIECGPRGALLFMAWLGVRVLPITRQLD-----------GGNQEQRIPGSTKPN-------AENVVTVYGAWPTPRSPLLHFAPNATEELDQLLSGFEEFEESLGYKFRDRSYLLQAMTHASYTPNRLTDCYQRLEFLGDAVLDYLITRHLYEDPRQHSPGALTDLRSALVNNTIFASLAVRHGFHKFFRHLSPGLNDVIDRFVRIQQENGHCISEEYYLLS-EEECDDAEDVEVPKALGDVFESIAGAIFLDSNMSLDVVWHVYSNMMSPEIEQFSNSVPKSPIRELLELEPETAKFGKPEKLADGRRVRVTVDVFCKGTFRGIGRNYRIAKCTAAKCALRQLKKQGLIAKKD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: * :: :* .::***.:***** :* ::***:**. *.* ***: * :**: : * :.: :*:* .. :: * :.* . : . : . :* :: * :*:. * **.::*:*:::** : : * ::: : *: ******:..: .. *: :*. : .**: : . ***:*:*.: ** *:* * :::*. : : . * * *: .*: * . : *... . :::.. .** :****:::.* : : :* : .* : : :..* * ::::***. * . . :: :*** :**: *: :** * * . ::* : .:*. .. * :. . * *.. :* ..* *. **.:*: ::.:** ** .*: * .::**:* :: .:: *.: :.. .. *: * *.*:*****::** *: *:**.**::***:*:********:* ** ******.******. : :::*. :. * : .:: *: **::* .**:: .: : : . :..* :.. *. * :.:**. :*:********.**:*:. : . . : ** *******: :.* * **.: .** .* :**:*****::* *:*** .: * **: .**: ..:.. ***:***** * *.. : . * . *****.* :.* *:*:* * * **:*****: : *****:* **::. *.::******.:*:** *. . *: : : :. : :* *:::***:* : *.* ::.. ::* : :. .:*::*:* *: . : . .. :: . *. : :****::* *** ***: ****:: ..*:*** **. :*.** .** .**.* : * .**********:***:****::*:** *** ** *.::** *.*::*********::**:******.*****.****:: ** *:::* *.: * *:* : : **.:* *****. * * * * . . :. * : :: : * . .. : *: . :. * . ..*: . : . * . . : : :. .. * . :. :*. . . . : : : .. . * .* ***::: : : ::: : : * : .*: :* ** *** :* : *.** * .:::* :.: .:*:. : :* * * . :: : : .. ::.. . : *. . :. : *.: :*.. : *. : :* * . :: . : .* * . ** * .** * .: . .*: : *:* *.: *: . *.*:* :::.*.***********:*.** .** *.* **:. **::*** :: . ** * . :. *:* . *::*:*** **..:.* *::::*****:***** * :*************:******:************.*******************::.:**:*: :** * .*** **::* *:.. . : * **: :. **:*****:**:***:****::**.***:.**:** ** * **:** .**:**:*****:*******. .*: ** :*****:*. **.*:*:**.*****.:**: ***.** : . :.", "identical_positions": 631, "similar_positions": 572, "identity": "27.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3497", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PT87-1", "uniprot_id": "MYLK3_RAT", "id": "E9PT87-1", "name": "Myosin light chain kinase 3", "aln": "MSGVSEEDPEGLGPQGLPALGGACLVTVDK-KLNVLTEKVDRLLHFQEDVTEKLQCVCQGMDHLEQGLHRLEASQELGLAGPGSTSPAAAQAAWPEVLELVRAVRQEGAQHGARLEALFKMVVAVDRAITLVGSTIQNSKVDDFILQGTVPWRKGSLADGPEENKEQAEVAGVKPKHVLNTGSVQAATSRALWEESQKQDTPVGTVEGLPLIIDTSLKGADLTQAGASLRQGVEALD-----PGQEPPPTEAESRLPALASEDTGTTLELSVAIDRISEVLTSLRMSQSAGEGTSSSKPDC----------SEPGPQPLGP--LTTDS-DIHSD-EGLPRISVRMREMTTPEELFETQGGSP-------IGSAEAPG-------------PGTVLEDQIPKGARPFPPLPKRSCNNGGASAEEATGPGAEPIRGPSLVTRDWRDEPVGTTDLQQGRDPGAVSPEPGKDHAAQGPGRTEAGRRVSSAAEAAIVVLDDSAAPPAPFEHRVVSIKDTLISTSYTVSQHEVLGGGRFGQVHRCTERSTGLALAAKIIKVKNIKDREDVKNEINIMNQLSHVNLIQLYDAFESKNSFTLIMEYVDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVSQTGHQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADTFKGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWLNHLIAKASGSNVRLRSQLLLQKY-MAQRKWKKHFHVVTAVNRLRKFPTCP------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UIZ8-1", "uniprot_id": "MYLK3_MOUSE", "id": "Q3UIZ8-1", "name": "Myosin light chain kinase 3", "aln": "MSGVSEEDPEGLAPQGLPALGGACLATMDK-KLNVLTEKVDRLLHFQEDVTEKLQCVCQGMDHLEQDLHRLEASRELSLAGSGSTPPTTAQAAWPEVLELVRAVRQEGAQHGARLEALFKMVVAVDRAITLVGSTFQNSKVADFIMQGTVPGRKGSLADGPEENKEQAEVAGVKPNHVLTTGGVQADASRTLWEESQKEDIPVRTVEGLPLIINTSLKGADLTQAGASLRQGVEVLG-----PGQVPLPTEAESRLPETASENTGATLELSVAIDRISEVLTSLKMSQGGGQETSSSKPDCWLSEEAMRLSSGPLPQPLGP--LTPDS-DIHSG-DALPRIPINMQEMATPGELLETQSGSP-------IGSAEAPG-------------LGTVLEDQIPKGARPFPPLPKRSSNNGGMSAEEEIGSGAEPMRGPSLATRDWRDETVGTTDLQQGIDPGAVSPEPGKDHAAQGPGRTEAG-RLSSAAEAAIVVLDDSAAPPAPFEHRVVSIKDTLISAGYTVSQHEVLGGGRFGQVHRCTERSTGLALAAKIIKVKNVKDREDVKNEVNIMNQLSHVNLIQLYDAFESKSSFTLIMEYVDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVSQTGHQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADTFKGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWLSHLPAKASGSNVRLRSQQLLQKY-MAQSKWKKHFHVVTAVNRLRKFPTCP------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q32MK0-3", "uniprot_id": "MYLK3_HUMAN", "id": "Q32MK0-3", "name": "Myosin light chain kinase 3", "aln": "MSGTSKES---LGHGGLPGLGKTCLTTMDT-KLNMLNEKVDQLLHFQEDVTEKLQSMCRDMGHLERGLHRLEASRAPGPGGADGVPHIDTQAGWPEVLELVRAMQQDAAQHGARLEALFRMVAAVDRAIALVGATFQKSKVADFLMQGRVPWRRGSPGDSPEENKERVEEEGGKPKHVLSTSGVQSDA-REPGEESQKADVLEGTAERLPPIRASGLG-ADPAQAVVSPGQGDGVPGPAQAFPGHLPLPTKVEAKAPETPSENLRTGLELAPAPGRVNVVSPSLEVAPGAGQGASSSRPDPEPLEEGTRLTPGPGPQCPGPPGLPAQARATHSGGETPPRISIHIQEMDTPGEMLMTGRGSLGPTLTTEAPAAAQPGKQGPPGTGRCLQAPGTEPGEQTPEGARELSPLQE-SSSPGGVKAEEEQRAGAEPGTRPSLARSDDNDHEVGALGLQQGKSPGAGNPEPEQDCAARAPVRAEAVRRMPPGAEAGSVVLDDSPAPPAPFEHRVVSVKETSISAGYEVCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDREDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWLNNLPAKASRSKTRLKSQLLLQKY-IAQRKWKKHFYVVTAANRLRKFPTSP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8C984-1", "uniprot_id": "MYLK3_DANRE", "id": "A8C984-1", "name": "Myosin light chain kinase 3", "aln": "-MGTSLYRSTLLSTGGFSVSDYIRKFTKNKPDVNNIQPNVG-FCHQSTQTSQQVKEVIS----AELELQQPEVTLP---NDPSSQHSPEAHTGASEPLKPVSAGESS---------------KALQKAKEISVKSSEPTHVQTFAPA--VHLEQIDVHNVPKQETNSLVAAPADAKCVIET------------MTKVEKDIALQQERALERADDSHVANKVFLKSIIPGQQLEKIED-----PQQQ---AEVSLFVDEDSLEKSVPGQHLDKKMEVLQKQAKDLPVVDEDSLNLSAP----------------------GQRQLEEKVDVPEKAEKKIDEAHKKMEEVPRKDELCIEK------------PVIRHAG---------------IKTQHEETMGMETTVPKHDESKCPTETYVEKTENKNAD-------VTLESDKIMICAVSPQN-------TSLDEDEKSKAAPLR---------KVESTLLIIDDSPPLPAPFDHRIVSAKQVPINSYYAVNPVEVLGGGRFGQVHKCAELSSGLTLAAKIIKVRGMKERDEVKNEIGVMNQLNHVNLIQLYDAFESRTNLTLIMEYVEGGELFERIIDESYQLTELDAIVFTRQICEGVQYLHQQYILHLDLKPENILCVNSTGNQIKIIDFGLARKYRPREKLKVNFGTPEFLAPEVVNYDFVSFPTDMWSVGVITYMLLSGLSPFMGDNDAETMNNILHAKWEFDTEAFENVSEEAKDFISSLLVSAKCSRLSASGCMKHSWLNNLEDKAKMYKVRLKSQMMLQRYLVAHRQWKKHFYAVAAANRLKRFQQSRSISTPN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.* *. *:. . * :. .:* : :*. : * . :.::::: : * *:: *.: .... :::. .* *: * * ... *:::* : : : ::* * * .: . : *:::.: ..: *: * . : * . * : : :: . * . * : ::.. . *. . .* :. .* : . *:. * * . .. . . .:.*: *: .* .: . * . * . * .*: .*: . : . : : . *: .. .: : .* * .*: :::***.. ****:**:** *:. *.: * * ************:*:* *:**.********:. *:*::****:.:****.*************: . **:****:*****:** **.*:*****.::*********:****:***************..**:***********:*:**********************:*************************:*:.****** *::..*:**:::*:.:*******:* ***. *..*:**: *:**.**.:* **. :.**:** :**:* :*: :*****:.*:*.***::* . ", "identical_positions": 272, "similar_positions": 202, "identity": "32.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3507", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61183-1", "uniprot_id": "PAPOA_MOUSE", "id": "Q61183-1", "name": "Poly(A) polymerase alpha", "aln": "--MPFPVTTQGSQQTQ------PPQRHYGITSPISLAAPKETDCLLTQKLIETLKPFGVFEEEEELQRRILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNILGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSKLFEAPNFFQKYKHYIVLLASAP-TEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQSFPAPK--------ESPDREE----------------FRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFELDMKIAAMHVKRKQLHQLLPSHVLQK-RKKHSTE----------------------------------------GVKLTALNDSSLDLSMDSDNSMSVPSPTSAMKTSPLNSSGSSQGRNSPAPAVTAAS-VTSIQASEVSVPQANSSESPGGPSSESIPQTATQPAISPPPKP--------------TVSRVVSSTRLVNPSPRPSG------NTATKVPNPIVGVKRTSSPNKEESPKKTKTEEDET-SEDANCLALSGHDKTETKEQVDLETSAVQSETVPASASLLASQKTSSTDLSDIPALPANPIPVIKNSIKLRLNR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G751-1", "uniprot_id": "A0A8I6G751_RAT", "id": "A0A8I6G751-1", "name": "Poly(A) polymerase", "aln": "--MPFPVTTQGSQQTQ------PPQRHYGITSPISLAAPKETDCLLTQKLIETLKPFGVFEEEEELQRRILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNILGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSKLFEAPNFFQKYKHYIVLLASAP-TEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQSFPAPK--------ESPDREE----------------FRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFELDMKIAAMHVKRKQLHQLLPSHVLQK-RKKHSTE----------------------------------------GVKLAALNDSSLDLSMDSDNSMSVPSPTSAMKTSPLNSSGSSQGRNSPAPAVTAAS-VTSIQASEVSVPQANSSESPGGPSSESIPQTATQPAISPPPKP--------------TVSRVVSSTRLVNPSPRPSG------NAATKVPNPIVGVKRTSSPHKEESPKKTKTEEDET-SEDANCLALSGHDKTETKEQVGMETSAAPSEAAPASASLVASQKTSSTDLSDIPALPANPIPVIKNSIKLRLNR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51003-1", "uniprot_id": "PAPOA_HUMAN", "id": "P51003-1", "name": "Poly(A) polymerase alpha", "aln": "--MPFPVTTQGSQQTQ------PPQKHYGITSPISLAAPKETDCVLTQKLIETLKPFGVFEEEEELQRRILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKRHNIYSNILGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVFSKWEWPNPVLLKQPEECNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILLSKAEWSKLFEAPNFFQKYKHYIVLLASAP-TEKQRLEWVGLVESKIRILVGSLEKNEFITLAHVNPQSFPAPK--------ENPDKEE----------------FRTMWVIGLVFKKTENSENLSVDLTYDIQSFTDTVYRQAINSKMFEVDMKIAAMHVKRKQLHQLLPNHVLQK-KKKHSTE----------------------------------------GVKLTALNDSSLDLSMDSDNSMSVPSPTSATKTSPLNSSGSSQGRNSPAPAVTAAS-VTNIQATEVSVPQVNSSESSGGTSSESIPQTATQPAISPPPKP--------------TVSRVVSSTRLVNPPPRSSGNAATSGNAATKIPTPIVGVKRTSSPHKEESPKKTKTEEDET-SEDANCLALSGHDKTEAKEQLDTETSTTQSETIQTAASLLASQKTSSTDLSDIPALPANPIPVIKNSIKLRLNR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WVP6-1", "uniprot_id": "PAPOB_MOUSE", "id": "Q9WVP6-1", "name": "Poly(A) polymerase beta", "aln": "-MMPFAVTTQGAQQPA------PAPKQFGISSPISLAAPKDTDRELTQKLIETLQPFGVFEEEEELQRRILILQKLNNLVKEWIREISESRNLPQAVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVDRNDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDSFRLTLRAIKLWAKCHNIYSNILGFLGGVSWAMLVARTCQLYPNAIASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMIEEFKQGLAITHEILLNKAEWSKLFEAPSFFQKYKHYIVLLASAP-TEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQSFPAPK--------ETADKEE----------------FRTMWVIGLVLKKPENSEILSIDLTYDIQSFTDTVYRQAINSKMFEMDMKIAAMHLRRKELHQLLPNHVLQK-KETHLTE----------------------------------------SVRLTAVTDSSLLLSIDSENSMTAPSPTGTMKTGPLT--GNPQGRNSPALAVMAAS-VTNIQFPDVSLQHVNPIESSGIALSESIPQIPSQPTISPPPKP--------------TMTRVVSSTHLVNHPSRPSG------NTATNIPNPILGV---------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRJ5-1", "uniprot_id": "PAPOB_HUMAN", "id": "Q9NRJ5-1", "name": "Poly(A) polymerase beta", "aln": "-MMPFPVTTQGPPQPA------PPPNRYGVSSPISLAVPKETDCLLTQRLIETLRPFGVFEEEEELQRRILVLEKLNNLVKEWIREISESKSLPQSVIENVGGKIFTFGSYRLGVHTKGADIDALCVAPSHVDRSDFFTSFYAKLKLQEEVKDLRAVEEAFVPVIKLCFDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNIDNFRLTLRAIKLWAKCHNIYSNILGFLGGVSWAMLVARTCQLYPNAVASTLVRKFFLVFSEWEWPNPVLLKEPEERNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSISTRMVMIEEFKQGLAITHEILLSKAEWSKLFEAPSFFQKYKHYIVLLASAS-TEKQHLEWVGLVESKIRILVGSLEKNEFITLAHVNPQSFPAPK--------ENPDMEE----------------FRTMWVIGLGLKKPDNSEILSIDLTYDIQSFTDTVYRQAVNSKMFEMGMKITAMHLRRKELHQLLPHHVLQD-KKAHSTE----------------------------------------GRRLTDLNDSSFDLSAGCENSMSVPSSTSTMKTGPLIS--SSQGRNSPALAVMTAS-VANIQATEFSLQQVNTNESSGVALNESIPHAVSQPAISPSPKA--------------MVARVVSSTCLISHPDLQET---------QQQTYLIL-----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B770-1", "uniprot_id": "A0A8M2B770_DANRE", "id": "A0A8M2B770-1", "name": "Poly(A) polymerase", "aln": "--MPFPITSQ-VQTAQ------PTPKHYGITSPISLAPPKEADLVLTRKLTETLRPFGVFEEELELQRRILVLGKLNTLVKFWIREVSEAKNIPASVIDSVGGKIFTFGSYRLGVHTKGADIDALCVAPRHVERTDFFSSFYEKLKEQEEVKDLRAVEEAFVPVIKLAFDGIEIDILFARLALQTIPENLDLRDDGLLKNLDIRCIRSLNGCRVTDEILHLVPNIENFRLTLRAIKLWAKRHNIYSNILGFLGGVSWAMLVARTCQLYPNAVAATLVHKFFLVFSKWEWPNPVLLKQPEDCNLNLPVWDPRVTPSDRYHLMPIITPAYPQQNSTYNVSASTRAIMVEEFKRGLAITDEILQNKADWSKLFEAPNFFQKYKHYIVLLASAQ-TEKQHLEWVGLVESKIRILVGNLEKNEFITLAHVNPQSFPGPK--------EGNDKEE----------------FSTMWVIGIVFKKMEGSENLNVDLTFDIQSFTDTVYRQAITSKMFEQDMKITAMHVKRKQLHQLLPEVAIHRSKRKHSSD----------------------------------------GVR--AMNDSNLDLSLDSDNSMSVPSPTGPS-AAKIARAPSPQGSTGTATNTSELQGKTEATGENTHLASVDGTSSSNASGKEAAPPQSTSP-IQSEKKP--------------SEQNPLPSPCLSAEPAVKRP--------ASALENEMTKKAKVEDLSAPEAKSSGETDGHVAPAQIVEVIPSDGELKTETELMVEDTAEKVP-----------LAQKTSNADLSDVPVLPNNPIPVVKNSIKLRLSR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KG96-1", "uniprot_id": "A0A0B4KG96_DROME", "id": "A0A0B4KG96-1", "name": "polynucleotide adenylyltransferase", "aln": "MWNSEPTHRQHHQHNGNSTSGGPPAKQLGMTSAISLAEPRPEDLQRTDELRGSLEPYNVFESQDELNHRMEILAKLNTLVKQWVKEISVSKNMPESAAEKLGGKIYTFGSYRLGVHHKGADIDALCVAPRNIERTDYFQSFFEVLKKQPEVTECRSVEEAFVPVIKMNFDGIEIDLLFARLSLKEIPDDFDLRDDNLLRNLDHRSVRSLNGCRVTDEILALVPNIENFRLALRTIKLWAKKHGIYSNSLGYFGGVTWAMLVARTCQLYPNAAAATLVHKFFLVFSRWKWPNPVLLKHPDNVNLRFQVWDPRVNASDRYHLMPIITPAYPQQNSTFNVSESTKKVILTEFNRGMNITDEIMLGRIPWERLFEAPSFFYRYRHFIVLLVNSQ-TADDHLEWCGLVESKVRLLIGNLERNPHIALAHVNPKCFEFKKGQSANNSQNNSGNEDDLKQSQGNQSAVTSAPFCSMWFIGLEFER---SENLNVDLTESIQNFTEHVMMHGVNIKMLKEGMTIDARHVKRKQLSLYLDSDFLKRERKSMESHNNFNNTLLANRKRLSTELAQSQDPLPPGQQPSSGNRGRDSGAKIQRLSDSLTEENSNASSDMGAGTPTTPTTAQLSAPSFKSSGKNGSEIDVVEQEPTQPHNNGNASSNTTTTEVACSXQPPTLHPHPPHQQPPPAPPQPPAHHHHHQKFRKNNNAAAAAASNSIFNQRSILHA------ASSLSAALSITGHKRKQQTATSTTMISSSNIAHSNYTQHSTHNNNGGGGGSHYNKTYYIDDDDEDNNQPLLTPNNQTQQQQKAVRITATSASPATSVPVAASAAPPAPTISL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P29468-1", "uniprot_id": "PAP_YEAST", "id": "P29468-1", "name": "Poly(A) polymerase", "aln": "---------------------MSSQKVFGITGPVSTVGATAAENKLNDSLIQELKKEGSFETEQETANRVQVLKILQELAQRFVYEVSKKKNMSDGMARDAGGKIFTYGSYRLGVHGPGSDIDTLVVVPKHVTREDFFTVFDSLLRERKELDEIAPVPDAFVPIIKIKFSGISIDLICARLDQPQVPLSLTLSDKNLLRNLDEKDLRALNGTRVTDEILELVPKPNVFRIALRAIKLWAQRRAVYANIFGFPGGVAWAMLVARICQLYPNACSAVILNRFFIILSEWNWPQPVILKPIEDGPLQVRVWNPKIYAQDRSHRMPVITPAYPSMCATHNITESTKKVILQEFVRGVQITNDIFSNKKSWANLFEKNDFFFRYKFYLEITAYTRGSDEQHLKWSGLVESKVRLLVMKLEVLAGIKIAHPFTKPFESSY---------CCPTED--------------------------------------DYEMIQDKYGSHKTETALNALKLVTDENKEEESIKDAPKAYLSTMYIGLDFNIENKKE----------------------------------------KVDIHIPCTEFVNLCRSFNEDYGDHKVFNLALRFVKGYDLPDEVFDENEKRPSKKSKRKNLDARHETVKRSKSDAASGDNINGTTAAVDVN-----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . *::..:* . . : . * *. . ** : * .*: :* *: *.: :: *:* :.:. . . ****:*:******** *:***:* *.* :: * *:* * *: : *: : .* :****:**: *.**.**:: *** :* .: * *..**:*** : :*:*** ******* ***: : **::**:*****: : :*:* :*: ***:******* ******* ::.::.:**:::*.*:**:**:** :: *.. **:*:: ..** * **:******. :*.*:: **: ::: ** :*: **.:*: .: * .*** .** :*:.:: : . : : .::*:* ******:*:*: .** * :** .: * *: * :.: . .:. : . . :: . .. . . ... . . . . : . . . ", "identical_positions": 165, "similar_positions": 162, "identity": "19.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3509", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI46-1", "uniprot_id": "PAAT_RAT", "id": "Q5XI46-1", "name": "ATPase PAAT", "aln": "METAIEDAGLDRGPTLTSSWDAACGALTQSLFLTRTGPRAQDLDFEQLLAPPAQGPDLVSLKSSLSPRDENPCFIYLKCGPNGGEEILSVGILSSARNMEVY-LGEEYCGTSRGKNVCTVLDN--SEHEKILLYKKYLKLESPTHACKIKLLSFGEEQCVLISKVVVHLRPRSAKPSPSSPALGSRIDLDNIQTIMESMGSKLSPGAQQLMDMIRFQQQNCLPIRDQLQSVLGTAGHKHLMALQSSPSSGVVDKASSTPFPFRTGLTPSAITENLKALIDKSTQPSGEGNTTNHNECHLMPQNHS-LESDLKNAVSSFLPKKASGSSSVPNSELLPFLQNLCSQVNHLRVGHNARWQENVSKPREGTVGVPLEEQPVCSYLEKILSKNMEVMEKKLMKHIDERIYQLQEHIDAKMALLVDLLRSPNSPSPGMPLRHYDSRERLSNGER", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D2Q3-1", "uniprot_id": "PAAT_MOUSE", "id": "Q9D2Q3-1", "name": "ATPase PAAT", "aln": "METAIEDAGLDRGPTLTSSWDAACGALTQSLFLTRTGPRAQDLDFEQLLEPPAPSQDPVSLKSSLSPRDENPCFIYLNCGPNGGEEILSVGVLSSARNMEVY-LGEEYCGTSRGKTACTVLDD--SEHEKILLYKKYLKLDSPTHACKIKLLSFGEKQCVLVSKVVVHLRPRSADPSPRSAALGSRIDLDNIQTIMESMGSRLSPGAQQLMSMIRFQQQNRLPIGDQLQSVLGSAGHKHLMALQSSPSPAVLDKASSTPFPFRTGLTPSAITENLKALIDKSAQPSGEGNTTNHDEGHLMPQNHS-LESDLKNAVSSFLPKKASGSSSVPSSELLPFLQNLCSQVNHLRVGHNARWQENISKPREGMVGVPMEEQPVCSYLEKILSKNMELMEKKLMDHIDERIYQLQEHIDAKMALLVDLLRGPNSPPPGMPLRHYDSRERLSNGER", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H8K7-1", "uniprot_id": "PAAT_HUMAN", "id": "Q9H8K7-1", "name": "ATPase PAAT", "aln": "METRTEDGGLTRRPTLASSWDVAGGALTHSLLLTRAGLGPGDFDWEELLAPPAPGQDLVILKRNHNNKDENPCFLYLRCGPDGGEEIASIGILSSARNMEVY-LGEEYCGTSRGKNVCTVLDD--SEHEKIILYKKNLKLESSTHACKIKLLSFGERQCVFISKVVVHMRSVFANSSTSSPALGSRIDLDKVQTIMESMGSKLSPGAQQLMDMVRCQQRNCIPIGEQLQSVLGNSGYKHMIGLQSSSTLGTLNKSSSTPFPFRTGLTSGNVTENLQTYIDKSTQLPGGENSTKLDECKVMPQNHSFLENDLKNAMASFLPKKVSDNSNIPNSELLPFLQNLCSQVNHLHVGNKTECQENITKHGERILGVGMEEQSICSYLEKILSKNMELMEKKLMDYIDQRIHELQEHIDDKIALLLDLLQNPNSPPTGIPLRHYDSGERLSNGER", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GXA3-1", "uniprot_id": "A0AC58GXA3_DANRE", "id": "A0AC58GXA3-1", "name": "", "aln": "-MFSSKDGLISAN----SSWPCSSQKQLSDVLSTTLDNKLNDTQWFQHDR-----NEAVCLER---AEEDSPCVVTLQCSPGSASAISSLQVVSEARTIEVYSLSGEYCGTCRGEEVQISHTNGYISEEERHFYRNNLILESPAVSCEVKLLSLGGRSSVSVAHVCVGLETLKGRQG--GPRVEPGIDLQQVQAMMEEMGTTLSPGAQNLLELVQCQQKNKSDMLNGFIPLLMGGGALSCLSRGGGASSAEEAESG------------PNLPSGLEQLLSASNQ----------------------------NQIPTAMSALLNSESATVSPDLLPMLQSVCGQVTQLRLEEATSPERKKNGEREGHICCGGFEK----ILETVVEKRMDEMERRLKEHLDLRLDALQQRLEITLQQALSHKQQQ-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. : *** : .:: * . * :: : : * *: .::.**.: *.*.*.... * *: ::*.**.:*** *. *****.**: . : ..*: :*:: * *:*.: :*::****:* ...* :::* * :.. . . .. : . ***:::*::**.**: ******:*:.::: **:* : : : .:* .* :. ...: . ::. :...*: :. * * * :.: :. ...* ..:***:**.:*.**.:*:: . : :.: . * : *: **.::.*.*: **::* .::* *: **:::: .: :. : ", "identical_positions": 90, "similar_positions": 149, "identity": "20.09%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3511", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q16849-1", "uniprot_id": "PTPRN_HUMAN", "id": "Q16849-1", "name": "Receptor-type tyrosine-protein phosphatase-like N", "aln": "MRRPRRPGGLGGSGG---LRLLLCLLLLSSRPGGCSAVSAHGCLFDRRLCSHLEVCIQDGLFGQCQVGVGQARPLLQVTSPVLQRLQGVLRQLMSQGLSWHDDLTQYVISQEMERIPRLRPPEPRPRDRSGLAPKRPGPAGELLLQDIPTGSAPAAQHRLPQPPVGKGGAGASSSLSPLQAELLPPLLEHLLLPPQPPHPSLSYEPALLQPYLFHQFGSRDGSRVSEGSPGMVSVGPLPKAEAPALFSRTASKGIFGDHPGHSYGDLPGPSPAQLFQDSGLLYLAQELPAPSRARVPRLPEQGSSSRAEDSPEGYEKEGLGDRGEKPASP------AVQPDAALQRLAAVLAGYGVELRQLTPEQLSTLLTLLQLLPKGAGRNPG-GVVNVG-ADIKKTMEGPVEGRDTAELPARTSPMPGHPTASPTSSEVQQVPSPVSSEPPKAARPP-VTPVLLEKKSPLGQSQPTVAGQPSARPAAEEYGYIVTDQKPLSLAAGVKLLEILAEHVHMSSGSFINISVVGPALTFRIRHNEQNLSLADVTQQAGLVKSELEAQTGLQILQTGVGQREEAAAVLPQTAHSTSPMRSVLLTLVALAGVAGLLVALAVALCVRQHARQQDKERLAALGPEGAHGDTTFEYQDLCRQHMATKSLFNRAE----GPPEPSRVSSVSSQFSDAAQASPSSHSSTPSWCEEPAQANMDISTGHMILAYMEDHLRNRDRLAKEWQALCAYQAEPNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWPDEGASLYHVYEVNLVSEHIWCEDFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRGRSCPIIVHCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEVNAILKALPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60673-1", "uniprot_id": "PTPRN_MOUSE", "id": "Q60673-1", "name": "Receptor-type tyrosine-protein phosphatase-like N", "aln": "MRRPRRPGGSGGSGGSGGLRLLVCLLLLSGRPGGCSAISAHGCLFDRRLCSHLEVCIQDGLFGQCQAGVGQARPLLQVTSPVLQRLQGVLRQLMSQGLSWHDDLTQHVISQEMERIPRLRPPEPHPRDRSGLVPRKPGPAGELLTQGNPTGSSPAAQG-FPRPAGGRSWGGS--PLSSLQAELLPPLLEHLLMPPQPPHPALTYEPALLQPYLFHQFGSRDGSRGSESSSGVVGVGHLSKAEGPALFSRSASKAILGTHSGHSFGDLTGPSPAQLFQDSGLLYMAQELPVPGRARAPRLPENGGN-RAEDSSEGHEEEVLGGRGEKSPPQ------AAQPELSLQRLTAVLAGYGVELRQLTPEQFSTLLTLLQLLPKGTGRNLE-GAVNVGGADVKKTIQQMQRG-DPAEALPPTPSLPGYLTASPASSEVQQVLSPGFPEPPHTPSPLGSSSVLLEKKSPLGQSQPTVVGRPSARPSAEEYGYIVTDQKPLSLVAGVRLLEILAEHVHMSSGSFINISVVGPAVTFRIRHNEQNLSLADVTQQAGLVKSELEAQTGLQILQTGVGQREEAAEVLPRQAHGISPMRSVLLTLVALAGVAGLLVALAVALCMRHHSRQRDKERLAALGPEGAHGDTTFEYQDLCRQHMATKSLFNRAE----GQPEPSRVSSVSSQFSDAAQASPSSHSSTPSWCEEPAQANMDISTGHMILAYMEDHLRNRDRLAKEWQALCAYQAEPNTCAAAQDESNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWPDEGSSLYHVYEVNLVSEHIWCEDFLVRSFYLKNLQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRGRSCPIIVHCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEVNAILKALPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1R8X1-1", "uniprot_id": "F1R8X1_DANRE", "id": "F1R8X1-1", "name": "", "aln": "MMHPR-------------VWRALFLISVFCQLG---MTGKYGCLFEKRLCSREQFCSDDKIFGQCRSSR-HDQVQYQVSVPVLQRLQQVLKELMLQGFSWQDEITQQIIAKELSRIP-------HTRTQKSQNAQPPPPAAKKVYSSPNSEPGPAQSY-----------------------------VDYMVLDPHQSSP-LRMQTVPVDPYSYLQEG----------------MTHSLHPHASMGYQRPSSR----------SGSQQRERDRQLLQDAVSLYLSSAQPSFRHRGAAALPAAPYYEDLDFPLEYGEDYTLHEQRTNKKPPQDYSSVAGLDDDTLTQLGSLLKGFGVDPRDLSPQQIKRLTLVLQLLQNMEKTDQSPGTVTVKETIVAGSDKVTENG---GKSPSTISALPSAPTHQQAP---TQPPSTSTPAPVTVPAEPTLSAKDLDLKEKTANILKTTKDGTNTR---EEYGYIVTNQSHLSLYDGVKLLETLAERIHLSTSSFINISVVGSALTFRIRQNALNLSAEDVANKAVAEKNFLEGETGLKIIQTGVGERSEGRG-LPQATRIGEGSRGVVLTMVAMACVGTVLLVALAVACLRHHARQLASGKLG-LGPEAG-AETHFDYQELCRQHMAAKSSFTRPEPGGRRGTDTSRVSSVSSQFSDGPQHSPSSHSSTPSWSEEPAQSNMDISTGHMILAYMEDHLKNKDRLQKEWEALCSYQAEPSSVSVAQCESNMEKNRYPDFVPYDHSRVKLKAEVNPSKGDYINASTIIDHDPRLPAYIATQGPLPHTVADFWQMVWENGCTVIVMMTALVEDGEKQCERYWPDEGSSLYNIYEVNLVSEHIWCKDFLVRSFYLKNVQTQETRTLTQFHLLSWPANGIPSSTRPLLDFRRKVNKCYRGRSCPIIVHCSNGTGRTGTYILIDMVLNRMAKGVKEIDIAATLEHIRDQRPSMVRTKDQFEFALTAVAEEVNAILKALPQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :** : : *: : : * . :****::****: :.* :* :****: . : : **: ******* **::** **:**:*::** :*::*:.*** :.* :.. .: * **.: : .. : ..** . :::::: *: . * * :.. ::** : * * : :.... :.*.:*: *. **:**: **::. * : .. ** : . * *. * : : . * : :* :* ::* *:**: *:*:*:*:. * :**** : : *.*.* : : : : .* .: . ..:*. * . :. * *. . * .. :. *: *. .: *. . ..:* ********:*. *** **:*** ***::*:*:.*********.*:*****:* *** **:::* *. **.:***:*:*****:*.*. **: :: . *.*:**:**:* *. :*:. .. *:*:*:** . :*. ****.. .:* *:**:*******:** *.*.* .:.************..* ***********.*****:******************:*:*** ***:***:*****.: :.** *.*::***:***:****:*:***.* .**:.******.**:****:**********.**:*********.*******:*.***** ***:*******:***::************:***********:************:*****:* *:****************************:*:*******************************:*****.:**:************************", "identical_positions": 471, "similar_positions": 234, "identity": "47.34%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3513", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LN54-1", "uniprot_id": "A0ABK0LN54_RAT", "id": "A0ABK0LN54-1", "name": "Methenyltetrahydrofolate synthase domain-containing protein", "aln": "--MRLTSSVRRQALREASLGDVLVMEARAGDVSKQSIRERIWDYMESHNIADFPRPVHHRIPNFKGASRAAEHFPHLHAFSAARTIKVNPDAPQRNARFLVLESRKTLLVPTPRLRTGLFNKIIPPPGATKDILRKCATSQGVRNFSVPVGLDSNVLVDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVHEGTLVVTIVHDCQVVD-IPEALLEDHDLTVDYILTPTRVIATGCARPKPTGILWSKVSCEMLTKIPVLRSLREREKRAGTDVTLQ------AEPGNTQQPAPSTVRRPQ-------------DRPQSQPAPSTVRRPQDRPQSQAGFRGRSHSSLEGTDTHLAAT-----------------------VCLGNLPYSARVRELKRALQELGAVPLRLTWQGPQHRAILHYTDSAAAQQAASLLQGLRLGDNALRVSLG-QQRDT-------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3URQ7-1", "uniprot_id": "MTHSD_MOUSE", "id": "Q3URQ7-1", "name": "Methenyltetrahydrofolate synthase domain-containing protein", "aln": "------------------------METQEG-VSKQSIRERIWDYMESHDIADFPRPVHHRIPNFKGAAQAAGHLPHLQAFHVARTIKVNPDAPQRNARFLVLESKKTLLVPTPRLRTGLFNKITPPPGATKDILRKCATSQGVRNFSVPVGLDSSVLVDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVHKGTPVVTIVHDCQVVD-IPEALVEDHDLTVDYILTPTRVITTGCARPKPTGIMWSKVSCEMLTKIPVLRNLREREKQAGKDVTLR------DEPG-SQQPAPGPIRRPQ-------------DRPQ------------------TGSRGGSRSPLQGADTQLAAT-----------------------VCVGNLPFTTRVRELKRVLQELGVVPLRLTWQGPQHRAVLHYTDSAAAQQAASLLQGLRLGANALRVSLG-QQRDM-------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2M296-1", "uniprot_id": "MTHSD_HUMAN", "id": "Q2M296-1", "name": "Methenyltetrahydrofolate synthase domain-containing protein", "aln": "------------------------MEPRAVGVSKQDIREQIWGYMESQNLADFPRPVHHRIPNFKGSYLACQNIKDLDVFARTQEVKVDPDKPLEGVRLLVLQSKKTLLVPTPRLRTGLFNKITPPPGATKDILRKCATSQGVRNYSVPIGLDSRVLVDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVSKETPVVTIVHDCQVVD-IPEELVEEHDITVDYILTPTRVIATGCKRPKPMGITWFKISLEMMEKIPILRSLRAREQQAGKDVTLQGEHQHLPEPGCQQTVPLSVGRRPP-------------DTPGPE----------------TNSMEAAPGSPPGEGAPLAAD-----------------------VYVGNLPGDARVSDLKRALRELGSVPLRLTWQGPRRRAFLHYPDSAAAQQAVSCLQGLRLGTDTLRVALARQQRDK-------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0P464-1", "uniprot_id": "MTHSD_DANRE", "id": "Q0P464-1", "name": "Methenyltetrahydrofolate synthase domain-containing protein", "aln": "---------------------MEPVIKINQGETKWDVRHKVWNYIEVKNLANFPRPVHNRIPNFKGALEACNKVAQLEIFIESAVVKVDPDKPMEGVRLAALKARKSLLVPTPRLRFGLFNRITPPKGATKETLRVCSTSQGIKEFSVPVGLDDKVQVDLVVVGSVAVSEKGYRIGKGEGFADMEYAMMACMGSVTESTWVITVVHDCQVMD-IPEELIERHDLMVDFIITATRVIKTECKHPKPQGIIWSMLHKEELKKIPILKKLRTLEQEAGKDVALK------LIHAGEDEYRKSKELQWQ-------------SHPKAD--------------LEFKCLASNSDRCSGFEPKFPTTT----------------------VYLSDIPPALRVSELKGLLREQEVVPLQIRWQGAKRKAFLLYADFTGAERATAILQKLFINGHTIQAKCVSSQKM--------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN21-1", "uniprot_id": "Q9VN21_DROME", "id": "Q9VN21-1", "name": "", "aln": "MEDQSNAAPAVAAENGGNTAQEVSSTTQPIEPTKRSLRVQTWKKIQEGKVGIGFNNIFNRIPSFVGADKAAALFANEEEFKKAQHIKVNIDRVLHEFKELALLADKSVYLPSTRESSALCLKVDVLADATEEQKKEALRVQDIQKFRSEIGLDSGLKLDIVVIGSVVVSREGYRIGRGNGFADLDIGLLIELGAITPKTIIVTIVHDMQVVDSLPPNLFQKYDTPVDIIATPTEIIRVPKRLSFPNGVYWELLSERRLKILPVLQQLKEREEKAGKSISLKEEDTDVEQHQNNRRRRGPVRRRIQRGNPGRTTSQTDNEQPQGETAQKRTPRRKGRFVNRRRRTTKSEGDQSGVEAGAKTDDRKLPEAGTDERRSKKNKNSDFCIKLTNLSRDIRVKDLKSELRKRECTPMSISWKGHFGKCFLHFGNRKGVPSTQDDMDKVLKSLNDLSLTITTGGETAPAAAAGEGGEKAESAETATPVQTKTILVNVELIQFGEKKSASSTGANAGAGEDGKADAQNGGEAVTVAGGDVGGARIEAVDTTTV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .:* : * :: .:. . :.:***.* *: *. . . . * : :**: * . : .* : *:: :*:.* .* :: .**:: : . *.:::: :***. : :*:**:***.**.:*:***:*:*:**:: .:: :*:: * ::*:*** **:* :* *.: :* ** * *.*.:* . . * *: * : . : :*:*:.*: *:.**..::*: : . * . * . : : : ::. ** :** *:: .*: : *:* :..* : : .. : :: : . . : . ", "identical_positions": 79, "similar_positions": 126, "identity": "14.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3522", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8J8XDG1-1", "uniprot_id": "A0A8J8XDG1_RAT", "id": "A0A8J8XDG1-1", "name": "E3 ubiquitin-protein ligase CHFR", "aln": "MEPHGEDEQPPPREPWGRLLRLGAEEDEPQILLWKREWTIGRRRGCDLSFPSNKLVSGDHCKLRVDEKSGEVTLEDTSTNGTVINKLRVVKKQTYPLQSGDIIYLVYRKNEPEHNVAYLYESLNGKQSLTQESLEANKENMFHVTKESSGP--GQGDDPQVPLLSPMAQTCLEEPQPSTSTSDLLPTASTSSTEPELTSAGQKHSSSSGPGTISISPKECSSLVANGELSSLSSVFQD-NEASFSLLKTEDTEELEPAKKKMKGDGELDLNLQLSVADQRGIAQTSSEDVKDASVKPDKMEETLTCIICQDLLHDCVSLQPCMHTFCAACYSGWMERSSLCPTCRCPVERICKNHILNNLVEAYLLQHPDKSRSEEDVRSMDARNKITQDMLQPKVRRSFSDEEGSSEDLLELSDVDSESSDISQPYIVCRQCPEYRRQAVQSLPCPVPESELGATQALGGEAPSTSASLTTAAPGYTCPLQGSHAICTCCFQPMPDRRAEHEQDSRIAPQQCAVCLQPFCHLYWGCTRTGCFGCLAPFCELNLGDKCLDGVLNNNNYESDILKNYLTTRGLTWKNMLTESLLALQRGVFILSDYRITGNTVLCYCCGLRSFRELTYQYRQNIPASELPVTVTSRPDCYWGRNCRTQVKAHHAMKFNHICEQTRFKN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q810L3-1", "uniprot_id": "CHFR_MOUSE", "id": "Q810L3-1", "name": "E3 ubiquitin-protein ligase CHFR", "aln": "MELHGEEQPPPPQEPWGRLLRLGAEEDEPQILLWKREWTIGRRRGCDLSFPSNKLVSGDHCKLTVDEISGEVTLEDTSTNGTVINKLQVVKKQTYPLQSGDIIYLVYRKNEPEHNVAYLYESLSGKQSLTQDSLEANKENMFHVTKDCSGP--GQGDDPQVPLLSPMAQTCLEEPQPSTSTSDLLPTASTSSTEPELTSAGQKHSSSSGPGNTSISPKGRSSLVANGELSSLSPVFQD-KEASFSLLESKDHEELEPAKKKMKGDGELDTNLQLLVSGQRGNAQTSSEDVKDASVKPDKMEETLTCIICQDLLHDCVSLQPCMHTFCAACYSGWMERSSLCPTCRCPVERICKNHILNNLVEAYLIQHPDKSRSEEDVRSMDARNKITQDMLQPKVRRSFSDEEGSSEDLLELSDVDSESSDISQPYIVCRQCPEYRRQAVQSLPCPVPESELGATLALGGEAPSTSASLPTAAPDYMCPLQGSHAICTCCFQPMPDRRAEREQDPRVAPQQCAVCLQPFCHLYWGCTRTGCFGCLAPFCELNLGDKCLDGVLNNNNYESDILKNYLATRGLTWKSVLTESLLALQRGVFMLSDYRITGNTVLCYCCGLRSFRELTYQYRQNIPASELPVTVTSRPDCYWGRNCRTQVKAHHAMKFNHICEQTRFKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EP1-1", "uniprot_id": "CHFR_HUMAN", "id": "Q96EP1-1", "name": "E3 ubiquitin-protein ligase CHFR", "aln": "MERPEEGKQSPPPQPWGRLLRLGAEEGEPHVLLRKREWTIGRRRGCDLSFPSNKLVSGDHCRIVVDEKSGQVTLEDTSTSGTVINKLKVVKKQTCPLQTGDVIYLVYRKNEPEHNVAYLYESLSEKQGMTQESFEANKENVFHGTKDTSGAGAGRGADPRVPPSSPATQVCFEEPQPSTSTSDLFPTASASSTEP--SPAGRERSSSCGSGGGGISPKGSGPSVASDEVSSFASALPDRKTASFSSLEPQDQEDLEPVKKKMRGDGDLDLNGQLLVAQPRRNAQTVHEDVRAAAGKPDKMEETLTCIICQDLLHDCVSLQPCMHTFCAACYSGWMERSSLCPTCRCPVERICKNHILNNLVEAYLIQHPDKSRSEEDVQSMDARNKITQDMLQPKVRRSFSDEEGSSEDLLELSDVDSESSDISQPYVVCRQCPEYRRQAAQPPHCPAPEGEPGAPQALG-DAPSTSVSLTTAVQDYVCPLQGSHALCTCCFQPMPDRRAEREQDPRVAPQQCAVCLQPFCHLYWGCTRTGCYGCLAPFCELNLGDKCLDGVLNNNSYESDILKNYLATRGLTWKNMLTESLVALQRGVFLLSDYRVTGDTVLCYCCGLRSFRELTYQYRQNIPASELPVAVTSRPDCYWGRNCRTQVKAHHAMKFNHICEQTRFKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5WW08-1", "uniprot_id": "CHFR_DANRE", "id": "A5WW08-1", "name": "E3 ubiquitin-protein ligase CHFR", "aln": "MTNQDSD------QAWGKLVKVDASPG-SEIVLINSECTVGRKKDCDLSFPANKLVSGNHCKITHDQNSGKVWLEDMSTNGTVINMSKVVKKQTHLLQNGDVIYFVYRKNEPEQNIAYVYQSITPQESASHDVEDAGREEDSDLTETESEP-----APVEPVIVKPLPQSGHEDPQPSTSSSSLHFYNMP--------------LSTCSDVSARKNPVSSSAVCKGDSTSSGSPAQTRLKWTCWTDGEPE--EEMQRKRRKTDRD-DPGFGSAHSDASADIPLRGASGKEKTEGATTDKMEESLTCIICQDLLYDCISVQPCMHTFCAACYSGWMERSSFCPTCRCPVERIRKNHILNNLVEAYLLQHPEKCRTEDDLRSMDARNKITQDMLQPKVERSFSDEEASSDYLFELSDNDSDISDMSQPYMMCRQCPGYRKELSSALWICESAQSESLAKTAGDGPSTSSDSTTAAPQEFRCPPQASHLICTCCLQPMPDRRFEHLP-PQVSPQHCLVCQKPFCHVYWGCPRIGCHGCLARFSELNLNDKCLDGVFNGNQYESEVLQNYLSCRGMSWRHLLQDSLQALQQGLYHLSDYRITANSFLCYCCGLRTFRELAYKYRERIPPSELPDAVTNRPNCYWGRNCRTQVKAHHALKFNHICEQTRFKN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . :.**:*:::.*. . ..::* : * *:**::.******:******:**:: *: **:* *** **.***** :****** **.**:**:********:*:**:*:*:. ::. ::: :*.:*: . *: * . . .* .* *:******:*.* . *:.. .* .. ... ** :.. : :.:: :.: *::: ::* * : . . : : . : . ..*****:**********:**:*:********************:*********** *************:***:*.*:*:*::*****************.*******.**: *:**** **: **:****::***** **:: .. . . . . : * ..::* * .:* : ** *.** :****:******* *: .:::**:* ** :****:****.* **.**** *.****.*******:*.*.***::*:***: **::*: :* :** ***:*:: *****:*.::.********:****:*:**:.**.**** :**.**:****************:*************", "identical_positions": 332, "similar_positions": 172, "identity": "49.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3527", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A4D7-1", "uniprot_id": "E2F7_RAT", "id": "D4A4D7-1", "name": "Transcription factor E2F7", "aln": "-MEVNCLTLKDLISPRQTRLDFAVEDAE--TAQKENIFVDRSRMTPKTPMKNEPIDLSKQRIFTPERSPITPVKLVDRQPQVEPWTPTANLKMLISAASPDIRDREKKKELFRPIENKGDAFVNSLQLDVVGDSAVDDYEK--RRPSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGVERRRIYDIVNVLESLHLVSRVAKNQYGWHGRHSLPKTLRTLQRLGEEQKYEEQMACLQQKELDLMEYRFGERRKDGSPDPRDQHLLDFSESDYPSSSANSRKDKSLRIMSQKFVMLFLVSKTKIVTLDVAAKILIEESQDTPDHSKFKTKVRRLYDIANVLTSLALIKKVHVTEERGRKPAFKWIGPVDFSSIDEELLDVSASVLPELKKETYGQIRVCAKERLARYGSFNTVQTSEKIQRKVNSEPSSPQG-GKQGP-AYSLEIGSLAAIYRQKVEDSSQGEAFVNKRAAPPASVLD-----PTLPVDSEYCVKPLAQPVFSVAQTDLQAFSAQNGLNGQVGVPVPSAASDAETLKSALLASQPLVYVPSTSLFMLYGSVQEALSPESRSEEDGSGSDVPA--DLSLAPTAQKRLCEERNPLED-DEPAVKRQSREFEDSPLSLVMPKKPSNSTDLAFPVTTGNGRATPLEDACVKGQLPAAEDASGRAVPNGFIASECGNPSRNPDTEKSSNDNEITKDPSLLQYLYVQSPAGLNGFNMLLPGGQTPHAVAPSSAAMPSFGVPCMFLPSPGLGPFPVLYSPAIPGPISSAPGTLPNTGPMNFGLSTLASASHLLISPAAMVNPKSSTLPSADPQLRCQPPLNPNPVMPGSHGVIH-PESPGYMRHPVSMVKAEQSPAPATPKSIQRRHRETFFKTPGSLGDPAFRR-ERNQSRNTSSAQRRLEISSSGPD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6S7F2-1", "uniprot_id": "E2F7_MOUSE", "id": "Q6S7F2-1", "name": "Transcription factor E2F7", "aln": "-MEVNCLTLKDLISPRQTRLDFAIEDAE--NAQKENIFVDRSRMTPKTPMKNEPIDLSKQRIFTPDRNPITPVKPVDRQPQVEPWTPTANLKMLISAASPDIRDREKKKELFRPIENKEDAFVNSLQLDVAGDGAVDEYEK--QRPSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGVERRRIYDIVNVLESLHLVSRVAKNQYGWHGRHSLPKTLRTLQRLGEEQKYEEQMACLQQKELDLMGYRFGERRKDGSPDPRDPHLLDFSEADYPSSSANSRKDKSLRIMSQKFVMLFLVSKTKIVTLDVAAKILIEESQDTPDHSKFKTKVRRLYDIANVLTSLALIKKVHVTEERGRKPAFKWIGPVDFSSIDEELLDVSASILPELKKEAYGQIRVCAKERLVRYGSFNTVHTSEKIQRKVSSEPSSPQG-ERQGS-AYSLEIGSLAAIYRQKVEDNSQEEAFVSNTAVPPASILD-----PALSMDSEYCVKPLAQPVFSVAQTDLPAFSAQNGPSGQVGVPVPSAASDTENLKPALLAGQPLVYVPSTQLFMLYGSVQEGLSPESRSEEDGGGSDVPA--DLSVTPSAQKRLCEERDPQEEEDEPAMKRQSQEFEDSPLSLVMPKKPSSSTDLACPVTMGNGSSPPLEDACVKGQLPAAEEVTGKAAPNCYVASECGNPARNPDTEKPSNENEITKDPSLMQYLYVQSPAGLNGFNMVLPGTQTPHTVAPSPAQLPSFGVPCMFLQSPGLGPFPVLYSPAIPGPISSAPGTHPNPGPMNFGLSTLASASHLLISPAAMVNPKPSTLPCTDPQLRCQPSLNLNPVMPGSHGVIH-PESPCYVRHPVSMVKAEQSPAPATPKSIQRRHRETFFKTPGSLGDPVFRRKERNQSRNTSSAQRRLEISSSGPD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96AV8-1", "uniprot_id": "E2F7_HUMAN", "id": "Q96AV8-1", "name": "Transcription factor E2F7", "aln": "-MEVNCLTLKDLISPRQPRLDFAVEDGE--NAQKENIFVDRSRMAPKTPIKNEPIDLSKQKKFTPERNPITPVKFVDRQ-QAEPWTPTANLKMLISAASPDIRDREKKKGLFRPIENKDDAFTDSLQLDVVGDSAVDEFEK--QRPSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGVERRRIYDIVNVLESLHLVSRVAKNQYGWHGRHSLPKTLRNLQRLGEEQKYEEQMAYLQQKELDLIDYKFGERKKDGDPDSQEQQLLDFSEPDCPSSSANSRKDKSLRIMSQKFVMLFLVSKTKIVTLDVAAKILIEESQDAPDHSKFKTKVRRLYDIANVLTSLALIKKVHVTEERGRKPAFKWIGPVDFSSSDEELVDVSASVLPELKRETYGQIQVCAKQKLARHGSFNTVQASERIQRKVNSEPSSPYR-EEQGSGGYSLEIGSLAAVYRQKIEDNSQGKAFASKRVVPPSSSLDPVAPFPVLSVDPEYCVNPLAHPVFSVAQTDLQAFSMQNGLNGQVDVSLASAASAVESLKPALLAGQPLVYVPSASLFMLYGSLQEGPASGSGSERDDRSSEAPATVELSSAPSAQKRLCEERKPQEE-DEPATKRQSREYEDGPLSLVMPKKPSDSTDLASPKTMGNRASIPLKDIHVNGQLPAAEEISGKATANSLVSSEWGNPSRNTDVEKPSKENESTKEPSLLQYLCVQSPAGLNGFNVLLSGSQTPPTVGPSSGQLPSFSVPCMVLPSPPLGPFPVLYSPAMPGPVSSTLGALPNTGPVNFSLPGLGSIAQLLVGPTAVVNPKSSTLPSADPQLQSQPSLNLSPVMSRSHSVVQQPESPVYVGHPVSVVKLHQSPVPVTPKSIQRTHRETFFKTPGSLGDPVLKRRERNQSRNTSSAQRRLEIPSGGAD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RIX9-1", "uniprot_id": "E2F7_DANRE", "id": "Q5RIX9-1", "name": "Transcription factor E2F7", "aln": "MQEVKCLTLKDLLGVRTLVNKTGSDDAASMNDHKENICMDRRKMTPLKSESLTAALNGHGKISSPEITHITPIKLTEKA-HPDPWTPTANLKMLINAASPDIRDREMKKTLFKPIENKGKIAEEEEEEELDDSCQYEALDESERRPSRKQKSLGLLCQKFLALYPDYPESSESINISLDEVATCLGVERRRIYDIVNVLESLMLVSRKAKNMYVWHGRSRLPQTLQGLLQAGRDQHYDLLMD---------------QREGNG--------LHAVQHVQNAHAASSRRKDKSLRIMSQKFVMLFLVSKTQTVTLDMAAKILIEEGQEESYDSKYKTKVRRLYDIANVLTSLNLIKKIHMREEKTRKPVFKWIGPGNFQS---------SSNSDDLRGQIS-NSGTERREKMARHSSFQVITAPPVNQRLISSAPSTPHRYSTDEPVDYSRKSGNNSAVCRLQFGDG----------------------------------VHPSVSPAVPSALASL-AMPLQADL-----MPVPASFS------------HPLAILPQTPLLMLY----------SGNISDG-------------ASSLRKR---ERSEEDDHQTTKCRRRSASIESD----TVESESLSSSTRRSPVCSPEGS--PWDEASFGG--LHEDDVAASSSKDALLS---------------------------PHYLYVPNTAGLNSFNFLLP-------AGHAQGGVPAVAMPYFVVQSP-------LIAGAMP--------TSSTEGAAGFSVPTVLSPAQFVMAGGAYG--VTEILQSPE-HHGNVPATTSSPRAE---------ESP----------KPAQTQTPVTPKEASLGS-KSFFETPGAFGSLVNQS----AARKRGSAQRRLDIGHTAAN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:*******:. * . . :*. . :**** :** :*:* .. . . .: : :*: . ***:* .:: : :************.********** ** **:***** . :. : :: .. : :: :****************** **.** *:*. .*******..****************** **** *** * **** **:**: * : *.:*:*: * :*. :* * ... : . :::. **********************: ****:********.*: . .**:***************** ****:*: **: ***.****** :*.* :* :*: : : . ::::.*:.**:.: :. ** :.* **:* : . ** : *. :*: * :. *. *:* . *... * :.* *:. * . :.:.:: * :**. :*.: *:*** * . *. :.: :** **. :: : . :*:* . *.. .: .:. .*: * : * .: . * :: :. : : :: :** * ..****.**.:*. .. : . :*:..:* :.: ** * : *:* : .. *. .*.:. : * :::::. * .. * ..: : *. . .* *** * *: .*.***. . ::**:***::*. . : :*: .******:* ..:", "identical_positions": 292, "similar_positions": 232, "identity": "31.77%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3529", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5SWW4-1", "uniprot_id": "MED13_MOUSE", "id": "Q5SWW4-1", "name": "Mediator of RNA polymerase II transcription subunit 13", "aln": "-MSSSFVSNGASLEDCHCNLFCLADLTGIKWKRYVWQGPTSAPILFPVTEEDPILSSFSRCLKADVLGVWRRDQR---------------------------PGRRELWIFWWGKDPNFADLIHHDLSEEED------GVWENGLSYECRTLLFKAVHNLLERCLMNRNFVRIGKWFVKPYEKDEKPINKS-EHLSCSFTFFLHGDSNVCTSVEINQHQPVYLLSEEHVTLAQQSNSPFQ------------------------------------------------VILSPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPIS--------------CGLKEMSEEK-----QDDMDWEDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPAPSSVGASH-CSASCLGIHQVPASTRDPAMS--SVTLTPPTSPEEVQTVDPQSAQKWVKFSSVSDGFSTDSTS-----HHGGKIPRKLANHVVDRVWQECNMNRLQNKRKYSATSSG--------------------------------LCEEETADKIGCWDFVEATQRTSCSCLRHKSLKTRNTGQQGQAPSLGQQQQ-VLPKHKTNEKQDKSEKPQKRPLTPFHHRVSVSDEIG-MDTDSASQRLVISAADSQVRFSNIRTNDVA--KTPQMHG--TELANSPQPPPLSPHPCDVVDEGVT--KTPSTPQSQHFYQMPTPDPLVPTKP-MEDRIDSLSQS----------FPPPFQEAVEPTVYVGTAVSLEEDEANVAWKYYKVPKKKDVEFLPPQLPNDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDEIVQQYQIK-NQYLSAIASDTEQEPKIDPYAFVEGDEEFIFTDKKDRQNSEREAGKKHKVEDGTSAVTVLSHEEDAMSLFSPS------------------------KQDAPRPTNHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELT--------PGSKKSASG----------------SDDKASSKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMN---------------------------------------MNNKEYGSVDTAPGGTVLEGNSSSVGTQFRIEVEEGFCSPKPSEIKDFSYVYKPENCQVLVGCSMFAPLKTLPSHCLPPIKLPEECVYRQSWTVGK---LDLLPSGPSMPFIKEGD-----GSNLDQDYGPAYTPQTHASFGMPPSSAPPSNGGAG-------ILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENS--------------------------------------------------DLYSPASTPSTCR-------------------------------------------------PLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCNMN------IKGADVGVYIPDPTQEAQYR-------------------------------------------------------------------------------CTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEAEKRFEALRASSVENVNGGLKES-------------------EKVPDELILLLQDQCTNLFSPFGAADQDPFPKVGISSNWVRVEER------------------DCCSDCCLALEHGRQFMDN-------------MSGGKVDEALVRSSCLHPWAKQN------------------DASVQCSQDILRMLLSLQPVLQDAIQKKRTVRPWG--------VQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLGYDYDFLVLSPFALPYWEKLMLEPYGSQRDIAYVVLCPENEALLNGARSFFRDLTAIYESCRLGQHRPISRLLTDGIMKVGATASKKLSEKFVTEWFSQAADGNN--EAFSKLKLYAQVCRYDLGPYLASQPLDSSLLSQPNLVAPPNQSLVTAPQMTNTGNANAPSATLASAASSTMTMTSGVPISTSVATANSTLTTTSSSSSSS--LSSGVSSNKLPSFPPFGSMNTSGTGSMSAQASTVQSGQLGGQQSSSLQAAGISGESASLPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAIVVYIIDPFTYENKDESTNSSNVWTLGLLRCFLEMVQTLPPHIKSTVSVQIVPCQYLLQPVKHDDRQIYSQHLKSLAFSVFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPE--CIRLYTPPFILAPVKDKQ------TELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCIINIDVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLG-RIGHGELKDWSCLLSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRSTTLNMQTPQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMG-IFDLLDTGDDLDPDIINILPASPTA--SPVHSPGSHYPHGGDAGKGQGTDRLLSTESHDEVTNILQQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQ-------SDELLHSKHSHPLDSNQTSDVLRFVLEQYNALSWLTCDPAVQDRRSCLPVHFVVLNQLYNFIMNML", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LXU0-1", "uniprot_id": "F1LXU0_RAT", "id": "F1LXU0-1", "name": "Mediator of RNA polymerase II transcription subunit 13", "aln": "-MSSSFVSNGASLEDCHCNLFCLADLTGIKWKRYVWQGPTSAPILFPVTEEDPILSSFSRCLKADVLGVWRRDQR---------------------------PGRRELWIFWWGKDPNFADLIHHDLSEEED------GVWENGLSYECRTLLFKAVHNLLERCLMNRNFVRIGKWFVKPYEKDEKPINKS-EHLSCSFTFFLHGDSNVCTSVEINQHQPVYLLSEEHVTLAQQSNSPFQ------------------------------------------------VILSPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPIS--------------CGLKEMSEEK-----QEDMDWEDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPTPSSVGSSH-CSASCLGIHQVPASTRDPAMS--SVTLTPPTSPEEVQSVDPQSAQKWVKFSSVSDGFSTDSTS-----HHGGKIPRKLANHVVDRVWQECNMNRLQNKRKYSATSSG--------------------------------LCEEETADKIGSWDFVEATQRTSCSCLRHKSLKTRNTGQQGQAPSLGQQQQ-ILPKHKTNEKQEKSEKPQKRPLTPFHHRVSISDDIG-MDTDSASQRLVISAADSQVRFTNIRTNDVA--KTPQMHG--TELANSPQPPPLSPHPCDVVDEGVT--KTPSTPQSQHFYQMPTPDPLVPTKP-MEDRIDSLSQS----------FPPPFQEAVEPTVYVGTAVSLEEDEANVAWKYYKVPKKKDVEFLPPQLPNDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDEIVQQYQIK-NQYLSAIASDTEQEPKIDPYAFVEGDEEFIFTDKKDRQNSEREAGKKHKVEDGTSAVTVLSHEEDAMSLFSPS------------------------KQDAPRPANHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELT--------PGSKKSASG----------------SDDKASSKESKTGSLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMN---------------------------------------MNNKEYGSMDPTPGGTVLEGSSSSVGTQFRIEVEEGFCSPKPSEIKDFSYVYKPENCQVLVGCSMFAPLKTLPSHCLPPIKLPEECVYRQSWTVGK---LDLLPSGPSMPFIKEGD-----GSNLDQDYGPAYTPQIHTSFGMPPSSAPPSNGGAG-------ILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENS--------------------------------------------------DLYSPASTPSTCR-------------------------------------------------PLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCNMN------IKGADVGVYIPDPTQEAQYR-------------------------------------------------------------------------------CTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEAEKRFEALRASSVENVNGSLKES-------------------EKVPDELILLLQDQCTNLFSPFGAADHDPFPKAGISSNWVRVEER------------------DCCSDCCLALEHGRQFMDN-------------MSGGKVDEALVRSSCLHPWAKQN------------------DASVQCSQDILRMLLSLQPVLQDAIQKKRTVRPWG--------VQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLGYDYDFLVLSPFALPYWEKLMLEPYGSQRDIAYVVLCPENEALLNGARSFFRDLTAIYESCRLGQHRPISRLLTDGIMKVGATASKKLSEKFVTEWFSQAADGNN--EAFSKLKLYAQVCRYDLGPYLASQPLDSSLLSQPNLVAPPNQSLVTAPQMTNTGNANAPSATLASAASSTMTLTPGVAISTSVATANSTLTTTSSSSSSS--MSSGVSSNKLPSFPPFGSMNTSGTGSMSAQGSTVQSGQLGGQQSSSLQAAGISGESASLPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAIVVYIIDPFTYENKDESTSSSNVWTLGLLRCFLEMLQTLPPHIKSTVSVQIVPCQYLLQPVKHDDRQIYSQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPE--CIRLYTPPFILAPVKDKQ------TELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCIINIDVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLG-RIGHGELKDWSCLLSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRSTTLNMQTPQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMG-IFDLLDTGDDLDPDIINILPASPTT--SPVHSPGSHYPHGGDAGKGQGTDRLLSTESHDEVTNILQQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQ-------SDELLHSKHSHPLDSNQTSDVLRFVLEQYNALSWLTCDPAIQDRRSCLPIHFVVLNQLYNFIMNML", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UHV7-1", "uniprot_id": "MED13_HUMAN", "id": "Q9UHV7-1", "name": "Mediator of RNA polymerase II transcription subunit 13", "aln": "-MSASFVPNGASLEDCHCNLFCLADLTGIKWKKYVWQGPTSAPILFPVTEEDPILSSFSRCLKADVLGVWRRDQR---------------------------PGRRELWIFWWGEDPSFADLIHHDLSEEED------GVWENGLSYECRTLLFKAVHNLLERCLMNRNFVRIGKWFVKPYEKDEKPINKS-EHLSCSFTFFLHGDSNVCTSVEINQHQPVYLLSEEHITLAQQSNSPFQ------------------------------------------------VILCPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPIS--------------CCLKEMSEEK-----QEDMDWEDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPTPSPVGSTH-CSSSCLGVHQVPASTRDPAMS--SVTLTPPTSPEEVQTVDPQSVQKWVKFSSVSDGFNSDSTS-----HHGGKIPRKLANHVVDRVWQECNMNRAQNKRKYSASSGG--------------------------------LCEEATAAKVASWDFVEATQRTNCSCLRHKNLKSRNAGQQGQAPSLGQQQQ-ILPKHKTNEKQEKSEKPQKRPLTPFHHRVSVSDDVG-MDADSASQRLVISAPDSQVRFSNIRTNDVA--KTPQMHG--TEMANSPQPPPLSPHPCDVVDEGVT--KTPSTPQSQHFYQMPTPDPLVPSKP-MEDRIDSLSQS----------FPPQYQEAVEPTVYVGTAVNLEEDEANIAWKYYKFPKKKDVEFLPPQLPSDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDELVQQYQIK-NQCLSAIASDAEQEPKIDPYAFVEGDEEFLFPDKKDRQNSEREAGKKHKVEDGTSSVTVLSHEEDAMSLFSPSI-----------------------KQDAPRPTSHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELT--------PGSKKSANG----------------SDDKASCKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMN---------------------------------------MNNKEYGSMDTTPGGTVLEGNSSSIGAQFKIEVDEGFCSPKPSEIKDFSYVYKPENCQILVGCSMFAPLKTLPSQYLPPIKLPEECIYRQSWTVGK---LELLSSGPSMPFIKEGD-----GSNMDQEYGTAYTPQTHTSFGMPPSSAPPSNSGAG-------ILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENS--------------------------------------------------DLYSPASTPSTCR-------------------------------------------------PLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCNMN------IKGADVGVYIPDPTQEAQYR-------------------------------------------------------------------------------CTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEAEKRFEALRATSAEHVNGGLKES-------------------EKLSDDLILLLQDQCTNLFSPFGAADQDPFPKSGVISNWVRVEER------------------DCCNDCYLALEHGRQFMDN-------------MSGGKVDEALVKSSCLHPWSKRN------------------DVSMQCSQDILRMLLSLQPVLQDAIQKKRTVRPWG--------VQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLGYDYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESCRLGQHRPVSRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNN--EAFSKLKLYAQVCRYDLGPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMTNTGNANTPSATLASAASSTMTVTSGVAISTSVATANSTLTTASTSSSSSSNLNSGVSSNKLPSFPPFGSMNSNAAGSMSTQANTVQSGQLGGQQTSALQTAGISGESSSLPTQPHPDVSESTMDRDKVGIPTDGDSHAVTYPPAIVVYIIDPFTYENTDESTNSSSVWTLGLLRCFLEMVQTLPPHIKSTVSVQIIPCQYLLQPVKHEDREIYPQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALRSPDRPE--CIRLYAPPFILAPVKDKQ------TELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCIINIDVPNRARRKKSSARKFGLQKLWEWCLGLVQMSSLPWRVVIGRLG-RIGHGELKDWSCLLSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRSTTLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMG-IFDLLDTGDDLDPDIINILPASPTG--SPVHSPGSHYPHGGDAGKGQSTDRLLSTEPHEEVPNILQQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQ-------SDELLHSKHSHPLDSNQTSDVLRFVLEQYNALSWLTCDPATQDRRSCLPIHFVVLNQLYNFIMNML", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2VCZ5-1", "uniprot_id": "MD13L_DANRE", "id": "A2VCZ5-1", "name": "Mediator of RNA polymerase II transcription subunit 13-like", "aln": "-MSSCFVPNGASLEDCHSNLFCLADLTGIKWKCFVWQGPTSSPILFPVTEEDPILCSFSRCLKADVLSVWRRHQT---------------------------PGRRELWIFWWGDDPNFAELVHHDLSCNED------GSWESGLTYECRTLLFKAIHNLLERCLMNRSFVRIGKWFVKPYEKDEKPINKS-EHLSCSFTFFVHGDSNVCTSVEINQHQPVYLLSEEHLTLAQQSSSSVQ------------------------------------------------VILSPYGLSGTLTGQSFKLSDPPTQKLIEEWKQFYPIG--------------PNTKEVTDDK-----MDDLDWEDDSLAAVEVVVAGVRMVYPASLVLVAQSDIPLVATVSSSS-SSGSYAGAPHNQLVHGDTGIS--SVTLTPPTSPEEAQAVS-QPAQKWVKLSAMSGVFSVDSSS-----HHGGKIPRRLASQMVERVWQECNINRAQNKRKFSTMSNG--------------------------------VCEEET-DKASVWDFVESSQRSQCSCSRLKNQKQRACSTPGHPPSAGQPPQ-PSTKHKMAEKLEKGDKQQKRPLTPFHHRSSLCEEQPSLEQGESVHRLCLQGHE-DSRYPSLHHADVTSSKTPMLHSSADEMAGSPQPPPLSPHPCERMEEPADGMKSSSSPLHQHFYPPSSEPCLEPQKPPDESTLDPLPLP----------CPPPYPETLEATIYVGSAINPNEDTTHNPWKYFRVPGGRNSDFHTPHLPVVAHFEDGNRTGGQDGIVSITEMMSSSKRPLKVSEELVKMYEHKKNQYLSSAVCDEDPEQESDPYAFEEGDEEFNFSDKDKKSGPEREAGKKAKREDGSSSS-----------------------------------------DDAQGSGGSKPLPTTSLIHETDLVVSINDLDNLFNSDEDDLTQ-------PGSRRAAGG----------------AEEKFGGKEPKPAAPDPLPCC--ADLHQMFPTPPSLDQ---GYSPIN---------------------------------------MGN-----TESAAGLSLLDG---AMSGNFKMEVEEGFCSPKPSEIKDFSYVFKPESCQALIGCSLYAPLKTLPSQCLLPVKLPEECVYRPSWTVGK---LGMLQPMAAMTFLNKDSNIPSVGSVVEQEQ--SCTPQTHNTFMS--NSAPPSNSGAG-------ILPSPATPRISAP-TPRTPRTPRTPRGPASVQGSLKYENS--------------------------------------------------DLNSPASTPSTCR-------------------------------------------------PLSSVEPATVPSIPEAHSLYVTLILSESVMNLFKDCNFDSCCICVCNMN------ITGADVGIYISDPNMDSQYSSMDP---------------------------------------------------------------------------CSCGFSAVMNRRYGNGAGLFLEDELDIMGRGSDAAREIEKHFEAVRAASLK---RGTVLE-------------------EQVPDDLMLLLQDLCTNPFSPIIRPD----LLGTVIKSPIRLEER------------------DYYSDCYMALEHGRQFMDN-------------MSGGKVDETLVKSSSLHHWAKRNAF----------------DMSMLFSQDVLRMLLSLQPVLQDTIQKKRSVRSWG--------VQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTLLVGYEYDYVVLSPFALPYWEKLLLDPYSSQRDVGYMVVCPDNEALLNGAKTFFRDLTAVYESCRLGQHRPIAKSHADGIVTVSDAGSKALTDQTLIDWLPKTINSSSSSEALNKLKLYAHVCRHDLASCLASQSLDGSLLTQRNPASSSQTSSSSSPVTTAQN--VTPTTNSNSNTNTNTTPTS---------------TSTSSSSSSCPQGVGNMPSSKPNTIPPFG-----AQGLQSSQQS-------GGQSAGTLGDATSATSQPQVPSEP----AESTMEREKVGVPTDGDSHAVTYPPAIVIYIVNPFSYEENCQGS-SSSVWTIALLRCYLEMLQLLPPHIRNAVYVQIIPSQYLLQPVWSEERHIYAQHLKSLAFSVYTQCRRRLPTSTNVKTLTGFGPGLAIDTALQSKERPQ--CLHLYAPPFVLAPVKDKQ------TELGETFGEAAQKYNVLFVAYCLSHDQRWLLASCTDQYGELLETCVISIDVPNRARRKKGSARRQGLQKLWEWCLDLVQMTSLPWRIVIGRLG-RIGHGELRDWSILLSRRNLQSLGRRLKEMCRMCGISAADSPSILSTCLVAMEPQASFVIMPDSVSTGSVFGRSTTLNMQTSQLNTPQDTSCTHILVFPTSAGLQ-------------AFSDVTDGMGGMDGILDLFAENDLVDPDLINIIPNSPTT--SPVHSPGSHYHHGGDGSKGQGTDR---MESHDESPNILQQPMALGYFVSTAKAGPLPDWFWSSCPQAKNQCPLFLKASLHLNVSSVQ-------SDELLHSKHSHPLDSSHTSDVLRFVLEQYNALSWLTCDPATQDRRSCLPVHFVVLNQMYNFIMNML", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KTX8-1", "uniprot_id": "MED13_DROME", "id": "Q7KTX8-1", "name": "Mediator of RNA polymerase II transcription subunit 13", "aln": "MTHQNHQTNGASLEDCHTNFYALTDLCGIKWRKFVNG---ERPNASSDPLADPILRSYSRCIQADMLCVWRRVQSTKTDHADPNALTFEMTTSTKVHPPLSLAAAKELWIFWYGEEPDLSELVDAELLRVAANQALWNGTWKGALTYECRSLLFKALHNLMERFVLTKDIVRFGKWFVQPCTSSDRLFGRSSQHLSFSFTFFVHGDT-VCASIDLREHPAVRPLTKEHLTEAAAAFAAASSPPGSNGSAASAGGAVPNPGQDPNGASMDGLDGGEGAAKAAPPPHARKVMLAPFGIAGILTGNSYKASDPIAEKILEDWASFFPLCNKDNTDVPPVVEVVSGGHKMYHPTNYVLVTDLDDMEHMEFVEMQKMQSSVAGAAAESAVLASLSCPPGAASAPSSMGAAPSATAVPLGPASLNAPALAGAGVGATASSAAKEISRKAAPQAVSALERLAFQPYYDQRPTSGFTFNTNNTHIPASAAVEMPERTWQDCVMNTLHVDAAAAAAAVASSTPASGTGSLSADGDENEQNKPPQDSKQLVQQQIQQQQQRQKLWNFVDPMQKAPCICTKHLGNTPHGTPHGGASTYSRNSLGGDSSMPVASVESPATPAPSPHPNSAHSQPTSVPPAEQLLNMSPHAPTSVSNLQQPPTPIDHLLDKNTPAPTPTDQHDSKSITASPYVHQTPSVEPPSYTDHAAGGGPAGGQGLGTGPGSVPAQQPATPTAATSAGGAGSGGPSNAIGANAVGTISVKKLEMQQQTPSAAMAIKQEPGAQGRGVGGVTSTTEALNNFKRLYNPPKLTLKDPDSFYDEEWLKEVIYDFQYQEYWDYSTVKRPKMEKQRRPRYAKNLYEGQNHVKPVMPSPGSVYGSQLLSLDESASQAGGRGGGGQAAGSSGGGLVGIANSTASGSDVEADGSSFFQGLNIKTEPGLHSPSCKETSKSSGGNSSGGGSGSGGNLFTAEGLNPSLNDLEQLFETSSNDECSSVQIHTPPDSNNPSNGGCSAVTNTIEDLKRSTAVASAAVAAAAAAAASGAGNIQAEDLTKMFPTPPSHEQQHPNSSPCQTDVVMTDLSVDTTTTIITSSITTTCNTTITSSINTTTTACSNPSNSIMLAAAQAPVTVVAIQTVSKMVKQEYNLELGSPMEEPINDWDYVYRPPQQEKFVGSTRYAPLTNLPSQTQPPLTLPTGCFYQPTWSSHKSRAATLAKAAAAQQQQHQKHQALQQRIQLHQQKLQQLQLQNQQQQQAAAAAAAAASGGVGHQKHQHQHLHDLLSAAPRTPLTPSTVPQPLSSGGSQYLLNQLNCPQAPPGASMQQLMHRAGMSPISPGPGMGPYAARSSPMSRATPTHPPPPYPYDLAVASPATSTSSYLNRPLHSQEHPHMHGLGGGATGVVGHGTGGGGHMGMVAYTGDAGIVSGGTAMAAGSSSLLQELPEVNSVLVNILLYDTALNVFRDHNFDSSSVCVCNADTQKIGNIRGADSGVYVPLPGVSFNPFPSGAGGALAGQRMLNGPSSAGFGGMRMISAFGGSPASASMPGAGSGHGHGPNGGSNSSSCTPPSSNPHITGYVDDDPVECTCGFSAVVNRRLSHRAGLFYEDEVEITGIADDPGRNKQPTLLSIIQSLSRKNQNKQGPGETSSALDKIGAGGLPNGQLEQLGHAVFDLLLDQCSIIQTSSSSVHRALQSHRRRMSRQRRIFGNNGAPTASLASIANVLEFMDAHDVISLALEQSRLAFENQRMDNMMDFHGNGSSSSHQQQQLTAFHAPPPALRHKLAGIGAGRLTVHKWPYLPVGFTRSNKEIVRTMNAIQPMLQNAFHCKSRGGSGSKDASSYNTVSGPLTWRQFHRLAGRASG----QCEPQPIPSVVVGYEKDWISVAPHSIHYWDKFLLEPYSYARDVVYVVVCPDNEHVVNCTRSYFRELSSTYEMCKLGKHTPIR--GWDGFLQVGAARNNVPADRETTPLDDWLRTLEH-AALAEQIRRYAVAFIHQLAPYLSRVPNDKTLLNPPDGSGNSHSKGGSSCSSNSSSVSGLPGGDLP--------------------------TDNIKLEPGTEPQVQPMETNEIKQEPGVGK---------------------GGTAAGETKPTLILGDP-----------------------LGMGETLEDINPSAIVLYVVNPFTFAS--DSCELERLALIALLRCYAELLKAVPDSVRSQMNIQIISLESVMELGPCGNRKRFSDEIRCLALNIFSQCRRHLVHAQSVKSLTGFGTAANMEAFLKTKDEPNRRAYKMYTAPFVLAPMHERNDKTDFSRSAGSMHGQNEHRYSVMYCNYCLSEDQAWLLATATDERGEMLEKICINIDVPNRARRRKAPARYVALKKLMDFIMGIISQTSQMWRLVIGRIG-RIGHSELKSWSFLLSKQQLQKASKQFKDMCKQCTLMYP--PTILSACLVTLEPDAKLRVMPDQFTPDERFSQIS----MQNPLATPQDVTCTHILVFPTSAVCAPFTR----------QFQNEPQVDDDFLTFEEEGNEDFSDADIGDLFWDTHMDRVSNHGSPGRMDDNRSWQSAGGNNFKCTPPQEVEEVGSLNQQPISVGYMVSTAPTGRMPAWFWSACPHLEDVCPVFLKTALHLHVPSIQSADDILNSTNAHQSGNDHPLDSNLTADVLRFVLEGYNALSWLALDSNTHDRLSCLPINVQTLMDLYYLTAAIA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38931-1", "uniprot_id": "SSN2_YEAST", "id": "P38931-1", "name": "Mediator of RNA polymerase II transcription subunit 13", "aln": "---MSSDASTYRLEDVLSSFYRVEKIKKINYHQYISK----AQNDQWSIQMEFMLRKQDPKTLVALLS-------------------------------------RDLWCFSINDDPVPTPPAIEHKPVSPDK----IGTFTADYSKPNLPPHYALFLKALRRKIYINLALGSHNKLIQFGNACISLSGVPNYLVQLEPHLFVNGDLTVSLCAKN---MGLVPMKEENLEESFLSKHALY--------------------------------------------------LAPSGIRMHLAPASKQGYLITPPKHTELLLTTLSVS------------------------------HGINLQNKKNLKWVAVVPDLGHLN------------------------------------------------GHTPTIASYLTPLLEAKKLVWPLHLIFAQPVADIENST-----------SGDPSEFHCLQDALDAIDDFIQLKQTAAYRTPG----------------------------------------------------SSGVLSSNIAGTNPLSSDGAYTEQFQHYKNNSISSQPASYHSVQETNKISPKDFSPNFTGIDKLMLSP----------------------------------------------SDQFAPAFLNTPNNNINENELFNDRKQTTVSNDLENSPLKTELEANGRSLEKVNNSVSKTG------------------SVDTLHNKEGTLEQREQNENLPSDKSDSMVDKELFGEDEDEDLFGDSNKSNSTNESNKSISDEIT--EDMFEMSDEEENNNNKSINKNNKEMHTDLGKDIPFFPSS-----------------------------------------------------------------------------------------EKPNIRTMSGTTKRLNGKRKYLDIPIDEMT--------------------------------------------------------------LPTSP----------------------------------------------------------------------------------LYMDPGAPLPVETPRDRRKSVFAPLNFNPIIENNVDNKYKSGGKFSFSPLQKEEALNFDISMADLS------------------------SSEEEEDEEENGSSDEDLKSLNVRDDMKPSDNISTN---------------------TNIHEPQYINYSSIPSLQDSIIKQEN-------------------------------------------------FNSVNDANITSNKE-------------------------------------------------GFNSIWKIPQNDIPQTESPLKTVDSSIQPIESNIKMTLEDNNVTSNPSEFTPN----------------------------------------------------------------------------------------------------MVNSEISNLPKDKSGIPEFTPADPNLSFESSSSLPFLLRHMPLASIPDIFITPTPVVTISE---------------------KEQDILDLIAEQVVTDYN---------------------ILGN---------------------------LGIPKIAYRG---------------VKDCQEGLITTTMLQLFSTFDR------------------------------------------------------------LNGNDTISKFYNMK---------------QPYVFVKKHHELIKVKHDSQPFIKFLNFRPPNGIKNFKSLLLSS---SFKEDCLSFAPTLSQTYINQELGFCELLKLTNED---PPGLMYLKAFDKNKLLLLAAQIVSYCS----------NNKNSIKNVPPILIILPLDNATLTELVDKANIFQVIKN--------------------------------------------------------------------------------------------------------------------------------------------------------------------EVCAKMPNIELYLKVIPMDFIRNVLVTVDQYVNVAISIYNMLPP-----------------KSVKFTHIAHTLPEKVNFRTMQ----QQQMQQQQQQQQQQQ---------------------------NNSTGSSSIIYYDSYIHLAYSRSVDKEWVFAALSDSYG---QGSMTKTWYVGNSRGKFDDACN----QIWNIALNLASKKFGKICLILTRLNGILPDDELMNWRRLSGRN--------------------------IHLAVVCVDDNSKISFIDE-----------------------------------------------------------------------------DKLYPSFKPIYKDTRFGGRMDMTRLYDYEIRDIDQDIHGIVFQHPFPLAHSQHRCAIRSGALIKFKKCDGDT------VWDKFAVNLLNCPHSDSTQLLETILEEFR--------NLAALNVWYGLSDGEDGHIPWHILAVKKMMNTLVHTRVKIANTSAATVHTATSSSIILSDK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. *** .:: : .: *::: :: : :* . . . :* ::** * ..:* : . * : : . : . : :.* : . : : ::: . . :. . :*::** *. . . : :.:*:: : : . *.* *: *: : : . * .: . : :. . : ..: *.. :. :. . . :: . : : :. : : . : : . : . . . . . . . : :. . . . * . :. . . .. . . . : :: .. :: .: : : : : : : : . . * . .: . .. : :: :: **.* : * . . *: * . : :: . .. . *: : : : . .:: : .. . ... * . ..: : . *. .*. : : .:*:..* .: :: . .::. : : .. :* : : : . : ::.: . . : :: . :: *: : . : . * : . . :: * . :.* * :*:.: * ..: . : : : : : . : : * . ::. :::.. . : :: *: * .** : * . : .. :: . * . * : *. . . : : * :::: : : . : : * : : ::: : * ..::: :: : :. : . . .. . :. *. * *: *::*: :* * : . ..:* : * :: : :.: . . ::: *:. : ..** .* * .:. : .:* :: :..: .: : * ..: : : . . : .: :. : : . . : .*. . ** .: * : . : : *... ..: .:* : :. *. . *. .:: . .: ", "identical_positions": 81, "similar_positions": 409, "identity": "2.98%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3548", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LUV8-1", "uniprot_id": "A0ABK0LUV8_RAT", "id": "A0ABK0LUV8-1", "name": "", "aln": "MGVAKSWGGTCSAEPGKRRKMAAVVAMDTQLMLGVGLIEKDTNGEVLWVWCYPSTTASLRNLLLRKCCLTDENKLLHPFVFGQYRRTWFYVTTVEVPDSSVLKKVTHFSIVLTAKDFNPEKYAAFTRILCRIYLKYGSPVKMMESYIAVLTKGICQSEENGSFLSRDFDGRKAYLAGSIKDIVSQFGMETIILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWSILHSYMHLHAEELEGLQMCTGYIAGFVDLEVSNRPDLYDVFVNLADSEIIIAPLAKEAMTMGKLHKEIGQLIVQSAEDPEKSDSQVIQDIALKTKEIFTHLAPFSEASDAG-KVFLNVEALKQKRFPPATENFLYHLAAAEQMLKADSYFIHGSLSSPLGAALLSVRLRAPGTVGTEASLLHKCCWEP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D8N2-1", "uniprot_id": "DEN10_MOUSE", "id": "Q9D8N2-1", "name": "DENN domain-containing protein 10", "aln": "--------------------MAAVVAMDTQLMLGVGLIEKDSNGEALWVWCYPSTTASLRNLLLRKCCLTDENKLLHPFVFGQYRRTWFYVTTVEVPDSSVLKKVTHFSIVLTAKDFNPEKYAAFTRILCRIYLKYGSPVKMMESYIAVLTKGICQSEENGSFLSRDFDGRKAYLAGSIKDIVSQFGMETVILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWTILHSYMHLHAEELEGLQMCTGYIAGFVELEVSNRPDLYDVFVNLADSEITIAPLAKEAMTMGKLHKEIGQLIVQSAEDPEKSDSQVIQDIALKTKEIFTHLAPFSEVSDDGGKVILNVEALKQQRFPPATENFLYHLAAAEQMLKV------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TCE6-1", "uniprot_id": "DEN10_HUMAN", "id": "Q8TCE6-1", "name": "DENN domain-containing protein 10", "aln": "--------------------MAAAEVADTQLMLGVGLIEKDTNGEVLWVWCYPSTTATLRNLLLRKCCLTDENKLLHPFVFGQYRRTWFYITTIEVPDSSILKKVTHFSIVLTAKDFNPEKYAAFTRILCRMYLKHGSPVKMMESYIAVLTKGICQSEENGSFLSKDFDARKAYLAGSIKDIVSQFGMETVILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWTILHSYVHLNADELEALQMCTGYVAGFVDLEVSNRPDLYDVFVNLAESEITIAPLAKEAMAMGKLHKEMGQLIVQSAEDPEKSESHVIQDIALKTREIFTNLAPFSEVSADGEKRVLNLEALKQKRFPPATENFLYHLAAAEQMLKI------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NSW5-1", "uniprot_id": "DE10B_HUMAN", "id": "Q6NSW5-1", "name": "Putative DENN domain-containing protein 10 B", "aln": "--------------------MAAAELADTQLMLGVGLIEKDTNGEVLWVWCYPSTTATLRNLLLRKCCLTDENKLLHPFVFGQYRRTWFYITIIEVPDSSILKKVTHFSIVLTAKDFNPEKYAAFTRILCRMYLKHGSPVKMMESYIAVLTKGICQSEENGSFLSKDFDARKAYPAGSIKDIVSQFGMETVILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWTILHSYVHLNADELEALQMCTGYVAGFVDLEVSNRPDLYDVFVNLAESEITIAPLAKEAMAMGKLHKEMGQLIVQSAEDPEKSESQVIQDIALKTREIFTNLAPFSEVSADGEKRVLNLEALKQKRFPPATENFLYHLAAAEQMLKI------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8E7G4-1", "uniprot_id": "DEN10_DANRE", "id": "A8E7G4-1", "name": "DENN domain-containing protein 10", "aln": "-------------------------MATPELMLSLGLIEKDVNADTLWVWCYPSIDADLREVMLRKCCLTLDNQVLHTFVFGQFCRTWYYITTVEVQEPTVLKKVTHFSIVVTAKDFNPEKYAAFSRVLCRTYMKHGSPVKMMEGYIAVLTKGICQSDENGSFLIKDYDVRKALLAGSLKDVVSQFGMETIILYTALMLKKRVVVYHPRIEALLEFTRALPCLVWHRKDWSILHPFVHLENDELENLKVCTGYVAGFVDPEVKDRSDLFDVFVNLPDSEITVSQNAKEAMSMGKLHKEIGNFIVQAAEDADRSDAQVIKDISVKTKEILSNLMSLADHADNS---KLTLECLKQGHYPPATENFLFHLAAAEQLLKI------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:***.:****** *.:.******** * **:::******* :*::**.*****: ***:*:* :** :.::**********:*************:*:*** *:*:********.************:****** :*:* *** ***:**:********:**:********:*****:***: ****:**.*****:**:***.::**. :*** *::****:****: **.:*.**:******.:*** :: *****:*******:*::***:***.::*:::**:**::**:**:::* .::: : . *.:*.*** ::********:*******:** ", "identical_positions": 229, "similar_positions": 90, "identity": "54.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-355", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CSU0-1", "uniprot_id": "RPR1B_MOUSE", "id": "Q9CSU0-1", "name": "Regulation of nuclear pre-mRNA domain-containing protein 1B", "aln": "MSSFSESALEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVSVWHRELRK--AKSNRKLTFLYLANDVIQNSK-RKGPEFTREFESVLVDAFSHVAREAD-EGCKKPLERLLNIWQERSVYGGEFIQQLKLSME----------------DSKSP-----------PPKAA-------EEKKS-LKRTFQQIQ---------EEE---DDDYPGSYSPQDP---SAGPLLTEELIKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKIT-----DKEAAERLSKTVDEACLLLAEYNGRLAAELEDRRQLARMLVEYTQN------------QKEVLSEKEKKLEEYKQKLARVTQVRKELKSHIQSLPDLSLLPNVTGGLAPLPSAGDLFSTD---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQG5-1", "uniprot_id": "RPR1B_HUMAN", "id": "Q9NQG5-1", "name": "Regulation of nuclear pre-mRNA domain-containing protein 1B", "aln": "MSSFSESALEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVSVWHRELRK--AKSNRKLTFLYLANDVIQNSK-RKGPEFTREFESVLVDAFSHVAREAD-EGCKKPLERLLNIWQERSVYGGEFIQQLKLSME----------------DSKSP-----------PPKAT-------EEKKS-LKRTFQQIQ---------EEE---DDDYPGSYSPQDP---SAGPLLTEELIKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKIT-----DKEAAERLSKTVDEACLLLAEYNGRLAAELEDRRQLARMLVEYTQN------------QKDVLSEKEKKLEEYKQKLARVTQVRKELKSHIQSLPDLSLLPNVTGGLAPLPSAGDLFSTD---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B9C1-1", "uniprot_id": "A0A8M2B9C1_DANRE", "id": "A0A8M2B9C1-1", "name": "", "aln": "MSSFSESALEKKLSELSNSQQSVQTLSLWIIHHRKHAALIVRVWHRELKK--AKSSRKLTFLYLANDVIQNSK-KKGPEFAKDFEGVLIDACSHVARDGD-DGCKKQMDRLLTIWQERNLYRPDFIQQLKLTID----------------DSESP-----------KHKTAG--QRNADDRKN-LKRSYQKVQ---------EEEEEEDDDYRGHYSPRETD--AAAPQLTEDLVKALQDLENAASGDAAVRQKIASLPQEVQDVSLLEKITA----DKQAADKLSKTVDEACLLLAEYNGRLAAELEDRRQLARMLTEYIQS------------QKDALNEREKKLEEYKQKLARVTQVRKELKSHIQSLPDLSLLPNVTGGLAPLPSAGDLFSTD---------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W039-1", "uniprot_id": "Q9W039_DROME", "id": "Q9W039-1", "name": "CID domain-containing protein", "aln": "MSAFTDSALLKKLAELNSSQQSIQTLSLWLIHHRKHSAAIVRTWQRELEN--VPEPKKLTFMYLANDVIQNSK-KKGPEYGKEYSLVLGKVFAHIGEKCNSDKLLGSLGRILNIWLERGVYDPKTIADWRSRLHKEAPGSSSSSNGKTNGDSEKPEKEKDHGGSGKPEKSERREKRKHEDRHSKSKRSRHHVQGSSANSAPPTEEVVSVEPENGHTPPYLP---LGEPPEPEELIRALTSIENSASSDAVVRERIAKLPQEISEISCISKLE-----DKDKAKELAIQVNEAVDLLNDYNARLAAEMEERSKLATMLRDFQAE------------QKELLSQAEQRLDEHKKKLAKMLGLQKEIHDHLSNLPDLTRLPDVTGGLAPLPSAGDLFNALH--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05543-1", "uniprot_id": "RT103_YEAST", "id": "Q05543-1", "name": "Regulator of Ty1 transposition protein 103", "aln": "-MPFSSEQFTTKLNTLEDSQESISSASKWLLLQYRDAPKVAEMWKEYMLRPSVNTRRKLLGLYLMNHVVQQAKGQKIIQFQDSFGKVAAEVLGRINQEFP-RDLKKKLSRVVNILKERNIFSKQVVNDIERSLK----------------TESSPVEALVLPQKLKDFAKDYEKLVKMHHNVCAMKMRFDKSS---------DELDPSSSVYEENFKTISKIGNMAKDIINESILKRESGIHKLQSTLDDEKRHLDEEQNMLSEIEFVLSAKDPSRLNKNVDEDNIIPTYEVGDGDDDDDDGDNDDDDDDDDDDKNYDDRSNDSNYGVTNISTTDKKNEVVEKTDSEHKNSTHNPSDNQFGMKRTHDMIGHDDANDIPEKKVHLDSKTSEDGTFNSEDGHYELDIEGHVGAQTDEGVENSGGVSSSIQDLLSKLAN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*:.. : .** *..**:*:.: * *:: : :.: :. *:. : . . :** :** *.*:*::* :* :: .: * .. .:: .. : *::.* **.:: . : : . :. ...* ... * .: . * . . . *.::: .:.: * :.:: . : :.::. : . :*: . . *. : : : :: . : . :*: : : . .: . : . . : .: . * . :*: . * . .* .. *.: ", "identical_positions": 37, "similar_positions": 127, "identity": "8.49%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3553", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q642F4-1", "uniprot_id": "SC22A_RAT", "id": "Q642F4-1", "name": "Vesicle-trafficking protein SEC22a", "aln": "MSMILSASVVRVRDGLPLSASTDCEQSAGVQECRKYFKMLSRKLAQFPDRCTLKTGRHNINFISSLGVSYMMLCTENYPNVLAFSFLDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQRTKQRYNNPRSLSTKINLSDMQMEIKLRPPYQIPMCELGSANGVTSAFSVDCKGAGKISSAHQRLEPATLSGIVAFILSLLCGALNLIRGFHAIESLLQSDGEDFSYMIAFFLGTAACLYQCYLLVYYTSWRNVKSFLTFGLICLCNMYLYELRNLWQLFFHVTVGAFVTLQIWLRQAQGKAPDHDV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH47-1", "uniprot_id": "SC22A_MOUSE", "id": "Q8BH47-1", "name": "Vesicle-trafficking protein SEC22a", "aln": "MSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQFPDRCTLKTGRYNINFISSLGVSYMMLCSENYPNVLAFSFLDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQRTKQRYNNPRSLSTKINLSDMQMEIKLRPPYQIPMCELGSANGVTSAFSVDCKGAGKISSAHQRLEPATLSGIVAFILSLLCGALNLIRGFHAIESLLQSDGEDLNYIIAFFLGTAACLYQCYLLVYYTSWRNVKSFLTFGLICLCNMYLYELRNLWQLFFHVTVGAFVTLQIWLRQAQGKAPDHDV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96IW7-1", "uniprot_id": "SC22A_HUMAN", "id": "Q96IW7-1", "name": "Vesicle-trafficking protein SEC22a", "aln": "MSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQLPDRCTLKTGHYNINFISSLGVSYMMLCTENYPNVLAFSFLDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQRTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFSVDCKGAGKISSAHQRLEPATLSGIVGFILSLLCGALNLIRGFHAIESLLQSDGDDFNYIIAFFLGTAACLYQCYLLVYYTGWRNVKSFLTFGLICLCNMYLYELRNLWQLFFHVTVGAFVTLQIWLRQAQGKAPDYDV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6E5-1", "uniprot_id": "A0ACD6B6E5_DANRE", "id": "A0ACD6B6E5-1", "name": "", "aln": "MSMVLFASVVRVRDGLPLSASTDYELDKGIQETKKHLKVLSKKLSQFPDRCSLRSGLYNINFTSSLGVGYLMVCTENYPNVLAFSFLDELQREFIVTYDTKRINSALRPFSFIEFDNFIRKTKLRYNSPRSLSTKINLADMQTEIKLRPPYQLSAEDIGSINGFSQHKESKYKG----IAPNQMLEAVTLSGIVACVLSILCGALNLLRGVHAIESVLQNDDEDFNYVIAFFLGTAACLYQCYLFAYFSFWRNIKSFLAFALICLCNMYLYELRNLWQILFHVTVGAFITLQIHLRRPQGKAPDYNV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:* ***:************* * . *:** :*::*:**:**:*:****:*::* :**** *****.*:*:*:****************:***.**: : *:*:**:.********::** ***.**********:*** *********:. ::** **.:. . . ** :.:* **..******. :**:*******:**.*****:**.*.:*:.*:****************:.*:: ***:****:*.*****************::********:**** **:.******::*", "identical_positions": 208, "similar_positions": 71, "identity": "67.75%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3554", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XI94-1", "uniprot_id": "FIRRM_RAT", "id": "Q5XI94-1", "name": "FIGNL1-interacting regulator of recombination and mitosis", "aln": "MSQNGAVATNGVMLEELSSWPEEICRRELPSVLPRLLSMYQCSESWIEHIRILKIIVEMFLPHMNHLTLEETLFSQILPKTIQLFDGMICELTSEARELSSQNLEIQITIRNILQTMVQIIGSLTGCVHHVCATQESIILGNIHSLPSFILHIIKSTFVHCKNSESVYSGRLHLVSDLLQTLFKEAYSLQKQLMELLDMVCLGPSEDENS-ILTMVEVIHSLMDICSVISSMDKAFHANTWKFIIKQSLKHQSVIRSQLKHKEIISSLCEDILFSFHSCLQLAEQTTEP---AAQDNADYRLFQKTLKLCRFFANSLLHYTKEFLPFLPDSCRTLHQLYLQIYSKFPPCLYTAKISKVQQEEIAGTFLVVLDPLLSQLLKSQSFVQTVLASKLDLPHELQLPQVLLLVVVVDKLPSQPEDVQTLWCT-----EDMTRMSILKAIFYNFGQFSGELSLPAHLQGVKGKGQAEVPVTLYQRICVHLCTFVASLHPTLFPELDAALLNAVLSTNMSTSLLAMDVWCFLARYGTAELGAHHVTLVAHLIKSCPGRCVQLTNLSVLLRRLFFFMAPAHQVEFIQKFSPREADNLHLWQYISFQALPADLRKQVTCEVTGVCTAQCRKWLSGSHTLAELDSLNTALSVLLTVCNSAGEALDSRQLTAVTEVVGQLWAFINVEQIISQPHVQQAFSLLLQLLAFFIQTVDLQLISQVVNVLTLVIKLEPPDHVSLAVLDFLSSLGKLYISQTLRDKVLPSLSCIVASLMVNRNWLLEQHTLEAFTQFAEGTKHEEIVSQCLGSEEIKNKVVSFLEKTESVGETEAATADNSGEQKTDTFWEPVAKVTLEEAKGSA----FQPCTKRARQELLLEEEYRSAFQTATRALETTEALLK--HSRAP-AWLLSELGALQERIEKLKCCVLRG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TQQ9-1", "uniprot_id": "FIRRM_MOUSE", "id": "Q3TQQ9-1", "name": "FIGNL1-interacting regulator of recombination and mitosis", "aln": "MSQDDAEVASGVVLEELSSWSEEMCRRELPSVLPRLLSMYQCSESWIEHIRILKIIVEMFLPHMNHLTLEETLFSQVLPKSIKLFDGMICELTSEARELSSQNLEIQVTIRNILQAMVQVIGGFTGCVRHVCATQKSVFLGSIQSLPSFILHIIKSAFVHCKNSECVYSGRLHLVSDLLQVLFKEAYSLQKQLMGLLDTVCLDPSVDENN-ALIMVGVIHSLLDICSVISGMDQAFHANTWKFIIKQSLKHHSVIKSQLRHKEIISSLCEDILFSFHSCLQLAEQITQP---AAQGNADYRLFQKTLKLCRFFANSLLHYTKECLPFLSDSCCTLHQLYLQIHSKFLS-LCAAKTSKAQQEEIASTFLVLLDPLISQLLKSQPFVQAVLASKLALPCELQLPQVLLLVVAMDKLPSQPQDVQTLWST-----EDMTRMSILKGIFYNFGQCSGELSLPTHLQGTKGKGQAEVPVTLYQHVCVHLCAFVASFHSSLFPRLDAALLNAVLSTNMSTSLLAMDVWCFLARYGTAKLGAHHVTLVAHLVKSCPGKCVQLTNLSILLKRLLFFMAAPHQVQFIQKFSPKEADNLHLWQYISLQAFDADLRKPVACELVRVCRAQCRKWLSSTRTLAELDSLNTALSVVLTVCNSAGEALDSRQLTAVTEVLGELWTFINVEQIISQPYVQQAFSLLLQLLAFFIQTVDLQLISQVVNVLTSVIKLEPPDHVSLAVLDFISSLGKLYISQTIRDKVLPSLSCILTSLIVNKNWLLEQHTLEAFTQFAEGTKHEEIVPQCLGSEEIKNKVVSFLEKTESVDEAEVATVDN-VKQEKGTFWEPAAKVTVEEVKTSA----FQPHTKRARRVLPFEEEYRSVFKAAARALETTEFLLK--HSLAP-AWLLPELEALQGRIEKLKRCVLTG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NSG2-1", "uniprot_id": "FIRRM_HUMAN", "id": "Q9NSG2-1", "name": "FIGNL1-interacting regulator of recombination and mitosis", "aln": "----------------------------------------------------------MFLPHMNHLTLEQTFFSQVLPKTVKLFDDMMYELTSQARGLSSQNLEIQTTLRNILQTMVQLLGALTGCVQHICATQESIILENIQSLPSSVLHIIKSTFVHCKNSESVYSGCLHLVSDLLQALFKEAYSLQKQLMELLDMVCMDPLVDDNDDILNMVIVIHSLLDICSVISSMDHAFHANTWKFIIKQSLKHQSIIKSQLKHKDIITSLCEDILFSFHSCLQLAEQMTQS---DAQDNADYRLFQKTLKLCRFFANSLLHYAKEFLPFLSDSCCTLHQLYLQIHSKFPPSLYATRISKAHQEEIAGAFLVTLDPLISQLLTFQPFMQVVLDSKLDLPCELQFPQCLLLVVVMDKLPSQPKEVQTLWCTDSQVSETTTRISLLKAVFYSFEQCSGELSLPVHLQGLKSKGKAEVAVTLYQHVCVHLCTFITSFHPSLFAELDAALLNAVLSANMITSLLAMDAWCFLARYGTAELCAHHVTIVAHLIKSCPGECYQLINLSILLKRLFFFMAPPHQLEFIQKFSPKEAENLPLWQHISFQALPPELREQTVHEVTTVGTAECRKWLSRSRTLGELESLNTVLSALLAVCNSAGEALDTGKQTAIIEVVSQLWAFLNIKQVADQPYVQQTFSLLLPLLGFFIQTLDPKLILQAVTLQTSLLKLELPDYVRLAMLDFVSSLGKLFIPEAIQDRILPNLSCMFALLLADRSWLLEQHTLEAFTQFAEGTNHEEIVPQCLSSEETKNKVVSFLEKTGFVDETEAAKVER-VKQEKGIFWEPFANVTVEEAKRSS----LQPYAKRARQEFPWEEEYRSALHTIAGALEATESLLQ--KGPAP-AWLSMEMEALQERMDKLKRYIHTLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5TYP4-1", "uniprot_id": "FIRRM_DANRE", "id": "Q5TYP4-1", "name": "FIGNL1-interacting regulator of recombination and mitosis", "aln": "-------MSQVTLLDEVSQWNQETCQQELKTVLPKLVAMHHDTDSWEEHTNILQIITSRFLPHLSLSDLETGCFSTALPKVVKVFASLLEEISKQIGGLSSQNTELQLFLRKILKTMVQTLECLSGCVRHVCSIEESVSFSNIRSLPSCILGVLKDTFQHCKDSEVMYSGRLSLVGDLLQGLFKEAYSLQKGLMELLDKINFEDTASEEE-ISDIVTVIHSLLDICLIISRLDIALHANTWKFIIKQSIKYQSLVEDRLHHTDISFALCEDLCRSVENCLELAQQIQQAGLQEAVHSPEYKLFQKATKMCRFFANTLVHYTKEFKVFLSKSCSRFHQLYLQINSKFLPSLCAPSVPPTLSEELRVAVLVPMDAMLTQMMSFQPFAESVLNPDHQSSAKLFLPQCLLLVNVMGKLSSQPEEALRLWSDGSQFPEETPRWSVFEAVFQSFRLCVLERLVPVCLPGVMLRGQAQGTVSLHQHVCVHMCACVAVLPAQHFPPLERSLLAAVLQADTQTALLATDVWCFLARYGTAELCYHHVVLIAHLLRACPAGGYQLFHLALVLRRLLFLMTPKHQVEFVERFPLSQEENLCVWRHTLLKCLCVEARVRVEEQVLDRATVVLEEWQNSGCRLGEIPRLNRILDCVLLVVGGSGTQNEC--VESLVKIISQLWSHMRSSQVQVHVTLQCTVKLLLSLSAVLIKSLEPHIILQAVSCLSGLSIHQCPDDLLLAALEFLASLGQIFIPPNIQGQVLPQISSLFNGFLTRPSWLILHHVLEAFGCFAEITNHEEVISQTLKTEEVKSKVLNFLSKTVSRQESEETRLER-LKEWKCVIEKHCQQMESEKSQPAQTPLTEEPCAKRARQETKAEEEYERYLQTAEGALKALQAIERSEHSPSPPQWVRARLQLLQTLITQINTTTEEQS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****:. ** ** *** :::* .:: *::.: ***** *:* :*:**::*** : ::***:*:*: ::*: : .*:**** :* ::*.:* ***:** :*** * **.**** ********** ** *** : : .::. :* *****:*** :** :* *:************:*::*::..:*:*.:* :****: *...**:**:* :. * ..:*:****: *:******:*:**:** **..** :******* *** . * :. . . .**: :.** :*.:::*::. *.* : ** .. . :* :** **** .:.**.***::. **. * .* *:::.:* .* * :*. * * :*:*: .*:*:*::***:*: :: : . *. *: :** ***.:: *:*** *.**********:* ***.::***:::**. ** :*:::*:**:*:*:. **::*:::*. : :** :*:: ::.: : * . :: . .:* . *.*: ** *. :* * ..:* : :: :::.:**:.:. .*: : :* :..*** * ..:*:::: ::* *.*. : : : ** : ** *:*::***:::*. ::.::**.:*.:. ::. .**: :*.**** *** *:***::.* * :** *.**:.**.** *:* : :. :: . : : :: *: : : :* :****: ****. ::: **:: : : : :. :* *: .: ** : ::: ", "identical_positions": 309, "similar_positions": 293, "identity": "33.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3562", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C166-1", "uniprot_id": "CPNE1_MOUSE", "id": "Q8C166-1", "name": "Copine-1", "aln": "-----------MAHCVTLVQLSVSCEHLIDKDIGSKSDPLCVLLQDVGG-AWAELCRTERVRNCSSPEFSKTLQIEYHFETVQKLRFGIYDIDNKTPELGDDDFLGGAECSLGQIVSSQTLTLPLMLKPGKPAGRGTITVSAQELKDSRVVTMEVEARNLDKKDFLGK-------------------------------------------------------------------------------SDPFLEFFRQG-DGKWQLAYRTEVVK-------NNLNPTWKRFSVSLQHFCGGDLSTPIQVR---CSDYDSDGSHDLIGTFHTTLAQLQ----AVPAEFECVHPEKQQRKKNYRNSGTVRVKTCRVETEYSFLDYVMGGCQINFTVGVDFTGSNGDP-------SSPDSLHYLSPTGVNEYLTALWSVGSVVQDYD-------------SDKLFPAFGFGAQVP----PDWQVSHEFALNFNPSNPYCAG---------IQGIVDAYRQALPQVRLYGPTNFAPIIN-----HVARFAAQAAQQRSASQYFVLLLLTDGAVTDVEATCKAVVDASKLPMSVIIVGVGGADFEVMEQLDADGGPLRTRSGEAAARDIVQFVPYRRFQNAPRETLAQTVLAEVPTQMVSYFRAQGWAPLKAPPTPGKGPAQAPQA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A1R8-1", "uniprot_id": "CPNE1_RAT", "id": "D4A1R8-1", "name": "Copine-1", "aln": "-----------MAHCVTLVQLSVSCDHLIDKDIGSKSDPLCVLLQDVGG-AWAELCRTERVRNCSSPAFSKTLQIEYYFETVQKLRFGIYDIDNKTPELGDDDFLGGAECSLGQIVSSQTLTLPLMLKPGKPAGRGTITVSAQELKDSRVVTMEVEARNLDKKDFLGK-------------------------------------------------------------------------------SDPFLEFFRQG-DGKWHLAYRTEVVK-------NNLNPTWKRFSVSLQHFCGGDLNTPIQVR---CSDYDSDGSHDLIGTFHTTLAQLQ----AVPAEFECIHPEKQQRKKSYKNSGTVCVKTCRVETEYSFLDYVMGGCQINFTVGVDFTGSNGDP-------SSPDSLHYLSPTGVNEYLTALWSVGSVVQDYD-------------SDKLFPAFGFGAQVP----PDWQVSHEFALNFNPSNPYCAG---------IQGIVDAYRQALPQVRLYGPTNFAPIIN-----HVARFAAQAAQQRTASQYFVLLLLTDGAVTDVEATCKAVVEASKLPMSVIIVGVGGADFEVMEQLDADGGPLRTRSGEAAARDIVQFVPYRRFQNAPRETLAMTVLAEVPTQMVSYFKAQGWAPLKTLPAPAKGPAQAPQV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99829-1", "uniprot_id": "CPNE1_HUMAN", "id": "Q99829-1", "name": "Copine-1", "aln": "-----------MAHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKTLQLEYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSSQVLTLPLMLKPGKPAGRGTITVSAQELKDNRVVTMEVEARNLDKKDFLGK-------------------------------------------------------------------------------SDPFLEFFRQG-DGKWHLVYRSEVIK-------NNLNPTWKRFSVPVQHFCGGNPSTPIQVQ---CSDYDSDGSHDLIGTFHTSLAQLQ----AVPAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVMGGCQINFTVGVDFTGSNGDP-------SSPDSLHYLSPTGVNEYLMALWSVGSVVQDYD-------------SDKLFPAFGFGAQVP----PDWQVSHEFALNFNPSNPYCAG---------IQGIVDAYRQALPQVRLYGPTNFAPIIN-----HVARFAAQAAHQGTASQYFMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAMEQLDADGGPLHTRSGQAAARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQGWAPLKPLPPSAKDPAQAPQA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BH47-1", "uniprot_id": "A0A8M2BH47_DANRE", "id": "A0A8M2BH47-1", "name": "Copine-3", "aln": "-----MYFNLMAAQCVSKVELSISCNNLLDKDVGSKSDPLCVLLQSVGDDKWTEVARTERVKNCQDPQFSTKLHIDYYFEKVQKLKFGVYDIDNKSVDLGDDDFLGGFEGTLGQIVSSRKLTRPLQLKAAKPAGKGTITITAEEVKDNRAIVMEIEAKNLDKKDLFGK-------------------------------------------------------------------------------SDPFLEFFKQDEDGKWQLVHRTEVIK-------NNLNPSWKKFTVSLHTFCNGDLNKPIKVE---CFDYDSDGSHDLIGVFQTNVSDLQKAVHGSPVEFDCIHPEKQKKKKSYKNSGVIKIKDCKLETQYSFLDYVMGGCQINFTVGIDFTGSNGDP-------RSPDSLHYLNPNGVNQYLSAIWSVGQVVQDYD-------------SDKLFPAFGFGAQVP----PNFQVSHEFPLNFNPNSPYCQG---------VEGIVNAYRSVLPQLRLYGPTNFSPIIN-----HVARIASGAAQQPNAAQYFVLLIITDGEITDLDQTRQSIVNSSKLPMSIIIVGVGEADFKAMEFLDGDNGVLKSITGESAVRDIVQFVPFKQFANAPKEALAQSVLAEVPSQLVTYFKMRNLPPVN-PPAPTK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6XLI7-1", "uniprot_id": "Q6XLI7_RAT", "id": "Q6XLI7-1", "name": "RNA-binding protein 12", "aln": "MAVVIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIVGGELGEAFIVFATDEDARLGMMRTGGTIKGSKVTLLLSSKTEMQNMIELSRRRFETANLDIPPANASRSGPPPSSGMSSRVNLPATVPSFNNPSPSVVTATTSVHESNKSIQTFSTASVGTAPPSMGTSFGSPTFSSTIPSTASPMNTVPPPPIPPIPSMPSLPPLPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTTLPPISGMPPLNPPPVAPLPTGMNGSGAPISLNNNLNPVFLGPLNPVNPIQMNSQSSVKSLPINPDDLYVSVHGMPFSAMENDVREFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQDTFEALKRNRMLMIQRYVEVSPATERQWVAAGGHITFKQSMGPSGQAHPPPQTLPRSKSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNDADYKAALCRHKQYMGNRFIQVHPITKKGMLEKIDMIRKRLQNFSYDQREMVLNPEGEVSSAKVCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKTEDDAHKSEHLHR-----KKLNGREAFVHIVTLEDMREIEKNPPAQGKKGLKIPVPGNPAVPVIPSAGMPAAGIPSAGIPSAGIPSAGMPSAGMPSAGLPAAGLPAAGLPGSGMPGSGMPGSGIPGPGIPGPGIPGPGIPGPGMPGPGIPGPGIPGPGIPGAGIPGPPMPGPAMPGPSMPGPAMPGPAMPGPAMPGPAIPGPALPGPAIPGPGIPSAGGEEHVFLTVGSKEANNGPPFNFPGNFGGPNAFGPPLPPPGLGGAFGDVRPVMPSVGNSGLPGLGLEVPGFGGAPNNISGPSGFGGIPQNFGNGPGSLNAPPGFGNGPPGLGSVPSHLSGPPAFGPGPGPGPIHIGGPPGFGASSGKPGPTIIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVIDLNDRPIGSRKVKLVLG", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :. .* : * .: .. * : .. :.: . . ... .: * . ::.: :* :: * : . * : . . * * :.. .. .* :: .: . . . .: : . :*. . * : : . :*. .: :: * :** . .:: : . . :.*. :.* . : * : *: : . . *. : :.. : :: : : ::* .* :*.*. .:. :*. * **.. : . . :: .:: * .: : .*.:: *:* ..:.. ::: . :: : . * . :*::: ::: :. : ::* *:..: :: : : :* : :* .* : . : .: . :: * . * *. :. .*. * .** : :.: : * : ** : . . * *.. ", "identical_positions": 52, "similar_positions": 188, "identity": "5.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3564", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZG1-1", "uniprot_id": "S22AN_RAT", "id": "Q9QZG1-1", "name": "Solute carrier family 22 member 23", "aln": "MAIDRRREAAGSGAGRQPAPAEENGSLPPGDAAASAPLGGRAGSGGSAEIQPLPALHPSGGPHSSCCAAAAAPSLLLLDYDGSVLPFLGGLGGGYQKTLVVLTWIPALFIGFSQFSDSFLLDQPNFWCHGAGKGTELAGATVTGRWGDMGNWTSPSATPFSTASWGTTSNRSNSS-----DTPPLPSPPGKGNNDSNCECHAWDYGIRTGLVQNVVSKWDLVCDNAWKVHVAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSVIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFIITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKKLILYLTQKNCVSPESDIKGVMPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTG---YGIHHCFARSMMGHEVK----VPLLENFYADYYTMASIALASCLAMCLVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSELQLKLAVGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAP-IIELHNQKGYFLHHIIFACCTLICIICILLLP----ESRDQNLPENIANGEHYTRQPLLSHKK-GEQPLLLTNAELKDYS-----GLHDVAAVGDGLSEGATANGMKTM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UHH2-1", "uniprot_id": "S22AN_MOUSE", "id": "Q3UHH2-1", "name": "Solute carrier family 22 member 23", "aln": "MAIDRRREAAGSGAGRQPAPAEENGSLPPGDAAASAPLGGRAGSGSSAEIQPLPALHPSGGPHSSCCAATAAPSLLLLDYDGSVLPFLGGLGGGYQKTLVVLTWIPALFIGFSQFSDSFLLDQPDFWCRGAGKGTELAGATVTGRWGDMGNWTSPSATPFSTASWGTTSNRSNSS-----DTPPLPSPPGKGNNDSNCDCHAWDYGIRTGLIQNVVSKWDLVCDNTWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSTIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFIITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKKLILYLTQKNCVSPESDIKGVMPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTG---YGIHHCFARSMMGHEVK----VPLLENFYADYYTMASIALASCLAMCLVVKFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSELQLKLAVGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAP-IIELHNQKGYFLHHIIFACCTLICIICILLLP----ESRNQNLPENIANGEHYTRQPLLPHKK-GEQPLLLTNAELKDYS-----GLHDVAAVGDGLPEGATANGMKTM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1A5C7-1", "uniprot_id": "S22AN_HUMAN", "id": "A1A5C7-1", "name": "Solute carrier family 22 member 23", "aln": "MAIDRRREAAGGGPGRQPAPAEENGSLPPGDAAASAPLGGRAGPGGGAEIQPLPPLHPGGGPHPSCCSAAAAPSLLLLDYDGSVLPFLGGLGGGYQKTLVLLTWIPALFIGFSQFSDSFLLDQPNFWCRGAGKGTELAGVTTTGRGGDMGNWTSLPTTPFATAPWEAAGNRSNSSGADGGDTPPLPSPPDKGDNASNCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTG---YGIHHCFARSMMGHEVK----VPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDS--------GMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAP-IIELHNQKGYFLHHIIFACCTLICIICILLLP----ESRDQNLPENISNGEHYTRQPLLPHKK-GEQPLLLTNAELKDYS-----GLHDAAAAGDTLPEGATANGMKAM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PAI9-1", "uniprot_id": "A0A8M1PAI9_DANRE", "id": "A0A8M1PAI9-1", "name": "", "aln": "-------------------MCETVMAVSQLDTESHAPENG--------FVTPETSKSPG----------------LLSQTDGGVLPSVGGFG-KYQKQLIVLTWIPAIFIGFSQFSDNFLLTNP---CPEPHN--------------NSSQLLTVAPTAVSTVFTGVN-----------------------TEAASQCNCTPSSYKLQNGLEQNIVTKWNLVCDSAWKIHIAKFSLLVGSIFGYLVLGVLADWFGRHPVLILSVVFLLVFGMTVAFSVNLPMFGTLRFFEGFCLAGITLSLYVLRIELCLPGWRFSITMVANFMMLAGQLLMPGLAALCRDWQILQAVIVCPLLLMLSYIWAFPESLRWLLATQQYSRSKWIMERISKKNNINLQEDAEELMTELNGALQKQPKKTCIVKMVGTRNLWKNIVVLCVNSLTG---YGIHHCFARSMMEKKTVGF--VEKLHDFYAEYYVMAVIAVASCVFLCPAVALMGRRGGLLMFMIITALASLLQLGLLNLLGKYGDHLSL--------VHSDELNDKFSVAFSIIGMFSSHAVSNLSIFFCAEITPSVIRGGGLGLVLASAGFGMLTSP-IMELHNQKGYFLHHIIFACCTLICIICILLLP----ETRNQPLPETLSDGESYTRQPLLPPRKPGEQRLLLTKSESREYARVGDTPLHEAAATVVSTMDSTASSAVDIHMLIDAPIQQEPAQVQLLSMETLTSSQGQDELKQSVEEHPKSVLGTIPNTSTPLAVNSIPKSKRPESPPHDVLAVLSSAVEDASLIIHPVPTGLPSILDSVVPPAAVGSPLEVGNEVDSIESKRPESPPDDVLAVLSSPIEDTSLTIHPVPSELPSTLDTVIPATVGSPLEVNNEEDSTDSVSPPIDLPLCALTQSNNPSSIGQSPNLLNDIPPSSSIDSHTHPVSEILPPSPTELSMLDPSSQMNAAPPIDSGTPLLQLDAPPELNSIESAPPSLSNGSTSLLAAHATSTDSDSVTESGNPLMVNSTVSSPIDSGLPSDVDIPNTANGGTSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCA0-1", "uniprot_id": "Q9VCA0_DROME", "id": "Q9VCA0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "--------------------MTQSTENPEKNRE---------------LISEES----------------------MKDLLTKQLEVVGSGG-AFVWAIFFLCVTPNILNGFHVSSYTLLGHLPDDQWCGIPELQDTNWTHAQKREIVAKGLDSGGCTVWDWNYGHLAKMSYEAALN-------YTGHLTQISPPAEVSCRVKGQHEFAHPETTFVADWDLTCDRSIQRTSAQVSISLGKFCGSFSFGILADKFGRKSSFTLGAAFFIVGSFFCTFSPWYSLFLAGRFALGAASSGLFYPAFTMIVENICLKHRSWMSIAFSASYPVGMIILAIVGYVIQPWRHLQLALTIPSLLLILNCYLMSESPRWLITNQRYDRVYKILFRQPSHYQIQPAVAAPSQVASDKKSLE--PEEGFSFGQKLKNGPLKSIIELYANSKVRRMIFASYFMFCVTSLSYYVTALNAANLSVSRYLYIIGTGLVDIPSYLVPVIMLRFTGRRLTTMFLFLWTGVSLLLVLAVP------------------------AGSTTWIVAFAMLGRFGISATYSVVTLYTAELYPTQIRNSALGTCSTFAHVGSISAPYVVDVLGALGWYIPTTICGCCVLVAGLLTLTLP----ETGTGKLSDKVESSASSTPTEPAEKQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDS2-1", "uniprot_id": "Q9VDS2_DROME", "id": "Q9VDS2-1", "name": "", "aln": "----------------MKKDNLYRGWMPNIRRNSPAPLDLGHMAHSFTCTDPKAN----------------------EVSPQTPHPKANNLADDNDDDVITHIMGNFGPWQLRSLLILFLCKIPAAWFMACILFTAPDLYPEEEYKCDTTAFGPDVNSTVSLDHCYVMVN----------------------YGESAYAMRQCRKFLYTTGFHSLTMEFDLVCLCDFFVAWSQYWHLFGLLIGGVAATKLMRVLSPRQIYRTGIWCLLMCSLLMGLVKDFSLHCGLRCLAAVSCCFMITSGQYIFGDITAGKYRVGTLILYDCFWALGLILLPGLASNAPSWQHIYLGVTLSLLVIVFLLPWTPDSPRWQLQHTKEAQLAIERTVGILLEAARTNGRMHKVSKELPQQLEELRERMLEPMPAVHWMHLWMGQRRSTFHLVAVHMALATFMVVNTGLLLHVR----SFGREHLVSNTLAMGLAEMLGCFLALHLTFNLSERKWQWAGGFAIVVGCIGSICWFLAEEDMP----------------EVYGLTLGLLMASLPQAAVACAQSMILACLGELVPMEQRSCLSFSAVTWARVWQLSAS-FLTLLRQVSPALSLSAFCLLVILGGLGTCCLV----TRDKEQPPVGAVVNKGQQLIAFT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDR9-1", "uniprot_id": "Q9VDR9_DROME", "id": "Q9VDR9-1", "name": "Solute carrier family 22 member 3", "aln": "--------------------MTDSQSMGSIPRKSSPELDVVEQVNG-------------------------------SFGRWQLRTILLIFLCKIPSAWFTAIIIYTAPYPWKGELVCHPADWNVSRSQTEHVDRNHPLWQDARSTDRLFNVDVCNAYSNSLARGFVRSHGQEWN-------------ASQSKEPGGQSSLPCEHVEHRTDYKSLISQFDLICSRRVLVALTQSFHALGALIGGLMAYSALKKISPRRLMLLGMIGQIFCGNLTGLVDTYQLHIYFRCLTSIFCALMYTSGQFILNDITSGKARIIVVTLSELFWSMGLVLLPAISIYFDNWSYLYVAISSSLIVLVWLHRWIADAPRWLLQHQRVEAALRQLLESATYNNRKVPLTLDVQLTMYANDLDQKSKQKHSYCQVWDGETKRSQLVYIHLIWGG-------AMVLYNIILLMIR----NLGAQQVHVNTAAMGFAEMVGLFVGLYLILYT-RRHWRWAGNLMIIAGLSTYLIWLLPETERN-----------------SRRVGLELVFWLILKIANSASIAVLTTCTSEIVSKEKRVVLMLSVISFSRVCLLFCP-FLSCLTVIHHLVPITILATMGWIYGLALRRLNRYYWNTEQPQISQVPTPNTYRRQSAIILRRCSTVSSDCSAYSNELLSNFERNMAVSIADIWHINFHPSSEIEMEVEQSGPEAHRAHSSETI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .. .::* * :: .* : * . .. : . :. . : :. * . . : . : : * . * .::. :. * : : . :::: .:: ** : : *. :. . . : . : . . .* : . : : : : . . : .*: . * : : . : .. .: : : : * . . ", "identical_positions": 15, "similar_positions": 83, "identity": "1.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3566", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZMY7-1", "uniprot_id": "5NTC_RAT", "id": "D3ZMY7-1", "name": "Cytosolic purine 5'-nucleotidase", "aln": "-------------------------------------------------------------------------------------------------MMTSWSDRLQN------------------------AADVPANMDKHAL-KKYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEYESLGFELTVERLVSIGYPQELLNFAYDSTFPTRGLVFDTLYGNLLKVDAYGNLLVCAHGFNFIRGPETREQYPNKFIQRDDTERFYILNTLFNLPETYLLACLVDFFTNCPRYTSCDTGFKDGDLFMSYRSMFQDVRDAVDWVHYKGSLKEKTVENLEKYVVKDGKLPLLLSRMKEVG-KVFLATNSDYKYTDKIMTYLFDFPHGPKPGSSHRPWQSYFDLILVDARKPLFFGEGTVLRQVDTKTGKLKIGTYTGPLQHGIVYSGGSSDTICDLLGAKGKDILYIGDHIFGDILKSKKRQGWRTFLVIPELAQELHVWTDKSSLFEELQSLDIFLAELYKHLDSSSNERPDISSIQRRIKKVTHDMDMCYGMMGSLFRSGSRQTLFASQVMRYADLYAASFINLLYYPFSYLFRAAHVLMPHESTVEHTHVDINEMES---PLATRNRTSVDFKDTDYKRHQLTRSISEIKPP----------NLFPLAPQEITHCHDEDDDEEEEEEE---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3V1L4-1", "uniprot_id": "5NTC_MOUSE", "id": "Q3V1L4-1", "name": "Cytosolic purine 5'-nucleotidase", "aln": "-------------------------------------------------------------------------------------------------MTTSWSDRLQN------------------------AADVPANMDKHAL-KKYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEYESLGFELTVERLVSIGYPQELLSFAYDSTFPTRGLVFDTLYGNLLKVDAYGNLLVCAHGFNFIRGPETREQYPNKFIQRDDTERFYILNTLFNLPETYLLACLVDFFTNCPRYTSCDTGFKDGDLFMSYRSMFQDVRDAVDWVHYKGSLKEKTVENLEKYVVKDGKLPLLLSRMKEVG-KVFLATNSDYKYTDKIMTYLFDFPHGPKPGSSHRPWQSYFDLILVDARKPLFFGEGTVLRQVDTKTGKLKIGTYTGPLQHGIVYSGGSSDTICDLLGAKGKDILYIGDHIFGDILKSKKRQGWRTFLVIPELAQELHVWTDKSSLFEELQSLDIFLAELYKHLDSSSNERPDISSIQRRIKKVTHDMDMCYGMMGSLFRSGSRQTLFASQVMRYADLYAASFINLLYYPFSYLFRAAHVLMPHESTVEHTHVDINEMES---PLATRNRTSVDFKDTDYKRHQLTRSISEIKPP----------NLFPLAPQEITHCHDEDDDEEEEEEE---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49902-1", "uniprot_id": "5NTC_HUMAN", "id": "P49902-1", "name": "Cytosolic purine 5'-nucleotidase", "aln": "-------------------------------------------------------------------------------------------------MSTSWSDRLQN------------------------AADMPANMDKHAL-KKYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEYESLGFELTVERLVSIGYPQELLSFAYDSTFPTRGLVFDTLYGNLLKVDAYGNLLVCAHGFNFIRGPETREQYPNKFIQRDDTERFYILNTLFNLPETYLLACLVDFFTNCPRYTSCETGFKDGDLFMSYRSMFQDVRDAVDWVHYKGSLKEKTVENLEKYVVKDGKLPLLLSRMKEVG-KVFLATNSDYKYTDKIMTYLFDFPHGPKPGSSHRPWQSYFDLILVDARKPLFFGEGTVLRQVDTKTGKLKIGTYTGPLQHGIVYSGGSSDTICDLLGAKGKDILYIGDHIFGDILKSKKRQGWRTFLVIPELAQELHVWTDKSSLFEELQSLDIFLAELYKHLDSSSNERPDISSIQRRIKKVTHDMDMCYGMMGSLFRSGSRQTLFASQVMRYADLYAASFINLLYYPFSYLFRAAHVLMPHESTVEHTHVDINEMES---PLATRNRTSVDFKDTDYKRHQLTRSISEIKPP----------NLFPLAPQEITHCHDEDDDEEEEEEEE--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FC21-1", "uniprot_id": "E7FC21_DANRE", "id": "E7FC21-1", "name": "Cytosolic purine 5'-nucleotidase", "aln": "-------------------------------------------------------------------------------------------------MTTSWSDRLQN------------------------YADIPANMDGLSM-KKYRREVHHRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEYESLGFDLTVERLVSIGYPQELLNFVYDPAFPTRGLVFDTTYGNLLKVDAYGNILVCAHGFNFLRGPEIRELYPNKFIQRGDTERFYILNTLFNLPETYLFACLVDFFTSCSRYTSCEMGFKDGDLFMSFKSMFQDVRDAVDWVHFKGSLKEKTVENLEKYVVKDAKLPLLLSRMNEVA-KVFLVTNSDYKYTDKIMTYLFDFPHGPKLGSPHRPWQSYFDLILVDARKPMFFGEGTVLRQVDTTTGRLKIGTYTGPLQHGIVYSGGSSDIVCDLLGAKGKDILYIGDHIFGDILKSKKRQGWRTFLVIPELAQELHVWTDKSSLFEELQSLDIFLAELYKHLDSSSNERPDISSLQRRIKKVTHDMDMCYGMMGSLFRSGSRQTLFASQVMRYADLYAASFINLLYYPFSYLFRAAHVLMPHESTVEHTHVDINDTES---PMATRNRHAIDFREHECKRHQLTRSISEINPP----------HLFPQTPQEITHCHDEDDDEEEEEEEE--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWV5-1", "uniprot_id": "Q9VWV5_DROME", "id": "Q9VWV5-1", "name": "", "aln": "MRNLRRLTNTLQYHRQLTSRSETTDTFRYPNHIAQVAIVNDSRRLSLKSGEIPKHGQGSQTAPSRIYPIHIGAPNCQRSRRNKGNRRLSCSYASLGRMQATPSEDAQPQDPLKSFERDFCDLPPYQCEMSDSAPNTPGPCSTSALPKKYYRYAAHRVFVNRSLHLENIKYYGFDMDYTLAEYKSPQYEQLGFNLVKERLVFMGYPKEILQFEYDPTFPVRGLWFDTLYGNLLKVDAYGNILVCVHGFEFIKHHQVYELYPNKFLKLDE-SRVYVLNTLFNLPETYLLACLVDFLTNSSDFVRVERGIKAGDLLFTYKSIFQDVRRAVDWVHSDGDLKRRTTQNMAHYVKKDERLPTVLSRIRESGAKLFMLTNSDYTYTNEIMTYLFDFPHGATPDEPHRDWKTYFDVIVVDARKPLFFDEGTVLRQVDTKTGSLKIGTHVGPLQPGQVYSGGSCELFTKFINAKGKDVLYVGDHIFGDILKSKKIRGWRTFLIVPELVRELHVWTDECQLFAELQNLDIKLGDLYRDLDSSAKVKPDISQLRTCIRDVTHKMDMSYGMMGSLFRSGSRQTFFSSQVVRYADVYAATLLNLIYYPFSYMFRAPAMLLPHESTVAHDQAHQPPPPLGPVPVPATGAASVAASPDEPAR-ILAGTAEHVKDPKDLHRASSIVHTRPSTPTVVTHTHDEDYSEEEETPSGAESSTEAVRDASED", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: *: * .: *. . :: *** * . ********* :*:** :********* ****:**.***:*. **** :***:*:*.* **.:**.*** *** ************:***.***:*:: : * *****:: .: .*.*:************:******:*... :. : *:* ***:::::*:***** ****** .*.**.:*.:*: :** ** :** :***:.* . *:*: *****.**::***********.. ...** *::***:*:******:**.**********.** *****:.**** * ******.: . .::.*****:**:************* :******::***.:*******:..** ***.*** *.:**:.****:: :****.:: *:.***.***.***************:*:***:****:***:::**:******:***. :*:****** * :.. *:.: . :: : * *: : ..:: * : * :* :** **** .**** . ", "identical_positions": 323, "similar_positions": 149, "identity": "45.43%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3568", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O14901-1", "uniprot_id": "KLF11_HUMAN", "id": "O14901-1", "name": "Krueppel-like factor 11", "aln": "MHTPDFAGPDDARAVDIMDICESILERKRHDSERSTCSILEQTDMEAVEALVCMSSWGQRSQKGDLLRIRPLTPVSDSGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTRTPVSPQVTDSKACTATDVLQSSAVVARALSGGAERGLLGLEPVP----SSPCRAKGTSVIRHTGESPAAC-FPTIQTPDCRLSDSREGEEQLLGHFETLQDTHLTDSLLSTNLVSCQPCLHKSGGLLLTDKGQQAGWPGAVQTCSPKNYENDLPRKTTPLISVSVPAPPVLCQMIPVTGQSSMLPAFLKPPPQLSVGTVRPILAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPPPAPCAANVMAAGNTKLLPLAPAPVFITSSQN-CVPQVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTGEKPFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGKLNRIASAESPGSP--LVSMPASA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K1S5-1", "uniprot_id": "KLF11_MOUSE", "id": "Q8K1S5-1", "name": "Krueppel-like factor 11", "aln": "MHSPGSTGPGDGRAADIMDICESILERKRHDSERSTCSVLEQTDIEAVEALVCMSSWGQRSQ------MRPLTPVSDSGDVTTAVLMDTAAPDLPKDFHSFSTLCITPPQSPELTEPSTGTPVPSQVVNSKGCMVTALPPSPAGGPRTLSKREP-----LEPAS----GSSCRAVMTSVIRHTGESPAPTRFPTGPTQEQRASDSGEGQERLLDHLEALQDTRLANGLLVTNLVSCQPCLHKSGGSFPTDKGQQTGWPAAVQTCLPKNPESDLSRKITPLISVPVSSPPVLCQMIPVAGQNGLFSAFLKPPTQLPAGTIKPILPQAASMSQPVFMGPPVPQGTVMLVLPQNTFPQPAACPSSVMAIGNTKLLPLAPAPVFLASSQN-CAPQVDFSRRRNYVCNFPGCRKTYFKSSHLKAHLRTHTGEKPFTCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGKLNRITLAESPGSI--LEPLPASG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5RIQ4-1", "uniprot_id": "Q5RIQ4_DANRE", "id": "Q5RIQ4-1", "name": "", "aln": "--MLNFAS--DSGRSSLVDICEVMMERNRHDSEKSCSSTPEYNDLEAAEALVCMSFWVQRTHK-----PRPLTPTSDS---CDSLALQPELIESPKDLVSLSSLCMTPPHSPSFAETSGTAVLSTSVACSGLKPHPRLCSALTNRAACHVSLHPSTTVLLNPAPPQTAEQPSLRRATSVIRHTADR----------SMDHNIPSTTTGQEKPCSSEIPPEHTESNTSLKGEVQICSSPCDS-------AEPERTAPSPDSTGIAIPTS-QSTIP-------QSPMSSPPVLCQVFPVNGQTGIISAFVQTPVQMQTSGSKPILPHS----QPLLVGSPVAQGTVMFVVPQSQVSQSSTCQQSVVTLGNTKLLPLAPAPVYVPSGQSSGVTQSDFSRRRNYVCNFQGCKKTYFKSSHLKAHLRTHTGEKPFSCHWEGCDKKFARSDELSRHRRTHTGEKKFVCPVCERRFMRSDHLTKHARRHMTTKRSTAWPNEVRDVNKMATSQAPSSIPLSVLLPASN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. *. .::**** ::**:*****:* .* * .*:**.******* * **:: *****.*** :: ::. : ***: *:*:**:***:**.:.*.* : :...*. * . : : : . *:*.. ... *******.: : : . ..: *:*: . . :.*. .* :...** :: : : * :. . *.. :. :. . .:.:******::** **..::.**::.* *: .. :***.:: **:::*..*.**:**:*:**. .. .:.* .*:: *************::.*.*. ..* **********.* **:**********************.* *:******************************:********************: ..* ** .:*::: :::*.* :*** ", "identical_positions": 211, "similar_positions": 148, "identity": "40.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3586", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68FD7-1", "uniprot_id": "FNIP1_MOUSE", "id": "Q68FD7-1", "name": "Folliculin-interacting protein 1", "aln": "MAPTLFQKLFSKRSGLGAPGRDARDPDCAFSWPLPEFDPSQIRLIVYQDCERRGRNVLFDSSVKRK-NEDTSVSKLCNDAQVKVFGKCCQLKPGGDSSSSLDSSITLSSDGKDQCPKYQGSRCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLSKVFTARTGSSICGSLNTLQDSLEFINQDSNTLKAD-SSTVSNGLLGNIGLSQFCSPRRAFSEQGPLRLIRSASFFAVHSNPMDMPGRELNEDRDSGIARSASLSSLFITPFPSPNSSLTRSCASSYQRRWRRSQTTSLENGVFPRWSVEESFNLSDESCGPNPGIVRKKKIAIGVIFSLSKDEDENNKFNEFFFSHFPLFESHMNKLKSAIEQAMKMSRRSADASQRSLAYNRILDALTEFRTTICNLYTMPRIGEPVWLTMMSGTPEKNQLCHRFMKEFTFLMENASKNQFLPALITAVLTNHLAWVPTVMPNGQPPIKIFLEKHSSQSVGMLAKTHPYNPLWAQLGDLYGAIGSPVRLARTVVVGKRQDLVQRLLYFLTYFIRCSELQETHLLENGEDEAIVMPGTVITTTLEKGEIEESEYVLITMHRNKSSLLFKESEETRTPNCNCKYCSHPVLGQNTENVSQPEREDTQDNSKELLGISDECQKISPPDCQEENAVDVQQYRDKLRTCLDTKLETVVCTGSAPADKCVLSETCLEPREESWQNKELLDSDNHTGTAMRPTGIVVEKKPPDKNVPSAFSCEVTQTKVTFLIGDSMSPDSDTELRSQAVVDQINRHHSEPLKEDRGVADKHQESK-ITKDQSEDSDTQNIVSGESCELPCWSHSDPE-SMSLFDEYFNDDS-IETRTIDDVPVKTSTDSKEYCCMLEYPKRLYTKTNKQKSELCKCIETVHQDSCNACFPQ-QDQRNSLSILVPHGDKESSDKKNAVGTEWDIPRNESSDSALGDSESEDTGPDIRRQAGGYCGGDQEDWTEEDEIPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGNDERLRQCLVSDLSHAVQHPVLDEPIAEAVCIIADMDKWTVQVASSQRRVTDNKLGKEVLVSSLVSNLLHSTLQLYKHNLSPNFCVMHLEDRLQELYFKSKMLSEYLRGQMRVHVKELGVVLGIESSDLPLLAAVASTHSPYVAQILL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TF40-1", "uniprot_id": "FNIP1_HUMAN", "id": "Q8TF40-1", "name": "Folliculin-interacting protein 1", "aln": "MAPTLFQKLFSKRTGLGAPGRDARDPDCGFSWPLPEFDPSQIRLIVYQDCERRGRNVLFDSSVKRR-NEDISVSKLGSDAQVKVFGKCCQLKPGGDSSSSLDSSVTSSSDIKDQCLKYQGSRCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLSKVFTARTGSSICGSLNTLQDSLEFINQDNNTLKAD-NNTVINGLLGNIGLSQFCSPRRAFSEQGPLRLIRSASFFAVHSNPMDMPGRELNEDRDSGIARSASLSSLLITPFPSPNSSLTRSCASSYQRRWRRSQTTSLENGVFPRWSIEESFNLSDESCGPNPGIVRKKKIAIGVIFSLSKDEDENNKFNEFFFSHFPLFESHMNKLKSAIEQAMKMSRRSADASQRSLAYNRIVDALNEFRTTICNLYTMPRIGEPVWLTMMSGTPEKNHLCYRFMKEFTFLMENASKNQFLPALITAVLTNHLAWVPTVMPNGQPPIKIFLEKHSSQSVDMLAKTHPYNPLWAQLGDLYGAIGSPVRLARTVVVGKRQDMVQRLLYFLTYFIRCSELQETHLLENGEDEAIVMPGTVITTTLEKGEIEESEYVLVTMHRNKSSLLFKESEEIRTPNCNCKYCSHPLLGQNVENISQQEREDIQNSSKELLGISDECQMISPSDCQEENAVDVKQYRDKLRTCFDAKLETVVCTGSVPVDKCALSESGLESTEETWQSEKLLDSDSHTGKAMRSTGMVVEKKPPDKIVPASFSCEAAQTKVTFLIGDSMSPDSDTELRSQAVVDQITRHHTKPLKEERGAIDQHQETKQTTKDQSGESDTQNMVSEEPCELPCWNHSDPE-SMSLFDEYFNDDS-IETRTIDDVPFKTSTDSKDHCCMLEFSKILCTKNNKQNNEFCKCIETVPQDSCKTCFPQ-QDQRDTLSILVPHGDKESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGHDMTRQVSSYYGGEQEDWAEEDEIPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGSDERFRQCLMSDLSHAVQHPVLDEPIAEAVCIIADMDKWTVQVASSQRRVTDNKLGKEVLVSSLVSNLLHSTLQLYKHNLSPNFCVMHLEDRLQELYFKSKMLSEYLRGQMRVHVKELGVVLGIESSDLPLLAAVASTHSPYVAQILL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IT71-1", "uniprot_id": "A0A0R4IT71_DANRE", "id": "A0A0R4IT71-1", "name": "", "aln": "MAPTLFHKLFNKKNPLSPPARCSRE-DTVFSWSSPELEPSQIRLIVYQDCERRGRNVLFDSDARKRSTEDGPATRVCGEAQVKMFGRCCQLRPTGGSSSSLDSSSSCASEPKEQNRFQASSRCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQMMLSKVFTARTGGSVCGSLNTLQDSLEFINQDSSTLRPEQNHTAANGFLGSIGFSQLCSPRRALSEQGPLRLIKSASFFSGHSNPMDMPGRGLYDERDSGIARSASLSSLLITPFPSPGSSLTSSCASSYQRRWLRSQTTSLENGVFPRWSVEESFNMSDESSGPSLGVARKKKIAIGVIFQLSPNEEENTKFQDFFFSHFPLFESHMNKLKSAIEQAMILSRRSADANQRALAYSRMVDGLNEFRTTICNLYTMPRVPEPVWLTMMSGPPEKNQLCGHFMRELALLMEQASKNQFLPALLTAVLTNHLAWVPTVMPNGQPPIQIFLEKHSSQSVDMLAKTHPYNPLWAQLGDLYGAIGSPVRLSRTVVVGRRQELVQRLLYLLTYFIRCSELLETHLLESAEDEAIVMPGSLITTSLRRGEVEESEYVLVTMHK---------------------------------------------PSRDYLSQGDKSDPANPDEHQTEHTSDVPVCRVADSPLFDTRLETLVKVGSTSPSERRASVEVQEAQAEAGGVPIRIHHPSDS---------LLEKKPPDK----SFPDIEPSAKVTFLIGDSMSPESDLESRQQKVEQEIRRHKQKLLRDAQQTNTENKLQVDQIKSKSRE-----FVTG---RTPRWSASAQEDCVDMFEEYFSEDNPVQTLTIDDVYGKHAPKDK-------------------SDVQLECVR-VDAGCCKSCSSADLDKGIEISLSVPSAVEQ---KKAAPLNDWEIPRNESSDSALGDSESEDAGPDLPRADP--DGAFDSDFQDELELPLPGAKLVEN-YSKPSIANFGRSLFGGYCPSYVPDFVLQGVPNDEKLKQNLVSDLAHAVQHPVLDEPIAEAVCIIADTEKWTVTVASSQRRSSE-KLGKEVLVSSLVSGLLQSTLQLYRLNLSPNFCIMHLEDRLQELYFKSKMLAEYLRGQTRVHVKELGMVLGIESNDLPLLAAIASTHSPHVAQILL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:***.*:. *..*.* :*: * ***. **::***********************..::: .** ..::: .:****:**:****:* *.******** : :*: *:* .*************************************:***********.*:*****************..**:.: . *. **:**.**:**:******:*********:*****: ********** * ::**************:*******.**** ********** ****************:*****:****.**. *:.***********.** :*:**.**::************************ :*******.**:***.*::*.*.**************: **********.****:** :**:*:::***:**********:**********************:***********.****************************:******:**::******:********** ******..*********::***:*.:**:*******:***: *:: *. .*:.: .* : * *:: ** * . :*::***:* .**.. .: * *. *: :. ..: ::******* :*. ..:************:** * *.* * ::* **: : *:: : . ::: *.:* : :*: . * *. * * .:.:*:***.:*. ::* ***** * :...* .. :*:. * ..*::* . *: :*: ** . :: ** * .:*:******************:* *: * *. :.*: :* *:*:**:**:* :*.********:****.**********: .**:::* *:***:********************* :**** ******* :: *************.**:******: *******:*****************:****** ********:******.*******:******:******", "identical_positions": 716, "similar_positions": 224, "identity": "61.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3587", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LRV2-1", "uniprot_id": "A0ABK0LRV2_RAT", "id": "A0ABK0LRV2-1", "name": "Switch-associated protein 70", "aln": "MGGLKDELLKAIWHAFTALDLDRSGKVSKSQLKVLSHNLCTVLKVPHDPVALEEHFRDDDEGPVSNQGYMPYLNKFILEKVQDNFDKIEFNRMCWTLCVKKNLTKSPLLITEDDAFKVWVIFNFLSEDKYPLIIVPEEIEYLLKKLTEAMGGGWQQEQFEHYKINFDDNKDGLSAWELIELIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHKRKNWTERWFVLKPNIISYYVSEDLKDKKGDIMLDENCCVESLPDKDGKKCLFLIKCFDKTFEISASDKKKKQEWIQAIHSTIHLLKLGSPPPHKEARQRRKELRRKLLAEQEELERQMKELQAANENKQQELESVRKKLEEAASRAADEEKKRLQTQVELQTRFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLAQQQAIQTTEAEKQELEQQRVLKEQALQEAMAQLEQLELERKQALEQYEGVKRKLEMATNTTKSWKDKVAHHEGLIRLIEPGSKNPHLITNWGPAAFTQAELEEREKSWKEKKTTD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6A028-1", "uniprot_id": "SWP70_MOUSE", "id": "Q6A028-1", "name": "Switch-associated protein 70", "aln": "MRGLKDELLKAIWHAFTALDLDRSGKVSKSQLKVLSHNLCTVLKVPHDPVALEEHFRDDDEGPVSNQGYMPYLNKFILEKVQDNFDKIEFNRMCWTLCVKKNLTKSPLLITEDDAFKVWVIFNFLSEDKYPLIIVPEEIEYLLKKLTEAMGGGWQQEQFEHYKINFDDNKDGLSAWELIELIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHKRKNWTERWFVLKPNIISYYVSEDLKDKKGDILLDENCCVESLPDKDGKKCLFLIKCFDKTFEISASDKKKKQEWIQAIYSTIHLLKLGSPPPHKEARQRRKELRRKLLAEQEELERQMKELQAANENKQQELESVRKKLEEAASRAADEEKKRLQTQVELQTRFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEAEKQELEQQRVMKEQALQEAMAQLEQLELERKQALEQYEGVKKKLEMATHMTKSWKDKVAHHEGLIRLIEPGSKNPHLITNWGPAAFTQAELEEREKSWKEKKTTE----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UH65-1", "uniprot_id": "SWP70_HUMAN", "id": "Q9UH65-1", "name": "Switch-associated protein 70", "aln": "MGSLKEELLKAIWHAFTALDQDHSGKVSKSQLKVLSHNLCTVLKVPHDPVALEEHFRDDDEGPVSNQGYMPYLNRFILEKVQDNFDKIEFNRMCWTLCVKKNLTKNPLLITEEDAFKIWVIFNFLSEDKYPLIIVSEEIEYLLKKLTEAMGGGWQQEQFEHYKINFDDSKNGLSAWELIELIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHRRKNWTERWFVLKPNIISYYVSEDLKDKKGDILLDENCCVESLPDKDGKKCLFLVKCFDKTFEISASDKKKKQEWIQAIHSTIHLLKLGSPPPHKEARQRRKELRKKQLAEQEELERQMKELQAANESKQQELEAVRKKLEEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEAEKQELENQRVLKEQALQEAMEQLEQLELERKQALEQYEEVKKKLEMATNKTKSWKDKVAHHEGLIRLIEPGSKNPHLITNWGPAAFTEAELEEREKNWKEKKTTE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LYE0-1", "uniprot_id": "Q1LYE0_DANRE", "id": "Q1LYE0-1", "name": "Switch-associated protein 70", "aln": "MG-LRDELLKAIWHAFTALDVDKSGKVSKSQLKVLSHNLCTVMKIPHDPVALEEHFRDDDEGPVSNQGYMPYLNRFILDKVQDNFDRIDFNRMCWTLCARKNLNRNHLLISDDDAFKIWCIFNFLSEDKYPLVMVSEEIEYFLRKLTEAMGGSWIEEKFEQYKLQLSSKHQCLKVWELIELVGMGHFSKGMDRQTLSMGITEVFHELILDVLKQGYMMKKGHKRKNWTERWFLLKPSLISYYVSEDLTEKKGDILLDGNCCVESLPDKEGKKCLFYVKCSDKSFEISASDKKKKQEWIQAIQTCITLLKVGRPAPHHEARQKRRELRQKQQAEQEELELRMRELQMANENKQRELEAMRKKLEEAAANAADEERRRLQTQNELQDLYRLEMEKEKMVRQQMEEQVAQKSNELEQYLQRVRELENMYHSLEEALEEERQARQDEETVRKLQARLLEEEVSKRAELEEIHLYQQQTISQTQAEKQELERERLAKESALESAMQQLHQLEADRQGALEQYQEVMKKLSDAANNTKSWKDKVAQHEGLIRLIQPGPKYPQKITNWGPAAFTDAELNLREKDWQEKKNRPATPQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *::************** *:*******************:*:*****************************:***:*******:*:*********.:***.:. ***:::****:* ************::*.*****:*:********.* :*:**:**:::...:: *..******:* *:*********:**.*.***:*****************:*********:***.:*********.:*****:** **********:****** :** **:****************** : * ***:* *.**:****:*:***:* ******* :*:*** ***.**:***::********:.**:**::***** *** : *:*:**::************.*************:** .*:****:********************** *******: ** ***:*. *:*******.:*: **.**:.** **.*** :*: *****: * :**. *:: *********:********:**.* *: **********:***: ***.*:***. ", "identical_positions": 435, "similar_positions": 108, "identity": "73.85%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3606", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHV2-1", "uniprot_id": "MACF1_RAT", "id": "D3ZHV2-1", "name": "Microtubule-actin cross-linking factor 1", "aln": "----------------------------------------------------MSSSDEETLSERSCRSERSCRSERSYRSERSGSLSPCPPGDTLPWNLPLHEQK--KRKSQDSVLDPAER----------AVVRVADERDRVQKKTFTKWVNKHLMKVRKHIN----------------DLYEDLRDGHNLIS----------------------------------------LLEVLSG-------------IKLPREKGR--------------------MRFHRLQNVQIALDFLKQRQ----------VKLVNIRNDDITDGNPKLTLGLIWTIILH-------------FQISDIYISGESGDMSAKEKLLLWTQKVTAGYTGIKCTNFSSCWSDGKMFNALIHRYRPDLVDMERVQIQSNRENLEQAFEVAERLG-VTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPKVPEGGEGISATEVDSRWQEYQSRVDSLIPWIRQHTILMSDKSFPQNPVELKALYNQYIHFKETEILAKEREKGRIKELYKLLEVWIEFG-RIKLPQGYHPNHVEEEWGKLIVEMLEREKSLRPAVERLELLLQIANKIQNGALNCEEKLTLAKNTLQADAAHLESGQPVQCESDVIMYIQECEGLIRQLQVDLQILRDEKYYQLEELAFRVMRLQDELVTLRLECTNLYRKGHFTSLELVPP------STLTTTHLKAEPLNKTTHSSSTSWFRKPMTRTELVAISSSEDEGSLRFVYELLSWVEEMQMKLERAEWGNDLPSVELQWETQQHIHTSVEELGSSVKEARLYEGKMSQNFHTSYVETLGKLETQYCKLKETSSFRMRHLQSLHKFVSKATAELIWLNGKEEEELACDWSDSNPNISAKKAYFSELTMELEGKQDVFRSLQDTAELLSLENHPAKQTVEAYSAAVQSQLQWMKQLCLCVEQHIKENAAYFQFFSDARDLESFLRNLQDSIKRKYTCDHNTSLSRLEDLLQDSMDEKEQLIQSKSSVASLVGRSKTIVQLKPRNPDHVLKSTLSVKAICDYR-QIEITICKNDECVLEDNSQRTKWKVISPTGNEAMVPSVCLLIPPPNTEAIDVASRVEQSYQKVMALWHQLHINTKSLISWNYLRKDIDAVQTWNLEKLRSSAPGECHQVMKNLQAHYEDFLQDSHDSALFSVADRLRIEEEVEACKTHFQQLMESMENEDKEETLAKVYISELKNIRLRLEECEQRLLKQIQSSASSKTDRDARQDVALRIAEQEHVQEDLKHLRSDLDAVSVKCTTFLQQSPSGSSATTLRSELNLMVEKMDHVYGLSIVCLNKLKTIDVIVRSIQDAELLVKGYEIKLSQEEAVPADLSALESHRTTLQHWLSDVKDKNSVFSVLDEEISKAKAVAEQLHHRAAEPNLDLERYQEKGSQLQERWHRVIAQLETRQSEVESIQEVLRDYRACHGTLIKWIEETTAQQEMMK---------------------------------------------------------------------------------PGQAEDSRVLSEQLSQQTELFAEIE------------------------------------------------------------------------RNQTKLDQCQKLSQQYSTTVKDYELQLMTYKAFVESQQKSPGKRRRMISSSDAITQEFMDLRT-------------------------------------RYTALVTLTTQHVKYISDALRRLEEEEKVVEEEKQEHVEKVKDLLGWVSTLARNTQGTTTSSRTSAS-------------------------------------------------------TDIEKAILEQQVLAEELTTKKEQVSEAIKTSQIFLA-KHGHKLSEREKEQISEQLCALNKTYHDLCDG------------------------------------------------------SANQLQQLQSELAQ-------------------------------QTEQK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLQKQQDTCHKKLEDLRSWVRQAERALERHRGRASQQELSALQQN-QSDLKDLQGDIQN----------HSTSFATAVKDIEGFLEENQNKLSPQELTALREKLYQAKEQYEG-------------------------------------------------------------LQDRTREAQKELEEAVTSALQQETEKSKAATELAENRRKIDALLDWVTSVGSSDRQPQ-TSLPGTEQFSGACLEKQTLDATDGC--VDVNQVPEKLDRQYELMKARHQELLSQQQNFIVATQSAQSFLDQHSHNLTPEERQMLQEKLGELKEQYAASLAQSEAKLRQTQTLRDELQKFLQDHREFENWLERSENELDGMHTGGSSPEALNSLLKRQGSFSEDVISHKGDLRFVTISGQKVLETENNFEEGQ---------------EPSPTRNLVNEKLKDATERYTTLHSKCTRLGSHLNMLLGQYQQFQSSADSLQAWMLTCEASVEKLLSDTVASDPGILQQQLATTKQLQEELAEHQVPVEKLQKAAHDLMDIEG--EPSLDCTPIRETTESIFSRFQSLSCSLAERSALLQKAIAQSQSVQESMESLLQSMKEVEQNLEG-EQVAALSSGLIQEALANNMKLKQDIARQKSSLEATREMVTRFMETAD-GNSAAVLQDRLAELSQRFHRLQLQQQEKESGLKKLLPQAETFEQLSSKLQQFVEHKNRLLASGNQPDQDIAHFSQHIQELTLEMEDQKENLGTLEHLVTALGSCGFALDLSQHQEKIQNLKKDFTELQKTVQEREKDASNCQEQLDEFRKLIRTFQKWLKETEGNVP-PAETFVSAKELEKQIEHLKGLLDDWAGKGVLVEEINTKGTALESLIMDITAPDSQAKTG-----------------------------SVLPSVGSSVGSVNGYHTCKDLTEIQCDMSDVNSKYDKLGDALRERQESLQTVLSRMEEVQKEASSVLQWLESKEEVLKGMDASLSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLEAYPNSQEAENWRKMQEDLNSRWEKATEVTVARQKQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLSIDPNMLNAQKQQVQFMLKEFEARRQQHEQLTEAAQGILTGPGDVSPSAS----QVHKDLQSISQKWVELTDKLNSRSTQIDQAIVKSTQYQDLLQDLSEKVKAVGQRLSGQSAISTQPDAVKQQLEETSEIRSDLGQLDDEMKEAQTLCQELSLLIGEQYLKDELKKRLETVALPLQGLEDLAADRMNRLQAALASTQQFQQMFDELRTWLDEKQSQQAK--NCPISAKLERLQSQLQENEEFQKNLNQHSGSYEVIVAEGESLLLSVPPGEEKKTLQNQLVELKSHWEDLNKKTVDRQSRLKDCMQKAQKYQWHVEDLVPWIKDCKSKMSELQV-TLDPVQLESSLLRSKAMLNEAEKRRSLLEILNSAADILINSSEIDEDEIRDEKAGLNQNMDAITEELQAKTGSLEEMTQRLKEFQESFKNIEKKVEGAKHQLEIFDALGSQACSNKNLEKLKAQREVLQALDPQVDYLRDFTRGLVEDAPDGSDASP-----LVHQAELAQQEFLEVKQRVNSSCLTMENKLEGIGQFHCRVREMFSQLADLDDELDGMGAIGRDTDSLQSQIEDIRLFLNKIQALRLDIEDSEAECRKMLEEEG-TLDLLGLKRELEALNKQCGKLTERGKARQEQLELTLGRVEDFYSKLKALNDAATAAEEGEALQWIVGTEVDVINQQLADFKMFQKEQVDPLQVKLQQVNGLGQGLIQSAGKTCDVQGLEHDMEEVNTRWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLTDTEELIANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQAAELADREKITGQLESLECRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTAKIHQQIIRHKALEEEIENHAADVQQAVKIGQSLSSLICPAEQGIMSEKLDSLQARYSEIQDRCCRKASLLEQALFNARLFGEDEVEVLNWLAEVEDKLSAVFVKDYRQDVLQKQHADHLALNEEIINRKKNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFHSTYEELTGWLREVEEELAASGGQSPTGEQIPQFQQRQKELKKEVMEHRLVLDTVNEVSHALLELVPWRAREGLDKLVSDANEQYKLVSDTVGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRGEIFSTCGE-EQKAVLQEKTECLIQQYEAVSLLNSERYARLERAQVLVNQFWETYEELSPWAEETLALIAQLPPPAVDHEQLRQQQEEMRQLRESIAEHKPHIDKILKIGPQLKELNPEE-GKMVEEKYQKAENMYAQIKDEVRQRALALDEAVSQSAQIAEFHDKIEPMLETLENLSSRLRMPPLIPAEVDKIRECISDNKSATMELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWEDIKARSEEREIKFLDVLELAEKFWYDMAALLTTIKDTQEIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGETEKPEVKKSIDEMNNAWENLNRTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIRLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMGWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSAG-DDASSLRSRLETMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEEFLLELNRMESQLSASKPTGGLPETAREQLDAHMELHSQLRAKEEIYNQLLDKGRLMLLSRGDSGSG---SKTEQSVALLEQKWHVVSSKVEERKSKLEEALSLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNTVLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEIS---NDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLADDAQKLDNLLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIESSRDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEEFRDTVHMLLEWLSEAEQTLRFRGALPDDTEALQSLIDTHKEFMKKVEEKRVDVNAAVAMGEVILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQEPIPQNIDRVKALITEHQSFMEEMTRKQPDVDRVTKTY-----KRKNIEPTHAPFIE-------KSRSGSRKSLNQPTP------------PPMPILSQSEAKNPRINQLSARWQQVWLLALERQRKLNDALDRLEEL----KEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAALHPNKDAYRPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYR------FGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDP--------------------------------CRARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASP-------------------------TRSSSSASQSNHSCTSMPSSPATPASGTKVISST----------------------------------GSKLKRPTPTFHSSRTSLAGDTSNSSSPASTGAKTNRADPKKSASRPG-------SRAGSRAGSRASSRRGSDASD-FDLLETQSACS------------------DTSESSAAGGQGSSRRGLTKPSKIPTMSKKTTTASPRTPCPKR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXZ0-1", "uniprot_id": "MACF1_MOUSE", "id": "Q9QXZ0-1", "name": "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4", "aln": "----------------------------------------------------MSSSDEETLSERSCRSERSCRSERSYRSERSGSLSPCPPGDTLPWNLPLHEQK--KRKSQDSVLDPAER----------AVVRVADERDRVQKKTFTKWVNKHLMKVRKHIN----------------DLYEDLRDGHNLIS----------------------------------------LLEVLSG-------------IKLPREKGR--------------------MRFHRLQNVQIALDFLKQRQ----------VKLVNIRNDDITDGNPKLTLGLIWTIILH-------------FQISDIYISGESGDMSAKEKLLLWTQKVTAGYTGVKCTNFSSCWSDGKMFNALIHRYRPDLVDMERVQVQSNRENLEQAFEVAERLG-VTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPKVPEGGEGISATEVDSRWQEYQSRVDSLIPWIRQHTILMSDKSFPQNPVELKALYNQYIHFKETEILAKEREKGRIKELYKLLEVWIEFG-RIKLPQGYHPNHVEEEWGKLIVEMLEREKSLRPAVERLELLLQIANKIQNGALNCEEKLTLAKNTLQADAAHLESGQPVQCESDVIMYIQECEGLIRQLQVDLQILRDEKYYQLEELAFRVMRLQDELVTLRLECTNLYRKGHFSSLELVPP------STLTTTHLKAEPLNKTTHSSSTSWFRKPMTRTELVSISSSEDEGNLRFVYELLSWVEEMQMKLERAEWGNDLPSVELQLETQQHIHTSVEELGSSVKEARLYEGKMSQNFHTSYVETLGKLETQYCKLKETSSFRMRHLQSLHKFVSRATAELIWLNGKEEEELACDWSDSNPNISAKKTYFSELTMELEGKQDVFRSLQDTAEVLSLENHPAKQTVEAYSAAVQSQLQWMKQLCLCVEQHVKENAAYFQFFSDARDLESFLRNLQDSIKRKYTCDRSTSLSRLEDLLQDSMDEKEQLIQSKSSVASLVGRSKTIVQLKPRNPDHVLKSTLSVKAICDYR-QIEITICKNDECVLEDNSQRTKWKVISPTGNEAMVPSVCFLIPPPNKEAIEMASRVEQSYQKVMALWHQLHINTKSLISWNYLRKDLDTVQTWSLEKLRSLAPGECHQVMKNLQAHYEDFLQDSHDSALFSVADRLRIEEEVEACKAHFQHLMKSLENEDKEETLAKVYISELKNIRLLLEECEQRLLKQIQSPASSKTDRDARQDITLRIAEQEHTQEDLQHLRSDLDAISMKCNVFLQQSPSGSSATTLRSELNLMVEKMDHVYGLSTVYLNKLKTIDVIVRSMQDAELLVKGYEIKLSQEEAVPADLSALESHRTTLQHWLSDVKDKNSVFSVLDEEITKAKKVAEQLRHPASEPNLDLERYQEKGSQLQERWHRVIAQLETRQSEVESIQEVLRDYRACHGTLIKWIEETTAQQEMMK---------------------------------------------------------------------------------PGQAEDSRVLSEQLSQQTELFAEIE------------------------------------------------------------------------RNQTKLDQCQKFSQQYSTIVKDYELQLMTYKAFVESQQKSPGKRRRMISSSDAITQEFMDLRT-------------------------------------RYTALVTLTTQHVKYISDALRRLEEEEKVVEEEKQEHVEKVKDLLGWVSTLARNTQGTTTSSHTSAS-------------------------------------------------------ADIEKAILEQQVLAEELTTKKEQVSEAIKTSQIFLA-KHGHKLSEGEKEQISEQLRVLNKTYHDLCDG------------------------------------------------------SANQLQQLQSELAQ-------------------------------QTEQKGCRAVAGVIDLGTVEIFPIFRAMQKGLIDQDTGLVLLES--------------------------------------------------QIIMSGLIDPENSEKLSLEEGLTRNFINLPIYQQLLGLRDSLSLV-SRLTGTLGSLSVVEAIEKKIISERLGLKVLEVH----LATGGFSLPPSENCINLEEAFHQGFIASSLHSELQSHLRSSKNLIDPNTAEKVGLLDLMQRCIIHQESGLKLLPVKQLAGGMVSLKSGRKVSIFRAVQEGLIDRQVTVRLLEAQLFAGGIVDPRTGHRLTVEEA------VRHNLIDQDMACAILIRQLQTGGIIDTVTGDRMTIDEAVTNNLVAAKIALVILESLWSFMGLLLPESGEILPITDALEQGIVSTELAHKILH------------------------------------------NRQQIEALFLPTLTEIWSWEKATESGILDKDLVNNLRSVCIPDMMPHIQLADSAEQSKVGFAAGKPPVSGPREEGSSHGE--------------------------------------------------------------KLLFQLMTHSYIHAHTGQRLLLLDQELVEMLTSRDDCQ-----------------------------------------------------------------------------------------------VILPEVFEIQHQRLNTSEALQELYTGTISQISSAKHPRKPCESQFLSQNKDYPSQENCTEAKGERSVVGIEC--------------------------------------------------------------------SPAESPERELFLKEQEAIIENVGSLKVINKVKLKLQRPLLGSRKEEQAETLREENISGDPLLVECPEESEGKDLSTEKSKCQTPT----------------KCSFTCHKEQVKTIKDIPSETGTSLIKSQNQMSQFQVDTSVGLRSEFKSEHDMNVNSLEKE--LKEELLVKDGHKQSQEGQSVADG--------------QTVALEKTDTEDNADEPALLHSS---PFEDATLSTLSAQLQDGGIFNEETGQKLLLNEAIAQGLVS---SHTAVKLMGKLNMFRGFFDSQ---------TCESLTTEEVIDEGLMDEKLLYNVLMSDKAISG---------ILDPRTHSLCSVKEAVAAGLLDKETATRILEGQVITGGIVDLKRGKKLSVTLASNLGLVDTADQTELINL--------EKATKGRGAEKAVKERLIELQMETAGLMDPESKAPLTVL-----------QSIDRGILEREAAVYLLTKQVLDGGIIHHISGLRLSVDNAFKHGLIGEDMARQLRKV----------------------------------------------------------------------------------------------------ENFIHYQFFHPQTKEALSFSEAIKLDLVSPDLKREIQEIQDFSGNLGDFIYGQKLTLAKTNKEESLANKTELPSGVMHGVIDPENCTIIPYSELVKKCRIDTESGWRYLEVIPFSDI-----------------KDEAGNNVLTPPEAIQLGKVDFASALKVLEAQANTGGIIDMATGKRVTLASALEKKLLDENMARIIASHQMLSGGIIDIYSDQRVTLNDAVEKRLISPELAAMIQVDP--------------------------------------------------------------------------------------LAEQGGTGVCELKGDFLRKELLSESSKTPRESY-SKEKH---------EAVLQAGSLCAPEKAGIRGSNGEKAEKGRKISVEME--------------------GQRQDEKA--SSDSKVSASILSPFGFEGESSYQVSVTHPCSE---------------SCDLKPREETRSCMKKCAVVERDKVVTQIKMVSHVKQS------------------------TSGLDAEEARERQGRMVSKEQGSHYETAGNLLSERSVRVDRRVRREMGGEQSVQMSRE------AAVLSEEESDQEVTIGDEPDSFVKSQSMKM-------------------------------------IGNDKGKEAGIEKDISVVCKIEGFPSQMTSKDASLTNQDALPFYT-----EGETKTVNLCSILKPGEKLSQETASTVQKEPLSSEIPRPERLNSQESDEEPQISDVPHISKGDMAAQITTRQETTDVQDLYITSK------------------SSETKDKIFPSKNYIEKLHQEIPMDPTRSHKLKEATISTLETEGISYLDSSDIKSLCED-SKADHKSCGHQKSKVTTTQAK--KSLEVVDLLVRDTEEGSSEDRVGQRGPRVLASLLPEKLPTRTVQSENIRQHDAVI-----------PAISEIREEMALSLPCSVVKVDGKIPKEKHKEILGDEQGPFMAIPSGK-----------------------------------------GIEGVNPEPCRATQNVFTRRLCLEHDEKLVSYLSLLRDIEMRTKQIQPLEL--NVAELQDLLGQAKELDRELKDLSTVVSQELECVDRIVISQPQEVPAQLLKALEKDAKNLQKSLDSVSDSWSSRFLHLQSAVEVKKATVLNRHKELQGKLQDLRAWVGRASLTLNSKGCDTETDADSLSHTLQPYKDMKQSMAERKSQLDALALDIQ------------LFISEHPQDLSLQQNQEMLQFLSELQRSFQGLVEHTAAQKDVVQGHLQQVQQEVQVK-------------------TLQKQQDTCHKKLEDLCNWVGQAERALERHQGGSSSGKSSLLCAEPKVDLKDLQGDIQS----------HSTSFATAVKDIEGFLEENQTKLSPQELTALREKLHQAKEQYEV-------------------------------------------------------------LQERTRVAQKELEEAVTSALQQETEKSKAATELAENKRKIDALLDWVGLLWGHLRESHRLAFQEWSSSLELAMEKQTLAATDGH--VDVNQVPETLDRQYELMKARHQELLSQQQNFIVATQSVQSFLDQHSHNLTPEERQKLQEKLGELKEQYAASLARSEAELKQTQALRDELQKFLQDHKEFENWLQQSENELDSMHKGGSSPEALNSLLKRQGSFSEDVISHKGDLRFVTISGQKVLETENNFEEGQ---------------EPSATRNLVNEKLKDATERYTTLHSKCIRLGSHLSMLLGQYQQFQSSADSLQAWVLTCEASVGKLLSDTVASDPGVLQQQLATTKQLQEELAEHQVPVEKLQKAAHDLLDIEG--EPALDCRPIQETTDSISSRFQNLSCSLDERSALLQKAIAQSQSVQESMESLLQSIREVEQNLER-DQVASLSSGVIQEALANNMKLKQDIARQKSSLEATHDMVTRFMETAD-SNSASVLQGKLAELSQRFQQLQLQQQEKESNLKKLLPQAEMFEQLSNKLQQFMENKSRLLASGNQPDQDIAHFSQQIQELTLAMEDQKENLDTLEHLVTTLGSCGFALDLSQHQDKIQNLKKDFTELQKTVQEREKDASTCQEQLDEFRKLIRTFQKWLKETEGNVP-PAKTFVSAKELEKQIEHLKDLISDWESKGALLGEINAKGTALESLIMDITAPDSQAKTG-----------------------------SILPPVGSSVGSVNGYHTCKDLTEIQCDMFDVNSKYEKLWEVLRERQESLQTVFSRMEEVQKEASSVLQWLESKEEVLKAMDATLSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLKTYPNSQEAENWKKMQEDLNSRWEKATEVTVARQKQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLSIDPNML---KQQVQFMLKEFEARRQQHEQLNEAAQGILTGPGDMSPSAS----QVHKDLQSISQKWVELTDKLNSRSSQIDQAIVKSTQYQDLLQDLSEKVKAIGQRLSGQSAISTQPEAVKQQLEETSEIRSDLGQLDNEIKEAQTLCQELSLLIGEQYLKDELKKRLETVALPLQGLEDLAADRMNRLQAALASTQQFQQMFDELRTWLDEKQSQQAK--NCPISAKLERLQCQLQENEEFQKNLNQHSGSYEVIVAEGEALLLSVPPGEEKKTLQNQLVELRSHWEDLSKKTANRQSRLKDCMQKAQKYQGHVEDLVPWIDECKSKMSELQV-TLDPVQLESSLLRSKAMLNEAEKRRSLLEILNSAADILINSSEIDEDEIRDEKAGLNQNMDAITEELQAKTSSLEEMTQRLKEFQESFKNIEKKVEGAKHQLEIFDALGSQACSNKNLEKLKAQQEVLQALEPQVDYLRNFTQGLVEDAPDGSDASP-----LVHQAEVAQQEFLEVKQRVSSSCLTMENKLEGIGQFHCRVREMFSQLADLDDELDGMGAIGRDTDSLQSQIEDVRLFLNKIQALRFDIEDSEAECRKMLEEEG-TLDLLGLKRELEALNKQCGKLTERGKVRQEQLELTLGRVEDFYRKLKALNDAATAAEEGEALQWIVGTEVDVINQQLADFKLFQKDQVDPLQVKLQQVNGLGQGLIQSAGKNCDVQGLEHDMDEINTRWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLTDTEELIANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQLESLERRWTDLLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTANKLANSEPVGTQTAKIHQQIIRHK-------------------------------------------------------------------------------------------------------------ALNEEIINRKKNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKTRYADITLTSSKALRTLEQARQLATKFHSTYEELTGWLREAEEELAASGGQSPTGEQIPQFQQRQKELKKEVMEHRLVLDTVNEVSHALLELVPWRAREGLDKLVSDANEQYKLISDTVGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRGEIFSTCGE-EQKAVLQEKTECLIQQYEAVSLLNSERYARLERAQVLVNQFWETYEELSPWAEETLALIAQLPPPAVDHEQLRQQQEEMRQLRESIAEHKPHIDKILKIGPQLKELNPEE-GKMVEEKYQKAENMYAQIKDEVRQRALALDEAVSQS---AQFHDKIEPMLETLENLSSRLRMPPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWEDIKARSEEREIKFLDVLELAEKFWYDMAALLTTIKDTQDIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGETEKPEVKKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVATVNKAGSELLESSAG-DDASSLRSRLETMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELNRMENQLSASKPTGGLPETAREQLDTHMELHSQLRAKEEIYNQLLDKGRLMLLSRGDSGSG---SKTEQSVALLEQKWHAVSSKVEERKSKLEEALSLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNTVLSQIEEHKVFANEVNDHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEIS---NDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLAGDTQKLDNLLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIEGSRDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEEFRDTVHMLLEWLSEAEQTLRFRGALPDDTEALQSLIDTHKEFMKKVEEKRVDVNTAVAMGEAILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQEPIPQNIDRVKALITEHQSFMEEMTRKQPDVDRVTKTY-----KRKSVEPTHAPFME-------KSRSGSRKSLNQPTP------------PPMPILSQSEAKNPRINQLSARWQQVWLLALERQRKLNDALDRLEELCPELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAALHPNKDAYRPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDP--------------------------------CRARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASP-------------------------TRSSSSASQSNHSCTSMPSSPATPASGTKVISSS----------------------------------GSKLKRPTPAFHSSRTSLAGDTSNSSSPASTGAKANRADPKKSASRPG-------SRAGSRAGSRASSRRGSDASD-FDLLETQSACS------------------DTSESSAAGGQGSSRRGLTKPSKIPTMSKKTTTASPRTPGPKR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPN3-1", "uniprot_id": "MACF1_HUMAN", "id": "Q9UPN3-1", "name": "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5", "aln": "----------------------------------------------------MSSSDEETLSERSCRSERSCRSERSYRSERSGSLSPCPPGDTLPWNLPLHEQK--KRKSQDSVLDPAER----------AVVRVADERDRVQKKTFTKWVNKHLMKVRKHIN----------------DLYEDLRDGHNLIS----------------------------------------LLEVLSG-------------IKLPREKGR--------------------MRFHRLQNVQIALDFLKQRQ----------VKLVNIRNDDITDGNPKLTLGLIWTIILH-------------FQISDIYISGESGDMSAKEKLLLWTQKVTAGYTGIKCTNFSSCWSDGKMFNALIHRYRPDLVDMERVQIQSNRENLEQAFEVAERLG-VTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPKVPEGGEGISATEVDSRWQEYQSRVDSLIPWIKQHTILMSDKTFPQNPVELKALYNQYIHFKETEILAKEREKGRIEELYKLLEVWIEFG-RIKLPQGYHPNDVEEEWGKLIIEMLEREKSLRPAVERLELLLQIANKIQNGALNCEEKLTLAKNTLQADAAHLESGQPVQCESDVIMYIQECEGLIRQLQVDLQILRDENYYQLEELAFRVMRLQDELVTLRLECTNLYRKGHFTSLELVPP------STLTTTHLKAEPLTKATHSSSTSWFRKPMTRAELVAISSSEDEGNLRFVYELLSWVEEMQMKLERAEWGNDLPSVELQLETQQHIHTSVEELGSSVKEARLYEGKMSQNFHTSYAETLGKLETQYCKLKETSSFRMRHLQSLHKFVSRATAELIWLNEKEEEELAYDWSDNNSNISAKRNYFSELTMELEEKQDVFRSLQDTAELLSLENHPAKQTVEAYSAAVQSQLQWMKQLCLCVEQHVKENTAYFQFFSDARELESFLRNLQDSIKRKYSCDHNTSLSRLEDLLQDSMDEKEQLIQSKSSVASLVGRSKTIVQLKPRSPDHVLKNTISVKAVCDYR-QIEITICKNDECVLEDNSQRTKWKVISPTGNEAMVPSVCFLIPPPNKDAIEMASRVEQSYQKVMALWHQLHVNTKSLISWNYLRKDLDLVQTWNLEKLRSSAPGECHQIMKNLQAHYEDFLQDSRDSVLFSVADRLRLEEEVEACKARFQHLMKSMENEDKEETVAKMYISELKNIRLRLEEYEQRVVKRIQSLASSRTDRDAWQDNALRIAEQEHTQEDLQQLRSDLDAVSMKCDSFLHQSPSSSSVPTLRSELNLLVEKMDHVYGLSTVYLNKLKTVDVIVRSIQDAELLVKGYEIKLSQEEVVLADLSALEAHWSTLRHWLSDVKDKNSVFSVLDEEIAKAKVVAEQMSRLTPERNLDLERYQEKGSQLQERWHRVIAQLEIRQSELESIQEVLGDYRACHGTLIKWIEETTAQQEMMK---------------------------------------------------------------------------------PGQAEDSRVLSEQLSQQTALFAEIE------------------------------------------------------------------------RNQTKLDQCQKFSQQYSTIVKDYELQLMTYKAFVESQQKSPGKRRRMLSSSDAITQEFMDLRT-------------------------------------RYTALVTLTTQHVKYISDALRRLEEEEKVVEEEKQEHVEKVKELLGWVSTLARNTQGKATSSETKES-------------------------------------------------------TDIEKAILEQQVLSEELTTKKEQVSEAIKTSQIFLA-KHGHKLSEKEKKQISEQLNALNKAYHDLCDG------------------------------------------------------SANQLQQLQSQLAH-------------------------------QTEQKECRAVAGVIDLGTVEIFPIFKAMQKGLLDQDTGLVLLES--------------------------------------------------QVIMSGLIAPETGENLSLEEGIARNLINPQMYQQLRELQDALALI-SRLTESRGPLSVVEAIEKRIISETVGLKILEAH----LATGGFSLSPSENCINLEEAFHQGLISAWLHSVLESYLRTSKNLIDPNTAEKIGLLDLMQRCIVHQESGFKLLPVKQLAGGMVSLKSGRKVSIFRAVQEGLIDRQVTVRLLEAQLFAGGIVDPRTGHRLTVEEA------VRHNLIDQDMACAILIRQLQTGGIIDTVTGQRLTIDEAVSNDLVAAKIALVILESLWSFMGLLWPESGEILPITDALEQGIVSTELAHKILS------------------------------------------NRQHIKALFLPATTEILSWKKAIESGILDRDLANNLKSICIPDVMPHMQLADSAEQNINPGAAVLPCSKSHPKATASQSE--------------------------------------------------------------NLLFQLMTHSYINVQNGQRLLLLDKELMETLTSRDEYQ-----------------------------------------------------------------------------------------------TSPPKVVEIGHQRQKTPEGLQESANVKISGTFSSGWTVRLPEFQFSSQNKEYPDREDCTTEKGKKTTVETED--------------------------------------------------------------------SSVENPEQDLFVEQKERN-PNIDALKVINKVKLEVQRQLIGTQREDQTAVSVRENASRGHLLTIPPAEAEGVPLVVDKDVFSVETPK-----KEHQPLRNTSFTCQNEQAHTLETEYIHDETGGSHIKPQSKKLQVQVKKTLGIKLELKSETDGNVHPLDKKEMLKKTFLAKDDHKESQEAQNIAGG--------------SMMMSEKTDEEDSGREIFLSCSHPLELLEEATLNVLSAQLLDGGIFHEQTGQKLLLNEAISRGIVP---SHTAVKLMEKLNMFQGFFDSQ---------TCESLTTEEVINEGLMDEKLLHNVLMADKAISG---------VLDPRTQTLCSVKDAVTVGLLDKETATRILERQVVTGGIIDLKRGKKVSVTLASTLGLVDVADQPELINL--------EKASKGRDAEKTVRERLISLQMETTGLIDPDSKAPLTVV-----------QSIDRGLLEREEAVRLLTKQVVDGGIIHHISGMRLSVDNAFRHGLIGEDLAEKLKRV----------------------------------------------------------------------------------------------------ENLNIHQIFNPETKENISLPKAIKLDLITSDLKREIQEVQAFTGNFVDLISGQRLTLAEAKKEGLLTNEAVLSPGMMHGIVDPENCRIVPYSELVKKCKIDIESGQRYLEVIPFSDI-----------------KDGVSDKVLTLSQAIQLGKVDFASTLKVLEAQANTGGIIDTATGKRLTLASALEEKLVDENMVRIIASHQVLNGGIVDIFSDQRVTLVEAIEKRLISPELANMIQIDSS-----------------------------------------------------------------------------EFSDHRAQIEKQEGIEVCALQNEFLGKDMLIACNQTAEMSCNKVEES---------ERLFQVENQSAQEKVKVRVSDGEQAKKSREISLKEF--------------------GCKDQRKPRMSSDAKEFISIINPHNLKGKSLGQVSLTHPYS----------------ECDFKLKEVARNNMGNDTNEEQEKAVTKIEIISHMKQS------------------------TSCLDSEEIRENQGEVILEVQETYCETSGKLPSEQVLQQPMNARVKSKREKREVIVEESIRTCKPAFLSEEKLYQETAIRDEHDSHIKSQPREM-------------------------------------TSSEKGKEADTEMGFSITFKIEESSSQVVPQGISVKHLDALTLFSSKQANEGKVNNLSLCLTLKPEENLSREIACGAQSEPFPCMTPRPEGLHYQESDGKAQVTGPSQISKTDKSFQGTTRQETN-YQDSWVTSK------------------TKETKHQISSSNECKEKSYQEVSFDPARGLKLEEITVSRPDSKEVRYLEFSDRKDLHHQGSKSDDKLCGTLKSEIATQELTGEKFLEMANPNVAGLEAGSIEDIVTQRGSRVLGSFLPEKLFKGVSQKENTGQQNAIIS----------PTVLETSEEKTVSLTVCSAVKTEKTPQEKLRESPGSEQTPFMTAPEGK-----------------------------------------GNGGVNPEPFRATQNVFTRQLCLEHDEKLVSYLSLLRNIEMRTKQIQPLEL--NLAELQDLLCQAKVLERELKDLTTLVSQELECVNQIIISQPQEVPAQLLKALEKDAKNLQKSLSSVSDTWNSRLLHFQNAVEIEKTKVLNQHTQLEGRLQDLRAWVGNKNLILNSKGSNSEIDVDSLNLCLQQYEDLKQPMAERKAQLDALAFDIQ------------FFISEHAQDLSPQQNRQMLRLLNELQRSFQDILEQTAAQVDALQGHLQQMEQEALVK-------------------TLQKQQNTCHQQLEDLCSWVGQAERALAGHQGRTTQQDLSALQKN-QSDLKDLQDDIQN----------RATSFATVVKDIEGFMEENQTKLSPRELTALREKLHQAKEQYEA-------------------------------------------------------------LQEETRVAQKELEEAVTSALQQETEKSKAAKELAENKKKIDALLDWVTSVGSS-GGQLLTNLPGMEQLSGASLEKGALDTTDGY--MGVNQAPEKLDKQCEMMKARHQELLSQQQNFILATQSAQAFLDQHGHNLTPEEQQMLQQKLGELKEQYSTSLAQSEAELKQVQTLQDELQKFLQDHKEFESWLERSEKELENMHKGGSSPETLPSLLKRQGSFSEDVISHKGDLRFVTISGQKVLDMENSFKEGK---------------EPSEIGNLVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEANVEKLLSDTVASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEG--EPAPDHRHVQETTDSILSHFQSLSYSLAERSSLLQKAIAQSQSVQESLESLLQSIGEVEQNLEG-KQVSSLSSGVIQEALATNMKLKQDIARQKSSLEATREMVTRFMETAD-STTAAVLQGKLAEVSQRFEQLCLQQQEKESSLKKLLPQAEMFEHLSGKLQQFMENKSRMLASGNQPDQDITHFFQQIQELNLEMEDQQENLDTLEHLVTELSSCGFALDLCQHQDRVQNLRKDFTELQKTVKEREKDASSCQEQLDEFRKLVRTFQKWLKETEGSIP-PTETSMSAKELEKQIEHLKSLLDDWASKGTLVEEINCKGTSLENLIMEITAPDSQGKTG-----------------------------SILPSVGSSVGSVNGYHTCKDLTEIQCDMSDVNLKYEKLGGVLHERQESLQAILNRMEEVHKEANSVLQWLESKEEVLKSMDAMSSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLVTYPNSQEAENWKKIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLSIDPNMLNAQKQQVQFMLKEFEARRQQHEQLNEAAQGILTGPGDVSLSTS----QVQKELQSINQKWVELTDKLNSRSSQIDQAIVKSTQYQELLQDLSEKVRAVGQRLSVQSAISTQPEAVKQQLEETSEIRSDLEQLDHEVKEAQTLCDELSVLIGEQYLKDELKKRLETVALPLQGLEDLAADRINRLQAALASTQQFQQMFDELRTWLDDKQSQQAK--NCPISAKLERLQSQLQENEEFQKSLNQHSGSYEVIVAEGESLLLSVPPGEEKRTLQNQLVELKNHWEELSKKTADRQSRLKDCMQKAQKYQWHVEDLVPWIEDCKAKMSELRV-TLDPVQLESSLLRSKAMLNEVEKRRSLLEILNSAADILINSSEADEDGIRDEKAGINQNMDAVTEELQAKTGSLEEMTQRLREFQESFKNIEKKVEGAKHQLEIFDALGSQACSNKNLEKLRAQQEVLQALEPQVDYLRNFTQGLVEDAPDGSDASQ-----LLHQAEVAQQEFLEVKQRVNSGCVMMENKLEGIGQFHCRVREMFSQLADLDDELDGMGAIGRDTDSLQSQIEDVRLFLNKIHVLKLDIEASEAECRHMLEEEG-TLDLLGLKRELEALNKQCGKLTERGKARQEQLELTLGRVEDFYRKLKGLNDATTAAEEAEALQWVVGTEVEIINQQLADFKMFQKEQVDPLQMKLQQVNGLGQGLIQSAGKDCDVQGLEHDMEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELIANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQLESLESRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGTQTAKIQQQIIRHK-------------------------------------------------------------------------------------------------------------ALNEEIVNRKKNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKTRYADITVTSSKALRTLEQARQLATKFQSTYEELTGWLREVEEELATSGGQSPTGEQIPQFQQRQKELKKEVMEHRLVLDTVNEVSRALLELVPWRAREGLDKLVSDANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRSEIFGTCGE-EQKTVLQEKTESLIQQYEAISLLNSERYARLERAQVLVNQFWETYEELSPWIEETRALIAQLPSPAIDHEQLRQQQEEMRQLRESIAEHKPHIDKLLKIGPQLKELNPEE-GEMVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRMPPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALLTTIKDTQDIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGETEKPEVRKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSAG-DDASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAREQLDTHMELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSG---SKTEQSVALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNTVLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEIS---NDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPEDSQKLDNFLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENSRDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDTEALQSLIDTHKEFMKKVEEKRVDVNSAVAMGEVILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQEPIPQNIDRVKALIAEHQTFMEEMTRKQPDVDRVTKTY-----KRKNIEPTHAPFIE-------KSRSGGRKSLSQPTP------------PPMPILSQSEAKNPRINQLSARWQQVWLLALERQRKLNDALDRLEEL----KEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAALHPNKDAYRPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYR------FGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDP--------------------------------CRARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASP-------------------------TRSSSSASQSNHSCTSMPSSPATPASGTKVIPSS----------------------------------GSKLKRPTPTFHSSRTSLAGDTSNSSSPASTGAKTNRADPKKSASRPG-------SRAGSRAGSRASSRRGSDASD-FDLLETQSACS------------------DTSESSAAGGQGNSRRGLNKPSKIPTMSKKTTTASPRTPGPKR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T8N6-1", "uniprot_id": "A0AB32T8N6_DANRE", "id": "A0AB32T8N6-1", "name": "", "aln": "MGSSLGCVKQPRDTGPGGGAPVSPKRKLRFRRKRKAKQKLKGSEVEDKRCRVLEEKDEGSVELTDESTARALDSTKLVSGQITTETETPTSVILVPGMAPIFGSTGTLRGSKMAILSPDPSPAWLGALRQFEVEGLSEESNTELEQGNTTPGGGRVCKVRERVQGVLERPCLLRSKRGDLEIEEDEHGPSELMFSVPSKTEKKGVVHIREFGGQLCVVRTVYPRDYGSPVWRDKVLEVHSEPPAASPVTEGIMKVQVSPAQGRPPGKNNSAKPETAAAQGKKVKEFLLDSSAHVVGGFSHPPQDLQSSGYASDVPLTSPETGGAVHTEWGSSSDVLDSSVLESPISPQETLTQPTTQISEIYVSGESGDLTAKEKLLIWSQQATEGYPGLRCTNFSSSWSDGRLFNALLHRYRPDLIDMQVVAQQSNRENLEQAFEIAESLG-VTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPKIPEGGEGIAAHEVDQRWTEYQSGFSSLLQWTRQHTTLMANRSFPHNPVELKALYNEYVHFKETEIPAKEREKSHIEHLYKLMEAWIEFG-RIKLPQGLHPNDLEEEWGKLILEMLEREKALRPAVERLELLLQMANKIQNTALDCEEKLTLAKNTLQADMSQLESGQPVRCENELGMYLQDCEALVRQLHLDLQVLRDEKYYQVEQLAFRVSCLQEELVSLRLQCASVYRKGHFSTGGLLGEHVGQRGSSGGLATLGAQTLLGAVAAAAS-LLRRPMSRADLVAMSSSEDEGSLRFIYELLGWVEETQDLLERAEWGSDLPSVEQHLQDHHIIHTAVEDLLNSLKEARTYESRVSPNLRSSYSETLSKLENQYCKLLEHSSWRLRCLESLRAFVSHCTEELIWLNEREEEELAFDWSDSNTNMAAKREQYADMRSELEEKQDVMRSLQDTADHLCLENHPAKQTVEAYSAALQTQWQWIKELCVCVEQHLKDNTAYFQFMSDSRDCESYLRQLQDTIKRQYTCDKNSRLGRLEDLLQDSMEEKEQLIEYRSTVASLVGRAKSVVQLRPRSADSNLGTTTPIRAICDYR-QIEITISKGEECVLEDNSQRTKWKVISPTGNEAMVPSVCFTVPPPNQEAIDTASRMEQMYQNVMSLWHQLHLNMKSVVSWHYLQKDIRNISSWSLDTMRLQPPAERQQALDNLDAHLTDFLSDSHESSLFTPTERRELEREAENCREHCQTLLVSLETVEKDELASRAYLSELQSIKSHLEDAESRLMRGIQTPHPSTLSGDA-ADSAVHIAEQEKLQQDLKGLQSDLGEVSRRCVSFFEEKPTSSSVPVLRSELNLAVEHVEKLNSLSSVYLQKLKTVDVLMKSLQAAESQVRKYESRLSEEDIVPADTAAIQALGEQLKQWHSELQEQDHIFQSLSLEVQQAREVGNQLSQLHPDRSPELDRYQEKAHQLTDRWSGVRRQMETRQADLEMLGSVLQQYREGHTSLIRWIEETTEKQENTQ---------------------------------------------------------------------------------PEQT-DSRALSEQLAQQTALVVEIE------------------------------------------------------------------------QNQVKLDECQTCSKQYSAAVKDYELQLMTFRAFVESTQKSPVKRRRMHSSSDVITQEFMDLRT-------------------------------------RYTALVTLTTQHVKYISDALRRLEEEEKEVEEERQARVGQVSDLLGWVKGLQERTG------------------------------------------------------------------RSAEPSLVAHQAISEQLAAKKEEVAEAIRSTQVFLMSKQASKLSPEERAQVVSQLDELTATYTQLCDS------------------------------------------------------SAAQVQHLEEQLAK-------------------------------EEKRKGQGVIAGVIDLGTMETFPVFQAAQHGLIDQDTCHVLLEA--------------------------------------------------QIVMGGLFQPDFPDKCSLDTGLSTGLINRPTFQSLEELSTAICLVNTTKFEQGHELPVAKAMKEGVIEELVGLRILELQ----ISTGGLKVGSSGETVSLDIARHKGLLPMDLSQKLQSCLQR-RELIDPNTAEKINLIDFQKRCVLNEETGLRFFPVKQKPGGTVCLCSGGKVGIFRAIQEGLIDRHVAVRLLESQLFAGGIADPRSGHRLTVNEA------VQLGLMDQDLACTLMTRQLTTGGIIDPVSGERVDLDEAIQRDLLSPRIALRVLESLQSFRAMLWPESGELLPVSEALQQGVVNRELALKALR------------------------------------------KRHSVGALYLPESGQVVPLHQAEK--ILEPQAVEFLKQTQVPDILPHATLSSSSYKKRLSLGSVSSSSPPASHAEISYDFSKGE------------------------------------------------EGISQEQDQNHLLTQVMKHSYIDCHSGERLVLLKPDFVELICENISSKNLAIPVEHKLKSISATVDNKSMSEIKEDLENEEPKIIQYNIACKDVCLEQTTEIPEEGLAPLIVTDRTFSEPLYKEFVQEKALSSKEFSEPKIKGKMPYKVVNIGETIEGTEDLTPLAETNKIITEPTKEMIRREKDLSSRDCVEPRIKKDVSDSKNIERSSTIEEAGEDCAYLTGTVRDLIKLSHEEVCQEKVLSLGQYKE-------LGITKDETASKKTEMCERPERQMEVFASLKDPEEVFIDPSHEVSSQEPIIATVMEASHEAWQRTVITSEECHEPTIIKGTNALSNTGMGDTIERAEETFMEPTGESWQMKVLSSGKWDESMIKKGQIPWTNTNVGDMLERVEEDHAPSTGSAKTSIEPLHKENLQEKVLSSEQYKEHISSKKTKMGETFEKQKEVVADLTHSEKLYVEPTHEVGWQENVLSVGKCEVPMIIQGKTAWENLGIDETIERAEEGLAPFTGTAKVLTEPLHKANLQGNVPSSRLLKELEIKKDETANKKTNEGETLEKQMEFAAGLTDSEEALICCTHEGVANLTGTEETCLDPSSEIGQRKVMSSGECDEP---------VIRKGKIALTNTNVGNTIERAEEDHALLTGTVRSLTEPLHKENEQEVLSSGQYNKLKIKKGETTSDKTKLGETLERQKEVVAALTGSEEALIEPILQVVLQEEVLPSKEYDEPMMIQGEDTRMNIGVGETIERAEEETTEDCALLTGTTIEPLHNVNLQEKVLPSEKYKESRIKEDETASKKTNIGEMPERQKDDVAALTGRELESMDEFVQQEKVLSSDECENSMIIMGKMAWVNTAVGETVERTEEDLAPIADTARALTEPLQEVNLQEKVLSTGKYKELKIKENEAASKILPPRSEEDLSRLSGTKETYMVTSHKLWEEQVLSSGECNDDAKTKKDKTDRKKLDMSRSCEQAKERLSSLTGTKSPFIEPLQEECWQKKEKKVSEASEQYEKSSIKTQKI-----------------ASKLTDLGKTIERTTEHLTPSAEMGQTSIVASNTSSTLPKTISDNKMLSEHHIADSTVNQSENKQIPKVEQAETSVVEITEQKQIDVDEG--SRLTSQDTVKIVQYDPLNSKLKEARTLKQ---------------------SVELDIFEHDANRDCFDKPDKEKKEDPLEFKTLSVELSADDVKFENMPMERQQGDLEIKGAGHMRKDGLETEIFPDSESKKQLVDTVIQESNDTSLEVLTEFTLKAEKRLQQAIKDIRPSKGKYVKSEQTRSTNQPQETSEIRWQEVEVGNSTTLPDCTTETNILRQTDTKSAISTASFSENNGDSKEQVLSTKETKA---------------KTRVKCQTVSEPAVSNVISSDIDEDLQNKEHMLKEKKTGGHGFEAEAEEMKDSKTDGFDVVSTTTMEVKVPGKKKGRGKNSKKAKMEKDERPLVSDTSVRIFPSEKAELDEQGGFTTSQEPFIKDGNETVQQSEMTQGSGTVSGSGENVQGQDMETGIDRTANEMKAPKWESDRENNTSQKEKTLTPHSPTIYKGKTDQNQEVTEVSKDLCTEVSEKKKKKKSKSKKAKQVVIVEEGEEKRDDETEKEQKMIIPEVQTQSSQSDQKEHVKKLEEAKQALAQKEILLRKAKESILKKVFERGVSEKQAAEELEAMRHSANNGERRITAQEGNS-----------VEMTSNKQTPSKKQDSKLHKSRQELSKNKDRSMPTTAEDLPGADIDACSSTKTQLLQDQRDKKTKSGLSEDDMNQDISSLKSSDDIVDIKQKYIVKIPNFIGETKERKAEEQNIEPLYSEDEKLIESVIELTSPSSSHEVAKSLPVEHVTDIPAIKDSKELLSSEACTPMVKIEPKKVKSSEIYSKRNEETLFKDEPFNQENNISGLPFKEVMPESDNTQKEVVEEYPMGSVERQPEVLQVNIEEMGRDATKVSKSSLARQECLEHDQQIVALLSMVRHIEVRLKQQQQQSVGRSLSTLDDIIRQTEALVLEIGDLEPEVHTEIESATQLLESNLEDVPPQLLMALEKDVHGLTRAYSAARDHAQNTLQGLRTQRDAQNEAVNSQLKSLQDHVDKLLSWVKETDTQMQEETGVDGQTVAEITRKQQLCEQLQNSLTARSNEVGNVAFNIQ------------VFISEHAQDLLPDQSRHLLGQLEQLQRVFHQAVGLNDARAEALLAQQMREHERLKKEQKVKEEKMEKERQATRDREVVQQQKAECSQKLESLTMWMAGAASLLASQRPGVESDDVHTLQEK-QRALKDVQKDIQT----------KSDLLIETIRSVEEFLSDQGDALSPEEKAKLQAALSQMKEQHSS-------------------------------------------------------------LTNSVHSSLAQVDTAIVTTQQQNTQRAKAEEQMQETQEKIDKLFSELSLLDDS-----------KRRSLGSIVTDNPLSVPQ----------ENALSSHSGMLQTELQQLQSQQAHLQQVAQSVRSLLEQPDSSVPPEEKQSLRAKLDQLQNQHQERLQNCQDRLRRADALTDEFTKFVQEHGNLGTWLDQSEKELCSLGEGEMDAMDLKNRVDEHKKLAEDVICHKADLRFVTISGQKVLDSVQCALQRMGSA----------DPALEETKNLVSDKLQDATQRYGSLHSKSSELGTRLSSLQERYQHYQDEAGSLDSWLNSQEQNQSIFKPSGEQTDPQALQRTLSTVQLLQDDLAERSVQLEKVKRAGKELVSIKE--SPTLKNADIKNVTDALEKRFETLSDSVSVRAEQLQTAVAQSVSVQEGLKALLAWLDGLPLSP----AAVQPTAQAVQDALTQNQKIRQELLSRQGSVDATLDSVSKLLKSAD-ASTASGLQRALQDLSQRYTAAQAKQSERETELRGLLPKLESFERQSADLRNFTQSRERALSPVGQPDCSVDDYRQTIEEVRSEITQESSQLKAFVELGSDLSHSGVLANVQSLLDTTKEVSEDFARLESNVNERFDSIQNCVQQLSDFRSRSGSLLRWLQTVQEQLP-AKEPNLSTEGLQRRAQQLKDLLTEWETQGNQVQELNKNSSQLENLIINTTAP--KNKTG-----------------------------VSQLNGASSPNSVNGIHTCKDLTEIQVAVADVNCKYEQLGSDLRERKSKQESSLELQQKARQSTEALIQWLGPREQSLAQG-QTASPSRPEVVRAQAQQTKVLLSELAEHSGKVEDLKNLLKQLIRDNPDSPEVDTWKRQLEDIDSRWTNANQTASQRQTELEACADRLGNFTTAASQLGPWLREKELMMSVLGPLSIDPNMLNTQKQQVQFMLREFETRQPQFDQLTRAAEGILSLTGDERSRDEQDLEEVRRELADISAQWDDLTSRLSGRSQQIDQAQGTSQHYLTLLRELSQSVADLGERLDAQASLSAQPEALRRRLQETGEIRSELEQRRGQLSQAEQLCTELSAIVAEPYLRDELHKRLESVSGPLKNLEERAADGLSQLQAALSSTQQFQQMFDELRSWLDGNTGNQTTGMSETLPCQPDALKTLLTQQEDFQRAIAQQRGSYELIQAEGASLLASLPAGDERLALQTRLNNLRQDWEVLNQHASEKHCRIKETLTRAELYQQHRNELVPWIAECEVKEAEINP-SLDAAVLDDSLQKARQLSLDLDRRRPLLESLNTAADQLLEQSCTGEEEVRDEKAQLNRRVDGLSERLQGRTAQLEELGSRLKEFEDGRQAVERRLEAARHQIEVQEALGPQACSNKSLERLRSQQELLNSVQPQVVYLRNLAQGLLQDAPQISAAGQDGGQKLLQQACDTEKEFEEVTEKTEQCCSSLESRLQGVGEVQSRVRDVFSRLADLDDELDSLSPVGRDADSLASQADAVRGFLSRLNALRSELENHGGECTTMLRREGSSPDLLALRRETEALSRQAGKLAERGQNRLALIESAEERVREFYARLADLQALLGRAEEVLNTQAVVGTEVEVIKQQLQEFKAVEREQVDSIQPKLQHVNAVGQGLIQSAAKHTDTQALEHDLETTNLHWNSLNKRVAERIAQLQEALLHCGKFQDALEPLLSWLSDTEELIANQKPPSAEYRVVKAQIQEQKLLQRLLDDRRGTVEMIRAEGERIAATAETQDRDKIQKQLQSLGERWTNLLEKASARQKQLEELQVLALQFHEAVEPLSEWLSATERRLSSAEPMGTQTSKITQQIVRHKALQEEVSSRENNVDRLESLSQSLHPLSCAADQDWLGERVGAVRSGHTELRDWCVRREAMLEQALANAQLFGEEEVEVLNWLAEVAQRLAEVSVQSYQPEHLEQQHKHTLALNEEIVSRKKTVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKSRYAEMTAGSSKALRTLEQALQLATRFASSHDDINQWLDRVEAELNN-----AEPDTTPAYQDRQKELKCVSAEKRLVLDTVNEVGSALLDLVPWRAREGLDRLVADANQRYRQADETITQRVQLVQAAIQRSQQYEEAVDAELTWVGETERKLASLGPLSLEPDVTVAQLQVQRAFNIDIIRHKDTVDQLLKTREDILESCSE-QQRDALKVKTDSLSARYEAVNQSHAERFSALEQAQVLVARFWETYEELEPWLGETETLITQLPPPAIDTEALRQQQDQMRLLRESIAEHKPHIDKLLKIGPQLAELSAQE-GATVRQRYNEAERRYMRIKEEVKSRATALDEAVSQS---VQFHDKMDPLLETLEGAVQRLRQPPPVAAEVEKIREQLAEHRATGLELDKLLPSFSALCARGEELISRAP--HDDPAAQAVRSRLLRLRSLWDEIRQRAEEREGKLQDVLDLAGKFWADMAALLSTLRDSQDIVKDLEDPGVDPSLIKQQIEAAEAIKAETDGLREELEIVRTLGADLIFACGETEKPEVKKTIDEMNGAWEGLNRTWRERMERLDEAMTASVQYQDALQGMFDYLDNAVIKLCDMPAVGTDLSTVKQQIEELKQYKVEVYQQQIDMEKLSHQGELLLRKVSDQTDRDMIQEPLTELRHLWDNLVDKITVRQHKLEGALLALGQFQHALSELQSWLSHTHATLDTQRPISSDPKAIEIELAKHHVLRNDVLSHRSTVETVNSAGSELLESSPG-DEINHLRDQLDELNRSWKNLLLKTDERQKLLEAALQQAEGFHGELEEFLQWLRRTESQLSAAKPTGGLPETAREQLQQHMELQAQLAQRGEHYHRLLDHGESILLARGGEDAGPGTTQTQQNLAMLQNKWASLNTKMEDRRGKLEEAVSLATGFQSSLQDTINWLTQAEQTLNMAQPPSLILDTVLFQIDEHKVFVNEVNTHREQVLALEKAGSQLRFASLKQDVVLIKNLLLSVQARWDKLVQRSLDRGRHLDEARKRAKQFHEAWRKLTDWLEEAESRLDSELEIS---NEPDKIKIQLAKHKEFQKSLGSKQPVYDTTVRSGKAMRDKATLPADTQKLDNLLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFAEALQALVDWLYRVEPQLAEDQPVHGDLDLVSNLMDCHKVFQKELGKRTSSVQALKRSARELMETGRDDTAWVKVQLQELSNRWDTVCALSVSKQTRLQQALKQAEEFRTAVQMLLEWLSEAEQTLRFRGVLPEEAETLQALLHTHRDFMQTVEEKRVDVNKAAGMGEAILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHEQRLETALTELLNNAALLEELLSWLQWAETTLVQRDTEPLTQDILQLKTLITEHQVFMEEMTRKQPDVDKVTKTY-----KRK---PAEHPSSL-------SDRKGARKHQQQQQQ------------HHS---VQVTGGNPRLTQLCSRWQQVWLLALDRQRKLNDALDRLEEL----KEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTSKLEMTAVADIFDRDCDGYIDYYEFVAALHPNKDAYRPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRVQHPGLKILRSDSSSSISSRIVTVTPGYFCCRARGRTNLELREKFILPEGATQGLAAFRSRGRRSKPSSRTASP-------------------------TRSSSSASHSAHSCASVPSAPATPTASSRSSQSQSRGYAKPWLAHSKTPTPTKCQSCPEHSQTPGHEGGSTTKLKRPTFHSSRGSLTGENGGTPTAAKPGRSETKRTP-SSTSGPA-------SRAGSRAGSRASSRRGSDASDTSELMETRSACS------------------DTSDT--------PRRPGAKPSKIPTISKKTP--SPKTPAGKK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9J3-1", "uniprot_id": "A1Z9J3_DROME", "id": "A1Z9J3-1", "name": "", "aln": "-------------------------MHSSSQSTLKRTQQLVRQTNGGRGDVLSSGSEVVHSSRGPAITTNIDDSNLRYRHETKRERTVEAVITDYPGVSPLGSVPHERTNFERTVTFQDPT----------GNSRRLSETGALVPAGAIPTSSTHYQQVTRNKR-----------------ISTEVLGSS--------------------------------------------VESTKTS-------------QRAPNGHRR--------------------VTTHIVRKVTTLSRAEENAQP-----AEDLLPPAKMIRSSELEYRRALPPAIESSSTQR-------------REISDIVVGKED-NVSAREALLRWARRSTARYPGVRVNDFTSSWRDGLAFSALVHRNRPDLLDWRKARNDRPRERLETAFHIVEKEYGVTRLLDPEDVDTNEPDEKSLITYISSLYDVFPEPP-SIHPLFDMESQRRVHEYRDLAQQFIYWCREKTAYLQERSFPPTLIEMKRLLSDLQRFRSDEVSARKREKSKLIQIYKELERYFETVGEVDVEAELRPDAIEKAWYRMNTALQDREVILQQEIERLERLQRLADKVQREIKHVDQKLTDLEGRIGEEGRRIERLHPVDAKS----IVEALETEIRHLEEPIQDMNQDCHVLNEGRYPHVSELHKKVNKLHQRWAQLRTNFHTNLVQKLSG------------------LKYPVHETTVTRQTRMVVESRQIDTNP-----HFRDLQEHIEWCQNKLKQLLAADYGSDLPSVKEELDRQQHEHKIIDQFHTKILNDERQQTKFSGDELALYQQRLNQLQKVYAELLSTSTKRLSDLDSLQHFLGQASAELQWLNEKEQVEITRDWADKQLDLPSVHRYYENLMSELEKREMHFATILDRGEALLNQQHPASKCIEAHLTALQQQWAWLLQLTLCLEVHLKHATEYHQFFGEIKDAEQWLAKRDEILNSKFSQS-DFGLDQGETLLRGMQDLREELNAFGETVATLQRRAQTVVPLNKRR--QPVNRQGPVQAICAYKQQGQLQIEKGETVTLLDNSGRVKWRVRTAKGQEGPIPGACLLLPPPDQEAIDAAERLKRLFDRSVALWQKKHLRLR----QNMIFATIRVVKGWDFDQFLAMGPEQRTAIRRALNDDADKLLSEGDP----NDPQLRRLRREMDEVNRLFDEFEKRARAEEESKQASRIFTEECLAIKSKLEDMARELDQIILAPLP-----RDLDSLEHVLEIHSDYERRLHLLEPELKHLQETFRTIALKTP------VLKKSLDNLMELWKELNTQSGLHKDRLKLLEASLAGLEDNEHVISELENELARHQDLPSTAEGLQQVFKQLNHMQDIITQQQPQMDKMNDAADQLGRMGVPTKVLG-----DLKRLHSNVERLNTRWSAVCNQLGERMRSCETAIGLMKNLQSSVQVEESWVDGTTERLSAMPTATSAYELDKLLGAAIERKPKIENVNVAGGRLIREAKIYDSKCLRFVDWLVEARPSFSPPRRDLRPADSDPGATQYYSQRLDNLNTKNDRLLEQLSQRLKTAIEVNGSDGLQYAESLQKPLKTFRVDFSAGSVPTGDGYAARQEDLYTTTYSTTQISSTKTTKSSTKSVYSSDGLDAASQEVSTAGLPQSQIQFNEIRTLKRSQQLGGHSVLDIAGIRDPRTGRVLTIGEAIQLRILDVRTGEMLVGDRRITLEQAADQGLIDLQLAKQLLEPGAGRDASGRELSLLEVIQREISEAESGYETAEKRIKVNNTVTVEQTSGELGSPENPRNIADAITAGSVDTKTGLYRVKSGQTISLAEAYERGYLIRHESVTIKSNALCLSDAIAHGLVDGAGWIADRNSGDKFRLDSAIANQLIDASVREVVDAKRDTKITLQEALQSGVLNAKTGRYVNEVTKEKLTFAEARNRQLIVKPYTLKDICDLNLLDKQAQITSPMRREKLSIMQAIEAGVLDGNLLKCITKRKGELVTLQEAIADGIVLPAECKYRDFMTGELISIPEAVERGLISSVAQRSIFDIDGFKDLRSNDYVSFNVALSRDLLRRKSTGFALETGRDSLVPLEVAVSEGLVRQEVYEMFSRGIGVQNASGKELSVFDLVYHNLIDPKTGYLLDPKTGETVPLDTAIERKFITPEGALLLSSLLNITLTTETVTRTINRYVTIRAGSQEPVDSVLLTFTEAVRQGFIDEERQLFKDPKTGNIYSVQQALNYGLLVPDSNQTVPEPTNRKKTKSTITIVTKQIIPEAEPIKLNTQHTKYVEKSVEIPISQELVKPHRVVSEFINLEKSSYIEQNVTERQIMELPPGGWRLKDAIEQRLFNPDTGVFHVQGTDRLVNFEECINKQIINNLSLSVIDPNTGDKISVQSAFERDILDSYGNYTNSRKQVQGMRSAIDESKIILETVPATRGANQKTILRITKVNNIPDVLEVSTPLKDAPPKFVEVLTCQRELASPEPLQIAPGAIYDPSTALVIFTQTGETENIFDAARQGLVDEQLIKIVDPTTKQPISVTEAIARSIYDPKTATILDSEGQPVDLITATKLGLLSVVGAPLVAAEGALRTVRFVTDPRTGEQIPVEVAYERGIVSRDQLHRGRSFDSEPATVEDKVVVLQRMRKVILKPKDALRKGIIDEETCEILENTSNFTNPKGEVVNITEALNTGLIDGRRGQVIDPQNNRVLN--LRQAVEQKIIDSEQTNHILMPLAKSLSVPRLADQGLIDPQTQTIVHPESGYPLSIHEAIVCEVLDPHSKLHKPEKCTLEEAITKGIINADDSTFNYKNKTLNITEAIEAKLFDPSYDQQKSKVEIPPVGMIFPVAVEKSLVEPSKRVVLHPSTKKALPIKQAIEENFIMSIPYSPKPDAIEVVTAMEQDLIDVAAQTLTVPSTGERIPLRQAMENGVLVVKNLSDFVITQKPIPKTEIMETVRAVHTVTTKTIELMQGYVLISNNEVQNVNTGEVCSLEEAKELGILREESTTRETKAAAGESPESVGDVGTSGDQTVIVEERTQTVVVSSDTRKQEMQVVSTTQSTKDTSVPSVSEIETKGSKEPSKTLQNVKDAAKLGALGVIAAPVLAGGAIVSGVKSLIKSVKSPTEDAKSTEKPKEPQTSFIEQERRKELQPQQVPSEVDNLLSETENFISSTTANFIANEKQQDKPDTLPQESNLPLEVESTSTLTTTTVTTITTSSTTTETGNLEPVVVEDVSTTVKEDKVVVKPSTVPEDKTEVSKITETITTVTSNETDTVPEKISQKSASEESAKKDPVVTKDTSSRPAETETSPKPVQKEPTPDPAQNTEFPESIKKDPTPEPDYKETATEAAQITPKEASPAPTNKNEQSAEPTSKPEPMPRTAKKEEISEIEPPFTAPLAPFVDQLAETKITEIKTEFKEPVTSSQTITTITTTVKTVDEHPIVEEVDEVSKSEKIVDVEEPTVHQQEPIKVNETSDDSTRTEPTNEIVHEERVVTVEEPTITETTVTTTTITTTTTSSSEETLPQENTATVKETPLNEPVPSSPAETKEIEQTTNDDQKKPEEIVDTEKKTTEQKPVETIPTEPISTSETTTVTLTTKTTIVDEGKLHPPSDIEQIIQPHSTSDKHQSLVDFIEQEKGTQPAEGGSNILQNVKDAAKLGALAIVGAPVLAGKALVDALTTEKTLKPEHSTSQVVTETVEELPTEIITTSTATLVTKVTTTTTTTTTSTSEGTPDDEALDVVKLPAELVESSVKREVPRTLAIGDAISQKLISPDECQVIVDGEQQSQTVSTLLKEEQLSPLDEVQIIDDKLIVLQQVSYLVDADTELTPQNLYELNIYDPENQYFIDPSTGQKISFHTLVFDMNVFNPETILVKNFSTGKYETLTAALERPLLDRHTGHMVDPKTGKKIPFFECVDRQWIIRANPEEQKPSGIENVTIDTQTGQVVLDDGRVCSIVEAINSGKLDIQSISVRDPVSGEVIPLRMAIELGVVDMQAGTVIDIQTLKEIPMELAFQLGFLVPGARKPISLEAAVRKGLYDPETGKLFDSESQNQVDVQKSIEIGLVDPKISLIVDTVTKKEVKLDCAIEDDLVLPATGQIKDNKNNTLVPFDVGVQQCLLKTDNVTWSLPELLQREYYTPSTGKVLNPVTGEEILLQQAIEMGFVELETTLVKDVDHDKILPGKEAAKVGLLDTVRGTLSSPNISLDEAFVKGYLISTKKPLSLVDCLLRGLYDPSTAKFTIDDKQLDLKAAIAQKLINPEELVLLDPKTESIISITEAIAKGYLDPIEGYVINPYASTKLSLHEALENRILIPPKRKRSLPDAVYRGLYDPKTGQFSNTVTREKLTTERAIRRGILDPDSTVVNVGSGQIIPFGVATETGIVDSKHGTVRDADDHPIDFKEAFDRGILVEAKKPLRLIEAVVKNVYDEVDGHFVDPKSGEKLNFAEALNTNLLDEHSVQIRDFKTGLYKQLNLTHAKDTGIIDAQNSKLLYNNQTMTLKHAFDIGILMDVNAPISIQRAIHQGLFDDKTGKLSDPRTGRQITLLESMRSFVVNPHLPCYFDEQTEQMYTLSETCRNGIINRREGVFREPGSNSFVPLGEALSLG---LIVDIENAGFGLYELLSMGFYETSTRKVLHPVTNRKLNLNEACVEDVVSLSSSLVKHHETGKYLRLANAIKEQLVDDSRGCYNLGNEQLDLQAARARGLIVSNRRLLSLELVLRQQLYRPETGKFCDPTTGEYLDLIEAIHSGFIDPATTVFKNQLTGKELPLTEAIENGDIDVSKGRVFDPKSKSAYNYDVALSRGILVTITRPLTDRNDVVRRQDSVELLNQTPVSVVISKPREMSLEEAIRYNIIDPKTALVRDFDSFKFLPYSVAVERGLVDTTKRTLVDPKALYFAFDPTLIVYVREPVTFDQAAESKCLDLQTGLLTYVPASVPGSATAAPASDDSANDSLTVIETPKVYTLKEAASAGVVDPDSALVKDLAKAKLVRLPEAFRKGLMDANKANVLNTQTSKLCTLQEAYESGLICTPKRSFGLLEAITFNLYNPTNGCLVDPFQMHPDIIRRRKFTLAEAIGSGLVDPSSTVVRDPSTGVIVPLTAAISSGLIDATEGRLTDANEPKNNIDLVKAAEKGLLLPAEQRQAVFEKFNMCEENVNDLLKWVTTVEQKISSVGGPREKIDELRNQINALKQIKDEIESQQRPVATCLEQIRQIVLTGGDVLSAPEVTTLENSGRELRSRVDRVNDRTVRLLRRLEAGRDELTKLRSELDVFSDWLQVARRTLEDKERSLSDLTRLPSQADSVREFVSDVIGHQADLRFITMAAQKFVDESKEFLAILNDFRTSLPERLPHVEPLSSAESPIRQEVSLVSAQYKDLLNRVNALQDRVSGLGGRQREYQDALDKANEWLRSVHPRVSRIISEPIAGDPKGVQDQMNEAKALHNELLSSGRLVDNAQQALDNLLRSLGGQLSPMEINQLELPIADLKNNYQQLLDNLGEHCKTLDKTLVQSQGVQDALDSLVGWVNQAEDKFKMNLRPASLIKERLQEQIREHKVLLADLQSHQASIDSVQVSAKHLLASASNARIAKKVESNLNDVTVKFEKLYEKANKRGEFLDDVYNRLSRYLDEISTVEQRMASLQEALDSRETSLLSTEELARRMNELSRDKDQLAPQFEDCVRSGKDLISLRDVTDTGVLRDRIKALESQWRNINISIDERAKLSKQKAEQQLAYEGLKDQVLSWLASTEARVNGLPPVAIDLDRIKQQHDELKPICKDYRDYAPTIDKINDIGAQYDALIRPESPARKRSTYSPIKRTSPLRRMSGDARSPSPTKGGILSPLSTGSSGFGSRRSSQDGFQLSELSPVQQQLSEINNRYGLIGVRLNDRQHELDNLNEELRKQYENLKGLAQFLERIQRQLPKE----SVSNKDEAERCIKQARKILEDMYEKQSLLDTTKAQVKDILRRKSDVPGAEQLRQENDSIQEKWKNLNDICKNR----IAFSEKLRDFLDTHGNLKSWLDSKERMLTVLGPISSDPRMVQSQVQQVQVLREEFRTQQPQLKHFQELGHDVVDHLAGTPDAQA-----VEIKLKDILGKWDDLVGKLDDRANSLGGAADSSKEFDAAVNRLREALQNISDNLDTLPTDGDHQENLR----KIENLERQLEGQRPLLADVEQSAATLCNILGDPASRADVNSRVAALEKQYLALQKKLDTKKAETEASLRDGRHFAENCSKTLGWLGGELSNLTD--RLLVSAHKPTLQHQIDTHEPIYREVMAREHEVIMLINKGK----DLTDRQQDRGVKRDLDRIQQQWEKLRREAVDRHTRLQTCMEHCKKYSQTSETFLAWLRTAEDKLADLTPGVLSKAKLETRLRDLQTFRSEVWKHSGEFENTKGLGETFLSSCDIDKEPIKAELQDIRDRWERLNNDLIARAHEIENCSRRLDDFNDELRNLDHSLGRCEDRLAAHDALGGAAKDPKLLERVKAIREELTNLSKPLQSLKALAKDISAEARAAGGDAD----HLTSEVDGLADRMSELQGRLDDRCGELQSAATAVSQFNEQMKSLGIDLNDLETEIEKLSPPGREIKIVQVQIDDVGKIQTKLDRLVGRLED-AERAADVLVDAGFAADTTQTREQISTLRKTLGRLDNRVRDHEDNLHSTLKALREFYDHQSQTLDDIQDVSDEFKRMKPVGSELDQIRRQQEDFRNFRERKVEPLAINVDKVNVAGRDLVRSAGSGVSTTAIEKDLEKLNDRWNDLKERMNERDRRLDVALLQSGKFQEALAGLSKWLSDTEEMVANQKPPSSDYKVVKAQLQEQKFLKKMLLDRQNSMGSLANLGKEVANHCEPGERASIEKQLNDLMKRFDALTDGAEQRELDLEEAMEVAKRFHDKISPLELWLDNTERSVKAMELIPTDEEKIQQRIREHDRLHDEILGKKPDFSDLADVTAQLMHLVSDEEAVNLGEKVRGVTERYTGLVDASDNIGALLAESRQGLRHLVLSYQDLVAWMESMEAELKRFKSVPVYAEKLLEQMDHLLELNENIAGHASNVESTVESGAELMKHISNDEAIQLKDKLDSLQRRYGDLTNRGGDLLKSAQNALPLVQQFHEAHNRLVEWMQSAEAALAP----------SEPRQADVLRLEGELADMRPILDSINQVGPQLCQLSPGEGAATIESIVTRDNRRFDSIVEQIQRKAERLHLSNQRAKEVTGDIDELLEWFREMDTTLREADLPAMEPKLVRAQLQEHRSINDDISSQKGRVRDVTAASKKVLRESPQSENTATLREKLDDLKEIVDTVAQLCSERLGILEQALPLSEHFADSHQGLTAWLDDMEQQISRLSMPALRPDQITLQQDKNERLLQSIAEHKPLLDKLNKTGEALGALVADDDGAKINEILDTDNARYAALRLELRERQQALESALQES---SQFSDKLEGMLRALANTVDQVNQLDPLSALPQKIREQIEDNDALMDDLDKRQDAFSAVQRAANDVIAKAG-NKADPAVRDIKAKLEKLNNLWNDVQNATKKRGSSLDDILSVAEPFWKQLNSVMKTLKDLEETLSCQEPPAAQPQDIKKQQVALQEIRHEIDQTKPEVEQVRRHGSNLMNMCGEPDKPEVKKHIEDLDNAWDNITALYAKREENLIDAMEKAMEFHETLQNLLKFLTKAEDKFAHLGAVGSDIDAVKRQIEQLKSFKDEVDPHMVEVEALNRQAVELTERTSPE-QAASIREPLSVVNRRWEALLRGMVERQKQLEHALLHLGQFQHALNELLVWINKTDSTLDQLKPIPGDPQLLEVELAKLKVLANDIQAHQNSVDTLNDAGRQLIETEKGSVEASTTQEKLRKLNNEWKQLLQKASDRQHELEEALREAHGYIAEVQDILGWLGDVDAVIGASKPVGGLPETATEQLERFMEVYNELDENRPKVETIQAQGQEYIKRQNQMKVS--SSNLQHTLRTLKQRWDAVVSRASDKKIKLEIALKEATEFHDTLQAFVEWLTQAEKLLSNAEPVSRVLETIQAQMEEHKVLQKDVSTHREAMLLLDKKGTHLKYFSQKQDVILIKNLLVSVQHRWERVVSKAAERTRALDHGYKEAREFNDAWSGMMQYLQETEQVLDQIIEEATASKEPQKIKKYIGKLKETHRQLGAKQSVYDGTMRTGKNLLERAPK-GDRPVLDKMLIELKEQWTRVWSKSIDRQRKLEEALLLSGQFSDALGELLDWLKKAKSRLNENGPVHGDLETVQGLCEHHKHIEQDLQKRAAQMQGVLKTGRDLERSG--NNPEVGRQLDEMQSIWEEVKSAVAKRGERLQVALVDAEKLNARVQALFDWLDHAEHKLRYAKNAPDDEKVSREMMDIHMDFMKDLRVREREKTETFEYAEDIINKAYPDAIPIIKNWLSIIQQRWEEVRQWAINRESKLEQHLQSLKDLDDTIEELLAWLSGLEGTLLNLKHEQLPDEIPPVEKLIEDHKEFMENTARRQNEVDRACKPRQLPPGARKPSRSGKTPVFKGSRDQGLNARKGSRITPTRDTPDRDRLPHYGPRFSPSTSGPELEFRSPRAKLLWTKWRDVWMLSWERQRLLNDHLLYLKDV----ERARNFSWDDWRKRFLKYMNHKKSRLTDLFRKMDKDNNGMIPRDVFIDGILNTKFDTSGLEMKAVADLFDRNGEGLIDWQEFIAALRPDWQERKPANDSDKIHDEVKRLVMLCTCRQKFRVFQVGEGKYR------FGDSQKLRLVRILRSTVMVRVGGGWVALDEFLQKNDP--------------------------------CRAKGRTNIELREQFILADGVSQSMAAFTPRRSTPNAAATASSSPHAHNGGSSNLPPYMSGQGPIIKVRERSVRSIPMSRPSRSSLSASTPDSLSDNEGSHGGPSGRYTPRKVTYTSTRTGLTPGGSRAGSKPNSRPLSRQGSKPPSRHGSTLSLDSTDDHTPSRIPQRKPSTGSTASGTTPRPARLSVTTTTTPGSRLNGTSTITRKTASGSASPAPTSNGGMSRSSSIPALTGFGFKPIRRNISGSSTPSGMQTPRKSSAEPTFSSTMRRTSRGTTPTEKREPFRL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: . : . * : . . . * *: : :: .* . . : :* .. . : : . : .. : : . : * .. . * : .. .. . . . : : . :**:* :. *. :::*:* ** *::: * *.*:: .:*:*.* ** *.**:** ****:* . . : **.** **.:.* ******.****. .*****:***:**:**.**: * . . : * : * **:. ..:: * :::* : :::** . :*:* * .: :*:. *: *::***.:: .:** :* ::* .:.: :*: :*: * :: : :** *: :**** * ::*:*:*. . ::*** :. : : ::* :** .:. :: * :*:*. :* :.:: : * :* *:.:: .*: . :.: : * . : * .. :: : : .: : .. :* : * : * :: * *::*.*****: . : :: *. :::: ..: : . : :.* : : * : *.:*:. *.:* . *: *: *:**: *:.:.: ** *** :*: *:: **:*.: ::.: : : :: *** :: : :: * .: * ::***.: :**: :*:* * *: :* :*:* *:*. : *.**:.: :: *.:* : :: :: ::: . . *.: * **:. : :*:* .:**:* *::::* *. * : .::*:* *: * :: * *.: .* *** *.**:* :..*:*. :*..*: :***: :**: *.*::: ::. ::**:: *:. : : : : :. *.:: : * : *: . .:*.:. . .: .:..* : . : : . ::.: :: : .* *: **: .: : * : . . : :.. :. *: *..:* :. : :.* .*:..*: :* ..: * : ::** ::. : .:: * : * .*:..: : : .:: *.: . : ::: :. :. : :. :*.* :.: :* ** * *: * . * :: : : *:: ** : . .. * ***:*: *:: ::.. . *:. . . * : ::.:: : *: : .:.* .::*:** ::* : **:* * ** :: :. * :.. ** . . : . : : : : :. .:* :* : ::: * : : : .:: . :: : : :: *:. :*. . :: * : * . .* :: : . * : :: . : :: * * . ... * :* :. : : : *: : : *: : : :.. .: . : : . . : * : :: ::: *** . :. : :: . :.. * *. . :*:.: . *:: :: **: *: .: : **: :.. * . . . * . . .: .*** *:.****:*::.**.:: : . . : :::. .: :* * .: * ::. * : :.:*. .. : *: : . : .. ** :* : .: *:::* . ::: ::. ::: .. . :. : ..:: * .: :. *:.::.** .**:.:.:*: : . :*: : : : :: ::.*:::. ..::: :*. . * :: * ::: :: : .:: * : : . : :.: .. * . . . . : ::*: : :: . . * : : : : .:: .:: .:.** . . :* :. . ** .: : :. . :::: :.** : :: . : ::* .: : ** :.. : . . .* * :. . .:*: :* : ::* :* : *.:*: . : . .: :. ..: *:* :. * * :. : .. :. : :* :: ::. :: * : :: .: .: :: :.::.:* . .: * :.:* * : .:* .** .** *: ****:* **.*: ****.: .**.::: * .:: . ...:: .. *. .* .* :* :*..:*..*: .:. * .* .: :. * : : :.:.*. .: . : : :: : ::. :* : :.: . *. ::.: : :::.*: :: *:. . :*:* . ::* : .: **. : .: : :..: *: : :* : : : : . :: :* .:. :: :: * .::..** * :.: ::: *:: : :.: *. : ::.*: .: * ::: *. . *: * : : : :: :* : .: ::... .:: :: * :. . : :.: * .:: .:*: ** :*:: : ::: : ...:: :*** * . * **:::: :* * :. : *: :::.: :* . . * :. ..: *: : .. * ::. .:.:.: :::.: * **: *:: :.. **: . : * : : : .::. * :* .. :* * : * :.: .:* : *:* :* : : :. : :.:** : ..: **:*:: *.:* :*: ... :*:.: ::::** *:.*::**.. .. .:*:*:: * :** *:::: :* :*: ***:.****:** * .**:****::*******::*:*****:****:*:::* **: :: : * .:* .* :* .* **:.* *: * . * *: :**: :* :**: .*:. :*. * . : * : *: ** *:* .*. ***:* .: ..*:.:::.* *:*: :.:*.: :::***.:: **.::* ... *:: ::* *. :* .::: : *: .* * * .*: : * :**::*:*. * :* * .. :: :*: *.:: : : ::.: :. : **::: * * *. * . .* . :* . . **** ::::. ** :*. : :: .:: . : :: .*: * : * ::: :** . **:* * :* :::: * .* : *::*. **: : : **:: . * :******* :**: * * * * .:: * :.: : : * :: *::.* **:.*:.:* :* **:: :*.:* . .::. :.* :**** : :: : :*:* :*.*: .:::*.:: . * *.: :: :* :: :*:::: :::* .: *:*.:* ** :: :::.*::* :: : * *. :*. **:* * : *: * * : *:* :* *::*: ***.:****:* *::::.**:.:. : :* *.* :** :::::::** ::.:* :: ::. : .**:*:.:** *::::*.:* ** : :::* *.:*. : .:.: : : *:***: :.: *: * :. **::** *** ********.** *:.:*. ** :**..**: :*:**** :** **: :*: :* *:*.** :*:*:. * : . :.:* :*. *:.:* *:.:*:: *: :*::*.*: .*::::* * : :.*:**.******* ***: .**: :* . . : :*. : :. . :: ::.: *:::* : :: .::: *** *:. ** *:.:** ::*** **: *. *.* * :*:*: *::****: ::*. **: :: *:: *.:*:: * ****:******:*** **:::*.:: :* * **.. *.*::*::** : ::*:::*. **. :* : ::*:*** :.* ** :: **.**.*** *:*:*: : ::: * **::* *::::* * .**::**:*******:**** :** *:*** :.:.:* *: ******: * .* : ** ::::* **:. :* : ::.*:* . . :.. * **:*:.. *: * ..: **: ** :** :. *: *::**..**:.**: *:: :. : ::. * :**: :. :. : . : .* *: .:**.*. **:*::**: *:*** ** :::.:** * .* :****:*:. * **:: . * :.::* :: ** :*: ***: :*:* :**:. *. ** . . * . *.*.* : : .** . * ::*::**:*: :*** *** * *::: :. **.:* ***:::::*******: *:**::***::* *.*: ****** :** *: ***.****:***: :* **: **:***:*: : :*:.*:***.***.* * *.* ::*:* *:**.*** *****:*******************:****** **** ***:****:****:***.:*.:*.::.* .* .:.:: ::*. ** * . * * :*:.::.. . :... . * *: *.* ** . . :.: . . ::. *. : .*** .. :: * : :.. :... * : * : .*: :*: .*: :.: :* ", "identical_positions": 1151, "similar_positions": 1929, "identity": "12.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3625", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y4W2-1", "uniprot_id": "LAS1L_HUMAN", "id": "Q9Y4W2-1", "name": "Ribosomal biogenesis protein LAS1L", "aln": "MSWESGAGPGLGSQGMDLVWSAWYGKCVKGKGSLPLSAHGIVVAWLSRAEWDQVTVYLFCDDHKLQRYALNRITVWRSRSGNELPLAVASTADLIRCKLLDVTGGLGTDELRLLYGMALVRFVNLISERKTKFAKVPLKCLAQEVNIPDWIVDLRHELTHKKMPHINDCRRGCYFVLDWLQKTYWCRQLENSLRETWELEEFREGIEEEDQEEDKNIVVDDITEQKPEPQDDGKSTESDVKADGDSKGSEEVDSHCKKALSHKELYERARELLVSYEEEQFTVLEKFRYLPKAIKAWNNPSPRVECVLAELKGVTCENREAVLDAFLDDGFLVPTFEQLAALQIEYEDGQTEVQRGEGTDPKSHKNVDLNDVLVPKPFSQFWQPLLRGLHSQNFTQALLERMLSELPALGISGIRPTYILRWTVELIVANTKTGRNARRFSAGQWEARRGWRLFNCSASLDWPRMVESCLGSPCWASPQLLRIIFKAMGQGLPDEEQEKLLRICSIYTQSGENSLVQ--EGSEASPIGKSPYTLDSLYWSVKPASSSFGSEAKAQQQEEQGSVNDVK--------EEEKEEKEVLPDQVEEEEENDDQEEE----------------------------------------------EEDEDD--EDDEEEDRMEVGPFSTGQESPTAENARLLAQKRGALQGSAWQVSSEDVRWDTFPLGRMPGQTEDPAELMLENYDTMYLLDQPVLEQRLEPSTCKTDTLGLSCGVGSGNCSNSSSS-NFEGLLWSQGQLHGLKTGLQLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BE28-1", "uniprot_id": "LAS1L_MOUSE", "id": "A2BE28-1", "name": "Ribosomal biogenesis protein LAS1L", "aln": "---------------MDRVWRAWDGQSFKENQPESPSARGIVVSWLSRAEWEQVTVYLFCDDHKLQQYALNRITVWRSRLGNELPLAVASTADLVRCKLIDAAGTLGTDELRLLYGMALVRFVNLISERKTKCSNLPLKYLAQEVNIPDWIVELRHNLTHKKMPHINECRRGCYFVLNWLQKTYWSRQLEGSLKETWELDEDQLDAEDPE-EEEREIIADDVLEEIPEPQDDDKDEELAVEDDANTKGNEEVASHPEPSSRHKELYEKARELLVSYEEEQFKVLEKHRHLLQAIKVWNNLSPRVQCILEELKSISWENRDAVLDAFLDDGFLIPTFEQLAALQIEYEDGQTEVQKGEVTEPNSHKNIDLNEVLVPKPFSQFWQPLLRGLHSQTFTQALLERMFSELSTVGSTGIRPTYILRWTVELIVANTKTGRNARRFSASQWEARKSWRLFNCSATLDWPQVIESCLGSPCWASPQLLQVVFKAMGQVLPDEEQEKLLRVCSIYTQNGENGLAKAIEGSSSSSTGKAPYTLDTLHEDLQPPGTNCESEESIQQKE-QGNLKDVKQEEKKENEEEEKEEEEMEEEEEEEEEEKEEEEEEQEQEEHQEEEQEEEEEEENQKVFQDQMEADVEESDDVEEEEEVDDEEEDEDDDYDDDEEEDRMEVGAFSLAQGSSVFENTRTTSRKREALQGSAWQVSSEDVRWGTFPLGRLPGQTEDPAELMLDNYDTMYLLDQPVIEHRLEPQKSKSSTLSLCCGGSNTNSSSSSSSGNMEGLLWNQGQMHGLKAGLQLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2CF03-1", "uniprot_id": "A2CF03_DANRE", "id": "A2CF03-1", "name": "", "aln": "------------------------------MKKETVGKTRHVVPWMNKAEYEHVLEYLYSKEPALQKHALHRISAWKGRFGQSTPVAVESTADLVRCQVLDSTGQLEANDLVLLYGMALVRFVNLITERQQKKVAKPLRRLARKINIPEWVVNLRHDLTHRRLPSLKWCRKGCGFVLDWLHQEYWSRQMGNQLTEDWNS-----------------------------SSDDEGEDDVVKRHEGDLLSRQ----------REIEAHKKIRELLISYEREQFQTYEELAKHGGQGGAWPDASADLSWILTQIKHFATESRDVLVDVLLQDGFLIPTTEQLESLDVDP----------------SEDSVDVFSPSLPRVFFHFWLPLLRVLNSSGFINMILDKLFSELSNEPST-PRMYYIASWISEIILCNSKTETKAHRK---QKVSKE--RIFVNRLHFRWHSLISACVNAPCPATPFLLRQILNDMDKPLPPDAQKNLLQLCSIYTQG-----YHCDPSAGPSDPAEPVYTLQNLQERLKSNTS--------QNRDVHSANHTAK-------------TTQIPPTEELQEKLSTETVQE-------------------------------------------------------------------------------------RNSALQGSAWTVCTDKVPWKHYPLGKVPGQPEDPSCLVVESFSTFTVFDQQVELDQLPQQHGNRSVPIQSRGASGS-----------DGLLWTHSDMSKLKAGLTLF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . **.*:.:**:::* **:..: **::**:**:.*:.* *:. *:** *****:**:::* :* * :::* **************:**: * **: **:::***:*:*:***:***:::* :: **:** ***:**:: **.**: ..* * *: ..** . : . :.: . : . * ::: ****:***.*** . *: .* : *. :. :* ::* .: *.*:.::*.:*:****:** *** :*::: *...:*: . :*: * :** **** *:*. * : :*::::***. : * ** * *:*:.*:** :*:* * ::. *:* : * ::.:*:.:** *:* **: ::: *.: ** : *::**::******. : .: .* .:. ***:.* ::. : *::: :. : .* :: : :*: . : :* :. ******* *.::.* * :***::***.***: *:::.:.*: ::** * .:* . : .. . * .. :****.:.:: **:** **", "identical_positions": 208, "similar_positions": 210, "identity": "26.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3627", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0KXQ6-1", "uniprot_id": "A0ABK0KXQ6_RAT", "id": "A0ABK0KXQ6-1", "name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase", "aln": "------------------------------------------------------------------------------------------------------------------------------------MGPSVLPAWLQPRYRKSAYLFIYYLIQFCGHSWILTNMTVRFFSFGKDSMVDTFYAIGLVMRVCQSISLLELLHIYIGIESNQLFPKFLQLTERIIILFGVITSQEEVQEKYVVCVLFIFWNLLDMVRYTYSMLSVIGTSYAVLTWLSQTLWMPIYPLCVLAEAFTIYQSLPYF-ELFGKNST--MLPFDISTYFPYVLKLYLMMLFIAIFIRKEKTSSEDLLSNRRKCETACCTGDKMG----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AKM2-1", "uniprot_id": "HACD4_MOUSE", "id": "A2AKM2-1", "name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4", "aln": "------------------------------------------------------------------------------------------------------------------------------------MGPSVLPAWLQPRYRKNVYLFIYYLIQFCGHSWILANMTVRFFSFGKDSMADTFYAIGLVMRVCQSISLLELLHIYIGIESNQLFPRFLQLTERVIILFGVITSQEEVQEKCVVCVLFILWNLLDMVRYTYSMLSVIGTSYAALTWLSQTLWMPIYPLCVLAEAFTIYQSLPYF-ESFGTNST--VLPFDLSTCFPYVLKLYLMMLFIGMYFTYS-----HLYTERKDFLRVFSVKQKNV----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VWC8-1", "uniprot_id": "HACD4_HUMAN", "id": "Q5VWC8-1", "name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4", "aln": "------------------------------------------------------------------------------------------------------------------------------------MGPLALPAWLQPRYRKNAYLFIYYLIQFCGHSWIFTNMTVRFFSFGKDSMVDTFYAIGLVMRLCQSVSLLELLHIYVGIESNHLLPRFLQLTERIIILFVVITSQEEVQEKYVVCVLFVFWNLLDMVRYTYSMLSVIGISYAVLTWLSQTLWMPIYPLCVLAEAFAIYQSLPYF-ESFGTYST--KLPFDLSIYFPYVLKIYLMMLFIGMYFTYS-----HLYSERRDILGIFPIKKKKM----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NVN2-1", "uniprot_id": "A0A8M1NVN2_DANRE", "id": "A0A8M1NVN2-1", "name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase", "aln": "------------------------------------------------------------------------------------------------------------------------------------MGFSLG----------FIYLFSYNLLQFCGHTWIFANMTARFLSFGKDAQFGTFYFVAVMMGACQLLSLLELFHIADGFDECRLFPRFMQVIERNVLLFLLIS-LEEFQSKPIVCVQFYLWNILGLLRYPHRLFCLIGTPYFKMLWVHQTLTIPVYLMSAVTEGISIFLMLPYLSESEGTDSVQPKVPAPMYMYSPYIVMSWILLLVLGSSLTVL-----LLLKERKENLESWNKKLN------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJX8-1", "uniprot_id": "Q9VJX8_DROME", "id": "Q9VJX8-1", "name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase", "aln": "MANLSPFVYWSQTKQTLLLKVDLKDAKGAIADFSPVSVNFSANGHGARGVNAYKFELHFYALIDDENATFVVSDNKIELQIRKLEPEWWPRLVATPQKPHWLKIDFDRWRTEDDVEVEEKPRDVRQDYEKEYADLQKRELGYIKEKTKKVYMIFYNLAMFVGYLYIMVVMGVLYYRDGVDSIGKTYANVGNAFKFIQLLQYLEVMHPMFGYTKGSPVVPFFQVSGRNFILFLMIDMEPRMYAKPVVFYVFIIWSLVELVRYPYYLAQLLGREVGLLTWLRYTIWIPLYPMGILCEGIIVLRNIPYIEETKR-FTVEMPNPWNITFDMVLFLKIYLMLLIIPGSYLVMS----HMAKLRSKKLGKGRAKRQQHLHAD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:: * * * *: :*:. * . : * *: *: :. : * :. **::* * . . *:*: * .:** :* .. * :* * :*.:: ::**.: : ::* : *: *: :*:* : : *.: : :**: * :. * : .: ::::*.: : . * . : ", "identical_positions": 39, "similar_positions": 66, "identity": "10.37%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3630", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M9PFL7-1", "uniprot_id": "A0A8M9PFL7_DANRE", "id": "A0A8M9PFL7-1", "name": "", "aln": "----MIMGSTLAKCAATDLAIQWVGWALACSFKTEKFYDLAGSGTFILLAHLSRVWGGSG------HLRQNVQTGLVTAWGLRLGTFLFLRILKEGQDRRFNNVRDSPGTFFVYWTMQALWVFVTLLPTLILNSERRDEPLGPR-----DYIGWGIWGLGFATEAIADQQKWNFKNDPDNVGKFIHHGLWAYSRHPNYLGEILQWSGLFLSASSIMQGPQYLSALSPLFVWFLLRHVSGIPILEKQAMKKWGSDPAFQNYVKNTPLLWPFPKVKGE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PET5-1", "uniprot_id": "M9PET5_DROME", "id": "M9PET5-1", "name": "", "aln": "MAVNVLDYDHFAISAIVVGSLQLVFFLINSVLQMDKLTDFAGGVNFIIISLLTFFLGQIDRPSKAYDSRQLMVTLFVCLWGARLSGYLLYRIVKLGRDKQFEDTRRNIIRYAVFWTFQAVWVYIVSLPVIIINSPRHSQPRAPKTMTTLDSTGTGMFIVGLLAETYADLQKFSFRQDPANQGKFCNDGLWSVSRHPNYFGEVVIWWGIFAISLNVISGHEWVAIASPIFTTMIILFLSGIPLRERSADEKYKDQLEYRKYKASTSPLIPVPPAVYVEVPSALKFILCCEFPIYDSMRIQKDLSPYSLSIARSHSHIXQSVAHSSSAAGVGQMNAHGHSVGHSLHRGQCYGANGGDAESHQNCGGSCRNVHVKSNPYQCEAGYGHYPVCHTDDDTDDGIIYMDRTHFYHDQEQAHVVKSVAVPSTKCSYLAEEELASDYDEDVPAIDLSKATSVESLGTRVQTEHAVNADGLPVTVTTIL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . :* .* . ::* * : : . :: :*: *:**. .**::: *: . * . . ** : * :* ** **. :*: **:* *:*::*::.* . : *:**:**:**::. **.:*:** *:.:* .*: * * *:: :*: :*: ** **:.*::** * *** :.***: ******:**:: * *:* : .::.* :::: **:*. ::: .:****: *:.* :*: .: :::* .*. * *.* . ", "identical_positions": 89, "similar_positions": 100, "identity": "18.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3633", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O75326-1", "uniprot_id": "SEM7A_HUMAN", "id": "O75326-1", "name": "Semaphorin-7A", "aln": "MTPPPPGRAAPSAPRARVPGPPARLGLPLRLRLLLLLWAAAASAQGHLRSGPRIFAVWKGHVGQDRVDFGQTEPHTVLFHEPGSSSVWVGGRGKVYLFDFPEGKNASVRTVNIGSTKGSCLDKRDCENYITLLERRSEGLLACGTNARHPSCWNLVN---GTVVP-LGEMRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGE-SELYTSDTVMQNPQFIKATIVH-QDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDKVFRTSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYS------SERSVLQSINPAEPHKECPNPKPDKAPLQKVS--LAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIENLTAQQYGHYFCEAQEGSYFREAQHWQLLPEDGI-MAEHLLGHACALAASLWLGVLPTLTLGLLVH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QUR8-1", "uniprot_id": "SEM7A_MOUSE", "id": "Q9QUR8-1", "name": "Semaphorin-7A", "aln": "MTPPPPGRAAPSAPRARVLSLPARFGLPLRLRLLLVFWVAAASAQGHSRSGPRISAVWK---GQDHVDFSQPEPHTVLFHEPGSFSVWVGGRGKVYHFNFPEGKNASVRTVNIGSTKGSCQDKQDCGNYITLLERRGNGLLVCGTNARKPSCWNLVN---DSVVMSLGEMKGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGE-SELYTSDTVMQNPQFIKATIVH-QDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATNRNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDRVFRTSSLKGYHMGLPNPRPGMCLPKKQPIPTETFQVADSHPEVAQRVEPMGPLKTPLFHSKYHYQKVVVHRMQASNGETFHVLYLTTDRGTIHKVVESGDQDHSFVFNIMEIQPFHRAAAIQAISLDADRRKLYVTSQWEVSQVPLDMCEVYSGGCHGCLMSRDPYCGWDQDRCVSIYS------SQRSVLQSINPAEPHRECPNPKPDEAPLQKVS--LARNSRYYLTCPMESRHATYLWRHEENVEQSCEPGHQSPSCILFIENLTARQYGHYRCEAQEGSYLREAQHWELLPEDRA-LAEQLMGHARALAASFWLGVLPTLILGLLVH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FBE1-1", "uniprot_id": "E7FBE1_DANRE", "id": "E7FBE1-1", "name": "", "aln": "--------MIRHYSSLKFKGNLAYPWLIYGACFQCVFCSCNPRLTLKQDNAP--------------LNYNTNYSHTVLFHEEGSKSLFVGGSNIVLHFDVDSYEILENFTLNANLPR---CGESSCENVVTVIETFQNCKFVCGTNGEEPQCWELYPRESNHSVVKSVEGTGISPHSSEQNSLSLVADGDLYAAAP-LYSDGTLLQFRRKAGKRINVWMHDQWVSEPTFISSFLAKRKNDSLNEKIYVLFREKNSDTSPEADPWISRVARVCKIDEGGSKQFLQNIWTSFLKARLVCGIPKESLYFNRLQDVFVQH--AEDWRDSLVYALFSSSWNSTAVCIYSLADLDDIFEKSNYKGFSEAIPNPRPGKCVENSNSLPIPTLKIIKDYPEMKDWIHPIQ-KDTPFFTSSKNFTKIVVDQIRALDENVYNVLLLATDDGMIFKILQHGSK----PFIISETHLCNGCAPIQSMKLDSKKRKLFVGYPGQMSVLELQRCQDYGASCEECVLSRDPYCAWSEKGCTSQTRGGIQNISDGNVTKVCDHKSVGRVRRDAQQSSTAPSRIQHTVATDVPFYLSCPVDSHHASYRWEHGG---KSNPCQQTQSEYLLLIPAMTAENYGNYSCVSQERDYIKVVREYELLAKSVFNDAFKLKIQDRQLMVAFVTSAFYLCSL-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 193, "similar_positions": 238, "identity": "28.34%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3647", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TT49-1", "uniprot_id": "MRCKB_RAT", "id": "Q7TT49-1", "name": "Serine/threonine-protein kinase MRCK beta", "aln": "-------------MSAKVRLKKLEQLLLD-----------GPWRNESSLSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKPFTQLVKDMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTD---VSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPDVSSPSDTSNFDVDDDVLRNIEILPPGSHTGFSGLHLPFIGFTFTTESCFSDRGSLKSMIQSNTLTKDEDVQRDLENSLQIEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSTRALGNSNRDKEIKRLNEELERMKSKMADSNRLERQLEDTVTLRQEHEDSTQRLKGLEKQYRLARQEKEELHKQLVEASERLKSQTKELKDAHQQRKRALQEFSELNERMAELRSQKQKVSRQLRDKEEEMEVAMQKIDSMRQDIRKSEKSRKELEARLEDAVAEASKERKLREHSESFSKQMERELETLKVKQG-GRGPGATLEHQQEISKIRSELEKKVLFYEEELVRREASHVLEVKNVKKEVHESESHQLALQKEVLMLKDKLEKSKRERHSEMEEAIGAMKDKYERERAMLFDENKKLTAENEKLCSFVDKLTAQNRQLEDELQDLASKKESVAHWEAQIAEIIQWVSDEKDARGYLQALASKMTEELETLRSS-SLGSRTLDP-LWKVRRSQKLDMSARLELQSALEAEIRAKQLVHEELRKVKDTSLAFESKLKESEAKNRELLEEMQSLKKRMEEK-----FRADTGLKLPDFQDPIFEYFNTAPLAHDLTFR-----------------TSSASDQETQASKLDLSPS---------VSVATSTEQQEDAARSQQRPSTVPLPNTQALAMAGPK-----PKAHQFSIKSFPSPTQCSHCTSLMVGLIRQGYACEVCAFSCHVSCKDSAPQVCPIPPEQSKRPLGVDVQRGIGTAYKGYVKVPKPTGVKKGWQRAYAVVCDCKLFLYDLPEGKSTQPGVIASQVLDLRDDEFAVSSVLASDVIHATRRDIPCIFRVTASLLGSPSKTSSLLILTENENEKRKWVGILEGLQAILHKNRLRSQVVHVAQEAYDSSLPLIKTVLAAAIVDGDRIAVGLEEGLYVIELTRDVIVRAADCKKVYQIELAPKEKLILLLCGRNHHVHLYPWTSFDGAEASNFDIKLPETKGCQLIATGTLR--KSSSTCLFVAVKR-----LVLCYEIQRTKPFHRKFNEIVAPGHVQWMAMFKDR-LCVGYPSGFSLLSIQGDGQPLDLVNPADPSLAFLSQQSFDALCAVELKS------EEYLLCFSHMGLYVDPQGRRSRTQELMWPAAPVACSCSSSHVTVYSEYGVDVFDVRTMEWVQTIGLRRIRPLNSDGSLNLLGCEPPRLIYFKNKFS-GTVLNVPDTSDNSKKQMLRTRSKRRFVFKVPEEERLQQRREMLRDPELRSKMISNPTNFNHVAHMGPGDGMQVLMDLPLSAAPTA-------------------------------QEE-------------KQGPAPTGLPR---------------------QLPSRNKPYVSWPSSGGSEPGVPVPLRSMSDPDQDFDKEPDSDSTKHSTPSNSSNPSGPPSPNSPHRSQLPLEGLDQPACDA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TT50-1", "uniprot_id": "MRCKB_MOUSE", "id": "Q7TT50-1", "name": "Serine/threonine-protein kinase MRCK beta", "aln": "-------------MSAKVRLKKLEQLLLD-----------GPWRNDSALSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKPFTQLVKDMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQWITALHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTD---VSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPDVSSPSDTSNFDVDDDMLRNIEILPPGSHTGFSGLHLPFIGFTFTTESCFSDRGSLKSMTQSNTLTKDEDVQRDLENSLQIEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSTRALGNSNRDKEIKRLNEELERMKSKMADSNRLERQLEDTVTLRQEHEDSTHRLKGLEKQYRLARQEKEELHKQLVEASERLKSQTKELKDAHQQRKRALQEFSELNERMSELRSLKQKVSRQLRDKEEEMEVAMQKIDSMRQDLRKSEKSRKELEARLEDAAAEASKERKLREHSESFCKQMERELEALKVKQG-GRGPGAASEHQQEISKIRSELEKKVLFYEEELVRREASHVLEVKNVKKEVHDSESHQLALQKEVLMLKDKLEKSKRERHSEMEEAIGTVKDKYERERAMLFDENKKLTAENEKLCSFVDKLTAQNRQLEDELQDLASKKESVAHWEAQIAEIIQWVSDEKDARGYLQALASKMTEELETLRSS-SLGSRTLDP-LWKVRRSQKLDMSARLELQSALEAEIRAKQLVQEELRKVKDSSLAFESKLKESEAKNRELLEEMQSLRKRMEEK-----FRADTGLKLPDFQDSIFEYFNTAPLAHDLTFR-----------------TSSASDQETQASKMDLSPS---------VSVATSTEQQEDMARPQQRPSPVPLPSTQALAMAGPK-----PKAHQFSIKSFPSPTQCSHCTSLMVGLIRQGYACEVCAFSCHVSCKDSAPQVCPIPPEQSKRPLGVDVQRGIGTAYKGYVKVPKPTGVKKGWQRAYAVVCDCKLFLYDLPEGKSTQPGVVASQVLDLRDEEFAVSSVLASDVIHATRRDIPCIFRVTASLLGSPSKTSSLLILTENENEKRKWVGILEGLQAILHKNRLKSQVVHVAQEAYDSSLPLIKAVLAAAIVDGDRIAVGLEEGLYVIELTRDVIVRAADCKKVYQIELAPKEKIAILLCGRNHHVHLYPWSSFDGAEASNFDIKLPETKGCQLIATGTLR--KSSSTCLFVAVKR-----LILCYEIQRTKPFHRKFSELVAPGHVQWMAVFKDR-LCVGYPSGFSLLSIQGDGPPLDLVNPTDPSLAFLSQQSFDALCAVELKS------EEYLLCFSHMGLYVDPQGRRSRMQELMWPAAPVACSCSPTHVTVYSEYGVDVFDVRTMEWVQTIGLRRIRPLNSDGSLNLLGCEPPRLIYFKNKFS-GTILNVPDTSDNSKKQMLRTRSKRRFVFKVPEEERLQQRREMLRDPELRSKMISNPTNFNHVAHMGPGDGMQVLMDLPLSAAPTV-------------------------------QEE-------------KQGPTPAGLPR---------------------QPPSRSKPYVSWPSSGGSEPGVPVPLRSMSDPDQDFDKEPDSDSTKHSTPSNSSNPSGPPSPNSPHRSQLPMEGLDQPSCDA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5S2-1", "uniprot_id": "MRCKB_HUMAN", "id": "Q9Y5S2-1", "name": "Serine/threonine-protein kinase MRCK beta", "aln": "-------------MSAKVRLKKLEQLLLD-----------GPWRNESALSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKPFTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTD---VSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPDVSSPSDTSNFDVDDDVLRNTEILPPGSHTGFSGLHLPFIGFTFTTESCFSDRGSLKSIMQSNTLTKDEDVQRDLEHSLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSSRALSNSNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQEKEELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQMESELEALKVKQG-GRGAGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVKNVKKEVHDSESHQLALQKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDENKKLTAENEKLCSFVDKLTAQNRQLEDELQDLAAKKESVAHWEAQIAEIIQWVSDEKDARGYLQALASKMTEELEALRSS-SLGSRTLDP-LWKVRRSQKLDMSARLELQSALEAEIRAKQLVQEELRKVKDANLTLESKLKDSEAKNRELLEEMEILKKKMEEK-----FRADTGLKLPDFQDSIFEYFNTAPLAHDLTFR-----------------TSSASEQETQAPKPEASPS---------MSVAAS-EQQEDMARPPQRPSAVPLPTTQALALAGPK-----PKAHQFSIKSFSSPTQCSHCTSLMVGLIRQGYACEVCSFACHVSCKDGAPQVCPIPPEQSKRPLGVDVQRGIGTAYKGHVKVPKPTGVKKGWQRAYAVVCDCKLFLYDLPEGKSTQPGVIASQVLDLRDDEFSVSSVLASDVIHATRRDIPCIFRVTASLLGAPSKTSSLLILTENENEKRKWVGILEGLQSILHKNRLRNQVVHVPLEAYDSSLPLIKAILTAAIVDADRIAVGLEEGLYVIEVTRDVIVRAADCKKVHQIELAPREKIVILLCGRNHHVHLYPWSSLDGAEGS-FDIKLPETKGCQLMATATLK--RNSGTCLFVAVKR-----LILCYEIQRTKPFHRKFNEIVAPGSVQCLAVLRDR-LCVGYPSGFCLLSIQGDGQPLNLVNPNDPSLAFLSQQSFDALCAVELES------EEYLLCFSHMGLYVDPQGRRARAQELMWPAAPVACSCSPTHVTVYSEYGVDVFDVRTMEWVQTIGLRRIRPLNSEGTLNLLNCEPPRLIYFKSKFS-GAVLNVPDTSDNSKKQMLRTRSKRRFVFKVPEEERLQQRREMLRDPELRSKMISNPTNFNHVAHMGPGDGMQVLMDLPLSAVPPS-------------------------------QEE-------------RPGPAPTNLAR---------------------QPPSRNKPYISWPSSGGSEPSVTVPLRSMSDPDQDFDKEPDSDSTKHSTPSNSSNPSGPPSPNSPHRSQLPLEGLEQPACDT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P2Q2-1", "uniprot_id": "A0A8M9P2Q2_DANRE", "id": "A0A8M9P2Q2-1", "name": "non-specific serine/threonine protein kinase", "aln": "-------------MSAKVRLKKLEQLLLD-----------GHQKNDKSLSVETLLDILICLYNECSNSPLKREKHVTDFLEWVKPFTTTVKEMRLHRDDFEMLKVIGRGAFGEVAVVKMKHTERVYAMKILNKWEMLKRAETACFREERNVLVNGDCQWITTLHYAFQDDNYLYLVMDYYVGGDLLTLLSKFEDRLPEDMAKFYVAEMVLAIHSIHQQRYVHRDIKPDNVLLDMNGHIRLADFGSCLKMMQDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHITD---VSEDAKDLIQRLICSRERRLGQHGIEEFRKHAFFSGIDWENIRNMEAPYIPDVSSPSDTSNFDVDDDVLKNPDIAPPVSHTGFTGQHLPFVGFTYTTESCFSDGGSMRGVALSDGGTG-EDLQ---DGGMQVEAFEKRIRCLEQEKLELNRKLQESTQAVQSLHGSGRGAGTLGRDKEIKKLNEEIDRLKKKLADSDRLEHQLEEAVTLRQDFESSSTKLKALDKQVKALKLEKEDIHKQLVESLDRLKSQTKELKDAHQQRKLAMQEFSEVNERMAELRSQKQRLSRQLRDKEEEMEVVMQKIDAMRQDIRKTEKARKELESQLEDARAEASKERKLREHSEVYSKQLESELETLKVKQGTGRASGLGAETQQELTKLKSELDKKGLYYEEELVRREASHTTEMKNLRKELQDSEGQQLSLHKELLALKEKLEKAKRERQIEMEEAINALKEQYERERNLMSEDNRKLTAETDRLCSFVDKLTAQNRQLEDELQELASKKESVAHWEAQIAEIIQWVSDEKDARGYLQALASKMTEELESLRSS-SLGSRTLDP-LWKVRRSQKLDMSARLELQSALEAEIRAKQLVHDELRKVKAANISFESKLKDTEAKNRELEEQLENMKKEMEESR----SRSDKGLKLPDFQDSIFDYFNTSPLAHELTFRDSVSSSSASSLLAFWDETSSVGDVDVAPQKTDIPPS---------SPSAAT--EQDEAVKPQATTPATPSPMYQP-TLTAPK-----PKAHQLSIKTFSSPTQCTHCTSLMVGQMRQGYACEVCSFICHVSCKDNAPQLCPIPPEQTKRPLGIDVQRGIGTAYKGFVRIPKPTGVKKGWQRAYAVVCDCKLFLYEVPEGKSTQPVVMASQVLDLRDEEFSVSSVLASDVIHANHKDVPCIFRVTSSALKSSIRPVPLLILAESEAEKRKWVGILEGLQSILAKNRLKNRVVHVLHEAYDSSLPAIKTTLSAAIVDRERIVLGTEDGLFVVEITRDVIVRAADCKKVCQIELIPKEKMVALLSGRNRHVHLYPWAALEGAEGG-FDTKLTDTRGCQAMTIGNLR--PGGPACLFAGVKR-----QVFCYEITRAKPHHRKLWEVQAPGVVQWLGIIRER-ICVGYPSGFALLAMQGESSPVSLVSPGDPSLAFLAQQPLDALHAMEVGS------NELLLCFSQLGVYVDATGRRSRTQELMWPSTPLACSSNSNCLTVYSDYGVDVFDVHTMEWVQTISLRKIRPLNVEGSLNLLSIEQPHLIYFSNNSSDGCDLAIPETSDNSKKLMVRTRSKRKFLFKVPEEERLQQRREMLRDPEMRSKLISHPTNFNHVAHMGPGDGMQVLMDLPLPSETPSPSSSRHHALISPPTNFEHVYHMSPVSAGLYLQKEPSSQQSLLQFSSSSSSPSTSSLGRSVMPSSQDDLSKDKPRPLSSISRQQRSKTHITRTASGGGDFGGAGSSRSISDQDQDYEREPDSDSTKHSTPSNSSNPSSPPSPNSPHRSQLTLDSLDQSLDG-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1B0-1", "uniprot_id": "GEK_DROME", "id": "Q9W1B0-1", "name": "Serine/threonine-protein kinase Genghis Khan", "aln": "MEYESSEISDITTGSCKKRLTFLKCILSDTTSDQKWAAEFGEDTEGHQFSLDYLLDTFIVLYDECSNSSLRREKGVSDFLKLSKPFVHIVRKLRLSRDDFDILKIIGRGAFGEVCVVQMISTEKVYAMKILNKWEMLKRAETACFREERDVLVFGDRQWITNLHYAFQDNINLYLVMDYYCGGDLLTLLSKFEDKLPEDMAKFYITEMILAINSIHQIRYVHRDIKPDNVLLDKRGHVRLADFGSCLRLDKDGTVQSNVAVGTPDYISPEILRAMEDGKGRYGTECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHQNCFNLPSQETLNYKVSETSQDLLCKLICIPENRLGQNGIQDFMDHPWFVGIDWKNIRQGPAPYVPEVSSPTDTSNFDVDDNDVRLTDSIPPSANPAFSGFHLPFIGFTFS---------------------------------------------------------LTSSSTLDSKKNQSSGFG-----------DDTLDTISS---------PQLAILPSNNSETPVDSVQLKALNDQLAALKQEKAELSKQHNEVFERLKTQDSELQDAISQRNIAMMEYSEVTEKLSELRNQKQKLSRQVRDKEEELDGAMQKNDSLRNELRKSDKTRRELELHIEDAVIEAAKEKKLREHAEDCCRQLQMELR----KGSSSVETTMPLSISSEMS--SYEIERLELQFSEKLSHQQTRHNMELEALREQFSELENANLALTKELQQTQERLKYTQMESITDSAETLLELKKQHDLEKSSWFEEKQRLSSEVNLKSKSLKELQAED---DEIFKELRMKREAITLWERQMAEIIQWVSDEKDARGYLQALATKMTEELEYLKHVGTFNNNGVDNKNWRNRRSQKLDKMELLNLQSALQREIQAKNMISDELSQTRSDLISTQKEVRDYKKRYDSILHDFQKKETELRDLQKGGLEYSESFLNKSTHHGLSSAFFRDMSKNSEIIDS-----------------AESFGNESGDNFTPNFFQSGNSGMLFNYEPKYAGKNNKDHSSMKEASVSDLSREESDQLVKESQKKVPGNTAIHQFLVRTFSSPTKCNHCTSLMVGLTRQGVVCEICGFACHTICCQKVPTTCPVPMDQTKRPLGIDPTRGIGTAYEGYVKVPKSGVIKRGWIRQFVVVCDFKLFLYDISPDRCALPSVSVSQVLDMRDPEFSVGSVRESDVIHAAKKDVPCIFKIKTALIDGG-LSLNTLMLADNESEKSKWVIALGELHRILKRNSLPNTAIFKVNEILDNTLSLIRNALCSVIIYPNQILLGTEDGLFYINLDQYEIARIGESKKILQLWYIEEEQILVILCGKQRNLRLLPIRALEASDVE--WIKVVESKNCISACTGIIRRFPNIVYSFIIALKRPNNHTQIVVYEINRTRTRHQKTCEFTIGYMAQHLQILSDMRLVVAHQSGFTAYFLRGEATAMSLVHPENQLCAFLNYSGVDAVRVIEILCPSGGNFGEYLLVFQTLAIYVDLQGRKSRDREIMYPAFPTYITFCDGHLLVFSDTHLDIFNTQTAEWVQSIGLKQSLPLNNLGNVVLSSVNDTPLIVYLSNIH---TKGLLQYRDGNRKGLP--SIKRRFSIREINKTIKSDR---------RSKMISAPTNFNHISHMGPGDGIQNQRLLDLPTTLET--------------------------------------------------------------------------------------------ADQACSPIIHSLSCIPQSRKSNFLEQVDANSDDYG---NDNIISRTPSPMASS----FMDGLSNND---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.* **. *: :* * * : :*:: *** :: ** ***:*.*:*:* *::**: ***. *:.::* *:**:::*:*********.**:* **::************************:*** ** **** *******: ******** *************:******:**: **:***.**** :************** .**:*********:: .******.**************:***** *:**.************************************:: *::**: * *** ::**: :*** *.****:**::* .*.:* *::*:***: ***:*:****:*********: :: : ** ::..*:* ****:***:: *:.:::* :.. . . :: :: :.. ** : ..: .: :*:.*:.* : ** :: ** * :***:* .**:** .**: *: *:**:.*:::*** **::***:******:: . ** *::*:::*:::* *:*** :::** **:**:*****:* .:*:: **. * . . . . ..*:: *::: * :.*:* :::: * *:: ::::. : *. :*:* **: :::*: :: * : *:: :*.::: *: :::::*::* : .. :.:* *:: :: :::* *:*::: ** *:*********************:******* *: ::... :* *: ******* *:*****: **:**::: :** :.: :: :.:::: : : .: .::: ...:.: ::. *: . .:. :*. . :: :.* .: . . : * . : :::. . . : . . * . **: :::*.***:*.******** *** .**:*.* **. * : .* **:* :*:*****:* *******:*.*::**. :*:** * :.**** *****::. .:.: * * .*****:** **:*.** ****** ::*:****::.:: : . . *:*::.* ** *** * *: ** :* * . .:. * *.:*. *: * :.*: ::* :* *:**: ::: : *.* .:.**: *: .*:: :*.*::::::* * :::.:: *: :::.* . :: . .:: .:** :. *** *::. *:* *. .* : :: : : *.: *** ::*:. .:.** * : *** . .**: .:*: . * ** *. :.:*** **::* :*:*:*: * : : *:*: :*:*:.:* ****:*.*:: *** *.: * . : . ** : .: : : *..:* : **:* :: :: .:* ***:** ******::*******:* * *.: :. . . .. ..:: .: *::* .:. *.. * .*** :. ::.*.: ", "identical_positions": 631, "similar_positions": 514, "identity": "33.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3654", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G2S5-1", "uniprot_id": "A0A8I6G2S5_RAT", "id": "A0A8I6G2S5-1", "name": "Transcription factor Sp8", "aln": "----MLAATCNKIGSPSPSP-SSLSDSSSSFSKG----FHPWKRSS--SSSSGSCNVVGSSLSSFGVSGASRNGGSSSAAAAAAAAAAAAAALVSDSFSCGGSPGSSAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGGSGAHSQDSS-HQPVFISKVHTSVDGLQGIYPRVGMAHPYESWFKPSHPGLGAAADVGSAGASSWWDVGAGWIDVQNPNGAAALPG--SLHPAAGGLQTS----LHSPLGGYNSD--YSGLSHSAFSSGASSHLLSPAGQHLMDGFKP-------VLPGSYPDSAPSPLAGAGSSMLSAGPAAPLGGSPRS----SARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHVKTHS--------------------------------------------------GGGG---SAGSG------------GGKKGSDTDS--------------------------------EHSAAGSPP------------------CHSPELLQPPEPGHRNGLE------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMJ8-1", "uniprot_id": "SP8_MOUSE", "id": "Q8BMJ8-1", "name": "Transcription factor Sp8", "aln": "----MLAATCNKIGSPSPSP-SSLSDSSSSFGKG----FHPWKRSS--SSSSGSCNVVGSSLSSFGVSGASRNGGSSSAAAAAAAAAAAAAALVSDSFSCGGSPGSSAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGGSGAHSQDSS-HQPVFISKVHTSVDGLQGIYPRVGMAHPYESWFKPSHPGLGAAADVGSAGASSWWDVGAGWIDVQNPNGAAALPG--SLHPAAGGLQTS----LHSPLGGYNSD--YSGLSHSAFSSGASSHLLSPAGQHLMDGFKP-------VLPGSYPDSAPSPLAGAGSSMLSAGPAAQLGGSPRS----SARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHVKTHS--------------------------------------------------GGGG---SAGSG------------GGKKGSDTDS--------------------------------EHSAAGSPP------------------CHSPELLQPPEPGHRNGLE------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IXZ3-3", "uniprot_id": "SP8_HUMAN", "id": "Q8IXZ3-3", "name": "Transcription factor Sp8", "aln": "----MLAATCNKIGSPSPSP-SSLSDSSSSFGKG----FHPWKRSS--SSSSASCNVVGSSLSSFGVSGASRNGGSSSAAAAAAAAAAAAAALVSDSFSCGGSPGSSAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGGSSAHSQDGS-HQPVFISKVHTSVDGLQGIYPRVGMAHPYESWFKPSHPGLGAAGEVGSAGASSWWDVGAGWIDVQNPNSAAALPG--SLHPAAGGLQTS----LHSPLGGYNSD--YSGLSHSAFSSGASSHLLSPAGQHLMDGFKP-------VLPGSYPDSAPSPLAGAGGSMLSAGPSAPLGGSPRS----SARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHVKTHS--------------------------------------------------GGGGGGGSAGSGS-----------GGKKGSDTDS--------------------------------EHSAAGSPP------------------CHSPELLQPPEPGHRNGLE------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P0J3-1", "uniprot_id": "SP8_DANRE", "id": "Q6P0J3-1", "name": "Transcription factor Sp8", "aln": "----MLAATCNKIGSPSPSP-SSISDNSSSFGKG----FHPWKRAT--ASSCS----LGSSLSSF-----TRNGGG-----------------LSDSFGTNTSTGSSAFSLTSG-----------TSSNSHFGNDYSVFQTS-VSN---------------NSQEPS-HQPMFISKVHTSVDSLQSIYPRMSVAHPYESWFKSSHPGI-PTGDVGTTGASAWWDVGAGWIDVQNPNG-AALQT--SLH--SGGLQTS----LHSPLGGYNSD--YSSLSHSAFSTSASPHLLT-TGQHLMDGFKP-------VLS-SYPDSSPSPLGGAGGSMLTGGPTASLAGSPRS----SARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHVKTHS--------------------------------------------------AGGS--SGSGSGA----------SGGKRGSDTDS--------------------------------EHSVPGSPS------------------CHSPDLLQAPESVPTTGMNGRASSLD-----------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PJG1-1", "uniprot_id": "M9PJG1_DROME", "id": "M9PJG1-1", "name": "", "aln": "MLTDMTPTAGQLYGSQIPAMGMNISNIATHLQKPQVNPDHPSLRGTPLAMLAAQCNKLSNKSPPPLADAAVGKGFHPWKKSPNSPAAGSSGSSGGGGGGGGSSAGQHSPCAISAASSSSSSGSSGGQSSRSLSSSASTMVNITASRPLASSCAAVGGGSTGSSSSASGSQSSSTASAVAAAYGGDLYFPNTSTSNMDNHHMHQGLLGKVEAGAAAFGGVYSRHPYDWPFNAVTHKEAASVNSGWWDMHSAAGSWLDMGGAGMHSTMANYASENYSSALSHSLLGSGQ--HLLQDTYKSMLPGQGVGVGVGVGMGGFSLPHSSPSAAAAAAATAAAAAGGSPQGGSPSTPSPRSQRRYAGRATCDCPNCQEAERLGPAGVHLRKKNIHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLAKHVKTHNGTANHQANGHNGGLKKGSSESCSDSEEAANQSGESNGLGGVGSGPQTGGAGGGGGGSSSGNGAGTLAVSGSVTTGAGAGSGTGSSNSNSNSGGSSGSVSGSVSGSGSHPGTPTSLHAHSANGTSSSLLGGGLHLATPHQMVAAGGSPVMLHQQQQQQQHQQQQQQQQQQQHQQQQQQQHQQQQQQHQQQQQQHHQQQQQHHHQQFGQQQHPHAHHLHHHAHHAHHLATGGSPGLDPSSLVDIKPPMVXGSLGPFLFTN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .:: : ** *: .:*: :: : * ** *.: : .. :... .. :* ... . . *.*. : . *. *. :... *.: .* *.. * *. :.. ::. . : :*. . :: : :: . * :. .. *. : . : * : :. :. .:* :*. :**.:..* *: *.**** :.:. *** : : :: * : * *.*:**. ..*..: :.. : .*** : * ***:********************. **:*.:****************************************************************************:******. .**. .:*.* *. **.*.* **. *:.. ** :*: : : ", "identical_positions": 171, "similar_positions": 131, "identity": "23.49%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3656", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6A4J8-1", "uniprot_id": "UBP7_MOUSE", "id": "Q6A4J8-1", "name": "Ubiquitin C-terminal hydrolase 7", "aln": "-----------MNHQQQQQQQQKAGEQQLSE---------PEDMEMEAGDTDDPPRITQNPVING------------NVTLSDGHSNAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVR-NLPWKIMVMPRFYPDRPHQKSVGFFLQCNAES-----------DSTSWSCHAQAVLKIINYRDDDKSFSR-RISHLFFHEENDWGFSNFMAWSEVTDPEKG----FIDDDKVTFEVFV-QADAPHGVAWD------SKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKDVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPAN----------YILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGG---HDDDLSVR-----------HCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEE------------KVRYTVFKVLKNSSLAEFVQSLSQTMGFPQDQ-IRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASG--------------------------------------------------ATLPKFDK----------DHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSE--LPTAKEYFRDLYHRVDVIFCDKTIPND---------PGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQG-YRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREE-EITLYPDKHGCVRDLLEECKKAVELGDKASGRLRLLEIVSYKIIGVHQEDELLECLS---------PATSRTFRIEEIPLDQVDIDKENEML------------------------------ITVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4VSI4-1", "uniprot_id": "UBP7_RAT", "id": "Q4VSI4-1", "name": "Ubiquitin C-terminal hydrolase 7", "aln": "-----------MNHQQQQQQQQKAGEQQLSE---------PEDMEMEAGDTDDPPRITQNPVING------------NVALSDGHSNAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVR-NLPWKIMVMPRFYPDRPHQKSVGFFLQCNAES-----------DSTSWSCHAQAVLKIINYRDDDKSFSR-RISHLFFHKENDWGFSNFMAWSEVTDPEKG----FIDDDKVTFEVFV-QADAPHGVAWD------SKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPAN----------YILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGG---HDDDLSVR-----------HCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEE------------KVRYTVFKVLKNSSLAEFVQSLSQTMGFPQDQ-IRLWPMQARSNGTKRPAMLDNEADGSKTMIELSDNENPWTIFLETVDPELAASG--------------------------------------------------ATLPKFDK----------DHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSE--LPTAKEYFRDLYHRVDVIFCDKTIPND---------PGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQG-YRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREE-EITLYPDKHGCVRDLLEECKKAVELGDEASGRLRLLEIVSYKIIGVHQEDELLECLS---------PATSRTFRIEEIPLDQVNIDKENEML------------------------------ITVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q93009-1", "uniprot_id": "UBP7_HUMAN", "id": "Q93009-1", "name": "Ubiquitin C-terminal hydrolase 7", "aln": "-----------MNHQQQQQQQ-KAGEQQLSE---------PEDMEMEAGDTDDPPRITQNPVING------------NVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVR-NLPWKIMVMPRFYPDRPHQKSVGFFLQCNAES-----------DSTSWSCHAQAVLKIINYRDDEKSFSR-RISHLFFHKENDWGFSNFMAWSEVTDPEKG----FIDDDKVTFEVFV-QADAPHGVAWD------SKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPAN----------YILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGG---HDDDLSVR-----------HCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEE------------KVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQ-IRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASG--------------------------------------------------ATLPKFDK----------DHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSE--LPTAKEYFRDLYHRVDVIFCDKTIPND---------PGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQG-YRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREE-EITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLS---------PATSRTFRIEEIPLDQVDIDKENEML------------------------------VTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I3ISS5-1", "uniprot_id": "I3ISS5_DANRE", "id": "I3ISS5-1", "name": "Ubiquitin carboxyl-terminal hydrolase 7", "aln": "-----------MNHHHTQQQQQKAGEQQLSE---------PEDMEMEAGDPDDPPRIPQNPVING------------NVAMADGHNNTEEDMEDDTSWRSEATFPFVVERFSRLSESVLSPPCFVR-NLPWKIMVMPRFYPDRPHQKSVGFFLQCNAES-----------DSTSWSCHAQAMLKIINYKDDEKSFSR-RISHLFFHKENDWGFSNFMSWSDVTDPERG----FVEDDKVTFEVYV-QADAPHGVAWD------SKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRRAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKHVDYRSERIEDYYDIQLSIKGKKNIFESFKDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTFPPILHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKPDVKDPAN----------YILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEATEHNYGG---HDDDLSVR-----------HCTNAYMLVYIRESKLSEVLQPVTDMDIPQQLVERLQEEKRVEAQKRKERQEAHLYMQVQMVTEDQFCGHQGNDMYDEE------------KVKYTVFKVLKSSTLAEFVQNLSQTMGFPQDQ-MRLWPMQARSNGTKRPAMLDYEADCNKSMIDLSDNENPWTIFLETVDPEMAASG--------------------------------------------------ATLPKFDK----------DHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCERAGFQQGTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDTSE--LPTAKDYFRDLYHRVDVIFCDKTIHND---------PGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQG-YRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKAIWLNSMFREE-EITLYPDKHGCVRDLLEECKKAVELSDKGSEKLRLLEIVSYKIIGVHQEDELLECLS---------PAASRTFRIEEIPLDQVDLDKENEML------------------------------IPVAHFHKEVFGTFGIPFLLKIRQGEPFREVMKRIQSMLDIQEKEFEKFKFAIVMMGRHQYINEEDYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRGRYTYLEKAIKIHN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYQ8-1", "uniprot_id": "UBP7_DROME", "id": "Q9VYQ8-1", "name": "Ubiquitin carboxyl-terminal hydrolase 7", "aln": "MEIETDQSIEAMDTQDTQEVEILTSDLQQTQQQRNSPPQLPKFKNLIQPQLHAVGAVTQLPSENGNMPPQQLLADSSSTSFGDGEAMGIDDESKEDQFRSETTFSFTVENVVQLKSQRLSPPVYVR-MLPWRIMVIP-------NDRALGFFLQCNGEN-----------DSPTWSCNAIAELRLKCHKPDAQPFTRARIKHLFYSKENDYGYSNFITWQELKDSEKS----YVHNNSITLEVHV-VADAPHGVLWD------SKKHTGYVGLKNQGATCYMNSLLQTLYFTNSLRLSVYRIPTEADDSSKSVGLSLQRVFHELQFGDRPVGTKKLTKSFGWETLDSFMQHDVQEFLRVLLDKLESKMKGTILEGTIPGLFEGKMSSYIKCKNVDYNSTRYETFYDIQLNIKDKKNIYESFQDYVAPETLEGDNKYDAGVHGLQEASKGVIFTSFPPVLHLHLMRFQYDPVTDSSIKYNDRFEFYEHINLDRYLAESE-NTLAD----------YVLHAVLVHSGDNHGGHYVVFINPKADGRWFKFDDDVVSSCRKQEAIEQNYGG---MDDEISFHA----------KCSNAYMLVYIRQSELDRVLGDITESEISSDLVERLDLEKRIEMARRKERGEANTYVSVHVILEENFEEQHKRRLFDLE------------KVHPRVFRIKQNQTVDELVDLFVRGFGVSRQR-MRMWNLCT--AQTQKFSHFDFVAEGSRTIEQISTSQKPWVIWLQLAWTDVPGP-----------------------------------------------------LPPFNP----------KTESLLFLKYYDPRNKRLNYIGCTQQPHTRRLIDLVPDVNSKLGFEPDTELTIYDEYADKKLVNLNEPIESALFIPQDHLQGHILIFEREN-VDAKLD--LPTVGDYFLDLVYRIEIIFSDKCNPNE---------PDFTLELSNRYNYDQLANAVAERLNTDPQKLQFFMCINNYKETAGNAVPYTFKGTIKDLVSYTKQSSTKRIFYQRLSLSIHELDNKKQFKCVWVSSDLKDEKELVLYPNKNDTVKGLLEEAAKKISFAENSRRKLRLLKISNHKIVAVCKDDIPLDTLLKSNESITTAQGAQKTFRIEEVPAEDMQLA-ENEFL------------------------------IPVAHFSKELYNSFGIPFLTKARQGEPYGALKQRIQRRLNVQDKEWENYKFCVISMGHNADVNDN----TPVDLEVYRSWTSGQLPFFGLDHINKSRKRSSLNFSEKAIKIYN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50101-1", "uniprot_id": "UBP15_YEAST", "id": "P50101-1", "name": "Ubiquitin carboxyl-terminal hydrolase 15", "aln": "--------------------------------------------MSSEDELGSIGTVFPG------------------SPIDKSIGSILPQFDEEVETLLEDSFTWNIPDWNELTNPKYNSPRFRIGDFEWDILLFPQ----GNHNKGVAVYLEPHPEEKLDETTGEMVPVDPDWYCCAQFAIGISRPGNGDTINLINKSHHRFNALDTDWGFANLIDLNNLKHPSKGRPLSFLNEGTLNITAYVRILKDPTGVLWHNFLNYDSKKVTGYVGFRNQGATCYLNSLLQSYFFTKYFRKLVYEIPTEHESPNNSVPLALQRAFYQLQVSDIPLDTLELTRSFGWDTAESFTQHDVQELNRILMDRLENNMKGTPVEGKLNEIFVGKMKSYIKCINVDYESARVEDFWDLQLNVKNFKNLQESFDNYIEMELMNGENQYAAQDYGLQDAQKGVIFESFPPVLHLQLKRFEYDFNYDQMVKVNDKYEFPETIDLSPFVDKDVLKKTLDSENKDKNPYVYNLHGVLVHSGDISTGHYYTLIKPGVEDQWYRFDDERVWRVTKKQVFQENFGCDRLPDEKVRTMTRGEYQNYIIQRHTSAYMLVYIRQEQEEDLLRPVLESDVPKHVITRVREEIKERETKEKEIREAHLYVTLRLHSIKEFIHYEGFDYFAHDGFRLFAEELNDSGLQQINLKVLRTTKLSDIFASIKETMNIPQERDVKYWKMDYRRNSTLRLTQPINFESVNITLQEALKKEKKRTMQTQYGEEGVASTEEDDKALLETVSFLDLFIEEPYLELQFLNKLKEASLISKAQLDDELISTIRTNLPELTKGGIEPVFATDNKSNLLFVKSYDPHTQKLLGFGHFAVNQLQQLSDISAIIED--SISSNEKLTFYEEVQP---GTINEIYMKETIYDADIDTGDIVSFEVPGAVLPDTFPVYATIKDFYSYLRYRVKLKFSKFDGSSEEYGVSNEIPESFEFWISAYAPYDDLARMVSKYAHVKPEYLKIIALYS-----NGRFVLKSTSLLNDYLLKDFNCDQIPPFAFEVLSVPLKELERLRPIKLYWLKNSYIHYQCFEFEVANDYTESQFLEKVQHKIGFTDEEKENILLWTNTNFQFQGLLSDQNTFKDVSKHSLLFGRILPEESKLFKELNRLENVQTSSLEDFMDDENATDRPMDDEQDLGMAIEHSEDMKGRIVVVQQYFKDLENRHGISFLFNLIPDETFPKTKDRLHAKFGLGQKEFSKIKLSIGYSTEEGTVFRS--LQGFSDEELDKVILYDIMSNLDYIYMDHPDRLRSHSSYDRPMIIKN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: .. : ..: . * :* : : .*.. ..* : : * *:::* :::.:..:*: : *. .. * * * : : . : * * :.*:*::*:: .::....:. ::.:..:.: ..* . * ** *. *** *****::*******:*****: :**: :* ** :*** :...:** *:***.*::** .* *:.* :**:****:* :** ******: *:*:*.:*.:**** :**.: :* *** ***:* .***.* * * ::*:**.:*. **: *** :*: * ::*:*:* * :***:*.*** * ::**:***:* ** ** *. :* **::** * : *. :: : : : * **.******* *** . ::* :.:* :***: * *::. :.*:* *:.: : :.********:.: . :* : : ::...:: *: * : . :.** **: *: ::: .:* . : : :: ::: :. .: ::. : . :...::: :: * : * : : . . :: : .:: .: : :... ** : . . :**:* ***:.: * * :: *: . : . .: . .* :*:* ::: . : *.*: *: . .* ::: * :*:.: *.. .: .* . :* * ::*. *:: :..* *::: . *. : . . *:. : . : :: *.: : :::. : :* *:.. . : : :. :**: : : : :: .: * ..:: .: .:: :. : . .: * :::: :::: : * :: *:: . .**.** . .* : .*:: :.: :**:.: *:.: .. : . * * . :. ::::. : . ::.: * *", "identical_positions": 236, "similar_positions": 388, "identity": "18.04%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3663", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGQ7-1", "uniprot_id": "SYAC_MOUSE", "id": "Q8BGQ7-1", "name": "Alanine--tRNA ligase, cytoplasmic", "aln": "MDATLTAREIRERFINFFRRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTIDPSHPMAKLSRAANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGSWSFGDYFKELACKMALELLTQEFGIPVERLYVTYFGGDEAAGLEPDLECRQIWQNLGLDEARILPGNMKDNFWEMGDTGPCGPCSEIHYDRIGGRDAAHLVNQDDPNVLEIWNLVFIQYNRESDGVLKPLPKKSIDTGMGLERLVSVLQNKMSNYDTDLFMPYFEAIQKGTGARPYTGKVGAEDADGIDMAYRVLADHARTITVALADGGRPDNTGRGYVLRRILRRAVRYSHEKLNASRGFFATLVDVVVQSLGDAFPELKKDPEMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDCKTIPGDTAWLLYDTYGFPVDLTGLIAEEKGLVVDMNGFEEERRLAQLKSQGKGAGDEDLIMLDIYAIEELRAKGLEATDDSPKYNYQSDSSGSYVFECTVATVLALRREKMFVDEVVTGQECGVVLDKTCFYAEQGGQIYDEGYLVKVDDSSEDKTEFTVKNAQVRGGYVLHIGTIYGNLKVGDQVRLFIDEPRRRPVMSNHTATHILNFALRSVLGEADQKGSLVAPDRLRFDFTAKGAMSTQQIKKAEEIVNGMIEAAKPVYTQDCPLAAAKAIQGLRAVFDETYPDPVRVVSIGVPVSELLDDPCGPAGSLTSVEFCGGTHLRNSSHAGAFVIVTEEAIAKGIRRIVAVTGAEAQKALRKSETLKKSLSAMEAKVKAQTAPNKDVQREIADLGEALATAVIPQWQKDEQRETLKSLKKVMDDLDRASKADVQKRVLEKTKQLIDSNPNQPLVILEMESGASAKALNEALKLFKTHSPQTSAMLFTVDNEAGKITCLCQVPQNAANRGLKASEWVQQVSGLMDGKGGGKDMSAQATGKNVGCLQEALQLATSFAQLRLGDVKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49588-1", "uniprot_id": "SYAC_HUMAN", "id": "P49588-1", "name": "Alanine--tRNA ligase, cytoplasmic", "aln": "MDSTLTASEIRQRFIDFFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTIDPSHPMAKLSRAANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGSWSFGDYFKELACKMALELLTQEFGIPIERLYVTYFGGDEAAGLEADLECKQIWQNLGLDDTKILPGNMKDNFWEMGDTGPCGPCSEIHYDRIGGRDAAHLVNQDDPNVLEIWNLVFIQYNREADGILKPLPKKSIDTGMGLERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTGKVGAEDADGIDMAYRVLADHARTITVALADGGRPDNTGRGYVLRRILRRAVRYAHEKLNASRGFFATLVDVVVQSLGDAFPELKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDSKTIPGDTAWLLYDTYGFPVDLTGLIAEEKGLVVDMDGFEEERKLAQLKSQGKGAGGEDLIMLDIYAIEELRARGLEVTDDSPKYNYHLDSSGSYVFENTVATVMALRREKMFVEEVSTGQECGVVLDKTCFYAEQGGQIYDEGYLVKVDDSSEDKTEFTVKNAQVRGGYVLHIGTIYGDLKVGDQVWLFIDEPRRRPIMSNHTATHILNFALRSVLGEADQKGSLVAPDRLRFDFTAKGAMSTQQIKKAEEIANEMIEAAKAVYTQDCPLAAAKAIQGLRAVFDETYPDPVRVVSIGVPVSELLDDPSGPAGSLTSVEFCGGTHLRNSSHAGAFVIVTEEAIAKGIRRIVAVTGAEAQKALRKAESLKKCLSVMEAKVKAQTAPNKDVQREIADLGEALATAVIPQWQKDELRETLKSLKKVMDDLDRASKADVQKRVLEKTKQFIDSNPNQPLVILEMESGASAKALNEALKLFKMHSPQTSAMLFTVDNEAGKITCLCQVPQNAANRGLKASEWVQQVSGLMDGKGGGKDVSAQATGKNVGCLQEALQLATSFAQLRLGDVKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LVL2-1", "uniprot_id": "Q1LVL2_DANRE", "id": "Q1LVL2-1", "name": "Alanine--tRNA ligase", "aln": "MDSSLTAAQIREKFIDFFRRHEHQYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTIDPSHPMARLRRAANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGSWSFGDYFKHLACKMALELLTQEFGIPIERLYVTYFGGHADAGLEPDLECKQIWLDLGMEESRILPGSMKDNFWEMGDTGPCGPCSEIHYDRIGGRDAAHLVNMDDPNVLEIWNLVFIQFNRESETVLKPLPKKSIDTGMGLERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARAYTGKVGAEDTDGIDMAYRVLADHARTITIALSDGGRPDNTGRGYVLRRILRRAVRYSHEKLGAQRGFFASLVDVVVKSLGDAFPELRKDPDMVKDIINEEEAQFLKTLSRGRRILDRKIQSLGESTTIPGDTAWLLYDTYGFPLDLTALIAEERGMGVDLLAFEEEKKAAQLKSQGKGSGDEDHIMLDIYAIDELRNKGVAATDDSPKYKYTSDDNGNYEFEQAVGTVLALRRERMFVDEVITGQECGVLLDKTSFYAEQGGQSFDEGYMLRENDSAEDRMEFTVKNTQVRGGYVLHIGTVYGTLKVGDRLTLHVDEARRRPIMSNHTATHILNYGLRSVLGEADQRGSLVAPDRLRFDFTAKGAMSTDEVRRTEEIAAAMIADAKGVYALDAPLAAAKAIQGLRAVFDETYPDPVRVVSIGVPVEELLADPNSPAGSLTSIEFCGGTHLQNSSHAAPFVIVSEEAIAKGIRRIVAVTGAEAQKAQRKADALKLSLDALAEKVKAQSIPNKDVQKEIADMTESLGTAVISQWRKDEMRESLKGLKKIMDDLDRASKADVQKRVLEKTKEIIDSNPNQPLIVMEMESGASAKALNESLKMLKTNSPQTAAMLFTVDNDAGKIICLCQVPQDVANRGLKASEWVQEVCPLLDGKGGGKDMSAQATGRNTQCIQEALQLASEFARLKLGEN--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::*** :**::**:**:*:** ****************************************:* ********************************************.*****************:**********. ****.****:*** :**:::::****.*********************************** ***************:***:: :**********************************:*************.*********:******************:**:************************:****.*.*****:******:*********:***:**********.*********************:..*****************:***.*****:*: **: .****:: *********:*.** ********:*** :*: .*******:* *..*.* ** :*.**:*****:***:** *******:****.******** :****::: :**:**: ******:************:** *****:: *.:**.****:***********:.**********:*********************::::::***. ** ** **: *.********************************.*** ** .*******:********:*****..****:********************** **:::** .*..: *****: ******:****: *:*.****.**:*** **:**.***:*********************::*********:::*************:**::* :****:********:**** *******:.************:*. *:********:******:*. *:*******:.**:*:**: ", "identical_positions": 780, "similar_positions": 142, "identity": "80.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3665", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NZI5-1", "uniprot_id": "GRHL1_HUMAN", "id": "Q9NZI5-1", "name": "Grainyhead-like protein 1 homolog", "aln": "MTQEYDNKRPVLVLQNEALYPQRRSYTSEDEAWKSFLENPLTAATKAMMSINGDEDSAAALGLLYDYYKVPRERRS-STAKPEVEHPEPDHSKRNSIPIVTEQPLISAGENRVQVLKNVPFNIVLPHGNQLGIDKRGHLTAPDTTVTVSIATMPTHSIKTETQPHGFAVGIPPAVYHPEPTERVVVFDRNLNTDQFSSGAQAPNAQRRTPDSTFSETFKEGVQEVFFPSDLSLRMPGMNSEDY-VFDSVSGNNFEYTLEASKSLRQKPGDSTMTYLNKGQFYPITLKEVSSSEGIHHPISKVRSVIMVVFAEDKSREDQLRHWKYWHSRQHTAKQRCIDIADYKESFNTISNIEEIAYNAISFTWDINDEAKVFISVNCLSTDFSSQKGVKGLPLNIQVDTYSYNNRSNKPVHRAYCQIKVFCDKGAERKIRDEERKQSKRKV-SDVKVPLLPSHKRMDITVFKPFIDLDTQPVLFIPDVHFANLQRGTHVLPIASEELEGEGSVLKRGPYGTEDDFAVPPSTKLARIEEPKRVLLYVRKESEEVFDALMLKTPSLKGLMEAISDKYDVPHDKIGKIFKKCKKGILVNMDDNIVKHYSNEDTFQLQIEEAGGSYKLTLTEI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A286YAF2-1", "uniprot_id": "A0A286YAF2_DANRE", "id": "A0A286YAF2-1", "name": "", "aln": "MSQEHENKRAVLVLPNDPAYNQRRPYTSEDEAWKSFLENPLTAATKAMMSINGDEDSAAALGLLYDYYKVPRDKRTISQQKTDVLGSDVDPNKRNMLTPLQET-SMQLGDNRIQVLKGVPLNIVLP-GNQHVQDKRGLFPSPDTTVTVSIAPVASNSVKTEGPSHGFSVTVP-NPHCAEPDSHTVVFDRQLPHNQFS-----PNTQPRTPDSTFPE----NPDVFSFPGDLQLRMGPITQDDYGTFDTVSGNNFEYILEASKSLRQKSGDGTMTYLNKGQFYPITLRETDNGKLLQGPICKVRSVVMVVFGEEKSRDDQLKHWKYWHSRQHTAKQRCIDIADYKESFNTISNIEEISYNAISFTWDISEEAKIFISVNCLSTDFSSQKGVKGLPLNIQIDTYSYNNRSNKPIHRAYCQIKVFCDKGAERKIRDEERKQSRRKVGADVKVPLL--HKRTDMTVFRTLTDFETQPVLFIPDIHFSTFQR----HAFTAEDSE-EGSAMKRLPY-TEEEFGSPP-NKLARMDEPKRVLLYVRRETEEVFDALMLKTPTLKGLVEAISEKYEVSLEKIGKVYKKCKKGILVNMDDNIIKHYSNEDTFQIQMEEMGGMIKLTLTEIE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:**::***.**** *:. * ***.***********************************************::*: * *.:* .: * .*** :. : * :. *:**:****.**:***** *** **** :.:**********.:.::*:*** .***:* :* : .** .:.*****:* :*** **:* *******.* . : . **.**.*** :..:** .**:******** **********.**.***************:*....: :: **.*****:****.*:***:***:***********************************:**********.:***:*************************:************:***************************:*** :******* *** *:***:.: *::*********:**:.:** .:::*: * ***.:** ** **::*. ** .****::**********:*:************:****:****:**:*. :****::***************:**********:*:** ** ******* ", "identical_positions": 434, "similar_positions": 116, "identity": "69.77%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3667", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35777-1", "uniprot_id": "MAGT1_RAT", "id": "O35777-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1", "aln": "MASPRWLWCVCATAAVTLLLVSKVPS-ASAQRKKEKVLVEKVIQLMEWTNQRPVIRMNGDKFRPLVKAPP--RNYSVIVMFTALQLHRQCVVCKQADEEFQILANFWR------YSSAFTNRIFFAMVDFDEGS----DVFQMLNMNSAPTFINFPPKGKPKRAD-------TYELQVRGFSAEQIARWIADRTDVNIRVIRPPNYAG-PLMLGLLLAVIGGLVYLRRSNMEFLFN--KTGWAFAALCFVLAMTSGQMWNHIRGPPYAHKNPHTGHVNYIHGSSQAQFVAETHIVLLFNGGVTLGMVLLCEAAA---SDMDIGKRRMMCIAGIG------LVVLFFSWMLSIFRSKYHGYPYSFLMS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQY5-1", "uniprot_id": "MAGT1_MOUSE", "id": "Q9CQY5-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1", "aln": "MASPRWFWSVCAIAAVALLLVSKVPS-ASAQRKKEMVLSEKVSQLMEWANKRPVIRMNGDKFRRLVKAPP--RNYSVVVMFTALQLHRQCVVCKQADEEFQILANSWR------YSNAFTNRIFFAMVDFDEGS----DVFQMLNMNSAPTFINFPPKGKPKRAD-------TYELQVRGFSAEQIARWIADRTDVNIRVIRPPNYAG-PLMLGLLLAVIGGLVYLRRSNMEFLFN--KTGWAFAALCFVLAMTSGQMWNHIRGPPYAHKNPHTGHVNYIHGSSQAQFVAETHIVLLFNGGVTLGMVLLCEAAT---SDMDIGKRRMMCIAGIG------LVVLFFSWMLSIFRSKYHGYPYSFLMS-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0U3-1", "uniprot_id": "MAGT1_HUMAN", "id": "Q9H0U3-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1", "aln": "MAARWRFWCVSVTMVVALLIVCDVPS-ASAQRKKEMVLSEKVSQLMEWTNKRPVIRMNGDKFRRLVKAPP--RNYSVIVMFTALQLHRQCVVCKQADEEFQILANSWR------YSSAFTNRIFFAMVDFDEGS----DVFQMLNMNSAPTFINFPAKGKPKRGD-------TYELQVRGFSAEQIARWIADRTDVNIRVIRPPNYAG-PLMLGLLLAVIGGLVYLRRSNMEFLFN--KTGWAFAALCFVLAMTSGQMWNHIRGPPYAHKNPHTGHVNYIHGSSQAQFVAETHIVLLFNGGVTLGMVLLCEAAT---SDMDIGKRKIMCVAGIG------LVVLFFSWMLSIFRSKYHGYPYSFLMS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZV50-1", "uniprot_id": "MAGT1_DANRE", "id": "Q7ZV50-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1", "aln": "--------MLHKLLIVVFLVVCLHDMRLNGQKKKETLLSEKVSQMMEWVSKRAVVRLNGEKFKRLVRAHP--RNYSVIVMFTALQPQRQCGVCRQADEEYQILANSWR------YSSAFTNRIFFAMVDFDEGS----DVFQMLNMNSAPTFINFPAKGKPKRAD-------TYELQVRGFAAEQLARWVADRTDVHIRVIRPPNYAG-PLMLGLLLAFIGSLAYLRRNNLEFLFN--KNVWAFSALCFVLIMTSGQMWNHIRGPPYAHKNPNTGQVSYIHGSSQAQFVAETHIVLLFNAAVTIGMVLLHEAAT---SGLDIVKRKIMCVAGIG------LVVLFFSWLLSVFRAKYHGYPYSFLFG-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48439-1", "uniprot_id": "OST3_YEAST", "id": "P48439-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3", "aln": "---------MNWLFLVSLVFFCGVST------HPALAMSSNRLLKLANKSPKKIIPLKDSSFENILAPPH--ENAYIVALFTATAPEIGCSLCLELESEYDTIVASWFDDHPDAKSSNSDTSIFFTKVNLEDPSKTIPKAFQFFQLNNVPRLFIFKPNSPSILDHSVI----SISTDTGSERMKQIIQAIKQFSQVNDFSLHLPMDWT-PIITSTIITFITVLLFKKQSKLMFSIISSRIIWATLSTFFIICMISAYMFNQIRNTQLAGVGPKGEVMYFLPNEFQHQFAIETQVMVLIYGTLAALVVVLVKGIQFLRSHLYPETKKAYFIDAILASFCALFIYVFFAALTTVFTIKSPAYPFPLLRLSAPFK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q03723-1", "uniprot_id": "OST6_YEAST", "id": "Q03723-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST6", "aln": "-----MKWCSTYIIIWLAIIFHKFQK-------STATASHNIDDILQLKDDTGVITVTADNYPLLSRGVPGYFNILYITMRGTNSNGMSCQLCHDFEKTYHAVADVIR-------SQAPQSLNLFFTVDVNEVP----QLVKDLKLQNVPHLVVYPPAESNKQSQFEWKTSPFYQYSLVPENAENTLQFGDFLAKILNISITVPQAFNVQEFVYYFVACMVVFIFIKKVILPKVTNKWKLFSMILSLGILLPSITGYKFVEMNAIPFIARDAKN-RIMYFSGGSGWQFGIEIFSVSLMYIVMSALSVLLIYVPK---ISCVSEKMRGLLSSFLAC-----VLFYFFSYFISCYLIKNPGYPIVF--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. : : . :: :. ..: : * :.: : * :* : :. :. :. *. . :* *:.:: . . .: ::::..* :. : . . . . :: : :.: : * : ::: : : : :: : : : ::: :. : .:. ..: : :: . ** * : *: :: *:* . : : .: **: : : : * .** : ", "identical_positions": 19, "similar_positions": 101, "identity": "5.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3670", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFY0-1", "uniprot_id": "D3ZFY0_RAT", "id": "D3ZFY0-1", "name": "selenide, water dikinase", "aln": "--------------------MSTRESFNPETYELDKSFRLTRFTELKGTGCKVPQDVLQKLLESLQENHFQEDE--QFLGAVMPRLGIGMDTCVIPLRHGGLSLVQTTDYIYPIVDDPYMMGRIACANVLSDLYAMGVTECDNMLMLLGVSNKMTDRERDKVMPLIIQGFKDAAEEAGTSVTGGQTVLNPWIVLGGVATTVCQPNEFIMPDNAVPGDVLVLTKPLGTQVAVAVHQWLDIPEKWNKIKLVVTQEDVELAYQEAMVNMARLNRTAAGLMHTFNAHAATDITGFGILGHAQNLAKQQRNEVSFVIHNLPVLAKMAAVSKACGNMFGLMHGTCPETSGGLLICLPREQAARFCAEIKSPKYGEGHQAWIIGIVEKGNRTARIIDKPRIIEVAPQVATQNVNPTPGATS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH69-1", "uniprot_id": "SPS1_MOUSE", "id": "Q8BH69-1", "name": "Selenide, water dikinase 1", "aln": "--------------------MSTRESFNPETYELDKSFRLTRFTELKGTGCKVPQDVLQKLLESLQENHFQEDE--QFLGAVMPRLGIGMDTCVIPLRHGGLSLVQTTDYIYPIVDDPYMMGRIACANVLSDLYAMGVTECDNMLMLLGVSNKMTDRERDKVIPLIIQGFKDAAEEAGTSVTGGQTVLNPWIVLGGVATTVCQPNEFIMPDNAVPGDVLVLTKPLGTQVAVAVHQWLDIPEKWNKIKLVVTQEDVELAYQEAMMNMARLNRTAAGLMHTFNAHAATDITGFGILGHAQNLAKQQRNEVSFVIHNLPVLAKMAAVSKACGNMFGLMHGTCPETSGGLLICLPREQAARFCAEIKSPKYGEGHQAWIIGIVEKGNRTARIIDKPRIIEVAPQVATQNVNPTPGATS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49903-1", "uniprot_id": "SPS1_HUMAN", "id": "P49903-1", "name": "Zincore component SEPHS1", "aln": "--------------------MSTRESFNPESYELDKSFRLTRFTELKGTGCKVPQDVLQKLLESLQENHFQEDE--QFLGAVMPRLGIGMDTCVIPLRHGGLSLVQTTDYIYPIVDDPYMMGRIACANVLSDLYAMGVTECDNMLMLLGVSNKMTDRERDKVMPLIIQGFKDAAEEAGTSVTGGQTVLNPWIVLGGVATTVCQPNEFIMPDNAVPGDVLVLTKPLGTQVAVAVHQWLDIPEKWNKIKLVVTQEDVELAYQEAMMNMARLNRTAAGLMHTFNAHAATDITGFGILGHAQNLAKQQRNEVSFVIHNLPVLAKMAAVSKACGNMFGLMHGTCPETSGGLLICLPREQAARFCAEIKSPKYGEGHQAWIIGIVEKGNRTARIIDKPRIIEVAPQVATQNVNPTPGATS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZW38-1", "uniprot_id": "SPS1_DANRE", "id": "Q7ZW38-1", "name": "Selenide, water dikinase 1", "aln": "--------------------MSVRESFNPESYELDKNFRLTRFTELKGTGCKVPQDVLQKLLESLQENHYQEDE--QFLGAVMPRLGIGMDTCVIPLRHGGLSLVQTTDYIYPIVDDPYMMGRIACANVLSDLYAMGVTECDNMLMLLGVSNKLTEKERDKVMPLVIQGFKDASEEAGTSVTGGQTVINPWIVLGGVATTVCQPNEFIMPDNAVPGDVLVLTKPLGTQVAVAVHQWLDIPEKWNKIKLVVTQEDVELAYQEAMLNMARLNRTAAGLMHTFNAHAATDITGFGILGHAQNLARQQRTEVSFVIHNLPVLAKMAAVSKACGNMFGLMHGTCPETSGGLLICLPREQAARFCAEIKSPKYGEGHQAWIIGIVEKGNRTARIIDKPRIIEVAPQVATQNVNTTPGATS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O18373-1", "uniprot_id": "SPS1_DROME", "id": "O18373-1", "name": "Inactive selenide, water dikinase-like protein", "aln": "MSYAADVLNSAHLELHGGGDAELRRPFDPTAHDLDASFRLTRFADLKGRGCKVPQDVLSKLVSALQQDYSAQDQEPQFLNVAIPRIGIGLDCSVIPLRHGGLCLVQTTDFFYPIVDDPYMMGKIACANVLSDLYAMGVTDCDNMLMLLAVSTKMTEKERDVVIPLIMRGFKDSALEAGTTVTGGQSVVNPWCTIGGVASTICQPNEYIVPDNAVVGDVLVLTKPLGTQVAVNAHQWIDQPERWNRIKLVVSEEDVRKAYHRAMNSMARLNRVAARLMHKYNAHGATDITGFGLLGHAQTLAAHQKKDVSFVIHNLPVIAKMAAVAKACGNMFQLLQGHSAETSGGLLICLPREQAAAYCKDIEKQ---EGYQAWIIGIVEKGNKTARIIDKPRVIEVPAKD-------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *..*:* :::** .******::*** *********.**:.:**::: :*: ***...:**:***:* .*********.******::***********:****************:********.**.*:*::*** *:**:::****:: ****:*****:*:*** .:****:*:*****:*:***** **************** .***:* **:**:*****::***. **:.** .******.** ***.:***.********:*****.** :*:.:**********:******:******* *::* ..**************** :* :*:. **:************:*********:***..: ", "identical_positions": 265, "similar_positions": 87, "identity": "64.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3671", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y653-1", "uniprot_id": "AGRG1_HUMAN", "id": "Q9Y653-1", "name": "Adhesion G protein-coupled receptor G1", "aln": "MTPQSLLQTTLFLLSLLFLVQGAHGRGHREDFRFCSQRNQ--THRSSLHYKPTPDLRISIENSEEALTVHAPFPAAHPAS---RSFPDPR-GLYHFCLYWNRHAGRLHLLYGKRDFLLSDKASSLLCFQHQEESLAQGPPLLATSVTSWWSPQNISLPSAASFTFSFHSPPHTAAHNASVDMCELKRDLQLLSQFLKHPQKASRRPSAAPASQQLQSLESKLTSVRFMGDMVSFEEDRINATVWKLQPTAGLQDLHIHSRQEEEQSEIME-YSVLLPRTLFQRTKGRS-----------GEAEKRLLLVDFSSQALFQDKNSSQVLGEKVLGIVVQNTKVANLTEPVVLTFQHQLQPKNVTLQCVFWVEDPTLSSPGHWSSAGCETVR-RETQTSCFCNHLTYFAVLMVSS-VEVDAVHKHYLSLLSYVGCVVSALACLVTIAAYLCSRVPLPCRRKPRDYTIKVHMNLLLAVFLLDTSFLLSEPVALTGS-EAGCRASAIFLHFSLLTCLSWMGLEGYNLYRLVVEVFGTYVPGYLLKLSAMGWGFPIFLVTLVALVDVDNYGPIILAVHRTPEG---VIYPSMCWIR----DSLVSYITNLGLFSLVFLFNMAMLATMVVQILRLRPHTQKWS-----HVLTLLGLSLVLGLPWALIFFSFASGTFQLVVLYLFSIITSFQGFLIFIWYWSMRLQARGGPSPLKSNSDSARLPISSGSTSSSRI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K209-1", "uniprot_id": "AGRG1_MOUSE", "id": "Q8K209-1", "name": "Adhesion G protein-coupled receptor G1", "aln": "MAVQVLRQMVYFLLSLFSLVQGAHSGSPREDFRFCGQRNQ--TQQSTLHYDQSSEPHIFVWNTEETLTIRAPFLAAPDIP---RFFPEPR-GLYHFCLYWSRHTGRLHLRYGKHDYLLSSQASRLLCFQKQEQSLKQGAPLIATSVSSWQIPQNTSLPGAPSFIFSFHNAPHKVSHNASVDMCDLKKELQQLSRYLQHPQKAAKRPTAAFISQQLQSLESKLTSVSFLGDTLSFEEDRVNATVWKLPPTAGLEDLHIHSQKEEEQSEVQA-YSLLLPRAVFQQTRGRR-----------RDDAKRLLVVDFSSQALFQDKNSSQVLGEKVLGIVVQNTKVTNLSDPVVLTFQHQPQPKNVTLQCVFWVEDPASSSTGSWSSAGCETVS-RDTQTSCLCNHLTYFAVLMVSS-TEVEATHKHYLTLLSYVGCVISALACVFTIAAYLCS------RRKSRDYTIKVHMNLLSAVFLLDVSFLLSEPVALTGS-EAACRTSAMFLHFSLLACLSWMGLEGYNLYRLVVEVFGTYVPGYLLKLSIVGWGFPVFLVTLVALVDVNNYGPIILAVRRTPER---VTYPSMCWIR----DSLVSYVTNLGLFSLVFLFNLAMLATMVVQILRLRPHSQNWP-----HVLTLLGLSLVLGLPWALVFFSFASGTFQLVILYLFSIITSFQGFLIFLWYWSMRFQAQGGPSPLKNNSDSAKLPISSGSTSSSRI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3V3Z3-1", "uniprot_id": "AGRG5_MOUSE", "id": "Q3V3Z3-1", "name": "Adhesion G protein-coupled receptor G5", "aln": "--------------------------------------------------------------------------------------MDPH-GALFFYLCL---------------------------------------------------------------------------LAAQVVLVETLSDLLVLMKRLEQPVGRG----LSSRARHIHSLEQKLLNASFGGHNLTLQTNSIQSLVFKLS--CDFPGLSLSSTTLTNVSQVRAPHAMQFPAELTKGACVTS-----------RPAELRLICIYFFTAHLFQDDRNSSLLNNYVLGAQLDHRPVNNLQKPVNISFWHNRSLEGYTVSCVFWKEGASKSSWGAWSPEGCYTEQPSATQVLCHCNHLTYFAVLMQLSGDPVPAELQVPLEYISFVGCSISIVASLLTILLYAQS-------RKQSDSTTRIHMNLNGSVLLLNVTFLLSSQMTLPTMPRPVCKVLAAVLHYALLSSLTWMAIEGFNLYLFLGRVYNAYIRRYLLKLCMLGWGFPALLVLLLLMIKSSVYGPCVTSLSKSQENGTGFQNVSMCWIR----SPMVHSILVMGYGGFTSLFNLVVLAWALWILCRLRAREKALSPWAYRDTAMVLGLTVLLGTTWTLAFFSFG--VFLLPQLFLFTIFNSLYGFFLFLWFCSQKRYSDAEAKAEMEAVSSSQMTH----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q59I63-1", "uniprot_id": "AGRG1_DANRE", "id": "Q59I63-1", "name": "Adhesion G protein-coupled receptor G1", "aln": "MKQNPAKTARMWIIICLLFVLGQATDNDR-DFKMCGKWLHGIAPQNLEYDLKTGCERIEISANESTLSIQGRITAKCTQSSSIQLDSNPHQNQSHFCVFWEPLLDLLIVEVNGKNHTLCK--------------------------------------------------PNGLQGTCCTDLSQGVQDNAHMYGIVNGSVKGDIITGDLKGNYIFDGAHINCKEKFCDEARLKPRGANMIEEVVMRFNAKGRVDLPCAQGTVIEMDEEFTGHNFTVPAPRFVDANTIPSVYIPSSLRSVSRRKSKVVCTYYKNKTLFERGPSKSALLDDIVGLSVENETIRNLIEPVKIRFHHRPFAPDSSGRCVSWDTKQDNEVN--WKDDGCDTVKINEEQTECHCNHLTYFAILVQVE-QKSTVRHLKALTFITAVGCAVSLVSCLVLFYWLCKR------RRGKKNQISLVHRGLVVAIFLLCLFFILTGILANVAN-ETVCQLTGSLLHYGLLSTLCWMAMEVFHTFLLVRKVFNSPLP--IWIFYLMGFGFPFLLVSILLSVG-DIYGERKIKPSDDVNN-----PYRMCWMTEGDKSQLAHYIINIGLLAVVVSSGLVMLFLVVREIRNRPDWKKIHV-----AFLSIWGLTCLYGTTWALGFLDFG--PFSEVTLFLFCIINSLQGFFLMLRYYALERMKKKDVSSSDGSSSGSSKQHMLQTNEKS--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: . .* : . . : : : : :: . :.. . : . :. . : * . .* . : .: : . .* : ::: : . **: ... * : ::* ::: : ** .** : * *. . : ** * . *. ** * *. * ********:*: . . * :: *** :* ::.:. : * : :* .* :::** *:*: :: .. *: . .**:.**: * **.:* :: : :: .*:.: : : : :*:*** :** :: : . ** : ***: . :. : :* ... .:.:* : : . : : **: : * .*:* *:.*. * *:** *:.*: **:::: : : . .. ..: ", "identical_positions": 83, "similar_positions": 152, "identity": "11.43%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3684", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q92629-1", "uniprot_id": "SGCD_HUMAN", "id": "Q92629-1", "name": "Delta-sarcoglycan", "aln": "MPQEQYTHHRSTMPGSVGPQVYKVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTIDGMGNLRITEKGLKLEGDSEFLQPLYAKEIQSRPGNALYFKSARNVTVNILNDQTKVLTQLITGPKAVEAYGKKFEVKTVSGKLLFSADNNEVVVGAERLRVLGAEGTVFPKSIETPNVRADPFKELRLESPTRSLVMEAPKGVEINAEAGNMEATCRTELRLESKDGEIKLDAAKIRLPRLPHGSYTPTGTRQKVFEICVCANGRLFLSQAGAGSTCQINTSVCL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P82347-1", "uniprot_id": "SGCD_MOUSE", "id": "P82347-1", "name": "Delta-sarcoglycan", "aln": "MPQEQYSHHRSTMPSSEGPHIYKVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTIDGMGNLRITEKGLKLEGDSEFLQPLYAKEIKSRPGNALYFKSARNVTVNILNDQTKVLTQLVTGPKAVEAYGKRFEVKTVSGKLLFSADDSEVVVGAERLRVLGAEGTVFPKSIETPNVRADPFKELRLESPTRSLVMEAPKGVEINAEAGNMEAICRSELRLESKDGEIKLDAAKIKLPRLPRGSYTPTGTRQKVFEVCVCANGRLFLSQAGTGSTCQINTSVCL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3AU43-1", "uniprot_id": "A0A8M3AU43_DANRE", "id": "A0A8M3AU43-1", "name": "", "aln": "MTQEQCP-HRNNVQSTEKPQVYKVGIYGWRKRCLYFFVLLLMILIVVNLALTIWILKVMNFTIDGMGHLRITERGLKLEGDSEFLQPLYAKEIQSRPGSPLFLQSSKNVSVNILNEKKQLVSQLVAGSHGVHARGKMLEVKSSSGKLLFSADDHEVVVGAERLRVMGAEGAVFSNSVETPHVRAEPFKELRLESPTRSLYMEAPKGVKIEADAGDFQATCRSDLRLESKDGEISLDASKIKLPRLPEGKASTSGPRQTVFEVCVCPNGKLFLSQAGTGSTCQMSSNLCL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.*** . **..: .: *::************************:****:****************:*****:*******************:****..*:::*::**:*****::.::::**::*.:.*.* ** :***: *********: ***********:****:**.:*:***:***:************** *******:*:*:**:::* **::**********.***:**:*****.*. :.:*.**.***:***.**:*******:*****:.:.:**", "identical_positions": 205, "similar_positions": 72, "identity": "70.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3689", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L225-1", "uniprot_id": "A0ABK0L225_RAT", "id": "A0ABK0L225-1", "name": "DNA/RNA-binding protein KIN17", "aln": "MGKSDFLSPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIEEQVR--RGLEGKE-QETPVFTELSRE-NDEEKVTFNLNKGAGSSAGATTSKSSSLGPSALKMLGSTASVRRKESSQSSAQP-AKKKKKSALDEIMEIEEEKK-RTARTDSWLQPGIIVKIITKKLGEKYHKKKGVVKEVIDRYTAVVKMTDSGDRLKLDQTHLETVIPAPGKRVLVLNGGYRGNEGTLESINEKTFSATIVIETGPLKGRRLEEPRTEPRTLHLLGKRTTAELNPQPKTSIF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K339-1", "uniprot_id": "KIN17_MOUSE", "id": "Q8K339-1", "name": "DNA/RNA-binding protein KIN17", "aln": "MGKSDFLSPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIEEQVR--RGLEGKE-QETPVFTELSRE-NEEEKVTFNLNKGAGGSAGATTSKSSSLGPSALKLLGSAASGKRKESSQSSAQP-AKKKK-SALDEIMELEEEKK-RTARTDAWLQPGIVVKIITKKLGEKYHKKKGVVKEVIDRYTAVVKMTDSGDRLKLDQTHLETVIPAPGKRVLVLNGGYRGNEGTLESINEKAFSATIVIETGPLKGRRVEG----------IQYEDISKLA--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60870-1", "uniprot_id": "KIN17_HUMAN", "id": "O60870-1", "name": "DNA/RNA-binding protein KIN17", "aln": "MGKSDFLTPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIEEQVR--RGLEGKE-QEVPTFTELSRE-NDEEKVTFNLSKGACSSSGATSSKSSTLGPSALKTIGSSASVKRKESSQSSTQSKEKKKKKSALDEIMEIEEEKK-RTARTDYWLQPEIIVKIITKKLGEKYHKKKAIVKEVIDKYTAVVKMIDSGDKLKLDQTHLETVIPAPGKRILVLNGGYRGNEGTLESINEKTFSATIVIETGPLKGRRVEG----------IQYEDISKLA--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N732-1", "uniprot_id": "A0A8M1N732_DANRE", "id": "A0A8M1N732-1", "name": "DNA/RNA-binding protein KIN17", "aln": "MGKADFLTPKAIANRIKAKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPNQFLSYFSDEFKTDFLELLRRRFGTKRVHNNIVYNEYISHREHVHMNATQWETLTDFTKWLGREGFCKVDETPKGWYVQYIDRDPETIRRQEELERKKKQDLDDEERSAKFIEEQVR--RGREGREPTEEPVFTELQRK-SEDEKVAFNLEIAAAGP----SKPSTTLGPSALK---TTASVKRKESSLSGEFK--DKKKKSALDEIIEMEEQKK-KSVRSDNWIQENIVVKVVTKKLGEKYYKKKAIIRELQGKYTAVVKMVDSGDKLKLDQSHVETVIPAPGKRVLILNGQYRGTEAILEGINEHKFSATLTLDSGRMKGKTVEG----------IAYEDFSKLA--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPH4-1", "uniprot_id": "Q9VPH4_DROME", "id": "Q9VPH4-1", "name": "", "aln": "MGRAEVGTPKYLANKMKSKGLQKLRWYCQMCEKQCRDENGFKCHTMSESHQRQLLLFADNPGKFLHSFSKEFSDGYMELLRRRFGTKRTSANKIYQEYIAHKEHIHMNATRWLTLSDYVKWLGRTGQVIADETEKGWFVTYIDRSPEAMERQAKADRKEKMEKDDEERMADFIEQQIKNAKAKDGEEDEGQEKFTELKREENEPLKLDIRLEK--------KFQPDTVLGKSALAKRPAPEAEEKVFKKPKSVAG--DSQTRSVLDEIIKQEESKKERANRKDYWLHKGIVVKFISKSMGEKFFKQKAVVLDVIDRYQGKIKFLETGEKLKVDQAHLETVIPALDKPVMVVNGAYRGSEALLRKLDERRYSVSVEILHGPLKGRIVDN----------VQYEDISKLHGA------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40962-1", "uniprot_id": "RTS2_YEAST", "id": "P40962-1", "name": "Zinc finger protein RTS2", "aln": "--MADYDSAKYWSKQGARRGLQKTRYYCQICQRQCKDANGFQSHNKSPSHLRKISQVTAED---ARRYNIQFEKGFLQLLKQRHGEKWIDANKVYNEYVQDRDHVHMNATMHRSLTQFVRYLGRAGKVDVDMD--------IDDTSENVEG----------------------------------------------------------------------------------------PLLIRIHPSSLSSPSE----------DGMLRSQQEEQ-----------EVIAAELLKRQLNR-------AKRQTEKVYQPEMKSEISGD--------------STLKRVQVTFHGNGRVNKKKKKVPPRKDGIKFR-----------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :.* ::: :**** *:***:*::**:* ***:.* * ** *:: : : :. :* .:::**::*.* * * :*:**: .::*:***** :*:::.::*** * .* ** .* :. . . .. .. * ::. ::.:: * .:.:.:.:.. : * :* :*: : * : : : . : : . .. ", "identical_positions": 52, "similar_positions": 85, "identity": "12.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3695", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AKV2-1", "uniprot_id": "A0A8I6AKV2_RAT", "id": "A0A8I6AKV2-1", "name": "TP53-binding protein 1", "aln": "MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQALEEDA-GSHFSVLSRHLPNLQMHKENPVLDIMSNPEQTVAEQ-GDSNSSFSEHLKEKKASDPVESSHLGTSGPISQVIERLPQPNRTSSALGVTVEAASLAEEEKEEE-LEEEKEEVGVNAPDADPRSLAEDSASSQLGFGVLELSQSQDVEEHTVPYDVKQEHLQLVTTNSGSTQLSDVDANTDGKAIKCEEQSTDAISIIE-PSKDIPVTVQPSKGSHVVEEQNLPLVRSEDLPSSPQVSVAAVETKEQVPAQELLEGGLQVQVSSEPEVSSTQEDLFDQSSKTAS-DGCSTPSREEGGCSPVSTPATTLQLLQLSGQKPLVQESLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQGQRKDEPMDMSVIPE-GGEHFQK-LQDDEAVDIEKPLLPSQPAVSPQASTPVSRSTPVFTPAS-LPIPSQPEFSHDIFIPSPSLEEPSNDVEKGGGLHSSSLTVECSKTSESEPKNFTDDLGLSMTGDSCKLMLSTSECSQSSKMESLGSPRTEEVGENTQVEDTEPSSPVTKSK-LPAESESVLVNPTQDDQVEMSQNVDKAKEDEVEDRGDVDVLAAGCKGREDMVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEEFSGSEVEEVPETPCGSHREESKEEPMESIPLHLSLTETQSEALCLQKEAPKEECPEAMEVETSVISIDSPQKLPVLDQELEHKDPETWEEATSEDSSVVIVDVKEPSPRVDISCEPVEGVGKCSDSQSLEGAAPEEEPCAENRLNTPEEKRVECDGDSKAETTEKNSVTEDSPQPPLPSVR-DEPVRPDQELQQPQVQEKES-PVTLDAKVADDKHLGSEGSCQQLEKAPARASQSFCESSS----------------------------------------GISNYPESTIATSDVMSESMVEINDPLLGNEKGDSESAPEMDGKLSLKMKLVSPETEASEESLQFSLEKPTTAERRNGSTAIAEPVASPQKPMSVFGCIYEAQQEEEAQSGDPPSTPVRTNLLHFPSAQ-EEDREEPDATPQLRQSEQPVKLIGPVKDAAASEDSASSVSQQRASQG------SLSPQEEVMEADLLEGLGANQDRPSKILMERPTQSNIGIQTMDHSLCAPETVSAATQTVKNVCEQGTSTVEQNSGKQDATVQTERGSGEKPASAPVDDTESLHSQGEEEFEMPQPPHGHVLHRHTRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGG--SSGDLGDISSFSSKASSSHHTSSGTSLSAIHSSGSSGRGAGPLKGKTSGTEPADFALPSSRGGPGKLSPRKGISQTGAPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETVVSGPLGIEDTSPSMSPDDKSFTRIMPRVPDSTKRMDASSGALRRSDSPEIPFQAATGSSDGLDSSSSGNSFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLDNLVEGKRKRRSNISSPATPTASSSSSTTPTRKTTESPRASMGVPSGKRKLTTSEEERSPAKRGRKSATVKPGTVGAAELVSPCESGDNTGEPSVLEEPRGPLPLNKTLFLGYAFLLTMATTSDKLASRSKLLDGPTGSSEEEEEFLEIPPFNKQYTECQLRAGAGYILEDFNEAQCNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFQQHPKYKHDYVSH----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70399-1", "uniprot_id": "TP53B_MOUSE", "id": "P70399-1", "name": "TP53-binding protein 1", "aln": "MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEEDA-GSHFSVLSRHLPNLQMHKENPVLDIVSNPEQSAVEQ-GDSNSSFNEHLKEKKASDPVESSHLGTSGSISQVIERLPQPNRTSSALAVTVEAASLPEEEKEEEELEEEKEGVGANAPGADS-LAAEDSASSQLGFGVLELSQSQDVEEHTVPYDVNQEHLQLVTTNSGSSPLSDVDAST---AIKCEEQPTEDIAMIEQPSKDIPVTVQPGKGIHVVEEQNLPLVRSEDRPSSPQVSVAAVETKEQVPARELLEEGPQVQPSSEPEVSSTQEDLFDQSSKTAS-DGCSTPSREEGGCSPVSTPATTLQLLQLSGQKPLVQESLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQGGRKDEPMDMSVIPV-GGEPFQK-LHDDEAMETEKPLLPSQPAVSPQASTPVSRSTPVFTPGS-LPIPSQPEFSHDIFIPSPSLEEPSDDVKKGGGLHSSSLTVECSKTSESEPKNFTDDLGLSMTGDSCKLMLSTSEYSQSSKMESLGSPRTEEDRENTQIDDTEPLSPVSNSK-LPADSENVLVTPSQDDQVEMSQNVDKAKEDETEDRGD-------CKGREDAVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMDTKEHHPEEGFSGSEVEEVPETPCGSHREEPKEEPMESIPLHLSLTETQSEALCLQKEAPKEECPEAMEVETSVISIDSPQKLQVLDQELEHKDPDTWEEATSEDSSVVIVDVKEPSPRADVSCEPLEEVEKCSDSQSWEGVAPEEEPCAENRLDTPEEKRIECDGDSKAETTEKDAVTEDSPQPPLPSVR-DEPVRPDQETQQPQVQEKES-PVTVDAEVADDKQLGPEGACQQLEKAPACASQSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVTSESMVEINDPLLGNEKGDSESAPEMDGKLSLKMKLVSPETEASEESLQFSLEKPTTAERKNGSTAIAEPVASLQKPVPVFGCIYEAQQEKEAQSEAPPSAPDRANLLHFPSAQ-EEDKERPDVTPKLRQSEQPVKPVGPVMDDAAPEDSASPVSQQRASQEQRASQEPFSPAEDVMETDLLEGLAANQDRPSKMLMDRPTQSNIGIQTVDHSLCAPETVSAATQTVKSVCEQGTSTAEQNSGKQDATVQTERGSGEKPASAPVDDTESLHSQGEEEFEMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGG--SSGDLGDISSFSSKASSSHHTSSGTSLSAIHSSGSSGRGAGPLKGKASGTEAADFALPSSRGGPGKLSPRKGISQTGAPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETVVSGPLGVEDISPSMSPDDKSFTRIMPRVPDSTKRTDASSSTLRRSDSPEIPFQAATGSSDGLDSSSSGNSFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLDNLVEGKRKRRSNISSPVTPTAASSSSTTPTRKATESPRASTGVPSGKRKLPTSEEERSPAKRGRKSATVKPGTVGAAEFVSPCETGDNIGEPSVLEEPRGPLPLNKTLFLGYAFLLTMATTSDKLASRSKLLDGPTGSSEEEEEFLEIPPFNKQYTECQLRAGAGYILEDFNEAQCNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12888-1", "uniprot_id": "TP53B_HUMAN", "id": "Q12888-1", "name": "TP53-binding protein 1", "aln": "-----MDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDS-GSHFSMLSRHLPNLQTHKENPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANT---AIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGS-LPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGE-------AMVTDVLE-DQKEGRSTNKENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGG--SSGDLGDISSFSSKASSLHRTSSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKSFSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEEERSPAKRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFLLTMATTSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z753-1", "uniprot_id": "A0A8M6Z753_DANRE", "id": "A0A8M6Z753-1", "name": "TP53-binding protein 1", "aln": "-----MDPGESDLDSSFPQTENPCLIVEDSQPDSVALEDDPDTSYCALLARRLSNLQPTSQSPVLELISSPTKSCCLQTGSQIDKGGNTAHSDNLQNNLGSAATEHS----QVFEVCSLP--------------------------VSKRTVTEHMESEANSTTHCTEAHEEMSQFGLLELSESQGVFEEDDLDGANKKNVQKPTSQYVLKSSERVLSNK--------------------------------------DGNSTGSEVTSSCPLKPQDGESRKLSIQAILHSQLPDS----QEDEEDVLVSSQDDMFEKETNGTKADSSVS------EHLPTSTPAQSLRLLHLSGQGTYVQESLSQQSVDFVAATQDNLSQTPYIVPNSPTEKDQNCNETAESPMDTSAPPEDQPQ-GREEEPMDTDPCPKP-----QPTASTPVSQNSPGFILEKRLSVPSQPEFSHDVFISTPSLEPVNNNQGTEASKRQLPHPNCTSATESTPPKPSSPEEQLNKSSSSFSQPCEAAEDFQLELSSENSCFALKT--QSFIVEEDSQATQIQDQGTVVTDKSNSSPKPHSQNEDKNSTDSEPSKASNSNVPDS------KITSAVPEKAEDLNISQKLNNGGNQIAN-ATPGATLSQLSVSSECVSATPNLPQTSKSTDAGCPQASPLTDKPATPVPVAQHTQSQSVLTASSQKNTGNKEKHDGQNQRLSQPMLHSHSVTTDSVRN----VEEEEQMEEGEIKSTVKGDDTGINLALSQSQALSPEPMEEEEEKGEASIRSSSREESFSVMVLEESQRVSQEKVQ------------KGKSPPFKSSSQPVSGSIQ-DKPEALAKISGSQPVSSTKVSPLRLEKTKSQNTQPSSSG--QQKVNSDNAANKSLSDSSGELPFHFTLPKEGELIRPAVSATPPQISLLKKTP-RHSTPIEMNSFSEPSVG--DVTRETMANSEISVEESREGEEPVAAEQDGKLSLRMKLVTPVEEGSSGPECFSLQKPSLTD-EEGSVSKATAVAMAVTSPSVFSRVREVHRQTQVEDDAESSDPLIRQPSQLLSPTITNDSE-----------------LSPNCPKETSNSSRASVTEAVSLNPG--------ALEADSEALVSGLLSPAREREALDTFDRP-QTPVRKKAVSQQTSVDISSTTSPPSKKAVSQQTSFDLS---GPHNLSGRGEPSTPTRTQPVPS------------------------LRRHVRTIQEVRTTVTRIITDVYYEDGREVNRKVTQESEEPVVDRCVVENDISPSRTGSSMTSGDLADVSSLSSKAP-SHHSSSGTSSGGLGPIRMPDFLMPPSRGAKFGRSLCVFNP---RRGGRQQQPRTLTLVVGSEVTDARGSR-------VSTQLSPRGRARRGRPPSRGGRPGQRGGAHAPGGASSS-----EEEPFAQRHVQMPISPVEPSATS-------------HSESLNTTSPDNSTGSSSFVGLRVLAKWSSNSYFYSGSITRDLGENRFRLLFDDNQECEVQGKDILLCDPIPLETEVTALTEEEYFNIGVVKGHKTQGSEFLYCVEKDGQSSYYSRTSVILSMEQGSRLREQYGLGPYEPSTPQTMACDISLDNLVEGKRRRRGNCSGAGTPTRSSSNSPR-----------NPGPSGKRKLISCTEEERTPPKRGRRGAGARVGRR-IAACNTSGSGVDLPPDPNDLVATHGPLPENSSLFMGFVFLLTASSEGDRYSSHQ--------SSDEDEEYVQRAPYNKHYTVSQLEAGGGMILLDFNEEQCKAAYQSLLIADQHCRTRKYLLCVAGGVPCVSQMWVRDCCQEKKLLNYRNYLLPAGLGPG-GRIVEWHPRSNPFKALKVMLIAEDR---VDLWTSLLSMGGAEKVYRQES-QNISDIPDVKFDVAVTSSACTSEEVKR-VASDMPVVSLEWLIQSLICGKCLNFDSNSEFCHNTST-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P14737-1", "uniprot_id": "RAD9_YEAST", "id": "P14737-1", "name": "DNA repair protein RAD9", "aln": "--------------------------------------------MSGQLVQWKSSPDRVTQSAIKEALHSPLADGDMN--------EMNVPVDPLENKVNS-----------------------------------------------TNIIEGSPKANPNPVKFMNTSEIFQKSLGLLDESPRHDDELNIEVGDNDRPNANILHN-------------------------------------------------------------------------------------------------ERTPDLDRIANFFKSNR----------------------TPGKENLLTKYQ-------------SSDLEDTPLMLRKKMTFQTPTDPLEQKTFKKLKSDTGFCYYGEQNDGEE-----------------------NASLEVTEADATFVQMAERSADNYDCALEGIVTPKRYKDELSKSGGMQDERVQKTQIMISAESPNS--------------------------ISSYDKNKITGNGRTTRNVNKVFNNNEDNIGAIEEKNPVKKKSENYSSDDLRERNNQIIQSNESEEINELEKNLN--------VSGRENDVNNLDIDINSAVSGTPSRNNAEEEMYSSESVNNREPSKKWIFRYSKDKTENNSNRSTQIVNNPRTQEMPLDSISIDTQPLSKSFNTETNNELETQIIVSSLSQGISAQKGPVFHSTGQTEEIKTQIINSPEQNALNATFETPVTLSRINFEPILEVPETSSPSKNTMSKPSNSSPIPKEKDTFNIHEREVETN---------------NVFSNDIQNSSNAATRDDIIIAGSSDFNEQKEITDRIYLQLSGKQISDSGSDETERMSPNELDTKKESTIMSEVELTQELPEVE----------------------------------EQQDLQTSPKKLVVEEETLMEIKKSKGNSLQLHDDNKECNSDKQDGTESLDVALIEHESKGQSSELQKNLMQLFPSESQEIIQNRRTIKRRQKDTIEIG------EEEENRSTKTSPTKHLKRN----------------------------------------SDLDAASIKREPSCSIT---------------------IQTGETGSGKDSKEQSYVFPEGIRTADNSFLSKDDIIFG----NAVWCQYTWNYKFYPGILLEVDTNQDG--------------------------------------CWIYFETGRSLTKDE-DIYYLDIR-IGDAVTFDGNEYVVVGLECR-------------SHDLNIIRCIRGYDTVHLKKKNASGLLGKRTLIKALSSISLDLSEWAKRAKIILEDNEKNKGDAYRYLR--------------------------HPIRGRKSMTNVLSPKKHTDDEK--------------------------------------------------------DINTHTEVYNNEIESSSEKKEIVKKDSRD------ALAEHAGAPSLLFSSGEIRTGNVFDKCIFVLTSLFENREELRQTIESQGGTVIESGFS---------------TLFNFTHPLAKSLVNKGNTDNIRELALKLAWKPHSLFADCRFACLITKRHLRSLKYLETLALG---------------------WPTLHWKFISACIEKKRIVPHLIYQYLLPSGESFRLSLDSP---------------SKGGIIKSNNIFSFYTQFLRGSNLRDQICGVKKMLN-------------------------------DYIVIVWGR------------SELDSFVKFAFACLSAGRMLTIDLPNIDVDDTEPLLNALDSLVPR------------IGSELSNRKLKFLIYANEN-------------NGKSQMKLLERLRSQISLKFKKFNYIFHTE------------------SKEWLIQTIIN-EDTGFHDDITDNDIYNTISEVR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : .. : .:..: : : .* : . : : * . . : :*:*: * :. . .: : : . . . ::*... **. * : . * *: .. . .: .*..* *: . : . : : ** ::. . * . . ..:. .. : ... . . : : . . . . :. :: . : .. : .... : : : . : : .: : . . .::: *. . .. . * *. . * . . : . .. *: : . : : . .: : . . . : : : : : . . : : : : *.. : .. :.* . : . : . :: .. . : :. :. .: :. :.. .: : :. * . .: .... : . *.. .* : *: :... .* : : .: . : ..: : .: : . . : : . . . . ::. :: . . . : * * : . * : . *. :*: *:** * : ** : :* :* . * ** : .: . . :....:. . . . . : . * * : * . .*.: : . .* .:: * * : ::.. * : .: :* .* *:: .: : * : :. . : .*. : .: *: : .. : *. . .* : .* : *: :: * : . : : : *:: : * :. :* : ...:* :. :* :. *: .. . . *: :.. :: .. .: : *::.* . .: * . : * * : *:* . . : **.:: :::. .* .: . .: *: . * **:** :* : .*... . : ", "identical_positions": 90, "similar_positions": 382, "identity": "4.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-37", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVC0-1", "uniprot_id": "SEPT7_RAT", "id": "Q9WVC0-1", "name": "Septin-7", "aln": "---------------------------------MSVSARSAAAEERSVNCSTM------------------------------------------------------------AQPKNLEGYVGFANLPNQVYR--KSVKRGFEFTLMVVGESGLGKSTLINSLFLT-DLY---------------------SPEYPGPSHRIKKTVQVEQSKVLIK------EGGVQLLLTIVDTPGFGDAVDNS-NCWQPVIDYIDSKFEDYLNAESRVNR-RQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQGHKIKIYEFPET----------------DDEEENKLVKKIKDRLPLAVVGSNTIIE-VNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEEEKANWEAQQRILEQQNSSRTLEKN-----------KKKGKIF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55131-1", "uniprot_id": "SEPT7_MOUSE", "id": "O55131-1", "name": "Septin-7", "aln": "---------------------------------MSVSARSAAAEERSVNCGTM------------------------------------------------------------AQPKNLEGYVGFANLPNQVYR--KSVKRGFEFTLMVVGESGLGKSTLINSLFLT-DLY---------------------SPEYPGPSHRIKKTVQVEQSKVLIK------EGGVQLLLTIVDTPGFGDAVDNS-NCWQPVIDYIDSKFEDYLNAESRVNR-RQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPET----------------DDEEENKLVKKIKDRLPLAVVGSNTIIE-VNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEEEKANWEAQQRILEQQNSSRTLEKN-----------KKKGKIF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16181-1", "uniprot_id": "SEPT7_HUMAN", "id": "Q16181-1", "name": "Septin-7", "aln": "---------------------------------MSVSARSAAAEERSVNSSTMV-----------------------------------------------------------AQQKNLEGYVGFANLPNQVYR--KSVKRGFEFTLMVVGESGLGKSTLINSLFLT-DLY---------------------SPEYPGPSHRIKKTVQVEQSKVLIK------EGGVQLLLTIVDTPGFGDAVDNS-NCWQPVIDYIDSKFEDYLNAESRVNR-RQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPET----------------DDEEENKLVKKIKDRLPLAVVGSNTIIE-VNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQQNSSRTLEKN-----------KKKGKIF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NZC4-1", "uniprot_id": "A0A8M1NZC4_DANRE", "id": "A0A8M1NZC4-1", "name": "Septin", "aln": "-----------------------------------------------------------------------------------------------------------------MAQKNLEGYVGFASLPNQVYR--KSVKRGFEFTLMVVGESGLGKSTLINSLFLT-DLY---------------------SGEYPGPSNRIKKTVQVEQSKVLMK------EGGVQLLLSIVDTPGFGDAVDNS-NCWQPVIDHIDSKFEDYLNAESRVNR-RQMPDSRVHCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMREILEHKIKIYEFPET----------------DDEEENKIVKTIKDRLPLAVVGSNTIIE-ANGKKVRGRQYPWGVAEVENGDHCDFTLLRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTCNGIDNNKAKGQLTKSPLAQMEEERREHVTKMKKMEMEMEQVFEMKVKEKVQKLKDSEGELQRRHEQMKKNLEAQHKELEERRRQFEEERSTWETQQRILEQQK--MTLEKN-----------KKKGKIF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40797-1", "uniprot_id": "PNUT_DROME", "id": "P40797-1", "name": "Protein peanut", "aln": "MNSPRSNAVNGGSGGAISALPSTLAQLALRDKQQAASASASSATNGSSGSESLVGVGGRPPNQPPSVPVAASGKLDTSGGGASNGDSNKLTHDLQEKEHQQAQKPQKPPLPVRQKPMEIAGYVGFANLPNQVYR--KAVKRGFEFTLMVVGASGLGKSTLINSMFLS-DIYN--------------------AEQYPGPSLRKKKTVAVEATKVMLK------ENGVNLTLTVVDTPGFGDAVDNS-NCWVPILEYVDSKYEEYLTAESRVYR-KTISDSRVHCCLYFIAPSGHGLLPLDIACMQSLSDKVNLVPVIAKADTMTPDEVHLFKKQILNEIAQHKIKIYDFPATLE--------------DAAEEAKTTQNLRSRVPFAVVGANTIIE-QDGKKVRGRRYPWGLVEVENLTHCDFIALRNMVIRTHLQDLKDVTNNVHYENYRCRKLSEL---GLVDGKAR-LSNKNPLTQMEEEKREHEQKMKKMEAEMEQVFDMKVKEKMQKLRDSELELARRHEERKKALELQIRELEEKRREFEREKKEWEDVNHVTLEELKRRSLGANSSTDNVDGKKEKKKKGLF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32457-1", "uniprot_id": "CDC3_YEAST", "id": "P32457-1", "name": "Cell division control protein 3", "aln": "MSLKEEQVSIKQDPEQEERQHDQFNDVQIKQESQDHDGVDSQYTNGTQNDDSERFEAAESDVKVEPGLGMG-----------------------ITSSQSEKGQVLPDQPEIKFIRRQINGYVGFANLPKQWHR--RSIKNGFSFNLLCVGPDGIGKTTLMKTLFNNDDIEANLVKDYEEELANDQEEEEGQGEGHENQSQEQRHKVKIKSYESVIE------ENGVKLNLNVIDTEGFGDFLNNDQKSWDPIIKEIDSRFDQYLDAENKINR-HSINDKRIHACLYFIEPTGHYLKPLDLKFMQSVYEKCNLIPVIAKSDILTDEEILSFKKTIMNQLIQSNIELFKPPIYSN--------------DDAENSHLSERLFSSLPYAVIGSNDIVENYSGNQVRGRSYPWGVIEVDNDNHSDFNLLKNLLIKQFMEELKERTSKILYENYRSSKLAKLG----IKQDNSVFKEFDPISKQQEEKTLHEAKLAKLEIEMKTVFQQKVSEKEKKLQKSETELFARHKEMKEKLTKQLKALEDKKKQLELSIN--------SASPNVNHSPVPT-----------KKKGFLR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q04921-1", "uniprot_id": "SPR28_YEAST", "id": "Q04921-1", "name": "Sporulation-regulated protein 28", "aln": "-----------------------------------------------------------------------------------------------------------------MFPMKDHSALEQHTLSRDELRRRKGYKKGLQLSILLLGEKGSGKSTFLNNLCGQ-DISLSDGDYDDDDDKVTNNVTPENGNAIEDIDPGYKTAHLSPGLKLVTRRVYLNDELGVPITLDIILFPGCGDNVDNS-QSSVVIKNYLDQQFANVLKEEVRIKRNTKETDGRPHVCLYFLKSTPRGVKKFDIELMKTICDKVNLIPIIPKADGLTETELNLHKDIVRQEISQNNIRVFDFKSDTLGETLALYDMDIDSSSAKSKYDNDTKIKEISPFAIVCSKTFNKNSENRVEHIRTYEWGSLVVEDQNTSDFIYLKAILLGSHLQELKDVTNNVLYENYRAKVLTEK----------KNNYDIPNYSYIDETSR-------------------GSVSNVSTRRNSASRTLGNPDTNDENAYQIHKEIDEKNRIIEDYQRKIDLLEKMLAAPHQNKV----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : .*..: * :. *.*:.:.:: :* .* **:*:::.: *: . . . : : : . * ** : * :: * ** ::*. :. : . :*.:: : * * :: * * * : ****: .: : : :*: *: : :* *::*:*.*:* :* * .*. : .:: :*.::. . .: . : . * *:: :: : : ... : * * ** *:: .** *: ::: .:::**: *.:: *****. *: : :* .: .. :.* . . . .: : ::::.: :* ", "identical_positions": 62, "similar_positions": 131, "identity": "10.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-371", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61480-1", "uniprot_id": "WDR12_RAT", "id": "P61480-1", "name": "Ribosome biogenesis protein WDR12", "aln": "------MAQLQARFYTENKK--YAVDDVPFSIPATSEVADLSNIINKLLETKNELHKHVEFDFLIKGQFLRMPLVKHMELEDISSEEVVELEYVEKYTAPQPEQCMFHDDWISSIKG--AEEWILSGSYDKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLTASMDQTILLWEWN-------------------IERNKVKALHCCRGHAGSVDAIAVDSSGTKFCSGSWDKMLKIWSTVP------------TDEEDEIQEPTNRPRKKQKTEQLGLTRTPLVTLSGHTEAISSVLWSDADEVC--SASWDHTVRVWDVESGGLKSTLTGNKVFNCISYSPLCKRLASGSTDRHIRLWDPRT-KDGSLVSLSLTSHTGWVTSVKWSPTHDQQLISGSLDNMVKLWDTRSCKAPLYDLAAH--------EDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJA4-1", "uniprot_id": "WDR12_MOUSE", "id": "Q9JJA4-1", "name": "Ribosome biogenesis protein WDR12", "aln": "------MAQLQARFYSENKK--YAVDDVPFSIPAAAEVADLSNIINKLLETKNELHKHVEFDFLIKGQFLRVPLVKHMELENISSEEVVELEYVEKYTAPQPEQCMFHDDWISSIEG--AEEWILSGSYDKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLTASMDQTVLLWEWN-------------------VEKNKVKALHCCRGHAGSVDAIAVDSSGAKFCSGSWDKMLKIWSTVP------------TDEEDEMEEATNRPRKKQKTEQLGLTRTPLVTLSGHTEAISSVLWSDAEEIC--SASWDHTIRVWDVESGGLKSTLTGNKVFNCISYSPLCKRLASGSTDRHIRLWDPRT-KDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLWDTRSCKAPLYDLAAH--------EDKVLSVDWTDTGLLLSGGADNKLYSYSYSPTTSHVGA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZL7-1", "uniprot_id": "WDR12_HUMAN", "id": "Q9GZL7-1", "name": "Ribosome biogenesis protein WDR12", "aln": "------MAQLQTRFYTDNKK--YAVDDVPFSIPAASEIADLSNIINKLLKDKNEFHKHVEFDFLIKGQFLRMPLDKHMEMENISSEEVVEIEYVEKYTAPQPEQCMFHDDWISSIKG--AEEWILTGSYDKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWN-------------------VERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVP------------TDEEDEMEESTNRPRKKQKTEQLGLTRTPIVTLSGHMEAVSSVLWSDAEEIC--SASWDHTIRVWDVESGSLKSTLTGNKVFNCISYSPLCKRLASGSTDRHIRLWDPRT-KDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLWDTRSCKAPLYDLAAH--------EDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NX08-1", "uniprot_id": "WDR12_DANRE", "id": "Q6NX08-1", "name": "Ribosome biogenesis protein wdr12", "aln": "------MSQLQARFFTENKK--YLVDDVPFSIPASSEVADLSGVINKLLEAKNAGHKHVEFDFLVRGQFLRTSLDKHIETENISTEEVVEIEYVEKFTAPQPEECIMHDDWISSVEA--DSEWILTGSYDKTARIWSMEGKAVMTVAGHADVVKDVAWVKRDGLNSVLLTASLDQTVMLWEWN-------------------SERNKVKARHCCRGHAGSVDTIAVDPTRTKFCSGSWDKMLKIWSAVP------------TEEEDEIEEP-NRPRKKQKTEQMGLTRTPLMTLSGHNEAVSSVLWMDADELC--SASWDHTIRLWDAETGGQKSTLSGSKVFNCISYSPLCRRLASGSTDRHVRLWDPRS-KDGSLVLLSLTSHNGWVTAVRWAPSHEHQLVSGSLDNVVKLWDTRSCKAPLYDLAAH--------EDKVLCADWTENGLILSGGADNKLYTYRYAACVSDAGA--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKQ3-1", "uniprot_id": "WDR12_DROME", "id": "Q9VKQ3-1", "name": "Ribosome biogenesis protein WDR12 homolog", "aln": "MDVDNGEGQVQVHLKTKQEH--YAVPDVPYAIDGTVTTVELNTFVNALLRQKD-GSSDTDFDFLVFDEYLRGRLCDHLREKAISFEDAIEIEYVERFPAPEPQDCLLHDDWVSAVKA--RGKWILSGCYDNTLNLWTNKGKHILTISGHTAPIKAVDWISLDEETGRFVSTSQDQTAMLWQWN-------------------VGSNSVECVSVCKGHERGVDSVSVSPDGLRFATGSWDTMLKVWS---------------AELDDAVEGSSKRMKESG-------VRTPKITLQGHRESVSAVQWMDATTLL--TGSWDHTLKVWDLSLEGIKTEISTNKSIFDASYSKLNRLILTASADKNLRLYDPRT-NQGSVVRNTYLGHNAWVQTVMWSTTEEFLFVSGAYDNQNKLWDCRSPKAPLYDLLGH--------GEKVLDIDWSNPKYIVSGGVDNTVRVFKSRKALAEEAETK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12024-1", "uniprot_id": "YTM1_YEAST", "id": "Q12024-1", "name": "Ribosome biogenesis protein YTM1", "aln": "--MTEDKSQVKIRFFTREKDELLHVQDTPMYAPISLKRYGLSEIVNHLLGSEK----PVPFDFLIEGELLRTSLHDYLTKKGLSSEASLNVEYTRAILPPSYLNSFSNEDWVSSLDVGDGSKHIISGSYDGIVRTWDLSGNVQKQYSGHSGPIRAVKYIS----NTRLVSAGNDRTLRLWKTKNDDLKLTSQQQAQEDDDDEVNIEDGKTLAILEGHKAPVVSIDVS-DNSRILSASYDNSIGFWSTIYKEMTVVDPLEDINNPNNKISTAARKRRKLTMKDGTIRRRAPLSLLESHTAPVEQVIFDSTDNTVGYSVSQDHTIKTWDLVTARCIDTRTTSYSLLSIAQLSTLNLLACGSSARHITLHDPRVGASSKVTQQQLIGHKNFVSSLDTCPENEYILCSGSHDGTVKVWDVRS-TSPMYTITREDKSVQKGVNDKVFAVKWAEKVGIISAGQDKKIQINKGDNIFKN-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*:: :: : ::. * *.* : *. .:* ** :. . ****: .: ** * .:: : :* * :::**.. .*. :.: ::**:*::. : *::*.** . * .*: **: :: * ::. . ::::. *:* **: : :. : .** * :: *. :: :.*:*. : .** : :: :. . .: :: *:* *..* .:. * : .: : * ***:: ** : . : : . : .*: ::: * *** ...:. .*. :* :: .. .: : **: *. *:** ** .:*:* : . :**: .*:: ::*.* *:.: . ", "identical_positions": 78, "similar_positions": 146, "identity": "16.35%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3715", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BN56-1", "uniprot_id": "RT31_RAT", "id": "B0BN56-1", "name": "Small ribosomal subunit protein mS31", "aln": "-------MLHRIPAFIRPRPFSGLP-----------------LSCGNREVSVAASVLPAAGSGAVR---------TENTIQRHFCTSRSICSKKDD---------QSVPANETSQKAAESQGEGKE-TLKKNLLDVIKDMKVQLNTAN-VKTTKPR---GRQPPAHLETAVGRLQKALGEPPRKRNEFLSPELVAAASAVADSLPFDKQTTKSELLKQLQQHEEESRAQTDRQKRRVSFTQIISNMKIAKSPSMRVSSRPQHQIQFDEE-----VDSSLSQEKPADFRRRKCLFKGKRLSIFDVKAFDDEAPEPEAAPSLWEIEFAKQLATVSEQPFGNGFEEMIQWTKEGKLWEFPVNNEAGLDDDGSE-FHEHIFLEKHLEDFP-KQGPIRLFMELVTCGLSKNPYLSVRQKVEHIEWFRNYFNEKRDILKENNIHLTS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61733-1", "uniprot_id": "RT31_MOUSE", "id": "Q61733-1", "name": "Small ribosomal subunit protein mS31", "aln": "-------MLHRIPAFLRPRPFSGLP-----------------LSCGNRDVSVA--VLPAAQSGAVR---------TENNIQRHFCTSRSICSKKVD---------QSVPANEISQKAAESQGRGKE-TLKKDLLDIIKDMKVDLSTAN-VKTPKPR---GRKPSASLEATVDRLQKAPEDPPKKRNEFLSPELVAAASAVADSLPFDKQTTKSELLRQLQQHEEELRAQKDREKRRISFTHIISNMKIAKSPSGRASTRPQHQIQFDED-----MDSSLKQEKPTDFRKRKYLFKGKRLSIFADKAFADEPPEPEASPSLWEIEFAKQLASVADQPFENGFEEMIQWTKEGKLWEFPVNNEAGLDDDGSE-FHEHIFLDKYLEDFP-KQGPIRLFMELVTCGLSKNPYLSVKQKVEHIEWFRNYFNEKRDILKENNIAFT------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92665-1", "uniprot_id": "RT31_HUMAN", "id": "Q92665-1", "name": "Small ribosomal subunit protein mS31", "aln": "-------MFPRVSTFLPLRPLSRHP-----------------LSSGSPETSAAAIMLLTVRHGTVRYRSSALLARTKNNIQRYFGTNSVICSKKDK---------QSVRTEETSKETSESQDSEKE-NTKKDLLGIIKGMKVELSTVN-VRTTKPP---KRRPLKSLEATLGRLRRATEYAPKKRIEPLSPELVAAASAVADSLPFDKQTTKSELLSQLQQHEEESRAQRDAKRPKISFSNIISDMKVARSATARVRSRPELRIQFDEG-----YDNYPGQEKTDDLKKRKNIFTGKRLNIFDMMAVTKEAPETDTSPSLWDVEFAKQLATVNEQPLQNGFEELIQWTKEGKLWEFPINNEAGFDDDGSE-FHEHIFLEKHLESFP-KQGPIRHFMELVTCGLSKNPYLSVKQKVEHIEWFRNYFNEKKDILKESNIQFN------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BEP0-1", "uniprot_id": "A2BEP0_DANRE", "id": "A2BEP0-1", "name": "Small ribosomal subunit protein mS31", "aln": "MYRRLLINIHQVRNGLIHAQKTRTPSVKCKENEGFAHTFWTTGSTSHRPLGTSSICFSDNKESSTSLSDDKEKRREENEAKAEVGTDGQRNTEIKKGPDISNTALTSELETEVELKPKEIKKPEKEKTGKESLLELLGAMKVDVTTVRKVRPPRFPRISEKPSTDQMESTQSMFQDAMAEGSKQR-ETLNPALVAAASAAASTLP-NSQQVESELLQQLRKHEAEPDAQRADRQ---NIGDIIADMKVGKRQMGRSNSRPSNQIRFDDDGQGYTEDRSITSELMNGIHRRKNSFTGKRLNIFSP-GMEQESSE--MGPTLWDIDLANQIVQSTNQMPRNGFEEMMQWTKEGKLWQYPINNEAGLDEEASVPFHEHVFLEKHLESFP-RQGPVRHFMELVITGLSKNHHLTVQQKQEHIAWFRDYFQQKDDVMKEAQA---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUX1-1", "uniprot_id": "Q9VUX1_DROME", "id": "Q9VUX1-1", "name": "Small ribosomal subunit protein mS31", "aln": "--------MLAVRSSQRLGLRSLLP-----------------SAFKNVGLVNYSSSQSKNDDGYSS-------SDDEKPTKKKEEPVETAAQRLNR--------LLGTMQATDQLSASDFPRPGDANRKRREAQKQEAAAKNVLTAAKNIASMLGT-----SESDKKQTESELLAKLLGHGSESSSAATGENQTADVSGSP---SGDKELNLSDIIVGMKIDRRQQPQQVEQTRGEYVRRSLASRFKPQNRDGAYQRSQRQ------------------TKREAESFTGSVNLYGGEPLGIFKD----TQLPISNDILSTWSQLSERELSLQASHPPANYFEQMVLWTDQKKVWRFPINNEQDWEDEHNVDFSEHIFLEQHLEDWCPSKGPIRHFMELVCVGLSKNPYLTAQEKKDHIFWFRDYFQAKKDILRDLISKEPSKSISA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * : . :: : . . . . .. : . :.. * :.:.. : . :: : ... . .* .*. . . :.: *::: :: .. : * : : : :* . :: . .. .: : *: *.** : . : *. .:: .: * **::: **.: *:*.:*:*** . ::: . * **:**:::**.: :**:* ***** ***** :*:.::* :** ***:**: * *:::: ", "identical_positions": 54, "similar_positions": 107, "identity": "12.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3724", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZSI9-1", "uniprot_id": "A0A8I5ZSI9_RAT", "id": "A0A8I5ZSI9-1", "name": "Kinesin-like protein", "aln": "--------------------------------------------MSWAELLFGEGTLAAFWRSRDKDEPEVETGITTQQNKPAR----HPEEVAEPR---------------AMVPSRRTWNLGATPSLRGLWRVGRVQEPK---------PGMAR--PAPASPAARPFPHTGQGRLRTGRGKDTLPGGEEDSTSRSAARPSLAQCRALSVDWPGPRSPHRLYLTVQQALQDKGCESKSQGTKEDRLPKRQAPAPRRDREAPEAGGTMNVEKPGGRLLGIGRCSSLSGSPGPDPVVHRTVEAMSQLQEELVVLRERLALHDSDRQATTTQLQNQVENLKEKLISQAQEVSRLRSELGGTDVEKHRDRLMVENEQLRQELRR-------CEAELQELRAQPVVPCQGCEHSQESTQLRDRLSQLQLEVAENKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLKAQSPPVKYVIKTVEVESSKTKQALSESQTRNQHLQEQVAMQRQVLKEMEQQLQNSHQLTIQLR-----------------------------AQIAMYEAELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDPDDDSIIHLLHKGKPVSFELDKVFSPWASQQDVFQEVQALITSCIDGFNVCIFAYGQTGAGKTYTMEGTPENPGINQRALQLLFSEVQEKASDWQYNITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGYNNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGNRLREAQHINRSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGS----RRTELGSWSSQ-----EHLEWEPACQTPQPTARAHSAPG--SGTSSRPGSIRRKLQPSGKLRPVPV------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35231-1", "uniprot_id": "KIFC3_MOUSE", "id": "O35231-1", "name": "Kinesin-like protein KIFC3", "aln": "-----------------------------------------------------------------------------------------------------------------MVPSRRTWNLGATPSLRGLWRVGRVQEPK---------PGMAR--PAPASPAARPFPHTGQGRLRTGRGKDILPSGEEDSTSRTAARPSLAQCRALSVDWPGPRSPHRLYLTVQ-----------------------------------------------------------------------------------------------------------VENLKEKLISQAQEVSRLRSELGGTDAEKHRDRLMVENEQLRQELRR-------CEVELQELRAQPVVPCEGCEHSQESSQLRDKLSQLQLEVAENKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQTRNQHLQEQVAMQRQVLKEMEQQLQNSHQLTVQLR-----------------------------AQIAMYEAELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDPDDDSIIHLLHKGKPVSFELDKVFSPWASQQDVFQEVQALITSCIDGFNVCIFAYGQTGAGKTYTMEGTPENPGINQRALQLLFSEVQEKASDWQYNITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGYNNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGNRLREAQHINRSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLRFAERVRSVELGPGS----RRTELGSWSSQ-----EHLEWEPACQTPQPTARAHSAPG--SGTSSRPGSIRRKLQPSA-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BVG8-3", "uniprot_id": "KIFC3_HUMAN", "id": "Q9BVG8-3", "name": "Kinesin-like protein KIFC3", "aln": "-----------------------------------------------------------------------------------------------------------------MVPSRRTWNLGATPSLRGLWRVGRAPEPE---------PGMARPAPAPASPAARPFPHTGPGRLRTGRGKDTPVCGDEDSSARSAARPALAQCRALSVDWAGPGSPHGLYLTLQ-----------------------------------------------------------------------------------------------------------VEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRR-------CEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLR-----------------------------AQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGL----RRAELGSWSSQ-----EHLEWEPACQTPQPSARAHSAPS--SGTSSRPGSIRRKLQPSGKSRPLPV------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T591-1", "uniprot_id": "A0AB32T591_DANRE", "id": "A0AB32T591-1", "name": "Kinesin-like protein KIFC3", "aln": "MYVLCTLVLLSLHNLFRRPRVLDPVEPKAIESPEKHKPDVGKHGRKKRNKHHIPGSSGPLETSRVHGQSDVDRCLDGFSSRASKRRSVHQDNVLERRKIAQPVQRCGLLGPAVMYGTRKTWDVGHTPCLQELWNKDISLDASSLDILMSDGEEENSFLSLPNSVLQRHCLTSDLSETGTSEQQQLLIQRVTLSCSWTSAYTLQERVCEFQARLRSEDAAKRLLLQRLQTHDHQLNQDNHQNQEYSPLYQEPQEQLRLQAG------------------QLNQAASPTGVRSSTALTQRPVDFPSALQVSKVHSPERLQKVEGEQLAVITGLRTQVKELEEKLVDQTQEVERLRSELGATDLEKQLEVLESENQRLKQELKTSHTQTSCSAARCPHSQDVEVLRGELCRKDEQWRERERRLAALEMQLQDRSAVVEELQQQLEEAAQRRHELQEQLEEASGHRSLNDEQLNTRLCDDEDTLR-RHTTVPQVKYVTKTVEVESAQCKQALMEAQARNTALQEQLSVQRQLLRELEQQLHDSQRTSSQLRQQLRTDRARLYGLLSKAVGGGNTEVTLRLSKILMYEGEMERAQGQLEAEMQSLEEEKNRVIEEAFIRAESEMKAVHENLAGVRMNLLTLQPALRTLTCDYNCLKRQVQDFPYMLEKAIAEAKQEICQVIGEVSSANQELLRKYKREMNLRKKCHNELVRLKGNIRVLCRVRPVCAGEADAADTKNLVTFDPEDDAVLYLSNKGKLMTFELDKVFTTQATQEEVFQEVQSLVTSCIDGFNVCIFAYGQTGSGKTYTMEGIPEDPGINQRALRLLFSEVSEKKPDWDYKITVSMVEIYNETLRNLLGDNPNEKLDIKMCPDGSGQLYVPGLSEFTVESVEDINKVFDLGHMNRATACTNLNEHSSRSHALLIITVAGFNSSTGHRTSGKLNLVDLAGSERIAKSGAEGSRLREAQCINKSLSALGDVINSLRSKHSHVPFRNSRLTYLLQDSLSGDSKTLMMVQVSPLESNISESVCSLKFAQRVRTVEIGPSSSSSRRQAENSSTSSSPTHDSVELDSPPVTPVPLPISRASSAGSTLSSTSKTPTTRRRSHSQLSTDRQVDRGSPLVGDGGQDE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :*:**::* **.*: **. . :.. . * * * :. .. *.. :: * : ::* . : :.. . :.: * * *:.*:***:.*:***.*******.** **: : * **::*:**:: . .. . : . *.:.:: : . :*: *:::: : ..::.**: :::: ::* *:: :*::. ..:: ::*:*. ** *..:*: :: * **** *******:: **** *:*:** ****:::***:*:*:****:.*:: : :** ::* ***.*:***:**: *******:***.***** **: ************* ************* *** *****:.** :*::*: ..* ** *.* **.* ********:**::******************:.***** :.:..::.* ****.:**::::* :*** ::*******:. *:*::******:*:******************:******** .*:********:******.** .**:*.**** .*****.**:***.:*:***:*::*************:** *:**:******::*: **:* ***************:** *.:.*** **:*************:.******.****** **:********* :***::.*******:*****************:*****:*.* **:: **:**:***:**:**. *::* .* **. .*: *. .* * :** ** . *.**. * : **. . . ", "identical_positions": 445, "similar_positions": 227, "identity": "39.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3725", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q01954-1", "uniprot_id": "BNC1_HUMAN", "id": "Q01954-1", "name": "Zinc finger protein basonuclin-1", "aln": "MRRRPPSRGGRGAARARETRRQPRHRSGRRMAEAISCTLN-CSCQSFKPGKINHRQCDQCKHGWVAHALSKLRIPPMYPTSQVEIVQSNVVFDISSLMLYGTQAIPVRLKILLDRLFSVLKQDEVLQILHALDWTLQDYIRGYVLQDASGKVLDHWSIMTSEEEVATLQQFLRFGETKSIVELMAIQEKEEQSIIIPPSTANVDIRAFIESCSHRSSSLPTPVDKGNPSSIHPFENLISNMTFMLPFQFFNPLPPALIGS-LPEQYMLEQGHDQSQDPKQEVHGPFPDSSFLTSSSTPFQVEKDQCLNCPDAITKKED---STHLSDSSSYNIVTKFERTQLSPEAKVKPERNSLGTKKGRVFCTACEKTFYDKGTLKIHYNAVHLKIKHKCTIEGCNMVFSSLRSRNRHSANPNPRLHMPMNRNNRDKDLRNSLN--LASSENYKCPGFTVTSPDCRPPPSYPGSGEDSKGQPAFPNIGQNGVLFPNLKTVQPVLPFYRSPATPAEVANTPGILPSLPLLSSSIPEQLISNEMPFDALPKKKSRKSSMPIKIEKEAVEIANEKRHNLSSDEDMPLQVVSEDEQEACSPQSHRVSEEQHVQSGGLGKPFPEGERPCHRESVIESSGAISQTPEQATHNSERETEQTPAL-IMVPREVEDGGHEHYFTPGMEPQVPFSDYMELQQRLLAGGLFSALSNRGMAFPCLEDSKELEHVGQHALARQIEENRFQCDICKKTFKNACSVKIHHKNMHVKEMHTCTVEGCNATFPSRRSRDRHSSNLNLHQKALSQEALESSEDHFRAAYLLKDVAKEAYQDVAFTQQASQTSVIFKGTSRMGSLVYPITQVHSASLESYNSGPLSEGTILDLSTTSSMKSESSSHSSWDSDGVSEEGTVLMEDSDGNCEGSSLVPGEDEYPICVLMEKADQSLASLPSGLPITCHLCQKTYSNKGTFRAHYKTVHLRQLHKCKVPGCNTMFSSVRSRNRHSQNPNLHKSLASSPSHLQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35914-1", "uniprot_id": "BNC1_MOUSE", "id": "O35914-1", "name": "Zinc finger protein basonuclin-1", "aln": "------------------------------MAEAIGCTLN-CSCQCFKPGKINHRQCEQCRHGWVAHALSKLRIPPVYPTSQVEIVQSNVVFDISSLMLYGTQAIPVRLKILLDRLFSVLKQDEVLQILHALDWTLQDYIRGYVLQDASGKVLDHWSIMTSEEEVATLQQFLRFGETKSIVELMAIQEKEEQSVIVPPTTANVDIRAFIESCGHRSASLPTPVDKGSPGGMHPFENLISNMTFMLPFQFFNPLPPALIGS-LPEQYMLEQGQDQSQEPKQELHGPFSDSSFLTS--TPFQVEKEQCLNCPETVPQKED---SAHLSDSSSYSIASKLERTQLSPEAKVKPERNSLSAKKGRVFCTACEKTFYDKGTLKIHYNAVHLKIKHKCTIEGCNMVFSSLRSRNRHSANPNPRLHMPMNRNNRDKDLRNSLN--LASSETYKRPGFTVVSPDCGPLPGYTGSVEDSKGQPAFSSIGQNGVLFPNLKTVQPVLPFYRSPATPAELANTPGMLPSLPLLSSSIPEQLVSTDMPFDALPKKKSRKSSMPIKIEKEAVEIAEEKRHSLSSDDEVPLQVVSEDEPEDSSPRSDRVPEEQHTQLS-LEEPLPQGERACHLESVIESHGALSRTLEQTTLT-EREAEQKVALSSVMPREVEDGGHERHFTAGLVPQIPFPDYMELQQRLLAGGLFGALSNRGMAFPFLEESKELEHLGEHALVRQKEEARFQCDICKKTFKNACSMKTHEKNTHARETHACTVEGCGAAFPSRRSRDRHSSNLSLHQKVLNEEALETSEDHFRAAYLLQDVAKEAYQDVAFTPQASQTSVIFKGTSGMGSLVYPISQVHSASLESYNSGPPSEGTILDLSTTSSMKSESSSHSSWDSDGVSEEGTALMEDSDGNCEGQSLVSGEDEYPLCVLMEKADQSLASLPSGLPITCHLCQKIYSNKGTFRAHYKTVHLRQLHKCKVPGCNTMFSSVRSRNRHSQNPNLHKSLASSPSHLQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2KIM8-1", "uniprot_id": "A0A0G2KIM8_DANRE", "id": "A0A0G2KIM8-1", "name": "", "aln": "------------------------------MSEAICCTVVNCNCDSFKPGKLRRRLCEHCRHGWVAHALSKLKVHHMYQGSQVEIVHSNVVFDICSLMLYGTQAIPVRLKILLDRLFSVLKQEEVIQILNALDWTLQDYIRGYVLQDVAGKVLDRWAIMTFEEEIVTLQQFLRFGETKSIVELMALQDKEGQAVVVSTTKTNSDIRSFIESSTQRSVRLPAKADAPGCSNGHHFETLVNSMALMLPLQLMNSVPAPLLSCNTDSDHQEVQNRHDASEISLDSVSPFESG----------PVRTDVLLNSESPKMESEEFNVSGNSSPSTNCTPSVHSEITHLSPESKIRCAEKSGSLKKGRVFCSACEKTFYDKGTLKIHYNAVHLKIKHKCTIEGCNMVFSSLRSRNRHSANPNPRLHMPMNRNNRDKDLRGGLSPGLEDGQEDEKREF-IPIPESRNVSSFIIRNSEPKLHGSLSGLSQSGILFPNLKTVQPVLPFYRSLVTPAELAHTPGSLPSLPLLSSSVPAG--SRHMLMDTVPKKKSRKSSMPIKIEKD--ELAEEG---VSEEETPPLSPCTENCGVSNSGRED----GEDLLLTTVDTQDTQWHKLTHEDSCIISPSSPS------IFHIKQNSEKEESLKCEEP----------ACSSRPEPCSHWPARFTQHSENCADGGSDPESVG------LDDKEELSHP---------------CEICSKTFKNPYSVKMHYRNVHLKEMHMCTVDGCNAAFPSRRSRDRHGANLNLHHRLLTKDHSGTSS------------LRREPPDLLHQQPLGQMSGVLKGSQRTG-LVFPMSKSLEP-----EEGAVENEAVLDLSTRG------SSQSSWDSG--SDEG-LPLEDSEESCDG----------------PAASPSLQQSHS-SSITCHICQKVYSNKGTFRAHYKTVHLRLLHKCKIPGCDTTFSSVRSRNRHSQNPNLHRNLAGNISLKQE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*** **: *.*:.*****:.:* *::*:***********:: :* ******:*******.***************************:**:***:*****************.:*****:*:*** ***:.*******************:*:** *::::..:.:* ***:****. :** **: .* . .. * **.*:..*::***:*::*.:*..*:.. .:: *.:.::.: . : .** .. *..: **. .. :.*: * : * *:. . : * *:****:*:: .:* . *******:*******************************************************************..*. * ..: : * : *:. ..: .:.* : ::..:.*.*:***************** .****:*:*** **********:* * .* :*::****************: *:*:* :*.:: **. :*: * :.. :. : .: .: * :* * * .: * ::::*: :* * :. * :. : :.. *.* .. * *::.:**.* *:**.*****. *:* * :* * :* * ***:**.*:**********.:**.**:: *.:: :*. :. *: . .* * ::**:. * **:*::: .. :.*. .: ::***** . **:*****. *:** :***: .*:* *. ** . * .****:*** ***************** *****:***:* *****************:.**.. * * ", "identical_positions": 453, "similar_positions": 234, "identity": "45.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-373", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P01034-1", "uniprot_id": "CYTC_HUMAN", "id": "P01034-1", "name": "Cystatin-C", "aln": "MAGPLRAPLLLLAILAVALAVSPAAGSSPGKPPRLVGGPMDASVEEEGVRRALDFAVGEYNKASNDMYHSRALQVVRARKQIVAGVNYFLDVELGRTTCTKTQPNLDNCPFHDQPHLKRKAFCSFQIYAVPWQGTMTLSKSTCQDA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A4C9-1", "uniprot_id": "B8A4C9_DANRE", "id": "B8A4C9-1", "name": "", "aln": "-----MFLKIIVAFLAVILTVSSAG---------LVGGPTDADMDKD-SQSALQFAMAQYNRQSNDAYVRGVSKVTKLQKQVVAGIKYIFTVDVARTTCRKGG-VEELCAIHENPEIAQVKECKIVVWTKLWENFIKVTENSCL--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::*:*** *:**.*. ***** **.:::: : **:**:.:**: *** * . :*.: :**:***::*:: *::.**** * : *.:*::*.: : *.: ::: *:. :.:::.:* ", "identical_positions": 44, "similar_positions": 53, "identity": "30.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3731", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q00839-1", "uniprot_id": "HNRPU_HUMAN", "id": "Q00839-1", "name": "Heterogeneous nuclear ribonucleoprotein U", "aln": "MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSLDLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQ-QQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGGGGGGRPGAPAAGDGKTEQKGGDKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKK-ALPPEKKQN--TGSKKSNKNKSGKNQFNRGG----GHRG--RGGFNMRGGNFRGGAPGNRGGYNRR-------GNMPQRGGGGGGSGGIGYPYPRAPVFPG--RGSYSNRG---NYNRGGMPNRGNYNQNFRGRG-NNRGYKN------QSQGYNQ-WQQGQFWGQKPWSQHYHQGYY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VEK3-1", "uniprot_id": "HNRPU_MOUSE", "id": "Q8VEK3-1", "name": "Heterogeneous nuclear ribonucleoprotein U", "aln": "MSSSPVNVKKLKVSELKEELKKRRLSDKGLKADLMDRLQAALDN-EAGGRPAMEPGNGSLDLGGDAAGRSGAGLEQEAAAG-----AEDDEEEEGIAALDGDQMELGEENGAAGAADAGAMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQSQPPAAAAQQQPSQQRGAGKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGG-------------------DGKTEQKGGDKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFETDEVELSYAKNGQDLGVAFKISKEVLADRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEDCTFIQNVPLEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKK-ALPPEKKQN--TGSKKSNKNKSGKNQFNRGG----GHRG--RGGFNMRGGNFRGGAPGNRGGYNRR-------GNMPQRGGGGG-SGGIGYPYPRGPVFPG--RGGYSNRG---NYNRGGMPNRGNYNQNFRGRG-NNRGYKN------QSQGYNQ-WQQGQFWGQKPWSQHYHQGYY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F3J2-1", "uniprot_id": "E7F3J2_DANRE", "id": "E7F3J2-1", "name": "", "aln": "--MSAINVKKLKVNELKDELKKRSLSDKGLKADLMSRLQAALDEEALSGTNGSE---RRYEDGGDPAGKD---LEEDPVGES----MEEEEEDGGNAEAEHDDIMEEEEEDAGVEMDKS---DEDALLKDDDGDDD--EDEEMEKFDEDDVALDK-GDADK-----------------------------------------------------------------------DKKDEQK---NKKGVKRRRDEHGRAYFEFIEERKYSRAKSPQPPLEEEDEEFDDTTVCLDTYNCDLHFKVSRDRYSASSLTMESFAYLWAGGRGSYGVDKGKACFEMKVIEKIPVKHISSKGIEDHDVLVGWSLANSSYLLGEEAYSYAFSMTAKKTSNAVTEDYGETFDENDVVGCFINFDGAEVEISFSKNGEDLGKAFTVSKDELKGKPLFPHVLCHNCAVEFNFGQQESPFFAQPDGFTLLQQIPVHDRIRGPKGPENKKDCEVIVVVGLPGSGKTEWVTKHTEANPGKYNILGTDTILEKMMISTLKRQMKDVTKLLEISLRAPLFLGKFIEIAARKKRNYILDQTNVSASARKRKMCLFAGFQRKAVVVCPTDEEYKKRTLKKAETDGKKVPEQAIRKTKRIYSLPVEGDCFSEVLYVELQKEEVAKLLEQYKEDSKICSLEPKPIQAGVQSKRRSSKGRGGKNMFNRGGEGGLAQRGGGRGGFPHRG-NFMG-VPIPRGGFRRPPIDFLPPHAFREVFSRGSFSRGMVMPNRGGAPRPGPGRGNMGNRGGAMHREHMGHGGGGNFNQKFRGRGGNNRGFKNGNFRMSKAQAFNESWQQG-FCNRKPWSHPYSPSYY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.:*******.***:***** ********:**.*******: .* . * : ***.**:. **::... *::**: * : : *:: **:.*. * . :*:* :*::***: :: * * **:: * *: *..:: * * *** :*:**** *::***.***:***.***********:*****.****.*************:**** ***********:******.****.***.****** *****:*: :*.*: *:* :****:.*. ***** :**.:*:.. **.*. ******.******: ** **: ***:*::***:*** **.:**: * .:*******************:*.*:*. *: *::*::*:.**:*******:******::::****:*** *****: **********:**::***:: :*:** *. ** : *** **************:*********:*::******************.**:**:** ****.:**.:**:*: * * ::** .:**.*: ********. ********:** :* *: * ..::*.*.:.*** ***** .:** **** ** ** * .* ***:.* : : . *. * *: * .. ** **. .*** : :: * . **:**:***** ****:** ::*.:*: **** * .:****: * .**", "identical_positions": 437, "similar_positions": 178, "identity": "51.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3745", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54759-1", "uniprot_id": "EPHA7_RAT", "id": "P54759-1", "name": "Ephrin type-A receptor 7", "aln": "---------------------------------------------------MVVQTRYPSWIILCYIWLLGFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPSGWEEISG-LDENYT------PIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRN--IRENLYVKIDTIAADES-FTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCWSIIENLAVFPDTVTGSEFSSLVEVRGTCVSSAEEEAENSPRMHCSAEGEWLVPIGKCICKAGYQQ--KGDTCEPCGRRFYKSSSQDLQCSRCPTHSFSDREGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNL-IFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQR-----LFAAVS------------------ITTGQAAPSQVSG------VMKERVLQRS---VELSWQEPEHPNGVITEYEIKYYEKDQRERT-YSTLKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEASGKMFEATAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFKFPG--------------------------TKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPG--KRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPSSLKTPLGTCSRPISPLLDQSTPDFTAFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIDDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61772-1", "uniprot_id": "EPHA7_MOUSE", "id": "Q61772-1", "name": "Ephrin type-A receptor 7", "aln": "---------------------------------------------------MVVQTRFPSWIILCYIWLLGFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPSGWEEISG-LDENYT------PIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRN--IRENLYVKIDTIAADES-FTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCWSIVENLAVFPDTVTGSEFSSLVEVRGTCVSSAEEEAENSPRMHCSAEGEWLVPIGKCICKAGYQQ--KGDTCEPCGRRFYKSSSQDLQCSRCPTHSFSDREGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNL-IFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQR-----LFAAVS------------------ITTGQAAPSQVSG------VMKERVLQRS---VQLSWQEPEHPNGVITEYEIKYYEKDQRERT-YSTLKTKSTSASINNLKPGTVYVFQIRAVTAAGYGNYSPRLDVATLEEASGKMFEATAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFKFPG--------------------------TKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPG--KRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKDRAERPKFEQIVGILDKMIRNPSSLKTPLGTCSRPLSPLLDQSTPDFTAFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIDDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15375-1", "uniprot_id": "EPHA7_HUMAN", "id": "Q15375-1", "name": "Ephrin type-A receptor 7", "aln": "---------------------------------------------------MVFQTRYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISG-LDENYT------PIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRN--IRENLYVKIDTIAADES-FTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCICKAGYQQ--KGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNL-IFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQR-----LFAAVS------------------ITTGQAAPSQVSG------VMKERVLQRS---VELSWQEPEHPNGVITEYEIKYYEKDQRERT-YSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFKFPG--------------------------TKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPG--KRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P2N6-1", "uniprot_id": "A0A8M9P2N6_DANRE", "id": "A0A8M9P2N6-1", "name": "Ephrin type-A receptor 7", "aln": "---------------------------------------------------MVCTSVSCVWIIFC-LHLCFYVNTGIAQNTREVILLDSKAQQTELEWISSPPSGWEEISG-LDENYT------PIRTYQVCQVMEPNQNNWLRTNWIEKGDAQRIFVELKFTLRDCNSLPGVVGSCKETFNLYYQETDVEVGRN--IRESQYVKIDTIAADES-FTQGDLGERKMKLNTEVRIIGPLSRRGFYLAFQDVGACIALVSVKVYYKKCWSIIENLATFPDTVTGSEFSSLVEVEGTCVNDAEEEADNSPKMHCSAEGEWLVPIGKCICKAGFHQ--KGDACEPCGRGFYKSSSQDLQCSRCPAHSYNDREGSWRCDCEDGYYRALSDPPSVSCTRPPSAPQNL-LYNINHTTVSLEWTPPADTGGRNDVTYRIICRRCTWEPEECFPCGSNVGYSPQQSGLTDTYVTITDLLAHANYTFEVEAVNGVSDLSRTQR-----LFAAVS------------------IATSQAAPSQVSE------VIKERVQQHS---VQLSWQEPDQPNGVITEYEIKYYEKDQKDRI-YSTVKSKSTSATVNNLKPSTAYVFQIRAFTAAGYGIFGPRLEVTTKEESTG---SATVISSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFQFKFPG--------------------------TKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPG--KRDVSVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEYMENGSLDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIDDDPEAVYTTTGGKIPVRWTAMEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPPGLHQLMLDCWQKDRADRPKFDQIVGILDKMIRNPNTLKTPMGTCLRPISPLLDQNTPDFTSFRLVSEWLEAIKMERYMDNFTAAGYSSLESVARMTIEDVMSLGISLVGHQKKIMSSIQTMRAQMLHLHGTGVQV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V4E5-1", "uniprot_id": "Q9V4E5_DROME", "id": "Q9V4E5-1", "name": "receptor protein-tyrosine kinase", "aln": "MKMVGCHPNDKKVKYDGIKSKTSSVTILTSVLNDAISALKSAFYKNQAPISEQNRSQIVSRMSLLRTILLIIISIHFKLAHADQVVLLDTTREATLEWTRYPYGPQAQTPGWVEESFTDFVKGINWRSYVVCDVAYHNVNNWLWSPFIDRGSANRLYIEIQFTIRDCSLFPGNALSCKETFSLLFYEFDAATREPPPWQTDSYRLIARIAAGEGRFNQ----NSDVDINTEVKSIA-VNKKGVYFAFRDQGACISVLAVKVYYITCPAVTENFAHFNETPTGREITIIEKQNGTCVDNAEPYET--PTYLCKGDGKWTILTGGCRCKAGYEPNYTNKTCTECPLGTFKSP-EVTKCTPCPPNSNASKTGSPFCKCASGFYRHPNDGRHMPCYSPPAAPTNLTLLFVDQTSAIISWSAPAKNESFSSETNSKIYHSDIVYKIKCNICSPNVVYNPSTDTFNETKITLTNLEPVTTYTVQIHAINSVSHINEFKRHSNESSLVAVSDIVFSNTSLLNIPLDLNEVKTGQAEIVFTTESVLLSTVFNLRILAITNKDADLEWDKPVQSDFPLEFYEVRWFPKVELDAINKSALNTKETKAHIVGLLENTEYGFQVRCKTNNGFGSYSNMIYAQTLQ-------SVGSVYDDSVQIRFIAGAIVTGVLFLVIFIIATVYFMRSKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTPIVKKLHLNVTTPLFGNSRSYVDPHTYEDPNQAIREFAREIDANYITIEAIIGGGEFGDVCRGRLKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSLDTFLRVNDGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREIEN-ASDAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVSTLDNLARQPQSLLTTRPSPESDGNHILDGQR-GQNIFISTDLWLEHIKMSRYCHHFKEANLINAQQISRLTAQQLSDMGITLVGHQKKILHQARQLDTII----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 397, "similar_positions": 318, "identity": "35.35%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3756", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZP1-1", "uniprot_id": "GEMI2_RAT", "id": "Q9QZP1-1", "name": "Gem-associated protein 2", "aln": "-----------MAWVPAESAVEELMPRLLPVEPCDLTEGFDPSVPPRTPQEYLRRVQIEAAQCPDVVVAQIDPKKLKRKQSVNVSLSG-CHPAPEGYSPTLQWQQQQVIQFSSVRQSVHKHRNHWKSQQLDSNVTMPKSEDEEGWKKFCLGERLCAEGATGPSTDESPGIDYVQVGFPPLLSIVSRMNQATITSVLEYLSNWFGERDFTPELG------RWFYALLACLEKPLLPEAHSLIRQLARRCSEVRLLVGSKDDERVPALNLLICLVSRYFDQRDLADEPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQQ4-1", "uniprot_id": "GEMI2_MOUSE", "id": "Q9CQQ4-1", "name": "Gem-associated protein 2", "aln": "-----------MAWVPAESAVEELMPRLLPVEPCDLTEGFDPSVPPRTPQEYLRRVQIEAAQCPDVVVAQIDPKKLKRKQSVNISLSG-CQPAPEGYSPTLQWQQQQVAHFSTVRQSVHKHRNHWKSQQLDSNVAMPKSEDEEGWKKFCLGERLCAEGATGPSTEESPGIDYVQVGFPPLLSIVSRMNQTTITSVLEYLSNWFGERDFTPELG------RWFYALLACLEKPLLPEAHSLIRQLARRCSEVRLLVGSKDDERVPALNLLICLVSRYFDQRDLADEPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14893-1", "uniprot_id": "GEMI2_HUMAN", "id": "O14893-1", "name": "Gem-associated protein 2", "aln": "MRRAELAGLKTMAWVPAESAVEELMPRLLPVEPCDLTEGFDPSVPPRTPQEYLRRVQIEAAQCPDVVVAQIDPKKLKRKQSVNISLSG-CQPAPEGYSPTLQWQQQQVAQFSTVRQNVNKHRSHWKSQQLDSNVTMPKSEDEEGWKKFCLGEKLCADGAVGPATNESPGIDYVQIGFPPLLSIVSRMNQATVTSVLEYLSNWFGERDFTPELG------RWLYALLACLEKPLLPEAHSLIRQLARRCSEVRLLVDSKDDERVPALNLLICLVSRYFDQRDLADEPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N4X7-1", "uniprot_id": "A0A8M1N4X7_DANRE", "id": "A0A8M1N4X7-1", "name": "Gem-associated protein 2", "aln": "----------------MKSDAEELMPRLLPVDSCD-TEEYTLTEPPRNPQEYLRFVQREASLCPDVVVAQIDPKKLK-KQSVNVSITG-CLAAPEGFSPSFKWQQQQVSRFSEVRQSVNKHRQHWKAQFLDDNVVMPKTEDEDGWKRFCFGENVCLEIQLKEEDGVNPGLDYVKTGFPPFLSIVSKLSQSTVSAVLEYLINWFEERDFVPQLG------RWLYALLACLEKPLLPEAHSLIRQLARRCSAVRANLESKDDDRLSALNLMICIVARYFEQNDLADKE-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVX0-1", "uniprot_id": "GEMI2_DROME", "id": "Q9VVX0-1", "name": "Gem-associated protein 2", "aln": "----------------MQHEPEDQTFQLQALEICEPDSSFDPQKPPESGEEYLMHMFYERKRCPAVVTKRSSKIRNNTGNTTLEMLDNPELPPFKCLLPTPEWRDEQVKSFQAARSQVLVLRKELANNNYDQSGEPPLTSDQEKWKEFCRNQ-------------------------QPLLSTLLHLTQNDLELLLEMLSKWLQDPNTTVDLLHDVWLARWLYATLVCLHLPLEPHVFSTLRYIARTCIHLRNQLKEDEVQRAAPYNLLLTLTVQVFAQNDFKDYI-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: :* .:: *: . : **.. :*** : * ** **. : . : : ::. : . .. : *: :*:::** *. .*..* *.. : *.. * :.*:: **.** .: *:** : ::.* : :** * :*: : : . :* **:** *.**. ** *...* :* :** * :* : ..: :* .. **:: :. : * *.*: * ", "identical_positions": 60, "similar_positions": 83, "identity": "20.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3758", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q92932-1", "uniprot_id": "PTPR2_HUMAN", "id": "Q92932-1", "name": "Receptor-type tyrosine-protein phosphatase N2", "aln": "MGPPLPLLLLLLLLLP-PRVLPAAPSSVPRGRQLPGRLGCLLEEGLCGASEACVNDGVFGRCQKVPAMDFYRYEVSPVALQRLRVALQKLSGTGFTWQDDYTQYVMDQELADLPKTYLRRPEASSPARPSKHSVGSERRYSREGGAALANALRRHLPFLEALSQAPASDVLARTHTAQDR---------PPAEGDDRFSESILTYVAHTSALTYPPGSRTQLREDLLPRTLGQLQPDELSPKVDSGVDRHHLMAALSAYAAQRPPAPPGEGSLEPQYLLRAPSRMPRPLLAPAAPQKWPSPLGDSEDPSSTGDGARIHTLLKDLQRQPAEVRGLSGLELDGMAELMAGLMQGVDHG--VARGSPGRAALGESGEQADGPKATLRGDSFPDDGVQDDDDRLYQEVHRLSATLGGLLQ--DHGSRLLPGALPFARPLDMERKKSEHPESSLSSEEETAGVENVKSQTYSKDLLGQQPHSEPGAAAFG-ELQNQMPGP--------SKEEQSLPAGAQEALSDGLQLEVQPS-----EEEARGYIVTDRDPLRPEEGRRLVEDVARLLQVPSSAFADVEVLGPAVTFKVSANVQNVTTEDVEKATVDNKDKLEETSGLKILQTGVGSKSKLKFLPPQAE-QEDSTKFIALTLVSLACILGVLLASGLIYCLRHSSQHRLKEKLSGLGGDPGADATAAYQELCRQRMATRPPDRPEGP------HTSRISSVSSQFSDGPIPSPSARSSASSWSEEPVQSNMDISTGHMILSYMEDHLKNKNRLEKEWEALCAYQAEPNSSFVAQREENVPKNRSLAVLTYDHSRVLLKAENSHSHSDYINASPIMDHDPRNPAYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVRQCYHYWPDEGSNLYHIYEVNLVSEHIWCEDFLVRSFYLKNLQTNETRTVTQFHFLSWYDRGVPSSSRSLLDFRRKVNKCYRGRSCPIIVHCSDGAGRSGTYVLIDMVLNKMAKGAKEIDIAATLEHLRDQRPGMVQTKEQFEFALTAVAEEVNAILKALPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P80560-1", "uniprot_id": "PTPR2_MOUSE", "id": "P80560-1", "name": "Receptor-type tyrosine-protein phosphatase N2", "aln": "MGPPLPLLLLLLLPPPLPRALPAPAS--ARGRQLPGRLGCLFEDGLCGSLETCVNDGVFGRCQKVPVMDTYRYEVPPGALLHLKVTLQKLSRTGFTWQDDYTQRVIAQELANLPKAYLWHGEASGPARSLQQNADNEKWFSLEREVALAKTLRRYLPYLELLSQTPTANAHSR--IDHET---------RPAKGEDSSPENILTYVAHTSALTYPPATRAKYPDNLL-RPFSRLQPDELSPKVDGDIDKQKLIAALGAYTAQR---LPGENDPEPRYLVHGSARAPRPFSATALSQRWPPPPGDAKDSPSMDDDTLLQSLLKDLQ-QNSEVDRLGPLKEE-KADSVAGAIQSDPAE--GSQESHGRGAEGQPREQTDAPETMLQ-----DHRLSEVDDPVYKEVNRLSFQLGDLLK--DYGSPLLPEGPLLEKSSREEIKKSEQPEEVLSSEEETAGVEHVRSRTYSKDLFERKPNSEPQPRRLEDQFQNRAPEL--------WEDEESLKLAAQGPPSGGLQLEVQPS-----EEQQ-GYILTGNNPLSPEKGKQLMDQVAHILRVPSSFFADIKVLGPAVTFKVSANIQNMTTADVIKAAADNKDQLEKATGLTILQSGIRPKGKLKLLPHQEE-QEDSTKFILLTFLSIACILGVLLASSLAYCLRHNSHYKLKDKLSGLGADPSADATEAYQELCRQRMAIRPQDRSEGP------HTSRINSVSSQFSDGPMPSPSARSSTSSWSEEPVQSNMDISTGHMILAYMEDHLKNKNRLEKEWEALCAYQAEPNSSLVAQREENAPKNRSLAVLTYDHSRILLKSQNSHGSSDYINASPIMDHDPRNPAYIATQGPLPATVADFWQMVWESGCAVIVMLTPLSENGVRQCHHYWPDEGSNLYHVYEVNLVSEHIWCQDFLVRSFYLKNLQTNETRTVTQFHFLSWYDQGVPSSTRSLLDFRRKVNKCYRGRSCPIIVHCSDGAGRSGTYVLIDMVLNKMAKGAKEIDIAATLEHLRDQRPGMVQTKEQFEFALTAVAEEVNAILKALPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A3KPJ4-1", "uniprot_id": "A3KPJ4_DANRE", "id": "A3KPJ4-1", "name": "", "aln": "MSRMARVRALLLASLS-VHALAVSIA--------DRRFGCLFED-VCKLNEVCINDAVFGQCLRYPGSDVSSFDVSPAAVQRLRSVLQKLAHRGYTWQDDITQQVISKELSQLPRVSLG-----GFANTFPHFNDNSRKLKAQKEAASRTLQRFLQGFLPSDVSSFKQSPQGRREFWKENGLRNHKVFIQPPSAQIPFLQGRPDLQTTVAQLPSGRSSFSGFEQDRSGVPLAELQQYQAGPMRAQDPGKGQTQGKLHYFSLQR------TPATKIEKLPGASRQPPKPQIEKLLLKSSASSPAR-KEALSTVDEKFIDGVVNQLGRQSVNVDTLTPKDLDKLSKVITQALRVVDGEEKVKGRDATQGEIEVKREPSQELHQMEKAEDGPTHKVTQTEETAHKSEDKDKGFISQLLEFLDRNSGTESAHPPQESFLGYINQPNAGSPLRASLENVQSRTTQREVDLMKKKMEPDTLDVEPVDAEVEQWMHSSEGSPQVKAEAQTDKEPQKQSMDKEEVEKKGVRVEVNIATYSSPHDGDFGYIIT-EDSLSTDQGLNLMEILAERVRLHVTDFLQLSVLGPAVTFRLRPNARNISTAQLARVAVEQKGQLEKESGLRILEAGLSDRGKLNHIPLVKQSQVEPGNFLILVVVSMVFIVLVLGMSGALYCLRHRSHHKLKEKLAGLGNDTGHDATAAYQDLCRQRMAVQTSERGERSEVFHPSHTSRINSVSSQFSDGPMQSPSARSSTSSWSEEPSQTNMDISTGHMILSYMEDHLQNKDRLDKEWEALCSYQAEPAVCAVGQEEQNVQRNRPHGVLVYDHSRFILKLENNQSRSDYINASPIMDHDPRNPAYISAQGPLPSTVADFWQMVWESGCVVIVMLTPLAENGLKQCHQYWPDEGSDLYHIYEVNLVSEHIWCDDFLVRSFYLKNVQTNETRTVTQFHFLSWMDQNVPESARTLLDFRRKVNKCYRGRSCPIIVHCSDGAGRSGTYILIDMVLNKMAKGAKEIDIAATLEHLRDQRSGMVQTKDQFEFALTAVAEEVNAILKALPQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : *** . :.*... : *:***:*: :* *.*:**.***:* : * * ::*.* *: :*: .****: *:***** ** *: :**::**:. * . *.. : ...: . : .* . * :* .: . .* :: *...: :. : .: *. .: : :: .:..** : .* . .: : . * :: ** : . * .. : *:* : ... . ::. * * :. ::::* * :* * . : :. :: :: . :. * :: . : . : : :: ::. .: . :. **: * .* . : . . * *: : . : . .*.: . ** . ::. :: :. : . *:::**: : .: ***:* .:.* .::* .*:: :*. ::: : * ::.********:: .* :*::* :: :.:.::*.:**: :** **::*: :.**: :* : * :. :*: *..:*:. *: ** *. ***** *:::**:**:*** *.. *** ***:******* :. :* * . *****.**********: *******:******* *:***********:******:**:**:*******:***** . *.*.*:*. :**. .**.*****.:** :*.:. ********************::*****:**************.********:***::**::*******:***:************:***********:**************** *:.**.*:*:*********************************:*****************************.******:**********************", "identical_positions": 421, "similar_positions": 274, "identity": "40.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3762", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5SWD9-1", "uniprot_id": "TSR1_MOUSE", "id": "Q5SWD9-1", "name": "Pre-rRNA-processing protein TSR1 homolog", "aln": "MAA--------HRSGPLKQQNKAHKGGRHHGGGSAQRDSKGRVGPKILCKKLKRQLSRIDQRHRASQLRKQKRESVLAEKRQLGSKDGPPHQVLVVPLHSRISLPEAFKLLQNEDLGTVYLSERGST---QSFMLLCPSLKHRWFFTYARPGDLHTLLDMAKVADTILFLLDPLEGWDSTGDYCLSCLFAQGLPTYTLAVQGLSGFPPKKQIDARKKLSKMVEKRFPEDKLLLLDTQQESGMLLRQLANQKQRHLAFRDRRAYLFAHVADFVP--SEESDLVGTLKISGYVRGRTLNVNSLLHIVGHGDFQMNQIDAPVDPFPLNPRVIKSQKKPNMAMEVCVTDAAPDMEEDLKVLMKADPDHQESLQTEAIPDPMEGEQTWPTEEELDEADDLLKQRSRVVKKVPKGTSSYQAEWILDEGDESDGEGG----------EYDDIQHEGFME------EESQDGSGE---------EEEEECETMTLGESVRDDLYDEKVDAEDEERMLEKYKQERLEEMFPDEMDTPRDVAARIRFQKYRGLKSFRTSPWDPKENLPRDYARIFQFQNFVNTRKRIFKEIEEKEAEGAEVGWYVTLHVSDVPVSVVEYFRQGAPLIAFSLLPYEQKMSVLNMVVSRNPGNTEPVKAKEELIFHCGFRRFRASPLFSQHTAADKHKFQRFLTADAAFVVTVFAPITFPPASVLLFKQRRNGMHSLIATGHLFSVDPDRMVIKRVVLSGHPFKIFTKMAVVRYMFFNREDVMWFKPVELRTKWGRRGHIKEPLGTHGHMKCSFDGKLKSQDTVLMNLYKRVFPKWTYDPYVPEPVPWVKSDISSTVSEVDME", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2NL82-1", "uniprot_id": "TSR1_HUMAN", "id": "Q2NL82-1", "name": "Pre-rRNA-processing protein TSR1 homolog", "aln": "MAA--------HRPGPLKQQNKAHKGGRHRGRGSAQRDGKGRLALKTLSKKVRKELSRVDQRHRASQLRKQKKEAVLAEKRQLGGKDGPPHQVLVVPLHSRISLPEAMQLLQDRDTGTVHLNELGNT---QNFMLLCPRLKHRWFFTSARPGDLHVVLDMAKVADTILFLLDPLEGWDSTGDYCLSCLFAQGLPTYTLAVQGISGLPLKKQIDTRKKLSKAVEKRFPHDKLLLLDTQQEAGMLLRQLANQKQQHLAFRDRRAYLFAHAVDFVP--SEENNLVGTLKISGYVRGQTLNVNRLLHIVGYGDFQMKQIDAPGDPFPLNPRGIKPQKDPDMAMEICATDAVDDMEEGLKVLMKADPGRQESLQAEVIPDPMEGEQTWPTEEELSEAKDFLKESSKVVKKVPKGTSSYQAEWILDGGSQSGGEGDE--------YEYDDMEHEDFME------EESQDESSE---------EEEE-YETMTIGESVHDDLYDKKVDEEAEAKMLEKYKQERLEEMFPDEVDTPRDVAARIRFQKYRGLKSFRTSPWDPKENLPQDYARIFQFQNFTNTRKSIFKEVEEKEVEGAEVGWYVTLHVSEVPVSVVECFRQGTPLIAFSLLPHEQKMSVLNMVVRRDPGNTEPVKAKEELIFHCGFRRFRASPLFSQHTAADKHKLQRFLTADMALVATVYAPITFPPASVLLFKQKSNGMHSLIATGHLMSVDPDRMVIKRVVLSGHPFKIFTKMAVVRYMFFNREDVLWFKPVELRTKWGRRGHIKEPLGTHGHMKCSFDGKLKSQDTVLMNLYKRVFPKWTYDPYVPEPVPWLKSEISSTVPQGGME", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FCX4-1", "uniprot_id": "E7FCX4_DANRE", "id": "E7FCX4-1", "name": "Pre-rRNA-processing protein TSR1 homolog", "aln": "MAAGGEQQQQTHRPGVYKQKNKQHKHGKHRTKGEIGRENKGRVAIVALTKKQRREMRKKDRRNTANQLRRNKKDLVLTEKRKLGSRDGPPHLVAVIALHSRVDAGAVTKMLRGEGVGGVVREDQGVTGAKDSFGLVLPRFKQRFTFYRPDTDDLHSLLDVAKIADSLVFVLDSNEGWDSYGEYCLSCLFAQGLPSHALVCQGVADLAVKKRTESRRALSRLVESRFPEARLFPVDCDQDAVLLLRHLSAQKQRRLGFRSRRSHLLAQRATYVPNNSQSGTGLGTLCVSGYIRGCPLQVNRLVHITGHGDFQLSQIDAPADPLPIVLSTSRPAK-PGRDVEMMD-GGDGEVNGDVRVLMKADPAQRESLQAEAEVDPMEGEQTWPTEAELEEAEEASKKRR--VMKVPKGTSDYQATWIIDENAEEEGDGGDDGDDDDDSCDDDDDDDDEMMDDEMDGDNESQDAGSECASEGDDDDEEEEEEEISSTGRTGADQKYDEGMNESEEGEGLRRYREARANEMFPDEVDTPLDVPSRTRFQRYRGLKSFRSSPWDPLENLPSNYSRIFQFQNFERMRRRILADAAN-EEDGAMVGWYVTLHIVDVPPSVMESFQTGKPLVLVSLLPHEQKMSVMNVLVRQHPSNTEPIKSKEELVFQCGFRRFRASAIFSQHTTGDKHKLERFLRPDAPTIMSFYAPITFPTAGVLVFKQRDNGMQDLVATGSLLSCDPRRVVLKRIVLSGHPFKINRRSAVVRYMFFNRDDILWFKPVELRTKWGRRGHIKEALGTHGHMKCVFDSQLRSQDTVLMNLYKRVYPHWTYDPYVPVPLPWVKREEPPALADIDME", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** **.* **:** ** *:*: *. *:.***:. * ** :::: : *:*: *.***::*:: **:***:**.:***** * *:.****:. . ::*:... * * .: * * :.* *: * :*:*: * . ..*** :**:**:**:::*:**. ***** *:************:::*. **::.:. **: ::*: **: **.***. :*: :* :*:: :***:*: ***::*.**.**::*:*: . :** *:.. :*** :***:** .*:** *:**.*:****:.***** **:*: :. * *. :*: .. ::: .::******* ::****:*. ************ **.**.: *: * *******.*** **:* . :. *:*. : ** :.: :*: :**** ..* **** * : *.: *: **: :: . * . *.:*:: * :******:*** **.:* ***:********:***** **** :*:******** . *: *: : : * :** ********: :** **:* *: * **: .****:******:*::* :.*.****:*:****:*:*********.:*****:.****::*** .* . : :.:******.*.**:***: ***:.*:*** *:* ** *:*:**:********* : **********:*::*******************.********* **.:*:*************:*:******** *:**:* : ..::.: .**", "identical_positions": 431, "similar_positions": 230, "identity": "51.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3767", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K490-1", "uniprot_id": "A0A0G2K490_RAT", "id": "A0A0G2K490-1", "name": "non-specific serine/threonine protein kinase", "aln": "MASD-------SPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHGQRPATEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEEN-DSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQ------KEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQ----RPLEKKPLYHYKEGMSPSEKPAWAK---------------------------------------------------------------------------------------EVEERSRLNRQSSPAMPHKVANRISD-------------PNLPPRSESFSI-------SGVQPARTPP---------------MLRPVDPQIPQLVAVKSQGPA-LTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPP----LPTRIE--KFDRSS-WLRQEEDIPP------KVPQRTTSISPALARKNSPGNG-SALGPRLGSQPIRASNPDLRRTEPVLESSLQR-----------------------TSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVR-----------------ANSKSEGSPVLPHEPSKVKPEESRDIP-----RPSRPASYKKAIDEDLTALAKELRELRIEETNRPLKKVTDYSS--------SSEESESSEEEEEDGESETHDGTVAVSDIPRLIPTGAPGKNEQYNMGMVGTHGLETSHADTFGGSISREGTLMIRETAEEKKRSGHSDSNG----FAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDTGAEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDDESSAAALFTSELLRQ--EQAKLNEARKISVVNVN--PTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHND---PEVEKKQGWITVGDLEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P83510-1", "uniprot_id": "TNIK_MOUSE", "id": "P83510-1", "name": "Traf2 and NCK-interacting protein kinase", "aln": "MASD-------SPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEEN-DSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQ------KEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKR-----------------------------KQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQ----RPLEKKPLYHYKEGMSPSEKPAWAK---------------------------------------------------------------------------------------EVEERSRLNRQSSPAMPHKVANRISD-------------PNLPPRSESFSI-------SGVQPARTPP---------------MLRPVDPQIPQLVAVKSQGPA-LTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPP----LPTRIE--KFDRSS-WLRQEEDIPP------KVPQRTTSISPALARKNSPGNG-SALGPRLGSQPIRASNPDLRRTEPVLESSLQR-----------------------TSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERSRVR-----------------ANSKSEGSPVLPHEPSKVKPEESRDIT-----RPSRPA--------DLTALAKELRELRIEETNRPLKKVTDYSS--------SSEESESSEEEEEDGESETHDGTVAVSDIPRLIPTGAPGNNEQYNMGMVGTHGLETSHADTFGGSISREGTLMIRETAEEKKRSGHSDSNG----FAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSGAEYGIGSSTKASFTPFVDPRVYQTSPTDEDEEDDESSAAALFTSELLRQ--EQAKLNEARKISVVNVN--PTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHND---PEVEKKQGWITVGDLEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKE5-1", "uniprot_id": "TNIK_HUMAN", "id": "Q9UKE5-1", "name": "TRAF2 and NCK-interacting protein kinase", "aln": "MASD-------SPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEEN-DSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQ------KEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQ----RPVEKKPLYHYKEGMSPSEKPAWAK---------------------------------------------------------------------------------------EVEERSRLNRQSSPAMPHKVANRISD-------------PNLPPRSESFSI-------SGVQPARTPP---------------MLRPVDPQIPHLVAVKSQGPA-LTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPP----LPTRIE--KFDRSS-WLRQEEDIPP------KVPQRTTSISPALARKNSPGNG-SALGPRLGSQPIRASNPDLRRTEPILESPLQR-----------------------TSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVR-----------------ANSKSEGSPVLPHEPAKVKPEESRDIT-----RPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSS--------SSEESESSEEEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISREGTLMIRETSGEKKRSGHSDSNG----FAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSGTEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQ--EQAKLNEARKISVVNVN--PTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHND---PEVEKKQGWITVGDLEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BAL6-1", "uniprot_id": "A0A8M2BAL6_DANRE", "id": "A0A8M2BAL6-1", "name": "non-specific serine/threonine protein kinase", "aln": "MASD-------SPARSLDEIDLSTLRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKCMDVTGEEEEEIKAEINMLKKYSHHRNIATYYGAFIKKNPPGVDDQLWLVMEFCGAGSVTDLIKNTKGNSLKEDWTAYISREILRGLTHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVSRRNTFIGTPYWMAPEVIACDENPDATYDYKSDLWSLGITALEMAEGAPPLCELHPMRALFLIPRNAPPRLKSKKWTKRFHSFIESCLVKNHNMRPGTDQLLKHPFIRDMANERTIRIQLKDHIDRTRKKRGERDETEYEYSGSEEEEEAMLEIGEPSSIINIPGESTLRRDFLRLQVANKERSDALRRQQLEQQQ--NEGHKHQLLAERQKRIEEQ------KEQRRRLEEQQRREREARKQQEQ---RHRYEELRREEERRQAEREQEYIRRQLEEEQRQLEILQQQLLQEQALLLEYKRKQVEEQRQADRLQRQLQQERAYLVSLQQQQQQQQQDSRPEEKKQLYHYKDAVNPSDKPAWAKKIHGPPQIKIQPSNRKQSTPLYYKLDNLGIPIGRAILNPSINQSVMQPLKPQKQNLIQRQSISPPPQYSAKKISMGPRPGFSRPPYKRVEERSKLNRQSSPALQHKVANRISD-------------PSLPPRSESFSS-------GGMQPARTPP---------------MHRPVEPQMAHLVPVRSHSSS-MSVSQSLHDQSAKGVSAFQESL--VSNRPEMPRQNSDPTSEMPPPAPRMASHEE--KPDRSSPWLR-EDAVPPKLSGTTQVPQRTTSISPALARKNSPGNGESSGGGRSASQLIRTSNPDLRRTELSLDVALQR-----------------------TSSNSSSSSSTPSSQ----GGSQPGS----SERNQPR-----------------GSGKSEGSPVALQETSKPIQEEGRELS-----KPSRPA--------DLTALAKELRELRIDEVSRPPLKLTDYSS--------SSEDSDSSEDE--DG-TVGHDGTVSVSDIPRIMPS-VQGNNESF------TSSHDDSLTDSYN-DESKDGTLRMREN-NERQRLGHGESNG----FAGHGNLPDLLQQSHSPSGTPTG------LNSQDLDSMDEFGLGGGSKASFTPFVDPRVYQTSPTDD---NDESSAAAMFANELLRQ--EQAKLNEARKISVVNVN--PTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLITRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHND---PEVEKKQGWITVGELEGCIHYKVVKYERIKFLVIALKNSVEIYAWAPKPYHKFMAFKSFTELQHRPQLVDLTVEEGQRLKVIYGSSVGFHVIDVDSGSPYDIYIPSHIQSTVTPHAIVVLPKTDGMEMLLCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSLMNW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W002-1", "uniprot_id": "Q9W002_DROME", "id": "Q9W002-1", "name": "non-specific serine/threonine protein kinase", "aln": "MAHQQQQQLAPSVNCSLDDIDLTALKDPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRLKSKKWSKKFHGFIDTVLVKDYHQRPYTENLLKHGFIKDQPTDRQVRIQLKDHIDRCKKRKQEKEREDYRYSGSDNDDDEPQLAGEHSSIVQAPGGDTLRRNFQQIQEGRLAAEQQQQHHLMAQAQAQAAAAHAAAQAQAQLQQQQQQAAAAAAAAAHAAQQAQQAAQQAQAQQPQANRQPKPPSRQQVEEPGPPARPPQRLIVVPDPPHANRPLPPTPKCGEPAGQTPQQQQRNSQNNFKPSLPPRRPEPQPQTAAGGQGSQQQ---AQPEAPPRNNRQSSGLSSSGGSASGGGGSSKPAAALPQQSNNHLG-------------------------------------------------------------------QPVNPLDPLDSSDSDSEPDEPNDRARNDGTLLASDPPKPLPGLGPVSEDANTTTPLSHGSGGPPNRPLPPTPDDDDQAGDRTLIMKRKLEQNINRLQKSASTSQANVTPSRRGDESNLLRDWDFDRFFPKNANGPRGSGRGSPTTTASLSRSSQLSTLKVDTKLQRASVAEAITRPVPRGYQPLKAEPSASQSIAKEQGSASGSGSGSGSASGSGSGGSTNSPAHKRQDSDSRLPTNFERGFRRENSDFFPLAKRYSAVFSGASASGSTAGSPSAQALQRSSAVYQRNSIYSSSISSKSKENDVPGAPGAAAAGTATASAKPGPAAATTTATKGAAPKTSKSLANFHFLRPRREKTESVIVLQNAAVRAQRLQQLQQQQQQQQLQQQQQQQNRGGGGGGGGGGGGGGSSGVGADGTGLGTPGTRTSSVLPDLLSQASPATPPRHD-----KSSSEEYQAAISSSVHSTPSKSFIASSGSGGLGLGGGTVVGGVIISSNHSPQSTISLASSSSNSRQNSPKNSISKTRSSSSITNLLHKSASSSSANLHHLTPCSSTSSASISNPLPPHAYALQQKQRSFLTFGFGAGGSGPSRRESHVNVNVTPTSHEAANDTPEIRKYKKRFNSEILCAALWGVNLLIGTENGLMLLDRSGQGKVYQLISRRRFQQMEVLEGQNILVTISGKKNRVRVYYLSWLKSKILRTDGLSDQVERRNGWINVGDLQGAVHFKIVKYERIKFLVIALKDSIEIYAWAPKPYHKFMAFKNFGELEHRPLLVDLTIEDQSRLKVIYGSAEGFHAVDLDSAEVYDIYLPKHTQGAIIPHCIVALPNSNGMQLLLCYDNEGVYVNTVGRVSKNIVLQWGEMPTSVAYIGTGQIMGWGNKAIEIRSVESGHLDGVFMHKKAQRLKFLCERNDKVFFSSAKGASSCQIYFMTLNKPGMANW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : * ***:***::*:********:*:**************.********* **** :****** ***:*****:**************.*** *********:*********:*.***::***:* ***.*******::**.:***************:******************:.**************************** :**********:****. ****::************..********:*:*:.**:: ***:: ** *::*:** **:* ..:* :********** :*:: *::. :*.****::::: ** ***:: ** .****:* ::* .. .: ::: : * * : *: * : ::* : :: *: :: : ** : : . :: ** . : : :: .::. * : : : .: : *:* :* : ...:..* .* . *: . *: ..* : .: :* : *.* * **. . .* * *. * * * :: :: :* * . : :: *: .:. *:. : :: . . :.* .*: . :.: * :*:* :* *. : **: . ...*.* .: . .. .:. . : :: * ::* ::*.*::.*.:..: . * .* * .: : ...*. :.. . : .:.:. :* * : :. *:.*::*: :: .: : : .. .. . .*. ** ** : * :* ::. .. . . . : : . * .. : .. * . * :.* . : * *. . . .. . ...:.:: .: * :*.: . .: * .:* . . :*: * **** **. .. .***************************:******************:**.*******:**** *:*********::********:.:**:.* :**:::***.**:*:*.:*:*:**************:::*****************.* :*:*:* *****:*: .*****:** ***.:*:**.. ****:*.* *. : **.** **:::**::*:**::******* **::*::************** :.******:*********:**********:****************:*.:...*.*::*****: .: **", "identical_positions": 583, "similar_positions": 366, "identity": "36.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-377", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99PG2-1", "uniprot_id": "OGFR_MOUSE", "id": "Q99PG2-1", "name": "Opioid growth factor receptor", "aln": "MDDP---ECDSTWEDESE-------EDGEDGQADDTTDEDTGDDDGDAEE---ARPSLFQSRMTRYRNWRAMQDMQRYRHNYPDLTDQDCNGD-MCNLSFYKNEICFQPNGFLIEDILQNWKDNYDLLEENHSYIQWLFPLREPGVNWHAKPLTLKEVEAFKSSKEVRERLVRAYELMLGFYGIQLEDRNTGAVCRAQNFQPRFHNLNSHSHNNLRITRILKSLGELGLEHYQAPLVRFFLEETLVQHKLPSVRQSALDYFLFAVRCRHQRRELVHFAWEHFKPRREFVWGPRDKLRRFRPQTISRPLMGLGQADKDEGPGDPSQEAGTQGRTCGSGRDLSGDSGTAEDLSLLSAKPQDVGTLDGDQRHEAK--------SPSPKESKKRKLEGNRQEQVPGEPDPQGVSEVEKIALNLEGCALSPTS----------QEPREAEQPC---LVARVANEVRKRRKVEEGA-EGDGVASN-TQVQASALSPTPSECPESQKDGNG-PEDPKSQVGPEDPKSQVGPEDP-KSQVGPEDPKSQVGPEDPKGQVEPEDPKGQVGPEDPKGQVGP--EDPKGQVGPEDPKSQVGPEDP-KSQVEPEDPKSQVE---PEDPKSQVEPEDPKSQVGPEDPQSQVG--PEQAASKSLGEDPDSDTTG--TSMSESEEL--ARIEASVEPPKP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZT2-1", "uniprot_id": "OGFR_HUMAN", "id": "Q9NZT2-1", "name": "Opioid growth factor receptor", "aln": "MDDP---DCDSTWEEDEEDAEDAEDEDCEDGEAAGARDADAGDEDEESEEPRAARPSSFQSRMTGSRNWRATRDMCRYRHNYPDLVERDCNGD-TPNLSFYRNEIRFLPNGCFIEDILQNWTDNYDLLEDNHSYIQWLFPLREPGVNWHAKPLTLREVEVFKSSQEIQERLVRAYELMLGFYGIRLEDRGTGTVGRAQNYQKRFQNLNWRSHNNLRITRILKSLGELGLEHFQAPLVRFFLEETLVRRELPGVRQSALDYFMFAVRCRHQRRQLVHFAWEHFRPRCKFVWGPQDKLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGR-VDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EYZ3-1", "uniprot_id": "E7EYZ3_DANRE", "id": "E7EYZ3-1", "name": "", "aln": "MEDDLLCEYDSTWDTESD-----------------------GDELEHSGRSRKTRPAFWSN--SSSRNLRAAKDMQNYRHGYPNINEEECPEERMTNLKFYLNEIKSSPDDVSIETFHTEWRTDYKRLERVHSYIQWLFPLREPGVNYMAAELTKKEIQAFRESEEAKSRLLDSYELMLGFYGLQLLNRETGEVKRADNWRERFANLERNMHNNLRITRILKSLGELGFEHFQAPLVRFFLEETLVRKTLSSVKRSVLDYFLFAVRDKRERRKLVRFAFQHFEPKDKFVWCPRKIQKRFKKKSEKR--QNSVVLSGESAANEDSRYKSKDG--------EADAKHCKSTADITDVKKQEDGECESRAEDPEK-----------HTESDEQHLNNGQSADVQPADTPD--EDLQNLANNNNISECEAGA-------------ADCTDPQ-----DQMDSPVRAGEPTEPAAGSASGLASG--------ASRDRTDSPE------------------------------------------CIAPSETFPQPDSDSRTG----------------------------ETNGLNHKQPEPEEPMDTLEICS----------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* : ****: :.: **: .: . :**: :.. : ** ** :** .***.**:: :.:* : **.** *** *:. ** : :* :*. ** ****************: * ** :*::.*:.*:* :.**: :*********::* :* ** * **:*:: ** **: . *****************:**:**************:: *..*::*.****:**** :::**:**:**::**.*: :*** *:. :**: .: : . . : ...: .: ..:* .. . . ..: *: * : . .**.:::*: .: : *: .:::::* * : . . : :. :* :: . ** . .: .* .. .:**. * : *: .*.:. . . * . * . ** :. . ", "identical_positions": 163, "similar_positions": 149, "identity": "23.83%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3776", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60484-1", "uniprot_id": "PTEN_HUMAN", "id": "P60484-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN", "aln": "------------------MTAIIKEIVSRNKRRYQ-EDGFDLDLTYIYPNIIAMGFPAERLEG-VYRNNIDDVVRFLDSKH-KNHYKIYNLCAERHYDTAKFNCRVAQYP-FEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRR-YVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCN-----------------------PQFVVCQLKVKIYSSNSGPTRR--EDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICS---------------------------IERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O08586-1", "uniprot_id": "PTEN_MOUSE", "id": "O08586-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN", "aln": "------------------MTAIIKEIVSRNKRRYQ-EDGFDLDLTYIYPNIIAMGFPAERLEG-VYRNNIDDVVRFLDSKH-KNHYKIYNLCAERHYDTAKFNCRVAQYP-FEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRR-YVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCN-----------------------PQFVVCQLKVKIYSSNSGPTRR--EDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICS---------------------------IERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHSQITKV----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O54857-1", "uniprot_id": "PTEN_RAT", "id": "O54857-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN", "aln": "------------------MTAIIKEIVSRNKRRYQ-EDGFDLDLTYIYPNIIAMGFPAERLEG-VYRNNIDDVVRFLDSKH-KNHYKIYNLCAERHYDTAKFNCRVAQYP-FEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRR-YVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCN-----------------------PQFVVCQLKVKIYSSNSGPTRR--EDKLMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICS---------------------------IERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHSQITKV----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1PHN1-1", "uniprot_id": "A0A8M1PHN1_DANRE", "id": "A0A8M1PHN1-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN", "aln": "----------------MAMTAKLKEIVSRNKRRYQ-EDGFDLDLTYIYPNIIAMGFPAERLEG-VYRNNIDDVVRFLDSKH-KNHYKIYNLCAERHYDASKFNCRVAQYP-FEDHNPPQLELIKPFCEDLDQWLSEDENHVAAIHCKAGKGRTGVMICAYLLHRKKFAEAQEALDFYGEVRTRDKKGVTIPSQRR-YVYYYSYLLKNKLDYKPVALLFHKMVFQTLPMFSGGTCRDSTVKNRSEVNPQGFKKGSWHWDPQFVVYQLKVKIHTSNPAHTRR--EEKHMIFEFPQPLPVCGDIKVEFFHKQSKMMKKDKMFHFWINTFFIPGPEEAGDKVENGSVVN-DVDSLSCQSQSSPAERDREKERAVAAAALDRERGGERADGEKDYLILTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNSEASTSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEEQHAQITKV----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53916-1", "uniprot_id": "TEP1_YEAST", "id": "P53916-1", "name": "Probable phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TEP1", "aln": "MREEGSELEMEKGFLKWKPVNLMKKILSLPMKKTKNDIGLRLDISYILVNLIVCSYPVNTYPKLLYRNSLDDLILFLTVYHGKGNFRIFNFRGEKEDSDYKDNDLIGIAAKFESKDFEIQELRSTLINDGKIPISPIDLETRTLVEEETNNVICERIGWLDHFPPPFELLEEIVDGIENYLSVSKNRVAVLHCRMGKGRSGMITVAYLMKYLQCPLGEARLIFMQARFKYGMTNG--------------------VTIPSQLRYLRYHEFFITHEKAAQEGISNEAVKFKFKFRLAKMTFLRPSSLITSESAIVTTKIQHYNDDRNALLTRKVVYSDIMAH-ECGGNMTFIFG---------------------------RDYLTLENDCRIEFTLGTSKSKAASSIISWTSCASCWLNIYLETLMHIIKDDSSPDYFQVERLKRDEMLGTTISWQELDGFGELSTHGLKLFQALKLEWEII", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*:*:* :: : : *: **::** *:*. .:*.: :***.:**:: ** * *.:::*:*: .*:. . * * :. . **.:: ** ..: :* . :* : .. :: : :. * . * :* :* : : .*: *:: * : :.* .* :::* : * * *. : ::. :: ::. .:: : *:* *. :: . : .... : . *: *: : : : . ..: . :: : : ::: : .. .** .. . ... :::*: . :. .: .:. .* *: . : *. * .... . . :. ", "identical_positions": 56, "similar_positions": 147, "identity": "11.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-378", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q562A2-1", "uniprot_id": "ZFR_RAT", "id": "Q562A2-1", "name": "Zinc finger RNA-binding protein", "aln": "MIPICPVVSFTYVPSRLGEDAKMATGNYFGFTHSGAAAAAAAAQYSQQPASGVAYSHPTTVASYTVHQAPVAAHTVTAAYAPAAATVAVARPAPVAVAAAATAAAYGGYPTAHTATDYGYTQRQQEAPPPPPPATTQNYQDSYSYVRSTAPAVAYDSKQYYQQPTATAAAVAAAAQPQPSVAETYYQTAPKAGYSQGATQYTQAQQARQVTAIKPATPSPATTTFSIYPVSSTVQPVAAAAT--VVPSYTQSATYSTTAVTYSGTSYSGYEAAVYSAASSYYQQQQQQQKQAAAAAAAAAATAAWTGTTFTKKTPFQNKQLKPKQPPKPPQIHYCDVCKISCAGPQVFILCIYHESQCTFTSVYSVLCNSPIDQ---KDACG--KLHLCRLCDVSCTGADAYAAHIRGAKHQKVVKLHTKLGKPIPSTEPNVVSQATSSTAVSASKPTASPSSIGASNCTLNTSSIATTSVKGLSTTGNSSLNSTSNTKVSAVPTNMAAKKTSTPKINFVGGGNKLQSTGNKAEDLKGTDCIKNNPAASAVQIPEVKQDAVSEPVTPASLAALQSDVQPVGHDYVEEVRNDEGKVIRFHCKLCECSFNDPNAKEMHLKGRRHRLQYKKKVNPDLQVEVKPSIRARKIQEEKMRKQMQKEEYWRRREEEERWR-MEIRRYEEDMYWRRMEEEQHHWDDRRRMPDGGYPHGPPGPLGLLGVRPGMP-PQPQGPAPLRRPDSSDDRYVMTKHATIYPTEEELQAVQKIVSITERALKLVSDSLSEHEK---SKNKEGD-DKKEG--GKD-----------------RSLKGVLRVGVLAKGLLLRGDRNVNLVLLCSEKPSKSLLSRIAENLPKQLAVIS---PEKYDIKCAVSEAAIILNSCVEPKMQVTITLTSPIIREENMREGDVTSGMVKDPPDVLDRQKCLDALAALRHAKWFQARANGLQSCVIIIRILRDLCQRVPTWSDFPSWAMELLVEKAISSASSPQSPGDALRRVFECISSGIILKGNPGLLDPCEKDPFDTLATMTDQQREDITSSAQFALRLLAFRQIHKVLGMDPLPQMNQRFN-IHNNRKRRRD---SDGVDGFEAEG----------KKDKKDYDNF-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88532-1", "uniprot_id": "ZFR_MOUSE", "id": "O88532-1", "name": "Zinc finger RNA-binding protein", "aln": "MIPICPVVSFTYVPSRLGEDAKMATGNYFGFTHSGAAAAAAAAQYSQQPASGVAYSHPTTVASYTVHQAPVAAHTVTAAYAPAAATVAVARPAPVAVAAAATAAAYGGYPTAHTATDYGYTQRQQEAPPPPPPATTQNYQDSYSYVRSTAPAVAYDSKQYYQQPTATAAAVAAAAQPQPSVAETYYQTAPKAGYSQGATQYTQAQQARQVTAIKPATPSPATTTFSIYPVSSTVQPVAAAAT--VVPSYTQSATYSTTAVTYSGTSYSGYEAAVYSAASSYYQQQQQQQKQAAAAAAAAAATAAWTGTTFTKKTPFQNKQLKPKQPPKPPQIHYCDVCKISCAGPQTYKEHLEGQKHKKKEAALKASQNTSSSN---NSTRGTQNQLRCELCDVSCTGADAYAAHIRGAKHQKVVKLHTKLGKPIPSTEPNVVSQATSSTAASASKPTASPSSIGASNCTLNTSSIATSSVKGLSTTGNSSLNSTSNTKVSAIPTNMAAKKTSTPKINFVGG-NKLQSTGNKTEDLKGIDCVKNTPAASAVQIPEVKQDAGSEPVTPASLAALQSDVQPVGHDYVEEVRNDEGKVIRFHCKLCECSFNDPNAKEMHLKGRRHRLQYKKKVNPDLQVEVKPSIRARKIQEEKMRKQMQKEEYWRRREEEERWR-MEIRRYEEDMYWRRMEEEQHHWDDRRRMPDGGYPHGPPGPLGLLGVRPGMP-PQPQGPAPLRRPDSSDDRYVMTKHATIYPTEEELQAVQKIVSITERALKLVSDSLSEHEK---SKNKEGD-DKKEG--GKD-----------------RALKGVLRVGVLAKGLLLRGDRNVNLVLLCSEKPSKSLLSRIAENLPKQLAVIS---PEKYDIKCAVSEAAIILNSCVEPKMQVTITLTSPIIREENMREGDVTSGMVKDPPDVLDRQKCLDALAALRHAKWFQARANGLQSCVIIIRILRDLCQRVPTWSDFPSWAMELLVEKAISSASSPQSPGDALRRVFECISSGIILKGSPGLLDPCEKDPFDTLATMTDQQREDITSSAQFALRLLAFRQIHKVLGMDPLPQMNQRFN-IHNNRKRRRD---SDGVDGFEAEG----------KKDKKDYDNF-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96KR1-1", "uniprot_id": "ZFR_HUMAN", "id": "Q96KR1-1", "name": "Zinc finger RNA-binding protein", "aln": "MIPICPVVSFTYVPSRLGEDAKMATGNYFGFTHSGAAAAAAAAQYSQQPASGVAYSHPTTVASYTVHQAPVAAHTVTAAYAPAAATVAVARPAPVAVAAAATAAAYGGYPTAHTATDYGYTQRQQEAPPPPPPATTQNYQDSYSYVRSTAPAVAYDSKQYYQQPTATAAAVAAAAQPQPSVAETYYQTAPKAGYSQGATQYTQAQQTRQVTAIKPATPSPATTTFSIYPVSSTVQPVAAAAT--VVPSYTQSATYSTTAVTYSGTSYSGYEAAVYSAASSYYQQQQQQQKQAAAAAAAAAATAAWTGTTFTKKAPFQNKQLKPKQPPKPPQIHYCDVCKISCAGPQTYKEHLEGQKHKKKEAALKASQNTSSSN---SSTRGTQNQLRCELCDVSCTGADAYAAHIRGAKHQKVVKLHTKLGKPIPSTEPNVVSQATSSTAVSASKPTASPSSIAANNCTVNTSSVATSSMKGLTTTGNSSLNSTSNTKVSAVPTNMAAKKTSTPKINFVGG-NKLQSTGNKAEDIKGTECVKSTPVTSAVQIPEVKQDTVSEPVTPASLAALQSDVQPVGHDYVEEVRNDEGKVIRFHCKLCECSFNDPNAKEMHLKGRRHRLQYKKKVNPDLQVEVKPSIRARKIQEEKMRKQMQKEEYWRRREEEERWR-MEMRRYEEDMYWRRMEEEQHHWDDRRRMPDGGYPHGPPGPLGLLGVRPGMP-PQPQGPAPLRRPDSSDDRYVMTKHATIYPTEEELQAVQKIVSITERALKLVSDSLSEHEK---NKNKEGD-DKKEG--GKD-----------------RALKGVLRVGVLAKGLLLRGDRNVNLVLLCSEKPSKTLLSRIAENLPKQLAVIS---PEKYDIKCAVSEAAIILNSCVEPKMQVTITLTSPIIREENMREGDVTSGMVKDPPDVLDRQKCLDALAALRHAKWFQARANGLQSCVIIIRILRDLCQRVPTWSDFPSWAMELLVEKAISSASSPQSPGDALRRVFECISSGIILKGSPGLLDPCEKDPFDTLATMTDQQREDITSSAQFALRLLAFRQIHKVLGMDPLPQMSQRFN-IHNNRKRRRD---SDGVDGFEAEG----------KKDKKDYDNF-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PCR6-1", "uniprot_id": "ZFR_DANRE", "id": "Q6PCR6-1", "name": "Zinc finger RNA-binding protein", "aln": "MIPICPVVSFTYVPSRLGEDAKMATGNYFGFTHG------AGAQYSQQPAAGVAYTHPTTVASYTVHQAPVAAHTVAAAYAPTAATVAVARPAPVAVAAAANAAAFGGYQPAHAATDYGYAQRQPEVPPPPPPVTSQNYQDSYSYVRSTAPAVAYDSKQYYQQPAATPAVAAAAAQPQPTVAESYYQTAPKTGYSQGATPYTQTQQTRQVTVVKPATPSPATSTFSIYPVSSAVQPVAAAAAASVVPSYSQSPTYSTNAVTYSGTSYSGYEAAVYSAASSYYQQQQQQQKQ---AAVAAAATAAWTGSTFTKKTPFQNKTLKPKQPPKPPQIHYCDVCKISCAGPQTYKEHLEGQKHKKKEAALKVSQSSSSSSGGGSSARGTQNQLRCELCDVSCTGADAYAAHIRGAKHQKVVKLHTKLGKPIPSTEPSVVSQSSTSSTAAPNKTSSSNINSSTSTSSNASSSVSASYLKSGSMAASAAQGKSSGANNVSVNS-SSIKKVNTPKINFVGG-NKLQTTASKSDESK-ADAAKTAQSAASAPAADAKNDMPDPMSPQSALAALQSDVQPVGHDYVEEVRNDEGKVIRFHCKLCECSFNDPNAKEMHLKGRRHRLQYKKKVNPDLQVEVKPSIRARKIQEEKMRKQMQKEEYWRRREEEERWR-MEMRRYEEDMYWRRMEEEQHHWEDRRRMPDGGYPQGPPGPPGLLGVRPGMPIPQPQGPVPPRRPDSSDDRYVMTKHAAIYPSEDELQAIQKIVSITERALKLVSDIITDQDAGASAKGKEEDKEKKEP--PKD-----------------RLLKGVMRVGVLAKGLLLRGDKEVNLVLLCSEKPTKNLLTRIVEHLPKQLTMVT---PEKYEVKGSIQESAIILTSCGDPKMQVTITLTSPIIREESSRDGDVTSSMVKDPADVLDRQKCLDALAALRHAKWFQARANGLQSCVIVIRILRDLCQRVPTWSAFPSWAMELLVEKAISSASGPMSPGDALRRVFECISSGILLSGAPGLIDPCEKNPTDTLAFMEEQQREDITSSAQFALRLLAFRQIHKVLGMDPLPQMNSRFN-VRNTRKRRRDN--SDGADGFEAEG----------KKDKKDYEGF-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86BI3-1", "uniprot_id": "Q86BI3_DROME", "id": "Q86BI3-1", "name": "", "aln": "----------------------MANNNYAGFNYG-------GTQYNTGQVSYPAVTNATYANAAAYQNAAVAAG--QGGYGGAAGAGAGATSGPG-------AGGYGGYGDYRSAMQYDAT------------------------------------KTFYQQSPASYNASGSTA----SVSKTHYSAPPVKNQVKGKMDKSNGGP-------KPPSSAPP-----------------------------------------AGNNYSGYDTALYNAASMYVAQQHQGNPNQKPNGGANNWYQRKMGATIPGATAIRG--MRPKAPPRPQQLHYCEVCKISCAGPQTYREHLEGQKHKKREASLKMSASANSAT----QNRG--NNYHCELCDVTCTGTDAYAAHVRGAKHQKVVKLHQKLGKPIPSEEPKKMG-----------------------------------------------------------------------KINFVPA------------AAGGAGVAKTEGGANESDAAGDLDDNLDD-----SLGENTDNIKPVGGEYIEEVKDEEGKILSFNCKLCDCKFNDPNAKEMHMKGRRHRLQYKRKVQPDLVVDFKPTPRQRRLAEARANRAMMSSHRGGDDHDGGYWEEQRNRQYNEEYDYN-------NWMSRSFGGAQRFGRMGNGPPPHFGMMPGGN---------VRRPESTDDRHAIARHAEIYPKEEELQTIQRIVSHTERALKLVSDALAEQPSDAGAANKKDKAEKPSEKDGRDNQIFSFQKDADNGGNVVRILKGVMRVGYLAKGLLLHGDNAVELVVLCAEKPTSGLLQRVANVLPDKLKEVAGDTQVNYRVEVNAEEAALIV---LDESVSVKITLTSPLLRDANPGEAATTDEGEGD-SEFLPREPCLRALADLRHAKWFQARATGLQSCVMVIRILRDLCQRVSSWQSLPQWSLELLVEKVISSAGFPISPGDCMRRIMEALSSGFLING-PGLLDPCEKDPTDALLELTKQEREDLTVSAQLFLRYIAFRQIYKVLGMEPLPAMKFPMRPWRVNRKRRRSSGKAGGAPGTETESNDIDETGSDEKVAKKEGVGGTPAST", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **..** **.:. .:**. .: * ::.* . : : ::*.*** ..*. :*.: * * ..* *..:*** ::* :*. : * :***..*: . .::* :*::::*.:.* . :* :: **.:.:*. :*..****::*:*.*** * **:* : : . * *:*:. :.::. ::** **:* *:***:**********.: : :.: . : . .: . * : *.****:***:******:************ ******** **. :. ***** . *. : . :* . :*. .:::*** :*:***:::***:: *:****:*.**********:**********:**:*** *:.**: * *:: * : .: * ... .: *. . *:*:*: :. :* .* : : ** :*: ** ***:*:***:.:::** ***.*:***::*:*** ********** :::: .*: . :* . :* * ****:*** *******:**. *:**:**:***:. ** *:.: **.:* :: :* :: .*:*:*: : .:.*.******::*: . :. .*. * .:.* *: ** *** ***********.******::***********.:*. :*.*::******.****. * ****.:**::*.:***:::.* ***:*****:* *:* : .*:***:* ***: ** :*****:*****:*** *. :. : .*****. :.*. * *:*. * **: . ", "identical_positions": 363, "similar_positions": 262, "identity": "32.21%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3785", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWF4-1", "uniprot_id": "D3ZWF4_RAT", "id": "D3ZWF4-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------MDLPGDSSPSTQPSLCRQPLARALWEARSPKRPRLQP---------------------------LGSPSSLEKASRRVLAVVLEDVMATN-----------------RVPLAHKADVPSLLNHNHQQDSVCTQSPTLPSHQVKWSLEAR------------------PPDPLHLCREP-----LSRIRQSSPTSRMRSRMAPGP--------EESPSQKTDQVPQPTLVVVLKDIASARQP-----VEGFAEDQPNLIVPAQ--------------------------------RAEPVT---------------KAGQPMPTPSDLEPPFQLSTLPADPPESP--VPEPALETPLTPTSSSLLR---------PRLSPWGLAPLFRSVRSKLESFAD----------IFLTPNKAPQPP------------------------------------PPPPPMKLELKIAISEAEQSKATEKMTSVSPRPPIRQWRTQ-CNSPAPVPKLP-----------------------------------------LGRSYSCPDLGPPDPG--SWPPVPAQSS---------------------QSRPRRHTVGCGEMARTPPPPRPCLRKEVFPLG------------------------------------GVGVSPSLATSCSANASASFFCEPAEPRLGSTKGKELR-----------------------------------------------------------------ATKDKVVSDPEKK-------TLGKVSRFRIRRTPVRLQPNLTPMGLPRPIRLNKKEFTLEEIYTNKNYQSPTARRTFETIFEEPQER-NGTLIFTSSRKLRRAVEFRDSSLPR-SRRPSRGVRTAASRTLTPN-----LAPSQDVG-------SLLQERLKELDALLLEEE-IDREHPCHL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TPN9-1", "uniprot_id": "PRR14_MOUSE", "id": "Q7TPN9-1", "name": "Proline-rich protein 14", "aln": "---------------------------------------------------------------------------------------------------------------------MDLPGNSSPFTQPSLCRQPLSRASWEARSPKRPRLQP---------------------------LGTPSSLEKASRRVLAVVLEDVMTTN-----------------RVPLTHKEDTPSPLTHNHHQDPVCTQSPALPSQQVKWSMQAR------------------PPDPLHLCREP-----LTRARQSSPALRMRSRAASGP--------EESPSKKTDQVPQPTLVVVLEDIASGRQP-----AEGFDEDQPNLIVPAQSTFRSLKGPGKHCHRRGLDLEARPTLTLSLHPRAEPVT---------------KAGQPMPTPSDLEPPFQLSTLPADPPESP--VPDPALETPVIPTSSSLLR---------PRLSPWGLAPLFRSVRSKLESFAD----------IFFTPNKTPQPP------------------------------------PPSPPMKLELKIAISEAEQSRATEKITSVSPRPPIRQWRTQ-CNSLAPVSKSS-----------------------------------------LGRSYSCPDLGPPDPG--SWPPVPSQPS---------------------QSRPRRHTVGCGEMARTPPPPRPCLRKEVFPLG------------------------------------GVGVSPSLTTSCSANAPASFFCEPAEPRLGSTKGKELR-----------------------------------------------------------------ASKDKVFSDPETK-------TMGKVSRFRIRRTPVRLQPNLTPMGLPRPIRLNKKEFTLEEIYTNKNYQSPTTRRTFETIFEEPRER-NGTLIFTSSRKLRRAVEFRDSSLPR-SRRPSRGVRTAASRTLTPN-----LAPSQDVG-------SLLQERLRELDALLLEEE-TDKEHPCHL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BWN1-1", "uniprot_id": "PRR14_HUMAN", "id": "Q9BWN1-1", "name": "Proline-rich protein 14", "aln": "---------------------------------------------------------------------------------------------------------------------MDLPGDSSPPGQPRLCRQPLTRALWGARSPKRPRLQL---------------------------PGAPSPLEKASRRVLAVVLEDVMAVH-----------------MVPVVPSKQTSIPQHHSYHQDPVHRQPPASPPRQAGWSSQAR------------------PPDPLCLCREP-----LSRIHRTSSTLRRRSRTTPGP--------EEGPSQKVDRAPQPTLVVMLEDIASPRPP-----AEGFIDETPNFIIPAQ--------------------------------RAEPMR---------------IVRQPTPPPGDLEPPFQPSALPADPLESPPTAPDPALELPSTPPPSSLLR---------PRLSPWGLAPLFRSVRSKLESFAD----------IFLTPNKTPQPP------------------------------------PPSPPMKLELKIAISEAEQSGAAEGTASVSPRPPIRQWRTQDHNTPALLPKPS-----------------------------------------LGRSYSCPDLGPPGPGTCTWPPAPPQPS---------------------RPRPRRHTVGGGEMARAPPPPRPCLRKEVFPLG------------------------------------GVGASPSLTTSCSSTASTS-FSEPAEPRLGSTKGKEPR-----------------------------------------------------------------ASKDQVLSEPETK-------TMGKVSRFRIRRTPARPQLNLTPMGLPRPIRLNKKEFSLEEIYTNKNYQSPTTRRTFETIFEEPRER-NGTLIFTSSRKLRRAVEFRDSSLPR-SRRPSRGVRAAGGRTVPPN-----VAPSPDVG-------PLLQQRLEELDALLLEEETVDREQPHWT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q4V6-1", "uniprot_id": "A0A8M9Q4V6_DANRE", "id": "A0A8M9Q4V6-1", "name": "", "aln": "MTSSAVEAEMEEEYSEDECHKLASPCVTVQLGGGSTAKKPNHDQKPAEKESPENLSAIKRWEIGPLLQSFKSKMASFTEIVMSPVRLFKPSDPLSSAPLPDHQEPLTESNIEISTRAHEVETESDPFRNGLIPKRPSSEKVQCNTAPKRHRVSPRLNFCTVSTSDNHKAVLDDIQMPSDVASNEENQINCPSTQSQAVLQDETRATSPCKAQTPFHRSRLNLSIDEPLYSKSATRLSSEINVHTDAKVVLHPLSAKKCESCGSGKRSTLLKSESNSRTSKTCLNKPDPVAPSFSTSSDFDMKDKETSTAYSRMATRKSPRKKLFSGFTVSASGELANFETRSKTLDVEMKESRSENSKECADYLSGISDPPKNTSLPQKNAKRCREAPHEKKDLQIKSDCDRMNAGEGRSVRNKNLKDDNITLEVKKLDGTYVQDRKKTKSVFTAQPLKDSYWPVDTFHSEDVDRRNSIEASEEVRQEQIVSRLRKNLKCKPSLSSINVSNATDSVSPQNGTQNDSTINGSLEHVLLKEPHKTIEPPKTRRHLRSSTDVSQKRNLRIPKRKDYSMSSVVDPAGPRKPSKRKLLPSEQSTAKEQGASHFGPRVVLKPLLLSPKTKHRKPTKNVKRPSRKDGFVQTKNGAIRGEDDTGSPEKPTEDVPVVSSTGSGSIHLKRSYSCPEIPSIEFNDYHLPRCHTHDSSTTSRSRKSLPAPLPIHHHSPSKRTRRHTVCSVEIEREIAP--LCLRKEVYPTSRGSPLSPSSPYSPSTSLTVLASCFLSSPLAFLSKSSSQGRSHASNASSGSISAASSFVASSSPSFSSPLTSTLTSCHAFTGQSSVVTPSPETPSASVSSLSSVFSQSSLETDNVHQMECEEAIAEEEERSDFDFKLSASISEEKALSDSEIKQTDTKGSQRGKVSSIRICKKIPKPQNNLTPMGLPKVIRIKKKDFSLEEIYTNKNFSKPPDGR-LETIFEVPLNRRDGSQAVVGPKKLKRFVEFPELGVARKPKKPLVGLVAGGGAQRKTAGNSVVCRTRRGVGGSSKVEEGLTLQELESLLCSKLEELDTWMALQQVTG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :*.* : : ::* :. :*** *:. . . :: .* : **: ::. :. *: . . . : *. * . : . * ***: . .. :. . ::. * :* :. . . . .. . ** * ::: * . .*: : * :* : * : : : . . *:: * *.*. .* ::* . ..:: * **. .:: ** .: : * :: *:*: :** * *. : * * *::. *:. . * :* : . :*: :. : : . * ******:: . . * .: * *.***** *: * .* ******:* . . * * : :*..: :.:* * .:.* :.*. . ::::..*:.* * **** :** :. : * ********: **::**:*:*********:..*. * :***** * :* :*: ....:**:* *** : .:.* .::* *: :... . . .** * :.*..* . *** ", "identical_positions": 143, "similar_positions": 187, "identity": "13.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3788", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAA5-1", "uniprot_id": "FAP20_RAT", "id": "D4AAA5-1", "name": "Fanconi anemia core complex-associated protein 20", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEERRLRGRLSRRRPPAGGGP---PNCRPWFLSEESKSE----PWAALLRSTVGGNTDWTPNSQPLPP---------------------LPAFPSQESLPDPESTVPPEVFTVGSKTFSWTPFPPALRGSGS-----------------------------------------------------------------------------------------------SCRLLRCPEGSPGSPAPSLKGCPALDSRQTPS-----TQECV--QSQLVLLNCPLCQKAFDPKLTQLDVDSHLAQCLAESTEDVVW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UN58-1", "uniprot_id": "FAP20_MOUSE", "id": "Q3UN58-1", "name": "Fanconi anemia core complex-associated protein 20", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEERRLRGRLSRRRPPAGGGP---PNCRPWFLSEGSKSE----PWAALLRSTVSGTADWTPNRQPLPP---------------------LPAFPSQESLPDPESTVPPEAFTVGSKTFSWTPLPPALRGSGS-----------------------------------------------------------------------------------------------SRHLFCEPEGSLGSPTPSLKGCPALNSGRTPS-----AQECVPVQSPLALLSCPLCQKAFDPKLTQLDVDSHLAQCLAECTEDVVW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NZ36-1", "uniprot_id": "FAP20_HUMAN", "id": "Q6NZ36-1", "name": "Fanconi anemia core complex-associated protein 20", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAARRPRLGLSRRRPRPAGGP---SGGRPWFLLGGDERER---LWAELLR-TVS--PELILD-HEVPS---------------------LPAFPGQEPRCGPE---PTEVFTVGPKTFSWTPFPPDLWGPGR-----------------------------------------------------------------------------------------------SYRLLHGAGGHLESPARSLPQRPAPDPCRAPR-----VEQQPSVEGAAALRSCPMCQKEFAPRLTQLDVDSHLAQCLAESTEDVTW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UUX0-1", "uniprot_id": "A0A8N7UUX0_DANRE", "id": "A0A8N7UUX0-1", "name": "", "aln": "MQCVYNRMTVMSKLKRKKLSVEDYKSEQQTLIKKLNDSRCSVALQDSSCATTSTGRERWWESSELSDAERLWALTLTALCPNLQSDDLEESIPQLPPPSSTKSPVQTVSDWRWCNGNKDVNPPPGLPAPSFLVHPPPANDPKNPSQPPAEENTRASDPPSLSDQEKHASSPDGDSVPVCSTQTTQQRKLDDGVNCLEDCKLLDDQGDRFGQARNVSETRRSQAESRTVRSVEGKSAEMGAGKSESGIRTFSGAEGPALVLETKQEASGSGSGQEAKTGAGQRAKSGVREFGLGTGTKSGIAKGAKSGLGRNSIASGSGLDLGTKSGASRSGLVLGTKSGASGSGLVLGTKSGASGSGLVLGTKSGASGSGLVLGAKSGSGQEAKSGLVRSGSGLVQSGTVQEEENGLMVFRSGLGTNARASGSKLGMETKSGTEWEAKSGIRGSGTNSVEEKIANSGSSESGLGLETKSGTEQEAKSGTRESGTNSGEEKLAKSGLGRSGANSGASRSGSGLETTRSPEGSESGLETKSGAEHRSELECCPMCLMPFPAGFTQMECDGHLAQCLSEMHDDIIW", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :. * :.. ...* .. * : * : : * * ::. . . : .. .. ... ..: . . :.:*.*: * . * .* . :* * : : : .. :. ::* : : * **:* * . :**:: *.******:* :*: *", "identical_positions": 32, "similar_positions": 61, "identity": "5.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3789", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68FX7-1", "uniprot_id": "THOC5_RAT", "id": "Q68FX7-1", "name": "THO complex subunit 5 homolog", "aln": "MSSESSKKRKPKVIRSDGTPTEGKRNRSDTEQEGRYYSEEAEVDLRDPGRDYELYKYTCQELQRLMAEIQDLKSKGSKDVAIEIEERRIQSCVHFMTLKKLNRLAHIRLKKGRDQTHEAKQKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIDLVSLEEFYSEAPPNISKAEITMGDPHQQTLARLDWELEQRKRLAEKYRECLSNKEKILKEIEVKKEYLSSLQPRLNSIMQASLPVQEYLFMPFDQAHKQYETARHLPPPLYVLFVQATAYGQACDKT-LSVAIEGSVDEAKALFKPPEDSQDDESDSDAEEE-QTT-RRRPTLGVQLDDKRKEMLKRHPLSVLLDLKCKDNSVLHLTFFYLMNLNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDHGKKTPNPANQYQFDKVGILTLRDY----VLELGHPYLWVQKLGGLHFPKEQPQHTVMADHSQSASHMETTMKLLKTRVQSRLALHKQFASLEHGIVPVTSECQYLFPAKVVSRLVKWMIMAHEDYMELHFTKDIVEAGLAGDTNLYYLALIERGTAKLQAAVVLNPGYSSIPPVFRLCLNWKGEKTNSNDDNIRAMESEVNVCYRELCGPRPSHQLLTNQLQRLCVLLDVYLETESHD-DSVEGPKEFPQEKMCLRLFRGPSRMKPFKYNHPQGFFSHR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BKT7-1", "uniprot_id": "THOC5_MOUSE", "id": "Q8BKT7-1", "name": "THO complex subunit 5 homolog", "aln": "MSSESSKKRKPKVIRSDGTPTEGKRNRSDTEQEGKYYSEEAEVDLRDPGRDYELYKYTCQELQRLMAEIQDLKSKGSKDVAIEIEERRIQSCVHFMTLKKLNRLAHIRLKKGRDQTHEAKQKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIDLVSLEEFYSEAPPSISKAEITMGDPHQQTLARLDWELEQRKRLAEKYRECLSNKEKILKEIEVKRDYLSSLQPRLNSIMQASLPVQEYLFMPFDQAHKQYETARHLPPPLYVLFVQATAYGQACDKT-LSVAIEGSVDEAKALFKPPEDSQDDESDSDAEEE-QTTKRRRPTLGVQLDDKRKEMLKRHPLSVLLDLKCKDNSVLHLTFYYLMNLNIMTVKAKVTTAVELITPISAGDLLSPDSVLSCLYPGDHGKKTPNPANQYQFDKVGILTLRDY----VLELGHPYLWVQKLGGLHFPKEQPQQTVMPDHSQSASHMETTMKLLKTRVQSRLALHKQFASLEHGIVPVTSDCQDLFPAKVVSRLVKWVIITHEDYMELHFTKDIVEAGLAGDTNLYYLALIERGTAKLQAAVVLNPGYSSIPPVFRLCLNWKGEKTNSNDDNIRAMESEVNVCYKELCGPRPSHQLLTNQLQRLCVLLDVYLETESHD-DSFEGPKEFPQEKMCLRLFRGPSRMKPFKYNHPQGFFSHR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13769-1", "uniprot_id": "THOC5_HUMAN", "id": "Q13769-1", "name": "THO complex subunit 5", "aln": "MSSESSKKRKPKVIRSDGAPAEGKRNRSDTEQEGKYYSEEAEVDLRDPGRDYELYKYTCQELQRLMAEIQDLKSRGGKDVAIEIEERRIQSCVHFMTLKKLNRLAHIRLKKGRDQTHEAKQKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIDLVSLEEFYKEAPPDISKAEVTMGDPHQQTLARLDWELEQRKRLAEKYRECLSNKEKILKEIEVKKEYLSSLQPRLNSIMQASLPVQEYLFMPFDQAHKQYETARHLPPPLYVLFVQATAYGQACDKT-LSVAIEGSVDEAKALFKPPEDSQDDESDSDAEEE-QTTKRRRPTLGVQLDDKRKEMLKRHPLSVMLDLKCKDDSVLHLTFYYLMNLNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDHGKKTPNPANQYQFDKVGILTLSDY----VLELGHPYLWVQKLGGLHFPKEQPQQTVIADHSLSASHMETTMKLLKTRVQSRLALHKQFASLEHGIVPVTSDCQYLFPAKVVSRLVKWVTVAHEDYMELHFTKDIVDAGLAGDTNLYYMALIERGTAKLQAAVVLNPGYSSIPPVFQLCLNWKGEKTNSNDDNIRAMEGEVNVCYKELCGPWPSHQLLTNQLQRLCVLLDVYLETESHD-DSVEGPKEFPQEKMCLRLFRGPSRMKPFKYNHPQGFFSHR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NY52-1", "uniprot_id": "THOC5_DANRE", "id": "Q6NY52-1", "name": "THO complex subunit 5 homolog", "aln": "MSSDAVKKRKPKVIRSEAGTPETKRGRAESEQDVRVYNEEVELEGRDPQQDYTLYKETCAALAKLMSEIQELKTSGAKDGSAEIELRRKQSSIHFITLKKLNRLAHMRLKKGRDQTHEAKQRVDVLHLQLQNLLYEVMHLQKEIGKCLEFKSQHEEIELVSEDEFFQDAPAEISRPQVTREDHHQLTLARLDWELDQRKRLAEQYKTSLSSKEKIQKAIEQKREYLSSLQPGLHNIMQASLPVQEYLSMPFEHMQKQAEVARHLPPPLYVLFVQAGAYGQACDKN-LTVSIRGDVDEAKALSRPPEDSQDDESDSDAEEEQQNTKRRRPTVGVQLDDKRKEMLRRHPLSLGIDLKCKDGSVLHLYFYYLMNLNILTVKTKVSTSVDLSGAISAGELLNSESLLNCLYASDHGNETPNPANRYQFDKVGITTFADY----VSDLGHPYVWVQKLSGLQFSSDAAQ-SELSGSALSASHMEKSMKLLRGRLQSRLALHKQFSSLEHSIVPVSSECQHLFPAKVVSGLTRWTMMSHQEFTELSFVQHVLKAGLVSETDLFFKAVVERGTARLLAAVVVNPRYPEVTPLFSLSLLWKGERSGRTDDNLRAMESEVNVFRAELQGPRPGLQLLTNQIQRLCMCLDVYLETESQVSDGSEGPKEFPREKMCLRTARGPSRLKPFKYNHPQGFFSHR-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1F4-1", "uniprot_id": "THOC5_DROME", "id": "Q9W1F4-1", "name": "THO complex subunit 5", "aln": "--------------------------------------------------METILNTQFDQLQKAIEGIKEAKSKGQ-----STDEARIATTLMFVALKHANREVKHKIKAGRDKLHLEKCKVDLSRLQLQNLLYEVSHLKKEIVRCQKFKSRDTSLELLSEAEYSSELPDMPNDAEELS--SHKQHLHRLDCELRLRKALDKQYSALLSSKQELLQDNLSHAQRYVSFAPALRTLQSATKPLHDALQLSLDVEWKLSAVVKYLPKPLYVLFIVLQSLQRVSEEQSFTAEVVGYESEAQMQELLKEKKCSTLNYRQTKKE--SGDREKIADKNNLDDS----LAPHPLHICLTIGAAGSNQLVLQIRYFDFIKCATVWGQLNCSRNANG---QGDTNFVHHLLRHLYPNDLGNELPIPGIQYELRSSDLTAEECVRYLKAKDYGKPFCWLQSMCSIATVN---SSMLYKHELNLNKNNKEIIDRIARRLNSWQRLSQQIRGLTFKDIDLYSLQENIYPAGLSCSLVQWTAITHEELHSQISDALNSSSADKGITYNSYRAVIVRGSAKMECFIRIPSNYPLEMPLWILNVHWNGCLTAQNNSAIKMMEFWTNSLQPKHLE--PNDCILYAQLFRTIYSFDIFLETEGSM----QNTIEYNKEKPYISAFAKRSRSRPYKYIKKGSVYAFKQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * : : *:: *: * . : * : : *::**: ** .: ::* ***: * * :** :********** **:*** :* :***:. .::*:* *: .: * . .: *: * *** ** ** * ::* **.*::: : : : *: * *..: .*: *::: * :.:: * ..::** ******: : :..:: ::. : * .**: *.. . . ::::* . *.: : :***. * *** : : : . ... * * : *: :: ** ::. : : *: . :* **..* *:: * *. :*:: . .: : . : *:*: *:*.: .: . . .: : :. : *::* * :*: .* . : : * : ::** : . *.:* ::*:: . .:. . * : *:: **:*:: . : : . *. *:: * : *:* : .:. :: ** .* : *. :* *: * :*::****. :.. *: :** : ** :*:** : ..::.: ", "identical_positions": 142, "similar_positions": 207, "identity": "20.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-379", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADE6-1", "uniprot_id": "D4ADE6_RAT", "id": "D4ADE6-1", "name": "Sal-like protein 2", "aln": "MSRRKQRRPQQLISDCEGPS-ASENGDASEEDHPQVCAKCCAQFSDPTEFLAHQNACCTDPPVMVIIGGQENPSNSSVSSVP------------RPEGHSRPQVMDTEHSNLPDSGSSGPPDPAWGSERRGEESSGQFLVAGTGTAAGGGGGLILASPKLGATPLPPESTPAPPPPPPPPPPPGVGSGHLNIPLILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVGAPASPSELPGTGTASSTKPLLPLFSPIKPAQTGKTLASSSSSSSSSGAEPPKQAFFHLYHPLGSQHPFSVGGVGRSHKPTPAPSPALPGSTDQLIASPHLAFPGTTGLLAAQCLGAARGLEAAASPGLLKPKNGSGELGYGEVISSLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHP--VPEHLDYVITSSG--------------------------LPYGMSVPPEKAEEEAATPGGGVERKPLVASTTALSATESLTLLSTGTSTAVAPGLPTFNKFVLMKAVE--PKSKVDENTPPGSEGSAISGVADSGSATRMQLS-KLVTSLPSWALLTN-HLKS---TGSFPFPYVLEPLGASP-----------SETSKLQQLVEKIDRQ---------------------------------GAVAVASTASGAPTTSAPAPSSS-ASGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKTSPA-ARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIP---------------NGGSTLPEGGGVAQENSSEQSTASGPGSFPQPQAQQPSAEEEISEEEEEDEE-----------EEEDVTDEDSLAGRGSESGGEKAISVRGDSEEVSG----AEEEAATSGAAPTNGKE-------VDNNEKATQQALPPPPPPPDNLDRPQPMEQGPSDVSGGMEEEAKLEGTSSP--MAALPQEGEGTSTPSVEELNLPEAMKKEPGESSSRKACEVCGQSFPTQTALEEHQKTHP---KDGPLFTCVFCRQGFLDRATLKKHMLLAHHQVPPFAPHGP----------------------QNIATLSLVPGCSSSIPSPGLSPFPRKDDPAIP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QX96-1", "uniprot_id": "SALL2_MOUSE", "id": "Q9QX96-1", "name": "Sal-like protein 2", "aln": "MSRRKQRRPQQLISDCEGPS-ASENGDASEEDHPQVCAKCCAQFSDPTEFLAHQNSCCTDPPVMVIIGGQENPSNSSASSAP------------RPEGHSRSQVMDTEHSNPPDSGSSGAPDPTWGPERRGEESSGQFLVAATGTAAGGGGGLILASPKLGATPLPPESTPAPPPPPPPPPPPGVGSGHLNIPLILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVGAPASPSELPGTGAASSTKPLLPLFSPIKPAQTGKTLASSSSSSSSSGAEPPKQAFFHLYHPLGSQHPFSVGGVGRSHKPTPAPSPALPGSTDQLIASPHLAFPGTTGLLAAQCLGAARGLEAAASPGLLKPKNGSGELGYGEVISSLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHP--VPEHLDYVITSSG--------------------------LPYGMSVPPEKAEEEAGTPGGGVERKPLVASTTALSATESLTLLSTGTSTAVAPGLPTFNKFVLMKAVE--PKSKADENTPPGSEGSAIAGVADSGSATRMQLS-KLVTSLPSWALLTN-HLKS---TGSFPFPYVLEPLGASP-----------SETSKLQQLVEKIDRQ---------------------------------GAVAVASTASGAPTTSAPAPSSS-ASGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKTSPA-ARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIP---------------NGGSALSEGGGAAQENSSEQSTASGPGSFPQPQSQQPSPEEEMSEEEEEDEE-----------EEEDVTDEDSLAGRGSESGGEKAISVRGDSEEVSG----AEEEVATSVAAPTTVKE-------MDSNEKAPQHTLPPPPPPPDNLDHPQPMEQGTSDVSGAMEEEAKLEGTSSP--MAALTQEGEGTSTPLVEELNLPEAMKKDPGESSGRKACEVCGQSFPTQTALEEHQKTHP---KDGPLFTCVFCRQGFLDRATLKKHMLLAHHQVPPFAPHGP----------------------QNIATLSLVPGCSSSIPSPGLSPFPRKDDPTMP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4I9L7-1", "uniprot_id": "A0A0R4I9L7_DANRE", "id": "A0A0R4I9L7-1", "name": "", "aln": "MSRRKQKRPQQLVNADPGGTRLMPQEDQLQVKSPSTSLASEATSSSSSSSPTSLQDCQPPLAPRPSPGGLHAPSLPNESSSPPHWPNHIASYSTSLPNAHSSLSPDFPHPSLSSQTHSPPPGQQKSTRISSHQPHSTVTSPPMGISATTTTSSLSSSSSLGAPPHQGSPSPIHQTPSSPSEQLQVPP---TLAVLLEELRVLQQRQIHQMQITEEICRQVLRLGGMVSAPDAPQGSVEGQQRDAGSSSPPNG---------VSGASLINQAPVSKPNLSQTNGGRAPYSTTSSSTSSSSSLVTSTATVHPLSLTLGLPPRYLNEKSANTPISHGNGLNFQTSPLPTVSISQDQLSHSSTVSTSNGS---------SSSSSGRQQHICRFCGKVLSSDSSLQIHLRSHTGERPYQCPVCLSRFTTRGNLKAHFLRHREQNPELSLSLLPPALSEQSQSGSGSGGSQRRRKRRAEDEEPFGVKGSVGVPDSLALGFLSGPAHPSPSSLPLPPSVDLALLSTAHSLLQLNRASAAAAASVSPSVQSSSSSITSSAMTGQLKGSKQQRFDENTPPHPTLHHGSPYSQLAHLPKILFPSGPSAHHPSLALLRPPHLTSPHLPLTFPFSSYPKPQNSSPPSSSPSSSSATSDTSKLQRLAQKLEKQPLPKSTNEGQTNTQANDISTSSNAISAYRREMMAALGLNPNPSSEPTSQEIQGSAASSLVPNQCGVCLRVLSCPRALRLHQATHLGERPFPCKLCGRSFSTKGSLRAHLATHRARPANARGQNSCPLCQRKFTNAVVLQHHIRMHLGGQLPPEVNGDLQSEDAHSQIDGISLPKSLQSLPLNMSMSSAASLLDSGAILRDPTSGDTDQLMESDQDPYENTSENSPTFTLEKQDPSRENSPLDNSVALEENHYVTVHHSKSQVVNGSAHKDEDTPLSLCTRTSSQDPLFDKKWQNGASHHTVISGPKPSLSSEALDLSPALTPPSSPGLESKPDQSSEQTTLHVNGIDHVPEFKDADSHPAPENVIEHKLKADDTQESKMEESAVEDHKKDSEKTEVTSSEAPVAQPQRSEKPYSCTECGKEYASRSGLKGHMKIHSGSMNQVAGTASSQSSGGKVAERMEESTHRKLRGEDAKNLSEESTDKLSLTEHPASTTDRTEDTA--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:*****:. * : : * : . *... . * *..:. : : * . . ** . ** .. ** * . . * *.. ... * .*. ... ..:. . . . * :* . : :*..***.* ..:* .*..*. * . .:.::****************:**:****** **.: .: .** .. * .:.**: * :* :* ..:. *... ::. : . .:. . *: : :* . . * :: *.. ::. . .: :: .: . : : .. :...*** ** .. :* ****.**:.***:**************:* ** .*********.** ****: *.:.:. * :.*: : *.* *. *: * :.. .: . .*: * :: : *. ..: : ::..*.:* .. .::.. .: :: :.: ****** . : :: . .:: :. : ** *** **.* . :***. :* .:** *:*****:*.:*:::* .*:.: ...*. **:. *:: : **** :************** . * ***** **:***:***:*.****:. *:: ** **.*****:**:******.**:*:*******:* .* :*.:. * * .*:** .* . : .. ::: *.::: * *::* : *:* ... :: ::*: ...:* . :*:.. * .: *. :: :. .: . : * *. ..: ** . .: .* . :::. : * : :.: :. * * *:: : .:. **. .::. :. . :* : . : . . :. ::*. * : : .*: ** ** : .: .* .. :: .** . . *:.. *. *.:*.: ", "identical_positions": 283, "similar_positions": 353, "identity": "24.35%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3790", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BMQ8-1", "uniprot_id": "MON1B_MOUSE", "id": "Q8BMQ8-1", "name": "Vacuolar fusion protein MON1 homolog B", "aln": "---------------MEAGGDN----------AVPAPGGVEDLVDTQFPREEAGDSERVHASTLDPGDGDPEDTGSK-----DQPSSLLSPLPQTEAASSTCEHWETAAASDSSPPGEPESNSEGQGEDPDDG-----------------------------GDPSD-------EDWRSQRKHVFVLSEAGKPIYSRYGSVEALSATMGVMTALVSFVQSAGD---AIRAIYAEDHKLVFLQQGPLLLVAVSRTPQSAAQLRGELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDS------VEQDPGALLLGAVRCVPLARPLRDALGTLLRR--CTAPGLALSVLAVGGRLITVAQERNVLAECR--LDPADLQLLLDWVGAP-AFAAG--EAWAPVCLPRFNPDGFFYAYVARLDS-----MPVCLLLLGTNREAFHAMAACRRLVEDGMHNLGALRTLGEAANFSNGPAASAPAYSVQAVGAPGLRHFLYKPLDIPEQHRQLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHST-----SRPLRLIYHVAEKE---------------------------------TLLAWVTSKFELYTCLSP-LVTKAGAILVVTKLLRWVRKEEDRLFIRYPPKYSTPPSTSADQAPNNGLFTGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G3S1-1", "uniprot_id": "A0A8I6G3S1_RAT", "id": "A0A8I6G3S1-1", "name": "Vacuolar fusion protein MON1 homolog", "aln": "---------------METGGDN----------AVPAPGGVEDLVDTQFPREEAGDSEEVHSSTLDPGDGEPEDTGSKT---KDQPSSLLSPLPQAEAPSSTCEHWKTAAS-DSSPTGEPQRSSEGQGEDPSDGDPNDGDPSDGDPNDGDPNDGDPSDGDPNDGDPSD-------EDWRSQRKHVFVLSEAGKPIYSRYGSVEALSATMGVMTALVSFVQSAGD---AIRAIYAEDHKLVFLQQGPLLLVAVSRTPQSAAQLRGELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDS------VEQDPGALLLGAVRCVPLARPLRDALGTLLRR--CTAPGLALSVLAVGGRLITAAQERNVLAECR--LDPADLQLLLDWVGAP-AFAAG--EAWAPVCLPRFNPDGFFYAYVARLDS-----MPVCLLLLGTNREAFHAMAACRRLVEDGMHNLGALRTLGEAASFSNGPAANAPAYSVQAVGAPGLRHFLYKPLDIPEQHRQLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHST-----SRPLRLIYHVAEKE---------------------------------TLLAWVTSKFELYTCLSP-LVTKAAAILVVTKLLRWVRKEEDRLFIRYPPKYSTPPSTSSDQAPNNGLFTGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7L1V2-1", "uniprot_id": "MON1B_HUMAN", "id": "Q7L1V2-1", "name": "Vacuolar fusion protein MON1 homolog B", "aln": "---------------MEVGGDT----------AAPAPGGAEDLEDTQFPSEEAREGGGVHAVPPDPEDEGLEETGSKD---KDQPPSP-SPPPQSEALSSTSRLWSPAAP-ENSPTCSPESSSGGQG-----------------------------------GDPSD-------EEWRSQRKHVFVLSEAGKPIYSRYGSVEALSATMGVMTALVSFVQSAGD---AIRAIYAEDHKLVFLQQGPLLLVAMSRTSQSAAQLRGELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDS------MEQDPGALLLGAVRCVPLARPLRDALGALLRR--CTAPGLALSVLAVGGRLITAAQERNVLAECR--LDPADLQLLLDWVGAP-AFAAG--EAWAPVCLPRFNPDGFFYAYVARLDA-----MPVCLLLLGTQREAFHAMAACRRLVEDGMHALGAMRALGEAASFSNASSASAPAYSVQAVGAPGLRHFLYKPLDIPDHHRQLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHST-----SRPLRLIYHVAEKE---------------------------------TLLAWVTSKFELYTCLSP-LVTKAGAILVVTKLLRWVKKEEDRLFIRYPPKYSTPPATSTDQAAHNGLFTGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EY38-1", "uniprot_id": "E7EY38_DANRE", "id": "E7EY38-1", "name": "Vacuolar fusion protein MON1 homolog", "aln": "---------------MDHNGQESGNMEEVKICDPSILPQCPDHTDTDVPSENHCVNEDHRTPSDPEGLLESADHSSEQDVLPQEPSTEMQKLHVEDDRSLCPGGSETDSGKASQDSALVDNSNDDSGEFVVTVLARGKMEEQGMGMKG--ASSPLSETGTPLGPPSHRNEDVTADSWRQHRKHVFVLSEAGKPIYSRYGSEEALSSTMGVMMALVSFVQSGDN---IIRSVYSDEHTVVFMQRGPLVLVSVSCSRQSEQQLRNELVYVYNQIVSMLTQASITRIFEHKKNYDLRRLLAGSEKILDGLLNL------VDSDP-SFLLCAVHCLPLASSLRDSLSQILQK--AITPNLVFSILIAKNQLLTIVQEKMVIDDAR--LEPADLHLLLNLIGASSAFQAG--EIWTPICLPSFNPDCYFYAYISYLDPP---ECTVCLVLLSTDKEAFYSVAECKRKIEEAMQTQNALKSI-----------AKAQSYSVSQVGVSDLRHFMYKPFDVPDNHRQLTQFTSPEMEAPYSSEEERMRLLDLYRDLHGRIHSA-----SRPLKLIYHVAERE---------------------------------TLLAWVTSKFELYTCFSP-LVTKTCAINAITKLLRWIKKEEERLFIRYPPKYSTTPNPSRSSKTDAH-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VR38-1", "uniprot_id": "MON1_DROME", "id": "Q9VR38-1", "name": "Vacuolar fusion protein MON1 homolog", "aln": "---------------MEVEQTS----------VRSDTNSTCEYLDAEGDPESPNLYQEADPDQEAEQQNHSIISELRDGLGTMRDNSALSPEPGQENKGLAASVESLALSTSTSAKTEDSIGGGLEEEYDYQHD----------------------------------------SLWQGQKKHIFILSEAGKPIFSLHGNEDKLATLFGVIQALVSFVQMGQD---AITSIHAGGIKFAFMQRSSLILVAASRSNMSVQQLQLQLGDVYNQILSILTYSHMTKIFERRKNFDLRRLLSGSERLFYNLLANDSSSAKVSNNIFTFLTNSIRVFPLPTTIRSQITSAIQSNCSKIKNLVFAVLIANNKLIALVR----MKKYS--IHPADLRLIFNLVECSESFKSS--ENWSPICLPKFDMNGYLHAHVSYLAD----DCQACLLLLSVDRDAFFTLAEAKAKITEKLRKSHCLEAIN-----EELQQPFNAKLYQQVVGIPELRHFLYKP-------KSTAQLLCPMLRHPYKSLTELERLEAIYCDLLHRIHNS-----SRPLKLIYEMKERE---------------------------------VVLAWATGTYELYAIFEP-VVDKATVIKYVDKLIKWIEKEYDVYFIRNHATF--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53129-1", "uniprot_id": "MON1_YEAST", "id": "P53129-1", "name": "Vacuolar fusion protein MON1", "aln": "MNLNESYLDAEIPKGQLKHSKSGNFEGIPIVATTSEPTTSVNLDETFFKKAPIAMPICDDHSVSKSTSVNSLNTTSLASRRSPLQTKKLQAKNNLLSADLAKSNDDTTRALNSPKKDFGPYLDSENDIRSRLAESIYSMETSIRGSELQRRPYVSNEIPNVFKFSKFNSNCKLNESQTLCDKNFFIFTSAGKPIYCMHGKDEQIMSYTGLVNTVISYFQVNGPSELKTISTLTSGKRLTFLDKSPILLMAQSERGESSNELLNQLDFLYSYILSSLSERQLLRLFSKRENFDLRNYLESTDFENLDEICS----LICNRMFPDLLLNSLQCLPFNHSSRLKLQNVVLQQLEKRQDIPRGTLLYGLIIAPQNKLCCVLRPRGHTLHTTDLHLLFCLISHQFQNLDETQELWVPICFPKFNSSGFLYCYIKFLPNDTHSNEKSALVLISAQKDAFFSLKSFSDELIIKLEEEKLLKKIN-----------TSKGFKLSDIPAPMVHHFIYKSKQNVQYVMPHFEVNSNIALDSSQGLEYELKLKTYYQQLHGTVVRDNGNLLSRSMLNFVRWSSKDNEDLAMDETQMDFSELDEYIIGNSSFKQESVNMVGMAWVTPTFELYLIGNNGIVDKRVLFKSARKVANWCQKHESRLFISDGAVF--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :: . . . . . . . . *:.*:::.*****:. :*. : : : *:: :::*:.* : : ..*:::..::*:: * * :* :* :: *:* *: : ::* :::*:***. * .:: : . :* ::: .*: . * : : .: . * : . : : :..:**:*:: : * * *:*:* *: . :::.:: * .*:*:..:::**.:: : :. :. : . : . ::**:**. :. . . . :* * * : **.: : . .:: . :**.* .:*** . :* * : *: .* .*. . ** . : ", "identical_positions": 66, "similar_positions": 151, "identity": "9.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3805", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W3G6-1", "uniprot_id": "Q9W3G6_DROME", "id": "Q9W3G6-1", "name": "", "aln": "------------------MKWFQVTIDMILVLSFISSST-----ANPDAKRLYDDLLSNYNKLVRPVVNVTDALTVRIKLKLSQLIDVNLKNQIMTTNLWVEQSWYDYKLKWEPKE----YGGVEMLHVPSDHIWRPDIVLYNNADGNFEVTLATKATLNYTGRVEWRPPAIYKSSCEIDVEYFPFDEQTCVMKFGSWTYDGFQVDLRHIDELNG-TNVVEVGVDLSEFYTSVEWDILEVPAVRNEK-FYTCCDEPYLDITFNITMRRKTLFYTVNLIIPCMGISFLTILVFYLPSDSG-EKVSLSISILLSLTVFFLLLAEIIPPTSLVVPLLGKFVLFTMILDTFSICVTVLVLNIHFRSPQTHTMAPWVRTVFINQLPRFLVMRRPLYPISEMIKSSRRLMVRTCNGLELRDQIPPLPPPVALSRMHHSPKTTSRSTSPHLQHRVQTYNLMDECGMGMGGGASTITGHLSSLYPPTMSTANQQTSTTSSLIDAQYHNQ-YQQTGGSLLDHPLTPTKFRQMTSTSSQTGQNGSGNGNGNGGYGGHGQSGGHHLYRQQSSCSANFSPLPQHAHQAHASTTTSDLGMANPNVIKSTTTVNSVATASTLADSCCSGTIQIHQGMGAGAACQSSELLHHQQLHHQQMHHQQQQQQQQQHHHHQRPTTSAAAAAAAAAAGGPSTSAAAAAAAAAAAAGTPPPPPPPAGVCDILPACQREGGPHCCSGRGNVRQRWHTCPELHKAMDGVTYIADQTRKEEESTRVKEDWKYVAMVLDRLFLWIFTIAVVVGTAGIILQAPTLYDTRMPIDIKLSEIASTT----AKPNVARPVL--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0S0WNY8-1", "uniprot_id": "A0A0S0WNY8_DROME", "id": "A0A0S0WNY8-1", "name": "", "aln": "-----------------------------MVHGAVAG--------NPDAKRLYDDLLSNYNKLVRPVVNTTDVLKVCIKLKLSQLIDVNLKNQIMTTNLWVEQSWYDYKLRWEPKE----YGGVHMLHVPSDHIWRPDIVLYNNADGHYEVTLMTKAIVYNNGLVIWQPPAVYKSSCSIDVEYFPYDVQTCILKLGSWTYDGFKVDLRHMDEQQG-SNVVAVGVDLSEFYMSVEWDILEVPAVRNEK-FYTCCDEPYLDITFNITMRRKTLFYTVNIIIPCMGISFLTVLTFYLPSDSG-EKVTLSISILISLHVFFLLVVEIIPPTSLVVPLLGKYLIFAMILVSISICVTVVVLNVHFRSPQTHKMAPWVKRVFIDFLPAFLFIKRPTY----NFETSKLLLKDTH----------------------------------------------------------------ACFYPYYSATN------IDRLVSSGYNNS-LPKED---LSQSIT-----------------------ANGPFGGSCQVHG---------------PVPPLTH-------------------------------------CSSDEIAAVPDMDIGPLGMKSPILNNPAFSHS-----------------------------------------------------------------------------------------KCLPKIHKSCFCVRFIAEHTKMQEDSTKVKEDWKYVAMVLDRLFLWIFTLAVVVGTAGIILQAPTLYDDRIPI-IEQKDLDFSG----TSAGRCRPPQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P09478-1", "uniprot_id": "ACH1_DROME", "id": "P09478-1", "name": "Acetylcholine receptor subunit alpha-like 1", "aln": "-------------------MGSVLFAAVFIALHFATGGL-----ANPDAKRLYDDLLSNYNRLIRPVGNNSDRLTVKMGLRLSQLIDVNLKNQIMTTNVWVEQEWNDYKLKWNPDD----YGGVDTLHVPSEHIWLPDIVLYNNADGNYEVTIMTKAILHHTGKVVWKPPAIYKSFCEIDVEYFPFDEQTCFMKFGSWTYDGYMVDLRHLKQTAD-SDNIEVGIDLQDYYISVEWDIMRVPAVRNEK-FYSCCEEPYLDIVFNLTLRRKTLFYTVNLIIPCVGISFLSVLVFYLPSDSG-EKISLCISILLSLTVFFLLLAEIIPPTSLTVPLLGKYLLFTMMLVTLSVVVTIAVLNVNFRSPVTHRMAPWVQRLFIQILPKLLCIERPKKEEPEEDQPPEVLTDVYH------------------------------------------------------------------LPPDVDKFVN----YDSKRFSGDYGIPALPASHRFDLA---------------------------AAGGISAHCFAEP---------------PLPSSLPLPG-----------------------------ADDDLFSPSGLNGDISPGCCPAAAAAAAADLSPTFEK-----------------------------------------------------------------------------------------PYAREMEKTIEGSRFIAQHVKNKDKFESVEEDWKYVAMVLDRMFLWIFAIACVVGTALIILQAPSLYDQSQPIDILYSKIAKKK----FELLKMGSENTL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25162-1", "uniprot_id": "ACH4_DROME", "id": "P25162-1", "name": "Acetylcholine receptor subunit beta-like 2", "aln": "-------------------MWHWSLLCVFLLVPLANSTAPISFEANPDTKRLYDDLLSNYNRLIRPVVNNTETLTVWLGLKLSQLIEVNLKNQVMTTNLWVKQRWFDYKLRWDPEE----YGGVEQLYVPSEHIWVPDIVLYNNWDGNYEVTLMTKATLKYTGEVFWEPPAIYKSSCEMNVEYFPYDEQICFMKFGSWTYNGAQVDLKHLDQIPG-SNLVQVGIDLTEFYLSVEWDILEVPATKNEE-YYPDTLEPFSDITFKLTMRRKTLFYTVNLIVPCVALTFLTVLVFYLPSDSG-EKVTLCISILVSLTVFFLLLAEIIPPTSLAVPLLGKYLLFTMILVSLSVWTTVCVLNIHFRSPSTHNMSPLVRKLFLHFMPKLMMMRRTQY-----------------------------------------------------------------------------------TLPDYDDSTP----------SNGYTNEIDVRDS---IS-------------------------------------------------------DFPSEFK---------------------------------------------DSQDGAYDNGMQNSVDSDNVIPRN------------------------------------------------------------------------------------------LTPEVLQALRAVRFIAQHIKDADKDNEIVEDWKFVSMVLDRFFLWLFTLSCVFGTLAIICQSPSLYDTRSPIDRQLSEIPLRKNNFMLPPDIVRQVLT-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17644-1", "uniprot_id": "ACH2_DROME", "id": "P17644-1", "name": "Acetylcholine receptor subunit alpha-like 2", "aln": "MAPGCCTTRPRPIALLAHIWRHCKPLCLLLVLLLLCETVQ----ANPDAKRLYDDLLSNYNRLIRPVSNNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSE----YGGVTELYVPSEHIWLPDIVLYNNADGEYVVTTMTKAILHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDKDNKVEIGIDLREYYPSVEWDILGVPAERHEK-YYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSG-EKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLVGLSVVITIIILNIHYRKPSTHKMRPWIRSFFIKRLPKLLLMRVPKDLLRDLAANKIN------------------------------------------------------------------------YGLKFSKTKFGQALMDEMQMNSGGSSPDSLRRMQGRVG---------------------------AGGCNGMHVTTATN--------------RFSGLVG-------------------------------------ALGGGLSTLSGYNGLPSVLSGLDDSLSDVAAR----------------------------------------------------------------------------------------KKYPFELEKAIHNVMFIQHHMQRQDEFNAEDQDWGFVAMVMDRLFLWLFMIASLVGTFVILGEAPSLYDDTKAIDVQLSDVAKQI----YNLTEKKN----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04755-1", "uniprot_id": "ACH3_DROME", "id": "P04755-1", "name": "Acetylcholine receptor subunit beta-like 1", "aln": "----------------MESSCKSWLLCSILVLVAFSLVS-----ASEDEERLVRDLFRGYNKLIRPVQNMTQKVGVRFGLAFVQLINVNEKNQIMKSNVWLRLVWYDYQLQWDEAD----YGGIGVLRLPPDKVWKPDIVLFNNADGNYEVRYKSNVLIYPTGEVLWVPPAIYQSSCTIDVTYFPFDQQTCIMKFGSWTFNGDQVSLALYNNKNF--------VDLSDYWKSGTWDIIEVPAYLNVY-EGDSNHPTETDITFYIIIRRKTLFYTVNLILPTVLISFLCVLVFYLPAEAG-EKVTLGISILLSLVVFLLLVSKILPPTSLVLPLIAKYLLFTFIMNTVSILVTVIIINWNFRGPRTHRMPMYIRSIFLHYLPAFLFMKRPRK-----------------------------------------------------------------------------------TRLRWMMEMPG--MSMPAHPHPSYGSPAELPKHISAIG--------------------------------GKQSKMEVM--------------ELSDLHH---------------------------------------PNCKINRKVNSGGELGLGDGCRRESESSDS----------------------------------------------------------------------------------------ILLSPEASKATEAVEFIAEHLRNEDLYIQTREDWKYVAMVIDRLQLYIFFIVTTAGTVGILMDAPHIFEYVDQD--RIIEIYRGK----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P18916-1", "uniprot_id": "ACHG_RAT", "id": "P18916-1", "name": "Acetylcholine receptor subunit gamma", "aln": "-----------------MHGGQGPQLLLLLLATCLGAQS------RNQEERLLADLMRNYDPHLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLRWDPKD----YEGLWILRVPSTMVWQPDIVLGNNVDGVFEVALYCNVLVSPDGCIYWLPPAIFRSSCSISVTYFPFDWQNCSLVFQSQTYSTSEINLQLSQEDGQ--AIEWIFIDPEAFTENGEWAIRHRPAKMLLDPVTPAEEAGHQKVVFYLLIQRKPLFYVINIIVPCVLISSVAILIYFLPAKAGGQKCTVATNVLLAQTVFLFLVAKKVPETSQAVPLISKYLTFLMVVTILIVVNSVVVLNVSLRSPHTHSMARGVRKVFLRLLPQLLRMHVHPRAP---------------------------------------------------------------------------------AAVQDARLRLQNGSSSGWPIMTREEGDLCLPRSELLFRQR---------------------------------------------------------------------------------------------------QRNGLVQAVLEKLENGPEMRQSQEFCGSLK-----------------------------------------------------------------------------------------QASPAIQACVDACNLMARARHQQSHFDSGNEEWLLVGRVLDRVCFLAMLSLFICGTAGIFLMAHYNQVPDLPFPGDPRPYLPLPD---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04760-1", "uniprot_id": "ACHG_MOUSE", "id": "P04760-1", "name": "Acetylcholine receptor subunit gamma", "aln": "-----------------MQGGQRPHLLLLLLAVCLGAQS------RNQEERLLADLMRNYDPHLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLRWDPKD----YEGLWILRVPSTMVWRPDIVLENNVDGVFEVALYCNVLVSPDGCIYWLPPAIFRSSCSISVTYFPFDWQNCSLIFQSQTYSTSEINLQLSQEDGQ--AIEWIFIDPEAFTENGEWAIRHRPAKMLLDSVAPAEEAGHQKVVFYLLIQRKPLFYVINIIAPCVLISSVAILIYFLPAKAGGQKCTVATNVLLAQTVFLFLVAKKVPETSQAVPLISKYLTFLMVVTILIVVNSVVVLNVSLRSPHTHSMARGVRKLFLRLLPQLLRMHVRPLAP---------------------------------------------------------------------------------AAVQDARFRLQNGSSSGWPIMAREEGDLCLPRSELLFRQR---------------------------------------------------------------------------------------------------QRNGLVQAVLEKLENGPEVRQSQEFCGSLK-----------------------------------------------------------------------------------------QASPAIQACVDACNLMARARRQQSHFDSGNEEWLLVGRVLDRVCFLAMLSLFICGTAGIFLMAHYNQVPDLPFPGDPRPYLPLPD---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07510-1", "uniprot_id": "ACHG_HUMAN", "id": "P07510-1", "name": "Acetylcholine receptor subunit gamma", "aln": "-----------------MHGGQGPLLLLLLLAVCLGAQG------RNQEERLLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLRWDPRD----YEGLWVLRVPSTMVWRPDIVLENNVDGVFEVALYCNVLVSPDGCIYWLPPAIFRSACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQEDGQ--TIEWIFIDPEAFTENGEWAIQHRPAKMLLDPAAPAQEAGHQKVVFYLLIQRKPLFYVINIIAPCVLISSVAILIHFLPAKAGGQKCTVAINVLLAQTVFLFLVAKKVPETSQAVPLISKYLTFLLVVTILIVVNAVVVLNVSLRSPHTHSMARGVRKVFLRLLPQLLRMHVRPLAP---------------------------------------------------------------------------------AAVQDTQSRLQNGSS-GWSITTGEEVALCLPRSELLFQQW---------------------------------------------------------------------------------------------------QRQGLVAAALEKLEKGPELGLSQ-FCGSLK-----------------------------------------------------------------------------------------QAAPAIQACVEACNLIACARHQQSHFDNGNEEWFLVGRVLDRVCFLAMLSLFICGTAGIFLMAHYNRVPALPFPGDPRPYLPSPD---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9V1-1", "uniprot_id": "E7F9V1_DANRE", "id": "E7F9V1-1", "name": "", "aln": "----------------MDQNLSSKIIWLWILLFRFSGAL------CNLEGSLHRDLMVGYNKNIRPVESHEDIIDVKIKMTLTNLISLNEKEETLTTCVWIEMQWRDYRLRWANRTGFEVYENITRMRLPSKTIWLPDIGLENNVDGRFEVALYANTLIDPDGSVYWLPPAIYRSSCAIKVNYFPFDWQNCSMVFRSQTYNSNEITLMLSDEDNV--TMEWIEIDPEAFTENGEWMIKHRPAKKVINKRYRPDELEHQEIIFFLIIQRKPLFYVINIIVPCVLFSSLGLLVYFLPAKAGGQKCTMTICILLGQTVFLFLIAKKVPETSQAVPLIGKYLMFVMSVTTITVMNCVVVLNVSLRTPNTHPMSNTIRKVLLNILPRVLRMTMQRWTPEQEEGDFKM------------------------------------------------------------------------FALGNGTPLRRRRRSSLGLIAKADEYMFRTARSELMFSRLK--------------------------------------------------------------------------------------------------ERKGLLKNTLEKIQNGLGGNTAQDLECSLA-----------------------------------------------------------------------------------------AASPEVQQCVSSCKHIAESTKHQNDFQSKNEEWFLVARVIDRMCFFVMALLFILGTIGIFLTGHFNQAPSQPFPGDPKKYLPEISAGDIPG---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * **: .*: :**. : : * : : : :**.:* ::: :.: :*:. * *::::* * .: : :*. :* *** * ** ** : * :. : * : * ***:::* * :.* ***:* * * : : * *:. : * .: :* : . * * ** .: * : ::**.***.:*:* * : :: : :* .:**:.:* :* :: :*:. :*::*: : :* ** .:**:.*:: * : : . : : ::* * * ** * :: .:: :* .: : . : : . ::* *. *:**. : : ** *: . ", "identical_positions": 87, "similar_positions": 120, "identity": "10.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3809", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUD9-1", "uniprot_id": "SRC_RAT", "id": "Q9WUD9-1", "name": "Proto-oncogene tyrosine-protein kinase Src", "aln": "MG----SNKSKPKDASQRRRSLEPAENVHGAGG-AFPASQTPSKPASADGHRGPNAAFVPPAAAEPKLFGGFNSSD-TVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCP-TSKPQTQGLAK---DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVS-EEPIYIVTEYMNKGSLLDFLKGETG--KYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05480-2", "uniprot_id": "SRC_MOUSE", "id": "P05480-2", "name": "Proto-oncogene tyrosine-protein kinase Src", "aln": "MG----SNKSKPKDASQRRRSLEPSENVHGAGG-AFPASQTPSKPASADGHRGPSAAFVPP-AAEPKLFGGFNSSD-TVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCP-TSKPQTQGLAK---DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVS-EEPIYIVTEYMNKGSLLDFLKGETG--KYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12931-1", "uniprot_id": "SRC_HUMAN", "id": "P12931-1", "name": "Proto-oncogene tyrosine-protein kinase Src", "aln": "MG----SNKSKPKDASQRRRSLEPAENVHGAGGGAFPASQTPSKPASADGHRGPSAAFAPA-AAEPKLFGGFNSSD-TVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCP-TSKPQTQGLAK---DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVS-EEPIYIVTEYMSKGSLLDFLKGETG--KYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1JPZ3-1", "uniprot_id": "SRC_DANRE", "id": "Q1JPZ3-1", "name": "Proto-oncogene tyrosine-protein kinase Src", "aln": "MG----GVKSKPKELGQRSRSLDDGTGGHHHHT-PNPTSFTPNRSPPVEGSRRGTQPNIIN--AEQALFGGVNSTTNSITSPNRIG-ILGGVTTFVALYDYESRTASDLSFRKGERLQIVNNTEGDWWLARSLTTGESGYIPSNYVAPSDSIQAEEWYFGKITRRDSERLLLNLENRRGTFLVRESETTKGAYCLSVLDYDNVKGLNVKHYKIRKLDSGGFYITSRTQFSTLQQLVNHYRQHADGLCHSLTDVCP-VLKPPTQGLAR---DAWEIPRDSLRLDVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVS-EEPIYIVTEYMGQGSLLDFLKGDMG--KMLRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPAECPDSLHELMLTCWRKEPEERPTFEYLQGFLEDYFTSTEPQYQPGENL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V9J3-1", "uniprot_id": "SRC42_DROME", "id": "Q9V9J3-1", "name": "Tyrosine-protein kinase Src42A", "aln": "MGNCLTTQKGEPDKPADRIKLDDPPTIGVGVG--------VPQIPMPSHAGQPPEQIRPVP----------------QIPESETAG---ANAKIFVALYDYDARTDEDLSFRKGEHLEILNDTQGDWWLARSKKTRSEGYIPSNYVAKLKSIEAEPWYFRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDYSLSVRDGD-----TVKHYRIRQLDEGGFFIARRTTFRTLQELVEHYSKDSDGLCVNLCKPCVQIEKPVTEGLSHRTRDQWEIDRTSLKFVRKLGSGQFGDVWEGLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMAYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIKEDEYEARVGARFPIKWTAPEAANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMRRPTFETLQWKLEDFYTSDQSDYKEAQAY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *.:*.. .:* : : .*. . . .. : :...: * .... *******::** ****:***:*:*:*:*:******:* .* . ********* .**:** *** **.* ::*: ** ** :*:**:*:**: :. *.*** * * .****:**:**.***:*: ** * :**:** :* :.:**** * * ** *:**:: * *** * **:: ***.* **:** * **.** *******.***.*: ** ***:****** **:***** : ******:** * :****::*:. * : *:: *:**::***:****:* **:**** * *:***:. : *:*********:::** ** **:*********** *.:*:***************.* **:*****.* *** ***:***** *.:* *:::* **:*:* .***** ** ***::** :.:*: .: ", "identical_positions": 274, "similar_positions": 122, "identity": "49.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3810", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q76I76-1", "uniprot_id": "SSH2_HUMAN", "id": "Q76I76-1", "name": "Protein phosphatase Slingshot homolog 2", "aln": "--MALVTVQRSPTPSTTSSPCASEADS--GEEECRSQPRS---ISESFLTVKGAALFLPRGNGSS---TPRISHRRNKHAGDLQQHLQAMFILLRPEDNIRLAVRLESTYQNRTRYMVVVSTNGRQDTEESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIHLDGDGGFSVSTDNRVHIFKPVSVQAMWSALQSLHKACEVARAHNYYPGSLFLTWVSYYESHINSDQSSVNEWNAMQDVQSHRPDSPALFTDIPTERERTERLIKTKLREIMMQKDLENITSKEIRTELEMQMVCNLREFKEFIDNEMIVILGQMDSPTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNPSFMRQLEEYQGILLASKQRHNKLWRSHSDSDLSDHHEPICKPGLELNKKDITTSADQIAEVKTMESHPPIPPVFVEHMVPQDANQKGLCTKERMICLEFTSREFHAGQIEDELNLNDINGCSSGCCLNESKFPLDNCHASKALIQPGHVPEMANKFPDLTVEDLETDALKADMNVHLLPMEELTSPLKDPPMSPDPESPSPQPSCQTEISDFSTDRIDFFSALEKFVELSQETRSRSFSHSRMEELGGGRNESCRLSVVEVAPSKVTADDQRSSSLSNTPHASEESSMDEEQSKAISELVSPDIFMQSHSENAISVKEIVTEIESISQGVGQIQLKGDILPNPCHTPKKNSIHELLLERAQTPENKPGHMEQDEDSCTAQPELAKDSGMCNPE-GCLTTHSSIADLEEGEPAEGEQELQGSGMHPGAKWYPGSVRRATLEFEERLRQEQEHHGAAPTCTSLSTRKNSKNDSSVADLAPKGKSDEAPPEHSFVLKEPEMSKGKGKYSGSEAGSLSHSEQNATVPAPRVLEFDHLPDPQEGPGSDTGTQ-QEGVLKDLRTVIPYQESETQAVPLPLPKRVEIIEYTHIVTSPNHTGPGSEIATSEKSGEQGLRKVNMEKSVTVLCTLDENLNRTLDPNQVSLHPQVLPLPHSSSPEHNRPTDHPTSILSSPEDRGSSLSTALETAAPFVSHTTHLLSASLDYLHPQTMVHLEGFTEQSSTTD-EPSAEQVSWEESQESPLSSGSEVPYKDSQLSSADLSLISKLGDNTGELQEKMDPLPVACRLPHSSSSENIKSLSHSPGVVKERAKEIESRVVFQAGLTKPSQMRRSASLAKLGYLDLCKDCLPEREPASCESPHLKLLQPFLRTDSGMHAMEDQESLENPGAPHNPEPTKSFVEQLTTTECIVQSKPVERPLVQYAKEFGSSQQYLLPRAGLELTSSEGGLPVLQTQGLQCACPAPGLAVAPRQQHGRTHPLRRLKKANDKKRTTNPFYNTM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SW75-1", "uniprot_id": "SSH2_MOUSE", "id": "Q5SW75-1", "name": "Protein phosphatase Slingshot homolog 2", "aln": "--MALVTVQRSPTPSTTSSPCASEADS--GEEECRSQPRS---ISESFLTVKGAALFLPRGNGSS---TPRVSHRRNKHAGDLQQHLQAMFILLRPEDNIRLAVRLESTYQNRTRYMVVVSTNGRQDTEESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIHLDGDGGFSVSTDNRVHIFKPVSVQAMWSALQSLHKACEVARMHNYYPGSLFLTWVSYYESHINSDQSSVNEWNAMQDVQSHRPDSPALFTDIPTERERTERLIKTKLREIMMQKDLENITSKEIRTELEMQMVCNLREFKEFIDNEMIVILGQMDSPTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNPSFMRQLEEYQGILLASKQRHNKLWRSHSDSDLSDHHEPICKPGLELNKKEMTTSADQIAEVKTVENLAAMPTVFMEHVVPQDANQKGLHTKERVICLEFSSQEFRAGQIEDELNLNDINGCSSGCCLSESKLPLDNCHASKALLQPGQAPDIANKFPDLAVEDLETDALKADMNVHLLPMEELTSRLKDLPMSPDLESPSPQASCQAAISDFSTDRIDFFSALEKFVELSQETRSRSFSHSRIEELGGGRSEGCRLSVIEVAASEMAADDQRSSSLSNTPHASEESSVDEDQSKAITELVSPDIIMQSHSENAISVKEIVTEIESISQGVGQVQLKGDILSNPCHTPKKSTIHELPLERVPAPESKPGHWEQDESFCSVQPELARDSGKCAPEEGCLTTHSSTADLEEEEPVEGEHDW-GPGMHSGAKWCPGSVRRATLEFEERLRQEQENHGTASAGPTLSNRKNSKNDSSVADLMPKWKSDETTPEHSFFLKEAEPSKGKGKCSGSEAGSLSHCERNPTMPDCELLEHHSLPAPQDCLGSDSRSKKQEGDLKKQRAVVPNQECDTQAILLPLPKKIEIIEYTPTVTSLGHTEPGGEATPSKEGEKQGLRKVKMEQSITMFCALDENLNRTLEPSQVSLHPQVLPLPHSSS-ECDRPAD-PNPMLSSPQDKGDCPSTPFKTAAPFVSCSTQGASFSLDYLLPHSVVHLEGCTEQSSATDNELSPEQASWEDSRGHFLSSGSGMAHTSSPLTNEDLSLINKLGDSVGVLQKKLDPSPEACRIPHSSSSENIRDLSHSRGVVKEHAKEIESRVIFQAGFSKTSQMKRSASLAKLGYLDLCKDYLPDRELVSSESPHLKLLQPFLRTDSGMHALMAHEPSESAGAQQNPQPTKYSVEQLKTSECIVQSKPVERPSVQYAKEFGYSQQCLLPKARPELTSSEGGLPLLQTQGLQYTGPSPGLAVAPRQQHGRTHPLRRLKRANDKKRTTNPFYNTM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FH10-1", "uniprot_id": "E7FH10_DANRE", "id": "E7FH10-1", "name": "protein-serine/threonine phosphatase", "aln": "MTLESVPITESSAARGFCSCCGAKIMPYFTDNAVASQNQINQLISENFLTVKGAALFLPRGNGSSSSSAPRIPQRRNKHTGDLQQHLQTMFTLLRPEDTIRLAVRLESAYAVRTRYMVIISTNGRQDTEESVVLGMDFSNSDR-TCTVGLVLPLWSDTLIHLDGDGGFSVSTVNRVHVFKPVSVQAMWSALQSLHKVCEVARCHNYYPGSLFLTWVSYYQSRVTSDQHCINEWNAMQDVQSHRADSPVLFTDVPTERERTERLIKTRLREIMMQKDLENVTSKEIRTELEMQMVCNLREFKEFIDNEMIVILGQMDSPTEIFDHVYLGSEWNASNLEELQNSGVRYILNVTREIDNFFPGLFEYHNIRVYDEEATNLLEYWNDTYKFISKAKKAGVKCLVHCKMGVSRSASTVIAYAMKEYGWDLDRAFDHVKERRSVTKPNPSFMKQLEEYQGILLASKQRHNKLWRSHSDTDLSDGHEPLCKTPRSLDRSDPHNNNGSLS-IQQMLGIAVLESLTNPRPVACNTHKK--------------SGETPSKLAHEDLFLLPQSRQRAATVGSKQ----RNSTLILAVREP-----VSHRHPPPALHVLDS---------PLLPEERGGDTTPNLGAQSSHQVPEPKTDCVELSPDLP-DQNDSY-QVSQSLELCLES---AVSKDEGNLPSSSTPEADSPSEAPAVPELVSSDD------NNNPNAADLEAADDCTDASVSRLSTDSIDFFSAREKFLCLSQDNHPCSLSETTAVQSPPARCTSPLDHPSEEPEEECHTHSEEHSDAVLQPSAHDSTVSVRHIVTELESTSQTSSPPLAHTSPQTATPEEKEEEDEE-----AAPAPHSLSDRPSGSVRRVTEQLELILRQGQEIPLSRSPLPSPCLG------------CTQSYSDE--PEDSPALSQKTP-QGKG-------------------DDTKVLDD---------------------------------------------------EDSGIIPDPSFS-------------------VFLEGSVS------------LEADQITLNPTLEPSSCSSS-----------------------------------------------------LLWLEGVTELETDVDDPLRP-QVRLARSSEDLQKIQETLRELQAFLYEAGG-----LGVSTGQVEENR-----------SSDGSGEQRFEPKAPAVWQRAMEIEARIR-QAGLTPPSLMKRSASLAKLDRLELSTNDLSDWD--------------FHPASTGLHHP-----SSSVSTFHSLPLTHSHDDAHKKQRVLPQSPSTPDSAVHLMDADRTEGSAHLLPSCPQKT-QVGGASSPEHVPIQSTVSVS----TRQQQHVKTHPVRRLRKAVDKKKTVTVLYNTM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.: .*.:. .* *.:: . :: ** : ***.****************** :**:.:*****:********:** ******.*********:* ******::***********:*******..* ***:************************ ****:******************.***** ****************:*::.*** .:*************.***.****:*************:************:***************************************:**:**:***********:*** ******************:**************:** ************** * ***************************:****:*:*****:*********:*************************:**** ***:**. .*::.: .. ..:: :: : . . : .: : *. ::::* * * : .::* * . :. .:. *. *: :* ::::.* ::. *:: *** *. . : ... : *.*:..* .*:. *: * : :.: :**. *: :.*:.. : ... *. * .... :::** .*.*:*:: .: *: . :::.* : .* : * *: :.:.: . . . * . : : . . *. . :*. :. . .** * . * . :.::: .: :* * * ... *. :. .*****.* ::* *** ** : .. .: . .: *** **.* *.: :*** .:*: * : :.. ..: * :* *:: *:..*::*:* : * . *** :: *** ** .: .* . *. * . . : .: * . . ** ..* :::: **.... : :. . .* ::* ***:*: ***:: .* *:********. *:*..: *.: : * :.:*:* .. .: :. *: : .. . : ** .. . *: . . . * : : * . ** . : :* : . . : :*** :***:***::* ***:*.. :****", "identical_positions": 540, "similar_positions": 322, "identity": "37.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3813", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NXB0-1", "uniprot_id": "MKS1_HUMAN", "id": "Q9NXB0-1", "name": "Tectonic-like complex member MKS1", "aln": "MAETVWSTDTGEAVYRSRDPVRNLRLRVHLQRITS----SNFLHYQPAAELGKDLIDLATFRPQPTASGHRPEEDEEEEIVIGWQEKLFSQFEVDLYQNETACQSPLDYQYRQEILKLENSGGKKNRRIFTYTDSDRYTNLEEHCQRMTTAASEVPSFLVERMANVRRRRQDRRGMEGGILKSRIVTWEPSEEFVRNNHVINTPLQTMHIMADLGPYKKLGYKKYEHVLCTLKVDSNGVITVKPDFTGLKGPYRIETEGEKQE---LWKYTIDNVSPHAQPEEEERERRVFKDLYGRHKEYLSSLVGTDFEMTVPGALRLFVNGEVVSAQGYEYDNLYVHFFVELPTAHWSSPAFQQLSGVTQTCTTKSLAMDKVAHFSYPFTFEAFFLHEDESSDALPEWPVLYCEVLSLDFWQRYRVEGYGAVVLPATPGSHTLTVSTWRPVELGTVAELRRFFIGGSLELEDLSYVRIPGSFKGERLSRFGLRTETTGTVTFRLHCLQQSRAFMESSSLQKRMRSVLDRLEGFSQQSSIHNVLEAFRRARRRMQEARESLPQDLVSPSGTLVS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SW45-1", "uniprot_id": "MKS1_MOUSE", "id": "Q5SW45-1", "name": "Tectonic-like complex member MKS1", "aln": "MAEAVWSTDTGEAVYRSRDPVRNLRLRVHLQRITS----SNFLHYQPAAQMGKDLIDLATFRPPQAASGHRPDEEEEEEVVIGWQEKLFSQFEVDLYQNESACQSPLDHQYRQEILKLENSGGRKNRRIFTYTDSDRYTDLEEYCQKITTSASEVPSFLAERMANVRRRRQDRRGVEGSKLKSRIVTWEPSEDFIKNNHAINTPLQTMYIMADLGPYGKLGYKVHEHVLCILKVDSNGVITVKPDFTGIKGPYRIETEGEKQEHTSAWKYTIDNVSSLAQPEEEEREQRVFKDLYGRHKEYLSSLVGTDFEMIAPGALRLFVNGEVVSAQGYEYDNLYVHFFVELPAANWSSPPFQQLSGVTQACATKSLGMDKVAYFSFPFTFEAFFLHEDESAESLPEWPVLYCKVLSLDFWQRYRVEGYGAVVLPATPGSHTLTVSTWRPMELGLVAELRRFFIGGSLELEDPSYVRIPGTFKGERLSRFGFRTETTGTVTFRLHCLQQSRAFMESNSLQKQMRSVLDRLEGFSQQSSTHNVLEAFRRARRRMQEARESLPQDLVSPTGTLT-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A3QK09-1", "uniprot_id": "A3QK09_DANRE", "id": "A3QK09-1", "name": "", "aln": "MADG-WCSDNGESVYRSRDAVKNFRIRVRIQRVTSTAALSEHLHQQVLSQQERGVIELETFSTQTASS------TDEEELVVAWQEKFFSQYEVDLYQTESNCQTPLERQYHTDIMAMERSKRRQNQRIFTYTDFDRFSKWEEQAQSLVIPAQPTPTFLAERMANVRHRRQERRPAESNVPKSRLITWEPSEEFVKNSHIINTPVQTMYIMADLGPTGKLGLKENEYVLCTIKADGNGVISIKPDFNNNRGAYRLETEGEKRE---VWRLYLENASSDIQAEEKDREQRMYRDLYTRHKDYLNSLVGQDFEMPPPGILRLIVNGEIVSAQGYEYDNLYVHFFVDLPN-NWSSVSSHCLSGVTQTCRTRSIEKEDVAFFSYPFSFETFFHKEDESDGSLPQWPVLYFKVLSLDFWQRFRTEGYGYLVIPSTSGRHRMTCRTWRAVQRGTVAELRRFFIGGAPELEDISYVRIPGTFKGERLSRFGFRTQTTGSVTFTLNCIQHARAFIDASTLKKRRQTVLDQLGGHSQQGSVYNVLEAFQRAHKRMQEARETLPRDLINTSALLNSESSA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: *.:*.**:******.*:*:*:**::**:** *:.** * :: :.:*:* ** . ::* :***:*:.****:***:******.*: **:**: **: :*: :*.* ::*:******* **::. ** .* :. .*. .*:**.*******:***:** *.. ***::******:*::*.* ****:***:******* *** * *:*** :*.*.****::****.. :*.**:******:* *: ::*.*. *.**::**:*:::*** ***:**.**** **** ** ***:****:*****************:** :*** . : ******:* *:*: :.**.**:**:**:** :**** :**:***** :*********:*.**** :*:*:*.* * :* ***.:: * ***********: **** *******:**********:**:***:*** *:*:*::***:::.:*:*: ::***:* *.***.* :******:**::*******:**:**:..:. * ", "identical_positions": 328, "similar_positions": 151, "identity": "57.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3825", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADQ2-1", "uniprot_id": "D4ADQ2_RAT", "id": "D4ADQ2-1", "name": "Mitochondrial cardiolipin hydrolase", "aln": "------MGRSSWRLVFAAG----AGLALALEALPWLMRWLLAGRR---PRREVLFFPSQ-VTCTEALLQAPGLP-PGPSSGCPCSLPHS-ESSLSRLLRALLAARSSLELCLFAFSSPQLGRAVQLLHQRGVRVRVITDCDYMALNGSQIGLLRKAGIQVRHDQD-LGYMHHKFAIVD--------------------KKVLITGSLNWTTQAIQNNRENVLIMEDTEYVRLFLEEFERIWEEFDPTKYSFFP-QKHRGH---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SWZ9-1", "uniprot_id": "PLD6_MOUSE", "id": "Q5SWZ9-1", "name": "Mitochondrial cardiolipin hydrolase", "aln": "------MGRSSWRLVFAAG----AGLALALEALPWLMRWLLAGRR---PRREVLFFPSQ-VTCTEALLQAPGLP-PGPS-GCPCSLPHS-ESSLSRLLRALLAARSSLELCLFAFSSPQLGRAVQLLHQRGVRVRVITDCDYMALNGSQIGLLRKAGIQVRHDQD-LGYMHHKFAIVD--------------------KKVLITGSLNWTTQAIQNNRENVLIMEDTEYVRLFLEEFERIWEEFDPTKYSFFP-QKHRGH---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N2A8-1", "uniprot_id": "PLD6_HUMAN", "id": "Q8N2A8-1", "name": "Mitochondrial cardiolipin hydrolase", "aln": "------MGRLSWQVAAAAA----VGLALTLEALPWVLRWLRSRRRR--PRREALFFPSQ-VTCTEALLRAPGAELAELPEGCPCGLPHG-ESALSRLLRALLAARASLDLCLFAFSSPQLGRAVQLLHQRGVRVRVVTDCDYMALNGSQIGLLRKAGIQVRHDQD-PGYMHHKFAIVD--------------------KRVLITGSLNWTTQAIQNNRENVLITEDDEYVRLFLEEFERIWEQFNPTKYTFFPPKKSHGSCAPPVSRAGGRLLSWHRTCGTSSESQT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KNW0-1", "uniprot_id": "PLD6_DANRE", "id": "A3KNW0-1", "name": "Mitochondrial cardiolipin hydrolase", "aln": "---MDVFKQMSFKELMKVLGLGTVAFVLGVEWLNWLTRRLRDSRG---PLKEVLFFPSP-QVCVEHLFTS------HRSFPCACPFPHGIQTSFSRLLEHLLSARTSLEMCIFSFSNMEMSRAILLLHKRGVVVRVVTDRDYMTITGSQIGALRKAGISVRHEMSSAVHMHHKFALVD--------------------GRKLISGSLNWTLTAVQSNKENVIITEEPELVRPFQQEFLKLWEASDPANLKLQSKNGQIKK---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKD7-1", "uniprot_id": "ZUC_DROME", "id": "Q9VKD7-1", "name": "Mitochondrial cardiolipin hydrolase", "aln": "MLITQIIMKQIRDYPIVSTISIAVSTVLASEVIWKLVQCSRSKREKASRVHEVIIFNELGEICAAVHMRNSSMG-SQKPQVSPCCNTHCSLRNVAKIVEQIDRAVYSIDLAIYTFTSLFLADSIKRALQRGVIIRIISDGEMVYSKGSQISMLAQLGVPVRVPIT-TNLMHNKFCIIDGFERVEEIRLLRKLKFMRPCYSIVISGSVNWTALGLGGNWENCIITADDKLTATFQAEFQRMWRAFAKTEGSQIQLK--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .. .* * : : : * :*.::* . *. : . ..* .* .::::. : * *:::.:::*:. :. :: :*** :*:::* : : .****. * : *: ** **:**.::* :*:**:*** .: .* ** :* : : . * ** ::*. :: . : ", "identical_positions": 43, "similar_positions": 71, "identity": "14.98%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3827", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60228-1", "uniprot_id": "EIF3E_HUMAN", "id": "P60228-1", "name": "Eukaryotic translation initiation factor 3 subunit E", "aln": "MAEYDLTTRIAHFLDRHLVFPLLEFLSVKEIYNEKELLQGKLDLLSDTNMVDFAMDVYKNLYSD-DIPHALREKRTTVVAQLKQLQAETEPIVKMFEDPETTRQMQSTRDGRMLFDYLADKHGFRQEYLDTLYRYAKFQYECGNYSGAAEYLYFFRVLVPATDRNALSSLWGKLASEILMQNWDAAMEDLTRLKETIDNNSVSSPLQSLQQRTWLIHWSLFVFFNHPKGRDNIIDLFLYQPQYLNAIQTMCPHILRYLTTAVITNKDVRKRRQVLKDLVKVIQQESYTYKDPITEFVECLYVNFDFDGAQKKLRECESVLVNDFFLVACLEDFIENARLFIFETFCRIHQCISINMLADKLNMTPEEAERWIVNLIRNARLDAKIDSKLGHVVMGNNAVSPYQQVIEKTKSLSFRSQMLAMNIEKKLNQNSRSEAPNWATQDSGFY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60229-1", "uniprot_id": "EIF3E_MOUSE", "id": "P60229-1", "name": "Eukaryotic translation initiation factor 3 subunit E", "aln": "MAEYDLTTRIAHFLDRHLVFPLLEFLSVKEIYNEKELLQGKLDLLSDTNMVDFAMDVYKNLYSD-DIPHALREKRTTVVAQLKQLQAETEPIVKMFEDPETTRQMQSTRDGRMLFDYLADKHGFRQEYLDTLYRYAKFQYECGNYSGAAEYLYFFRVLVPATDRNALSSLWGKLASEILMQNWDAAMEDLTRLKETIDNNSVSSPLQSLQQRTWLIHWSLFVFFNHPKGRDNIIDLFLYQPQYLNAIQTMCPHILRYLTTAVITNKDVRKRRQVLKDLVKVIQQESYTYKDPITEFVECLYVNFDFDGAQKKLRECESVLVNDFFLVACLEDFIENARLFIFETFCRIHQCISINMLADKLNMTPEEAERWIVNLIRNARLDAKIDSKLGHVVMGNNAVSPYQQVIEKTKSLSFRSQMLAMNIEKKLNQNSRSEAPNWATQDSGFY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q641X8-1", "uniprot_id": "EIF3E_RAT", "id": "Q641X8-1", "name": "Eukaryotic translation initiation factor 3 subunit E", "aln": "MAEYDLTTRIAHFLDRHLVFPLLEFLSVKEIYNEKELLQGKLDLLSDTNMVDFAMDVYKNLYSD-DIPHALREKRTTVVAQLKQLQAETEPIVKMFEDPETTRQMQSTRDGRMLFDYLADKHGFRQEYLDTLYRYAKFQYECGNYSGAAEYLYFFRVLVPATDRNALSSLWGKLASEILMQNWDAAMEDLTRLKETIDNNSVSSPLQSLQQRTWLIHWSLFVFFNHPKGRDNIIDLFLYQPQYLNAIQTMCPHILRYLTTAVITNKDVRKRRQVLKDLVKVIQQESYTYKDPITEFVECLYVNFDFDGAQKKLRECESVLVNDFFLVACLEDFIENARLFIFETFCRIHQCISINMLADKLNMTPEEAERWIVNLIRNARLDAKIDSKLGHVVMGNNAVSPYQQVIEKTKSLSFRSQMLAMNIEKKLNQNSRSEAPNWATQDSGFY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DRI1-1", "uniprot_id": "EI3EA_DANRE", "id": "Q6DRI1-1", "name": "Eukaryotic translation initiation factor 3 subunit E-A", "aln": "MAEYDLTTKIAHFLDRHLVFPLLEFLSVKEIYNEHELLHGKLDLLSDTNMVDFAMDVYRNLFPDKEIPNSLREKRTTVVAQLKQLQSETEPIVKVFEDPETTRQMQSTRDGRMLFDYLADKHGFRQEYLDTLYRYAKFQYECGNYSGAAEYLYFFRVLVPATDRNALNSLWGKLASEILMQNWEAAMEDLTRLRETIDNNTVSSPLQSLQQRTWLIHWSLFVFFNHPKGRDNIIELFLYQPQYLNAIQTMCPHILRYLTTAVITNKDVRKRRQVLKDLVKVIQQESYTYKDPITEFVECLYVNFDFDSAQKKLRECEAVLVNDFFLVACLEDFIENARLFIFETFCRIHQCISIGMLADKLNMTPEEAERWIVNLIRNARLDAKIDSKLGHVVMGNNAISPYQQVIEKTKSLSFRSQMLAMNIEKKQSNANRNETPNWAAQDAGFY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O77410-1", "uniprot_id": "EIF3E_DROME", "id": "O77410-1", "name": "Eukaryotic translation initiation factor 3 subunit E", "aln": "MANFDLTRINCQFLDRHLTFPLLEFLCGKEIYNQQELLEYILETVNKTNMIDYTMDTRKRLNLSQEMPEELVQRKAEVLATLKQLQNEVAPIMKAT---DILKNGESMKDSKTFVNALQKDYNFKVEHLESAYKLAKYLYECGNYQESTSYLYFCLIVMSPNDKNYLNVLWGKLAAEILTLNWNTALEDLTRLRDYIDNANFST-IQALQQRTWLIHWSVLVFFNHPKGRDLIIEMFLYKPLYLNAIQTMCPHIMRYLATAVVIN---RTRRNALKDLIKVIQQESYTYRDPITEFLECLYVNFDFEGARLKLHECQTVILNDFFIVACLNEFVEDARLMIFETFCRIHQCITISMLADKLNMKPNEAECWIVNLIRNARLNAKIDSKLGHVVMGTQPLSPYQQLVEKIDSLSMRSEHLAGLIERKSKQKQNQES----ADSWKYY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::*** .:******.*******. *****::***. *: :..***:*::**. :.* . ::*. * :::: *:* ***** *. **:* : :: :* :*.: :.: * ..:.*: *:*:: *: **: ******. ::.**** :::...*:* *. ******:*** **::*:******:: *** ..*: :*:***********::********** **::***:* ************:***:***: * *.**:.****:**********:******:*********:.*: **:**::*::****:****::*:*:***:************:*.********.*:*** ***********:*************.:.:*****::** .***:**: ** **:* .: ...*: ::. :*", "identical_positions": 257, "similar_positions": 126, "identity": "57.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-383", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P00884-1", "uniprot_id": "ALDOB_RAT", "id": "P00884-1", "name": "Fructose-bisphosphate aldolase B", "aln": "MAHRFPALTSEQKKELSEIAQRIVANGKGILAADESVGTMGNRLQRIKVENTEENRRQFRELLFSVDNSISQSIGGVILFHETLYQKDSQGKLFRNILKEKGIVVGIKLDQGGAPLAGTNKETTIQGLDGLSERCAQYKKDGVDFGKWRAVLRISDQCPSSLAIQENANALARYASICQQNGLVPIVEPEVLPDGDHDLEHCQYVSEKVLAAVYKALNDHHVYLEGTLLKPNMLTAGHACTKKYTPEQVAMATVTALHRTVPAAVPSICFLSGGMSEEDATLNLNAIYRCPLPRPWKLSFSYGRALQASALAAWGGKAANKKATQEAFMKRAVANCQAAQGQYVHTGSSGAASTQSLFTASYTY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91Y97-1", "uniprot_id": "ALDOB_MOUSE", "id": "Q91Y97-1", "name": "Fructose-bisphosphate aldolase B", "aln": "MAHRFPALTPEQKKELSEIAQRIVANGKGILAADESVGTMGNRLQRIKVENTEENRRQFRELLFSVDNSISQSIGGVILFHETLYQKDSQGNLFRNVLKEKGIVVGIKLDQGGAPLAGTNKETTIQGLDGLSERCAQYKKDGVDFGKWRAVLRIADQCPSSLAIQENANALARYASICQQNGLVPIVEPEVLPDGDHDLEHCQYVSEKVLAAVYKALNDHHVYLEGTLLKPNMVTAGHACTKKYTPEQVAMATVTALHRTVPAAVPGICFLSGGMSEEDATLNLNAINRCPLPRPWKLSFSYGRALQASALAAWGGKAANKKATQEAFMKRAMANCQAAQGQYVHTGSSGAAATQSLFTASYTY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05062-1", "uniprot_id": "ALDOB_HUMAN", "id": "P05062-1", "name": "Fructose-bisphosphate aldolase B", "aln": "MAHRFPALTQEQKKELSEIAQSIVANGKGILAADESVGTMGNRLQRIKVENTEENRRQFREILFSVDSSINQSIGGVILFHETLYQKDSQGKLFRNILKEKGIVVGIKLDQGGAPLAGTNKETTIQGLDGLSERCAQYKKDGVDFGKWRAVLRIADQCPSSLAIQENANALARYASICQQNGLVPIVEPEVIPDGDHDLEHCQYVTEKVLAAVYKALNDHHVYLEGTLLKPNMVTAGHACTKKYTPEQVAMATVTALHRTVPAAVPGICFLSGGMSEEDATLNLNAINLCPLPKPWKLSFSYGRALQASALAAWGGKAANKEATQEAFMKRAMANCQAAKGQYVHTGSSGAASTQSLFTACYTY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JH71-1", "uniprot_id": "ALDOB_DANRE", "id": "Q8JH71-1", "name": "Fructose-bisphosphate aldolase B", "aln": "MTHQFPALSTEQKKELATIAERIVAPGKGILAADESTGTMAKRFQKINVENTEENRRSFRDLLFSVDDSISESIGGVILFHETLYQKSDKGVLFPKVIKDKGIVVGIKVDKGTAGLAGTDGETTTQGLDGLSERCAQYKKDGCDFAKWRCVLKISDSCPSALGIAENANVLARYASICQQNGLVPIVEPEILPDGDHDLKQCQYATEKVLAAVYKALSDHHVYLEGTLLKPNMVTAGHSCTKKYTPLEVAMATVTALRRTVPAAVPGICFLSGGQSEEEASLNLNAMNQLSLHRPWKLSFSYGRALQASALSAWKGQAANKKASQDAFVTRAKINSLASKGEYKPSGQAGQASTQSLFTASYTY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07764-1", "uniprot_id": "ALF_DROME", "id": "P07764-1", "name": "Fructose-bisphosphate aldolase", "aln": "MTTYFNYPSKELQDELREIAQKIVAPGKGILAADESGPTMGKRLQDIGVENTEDNRRAYRQLLFSTDPKLAENISGVILFHETLYQKADDGTPFAEILKKKGIILGIKVDKGVVPLFGSEDEVTTQGLDDLAARCAQYKKDGCDFAKWRCVLKIGKNTPSYQSILENANVLARYASICQSQRIVPIVEPEVLPDGDHDLDRAQKVTETVLAAVYKALSDHHVYLEGTLLKPNMVTAG-QSAKKNTPEEIALATVQALRRTVPAAVTGVTFLSGGQSEEEATVNLSAINNVPLIRPWALTFSYGRALQASVLRAWAGKKENIAAGQNELLKRAKANGDAAQGKYVAGSAGAGSGSLFVANHAY--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBF5-1", "uniprot_id": "Q9VBF5_DROME", "id": "Q9VBF5-1", "name": "Fructose-bisphosphate aldolase", "aln": "MTTHFYYPNKELQEELICISKALVAPGKGILAADESSAVMGKRFQLIGVENTEENRRLYRQMLFTTDPKIAENISGVIFYHETLHQRTDDGLPFVEALRKKGILTGIKVDKHFSPLFGSEDEFTTQGLDDLANRCAQYKKEGCSFAKWRCILKITKNTPSPQAILENANVMARYAAICQSQRLVPIISPEVLATGDHDLDRCQKVNEILLAGVYKALSDHHVFLEGTLLQPSMVMPGLQSNKNHPPADIGVATVLAIRRSVPPAVMGVLFCGGAQSEEEATVHLNAINNVPLCKPWAMTFAFDRALQTSILRTWGGKKEQISHAQNELIKRCRANGLASIGKYVIGSVESSAATERLIQEAVEF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * . * :.** *:: :** ********** .*.:*:* * *****:*** :*::**:.* .: :.*.***::****:*: ..* * : ::.***: ***:*: * *:: * * ****.*: *******:* .*.***.:*:* .. ** .* ****.:****:***.: :***:.**::. *****.:.* ..* :**.*****.****:******:*.*: .* . *: .* ::.:*** *::*:**.** .: * .*. ***:*:::*.*: .* :** ::*::.****:* * :* *: : *: ::.*. * *: *:* . . :.: : . ", "identical_positions": 158, "similar_positions": 118, "identity": "43.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3831", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C7V3-1", "uniprot_id": "UTP15_MOUSE", "id": "Q8C7V3-1", "name": "U3 small nucleolar RNA-associated protein 15 homolog", "aln": "-MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQLPYNYAVTASSRIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDING-RAPLRQFEGHTKAVHTVDFTADNYHVVSGA-DDYTVKLWDIPNSKEILTFKE-HSDYVRCGCASKLNPDLFVTGSYDHTVKIFDART-NKNVL-CVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSG-----QRLLSGSLDRKVKVYST-TSYKVVHSFDYAASILSLALSH----QDETIVVGMTNGILSVKHRKSEAKKTSLPRRRR------PAYRTFIKGK--NYLKQRDDIMVSRPAK--KHLEGYDKDLKSFRVSQALDRVLEPKCVIRTPEVTVSIIKELTRRGVLANALAGRDEKEVTRVLNFLIRNLSQPRFAPVLINAAEIIIDIYLP-VIGQSSVVDKKFIVLQELVEKEIDYQRELLETLGMMDMLFATMTRNDSDPVPEHVPAELPEEKTESPTQPSDTDKNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2RRU3-1", "uniprot_id": "UTP15_RAT", "id": "A2RRU3-1", "name": "U3 small nucleolar RNA-associated protein 15 homolog", "aln": "-MAGYKPVVIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISG-RAPLRQFEGHTKAVHTVDFTADKYHVVSGA-DDYTVKLWDIPNSKEILTFKE-HSDYVRCGCASKLNPDLFVTGSYDHTVKMFDART-NKNVL-CVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSG-----QRLLSGSLDRKVKIYST-TSYKVVHSFDYAASILSLALSH----QDETVVVGMTNGILSVKHRKSEAKKESLPRRRR------PAYRTFIKGK--IYTKQRDDIVVTRPAK--KHLEWYDRDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIIIDIYLP-VIGQSSVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMTRNGSAPVWEHVPAELPEEKTESPRQPSDTDKNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TED0-1", "uniprot_id": "UTP15_HUMAN", "id": "Q8TED0-1", "name": "U3 small nucleolar RNA-associated protein 15 homolog", "aln": "-MAGYKPVAIQTYPILGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGRLLVAGSEDGGVQLFDISG-RAPLRQFEGHTKAVHTVDFTADKYHVVSGA-DDYTVKLWDIPNSKEILTFKE-HSDYVRCGCASKLNPDLFITGSYDHTVKMFDART-SESVL-SVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSG-----QRLLSGSLDRKVKVYST-TSYKVVHSFDYAASILSLALAH----EDETIVVGMTNGILSVKHRKSEAKKESLPRRRR------PAYRTFIKGK--NYMKQRDDILINRPAK--KHLELYDRDLKHFRISKALDRVLDPTCTIKTPEITVSIIKELNRRGVLANALAGRDEKEISHVLNFLIRNLSQPRFAPVLINAAEIIIDIYLP-VIGQSPVVDKKFLLLQGLVEKEIDYQRELLETLGMMDMLFATMRRKEGTSVLEHTSDGFPENKKIES----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZW33-1", "uniprot_id": "UTP15_DANRE", "id": "Q7ZW33-1", "name": "U3 small nucleolar RNA-associated protein 15 homolog", "aln": "-MASFKPTKVLSYPKLGEKVTEETLYWKNYKPPVQIKEFGAVSKIDFSPLPPHNYAVTASTRVHIYGLHSQEPIRNFTRFHDTAYGGSFRGDGKLLVAGSEEGLIRLFDIGG-RVSLRQFKGHSKAVHATSFLSDGFRVLSGS-DDLTCRVWDVASAVELSSITE-HTDYIRAIAPSKLNPDVFVTGSYDHTVKMFDVRS-GNSVM-TMQHGQPVECVLLYPSEALLVSTGGRYVKVWDLLKGGQQLVSLKNHHKTVTCACLSSS------NKLLTASLDRHVKVYN--SSYKVVHNFDCASSILSLAVAP----DDEAVAVGMTNGVLSIRHRKHKEEKEALTGRRKRG----PSYRFFVKGK--NFVPRQDDFLVSKPVR--QHLQKYDKQLKRFEVSKALDTALETWTRTTKPEVTVAVIMELNRRGTLKNALAGRDEVSLTKILNFLLKHITDPRFSRPLLTVGDIVLDLYQQ-VIPQSPVVERLLQRLYEILGREAELQQELLQVLGILDTLFASLMPRKEVASFGAAAAAQESQLQAA-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4Z9-1", "uniprot_id": "Q9W4Z9_DROME", "id": "Q9W4Z9-1", "name": "U3 small nucleolar RNA-associated protein 15 homolog", "aln": "MQNSFLPLNTRRFRQRAQVETPDTVYWDRLAKPELLKEHNTIDYLDFSPSDPDNFVVTCSVRVQIYNLVTMLVVKNLSRFQKTAYGATFRQDGRLLAAGDEEGHVKLFDTTS-RNILRLFKGHTAPVHRTFFTADKLQLASFG-DDKSVRLWDVANEKVVQTYEDTHTDYVRAGAMHPQAGHMFVSGGYDGKIKLYDTRA-ETAVQRTLDHGAPVESMLFLPNGSIFVSAGGSQVRVWDLISGCRLLTMMSQHHKTVTCLRLGSDG-----RRLLSGGLDRHVKIYDV-STYKTVHTLTYPNAVVSMAVAD----GDQAVVAGMVDGLVSIRRMMVDSKPSHLKKIRAD-----RARKYFVSTKRTNNTQEVDHTIKDHVKG--PGLKSYDVHLRQFNHKKALDDVMNAQKMQYQPELIVAVITDLLHRGSLGKALTGRHEAALVRFIDFICNHLGEVRFMRPLMMAASTVLDVFEQRLVAYSQKLMKALQRLSLAMQEEVRLTAELMRMKGAVDMLIGISMDNSEVAHKPTYVETKTPKMHPSVAAQNYVVLVE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04305-1", "uniprot_id": "UTP15_YEAST", "id": "Q04305-1", "name": "U3 small nucleolar RNA-associated protein 15", "aln": "MSTARPRIITSKAPLLPQQTTPEQRYWRQYTSAQLVKEHNSVTHISFNPQHPHDFAVTSSTRVQIFSSRTRQVIKTFSRFKDVVYSASFRSDGKLLCAGDATGLVSVYDSYNPRTILLSINASTHPTHVTKFHTQDNKILATASDDRVTRLWDISNAYEPQLELTGATDYVRTLSFIPAAPHLVATGSYDGLIRLYDTRSSGSTPIYSLNHDQPVENVIAVSP-TQIVSCGGNNFKVWDLTSN-KKLYERGNFNKAVTCLDYVENFDSPMQSALIASSLDGHVKVFDPLDNFQVKFGWKFSGPVLSCAVSPSTAQGNRHLVAGLSSGLLAIRTKKKEKRSSDKENAPASFNKNAKSNNFQRMMRGSEYQGDQEHIIHNDKVRSQRRMRAFERNINQFKWSEALDNAFVPG---MAKELTLTVLQELRKRGKVRVALYGRDESTLEPLLNWCLKGIEDVRSASIVADWVAVVLELYGN-TLESSPVLQELMIDLKTKVRHEIHKSKEAQRIEGMLQLLTS------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * : ** . . :**..:: :.*.* * ::.**.* *::*:. : ::.::**:...* .:** **:** **. * : ::* . * * ::. : ..* . * :: :: : . ** ::**:.. :**:* . .:. :*.** ::::*.*: ::*. *** :: . :** ** .:***: .. : * :.:*:*** .. *::..** :**::. .::. . . .::* *:: :. :..*: .*::::: . . : . : :. : :. :: .:. *. .:*** .: . *: :::: :* :** : ** **.* : .::: . : : * : ::::: : * : . : * : .* * . * :: * . ", "identical_positions": 87, "similar_positions": 175, "identity": "15.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3856", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q769K2-1", "uniprot_id": "NAPEP_RAT", "id": "Q769K2-1", "name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D", "aln": "-----------------------------------------MDENENSQSPAPSHQYPKETLRKRQNSVQNSGGSESSRLSRKSFKLDYRLEED----------VTKSKKGKDGRFVNPWPTWKNVSIPNVLR---WLIMEKDHSSVPGSKEELDKELPVLKP---------------------------YFISDPEEAGVREAGLRVTWLGHATLMVEMDELILLTDPMFSSRASPSQYMGPKRFRRPPCTISELPPIDAVLISHNHYDHLDYGSVLALNERFGSELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPG-HDKVTFVFTPSQHWCKRTLLDDNKVLWGSWSVLGPWN-RFFFAGDTGYCP-AFEEIGKRFGP-FDLAAIPIGAYEPRWFMKYQHADPEDAVRIHIDVQAKRSVAIHWGTFALANEHYLEPPVKLNEALERYGLKSEDFFILKHGESRYLNTDDKAFEET", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH82-1", "uniprot_id": "NAPEP_MOUSE", "id": "Q8BH82-1", "name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D", "aln": "-----------------------------------------MDEYEDSQSPAPSYQYPKETLRKRQNSVQNSGGSVSSRFSRKSFKLDYRLEED----------VTKSKKGKDGRFVNPWPTWKNISIPNVLR---WLIMEKNHSGVPGSKEELDKELPVLKP---------------------------YFVSDPEDAGVREAGLRVTWLGHATLMVEMDELIFLTDPMFSSRASPSQYMGPKRFRRPPCTISELPTIDAVLISHNHYDHLDYGSVLALNERFGSELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPG-HDKVTFVFTPSQHWCKRTLLDDNKVLWGSWSVLGPWS-RFFFAGDTGYCP-AFEEIGKRFGP-FDLAAIPIGAYEPRWFMKYQHADPEDAVRIHIDLQTKRSVAIHWGTFALANEHYLEPPVKLNEALERYGLSCEDFFILKHGESRYLNTDDRAFEET", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IQ20-1", "uniprot_id": "NAPEP_HUMAN", "id": "Q6IQ20-1", "name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D", "aln": "-----------------------------------------MDENESNQSLMTSSQYPKEAVRKRQNSARNSGASDSSRFSRKSFKLDYRLEED----------VTKSKKGKDGRFVNPWPTWKNPSIPNVLR---WLIMEKDHSSVPSSKEELDKELPVLKP---------------------------YFITNPEEAGVREAGLRVTWLGHATVMVEMDELIFLTDPIFSSRASPSQYMGPKRFRRSPCTISELPPIDAVLISHNHYDHLDYNSVIALNERFGNELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPG-HDKVTFVFTPSQHWCKRTLMDDNKVLWGSWSVLGPWN-RFFFAGDTGYCP-AFEEIGKRFGP-FDLAAIPIGAYEPRWFMKYQHVDPEEAVRIHTDVQTKKSMAIHWGTFALANEHYLEPPVKLNEALERYGLNAEDFFVLKHGESRYLNNDDENF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8RJ40-1", "uniprot_id": "A0A2R8RJ40_DANRE", "id": "A0A2R8RJ40-1", "name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D", "aln": "-----------------------------------------MAEQP------------------------LVGASSST-------PLDYRQEAD----------VTCSRRDSQGRFVNPWSTWHFPSYTTVAR---LFLTEKNNSKIPSAKEALDRELPIVQP---------------------------YFIQNPDQCGQTGTSVRATWLGHATVLVEMEGLLVLTDPIFSQRASPVAFMGPKRYRDPPCTIEQLPRLDAVVISHTHYDHLDAASVTALNSRFGSALHWFVPLGLAEWMQKTGCENVTELDWWVGSRIPG-HDNVSFFCTPAQHWCKRTPVDDNKTLWGSWSIVGSHS-RFFFAGDTGYCA-SFKEIGRHFGP-FDLAAIPIGAYVPRGIMKSQHVDPEEAVQIHIDVQAKASLAIHWGTFPLSYEHYLEPPARLREAMVNLGLNPDDFFTLHHGESRMINLKDMHSSS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02883-1", "uniprot_id": "FMP30_YEAST", "id": "Q02883-1", "name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D, mitochondrial", "aln": "MNFVTCHVQMRLLLQRRLVRLRESELFRPQTSLSTFKRHASQKTRPIQKCSRKYARILLLSVLVPYTGYAFYVSLATVKQIDLRNEMCQRLEENNNEVTYKGSLLKYSPLEVLGRFENPFEEYRIQTVFEFFANRVFELFERNRGGIPRDVHQMNKLMPVHKPTWGPNLVDVDPAEETALPLECKVLDELHIPTAVEENEGSKCPVYNTWLGQSCNYTVYNGLRILTDPLFSD-FLIHKTLGPKRITQMPSQITEVPKPDIILVSHNHPDHLDLESLEYWSGKD--SPLWIVPKGMKSYMTSNGCDNVLELSWWETLQVKKNNEIYHISATPAMHWSGRSLLDTNKSLWCSFLLTHHGNPILFHAGDTGYVKDLFVRIKERFGKGCKLALLPCGQYCPEWHQKPRHINPQEVLKIMKDLEARNVLGVHWGTFVLSGEYFLEPKEKL-EMLAEWGGFKDRCYCPELGKTECFD---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : * * : :. * *** **: :: : . : *::.. :* . ::: :*: :* :: :: : ****:: . : * .****:**. :**** *. * ::* * :::**.* **** *: . : *:** *: .:* . **:** **.** : :: : **: **. *: :* ** ** *: : . :*.****** * .* .:** .** :* * * *. * :* :*::.::* *:::: :.:***** *: *::*** :* * : . * : : . *::. :: ", "identical_positions": 99, "similar_positions": 101, "identity": "20.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3869", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZS39-1", "uniprot_id": "D3ZS39_RAT", "id": "D3ZS39-1", "name": "Protein MMS22-like", "aln": "MD---GGSAASTFLTDSLELELGTEWCKPPCFSCAFDS-RDG--KFSGESYLASGALKRLILN-----LDPLPTNFEEDTVELFGIQWVTETALVHSCR-ELFHLFRQQIFNLESLLQVN-CDFGKIAALHAKADSIRQQCVVFLHYLKVFIFRWLKVQEAESHSLLVHPYEVLEAQLPSMLVDELHGLLLYIGHLAELPSVTLGAFVNQNQIKLFPPSWHLLHLFLDTHWLVLEILHMLGEKLK-QVVYGRQFISQAGDSLTNVSLFEEHCEHLFCDLICLSLNRYDKVMPSEALMISHYPCSCVKELWVLLIHLLDHRSKWSAAESFWNWLNKLLRTLFEKSSEQRRP-VSITHAKDPLGFSWWISVHVASLFQIDRHGVLDEMRQ--MESNWSFVEELLKQSVTVQDGILEEQLRMHLHCCLTLCDFWEPNLSVVTILWEYYCKNLNSSFSISWLPLKGLTNIIKSPLSMLTLVKNCYC-----DKQDPDLYKSSSSYIIFLCILAKVVKKAMKNSGSHPWKQVKGRIYSKFHQRRMEELTEVGLQNFFCLFLLLAAVAE-IEDVASHVLDLLRFLRP-ASMSSHGTLVWKGQMAFLLMYAQKNLDIGVWAEKLSCEFQEKAKEFLVSKHDEMVQRHDLWTQLSIYIDGVQEVFETSSCLCPSHEHLLNDGFSMLLRACRESELRTVLSFLQAVLARIRSIRQQLCQELQRENVDRILQSSLSAKERPLAAVAGALWRHFFSFLKSQRMTQVVPLSQLADAAADFTLLAVDMPNTAPPDLQPQPVISIMQLFGWDDIIWPQVVARYLSHLLQNSTVCEALSQ-SSCVSFQSLTIRSWVRCVLQMYVKHLSEPD-LLIDMNPDQVMEKEYMEQLTEMTRLLFTLSEVKNIFSKAQIEYLPNPEDPKQALIQFLEAVGVTYRTLQTFSDKSAMVTKSLEYLGEILKYIKPYLGKKVSSAGLQLTYGIMGILVKSWAQIFATSKAQKLLFRIIDCLLLPHTVLQQDKELPVPMLTAIQKTLPLYLQGICAVCCQSQNPNAYLNQLLRNVIEQYIGRFLPASPSVSDLGQHPVLLALRSPASVPWMMPLRKHIVHAIRKSYLEFKGSSPPPRLASVLAFILQLFK-DTTLGVCDLELLLP----GVLKCLVLVNEPQVKRLATENLQCMVKTCQVGSEGGPATQLTS-LFRQFIQDYGMQYSYQVYSILETVAALSQHIGIQLIPTLTQSLKDSELKWGLGKNIAQREAYSKLLSRLGQAGQDEKQRLESDKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AUR6-1", "uniprot_id": "MMS22_MOUSE", "id": "B1AUR6-1", "name": "Protein MMS22-like", "aln": "MD---GCSAASTFLTDSLELELGTEWCKPPCFSCAFDN-REG--KFSGESYLASGALKRLILN-----LDPLPTNFEEDTVELFGFQWVTETALVYSCR-ELFHLFRQQIFNLESLVQVS-CDFGKIATLHAKADSIRQQCVVFLHYIKVFIFRCLKVQEAESHSRPAHPYEALEAQLPSMLVDELRGLLLYIGHLAALPSVTVGAFVNQNQMKLFPPSWHLLHLYLDTHWLVLEILHILGEKLK-QVVYGRQFIGQAGDNLTNVSLFEEHCEHLFCDLICLSLNRFDKVMPSEALLISHCPCSCVKELWVLLIHLLDHRRKWSVADSFWNWLNKLLRTLFEKSSDQRRSSVSLTQAKDPLGFSWWISVHVASLYQIDRHGVSDKMKQ--MESNWSFIEELLKRSVTVQDSILEEQLRMHLHCCLTLCDFWEPNISVVTILWEYYSKNLNSSFSISWLPLKGLTNIIKSPLSMLTLVRNCCS-----DKQDPDLYKSSSSYIIFLCILAKVVKKAMRTSGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAE-IEDVASHVLDLLRFLRP-ASMSSHGALVWKGQMAFLLMYAQKNLDIGVWAEKLSCEFQEKAKEFLVSKNDEMVQRHALWTLLCIYIDGVQEVFETSSCLYPSHEHLLNDGFSMLLPACRESELRTVLNFLQAVLARIRSVHQQLCQELQRENVDLTVQSSLSAKERPLAAVAGALWRHFFSFLKSQRMTQVVPLSQLADAAADFTLLAVDMPNTAPPDLQPQPVISIIQLFGWDDIIWPQVVARYLSHLLQNSTVYEALSQ-SSCVSSQSLTIRSWVRCVLQMHIKHLSDPD-LLIDVNPEQAVEKEYMEQLAEMTRLLFTLSEVKSVFSKAQIEQLPSPDDPKQALIQFLEAVGVTYRTLQTFSDKSAMVTKSLEYLGEVLKYIKPYLGKKVSSAGLQLTYGIMGILVKSWAHIFATSKAQKLLFRIIDCLLLPHTVLQQDKELPGPMLTAIQKTLPLYLQGICIVCCQSQNPNAYLNQLLRNVIEQYIGRFLPTSPCVSDLGQHPVLLALRNPASVPSMTPLRKHTVHAIRKSYLEFKGSSPPPRLASVLAFVLQLFK-DTEMGACDLELLLP----GILKCLVLVNEPQVKKLATENLQCMVQTCQVGSEGGPATQLTS-LFRQFIQDYGMQYSYQVYSILETVATLNQHVVIQLIPTLTQSLKDSELKWGLGRNIAQREAYSRLLSGLGQVGQGEKQRLEK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZRQ5-1", "uniprot_id": "MMS22_HUMAN", "id": "Q6ZRQ5-1", "name": "Protein MMS22-like", "aln": "ME---NCSAASTFLTDSLELELGTEWCKPPYFSCAVDN-RGGGKHFSGESYLCSGALKRLILN-----LDPLPTNFEEDTLEIFGIQWVTETALVNSSR-ELFHLFRQQLYNLETLLQSS-CDFGKVSTLHCKADNIRQQCVLFLHYVKVFIFRYLKVQNAESH-VPVHPYEALEAQLPSVLIDELHGLLLYIGHLSELPSVNIGAFVNQNQIKLFPPSWHLLHLHLDIHWLVLEILYMLGEKLK-QVVYGHQFMNLASDNLTNISLFEEHCETLLCDLISLSLNRYDKVRSSESLMSDQCPCLCIKELWVLLIHLLDHRSKWFVSESFWNWLNKLLKTLLEKSSDRRRSSMPVIQSRDPLGFSWWIITHVASFYKFDRHGVPDEMRK--VESNWNFVEELLKKSISVQGVILEEQLRMYLHCCLTLCDFWEPNIAIVTILWEYYSKNLNSSFSISWLPFKGLANTMKSPLSMLEMVKTCCC-----DKQDQELYKSSSSYTIFLCILAKVVKKAMKSNGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAE-VEDVASHVLDLLNFLKP-AFVTSQRALIWKGHMAFLLMYAQKNLDIGVLAEKFSCAFREKAKEFLVSKNEEMVQRQTIWTLLSIYIDGVQEVFETSYCLYPSHEKLLNDGFSMLLRACRESELRTVLSFLQAVLARIRSMHQQLCQELQRDNVDLFVQSSLSAKERHLAAVASALWRHFFSFLKSQRMSQVVPFSQLADAAADFTLLAMDMPSTAPSDFQPQPVISIIQLFGWDDIICPQVVARYLSHVLQNSTLCEALSH-SGYVSFQALTVRSWIRCVLQMYIKNLSGPDDLLIDKNLEEAVEKEYMKQLVKLTRLLFNLSEVKSIFSKAQVEYLSISEDPKKALVRFFEAVGVTYGNVQTLSDKSAMVTKSLEYLGEVLKYIKPYLGKKVFSAGLQLTYGMMGILVKSWAQIFATSKAQKLLFRIIDCLLLPHAVLQQEKELPAPMLSAIQKSLPLYLQGMCIVCCQSQNPNAYLNQLLGNVIEQYIGRFLPASPYVSDLGQHPVLLALRNTATIPPISSLKKCIVQVIRKSYLEYKGSSPPPRLASILAFILQLFK-ETNTDIYEVELLLP----GILKCLVLVSEPQVKRLATENLQYMVKACQVGSEEEPSSQLTS-VFRQFIQDYGMRYYYQVYSILETVATLDQQVVIHLISTLTQSLKDSEQKWGLGRNIAQREAYSKLLSHLGQMGQDEMQRLENDNT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B3DIY3-1", "uniprot_id": "MMS22_DANRE", "id": "B3DIY3-1", "name": "Protein MMS22-like", "aln": "MESEFSQSLTPPVSPSALNHYGESAPSRPPCFTCAYEAGREDTGRLSSNGYISRGALKRLLLK-----LDPAPADFGGDTVDIFDFPWVTETALVESTK-LLFGLFRQKVLKLETLVQSSSHDFGQASSLHYEAEELRQQCVLFLSYIKVFIYRFLEPSQSLDE-GPVHPFKDAEAQLPSVLVEELFSITLLIGRIGNLPANVQSAFTIQHQGKLFPPSWQLLHLHLDIHWSVLEILHLLEQRMMGQVVYAHQFVNLTGETLTNISLFEDQVNNLFCDLIGLAMNKYNKVRPTETLNTHHYHCLCTKELWILLIHLLEHRSKSIHTQSFWSYINALLQTVLKGTTSGDRDPGFPVHCKDPEGFTWWLLTHLAQIGMHNRNGTAQQEKQ--LEDNWSFVIGLLKSICDPKKAAQEEQIRVVVHCCLSLSLMWGPNVSAVTTFWEYYSKNLNSSFTVPWLGVSGLGSICRTPLCLLQQAKSCCSPAPVGSSSHTQLYRTANSFHIFLRILA--LHLSQEHAGGAPWRQIKGRLYSKFHQRRMMELSDMGLLHFLLLFLVLAQCAE-LEDVASRACDLLAMLPTNSTPLALRALQWRGQLALVLLYLEKGLDVGALAEQLAVYFSQAAREFYL-KTTEPSRKLALWAPLSSYLEGVSEVFETSPNLTLSEERLLNEGFGLLLPACRQSELSSALGFLQTVLAQLRRVHQRCGQPSHSVDSPSWAPLPSVAKER-HQAVAAALWSHFFPFLCSMRLSQTPPP-QLADAAAGFTLLALDMPGSAPQNLQPHPIQSIMQSFGWDEMLHPLLVTHYLNHLLQNGELVSWVSSGQGSGSAQALCVRAWIRCVLQQYLHKSPD--------APDARAGRNLDEQLAELTRQVFRLPEVEFVLQRAGLQSAAVK-DPKAAMAVFLKAVGRSYCELQLLSERSSAVSRALEYVGDILKYIKPYLQNKSR-EGLQLAYWTIGCLVKHWSHLLATSKAQQLLFRIVDVLLLPHALLQQDTAAHTQMLSALKDSLPMFLQGLSVAVSVSHSQGAYLKQQQHSVISQYLSRFLPATPSTGAVVNHPVLLAACESTPSPQGERLRKSILHVLRENFLQFKGLAPPPRLAAVLCFLLELLKRNSDRDPALLTIPLP----SVLRCLMLVNEPQVKRLSSEVTQLIVERCTAAVGEQPCEHTTA-ILRAFVDENEGVYDQQVYNVLEVVAVLHPFTVAALIPFLTLSLRKTECKRGLGKNTSLRNGYRRLLALLGDSGQAEMISLEED--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O46089-1", "uniprot_id": "MMS22_DROME", "id": "O46089-1", "name": "Protein MMS22-like", "aln": "MDYDLFQSDDEEILATFIQATQKQETLSAQIDVDDSEEDLVDGLHLPEFNCSGRDTLKSQLCEGGFLGNGYAQLDPPRSRLDYLCFDFAPAQLAVGAVRNYLYGEACKNVQKLLTVVMGQQHLQATAASMNSGWYRVRQQVTHFYHLMLLLRG---------------------NELLPSHFLDGFR--QLLNDQLDADTWKVLYFAEHNKGNDCQAPAYHLYHGVLEWRFLDLHILYASGNDQA----------------------FLGQLERTLDDLIVCAGHHYRSKHRSELIHSSPFMCRCNKELWLLLKRLIPKWLG-ERELDFWTLFHKAMQRHKSLHFQGESNAISLAYH----ELYSWLRLGLARLDEYNSEGWYQPDHSPLTAAPESFQTASLLKQFLASQPDEQQRRVYLIQLSPLQLQLGKPDTDVLCQLWEYFHRSLNCNFSVG-TELDQLPLTCSNGSAYVDRYNKLLS-----KSHIEDLN--LSSFTMYAWMLGKTLKLLPSQGRSNQRQKLLGRIFSKFSAAKLLALNEPGIHHVIELFLCLLLCHEDLSELAPKLREMLLCLALEKLPPVRRILVAKGHMALLLLHAQHRLSMDDYVSKLLNQLATIR-------NDAEVG--------AIYVGSLQAIFNLADDFNRGEQQLLGPWLAHYVEKCGQASQDRVWQTLHNLILRLSERRAVAGN---------------------ASGIKEALQQHIMPLVRTQYVS--SHSSWLPKLAANFIALENNGD------------KLLLGFLQGPEPINMAASAQLLLQVLED-----------GGRPASSTILQVWVKSLVLLNAQ------------HESVLALMPHVTQLEEFRLLAIDPTSLE---------------GGREPLCAFFGALGRRAQQEEAAAHVRMQLSHKLHAYVNHFELWLP--PDRSRSELGSRFYSFLAIVIYNCSTLAYVRSKPSCFFHLAMVRFLLTTQLQAGVPPEGRLPQVVHKIFPVLLQGIGRLPYR---TDAYVAKTLEQLVQHWTPHFSFSSNAKLVARPYATLLQADVDG------ELAQFVLQLLVTQFLVVQRRRAGQHAGLVITIMQQLIESTGKEQEEQLLTVLRGVHIPLLEHVMFVDEVDLSRNQVFGLYKVLISHDAYKRSQAVRDMCSNHLRSLAEKHLAHCTYFYFQMLINLAELAPDLVAPILSFIREQAEQVELKRGAGEDVGIRKCLQRLQKVLSRV-------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * . . :: . : . ::. . .:** : : . : . :: : : :.. * : : *: ::: :* ::: . . :::: :*** . * : :: : *** ::: : * .:: . :: . .*:::* * *: :: *.**: : * : : : *** : ::: . :* : * * ****:** :*: : .**. :: :: . . : *: :* : : .* : :. .* * . ::: :: . : *: : :***: :.**..*:: .. * . . : .. . .. :* .*: :: :*. :: ::: **::*** :: *.: *: :.: *** * * :.::*.: ::* * * :*::*::*:: :: *.:. ..:: : . *: .:. :*: : : ..::**. :. : * ::. . *: :: :: : : .: ** *::.:: : :: *.. **.* * : :: : : : :: * ::*:: . . .: :: *::.:: : . ** :: : ..:: . : .: *: *:* : :. ::: *. : :: * .: . * :. :: : : . . . :*:: :* : ** : .::. :*: ***: .**: : .::.:: :* :: :..** * : :: : .:* : . : . :: :: :*:: : * :*. :::*.* ::.: :: . . . : :* : :. :.:* :* * ::. : . .. * * * *.: . *: :* *. ", "identical_positions": 130, "similar_positions": 360, "identity": "10.22%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3876", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96QT6-1", "uniprot_id": "PHF12_HUMAN", "id": "Q96QT6-1", "name": "PHD finger protein 12", "aln": "MWEKMETKTIVYDLDTSGGLMEQIQALLAPPKTDEAEKRSRKPEKEPRRSGRATNHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGEWMCHRCTVRRKKREQKKELGHVNGLVD-KSGKRTTSPSSDTDL----LDRSASK--TELK-AIAHARILERRAS-RPGTPTSS-ASTETPT-SEQNDVDEDIIDVDEEPVAAEP--DYVQPQLRRPFELLIAAAMERNPTQFQLPNELTCTTALPGSSKRRRKEETTGKNVKKTQHELDHNGLVPLPVKVCFTCNRSCRVAPLIQCDYCPLLFHMDCLEPPLTAMPLGRWMCPNHIEHVVLNQKNMTLSNRCQVFDRFQDTVSQHVVKVDFLNRIHKKHPPNRRVLQSVKRRSLKVPDAIKSQYQFPPPLIAPAAIRDGELICNGIPEESQMHLLNSEHLATQAEQQEWLCSVVALQCSILKHLSAKQMPSHWDSEQTEKADIKPVIVTDSSVTTSLQTADKTPTPSHYPLSCPSGISTQNSLSCSPPHQSPALEDIGCSSCAEKSKKTPCGTANGPVNTEVKANGPHLYSSPTDSTDPRRLPGANTPLPGLSHRQGWPRPLTPPAAGGLQNHTVGIIVKTENATGPSSCPQRSLVP--VPSLPPSIPSSCASIENTSTLQRKTVQSQIGPPLTDSRPLGSPPNATRVLTPPQAAGDGILATTANQRFSSPAPSSDGKVSPGTLSIGSALTVPSFPANSTAMVDLTNSLRAFMDVNGEIEINMLDEKLIKFLALQRIHQLFPSRVQPSPGSVGTHQLASGGHHIEVQRKEVQARAVFYPLLGLGGAVNMCYRTLYIGTGADMDVCLTNYGHCNYVSGKHACIFYDENTKHYELLNYSEHGTTVDNVLYSCDFSEKTPPTPPSSIVAKVQSVIRRRRHQKQDE-----EPSEEAAMMSSQAQGPQRRPCNCKASSSSLIGGSGAGWEGTALLHHGSYIKLGCLQFVFSITEFATKQPKGDASLLQDGVLAEKLSLKPHQG-PVLRSNSVP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SPL2-1", "uniprot_id": "PHF12_MOUSE", "id": "Q5SPL2-1", "name": "PHD finger protein 12", "aln": "MWEKMETKTIVYDLDTSGGLMEQIQALLAPPKTDEAEKRSRKPEKESRRSGRATNHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGEWMCHRCTVRRKKREQKKELGHVNGLVD-KSSKRTTSPSSDTDL----LDRPASK--TELK-AIAHARILERRAS-RPGTPTSN-ASTETPT-SEHNDVDEDIVDVDEEPVAAEP--DYVQPQLRRPFELLIAAAMERNPTQFQLPNELTCTTALPGSSKRRRKEETTGKNVKRTQHELDHNGLVPLPVKVCFTCNRSCRVAPLIQCDYCPLLFHMDCLEPPLTAMPLGRWMCPNHIEHVVLNQKNLTLSNRCQVFDRFQDTISQHVVKVDFLNRIHKKHPPNRRVLQSVKRRSLKVPDAIKSQYQFPPPLIAPAAIRDGELICSGVPEESQTHLLNSEHLATQAEQQEWLCSVVALQCSILKHLSAKQMPSPWDSEQTEKADIKPVIVTDSSITTSLQTADKAPLPSHYPLSCPSAVSTQNSLGCSPPHQPPTLEDISCSSCVEKSKKAPCGTANGPVNTEIKANGPHLYSSPTDSTDPRRLPGANTPLPGLTHRQGWPRPLTPPSAGGLQNH-VGIIVKTENATGPSSCPQRSLVP--VPSLPPSIPSSCASIENTSTLHRKTVQSQIGPSSTESRPLGSPPNATRVLTPPQAAGDSILATGANQRFCSPAPSSDGKVSPGTLSIGSALTVPSFPANSTAMVDLTNSLRAFMDVNGEIEINMLDEKLIKFLALQRVHQLFPSRVQASPGNVGTHPLASGGHHPEVQRKEVQARAVFCPLLGLGGAVNMCYRTLYIGTGADMDVCLTNYGHCNYVSGKHACIFYDENTKHYELLNYSEHGTTVDNVLYSCDFSEKTPPTPPSSIVAKVQSVIRRRRHQKQDE-----EPSEEAAMMSSQAQGPQRRPCNCKASSSSLIGGSGAGWEGTALLHHGSYIKLGCLQFVFSITEFATKQPKGDASLLQDGVLAEKLSLKPHQG-PVLRSNSVP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B5C8-1", "uniprot_id": "A0ACD6B5C8_DANRE", "id": "A0ACD6B5C8-1", "name": "PHD finger protein 12", "aln": "MWGKMETPTIMYDLDTSGGLMEKIQTLLAPPKSEDGEKKNRKPDRSTRRSGRATNHDICDSCREGGDLLCCDHCPAAFHLQCCNPPLSREMLPSGDWMCHRCTVRKKKREQKKEQ--INGLLERQLGKQTPPPAPEQDCGTLRLDPSVGTGGTGLRAAVAQVRLLERRHSSRPATPNSNTSSADTPTPSEQNDTEEDLLDVEDETQGSEPELSNTTTTLKRPFDLLIAAAMQRNPTQFQLPNDLTCTTALPGTSKRRRKDELSSKSVKRPQHELDSCGLVPLPVKVCYTCSRSCRLAPLIQCDFCPLLFHMDCLDPPLTAFPTGRWMCPNHIQNLILNQRSLTISNRCQLFDQFQDCISQHAVKLDFLQRIHRQHPPIQRSTHARSKKTLKVPDAIKSQYQNPPTLMASAGVREGELICTGLPEAS-----VPQHLASEDEQHQWLKDIISLQCSIMRHLRNRQT-SHWDSEHTEKTDLK---LRDS---------------------CQSAAS-QGSQNSSP--------KVPCSSCTEGLCQN-CKTTNGPVDQSIQSNG---------TQDPVRTQNKSADRE----KPCLPMPSPPNHAN------SGAIIKGEDASLKPRSGTDVLPPAHVKSEPRTQPCDHAKTPPASDAAAKVSDSTVCTGAHAVKPQ-------KVTSDAGSNGQ-----------RSPSSSCGGKSSLDSVMAGSGDISSCTEPN---MSELSGRIKDIMQGGGEVELNALDEKFIKLLAWQRIQQLFDSKSSPVQSSSPLSVSPAHRKHGEAQNREVQARASFCSVS--GNAVNMCYRSLHIGTGADMDVCLTNYGHCNYVSGKHACIFYDENTKQYELLNYSEHGTTVDNILYSCDFSEKMSQSPSSNLLTKVQNIIRRCRKKEQEDSLNSVPSAKEVTHMSCQSQDASVTPCNCKNSGSRMIGGSGAGWEGTALLHHGSHVKLGCLQFIFSIAEFANKPLKEELSACSLALTPGQQGEQLSKPNPPLQHNLVT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **** **:***********:**:******:::.**:.***::..********** ****:*************************.****.*:*********:******** :***:: : .*:*..*:.: * ** .... * *: *:*:.*:**** * **.**.*. :*::*** **:**.:**::**::*. .:** . . . *:***:*******:**********:*********:******:* :.*.**:.***** **********:**.****:*******:**********:*****:* *********::::***:.:*:*****:**:*** :***.**:***:***::*** :* :: .:::************ **.*:*.*.:*:*****.*:** * .:***:: **::** .:::*****::** :* * ****:***:*:* : ** * *. * *.* ..** .: ****.* : * *:****: .:::** : ** * . .: : * * .* *. * *:* *:*: . . * * * * * : *.. *. :* *. :* : . :* :* : . : *: **:.*..** * .:: **. .. .* * :*:. :: :*: .**:*:* ****:**:** **::*** *: .. .. .: :* *.*.:****** * .: *.*******:*:**********************************:***************:********* . :*.*.:::***.:*** *:::*:: .::*.: **.*:*... ***** *.* :******************::*******:***:***.* * : * . .: . : . : : * *: * *.", "identical_positions": 520, "similar_positions": 248, "identity": "50.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3885", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LH20-1", "uniprot_id": "A0ABK0LH20_RAT", "id": "A0ABK0LH20-1", "name": "", "aln": "MLTSYAGLSEAETWSLAVSCGTHTPENEFRGKLLTQRWTQEDKTSSCRTERHFLCRYHKMSSESDDKRARTRSKTLRGPPETTGADLSCP-TPGCTGSGHVRGKYSRHRSLQSCPLAKKRKLEDAETEHLVSKRKSHPLRLALDEG--------------YRMDSDGSEDAEVKDASVSDESE------EPLEEAEAEMSGQ-------------------EEIHHPQTAEGKS---------------------LIKPHFGSNPTSSPSGFSKGSYSSYQGIIATSLLNLG-QIAEETLVQEDSVSVAKLGPT----VVHQLQDEAAMVANSDEGEKDLFIQPEDV-----------------------------------EEVIEVTSERSQEPCPQSLKDMVNEESSKQKGVLGHEEE--EEEEEEEEEEEEEGEE---------------GEEEEEEEEEEDEEDEEEDEEEEEEEEEAASNVLFGDDTTHTSVQKASSEFRGPELSSPKPEYSVIVEVRSDDDKD----------------------------EDSHSQKSAVTDESEMYDMMTRGNLGLLEQAIALKAEQVRAVCESGCPPAEQGHLGPGEPGKMAKPLDVVR--------------KSCYNKDPSRVEKREIKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRIPPEILAMHENVLKCPTPGCTGQGHVNSNRNTHRSLSGCPIAAAEKLAKSHEKQQLQTG----DPPKNNSNSD-------RILRPMCFVKQLEVPPYGSYRPNVAPTTPRANLAKELEKFSKVTFDYASFDAQVFGKRMLAPKIQTSETSPKAFQ-----------------------------------CFDYSHDAEAAHMAATAILNLSTRCWEMPENLSTKPQDLPSKAVDIEVDENGTLDLSMHKHRKRENTFPSSSSCSSSPGVKSPDVSQR------QSSTSAPSSSMTSPQS------------------------SQASRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEADDQEVSEENFEERKYPGEVTLTNFKLKFLSKD-------IKKELLTCPTPGCDGSG------HITGNYAS-----------------HRSLSGCPLADKSLRNLMAAHSADLKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGLKVAPTKDDKEDPELMKCPVPGCVGLGHISGKYASHRSASGCPLAAR-------------RQKEGALNGSSFSWKSLKNEG----------------PTCPTPG------CDGSGHANGSFLTHRSLSGCPRATFAGKKGKLSGDEILSPKFKTSDVLEN----------DEEIKQLNQEIRDLNESNLEMEAAMVQLQSQISSMEKNLKNIEEENKLIE------EQNEALFLELSG------------------------------------------------------------------------------LSQALIQSLANIRLPHL----------------------------------------------------------------------------------------------------------------------------EPICEQNFDAYVNTLTDMYSNQDCYQNPENKG------LLETIKQAVRGIQV---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CFC2-1", "uniprot_id": "MYT1_MOUSE", "id": "Q8CFC2-1", "name": "Myelin transcription factor 1", "aln": "-----------------------------------------------------------MSSESDDKRARTRSKTLRGPPETTGADLSCP-TPGCTGSGHVRGKYSRHRSLQSCPLAKKRKLEDAETEHLVSKRKSHPLRLALDEG--------------YRMDSDGSEDAEVKDVSVSDESE------GPLEEAEAEMSGQ-------------------EEIHHPQTAEGKS---------------------LIKPHFDSNPTSSPSGFSKSSYSSYQGIIATSLLNLG-QIAEEALVKEDSVSVAKLSPT----VVHQLQDEAAMGVNSDEGEKDLFIQPEDV-----------------------------------EEVIEVTSERSQEPCPQSLKDMVSEESSKQKGVLGHEEEGEEEEEDEEEEDEEEEEE---------------GEEGEEEEEEEEEEEEEEDEEEEEEEEEAAPNVIFGEDTSHTSVQKASPEFRGPELSSPKPEYSVIVEVRSDDDKD----------------------------EDSRSQKSAVTDESEMYDMMTRGNLGLLEQAIALKAEQVRAVCESGCPPAEQGHLGPGEPGKMAKPLDVVR--------------KSCYSKDPSRVEKREIKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRIPPEILAMHENVLKCPTPGCTGQGHVNSNRNTHRSLSGCPIAAAEKLAKSHEKQQLQTG----DPPKNNSNSD-------RILRPMCFVKQLEVPPYGSYRPNVAPATPRANLAKELEKFSKVTFDYASFDAQVFGKRMLAPKIQTSETSPKAFQ-----------------------------------CFDYSHDAEAAHMAATAILNLSTRCWEMPENLSTKPQDLPSKAVDIEVDENGTLDLSMHKHRKRENTFPSSSSCSSSPGVKSPDVSQR------QSSTSAPSSSMTSPQS------------------------SQASRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEADDQEVSEENFEERKYPGEVTLTNFKLKFLSKD-------IKKELLTCPTPGCDGSG------HITGNYAS-----------------HRSLSGCPLADKSLRNLMAAHSADLKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGLKVAPTKDDKEDPELMKCPVPGCVGLGHISGKYASHRSASGCPLAAR-------------RQKEGALNGSSFSWKSLKNEG----------------PTCPTPG------CDGSGHANGSFLTHRSLSGCPRATFAGKKGKLSGDEILSPKFKTSDVLEN----------DEEIKQLNQEIRDLNESNSEMEAAMVQLQSQISSMEKNLKNIEEENKLIE------EQNEALFLELSG------------------------------------------------------------------------------LSQALIQSLANIRLPHM----------------------------------------------------------------------------------------------------------------------------EPICEQNFDAYVNTLTDMYSNQDCYQNPENKG------LLETIKQAVRGIQV---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01538-1", "uniprot_id": "MYT1_HUMAN", "id": "Q01538-1", "name": "Myelin transcription factor 1", "aln": "-----------------------------------------------------------MSLENEDKRARTRSKALRGPPETTAADLSCP-TPGCTGSGHVRGKYSRHRSLQSCPLAKKRKLEGAEAEHLVSKRKSHPLKLALDEG--------------YGVDSDGSEDTEVKDASVSDESE------GTLEGAEAETSGQ-------------------DEIHRPETAEGRS---------------------PVKSHFGSNPIGSATASSKGSYSSYQGIIATSLLNLG-QIAEETLVEEDLGQAAKPGPG----IVHLLQ-EAAEGAASEEGEKGLFIQPEDA-----------------------------------EEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEE---------------EEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAP-ELRGPESPSPKPEYSVIVEVRSDDDKD----------------------------EDTHSRKSTVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEPGCPPAEQSQLGLGEPGKAAKPLDTVR--------------KSYYSKDPSRAEKREIKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRIPPEILAMHENVLKCPTPGCTGQGHVNSNRNTHRSLSGCPIAAAEKLAKSHEKQQPQTG----DPSKSSSNSD-------RILRPMCFVKQLEVPPYGSYRPNVAPATPRANLAKELEKFSKVTFDYASFDAQVFGKRMLAPKIQTSETSPKAFQ-----------------------------------CFDYSQDAEAAHMAATAILNLSTRCWEMPENLSTKPQDLPSKSVDIEVDENGTLDLSMHKHRKRENAFPSSSSCSSSPGVKSPDASQR------HSSTSAPSSSMTSPQS------------------------SQASRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEADDQEVSEENFEERKYPGEVTLTNFKLKFLSKD-------IKKELLTCPTPGCDGSG------HITGNYAS-----------------HRSLSGCPLADKSLRNLMAAHSADLKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGVKVAPTKDDKEDPELMKCPVPGCVGLGHISGKYASHRSASGCPLAAR-------------RQKEGSLNGSSFSWKSLKNEG----------------PTCPTPG------CDGSGHANGSFLTHRSLSGCPRATFAGKKGKLSGDEVLSPKFKTSDVLEN----------DEEIKQLNQEIRDLNESNSEMEAAMVQLQSQISSMEKNLKNIEEENKLIE------EQNEALFLELSG------------------------------------------------------------------------------LSQALIQSLANIRLPHM----------------------------------------------------------------------------------------------------------------------------EPICEQNFDAYVSTLTDMYSNQ----DPENKD------LLESIKQAVRGIQV---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AYN3-1", "uniprot_id": "A0A8M3AYN3_DANRE", "id": "A0A8M3AYN3-1", "name": "", "aln": "-----------------MKLCKTFLENEFRGQLLSQRWTRGDRVSSCESKR---SRRQKMSQDADDKRTRTRSKGIRVPLELVGQEYSCP-TPGCDGLGHVSGKYARHRSALGCPLAKKRKLQEAEENLPAPKKKPNLLKLAMDDG--------------FNADSDTNSETETKDEGVESEEDTADKVMEVKEKSPASEAMT-------------------EESSQVNLEEKET---------------------PIRQTSPVPEIEIEKEEANIESTPIQQITMDTEAEEELQVAEEIQAREEEVEEEAEEITEEERVTQQLKETDEPVTTVEEEEEDDEEDEEGE-----------------------------------EETQCLSQKNNSD--HQYFSGDFGKMQTKETGELERDSEDEDEEGDEEEEEEQSQVEP---SSLMAPVPTVSAQELDVMTHGNINLDHHLGEDEEEEEDEDERDDASDKDSPTVVIELGSDGEEEEEEEEEDDGEEEEEEIDEADDDD----------------------------LDSMSQRSEVTDDSETYD-MTRGNLGLLEQAIALKAEQTGHSSEESYSPEQQPYHSLDD--RTSKVMDIAAR-------------RAYYGKDGSRLEKKEVKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRIPPEILAMHENVLKCPTPGCTGQGHVNSNRNTHRSLSGCPIAAAGKHKSHDKQSQPQTSVI--DPASVGSNSD-------RVLRPMCFVKQLEIPQYGSYRTNAMPATPRANLAKELEKYSKVSFDYASFDVQVFGKRMLAPKMPTSETSPKAFKSI-------LIPKAPSPSHSLSGGYTKSSSSSTSSGYDYTHDAEAAHMAATAILNLSTRCWERPENLSTRPPDQAGKDMDIEVDENGTLDLSMKKP-KRE-------------GVRSPDPSS-------SSSSSSQHHGVTSPHS------------------------SHTYKQEEWEGPLDYTKSNRQKEEEPEEVEYTTHSYASSDGEDDDGTQEGAEDRTYPGEVTTSSYKVKFQPKD-------LKKEILLCPTPGCDGSG------HITGNYAS-----------------HRSLSGCPLADKSLRTLMAAHTAELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKGGIKTTPTKDDKEDSELIKCPVPGCDSLGHISGKYATHRSAYGCPLAAR-------------RQKEGMLNGTPFSWKAFKTEG----------------PTCPTPG------CDGSGHANGSFLTHRSLSGCPRASANKKRARFPGDDYISKKFRASDVLDN----------DEDIKQLNKEINELNESNSEMEADMANLHTQISSMEKNLKSMEEENKLIE------EKNEALFMELSG------------------------------------------------------------------------------LSQALIRSLANIRLPQMQ---------------------------------------------------------------------------------------------------------------------------EPITEQNFDAYVDTLTHMFTDKECYQNPENRA------LLESINQAVKGIEV---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PJ12-1", "uniprot_id": "M9PJ12_DROME", "id": "M9PJ12-1", "name": "", "aln": "--MALSKRPLTKDTPLSESNGNHTNGNDHETSIKRRKRCSRDDDSSLINNNNNNNNNNNNNNNNNSNSNNNNLPQKKRKQGGQGHIADSPESPTCGSLPTPLAKSNTDADQDDETLIRETQAALKSLSGSWPDSRGNLYRLQEQDENPPPFQNLFEEKQKYEAIGNPSHAIQAQASSPNPNSTLFSRFHRQKENDQARLNAASGAGGVVHLEAQGRGKKTPDEDQDPELEDTSSSASGQGVYTQAASAFKPPIDIIKRNYVAAAHAHYSAYNAAAAAESAAGLAYYGYAAAAAASQQQQQQQQQHQQQQHQQLSTAFDIASQLGEKQRPKEPMADGKQYTILQPAGIGSRAASVMQDIASREGVVGVPLVATPPSTAAGSPAAAVPAAGPSTPSTPAPSYSPGSQNRVLALHEQILKCPTPGCNGRGHVQPHRSVHRSLSGCPRAVRRSGGTSRRPGAAPLAAAAADLDKHEKELHPLDKLKLASNHYLNNNNSNCINNNSSKLSGSTTMPIIKSEYSPVASIKSEYNKSPMHSYLSGEAAAPAPAAPSSASAVQAPRSGSASGATAANGENNLHAPHLSRFVGLQSPPHQPHLNPHGHHQQQQQQQQQQQQQQQQQQQQQQQQQHTLHQQRGPFIEGNDVPDPSANYHSEHQQQQQQQQQQQQADERQQQYEQMRYAQSHVSVGPSGELMAPNGGELSPGTARSAYEAHPGHPHPHPGHPHPHPPVSLSSLSSPAFTVDAVTAASGAGFERYDPSGVCCPSNGQRATAATAATAAGASAAAAAYHYLPQTTDEMQAQQQKYLQEQQLMLAKAEHEELANGGQPLYPRPMYHYDPTMGPLPPGFSAINLSVKMAAAQAAAAAAAYQNQQQQQQQQQQQQQHHQQQQQQQQQQQQQQQQQHGKQSSSPAPNVSGVPAVDLSGSTSVTSSSPHGFNSPASHNQYTAQRMGNGSPQPGASPNIASPQVPSPQGQTLDLSVTRLPHSIITSPQYGADGLVVGHAQGFVSGATGPLGPGNGGPPRSPQMEPVDFSGPPRPLGFGLVGHISGPRPYSRESTPDSGGSHYIETYRDPSGYSPHPGYGMVVQSDYPPAGYHGYGPAAYQCSNPYATAVGPGGYPTPVSGGYSPSPATCYSMPPPQHIPQHDKSKDGLTGCSRSDRNHLQSHSQELKCPTPGCDGSGHVTGNYSSHRSLSGCPRANKP----KSKPRDGQDSEPLRCPIPGCDGSGHSTGKFLSHRSASGCPIANRNKMRVLEAGGTVEQHKAAVAAATAMKFDACTTVGSQGIKKPKFDEVTMVYPKGYTGGSGLDIVMGGVGSSVGVGLGLNVGIGVTSSSSSSSSAGGNNNNSGSSNTVVTDKNPSGGGASSGANGSDDLNTLEAEISELQRENARVESQMMRLKSDINAMESQLSTSDREASPLSGHQQQQQRSSVALASPSGQSPFASVSSTSGASSSVSGATTNSNNNNSSSGGGTTNANDLNHSISNLAPSSGSNPNQAIEGVGGAPPNANLNNYYESLRNNVITLLEHVRLPPPPPPPGAATPSSSASSVVHGLDNVCGAGGQLVAGGSLMGGEHATAYSTLLPPPPPPSSGGAASVGGMYGVGANGATGLHQGTGSSNGGGLGSSGAVGPPPVPPHHHPYTVHHPVSYAHPHGHPHAHPHPHEHFDSYISKLQSLCVPPDVYALPEDADRPVYNSVKPTMHQDYGKLMPTPI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :.: ... : . ..* :* * . .* . . . .* :: : . . .. : : :* :: : .: . :.: . . :. * * :* : : : : : . : :: .:: . :. * : :: : . . . . . . .. : . * : . . : . . : :.. * . :: : : .:.. : .. . . .: . :.. .: * : ...:.: :** . . : : : :* : : : . : :. : :::: : . : : : : :* * : :.*: : .. :.. . .*: * :..: :. . . :: :. **. . *: . * . .: : : * :: :*. .: : . * : * : * . * .*. .: :: : : : . . *: .. . * ... . . :* . : :: . : .: **: .. * : :***: . :. *:*:: . * .:.:: .. *. :. * .* . ..: : . .. *..* . . * ::*.*:. .:* .* . ..:* *. : :*: :*************:****:***********:* .. * :*.* ::**:*** . ** :**: :**** ***:* * ::* . .:.:.:.: .. * *. * * .* * : * * . * . :: . . .:: * : .:* . .:::: *: ** :*:..* .:*: * .*:::*.:**.:*.. :.* . :. ::... : . ** * : :* * ::*** .* .::**:*:..* : **: : :::* : ", "identical_positions": 148, "similar_positions": 362, "identity": "8.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3892", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZMJ4-1", "uniprot_id": "D3ZMJ4_RAT", "id": "D3ZMJ4-1", "name": "Ankyrin repeat domain-containing protein 13C", "aln": "MTGEKIRSLRRDHKPSKEDGDVLEPCEEEATAALGGAFTGGRSGAGGSGKGGKACHKIFS-HHHRLQLKAPTAPG--PGVPAPPQHN-AVTATCPAPACLG-SNP-VVVADGGSCPSLYPVHECVFKGDVRRLSS--LIRTHN--IGQKDNHGNTPLHLAVMLGNKECAHLLLAHNAPVKVKNAQGWSPLAEAISYGDRQMITALLRKLKQQSRESVGEKRPRLLKALKELGDFYLELHWDFQSWVPLLSRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGDLSFIFSGDAAPSESFVVLDNEQKVYQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTERVG-NFLADFYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGSLTEQN---------------------------FEPVRRQSLTPPPQNTITWEEYISAENGKAPHLGRELVCKESKKTFKATVAMSQEFPLGIESLLNVLEVIAPFKHFNKLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFRC-DEFDGSIFAIPEDYKEDPSRFPDL------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UX43-1", "uniprot_id": "AN13C_MOUSE", "id": "Q3UX43-1", "name": "Ankyrin repeat domain-containing protein 13C", "aln": "MTGEKIRSLRRDHKPSKEDGDVLEPCEEEATAALGGAFTGGRSGPGGSGKGGKACHKIFS-HHHRLQLKAPAVPG--PGVPAPPQHN-AVTATCPAPACLGGSNP-ALVADGGGCPSLYPVHECVFKGDVRRLSS--LIRTHN--IGQKDNHGNTPLHLAVMLGNKECAHLLLAHNAPVKVKNAQGWSPLAEAISYGDRQMITALLRKLKQQSRESVGEKRPRLLKALKELGDFYLELHWDFQSWVPLLSRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGDLSFIFNGDAAPSESFVVLDNEQKVYQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTERVG-NFLADFYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGSLAEQS---------------------------FEPVRRQSLTPPPQNTITWEEYISAENGKAPHLGRELVCKESKKTFKATVAMSQEFPLGIESLLNVLEVIAPFKHFNKLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFRC-DEFDGSIFAIPEDYKEDPSRFPDL------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N6S4-1", "uniprot_id": "AN13C_HUMAN", "id": "Q8N6S4-1", "name": "Ankyrin repeat domain-containing protein 13C", "aln": "MTGEKIRSLRRDHKPSKEEGDLLEPGDEEAAAALGGTFTRSRIG-----KGGKACHKIFSNHHHRLQLKAAPASSNPPGAPALPLHNSSVTANSQSPALLAGTNPVAVVADGGSCPAHYPVHECVFKGDVRRLSS--LIRTHN--IGQKDNHGNTPLHLAVMLGNKECAHLLLAHNAPVKVKNAQGWSPLAEAISYGDRQMITALLRKLKQQSRESVEEKRPRLLKALKELGDFYLELHWDFQSWVPLLSRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGDLSFIFNGDAAPSESFVVLDNEQKVYQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTERVG-NFLADFYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGNIMEQN---------------------------FEPIRRQSLTPPPQNTITWEEYISAENGKAPHLGRELVCKESKKTFKATIAMSQEFPLGIELLLNVLEVVAPFKHFNKLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFRY-DEFDGSIFTIPDDYKEDPSRFPDL------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZUV0-1", "uniprot_id": "AN13C_DANRE", "id": "Q7ZUV0-1", "name": "Ankyrin repeat domain-containing protein 13C", "aln": "MTGEKIRSVRKERKSG---LDLLEP--DEEPAATG--------------PAKHRGSKIFSGGNHRIS-RSSSSPG----------------------------DP-----DG-----AYPVHECVFRGDVRRLSS--LIRTQN--IAQKDVHGNTPLHLAVMMGHKECAHLLLAHNAPVKVKNAQGWSPLAEAISYGDRQMITALLRKLKQQSRESVEDKRPRLLKALKELGDFYLELHWDFQSWVPLLSRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGDLSFIFCGDAPPSESFVVLDNEQKVYQRIHHEESEMETEEEVDILMSSDVYSATLSTKSITFSRAQTGWLFREDKTERVG-NFLADFYMVNGLVLESRKRREHLSEEDILRNKAIMESFSKGGSLIEQN---------------------------FEPMRRQSLTPPSPNTISWEEYITAETGKAPHLGRELVCKESKKNFKATVAMSPDFPLGIESLLNVLEVIAPFKHFNKLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFRY-DEFDESIFTIPSDYKGDPSRFPDL------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KFB5-1", "uniprot_id": "A0A0B4KFB5_DROME", "id": "A0A0B4KFB5-1", "name": "Ankyrin repeat domain-containing protein", "aln": "MSKEKEDECDKHKQQATADAKSTSSEDSDEYQSAGEGEDGDGDG-----DGDSPAERPPDKTSPTVAVAPTAKAA----------------------------SP-LPTVKPASEALDFPMHRSVFEDDIKSLQRRLLLSTAQDEVGRKDKHGNTPLHLAVMLGRKHAVRLLLAQNAPVKIKNNEGWSPLSEAISYGDRQTITQVLRMLKLQSREHMESRREKLVNALRQMQDFYMEFKWDFQSWLPLVSRILPSDICRLYKSGASIRLDTTLVDFNDMRWERGDISFLFRGEAPARESLVLLDNEQECFQRLRYEES--DMEDEVDVLMSTDILATQMSTKTIQFARAQRGWIFRANRKELIGGQYQCEIYTIQGLILKQRKRREHLSHEDLQKNRAIVETITKGASQQPDTRRSSLGSQHTATPPETNTPTAPNGISLPELPRRSSLQAPPPPTVTWRQYLDAEVGKCPQLGRTPVHKQSNKTLRATVAMSKDFPLSVDMLLDVLEVVAPLKHINKLREFVTLKLPTGFPVKIEIPVLHTVTAKVTFQKFEFRDNIPAKMFEVPSHYWEDVRRFQDLXPGDGEAAPKAKAATGGPTGAATGVHVDLNRNASSPSIAEFD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ** . :.:: . . .. .: : * . : . : ... .. .* . :*:*..**..*:: *. *: * : :.:** ***********:*.*...:****:*****:** :*****:********* ** :** ** **** : .:* :*::**::: ***:*::******:**:******* *::**.* .*******:**.**: :***:**:* *:*.. **:*:*****: :**:::*** : *:***:***:*: :: :***:* *:*** **:** ::.* :* :: .::* ::**:*:.********.**: :*:**:*:::**.. :. * **.** .*. *::*.:*: ** **.*:*** * *:*:*.::**:*** :***.:: **:****:**:**:******* :***.*****::***: *:**.****:*. *:: .:* :*..* * ** ** ", "identical_positions": 238, "similar_positions": 160, "identity": "38.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3893", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AGD6-1", "uniprot_id": "A0A8I6AGD6_RAT", "id": "A0A8I6AGD6-1", "name": "", "aln": "MLLLALRRARGRGRGRPAWGPRRARSPPWSPAWICCWALAGCQAVWAGDS-SSLGRPLPACQEKDYHFEYTECDSTGSRWRVAIPNSAVDCSGLPDPVRGKECTFSCASGEYLEMKNQVCSKCVEGTYSLGSGIKFDEWDELPAGFSNVATFMDTVVGPSDSRPDGCNNSSWLPRGNYIESNRDDCTVSLIYAVHLKKSGYVFFEYQYVDNNIFFEFFIQNDQCQEMDAT-TDKWVKLTDNGEWGSHSVMLKSGTNILYWRTTGILMGSKAVKPVLVKNITIEGVAYTSECFPCKPGTFSNKPGSFNCQMCPRNTYSEKGAKECIRCKEDSQFSEEGASECVDRPPCTTKDYFQIHTPCDEEGKTQIMYKWIEPKICREDLTDAIRLPPSGEKKDCPPCNPGFYNNGSSSCHPCPPGTFSDGTKECKSCPAGTEPALGFEYKWWNVLPTNMKTSCFNVGNSKCDGMNGWEVAGDHIRSGAGGSDNDYLILNLHIPGFKPPTSMTGATGSELGRITFVFETLCSADCVLYFMVDINRKSTNVVESWGGTKEKQAYTHVIFKNATFTFTWAFQRTNQGQDNRRLINDVVKIYSISATNAVDGVAASCRACALGSEQSGSSCVPCPPGHYIEKETNQCKECPADTYLSIHQVYGKEACIPCGPGSKSTQDHSLCYSDCFFYHEKENQSLHYDFRNLSSVGSLMNGPSFTSKGTKYFHFFNISLCGHEGRKMALCTNNISDFTVKEMVTGSDD-LNLVGAFVCQSTIIPSESKGFRAALSSQSIILADTFLGVTVEASLQNVNIKEDMFPVSPSQVPDVHFFYKSSTATTSCINGRSTAVKMRCNPMRPGAGVISVPSKCPAGTCDGCTFYFLWESAEACPLCTEHDFHEIEGACKRGLQEILYVWNEPKWCIKGIALPEKKLSTCETVDFWLKVGAGVGAFTAVLLVALTCYFWKKNQKLEYKYSKLVMTTNSKECELPAADSCAIMEGE--DNEEDVVYSNKQSLLGKLKSLATKEKD----DHFESVQLKSSRCPNI---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UZV7-1", "uniprot_id": "ELAP2_MOUSE", "id": "Q3UZV7-1", "name": "Endosome/lysosome-associated apoptosis and autophagy regulator family member 2", "aln": "MLLLTLRRAKGRDRGRPAGGPRRALSLPWSPAWICCWALAGCQAVWAGDS-SSSGRPLPACQEKDYHFEYTECDSTGSRWRVAIPNSAVDCSGLPDPVKGKECTFSCASGEYLEMKNQVCSKCVEGTYSLGSGIKFDEWDELPAGFSNVATFMDTVVGPSDSRPDGCNNSSWLPRGNYIESNRDDCTVSLIYAVHLKKSGYVFFEYQYVDNNIFFEFFIQNDQCQEMDAT-TDKWVKLTDNGEWGSHSVMLKSGTNILYWRTTGILMGSKAVKPVLVKNITIEGVAYTSECFPCKPGTFSNKPGSFNCQMCPRNTYSEKGAKECIRCKEDSQFSEEGASECVDRPPCTTKDYFQIHTPCDEEGKTQIMYKWIEPKICREDLTDAIRLPPSGEKKDCPPCNPGFYNNGSSSCHPCPPGTFSDGTKECKSCPAGTEPALGFEYKWWNVLPANMKTSCFNVGNSKCDGMNGWEVAGDHIRSGAGGSDNDYLILNLHIPGFKPPTSMTGATGSELGRITFVFETLCSADCVLYFMVDINRKSTNVVESWGGTKEKQAYTHVIFKNATFTFTWAFQRTNQGQDNRRFINDVVKIYSITATNAVDGVAASCRACALGSEQSASSCVPCPPGHYIEKETNQCKECPADTYLSIHQVYGKEACIPCGPGSKSTQDHSLCYSDCFFYHEKENQTLHYDFRNLSSVGSLMNGPSFTSKGTKYFHFFNISLCGHEGRKMALCTNNISDFTVKEMVTGSDDYTNLVGAFVCQSTIIPSESKGFRAALSSQSIILADMFLGVTVDTALQNVNIKEDMFPVSPSQVPDVHFFYKSSTATTSCINGRSTAVKMRCNPMRPGAGVISVPSKCPAGTCDGCTFYFLWESAEACPLCTEHDFHEIEGACKRGLQEILYVWNEPKWCIKGISLPEKKLSTCETVDFWLKVGAGVGAFTAVLLVALTCYFWKKNQKLEYKYSKLVMTTNSKECELPAADSCAIMEGE--DNEEDVVYSNKQSLLGKLKSLATKEKD----DHFESVQLKSSRCPNI---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MWY0-1", "uniprot_id": "ELAP2_HUMAN", "id": "A8MWY0-1", "name": "Endosome/lysosome-associated apoptosis and autophagy regulator family member 2", "aln": "MLFRARGPVRGRGWGRPAEAPRRGRSPPWSPAWICCWALAGCQAAWAGDLPSSSSRPLPPCQEKDYHFEYTECDSSGSRWRVAIPNSAVDCSGLPDPVRGKECTFSCASGEYLEMKNQVCSKCGEGTYSLGSGIKFDEWDELPAGFSNIATFMDTVVGPSDSRPDGCNNSSWIPRGNYIESNRDDCTVSLIYAVHLKKSGYVFFEYQYVDNNIFFEFFIQNDQCQEMDTT-TDKWVKLTDNGEWGSHSVMLKSGTNILYWRTTGILMGSKAVKPVLVKNITIEGVAYTSECFPCKPGTFSNKPGSFNCQVCPRNTYSEKGAKECIRCKDDSQFSEEGSSECTERPPCTTKDYFQIHTPCDEEGKTQIMYKWIEPKICREDLTDAIRLPPSGEKKDCPPCNPGFYNNGSSSCHPCPPGTFSDGTKECRPCPAGTEPALGFEYKWWNVLPGNMKTSCFNVGNSKCDGMNGWEVAGDHIQSGAGGSDNDYLILNLHIPGFKPPTSMTGATGSELGRITFVFETLCSADCVLYFMVDINRKSTNVVESWGGTKEKQAYTHIIFKNATFTFTWAFQRTNQGQDNRRFINDMVKIYSITATNAVDGVASSCRACALGSEQSGSSCVPCPPGHYIEKETNQCKECPPDTYLSIHQVYGKEACIPCGPGSKNNQDHSVCYSDCFFYHEKENQSLHYDFSNLSSVGSLMNGPSFTSKGTKYFHFFNISLCGHEGKKMALCTNNITDFTVKEIVAGSDDYTNLVGAFVCQSTIIPSESKGFRAALSSQSIILADTFIGVTVETTLKNINIKEDMFPVPTSQIPDVHFFYKSSTATTSCINGRSTAVKMRCNPTKSGAGVISVPSKCPAGTCDGCTFYFLWESAEACPLCTEHDFHEIEGACKRGFQETLYVWNEPKWCIKGISLPEKKLATCETVDFWLKVGAGVGAFTAVLLVALTCYFWKKNQKLEYKYSKLVMTTNSKECELPAADSCAIMEGE--DNEEEVVYSNKQSLLGKLKSLATKEKE----DHFESVQLKTSRSPNI---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BBU3-1", "uniprot_id": "A0A8M2BBU3_DANRE", "id": "A0A8M2BBU3-1", "name": "", "aln": "----------------------MEKRALWSSCYIVRFVTL-FLCARASGN-------LPQCKETDYYFEYTECDSTGSRWRVAIPHRQESCTGLPEPVRGTDCTFSCEAGEFLEMSSQQCISCAAGSYSLGSGVRFDQWDSIPAGFSSLATYMD--SGGSGDESMTCNNSSWTAQGTHLESNRDDCTVSLVYAVHLMKQGSVSFDYQYVDSNVFFEFFIQNDQCQEMDQQGSEKWIKLTTSGEWGTHTVNLKSGTNILYWRTTGMLLGGKPVKPVLLKNIQIEGVAYTSECFPCRPGTFSKTPGSSSCDLCSRNTYSGKGASSCTHCT-ESQYSQEGWSQCKERPPCSEKDYFQIHTACDSEGKTQILYRWVEPQVCLENVTGAVKLPPSGEKEDCPPCNPGFYMHNSSTCLPCPQGTYSDGTTECQRCPGGTEPSLGYEYKWWNVLPRNMKTSCFNVGNSKCDEMNGWEVAGDHIRSGVGGSDNDYLILNLRVPGFKLPTSVDDASATEFGRITFIFETNCSADCELYFMIDVNRKSTNVVESWVGNIVRRAYTHIMTKNASVSYTWAFQRTNKATDVRQYVNDIAKIYSITVTNAMDGSASGCHACAMMSQQDGSSCVPCPAGHFINKDTNQCQECPPNTFLYGHHIYGHEACQPCGPGSKSNKEHSVCFNDCTFSHMDQNRTLNYDLSALSSVGSIMNGPSFTSKGTKYYHQFNISLCGAEGRKVAVCTDNVTDMSSKDLQNESADLNNFVETFVCQSTIIPADGRGFRSALSSQSISLADTFLGASVESSLDGVTVNSDLFLKSSQKVPDINFFYRSPQPTASCLNGRSTVVTLHCSPEKSARGELTVPIKCPAGTCNGCEFHFLWESSSACPLCTEADYHSIEGACKGGQQDTLYVWNEPKLCTKGVALPNKSSAHCEVVSLWVKAGIGGGAFMAVLLVSLTCYFWKKNKRLEYKYSRLVMSAN-KDCELPAADSCALAEGEGEENEDDVVYSNTPSLLGKLKAIASKVSDLADGDNSESVQLKSSQSERWVWG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **..:* :. .. *.. ** *:*.**:********:*********: .*:***:**:*.:***** :**:***..* * .* *:******::**:**.:*****.:**:** * *.... ****** .:*.::***********:***** *.* * *:*****.*:*************** ::**:*** .****:*:* **************:*:*.*.*****:*** *************:*****:.*** .*::*.***** ***..* :*. :**:*:** *:* :****: ********.**.******:*:*:**::* *::*.*::*******:********** :.**:* *** **:****.**: **.****:**:********* *************** ***********:**.************::**** ***: .*:.:*:*****:*** ***** ****:*:*********** *. ::****:: ***:.::********:. * *: :**:.*****:.***:** *:.*:***: *:*..*******.**:*:*:****:***.:*:* *::**:*** *******..::**:*:.** * * .:*::*:**: ******:*************:* ******* **:*:*:**:*::*:: *:: * * *:* :*********::.:***:******* *** *:*.:*:::*..:.::.*:* ...::**::***:*. .*:**:*****.*.::*.* :.. * ::** *******:** *:*****:.******* *:*.****** * *: ******** * **::**:*. : **.*.:*:*.* * *** *****:*********::******:***::* *:**********: *** :**::*****. *******::*:* .: *: ******:*:. . ", "identical_positions": 634, "similar_positions": 254, "identity": "61.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3902", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64LC9-1", "uniprot_id": "RBM4B_RAT", "id": "Q64LC9-1", "name": "RNA-binding protein 4B", "aln": "-----MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKLHGVNINVEASKNK---SKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECP--VDRTG--RVADFTEQYN-----------------------------EQYGAVR-----TP---------YTMGYGESMYY--------------NDAYG--------ALD-YYKRYR-VRSYEAVAAAAAASAYNYAEQTMSHLPQVQSSAVPSHLNSTSVDPYDRHLLQNSGSAATSAAMAAAAS--SSYYGRDRSPLRRNAAVLPTVGEGYGYGPESEMSQASAATRNSLYDMARYEREQYVDRARYSAF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VE92-1", "uniprot_id": "RBM4B_MOUSE", "id": "Q8VE92-1", "name": "RNA-binding protein 4B", "aln": "-----MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKLHGVNINVEASKNK---SKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECP--VDRTG--RVADFTEQYN-----------------------------EQYGAVR-----TP---------YTMGYGESMYY--------------NDAYG--------ALD-YYKRYR-VRSYEAVAAAAAASAYNYAEQTMSHLPQVQSSAVPSHLNSTSVDPYDRHLLQNSGSAATSAAMAAAAS--SSYYGRDRSPLRRNAAVLPAVGEGYGYGPESEMSQASAATRNSLYDMARYEREQYVDRTRYSAF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQ04-1", "uniprot_id": "RBM4B_HUMAN", "id": "Q9BQ04-1", "name": "RNA-binding protein 4B", "aln": "-----MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKLHGVNINVEASKNK---SKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECP--VDRTG--RVADFTEQYN-----------------------------EQYGAVR-----TP---------YTMGYGESMYY--------------NDAYG--------ALD-YYKRYR-VRSYEAVAAAAAASAYNYAEQTMSHLPQVQSTTVTSHLNSTSVDPYDRHLLPNSGAAATSAAMAAAAATTSSYYGRDRSPLRRAAAMLPTVGEGYGYGPESELSQASAATRNSLYDMARYEREQYVDRARYSAF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C7Q4-1", "uniprot_id": "RBM4_MOUSE", "id": "Q8C7Q4-1", "name": "RNA-binding protein 4", "aln": "-----MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKLHGVNINVEASKNK---SKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECP--IDRSG--RVADLTEQYN-----------------------------EQYGAVR-----TP---------YTMSYGDSLYY--------------NNTYG--------ALDAYYKRCRAARSYEAVAAAAASAYSNYAEQTLSQLPQVQNTAMASHLTSTSLDPYNRHLLPPSGAAAAAAAAAACTAASTSYYGRDRSPLRRATGPVLTVGEGYGYGHDSELSQASAAARNSLYDMARYEREQYADRARYSAF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IQ97-1", "uniprot_id": "RBM41_DANRE", "id": "Q6IQ97-1", "name": "RNA-binding protein 4.1", "aln": "-----MVKIFVGNLSPNTTAEEIRSLFSQYGKISECDIVKNFGFVHMDSKSEADEAIQNLHHYMLNGMAMNVEMSKGK---PKTSTKLHVGNISSSCTNQELRAKFEEYGPVVECDIVKDYAFVHMERVEDAMEAISGLDNTAFQGKLMSVKLSTSRLRTAPGMGERTGCYRCGQEGHWSKECP--LDQNGSYREGPSSEGFGPVRFDSGGDRGRGFHRGFSGEPAYAGSFAPSHGFTRGAGYAVPGYGRGAGFESAMGYGMPAGYGVGADNSMAPVYGSEAAYGTSGMAYPGALPAYPIRRPPYEERDPYGVVDFYEKYRARPYGGSYFEDRRAVQPPVPPPPTSTPVVRERLPSNLVDPYERHPLPPPPAPTSSYYVRERSPVRR----APHEAEGYAYE-RSRLSPISVLPRTAAYDVP---RDPYAERARYAY-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94901-1", "uniprot_id": "LARK_DROME", "id": "Q94901-1", "name": "RNA-binding protein lark", "aln": "MPGAGTFKLFIGNLDEKTQATELRALFEKYGTVVECDVVKNYGFVHMETEQQGRDAIQNLNGYTLNEFAIKVEAAKSRRAPNTPTTKIFVGNLTDKTRAPEVRELFQKYGTVVECDIVRNYGFVHLDCVGDVQDAIKELNGRVVDGQPLKVQVSTSRVRPKPGMGDPEQCYRCGRSGHWSKECPRLYGSAGGGREPPSPLSAG-------------------------------------------------------GYRDRMYG--------------RDPYP------PPPPPPPFLRDRIMDGFRDYDYYDRRFEDSRDLYERRYQTSRMRDFPPPPISRREPMPLPPTLSGSLRSCSVSRGYDTMFSRRSPPPPRSSNGMSRYGSPTPHGYEDFSRDAFDERMISSRGMR-----------GPSPPGRRYAPY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*:*:*** :: *:*:**.:**.: ***::**:****:: : . :**:**: * *: . ::** :*.: ..:**:.***:: . *:* *::**.*:*****::*.***:: . *. :** *:. .:*: : *::****:*. ****: *****:.******** . * * . . .* . .* . * . . . * . : :. *. . : * *.:. .. * * **: ", "identical_positions": 90, "similar_positions": 85, "identity": "20.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3904", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVR3-1", "uniprot_id": "SHIP2_RAT", "id": "Q9WVR3-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2", "aln": "MASVCGAPSPGGALGSQAPAWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCVLYQKHVHTYRILPDGEDFLAVQTSQGVPVRRFQTLGELIGLYAQPNQGLVCALLLPVEGEREPDPPDDRDASDVEDEKPPLPPRSGSTSISVPAGPSSPLPAPETPTTPAAESTPNGLSTVSHEYLKGSYGLDLEAVRGGASNLPHLTRTLVTSCRRLHSEVDKVLSGLEILSKVFDQQSSPMVTRLLQQQSLPQTGEQELESLVLKLSVLKDFLSGIQKKALKALQDMSSTAPPAPLQPSIRKAKTIPVQAFEVKLDVTLGDLTKIGKSQKFTLSVDVEGGRLVLLRRQRDSQEDWTTFTHDRIRQLIKSQRVQNKLGVVFEKEKDRTQRKDFIFVSARKREAFCQLLQLMKNKHSKQDEPDMISVFIGTWNMGSVPPPKNVTSWFTSKGLGKALDEVTVTIPHDIYVFGTQENSVGDREWLDLLRGGLKELTDLDYRPIAMQSLWNIKVAVLVKPEHENRISHVSTSSVKTGIANTLGNKGAVGVSFMFNGTSFGFVNCHLTSGNEKTTRRNQNYLDILRLLSLGDRQLSAFDISLRFTHLFWFGDLNYRLDMDIQEILNYISRREFEPLLRVDQLNLEREKHKVFLRFSEEEISFPPTYRYERGSRDTYAWHKQKPTGVRTNVPSWCDRILWKSYPETHIICNSYGCTDDIVTSDHSPVFGTFEVGVTSQFISKKGLSKTSDQAYIEFESIEAIVKTASRTKFFIEFYSTCLEEYKKSFENDAQSSDNINFLKVQWSSRQLPTLKPILADIEYLQDQHLLLTVKSMDGYESYGECVVALKSMIGSTAQQFLTFLSHRGEETGNIRGSMKVRVPTERLGTRERLYEWISIDKDDTG-AKSKAPSVLRGSQEHRSGSRKPTSTEASCPLSKLFEEPEKPPPTGRPPAPPRAVPREESLNPRLKSEGTPEQEGVAAPPPKNSFNNPAYYVLEGVPHQLLPLEPTSFARAPIPPTTKNKVAITVPAP----------------QLGRHRTPRVGEGSSSDEDSGG------TLPPPDFPPPPLPDSAIFLPPN---------------LDPLSMPVVRGRSVGEARGPPPPKAHPRPPLPPGTSPASTFL---EEVASADDRSCSVLQMAKTLSEVDYSP-GPGRSALLPNPLELQLPRG-PSDYGRPLSFPPPRIR-ESIQEDLAEEAPCP--QGGRASGLGEAGMGAWLRAIGLERYEEGLVHNGWDDLEFLSDITEEDLEEAGVQDPAHKRLLLDTLQLSK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P549-1", "uniprot_id": "SHIP2_MOUSE", "id": "Q6P549-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2", "aln": "MASVCGTPSPGGALGSPAPAWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCVLYQKHVHTYRILPDGEDFLAVQTSQGVPVRRFQTLGELIGLYAQPNQGLVCALLLPVEGEREPDPPDDRDASDVEDEKPPLPPRSGSTSISAPVGPSSPLPTPETPTTPAAESTPNGLSTVSHEYLKGSYGLDLEAVRGGASNLPHLTRTLVTSCRRLHSEVDKVLSGLEILSKVFDQQSSPMVTRLLQQQSLPQTGEQELESLVLKLSVLKDFLSGIQKKALKALQDMSSTAPPAPLQPSIRKAKTIPVQAFEVKLDVTLGDLTKIGKSQKFTLSVDVEGGRLVLLRRQRDSQEDWTTFTHDRIRQLIKSQRVQNKLGVVFEKEKDRTQRKDFIFVSARKREAFCQLLQLMKNRHSKQDEPDMISVFIGTWNMGSVPPPKNVTSWFTSKGLGKALDEVTVTIPHDIYVFGTQENSVGDREWLDLLRGGLKELTDLDYRPIAMQSLWNIKVAVLVKPEHENRISHVSTSSVKTGIANTLGNKGAVGVSFMFNGTSFGFVNCHLTSGNEKTTRRNQNYLDILRLLSLGDRQLSAFDISLRFTHLFWFGDLNYRLDMDIQEILNYISRREFEPLLRVDQLNLEREKHKVFLRFSEEEISFPPTYRYERGSRDTYAWHKQKPTGVRTNVPSWCDRILWKSYPETHIICNSYGCTDDIVTSDHSPVFGTFEVGVTSQFISKKGLSKTSDQAYIEFESIEAIVKTASRTKFFIEFYSTCLEEYKKSFENDAQSSDNINFLKVQWSSRQLPTLKPILADIEYLQDQHLLLTVKSMDGYESYGECVVALKSMIGSTAQQFLTFLSHRGEETGNIRGSMKVRVPTERLGTRERLYEWISIDKDDTG-AKSKVPSVSRGSQEHRSGSRKPASTETSCPLSKLFEEPEKPPPTGRPPAPPRAVPREEPLNPRLKSEGTSEQEGVAAPPPKNSFNNPAYYVLEGVPHQLLPLEPPSLARAPLPPATKNKVAITVPAP----------------QLGRHRTPRVGEGSSSDEDSGG------TLPPPDFPPPPLPDSAIFLPPN---------------LDPLSMPVVRGRSGGEARGPPPPKAHPRPPLPPGTSPASTFL---GEVASGDDRSCSVLQMAKTLSEVDYAP-GPGRSALLPNPLELQPPRG-PSDYGRPLSFPPPRIR-ESIQEDLAEEAPCP--QGGRASGLGEAGMGAWLRAIGLERYEEGLVHNGWDDLEFLSDITEEDLEEAGVQDPAHKRLLLDTLQLSK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15357-1", "uniprot_id": "SHIP2_HUMAN", "id": "O15357-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2", "aln": "MASACGAPGPGGALGSQAPSWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCVLYQKHVHTYRILPDGEDFLAVQTSQGVPVRRFQTLGELIGLYAQPNQGLVCALLLPVEGEREPDPPDDRDASDGEDEKPPLPPRSGSTSISAPTGPSSPLPAPETPTAPAAESAPNGLSTVSHDYLKGSYGLDLEAVRGGASHLPHLTRTLATSCRRLHSEVDKVLSGLEILSKVFDQQSSPMVTRLLQQQNLPQTGEQELESLVLKLSVLKDFLSGIQKKALKALQDMSSTAPPAP-QPSTRKAKTIPVQAFEVKLDVTLGDLTKIGKSQKFTLSVDVEGGRLVLLRRQRDSQEDWTTFTHDRIRQLIKSQRVQNKLGVVFEKEKDRTQRKDFIFVSARKREAFCQLLQLMKNKHSKQDEPDMISVFIGTWNMGSVPPPKNVTSWFTSKGLGKTLDEVTVTIPHDIYVFGTQENSVGDREWLDLLRGGLKELTDLDYRPIAMQSLWNIKVAVLVKPEHENRISHVSTSSVKTGIANTLGNKGAVGVSFMFNGTSFGFVNCHLTSGNEKTARRNQNYLDILRLLSLGDRQLNAFDISLRFTHLFWFGDLNYRLDMDIQEILNYISRKEFEPLLRVDQLNLEREKHKVFLRFSEEEISFPPTYRYERGSRDTYAWHKQKPTGVRTNVPSWCDRILWKSYPETHIICNSYGCTDDIVTSDHSPVFGTFEVGVTSQFISKKGLSKTSDQAYIEFESIEAIVKTASRTKFFIEFYSTCLEEYKKSFENDAQSSDNINFLKVQWSSRQLPTLKPILADIEYLQDQHLLLTVKSMDGYESYGECVVALKSMIGSTAQQFLTFLSHRGEETGNIRGSMKVRVPTERLGTRERLYEWISIDKDEAG-AKSKAPSVSRGSQEPRSGSRKPAFTEASCPLSRLFEEPEKPPPTGRPPAPPRAAPREEPLTPRLKPEGAPEPEGVAAPPPKNSFNNPAYYVLEGVPHQLLPPEPPSPARAPVPSATKNKVAITVPAP----------------QLGHHRHPRVGEGSSSDEESGG------TLPPPDFPPPPLPDSAIFLPPS---------------LDPLPGPVVRGRGGAEARGPPPPKAHPRPPLPPGPSPASTFL---GEVASGDDRSCSVLQMAKTLSEVDYAPAGPARSALLPGPLELQPPRGLPSDYGRPLSFPPPRIR-ESIQEDLAEEAPCL--QGGRASGLGEAGMSAWLRAIGLERYEEGLVHNGWDDLEFLSDITEEDLEEAGVQDPAHKRLLLDTLQLSK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2I6J1-1", "uniprot_id": "SHP2A_DANRE", "id": "Q2I6J1-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A", "aln": "MAAVGPASPP------PPPLWMHRDLSRAAAEELLARAGRDGSFLVRDSESVSGAYALCVLFQKHVHTYRILPDEENFLAVQTSQGVQPKRFKTLPELIQLYLQPSQGLVTTLLYPVERE---ETTEDRDYSDGEDEKPPLPPRTASTSSMT----GSALVSTDTP--PENVTAANGLSTISHEYLKGNYALDLEAVKQGANSLPHLNKTLLSSCKRLHGEVDKVLCGLEILSKVFDQQSASMVSRMIQQ-SMSQGGDQELEHLVTKLAILKDLLSSIEKKALKALQDMSSSTPAISPLLSIRN-KVIPVQTFEVKLDVYLADLTKIGKSQKYSLSVDVEGGKLVVMKKMKDAQEDWNTFTHDKIRQLIKSQRVQNKLGIVFEKEKDKSQRKDFIFASAKKREAFCQLLQLMKNKHSNQDEPDMISIFIGTWNMGSVPAPKPLGSWILSRGLGKTLDEMAVTIPHDIYVFGTQENSVCDKEWVETLRCSLKEYTDMEYKPIAVQTLWNIKIVVLVKAEHENRISHVGMSSVKTGIANTLGNKGAVGVSFMFNGTSFGFVNCHLTSGNEKIHRRNQNYLDILRQLSLGDKQLNSFDISLRFTHLFWFGDLNYRLDMDIQEILNYINRKEFDPLLKVDQLNLEREKNKIFLRFAEEEISYPPTYRYERGSRDTYVWQKQKATGMRTNVPSWCDRILWKSYPETHIVCNSYGCTDDIVTSDHSPVFGTFEVGVTSQFVSKKGLPKSSEQAYIEFENIEAIVKTASRTKFFIEFYSTCLEEFKKSYENDTQSSDNVNFLRVGWSSKQLTTLKPILSDIEYLQDQHLLLTVKSLDGYESYGECVLALKSMIGSTAQQFHTYLSHRGEETGNIRGSMRVRVPSERMGTRERLYEWISVDKDDMGGPKGRTLPPRTSHDYVKPTSSSSSRKHGSAELSRVSEEGEKSS-TSR-----HTHTKEE----NTHNRGKQDPFESDATTCKNSFNNPAYYILEGVPNQSAALASDILPGSALPPLANKTTAPPAGSVGKSKPPSGSSAQGRWQTSGRSVRPISEEGSSEDDGNIGPHTGSLNRPPPDFPPPPLPKAALEMSENSFGKPRVFSDLADGKIPPPSKPLVSPGLTPPPGGAPGGGVAFCIESPPVLSPNSAPFRRGGGASALDDQSCSVLQMAKTLSEVEYPS-GRERGAS-------QGPTG-PQLRG--LSFPSHPIQEESIAEDLPEEGGLWGAESSSSSLSVDCSVGEWLQKLGLQHYEEGLLHNGWDDLEFLSDITEEDLEEAGVRDPAHKKILLASLKQQQK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:. :. * .* * ******************************:**:*****:************ *:********** :**:** *** ** **.**** :** *** * :..:*** ** **********:.*** . .*.* :.:** * ::.*****:**:****.*.******: **. ****.:** :**:***.******.*************:.**:*::** .:.* *:**** ** **::***:**.*:************::*. . * *: *.****:******* *.**********::********:**:::: :*:****.*****:***************:*******::*******.**:**************:**:********:***********.** : **: *:****:***::***************** *:**:: ** .*** **::*:***:*:*****:.****.*********. ***************************************** *********** *****:**.:*******************************.*:**:***:**********:*:****:*****:**************.*:***.**:*********************:******************************:*****.*:*:*******.************************:***:***:*****:***:* ***:**.******:****************:**********:************* *:***************:****:**:***********:***: * .*.:. . . : :. * ..: .. *. **:: ** **.. *.* :: .:** . : .* : *.. **********:*****:* . . . :.:*. :::..* .. : *: * ****.*: . * . ***********.:*: :. . : * . *:* . *.* . ** ** *: : .:: **:**************:*.. * *.* * * * *. * ****. *: *** ***.**. :.. :* :..:. **: :**::*****:***********************:*****::** :*: .: ", "identical_positions": 835, "similar_positions": 238, "identity": "64.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3920", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R7T9-1", "uniprot_id": "TBC12_RAT", "id": "M0R7T9-1", "name": "TBC1 domain family member 12", "aln": "MMGPEDAG--------------------ACS-----GRNAELLPVPG--PMGQDGKTVP---------ATGGFSGGAVAAEPPGEAGEEEAP------------PPRQLLQRYLAAAAGPLQPGLGG---VEAEAAAVP---------------------------AARGSGMTNGDSGFLLLQDRRGPEEAR-----------RRRTCGRPCLAEPADEGVDGAGGLDDWAAPLEDP------------LRSCCLAAGDTDDPD---------------------------------PTATTSAGRDVGSAESSLGLPDARFGSRNTFEVSRRQSAGDLLPSAGQSAPLPAAEQGPGGTTVRARRSGGFADFFARNLFPKRTKELKSVV-HSAPGWKLFGKVPPRENLQKTSKIIQQEYEARTGRTCKVP--PQSSRRKNFEFEPLSTTALILEDRPSNLPAKSVEEALRHRQEYDEMVAEAKKREIKEAHKRKRIMKERFKQEESIASAMVIWINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRAKERWKSFSESSSDSDME--GLSVADREASLELIKLDISRTFPSLYIFQKGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNRPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSYNLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILLQMDFIHIAQFLTKLPEDITSEKLFSCIAAIQMQNSTKKWTQVFASVTKD-IKEGDKNN-------SPALKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6A039-1", "uniprot_id": "TBC12_MOUSE", "id": "Q6A039-1", "name": "TBC1 domain family member 12", "aln": "MMGPEDAG--------------------ACS-----GRNAELLPVPG--PMGQDGKTVP---------ATSGFSGGAVAAEPPEEAGEEEAP------------PPRQLLQRYLAAAAGPLKPGLGGAEAEEAAAAAVP---------------------------AARGSGMTNGDSGFLLRQDRRGPEEAR-----------RRRTCGRPCLLEPADEGVDGAGGLDDWAAPLEDP------------LRSCCLAAGDTDDPD---------------------------------PAAATPAGRAVESAEPSLGLPDARFGSRNTFEVSRRQSAGDLLPSAGPSAPLPAAEQGPGGTTARARRSGGFADFFARNLFPKRTKELKSVV-HSAPGWKLFGKVPPRENLQKTSKIIQQEYEARTGRTCKAA--PQSSRRKSFALEPLSTTALILEDRPPNLPAKSVEEALRHRQEYDEMVAEAKKREIKEAHKRKRIMKERFKQEESIASAMVIWINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRAKERWKSFSESSSENDTE--GLSVADREASLELIKLDISRTFPSLYIFQKGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSYNLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILLQMDFIHIAQFLTKLPEDITSEKLFSCIAAIQMQNSTKKWTQVFASVAKD-IKEGDKNT-------SPALKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60347-1", "uniprot_id": "TBC12_HUMAN", "id": "O60347-1", "name": "TBC1 domain family member 12", "aln": "MVGPEDAG--------------------ACS-----GRNPKLLPVPAPDPVGQDRKVIR---------ATGGFGGGVGAVEPPEEADEEEEAD------EEEETPPRQLLQRYLAAAGEQLEPGLCYCPLPAGQAGAPPPSAAPRSDACLLGSGSKHRGAEVADGRAPRHEGMTNGDSGFLPGRDCRDLEEARGLARAGGRESRRRRPYGRLRLEGPGDEDADGAGSPSDWASPLEDP------------LRSCCLVAADAQEPEGAGSDSGDSPASSCSSSEDSEQRGVGAGGPEEGAPPATSAERTNGGAEPRLGFSDIHFNSRNTFQVSRGQSARDHLPPAGPPVPLPAAEQGPAGASARARRSGGFADFFTRNLFPKRTKELKSVV-HSAPGWKLFGKVPPRENLQKTSKIIQQEYEARTGRTCKPP--PQSSRRKNFEFEPLSTTALILEDRPSNLPAKSVEEALRHRQEYDEMVAEAKKREIKEAHKRKRIMKERFKQEENIASAMVIWINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRAKERWKSFSETSSENDTE--GVSVADREASLELIKLDISRTFPSLYIFQKGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILLQMDFIHIAQFLTKLPEDITSEKLFSCIAAIQMQNSTKKWTQVFASVMKD-IKEGDKNS-------SPALKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PFQ4-1", "uniprot_id": "A0A8M9PFQ4_DANRE", "id": "A0A8M9PFQ4-1", "name": "", "aln": "MERVEDAGEPKLAPFIDVNDNREEHKARVCGSDTDGAREGSVYISPYADPGGAGQQTLSSVLTGCKAGVLNGFPEQLDMVCPDGEEETQSDTGRVSGTFETEDKPDKAYLNSQMRSAVSFMGKTSPDMKIPNGDVTHEHMDHDQTQLRCLNYTEGFNRKAS-----AALDRGVKVGNGGLLIVNSYDTLSQVPFGALGGLPAPERPVFVHQSDGVLSSGRSCERVSHPSADEAHLCDPDPVYTLTDLSTKLSLSPLAENTSDYTETDPSPEEDFSDTG--PPVRPQNLRTNPGHPISLSCDATPLSPEDDGYFGAEGCVDECLSSGNTFEGVRRQSAPDRVDVD----PNASSDQ-----TLGTKRHG-IADFLTRSLFSWKPKESRAVASHSAPGWKLFGKIQLRDNPLKDSRTIQQEYEFRAGPATGPPLHPPPTRRKNLEFEPLSTTALILEDRPANLPAKSEEESQRHRQEYSEMVAGAKRREMKEAQKKKRQMKERYRQEENIASAMVIWNSEVLPNWESMRNTRRVRDLWWQGVPPSVRGKVWCLAIGNELNITPELYEIFLSRAKEKWRSFSETSSVNENEDCGVSLADRESSLDLIKLDISRTFPSLYIFQKGGPYHDILHSVLGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQMAFFRVDHDLMLKYFAAFEVFFEENLPRLFQHFQNNSLTPDFYLIDWIFTLYSKSLPLDVACRVWDVFCRDGEEALFRTGLGILRLYQDVLLQMDFIHSAQFLSRLPENTPAHTLFSCIANTQMISNNRRWNQVFSTLIKDRLKETDKISNSSSNSNSPALRS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **** .*. .*: .: * * * . :.: . .** . * * :. . * : *: : :* : . . *. *:. *:.*:* .. .:. * : ..... : .. . : * ** * . *. :: .: . :*. . * * :.* ***: * *** * : * .:::* : ::* * :***::*.**. :.** ::*. ***********: *:* * *: ****** *:* : . * .:***.: :**************.****** **: ******.**** **:**:***:*:** ****::***.******** .*:***** **.*****:*****:*********.**:********************:*:****:** .: * *:*:****:**:************************:***:******************************************:***:*******.:******:*********.:** **:. .****:*****************:************** ************:*:******** ****::***: .:..****** ** ...::*.***::: ** :** ** . ****:*", "identical_positions": 386, "similar_positions": 148, "identity": "45.95%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3922", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AB59-1", "uniprot_id": "RHG27_MOUSE", "id": "A2AB59-1", "name": "Rho GTPase-activating protein 27", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAADVEGDVYVLVEHPFEYTGKDGRRIAIQPNERYRLLRRSTEHWWHVRREPGGRPFYLPAQYVRELPALGDPAPAPQPS---------VPQQRPAVPEPLAYDYRFVSTP---VGADGSSA----------EPRGRASSLCGPARQR---TGGQRNSLAPGGPACLYVRPAAPVRPAQSLDDLARGGTAPPAGLLGSAGHFKASS-------------------VAGSWVCPRP-----LAPSDSE-NVYEAIPDLRCP---------------------------PRAESPKQVDDPPEP-----------VYANVERQPRATSPRSAAAPPRL-------------SPVWETHTDTGTGRPYYYNPDTGVTTWESPFETP--------EGTTSPATSRAS------VGSGESLETEWGQYWDEESRRVFFYNPLTGETAWEDETEELEEDHQEQLEMQPSLSPRSP--------------------------GQQRPPTPETDYPELLASYPEEDYSPVGSFSDPGPASPLVAPPGWSCQITPDKQMLYTNQFT-----------------------------QEQWVRLEDQHGKPYFYNPEDSSVQWELPQVP-------------IPAPRSVRKSSQ----------------------DSDTP------AQASPPEE----------------------KIKTLDKAGVLHRTKT----------------------------------------------------------VDKGKRLRKKHWSTSWTVLEGGVLTFFKDSKTSAAGGLRQPSKLSTPEYTVELKGASLSWAPKDK-----------------------------------SSKKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAEGISELSADLLQGEEGEP--SSADFGSSERLGSWRE--EDVRQNAASPSLSPGGL----------------------------------------------------------------------------------------------ESDLSRVRHKLRKFLQRRPTLQSLRDKGYIKD--QVFGCALAQLCERERSPVPRFVQQCIRTVEA--RGLDIDGLYRISGN-LATIQKLRYKVDHDERLDLDDG------RWEDVHVITGALKLFFRELPEPLFPFSHFHQFIAAIKLQDPAQ---------------------RSRCVRDLVRTLPAPNQDTLRLLIQHLCRVIEHGEQNRMTVQNVAIVFGPTLLRPEMEEASMPMTMVFQNQVVELILHQCADIFPPH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6TLK4-1", "uniprot_id": "RHG27_RAT", "id": "Q6TLK4-1", "name": "Rho GTPase-activating protein 27", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAADVEGDVYVLVEHPFEYTGKDGRLIAIQPNERCRLLRRSTEHWWHVRREPGGRPFYLPAQYVRELPALGDPVPAPQPS---------VLQQRPTVPEPLAYDYRFVSTP---VGADGSSA----------EPRGRASSLCGPARQR---TSGQRNSLAPGGPACLYLRPAAPVRPAQSLDDLARGGTAPPAGLLGSAGHFKASS-------------------VAGSWVCPRP-----LARSDSE-NVYEAIPDLRCP---------------------------PRAKSPKQVDEPPEP-----------VYANVERQPQVTSPRSAAAPPRL-------------SPVWETHTDAGTGRPYYYNPDTGVTTWESPFEAP--------EGATSPTTSRAS------VGSGESLETEWGQYWDEESGRVFFYNPLTGETVWEDETEELEDDPEEQLEMQPSLSPRSP--------------------------GQQRPPTPETDYPELLTSYPEEDYSPVGSFSDLGPTSPLVAPPGWSCQITPEKQMLYTNQFT-----------------------------QEQWVRLEDQEGKPYFYNPEDSSVQWELPQVP-------------VPAPRSGRKSSQ----------------------DSDTP------AQASPPEE----------------------KIKTLDKAGVLHRTKT----------------------------------------------------------VDKGKRLRKKHWNASWTVLEGGVLTFFKDSKTSAASGLRQPSKLSTPEYTVELRGASLSWAPKDK-----------------------------------SSKKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAEGIEELSADLPQREEGEP--SSADFGSSERLGSWKE--EDVRPNAASPSLNPGSQ----------------------------------------------------------------------------------------------ESDLSRVRHKLRKFLQRRPTLQSLREKGYIKD--QVFGCALAQLCERERSPVPRFVQQCIRTVEA--RGLDIDGLYRISGN-LATIQKLRYKVDHDERLDLDDG------RWEDVHVITGALKLFFRELPEPLFPFSHFHQFIAAIKLQDPAQ---------------------RSRCVRDLVRTLPAPNHDTLRLLIQHLCRVIEHGEQNRMSVQNVAIVFGPTLLRPEMEEASMPMTMVFQNQVVELILHQCADIFPPH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZUM4-1", "uniprot_id": "RHG27_HUMAN", "id": "Q6ZUM4-1", "name": "Rho GTPase-activating protein 27", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAADVVGDVYVLVEHPFEYTGKDGRRVAIRPNERYRLLRRSTEHWWHVRREPGGRPFYLPAQYVRELPALGNPAAAAPP----------GPHPSPAAPEPLAYDYRFVSAAA-TAGPDGAPE----------ESGGRASSLCGPAQRG---AATQRSSLAPGLPACLYLRPAAPVRPAQSLNDLACAAVSPPAGLLGSSGSFKACS-------------------VAGSWVCPRP-----LARSDSE-NVYEVIQDLHVP---------------------------PPEESAEQVDDPPEP-----------VYANIERQPRATSP-GAAAAPLP-------------SPVWETHTDAGTGRPYYYNPDTGVTTWESPFEAA--------EGAASPATSPAS------VDSHVSLETEWGQYWDEESRRVFFYNPLTGETAWEDEAEN---EPEEELEMQPGLSPGSP--------------------------GDPRPPTPETDYPESLTSYPEEDYSPVGSFGEPGPTSPLTTPPGWSCHVSQDKQMLYTNHFT-----------------------------QEQWVRLEDPHGKPYFYNPEDSSVRWELPQVP-------------VPAPRSIHKSSQ----------------------DGDTP------AQASPPEEKVPAELDEVGSWEEVSPATAAVRTKTLDKAGVLHRTKT----------------------------------------------------------ADKGKRLRKKHWSASWTVLEGGVLTFFKDSKTSAAGGLRQPSKFSTPEYTVELRGATLSWAPKDK-----------------------------------SSRKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAQGIQELSAELPP-EESES--SRVDFGSSERLGSWQEKEEDARPNAAAPALGPVGL----------------------------------------------------------------------------------------------ESDLSKVRHKLRKFLQRRPTLQSLREKGYIKD--QVFGCALAALCERERSRVPRFVQQCIRAVEA--RGLDIDGLYRISGN-LATIQKLRYKVDHDERLDLDDG------RWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQAR---------------------RSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEETSMPMTMVFQNQVVELILQQCADIFPPH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B2D3-1", "uniprot_id": "A0A8M2B2D3_DANRE", "id": "A0A8M2B2D3-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNPDPLFAPQHVWATMSLSQQVLVNYEYTYTARDGRNVSIKPNEHYILVNKTNEEWWHVQKDAADKPFYIPAKYVTELPPETSQTPLDPPEEFSG---YESLQFGSQTADPAEVTLRVPDSIKRDTEKDGHRISTFIIPKEFFELKGLDPDPIKTEAEAGPPVSSNTSSPTNGETAFIILPPPVYTVNTTQSTETDTRSVDDPKDSVGRPRVDSSTI-------------------DEDIQMLNRAGWSEVLDVMGKEKNVYESLDTVREPE-------------------------SPKDEADMTVNTTPVTPDAPMVEDDTAVYVNIPRKRQTTINNSSPIASLLQDFPEPPENFLLDSAGWQVHTDDQSGQEFYYQPSTGRSTWENPLSSRSMESPVGTEGGRSPPSFPQSPACSPVAPAPRRWSSDWEKVLDESTGRHYFFNTVSGQSSWDPPEDV---DSPGRLMFLDDCPPPLP--------------------------EEDYPASPELEEASPVSIPAEYSLIHVKKVSIPRVSLDRSSPAGWSLDIDSEGTWTFTSEYT-----------------------------QEQWIKSLDDQGRTYYYLRDGSKSQWNLPEINPGQGGVAAQWLALLPYSKNVAGSSPGWYSAS----PGQYGVGNGASGEQDTVGSNWRHSAGYPDDKNHSSYIQNTSDSEASSSPDTPHNVSNLEKAGILNKTKV----------------------------------------------------------SENGKKVR-KNWGHSWTVLHGGKLTFHKDPKSTPAG-ASSKTNQILPEFTVDLKGATINRAPKDK-----------------------------------SSKKNVLELKTRTGAEYLIQYDTDSIIQDWHKVILDTIHQLNGDQHHSEEEDE--VIDKSPTLDREERPFE--KRTMSTATRQPSTSSTS----------------------------------------------------------------------------------------------EAEQKKVRTKLKKFLLKRPTLQSVKDKGYIRE--NVFGCHLHNLCSQEKTRVPSFVEKCIRAVEK--RGLEIDGLYRVSGN-LAVIQKLRFKADHED-LDLEEG------NWD-IHVITGALKLFFRELQEPLFPYNLFNEFICAIKTPDYYS---------------------KISHMRNLVRSLPPPNHDTMEALFSHLRRVIQHGNENRMTVQNVAIVFGPTLLKPEEETASIATYMVFQNQIVEFLLSEFESIFHM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JCF3-1", "uniprot_id": "X2JCF3_DROME", "id": "X2JCF3-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQTTTSQRPVTPGTPDSAHIVIGAAGFVAHERRQPGK----TLMNCFRDRSTTSSSS--------------------SQAQHAYVRGHSVTSSTLFRLEGSGGSN----------------------------CTLDKAGKQDTGRPEAVVLLRELKTRPNK-LALLKSSSSKDLTRLFLDDSTNTAVL-------------------VSN---------------------------------------------------------------------------------------TSIDVCSSNSSSGGSPAVGRS-----------------KSGRDRRNGLECCSSCSK--------------------------------------------------RWHDLKQRMHTLEQDLLVQTTYS-----------------QELEQKVG--------------------------EMSRQLTELLQERDRERDKDKARFAAAGGVAAPGKRTAHGSPN--------VRPSRLVAWMN-----------------------------LSNWFKSRPS---------------------------------------------------------------------------------------------------------------VETLREQRIFFDEPC----------------------------------------------------------FDT-----------------ELEMVLKHDQHRTVPRIVVDCCDLIEQKYRRSTQPIEGIYRQCGD-----------------------------------YNKIQTLRFS-IDANDYDSLRQPDVDIHTLTGVLKLFLREIKSPLVRVNEAKT--FIGQ--------------------------PNQWL----------------------------------------------------------------------------------------------LTDLSAKLDSLKRLIRSLPESN-RDTMDYIFG--HFNRITKVPLQQISAETLSISVTPSIFHTVP--QGVHMQDIQQLLREGETLADCVKLMIEYQGRIFDRLR------LIQTAHLLCRCVERFANHSKSEILNPKPNTPLYLPHLYTHSRF---------------------APESVSNPDHIVYRCTADRRRLSMRNLKKTLSQPD------------------------------LLFHNLF---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39083-1", "uniprot_id": "RGA1_YEAST", "id": "P39083-1", "name": "Rho-type GTPase-activating protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASTAPNEQFPSCVRCKEFITTGHAYELGCDRWHTHCFACYKCEKPLSCESDFLVLGTGALICFDCSDSCKNCGKKIDDLAIILSSSNEAYCSDCFKCCKCGENIADLRYAKTKRGLFCLSCHEKLLAKRKYYEEKKRR-------LKKNLPSLPTPVIDNGHTDEVSASAVLPEKTFSRPASLVNEIPSGSEPSKDIETNSSDIVPHFITGYNDSDDNSGSS-------------------KFGSNVSIDVIGPEENSTEHVNDDVKEEAEAPSANM-------------------------SLNVATDPTLSCKEPP---------SHSRNLLNKTPLRNSSGQYLAKSPSS---------YRQGIIVNDSLEESDQIDPPNNSSRNASELLTSVLHSPVSVNMKNPKGSNTDIFNTG------EISQMDPSLSRKVLNNIVEETNALQRPVVEVVKEDRSVPDLAGVQQEQAEKYSYSNNSGK--------------------------GRKISRSLSRRSKDLMINLKSRATGKQDSNVKLSPASKVTSRRSQDLMRDNDSHTGLDTPNS-----------------------------NSTSLDILVNNQKSLNYKRFTDNGTLRVTSGKETALEEQKNHSFKSPSPIDHLLQSPATPSN---------VSMYRTPPLDSSLTFDRRNGSSYSNQNYSIPSWQKTPKTQLENSDNFEEQKETLYENSESRNDPS----------------------------------------------------------LDK--EIVTAEHYLKQLKINLKELESQREELMKEITEMKSMKEALRRHIESYNSEKNKLYLDSNE-----------------------------------LSNNPPMINEISLGESPPVKHVATASSVARSSVKPKFWKFFSSAKPQTEQSIQGVSTNNTNSIVKSAPVLLSAPSSGSNSGRLEISPPVL----------------------------------------------------------------------------------------------QNPNEFSDVRLVPIENDANMGQSKDGEEYLDGS-NLYGSSLVARCNYENNEIPMILSVCIDFIESDEENMRSEGIYRKSGSQLVIEEIEKQFSAWKVQQNTETPNIL---TEQDLNVVTGVLKRYLRKLPNPIFTFQIYEPLMRLVKSKKMMENLPFVGGKLSLEAKNSDTYMSSKSALKNILEDLPREHYRVLRVLSEHIEKVTRYSHWNRMTLYNLALVFAPGLIR-DFSGEKDIIDMKERNYIVAFIFGNYKDILT--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q06407-1", "uniprot_id": "RGA2_YEAST", "id": "Q06407-1", "name": "Rho-type GTPase-activating protein 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSADPINDQSSLCVRCNKSIASSQVYELESKKWHDQCFTCYKCDKKLNADSDFLVLDIGTLICYDCSDKCTNCGDKIDDTAIILPSSNEAYCSNCFRCCRCSNRIKNLKYAKTKRGLCCMDCHEKLLRKKQLLLENQTK--------NSSKEDFPIKLPERSVKRPLSPTRINGKSDVSTNNTAISKNLVSSNEDQQLTPQVLVSQERDESSLNDNNDNDNSKD---------------REETSSHARTVSIDDILNSTLEHDSNSIEEQSLVDNEDY-------------------------INKMGEDVTYRLLKPQ--------RANRDSIVVKDPRIPNSNSNANRFFSIYDK------EETDKDDTDNKENEIIVNTPRNSTDKITSPLNSPMAVQMNEEVEPPHGLALTLSEAT------KENNKSSQGIQTSTSKSMNHVSPITRTDTVEMKTSTSSSTLRLSDNGSFSRPQTADNLLP--------------------------HKKVAPSPNKKLSRSFSLKSKNFVHNLKSKTSEMLDPKHPHHSTSIQESDTHSGWGVSSTHTNIRKS------------------------KAKKNPVSRGQSDSTIYNTLPQHGNFTVPEFN-------HKKAQSSLGSISKKQNSNDTATN-----------------RRINGSFTSSSSGHHIAMFRTPPLESGPLFKRPSLSSESAHHRSSSLQTSRSTNALL----------------------------------------------------------EDDSTKVDATDESATSLEKDFYFTELTLRKLKLDVRELEGTKKKLLQDVENLRLAKERLLNDVDN-----------------------------------LTREKDKQSASSRESLEQKENIATSITVKSPSSNSDRKGSISNASPKPRFWKIFSSAKDHQVGDLESQQRS---PNSSSGGTTNIAQKEI----------------------------------------------------------------------------------------------SSPKLIRVHDELPSPGKVPLSPSPKRLDYTPDGSHLYGSSLQARCAYEKSTVPIIIRCCIDRIEKDDIGLNMEGLYRKSGSQTLVEEIENEFAQNNSLHSDTLSPKLNALLNQDIHAVASVLKRYLRKLPDPVLSFSIYDALIDLVRNNQLIERLPLNNDKFLDSPQKVTIYEMVLKSLLEIFKILPVEHQEVLKVLAAHIGKVRRCSERNLMNLHNLSLVFAPSLIH-DFDGEKDIVDMKERNYIVEFILGNYRDIFKQA", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39960-1", "uniprot_id": "BEM2_YEAST", "id": "P39960-1", "name": "GTPase-activating protein BEM2/IPL2", "aln": "MKGLLWSKNRKSSTASASSSSTSTSHKTTTASTASSSSPSSSSQTIRNSTSGASPYMHSHHHHGQGHSHHRGEDNNRDKRKSSVFPPSKQYTSTSSSQVNLGMYHSDTNTRSSRSIASTLKDDSPSVCSEDEISNSSSQKSNAQDETPIAYKKSAHSKDSLLPSRSSSLSPPQSRCSTGTTLEKSLNTSGISNSSGTNNNNSNNNNDNEQKQRNVIHLNSENYDTTVFKTGWVNKSHGQTVATNYNSSMTAPSSSSSSSSQNLRNDAYSRNRESRFYGNDGSSLKNDDSSSTTATNSGNDVASARSSMAIDPQMLVPDYRLYRAQLKGCVLNLYKSGLNSNIKFFDPTLPASNSSIANENHQQKKQQTNNQAQAEALHQKQSFGQMGEPITLDLKYLSEVYPHPDLRQDSDGKIISGTIESLCHTVLFYPGPKQSDVPNEKSLSKTHRAVINLLLMFPLLDHFIKFLKVFNQFGLSFTKNKSRLTNNSTQFYNISPAVDDSMTQRLALTAKTILDVFPGFLLDEPMLKTIISLLDTISLHNDEISNNLKIKIANKHNELMKLTAFTRSLPMATSSTHELEIILDPSHFLSLDITTLADEVHHINLKFDKVWAPKFDYSLLYDSKFINRRIVSLNPLVFNNDQNIHFLGRLLISHLFPTNPEFSKKVTPKVRAELLDKWVQIGCRFEHLGDMVSWLAVATIICSIPVLRSSSWKYVPDQSLKTIFKDWVPTIIQLERRQRTSKSTSSVFILAPPNLDDDFTRANVISYFGDLLIHADDLPSDTKFKYLEKKINRTKNAFHKWQQRLQAIDSTRHKTNSTENVRDNDSPNNVVYQLWKFHLSQPPLNIEGIMKLSVQHEPPIIDQKAYSTIGSQRSALVTGSYLPILFNELFPNYSLFPKNTLVGAASDAKLPPPRSSARLSKSLSISEPIPIASNSHTMGSLTDDAMSSKNDNNKVTGVGKIDGPVIKEMSSKQSNKQRLLKSVRDVFNIDMDVFHISDELVFKSVYDNDGKSRPASMVIETPKRFSQHSSMLINNPATPNQKMRDSLDTTGRLSKTLENMDFFNNIGQVSDSLKESIIRVVLKSSSLEKIFDLLVLTSNIFSKLVDTKDLENYYYHQRQRGHSTRGLSDDNIGLLDYAFVKLTMDNDIFTETFFNTYKSFTTTTTVLENMAKRYVGAKSCSVSISKILDRSDDSKMKINEDTNLVSSSLYDQNFPVWDMKVTDDENINLIYMAKIQIGAAEAILHLVKNHYSDFTDDLCNNSTLLDIIKIMEQEVSTEWPTRIANSKLQKSLPENFVIETENLLTTLTDLFHGIKSAYQKQLYRPIGVNRTQKRITDILNSFNTFSFTDLNNIIDDPSFSDDMIRSFQKLHSTNYEDILEWIYQLDNFISKKFNLVSKKDWIVLFQELELLSKESLVSFFNYPLHFKSSKLINPGYLQLHEFEISNLFTWISTLILKDDNGTESLFFEKLPQSIKLLIKLHTSLTTFFVMEISNVNKSSSERLTTCKVILQILNYIRWKNGSLDLFDSEEDESPHAICPHIPAFIETAIAHAIISPESRNYELSWIKASEKLSDPTKGTQNLRSISNVLEKIDDIHIKRFIEIDDVFSKNCKNLCPCPGWFISRLLEISQFVPNMSITNSKLINFDKRRFVNNIISNVLDLIPNEREFPLDIEMSDENPSKRTTFGRILFNNFEDVNKVYRKKTKKVSESEAISERFQEQGVFNEILVNEIEKIKREARKLEVLLDQEKILKNSAALHQAVPKKNRKSVIISGTHSDNDHSYNINKNTGQTPSLGSVMESNNSARNRRDSRASFSTNRSSVVSNSSHNGVSKKIGGFFRRPFSIGGFNTSSSNYSLNSILSQEVSSNKSILPSILPEVDSMQLHDLKPSYSLKTFEIKSIMEIINHRNIPAYYYAFKIVMQNGHEYLIQTASSSDLTEWIKMIKASKRFSFHSKKYKGKTHNKIFGVPLEDVCERENTLIPTIVVKLLEEIEL--RGLDEVGLYRIPGSIGSINALKNAFDEEGATDNSFTLEDD---RWFEVNAIAGCFKMYLRELPDSLFSHAMVNDFTDLAIKYKAHAMVN----------------EEYKRMMNELLQKLPTCYYQTLKRIVFHLNKVHQHVVNNKMDASNLAIVFSMSFINQEDLANSMGSRLGAVQTILQDFIKNPNDYFKQ-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . . .. . . . : . . . : . . . : : . .. . . . :. . :. : : .: .: : . . : : .: : .. . :: : . : : . : . :: :. : : . ", "identical_positions": 0, "similar_positions": 63, "identity": "0.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3932", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AA00-1", "uniprot_id": "A0A8I6AA00_RAT", "id": "A0A8I6AA00-1", "name": "Ankyrin repeat domain-containing protein 11", "aln": "MPKGGCSKTPQQEDCSLSNDMVEKQTGKKDKDKVSLTKTPKLDRTDGGKEVRERVTKRKLPFTVGANGEQKDSDTEKQGPERKRIKKEPVP-RKSGLLFGMGLSGIRAGYPLSERQQVALLMQMTAEESANSPVDTTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSPTMVNLLLGKGTYTSSEESS-TESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKLKAKNPEPQK-TVTPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRRE--AKSNSFISIPKMEVRSYSKNNTLAPKKAAHRILSDT--SDEEDVSASIGAGEKLRLSAHTMLPSSKARESSSSRQQKEKNKLKKKRKKETKG---KEVRFGKRSDKFCSSGSESESSESEEDDGDSVGSSGCLK-GSPLVLKDPSLFSSLSASSTSSHGSAVAQKHSSGHTDQHTKHWRTDNWKAISSPAWSEVSSLSDSSRTGLTSESDCSSEGSSVESLKPTRRK-QEHRKRGSLQSMP-ERRGT---FHPCADGAVPKLDKEGKVVKKHKTKHKHKHKEKGPCS---VSQEL---KLKSFTYEYEDSKQKPDKAILLENDVSTENKLKVLKHD------RDKLSKTKSEDKEWLFKD----EKALKRMKDVSKDTSRAFREERDRPSKTERERSTKEKSPKEEKLRLYKEERKKKSKDRPFKLEKKNDMKE--VSKEKEKAFREDKEKLKKEKLCRDDAAFDDYCNKSQFLDHEDTKFSLSDDQQERWFSDLSDSSFDFKGEDSWDS-VTDYRDIKSDSVAKLILETVKEDSKEKKRDNKTREK-------RDFRDSFFRKRDRDCVDRNSEKRRDHTEKQRSFPSYLSEKDKKRRESAE------------GGRDRRDTLEGSRERRDGRIRSEEVHREDLKECGCDSTFKDKSDCDFTKTLEPWERPHAAREKEKKDALEKDRKEKGRAEKYKDKSGER------ERNEKSILEKCQKDKEFEKCFKEKKD-GKEKHKDTHSKD--RKTPFDQLREKKEKAFSSLIS---EDFSERKDDRKG---KEKSWY-IADIFTDESEDEKEECVASSFKTGETG---DSQRAESLQEKEDGRE-HPSDRHRKASSDRQH-TEKPRDKEPKEKRKDRGAAEGGKDKKE---KIFEKHKEKKDKECAE-KYKERKDRASVDSAPEKKNKQKLPEKVEKKHFVEDKAKSKHKEKPEKDHSRE--RKSSRGPDVEKSLLEKLEEEALHDYREDSNDKISEVSSDSFADHGQEPSLSTLLEVS-FSEPPAEDKARESTCLS---EKLKERERERHRHSSSSS-KKSHERER--AKKEKADKKEKGEDYKD-GGGGRKDASQYEKDFADAEAFGGSYTTKADTEEDLDKAIELFSSE-KKDRNDSEREPAKKLEKELKPYGSSTISILKEKKKREKHREKWREEKEKHRDKHIDGFLRHHK--------DEPKPAAKDKDNPPNCFKEKSREESLKLSEAKLKEKFKENAEREKGDS-VKMSNGNDKPLPSRDANKKDSRPREKLLGDGDLMMTSFERMLSQKDLEIEERHKRHKERMKQMEKMRHRSGDPKLKEK-KPTDDGRKKSLDFPSKKALGLD-----KKVKEP--APVLPTGEGKPHSGPGTESKDWLAGQPLKEVLPASPRTEQGRPTGVPTPTSVVSCPSYEEVMHTPRTPSCSADDYPDLVFDCTDSQHSMPVSTTSTSACSPPFFDRFSVASSVVAENAG-QTPTRPISTNLYRSISVDIRRTPEEEFSVGDKLFRQQSVPAASSFDSPVQHLLEEKAPLPPVPAEKFACLSPEYYSPDYGIPSP---KVDTLHCPPTAVVSATPPPDS---VFSNLPPKSS-PSPRGELLTPAIEGALPPDLG-------LPLDATEDQQATAAILPPEPS----YLEPLDE--------------GPFNTVITEEPVEWTHSAAEQSLP----------------SSLIASASETPVSWPVG--------------------SELMLKSPQR-FAESPKHFCPGEPLHSTTPGPFSAAEPTYPVSPGS-------YPLPAPEPALEEVKDGGTGAIPVAIAAAEGAAPYTAPTRLESFFSNCKPHPDAPLDTAPEPASVTTVAQVEALGPLESSFLDSSHSISALSQVEPVSWHEAFTSPEDDLD-LGPFSLPELPLQAKDASDVEAETAEASPAPPVESPPGPTGVLSGGDVPASTTEE---------PPAPPPQEASPQLSTE-------PEPSEETKLDVVLEAAAETEVLADDS-APEASISNLVPAPSPPEQQRPAGGGDEETEAEDPSAAPCCAPDGPTTDGLAQAPNS---------AEAACVVAAVEGPPGNIQPEATDPEPKPTSEAPK---APKVEEVPQRMTRNRAQMLASQSKQ------------------------------------GIPATEK--DSMPAPASRAKGRAPEEEDAQAQHPRKRRFQRSGQQ--LQQQLNTSTQQTREVIQQTLAAIVDAIKLDAIEPYHSDRSNPYFEYLQIRKKIEEKRKILCCITPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFKQQEAVRGKLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQGDENKSVRDRFNARQFISWLQDVDDKYDRMKTCLLMRQQHEAAALNAVQRMEWQLKAQELDPAGHKSLCVNEVPSFYVPMVDVNDDFVLLPA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q4F7-1", "uniprot_id": "ANR11_MOUSE", "id": "E9Q4F7-1", "name": "Ankyrin repeat domain-containing protein 11", "aln": "MPKGGCSKTPQQEDFALSNDMVEKQTGKKDKDKVSLTKTPKLDRSDGGKEVRERATKRKLPFTVGANGEQKDSDTEKQGPERKRIKKEPVA-RKSGLLFGMGLSGIRAGYPLSERQQVALLMQMTAEESANSPVDTTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSPTMVNLLLGKGTYTSSEESS-TESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKLKAKNPEPQK-TVTPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKE--AKANSFISIPKMEVKSYSKNNTLAPKKAAHRILSDT--SDEEDVSVSIGAGEKLRLSAHTMLPGSKARESSSSRQQKEKNKLKKKRKKETKG---KEVRFGKRSDKFCSSGSESESSESEEDDGDSVGSSGCLK-GSPLVLKDPSLFSSLSASSTSSHGSAVAQKHGSGHTDQHTKHWRTDNWKAISSPAWSEVSSLSDSSRTGLTSESDCSSEGSSVESLKPTRRK-QEHRKRGVLQSAPSEKRSS---FHPCTDGAVPKLDKEGKVVKKHKTKHKHKHKEKGQCS---VSQEL---KLKSFTYEYEDSKQKSDKAILLESDLSTENKLKVLKHDREHLKKEDKLGRMKPEDKDWLFKD----EKVLKRIKDANKDMSRAFREDKDRASKAERERATKDKSPKEEKLRLYKEERKKKSKDRASRLERKNDMKEDKLSKEKEKAFKEDKEKLKKEKLYREDAAFDDYCNKSQFLDHEDTKFSLSDDQQERWFSDLSDSSFDFKGEDSWDS-VTDYRDIKNDSVAKLILETVKEDSKEKKRDNKIREK-------RDFKDSFFRKRDRDCLDKNSEKRRDQTEKHKSIPSYLSEKDKKRRESAE------------GGRDRR----------DGRIRSEEVHREDLKECGFESSFKDKSDCDFPKNLEPWERPHAAREKEKKDALEKERKEKGRADKYKEKSSER------ERSDKSTLDKCQKDKEFEKCFKEKKD-GKEKHKDIHSKD--RKASFDQLREKKEKVFSSIIS---EDFSERKDDRKG---KEKSWY-IADIFTDESEDEKDDCVAGSFKATEAS---DTQRVDGLPEKEEGRE-HPSDRHRKSSSDRQH-TEKPRDKEPKEKKKDRGASEGGKDKKEKMEKIFEKHKEKKDKECAE-RYKDRKERASADSAPEKKNKQKLPEKVEKKHFAEDKVKSKHKEKPEKEHSRERERKPSRGPDVEKSLLEKLEEEALHDYREDSNDKISEVSSDSFADHGQEPSLSTLLEVS-FSEPPAEDKARDSACLS---EKLREKER--HRHSSSSS-KKSHERER--AKKEKAEKKEKSEDYKDSISSVRKDASQFEKDFLDAETYGVSYPTKADVEEELDKAIELFSSE-KKDRSDPEREPAKRIEKELKPYGSSAISILKEKKKREKHRERWREEKERHRDKHVDGFLRHHK--------DEPKPAAKDKDNPPNSFKEKSREESLKLSETKLKEKFKENTEREKGDS-IKMSNGNDKLVPSRDSGKKDSRPREKLLGDGDLMMTSFERMLSQKDLEIEERHKRHKERMKQMEKMRHRSGDPKLKEK-KPTEDGRKKSLDFPSKKALGLD-----KKVKEP--APTLTTGESKPHSGPGTESKDWLSGQPLKEVLPASPRTEQSRPTGVPTPTSVVSCPSYEEVMHTPRTPSCSADDYPDLVFDCTDSQHSMPVSTASTSACSPPFFDRFSVASSVVSENAAGQTPTRPISTNLYRSISVDIRRTPEEEFSAGDKLFRQQSVPAPSSFDSPVQHLLEEKAPLPPVPAEKFACLSPGYYSPDYGIPSP---KVDTLHCPPTAVVSATPPPDS---VFSNLPPKSS-PSPRGELLSPAIEGTLPPDLG-------LPLDATEDQQATAAILPQEPS----YLEPLDE--------------GPFTTVITEEPVEWTHTAAEQGLSS---------------SSLIASASENPVSWPVG--------------------SELMLKSPQR-FAESPKHFCPGESLHSTTPGPYSAAEPTYPVSPGS-------YPLPAPEPALEEVKDGGTGAIPVAISAAEGAAPYAAPARLESFFSNCKSHPDAPLDTAPEPTGVTAVAQVEALGPLESSFLDSNPSISTLSQVEPVSWHEAFTSPEDDLD-LGPFSLPELPLQAKDASDVEAEAAKASPVPPAESPPGPTGVLGGGDVPAPAAEE---------PPAPPPQEASPQLSTE-------PEPSEEPKLDVVLEATVETEVLADDS-APEASISNSVPAPSPPQQQ-PPGGGDEEAETEDPSATPCCAPDGPTTDGLAQAHNS---------AEASCVVAAAEGPPGNVQAEATDPEPKPTSEVPK---APKVEEVPQRMTRNRAQMLASQSKQ------------------------------------GIPAAEK--DPMPTPASRAKGRASEEEDAQAQHPRKRRFQRSSQQ--LQQQLNTSTQQTREVIQQTLAAIVDAIKLDAIEPYHSDRSNPYFEYLQIRKKIEEKRKILCCITPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFKQQEAVRGKLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQGDENKSVRDRFNARQFISWLQDVDDKYDRMKTCLLMRQQHEAAALNAVQRMEWQLKAQELDPAGHKSLCVNEVPSFYVPMVDVNDDFVLLPA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UB99-1", "uniprot_id": "ANR11_HUMAN", "id": "Q6UB99-1", "name": "Ankyrin repeat domain-containing protein 11", "aln": "MPKGGCPKAPQQEELPLSSDMVEKQTGKKDKDKVSLTKTPKLERGDGGKEVRERASKRKLPFTAGANGEQKDSDTEKQGPERKRIKKEPVT-RKAGLLFGMGLSGIRAGYPLSERQQVALLMQMTAEESANSPVDTTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSPTMVNLLLGKGTYTSSEESS-TESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKHKAKNPEPQK-ATAPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKE--TKSNSFISIPKMEVKSYTKNNTIAPKKASHRILSDT--SDEEDASVTVGTGEKLRLSAHTILPGSKTREPSNAKQQKEKNKVKKKRKKETKG---REVRFGKRSDKFCSSESESESSESGEDDRDSLGSSGCLK-GSPLVLKDPSLFSSLSASSTSSHGSSAAQKQNPSHTDQHTKHWRTDNWKTISSPAWSEVSSLSDSTRTRLTSESDYSSEGSSVESLKPVRKR-QEHRKRASLS----EKKSP---FLSSAEGAVPKLDKEGKVVKKHKTKHKHKNKEKGQCS---ISQEL---KLKSFTYEYEDSKQKSDKAILLENDLSTENKLKVLKHDRDHFKKEEKLSKMKLEEKEWLFKD----EKSLKRIKDTNKDISRSFREEKDRSNKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLKEDKISKEKEKIFKEDKEKLKKEKVYREDSAFDEYCNKNQFLENEDTKFSLSDDQRDRWFSDLSDSSFDFKGEDSWDSPVTDYRDMKSDSVAKLILETVKEDSKERRRDSRAREK-------RDYREPFFRKKDRDYLDKNSEKRKEQTEKHKSVPGYLSEKDKKRRESAE------------AGRDRKDALESCKERRDGRAKPEEAHREELKECGCESGFKDKSDGDFGKGLEPWERHHPAREKEKKDGPDKERKEKTKPERYKEKSSDK------DKSEKSILEKCQKDKEFDKCFKEKKD-TKEKHKDTHGKDKERKASLDQGKEKKEKAFPGIIS---EDFSEKKDDKKG---KEKSWY-IADIFTDESEDDRDSCMGSGFKMGEAS---DLPRTDGLQEKEEGREAYASDRHRK-SSDKQH-PERQKDKEPRDRRKDRGAADAGRDKKE---KVFEKHKEKKDKESTE-KYKDRKDRASVDSTQDKKNKQKLPEKAEKKHAAEDKAKSKHKEKSDKEHSKE--RKSSRSADAEKSLLEKLEEEALHEYREDSNDKISEVSSDSFTDRGQEPGLTAFLEVS-FTEPPGDDKPRESACLP---EKLKEKER--HRHSSSSS-KKSHDRER--AKKEKAEKKEKGEDYKE--GGSRKDSGQYEKDFLEADAYGVSYNMKADIEDELDKTIELFSTE-KKDKNDSEREPSKKIEKELKPYGSSAINILKEKKKREKHREKWRDEKERHRDRHADGLLRHHRDELLRHHRDEQKPATRDKDSPPRVLKDKSRDEGPRLGDAKLKEKFKDGAEKEKGDP-VKMSNGNDKVAPSKDPGKKDARPREKLLGDGDLMMTSFERMLSQKDLEIEERHKRHKERMKQMEKLRHRSGDPKLKEKAKPADDGRKKGLDIPAKKPPGLDPPFKDKKLKES--TPIPPAAENKLHPASGADSKDWLAGPHMKEVLPASPRPDQSRPTGVPTPTSVLSCPSYEEVMHTPRTPSCSADDYADLVFDCADSQHSTPVPTAPTSACSPSFFDRFSVASSGLSENAS-QAPARPLSTNLYRSVSVDIRRTPEEEFSVGDKLFRQQSVPAASSYDSPMPPSMEDRAPLPPVPAEKFACLSPGYYSPDYGLPSP---KVDALHCPPAAVVTVTPSPEG---VFSSLQAKPS-PSPRAELLVPSLEGALPPDL-----------DTSEDQQATAAIIPPEPS----YLEPLDE--------------GPFSAVITEEPVEWAH-PSEQALA----------------SSLIGGTSENPVSWPVG--------------------SDLLLKSPQR-FPESPKRFCPADPLHSAAPGPFSASEAPYPAPPASPAP----YALPVAEPGLEDVKDG-VDAVPAAISTSE-AAPYAPPSGLESFFSNCKSLPEAPLDVAPEPACVAAVAQVEALGPLENSFLDGSRGLSHLGQVEPVPWADAFAGPEDDLD-LGPFSLPELPLQTKDAADGEAEPVEESLAPPEEMPPGAPGVINGGDVSTVVAEE---------PPALPPDQASTRLPAELE-----PEPSGEPKLDVALEAAVEAETVPEER-ARGDPDSSVEPAPVPPEQR-PLGSGDQGAEAEGPPAASLCAPDGPAPNTVAQAQAADGAG-PEDDTEASRAAAPAEGPPGGIQPEAAEP--KPTAEAPK---APRVEEIPQRMTRNRAQMLANQSKQ------------------------------------GPPPSEKECAPTPAPVTRAKARGSEDDDAQAQHPRKRRFQRSTQQ--LQQQLNTSTQQTREVIQQTLAAIVDAIKLDAIEPYHSDRANPYFEYLQIRKKIEEKRKILCCITPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFRQQEAVRGKLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQGDENKSVRDRFNARQFISWLQDVDDKYDRMKTCLLMRQQHEAAALNAVQRMEWQLKVQELDPAGHKSLCVNEVPSFYVPMVDVNDDFVLLPA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AUK7-1", "uniprot_id": "A0A8M3AUK7_DANRE", "id": "A0A8M3AUK7-1", "name": "Ankyrin repeat domain-containing protein 11", "aln": "MPKGGGSKTPQLEDFPLSTDMVEKQGGKKDKDKGSSNKTPKLDRSDGVKEMKEKAPKRKLPFTVGANGDQKDSDSEKQGPERKRIKKEPTNTRKSGLPFGMGMPGIRAGYPLSERQQVALLMQMTAEESVNSP-DTTPKHQSQSSLGQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGEARRIKELINEGADVNVKDFAGWTALHEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDASNNGHLKVVKLLLRYGGDPCQSNRRGETPLKVANSQTMLNLLLGKITYSSSEESSSADSSEEEDSPSFAPSSSVDGNNTDSEFEKGLKLKGKGMDPPKSTTTPVKDEYEFDEDDEEERVPPVDDKHLLKKEFRKEPVSKTNNLISIPKMEVKTYSKSNSLTPKKAVRRILSDSNSSDEDDRTLCFTPTTTPRQPAPQTNIKSRDSTSLNSKQQKEKSKVKKKRKKETKNNVNKEVRFNKVN-KFCTSDSEIGDLES-EDDKGSIQNTNCVKDSSTLSLKDPSVFTSLSVTSSSSHGSLNSQKHTQSLAEQHPKQWRTDGWKTVSSPTMSDVSSLSDSVRTRLSSESDYSSADSSVESVKQVKKKVQDSRKKNNTHVNAVDKKNSELYKTSNTEGAISKADKDGKVLKKHKVKHKHKSKEKDKAPSVVLSQDMNEKFVKSFSFDFDDTRQKS---LIVETESPSENRVKLSKHEKDHFKKEDRLSKGKSEDKDWPVKETQRVVKEEKSKKTKESNKEKVNKEERDKPLKTEKERSIKDK-AKEEKQKAHKDDKKKKSKDKSLKTDKKNEQKEEKHFKS-EKSVKEEKEKSKRDKSIKEEPDYDDFDLKNHLL--EDTKMSASDDPHDRWQSDMS-SDSSLYGDDSWDTPVKEY---KANNAVKLIVETVKEESRDRRKENKFKDKKTDHADKRPEKETASKKKDKDTSDKKTENKKDWTDKQKFNSGQTMEKEKKRKESAESVKEKKDKDSVDCGRDRKDSYEFTKERKDSKAKQESLR----DDYGSEAFFKDKPESETTCKSDPRERNHSGKEREKK-IDGVEKKDKSKGEKHKDKPKDRNLDQEKEKPEKNAIDRSLKEKDLERASKDKRDGVKEKHKDSHSKDKERKMSSEQSKDKKEKASLDKHADKEKDFLEFKKEERKPEKKEKTWYTIADIFTDESEDEDDNYNGGVAKLSDSLGLSDSHRKDSTPDIDEMDN-FQTDKHKKYSEGKTHSIEKQKDKEHKDKKKEKAAFDAGKERKAS----MEKHKDKKDKDSTETKHKERKDRSSVDSNQEKKSKLKLLD---KRDVSDEKSKNKYKDKTEHLKDRK---LSKGSGENEKSLLEKLEEEAMNDYKDDSNDRNSEISLDSFTDRGHEPVLSNFYDSSNISIPDMSEERRESLSITNPQDRFKEKER--HRHSSSSSSKKSHDKEKEKVKKEKSEKKDKSEEIRESYGRRESLPFDKEPMPLEADPYTFPYGSKVDGEDDLDKTLEFEKEMSKKDKTNSIMNSDK----------------LKDKKKKEKHKEKIKEEKHKYSDG--LGSFRHSK--------EEQKSGLKEN-TQISSIKEKSKEDCSKF-DGKNKDRIKDIVDKDRTDSKSKVKDENDKFSQSKETIRKDNRPREKLLVDGDLRLTSFGKMLSLKDQEIEERHKRHKERMKQMEKLRHRSGDPKLKDKTKSNEE-LKKNRSELSKKTGSVDAALKEKKIKEIGLPTQMMSPDRKPQPIDSQNSKDWLAGHQMKESLPASPRPDQNRPTGVPTPTSVISCPSYEEVMQTPRTPSCSAEDYSDIMFDGLECHNSS-ATTMSMNACSPSFFDRFSNSSNTFQEGTCITPAKNMQLPLVSRSVTSDVRRPLDVEFKAEADKLLRQHVQEGTEFESSASQLSEDK-----MAADRLNCLSSCFSPTADMSPRPDLLQHERLQDEVSAVNSISDGNEYSGCVYNNYLMKPSTPVHRPDPQEPCLDIAAPPTPAPAALPPMDIDDLSEPHQSGPGLMPAHPVSVSDYLPPVVEEQEDEEEEEEEEEDNDDDDDFVEDPTESHHAPEESMQARNNPTYLLGIEESDKKAWLECSDRRDPDVLPITPAHPQDNYMENSCDQSLGWNSEALMKSPHESYREVEAAVSKISSPYSHSDCDLQHIPNVIPVTPPHSTYSRAYCPSQIPDSHYEDPKDTVEDLPSPGRPVAETLESESP--QLENFFTDCKPTPEENQMDLELPCMIKDNRQESPTYPAEISMPVAPP----VSEDPVVSWADPFSGAADEMDDMGPFSIPELPFQEKEMQDPDITAPEIAENKHSPTLTRPPVIETSENVEMINVDLSSLSKAPCSPTVVPHDESSQDLVPPVSKDDYTPQCELEPEPQNIPDVLPIKETISEERGGFEGMDINNDNLLATEEQDHEYRKKEINPDAMMPSVMVQYLELPVTTKPHLLGQNPVVALGPSCSPHLTVHIPAVSMPTSTHVSETLETTAKLSVTIPVSEAPKKIEEIPQRITRKKAQMLANQNKQSATLSSSSITHSVSSSPITTSVTTSCVTVEKEKETISSSNVQTSAPSAPALITKTKGRPIEDDDNQSQHPRKRKFPKSGQQQVQVQLVNTAMKQTREMIQQTLAVIVNAIKLDEIEPYHSDRSNPYFEYLQIRKKIEEKRKILCYITPQAPQCYADYVTYTGSYLLDGKPLSKLHIPVIAPPPSLSEPLKELFRQQEAVRGKLRLQHSIEREKLIVSCEQEVLRVHCRAARTIANQAVPFSACTMLLDSEVYNMPSESQGDENKSVRDRFNARQFISWIQDVDDKYDRMKTCLLMRQQHEAAALNAVQRMEWQLKVQELDPAGHKSLCVNEVPSFYVPMVDVNDDFVLLPA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** .*:** *: .**.****** ******* * .*****:* ** **::*:..*******.****:*****:**************. **:** ****:.*************************.*** ****** ***:: *********************************:********.**************************:*************************:**** ***********:* ****:********** **:****** **:****** ::******:*********************** *.*. :* * :.:*************::*************::*:* :*:*.:********::*:*.*:::**** :*****: ***:* : . . . * .* *: . .::*****.*:*********. :****.* . ***:* ** . ** *** .*: .:.*:* .*.* *****:*:***.:*:***** :**: . ::**.*:****.**::***: *:******* ** *:**** ** .*****:* .::: *: **: :::.. . ::**:.* **:***:****.***** ***. .. :**:: :***:::::*::**. :::*.: .:**::*: **: .::*.: * *:*:* .*: * * * ..: .: :*::*:. *:*:**: *:* .**** : :*:::******:. : ::**: ** *. ** .:*:*** *::* :::. :*:: *.::* ****:* *** ::** **:* *. .: *:****: *.:* * :...***:*****:*::::::.: ::* * ::. :*:*:* *:::*:::: *:*:: .. **:***:**** ****: *.: : *. : .: * :: ****.: : :* ** *..:*:*** ::*:* : :::*:*. :: :: :*. :::. *:*::::. *:*:* ****** *.** ** . :* ::****. . : :** * *.:.: ***:** ***********: :. .. * :: * * :. : :: : . :*:*:* *..: * *: :*** ::::*::.* :.*:::* :****:****:.:* ::*:**:*:*.** :**.* ** : *:. ::* *.*:*:*.:: :.:: .. . : ************:::*::****: **:* ***:*:*:** *: : : * :: * .:: *:* .:. ::::*:** ******** ****::*: .****::**:*.*: :: . .. . : * :*:.: .* *.* *::***::*: . ***:.:. :. * **:***:***:*: ::**.:: * * :** : :* *.. ::: . :*:**::: :: : * *:::*: .:::: *. *:.: *** *::. :** ******* **** :*** :*** ** ******************:**********:* *. :: **. . :**. .:* **:** .. : : * :. . :*****:* :** ******.:*.***********:*********:*********:**.*::** :.::* ..* . .****.****** :*. . *.: .. . . : **:: *:**. : **.. . : :* * :.::*. *:: :.*::: ***. : .. * * : : *: :** : : : *:.. *.* * * : *.:: : ** * :* :*: ..::* .* ** *: * . :.*:*.* * . *. . : * . . * *: *: ::***:. : * .. .. :* : . *..* . .:. *: ** . . . ..:* . :. **.**::**. *: * : * .. * * *: . :.: *.* :.*:.. *::* :****:****:* *: * : . : : . .. : . :* .: *.. * :::* * . *: . *.: : :. *.:.:: . . . :* : .:: *.. :.. . . .. : .... *.. .*: :. * : * . ::**:***:**::*****.*.** . . :. . *: :::*.* *::* *:******:* :* ** * :**: :****:******.**:***** ********:********************* **********:*****************************:*******:***************************:********************************* **********************:************************************.***********************************", "identical_positions": 1266, "similar_positions": 741, "identity": "43.76%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3936", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V656-1", "uniprot_id": "G3V656_RAT", "id": "G3V656-1", "name": "RNA methyltransferase", "aln": "-----------------------MIEMAAEKEPFLVPAPPPPLKDESGGGGGPEVRSHQEAASGELLDGTERGPGPRAHSAG--------------ATASG--------------------GGGPQAQTHGEPHG----RAAAPADVGEERRGGGGTDLGPPAPPRPRNGYQPHRPPVGGGGKRRNSCNVGGGSGGSFKHPAF-KRRRRVNSDCDS-----------------------------------------------------------------------------------------VLPSNFLLGGNIFDPLNLNSLLDEEVSRALNAETPKSSP---LPAKGRDPVEILIPKDITDPLSLNTCTDEAH--VVLASPLK---IGRKRHRHRGPHHQQQQ------------------------------------------ASGGNDS-QAVLPTDPLTPSVHGEGAT--QQHRGQNRDDPQPYELNTAINCRDEVVSPLPSALQGSSGSLSAPPAASVTSAPS-------------------------------------------------------------------------------------------------------------------------------------SSSSRHRKRRRTSSKSEAGARGGSQGSKEK------------------------------------------------------GRGSGGGR--HHHPLP----------ATGFKKQQLKFQYGNYCKYYGYRNP-SCEDMRLRVLK--PEWFQGRDVLDLGCNVGHLTLSIACKWGPARMVGLDIDPRLIHSARQNIRHYLSEELRLQAQTS----EGDPG--------TEGEEGTTTVRKR------------------------------------SCFPASLTASRGPIAAPHLPLDGADTS----VFPNNVVFVTGNYVLDRDELVDAQRPEYDVVLCFSLTKWVHLNWGDEGLKRMFRRIYRHLRPGGILVLEPQPWSSYCRRKSLTETIYKNYFRIQLKPEQFSSYLTSPEASSVRCTCSTRPDLPATEWLSELEVVKRLPLLLLRTWKKRKLSQGLS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K3A9-1", "uniprot_id": "MEPCE_MOUSE", "id": "Q8K3A9-1", "name": "7SK snRNA methylphosphate capping enzyme", "aln": "-----------------------MIEMAAEKEPFLVPAPPPPLKDESGGGGGPEVQSHQEAASGELRDGTEHGPGPRAHSAG--------------AAASG--------------------GGGPQAQAHGEPHG----RAAAPADVGEERRGGGGTDLGPPAPPRPRNGYQPHRPPGGGGGKRRNSCNVGGGSGGSFKHPAF-KRRRRVNSDCDS-----------------------------------------------------------------------------------------VLPSNFLLGGNIFDPLNLNSLLDEEVSRALNAETPKSSP---LPAKGRDPVEILIPKDITDPLSLNTCTDEAH--VVLASPLK---IGRKRHRHRGPHHQQQQQ-----------------------------------------ASGGNDSNAAVLPTDPLTPSLHGEGATQQQQNRGQNRDAPQPYELNTAINCRDEVVSPLPSALQGSSGSLSAPPAASVTSAPST------------------------------------------------------------------------------------------------------------------------------------SSSSRHRKRRRTSSKSEAGARGGSQGSKEK------------------------------------------------------GRGSGGGRH-HHHPLP----------ATGFKKQQLKFQYGNYCKYYGYRNP-SCEDVRLRVLK--PEWFQGRDVLDLGCNVGHLTLSIACKWGPARMVGLDIDPRLIHSARQNIRHYLSEELRLQAQTS----EGDPG--------TEGEEGTITVRKR------------------------------------SCFPASLTASRGPIAAPQVPLDGADTS----VFPNNVVFVTGNYVLDRDELVDAQRPEYDVVLCFSLTKWVHLNWGDEGLKRMFRRIYRHLRPGGILVLEPQPWSSYCKRKSLTETIYKNYFRIQLKPEQFSSYLTSPEVG------FSSYELVATPNNTSRGFQR--PVYLFH--KARSPSH-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L2J0-1", "uniprot_id": "MEPCE_HUMAN", "id": "Q7L2J0-1", "name": "7SK snRNA methylphosphate capping enzyme", "aln": "-----------------------MIEMAAEKEPFLVPAPPPPLKDESGGGGGPTVPPHQEAASGELRGGTERGPGRCAPSAGS------------PAAAVGRESPGAAATSSSGPQAQQHRGGGPQAQSHGEARLSDPPGRAAPPDVGEERRGGGGTELGPPAPPRPRNGYQPHRPPGGGGGKRRNSCNVGGG-GGGFKHPAF-KRRRRVNSDCDS-----------------------------------------------------------------------------------------VLPSNFLLGGNIFDPLNLNSLLDEEVSRTLNAETPKSSP---LPAKGRDPVEILIPKDITDPLSLNTCTDEGH--VVLASPLK---TGRKRHRHRGQHHQQQQ------------------------------------------AAGGSES-HPVPPTAPLTPLLHGEGASQQPRHRGQNRDAPQPYELNTAINCRDEVVSPLPSALQGPSGSLSAPPAASVISAPP-------------------------------------------------------------------------------------------------------------------------------------SSSSRHRKRRRTSSKSEAGARGGGQGSKEK------------------------------------------------------GRGSWGGRHHHHHPLP----------AAGFKKQQRKFQYGNYCKYYGYRNP-SCEDGRLRVLK--PEWFRGRDVLDLGCNVGHLTLSIACKWGPSRMVGLDIDSRLIHSARQNIRHYLSEELRLPPQTL----EGDPG--------AEGEEGTTTVRKR------------------------------------SCFPASLTASRGPIAAPQVPLDGADTS----VFPNNVVFVTGNYVLDRDDLVEAQTPEYDVVLCLSLTKWVHLNWGDEGLKRMFRRIYRHLRPGGILVLEPQPWSSYGKRKTLTETIYKNYYRIQLKPEQFSSYLTSPDVG------FSSYELVATPHNTSKGFQR--PVYLFH--KARSPSH-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KQ55-1", "uniprot_id": "MEPCE_DANRE", "id": "A3KQ55-1", "name": "7SK snRNA methylphosphate capping enzyme", "aln": "-----------------------MIEMSFDKETVLS----------CEGQTDPTSQEFNINDTSALHPPGNTTENNLSKDAG------------------------------------------SEASLEKSATT-------------DNNASSESAVLGAESSKQSHNGTKPQQQKVN---KRRNTMSAG------FKHPGYGKRRRRANSESES-----------------------------------------------------------------------------------------VLPTNFLLGGNIFDPLNLNSLLDEEVNKALNAETPKSSP---LPAKNRDPVEILIPRDITDPLNLN-CLSTGD--SLLVSPLK---SGGGRRRHRNKHHGANT---------------------------------------------GRVSTEGIGLTESNGCAAVKDDGTSLVSMTNVHLESTIADQTLLDSTLESSNKSSLTSNDNEVKEKTVDCSTAHLTANPTN------------------------------------------------------------------------------------------------------------------------------------PPSSRQRKRRRAGSRTENSSSSSEQHNESQ------------------------------------------------------GGNSRSGVSDRQQPYPNQWRPQYSNNNQNPQQPKKKFQYGNYNKYYGYRNPGMSEDPRIRVMN--PDWFRGKDVLDLGCNTGHLTLFIAKNWRPASIVGLDIDGSLIHAARQNIRHYLSEVQVQHSRRSGENTKADRGE-------VSGEEKDKDKTSK------------------------------------HSFPVSLRISRGPIAGPPLPETNTHSLP-PGDFPANVTFIKGNYVLESDVLLQTQREEYDVILCLSVTKWVHLNWGDAGLKRFFHRVYKHLRPGGLFILEPQPWSSYNKRKKLTEAICKNYHSIRLKPDQFSSFLTT-EVG------FSSYELIGTSQNYSKGFQR--PISLYH---KRPSSLK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7K480-1", "uniprot_id": "MEPCE_DROME", "id": "Q7K480-1", "name": "7SK snRNA methylphosphate capping enzyme bin3", "aln": "MEKRLSDSPGDCRVTRSTMTPTLRLDQTSRQEPLPQQPDNGPAAAPGKSKSPTPLPGKSQAAQHHQFRAPQQQQGPKNRNKAWSKRQHKAGGKHNPSACVGASSGQAQSTGSSVIAATLLPTAASAHKADLENIQNIHNKNLTAGGGVNHHGNAGTAHHGGGGGAGAHHAAAGGHHHHHNTRLAQNAAAGGASGGGTIQMHKKMLRGHHHHVLCAGNNANHTCCLVTGCNGSSIGGVGVAGSGGATASAGGGGASCKEAQSCKDTSSLSGNSSIAGSAGAGNAVHYCCGRSKFFLPEKRLRKEVIVPPTKFLLGGNISDPLNLNSLQNENTSNASSTNNTPATTPRQSPITTPPKVEVIIPPNIHDPLHLLDPVDSMEYEKQLTSPMKRAGPGGGMLHHRQHHYRTRKNRKRRRFDSNNTSHAGDEGGVGSELTDEPPLPAATSSLAASPVAAPLNVGGSLLLSESAAPAPGETAEMGQQQEQAHVHSPQSASTTTTAAEMPTPTPTSAAAATATAEHKEQSAPAPTATSSPQRQQQHVAAAAEELPTPETSAAAETPAEEMLLSCSATSASLVASTLAERRASRDLRLDLSSTCYGVGGTGLSFGGSISSSVGSSFGGGGRKRKISESSTSQKSKKFHRHDAMDKIVSPVVPQPGAWKRPPRILQPSGARKPSTRRSTSVSESELLSPVEEQPPKQLPLIGVEIPRDDTPDLPDHGLGSPLSTTSGATSHTAGEQDSLAGVDISMGDTLGSGVVGKAPLTSSLMLEPAKIPPIKMLPKFRADGLKYRYGNFDRYVDFRQMNEFRDVRLQVFQRHVELFENKDILDIGCNVGHMTITVARHLAPKTIVGIDIDRELVARARRNLSIFVRIPKEEKLLEVKAEPTVDAKANIAVKDETSGAAHKKTRRGKRRRKVHQGIHHHHHHHHDLEQLQQQQKLNSLLVKPHEFFPISFPLTYGRIPRILSSSKSPNMLGNKNQFPANVFFRHTNYVLKDESLMASDTQQYDLILCLSVTKWIHLNFGDNGLKMAFKRMFNQLRPGGKLILEAQNWASYKKKKNLTPEIYNNYKQIEFFPNKFHEYLLSSEVG------FSHSYTLGVPRHMNKGFCR--PIQLYAKGDYTPNHVRWSDAYYPQTPYEAYRGIYATLPVHRMGGGGSSAGGSNSGHAQMLHLSSSSRSQNYDTPHYAGSASGSASCRQTPMYQPTYNPLETDSYQPSYDMEYLNHMYVFASPLYQTVWSPPASLRKSSSHTPVFGSVRDAELDGDGSGGGGSGGGSYHRHVYPPNDDTCSPNANACNAFNSIRDADTDDSNQLPGGSRRHVYATNCGESSSSPQVNHHDAVGEFVDGLMDDEQKSSTGGGTGGAAYCDLSDA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : :*.. . . . : . . . . . . . :.. .. : * . .::. : :*: * :: * :: : . . * *::******* ******** :*:...: .::.. ::. * . **::** :* *** * . . *.**:* * :** *: . : : . . . :. .: . . .:. : * ...:*: . **: * :* . : . : * . . : *::***: :* .:*: .* *::*:: : *..:*:**:***.**:*: :* : * :**:*** *: **:*: :: * ..* : ** *: : * *. . ... ** ** * ****. : *: :: :**::**:*:***:***:** *** *:*::.:***** ::**.* *:** ::*.** * :** *.: *::* .:* : :.. : .. . . : *: * ", "identical_positions": 136, "similar_positions": 177, "identity": "9.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-395", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BZZ5-4", "uniprot_id": "API5_HUMAN", "id": "Q9BZZ5-4", "name": "Apoptosis inhibitor 5", "aln": "-MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLGTLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENAGNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQK----VEIGQKRAS-EDTTSGSPPKKSSA-GPKRDARQIYNPPSGKYSSNLGNFNYEQRGAFRGSRGGRGWGTRGNRSRGRLY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35841-1", "uniprot_id": "API5_MOUSE", "id": "O35841-1", "name": "Apoptosis inhibitor 5", "aln": "-MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQAFSPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLSTLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENAGNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQK----VEIGQKRTS-EDTSSGSPPKKSPG-GPKRDARQIYNPPSGKYSSNLSNFNYER--SLQGK------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "R4GDP5-1", "uniprot_id": "R4GDP5_DANRE", "id": "R4GDP5-1", "name": "", "aln": "MAATVEELYRNYGILADAKEDLSTHKDAYQVILDGVKGGAKEKRLAAQFIPKFFSSFPELADAAINAQLDLCEDEDVSIRRQAIKELPRFASGENLPRVADILTQLLQTDDSAEFNQVNTALISIFKIDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTMPEDIMTKEVEDYIFVETKKVLEDVTGEEFVLLMRILSGLKSMQTVSGRQQLVELVVEQAFLEQALNPADTDSVDRLLQCTRQALPLFSKNVHSTRFVTYFCEFVLPNLSQLTSPVAELDIQLEVLKLLAEMSPYCGDMDKLEVNLNMLFEKLLEFMPLPPEE-ENGENAANEEPKLQFSYVECLLFSFHQLGKKLPDFLIDKVSAEKLKDFKIRLQYFARGLQVYIRQLRVALQGKTGDALKTDENKIKVVALKITNNINVLIKDLFHNPPSYKSTVTLSWKPVQKTEAAAAIGQKRRSGEDIGATATTKKHPTNLPRRDARQIYNPPSGKYSASIGNFSYEQRGGFRGGRG-RGFGGRGNRSRGRIY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .***************.*::. ***************:**************. ******:*************************:**:************************ **.**:****:**********************************:*::::*****: *:.*:**************:*:*******:*************.*** ***::.*:*.*.***********:****************** *****. **:** ***************.:****:***.**. **:****:******* ******.***************:******:****** *:.**************************:*******:****:************************ ***************** . ***** * ** : :..** . *:***************:.:.**.**: .::* ", "identical_positions": 414, "similar_positions": 66, "identity": "77.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3951", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7L1Q6-1", "uniprot_id": "5MP2_HUMAN", "id": "Q7L1Q6-1", "name": "eIF5-mimic protein 2", "aln": "MNNQKQQKPTLSGQRFKTRKRDEKERFDPTQFQDCIIQGLTETGTDLEAVAKFLDASGAKLDYRRYAETLFDILVAGGMLAPGGTLADD--MMRTDVCVFAAQEDLETMQAFAQVFNKLIRRYKYLEKGFEDEVKKLLLFLKGFSESERNKLAMLTGVLLANGTLNASILNSLYNENLVKEGVSAAFAVKLFKSWINEKDINAVAASLRKVSMDNRLMELFPANKQSVEHFTKYFTEAGLKELSEYVRNQQTIGARKELQKELQEQMSRGDPFKDIILYVKEEMKKNNIPEPVVIGIVWSSVMSTVEWNKKEELVAEQAIKHLKQYSPLLAAFTTQGQSELTLLLKIQEYCYDNIHFMKAFQKIVVLFYKAEVLSEEPILKWYKDAHVAKGKSVFLEQMKKFVEWLKNAEEESESEAEEGD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CQC6-1", "uniprot_id": "5MP2_MOUSE", "id": "Q9CQC6-1", "name": "eIF5-mimic protein 2", "aln": "MNNQKQQKPTLSGQRFKTRKRDEKERFDPTQFQDCIIQGLTETGTDLEAVAKFLDASGAKLDYRRYAETLFDILVAGGMLAPGGTLADD--MMRTDVCVFAAQEDLETMQAFAQVFNKLIRRYKYLEKGFEDEVKKLLLFLKGFSESERNKLAMLTGVLLANGTLNASILNSLYNENLVKEGVSAAFAVKLFKSWINEKDINAVAASLRKVSMDNRLMELFPANKQSVEHFTKYFTEAGLKELSEYVRNQQTIGARKELQKELQEQMSRGDPFKDIILYVKEEMKKNNIPEPVVIGIVWSSVMSTVEWNKKEELVAEQAIKHLKQYSPLLAAFTTQGQSELTLLLKIQEYCYDNIHFMKAFQKIVVLFYKAEVLSEEPILKWYKDAHVAKGKSVFLEQMKKFVEWLKNAEEESESEAEEGD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P7P5-1", "uniprot_id": "5MP2_RAT", "id": "Q6P7P5-1", "name": "eIF5-mimic protein 2", "aln": "MNNQKQQKPTLSGQRFKTRKRDEKERFDPTQFQDCIIQGLTETGTDLEAVAKFLDASGAKLDYRRYAETLFDILVAGGMLAPGGTLADD--MMRTDVCVFAAQEDLETMQAFAQVFNKLIRRYKYLEKGFEDEVKKLLLFLKGFSESERNKLAMLTGVLLANGTLNASILNSLYNENLVKEGVSAAFAVKLFKSWINEKDINAVAASLRKVSMDNRLMELFPANKQSVEHFTKYFTEAGLKELSEYVRNQQTIGARKELQKELQEQMSRGDPFKDIILYVKEEMKKNNIPEPVVIGIVWSSVMSTVEWNKKEELVAEQAIKHLKQYSPLLAAFTTQGQSELTLLLKIQEYCYDNIHFMKAFQKIVVLFYKAEVLSEEPILKWYKDAHVAKGKSVFLEQMKKFVEWLKNAEEESESEAEEGD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PD83-1", "uniprot_id": "5MP2A_DANRE", "id": "Q6PD83-1", "name": "eIF5-mimic protein 2-A", "aln": "MNNQKQQKPTLTGQRFKTRKRDEKERFDPSQFQESIVQGLNQTGTDLEAVAKFLDASGAKLDYRRYAETLFDILVAGGMLAPGGTLSDD--LTRTEYCLFTASEDLETMQAYAQVFNKLIRRYKYLEKGFEEEIKKLLLFLKGFTESERNKLAMLTGILLANGNISASILNSLFNENLVKEGVSAAFAVKLFKSWINEKDINSVAASLRKVGMDNRLMELFPANKRSCEHFSKYFTDAGLKELSDFARNQQSIGARKELQKELQEQMSRGETLKDIIAYVREEMKKTSISEQTMIGIVWTSVMSSVEWNKKEELVTEQAIKHLKQYSPLLKAFTSQGLSELTLLLKIQEYCYDNIHFMKAFQKIVVLLYKADVLSEEVILKWYTEGHVAKGKSVFLEQMKKFVEWLKNAEEESESEEEEGD--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VNE2-1", "uniprot_id": "PKRA_DROME", "id": "Q9VNE2-1", "name": "Protein krasavietz", "aln": "-MSQKTERPVLSGQRIKTRKRDEREKYDPTGFRDAVIAGLEKTEGDLEQISKYLDSAGNKLDYRRYGEVLFDILIAGGLLVPGGSISQDGEKPRTSYCIFDAPESMESMRNHEQVFVKLIRRYKYLEKMFEEEMGKVLLFVKGFTPSERIKLARMTALWLVNGSVPPNVLLVLNNEHLIKDGIALEFLLELFQTFKQEKGIAYLIQALKKGGLESKLMDFFPPNKRTEEYFKQVFLDKELNEIVKLHKAQASQEAKRELQQALIDDINDEKPYNEITSDIKDFSQRTNIPDHEIIVIIWSTIMSLGEWNKKEELVTDQAVRHLKNYCPLLQAFASTDRSELALILKVQEFCYENMNFMKAFQKIILLFYKTEVLSEEIILRWYKEGHSNKGKMHFLEQMRKFVEWLQSAEEESESEDEQKNGE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .** ::*.*:***:*******:*::**: *::.:: ** :* *** ::*:**::* *******.*.*****:***:*.***::::* **. *:* * *.:*:*: . *** *********** **:*: *:***:***: *** *** :*.: *.**.: ..:* * **:*:*:*:: * ::**::: :**.* : :*:* .::.:**::**.**:: *:*.: * : *:*: . : * : *::***: * :::. .. ::* ::: ::..*.: :* *:*:::** *********::**::***:*.*** **:: . ***:*:**:**:**:*::********::*:**::***** **:**.:.* *** *****:******:.******** *: : ", "identical_positions": 205, "similar_positions": 140, "identity": "48.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3955", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P27008-1", "uniprot_id": "PARP1_RAT", "id": "P27008-1", "name": "Poly [ADP-ribose] polymerase 1", "aln": "MAEATE-RLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRQPDTEVDGFSELRWDDQQKVKKTAE-AGGVAG-KGQHGGGGKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQMRLSKKMLDPEK-PQLGMIDRWYHPTCFVKNRDELGFRPEYSASQLKGFSLLSAEDKEALKKQLPAVKSEGKRKCDEVDGIDEVAKKKSKKGKDKESSKLEKALKAQNELVWNIKDELKKACSTNDLKELLIFNQQQVPSGESA-ILDRVADGMAFGALLPCKECSG-QLVFKSDAYYCTGDVTAWTKCMVKTQNPSRKEWVTPKEFREIS-YLKKLKIKKQDRLFPPESSAPAPPAPPVSITSAPTAVNSS------APADKPLSNMKILTLGKLSQNKDEAKAMIEKLGGKLTGSANKASLCIS-TKKEVEKMSKKMEEVKAANVRVVCEDFLQDVSASAKSLQELLSAHSLSSWGAEVKVEPGEVVVPKGKS-AAPSKKSKGAVKEEGVNKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLESDKESRYWIFRSWGRVGTVIGSNKLEQMPSKEDAVEHFMKLYEEKTGNAWHSK-NFTKYPKKFYPLEIDYGQDEEAVKKLAVKPGTKSKLPKPVQELVGMIFDVESMKKALVEYEIDLQKMPLGKLSRRQIQAAYSILSEVQQAVSQGSSESQILDLSNRFYTLIPHDFGMKKPPLLNNTDSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEVIRKYVKNTHATTHNAYDLEVIDIFKIEREGESQRYKPFRQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTAPDPSAS-ITLDGVEVPLGTGIPSGVNDTCLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11103-1", "uniprot_id": "PARP1_MOUSE", "id": "P11103-1", "name": "Poly [ADP-ribose] polymerase 1", "aln": "MAEASE-RLYRVQYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGQSIRHPDVEVDGFSELRWDDQQKVKKTAE-AGGVAG-KGQDGSGGKAEKTLGDFAAEYAKSNRSMCKGCLEKIEKGQMRLSKKMVDPEK-PQLGMIDRWYHPTCFVKKRDELGFRPEYSASQLKGFSLLSAEDKEALKKQLPAIKNEGKRKGDEVDGTDEVAKKKSRKETDKYS-KLEKALKAQNELIWNIKDELKKACSTNDLKELLIFNQQQVPSGESA-ILDRVADGMAFGALLPCKECSG-QLVFKSDAYYCTGDVTAWTKCMVKTQNPSRKEWVTPKEFREIS-YLKKLKVKKQDRIFPPESSAPITVHWPLSVTSAPTAVNSS------APADKPLSNMKILTLGKLSQNKDEAKAVIEKLGGKLTGSANKASLCIS-IKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQDLLSAHSLSPWGAEVKAEPGEVVAPRGKS-AAPSKKSKGCFKEEGVNKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKESRYWIFRSWGRLGTVIGSNKLEQMPSKEEAVEQFMKLYEEKTGNAWHSK-NFTKYPKKFYPLEIDYGQDEEAVKKLTVKPGTKSKLPKPVQELVGMIFDVDSMKKALVEYEIDLQKMPLGKLSRRQIQAAYSILSEVQQPVSQGSSESQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEVIRKYVKNTHATTHNAYDLEVIDIFKIEREGESQRYKPFRQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLIMLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSAS-ITLEGVEVPLGTGIPSGVNDTALLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09874-1", "uniprot_id": "PARP1_HUMAN", "id": "P09874-1", "name": "Poly [ADP-ribose] polymerase 1", "aln": "MAESSD-KLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRHPDVEVDGFSELRWDDQQKVKKTAE-AGGVTG-KGQDGIGSKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEK-PQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDS-KLEKALKAQNDLIWNIKDELKKVCSTNDLKELLIFNKQQVPSGESA-ILDRVADGMVFGALLPCEECSG-QLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKEWVTPKEFREIS-YLKKLKVKKQDRIFPPETSASVAATPPPSTASAPAAVNSS------ASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLTGTANKASLCIS-TKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSPWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGINKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSK-NFTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSAN-ISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RHR0-1", "uniprot_id": "PARP1_DANRE", "id": "Q5RHR0-1", "name": "Poly [ADP-ribose] polymerase 1", "aln": "MADSQDDKLYKAEYAKSGRASCKKCKDNIAKDSLRMAIMVQSPMFDGKVPHWHHFSCFWLR-AAVQSP-SDISGFTDLRWDDQEKVKTAIE-SGGATGGKGGQKGAAKGEKTLNDFAVEYAKSNRSTCKGCDQKIEKDQIRVSKKTVDPEK-PQLGLIDRWYHTGCFVSRREELIFKPEYSAAQLKGFAVLRDEDKEELKKRLPAVKSEGKRKADEVDGG--VSKKQKKEDE-----KLEQNLKDQSQLIWGIKDKLKKFCSINDMKELLIANSQEVPSGESN-IVDRLSDCMAFGSLKPCETCKG-QLVFKSDAYYCTGDISAWTKCVFKTQTPDRKDWVTPKEFSEIP-FLKKFKFKRQDRVFPKDAPPAAATPSSGSTTSAATSVSSASKNLTEAPADKPLTGMKLLAVGKLSKNKDDLKKFVEDLGGKITGTASKAALCIS-SKKEIEKMSKKMEEVRDAGVRVVADDFLTDIKESGKALQELISLHAISPWGAEVKVEAP-AAAAATKSTGAHSSKSTGKVKEEEGGSKSKKMKLTVKGGAAVDPDSGLENCAHVLEQNGKIYSATLGLVDIVRGTNSYYKLQLLEDDVQKRYWVFRSWGRVGTTIGGNKLDKFYDKNSAMDNFCGVYEEKTGNAWASS-NFTKYPNKFYPLEIDYGQDEEAVKKLTQSAGAKSQLEKPVQDLIRMIFDVESMKKAMVEFEIDLQKMPLGKLSKRQIQSAYSLLSEVQQAVADSSSESLILDLSNRFYTLIPHDFGMKKPPLLSNVDYIQQKVQMLDNLLDIEVAYSLLRGGVENNEKDPIDINYEKLKTKIEVVDKSSHEAQLILQYVKNTHAATHNTYTLDVEEIFKIEREGEYQRYRPFKELPNRQLLWHGSRTTNYAGILSQGLRIAPPEAPVTGYMFGKGVYFADMVSKSANYCHTSQADPVGLILLGEVALGNMHELKKASHITKLPKGKHSVKGLGRSAPDPRAT-VSLNGVDIPLGKGMNTNIDDTSLLYNEYIVYDVSQVNLKYLLKIRFNYQTSLW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35875-1", "uniprot_id": "PARP1_DROME", "id": "P35875-1", "name": "Poly [ADP-ribose] polymerase 1", "aln": "MDIELP---YLAEYARTGRATCKGCKSTISKDTLRIAVMVQSAFHDAKVPNWFHKTCFFKN--QRPSSVGDIQNIGNLRFADQKELTDLVENIQEVISAQLGKKRSKAFNLALKDFGIEYAKSSRSTCRGCEQKINKDLVRLRKTVYDTEVGMKYGGQPLWHHLECFAQLRSELGWF--ASGEDMPGFQSLADDDQAKVKNAIPPIKSE--ELPDTKRAKMELSDTNEEGEK-------KQRLKDQNDAYFRFRDDIKNKMKKKDIDILLKFNNQQPVTGDTEKLFDQTADLLTFGAIESCSECNSCQFIVNKSGYICNGNHSEWTKCNKLLKEPTRSACIVPKELKALYNFLNTVKEIPSTRIFNNFPPNKSTFSRSLLKTNKNNDVLVRP---TIPRISPPLYNLKFSIIGLKNQHK-ELRKRIENLGGKFEVKISENTIAIISTELEIQKKSTRMKFAEELGIHIVPIEFLDFVEADTEGAIKYINSTCICSWGTDPKSRIPKETTKSLNS-NSIYTKSMPVSR-----------TFKVKDGLAVDPDSGLEDIAHVYVDSNNKYSVVLGLTDIQRNKNSYYKVQLLKADKKEKYWIFRSWGRIGTNIGNSKLEEFDTSESAKRNFKEIYADKTGNEYEQRDNFVKRTGRMYPIEIQYDDDQKLVKHESHFF--TSKLEISVQNLIKLIFDIDSMNKTLMEFHIDMDKMPLGKLSAHQIQSAYRVVKEIYNVLECGSNTAKLIDATNRFYTLIPHNFGVQLPTLIETHQQIEDLRQMLDSLAEIEVAYSIIKSEDVSDACNPLDNHYAQIKTQLVALDKNSEEFSILSQYVKNTHASTHKSYDLKIVDVFKVSRQGEARRFKPFKKLHNRKLLWHGSRLTNFVGILSHGLRIAPPEAPPTGYMFGKGIYFADMVSKSANYCCTSQQNSTGLMLLSEVALGDMMECTSAKYINKLSNNKHSCFGRGRTMPDPTKSYIRSDGVEIPYGETITDEHLKSSLLYNEYIVYDVAQVNIQYLFRMEFKYSY---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * .:**::***:** *...*.**:**:*:****.:.*.***:*.* :**: . ::..: :**: **:::. * . . : . . : :* **. *****.** *:** :**:*. :*: *. *.* : * *:* **.. *.** : *. :: ** * :*: :*: :* :*.* . * . ::..:.. :: ** *.: : ::*.:*: . :*:. ** *.*: :*:: :.*: :* :.**:: .*. *.. *::.:...* *.*: : **** : * *. :.***: : :*:..* . *:* .. . . :. * . . ** .:*: :* .::* : : :*.****: . .: ::.* : *::* ..:*: .. .:::* :** :. . :. . : :..**:: * . .. :* : .** : .:.:*.* *********. *** ...: :*..***.** :..*****:***: * :.:**:******:** **..**::: .:.* :* :* :**** : . **.* . ::**:**:*.:*:: **: : .*:* .**:*: :***::**:*:::*:.**::******** :***:** ::.*: : : .*. : ::* :*********:**:: *.*:.. : :: :***.* :******:::. .. :*:* :* ::**.: .:*:.*.* .:: :*******:**::* *.: ::**:.*:** :*::**::* **:******* **:.****:********** ********:************* *** :. **::*.*****:* * . *.:*.**.:.*** * *:: *** . : :**::* * : .:.**********::***::**:::.*::. ", "identical_positions": 362, "similar_positions": 355, "identity": "35.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3958", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P2K6-1", "uniprot_id": "P4R3A_MOUSE", "id": "Q6P2K6-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3A", "aln": "-----------------------MTDTRRRVKVYTLNEDRQWDDRGTGHVSSGYVERLKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVDITQDLVDESEEERFDDMS--SPGLELPSCELSR-----LEEIAELVASSLPSPLRREKLALALENEGYIKKLLELFHVCEDLENIEGLHHLYEIIKGIFLLNRTALFEVMFSEECIMDVIGCLEYDPTLSQPRK-HREFLT-KTAKFKEVIPISDPELKQKIHQTYRVQYIQDMVLPTPSVFEEN-MLSTLHSFIFFNKVEIVGMLQED--EKFLTDLFAQLTDEATDEEK------RQELVNFLKEFCAFSQTLQPQNRDAFFKTLSNMGILPALEVILGMD-DTQVRSAATDIFSYLVEYNPSMVREFVMQEAQQNDD-------------DILLINLIIEHMICDTDPELGGAVQLMGLLRTLVDPENMLATANKTEKTEFLGFFYKHCMHVLTAPLLANTTEDKPSKDDFQTAQLLALVLELLTFCVEHHTYHIKNYIINKDILRRVLVLMASKHAFLALCALRFKRKIIGLKDEFYNRYIMKSFLFEPVVKAFLNNGSRYNLMNSAIIEMFEFIRVEDIKSLTAHVIENYWKALEDVDYVQTFKGLKLRFEQQRERQ-DNPKLDSMRS----ILRN-HRYRRDARTLEDEEEMWFNTDEDDMED--------------------GEAVVSPSDKTKNDDDIMDPIS--------------------------------------------------KFMERKKLKESEEKEVLL-KTNLSGRQSP----------------------SFKLSLSSGTKTNLTSQSSATSLPGSPGSP-----------------------------------GSP--------------------------GSPGSPGSVPKSTSQTAAITTKG-GLVGLVDYPDDDEDDDEDED---KEDTLPVSKKAKFES-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AS21-1", "uniprot_id": "A0A8I6AS21_RAT", "id": "A0A8I6AS21-1", "name": "SMEK homolog 1", "aln": "-----------------------MTDTRRRVKVYTLNEDRQWDDRGTGHVSSGYVERLKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVDITQDLVDESEEERFDDMS--SPGLELPSCELSR-----LEEVAELVASSLPSPLRREKLALALENEGYIKKLLELFHVCEDLENIEGLHHLYEIIKGIFLLNRTALFEVMFSEECIMDVIGCLEYDPTLSQPRK-HREFLT-KTAKFKEVIPISDPELKQKIHQTYRVQYIQDMVLPTPSVFEEN-MLSTLHSFIFFNKVEIVGMLQED--EKFLTDLFAQLTDEATDEEK------RQELVNFLKEFCAFSQTLQPQNRDAFFKTLSNMGILPALEVILGMD-DTQVRSAATDIFSYLVEYNPSMVREFVMQEAQQNDDVSKKLTEQKITSKDILLINLIIEHMICDTDPELGGAVQLMGLLRTLVDPENMLATANKTEKTEFLGFFYKHCMHVLTAPLLANTTEDKPSKDDFQTAQLLALVLELLTFCVEHHTYHIKNYIINKDILRRVLVLMASKHAFLALCALRFKRKIIGLKDEFYNRYIMKSFLFEPVVKAFLNNGSRYNLMNSAIIEMFEFIRVEDIKSLTAHVIENYWKALEDVDYVQTFKGLKLRFEQQRERQ-DNPKLDSMRS----ILRN-HRYRRDARTLEDEEEMWFNTDEDDMED--------------------GEAVVSPSDKTKNDDDIMDPIS--------------------------------------------------KFMERKKLKESEEKEVLL-KTNLSGRQSP----------------------SFKLSLSSGTKTNLTSQSSATSLPGSPGSP-----------------------------------GSP--------------------------GSPGSPGSVPKSTSQPAAITTKG-GLVGLVDYPDDDEDDDEDED---KEDTLPVSKKAKFES-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6IN85-1", "uniprot_id": "P4R3A_HUMAN", "id": "Q6IN85-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3A", "aln": "-----------------------MTDTRRRVKVYTLNEDRQWDDRGTGHVSSGYVERLKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVDITQDLVDESEEERFDDMS--SPGLELPSCELSR-----LEEIAELVASSLPSPLRREKLALALENEGYIKKLLELFHVCEDLENIEGLHHLYEIIKGIFLLNRTALFEVMFSEECIMDVIGCLEYDPALSQPRK-HREFLT-KTAKFKEVIPISDPELKQKIHQTYRVQYIQDMVLPTPSVFEEN-MLSTLHSFIFFNKVEIVGMLQED--EKFLTDLFAQLTDEATDEEK------RQELVNFLKEFCAFSQTLQPQNRDAFFKTLSNMGILPALEVILGMD-DTQVRSAATDIFSYLVEYNPSMVREFVMQEAQQNDDVSKKLTEQKITSKDILLINLIIEHMICDTDPELGGAVQLMGLLRTLVDPENMLATANKTEKTEFLGFFYKHCMHVLTAPLLANTTEDKPSKDDFQTAQLLALVLELLTFCVEHHTYHIKNYIINKDILRRVLVLMASKHAFLALCALRFKRKIIGLKDEFYNRYIMKSFLFEPVVKAFLNNGSRYNLMNSAIIEMFEFIRVEDIKSLTAHVIENYWKALEDVDYVQTFKGLKLRFEQQRERQ-DNPKLDSMRS----ILRN-HRYRRDARTLEDEEEMWFNTDEDDMED--------------------GEAVVSPSDKTKNDDDIMDPIS--------------------------------------------------KFMERKKLKESEEKEVLL-KTNLSGRQSP----------------------SFKLSLSSGTKTNLTSQSSTTNLPGSPGSP-----------------------------------GSP--------------------------GSPGSPGSVPKNTSQTAAITTKG-GLVGLVDYPDDDEDDDEDED---KEDTLPLSKKAKFDS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SP90-1", "uniprot_id": "PP4R3_DANRE", "id": "Q5SP90-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3", "aln": "-----------------------MTDTRRRVKVYTLNEDRQWDDRGTGHVSSAYVERLKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVDITQELIDESEEERFDDMS--SPGLELPPCELSR-----LEEVAELVASSLPSPLRREKLALALENEGYIRKLLELFRVCEDLENREGLHHLYDIIKGIFLLNRTALFEVMFSEECIMDVIGCLEFDPSLPQPRR-HREFLT-TTARFKEVIPISDPELRQKIHQTYRVQYIQDMVLPTPSVFEEN-MLSTLHSFIFFNKVEIVGMLQDD--EKFLTELFAQLTDEATDDDK------RHELVNFLKEFCAFSQTLQPQNRDAFFKTLSNMGILQALEVILGMD-DVQVRGAATDIFSYLVEYNPSMVREFVMQESQQNDD-------------DILLINLIIEHMICDTDPELGGAVQLMGLLRTLVDPENMLATANKTEKTEFLSFFYKHCMHVLSAPLLANTTEEKPSKDDFQTCQLLALIVELLTFCVEHHTYHIKNYIINKDILRRVLVLTASQHAFLALCALRFMRKIIGLKDEFYNRYIMRNFLFEPVVKAFLNNGSRYNLINSAIIEMFEYVRVEDVKSLTAHIIENYWKGLEDVDYVQTFKGLKLRYEQQRERQ-DNPKLDSMRS----ILRN-HRFRRDARTLEDEEEMWFNTDEEDLED--------------------GEAVVPPSDKMKNDEDLMDPIS--------------------------------------------------KFMERKKLKDSEEKEVLTGKASLSGRQSP----------------------SFKLSFSSSPKASLSSPPTASLHPGSPGSP-----------------------------------SSP--------------------------GTG------ARSSPPSAAVTTKG-GLVGLVDYPDDDEEDEDEEDADSKEESPPLSKKSKLSS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFS5-1", "uniprot_id": "PP4R3_DROME", "id": "Q9VFS5-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3", "aln": "----------------------MTTDTRRRVKLYALNAERQWDDRGTGHVSSTYVERLKGISLLVRAESDGSLLLESKIQPDTAYQKQQDTLIVWSEGDNFDLALSFQEKAGCDEIWEKICQVQGKDPSVEITQDIVEESEDERFEDMSDTAPPIELPPCELSR-----LEDISETIQSCLSTPLRKEKLSMALESESYIKKLLNLFHVCEDLDNTEGLHHLFEIFKNIFLLNKNALFEIMFADDTIFDVVGCLEYDPSVSQPKK-HRQYLK-QLAKFREAVPIKNLDLLAKIHQTFRVQYIQDIILPTPSVFVEDNMLNTLSSFIFFNKVEIVTMIQDD--ERYLLDVFAVLTDPTTGDAK------RRDTVLFLKEFCNYAQNLQPQGKDSFYKTLTCLGILQALELTLVMN-DKKTKSASIDILTAIVEFSPLVVRNYTLNQANRPEV-------------ERMLLNIAIEQMLNDSEPELGIAVQLMGIVKILLEPENMLT-----EKGDFLNFFYKYSVQTLVAPVILNTIGDRPQNEDYQTAQLLGIVLDILSFCVEHHSYHIKNFLLQKDLLKRILVLMKSTHTFLVLGALRLLRKIIALKDEFYNRHIVKCNLFAPVVDAFIRNNGRYNLLESAILELFEFIKLEDIRTLCVYFVENFSKIFDEIEYVQTFKYLKNRYDQYQDRLKDRDKMENRTDGGLPIIRSGGRFRRDQRQMEEEEEMWFNEEDDFTEEIDTYNNVMKSVSEKNGPQTQNQQKSSPPHSTSPHSGLLGSLSTTASSTATSATSGAPVASGSSSPEAISADEQTQAAVHLAAAALQHHQQQQQQQQQNPFQQQTQPEIAELQQQLSSVEAPQSQELELSQSAAASASPTSSSSSLEASTSSSSASSSSSSSSSSSPPGSSAAASLCDSATVAAVAASQFLSTIATAMAASVTAAAATNSSPSISPAPAVSSPDIENADAQLPPSDDASSPASGEQDANSTEGTSSEADKTTAKKGLVDYESDSGEDDYEEDE--YSEGPQAQKRARQA--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40164-1", "uniprot_id": "PP4R3_YEAST", "id": "P40164-1", "name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3", "aln": "MSLPGTPTTSPTPMDEDTEQAVSVNTEPKRVKVYILENN-EWKDTGTGFCIGEVDEGKFAYLVVSDEDSPTETLLKSKLEGNIEYQRQEETLIVWKDLGGKDIALSFEESMGCDTLCEFIVHVQR-NIESNISLVTVKSSDNGLGSVHDIITGPVTLPSNDQQQNSQTLLEALKILNENTSFDFLKNETIEFILQSN-YIDTLISHFHKAEEEKIPKDLFLLSNIIKTLILYNKRDILESMVEDDRIMGIVGILEYDTEYPTSKANHRKYLGSKGPNFKEVIPLENEDLKIIMKKCFRLQFLKDVVLVR---FLDDHNFNLISEIVMDLETCIIDFLQVGTFLDRLIELYDTKTLPESSSEKEKFVQKRKDGIRLLQQCVQMSINLDAVDRSKFYKTLVRKGLFKVLDYAFHMETDSNVRILATDTIITIIEHDILLIHNVQNEDSFKRQH--------------KSAPDDKSSHRKYPQDYSSSTDSKLLLILSTILLSDRSPGLREQVVQALNTLLHPEGCVGNGEGSYDLMGRSNYEAKN-------TSEDFPSFSYGLNSDSINLNNYHYSSDEMNNLEPESESEFQVMEYFANFYNKIAPILFGPLIKKDITT---EMAEIDGQIEKVTKDDLLLIHLVKLVSFVCTEHDRVLSRRFILENGILDSVSKLIGGNHMMQLRLTAVRCIK-NLMCLDDKYYHRYMISKN---LYAPVFKLFQENIDKNNLANSCIQDFFR--------------IIITECRAYQSDGHNRKEKTNGSYD-------------------------------------------------GNGNDVKTNVNNNRTNFTILNKYLVQTYGD----------------------VLRKATDIPFIQDMLETGEENQPDHSSFEN---------------------------------------------------------------SIEGGNDISVNMSTDGFASNHLEDIDIKNVKRLHSEIEHFENDPHYSGDQLAFKKSVDQMNAST", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :***:* *: : :*.* ***. . * . :: :* . **:**:: : **:*::*****.: . *:****:*. *** : * * :** : . :*: :..*:: . . : : **. : .: ** : . *:.*.: : *:.: ** .*:. *: .*: . :.*. * :*:* ::* *: ::* *. :: *:.::* **:*. . .: **::* ..*:*.:*:.: :* ::: :*:*:::*::* * :: :. : .::: :. *: ::* . * ::: * :.. * *:: : :*:: : .*:. .:. *:*** *:: .*: : *: * :.: : * : ::*.. :::: ::: : : : .: : . . :*: :: :: .:. : :. : .: .. : :: . . ::: :: .: :::*: ..* :..: * . .: * : * . : :: * . :.. :.: : :*: ::::..:: *. : * .: : . . : : :: * : : ::. * :. : :*: * :. :: : .. . .. .. . : : : :. . :. : * . :. : . . . . *. .: :: : .: .: . : : . . . ", "identical_positions": 110, "similar_positions": 303, "identity": "10.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3967", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60941-1", "uniprot_id": "DTNB_HUMAN", "id": "O60941-1", "name": "Dystrobrevin beta", "aln": "MIEESGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIYYQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYTEHSVRTCFPQQRKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNYQLCQNCFWRGHAGGPHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPTR-EPPHPVFPEQPEKPLDLAHIVPPRPLTNMN-DTMVSHMSSGVPTPTKRLQYSQDIPSHLADEHALIASYVARLQHCAR-----VLDSPSRLDEEHRLIARYAARLAAEAGN-VTRPPTDLSFNFDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEELMKLLKEEEQKQAAQATGSPHTSPTHGGGRPMP-----------------------MP--VRSTSAG-------STPTHCPQ-----DSLSGVGGDVQEAFA------------------------------QGTRRNLRNDLLVAADSITNTMSSLVKELHSAE----------------------------EGAEEE-EEKMQNGKD-RG-----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O70585-1", "uniprot_id": "DTNB_MOUSE", "id": "O70585-1", "name": "Dystrobrevin beta", "aln": "MIEEGGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHSTEISVSRLETVISSIYYQLNKRLPSTHQISVEQSISLLLNFMVAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSNGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVRTCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHASGAHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPSR-EPPHPVFPEQPEKPLDLAHLVPPRPLTNMN-DTVVSHMSSGVPTPTKRLQYSQDMPNLLADEHALIASYVARLQHCTR-----VLDSPSRLDEEHRLIARYAARLAAEAGN-MTRPPTDASFNFDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPMLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLK-------AQATGSPHTSPTHGGGRPMP-----------------------MP--VRSTSAG-------STPTHGPQ-----DSLSGVGGDVQEAFA------------------------------QGTRRNLRNDLLVAADSITNTMSSLVKELHSGA----------------------------EAEEQAGTEKTREGLPPRGTFLSVFLLHTWTKLAGCQTHS-----------------------TSRERSQAYGKWGGTA-----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2BFU1-1", "uniprot_id": "A0A8M2BFU1_DANRE", "id": "A0A8M2BFU1-1", "name": "Dystrobrevin", "aln": "MIEE-GRKAGVMADRKQLFMDMKTQNYDTIRLSTYRTACKLRFVQKKCNLHLVDVWNMIEAFRDNGLNTLDVCTEISVARLETILTCIYQQLNKRLPTTHQISVQHNTSLLLNFMATAHDTDAQGRLTVFSVKMMLSVLCGGKLVDKLRYIFSQISDSHGAMEMSKFDHFLREALKLPAAVFEGPSFGYLDHLARSCFPQQKKVMLNMFLDALMSDPPPQCLIWLPLVHRMGNVENVHHPVSCSFCRSDGMTGFRYRCQQCFNYQLCQNCFWRGHASGNHSNHHDMKEHSSWKSPAKKLGRAISKSLGCVPSR-EPSHPIYPEYPEKPLNLSNIVPPRPIGNMN-EPAP-PLSTGS-SPTKRLP-TLAAAQRMNEEHALIAAYVNKLQSSPR-----ALDSPVRSDEEHKLIARYASRLATDPGH-TARP---ADFSYDTNKQQRELIMQLENKNREILQEIQRLRVEHEQACQPTPERVQQNPTLLAELRQLRQRKDELEQRMSSLQESRRELMVQLEGLMKLLKDEEQRQAAQAAGS---SPSHASPRSMP-----------------------MP--IRSPSSGPAPTYTGHTPTHGPQ-----DSLAGVGGDVQEAFS------------------------------QGPRRNLRNDLLVAADSITNTMSSLVKELNSAE----------------------------DGDEDE--RLLQNGKD-RG-----------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8DYB7-1", "uniprot_id": "A8DYB7_DROME", "id": "A8DYB7-1", "name": "", "aln": "---------MELEPRVAILQDLRLQTFDSIRFASYRTASKLRYIQKSTNLHLVDIWNVIEAFRENGLNTLEPQSEVSVARLETLVSSLYHNLNKRLPTAQQVPVDSKAGLLLNWLLAAYTSDNSGKIRVFSIKVALATMCSGKLVDKLRYIFSQISDGAGQLVAWKLGEFLREVLALPAAVYESPTFHYKEGLEEEIFPAENKVTVNDFMATLMSEPGPSCLVWLPLVHRLATVETIVHPTVCSVCHKENFTGFRYRCQRCHAYQLCQECFWHGKTSLNHQNDHEVKEYSSYKSPSKQIGHSLRKSFRCVPEKTVQVLPRFPDQPEKTLNLSHIVPPSPLPSHNGFSDPSGLVHGHHGPHPGLPGQHGLFDRSSTLDSRATGRSLDSASGTAGTTMSRVAAASANDEEHRLIARYAARLAQENRAPSNLPDNATPIGTDNSRAQRELIAQLESKNKEIMREIARLRRQQE-----TEQMAPENPALINELRALRQRKGELEGHLGALQDSRRQLMEQLEGLMRMLKNQ---QTASPRSTPNSSPRSGKSPPMPGGAGILGTSPMSALHAQQMQQHPMAGGVRASQQQLLQQQQQQAHGHGPFSQSQLEQLNQISSDMRSAFAANGSATPPPMRTTTATANVSAIPSLNPISNQNPNLNPDAELNEAADHLTSAISHMVSDLNAGRGRAQQLGPQPASSIPQARFIMPLEFRHIEGGESEDSSQCECNDCECGEYEEVFRTDEDLECEGAAAPFGNAYSLFPTSGVHEEDHFDYTFGQGEELSQVNRILGYRNHPELFIDDEQAGFPALHEIGETIDELQLIMHAYIMKYSLNI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: ::: *.:* **:::****.***::** ******:**:*****:******: :*:**:****:::.:* :******:::*:.*: . .****:: :*: :: *:: ***:* *:.:*.**::*****:***:**. * : *:..**:*.* **:**:*.*:* * : . ** :.*: :* *: ::*::* *.**:****:**:. **.: **. ** *: :.: *******:*. *****:***:*::. *.*.*::**:**:***:*::.::: **: *** : * :*: ***.*:*:::*** *: . * . : * * * . .: :. . : :. ****:******:*** : * :. * .: **:** :**.**:**::** *** ::* * : . :** *: *** *****.*** ::.:**:***:** *** **::** *.. .: ** . .** *. :*:.. : * * :.* :..*::.**: *... * :* *** :*.::* :*.:*::. :. *. . . * ", "identical_positions": 242, "similar_positions": 197, "identity": "29.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3973", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZZZ0-1", "uniprot_id": "A0A8I5ZZZ0_RAT", "id": "A0A8I5ZZZ0-1", "name": "ATP-dependent RNA helicase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MRRQTEATKRKHQVSSDAPPAKRRNEISSLSAKKASNKETQR---AFKGSAHKTFPPKKHLDTIGNERQEEK--PCVKTSSLFKNNPE---------------------------------------------------------------------IPELHRTVVKQAREQVFSPEAFQELDLHPHLISTINTVLKMSSMTSVQKQSIPVLLE---GRDALVRSQTGSGKTLAYCIPVVQSLQALTSKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKSTKNIHFNR---VRWLVVDEADRILDLGFEKDVTVILNAVN----------AECQKRQNVLLSATLTEGVTRLADISLHNPVSISVLDKSWDQPNPKE--------------------VASIQLDSFAIPESLDQYVVLVPSKLRLVCLAAFILKKCKFE-------KDQKMIVFFSSCELVEFHYNLFLHTLLC---------HSGTPASETLPSASWPLK----FLRLHGNMKQEERTSVFHEFS------HSGTGVLLCTDVASRGLDLPQVTWIVQYSAPSAPAEYIHRIGRTARIGCHGSSLLILAP-SEAEYVNSLA-SHKINVSEIKLEGILAVLAKDDCFKRR---------QRGAQRSHATGPQEIRERATVLQTVFEDYVHSSQRMVSWAKKALQSFIRAYATYPKELKSIFHVRSLHLGHVAKSFGLRDAPRNLG-------VSAVR--KASFKRPDPRRKTQRKHHLVPAEVLHSEHSSGLEGNGTKGRKQG--------------LRVAP------------SKPGLRR----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NZQ2-1", "uniprot_id": "DDX31_MOUSE", "id": "Q6NZQ2-1", "name": "ATP-dependent DNA helicase DDX31", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MKRQAEATKRKHQVSSDAPPAKRRSEISSVLAKKASDKETQR---TFKGSTHKTFPPKKYLDSIGNGRQEEK--PCIKTSSLFKNNPE---------------------------------------------------------------------IPELHSTVVKQAREQVFSPEAFQELDLHPHLISTINTVLKMSSMTSVQKQSIPVLLE---GRDALVRSQTGSGKTLAYCVPVVQSLQALTSKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKSTKNLHFNR---IRWLIVDEADRILDLGFEKDITVILNAVN----------AECQKRQNVLLSATLTEGVTRLVDISLHNPVSISVLDKNCNQPNPKE--------------------VASIQLNSFAIPESLDQHVVLVPSKLRLVCLAAFILQKCKFE-------KNQKMIVFFSSCELVEFHYSLFLHTLLC---------HSGTPTSEHLPSASWPLK----FLRLHGNMEQEERTSVFHEFS------HSETGVLLCTDVASRGLDLPQVTWIVQYSAPSSPAEYIHRIGRTARIGCHGSSLLILAP-SEAEYVNSLA-SHKINVGEIKMEDILAVLAKDDCFKRR---------QRGAQKSRASGPQEIRERATVLQTVFEDYVHSSQRMVSWAKKALQSFIRAYATYPKELKSIFHVRALHLGHVAKSFGLRDAPRNLS-------VSAVK--KASLKRPHPRRKTQRKQHLVPAEVLHSEHSSGLEGGATKCRKQGK----------QQGLQVAP------------SKPGPWRE---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H8H2-1", "uniprot_id": "DDX31_HUMAN", "id": "Q9H8H2-1", "name": "ATP-dependent DNA helicase DDX31", "aln": "-----------------------MAPDLASQRHSESFPSVNSRPNVILPGREGRREGLPPGGGTRGSLVPTRPVPPSPAPLGTSPYSWSRSGPGRGGGAGSSRVPRGVPGPAVCAPGSLLHHASPTQTMAAADGSLFDNPRTFSRRPPAQASRQAKATKRKYQASSEAPPAKRRNETSFLPAKKTSVKETQR---TFKGNAQKMFSPKKHSVSTSDRNQEER--QCIKTSSLFKNNPD---------------------------------------------------------------------IPELHRPVVKQVQEKVFTSAAFHELGLHPHLISTINTVLKMSSMTSVQKQSIPVLLE---GRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKSTKNIHFSR---LRWLVFDEADRILDLGFEKDITVILNAVN----------AECQKRQNVLLSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDK-----------AVQEVCPPPAGDKLDSFAIPESLKQHVTVVPSKLRLVCLAAFILQKCKFE-------EDQKMVVFFSSCELVEFHYSLFLQTLLS---------SSGAPASGQLPSASMRLK----FLRLHGGMEQEERTAVFQEFS------HSRRGVLLCTDVAARGLDLPQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAP-SEAEYVNSLA-SHKINVSEIKMEDILCVLTRDDCFKGK---------RWGAQKSHAVGPQEIRERATVLQTVFEDYVHSSERRVSWAKKALQSFIQAYATYPRELKHIFHVRSLHLGHVAKSFGLRDAPRNLS-------ALTRKKRKAHVKRPDLHKKTQSKHSLA--EILRSEYSSGMEADIAKVKKQNAPGEPGGRPL-QHSLQPTPCFGRGKTLKWRKTQKGVQRDSKTSQKV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6R7-1", "uniprot_id": "A0ACD6B6R7_DANRE", "id": "A0ACD6B6R7-1", "name": "ATP-dependent RNA helicase", "aln": "-------------------------------------------------------------------------------------------------MAEDTLMLN-------ISSGSVQFNRKTNQKHLSSSEKWAQKKRVAKRKAAVEPQESSASKQRKINQTGQQHAQKQTLQTPRSPSQRSNNRDTEENPVQRENSEAKSPSKVKTFPKKAPTEHEDHGRPFIKTSSLFRNNPE---------------------------------------------------------------------IPDVLSPAVNQVKEKVFTSNTFEELNLHPHLVATLHKVLNVSSMTSVQKQTIPVLMS---GKDAVVRSQTGSGKTLAYGIPMVQFLQAIQPKVKRSDGPLAVVIVPTRELALQSFQMFQKLLRPFTWIVPGVLMGGEKKKAEKARLRKGINVLISTPGRLVDHIKNTLSIAFSA---VRWLILDEADRILDLGFEKDLTVILNALN----------TAGPDRQNVLLSATITEGLSRLASISMKDPVSVHVSEGSEETVEACP------------------QAAPQALSDSYAVPERLQQHVVVVPSKLHLVCLAAFILAKCKFE-------QRQKLVIFISSCEAVEFLLNLFTAVLCE---------IPSNTSSK----STSCLN----FYRLHGNMRQEERTEVFQEFS------QCKTGILLCTDVAARGLDLPQVTWIVQYNPPVSAAEYVHRVGRTARIGAQGSSLLFLTP-SETAFVDVLA-NHNISLSEMKMVDILSTLMKDERFKGRG--------KWDSKRSADAFEQEVRERATLLQTDFENYVHASNESLQTAKSALQCFLRAYTTYPSSLKHIFHIRMLHLGHAAKSFGLRDAPQGLASSISTNPANSKHSKKAKDKAKSPPKKLTAKQRVS--NLMRSEYDSGMDGQSKAKKKRK-------------------------------NKKGQAEESTDA-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86B47-1", "uniprot_id": "Y8611_DROME", "id": "Q86B47-1", "name": "Probable ATP-dependent RNA helicase CG8611", "aln": "MVENISLNVTVKSSARKNQQQSPALSVKKRAQKSQDFDFQFNVDKPKVKAIVVRRRAPPSKVEPTNSSVPNTTKSPTPSVSSSKSAISTLSASPKANASNDDLMFNVSPTKPPVKSVLGDDFMLNVTTKPVVAQKAKPKITRAERLGKKQRQGKPLTKLSEEQITRALKSNKKPKNPNQLPTPGDLFRAQLEEERRQKRREEGGGDQEASADEEDAKNNSGGGSPRVKPSSAVKESKKSSDIEDSGESGEESATSDEEPDESSAQSPGQEKEPKQTAKKPPKAEETSSTNRFRTKKIGLFDQSDVEALKQLGQRAVKPVKETIFTGSKISTLGLHPHAVKNLEDLLSIRELTSVQQKTIPEVLQ---GKDVLVRSQTGSGKTLAYALPLVELLQKQQPRIQRKDGVLALVIVPTRELVMQTYELIQKLVKPYTWIVPGSLLGGESRKSEKARLRKGINILIGTPGRLVDHLLHTASFKLTK---LQFLILDEADRLLELGYERDVKQLVEAIDKQRAECE--DKELPQLQRMLLSATLTSQVQQLAGLTLKNPLYIDNSDEAASAALKSKDGYQKETIEALLEVDDGLGEYQEDVTGVLSIPENLQLSYVVVPPKLRLVALSSLLAKEVDASP------KQFKAIVFMSTTEMVNFHHDMLNEALTRRVLDEEDEQEKGDSDDDGDIPLLQGLR----FFKLHGSMTQTERQGVFRGFR------DCASCVLLATDVVGRGIDVPDIKLVVQYTPPQTTADFVHRVGRTARAGRKGRAVLFLTP-SEAQFVRHLE-KKRIRIQQGDMYAYLQTLLPKD-----------------------DEARTVQEAASNLQHKFQTLLEDDRELHDKSCKAFVSWMKFYSTFPKELKPIFNVRIAHMGHFAKSFALKEAPSKFAAKHAAPKAAPPTNRLTYTERDPEKIQAQKRAKRRFTTTVSGEVRQLQQRDVGAQKPGAPPPKGGFIGGGVGRSSFMKSLGKSRALNMSEFDSGLPPEGAAKRRKQA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36120-1", "uniprot_id": "DBP7_YEAST", "id": "P36120-1", "name": "ATP-dependent RNA helicase DBP7", "aln": "------------------------------------------------------------------------------------------------MSDEDSMLLN------------FTTNEDTAGSSYKQAAKVTGGRWKDRRRMKMKLEGKTVSRKRKANTTGDEGIIPGRGENSIKKLHKESSYSSEEQEKYKGRNAHNTQGRTLPADSQFVSSLFTSNREITTAVNTNIHDEN----------------------------------------------------------------------------VAINPSNAPLKGDQFASLGVSSLLVSHLEQKMRIKKPTSIQKQAIPQIIGNAGKNDFFIHAQTGSGKTLSYLLPIISTILNMDTHVDRTSGAFALVIAPTRELASQIYHVCSTLVSCCHYLVPCLLIGGERKKSEKARLRKGCNFIIGTPGRVLDHLQNTKVIKEQLSQSLRYIVLDEGDKLMELGFDETISEIIKIVHDIPINSEKFPKLPHKLVHMLCSATLTDGVNRLRNVALKDYKLISNGTKKDSD-------------------------------IVTVAPDQLLQRITIVPPKLRLVTLAATLNNITKDFIASGQQSKTLRTIVFVSCSDSVEFHYDAFSGSDGHHKNLTGDSVRLLTKGNTMFPCFSDSRDPDVVIYKLHGSLSQQMRTSTLQHFARDNEATKGKHLIMFCTDVASRGLDLPHVGSVIELDPPFAVEDHLHRVGRTARAGEKGESLLFLLPGEEEKYMDYIQPYHPMGWELLKFDKEILMPAFKDVNVNRNDKFIRKDEKSSKNKDVGDKEYEWDTNATTWHLNIERRVVGDSAFKNLAVKGFISHVRAYATHISQEKKFFNVKFLHLGHLAKSFGLRERPKAMG----------LQSSKDGNSEKKPTKENSKNKMFRMARMAEKQIASEFNY---------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : : : : : . .. . .. . .. : :. : *.: . : :. : : . **:*:::** :: .* .:::********:* :*::. : .::.*..* *:*:.*****. * :. ..*: ::** *:*** :*:******** *.:*.****::**: * : :::::.**.*::::**::. :. ::: :. . .:* ***:*. : :* .::::: : . *: * .:**.**:** *:: : . : : ::*.* : *:* . : . : :***.: * * .:: * . :::.***..**:*:*.: ::: .* : :.:**:***** * :* ::*:* * .* :: : : : .: : .: *: : :: : . . : ..: . :: *:*. . * :*::: *:** ****.*:: * :. . : . : . : ", "identical_positions": 117, "similar_positions": 203, "identity": "11.43%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-3982", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C5W1-1", "uniprot_id": "MAP1S_RAT", "id": "P0C5W1-1", "name": "Microtubule-associated protein 1S", "aln": "-----------------------------------------------------------------------------------------MAAVMAAPEPAEAPSS-----------LLLLVVGGECGCPGLLAYVLEELERGVRSWEDVDPDVCSLDEQLKAFVSRHSATFSSIVKGQRSLHHRGETLETLVLLNPSDKSLCDELRNLLMDPAPHKLLVLAGPCLEETGELLLQTGGFSAHHFLQVLGDKEVQDALASAP---AAPALTVSCPTFGDWALLGPAPG-------LRLRLNPPARLPSS-EGLRAFLEYVAESLEPPSPFELLEPPATGGFLRLARPCCYVFPGGLGDAAFFAVNGFTVLVNGGSNPKSSFWKLVRHLDRVDAVLVTHAGADSLPGLNSLLRRKLAEREAAAGPQGQ-HEERLRRLLSPALGVVFLNAREAGSRLR------GGEDEAVCARSLLRSLGIVPLPLQRGPQP-SCPTVLFEKLGVGRLELFVLHPPPG-------------------------------DPAAPACALLVWQPAAPGDKVVRVLFPGRTPPARLLDGLQRLQHLPCLRRPVVTTQDLEV------PSRANSQDSLA--------SRDS----------------------TRKEPVRGTVG-------------------------ATS-RSAVRREP-------ALATR------------------------------------------------------DQKKDTKPG---PTRSTVRDVRRSGPGVVTTKPRVSQ--------------------NGPRAP-------VPAAPPAAPAPEFPGEAENIVES------------------------------------------ERPPAPSPTLSPAQSPPP--TAPGNSPERLSLSP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LRP-EPAPDASPSATTP------------------------------------------------------------------------------------TLTTPSLP----------------AELGSPHSTEVDESLSVSFEQVLP---------------------------------------------------------------------------------AGDAGLSLPLR--LARRSTS---------------PHDVDLCLVSPCEFSHRK------------------------------------------------------------------------------PPPPASPGSS-DSSARSQERP-----PETPPTSVSESLPTLSDSDPVPVAD----------SDDDAGSE-------------SAARDPLPTP-RVPPPLPDAPG----ICMVDPEALPPRARQPLSTANSSRGRKAPARPS------------------------------SASAAPRAA-TVAAKTKGPVGD--RSRPLSARSEPADKPGRVPLTRKPSVPKTVPKMASATRNSSGPSSR--PAPLAAGSPVYLDLAYLPGGGAGHL-DQNFFLRVRALCYVISGQGQRQEEGLRGVLDALLAGKR-------------------------------------------------------------------------QWDLDLQVTLIPTFDSAVMHRWYEETHE-------------------------------QHQALGIRVLGSGSLVSMQDEAFPACKVEF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C052-1", "uniprot_id": "MAP1S_MOUSE", "id": "Q8C052-1", "name": "Microtubule-associated protein 1S", "aln": "-----------------------------------------------------------------------------------------MAAVMAAPEAVEAPSS-----------LLLLVVGGECGCPGLLAYVMEELERGVRSWEDVDPAVCSLDEQLKAFVSRHSATFSSIVKGQRSLHHRGETLETLVLLNPSDKSLCDELRNLLMDPAPHKLLVLAGPCLEETGELLLQTGGFSAHHFLQVLGDKEVQDALASAP---AAPALTVSCPTFGDWALLGPVPG-------LQLRLNPPAQLPAS-EGLRAFLEYVAESLEPPSPFELLEPPAAGGFLRLARPCCYVFPGGLGDAAFFAVNGFTVLVNGGSNPKSSFWKLVRHLDRVDAVLVTHAGADSLPGLNSLLRRKLAEREAAAGPQGQ-HEERLRRLLSPALGVVFLNAREAASRLR------GGEDEAVCARSLLRSLGIAPLPLQRGPQP-SCPTVLFEKLGVGRLELFVLHPPPG-------------------------------DPAAPACALLVWQPAAPGDKVVRVLFPGRTPPARLLDGLQRLQHLPCLRRPVVTTHDLEA------PSRANSQDSLA--------SRDS----------------------ARKEPVRGTVG-------------------------SIANRSTVRREP-------ALATR------------------------------------------------------DQKKDTRSG---PTQPTARDTRRSGPGVVNTKPRVSQ--------------------NGPRAP-------VLAAPLTAPVAECPGEAENILES------------------------------------------ERPPAPSPTLSPAQSPPP--TAPGNSPERLSLSP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LRP-EPAPDASPSATTP------------------------------------------------------------------------------------TLTTPSLP----------------AELGSPHSTEVDESLSVSFEQVLP---------------------------------------------------------------------------------AGDPGLSLPLR--LARRSTS---------------PHDVDLCLVSPCEFSHRK------------------------------------------------------------------------------PPPPASPGSS-DSSARSQERP-----PETPPTSVSESLPTLSDSDPVPVAD----------SDDDAGSE-------------SAARDPPPTP-RVPPPLPDVPG----ICMVDPEALPPRARQPLNTTNPSRSRKAPARPS------------------------------SASATPRAA-TVAAKTKGPAGD--RNRPLSARSEPADRPGRVPLTRKPSVPKTVPKMASATRLSSGPSGR--PAPLAAGSPVYLDLAYLPGGGAGHL-DQNFFLRVRALCYVISGQGQRQEEGLRAVLDALLAGKR-------------------------------------------------------------------------QWDLDLQVTLIPTFDSAVMHRWYEETHA-------------------------------QHQALGIRVLGSGSLVSMQDEAFPACKVEF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66K74-1", "uniprot_id": "MAP1S_HUMAN", "id": "Q66K74-1", "name": "Microtubule-associated protein 1S", "aln": "-----------------------------------------------------------------------------------------MAAVAGS--GAAAAPS-----------SLLLVVGSEFGSPGLLTYVLEELERGIRSWD-VDPGVCNLDEQLKVFVSRHSATFSSIVKGQRSLHHRGDNLETLVLLNPSDKSLYDELRNLLLDPASHKLLVLAGPCLEETGELLLQTGGFSPHHFLQVLKDREIRDILATTPPPVQPPILTITCPTFGDWAQLAPAVPGLQGALRLQLRLNPPAQLPNS-EGLCEFLEYVAESLEPPSPFELLEPPTSGGFLRLGRPCCYIFPGGLGDAAFFAVNGFTVLVNGGSNPKSSFWKLVRHLDRVDAVLVTHPGADSLPGLNSLLRRKLAERSEVAAGGGS-WDDRLRRLISPNLGVVFFNACEAASRLA------RGEDEAELALSLLAQLGITPLPLSRGPVP-AKPTVLFEKMGVGRLDMYVLHPPSAG----------------------------AERTLASVCALLVWHPAGPGEKVVRVLFPGCTPPACLLDGLVRLQHLRFLREPVVTPQDLEG------PGRAESKESVG--------SRDS----------------------SKREGLLATHPRPGQE------------------RPGVARKEPARAEAPRKTEKEAKTPR------------------------------------------------------ELKKDPKPS---VSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPP-----SLRCGEASPPSAACGSPASQLVATPSLE--------------------------LGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LRGGEAGPDASPTVTTP------------------------------------------------------------------------------------TVTTPSLP----------------AEVGSPHSTEVDESLSVSFEQVLPPSAP-----------------------------------------------------------------------------TSEAGLSLPLRGPRARRSAS---------------PHDVDLCLVSPCEFEHRKAV--------------------------------------------------------------------------PMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGA--------ADSDEDTEGF----------GVPRHDPLPDPLKVPPPLPDPSS----ICMVDPEMLPPKTAR--QTENVSRTRKPLARPN------------------------------SRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGS-ASSRPGVS--ATPPKS--PVYLDLAYLPSGSSAHLVDEEFFQRVRALCYVISGQDQRKEEGMRAVLDALLASKQ-------------------------------------------------------------------------HWDRDLQVTLIPTFDSVAMHTWYAETHA-------------------------------RHQALGITVLGSNSMVSMQDDAFPACKVEF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PDQ3-1", "uniprot_id": "A0A8M9PDQ3_DANRE", "id": "A0A8M9PDQ3-1", "name": "", "aln": "-----------------------------------------------------------------------------------------MAAEHIGELASMENSNRGARPGFCSEKYSLLVIVGQPGPAGFVDLLVSEIERGLRSWD-VDSSACNIDEQLKLFISRHSAFFSEDLKGQKTLQHSGDVLETQVIVNPSHDLVCSEVRRLISDTSLHKLLILAGQCVEETGDLVLQTGSFSLEDFIQIFTDEEIGDLLSSADP-TQKARLTLSCPESGKWKTSQLEKHN--LQDYIEIKTNPPLVLPEM-EGLQEFTEYLSESLEPQSPFDLLVPPSTVGFLKLSRPCCYVFPGGRGDSAFFAVNGFNVLVNGGSDARSCFWKLVRHLDRVDSVLLTHAGVDNLPGINSLLYRKVAEHEEEQSAGSQSSEDWQKNLISPEIGVVFFNASERLKKLQSDPRVIRSSDQVSLTLQHLEKLSIFPERLSRSAGPTIEPVILFQKMGVGRLDLYVLNPVKGSKELEAFLQTWPA------SPPNIKPTDIPLESIVSICALLVWHPANPREKIIRVLFPGCTPQSKIFEGLERLKHLEFLKHSVVSLKDLEASKLDKQPKHTGSKESLKSI------SKESRPGSALLKDKVVKVDPKKQDTKTKTKPTNETVPKEGKESEEKAKPKDDVKLRPKTAEKQVAKKEPAKDEKKEVRKKEEKPPTSIAKKDENVEKRKEPLKKD-------------------LGAKPKKDIIKPDLKKEIKKEVKPEDKRTTKPPVKEVKKPAGSLPGNTESRKSVGKNGSLKKDVLVSKKDPVTKGKPKPDKKEPDNVKSSSGDNSKTSTPEDISKQLEKLKLDNEHGSLQDAEGNNMSSRTASDSSAGQVNGSKTGTEESPEKFRSMDGTPGSNNPSPLTKTPKSERSVNFDLTPTE----------------------------------------------------------------------------------------------------------------------------------------------------------------LDGCLKEDACTSSDEKTLELVSPADSGKNSSWQTRYPQSPDNACLDSSEDCKVGIRKSGLAVEDGQLGICKNSRSNIENSSISSQDRQSSFLSS---------------------TSFKDGSTSITSFP----------------AEVGSPHSTEVEDSLSVSFEQVPVCHPQEEMGSLAYTNGHLA-------------------------------------------------------------DRDPKADMSLPLKTSHNSHHAYDDSENHLYGLQGDVLPHDVDLCLVSPCEFKHHKSL--------------------------------------------------------------------------E-NQQGLSSEVAAPSPDLSQEPLRDHQSQETT-SSVSVSLISVSDSDVPPATEECPSISEELDSEEDTTSDLFPPHHPSSHSLHHNSQDPPPAPMKDLPPLPPQRG----ACMADPEAD--------SQGKSSKNVTAKTKKT------------------------------AAAAPTKTG---SANVVAQTGKTKIGGPVSATG-----TIRVTSSLDTRPPSRSAIGGSRPTSSKSSSSS--ASVSLGSAPVCLDLAYLPSGSAAHTVDVEFFRRLRSSCYIISGDEPHKETVMRSILDSLLEGKA-------------------------------------------------------------------------SWP-DVQVTLIPTFDSLSMHNWYQQTHE-------------------------------RQKDLSITVLGSNSTVAMQDETFPACKVEF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W596-1", "uniprot_id": "FUTSC_DROME", "id": "Q9W596-1", "name": "Microtubule-associated protein futsch", "aln": "MGDQPKATTTATGGAAGPVPEGDAVMATTNQDALAKGAGDGPAQDAAQEPGQAEHGEPGDGGDGGDDGATDAGASSLPPSEIGGRAPLDTACSDADGGAPSSLAGGIVGPPSPLTGCYLLIVLGEPHSEEHKDNILQHLLKGFLSWD-VSDCHVDLEEELN-TITQHAPEGEEARHGERLIQYASENLVTEVLIHPQYNTLIQCMRNLLSSFTRHRHIIHAGYTFSGNGSWILQDGTFSVADFSEAFQEHDVQRVIRAYAD---TITMNIHCADAGLWHTLPEKAFAR----QCRIRINPVDVLDTSSECINGFIDYLAPMVMPTSLRELLETSDVVGNIRFTHPTLYVFPGGQGDAALFGINGFNMLVDGGFNRKACFWDFARHLDRLDAVLMTRLNNSNVQGLGAVVSRKRDAHVYPQIGHFFGNVPDRKGLPSPDGDKDRDPLLIDLFERG------------HGIVSDLKALDLKPQCCYRNQEP----VNLYHKVGHGTLDMYVISPARDSKEVKEFLQKWHAGDQRLFAARDSRDFNFPLQNLVSICALLVWQPANPDDTITRILFPGSTPDFKIQEGLEKLKHLEFMKHSTCTAKSIAPAIQTVTSTRKSLKSAIEATPAPPSASYKTTKFSPVASAALAVQHPQQQDNKAKEAAAAAAAAAAAAASAATIARAKADSMDTDAEPEHEADPEPADTGDEAAPTEQEPEAETEPEPEHEPEAEQDKDVGEEKKVEVLIMKPQQATPAVIAASGKDGVDAASADATPTGKLSKASAKGKADKPRAEVKPVVRSRIDTKPPKSMDRKLAKRDEKKSSPTTTPAARAPVAQNAKPKVLSRPATKSSPSSTPAKSAKEANNRKVLESKQQAARVQATSTVSRR-------VTSTASERRVQQQAEAKTAATGATQATQRKPISRRPRGVSPSKRAPAPGSPVKQAKPKAADLKKTRLDKGGTTDSSLVSTPSADEATAAKKLQDLTASQELDAEKQRELDDLKEEQEVVREIEAVFSRDEMKRQQHQQIKAELREMPAEGTGDGENEPDEEEEYLIIEKEEVEQYTEDSIVEQESSMTKEEEIQKHQRDSQESEKKRKKSAEEEIEAAIAKVEAAERKARLEGASARQDESELDVEPEQSKIKAEVQDIIATAKDIAKSRTEEQLAKPAEEELSSPTPEEKLSKKTSDTKDDQIGAPVDVLPVNLQESLPEEKFSATIESGATTAPTLPEDERIPLDQIKEDLVIEEKYVKEETKEAEAIVVATVQTLPEAAPLAIDTILASATKDAPKDANAEALGELPDSGERVLPMKMTFEAQQNLLRDVIKTPDEVADLPVHEEADLGLYEKDSQDAGAKSISHKEESAKEEKETDDEKENKVGEIELGDEPNKVDISHVLLKESVQEVAEKVVVIETTVEKKQEEIVEATTVITQENQEDLMEQVKDKEEHEQKIESGIITEKEAKKSASTPEEKETSDITSDDELPAQLADPTTVPPKSAKDREDTGSIESPPTIEEAIEVEVQAKQEAQKPVPAPEEAIKTEKSPLASKETSRPESATGSVKEDTEQTKSKKSPVPSRPESEAKDKKSPFASGEASRPESVAESVKDEAGKAESRRESIAKTHKDESSLDKAKEQESRRESLAESIKPESGIDEKSALASKEASRPESVTDKSKEPSRRESIAESLKAESTKDEKSAPPSKEASRPGSVVESVKDETEKSKEPSRRESIAESAKPPIEFREVSRPESVIDGIKDESAKPESRRDSPLASKEASRPESVLESVKDEPIKSTEKSRRESVAESFKADSTKDEKSPLTSKDISRPESAVENVMDAVGSAERSQPESVTASRDVSRPESVAESEKDDTDKPESVVESVIPASDVVEIEKGAADKEKGVFVSLEIGKPDSPSEVISRPGPVVESVKPESRRESSTEIVLPCHAEDSKEPSRPESKVECLKDESEVLKGSTRRESVAESDKSSQPFKETSRPESAVGSMKDESMSKEPSRRESVKDGAAQSRETSRPASVAESAKDGADDLKELSRPESTTQSKEAGSIKDEKSPLASEEASRPASVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEETRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESAAEKSPLPSKEASRPASVAESVKDEADKSKEESRRESMAESGKAQSIKGDQSPLKEVSRPESVAESVKDDPVKSKEPSRRESVAGSVTADSARDDQSPLESKGASRPESVVDSVKDEAEKQESRRESKTESVIPPKAKDDKSPKEVLQPVSMTETIREDADQPMKPSQAESRRESIAESIKASSPRDEKSPLASKEASRPGSVAESIKYDLDKPQIIKDDKSTEHSRRESLEDKSAVTSEKSVSRPLSVASDHEAAVAIEDDAKSSISPKDKSRPGFVAETVSSPIEEATMEFSKIEVVEKSSLALSLQGGSGGKLQTDSSPVDVAEGDFSHAVASVSTVTPTLTKPAELAQIGAAKTVSSPLDEALRTPSAPEHISRADSPAECASEEIASQDKSPQVLKESSRPAWVAESKDDAAQLKSSVEDLRSPVASTEISRPASAGETASSPIEEAPKDFAEFEQAEKAVLPLTIELKGNLPTLSSPVDVAHGDFPQTSTPTSSPTVASVQPAELSKVDIEKTASSPIDEAPKSLIGCPAEERPESPAESAKDAAESVEKSKDASRPPSVVESTKADSTKGDISPSPESVLEGPKDDVEKSKESSRPPSVSASITGDSTKDVSRPASVVESVKDEHDKAESRRESIAKVESVIDEAGKSDSKSSSQDSQKDEKSTLASKEASRRESVVESSKDDAEKSESRPESVIASGEPVPRESKSPLDSKDTSRPGSMVESVTAEDEKSEQQSRRESVAESVKADTKKDGKSQEASRPSSVDELLKDDDEKQESRRQSITGSHKAMSTMGDESPMDKADKSKEPSRPESVAESIKHENTKDEESPLGSRRDSVAESIKSDITKGEKSPLPSKEVSRPESVVGSIKDEKAESRRESVAESVKPESSKDATSAPPSKEHSRPESVLGSLKDEGDKTTSRRVSVADSIKDEKSLLVSQEASRPESEAESLKDAAAPSQETSRPESVTESVKDGKSPVASKEASRPASVAENAKDSADESKEQRPESLPQSKAGSIKDEKSPLASKDEAEKSKEESRRESVAEQFPLVSKEVSRPASVAESVKDEAEKSKEESPLMSKEASRPASVAGSVKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESVKDEADKSKEESRRESGAEKSPLASKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRDSVAEKSPLASKEASRPASVAESVQDEAEKSKEESRRESVAEKSPLASKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLASKEASRPTSVAESVKDEAEKSKEESSRDSVAEKSPLASKEASRPASVAESVQDEAEKSKEESRRESVAEKSPLASKEASRPASVAESVKDDAEKSKEESRRESVAEKSPLASKEASRPASVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRESVAEKSSLASKKASRPASVAESVKDEAEKSKEESRRESVAEKSPLASKEASRPASVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEADKSKEESRRESGAEKSPLASMEASRPTSVAESVKDETEKSKEESRRESVTEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRESVAEKSPLASKESSRPASVAESIKDEAEGTKQESRRESMPESGKAESIKGDQSSLASKETSRPDSVVESVKDETEKPEGSAIDKSQVASRPESVAVSAKDEKSPLHSRPESVADKSPDASKEASRSLSVAETASSPIEEGPRSIADLSLPLNLTGEAKGKLPTLSSPIDVAEGDFLEVKAESSPRPAVLSKPAEFSQPDTGHTASTPVDEASPVLEEIEVVEQHTTSGVGATGATAETDLLDLTETKSETVTKQSETTLFETLTSKVESKVEVLESSVKQVEEKVQTSVKQAETTVTDSLEQLTKKSSEQLTEIKSVLDTNFEEVAKIVADVAKVLKSDKDITDIIPDFDERQLEEKLKSTADTEEESDKSTRDEKSLEISVKVEIESEKSSPDQKSGPISIEEKDKIEQSEKAQLRQGILTSSRPESVASQPESVPSPSQSAASHEHKEVELSESHKAEKSSRPESVASQVSEKDMKTSRPASSTSQFSTKEGDEETTESLLHSLTTTETVETKQMEEKSSFESVSTSVTKSTVLSSQSTVQLREESTSESLSSSLKVEDSSRRESLSSLLAEKGGIATNTSLKEDTSASASQLEELLVQSEECSSESIVSEIQTSIAQKSNKEIKDARETKVTSQFTTTTSSATKDDSLKETVAEFLATEKIVSAKEAFSTEATKSADDCLKKTTASAVSSTSASQRALFVGTDESRRESLLSQASESRLTHSDPEDEEPADDVDERSSVKESRSKSIATIMMTSIYKPSEDMEPISKLVEEEHEHVEELAQEVTSTSKTTTLLQSSEQSSTTTSSTSKTGASRVESITLTQMDQQTSQSQGDPADRKTPPTAPVSPGVKAMSSTGSAGSVIGAGAGAVAAGGKCESSAASIVSSSGPMSPKDISGKSSPGALTSESQSIPTPLGRESHTDTPESSPKPTSPFPRVSKDELKSLEMQHHSQEQMLAGAAAAAGAECEGDIPELHELRGLECTTALSGSTDKIITTTITTVTKVISADGKEIVTEQKTVTTTDSSEPDSEKVVVTTTRTTSESERDQLLPKEVALLRGLYRASTPGSEDDEDLLLGSPRSATSYELQHSSSGVSKRSDLDADGDESQDDIPPQYGSEEHSTARSILLPRTADPMATSFYGALPDSFDVVMKPSTEPIPIQGAPSGDSQSSESVESSSQTWAGHKFLDQADKDFQRALEEHVQARGAEVMSSVTAKYSYSPSKAEEMEQIVSGTAERQRFPLSDVQRARVAESGFATVGSVASQQQQQEKGGEVEQAVPTTTAVTASTTATASSTGALPKDRLEEWGKPLGLPSPAPLPVEGGADIRTTPKKERRLVATKTRLNNEKNLRRRSESPNKAGKKPAPVYVDLTYVPHNGNSYYAHVDFFKRVRARYYVFSGTEPSRQVYDALLEAKQTWEDKELEVTIIPTYDTDVLGYWVAENEELLAKHRIDLSPSASRCTINLQDHETSCSAYRLEF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. .. **:: .: ::..: :*. **: *. .::*:*: :::*:. .. :*:: ::: .: * * *:::*. . : . :*.*: . : *: :: ** .. .*. :** * ** .* : : :.:: : : :.: *. * * .:: ** * * : * :*:: : * * :** .. * ::: :* *:**** **:*:*.:***.:**:** : ::.**.:.*****:*:**:*: . ..: *:.::: ** : : * ** . . . * *.: * *. * . *:.*:* * *:::*: * .. ******:** * :.: *:**** ** : :** :*:** ::... : :.: . : :.:: * .: :: : : ... . * :. : :.: . . .. . . . .: * : . * . . . . :* : .. : * * : : .::* * ..*: ::: *: *. .:* . : : *:.**:. * * :. .. .. .:* * ::. .: : .::: : .. : . * * : . . ** : : . :: : *. .: :.. . . . * . .. : .. * . .. . . *: : . * . * . . * . : * : : * :..: * : .. .: ::**: * :. :.. :: . :: . :: : * .*** ", "identical_positions": 149, "similar_positions": 301, "identity": "2.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-400", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14919-1", "uniprot_id": "NC2A_HUMAN", "id": "Q14919-1", "name": "Dr1-associated corepressor", "aln": "MPSKKKKYNARFPPARIKKIMQTDEEIGKVAAAVPVIISRALELFLESLLKKACQVTQSRNAKTMTTSHLKQCIELEQQFDFLKDLVASVPDMQGDGEDNHMDGDKGARRGRKPGSGGRKNGGMGTKSKDKKLSGTDSEQEDESEDTDTDGEE-ETSQPPPQASHPSAHFQ----SPP--TPFLPFASTLPLPPAPPGPSAPDEEDEEDYDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D6N5-1", "uniprot_id": "NC2A_MOUSE", "id": "Q9D6N5-1", "name": "Dr1-associated corepressor", "aln": "MPSKKKKYNARFPPARIKKIMQTDEEIGKVAAAVPVIISRALELFLESLLKKACQVTQSRNAKTMTTSHLKQCIELEQQFDFLKDLVASVPDMQGDGEDNHVDGDKGPRRGRKPGSSGRKNGGTGSKGKDKKLSGTDSEQEDESEDTDTDGEE-ETPQLPPQASHPPAHFQ----SPP--TPFIPFTSPLPLPPAPPGPSAADAEDEEDYDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1R8S0-1", "uniprot_id": "F1R8S0_DANRE", "id": "F1R8S0-1", "name": "Dr1-associated corepressor", "aln": "MPSKKKKYNARFPPARIKKIMQTDEEIGKVAAAVPVIISRALELFLESLLTKACDVTQSRNAKTMTTSHLKQCIELEQQFDFLKDLVATVPDMQGDGEENHTEGEKIPRRGRKPGS-GRKNGGAGAKGKDKKLSGTESEQEDDSEDSETEGEEDEDASRTSTHTQPAPYYHSVGMSSPQVSSVTPPVSVSLLPPAVAPPAAEEEDDDEDYDS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************************************************.***:*********************************:*********:** :*:* .******** ****** *:*.********:*****:***::*:*** * .. .. ::*..::: *.* :.. * .* **** . *:* : :*:*****", "identical_positions": 153, "similar_positions": 35, "identity": "72.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4006", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P36776-1", "uniprot_id": "LONM_HUMAN", "id": "P36776-1", "name": "Lon protease homolog, mitochondrial", "aln": "---------MAASTGYVRLWGAARCWVLRRPMLAAAGGRVPTAAGAWLLRGQRTCDASPPWALWGRGPAIGGQWRGFWEASSRGGGAFSGGEDASEGGAEEGAGGAGGSAGAGEGPVITALTPMTIPDVFPHLPLIAITRNPVFPRFIKIIEVKNKKLVELLRRKVRLAQPYVGVFLKRDDSNESDVVESLDEIYHTGTFAQIHEMQDLGDKLRMIVMGHRRVHISRQLEVEPEEPE-----AENKHKPRRKSKRGKKEAE--DELSARHPAELAMEPTPELPAEVLMVEVENVVHEDFQVTEEVKALTAEIVKTIRDIIALNPLYRESVLQMMQAGQRVVDNPIYLSDMGAALTGAESHELQDVLEETNIPKRLYKALSLLKKEFELSKLQQRLGREVEEKIKQTHRKYLLQEQLKIIKKELGLEKDDKDAIEEKFRERLKELVVPKHVMDVVDEELSKLGLLDNHSSEFNVTRNYLDWLTSIPWGKYSNENLDLARAQAVLEEDHYGMEDVKKRILEFIAVSQLRGSTQGKILCFYGPPGVGKTSIARSIARALNREYFRFSVGGMTDVAEIKGHRRTYVGAMPGKIIQCLKKTKTENPLILIDEVDKIGRGYQGDPSSALLELLDPEQNANFLDHYLDVPVDLSKVLFICTANVTDTIPEPLRDRMEMINVSGYVAQEKLAIAERYLVPQARALCGLDESKAKLSSDVLTLLIKQYCRESGVRNLQKQVEKVLRKSAYKIVSGEAESVEVTPENLQDFVGKPVFTVERMYDVTPPGVVMGLAWTAMGGSTLFVETSLRRPQDKDAK-GDKDGSLEVTGQLGEVMKESARIAYTFARAFLMQHAPANDYLVTSHIHLHVPEGATPKDGPSAGCTIVTALLSLAMGRPVRQNLAMTGEVSLTGKILPVGGIKEKTIAAKRAGVTCIVLPAENKKDFYDLAAFITEGLEVHFVEHYREIFDIAFPDEQAEALAVER", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IH79-1", "uniprot_id": "A0A0R4IH79_DANRE", "id": "A0A0R4IH79-1", "name": "Lon protease homolog, mitochondrial", "aln": "MAAYMRVWRSSSGSGSSAIIRAGINALFPRLTLGSSRSYSIIRSRDCLSAARRSASLTDRWS--GGGSAGSGGLTGGCQTRSVFGNRSSGFSGEDGAESSGTADGDGGDEAPDSPPQMSALTPMLVPEVFPNVPLIAVNRNPVFPRFIKIIEVKNKQLMELLRRKVRLAQPYAGVFLKRDDSNESDVVESLDAVYHTGTFVQIHEMQDLGDKLRMIVMGHRRIRINKALSVEPEEPEPMEAEAEEQKSSRRKQKRSRREPEPLADLMEQTVREADLRVEALPPPSVLMVEVDNVAHEEFQVTEEVKALTAEIVKTIRDIIALNPLYRESVLQMMQAGQRVVDNPIYLSDMGAALTGAESHELQDVLEETNIPKRLYKALSLLKKEYELSKLQQRLGREVEEKIKQTHRKYLLQEQLKIIKKELGLEKEDKDAIEEKFRERLRDRTVPQHIMDVINEELNKLGLLDNHSSEFNVTRNYLDWLTSMPWGTNSEENLELRRAKEVLEEDHYGMDDVKKRILEFIAVSQLRGSTQGKILCFYGPPGVGKTSIARSIARALNREYFRFSVGGMTDVAEIKGHRRTYVGAMPGKIIQCLKKTKTENPLVLIDEVDKIGRGYQGDPSSALLELLDPEQNANFLDHYLDVPVDLSKVLFICTANITDTIPEPLRDRMEMINVSGYVAQEKLAIAEKYLVPQLRTLCGLDEQKVKINPEALNLLIRQYCRESGVRNLQKQVEKVFRKVAFRIVSGEETAVDVTSNNLQDYVGKPLFTVDRMYDVTPPGVVMGLAWTAMGGSTLFIETSLRRPRDPPGKDGPKDGSLEVTGQLGDVMKESAKIAYTFARSFLMKEQPDNEFLVSSHIHLHVPEGATPKDGPSAGCTIVTALLSLATNTALRQNVAMTGELSLTGKILPVGGIKEKTIAAKRAGVTCIILPAENRKDFSDLPEYITEGLEVHFVENYSEIYNLVFSTPK--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.:* : *. :: * *.:: . : * .:*:.. : *: * *.* .* * :: * *. ** .. . . :. *.* **. .... * ::***** :*:***::****:.*****************:*:*************.******************* :******.*********************::*.: *.******* **:::..***.**.::*.* :* : * :. . *..******:**.**:***************************************************************************************:*****************************************:*************:: .**:*:***::***.************************:***. *:***:* **: *********:*******************************************************************************************:*****************************************************:******************************:***** *:******.*.*:..:.*.***:******************:** *::***** :*:**.:****:****:***:*************************:*******:* .* * ************:******:*******:***:. * *::**:******************************* . .:***:*****:***************************:*****:*** **. :***********:* **:::.*. : ", "identical_positions": 725, "similar_positions": 141, "identity": "74.28%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4022", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M5N2-1", "uniprot_id": "A0ABK0M5N2_RAT", "id": "A0ABK0M5N2-1", "name": "", "aln": "MGNSYAGQLKSARFEEALHNSIEASLRCSTAVPRPIFSQLYLDPDQHPFSSADVKPKVEDLDKDLVHRYTQNGSLDFSHNVAMNEMEDDEDEEEMSDSNSPPIPYSQKPAPEGSCTTDGFCQAGKDLRLVSLCTEQIDIPAGFLLVGAKSPNLPEHILVCAVDKRFLPDDHGKNALLGFSGNCIGCGERGFRYFTEFSNHINLKLTTQPKKQKHLKYYLVRTSQGVLSKGPLICWKECRSRQSSALCHSTKPISSVSSSVAPENGTANGYKAG-FTQTEAANGTNGHGGKSSTSS----------STPSH-----------------PGNYSLSPRPTYTPIDQAN---------------------MFISGPPKKRHRGWYPGSPVSQSALVVPVPTVRPLSR-TEPLLSTPVPQTQ-LTGILQPRPVPAGETVIVPENLLSNSGVRPVILIGYGNLPYFYGNVGDIVVSPLLVNCYKIPPLENKDLEQLGLTSTHLLSVENMILLTIQYLVRLGPDQIPLREEFEQIMLKAMQEFSVRERALPMGDPCTPVSPAQLPWLARLAASVSQDLVHVIVTQNSLAEGISETLRLLSEMRHCQR--LPDYAVVICASQIRGNEFCVVVLGQHQSRALAESMLTTSEFLKEISYELITGKVSFLASHFKTTSLGDDLDKLLEKMQQRRGDSVVTPFNGDLNECMSPQEAAAMIPTQNLDIDNETFQIYQAQLTVARRLLSQVCAIADSGSQSLDLGHFSKVDFIIIVPRSEVLVQQTLQRVRQSGVLVDLGLEENGTAHQRAEKYVVRLDNEIQSKFEVFMRRVKQNPYTLFVLVHDNSHVELTSVISGSLSHGEPTHGLADRVINCREVLEAFNLLVLQVSSFPYTLQTQQSRISSSNEVHWIQLDTTEDVGCEK--LYFGLNEYSKSLQWGITSPLLRCDETFEKMVSTLLERYPRLHSMVVRCYLLIQQYSEALMALTTMASLRDHSTPETLSIVDDLITSPGKNKSGRGHMLVIRVPSLQLAMLAKERLQEVRDKLGLQYRFEIILGSPTSELTVATHFVTRLKTWRGNDQEEWIPRTYQDLEGLPCIVILTGKDPLGETFPRSLKYCDLRLIDSSYLTRTALEQEVGLACCYVSKEVVRGPAAALDLSGK--ETERVPTSDNDSEELLIDLERPQSNSSAVTGTSGSIMENGVSSSSTAGKPQQQPLTP-----TTSVRLDEGISTGTAVAG--EILKQECDSLGPPMASST--TSKPSSSSSSSAQALSWSGQP------RGLHTALPPVVILSKAAYSLLGSQKGSKLPSSS-LLPHADVAWVSSLRPGLHKDMSSEEQSLYYRQWTSARQHHADYSNQPDPISGVRTLHPRRLLLTGPPQVGKTGSYLQFLRILFRMLIRLLEVDVYDEEEINTDHTDSSELSQSEGEPWPDIETFSKMTFDVSVHDPKYSLMSPVYSEKLAGVKQEVIKE--YKAEQPRKRETMSMMLTKYAAYNTFHHCEQCHQYMDFTPNSQMSDSTLHAFTFSSSMLGEEVQLYFIIPKSKESHFVFSKQGRHLESMRLPLVSDKNLNAVKSPIFTPSSGRHEHGLLNLFHAMEGISHLHLLVVKEYEMPLYRKYWPNHIMLVLPGMFNNAGVGAARFLIKELSYHNLELERNRLEELGVKRQCVWPFIVVMDDSCVLWNIHSVQEQTSQPTEAG-ISSKNVSLKSVLQHIEATPKIIHYAILGIQKWNSKLTSQNLKAPFSRCHVHDFILLNIDLTQNVQYDFNRYFCEDVDFNLRTNSSGLLICRFNNFSLMKKHVQVGGQRDFIIKPKLMVSENLAPILPLQYVCAPDSEHTLLAAPAQFLLEKFLQHASYKLFPKAIHNFKSPVLAIDCYLNIGQEVAICYVSSRPHSSNVNCEGVFFSGLLLYLCDSFVGADLLKKFKFLKGATLCVICQDRSSLRQTIVRLELEDEWQFRLRDEFQTANSSDDKPLYFLTGRHV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B9EJV3-1", "uniprot_id": "GRB1L_MOUSE", "id": "B9EJV3-1", "name": "GREB1-like protein", "aln": "MGNSYAGQLKSARFEEALHNSIEASLRCSTAVPRPIFSQLYLDPDQHPFSTADVKPKVEDLDKDLVHPYTQNGSVDFSHNVAMNEMEDDEDEEEMSDSNSPPIPYSQKPAPEGSCTTDGFCQAGKDLRLVSLCMEQIDIPAGFLLVGAKSPNLPEHILVCAVDKRFLPDDHGKNALLGFSGNCIGCGERGFRYFTEFSNHINLKLTTQPKKQKHLKYYLVRTSQGVLSKGPLICWKECRSRQSSALCHSTKPISSVSSAVAPENGTANGYKAG-FTVTEAANGTSGHGGKSSSCS----------STPSR-----------------PGNYSLSPRPTFTSVDQAN---------------------MFISGPPKKRHRGWYPGSPVSQSALVVPAPTVRPLSR-TEPLLSTPVPQTP-LTGILQPRPVLAGETVIVPENLLSNSGVRPVILIGYGTLPYFYGNVGDIVVSPLLVNCYKIPQLENKDLEQLGLTSTHLLSVENMILLTIQYLVRLGPDQIPLREEFEQIMLTAMQEFSVRERALPLGAPCAPMSPAQLPWLARLAASVSQDLVHVIVTQNSLAEGISETLRLLSEMKHYQR--LPDYVVAICASKIRGNEFCVVVLGQHQSRALAESMLTTSEFLKEISYELITGKVSFLASHFKTTSLGDDLDKLLEKMQQRRGDSVVTPFNGDLDECVSPQEAAAMIPTQNLDVDNETFQIYQPQLTVARRLLSQVCAIADSGSQSLDLGHFSKVDFIIIVPRSEVLVQQTLQRVRQSGVLVDLGLEESGLAHQRAERYVVRLDNEIQSKFEVFMRRVKQNPYTLFVLVHDNSHVELTSVISGSLSHGEPTHGLADRVINCREVLEAFNLLVLQVSSFPYTLQTQQSRISSSNEVHWIQLDTMEDAGCEK--LYFGLDEYSKSLQWGITSPLLRCDETFEKMVSTLLERYPRLHSMVVRCYLLIQQYSEALMALTTMASLRDHSTPETLSIMDDLITSPGKNKSGKGHMLVIRVPSVQLAMLAKERLQEVRDKLGLQYRFEIILGSPASELTVETHFVTRLKTWRGNDQDEWIPRTYQDLEGLPCIVILTGKDPLGETFPRSLKYCDLRLIDSSYLTRTALEQEVGLACCYVSKEVIRGPAAALDLSAK--EAERVPASENDSEELLIDLERPQSNSSAVTGTSGSIMENGVSSSSTAGKPQQQLLTP-----TSSIRLDEGVSASTAVVG--EILKQECDSLDPPMASST--TSKPSSSSSSSAQALAWSRQP------RGLHTALPPVIILSKAAYSLLGSQKGGRLPSSSSLLPHADVAWVSSLRPGLHKDMSSEEQSLYYRQWTSARQHHADYSNQPDPISGARTLHPRRLLLTGPPQVGKTGSYLQFLRILFRMLIRLLEVDVYNEEEINTDHSDDSELSQSEGEPWPDIETFSKMPFDVSVHDPKYRLMSLVYSEKLAGIKQEVIKE--YKVEEPRQRETMSMMLTQYAAYNTFHHCEQCQQYMAFTPASQMSDSTLHAFTFSSSMLGEEVQLYFIIPKSKESHFVFSKQGRHLESMRLPLVSDKNLNAVKSPIFTPSSGRHEHGLLNLFHAMEGISHLHLLVVKEYEMPLYRKYWPNHIMLVLPGMFNNAGVGAARFLIKELSYHNLELERNRLEELGVKRQCVWPFIVVMDDSCVLWNIHSVQEQTSQPTEAG-ISSKNVSLKSVLQHIEATPKIIHYAILGIQKWNSKLTSQSLKAPFSRCHVHDFILLNIDLTQNVQYDFNRYFCEDVDFNLRTNSSGLLICRFNNFSLMKKHVQVGGQRDFIIKPKLMVSENVVPILPLQYVCAPDSEHTLLAAPAQFLLEKFLQHASYKLFPKAIHNFKSPVLAIDCYLNIGQEVAICYVSSRPHSSNVNCEGVFFSGLLLYLCDSFVGADLLKKFKFLKGATLCVICQDRSSLRQTIVRLELEDEWQFRLRDEFQTANSSDDKPLYFLTGRHV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C091-1", "uniprot_id": "GRB1L_HUMAN", "id": "Q9C091-1", "name": "GREB1-like protein", "aln": "MGNSYAGQLKSARFEEALHNSIEASLRCSSVVPRPIFSQLYLDPDQHPFSSADVKPKVEDLDKDLVNRYTQNGSLDFSNNLTVNEMEDDEDDEEMSDSNSPPIPYSQKPAPEGSCTTDGFCQAGKDLRLVSLCMEQIDIPAGFLLVGAKSPNLPEHILVCAVDKRFLPDDHGKNALLGFSGNCIGCGERGFRYFTEFSNHINLKLTTQPKKQKHLKYYLVRSSQGVLSKGPLICWKECRSRQSSASCHSIKPSSSVSSTVTPENGTTNGYKSG-FTQTDAANGNSSHGGKGSASS----------STPAH-----------------TGNYSLSPRPSYASGDQAT---------------------MFISGPPKKRHRGWYPGSPLPQPGLVVPVPTVRPLSR-TEPLLSAPVPQTP-LTGILQPRPIPAGETVIVPENLLSNSGVRPVILIGYGTLPYFYGNVGDIVVSPLLVNCYKIPQLENKDLEKLGLTGSQFLSVENMILLTIQYLVRLGPDQVPLREEFEQIMLKAMQEFTLRERALQIGAQCVPVSPGQLPWLARLIASVSQDLVHVVVTQNSLAEGISETLRTLSEMRHYQR--LPDYVVVICASKIRGNEFCVVVLGQHQSRALAESMLTTSEFLKEISYELITGKVSFLASHFKTTSLGDDLDKLLEKMQQRRGDSVVTPFDGDLNECVSPQEAAAMIPTQNLDLDNETFHIYQPQLTVARKLLSQVCAIADSGSQSLDLGHFSKVDFIIIVPRSEVLVQQTLQRIRQSGVLVDLGLEENGTAHQRAEKYVVRLDNEIQTKFEVFMRRVKQNPYTLFVLVHDNSHVELTSVISGSLSHSEPSHGLADRVINCREVLEAFNLLVLQVSSFPYTLQTQQSRISSSNEVHWIQLDTGEDVGCEEK-LYFGLSEYSKSLQWGITSPLLRCDETFEKMVNTLLERYPRLHSMVVRCYLLIQQYSEALMALTTMASLRDHSTPETLSIMDDLISSPGKNKSGRGHMLIIRVPSVQLAMLAKERLQEVRDKLGLQYRFEIILGNPATELSVATHFVARLKSWRGNEPEEWIPRTYQDLDGLPCIVILTGKDPLGETFPRSLKYCDLRLIDSSYLTRTALEQEVGLACCYVSKEVIRGPTVALDLSGK--EQERAAVSENDSDELLIDLERPQSNSSAVTGTSGSIMENGVSSSSTADKSQKQSLTPSFQSPATSLGLDEGVSASSAGAGAGETLKQECDSLGPQMASST--TSKPSSSSSG-PRTLPWPGQPIRGC--RGPQAALPPVVILSKAAYSLLGSQKSGKLPSSSSLLPHADVAWVSSLRPLLNKDMSSEEQSLYYRQWTLARQHHADYSNQLDPASGTRNFHPRRLLLTGPPQVGKTGSYLQFLRILFRMLIRLLEVDVYDEEEINTDHNESSEVSQSEGEPWPDIESFSKMPFDVSVHDPKYSLMSLVYTEKLAGVKQEVIKE--SKVEEPRKRETVSIMLTKYAAYNTFHHCEQCRQYMDFTSASQMSDSTLHAFTFSSSMLGEEVQLYFIIPKSKESHFVFSKQGKHLESMRLPLVSDKNLNAVKSPIFTPSSGRHEHGLLNLFHAMEGISHLHLLVVKEYEMPLYRKYWPNHIMLVLPGMFNNAGVGAARFLIKELSYHNLELERNRLEELGIKRQCVWPFIVMMDDSCVLWNIHSVQEPSSQPMEVG-VSSKNVSLKTVLQHIEATPKIVHYAILGIQKWSSKLTSQSLKAPFSRCHVHDFILLNTDLTQNVQYDFNRYFCEDADFNLRTNSSGLLICRFNNFSLMKKHVQVGGQRDFIIKPKIMVSESLAPILPLQYICAPDSEHTLLAAPAQFLLEKFLQHASYKLFPKAIHNFRSPVLAIDCYLNIGPEVAICYISSRPHSSNVNCEGVFFSGLLLYLCDSFVGAD-LKKFKFLKGATLCVICQDRSSLRQTIVRLELEDEWQFRLRDEFQTANSSDDKPLYFLTGRHV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8JKP6-1", "uniprot_id": "GRB1L_DANRE", "id": "B8JKP6-1", "name": "GREB1-like protein", "aln": "MGNSYAGQLKSARFEEALHNSIEASLRSSGGDPQPVFTQLYLEPDQYSGHVEDIKP---KMDLSLRSDPSTHVLVKCHSSNSVEDMDDEDD----SDTSSPPLPYLQGPPPDGCCTVDGFCQAGKDLRLVSMATESIEVPAGFELVGAKSPSIPEHILVCAVDKRFLPDENGKNALLGFSGNCVGCGEKGFRYFTEFSNHINLKLSTQPKKQKHLKYYLVKNSQGALCKGALICWKDCKTRPFSNSASSSKP-SSSSSLSSKENGDTNGHSPSPFPLSDSPPARMQSGSSSGIFGPQELGFLKPLNTPTHGTKTLPIVPTALRVNGLTNGLSMDGRSTLLSPPRTNPLSTPSHGYRTTETGDSPASTAMSTGPPKKRHRSWHPTTLVPIPATAVPVPAIRPLTCSSGPLLSLSNQQPASVSGVIQPQPITAGETVIIPDNLLNSYGVRPVLLIGQGTLPYFFGNVGDLVVSPLLVSCYKGRELNEKTLASLGMSANQLLTTETMILLTLQYLARLGTEQIPLREEFEQIMLKAM----------LCGPTGPPVSPAQLPWLARMEASVSGGSVQVLVTHGSLGEGISESLRSLSETSPQQQQCLPNYVLIICTSKSGANEFCVLVLGKYQSRALAESMLSTNEFLKEISYELITGKVSVLASHFQSTSLGDNMDKQLVRYQRKRKDRVVQPFQGHLTEYIHSQEAATMIPESGPDLLSDDFQIHPPQLSVARSLLSQVCAIADSGSQSLDLGRFCKVDFLILVPPSHVLVHQTVQRIRQSGVLIDLGIEDVSLAMQKSDKYVVRLDTEVHTKMEAFMRKVKQNPYTLFVLIHDNSHVDLTSALSGSVCHG-ELQGLADRVVNCPEVLEAINLLVLQVSCFPFTLQSRQSRISTQNEVHWPDTENQQGEASPKDLIYFGLKDYSKSLQWGVASPILRCDDAFERMVKTLLERHPHLHSMVIRSYLLIQQYTEALMALTAAPSLRDHVTPQTLAMVEDLLSVPGRSKHGCGHMLLVRVPSLQLARLAQERLEEARDKLGLQYRFAVLLGSPAAEISLPVHFCARLRAWRGCKNEEWVPHTYEDLEGLPCIVILTGKDPLGETFPRSLKYCDLRLIDSSYLTRTALEQEVGLACSYVTRRVIPKTKTATSREERPREGERSSGETAEHDDLPMELERPPSNASAATRTSGSTTENGVSSSSILDKPSSQ---------SDPCGSRTMMDSCSSPVR----FKQECDSQAPSSSSTSSFSSASSSSSSSSSPAAQRPSQSTQAPRECNRTQVFPRTAVLSRAAYTLLAPETLG-HPSSASLLPHADVSWSSPLRPPVPHGLGGAEQSLYYRQWTTARQHHADYEG---PVP---HPHPRRLLLSGPPQVGKTGAYLQFLRILFRMLIRLLEVDVYDEEELEEDVQDKSKVPPSSGPQWPDVEDVRKLRFDLCPHDCKFKYSSPVYANRMPKTQSGVKTERLDTEADPPKRNTVSVRLSLFAAHNAFHHCEQCHHYSEPIPAAQLSDCTFHAFTFCSSMLGEEVQLHFIIPKSKESHFVFSQQGSHLESMRLPLLSDKESGMMKSPIFTPTTGRQEHGLLNIYHAMEGAEHLHILVVKQYEMPLYRKYWPNHILLVLPAMFNNSGVGAARFMIKELSYHNLELERNRQEEQGVKRQDVWPFIVMMDDSCVLWNAQ-------QPGPDGKTEVMNVSLKSVLQHMEATPKISQYAVCGLRKWSSSLSSQAPTSPFSRCHLHDLILLNVDLTQNVQYDLNRFTCEEVDFNLRANSSGLLLCRFNQFSIMKKHIPIGGHKDFLIKPKLMRIETPVRVCASQYVCAPDSEQTLLAAPAQFLLEKFLQSCSHRLFPLALSNSANPVLSIDSYLNLGPEVQVCYVSSRPHSVNVDHQGVIFSGLLLYLCDSFVVSSLLKKFNFLKGATLCVICQDRSSLRQTIVRLELEDEWQFRLRDEFQTANCSEDRPLYFLTGRHI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************************.* *:*:*:****:***:. *:** .:* .* : : :. . ::::*:*::* **:.***:** * *.*:*.**.**************:. *.*::**** *******.:****************::************:****:****************:**************:.***.*.**.*****:*::* * . * ** ** ** : *** :**:... *. :::. . *.... . .**:: ... *:. *.: . ::. : :********.*:* : :. .. .**.*::***: : **** . *. ::*::**:*: ******:*:***.. *****:*** *.****:*****:*******.*** *::* * .**::..::*:.*.*****:***.***.:*:***********.** * *:**.*******: **** . *:*:**:.**.*****:** *** *: **:*.: **:*: .*****:***::**********:*.****************.*****::*****::** * : *::* * ** **:*.* * : .****:*** .. *: .: *:*: .**:*** *******************:*.****:*:** *.***:**:**:******:***:*: . * *::::******.*:::*:*.***:***********:******:***.:***:.*. :******:** *****:********.**:***::*****:.***** : :. :. .. : :****.:********::**:****::**:**.*****:*:*****:*.*******:*******: .***** **:**::::**:: **:.* * ****::****:*** **:***:*.********** ::**.*::*::: .** :**::*** . :**:*:**:**:************************************************.**::.*: . .* . . : * ** . . : ::* ::**** **:**.* **** ******** .*...* : . :.: :: . :****** * :*:: :* .*****. . : . *. . .:* . :**:***:**..:. . ***: *******:* *.*** : :.:.. ********** ********.. * . *******:*********:*********************:***:: * :.*::. *.* ***:* . *: **:. ** *: * **::::. :. * .* . :* :*:*:*: *: :**:*:*******::* . :*:**.*:*****.**********:**************:** *********:***: . :*******::**:******::***** .***:****:**************:****.****:*******:*************** ** *:*** ******:********* : ** * . *****:****:****** :**: *::**.*.*:** .:******:**:**** *********:**: **:.*****:******:****:**:****: :**::**:****:* *. . : . **:******:**************** .*::*** *: * .***:**.***:* ** :**:****** **: :**:************* :. ****:******************************************.*:*:*********:", "identical_positions": 1169, "similar_positions": 457, "identity": "58.8%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4025", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4VBD2-1", "uniprot_id": "TAPT1_MOUSE", "id": "Q4VBD2-1", "name": "Transmembrane anterior posterior transformation protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGVCDAAAPGEGGGGGADGPERTGRGEAEQPGG-GGHG--PAPQHTETL----GFYE-SDRRREKRRGRAELSLLRFLSAELTRGYFLEHNEAKYTERRERVYTCMRIPRELEKLMFFGIFLCLDAFLYVFTLLPLRVFLALFRLLTLPCYGLR-----DRRLLQPAQVCDILKG-------VILVICYFMMHYVDYSMMYHLIRGQSVIKLYIIYNMLEVADRLFSSFGQDILDALYWTATEPKERKRAHIGVIPHFFMAVLYVFLHAILIMVQATTLNVAFNSHNKSLLTIMMSNNFVEIKGSVFKKFEKNNLFQMSNSDIKERFTNYVLLLIVCLRNMEQFS----------WNPD-----HLWVLFPDVCMVIASEIAVDIVKHAFITKFNDITADVYSEYRASLAFDLVSSRQKNAYTDYSDSVARRMGFIPLPLAVLLIRVVTSSIKVQGILSYACVILFYFGLISLKILNSIVLLGKSCQYVKEAKMEEKLFNPPPASTP---GKPSSKSQ--SKGKPSQGLSTEENLSASVTSQPGHQKENVIP------------------------------------------LLVTSNSDQFLTTPD-GDEKDITQENSELKHRSSKKDLLEIDR----FTICGNRID----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A632-1", "uniprot_id": "A0A8I6A632_RAT", "id": "A0A8I6A632-1", "name": "", "aln": "MIINMQERCSQGSRATGSAPAGATELEPGPSRRAAKARRVAPAHSGHRTGTRGSGRTESHAEPRRRPPSPTARPGDMEPGAAPRSAEPAARHGDGRKKMAAAVAAATAASHAPLTPMARAGRRTTDGGCPGSGEGRGEAARGPAGGGGRAGGWREVAGTVCGFRNMAGVCDAAAPGEGGGGGADGPERTGRGEAEQPGG-GGHG--PAPQHTETL----GFYE-SDRRREKRRGRAELSLLRFLSAELTRGYFLEHNEAKYTERRERVYTCMRIPRELEKLMFFGIFLCLDAFLYVFTLLPLRVFLALFRLLTLPCYGLR-----DRRLLQPAQVCDILKG-------VILVICYFMMHYVDYSMMYHLIRGQSVIKLYIIYNMLEVADRLFSSFGQDILDALYWTATEPKERKRAHIGVIPHFFMAVLYVFLHAILIMVQATTLNVAFNSHNKSLLTIMMSNNFVEIKGSVFKKFEKNNLFQMSNSDIKERFTNYVLLLIVCLRNMEQFS----------WNPD-----HLWVLFPDVCMVIASEIAVDIVKHAFITKFNDITADVYSEYRASLAFDLVSSRQKNAYTDYSDSVARRMGFIPLPLAVLLIRVVTSSIKVQGILSYACVILFYFGLISLKILNSIVLLGKSCQYVKEAKMEEKLFNPPPASTP---AKPSNKSQ--SKCKSSQGLSTEENLSASITSQPVHQKENVIP------------------------------------------LLVTSNSDQFLTTPD-GDEKDITQENSELKHRSSKKDLLEIDR----FTICGNRID----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NXT6-1", "uniprot_id": "TAPT1_HUMAN", "id": "Q6NXT6-1", "name": "Transmembrane anterior posterior transformation protein 1 homolog", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGVGDAAAPGEGGGGGVDGPQRDGRGEAEQPGGSGGQGPPPAPQLTETL----GFYE-SDRRRERRRGRTELSLLRFLSAELTRGYFLEHNEAKYTERRERVYTCLRIPRELEKLMVFGIFLCLDAFLYVFTLLPLRVFLALFRLLTLPCYGLR-----DRRLLQPAQVCDILKG-------VILVICYFMMHYVDYSMMYHLIRGQSVIKLYIIYNMLEVADRLFSSFGQDILDALYWTATEPKERKRAHIGVIPHFFMAVLYVFLHAILIMVQATTLNVAFNSHNKSLLTIMMSNNFVEIKGSVFKKFEKNNLFQMSNSDIKERFTNYVLLLIVCLRNMEQFS----------WNPD-----HLWVLFPDVCMVIASEIAVDIVKHAFITKFNDITADVYSEYRASLAFDLVSSRQKNAYTDYSDSVARRMGFIPLPLAVLLIRVVTSSIKVQGILSYACVILFYFGLISLKVLNSIVLLGKSCQYVKEAKMEEKLSNPPATCTP---GKPSSKSQ--NKCKPSQGLSTEENLSASITKQPIHQKENIIP------------------------------------------LLVTSNSDQFLTTPD-GDEKDITQDNSELKHRSSKKDLLEIDR----FTICGNRID----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BIE7-1", "uniprot_id": "TAPT1_DANRE", "id": "A2BIE7-1", "name": "Transmembrane anterior posterior transformation protein 1 homolog", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADSVAAGLGDENETENEDKE-REKRLFSGVKKMEKQAAASDVTETL----GFYERKAKCKDRKTNVSDLSLVRFISAELTRGYFLEHNEAKYTERRERVYTCLRIPKELEKLMIFGYFLCLDVFLYVFTLLPLRVLLALVRLLTLPCCGLS-----GSRILQPAQVCDVLKG-------FIMVLCYFMMHYVDYSMMYHLIRGQSVIKLYIIYNMLEVADRLFSSFGQDILDALYWTATEPKERKRAHIGVIPHFFMAVLYVFLHAILIMVQATTLNVAFNSHNKSLLTIMMSNNFVEIKGSVFKKFEKNNLFQMSNSDIKERFTNYTLLLIVCLRNMEQFS----------WNPD-----HLWVLFPDVCMVIASEIAVDVVKHAFITKFNDITADVYSEYRASLAFDLVSSRQKNAYTDYSDSVSRRMGFIPLPLALLLIRVVTSSVKIQGSLSIVCVLLFYLGMITLKVLNSIVLLGKSCMYVKEANMEEKLFQNPPSAAP---SRVSSRAHRTKHTREPPGDPAEEGMSASVTTQPTQQDECPAP------------------------------------------QIPTSESDQFLTTPDESEEKSLIQDDSELKHRAPKKDLLEIDR----FTICGNRID----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VED0-1", "uniprot_id": "TAPT1_DROME", "id": "Q9VED0-1", "name": "Protein TAPT1 homolog", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------MNATLNSAGGKRQLRFRGDVTGSRVEELHHQQQEEQKQKAPLAQDDVAATPTATPAA----GSAQ--QRLQSGTAETCTNTFYDFFKVEMTRGYMLEHDEERYSARRQKIYSFMRIPRDLERFMVYGIMQCADSFLYIHTFLPVRFVMAVWALVSRTVARIFRLRSSGQRLLSPAEICDLLKG-------VIWMTVTLIMLLVDTNRVYHIIKSQSIIKLYIFYNMLEVGDRLLSAFGQDTIDALFWTATEPKNSKREHFGVLTHVLFTLIYVFLHSGLIMFQATCLNVAVNSNNKGLLTIMISNNFVELKGSVFKKFDKNNLFQLTCSDVRERFHLSVLLFIVVIQTMKEFD----------WSIT-----QFCVMLPDCFAVLFTEILIDWVKHAFITRFNELPESIYREYTTSLAYDMTQTRQKHAFSDHSDLVARRMGFIPFPLAVVLIKAIYTAVSFENLAAWLLFLLAYLFAMGLRICLTICALGKACKLMKEHQTERNSSTPSSMTNVPVIGAAAPVSAAATGGQNHNNNNNNNNNSISIGSKPAQVTTLLTPPSAGHLDVSKNFSRTSIASTSTPKKAVSEQELDVTNSLELGATALFSNSDVDLDDVCLNEQVTNTNTSSAVQEVYQEQDLVRSQPDLMLLNNSGDGVTSAKAKKATQRLPKRTHKRSESEPGMPSMVEKGGAAGIAGGNQTTQL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40085-1", "uniprot_id": "TAPT1_YEAST", "id": "P40085-1", "name": "Endoplasmic reticulum membrane protein 65", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQHKDTAVAKDTAKKRLLRRNSAPSAIHIISRLD---------KKWSFLWNTIDRHNIVEEQDESSAAKSEEEHEDDYELEQLLNMIRIPMFLEKFMLFALLTSLDCFLYYFTVLPIRLIKGYVKQFKSYRQHYRLQQRSGHKNKIPFRYRITSREYKERCMIFIIVISSILLSKLDTSKLYHRIKRQSTMKLYMLFSVLEMADKMLASLGQSLLTVMLS----RKNSERILLHKCLLVSMSLTYVTIHGYVLVYQAISLNIAVNSYSNALLTLLLSMQFAEIKSSVLKKFDKEGFFQITIADVVERFKLTLLLSITGLRNLQSWSSSLSNTSINFWSPRSTLSIVINILCGPMVSVVGSEVLVDWAKHAYITKFNRIRPQIYDKFYYIIYKDYSTRTHK---------LEDRLG-LPLPAFVVLFIVMVRPTLFKSSEPSYLPSLFRILFMGASVFLLALLAKFTLDLILIKWSKRIEQRFRDQAFNTVVTEEEYVPGLLSGGMGKVDVSTRIALHSDYNKENRIETESVSP---------------------------------------------MRKRKTTLTAECTPPSLNDIRRQKDSKN---PRSLENVAR----YKMVSKRIW----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . .:. :. :.. : . ..:* . . ::: . :*** **::*.:. : . * *** .*.**:*.. . .. . : * . : .* : ::: :* . :** *: ** :***:::.:**:.*::::::**. : .: *: :* : . ::: ** :*. ::: ** **:*.** .:.***:::* :*.*:*.**:***:*:.:**:: :*: *** ** *. ::.::.:. *. : :: *: :*: :* .***:**:** : .:* :: : * :* : *:* :*:* ::*: .: . .:. . * : : : : : :. . . . . . .: * : . * . . .. :. :.* . . .. : ", "identical_positions": 88, "similar_positions": 172, "identity": "10.21%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4027", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UKT4-1", "uniprot_id": "FBX5_HUMAN", "id": "Q9UKT4-1", "name": "F-box only protein 5", "aln": "---MSRRPCSCALRPPRCSCSASPSAVTAAGRPRPSDSCKEESSTLSVKMKCDFNCNHVHSGLKLVKPDDIGRLVSYTPAYLEGSCKDCIKDYERLSCIGSPIVSPRIVQLETESKRLHNKENQHVQQTLNSTNEIEALETSR-LYEDSGYSSFSLQSGLSEHEEGSLLEENFGDSLQSCLLQIQSPDQYPNKNLLPVLHFEKVVCSTLKKNAKRNPKVDREMLKEIIARGNFRLQNIIGRKMGLECVDILSELFRRGLRHVLATILAQLSDMDLINVSKVSTTWKKILEDDKGAFQLYSKAIQRVTENNNKFSPHASTREYVMFRTPLASVQKSAAQTSLKKDAQTKLSNQGDQKGSTYSRHNEFSEVAKTLKKNESLKACIRCNSPAKYDCYLQRATCKREGCGFDYCTKCLCNYHTTKDCSD------GKLLKASCKIGPLPGTKKS------KKNLRRL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TSG3-1", "uniprot_id": "FBX5_MOUSE", "id": "Q7TSG3-1", "name": "F-box only protein 5", "aln": "---MSRRTCSDLRRPSSCPCRLG-ARTTVDG-------CKEESPVLSVTMKC-FNCNPDLSELEVVKPEDSGIEASYSPVCLEPSCNDCVRNHERLSFIDSPIVG------------HDNKENQRVQNTLDSSNETEELEASR-LYEDSGYSSFTQ----SDRDDGILILENFRNSPQARLLPSQSPDQHPNKTLLPVLHFERVVCSTLKKNGKRNPKVDREMLKEVIASGNFRLQNIIGKKMGLEHLDILAELSRRGFVHLLANILTKLSGMDLVNLSKVSRIWKKILENNKGAFQLYSKTMQRVIESS-KLSLHATTRGYVVGRAALTCVQKSSTWAPPKKDVQIKSSSQRGQRVSTYSRHNEFVEVAKTLKNNESLKACVRCNFPAKYDHYLERAVCKRESCQFEYCTKCLCAYHNNKDCLN------GKILKASCKVGPLPGTKKS------KKNLQRL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q0V967-1", "uniprot_id": "FBX5_DANRE", "id": "Q0V967-1", "name": "F-box only protein 5", "aln": "---------------MKCPN------------------YTEDSTVLCHMEKTETDLGEVKG--HKVSPRKTGALSLRSPAATNVSTPLESRSKG----------------------PHNKENYQNKRHSLDMASDDEVIFSGSGLTEDSGYLSLHN------SQVDVDGLDSLERSEENCVSSQSLDVECHSGPCLPVLNFQEEACRELQRSYKKNRSYDWTVVDKVAEN--FGLHNVIGGKMGRQFVDILCKLMRKDMRHILARILGLLGDCDLISCTKVSRTWRKIICQDQLALQRWKKAEKTRRDSG--RSMGSLSRDFTLDRVVFSCMQTVSSPPAHKAVKKPPCHMGGAQNATKSSRFQQYVEAAQSLKQHESLRRCSRCSSPARFDAVMQRAVCTRISCAFEFCTLCQSAFHDSTPCRN------TVRSFSSTQKTLVAGSARS------KRSIRRL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VM76-1", "uniprot_id": "Q9VM76_DROME", "id": "Q9VM76-1", "name": "", "aln": "MSAYYRRAALRKKSPSRGSS----------------FELEMNESGYTSFLALHNSTAETPFLLEDAEGENCRNASNTTTFFRGLNTPSGHQEQD----------------------LYWGKPYPRTQPQKKFSAEEEPFSMTPRLQDEHSLPKRRK----KHFQSPHSSPKKSKKLLFPHIEEPPKNRFYGGVEKLDIVAKLAQWQPALQCILRHVGAHTLDVMTKVSPAWKQAVYRSQRDLERLQNHRLKLNLTKENP-HVPKRCSHVPKANHTVPLQTSN---HSSLANSAASLMDSGNSSIHLMDVDAGRVLREQTQRVKCPRCGRGSRVFISEAAKCGENLLSQTLPIG-RTTSTFP-----CMTGPPLKRFLSLDLDEVRTSPQ--GPPYNFAECTSVICQFRFCVNCLCKSHPGERCLVTELDTPSKLMMPRERLTPPQRAQNRDPKITRKNSLKRLCF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.. . . .. . :. . :. : . : . : : * : * :: . . : .. : . * :: *: :: :: :: : . : : :* :.. *: . : . . :. : :. :: :: : . :: * . : . : :. . .. .**. ** . * . : * *. * * :*. * . * * . : : . *..::** ", "identical_positions": 23, "similar_positions": 91, "identity": "4.95%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4041", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHG1-1", "uniprot_id": "PIGP_MOUSE", "id": "Q9JHG1-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit P", "aln": "------------------------------------------------------------------------------------------------------MVENSPSPLPERAIYGFVLFLSSQFGFILYLVWAFVPESWLNSLGLTYWPQKYWAVALPVYLLITVVIGYV-LLFGINMMSTSPLDSIHTITDNYAKNQQ-------RKNYQEDAIPALRDVPISEVNKMFFLGAKELNT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LBB8-1", "uniprot_id": "A0ABK0LBB8_RAT", "id": "A0ABK0LBB8-1", "name": "", "aln": "MAAIKHPAITSVSHRLVTGISTYCGNNLQTEGCLETTSFWKRHRAGVPAHPRLHFGPLRPPRLSPPHYGMAAQALMTSPALLSSSPCAGVGQGCRLSKATGKMVENSPSPLPERAIYGFVLFLSSQFGFILYLVWAFVPESWLNSLGLTYWPQKYWAVALPVYLLITVVIGYV-LLFGINMMSTSPLDSIHTITDNYAKNQQ-------RKSYQEDAIPALRDIPISEVNRMFFLDAKELNT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57054-1", "uniprot_id": "PIGP_HUMAN", "id": "P57054-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit P", "aln": "---------------------------------------------------------------------MVPR---------STSLTLIVFLFHRLSKAPGKMVENSPSPLPERAIYGFVLFLSSQFGFILYLVWAFIPESWLNSLGLTYWPQKYWAVALPVYLLIAIVIGYV-LLFGINMMSTSPLDSIHTITDNYAKNQQ-------QKKYQEEAIPALRDISISEVNQMFFLAAKELYTKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q1D2-1", "uniprot_id": "A0A2R8Q1D2_DANRE", "id": "A0A2R8Q1D2-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit P", "aln": "----------------------------------------------------------------------------------------------------MVMVENSPSPLPERAIYGFVLFLGAQLGFLLYVVWAFVPDSWLHAAGLTYWPQKYWALAGPIYLLVALSTCFV-LLFGVNMMNTAPLASVDNITDAYGRSQR-------VDEDQPGAIPRLRDVSVSEMSRLFYL---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04082-1", "uniprot_id": "GPI19_YEAST", "id": "Q04082-1", "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI19", "aln": "------------------------------------------------------------------------------------------------------MYTKEYYWFSQYMIITSTLVLTIIWSILPSSLGEAAPKQFINTL-LDIFPQRRWIITLESIMLMGMLCTYIGLLMYNEDTLTPPLDSLSTVTDAGGQLVIEDDPDVFVKKWAFKETSGIYDLSLMDACQLLYLYDNDHTST-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. :.: * .*.* .:: : *..:::: * :**: * :: :*: : :: **: : *.** *: .:** .: .. . : *:.: : ::::* ", "identical_positions": 20, "similar_positions": 46, "identity": "8.2%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4042", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P27797-1", "uniprot_id": "CALR_HUMAN", "id": "P27797-1", "name": "Calreticulin", "aln": "-MLLSVPLLLGLLGLAVAEPAVYFKEQFLDGDGWTSRWIESKHKSDFGKFVLSSGKFYGDEEKDKGLQTSQDARFYALSASFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNSLDQTDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDPSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P14211-1", "uniprot_id": "CALR_MOUSE", "id": "P14211-1", "name": "Calreticulin", "aln": "-MLLSVPLLLGLLGLAAADPAIYFKEQFLDGDAWTNRWVESKHKSDFGKFVLSSGKFYGDLEKDKGLQTSQDARFYALSAKFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPSGLDQKDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDAAKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDANIYAYDSFAVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDDDRDEDEDEEDEKEEDEEE-SPGQAKDEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1Q8W8-1", "uniprot_id": "F1Q8W8_DANRE", "id": "F1Q8W8-1", "name": "Calreticulin", "aln": "MTALSLLFMAVSVALITAESNVYFREQFEDGDSWRSRWVESKHKTDYGKFVLSAGKFYGDAEKDKGLQTSQDAHFYAMSARFGDFNNKDQPLVIQFSVKHEQNIDCGGGYIKLFPSDLNQEDMHGDSTYNIMFGPDICGPGTKKVHVIFNYKGKNHLINKDIRCKDDEYSHLYTLIVNPDNTYEVKIDNKKVESGSLEEDWDFLPSKKIKDPEAKKPEDWDEREKIDDPEDQKPEEWDKPENIPDPDAKKPDDWDEEMDGEWEPPMVTNPDYKGEWKPRQIDNPAYKGKWVHPEIDNPEYTADSEIYKYDSIGVIGLDLWQVKSGTIFDNFLITNDPKLAEEVGTETWGATKDAEKKMKESQEEEDRKKHDEEEKSRKEEAKEEEEEEKEEEDEEEEEEEE-EEDEEEETDSKLKDEL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: :: :.* .*:. :**:*** ***.* .**:*****:*:******:****** ************:***:** * *.**.*.**:**:*************:****..*:* ****** *************************** ************::*******.***********.:*******:******.******:* ******** ***** *.***:*****:*********:*************:: **:************* ***.*:*********:.*..** **.:.*:********************* ***.*.****.** ***:**:.*:**:* *.:**:*.**** : *::*:.::.**:*::*:: ****** .: ****", "identical_positions": 303, "similar_positions": 79, "identity": "72.49%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4044", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZSR7-1", "uniprot_id": "D3ZSR7_RAT", "id": "D3ZSR7-1", "name": "Coiled-coil domain-containing protein 102A", "aln": "MSHGPSPRLAESPQLSKSSLLTILGSPSPERMGPADSLPPTPPSGTPSPGPPPTLPLT-APALLADGDWESREELRLRELEEARARALQMEKTMRWWSDCTANWREKWSKVRAERNRAREEVRQLRQRLDTLTKELAGARRERQEAQGECEARGRELARLR-------GARGAADKTQEGPEAER--------------------------------EHEPVRDIGAERSPGSQ-ELDLVESLLKSRPEELEGCWDAC---SVAAGGSRVSSGRQDRNRLPWEDTAGTEED--TSKLTALRLRLDESQKVLLKEREDKLALSKNIEKLEGELSQWKIKYEELSKTKQEMLKQLSILKETHQDELGRMSEDLEDELGARSSMDRKMAELRGEMERLQAENAAEWGRRERLETEKLGLERENKKLRAQVGDLEEALARRRRQNASALDCDLRASQAALFEKNKELADLKHVHSKLKKQFQEKVAELAHANRRVEQHETEVKKLRLRVEELKKELAQAEDELDEAHNQARKLQRSLDEQTEQSENLQVQLEHLQSRLR-----RQQQNAPLFGKIR--------------------------STRFGTEEAGDGASDL---DEDED--LQIQVA------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TMW1-1", "uniprot_id": "C102A_MOUSE", "id": "Q3TMW1-1", "name": "Coiled-coil domain-containing protein 102A", "aln": "MSHGPSPRLAESPQLSKSSLLTILGSPSPERMGPADSLPPTPPSGTPSPGPPPSLPLT-APALLADGDWESREELRLRELEEARARALQMEKTMRWWSDCTANWREKWSKVRAERNRAREEVRQLRQRLDTLTKELAGARRERQEAQGECEARGRELARLR-------GVHSAADKTHDGPEPER--------------------------------EQEPVRDIGAERPPGSQ-ELDLVESLLKSRPEEPEGCWDAC---SVAAGGPRVSSGRQDRNRLPWEDTASTEED--ASKLTALRLRLDESQKVLLKEREDKLALSKNIEKLEGELSQWKIKYEELSKTKQEMLKQLSILKETHQDELGRMSEDLEDELGARSSMDRKMAELRGEMERLQAENAAEWGRRERLETEKLGLERENKKLRAQVGDLEEALARRRRQNASALDCDLRASQAALFEKNKELADLKHVHGKLKKQFQEKVAELAHANRRVEQHETEVKKLRLRVEELKKELAQAEDELDEAHNQARKLQRSLDEQTEQSENLQVQLEHLQSRLR-----RQQQNAPLFGKIR--------------------------STRFGTEEAGDGASDL---DEDED--LQIQVA------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96A19-1", "uniprot_id": "C102A_HUMAN", "id": "Q96A19-1", "name": "Coiled-coil domain-containing protein 102A", "aln": "MSHGPSPRLAESPQLSKGSLLTILGSPSPERMGPADSLPPTPPSGTPSPGPPPALPLPPAPALLADGDWESREELRLRELEEARARAAQMEKTMRRWSDCTANWREKWSKVRAERNRAREEVRQLRQRLDALTKELAGARRERQEAQGECEARGRELARLR-------GARGVADQTRDGPEPEA--------------------------------EREPVRDVGSERPPGSQ-ELELVESLLKSMPEESEDCWEAR---SLGAGGPRGSSGRQERSRLPWEDTAATEEE--ASKLTALRLRLDESQKVLLKEREDKLALSRNIEKLEGELSQWKIKYEELSKTKQEMLKQLSILKEAHQDELGRMSEDLEDELGARSSMDRKMAELRGEMERLQAENAAEWGRRERLETEKLGLERENKKLRAQVGDLEEALARRRRQTASALDCDLRASQAALFEKNKELADLKHVHGKLKKQFQEKVAELAHANRRVEQHEAEVKKLRLRVEELKKELAQAEDELDEAHNQARKLQRSLDEQTEQSENLQVQLEHLQSRLR-----RQQQNAPLFGKIR--------------------------SARFGTEEAEDGTSDL---DEDED--LQIQVA------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NZW0-1", "uniprot_id": "C102A_DANRE", "id": "Q6NZW0-1", "name": "Coiled-coil domain-containing protein 102A", "aln": "MNHTPSPHMTEAAKSGAG-LLCGLG-LGPDRVRSPDSLTHTPSPSGGTPSSSPPLLLSPGLGCDGIGDWESREELRLRELEEARARAAQMEKTMRWWSDCTANWREKWSKVRAERNRARDEVRQLRQRLDALTKELTGARRERQELAAENEQLRLEAQRVR-------AEQSSPENASTAPESISSTASTHSNQPREAEIKQDNQDEEGVRDGPGSPEQEPVRDIGTDKLYKQK-EMELLEALLRAKSEAP-DSWDGR---SASS--LRSALSRQDRNRLLWEDLAALEED--TSKLNALQLRLDESQKVLLKEREDKHALIKNIEKLEAELSQWKLKYEELNKSKQEALKQLNLLKEVHQDELGRMSEDLEDELGARTNMDKKLAELRTEMERLQVENAAEWGRRERLETEKLALERENKKLRTQMEDLEEQLARKRRQAASALDTDLKTIQSELFERNKELADLRHVHSKVKKQYQEKMAELTHANRRVEQHEAEVKKLRLRVEELKKELGQAEDELDEAHNQTRKLQRSLDEQVEQSENLQVQLEHLQSRLR-----RQQ-NPGLFGKMRTSA-----------------------SSRFGPEDADGPPSDP---DEDEEEELQLQIP------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMC7-1", "uniprot_id": "Q9VMC7_DROME", "id": "Q9VMC7-1", "name": "Coiled-coil domain-containing protein 102A", "aln": "MSQTASTTQSVTAAPAGG--------SRRNEVGGVGVIGTTMS------------------ARYGETEWEARESQRQRELHEARARAAQMEKTMKWWSDCTANWREKWSKVRNERNKAREESKQLSLKLDGVMKEAHSLKREKNDLELQITQLKKEMEKVHTLMMKHAGQFHRADTSEDAEANGR--------------------------------DANCSPDISSDGLKNINSEDGLVTKLPNDVKDLDIEEFAMKGAMPKHLTELDEAAAAEEKRLIQQLSKDDFDEDYLLQKISMLQLRLDEAQKTLQAERDEKLELHKSIEKLTLEIQDVRGRQEEMRSAKQEAVRELLTLQEQHRAEMRIVNNSLQEEIAARENLERRLTELRTELEHLQAENASEWGKRERLESEKLAMERDNKKLRAELRDYQERSDRKCRP-MQANDVELRALQQELSERNKEISEVKMSHAKLKKLLAETNTELGHAVRRAEQYEAEVKRLRQRVEELKRELAGAEDELDSAVNQVRRLQRSNDELVGQTEGLQVQIQHLQNRRAPSPQLRGMGGVQLRNKIAVELPNDCLPNINDLRQIFDDSQAGLRSSHNGSDAAMHHAASVKRSSHTERTLLQQQQSSAAASAAAAAAAAAAFFDAKPTHLEENIFESKSRNLEFERAKQKFDNPHGQHHHHHQRQRSGNGRYGSAGSSASRANLALPLKGTTNGGSSSVSSKDELNRQLYEKEQSAGAGYARNSINLDGLKVSDDETP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: .*. : :. . . :.: . : * . . . :**:**. * ***.****** ******: **************** ***:**:* :** :** : ** . :**::: : * ::: . .: : . : : *:.:: : * *: * . : : . : . ::: : . :*: .*:. *:*****:**.* **::* * :.**** *:.: : : **: .:*** :::* *:* *: *: :.:.*::*:.** .::::::*** *:*:**.***:***:*****:***.:**:*****::: * :* *: * .* * :*:: * * *:***::::: *.*:** *. :** ** **.**:*:***:** ******:**. ******.* **.*:**** ** . *:*.****::***.* * . * .*: *:: *.: * .:. .. * ** * . ", "identical_positions": 196, "similar_positions": 157, "identity": "25.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-405", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LM38-1", "uniprot_id": "F1LM38_RAT", "id": "F1LM38-1", "name": "KH homology domain-containing protein 4", "aln": "MSAGSATHPAAGGRRSKWDQPAPAPLLFLPPAAPGGEVTSSGGSPGGAST-AAPSGALDAAAAVAAKINAMLMAKGKLKPSQNAAEKLQAPGKSLTSNKSKDDLVVAEVEINDVPLTCRNLLTRGQTQDEISRLSGAAVSTRGRFMTTEEKAKVGPGDRPLYLHVQGQTRELVDRAVNRIKEIITNGVVKAATGTSPTFNGATVTVYHQPAPIAQLSPAVNQKPSFQSGMHYVQDKLFVGLEHAVPTFNVKEKVEGPGCSYLQHIQIETGAKVFLRGKGSGCIEPASGREAFEPMYIYISHPKPEGLAAAKKLCENLLQTVHAEYSRFVNQINTAVPLPGYTQPSAISSIPPQPPYYPSNGYQSGYPV-VPPPQQPVQPPYGVPSIVPPAVSLAPGVLPALPTGVPPVPTQYPITQVQPPASTGQSPISAPFIPAAPVKTALPAGPQPQPQP--PLPAQPQSQKRRFTEELPDERESGLLGYQHGPIHMTNLGTGFSS-QNEIEGAGSKPASSSGKERERDRQLMPPPAFPVTGIKTESDERNGSGALTGSHDYPAKKMKTAEKGFGLVAYAADSSDEEEEHGGHKNASSFP----QGWSLGYQYPSSQPR----------AKQQMPFWMAP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TCX3-1", "uniprot_id": "KHDC4_MOUSE", "id": "Q3TCX3-1", "name": "KH homology domain-containing protein 4", "aln": "MSAGSATHPAAGGRRSKWDQPAPAPLLFLPPTAPGGEVAGSGASPGGATTAAAPSGALDAAAAVAAKINAMLMAKGKLKPSQNAAEKLQAPGKSLTSNKSKDDLVVAEVEINDVPLTCRNLLTRGQTQDEISRLSGAAVSTRGRFMTTEEKAKVGPGDRPLYLHVQGQTRELVDRAVNRIKEIITNGVVKAATGTSPTFNGATVTVYHQPAPIAQLSPAINQKPSFQSGMHYVQDKLFVGLEHAVPTFNVKEKVEGPGCSYLQHIQIETGAKVFLRGKGSGCIEPASGREAFEPMYIYISHPKPEGLAAAKKLCENLLQTVHAEYSRFVNQINTAVPLPGYTQPSAISSIPPQPPYYPSNGYQSGYPV-VPPPQQPVQPPYGVPSIVPPAVSLAPGVLPALPTGVPPVPTQYPITQVQPPASTGQSPISAPFIPAAPVKTALPTGPQPQPQ----LPAQPQSQKRRFTEELPDERDSGLLGYQHGPIHMTNLGTGFSS-QNEIEGAGSKPASSSGKERERDRQLMPPPAFPVTGIKTESDERNGSGALAGSHDYPAKKMKTAEKGFGLVAYAADSSDEEEEHGGHKNASSFP----QGWSLGYQYPSSQPR----------AKQQMPFWMAP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z7F0-1", "uniprot_id": "KHDC4_HUMAN", "id": "Q7Z7F0-1", "name": "KH homology domain-containing protein 4", "aln": "MSAGSATHPGAGGRRSKWDQPAPAPLLFLPPAAPGGEVTSSGGSPGGTTA--APSGALDAAAAVAAKINAMLMAKGKLKPTQNASEKLQAPGKGLTSNKSKDDLVVAEVEINDVPLTCRNLLTRGQTQDEISRLSGAAVSTRGRFMTTEEKAKVGPGDRPLYLHVQGQTRELVDRAVNRIKEIITNGVVKAATGTSPTFNGATVTVYHQPAPIAQLSPAVSQKPPFQSGMHYVQDKLFVGLEHAVPTFNVKEKVEGPGCSYLQHIQIETGAKVFLRGKGSGCIEPASGREAFEPMYIYISHPKPEGLAAAKKLCENLLQTVHAEYSRFVNQINTAVPLPGYTQPSAISSVPPQPPYYPSNGYQSGYPV-VPPPQQPVQPPYGVPSIVPPAVSLAPGVLPALPTGVPPVPTQYPITQVQPPASTGQSPMGGPFIPAAPVKTALPAGPQPQPQPQPPLPSQPQAQKRRFTEELPDERESGLLGYQHGPIHMTNLGTGFSS-QNEIEGAGSKPASSSGKERERDRQLMPPPAFPVTGIKTESDERNGSGTLTGSHDYPAKKMKTTEKGFGLVAYAADSSDEEEEHGGHKNASSFP----QGWSLGYQYPSSQPR----------AKQQMPFWMAP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NZ18-1", "uniprot_id": "KHDC4_DANRE", "id": "Q6NZ18-1", "name": "KH homology domain-containing protein 4", "aln": "MSFG--VPHSGGSRRSKWDQAG--------PDADAG---------------SAPTGALDAAAAVAAKINAMLVAKGKLKPSQISSAAPVDKAAGAGGNKLKDDLVVAEVEINDVPLTCRNLLTRGQTQDEISRVSGAAVSTRGRFMTVEEKSKALPSDRPLYLHVQGQTRDLVDKAVNRIKEIITNGVVKAATNS--TYSGATVTVYQQSGPSVPTIPSAPHKPHYPGGMHYVQDKVFVGLDQALQGFNVKERVEGPSCSFLQHIQAETGAKVFLRGKGSGCLEPASGREAFEPMYIYISHPKPEGLASAKTLCENLLQTVHAEYSRYLNQMSSMMPTQGFIHPPVVNGLPPQPPYYSPAGFQPSYPAPVPPPPPPIAPQYPVAPVAP-----AP---------VPPPNAQYPITPVPAHVPT-QTLLPAAFPPTAPVPPKLTAPPNP-------------PQKRRFTEEV-DEMDRGLLGYQHGPIHMTNLGAGMPVGSSETSGPPSAASSVPVRERDSSRQLMPPPCAPALLKPLRPLKADESPSAPSLLEPQVKRMRT-----GLVAYAGDSSDEEEDHGPSRAAVTAAGNPGAGWNP-YRCPPSPPHRPKTQTAPQPTQQNMPFWMAP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * . ..*.*******.. * * .* **:*****************:*******:* :: . . .** *********************************:*************.***:*. *.*************:***:******************.: *:.*******:*..* . *: :** : .********:****::*: *****:****.**:***** ***************:*************************:**.***************::**:.: :* *: :*..:..:*******.. *:*..**. **** *: * * *..:.* ** *** :***** * . ..* *: : ..* *:*** . *.: *:* .********: ** : ****************:*:. ..* .*. * .:* . :**: .*******. *. .. : : * : .. : .*:*:* ******.*******:** : * : . **. *: *.* *: ::*:*******", "identical_positions": 348, "similar_positions": 123, "identity": "55.06%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4053", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q86V40-1", "uniprot_id": "TIKI1_HUMAN", "id": "Q86V40-1", "name": "Metalloprotease TIKI1", "aln": "-----MSPWSWFLLQTLCLLPTGAASRRGAPGTANCELKPQQSELNSFLWTIKRDPPSYFFGTIHVPYTRVWDFIPDNSKEAFLQSSIVYFELDLTDPYTISALTSCQMLPQGENLQDVLPRDIYCRLKRHLEYVKLMMPLWMTPDQRGKGLYADYLFNAIAGNWERKRPVWVMLMVNSLTEVDIKSRGVPVLDLFLAQEAERLRKQTGAVEKVEEQCHPLNGLNFSQVIFALNQTLLQQESLRAGSLQIPYTTEDLIKHYNCGDLSSVILSHDSSQVPNFINATLPPQERITAQEIDSYLRRELIYKRNERIGKRVKALLEEFPDKGFFFAFGAGHFMGNNTVLDVLRREGYEVEHAPAGRPIHKGKSKKTSTRPTLSTIFAPKVPTLEVPAPEAVSSGHSTLPPLVSRPGSADTPSEAEQRFRKKRRRSQRRPRLRQFSDLWVRLEE--SDIVPQLQVPVLDRHISTELRLPRRGHSHHSQMVASSACLSLWTPVFWVLVLAFQTETPLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F6V0-1", "uniprot_id": "TIKI1_DANRE", "id": "E7F6V0-1", "name": "Metalloprotease TIKI1", "aln": "MTMMTMMMVSWSAFLQICWILMVRANQFNPGEPSGCRTNTPQSDLNSFLWTIKRDPPSYLYGTIHVPYTRVWDFIPQNSKQAFQESSVVYFELELTDPSTISALSRCQLLPAGQNLQDVLPPELYLRLKTHLEYVRLMLPSWMTPDQRGKGLYAEYLFNAIAGNWERKRPVWVMLMVNSLTEADIKTRGVPVLDLYLAQEAERMKKQTGAVEKVEEQCSPLNTLDFSQVIFALNQTLLQQESVRAGSLQVPYTTEHLITHYNCGDLHS-IISHDTAQVPNFNNVTLRPSDQVTAQQIDSYFRRELIYKRNERMGRRVTALLQEQPHKTFFFAFGAGHFLGNNSVIDVLRREGYEVEHTPAGQPLHR-RSGWRSADP---------ADTDAALQPFLHHSRHHELQLLEG----LELLEKVEHKLKKKHRRNKLK-KQRQFNDLWVRMEDSVTAEAPPPLIHIINGYITVQTHPQEHERANHDRTFSGSS--SRTGPALSALAVCVQMLRLLL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ** : :* : *.: .. .:.*. :. **:***************::***************:***:** :**:*****:**** *****: **:** *:******* ::* *** *****:**:* *************:***************************.***:********:*******::************* *** *:*****************:******:*****.**.******* * *:***::***** *.** *.:::***:****:***********:*:**.***:* *.* **********:***:*:************:***:*:*: :* *: * . * . * * * * * . : .:.*::::**:**.: : : ***.*****:*: : .* : ::: :*:.: : .: :::*.: .:.*: * *.: .*.:..* **", "identical_positions": 300, "similar_positions": 111, "identity": "58.59%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4075", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UEI1-1", "uniprot_id": "PDE4C_MOUSE", "id": "Q3UEI1-1", "name": "3',5'-cyclic-AMP phosphodiesterase 4C", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRRSGTALSFLWTERVREPVDSGVAPVSPLG---GGVILRRFSGTLLLPPLSSRLGSSGEAESAAHVVFTIGTQGTQRNLG-------------------SAQSSFDLENGLPGGKGLLDAQSGPSLGRALQPPVHHVQRRESFLYRSDSDHEPSPKAVSRTSSAASD-------------LHGEDMIVTPFAQVLASLRTVRNNVAALAHGPGS-ATRQVLLGTPPHSSQQAA-----PTEDSGLQLVQETLEELDWCLEQ-LETLQTRRSVGEMASNKFKRMLNRELSYLSETSRSGNQVSEYISQTFLDQQAEVELPQPPTEDDP-------------------------WPMAQITELRR-SSHTS-LPTAAIPRFGVQTDQEEQLAKELEDTNKWG------LDVFKVAELSG-NRPLTAVIFSVFQERDLLKTFQIPADTLLAYLLTLEGHYHSDVAYHNSMHAADVVQSAHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFRNLSTKQRLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPAKPLPLYRQWTERIMAEFFQQGDRERESGLDISPMCDKHTASMEKSQVGFIDYIAQPLWETWADLVHPDAQELLDTLEDNREWYQSRIPCSP-----PHTMGS--------DRFKFELTLEEAEEE-EEEEDEGQCT-ALNRESSELPST-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14644-1", "uniprot_id": "PDE4C_RAT", "id": "P14644-1", "name": "3',5'-cyclic-AMP phosphodiesterase 4C", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NSSRTSSAASD-------------LHGEDMIVTPFAQVLASLRTVRSNVAALAHGAGS-ATRQALLGTPPQSSQQAA-----PAEESGLQLAQETLEELDWCLEQ-LETLQTRRSVGEMASNKFKRMLNRELTHLSETSRSGNQVSEYISQTFLDQQAEVELPAPPTEDHP-------------------------WPMAQITGLRK-SCHTS-LPTAAIPRFGVQTDQEEQLAKELEDTNKWG------LDVFKVAELSG-NRPLTAVIFRVLQERDLLKTFQIPADTLLRYLLTLEGHYHSNVAYHNSIHAADVVQSAHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFQNLSTKQKLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPAKPLPLYRQWTERIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQELLDTLEDNREWYQSRVPCSP-----PHAIGP--------DRFKFELTLEETEEE-EEEDERH-----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08493-1", "uniprot_id": "PDE4C_HUMAN", "id": "Q08493-1", "name": "3',5'-cyclic-AMP phosphodiesterase 4C", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENLGVGEGAEACSRLSRSRGRHSMTRAPKH---LWRQPRR-PIRIQQRFYSDPDKSAGCRERDLSPRPELRKSRLSWPVS-------------------SCRR-FDLENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASD-------------LHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAAKQGPVGNPS-SSNQLP-----PAEDTGQKLALETLDELDWCLDQ-LETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAP-------------------------QPMSRISGLHG-LCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWG------LDVFKVAELSG-NRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGP--------DRFQFELTLEEAEEEDEEEEEEGEET-ALAKEALELPDTELLSPEAGPDPGDLPLDNQRT----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U285-1", "uniprot_id": "A0AB32U285_DANRE", "id": "A0AB32U285-1", "name": "Phosphodiesterase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEN----------MRQRDSLISSPLELQSKT---SSAIRRRFSGPLLLPPLARR--HSALDGKKLKDLEALYKSALARADT-------------------QKETDFDVENGLSMGRSSLDP--SPSSGLVLQA---NSQRRESFLYRSDSDFDLSPKTMSRNSSTASE-------------LHGEDMIVTPFAQVLASLRTVRGNVAALTHMQDR--SNKRPSGTNPQSACKTN-----LSDEAYQKLTVETLEELDWCLDQ-LETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEFIASTILQKQYDVELLSAACKEEKK-----------------------RRPMSQISGVRK-LSPSPSLPPTCIPRFGVNTQHESLLAKELEDLDRWG------IDIFKIAEYSG-NRPLTVMMYTIFQERDLLKTFKIPSDTFLTFLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEDVFTDLEIMAALFASAIHDVDHPGVTNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFCNLSKKQRQSLRQMTIDMVLATDMSKHMNFLADLKTMVETKKVTSQGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFSQGDRERDKGIDVSPMCDKHTASMENTQVGFIDYIIHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSPTPEEHDSRPTGVTGSAGEKFQFELTLEEEDGELETEEEHTDIERSRTMTDPEHPQTSPLGITTILDSSERELDQELTSVSALQLETSSSSTHD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4T4-1", "uniprot_id": "PDE4A_DROME", "id": "Q9W4T4-1", "name": "3',5'-cyclic-AMP phosphodiesterase, isoform I", "aln": "MMRLARFTQGFSFNKNVAKHRGSGSSNGTGNGSGTGNGQGLGGSCSANGLAATGGVGGGGGSGSGGGGCGSGSGSGSGKRKSKARTKCFGGTVFRCCLPCRGGGSAAPATSPPQTPAQTPDELKVIPEDCNLEKSAEQKRDLLERNNKEDDLLNRTVSGSELDLYGGAGGGTKKHSLADTIDTSVTTPISLKTLINDVDEELDQQLSAADIAAASLASGLVARRAEPETLSDASVSPTAVVQQQQQQQQQLQQPLLQSQPHFVPSSGNILSQVTLYSGSNPSTNPCQSAVQNQGQNSNPNPNQNPNTNPNQNQQRCSCQPQTSPLPHIKEEEESDQANFKHQTSLKEHQPLPPPITIATGYCGSCESVHHSSATSSSAGTVPPGGQQTQEYIAGTSSTPSPRIKLKFRKPHKSCWSRIVLAPIGSAGGSSSATTVIGSNSNETLASSSTTGGTATTTQNSSSVSVAAHHRLTSSSASALATSHPSNSQLLPTSKMQAEQGSIGDLQKYHSRYLKNRRHTLANVRFDVENGQ-GARSPLEG-GSPSAGLVLQN---LPQRRESFLYRSDSDFEMSPKSMSRNSSIASERFKEQEASILVDRSHGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQ-LETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQISEYICSTFLDKQQEFDLPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPLSHTNSFTGERLPTFGVETPRENELGTLLGELDTWG------IQIFSIGEFSV-NRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMIPPSPPPSGVDENPQE--------DRIRFQVTLEESDQENLAELEEGDESGGESTTTGTTGTTAASALSGAGGGGGGGGGMAPRTGGCQNQPQHGGM---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06776-1", "uniprot_id": "PDE2_YEAST", "id": "P06776-1", "name": "3',5'-cyclic-nucleotide phosphodiesterase 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTLFLIGIHEIEKSQTIVQN-------------EHYFDRVIELQDLDSLMVALYKDRVSPFPNVHNFETGVSIVLYDPSKFQLSVR----QLDVLFKRFFPSFNISAIDHTREENLQRLECVERENSICRNRITRINHWMYHHHDDTPDG-------INKNSYGTVNGNSVPTQACEANIY---------------------------TLLLHLND--SKAQHLRKASVPRLIRNIEFMSFLSDPIEKISQEGSHYWNILSTWDFCALSLSTQELIWCGFTLIKKLSKDAKVLIADNKLLLLLFTLESSYHQVNKFHNFRHAIDVMQATWRLCTYLLKDNPVQTLLLCMAAIG---HDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHRELFQQLLSEHWPQLLSISKKK-----FDFISEAILATDMALHS---------------QYEDRLMHENPMKQITLISLIIKAADISNVTRTLSISARWAYLITLEFN---DCALLETFHKAHRPEQDCFGDSYKNVDSPKEDLESIQNILVNVTDPDDIIKDHPHIPNGQIFFINTFAEVFFNALSQKFSG----------LKFLSDNVKINKEYWMKHKKPQ----------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:..: ..: * * :: : :..: .:.. . . : .:. :* :: *: :: . ..:. ::.*: : .::. . * . .: : : : :. . : : :* : : . *. : . . * :. :.. * .: * : :::. . .. *. ..: : **. * :** ** ** *:: * : . * : * :. ***.*** .**:* * .**:* ::: *:***.* : :**. . ::: . * : : :*:***: * . *: :* .:* ::. :::.**:** ::.* : :*. : ** * . :. : ::. . .:*. . ..: : .::..** .. * : : . . ::* : : * : .. ", "identical_positions": 69, "similar_positions": 171, "identity": "5.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4076", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NS46-1", "uniprot_id": "RRP5_MOUSE", "id": "Q6NS46-1", "name": "Protein RRP5 homolog", "aln": "------------------------------MANLEESFPRGGTRKLHKSEKSSQQVVEQDNLFDVS-----TEEGPIKRKKS-QKGPAKTKKLKIEKRKSIKSIKEKFEILSLESLCEGMRILGCVKEVSELELVVSLPNGLQGFVQVTEVCDAYTQKLN-----------------------------EQVAQEEPLEDLLRLPELFSPGMLVRCVVSS-----LDVTESGKKSVKLSVNPKRVNKVLSADALRPGMLLTGTVSSLEDHGYLVDIGVGGTRAFLSLKKAQEYIRQKNKGAKFKVGQYLTCVVEEVKSNGGVVSLSVEHSEVSSAFATEEQSWNLNNLLPGLLVKAQVQKVTQFGLQLNFL-TFFKGLVDFMHLE--PKKMGSYSSNQTVKACILCVHPRTRVVRLSLRPIFLHPGRPLTRISYQQ-------LGAVLDDVPVQGFFKNAGAIFR--LKDGVLAYARVS-HLSDSKKAFN-AEAFKPGSTHKCRIIDYSQMDELALLSLRKSIIAAPFLRYHDIKIGTVVKG-TVLAIK-PFGILVKVG-EQIKGLVPSMHLADIMMKNPEKKYSPGDEVKCRVLLCDPEAKKLIMTLK--KTLVTSKLSLITCYEGAK----PGLQTHGVIIRVKDYGCIVKFYNDVQGLVPKHELSTQHIPDPETVFYTGQVVKVAVLSCEPSKERMLLSFRLLSDSRPKDPGVESSQKKTGAVRIG-QLVDVKVLEKTKTGLEVAILPHNTPAFLPTPHLSD-HAANGPLLHHWLQTGDTLHRVLCLSQSERH-ILLCRKPALVSTVEGGQDPKSLSEIQPG---MLLIGFVKCIKEYGVFVQFPSGLSGLSPKTIMSDKFVTTPSEHFVEGQTVVAKVTNVDESKQRMLLSLRLSDCSLGDSASTSFLLLCQCLEELQGIRSLMSNQ-DSVLIQTLADMTPGMVLDAVVHEVLEDGSVVFSSDPVPDLVLRASRYHRAGQEVEPGQKKKVVVLHVDMLKLEVHVSLHQDLVNRKTRKLRKSSRHQGIVQHLEESFAVASLVETGHLVAFSLISHLNDTFHFDSEKLRVGQGVCLTLKTTEPGVTGLILAVEGPASKRTRMPVQRDSETVDDKGEEKEEEEEEEEKEEENLTVKSKKRHSLAIGDKVTGTIKAVKATHVVVTLADGFVGCIHASRILDDVPVGTSPTTTLKAGKKVTARVIGGRDVKTSKFLPISHPRFVLTILELSVRPSELKGSYSALNTHSESPVEKIRQYQAGQTVTCFFKKYNVMKKWLEVDIGPDIRGRIPLLLTSLSFKVLKHPDKKFQVGQAIEATVVDPDVPR-AFLCLSLIGPYRLEEGEVAMGRVMKVVPNRGLTVSFPFGKIGKVSMFHLSDSYSEAPLEDFCPQKIVRCYILSTAHR-VLALSLRSSRTNRETKNRIEDPEINSIEDVKEGQLLRGYVKCVLPSSVIIGLGPSVLGLAKYSHVSECVPPEKELYNGCLPEGKLVTAKVLRVNPMKNLIELSLLPSDTGRPDVFSPAPEP---KQEERSGGAEE-GQK--------RKEKNQKRREE-------KEEPQKSQRGGRGKRERQESESEQELVNKRPKKSGAAEEDDSGVEVYYREGEDEVGEPKLPPRGKQTKSTEVPRLHLSSGFLWDVGLDSLTPALPLREESSDSE-DEQPHQAKKKKGKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKYKEAGELYNRMLKRFR-QEKAVWIKYGAFVLGRSQAGASHRVLQRALECLPAKEHVDVIVKFAQLEFQLGDVERAKAIFENTLSTYPKRTDVWSVYIDMTIKHGSQTAVRDIFERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAKALEYVEAKSSALED-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZNI3-1", "uniprot_id": "D3ZNI3_RAT", "id": "D3ZNI3-1", "name": "Protein RRP5 homolog", "aln": "------------------------------MANLEESFPRGGTRKPHKSEKSSQPVVEQDNLFDIS-----TEEGSVKRKKS-QKGPAKTKKLKIEKRKSNKSMKEKFEILSLESLCEGMRILGCVKEVNELELVVSLPNGLQGFVQVTEICDAYTQKLN-----------------------------EQVAQEEPLEDLLRLPELFSPGMLVRCVVSS-----LDVTESGKKSVKLSVNPKRVNKVLSAEALRPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLSLQKAQEYIRQKNKGAKFKVGQYLTCVVEELKSNGGVVSLSVEHSQVSSAFATEEQSWNLNNLLPGLVVRAQVQKVTQFGLQLNFL-TFFTGLVDFMHLE--PKKMGSYSSKQTVKACILCVHPRTRVVRLSLRPIFLHPGRPLTRISYQQ-------LGTVLDDASVEGFFEKAGAIFR--LRDGVLAYARLS-HLSDSKKAFS-AEAFKLGSTHRCRIIDYSQMDELALLSLRKSIIAAPFLRYQDIKTGTIVKG-KVLALK-PFGMLVKVG-EQMRGLVPSMHLADIMMKNPEKKFNTGDEVKCRVLLCDPEAKKLIMTLK--KTLVTSKLPAITCYEDAK----PGLQTHGVIIRVKDYGCLVKFYNDVQGLVPKHELSAQHIPDPERVFYTGQVVKVAVLNCEPSKERMLLSFKLLSGSEPKDESVKNSKKKGSTVNTGQQLVDVKVLEKTKNGLEVAILPHNIPAFLPTPHLSD-HVANGPLLHHWLQTGDTLHRVLCLSQSEKH-ILLCRKPALVSTVEGGQDPKSLSEIQPG---MLLIGFVKSIKDYGVFVQFPSGLSGLSPKTIMSDKFVTTPSEHFVEGQTVVAKVTNVDESKQRMLLSLRLSDCSLGDSASTSFLLLCQCLEELQGIRSLMSNQ-DSVLIQTLADMTPGMVLDAMVQEVLENGSVVFGGGPVPDLILRASRYHRAGQELEPGQKKKVVVLHVDALKLEVHVSLHQDLVNRKARKLRKNSRHQGIVQHLEESFAVASLVETGHLVAFSLISHLNDTFHFDSEKLRVGQGVCLTLKTTEPGVTGLILAVEGPASKRIRMPAQRDSETVDDKGEEEEEEEEED------LTVRSKKSHSLAIGDKVTGTIKSVKATHAVVTLDDGFIGCIHVSRILDDVPEGVSPTTTLKAGKKVTARVIGGRDVKTSKFLPISHPRFVLTILELSVRPSELKGDYRALNTHSVSPMEKIRQYQAGQTVTCFLKKYNVMKKWLEVDIEPDIRGRIPLLLTSLSFKVLKHPDKKFQIGQAIKATVVGPDIPR-AFLCLSLIGPYKLEEGDVAMGRVLKVLPNKGLTVSFPFGRIGKVSVFHLSDSYSEEPLTDFCPQKIVRCYILSTAHR-MLALSLRSSRTNKETKSKIEDPEVNSIEDIQAGQLLRGYVKSILPSSVVIGLGPSVMGLVKHSHVSQCVSREKELYDKCLPEGKLVTARVLCVNPKKNLIELSLLPSDTGKPDVFSASPEPPLPKQEGREGGTEK-GLKGESKRSQRRREKNQKMREESGLYSQEKKEPRKSQRGGQSKRERQESESEQELVNKRPKKSGAPEDDDSGVEVYYREGEDEVEEPKVPPGGKQSKPTEVPRLQLSKGFIWDVGLDSLTPALPLRGESSDSEEDEQPHQAKKKKGKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLAKVFERAVQYNEPLKVFLHLADIYTKSEKFKEAGELYNRMLKRFR-QEKAVWIKYGAFVLGRSQAGASHRVLQRALECLPTKEHVDVIVKFAQLEFQLGDVERAKAIFENTLTTYPKRTDVWSVYIDMTIKHGSQKEVRDIFERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAKALEYVEAKSSALEDQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14690-1", "uniprot_id": "RRP5_HUMAN", "id": "Q14690-1", "name": "Protein RRP5 homolog", "aln": "------------------------------MANLEESFPRGGTRKIHKPEKAFQQSVEQDNLFDIS-----TEEGSTKRKKS-QKGPAKTKKLKIEKRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGFVQVTEICDAYTKKLN-----------------------------EQVTQEQPLKDLLHLPELFSPGMLVRCVVSS-----LGITDRGKKSVKLSLNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNKGAKLKVGQYLNCIVEKVKGNGGVVSLSVGHSEVSTAIATEQQSWNLNNLLPGLVVKAQVQKVTPFGLTLNFL-TFFTGVVDFMHLD--PKKAGTYFSNQAVRACILCVHPRTRVVHLSLRPIFLQPGRPLTRLSCQN-------LGAVLDDVPVQGFFKKAGATFR--LKDGVLAYARLS-HLSDSKNVFN-PEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDIEPGAVVKG-TVLTIK-SYGMLVKVG-EQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLK--KTLIESKLPVITCYADAK----PGLQTHGFIIRVKDYGCIVKFYNNVQGLVPKHELSTEYIPDPERVFYTGQVVKVVVLNCEPSKERMLLSFKLSSDPEPKKEPAGHSQKKGKAINIG-QLVDVKVLEKTKDGLEVAVLPHNIRAFLPTSHLSD-HVANGPLLHHWLQAGDILHRVLCLSQSEGR-VLLCRKPALVSTVEGGQDPKNFSEIHPG---MLLIGFVKSIKDYGVFIQFPSGLSGLAPKAIMSDKFVTSTSDHFVEGQTVAAKVTNVDEEKQRMLLSLRLSDCGLGDLAITSLLLLNQCLEELQGVRSLMSNR-DSVLIQTLAEMTPGMFLDLVVQEVLEDGSVVFSGGPVPDLVLKASRYHRAGQEVESGQKKKVVILNVDLLKLEVHVSLHQDLVNRKARKLRKGSEHQAIVQHLEKSFAIASLVETGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVTGLLLAVEGPAAKRTMRPTQKDSETVD------EDEEVDP-----ALTVGTIKKHTLSIGDMVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGTSPTTKLKVGKTVTARVIGGRDMKTFKYLPISHPRFVRTIPELSVRPSELEDGHTALNTHSVSPMEKIKQYQAGQTVTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDKKFRVGQALRATVVGPDSSK-TLLCLSLTGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSIFHMSDSYSETPLEDFVPQKVVRCYILSTADN-VLTLSLRSSRTNPETKSKVEDPEINSIQDIKEGQLLRGYVGSIQPHGVFFRLGPSVVGLARYSHVSQHSPSKKALYNKHLPEGKLLTARVLRLNHQKNLVELSFLPGDTGKPDVLSASLEGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFR-QEKAVWIKYGAFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTDVWSVYIDMTIKHGSQKDVRDIFERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAKALEYVEAKSSVLED-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NCQ8-1", "uniprot_id": "A0A8M1NCQ8_DANRE", "id": "A0A8M1NCQ8-1", "name": "Protein RRP5 homolog", "aln": "------------------------------MASMEEDFPRGGTERKKPTDLIPH---EVDNLFDTP-----AKVVKKKKKSVKQDEAPKSKKQKVDEENIKLNTTTTVQILHLRDLTVGTLMLGCVKEVSDFEVVVGLPSGLVGYLPICNICDAYTNILN-----------------------------DKLDTDDGLEEVVPLSKLFTPGMLIRCVVSS-----LDSAKEGHISLKLSINPKDVNKALNSVALKPAMTLSGCVESVEDHGYLVDIGIGGTKAFLPKK-------STSSKQDLYVGQYVLVLIEDVKDSGRVVRLSQNPQALVKACAETKQGWTLDNLLPGLLIHGCVKRVTPHGLIVTFL-SSFTGVVDFLHLD--EDKESTYSKGQEILARILYVQPSTRQVGLSLRSHLLPPGGAVLDLHFSER------VGEVVQGCQMTSLHHYSGALMK--MLDGSRAFVHRN-LLKEPKEELD-TNHLMSQTQHILRIINYSPIEQIYQATLRWSSIETPFFSCQDIKVGQIVEG-TVTDLQ-KHGVYVRIG-EHIRGMIPRIHLADVTLKNPEKKFYPGLKVKCRVLSVEAQKKLLILTRK--KALVESTLPIFQSYSDAR----PGRISHGFVVCIKEFGCIVRFYEDVKGLVPMQELTTETVTNPEELFFVGQVVKVKVLKCDEEKKMLRLSFKSVTEEDVREE-----QIAKFDFIVG-KMVDARVCRKVLNGLEVSIIPEEVQAFLPTTHLSD-HVTNCLPLWMALEEGDTICNLMCLTNYKKKGIVLTKKPHLKAYIEDGAVPKNFSELQVG---MQMVGWVKNIMPYGVFISFPYGVFGLAPIANMGDQFIKETSGIFDIDQTVVAKVTNLDEEKQGFLVSLKLSELSLSENEFHTRLIQG--LKERRNISEMRAGRGDSDVLWKLSALTVGDQMKMIVGDTTEDGSVMLTSDQLSGVTVLASKYHKEGVNLTPGCKLNAVILHIDFVKSQVHVSLRPKLNIKKE-ELEKDARFTAKVQFADKDFAVVSLATTSDLTFFPTRPHLNS--IFDSKKFSVGS--CLDVKVDDP-------NCEDLAGFPLISYQSSN------------------------AKHEQHKPNEERLGELMKVTVKKLKALCVLVNLPSGNTGRVHVSQILEFPDIGSCPTSVLKVGMEMEARVIGGRAVRAHNFLAISHPDYNISIPELSFLESKLK---------VSDMVNKLEKYKPGDDIICFPSKYIKKEQLLEVHVKPDIMGAVPLLAMCNKLGLSKHPQRLFKPGQALSAKVVSVDPKKPIQFSLSLTGTHKLEPGMNTLAMVQKIQPHKGLMLALPYENTGLAHLTDLSDSYTEKPLESYKEGQIIRCHVIEQKIK-EFNVSLRPSRLNKDKHDIVEDPEIQSIADIKEGQSIRGYVSSVNDQGIFLRLSRTITGRVLFQNATKYYMNDPKVLIKHVGQNALVAAKVLSVDSENLHVNLSLLSKDTGKPDLLPESLELPLRLTGEEK---EKHDKKAAVKRKRTLSESQQQDNEN------TEQKTKRIKVDEECRLVEEPREQKETLKEKKKKKKSKKEDSDSGVEVFFRETDETVSDKKSGKVKVKCKEQEPNRLQVTSSFPWESTLGSLTPFAPADDNQNSSEDEEEVKSKPAKKSRKELKQEQQNTEQKPSKLEAELMDTSVRPDNSTAFERLLLSSPDSSLLWLQYMAFHLQATQIEQARAVAERALKTISFREEQEKLNIWVAMLNLENMYGTPDSLQKVFERAIQYCEPLLVYQQLADIYAKSEKIKEAESLYKSMVKRFR-QDKAVYLSYGTFLLRQRQSDAANALLQRALQSLSSKEHVDLIARFARLEFQFGNSEKAKSMFDKVLTTYPKRTDLWSVFIDLMVKHGSQKEVRELFDRVIHLSVSVKKIKFFFKRYLEYEKKNGTPETIQVVKQKALEYVESKGAEATS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05022-1", "uniprot_id": "RRP5_YEAST", "id": "Q05022-1", "name": "rRNA biogenesis protein RRP5", "aln": "MVASTKRKRDEDFPLSREDSTKQPSTSSLVRNTEEVSFPRGGASALTPLELKQVANEAASDVLFGNESVKASEPASRPLKKKKTTKKSTSKDSEASSANSDEARAGLIEHVNFKTLKNGSSLLGQISAITKQDLCITFTDGISGYVNLTHISEEFTSILEDLDEDMDSDTDAADEKKSKVEDAEYESSDDEDEKLDKSNELPNLRRYFHIGQWLRCSVIKNTSLEPSTKKSKKKRIELTIEPSSVN-IYADEDLVKSTSIQCAVKSIEDHGATLDVGLPGFTGFIAKK-------DFGNFEKLLPGAVFLGNITKKSDRSIVVNT-----DFSDKKNKITQISSIDAIIPGQIVDLLCESITKNGIAGKVF-GLVSGVVNVSHLR--TFSEEDLKHKFVIGSSIRCRIIACLENKSGDKVLILSNLPHILKLEDALR------STEGLDAFPIG--YTFESCSIK--GRDSEYLYLALD-DDRLGKVHSSRVGEIENSENLSSRVLGYSPVDDIYQLSTDPKYLKLKYLRTNDIPIGELLPSCEITSVS-SSGIELKIFNGQFKASVPPLHISDTRLVYPERKFKIGSKVKGRVISVNSRGNVHVTLKKSLVNIEDNELPLVSTYENAKNIKEKNEKTLATIQVFKPNGCIISFFGGLSGFLPNSEISEVFVKRPEEHLRLGQTVIVKLLDVDADRRRIIATCKVSNEQAAQQK------DTIENIVPGRTIITVHVIEKTKDSVIVEIPDVGLRGVIYVGHLSDSRIEQNRAQLKKLRIGTELTGLVIDKDTRTRVFNMSLKSSLIKDAKKETLPLTYDDVKDLNKDVPMHAYIKSISDKGLFVAFNGKFIGLVLPSYAVDSRDIDISKAFYINQSVTVYLLRTDDKNQKFLLSLKAPKVKE----------------EKKKVESNIEDP-VDSSIKSWDDLSIGSIVKAKIKSVKKNQLNVILAANLHGRVDIAEVFDTYEEITDK----------------------KQPLSNYKKDDVIKVKIIGNHDVKSHKFLPITHKISKASVLELSMKPSELKS-----------------------------------------------------------------------KEVHTKSLEEINIGQELTGFVNNSSGNHLWLTISPVLKARISLLDLADNDSNFSENIESVFPLGSALQVKVASIDREHGFVNAIGKSHVDINMSTIKVGDELPG--------RVLKIAEKYVLLDLGNKVTGISFITDALN-DFSLTLKEAFEDKINNVIPTTVLSVDEQNKKIELSLRPATAKTR------------SIKSHEDLKQGEIVDGIVKNVN-DKGIFVYLSRKVEAFVPVSKLSDSYLKEWKKFYKPMQYVLGKVVTCDEDSRISLTLRESEINGDLK------VLKTYSDIKAGDVFEGTIKSVTDFGVFVKLDNTVN-VTGLAHITEIADKKPEDLSALFGVGDRVKAIVLKTNPEKKQISLSLKASHFSKEAELAS-------------------------------------------------------TTTTTTTVDQLEKEDEDEVMADAGFNDSDSESD-------IGDQNTEVADRK--------PETSSDGLSLSAGFDWTA---SILDQAQEEEESDQDQEDFTENKKHKHKRRKENVVQDKTIDIN-----------TRAPESVADFERLLIGNPNSSVVWMNYMAFQLQLSEIEKARELAERALKTINFREEAEKLNIWIAMLNLENTFGTEETLEEVFSRACQYMDSYTIHTKLLGIYEISEKFDKAAELFKATAKKFGGEKVSIWVSWGDFLISHNEEQEARTILGNALKALPKRNHIEVVRKFAQLEFAKGDPERGRSLFEGLVADAPKRIDLWNVYVDQEVKAKDKKKVEDLFERIITKKITRKQAKFFFNKWLQFEESEGDEKTIEYVKAKATEYVASHESQKADE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VC94-1", "uniprot_id": "RRP5_DROME", "id": "Q9VC94-1", "name": "rRNA biogenesis protein RRP5", "aln": "------------------------------MVPNEKSFPRGGTIHS----EVKTDDVSLNIVFGAS-----------QKKVKKAPKVKENLLSYETEEQNGQLEAFSAETLNMDTLQEDMLVMGVVKELTATALQIALPGRMFARTLVADISDAYTRVAK-------------------------------AAMSGDTSEYHDLTELFQLGRIVYGKAIK-----TEKLDTGRVSLLLSLKPADVHGNLHHKSIKKGFIFSGAVAEALEHGYVIESGVQGLQAFVPCEK---------PAQKLHVGQLAFLKVKTVHHDTHQSTCTCVQVEQDQLRIKSQNETNLDYILPGSIVKFKVAKHLKDGLKGSIMNESFSAYVNEHHLANALDTLDAYELNEDYNARVLYVMPLTKLVYLTLNLDIKTGAAVAKDQDEEEQEVEPIKVGSVVEKAKVLRLGSGGVVLLLNKKLKGIISYGSIRGNFKGNYDKDEVLSKYGRKTKHKVRILGYDVIESLYYCSDDPNVVNEKLFCLEDINAGDLVTAKIFKKDDKIKGWSVRIG--KVNGILEQFYLA------PNVRYDVGQSLKCRVLEVNAERKICYVSNR--AEYLGKGIKILTDYASAH----VGNVYMGTVVRCEDTYVLVKFGNGIKGVLHRQNLKENSS------FFEGQTTKFRILTRNKDQITLTLPEDK--------------------FQLG-EICPVEITNALDAGLEVKIT------FAAEDDEEDEDGNPKLEEFVGLIPLRLLSDHLELLHAQMR--------------------------------------VHPAGSYTDAACIMQNIFSLRDVPYFSG-QLTKDWQSVQVGDIIRSYVKHATDQVVDLMVCVRN------------------------------------------YNKPVKVHVKMLRLNAVKNAPVELVPEQLLWVKVLSKEVETK------------------------------TLTVSAKLTDVWSGDLSDTAKLVEGYLNEVAQIKAG-------------------------------------------------------------------------------------LEEASAPISKYSVGEKINVVFKGIDATTNDWVYTVEGNGKVSALLLSSLVG-------------TAKAPEMGSKHEAVILWIEYSSDVLLISNKKLDIAHISPS-----------GELSTNLIGKAG-------MKAKVLLKLESVAVCSLKKGTNPLVICPIRLHPNDIEN----------------------------SGSAELRQGDFCN----------IAFIHDKLHIAVPETVWRLWRGVKRTAGTEVAPVKAKKAKVEESPKQ----------------------------------------------------KKTTIEETSAQKKVKAKAKVETKTEAKAIPTKRKAEVVEKITNGQKKTQPLTNGIVKE---------------------------------------------------------------KPKQNGKLFFEDKTPAKNAKSETPKSNG----------------------------------AEGKSRLPGVSSFWEDDVNQSKEGSSDEDEELNVAETQKNAAKKKRLSAKEKAKAEIKEEQRLREIEERNADPKARLETIDQYERLVIAQPNNSISWLKYIAFLLSNTEIEKARALARRAISTISFRETQELRNMWSALLNMELVYSN--NFDDVLKEALNCNDPLEIYISVVDILKKNKRKDRLSSVLTTVLNKFK-TELRVWPVAAEAYFWLGKSDQVHNLLQRALRALPNQEHIPCIVSFAKLYAKHDNNDMAQTLLDDVVTSYPKRIDIWSVYVDMLIKAGLIDSARNVLERAVVQKLKPNKMQVIYKKYLQLEENHGTDATVAKVKQQAEQWVKNYAKTVK--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .*****: . :: * . . : : : . * . ::* :. :. : : :.. : . : .:.: :* : .: * . * * : . . . : : *:::* *: : . : * . :** :: *: * .*:. .: * : : .:: ::** :: *: ..: ... *: ** . : : . : :: : : .. : . *::.*. ::.: : . : : .** * :: . . . * ::: :... : :::: *: :: * .:* **: :.. : : . : . * .*: . . : : :: * .:.*.: ::. : **.. . :* : .: : . . * : ..: . .: * : . . .* * : : . . : :: : . .* . . . .: : : . :. :::.:: . :. .. :: : : :. . * . : . . :*: :. .: . . : : . :.. . . :.. .. . * .: : . : : . . . *. * : : : . . : : :: : . . . . : : *: . . . . . . . * . :. . : ** . . : . :. ::**::..*:.*: *::*:** *. ::**:** :*.**:.**.*** * *:* *:**:* :.. .: .*:..* : :. :. : .* .:: .. .: . ::* . :: . : : . :* .**..*. ::*: : **:* .: : .::::: :: *** *:*.*::* :* ..::::* : .: :: :.:::::*: *:..* : ** :* ::* ", "identical_positions": 117, "similar_positions": 388, "identity": "5.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4078", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P158-1", "uniprot_id": "DHX57_HUMAN", "id": "Q6P158-1", "name": "Putative ATP-dependent RNA helicase DHX57", "aln": "MSSSVRRKGKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGG-GGGGGGGNRKASSRIWDDGDDFCIFSESRRPSRPSNSNISKG--------------------------ESRPKWKP-KAKVPLQTLHMTSENQEKVKALLRDLQEQ---DADAGSERGLSGEEED---DEPDCCNDERYWPAGQEPSLVPDLDPLEYAGLASVEPYVPEFTVSPFAVQKLSRYGFNTERCQAVLRMCDG----DVGASLEHLLTQCFSETFGERMKISEAVNQISLDECMEQRQEEAFALKSICGEKFIERIQNRVWTIGLELEYLTSRFRKSKPKESTKNVQENSLEICKFYLKGN-CKFGSKCRFKHEVPPNQIVGRIERSVDDSHLNAIEDASFLYELEIRFSKDHKYPYQAPLVAFYSTNENLPLACRLHISEFLYDKALTFAETSEPVVYSLITLLEEESEIVKLLTNTHHKYSDPPVNFLP---VPSRTRINN--------PACHKTVIPNNSFVSNQIPE--------VEKASESEE-SDEDDGPAPVIVENESYVNLKKKISKRYDWQAKSVHAENGKICKQFRMKQASRQFQSILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLN-GPPEKVANIICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMSATLNAELFSDYFNSCPVITIPGRTFPVDQFFLEDAIAVTRYVLQDGSPYMRS--MKQISKEKLKARRNRTAFEEVEEDLRLSLHLQDQD-SVKDAVPDQQLDFKQLLARYKGVSKSVIKTMSIMDFEKVNLELIEALLEWIVDGKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHSSLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPDERLTPLGYHLASLPVDVRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFAFANSDYLALLQAYKGWQLSTKEGVRASYNYCRQNFLSGRVLQEMASLKRQFTELLSDIGFAREGLRAREIEKR-AQGGDGVLDATGEEANSNAENPKLISAMLCAALYPNVVQVKSPEGKFQKTSTGAVRMQPKSAELKFVTKNDGYVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRVFIRDCSMVSVYPLVLFGGGQVNVQLQRGEFVVSLDDGWIRFVAASHQVAELVKELRCELDQLLQDKIKNPSIDLCTCPRGSRIISTIVKLVTTQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P5D3-1", "uniprot_id": "DHX57_MOUSE", "id": "Q6P5D3-1", "name": "Putative ATP-dependent RNA helicase DHX57", "aln": "MSSSVRRKGKPGKGDGKGSSRGGRGGKGHMNKSHGGGGGGGGSCGGGGGGSRKASNRIWDDGDDFCVFTEPKRPSRPCDSNKSKG--------------------------ETRPKWKP-KAKVPLQTLHMTSENQEKVKALLRDLQEQ---GADAGSERGTSGEEED---SEPQCG-EEQGWPAGQEPIFLPDCSPWEYIGPEEVEPPVPECAVSPLAVQKLSRYGFHTEHCQLALRICDG----DLGAALEHLLRQCFSETFGERMALSEAAVYVSLNECVEQRQEETLALKSICGEKFIERIQNRVWTIGLELDYLTNKFCKSKQKESSKNVRDTSPETCKFYLKGN-CKFGSKCKFKHEVPPHQMIGRAERNVNDPHLDADDDTTFMYELQIRFSKDHKYPYQAPLVAFYSTNENLPLACRLHISEFLYGKALEFAKTSEPVVYSLITLLEEESEIVKLLTHTQHKYSVPPVNVPP---VPSETRISK--------PAYRKPVVPSNTFLSNQMLE--------GERLSELEEDADEDEGPASIIVENESYVNLKKRSYKRYDRPAKSLFAENSKICRQFQMKQASRQFHAILQERQLLPAWEERETILKLLSKHQVVVISGMTGCGKTTQIPQFILDNSLN-GPPERVANIICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDATLQGVTHIIVDEVHERTEESDFLLLVLKDIVMQRATLQVILMSATLDAGLFSKYFSYCPVITIPGRAFPVDQFFLEDALAVTRYVLQDGSPYMRS--MKQIAKEKLKARHNRTAQEEVEEDLRLSLHLQDEEESVKDTIPDQQLDFKQLLIRYKGVSKSVIKTMSVMDFEKVNLELIEALLEWIVDGKHAYPPGAVLVFLPGLAEIKMLYEQLQSNSLFNNRRSHRCVIHPLHSSLSSEEQQAVFVKPPMGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDAGKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSTHNLQSVFSRLIEPPHIDSLRASKVRLRDLGALTPDEKLTPLGYHLASLPVDVRIGKLMLLGSIFRCLDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFAFANSDYLALLCAYKGWQLSTKESARASYNYCRQNFLSGRTLQEMASLKRQFTELLSDIGFVKEGLRAKEIEKR-AQGGDGVLDATGEEANTNAENPKLISAVLCAALYPNVVQVKTPEGKFQKTSSGVVRLQPKSAELKFVTKNDGYVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRVFIRDCSMVSVYPLVLFGGGQVNVQLQRGAFVVSLDDGWIRFVAASHQVAELVKELRCELDQLLQDKIKNPSMDLCSCPRGSRIISMIVKLITTQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B657-1", "uniprot_id": "A0ACD6B657_DANRE", "id": "A0ACD6B657-1", "name": "Putative ATP-dependent RNA helicase DHX57", "aln": "MSG--RRRSKPNRGGGR------------FNKPRGGRGGGGG------GGGKKFASGGWDDGDDFSLDFGPSRSFKPPSSRGSRGGGVRGAQGGRGRGRSLGLPRKHDDDEEKRSRFRSEQVPLPLQKIHMTSENKLQVKELLRELQNQEYQTPNSGSDYEGGEEEEDEEYDELDHREEGQYWITHDDGVEYAETDDWMED-PVEEKHKKPEPVISLFALGTLCRYGFDRERSRQALEAGEGSGCGEVGATLELLLSQMFKERFGSSALSPQTSDPPSQGECVALRQEEAFALTAIYGERFCERISNRVWTIQLDLLWLDERRIKLSDSKHSKKQSE-SNQICKFYLRGAGCKFGNRCKFKHQVHESSTSRDFCKASQPGFSNADAP---IYQLEIRFQPGSLYPFQPPLVAFSSTDESLSGAGRLSVTEYLFGQSLSAAEEGEPVVYTLISSLEEDGPVRELLSAAHHKYSAPPPVLAPPTVTPAKSRSNKNNVDNRTSATRDQSTSTSITEITNHRVKQKEVAQILSEDIDDVQDEEDDEDEEECIPVENESYVNLRKRMVKKTEIRTEQMQEENKKLCREFKRKRSSRRYISMQEQRQKLPAWQKREAILECLVKNQVLVISGMTGCGKTTQIPQFILDNFLQTGRPDRVANIICTQPRRISAIAVATRVAQERAEALGHSTGYQIRLETVRSSITRLMFCTTGVLLRRLEGDPELSGVTHVIVDEVHERTEESDFLLLVLKDLIVKRTDLKVIMMSATLNAELFSQYFNNCPCIHIPGRTFPVEQFFLEDAIAKTRYVIEDGSPYRRSTKLNRSSGPGGTTGKGRALVEDFDDDGGWSFTSFRNKESVKDSVPDQQLSQQDLTVRYSNYSKSVVKTLAAMDLDKINMDLVESLLEWIVDGDHSYPPGAVLVFLPGLAEIKQLYEQLQSNRMFNNRRTNRCVVYPLHSSLSNEEQQAVFTRPQNGVTKIIISTNIAETSVTIDDVVYVIDSGRMKEKRYDASRSMESLEDVWVSRANALQRKGRAGRVASGVCFHLFTSHRFEHHLSQQQLPEIQRVPLEQLCLRVKVLEVFAERPLDSVFSQLIEPPTEGSLEAAKQRLCALGALTDEESLTPLGWHLACLPVDVRIGKLMLLGAIFRCLDPALTIAASLAFKSPFVSPWDKREEANEKKLAFSLANSDHLALMQAYKGWCNAAQSGFKAGYQYCRENFLSIRGLQEIACLKRQFAELLSDIGFVKDGLKARVIEKMSSKGSDGVLEATGYEANLNSDNTKLMSAMLCAALYPNVVQVRSPQMKYKLTSKGAMKMQPKAEEQRFMTKSDGAVHIHPSSVNFSVRHYDSPYLVYHEKVKTSRVFIRDCSMVCVYPMVLFGGGQVNVELQRGQFIISLDDGWIKFAAASHEVAELVKELRWELDQLLEEKIKNPSMDLISCPRGSRIIHTIVSLISTQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. **:.**.:*.*: .*.:*. ***** **.:* :. *******.: . *. :* .*. *:* *.*.:::. :. :***.:******: :** ***:**:* .::**: . **** .* : : : * : :: .: . . : ** .:* :*: .*.****. *:.: .*. :* ::**:** ** * *.* **. .:: * .**: ****::**.:* **:* ***.****** *:* :* .: * . .: :*: : * : *****:* ****.:*:***:* . : : . :* :*:*:***. . **:*.***** **:*.*. * ** ::*:*:.::* *: .*****:**: ***:. : :**: ::**** ** . * .*:.:* .: .: :.. .. : ::*: : * .: :: *::: : *********:*: *: : ::.: ** *:*::*: *::**:: :: ::** ****::**:**: * *:**:********************: *: * *::***************:** ***:**** :* :.*******:*:** ***::*************. *.**:*:*********************:: :*. *:**:*****:* ***.**. ** * ****:***:*******:* ****::***** ** ::: : .: :.*: *:.::* *: :. ****::*****. ::* **.. ****:**:: **::*:*::*:*:********.*:*****:*********** ******** :*****::***::*******.*******.:* ***************:************:********.:.******.:**:*************************:::*:* :*****************:*:**:*: : *:****:***** .**.*:* ** ***** :* *****:***.************:*:***************************:****:*** *::****:***: ***** :::.. :*.*:***:**** * ***:*.*****:********.::**:*: *** ::*.****:*** *** *::*.**:**:************::*: *:: **.*.:::***: * :*:**.** *********:.***:*****:****:*************.***:**********:**** *::*******:*.****:********* ******::******:** :******** **.*::**", "identical_positions": 789, "similar_positions": 355, "identity": "54.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-408", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7F5A1-1", "uniprot_id": "F7F5A1_RAT", "id": "F7F5A1-1", "name": "E2 ubiquitin-conjugating enzyme", "aln": "SNGQRRPGGGLRPEATRGPARPRPRLLLLLFQYELGGQGRRGQPAGPRRALCPGRARADACASAPTSPTPQPGGEEARRERARAGARGSSSRPLRQAGGEHARSAAAAAAPAPPPLARSLARSPARPPARNLLTARPGGAEPSRAGRREAERAGGSRVPAPRPAERPPHRGSRSAGRRHPPAAARHCTAACDFRCSTLPGRSLGGGFFSRPPGPPPRLPPFPQGRFLGALPPPQRSGARAGRAGGREVFPRDNFTKMSSDRQRSDDESPSTSSGSSDADQRDPAAPEPEEQEERK-PS-----------ATQQKKNTKLSSKTTAKLSTSAKRIQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLTNRAEHDRIARQWTKRYAT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52483-1", "uniprot_id": "UB2E3_MOUSE", "id": "P52483-1", "name": "Ubiquitin-conjugating enzyme E2 E3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSDRQRSDDESPSTSSGSSDADQRDPAAPEPEEQEERK-PS-----------ATQQKKNTKLSSKTTAKLSTSAKRIQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLTNRAEHDRIARQWTKRYAT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969T4-1", "uniprot_id": "UB2E3_HUMAN", "id": "Q969T4-1", "name": "Ubiquitin-conjugating enzyme E2 E3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSDRQRSDDESPSTSSGSSDADQRDPAAPEPEEQEERK-PS-----------ATQQKKNTKLSSKTTAKLSTSAKRIQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLTNRAEHDRIARQWTKRYAT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S6A7-1", "uniprot_id": "B0S6A7_DANRE", "id": "B0S6A7-1", "name": "E2 ubiquitin-conjugating enzyme", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSERQRSDDESPSTSSGSSDADQRDLPVPEPEEQEERKQPTP----------PQQQKKSTKLSSKTTAKLSSSAKRIQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLTNRAEHDRIARQWTKRYAT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P52485-1", "uniprot_id": "UBCD2_DROME", "id": "P52485-1", "name": "Ubiquitin-conjugating enzyme E2-24 kDa", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSTPAAG----------SAAEVATSSATSNAPSAPSTTASNVSNTSQPTTAGTPQARGGRGSNANGGASGSNAGGGDEPRKEAKTTPRISRALGTSAKRIQKELAEITLDPPPNCSAGPKGDNLYEWVSTILGPPGSVYEGGVFFLDIHFSPEYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLQNREEHDRIARLWTKRYAT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. . .:***::.. . .: .. *: : * : : :*.:* :.: : *.:****************************:*** ******************** **.:********************************************************************* ** ******* *******", "identical_positions": 147, "similar_positions": 30, "identity": "30.95%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4089", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54001-1", "uniprot_id": "P4HA1_RAT", "id": "P54001-1", "name": "Prolyl 4-hydroxylase subunit alpha-1", "aln": "---MIWGVLMMGILLPQC-SAHPGFFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLILKDMSDGFISNLTIQR--QYFPNDEDQVGAAKALFRLQDTYNLDTNTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADYYHTELWMEQALMQLEEGEM---STVDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLVYFEYIMSKE-KDANKSASGDQS---DQKTTPKKKGIAVDYLPERQKYEMLCRGEGIKMTPRRQKRLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLSRATVHD----------------------PETGKLTTAQYRVSKSAWLSGYEDPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60715-1", "uniprot_id": "P4HA1_MOUSE", "id": "Q60715-1", "name": "Prolyl 4-hydroxylase subunit alpha-1", "aln": "---MIWVVLMMAILLPQS-LAHPGFFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLILKDMSDGFISNLTIQR--QYFPNDEDQVGAAKALFRLQDTYNLDTNTISKGNLPGVQHKSFLTAEDCFELGKVAYTEADYYHTELWMEQALTQLEEGEL---STVDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLVYFEYIMSKE-KDANKSASGDQS---DQKTAPKKKGIAVDYLPERQKYEMLCRGEGIKMTPRRQKRLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLRRATISN----------------------PVTGALETVHYRISKSAWLSGYEDPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13674-1", "uniprot_id": "P4HA1_HUMAN", "id": "P13674-1", "name": "Prolyl 4-hydroxylase subunit alpha-1", "aln": "---MIWYILIIGILLPQS-LAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQR--QYFPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADYYHTELWMEQALRQLDEGEI---STIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLKYFEYIMAKE-KDVNKSASDDQS---DQKTTPKKKGVAVDYLPERQKYEMLCRGEGIKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLRRATISN----------------------PITGDLETVHYRISKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TAB6-1", "uniprot_id": "A0AB32TAB6_DANRE", "id": "A0AB32TAB6-1", "name": "procollagen-proline 4-dioxygenase", "aln": "---MMLAWFLLSFLFHFL-YAHNDFFTSTGQMTDLLYAEKDLVTSLKEYIKQEENRLEQVKEWADKLDSLTITATQDPEGFLGHPVNAFKLMKRLNSEWSDLENLVLKDTTNGFISNLTVQR--QYFPTDEDQTGAAKALLRLQDTYQLSANAISSGDLPGVVHKSRMTVEDCYELGKIAYSDADYYHTELWMAQALSQLDEGEE---SPIDKVTVMDYLSYAIYQQGELDRALELTKRMLKLDPNHHRANGNLKYFEFQLEKQRKAENEKKEEDQKRVLDKRDAQRKR--SKDPLPERKKYERLCRGEGIKLTPRRQSRLFCRYSNNNRNPRLLLAPVKQEDEWDRPRIVRYHEIISDSEIETVKEMAKPRLRRATISNPITGVLETAPYRISKRRATVHDPITGKLTTAQYRVSKSAWLSGYEHSTIERINQRIEDVTGLEMDTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFTDVGAAVWPKKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCALSEVE-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VA69-1", "uniprot_id": "Q9VA69_DROME", "id": "Q9VA69-1", "name": "procollagen-proline 4-dioxygenase", "aln": "MAADWRLMLLLGILLLVGGPANGEVYTALAEMEELLETESVLITNLEGYIRVQEDKLNFLKNKMDEYQREHSDASHDITAYVSNPINAYLLTKRLTTDWRQVENLMEHDVGTDFLQNITQYRSLLKFPSDEDLNGAAVALLRLQDTYQLDTSSVARGKLNGIQYSTEMSSDDCFELGRQSYVNHDYYHTVLWMNEAMARMLEEPTNHTQSFTKADILEYLAFSTYKEGNIESALTMTNELLQLLPHHERANGNKRFYEKEIAQQLQLRKMKGDDGTDEMPKSDLPVAKSDPAIFDMTERRAYEMLCRGE-LKPSPSDLRSLRCRYVT-NRVPFLRLGPLKLEEVHADPYIVIYHDAMYDSEIDLIKRMARPRFRRATVQN----------------------SVTGALETANYRISKSAWLKTQEDRVIETVVQRTADMTGLDMDSAEELQVVNYGIGGHYEPHFDFARKEEQRAFEGLNLGNRIATVLFYMSDVEQGGATVFTSLHTALFPKKGTAAFWMNLHRDGQGDVRTRHAACPVLTGTKWVSNKWIHERGQEFRRPCDLEEDHGEFAI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::.:*: *: .:*: .:* :*: *. *:*.*: **: :*::*: :*: :: : *::* .::.:*:**: * ***.::* ::***: :* .*:.*:* * **.*** *** **:******:*.:.::: *.* *: :.: :: :**:***: :* : ***** *** :*: :: * ... *. :::**::: *::*::: ** :*:.:*:* *.*.***** ::* : :: : : . . . . .. . * : :.**: ** ***** :* :* * *** ** * : *.* * *: * *: :*: : *:**: :* :*:**: ***: : . ** * *.:**:******. *. .:. : * *:***::.:******.***:**:*******.**:* **. *. ****** *******. ******..: ::::******.** **. .*:** *********.*.*******:*********** *.* . ", "identical_positions": 226, "similar_positions": 169, "identity": "39.37%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-41", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TD10-1", "uniprot_id": "MIPO1_HUMAN", "id": "Q8TD10-1", "name": "Mirror-image polydactyly gene 1 protein", "aln": "--MENWSKDITH---------SYLEQETTGINKSTQPDEQLT----------MNSEKSMHRKSTELVNEIT-----------CENTEWPG-------QRSTNFQIISSYPDDESVYCTTEKYN-----------------------VMEHRHNDMHYECMTP----------------------------------CQVTSDS-------DKEKTIAFLLKELDILRTSNKKLQQKLAKEDKEQRKLKFKLELQEKETEAKIAEKTAALVEEVYFAQKERDEAVMSRLQLAIEERDEAIARAKHMEMSLKVLENINPEENDMTLQELLNRINNADTGIAIQKNGAIIVDRIYKTKECKMRITAEEMSALIEERDAALSKCKRLEQELHHVKEQNQTSANNMRHLTAENNQER--ALKAKLLSMQQARETAVQQYKKLEEEIQTLRVYYSLHKSLSQEENLKDQFNYTLSTYEEALKNRENIVSITQQQNEELATQLQQALTERANMELQLQHAREASQVANEKVQKLERLVDVLRKKVGTGTMRTVI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HM66-1", "uniprot_id": "A0AC58HM66_DANRE", "id": "A0AC58HM66-1", "name": "", "aln": "MNIRSMARDVQCALQRAKHKISSLENELSIKESCSESEEELHQLAWMHKQELKDSLVDMYKANPKVNEELKQRLPSPVKHHCSETTPQLGSTFGETTSASSQCQSISKSLEEKLLQVSKSPRSREEVLPKPPPPPPVPVPAPAEVRIMEEERRAQQKETAQQEQDINETASSPVHTPHISRTSSALLRHSHEDQGSSKVIGDSKKQVPVLDKEKNIAFLLKELDSLRELNKKLQDKLALKEKELETKLLDSQLQETEMEARANERAAVLVEEIYKAQRERDQAVMARLRLANEERDEALLRAKKLQEATLELENIKPEESDVDLEELLNRVNSAESALAIEQSGAAIIEQIQRARERRSQITSEEMKTVIQERDAALTRCKRLEQELLHIKEPSNNSANSTRHSTTQSTRERSSKLDLDLQEAQRERDKALLLSHSLQEELQTLRSVLQHQADESSPD--------SSSTFNQ-----------SQTEIQPLLYRLQQLTSEHQNAQTQLCLAQDREREANEKAQRLERLVEVLRKKVGTGSVRKVI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. ::*: * **:* : :..::.:*:* :* .*:: ..:: :*:. .*.* * . *:: * **. ::: : :.. . :**..:. : * .:* .** ****.********* ** *****:*** ::** .. :. :***.* **: *::*.****:* **:***:***:**:** ******: ***::: : ****:***.*: *:*****:*.*::.:**::.** *:::* :::* : :**:***.::*:******::******** *:** .:.***. ** *::..:** *. .* . *: *:.*: :.*:**:**** . : . *. : : **::: :* : : * :*** :*: * : ** *:: .: ****.*:*****:*********::*.**", "identical_positions": 183, "similar_positions": 149, "identity": "33.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4108", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXU8-1", "uniprot_id": "DC1L1_RAT", "id": "Q9QXU8-1", "name": "Cytoplasmic dynein 1 light intermediate chain 1", "aln": "MAAVGRVGSFGSSPPGLASTYASGPLANELASGSGGPAAGDDEDGQNLWSRILREVSTRSRSKLPTGKNVLLLGEDGAGKTSLIRRIQGIEEYKKGRGLEYLYLNVHDEDRDDQTRCNVWILDGDLYHKGLLKFSLDALSLRDTLVMLVVDMSKPWTALDSLQKWASVVREHVDKLKIPPEEMKEMEQKLIRDFQEYVEPGEDFPASPQRRATAAQEDRDDSVVLPLGADTLTHNLGLPVLVVCTKCDAISVLEKEHDYRDEHFDFIQSHIRKFCLQYGAALIYTSVKENKNIDLVYKYIVQKLYGFPYKIPAVVVEKDAVFIPAGWDNDKKIGILHENFQTLKIEDNFEDIITKPPVRKFVH--EKEIMAEDDQVFLMKLQSLLAKQPPTAAGRPVDASPRVPGGS-PRTPNRSVSSNVASVSPIPAGSKKIDPNMK-AGATSEGVLANFFNSLLSKKTGSPGGPGV-GGSPGGGAAGASTSLPPSAKKSGQKPVLSDVHAELDRITRKP--ASVSPTTPPSPTEGEAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1Q8-1", "uniprot_id": "DC1L1_MOUSE", "id": "Q8R1Q8-1", "name": "Cytoplasmic dynein 1 light intermediate chain 1", "aln": "MAAVGRVGSFGSSPPGLASTYASGPLANELASGSGGPAAGDDEDGQNLWSCILSEVSTRSRSKLPTGKNVLLLGEDGAGKTSLIRRIQGIEEYKKGRGLEYLYLNVHDEDRDDQTRCNVWILDGDLYHKGLLKFSLDALSLRDTLVMLVVDMSKPWTALDSLQKWASVVREHVDKLKIPPEEMKEMEQKLIRDFQEYVEPGEDFPASPQRRTTGAQEDRGDSVVLPLGADTLTHNLGLPVLVVCTKCDAISVLEKEHDYRDEHFDFIQSHIRKFCLQYGAALIYTSVKENKNIDLVYKYIVQKLYGFPYKIPAVVVEKDAVFIPAGWDNDKKIGILHENFQTLKVEDNFEDIITKPPVRKFVH--EKEIMAEDDQVFLMKLQSLLAKQPPTAAGRPVDASPRVPGGS-PRTPNRSVSSNVASVSPIPAGSKKIDPNMK-AGATSEGVLANFFNSLLSKKTGSPGGPGV-GGSPGGGAAGASPSLPPSAKKSGQKPVLSDVHAELDRITRKP--ASVSPTTPTSPTEGEAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6G9-1", "uniprot_id": "DC1L1_HUMAN", "id": "Q9Y6G9-1", "name": "Cytoplasmic dynein 1 light intermediate chain 1", "aln": "MAAVGRVGSFGSSPPGLSSTYTGGPLGNEIASGNGGAAAGDDEDGQNLWSCILSEVSTRSRSKLPAGKNVLLLGEDGAGKTSLIRKIQGIEEYKKGRGLEYLYLNVHDEDRDDQTRCNVWILDGDLYHKGLLKFSLDAVSLKDTLVMLVVDMSKPWTALDSLQKWASVVREHVDKLKIPPEEMKQMEQKLIRDFQEYVEPGEDFPASPQRRNTASQEDKDDSVVLPLGADTLTHNLGIPVLVVCTKCDAISVLEKEHDYRDEHFDFIQSHIRKFCLQYGAALIYTSVKENKNIDLVYKYIVQKLYGFPYKIPAVVVEKDAVFIPAGWDNDKKIGILHENFQTLKAEDNFEDIITKPPVRKFVH--EKEIMAEDDQVFLMKLQSLLAKQPPTAAGRPVDASPRVPGGS-PRTPNRSVSSNVASVSPIPAGSKKIDPNMK-AGATSEGVLANFFNSLLSKKTGSPGGPGVSGGSPAGGAGGGSSGLPPSTKKSGQKPVL-DVHAELDRITRKP--VTVSPTTPTSPTEGEAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LUM9-1", "uniprot_id": "Q1LUM9_DANRE", "id": "Q1LUM9-1", "name": "Dynein light intermediate chain", "aln": "MATTGRN--------TLLSVSTN---VNNSTSESQNP---EEEDGQNLWSSILSEVSTRSRSKLPSGKNVVVMGEVGSGKTTLVAKLQGVEEYMKGRGLEYLYFNVHDDDIDDQSRCNAWVLDGDLYHKGLQKFAISLENLEDSLILFVVDLSRPWLALDSLQKWGSVVRDFVDKLRVPPETMRELEHRLTKQFQEYVEPGSDLDAVPQRRNPESDE---ESVLLPLGENTLTHNLGLPIVVVCTKCDAISTLEKEHDYKDEHLDFIQSHIRRFCLQYGAALLYTSMKENKNLDLLYKYLVHRLYGFPFNSPAQVVEKDSVFIPSGWDNEKKIAILHENFQMVKAEDSFEDVIVKPPVRKFVH--EKEVQAEDDQVFLVKLQSLLSKQPPVTAGRPVDPTNRAPTGS-PRTTNRSAAANVANVMPMQSGTKKIDPNMK-GGQTSEGVLANFFNSLLTKKAGSPG--------PGGQPAGGGSNTPGTVRKSGSKLGLTDVQAELDRISNKSDLDSSAPNATTPPAENDKS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZ20-1", "uniprot_id": "Q9VZ20_DROME", "id": "Q9VZ20-1", "name": "Dynein light intermediate chain", "aln": "------------------MAMNSGTQTNALTSSFTMKKKDAAAEKENLWSAILNEVQTQGSTKLPSNKSVLVLGDNATGKTTLIAKLQGVEDPKKGSGLEYAYIDVKDEYRDDMTRLGVWVLDGDPGHTNLLHYALNETNYAHTLVILTVSMTQPWGWLEQLNHWIKVLGQHIDSLQLDAKEKEAARQRLTTTWQSYCEVGDDLDPGSPVKRTMRNNSIDEDDLLPLTEDALITNLGLDIVVVVTKTDYMTTLEKEYEYRDEHFDFIQQWIRNFCLRHGTSLFYTSVKEDKNCDVLYKYLTHRIYGLPFRTPALVVEKDAVLIPAGWDSLKKISILYENMHGVKAENPYTDIIKSPPTRKAVSNREAEVQTEDEQAFLARQQEILKQGDQVRGESPLRSQGVGSNKSGPRTPGTTGQS----------SPKKIDPKLTPATPGAEGVLANFFNSLLHKKSGSPGTGGP-GGAGNPAGPGRTANGTDAVMTPEKLAVRTDAAAELDRLSR-----SVKKEIDMSQSEC---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * :* : :**** ** **.*:. :***:.*.*:::*: .:***:*: ::**:*: ** **** *::*:*: ** :* ..*:**** *..* ::::. . .:*:::.*.:::** *:.*::* .*: :.:*.*:: .: . .::* :*.* * *.*: . . : . :: :. :*** ::* ***: ::** ** * ::.****::*:***:****. **.***::*::*:***:**:** *::***:.:::**:*:. ** *****:*:**:***. ***.**:**:: :* *: : *:* .**.** * * *: :**:*.** : *.:* : . . *: . . * ***.. : : ..*****::. . :************ **:**** * .. . :. .. . *. *****::. : . :* ", "identical_positions": 178, "similar_positions": 166, "identity": "33.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4120", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UG20-1", "uniprot_id": "KMT2E_MOUSE", "id": "Q3UG20-1", "name": "Histone reader KMT2E", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSIAIPLGVDTTETSYLEMAAGSEPESVEASPVVVEKSNSFPHQLYTS---------------SSHHSHSYIGLPYADHNYGARPPPTPPASPP--------------------------------------------PSGLISKNE----------VGIFTTPNFDETSSATTISTSEDGSYGTDVTRCICGFTHD-DGYMICCDKCSVWQHIDCMGIDRQ-HIPDTYLCERCQPRSLDKERAVLLQRRKRE---------------------------------------NMSDGDTSATESGDEVPVELYTAFQHTPTSITLTASRVP-KVTDKRRKKSGEKEQ-NFSKCKKAFREGSRKSSRVKGSAPEIDPSSDSSNFVWETKIKAWMDRYEEANNNQYSEGVQREAQRLAQRLGSGNDSKDMNKSELSTNNSLFRPPVESHIQKN---------KKILKSAKDLPPDALIIEYRGKFMLREQFEANG-----------------YFFKRPYPFVLFYSK--------------------------FHGLEMCVDARTFGNEARFIRRSCTPNAEVRHEIEEGTIHLYIYSIQSIPKGTEITIAFD------------------FDYGNCKYKVDCACLKENPECPVLKRSSESTEN-------------------------------INSGYETRRKKGKKEKDTSKEKDIQNQNMTLDCE-------------------------------------------------------------------GTNNKIRSPETKQR-----------------------------------KLSPLRLSVSNNQEPDFIDDMEEKTPISNEVEMESEE------QIAERKRKM------------------------TREERKMEAILQAFARLEKREKRREQALER---------------------ISTA-----KTEVKPECKESQVIADAEVVQ---EQVKEETAIKPAAAKVNRTKQRKSFSRSRTHIGQQR-------------------------------RRHRTVSMCSDIPPSSPDIEVLSQQNEIENTVLAIEPETETAVAEIIPEAEVPALNKCPT-----KYPKTKKHLVNEWLSEKNEK--TGKPSDSLSERPLRITTDPEVLATQLNSLPGLTYSPHVYSTPKHYIRFTSPFLSEK-----------KRRKETTEN--ISGSCKKRWLKQALEEENSTILHR---YHSPCQERSRSPTVNGENKSP------------------LLLSDSCSLPDLTTPLK-----------------------------------KRRLYQLLDTAYSESSTPTPSPYATPTHTDITPTD---PAFATPPR-----------------------------------IKSDDETYRNGYKPIYSPVTPVTPGTPGNTMHFENISSPESSPEIKRCTYNQEGYDRPSNMLTLGPFRNSNLTELGLQEI--------KTIGYTSPR-SRTEVNRPCPGEKESVSDLQLGLDAVEPAALQKSMETPAHDRTEPSNQLDS--THSGRGTMYSSWVKSPDRTGVNFS-VNSNLRDLTPSHQLETGGGFRVSESKCLIQQDDTRGMFLGAAVFCTS----EDGLASGFGRTVNDNLIDGSCTPQNPPQKKKVSLLEYRKR-----QREARKSGSKPENFALISVSPHPSGSLSSSGDGCVHSSENGEQAENQASLPLPPPAAAA------------------AATAAAAYSASSEEGSSNCPVKDANSSEKKDPEVQWTASTSVEQVRERSYQRALLLSDHRKDKDSGGESPCVSCSPSHVQSPPSSHSNHIPQVHAQSLAPSLSELMADPDAEGTEATSTSECPSPDTSQ----SPSKTSKPGSPGPINPAQSHGKILTKPDSHWEATATVSEADNSVHQNPEPQHRQLSSN-----TPALSQNHAPQAHALSANDQLPQKLPSAPTKLHCPPSPHTENPPKSSTPHTPVQHGYLSPKPPSQHLGSPFRPHHSQSPQVGTPQRETQRNFYAAAQNLQANPQQATSGALFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSS-YYQNQQPSANFQ---NYNQLKGSLSQQTVFTSGPNQALPGSTSQQSVPGHHVTPGHFLPSQNPTIHHQPAAAAVVPPPPPPPPAPGPHLIQQPSSHQQHSVAHGVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPTTGLQSLQAQHQHVVNSAPPPPPPPPPPPPASVLVSGHHSASGQALHHPPHQGPPLFPASAHPAVPPYP--SQATHHTTLGPG-----------PQHQPSGTGPHCPLPVAGPHLQPQGPNSIPTPTASG--------------FCPHPHPGSVALPHGVQGPQQASPVPAQIPIHRAQVPPTFQNNYHGSGWH-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ASP1-1", "uniprot_id": "A0A8I6ASP1_RAT", "id": "A0A8I6ASP1-1", "name": "Inactive histone-lysine N-methyltransferase 2E", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSIAIPLGVDTTETSYLEMAAGSEPESVEASPVVVEKSNSYPHQLYTS---------------SSHHSHSYIGLPYADHNYGARPPPTPPASPP--------------------------------------------PSGLISKNE----------VGIFTTPHFDETSSATTISTSEDGSYGTDVTRCICGFTHD-DGYMICCDKCSVWQHIDCMGIDRQ-HIPDTYLCERCQPRSLDKERAVLLQRRKRE---------------------------------------NMSDGDTSATESGDEVPVELYTAFQHTPTSITLAASRAP-KVTDKRRKKSGEKEQ-NFPKCKKAFREGSRKSSRVKGSAPEIDPSSDGSNFVWETKIKAWMDRYEEANNNQYSEGVQREAQRLAQRLGSGSDSKDMSKPELSVNSSLFRPPVESHIQKN---------KKILKSAKDLPPDALIIEYRGKFMLREQFEANG-----------------YFFKRPYPFVLFYSK--------------------------FHGLEMCVDARTFGNEARFIRRSCTPNAEVRHEIEEGTIHLYIYSTQSIPKGTEITIAFD------------------FDYGNCKYKVDCACLKENPECPVLKRSSESTEN-------------------------------INSGYETRRKKGKKEKDISKEKDIQNQNITLDCE-------------------------------------------------------------------GTNNKIRSPETKQR-----------------------------------KLSPLRLSVSNNQEPDFIDDMEEKTPISTEVEMESEE------QIAERRRKM------------------------TREERKMEAILQAFARLEKREKRREQALER---------------------ISTA-----KTEVRPECKESQVISDADVVQ---EQVKEETAIKPTAAKVNRTKQRKSFSRSRTHIGQQR-------------------------------RRHRTVSMCSDIQPSSPDVEVMSQQNDIENTVLAIEPETEAAVAEIITEVEAPALNKCPT-----KYPKTKKHLVNEWLSEKNEK--TGKPSDSLSERPLRITTDPEVLATQLNSLPGLTYSPHVYSTPKHYIRFTSPFLSEK-----------KRRKETTEN--ISGSCKKRWLKQALEEENSTVLHR---YHSPCQERPRSPTVNGESKSP------------------LLLSDSCSLPDLTTPLK-----------------------------------KRRLYQLLDSAYSESSTPTPSPYATPTHTDITPTD---PAFATPPR-----------------------------------IKSDDETYRNSYKPIYSPVTPVTPGTPGNTMHFENISSPESSPEIKRCTYNQEGYDRPSTMLTLGPFRNSNLNELGLQEI--------KTIGYTSPR-SRTEVNRPCPGEKESVSDLQLGLDAVEPAALQKTMETPAHDRTEPSSQLDS--THSGRGTMYSSWVKSPDRTGVNFS-VNSNLRDLTPSHQLEIGGGFRISESKCLT-QDDARGMFMETAVFCPS----EDGLVSGFGRTVNDSLIDGSCTPQNPPQKKKVSLLEYRKR-----QREARKSGSKPENLALISVSPHPSGTLSSSGDGCVHSSENGEQPENRASLPLAPP--------------------------AAACTASCEEGSSDCPVRDANPTEKTDPEVQWTASTSVEQVRERSYQRALLLSDHRKDKDGGGESPCVSCSPSHVQSSPSSHSNHIPQVPAQSLAPPLTEPMADLDPEGTEATSTSECPSPDTSQ----SPSKTSKPGSPGPINPAQSHGKMLTKPDSHWEATATVSEAESSVHLKPELQQKQLSSN-----TPALSKNHPPQAHVRNANDQLPQKLPSAPTKLHCPPSPHTENPPQSSTPHTPVQHGYLSPKPPSQHLGSPFRPHHSQSPQVGTPQRETPRSLYPAAQNLQANAQQAPCGALFTQTPSGQSSAAYSPFNQQALSSPAPPPPPPPPPSA-YYQNQQPSANFQ---NYNQLKGSLSQQTVFTSGPNQALPGTTSQPSVPGHHVTPGHFLPSQNPTIHHQ-TAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGTVHAVTPGSHIHSQTVGHHLPPPPPPPGPAPHHHPPPHPSTGLQSLQAQHQHVVNSAPPPPPPPPPP--ASVLVSGHHSASGQALHHPPHQGPPLFPVSVHPAVPPYP--SQATHHTTLGPG-----------PQHQPSGTGPHCPLPVPGPHLQPQGPNSIPTPTASG--------------FCPHPHPGSVALPHGVQGPQQASPVPGQIPIHRAQVPPTFQNNYHGSGWH-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IZD2-1", "uniprot_id": "KMT2E_HUMAN", "id": "Q8IZD2-1", "name": "Histone reader KMT2E", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSIVIPLGVDTAETSYLEMAAGSEPESVEASPVVVEKSNSYPHQLYTS---------------SSHHSHSYIGLPYADHNYGARPPPTPPASPP--------------------------------------------PSVLISKNE----------VGIFTTPNFDETSSATTISTSEDGSYGTDVTRCICGFTHD-DGYMICCDKCSVWQHIDCMGIDRQ-HIPDTYLCERCQPRNLDKERAVLLQRRKRE---------------------------------------NMSDGDTSATESGDEVPVELYTAFQHTPTSITLTASRVS-KVNDKRRKKSGEKEQ-HISKCKKAFREGSRKSSRVKGSAPEIDPSSDGSNFGWETKIKAWMDRYEEANNNQYSEGVQREAQRIALRLGNGNDKKEMNKSDLNTNNLLFKPPVESHIQKN---------KKILKSAKDLPPDALIIEYRGKFMLREQFEANG-----------------YFFKRPYPFVLFYSK--------------------------FHGLEMCVDARTFGNEARFIRRSCTPNAEVRHEIQDGTIHLYIYSIHSIPKGTEITIAFD------------------FDYGNCKYKVDCACLKENPECPVLKRSSESMEN-------------------------------INSGYETRRKKGKKDKDISKEKDTQNQNITLDCE-------------------------------------------------------------------GTTNKMKSPETKQR-----------------------------------KLSPLRLSVSNNQEPDFIDDIEEKTPISNEVEMESEE------QIAERKRKM------------------------TREERKMEAILQAFARLEKREKRREQALER---------------------ISTA-----KTEVKTECKDTQIVSDAEVIQ---EQAKEENASKPTPAKVNRTKQRKSFSRSRTHIGQQR-------------------------------RRHRTVSMCSDIQPSSPDIEVTSQQNDIENTVLTIEPETETALAEIITETEVPALNKCPT-----KYPKTKKHLVNEWLSEKNEK--TGKPSDGLSERPLRITTDPEVLATQLNSLPGLTYSPHVYSTPKHYIRFTSPFLSEK-----------RRRKEPTEN--ISGSCKKRWLKQALEEENSAILHR---FNSPCQERSRSPAVNGENKSP------------------LLLNDSCSLPDLTTPLK-----------------------------------KRRFYQLLDSVYSETSTPTPSPYATPTHTDITPMD---PSFATPPR-----------------------------------IKSDDETCRNGYKPIYSPVTPVTPGTPGNTMHFENISSPESSPEIKRRTYSQEGYDRSSTMLTLGPFRNSNLTELGLQEI--------KTIGYTSPR-SRTEVNRQCPGEKEPVSDLQLGLDAVEPTALHKTLETPAHDRAEPNSQLDS--THSGRGTMYSSWVKSPDRTGVNFS-VNSNLRDLTPSHQLEVGGGFRISESKCLM-QDDTRGMFMETTVFCTS----EDGLVSGFGRTVNDNLIDGNCTPQNPPQKKKVSLLEYRKR-----QREARKSGSKTENFPLISVSPHASGSLSNNGDGCASSNDNGEQVDHTASLPLPTP--------------------------ATVYNATSEETSNNCPVKDATASEKNEPEVQWTASTSVEQVRERSYQRALLLSDHRKDKDSGGESPCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDPENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEAENGVHLKTELQQKQLSNN-----NQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPSANFQ---NYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQ-TAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPS---SVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYP--SQATHHTTLGPG-----------PQHQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTASG--------------FCPHP--GSVALPHGVQGPQQASPVPGQIPIHRAQVPPTFQNNYHGSGWH-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q6C7-1", "uniprot_id": "A0A8M9Q6C7_DANRE", "id": "A0A8M9Q6C7-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSIVIPVGVDTANTSYLDMAAGSEPESVEASSVVVEKS-TYPHQIYSS---------------SSHHSHGYIGLPYADHNYGARPPPTPPASPP--------------------------------------------PSVLIRPGESLFVSGSRPGENLFVPGGQDEASRGTTLSTSEDGSYGADITRCICGFTHD-DGYMICCDKCSVWQHIDCMGIDRQ-HIPETYLCERCQPRTLDREHAILLQTRKRE---------------------------------------NMSDGDTSATESGDEVPLELYTAFQHTPTSITLTTARLGNKQADKKRKKSGEKEPPATARAKKSFREGSRKSSRVKGSAPECEPIDPPS--LWENKMKSWMERYEEASSNQYSEEVR-----LLLRVKEARDGKTLAYN---THTAAFKPPVESQVQKN---------KRILKAVRDLAADSLIIEYRGKVMLRQQFEANG-----------------YFFKRPYPFVLFYSK--------------------------FDGLEMCVDARSFGNEARFIRRSCTPNAEVRHVIEEGMLHLYIYSLRSISKGSEITIGFD------------------YDYGSCKYKVDCACVKGNPECPVLKHNLEPTEN-------------------------------LGS---STRRRGRKDKEPSRDESGQNQNLTMDCD-------------------------------------------------------------------GSKGKTLN-DAKQR-----------------------------------KLSPLRLSISNNQDPELIEDLEEKTSVSNEVEMESEE------QIAERRRKMGSPAEESHRHDAGASCCRALRNKETREERKMEAILQAFARMEKREKRREQALER---------------------IGTKGEVGGRSDIKEEAPATPEAESPAVIQPLLEVVKEEPGLKP--AKVSRNKQRKSFSRNRTHIGQQR-------------------------------RRARTVSTCSDLPPSSPGDTLEPLMAETQDIEMPVAPEADAPPTQPPETSPPHSGSPAPTCRSGQKYPKTKKHLVSEWMGVDKQERVASRTPEPPPERPLRISSDPEVLATQLNSLPGMSCSSHVYSTPKHYVRFSSPFLANRSPSTPGVPTGRRRSREMPETPTSTGSCKKRWLKQALEEEGSTSPGGGRPFLLIPSESPLSPSINGESCSP------------------LPLNGSCSLPELPTPLK-----------------------------------KRRLCS-LDPCMSETSTPYGSPCATPTRTESTEAPGTPSLLATPPR-----------------------------------PRPEE--------PSTEPSTPLQ--MPNHPLLQESESSMDSSPDGSRRPSTQD-VERPPSLLASPSVRNVSSDTAPQESS--------KSMGSLSPQPSHTEPQDAAVDEG----------MEVDAAAAVTSAAGGGGGSEASTSAPET--PVSS----YPPWMKSPERGGISFSPVNSNLRDLTPSHTLEMG-AYRP--------DSTSSGPFSEAAPFFSCN---EESSGVTFTRSLSGDGTGEGSTAKNP-QKKKVSLLEYRKR-----QREARRSGSKGECSSPVSTAP-PVDVFPVAVEMAVDPPAPAATPTPRTPQPSEDP--------------------------------------------DAPQGER-DGEGQWTSSTSVEQARERGYHRALLLSDHRKDTD-GGES------------------------------------------EGGD-SQVKDCSSPKSCK-------------SPSTHAPCSPAAQAVSRPSKDEDEAQTRGPAQPQAVSVQPSSAKTPSSK-----PAALT-----------------------PSKLHCGPS----GASQSHYAGPSLMH---SPKAQPQ--GSPFR---------------GQRAFLTAQPQNQPQPQ-ATSG-----------PATFPQYNPQNAPPPPPPPPPAPPTSAPYFPTQPTAA----------------------AAPFPAFKPTVASPFPPGSQP-----LLQTHHALHYQ-SSAAPPPPPPPPPPHPQPGPTLLHVNLQPPSLQQHQLLLSSAPP-------------PPPPPPPQTQSSQQPPPNSGTLLS---------IKQGPHPPLPPPPP-----------APSTNAPPHPFQNISGFQTTLLHQSAPANPSVTASTYQQTVLPP-----------PPPPPPQQTPPTQTPPNPSIPQIAGGNRGPAPSSAS--------------FHTTG--------------------------------------YLGTGWH-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUB5-1", "uniprot_id": "UPSET_DROME", "id": "Q9VUB5-1", "name": "Histone reader upSET", "aln": "MPMSSHDSVFVEPAVSSSGGGSTSSINRIGVASGPQPPPPHIVIDGSSLSTQAQLRIMQRRMSISTRQILSASQSQSINQSQKYAVRTAAGTGALAAGAASSGSSGQELINPQIYKIVTTDGSTSNVIIDASAAAPPHNSKLLLSNLTVLSKQAPVQGAAGQQQQQLNYLGAKSLPYVSASPAKTQQQPQKFGSISAFKAQHQQQQQHPHATLQKVTLGSRVATRLQSYVPASPSQIMVQPAQPKYVNATATTIGGNAALLKKANQKITVKSVSNMSQQQQQQQQQQQQQLLQAQQLKTFITQQQQQQTYKAGAKAKFVKQTTALSIAALPQQQQQTTYAKQSMVTTSTPAKVTKLNSKYVQQQISLPQGTQLQHKASPNVTGGGYLLQQSQAAVGGTIKFVNSHGTVIQQHPQQQQATKRTHYNSSGSSDNEQHAVANSSLITDDVMIVNGTQMTDELSARILQSMAQKSFSQQQRFHQVPATGSGNMPPPTQIIYSNSTSNGAAASSPGGNASGNMLLAHYQAAGTKPVSSASFITVTGTPPVTVATTPSVSISSHGFASGSAAISSYMSSATAARRQSVSAPSSRAVSLERKQHHQQLQHDVIGGGRKAPTVIEYYNKHGVNSIVGSSNNLAQSNSMSNLAGPRSNSGSGFATTTPTPATPLHLTPVNVPVHVEAAPPSSPALVKGSSQPPAQPQQQQQQAHPLGPNQLNANDEELYIEEVRPVPVLTQDLRLQQLHAIMQDHTYASQQQQQQPQQAAGDTTNPGAAQQVQQPQQWSLGGIGVTVSGSQGTPTAVGGYCSYFGQQIARSQADDDAHSAISSSSRMGLASTDIDPGEETETAPEAEAEDDSVTRCICELTHD-DGYMICCDKCSAWQHVDCMGIDRQ-NIPEEYMCELCQPRAVDKARARALQRQKRKEHMLLVATQAANGAAAVAAGTTLSGGLGSGLPMSEELQHRLASGLNGGFATGTGMSKKSKKTKENSGSTSTLKKTKKSAVGMGGEKNASGSGTPTGSSGKTSKKSSKRKSKSGGDGSSGGGSSPALTAAEKHAANLRQWIENYEYAVTNHYSPELRARLHAIQKQPSLLQSIQNTENKALRQIQQQLSTAGSAEQLEQRAQLIPYAGAKVLISSVDLSPHAPIHELRGKYMLTTQFRTQNPTVNMNTPPPSNYLNSFKAHKTPGQFVFFYQLPGVEAPMQTLRPDGSVPQVAQQPPSYLKGPEVCVDTRTYGNDARFVRRSCRPNAELQHYFEKGTLHLYIVALTHIRAQTEITIRHEPHDLTAVEQKKSHAAVIQPTSTRCACDMGSDCLFALPLAVQQQLQAPPTQPRSSHRNKAAAAAAAAAAANSAAAIQLTMGLGVGATVAAGASVLPNSRNRSTSSSGESSQMGLNSPQLGQLNLGFKTSVTATSLTAPVPGVHCNNSGGSSSSSNNSCSVSMSSVLHDSGICTSSSSPSVSIPSPTPTQMQSPTLQQHPQQIPQQQLSLLQRSPTQQHQQQILAALPTPMLTPMLSPQLPKPAQQQAHVVLPQSQQTSLLQQQQSQQSQEPLAVIAAAAAAQQPMATYFVRQPQQQQQQQSPKPQALVAQQQHVVGAQQQQHFLQQQQKQQQQQMADEARMAVSALQTLHAAPTSHIVSPIKVAAVQQQSQPQQQQQNTHQQPHNQQAVQQQSNQLQQQQSQQPNYPQSPQRQQKPQPVQHQPQIVISTGAQAIPATMPTKLSSPTKSAAPVISNNNITVSAQSSVVGGKKTPAKHPQQQQQQQQQPVTPVSAATAPAATPSSSESKEDDVSASSTTTPTTR-TPAKDKPKQSREDRKLEAILRAIEKMEKQEARGKKDTRQSSGGKRQASNSPASPNKRNSSNSISEDVETPTSTNSAAAAAQRRNKKKRKVSRSLNNNTNGLGSGGGSNNKRRKSIVVESDGESHALTNSESEDQGQHPQSHHSGSEDQAAGLLLALAHNNSSPNEPFKSPLSQSHSLPATPASVSSACLLIEAAMGPLQQQPAPASASPSLAEFKYPPGGAKTKKSLMSSWFQQAEQQHASGLDSLVQAAMSEINGEREQLQRQPQGESLPAPALLKVEQFIHQAESTTAVPAREQLHLPLQNNSSVKKRWLRQAISEETTPVDELQQSQNQSVTATPSPQPVPTVSPLANGFSTPLKKRRLVVVSNGTNVESDETHIDVIGEPKDEAEENVAMTELKVEIENHHQEQDDDVDILRSPSPGTHQIVAEDNLVKIEPEDTSAAADDVKIDVEREESQACDKFEEMVKVKREEEEQREKEIKQLQERQEHEQPKVEPAPVEPKLENTVAKAEPKVEPSQEIVSKKEPTKVEPKPGESLLRSTATVTATPTAATIAATTLLDVSKVAFKTRPPLKLEDEPQKKKPKLESILPAPVATVPPVSVPPIPAASNATTSAVTNTAAASLTTTTAPSSTKNLTEHDIQERLLSFHAANISYLQSRNKKATAALTSASPSQKSNSSSGGSGTESKKSSKDKDEKRDKEKQLKKSKKEKKKSKDKEKQKAAVNVNSTSQIVDTKKKTTQPSKPDSKSSIAPVLVPPSLPVATANGKTKHTAYNNVDQQQQQQMRRRTMSMCITPVTPTPVVTPSPLHGTPPSTKKRQTNFEQELTKPNSQILSSSILLNSSKGLGLPLAAPTVVSVPTAVQQQQHRKENNHQEATPASGGPMSLAAAIASGKLNAISRRRESMCGSRQQQALIAAALKKEKKEKKKSKKKDREKQKHDKQKGKEKEREKDKEKDNKQKTNHIQKPAHPTTVPANSMPISAPAPVPVLVPTPVTTPKAAPIPVLITQPTPSPIHVTQPLVNNCSTKVASLPFYNTIYGKLQDPSTPTSSPIPVTNTMPSLAEYLESTKSKTTALSAVKPIGIAAVTPLSSAITPAKVAPSSLEMPPPATTPLKLYTRTASHDPRLNPMLTVPDPTPMPKRKLSISEYRMRHRPSVDTAPTTPTTPTTP-TTPTTPPGSNKDRSFAKPQTINKCSLQSPERFQAAIRERRNSISAHHPQQNAHHNLNNNKGGISNKSGSSSGNHLQQALGVAGGRLQSKNAIVDPAATTLSTVNSILSTAQKLHMFDDKPKGGHFNAAPTLLEQQQEKMSERSRCLQRTISCDSRVIERLGTGAAAGALEKVTTASTRRDAV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36124-1", "uniprot_id": "SET3_YEAST", "id": "P36124-1", "name": "Histone reader SET3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVPNSKEQSLLDDASTLLLFSKGKKRAEEASKIGSKTDTIEHDESHER--------------EKKGAIEMAAAALATASTVSLPLKKATEQS----------------------------------------------AAEAATST----------AAKEETENQPQKQPQWPVPDSYIVDPDAGIITCICDLNDD-DGFTIQCDHCNRWQHAICYGIKDIGMAPDDYLCNSCDPREVDINLARKIQQERIN-------------------------------------VKTVEPSSSNNSASNKNNGRDRASSTTISDVGDSFSTDQDNTNHRDKRRKRNPSNNSIDSKNESASVNSSDGLTSMPKKKEHFLSAKDAYGAIYLPLKDNVFKSDLIEPFLNKHMDDNWVIQYPHKTFKSVSIEVKPYADIAYSRTYPGFT-------------------KLGVYLKKDCIKGDFIQEILGELDFYKNYLTDPR-------------NHYRIWGTAKRRVIFHSH-----------------------------WPIYIDARLSGNSTRYLRRSCQP-----------NVELVTIKLQDTDNRNDKSSGRK--------------------SSRIKFVLRALRDISEDEELYIKWQWDSKHP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILKLIKGMTIDSLDDLERYGLINSVETILSNG-----------------------------------------ECGCGNNSKDCYLLKVKRYAQS-----------------------------------LYKSVKSRGKMNNRYKLNEILN------QYNCKKRREPPILHRLEEKAQNTIERAPILLNN--------------------------------FYRQKFLNRNNGPKIPQKNTIDSTNNPDDIAKPFKFALFAQHSSNIS----------------------------------------VPKKNETSEKPLIITKSTDYDESHITNIEELPIP----------------------------------------------------------------------VLLPINKTSRQTANDVEESQS---------------------KNEHKLSRTPSLSN----------------------------------------------FNKELSKEAQHSQAKTKEIMTEAS----------------------------------------------------------------VNSRRESTPESIMHLSDFSSSQ---------------LHSKKKLSFADYRKKLLK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P42948-1", "uniprot_id": "SET4_YEAST", "id": "P42948-1", "name": "Histone reader SET4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSPESLSSRHIRQGRTYTTTDKVISRSSSYSSNSSMSKDYGDHTPLSVSSAASETLPSPQYMPIRTFN-----TMPTAGPTPLHLFQNDRGIFNHHSSSGSSKTASTNKRG----------------------------------------IAAAVALATAATIPFPLKKQNQDDNSKVSVTHNESSKENKITPSMRAEDNKPKNGCICGSSDSKDELFIQCNKCKTWQHKLCYAFKKSDPIKRDFVCKRCDSDTKVQVNQVKPMIFPRK------------------------------------------------MGDERLFQFSSIVTTSASNTNQHQQSVNNIEEQPKKRQLHYTAPTTENSNSIRKKLRQEKLVVSSHFLKPLLNEVSSSNDTEFKAITISEYKDKYVKMFIDNHYDDDWVVCSNWESSRSADIEVRKSSNER----------------------------DFGVFAADSCVKGELIQEYLGKIDFQKNYQTDPN-------------NDYRLMGTTKPKVLFHPH-----------------------------WPLYIDSRETGGLTRYIRRSCEPN----------------VELVTVRPLDEKPRGDN--------------------DCRVKFVLRAIRDIRKGEEISVEWQWDLRNP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IWEIINASKDLDSLPDPDKFWLMGSIKTILTNC-----------------------------------------DCACGYLGHNCPITKIKN-----------------------------------------FSEEFMRNTKESLSNKSYFN----------------TIMHNCKP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : . . : . . . . . . . *** ... * * *::*. *** * .:. ::*: *:. : . : : . .: . * . . . : . ::: . : : . * * *: : :: :: . *:*: : :*:* *. :*::**** * : . . : . : . . : : :. : :: : : :. . .: . . : ", "identical_positions": 28, "similar_positions": 89, "identity": "0.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4135", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P14316-1", "uniprot_id": "IRF2_HUMAN", "id": "P14316-1", "name": "Interferon regulatory factor 2", "aln": "-----MPVERMRMRPWLEEQINSNTIPGLKWLNKEKKIFQIPWMHAARHGWDVEKDAPLFRNWAIHTGKHQPGVDKPDPKTWKANFRCAMNSLPDIEEVKDKSIKKGNNAFRVYRMLPLSERPSKKGKKPKTEKEDKVKHIKQEPVESSLGLSNGVSDLSPEYAVLTSTIKNEVDSTVNIIVVGQSHLDSNIENQEIVTNPPDICQVVEVTTESDEQPVSMSELYPLQISPVSSYAESETTDSVPSDEESAEGRPHWRKRNIEGKQYLSNMGTRGSYLLPGMASFVTSNKPDLQVT-IKEESNPVPYN-----SSWPPFQDLPLSSSMTPASSSSRPDRET-RASVIKKTSDITQARVKSC--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23906-1", "uniprot_id": "IRF2_MOUSE", "id": "P23906-1", "name": "Interferon regulatory factor 2", "aln": "-----MPVERMRMRPWLEEQINSNTIPGLKWLNKEKKIFQIPWMHAARHGWDVEKDAPLFRNWAIHTGKHQPGIDKPDPKTWKANFRCAMNSLPDIEEVKDRSIKKGNNAFRVYRMLPLSERPSKKGKKPKTEKEERVKHIKQEPVESSLGLSNGVSGFSPEYAVLTSAIKNEVDSTVNIIVVGQSHLDSNIEDQEIVTNPPDICQVVEVTTESDDQPVSMSELYPLQISPVSSYAESETTDSVASDEENAEGRPHWRKRSIEGKQYLSNMGTRNTYLLPSMATFVTSNKPDLQVT-IKEDSCPMPYN-----SSWPPFTDLPLPAPVTPTPSSSRPDRET-RASVIKKTSDITQARVKSC--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58GMF7-1", "uniprot_id": "A0AC58GMF7_DANRE", "id": "A0AC58GMF7-1", "name": "Interferon regulatory factor", "aln": "MTSIKMPVDRMRMRPWLEEQINSGQIKGLHWVNEEKKIFQIPWMHAARHGWDLEKDAPLFMKWAIHTGKYCPGIDKPDPKTWKANFRCAMNSLPDIEEVKDKSMKKGSNAFRMYRMLSSSEKAVRKGRK-KLDPEQKAKRVFQKRKAGTPRKYKMLKELSEE------ELREDITPDSTVLLAEQ---ENCPEREAAVGEPPDVCAVVEVATETEEQAT-----RPLQDSHVSSYSESD-TESTYSEEDLVQLPQDLSLKSSQKSSCASVLRIP-PSAQSSPNTLFTSVKTNFKITSSREDSPLVAYNTPPWFSCLFNFRNVTDGEPSSPALTPDLTSSTTSQASATSKAVDLSVAKHDTTLQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:**************. * **:*:*:******************:******* :*******: **:***************************:*:***.****:****. **:. :**:* * : *::.*:: *: .: : :. :* * ::::: . .:::. * :. * : * :***:* ****:**:::*.. *** * ****:**: *:*. *:*: .: . :. : .. * : . .. ::.** *.::::* :*:* :.** *. * ::. . :*: :.. .. * :**. .*: *:: *: .: ", "identical_positions": 152, "similar_positions": 104, "identity": "41.87%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4145", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7KZI7-1", "uniprot_id": "MARK2_HUMAN", "id": "Q7KZI7-1", "name": "Serine/threonine-protein kinase MARK2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQ-------------------------PHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQ-IMKDRWMNVGHEDDELKPYVEPLPDYKDPRRT------------ELMVSMGYTREEIQDSLVGQRYNEVMATYLLLGYKSSELEGD------TITLK----PRPSADLTNSSAPSPSHK-VQRSVSANPKQRRFSDQAAGPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAVSAARPRQHQKSMSASVHPNKASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPS---GHSQGRRGASGSIFSKFTSKFVRRNLSFRFARRNLNEPESKD-----RVETLRPHVVGSGGN--DKEKEEFR----------------EAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIASKIANELKL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q05512-1", "uniprot_id": "MARK2_MOUSE", "id": "Q05512-1", "name": "Serine/threonine-protein kinase MARK2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMLRGRNSATSADEQ-------------------------PHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKIDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQ-IMKDRWMNVGHEDDELKPYVEPLPDYKDPRRT------------ELMVSMGYTREEIQDSLVGQRYNEVMATYLLLGYKSSELEGD------TITLK----PRPSADLTNSSAPSPSHK-VQRSVSANPKQRRSSDQAV-PAIPTSNSYSKKTQSNNAENKRPEE--ETGRKASSTAKVPASPLPGLDRKKTTPAPSTNSVLSTSTNRSRNSPLLDRASLGQASIQNGKDSLTMPGSRASTASASAAVSAARPRQHQKSMSASVHPNKASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSSGAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPS---GHSQGRRGASGSIFSKFTSKFVRR---------NLNEPESKD-----RVETLRPHVVGSGGT--DKDKEEFR----------------EAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHERYMLLCVHGTPGHENFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIASKIANELKL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08679-1", "uniprot_id": "MARK2_RAT", "id": "O08679-1", "name": "Serine/threonine-protein kinase MARK2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMLRGRNSATSADEQ-------------------------PHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQ-IMKDRWMNVGHEDDELKPYVEPLPDYKDPRRT------------ELMVSMGYTREEIQDSLVGQRYNEVMATYLLLGYKSSELEGD------TITLK----PRPSADLTNSSAPSPSHK-VQRSVSANPKQRRSSDQAV-PAIPTSNSYSKKTQSNNAENKRPEE--ETGRKASSTAKVPASPLPGLDRKKTTPTPSTNSVLSTSTNRSRNSPLLDRASLGQASIQNGKD------------------------------------------------------STAPQRVPVASPSAHNISSSSGAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPFGVTPASPS---GHSQGRRGASGSIFSKFTSKFVRR---------NLNEPESKD-----RVETLRPHVVGGGGT--DKEKEEFR----------------EAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHERYMLLCVHGTPGHENFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIASKIANELKL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3B4V1-1", "uniprot_id": "A0A8M3B4V1_DANRE", "id": "A0A8M3B4V1-1", "name": "MAP/microtubule affinity-regulating kinase 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTRIPLLAIHDHSSGQ---SHSDSKPGGRSTMP-----HSTADEQ-------------------------PHIGCYRLLKTIGKGNFAKVKLAKHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKLLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCIVHRDLKAENLLLDADMNIKIADFGFSNEFTLGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPTKRGSLEQQIMKDRWMNVGHEDEELKPYIEPQPDYKDPKRTGQHPSSAGGWKRDIMIRMGYSLDEIQDSLINQKYNDVMATYLLLDYRNSELD--------ELSIK----ARPGTDITNN-AQSPSHK-GQRSTS-NLKSRRSTDQSS------------------VSSKRPQGDSKHIGSSGSSSKVPPSPLISGDHKKT-PTPSTNSILSSGTGRSRNSPITERATLG---VQNGKDSLHTPGSRASTASAAAVLAASSRTRHHKSLSTSAHP--------SPPDLHAHRPSTANQRAPVVSPSAQNINISS-MADRTNFSRGVTSRSTFHAGQQRATRDQQASAYNDPSASPSLSHGNSQVRRPGTG-IFSKFTSKFVRRNLSFRFPRRSPYEGEGRDEASRPMLSTADKMEKGTQGHPSDENKDSFSSSSPASSTPSSTQASKDTKPRSLRFTWSMKTTSSMEPNEMMKEIRKVLDSNSCEYELRERFMLLCMSGNPAHDDFVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZBL9-1", "uniprot_id": "A1ZBL9_DROME", "id": "A1ZBL9-1", "name": "MAP/microtubule affinity-regulating kinase 3", "aln": "MSTAMRTTLQSVPEALPADSVSNGTASNVAAPAAPVSSATNAVPPLAAVSSTTATYATNSISTSSHSVKDQQQQQQQQQHDSANANIVSLPPTTTPVANTNTMMPIVTSSNSATSNSTAATPTPASGAAATGGVGSVSQGPATVSASAANTNHSHQHSHQHHHHVANNMTTDGARLSSNNSAVVASSAINHHHHHTPGSGVAPTVNKNVLSTHSAHPSAIKQRTSSAKGSPNMQMRSSAPMRWRATEEHIGKYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLET-IMGDKWMNMGFEEDELKPYIEPKADLADPKRI------------EALVAMGYNRSEIEASLSQVRYDDVFATYLLLGRKSTDPESDGSRSGSSLSLRNISGNDAGANAGSASVQSPTHRGVHRSISASSTKPSRRASSG------------VGPTNAAATVAAATGAVGAVNPSNNYNAAGSAADRASVGSNFKRQNTIDSATIKENTARLAAQNQRPASATQKMLTTADTTLNSPAKPRTATKYDPTNGNRTVSGTSGIIPRR----------STTLYEKTSSTEKTNVIPAETNLFDRLRMASAVKSSRHFPRNVPSRSTFHSGQTR-ARNNTALEYSGTSGASG------DSSHPGRMSFFSKLSSRFSKR-------------PTIAD---------------------------------------------EAAKPRVLRFTWSMKTTSPLMPDQIMQKIREVLDQNNCDYEQRERFVLWCVHGDPNTDSLVQWEIEVCKLPRLSLNGVRFKRISGTSIGFKNIASRIAFDLKLXLNQTNNEGNAAATASRPTDPTDTMTTTNCRRPSNDSTSRLSELSLLCRSLTSQQGSQRRKKSRLSTGGSEDQKKSNSLLSAFQMYSPFSSKENMQSSEEVEDLHVIDTQPGHSVDVPLFADFSPINPIMEEDAEGVEGGKTSEAKVISGGSGQKVKGDGGGGGGGNRLKRNIKHTGSLIVRKLTAGRHNDADKKGAIRKKDKEQQEVADTDKERPTSKPEGKVAMLRTTTL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .: : . : . * ...: .:* :* *** *:*:**************:*: ******:*********..*************:*:********:**********:************** **********.*************** *:************:::************** *.********************* **************************..*:*************************:***:***:**.:** ** *:***:*.*::*****:** .* **:* : :: ***. .**: ** :*::*:******. :.:: : :::: ..:: . . **:*: :** * . .. .: . . . ..... :.. *. . .. .* . : . :* :. :*.: . : . * : : *. : ..: :. . :*.*.*.******:** * .*:: :. ...:.. : : . :***::*:* :* * :*** ***********.: *:::*::**:*** *.*: * :*:::* *: * * :.:****:**********************:.******:** :*** ", "identical_positions": 353, "similar_positions": 167, "identity": "27.8%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4146", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q791F6-1", "uniprot_id": "TPRA1_RAT", "id": "Q791F6-1", "name": "Transmembrane protein adipocyte-associated 1", "aln": "-MASLQEA---------------NGSTAWPPPTASNISEPHQCLLLLYEDIGSSRVRYWDLLLLIPNVLFFIFLLWKLPLARAKIRVTSSPIFITFYILVFVVALVGIARAVVSMTVSASDAATVADKILWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITTVLSLAYSVTQGTLEILYPDSHLSAEDFNIYGHGGRQFWLVSSCFFFLVYSLVVILPKTPLKERVSLPSRRSFYVYAGILATLNLLQGLGSALLCANIIVGLCCVDATTFLYFSFFAPLIYVAFLRGFFGSEPKILFSYKCQVDEAEEPDMHLPQPYAVARREGIESAGPACASAANYSSTQFDSAG-VAYLDDIASMPCH-TGSINSTDSERWKAINA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MU1-1", "uniprot_id": "TPRA1_MOUSE", "id": "Q99MU1-1", "name": "Transmembrane protein adipocyte-associated 1", "aln": "-MASLQEA---------------NGSTAWPPPTASNISEPHQCLLLLYEDIGSSRVRYWDLLLLIPNVLFFIFLLWKLPLARAKIRVTSSPIFITFYILVFVVALVGIARAVVSMTVSASDAATVADKILWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITTVLSLAYSVTQGTLEILYPDSHLSAEDFNIYGHGGRQFWLVSSCFFFLVYSLVVILPKTPLKERVSLPSRRSFYVYAGILATLNLLQGLGSALLCANIIVGLCCVDATTFLYFSFFAPLIYVAFLRGFFGSEPKILFSYKCQVDEAEEPDMHLPQPYAVARREGIESAGPACASAANYSSTQFDSAG-VAYLDDIASMPCH-TGSINSTDSERWKAINA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86W33-1", "uniprot_id": "TPRA1_HUMAN", "id": "Q86W33-1", "name": "Transmembrane protein adipocyte-associated 1", "aln": "-MDTLEEVT------------WANGSTALPPPLAPNISVPHRCLLLLYEDIGTSRVRYWDLLLLIPNVLFLIFLLWKLPSARAKIRITSSPIFITFYILVFVVALVGIARAVVSMTVSTSNAATVADKILWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITTVLSLAYSVTQGTLEILYPDAHLSAEDFNIYGHGGRQFWLVSSCFFFLVYSLVVILPKTPLKERISLPSRRSFYVYAGILALLNLLQGLGSVLLCFDIIEGLCCVDATTFLYFSFFAPLIYVAFLRGFFGSEPKILFSYKCQVDETEEPDVHLPQPYAVARREGLEAAGAAGASAASYSSTQFDSAGGVAYLDDIASMPCH-TGSINSTDSERWKAINA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4V8X0-1", "uniprot_id": "TPRA1_DANRE", "id": "Q4V8X0-1", "name": "Transmembrane protein adipocyte-associated 1 homolog", "aln": "MLETVTDVASFVHYGNTSVFPTADNSSEIIPDGESNISKPHRCLQVLYDDIGTSRVRYWDVMLLIPNVAFLVFLMWKLPSARAKIRLTSSPIFVAFYILVFVVAAVGITRAIVSMTVSTSSAATLIDKVLWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITAVLSLAYSITQGTLEIRFPDKHLSAKDFNIYGHGGRHFWLASSCFFFLVYSLIVILPKTPIRERISLPSKRSFYVYSGILALLNLVQGLGSALLCADIIEGLCCVDVTTFLYFSVFAPLIYVTFLKGFFGSEPKILFSYKSQIDEPEDSDVHLPHTSSSG-------LGRKDLDRGSYSSTQIDGSG--AYLDDVVSGPFGGAHSINSVDSDRWRSINT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :. :.*: * .*** **:** :**:***:*******::****** *::**:**** ******:******::********* ***:**:******:*.***: **:***************************************:*******:******* :** ****:**********:***.***********:*******::**:****:******:**** ***:*****.*** :** ******.*******.*******:**:**************.*:**.*:.*:***:. : . * . ..*****:*.:* *****:.* * : ****.**:**::**:", "identical_positions": 260, "similar_positions": 70, "identity": "67.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-415", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BWG6-1", "uniprot_id": "SCNM1_HUMAN", "id": "Q9BWG6-1", "name": "Sodium channel modifier 1", "aln": "-MSFKREGDDWSQLN------VLKKRRVGDLLASYIPEDEALMLRDG----RFACAICPHRPVL--DTLAMLTAHRAGKKHLSSLQLFYGKKQ-----------PGKERKQNPKHQNELRRE----ETKAEAPLLTQTRLITQSALHRAPHYNSCCRRK-----YRPEAPGPSVSLSPMPP-----------SEVKLQS------GKISREP-----EPAAGPQAEESATVSAPAPMSPTRRRALDHYLTLR-------------SSGWIPDGRGRWVKDENVEFDSDEE-----EPPDLPLD------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K136-1", "uniprot_id": "SCNM1_MOUSE", "id": "Q8K136-1", "name": "Sodium channel modifier 1", "aln": "-MSFKREGDDWSQLN------VLKKRRVGDLLASYIPEDEALMLRDG----RFACAICPHRPVL--DTLAMLTAHRAGKKHLSSLKLFYGKKQ-----------TGKGTEQNPRQQNELKT-----ESKTEAPLLTQTRIITQNALHRAPHYNSCCRRK-----HRPEAPAPSVSSPPLPT-----------AEVQLQS------AEISKEP-----EPRERSDAKESAALLASAPMSPTKRRVLNHYLTLR-------------SSGWVPDGRGRWIKDENVEFDSDEE-----EPPDLPLD------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2YDS5-1", "uniprot_id": "SCNM1_DANRE", "id": "Q2YDS5-1", "name": "Sodium channel modifier 1", "aln": "-MSFKREGDDQSQLN------ILKKRRVSDLLSNFIPDDEATLMKNG----RYSCLVCSHRPVF--DTVDMLVVHRKGKRHLEGMKWFYGKKN-----------QLRREIDKRRHQDYVKAEDDRQEPSSSAPLLTQTRKITHHALLRTVPYSSCHKKA-----SERSESSSKEHRNDLAN-----------SHLSMRTESNDSRTTVHQGPSEVKGEAKKKKKGASTLSSSVCEPLTEQRRRELDHYLKLK-------------SSGWLQDRSGKWVKDENVEFDSDEE-----EPTLLPPCSESS--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZSG3-1", "uniprot_id": "D3ZSG3_RAT", "id": "D3ZSG3-1", "name": "", "aln": "MSSYQKELEKYRDIDEDEILRTLSPEELEQLDCELQEMDPENMLLPAGLRQRDQTKKSPTGPLDRDALLQYLEQQALEVKERDDLVPFTGEKKGKPFIQPKREIPAQEQITLEPELEEALSHATDAEMCDIAAILGMYTLMSNKQYYDAICSGEICNTEGISSVVQPDKYKPVPDEPPNPTNIEEMLKRVRSNDKELEEVNLNNIQDIPIPVLSDLCEAMKTNTYVRSFSLVATKSGDPIANAVADMLRENRSLLSLNIESNFISSTGLMAVLKAVRENATLTELRVDNQRQWPGDAVEMEMATVLEQCPSIVRFGYHFTQQGPRARAANAMTRNNELRRQQKKR", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:::* :. ::: *. ..: :* .. * :: . * .. *: : * : :. ..: * *:*: : . : * *.:* ::: : .. . . . . . . .:. : *. : : . . . : : *:* : . : .*: *:: :. : ", "identical_positions": 19, "similar_positions": 70, "identity": "5.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4153", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2KJ09-1", "uniprot_id": "UBP16_RAT", "id": "Q2KJ09-1", "name": "Ubiquitin carboxyl-terminal hydrolase 16", "aln": "MGKKRTKGK---------------------SVPEKASSESTEPMCRHLRKGLEQGNLKKALVN-VEWNICQDCKTDNKVKDKSEEEAED----------------PSVWLCLKCGHQGCGRDSQEQHALKHYTTPRSEPHYLVLSLDNWSVWCYKCDEEIKYCSSNRLGQVVDYVRKQAG--------------------------------------------------------------------RITSKPAEKNNGHIELENKKLEKESKNEQEREKSESMAKENI------PLDSASQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEP-------LEVNLEPPGPLTLAMSQFLNEMQENKKRIVTPKELFSQVCKKATRFKGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLD---EEVKNKVKDYEKKKAIPSFVDR-IFGGELTSTIMCDDCRTVSLVHESFLDLSLPVLDDQSGKKNINDKNVKKTMEEEDK-----------------DSEE-EKD-DSYMKTRSDVPSGT-SKHTQKKAKKQAKKQAKNQRRQQKIQERFLH--FNEICTTNYTEDNDHEAETALPGE--------GEVDTEFNRGSQEELTQTELCANQKDVNGQEEMIESAADERKCPEHPEVKSVSTESDLGSLTSAPECPRDLNGAFLEERTSGELDITNGLKNLTLNAAVDPDEISIEILNDSHSP--------------------------------------------------------------------------ALKVYEVMNEDPETAFCTLANREAFSTDECSIQHCLYQFTRNEKLQDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLVSLAPPVLTLHLKRFQQAG-FNLRKVNKHIKFPEILDLAPFCTLKCKNVA---EESTRVLYSLYGVVEHSGTMRSGHYTAYAKERTASC----------------------------------------------------------------------------HLSNLVLHGDIPQDCEMESTKGQWFHISDTHVQAVPITKVLNSQAYLLFYERIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LG0-1", "uniprot_id": "UBP16_MOUSE", "id": "Q99LG0-1", "name": "Ubiquitin carboxyl-terminal hydrolase 16", "aln": "MGKKRTKGR---------------------SAPDTVASESAEPVCRHLRKGLEQGNLKKALVN-VEWNICQDCKTDNKVKDKPEEEAED----------------PSVWLCLKCGHQGCGRDSQEQHALKHYTTPRSEPHYLVLSLDNWSVWCYKCDEEVKYCSSNRLGQVVDYVRKQAG--------------------------------------------------------------------VRTSKPAEKNNGHIELENKKLEKESKNEQEREKSENLAKETI------PMDSASQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEP-------LEVNLEPPGPLTLAMSQFLSEMQENKKRVVTPKELFSQVCKKATRFKGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLD---EEVKNKVKDYEKKKAIPSFVDR-IFGGELTSTIMCDECRTVSLVHESFLDLSLPVLDDQSGKKSINDKNVKMTMEEEDK-----------------DSEE-EKD-DSYMKSRSDLPSGT-SKHLQKKAKKQAKKQAKNQRRQQKIQERFLH--FNELCATDYTEDNEREADTALAGE--------VEVDTDSTHGSQEEATQIELSVNQKDLDGQESMIERTPDVQESPEDLGVKSANTESDLGIVTPAPECPRDFNGAFLEERTSGELDIINGLKNLNLNAAVDPDEINIEIPNDSHS---------------------------------------------------------------------------APKVYEVMNEDPETAFCTLANREAFSTDECSIQHCLYQFTRNEKLQDANKLLCEVCSRRQCNGPKANIKGDRRHVYTNAKKQMLVSLAPPVLTLHLKRFQQAG-FNLRKVNKHIKFPEILDLAPFCTLKCKNVA---EESTRVLYSLYGVVEHSGTMRSGHYTAYAKERTASC----------------------------------------------------------------------------HLSNLVLHGDIPQDCEMESTKGQWFHISDTHVQAVPITKVLNSQAYLLFYERIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5T5-1", "uniprot_id": "UBP16_HUMAN", "id": "Q9Y5T5-1", "name": "Ubiquitin carboxyl-terminal hydrolase 16", "aln": "MGKKRTKGK---------------------TVPIDDSSETLEPVCRHIRKGLEQGNLKKALVN-VEWNICQDCKTDNKVKDKAEEETEEK---------------PSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEVQYCSSNQLGQVVDYVRKQAS--------------------------------------------------------------------ITTPKPAEKDNGNIELENKKLEKESKNEQEREKKENMAKENP------PMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEP-------LEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLD---EELKNKVKDYEKKKSMPSFVDR-IFGGELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQ-----------------DSEE-EKDNDSYIKERSDIPSGT-SKHLQKKAKKQAKKQAKNQRRQQKIQGKVLH--LNDICTIDHPEDSEYEAEMSLQG----------EVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMKNINMDNDLEVLTSSP--TRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILNDSHTP--------------------------------------------------------------------------GTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAG-FNLRKVNKHIKFPEILDLAPFCTLKCKNVA---EENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANS----------------------------------------------------------------------------HLSNLVLHGDIPQDFEMES-KGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8HAL1-1", "uniprot_id": "UBP16_DANRE", "id": "A8HAL1-1", "name": "Ubiquitin carboxyl-terminal hydrolase 16", "aln": "MGKKKVKDR---------------------SAGTDSSSETAGPSCTHIRKGTENSVLKKACLN-EHWSSCQDCEQDKPEEKQILEDQTDG-------------ESPAVWMCLKCGHRGCGR-SGNQHAIKHYETPRSEPHCLVLSLDVWSVWCYICDDEVQYSSTGQLAQLITNIRKQVLTAPD---------------------------------------------------------------KRNASKKSWKEDISVMNSAEQTQDEEKGKKGKQKSSSKQEDSPKSHQSAAAGSSAVVSVRGLSNLGNTCFFNAVVQSLSQTQYLRELLKQIAEEKSSFSITPALSSELDP-------LQIQLERPGSLTLAMCQLMNEIQETKKGVVTPKELFTQVCKKAPRFKGFQQQDSQELLRYLLDGMRAEEAKRVNSGILEALKSSGKNFEA--EQTKKIVKEYEKDGAPKNFVDR-VFGGAMSSTVMCKECKTVSLVTEMFLDLSLPVADEAYRK-----KNQKKAVQHRHS-----------------VSDDGDQDTSSLANGNEDMPTGTGSKYQQKKAKKQAKKQAKNQRRQQKQGGKVTLDAITNQSSTDPADSSMQTQTVSVNG----------SADAQPADTNQEDLSLEKHNEDQDDEEPEQEQAASVNN-----RFTALSEDQTTEDIAEQVNEDE-------DEIEQNCAEEEELVEELNTMSLTTPSEGD---VEN-GEDTLE--------------------------------------------------------------------------DVKEYTVVNRDPELAFRALASRTAPVKQECSVESCLYQFTEVEHLTENNRLMCVTCTKQQP----GYKDGCKKAVYRDALKQMLISDPPVVLTLHLKRFQQVA-YSVCKVNRHVQFPQILDLAPFCSLNCTGVK---EGETQVLYSLYGIVEHSGTMRSGHYTAYVKSRPS-------------------------------------------------------------------------------THNCVQNGTAAASGDAEASKGSWFHISDSSVHPVPEAKVQSSQAYLLFYEKIS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4C3-1", "uniprot_id": "UBP64_DROME", "id": "Q9W4C3-1", "name": "Ubiquitin carboxyl-terminal hydrolase 16/45", "aln": "MVKKRQADSRDHDCSTDSGNEDLHHRKGLGSPGQSDGATPTTASCQHIKKAVDAARLRRLLKSTGLLYECSQCQKLGKTAGSAAGAGASEGAVGPGGNPVTFEFDNTLWLCLKCGSQLCGR-ARHKHALEHYQTPHSDSHALAMNTRSFDIWCYECDMKICSNLRKNLLECVELVKKLAQKPPTSTVTPSTPTISYIEEKLKAALEHLTPIVPMTGGSFDDSSSRGSLAAAGGGGGVGSSRNRQVAIPMPPPEPSSGLSTSDSLTSVPGMAKRIDQYSATTNGNTGNKRLLTLETPRIENERLPRVRGLTNLGNTCFFNAVMQCLAQTPFLLSVLKELSEPGEEFILPGGTFTIKDKGDIELPMIKGTLSSWGGLTAALANALEELQAGG-SVFTPRKLFDRLCVKCPQFTGGDQHDAHELLRQLLESVRNEDLKRYQRVILQNLGYKDQDVNSVSEEMRQKCKIYGNQAGDRILRPEQVFRGFLVSTLTCQDCHNVSSRHEYFLDMSLPVAVEKPQPPQRRKPSPELSLTSSSSSVTPSTGQPTINTKFTDGSVNFTASSPSFFLHAHEAASLGPSKSQVKKEKERQRKAKRAAKKRQKSSLNLNGNDSGNGNELAESVDQDDASLASLGAGDGQANDGLEQTNGQTEDSTTSSVTTSEHSDADVEDNLVEDTAAPSTNNVPSSTASLTAPSKTYMDSNGNAQPPGEKRDDTPEHMDKDSLEEDENDSGIATSPAPTATNSSTSTSATGNNNSVAGSGLSGSSGALEDPLAPASLVTAGLSEKGASVIRQVSVGAEQGASNGTEDADGEAKAIEQPEKTPSQAQAMAQAQARTKRVRTQSYSDWSTTIAPRYQCEDGECSVQSCLNNFTAVELMTGQNKVGCDSCTQRIN-----GSDPKAKSVNTNATKQLLVSSPPAVLILHLKRFQLGPRCIFRKLTRPVSYPNLLDIAAFCGSKVKNLPNIDRKQKKLLYALYGVVEHSGGMYGGHYTAYVKVRPKVAPGDKRWKFLPHGSKAELDQDDDQLKKLEELLAKEKAREQHLKVLDDSDDFSNSSSNSSTSDESQTPATPLEEQQTQQAQQPQQPQQLEEAANVRAPPGKWYYVSDSRVQEVSEDTALKAQAYLLFYERIY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **: . : .: . . * *::*. : . *:: . *.:*: . . ::*:***** : *** : .:**::** **:*:.* *.:. :.:*** ** :: .* : : ::* . ..: : . : .: .. . :. . *:**:***********:* *:** * .:**:: . : : : :: *. * ** *:.: :.*:* :.**::** ::* *. :*.* :*:*::**** **:.:* *: :* . **: : . :..: *: :: * * :. . : . :* * : * : *.:*:.** * ***:**** : . : :: . * : . * : .: ** ** *:: :* : :::** .. : . .. :: . ..: . . . : : : : . : . * . : : * : . : . :. . . .:. : * ... . ::* * ***:: ** :** * : *:: * *::: . : * :* **:*:* .* ** ******* . *:.: :.:*::**:*.** : ..: . ..::**:***:***** * .******.* *. : : .: *.*:::**: *: *. .. .:********:* ", "identical_positions": 184, "similar_positions": 240, "identity": "16.24%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4154", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F6U5V1-1", "uniprot_id": "F6U5V1_MOUSE", "id": "F6U5V1-1", "name": "", "aln": "---------------------------------------------------------------------------------------MSARAPVPAAATREDPPAVAGDRDALLAATSRRAEQPAPGEREGKEAREERAAAATSAGARGEPSPALVLG--------HSVPQAAVPVRPLALHLAHKARAPGGPFGGEAPPLPPPPPPPPPPPPPLPPPAPRDPPEDAREDP-------------------AAAGPEDKPPPPPPKGNPWTKKLPQHLSTVG-----------------------------------------------------------------------------------------TGVPSPAQDSPEAELSSPKIIKAGKLKTKKSNKASDFSDMANWPTPG------------------------------------------------ELVNTGSQS--VINQGNKKPQIRKEKEEKIEKRSNSESKENREAKLDGPTENISEDEAQSSSQRKRANKHKWVPLHLDDVRPDSQERPGSRNSSRC-----------------------------QPEANKPTHSNRKSDTRSWRREREKRDDQDEVSSVRSE---------------GGTIRGSTRGRGRGRGRGRGRG----RGNPRLNFDYSYGYREPGERTEQPFSTELNTS-------MMYYYDDGTGVRVYPVEETLLKEYIKRQIEYYFSTENLERDFFLRRKMDEQGFLPISLIAGFHRVQALTTNLNLILEALKDSTEVEIVD-EKMRKKIEPEKWPIPGPPPRN--------VPQTDFSQLIDCPEFIPGQAFGSHTVR----VMIY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZWA7-1", "uniprot_id": "A0A8I5ZWA7_RAT", "id": "A0A8I5ZWA7-1", "name": "", "aln": "---------------------------------------------------------------------------------------MSARAPVPAAAPREDPPAVAGDRDALLAAASRRAEQPAPGEREGKEAREERAAAATSAGARGEPSPALVLG--------HSVPQAAVPVRPLALHLAHKARAPGGPFGGEAPPPPPPPPPPPPPPP---PPAPRDPPEDVREDP-------------------AAAGLEDKPPPLP-KGNPWTKKLPQHLSPVG-----------------------------------------------------------------------------------------TGVPPPAQDSPEAELSSPKIIKAGKLKTKKSNKASDFSDMANWPTPG------------------------------------------------ELVNTGSQS--VISQGNKKPQIRKEKEEKIEKRSNSESKENREAKLDGPIENVSEDEAQSSSQRKRANKHKWVPLHLDDVRPDSQERPGSRNSSRC-----------------------------QPEANKPAHNNRKSDTRSWRRDREKRDDQDEVSSVRSE---------------GGTIRGSTRGRGRGRGRGRGRG----RGNPRLNFDYSYGYREPGERTEQPFPTELNTS-------MMYYYDDGTGVQVYPVEETLLKEYIKRQIEYYFSIENLERDFFLRRKMDEQGFLPISLIAGFHRVQALTTNLNLILEALKDSTEVEIVD-EKMRKKIEPEKWPIPGPPPRN--------VPQTDFSQLIDCPEFIPGQAFGSHTVR----VMIY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q659C4-1", "uniprot_id": "LAR1B_HUMAN", "id": "Q659C4-1", "name": "La-related protein 1B", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENWPTPS------------------------------------------------ELVNTGFQS--VLSQGNKKPQNRKEKEEKVEKRSNSDSKENRETKLNGPGENVSEDEAQSSNQRKRANKHKWVPLHLDVVRSESQERPGSRNSSRC-----------------------------QPEANKPTHNNRRNDTRSWKRDREKRDDQDDVSSVRSE---------------GGNIRGSFRGRGRGRGRGRGRG----RGNPRLNFDYSYGYQEHGERTDQPFQTELNTS-------MMYYYDDGTGVQVYPVEEALLKEYIKRQIEYYFSVENLERDFFLRGKMDEQGFLPISLIAGFQRVQALTTNLNLILEALKDSTEVEIVD-EKMRKKIEPEKWPIPGPPPRS--------VPPTDFSQLIDCPEFVPGQAFCSHTES----APNSPRIGSPLSPKKNSETSILQAMSRG-------------------LSTSLPDLDSEPWIEVKKRHQPAPVKLRESVS--------------------------------VPEGSLNQLCSSEEPEQEELDFLFDEEIEQIGR--KNTFTDWSDNDSDYEIDDQDLNKILIVTQTPPYVKKHPGGDRTGTHMSRAKITSELAKVINDGLYYYEQDLWMEEDENKHTAIKQ-------------------EVENFKKLNLISKEQFENLTPELPFEPNQEVPVAPSQSRQGGVQGVLHIPKKDLTDELAQKLFDVSEITSAAMVHSLPTAVPESPRIHPTRTPKTPRTPRLQDPNKTP-----------------------------------RFYPVVKEPKA-IDVKSPRKRKTRHSTNPPLECHVGWVMDSRDRGPGTSSVSTSNASPSEGAPLAG-SYGCTPHSFPKFQHPSHELLKENGFTQQVYHKYRRRCLSERKRLGIGQSQEMNTLFRFWSFFLRDHFNKKMYEEFRQLAWEDAKENYRYGLECLFRFYSYGLEKKFRREIFQDFQEETKKDYESGQLYGLEKFWAYLKYSQS-KTQSIDPKLQEYLCSFKRLEDFRVDPPISDEFGRKRHSSTSGEESNRHRLPPNSS-------------------------------------------------TKPPNAAKPTSTSELQVPINSPRRNISPESSDNSH--------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TBB5-1", "uniprot_id": "A0AB32TBB5_DANRE", "id": "A0AB32TBB5-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------MTTEVASDLDVTIGCLGE-------GNQNKSDADRPEQADRTTSHEEGQQDPPQGDT--------KHPKQGVMESKADGLSTDSTN--------------------------------DKENEQNVSSHE-------------------AETAKKKVVEAPPPKVNPWTKRNSCPPNNTN-----------------------------------------------------------------------------------------NSSQQTEPQSP------AKVVRASKPRSRKTSKSSDFSDITNWPTPG------------------------------------------------ELANKEQQQNVINTQGRKGTSGRRER-----KKDHGGEKRDKESGSDGS-DSKENREAQSNSITGLSNEQ-------------------------------------------------------EAEDGEETHSSAPRRRGGWRRER----DFFDTASVRSE---------------GSNVRGGLRGRGKGRGRGRGRG----RGRG----DYSLSYRDS-YLDGNSVPAEFGTN-------MVYYYNDGNRVQMYTIEENLLKEYIKRQIEYYFSLPNLERDFFLRRRMDSKGFLPISLIASFHRVQALTTDINLIKEALKNSEVVELVD-EQIRRKEEPEQWPIP-ALALD--------SPRTDFSQLINCPEFVPGQTFTSLSTVSSSPVNQHMDEPSLVNGQTSDETDTAKPQSKESSPSDSKSSSGEDGSNLKERSSSLSDPDAQPWIQVEKRHRNTSGKNKTSVTPLPPSPPSSPPPPPPPSPPPPIPRLEFFPSAERTELVQSTPKPQPEADQEELDFLFDEEMEQLAAPRKNTFTDWSDDDSDDELDDRDVNKILIVTQTPPHLRKHPGGDRTGNHVSRAKITADLAKAINDGLFYYEQDLWTKEEGPPECANAKNNFDYHYDGIHQPDLTKCNEMENFKKLNMISQDEFETLTPKLPIDPNQEVPPPPP-----------------------------CQTDDSSMAHSLPADVPESSSVP--RTPRTPRTPGRQDPTKTP-----------------------------------RFYPVIKEDSGNLDGKTPRKRKTRHSSNPPLECHVGWVMDSREHRPRTSSISSSNASPSEGAPALSGSYGCTPQSLPKFWHPSHELLRENGFTQQVYHKYRRRCLNERKRLGVGQSQEMNTLFRFWSFFLRDNFNRKMYEEFRQFAVEDSKENYRYGLECLFRFYSYGLERRFRPDIFKDFQEETVQDYEKGQLYGLEKFWAFLKYSKV-KNQDIDPKLKEYLSKFKSIDDFRVEPPMAEEGMRRKAHSSAGDEVKRRRHNSTSS-------------------------------------------------SKQTQITKTSSDNQTTAKTAHDQAGASAATKSTNQPAAKAASANQKPAPLTAKSSSANEQPAKAPPKENVKKNTSSDARKAEAGTSKNKEAQQPKK-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAW5-3", "uniprot_id": "LARP_DROME", "id": "Q9VAW5-3", "name": "La-related protein 1", "aln": "MSSKEETPSTGGAAPVATVAASGSATTSYANVVQNLETKKSGTSNTTTTTARATVDNKENQPNLKSFKSWSEEAAAAEAAGESPIVGSVSLAQTGEKRAAASGGDNTAENSSELDDNNDFVPVLSHHRRDRKKARKEKPRDQQPAGGRGDGQKPQQAGGRRVPGSSDTERKSVRPRAPRGGSPRKSAAGAAGAAGSNAGAVSSAVPGGPKVHKDRKDTSPSASIEGAGSSGNEAKSADGDQQAGEKGAAGAAPPPKRFIAAPPPKVNAWKISAKQSGSPKAGTSPLDKRVLQPKAQQQQQQTKQTASQNNNAQNTASNKKTQQQQQPQQGATTTTQTTTAAAAAATAAAAATAATTSAAAATSSAAAVPAATTETATTTTVDASQADALAKVVVKDKKKVNQKASDFSNVGDWPTLIGGTSGSGKATSNEPKRNPTKKQQSAKTAAAVAASSNTTSSEVATESNVAGTTSSSNSNPSSSTTTTNTTTNSQATTAPVASTSHDAKAQRDAEPAANSAAGTTGTAAGPALTKKIPKHKWRPLPIDLAKSSRPKPIGGRPNRRFSDDIADQRRPPRVYHDRQPGAGGAGVESRHPHAGRHPYGSRPATATSERVDSWRSSSSTTTAAFDEQRSGAAGGAGAAGTGVGSATRGPRRYRTPYRGGRQGRGGFSRQGPGRPTYRIPRHLLASGEYANYLPADAAGADSQSSYVLMGTHYFGNVPAAYIELDANSIKEAIKKQVEYYFSVDNLTGDFFLRRKMDPEGYIPVTLIASFHRVLALTTDVAVIVNAIKESDKLELFEGYKVRTKTTPTTWPITEVPEVNEGEPKAIGTLEQEQLEQNDGQEKLEEQTEADSPPPILTSAMATKPLNSIPPPPMPRNPQNLVPKMLQDKQQSRSSTIAALNSVNAISALTQQVEGGAAELAGHLSGLAESVKPKSTSTPDKRNAASAGNGAGSAAALVAEPEGIWKEVKRRSKTNAIKENATTPPQQQQPPLSQTLNNNNDNVKTNNTSSKSKSSSNNAPSNASSSATVCVTTNNASSATKATTKTTTTSTATTTTNNNIKSGNAAYSKTHSKSSSKTAAPPSAQCHAEKEELDFQFDEELMDPLPPGTGRINNFTENFSDDDESDYEFADRDINKLLIVAQVGRAPKHEGYDRTADFTSRTKITQDLENIINDGLVNYEEDLWTTTNVVADYKTVNVISQADFEKLAGGRNKSVLPPQVVPPPPPFEEDLDETLVGDTTLNSTLNNTLKSRRARFYAAPNSHSIDPRTPRKRKLRHTANPPVEAHVGWLLDTVEHRPRTTSMG-SSAGTSPTASSYGSFGSSVPQSLPVFQHPSHALLKENNFTQQAYHKYHSRCLKERRRLGYGQSQEMNTLYRFWSFFLRENFNKSMYNEFRSLALEDAGNGFRYGLECLFRFFSYGLEKKFRPNIYQDFQDETIADYETGQLYGLEKFWAFLKYYKNGEKLEVQPKLAEYLKSFKNIEDFRVVEPEINEMLQGVGSLNPGRQLNRHRSVSESDGTAVIAAGGRRLNTTITNRSDYVGRLLQQQHQQQQQQQHHQYQQGYGGYNQQQNRRRTGSFGSTTVRIRSGSLGNKPQVANRNQGSQHELRRGGSNSGLAPHKRQQQQKPKPGAGSQTGSTRATTSAAATATTAASAATSTAATPAVTVSSGSSSSKK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*** ... :. . . . . : * :::: . * . :: ... .. .:.. . : : . .::. .: *. ** * * ** :*** :* . .:. * :* .. . :: :** **:*:***** ** ***** :** :*::*::***.*:** ****:: :* :*:*:* :*:.: ::* * * ***. . : : : * : *: . . . ", "identical_positions": 62, "similar_positions": 85, "identity": "3.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4155", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WBZ9-1", "uniprot_id": "B1WBZ9_RAT", "id": "B1WBZ9-1", "name": "", "aln": "-----MAFDTHHVKKRNFSN-----SIDLPRKRISNFTSKNMKEVKISPKQLAAYISRTVGQAVKSPDKLRKVLYHRKLVRHSFPNPCYKTKQSPRSGGCDMANKENELACAGHLPENLHHDSRTFVINTSDSGSSQTENPSSKYSGFFSEVSQDHETMAQVLFSRNLRLNVALTFWRKRSVSELVAYLVRIEDLGVVVDCLPVLTNSLQEEKQCISLGCCVDLFPLVKSLLQSRFEEYVIVGLNWLQAVIKRWWSELSSKSEIIS-----DGNIKILKQQLNGLWEQENHLTLVPGYTGNIAKDVDAYLLQLH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWJ3-1", "uniprot_id": "KTBL1_MOUSE", "id": "Q9CWJ3-1", "name": "KATNB1-like protein 1", "aln": "-----MAFDTHHVKKRNFSN-----SIDLPRKRISNFTSKNMKEVKRSPKQLAAYISRTVAQAVKSPEKLRKVLYHRKLVRRSFPNPCYKTKQSPKSGGCDMANKENELACAGHLPENLRHDSRTFVINTSDSGSSQTESPSSKYSGFFSEVSQDHETMAQVLFSRNLRLNVALTFWRKRSISELVAYLVRIEDLGVVVDCLPVLTNSLQEEKQYISLGCCVDLLPLVKSLLQSRFEEYVIVGLNWLQAVIKRWWSELSSTSEIIS-----DGNIKILKQQLSGLWEQESHLTLVPGYTGNIAKDVDAYLLQLH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H079-1", "uniprot_id": "KTBL1_HUMAN", "id": "Q9H079-1", "name": "KATNB1-like protein 1", "aln": "-----MASETHNVKKRNFCNKIEDHFIDLPRKKISNFTNKNMKEVKKSPKQLAAYINRTVGQTVKSPDKLRKVIYRRKKVHHPFPNPCYRKKQSPGSGGCDMANKENELACAGHLPEKLHHDSRTYLVNSSDSGSSQTESPSSKYSGFFSEVSQDHETMAQVLFSRNMRLNVALTFWRKRSISELVAYLLRIEDLGVVVDCLPVLTNCLQEEKQYISLGCCVDLLPLVKSLLKSKFEEYVIVGLNWLQAVIKRWWSELSSKTEIIN-----DGNIQILKQQLSGLWEQENHLTLVPGYTGNIAKDVDAYLLQLH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58I213-1", "uniprot_id": "A0AC58I213_DANRE", "id": "A0AC58I213-1", "name": "", "aln": "MESIIMATGSHVGSNAEVHRLKQAQPHDLLKRMLCSGDEKNMREVDYLLKDETDQERFPVGRCVHKYSKTKREVVGKKKTRLSGVGPRACRKLPTTSRTSDMANKENELTCVDEVQAFLYSDNCGFPVNSTD---AKMAGAGSKYSDYFTELSKDHEAMSHVLFGRNLRLNVALTLWRKN-ASELVAYLNRIQDTGVLVDCLPVLTKSLQGEQPCISLGCCVDLFPQVKMILNTKYEEHLIVALHWVQSIIKKWWSELSTNNKSLPESSSNDRNVQAMKTMLLELWQGKSHLSSVPGTVGETAKVIESYVSQLR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** :* .: :. . ** :: :.. .***:**. *: : .*.: *:. .* :: : :* .: . .* * .. * .*********:*...: * *. : :*::* :: ...****.:*:*:*:***:*::***.**:*******:***. ******* **:* **:********:.** *: *********:* ** :*::::**::**.*:*:*::**:******:..: : * *:: :* * **: :.**: *** .*: ** :::*: **:", "identical_positions": 126, "similar_positions": 98, "identity": "40.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4156", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7Z5L2-1", "uniprot_id": "R3HCL_HUMAN", "id": "Q7Z5L2-1", "name": "Coiled-coil domain-containing protein R3HCC1L", "aln": "MQQESER--------CRVRARRPDMALYVPKARRGAVLLKTGDEEESCGSPNSVVKEKQKESSLSQKEVFKDKPEARRLNINPDRKEHNCREEKKSSTKLRMDTCLQKTN--RVCSKRGTTESKEVLSQGQQQGAPNAGVITNAPLQRHFKPKKVECLEVETTDVTGHERILLSQACLEISEAQVPSKPFQNVEFCDFSRHEPDGEAFEDKDLEGRIETDTKVLEILYEFPRVFSSVMKPENMIVPIKLSSDSEIVQQSMQTSDGILNPSSGGITTTSVPGSPDGVFDQTCVDFEVESVGGIANSTGFILDQKDTDSIPATMGHISLS-------ESTNDTVSPVMIRECEKNDSTADELHVKHEPPDTAVLAHETHRDSGFKNVGDITNKACMMDTTGMSCSDHVTVDSPYVVAVRIADETSINTRSFSKFVGMSADATPLHVARSGNDTEDFSNPSACSDIYGESISSHFTESTGKLIESLSDCASSLPIKKIAGSNYNTFLDSELSMLNGTKVLSDSAVGIDLGSTGDTTEALHELRTAEEFKTEEQDDSGSIEFGVSFPDRESSSMETSIEPKATETSHTEGITAIEESWESMFNDDGDCLDPRLLQEGILMHIKPENHCSKLSGNTKSRESIQEPRSDYYNHEVPD---IDLSDCEFPHVIEIYDFPQEFHTEDLLRVFCSYQKKGFDIKWVDDTHALGVFSSPITARDALGIKHTMVKIRPLSQATRAAKAKARAYAEFLQPAKERPETSAALARRLVISALGVRSKQSKTEREAELKKLQEARERKRLEAKQREDIWEGRDQSTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BJM3-1", "uniprot_id": "R3HCL_MOUSE", "id": "Q8BJM3-1", "name": "Coiled-coil domain-containing protein R3HCC1L", "aln": "MQQEAER--------CRVRTKRPDMALYVPKARRGTALLKSSDQEEGHGPPAFVPKD-QKEGCLPQKISASKPESQRRGAGHSDRKDVDCREGKRSASQLRKDRCPQKQNKEKACSKKGAEESTEASSQEHQHRAPDAGIVSSIPLQRLFKPKDMDCWEVQTAGATGHWRVSPSQSSSEVSAAQVPSRPFQNVELCDFS-----GETFVNRNLESSIVTEAKVPELVSQFPQVVTTLLKPDGMAMPVTLSSDSETAPSSLETPDGMSKHSPGDISVVSVPGGPDEDVDSTFVDFEVESEG-TVNSTESVLGQKGVDSILETVDNVSLKMAVVSKLESTNGTIDPAVTRECE-SDSSADELCVKSEPSDTAVLVHEIDTDDGFRNVCDSTSKACMVDIAGTAC-DPVTEGSSCTGAVGESGESSGNMRNFSDYIEMSADVAPLDRAKSENDSENISSLSACSDIYAESIASGFTESTGKLIESVSDGASSLPIKKTADSNIATCLDSELSMSDASDVLLESALGSDLDTTEEMTEALHDLKTAEEFKTKEEDYSESVVCGISFSD---SSVETSVDLKTTDTSHIQGSSAVEESWESMFNDDGDCVDPRLLLE--------------LSGNVKNRKSIQEPRFDYYSHELPD---IDLSECEFPHVIEIYDFPQEFRTEDLLRIFCSYQKKGFDIKWVDDTHALGVFASPITARDALGTKHTMVKIRPLSQATRAAKAKARACAEFLQPAKERPETSAALARRLVISALGVRSKQSKTEREAELRKLQEARERKRLEAKQREDIWEGRDQSVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F1G4-1", "uniprot_id": "E7F1G4_DANRE", "id": "E7F1G4-1", "name": "", "aln": "METEAAQPEQGSKTAVPARTKRPTMEVYVPKKRQ----AEKTDKPQSDG----------------------DKKSKPR-----PRYTDKARKNKKDKAKVS---------------------------------------------------------------------------------------------------------------------------------------------------------------ETQNGEIKPDAG------------------------EQGG-----------------------------------------------------------------GGDTENQNTEPEKDE---------------------------------------------------------------------------------------------ESTG-----------------------------------------------DMNTTSRTVHSPEDSSSVLEHDDEEMKDE-------------------------------------EENWDSLFNDDGDCLDPHLMEEMS------------LKEGRK-KQSAQDSGFDYYNWSPQDDEEVELRDDELSHIIEIYDFPTEFKTEDLVRSFSSFQQKGFDITWIDDTHALGLFSSPIAARDALRMKNPMMKVRPLSSSSNATKAKARSCSDYLLPAKERPQTSAALARRLVIGALGVKSNQTREEREAERNKLQQAREQKRLAAKQREDAWEGK-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *: : .*::** * :**** *: :. *: :. * . . * * ..*: *:. ::: :* :* : ..* *. * ** * . *. **** *:.:* ..: .: :. *.. :* . . **.*:*:*******:**:*: * *. . * ::* *:. ***. . * ::* : *:.*:******* **:****:* *.*:*:*****.*:*******:*:***:***** *:.*:*:****.::.*:*****: :::* ******:***********.****:*:*:: ***** .***:***:*** ****** ***: ", "identical_positions": 159, "similar_positions": 99, "identity": "19.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-417", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q13835-1", "uniprot_id": "PKP1_HUMAN", "id": "Q13835-1", "name": "Plakophilin-1", "aln": "MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSSTLSHSNRGSMYDGLADNYN-YGTTSRSSYYSKFQAGNGSWGYPIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCNTTG---AGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGSKGQKTTQNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCN--KDLSFGHSRASSKICSEDIECSGLTIPK---------AVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAG-RQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTG-----CFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNS---EDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSAS-PKAAEAARLLLSDMWSSKELQGVLRQQGFDRNMLGTLAGANSLRNFTSRF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97350-1", "uniprot_id": "PKP1_MOUSE", "id": "P97350-1", "name": "Plakophilin-1", "aln": "MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSSTLSHSNRGSMYDGLADNYNNYGTTSRSSYFSKFQAGNGSWGYPIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCATPG---AGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGSKGHKTTQNRCSFYSTCSGQKAVKKCPVRPPSCTSKQDPVYVPPISCN--KDLSFGHSRASSKICSEDIECSGLTIPK---------AVQYLCSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTPNKLETRRQNGIREAVSLLRRSGSTEIQKQLTGLLWNLSSTDELKEELVADALPVLTDRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLR---------------------NLSSADAG-RQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCILHNLSYRLDAEVPTRYRQLEYNTRNAYTEKSSTG-----CFSNRGDKMMNNNYDCPLPEEETNPKGSSWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSNGMSQLIGIKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPVLHRVMGNQVFPEVTRLLTSHTGNTSNS---EDILSSACYTVRNLMTSQPQMAKQYFSNSMLNNVFNLCRNTASSPKAAEAARLLLSDMWASKELQSVLRQQGFDRNMMGNIAGANNLRNFTSRF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FBR0-1", "uniprot_id": "E7FBR0_DANRE", "id": "E7FBR0-1", "name": "", "aln": "MMPEPLKSALS---LGNMEDTSLAVPSDIEHRSAQQRVLEQVHTIKKSKSKYRSKSKSVSALATSPTSPEGDSVFYDFKFSPGTSLSG--PSFNRGGNMTNGAMQRQNILRKSTNSRSSSGQQVNSNSGRFDRSIYGFQGSVSTQQKTSNQLYNKSTRSAPDLGFQP----TTNGMSSTGQRSQTSRQTFQRWEKGSQMPSSSYSNGTTLVRMSNSNQVNAVSRRPSSLQSNGESRMSMIRSGQAKDFSGMTLEKPVSDMTMRDAVDCLSSTDENVQLCGASYIQHSTFNDDKAKQEVLTLKGLPLLVDLLGSSSPQVQETVAAALRNAIFKNLPNKQEVQRSGGIKQAAQLLG-DANTETQKHLTGLLWNLSSEDGLKPDLLRTALPALTEKVIEPFSANTVDNANTS---LAPEVFCNATACLR---------------------NLSGSKLANRQSMRNCKGLIDSLMRYTENCITAGMPDNQSLENCVCILHNLTYQLETEMPTLFNKINALASQSHNRSSSSDAGPIICFRLQSQKLKQRGFDYPVMED-NNPEGVGWLFHSKALQFYLNLLSSSERDATLEACCGTLQNLTANEGIVSNFLSQTIVQKLNGMKFITPLLQSTNPALQNSAVALLGNLSKSSQTNKVMAPQSLPQLVGFLNSGLSKKESSPEYDSAMATALRSANTLINADPDTGKNLLNNSLINNLYNMS-LNRDLQKSSKASALLLHNLWSNKNIQSFLKKNGMKKKSFVNEVTSAAFKSHLVID", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 249, "similar_positions": 283, "identity": "32.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4172", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NF91-1", "uniprot_id": "SYNE1_HUMAN", "id": "Q8NF91-1", "name": "Nesprin-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATSRGASRCPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRK-------IKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQEDDEILPGFPSFANSVQNFKREDRVIFKEMKVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQSWDRVTSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALREEITVQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGS-VEEAENVMKFMNETTAQWRNLSVEVRSVRSMLEEVISNWDRYGNTVASLQAWLEDAEKMLNQSENAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYAQADEMDRMKKEYTDCVVTLSAFATEAHKKLSEPLEVSFMN-VKLLIQDLEDIEQRVPVMDAQYKIITKTAHLITKESPQEEGKEMFATMSKLKEQLTKVKECYSPLLYESQQLLIPLEELEKQMTSFYDSLGKINEIITVLEREAQSSALFKQKHQELLACQENCKKTLTLIEKGSQSVQKFVTLSNVLKHFDQTRLQRQIADIHVAFQSMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEK-GDPEELLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLMPQ-EGSEKIIKEHRVFFSDKGPHHLCEKRLQLIEELCVKLPVRDPV----RDTPGTCHVTLKELRAAIDSTYRKLMEDPDKWKDYTSRFSEFSSWISTNETQLKGIKGEAIDTANHGEVKRAVEEIRNGVTKRGETLSWLKSRLKVLTEVSSENEAQKQGDELAKLSSSFKALVTLLSEVEKMLSNFGDCVQYKEIVKNSLEELISGSKEVQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQAQQGEGGLPDRGHE--ELRKLESTLDGLERSRERQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSS-----LESLSSELEQTKEFSKRTESIAVQAENLVKEASEIPLGPQNKQLLQQQAKSIKEQVKKLEDTLEEDIKTMEMVKTKWDHFGSNFETLSVWITEKE-KELNALETSSSAMDMQISQIKVTIQEIESKLSSIVGLEEEAQSFAQFVT-TGESARIKAKLTQIRRYGEELREHAQCLEGTILGHLSQQQKFEENLRKIQQSVSEFEDKLAVPIKICSSATETYKVLQEHMDLCQALESLSSAITAFSASARKVVNRDSCVQEAAALQQQYEDILRRAKERQTALENLLAHWQRLEKELSSFLTWLERGEAKASSPEMDISADRV-KVEGELQLIQALQNEVVSQASFYSKLLQLKESLFSVASKDDVKMMKLHLEQLDERWRDLPQIINKRINFLQSVVAEHQQFDELLLSFSVWIKLFLSELQTTSEISIMDHQVALTRHKDHAAEVESKKGELQSLQGHLAKLGSLGRAEDLHLLQGKAEDCFQLFEEASQVVERRQLALSHLAEFLQSHASLSGILRQLRQTVEATNSMNKNESDLIEKDLNDALQNAKALESAAVSLDGILSKAQYHLKIGSSEQRTSCRATADQLCGEVERIQNLLGTKQSEADALAVLKKAFQDQKEELLKSIEDIEERTDKERLKEPTRQALQQRLRVFNQLEDELNSHEHELCWLKDKAKQIAQKDVAFAPEVDREINRLEVTWDDTKRLIHENQGQCCGLIDLMREYQNLKSAVSKVLENASSVIVTRTT-IKDQEDLKWAFSKHETAKNKMNYKQKDLDNFTSKGKHLLSELKKIHSSDFS--LVKTDMESTVDKWLDVSEKLEENMDRLRVSLSIWDDVLSTRDEIEGWSNNCVPQMAENISNLDNHLRAEELLKEFESEVKNKALRLEELHSKVNDLKELTKNLETPPDLQFIEADLMQKLEHAKEITEVAKGTLKDFTAQSTQVEKFINDITTWFTKVEESLMNCAQNET-----CEALKKVKDIQKELQSQQSNISSTQENLNSLCRKYHSAELESLGRAMTGLIKKHEAVSQLCSKTQASLQESLEKHFSESMQEFQEWFLGAKAAAKESS-DRTGDSKVLEAKLHDLQNILDSVSDGQSKLDAVTQEGQTLYAHLSKQIVSSIQEQITKANEEFQAFLKQCLKDKQALQDCASELGSFEDQHRKLNLWIHEMEERFNTEN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LGESKQHIPEKKNEVHKVEMFLGELLAARESLDKLSQRGQLLSEEG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HGAGQEGRLCSQLLTSHQNLLRMTKEKLRSCQVALQEHEALEEALQSMWFWVKAIQDRLACAESTLGSKDTLEKRLSQIQDILLMKGEGEVKLNMAIGKGEQALRSSNKEGQRVIQTQLETLKEVWADIMSSSVHAQSTLESVISQWNDYVERKNQLEQWMESVDQKIEHPLQPQPGLKEKFVLLDHLQSILSEAEDHTRALHRLIAKSRELYEKTEDESFKDTAQEELKTQFNDIMTVAKEKMRKVEEIVKDHLMYLDAVHEFTDWLHSAKEELHRWSDMSGDSSATQKKLSKIKELIDS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------REIGASRLSRVESLAPEVKQNTTASGCELMHTEMQALRADWKQWEDSVFQTQSCLEN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVSQMALSEQEFSGQVAQLEQALEQFSALLKTWAQQLTLLEGKNTDEEIVECWHKGQEILDALQKAEPRTEDLKSQLNELCRFSRDLSTYSGKVSGLIKEYNCLCLQASKGCQNKEQILQQR----------------FRKAFRDFQQWLVNAKITTAKCFDIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QNISEVSTSLQKIQEFLSESENGQHKLNMMLSKGELLSTLLTKEKAKGIQAKVTAAKEDWKNFHSNLHQKESALENLKIQMKDFEVSAEPIQDWLSKTEKMVH-ESSNRLYDLPAKRREQQKLQSVLEEIHCYEPQLNRLKEKAQQLWEGQAASKSFRHRVSQLSSQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQDWMTDAIHMLDSYCHPTSDKSVLDSRTLKLEALLSVKQEKEIQMKMIVTRGESVLQNTSPEGIPTIQQQLQSVKDMWASLLSAGIRCKSQLEGALSKWTSYQDGVRQFSGWMDSMEANLNESERQ------------HAELRDKTTMLGKAKLLNEEVLSYSSLLETIEVKGAGMTEHYVTQLELQDLQERYRAIQERAKEAVTKSEKLVRLHQEYQRDLKAFEVWLGQEQEKLDQYSVLEGDAHTHETTLRDLQELQVHCAEGQALLNSVLHTREDVIPSGIP---QAEDRALESLRQDWQAYQHRLSETRTQFNNVVNKLRLMEQKFQQVDEWLKTAEEKVSPRTRRQSNRATKEIQLHQMKKWHEEVTAYRDEVEEVGARAQEILDESHVNSRMGCQATQLTSRYQALLLQVLEQIKFLEEEIQSLEESESSLSSYSDWYGSTHKNFKNVATKIDKVDTVMMGKKLKTLEVLLKDMEKGHSLLKSAREKGERAVKYLEEGEAERLRKEIHDHMEQLKELTSTVRKEHMTLEKGLHLAKEFSDKCKALTQWIAEYQEILHVPEEPKMELYEKKAQLSKYKSLQQTVLSHEPSVKSVRE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KGEALLELVQDVT------------------------------------------------------------------------------------------------------------------LKDKIDQLQSDYQDLCSIGKEHVFSLEAKVKDHEDYNSELQEVEKWLLQMSGRLVAPDLLETSSLETITQQLAHHKAMMEEIAGFEDRLNNLQMKGDTLIGQCADHLQAKLKQNVHAHLQGTKDSYSAICSTAQRMYQSLEHELQKHVSRQDTLQ----QCQAWLSAVQPDLEPSPQPPLSRAEAIKQVKHFRALQEQARTYLDLLCSMCDLSNASVKTTAKDIQQTEQTIEQKLVQA----------------------------------------------------QNLTQGWEEIKHLKSELWIYLQDADQQLQNMKR--RHSELELNIAQNMVSQVKDFVKKLQ----------------SKQASVNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRD-------YHDCMNVVEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQER-KYAIEDLKDQKQKMIEHLNLDDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIAEALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALSDAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHE-RKIMFREHICLLPDDVSKQVKTCKSAQASLKTYQN-EVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQKCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESSELHTQLAKYQNILEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQEAILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGEAVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQQLERQLKSVKEEQSKVN-EETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDPLAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELSGPVYLDLN-LQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLAELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESAEENLKSHMEFFSTEDQFH-SNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRDSGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKALVSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILEDAVDEWTGFNNKVKKATEMIDQLQDKLP--GSSAEKAS-KAELLTLLEYHDTFVLELEQQQSALGMLRQQTLSMLQDGAAPTP---GEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMVETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEK---MAEEQKEKYLGLYTILPSELSLQLAEVALDLK-IRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKLKAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLE--QNGQLGKPLAKKIGKLTELHQQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYILHQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQDAAKDMKKFEAELKKLQAALEQAQATLTSPEVGRLSLKEQLSHRQHLLSEM--------------------------------------------------------------------------------------------------------------------------------ESLKPKVQAVQLCQSALRIPEDVVASLPLCHAALRLQEEASRLQHTAIQQCNIMQ-----------EAVVQYEQYEQEMKHLQQLIEGAHREIEDKPVATSNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVEGLAEGTEDLDG---ELLPTPSAHPSVVMMTAGR-------------------CHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTDASVNQDIAYYQALSAERLQTDAAKIHPSTSASQEFYEPGLEPSATAKLGDLQRS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIELKLSESPEPGRS----------------------------------------------------------------------------------------------------------------------PESQMAEHQALMDEILMLQDEINELQSSLAEELVSE--SCEADPAEQLALQSTLTVLAERMSTIRMKAS-------------------GKRQLLEEKLNDQLEEQRQEQALQRYRCEADELDSWLLSTKATLDTALSPPK-EPMDMEAQLMDCQNMLVEIEQKVVALSELSVHNENLLLEGKAHTKDEAEQLAGKLRRLKGSLLELQRALHDK---------------------------------------------------QLNMQGTAQEKEESDVDLTATQSPGVQEWLAQARTTWTQQRQSSLQQQKELEQELAEQK-----------------------------------------------------------------------SLLRSVASRGEEILIQHSAAETSGDAGEKPDVLSQELGMEGEKSSAEDQMRMKWESLHQEFSTKQKLLQNVLEQEQEQVLYSRPNRLLSGVPLYKGDVPTQDKSAVTSLLDGLNQAFEEVSSQSGGAKRQSIHLEQKLYDG-----------------------------------------------------------------------------------------------------VSATSTWLDDVEERLFVATALLPEETETCLFN---------QEILAKDIKEMSEEMDKNKNLFS--QAFPENG------------------------------------------------------------------------------------------------------------------------------------------------------------------DNRDVIEDTLGCLLGRLSLLDSVVNQRCHQMKERLQQILN--------------------------------------FQNDLKVLFTSLADNKYIILQKLANVFEQPVAEQIEAIQQAEDGLKEFDAGIIELKRRGDKLQVEQ------------------------------------------PSMQELSKLQDMYDELMMIIGSRRSGLNQNLTLKSQYERALQDLADLLETG-----------------------------------------------------------QEKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMILTETLFRKIISFAVQKETQFHTELMAQASAVLKRAHKRGVELEYILETWSHLDEDQQELSRQLEVVESSIPSVGLVEENEDRLIDRITLYQHLKSSLNEYQPKLYQVLDDGKRLLISISCSDLESQLNQLGECWLSNTNKMSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTVPQELEMVRDHLNAFLEFSKEVDAQSSLKSSVLSTGNQLLRLKKVDTATLRSELSRIDSQWTDLLTNIPAVQEKLHQLQMDKLPSRHAISEVMSWISLMENVIQKDEDNIKNSIGYKAIHEYLQKYKGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQGLVTEKIQLLEGLLESWSEYENNVQCLKTWFETQEKRLKQQHRIGDQASVQNALKDCQDLEDLIKAKEKEVEKIEQNGLALIQNKKEDVSSIVMS-TLRELGQTWANLDHMVGQLKILLKSVLDQWSSHKVAFDKINSYLMEARYSLSRFRLLTGS-LEAVQVQVDNLQNLQDDLEKQERSLQKFGSITNQLLKECHPPVTETLTNTLKEVNMRWNNLLEEIAEQLQSSKALLQLWQRYKDYSKQCASTVQQQEDRTNELLKAATNKDIADDEVATWIQDCNDLLKGLGTVKDSLFFLHELGEQLKQQVDASAASAIQSDQLSLSQHLCALEQALCKQQTSLQAGVLDYETFAKSLEALEAWIVEAEEILQGQDPSHSSDLSTIQERMEELKGQMLKFSSMAPDLDRLNELG----YRLPLNDKEIKRMQNLNRHWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLLEQQRAHELFQAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWLVEVSYLPMSGLGSVPIPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKWKSASMRLEEQK---KKLAFLLKDWEKCEKGIADSLEKLRTFKKKLSQSLPDHHEELHAEQMRCKELENAVGSWTDDLTQLSLLKDTLSAYISADDISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAIAQENK-----IQLQQMGERLAKASHESKASEIEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTVAKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHKKLIRLPLPD-DEHDLSDRELELEDSAALSDLHWHDRSADSLLSPQPSSNLSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAMSRALPSEDEEGQDDKDFYLRGAVGLSGDHSALESQIRQLGKALDDSR--------FQIQQTENIIRSKTPTGPELDTSYKGYMKLLGECSSSIDSVKRLEHKLKEEEESLPGFVNLHS--TETQTAGVIDRWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLCSPEFTQA--DSKESRDLQDRLSQMNGRWDRVCSLLEEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMQIKHELLESQLRVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTPRGKCSLSQPGPSVSSPHSRSTKG-GSDSSLSEPGPGRSG------RGFLFRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPMLRYTNGPPPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZWR6-1", "uniprot_id": "SYNE1_MOUSE", "id": "Q6ZWR6-1", "name": "Nesprin-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATSRASSRSHRDITNVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGIKLLALLEVLSGQKLPCEQGHRVKRIHAVANIGTALKFLEGRK-------IKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSMVSTETASPPSKRKVAAKIQGNAKKTLLKWVQHTAGKQMGIEVKDFGKSWRTGLAFHSVIHAIQPELVDLEKVKTRSNRENLEDAFTIAETQLGIPRLLDPEDVDVDKPDEKSIMTYVAQFLTQYPDIHGAGCDGQEDDVVFVGFTNNIALLLGFQRDDRLILKETKVWIEQFERDFTRAQMTESSLQDKYQAFKHFRVQYEMKRKQVEHIIQPLQRDGKLTLDQALVKQCWERVSSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALREEITIQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYQTRSVNGIPMPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVELLLQSYISFIENSKFFEQYEVTYQILKQTADIYVKAEGS-VEEAENVMKFMSEATAQWRNLSVEVRSVRSMLEEVISNWDRYGDTVASLQAWLEDAEKMLSQSEHAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEIVSRDLKQQLLLLNGRWRELFMEVKQYARADEMDRMKKEYIDVTTTLFGFATEAHRKLSEPLEVSFIN-VKLLIQDLEDLEKRVPVMDAQYKMIAKKAHLFAKESPQEEANEMLTTMSKLKEQLSKVKECCSPLLYEAQQLTVPLEELETQITSFYDSLGKINEILSVLEQEAQSSTLFKQKHQELLASQENCKKSLTLIEKGSQSVQKLVTSSQARKPWDHTKLQKQIADVHHAFQSMIKKTGDWKKHVEANSRLMKKFEESRAELEKVLRVAQEGLEEK-GDPEELLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIAVEKDRFSAAVEECRAELEQETKLAPQ-EGSEKIIKEHRVFFSDKGPHHLCEKRLQLIEELCGKLPVQDPV----RDTCGACHTALKELKASIDNTYTMLVDDPDKWKDYTSRFSEFSSWVSAKKACLKKIKDEPIDTGNHDEVKHMVDEIRNDITKKGESLSWLKSRLKYLIDISSENEAQKRGDELAELSSSFKALVALLSEVEKLLSNFGECVQYKEIVKSSLEGLISGPQESKEEAEMILDSKNLLEAQQLLLHHQQKTKMISAKKRDLQEQMEQAQQG--GQAGPGQE--ELRKLESTLTGLEQSRERQERRIQVSLRKWERFETNKETVVRYLFQTGSSHERFLSFSS-----LESLSSELEQTKEFSKRTESIATQAENLVKEAAELPLGPRNKRVLQRQAKSIKEQVTTLEDTLEEDIKTMEMVKSKWDHFGSNFETLSIWILEKE-NELSSLEASASAADVQISQIKVTIQEIESKIDSIVGLEEEAQSFAQFVT-TGESARIKAKLTQIRRYWEELQEHARGLEGTILGHLSQQQKFEENLRKIRQSVSEFAERLADPIKICSSAAETYKVLQEHMDLCQAVESLSSTVTMFSASAQKAVNRESCTQEAAALQQQYEEILHKAKEMQTALEDLLARWQRLEKGLSPFLTWLERCEAIASSPEKDISADRG-KVESELQLIQALQNEVVSQASLYSNLLQLKEALFSVASKEDVAVMKLQLEQLDERWGDLPQIISKRMHFLQSVLAEHKQFDELLFSFSVWIKQFLGELQRTSEINLRDHQVALTRHKDHAAEIEKKRGEITHLQGHLSQLRSLGRAQDLHPLQSKVDDCFQLFEEASQVVERRKLALAQLAEFLQSHACMSTLLYQLRQTVEATKSMSKKQSDSLKTDLHSAIQDVKTLESSAISLDGTLTKAQCHLKSASPEERTSCRATTDQLSLEVERIQNLLGTKQSEADALVALKEAFREQKEELLRSIEDIEERMDRERLKVPTRQALQHRLRVFNQLEDELNSHEHELCWLKDKAKQIAQKDVAFAPEVDREINGLEATWDDTRRQIHENQGQCCGLIDLVREYQSLKSTVCNVLEDASNVVVMRAT-IKDQGDLKWAFSKHETSRNEMNSKQKELDSFTSKGKHLLSELKKIHSGDFS--LVKTDMESTLDKWLDVSERIEENMDMLRVSLSIWDDVLSRKDEIEGWSNSSLPKLAENISNLNNSLRAEELLKELESEVKIKALKLEDLHSKINNLKELTKNPETPTELQFIEADLRQKLEHAKEITEEARGTLKDFTAQRTQVERFVKDITAWLINVEESLTRCAQTET-----CEGLKKAKDIRKELQSQQNSITSTQEELNSLCRKHHSVELESLGRAMTGLIKKHEATSQLCSQTQARIQDSLEKHFSGSMKEFQEWFLGAKAAARESS-NLTGDSQILEARLHNLQGVLDSLSDGQSKLDVVTQEGQTLYAHLPKQIVSSIQEQITKANEEFQAFLKQCLKEKQALQDCVSELGSFEDQHRKLNLWIHEMEERLKTEN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LGESKHHISEKKNEVRKVEMFLGELLAARESLDKLSQRGQLLSEES---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HSAGKGGCRSTQLLTSYQSLLRVTKEKLRSCQLALKEHEALEEATQSMWARVKDVQDRLACAESTLGNKETLEGRLSQIQDILLMKGEGEVKLNLAIGKGDQALRSSNKEGQQAIQDQLEMLKKAWAEAMNSAVHAQSTLESVIDQWNDYLEKKSQLEQWMESVDQRLEHPLQLQPGLKEKFSLLDHFQSIVSEAEDHTGALQQLAAKSRELYQKTQDESFKEAGQEELRTQFQDIMTVAKEKMRTVEDLVKDHLMYLDAVQEFADWLHSAKEELHRWSDTSGDPSATQKKLLKIKELIDS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------REIGAGRLSRVESLAPAVKQNTAASGCELLNSEMQALRADWRQWEDCLFQTQSSLES---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVSEMALSEQEFFGQVTQLEQALEQFCTLLKTWAQQLTLLEGKNSDEEILECWHKGREILDALQKAEPMTEDLKSQLNELCRFSRDLSPYSEKVSGLIKEYNCLCLQASKGCQNKEQILQER----------------FQKASRGFQQWLVNAKITTAKCFDLP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QNLSEVSSSLQKIQEFLSESENGQHKLNTMLFKGELLSSLLTEEKAQAVQAKVLTAKEEWKSFHANLHQKESALENLKIQMKDFEVSAELVQNWLSKTERLVQ-ESSNRLYDLPAKRREQQKLQSVLEEIQCYEPQLHRLKEKARQLWEGQAASKSFVHRVSQLSSQYLALSNVTKEKVSRLDRIIAEHNRFSQGVKELQDWMSDAVHMLDSYCLPTSDKSVLDSRMLKLEALLSVRQEKEIQMKMVVTRGEYVLQSTSLEGSAAVQQQLQAVKDMWESLLSAAIRCKSQLEGALSKWTSYQDDVRQFSSWMDSVEVSLTESEKQ------------HTELREKITALGKAKLLNEEVLSHSSLLETIEVKRAAMTEHYVTQLELQDLQERHQALKEKAKEAVTKLEKLVRLHQEYQRDLKAFESWLEQEQEKLDRCSVHEGDTNAHETMLRDLQELQVRCAEGQALLNSVLHTREDVIPSGLP---QAEDRVLESLRQDWQVYQHRLAEARMQLNNVVNKLRLMEQKFQQADEWLKRMEEKINFRSECQSSRSDKEIQLLQLKKWHEDLSAHRDEVEEVGTRAQGILDETHISSRMGCQATQLTSRYQALLLQVLEQIKFFEEELQCLEETESSLSSYSDWYGSTHKNFKNVATKIDKVDESMMGKKLKTLEVLLKDMEKGHSLLKSAREKGERAMKFLAEHEAEALRKEIHTYMEQLKNLTSTVRKECMSLEKGLHLAKEFSDKYKVLAQWMAEYQEILCTPEEPKMELYEKKAQLSKYKSLQQMVLSHEPSVTSVQE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KSEALLELVQDQS------------------------------------------------------------------------------------------------------------------LKDKIQKLQSDFQDLCSRAKERVFSLEAKVKDHEDYNTELQEVEKWLLQMSGRLVAPDLLEMSSLETITQQLAHHKAMMEEIAGFEDRLDNLKAKGDTLIGQCPEHLQAKQKQTVQAHLQGTKDSYSAICSTAQRVYRSLEYELQKHVSSQDTLQ----QCQAWISAVQPDLKPSPQPPLSRAEAVKQVKHFRALQEQARTYLDLLCSMCDLSNSSVKNTAKDIQQTEQLIEQRLVQA----------------------------------------------------QNLTQGWEEIKSLKAELWIYLQDADQQLQNMKR--RHTELEINIAQNMVMQVKDFIKQLQ----------------CKQVSVSTIVEKVDKLTKNQESPEHKEITHLNDQWQDLCLQSDKLCAQREQDLQRTSS-------YHDHMRVVEAFLEKFTTEWDSLARSNAESTAIHLEALKKLALALQEE-MYAIDDLKDCKQKLIEQLGLDDRELVREQTSHLEQRWFQLQDLVKRKIQVSVTNLEELNVIQSRFQELMEWAEEQQPNIVEALKQSPPPGMAQHLLMDHLAICSELEAKQVLLKSLMKDADRVMADLGLNERKVIQKALSEAQKHVSCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHE-RKIVFREYICLLPDDVSKQVKTCKTAQASLKTYQN-EVTGLCAQGRELMKGITKQEQEEVLGKLQELQTVYDTVLQKCSHRLQELEKSLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNEKTELHAQLDKYQSILEQSPEYENLLLTLQTTGQAMLPSLNEVDHSYLSEKLSALPQQFNVIVALAKDKFYKTQEAILARKEYTSLIELTTQSLGDLEDQFLKMRKMPSDLIVEESVSLQQSCSALLGEVVALGEAVNELNQKKESFRSTGQPWQPEKMLQLATLYHRLKRQAEQRVSFLEDTTSVYKEHAQMCRQLESQLEVVKREQAKVN-EETLPAEEKLKVYHSLAGSLQDSGILLKRVATHLEDLSPHLDPTAYEKAKSQVQSWQEELKQMTSDVGELVTECESRMVQSIDFQTEMSRSLDWLRRVKAELSGPVCLDLS-LQDIQEEIRKIQIHQEEVLSSLRIMSALSHKEQEKFTKAKELISADLEHTLAELQELDGDVQEALRTRQATLTEIYSRCQRYYQVFQAANDWLDDAQEMLQLAGNGLDVESAEENLRSHMEFFKTEGQFH-SNMEELRGLVARLDPLIKATGKEELAQKMASLEKRSQGIIQESHTQRDLLQRCMVQWQEYQKAREGVIELMNDAEKKLSEFAVLKTSSIHEAEEKLSKHKALVSVVDSFHEKIVALEEKASQLEQTGNDTSKATLSRSMTTVWQRWTRLRAVAQDQEKILEDAVDEWKRLSAKVKETTEVINQLQGRLP--GSSTEKAS-KAELMTLLESHDTYLMDLESQQLTLGVLQQRALSMLQDRAFPGT---EEEVPILRAITALQDQCLNMQEKVKNHGKLVKQELQEREAVETRINSVKSWVQETKDYLGNPTIEIDTQLEELKRLLAEATSHQESIEK---IAEEQKNKYLGLYTVLPSEISLQLAEVALDLK-IHDQIQEKVQEIEEGKAMSQEFSCKIQKVTKDLTTILTKLKAKTDDLVHAKAEHKMLGEELDGCNSKLMELDAAIQTFSE--RHSQLGQPLAKKIGKLTELHQQTIRQAENRLSKLNQALSHMEEYNEMLETVRKWIEKAKVLVHGNIAWNSASQLQEQYILHQTLLEESGEIDSDLEAMAEKVQHLANVYCTGKLSQQVTQFGREMEELRQAIRVRLRNLQDAAKDMKKFEGELRNLQVALEQAQTILTSPEVGRRSLKEQLCHRQHLLSEM--------------------------------------------------------------------------------------------------------------------------------ESLKPKMQAVQLCQSALRIPEDVVASLPLCHAALRLQEEASQLQHTAIQQCNIMQAKKHSLIFPPKEAVVQYEQYKQEMKHLQQLIEEAHREIEDKPVATSNIQELQAQISLHEELAQKIKGYQEQIDSLNSKCKMLTMKAKHATMLLTVTEVEGLAEGTEDLDR---ELHPTPSAHPSVVMMTAGR-------------------CHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTEAAVNQDIAYYQALSAEGLQTDAARIPPSAAVSQELYEPGLEPSATAKLGDLQRS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WETLKNVISEKQRTLYEVLERQQKYQDSLQSISTKMEAMEMKLGESLEPSRS----------------------------------------------------------------------------------------------------------------------PESQMAEHQALMDEVQMLQDEINGLQVSLAEELVAE--SQESDPAEQLALQSTLTVLAERMSTIRMKAA-------------------GKRQLLEEKLSDQLEEQRQEQALQRYRCEADELDHWLLNTKATLDVALGTSQ-EPMDMDAQLVDCQNMLVEIEQKVVALSQLSVHNENLLLEGKAHTKEEAEQLAVKLRLLKGSLGELQRALHDR---------------------------------------------------QLDMQGVTQEKEENDVDFTDTQSPGVQEWLAQARTTRTHQRQSSLQQQKEFEQELAEQK-----------------------------------------------------------------------SLLRSVASRGEEILTQHSTAEGSGGLGEKPDVLSQELGI------AEDQMRVKWESLHQEFSAKQKLLQNILEQEQEQVLYSSPNRLLSGVLPFRGEAQTQDKTSVTSLLDGLSQAFGEASSQSGGTDRQSIHLEQKLYDG-----------------------------------------------------------------------------------------------------VSATSTWLNDVEERLFVATAPLPEETEACLFN---------QEALAKDIKEMSEEMDKNKNLFS--QAFPEDS------------------------------------------------------------------------------------------------------------------------------------------------------------------DNRDVIEDTLGCLLGRLSLLDSVVDQRCHQMKERLQQILR--------------------------------------FQNDLKVLFTSLADSKYIILQKLANVFEQPIVEQMQAIQQAEEGLRDLEGGISELKRWADKLQVEQ------------------------------------------SAVQELSKLQDMYDELLMTVSSRRSSLHQNLALKSQYDKALQDLVDLLDTG-----------------------------------------------------------QEKMTGDQKIIVCSKEEIQQLLGKHKEYFQGLESHMILTEILFRKIVGFAAVKETQFHTDCMAQASAVLKQAHKRGVELEYILEMWSHLDENRQELSRQLEVIENSIPSVGLVEESEDRLVERTNLYQHLKSSLNEYQPKLYQALDDGKRLLMSVSCSELESQLNQLGEHWLSNTNKVSKELHRLETILKHWTRYQSEAAALNHWLQCAKDRLAFWTQQSVTVPQELEMVRDHLSAFLEFSKEVDAKSALKSSVTSTGNQLLRLKKVDTAALRAELSRMDSQWTDLLTGIPVVQEKLHQLQMDKLPSRHAISEVMSWISLMESVILKDEEDIRNAIGYKAIHEYLQKYKGFKIDLNCKQLTADFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQLLQGRVGEKIQMLEGLLESWSEYENSVQSLKAWFANQERKLKEQHLLGDRNSVENALKDCQELEDLIKAKEKEVEKIEQNGLALIQNKREEVSGSVMS-TLQELRQTWISLDRTVEQLKIQLTSALGQWSNHKAACDEINGHLMEARYSLSRFRLLTGS-SEAVQVQVDNLQNLHDELEKQEGGLQKFGSITNQLLKECHPPVAETLSSTLQEVNMRWNNLLEEIAEQLHSSKALLQLWQRYKDYSKQCASAIQRQEEQTSVLLKAATNKDIADDEVTKWIQDCNDLLKGLETVKDSLFILRELGEQLGQQVDVSAAAAIQCEQLCFSQRLGALEQALCKQQAVLQAGVVDYETFAKSLEALEVWMVEAEGILQGQDPTHSSDLSTIQERMEELKGQMLKFSSLAPDLDRLNELG----YRLPLNDKEIKRMQNLNRHWSLTSSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEHKLAVEISGNYQHLLEQQRAHELFQAEMFSRQQILHSIIVDGQNLLEQGQVDDREEFSLKLTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWLAEVSHLPLSGLGNIPVPLQQVRMLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELTDIQEKWKAASMHLEEQK---KKLAFLLKDWEKCERGIANSLEKLRMFKKRLSQPLPDHHEELHAEQMRCKELENAVGRWTDDLTELMLVRDALAVYLSAEDISMLKERVELLQRQWEELCHQVSLRRQQVSERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAVAQENK-----IQLQEMGERLAKASHESKASEIQYKLSRVKDRWQHLLDLMAARVKKLKETLVAVQQLDKNMGSLRTWLAHMESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLEVSERTAAFPSSSGVLYTVAKEELKKFEAFQRQVHESLTQLELINKQYRRLARENRTDSACSLRQMVHGGNQRWDDLQKRVTSILRRLKHFISQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAVIEEELDELRRYCQEVFGRVERYHKKLIRLPVRLPDDHDLSDRELDLEDSTALSDLRWQDPSADGMPSPQPSSNPSLSLPQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAS-RTLPSEDEEGEEDKEFYLRGAVGLSGDPSSLESQMRQLDKALDDSR--------FQIQQTANILRSKTPTGPDLDTSYKGYMKLLGECSGSIDSVRRLEHKLAEEE-SFPGFVNLNS--TETQTAGVIDRWELLQAQAMSKELRMKQNLQKWQQFNSDLNNIWAWLGETEEELDRLQHLALSTDIHTIESHIKKLKELQKAVDHRKAIILSINLCSSEFTQA--DSKESHDLQDRLSQMNGRWDRVCSLLEDWRGLLQDALMQCQEFHEMSHALLLMLENIDRRKNEIVPIDSTLDPETLQDHHKQLMQIKQELLKSQLRVASLQDMSRQLLVNAEGSDCLEAKEKVHVIGNRLKLLLKEVSHHIKDLEKLLDMSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKSPRGKCSLSQPGPSVSSPKSRSTRD-GSDSSRSDPRPERVG------RAFLFRILRAALPFQLLLLLLIGLTCLVPMSEKDYSCALSNNFARSFHPMLRYTNGPPPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PC75-1", "uniprot_id": "A0A8M9PC75_DANRE", "id": "A0A8M9PC75-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEVKGKVARRWEDVAAKKKSGNSLNLVQGVSQHLRDEQEAVQKRTFTKWINSHLAKRNPPLVVSDLFEDVKDGVMLLALLEVLSGHKLPCEQGRKLRRIHWVANVGRALKFLEGRRSAYRGSPIKLVNINTTDVVDGRPSIVLGLIWTIILYFQIEELTSHLPALQPQSSSNSSVESSNSTETSSPPVKRKPRLSFQGGAKRALLKWVQNTATKRMGLDVKDFGPSWRTGVAFHAVIFALRPHLVNMERVWRRGNRENLEEAFSLAERELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHHPDRQHTETGQQQEE----FYLAPRAIEEMLEKEQRKTLRELKAWADQMERDCAQAQRDGGSLTVRYQTFKRFRVQFEVQRRQVETCVQSTQKDGKLTADQALVKQAWERLCKRLLDWHLQLDSGLPHPLGEVGVWLHQAEEILREELIPQQAHDETAKAIHKKRLRDQEILRLLERHKQTLQLIHRDRCVNNMPIPTEQLQDMAERLHYISTSSHIHLSKLEFWESKYSMLAFLTLAESKLKSWIIKYGRLESMELLLQSYGTFVEGQQFFEKYESSHQSLLQAAELYIKADSS-VEG--VVKLFLREVCDQWRSLSVEVRSVRSMLEEVQCNWLRYNSCVASLQAWLEDAQGALRQPENTKREFFRNLPHWMDQHAAMNDAGNFLIETCDETVTRDVKHQLLLLNGRWRELFLKVKQYARLPETHNVR-----IHQDIQEFLDASINKLTSPLQVSLLD-VKAFMQDVEEIKHKLPAVEAQYKAAARSAQLLAKVHGG--GNKARSTIPTTEAHLHQLKEKCPLTLKECQALFPLLEELEKQISAFYQTAEDAGHIITQQHNQEMC--------QELQTQQQTCKRCVCAIERSYLALQRALCCAKSLHNFDTSLLQNRVTEIQTTAQALMQEALEWRQVAETNGSLMRRFEESRADLEKALRVGQACLKER-GDPDELFRKHNEFFGRLDQHILSAYLKACDDLTDIISEEDQKSLRDTVRRLHKQWKDIQAEAPAHLLRLRVETERRFVMATLQDCRVELKREDKALPA-AGSEKIIKEHRAYFRQKTPLSACEKRLKTMKHFCQELPENDRG----YQMLEGAKDHLLEVKGLVDQTHLRLQQHPDKWREWHVRFSKLSEWLIS---------------TQNGAENSSVQMQRRAIKAQSETLDWLKARLAVLEEISPESEAHMQRDALEKLSQQFFAALLSLSEAAGVAN--EASVKTEEELK---EEVNDDDLIQIQEHRQILNAESATEAKQLLLIHQQNLKTQQGKDMDVRCQGNFFKED---------------------------RAAQEKHLQVTVSSWQEFEAEREAIWQFICHVSPVLQRELIFSS-----LDNLKSERNNIQELHEQGYMFAVRAESLVKKAADIKLGPQNQSMLQDQAQSTKERLQEIQDSLRKIVTDLEMTHRWWQSFNRESEAFFSWVCDSK-SDLEASAQTSATLDEQIHSVQMLKEGLEEKMDIFSQLETEFKTFINFIT-PNETGRIQARLMQIGRYQEEFKNNMDQRETELQSSLKHTKQFAQDLAEVESLLKGLLEKLNVSITSCTSASTTYKTLHEHMDAAQRLQQLGPRLMSLSLGWRRLPDAGQLEETVAELQKSHKLHTQQATEKQSKLENLLTLWQRYERDLSLLQSWSNRCESLCNSDSPYLTTDHV-KLHSQLEMLQDMQSEVPSQESLLESLETRAESLYSSATEERTAELRDLHCNLEERWCSLSTNIPLRIQELQSHLAQLEQFSEVSLALTQWSENFLRHIQTTCKVSISDLQSADSKTKEDKTSLQTQGRSLEALQPHLDALSPSLAPKDLQHLQTRKEDCIQLFNEAQSLVEHRDQALLKLKDFYESYNKAKDSLQTIQQAVQERGSWDDSKVRDINQELAELAEELASLEVQAISLDIILNKAHFHLQ-GSEEERVSCRGLVDDVAMSVQVLQRSIGTKQSEAEALASMWSSFRGRKELLIESLAKLEDRANISWPTETNSQAFQQRLWLLKQLEEELEALQHSQLWLRERGTQLALRDPELAEEAQRDVTLVQSAWERIRRIVAEDHDLCANLLELCRDYQTLKTRIISVVERAHAITVSQSD-PHNPDDIQRALSRLEAVRPELAATKEDLNKLIGSGRCLTDVLKKLPEESIQSENVSAEMDAIVDQWLDISEKMDADINLYTHSLELWNDINKMANEIECWTAVSVSELSEGSVGLLSSLDMQERLSDFKLELDNKEDELKILQAKMTELQELLKTQHTHTELQVMATDLRKQISHAAEVYEQTRGMCEDFSSQRQQLQDLISQISEQLKTSEDSLAEFSTSSD-----PENFAKIKEVERSQKQLEVSLDLAGESLRALCRTYPTQHLTLIGDAISNLVKRSEEVTQRRSQILGLLQEALLQRFNEKAHAFHGWLSELRAEAEVCF-EQTGDAVAIFSKQEKLKTVLEEVAEGEKRLACVCVDGERLLLHLSKGGTGGVQEQLDSCQNALDMFVLECRQRLQSLEESAGLLNAYEARVVELSDWLQQLELRLKTDAP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LWGESEPAAPDCSEELTRVEEIHRELLMRRASLERLCQSSVTVRERE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TRAEN--SAAEEMLLNHEALLQEARTRLR----SLQDYQAFEEALRAVETWLKDVEIKLEKLESTEGNKKEVEEKLEQAQDILLMKGEGEVKLNMAAGKAELVIKTNGEVERGVICSKLQEAEDAWAALLLGAMSCHSRLEWTVSQWDLFVESRAQLQRWLEGVGLEVKGPLEPQLGLREKRKQLERLRLLSSDVEDHQGALCYLEESAAELYKRTGDPVFKEEEMVLLRAHFEDVKAAAEERVRLSEDVVHEHKTYMETTRELTDWLMVVGEELQQCSDPSGDSPTLSRKLTDVRELLERG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ACEGRERLRRVRLSAERAGRHTAAAGCELMDGEVAALARALHQWEGASLRARDALET---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AVAAATGAEREQTRLTAQLEGEMEKLEGQLKEWSDGLSCAERRNSGAAAVEGWTLAKGVLEGLQTAEVMEEKLKAQLNELCGFSSDLGPQSDRVSALIKLHNSLSLRASRECQNKEKLLEQR----------------FRSSLHDFRQWLVNANISTAKCFDSP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HSIQDASIALQRIQEFMSDKEQGQTRLSAVLTYGEQLSSVLAAERVEAIRTKANTAKDDWKSLMDSLQRRETALQVLQSQMQDFEASIEPLQDWLNRTEISVQ-ESSARLHDLPAKRLELSKLQTLLEEMRSRESELAGLRGRAHGLWDGQGAGKSFVHRVCQLAACYLALSNLIKEKVSRVERVVGEHQLFSQGLQELQNWVSESQQVLKTCRCPTSDKTVLITRMGQLEALLAACQGKEIQLKMLITRGESVQRNTSAEGVPVVRKQIQDLKDSWESLLSTSIQCKSQLEGALSHWTSYQEDVSQFECWMERVEESLGNSDKH------------YAEMRDKTANLGRAKLLYEEVLSHSSPLETIATKGSNMTEHTATQQEIQKLSERYTTIKDKAKAAVSKAEELVLLHQEYQRGLHMFEDWLEQEQSNLAVLSPLDEDVNALEDTLKELQMLQSHCPKGHNLLSSVLSSRERVIPWGAP---QIEDRALETAKTEWQGYQDRLAETKVQVEQALARVQQLEGLFQSLDQWLVDMELKVKVRSHRRSDVTAKETQLQHLKRWQTEAACRQAEVEGLSTLAQQVVEDAHVSGRISTRVTQLTARYHALLLQIQETLKQLQEEMQKITEAQNALRTFSDWLSTASKNFKIITERTEALDRITMEKKMKRLESLQGEMDQAHSLLKTLRESAELAVSFLDDPGASRLEREVQTGRSQLEELILGLREEHVTLERSIVLYKDFQERYKGQMQWLRETRALLSSTVEPKVELYQRKAQLAKYKAVEQTLLSRDSAVSFVVE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KGETLLTLLHSPS------------------------------------------------------------------------------------------------------------------ITDNMSRLQADYQELRGTARTHVQRLEAQVKKQEAYHKDLQEIERWLLQMSSRMVTPEPSSSGGLEAATQQLARHKAIMEEIAGFEERLATLKEKGEELLSGCSERLQPRLRQQIQNHQQGAKDSYSAICSTAQRVYQSLDRELQKHVSVRDTLQ----QCQTWLSNVQEEVQLPEHAPQCLQEALTQMKQDRTLQEQASTYLQLVCSTCDLSDEKVQETAAEIQQVKLQIEERMLES----------------------------------------------------QELTDNWREIKDLRSNLECHLLEAEQLLQNMLR--RPAELEPKVAQNQLDQAQDFIQEMR----------------ARQVDLTHLRERINRLTAGQESPELMEVGRLRCSWLDLGRQAAQLLEQKEEDLQRSGD-------YHDCICMVEELFDQLSKKWDQLARGDIESTAECLDALKKLSTDLQDQ-RCVLDDLRNNRHGILPRLSLEDRDLVKEQVGYLEQRWTQVESLVQQKIQDSALTLEELSQIEDRLREAQEWAELQQPSLSEALKTSPPPDLAQSFLFDHLSFCAELEAKEKLLAEAMTDASSLSSRLGLNERRKLQTLVEEAQVEVASLGTKAAQYRKSLSKVFTERTQFLQALDRAAEWIKKQE-QRALADDHVALLPNVLHKQVAACKNFTSSLRAYQV-ELTSLWVQGRDLVKDSTEEEKKETLHKLEELQVIFEASLQKSAEHLHHLEKALVIRKYFQMDLDRICEWLKQAEEATFPVIDLSGNDVNLQNQLAQYQQLLDHASEYENLLLIVQRAGQEILPTLNEVDHCYLDEKLNGLPQQYNDMLLLIREKRDWIQQVLLERREFESLIDITRKALKELQEKSDGLEMQSANQSLEEGERLHRSYEDLLKGLGNLFQGMKDLRCKTQDFLSMGQPYAHEVTGQLVYLHSSLNKQIECKIKVLRKTLKVLNDHRAAIEKMDCKITRLKEQLDRLESDIEADAMERLSTLYDLSKCLKEASTHSEGLKAQNDDLNQHFD---LETLKTQVIFREEQLITLKQRINKHREKCERDLKGCKDFQIEG--FFDWLKSLRDQLRRPLMFDEANVEIVQQEASSLSALQEEMKSRFRVLEDISNEEKQKYIHDQKSFPKLFETTLMDIPKLKEDLQQAFNTKQVALQSALSLFQRYHHSLQCIQQWFDDAGALLEQVLLEPDLEKISDHLKDLEDTTGREHAVR-LMIDEMQDLIPQMGDHLSPTVIKHICQHCDESHHKATEVFEQLKQHQDNLQRSITQWRSFQDETDDVIRQMNDIEKRMKELTTAKANSEQEAEDNLHLYQRIMPQVQGLEDALNCLKEKAAQFDQP---AIKDVTSQSVRSVSHRWSRMNSVARAQVKTLQDSAHNWRCIREKLEKMRAVCEDLHSRVP--DSMVEKASSMAALHSLLEYHDSFSREVERESSALTLLRHHVLNLFLHPHTTAPTILNSEKPSLLEIQSIQDKYDILLQQVCASRQQVQMELLEREEVVRELGLLKGWIQDTQGLLLSPTADLDNLLTDLEAAHGGMLSHRQNLEQ---IVDRQQMKYQDLHTILPSEINTQLAEVTLALSSAEDQVQAREREVQHSRGIKEDFNSRLKDMSKKVKLISLKLKQKAVDVEEAKEETETLFEELEECARALSELDVAVQEFGE--QNPLLAKQLSFSLSKLTELHAQTSRLAEERTTCLQKAERNFEEFNEMLTLTLNWTEKAETVVSTNLMWSPLSQMQEQIRTHQALLQEWQDLQGEFEGLVERVALLGEVVQTEMLHQQVSELSRHAEELQQGAKTRLLTLQDAAKDLTRLENDVKSLHQSIERVQETLASPDLARLSLREQLAQRQLLLSEM--------------------------------------------------------------------------------------------------------------------------------EGLKQQVQAMQMCQSALRLPEDVMAALPLCVTAQSLQHESSQLQHNTIQQCNILQ-----------EALVQYEQYEQEVKNLQRLIEEAHRVIQDRPVATGNIQELQTQIQHHEELALKIKGYQEQISALNSKCKMLTVKAKHATMLLTVSEVDGLSDGLEELEDEEDEMPKHPPTHPSVVMMTAGR-------------------CHTLLSPVTEESGEEGTNSEVSSPPACRSPSPGPNADTSQ-----------------GSGRAPLSRAPLQELYDPSMESAASANLDDLQRS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WETLKNVISEKQKSLYEALERQQHYQETLQSVSTKMESIETALNEGLEPSKS----------------------------------------------------------------------------------------------------------------------PESQMAAHQALMDEILMLQDEISALQACFSQELQLDEDSLEADAGDQLALQSTLTVLGERMATIHMKAS-------------------GKRQLLEERLNEQLEEQRQEQALQRYHSEAEELDNWLLSTRATLSSTLQPHP-QDMDMEEQLIDCQNMLLEIEQKVLCLSELSVHSESLLLEGKAGTRGDAEQLSLKLHSLKSSLLELQRILQDK---------------------------------------------------QTHIQGSLQEQEDTESDSSLSQSPNMMDWLSQARSTRNQQHQDTVQRQRELEEQLGEQK-----------------------------------------------------------------------KLLQSVASRGEEILSQRTTPNGENCPAEFP---NGEDGQWPACMSTKDQMRVRWENLSKDLKNKLQLSLNTMEQTPCNALYQPVS---SPCGVFRGEQLSQDIPSPRSLFEGFNQDLEDLPQTGGTDSKRSRDLQKALYQA-----------------------------------------------------------------------------------------------------VSSASTWLDNAENELASGPVLLSDDSEAHLVH---------LEGLNKEVKNVNEEVCKCRDVLGGRERLWVEG------------------------------------------------------------------------------------------------------------------------------------------------------------------RESDVVEEVFDGLEGRLKLLDTVLEQQCDGMKDKLQELTV--------------------------------------FQTELRLLLTALNDSKYQLLQKMNAAMDRPASKQLEILAEAEDSLREFEQKVSEIRSRGETLQPNQ------------------------------------------ICTQELLKLQDAYEELVEMVGSKRSGLNQSLVLKAQYERALQDLVDLVDTA-----------------------------------------------------------QDKMAADQKMKVGSVIEVQILLDKHKEFFQGLETHVVLTQAFFRQISGLVVQREVQSLEETVAQAQAVLKQAHKRGVELEGILEWWSRLVGDYQALYRQLETVESSIPSVGLVEETEDRLSDRIALYQRLKASLSERQQQLYKLLEDGKRLVLHVSCSELESQLTQLGDHWLSTTTKINKELHRLDSTLKHWIRYQSESAELSQWLSSALDRLEFWSTQSVTVPQELETVRDHLHAFLEFSKEVDAKTSLRASVQSQGNQLLRLKKVDTAALRANLAKVDTQWADLLTRIPVVQEKLHQLQMEKLPSRHAITELMSWISLMENVIQEDQQKIMGAVGSVVVQMYLQKYKGFQIDLSCKQLTVDFVNQSVLQISNQDVEGKRSDKTDFAERLGAMNRRWQILQGLVTEKIQVLEGLLESWLEYENMVQTLKTWFSVQEEKVKKKHRIEDVSSAQNALKDCQEMEVLVKEKEKELEKAEEKGCLLIQDKKGEAGSFIMD-TLKNLNQSWANLDHMIGQQTVSLRSVLEQWSLYKQAYEEIQGYLMEGRYTISCLHLLTGS-PEAVQVQVENLQSLQDELEKQESSLRKLGSITQQLLKECHQSVSDSLNTALGDVNLRWNTLLEQISDQLRRSKSLLQLWQHYKALHAQCSADIHKLEEQVEHLLKSATHRDITQQEVK-------GLMATEGSVESVLQQLDEFSEQLRQQVDPSAMTTFHTEHLSLTQRLAAVGHALQRQQSLIEVSTRDYERFSKELNSLSRWAEEAEKVLKEQDPVGSPEISFVQDHMDKLKTQLLKLSSLSPDLERLNELG----YQLPLNDNEIKRLQNLNRSWSSNSARTIERFSKLQALVLQRQTFLEKCDAWMSFLTQTEEKLAAEISGNYQSLLDQQREHELFQAEMFSRQQVLNSIVNDGHELLNQGQVKDRDDFGLKLALLSNQWQGVVRRAQQRRGIIDSLVRQWQRYTELIGKLRHWLHEVSLEPEDQQQGTTVALQQIRGMLDHIQLKERILQRQQGSYILTVEAGRQLLLWADARAEASLHTELTDVQERWRAINIRLDERK---KELLSLLRDWDQCEKGITASHEKLRDFKQKLSVPLPDHHEELHTEQIRCKELEASIEGWADDVAGLCILRESLSSGLSADDLTVLHERLILLQRQWEETCHQLCLRRQQVSERLNEWAVFNEKNKELCEWLTHMESKVSQNGDVSIEEMIEKLTKDCQEEISVVEENK-----CQLEQMGERLAQASHESKAAEIQYKLCKVNERWQHLLDLIAARVKKLRETLVAVQQLDKNMSSLRSWLAHIETELSRPIVYETCDSHEIQRKLNQQQDLQRDIEKHSTGVASVLNLCEVLLHDCDACATETECESIQQATRGLDRRWRNICAIAMERRLKIEETWRLWQKFLDDYSRFEEWLKVSERTAALPNSSGVLYIVAKEELKKFEAFQRQVQEFLTQLELINKQYRRLARENRTDSSCHLRQMVHDGNRRWDILQRRVAAILRRLKHFIGQREEFETARDVILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFKQEISLNNTKVESVFGQGEVLMEKTEPLDAAVIEEELDELQRYCREVFGRVDRYYRKLTRLPLTD-DECEGSDHEFESDD---LSDLQWGEDGAIQQASSRPSS----AANAPARTNGSGRDTPASVDSIPLEWDHDYDLEPMSHTMSAERVRQKDED--EDLLCMATAALTDVVIPESPEAYIKLTENTLRSSSGEAVRLLDTMLDSSRYSLQQTDGSMDAHDTSYMGYMRLMDDCRGSLNMVKRVEGELEEDEENLSGLSNPDN--TETQSTGVIERWELIQAQSGDLEHRQTEDLLLWQQITSDLEDMEAWLEEAEAELAELRGRDLSADIHTIEQRIRRLKDLQKAMDSHKSKVLSINLNSVTLVQS--DSDESKVLKAKLKEMNSRWDQLGKSLKDWRTALQDALMQCQEFHELSHGLLLWLENIDRRRNEIIPIASGLDRHTLRAHHRALKQIQRELTETEQKVDGLQELSGQLLVQAHGNECLEAQERVHVIANRLRLLLKAVETDLEMLEKELQDSGNRQDASLWSVTDETETSGSVSPVSEVSVSTKRQSLRGKCSVSDPGSSSRLRRHRLARGSGCDSSRSGSSGSQGGVAVVRCQPFLLRVLRAALPLQLLLLLIVGLTCLVPMTEQDYSCTLANNFARSFHPMLRYTNGPPPV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9MRD1-1", "uniprot_id": "MS300_DROME", "id": "M9MRD1-1", "name": "Muscle-specific protein 300 kDa", "aln": "MADSGGPGSKHMDPTTIDAGGGGAGAAGGDDVPPVPAVRRRRAHEQKSSREQVLEEEKSQQLETSTVTRTYMKTITTSLTTSSSSNVEEFILGEHAAGAAAAPSPNQQRLRQKVAQYEKVWSDGSSPVKRPAEQSSDELRLTDDQDEYDAENPFEIDVHEIERRLRQERQRGLAEAEAAKLAFQQVQLRHTTPPRRVEVTSDQVASPFNVTLRTTSRMSPGAEHGNVEEHLAPFNVTLRTTRRTKKKEFKELENFLEGERTVREVPSADGVRTIITSSMTSDGGYAEEKIYRHGEGYVSPRDSPSWSRSSYSSERSSVTPPRSVDLTAGGRRILIKLEQESELTEENQTRDETDLSFGRQEVAMATGNIDITVGGSNPRRRLYQQTTVQVGGGNRTSPQDSTPQRPRDLDLAGTTKTMLTSTPIGTKEQPQTGPKTLVSPAATCQLRGSSTEEPRKIVSHKTITSTTTKSTSSSTSATSSSSTSRKLIETSPVVVGKIAQIRTGKSNASDNDIDIDNDSDTEGRPASSIVIVSTPTRPTTPATASVSASAVTPSASISATAAHALSGIGTFSKSLRQDYQTLATQSGRSNESPSDQEYQEFQSTMASINYARSNSQYDSHIKEKREEQERVQKKTFTNWINSYLLKRVPPLRIDDLINDLRDGTKLIALLEVLSGERLPVEKGRVLRRPHFLSNANTALQFLASKR-------IKLVNINPADLVDGRPPVVLGLIWTIILYFQIEENSRNLEYLGHGIGGSVSSLDSVGNQKHG----DLKAEKWKQGARKTLLNWVTNALPKDSGVEVKDFGASWRDGVAFLALIDAIKANLVNLAELKKTSNRQRLETAFDVAESKLGIAKLLDAEDVDVPKPDEKSIMTYVAQFLHKYPEPKGASRDQ--------SHVQQEADELRRFLVEKTTEYEPMVMMSSFPRDFGEYLLARSEVDAHLAAYNRLKQLIESQSGFLQVSRQSWEEIN----------ELWQRLQYQMMYWLWLLDSELPGDFGTVGKWLAEAEKLLMDNDIPNAMNEETAAVISRKLEEHKLFFADLPRILAMFDNAKRSPVAQ--QIPLEQLRNMERRLQEVGPKAAERRIRLKFLEHKCCLIAFLNLVENKMRGWTGKYGHEEKVAQQLEQYKNFVSRNKIFQEFQKAFVDMQQVVEEYKRDGNVPRKEINDIDRFMYETEERWKRVSMELKCCQNSLEEVVNCWRSWNQLAPTCEEWLQLAEQKVNQSEDERLDFFQDIPVWKDKFDALASSANYLIASCEEPIAQQLRQRHGALSERFERLFANTKQYMHAGDIIRSRQEYKSGIEQLSRWLRGAESVLDQRQVLGNSEQVKEYGQQLQQLASEIDDNEELFKTISRNFQSLIQDLSRDEVDKMMKLLKQEKESLVRIRAQLPAKLHLFHQLQIQQESLEAGQKEIHQWLSEAEQLLGTHNLSGGRDAIN-EQLHKHKTYFSRTVYYRSMLESKNKVFQNLLKAVSSDDKIDTAPASQQMQQLNERFNYVIQNAQQWEQRLDSAAGGWSNFKDNERVVSEWLTQAESMLVEKHIESKTTIETQKYFFEQVNDRWMNDLVQSAQQLLTTLPAQEQPAVVHSVEQLQSRWKNVLSQAPLHLLKLEFRLDENAFYQSLKDVEKELQLEQQALNRNEDVDSILQRNQQFLLQQDVVPRLERCLQNMQRLAQAHRQQQPGDISLDQAYDNAKSQWQLLSNKLGDMRQTLQQIPAQWQGYHLKFNDMVDWMNGVDQSLKNIVNEVNTMEEFEKEKVVFQKICQDADNKREDMKWLVKTLDSLLSYATEDEANLEQKKLEDLIARYKNLIPTIEITMVKTEVFSKCYTYRREVH----EVVCLLSKVKDQTANIPAPDSLDRVNRLIEEQQYAINQLDHQRPHIMSMLQRGRDLIKDVHAPAFVNAEVKNLETGWNQAYTETSDKLQALKGTQAVWSEFVDQKNDIFSMLQTAETELRSLTPLQTDPKNVSQDLKSKRDLNVQLQQASHQLLPKLHALKSELAPLAA-PDKRPILEKEVTEVEKMFFNTMEHVKDRVGYLEDYSAKWNNYKTRLAELQEWANKVAPKNIEALQSEDLTPEERVVKVQAFKRILGDRMKQLDLLAADASELAPKEGNIAEAKRLKGEITKLQEVLSAINRNVDHQAQAVQEDLVNWQQFQAGLQQIKPAVEQSEVKVNNVVSKPISLEEAVAMQQNAQQFETQCQEQLDKLHGISNISHKMLCKTNAPDELDAMHSRWTAVHENAKQASAKLEKLVANWKSFDADAAKLEDWVGQGEQQMSRRPAVLNTPHIDKLEKELVKLKSFNNEISQQQAKLVTLGQNADQISLHLAPEGAAALKDRVNQMKGKLQKLSEATRGHINEVSDAIISRQDFNAKLVNFSNWMEQLRNQVTQVEEINPERVETSLHVIHALLQEHADKKPSFNAIYDEVKQLALGATPEESNALNDAYTALVVNYQNLETNMLQKKAALEKWTELLGWKNDTESHLNYLKHQLDKPEGPAAEELSKVIDEIDNLGQGIGYWKGQAKEID---ENPAIQLRDALSRRPLIATQIVNDVENKLENLKLRSQSQQQQIQQMTVRKDKFHALEHNFGQALQENRAKLDEILRQHPTLNNIDQIIADLVALNDALKYQADLKNRIHDEGSLLMREDIASMPAIQESLLIMDKNYDSLQNEIADRIQKYNLISQALREYADSKDKFSKELKKAEDLYNAIPQQPRDETELHQASEKTRKTMEQLRKSKLSLDELERRGNNVGKLFSAIGEPIPQ--EVPQEVTAAKQHWQDLHDKTAKNAHVYETEAVIWSQIEDAKKDLLPWLSETNQGLCDAADNSIEIEFGPMRLSKYRTELPSYQALKDSIVEKTNDLVKINKGAEIP-ALSALNKLLSEQFAEVNNNADRLSAITTSFNDQEQELRRRSKEAGERVSKLREQLIKCDDMSGDNNKIMERLQQCRALRGELDNSGNEIDNIKQKVDELRNLYPTFSESIIPKELNNVQKRYENVDLYAKKIESSLLQFLKKFHADKVGMLKRIIATQREKVAWCQPESSSDKYNLDVKKSSLQEVSKSIDDCKARHAETLKSLEMLKAVESPQNLAELTSDAELLRKDMQALQDSFDQIKGILDENVDLWSQYEQSNEQISNWLRDVEGRVKAETSSQVNLSEVPQKLQELSILQQDVLAHEPIINNLEQTSQQLIEKNPEARIGQFVTHLVQRYQAVSKALTSYIDKIRGAQLSNANFAKAAKDFNEWFGDAKIEFQELARMGSPGSSSATAQQLQTVKNYIKTFDNGQILLNNAVDIGEALYPVVSPDNRERIRADLRQMREKFDYLRDEANAFMQQVEGVLIQKTSIEESYTQVSHYLNESKAKVPTTDELYPTLATKKAALQNYKTQLQEITLHKNALKQLHDKAVTLCDDESERKTDESIQEYNTLSKKISDRITTVGNHVVKHEAYDQVLEKAQDWLNTIKSEAIDILNETTFEKEGAEEKLLVVENLLQHKPEGDSIFDTCHKLLETVLTQTHPSGHPALLKGFEEPKQSWEDFMTLCQDSLVKLKQLCSKWDEFDTIIEELDNWMKNVEAVVKNQNLKSTAEAKNAHLKQLQDISKDIERRGAAINELMDQGREIEGETDLNLKLSRLNTRYQTLKNLCKESIAKYVNYVKDHESFDKDFDSFKQNLQSSVDELAKTNEIVGDQSVLQDQQNKLREMSDKRILDSTLFEGLIDRGEKLYGHTSPEGREIIRQQLRALRTLWDNYTDDLNSATQKIDQCLLQFNEFSIAQDQLTKWLKDVDKAMQSHTEPKTTLQEKRAQLQNHKLLHQEITTHNVLVDNVCDKAQILVDQIKDNSLN-VYLTSIKQLFQSIVQKSDEILHNLDDCVQKHNELNNALSSAKTWISNEKAKLLECDDAYGEKADIKRKIETLGQLAQNKPQAMKIISDIRDLFEKVKATTSEKGNEVLDKEIEELETTMKSHFDDIEGIEGKQKDVLAQWDKFEKALEELTKWCRSAEAVFREQQLQSTLHEKVEQLEKYKIQRELILQKEKEIDAFGDAAHALLNNCGADRLKTLTTQITNRYQLLQVLSKEVVNRWSNLVDDHQFYQDKYNEVDLWLQPIESQMAKVLLDEPTQSSNILQVLLSEKEQAESLFAALNAAGEKALPETSTQGREKIRKDLRDIRDRWDKLDEGIRNLEKRQEAQGVQLSSYQDILNQTVNWLDQVEKLIHNENPASWTSAQEIRSKLYKYKATNQDINSHKRIVEAVNEKAAALLGSAAPANADEISKAVAEVNKRYDQVGQDCAKLVADLDGAFDVYQQFSELQKAQQDYQKNLWDRLTGYSDYSGNKAALQARLQKINEIQDALPEGVAKLKSLEDHIEQQASNIPARSKEVMARDLANLHADFEKFGASLSDVKSGLENRLQQWNDYEINLDRLITWLGEAENSLKNYNLKSSFEEKEEQLNGFQSLAQNLRQNEADFDKVKDDTSELVQSSGETRIAVNVQQVSSRFQSIQATAKEILKKCEQAVQDHGHFNDKYKQCADWLANAQARYDDCCDLSTVASRDDLLKKQVVIQELLAQQPTATQLLNSTVELGEKCYGSTATEGREAIRSQLDDLTFDQLFDNIAITARKIQDKIAKWSGFDEIADSLKSWLDETENALPADIELKTTLDEKRNKLQTYRDILNDINNHQVELGNLQEIAANLPEKTELVDQIIKDISDRFGKLQKRAQNYVERYEGIVSAHQQYSKAVMDAQEFIDATLNTVHYWGDLDLEQISLHTNLDRLKNLKASLADEFPRVDQVRALGEKVIPGTVDVGQVNIKSQIDTTQQEWESLLTTISSTIEAIEARLQHWSEYEQLRDQCLAWIRDTDNNLHAIDLKEDLPKKRAQLDALKALQGDVRAKELEVDNVTEKAQTLLKGPSSNRASGPELVTKYQQIFHKVKELNNRWQQYVTSHEDFDNAISDCSSWINEIKEKLDYCSDMSSMS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TPGPDNLSGEPHNIWFSATTSVDKTPIELSQALIMSESLQHYPGQQKLTQEPILISTKEAIGDRIKQLKQASPQQATPLSNVLHLATLSEQIKELPTEQRILEVNEGLKDLDVAIKNGDKTVIQTTVITVIEKVSTWLETIEYRVYLIRQNSNEGPSEEKLDNYNQLNDELSTIKQNVVQLERQLSKAEPEPQLLQCVDSLKEHVDAVEQVTQQNQVQDSNDLDKWHNFEVLLYNVSSVLADLQQSYDLLINQEYPLSAKLAQLDELEQQHEAAQQQLAHLCQNARAFQRDFPGKKMPQDVHNAFETSKNIANNIQAERERVLQLQSLAEEYEQTLKEFTKITVLADKLVESPIVSSSLEQLNNEVQKQRKFFVNLSHCRAMLESLEENIDSETREKHSELHKELYNRATSLLDKASERSSKLVQAASRWTVLEKGMRDELQWLQVAQQRVPDLSAVTSAD--YDQYTTLYQSLSNDISHHYVKMTQLSGIANKLQLLVQAPNLVEETNEALIVLLKLREEVALYLHRLLVFKEIWVQYEQQTDKLEAFVREAEQELRNIQIPSQPTHQPIEHMRQFWEIKARFELHNNVRTDTGLSFEKS---LQVIPLADEMLQRQFHAQLEDRWQAVAQAIELIQHNIVECLSSEDVPADEKLKMVERELQEIYLTMTSMKGVIKNE--EELCLYIERVQVLRTRVGFIGNELGRIGLQEPAIEPEKVGELFSLSHKISTQIAEELEGASVLR----DQLQAIQEGISNQRKHQAKISVILDECEAAER--------QGADVLEKAVADCQAAGEELVISWQEIMRIRQMLHTLPMRLKMSVSPVKLERDISQLQDDHAFLESKCTNIMAILRSRLAVWLRYERQLELVHGSVQETDFMMELIRVHGQVDYERLRKATERLEGLAGDLHNREQLIDELKGAAKPLIESCDVQIVEQIESAVQEAVVAWNDTSENLQQLRTRYQRAVELWDKYRNASAAVKNSIDQQMDAVKSLEQPLDALQHAKVCQDN-----------LTTQNDRILELRDIVAKIAADVGLDASALMQGELDALGQRLAECKDAITTLANVAETQDKERKELDKEVTLAKAYFNNVQQDISREAPQNPKES---EEQLAALRAHLQTLARTEEQLRQLKERHQNSEVAPSVASSDDDGILEVLALWQKIFQDTFQEYHRLSTRLARSQNSSEALRLWRQYLQHVQSFLSCAIPEDYSSLREQQQLCAIHQNLLISQQSVLSETPLES-------------ELSEQYKALTNLHNETLSRIMQRNGELERRVSGWNAYRQQLAALLDWLRQREAER-NALQLRYIHLKRVPHLKHRLDAMIQQLDQGEQQSKALQEQQQELARHCDDALATAMRMEQASIGQRISNLRAALKTWQGFLQRVTQLSESYEQRVNQLQQEFGAAQKLLDANSESLPTQPAAIEQLLGSLRAQRVQLGAQVSALESLTVTQEELKECISPHDMKTIRQRNWLLWQQHADLDYQLANLINSIEERLSLLSNYQIRYDRISQWLQRLEQRVEKDADVTAMTNPEQAAKQLEQQVNSELQLRDKEREWLLSTSRELLTLYSEPEVRSQVQQQSDSLIDRWQRLKYLAKQKATKIGELKMTLLRLEERIALIRAWLFEVESQLDKPLNFESYTPNVIEAKLKEHEQIQRSIEHHSSNVGEVLNLVEMLLNDADSWRTQVNTSGLAASAQNLEQRWKNVCSQSAERKARILTIWNLLQQLIKLTAEHKNWLGKQE-----SQIAGFERDQKSHSKHKLEERQMELRAKLEELESQSVNLR------------------------------QLEQIYAKLAMSAGVEPENIQKLTLPTKVMVSMWRQLTPRCHALLDAIDKDAKLMREFNNAQLEATNSLNAIQKALEQLPSAENQQTSKAEPKAVLQRLESLEKKLQDAQQHVQQADNLAQEAKTRTKQQPQLKQLLELVSAYTTLWQT------------------VQTRIVTLKTTWLTRAAQAAASLPVSEAANAAVQVNTLSQRKLR-------------QAQQMQRETSITAKDAYIMELQTAITECQN-------NLDELQRTVVDKTRKPGPQKIAKLLGNAQSSTELVKHLSHLLLTECKADDQAAEVDTVAELTLRFDTLQSQWKARQQHDQNASEVGRLTCPLCTQRNWQQIDNDLWRLEQWLQFAESTQKAQSAP--PSNIELLEDVTQDHREFLLDLESHKSIISSLNVVGDHLATHTLDTEKARQLRSRLEADNERWNNVCINATKWQGLLQTALMGNSEFHQTIGELVEWLQRTEQNIKASEPVDLTEERSVLETKFKKFKDLRAELERCEPRVVSLQDAADQLLRSVEGSEQQSQHTYERTLSR-----LTDLRLRLQSLRRLSGIYIVKLGAVLGYEGDNLG-----VPLHMLSSELLDNTTLSTSSMQAAAPNTENANNTDGGD-AVDGDVINTTVLARG------ARFLGRVARASLPIQALMLLLLGVATLVPHG-EDYTCMFSNTFARSLEPMLSYPHGPPPT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. ... . :. ::*** ***:***:****:* ** **: :.**::*::** *:********.:** *:*: ::* * ::* . **:** .:: *******.:*:.****.:****:*********** : :* * .. * . ..:. . . : .*:::**:** : * *::***** *** *:** ::* *::..**:: : .**:.** ** :** :***.:***.***** *************** ::*: : : . . :: * . ..: ** . ..: : :::::: * : :: *. .. . : *:*: ::: * **. ** :* :* ** .** * :: : ::*** .* :* ..: :: :. : .: :* :**.:* .*:: :...: : :::* * * ::::* *.*.*::.* ***: *.: *:.* .*:. .::*:::: :. : *..: * : . : : *: *. :*: :*:*::. :. **** * :.. ..: : **: *: : *.*. : :**:::* * ::. *: .:.*:** :*:* :::::::: *. *:..** :.*** : : . : : : : * . :. : ** *::::: .: : :* ::. : : : .: : : * ::: . * : * *.** . ::: . .:: . . :: : . :* .*. : . . * : ..:: ::: : ::::: :*.: :: . .*::.. :.: * .: * *: :.. :. :. ** ::::: :. :::.::* :. ::* .: .:*.:*:.:**:: .:** ***:*.. :. . :::: . **. * : . :.*::.:: :: :: *: *: ::.:. .: : .: : :.. * : * :*: : :*..: .*: : : .: . : * :.** * * . :.*.**: . . * .* : : :. . . . .. :: : :: * ... ..::*: :* : . : .: :: : : :: : *..* ::: : : . . . :.: :.*.*: : :: : : : . * .: : : * :: :*: :. . :: . : :.. : :* *: : . : * . .::.: : : :: .:: . : .::. : * : . : *: *::..: :: . . :..: : * : ::* .* ::. :. :: :. * : :: : :. : :* :: . : ::. ..*.: .: **.*:: *: : : : * : * . :.: : *:. :* :: ::.*: .* : .* : : : : . :: ::. : .*. ::: :.. : . ::*. . :: * : : .: . ::. : : : . : .: : .: * .:: : *: . ::: . : ::. ** : :: . * ::: :: . .: : :: . : : * .:* :. :*: . .. . .::: .:: :: ::*.: : :. . *: :. : .:: . . : : .. : ::: : : *:: *: . :::... : .* :..: :: :: :. : : : : *:* * . . :: * : . :: ::: * .: . :: .: .*:.: *. : . :. : . . * :: : ::* *: :: : . . :*.:: . .:: * :.: . . *.. . *: . : * .:* :: * . *. : * ::: .. : : . .*. * ::. .: . . .:.* . . * : : : :. . .. .: :.: * . : : : :..: *: * . .: . : : * : . . :: : : . . : :.* : : .*: : ..: : : : . . : * . . : .: .: :: : . : *:: .. . :* ::. *::::* *.::: .* . . : . : *: : :*.:* : . : : . .: :: * . : : ::::::::: :. :: .* :. *.:. :: : .: ::: : ... :: .:.: .. : * :*. . * . . . :: : *:: : : ** :*::.*. :: : : *:** *:. : : .: * : : .: * .: * :: :: *:.: :.* :: :: *:.* :: . *: :* . .* *: . .:*: : :* : * :* :. : .* . *:: :: * .:: . .:. **. : :::* : :. :* : *: *:: : : : . : : * . . : **: .:: . ::. : :.. *:* .. ... : ::::.: * .: . .*: : : . * * . . . ::* : ::... :*: :. :: ** : : : : : :: . : ::.::.: .::::: *: * : :: . * : :**.: : *: .. :** *. : .:: ::..:. : :: :. * * .. .. . ::: :*:: * . *: *: :.::: :*. :. .::. ::*:::: :.: :..* .* * ::: *: : : :: :..** : :.* :* .:. ::: :: * *:. .* *** * :*:.*... *:. *: * .* :: .: : : :: : * ::: : ::::*... :::: * : : : .:.::: : .:** * :: : :*. : * ** : :..* * * :: ::*: ** . .:* *...* * . . * : :: : : ::: *:. * ::: .: : : : : . :** * :. .. :.. *: * ::: : :: :. ** ::: . *:. ***::*:*** * :: :: . * : .. ..* .: :::. :: : *:: :: * :: .:. *: * * .: : * :..: . .::.:* :.. .* . : ::: . * :*: : . : . * :* :::* * *:: ::: : .:: * : : :.: ** *::. * :.:**: :.* . :: ** :: . : *: .**::*:****:* :::: : .. * :*: :*:*:: ** :: .* *: **: : . . : :. : :. :***.:: .*: :: . * .* *. . .***: : ::: . :* ::. . . : : :. : :: : * . *: : .:. .: :: . * :: : :: ...:..* *.: * : :*. : * : *: : :*:::: : . * .: : : :: : ... * . ** : :* : : : :. *:: : *: :: : .. * * *.. . * : *:::: : . :::*:. : :. * : *.** *::*: :: . :.:* * . : :. :..: : :*.: * .: . . .* *: . :: : ***: * . . : * * ::. : : : . *. . :. . :..: : :* . :: : . : * . : *:: :. . : :: :*.: *. :::* . :: *:*: ::: ::.:.: : *:. * ** *: .:.. .**:: : .* : . *. ** :*:.:*..: : .*: :. *: :**:*.:.*: *.:.:. : ::. : :: : : :: * : : * ::: : : . . :*: * . :* : . : ::. . . : : : * :: *.. ::. .:: : . :: : :::. .: :::. : :.: . : :. *: : :* : . : . : : : .: * :***: . :* : ::.* . . .::: * :. :. :.. : : :. : * : .* .: . :. :: * . . .* : . ::*..:* *: * * :.* . * .: .::: : :. ..: . . . : : : . *:: :*:.:*. : * :: : . . . :: . : *:. .. : ::::* .: : : .:. : : * : . : . *:: ...* : .:. *..:. .. ... . :: ::: . : * : *.:: . . . . : : :: : : : : *. :* : * * .:. :: :: : * . : : . :: *: :. . :* . ***:: ::: : * . . :: : ::.:..: : :..: : : ::: :: . * : : .*: : :.. * : * :: : .:.:*: *. ::: : .: .: :: .* .: . . .: . .: ::: : : ::. : .:. : :.: : .* . : ::: : .:. * **:*.:: : * .::.:: *:.: * *.: : .*::** : *::: ..*. ::.::: ** *.: * * : :.:* : :::: ::: :*: :: :**:.. *: : .: * : .. ..:: . . .: * ::: *: : :*:.: : : .::: * : .:*. *:: : : : .: ::* : ..:*:.* ** ... ::..:.* ..*. .: : : .: :*.:*.: * : :** ** :: : ::: : ::.:* :*. .. :* : * : :. * . : * * :** . .:.* : . *.:. .: : :* *. * . : :: .. :: ** * ::: :.*: . :: : : :.: . *:*. . : : * : :* * :: :. . :.* :::* :.* : :*. : :: * . :. : : ::*:. : . * : : : . : .::::.. ::: : *::* ::: ::. * . * : . . . * :. * : : :. : . : : : *. . . : :. . . : ..* : .. . .*: :. ::::* :.: : .. :. :::: : . : :: *. .:: * ::: : : : : :: .. : .*:. *. . *:. :.: *: . . :. : * * :* : : * :::: : :: * :. : ::. .. : : . * .**: *: *: . : * * *: *:: * *:*..* :.. . :. : * ::: : *::::* .*. : : : .:* . . :. : : :* ::*.:* :*. :* . *: * . : : *:. :. :*.:. * . : : *** *. .:.. :: : .::* : :...:* .: .: *. :: **** : * :*:.:: * :: * :.* * .. * :* :*:. .*. . :.:: *. . * : .* * :::: :* : * :*.:: : .: . . :::. : . . : : *::: : :: :. . :. . *. :.* * . .:: ::. . .:*: :::* :: :.. ::: :. : *. . ::*: *** : . :*: : .: * : ... :. : :* : *: : * * * * :: : ::. : * : :. ::: * :: .:.*:.* .:*.::* : :: . :: *::.*. : : : .:: :. : ** *:: : : ::**::*: :.: : .. * :. : :. : :. : * :: :: :*. .* : :: : .: *:* .*: :. : : : *.: . : :.: :. : * . : :::: *: :: .:: :* :*:* .: ..: . : :: *. * :.: :*.: : : *. * * .:* :.: *: *. :*. * :**: :.* ::*:*.:* . :. ::. : *:* : .: * **.* :: : *: * : * .** : . . : *:: : ..:: : : : : . * ::* .* :::: * :.: :: *. : :.: * ..::: . : . : : . * .** : :. : . : .. : * : :: * :*..*:. :.:* ** :* : :*:. :.: ***. : :. : ..:.:** ::*.:*.::.*: *: *: :::: : : *. * *: *. . :::: : : :***:* * :..*: * ::: :*::.:. :*:** .:*::* :*: ::: .. *: **::::::**.**:**:.*..**** *:**:*.*: *:.: ..: :::.*::**:*:*: : **: :* *.* *:::. :..::** .* .. :*. ... :*:* * ::: * :** . : * :: * :* . . * :..* *** * :: . * :: *:: ..:: : * * . : : : : : . .: : .::: :: .*. . . : : : * : : * *: : .* .. : .: . : : : :: : .:: .. : : .. . :. * : : :. : * : :: .. . : *: : . :*. . ***: .** : ** :* .::*. :* : ::: :: :*: : *:*: . :. *:.::: *: :*. * **:.: .*: ** *** . **: *: *:. ::. : *: : *. :.: : ::: ** . : :* .**: : *** ...*.: . : :.:.. *. : :: *.: : . *: * * :: ...*:. .... . . . *.. . * ** *: **:**:* *:**::*:: *** :**:* ::*.****:.*** *.:**** ", "identical_positions": 1079, "similar_positions": 3238, "identity": "8.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4173", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V672-1", "uniprot_id": "G3V672_RAT", "id": "G3V672-1", "name": "", "aln": "MTHGEELGSDVHPDSIVLTYLEGLLMHQAAGGSGTAVDKKSAGHSEEDQNFNLSGSAFPTCQSNGPTLSTQTYQGSGMLHLKKARLLQSSEDWNAAQRKRLSDSIVNLNVKKEALLVGMVDSVPKGKQDSTVLASLLQSFSSRLQTVALSQQIRQSLKEQGYALSHES-LKVEKDLRCYGVASSHLKTLLKKSKTKDQKSGTTLPDVTPNLIRDSFVESSPHHVGQSGTKVMSEPLSCAARLQAVASMVEKRASPAASPKPSVACSQLALLLSSEAHLQQYSREHALKTQSAHQAASERLAAMARLQENGQK--DMSSFQLSKGVSGHLDGQARTLPQSSKLAASKNNAAVFQNPMCGVPSSPKNTSYKNSLERNNIKQAANNSLLLHLLKSQTIPTPMN--GHSQHERGSSF-ESSTPTTIDEYSDNNPSFTDDSSGDESSYSNCVPIDLSCKHRTEKPETE----RPVSLENLTQSLLNTWDPKVPGVDIKEDQDTSTNSKLNSHQKVTLLQLLLGHKTEESVERNASPQEVHSDVTKFSPQNYTRTSVIESPSTNRTTPVSTPPLHTSSQGESPINLSQHSLVIKWNSPPYACSTPASKLTNTVTGHLMDLTKGKESQAEKPAPSEGAQNSATFSASKLLQNLAQCGMQSSVPGEEQRPSKQLLSGHTD------KPLGLIDRLNSPLLSNKANAAEENKAFSSQPAGPEPGLPGCEIENLLERRTVLQLLLGNSNKGKSEKKERAPALDEARQEHSERPGNEQILMVKIKSEPCDDFQTHNTNVHLNHDAKSTPFLGGTPTIQRSSAALPVSEDLKSEPASPQ-DFSFSKNGLLSRLLRQNQESYPADDQDKSHRNSELTPLESKNFCMVPKKRKLYTEPLENPFKKMKNSAVDNANNHGGPEVLYGSLLNQEELKFSRNDLDYKYSAGHSSASDGEHRSWARESKSFNVLKQLLLSENCVRDLSPHRSNSVTDNKKKGHKNNVPNSKPEFSISSLNGLMYGSPQPG---SCV-DHRTFSYPGMVKTPLSSPFPEHLGCVGSRPEPGLLNGCSVPVPGEKGPIKWVITDVEKNEYEKDSPRLTKTNPILYYMLQKGG-NSVTTQETQDKDIWGEPSSAESLSQVTVKEEMLPAAETKAAFFNLRSPYNSHMGNNASRPHSTNGEAYGPLGNVLTIKKECE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CBD1-1", "uniprot_id": "NRIP1_MOUSE", "id": "Q8CBD1-1", "name": "Nuclear receptor-interacting protein 1", "aln": "MTHGEELGSDVHQDSIVLTYLEGLLMHQAAGGSGTAINKKSAGHKEEDQNFNLSGSAFPSCQSNGPTVSTQTYQGSGMLHLKKARLLQSSEDWNAAKRKRLSDSIVNLNVKKEALLAGMVDSVPKGKQDSTLLASLLQSFSSRLQTVALSQQIRQSLKEQGYALSHES-LKVEKDLRCYGVASSHLKTLLKKSKTKDQKSGPTLPDVTPNLIRDSFVESSHPAVGQSGTKVMSEPLSCAARLQAVASMVEKRASPAASPKPSVACSQLALLLSSEAHLQQYSREHALKTQNAHQVASERLAAMARLQENGQK--DVGSSQLSKGVSGHLNGQARALP-ASKLVANKNNAATFQSPMGVVPSSPKNTSYKNSLERNNLKQAANNSLLLHLLKSQTIPTPMN--GHSQNERASSF-ESSTPTTIDEYSDNNPSFTDDSSGDESSYSNCVPIDLSCKHRIEKPEAE----RPVSLENLTQSLLNTWDPKIPGVDIKEDQDTSTNSKLNSHQKVTLLQLLLGHKSEETVERNASPQDIHSDGTKFSPQNYTRTSVIESPSTNRTTPVSTPPLYTASQAESPINLSQHSLVIKWNSPPYACSTPASKLTNTAPSHLMDLTKGKESQAEKPAPSEGAQNSATFSASKLLQNLAQCGLQSSGPGEEQRPCKQLLSGNPD------KPLGLIDRLNSPLLSNKTNAAEESKAFSSQPAGPEPGLPGCEIENLLERRTVLQLLLGNSSKGKNEKKEKTPARDEAPQEHSERAANEQILMVKIKSEPCDDFQTHNTNLPLNHDAKSAPFLGVTPAIHRSTAALPVSEDFKSEPASPQ-DFSFSKNGLLSRLLRQNQESYPADEQDKSHRNSELPTLESKNICMVPKKRKLYTEPLENPFKKMKNTAVDTANHHSGPEVLYGSLLHQEELKFSRNELDYKYPAGHSSASDGDHRSWARESKSFNVLKQLLLSENCVRDLSPHRSDSVPDTKKKGHKNNAPGSKPEFGISSLNGLMYSSPQPG---SCVTDHRTFSYPGMVKTPLSPPFPEHLGCVGSRPEPGLLNGCSVP--GEKGPIKWVIADMDKNEYEKDSPRLTKTNPILYYMLQKGGGNSVTTQETQDKDIWREPASAESLSQVTVKEELLPAAETKASFFNLRSPYNSHMGNNASRPHSTNGEVYGLLGNALTIKKESE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48552-1", "uniprot_id": "NRIP1_HUMAN", "id": "P48552-1", "name": "Nuclear receptor-interacting protein 1", "aln": "MTHGEELGSDVHQDSIVLTYLEGLLMHQAAGGSGTAVDKKSAGHNEEDQNFNISGSAFPTCQSNGPVLNTHTYQGSGMLHLKKARLLQSSEDWNAAKRKRLSDSIMNLNVKKEALLAGMVDSVPKGKQDSTLLASLLQSFSSRLQTVALSQQIRQSLKEQGYALSHDS-LKVEKDLRCYGVASSHLKTLLKKSKVKDQKPDTNLPDVTKNLIRDRFAES-PHHVGQSGTKVMSEPLSCAARLQAVASMVEKRASPATSPKPSVACSQLALLLSSEAHLQQYSREHALKTQNANQAASERLAAMARLQENGQK--DVGSYQLPKGMSSHLNGQARTSS--SKLMASKSSATVFQNPMGIIPSSPKNAGYKNSLERNNIKQAANNSLLLHLLKSQTIPKPMN--GHSHSERGSIFEESSTPTTIDEYSDNNPSFTDDSSGDESSYSNCVPIDLSCKHRTEKSESD----QPVSLDNFTQSLLNTWDPKVPDVDIKEDQDTSKNSKLNSHQKVTLLQLLLGHKNEENVEKNTSPQGVHNDVSKFNTQNYARTSVIESPSTNRTTPVSTPPLLTSSKAGSPINLSQHSLVIKWNSPPYVCSTQSEKLTNTASNHSMDLTKSKDPPGEKPAQNEGAQNSATFSASKLLQNLAQCGMQSSMSVEEQRPSKQLLTGNTD------KPIGMIDRLNSPLLSNKTNAVEENKAFSSQPTGPEPGLSGSEIENLLERRTVLQLLLGNPNKGKSEKKEKTPLRDESTQEHSERALSEQILMVKIKSEPCDDLQIPNTNVHLSHDAKSAPFLGMAPAVQRSAPALPVSEDFKSEPVSPQ-DFSFSKNGLLSRLLRQNQDSYLADDSDRSHRNNEMALLESKNLCMVPKKRKLYTEPLENPFKKMKNNIVDAANNHSAPEVLYGSLLNQEELKFSRNDLEFKYPAGHGSASESEHRSWARESKSFNVLKQLLLSENCVRDLSPHRSNSVADSKKKGHKNNVTNSKPEFSISSLNGLMYSSTQPS---SCM-DNRTFSYPGVVKTPVSPTFPEHLGCAGSRPESGLLNGCSMP--SEKGPIKWVITDAEKNEYEKDSPRLTKTNPILYYMLQKGG-NSVTSRETQDKDIWREASSAESVSQVTAKEELLPTAETKASFFNLRSPYNSHMGNNASRPHSANGEVYGLLGSVLTIKKESE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BGF6-1", "uniprot_id": "A0A8M2BGF6_DANRE", "id": "A0A8M2BGF6-1", "name": "", "aln": "MTHGVESGPETHQDSAALTYLEGLLMHPVNTGPAATATQRSEPVHNNEENANSVTRAFQLHNHGALSPEKGSPPSATSQHLKKARLLRSG-AWSEDSQKQSSTGVEVNGQRREHYKGGLDG---SGQGESTLLASLLQSFSSRLQSVALSQHISQSHKQLDRESSESAPVDPKETYQSYGTASGRLKSLMRKSKHQNHNTVPYCRQSNQNRGSD-----SPRSSQNSAQPTSSESMSCTERLKAVASMVRTRSSPAPSPKPSVACSQLALLLSSEAHLQQYSREQALKAQLTSRSASERLAAMATQQTQDNRPPSMGQPTTTPDMLSSLNAQNGTIP--PLVVNSSKSSPSLSSPSTRPPKE------RRPFDRHGRPPQNCSSLLLLLLNNHNSQQQLTRNGHLEEDCGILPSCASSLQSDSEFSNPDNSLTKDSS-DAESLSSCSPIDLSMKSRTSCQKFEPCYSLPPLMDKLTESLVNKWKPETSVPKVHEAVDLDASPDIKSQDKVTLMQLLLDRRNNEKVNKSSDHPGLRSD------------SVISCLTAGSLKRIGTP-------EDSRTQSPQDRQVASFSSVSPSYSFPSP----VAQSSPLDLCKSKAHSSEKMEP--------PFSASKLLQNLAQSGIKNLSPSPPPLHPHKLTSKRQSPVLELGKPQAFLNRLVTPAKQNSPPVLDE-----GSPKCEQSPASSLQIENLLEKRTVLQLLLGTASQKEKNSGHRVLEVTSRGMEKARVG------SAKCDSSNGPPLDPNIKKEPVEENLQSDRFNDGVYHLSRSSQHSPIAEVQDTIKSELCPTETAAKFGLLSQLLKQQNAIYHSSPHTRLVRN-TVKEEPMDFHSPIPKKRKLCIELAERLSSELCQPPEDVTSDNPASGTPELKGRGLEKLKED-----------EPLGSPGNKTPLSRESQGFNVLKQLLLSENCLKELSQPRGTPSPFIPQANCAANGNLTQSGFRQELSNLPWYPYSFSSGPK---------TTPTPVDTPVWANVSPKASPKPVKKEP-------------EGSPEETFSREERS--SPDSPPLTRSNPILYYMLQRGN-----------------------GQLRPEMRDQMQSPHCVMGDYEHRINSPVHRQFHSQREDSLNGSVEKW------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** * *.:.* ** .********** . *..:: ::* ::::* * ** : .. .. : .: ********:*. *. .:*: * .: . ::* *: . .*: :**:*************:*****:* ** *: . *..: :. :: :.**.**.:**:*::*** ::::. . : . * * :*. . **.:**: **:******..*:***.***************************:***:* : : ********* * :.:: .:.. . .: . *:.* : . . : ....:. :..* *.. :..::*:. .**** **:.:. :. ** . : . :*: : .*:*: : *:*.*** * .* *.* ***** * * . : : * ::::*:**:*.*.*: . .::* * . ...::*::****:****.::.:*.*::.:. ::.* ***.. ::. . :.** * : .*. * .:.* . * : .. . :** *.* .** .************.*::. . ::* : . . ** .:::** :* .*.. . :* ..* :. .. :******:*********...: :.:. .:. . *::. .* .*. :: .: :..: :* * . . : **: *::* .: . : :* ****:**:*:: * :. : ** : . . :****** * *. .:: : * :..: .. . . *:** . . .* .:: . :***:.*************:::** *. . . : . * ::. * . * * . .. : * *.**: . .. : . : *. :*. : .:: ::. . *** **::*********:*. . . .: : :.. . :: * * ::.* .* **.. ", "identical_positions": 324, "similar_positions": 358, "identity": "27.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4174", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P02795-1", "uniprot_id": "MT2_HUMAN", "id": "P02795-1", "name": "Metallothionein-2", "aln": "MDPNCSCAAGDSCTCAGSCKCKECKCTSCKKSCCSCCPVGCAKCAQGCICKGASDKCSCCA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P02798-1", "uniprot_id": "MT2_MOUSE", "id": "P02798-1", "name": "Metallothionein-2", "aln": "MDPNCSCASDGSCSCAGACKCKQCKCTSCKKSCCSCCPVGCAKCSQGCICKEASDKCSCCA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7ZSY6-1", "uniprot_id": "MT2_DANRE", "id": "Q7ZSY6-1", "name": "Metallothionein-2", "aln": "MDP-CECAKTGTCNCGATCKCTNCQCTTCKKSCCSCCPSGCSKCASGCVCKGNSCGSSCCQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *.** .:*.*..:***.:*:**:********** **:**:.**:** * .*** ", "identical_positions": 36, "similar_positions": 16, "identity": "59.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-418", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUM4-1", "uniprot_id": "COR1C_MOUSE", "id": "Q9WUM4-1", "name": "Coronin-1C", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLT---------EPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADG-NVFTTGFSRMSERQLALWNPKNMQEP--IALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHER-KCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNAD-PILISLKH-------GYIPG---------------------KNRDLKVVKKNILDSKPAANKKSELSCAPKK----------------------------------------------------PTDTASVQNEAKLDEILKEIKSIKETICSQDERISKLEQQLAKMAA---------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V624-1", "uniprot_id": "G3V624_RAT", "id": "G3V624-1", "name": "Coronin", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLT---------EPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVRVIDPRRQEIVAEKEKAHEGARPMRAIFLADG-NVFTTGFSRMSERQLALWNPKNMQEP--IALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHER-KCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNAD-PILISLKH-------GYIPG---------------------KNRDLKVVKKNILDSKPAANKKSDLICAPKK----------------------------------------------------TTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQLAKMAA---------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ULV4-1", "uniprot_id": "COR1C_HUMAN", "id": "Q9ULV4-1", "name": "Coronin-1C", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLT---------EPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADG-NVFTTGFSRMSERQLALWNPKNMQEP--IALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHER-KCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNAD-PILISLKH-------GYIPG---------------------KNRDLKVVKKNILDSKPTANKKCDLISIPKK----------------------------------------------------TTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA---------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QEN6-1", "uniprot_id": "A0A8M9QEN6_DANRE", "id": "A0A8M9QEN6-1", "name": "Coronin", "aln": "MGQTQDKELQNEDVLTVGDYEILSESEEEAHSNSPEENFIQLDTSKLKIYPSQQPTRLNDNNTEPSFKRGGKKISNSYDTDVLQNARTPNPQLSLAGRPRASEFKTALSDATTTNISATEDQQRPDKADRMTNKTHLKDTPNMLESSCQGDTRDDAVSVVKNERRTMSERYNGMLEAVRKTSGEIHRKFSLQSEKDKLLESHPFQNVGDSERKDKGELQTLCRDIGKSNDKDSFGTVWPTESTDADGFEYLDRADSLHPVIVAKSPSVAGLHSYSGHASNQDNLQVDKNITPDTLMCILKEPNDTPKTHFTVTPKENLRKDQRNPTFHSPLLGKEETALPEWGETEGKDKILHTPFGESSLLRSKLTTLDSFDSDTVIECRNADTALVQLRIEEDFEQKALSTFHPDLSQSNAVFHTEKKNCDKGAFAVMEKHSTVLSSESLTESSAKKVCVSNAPHPAKNGLWGTDAPCVKRDSESVYPKAVQARSTEWRKDCDGPPNRRRNTSPLFELSGGNGKIQDVRLGKGVCDPKIYMLDDSNTEVKEILSNGKCLDQMIVNQFNSFSHSDLDATRVAQKASLQREKEPLYFTAVITPTCQIYTFPDQEDSQFYVPHSQIQNMMPDISAEDNQTDKKAKIKGPPPPVPKKPKNPFKKAAHLKESASHSVDEPREYSDLLLKNIKMGRRQAALQSVEDFSTHASCLDMLPYYMDSPSYMCMSVEPENADIPRYYLVPYDEIAPDYDNLIETADDEELKEMDMSQLRPILKKKAKRKGPPPPIPKKPQNPFVKTDTEQIRASKDSEFENVDLPLEYGRRDSESFMMDVEDEEDCKPTAALTRHLQAACSASEENDLSRFRPVSELIRDSNKIHEKVIHHSRTNIMEARPDVTAGCQNLKVSQMKQAFDVQTSSHKMERRSSPKKEMIRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSAFCAVNPKFVAIIVEASGGGAFLVLPLQKTGRIDKAYPTVCGHTGPVLDIDWCPHNDHVIASGSEDCTVMVWQIPENGLTSALS---------EPVVVLEGHSKRVGIVTWHPTARNVLLSAGCDNLIIIWNVGTGEALINLEDMHPDVIFSVCWSRNGSLICTACKDKKVRVIDPRKGKITAEKDKAHEGARPMRAIFLADG-NVFTTGFSRMSERQLALWNPKNMEEP--ISVHEMDTSNGVLLPFYDPDTNVVYLCGKGDSSIRYFEITDEAPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFYKLHER-KCEPIIMTVPRKSDLFQDDLYPDTAGPDPVLEAEEWFEGKNGE-PILISLKH-------GYVPG---------------------KNRDLKVVKKNVLDNK--ATKKVEEPTTPQKP---------------------------------------------------ASPQLTRKNEVKLEELLREVKSLRDLVTLQDRRIAKLEEQVSKVAI---------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KEJ7-1", "uniprot_id": "A0A0B4KEJ7_DROME", "id": "A0A0B4KEJ7-1", "name": "Coronin", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFRVVRSSKFRHVYGQALKREQCYDNIRVSKSSWDSTFCAVNPKFLAIIVESAGGGAFIVLPHNKVGRIAADHPLVGGHKGPVLDIAWCPHNDNVIASGSEDCVVKVWQIPDGGLSRTLT---------EPVVDLVFHQRRVGLVLWHPSALNVLLTAGSDNQVVIWNVGTGEILVHIDS-HPDIVYSACFNWDGSKLVTTCKDKKIRIYDPRTAELESEA-MCHEGSKATRAIFLRHG-LIFTTGFNRSSERQYSLRAPDALNEP--IVMVELDTSNGVMFPLYDADTNMIYLCGKGDSVIRYFEVTPEPPFVHYINTFQTTEPQRGIGLMPKRGCDVTTCEVAKFYRMNNNGLCQVISMTVPRKSDLFQEDLYPDTLAEDAAITAEEWIDGKDAD-PITFSLKDRVSIVQGGYVSSS--------------------VNKSLPAKKAGNILNKPRGDSASSGATSSSAGGGNFASGNNN-------------------------------------EASEGGPPAAVLSEKDLRTIQDEIRKLKAIIVKQENRIRALEAKEDARNKNGSDAAPASAG----------AATSDGKASESANDHASTSAGTSKDED---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06440-1", "uniprot_id": "CORO_YEAST", "id": "Q06440-1", "name": "Coronin-like protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGKFVRASKYRHVFGQAAKKELQYEKLKVTNNAWDSNLLKTNGKFIAVNWNASGGGAFAVIPIEEVGKAPDQVPLFRGHTAQVLDTDFDPFNDHRIASGSDDSKIGIWDIPENYKFHDHVDEDGEPIDIKPVKFLTGHARKVGHVLYHPVAENVLASSSGDYTVKLWNVETGKDMITLKH--PDMVTSMSFSYDGNYLATVARDKKLRVWNIREEKIVSEG-PAHTGAKNQRVVWLGNSDRLATTGFSKLSDRQIGIWDAFNIEKGDLGGFYTVDQSSGILMPFYDEGNKILYLVGKGDGNIRYYEFQNDE--LFELSEFQSTEAQRGFAVAPKRMVNVKENEVLKGFKTVVDQRIEPVSFFVPRRSEEFQEDIYPDAPSNKPALTAEEWFSGKSVEGPILVSMRSIYDGSAPSFHEAKRPQQPTTQETALEEKKEQPKVEKPISESEKEVKQEAPKSPSPLKSASSSSTINHVLKEDNSINKLLKKSSDIDQVNNAEDPSRDTSGWEEADDEPAPIKIETPVTPTETKKDRTPKVEPSKELKPEPVSIATDRKQEQSLPQEEKSSEKTKSPEQEKSATPPSSITAAKTAITASSKEEPSAARTSPKSLGLKKSVEKLSTLVLQLEDVVDKLTKANLDKDERLLKLEQKIGELSK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.** **:***:*** *.: *:.::*:. :*** : .* :*:*: :::***** *:* .:.*: * . **.. *** : *.**: *****:*. : :*:**:. :** * * ::** * :** * *** ::. * : :*** **: :: :. .*:: . .:. :*. : *..:***:*: : * :: :* .* *:: *.::* .. : ****.: *:** .: . ::: . :* *.*:::*:** ...::** ****. ***:*. : :. :. *.:.*.***:. *** :*. *: : :: : : : ***:*: **:*:***: . ...: ****:.**. : ** .*:: .: . :: : : . . . . .. : .. *:: : : .: * : ", "identical_positions": 131, "similar_positions": 165, "identity": "8.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4187", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TQ84-1", "uniprot_id": "UIF_RAT", "id": "Q7TQ84-1", "name": "UAP56-interacting factor", "aln": "MNRFGTRLVGATATTPPAPKARSNENLDKIDMSLDEIIKLNRKE------------GKKQSFPRLNRR-LQQSG----ARQLR----MR-VRWGVQQSS-GFGKTSVSRRGRVLPGKRRPYGVITGLAARKATGIRKGISP-MNRPPLSDKN--------IERYFPALKRKTSLLRQNEVQRK------PVAVLKRPNQLNRKNNIP-ANFTRSGNKLSHQKDTRQATFLFRRGLKVQT--QLNTEQLIDDVVAKRTRQWRTSTTNG-GILTVSIDNPGAVQCPVTQKPR-LTRTAVPSFLTKREQSDVKKIPKG----VPLQFDINSVGKQTGMTLNERFGILKEQRAALPFS-----KGGSRFVTVG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91Z49-1", "uniprot_id": "UIF_MOUSE", "id": "Q91Z49-1", "name": "UAP56-interacting factor", "aln": "MNRFGTRLVGATATPPPPPKARSNENLDKIDMSLDDIIKLNRKE------------GKKQNFPRLNRR-LQQSG----TRQFR----MR-VRWGIQQNS-GFGKTSLSRRGRVLPGKRRPYGVITGLAARKATGIRKGISP-MNRPPLSDKN--------IERYFPALKRKTSLLRQNEVQRK------QVAVLKRPNQLNRKNNIP-ANFTRNGNKLSHQKDTRQATFLFRRGLKVQT--QLNTEQLIDDVVAKRTRQWRTSTTNG-GILTVSIDNPGAVQCPVTQKPR-LTRTAVPSFLTKREQSDVKKVPKG----VPLQFDINSVGKQTGMTLNERFGILKEQRANLTFS-----KGGSRFVTVG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96QD9-1", "uniprot_id": "UIF_HUMAN", "id": "Q96QD9-1", "name": "UAP56-interacting factor", "aln": "MNRFGTRLVGATATSSPPPKARSNENLDKIDMSLDDIIKLNRKE------------GKKQNFPRLNRRLLQQSG----AQQFR----MR-VRWGIQQNS-GFGKTSLNRRGRVMPGKRRPNGVITGLAARKTTGIRKGISP-MNRPPLSDKN--------IEQYFPVLKRKANLLRQNEGQRK------PVAVLKRPSQLSRKNNIP-ANFTRSGNKLNHQKDTRQATFLFRRGLKVQA--QLNTEQLLDDVVAKRTRQWRTSTTNG-GILTVSIDNPGAVQCPVTQKPR-LTRTAVPSFLTKREQSDVKKVPKG----VPLQFDINSVGKQTGMTLNERFGILKEQRATLTYN-----KGGSRFVTVG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PK10-1", "uniprot_id": "A0A8M9PK10_DANRE", "id": "A0A8M9PK10-1", "name": "", "aln": "MVENEVQMKSTEDMQEPHASSS-----DKIDLSLDDIIKLNKKEQQANRAKTKRSANRNNILKKLNQVSLQQRGRRRGAQQYQGPGRMRGLRRGFRGSARGMSRGGSLNRATALTGEQFDQTSFTPRGTFRGRGRGRGRGGGLSRGALSARGQRGGRPFVLDRGFSATKRAEKLQKYQTINSRRTAPSGSMLTVSLPNAKSAPVAVTTSNQARRGGTVLRGRSSRGAGSASPKGIPLQFNYKATTNQTTVSLNDRFTGLWIRGRGRGQGRGAVGGEERGRGRGNFVRGGRGRGRGNFVGSGRGRGRGNFVGNGRGRGNFVGSGRGRGGENFARGGRGRGRGGTVVSGRGQGLIRGRGGLRGASRTVTLE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . .:: .: * ..: ****:***:*****:** .::: : :**: *** * ::* : ** :* *.: .: *:.: . .*. .:.*:: :* .: : * :* . :.* .** :. ::: *.. ** .* : : : : : .:. *. . :. :* :* *..: : :.:* * :*: :* : .*:* .: : * * . .* * :*. :: * : ..: * * . . * :.:. :* * . .. . * . * * : . *. :*.** **: ", "identical_positions": 70, "similar_positions": 113, "identity": "18.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-419", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K1A9-1", "uniprot_id": "A0A0G2K1A9_RAT", "id": "A0A0G2K1A9-1", "name": "", "aln": "MAALEEEFTLSTGVLG--AGPEGFLGVEPSDKADQFLVTDRGRTVVLYKVSDQKPLGSWSVKQGQTITCPAVCNFQTGEYIMVHDHKVLRIWNNEDVNLDKVFKATLSAEVHRIHSVQRTEPLVLFRRGAARGLEALLAEPQQNIEA-----VIPDEEVIEWSEVFMLFK-QPVLIFITENHGSYVAYVQLCKSHSLSKYILLLGKEEKSAKPNFTARVDGKFISLVSLGSDGCVYETLVPIYSSDTENN--QRLVRALMLKTVVSGSARNGSALTILDQDHIAVLGPPLPAS---KECLSIWNIKFQTLQTSKELPQGTSG-QLWYHGEILFMRHGKSLTVIPYKCEASSLASALGKLKHTQESGSHSVPHFVN---WETCSEYELGSYSAKQTR-TLR-KKTETNLHPEVPGVKELLSIIKKDSEKHIEVELRKFLA-KSTPDFHTIIGDIVSGLLGRCKVEPSFYPRNCLMQLIQTHVLSYS-LCPDLMEIALEHTDVQMLQLCLQQFPDIPESTTCACLKLFLSIGDDCLRDSNVSMESVFDYGDTTQDEKKEMEEQTEIVQNGFGPEDGGCSKDSQQLNKKPGDTAQEPISFPVTLCPVAPKRAALLRNAVLHSAYSEPFLLPHLKDIPAKHITLFLQYLYFLYLKCTGSATMTLPGVSPPTVS---QIMDWICLLLDANFTVVLMIPEAKRLLLNLYNFVKSQISIYSELNKIEVSFRELQRLNQEKSSRGLYS-----IEVLELF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJW5-1", "uniprot_id": "NOL11_MOUSE", "id": "Q8BJW5-1", "name": "Nucleolar protein 11", "aln": "MATLEEEFTLSTGVLG--AGPEGFLGVEQTDKADQFLVTDSGRTVVLYKVSDQKPLGSWSVKQGQSITCPAVCNFQTGEYIMVHDHKVLRIWNNDDVNVDKVFKATLSAEVHRIHSVQRTEPLVLFRGGAARGLEALLVEPQQNIES-----VIPDEEVIVWSEVFMLFK-QPVLIFITENHGHYYAYVRLCKSHSLSKYTLLLEKEEKSVKPNFTARVDGKFISLVSLSSDGCIYETLIPIYSSDTEQN--QRLVRALMLKSVVSGGVRNGVALTILDQDHIAVLGPPLSAS---KECLSIWNIKFQTLQTSKELPQGTSG-QLWYHGEVLFMLHGKSLTVIPYKCEESSLAGALGKLKHTQESGTHSVPHFVN---WETCSGYELGSSGAEQSR-TLRRKKVETNLQPEVPGFKQLLSIIKKDSEKHIEVELRKFLA-KSTPAFHTIIGDLVAGLVGRCKAEPSFYPRNCLTQLIQTHVLSYS-LCPDLMEIALEHTDVQMLQLCLQQFPDIPESTTCACLKLFLSVGDDCLRDSNINMESVFDYSDSTQDEKKEMEEQIEIVQNGFGPEDGNCSEDSQQLNDKPADTAHEPGSFPVTSCPVAPKRAALLN-AVLHSAYSEPFLLPHLKDIPAKHVTLFLQYLYFLYLKCTGSATMTLPGVNPPTVS---QIMDWICLLLDANFTVLLMIPEAKRLLLILYNFVKSQISIYSELNKIAVSFRELQRLNREKSSRGLYS-----IEVLELF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H8H0-1", "uniprot_id": "NOL11_HUMAN", "id": "Q9H8H0-1", "name": "Nucleolar protein 11", "aln": "MAALEEEFTLSSVVLS--AGPEGLLGVEQSDKTDQFLVTDSGRTVILYKVSDQKPLGSWSVKQGQIITCPAVCNFQTGEYVVVHDNKVLRIWNNEDVNLDKVFKATLSAEVYRILSVQGTEPLVLFKEGAVRGLEALLADPQQKIET-----VISDEEVIKWTKFFVVFR-HPVLIFITEKHGNYFAYVQMFNSRILTKYTLLLGQDENSVIKSFTASVDRKFISLMSLSSDGCIYETLIPIRPADPEKN--QSLVKSLLLKAVVSGNARNGVALTALDQDHVAVLGSPLAAS---KECLSVWNIKFQTLQTSKELPQGTSG-QLWYYGEHLFMLHGKSLTVIPYKCEVSSLAGALGKLKHSQDPGTHVVSHFVN---WETPQGCGLGFQNSEQSRRILRRRKIEVSLQPEVPPSKQLLSTIMKDSEKHIEVEVRKFLALKQTPDFHTVIGDTVTGLLERCKAEPSFYPRNCLMQLIQTHVLSYS-LCPDLMEIALKKKDVQLLQLCLQQFPDIPESVTCACLKIFLSIGDDSLQETDVNMESVFDYSINSVHDEK-MEEQTEILQNGFNPEEDKCNNCDQELNKKPQDETKES-----TSCPVVQKRAALLN-AILHSAYSETFLLPHLKDIPAQHITLFLKYLYFLYLKCSENATMTLPGIHPPTLN---QIMDWICLLLDANFTVVVMMPEAKRLLINLYKLVKSQISVYSELNKIEVSFRELQKLNQEKNNRGLYS-----IEVLELF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4V9P9-1", "uniprot_id": "NOL11_DANRE", "id": "Q4V9P9-1", "name": "Nucleolar protein 11-like", "aln": "MATLYEEYTLCGVGPDKNSSSSGILGIELGKDVDHIIVTNSSRAVTVYKVSDQKPTGSWTVKQGQLITCPAVYNTKSQEYVVVTDNKVIRVWKEDDVNMEKAFKATVSSDVLRVIAASDSEPVVLFSCGAVMFLDSLLASPQQTIEG-----VLTEEEFIRWSTVVGAEH-QLVLLFCTEKRGEHYLYAQRFNPNTVVKHRFETEPGPFAPIS-FSATCRGSNIHLQYLYMSGRIYESVLPLRSSVSEAEGVQALPRSLCLSLPLGEQELTSGAAIVLDEAHVAIVGFPHPSAGAGKDYLCIWNKHFQTLQACKELAGTIYS-QIWCYSGKLYIPHGKILSVISFECQKSSLAAAMGKLKQTNQSESKSHTPLSS---WTALPHNDSINAAKVKSR---MSTRNASNVKSPLT-VDQLIDHIKTAVVEDVQSAVGEFIHQTPQTDLQLAAGKVTMVLVSRSQTDDSFYPQRAFLQLLDTRYLCYS-VCPELLSLAMAKRDFQLCQIAFQLFPDIPEAVTCAYLKTILSTPDSEMETLTLDTESLIIMKEMSP-AQSQMEEGEQQNENGVSSSKQQRDFLSMDMK-----------------CPVGLHKGVLLN-DVLQTAYSDKPLLQHLKDLTVLQVMVFLQYLHFLYLKYSQDVHKQIRALRIPSIS---QVIDWASLILDAHFTVLAVAPEAKSLVSDLHKFTRSQVKLYAELGKIEGSLQSLKKP-KSTEHTGVYS-----IEVIELF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VW10-1", "uniprot_id": "Q9VW10_DROME", "id": "Q9VW10-1", "name": "", "aln": "MSKFLSYYNLFPIPDP-----KEFLGLAADRENGNVVTTLARNVVVVLNISTQKQLLSWSLP--EKLSSKVIYDPSSQKYVGVFGNHALRLWDVDTSDVSKCKKLKFQKSIAHVVAT-EQEALILYSDGECQTLSQALASRKDQKEDTAEQLALAASKVISKPTVHALAQGQQVLTYFEETKATGEMQLIRLSLDTADRRKYLIKREE-VRLTGYAVVEGDADPQLLTIWSDKRIFMLNLAEATSERSPG--------QFVSMLAELNVESKLSVHGVSRNFAAIYGANYGQE---GASLLVYNTQFKVVNAKQYFKVYLDFSRLWAGNEHILLAMGHNIAAVRYRMNREVLVDMLGSQFSDTHLSPIELDHINEEEYLESLIKFDGSTKPLNYRAVKSQLNKQMPNLDYQKADGRELAYDPPEVVDQEIDEIIKQHVHGEATICENGLEDVSVTLMTNFFDKGPNNTAVQALVRQLERSGAGEEEIIERILTLFIKTDNTEHVLMCLRRYSNISERMLAWSLRYALDKCKP--------------------------RHAINGDSNAVPTAKSYSNK-------------------------------ELLN-AVLACRFDATGIEEHLRYRLELSHVQHLMSHLFDLVNDPNVQLEERPSLNCSPIQTEVQAIQWFGCILTSHFTLLIIS-KDEALLETLSEWATFLSFYEESLFDLANLLPLLTNIVEKRQVKPMYSTNWYGIEEVVLY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : . :.* . :**: . .:.:.* ..* : ::* ** **:: : ::. .: : .: :*: * .::.:*:*. : ::.* * ... .: :: :. *.::*: * *. *.. :: * .:. .:.* . . : : ** : *.:. . : ::. * : . :: :. .: . :. . : :.. . *: * * ::* :*:.::: : : ::* . : : *: ::.: :. : . *. :*. . . : . : : .:. . :* :.:: : :.: : . . : . . . ..: : :: . : :: : : : : :.:: :.:*.* . *: *. . .. : .*.. . . . **. :* :. : **: .* * :: . .: ..:. * ::* :* ::**:: : : : *: * : . .* .: : * . .. . :** ** : *:", "identical_positions": 64, "similar_positions": 226, "identity": "8.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4194", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2X1-1", "uniprot_id": "FBX9_RAT", "id": "Q5U2X1-1", "name": "F-box only protein 9", "aln": "----------MAEAEEDCHSDAVRVGD-EGHESPAERDLQAQLQMFRAQWMFELTPGVGSSNVESRPCRAGRSSILKAAAD-KGRQELAKEEKARELFLKAVEEEQNGALYEAIKFYRRAMQLVPDIEFKITYTRSP-------------DGDGVGSSYIEDNEDASKMADLLSYFQQQLT-----FQESVLKLCQPELETSQTHISVLPMEVLMYIFRWV---VSSDLDLRSLEQLSLVCRGFYICARDPEIWRLACLKVWGRSCMKLVP--------FSSWR----EMFLERPRVRFDGVYISKTTYIRQGEQSLDG--FYRAWHQVEYYRYIRFFPDGHVMMLTTPEEPPSIVPRLRTRNTRTDAILLGHYRLSQDADNQTKVFAVITKKKEEKPLDH-KYRYFRRVPVQEADHNFHVGLQLCSSGHQRFNKLIWIHHSCHITYRSTGETAVSAFDIDKMYTPLFFARVRSYTAFSERPL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BK06-1", "uniprot_id": "FBX9_MOUSE", "id": "Q8BK06-1", "name": "F-box only protein 9", "aln": "---------MSAEAEEDCHSDADRVGD-EGNESPAERDLQAQLQMFRAQWMFELTPGVGSSHGETRPCRAGRSSMLKAAADTKGRQELAKEEKARELFLQAVEEEQNGALYEAIKFYRRAMQLVPDIEFKITYTRSP-------------DGDGVGSGYIEENEDASKMADLLSYFQQQLT-----LQESVLKLCQPELETSQTHISVLPMEVLMYIFRWV---VSSDLDLRSLEQLSLVCRGFYICARDPEIWRLACLKVWGRSCMKLVP--------YASWR----EMFLERPRVRFDGVYISKTTYIRQGEQSLDG--FYRAWHQVEYYRYMRFFPDGHVMMLTTPEEPPSIVPRLRTRNTRTDAILLGHYRLSQDADNQTKVFAVITKKKEEKPLDH-KYRYFRRVPVQEADHSFHVGLQLCSSGHQRFNKLIWIHHSCHITYKATGETAVSAFEIDKMYTPLLFARVRSYTAFSERPL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UK97-1", "uniprot_id": "FBX9_HUMAN", "id": "Q9UK97-1", "name": "F-box only protein 9", "aln": "MPDIIWVFPPQAEAEEDCHSDTVRADDDEENESPAETDLQAQLQMFRAQWMFELAPGVSSSNLENRPCRAARGSLQKTSADTKGKQEQAKEEKARELFLKAVEEEQNGALYEAIKFYRRAMQLVPDIEFKITYTRSP-------------DGDGVGNSYIEDNDDDSKMADLLSYFQQQLT-----FQESVLKLCQPELESSQIHISVLPMEVLMYIFRWV---VSSDLDLRSLEQLSLVCRGFYICARDPEIWRLACLKVWGRSCIKLVP--------YTSWR----EMFLERPRVRFDGVYISKTTYIRQGEQSLDG--FYRAWHQVEYYRYIRFFPDGHVMMLTTPEEPQSIVPRLRTRNTRTDAILLGHYRLSQDTDNQTKVFAVITKKKEEKPLDY-KYRYFRRVPVQEADQSFHVGLQLCSSGHQRFNKLIWIHHSCHITYKSTGETAVSAFEIDKMYTPLFFARVRSYTAFSERPL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P3K3-1", "uniprot_id": "FBX9_DANRE", "id": "Q6P3K3-1", "name": "F-box only protein 9", "aln": "----------MAESNQNTDGAVEEGED----ENTGDSNLQMELSAFRAKWMSELQPSSGGQRSFSR------------NAELRRRQETAKEEKARELFLKAVEEEQNGAVYEAIKYYKSAMQLVPDIEFKINYSRTP-------------DPE-RGGSYLESSENNREIDDLLTYFQHQLT-----LGNDAMKLCEHETETSQVHISALPFEVLMYIFRWV---VSCDLDLRALEQLSLVCRGFYICARDPEIWRSACLRVWGRSCTKMLP--------YSSWR----EMFLERPRVRFDGVYISKTSYIRQGEESLDG--FYRAWHQVEYYRYLRFFPDGQVMMLTTPEDPLVTVPRLRSKNSRMDSIMFGHYRLSQDTDNQTKVYVVVSKRKEEKVSEYQRSRFCRRNPVPEAERSFHVGLQLSSGGRQRFNKLVWIHHSCHITYRSTGETVVTAFDVDKMYTPLFFARVKSYTAFSERPL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VG61-1", "uniprot_id": "Q9VG61_DROME", "id": "Q9VG61-1", "name": "F-box only protein 9", "aln": "----------MSDVDSDGEEPTRKTGT-------------NALDEFRENWQRELQEHTTNTGSRSHSEAGDR----LTAANSNLSEADLLQAKAESLYRTAVQLEQRGKVYDALPFYRKATQIVPDIEFRFYEQQKQKLSNDVSKKYLNLANDLAKQLDLGQSDGEEVVDNLYEKFQHDLRQKNIYNGKMIASSRDANVLTTGLHFADLPPEIVMRILRWV---VSAQLDMRSLEQCAAVCKGFYVYARDEELWRLACVKVWGHNVGTLEAQDSDVSNVFHSWR----DMFIRRDRVLFNGCYISKTTYLRMGENSFQDQ-FYRPVQLVEYYRYIRFLPDGKVLMMTTADEPAQGVSKLKHVNNVRAEMLRGRYRLFG------STVTLVLQKSQQRGPANVRQRRGSIMPVDEDSSQFLIELRIAGTTKRRCAQLVWSHY-TLVQKRNKVDISSEFDLTEAKYPALRFSTVKSYHLDADAPLA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12347-1", "uniprot_id": "HRT3_YEAST", "id": "Q12347-1", "name": "F-box protein HRT3", "aln": "--------------------------------------------------------------------------------MIVDYEKDPRAKEAIAIWEKGVLKEKDGSMSDAINFYRSALKIHDNVESLYRKKILD--------------EWMLHKKLSGLSMTTDAPDEQNETGKDDLS---VEENAELQPCWILEILPDDILLRIIKKVILMSGESWVNLSMTCSTFSKLCFHDSVPFKTFAKYIYSKQIYDKMAMDLNGITDINTFEK--------EIWRGDDYRMLRERPYIKFEGVYISVVNYVRYGSNAESSLSLLKPVHMITYYRYFRFYENGQCLRLLSTDEPSAVVKHFSKENKPRHSHMCYWS------------------------LGFDYDFGHLKITRSDEKYTFIEEFQIKNQGNKRYQRLKWLSS---IVVDKEGNASNCSLRNEKS---FFFSRVKSFKDPG-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* :: .* *: * : :*: :*: * :: ::* . : :.:* : . : : ::* ** ::.. : : : : * . ::: .: : * . . ** *: .* : *:* *** ..*:* *.:: .. : :. : : ****:** :*: : : :.::* * :: *. : . : . * ::: . .:* :* * : : : : *: *:*: . ", "identical_positions": 43, "similar_positions": 91, "identity": "8.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4198", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NX78-1", "uniprot_id": "TM260_HUMAN", "id": "Q9NX78-1", "name": "Protein O-mannosyl-transferase TMEM260", "aln": "MSPHGDGRGQAQGRAVRVGLRRSGGIRGGVAVFAAVAAVFTFTLPPSVPGGDSGELITAAHELGVAHPPGYPLFTLVAKLAITLFPFGSIAYRVNLLCGLFGAVAASLLFFTVFRLSGSSAGGILAAGVFSFSRLTWQWSIAAEVFSLNNLFVGLLMALTVHFEEAATAKERSKVAKIGAFCCGLSLCNQHTIILYVLCIIPWILFQLLKKKELSLGSLLKLSLYFSAGLLPYVHLPISSYLNHARWTWGDQTTLQGFLTHFLREEYGTFSLAKSEIGSSMSEILLSQVTNMRTELSFNIQALAVCANICLATKDRQNPSLVWLFTGMFCIYSLFFAWRANLDISKPLFMGVVERFWMQSNAVVAVLAGIGLAAVVSETNRVLNSNGLQCL-EWLSATLFVVYQIYSNYSVCDQRTNYVIDKFAKNLLTSMPHDAIILLRGDLPGNSLRYMHYCEGLRPDISLVDQEMMTYEWYLPKMAKHLPGVNFPGNRWNPVEGILPSGMVTFNLYHFLEVNKQKETFVCIGIHEGDPTWKKNYSLWPWGSCDKLVPLEIVFNPEEWIKLTKSIYNWTEEYGRFDPSSWESVANEEMWQARMKTPFFIFNLAETAHMPSKVKAQLYAQAYDLYKEIVYLQKEHPVNWHKNYAIACERMLRLQARDADPEVLLSETIRHFRLYSQKAPNDPQQADILGALKHLRKELQSLRNRKNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BMD6-1", "uniprot_id": "TM260_MOUSE", "id": "Q8BMD6-1", "name": "Protein O-mannosyl-transferase TMEM260", "aln": "MGLHGDGGSPAAG----AGPWRSGALRGSVAVFASVAAVFTLTLPRSLPGGDSGELITAAHELGVAHPPGYPLFTLLASLTITLFPFGSVAYRVNLLCGLFGAVAASLLFYTVFRLSGSHAGGILAAGVFSFSRLTWQWSIAAEVFSLNNLFVGLLMALTVRFEEATAAKERSKIAAIGAFSCGLSLCNQHTIVLYILCIIPWILFRLLKEKELTLSLLLRLTLAFSAGLLPYVYLPVSSYLSRARWTWGDQTTLRGFLTHFFREEYGTFSLAKSEVGSSVSTVLLSQVINMKTELSFNIQALAVWANICLARKDRRKSSVVWLFTGMLCLYSLFFAWRANLDISKPLFMGVVERFWLQSNAVVAVLAGLGLATLVSETNRVLHCTGIRNL-EWLSAALFVAYQVYSNYSICDQRTNNVIDQFARNLLDSMPQDAIILLRGDLPGNALRYLHYCEGLRPDVSLVDQEMMTYEWYLPKMARHLPGVHFPGDRWNPVEGVLPSGMVTFNLYHFLEMNKQKETFVCIGIHEGDPTWKKDYSLWPWGSCDKLVPSKIVFNPEEWIERTRAIYNWTEAYERFGPSSWESVANEEMWQARMKTPFFIFSLAESAAVPADVKAQLYTHAYKLYKEIVYLQEEHPVNWHKNYAIACERMLRLPGTGIDPEVLLSEAIRHFHLYTQKAQNDPQRADIIAALKHLRRELQSLRNIKKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F5M2-1", "uniprot_id": "E7F5M2_DANRE", "id": "E7F5M2-1", "name": "", "aln": "MSSD----------------RWTWSLTG--ATVAGVSALYVGCAPRAVPGGDSGELITAACELGVAHPPGYPLFTMMSSLMLSLLPLSSPAHSINVLCAVFGAGASGALCFTVCRVAEPGPGAVLAGGVFAVSRLVWQWSVVAEVFSLNNLFVGVLFSLSACFHCADTVQQKKKFALWGALFCGLSLCNQHTLVLYVVVIIPWALLHLYTHNGLSFFDLVSLGTCFLAGFVPYMYLPVSSYLNRARWSWGDQTSVHGLLTHLLRAEYGTFSLAKTNESLNLLEMLRAQWNHCVNDLTVPVLALALLG-MLLSLRSRLRCIFVCLIVTMVSIYSVFFAWRANLNIEKPLLLGVVERFWLQADAGVCVLAGLGLSWLVCCLTGHLGKGTVWNTGAWILTAGLISHMISLNHRDCDQSSNDVVDRFSREVVLSLPQGSLVLTRGDLPGNTLRYQHYCQSLRPDLSLVDQEMMTYNWYVAKLQRHLPGVTFPGHRWDPVNAVEKK---TFSIEQFLKRNLHRPVFVCIGLTEGDPSWEGSFSRWPWGVCEQLLPVKTPFDPKKWAQKTHNLYNWSEPHDSFHPGSWERVANEEMWQARMKTAFFLFDLAENAEK--EQQGRLYEISYKLYCQIVDSQVDYPANWDKNLALAAERLLQSGGRGYGLDSLMSRSIRHFSRYLKREPSDPQSKAIRSIITHLRKEREKFRDRQKA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . : .: * *..*.*:*::. * ::************ **************:::.* ::*:*:.* *: :*:**.:*** *:. * :** *:: . .*.:**.***:.***.****:.************:*::*:. *. * :.:::.*.* **: **********::**:: **** *::* ..: *:: *: * * **::**::**:****.:***:*****:::*:***::* *********:: . .: :* :* : .:*:. : ***: . : *: :.* . .* *:. *..:**:********:*.***::*******:*::* *.****:**: :*. . * : *: :: :: : : *: *** :* *:*:*::::: *:*:.:::* *******:*** ***:.****:**********:**:.*: :***** ***.**:**:.: . **.: :**: * :: .*****: ****:*: .:* **** *::*:* : *:*::* : *: :***:* : * *.*** *************.**:*.***.* . :.:** :*.** :** * ::*.**.** *:*.**:*: . . . : *:*.:**** * :: .*** * . :.***:* :.:*: ::.", "identical_positions": 323, "similar_positions": 226, "identity": "45.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4209", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2P8-1", "uniprot_id": "VAMP5_MOUSE", "id": "Q9Z2P8-1", "name": "Vesicle-associated membrane protein 5", "aln": "MAG--KELKQCQQQADEVTEIMLNNFDKVLERHGKLAELEQRSDQLLDMSSAFSKTTKTLAQQKRWENIRCRVYLGLAVAVGLLIILIVLLVVFLP--SGGDSSKP--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95183-1", "uniprot_id": "VAMP5_HUMAN", "id": "O95183-1", "name": "Vesicle-associated membrane protein 5", "aln": "MAG--IELERCQQQANEVTEIMRNNFGKVLERGVKLAELQQRSDQLLDMSSTFNKTTQNLAQKKCWENIRYRICVGLVVVGVLLIILIVLLVVFLP--QSSDSSSAPRTQDAGIASGPGN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BG37-1", "uniprot_id": "A2BG37_DANRE", "id": "A2BG37-1", "name": "", "aln": "MQNGNSRLSEAQKDVEEVKGIMLDNLNKAEERSGKLKELETRADDLLVKGKAFSKTATKVKQKKRWENIKYKVVIAAVAAAVLLGIILAVALSFSNDDNGKDASTTTTTKAP--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . .*...*::.:**. ** :*:.*. ** ** **: *:*:** ..:*.**: .: *:* ****: :: :. ... ** *::.: : * .. *:*.. ", "identical_positions": 34, "similar_positions": 43, "identity": "28.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4212", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BPM0-1", "uniprot_id": "DAAM1_MOUSE", "id": "Q8BPM0-1", "name": "Disheveled-associated activator of morphogenesis 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPRKRGG--RGISFIFCCFRNNDHPEITYRLRNDSNFALQTMEPALPMPPVEELDVMFSELVDELDLTDKHREAMFALPAEKKWQIYCSKKKDQEENKG----ATSWP---EFYIDQLNSMAARKSLLALEKEEEEE------RSKTIESLKTALRTKPMRFVTRFIDLDGLSCILNFLKTMDYETSESRIHTSLIGCIKALMNNSQGRAHVLAHSESINVIAQSLSTENIKTKVAVLEILGAVCLVPGGHKKVLQAMLHYQKYASERTRFQTLINDLDKSTGRYRDEVSLKTAIMSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDFFEMLRNEDELEFAKRFELVHIDTKSATQMFELTRRRLTHSEAYPHFMSILHHCLQMPYKRSGNTVQYWLLLDRIIQQIVIQNDKG------------------------QDPDSTPLENFNIKNVVRMLVNENEVKQWKEQAEKMRKEHNELQQKLEKKERECDAKTQEKEEMMQTLNKMKEKLEKETTEHKQVKQQVADLTAQLHELNRRAVC---------------AAVPGGPSPGAPGG----PFPSSGLGSLLPPPPPPLLSGGALPPPPPPLPPGGPPPPPGPPPLGGVLPPPGAPVSLTLKKKNIPQPTNALKSFNWSKLPENKLDGTVWTEIDDTKVFKILDLEDLERTFSAYQRQQEFFVNN-SKQKEADAIDDTLSSKLKVKELSVIDGRRAQNCNILLSRLKLSNDEIKRAILTMDEQEDLPKDMLEQLLKFVPEKSDIDLLEEHKHELDRMAKADRFLFEMSRINHYQQRLQSLYFKKKFAERVAEVKPKVEAIRSGSEEVFRSRALKQLLEVVLAFGNYMNKGQRGNAYGFKISSLNKIADTKSSIDKNITLLHYLITIVENKYPKVLNLSEELRDIPQAAKVNMTELDKEISTLRSGLKAVETELEYQKSQ-PPQPGDKFVSVVSQFITLASFSFSDVEDLLAEAKELFTKAVKHFGEEAGKIQPDEFFGIFDQFLQAVAEAKQENENMRKRKEEEERRARLEAQLKEQRERERK-------------VRKAKESSE--------ESG-EFDDLVSALRSGEVFDKDLSKLKRNRK-RISN-----------------QVTDSSRERPITKLNF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GM04-1", "uniprot_id": "A0A8I6GM04_RAT", "id": "A0A8I6GM04-1", "name": "Disheveled-associated activator of morphogenesis 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPRKRGG--RGISFIFCCFRNNDHPEITYRLRNDSNFALQTMEPALPMPPVEELDVMFSELVDELDLTDKHREAMFALPAEKKWQIYCSKKKDQEENKG----ATSWP---EFYIDQLNSMAARKSLLALEKEEEEE------RSKTIESLKTALRTKPMRFVTRFIDLDGLSCILNFLKTMDYETSESRIHTSLIGCIKALMNNSQGRAHVLAHSESINVIAQSLSTENIKTKVAVLEILGAVCLVPGGHKKVLQAMLHYQKYASERTRFQTLINDLDKSTGRYRDEVSLKTAIMSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDFFEMLRNEDELEFAKRFELVHIDTKSATQMFELTRRRLTHSEAYPHFMSILHHCLQMPYKRSGNTVQYWLLLDRIIQQIVIQNDKG------------------------QDPDSTPLENFNIKNVVRMLVNENEVKQWKEQAEKMRKEHNELQQKLEKKERECDAKTQEKEEMMQTLNKMKEKLEKETTEHKQVKQQVADLTAQLHELNRRAVC---------------ASVPGGPSPGAPGG----PFPPSGLGSLLPPPPPPLLSGGALPPPPPPLPPGGPPPPPGPPPLGGILPPPGAPVSLTLKKKNIPQPTNALKSFNWSKLPENKLEGTVWTEIDDTKVFKILDLEDLERTFSAYQRQQEFFVNNNSKQKEADAIDDALSSKLKVKELSVIDGRRAQNCNILLSRLKLSNDEIKRAILTMDEQEDLPKDMLEQLLKFVPEKSDIDLLEEHKHELDRMAKADRFLFEMSRINHYQQRLQSLYFKKKFAERVAEVKPKVEAIRSSSEEVLRSSALKQLLEVVLAFGNYMNKGQRGNAYGFKISSLNKIADTKSSIDKNITLLHYLITIVENKYPKVLNLSEELRDIPQAAKVNMTELDKEISTLRSGLKAVETELEYQKSQ-PPQPGDKFVSVVSQFITLASFSFSDVEDLLAEAKELFTKAVKHFGEEAGKIQPDEFFGIFDQFLQAVTEAKQENENMRKRKEEEERRARLEAQLKEQRERERK-------------MRKAKESSE--------ESG-EFDDLVSALRSGEVFDKDLSKLKRNRK-RISN-----------------QVTDSSRERPITKLNF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y4D1-1", "uniprot_id": "DAAM1_HUMAN", "id": "Q9Y4D1-1", "name": "Disheveled-associated activator of morphogenesis 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPRKRGG--RGISFIFCCFRNNDHPEITYRLRNDSNFALQTMEPALPMPPVEELDVMFSELVDELDLTDKHREAMFALPAEKKWQIYCSKKKDQEENKG----ATSWP---EFYIDQLNSMAARKSLLALEKEEEEE------RSKTIESLKTALRTKPMRFVTRFIDLDGLSCILNFLKTMDYETSESRIHTSLIGCIKALMNNSQGRAHVLAHSESINVIAQSLSTENIKTKVAVLEILGAVCLVPGGHKKVLQAMLHYQKYASERTRFQTLINDLDKSTGRYRDEVSLKTAIMSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDFFEMLRNEDELEFAKRFELVHIDTKSATQMFELTRKRLTHSEAYPHFMSILHHCLQMPYKRSGNTVQYWLLLDRIIQQIVIQNDKG------------------------QDPDSTPLENFNIKNVVRMLVNENEVKQWKEQAEKMRKEHNELQQKLEKKERECDAKTQEKEEMMQTLNKMKEKLEKETTEHKQVKQQVADLTAQLHELSRRAVC---------------ASIPGGPSPGAPGG----PFPSSVPGSLLPPPPPPPLPGGMLPPPPPPLPPGGPPPPPGPPPLGAIMPPPGAPMGLALKKKSIPQPTNALKSFNWSKLPENKLEGTVWTEIDDTKVFKILDLEDLERTFSAYQRQQDFFVNSNSKQKEADAIDDTLSSKLKVKELSVIDGRRAQNCNILLSRLKLSNDEIKRAILTMDEQEDLPKDMLEQLLKFVPEKSDIDLLEEHKHELDRMAKADRFLFEMSRINHYQQRLQSLYFKKKFAERVAEVKPKVEAIRSGSEEVFRSGALKQLLEVVLAFGNYMNKGQRGNAYGFKISSLNKIADTKSSIDKNITLLHYLITIVENKYPSVLNLNEELRDIPQAAKVNMTELDKEISTLRSGLKAVETELEYQKSQ-PPQPGDKFVSVVSQFITVASFSFSDVEDLLAEAKDLFTKAVKHFGEEAGKIQPDEFFGIFDQFLQAVSEAKQENENMRKKKEEEERRARMEAQLKEQRERERK-------------MRKAKENSE--------ESG-EFDDLVSALRSGEVFDKDLSKLKRNRK-RITN-----------------QMTDSSRERPITKLNF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RHJ3-1", "uniprot_id": "Q5RHJ3_DANRE", "id": "Q5RHJ3-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPRKRGGGGHGASFFFCCFQSSDHPEITYRLRED--FALQTMEPALPIPSYDELDAMFSELVDELDLTEKHREAMFALPAEKKWQIYCSKKKEQEENKG----ATSWP---EFYIDQLNSMAARKTLLALEKEEEEE------RNKTIESLKTALRTQPMRFVTRFIDLDGLTCILNFLKSMDYETTESQIHTSLIGCIKALMNNSQGRAHVLSHTESINIIAQSLATDNIKTKVAVLEIMGAVCLVPGGHKKILEAMLHYQKFACERTRFQTLLNDLDKSTGRYRDEVSLKTAIMSFINAVLSQGAGESSLEFRVHLRYEFLMLGIQPIIDKLRSHENSTLDRHLDYFEMLRNDDELTLSRRFEAIHIDTKSATQVFELVRKKLAHTDAYPHFMSVLHHCLLMPHKRSGNTVQYWLLLDRIVQQMVLQNDKG------------------------HDPDATPLENFNVKNVVRMLVNENEVKQWKEQAEKMRKDHHELQQKMEKKERECDAKTQEKEEMMQTLNKMKEKLEREMGEHKLVKQQVAEMTTRLHELSTRQIA---------------SVPGGPPVSGPLGGPLLPPPPPPPPGGMMPPPPPPPPCGAMMPPPPPP-PPGGPPPPPGRPPFGSAPPPPGAPIGPSLKKKNIPQPSNPLKSFNWAKLSENKLEGTVWADVDDGRVFKILDLEDIEKTFSAYQRQQDFFMVNNNKQK--ETEDDTLSSK-KVKELSVIDGRRAQNCNILLSRLKLSNEEIKRAILTMDEQEDLPKDMLEQMLKFVPEKSDVDLLEEHKHELDRMAKADRFLYEMSRINHYQQRLQSLYFKKKFAERIAEIKPKVEALTKASKEVLHSRNFKQLLEVVLAFGNYMNKGQRGNAYGFKISSLNKIADTKSSIDKNITLLHYLITILEKKYSKVMLFQEELKNVPEAAKVNMTELEKEINNLRSGLKSVESELDFQKKR-PQEYGDKFVSVVSQFITVASFSFSDVEDSLCEAKELFIKTVKHFGEDADKMQPDEFFGIFDQFLQSFAEARQENENIRRRKEEEERRARMEAQLKEQREKERK-------------ARKAKENGE--------DDGGEFDDLVSALRSGEVFDKDLSKMKRNRK-RINS-----------------QTSDSGRERPITKLNF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9MSM5-1", "uniprot_id": "M9MSM5_DROME", "id": "M9MSM5-1", "name": "", "aln": "MSSMNQMSVLMDKINTTLQSCPIVCINEPDTHSANTEILQTSPESTLEKPKAAPSGGASTSVTSLNGSCIAINGGIGEGATATASAATSTAAGVTKITITSDNGNGNASTSTKAPTTGSSIDGYKNSSLVSITSLNSCSDLSQGSTATLPISSNSCSGNNVSRHPLSNNNSGSDTSSNNFQERFDFEHWKGLLSDYNCFHGLYRYWTQCSGRSSSANDNGGGSDQQQSQSNHENGLGSEAGSFYTHNILGYTFGYPFGLKEDLDGSGNCNSNCNGSSNTNGLGLRKWLSGNTSSNETPLQKHYRHQQKKKMPGFRGRRVWCGCFKDDEPPEICV---VEGAFTLQTLTPTQPMPSVDELDTKFAELVEELDLTAPNKEAMLSLPAQKKWQIYCSRKLPLDAADGPDAAAVTQPPTAEHYIERLKELVVHISLSPEDSPSHELGNRLDGHAAFVDALKTALRTSTHSFVLRFVELDGLPALLDLLLQLDIRVANSPLHTSLIGCIKALMNNSMGRAHVLAHPTAIDTIARSLAADNIRTKIAALEILGAVCLVPGGHRKVLQAMLHFQVFATERTRFQSIVNDLDRSTYAYRDNVNLKTALMSFVNAVLNYGPGQENLEFRLHLRYEFLMLGIQPVIDKLRTHENETLDRHLDFFEMVRAEDEKEFARRFKEEHVDTKSAGSMFELLRRKLSHSPAYPHMLSLLQHMLLLPY--TGHCTEHWLLIDRVVQQIVLQVEQRPNSDLIVDPDDPEKQLKLAAESPVHDPDVAPLQ-IDVAKLVRLLVKEEQLTQARKRADELERENFDVQSRLAKKEQELDLRMQEKEDLETGLARMRERLEKESAQHSQAVQRAQTAEMRAEDLQHRLISEQQERARLERLVTEGSIPDDQKVAGLTGCNGAVSPPPAPPMLKAIPPPPPPMAPSMMPPPPPP-CPGAPPPPP---SMAQTMAP--APPKVDLPKKNVPQPTNPLKSFNWSKLPDAKLQGTVWSELDESKLYNNMELESIDKLFSAYQK------NGVSATDGSYEDLRVTGKAAKQKVLSVIDGRRAQNCTILLSKLKMSDMEISKAILSMDSNEQLQLDMVEQLLKFTPSAEERALLDEHSEDIESLARADRFLYEISKIPHYEQRLKSLHYKKRFMLTINDLVPRITSVMEASREVARSRRLRKLLELVLALGNYMNRGARGNASGFRLASLNRLADTKSSAAKGTTLLHYLVQVIERKFKDLLKLEDDIPHVREASKVSLGEMDKDIQMLRTGLADVAREIEFHRSSGPAQQGDRFLPVMREFHAQASVRFAELEDKFQDMKTRFDRAVRLFGEDGSVLQPDEFFGIFDSFLAAFAEARHDNESFRRRQEEEEKRAKQEAELKKRTIERKNKTGLMTSVARNLGLKSGSSNGDPDSPAKGGDNKGEFDDLISALRTGDVFGEDMAKFKRSRKARVLNGGGSSTGHTSPPRHGSLQREESGRERERTVRRQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: :* . **:..: *** : *:***: *: *:*. :***. *:***:***** ::***::***:********:* : .* *.: * *.**::*:.:..: :* . :. ..* : :::*******.. ** **::****..:*::* :* ..::* :*************** ******:*. :*: **:**:::**:**:*.***:**********:*:*:****:* :* ******:::****:** ***:*.****:***:****. *.* ..*:**:*************:***** ***.*******:***:* :** :::**: *:***** .:*** *::*:*: ****::*:*:* * :*: :*: .::***:**::**:*:* :: :*** :**: ::: ::**:**:*:::.* :::*:::.::: ::*.:: ***:* * : ****:: * :*:*:**:* :*. . *:. : .:*. * :. : . .* * . *.. ***** . :****** **.***** .:. .* ** * **.:***:*.******:**.: **:****:::*: :::: ::**.::: *****: . . . . .. * * ************.****:**:*: **.:***:**.:*:* **:**:***.*. .: **:**..::: :*:*****:*:*:* **:***:**::**:* : :: *:: :: ..*.** :* :::***:***:*****:* **** **:::***::****** *. ******: ::*.*: .:: :.::: .: :*:**.: *::*:*. **:** * *:::::. * : **:*:.*: :* : **. *:::** : : * * ::*: ***:.. :**********.** :.:**:::**.:*:::****:**: **:**:: ..:: :......: :. *****:****:*:**.:*::*:**.** *: . * :*.*** * . ", "identical_positions": 489, "similar_positions": 367, "identity": "33.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4214", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2E2-1", "uniprot_id": "MBD1_MOUSE", "id": "Q9Z2E2-1", "name": "Methyl-CpG-binding domain protein 1", "aln": "MAESWQDCPALGPGWKRR---ESFRKSGASFGRSDIYYQSPTGEKIRSKVELTRYLGPACDLTLFDFRQGTLCHPIPKTHPLAVPSKKKKKPSKPAKTKK----------QQVGLQRSEVRIETPQGEYKAPTATALASLSVSASASSSASASASASSHAPVCCENCGIHFSWDGVKRQRLKTLCKDCRAQRIAFNREQRMFKR---VGCGDCAACLVKEDCGVCSTCRLQLPSDVASGLYCKCERRRCLRIMEKSRGCGVCRGCQTQEDCGHCCICLRSPRPGLKRQWRCLQRRCFWGKRDSSKRG--SKVASQRHSQAPP---LPPHPASQYTEPTELHISDIAPTSPAEF------IYYCVDEDEDELQPYTNQRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGGNQKRQKCRWRQC-------LQFAMKRLLPSAGSGSGEGAGLRPYQTHQTHQKRPASARQLQLSSPLKAPWAVVTAPPGPVRDSRKQQAGR--------GSVLPQPDTDFVFLQEGTSSAMQMPGTAAASTEVPVQAAQCS---------APSWVVALPQVKQETADAPEEWTAVTTFLTSSTLQSGFPSKAADPDLSPVKQEPPGPEEDGEEKKDD-VSETTPAEEIGGVGTPVITEIFSLGG---------------------------------------------TRLRDAEAWLPR--------------------LHKLLAVNEKEYFTELQLKEEVL----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UIS9-1", "uniprot_id": "MBD1_HUMAN", "id": "Q9UIS9-1", "name": "Methyl-CpG-binding domain protein 1", "aln": "MAEDWLDCPALGPGWKRR---EVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRK----------RQVGPQSGEVRKEAPRDETKADTDTAPASFP------------------APGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKR---VGCGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHCPICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQP---LPPPPPSQSPEPTEPHPRALAPSPPAEF------IYYCVDED--ELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQC-------LQFAMKRLLPSVWSESEDGAGSPP---PYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGG--------GFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQEAQCS---------GLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGG---------------------------------------------TRFRDTAVWLPR--------------------SKDLKKPGARKQ---------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q213-1", "uniprot_id": "A0A2R8Q213_DANRE", "id": "A0A2R8Q213-1", "name": "", "aln": "MTDELNELSPESEILKPEDAVPAYLNEMHPIGEDVDSDVEDDDMSCKVTVELLPDWLKPMEEEEVGVDELMSAGRINRRKTKEKPPKVKRGRGRPPKIRHGLSRSEFKKGLHADRTMKKKRVGSLMSRKRLSRKATSVPDPSLKAEVLPRTRQRVVRSSTSTPQSTKQVPDSPAGGTSAEFNSPPRLTRVSPPSIDTSRRSFVHSPSVKVGNVTQQIISTEPGKD-VSELPLQLWLCPSLEPISPTQTQEILSQQTVGSPNFPEASLNGTMTVKESLTMTVKESLPLLSECEGCGCPFSAQKHGDTLCYRCRIKREKKRSPPNILCRKVRQDQWEVEKEKHPRKQMLQRPQRYGKTENDIVPDGGDDDDEEYWRLKKRNRRMCQRCDACRRDTDCGKCDFCMDKPKFGGSNKKRQKCRLRQCKFQSKLQFRNGMKGVPTSSLSPIKKMIKSNKLLKIKKRGRPRKKKFKNDPWEEEEEDYEVSDNDEDDQELRSSEMNGSQVRKHGKWSYTFKEDEDDAAYVEDVVDANIEEDSVILDNERSVMASNEMYNTTSGLSSQGLYYNVSGMPLSSHLIGSAPICNSGAVAMGEVIGSVPMADEMSQNGFLQIEMVKVGSSPSHYREEQQNTQQMHIADPQQ-EHTPVITQIFSLAGPETESDRDPGLIELFTSLGQSVLPAHWVCVIAKGPVLQLLQCSKLSTMADTVVQIEKGFFYQVTVQNQPLLLMHSLYSRHPTCLEKVEHVVSLLLDLEALGVCQGYQNFQMCSPWEPKMCVRAALCDLLIPKDDEHCGKCSQPVEG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::. : .. . * . : :. . *.. . . : .*** . : ... : . : :. ..* :: .:*.* :: :.. : * : .. : :: .. . :. .. : * * .::: : *.. ::: .:* * : * *: : :. : * .. * * :...* . : : ::: *. .. : . : .* .* * . : . :.: : * .* .* * * .: * .:* * ::*:.* * * ** * ***:**** *******.*:****** *** :: .** : .* * . : : . : . : . . . .: * . .: * .::.: ..: :: . . . : : . : *: :... .: .. :. : . ..: : .: :: ... . .:::: ..: : *****:****.* : : *: . : : :. : ", "identical_positions": 82, "similar_positions": 195, "identity": "10.26%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4218", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TAB3-1", "uniprot_id": "PCD19_HUMAN", "id": "Q8TAB3-1", "name": "Protocadherin-19", "aln": "---MESLLLPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRVTYDMTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLIYLSPALDAQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKCKRDNKEIRTYNCSNCLTITCLLGCFIKGQNSKCLHCISVSPISEEQDKKTEEKVSLRGKRIAEYSYGHQKKSSKKKKISKNDIRLVPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRRSESTFLNVENQNTRNTSANHIYHHSFNSQGPQQPDLIINGVPLPETENYSFDSNYVNSRAHLIKSSSTFKDLEGNSLKDSGHEESDQTDSEHDVQRSLYCDTAVNDVLNTSVTSMGSQMPDHDQNEGFHCREECRILGHSDRCWMPRNPMPIRSKSPEHVRNIIALSIEATAADVEAYDDCGPTKRTFATFGKDVSDHPAEERPTLKGKR-TVDVTICSPKVNSVIREAGNGCEAISPVTSPLHLKSSLPTKPSVSYTIALAPPARDLEQYVNNVNNGPTRPSEAEPRGADSEKVMHEVSPILKEGRNKESPGVKRLKDIVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80TF3-1", "uniprot_id": "PCD19_MOUSE", "id": "Q80TF3-1", "name": "Protocadherin-19", "aln": "---MESLLLPVLLLLAVLWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPHMGTVGLSIKVTDSNDNNPVFGESTYSVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPIINLLSVNSELVEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYNLTIQARDSGVPMLQSAKSFTVRITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDMGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKADDYDEGENGRVTYDMTEGDRGFFEIDQVNGEVRTTRTFNENSKPSYELIVVAHDHGKTSLSASALVLIYLSPALDAQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKCKRDNKEIRTYNCSNCLTITCLLGCFIKGQNSKCLHCISVSPNSEEQDKKAEEKVSLRGKRIAEYSYGHQKKSSKKKKISKNDIRLVPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRRSESTFLNVENQNTRNTTASHIYHHSFNSQGPQQPDLIINGVPLPETENYSFDSNYVNSRAHLIKSSSTFKDLEGNSLKDSGHEESDQTDSEHDVQRSLYCDTAVNDVLNTSVTSMGSQMPDHDQNEGFHCREECRILGHSDRCWMPRNPMPTRSKSPEHVRNIIALSIEATAADVEAYDDCGPTKRTFATFGKDVSSHRAEERPILKGKR-TVDVTICSPKVNSAIREAGNGCEAISPVTSPLHLKSPLPTKPSISYTVALAPPAHDLEHHAN---SGASRPSEAEPRGADNEKVMHEVNPIRKDGRDKESPSVKRLKDIVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F8W3X3-1", "uniprot_id": "PCD19_DANRE", "id": "F8W3X3-1", "name": "Protocadherin-19", "aln": "MHSKDMDFVQMFVCFLLCWTGVDAVFNLKYTVEEELRAGTKIANVTADAKVAGFALGNRQP-YLRVISNSEPRWVNLSP-AGLLITKQKIDRDAVCRQTPKCFISLEVMSNSMEICVIKIEIIDVNDNAPRFPTNHIDIEISENAAPGTRFPLEGASDPDSGSNGIQTYTITPNDIFGLEIKTRGDGSKIAELVVEKTLDRETQSRYTFELTAEDGGDPPKSGTVQLNIKVIDSNDNNPVFDEPVYTVNVLENSPINTLVIDLNATDPDEGTNGEVVYSFINFVSNLTKQMFKIDPKTGVITVNGVLDHEELHIHEIDVQAKDLGPNSIPAHCKVIVNVIDINDNAPEIKLLSENSEMVEVSENAPLGYVIALVRVSDNDSGANGKVQCRLQGNVPFRLNEFESFSTLLVDGRLDREQRDMYNLTILAEDSGYPPLRSSKSFAVKVTDENDNPPYFTKPHYQAMVLENNVPGAFLLAVSARDPDLGMNGTVSYEIIKSEVRGMSVESYVTVNSN-GEIYGVRAFNHEDTRTFEFKVSAKDGGDPPLTSNATVRIVVLDVNDNTPVMTTPPLVNGTAEVSIPKNAGVGYLVTQIKADDYDEGENGRLTYSISEGDMAYFEIDQINGEVRTTKTFGENAKPSYQITVVAHDHGQTSLSASAYIVIYLSPDLNAQEQIGPVNLSLIFIIALGSIAVILFVTMIFVAVKCKRDNKEIRTYNC-----------------------------------------------RVAEYSYGNQKKSSKKKKLSKNDIRLVPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRRSESTFLNVENQNSRNAAPNHGYHHTFTGQGPQQPDLIINGMPLPETENYSIDSSYVNSRAHLIKSTSTFKDMEGNSLKDSGHEESDQTDSEHDVQRGHYADTAVNDVLNMTVPSNNSQIPDQDQSEGFHCQDECRILGHSDRCWMPRVPIPARAKSPEHGRNVIALSIEATTVDVPHYEDCGTTKRTFATFGKDG---PDEDRAEQRGRRQTAEPAVCSPKTNGAVREAGNGREAVSPITSPVHLKSPQ-SKASSTYN---TLKCRDAERIAN-------HSLLRQPEGKDSEPAMREINTLLQDGRDKESPGSKRLKDIVL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: ::: : : ** . *::****:**** **** ****: **: *****. **. :**:*** *: *::.* :***:******** :***:***:*******.********:** *:***** **: :*::**** *:****:**:.* ****** *:*** :***::************::*******:*******:*:*.:** ******: *** *.*** *********.*..*:*.* **** ** ** ***:********:***** .:*.: *:::*:***::*::**.*.**:** *::*:****************** *.*:* ***.* *:*** ***:*****.** ***********.*** **:***** *******:*:*****:**********:* ***** *.*.* * *:*:***:* :****** *:*:**:**.:* ***.***:**:*******:*:**:***:*: *:**.*.* :**::*.* *:**.:*:****:*::***** ***** *.* ******:::*********:*:***:****** **:*:*:***** :**:*********:**.::*** .:*****:*******:**.*.:*.**:: *******:******* ::***** *:***.:*.*************** **********:************** *:******:*********:**********************************************************:**::..* ***:*..************:*********:**.***********:*****:************************. *.********* :*.* .**:**:**.*****::*************** *:* *:***** **:********:.** *:***.*********** *:*. :*:* *.: ::****.*..:****** **:**:***:****. :*.* :*. : .:* *: .* :. :*.* *.* .*:*:..: ::**:****. ********", "identical_positions": 765, "similar_positions": 228, "identity": "66.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4255", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q19AV6-1", "uniprot_id": "ZSWM7_HUMAN", "id": "Q19AV6-1", "name": "Zinc finger SWIM domain-containing protein 7", "aln": "-------------------------------------------------------MAVVLPAVVEELLSEMAAAVQESARIPDEYLLSLKFLFGSSATQALDLVDRQSITLISSPSGRRVYQVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEK------------KQEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6AV25-1", "uniprot_id": "A0A8I6AV25_RAT", "id": "A0A8I6AV25-1", "name": "", "aln": "MPTRPHSSTSRGWPGTPRLSACAMTRDDVTPPRPAFGLPRAKSSQPTGREVVRRAMAVTLPEVVEELLSEIAAAVRDSARIPDELLLSLKFVFGSSAIQALDLVDRESVTLISSPSGRRVYQVLGSSGTTYTCLASCHYCSCPAFSFSVLRKSDSLLCKHLLAIYLSQLLRNCQQLSVSDKQLTDLLLMER------------TQEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWQ2-1", "uniprot_id": "ZSWM7_MOUSE", "id": "Q9CWQ2-1", "name": "Zinc finger SWIM domain-containing protein 7", "aln": "-------------------------------------------------------MAVALPEVVEELLSEMAAAVRDSARIPDELLLSLEFVFGSSAIQALDLVDRESVTLISSPSGRRVYQVLGSSGKTYTCLASCHYCSCPAFSFSVLRKSDSLLCKHLLAIYLSQLLRNCQQLHVSDKQLTDLLMEDTRRIKGAAGTWTSKTEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A4FVI0-1", "uniprot_id": "ZSWM7_DANRE", "id": "A4FVI0-1", "name": "Zinc finger SWIM domain-containing protein 7", "aln": "-------------------------------------------------------MGSSLVSVAEQLLKDLQRTYSEIKQIPDDLLIALRFVFGPCALQALDLVDQHSVTCVSSPSGRKAFQVLGGSGRLYTCFTSCHYCPCPAFSFTVLRRNESLMCKHLLAVILSQAMGLCQQEQVSDQQMTHILSRQP------------EAST", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. * *.*:**.:: : : :***: *::*.*:**..* *******:.*:* :******:.:****.*. ***::*****.****:*:***:.:*::******: *** : *** ***:*:*.:* : .:", "identical_positions": 70, "similar_positions": 44, "identity": "33.82%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-426", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54259-1", "uniprot_id": "ATN1_HUMAN", "id": "P54259-1", "name": "Atrophin-1", "aln": "MKTRQNKDSMSMRSGRKKEAPGPREELR-----------------------SRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLS--------------------QGPARPYHPPP-------------LFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPP-GAPPPHPQLYPG-GTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTK---------PPTTPVGGGNLPSAPPPANFPHVTPN--LPPPPALRPLNNASASPPG------LGAQPLPGHLPSPHAMGQGMGG-LPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYS------SSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPS--------------------LPSQAVWSQGPPPPPPYG---------------------RLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQ--------------------------------QQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSS----------HHAHPYAMSPSLGSLRPYPPGPAHLPPP----------------HSQVSYSQAGPNGPPVSSSSNSSSST-----SQGSYPCSHPSPSQGPQGAPYPFPPVP-------TVTTSSATLSTVIATVASSPAG--------YKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGS----------------PTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRG-FNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGR-----------------------------------------------------------APVECPSLGPVPHRPPFEPGSAVATVP----------PYLGPDTPALRTLSEYARPHVMSPG--------------NRNHPFYVPLGAVDPGLLG------YNVPALYSSDPAAREREREARER---------------------------------------DLRDRLKPGFEVK---------------------------------------------------PSELEPLHGVPGPGLDPFPRHGGLALQPGP---------------------------------------------------------PGLHPFPFHPSLGPLERERLALAAGPALRPDMSYAER-------LAAERQHAERVAALGN--------------------DPLARLQMLNVTPHHHQHSHIHSHLHLHQQDAIHAASASVHPLIDPLASGSHLTRIPYPAGTLPNPLLPHPLHENEVLRHQLFAAPYRDLP--ASLSAPMSAAHQLQAMHAQS---AELQRLALEQQQWLHAHHPLHSVPLPAQEDYYSHLKKESDKPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35126-1", "uniprot_id": "ATN1_MOUSE", "id": "O35126-1", "name": "Atrophin-1", "aln": "MKTRQNKDSMSMRSGRKKEAPGPREELR-----------------------SRGRASPGGVSTSSSDGKAEKSRQTAKKARIEEPSAPKASKQGRSEEISESESEETSAPKKTKTEQELPRPQSPSDLDSLDGRSINDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLS--------------------QGPARPYHPPP-------------LFPPSPPPPDSTPRQPESGFEPHPSVPPTGYHAPMEPPTSRLFQGPPPGAPPTHPQLYPGNASGGVLSGPPMGPKGGAAASSVGAPSGGKQHPPPTTPIPISSSGASGAPPAK---------PPSAPVGGGSLPSAPPPASFPHVTPN--LPPPPALRPLNNASASPPG------MGAQPIPGHLPSPHAMGQGMSG-LPPGPEKGPTLAPSPHPLPPASSSAPGPPMRYPYS------SSSSS---AAASSSSSSSSASQYPASQALPSYPHSFPPPTSMSVSNQPPKYTQPS--------------------LPSQAVWSQGPPPPPPYG---------------------RLLANNNTHPGPFPP-TGGQSTAHPAAPTHHHHQQ--------------------------------QPQQQ------------HHHGNSGPPPPGAYPHPLESSNS----------HHAHPYNMSPSLGSLRPYPPGPAHLPPP----------------HGQVSYNQAGPNGPPVSSS-NSSGSS-----SQASYSCSHPSSSQGPQGASYPFPPVP-------PVTTSSATLSTVIATVASSPAG--------YKTASPPGPPQYSKRAPSPGSYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGS----------------PTVGPGPLPPAGPSSLSSLPPPPAAPTTGPPLTATQIKQEPAEEYEPPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRG-FNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGR-----------------------------------------------------------APVECPSLGPVPHRPPFEPGSAVATVP----------PYLGPDTPALRTLSEYARPHVMSPG--------------NRNHPFYVPLGAVDPGLLG------YNVPALYSSDPAAREREREARER---------------------------------------DLRDRLKPGFEVK---------------------------------------------------PSELEPLHGVPGPGLDPFPRHGGLALQPGP---------------------------------------------------------PGLHPFPFHPSLGPLERERLALAAGPALRPDMSYAER-------LAAERQHAERVAALGN--------------------DPLARLQMLNVTPHHHQHSHIHSHLHLHQQDAIHAASASVHPLIDPLASGSHLTRIPYPAGTLPNPLLPHPLHENEVLRHQLFAAPYRDLP--ASLSAPMSAAHQLQAMHAQS---AELQRLALEQQQWLHAHHPLHSVPLPAQEDYYSHLKKESDKPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9Q1Y5-1", "uniprot_id": "A0A8M9Q1Y5_DANRE", "id": "A0A8M9Q1Y5-1", "name": "", "aln": "MKTRTHKESMPARSGRRRGGSEERRGRRPHPSPSRAERNERQTQRTAGEELSVGRFNRRSQGHDSSESEGEEHLPPPKRQKVQDSSNPSAPPISTNTPTSAPPPASSNSQSRESDNEDGQSQGSRS--SVVGSLANSSSSISSGRDIDQDNRSSSPSLSASPLASLDSESDSPDSPKQGDKNKDGGGSKCVAEERRGSGRSEDSRPEDQKDSEGGIEGDLSPLKSSASHYTSHHGMVDNTNDPSSNRKSYFPLDSKVASKLEYTSPGGPEVIHTSSRIPSKTSTQCGKPGVGGAEYSHGNSNVSHASPLPPPPALKPLEVGQNAPSGDSKADKPEKGDKSAPPSLLPQTSTIPQQPPPPNTHHYTPTSWSGGPPTNCPGNWGYVRYPGNHHTHPSQQPPVQQQLPSVYNTTSSTRHSSHPPYLSHPHPHPHKEFLPRYGTTAERERAGREFGNRDFPASNSSSNANSSSGSICGSTSGGGGPNSNVSRDFGTSIPGQSRDYASNRDGPSGPQSGREYAPGFRDRERGTGREFPLPNQQLQAQGREFVPENTGGGGCHSRDKENRWGELSSQVRESGSNNYAGNPNQAPVGAQSSALPSATLANRDPTSSPQNSTSHPSFSTANSIPPNRDYSSPMDANVQGQTPQASSNSADLPPPPHYLREYPPPGAKDPYPPPGSSSSSVPLSGVQREFPSPPGLAPNLTREYPGGPLPHHSHYPGQTGLPMQHRDREREKDSTASSLHSNRNHPPSLSPSSSGSGTGHGHPTSSTYPPPLPPPSTSSHGQPPPIASLPGNHARQGPYSSSNQTPPTPLSPLPSPSNNPIGGFTFPLTSAPSVPLPASGVSTSCPSGCRPTPYHGTLSSHTPFSSSYHGNGNHGNSNASGNAPNNSNSTSTPSLLHSPQNNKVQPHIGNAGHNNSTSTSSTSLGGDGHPDSSSGPVPPTVIKEEPVEEREELESPPPVLRSPSPEPKPVDIPIHASQSARFHRVLDRGSGNSCARSDVLFVPLDGSKLWKKRNEAIERARREVEQRARDLREKEREREREKERERDLDRHLQQKDSGTSAGLGAAGARQGSSLFFPSSSSILLDPSSSSSSSVNPSHPAVHPQHHPAHHAAHPHHIHPSHLHPSLSHSIPHSLLLPSMAGGSPVVGGPQGALGIGLGGPYLGPDTPALRTLSEYARPHAMSPLSAAARAQAHHPHLHHHPHPHMHAHAQAHPHVHPSFFLSQFQNPALAHPHHLPADAATAAAILGFLYGGGLEGGPVHPGPGPGPGGLAGAGLGGMGFPHAVAAQRERVKPGFEFKSEERVYTAGALADPAIALSHAHSHAHSHSLLLGGGAGGGPPVSEVALYGTTPPPAPPPQALAAAARNPNPVPPPLSVPPTSSILPATLPTHQAPAGAPVTPAASAPPPQPPPPPPPPPPPTASSLHHPSPHSTFPTTHPSCQPPPLPAQAPPSERYPTPVRTPPSTERARSVERERERERVIPAAERERERDRERAGTGGGAAGGGTTAGGGGGTGGGDSLSRLQMLNVTPHHHQHSHIHSHLHLHQQDTAAGG---VHPLMDPLASGSPLARLPYPGAALGPPILAHSLTDSEVLRQQLFGGPFREMPQSSSLGGSMSAAHQLQAMQQAQSAEIQFQRLALEQQWIHHHHH-----HSLTQDEYYSHLKKESDKTL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** :*:**. ****:: .. *. * * ** . . . .**:.:.*: ..*: ::::.* *.. . . * . . .:.: .: . ::: * * . :.. : .... *. *********:***: :. .. **:*.* * :*..*. .. * * * .. ... *.:: . .** ..*.. . :*:: .* *. *.. :. . * :* . ..* . . **. .*: :.....** . :. **: ..:*. ***.. * **. **: * * . . ** *: :*** : .. * . * * . ** .::* :. *.*** :::.* ..*:*.. * *:. .: *:* : .**: * **.* : :** * * ...* .* . .*.**:* *... ::. * * *: .. *** . *:* ...* ... * ::*.* * * * * * .. .* ::. * ** *. .*...: :..:*. . *..* ..:* . *:..:* . ::*. * .* ::.:.*.. . .:*.. * . :..*.. :.:. * .. .* : * :*.* .:* .. :..* * :* . : .:. .** . ::. *:..* **:**.** * *** * ***** ** **:* ********:: **** *******: ****:**** *** : :*:.***.*****: :*:************: :*.*::. . :. * * . *: *.: **.*. * ********************.*** :: **. . . ..* : :: *** .. . : * *:*:*****.* *. * :.:.... :* * *:: * . *. :* *: .. * ** .: : *: . * .. ****:: . *. *.*:***************************: .. ****:******* *:*:***..:* *:*.*.* :.****:***..*:*::* :**...**********: . ::******** * ** :*::***********.*", "identical_positions": 402, "similar_positions": 372, "identity": "23.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4265", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TCT7-1", "uniprot_id": "SPP2B_HUMAN", "id": "Q8TCT7-1", "name": "Signal peptide peptidase-like 2B", "aln": "MAAAVAAALARLLAAFLLLAAQVACEYGMVHVVSQAGGPEGKDYCILYNPQWAHLPHDLSKASFLQLRNWTASLLCSAADLPARGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIVSRERLVPPGGNKTQYDEIGIPVALLSYKDMLDIFTRFGRTVRAALYAPKEPVLDYNMVIIFIMAVGTVAIGGYWAGSRDVKKRYMKHKRDDGPEKQEDEAVDVTPVMTCVFVVMCCSMLVLLYYFYDLLVYVVIGIFCLASATGLYSCLAPCVRRLPFGKCRIPNNSLPYFHKRPQARMLLLALFCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDIFFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPCTLVTSCAVALWRRELGVFWTGSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPSEEPATSPWPAEQSPKSRTSEEMGAGAPMREPGSPAESEGRDQAQPSPVTQPGASA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3TD49-1", "uniprot_id": "SPP2B_MOUSE", "id": "Q3TD49-1", "name": "Signal peptide peptidase-like 2B", "aln": "------MAAARLAAALLLLAAQVACEFGVLRVVSQTSRTRSRDYCILYNPQWAHLPHDLSKVSLLKLRDLSTTQLCSYLDVPAEDFTNQIALVARGNCTFYEKVRLAQGSGAHGLLIVSKEKLVPPGGNKTQYEEISIPVALLSHRDLQDIFRRFGREVMVALYAPSEPVMDYNMVIIFVMAVGTVAIGGYWAGSHDVKK-YMKHKRDDGPEKQEDEAVDVTPVMICVFVVMCCFMLVLLYYFYDRLVYVIIGIFCLASSTGLYSCLAPFVRKLPFCTCRVPDNNLPYFHKRPQARMLLLALFCVTVSVVWGIFRNEDQWAWVLQDTLGIAFCLYMLKTIRLPTFKACTLLLLVLFIYDIFFVFITPFLTKSGNSIMVEVATGPSNSSTHEKLPMVLKVPRLNTSPLSLCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRIYFVACTIAYGLGLLVTFVALVLMQRGQPALLYLVPCTLLTSCTVALWRRELGAFWTGSGFAKDAPQTPWAAT--QGPVPPKAVGSSLSEQPPSEELAKSPLSTEEAGAADPAKDPDN--PVASPLSPSNG---DEAQPIPVVKPETSA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QYI0-1", "uniprot_id": "F1QYI0_DANRE", "id": "F1QYI0-1", "name": "Signal peptide peptidase-like 2B", "aln": "------MRFLSSLLLAALIVEQVLGEYGMAHFS-DWGNSKGKDYCIFFNSQWARLPQDLSKATRLQTYDLTSSVLCSPSDVPEGGFPNSIPMVMRGNCTFYEKVRLAQINGAKGLLIVSKDRLTPPSGNKSQYEEIGIPVALLSYKDMLDISKTFGEKRQVAMYAPNEPVVDYNMVLIFLMAVGTVALGGYWAGSRDIKKRYMKHKRDDGAEKQDEETVDVTPIMICVFVVMCCSMLVLLYFFYDQLVYMTIATFCLASAVSLYSCLWPFVRRIPFGKCRIPENNLPYCHKRPQVRMLILSAFCIGVSVTWGVFRNEDQWAWILQDALGIAFCLYMLKTIRLPTFKACTLLLVVLFVYDVFFVFITPLLTKSGESIMVEVAAGPSDSSTHEKLPMVLKVPRLNSSPLVLCDRPFSLLGFGDILVPGLLVAYCHRFDILMQTSQIYFLACTIGYGIGLLITFVALTLMQMGQPALLYLVPCTLLTSLAVALWRKELPLFWTGSGFVP-------------PPIIMEQINCTQTPGPSTDEPPSNPEPATSETNNQ-----------REDPTPATQ------EEVPHLTDASNT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:. ** *:*: :. : . ...:****::*.***:**:****.: *: : ::: *** *:* .*.*.*.:* ************** .**:******:::*.**.***:**:**.*******::*: ** **. .*:***.***:*****:**:*******:*******:*:** *********.***::*:*****:* ******** ******:*** ***: *. *****:..***** * **::** .**:*:*.*** *****.***:*: **: ***.**:*********:***:*************************:***:**:*******:*****.*******:***:*:*:*************:*** ***************************** :*:*::**:****.**:***:*****.*** *************:** :*****:** *******. * : . : *.::* ...* .: . . :*: : * :.:", "identical_positions": 349, "similar_positions": 120, "identity": "58.95%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4270", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8WU66-1", "uniprot_id": "TSEAR_HUMAN", "id": "Q8WU66-1", "name": "Thrombospondin-type laminin G domain and EAR repeat-containing protein", "aln": "MSALLSLCFVLPLA-APGHGTQGWEPCTDLRPLDILAEVVPSDG-ATSGIRIVQVHGARGLQLSVAAPRTMSFPASRIFSQCDLFPEEFSIVVTLRVPNLPPKRNEYLLTVVAEESDLLLLGLRLSPAQLHFLFLREDTAGAWQTRVSFRSPALVDGRWHTLVLAVSAGVFSLTTDCGLPVDIMADVPFPATLSVKGARFFVGSRRRAKGLFMGLVRQLVLLPGSDATPRLCPSRNAPLAVLSIPRVLQALTGKPEDNEVLKYPYETNIRVTLGPQPPCTEVEDAQFWFDASRKGLYLCVGNEWVSVLAAKERLDYVEEHQNLSTNSETLGIEVFRIPQVGLFVATANR--KATSAVYKWTEEKFVSYQNIPTHQAQAWRHFTIGKKIFLAVANFEPDEKGQ-EFSVIYKWSHRKLKFTPYQSIATHSARDWEAFEVDGEHFLAVANHREGD-NHNIDSVIYKWNPATRLFEANQTIATSGAYDWEFFSVGPYSFLVVANTFNGTSTKVHSHLYIRLLGSFQLFQSFPTFGAADWEVFQIGERIFLAVANSHSYDVEMQVQNDSYVINSVIYELNVTAQAFVKFQDILTCSALDWEFFSVGEDYFLVVANSFDGRTFSVNSIIYRWQGYEGFVAVHSLPTVGCRDWEAFSTTAGAYLIYSSAKEPLSRVLRLRTR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "J3S6Y1-1", "uniprot_id": "TSEAR_MOUSE", "id": "J3S6Y1-1", "name": "Thrombospondin-type laminin G domain and EAR repeat-containing protein", "aln": "MSALLMLCAVLLLLGTPSRGARPWEPCTDLRPLDILAEVVPLNG-ATSGIRMVQVEGVRGLQFSATEPRTTSFPASRIFSSCDFFPEEFSIIVTLRVPNLPPKKNEYLLSLLAEERDTLLLGLRYSPTQLHFLFLSEDLAGAWQTRVSFWSPGLMDSRWHTLILAVSQGSFSLTTDCGLPVDIMADVSFPPTLSVRGARFFIGSRKRTKGLFTGVIRQLVLLPGSDATPQLCPSRNARLAELSIPQVLKRLTGKPDDNEVLNYPYEADMKVTLGSRPPCTKAEGAQFWFDAAQKGLYLCAGSEWVSVLAAKTKLDYVEEHQSLHTNSETLGIEVFSIPGVGLFAAAANR--KARSAIYKWTDGKFVSYQNIATHQAQSWRHFTIGKKIFLAVANFGPNERGQ-EFSVIYKWSPRKLKFTLYQRIATHSARDWEAFEVDGEHFLVVANHREGD-NHNIDSMVYRWNPSSQLFEANQSIATSGAYDWEFFTVGPYSFLVVANTFNGTSTQVHSHLYIWLVGAFQLFQSFLTFGAADWEVFHIGERIFLAVANSHSYDVQMQAQNDSYVLSSVIYELNITAQTFVKFQDIPTCSALDWEFFSVGEDHFLVVANSFDGNTFSVNSIIYRWQGYEGFVAVHKLPTFGCRDWEAFNTTAGSYLIYSSAKEPLSRVLKLRTG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F9F5-1", "uniprot_id": "E7F9F5_DANRE", "id": "E7F9F5-1", "name": "", "aln": "MSELPLLACVLLSWIITCHSG-PWRPCTDLLPLDLLSRVIPMASRVQDGIRMVQSRGARGFQFSG-SPQLFSFPSSQLFINCHIFPTEFSIIVTFKIPQVAPEKSEYIFTVLEADSDELLLGLRLSHDKLHFLHKGHGSR----KRITFKAVGLDDDRWHTLVLAVTGCYTILTVDCGTPLELLLERPFPEDLDTAGSTFFIASRRRWNGLFSGLMRQLVLLPGSDATSQICPSSEPRLSALSIPQTLLHLPIKPSSTDLPLHPYEAEVRVTAGVSPPCGHSEEGQLWFNTLKKGLFLCDGMMWLTMLQEKEKLDYVEDHQDLYTYSETFDIEVFHIPSVGLFIATANRDSNLGSGIYKWMDGRFERYQNISTYDAQAWQYFTVGKKKFLVVANCKSKEAGEPEQSVIYKWSSKKLKFIRYQTLITHSARDWEAFNIQDETFLAVANHRQGERNHNIDSVIYKWNQVTQFFEVNQTIPTAGAYDWEFFAVGPYYFLVVANTFNGRSTVIDSTIYIWLGGMFQPYQSITTFGAIDWEMFQIENRVFLAVANSQMLTEEGKIL---YSINSTIYELSMTSQTFVRFQDIETNSALDWEYFTVGDDKFLVVANSYDGNSYSLNSVIYRWQGYEGFVPVNRLSTNGCRDWEFFNTTDGYYLIYSSARAALSKVLKLRTI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * *. ** . :. *.***** ***:*:.*:* . . .***:** .*.**:*:* *: ***:*::* .*.:** ****:**:::*::.*::.**::::: : * ****** * :****. .. .*::* : .* *.*****:***: **.*** *:::: : .** *.. *: **:.**:* :*** *::************.::*** :. *: ****:.* *. **...:: :***::::** * *** . * .*:**:: :***:** * *:::* * :*****:**.* * ***:.**** ** **** *:*** : *.:*** : :* ****.*::**:*::**:*** **.*** ..* *: * ******* :**** ** : **********:::.* **.*****:*: ******::*:** :::**.**:*.*:********:**** ********** ** :.* :** * * ** :**: **** ***:*:* :*:*******: : : * :.*.****.:*:*:**:**** * ******:*:**:* *******:**.::*:**:***********.*: *.* ****** *.** * *******: .**:**:*** ", "identical_positions": 360, "similar_positions": 176, "identity": "53.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4275", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VDW0-1", "uniprot_id": "DX39A_MOUSE", "id": "Q8VDW0-1", "name": "ATP-dependent RNA helicase DDX39A", "aln": "MAEQDVENELLDYDEDEEPQAPQESTPAPPKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPVNGQVSVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEDVLKKNCPHVVVGTPGRILALVRSRSLNLRNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSATLSKEIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDLLDVLEFNQVVIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAVTFVSDENDAKILNDVQDRFEVNVAELPEEIDISTYIEQSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00148-1", "uniprot_id": "DX39A_HUMAN", "id": "O00148-1", "name": "ATP-dependent RNA helicase DDX39A", "aln": "MAEQDVENDLLDYDEEEEPQAPQESTPAPPKKDIKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPVNGQVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKKNCPHVVVGTPGRILALVRNRSFSLKNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSATLSKDIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDLLDVLEFNQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNVAELPEEIDISTYIEQSR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2AWA1-1", "uniprot_id": "A2AWA1_DANRE", "id": "A2AWA1-1", "name": "RNA helicase", "aln": "MAENDVENELLDYEEDEEPQPTVDSGATTGKKEVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDILCQAKSGMGKTAVFVLATLQQIEPVDGQVSVLVMCHTRELAFQISKEYERFSKYMSSVKCAVFFGGMSIKKDEDVLKKNCPHIVVGTPGRILALSRNKTLTLKNVKHFVLDECDKMLEQLDMRRDVQDIFRLTPHEKQCMMFSATLSKEIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDLLDVLEFNQVVIFVKSVPRCVALSQLLVEQNFPAIAIHRGMTQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAVTFVSDETDAKILNDVQDRFEVNVAELPEEIDISTYIEQSR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:****:****:*:****.. :* .:. **::*************************************************:*************************:***:*************************.*** :*****:******:********:*********** *.:::.*:************************:********************:********************************************************:****** **:**:*****************:*****************************************************************:******.*********************************", "identical_positions": 387, "similar_positions": 34, "identity": "90.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-428", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZUW5-1", "uniprot_id": "A0A8I5ZUW5_RAT", "id": "A0A8I5ZUW5-1", "name": "", "aln": "MATGGGPFEEVMHDQDLPNW--SNDSVDDRLNNMEWGGQQKKANRSSEKNKKKFGVASDKRVTNDISPESSPGVGRRRTKVPHTFPHSRYMTQMSVPEQAELEKLKQRINFSDLDQRSIGSDSQGRATAANNKRQLG-ENRKPFNFLPMQINTNKSKDATASLP----KRETTTSAQCKELFASALSN-----DLLQNCQVSEEDGRGEPAMESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLTHLIEHLKEQEKSYMKFLQKILARENEEED---VRTIDSAVGSGSVAESTSLNVDVQSEASDTTEASFSLRIRPCIEDKLGNSASQEQVSDIDVTTSPKGKGDKAPQNDRELRPNRKCSRKRGFPSKARDPQQEPMEETENLKKQHDLLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSVVTETTGSLSGVSITSELNEELNDLIQRFHNQLRDSQP-------PAVPDNRRQAESLSLTREISQSRNPSVS-EHLPDEK---------VQLFSKMRVLQEKKQKMDKLLGELHTLRDQHLNNSSFVPSTSLPRSGDKRSSTVALSAPVGFAPAVNGESNSLISSVPCPAASLVSQNESENEGHLNPAEKLQKLNEVQKRLNELRELVHYYEQTSDMMTDAVNENTK--DEETE-----ESEYDSEHEHSEPVTNIRN---PQVASTWNEVNTNSNTQRGSNNREGRSINSSCEINNRSAANIRPLTTPL-LDCRYNREGEQRLRVARGED---EEEEVEEEGVSGASLSS--RRSSLVDEAPEDEEFEQKISRLMAAKEKLKQLQDLVAMVQDDDATQ-VLVPAASNLDDFYVAEEDTKQNSNNARENSNK--VDTGVNEKTREKFYEAKLQQQQRELKQLQEERKKLIEIQEKIQAVQKACPDLQLSATSISSGPTKKYLPAITSTPTVNENETSTS--------KCDIEPEDSSVVDNELWSDMRRHEMLREELRQRRKQLEALMAEHQRRQGLAETASPVAVSLRSDGSENLGTPQQSRTEKTMATWGGSTQCALDEDGDEDGYLSEGIVRTDEEEEEEQDASSNDNFPMYHP-SMNQNSYNVKETKNRWKNHRPVSADGN-YRPLAKTRQQNIS-------MQRQENLRWVSELSYIE--EKEQWQEQINQLKKQLDFSVNICQTLMQDQQTLSCLLQTLLTGPYSVLPSNVASPQVHLIMHQLNQCYTQLTWQQNNVQRLKQMLTELMRQQNQHPEKPRSKERGSSASHPSSPSLFCPFSFPTQPVNLLNLPGFTNFPSFAPGMNFSPLFPSNFGDFSQNVSTPTEQQQPLAQNPSGKTEYMAFPKPFESSSSLGAEKQRNQKQPEEETENTKTPWLYD-QEGGVEKPFFKTGFAVSVEKATNSNRKRQPDTSRRGRQFDEESLESFSSMPDPIDPTTVTKTFKT-RKASAQASLASKDKTPKSKSKKRNSTQLKSRVKTIGYESASVSSTCEPCKSRNRHSAQTEEPVQAKLFSRKNHEQLEKIIKYSRSAEISS-------------------ETGSDFSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVSRHISESDEKEGENIKSVNSGTWVASN-SELTPSESLVTTDDETFEKNFERET----HKITEQNDADNVSVMSVSSNFEPFATDDLGNTVIHLDQALARMREYERMKTETESNSNMRCTCRVIEDEDGAAATTTVSNAEETPIIENHSSPQPTSDVSAVPCPRIDTQQLDRQIKAIMKEVIPFLKEHMDEVCSSQLLTSVRRMVLTLTQQNDESKEFVKFFHKQLGSILQDSLAKFAGRKLKDCGEDLLVEISEVLFNELAFFKLMQDLDNNSIAVKQRCKRKIEAAGVIQSYAKEAKRILEGDRGSPAGEIDDEDKDKDETETVKQTQTSEVYDAKGPKNVRSDVSDQEEDEESERCPVSINLSKAESQALTNYGSGEDENEDEEMEDFEESPVDVQTSLQANTETTEENEHDNQVLQHDLEKTQESTNVPSDQEGTSKNDQDSSPVKPCYLNILENEQHLNSATHKDSLTTTTDSSKQPDPMPLPLTASETLVPRVKEVKSAQETPESSLAGSPDTESPVLVNDYEAESGNISQKSDEEDFVKVEDLPLKLTVCSEAELRKKMVEEEQKNHLAGEICEMQTEELA---GNPQILKEPETVGAQSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0L6-1", "uniprot_id": "PCM1_MOUSE", "id": "Q9R0L6-1", "name": "Pericentriolar material 1 protein", "aln": "MATGGGPFEEVMHDQDLPNW--SNDSVDDRLNNMEWGGQQKKANRSSEKNKKKFGVASDKRVTNAISPESSPGVGRRRTKIPHTFPHSRYMTQMSVPEQAELEKLKQRINFSDLDQRSIGSDSQGRATAANNKRQLS-ENRKPFNFLPMQINTNKSKDATASLP----KREMTTSAQCKELFASALSN-----DLLQNCQVSEEDGRGEPAMESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLTHLIEHLKEQEKSYMKFLQKILAR---------------------------------------------------------------------------------------------------------DPQQEPMEETENLKKQHDLLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSVVTETTGSLSGVSITSELNEELNDLIQRFHNQLRDSQP-------PAVPDNRRQAESLSLTREISQSRNPSVS-EHLPDEK---------VQLFSKMRVLQEKKQKMDKLLGELHNLRDQHLNNSSFVPSTSLQRSGDKRSSTVALSAPVGFASAVNGEANSLISSVPCPATSLVSQNESENEGHLNPAEKLQKLNEVQKRLNELRELVHYYEQTSDMMTDAVNENTK--DEETE-----ESEYDSEHENSEPVTNIRN---PQVASTWNEVNTNSNTQCGSNNRDGRPVNSNCEINNRSAANIRALNMPP-LDCRYNREGEQRLHVAHGED---EEEEVEEEGVSGASLSS--RRSSLVDEAPEDEEFEQKISRLMAAKEKLKQLQDLVAMVQDDDATQ-VVVPAASNLDDFYAAEEDIKQNSNNARENSNK--IDTGVNEKTREKFYEAKLQQQQRELKQLQEERKKLIEIQEKIQAVQKACPDLQLSATSISSGPTKKYLPAITSTPTVNENDSSTS--------KCVIDPEDSSVVDNELWSDMRRHEMLREELRQRRKQLEALMAEHQRRQGLAETSSPVAISLRSDGSENLCTPQQSRTEKTMATWGGSTQCALDEEGDEDGYLSEGIVRTDEEEEEEQDASSNDNFPIYPP-SMNQNSYNVKETKTRWKSNRPVSADGN-YRPLAKTRQQNIS-------MQRQENLRWVSELSYIE--EKEQWQEQINQLKKQLDFSVNICQTLMQDQQTLSCLLQTLLTGPYSVLPSNVASPQVHLIMHQLNQCYTQLTWQQNNVQRLKQMLTELMRQQNQHPEKPRSKERGSSASHPSSPNLFCPFSFPTQPVNLFNLPGFTNFPSFAPGMNFSPLFPSNFGDFSQNVSTPTEQQQPLAQNPSGKTEYMAFPKPFESSSSLGAEKQRNQKQPEEEAENTKTPWLYD-QEGGVEKPFFKTGFTESVEKATNSNRKNQPDTSRRRRQFDEESLESFSSMPDPIDPTTVTKTFKT-RKASAQASLASKDKTPKSKSKKRNSTQLKSRVKNIGYESASVSSTCEPCKNRNRHSAQTEEPVQAKLFSRKNHEQLEKIIKYSRSAEISS-------------------ETGSDFSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVSRHISESDEREGENVKPVNSGTWVASN-SELTPSESLVTTDDETFEKNFERET----HKVSEQNDADNVSVMSVSSNFEPFATDDLGNTVIHLDQALARMREYERMKTETESHSNMRCTCRVIEDEDGAAAAATVSNSEETPIIENHNSPQPISDVSAVPCPRIDTQQLDRQIKAIMKEVIPFLKEHMDEVCSSQLLTSVRRMVLTLTQQNDESKEFVKFFHKQLGSILQDSLAKFAGRKLKDCGEDLLVEISEVLFNELAFFKLMQDLDNNSIAVKQRCKRKIEAAGVRQSYAKEAKRILEGDHGSPAGEIDDEDKDKDETETVKQTQTSEVYDAKGPKNVRSDVSDQEEDEESERCPVSINLSKAESQALTNYGSGEDENEDEEMEDFEESPVDIQTSLQANTETTEENEHDSQILQHDLEKTPESTNVPSDQEPTSKNDQDSSPVKPCYLNILENEQQLNSATHKDSLTTT-DSSKQPEPLPLPLAASETLVPRVKEVKSAQETPESSLAGSPDTESPVLVNDYEAESGNISQKSDEEDFVKVEDLPLKLTVYSEEELRKKMIEEEQKNHLSGEICEMQTEELA---GNSQILKEPETVGAQSI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15154-1", "uniprot_id": "PCM1_HUMAN", "id": "Q15154-1", "name": "Pericentriolar material 1 protein", "aln": "MATGGGPFEDGMNDQDLPNW--SNENVDDRLNNMDWGAQQKKANRSSEKNKKKFGVESDKRVTNDISPESSPGVGRRRTKTPHTFPHSRYMSQMSVPEQAELEKLKQRINFSDLDQRSIGSDSQGRATAANNKRQLS-ENRKPFNFLPMQINTNKSKDASTNPP----NRETIGSAQCKELFASALSN-----DLLQNCQVSEEDGRGEPAMESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLTHLIDHLKEQEKSYMKFLKKILAR---------------------------------------------------------------------------------------------------------DPQQEPMEEIENLKKQHDLLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSVVAETAGSLSGVSITSELNEELNDLIQRFHNQLRDSQP-------PAVPDNRRQAESLSLTREVSQSRKPSAS-ERLPDEK---------VELFSKMRVLQEKKQKMDKLLGELHTLRDQHLNNS----SSSPQRSVDQRS-TSAPSASVGLAPVVNGESNSLTSSVPYPTASLVSQNESENEGHLNPSEKLQKLNEVRKRLNELRELVHYYEQTSDMMTDAVNENRK--DEETE-----ESEYDSEHENSEPVTNIRN---PQVASTWNEVNSHSNAQCVSNNRDGRTVNSNCEINNRSAANIRALNMPPSLDCRYNREGEQEIHVAQGEDDEEEEEEAEEEGVSGASLSS--HRSSLVDEHPEDAEFEQKINRLMAAKQKLRQLQDLVAMVQDDDAAQGVISASASNLDDFYPAEEDTKQNSNNTRGNANKTQKDTGVNEKAREKFYEAKLQQQQRELKQLQEERKKLIDIQEKIQALQTACPDLQLSAASVGNCPTKKYMPAVTSTPTVNQHETSTS--------KSVFEPEDSSIVDNELWSEMRRHEMLREELRQRRKQLEALMAEHQRRQGLAETASPVAVSLRSDGSENLCTPQQSRTEKTMATWGGSTQCALDEEGDEDGYLSEGIVRTDEEEEEEQDASSNDNFSVCPSNSVNHNSYNGKETKNRWKNNCPFSADEN-YRPLAKTRQQNIS-------MQRQENLRWVSELSYVE--EKEQWQEQINQLKKQLDFSVSICQTLMQDQQTLSCLLQTLLTGPYSVMPSNVASPQVHFIMHQLNQCYTQLTWQQNNVQRLKQMLNELMRQQNQHPEKPGGKERGSSASHPPSPSLFCPFSFPTQPVNLFNIPGFTNFSSFAPGMNFSPLFPSNFGDFSQNISTPSEQQQPLAQNSSGKTEYMAFPKPFESSSSIGAEKPRNKKLPEEEVESSRTPWLYE-QEGEVEKPFIKTGFSVSVEKSTSSNRKNQLDTNGRRRQFDEESLESFSSMPDPVDPTTVTKTFKT-RKASAQASLASKDKTPKSKSKKRNSTQLKSRVKNIRYESASMSSTCEPCKSRNRHSAQTEEPVQAKVFSRKNHEQLEKIIKCNRSTEISS-------------------ETGSDFSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVSRHISESHEK-GENVKSVNSGTWIASN-SELTPSESLATTDDETFEKNFERET----HKISEQNDADNASVLSVSSNFEPFATDDLGNTVIHLDQALARMREYERMKTEAESNSNMRCTCRIIEDGDGAGAGTTVNNLEETPVIENRSSQQPVSEVSTIPCPRIDTQQLDRQIKAIMKEVIPFLKEHMDEVCSSQLLTSVRRMVLTLTQQNDESKEFVKFFHKQLGSILQDSLAKFAGRKLKDCGEDLLVEISEVLFNELAFFKLMQDLDNNSITVKQRCKRKIEATGVIQSCAKEAKRILE-DHGSPAGEIDDEDKDKDETETVKQTQTSEVYD--GPKNVRSDISDQEEDEESEGCPVSINLSKAETQALTNYGSGEDENEDEEMEEFEEGPVDVQTSLQANTEATEENEHDEQVLQRDFKKTAESKNVPLEREATSKNDQNNCPVKPCYLNILEDEQPLNSAAHKESPPTV-DSTQQPNPLPLRLPEMEPLVPRVKEVKSAQETPESSLAGSPDTESPVLVNDYEAESGNISQKSDEEDFVKVEDLPLKLTIYSEADLRKKMVEEEQKNHLSGEICEMQTEELA---GNSETLKEPETVGAQSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GAP5-1", "uniprot_id": "A0AC58GAP5_DANRE", "id": "A0AC58GAP5-1", "name": "", "aln": "MATGGTPFEDGTDEQEMQNWTISNGSLDDRLNNMDWGVQQKKANRSSEKNRKKFSAMSESRLTNDISPESTPGAGRRRARTPHSFPHVKYSTQMSVPDQAELDRLRQVINFTDLDERSIGSDSQGRVTAANNQRQLSTEAKKPFNFLPIHLNTNKSKEPTASTSSTPGGKEHKKQSPGKELFAPVPAVVKEPFSLDGAQRLGLEDGRGELSIDSSQIVSKLVQIREYIGKATSMRDDLVEKNDVPANVERLSLLITHLKEQEKSYLRFLQKMLARENEDDDDDEGATVDSAVGSGSVAESTSLNLEPRSETSSATG---------------------------------------------------------------HGVCREQKEELENMRKQHDLLKKMLEQQEQLRALQGRQAALLAMQQSAELAIAVMDDTVVTETTGSVSGRSITSELNDELNDLIQRFHNQLHDSQAYQTVNQSQVVPDNRRQAECLSLSREVCRSRTTHNSRGQLPSSAPLTTASTSASAKLSKLQELQDKKQTMDKILQELHSLRDQTLNNSS-------CQSVSQRSARVGMSE----RPSVLGREGNGPRPVRQGSSTYTQIDDNS-----HSADKLRKLKEVHKRLNELRELVQYYEQTSDMVVDTVNENVKEEDEETEDGSLFEAMFDSEQENHEPVTNIRNPAQPQTPSNWMDMNSLTKTRSASNNRDGR-LNTECEINNRSAANLRSLNIPSVIECQHNRDRPYVGVKDEDDEEVLEDDDGARGGGGGGGRDSDGSGSSHRSSLGGDAEYAQKVHRLQTAKQKLRQLQELVAMVQSDDTDG----TTAN-------EDEGLKQQPNNTRATAPKAQRDIALCDKARERLYEEKLKQQQHELKQLHEERQRLLEIQGKIQDIQWACPDLQSSVSSSASGQMSRKIPAAASTPAPVPLQSSSSAKANTSGLKPTTEPPPVTVTDNELWTEMRRHQMLREELRQRRKQLESLMAEQQRRSTLPDSP------FRSDTHE---TQSYSRDERTVATWGGSTQCPLGDEDDD--YSSEVGAEEDDDDDERDEGEESSSTDERHACSTQKQRNYNRNNREGLKVLREVNTSPSPRRSRGRSRQQPQSERGSSSKAKRQENLRWAADLSLAEGAAPAHWQEQITHLQKQLNFSTTMCQTLLQDQQTLSYMLQALLTGPCGVVPNNVTSPQVPLIMHQLNQCYTQLAWQQNNVNRLKQTLNDLLRQQ-QSQSSSGQQQHQSVAHDPASPSMFLNYPS----VNALNIPGLPNFSPFPTGFNFAPMFPPSVGDFQQNQASSDQHHDP---NISLKTEYMSFPPPLQRSPLNNAEK-RFQSHSDNLTDANNSSWLNSSLNRSSQRPILTSDHPSQVEQNSLSSSPVPHPSTSRDRSYIPDSQESMSSLPDRADPTTVTKTFRAGRKAAAQASLASRDKTPNMKSRRKRGRGQKN-TASVDSDSVSSDSHFE----RERSNQVKYKELNQGLLDKLTQEKLDSKTKNSKPNDLSSAYAWRTPFLSNRIACTEVPDVSSDFSLFEALRETIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYSLQDIVTRHLTEKSVA-DEQASSLGPAVWATGSQSELTPSESLATSDNDASDKIVTVKSNSVLKRVPDRDSMDNESLLSTSSNLEPFASDDLGNTVIHLDKALARMREYERMKLRAECNTDN-------PEHSSAIAAATVASPQGTQGAGHLS--------TDAHCPQIDTQQLDRQIKAIMTEVIPFLKEHVGEVCSQKLLKAVRHMVLNLTQQNDESKEFVRFFHRQLEGILQDSLSKFVGRKLQDCGEDLLVEISEILFNELAFFRLMQDLDQNTSKNKLRTKRRSDHTSPKHSPHTEEMKTLEREKTFSPSYFD-EDRDQDETERQEMPHEREE-----EKEKEAQSSEASEVEEEEGLPLSISLSKAETKALCNYGSGEDENEVEEMEEFEAGPVEVQTSLQASMDNTSEHRESSALQN----ETPQETKSDQDSSESSQLNSEPSDPKVIVQPPEEGGEEEKSASGDEEEEKE-DSTSAP----------------------VQETPQSSDSASPDTDSPVMINTDEAGSGNTSQRSDEEDFVKVEDLPIQMSVLCEEELCKRISEEQQNNNLTAEILNGNTSELTGLVGNAQTLKEPETIGAQSA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** ***: .:*:: ** ** .:*******:** ************:***.. *:.*:** *****:**.****:: **:*** :* :*****:****::*:* ***:***:**********.*****:***. * :*******:::******:.::. . :* .: *****.. : .* ::. ****** :::******:*****:** **:***:******: .******: ** *********::**:*:*** . :* ** **::*******:**:*****************:*:.** *******:**:**:**:** *******:*************:***. .*********.***:**:.:**.. * :**.. :**:: **:***.***:* ***.**** **** :* .:** . * . * *. .. .* ::: .. ::.. :.::**:**:**:**********:********:.*:**** * ***** *: :***:*: ******** **..*.* ::*: :::: ****:** :*:.**********:*.*. * ::*::**: ..:: *::: . * .*.. .* ** .. * *: **: ** :**:**:***:******.**: .:*. :*. **:.**:* .: * * .: :*:**::** **:***:*****:***::*::** *** :* ****** *.:* .. .: :** :***: ::*:* * :* ::.*****::****:**************:****:***. *.::. :*** * * . ** *:*:*********.*.::.*: * ** .. *::::*.::...... . * ::: ::.: * ..:. . *. .::*** * :*******.::** * :*****.:*:***:**..:****:******* :**:***** .*:*.**:**** :************:******:**** *.:*:*** * ... ::: * * .*.**.:* :. ** :*:**:.**..*..*:**:*:**...***.** ::. ::::* * * *****:** *:: *. .*** * :. .:: .: ..:.** . : ::*::.:... .**: : *. :. * *.: :* **:**:** *********:: ***:*******:****: **:::.. *. . .: :*.* .* * *:* . . : :: ::.: .:*:*:. * .:. ::** :..****:*****:*****************************************:*****:**::*. .*: ..:....* :.. *********.*:*::: :* . :: :::.:::. ** *::*.***:****:***********:************ .:*.::: : ..* * :** . : * : . : **:**************.*********:.****.:**.:**:***.************:***:** .******:**.****:************:********:******:*: * * **: : :. :* .* : ** :: ... :* **:*:**** : .: * *: .:: *: .* **.* *:**.*****::** ********** ****:** .**::******. : *.*:.... : : :* :..: : . :*: :.: . * *. : :**: .:. . **:. * .****:** :.****:***::* ** *** **:*************::::: .* :* *:: **:*:*:*:.** : :*.**: **.: ******:**** ", "identical_positions": 1003, "similar_positions": 576, "identity": "45.04%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4287", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K4L4-1", "uniprot_id": "POF1B_MOUSE", "id": "Q8K4L4-1", "name": "Protein POF1B", "aln": "MMSSSYWSETSSSSCGTQQPTEVLQCQPQHYHYYHQPSQAQQPPEKNVVYERVRTYSGPMNKVVQALDPLGSREVLSPLKPASSYQSLVWSDHSQELYSPTLKISTCAPSTLHITQNAEQELHSPTVKVTTYPQTTIRRYIVQNPEQEPLSPFLRGSQFFPGNNVIYEKTIRKVEKLNTDQECCPQIQCHHHVIQQPQIIHSPHCQQSHSSHQIQCITEND---SNIGHELCHGGPSQIHEQVIIQDDGPEKLDPKYFGELLADLSRKNTDLYHCLLEHLERIGGSKQDFESTD----TSEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDLTSLENDKIRLEKDLAFKENQMKEYEELLASVRANNRQQQQGLQDSSAKCQSLEENNLSLRHTLSDLEYRLKELEYCKRNLEQENKNLRIQVSETCTGPTLQAKMDEIGNHYMEMVKNLRLDKDREISKLRSQLNQYQKDVSKREGS-CSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSCGGRTTITTKKYRTQYPILGLLYDDYEYIPPGSDTQTIVIEKTEDKWTCP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WVV4-2", "uniprot_id": "POF1B_HUMAN", "id": "Q8WVV4-2", "name": "Protein POF1B", "aln": "-MSSSYWSETSSSSCGTQQLPEVLQCQPQHYHCYHQSSQAQQPPEKNVVYERVRTYSGPMNKVVQALDPFNSREVLSPLKTTSSYQNLVWSDHSQELHSPTLKISTCAPSTLHITQNTEQELHSPTVKLTTYPQTTIRKYVVQNPEQEPLSQFLRGSHFFPGNNVIYEKTIRKVEKLNTDQGCHPQAQCHHHIIQQPQVIHSAHWQQPDSSQQIQAITGNNPISTHIGNELCHSGSSQICEQVIIQDDGPEKLDPRYFGELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTD----ESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGS-CSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSTGGRTTITTKKYRTQYPILGLLYDDYEYIPPGSETQTIVIEKTEDKYTCP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40E7W1-1", "uniprot_id": "A0AB40E7W1_DANRE", "id": "A0AB40E7W1-1", "name": "", "aln": "---------------------------------------------------MTLPYG-------QSVTTLRTVTVAEPSKQTVLTSPVGLSEGSTTYRTVNLSGAQYQPVQYMNSQVEGNFMYGGARYLVPVQQQPAESYVYVRQAPRVVQP-------------VYLQNVQPVSLSSVDETDVRQVNINGQTTVFSQLSSPVKSPEPSESELVETSSIHE---EVLDLKQLKNGISTEIKTEIQEP--VAKLDNRFFGELLAEVYRKNVDIQTCISEHVAKIRGRKHLLDSTIDYKMEKEEFESLIPKGVSELTKQQIRYLLQTRMTADKTMHLVMTTFSSLREELVHMQEDLRRLESEKEDLERDLNFKADQAQQYDRLLETVREQNRQLQMSLKESNNAQRTLESQLLTFQSKDPTKDFRIKELEGSKRALEQENELLRKKLAGQCSSSTIQIKTQELSREYEKMLNDLREEKDKELKSLRSQLIKIQSESTIIQTTDTSSLELRISELLSKLEQRESVIRHQEEEIRRLKLQKTDSSSSSTR----TVVTKRYMNQYPILGLLSDDYQYTAPIKEDRTMVIERTGEVKTRII", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .*. *:: .: : * .* * : . : *: * : .*. : * :* : ::. : :.. * . . *: . . :. :* :.:: *. ..*: * : : : .*: . : :. .*. :: : :: :. : :.* * : * : *** ::******:: ***.*: *: **: :* * *: ::** .*::*******:**:*******:** * :**:::**::***.:**** *:*:*: **.:* **:** ** * ::*:.** :** :*:* * .*::*. ::**.: *::: . . ::*:**** .** *****: ** ::: *:.. :* * :*:...* :*:::** :**:*: ***** : :.: : : : *.::::: ** * **:::*:*::*.**: :*: : .* ...: *:.**:* .******** ***:* .* .: :*:***:* : * ", "identical_positions": 165, "similar_positions": 182, "identity": "27.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4289", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N442-1", "uniprot_id": "GUF1_HUMAN", "id": "Q8N442-1", "name": "Translation factor GUF1, mitochondrial", "aln": "MWTLVGRGWGCARALAPRATGAALLVAPGPRSAPTLGAAPESW-------ATDRLYSSAEFKEKLDMSRFPVENIRNFSIVAHVDHGKSTLADRLLELTGTIDKTKNNKQVLDKLQVERERGITVKAQTASLFYNCEGKQYLLNLIDTPGHVDFSYEVSRSLSACQGVLLVVDANEGIQAQTVANFFLAFEAQLSVIPVINKIDLKNADPERVENQIEKVFDIPSDECIKISAKLGTNVESVLQAIIERIPPPKVHRKNPLRALVFDSTFDQYRGVIANVALFDGVVSKGDKIVSAHTQKTYEVNEVGVLNPNEQPTHKLYAGQVGYLIAGMKDVTEAQIGDTLCLHKQPVEPLPGFKSAKPMVFAGMYPLDQSEYNNLKSAIEKLTLNDSSVTVHRDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNASVILTTPTVPYKAVLSSSKLIKEHREKEITIINPAQFPDKSKVTEYLEPVVLGTIITPDEYTGKIMMLCEARRAVQKNMIFIDQNRVMLKYLFPLNEIVVDFYDSLKSLSSGYASFDYEDAGYQTAELVKMDILLNGNTVEELVTVVH--------KDKAHSIGKAICERLKDSLPRQLFEIAIQAAIGSKIIARETVKAYRKNVLAKCYGGDITRKMKLLKRQAEGKKKLRKIGNVEVPKDAFIKVLKTQSSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C3X4-1", "uniprot_id": "GUF1_MOUSE", "id": "Q8C3X4-1", "name": "Translation factor Guf1, mitochondrial", "aln": "MWALVGR------ALAPWAAGARHAAASEPR-------------------AACRLFSAAELKEKPDMSRFPVEDIRNFSIIAHVDHGKSTLADRLLELTGTIDKTKKNKQVLDKLQVERERGITVKAQTASLFYSFGGKQYLLNLIDTPGHVDFSYEVSRSLSACQGVLLVVDANEGIQAQTVANFFLAFEAQLSVIPVINKIDLKNADPERVGKQIEKVFDIPSEECIKISAKLGTNVDSVLQAVIERIPPPKVHRENPLKALVFDSTFDQYRGVIANIALFDGVVSKGDKIVSAHTKKAYEVNEVGILNPNEQPTHKLYAGQVGFLIAGMKDVTEAQIGDTLYLHNHPVEPLPGFKSAKPMVFAGVYPIDQSEYNNLKSAIEKLTLNDSSVTVHRDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNASVILTTPTVPYKAVLSSAKLIKEYKEKEITIINPAQFPEKSQVTEYLEPVVLGTVITPTEYTGKIMALCQARRAIQKNMTFIDENRVMLKYLFPLNEIVVDFYDSLKSLSSGYASFDYEDAGYQTAELVKMDILLNGNMVEELVTVVH--------REKAYTVGKSICERLKESLPRQLYEIAIQAAVGSKVIARETVKAYRKNVLAKCYGGDITRKMKLLKRQSEGKKKLRKIGNIEIPKDAFIKVLKTQPNK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32T7J6-1", "uniprot_id": "A0AB32T7J6_DANRE", "id": "A0AB32T7J6-1", "name": "", "aln": "MMSLLRP-HGLFLPFIKRLTDIKVCRVKRRSQGCTYNITVIRHRWMKSLGSVRDLSSSATEKETFDMSKFPAERIRNFSIIAHIDHGKSTLADRLLEMTGAIAKTASNKQVLDKLQVERERGITVKAQTASLFYQHHGQTYLLNLIDTPGHVDFSYEVSRSISACQGVLLIVDANQGIQAQTVANFYLAFEAQLAIIPVINKIDLKNADPERVEKQIETVFDIPKEECIRISAKLGTNVEQVLQEVVKRIPPPAVRVEDPFKGLVFDSTFDHYRGVVANIALFGGRVSRGDRIVSAHLGKSFEVNELGILRPDQHPTETLYAGQVGYVIAGMKEVKEAQIGDTLYLHKQPVEALPGFKPAKPMVFAGMYPMDQSEYTALRSALEKLTLNDSSVSIQKDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNASVIITAPTVPYKAVLASAKLIKEYGEEVITIINPAQFPDKSKVLEYLEPMVTGTIITPDDFTGKIMTLCQGRRGIQKNMVYIDDHRVMMKYVFPLNEIVVDFYDQLKSMSSGYASFDYEDAGYEAADLIKMDFLLNGQPVEELAVIVHKLWFLLIFRDKAYSSGKAICERLSNSIPRQMFEIAVQAAIGSKIIARETIKAFRKNVLAKCYGGDITRKMKLLKKQAEGKKKMRRIGNIDVPKDAFISVLKRK---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :*: .: :. . :. * *:* **. ***:**.* ******:**:*************:**:* ** .***************************. *: *********************:********:****:**********:*******::***************** :***.*****.:***:*********:.*** :::***** *: ::*::.********:****:**:***.* **:**:***** *::****:*:*.*:::**..*******::*****:*.******** **::***.*****.********:**:*****. *:**:**********::::************************************:*:*********:*:*****: *: **********:**:* *****:* **:*** ::***** **:.**.:**** :**::***:**:************.***:**************::*:*:***:****: ****..:** ::**:: **:*****.:*:***::***:***:***:*****:**:*********************:*:*****:*:***:::******.*** : ", "identical_positions": 470, "similar_positions": 131, "identity": "68.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4298", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVM5-1", "uniprot_id": "CR3L3_RAT", "id": "Q5FVM5-1", "name": "Cyclic AMP-responsive element-binding protein 3-like protein 3", "aln": "MDGDISTGKMASPACAMAPLDSMEVLDLLFDGQDGILRNVDLAES---WILTREEQKVLPNSDSDEFLNSILGPGDSDPSSPIWSPADSDSGISEDLPSDSQDTPPGSGPGSANVAARCHPSKQGEGPCPSYLPSTACPEP---PRTQVHESSVAIDLDMWSTD----TLYPEEQAGSPSRFNLTVKELLLSGGGGDLQQHPLAASQLLGPGSGHCQELVLTEDEKKLLAKEGVTLPTQLPLTKYEERVLKKIRRKIRNKQSAQESRKKKKEYIDGLENRMSACTAQNQELQRKVLHLEKQNLSLLEQLKHLQALVVQSTSKPAHAGTCIAVLLLSFVLIILPSISPFTANKVDSPGDFIPVRVFSRTLHNHAASRVAPDVTPGPEVPG-------PHKG-SSGGLSADWGNFLEIPMLDDPTEELDNTTLVLANSTEDLGRATLLDWVASEPLL--GQMGLEIPGEEIWLSWVPRWLRVRVVQDALGVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XE9-1", "uniprot_id": "CR3L3_MOUSE", "id": "Q91XE9-1", "name": "Cyclic AMP-responsive element-binding protein 3-like protein 3", "aln": "MDGDIAAGKMASPVCAMAPLDSMEVLDLLFDRQDGILRNVELAEG---WILAREEQKVLLNSDSDEFLNCILGPGDSDPSSPLWSPADSDSGISEDLPSDPQDTPPRSGTEPANTVARCHTREQGKGPCPSYLPSTPCPEP---PRTQVQESSVAIDLDMWSTD----TLYPEEPAGSPSRFNLTVKELLLSGGSGDLQQHSLAASQLLGPGSGHCQELVLTEDEKKLLAKEGVTLPTQLPLTKYEERVLKKIRRKIRNKQSAQESRKKKKEYIDGLENRMSACTAQNQELQRKVLHLEKQNLSLLEQLKHLQALVVQSTSKPAHAGTCIAVLLLSFALIILPSISPFNSNKVDSPGDFVPVRVFSRTLHNHAASRVAPDVTPGSEVPGPWPDVGTPHKGPSSGGLSADWGNFLEIPMLDNLTEELDNSTLVLANSTEDLGRATLLDWVASEPLLSPGRVGLEIPG-EMWLSWVPRWLRVRLVQDALGVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68CJ9-1", "uniprot_id": "CR3L3_HUMAN", "id": "Q68CJ9-1", "name": "Cyclic AMP-responsive element-binding protein 3-like protein 3", "aln": "MNTDLAAGKMASAACSMDPIDSFELLDLLFDRQDGILRHVELGEG---WGHVKDQQ-VLPNPDSDDFLSSILGSGDSLPSSPLWSPEGSDSGISEDLPSDPQDTPPRSGP--ATSPAGCHPAQPGKGPCLSYHPGNSCSTTTPGPVIQVPEASVTIDLEMWSPGGRICAEKPADPVDLSPRCNLTVKDLLLSGSSGDLQQHHLGASYLLRPGAGHCQELVLTEDEKKLLAKEGITLPTQLPLTKYEERVLKKIRRKIRNKQSAQESRKKKKEYIDGLETRMSACTAQNQELQRKVLHLEKQNLSLLEQLKKLQAIVVQSTSKSAQTGTCVAVLLLSFALIILPSISPFGPNKTESPGDFAPVRVFSRTLHNDAASRVAADAVPGSEAPGPRPEADTTREE-SPGSPGADWG-FQDTANLTNSTEELDNATLVLRNATEGLGQVALLDWVAPGPSTGSGRAGLEAAGDEL---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LYG4-1", "uniprot_id": "CR3LB_DANRE", "id": "Q1LYG4-1", "name": "Cyclic AMP-responsive element-binding protein 3-like protein 3-B", "aln": "MDHYSDQGG-----------DGIELLDLLFDKNDGILRYENMGQQNNQLWPVQDPHMMMTPQGNEDFFNALIGGSDSVSGSPVWSPSPSDSGISEDPHSDHIDSPPPNAS--PPMEPHIVVSQTQHSLNINFPFDFNGWETG-----FLPDQSGGTQCASETPQ-----------AQQTTGFPLTVKDLLLSGTPEPAAKVSQQS----------YQELILTEDEKRLLAKEGMTLPNQFPLTKYEERILKKIRRKIRNKQSAQESRKKKKEYIDGLESRMAACSAHNHELQRKVFQLEKCNISLMEQLRRLQALVMNGSNKPVQAGTCVLVLLLSFTLILLPNLKPFTDTKVSQHGDFSPMRVQSRSLHNLQSSRVLRNLDHPYSMTENAKILPRFPEDKTMEEIASLLGRLHRRPQFTEYDPESHNHS--FDQHDEHHHGDPITGHVATVTLNPRRGSRRSPHADDM---------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * *.:*:****** :***** ::.: .:: : :: ..::*:..::* .** ..**:*** ******** ** *:** ... . . : .. .: . . : : * : :. . .. ****:***** : : ***:******:******:***.*:********:*****************************.**:**:*:*:******::*** *:**:***::***:*::.:.*..::***: ******.**:**.:.** .*... *** *:** **:*** :*** : . . : : .: * : . : : * .* : : : * .: . **. . . . :: ", "identical_positions": 165, "similar_positions": 116, "identity": "33.67%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-431", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O00233-1", "uniprot_id": "PSMD9_HUMAN", "id": "O00233-1", "name": "26S proteasome non-ATPase regulatory subunit 9", "aln": "MSDEEARQSGGSSQAGVVTVSDVQELMRRKEEIEAQIKANYDVLESQKGIGMNEPLVDCEGYPRSDVDLYQVRTARHNIICLQNDHKAVMKQVEEALHQLHARDKEKQARDMAEAHKEAMSRKLGQSESQGPPRAFAKVNSISPGSPASIAGLQVDDEIVEFGSVNTQNFQSLHNIGSVVQHSEGKPLNVTVIRRGEKHQLRLVPTRWAGKGLLGCNIIPLQR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CR00-1", "uniprot_id": "PSMD9_MOUSE", "id": "Q9CR00-1", "name": "26S proteasome non-ATPase regulatory subunit 9", "aln": "MSGEDVPHRAESSEARAAAVSDIQDLMRRKEEIEAEIKANYDVLESQKGIGMNEPLVDCEGYPRADVDLYQVRTARHNIICLQNDHKALMKQVEEALHQLHARDKEKQARDMAEAREEAMNRRLA-SNSPVLPQAFARVNSISPGSPASIAGLQVDDEIVEFGSVNTQNFQSVQNVGTVVQHSEGKPLNVTVIRRGEKHQLRLIPTRWAGKGLLGCNIIPLQR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1R7L1-1", "uniprot_id": "F1R7L1_DANRE", "id": "F1R7L1-1", "name": "26S proteasome non-ATPase regulatory subunit 9", "aln": "MKMSEENRAVVSR----MTEEDVRQLIKRKDDIEEQIKAYYDMLESQAGVGMDGPLVDVEGFPRADVDLYKVRTARHSISCLQNDHKAIMVEIEEALHKLHATAKVTHEQDDTQMESSGQ--------TVETPPPFALVDAVTHGSPAAQAGLHVGDQIMEFGSVNTQNFRNLRDIASVVQHSEGKSLRVGVFRNGQEVHLNLTPQQWSGRGLLGCNIVPLHR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. .: : * : .*:::*::**::** :*** **:**** *:**: **** **:**:*****:******.* ********:* ::*****:*** * .: :* :: .... : * .** *:::: ****: ***:*.*:*:**********:.::::.:********.*.* *:*.*:: :*.* * :*:*:*******:**:*", "identical_positions": 111, "similar_positions": 66, "identity": "49.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4311", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97694-1", "uniprot_id": "CYH1_RAT", "id": "P97694-1", "name": "Cytohesin-1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDDDSYVPSDLTAEERQELEN---------------IRRRKQELLADIQR----LKEEIAEVANEIESLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENGLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFSIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNTGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEDWIKCIKAAISRDPFYEMLAARKKKVSSTKRH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QX11-1", "uniprot_id": "CYH1_MOUSE", "id": "Q9QX11-1", "name": "Cytohesin-1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDDDSYVPSDLTAEERQELEN---------------IRRRKQELLADIQR----LKEEIAEVANEIESLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENGLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFSIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNTGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEDWIKCIKAAISRDPFYEMLAARKKKVSSTKRH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15438-1", "uniprot_id": "CYH1_HUMAN", "id": "Q15438-1", "name": "Cytohesin-1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEDDSYVPSDLTAEERQELEN---------------IRRRKQELLADIQR----LKDEIAEVANEIENLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNNGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAISRDPFYEMLAARKKKVSSTKRH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BHC1-1", "uniprot_id": "A0A8M2BHC1_DANRE", "id": "A0A8M2BHC1-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGTVSELCASSFQAFLCPTVHPAPPAVPDDLTPEEKQELEN---------------IRRRKQELLEDIQR----LKDEITKVTNEIECLGSTQERINMQRSKQMAMGRKKFNMDPKKGIQFLIENELLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNPGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPSAERFICMNRGINDGGDLPEDLLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGG-RVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELFIPDNKDQVIKACKTEADGRVVEGNHTFYRISAPTTEEKEDWIKSIKSAISRDPFYEMLAARKKKASSLKRQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0E8N2-1", "uniprot_id": "Q0E8N2_DROME", "id": "Q0E8N2-1", "name": "", "aln": "MASLHQKRPSISNWFSSLRRQPKNKKCSPGLGGSESVGRKQPLQRSCLDLSTTRVGCDGCVSLEFFQSESPESRRSNSTFYVNTQNVSSAVFKDNRQPLLERGSGSDSSPSSVCVRCSCNSITKSGDRNETPTMATPKSDIKIALKPPPKPRSPSMAPYTSVATYNITKLAPDSPPPASPTLSTQTVNCSDVTTKVTEVQRLPCDEPNTELISKRTEYKHTTITTTTRTLIVSRPVELLLNENGEIIARRSPRKSRSNSLGRMLDVQNEIGTGGLFMEADPCSKNSLPPPPYIDDMRFIDDSSNSQSESERNSNIHKTNKYTSKNNNNDSKRESQQSNLCESCRMLLDRNYINTEQSDNLVILRRPSKQIKDELCEVVSEMEALDVPEDCKHSNKDKQMSIGRKKFNMDPKKGIEYLVENRLLRHDPQDVAHFLYKGEGLNKTAIGDYLGEKNDFNEDVLKAFVALHDFTNLILVQALRQFLWSFRLPGEAQKIDRMMETFAQRYCQLNPDIFTNTDTCYVLSFAIIMLNTSLHNPSVKDKPTVDQFISMNRGINNGGDLPRGLLESLYESIRTEPFKIPQDDGNDLMHTFFNPDKEGWLWKQGG-RYKSWKRRWFILNDNCLYYFEYTTDKEPRGIIPLENISVREIHDRSKPHCFELFATGGAD-IIKACKTDSEGKVVEGKHTVYRMSAATEEDQQEWIKRLTQSISHNPFYDILVQRKKKALSKS--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. ...: . :.::* :: *. .:.: * ::* :*:*: :*..*:* *. .:: : ::.**:::*************::*:** **:: :*:*:*******************:::*. :**:*** **:**:* **************************:******* * .:* .*********************.*****:.::**.******:*****. **..*****:.******:****** *******:**** * ** * *:********.***********************:*:**:.* .**:****: ... * :******:::*:****:**.**:**.* *::::*** :. :**::***::*. ****. * . ", "identical_positions": 246, "similar_positions": 107, "identity": "33.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4317", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68FS2-1", "uniprot_id": "CSN4_RAT", "id": "Q68FS2-1", "name": "COP9 signalosome complex subunit 4", "aln": "MAA-------AVRQDLAQLMNSSGSHKDLAGKYRQILEKAIQLSGTEQLEALKAFVEAMVNENVSLVISRQLLTDFCTHLPNLPDSTAKEVYHFTLEKVQPRVISFEEQVASIRQRLASIYEKEEDWRNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTNEQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLEALKHALHCTILASAGQQRSRMLATLFKDERCQQLAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSILDRAVIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVHFETREALPTWDKQIQSLCFQVNNLLEKISQTAPEWTAQAMEAQMAQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88544-1", "uniprot_id": "CSN4_MOUSE", "id": "O88544-1", "name": "COP9 signalosome complex subunit 4", "aln": "MAA-------AVRQDLAQLMNSSGSHKDLAGKYRQILEKAIQLSGTEQLEALKAFVEAMVNENVSLVISRQLLTDFCTHLPNLPDSTAKEVYHFTLEKIQPRVISFEEQVASIRQHLASIYEKEEDWRNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTNEQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLEALKHALHCTILASAGQQRSRMLATLFKDERCQQLAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSILDRAVIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVHFETREALPTWDKQIQSLCFQVNNLLEKISQTAPEWTAQAMEAQMAQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BT78-1", "uniprot_id": "CSN4_HUMAN", "id": "Q9BT78-1", "name": "COP9 signalosome complex subunit 4", "aln": "MAA-------AVRQDLAQLMNSSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLVISRQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLASIYEKEEDWRNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTNEQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLEALKHALHCTILASAGQQRSRMLATLFKDERCQQLAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSILDRAVIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVHFETREALPTWDKQIQSLCFQVNNLLEKISQTAPEWTAQAMEAQMAQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P0H6-1", "uniprot_id": "CSN4_DANRE", "id": "Q6P0H6-1", "name": "COP9 signalosome complex subunit 4", "aln": "MAS-------GVRQELAQLMNSSGSHKDLAGKYRQILEKALQFTDAEQLEALKAFVEAMVNENVSLVISRQLLTDFCAHLPNLPDDIAKVVCHFTLEKIQPRVISFEEQVASIRQHLATIYEKQEDWRNAAQVLVGIPLETGQKQYNVDYKLDTYLKIARLYLEDDDPVQAEAYINRASLLQNESTNEQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKSIVHETERLEALKHALHCTILASAGQQRSRMLATLFKDERCQQLAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSILDRAVIEHNLLSASKLYNNITFEELGALLEIPPAKAEKIASQMITEGRMNGFIDQIDGIVHFETREPLPTWDKQIQSLCFQVNNLLEKISQTAPEWTAQAIEAQMSQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V345-1", "uniprot_id": "CSN4_DROME", "id": "Q9V345-1", "name": "COP9 signalosome complex subunit 4", "aln": "MAANYGISTAALRSQLMGLINFTGTHKDQADKYRQLLKTVLTNTGQELIDGLRLFVEAIVNEHVSLVISRQILNDVGSELSKLPDDLSKMLSHFTLEKVNPRVISFEEQVAGIRFHLANIYERNQQWRDAATVLVGIPLETGQKQYSVECKLGTYLKIARLYLEDNDSVQAELFINRASLLQAETNSEELQVLYKVCYARVLDYRRKFIEAAQRYNELSYRKIVDQGERMTALKKALICTVLASAGQQRSRMLATLFKDERCQHLPAYGILEKMYLERIIRRSELQEFEALLQDHQKAATSDGSSILDRAVFEHNLLSASKLYNNITFEELGALLDIPAVKAEKIASQMITEGRMNGHIDQISAIVHFENRELLPQWDRQIQSLCYQVNSIIEKISVAEPDWMDNLN------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: .:*.:* *:* :*:*** *.****:*:..: :. * ::.*: ****:***:********:*.*. :.*.:***. :* : ******::***********.** :**.***::::**:** **************.*: ** ************:*.**** :******** *:..*:**: ***************************:.**.: **: ***:** **:**********************:*.**********:**** .:**** *:* ****:*:**********:***********************:**..*****************.****..*****.** ** **:******:***.::**** : *:* : ", "identical_positions": 282, "similar_positions": 83, "identity": "68.28%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4320", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TWI9-1", "uniprot_id": "TM63B_MOUSE", "id": "Q3TWI9-1", "name": "Mechanosensitive cation channel TMEM63B", "aln": "MLPFLLATLGTAALNSSNPKDYCYSARIRSTVLQGLPFGGVPTVLALDFMCFLALLFLFSILRKVAWDYGRLALVTDADRLRRQERERV-EQEYVASAMHGDSHDRYERLTSVSSSVDFDQRDNGFCSWLTAIFRIKDDEIRDKCGGDAVHYLSFQRHIIGLLVVVGVLSVGIVLPVNFSGD-------LLENNAYSFGRTTIANLKSGNNLLWLHTSFAFLYLLLTVYSMRRHTSKMRYKEDDLVKRTLFINGISKYAESEKIKKHFEEAYPNCTVLEARPCYNVARLMFLDAERKKAERGKLYFTNLQSKENVPAMINPKPCGHLCCCVVRGCEQVEAIEYYTKLEQRLKEDYRREKEKVNEKPLGMAFVTFHNETITAIILKDFNVCKCQGCTCRGEPRASSCSEALHISNWTVTYAPDPQNIYWEHLSIRGFIWWLRCLVINVVLFILLFFLTTPAIIITTMDKFNVTKPVEYLNNPIITQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKKFLAEAAIRFECVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKKIHSGAVNQVVAAPILCLFWLLFFSTMRTGFLAPTSMFTFVVLVITIVICLCHVCFGHFKYLSAHNYKIEHTETDAVSSRSNGRPPTAGAVPKSAKYIAQVLQDSEGDGDGDGAPGSSGDEPPSSSSQDEELLMPPDGLTDTDFQSCEDSLIENEIHQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T3F8-1", "uniprot_id": "TM63B_HUMAN", "id": "Q5T3F8-1", "name": "Mechanosensitive cation channel TMEM63B", "aln": "MLPFLLATLGTTALNNSNPKDYCYSARIRSTVLQGLPFGGVPTVLALDFMCFLALLFLFSILRKVAWDYGRLALVTDADRLRRQERDRV-EQEYVASAMHGDSHDRYERLTSVSSSVDFDQRDNGFCSWLTAIFRIKDDEIRDKCGGDAVHYLSFQRHIIGLLVVVGVLSVGIVLPVNFSGD-------LLENNAYSFGRTTIANLKSGNNLLWLHTSFAFLYLLLTVYSMRRHTSKMRYKEDDLVKRTLFINGISKYAESEKIKKHFEEAYPNCTVLEARPCYNVARLMFLDAERKKAERGKLYFTNLQSKENVPTMINPKPCGHLCCCVVRGCEQVEAIEYYTKLEQKLKEDYKREKEKVNEKPLGMAFVTFHNETITAIILKDFNVCKCQGCTCRGEPRPSSCSESLHISNWTVSYAPDPQNIYWEHLSIRGFIWWLRCLVINVVLFILLFFLTTPAIIITTMDKFNVTKPVEYLNNPIITQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKKFLAEAAIRFECVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKKIHSGAVNQVVAAPILCLFWLLFFSTMRTGFLAPTSMFTFVVLVITIVICLCHVCFGHFKYLSAHNYKIEHTETDTVDPRSNGRPPTAAAVPKSAKYIAQVLQDSEVDGDGDGAPGSSGDEPPSSSSQDEELLMPPDALTDTDFQSCEDSLIENEIHQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IKF9-1", "uniprot_id": "A0A0R4IKF9_DANRE", "id": "A0A0R4IKF9-1", "name": "", "aln": "---MMIATGSTN--NTNGTQDFCYSGRIRSTVLQGLPFGGVPTVLALDFMCFLVLLCVFSFLRKVAWDYGRLALVSDADSRRNKHYQRLDEQEYVASAMQTPADSRYERLTSVSSSVDFDQRDNGLCSWLTAIFRIKDDEIREKCGEDAVHYLSFQRHIIGLLVVVGVLSVGIVLPVNFSGDQLVETGNFENNNAYSFGRTTVVNLKSGNHLLWLHTIFAFFYLLLTVYSMRRHTSKMHYKEDDLVKRTLFISGIAKYAEESEIKQHFEKAYENCVVLDARICYNVAKLMSLESERKKAERSKKFYTDLMSREHIPTMINPKPCGHLCCCIIKGCEQEEAVNYYTKLEAKLKEEYRKEREKVNTKPLGMAFVTFQNEAMAALILKDFNACQCHGCHCRRQPKSSPFSSQLHTYNWTVSYAPDPQNVYWEHLSISGLNWWVRCFVINCFLFLLLFFLTTPAIIISTMDKFNVTKPVEYLNNPIVTQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKKFLDEATIRFRCVFLPDNGAFFVNYVIASAFIGNAMDLLRIPYFLMYMIRLCLARSAAERRNVKKHQAYEFQFGAAYAWMMNVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNMYYAYLPSKLDKKIHSGAVNQVVAAPILCIFWLLFFSTVRQGFGAPTSMFTFVVLIITIIICLSHIVFGHFKYLSAHNYKIDMDGVDNGRLRGSSPP-----VKSMQTYIAQVLQDPNSD--------ETGSDQGQGSSQDE------EGVTEGDFQSGEDSLIENEVHQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::** .* *....:*:***.***************************.** :**:**************:*** *.:. :*: *********: :..********************:****************:*** *********************************** : :**********:.******:****** ***:****************:*************.**:****..:**:***:** **.**:** *****:** *::*******.* ::*:* *:*::*:*************:::**** **::****** :***:*::*:**** **********:**:::*:******.*:*:** ** :*:.*. *. ** ****:*******:******* *: **:**:*** .**:************:******************:*************************************************************************** **:***.******************************* :********************:**************** *********************************:******:*********************:********:* ** ***********:***:***.*: **************: .* *... * * . .********.: * .:*.: ..***** :.:*: **** ********:**", "identical_positions": 641, "similar_positions": 117, "identity": "76.31%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4324", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08699-1", "uniprot_id": "LEG3_RAT", "id": "P08699-1", "name": "Galectin-3", "aln": "-------MADGFSLNDALAGSGNP---------NPQGWPGAWG-----------NQP-GAGGYPGASYPGAYPGQAPPGGYPGQAPP-SAYPGPTGPSAYPGPTAPGAYPGPTAPGAFPGQPGGPGAYP---SAPGAYPSAPGAYPATGPFGAP---TGPLTVPYDMPLPGGVMPR----MLITIIGTVK-PNANSITLNFKKGNDIAFHFNPRFNENNRRVIVCNTKQDNNWGREERQS--AFPFESGKPFKIQVLVEADHFKVAVNDVHLLQYNH--RMKNLREISQLG-IIGDITLTSASHAMI-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16110-1", "uniprot_id": "LEG3_MOUSE", "id": "P16110-1", "name": "Galectin-3", "aln": "-------MADSFSLNDALAGSGNP---------NPQGYPGAWG-----------NQP-GAGGYPGAAYPGAYPGQAPPGAYPGQAPP-GAYPGQAPPSAYPGPTAPGAYPGPTAPGAYPGQP-APGAFPGQPGAPGAYPQCSGGYPAAGPYGVP---AGPLTVPYDLPLPGGVMPR----MLITIMGTVK-PNANRIVLDFRRGNDVAFHFNPRFNENNRRVIVCNTKQDNNWGKEERQS--AFPFESGKPFKIQVLVEADHFKVAVNDAHLLQYNH--RMKNLREISQLG-ISGDITLTSANHAMI-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17931-1", "uniprot_id": "LEG3_HUMAN", "id": "P17931-1", "name": "Galectin-3", "aln": "-------MADNFSLHDALSGSGNP---------NPQGWPGAWG-----------NQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPP-GAYPG-----------APGAYPGAPAPGVYPGPPSGPGAYP-----SSGQPSATGAYPATGPYGAP---AGPLIVPYNLPLPGGVVPR----MLITILGTVK-PNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQS--VFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNH--RVKKLNEISKLG-ISGDIDLTSASYTMI-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HM56-1", "uniprot_id": "A0AC58HM56_DANRE", "id": "A0AC58HM56-1", "name": "Galectin", "aln": "-----------MPLVKVLGEEGTLS--------DALDAPLQQN-----------NQQAGGPVWPGQPANPVWPGQPANPTWPGQPNQ-PAWPG-------------------QPNQQWPGQPGQP-----------TAPGWPGPAPQTGPYGAPGQVPQVLTVPLDFPLQNGAYNK----MLITINGEVK-PNAKQFTVNLRRGNDIAFHINPRFSEGGKPVIVRNSMIGNNWGREERELP-SFPFVPGKPFEMKILITDTEYKVAVNKSHLLEFKH--RVFELNQITGLS-IYNDVTLSTVNVETLQ------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPU6-1", "uniprot_id": "Q9VPU6_DROME", "id": "Q9VPU6-1", "name": "Galectin", "aln": "MNVWKAKVLTEVPFGHVLIVSGRVKPHPNKISLDLTDNVNAQNESETVFLKIEANFREGQIIRSMFQPGGGWQQEEISKNWKCDGPKNPLQPGQS--FTFRVAVLQRCFEIYVNDQLYGSFEFVKFPKQIN--YVRTYGDFEKITQFHHRMLFPLVFPRTLMCPDKVAFQSDVPRRYETGTVVAMECIAKGPPTTEFSICFQCNDTGRTVLRFHVNFDRTTVSRSYQREDNSFALSDEETEGEFPFVRGKLFKIAFGLGDRAFLIAVNGQYFTYYNFPGRPFSISTLKCFTNEVGDFAVRSLEYHSDSPLLARVEKLSII", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: ..* .* : . . * * . : : : : ** : . * . * * ...: ... : :::: .* * :. : : :: .: :. :.. . * .*.:. .:.: *** ** *:: . : : :*** :: ::. * .: :. : .*. : : . ", "identical_positions": 24, "similar_positions": 73, "identity": "7.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4327", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LM46-1", "uniprot_id": "A0ABK0LM46_RAT", "id": "A0ABK0LM46-1", "name": "", "aln": "MFLESHGSLSPVQFISRCVSSVRVQANGATWSTQKGCLPTRQPLLRVCSGACSSLCREGSQAGGKNDKGSNVLKTDLGPEAADWTLPWDVPAGSPRILTQMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGGCHLAEVWRGSERPIPCDHMMYEHLQKWGPRREEVKFFLRHEDSPTESSEQGARQSQEQRTQRNVMNVPGEKHTENGVGNPRVELTLSELQDMAARQQQQIESQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKLKERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQLEDLKKGK--------LNGFQSYNGRLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRNMEVAMMDKRISELRERLYG-----------KKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSTG---GFPLPGDPVKPQSLTIASSAAHGRSKSANDGN------------------------WPTLKQNS-ASVKSTQMAGGDWKDSGMEGTLKQG--------------AISSQPLPLSALGATDKLGIEIGKGPPPIPGVGKPLPPSYGTYPSPGPLG---PGSTSSLERRKEGSLPRPAAGPPSRQKPAP--LPPAGSAPQPSSSQQIQQRISVPPSPTYPPAGPPAFPAGDGKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPPAHGTLNKSVKAVYGKPVLPSGSASPSPLPFLHGSLGTGTTQPQPPSECAEKEAEPEGPSVPGE---GSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEG-----------TPFYQPSPSQDFVGTLADVDNGNTNANGNLDESFPPRPTAPLPDELAPSSDANDNELPSPEPEELICPQTTHQTAEPTEDNNNNVATVPSTEQIPSPVAEAPSE-EDQVPPAPLSPVVHPPTASASKRTNLKKPNSERTGHG-----LRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGIVYALWDYEAQNNDELSFHEGDAITILRRKDENETEWWWAR-LGDREGYVPKNLLGLYPRIKPRQRTLA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62415-1", "uniprot_id": "ASPP1_MOUSE", "id": "Q62415-1", "name": "Apoptosis-stimulating of p53 protein 1", "aln": "-------------------------------------------------------------------------------------------------MMPMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGGCHLAEVWRGSERPIPYDHMMYEHLQKWGPRREEVKFFLRHEDSPTESSEQGARQTQEQRTQRSVVNVPGEKRTENGVGNPRVELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSVSENEKLQKLKERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQLEDLKKGK--------LNGFQSYNGRLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRNMEVAMMDKRISELRERLYG-----------KKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSTG---GFPLPGDPVKPQSLTIASSAAHGRSKSANDGN------------------------WPPLKQNS-ASVKSTQMTG-DWKDSGMEGTLKQG--------------AISSQPLPLSALGATEKLGIEIGKGPPPIPGVGKPLPPSYGTYPSSGPLG---PGSTSSLERRKEGSLPRPGAGPPSRQKPAP--LPPASNAPQPGSSQQIQQRISVPPSPTYPPAGPPAFPTGDGKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPPAHGTLNKSVKAVYGKPVLPSGSASPSPLPFLHGSLGTGTAQPQPPSDSAEKEPEQEGPSVPGE---GSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEG-----------TPFYQPSPSQDFVGTLADMDNGNTNANGNLDEPFPPRPTAPLPEELAPSSDANDNELPSPEPEELICPQTTHQTAEPTEDNNNNVAPVPSTEQIPSPVAEAPSE-EDQVPPAPLSPVIHPPAASASKRTNLKKPNSERTGHG-----LRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGTVYALWDYEAQNSDELSFHEGDAITILRRKDENETEWWWAR-LGDREGYVPKNLLGLYPRIKPRQRTLA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96KQ4-1", "uniprot_id": "ASPP1_HUMAN", "id": "Q96KQ4-1", "name": "Apoptosis-stimulating of p53 protein 1", "aln": "-------------------------------------------------------------------------------------------------MMPMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGSCHLAEVWRGNERPIPFDHMMYEHLQKWGPRREEVKFFLRHEDSPTENSEQGGRQTQEQRTQRNVINVPGEKRTENGVGNPRVELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKLKERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQLEDLKKGK--------LNGFQSYNGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRNMEVAMMDKRISELRERLYG-----------KKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSAG---SFPVLGDPIKPQSLSIASNAAHGRSKSANDGN------------------------WPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQG--------------TVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPLG---PGSTSSLERRKEGSLPRPSAGLPSRQRPTL--LPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPAD---GSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEG-----------TPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHG-----LRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWAR-LGDREGYVPKNLLGLYPRIKPRQRTLA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AT48-1", "uniprot_id": "A0A8M3AT48_DANRE", "id": "A0A8M3AT48-1", "name": "", "aln": "-------MKKFVTIVLRGLVSLSIKPGDKTWSREHARQLKREARRRR----------------------------------------------TTSKFGKMILTVYLSDGEQALTEVPITPETTCRDVVEFCKEPGETGCHLAEVWRGNERAIPFDHMMYEHLQKWGPRKQEVKFYLRHEDSPTESSDQGSQQSQEQPSRRGGS--SSDTHNENGVGNPRVELTLSELQEMATRQQQQIEAQQQMLVAKEQRLRYLKQQERRQQQAVSETEKLQRLKERVESQEAKLKKIRAMRGQVDYSKVINGNLSAEIEHISGLFQEKQAELQAAVLRVDQLSQQLEDLRRGK--------MNGLQTLGGQVTGTAALELRKLYQELQIRNKLNQEQNSKLQQQKELLNKRNMEVTLMDKRINELRDRLYKRKAE---ARQKENLPLNRVNGPPSPQPVPGNTGRVAAVGPYIQVPVPGRQEGYAVPPEPLKPQSLGVNTQVNHARSKSDGVRKPPGPWKVSDLDIIVDPIAPPPPEPRPGPGAPPPATCSAAGSDGASPNDAGWPALNKSNTSVKPPDWKESGTDTISKTAAPAGAPADKIQDSSKIGSGPPPN----KPQPPPYGAHTSNHPLSSANSGSTSSLDRRKDVPL-RPVPSLPSNPPPPPPAWPRVPPAPTGSSSQQIQQRISVPPSPTFQPN-LPFFPPGE-RPDPPLAVAVRPFIPDKGSRPQSPRKGPATMNSSSIYHMYLQQAAP-KNYP----LNMKPAVKAVYGKPLLPPSSTPPSPLP--YGSSGAFPALQGPGGDMLDFELDLDGQLIGVPEPPAPSVDHIPRPLSPTKLTPMVHSPMRYQSDAELEVLRKKLANAPRPLKKRSSITEPEGPNGPNIQKLLYQRFNTLAGGMEGGIGGVSGPGGVTPFYQPSVST--AEMIFDVDNGNPPS-----EIPAVPSEGAVAEEVVLQGDANDNEPPEEEAESISPPAP-----EPSEDSNNN--PAESIALLPSPVAEASTPEEADTSLS---------SQPTGKRTNLKKPDSERTGHG-----LRVKFNPLALLLDASLEGEFDLVQRIIYEVDNPSTANDEGITPLHNAVCAGHHHIVKFLLDFGVNVNASDSDGWTPLHCAASCNSVHLCKLLVESGAAIFATTISDVETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGMVYALWNYEAQSADELSFQEGDAITVLRRKDDSETDWWWSK-LNDKEGYVPRNLLGLYPRIKPRQRSLA-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86BG1-1", "uniprot_id": "Q86BG1_DROME", "id": "Q86BG1-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------MLTCVCRPVSGNLPKMPPASLMPAHRASASSASSSTSSTASLAFVS------------------------------------PTRGVVVTSEPKLNVPSR----------------------LTSAELRAMALRQQQQIDSQHQLLATKEQRLRFLKSQEVRSAVASAEGERLRRLRERVEAQESKLRRLRALRGQVDLQKTYNVTLSNDLDSIRALFSEKEKELSLAVAKVEALTRQLEELRRDRRCPVNILTAAGNGVGGQSLPPQASRELEKLRRELMYRNQLSLQQDARLHMQREALQQRQAELRSTDQRIYELQTRLQRKKQANTHHQQQQQQQQQHQQQQHQQQHQQTTVQQQQQQQQQLHVQSAQLLAAAAAATAQQQQQHQQHQQQQQQQQQQSASNLGKHGG-------------VAALKQQLLQKQVNQLAAAAAAAAAGRARGNVAAVEPFIHTPQ---------KSTITSTASYLSGGMKHAAATANTNQQNQLIQDLTHVKLGQNSGFFAGSVPVPVASSSCESDESKLAKKLLAAPAKTEAELRKQAQTEAMDSTTHIYAEVGPKKRDREAAAAAAAAAAAAAAAAQAAAEAANQAATAAAASAISPPATANASKIPKSTTSSSSSASALISKLNQQATAKESQDQQQSQAKKNEISVTSETLSERNTQQQLTVHSMPLGAISKSVALAVSNASKPLQVQVSNVAVP----------PRKPISSVAPNSVSSGSSIPKMITYSPKVNRVAPNVVMTDPRPALPPKPSKMSPTEQPSPVEANTSGSAGGAG-----------SGAASASTANKTQTATFGLQSLNINDNLPIKAKPLTIRKQPLFEQPRLKSSQSSSNGQQKPP---LLQLQNQRKSEPSARQPTENLPDTSPQHSPSSESSADETDRMVAPSITTSQQETSTSATSTTTTVTTSNIKERTGNGKPKLGRRVSFDPLALLLDASLEGELELVKKTAMQVANPSAANDEGITALHNAICAGHIDIVKFLVEFGCDVNAQDSDGWTPLHCAASCNNLSMVKFLVESGACLFASTLSDHETPAEKCEEDEEGFDGCSEYLYSIQEKLGILHNGDVYAVFSYEAQNGDELSFHVNEPLIVLRKGDDAENEWWWARNAAGEEGYVPRNLLGLYPRVPPHSPHFSD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: * . . : . * : .: * .. .... . . ** * **.. .. . : :: ** :**: ** ******: *:*:*.:*****::**.** *. : :* *:*::*:****:** **:::**:***** .* * .** ::: : .:*.**: *:. *: :*: *::***:*::.: * . :. *: **.:* :** **:*. :*:::*: *:* *::*: *: *:** **: ** :: :: : . * . : ::* . . . : * . : :.:* . :: .. * : . *. . .. . . * ... *: ... *. .: . * * .. . . : ::* :...:.: . . .. .: . :.* . :. .: * . * .*** : : . : : : .. . . . *. . .: . . . : : ** .: . * * . . .::* . *.::. . .*. * : .: :.* * : ..* : .::. * .: : ... ...: . . **: . .: . : **. :.* . .. : .: . * .. .****:* ** *:*************::**:: :* :** .******.****:**** .*****::** :*** ***************.: : * ******.:**:*:** **.*:**** ***: **::**.:*****::::* .**::.****. *****: .:.: :**: *: *.:***:: ..*****:********: *:. :: ", "identical_positions": 258, "similar_positions": 300, "identity": "20.27%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4336", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LV79-1", "uniprot_id": "F1LV79_RAT", "id": "F1LV79-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MAAAGPSTRASSAAGAAALSRRGRRGRCDEMAAAKAGAPGPASSPALLVLRP-------APRPEESGCTGCLETPGEVAALPCSHSRCRGCASR---AAGPGCRRCGPRGSGWARRRARDDGQAAADLMGERARRGQPERCRPRRDGGAAASGPRPEPEP---LAEPEFIFRTPIKLSKSGELGEEYGCLRKLRGEKLQEEKTCEDQVHKILQEDSEVGKRKADEQKKREEPAVLKTGLEQCPARLSDSENEEPSRGQMMQTHRSAFVSKNSSYSLAFLAGKLNTKVQRSQSCSDTIQDRVRSRLRTAPPSRAKITTITPGSTPIIGVLLSTQNSRCLSAPDLTIEKRLPFS----SLSSLASLHKPERSISPESNDSISEELNHFKPIVCSPCTPPKRLPDGRVLSPLIIKSTPRNLSRSLQKQTSYEASPRILKKWEQIFQERQIKKTLSKATLTSLAPEAGEELPGSEAIHSSKERPSLALSTRLSRVQVLSECAGPTSTALEYFPSVNQTKVEQDCVRKRSHEAPLETCHSSEHRGVASGPSLEGEQFEESRSTVDATLVKTCISTVMKTTTVNSLLPKNDVLDGVLKTKKQLRTLSHFDLGNGILVNSLGEEPTPSLRRGRKRRCKTKHLEQNG-VKKLRPPSSDMGLAPKDPGLLEVGQKLQQEEEGQQLALQSQRMFDSERRTMSRRKGSVDQYLLRSSSLAGAK----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q7F2-1", "uniprot_id": "RN169_MOUSE", "id": "E9Q7F2-1", "name": "E3 ubiquitin-protein ligase RNF169", "aln": "MAAAGPSTRASSAAAAAALSRRGRRGRCDEMAAAKAGAPGPASSPALLVLRS-------APRPEESGCTGCLETPGEVAALPCSHSRCRGCASR---AAGPGCRRCRPRGSGWARRRARDDGQAAAELMGERARRGQPEPCRPRRDGGAAASGPRPEPEP---LAEPEFIFRTPIKLSKPGELSEEYGCLRKLRGEKLQEEKDCDDQIHKLLQEDSEMGKRKADEQKKRDEAVVLKTSLEQCPARLSDSENEEPSRGQMMQTHRSAFVSKNSSCSLAFLAGKLNTKVQRSQSCSDTVQDRVRSRLRTAPPNRAKITTITPGSTPIIGVLLSTQNNRCLSAPDLTIEKRLPFG----SLSSLASLHKPERSISPESNDSISEELNHFKPIVCSPCTPPKRLPDGRVLSPLIIKSTPRNLTRSLQKQTSYEASPRILKKWEQIFQERQIKKTLSKATLTSLAPEAGEEFPGSDTIHSSKERPSLAFNTRLSRVQVLSECAGPTSTALECFPSVNQTKVEQDCVRKRSREFSLETCHSSEHGGASSGPSLEREQCEESGSTVDATLVKTCISTVMKTAAVNSLLPKNDVLGGVLKTKQQLKTLNHFDLGNGILVNSLGEEPIPSLRRGRKRRCKTKHLEQNG-VKKLRPPSSDMDLAPKDPGLLEVGRKLQQEEEDQQLALQSHRMFDSERRTMSRRKGSVDQYLLRSSSLAGAK----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCN4-1", "uniprot_id": "RN169_HUMAN", "id": "Q8NCN4-1", "name": "E3 ubiquitin-protein ligase RNF169", "aln": "MAAAGPSTRASSAAAAAALSRRGRRGRCDETAAAKTGAPGPASGPSLLVLSPPLLQPPLPPRPEESGCAGCLEPPGEAAALPCGHSLCRGCAQRAADAAGPGCPRCRARGPGWARRRARDDGQADSEVLGECARRSQPERCRPRRDGGAAAAGPRPEQEPRAAPAEPDFIFRAPIKLSKPGELREEYESLRKLREEKLQEEKPSEDQIHKLLPEDTETGKRKMDEQKKRDEPLVLKTNLERCPARLSDSENEEPSRGQMTQTHRSAFVSKNNSYSLAFLAGKLNSKVERSQSCSDTAQERAKSRVRAVPGNKAKVTTMTPASNPIIGVLLSTQNNRCVSAPDLTIEKRLPFS----SLSSLASLHKPERSVSPESNDSISEELNHFKPIVCSPCTPPKRLPDGRVLSPLIIKSTPRNLNRSLQKQTSYEASPRILKKWEQIFQERQIKKTLSKATLTSLAPEMGEELLGSEGIHSSKEKPLVAVNTRLSGGQVLSEYTGPTSADLDHFPSVSQTKAEQDSDNKSSTEIPLETCCSSELKGGGSGTSLEREQFEGLGSTPDAKLDKTCISRAMKITTVNSVLPQNSVLGGVLKTKQQLKTLNHFDLTNGVLVESLSEEPLPSLRRGRKRHCKTKHLEQNGSLKKLRQTSGEVGLAPTDPVLREMEQKLQQEEEDRQLALQLQRMFDNERRTVSRRKGSVDQYLLRSSNMAGAK----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FAP1-1", "uniprot_id": "RN169_DANRE", "id": "E7FAP1-1", "name": "E3 ubiquitin-protein ligase RNF169", "aln": "MKMAAVGSAKSTGPGQRSKSR-----------------PGALSAP---------------LSLEEARCPVCSEILLEPVTMPCGHSVCLHCFQRTVKLISLCCPLCRLRVSSWARKQSREKSLVNAELW-ELVRLSHPERCKRRMEQRDGEIPDGE-------------IFRAPVPVHKVGEMRQEYEKQKMKSGR----------------SEETDERKKKMHIK----EECVLLKHCQYPFCGVSDSENEEPVG--RRTRHVSAFVRKTRCSPAFNKSCLHSSAAQRSRSCTDSEDGRGKSRGHTNQAVPEKANIAHSYN---AGILLSSENSRSFSAPLLSLDKRHHWRGIHTSSATLVLQTKPERSISPESNDSISEELNHFKPIVCSPCTPPKRLPDGRLLEPMIVKSTPRNLTRALHKSTSYEASPTILQKWKQIEVDRQCIKVTSKGTVTSPIAEDLNLKLSPVEERDCQPCSCSVAKDRLLDLQCICGSNAHKSKSRKDKPIIYNKRR-LIFDPYNKGEEKTQVAALIKTFGDSSTPKACKELCEPS------EMGPPMLDSNAGHCNQGTVDPDHNIKINEPTTMSCVLNR-------------------PTSRRGKKRSQKTKHMEETLQTKISRTN-------RYDSLDDLIVQRMSQEKEDRELALKLQRQFDRECKKVDRHKTSRNKYELRSWGSKDGIVGYNTRRSGRVSKQNEHFNYTC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *. .: *:... : ** **. *.* **: *. * * * .::**.** * * .* . * * * ..***:::*:.. . ::: * .* .:** *: * : . ***:*: : * **: :** : . *::: *:* . : * ** . : . :******** * **** *. . . : .: .:**:**:*: : * :** :: * . . . *:***::*.*..*** *:::** : * ::*. *****:*********************************:*.*:*:*******.*:*:*.******* **:**:** :** *. **.*:** .* : .. :..: . . . ** * :. . .* . * : :.: . * :.. : * .* .. * * : . :. .:: *.:.: . .* . : . *: ***:** ****:*:. * * *. : :::.**:*.::***: :* ** * :.:.*:* * ::* *** . .. ", "identical_positions": 203, "similar_positions": 170, "identity": "27.66%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4340", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7B5-1", "uniprot_id": "D4A7B5_RAT", "id": "D4A7B5-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASSGRLGFTVRSLLNLP--------------------------------------------------------------------EQDAQPRVRCEQQTCVPQT---------------------------------------------------------------------------------------------------AAWLESE-------------------------------------------------------------------------------------------------------RSHYPSSDESGLETSPADSSQL-ASLGRASPGSD--AEKRRKRRVLFSKAQTLELERRFRQQRYLSAPEREQLARLLRLTPTQVKIWFQNHRYKLKRGRAP-GVTESSDVTASADLH----AAPGLLRRVVVPVLVHDRSPCN---------------------GRGEGTAAVPQDKCSSRLATACPVQGYTAFGPGSALGLFPAYQHLAPPALVSWNW---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70584-1", "uniprot_id": "NKX28_MOUSE", "id": "O70584-1", "name": "Homeobox protein Nkx-2.8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATSGRLGFTVRSLLNLP--------------------------------------------------------------------EQDAKPRVRREQQTCVPQT---------------------------------------------------------------------------------------------------AAWLESE-------------------------------------------------------------------------------------------------------CSHYLSSDESGLETSPADSSQL-ASLRRESPGSD--PEKRRKRRVLFSKAQTLELERRFRQQRYLSAPEREQLARLLRLTPTQVKIWFQNHRYKLKRGRAP-GITEPSDMAASSDLH----AAPGLLRRVVVPVLVHDRPPSNN--------------------GRGEGTSAVPQDKCSARLATACPVPGYTAFGPGSALGLFPAYQHLAPPALVSWNW---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15522-1", "uniprot_id": "NKX28_HUMAN", "id": "O15522-1", "name": "Homeobox protein Nkx-2.8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATSGRLSFTVRSLLDLP--------------------------------------------------------------------EQDAQHLPRREPEPRAPQPDP------------------------------------------------------------------------------------------------CAAWLDSE-------------------------------------------------------------------------------------------------------RGHYPSSDESSLETSPPDSSQR-PSARPASPGSD--AEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKRARAP-GAAESPDLAASAELH----AAPGLLRRVVVPVLVRDGQPCGGG-------------------GGGEVGTAAAQEKCGAPPAAACPLPGYPAFGPGSALGLFPAYQHLASPALVSWNW---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P8T3-1", "uniprot_id": "A0A8M9P8T3_DANRE", "id": "A0A8M9P8T3-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAISNKFSFTVRSILDLP--------------------------------------------------------------------ENDTESIVQHSPLDSFSVS-P------------------------------------------------------------------------------------------------YSTWTEND-------------------------------------------------------------------------------------------------------RGH-ISSDDSNIEASP-DSTEP-DVL---SVDTE--HEKRKKRRVLFSKAQTYELERRFRQQRYLSAPEREQLAHLLRLTPTQVKIWFQNHRYKMKRAR----------IECAQDLN----QPP-VLRRVVVPILVRDGKPYQNCT-----------------IDTEKGNGIVPP----TVPSSPFTVQGFHSLQQQTPFALFPTYQHFTNTAASRHHFCVW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22808-1", "uniprot_id": "VND_DROME", "id": "P22808-1", "name": "Homeobox protein vnd", "aln": "MTTSASLERTPSKRDRDRERDNSSGLGSAGSLPASPQSAITVSPSSPATPKRPLRTSTPSLERKREREDREDREDRKERQERHERDRDHERFAAVFSTASTTVPTNTSSSSGLAPEQLRIPTGAAAFSGFPGLHSMSSLMLPSSAAVAAAAAAPFLPWSPILLPPWNHALLPAAFYPAALRNALPGLFDAKVPSSQRSGFHISDILNLEGSELKNAAAAAAAAAHHGSDLSHHSASESTSGHRGQGSHTSPSALSPTPAGVSADEHHNGSGTGGGAGEADHHSTTEHHAPPSHPQQQHPHHQQHHHPHLLLPQQHHQQAVAPLPLAHHQSGEAQSHAHANAAAAHLLASHNAAAAAAVAAGQYLPNLPKNFPGSFGDEMSSYHHMAQTMLQHSGRSAWIKENELYGTQQPASPDSTSPVTSEVSYTYIGSNCQTSPALSGDYKSYSRSADSDALSVGDALHTLHGSSGNGSAGGAPTAHALHNNNNNTTNNNNHSLKAEGINGAGSGHDDSLNEDGIEEDIDDVDDADGSGGGDANGSDGLPNKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKTKRAQNEKGYEGHPGLLHGHATHPHHPSALPSPRRVAVPVLVRNGKPCLGDSSKLGADCVSVSSATATAMQNAAAHHLVALNGAAAYQHAAAAAAGLHAHAHAHAHAHGHGHPHAHAQRAAWWP----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * : .* : .:*:* * * . . . ::* ..: .* * ::..:* . * : : .:: :*::******:**** ******************:** *:***************** **.: : . : . ***.**:**:: * .. : :. . * : . . : * ", "identical_positions": 72, "similar_positions": 54, "identity": "9.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4343", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61353-1", "uniprot_id": "RL27_HUMAN", "id": "P61353-1", "name": "Large ribosomal subunit protein eL27", "aln": "MGKFMKPGKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSHALVAGIDRYPRKVTAAMGKKKIAKRSKIKSFVKVYNYNHLMPTRYSV-DIPLDKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKWFFQKLRF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61354-1", "uniprot_id": "RL27_RAT", "id": "P61354-1", "name": "Large ribosomal subunit protein eL27", "aln": "MGKFMKPGKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSHALVAGIDRYPRKVTAAMGKKKIAKRSKIKSFVKVYNYNHLMPTRYSV-DIPLDKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKWFFQKLRF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61358-1", "uniprot_id": "RL27_MOUSE", "id": "P61358-1", "name": "Large ribosomal subunit protein eL27", "aln": "MGKFMKPGKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSHALVAGIDRYPRKVTAAMGKKKIAKRSKIKSFVKVYNYNHLMPTRYSV-DIPLDKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKWFFQKLRF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZSW2-1", "uniprot_id": "A0A8I5ZSW2_RAT", "id": "A0A8I5ZSW2-1", "name": "60S ribosomal protein L27", "aln": "MGKFMKPGKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSHALVAGIDHYPRKVTAAMGKKKIAKRSKIKSFVKLYNYNHLVPTRYSV-DIPLDKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKWFFQKLHF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZTK5-1", "uniprot_id": "D3ZTK5_RAT", "id": "D3ZTK5-1", "name": "60S ribosomal protein L27", "aln": "MGKFMKPGKVVLVLAGRYSGYKAVIVKNIDDGTSDRPYSHVLVAGIDCYPRKVTAAMG-KKMAKRSKIKSFVKVYNYSHLMPTRYSV-DIPLDKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKWFFQKLRF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0R7P0-1", "uniprot_id": "M0R7P0_RAT", "id": "M0R7P0-1", "name": "Large ribosomal subunit protein eL27", "aln": "MGKLMKPGKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSHALVAGIDRYPRKVTAAMGKKKITKQSKIKSFVKVYNYNHFMPTRYSV-DIPLDKTVVNKDVFRDSALKRKARREVKVKFEERYKTGKNKRFFQKFRF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7ZV82-1", "uniprot_id": "RL27_DANRE", "id": "Q7ZV82-1", "name": "Large ribosomal subunit protein eL27", "aln": "MGKFMKPGKVVMVLAGRYAGRKAVIVKNIDDGTADRPYSHALVAGIDRYPRKVTATMGKKKIAKRSKIKAFVKVFNYNHLMPTRYSV-DIPLDKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKWFFQKLRF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZK92-1", "uniprot_id": "D3ZK92_RAT", "id": "D3ZK92-1", "name": "", "aln": "----------MACLS-------------------DNPYNSARVAEIGHYPREEKTTLSKKKTVKRSEIKSFVRVENYNHLRPTRCPV-DIPLDKTVVNKNIFRDPALKCKARWEAKVKFEDPLKTGRNKWFF-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VBN5-1", "uniprot_id": "Q9VBN5_DROME", "id": "Q9VBN5-1", "name": "60S ribosomal protein L27", "aln": "MRKIMKQGKIVIVLSGRYAGRKAIIVKTHDDGTPEKPFGHALVAGIDRYPRKVTKKMGKNKLKKKSKVKPFLKSLNYNHLMPTRYTAHDISFEK--LSPKDLKDPVKRKTHRFQTRVKFESVYKEGKNKWFFQKLRF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0C2H6-1", "uniprot_id": "RL27A_YEAST", "id": "P0C2H6-1", "name": "Large ribosomal subunit protein eL27A", "aln": "MAKFLKAGKVAVVVRGRYAGKKVVIVKPHDEGSKSHPFGHALVAGIERYPLKVTKKHGAKKVAKRTKIKPFIKVVNYNHLLPTRYTL-DVEAFKSVVSTETFEQPSQREEAKKVVKKAFEERHQAGKNQWFFSKLRF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0C2H7-1", "uniprot_id": "RL27B_YEAST", "id": "P0C2H7-1", "name": "Large ribosomal subunit protein eL27B", "aln": "MAKFLKAGKVAVVVRGRYAGKKVVIVKPHDEGSKSHPFGHALVAGIERYPSKVTKKHGAKKVAKRTKIKPFIKVVNYNHLLPTRYTL-DVEAFKSVVSTETFEQPSQREEAKKVVKKAFEERHQAGKNQWFFSKLRF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ..*:. . ** * ** : . . :* *::::*.*:: **.*: *** . *: * :. . :.:. : : .: **. : *:*: ** ", "identical_positions": 24, "similar_positions": 36, "identity": "17.52%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-030131-4356", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UPU5-1", "uniprot_id": "UBP24_HUMAN", "id": "Q9UPU5-1", "name": "Ubiquitin carboxyl-terminal hydrolase 24", "aln": "-MESEEEQHMTTLLCMGFSDPATIRKALRLAKNDINEAVALLTNERPGLDYGGYEPMDSGGGPSPGPGGGPRGDGGGDGGGGGPSRGGSTGGGGGFDPPPAYHEVVDAEK-NDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLLASTYLARLGLSESDENCRRFMDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLIELVAERIKQDPIPTGLLGVLTMAFNPDNEYHFKNRMKVSQRNWAEVFGEGNMFAVSPVSTFQKEPHGWVVDLVNKFGELGGFAAIQAKLHSEDIELGAVSALIQPLGVCAEYLNSSVVQPMLDPVILTTIQDVRSVEEKDLKDKRLVSIPELLSAVKLLCMRFQPDLVTIVDDLRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTLSKSVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWKIQSGQSSTVIENIHTIIAAAAVKFNSDQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARFETTSGKVLDVLWELAHLPTLPSSLIQQALEEHLTILSDAYAVKEAIKRSYIIKCIEDIKRPGEWSGLE----------------KNKKDGFKSSQLNNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLIACHRLAAAVAGPGGLSGSTLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFNLFKTFFENVNLCDHRLKRQGAQLYVEKLELIGMDFIWKIAMESPDEEIANEAIQLIINYSYINLNPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDFYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTVEAHSNETIGSVRWKIAKQLCSPVDNIQIFTNDSLLTVNKDQKLLHQLGFSDEQILTVKTSGSGTPSGSSADSSTSSSSSSSGVFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDS-----LGRKKTLLSESS-SQSSKSPSLSSKQQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDDMARSCAKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTMPTLLDEDLTKDGIEALSSRPFRNVSRQTSRQMSLCGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEVSDFTSTVACFMRLSWAAAAGRLDLVGSSQPIKES-NSLCPAGIRNRLSSSGSNCSSGSEGEPVALHAGICVRQQSVSTKDSLIAGEALSLLVTCLQLRSQQLASFYNLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSAHPDVQKPNQFLLGVILTAQLPLWSPTSIMRGVNQRLLSQCMEYFDLRCQLLDDLTTSEMEQLRISPATMLEDEITWLDNFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEMLGSSLIKPLLDDFLFRASRIILNSHSPAGSAAISQQDFHPKCSTANSRLAAYEVLVMLADSSPSNLQIIIKELLSMHHQPDPALTKEFDYLPPVDSRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGRDQIFKNTFQGIYSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGENGRSVDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEYRPKVYDQTNPYTDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNNDRLSILTKLVKKGEKKGLFVEKMPARIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKLKHPYYPCMAKVSLQLAIQFLFQTYLRTKKKLRVDTEEWIATIEALLSKSFDACQWLVEYFISSEGRELIKIFLLECNVREVRVAVATILEKTLDSALFYQDKLKSLHQLLEVLLALLDKDVPENCKNCAQYFFLFNTFVQKQGIRAGDLLLRHSALRHMISFLLGASRQNNQIRRWSSAQAREFGNLHNTVALLVLHSDVSSQRNVAPGIFKQRPPISIAPSSPLLPLHEEVEALLFMSEGKPYLLEVMFALRELTGSLLALIEMVVYCCFCNEHFSFTMLHFIKNQLETAPPHELKNTFQLLHEILVIEDPIQVERVKFVFETENGLLALMHHSNHVDSSRCYQCVKFLVTLAQKCPAAKEYFKENSHHWSWAVQWLQKKMSEHYWTPQSNVSNETSTGKTFQRTISAQDTLAYATALLNEKEQSGSSNGSESSPANENGDRHLQQGSESPMMIGELRSDLDDVDP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B1AY13-1", "uniprot_id": "UBP24_MOUSE", "id": "B1AY13-1", "name": "Ubiquitin carboxyl-terminal hydrolase 24", "aln": "-MESEEEQHMTTLLCMGFSDPATIRKALRLAKNDINEAVALLTNERPGLDYGGYEPMDSGG-PSPGPGGGPRGDSGSDGS--GPSRGGSTGGGGGFDPPPAYHEVVDAEK-NDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLLASTYLARLGLSESDENCKRFMERCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLIELVAERMKQDPIPIGLLGVLTMAFNPDNEYHFKNRMKVSQRNWAEVFGEGNMFAISPVSTFQKEPHGWVVDLVNKFGELGGFAAIQAKLHSEDIELGAVSALVQPLGVCAEYLNSSVVQPMLDPVILTTIQDVRSVEEKDLKDKRLVSIPELLSAIKLLCMRFQPALVTTVDALRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTLSKSVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWKIQSGQSSTVIENIHTIIAAAAVKFNADQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARFEATSGKVLDVLWELAHLPTLPSSLIQQALEEHLTILSDAYAVKEAVKRSYIIKCIEDIKRPGEWSSLE----------------KNKKDGFKSSQLNNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLLACHRLAAAVAGPGGLTGLTLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFNLFKTFFENVNLCDHRLKRQGAQLYVEKLELVGMDFIWKIAMESPDEEIANEAIQLIINYSYINLNPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDFYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTVEAHSNETIGSVRWKIAKQLCSPVDNIQIFTNDSLLTVNKDQKLLHQLGFSDEQVLTVKTSGSGTPSGSSADSSTSSSSSSSGAFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDS-----LGRKKTLLSETS-SQSSKSPSLSSKQQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDDMARSCAKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTMPTSLDEDLTKDGIEALSSRPFRNVSRQTSRQMSLCGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEASDFTATVACFMRLSWAAAAGRLDLVGSSQPIKES-NSLFPAGIRSRLSSSGSNCSSSSEGEPAALHAGICVRQQSVSTKDALIAGEALSLLVTCLQLRSQQLASFYSLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSAHPEVQKPNQFLLGVILTAQLPLWSPTSIMRGVNQRLLSQCMEYFDLRCQLLDDLTTSEMDQLRISPATMLEDEITWLDNFEPNRTADCETSEADNILLAGHLRLIKTLLSLCGAEKEMLGSSLIKPLLDDFLFRASRIIVNSHSPASSAAISQQDFHPKCSTVNSRLAAYEVLVMLADSSPSNLQIITKELLSMHHQPDPALTKEFDYLPPVDSRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGREQIFKNTFQGIYSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVAGMARQDSSSEVGENGRNMDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEYRPKVYDQTNPYTDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNNDRLSILTKLVKKGEKKGLFVEKMPARIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKLKHPYYPCMAKVSLQLAIQFLFQTYLRTKKKLRVDTEEWIATIEALLSKSLDACQWLVEYFISSEGRELVKVFLLECSVREVRVAVATILEKTLDSALFYQDKLKSLHQLLEVLLALLDKDVPENCKNCAQYFSLFNTFVQKQGIRAGDLLLRHSALRHMISFLLGVSRQNSQIRRWSSAQAREFGNLHNTVALLVLHSDVSSQRNVAPGIFKQRPPISVAPSSPLLPLHEEVEALLFLSEGKPYLLEVMFALRELTGSLLALMEMVVYCCFCNEHFSFTMLHFIKNQLETAPPHELKNTFQLLHEVLVIEDPIQVERVKFVFETENGLLALMHHSNHVDSSRCYQCVKFLVTLAQKCPAAKEYFKENSHHWSWAVQWLQKKMSEHYWTPQSNVSNETSTGKTFQRTISAQDTLAYATALLNEKEQSGSSNGSESSPANENGERHLQQGSESPMMIGELRSDLDDVDP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1Q6K1-1", "uniprot_id": "F1Q6K1_DANRE", "id": "F1Q6K1-1", "name": "Ubiquitin carboxyl-terminal hydrolase 24", "aln": "MMETEEEQHMTTLLCMGFPDPVAIRKALRLAKNDINEAVALLTNESPGLGYG-YEPMESGP--SPGSGD-------------GENSGRTVTG--GFDPPPAYHDVVESERSNDENGNCSGNSMEFPTTNLYELESRVFTDHWSIPYKREESLGKCLIASTCLARHGLADADENCKRFIDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLVDLVAERVKQDPIPIGLMGVLTMAFNPDNEYHFKNRMKACQRNWAEVFGEDSMFAVSPSSSYQKEPHGWLVDLVNRFGEMGGFTAIQCKLNQEEIEIGCVSALVQPLGVCAEYLNSSLVQPMLDPVIHKMITYVQNLEEKDLKDKRLVSIPELLSAIKLLCMRFQRELVNVVDDLRLDILLRMLKTPHFSAKMNSLKEVTKLIEESTVSKTVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELSKIWKIQAGQSSTVIENIHTIIAAAAVKFNFDQLSHLFVLIQKSWEVESDRVRQKLLSLIGRIGREARSEATTGKVLEVLWELAHLPTLPTSLVQQALEEHLTILSDAYAVKETIKRNYIIKCIEDIKKMQIQEDSKSPSETQVSFLTGTWGKKKPSSLAKSSQQTNPQTVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLITGSLVSCHRLAVSVAGSNGLSGSTLVDGRYSYQEYLEGHLKFLAFFLQEASLYLVWNRAKEIWECLVSGMDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLEPYEITMNGFNLFKTFFENVNLSDHRLKRQGTQLCVERLDLAGMDFIWRIAMESPDEDIANEAIQLIITYSYINLNPKMKKDSVSLHKKFIADCYKRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPSRSSKLVIIERLLLLAERYVITIEDLYSVPRTILPHGASFHGHPVTLHITYESTKDTFTLEAHSNETIGSIRWKIADQLSCPVDNVQIFANDSMLTMNRDQKLLNQLGFSDEQSLTVKSSGTGTPSGSSADSSASASSSSSGVFNSAYALEQEKSLPGVVMALVCNVFEMLYQLANLEEPRITLRVRKLLLLIPTDPEVQDALDNFVPKESSVWSHQKTLFTLGSGSQASKSPSLSSKQQHQQSAASILESLFRSSAPGMSTFRVLYNLEVLSSKLMPTSDDEMAKTSVKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQAMPSILDEELSKD--DTLSSRPFRNAGRQSGRQLSVCGTPEKSSYRQVSVSDRSSIRVEEIIPAARVAIQTMEVGDFTSTVACFMRLTWAAAAGRLDLVGSSQPIRETTNSLLPLGVRSRVSSTGSNCSSSSEGEVTTLQAGICVKQLFVSIKDTIIAREALSLLVTCLQLRSQQLCSFYSLLSVNDFIIDILLGSPSGEIRRVACDQLYTLSQSDTSAYPDLQKPNLFLLKVVLTAQLPLWSPTSIMRGVNQRLLSQCTEYFDLRCQLLDDLTTSEMEQLQIGPAAMLEDEISWLDNFEPTWTTELETSEADNILLAGHLRLIKTLLSLCGTEKEQFGPSLIQQLLDDFLFRASRIILNSDS-SSSTTASIHDFHPKCSTVSSRLAAYEVLVMLADSSLTNLQLITKELLSMHHQSDPSLSKEFDYLPPVDSRSISGFVGLKNGGATCYMNAVFQQLYMQPGLPEGVLSIEDDTENPEESVFCQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLVDQLDEHLKKIGREQIFKNTFQGIFSDQKICKDCPHRYEREETFMALNLGVTSCQSLEISLDQFVRGEVLDGSNAYYCEKCKEKRTTVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWVLNMEPYTVSGMARQDSSADHGENGRGGEAGSGGSPRKKVTISENYELVGVVVHSGQAHAGHYYSFIKDRRGSARGRWYKFNDNVVEEFDMNDETLEYECFGGEYRPKVYDQSNPYPDVRRRYWNAYMLFYQRISDQNSPVLPKKSRVSIMRQEAEDLSLSAPSSPEISPQSSPRPPRANNDRLTLLTRLVKKGEKKGLFVEKMPARIFQMVRDENLKFMKNRDVYNSDYFSFTLSLASVNATKLKHASYQAMAKTSLQLAVQFLLHTYLRTKKKLRVDTEEWIATVEVLLSKSSEACQWMVQYLVAPEGREIIKICLLECSVREVRVVVATILEKTLESALYFQD--AGLDCLLDMLLSLLDKDVPDNCKNCSQYFSLFSNFAQR-GCGPCQLLLKHSAYRRMLVFLLGPNRQNNQHRRWSSAQAREFLHLHNTLALMVLHTDLTSQRTEAQGVFKQASSGLVAPSSVLMPLHPDINTLLFKADGQAYLMEVMFAMRELSGPLSFLIEMITYSSFCNEPFSLGVLQLLKNHLETAPPHELKNVFQMLLEILMLEDPLQSQRLKFAFESEKGLLALMHQSNNVDSSRCYQCVKFLVTLAQKCSPAKDYFKELSGHWSWAVQWLQKKMSEHYWTPQSNVSNETSTAKTFQRTISAQDTLAYATALLNEKDQSGSSNGSDGSPANENSDRSLRQGSESPMMLGDSRSDLEDVDP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:**************.**.:********************** ***.** ****:** ***.*. * . * :. * *********:**::*: *********:.:**************:******************:*** *** **:::****:**::**********************************::*****:****** **:********************..**********..***:** *::*******:*****:***:***:***.**:.*:**:*.****:*************:********* . * *:.:*******************:******** **. ** ***********:******************:**:**:*****************************************************:******:********************** ***.***********.********************* *:*:****:************:**:*******************::**.**********: .. : *: .. **** .*** ******************************************:****::*****.:***..**:* *******:*:****.************:*** ************:* **************************************.********************.********:** **:*:* ******:********:**********.********::****************.**************************************** **:*********************:***************** :**::**********:**********:*****.**..****:***:***:**:*:*****:******** ****:**:***********:*:******.*.*:**:******************:**************************** :*:***:: . .::***:: * **:************* **:********* ***********************:**:**::..****************************************************:**: ***:*:** ::********..**:.**:*:***********:*************************..***:********:*****************:*: *** * *:*.*:**:******.**** .:*:*****:* ** **::** *****************.***.* .* ************.***************:****:*::**** *** *:************************* ******************:**:*.**:******:*******. *:: *************************:*** :*.***: *************:**.* :.*:: * :********..**************** :***:* *********.**:*:************* ******:***********************.:**::***:**::*** ************************************************:**:**:***:**:**********:*****************:***************************:************** *****************************************:********:********:: *****. : *.********:::********:********************..:*:******.*:****:*********************:***.****************:***************::************************* *.*****::**:*******************:*****************.******.*****:*******. * .***.*****:***::*******************:*.***** :****:*:*:::.****::*: ****.******.*********:***::** .*. **::**:*******:*****:*** **..*.*: * . :***:*** *:*: **** .***.* *********** :****:**:***:*::***. * *:*** .. :**** *:*** ::::*** ::*:.**:*****:***:*.* *:**:.*..**** **: :*:::**:***********.**:* *:*::***:* :*:**.**:*:*******:**:********************..**:**** * ******************************.***********************:********:.******.:* *:********:*: ****:****", "identical_positions": 2130, "similar_positions": 360, "identity": "80.53%" } ]